Queries 4001 to 5000

GO:0004252

sp|P04432|KVD39_HUMAN
Immunoglobulin kappa variable 1D-39
Search

0.97	Immunoglobulin kappa variable 1-9

0.78	GO:0002250	adaptive immune response
0.73	GO:0002377	immunoglobulin production
0.71	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.70	GO:0038095	Fc-epsilon receptor signaling pathway
0.68	GO:0030449	regulation of complement activation
0.66	GO:0002449	lymphocyte mediated immunity
0.66	GO:0006956	complement activation
0.65	GO:0050900	leukocyte migration
0.58	GO:0006898	receptor-mediated endocytosis
0.50	GO:0006508	proteolysis

0.81	GO:0003823	antigen binding
0.56	GO:0004252	serine-type endopeptidase activity
0.39	GO:0042802	identical protein binding

0.70	GO:0005615	extracellular space
0.60	GO:1903561	extracellular vesicle
0.53	GO:0005886	plasma membrane

0.56

GO:0004252

sp|P04433|KV311_HUMAN
Immunoglobulin kappa variable 3-11
Search

0.90	Ig kappa chain V-III region VG

0.82	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response
0.53	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.52	GO:0038095	Fc-epsilon receptor signaling pathway
0.51	GO:0030449	regulation of complement activation
0.50	GO:0002449	lymphocyte mediated immunity
0.50	GO:0072376	protein activation cascade
0.49	GO:0050900	leukocyte migration
0.45	GO:0006898	receptor-mediated endocytosis
0.44	GO:0003094	glomerular filtration

0.60	GO:0003823	antigen binding
0.44	GO:0004252	serine-type endopeptidase activity
0.36	GO:0051082	unfolded protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005615	extracellular space
0.47	GO:1903561	extracellular vesicle
0.46	GO:0071745	IgA immunoglobulin complex
0.45	GO:0071753	IgM immunoglobulin complex
0.44	GO:0005886	plasma membrane

0.44

GO:0004252

sp|P04435|TVB2_HUMAN
T-cell receptor beta chain V region CTL-L17
Search

0.97	T-cell receptor beta variable 2

0.86	GO:0031295	T cell costimulation
0.85	GO:0050852	T cell receptor signaling pathway
0.74	GO:0006955	immune response

0.86	GO:0042605	peptide antigen binding
0.85	GO:0042287	MHC protein binding

0.56

GO:0005886

plasma membrane

sp|P04436|TVA1_HUMAN
T-cell receptor alpha chain V region HPB-MLT (Fragment)
Search

0.97	T-cell receptor alpha variable 19

0.83	GO:0002377	immunoglobulin production
0.72	GO:0006955	immune response
0.46	GO:0031295	T cell costimulation
0.45	GO:0050852	T cell receptor signaling pathway

0.46	GO:0042605	peptide antigen binding
0.46	GO:0042287	MHC protein binding

0.71	GO:0005615	extracellular space
0.38	GO:0005887	integral component of plasma membrane

sp|P04437|TVA2_HUMAN
T-cell receptor alpha chain V region CTL-L17
Search

0.96	T-cell receptor alpha variable 5

0.69	GO:0002377	immunoglobulin production
0.67	GO:0006955	immune response
0.62	GO:0031295	T cell costimulation
0.61	GO:0050852	T cell receptor signaling pathway

0.62	GO:0042605	peptide antigen binding
0.61	GO:0042287	MHC protein binding

0.60	GO:0005615	extracellular space
0.44	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P04440|DPB1_HUMAN
HLA class II histocompatibility antigen, DP beta 1 chain
Search

HLA-DPB1

0.67	MHC class II lymphocyte antigen beta chain

0.81	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.72	GO:0006955	immune response
0.35	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.35	GO:0032729	positive regulation of interferon-gamma production
0.34	GO:0042102	positive regulation of T cell proliferation
0.33	GO:0007165	signal transduction

0.35	GO:0032395	MHC class II receptor activity
0.35	GO:0042605	peptide antigen binding

0.74	GO:0042613	MHC class II protein complex
0.34	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

sp|P04553|HSP1_HUMAN
Sperm protamine P1
Search

PRM1

0.96	Protamine 1

0.80	GO:0007283	spermatogenesis
0.76	GO:0030261	chromosome condensation
0.72	GO:0030154	cell differentiation
0.69	GO:0007275	multicellular organism development
0.40	GO:0022412	cellular process involved in reproduction in multicellular organism
0.40	GO:0006997	nucleus organization
0.40	GO:0003006	developmental process involved in reproduction
0.34	GO:0006325	chromatin organization

0.55

GO:0003677

DNA binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.33	GO:0005737	cytoplasm

sp|P04554|PRM2_HUMAN
Protamine-2
Search

PRM2

0.97	Protamine-2

0.83	GO:0007286	spermatid development
0.75	GO:0006323	DNA packaging
0.55	GO:0007275	multicellular organism development
0.50	GO:0006997	nucleus organization
0.37	GO:0060330	regulation of response to interferon-gamma
0.37	GO:0046426	negative regulation of JAK-STAT cascade
0.36	GO:0001959	regulation of cytokine-mediated signaling pathway
0.35	GO:0016567	protein ubiquitination
0.34	GO:0035556	intracellular signal transduction
0.34	GO:0006325	chromatin organization

0.55	GO:0003677	DNA binding
0.51	GO:0046870	cadmium ion binding
0.41	GO:0008270	zinc ion binding
0.36	GO:0005515	protein binding

0.58	GO:0000786	nucleosome
0.50	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.34	GO:0005737	cytoplasm

sp|P04626|ERBB2_HUMAN
Receptor tyrosine-protein kinase erbB-2
Search

ERBB2

0.65	Receptor protein-tyrosine kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.76	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.63	GO:0023014	signal transduction by protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.59	GO:0033088	negative regulation of immature T cell proliferation in thymus
0.58	GO:0090314	positive regulation of protein targeting to membrane
0.58	GO:0071364	cellular response to epidermal growth factor stimulus
0.58	GO:0045945	positive regulation of transcription by RNA polymerase III
0.58	GO:0042552	myelination
0.58	GO:0007422	peripheral nervous system development

0.83	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.79	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.59	GO:0001042	RNA polymerase I core binding
0.55	GO:0019903	protein phosphatase binding
0.55	GO:0008022	protein C-terminus binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0019838	growth factor binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding

0.55	GO:0043209	myelin sheath
0.54	GO:0016323	basolateral plasma membrane
0.54	GO:0016324	apical plasma membrane
0.53	GO:0043235	receptor complex
0.52	GO:0010008	endosome membrane
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.40	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0045178	basal part of cell
0.35	GO:0005902	microvillus

0.83	EC:2.7.10	GO:0004716
0.36	KEGG:R04545	GO:0046934

sp|P04628|WNT1_HUMAN
Proto-oncogene Wnt-1
Search

WNT1

0.86	Proto-oncogene Wnt-1

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.62	GO:0036520	astrocyte-dopaminergic neuron signaling
0.62	GO:0061184	positive regulation of dermatome development
0.61	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
0.60	GO:0030579	ubiquitin-dependent SMAD protein catabolic process
0.60	GO:0060061	Spemann organizer formation
0.60	GO:0010592	positive regulation of lamellipodium assembly
0.59	GO:0090344	negative regulation of cell aging
0.59	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.73	GO:0005102	receptor binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.53	GO:0030545	receptor regulator activity
0.53	GO:0019904	protein domain specific binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.52	GO:0009986	cell surface
0.45	GO:0005615	extracellular space
0.40	GO:0005737	cytoplasm
0.36	GO:1990909	Wnt signalosome
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:1903561	extracellular vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0097708	intracellular vesicle

0.33

GO:0004222

sp|P04629|NTRK1_HUMAN
High affinity nerve growth factor receptor
Search

NTRK1

0.65	Tyrosine-protein kinase receptor

0.77	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.76	GO:0038179	neurotrophin signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0061368	behavioral response to formalin induced pain
0.59	GO:0060385	axonogenesis involved in innervation
0.58	GO:1990090	cellular response to nerve growth factor stimulus
0.57	GO:0048485	sympathetic nervous system development
0.56	GO:0046579	positive regulation of Ras protein signal transduction
0.56	GO:0051965	positive regulation of synapse assembly
0.56	GO:0042490	mechanoreceptor differentiation

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.78	GO:0005030	neurotrophin receptor activity
0.60	GO:0048406	nerve growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042803	protein homodimerization activity
0.35	GO:0002039	p53 binding
0.35	GO:0042289	MHC class II protein binding

0.65	GO:0005887	integral component of plasma membrane
0.53	GO:0043235	receptor complex
0.53	GO:0005770	late endosome
0.53	GO:0005769	early endosome
0.53	GO:0030424	axon
0.51	GO:0009986	cell surface

0.80

GO:0004714

sp|P04632|CPNS1_HUMAN
Calpain small subunit 1
Search

CAPNS1

0.97	Calpain small subunit 1

0.45	GO:0006508	proteolysis
0.38	GO:0022617	extracellular matrix disassembly
0.36	GO:0070268	cornification
0.36	GO:0016241	regulation of macroautophagy
0.35	GO:0008284	positive regulation of cell proliferation

0.68	GO:0005509	calcium ion binding
0.56	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.37	GO:0005515	protein binding

0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane

sp|P04637|P53_HUMAN
Cellular tumor antigen p53
Search

TP53

0.84	Cellular tumor antigen p53

0.78	GO:0006915	apoptotic process
0.74	GO:0051262	protein tetramerization
0.67	GO:0007049	cell cycle
0.61	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.61	GO:0000733	DNA strand renaturation
0.59	GO:0030308	negative regulation of cell growth
0.58	GO:0007569	cell aging
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0072717	cellular response to actinomycin D
0.57	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001084	transcription factor activity, TFIID-class binding
0.55	GO:0001094	TFIID-class transcription factor binding
0.55	GO:0002039	p53 binding
0.55	GO:0035035	histone acetyltransferase binding
0.54	GO:0051721	protein phosphatase 2A binding
0.54	GO:0097718	disordered domain specific binding
0.54	GO:1990837	sequence-specific double-stranded DNA binding
0.54	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.51	GO:0005667	transcription factor complex
0.49	GO:0000785	chromatin
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0005737	cytoplasm
0.45	GO:0012505	endomembrane system
0.42	GO:0005657	replication fork
0.36	GO:0035861	site of double-strand break
0.33	GO:0005886	plasma membrane

sp|P04731|MT1A_HUMAN
Metallothionein-1A
Search

0.76	Metallothionein-II, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.48	GO:0071276	cellular response to cadmium ion
0.48	GO:0036018	cellular response to erythropoietin
0.43	GO:0036015	response to interleukin-3
0.40	GO:0035690	cellular response to drug
0.39	GO:0046688	response to copper ion
0.38	GO:0007263	nitric oxide mediated signal transduction
0.38	GO:0097501	stress response to metal ion
0.37	GO:0006875	cellular metal ion homeostasis

0.54	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.34	GO:0005764	lysosome
0.30	GO:0016021	integral component of membrane

sp|P04732|MT1E_HUMAN
Metallothionein-1E
Search

0.74	Metallothionein-II, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.48	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.43	GO:0010273	detoxification of copper ion
0.42	GO:0007263	nitric oxide mediated signal transduction
0.42	GO:0006882	cellular zinc ion homeostasis
0.41	GO:0035690	cellular response to drug
0.40	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.54	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.37	GO:0005764	lysosome
0.30	GO:0016021	integral component of membrane

sp|P04733|MT1F_HUMAN
Metallothionein-1F
Search

0.75	Metallothionein-I, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.48	GO:0071276	cellular response to cadmium ion
0.45	GO:0036015	response to interleukin-3
0.43	GO:0010273	detoxification of copper ion
0.43	GO:0007263	nitric oxide mediated signal transduction
0.42	GO:0006882	cellular zinc ion homeostasis
0.41	GO:0035690	cellular response to drug
0.40	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.36	GO:0008144	drug binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.37	GO:0005764	lysosome

sp|P04745|AMY1_HUMAN
Alpha-amylase 1
Search

0.43	Pancreatic alpha-amylase

0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0007586	digestion
0.36	GO:1901575	organic substance catabolic process

0.81	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.80	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding
0.41	GO:0031404	chloride ion binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.42	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.2.1.1

GO:0004556

sp|P04746|AMYP_HUMAN
Pancreatic alpha-amylase
Search

0.43	Pancreatic alpha-amylase

0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0007586	digestion
0.36	GO:1901575	organic substance catabolic process

0.81	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.80	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding
0.41	GO:0031404	chloride ion binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.41	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.2.1.1

GO:0004556

sp|P04792|HSPB1_HUMAN
Heat shock protein beta-1
Search

HSPB1

0.90	LOW QUALITY PROTEIN: heat shock protein beta-1

0.85	GO:0099641	anterograde axonal protein transport
0.80	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
0.79	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.78	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.77	GO:0032731	positive regulation of interleukin-1 beta production
0.75	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.73	GO:0045766	positive regulation of angiogenesis
0.72	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.72	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.71	GO:0061077	chaperone-mediated protein folding

0.82	GO:0008426	protein kinase C inhibitor activity
0.78	GO:0044183	protein binding involved in protein folding
0.76	GO:0005080	protein kinase C binding
0.69	GO:0042803	protein homodimerization activity
0.44	GO:0043130	ubiquitin binding
0.40	GO:0005212	structural constituent of eye lens
0.37	GO:0003723	RNA binding
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0046872	metal ion binding

0.77	GO:1904115	axon cytoplasm
0.73	GO:0030018	Z disc
0.61	GO:0005634	nucleus
0.51	GO:0005886	plasma membrane
0.50	GO:0005819	spindle
0.42	GO:0031012	extracellular matrix
0.42	GO:1905369	endopeptidase complex
0.42	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome
0.40	GO:0070013	intracellular organelle lumen

0.34

EC:3.1.4.17

GO:0004114

sp|P04798|CP1A1_HUMAN
Cytochrome P450 1A1
Search

sp|P04808|REL1_HUMAN
Prorelaxin H1
Search

0.96	Prorelaxin

0.76	GO:0010469	regulation of receptor activity
0.55	GO:0007565	female pregnancy
0.55	GO:0030819	positive regulation of cAMP biosynthetic process
0.53	GO:0045766	positive regulation of angiogenesis
0.48	GO:0010628	positive regulation of gene expression
0.46	GO:0050790	regulation of catalytic activity
0.45	GO:2000344	positive regulation of acrosome reaction
0.44	GO:0001832	blastocyst growth
0.44	GO:0001556	oocyte maturation
0.44	GO:0007165	signal transduction

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P04818|TYSY_HUMAN
Thymidylate synthase
Search

TYMS

0.46	Thymidylate synthetase

0.78	GO:0006231	dTMP biosynthetic process
0.63	GO:0032259	methylation
0.54	GO:0046683	response to organophosphorus
0.51	GO:0017148	negative regulation of translation
0.50	GO:0035999	tetrahydrofolate interconversion
0.45	GO:0060041	retina development in camera-type eye
0.43	GO:0019088	immortalization of host cell by virus
0.42	GO:0060574	intestinal epithelial cell maturation
0.42	GO:0033189	response to vitamin A
0.42	GO:0051593	response to folic acid

0.80	GO:0004799	thymidylate synthase activity
0.57	GO:1990825	sequence-specific mRNA binding
0.57	GO:0000900	translation repressor activity, nucleic acid binding
0.40	GO:0005542	folic acid binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0048037	cofactor binding
0.35	GO:1901265	nucleoside phosphate binding

0.51	GO:0005759	mitochondrial matrix
0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.45	GO:0005634	nucleus
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.80	EC:2.1.1.45	GO:0004799
0.80	KEGG:R02101	GO:0004799

sp|P04839|CY24B_HUMAN
Cytochrome b-245 heavy chain
Search

CYBB

0.96	Cytochrome b-245 heavy chain

0.63	GO:0042554	superoxide anion generation
0.59	GO:0045730	respiratory burst
0.54	GO:0045087	innate immune response
0.53	GO:0050665	hydrogen peroxide biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0006954	inflammatory response
0.45	GO:0006091	generation of precursor metabolites and energy
0.44	GO:1904845	cellular response to L-glutamine
0.44	GO:1904044	response to aldosterone
0.43	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway

0.65	GO:0016175	superoxide-generating NADPH oxidase activity
0.52	GO:0046982	protein heterodimerization activity
0.48	GO:0050660	flavin adenine dinucleotide binding
0.46	GO:0020037	heme binding
0.46	GO:0009055	electron transfer activity
0.39	GO:0022832	voltage-gated channel activity
0.38	GO:0022839	ion gated channel activity
0.38	GO:0008381	mechanosensitive ion channel activity
0.37	GO:0016174	NAD(P)H oxidase activity
0.37	GO:0048365	Rac GTPase binding

0.60	GO:0043020	NADPH oxidase complex
0.51	GO:0045335	phagocytic vesicle
0.42	GO:0005739	mitochondrion
0.41	GO:0005791	rough endoplasmic reticulum
0.41	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0043025	neuronal cell body
0.41	GO:0097447	dendritic tree
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005635	nuclear envelope
0.39	GO:0005794	Golgi apparatus

0.65

EC:1.6.3

GO:0016175

sp|P04843|RPN1_HUMAN
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Search

RPN1

0.69	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

0.74	GO:0006486	protein glycosylation
0.57	GO:0018196	peptidyl-asparagine modification
0.33	GO:0042886	amide transport
0.33	GO:0071702	organic substance transport

0.84	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.53	GO:0005791	rough endoplasmic reticulum
0.47	GO:0005829	cytosol
0.43	GO:1990234	transferase complex
0.41	GO:0042470	melanosome
0.37	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.1.119

GO:0004579

sp|P04844|RPN2_HUMAN
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Search

RPN2

0.81	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

0.80	GO:0006487	protein N-linked glycosylation
0.39	GO:0007568	aging
0.38	GO:0042493	response to drug
0.36	GO:0018196	peptidyl-asparagine modification

0.49	GO:0016740	transferase activity
0.38	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding

0.82	GO:0008250	oligosaccharyltransferase complex
0.41	GO:0000421	autophagosome membrane
0.40	GO:0005791	rough endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0016740

sp|P04899|GNAI2_HUMAN
Guanine nucleotide-binding protein G(i) subunit alpha-2
Search

GNAI2

0.93	Guanine nucleotide binding protein alpha inhibiting 2

0.81	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.51	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.49	GO:0008283	cell proliferation
0.48	GO:0001973	adenosine receptor signaling pathway
0.47	GO:0007214	gamma-aminobutyric acid signaling pathway
0.46	GO:0051301	cell division
0.38	GO:0050805	negative regulation of synaptic transmission
0.38	GO:0007049	cell cycle
0.37	GO:0000186	activation of MAPKK activity
0.37	GO:0051924	regulation of calcium ion transport

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0001664	G-protein coupled receptor binding
0.35	GO:0046872	metal ion binding

0.53	GO:0030496	midbody
0.51	GO:0005813	centrosome
0.50	GO:0030425	dendrite
0.50	GO:0044297	cell body
0.47	GO:1905360	GTPase complex
0.47	GO:0005654	nucleoplasm
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0005829	cytosol
0.42	GO:0098797	plasma membrane protein complex
0.37	GO:0045121	membrane raft

sp|P04908|H2A1B_HUMAN
Histone H2A type 1-B/E
Search

0.97	Histone H2A type 1-I

0.58	GO:0006342	chromatin silencing
0.50	GO:0031498	chromatin disassembly
0.50	GO:0032986	protein-DNA complex disassembly
0.50	GO:0070914	UV-damage excision repair
0.47	GO:0008285	negative regulation of cell proliferation
0.47	GO:0034728	nucleosome organization
0.35	GO:0031497	chromatin assembly
0.35	GO:0065004	protein-DNA complex assembly
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.37	GO:0019899	enzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.53	GO:0031974	membrane-enclosed lumen
0.41	GO:0070062	extracellular exosome

sp|P04920|B3A2_HUMAN
Anion exchange protein 2
Search

SLC4A2

0.65	Anion exchange protein 2

0.69	GO:0015698	inorganic anion transport
0.69	GO:0098656	anion transmembrane transport
0.49	GO:0015701	bicarbonate transport
0.48	GO:0051453	regulation of intracellular pH
0.46	GO:0035725	sodium ion transmembrane transport
0.38	GO:0048565	digestive tract development
0.38	GO:0007283	spermatogenesis

0.82	GO:0005452	inorganic anion exchanger activity
0.50	GO:0008510	sodium:bicarbonate symporter activity
0.49	GO:0015301	anion:anion antiporter activity
0.37	GO:0019899	enzyme binding
0.36	GO:0015108	chloride transmembrane transporter activity
0.35	GO:0015280	ligand-gated sodium channel activity

0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0016323	basolateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.37	GO:0005925	focal adhesion

sp|P04921|GLPC_HUMAN
Glycophorin-C
Search

GYPC

0.96	Glycophorin C (Gerbich blood group)

0.67	GO:0071205	protein localization to juxtaparanode region of axon
0.43	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.43	GO:0008037	cell recognition
0.41	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.40	GO:0042297	vocal learning
0.40	GO:0071109	superior temporal gyrus development
0.40	GO:0071625	vocalization behavior
0.40	GO:0035176	social behavior
0.40	GO:0021794	thalamus development
0.39	GO:0021756	striatum development

0.42	GO:0050839	cell adhesion molecule binding
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0005102	receptor binding
0.38	GO:0004872	receptor activity
0.37	GO:0019899	enzyme binding
0.34	GO:0005509	calcium ion binding

0.48	GO:0030863	cortical cytoskeleton
0.43	GO:0005913	cell-cell adherens junction
0.41	GO:0005887	integral component of plasma membrane
0.40	GO:0030673	axolemma
0.39	GO:0005769	early endosome
0.38	GO:0034705	potassium channel complex
0.38	GO:0009986	cell surface
0.37	GO:0005794	Golgi apparatus
0.36	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0033010	paranodal junction

sp|P05000|IFNW1_HUMAN
Interferon omega-1
Search

0.92	Ovine interferon alpha

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.56	GO:0002323	natural killer cell activation involved in immune response
0.56	GO:0042100	B cell proliferation
0.55	GO:0002286	T cell activation involved in immune response
0.55	GO:0043330	response to exogenous dsRNA
0.54	GO:0030183	B cell differentiation
0.53	GO:0002250	adaptive immune response
0.53	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding
0.38	GO:0005179	hormone activity

0.73	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P05013|IFNA6_HUMAN
Interferon alpha-6
Search

0.92	Interferon alpha

0.77	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.57	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.57	GO:0002323	natural killer cell activation involved in immune response
0.56	GO:0042100	B cell proliferation
0.55	GO:0002286	T cell activation involved in immune response
0.55	GO:0043330	response to exogenous dsRNA
0.55	GO:0030183	B cell differentiation
0.53	GO:0002250	adaptive immune response
0.53	GO:0006959	humoral immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

sp|P05014|IFNA4_HUMAN
Interferon alpha-4
Search

0.91	Interferon alpha-N

0.78	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.56	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.56	GO:0002323	natural killer cell activation involved in immune response
0.55	GO:0042100	B cell proliferation
0.55	GO:0002286	T cell activation involved in immune response
0.54	GO:0043330	response to exogenous dsRNA
0.54	GO:0030183	B cell differentiation
0.52	GO:0002250	adaptive immune response
0.52	GO:0006959	humoral immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.49	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

sp|P05015|IFN16_HUMAN
Interferon alpha-16
Search

0.92	Interferon alpha-N

0.78	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.56	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.56	GO:0002323	natural killer cell activation involved in immune response
0.55	GO:0042100	B cell proliferation
0.54	GO:0002286	T cell activation involved in immune response
0.54	GO:0043330	response to exogenous dsRNA
0.54	GO:0030183	B cell differentiation
0.52	GO:0002250	adaptive immune response
0.52	GO:0006959	humoral immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.49	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

sp|P05019|IGF1_HUMAN
Insulin-like growth factor I
Search

IGF1

0.88	IGF-I splicing variant class 1

0.76	GO:0010469	regulation of receptor activity
0.59	GO:0045725	positive regulation of glycogen biosynthetic process
0.59	GO:0048009	insulin-like growth factor receptor signaling pathway
0.58	GO:0046326	positive regulation of glucose import
0.57	GO:1904073	regulation of trophectodermal cell proliferation
0.56	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process
0.56	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development
0.56	GO:2001234	negative regulation of apoptotic signaling pathway
0.56	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
0.56	GO:0035630	bone mineralization involved in bone maturation

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.59	GO:0005159	insulin-like growth factor receptor binding
0.54	GO:0005158	insulin receptor binding
0.53	GO:0005178	integrin binding
0.34	GO:0043539	protein serine/threonine kinase activator activity
0.34	GO:0005496	steroid binding

0.73	GO:0005615	extracellular space
0.60	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.55	GO:0036454	growth factor complex
0.45	GO:0070382	exocytic vesicle
0.39	GO:0005829	cytosol
0.37	GO:0031091	platelet alpha granule
0.36	GO:0034774	secretory granule lumen
0.35	GO:0005614	interstitial matrix
0.34	GO:0043025	neuronal cell body
0.30	GO:0031224	intrinsic component of membrane

sp|P05023|AT1A1_HUMAN
Sodium/potassium-transporting ATPase subunit alpha-1
Search

ATP1A1

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.54	GO:1903416	response to glycoside
0.53	GO:0006883	cellular sodium ion homeostasis
0.53	GO:0086009	membrane repolarization
0.53	GO:0031947	negative regulation of glucocorticoid biosynthetic process
0.52	GO:0045989	positive regulation of striated muscle contraction
0.52	GO:0045822	negative regulation of heart contraction

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0046872	metal ion binding
0.53	GO:1990239	steroid hormone binding
0.47	GO:0051087	chaperone binding
0.44	GO:0016791	phosphatase activity
0.38	GO:0030506	ankyrin binding

0.53	GO:0042383	sarcolemma
0.51	GO:0005890	sodium:potassium-exchanging ATPase complex
0.49	GO:0014069	postsynaptic density
0.49	GO:0043209	myelin sheath
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0016324	apical plasma membrane
0.41	GO:0043234	protein complex
0.38	GO:0014704	intercalated disc
0.37	GO:0005901	caveola
0.37	GO:0031410	cytoplasmic vesicle

0.85

GO:0005391

sp|P05026|AT1B1_HUMAN
Sodium/potassium-transporting ATPase subunit beta-1
Search

ATP1B1

0.79	Sodium/potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.61	GO:1903281	positive regulation of calcium:sodium antiporter activity
0.61	GO:1903288	positive regulation of potassium ion import
0.61	GO:1903275	positive regulation of sodium ion export
0.61	GO:1903276	regulation of sodium ion export across plasma membrane
0.60	GO:0055119	relaxation of cardiac muscle
0.60	GO:0006883	cellular sodium ion homeostasis
0.60	GO:0086009	membrane repolarization
0.60	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.58	GO:0005391	sodium:potassium-exchanging ATPase activity
0.58	GO:0051117	ATPase binding
0.56	GO:0008022	protein C-terminus binding
0.55	GO:0001671	ATPase activator activity
0.55	GO:0031402	sodium ion binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0030955	potassium ion binding
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.58	GO:0014704	intercalated disc
0.57	GO:0042383	sarcolemma
0.56	GO:0043209	myelin sheath
0.56	GO:0016323	basolateral plasma membrane
0.55	GO:0016324	apical plasma membrane
0.41	GO:0005901	caveola
0.37	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome

0.58

GO:0005391

sp|P05060|SCG1_HUMAN
Secretogranin-1
Search

CHGB

0.96	Chromogranin B

0.38	GO:0043687	post-translational protein modification
0.37	GO:0010469	regulation of receptor activity
0.36	GO:0006887	exocytosis

0.38

GO:0005179

hormone activity

0.81	GO:0030141	secretory granule
0.40	GO:0005576	extracellular region
0.39	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0030658	transport vesicle membrane

sp|P05062|ALDOB_HUMAN
Fructose-bisphosphate aldolase B
Search

ALDOB

0.54	Fructose-bisphosphate aldolase B

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.57	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.56	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.56	GO:0006000	fructose metabolic process
0.55	GO:0032781	positive regulation of ATPase activity
0.41	GO:0055114	oxidation-reduction process
0.36	GO:0001889	liver development

0.79	GO:0004332	fructose-bisphosphate aldolase activity
0.63	GO:0061609	fructose-1-phosphate aldolase activity
0.61	GO:0070061	fructose binding
0.58	GO:0051117	ATPase binding
0.52	GO:0042802	identical protein binding
0.51	GO:0008092	cytoskeletal protein binding
0.35	GO:0031210	phosphatidylcholine binding

0.59	GO:0034451	centriolar satellite
0.38	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.36	GO:0030868	smooth endoplasmic reticulum membrane
0.35	GO:0030867	rough endoplasmic reticulum membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005764	lysosome
0.33	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:4.1.2.13

GO:0004332

sp|P05067|A4_HUMAN
Amyloid beta A4 protein
Search

APP

0.92	Testicular tissue protein Li 2

0.74	GO:0007399	nervous system development
0.71	GO:0010951	negative regulation of endopeptidase activity
0.59	GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis
0.58	GO:1905908	positive regulation of amyloid fibril formation
0.58	GO:0032640	tumor necrosis factor production
0.58	GO:0150003	regulation of spontaneous synaptic transmission
0.58	GO:0007176	regulation of epidermal growth factor-activated receptor activity
0.57	GO:1903980	positive regulation of microglial cell activation
0.57	GO:1990535	neuron projection maintenance
0.57	GO:1900272	negative regulation of long-term synaptic potentiation

0.81	GO:0008201	heparin binding
0.73	GO:0004867	serine-type endopeptidase inhibitor activity
0.58	GO:0051425	PTB domain binding
0.57	GO:0046914	transition metal ion binding
0.49	GO:0042802	identical protein binding
0.49	GO:0005102	receptor binding
0.48	GO:0019899	enzyme binding
0.42	GO:0003677	DNA binding
0.41	GO:0016504	peptidase activator activity
0.37	GO:0097645	amylin binding

0.56	GO:0035253	ciliary rootlet
0.56	GO:0005790	smooth endoplasmic reticulum
0.56	GO:0005641	nuclear envelope lumen
0.55	GO:0043198	dendritic shaft
0.54	GO:0031594	neuromuscular junction
0.54	GO:0043197	dendritic spine
0.54	GO:0051233	spindle midzone
0.54	GO:0030424	axon
0.52	GO:0045177	apical part of cell
0.52	GO:0098589	membrane region

0.34

GO:0008233

sp|P05089|ARGI1_HUMAN
Arginase-1
Search

ARG1

0.57	Arginase-2, mitochondrial

0.85	GO:0000050	urea cycle
0.71	GO:0006525	arginine metabolic process
0.63	GO:0002829	negative regulation of type 2 immune response
0.62	GO:0042130	negative regulation of T cell proliferation
0.60	GO:0002831	regulation of response to biotic stimulus
0.59	GO:0001818	negative regulation of cytokine production
0.58	GO:0070960	positive regulation of neutrophil mediated cytotoxicity
0.57	GO:0060331	negative regulation of response to interferon-gamma
0.57	GO:0032101	regulation of response to external stimulus
0.57	GO:0043900	regulation of multi-organism process

0.83	GO:0004053	arginase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0003933	GTP cyclohydrolase activity
0.35	GO:0050998	nitric-oxide synthase binding

0.49	GO:0005615	extracellular space
0.42	GO:0005739	mitochondrion
0.38	GO:0043025	neuronal cell body
0.37	GO:0043005	neuron projection
0.37	GO:0031968	organelle outer membrane
0.36	GO:1903561	extracellular vesicle
0.36	GO:0035580	specific granule lumen
0.36	GO:0035578	azurophil granule lumen
0.34	GO:0005634	nucleus
0.34	GO:0005829	cytosol

0.83

EC:3.5.3.1

GO:0004053

sp|P05090|APOD_HUMAN
Apolipoprotein D
Search

APOD

0.88	Apolipoprotein D

0.79	GO:0007568	aging
0.72	GO:0006869	lipid transport
0.65	GO:0034443	negative regulation of lipoprotein oxidation
0.65	GO:0060587	regulation of lipoprotein lipid oxidation
0.64	GO:2000098	negative regulation of smooth muscle cell-matrix adhesion
0.64	GO:2000405	negative regulation of T cell migration
0.63	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.63	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.62	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.62	GO:0051895	negative regulation of focal adhesion assembly

0.71	GO:0008289	lipid binding
0.58	GO:0043178	alcohol binding
0.45	GO:0031409	pigment binding
0.38	GO:0097159	organic cyclic compound binding
0.36	GO:0004864	protein phosphatase inhibitor activity
0.35	GO:0005319	lipid transporter activity
0.34	GO:0016301	kinase activity
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.34	GO:0005515	protein binding
0.33	GO:0008242	omega peptidase activity

0.56	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005615	extracellular space
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.49	GO:0022626	cytosolic ribosome
0.46	GO:0005783	endoplasmic reticulum
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.34

EC:1.3.99.3

GO:0003995

sp|P05091|ALDH2_HUMAN
Aldehyde dehydrogenase, mitochondrial
Search

ALDH2

0.39	Mitochondrial aldehyde dehydrogenase 2

0.52	GO:0055114	oxidation-reduction process
0.46	GO:0006068	ethanol catabolic process
0.36	GO:0033574	response to testosterone
0.36	GO:0055093	response to hyperoxia
0.36	GO:0032570	response to progesterone
0.36	GO:0035094	response to nicotine
0.36	GO:0071398	cellular response to fatty acid
0.36	GO:0032355	response to estradiol
0.36	GO:0001889	liver development
0.35	GO:0032496	response to lipopolysaccharide

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.39	GO:0051287	NAD binding
0.35	GO:0005515	protein binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0043168	anion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.45	GO:0005739	mitochondrion
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome

0.69

EC:1.2.1

GO:0016620

sp|P05093|CP17A_HUMAN
Steroid 17-alpha-hydroxylase/17,20 lyase
Search

CYP17A1

0.94	steroid 17-alpha-hydroxylase/17,20 lyase precursor

0.71	GO:0006694	steroid biosynthetic process
0.68	GO:0042448	progesterone metabolic process
0.64	GO:0007548	sex differentiation
0.60	GO:0042446	hormone biosynthetic process
0.59	GO:0008211	glucocorticoid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0042181	ketone biosynthetic process
0.38	GO:0008209	androgen metabolic process
0.36	GO:1901615	organic hydroxy compound metabolic process
0.36	GO:0018879	biphenyl metabolic process

0.83	GO:0004508	steroid 17-alpha-monooxygenase activity
0.83	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.35	GO:0019825	oxygen binding
0.32	GO:0004796	thromboxane-A synthase activity
0.32	GO:0070330	aromatase activity

0.54	GO:0043025	neuronal cell body
0.54	GO:0030424	axon
0.45	GO:0005739	mitochondrion
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.83	EC:1.14.99.9	GO:0004508
0.32	KEGG:R02268	GO:0004796

sp|P05106|ITB3_HUMAN
Integrin beta-3
Search

ITGB3

0.68	Integrin beta

0.86	GO:0060055	angiogenesis involved in wound healing
0.85	GO:0070527	platelet aggregation
0.85	GO:0007044	cell-substrate junction assembly
0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.79	GO:0030334	regulation of cell migration
0.56	GO:0033690	positive regulation of osteoblast proliferation
0.56	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.55	GO:0043277	apoptotic cell clearance
0.55	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading

0.65	GO:0004872	receptor activity
0.56	GO:0005178	integrin binding
0.54	GO:0005080	protein kinase C binding
0.42	GO:0038132	neuregulin binding
0.42	GO:0042802	identical protein binding
0.42	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.42	GO:0019960	C-X3-C chemokine binding
0.41	GO:0031994	insulin-like growth factor I binding
0.41	GO:0001968	fibronectin binding
0.41	GO:0017134	fibroblast growth factor binding

0.81	GO:0008305	integrin complex
0.59	GO:0035866	alphav-beta3 integrin-PKCalpha complex
0.58	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.54	GO:0009897	external side of plasma membrane
0.52	GO:0016324	apical plasma membrane
0.42	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.42	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.41	GO:0031258	lamellipodium membrane
0.41	GO:0031528	microvillus membrane
0.41	GO:0031527	filopodium membrane

0.40

EC:5.3.4.1

GO:0003756

sp|P05107|ITB2_HUMAN
Integrin beta-2
Search

ITGB2

0.67	Integrin beta

0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0034113	heterotypic cell-cell adhesion
0.61	GO:0007159	leukocyte cell-cell adhesion
0.60	GO:0043315	positive regulation of neutrophil degranulation
0.60	GO:0043113	receptor clustering
0.58	GO:0050900	leukocyte migration
0.58	GO:0032930	positive regulation of superoxide anion generation
0.56	GO:0035987	endodermal cell differentiation
0.54	GO:0050730	regulation of peptidyl-tyrosine phosphorylation

0.65	GO:0004872	receptor activity
0.57	GO:0050839	cell adhesion molecule binding
0.53	GO:0019901	protein kinase binding
0.52	GO:0031072	heat shock protein binding
0.46	GO:0004871	signal transducer activity
0.41	GO:0001851	complement component C3b binding
0.39	GO:0001540	amyloid-beta binding
0.38	GO:0032403	protein complex binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0046872	metal ion binding

0.81	GO:0008305	integrin complex
0.55	GO:0044853	plasma membrane raft
0.54	GO:0009986	cell surface
0.51	GO:0099568	cytoplasmic region
0.39	GO:0070062	extracellular exosome
0.37	GO:0101003	ficolin-1-rich granule membrane
0.37	GO:0035579	specific granule membrane
0.37	GO:0070821	tertiary granule membrane
0.35	GO:0098552	side of membrane

sp|P05108|CP11A_HUMAN
Cholesterol side-chain cleavage enzyme, mitochondrial
Search

CYP11A1

0.96	Cholesterol side-chain cleavage enzyme, mitochondrial

0.86	GO:0006700	C21-steroid hormone biosynthetic process
0.83	GO:0008203	cholesterol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.39	GO:0042359	vitamin D metabolic process
0.37	GO:0060429	epithelium development
0.37	GO:0031116	positive regulation of microtubule polymerization
0.37	GO:0033595	response to genistein
0.37	GO:0018879	biphenyl metabolic process
0.37	GO:0018963	phthalate metabolic process
0.36	GO:0018894	dibenzo-p-dioxin metabolic process

0.86	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0015485	cholesterol binding
0.35	GO:0004507	steroid 11-beta-monooxygenase activity
0.34	GO:0005515	protein binding

0.62	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.36	GO:0043204	perikaryon
0.35	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:1.14.15.6

GO:0008386

sp|P05109|S10A8_HUMAN
Protein S100-A8
Search

S100A8

0.93	S100 calcium binding protein A8

0.82	GO:0050727	regulation of inflammatory response
0.79	GO:0045087	innate immune response
0.79	GO:0070488	neutrophil aggregation
0.77	GO:0018119	peptidyl-cysteine S-nitrosylation
0.76	GO:0002523	leukocyte migration involved in inflammatory response
0.72	GO:0030593	neutrophil chemotaxis
0.72	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.72	GO:0014002	astrocyte development
0.72	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.68	GO:0032103	positive regulation of response to external stimulus

0.87	GO:0035662	Toll-like receptor 4 binding
0.87	GO:0050544	arachidonic acid binding
0.86	GO:0050786	RAGE receptor binding
0.74	GO:0008017	microtubule binding
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding

0.66	GO:0045111	intermediate filament cytoskeleton
0.62	GO:0005615	extracellular space
0.59	GO:0005829	cytosol

sp|P05111|INHA_HUMAN
Inhibin alpha chain
Search

INHA

0.96	Inhibin alpha subunit

0.75	GO:0010469	regulation of receptor activity
0.71	GO:0042541	hemoglobin biosynthetic process
0.60	GO:0042127	regulation of cell proliferation
0.57	GO:0051726	regulation of cell cycle
0.53	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.53	GO:0060395	SMAD protein signal transduction
0.53	GO:0030509	BMP signaling pathway
0.50	GO:0043408	regulation of MAPK cascade
0.48	GO:0048468	cell development
0.48	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.73	GO:0005179	hormone activity
0.53	GO:0005160	transforming growth factor beta receptor binding
0.51	GO:0005125	cytokine activity
0.44	GO:0034711	inhibin binding
0.39	GO:0046982	protein heterodimerization activity

0.70	GO:0043512	inhibin A complex
0.70	GO:0034673	inhibin-betaglycan-ActRII complex
0.45	GO:0043513	inhibin B complex
0.42	GO:0001917	photoreceptor inner segment
0.42	GO:0001750	photoreceptor outer segment
0.41	GO:0043025	neuronal cell body
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P05112|IL4_HUMAN
Interleukin-4
Search

IL4

0.93	Interleukin-4

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.72	GO:0042113	B cell activation
0.57	GO:1903660	negative regulation of complement-dependent cytotoxicity
0.56	GO:0032736	positive regulation of interleukin-13 production
0.55	GO:0043011	myeloid dendritic cell differentiation
0.55	GO:2000352	negative regulation of endothelial cell apoptotic process
0.54	GO:1902105	regulation of leukocyte differentiation
0.54	GO:0010633	negative regulation of epithelial cell migration
0.53	GO:0002440	production of molecular mediator of immune response

0.86	GO:0005136	interleukin-4 receptor binding
0.78	GO:0008083	growth factor activity
0.69	GO:0005125	cytokine activity

0.66

GO:0005576

extracellular region

sp|P05113|IL5_HUMAN
Interleukin-5
Search

IL5

0.96	Interleukin-5

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.72	GO:0051024	positive regulation of immunoglobulin secretion
0.71	GO:0071803	positive regulation of podosome assembly
0.66	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.65	GO:0051091	positive regulation of DNA binding transcription factor activity
0.59	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0045645	positive regulation of eosinophil differentiation
0.46	GO:0030890	positive regulation of B cell proliferation
0.46	GO:0046427	positive regulation of JAK-STAT cascade

0.87	GO:0005137	interleukin-5 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.38	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.38	GO:0004713	protein tyrosine kinase activity

0.73	GO:0005615	extracellular space
0.33	GO:0005622	intracellular

0.38

GO:0004713

sp|P05114|HMGN1_HUMAN
Non-histone chromosomal protein HMG-14
Search

HMGN1

0.93	Non-histone chromosomal protein HMG-14

0.44	GO:0048597	post-embryonic camera-type eye morphogenesis
0.44	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair
0.44	GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity
0.43	GO:0010225	response to UV-C
0.43	GO:0040034	regulation of development, heterochronic
0.43	GO:0010224	response to UV-B
0.42	GO:0050678	regulation of epithelial cell proliferation
0.41	GO:0006283	transcription-coupled nucleotide-excision repair
0.40	GO:0006325	chromatin organization
0.39	GO:0006357	regulation of transcription by RNA polymerase II

0.85	GO:0031492	nucleosomal DNA binding
0.34	GO:0005515	protein binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0005737	cytoplasm

sp|P05120|PAI2_HUMAN
Plasminogen activator inhibitor 2
Search

SERPINB2

0.86	Leukocyte elastase inhibitor

0.69	GO:0010951	negative regulation of endopeptidase activity
0.67	GO:0043066	negative regulation of apoptotic process
0.40	GO:0042060	wound healing
0.38	GO:0090362	positive regulation of platelet-derived growth factor production
0.38	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.38	GO:0072126	positive regulation of glomerular mesangial cell proliferation
0.37	GO:0032914	positive regulation of transforming growth factor beta1 production
0.37	GO:0035722	interleukin-12-mediated signaling pathway
0.37	GO:0002448	mast cell mediated immunity
0.37	GO:0033668	negative regulation by symbiont of host apoptotic process

0.71	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.36	GO:0002020	protease binding

0.73	GO:0005615	extracellular space
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.35	GO:0005794	Golgi apparatus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005885	Arp2/3 protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P05121|PAI1_HUMAN
Plasminogen activator inhibitor 1
Search

SERPINE1

0.93	Clade E serpine peptidase inhibitor

0.66	GO:0010757	negative regulation of plasminogen activation
0.63	GO:0035491	positive regulation of leukotriene production involved in inflammatory response
0.63	GO:1901331	positive regulation of odontoblast differentiation
0.63	GO:0061044	negative regulation of vascular wound healing
0.62	GO:0097187	dentinogenesis
0.62	GO:2000098	negative regulation of smooth muscle cell-matrix adhesion
0.61	GO:0030193	regulation of blood coagulation
0.61	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.60	GO:0090399	replicative senescence
0.60	GO:0014912	negative regulation of smooth muscle cell migration

0.60	GO:0004867	serine-type endopeptidase inhibitor activity
0.57	GO:0002020	protease binding
0.54	GO:0005102	receptor binding
0.44	GO:0008201	heparin binding
0.36	GO:0035375	zymogen binding
0.34	GO:0008233	peptidase activity
0.33	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process

0.73	GO:0005615	extracellular space
0.55	GO:1903561	extracellular vesicle
0.55	GO:0031012	extracellular matrix
0.47	GO:0031091	platelet alpha granule
0.47	GO:0031232	extrinsic component of external side of plasma membrane
0.45	GO:0031594	neuromuscular junction
0.41	GO:0005829	cytosol
0.36	GO:0034774	secretory granule lumen
0.36	GO:0042583	chromaffin granule
0.34	GO:0048475	coated membrane

0.34

GO:0008233

sp|P05129|KPCG_HUMAN
Protein kinase C gamma type
Search

PRKCG

0.90	Protein kinase C gamma type

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0032425	positive regulation of mismatch repair
0.56	GO:0043278	response to morphine
0.55	GO:0032095	regulation of response to food
0.55	GO:0048265	response to pain
0.54	GO:0031397	negative regulation of protein ubiquitination
0.54	GO:1901799	negative regulation of proteasomal protein catabolic process
0.54	GO:0060384	innervation
0.53	GO:0042752	regulation of circadian rhythm

0.82	GO:0004697	protein kinase C activity
0.61	GO:0008270	zinc ion binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.51	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.47	GO:0035403	histone kinase activity (H3-T6 specific)
0.42	GO:0009931	calcium-dependent protein serine/threonine kinase activity
0.40	GO:0019899	enzyme binding

0.52	GO:0030425	dendrite
0.52	GO:0014069	postsynaptic density
0.50	GO:0097060	synaptic membrane
0.49	GO:0030054	cell junction
0.45	GO:0005622	intracellular
0.43	GO:0043227	membrane-bounded organelle
0.39	GO:0012505	endomembrane system
0.36	GO:0001750	photoreceptor outer segment
0.36	GO:0043230	extracellular organelle
0.35	GO:0035866	alphav-beta3 integrin-PKCalpha complex

0.82

EC:2.7.11.13

GO:0004697

sp|P05141|ADT2_HUMAN
ADP/ATP translocase 2
Search

SLC25A5

0.86	LOW QUALITY PROTEIN: ADP/ATP translocase 2

0.55	GO:0046902	regulation of mitochondrial membrane permeability
0.55	GO:0055085	transmembrane transport
0.52	GO:0010823	negative regulation of mitochondrion organization
0.50	GO:2001234	negative regulation of apoptotic signaling pathway
0.49	GO:0051051	negative regulation of transport
0.49	GO:0008284	positive regulation of cell proliferation
0.49	GO:0015866	ADP transport
0.48	GO:1990823	response to leukemia inhibitory factor
0.47	GO:0015867	ATP transport
0.46	GO:0071345	cellular response to cytokine stimulus

0.57	GO:0022857	transmembrane transporter activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003723	RNA binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.54	GO:0071817	MMXD complex
0.49	GO:0042645	mitochondrial nucleoid
0.48	GO:0043209	myelin sheath
0.38	GO:0045121	membrane raft
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0031301	integral component of organelle membrane
0.34	GO:0005634	nucleus

sp|P05154|IPSP_HUMAN
Plasma serine protease inhibitor
Search

0.82	Plasma serine protease inhibitor

0.57	GO:0010951	negative regulation of endopeptidase activity
0.50	GO:0007283	spermatogenesis
0.42	GO:0061107	seminal vesicle development
0.41	GO:0006508	proteolysis
0.38	GO:0070327	thyroid hormone transport
0.38	GO:0006953	acute-phase response
0.37	GO:0007338	single fertilization
0.36	GO:0006869	lipid transport
0.36	GO:0045026	plasma membrane fusion
0.35	GO:0007596	blood coagulation

0.58	GO:0004867	serine-type endopeptidase inhibitor activity
0.55	GO:0032190	acrosin binding
0.54	GO:0001972	retinoic acid binding
0.54	GO:0031210	phosphatidylcholine binding
0.53	GO:0002020	protease binding
0.41	GO:0008233	peptidase activity
0.37	GO:0008201	heparin binding
0.36	GO:0042802	identical protein binding
0.34	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.56	GO:0036025	protein C inhibitor-TMPRSS11E complex
0.56	GO:0097182	protein C inhibitor-coagulation factor Xa complex
0.56	GO:0097183	protein C inhibitor-coagulation factor XI complex
0.56	GO:0097181	protein C inhibitor-coagulation factor V complex
0.56	GO:0036030	protein C inhibitor-plasma kallikrein complex
0.56	GO:0036028	protein C inhibitor-thrombin complex
0.56	GO:0036029	protein C inhibitor-KLK3 complex
0.56	GO:0036024	protein C inhibitor-TMPRSS7 complex
0.56	GO:0036026	protein C inhibitor-PLAT complex

0.41

GO:0008233

sp|P05155|IC1_HUMAN
Plasma protease C1 inhibitor
Search

SERPING1

0.96	Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

0.86	GO:0045916	negative regulation of complement activation
0.84	GO:0030193	regulation of blood coagulation
0.77	GO:0001868	regulation of complement activation, lectin pathway
0.76	GO:0010951	negative regulation of endopeptidase activity
0.61	GO:0045824	negative regulation of innate immune response

0.79

GO:0004867

serine-type endopeptidase inhibitor activity

0.73

GO:0005615

extracellular space

sp|P05156|CFAI_HUMAN
Complement factor I
Search

CFI

0.97	Complement factor I

0.69	GO:0006898	receptor-mediated endocytosis
0.60	GO:0006508	proteolysis
0.41	GO:0006958	complement activation, classical pathway
0.40	GO:0045087	innate immune response
0.40	GO:0051604	protein maturation
0.38	GO:0030449	regulation of complement activation
0.36	GO:0071354	cellular response to interleukin-6
0.36	GO:0014909	smooth muscle cell migration
0.35	GO:0016042	lipid catabolic process
0.35	GO:0048008	platelet-derived growth factor receptor signaling pathway

0.78	GO:0005044	scavenger receptor activity
0.68	GO:0004252	serine-type endopeptidase activity
0.36	GO:0004623	phospholipase A2 activity
0.36	GO:0046872	metal ion binding
0.35	GO:0051219	phosphoprotein binding
0.34	GO:0004197	cysteine-type endopeptidase activity
0.34	GO:0005102	receptor binding

0.50	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.35	GO:0046658	anchored component of plasma membrane
0.35	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0030141	secretory granule
0.35	GO:0045177	apical part of cell
0.34	GO:0009986	cell surface
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.68

GO:0004252

sp|P05160|F13B_HUMAN
Coagulation factor XIII B chain
Search

F13B

0.73	Coagulation factor XIII B chain

0.30	GO:0050896	response to stimulus
0.30	GO:0050817	coagulation
0.30	GO:0050878	regulation of body fluid levels

0.30

GO:0005576

extracellular region

sp|P05161|ISG15_HUMAN
Ubiquitin-like protein ISG15
Search

ISG15

0.97	Ubiquitin protein ISG15 (Fragment)

0.86	GO:0032020	ISG15-protein conjugation
0.78	GO:0034340	response to type I interferon
0.77	GO:0042742	defense response to bacterium
0.77	GO:0051607	defense response to virus
0.76	GO:0045071	negative regulation of viral genome replication
0.75	GO:0032649	regulation of interferon-gamma production
0.75	GO:0031397	negative regulation of protein ubiquitination
0.72	GO:0030501	positive regulation of bone mineralization
0.67	GO:0045648	positive regulation of erythrocyte differentiation
0.57	GO:0019941	modification-dependent protein catabolic process

0.65	GO:0031386	protein tag
0.44	GO:0005515	protein binding
0.43	GO:0050840	extracellular matrix binding

0.60	GO:0005576	extracellular region
0.42	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane

sp|P05162|LEG2_HUMAN
Galectin-2
Search

LGALS2

0.66

Galectin

0.43	GO:0046598	positive regulation of viral entry into host cell
0.43	GO:0002317	plasma cell differentiation
0.42	GO:0031295	T cell costimulation
0.42	GO:0045445	myoblast differentiation
0.39	GO:0002040	sprouting angiogenesis
0.37	GO:0006915	apoptotic process
0.35	GO:0034120	positive regulation of erythrocyte aggregation
0.35	GO:0035900	response to isolation stress
0.35	GO:2001200	positive regulation of dendritic cell differentiation
0.34	GO:0048678	response to axon injury

0.70	GO:0030246	carbohydrate binding
0.41	GO:0016936	galactoside binding
0.35	GO:0005515	protein binding
0.34	GO:0050840	extracellular matrix binding
0.33	GO:0004871	signal transducer activity
0.32	GO:0003723	RNA binding

0.40	GO:0031012	extracellular matrix
0.39	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.34	GO:0009986	cell surface
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P05164|PERM_HUMAN
Myeloperoxidase
Search

MPO

0.94	Eosinophil peroxidase

0.72	GO:0006952	defense response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0002148	hypochlorous acid metabolic process
0.62	GO:1903409	reactive oxygen species biosynthetic process
0.57	GO:0034374	low-density lipoprotein particle remodeling
0.56	GO:0018969	thiocyanate metabolic process
0.56	GO:0001878	response to yeast
0.56	GO:0044130	negative regulation of growth of symbiont in host
0.56	GO:0045730	respiratory burst

0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.53	GO:0008201	heparin binding
0.36	GO:0030156	benzodiazepine receptor binding
0.35	GO:0003682	chromatin binding
0.34	GO:0046872	metal ion binding
0.34	GO:0004984	olfactory receptor activity

0.56	GO:0005766	primary lysosome
0.53	GO:0005615	extracellular space
0.53	GO:0030141	secretory granule
0.44	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.40	GO:1903561	extracellular vesicle
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0005775	vacuolar lumen
0.30	GO:0016021	integral component of membrane

0.72	EC:1.11.1.7	GO:0004601
0.72	KEGG:R03532	GO:0004601

sp|P05165|PCCA_HUMAN
Propionyl-CoA carboxylase alpha chain, mitochondrial
Search

PCCA

0.72	Propionyl-CoA carboxylase alpha subunit

0.38	GO:0009062	fatty acid catabolic process
0.37	GO:0019836	hemolysis by symbiont of host erythrocytes
0.36	GO:0046459	short-chain fatty acid metabolic process
0.36	GO:0006768	biotin metabolic process
0.35	GO:0009063	cellular amino acid catabolic process

0.76	GO:0004075	biotin carboxylase activity
0.62	GO:0004658	propionyl-CoA carboxylase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.51	GO:0019899	enzyme binding
0.36	GO:0033293	monocarboxylic acid binding
0.35	GO:0033218	amide binding

0.47	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol
0.34	GO:0005576	extracellular region

0.76

EC:6.3.4.14

GO:0004075

sp|P05166|PCCB_HUMAN
Propionyl-CoA carboxylase beta chain, mitochondrial
Search

PCCB

0.93	Propionyl coenzyme A carboxylase, beta polypeptide

0.44

GO:0009062

fatty acid catabolic process

0.62

GO:0016874

ligase activity

0.36

GO:0005739

mitochondrion

0.62

GO:0016874

sp|P05177|CP1A2_HUMAN
Cytochrome P450 1A2
Search

sp|P05181|CP2E1_HUMAN
Cytochrome P450 2E1
Search

CYP2E1

0.85	Cytochrome P450 family 2 subfamily e polypeptide 1

0.56	GO:0019373	epoxygenase P450 pathway
0.54	GO:0016098	monoterpenoid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0008202	steroid metabolic process
0.42	GO:0017144	drug metabolic process
0.41	GO:0002933	lipid hydroxylation
0.39	GO:0010193	response to ozone
0.39	GO:0070988	demethylation
0.39	GO:0006805	xenobiotic metabolic process
0.38	GO:0045471	response to ethanol

0.69	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.57	GO:0008392	arachidonic acid epoxygenase activity
0.55	GO:0008395	steroid hydroxylase activity
0.46	GO:0019899	enzyme binding
0.43	GO:0034875	caffeine oxidase activity
0.39	GO:0019825	oxygen binding
0.38	GO:0071614	linoleic acid epoxygenase activity
0.34	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

0.48	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0031984	organelle subcompartment
0.41	GO:0031090	organelle membrane
0.37	GO:0044431	Golgi apparatus part
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016712

sp|P05186|PPBT_HUMAN
Alkaline phosphatase, tissue-nonspecific isozyme
Search

ALPL

0.47	Alkaline phosphatase, tissue-nonspecific isozyme

0.68	GO:0016311	dephosphorylation
0.57	GO:0033280	response to vitamin D
0.57	GO:0001958	endochondral ossification
0.52	GO:0071407	cellular response to organic cyclic compound
0.51	GO:0003006	developmental process involved in reproduction
0.50	GO:0046677	response to antibiotic
0.44	GO:0009612	response to mechanical stimulus
0.42	GO:0071529	cementum mineralization
0.40	GO:0051384	response to glucocorticoid
0.39	GO:0032496	response to lipopolysaccharide

0.81	GO:0004035	alkaline phosphatase activity
0.44	GO:0016462	pyrophosphatase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.58	GO:0065010	extracellular membrane-bounded organelle
0.51	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005886	plasma membrane
0.41	GO:0031225	anchored component of membrane
0.38	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.81

GO:0004035

sp|P05187|PPB1_HUMAN
Alkaline phosphatase, placental type
Search

0.47	Intestinal-type alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.46	GO:0033280	response to vitamin D
0.46	GO:0001958	endochondral ossification
0.44	GO:0071310	cellular response to organic substance
0.43	GO:0003006	developmental process involved in reproduction
0.42	GO:0046677	response to antibiotic
0.40	GO:0071772	response to BMP
0.38	GO:0071495	cellular response to endogenous stimulus
0.38	GO:0006501	C-terminal protein lipidation
0.37	GO:0031214	biomineral tissue development

0.80	GO:0004035	alkaline phosphatase activity
0.45	GO:0002020	protease binding
0.39	GO:0000287	magnesium ion binding
0.38	GO:0008270	zinc ion binding
0.38	GO:0016462	pyrophosphatase activity
0.34	GO:0042803	protein homodimerization activity

0.47	GO:0065010	extracellular membrane-bounded organelle
0.44	GO:0031225	anchored component of membrane
0.43	GO:0005886	plasma membrane
0.43	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0009986	cell surface
0.38	GO:0098552	side of membrane
0.37	GO:0030016	myofibril
0.35	GO:0005903	brush border
0.34	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle

0.80

GO:0004035

sp|P05198|IF2A_HUMAN
Eukaryotic translation initiation factor 2 subunit 1
Search

EIF2S1

0.88	Eukaryotic translation initiation factor 2 subunit alpha

0.72	GO:0006413	translational initiation
0.61	GO:0032057	negative regulation of translational initiation in response to stress
0.57	GO:0034198	cellular response to amino acid starvation
0.56	GO:0034644	cellular response to UV
0.56	GO:1901216	positive regulation of neuron death
0.54	GO:0034976	response to endoplasmic reticulum stress
0.54	GO:0046777	protein autophosphorylation
0.40	GO:2000676	positive regulation of type B pancreatic cell apoptotic process
0.40	GO:0071287	cellular response to manganese ion
0.40	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity

0.73	GO:0003743	translation initiation factor activity
0.52	GO:0043022	ribosome binding
0.36	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0005850	eukaryotic translation initiation factor 2 complex
0.58	GO:0005851	eukaryotic translation initiation factor 2B complex
0.55	GO:0010494	cytoplasmic stress granule
0.48	GO:0043614	multi-eIF complex
0.46	GO:0033290	eukaryotic 48S preinitiation complex
0.45	GO:0005634	nucleus
0.41	GO:0044207	translation initiation ternary complex
0.40	GO:0005840	ribosome
0.40	GO:0097451	glial limiting end-foot
0.36	GO:0070062	extracellular exosome

sp|P05204|HMGN2_HUMAN
Non-histone chromosomal protein HMG-17
Search

HMGN2

0.94	High mobility group nucleosome-binding domain-containing protein 4

0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0031640	killing of cells of other organism
0.36	GO:0040034	regulation of development, heterochronic
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0006486	protein glycosylation

0.85	GO:0031492	nucleosomal DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.33	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.36	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm

0.33

EC:2.5 EC:2.5.1

GO:0016765

sp|P05230|FGF1_HUMAN
Fibroblast growth factor 1
Search

FGF1

0.54	Fibroblast growth factor 1

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.67	GO:0051781	positive regulation of cell division
0.67	GO:0001525	angiogenesis
0.66	GO:0060681	branch elongation involved in ureteric bud branching
0.65	GO:0045542	positive regulation of cholesterol biosynthetic process
0.64	GO:0045766	positive regulation of angiogenesis
0.61	GO:1901509	regulation of endothelial tube morphogenesis
0.61	GO:0030335	positive regulation of cell migration
0.61	GO:1903670	regulation of sprouting angiogenesis

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.67	GO:0008201	heparin binding
0.62	GO:0044548	S100 protein binding
0.60	GO:0005178	integrin binding
0.45	GO:0030544	Hsp70 protein binding
0.42	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.41	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.40	GO:0090722	receptor-receptor interaction
0.39	GO:0042056	chemoattractant activity

0.66	GO:0005576	extracellular region
0.60	GO:0005938	cell cortex
0.55	GO:0005829	cytosol
0.52	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part

0.42	EC:2.7.1.153	GO:0046934
0.42	KEGG:R04545	GO:0046934

sp|P05231|IL6_HUMAN
Interleukin-6
Search

IL6

0.94	Interleukin 6 (Interferon, beta 2)

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.59	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment
0.59	GO:0006954	inflammatory response
0.56	GO:0002252	immune effector process
0.56	GO:0001781	neutrophil apoptotic process
0.55	GO:0032966	negative regulation of collagen biosynthetic process
0.54	GO:0051024	positive regulation of immunoglobulin secretion
0.54	GO:0071354	cellular response to interleukin-6
0.53	GO:0002675	positive regulation of acute inflammatory response

0.86	GO:0005138	interleukin-6 receptor binding
0.80	GO:0005125	cytokine activity
0.57	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.55	GO:0005896	interleukin-6 receptor complex
0.37	GO:0005788	endoplasmic reticulum lumen

sp|P05305|EDN1_HUMAN
Endothelin-1
Search

EDN1

0.94	Preproendothelin

0.85	GO:0019229	regulation of vasoconstriction
0.70	GO:0042310	vasoconstriction
0.68	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity
0.67	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.67	GO:0014820	tonic smooth muscle contraction
0.65	GO:0014821	phasic smooth muscle contraction
0.65	GO:0010460	positive regulation of heart rate
0.65	GO:0042313	protein kinase C deactivation
0.64	GO:0046457	prostanoid biosynthetic process
0.64	GO:0030185	nitric oxide transport

0.69	GO:0031708	endothelin B receptor binding
0.65	GO:0031707	endothelin A receptor binding
0.59	GO:0005179	hormone activity
0.56	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.45	GO:0048237	rough endoplasmic reticulum lumen
0.44	GO:0033093	Weibel-Palade body
0.43	GO:0045178	basal part of cell
0.36	GO:0030133	transport vesicle
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:1.97.1

GO:0051353

sp|P05362|ICAM1_HUMAN
Intercellular adhesion molecule 1
Search

ICAM1

0.94	Intercellular adhesion molecule

0.76	GO:0098609	cell-cell adhesion
0.58	GO:0002457	T cell antigen processing and presentation
0.57	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.57	GO:0022614	membrane to membrane docking
0.56	GO:0002693	positive regulation of cellular extravasation
0.55	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.55	GO:0033627	cell adhesion mediated by integrin
0.55	GO:1900027	regulation of ruffle assembly
0.55	GO:0061028	establishment of endothelial barrier
0.55	GO:2000352	negative regulation of endothelial cell apoptotic process

0.62	GO:0005178	integrin binding
0.37	GO:0001618	virus receptor activity
0.35	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0003735	structural constituent of ribosome

0.54	GO:0001772	immunological synapse
0.52	GO:0070062	extracellular exosome
0.52	GO:0009897	external side of plasma membrane
0.51	GO:0098857	membrane microdomain
0.49	GO:0031012	extracellular matrix
0.46	GO:0005887	integral component of plasma membrane
0.37	GO:0005925	focal adhesion
0.33	GO:0005840	ribosome

sp|P05386|RLA1_HUMAN
60S acidic ribosomal protein P1
Search

RPLP1

0.73	Ribosomal protein lateral stalk subunit P1

0.69	GO:0006414	translational elongation
0.50	GO:0032147	activation of protein kinase activity
0.49	GO:0002181	cytoplasmic translation
0.44	GO:0030218	erythrocyte differentiation
0.36	GO:0006417	regulation of translation
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0034250	positive regulation of cellular amide metabolic process
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.51	GO:0030295	protein kinase activator activity
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0005515	protein binding
0.32	GO:0003777	microtubule motor activity
0.32	GO:0016740	transferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0008144	drug binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|P05387|RLA2_HUMAN
60S acidic ribosomal protein P2
Search

RPLP2

0.79	Renal carcinoma antigen NY-REN-44

0.69	GO:0006414	translational elongation
0.46	GO:0002181	cytoplasmic translation
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0043009	chordate embryonic development
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0042254	ribosome biogenesis
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0045727	positive regulation of translation
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0030218	erythrocyte differentiation

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0005515	protein binding
0.33	GO:0005506	iron ion binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P05388|RLA0_HUMAN
60S acidic ribosomal protein P0
Search

RPLP0

0.67	60S acidic ribosomal protein P0

0.66	GO:0042254	ribosome biogenesis
0.48	GO:0071353	cellular response to interleukin-4
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0010269	response to selenium ion
0.35	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.35	GO:0007595	lactation
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0043009	chordate embryonic development

0.43	GO:0003735	structural constituent of ribosome
0.34	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.60	GO:0005840	ribosome
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0044445	cytosolic part
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0030425	dendrite
0.43	GO:0005634	nucleus
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P05408|7B2_HUMAN
Neuroendocrine protein 7B2
Search

SCG5

0.90	Secretogranin V

0.80	GO:0007218	neuropeptide signaling pathway
0.58	GO:0016486	peptide hormone processing
0.56	GO:0046883	regulation of hormone secretion
0.51	GO:0043086	negative regulation of catalytic activity
0.50	GO:0006886	intracellular protein transport

0.52	GO:0004857	enzyme inhibitor activity
0.51	GO:0051082	unfolded protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0030141	secretory granule
0.37	GO:0005576	extracellular region
0.35	GO:0031514	motile cilium
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P05412|JUN_HUMAN
Transcription factor AP-1
Search

JUN

0.95	AP-1 transcription factor c-Jun subunit

0.57	GO:0035026	leading edge cell differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0001774	microglial cell activation
0.56	GO:0061029	eyelid development in camera-type eye
0.56	GO:0031953	negative regulation of protein autophosphorylation
0.56	GO:0046686	response to cadmium ion
0.56	GO:1903131	mononuclear cell differentiation
0.55	GO:0035994	response to muscle stretch

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.55	GO:0070412	R-SMAD binding
0.53	GO:0001102	RNA polymerase II activating transcription factor binding
0.53	GO:0003713	transcription coactivator activity
0.53	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0003682	chromatin binding
0.49	GO:0005096	GTPase activator activity
0.49	GO:0042803	protein homodimerization activity

0.56	GO:0035976	transcription factor AP-1 complex
0.53	GO:0005719	nuclear euchromatin
0.52	GO:0017053	transcriptional repressor complex
0.47	GO:0005654	nucleoplasm
0.37	GO:0005829	cytosol
0.33	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P05413|FABPH_HUMAN
Fatty acid-binding protein, heart
Search

FABP3

0.82	Fatty acid-binding protein heart

0.52	GO:0042632	cholesterol homeostasis
0.52	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.52	GO:0055091	phospholipid homeostasis
0.52	GO:0044539	long-chain fatty acid import
0.51	GO:0046320	regulation of fatty acid oxidation
0.47	GO:0050727	regulation of inflammatory response
0.41	GO:0050872	white fat cell differentiation
0.41	GO:0071285	cellular response to lithium ion
0.40	GO:0032501	multicellular organismal process
0.40	GO:0010033	response to organic substance

0.72	GO:0008289	lipid binding
0.53	GO:0033293	monocarboxylic acid binding
0.47	GO:0008092	cytoskeletal protein binding
0.39	GO:0005324	long-chain fatty acid transporter activity
0.35	GO:0043178	alcohol binding
0.34	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.32	GO:0097159	organic cyclic compound binding

0.48	GO:0005615	extracellular space
0.41	GO:0043209	myelin sheath
0.39	GO:0016528	sarcoplasm
0.37	GO:0005829	cytosol
0.37	GO:1903561	extracellular vesicle
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0043233	organelle lumen
0.34	GO:0043025	neuronal cell body
0.34	GO:0005811	lipid droplet
0.33	GO:0005911	cell-cell junction

sp|P05423|RPC4_HUMAN
DNA-directed RNA polymerase III subunit RPC4
Search

POLR3D

0.93	RNA polymerase III subunit D

0.81	GO:0006383	transcription by RNA polymerase III
0.64	GO:0032728	positive regulation of interferon-beta production
0.59	GO:0045089	positive regulation of innate immune response
0.39	GO:0045087	innate immune response
0.39	GO:0051607	defense response to virus
0.37	GO:0031047	gene silencing by RNA
0.31	GO:1903506	regulation of nucleic acid-templated transcription
0.31	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.56	GO:0003682	chromatin binding
0.55	GO:0003677	DNA binding
0.31	GO:0046872	metal ion binding

0.81	GO:0005666	DNA-directed RNA polymerase III complex
0.58	GO:0016607	nuclear speck
0.56	GO:0000790	nuclear chromatin
0.52	GO:0005829	cytosol

0.70

EC:2.7.7.6

GO:0003899

sp|P05451|REG1A_HUMAN
Lithostathine-1-alpha
Search

0.97	Pancreatic beta cell growth factor

0.52	GO:0044278	cell wall disruption in other organism
0.52	GO:0010469	regulation of receptor activity
0.52	GO:0007155	cell adhesion
0.52	GO:0048731	system development
0.50	GO:0008284	positive regulation of cell proliferation
0.50	GO:0019730	antimicrobial humoral response
0.50	GO:0098743	cell aggregation
0.50	GO:1990864	response to growth hormone-releasing hormone
0.50	GO:1904697	regulation of acinar cell proliferation
0.50	GO:1990867	response to gastrin

0.62	GO:0005539	glycosaminoglycan binding
0.57	GO:0030246	carbohydrate binding
0.54	GO:0008083	growth factor activity
0.51	GO:0043177	organic acid binding
0.48	GO:0042802	identical protein binding
0.46	GO:0001871	pattern binding
0.45	GO:0019903	protein phosphatase binding
0.44	GO:0005509	calcium ion binding
0.44	GO:0043168	anion binding
0.43	GO:1901681	sulfur compound binding

0.53	GO:0005615	extracellular space
0.48	GO:0005604	basement membrane
0.47	GO:0031982	vesicle
0.47	GO:0032809	neuronal cell body membrane
0.46	GO:0032590	dendrite membrane
0.46	GO:0045178	basal part of cell
0.45	GO:0043230	extracellular organelle
0.45	GO:0030426	growth cone
0.44	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0012505	endomembrane system

0.35	EC:2.3.3.10	GO:0004421
0.35	KEGG:R01978	GO:0004421

sp|P05452|TETN_HUMAN
Tetranectin
Search

CLEC3B

0.97	Tetranectin

0.70	GO:0030282	bone mineralization
0.66	GO:0071560	cellular response to transforming growth factor beta stimulus
0.57	GO:0010756	positive regulation of plasminogen activation
0.38	GO:0001501	skeletal system development
0.38	GO:0002576	platelet degranulation

0.76	GO:0036143	kringle domain binding
0.66	GO:0008201	heparin binding
0.59	GO:0030246	carbohydrate binding
0.58	GO:0005509	calcium ion binding

0.73	GO:0001652	granular component
0.60	GO:0005615	extracellular space
0.43	GO:0005737	cytoplasm
0.39	GO:0031012	extracellular matrix
0.39	GO:1903561	extracellular vesicle
0.38	GO:0031983	vesicle lumen
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|P05455|LA_HUMAN
Lupus La protein
Search

SSB

0.90	Sjogren syndrome antigen B

0.77	GO:0071045	nuclear histone mRNA catabolic process
0.74	GO:1903608	protein localization to cytoplasmic stress granule
0.73	GO:0075522	IRES-dependent viral translational initiation
0.72	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.71	GO:0051031	tRNA transport
0.70	GO:0097064	ncRNA export from nucleus
0.65	GO:0001682	tRNA 5'-leader removal
0.64	GO:0042780	tRNA 3'-end processing

0.74	GO:1990825	sequence-specific mRNA binding
0.70	GO:0008266	poly(U) RNA binding
0.58	GO:0000049	tRNA binding

0.61	GO:0005634	nucleus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0005737	cytoplasm

sp|P05496|AT5G1_HUMAN
ATP synthase F(0) complex subunit C1, mitochondrial
Search

0.86	ATP synthase lipid-binding protein, mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0045471	response to ethanol
0.36	GO:0042407	cristae formation
0.36	GO:0006839	mitochondrial transport
0.35	GO:0046907	intracellular transport
0.34	GO:0007568	aging
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.44	GO:0019829	cation-transporting ATPase activity
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.47	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004450

sp|P05538|DQB2_HUMAN
HLA class II histocompatibility antigen, DQ beta 2 chain
Search

HLA-DQB1

0.74	HLA class II histocompatibility antigen, DQ beta 2 chain

0.83	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.74	GO:0006955	immune response
0.48	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.48	GO:0031295	T cell costimulation
0.48	GO:0050852	T cell receptor signaling pathway
0.45	GO:0019221	cytokine-mediated signaling pathway
0.43	GO:0006952	defense response
0.42	GO:0002377	immunoglobulin production
0.41	GO:0002449	lymphocyte mediated immunity

0.51	GO:0032395	MHC class II receptor activity
0.43	GO:0042605	peptide antigen binding
0.35	GO:0046872	metal ion binding

0.76	GO:0042613	MHC class II protein complex
0.48	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.48	GO:0032588	trans-Golgi network membrane
0.47	GO:0030669	clathrin-coated endocytic vesicle membrane
0.46	GO:0005765	lysosomal membrane
0.46	GO:0012507	ER to Golgi transport vesicle membrane
0.45	GO:0010008	endosome membrane

sp|P05543|THBG_HUMAN
Thyroxine-binding globulin
Search

SERPINA7

0.94	LOW QUALITY PROTEIN: thyroxine-binding globulin

0.56	GO:0070327	thyroid hormone transport
0.51	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0033189	response to vitamin A
0.36	GO:0051412	response to corticosterone
0.35	GO:0034695	response to prostaglandin E
0.35	GO:0043434	response to peptide hormone
0.35	GO:0007568	aging
0.34	GO:0009791	post-embryonic development
0.34	GO:0002576	platelet degranulation
0.34	GO:0008211	glucocorticoid metabolic process

0.53	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0015349	thyroid hormone transmembrane transporter activity
0.35	GO:0042562	hormone binding
0.34	GO:0002020	protease binding
0.33	GO:0005496	steroid binding
0.33	GO:0042802	identical protein binding
0.32	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.34	GO:0031089	platelet dense granule lumen
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.32

GO:0008233

sp|P05546|HEP2_HUMAN
Heparin cofactor 2
Search

SERPIND1

0.97	Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1

0.65	GO:0007596	blood coagulation
0.63	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0043687	post-translational protein modification
0.34	GO:0006935	chemotaxis
0.34	GO:0006508	proteolysis
0.32	GO:0043066	negative regulation of apoptotic process

0.65	GO:0004867	serine-type endopeptidase inhibitor activity
0.40	GO:0008201	heparin binding
0.34	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

0.34

GO:0008233

sp|P05549|AP2A_HUMAN
Transcription factor AP-2-alpha
Search

TFAP2A

0.57	Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha)

0.59	GO:0042472	inner ear morphogenesis
0.57	GO:0070172	positive regulation of tooth mineralization
0.56	GO:0010944	negative regulation of transcription by competitive promoter binding
0.56	GO:0043010	camera-type eye development
0.55	GO:0071281	cellular response to iron ion
0.55	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.54	GO:0030501	positive regulation of bone mineralization
0.54	GO:0048646	anatomical structure formation involved in morphogenesis
0.54	GO:0060021	palate development
0.53	GO:0043525	positive regulation of neuron apoptotic process

0.60	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003713	transcription coactivator activity
0.45	GO:0046983	protein dimerization activity
0.38	GO:0003682	chromatin binding
0.37	GO:0001106	RNA polymerase II transcription corepressor activity
0.37	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.34	GO:0042802	identical protein binding

0.60	GO:0005634	nucleus
0.50	GO:0005813	centrosome
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.45	GO:0043233	organelle lumen
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|P05556|ITB1_HUMAN
Integrin beta-1
Search

ITGB1

0.68	Integrin beta

0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.51	GO:0010710	regulation of collagen catabolic process
0.51	GO:0021943	formation of radial glial scaffolds
0.51	GO:0033631	cell-cell adhesion mediated by integrin
0.50	GO:0002042	cell migration involved in sprouting angiogenesis
0.50	GO:2000811	negative regulation of anoikis
0.50	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.50	GO:0050901	leukocyte tethering or rolling
0.50	GO:0034113	heterotypic cell-cell adhesion

0.65	GO:0004872	receptor activity
0.54	GO:0001968	fibronectin binding
0.51	GO:0019960	C-X3-C chemokine binding
0.51	GO:0098639	collagen binding involved in cell-matrix adhesion
0.49	GO:0043236	laminin binding
0.49	GO:0046982	protein heterodimerization activity
0.49	GO:0005178	integrin binding
0.48	GO:0002020	protease binding
0.47	GO:0045296	cadherin binding
0.45	GO:0003779	actin binding

0.81	GO:0008305	integrin complex
0.52	GO:0071438	invadopodium membrane
0.51	GO:0035748	myelin sheath abaxonal region
0.50	GO:0032587	ruffle membrane
0.49	GO:0014704	intercalated disc
0.49	GO:0031594	neuromuscular junction
0.49	GO:0042383	sarcolemma
0.49	GO:0043197	dendritic spine
0.48	GO:0030175	filopodium
0.48	GO:0005925	focal adhesion

sp|P05771|KPCB_HUMAN
Protein kinase C beta type
Search

PRKCB

0.92	Protein kinase C beta type

0.63	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.57	GO:0018210	peptidyl-threonine modification
0.56	GO:0045766	positive regulation of angiogenesis
0.55	GO:0050853	B cell receptor signaling pathway
0.55	GO:0050861	positive regulation of B cell receptor signaling pathway
0.55	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.54	GO:0010829	negative regulation of glucose transport
0.53	GO:0042113	B cell activation
0.53	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.82	GO:0004697	protein kinase C activity
0.62	GO:0035403	histone kinase activity (H3-T6 specific)
0.62	GO:0008270	zinc ion binding
0.56	GO:0050681	androgen receptor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.54	GO:0005080	protein kinase C binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding

0.49	GO:0005829	cytosol
0.46	GO:0005654	nucleoplasm
0.43	GO:0005886	plasma membrane
0.40	GO:0005783	endoplasmic reticulum
0.38	GO:0070062	extracellular exosome
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0097733	photoreceptor cell cilium
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0005903	brush border

0.82

EC:2.7.11.13

GO:0004697

sp|P05783|K1C18_HUMAN
Keratin, type I cytoskeletal 18
Search

KRT18

0.84	Putative nuclear envelope protein lamin intermediate filament superfamily

0.51	GO:0043000	Golgi to plasma membrane CFTR protein transport
0.47	GO:0045104	intermediate filament cytoskeleton organization
0.47	GO:0097284	hepatocyte apoptotic process
0.46	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.46	GO:0097191	extrinsic apoptotic signaling pathway
0.45	GO:0043066	negative regulation of apoptotic process
0.45	GO:0098609	cell-cell adhesion
0.36	GO:0070268	cornification
0.34	GO:0009653	anatomical structure morphogenesis
0.34	GO:0097010	eukaryotic translation initiation factor 4F complex assembly

0.62	GO:0005198	structural molecule activity
0.48	GO:0098641	cadherin binding involved in cell-cell adhesion
0.48	GO:0097110	scaffold protein binding
0.34	GO:0003723	RNA binding

0.79	GO:0005882	intermediate filament
0.48	GO:0034451	centriolar satellite
0.47	GO:0005913	cell-cell adherens junction
0.43	GO:0005829	cytosol
0.37	GO:0071944	cell periphery
0.37	GO:0016363	nuclear matrix
0.37	GO:0005730	nucleolus
0.37	GO:0070062	extracellular exosome
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0036338	viral membrane

sp|P05787|K2C8_HUMAN
Keratin, type II cytoskeletal 8
Search

KRT8

0.85	Keratin, type II cytoskeletal 8

0.45	GO:0097284	hepatocyte apoptotic process
0.44	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.43	GO:0097191	extrinsic apoptotic signaling pathway
0.43	GO:0060706	cell differentiation involved in embryonic placenta development
0.40	GO:0043207	response to external biotic stimulus
0.40	GO:0051599	response to hydrostatic pressure
0.38	GO:0045214	sarcomere organization
0.38	GO:0051704	multi-organism process
0.36	GO:0070268	cornification
0.34	GO:0000904	cell morphogenesis involved in differentiation

0.62	GO:0005198	structural molecule activity
0.45	GO:0097110	scaffold protein binding
0.37	GO:0032403	protein complex binding
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.82	GO:0045095	keratin filament
0.44	GO:0016327	apicolateral plasma membrane
0.43	GO:0042383	sarcolemma
0.43	GO:0030018	Z disc
0.41	GO:0016363	nuclear matrix
0.41	GO:0005911	cell-cell junction
0.39	GO:0043034	costamere
0.38	GO:0005654	nucleoplasm
0.38	GO:0016010	dystrophin-associated glycoprotein complex
0.36	GO:0070062	extracellular exosome

sp|P05813|CRBA1_HUMAN
Beta-crystallin A3
Search

CRYBA1

0.97	Beta crystallin A3 chain transcript CN (Fragment)

0.66	GO:0007601	visual perception
0.45	GO:2000210	positive regulation of anoikis
0.44	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.43	GO:0043010	camera-type eye development
0.43	GO:0051898	negative regulation of protein kinase B signaling
0.43	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.42	GO:0032007	negative regulation of TOR signaling
0.42	GO:0001818	negative regulation of cytokine production

0.69	GO:0005212	structural constituent of eye lens
0.38	GO:0042803	protein homodimerization activity

0.37	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|P05814|CASB_HUMAN
Beta-casein
Search

CSN2

0.97	Beta-casein

0.58	GO:0007595	lactation
0.56	GO:2000117	negative regulation of cysteine-type endopeptidase activity
0.50	GO:1903488	negative regulation of lactation
0.44	GO:0006816	calcium ion transport
0.37	GO:1903720	negative regulation of I-kappaB phosphorylation
0.36	GO:1903494	response to dehydroepiandrosterone
0.36	GO:1903496	response to 11-deoxycorticosterone
0.36	GO:0009408	response to heat
0.35	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.35	GO:0032570	response to progesterone

0.55	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.42	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.36	GO:0019870	potassium channel inhibitor activity
0.35	GO:0008191	metalloendopeptidase inhibitor activity
0.34	GO:0016209	antioxidant activity

0.66	GO:0005576	extracellular region
0.35	GO:0005796	Golgi lumen

sp|P05937|CALB1_HUMAN
Calbindin
Search

CALB1

0.96	Cerebellar calbindin

0.74	GO:0055074	calcium ion homeostasis
0.62	GO:0072027	connecting tubule development
0.61	GO:0072221	metanephric distal convoluted tubule development
0.61	GO:0035502	metanephric part of ureteric bud development
0.60	GO:0072205	metanephric collecting duct development
0.60	GO:0007614	short-term memory
0.59	GO:1900271	regulation of long-term synaptic potentiation
0.58	GO:0007616	long-term memory
0.58	GO:0010842	retina layer formation
0.55	GO:0007626	locomotory behavior

0.70	GO:0005509	calcium ion binding
0.47	GO:0008270	zinc ion binding
0.43	GO:0005499	vitamin D binding
0.33	GO:0005515	protein binding

0.56	GO:0043005	neuron projection
0.55	GO:0043025	neuronal cell body
0.54	GO:0045202	synapse
0.53	GO:0120038	plasma membrane bounded cell projection part
0.52	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.44	GO:0005921	gap junction
0.36	GO:0070062	extracellular exosome
0.34	GO:0098590	plasma membrane region
0.34	GO:0012506	vesicle membrane

sp|P05976|MYL1_HUMAN
Myosin light chain 1/3, skeletal muscle isoform
Search

MYL1

0.93	Myosin essential light chain fast

0.58	GO:0006936	muscle contraction
0.49	GO:0060047	heart contraction
0.47	GO:0002026	regulation of the force of heart contraction
0.47	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.46	GO:0006942	regulation of striated muscle contraction
0.37	GO:0033275	actin-myosin filament sliding
0.37	GO:0007519	skeletal muscle tissue development
0.35	GO:0043520	regulation of myosin II filament assembly
0.35	GO:0032781	positive regulation of ATPase activity
0.32	GO:0006508	proteolysis

0.70	GO:0005509	calcium ion binding
0.46	GO:0003785	actin monomer binding
0.36	GO:0008307	structural constituent of muscle
0.35	GO:0003774	motor activity
0.35	GO:0032038	myosin II heavy chain binding
0.33	GO:0051015	actin filament binding
0.33	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.57	GO:0030016	myofibril
0.46	GO:0044449	contractile fiber part
0.42	GO:0016459	myosin complex
0.34	GO:0005829	cytosol

0.33

EC:1.3.99.3

GO:0003995

sp|P05981|HEPS_HUMAN
Serine protease hepsin
Search

HPN

0.94	Truncated hepsin serine protease

0.61	GO:2000347	positive regulation of hepatocyte proliferation
0.61	GO:0034769	basement membrane disassembly
0.61	GO:0010756	positive regulation of plasminogen activation
0.61	GO:0006508	proteolysis
0.60	GO:0043923	positive regulation by host of viral transcription
0.59	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.57	GO:0050680	negative regulation of epithelial cell proliferation
0.57	GO:0030307	positive regulation of cell growth
0.54	GO:0043066	negative regulation of apoptotic process
0.53	GO:0097195	pilomotor reflex

0.69	GO:0004252	serine-type endopeptidase activity
0.67	GO:0070008	serine-type exopeptidase activity
0.53	GO:0005044	scavenger receptor activity
0.49	GO:0015269	calcium-activated potassium channel activity
0.36	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0005242	inward rectifier potassium channel activity
0.33	GO:0017080	sodium channel regulator activity
0.31	GO:0016491	oxidoreductase activity

0.55	GO:0031965	nuclear membrane
0.53	GO:0009986	cell surface
0.51	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005887	integral component of plasma membrane
0.48	GO:0043025	neuronal cell body
0.46	GO:0005911	cell-cell junction
0.39	GO:0016324	apical plasma membrane
0.38	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.33	GO:0046658	anchored component of plasma membrane

0.69

GO:0004252

sp|P05997|CO5A2_HUMAN
Collagen alpha-2(V) chain
Search

COL5A2

0.82	Collagen type II alpha 1 chain

0.67	GO:1903225	negative regulation of endodermal cell differentiation
0.64	GO:0030199	collagen fibril organization
0.61	GO:0071230	cellular response to amino acid stimulus
0.61	GO:0043588	skin development
0.60	GO:0048592	eye morphogenesis
0.59	GO:0001501	skeletal system development
0.41	GO:0001503	ossification
0.37	GO:0030574	collagen catabolic process
0.37	GO:0033334	fin morphogenesis
0.36	GO:0007605	sensory perception of sound

0.81	GO:0005201	extracellular matrix structural constituent
0.62	GO:0046332	SMAD binding
0.37	GO:0048407	platelet-derived growth factor binding
0.37	GO:0042289	MHC class II protein binding
0.36	GO:0046872	metal ion binding

0.75	GO:0005581	collagen trimer
0.65	GO:0098643	banded collagen fibril
0.55	GO:0005615	extracellular space
0.36	GO:0005788	endoplasmic reticulum lumen

sp|P06028|GLPB_HUMAN
Glycophorin-B
Search

GYPB

0.91	Glycophorin B Miltenberger subtype III

0.39	GO:0050900	leukocyte migration
0.36	GO:0047484	regulation of response to osmotic stress
0.36	GO:0007016	cytoskeletal anchoring at plasma membrane
0.34	GO:0030260	entry into host cell
0.34	GO:0019058	viral life cycle

0.38	GO:0005515	protein binding
0.36	GO:0104005	hijacked molecular function

0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0009897	external side of plasma membrane
0.35	GO:0070062	extracellular exosome

sp|P06126|CD1A_HUMAN
T-cell surface glycoprotein CD1a
Search

0.91	T-cell surface glycoprotein CD1e, membrane-associated

0.58	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib
0.53	GO:0019884	antigen processing and presentation of exogenous antigen
0.44	GO:0019883	antigen processing and presentation of endogenous antigen
0.44	GO:0042102	positive regulation of T cell proliferation
0.43	GO:0006955	immune response
0.38	GO:0042110	T cell activation
0.36	GO:0002252	immune effector process
0.36	GO:0050776	regulation of immune response
0.36	GO:0006952	defense response
0.34	GO:0034113	heterotypic cell-cell adhesion

0.59	GO:0030884	exogenous lipid antigen binding
0.56	GO:0030883	endogenous lipid antigen binding
0.55	GO:0071723	lipopeptide binding
0.55	GO:0030881	beta-2-microglobulin binding
0.42	GO:0050839	cell adhesion molecule binding
0.42	GO:0042393	histone binding
0.38	GO:0051861	glycolipid binding

0.43	GO:0012505	endomembrane system
0.42	GO:0005765	lysosomal membrane
0.42	GO:0044433	cytoplasmic vesicle part
0.42	GO:0009986	cell surface
0.41	GO:0005886	plasma membrane
0.36	GO:0045121	membrane raft
0.35	GO:0031984	organelle subcompartment
0.34	GO:0043202	lysosomal lumen
0.30	GO:0016021	integral component of membrane

sp|P06127|CD5_HUMAN
T-cell surface glycoprotein CD5
Search

CD5

0.97	T-cell surface glycoprotein CD5

0.72	GO:0006898	receptor-mediated endocytosis
0.64	GO:0031295	T cell costimulation
0.60	GO:0097190	apoptotic signaling pathway
0.37	GO:0008037	cell recognition
0.37	GO:0008283	cell proliferation
0.35	GO:0009966	regulation of signal transduction

0.81	GO:0005044	scavenger receptor activity
0.37	GO:0005515	protein binding
0.36	GO:0099600	transmembrane receptor activity
0.35	GO:0038023	signaling receptor activity

0.60	GO:0009897	external side of plasma membrane
0.37	GO:0044214	spanning component of plasma membrane

sp|P06132|DCUP_HUMAN
Uroporphyrinogen decarboxylase
Search

UROD

0.49	Uroporphyrinogen decarboxylase

0.71	GO:0006782	protoporphyrinogen IX biosynthetic process
0.36	GO:0046502	uroporphyrinogen III metabolic process
0.35	GO:0051597	response to methylmercury
0.35	GO:0060992	response to fungicide
0.35	GO:0071243	cellular response to arsenic-containing substance
0.35	GO:0014075	response to amine
0.35	GO:0032355	response to estradiol
0.35	GO:0010039	response to iron ion
0.35	GO:0045471	response to ethanol
0.35	GO:0001889	liver development

0.78	GO:0004853	uroporphyrinogen decarboxylase activity
0.34	GO:0008198	ferrous iron binding
0.33	GO:0005515	protein binding

0.50	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm

0.78

EC:4.1.1.37

GO:0004853

sp|P06133|UD2B4_HUMAN
UDP-glucuronosyltransferase 2B4
Search

0.54	UDP-glucuronosyltransferase

0.50	GO:0052695	cellular glucuronidation
0.40	GO:0008202	steroid metabolic process
0.38	GO:0034754	cellular hormone metabolic process
0.37	GO:0006805	xenobiotic metabolic process
0.36	GO:0007608	sensory perception of smell
0.34	GO:0016042	lipid catabolic process
0.34	GO:0072329	monocarboxylic acid catabolic process
0.33	GO:1901615	organic hydroxy compound metabolic process
0.33	GO:0009593	detection of chemical stimulus
0.33	GO:0009636	response to toxic substance

0.80	GO:0015020	glucuronosyltransferase activity
0.39	GO:0001972	retinoic acid binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0005635	nuclear envelope
0.34	GO:0098805	whole membrane
0.33	GO:0019867	outer membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:2.4.1.17

GO:0015020

sp|P06213|INSR_HUMAN
Insulin receptor
Search

INSR

0.67	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.76	GO:0046777	protein autophosphorylation
0.54	GO:0060267	positive regulation of respiratory burst
0.54	GO:0045821	positive regulation of glycolytic process
0.53	GO:0045725	positive regulation of glycogen biosynthetic process
0.53	GO:0051290	protein heterotetramerization
0.53	GO:0032148	activation of protein kinase B activity
0.52	GO:0046326	positive regulation of glucose import
0.52	GO:0045429	positive regulation of nitric oxide biosynthetic process

0.84	GO:0043560	insulin receptor substrate binding
0.82	GO:0043548	phosphatidylinositol 3-kinase binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0051425	PTB domain binding
0.55	GO:0043559	insulin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0031995	insulin-like growth factor II binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005899	insulin receptor complex
0.54	GO:0106003	amyloid-beta complex
0.51	GO:0005901	caveola
0.48	GO:0005635	nuclear envelope
0.45	GO:0031981	nuclear lumen
0.38	GO:0032809	neuronal cell body membrane
0.38	GO:0032590	dendrite membrane
0.37	GO:0009897	external side of plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0005768	endosome

0.80

GO:0004714

sp|P06239|LCK_HUMAN
Tyrosine-protein kinase Lck
Search

LCK

0.62	Proto-oncogene tyrosine-protein kinase LCK

0.77	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.77	GO:0006882	cellular zinc ion homeostasis
0.76	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.75	GO:0030217	T cell differentiation
0.69	GO:0050870	positive regulation of T cell activation
0.67	GO:0050853	B cell receptor signaling pathway
0.64	GO:0006470	protein dephosphorylation
0.63	GO:0046777	protein autophosphorylation
0.63	GO:0042493	response to drug

0.78	GO:0042169	SH2 domain binding
0.77	GO:0004713	protein tyrosine kinase activity
0.73	GO:0042610	CD8 receptor binding
0.71	GO:0042608	T cell receptor binding
0.69	GO:0004722	protein serine/threonine phosphatase activity
0.68	GO:0043548	phosphatidylinositol 3-kinase binding
0.67	GO:0001784	phosphotyrosine residue binding
0.67	GO:0051117	ATPase binding
0.65	GO:0019903	protein phosphatase binding
0.65	GO:0008022	protein C-terminus binding

0.78	GO:0000242	pericentriolar material
0.72	GO:0098857	membrane microdomain
0.67	GO:0001772	immunological synapse
0.62	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.52	GO:0070062	extracellular exosome
0.50	GO:0005911	cell-cell junction
0.47	GO:0005829	cytosol
0.46	GO:0030139	endocytic vesicle

0.77	EC:2.7.10	GO:0004713
0.49	KEGG:R04545	GO:0046934

sp|P06241|FYN_HUMAN
Tyrosine-protein kinase Fyn
Search

FYN

0.65	Tyrosine-protein kinase Fyn

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.72	GO:0050852	T cell receptor signaling pathway
0.69	GO:0042110	T cell activation
0.69	GO:1902951	negative regulation of dendritic spine maintenance
0.68	GO:0046777	protein autophosphorylation
0.67	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.67	GO:1905430	cellular response to glycine
0.67	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.67	GO:0001764	neuron migration
0.66	GO:0090314	positive regulation of protein targeting to membrane

0.75	GO:0004713	protein tyrosine kinase activity
0.65	GO:0042610	CD8 receptor binding
0.65	GO:0097718	disordered domain specific binding
0.64	GO:0046875	ephrin receptor binding
0.64	GO:0031802	type 5 metabotropic glutamate receptor binding
0.64	GO:0044325	ion channel binding
0.63	GO:0042608	T cell receptor binding
0.62	GO:0070851	growth factor receptor binding
0.62	GO:0051428	peptide hormone receptor binding
0.61	GO:0043548	phosphatidylinositol 3-kinase binding

0.67	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.64	GO:0098857	membrane microdomain
0.63	GO:0014069	postsynaptic density
0.62	GO:0005884	actin filament
0.61	GO:0030425	dendrite
0.58	GO:0005768	endosome
0.57	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.46	GO:0005739	mitochondrion

0.75	EC:2.7.10	GO:0004713
0.49	KEGG:R04545	GO:0046934

sp|P06276|CHLE_HUMAN
Cholinesterase
Search

BCHE

0.50	Cholinesterase

0.61	GO:0051593	response to folic acid
0.59	GO:0014016	neuroblast differentiation
0.58	GO:0050805	negative regulation of synaptic transmission
0.58	GO:0043279	response to alkaloid
0.58	GO:0051384	response to glucocorticoid
0.57	GO:0007612	learning
0.57	GO:0050783	cocaine metabolic process
0.55	GO:0019695	choline metabolic process
0.54	GO:0008285	negative regulation of cell proliferation

0.85	GO:0003990	acetylcholinesterase activity
0.57	GO:0033265	choline binding
0.57	GO:0042802	identical protein binding
0.51	GO:0001540	amyloid-beta binding
0.45	GO:0019899	enzyme binding

0.66	GO:0005641	nuclear envelope lumen
0.64	GO:0005576	extracellular region
0.57	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.1.1.7

GO:0003990

sp|P06280|AGAL_HUMAN
Alpha-galactosidase A
Search

GLA

0.94	Alpha-galactosidase A

0.60	GO:0005975	carbohydrate metabolic process
0.51	GO:0016139	glycoside catabolic process
0.49	GO:0046477	glycosylceramide catabolic process
0.39	GO:0051001	negative regulation of nitric-oxide synthase activity
0.39	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.37	GO:0030282	bone mineralization
0.36	GO:0043312	neutrophil degranulation
0.34	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0015031	protein transport
0.33	GO:0035556	intracellular signal transduction

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0005102	receptor binding
0.41	GO:0016936	galactoside binding
0.34	GO:0004713	protein tyrosine kinase activity
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.52	GO:0005764	lysosome
0.48	GO:0005794	Golgi apparatus
0.46	GO:0005576	extracellular region
0.36	GO:0034774	secretory granule lumen
0.36	GO:0005775	vacuolar lumen
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004553

sp|P06307|CCKN_HUMAN
Cholecystokinin
Search

CCK

0.97	Preprocholecystokinin

0.76	GO:0010469	regulation of receptor activity
0.61	GO:0042755	eating behavior
0.59	GO:0001764	neuron migration
0.57	GO:0007409	axonogenesis
0.43	GO:0031667	response to nutrient levels
0.43	GO:0014049	positive regulation of glutamate secretion
0.42	GO:0051901	positive regulation of mitochondrial depolarization
0.42	GO:0051930	regulation of sensory perception of pain
0.42	GO:0001836	release of cytochrome c from mitochondria
0.42	GO:0032096	negative regulation of response to food

0.79	GO:0005179	hormone activity
0.33	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.57	GO:0030424	axon
0.41	GO:0043204	perikaryon
0.41	GO:0043679	axon terminus
0.40	GO:0030425	dendrite
0.30	GO:0031224	intrinsic component of membrane

sp|P06310|KV230_HUMAN
Immunoglobulin kappa variable 2-30
Search

0.96	Myosin-reactive immunoglobulin light chain variable region (Fragment)

0.80	GO:0002377	immunoglobulin production
0.72	GO:0006955	immune response
0.54	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.53	GO:0038095	Fc-epsilon receptor signaling pathway
0.52	GO:0030449	regulation of complement activation
0.51	GO:0002449	lymphocyte mediated immunity
0.51	GO:0072376	protein activation cascade
0.50	GO:0050900	leukocyte migration
0.46	GO:0006898	receptor-mediated endocytosis
0.42	GO:0006508	proteolysis

0.58	GO:0003823	antigen binding
0.45	GO:0004252	serine-type endopeptidase activity
0.36	GO:0046872	metal ion binding

0.71	GO:0005615	extracellular space
0.44	GO:1903561	extracellular vesicle
0.43	GO:0005886	plasma membrane

0.45

GO:0004252

sp|P06312|KV401_HUMAN
Immunoglobulin kappa variable 4-1
Search

0.97	Anti-staphylococcal enterotoxin D variable region kappa chain (Fragment)

0.79	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.65	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.64	GO:0038095	Fc-epsilon receptor signaling pathway
0.62	GO:0030449	regulation of complement activation
0.61	GO:0002449	lymphocyte mediated immunity
0.60	GO:0072376	protein activation cascade
0.60	GO:0050900	leukocyte migration
0.54	GO:0006898	receptor-mediated endocytosis
0.48	GO:0003094	glomerular filtration

0.71	GO:0003823	antigen binding
0.52	GO:0004252	serine-type endopeptidase activity

0.72	GO:0005615	extracellular space
0.55	GO:1903561	extracellular vesicle
0.50	GO:0071745	IgA immunoglobulin complex
0.49	GO:0071753	IgM immunoglobulin complex
0.48	GO:0005886	plasma membrane

0.52

GO:0004252

sp|P06315|KV502_HUMAN
Immunoglobulin kappa variable 5-2
Search

0.97	Ig kappa chain V-I region Walker

0.76	GO:0002377	immunoglobulin production
0.70	GO:0006955	immune response
0.52	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.52	GO:0038095	Fc-epsilon receptor signaling pathway
0.51	GO:0030449	regulation of complement activation
0.49	GO:0002449	lymphocyte mediated immunity
0.49	GO:0072376	protein activation cascade
0.49	GO:0050900	leukocyte migration
0.45	GO:0006898	receptor-mediated endocytosis
0.42	GO:0042100	B cell proliferation

0.63	GO:0003823	antigen binding
0.44	GO:0004252	serine-type endopeptidase activity
0.37	GO:0042802	identical protein binding
0.36	GO:0004872	receptor activity

0.67	GO:0005615	extracellular space
0.45	GO:1903561	extracellular vesicle
0.42	GO:0005886	plasma membrane
0.37	GO:0009986	cell surface
0.37	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

0.44

GO:0004252

sp|P06331|HV434_HUMAN
Immunoglobulin heavy variable 4-34
Search

0.88	Immunoglobulin heavy variable 4-4

0.83	GO:0002250	adaptive immune response
0.75	GO:0002449	lymphocyte mediated immunity
0.75	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.75	GO:0006956	complement activation
0.74	GO:0006909	phagocytosis
0.65	GO:0099024	plasma membrane invagination
0.65	GO:0050871	positive regulation of B cell activation
0.63	GO:0038094	Fc-gamma receptor signaling pathway
0.63	GO:0038095	Fc-epsilon receptor signaling pathway
0.62	GO:0008037	cell recognition

0.85	GO:0003823	antigen binding
0.67	GO:0034987	immunoglobulin receptor binding
0.51	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005576	extracellular region
0.66	GO:0019814	immunoglobulin complex
0.63	GO:0009897	external side of plasma membrane
0.43	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

0.51

GO:0004252

sp|P06340|DOA_HUMAN
HLA class II histocompatibility antigen, DO alpha chain
Search

0.40	Major histocompatability complex class II

0.80	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.66	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.64	GO:0045580	regulation of T cell differentiation
0.49	GO:0002587	negative regulation of antigen processing and presentation of peptide antigen via MHC class II
0.39	GO:0065006	protein-carbohydrate complex assembly
0.39	GO:0002399	MHC class II protein complex assembly
0.39	GO:0002501	peptide antigen assembly with MHC protein complex
0.37	GO:0050890	cognition
0.36	GO:0045621	positive regulation of lymphocyte differentiation

0.54	GO:0023026	MHC class II protein complex binding
0.40	GO:0042605	peptide antigen binding
0.36	GO:0032395	MHC class II receptor activity

0.75	GO:0042613	MHC class II protein complex
0.39	GO:0005764	lysosome
0.38	GO:0098852	lytic vacuole membrane
0.38	GO:0010008	endosome membrane
0.38	GO:0009986	cell surface
0.37	GO:0005770	late endosome
0.35	GO:0098552	side of membrane
0.34	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

sp|P06396|GELS_HUMAN
Gelsolin
Search

GSN

0.74	Actin-depolymerizing factor

0.84	GO:0051014	actin filament severing
0.84	GO:0051016	barbed-end actin filament capping
0.80	GO:0045010	actin nucleation
0.59	GO:1903923	positive regulation of protein processing in phagocytic vesicle
0.57	GO:0097017	renal protein absorption
0.57	GO:1902174	positive regulation of keratinocyte apoptotic process
0.56	GO:0014891	striated muscle atrophy
0.56	GO:1990000	amyloid fibril formation
0.56	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.56	GO:0097284	hepatocyte apoptotic process

0.78	GO:0051015	actin filament binding
0.70	GO:0005509	calcium ion binding
0.56	GO:0045159	myosin II binding

0.56	GO:0030478	actin cap
0.54	GO:0002102	podosome
0.53	GO:0005925	focal adhesion
0.53	GO:0016528	sarcoplasm
0.52	GO:0045335	phagocytic vesicle
0.52	GO:0030027	lamellipodium
0.48	GO:0005615	extracellular space
0.47	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane

sp|P06400|RB_HUMAN
Retinoblastoma-associated protein
Search

RB1

0.96	RB transcriptional corepressor 1

0.85	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.79	GO:0008285	negative regulation of cell proliferation
0.78	GO:0006915	apoptotic process
0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.61	GO:0043353	enucleate erythrocyte differentiation
0.61	GO:0045651	positive regulation of macrophage differentiation
0.60	GO:0071922	regulation of cohesin loading
0.60	GO:0034088	maintenance of mitotic sister chromatid cohesion
0.59	GO:0045445	myoblast differentiation

0.73	GO:0008134	transcription factor binding
0.60	GO:0061676	importin-alpha family protein binding
0.58	GO:0097718	disordered domain specific binding
0.57	GO:0051219	phosphoprotein binding
0.56	GO:0001047	core promoter binding
0.54	GO:0019900	kinase binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042802	identical protein binding
0.35	GO:0051427	hormone receptor binding
0.35	GO:0003713	transcription coactivator activity

0.86	GO:0035189	Rb-E2F complex
0.59	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.58	GO:0016605	PML body
0.54	GO:0005819	spindle
0.35	GO:0016514	SWI/SNF complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P06401|PRGR_HUMAN
Progesterone receptor
Search

PGR

0.96	Progesterone receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis
0.57	GO:0038001	paracrine signaling
0.57	GO:0001542	ovulation from ovarian follicle
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0002070	epithelial cell maturation
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048286	lung alveolus development

0.79	GO:0003707	steroid hormone receptor activity
0.74	GO:0005496	steroid binding
0.62	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.59	GO:0003700	DNA binding transcription factor activity
0.56	GO:0051117	ATPase binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0042802	identical protein binding
0.49	GO:0003690	double-stranded DNA binding
0.38	GO:0042562	hormone binding

0.61	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.36	GO:0043204	perikaryon
0.36	GO:0043197	dendritic spine
0.36	GO:0043679	axon terminus
0.36	GO:0031968	organelle outer membrane
0.36	GO:0030424	axon
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0012505	endomembrane system
0.34	GO:0043235	receptor complex

sp|P06454|PTMA_HUMAN
Prothymosin alpha
Search

PTMA

0.96	Prothymosin alpha

0.61	GO:0043486	histone exchange
0.41	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.40	GO:0008283	cell proliferation
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0030154	cell differentiation
0.38	GO:0016024	CDP-diacylglycerol biosynthetic process
0.38	GO:0032049	cardiolipin biosynthetic process
0.36	GO:0006351	transcription, DNA-templated

0.66	GO:0033613	activating transcription factor binding
0.59	GO:0042393	histone binding
0.39	GO:0035091	phosphatidylinositol binding
0.38	GO:0004605	phosphatidate cytidylyltransferase activity
0.35	GO:0003676	nucleic acid binding

0.59	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol
0.45	GO:0070062	extracellular exosome
0.37	GO:0031011	Ino80 complex
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

0.38

EC:2.7.7.41

GO:0004605

sp|P06493|CDK1_HUMAN
Cyclin-dependent kinase 1
Search

CDK1

0.87	LOW QUALITY PROTEIN: cyclin-dependent kinase 1

0.63	GO:0006468	protein phosphorylation
0.55	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.53	GO:0051726	regulation of cell cycle
0.53	GO:0044772	mitotic cell cycle phase transition
0.52	GO:0034501	protein localization to kinetochore
0.52	GO:0018210	peptidyl-threonine modification
0.51	GO:1900182	positive regulation of protein localization to nucleus
0.51	GO:0018209	peptidyl-serine modification
0.50	GO:0016570	histone modification
0.50	GO:0030855	epithelial cell differentiation

0.66	GO:0004674	protein serine/threonine kinase activity
0.58	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0035173	histone kinase activity
0.52	GO:0030544	Hsp70 protein binding
0.51	GO:0030332	cyclin binding
0.48	GO:0003682	chromatin binding

0.56	GO:0097125	cyclin B1-CDK1 complex
0.53	GO:0072686	mitotic spindle
0.51	GO:0030496	midbody
0.51	GO:0005876	spindle microtubule
0.51	GO:0005815	microtubule organizing center
0.48	GO:0005759	mitochondrial matrix
0.46	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:0000781	chromosome, telomeric region

0.66

GO:0004674

sp|P06576|ATPB_HUMAN
ATP synthase subunit beta, mitochondrial
Search

ATP5B

0.43	Mitochondrial ATP synthase subunit beta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.54	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration
0.53	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.51	GO:0051453	regulation of intracellular pH
0.51	GO:0001525	angiogenesis
0.43	GO:0006629	lipid metabolic process
0.37	GO:0001649	osteoblast differentiation
0.35	GO:0042407	cristae formation

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0043532	angiostatin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0042288	MHC class I protein binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.35	GO:0030228	lipoprotein particle receptor activity
0.34	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0042645	mitochondrial nucleoid
0.50	GO:0043209	myelin sheath
0.49	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.48	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0045121	membrane raft

sp|P06681|CO2_HUMAN
Complement C2
Search

0.96	Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment

0.81	GO:0006956	complement activation
0.77	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.61	GO:0006508	proteolysis
0.51	GO:2000427	positive regulation of apoptotic cell clearance
0.45	GO:0045087	innate immune response
0.43	GO:0007584	response to nutrient
0.37	GO:0009617	response to bacterium
0.37	GO:0097066	response to thyroid hormone
0.37	GO:0030449	regulation of complement activation
0.36	GO:0033993	response to lipid

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005515	protein binding
0.37	GO:0046872	metal ion binding
0.35	GO:0005044	scavenger receptor activity
0.32	GO:0004930	G-protein coupled receptor activity
0.31	GO:0016301	kinase activity

0.62	GO:0005576	extracellular region
0.39	GO:0031982	vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P06702|S10A9_HUMAN
Protein S100-A9
Search

S100A9

0.95	Calcium-binding protein A9

0.79	GO:0050727	regulation of inflammatory response
0.77	GO:0045087	innate immune response
0.76	GO:0070488	neutrophil aggregation
0.74	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.73	GO:0002523	leukocyte migration involved in inflammatory response
0.70	GO:0030593	neutrophil chemotaxis
0.70	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.70	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.69	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.66	GO:0032103	positive regulation of response to external stimulus

0.86	GO:0035662	Toll-like receptor 4 binding
0.86	GO:0050544	arachidonic acid binding
0.85	GO:0050786	RAGE receptor binding
0.72	GO:0008017	microtubule binding
0.70	GO:0005509	calcium ion binding
0.61	GO:0008270	zinc ion binding
0.42	GO:0016209	antioxidant activity
0.38	GO:0005507	copper ion binding
0.36	GO:0004871	signal transducer activity

0.60	GO:0030054	cell junction
0.59	GO:0005615	extracellular space
0.56	GO:0005654	nucleoplasm
0.56	GO:0005829	cytosol
0.42	GO:0005856	cytoskeleton
0.41	GO:0031012	extracellular matrix
0.41	GO:1903561	extracellular vesicle
0.40	GO:0034774	secretory granule lumen
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P06703|S10A6_HUMAN
Protein S100-A6
Search

0.92	S100 calcium binding protein A6

0.43	GO:0048168	regulation of neuronal synaptic plasticity
0.43	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.43	GO:0007613	memory
0.42	GO:0042127	regulation of cell proliferation
0.38	GO:0048708	astrocyte differentiation
0.38	GO:0031643	positive regulation of myelination
0.38	GO:0051597	response to methylmercury
0.38	GO:2001015	negative regulation of skeletal muscle cell differentiation
0.38	GO:0060291	long-term synaptic potentiation
0.38	GO:0051384	response to glucocorticoid

0.70	GO:0005509	calcium ion binding
0.61	GO:0048306	calcium-dependent protein binding
0.59	GO:0044548	S100 protein binding
0.58	GO:0042803	protein homodimerization activity
0.55	GO:0005523	tropomyosin binding
0.54	GO:0046914	transition metal ion binding
0.45	GO:0050786	RAGE receptor binding
0.38	GO:0048156	tau protein binding
0.37	GO:0019899	enzyme binding
0.36	GO:0005198	structural molecule activity

0.57	GO:0001726	ruffle
0.55	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.52	GO:0043025	neuronal cell body
0.51	GO:0005635	nuclear envelope
0.48	GO:0005829	cytosol
0.47	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.34	GO:0036457	keratohyalin granule
0.33	GO:0001533	cornified envelope

sp|P06727|APOA4_HUMAN
Apolipoprotein A-IV
Search

APOA4

0.97	Apolipoprotein A-IV

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.68	GO:0034372	very-low-density lipoprotein particle remodeling
0.68	GO:0051006	positive regulation of lipoprotein lipase activity
0.68	GO:0010873	positive regulation of cholesterol esterification
0.68	GO:0034444	regulation of plasma lipoprotein oxidation
0.68	GO:0006982	response to lipid hydroperoxide
0.68	GO:0044240	multicellular organismal lipid catabolic process
0.67	GO:0045723	positive regulation of fatty acid biosynthetic process
0.67	GO:0010898	positive regulation of triglyceride catabolic process

0.72	GO:0008289	lipid binding
0.69	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.67	GO:0050997	quaternary ammonium group binding
0.66	GO:0017127	cholesterol transporter activity
0.63	GO:0070405	ammonium ion binding
0.57	GO:0042803	protein homodimerization activity
0.55	GO:0005507	copper ion binding
0.53	GO:0016209	antioxidant activity
0.49	GO:0043178	alcohol binding
0.44	GO:0043168	anion binding

0.68	GO:0042627	chylomicron
0.67	GO:0034364	high-density lipoprotein particle
0.64	GO:0034361	very-low-density lipoprotein particle
0.57	GO:0009986	cell surface
0.56	GO:0031012	extracellular matrix
0.51	GO:0072562	blood microparticle
0.38	GO:0070062	extracellular exosome
0.38	GO:0005788	endoplasmic reticulum lumen
0.38	GO:0005769	early endosome
0.37	GO:0005829	cytosol

sp|P06729|CD2_HUMAN
T-cell surface antigen CD2
Search

CD2

0.93	T-lymphocyte surface CD2 antigen

0.77	GO:1902715	positive regulation of interferon-gamma secretion
0.75	GO:2000484	positive regulation of interleukin-8 secretion
0.74	GO:0034113	heterotypic cell-cell adhesion
0.72	GO:0032760	positive regulation of tumor necrosis factor production
0.44	GO:0030887	positive regulation of myeloid dendritic cell activation
0.43	GO:0042110	T cell activation
0.42	GO:0001766	membrane raft polarization
0.41	GO:0030101	natural killer cell activation
0.41	GO:0045580	regulation of T cell differentiation
0.40	GO:0050900	leukocyte migration

0.62	GO:0005102	receptor binding
0.54	GO:0042803	protein homodimerization activity
0.38	GO:0003823	antigen binding
0.38	GO:0043621	protein self-association
0.38	GO:1990782	protein tyrosine kinase binding
0.37	GO:0004872	receptor activity

0.70	GO:0009897	external side of plasma membrane
0.58	GO:0046658	anchored component of plasma membrane
0.55	GO:0005911	cell-cell junction
0.55	GO:0009898	cytoplasmic side of plasma membrane
0.50	GO:0005576	extracellular region
0.37	GO:0045121	membrane raft
0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0043234	protein complex

sp|P06730|IF4E_HUMAN
Eukaryotic translation initiation factor 4E
Search

EIF4E

0.79	Eukaryotic translation initiation factor 4E

0.72	GO:0006413	translational initiation
0.52	GO:0071549	cellular response to dexamethasone stimulus
0.52	GO:0001662	behavioral fear response
0.50	GO:0019827	stem cell population maintenance
0.50	GO:0045665	negative regulation of neuron differentiation
0.48	GO:0000082	G1/S transition of mitotic cell cycle
0.48	GO:0017148	negative regulation of translation
0.47	GO:0045931	positive regulation of mitotic cell cycle
0.39	GO:0030324	lung development
0.35	GO:0010507	negative regulation of autophagy

0.73	GO:0003743	translation initiation factor activity
0.72	GO:0031370	eukaryotic initiation factor 4G binding
0.69	GO:0070491	repressing transcription factor binding
0.59	GO:0019899	enzyme binding
0.50	GO:0000340	RNA 7-methylguanosine cap binding

0.64	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005845	mRNA cap binding complex
0.52	GO:0033391	chromatoid body
0.51	GO:0016281	eukaryotic translation initiation factor 4F complex
0.48	GO:0016442	RISC complex
0.47	GO:0000932	P-body
0.47	GO:0010494	cytoplasmic stress granule
0.44	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

sp|P06731|CEAM5_HUMAN
Carcinoembryonic antigen-related cell adhesion molecule 5
Search

0.10	Carcinoembryonic antigen-related cell adhesion molecule 5

0.47	GO:0007565	female pregnancy
0.45	GO:0016477	cell migration
0.44	GO:0043312	neutrophil degranulation
0.42	GO:0043317	regulation of cytotoxic T cell degranulation
0.41	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.41	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.41	GO:0030334	regulation of cell migration
0.41	GO:0043301	negative regulation of leukocyte degranulation
0.40	GO:0050860	negative regulation of T cell receptor signaling pathway
0.40	GO:0090505	epiboly involved in wound healing

0.42	GO:0031005	filamin binding
0.41	GO:1990782	protein tyrosine kinase binding
0.41	GO:0019903	protein phosphatase binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0003779	actin binding
0.37	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.37	GO:0034235	GPI anchor binding
0.37	GO:0046790	virion binding
0.37	GO:0035325	Toll-like receptor binding
0.37	GO:0001618	virus receptor activity

0.44	GO:0035579	specific granule membrane
0.42	GO:0042101	T cell receptor complex
0.40	GO:0009986	cell surface
0.40	GO:0005576	extracellular region
0.39	GO:0005911	cell-cell junction
0.38	GO:0098552	side of membrane
0.38	GO:0016323	basolateral plasma membrane
0.37	GO:0031225	anchored component of membrane
0.37	GO:0031528	microvillus membrane
0.36	GO:0031526	brush border membrane

sp|P06732|KCRM_HUMAN
Creatine kinase M-type
Search

CKM

0.94	Cytoplasmic creatine kinases

0.57	GO:0046314	phosphocreatine biosynthetic process
0.57	GO:0016310	phosphorylation
0.49	GO:0009408	response to heat
0.35	GO:0006600	creatine metabolic process
0.35	GO:0030644	cellular chloride ion homeostasis
0.34	GO:0007420	brain development
0.33	GO:0006754	ATP biosynthetic process

0.68	GO:0004111	creatine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0031625	ubiquitin protein ligase binding

0.51	GO:0005615	extracellular space
0.39	GO:0043209	myelin sheath
0.38	GO:0005829	cytosol
0.36	GO:0005739	mitochondrion
0.35	GO:0065010	extracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.68	EC:2.7.3.2	GO:0004111
0.68	KEGG:R01881	GO:0004111

sp|P06733|ENOA_HUMAN
Alpha-enolase
Search

ENO1

0.71	Alpha-enolase

0.71	GO:0006096	glycolytic process
0.51	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.51	GO:0010756	positive regulation of plasminogen activation
0.51	GO:0061718	glucose catabolic process to pyruvate
0.51	GO:2001171	positive regulation of ATP biosynthetic process
0.51	GO:0006735	NADH regeneration
0.50	GO:1900038	negative regulation of cellular response to hypoxia
0.49	GO:0045933	positive regulation of muscle contraction
0.49	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.48	GO:0030308	negative regulation of cell growth

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.49	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0045296	cadherin binding
0.46	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.46	GO:0042803	protein homodimerization activity
0.45	GO:0051020	GTPase binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0003723	RNA binding
0.35	GO:0005212	structural constituent of eye lens

0.77	GO:0000015	phosphopyruvate hydratase complex
0.48	GO:0099738	cell cortex region
0.46	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.39	GO:0043209	myelin sheath
0.37	GO:0019898	extrinsic component of membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0097458	neuron part
0.35	GO:0031430	M band
0.34	GO:0044297	cell body

0.78

EC:4.2.1.11

GO:0004634

sp|P06734|FCER2_HUMAN
Low affinity immunoglobulin epsilon Fc receptor
Search

FCER2

0.96	Low affinity immunoglobulin epsilon Fc receptor

0.69	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin
0.68	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
0.67	GO:0051000	positive regulation of nitric-oxide synthase activity
0.62	GO:0051712	positive regulation of killing of cells of other organism
0.42	GO:1905226	regulation of adhesion of symbiont to host epithelial cell
0.41	GO:0043152	induction of bacterial agglutination
0.41	GO:0052405	negative regulation by host of symbiont molecular function
0.41	GO:0043129	surfactant homeostasis
0.40	GO:0048286	lung alveolus development
0.40	GO:0007219	Notch signaling pathway

0.68	GO:0030246	carbohydrate binding
0.44	GO:0019863	IgE binding
0.40	GO:0005178	integrin binding
0.36	GO:0046872	metal ion binding
0.36	GO:0042802	identical protein binding
0.35	GO:0005518	collagen binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0001530	lipopolysaccharide binding
0.33	GO:0020037	heme binding
0.33	GO:0046983	protein dimerization activity

0.62	GO:0009897	external side of plasma membrane
0.46	GO:0070062	extracellular exosome
0.44	GO:0005581	collagen trimer
0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0005771	multivesicular body
0.33	GO:0005791	rough endoplasmic reticulum

0.34

GO:0016705

sp|P06737|PYGL_HUMAN
Glycogen phosphorylase, liver form
Search

PYGL

0.50	Alpha-1,4 glucan phosphorylase

0.60	GO:0005975	carbohydrate metabolic process
0.53	GO:0070266	necroptotic process
0.51	GO:0006112	energy reserve metabolic process
0.50	GO:0042593	glucose homeostasis
0.41	GO:0009057	macromolecule catabolic process
0.40	GO:0044248	cellular catabolic process
0.39	GO:0044260	cellular macromolecule metabolic process

0.80	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.80	GO:0102499	SHG alpha-glucan phosphorylase activity
0.79	GO:0008184	glycogen phosphorylase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.55	GO:0002060	purine nucleobase binding
0.53	GO:0032052	bile acid binding
0.49	GO:0016208	AMP binding
0.40	GO:0005524	ATP binding

0.40	GO:0045177	apical part of cell
0.40	GO:0048471	perinuclear region of cytoplasm

sp|P06744|G6PI_HUMAN
Glucose-6-phosphate isomerase
Search

GPI

0.53	Glucose-6-phosphate isomerase

0.73	GO:0019319	hexose biosynthetic process
0.71	GO:0006006	glucose metabolic process
0.71	GO:0006096	glycolytic process
0.56	GO:0051024	positive regulation of immunoglobulin secretion
0.53	GO:0001707	mesoderm formation
0.53	GO:0034101	erythrocyte homeostasis
0.51	GO:0042593	glucose homeostasis
0.49	GO:0001701	in utero embryonic development
0.43	GO:0001525	angiogenesis
0.41	GO:0010469	regulation of receptor activity

0.78	GO:0004347	glucose-6-phosphate isomerase activity
0.51	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0005125	cytokine activity
0.37	GO:0008083	growth factor activity
0.37	GO:0048029	monosaccharide binding
0.36	GO:0016866	intramolecular transferase activity

0.54	GO:0060170	ciliary membrane
0.52	GO:0043209	myelin sheath
0.49	GO:0005615	extracellular space
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.37	GO:0043005	neuron projection
0.36	GO:1903561	extracellular vesicle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.78

EC:5.3.1.9

GO:0004347

sp|P06746|DPOLB_HUMAN
DNA polymerase beta
Search

POLB

0.90	LOW QUALITY PROTEIN: DNA polymerase beta

0.65	GO:0071897	DNA biosynthetic process
0.63	GO:0006281	DNA repair
0.59	GO:0071707	immunoglobulin heavy chain V-D-J recombination
0.56	GO:0016446	somatic hypermutation of immunoglobulin genes
0.56	GO:0048535	lymph node development
0.55	GO:0048536	spleen development
0.55	GO:0051402	neuron apoptotic process
0.54	GO:0007435	salivary gland morphogenesis
0.54	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.52	GO:0006954	inflammatory response

0.68	GO:0003887	DNA-directed DNA polymerase activity
0.53	GO:0003677	DNA binding
0.51	GO:0008017	microtubule binding
0.49	GO:0019899	enzyme binding
0.45	GO:0016829	lyase activity
0.35	GO:0046872	metal ion binding

0.59	GO:0005634	nucleus
0.54	GO:0005876	spindle microtubule
0.44	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0000793	condensed chromosome
0.34	GO:0044427	chromosomal part
0.30	GO:0016020	membrane

0.68

GO:0003887

sp|P06748|NPM_HUMAN
Nucleophosmin
Search

NPM1

0.93	Nucleophosmin

0.51	GO:0060735	regulation of eIF2 alpha phosphorylation by dsRNA
0.49	GO:0010824	regulation of centrosome duplication
0.49	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.48	GO:0032071	regulation of endodeoxyribonuclease activity
0.47	GO:0090068	positive regulation of cell cycle process
0.47	GO:0007569	cell aging
0.47	GO:0007098	centrosome cycle
0.47	GO:1904751	positive regulation of protein localization to nucleolus
0.47	GO:0042127	regulation of cell proliferation
0.47	GO:0060699	regulation of endoribonuclease activity

0.50	GO:0003676	nucleic acid binding
0.49	GO:0051059	NF-kappaB binding
0.48	GO:0030957	Tat protein binding
0.47	GO:0043024	ribosomal small subunit binding
0.46	GO:0001105	RNA polymerase II transcription coactivator activity
0.46	GO:0004860	protein kinase inhibitor activity
0.46	GO:0033613	activating transcription factor binding
0.45	GO:0047485	protein N-terminus binding
0.45	GO:0019901	protein kinase binding
0.44	GO:0042393	histone binding

0.47	GO:0031616	spindle pole centrosome
0.46	GO:0001652	granular component
0.44	GO:0005654	nucleoplasm
0.42	GO:0032993	protein-DNA complex
0.41	GO:0005829	cytosol
0.41	GO:0015934	large ribosomal subunit
0.41	GO:0015935	small ribosomal subunit
0.39	GO:0016363	nuclear matrix
0.39	GO:0043234	protein complex
0.37	GO:0005925	focal adhesion

sp|P06753|TPM3_HUMAN
Tropomyosin alpha-3 chain
Search

TPM3

0.76	Alpha-tropomyosin

0.68	GO:0006936	muscle contraction
0.62	GO:0007015	actin filament organization
0.46	GO:0061515	myeloid cell development
0.46	GO:0060047	heart contraction
0.43	GO:0033275	actin-myosin filament sliding
0.40	GO:0043462	regulation of ATPase activity
0.40	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.39	GO:0018108	peptidyl-tyrosine phosphorylation

0.72	GO:0008307	structural constituent of muscle
0.65	GO:0051015	actin filament binding
0.40	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity
0.38	GO:0008017	microtubule binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005862	muscle thin filament tropomyosin
0.74	GO:0097517	contractile actin filament bundle
0.73	GO:0042641	actomyosin
0.68	GO:0005884	actin filament
0.61	GO:0005829	cytosol
0.42	GO:0002102	podosome
0.42	GO:0032154	cleavage furrow
0.42	GO:0030426	growth cone
0.41	GO:0070062	extracellular exosome
0.41	GO:0030863	cortical cytoskeleton

0.40

GO:0004714

sp|P06756|ITAV_HUMAN
Integrin alpha-V
Search

ITGAV

0.89	Alpha v integrin subunit variant

0.78	GO:0007229	integrin-mediated signaling pathway
0.71	GO:0007155	cell adhesion
0.65	GO:2000536	negative regulation of entry of bacterium into host cell
0.64	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process
0.64	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.63	GO:0038044	transforming growth factor-beta secretion
0.63	GO:0050748	negative regulation of lipoprotein metabolic process
0.63	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.62	GO:0010888	negative regulation of lipid storage
0.61	GO:0032369	negative regulation of lipid transport

0.64	GO:1990430	extracellular matrix protein binding
0.64	GO:0038132	neuregulin binding
0.63	GO:0019960	C-X3-C chemokine binding
0.62	GO:0031994	insulin-like growth factor I binding
0.62	GO:0001968	fibronectin binding
0.61	GO:0001846	opsonin binding
0.61	GO:0017134	fibroblast growth factor binding
0.60	GO:0005080	protein kinase C binding
0.59	GO:0005178	integrin binding
0.59	GO:0050840	extracellular matrix binding

0.79	GO:0008305	integrin complex
0.64	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.63	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.62	GO:0031258	lamellipodium membrane
0.62	GO:0031528	microvillus membrane
0.62	GO:0031527	filopodium membrane
0.60	GO:0032587	ruffle membrane
0.59	GO:0005925	focal adhesion
0.57	GO:0009897	external side of plasma membrane
0.50	GO:0005829	cytosol

sp|P06850|CRF_HUMAN
Corticoliberin
Search

CRH

0.97	Corticotropin-releasing factor b

0.75	GO:0010469	regulation of receptor activity
0.67	GO:2000851	positive regulation of glucocorticoid secretion
0.66	GO:0051461	positive regulation of corticotropin secretion
0.66	GO:0051462	regulation of cortisol secretion
0.64	GO:0001963	synaptic transmission, dopaminergic
0.63	GO:1900449	regulation of glutamate receptor signaling pathway
0.63	GO:2001025	positive regulation of response to drug
0.61	GO:0006704	glucocorticoid biosynthetic process
0.61	GO:2001257	regulation of cation channel activity
0.60	GO:0035641	locomotory exploration behavior

0.79	GO:0005179	hormone activity
0.44	GO:0051430	corticotropin-releasing hormone receptor 1 binding
0.44	GO:0051431	corticotropin-releasing hormone receptor 2 binding
0.33	GO:0004601	peroxidase activity
0.33	GO:0004849	uridine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding

0.66	GO:0005576	extracellular region
0.44	GO:0043196	varicosity
0.42	GO:0043204	perikaryon
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33	EC:1.11.1.7	GO:0004601
0.33	KEGG:R03532	GO:0004601

sp|P06858|LIPL_HUMAN
Lipoprotein lipase
Search

LPL

0.93	Lipoprotein lipase

0.70	GO:0016042	lipid catabolic process
0.61	GO:0009749	response to glucose
0.59	GO:0055096	low-density lipoprotein particle mediated signaling
0.58	GO:0010886	positive regulation of cholesterol storage
0.58	GO:0010890	positive regulation of sequestering of triglyceride
0.58	GO:0034372	very-low-density lipoprotein particle remodeling
0.57	GO:0090197	positive regulation of chemokine secretion
0.56	GO:0070328	triglyceride homeostasis
0.55	GO:0019432	triglyceride biosynthetic process
0.55	GO:0042632	cholesterol homeostasis

0.86	GO:0004465	lipoprotein lipase activity
0.79	GO:0008201	heparin binding
0.57	GO:0034185	apolipoprotein binding
0.49	GO:0005102	receptor binding
0.41	GO:0017129	triglyceride binding
0.36	GO:0004620	phospholipase activity

0.84	GO:0042627	chylomicron
0.84	GO:0034361	very-low-density lipoprotein particle
0.76	GO:0031225	anchored component of membrane
0.54	GO:0005886	plasma membrane
0.48	GO:0009986	cell surface
0.38	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.86

EC:3.1.1.34

GO:0004465

sp|P06865|HEXA_HUMAN
Beta-hexosaminidase subunit alpha
Search

HEXA

0.48	Beta-hexosaminidase subunit alpha

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0006689	ganglioside catabolic process
0.56	GO:0050885	neuromuscular process controlling balance
0.55	GO:0050884	neuromuscular process controlling posture
0.55	GO:0042552	myelination
0.55	GO:0007040	lysosome organization
0.55	GO:0019915	lipid storage
0.54	GO:0007628	adult walking behavior
0.54	GO:0060395	SMAD protein signal transduction
0.54	GO:0007605	sensory perception of sound

0.78	GO:0004563	beta-N-acetylhexosaminidase activity
0.70	GO:0102148	N-acetyl-beta-D-galactosaminidase activity
0.41	GO:0008375	acetylglucosaminyltransferase activity
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0042803	protein homodimerization activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.53	GO:0005764	lysosome
0.42	GO:0030141	secretory granule
0.40	GO:0097223	sperm part
0.40	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005775	vacuolar lumen
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.2.1.52

GO:0004563

sp|P06870|KLK1_HUMAN
Kallikrein-1
Search

0.97	Epidermal growth factor-binding protein type B

0.61	GO:0006508	proteolysis
0.41	GO:0002778	antibacterial peptide production
0.38	GO:0002675	positive regulation of acute inflammatory response
0.37	GO:0007584	response to nutrient
0.37	GO:0008284	positive regulation of cell proliferation
0.37	GO:0043065	positive regulation of apoptotic process
0.36	GO:0003073	regulation of systemic arterial blood pressure
0.36	GO:0002936	bradykinin biosynthetic process
0.36	GO:0002255	tissue kallikrein-kinin cascade
0.36	GO:0009405	pathogenesis

0.69	GO:0004252	serine-type endopeptidase activity
0.40	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.36	GO:0090729	toxin activity
0.36	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0008083	growth factor activity
0.34	GO:0005509	calcium ion binding

0.45	GO:0005615	extracellular space
0.41	GO:0005634	nucleus
0.40	GO:1903561	extracellular vesicle
0.39	GO:0030141	secretory granule
0.38	GO:0043234	protein complex
0.37	GO:0097223	sperm part
0.37	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P06899|H2B1J_HUMAN
Histone H2B type 1-J
Search

0.92	Histone H2B type 1-J

0.48	GO:0002227	innate immune response in mucosa
0.48	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.47	GO:0019731	antibacterial humoral response
0.47	GO:0006334	nucleosome assembly
0.47	GO:0050830	defense response to Gram-positive bacterium
0.44	GO:0050829	defense response to Gram-negative bacterium
0.43	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.43	GO:0031640	killing of cells of other organism
0.35	GO:0016567	protein ubiquitination
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.42	GO:0001530	lipopolysaccharide binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0005615	extracellular space
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P07093|GDN_HUMAN
Glia-derived nexin
Search

SERPINE2

0.97	Serine protease inhibitor clade E member 2

0.60	GO:0061108	seminal vesicle epithelium development
0.60	GO:0042628	mating plug formation
0.60	GO:0010757	negative regulation of plasminogen activation
0.58	GO:0090331	negative regulation of platelet aggregation
0.58	GO:0021683	cerebellar granular layer morphogenesis
0.58	GO:0010766	negative regulation of sodium ion transport
0.58	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.58	GO:0048505	regulation of timing of cell differentiation
0.58	GO:0048711	positive regulation of astrocyte differentiation
0.57	GO:0060384	innervation

0.55	GO:0004867	serine-type endopeptidase inhibitor activity
0.54	GO:0008201	heparin binding
0.50	GO:0005102	receptor binding
0.37	GO:0002020	protease binding
0.36	GO:0008233	peptidase activity
0.35	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.32	GO:0046872	metal ion binding

0.73	GO:0005615	extracellular space
0.58	GO:0031232	extrinsic component of external side of plasma membrane
0.57	GO:0031091	platelet alpha granule
0.55	GO:0031594	neuromuscular junction
0.51	GO:0031012	extracellular matrix
0.48	GO:0005829	cytosol
0.38	GO:1903561	extracellular vesicle
0.35	GO:0043025	neuronal cell body
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005654	nucleoplasm

0.36

GO:0008233

sp|P07098|LIPG_HUMAN
Gastric triacylglycerol lipase
Search

0.48	Lysosomal acid lipase/cholesteryl ester hydrolase

0.46	GO:0048873	homeostasis of number of cells within a tissue
0.45	GO:0048771	tissue remodeling
0.45	GO:0001816	cytokine production
0.44	GO:0030324	lung development
0.44	GO:0016042	lipid catabolic process
0.44	GO:0006954	inflammatory response
0.43	GO:0008283	cell proliferation
0.42	GO:0000902	cell morphogenesis
0.42	GO:0034383	low-density lipoprotein particle clearance

0.60

GO:0016788

hydrolase activity, acting on ester bonds

0.47	GO:0001650	fibrillar center
0.43	GO:0005764	lysosome
0.41	GO:0005775	vacuolar lumen
0.40	GO:0070062	extracellular exosome

0.60

EC:3.1

GO:0016788

sp|P07099|HYEP_HUMAN
Epoxide hydrolase 1
Search

EPHX1

0.56	Epoxide hydrolase

0.59	GO:0019439	aromatic compound catabolic process
0.57	GO:0097176	epoxide metabolic process
0.46	GO:0014070	response to organic cyclic compound
0.37	GO:0009636	response to toxic substance
0.35	GO:0001889	liver development
0.35	GO:0070887	cellular response to chemical stimulus
0.34	GO:0009410	response to xenobiotic stimulus
0.34	GO:0034312	diol biosynthetic process
0.34	GO:0033993	response to lipid
0.34	GO:0009725	response to hormone

0.80	GO:0033961	cis-stilbene-oxide hydrolase activity
0.55	GO:0004301	epoxide hydrolase activity
0.34	GO:0019899	enzyme binding

0.63	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.3.2.9

GO:0033961

sp|P07101|TY3H_HUMAN
Tyrosine 3-monooxygenase
Search

0.87	Tyrosine hydroxylase

0.80	GO:0042423	catecholamine biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.62	GO:0007617	mating behavior
0.61	GO:0042417	dopamine metabolic process
0.58	GO:0042414	epinephrine metabolic process
0.56	GO:0001963	synaptic transmission, dopaminergic
0.56	GO:0035176	social behavior
0.56	GO:0042755	eating behavior
0.55	GO:0042415	norepinephrine metabolic process
0.55	GO:0007625	grooming behavior

0.84	GO:0004511	tyrosine 3-monooxygenase activity
0.62	GO:0005506	iron ion binding
0.47	GO:0019899	enzyme binding
0.41	GO:0004510	tryptophan 5-monooxygenase activity
0.40	GO:0034617	tetrahydrobiopterin binding
0.40	GO:0035240	dopamine binding
0.38	GO:0019825	oxygen binding
0.38	GO:0019904	protein domain specific binding
0.37	GO:0016597	amino acid binding
0.34	GO:0005179	hormone activity

0.55	GO:0033162	melanosome membrane
0.55	GO:0005790	smooth endoplasmic reticulum
0.55	GO:0043204	perikaryon
0.52	GO:0030424	axon
0.49	GO:0009898	cytoplasmic side of plasma membrane
0.44	GO:0005634	nucleus
0.39	GO:0043679	axon terminus
0.38	GO:0008021	synaptic vesicle
0.38	GO:0030425	dendrite
0.36	GO:0005829	cytosol

0.84

EC:1.14.16.2

GO:0004511

sp|P07108|ACBP_HUMAN
Acyl-CoA-binding protein
Search

DBI

0.61	Diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

0.48	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.35	GO:0018345	protein palmitoylation
0.34	GO:0042742	defense response to bacterium
0.34	GO:0035383	thioester metabolic process
0.33	GO:0006732	coenzyme metabolic process

0.82	GO:0000062	fatty-acyl-CoA binding
0.41	GO:0046983	protein dimerization activity
0.39	GO:0008289	lipid binding
0.35	GO:0030156	benzodiazepine receptor binding

0.39	GO:0005794	Golgi apparatus
0.39	GO:0005783	endoplasmic reticulum
0.35	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005911	cell-cell junction
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P07148|FABPL_HUMAN
Fatty acid-binding protein, liver
Search

FABP1

0.84	Fatty acid-binding protein, liver

0.57	GO:0070301	cellular response to hydrogen peroxide
0.57	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:0071456	cellular response to hypoxia
0.49	GO:0098869	cellular oxidant detoxification
0.42	GO:0032000	positive regulation of fatty acid beta-oxidation
0.42	GO:0050892	intestinal absorption
0.40	GO:0015909	long-chain fatty acid transport
0.39	GO:0051345	positive regulation of hydrolase activity
0.36	GO:0019433	triglyceride catabolic process
0.36	GO:0019082	viral protein processing

0.75	GO:0005504	fatty acid binding
0.68	GO:0032052	bile acid binding
0.52	GO:0003682	chromatin binding
0.49	GO:0016209	antioxidant activity
0.41	GO:0005324	long-chain fatty acid transporter activity
0.39	GO:0005543	phospholipid binding
0.36	GO:0051978	lysophospholipid transporter activity
0.35	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.41	GO:0045179	apical cortex
0.41	GO:0031907	microbody lumen
0.40	GO:0044439	peroxisomal part
0.37	GO:0070062	extracellular exosome
0.36	GO:0043234	protein complex

sp|P07195|LDHB_HUMAN
L-lactate dehydrogenase B chain
Search

LDHB

0.54	L-lactate dehydrogenase B chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.37	GO:0019674	NAD metabolic process
0.36	GO:1901615	organic hydroxy compound metabolic process
0.33	GO:0016053	organic acid biosynthetic process
0.32	GO:0006091	generation of precursor metabolites and energy
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0044260	cellular macromolecule metabolic process

0.81	GO:0004459	L-lactate dehydrogenase activity
0.48	GO:0042802	identical protein binding
0.38	GO:0019900	kinase binding
0.36	GO:0051287	NAD binding
0.35	GO:0005212	structural constituent of eye lens
0.34	GO:0004373	glycogen (starch) synthase activity

0.52	GO:0043209	myelin sheath
0.51	GO:0045121	membrane raft
0.48	GO:0005737	cytoplasm
0.41	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P07196|NFL_HUMAN
Neurofilament light polypeptide
Search

NEFL

0.97	Neurofilament light polypeptide

0.74	GO:0007399	nervous system development
0.72	GO:0120036	plasma membrane bounded cell projection organization
0.70	GO:0048468	cell development
0.63	GO:0060052	neurofilament cytoskeleton organization
0.62	GO:0045110	intermediate filament bundle assembly
0.61	GO:0019896	axonal transport of mitochondrion
0.61	GO:0008090	retrograde axonal transport
0.60	GO:0008089	anterograde axonal transport
0.58	GO:0032536	regulation of cell projection size
0.56	GO:0048678	response to axon injury

0.62	GO:0005198	structural molecule activity
0.57	GO:0008022	protein C-terminus binding
0.53	GO:0030674	protein binding, bridging
0.52	GO:0042802	identical protein binding
0.40	GO:0043274	phospholipase binding
0.38	GO:0019904	protein domain specific binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.85	GO:0005883	neurofilament
0.60	GO:0033596	TSC1-TSC2 complex
0.59	GO:1904115	axon cytoplasm
0.56	GO:0043209	myelin sheath
0.41	GO:0031965	nuclear membrane
0.41	GO:0036464	cytoplasmic ribonucleoprotein granule
0.39	GO:0005654	nucleoplasm
0.39	GO:0030426	growth cone
0.35	GO:0045098	type III intermediate filament

sp|P07197|NFM_HUMAN
Neurofilament medium polypeptide
Search

NEFM

0.91	Neurofilament medium polypeptide

0.76	GO:0061564	axon development
0.50	GO:0060052	neurofilament cytoskeleton organization
0.45	GO:1990830	cellular response to leukemia inhibitory factor
0.42	GO:0045110	intermediate filament bundle assembly
0.39	GO:0031133	regulation of axon diameter
0.38	GO:0008088	axo-dendritic transport
0.37	GO:0045105	intermediate filament polymerization or depolymerization
0.37	GO:1903937	response to acrylamide
0.37	GO:0000226	microtubule cytoskeleton organization
0.37	GO:0007420	brain development

0.62	GO:0005198	structural molecule activity
0.36	GO:0005515	protein binding
0.35	GO:0015643	toxic substance binding

0.85	GO:0005883	neurofilament
0.56	GO:0097418	neurofibrillary tangle
0.47	GO:0043209	myelin sheath
0.44	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0031965	nuclear membrane
0.42	GO:0005654	nucleoplasm
0.40	GO:0030424	axon
0.38	GO:0031594	neuromuscular junction
0.38	GO:0014069	postsynaptic density
0.36	GO:0043204	perikaryon

sp|P07199|CENPB_HUMAN
Major centromere autoantigen B
Search

CENPB

0.94	Major centromere autoantigen B

0.36	GO:0071364	cellular response to epidermal growth factor stimulus
0.36	GO:1990823	response to leukemia inhibitory factor
0.35	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0071345	cellular response to cytokine stimulus
0.35	GO:0048731	system development
0.34	GO:0006334	nucleosome assembly
0.34	GO:0017148	negative regulation of translation
0.34	GO:0048646	anatomical structure formation involved in morphogenesis
0.33	GO:0007059	chromosome segregation

0.81	GO:0003696	satellite DNA binding
0.69	GO:0003682	chromatin binding
0.39	GO:0019237	centromeric DNA binding
0.35	GO:0044547	DNA topoisomerase binding
0.35	GO:0003723	RNA binding
0.35	GO:0042162	telomeric DNA binding
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0042802	identical protein binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0005198	structural molecule activity

0.70	GO:0000775	chromosome, centromeric region
0.61	GO:0005720	nuclear heterochromatin
0.58	GO:0000794	condensed nuclear chromosome
0.58	GO:0016604	nuclear body
0.35	GO:0005730	nucleolus
0.34	GO:0036464	cytoplasmic ribonucleoprotein granule
0.34	GO:0005883	neurofilament
0.34	GO:0005938	cell cortex
0.33	GO:0070603	SWI/SNF superfamily-type complex
0.33	GO:0031982	vesicle

0.33

GO:0003887

sp|P07202|PERT_HUMAN
Thyroid peroxidase
Search

TPO

0.96	Myeloid-specific peroxidase

0.85	GO:0006590	thyroid hormone generation
0.68	GO:0006979	response to oxidative stress
0.66	GO:0098869	cellular oxidant detoxification
0.57	GO:0035162	embryonic hemopoiesis
0.51	GO:0055114	oxidation-reduction process
0.42	GO:0042446	hormone biosynthetic process
0.42	GO:0042744	hydrogen peroxide catabolic process
0.37	GO:1902170	cellular response to reactive nitrogen species
0.36	GO:0097366	response to bronchodilator
0.36	GO:0006952	defense response

0.85	GO:0004447	iodide peroxidase activity
0.63	GO:0005509	calcium ion binding
0.61	GO:0020037	heme binding

0.46	GO:0005615	extracellular space
0.44	GO:0005739	mitochondrion
0.38	GO:0009986	cell surface
0.35	GO:0005887	integral component of plasma membrane

0.85

EC:1.11.1.8

GO:0004447

sp|P07203|GPX1_HUMAN
Glutathione peroxidase 1
Search

GPX1

0.47	Glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0009609	response to symbiotic bacterium
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
0.51	GO:0051450	myoblast proliferation
0.51	GO:0010269	response to selenium ion
0.50	GO:0001659	temperature homeostasis
0.50	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.50	GO:0043403	skeletal muscle tissue regeneration

0.79	GO:0004602	glutathione peroxidase activity
0.47	GO:0017124	SH3 domain binding
0.35	GO:0003924	GTPase activity
0.35	GO:0005525	GTP binding
0.33	GO:0009055	electron transfer activity

0.50	GO:0097413	Lewy body
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.39	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.79

EC:1.11.1.9

GO:0004602

sp|P07204|TRBM_HUMAN
Thrombomodulin
Search

THBD

0.96	Thrombomodulin

0.81	GO:0030195	negative regulation of blood coagulation
0.63	GO:0007565	female pregnancy
0.60	GO:0007165	signal transduction
0.47	GO:0010165	response to X-ray
0.47	GO:0007596	blood coagulation
0.47	GO:0051591	response to cAMP
0.46	GO:0032496	response to lipopolysaccharide
0.40	GO:0051918	negative regulation of fibrinolysis
0.40	GO:0010543	regulation of platelet activation
0.39	GO:0050866	negative regulation of cell activation

0.70	GO:0005509	calcium ion binding
0.69	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0005515	protein binding
0.34	GO:0005201	extracellular matrix structural constituent
0.33	GO:0004713	protein tyrosine kinase activity
0.32	GO:0001871	pattern binding
0.32	GO:0030246	carbohydrate binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0005887	integral component of plasma membrane
0.58	GO:0009986	cell surface
0.47	GO:0016327	apicolateral plasma membrane
0.44	GO:0005774	vacuolar membrane
0.43	GO:0044421	extracellular region part

0.33

GO:0004713

sp|P07205|PGK2_HUMAN
Phosphoglycerate kinase 2
Search

PGK1

0.47	Phosphoglycerate kinase

0.70	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.48	GO:0001666	response to hypoxia
0.48	GO:0031639	plasminogen activation
0.46	GO:0036294	cellular response to decreased oxygen levels
0.46	GO:0016525	negative regulation of angiogenesis
0.45	GO:0030855	epithelial cell differentiation
0.42	GO:1903862	positive regulation of oxidative phosphorylation

0.78	GO:0004618	phosphoglycerate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0047134	protein-disulfide reductase activity
0.33	GO:0005515	protein binding

0.45	GO:0045121	membrane raft
0.44	GO:0005615	extracellular space
0.43	GO:0035686	sperm fibrous sheath
0.38	GO:1903561	extracellular vesicle
0.36	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.33	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:2.7.2.3	GO:0004618
0.78	KEGG:R01512	GO:0004618

sp|P07225|PROS_HUMAN
Vitamin K-dependent protein S
Search

PROS1

0.97	Vitamin K-dependent protein S

0.82	GO:0030195	negative regulation of blood coagulation
0.43	GO:0007596	blood coagulation
0.37	GO:0002576	platelet degranulation
0.36	GO:0030449	regulation of complement activation
0.36	GO:0017187	peptidyl-glutamic acid carboxylation
0.36	GO:0050900	leukocyte migration
0.36	GO:0050766	positive regulation of phagocytosis
0.36	GO:0001889	liver development
0.36	GO:0006465	signal peptide processing
0.35	GO:0006888	ER to Golgi vesicle-mediated transport

0.67	GO:0005509	calcium ion binding
0.35	GO:0004866	endopeptidase inhibitor activity
0.35	GO:0032403	protein complex binding

0.62	GO:0005576	extracellular region
0.37	GO:0031093	platelet alpha granule lumen
0.37	GO:0005796	Golgi lumen
0.35	GO:0000139	Golgi membrane
0.35	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P07237|PDIA1_HUMAN
Protein disulfide-isomerase
Search

P4HB

0.48	Dolichyl-diphosphooligosaccharide--protein glycotransferase

0.68	GO:0045454	cell redox homeostasis
0.57	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.57	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
0.56	GO:0046598	positive regulation of viral entry into host cell
0.53	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0071456	cellular response to hypoxia
0.42	GO:0006457	protein folding
0.41	GO:0055114	oxidation-reduction process
0.36	GO:0034378	chylomicron assembly
0.36	GO:0038155	interleukin-23-mediated signaling pathway

0.79	GO:0003756	protein disulfide isomerase activity
0.56	GO:0031545	peptidyl-proline 4-dioxygenase activity
0.54	GO:0019798	procollagen-proline dioxygenase activity
0.54	GO:0005178	integrin binding
0.52	GO:0015037	peptide disulfide oxidoreductase activity
0.51	GO:0046982	protein heterodimerization activity
0.37	GO:0019899	enzyme binding
0.34	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.69	GO:0005783	endoplasmic reticulum
0.53	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0009897	external side of plasma membrane
0.47	GO:1990204	oxidoreductase complex
0.43	GO:0044446	intracellular organelle part
0.43	GO:0042470	melanosome
0.43	GO:0043234	protein complex
0.40	GO:0043233	organelle lumen
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.79

EC:5.3.4.1

GO:0003756

sp|P07288|KLK3_HUMAN
Prostate-specific antigen
Search

0.97	Prostate-specific antigen

0.61	GO:0006508	proteolysis
0.44	GO:0002778	antibacterial peptide production
0.40	GO:0031642	negative regulation of myelination
0.39	GO:0043616	keratinocyte proliferation
0.39	GO:0048681	negative regulation of axon regeneration
0.39	GO:0022617	extracellular matrix disassembly
0.38	GO:0007613	memory
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0050807	regulation of synapse organization
0.38	GO:0050808	synapse organization

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.34	GO:0017080	sodium channel regulator activity
0.34	GO:0005515	protein binding
0.34	GO:0090729	toxin activity

0.44	GO:0005615	extracellular space
0.40	GO:0097180	serine protease inhibitor complex
0.39	GO:0005634	nucleus
0.38	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.34	GO:0012505	endomembrane system
0.34	GO:0005737	cytoplasm
0.34	GO:0046658	anchored component of plasma membrane
0.33	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P07305|H10_HUMAN
Histone H1.0
Search

H1F0

0.52	Glycine C-acetyltransferase

0.79	GO:0006334	nucleosome assembly
0.40	GO:0030261	chromosome condensation
0.37	GO:0006567	threonine catabolic process
0.37	GO:0032439	endosome localization
0.37	GO:0001919	regulation of receptor recycling
0.37	GO:0042632	cholesterol homeostasis
0.36	GO:0071230	cellular response to amino acid stimulus
0.36	GO:0007040	lysosome organization
0.36	GO:0032008	positive regulation of TOR signaling
0.36	GO:0043410	positive regulation of MAPK cascade

0.55	GO:0003677	DNA binding
0.48	GO:0003682	chromatin binding
0.38	GO:0008890	glycine C-acetyltransferase activity
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0030170	pyridoxal phosphate binding
0.35	GO:0016874	ligase activity
0.34	GO:0044877	macromolecular complex binding
0.34	GO:0003723	RNA binding
0.33	GO:0042302	structural constituent of cuticle
0.33	GO:0008270	zinc ion binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.51	GO:0000791	euchromatin
0.46	GO:0015629	actin cytoskeleton
0.45	GO:0005794	Golgi apparatus
0.44	GO:0031974	membrane-enclosed lumen
0.37	GO:0071986	Ragulator complex
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:2.3.1.29	GO:0008890
0.38	KEGG:R00371	GO:0008890

sp|P07306|ASGR1_HUMAN
Asialoglycoprotein receptor 1
Search

0.96	Asialoglycoprotein receptor 1

0.50	GO:0031668	cellular response to extracellular stimulus
0.48	GO:0055088	lipid homeostasis
0.47	GO:0031647	regulation of protein stability
0.46	GO:0009100	glycoprotein metabolic process
0.41	GO:0006897	endocytosis
0.38	GO:0030282	bone mineralization
0.38	GO:0018196	peptidyl-asparagine modification
0.36	GO:0043413	macromolecule glycosylation
0.35	GO:1901137	carbohydrate derivative biosynthetic process
0.34	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.52	GO:0042803	protein homodimerization activity
0.46	GO:0004873	asialoglycoprotein receptor activity
0.35	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005576	extracellular region

sp|P07307|ASGR2_HUMAN
Asialoglycoprotein receptor 2
Search

0.96	Asialoglycoprotein receptor 2

0.51	GO:0055088	lipid homeostasis
0.50	GO:0031647	regulation of protein stability
0.48	GO:0009100	glycoprotein metabolic process
0.46	GO:0031668	cellular response to extracellular stimulus
0.41	GO:0006897	endocytosis
0.40	GO:0030282	bone mineralization
0.38	GO:0018196	peptidyl-asparagine modification
0.36	GO:0043413	macromolecule glycosylation
0.36	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.36	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.47	GO:0042803	protein homodimerization activity
0.44	GO:0004873	asialoglycoprotein receptor activity
0.34	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.34	GO:0005886	plasma membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P07311|ACYP1_HUMAN
Acylphosphatase-1
Search

ACYP1

0.51	Acylphosphatase

0.44	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0018108	peptidyl-tyrosine phosphorylation
0.36	GO:0007131	reciprocal meiotic recombination
0.35	GO:0006298	mismatch repair
0.33	GO:0007144	female meiosis I
0.33	GO:0007130	synaptonemal complex assembly
0.33	GO:0007140	male meiotic nuclear division
0.32	GO:0010469	regulation of receptor activity
0.32	GO:0008104	protein localization

0.80	GO:0003998	acylphosphatase activity
0.45	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0030983	mismatched DNA binding
0.33	GO:0019237	centromeric DNA binding
0.32	GO:0008083	growth factor activity
0.32	GO:0003682	chromatin binding

0.36	GO:0070062	extracellular exosome
0.36	GO:0032300	mismatch repair complex
0.33	GO:0005712	chiasma
0.33	GO:0001673	male germ cell nucleus
0.33	GO:0000795	synaptonemal complex
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.80

EC:3.6.1.7

GO:0003998

sp|P07315|CRGC_HUMAN
Gamma-crystallin C
Search

0.97	Gamma-crystallin C

0.73	GO:0002088	lens development in camera-type eye
0.64	GO:0007601	visual perception
0.58	GO:0030855	epithelial cell differentiation
0.56	GO:0048593	camera-type eye morphogenesis
0.54	GO:0000904	cell morphogenesis involved in differentiation
0.44	GO:0034614	cellular response to reactive oxygen species
0.38	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.77	GO:0005212	structural constituent of eye lens
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.34	GO:0051287	NAD binding
0.34	GO:0005515	protein binding
0.34	GO:0000287	magnesium ion binding

0.55	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.35

GO:0004450

sp|P07316|CRGB_HUMAN
Gamma-crystallin B
Search

0.97	Gamma-crystallin B

0.75	GO:0002088	lens development in camera-type eye
0.61	GO:0007601	visual perception
0.60	GO:0030855	epithelial cell differentiation
0.60	GO:0048593	camera-type eye morphogenesis
0.57	GO:0000904	cell morphogenesis involved in differentiation
0.42	GO:0034614	cellular response to reactive oxygen species
0.38	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.78	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding

0.55	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P07320|CRGD_HUMAN
Gamma-crystallin D
Search

0.96	Gamma-crystallin D

0.77	GO:0002088	lens development in camera-type eye
0.62	GO:0030855	epithelial cell differentiation
0.62	GO:0007601	visual perception
0.57	GO:0048593	camera-type eye morphogenesis
0.55	GO:0000904	cell morphogenesis involved in differentiation
0.51	GO:0034614	cellular response to reactive oxygen species
0.42	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.36	GO:0005515	protein binding
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.55	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P07327|ADH1A_HUMAN
Alcohol dehydrogenase 1A
Search

0.70	Alcohol dehydrogenase E chain

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006067	ethanol metabolic process
0.48	GO:0042573	retinoic acid metabolic process
0.47	GO:0042572	retinol metabolic process
0.47	GO:0045471	response to ethanol
0.47	GO:0033574	response to testosterone
0.46	GO:0034310	primary alcohol catabolic process
0.46	GO:0032526	response to retinoic acid
0.45	GO:0030534	adult behavior
0.44	GO:0048545	response to steroid hormone

0.63	GO:0008270	zinc ion binding
0.56	GO:0004022	alcohol dehydrogenase (NAD) activity
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0004745	retinol dehydrogenase activity
0.40	GO:0035276	ethanol binding
0.39	GO:0004031	aldehyde oxidase activity
0.39	GO:0019841	retinol binding
0.38	GO:0048019	receptor antagonist activity
0.34	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.33	GO:0051287	NAD binding

0.43	GO:0005829	cytosol
0.42	GO:0005654	nucleoplasm
0.39	GO:0005739	mitochondrion
0.39	GO:0005886	plasma membrane
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.56	EC:1.1.1.1	GO:0004022
0.34	KEGG:R06983 KEGG:R07140	GO:0051903

sp|P07332|FES_HUMAN
Tyrosine-protein kinase Fes/Fps
Search

FES

0.58	Tyrosine-protein kinase transforming protein Fps

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.67	GO:0033006	regulation of mast cell activation involved in immune response
0.65	GO:0043300	regulation of leukocyte degranulation
0.64	GO:0002886	regulation of myeloid leukocyte mediated immunity
0.62	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.62	GO:0046777	protein autophosphorylation
0.61	GO:0031116	positive regulation of microtubule polymerization
0.60	GO:0045639	positive regulation of myeloid cell differentiation
0.60	GO:2000145	regulation of cell motility
0.60	GO:0032386	regulation of intracellular transport

0.77	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.62	GO:0034987	immunoglobulin receptor binding
0.55	GO:0008289	lipid binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0008017	microtubule binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005154	epidermal growth factor receptor binding
0.44	GO:0008157	protein phosphatase 1 binding

0.65	GO:0005856	cytoskeleton
0.61	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.58	GO:0005925	focal adhesion
0.53	GO:0031410	cytoplasmic vesicle
0.43	GO:0030027	lamellipodium
0.42	GO:0005829	cytosol
0.41	GO:0000790	nuclear chromatin
0.38	GO:0019028	viral capsid
0.38	GO:0005794	Golgi apparatus
0.35	GO:0005938	cell cortex

0.77

GO:0004715

sp|P07333|CSF1R_HUMAN
Macrophage colony-stimulating factor 1 receptor
Search

CSF1R

0.91	Macrophage colony stimulating factor I receptor

0.80	GO:0019221	cytokine-mediated signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.76	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.72	GO:0036005	response to macrophage colony-stimulating factor
0.72	GO:0090197	positive regulation of chemokine secretion
0.71	GO:0045217	cell-cell junction maintenance
0.69	GO:0021772	olfactory bulb development
0.69	GO:0030316	osteoclast differentiation
0.69	GO:0031529	ruffle organization
0.69	GO:2000249	regulation of actin cytoskeleton reorganization

0.84	GO:0019955	cytokine binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.67	GO:0019903	protein phosphatase binding
0.61	GO:0042803	protein homodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:1990682	CSF1-CSF1R complex
0.61	GO:0009986	cell surface
0.57	GO:0005654	nucleoplasm
0.47	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

GO:0004714

sp|P07339|CATD_HUMAN
Cathepsin D
Search

CTSD

0.84	Cathepsin D preproprotein (Predicted)

0.61	GO:0006508	proteolysis
0.43	GO:0006914	autophagy
0.41	GO:0030163	protein catabolic process
0.40	GO:0003406	retinal pigment epithelium development
0.38	GO:0061061	muscle structure development
0.38	GO:0009607	response to biotic stimulus
0.37	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.36	GO:0009605	response to external stimulus
0.36	GO:0007033	vacuole organization
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0042277	peptide binding
0.34	GO:0008234	cysteine-type peptidase activity
0.34	GO:0017171	serine hydrolase activity
0.33	GO:0005515	protein binding

0.74	GO:0005764	lysosome
0.42	GO:0042470	melanosome
0.39	GO:0005615	extracellular space
0.37	GO:0045121	membrane raft
0.37	GO:0031012	extracellular matrix
0.36	GO:1903561	extracellular vesicle
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen

0.34

GO:0008234

sp|P07355|ANXA2_HUMAN
Annexin A2
Search

ANXA2

0.60

Annexin

0.72	GO:0043086	negative regulation of catalytic activity
0.59	GO:0052362	catabolism by host of symbiont protein
0.59	GO:0044147	negative regulation of development of symbiont involved in interaction with host
0.59	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding
0.59	GO:1905599	positive regulation of low-density lipoprotein receptor activity
0.59	GO:1905581	positive regulation of low-density lipoprotein particle clearance
0.59	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport
0.59	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.58	GO:0036035	osteoclast development
0.58	GO:0052405	negative regulation by host of symbiont molecular function

0.85	GO:0004859	phospholipase inhibitor activity
0.81	GO:0005544	calcium-dependent phospholipid binding
0.71	GO:0008092	cytoskeletal protein binding
0.69	GO:0005509	calcium ion binding
0.57	GO:0098641	cadherin binding involved in cell-cell adhesion
0.56	GO:0044548	S100 protein binding
0.55	GO:0048306	calcium-dependent protein binding
0.55	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.54	GO:0002020	protease binding
0.49	GO:0042802	identical protein binding

0.58	GO:1990667	PCSK9-AnxA2 complex
0.54	GO:0005913	cell-cell adherens junction
0.54	GO:0035749	myelin sheath adaxonal region
0.54	GO:0031902	late endosome membrane
0.54	GO:0030496	midbody
0.53	GO:0005811	lipid droplet
0.53	GO:0070062	extracellular exosome
0.53	GO:0005765	lysosomal membrane
0.53	GO:0043220	Schmidt-Lanterman incisure
0.52	GO:0098857	membrane microdomain

sp|P07357|CO8A_HUMAN
Complement component C8 alpha chain
Search

C8A

0.97	Complement component 8, alpha polypeptide

0.84	GO:0006956	complement activation
0.40	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.39	GO:0019835	cytolysis
0.39	GO:0045087	innate immune response
0.37	GO:0030449	regulation of complement activation
0.34	GO:2000259	positive regulation of protein activation cascade
0.34	GO:0010954	positive regulation of protein processing
0.34	GO:0002922	positive regulation of humoral immune response
0.34	GO:0045766	positive regulation of angiogenesis
0.34	GO:0002699	positive regulation of immune effector process

0.40	GO:0001848	complement binding
0.38	GO:0032403	protein complex binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0004222	metalloendopeptidase activity
0.31	GO:0008270	zinc ion binding

0.85	GO:0005579	membrane attack complex
0.38	GO:0072562	blood microparticle
0.38	GO:0070062	extracellular exosome
0.32	GO:0005578	proteinaceous extracellular matrix

0.32

GO:0004674

sp|P07358|CO8B_HUMAN
Complement component C8 beta chain
Search

C8B

0.97	Complement component 8, beta polypeptide

0.82	GO:0006956	complement activation
0.42	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.41	GO:0045087	innate immune response
0.41	GO:0019835	cytolysis
0.36	GO:0030449	regulation of complement activation
0.36	GO:0001906	cell killing
0.36	GO:0051260	protein homooligomerization
0.32	GO:0050919	negative chemotaxis
0.31	GO:0006508	proteolysis

0.38	GO:0032403	protein complex binding
0.33	GO:0001848	complement binding
0.31	GO:0008237	metallopeptidase activity
0.31	GO:0046872	metal ion binding

0.85	GO:0005579	membrane attack complex
0.39	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.35	GO:0005829	cytosol
0.32	GO:0044218	other organism cell membrane

sp|P07359|GP1BA_HUMAN
Platelet glycoprotein Ib alpha chain
Search

GP1BA

0.96	Mutant platelet membrane glycoprotein Ib-alpha

0.60	GO:0042730	fibrinolysis
0.57	GO:0007596	blood coagulation
0.52	GO:0007155	cell adhesion
0.51	GO:0046426	negative regulation of JAK-STAT cascade
0.50	GO:0000902	cell morphogenesis
0.49	GO:0006469	negative regulation of protein kinase activity
0.48	GO:0019221	cytokine-mediated signaling pathway
0.42	GO:0045652	regulation of megakaryocyte differentiation
0.42	GO:0070493	thrombin-activated receptor signaling pathway
0.41	GO:0072376	protein activation cascade

0.50	GO:0004860	protein kinase inhibitor activity
0.42	GO:0015057	thrombin-activated receptor activity
0.38	GO:0005044	scavenger receptor activity
0.37	GO:0005515	protein binding
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0099103	channel activator activity
0.33	GO:0016301	kinase activity
0.33	GO:0015459	potassium channel regulator activity
0.33	GO:0071723	lipopeptide binding

0.60	GO:0031362	anchored component of external side of plasma membrane
0.41	GO:0070062	extracellular exosome
0.38	GO:0005887	integral component of plasma membrane
0.37	GO:0005737	cytoplasm
0.33	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex
0.33	GO:0012505	endomembrane system
0.33	GO:0098805	whole membrane
0.33	GO:0097708	intracellular vesicle
0.33	GO:0034705	potassium channel complex
0.33	GO:0042734	presynaptic membrane

0.36	EC:3.4.21	GO:0004252
0.32	KEGG:R02055	GO:0004609

sp|P07360|CO8G_HUMAN
Complement component C8 gamma chain
Search

C8G

0.96	Complement component 8, gamma polypeptide

0.46	GO:0006957	complement activation, alternative pathway
0.45	GO:0006958	complement activation, classical pathway
0.44	GO:0019835	cytolysis
0.40	GO:0030449	regulation of complement activation

0.51	GO:0036094	small molecule binding
0.44	GO:0005501	retinoid binding
0.43	GO:0001848	complement binding
0.40	GO:0032403	protein complex binding
0.35	GO:0016853	isomerase activity

0.45	GO:0005579	membrane attack complex
0.42	GO:0072562	blood microparticle
0.41	GO:0070062	extracellular exosome

0.35

GO:0016853

sp|P07384|CAN1_HUMAN
Calpain-1 catalytic subunit
Search

CAPN1

0.86	Micromolar calcium-activated neutral protease 1 large subunit

0.61	GO:0006508	proteolysis
0.54	GO:0060056	mammary gland involution
0.49	GO:0032801	receptor catabolic process
0.46	GO:0050790	regulation of catalytic activity
0.36	GO:0030154	cell differentiation
0.35	GO:2000310	regulation of NMDA receptor activity
0.35	GO:0022617	extracellular matrix disassembly
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:0016241	regulation of macroautophagy

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.70	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding
0.32	GO:0022857	transmembrane transporter activity

0.49	GO:0005764	lysosome
0.47	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.39	GO:0030141	secretory granule
0.39	GO:0097223	sperm part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031143	pseudopodium
0.34	GO:0097038	perinuclear endoplasmic reticulum

0.33

GO:0003887

sp|P07437|TBB5_HUMAN
Tubulin beta chain
Search

TUBB

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.46	GO:0070925	organelle assembly
0.45	GO:0022402	cell cycle process
0.37	GO:1902669	positive regulation of axon guidance
0.36	GO:0001764	neuron migration
0.35	GO:0042267	natural killer cell mediated cytotoxicity
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0030705	cytoskeleton-dependent intracellular transport

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0042288	MHC class I protein binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0032794	GTPase activating protein binding
0.37	GO:0019904	protein domain specific binding

0.73	GO:0005874	microtubule
0.53	GO:0005641	nuclear envelope lumen
0.50	GO:0044297	cell body
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.38	GO:0045121	membrane raft
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0035578	azurophil granule lumen
0.35	GO:0045298	tubulin complex
0.33	GO:0005829	cytosol

sp|P07438|MT1B_HUMAN
Metallothionein-1B
Search

0.75	Metallothionein-I, hippocampal

0.61	GO:0071294	cellular response to zinc ion
0.53	GO:0045926	negative regulation of growth
0.48	GO:0036018	cellular response to erythropoietin
0.47	GO:0071276	cellular response to cadmium ion
0.43	GO:0036015	response to interleukin-3
0.40	GO:0035690	cellular response to drug
0.38	GO:0006875	cellular metal ion homeostasis
0.38	GO:0071280	cellular response to copper ion
0.37	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.35	GO:0010273	detoxification of copper ion

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding
0.33	GO:0017056	structural constituent of nuclear pore

0.51	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.32	GO:0012505	endomembrane system
0.32	GO:0031967	organelle envelope
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P07451|CAH3_HUMAN
Carbonic anhydrase 3
Search

CA3

0.97	Carbonic anhydrase 3

0.71	GO:0006730	one-carbon metabolic process
0.40	GO:1901700	response to oxygen-containing compound
0.39	GO:0010033	response to organic substance
0.39	GO:0042493	response to drug
0.38	GO:0044070	regulation of anion transport
0.38	GO:2000878	positive regulation of oligopeptide transport
0.38	GO:2001148	regulation of dipeptide transmembrane transport
0.37	GO:0032849	positive regulation of cellular pH reduction
0.37	GO:1901699	cellular response to nitrogen compound
0.37	GO:0019755	one-carbon compound transport

0.78	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding
0.48	GO:0016151	nickel cation binding
0.39	GO:0004064	arylesterase activity
0.37	GO:0016791	phosphatase activity
0.32	GO:0005515	protein binding

0.48	GO:0005829	cytosol
0.42	GO:0043209	myelin sheath
0.38	GO:0045177	apical part of cell
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0043229	intracellular organelle
0.34	GO:0005886	plasma membrane
0.34	GO:0005902	microvillus
0.34	GO:0043230	extracellular organelle
0.34	GO:0030424	axon
0.33	GO:0005615	extracellular space

0.78

EC:4.2.1.1

GO:0004089

sp|P07476|INVO_HUMAN
Involucrin
Search

IVL

0.95	Involucrin

0.85	GO:0031424	keratinization
0.71	GO:0010224	response to UV-B
0.70	GO:0018149	peptide cross-linking
0.45	GO:0018199	peptidyl-glutamine modification
0.43	GO:0012501	programmed cell death
0.42	GO:0018205	peptidyl-lysine modification
0.35	GO:0043044	ATP-dependent chromatin remodeling
0.35	GO:0035329	hippo signaling
0.34	GO:0042127	regulation of cell proliferation
0.33	GO:0022900	electron transport chain

0.67	GO:0030674	protein binding, bridging
0.53	GO:0005198	structural molecule activity
0.34	GO:0017137	Rab GTPase binding
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding
0.33	GO:0009055	electron transfer activity

0.74	GO:0001533	cornified envelope
0.49	GO:0005813	centrosome
0.49	GO:0016604	nuclear body
0.48	GO:0005737	cytoplasm
0.44	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P07477|TRY1_HUMAN
Trypsin-1
Search

0.73	Cationic trypsinogen

0.61	GO:0006508	proteolysis
0.53	GO:0007586	digestion
0.39	GO:0043542	endothelial cell migration
0.38	GO:0030574	collagen catabolic process
0.37	GO:0022617	extracellular matrix disassembly
0.37	GO:0043312	neutrophil degranulation
0.36	GO:0019730	antimicrobial humoral response
0.36	GO:0007584	response to nutrient
0.36	GO:0051604	protein maturation
0.35	GO:0009235	cobalamin metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity

0.50	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.36	GO:0030141	secretory granule
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0005766	primary lysosome
0.35	GO:0097180	serine protease inhibitor complex
0.35	GO:0031983	vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P07478|TRY2_HUMAN
Trypsin-2
Search

0.73	Pancreatic anionic trypsinogen

0.61	GO:0006508	proteolysis
0.53	GO:0007586	digestion
0.40	GO:0030574	collagen catabolic process
0.39	GO:0043542	endothelial cell migration
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.37	GO:0035094	response to nicotine
0.37	GO:0022617	extracellular matrix disassembly
0.37	GO:0043312	neutrophil degranulation
0.36	GO:0019730	antimicrobial humoral response

0.69	GO:0004252	serine-type endopeptidase activity
0.40	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0004222	metalloendopeptidase activity

0.51	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.36	GO:0030141	secretory granule
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0005766	primary lysosome
0.35	GO:0031983	vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.35	GO:0097180	serine protease inhibitor complex
0.34	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P07492|GRP_HUMAN
Gastrin-releasing peptide
Search

GRP

0.97	Gastrin-releasing peptide

0.80	GO:0007218	neuropeptide signaling pathway
0.74	GO:0010469	regulation of receptor activity
0.74	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
0.72	GO:0036343	psychomotor behavior
0.68	GO:0035176	social behavior
0.56	GO:0043207	response to external biotic stimulus
0.50	GO:0090277	positive regulation of peptide hormone secretion
0.37	GO:0048565	digestive tract development

0.84

GO:0005184

neuropeptide hormone activity

0.61	GO:0005615	extracellular space
0.52	GO:0034774	secretory granule lumen

sp|P07498|CASK_HUMAN
Kappa-casein
Search

CSN3

0.92	Kappa-casein

0.58	GO:0007595	lactation
0.53	GO:0050821	protein stabilization
0.48	GO:1903496	response to 11-deoxycorticosterone
0.48	GO:1903494	response to dehydroepiandrosterone
0.46	GO:0032570	response to progesterone
0.45	GO:0032355	response to estradiol
0.43	GO:0051260	protein homooligomerization
0.34	GO:0055085	transmembrane transport

0.47	GO:0035375	zymogen binding
0.34	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.46	GO:0005796	Golgi lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P07510|ACHG_HUMAN
Acetylcholine receptor subunit gamma
Search

CHRNG

0.95	Cholinergic receptor nicotinic gamma subunit

0.80	GO:0060079	excitatory postsynaptic potential
0.65	GO:0007271	synaptic transmission, cholinergic
0.60	GO:0034220	ion transmembrane transport
0.58	GO:0035094	response to nicotine
0.57	GO:0007274	neuromuscular synaptic transmission
0.45	GO:0006812	cation transport

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.59	GO:0042166	acetylcholine binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.65	GO:0005892	acetylcholine-gated channel complex

sp|P07550|ADRB2_HUMAN
Beta-2 adrenergic receptor
Search

ADRB2

0.87	Beta-2 adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.85	GO:0006940	regulation of smooth muscle contraction
0.84	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.82	GO:0097746	regulation of blood vessel diameter
0.54	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin
0.53	GO:0007190	activation of adenylate cyclase activity
0.52	GO:1904502	regulation of lipophagy
0.51	GO:1901098	positive regulation of autophagosome maturation
0.51	GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine
0.51	GO:0061885	positive regulation of mini excitatory postsynaptic potential

0.86	GO:0004941	beta2-adrenergic receptor activity
0.54	GO:0051380	norepinephrine binding
0.49	GO:0008179	adenylate cyclase binding
0.48	GO:0015459	potassium channel regulator activity
0.48	GO:0001540	amyloid-beta binding
0.47	GO:0042803	protein homodimerization activity
0.46	GO:0051379	epinephrine binding
0.44	GO:0032403	protein complex binding
0.37	GO:0031713	B2 bradykinin receptor binding
0.36	GO:0090722	receptor-receptor interaction

0.49	GO:0043235	receptor complex
0.46	GO:0016324	apical plasma membrane
0.45	GO:0005769	early endosome
0.43	GO:0005887	integral component of plasma membrane
0.40	GO:0005634	nucleus
0.36	GO:0098805	whole membrane
0.36	GO:0032809	neuronal cell body membrane
0.35	GO:0043197	dendritic spine
0.35	GO:0042383	sarcolemma
0.35	GO:0030136	clathrin-coated vesicle

sp|P07585|PGS2_HUMAN
Decorin
Search

DCN

0.97

Decorin

0.61	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.60	GO:0051901	positive regulation of mitochondrial depolarization
0.60	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.59	GO:0090141	positive regulation of mitochondrial fission
0.58	GO:0010596	negative regulation of endothelial cell migration
0.57	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.57	GO:0016239	positive regulation of macroautophagy
0.56	GO:0016525	negative regulation of angiogenesis
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0046426	negative regulation of JAK-STAT cascade

0.83	GO:0005518	collagen binding
0.56	GO:0050840	extracellular matrix binding
0.52	GO:0005539	glycosaminoglycan binding
0.47	GO:0004860	protein kinase inhibitor activity
0.40	GO:0047485	protein N-terminus binding
0.36	GO:0098633	collagen fibril binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0003723	RNA binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0005615	extracellular space
0.43	GO:0098647	collagen beaded filament
0.39	GO:0005581	collagen trimer
0.36	GO:0005737	cytoplasm
0.34	GO:0012505	endomembrane system
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|P07602|SAP_HUMAN
Prosaposin
Search

PSAP

0.85	Proactivator polypeptide

0.79	GO:0006665	sphingolipid metabolic process
0.58	GO:0060742	epithelial cell differentiation involved in prostate gland development
0.58	GO:0060736	prostate gland growth
0.57	GO:1905572	ganglioside GM1 transport to membrane
0.56	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.55	GO:1901032	negative regulation of response to reactive oxygen species
0.55	GO:2001039	negative regulation of cellular response to drug
0.55	GO:1903205	regulation of hydrogen peroxide-induced cell death
0.54	GO:1903202	negative regulation of oxidative stress-induced cell death
0.53	GO:0019216	regulation of lipid metabolic process

0.57	GO:1905577	ganglioside GP1c binding
0.57	GO:1905575	ganglioside GM3 binding
0.57	GO:1905574	ganglioside GM2 binding
0.56	GO:1905573	ganglioside GM1 binding
0.56	GO:1905576	ganglioside GT1b binding
0.53	GO:0001664	G-protein coupled receptor binding
0.49	GO:0004565	beta-galactosidase activity
0.48	GO:0005543	phospholipid binding
0.48	GO:0042803	protein homodimerization activity
0.43	GO:0008047	enzyme activator activity

0.79	GO:0005764	lysosome
0.50	GO:0005615	extracellular space
0.48	GO:0031012	extracellular matrix
0.43	GO:0005739	mitochondrion
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005775	vacuolar lumen
0.36	GO:0030667	secretory granule membrane
0.35	GO:0098852	lytic vacuole membrane
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

0.49

EC:3.2.1.23

GO:0004565

sp|P07686|HEXB_HUMAN
Beta-hexosaminidase subunit beta
Search

HEXB

0.49	Beta-hexosaminidase subunit beta

0.60	GO:0005975	carbohydrate metabolic process
0.56	GO:0043615	astrocyte cell migration
0.56	GO:0006689	ganglioside catabolic process
0.55	GO:0007341	penetration of zona pellucida
0.55	GO:0050885	neuromuscular process controlling balance
0.54	GO:0042552	myelination
0.54	GO:0007040	lysosome organization
0.54	GO:0019915	lipid storage
0.54	GO:0008049	male courtship behavior
0.53	GO:0007605	sensory perception of sound

0.78	GO:0004563	beta-N-acetylhexosaminidase activity
0.71	GO:0102148	N-acetyl-beta-D-galactosaminidase activity
0.50	GO:0008375	acetylglucosaminyltransferase activity
0.49	GO:0046982	protein heterodimerization activity
0.49	GO:0042803	protein homodimerization activity
0.34	GO:0030246	carbohydrate binding

0.56	GO:0005766	primary lysosome
0.52	GO:0030141	secretory granule
0.51	GO:0097223	sperm part
0.48	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.37	GO:0043202	lysosomal lumen
0.36	GO:0060205	cytoplasmic vesicle lumen
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.2.1.52

GO:0004563

sp|P07711|CATL1_HUMAN
Cathepsin L1
Search

0.70	Cathepsin L

0.61	GO:0006508	proteolysis
0.49	GO:0010839	negative regulation of keratinocyte proliferation
0.49	GO:0046697	decidualization
0.49	GO:0031069	hair follicle morphogenesis
0.48	GO:2000249	regulation of actin cytoskeleton reorganization
0.46	GO:0044257	cellular protein catabolic process
0.46	GO:0097067	cellular response to thyroid hormone stimulus
0.45	GO:0030574	collagen catabolic process
0.44	GO:0002250	adaptive immune response
0.43	GO:0051604	protein maturation

0.72	GO:0008234	cysteine-type peptidase activity
0.50	GO:0042393	histone binding
0.48	GO:0097655	serpin family protein binding
0.46	GO:0001968	fibronectin binding
0.45	GO:0043394	proteoglycan binding
0.44	GO:0004175	endopeptidase activity
0.44	GO:0005518	collagen binding
0.43	GO:0004180	carboxypeptidase activity
0.41	GO:0030984	kininogen binding
0.38	GO:0042277	peptide binding

0.53	GO:0005764	lysosome
0.50	GO:0005615	extracellular space
0.44	GO:0031410	cytoplasmic vesicle
0.44	GO:0005730	nucleolus
0.39	GO:0043204	perikaryon
0.39	GO:0005902	microvillus
0.39	GO:0009897	external side of plasma membrane
0.39	GO:0045177	apical part of cell
0.38	GO:0043005	neuron projection
0.37	GO:0012505	endomembrane system

0.72

GO:0008234

sp|P07737|PROF1_HUMAN
Profilin-1
Search

0.67

Profilin

0.73	GO:0030036	actin cytoskeleton organization
0.71	GO:0030833	regulation of actin filament polymerization
0.55	GO:0032231	regulation of actin filament bundle assembly
0.55	GO:1900027	regulation of ruffle assembly
0.53	GO:0110020	regulation of actomyosin structure organization
0.53	GO:1902905	positive regulation of supramolecular fiber organization
0.52	GO:0010632	regulation of epithelial cell migration
0.52	GO:0051495	positive regulation of cytoskeleton organization
0.52	GO:0044089	positive regulation of cellular component biogenesis
0.52	GO:0032272	negative regulation of protein polymerization

0.74	GO:0003779	actin binding
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.48	GO:0070064	proline-rich region binding
0.45	GO:0045296	cadherin binding
0.45	GO:0000774	adenyl-nucleotide exchange factor activity
0.44	GO:0017048	Rho GTPase binding
0.39	GO:0016887	ATPase activity
0.36	GO:0005102	receptor binding
0.33	GO:0003723	RNA binding

0.47	GO:0043195	terminal bouton
0.44	GO:0005938	cell cortex
0.43	GO:0005615	extracellular space
0.40	GO:0005634	nucleus
0.38	GO:0005856	cytoskeleton
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005925	focal adhesion
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.39

GO:0016887

sp|P07738|PMGE_HUMAN
Bisphosphoglycerate mutase
Search

BPGM

0.47	Bisphosphoglycerate mutase

0.70	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.50	GO:0019319	hexose biosynthetic process
0.49	GO:0006006	glucose metabolic process
0.49	GO:0043456	regulation of pentose-phosphate shunt
0.39	GO:0048821	erythrocyte development
0.35	GO:0007585	respiratory gaseous exchange
0.33	GO:0044282	small molecule catabolic process

0.80	GO:0004082	bisphosphoglycerate mutase activity
0.77	GO:0004619	phosphoglycerate mutase activity
0.34	GO:0016787	hydrolase activity

0.44	GO:0005829	cytosol
0.40	GO:0005758	mitochondrial intermembrane space
0.37	GO:0070062	extracellular exosome
0.34	GO:0005861	troponin complex
0.30	GO:0016020	membrane

0.80

EC:5.4.2.4

GO:0004082

sp|P07741|APT_HUMAN
Adenine phosphoribosyltransferase
Search

APRT

0.47	Adenine phosphoribosyltransferase

0.77	GO:0006168	adenine salvage
0.66	GO:0009116	nucleoside metabolic process
0.57	GO:0044209	AMP salvage
0.56	GO:0007625	grooming behavior
0.54	GO:1901659	glycosyl compound biosynthetic process
0.39	GO:0007595	lactation
0.38	GO:0032869	cellular response to insulin stimulus
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0006298	mismatch repair

0.77	GO:0003999	adenine phosphoribosyltransferase activity
0.58	GO:0002055	adenine binding
0.51	GO:0016208	AMP binding
0.34	GO:0008484	sulfuric ester hydrolase activity
0.33	GO:0030983	mismatched DNA binding
0.32	GO:0003723	RNA binding
0.32	GO:0005524	ATP binding

0.48	GO:0005737	cytoplasm
0.47	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.77

EC:2.4.2.7

GO:0003999

sp|P07766|CD3E_HUMAN
T-cell surface glycoprotein CD3 epsilon chain
Search

CD3E

0.97	T-cell surface glycoprotein CD3 epsilon chain

0.69	GO:0007166	cell surface receptor signaling pathway
0.65	GO:0002913	positive regulation of lymphocyte anergy
0.64	GO:0002666	positive regulation of T cell tolerance induction
0.64	GO:0002667	regulation of T cell anergy
0.63	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.63	GO:0045060	negative thymic T cell selection
0.63	GO:0046641	positive regulation of alpha-beta T cell proliferation
0.63	GO:0032753	positive regulation of interleukin-4 production
0.62	GO:0031295	T cell costimulation
0.62	GO:0045879	negative regulation of smoothened signaling pathway

0.68	GO:0004888	transmembrane signaling receptor activity
0.58	GO:0017124	SH3 domain binding
0.55	GO:0042803	protein homodimerization activity
0.55	GO:0046982	protein heterodimerization activity
0.41	GO:0042608	T cell receptor binding
0.38	GO:0030159	receptor signaling complex scaffold activity
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0019901	protein kinase binding

0.64	GO:0042105	alpha-beta T cell receptor complex
0.61	GO:0001772	immunological synapse
0.60	GO:0043197	dendritic spine
0.59	GO:0009897	external side of plasma membrane
0.58	GO:0044297	cell body
0.56	GO:0005911	cell-cell junction
0.35	GO:0005887	integral component of plasma membrane

sp|P07814|SYEP_HUMAN
Bifunctional glutamate/proline--tRNA ligase
Search

EPRS

0.83	Bifunctional aminoacyl-tRNA synthetase

0.77	GO:0006433	prolyl-tRNA aminoacylation
0.75	GO:0006424	glutamyl-tRNA aminoacylation
0.67	GO:0071346	cellular response to interferon-gamma
0.61	GO:0017148	negative regulation of translation

0.77	GO:0004827	proline-tRNA ligase activity
0.76	GO:0004818	glutamate-tRNA ligase activity
0.70	GO:0035613	RNA stem-loop binding
0.60	GO:0042803	protein homodimerization activity
0.59	GO:0051020	GTPase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008270	zinc ion binding

0.72	GO:0097452	GAIT complex
0.71	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.56	GO:0005829	cytosol
0.51	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.77

EC:6.1.1.15

GO:0004827

sp|P07858|CATB_HUMAN
Cathepsin B
Search

CTSB

0.84	Cathepsin B

0.66	GO:0050790	regulation of catalytic activity
0.59	GO:0006508	proteolysis
0.57	GO:0097067	cellular response to thyroid hormone stimulus
0.56	GO:0030574	collagen catabolic process
0.54	GO:0046697	decidualization
0.53	GO:0060429	epithelium development
0.50	GO:0044257	cellular protein catabolic process
0.49	GO:0030154	cell differentiation
0.46	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.46	GO:0044409	entry into host

0.72	GO:0004197	cysteine-type endopeptidase activity
0.56	GO:0043394	proteoglycan binding
0.54	GO:0005518	collagen binding
0.35	GO:0030984	kininogen binding
0.35	GO:0043621	protein self-association
0.34	GO:0042277	peptide binding
0.34	GO:0004252	serine-type endopeptidase activity

0.54	GO:0005764	lysosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005615	extracellular space
0.51	GO:0005730	nucleolus
0.43	GO:0005739	mitochondrion
0.42	GO:0042470	melanosome
0.36	GO:1903561	extracellular vesicle
0.36	GO:0031904	endosome lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen

0.72

EC:3.4.22

GO:0004197

sp|P07864|LDHC_HUMAN
L-lactate dehydrogenase C chain
Search

0.53	L-lactate dehydrogenase C chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0030317	flagellated sperm motility
0.46	GO:1901617	organic hydroxy compound biosynthetic process
0.45	GO:0006754	ATP biosynthetic process
0.42	GO:0016053	organic acid biosynthetic process
0.35	GO:0021762	substantia nigra development
0.35	GO:0051591	response to cAMP
0.35	GO:0043627	response to estrogen

0.81	GO:0004459	L-lactate dehydrogenase activity
0.37	GO:0045296	cadherin binding
0.36	GO:0042802	identical protein binding
0.34	GO:0019900	kinase binding
0.33	GO:0051287	NAD binding
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.49	GO:0031514	motile cilium
0.48	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0043209	myelin sheath
0.35	GO:0045121	membrane raft
0.35	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P07900|HS90A_HUMAN
Heat shock protein HSP 90-alpha
Search

HSP90AA1

0.87	Epididymis luminal secretory protein 52

0.69	GO:0006457	protein folding
0.67	GO:0009409	response to cold
0.63	GO:0009408	response to heat
0.62	GO:0046677	response to antibiotic
0.52	GO:1905323	telomerase holoenzyme complex assembly
0.51	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.50	GO:0051973	positive regulation of telomerase activity
0.50	GO:0007004	telomere maintenance via telomerase
0.49	GO:0045040	protein import into mitochondrial outer membrane
0.48	GO:0051131	chaperone-mediated protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0030235	nitric-oxide synthase regulator activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0030911	TPR domain binding
0.51	GO:0070182	DNA polymerase binding
0.50	GO:0097110	scaffold protein binding
0.50	GO:0097718	disordered domain specific binding

0.53	GO:0005634	nucleus
0.48	GO:0032587	ruffle membrane
0.47	GO:0043209	myelin sheath
0.45	GO:0042470	melanosome
0.44	GO:0005829	cytosol
0.40	GO:0043234	protein complex
0.39	GO:0097226	sperm mitochondrial sheath
0.39	GO:0030018	Z disc
0.39	GO:0097524	sperm plasma membrane
0.38	GO:0043025	neuronal cell body

0.42

GO:0016887

sp|P07902|GALT_HUMAN
Galactose-1-phosphate uridylyltransferase
Search

GALT

0.58	Galactose-1-phosphate uridylyltransferase

0.82	GO:0033499	galactose catabolic process via UDP-galactose
0.51	GO:0006011	UDP-glucose metabolic process
0.42	GO:0009227	nucleotide-sugar catabolic process
0.40	GO:0019221	cytokine-mediated signaling pathway
0.39	GO:0061623	glycolytic process from galactose

0.81	GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity
0.63	GO:0008270	zinc ion binding
0.40	GO:0004896	cytokine receptor activity
0.35	GO:0005536	glucose binding
0.35	GO:0005534	galactose binding
0.34	GO:0005515	protein binding
0.32	GO:0046316	gluconokinase activity

0.48	GO:0005794	Golgi apparatus
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.81	EC:2.7.7.12	GO:0008108
0.81	KEGG:R00955	GO:0008108

sp|P07910|HNRPC_HUMAN
Heterogeneous nuclear ribonucleoproteins C1/C2
Search

HNRNPC

0.96	Heterogeneous nuclear ribonucleoprotein C

0.43	GO:0070935	3'-UTR-mediated mRNA stabilization
0.43	GO:0032211	negative regulation of telomere maintenance via telomerase
0.41	GO:0000398	mRNA splicing, via spliceosome
0.37	GO:0001649	osteoblast differentiation
0.36	GO:0043044	ATP-dependent chromatin remodeling
0.36	GO:0090367	negative regulation of mRNA modification
0.34	GO:0043086	negative regulation of catalytic activity
0.33	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.59	GO:0003723	RNA binding
0.40	GO:0042802	identical protein binding
0.37	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0031492	nucleosomal DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:1990827	deaminase binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0004857	enzyme inhibitor activity
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0004984	olfactory receptor activity

0.57	GO:0019013	viral nucleocapsid
0.51	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0045120	pronucleus
0.40	GO:0005654	nucleoplasm
0.40	GO:0015629	actin cytoskeleton
0.38	GO:0005829	cytosol
0.38	GO:0005576	extracellular region
0.37	GO:1902494	catalytic complex
0.37	GO:0043234	protein complex
0.35	GO:0000790	nuclear chromatin

sp|P07911|UROM_HUMAN
Uromodulin
Search

UMOD

0.93	Pancreatic zymogen granule membrane protein GP-2

0.62	GO:0072233	metanephric thick ascending limb development
0.61	GO:0072221	metanephric distal convoluted tubule development
0.61	GO:0072021	ascending thin limb development
0.61	GO:0072236	metanephric loop of Henle development
0.58	GO:0007588	excretion
0.58	GO:0007159	leukocyte cell-cell adhesion
0.57	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.57	GO:1990266	neutrophil migration
0.55	GO:2000021	regulation of ion homeostasis
0.50	GO:0048878	chemical homeostasis

0.62	GO:0005509	calcium ion binding
0.60	GO:0019864	IgG binding
0.37	GO:0005201	extracellular matrix structural constituent
0.36	GO:0003823	antigen binding
0.35	GO:0016504	peptidase activator activity
0.34	GO:0051537	2 iron, 2 sulfur cluster binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.64	GO:0005576	extracellular region
0.57	GO:0016324	apical plasma membrane
0.56	GO:0016323	basolateral plasma membrane
0.56	GO:0031225	anchored component of membrane
0.55	GO:0000922	spindle pole
0.53	GO:0005929	cilium
0.44	GO:0031253	cell projection membrane
0.41	GO:0098588	bounding membrane of organelle
0.38	GO:0031982	vesicle
0.37	GO:0005796	Golgi lumen

sp|P07919|QCR6_HUMAN
Cytochrome b-c1 complex subunit 6, mitochondrial
Search

0.82	Ubiquinol-cytochrome c reductase hinge protein (Fragment)

0.74	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.42	GO:0009060	aerobic respiration
0.37	GO:0051291	protein heterooligomerization
0.35	GO:0032259	methylation
0.33	GO:0016477	cell migration
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0006457	protein folding
0.32	GO:0006468	protein phosphorylation

0.74	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.61	GO:0009055	electron transfer activity
0.36	GO:0005515	protein binding
0.35	GO:0017064	fatty acid amide hydrolase activity
0.35	GO:0044877	macromolecular complex binding
0.35	GO:0008168	methyltransferase activity
0.34	GO:0003723	RNA binding
0.34	GO:0004040	amidase activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0005509	calcium ion binding

0.60	GO:0005739	mitochondrion
0.57	GO:0070469	respiratory chain
0.56	GO:0019866	organelle inner membrane
0.44	GO:0070069	cytochrome complex
0.44	GO:1990204	oxidoreductase complex
0.41	GO:0098796	membrane protein complex
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0016681

sp|P07942|LAMB1_HUMAN
Laminin subunit beta-1
Search

LAMB1B

0.93	Laminin, beta 1a

0.88	GO:0055016	hypochord development
0.86	GO:0014028	notochord formation
0.86	GO:0007634	optokinetic behavior
0.86	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.86	GO:0031101	fin regeneration
0.86	GO:0050908	detection of light stimulus involved in visual perception
0.85	GO:0031290	retinal ganglion cell axon guidance
0.85	GO:0048854	brain morphogenesis
0.85	GO:1902017	regulation of cilium assembly
0.84	GO:0061053	somite development

sp|P07947|YES_HUMAN
Tyrosine-protein kinase Yes
Search

YES1

0.58	Tyrosine-protein kinase Yes

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.50	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.50	GO:0046777	protein autophosphorylation
0.49	GO:0071300	cellular response to retinoic acid
0.48	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.48	GO:0071560	cellular response to transforming growth factor beta stimulus
0.48	GO:0015758	glucose transport
0.46	GO:0045087	innate immune response
0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.46	GO:0016477	cell migration

0.81	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0001784	phosphotyrosine residue binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0044325	ion channel binding
0.47	GO:0019899	enzyme binding
0.45	GO:0005102	receptor binding
0.33	GO:0032403	protein complex binding

0.48	GO:0005884	actin filament
0.47	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005815	microtubule organizing center
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0016235	aggresome
0.34	GO:0032587	ruffle membrane

0.81

GO:0004715

sp|P07948|LYN_HUMAN
Tyrosine-protein kinase Lyn
Search

LYN

0.59	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0070666	regulation of mast cell proliferation
0.60	GO:2000670	positive regulation of dendritic cell apoptotic process
0.59	GO:0002513	tolerance induction to self antigen
0.59	GO:0002774	Fc receptor mediated inhibitory signaling pathway
0.58	GO:0002431	Fc receptor mediated stimulatory signaling pathway
0.58	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway
0.58	GO:0002576	platelet degranulation
0.58	GO:0002688	regulation of leukocyte chemotaxis
0.58	GO:1905247	positive regulation of aspartic-type peptidase activity

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.59	GO:0140031	phosphorylation-dependent protein binding
0.55	GO:0046875	ephrin receptor binding
0.55	GO:0044325	ion channel binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.52	GO:0017124	SH3 domain binding
0.50	GO:0032403	protein complex binding

0.52	GO:0045121	membrane raft
0.52	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005794	Golgi apparatus
0.46	GO:0005634	nucleus
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0034666	integrin alpha2-beta1 complex
0.35	GO:0042629	mast cell granule
0.35	GO:0014069	postsynaptic density

0.80

GO:0004715

sp|P07949|RET_HUMAN
Proto-oncogene tyrosine-protein kinase receptor Ret
Search

RET

0.94	Proto-oncogene tyrosine-protein kinase receptor Ret

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.74	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.63	GO:0061146	Peyer's patch morphogenesis
0.63	GO:0048484	enteric nervous system development
0.63	GO:0035799	ureter maturation
0.63	GO:0072300	positive regulation of metanephric glomerulus development
0.62	GO:0001755	neural crest cell migration
0.61	GO:0007158	neuron cell-cell adhesion
0.61	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.60	GO:0048265	response to pain

0.76	GO:0004713	protein tyrosine kinase activity
0.67	GO:0005509	calcium ion binding
0.67	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005515	protein binding
0.38	GO:0003777	microtubule motor activity
0.37	GO:0008376	acetylgalactosaminyltransferase activity

0.68	GO:0098857	membrane microdomain
0.55	GO:0043235	receptor complex
0.54	GO:0010008	endosome membrane
0.50	GO:0005829	cytosol
0.49	GO:0005886	plasma membrane
0.46	GO:0098796	membrane protein complex
0.44	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0043025	neuronal cell body
0.40	GO:0030425	dendrite
0.40	GO:0005769	early endosome

0.76

GO:0004713

sp|P07951|TPM2_HUMAN
Tropomyosin beta chain
Search

TPM2

0.83	Tropomyosin beta chain

0.67	GO:0043462	regulation of ATPase activity
0.66	GO:0006936	muscle contraction
0.61	GO:0007015	actin filament organization
0.41	GO:0033275	actin-myosin filament sliding
0.39	GO:0007016	cytoskeletal anchoring at plasma membrane
0.37	GO:0007155	cell adhesion

0.70	GO:0003779	actin binding
0.70	GO:0008307	structural constituent of muscle
0.63	GO:0032403	protein complex binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.41	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding

0.73	GO:0005862	muscle thin filament tropomyosin
0.68	GO:0005884	actin filament
0.51	GO:0097517	contractile actin filament bundle
0.51	GO:0042641	actomyosin
0.48	GO:0002102	podosome
0.46	GO:0030863	cortical cytoskeleton
0.38	GO:0001726	ruffle
0.38	GO:0005925	focal adhesion
0.37	GO:0005829	cytosol

sp|P07954|FUMH_HUMAN
Fumarate hydratase, mitochondrial
Search

0.54	Fumarate hydratase, mitochondrial

0.78	GO:0006106	fumarate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.53	GO:0048873	homeostasis of number of cells within a tissue
0.46	GO:0006108	malate metabolic process
0.34	GO:0022900	electron transport chain
0.34	GO:0007034	vacuolar transport

0.79	GO:0004333	fumarate hydratase activity
0.37	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.35	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0005515	protein binding

0.77	GO:0045239	tricarboxylic acid cycle enzyme complex
0.45	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0044446	intracellular organelle part
0.34	GO:0031090	organelle membrane
0.34	GO:0031975	envelope
0.33	GO:0031974	membrane-enclosed lumen

0.79	EC:4.2.1.2	GO:0004333
0.79	KEGG:R01082	GO:0004333

sp|P07988|PSPB_HUMAN
Pulmonary surfactant-associated protein B
Search

SFTPB

0.96	Pulmonary surfactant-associated protein B

0.71	GO:0006665	sphingolipid metabolic process
0.59	GO:0007585	respiratory gaseous exchange
0.52	GO:0009887	animal organ morphogenesis
0.50	GO:0043085	positive regulation of catalytic activity
0.43	GO:0050828	regulation of liquid surface tension
0.43	GO:0033189	response to vitamin A
0.42	GO:0071732	cellular response to nitric oxide
0.42	GO:0055093	response to hyperoxia
0.42	GO:0070741	response to interleukin-6
0.42	GO:0070849	response to epidermal growth factor

0.54	GO:0001664	G-protein coupled receptor binding
0.51	GO:0008047	enzyme activator activity

0.71	GO:0005764	lysosome
0.59	GO:0097208	alveolar lamellar body
0.57	GO:0005771	multivesicular body
0.52	GO:0005615	extracellular space
0.46	GO:0031906	late endosome lumen
0.43	GO:0045334	clathrin-coated endocytic vesicle
0.40	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0005654	nucleoplasm

sp|P07992|ERCC1_HUMAN
DNA excision repair protein ERCC-1
Search

ERCC1

0.89	Excision repair cross-complementing rodent repair deficiency complementation group 1

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.58	GO:0006312	mitotic recombination
0.57	GO:1904431	positive regulation of t-circle formation
0.57	GO:1905765	negative regulation of protection from non-homologous end joining at telomere
0.57	GO:0090737	telomere maintenance via telomere trimming
0.57	GO:0001325	formation of extrachromosomal circular DNA
0.56	GO:0009650	UV protection
0.55	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.55	GO:0035166	post-embryonic hemopoiesis

0.73	GO:0003684	damaged DNA binding
0.66	GO:0004519	endonuclease activity
0.56	GO:0001094	TFIID-class transcription factor binding
0.53	GO:0008022	protein C-terminus binding
0.52	GO:0003697	single-stranded DNA binding
0.50	GO:0004536	deoxyribonuclease activity
0.50	GO:0019904	protein domain specific binding
0.38	GO:0031593	polyubiquitin modification-dependent protein binding
0.35	GO:0017025	TBP-class protein binding
0.34	GO:0004792	thiosulfate sulfurtransferase activity

0.61	GO:0005634	nucleus
0.53	GO:1990391	DNA repair complex
0.51	GO:0000781	chromosome, telomeric region
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0005667	transcription factor complex
0.48	GO:0043233	organelle lumen
0.47	GO:0005829	cytosol
0.38	GO:0035861	site of double-strand break
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.34	EC:2.8.1.1	GO:0004792
0.34	KEGG:R01931	GO:0004792

sp|P07996|TSP1_HUMAN
Thrombospondin-1
Search

THBS1

0.93	Thrombospondin-1

0.84	GO:0016525	negative regulation of angiogenesis
0.81	GO:0030198	extracellular matrix organization
0.80	GO:0006954	inflammatory response
0.72	GO:0007155	cell adhesion
0.64	GO:0002605	negative regulation of dendritic cell antigen processing and presentation
0.63	GO:0010754	negative regulation of cGMP-mediated signaling
0.63	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.62	GO:2001027	negative regulation of endothelial cell chemotaxis
0.62	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.62	GO:0010757	negative regulation of plasminogen activation

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0008201	heparin binding
0.70	GO:0005509	calcium ion binding
0.63	GO:0070052	collagen V binding
0.63	GO:0070051	fibrinogen binding
0.61	GO:0030169	low-density lipoprotein particle binding
0.60	GO:0001968	fibronectin binding
0.60	GO:0017134	fibroblast growth factor binding
0.60	GO:0001786	phosphatidylserine binding
0.58	GO:0005178	integrin binding

0.74	GO:0031012	extracellular matrix
0.73	GO:0005615	extracellular space
0.60	GO:0031091	platelet alpha granule
0.56	GO:0009897	external side of plasma membrane
0.45	GO:0043234	protein complex
0.44	GO:0016529	sarcoplasmic reticulum
0.40	GO:1903561	extracellular vesicle
0.36	GO:0034774	secretory granule lumen
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|P07998|RNAS1_HUMAN
Ribonuclease pancreatic
Search

RNASE1

0.92	Pancreatic ribonuclease subtype Nb

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.43	GO:0016070	RNA metabolic process
0.34	GO:0051607	defense response to virus

0.66	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.50	GO:0004540	ribonuclease activity
0.33	GO:0005515	protein binding

0.45	GO:0005576	extracellular region
0.34	GO:0031982	vesicle
0.30	GO:0044425	membrane part

sp|P08034|CXB1_HUMAN
Gap junction beta-1 protein
Search

GJB1

0.65	Gap junction beta-1 protein (Fragment)

0.60	GO:0007154	cell communication
0.44	GO:0016264	gap junction assembly
0.40	GO:1905867	epididymis development
0.39	GO:0015868	purine ribonucleotide transport
0.37	GO:0023052	signaling
0.37	GO:0055085	transmembrane transport
0.36	GO:0051259	protein oligomerization
0.34	GO:0007399	nervous system development
0.34	GO:0007605	sensory perception of sound

0.52	GO:0042802	identical protein binding
0.48	GO:0046983	protein dimerization activity
0.46	GO:0005243	gap junction channel activity

0.83	GO:0005922	connexin complex
0.39	GO:0005737	cytoplasm
0.38	GO:0016328	lateral plasma membrane
0.36	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|P08047|SP1_HUMAN
Transcription factor Sp1
Search

SP1

0.96	Transcription factor Sp1

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.67	GO:1904828	positive regulation of hydrogen sulfide biosynthetic process
0.64	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.63	GO:0043923	positive regulation by host of viral transcription
0.61	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.60	GO:0045766	positive regulation of angiogenesis
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:0060136	embryonic process involved in female pregnancy
0.40	GO:0048511	rhythmic process

0.63	GO:0071837	HMG box domain binding
0.61	GO:0070491	repressing transcription factor binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0042826	histone deacetylase binding
0.59	GO:0008022	protein C-terminus binding
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0042803	protein homodimerization activity
0.42	GO:0043425	bHLH transcription factor binding
0.41	GO:0001046	core promoter sequence-specific DNA binding
0.41	GO:0001085	RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.58	GO:0017053	transcriptional repressor complex
0.53	GO:0000785	chromatin
0.51	GO:0031974	membrane-enclosed lumen
0.37	GO:0032993	protein-DNA complex
0.34	GO:0005737	cytoplasm

sp|P08048|ZFY_HUMAN
Zinc finger Y-chromosomal protein
Search

ZFX

0.67	Zinc finger protein Y-linked

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.50	GO:0060746	parental behavior
0.48	GO:0001541	ovarian follicle development
0.48	GO:0035264	multicellular organism growth
0.48	GO:0048599	oocyte development
0.47	GO:0009566	fertilization
0.46	GO:0007283	spermatogenesis
0.46	GO:0009791	post-embryonic development

0.53	GO:0003677	DNA binding
0.52	GO:0046872	metal ion binding
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part

sp|P08069|IGF1R_HUMAN
Insulin-like growth factor 1 receptor
Search

IGF1R

0.67	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.72	GO:0046777	protein autophosphorylation
0.58	GO:0051389	inactivation of MAPKK activity
0.57	GO:0097242	amyloid-beta clearance
0.56	GO:1904646	cellular response to amyloid-beta
0.54	GO:0045740	positive regulation of DNA replication
0.53	GO:0046328	regulation of JNK cascade
0.52	GO:0043066	negative regulation of apoptotic process
0.52	GO:0051262	protein tetramerization

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.79	GO:0043560	insulin receptor substrate binding
0.78	GO:0043548	phosphatidylinositol 3-kinase binding
0.63	GO:0005520	insulin-like growth factor binding
0.57	GO:0043559	insulin binding
0.55	GO:0005158	insulin receptor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding

0.57	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.51	GO:0043235	receptor complex
0.41	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0030315	T-tubule
0.35	GO:0005901	caveola
0.35	GO:0043025	neuronal cell body
0.35	GO:0030424	axon
0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005737	cytoplasm

0.80

GO:0004714

sp|P08100|OPSD_HUMAN
Rhodopsin
Search

RHO

0.57

Rhodopsin

0.79	GO:0007602	phototransduction
0.75	GO:0007601	visual perception
0.71	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0016037	light absorption
0.58	GO:0071482	cellular response to light stimulus
0.56	GO:0045494	photoreceptor cell maintenance
0.54	GO:0060041	retina development in camera-type eye
0.51	GO:0009584	detection of visible light
0.45	GO:0006468	protein phosphorylation

0.75	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.53	GO:0005502	11-cis retinal binding
0.41	GO:0042802	identical protein binding
0.39	GO:0046983	protein dimerization activity
0.39	GO:0046872	metal ion binding
0.37	GO:0030507	spectrin binding
0.35	GO:0002046	opsin binding
0.35	GO:1990763	arrestin family protein binding
0.35	GO:0001965	G-protein alpha-subunit binding

0.66	GO:0060342	photoreceptor inner segment membrane
0.64	GO:0097381	photoreceptor disc membrane
0.64	GO:0042622	photoreceptor outer segment membrane
0.51	GO:0005911	cell-cell junction
0.49	GO:0005794	Golgi apparatus
0.36	GO:0031984	organelle subcompartment
0.35	GO:0097648	G-protein coupled receptor complex
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0030660	Golgi-associated vesicle membrane
0.34	GO:0000786	nucleosome

sp|P08118|MSMB_HUMAN
Beta-microseminoprotein
Search

MSMB

0.87	Beta-microseminoprotein A1

0.37

GO:0005515

protein binding

0.66	GO:0005576	extracellular region
0.36	GO:0005634	nucleus

sp|P08123|CO1A2_HUMAN
Collagen alpha-2(I) chain
Search

COL1A2

0.83	Procollagen type I alpha 2 chain

0.66	GO:0009612	response to mechanical stimulus
0.40	GO:0043589	skin morphogenesis
0.39	GO:0030199	collagen fibril organization
0.39	GO:0007266	Rho protein signal transduction
0.39	GO:0007179	transforming growth factor beta receptor signaling pathway
0.39	GO:0008217	regulation of blood pressure
0.38	GO:0001501	skeletal system development
0.38	GO:0001568	blood vessel development

0.82	GO:0005201	extracellular matrix structural constituent
0.40	GO:0048407	platelet-derived growth factor binding
0.39	GO:0002020	protease binding
0.38	GO:0030674	protein binding, bridging
0.37	GO:0042802	identical protein binding

0.63	GO:0005581	collagen trimer
0.40	GO:0098643	banded collagen fibril
0.37	GO:0005615	extracellular space
0.37	GO:0005783	endoplasmic reticulum

sp|P08133|ANXA6_HUMAN
Annexin A6
Search

ANXA6

0.49

Annexin

0.57	GO:0051560	mitochondrial calcium ion homeostasis
0.54	GO:0006937	regulation of muscle contraction
0.54	GO:0097190	apoptotic signaling pathway
0.53	GO:0006816	calcium ion transport
0.52	GO:0051260	protein homooligomerization
0.45	GO:0034220	ion transmembrane transport
0.39	GO:0051283	negative regulation of sequestering of calcium ion
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0001778	plasma membrane repair
0.37	GO:0046903	secretion

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.56	GO:0048306	calcium-dependent protein binding
0.55	GO:0015485	cholesterol binding
0.52	GO:0015276	ligand-gated ion channel activity
0.51	GO:0042803	protein homodimerization activity
0.47	GO:0032550	purine ribonucleoside binding
0.46	GO:0019001	guanyl nucleotide binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0031902	late endosome membrane
0.54	GO:0005765	lysosomal membrane
0.53	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005739	mitochondrion
0.43	GO:0042470	melanosome
0.42	GO:0005925	focal adhesion
0.42	GO:0070062	extracellular exosome
0.39	GO:0014704	intercalated disc
0.39	GO:0042383	sarcolemma
0.38	GO:0016324	apical plasma membrane

sp|P08134|RHOC_HUMAN
Rho-related GTP-binding protein RhoC
Search

RHOC

0.97	Rho-related GTP-binding protein RhoC

0.77	GO:0007264	small GTPase mediated signal transduction
0.71	GO:1902766	skeletal muscle satellite cell migration
0.69	GO:0090505	epiboly involved in wound healing
0.57	GO:0032464	positive regulation of protein homooligomerization
0.55	GO:0043297	apical junction assembly
0.55	GO:0060193	positive regulation of lipase activity
0.54	GO:0061640	cytoskeleton-dependent cytokinesis
0.50	GO:1903047	mitotic cell cycle process
0.41	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission
0.41	GO:0030241	skeletal muscle myosin thick filament assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0032794	GTPase activating protein binding
0.38	GO:0019901	protein kinase binding
0.35	GO:0004871	signal transducer activity
0.35	GO:0004721	phosphoprotein phosphatase activity

0.56	GO:0097610	cell surface furrow
0.55	GO:0032420	stereocilium
0.54	GO:0032155	cell division site part
0.45	GO:0005622	intracellular
0.42	GO:0071944	cell periphery
0.41	GO:0043227	membrane-bounded organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

EC:3.1.3.16

GO:0004721

sp|P08138|TNR16_HUMAN
Tumor necrosis factor receptor superfamily member 16
Search

NGFR

0.95	Nerve growth factor receptor b

0.75	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.73	GO:1904646	cellular response to amyloid-beta
0.73	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.72	GO:0051402	neuron apoptotic process
0.70	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.70	GO:0007266	Rho protein signal transduction
0.69	GO:1900182	positive regulation of protein localization to nucleus
0.54	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.53	GO:0010977	negative regulation of neuron projection development
0.52	GO:0032496	response to lipopolysaccharide

0.74	GO:0005035	death receptor activity
0.71	GO:0015026	coreceptor activity
0.66	GO:0031625	ubiquitin protein ligase binding
0.66	GO:0005516	calmodulin binding
0.56	GO:0048406	nerve growth factor binding

0.50	GO:0043005	neuron projection
0.49	GO:0005886	plasma membrane
0.43	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P08151|GLI1_HUMAN
Zinc finger protein GLI1
Search

GLI1

0.88	GLI family zinc finger 1

0.82	GO:0007224	smoothened signaling pathway
0.82	GO:0060032	notochord regression
0.82	GO:0007418	ventral midline development
0.80	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
0.79	GO:0021983	pituitary gland development
0.78	GO:2000345	regulation of hepatocyte proliferation
0.78	GO:0045880	positive regulation of smoothened signaling pathway
0.77	GO:0097421	liver regeneration
0.77	GO:0022037	metencephalon development
0.76	GO:0009954	proximal/distal pattern formation

0.73	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.70	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.68	GO:0003682	chromatin binding
0.65	GO:0008017	microtubule binding
0.41	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0008134	transcription factor binding
0.38	GO:0008270	zinc ion binding

0.79	GO:0097542	ciliary tip
0.72	GO:0005930	axoneme
0.62	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.48	GO:0035301	Hedgehog signaling complex
0.41	GO:0005730	nucleolus
0.40	GO:0031514	motile cilium
0.34	GO:0097730	non-motile cilium
0.30	GO:0016020	membrane

sp|P08172|ACM2_HUMAN
Muscarinic acetylcholine receptor M2
Search

CHRM2

0.81	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.76	GO:0008016	regulation of heart contraction
0.54	GO:0040012	regulation of locomotion
0.53	GO:0009615	response to virus
0.49	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.48	GO:0007271	synaptic transmission, cholinergic
0.47	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.47	GO:0006940	regulation of smooth muscle contraction
0.40	GO:1903523	negative regulation of blood circulation
0.38	GO:0046541	saliva secretion

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.61	GO:1990763	arrestin family protein binding
0.34	GO:0008144	drug binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.41	GO:0032280	symmetric synapse
0.39	GO:0043679	axon terminus
0.39	GO:0032279	asymmetric synapse
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.35	GO:0030665	clathrin-coated vesicle membrane

sp|P08173|ACM4_HUMAN
Muscarinic acetylcholine receptor M4
Search

CHRM4

0.82	Muscarinic acetylcholine receptor

0.84	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.71	GO:0040012	regulation of locomotion
0.60	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.55	GO:0008016	regulation of heart contraction
0.50	GO:0007271	synaptic transmission, cholinergic
0.49	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.44	GO:0009615	response to virus
0.42	GO:0006940	regulation of smooth muscle contraction
0.39	GO:1903523	negative regulation of blood circulation
0.36	GO:0065008	regulation of biological quality

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.48	GO:1990763	arrestin family protein binding
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0008144	drug binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.66	GO:0005887	integral component of plasma membrane
0.38	GO:0043679	axon terminus
0.38	GO:0032279	asymmetric synapse
0.38	GO:0032280	symmetric synapse
0.38	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.35	GO:0042383	sarcolemma
0.35	GO:0099572	postsynaptic specialization

sp|P08174|DAF_HUMAN
Complement decay-accelerating factor
Search

CD55

0.96	Complement decay-accelerating factor

0.56	GO:0045916	negative regulation of complement activation
0.54	GO:0006958	complement activation, classical pathway
0.51	GO:0045087	innate immune response
0.46	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation
0.45	GO:0035743	CD4-positive, alpha-beta T cell cytokine production
0.44	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway
0.44	GO:0043312	neutrophil degranulation
0.44	GO:0045730	respiratory burst
0.43	GO:0046718	viral entry into host cell
0.43	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.50	GO:0104005	hijacked molecular function
0.44	GO:0008289	lipid binding
0.38	GO:0005515	protein binding

0.50	GO:0031225	anchored component of membrane
0.47	GO:0045121	membrane raft
0.46	GO:0009986	cell surface
0.46	GO:0101003	ficolin-1-rich granule membrane
0.45	GO:0097225	sperm midpiece
0.44	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.43	GO:0070062	extracellular exosome
0.42	GO:0030133	transport vesicle
0.41	GO:0005886	plasma membrane
0.41	GO:0000139	Golgi membrane

sp|P08183|MDR1_HUMAN
Multidrug resistance protein 1
Search

0.52	Multi-drug resistance P-glycoprotein 1

0.60	GO:1903793	positive regulation of anion transport
0.59	GO:0099040	ceramide translocation
0.56	GO:0045332	phospholipid translocation
0.55	GO:2001225	regulation of chloride transport
0.55	GO:0010359	regulation of anion channel activity
0.55	GO:0055085	transmembrane transport
0.54	GO:0047484	regulation of response to osmotic stress
0.53	GO:0000086	G2/M transition of mitotic cell cycle
0.53	GO:0072089	stem cell proliferation
0.52	GO:0032414	positive regulation of ion transmembrane transporter activity

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.63	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.59	GO:0099038	ceramide-translocating ATPase activity
0.58	GO:0090555	phosphatidylethanolamine-translocating ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.47	GO:0042910	xenobiotic transmembrane transporter activity
0.44	GO:0015238	drug transmembrane transporter activity

0.57	GO:0016324	apical plasma membrane
0.54	GO:0046581	intercellular canaliculus
0.49	GO:0009986	cell surface
0.46	GO:0005925	focal adhesion
0.43	GO:0015629	actin cytoskeleton
0.43	GO:0031526	brush border membrane
0.43	GO:0070062	extracellular exosome
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.39	GO:0098857	membrane microdomain

sp|P08185|CBG_HUMAN
Corticosteroid-binding globulin
Search

SERPINA6

0.85	Corticosteroid-binding globulin

0.58	GO:0008211	glucocorticoid metabolic process
0.55	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0006953	acute-phase response
0.36	GO:0002576	platelet degranulation
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0042750	hibernation
0.35	GO:0046687	response to chromate
0.35	GO:0033986	response to methanol
0.35	GO:0006508	proteolysis
0.35	GO:0034014	response to triglyceride

0.57	GO:0004867	serine-type endopeptidase inhibitor activity
0.57	GO:0005496	steroid binding
0.44	GO:0002020	protease binding
0.42	GO:0042802	identical protein binding
0.35	GO:0008233	peptidase activity
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.42	GO:0012505	endomembrane system
0.40	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle
0.38	GO:0044444	cytoplasmic part
0.37	GO:0043229	intracellular organelle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0098588	bounding membrane of organelle

0.35

GO:0008233

sp|P08195|4F2_HUMAN
4F2 cell-surface antigen heavy chain
Search

SLC3A2

0.96	Solute carrier family 3 (Activators of dibasic and neutral amino acid transport), member 2

0.60	GO:0005975	carbohydrate metabolic process
0.45	GO:0060356	leucine import
0.42	GO:0015827	tryptophan transport
0.41	GO:0060142	regulation of syncytium formation by plasma membrane fusion
0.40	GO:0043330	response to exogenous dsRNA
0.36	GO:0050900	leukocyte migration
0.36	GO:0016049	cell growth
0.36	GO:1902475	L-alpha-amino acid transmembrane transport
0.36	GO:0035725	sodium ion transmembrane transport
0.36	GO:0006816	calcium ion transport

0.41	GO:0015175	neutral amino acid transmembrane transporter activity
0.39	GO:0045296	cadherin binding
0.38	GO:0003725	double-stranded RNA binding
0.37	GO:0005432	calcium:sodium antiporter activity
0.32	GO:0030145	manganese ion binding
0.32	GO:0004721	phosphoprotein phosphatase activity
0.31	GO:0000287	magnesium ion binding

0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.41	GO:0042470	melanosome
0.40	GO:0045177	apical part of cell
0.38	GO:0009986	cell surface
0.38	GO:0070062	extracellular exosome
0.32	GO:0005903	brush border
0.32	GO:0120038	plasma membrane bounded cell projection part
0.31	GO:0031966	mitochondrial membrane

0.32

EC:3.1.3.16

GO:0004721

sp|P08217|CEL2A_HUMAN
Chymotrypsin-like elastase family member 2A
Search

0.85	Pancreatic elastase

0.61	GO:0006508	proteolysis
0.47	GO:0061436	establishment of skin barrier
0.37	GO:0008203	cholesterol metabolic process
0.36	GO:0070268	cornification
0.34	GO:0006874	cellular calcium ion homeostasis
0.34	GO:0007596	blood coagulation
0.33	GO:0009235	cobalamin metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.45	GO:0005615	extracellular space
0.43	GO:0036457	keratohyalin granule
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P08218|CEL2B_HUMAN
Chymotrypsin-like elastase family member 2B
Search

0.85	Chymotrypsin C

0.61	GO:0006508	proteolysis
0.47	GO:0061436	establishment of skin barrier
0.39	GO:0008203	cholesterol metabolic process
0.35	GO:0070268	cornification
0.34	GO:0007586	digestion
0.34	GO:0006874	cellular calcium ion homeostasis
0.33	GO:0009235	cobalamin metabolic process
0.32	GO:0006355	regulation of transcription, DNA-templated

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0046872	metal ion binding

0.45	GO:0005615	extracellular space
0.42	GO:0036457	keratohyalin granule
0.34	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P08235|MCR_HUMAN
Mineralocorticoid receptor
Search

NR3C2

0.88	Mineralocorticoid receptor

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:1904045	cellular response to aldosterone
0.41	GO:0071386	cellular response to corticosterone stimulus
0.41	GO:0006883	cellular sodium ion homeostasis
0.41	GO:0060126	somatotropin secreting cell differentiation
0.41	GO:0071376	cellular response to corticotropin-releasing hormone stimulus

0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003707	steroid hormone receptor activity
0.51	GO:0005496	steroid binding
0.42	GO:0042562	hormone binding
0.36	GO:0005515	protein binding
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0043233	organelle lumen
0.41	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0043235	receptor complex
0.39	GO:0005829	cytosol

sp|P08236|BGLR_HUMAN
Beta-glucuronidase
Search

GUSB

0.60	Beta-glucuronidase

0.60	GO:0005975	carbohydrate metabolic process
0.36	GO:0046677	response to antibiotic
0.36	GO:0030214	hyaluronan catabolic process
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0006907	pinocytosis
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0006898	receptor-mediated endocytosis

0.81	GO:0004566	beta-glucuronidase activity
0.50	GO:0019904	protein domain specific binding
0.48	GO:0005102	receptor binding
0.34	GO:0030246	carbohydrate binding

0.74	GO:0005764	lysosome
0.49	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.36	GO:0005775	vacuolar lumen
0.34	GO:0009986	cell surface
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.2.1.31

GO:0004566

sp|P08237|PFKAM_HUMAN
ATP-dependent 6-phosphofructokinase, muscle type
Search

PFKM

0.46	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.57	GO:0061718	glucose catabolic process to pyruvate
0.57	GO:0006735	NADH regeneration
0.55	GO:0046716	muscle cell cellular homeostasis
0.55	GO:0032024	positive regulation of insulin secretion
0.52	GO:0042593	glucose homeostasis
0.52	GO:0005980	glycogen catabolic process
0.50	GO:0046835	carbohydrate phosphorylation
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II

0.79	GO:0003872	6-phosphofructokinase activity
0.58	GO:0070061	fructose binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008022	protein C-terminus binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019900	kinase binding
0.50	GO:0046872	metal ion binding
0.50	GO:0042803	protein homodimerization activity
0.39	GO:0070095	fructose-6-phosphate binding

0.58	GO:0005945	6-phosphofructokinase complex
0.55	GO:0097228	sperm principal piece
0.53	GO:0016324	apical plasma membrane
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.7.1.11

GO:0003872

sp|P08238|HS90B_HUMAN
Heat shock protein HSP 90-beta
Search

HSP90AB1

0.71	Heat shock cognate protein HSP 90-beta

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.59	GO:1901389	negative regulation of transforming growth factor beta activation
0.56	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.56	GO:1905323	telomerase holoenzyme complex assembly
0.55	GO:0071157	negative regulation of cell cycle arrest
0.55	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.54	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.54	GO:2000010	positive regulation of protein localization to cell surface
0.54	GO:0060330	regulation of response to interferon-gamma

0.71	GO:0051082	unfolded protein binding
0.55	GO:0043008	ATP-dependent protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:1990226	histone methyltransferase binding
0.54	GO:0070182	DNA polymerase binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0097718	disordered domain specific binding
0.52	GO:0042826	histone deacetylase binding

0.55	GO:0034751	aryl hydrocarbon receptor complex
0.50	GO:0008180	COP9 signalosome
0.46	GO:0005576	extracellular region
0.46	GO:0005829	cytosol
0.43	GO:0042470	melanosome
0.42	GO:1990917	ooplasm
0.42	GO:1990913	sperm head plasma membrane
0.41	GO:0005739	mitochondrion
0.40	GO:0031526	brush border membrane
0.40	GO:0016234	inclusion body

sp|P08240|SRPRA_HUMAN
Signal recognition particle receptor subunit alpha
Search

SRPRA

0.87	Signal recognition particle receptor subunit alpha

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.36	GO:0036498	IRE1-mediated unfolded protein response

0.84	GO:0005047	signal recognition particle binding
0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003723	RNA binding

0.84	GO:0005785	signal recognition particle receptor complex
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P08243|ASNS_HUMAN
Asparagine synthetase [glutamine-hydrolyzing]
Search

ASNS

0.63	Asparagine synthetase

0.75	GO:0006529	asparagine biosynthetic process
0.66	GO:0006541	glutamine metabolic process
0.56	GO:0042149	cellular response to glucose starvation
0.55	GO:0045931	positive regulation of mitotic cell cycle
0.53	GO:0043066	negative regulation of apoptotic process
0.43	GO:0070982	L-asparagine metabolic process
0.40	GO:0031427	response to methotrexate
0.39	GO:0032354	response to follicle-stimulating hormone
0.38	GO:0001889	liver development
0.38	GO:0043200	response to amino acid

0.76	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042803	protein homodimerization activity
0.34	GO:0048037	cofactor binding

0.49

GO:0005829

cytosol

0.76

EC:6.3.5.4

GO:0004066

sp|P08246|ELNE_HUMAN
Neutrophil elastase
Search

ELANE

0.85	Neutrophil elastase

0.62	GO:0002812	biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.61	GO:0070947	neutrophil mediated killing of fungus
0.61	GO:0045079	negative regulation of chemokine biosynthetic process
0.61	GO:0006508	proteolysis
0.61	GO:0045415	negative regulation of interleukin-8 biosynthetic process
0.60	GO:0070945	neutrophil mediated killing of gram-negative bacterium
0.60	GO:0002438	acute inflammatory response to antigenic stimulus
0.59	GO:0050900	leukocyte migration
0.59	GO:0045416	positive regulation of interleukin-8 biosynthetic process
0.58	GO:0001878	response to yeast

0.69	GO:0004252	serine-type endopeptidase activity
0.57	GO:0001106	RNA polymerase II transcription corepressor activity
0.56	GO:0002020	protease binding
0.56	GO:0019955	cytokine binding
0.56	GO:0008201	heparin binding
0.43	GO:0005102	receptor binding
0.41	GO:0008061	chitin binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0000049	tRNA binding

0.59	GO:0030141	secretory granule
0.55	GO:0017053	transcriptional repressor complex
0.54	GO:0044421	extracellular region part
0.52	GO:0009986	cell surface
0.49	GO:0005766	primary lysosome
0.49	GO:0060205	cytoplasmic vesicle lumen
0.49	GO:0005775	vacuolar lumen
0.46	GO:0044853	plasma membrane raft
0.42	GO:0005829	cytosol
0.34	GO:0005765	lysosomal membrane

0.69

GO:0004252

sp|P08247|SYPH_HUMAN
Synaptophysin
Search

SYP

0.95	Synaptophysin a

0.77	GO:0048168	regulation of neuronal synaptic plasticity
0.54	GO:0048488	synaptic vesicle endocytosis
0.48	GO:0071310	cellular response to organic substance
0.42	GO:2000474	regulation of opioid receptor signaling pathway
0.38	GO:0045920	negative regulation of exocytosis
0.36	GO:0048499	synaptic vesicle membrane organization
0.36	GO:0016188	synaptic vesicle maturation
0.35	GO:0043029	T cell homeostasis
0.35	GO:0050856	regulation of T cell receptor signaling pathway
0.35	GO:0007268	chemical synaptic transmission

0.54	GO:0042169	SH2 domain binding
0.53	GO:0015485	cholesterol binding
0.49	GO:0042802	identical protein binding
0.38	GO:0017075	syntaxin-1 binding
0.36	GO:0051020	GTPase binding
0.35	GO:0008331	high voltage-gated calcium channel activity
0.35	GO:0043621	protein self-association
0.34	GO:0032403	protein complex binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0003924	GTPase activity

0.82	GO:0008021	synaptic vesicle
0.58	GO:0099501	exocytic vesicle membrane
0.54	GO:0060076	excitatory synapse
0.54	GO:0042734	presynaptic membrane
0.53	GO:0043195	terminal bouton
0.53	GO:0031594	neuromuscular junction
0.52	GO:0048786	presynaptic active zone
0.47	GO:0031301	integral component of organelle membrane
0.40	GO:0030054	cell junction
0.38	GO:0042584	chromaffin granule membrane

sp|P08253|MMP2_HUMAN
72 kDa type IV collagenase
Search

MMP2

0.50	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.41	GO:0001957	intramembranous ossification
0.41	GO:0060346	bone trabecula formation
0.41	GO:0001955	blood vessel maturation
0.41	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.41	GO:0007566	embryo implantation
0.41	GO:0030574	collagen catabolic process
0.41	GO:0060325	face morphogenesis
0.41	GO:0035987	endodermal cell differentiation
0.40	GO:0071230	cellular response to amino acid stimulus

0.70	GO:0004222	metalloendopeptidase activity
0.62	GO:0008270	zinc ion binding
0.39	GO:0005509	calcium ion binding
0.37	GO:0016746	transferase activity, transferring acyl groups
0.30	GO:0005515	protein binding
0.30	GO:0004252	serine-type endopeptidase activity

0.73	GO:0031012	extracellular matrix
0.39	GO:0030017	sarcomere
0.38	GO:0005615	extracellular space
0.36	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane
0.30	GO:0005634	nucleus

0.70

GO:0004222

sp|P08254|MMP3_HUMAN
Stromelysin-1
Search

0.70	Matrix metalloproteinase

0.66	GO:0030574	collagen catabolic process
0.61	GO:0006508	proteolysis
0.57	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.55	GO:0032461	positive regulation of protein oligomerization
0.52	GO:0022617	extracellular matrix disassembly
0.50	GO:0003417	growth plate cartilage development
0.49	GO:0001958	endochondral ossification
0.49	GO:0030282	bone mineralization
0.48	GO:0030334	regulation of cell migration
0.40	GO:1903209	positive regulation of oxidative stress-induced cell death

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.49	GO:0005518	collagen binding
0.45	GO:0005509	calcium ion binding
0.38	GO:0004252	serine-type endopeptidase activity
0.36	GO:0001047	core promoter binding
0.34	GO:0001968	fibronectin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0048306	calcium-dependent protein binding
0.34	GO:0043565	sequence-specific DNA binding

0.74	GO:0031012	extracellular matrix
0.42	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.40	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.35	GO:0005581	collagen trimer
0.35	GO:0030425	dendrite
0.35	GO:0044297	cell body
0.35	GO:0046581	intercellular canaliculus
0.34	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion

0.70

GO:0004222

sp|P08263|GSTA1_HUMAN
Glutathione S-transferase A1
Search

0.42	Glutathione S-transferase alpha I

0.47	GO:0006749	glutathione metabolic process
0.46	GO:0043651	linoleic acid metabolic process
0.45	GO:0060429	epithelium development
0.43	GO:0042221	response to chemical
0.42	GO:0046222	aflatoxin metabolic process
0.42	GO:0030154	cell differentiation
0.41	GO:1901377	organic heteropentacyclic compound catabolic process
0.40	GO:1901685	glutathione derivative metabolic process
0.39	GO:0001823	mesonephros development
0.38	GO:0007568	aging

0.76	GO:0004364	glutathione transferase activity
0.43	GO:0004602	glutathione peroxidase activity
0.39	GO:0043295	glutathione binding
0.34	GO:0005515	protein binding
0.34	GO:0008144	drug binding

0.47	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.39	GO:0005640	nuclear outer membrane

0.76

GO:0004364

sp|P08294|SODE_HUMAN
Extracellular superoxide dismutase [Cu-Zn]
Search

SOD3

0.52	Extracellular superoxide dismutase [Cu-Zn]

0.75	GO:0006801	superoxide metabolic process
0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.68	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0001666	response to hypoxia
0.40	GO:0046688	response to copper ion
0.38	GO:0071457	cellular response to ozone
0.38	GO:0030001	metal ion transport
0.38	GO:0071484	cellular response to light intensity

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding
0.36	GO:0016530	metallochaperone activity
0.36	GO:0008201	heparin binding
0.35	GO:0008047	enzyme activator activity
0.32	GO:0004842	ubiquitin-protein transferase activity

0.50	GO:0005615	extracellular space
0.48	GO:0031012	extracellular matrix
0.38	GO:0005634	nucleus
0.38	GO:0005796	Golgi lumen
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005829	cytosol
0.34	GO:0032839	dendrite cytoplasm
0.34	GO:0043025	neuronal cell body
0.33	GO:0005777	peroxisome
0.33	GO:0005739	mitochondrion

0.77	EC:1.15.1.1	GO:0004784
0.32	KEGG:R03876	GO:0004842

sp|P08311|CATG_HUMAN
Cathepsin G
Search

CTSG

0.92	Endogenous granzyme B

0.65	GO:0001909	leukocyte mediated cytotoxicity
0.63	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.62	GO:0002443	leukocyte mediated immunity
0.61	GO:0006508	proteolysis
0.55	GO:0006952	defense response
0.55	GO:0006955	immune response
0.52	GO:0051851	modification by host of symbiont morphology or physiology
0.51	GO:0044130	negative regulation of growth of symbiont in host
0.50	GO:0009620	response to fungus
0.50	GO:0051883	killing of cells in other organism involved in symbiotic interaction

0.69	GO:0004252	serine-type endopeptidase activity
0.49	GO:0008201	heparin binding
0.35	GO:0005515	protein binding
0.34	GO:0042277	peptide binding

0.64	GO:0030141	secretory granule
0.48	GO:0010494	cytoplasmic stress granule
0.47	GO:0031012	extracellular matrix
0.46	GO:0005615	extracellular space
0.39	GO:0005886	plasma membrane
0.36	GO:0005764	lysosome
0.36	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0005775	vacuolar lumen
0.35	GO:1903561	extracellular vesicle
0.35	GO:0009986	cell surface

0.69

GO:0004252

sp|P08319|ADH4_HUMAN
Alcohol dehydrogenase 4
Search

0.48	Alcohol dehydrogenase class VII

0.70	GO:0006067	ethanol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0001523	retinoid metabolic process
0.48	GO:0034754	cellular hormone metabolic process
0.46	GO:0046164	alcohol catabolic process
0.44	GO:1901661	quinone metabolic process
0.43	GO:0006081	cellular aldehyde metabolic process
0.40	GO:0045471	response to ethanol
0.40	GO:0009617	response to bacterium
0.39	GO:1900116	extracellular negative regulation of signal transduction

0.72	GO:0004024	alcohol dehydrogenase activity, zinc-dependent
0.71	GO:0035276	ethanol binding
0.63	GO:0008270	zinc ion binding
0.52	GO:0019841	retinol binding
0.52	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.52	GO:0019115	benzaldehyde dehydrogenase activity
0.51	GO:0004745	retinol dehydrogenase activity
0.51	GO:0005503	all-trans retinal binding
0.49	GO:0004032	alditol:NADP+ 1-oxidoreductase activity
0.47	GO:0003960	NADPH:quinone reductase activity

0.45	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.35	GO:0044446	intracellular organelle part
0.33	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.32	GO:0005840	ribosome
0.32	GO:0031090	organelle membrane

0.52	EC:1.1.1.284	GO:0051903
0.52	KEGG:R06983 KEGG:R07140	GO:0051903

sp|P08397|HEM3_HUMAN
Porphobilinogen deaminase
Search

HMBS

0.47	Hydroxymethylbilane synthase a

0.79	GO:0018160	peptidyl-pyrromethane cofactor linkage
0.69	GO:0033014	tetrapyrrole biosynthetic process
0.45	GO:0042168	heme metabolic process
0.45	GO:0046148	pigment biosynthetic process
0.42	GO:0051188	cofactor biosynthetic process

0.80

GO:0004418

hydroxymethylbilane synthase activity

0.37

GO:0005737

cytoplasm

0.80	EC:2.5.1.61	GO:0004418
0.80	KEGG:R00084	GO:0004418

sp|P08473|NEP_HUMAN
Neprilysin
Search

MME

0.91	Membrane metallo-endopeptidase

0.62	GO:0071492	cellular response to UV-A
0.61	GO:0071493	cellular response to UV-B
0.61	GO:0006508	proteolysis
0.60	GO:0046449	creatinine metabolic process
0.60	GO:0090399	replicative senescence
0.60	GO:0050435	amyloid-beta metabolic process
0.58	GO:0019233	sensory perception of pain
0.57	GO:0001822	kidney development
0.55	GO:0071345	cellular response to cytokine stimulus
0.40	GO:0097242	amyloid-beta clearance

0.70	GO:0004222	metalloendopeptidase activity
0.48	GO:0008238	exopeptidase activity
0.48	GO:0042277	peptide binding
0.47	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.58	GO:0005903	brush border
0.57	GO:0044306	neuron projection terminus
0.56	GO:0008021	synaptic vesicle
0.55	GO:0030425	dendrite
0.55	GO:0030424	axon
0.43	GO:0005886	plasma membrane
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.35	GO:0030667	secretory granule membrane
0.33	GO:0005794	Golgi apparatus

0.70

GO:0004222

sp|P08476|INHBA_HUMAN
Inhibin beta A chain
Search

INHBA

0.97	Inhibin beta A subunit

0.76	GO:0010469	regulation of receptor activity
0.65	GO:0042701	progesterone secretion
0.64	GO:0046880	regulation of follicle-stimulating hormone secretion
0.63	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.63	GO:0042541	hemoglobin biosynthetic process
0.62	GO:0060279	positive regulation of ovulation
0.62	GO:0032924	activin receptor signaling pathway
0.62	GO:0045648	positive regulation of erythrocyte differentiation
0.61	GO:0021773	striatal medium spiny neuron differentiation
0.61	GO:0061029	eyelid development in camera-type eye

0.78	GO:0008083	growth factor activity
0.73	GO:0005179	hormone activity
0.62	GO:0070699	type II activin receptor binding
0.58	GO:0017046	peptide hormone binding
0.58	GO:0005125	cytokine activity
0.52	GO:0042802	identical protein binding
0.48	GO:0005160	transforming growth factor beta receptor binding
0.43	GO:0034711	inhibin binding
0.39	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.54	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0043234	protein complex

sp|P08493|MGP_HUMAN
Matrix Gla protein
Search

MGP

0.94	Matrix Gla protein (Fragment)

0.73	GO:0030500	regulation of bone mineralization
0.48	GO:0051216	cartilage development
0.48	GO:0001503	ossification
0.44	GO:0030154	cell differentiation
0.37	GO:0098743	cell aggregation
0.37	GO:0009653	anatomical structure morphogenesis
0.36	GO:0051384	response to glucocorticoid
0.36	GO:0051592	response to calcium ion
0.36	GO:0030324	lung development
0.36	GO:0009612	response to mechanical stimulus

0.70	GO:0005509	calcium ion binding
0.49	GO:0005201	extracellular matrix structural constituent
0.39	GO:0008147	structural constituent of bone
0.37	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.39	GO:0070062	extracellular exosome
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P08514|ITA2B_HUMAN
Integrin alpha-IIb
Search

0.88	Integrin alpha-IIb

0.79	GO:0007229	integrin-mediated signaling pathway
0.71	GO:0007155	cell adhesion
0.49	GO:0001704	formation of primary germ layer
0.46	GO:0048731	system development
0.46	GO:0000904	cell morphogenesis involved in differentiation
0.46	GO:0009888	tissue development
0.45	GO:0048522	positive regulation of cellular process
0.45	GO:0042060	wound healing
0.45	GO:0040017	positive regulation of locomotion
0.45	GO:0030334	regulation of cell migration

0.61	GO:0050840	extracellular matrix binding
0.54	GO:0042802	identical protein binding
0.45	GO:0070051	fibrinogen binding
0.43	GO:0005178	integrin binding
0.43	GO:1990430	extracellular matrix protein binding
0.43	GO:0038132	neuregulin binding
0.43	GO:0019960	C-X3-C chemokine binding
0.42	GO:0031994	insulin-like growth factor I binding
0.42	GO:0001968	fibronectin binding
0.42	GO:0017134	fibroblast growth factor binding

0.80	GO:0008305	integrin complex
0.61	GO:0005925	focal adhesion
0.60	GO:0009897	external side of plasma membrane
0.57	GO:0070062	extracellular exosome
0.43	GO:0032587	ruffle membrane
0.43	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.43	GO:0012505	endomembrane system
0.42	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.42	GO:0031258	lamellipodium membrane
0.42	GO:0031528	microvillus membrane

sp|P08519|APOA_HUMAN
Apolipoprotein(a)
Search

0.10	Apolipoprotein(a)

0.68	GO:0042730	fibrinolysis
0.64	GO:0048771	tissue remodeling
0.63	GO:0007596	blood coagulation
0.61	GO:0006508	proteolysis
0.47	GO:0052213	interaction with symbiont via secreted substance involved in symbiotic interaction
0.47	GO:0071674	mononuclear cell migration
0.47	GO:0045445	myoblast differentiation
0.47	GO:0046716	muscle cell cellular homeostasis
0.46	GO:0052212	modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction
0.46	GO:0060707	trophoblast giant cell differentiation

0.69	GO:0004252	serine-type endopeptidase activity
0.46	GO:1904854	proteasome core complex binding
0.46	GO:0019900	kinase binding
0.46	GO:1990405	protein antigen binding
0.45	GO:0034185	apolipoprotein binding
0.42	GO:0019904	protein domain specific binding
0.42	GO:0051087	chaperone binding
0.41	GO:0005102	receptor binding
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0030545	receptor regulator activity

0.53	GO:0005576	extracellular region
0.46	GO:0019897	extrinsic component of plasma membrane
0.43	GO:0009897	external side of plasma membrane
0.39	GO:0044279	other organism membrane
0.38	GO:0044216	other organism cell
0.33	GO:0031982	vesicle
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0032991	macromolecular complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P08559|ODPA_HUMAN
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
Search

PDHA1

0.52	Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

0.79	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0006101	citrate metabolic process
0.42	GO:0019362	pyridine nucleotide metabolic process
0.41	GO:0006091	generation of precursor metabolites and energy
0.41	GO:0006006	glucose metabolic process
0.37	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate

0.78	GO:0004738	pyruvate dehydrogenase activity
0.75	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
0.45	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0005515	protein binding

0.55	GO:0043231	intracellular membrane-bounded organelle
0.49	GO:0045254	pyruvate dehydrogenase complex
0.47	GO:0043209	myelin sheath
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0043232	intracellular non-membrane-bounded organelle

0.75

EC:1.2.4

GO:0016624

sp|P08567|PLEK_HUMAN
Pleckstrin
Search

PLEK

0.97	Pleckstrin

0.63	GO:0010925	positive regulation of inositol-polyphosphate 5-phosphatase activity
0.63	GO:0010920	negative regulation of inositol phosphate biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.62	GO:0030845	phospholipase C-inhibiting G-protein coupled receptor signaling pathway
0.62	GO:0060305	regulation of cell diameter
0.61	GO:0070560	protein secretion by platelet
0.60	GO:0033625	positive regulation of integrin activation
0.60	GO:0010572	positive regulation of platelet activation
0.59	GO:0070493	thrombin-activated receptor signaling pathway
0.59	GO:0031529	ruffle organization

0.59	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.59	GO:0005080	protein kinase C binding
0.52	GO:0042803	protein homodimerization activity

0.58	GO:0032587	ruffle membrane
0.45	GO:0005622	intracellular
0.34	GO:0005576	extracellular region

sp|P08571|CD14_HUMAN
Monocyte differentiation antigen CD14
Search

CD14

0.97	Monocyte differentiation antigen CD14

0.78	GO:0006954	inflammatory response
0.77	GO:0045087	innate immune response
0.70	GO:0071727	cellular response to triacyl bacterial lipopeptide
0.70	GO:0071726	cellular response to diacyl bacterial lipopeptide
0.67	GO:0070391	response to lipoteichoic acid
0.67	GO:2000484	positive regulation of interleukin-8 secretion
0.66	GO:0034142	toll-like receptor 4 signaling pathway
0.66	GO:0032760	positive regulation of tumor necrosis factor production
0.66	GO:0032729	positive regulation of interferon-gamma production
0.66	GO:0031663	lipopolysaccharide-mediated signaling pathway

0.68	GO:0070891	lipoteichoic acid binding
0.68	GO:0071723	lipopeptide binding
0.62	GO:0001530	lipopolysaccharide binding
0.40	GO:0016019	peptidoglycan receptor activity
0.40	GO:0001847	opsonin receptor activity
0.37	GO:0005515	protein binding

0.67	GO:0031362	anchored component of external side of plasma membrane
0.66	GO:0046696	lipopolysaccharide receptor complex
0.62	GO:0098857	membrane microdomain
0.56	GO:0005794	Golgi apparatus
0.42	GO:0005576	extracellular region
0.39	GO:0030667	secretory granule membrane
0.38	GO:0010008	endosome membrane

sp|P08572|CO4A2_HUMAN
Collagen alpha-2(IV) chain
Search

COL4A2

0.79	Collagen type IV alpha 2 chain

0.62	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.60	GO:0035987	endodermal cell differentiation
0.58	GO:0016525	negative regulation of angiogenesis
0.57	GO:0071560	cellular response to transforming growth factor beta stimulus
0.45	GO:0006351	transcription, DNA-templated
0.42	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0030198	extracellular matrix organization
0.39	GO:0014823	response to activity
0.38	GO:0007568	aging
0.37	GO:0001525	angiogenesis

0.81	GO:0005201	extracellular matrix structural constituent
0.34	GO:0005515	protein binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005604	basement membrane
0.78	GO:0005581	collagen trimer
0.64	GO:0098645	collagen network
0.52	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0016459	myosin complex

sp|P08574|CY1_HUMAN
Cytochrome c1, heme protein, mitochondrial
Search

CYC1

0.63	Cytochrome c1, heme protein, mitochondrial

0.61	GO:0022900	electron transport chain
0.51	GO:0042776	mitochondrial ATP synthesis coupled proton transport
0.42	GO:0006119	oxidative phosphorylation
0.41	GO:0045333	cellular respiration
0.39	GO:0033762	response to glucagon

0.63	GO:0020037	heme binding
0.62	GO:0009055	electron transfer activity
0.51	GO:0046872	metal ion binding
0.34	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.33	GO:0005515	protein binding

0.49	GO:0005750	mitochondrial respiratory chain complex III
0.34	GO:0005634	nucleus
0.34	GO:0042765	GPI-anchor transamidase complex

0.34

GO:0016681

sp|P08575|PTPRC_HUMAN
Receptor-type tyrosine-protein phosphatase C
Search

PTPRC

0.94	Receptor-type tyrosine-protein phosphatase C

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.65	GO:0050852	T cell receptor signaling pathway
0.42	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.41	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway
0.41	GO:0042100	B cell proliferation
0.41	GO:0050853	B cell receptor signaling pathway
0.40	GO:0042102	positive regulation of T cell proliferation
0.40	GO:0051209	release of sequestered calcium ion into cytosol
0.40	GO:0030217	T cell differentiation
0.40	GO:0006469	negative regulation of protein kinase activity

0.75	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0019901	protein kinase binding
0.37	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:0008201	heparin binding
0.30	GO:0004888	transmembrane signaling receptor activity

0.40	GO:0005925	focal adhesion
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0009897	external side of plasma membrane
0.36	GO:0098857	membrane microdomain
0.30	GO:0005615	extracellular space
0.30	GO:0031410	cytoplasmic vesicle
0.30	GO:0098588	bounding membrane of organelle
0.30	GO:0044446	intracellular organelle part
0.30	GO:0043230	extracellular organelle
0.30	GO:0012505	endomembrane system

0.75

EC:3.1.3.48

GO:0004725

sp|P08579|RU2B_HUMAN
U2 small nuclear ribonucleoprotein B''
Search

SNRPB2

0.89	Small nuclear ribonucleoprotein polypeptide B''

0.44

GO:0000398

mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.39	GO:0070990	snRNP binding
0.35	GO:0005515	protein binding

0.60	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.52	GO:0001650	fibrillar center
0.51	GO:0120114	Sm-like protein family complex
0.50	GO:0016607	nuclear speck
0.43	GO:1902494	catalytic complex
0.30	GO:0016021	integral component of membrane

sp|P08581|MET_HUMAN
Hepatocyte growth factor receptor
Search

MET

0.95	Hepatocyte growth factor receptor

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.74	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.72	GO:2001028	positive regulation of endothelial cell chemotaxis
0.69	GO:0050918	positive chemotaxis
0.66	GO:0071526	semaphorin-plexin signaling pathway
0.57	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.57	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.56	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death
0.56	GO:0001886	endothelial cell morphogenesis
0.55	GO:0051497	negative regulation of stress fiber assembly

0.76	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0019903	protein phosphatase binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0043274	phospholipase binding
0.36	GO:0043548	phosphatidylinositol 3-kinase binding

0.55	GO:0009925	basal plasma membrane
0.37	GO:0098794	postsynapse
0.37	GO:0009986	cell surface
0.36	GO:0060076	excitatory synapse
0.36	GO:0036126	sperm flagellum
0.36	GO:0032279	asymmetric synapse
0.36	GO:0005576	extracellular region
0.36	GO:0008290	F-actin capping protein complex
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite

0.76	EC:2.7.10.1	GO:0004714
0.37	KEGG:R04545	GO:0046934

sp|P08582|TRFM_HUMAN
Melanotransferrin
Search

MELTF

0.71	Melanotransferrin

0.73	GO:0010756	positive regulation of plasminogen activation
0.73	GO:0090091	positive regulation of extracellular matrix disassembly
0.72	GO:0097286	iron ion import
0.71	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.56	GO:0055072	iron ion homeostasis
0.45	GO:0046916	cellular transition metal ion homeostasis
0.44	GO:0015682	ferric iron transport
0.41	GO:0042127	regulation of cell proliferation
0.41	GO:0001558	regulation of cell growth
0.40	GO:0071281	cellular response to iron ion

0.54	GO:0005506	iron ion binding
0.44	GO:0015091	ferric iron transmembrane transporter activity
0.40	GO:1990459	transferrin receptor binding
0.37	GO:0004601	peroxidase activity
0.35	GO:0020037	heme binding
0.35	GO:0043539	protein serine/threonine kinase activator activity
0.35	GO:0008201	heparin binding
0.35	GO:0001530	lipopolysaccharide binding
0.35	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.34	GO:0004252	serine-type endopeptidase activity

0.71	GO:0005615	extracellular space
0.66	GO:0046658	anchored component of plasma membrane
0.62	GO:0009986	cell surface
0.42	GO:0031982	vesicle
0.41	GO:0043230	extracellular organelle
0.40	GO:1990712	HFE-transferrin receptor complex
0.40	GO:0009925	basal plasma membrane
0.39	GO:0012505	endomembrane system
0.39	GO:0016324	apical plasma membrane
0.38	GO:0048471	perinuclear region of cytoplasm

0.37	EC:1.11.1.7	GO:0004601
0.37	KEGG:R03532	GO:0004601

sp|P08588|ADRB1_HUMAN
Beta-1 adrenergic receptor
Search

0.96	Beta-1 adrenergic receptor

0.84	GO:0071875	adrenergic receptor signaling pathway
0.82	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.73	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.73	GO:0045823	positive regulation of heart contraction
0.69	GO:0001659	temperature homeostasis
0.68	GO:0002024	diet induced thermogenesis
0.67	GO:0040015	negative regulation of multicellular organism growth
0.66	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine
0.65	GO:0043950	positive regulation of cAMP-mediated signaling
0.65	GO:0050873	brown fat cell differentiation

0.85	GO:0004939	beta-adrenergic receptor activity
0.67	GO:0031690	adrenergic receptor binding
0.65	GO:0051380	norepinephrine binding
0.59	GO:0051379	epinephrine binding
0.58	GO:0005057	signal transducer activity, downstream of receptor
0.58	GO:0030165	PDZ domain binding
0.58	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.55	GO:0046983	protein dimerization activity
0.48	GO:0042802	identical protein binding
0.37	GO:0050824	water binding

0.59	GO:0005769	early endosome
0.54	GO:0005886	plasma membrane
0.50	GO:0043235	receptor complex
0.37	GO:0005634	nucleus
0.36	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

0.34

EC:2.6.1

GO:0008483

sp|P08590|MYL3_HUMAN
Myosin light chain 3
Search

MYL3

0.93	Myosin light chain 1, cardiac muscle

0.66	GO:0002026	regulation of the force of heart contraction
0.64	GO:0060048	cardiac muscle contraction
0.57	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.56	GO:0006942	regulation of striated muscle contraction
0.50	GO:0032781	positive regulation of ATPase activity
0.39	GO:0007519	skeletal muscle tissue development
0.37	GO:0030049	muscle filament sliding
0.35	GO:0043520	regulation of myosin II filament assembly
0.35	GO:0055005	ventricular cardiac myofibril assembly
0.34	GO:0045214	sarcomere organization

0.69	GO:0005509	calcium ion binding
0.63	GO:0003785	actin monomer binding
0.49	GO:0051015	actin filament binding
0.38	GO:0032038	myosin II heavy chain binding
0.37	GO:0003774	motor activity
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0004252	serine-type endopeptidase activity

0.64	GO:0031672	A band
0.55	GO:0031674	I band
0.43	GO:0016459	myosin complex
0.35	GO:0005829	cytosol

0.33

GO:0004252

sp|P08603|CFAH_HUMAN
Complement factor H
Search

CFH

0.81	Complement regulator factor H

0.81	GO:0006956	complement activation
0.62	GO:0030449	regulation of complement activation
0.59	GO:0045087	innate immune response
0.58	GO:0045919	positive regulation of cytolysis
0.48	GO:0032091	negative regulation of protein binding
0.43	GO:0016032	viral process

0.81	GO:0043395	heparan sulfate proteoglycan binding
0.77	GO:0008201	heparin binding
0.50	GO:0001851	complement component C3b binding
0.45	GO:0042803	protein homodimerization activity
0.44	GO:0046982	protein heterodimerization activity

0.54	GO:0072562	blood microparticle
0.52	GO:0070062	extracellular exosome
0.40	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P08620|FGF4_HUMAN
Fibroblast growth factor 4
Search

FGF4

0.62	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0060591	chondroblast differentiation
0.58	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.57	GO:0010463	mesenchymal cell proliferation
0.57	GO:0001502	cartilage condensation
0.56	GO:0060363	cranial suture morphogenesis
0.55	GO:0060561	apoptotic process involved in morphogenesis
0.54	GO:0035116	embryonic hindlimb morphogenesis
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.83	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0008201	heparin binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.65	GO:0005576	extracellular region
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P08621|RU17_HUMAN
U1 small nuclear ribonucleoprotein 70 kDa
Search

SNRNP70

0.90	Small nuclear ribonucleoprotein U1 subunit 70

0.57	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.54	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0060218	hematopoietic stem cell differentiation
0.43	GO:0071300	cellular response to retinoic acid
0.42	GO:0071356	cellular response to tumor necrosis factor
0.42	GO:0071560	cellular response to transforming growth factor beta stimulus
0.37	GO:0061084	negative regulation of protein refolding
0.37	GO:1904715	negative regulation of chaperone-mediated autophagy
0.35	GO:0043462	regulation of ATPase activity
0.33	GO:0099643	signal release from synapse

0.82	GO:0030619	U1 snRNA binding
0.46	GO:0003729	mRNA binding
0.45	GO:1990446	U1 snRNP binding
0.34	GO:0005515	protein binding

0.58	GO:0019013	viral nucleocapsid
0.58	GO:0005685	U1 snRNP
0.55	GO:0005681	spliceosomal complex
0.50	GO:0005654	nucleoplasm
0.35	GO:0005737	cytoplasm
0.33	GO:0048786	presynaptic active zone
0.30	GO:0016020	membrane

sp|P08631|HCK_HUMAN
Tyrosine-protein kinase HCK
Search

HCK

0.58	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.49	GO:0046777	protein autophosphorylation
0.48	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.48	GO:0070667	negative regulation of mast cell proliferation
0.47	GO:2000670	positive regulation of dendritic cell apoptotic process
0.47	GO:0002513	tolerance induction to self antigen
0.46	GO:0002431	Fc receptor mediated stimulatory signaling pathway
0.46	GO:0002774	Fc receptor mediated inhibitory signaling pathway
0.46	GO:0002576	platelet degranulation
0.46	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway

0.81	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005102	receptor binding
0.45	GO:0140031	phosphorylation-dependent protein binding
0.43	GO:0044325	ion channel binding
0.42	GO:0017124	SH3 domain binding
0.41	GO:0032403	protein complex binding

0.48	GO:0005654	nucleoplasm
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0045121	membrane raft
0.42	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005794	Golgi apparatus
0.35	GO:0034666	integrin alpha2-beta1 complex
0.35	GO:0042629	mast cell granule
0.35	GO:0030061	mitochondrial crista
0.34	GO:0014069	postsynaptic density
0.34	GO:0005913	cell-cell adherens junction

0.81

GO:0004715

sp|P08637|FCG3A_HUMAN
Low affinity immunoglobulin gamma Fc region receptor III-A
Search

0.95	Low affinity immunoglobulin gamma Fc region receptor III-A

0.51	GO:0038094	Fc-gamma receptor signaling pathway
0.48	GO:0002274	myeloid leukocyte activation
0.48	GO:0038095	Fc-epsilon receptor signaling pathway
0.48	GO:0045780	positive regulation of bone resorption
0.40	GO:0071219	cellular response to molecule of bacterial origin
0.40	GO:0051930	regulation of sensory perception of pain
0.39	GO:0002252	immune effector process
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:0006909	phagocytosis
0.39	GO:0001810	regulation of type I hypersensitivity

0.52	GO:0019770	IgG receptor activity
0.50	GO:0019864	IgG binding
0.50	GO:0019767	IgE receptor activity
0.37	GO:0019863	IgE binding
0.35	GO:0001540	amyloid-beta binding
0.34	GO:0034987	immunoglobulin receptor binding
0.33	GO:0005057	signal transducer activity, downstream of receptor

0.46	GO:0009986	cell surface
0.41	GO:0070062	extracellular exosome
0.41	GO:0098552	side of membrane
0.39	GO:0005886	plasma membrane
0.36	GO:0030667	secretory granule membrane
0.35	GO:0031225	anchored component of membrane
0.35	GO:0043197	dendritic spine
0.35	GO:0044297	cell body
0.34	GO:0055037	recycling endosome
0.33	GO:0098857	membrane microdomain

sp|P08648|ITA5_HUMAN
Integrin alpha-5
Search

ITGA5

0.90	Integrin alpha 5 (Fibronectin receptor alpha)

0.78	GO:0007229	integrin-mediated signaling pathway
0.70	GO:0007155	cell adhesion
0.63	GO:0035987	endodermal cell differentiation
0.63	GO:0035313	wound healing, spreading of epidermal cells
0.62	GO:2000811	negative regulation of anoikis
0.61	GO:1903672	positive regulation of sprouting angiogenesis
0.60	GO:0007044	cell-substrate junction assembly
0.59	GO:0007613	memory
0.59	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.45	GO:0030335	positive regulation of cell migration

0.61	GO:0005178	integrin binding
0.44	GO:0001968	fibronectin binding
0.43	GO:1990430	extracellular matrix protein binding
0.43	GO:0038132	neuregulin binding
0.43	GO:0019960	C-X3-C chemokine binding
0.43	GO:0001846	opsonin binding
0.43	GO:0031994	insulin-like growth factor I binding
0.42	GO:0017134	fibroblast growth factor binding
0.42	GO:0005080	protein kinase C binding
0.42	GO:0050840	extracellular matrix binding

0.79	GO:0008305	integrin complex
0.62	GO:0032587	ruffle membrane
0.61	GO:0005925	focal adhesion
0.59	GO:0009897	external side of plasma membrane
0.55	GO:0005911	cell-cell junction
0.54	GO:0045202	synapse
0.53	GO:0031410	cytoplasmic vesicle
0.52	GO:0005794	Golgi apparatus
0.52	GO:0005783	endoplasmic reticulum
0.44	GO:0035868	alphav-beta3 integrin-HMGB1 complex

sp|P08651|NFIC_HUMAN
Nuclear factor 1 C-type
Search

NFIC

0.79	Nuclear factor 1 C-type

0.65	GO:0006260	DNA replication
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.48	GO:0042475	odontogenesis of dentin-containing tooth
0.47	GO:0051254	positive regulation of RNA metabolic process
0.47	GO:0010557	positive regulation of macromolecule biosynthetic process
0.47	GO:0031328	positive regulation of cellular biosynthetic process
0.46	GO:0051253	negative regulation of RNA metabolic process

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P08670|VIME_HUMAN
Vimentin
Search

VIM

0.85	Putative nuclear envelope protein lamin intermediate filament superfamily

0.59	GO:0060020	Bergmann glial cell differentiation
0.58	GO:0070307	lens fiber cell development
0.58	GO:0010714	positive regulation of collagen metabolic process
0.58	GO:0032965	regulation of collagen biosynthetic process
0.58	GO:0014002	astrocyte development
0.57	GO:0045109	intermediate filament organization
0.56	GO:0060395	SMAD protein signal transduction
0.56	GO:0071346	cellular response to interferon-gamma
0.56	GO:0010977	negative regulation of neuron projection development
0.55	GO:0043488	regulation of mRNA stability

0.62	GO:0005198	structural molecule activity
0.60	GO:1990254	keratin filament binding
0.57	GO:0097110	scaffold protein binding
0.55	GO:0008022	protein C-terminus binding
0.52	GO:0019904	protein domain specific binding
0.52	GO:0003725	double-stranded RNA binding
0.51	GO:0042802	identical protein binding
0.35	GO:0051721	protein phosphatase 2A binding
0.34	GO:0019901	protein kinase binding

0.79	GO:0005882	intermediate filament
0.55	GO:0045335	phagocytic vesicle
0.55	GO:0005844	polysome
0.54	GO:0031252	cell leading edge
0.52	GO:0043005	neuron projection
0.52	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

sp|P08684|CP3A4_HUMAN
Cytochrome P450 3A4
Search

0.97	Cytochrome P450 family 3 subfamily A polypeptide 4

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0009822	alkaloid catabolic process
0.49	GO:0002933	lipid hydroxylation
0.47	GO:0008202	steroid metabolic process
0.45	GO:0070988	demethylation
0.43	GO:0042445	hormone metabolic process
0.42	GO:0016098	monoterpenoid metabolic process
0.42	GO:0042738	exogenous drug catabolic process
0.42	GO:0042362	fat-soluble vitamin biosynthetic process
0.41	GO:1901615	organic hydroxy compound metabolic process

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.52	GO:0008395	steroid hydroxylase activity
0.43	GO:0030343	vitamin D3 25-hydroxylase activity
0.43	GO:0034875	caffeine oxidase activity
0.42	GO:0070576	vitamin D 24-hydroxylase activity
0.40	GO:0005496	steroid binding
0.38	GO:0019899	enzyme binding
0.37	GO:0019825	oxygen binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

GO:0016712

sp|P08686|CP21A_HUMAN
Steroid 21-hydroxylase
Search

CYP21A2

0.97	Mutant 21-hydroxylase B

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0006694	steroid biosynthetic process
0.38	GO:0008212	mineralocorticoid metabolic process
0.36	GO:0042446	hormone biosynthetic process
0.36	GO:0008211	glucocorticoid metabolic process
0.35	GO:0042448	progesterone metabolic process
0.35	GO:0016125	sterol metabolic process
0.35	GO:0006956	complement activation
0.35	GO:0071375	cellular response to peptide hormone stimulus
0.34	GO:0006954	inflammatory response

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0005496	steroid binding
0.34	GO:0004866	endopeptidase inhibitor activity

0.41	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031090	organelle membrane
0.34	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P08697|A2AP_HUMAN
Alpha-2-antiplasmin
Search

SERPINF2

0.97	Alpha-2-plasmin inhibitor

0.85	GO:0051918	negative regulation of fibrinolysis
0.72	GO:0010951	negative regulation of endopeptidase activity
0.65	GO:0010757	negative regulation of plasminogen activation
0.65	GO:0002034	regulation of blood vessel diameter by renin-angiotensin
0.65	GO:0071636	positive regulation of transforming growth factor beta production
0.64	GO:0032967	positive regulation of collagen biosynthetic process
0.62	GO:0051496	positive regulation of stress fiber assembly
0.62	GO:0048661	positive regulation of smooth muscle cell proliferation
0.61	GO:0030199	collagen fibril organization
0.61	GO:0046330	positive regulation of JNK cascade

0.75	GO:0004867	serine-type endopeptidase inhibitor activity
0.61	GO:0002020	protease binding
0.56	GO:0042803	protein homodimerization activity
0.33	GO:0008233	peptidase activity
0.32	GO:0003676	nucleic acid binding

0.73	GO:0005615	extracellular space
0.56	GO:0009986	cell surface
0.47	GO:0043234	protein complex
0.40	GO:1903561	extracellular vesicle
0.38	GO:0031093	platelet alpha granule lumen
0.32	GO:0015629	actin cytoskeleton
0.32	GO:0044430	cytoskeletal part
0.30	GO:0016020	membrane

0.33

GO:0008233

sp|P08700|IL3_HUMAN
Interleukin-3
Search

IL3

0.97	Interleukin-3

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.71	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.71	GO:0035162	embryonic hemopoiesis
0.70	GO:0045740	positive regulation of DNA replication
0.54	GO:0001660	fever generation
0.50	GO:0019221	cytokine-mediated signaling pathway
0.47	GO:0008284	positive regulation of cell proliferation
0.42	GO:0000165	MAPK cascade
0.42	GO:0018108	peptidyl-tyrosine phosphorylation

0.88	GO:0005135	interleukin-3 receptor binding
0.78	GO:0008083	growth factor activity
0.77	GO:0005125	cytokine activity
0.53	GO:0005149	interleukin-1 receptor binding
0.42	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.42	GO:0004713	protein tyrosine kinase activity

0.71	GO:0005615	extracellular space
0.34	GO:0005622	intracellular

0.42

GO:0004713

sp|P08708|RS17_HUMAN
40S ribosomal protein S17
Search

RPS17

0.70	Ribosomal protein S17

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000028	ribosomal small subunit assembly
0.47	GO:0034101	erythrocyte homeostasis
0.42	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0045182	translation regulator activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

sp|P08709|FA7_HUMAN
Coagulation factor VII
Search

0.82	Coagulation factor VII

0.81	GO:0007596	blood coagulation
0.61	GO:0006508	proteolysis
0.60	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.59	GO:0050927	positive regulation of positive chemotaxis
0.57	GO:0051897	positive regulation of protein kinase B signaling
0.57	GO:0002690	positive regulation of leukocyte chemotaxis
0.50	GO:0051604	protein maturation
0.44	GO:1905217	response to astaxanthin
0.43	GO:1904400	response to Thyroid stimulating hormone
0.43	GO:1905225	response to thyrotropin-releasing hormone

0.70	GO:0005509	calcium ion binding
0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0005102	receptor binding
0.36	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0005543	phospholipid binding

0.65	GO:0005576	extracellular region
0.61	GO:1905286	serine-type peptidase complex
0.38	GO:0031982	vesicle
0.37	GO:0005796	Golgi lumen
0.36	GO:0005783	endoplasmic reticulum
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P08727|K1C19_HUMAN
Keratin, type I cytoskeletal 19
Search

KRT19

0.90	Putative nuclear envelope protein lamin intermediate filament superfamily

0.54	GO:0043627	response to estrogen
0.53	GO:0045214	sarcomere organization
0.52	GO:0060706	cell differentiation involved in embryonic placenta development
0.51	GO:0007219	Notch signaling pathway
0.48	GO:0042633	hair cycle
0.47	GO:0045103	intermediate filament-based process
0.45	GO:0030855	epithelial cell differentiation
0.44	GO:0007568	aging
0.44	GO:0043588	skin development
0.43	GO:0008544	epidermis development

0.62	GO:0005198	structural molecule activity
0.42	GO:1990254	keratin filament binding
0.40	GO:0032395	MHC class II receptor activity
0.39	GO:0042289	MHC class II protein binding
0.38	GO:0097110	scaffold protein binding
0.35	GO:0045294	alpha-catenin binding
0.34	GO:0045296	cadherin binding

0.79	GO:0005882	intermediate filament
0.55	GO:0043034	costamere
0.54	GO:1990357	terminal web
0.53	GO:0016327	apicolateral plasma membrane
0.52	GO:0042383	sarcolemma
0.52	GO:0030018	Z disc
0.41	GO:0045178	basal part of cell
0.39	GO:0070062	extracellular exosome
0.39	GO:0016010	dystrophin-associated glycoprotein complex
0.37	GO:0005634	nucleus

sp|P08729|K2C7_HUMAN
Keratin, type II cytoskeletal 7
Search

KRT7

0.92	Keratin, type II cytoskeletal cochleal

0.40	GO:0045616	regulation of keratinocyte differentiation
0.39	GO:0097284	hepatocyte apoptotic process
0.38	GO:0070268	cornification
0.38	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.38	GO:0097191	extrinsic apoptotic signaling pathway
0.36	GO:0051599	response to hydrostatic pressure
0.36	GO:0060706	cell differentiation involved in embryonic placenta development
0.36	GO:0045214	sarcomere organization
0.36	GO:0043207	response to external biotic stimulus
0.36	GO:0051704	multi-organism process

0.62	GO:0005198	structural molecule activity
0.40	GO:0097110	scaffold protein binding
0.35	GO:0032403	protein complex binding

0.83	GO:0045095	keratin filament
0.39	GO:0005737	cytoplasm
0.39	GO:0070062	extracellular exosome
0.38	GO:0016327	apicolateral plasma membrane
0.38	GO:0016363	nuclear matrix
0.38	GO:0042383	sarcolemma
0.37	GO:0005911	cell-cell junction
0.36	GO:0005654	nucleoplasm
0.35	GO:0016010	dystrophin-associated glycoprotein complex
0.33	GO:0036338	viral membrane

sp|P08754|GNAI3_HUMAN
Guanine nucleotide-binding protein G(k) subunit alpha
Search

GNAI3

0.79	Guanine nucleotide binding protein alpha inhibiting 3

0.80	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.44	GO:0007212	dopamine receptor signaling pathway
0.43	GO:1904778	positive regulation of protein localization to cell cortex
0.43	GO:0016239	positive regulation of macroautophagy
0.43	GO:1904321	response to forskolin
0.42	GO:0043949	regulation of cAMP-mediated signaling
0.42	GO:0051301	cell division
0.42	GO:0046039	GTP metabolic process
0.42	GO:1901655	cellular response to ketone
0.42	GO:0060236	regulation of mitotic spindle organization

0.79	GO:0031683	G-protein beta/gamma-subunit complex binding
0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.63	GO:0004871	signal transducer activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0031821	G-protein coupled serotonin receptor binding
0.42	GO:0032794	GTPase activating protein binding
0.38	GO:0019904	protein domain specific binding

0.47	GO:0030496	midbody
0.46	GO:0005813	centrosome
0.45	GO:1905360	GTPase complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0099738	cell cortex region
0.41	GO:0005730	nucleolus
0.41	GO:0098797	plasma membrane protein complex
0.40	GO:0000139	Golgi membrane
0.40	GO:0042588	zymogen granule
0.40	GO:0005789	endoplasmic reticulum membrane

sp|P08758|ANXA5_HUMAN
Annexin A5
Search

ANXA5

0.57

Annexin

0.84	GO:0050819	negative regulation of coagulation
0.49	GO:0010033	response to organic substance
0.41	GO:0007596	blood coagulation
0.40	GO:0032879	regulation of localization
0.39	GO:0040012	regulation of locomotion
0.37	GO:0032717	negative regulation of interleukin-8 production
0.37	GO:0048523	negative regulation of cellular process
0.37	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.36	GO:0006816	calcium ion transport
0.36	GO:0007219	Notch signaling pathway

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.38	GO:0048306	calcium-dependent protein binding
0.37	GO:0051059	NF-kappaB binding
0.36	GO:0042802	identical protein binding
0.36	GO:0035374	chondroitin sulfate binding
0.36	GO:0015085	calcium ion transmembrane transporter activity
0.35	GO:0004859	phospholipase inhibitor activity
0.35	GO:0017046	peptide hormone binding
0.35	GO:0030971	receptor tyrosine kinase binding

0.59	GO:0072563	endothelial microparticle
0.53	GO:0009897	external side of plasma membrane
0.38	GO:0031982	vesicle
0.38	GO:0005622	intracellular
0.36	GO:0005925	focal adhesion
0.36	GO:0043230	extracellular organelle
0.36	GO:0012505	endomembrane system
0.35	GO:0014704	intercalated disc
0.35	GO:0043204	perikaryon
0.35	GO:0043679	axon terminus

sp|P08779|K1C16_HUMAN
Keratin, type I cytoskeletal 16
Search

0.93	Putative nuclear envelope protein lamin intermediate filament superfamily

0.63	GO:0042633	hair cycle
0.61	GO:0045104	intermediate filament cytoskeleton organization
0.57	GO:0030855	epithelial cell differentiation
0.56	GO:0007568	aging
0.53	GO:0043588	skin development
0.53	GO:0008544	epidermis development
0.51	GO:0002009	morphogenesis of an epithelium
0.50	GO:0051546	keratinocyte migration
0.50	GO:0097435	supramolecular fiber organization
0.49	GO:0030336	negative regulation of cell migration

0.62	GO:0005198	structural molecule activity
0.52	GO:1990254	keratin filament binding
0.50	GO:0032395	MHC class II receptor activity
0.48	GO:0042289	MHC class II protein binding
0.37	GO:0097110	scaffold protein binding

0.79	GO:0005882	intermediate filament
0.50	GO:0045178	basal part of cell
0.42	GO:0005634	nucleus
0.41	GO:0071944	cell periphery
0.40	GO:0070062	extracellular exosome
0.39	GO:0005737	cytoplasm
0.36	GO:0036338	viral membrane
0.33	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

sp|P08833|IBP1_HUMAN
Insulin-like growth factor-binding protein 1
Search

IGFBP1

0.97	Insulin like growth factor binding protein 1

0.76	GO:0001558	regulation of cell growth
0.51	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.43	GO:0031099	regeneration
0.40	GO:0008286	insulin receptor signaling pathway
0.40	GO:0045927	positive regulation of growth
0.39	GO:0040007	growth
0.39	GO:0007568	aging
0.39	GO:0042060	wound healing
0.39	GO:0008285	negative regulation of cell proliferation
0.39	GO:0001666	response to hypoxia

0.84	GO:0005520	insulin-like growth factor binding
0.35	GO:0005102	receptor binding
0.33	GO:0035718	macrophage migration inhibitory factor binding
0.33	GO:0023026	MHC class II protein complex binding
0.33	GO:0050998	nitric-oxide synthase binding
0.32	GO:0001540	amyloid-beta binding
0.32	GO:0044183	protein binding involved in protein folding
0.32	GO:0004896	cytokine receptor activity

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.37	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0035693	NOS2-CD74 complex
0.33	GO:0035692	macrophage migration inhibitory factor receptor complex
0.32	GO:0031982	vesicle
0.32	GO:0009897	external side of plasma membrane
0.32	GO:0005764	lysosome
0.32	GO:0042613	MHC class II protein complex
0.30	GO:0016021	integral component of membrane

sp|P08842|STS_HUMAN
Steryl-sulfatase
Search

STS

0.96	Steroid sulfatase

0.38	GO:0007565	female pregnancy
0.38	GO:0006687	glycosphingolipid metabolic process
0.37	GO:0043687	post-translational protein modification
0.37	GO:0008202	steroid metabolic process
0.36	GO:0048856	anatomical structure development
0.35	GO:0043627	response to estrogen
0.34	GO:0009268	response to pH
0.34	GO:0016042	lipid catabolic process
0.34	GO:0007611	learning or memory
0.34	GO:0043434	response to peptide hormone

0.74	GO:0008484	sulfuric ester hydrolase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.38	GO:0012505	endomembrane system
0.37	GO:0031984	organelle subcompartment
0.36	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0044444	cytoplasmic part
0.35	GO:0043233	organelle lumen
0.35	GO:0031982	vesicle
0.34	GO:0043230	extracellular organelle
0.34	GO:0031090	organelle membrane
0.33	GO:0005615	extracellular space
0.33	GO:0005886	plasma membrane

0.74

EC:3.1.6

GO:0008484

sp|P08861|CEL3B_HUMAN
Chymotrypsin-like elastase family member 3B
Search

0.81	Pancreatic elastase

0.61	GO:0006508	proteolysis
0.47	GO:0008203	cholesterol metabolic process
0.39	GO:0061436	establishment of skin barrier
0.37	GO:0007586	digestion
0.34	GO:0070268	cornification
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0007596	blood coagulation
0.33	GO:0010468	regulation of gene expression

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.47	GO:0005615	extracellular space
0.38	GO:0036457	keratohyalin granule
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P08865|RSSA_HUMAN
40S ribosomal protein SA
Search

RPSA

0.73	40S ribosomal protein SA

0.77	GO:0000028	ribosomal small subunit assembly
0.65	GO:0007155	cell adhesion
0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.47	GO:0006407	rRNA export from nucleus
0.42	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0016072	rRNA metabolic process
0.37	GO:0030855	epithelial cell differentiation

0.84	GO:0005055	laminin receptor activity
0.79	GO:0043236	laminin binding
0.61	GO:0003735	structural constituent of ribosome
0.38	GO:0001618	virus receptor activity
0.36	GO:0043022	ribosome binding
0.33	GO:0003723	RNA binding

0.73	GO:0022627	cytosolic small ribosomal subunit
0.57	GO:0005634	nucleus
0.52	GO:0005886	plasma membrane
0.45	GO:0030686	90S preribosome
0.37	GO:0005604	basement membrane
0.37	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.33	GO:0043233	organelle lumen

sp|P08887|IL6RA_HUMAN
Interleukin-6 receptor subunit alpha
Search

IL6R

0.97	Interleukin-6 receptor subunit alpha

0.79	GO:0019221	cytokine-mediated signaling pathway
0.68	GO:0071354	cellular response to interleukin-6
0.67	GO:0048661	positive regulation of smooth muscle cell proliferation
0.67	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.66	GO:0031018	endocrine pancreas development
0.66	GO:0032722	positive regulation of chemokine production
0.66	GO:0032755	positive regulation of interleukin-6 production
0.45	GO:0032966	negative regulation of collagen biosynthetic process
0.45	GO:0010536	positive regulation of activation of Janus kinase activity
0.42	GO:0043410	positive regulation of MAPK cascade

0.81	GO:0004896	cytokine receptor activity
0.73	GO:0070119	ciliary neurotrophic factor binding
0.71	GO:0019981	interleukin-6 binding
0.68	GO:0005138	interleukin-6 receptor binding
0.59	GO:0042803	protein homodimerization activity
0.56	GO:0019899	enzyme binding
0.33	GO:0004012	phospholipid-translocating ATPase activity
0.32	GO:0000287	magnesium ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.70	GO:0005896	interleukin-6 receptor complex
0.70	GO:0070110	ciliary neurotrophic factor receptor complex
0.63	GO:0016324	apical plasma membrane
0.53	GO:0005576	extracellular region
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0009986	cell surface
0.37	GO:0032809	neuronal cell body membrane

0.33

EC:3.6.3.1

GO:0004012

sp|P08908|5HT1A_HUMAN
5-hydroxytryptamine receptor 1A
Search

HTR1A

0.93	5-hydroxytryptamine receptor

0.84	GO:0042310	vasoconstriction
0.84	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.83	GO:0050795	regulation of behavior
0.81	GO:0046883	regulation of hormone secretion
0.79	GO:0008283	cell proliferation
0.64	GO:0014062	regulation of serotonin secretion
0.62	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.62	GO:0042053	regulation of dopamine metabolic process
0.61	GO:0042428	serotonin metabolic process
0.61	GO:0035640	exploration behavior

0.84	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.63	GO:0090722	receptor-receptor interaction
0.51	GO:0051378	serotonin binding
0.35	GO:0001965	G-protein alpha-subunit binding
0.32	GO:0008144	drug binding

0.66	GO:0005887	integral component of plasma membrane
0.36	GO:0043203	axon hillock
0.31	GO:0005622	intracellular

sp|P08910|ABHD2_HUMAN
Monoacylglycerol lipase ABHD2
Search

ABHD2

0.96	Abhydrolase domain-containing protein 2

0.60	GO:0048240	sperm capacitation
0.60	GO:0046464	acylglycerol catabolic process
0.58	GO:0032570	response to progesterone
0.58	GO:0007340	acrosome reaction
0.56	GO:0030336	negative regulation of cell migration
0.55	GO:0043401	steroid hormone mediated signaling pathway
0.54	GO:0009611	response to wounding

0.59	GO:0047372	acylglycerol lipase activity
0.56	GO:0042562	hormone binding
0.54	GO:0003707	steroid hormone receptor activity

0.62	GO:0097524	sperm plasma membrane
0.58	GO:0036126	sperm flagellum
0.57	GO:0001669	acrosomal vesicle
0.30	GO:0016021	integral component of membrane

0.59

EC:3.1.1.23

GO:0047372

sp|P08912|ACM5_HUMAN
Muscarinic acetylcholine receptor M5
Search

CHRM5

0.81	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.84	GO:0022600	digestive system process
0.71	GO:0046717	acid secretion
0.65	GO:0015872	dopamine transport
0.64	GO:0032941	secretion by tissue
0.63	GO:0007589	body fluid secretion
0.62	GO:0019226	transmission of nerve impulse
0.56	GO:0045987	positive regulation of smooth muscle contraction
0.53	GO:0007271	synaptic transmission, cholinergic
0.52	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.40	GO:0042166	acetylcholine binding
0.36	GO:0016934	extracellularly glycine-gated chloride channel activity
0.36	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.38	GO:0043679	axon terminus
0.38	GO:0032279	asymmetric synapse
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0030425	dendrite

0.36	EC:3.1.4.11	GO:0004435
0.36	KEGG:R03435	GO:0004435

sp|P08913|ADA2A_HUMAN
Alpha-2A adrenergic receptor
Search

ADRA2A

0.76	Adrenoceptor alpha 2A

0.85	GO:0071875	adrenergic receptor signaling pathway
0.81	GO:0006940	regulation of smooth muscle contraction
0.81	GO:0019229	regulation of vasoconstriction
0.81	GO:0030168	platelet activation
0.74	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.74	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.72	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.72	GO:0050995	negative regulation of lipid catabolic process
0.71	GO:0032148	activation of protein kinase B activity
0.70	GO:0030818	negative regulation of cAMP biosynthetic process

0.85	GO:0004935	adrenergic receptor activity
0.75	GO:0031696	alpha-2C adrenergic receptor binding
0.75	GO:0032795	heterotrimeric G-protein binding
0.74	GO:0051380	norepinephrine binding
0.73	GO:0051379	epinephrine binding
0.72	GO:0031996	thioesterase binding
0.64	GO:0019901	protein kinase binding
0.61	GO:0042803	protein homodimerization activity
0.61	GO:0046982	protein heterodimerization activity

0.64	GO:0043235	receptor complex
0.56	GO:0005887	integral component of plasma membrane
0.43	GO:0005737	cytoplasm

sp|P08922|ROS1_HUMAN
Proto-oncogene tyrosine-protein kinase ROS
Search

ROS1

0.56	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.59	GO:0010966	regulation of phosphate transport
0.55	GO:0002066	columnar/cuboidal epithelial cell development
0.55	GO:0070372	regulation of ERK1 and ERK2 cascade
0.54	GO:0046777	protein autophosphorylation
0.54	GO:0007283	spermatogenesis
0.54	GO:0032006	regulation of TOR signaling
0.54	GO:0008283	cell proliferation
0.54	GO:0001558	regulation of cell growth

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0019903	protein phosphatase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0042289	MHC class II protein binding
0.35	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.33	GO:0008092	cytoskeletal protein binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0009986	cell surface
0.33	GO:0005856	cytoskeleton
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

GO:0004714

sp|P08949|NMB_HUMAN
Neuromedin-B
Search

NMB

0.97	Neuromedin Bb

0.80	GO:0007218	neuropeptide signaling pathway
0.38	GO:0010646	regulation of cell communication
0.38	GO:0023051	regulation of signaling
0.37	GO:1903531	negative regulation of secretion by cell
0.37	GO:0007267	cell-cell signaling
0.37	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0050482	arachidonic acid secretion
0.37	GO:1903532	positive regulation of secretion by cell
0.37	GO:0042593	glucose homeostasis
0.36	GO:0008284	positive regulation of cell proliferation

0.39	GO:0031710	neuromedin B receptor binding
0.38	GO:0005179	hormone activity
0.35	GO:0017171	serine hydrolase activity
0.34	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0003676	nucleic acid binding

0.39	GO:0005576	extracellular region
0.36	GO:0043005	neuron projection
0.30	GO:0016020	membrane

sp|P08962|CD63_HUMAN
CD63 antigen
Search

CD63

0.59	Tetraspanin

0.45	GO:0035188	hatching
0.44	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.43	GO:0050931	pigment cell differentiation
0.43	GO:0045807	positive regulation of endocytosis
0.42	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.42	GO:0043482	cellular pigment accumulation
0.42	GO:0002090	regulation of receptor internalization
0.42	GO:0016477	cell migration
0.41	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0007160	cell-matrix adhesion

0.43	GO:0097487	multivesicular body, internal vesicle
0.42	GO:0032585	multivesicular body membrane
0.42	GO:0005764	lysosome
0.41	GO:0042470	melanosome
0.41	GO:0031226	intrinsic component of plasma membrane
0.40	GO:0070062	extracellular exosome
0.40	GO:0098852	lytic vacuole membrane
0.39	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P08F94|PKHD1_HUMAN
Fibrocystin
Search

PKHD1

0.92	Polycystic kidney and hepatic disease 1

0.85	GO:0010824	regulation of centrosome duplication
0.67	GO:0051898	negative regulation of protein kinase B signaling
0.66	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.64	GO:0070372	regulation of ERK1 and ERK2 cascade
0.63	GO:0001822	kidney development
0.63	GO:0006874	cellular calcium ion homeostasis
0.62	GO:0032006	regulation of TOR signaling
0.62	GO:0008284	positive regulation of cell proliferation
0.61	GO:0060271	cilium assembly
0.61	GO:0043066	negative regulation of apoptotic process

0.40	GO:0005515	protein binding
0.32	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0003743	translation initiation factor activity
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding
0.32	GO:0005044	scavenger receptor activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0005509	calcium ion binding

0.64	GO:0036064	ciliary basal body
0.64	GO:0016324	apical plasma membrane
0.63	GO:0072686	mitotic spindle
0.62	GO:0048471	perinuclear region of cytoplasm
0.61	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0005615	extracellular space
0.30	GO:0009986	cell surface
0.30	GO:0098687	chromosomal region

0.32

GO:0004714

sp|P09001|RM03_HUMAN
39S ribosomal protein L3, mitochondrial
Search

MRPL3

0.97	Mitochondrial ribosomal protein L3

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.52	GO:0005759	mitochondrial matrix
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P09012|SNRPA_HUMAN
U1 small nuclear ribonucleoprotein A
Search

SNRPA

0.90	Small nuclear ribonucleoprotein polypeptide A

0.47	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:1900363	regulation of mRNA polyadenylation

0.58	GO:0003723	RNA binding
0.51	GO:0042802	identical protein binding
0.40	GO:1990446	U1 snRNP binding

0.60	GO:0019013	viral nucleocapsid
0.57	GO:0005685	U1 snRNP
0.53	GO:0005681	spliceosomal complex
0.50	GO:0005654	nucleoplasm
0.34	GO:0001650	fibrillar center
0.34	GO:0005686	U2 snRNP
0.33	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

sp|P09016|HXD4_HUMAN
Homeobox protein Hox-D4
Search

HOXD4

0.97	Homeobox protein Hox-D4

0.66	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0048863	stem cell differentiation
0.52	GO:0006366	transcription by RNA polymerase II
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.51	GO:0009653	anatomical structure morphogenesis
0.33	GO:0002376	immune system process

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0030054	cell junction
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

sp|P09017|HXC4_HUMAN
Homeobox protein Hox-C4
Search

HOXC4

0.96	Homeobox protein Hox-C4

0.67	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0061448	connective tissue development
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process
0.47	GO:0009653	anatomical structure morphogenesis

0.61	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0071837	HMG box domain binding
0.53	GO:0035326	enhancer binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding

0.60	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P09038|FGF2_HUMAN
Fibroblast growth factor 2
Search

FGF2

0.45	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.55	GO:0014843	growth factor dependent regulation of skeletal muscle satellite cell proliferation
0.55	GO:0001525	angiogenesis
0.54	GO:0045766	positive regulation of angiogenesis
0.54	GO:0060128	corticotropin hormone secreting cell differentiation
0.54	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation
0.54	GO:0021762	substantia nigra development
0.53	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation
0.53	GO:0046668	regulation of retinal cell programmed cell death

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.49	GO:0008201	heparin binding
0.41	GO:0090722	receptor-receptor interaction
0.40	GO:0042056	chemoattractant activity
0.40	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.39	GO:0005125	cytokine activity
0.38	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.66	GO:0005576	extracellular region
0.41	GO:0005634	nucleus
0.38	GO:0005938	cell cortex
0.38	GO:0005829	cytosol
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part

0.38	EC:2.7.1.153	GO:0046934
0.38	KEGG:R04545	GO:0046934

sp|P09067|HXB5_HUMAN
Homeobox protein Hox-B5
Search

HOXB5

0.87	Homeobox protein Hox-B5

0.68	GO:0007275	multicellular organism development
0.57	GO:0030855	epithelial cell differentiation
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0003158	endothelium development
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0009653	anatomical structure morphogenesis
0.51	GO:0010870	positive regulation of receptor biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0035326	enhancer binding
0.53	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part

sp|P09086|PO2F2_HUMAN
POU domain, class 2, transcription factor 2
Search

POU2F2

0.56	POU domain, class 2, transcription factor 2

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0002380	immunoglobulin secretion involved in immune response
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0002335	mature B cell differentiation
0.51	GO:0048469	cell maturation
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.49	GO:0019904	protein domain specific binding
0.35	GO:0001223	transcription coactivator binding
0.34	GO:0035326	enhancer binding
0.33	GO:0046983	protein dimerization activity

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.33	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P09093|CEL3A_HUMAN
Chymotrypsin-like elastase family member 3A
Search

0.88	Pancreatic elastase

0.61	GO:0006508	proteolysis
0.47	GO:0008203	cholesterol metabolic process
0.38	GO:0032501	multicellular organismal process
0.38	GO:0050878	regulation of body fluid levels
0.36	GO:0042060	wound healing
0.36	GO:0030104	water homeostasis
0.35	GO:0048856	anatomical structure development
0.34	GO:0012501	programmed cell death
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.47	GO:0005615	extracellular space
0.38	GO:0036457	keratohyalin granule
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P09104|ENOG_HUMAN
Gamma-enolase
Search

ENO2

0.93	Neuron-specific enolase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0046496	nicotinamide nucleotide metabolic process
0.36	GO:0043403	skeletal muscle tissue regeneration
0.36	GO:0019319	hexose biosynthetic process
0.36	GO:0006006	glucose metabolic process
0.35	GO:0007568	aging
0.35	GO:0042493	response to drug
0.35	GO:0051290	protein heterotetramerization

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0019899	enzyme binding

0.77	GO:0000015	phosphopyruvate hydratase complex
0.54	GO:0001917	photoreceptor inner segment
0.53	GO:0043204	perikaryon
0.52	GO:0043209	myelin sheath
0.43	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0044448	cell cortex part
0.35	GO:0030426	growth cone
0.34	GO:0045121	membrane raft
0.34	GO:0044456	synapse part

0.78

EC:4.2.1.11

GO:0004634

sp|P09105|HBAT_HUMAN
Hemoglobin subunit theta-1
Search

HBA

0.59	Hemoglobin subunit theta

0.79	GO:0015671	oxygen transport
0.36	GO:0048821	erythrocyte development
0.36	GO:0051291	protein heterooligomerization
0.36	GO:0042542	response to hydrogen peroxide
0.36	GO:0001701	in utero embryonic development
0.35	GO:0010942	positive regulation of cell death
0.35	GO:0042744	hydrogen peroxide catabolic process
0.35	GO:0014070	response to organic cyclic compound
0.35	GO:0051930	regulation of sensory perception of pain
0.35	GO:0045776	negative regulation of blood pressure

0.79	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.37	GO:0031720	haptoglobin binding
0.35	GO:0004601	peroxidase activity
0.35	GO:0001540	amyloid-beta binding

0.82	GO:0005833	hemoglobin complex
0.37	GO:0031838	haptoglobin-hemoglobin complex
0.36	GO:0072562	blood microparticle
0.36	GO:0070062	extracellular exosome
0.36	GO:0022627	cytosolic small ribosomal subunit
0.34	GO:0043209	myelin sheath
0.34	GO:0045202	synapse
0.30	GO:0016020	membrane

0.35	EC:1.11.1.7	GO:0004601
0.35	KEGG:R03532	GO:0004601

sp|P09110|THIK_HUMAN
3-ketoacyl-CoA thiolase, peroxisomal
Search

ACAA1

0.85	Acetyl-Coenzyme A acyltransferase 1

0.71	GO:0008206	bile acid metabolic process
0.68	GO:0000038	very long-chain fatty acid metabolic process
0.63	GO:0006635	fatty acid beta-oxidation

0.76	GO:0016401	palmitoyl-CoA oxidase activity
0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.63

GO:0042579

microbody

0.76

EC:1.3.3

GO:0016401

sp|P09131|P3_HUMAN
P3 protein
Search

SLC10A3

0.97	Solute carrier family 10 (Sodium/bile acid cotransporter family), member 3

0.55	GO:0055085	transmembrane transport
0.54	GO:0032526	response to retinoic acid
0.48	GO:0015721	bile acid and bile salt transport
0.36	GO:0006098	pentose-phosphate shunt
0.36	GO:0006006	glucose metabolic process
0.33	GO:0055114	oxidation-reduction process

0.49	GO:0008508	bile acid:sodium symporter activity
0.37	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.36	GO:0050661	NADP binding

0.30

GO:0016021

integral component of membrane

0.37

EC:1.1.1.49

GO:0004345

sp|P09132|SRP19_HUMAN
Signal recognition particle 19 kDa protein
Search

SRP19

0.43	Signal recognition particle 19

0.73	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.42	GO:0065002	intracellular protein transmembrane transport
0.41	GO:0043623	cellular protein complex assembly
0.40	GO:0042493	response to drug

0.76	GO:0008312	7S RNA binding
0.41	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.74	GO:0048500	signal recognition particle
0.40	GO:0005730	nucleolus
0.34	GO:0005829	cytosol

0.32

GO:0016787

sp|P09172|DOPO_HUMAN
Dopamine beta-hydroxylase
Search

DBH

0.96	Dopamine beta-hydroxylase

0.60	GO:0042420	dopamine catabolic process
0.60	GO:0042421	norepinephrine biosynthetic process
0.59	GO:0042309	homoiothermy
0.57	GO:0042711	maternal behavior
0.57	GO:0001975	response to amphetamine
0.56	GO:0045907	positive regulation of vasoconstriction
0.56	GO:0048265	response to pain
0.56	GO:0001974	blood vessel remodeling
0.56	GO:0042596	fear response
0.56	GO:0048149	behavioral response to ethanol

0.84	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.72	GO:0005507	copper ion binding
0.40	GO:0031418	L-ascorbic acid binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0034774	secretory granule lumen
0.57	GO:0030667	secretory granule membrane
0.51	GO:0005615	extracellular space
0.51	GO:0005815	microtubule organizing center
0.48	GO:0005783	endoplasmic reticulum
0.43	GO:0042583	chromaffin granule
0.40	GO:0030658	transport vesicle membrane
0.36	GO:0043005	neuron projection
0.34	GO:0043025	neuronal cell body
0.34	GO:0045177	apical part of cell

0.84

EC:1.14.17

GO:0016715

sp|P09210|GSTA2_HUMAN
Glutathione S-transferase A2
Search

0.42	Glutathione S-transferase alpha I

0.47	GO:0006749	glutathione metabolic process
0.45	GO:0043651	linoleic acid metabolic process
0.45	GO:0060429	epithelium development
0.44	GO:0046222	aflatoxin metabolic process
0.43	GO:0042221	response to chemical
0.42	GO:0030154	cell differentiation
0.41	GO:1901377	organic heteropentacyclic compound catabolic process
0.40	GO:1901685	glutathione derivative metabolic process
0.39	GO:0001823	mesonephros development
0.38	GO:0035295	tube development

0.76	GO:0004364	glutathione transferase activity
0.42	GO:0004602	glutathione peroxidase activity
0.38	GO:0043295	glutathione binding
0.34	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.47	GO:0005829	cytosol
0.41	GO:0070062	extracellular exosome
0.38	GO:0005640	nuclear outer membrane

0.76

GO:0004364

sp|P09211|GSTP1_HUMAN
Glutathione S-transferase P
Search

GSTP1

0.69	Pi-class glutathione S-transferase

0.57	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
0.56	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.55	GO:0043508	negative regulation of JUN kinase activity
0.55	GO:0032691	negative regulation of interleukin-1 beta production
0.55	GO:0043651	linoleic acid metabolic process
0.54	GO:0032720	negative regulation of tumor necrosis factor production
0.53	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.51	GO:0071466	cellular response to xenobiotic stimulus
0.50	GO:0006749	glutathione metabolic process

0.77	GO:0004364	glutathione transferase activity
0.59	GO:0035730	S-nitrosoglutathione binding
0.52	GO:0035731	dinitrosyl-iron complex binding
0.51	GO:0004602	glutathione peroxidase activity
0.41	GO:0008432	JUN kinase binding
0.39	GO:0019207	kinase regulator activity
0.39	GO:0043295	glutathione binding
0.37	GO:0070026	nitric oxide binding
0.35	GO:0008144	drug binding

0.58	GO:0097057	TRAF2-GSTP1 complex
0.47	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.41	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.37	GO:1904813	ficolin-1-rich granule lumen
0.37	GO:0034774	secretory granule lumen
0.35	GO:0005886	plasma membrane

0.77

GO:0004364

sp|P09228|CYTT_HUMAN
Cystatin-SA
Search

0.72	Cystatin-SA

0.76	GO:0010951	negative regulation of endopeptidase activity
0.56	GO:2000116	regulation of cysteine-type endopeptidase activity
0.51	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.39	GO:0001895	retina homeostasis
0.39	GO:0010711	negative regulation of collagen catabolic process
0.39	GO:0060311	negative regulation of elastin catabolic process
0.38	GO:0060313	negative regulation of blood vessel remodeling
0.38	GO:0010716	negative regulation of extracellular matrix disassembly
0.36	GO:0097435	supramolecular fiber organization
0.36	GO:0006952	defense response

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.57	GO:0002020	protease binding
0.37	GO:0001540	amyloid-beta binding
0.36	GO:0042802	identical protein binding

0.54	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

sp|P09234|RU1C_HUMAN
U1 small nuclear ribonucleoprotein C
Search

SNRPC

0.74	Small nuclear ribonucleoprotein polypeptide C variant (Fragment)

0.80	GO:0000387	spliceosomal snRNP assembly
0.79	GO:0000395	mRNA 5'-splice site recognition
0.41	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.76	GO:0030619	U1 snRNA binding
0.67	GO:0003729	mRNA binding
0.62	GO:0008270	zinc ion binding
0.51	GO:0003727	single-stranded RNA binding
0.50	GO:0030627	pre-mRNA 5'-splice site binding
0.49	GO:0042803	protein homodimerization activity
0.39	GO:1990446	U1 snRNP binding
0.32	GO:0003677	DNA binding

0.80	GO:0005685	U1 snRNP
0.77	GO:0000243	commitment complex
0.75	GO:0071010	prespliceosome
0.57	GO:0019013	viral nucleocapsid
0.53	GO:0015030	Cajal body

sp|P09237|MMP7_HUMAN
Matrilysin
Search

MMP7

0.68	Macrophage metalloelastase

0.61	GO:0006508	proteolysis
0.51	GO:0022617	extracellular matrix disassembly
0.50	GO:0030574	collagen catabolic process
0.50	GO:0097186	amelogenesis
0.44	GO:0032461	positive regulation of protein oligomerization
0.43	GO:0030163	protein catabolic process
0.40	GO:0044849	estrous cycle
0.39	GO:0060135	maternal process involved in female pregnancy
0.39	GO:0071260	cellular response to mechanical stimulus
0.38	GO:0002779	antibacterial peptide secretion

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.38	GO:0008201	heparin binding
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005518	collagen binding
0.35	GO:0001047	core promoter binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0043565	sequence-specific DNA binding

0.74	GO:0031012	extracellular matrix
0.39	GO:0005615	extracellular space
0.37	GO:0005581	collagen trimer
0.37	GO:0009986	cell surface
0.37	GO:1903561	extracellular vesicle
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.70

GO:0004222

sp|P09238|MMP10_HUMAN
Stromelysin-2
Search

MMP3

0.70	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.60	GO:0030574	collagen catabolic process
0.56	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.54	GO:0032461	positive regulation of protein oligomerization
0.49	GO:0022617	extracellular matrix disassembly
0.49	GO:0030334	regulation of cell migration
0.48	GO:0003417	growth plate cartilage development
0.47	GO:0001958	endochondral ossification
0.47	GO:0030282	bone mineralization
0.39	GO:1903209	positive regulation of oxidative stress-induced cell death

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.46	GO:0005518	collagen binding
0.42	GO:0005509	calcium ion binding
0.38	GO:0004252	serine-type endopeptidase activity
0.34	GO:0001968	fibronectin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.39	GO:0005615	extracellular space
0.38	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.35	GO:0005829	cytosol
0.35	GO:0005581	collagen trimer
0.35	GO:0046581	intercellular canaliculus
0.35	GO:0030425	dendrite
0.35	GO:0044297	cell body
0.34	GO:0005739	mitochondrion
0.34	GO:0005764	lysosome

0.70

GO:0004222

sp|P09326|CD48_HUMAN
CD48 antigen
Search

sp|P09327|VILI_HUMAN
Villin-1
Search

VIL1

0.95

Adseverin

0.76	GO:0051014	actin filament severing
0.74	GO:0051693	actin filament capping
0.72	GO:0045010	actin nucleation
0.61	GO:0031346	positive regulation of cell projection organization
0.60	GO:0060327	cytoplasmic actin-based contraction involved in cell motility
0.60	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.59	GO:1902896	terminal web assembly
0.59	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.59	GO:0001951	intestinal D-glucose absorption
0.58	GO:0051240	positive regulation of multicellular organismal process

0.78	GO:0051015	actin filament binding
0.76	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.63	GO:0005509	calcium ion binding
0.60	GO:0035727	lysophosphatidic acid binding
0.58	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.52	GO:0042803	protein homodimerization activity
0.33	GO:0016791	phosphatase activity

0.58	GO:0032433	filopodium tip
0.57	GO:0005902	microvillus
0.56	GO:0032432	actin filament bundle
0.56	GO:0001726	ruffle
0.55	GO:0030027	lamellipodium
0.55	GO:0005903	brush border
0.42	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0030424	axon
0.35	GO:0005737	cytoplasm

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|P09341|GROA_HUMAN
Growth-regulated alpha protein
Search

0.88	C-X-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.72	GO:0006952	defense response
0.54	GO:0090023	positive regulation of neutrophil chemotaxis
0.52	GO:0002237	response to molecule of bacterial origin
0.52	GO:0070098	chemokine-mediated signaling pathway
0.50	GO:0050900	leukocyte migration
0.50	GO:0042127	regulation of cell proliferation
0.49	GO:0033993	response to lipid

0.84	GO:0008009	chemokine activity
0.56	GO:0045236	CXCR chemokine receptor binding
0.45	GO:0008201	heparin binding
0.41	GO:0008083	growth factor activity
0.35	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.34	GO:0008047	enzyme activator activity
0.33	GO:0005355	glucose transmembrane transporter activity
0.32	GO:0016787	hydrolase activity

0.71	GO:0005615	extracellular space
0.40	GO:0097679	other organism cytoplasm
0.39	GO:0020005	symbiont-containing vacuole membrane
0.37	GO:0034774	secretory granule lumen
0.37	GO:1904724	tertiary granule lumen
0.35	GO:0042581	specific granule
0.35	GO:0031091	platelet alpha granule
0.30	GO:0016020	membrane

0.35	EC:1.5.1.5	GO:0004488
0.35	KEGG:R01220	GO:0004488

sp|P09382|LEG1_HUMAN
Galectin-1
Search

LGALS1

0.63

Galectin

0.54	GO:0002317	plasma cell differentiation
0.54	GO:0046598	positive regulation of viral entry into host cell
0.53	GO:0031295	T cell costimulation
0.52	GO:0045445	myoblast differentiation
0.42	GO:0006915	apoptotic process
0.40	GO:0034120	positive regulation of erythrocyte aggregation
0.40	GO:0035900	response to isolation stress
0.38	GO:0048678	response to axon injury
0.38	GO:0010812	negative regulation of cell-substrate adhesion
0.38	GO:0071333	cellular response to glucose stimulus

0.70	GO:0030246	carbohydrate binding
0.40	GO:0043236	laminin binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0019863	IgE binding
0.35	GO:0042056	chemoattractant activity
0.34	GO:0004871	signal transducer activity
0.34	GO:0003723	RNA binding
0.32	GO:0036094	small molecule binding

0.50	GO:0031012	extracellular matrix
0.47	GO:0005615	extracellular space
0.37	GO:0009986	cell surface
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005622	intracellular
0.35	GO:0001772	immunological synapse
0.34	GO:0044422	organelle part
0.34	GO:0012505	endomembrane system
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0031975	envelope

sp|P09417|DHPR_HUMAN
Dihydropteridine reductase
Search

QDPR

0.64	Quinoid dihydropteridine reductase a

0.51	GO:0055114	oxidation-reduction process
0.41	GO:0010288	response to lead ion
0.41	GO:0010044	response to aluminum ion
0.41	GO:0046146	tetrahydrobiopterin metabolic process
0.41	GO:0034312	diol biosynthetic process
0.41	GO:0033762	response to glucagon
0.40	GO:0001889	liver development
0.39	GO:0042559	pteridine-containing compound biosynthetic process
0.39	GO:0035690	cellular response to drug
0.39	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process

0.53	GO:0016491	oxidoreductase activity
0.41	GO:0070404	NADH binding
0.39	GO:0070402	NADPH binding
0.38	GO:0042803	protein homodimerization activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0008234	cysteine-type peptidase activity

0.45	GO:0005739	mitochondrion
0.38	GO:0043005	neuron projection
0.37	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.53

GO:0016491

sp|P09429|HMGB1_HUMAN
High mobility group protein B1
Search

HMGB1

0.82	High mobility group box 1

0.57	GO:0032392	DNA geometric change
0.57	GO:0051103	DNA ligation involved in DNA repair
0.52	GO:0097350	neutrophil clearance
0.52	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.51	GO:0002643	regulation of tolerance induction
0.51	GO:1990774	tumor necrosis factor secretion
0.51	GO:0032072	regulation of restriction endodeoxyribonuclease activity
0.51	GO:0050716	positive regulation of interleukin-1 secretion
0.51	GO:0035711	T-helper 1 cell activation
0.50	GO:0032425	positive regulation of mismatch repair

0.72	GO:0097100	supercoiled DNA binding
0.71	GO:0000405	bubble DNA binding
0.69	GO:0008301	DNA binding, bending
0.68	GO:0000400	four-way junction DNA binding
0.49	GO:0019958	C-X-C chemokine binding
0.49	GO:0001786	phosphatidylserine binding
0.49	GO:0070182	DNA polymerase binding
0.48	GO:0070491	repressing transcription factor binding
0.47	GO:0005178	integrin binding
0.46	GO:0001530	lipopolysaccharide binding

0.58	GO:0005634	nucleus
0.50	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.47	GO:0005694	chromosome
0.46	GO:0017053	transcriptional repressor complex
0.46	GO:0005768	endosome
0.45	GO:0005615	extracellular space
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.44	GO:0009986	cell surface
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0043005	neuron projection

0.40

EC:4

GO:0016829

sp|P09430|STP1_HUMAN
Spermatid nuclear transition protein 1
Search

TNP1

0.97	Spermatid nuclear transition protein 1

0.80	GO:0007283	spermatogenesis
0.75	GO:0000012	single strand break repair
0.73	GO:0031498	chromatin disassembly
0.73	GO:0032986	protein-DNA complex disassembly
0.72	GO:0010954	positive regulation of protein processing
0.72	GO:0030317	flagellated sperm motility
0.70	GO:0006997	nucleus organization
0.69	GO:0006342	chromatin silencing
0.69	GO:0043486	histone exchange
0.69	GO:0007281	germ cell development

0.55	GO:0003677	DNA binding
0.35	GO:0005515	protein binding

0.75	GO:0000786	nucleosome
0.63	GO:0000790	nuclear chromatin
0.57	GO:0001673	male germ cell nucleus

sp|P09455|RET1_HUMAN
Retinol-binding protein 1
Search

RBP1

0.97	Nicotinamide nucleotide adenylyltransferase 3

0.84	GO:0006776	vitamin A metabolic process
0.82	GO:0002138	retinoic acid biosynthetic process
0.55	GO:0033189	response to vitamin A
0.53	GO:0030852	regulation of granulocyte differentiation
0.52	GO:0042572	retinol metabolic process
0.38	GO:0055088	lipid homeostasis
0.35	GO:0009435	NAD biosynthetic process
0.34	GO:0009611	response to wounding
0.32	GO:0016310	phosphorylation

0.72	GO:0008289	lipid binding
0.42	GO:0019842	vitamin binding
0.41	GO:0043178	alcohol binding
0.37	GO:0016779	nucleotidyltransferase activity
0.32	GO:0005515	protein binding
0.32	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0005829	cytosol
0.51	GO:0005811	lipid droplet
0.46	GO:0005654	nucleoplasm
0.38	GO:0044297	cell body
0.33	GO:0070062	extracellular exosome
0.32	GO:0005739	mitochondrion

0.37

EC:2.7.7

GO:0016779

sp|P09466|PAEP_HUMAN
Glycodelin
Search

PAEP

0.95	Beta lactoglobulin II

0.60	GO:1902491	negative regulation of sperm capacitation
0.57	GO:2000359	regulation of binding of sperm to zona pellucida
0.57	GO:2000667	positive regulation of interleukin-13 secretion
0.56	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production
0.56	GO:2000778	positive regulation of interleukin-6 secretion
0.50	GO:0006915	apoptotic process
0.37	GO:0007275	multicellular organism development

0.51	GO:0036094	small molecule binding
0.47	GO:0005501	retinoid binding
0.36	GO:0005515	protein binding

0.50

GO:0005576

extracellular region

sp|P09467|F16P1_HUMAN
Fructose-1,6-bisphosphatase 1
Search

FBP1

0.52	Acipenser baerii fructose 1,6-bisphosphatase mRNA

0.68	GO:0016311	dephosphorylation
0.60	GO:0005975	carbohydrate metabolic process
0.58	GO:0071286	cellular response to magnesium ion
0.57	GO:0045820	negative regulation of glycolytic process
0.55	GO:0006002	fructose 6-phosphate metabolic process
0.55	GO:0051289	protein homotetramerization
0.54	GO:0006111	regulation of gluconeogenesis
0.54	GO:0046580	negative regulation of Ras protein signal transduction
0.54	GO:0030308	negative regulation of cell growth
0.53	GO:0035690	cellular response to drug

0.79	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity
0.54	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.53	GO:0042802	identical protein binding
0.52	GO:0016208	AMP binding
0.42	GO:0048029	monosaccharide binding
0.41	GO:0046872	metal ion binding
0.35	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity

0.46	GO:0005634	nucleus
0.46	GO:0005829	cytosol
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0030018	Z disc
0.35	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.79

EC:3.1.3.11

GO:0042132

sp|P09471|GNAO_HUMAN
Guanine nucleotide-binding protein G(o) subunit alpha
Search

GNAO1

0.78	Guanine nucleotide binding protein alpha O

0.79	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.44	GO:0007212	dopamine receptor signaling pathway
0.40	GO:0008016	regulation of heart contraction
0.40	GO:0007626	locomotory behavior
0.39	GO:0043278	response to morphine
0.39	GO:0051926	negative regulation of calcium ion transport
0.39	GO:0042542	response to hydrogen peroxide
0.38	GO:0030900	forebrain development
0.38	GO:0007568	aging
0.38	GO:0031175	neuron projection development

0.79	GO:0031683	G-protein beta/gamma-subunit complex binding
0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.62	GO:0004871	signal transducer activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0031852	mu-type opioid receptor binding
0.45	GO:0051430	corticotropin-releasing hormone receptor 1 binding
0.45	GO:0031821	G-protein coupled serotonin receptor binding

0.42	GO:1905360	GTPase complex
0.42	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0043209	myelin sheath
0.40	GO:0030425	dendrite
0.40	GO:0044297	cell body
0.38	GO:0098797	plasma membrane protein complex

sp|P09486|SPRC_HUMAN
SPARC
Search

SPARC

0.96	Secreted protein acidic and rich in cysteine

0.61	GO:0007165	signal transduction
0.55	GO:0001501	skeletal system development
0.55	GO:0001937	negative regulation of endothelial cell proliferation
0.54	GO:0010595	positive regulation of endothelial cell migration
0.54	GO:0016525	negative regulation of angiogenesis
0.54	GO:0043473	pigmentation
0.52	GO:0048513	animal organ development
0.52	GO:0071363	cellular response to growth factor stimulus
0.47	GO:0022604	regulation of cell morphogenesis
0.44	GO:0060037	pharyngeal system development

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0005518	collagen binding
0.70	GO:0005509	calcium ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.73	GO:0005615	extracellular space
0.58	GO:0031092	platelet alpha granule membrane
0.54	GO:0016363	nuclear matrix
0.50	GO:0009986	cell surface
0.43	GO:0044420	extracellular matrix component
0.36	GO:0071682	endocytic vesicle lumen
0.35	GO:0031093	platelet alpha granule lumen
0.34	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane

sp|P09488|GSTM1_HUMAN
Glutathione S-transferase Mu 1
Search

0.42	Glutathione S-transferase

0.54	GO:0018916	nitrobenzene metabolic process
0.50	GO:0006749	glutathione metabolic process
0.48	GO:0070458	cellular detoxification of nitrogen compound
0.48	GO:0042178	xenobiotic catabolic process
0.41	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.41	GO:0071313	cellular response to caffeine
0.41	GO:0043651	linoleic acid metabolic process
0.41	GO:1901685	glutathione derivative metabolic process
0.41	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.41	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

0.78	GO:0004364	glutathione transferase activity
0.51	GO:0043295	glutathione binding
0.49	GO:0042802	identical protein binding
0.45	GO:0019899	enzyme binding
0.45	GO:0046983	protein dimerization activity
0.39	GO:0004602	glutathione peroxidase activity
0.38	GO:0005102	receptor binding
0.34	GO:0005496	steroid binding
0.34	GO:0016151	nickel cation binding

0.56	GO:0045171	intercellular bridge
0.48	GO:0005829	cytosol
0.40	GO:0016529	sarcoplasmic reticulum
0.36	GO:0043209	myelin sheath
0.34	GO:0070062	extracellular exosome
0.33	GO:0043234	protein complex

0.78

GO:0004364

sp|P09493|TPM1_HUMAN
Tropomyosin alpha-1 chain
Search

TPM1

0.86	Tropomyosin alpha-1 chain

0.74	GO:0060048	cardiac muscle contraction
0.70	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.69	GO:1904753	negative regulation of vascular associated smooth muscle cell migration
0.67	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.64	GO:0045214	sarcomere organization
0.61	GO:0003065	positive regulation of heart rate by epinephrine
0.58	GO:0034614	cellular response to reactive oxygen species
0.54	GO:0008360	regulation of cell shape
0.54	GO:0007015	actin filament organization
0.51	GO:0001701	in utero embryonic development

0.63	GO:0008307	structural constituent of muscle
0.63	GO:0008092	cytoskeletal protein binding
0.59	GO:0032403	protein complex binding
0.54	GO:0042803	protein homodimerization activity
0.54	GO:0046982	protein heterodimerization activity
0.47	GO:0097718	disordered domain specific binding
0.44	GO:0005200	structural constituent of cytoskeleton
0.42	GO:0047485	protein N-terminus binding

0.74	GO:0015629	actin cytoskeleton
0.69	GO:0032059	bleb
0.64	GO:0032587	ruffle membrane
0.62	GO:0044430	cytoskeletal part
0.62	GO:0030016	myofibril
0.61	GO:0005829	cytosol
0.59	GO:0044449	contractile fiber part
0.42	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P09496|CLCA_HUMAN
Clathrin light chain A
Search

CLTA

0.68	Clathrin light chain A

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.54	GO:0048268	clathrin coat assembly
0.45	GO:0098657	import into cell
0.38	GO:0051301	cell division
0.38	GO:0007049	cell cycle
0.37	GO:0032802	low-density lipoprotein particle receptor catabolic process
0.37	GO:0034383	low-density lipoprotein particle clearance
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0007018	microtubule-based movement

0.62	GO:0005198	structural molecule activity
0.59	GO:0032050	clathrin heavy chain binding
0.39	GO:0042277	peptide binding
0.38	GO:0032403	protein complex binding
0.38	GO:0051020	GTPase binding

0.83	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.82	GO:0030132	clathrin coat of coated pit
0.55	GO:0071439	clathrin complex
0.40	GO:0030672	synaptic vesicle membrane
0.40	GO:0099631	postsynaptic endocytic zone cytoplasmic component
0.39	GO:0005819	spindle
0.38	GO:0045334	clathrin-coated endocytic vesicle
0.37	GO:0036020	endolysosome membrane
0.37	GO:0005802	trans-Golgi network
0.36	GO:0030666	endocytic vesicle membrane

sp|P09497|CLCB_HUMAN
Clathrin light chain B
Search

CLTB

0.66	Clathrin light chain B

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.45	GO:0098657	import into cell
0.42	GO:0048268	clathrin coat assembly
0.35	GO:0036465	synaptic vesicle recycling
0.35	GO:0061024	membrane organization
0.35	GO:0097480	establishment of synaptic vesicle localization
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.35	GO:0016050	vesicle organization

0.62	GO:0005198	structural molecule activity
0.54	GO:0032050	clathrin heavy chain binding
0.39	GO:0042277	peptide binding
0.35	GO:0005326	neurotransmitter transporter activity
0.34	GO:0000287	magnesium ion binding
0.33	GO:0032403	protein complex binding
0.33	GO:0051020	GTPase binding

0.83	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.82	GO:0030132	clathrin coat of coated pit
0.56	GO:0060170	ciliary membrane
0.53	GO:0005802	trans-Golgi network
0.48	GO:0005829	cytosol
0.43	GO:0071439	clathrin complex
0.36	GO:0098793	presynapse
0.35	GO:0045334	clathrin-coated endocytic vesicle
0.34	GO:0099501	exocytic vesicle membrane
0.34	GO:0005819	spindle

sp|P09525|ANXA4_HUMAN
Annexin A4
Search

ANXA4

0.61

Annexin

0.58	GO:2000483	negative regulation of interleukin-8 secretion
0.55	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.55	GO:0007219	Notch signaling pathway
0.52	GO:0030855	epithelial cell differentiation
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0050819	negative regulation of coagulation
0.37	GO:0001778	plasma membrane repair
0.35	GO:2000145	regulation of cell motility
0.35	GO:0001822	kidney development
0.35	GO:0043066	negative regulation of apoptotic process

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.56	GO:0051059	NF-kappaB binding
0.55	GO:0048306	calcium-dependent protein binding
0.50	GO:0042802	identical protein binding
0.36	GO:0035374	chondroitin sulfate binding
0.36	GO:0004859	phospholipase inhibitor activity
0.35	GO:0008201	heparin binding
0.34	GO:0030246	carbohydrate binding
0.31	GO:0016787	hydrolase activity

0.52	GO:0031965	nuclear membrane
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0012506	vesicle membrane
0.51	GO:0009986	cell surface
0.42	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:0045177	apical part of cell
0.36	GO:0042583	chromaffin granule
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0098805	whole membrane

0.31

GO:0016787

sp|P09529|INHBB_HUMAN
Inhibin beta B chain
Search

INHBB

0.95	Inhibin beta B subunit

0.75	GO:0010469	regulation of receptor activity
0.62	GO:0032686	negative regulation of hepatocyte growth factor production
0.62	GO:0048176	regulation of hepatocyte growth factor biosynthetic process
0.62	GO:0046882	negative regulation of follicle-stimulating hormone secretion
0.61	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.60	GO:0060279	positive regulation of ovulation
0.59	GO:0032924	activin receptor signaling pathway
0.59	GO:0042036	negative regulation of cytokine biosynthetic process
0.58	GO:0046676	negative regulation of insulin secretion
0.56	GO:0045444	fat cell differentiation

0.78	GO:0008083	growth factor activity
0.77	GO:0005179	hormone activity
0.52	GO:0042803	protein homodimerization activity
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.36	GO:0034711	inhibin binding
0.35	GO:0070699	type II activin receptor binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0046812	host cell surface binding
0.34	GO:0017046	peptide hormone binding

0.66	GO:0005576	extracellular region
0.54	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0071944	cell periphery
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P09543|CN37_HUMAN
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Search

CNP

0.95	2',3'-cyclic-nucleotide 3'-phosphodiesterase

0.84	GO:0009214	cyclic nucleotide catabolic process
0.58	GO:0048709	oligodendrocyte differentiation
0.57	GO:0008344	adult locomotory behavior
0.56	GO:0061564	axon development
0.55	GO:0048667	cell morphogenesis involved in neuron differentiation
0.55	GO:0048812	neuron projection morphogenesis
0.49	GO:0009636	response to toxic substance
0.40	GO:0046902	regulation of mitochondrial membrane permeability
0.40	GO:0032496	response to lipopolysaccharide
0.40	GO:0000226	microtubule cytoskeleton organization

0.81	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
0.48	GO:0003723	RNA binding
0.39	GO:0030551	cyclic nucleotide binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005525	GTP binding
0.34	GO:0016301	kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.65	GO:0042470	melanosome
0.57	GO:0043209	myelin sheath
0.52	GO:0005615	extracellular space
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.41	GO:0031143	pseudopodium
0.40	GO:0005902	microvillus
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005741	mitochondrial outer membrane
0.38	GO:0005874	microtubule

0.81

EC:3.1.4.37

GO:0004113

sp|P09544|WNT2_HUMAN
Protein Wnt-2
Search

sp|P09564|CD7_HUMAN
T-cell antigen CD7
Search

CD7

0.89	T-cell antigen CD7

0.43	GO:0042110	T cell activation
0.43	GO:0002250	adaptive immune response
0.42	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.39	GO:0048873	homeostasis of number of cells within a tissue

0.39

GO:0004872

receptor activity

0.44	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P09565|IG2R_HUMAN
Putative insulin-like growth factor 2-associated protein
Search

0.44	Putative insulin-like growth factor 2-associated protein

0.84

GO:0005520

insulin-like growth factor binding

sp|P09601|HMOX1_HUMAN
Heme oxygenase 1
Search

HMOX1

0.58	Heme oxygenase

0.81	GO:0006788	heme oxidation
0.60	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron
0.60	GO:0072719	cellular response to cisplatin
0.60	GO:0042167	heme catabolic process
0.60	GO:0002246	wound healing involved in inflammatory response
0.59	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.59	GO:0071243	cellular response to arsenic-containing substance
0.58	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.58	GO:0048662	negative regulation of smooth muscle cell proliferation
0.58	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis

0.81	GO:0004392	heme oxygenase (decyclizing) activity
0.52	GO:0042803	protein homodimerization activity
0.47	GO:0046872	metal ion binding
0.47	GO:0020037	heme binding
0.41	GO:0004630	phospholipase D activity
0.39	GO:0019899	enzyme binding
0.36	GO:0004871	signal transducer activity

0.54	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005783	endoplasmic reticulum
0.45	GO:0005634	nucleus
0.41	GO:0005901	caveola
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.38	GO:0005829	cytosol
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005615	extracellular space

0.81

EC:1.14.99.3

GO:0004392

sp|P09603|CSF1_HUMAN
Macrophage colony-stimulating factor 1
Search

CSF1

0.97	Macrophage colony-stimulating factor 1

0.80	GO:0030316	osteoclast differentiation
0.76	GO:0010469	regulation of receptor activity
0.72	GO:0006954	inflammatory response
0.71	GO:0045087	innate immune response
0.70	GO:0060611	mammary gland fat development
0.70	GO:1902228	positive regulation of macrophage colony-stimulating factor signaling pathway
0.70	GO:1904141	positive regulation of microglial cell migration
0.68	GO:0038145	macrophage colony-stimulating factor signaling pathway
0.68	GO:0002158	osteoclast proliferation
0.68	GO:0060763	mammary duct terminal end bud growth

0.81	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.69	GO:0042803	protein homodimerization activity
0.67	GO:0005157	macrophage colony-stimulating factor receptor binding
0.33	GO:0016740	transferase activity

0.68	GO:1990682	CSF1-CSF1R complex
0.68	GO:0005615	extracellular space
0.59	GO:0048471	perinuclear region of cytoplasm
0.42	GO:1903561	extracellular vesicle
0.40	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0016740

sp|P09619|PGFRB_HUMAN
Platelet-derived growth factor receptor beta
Search

PDGFRB

0.67	Platelet-derived growth factor receptor alpha

0.76	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.59	GO:0014911	positive regulation of smooth muscle cell migration
0.59	GO:0010863	positive regulation of phospholipase C activity
0.59	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.59	GO:0006935	chemotaxis
0.58	GO:0048661	positive regulation of smooth muscle cell proliferation
0.57	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.57	GO:0007275	multicellular organism development

0.78	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.61	GO:0038085	vascular endothelial growth factor binding
0.59	GO:0048407	platelet-derived growth factor binding
0.59	GO:0005161	platelet-derived growth factor receptor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0019901	protein kinase binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.39	GO:0043548	phosphatidylinositol 3-kinase binding

0.70	GO:0043202	lysosomal lumen
0.58	GO:0031410	cytoplasmic vesicle
0.50	GO:0005794	Golgi apparatus
0.48	GO:0031226	intrinsic component of plasma membrane
0.40	GO:0016324	apical plasma membrane
0.38	GO:0009986	cell surface
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.78	EC:2.7.10.1	GO:0004714
0.36	KEGG:R04545	GO:0046934

sp|P09622|DLDH_HUMAN
Dihydrolipoyl dehydrogenase, mitochondrial
Search

DLD

0.46	Dihydrolipoyl dehydrogenase

0.68	GO:0045454	cell redox homeostasis
0.59	GO:0022900	electron transport chain
0.59	GO:0018335	protein succinylation
0.55	GO:0048240	sperm capacitation
0.52	GO:0007369	gastrulation
0.52	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.50	GO:0042391	regulation of membrane potential
0.44	GO:0006119	oxidative phosphorylation
0.43	GO:0045333	cellular respiration
0.43	GO:0060047	heart contraction

0.77	GO:0004148	dihydrolipoyl dehydrogenase activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.60	GO:0009055	electron transfer activity
0.57	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.41	GO:0043544	lipoamide binding
0.36	GO:0051287	NAD binding
0.33	GO:0005515	protein binding

0.56	GO:0043159	acrosomal matrix
0.53	GO:0045252	oxoglutarate dehydrogenase complex
0.52	GO:0043209	myelin sheath
0.52	GO:0045254	pyruvate dehydrogenase complex
0.51	GO:0005929	cilium
0.48	GO:0031974	membrane-enclosed lumen
0.46	GO:0044428	nuclear part
0.45	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.77	EC:1.8.1.4	GO:0004148
0.57	KEGG:R00209	GO:0034604

sp|P09629|HXB7_HUMAN
Homeobox protein Hox-B7
Search

HOXB7

0.97	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

0.65	GO:0007275	multicellular organism development
0.60	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0002376	immune system process
0.52	GO:0009653	anatomical structure morphogenesis
0.51	GO:0030154	cell differentiation

0.62	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P09630|HXC6_HUMAN
Homeobox protein Hox-C6
Search

HOXC6

0.97	Homeobox protein Hox-3C

0.66	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.34	GO:1902679	negative regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003714	transcription corepressor activity

0.60	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.48	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part

sp|P09651|ROA1_HUMAN
Heterogeneous nuclear ribonucleoprotein A1
Search

HNRNPA1

0.80	heterogeneous nuclear ribonucleoprotein A1

0.53	GO:1903936	cellular response to sodium arsenite
0.50	GO:0032211	negative regulation of telomere maintenance via telomerase
0.50	GO:0032212	positive regulation of telomere maintenance via telomerase
0.49	GO:0042149	cellular response to glucose starvation
0.49	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.46	GO:0051168	nuclear export
0.46	GO:0051170	nuclear import
0.40	GO:0033036	macromolecule localization
0.40	GO:0071705	nitrogen compound transport
0.40	GO:0008380	RNA splicing

0.59	GO:0003723	RNA binding
0.52	GO:0098505	G-rich strand telomeric DNA binding
0.46	GO:0019904	protein domain specific binding
0.38	GO:0042802	identical protein binding
0.34	GO:0036310	annealing helicase activity
0.33	GO:0008134	transcription factor binding

0.66	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0005654	nucleoplasm
0.41	GO:1902494	catalytic complex
0.40	GO:0030117	membrane coat
0.39	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P09661|RU2A_HUMAN
U2 small nuclear ribonucleoprotein A'
Search

SNRPA1

0.81	Small nuclear ribonucleoprotein polypeptide A'

0.47	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0035722	interleukin-12-mediated signaling pathway
0.34	GO:0006886	intracellular protein transport
0.33	GO:0006508	proteolysis

0.52	GO:0030620	U2 snRNA binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005515	protein binding

0.63	GO:0019013	viral nucleocapsid
0.60	GO:0071007	U2-type catalytic step 2 spliceosome
0.56	GO:0016607	nuclear speck
0.50	GO:0005686	U2 snRNP
0.35	GO:0030176	integral component of endoplasmic reticulum membrane

0.34

GO:0004252

sp|P09668|CATH_HUMAN
Pro-cathepsin H
Search

CTSH

0.97	Cathepsin H transcript variant 3

0.61	GO:0006508	proteolysis
0.60	GO:0010813	neuropeptide catabolic process
0.59	GO:0010815	bradykinin catabolic process
0.59	GO:0043129	surfactant homeostasis
0.58	GO:0097067	cellular response to thyroid hormone stimulus
0.58	GO:0060448	dichotomous subdivision of terminal units involved in lung branching
0.57	GO:0070371	ERK1 and ERK2 cascade
0.57	GO:0001913	T cell mediated cytotoxicity
0.57	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:0031648	protein destabilization

0.72	GO:0008234	cysteine-type peptidase activity
0.61	GO:0030108	HLA-A specific activating MHC class I receptor activity
0.60	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.58	GO:0070324	thyroid hormone binding
0.50	GO:0004177	aminopeptidase activity
0.47	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.32	GO:0030554	adenyl nucleotide binding

0.59	GO:0097208	alveolar lamellar body
0.54	GO:0005764	lysosome
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.51	GO:0005615	extracellular space
0.48	GO:0005829	cytosol
0.37	GO:1903561	extracellular vesicle
0.37	GO:0097486	multivesicular body lumen
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen

0.72

GO:0008234

sp|P09669|COX6C_HUMAN
Cytochrome c oxidase subunit 6C
Search

COX6C

0.95	Cytochrome c oxidase polypeptide VIc

0.62	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.35	GO:0006119	oxidative phosphorylation
0.35	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.51	GO:0031966	mitochondrial membrane
0.51	GO:0019866	organelle inner membrane
0.38	GO:0045277	respiratory chain complex IV
0.36	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P09681|GIP_HUMAN
Gastric inhibitory polypeptide
Search

GIP

0.97	Gastric inhibitory polypeptide

0.76	GO:0035640	exploration behavior
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0031018	endocrine pancreas development
0.74	GO:0019233	sensory perception of pain
0.73	GO:0007613	memory
0.73	GO:0008344	adult locomotory behavior
0.51	GO:0070094	positive regulation of glucagon secretion
0.49	GO:0010269	response to selenium ion
0.48	GO:0043950	positive regulation of cAMP-mediated signaling
0.48	GO:0048678	response to axon injury

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.46	GO:0043025	neuronal cell body
0.45	GO:0034774	secretory granule lumen
0.41	GO:0005788	endoplasmic reticulum lumen

sp|P09683|SECR_HUMAN
Secretin
Search

SCT

0.59

Secretin

0.76	GO:0010469	regulation of receptor activity
0.55	GO:1903640	negative regulation of gastrin-induced gastric acid secretion
0.54	GO:0090274	positive regulation of somatostatin secretion
0.54	GO:0090187	positive regulation of pancreatic juice secretion
0.52	GO:0043950	positive regulation of cAMP-mediated signaling
0.50	GO:0048566	embryonic digestive tract development
0.50	GO:0007420	brain development
0.49	GO:0030157	pancreatic juice secretion
0.47	GO:0097150	neuronal stem cell population maintenance
0.46	GO:0008542	visual learning

0.79	GO:0005179	hormone activity
0.50	GO:0047485	protein N-terminus binding

0.66

GO:0005576

extracellular region

sp|P09693|CD3G_HUMAN
T-cell surface glycoprotein CD3 gamma chain
Search

CD3G

0.97	T-cell surface glycoprotein CD3 gamma chain

0.70	GO:0007166	cell surface receptor signaling pathway
0.61	GO:0070228	regulation of lymphocyte apoptotic process
0.58	GO:0051260	protein homooligomerization
0.57	GO:0007163	establishment or maintenance of cell polarity
0.49	GO:0015031	protein transport
0.49	GO:0045059	positive thymic T cell selection
0.46	GO:0002250	adaptive immune response
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0031295	T cell costimulation
0.37	GO:0006909	phagocytosis

0.69	GO:0004888	transmembrane signaling receptor activity
0.57	GO:0046982	protein heterodimerization activity
0.57	GO:0042803	protein homodimerization activity
0.45	GO:0003713	transcription coactivator activity
0.40	GO:0042608	T cell receptor binding
0.37	GO:0030159	receptor signaling complex scaffold activity
0.35	GO:0034450	ubiquitin-ubiquitin ligase activity

0.71	GO:0042101	T cell receptor complex
0.36	GO:0030665	clathrin-coated vesicle membrane
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0000151	ubiquitin ligase complex

sp|P09758|TACD2_HUMAN
Tumor-associated calcium signal transducer 2
Search

TACSTD2

0.96	Epithelial cell adhesion molecule

0.55	GO:0007162	negative regulation of cell adhesion
0.54	GO:0001657	ureteric bud development
0.51	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
0.51	GO:1900028	negative regulation of ruffle assembly
0.50	GO:2000738	positive regulation of stem cell differentiation
0.50	GO:0042127	regulation of cell proliferation
0.50	GO:0051497	negative regulation of stress fiber assembly
0.50	GO:2000047	regulation of cell-cell adhesion mediated by cadherin
0.50	GO:0023019	signal transduction involved in regulation of gene expression
0.49	GO:0098609	cell-cell adhesion

0.45	GO:0098641	cadherin binding involved in cell-cell adhesion
0.45	GO:0032403	protein complex binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004872	receptor activity
0.34	GO:0004222	metalloendopeptidase activity
0.32	GO:0003677	DNA binding

0.57	GO:0016328	lateral plasma membrane
0.56	GO:0016323	basolateral plasma membrane
0.49	GO:0045178	basal part of cell
0.49	GO:0005923	bicellular tight junction
0.47	GO:0016324	apical plasma membrane
0.46	GO:0005615	extracellular space
0.45	GO:0009986	cell surface
0.44	GO:0005887	integral component of plasma membrane
0.41	GO:0005634	nucleus
0.39	GO:1903561	extracellular vesicle

0.34

GO:0004222

sp|P09769|FGR_HUMAN
Tyrosine-protein kinase Fgr
Search

FGR

0.57	Tyrosine-protein kinase Fyn

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.58	GO:0046777	protein autophosphorylation
0.55	GO:0032388	positive regulation of intracellular transport
0.54	GO:0050778	positive regulation of immune response
0.54	GO:0051222	positive regulation of protein transport
0.54	GO:0033005	positive regulation of mast cell activation
0.53	GO:0043302	positive regulation of leukocyte degranulation
0.53	GO:0002888	positive regulation of myeloid leukocyte mediated immunity
0.53	GO:0043304	regulation of mast cell degranulation
0.53	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0034988	Fc-gamma receptor I complex binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0001784	phosphotyrosine residue binding
0.49	GO:0019900	kinase binding
0.46	GO:0044325	ion channel binding
0.45	GO:0046875	ephrin receptor binding

0.52	GO:0016235	aggresome
0.52	GO:0032587	ruffle membrane
0.51	GO:0015629	actin cytoskeleton
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0098857	membrane microdomain
0.44	GO:0014069	postsynaptic density
0.43	GO:0005829	cytosol
0.43	GO:0030425	dendrite
0.42	GO:0005768	endosome
0.42	GO:0099513	polymeric cytoskeletal fiber

0.80	EC:2.7.10.2	GO:0004715
0.35	KEGG:R04545	GO:0046934

sp|P09848|LPH_HUMAN
Lactase-phlorizin hydrolase
Search

0.10	Lactase-phlorizin hydrolase

0.60	GO:0005975	carbohydrate metabolic process
0.30	GO:0044245	polysaccharide digestion
0.30	GO:1901657	glycosyl compound metabolic process

0.66

GO:0004553

hydrolase activity, hydrolyzing O-glycosyl compounds

0.30	GO:0098590	plasma membrane region
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0045177	apical part of cell

0.66

GO:0004553

sp|P09871|C1S_HUMAN
Complement C1s subcomponent
Search

C1S

0.85	calcium-dependent serine proteinase precursor

0.79	GO:0006958	complement activation, classical pathway
0.60	GO:0006508	proteolysis
0.55	GO:0001867	complement activation, lectin pathway
0.38	GO:0030449	regulation of complement activation
0.35	GO:0051591	response to cAMP
0.35	GO:0010001	glial cell differentiation
0.35	GO:2000258	negative regulation of protein activation cascade
0.35	GO:0002921	negative regulation of humoral immune response
0.35	GO:0010955	negative regulation of protein processing
0.34	GO:0002698	negative regulation of immune effector process

0.69	GO:0005509	calcium ion binding
0.68	GO:0004252	serine-type endopeptidase activity
0.52	GO:0042802	identical protein binding
0.41	GO:0048306	calcium-dependent protein binding
0.37	GO:0046983	protein dimerization activity
0.35	GO:0030246	carbohydrate binding
0.34	GO:0001855	complement component C4b binding

0.48	GO:0005615	extracellular space
0.38	GO:0005654	nucleoplasm
0.37	GO:1903561	extracellular vesicle
0.37	GO:0005829	cytosol
0.34	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016021	integral component of membrane

0.68

GO:0004252

sp|P09874|PARP1_HUMAN
Poly [ADP-ribose] polymerase 1
Search

PARP1

0.57	Poly [ADP-ribose] polymerase

0.83	GO:0006471	protein ADP-ribosylation
0.63	GO:1990966	ATP generation from poly-ADP-D-ribose
0.62	GO:1903518	positive regulation of single strand break repair
0.61	GO:2001170	negative regulation of ATP biosynthetic process
0.59	GO:0043504	mitochondrial DNA repair
0.57	GO:0032869	cellular response to insulin stimulus
0.57	GO:0018209	peptidyl-serine modification
0.56	GO:0034644	cellular response to UV
0.53	GO:0006915	apoptotic process
0.53	GO:0006302	double-strand break repair

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.65	GO:0051287	NAD binding
0.64	GO:1990404	protein ADP-ribosylase activity
0.62	GO:0008270	zinc ion binding
0.57	GO:0047485	protein N-terminus binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.52	GO:0042802	identical protein binding

0.59	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.51	GO:0032993	protein-DNA complex
0.49	GO:0070013	intracellular organelle lumen
0.49	GO:0012505	endomembrane system
0.46	GO:0031967	organelle envelope
0.45	GO:0005739	mitochondrion
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.81

EC:2.4.2.30

GO:0003950

sp|P09884|DPOLA_HUMAN
DNA polymerase alpha catalytic subunit
Search

POLA1

0.49	DNA polymerase alpha catalytic subunit

0.67	GO:0071897	DNA biosynthetic process
0.65	GO:0006260	DNA replication
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.48	GO:0022616	DNA strand elongation
0.48	GO:0006303	double-strand break repair via nonhomologous end joining
0.41	GO:0070914	UV-damage excision repair
0.41	GO:0008283	cell proliferation
0.39	GO:0016070	RNA metabolic process
0.36	GO:0006289	nucleotide-excision repair
0.36	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle

0.71	GO:0008408	3'-5' exonuclease activity
0.71	GO:0003887	DNA-directed DNA polymerase activity
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.64	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.50	GO:0046982	protein heterodimerization activity
0.40	GO:0003682	chromatin binding
0.38	GO:0019901	protein kinase binding

0.60	GO:0005634	nucleus
0.53	GO:0000428	DNA-directed RNA polymerase complex
0.53	GO:0030894	replisome
0.50	GO:0031974	membrane-enclosed lumen
0.48	GO:0005829	cytosol
0.39	GO:0000785	chromatin
0.38	GO:0012505	endomembrane system
0.37	GO:0031967	organelle envelope
0.35	GO:0016035	zeta DNA polymerase complex

0.71

GO:0003887

sp|P09912|IFI6_HUMAN
Interferon alpha-inducible protein 6
Search

IFI6

0.96	Interferon alpha-inducible protein 6

0.64	GO:0051902	negative regulation of mitochondrial depolarization
0.62	GO:0001836	release of cytochrome c from mitochondria
0.61	GO:1901099	negative regulation of signal transduction in absence of ligand
0.61	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.59	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.59	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0046825	regulation of protein export from nucleus
0.42	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0034097	response to cytokine
0.39	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process

0.45	GO:0005521	lamin binding
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005739	mitochondrion
0.43	GO:0005637	nuclear inner membrane
0.34	GO:0005886	plasma membrane
0.34	GO:0031968	organelle outer membrane
0.33	GO:0015630	microtubule cytoskeleton
0.30	GO:0016021	integral component of membrane

sp|P09913|IFIT2_HUMAN
Interferon-induced protein with tetratricopeptide repeats 2
Search

IFIT2

0.94	Interferon-induced protein with tetratricopeptide repeats 2

0.80	GO:0035457	cellular response to interferon-alpha
0.61	GO:0009615	response to virus
0.55	GO:0032091	negative regulation of protein binding
0.53	GO:0042981	regulation of apoptotic process
0.52	GO:0002252	immune effector process
0.52	GO:0006952	defense response
0.51	GO:0043068	positive regulation of programmed cell death
0.46	GO:0045071	negative regulation of viral genome replication
0.44	GO:0008285	negative regulation of cell proliferation
0.44	GO:0043069	negative regulation of programmed cell death

0.44	GO:0008266	poly(U) RNA binding
0.44	GO:0042802	identical protein binding
0.43	GO:0000339	RNA cap binding
0.41	GO:0003690	double-stranded DNA binding
0.40	GO:0000049	tRNA binding

0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.44	GO:0032587	ruffle membrane
0.43	GO:0045177	apical part of cell
0.43	GO:1902554	serine/threonine protein kinase complex
0.41	GO:0015629	actin cytoskeleton
0.40	GO:0005739	mitochondrion
0.35	GO:0044216	other organism cell
0.35	GO:0018995	host

sp|P09914|IFIT1_HUMAN
Interferon-induced protein with tetratricopeptide repeats 1
Search

0.94	Interferon-induced protein with tetratricopeptide repeats 1

0.75	GO:0009615	response to virus
0.71	GO:0071357	cellular response to type I interferon
0.71	GO:0071360	cellular response to exogenous dsRNA
0.67	GO:0043900	regulation of multi-organism process
0.66	GO:0002831	regulation of response to biotic stimulus
0.65	GO:0002697	regulation of immune effector process
0.63	GO:0002252	immune effector process
0.62	GO:0032101	regulation of response to external stimulus
0.62	GO:0098542	defense response to other organism
0.60	GO:0030581	symbiont intracellular protein transport in host

0.54	GO:0008266	poly(U) RNA binding
0.53	GO:0000339	RNA cap binding
0.48	GO:0003690	double-stranded DNA binding
0.47	GO:0000049	tRNA binding
0.39	GO:0005515	protein binding

0.56	GO:0005829	cytosol
0.54	GO:0032587	ruffle membrane
0.52	GO:0045177	apical part of cell
0.52	GO:1902554	serine/threonine protein kinase complex
0.49	GO:0015629	actin cytoskeleton
0.47	GO:0044217	other organism part
0.47	GO:0018995	host
0.42	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0012505	endomembrane system

sp|P09917|LOX5_HUMAN
Arachidonate 5-lipoxygenase
Search

ALOX5

0.97	Arachidonate 5-lipoxygenase a

0.60	GO:0019370	leukotriene biosynthetic process
0.59	GO:0002540	leukotriene production involved in inflammatory response
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0033559	unsaturated fatty acid metabolic process
0.41	GO:0019372	lipoxygenase pathway
0.39	GO:0001676	long-chain fatty acid metabolic process
0.38	GO:0097746	regulation of blood vessel diameter
0.37	GO:0097176	epoxide metabolic process
0.37	GO:0051240	positive regulation of multicellular organismal process
0.37	GO:0051901	positive regulation of mitochondrial depolarization

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.38	GO:0004464	leukotriene-C4 synthase activity
0.38	GO:0008391	arachidonic acid monooxygenase activity
0.36	GO:0005515	protein binding
0.35	GO:0047977	hepoxilin-epoxide hydrolase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0016853	isomerase activity

0.60	GO:0005641	nuclear envelope lumen
0.58	GO:0016363	nuclear matrix
0.55	GO:0031965	nuclear membrane
0.50	GO:0005829	cytosol
0.50	GO:0005654	nucleoplasm
0.38	GO:0042383	sarcolemma
0.37	GO:0005615	extracellular space
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.35	GO:0030425	dendrite

0.75	EC:1.13.11	GO:0016702
0.38	KEGG:R03059	GO:0004464

sp|P09919|CSF3_HUMAN
Granulocyte colony-stimulating factor
Search

CSF3

0.96	Granulocyte colony-stimulating factor

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.66	GO:0045639	positive regulation of myeloid cell differentiation
0.65	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.64	GO:0042993	positive regulation of transcription factor import into nucleus
0.63	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.63	GO:0051897	positive regulation of protein kinase B signaling
0.63	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.63	GO:0032092	positive regulation of protein binding
0.63	GO:0030223	neutrophil differentiation

0.81	GO:0005125	cytokine activity
0.73	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.57	GO:0008083	growth factor activity
0.54	GO:0019899	enzyme binding

0.66

GO:0005576

extracellular region

sp|P09923|PPBI_HUMAN
Intestinal-type alkaline phosphatase
Search

0.47	Intestinal-type alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.41	GO:0071310	cellular response to organic substance
0.41	GO:0001958	endochondral ossification
0.40	GO:0071772	response to BMP
0.40	GO:0033280	response to vitamin D
0.38	GO:0003006	developmental process involved in reproduction
0.38	GO:0071495	cellular response to endogenous stimulus
0.38	GO:0046677	response to antibiotic
0.38	GO:0006501	C-terminal protein lipidation
0.37	GO:0009612	response to mechanical stimulus

0.79	GO:0004035	alkaline phosphatase activity
0.46	GO:0002020	protease binding
0.39	GO:0000287	magnesium ion binding
0.38	GO:0008270	zinc ion binding
0.35	GO:0016462	pyrophosphatase activity
0.34	GO:0042803	protein homodimerization activity

0.43	GO:0031225	anchored component of membrane
0.42	GO:0005886	plasma membrane
0.42	GO:0009986	cell surface
0.42	GO:0065010	extracellular membrane-bounded organelle
0.38	GO:0098552	side of membrane
0.38	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0030016	myofibril
0.35	GO:0005903	brush border
0.30	GO:0016021	integral component of membrane

0.79

GO:0004035

sp|P09936|UCHL1_HUMAN
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Search

UCHL1

0.56	Ubiquitin carboxyl-terminal hydrolase

0.74	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.54	GO:0007412	axon target recognition
0.54	GO:0019896	axonal transport of mitochondrion
0.53	GO:0042755	eating behavior
0.53	GO:0002931	response to ischemia
0.53	GO:0007628	adult walking behavior
0.52	GO:0048747	muscle fiber development
0.52	GO:0043407	negative regulation of MAP kinase activity
0.51	GO:0050905	neuromuscular process

0.79	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.61	GO:0016874	ligase activity
0.56	GO:0031694	alpha-2A adrenergic receptor binding
0.51	GO:0043130	ubiquitin binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0008242	omega peptidase activity
0.48	GO:0004197	cysteine-type endopeptidase activity

0.52	GO:1904115	axon cytoplasm
0.51	GO:0044306	neuron projection terminus
0.51	GO:0043209	myelin sheath
0.50	GO:0043025	neuronal cell body
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.40	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0043196	varicosity

0.61

GO:0016874

sp|P09958|FURIN_HUMAN
Furin
Search

FURIN

0.95	Truncated furin endoprotease

0.62	GO:0090472	dibasic protein processing
0.61	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.61	GO:0032902	nerve growth factor production
0.61	GO:0032911	negative regulation of transforming growth factor beta1 production
0.59	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process
0.57	GO:0016486	peptide hormone processing
0.57	GO:0031638	zymogen activation
0.54	GO:0008283	cell proliferation
0.54	GO:0006465	signal peptide processing
0.52	GO:0010951	negative regulation of endopeptidase activity

0.69	GO:0004252	serine-type endopeptidase activity
0.60	GO:0048406	nerve growth factor binding
0.56	GO:0002020	protease binding
0.54	GO:0042277	peptide binding
0.54	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0046872	metal ion binding

0.55	GO:0030140	trans-Golgi network transport vesicle
0.54	GO:0098857	membrane microdomain
0.54	GO:0005802	trans-Golgi network
0.52	GO:0009986	cell surface
0.51	GO:0000139	Golgi membrane
0.50	GO:0005783	endoplasmic reticulum
0.40	GO:0010008	endosome membrane
0.37	GO:0005576	extracellular region
0.36	GO:0005796	Golgi lumen
0.35	GO:0005886	plasma membrane

0.69

GO:0004252

sp|P09960|LKHA4_HUMAN
Leukotriene A-4 hydrolase
Search

LTA4H

0.79	Leukotriene A-4 hydrolase

0.85	GO:0019370	leukotriene biosynthetic process
0.60	GO:0006508	proteolysis
0.56	GO:0043171	peptide catabolic process
0.45	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.44	GO:0030593	neutrophil chemotaxis
0.43	GO:0044267	cellular protein metabolic process
0.42	GO:0006954	inflammatory response
0.42	GO:0044255	cellular lipid metabolic process
0.36	GO:0060509	Type I pneumocyte differentiation
0.35	GO:0043312	neutrophil degranulation

0.80	GO:0004463	leukotriene-A4 hydrolase activity
0.66	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.61	GO:0004301	epoxide hydrolase activity
0.53	GO:0004177	aminopeptidase activity
0.47	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.32	GO:0016841	ammonia-lyase activity

0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen

0.80	EC:3.3.2.6	GO:0004463
0.80	KEGG:R03057	GO:0004463

sp|P09972|ALDOC_HUMAN
Fructose-bisphosphate aldolase C
Search

ALDOC

0.55	Fructose-bisphosphate aldolase C

0.70	GO:0006096	glycolytic process
0.57	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.52	GO:0030855	epithelial cell differentiation
0.42	GO:0006000	fructose metabolic process
0.42	GO:0046716	muscle cell cellular homeostasis
0.42	GO:0007339	binding of sperm to zona pellucida
0.41	GO:0006941	striated muscle contraction
0.38	GO:0051289	protein homotetramerization
0.38	GO:0006754	ATP biosynthetic process
0.38	GO:0008360	regulation of cell shape

0.78	GO:0004332	fructose-bisphosphate aldolase activity
0.51	GO:0008092	cytoskeletal protein binding
0.44	GO:0070061	fructose binding
0.41	GO:0045296	cadherin binding
0.36	GO:0002020	protease binding
0.36	GO:0042802	identical protein binding
0.35	GO:0061609	fructose-1-phosphate aldolase activity
0.34	GO:0051117	ATPase binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0003723	RNA binding

0.44	GO:0005739	mitochondrion
0.43	GO:0061827	sperm head
0.42	GO:0070062	extracellular exosome
0.39	GO:0005856	cytoskeleton
0.39	GO:0005829	cytosol
0.38	GO:0035686	sperm fibrous sheath
0.38	GO:0031430	M band
0.37	GO:0031674	I band
0.36	GO:0043209	myelin sheath
0.35	GO:1904724	tertiary granule lumen

0.78

EC:4.1.2.13

GO:0004332

sp|P0C024|NUDT7_HUMAN
Peroxisomal coenzyme A diphosphatase NUDT7
Search

NUDT7

0.94	Peroxisomal coenzyme A diphosphatase NUDT7

0.65	GO:0009132	nucleoside diphosphate metabolic process
0.52	GO:0015938	coenzyme A catabolic process
0.49	GO:0046356	acetyl-CoA catabolic process
0.49	GO:0050873	brown fat cell differentiation
0.39	GO:0009062	fatty acid catabolic process

0.67	GO:0030145	manganese ion binding
0.60	GO:0000287	magnesium ion binding
0.55	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0.49	GO:0003986	acetyl-CoA hydrolase activity
0.47	GO:0030515	snoRNA binding
0.45	GO:0005102	receptor binding

0.45	GO:0005777	peroxisome
0.41	GO:0031907	microbody lumen
0.30	GO:0016020	membrane

0.55	EC:3.6.1	GO:0016818
0.49	KEGG:R00227	GO:0003986

sp|P0C025|NUD17_HUMAN
Nucleoside diphosphate-linked moiety X motif 17
Search

NUDT17

0.97	LOW QUALITY PROTEIN: nucleoside diphosphate-linked moiety X motif 17

0.33	GO:0097659	nucleic acid-templated transcription
0.32	GO:0010467	gene expression
0.32	GO:0034645	cellular macromolecule biosynthetic process
0.32	GO:0008299	isoprenoid biosynthetic process

0.51	GO:0016787	hydrolase activity
0.37	GO:0046872	metal ion binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0003677	DNA binding
0.32	GO:0004452	isopentenyl-diphosphate delta-isomerase activity

0.51	EC:3	GO:0016787
0.32	KEGG:R01123	GO:0004452

sp|P0C091|FREM3_HUMAN
FRAS1-related extracellular matrix protein 3
Search

FREM2

0.92	FRAS1-related extracellular matrix protein 3

0.60	GO:0007154	cell communication
0.58	GO:0048839	inner ear development
0.57	GO:0007507	heart development
0.56	GO:0002009	morphogenesis of an epithelium
0.44	GO:0033334	fin morphogenesis
0.39	GO:0007155	cell adhesion

0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.73	GO:0005604	basement membrane
0.42	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P0C0E4|RB40L_HUMAN
Ras-related protein Rab-40A-like
Search

RAB40B

0.96	SOCS box-containing protein RAR2A

0.68	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.48	GO:0072659	protein localization to plasma membrane
0.48	GO:0017157	regulation of exocytosis
0.47	GO:0006904	vesicle docking involved in exocytosis
0.46	GO:1990967	multi-organism toxin transport
0.44	GO:0009306	protein secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0030667	secretory granule membrane
0.48	GO:0008021	synaptic vesicle
0.45	GO:0005768	endosome
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005635	nuclear envelope
0.39	GO:0005886	plasma membrane
0.36	GO:0005739	mitochondrion

sp|P0C0L4|CO4A_HUMAN
Complement C4-A
Search

0.95	Complement component 4

0.77	GO:0006956	complement activation
0.74	GO:0010951	negative regulation of endopeptidase activity
0.73	GO:0006954	inflammatory response
0.58	GO:0016064	immunoglobulin mediated immune response
0.43	GO:2000427	positive regulation of apoptotic cell clearance
0.42	GO:0045087	innate immune response
0.40	GO:0030449	regulation of complement activation
0.40	GO:0032490	detection of molecule of bacterial origin
0.38	GO:0008228	opsonization
0.37	GO:0043687	post-translational protein modification

0.74	GO:0004866	endopeptidase inhibitor activity
0.44	GO:0001848	complement binding
0.42	GO:0001846	opsonin binding
0.38	GO:0030246	carbohydrate binding
0.37	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding

0.71	GO:0005615	extracellular space
0.44	GO:0030425	dendrite
0.44	GO:0030424	axon
0.43	GO:0045202	synapse
0.41	GO:0030054	cell junction
0.41	GO:1903561	extracellular vesicle
0.40	GO:0043025	neuronal cell body
0.37	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0044217	other organism part
0.35	GO:0005886	plasma membrane

0.37

GO:0004252

sp|P0C0L5|CO4B_HUMAN
Complement C4-B
Search

0.95	Complement component 4

0.77	GO:0006956	complement activation
0.74	GO:0010951	negative regulation of endopeptidase activity
0.73	GO:0006954	inflammatory response
0.58	GO:0016064	immunoglobulin mediated immune response
0.43	GO:2000427	positive regulation of apoptotic cell clearance
0.42	GO:0045087	innate immune response
0.40	GO:0030449	regulation of complement activation
0.40	GO:0032490	detection of molecule of bacterial origin
0.38	GO:0008228	opsonization
0.37	GO:0043687	post-translational protein modification

0.74	GO:0004866	endopeptidase inhibitor activity
0.44	GO:0001848	complement binding
0.42	GO:0001846	opsonin binding
0.38	GO:0030246	carbohydrate binding
0.37	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding

0.71	GO:0005615	extracellular space
0.44	GO:0030425	dendrite
0.44	GO:0030424	axon
0.43	GO:0045202	synapse
0.41	GO:0030054	cell junction
0.41	GO:1903561	extracellular vesicle
0.40	GO:0043025	neuronal cell body
0.37	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0044216	other organism cell
0.35	GO:0005886	plasma membrane

0.37

GO:0004252

sp|P0C0P6|NPS_HUMAN
Neuropeptide S
Search

NPS

0.97	Neuropeptide S

0.80	GO:0007218	neuropeptide signaling pathway
0.68	GO:0045760	positive regulation of action potential
0.67	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.67	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.65	GO:0008542	visual learning
0.47	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P0C0S5|H2AZ_HUMAN
Histone H2A.Z
Search

sp|P0C0S8|H2A1_HUMAN
Histone H2A type 1
Search

0.10	Histone H2A type 1-D

0.54	GO:0006342	chromatin silencing
0.35	GO:0006334	nucleosome assembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.36	GO:0019899	enzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.38	GO:0070062	extracellular exosome

sp|P0C1H6|H2BFM_HUMAN
Histone H2B type F-M
Search

H2BFWT

0.97	H2B histone family member W testis-specific

0.46

GO:0006334

nucleosome assembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.36	GO:0012505	endomembrane system
0.36	GO:0000791	euchromatin
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C1S8|WEE2_HUMAN
Wee1-like protein kinase 2
Search

WEE2

0.88	Wee1-like protein kinase 2-A

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0000278	mitotic cell cycle
0.59	GO:1900194	negative regulation of oocyte maturation
0.59	GO:0035038	female pronucleus assembly
0.57	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.56	GO:0007143	female meiotic nuclear division
0.56	GO:0060631	regulation of meiosis I
0.46	GO:0030010	establishment of cell polarity
0.45	GO:0048812	neuron projection morphogenesis
0.44	GO:0000226	microtubule cytoskeleton organization

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.63	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0003697	single-stranded DNA binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.48	GO:0005829	cytosol
0.45	GO:0044446	intracellular organelle part
0.39	GO:0043232	intracellular non-membrane-bounded organelle

0.79

GO:0004715

sp|P0C1Z6|TFPT_HUMAN
TCF3 fusion partner
Search

TFPT

0.97	LOW QUALITY PROTEIN: TCF3 fusion partner

0.77	GO:0006915	apoptotic process
0.47	GO:0007165	signal transduction
0.38	GO:0006310	DNA recombination
0.38	GO:0006281	DNA repair
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0008584	male gonad development
0.36	GO:0006355	regulation of transcription, DNA-templated
0.36	GO:0016579	protein deubiquitination
0.36	GO:0043065	positive regulation of apoptotic process

0.41	GO:0019901	protein kinase binding
0.37	GO:0003677	DNA binding
0.35	GO:0046982	protein heterodimerization activity

0.58	GO:0031965	nuclear membrane
0.58	GO:0031011	Ino80 complex
0.53	GO:0005654	nucleoplasm
0.42	GO:0005884	actin filament
0.35	GO:0005737	cytoplasm

sp|P0C221|CC175_HUMAN
Coiled-coil domain-containing protein 175
Search

CCDC175

0.97	Coiled-coil domain-containing protein 175

0.65	GO:0035023	regulation of Rho protein signal transduction
0.56	GO:0065009	regulation of molecular function
0.37	GO:0007018	microtubule-based movement

0.65	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C263|SBK2_HUMAN
Serine/threonine-protein kinase SBK2
Search

SBK2

0.91	LOW QUALITY PROTEIN: serine/threonine-protein kinase SBK2

0.63	GO:0006468	protein phosphorylation
0.48	GO:0007266	Rho protein signal transduction
0.48	GO:0031098	stress-activated protein kinase signaling cascade
0.47	GO:0032147	activation of protein kinase activity
0.46	GO:0043408	regulation of MAPK cascade
0.46	GO:0016477	cell migration
0.45	GO:0007346	regulation of mitotic cell cycle
0.45	GO:0042981	regulation of apoptotic process
0.45	GO:0030036	actin cytoskeleton organization
0.38	GO:0018210	peptidyl-threonine modification

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0048365	Rac GTPase binding
0.33	GO:0050265	RNA uridylyltransferase activity
0.32	GO:0016787	hydrolase activity

0.41	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.32	GO:0032153	cell division site
0.31	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|P0C264|SBK3_HUMAN
Uncharacterized serine/threonine-protein kinase SBK3
Search

SBK3

0.79	Serine/threonine-protein kinase SBK1

0.63	GO:0006468	protein phosphorylation
0.37	GO:0018210	peptidyl-threonine modification
0.37	GO:0018209	peptidyl-serine modification
0.34	GO:0005978	glycogen biosynthetic process
0.33	GO:0006898	receptor-mediated endocytosis
0.33	GO:0018212	peptidyl-tyrosine modification
0.33	GO:1902531	regulation of intracellular signal transduction
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0046898	response to cycloheximide
0.33	GO:0032147	activation of protein kinase activity

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005516	calmodulin binding
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0004871	signal transducer activity
0.33	GO:0004713	protein tyrosine kinase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0005509	calcium ion binding

0.35	GO:0005964	phosphorylase kinase complex
0.33	GO:0005871	kinesin complex
0.32	GO:0005634	nucleus
0.32	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.66

GO:0004674

sp|P0C2L3|F163B_HUMAN
Protein FAM163B
Search

0.30

GO:0044425

membrane part

sp|P0C2S0|CTXN2_HUMAN
Cortexin-2
Search

CTXN2

0.97	Cortexin 2

0.33

GO:0007417

central nervous system development

0.30

GO:0044425

membrane part

sp|P0C2W1|FBSP1_HUMAN
F-box/SPRY domain-containing protein 1
Search

FBXO45

0.71	F-box/SPRY domain-containing protein 1

0.75	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.73	GO:0016567	protein ubiquitination
0.72	GO:0007274	neuromuscular synaptic transmission
0.70	GO:0007399	nervous system development
0.67	GO:0045732	positive regulation of protein catabolic process
0.58	GO:0010629	negative regulation of gene expression
0.57	GO:0050808	synapse organization
0.57	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.56	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.56	GO:0060322	head development

0.45	GO:0005515	protein binding
0.40	GO:0004842	ubiquitin-protein transferase activity

0.74	GO:0019005	SCF ubiquitin ligase complex
0.72	GO:0045495	pole plasm
0.71	GO:0045202	synapse
0.69	GO:0030054	cell junction
0.64	GO:0005938	cell cortex
0.56	GO:0097458	neuron part
0.53	GO:0005634	nucleus
0.51	GO:0098590	plasma membrane region
0.41	GO:0044297	cell body
0.40	GO:0120025	plasma membrane bounded cell projection

0.40

KEGG:R03876

GO:0004842

sp|P0C2W7|CT47B_HUMAN
Cancer/testis antigen 47B
Search

CT47B1

0.97	Cancer/testis antigen 47B

0.48	GO:0030261	chromosome condensation
0.45	GO:0009254	peptidoglycan turnover
0.40	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.39	GO:0090501	RNA phosphodiester bond hydrolysis
0.39	GO:0022900	electron transport chain
0.39	GO:0010467	gene expression
0.39	GO:0043043	peptide biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0009059	macromolecule biosynthetic process
0.36	GO:0016311	dephosphorylation

0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0003676	nucleic acid binding
0.40	GO:0032550	purine ribonucleoside binding
0.40	GO:0019001	guanyl nucleotide binding
0.40	GO:0003735	structural constituent of ribosome
0.40	GO:0009055	electron transfer activity
0.40	GO:0004540	ribonuclease activity
0.39	GO:0020037	heme binding
0.38	GO:0003924	GTPase activity
0.38	GO:0046872	metal ion binding

0.43	GO:0019867	outer membrane
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0044444	cytoplasmic part
0.38	GO:0031226	intrinsic component of plasma membrane
0.37	GO:0000178	exosome (RNase complex)
0.36	GO:0044462	external encapsulating structure part
0.36	GO:0032993	protein-DNA complex
0.36	GO:0030313	cell envelope
0.36	GO:0044446	intracellular organelle part

0.42

GO:0004553

sp|P0C2Y1|NBPF7_HUMAN
Putative neuroblastoma breakpoint family member 7
Search

0.87	Neuroblastoma breakpoint family member 9

0.56

GO:1903955

positive regulation of protein targeting to mitochondrion

0.40

GO:0003723

RNA binding

0.48

GO:0005737

cytoplasm

sp|P0C5J1|F86B2_HUMAN
Putative protein N-methyltransferase FAM86B2
Search

EEF2KMT

0.89	Protein-lysine N-methyltransferase EEF2KMT

0.63	GO:0032259	methylation
0.53	GO:0018205	peptidyl-lysine modification
0.53	GO:0008213	protein alkylation

0.63	GO:0008168	methyltransferase activity
0.45	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0005515	protein binding

0.43	GO:0043234	protein complex
0.43	GO:0005829	cytosol

0.63

GO:0008168

sp|P0C5K6|CT18_HUMAN
Putative tumor antigen NA88-A
Search

0.96	Cancer/testis antigen 18 (Fragment)

sp|P0C5K7|CT62_HUMAN
Cancer/testis antigen 62
Search

CT62

0.97	Cancer/testis antigen 62

sp|P0C5Y4|KRA14_HUMAN
Keratin-associated protein 1-4
Search

KAP1.3

0.97	Keratin intermediate-filament type I protein variant 2

0.39

GO:0031424

keratinization

0.36	GO:0030280	structural constituent of epidermis
0.35	GO:0042802	identical protein binding
0.34	GO:0039660	structural constituent of virion

0.83	GO:0045095	keratin filament
0.36	GO:0005829	cytosol

sp|P0C5Y9|H2AB1_HUMAN
Histone H2A-Bbd type 1
Search

0.49	Histone-fold-containing protein

0.49	GO:0006342	chromatin silencing
0.43	GO:0006334	nucleosome assembly
0.39	GO:0006397	mRNA processing
0.34	GO:0016569	covalent chromatin modification

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.34	GO:0003682	chromatin binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.45	GO:0035327	transcriptionally active chromatin
0.44	GO:0031974	membrane-enclosed lumen
0.34	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P0C5Z0|H2AB2_HUMAN
Histone H2A-Bbd type 2/3
Search

0.49	Histone-fold-containing protein

0.50	GO:0006342	chromatin silencing
0.43	GO:0006334	nucleosome assembly
0.39	GO:0006397	mRNA processing
0.34	GO:0016569	covalent chromatin modification

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.34	GO:0003682	chromatin binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.45	GO:0035327	transcriptionally active chromatin
0.45	GO:0031974	membrane-enclosed lumen
0.34	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P0C604|OR4A8_HUMAN
Olfactory receptor 4A8
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0055114	oxidation-reduction process

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.32	GO:0016491	oxidoreductase activity

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

sp|P0C617|O5AL1_HUMAN
Olfactory receptor 5AL1
Search

0.44	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.51	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C623|OR4Q2_HUMAN
Olfactory receptor 4Q2
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C626|OR5G3_HUMAN
Olfactory receptor 5G3
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.56	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C628|O5AC1_HUMAN
Olfactory receptor 5AC1
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.56	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C629|O10J4_HUMAN
Olfactory receptor 10J4
Search

0.39	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0007210	serotonin receptor signaling pathway
0.34	GO:0007338	single fertilization

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.41	GO:0099589	serotonin receptor activity
0.39	GO:0030594	neurotransmitter receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C645|OR4E1_HUMAN
Olfactory receptor 4E1
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.37	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C646|O52Z1_HUMAN
Olfactory receptor 52Z1
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0050890	cognition
0.34	GO:0015893	drug transport
0.34	GO:0015669	gas transport
0.33	GO:0072337	modified amino acid transport
0.33	GO:0006835	dicarboxylic acid transport
0.33	GO:0051180	vitamin transport
0.33	GO:0051181	cofactor transport
0.33	GO:0006470	protein dephosphorylation

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005344	oxygen carrier activity
0.34	GO:0019825	oxygen binding
0.34	GO:0008517	folic acid transmembrane transporter activity
0.34	GO:0005542	folic acid binding
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.56	GO:0005886	plasma membrane
0.34	GO:0005833	hemoglobin complex
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.3.16

GO:0004721

sp|P0C671|CF222_HUMAN
Uncharacterized protein C6orf222
Search

sp|P0C672|TSN19_HUMAN
Putative tetraspanin-19
Search

TSPAN19

0.55	Tetraspanin

0.49

GO:0007166

cell surface receptor signaling pathway

0.47

GO:0005887

integral component of plasma membrane

sp|P0C6A0|ZGLP1_HUMAN
GATA-type zinc finger protein 1
Search

ZGLP1

0.97	GATA-type zinc finger protein 1

0.58	GO:0048599	oocyte development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0007283	spermatogenesis
0.51	GO:0051253	negative regulation of RNA metabolic process
0.51	GO:0010558	negative regulation of macromolecule biosynthetic process
0.51	GO:0031327	negative regulation of cellular biosynthetic process
0.48	GO:0006366	transcription by RNA polymerase II
0.47	GO:0051254	positive regulation of RNA metabolic process

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001085	RNA polymerase II transcription factor binding
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003682	chromatin binding
0.46	GO:0003690	double-stranded DNA binding
0.31	GO:0016740	transferase activity

0.48	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.31

GO:0016740

sp|P0C6C1|AN34C_HUMAN
Ankyrin repeat domain-containing protein 34C
Search

ANKRD34C

0.95	Ankyrin repeat domain-containing protein 34C

0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|P0C6P0|BCL8_HUMAN
Putative protein BCL8
Search

0.55	LPS-responsive vesicle trafficking, beach and anchor containing (Fragment)

0.60	GO:0007416	synapse assembly
0.59	GO:0016358	dendrite development
0.56	GO:0008104	protein localization
0.41	GO:0006892	post-Golgi vesicle-mediated transport
0.38	GO:0046907	intracellular transport
0.38	GO:0070727	cellular macromolecule localization
0.38	GO:0015833	peptide transport

0.66	GO:0019901	protein kinase binding
0.42	GO:0051018	protein kinase A binding

0.67	GO:0005802	trans-Golgi network
0.59	GO:0005829	cytosol
0.49	GO:0005886	plasma membrane
0.40	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.30	GO:0044425	membrane part

sp|P0C6S8|LIGO3_HUMAN
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3
Search

0.96	Leucine rich repeat and Ig domain containing 3

0.52	GO:0061564	axon development
0.51	GO:0048667	cell morphogenesis involved in neuron differentiation
0.51	GO:0048812	neuron projection morphogenesis
0.48	GO:0051965	positive regulation of synapse assembly
0.40	GO:0031102	neuron projection regeneration
0.40	GO:0048678	response to axon injury
0.38	GO:0021628	olfactory nerve formation
0.38	GO:0071699	olfactory placode morphogenesis
0.35	GO:0042552	myelination
0.33	GO:0007165	signal transduction

0.36

GO:0005154

epidermal growth factor receptor binding

0.49	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P0C6T2|OST4_HUMAN
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
Search

OST4

0.97	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit

0.54	GO:0006487	protein N-linked glycosylation
0.52	GO:0018196	peptidyl-asparagine modification
0.35	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.45	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.35	GO:0070003	threonine-type peptidase activity
0.34	GO:0004175	endopeptidase activity

0.55	GO:0008250	oligosaccharyltransferase complex
0.35	GO:0019774	proteasome core complex, beta-subunit complex
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:2.4.1.119

GO:0004579

sp|P0C7A2|F153B_HUMAN
Protein FAM153B
Search

sp|P0C7H8|KRA23_HUMAN
Keratin-associated protein 2-3
Search

0.96	Keratin-associated protein 2-3

0.44	GO:0031424	keratinization
0.32	GO:0006508	proteolysis
0.32	GO:0009405	pathogenesis

0.36	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0090729	toxin activity
0.32	GO:0046872	metal ion binding

0.82	GO:0045095	keratin filament
0.39	GO:0005829	cytosol

0.33

GO:0004222

sp|P0C7H9|U17L7_HUMAN
Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7
Search

0.92	Ubiquitin carboxyl-terminal hydrolase DUB-1

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.41	GO:0006915	apoptotic process
0.39	GO:1900245	positive regulation of MDA-5 signaling pathway
0.38	GO:0090315	negative regulation of protein targeting to membrane
0.38	GO:0031064	negative regulation of histone deacetylation
0.38	GO:1900246	positive regulation of RIG-I signaling pathway
0.38	GO:0042981	regulation of apoptotic process
0.38	GO:1900027	regulation of ruffle assembly
0.38	GO:0034260	negative regulation of GTPase activity

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.37	GO:0005540	hyaluronic acid binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005829	cytosol
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.77

EC:3.4.19.12

GO:0036459

sp|P0C7I0|U17L8_HUMAN
Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8
Search

0.91	Ubiquitin carboxyl-terminal hydrolase 17

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0006915	apoptotic process
0.38	GO:1904035	regulation of epithelial cell apoptotic process
0.37	GO:1900245	positive regulation of MDA-5 signaling pathway
0.36	GO:0007283	spermatogenesis
0.36	GO:0090315	negative regulation of protein targeting to membrane
0.36	GO:0031064	negative regulation of histone deacetylation
0.36	GO:1900246	positive regulation of RIG-I signaling pathway
0.36	GO:1900027	regulation of ruffle assembly

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.37	GO:0005540	hyaluronic acid binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005829	cytosol
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.77

EC:3.4.19.12

GO:0036459

sp|P0C7I6|CC159_HUMAN
Coiled-coil domain-containing protein 159
Search

CCDC159

0.97	Coiled-coil domain-containing protein 159

sp|P0C7L1|ISK8_HUMAN
Serine protease inhibitor Kazal-type 8
Search

SPINK8

0.97	Serine protease inhibitor Kazal-type 8

0.66	GO:1900004	negative regulation of serine-type endopeptidase activity
0.64	GO:0060046	regulation of acrosome reaction
0.55	GO:0006508	proteolysis

0.58	GO:0004867	serine-type endopeptidase inhibitor activity
0.56	GO:0008233	peptidase activity

0.61	GO:0001669	acrosomal vesicle
0.55	GO:0005615	extracellular space

0.56

GO:0008233

sp|P0C7M3|SFTA3_HUMAN
Surfactant-associated protein 3
Search

sp|P0C7M4|RHF2B_HUMAN
Rhox homeobox family member 2B
Search

0.97	Rhox homeobox family member 2

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.51	GO:0007275	multicellular organism development
0.45	GO:0006351	transcription, DNA-templated
0.42	GO:0051253	negative regulation of RNA metabolic process
0.42	GO:0010558	negative regulation of macromolecule biosynthetic process
0.42	GO:0031327	negative regulation of cellular biosynthetic process
0.42	GO:0060429	epithelium development
0.40	GO:0009653	anatomical structure morphogenesis

0.63	GO:0043565	sequence-specific DNA binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P0C7M6|IQCF3_HUMAN
IQ domain-containing protein F3
Search

0.96	IQ domain-containing protein F3

0.58	GO:2000344	positive regulation of acrosome reaction
0.58	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.37	GO:0007107	membrane addition at site of cytokinesis
0.37	GO:0030050	vesicle transport along actin filament
0.37	GO:0048313	Golgi inheritance
0.37	GO:0045033	peroxisome inheritance
0.36	GO:0007118	budding cell apical bud growth
0.36	GO:0000011	vacuole inheritance
0.36	GO:0000132	establishment of mitotic spindle orientation
0.36	GO:0009826	unidimensional cell growth

0.75	GO:0005516	calmodulin binding
0.37	GO:0000146	microfilament motor activity
0.36	GO:0003735	structural constituent of ribosome
0.35	GO:0051015	actin filament binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.34	GO:0003676	nucleic acid binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0001669	acrosomal vesicle
0.37	GO:0071563	Myo2p-Vac17p-Vac8p transport complex
0.36	GO:0031941	filamentous actin
0.36	GO:0000131	incipient cellular bud site
0.36	GO:0032432	actin filament bundle
0.36	GO:0005934	cellular bud tip
0.36	GO:0043332	mating projection tip
0.36	GO:0005935	cellular bud neck
0.36	GO:0005840	ribosome
0.36	GO:0000329	fungal-type vacuole membrane

sp|P0C7M7|ACSM4_HUMAN
Acyl-coenzyme A synthetase ACSM4, mitochondrial
Search

ACSM4

0.88	Acyl-coenzyme A synthetase ACSM4, mitochondrial

0.48	GO:0035383	thioester metabolic process
0.48	GO:0006633	fatty acid biosynthetic process
0.44	GO:0006732	coenzyme metabolic process
0.41	GO:0003008	system process
0.40	GO:0006793	phosphorus metabolic process
0.39	GO:0042632	cholesterol homeostasis

0.60	GO:0047760	butyrate-CoA ligase activity
0.58	GO:0003996	acyl-CoA ligase activity
0.55	GO:0004321	fatty-acyl-CoA synthase activity
0.52	GO:0015645	fatty acid ligase activity
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0032553	ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0046872	metal ion binding
0.39	GO:0005549	odorant binding

0.50

GO:0005759

mitochondrial matrix

0.60

EC:6.2.1.2

GO:0047760

sp|P0C7M8|CLC2L_HUMAN
C-type lectin domain family 2 member L
Search

CLEC2L

0.97	C-type lectin domain family 2 member L

0.69

GO:0030246

carbohydrate binding

0.30

GO:0044425

membrane part

sp|P0C7N1|OR8U8_HUMAN
Olfactory receptor 8U8
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C7N4|T191B_HUMAN
Transmembrane protein 191B
Search

TMEM191C

0.95	Transmembrane protein 191C

0.30

GO:0044425

membrane part

sp|P0C7N5|OR8U9_HUMAN
Olfactory receptor 8U9
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C7N8|OR9G9_HUMAN
Olfactory receptor 9G9
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.47	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C7P0|CISD3_HUMAN
CDGSH iron-sulfur domain-containing protein 3, mitochondrial
Search

CISD3

0.70	Iron-binding zinc finger CDGSH type

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.35	GO:0046872	metal ion binding

0.56	GO:0043231	intracellular membrane-bounded organelle
0.47	GO:0044444	cytoplasmic part

sp|P0C7P1|RBY1D_HUMAN
RNA-binding motif protein, Y chromosome, family 1 member D
Search

0.60	RNA binding motif protein, X-linked

0.49	GO:0006509	membrane protein ectodomain proteolysis
0.49	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.49	GO:0071347	cellular response to interleukin-1
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0008380	RNA splicing
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0051259	protein oligomerization
0.44	GO:0006397	mRNA processing
0.43	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.43	GO:0048026	positive regulation of mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.48	GO:0001047	core promoter binding
0.46	GO:0003682	chromatin binding
0.43	GO:0042802	identical protein binding
0.43	GO:0019904	protein domain specific binding

0.51	GO:0044530	supraspliceosomal complex
0.49	GO:0005719	nuclear euchromatin
0.47	GO:0071013	catalytic step 2 spliceosome
0.47	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P0C7P2|RFL3S_HUMAN
Putative protein RFPL3S
Search

sp|P0C7P3|SLN14_HUMAN
Protein SLFN14
Search

0.96	Schlafen family member 10 homologue, CAST/EiJ strain specific

0.62	GO:0036345	platelet maturation
0.53	GO:0016075	rRNA catabolic process
0.52	GO:0006402	mRNA catabolic process
0.49	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.48	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.45	GO:0051607	defense response to virus
0.42	GO:0071287	cellular response to manganese ion
0.42	GO:0071286	cellular response to magnesium ion
0.35	GO:0016032	viral process
0.35	GO:0043043	peptide biosynthetic process

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0043022	ribosome binding
0.50	GO:0004521	endoribonuclease activity
0.43	GO:0000049	tRNA binding
0.35	GO:0003735	structural constituent of ribosome

0.51	GO:0005634	nucleus
0.40	GO:0016235	aggresome
0.40	GO:0005737	cytoplasm
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|P0C7P4|UCRIL_HUMAN
Putative cytochrome b-c1 complex subunit Rieske-like protein 1
Search

UQCRFS1

0.69	Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

0.61	GO:0022900	electron transport chain
0.37	GO:0009725	response to hormone
0.37	GO:0046677	response to antibiotic
0.36	GO:0042493	response to drug
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.74	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.38	GO:0046872	metal ion binding
0.37	GO:0032403	protein complex binding

0.61	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.47	GO:0098798	mitochondrial protein complex
0.46	GO:0070069	cytochrome complex
0.45	GO:1990204	oxidoreductase complex
0.42	GO:0098796	membrane protein complex
0.40	GO:0043209	myelin sheath
0.30	GO:0016021	integral component of membrane

0.74

GO:0016681

sp|P0C7Q2|ARMS2_HUMAN
Age-related maculopathy susceptibility protein 2
Search

ARMS2

0.96	Age-related maculopathy susceptibility protein 2

0.85

GO:0001895

retina homeostasis

0.85	GO:0001917	photoreceptor inner segment
0.61	GO:0005739	mitochondrion

sp|P0C7Q3|FA58B_HUMAN
Putative cyclin-related protein FAM58B
Search

0.93

Cyclin-Q

0.76	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.73	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.66	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0032147	activation of protein kinase activity
0.56	GO:0043410	positive regulation of MAPK cascade
0.42	GO:0016310	phosphorylation

0.71	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.58	GO:0030295	protein kinase activator activity
0.43	GO:0016301	kinase activity
0.40	GO:0005515	protein binding

0.73	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.57	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.71

GO:0016538

sp|P0C7Q5|S35G4_HUMAN
Putative solute carrier family 35 member G4
Search

0.63	Acyl-malonyl condensing enzyme 1

0.30

GO:0044425

membrane part

sp|P0C7Q6|S35G6_HUMAN
Solute carrier family 35 member G6
Search

0.63	Acyl-malonyl condensing enzyme 1

0.30

GO:0044425

membrane part

sp|P0C7T2|OR2T7_HUMAN
Olfactory receptor 2T7
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0007017	microtubule-based process
0.33	GO:0007010	cytoskeleton organization

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005886	plasma membrane
0.33	GO:0005874	microtubule
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P0C7T3|O56A5_HUMAN
Olfactory receptor 56A5
Search

0.97	Olfactory receptor family 56 subfamily A member 5

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.53	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.52	GO:0001963	synaptic transmission, dopaminergic
0.52	GO:0048148	behavioral response to cocaine
0.52	GO:0014059	regulation of dopamine secretion
0.52	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.52	GO:0007194	negative regulation of adenylate cyclase activity
0.52	GO:0048149	behavioral response to ethanol

0.76	GO:0004984	olfactory receptor activity
0.66	GO:0004930	G-protein coupled receptor activity
0.52	GO:0035240	dopamine binding
0.47	GO:0030594	neurotransmitter receptor activity

0.52	GO:0005886	plasma membrane
0.51	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|P0C7T5|ATX1L_HUMAN
Ataxin-1-like
Search

ATXN1L

0.80	Brother of ataxin-1

0.66	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.63	GO:0048286	lung alveolus development
0.63	GO:0035176	social behavior
0.61	GO:0007613	memory
0.61	GO:0007612	learning
0.59	GO:0030198	extracellular matrix organization
0.58	GO:0007420	brain development
0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0051168	nuclear export

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.34	GO:0003677	DNA binding
0.32	GO:0016874	ligase activity

0.55	GO:0005730	nucleolus
0.53	GO:0005654	nucleoplasm
0.39	GO:0030425	dendrite
0.33	GO:0042405	nuclear inclusion body
0.33	GO:0016363	nuclear matrix
0.33	GO:0005737	cytoplasm
0.32	GO:0043234	protein complex

0.32

GO:0016874

sp|P0C7T7|FMAS1_HUMAN
Putative uncharacterized protein FRMD6-AS1
Search

sp|P0C7T8|TM253_HUMAN
Transmembrane protein 253
Search

TMEM253

0.47	Transmembrane protein 253

0.36	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0065009	regulation of molecular function

0.36

GO:0005089

Rho guanyl-nucleotide exchange factor activity

0.30

GO:0044425

membrane part

sp|P0C7U0|ELFN1_HUMAN
Protein ELFN1
Search

0.95	Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1

0.67	GO:0010923	negative regulation of phosphatase activity
0.60	GO:0050808	synapse organization

0.40

GO:0019902

phosphatase binding

0.64	GO:0060076	excitatory synapse
0.59	GO:0030425	dendrite
0.39	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.30	GO:0044425	membrane part

sp|P0C7U1|ASA2B_HUMAN
Putative inactive neutral ceramidase B
Search

0.72	Putative inactive neutral ceramidase B

0.53	GO:0006665	sphingolipid metabolic process
0.50	GO:0006915	apoptotic process
0.44	GO:0010033	response to organic substance
0.42	GO:0008283	cell proliferation
0.40	GO:0043603	cellular amide metabolic process
0.38	GO:0007165	signal transduction
0.38	GO:0007275	multicellular organism development

0.60

GO:0017040

ceramidase activity

0.43	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.40	GO:0045177	apical part of cell
0.38	GO:0000139	Golgi membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.60

EC:3.5.1.23

GO:0017040

sp|P0C7U3|ZH11B_HUMAN
Probable palmitoyltransferase ZDHHC11B
Search

0.49	Palmitoyltransferase

0.38	GO:0018345	protein palmitoylation
0.36	GO:0001578	microtubule bundle formation
0.36	GO:0046785	microtubule polymerization
0.35	GO:0002943	tRNA dihydrouridine synthesis
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0006897	endocytosis

0.78	GO:0019707	protein-cysteine S-acyltransferase activity
0.77	GO:0016409	palmitoyltransferase activity
0.35	GO:0015631	tubulin binding
0.35	GO:0017150	tRNA dihydrouridine synthase activity
0.34	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0016788	hydrolase activity, acting on ester bonds

0.40	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.78

EC:2.3.1

GO:0019707

sp|P0C7U9|FA87A_HUMAN
Protein FAM87A
Search

sp|P0C7V0|CF217_HUMAN
Putative uncharacterized protein encoded by LINC00271
Search

sp|P0C7V4|F90AJ_HUMAN
Putative protein FAM90A15P
Search

0.45	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0000128	flocculation

0.59	GO:0005515	protein binding
0.49	GO:0016503	pheromone receptor activity

0.30

GO:0044425

membrane part

sp|P0C7V6|SP202_HUMAN
Putative transcription factor SPT20 homolog-like 2
Search

SUPT20H

0.92	Suppressor of Ty 20

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:0045722	positive regulation of gluconeogenesis
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0010628	positive regulation of gene expression
0.38	GO:0007369	gastrulation
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0006914	autophagy

0.76	GO:0003712	transcription cofactor activity
0.33	GO:0005515	protein binding

0.80	GO:0000124	SAGA complex
0.50	GO:0001650	fibrillar center
0.36	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P0C7V7|SC11B_HUMAN
Putative signal peptidase complex catalytic subunit SEC11B
Search

SEC11A

0.72	Signal peptidase complex catalytic subunit SEC11

0.80

GO:0006465

signal peptide processing

0.67

GO:0008236

serine-type peptidase activity

0.82	GO:0005787	signal peptidase complex
0.36	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P0C7V8|DC8L2_HUMAN
DDB1- and CUL4-associated factor 8-like protein 2
Search

DCAF8

0.87	DDB1 and CUL4 associated factor 8 like 2

0.65	GO:0016567	protein ubiquitination
0.52	GO:0043687	post-translational protein modification

0.44

GO:0005515

protein binding

0.75	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.61	GO:0005634	nucleus
0.53	GO:0005829	cytosol
0.52	GO:0031974	membrane-enclosed lumen
0.48	GO:0005739	mitochondrion
0.46	GO:0044446	intracellular organelle part

sp|P0C7V9|ME15P_HUMAN
Putative methyltransferase-like protein 15P1
Search

METTL15

0.74	Methyltransferase like 15

0.63	GO:0032259	methylation
0.48	GO:0000154	rRNA modification
0.38	GO:0044260	cellular macromolecule metabolic process
0.32	GO:0055114	oxidation-reduction process

0.63	GO:0008168	methyltransferase activity
0.49	GO:0140102	catalytic activity, acting on a rRNA
0.34	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.63

GO:0008168

sp|P0C7W0|PRR29_HUMAN
Proline-rich protein 29
Search

PRR29

0.97	Proline-rich protein 29

sp|P0C7W6|CC172_HUMAN
Coiled-coil domain-containing protein 172
Search

CCDC172

0.97	Coiled-coil domain-containing protein 172

0.37

GO:0005515

protein binding

0.53	GO:0097225	sperm midpiece
0.49	GO:0005737	cytoplasm

sp|P0C7W8|F90AD_HUMAN
Putative protein FAM90A13P
Search

0.45	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0000128	flocculation

0.59	GO:0005515	protein binding
0.49	GO:0016503	pheromone receptor activity

0.30

GO:0044425

membrane part

sp|P0C7W9|F90AE_HUMAN
Putative protein FAM90A14P
Search

0.45	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0000128	flocculation

0.59	GO:0005515	protein binding
0.49	GO:0016503	pheromone receptor activity

0.30

GO:0044425

membrane part

sp|P0C7X0|F90AO_HUMAN
Putative protein FAM90A24P
Search

sp|P0C7X1|TBC3H_HUMAN
TBC1 domain family member 3H
Search

0.97	TBC1 domain family member 3

0.85	GO:0031338	regulation of vesicle fusion
0.84	GO:0090630	activation of GTPase activity
0.69	GO:0006886	intracellular protein transport
0.47	GO:1902017	regulation of cilium assembly

0.81	GO:0017137	Rab GTPase binding
0.76	GO:0005096	GTPase activator activity

0.67	GO:0012505	endomembrane system
0.54	GO:0005886	plasma membrane
0.45	GO:0005622	intracellular
0.42	GO:0031982	vesicle
0.42	GO:0098805	whole membrane
0.42	GO:0098588	bounding membrane of organelle

sp|P0C7X2|ZN688_HUMAN
Zinc finger protein 688
Search

ZNF688

0.95	Zinc finger protein 688

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.46	GO:0035914	skeletal muscle cell differentiation
0.35	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle

sp|P0C7X3|CCYL3_HUMAN
Putative cyclin-Y-like protein 3
Search

0.79	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.50	GO:0030317	flagellated sperm motility
0.48	GO:0007283	spermatogenesis
0.34	GO:0048312	intracellular distribution of mitochondria

0.77	GO:0019901	protein kinase binding
0.32	GO:0003729	mRNA binding

0.39	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P0C7X4|FHL19_HUMAN
Putative ferritin heavy polypeptide-like 19
Search

0.56	Ferritin heavy chain B

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.53	GO:0051238	sequestering of metal ion
0.50	GO:1904229	regulation of succinate dehydrogenase activity
0.50	GO:1904234	positive regulation of aconitate hydratase activity
0.50	GO:0051651	maintenance of location in cell
0.47	GO:0051353	positive regulation of oxidoreductase activity
0.45	GO:0042127	regulation of cell proliferation
0.42	GO:0048522	positive regulation of cellular process
0.39	GO:0055114	oxidation-reduction process

0.76	GO:0008199	ferric iron binding
0.48	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.33	GO:0042802	identical protein binding

0.42	GO:0005739	mitochondrion
0.37	GO:0044754	autolysosome
0.36	GO:0071682	endocytic vesicle lumen
0.35	GO:0070288	ferritin complex
0.33	GO:0005576	extracellular region
0.33	GO:0005634	nucleus

0.48

EC:1.16.3

GO:0016724

sp|P0C7X5|ZN806_HUMAN
Zinc finger protein 806
Search

0.84	Zinc finger protein 806

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.43	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0006351	transcription, DNA-templated
0.38	GO:0007576	nucleolar fragmentation
0.37	GO:0051593	response to folic acid
0.37	GO:0070895	negative regulation of transposon integration
0.36	GO:0007275	multicellular organism development

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding
0.35	GO:0003682	chromatin binding

0.46	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0015629	actin cytoskeleton
0.42	GO:0044446	intracellular organelle part
0.39	GO:0017053	transcriptional repressor complex
0.37	GO:0012505	endomembrane system
0.36	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.34	GO:0005829	cytosol

sp|P0C838|ERAS1_HUMAN
Putative uncharacterized protein encoded by ERICH1-AS1
Search

sp|P0C841|FA66E_HUMAN
Putative protein FAM66E
Search

sp|P0C842|CJ052_HUMAN
Putative uncharacterized protein encoded by LINC00614
Search

0.42	GO:0055114	oxidation-reduction process
0.36	GO:0001676	long-chain fatty acid metabolic process
0.36	GO:0009058	biosynthetic process

0.67	GO:0031177	phosphopantetheine binding
0.48	GO:0016740	transferase activity
0.43	GO:0016491	oxidoreductase activity
0.39	GO:0016788	hydrolase activity, acting on ester bonds
0.38	GO:0019171	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
0.38	GO:0008270	zinc ion binding
0.36	GO:0030170	pyridoxal phosphate binding
0.36	GO:0102391	decanoate--CoA ligase activity
0.36	GO:0004467	long-chain fatty acid-CoA ligase activity
0.35	GO:0050157	ornithine racemase activity

0.30

GO:0016020

membrane

0.48

GO:0016740

sp|P0C843|CI014_HUMAN
Putative uncharacterized protein encoded by LINC00032
Search

sp|P0C851|PIRT_HUMAN
Phosphoinositide-interacting protein
Search

PIRT

0.97	Phosphoinositide-interacting protein (Fragment)

0.47	GO:0048266	behavioral response to pain
0.46	GO:2001259	positive regulation of cation channel activity
0.45	GO:0048015	phosphatidylinositol-mediated signaling
0.43	GO:0009408	response to heat

0.46	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.46	GO:0044325	ion channel binding
0.45	GO:1902936	phosphatidylinositol bisphosphate binding

0.38	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|P0C853|BAAS2_HUMAN
Putative uncharacterized protein BAALC-AS2
Search

sp|P0C854|CECR9_HUMAN
Putative cat eye syndrome critical region protein 9
Search

0.30	Putative cat eye syndrome critical region protein 9

0.66

GO:0005576

extracellular region

sp|P0C860|MS3L2_HUMAN
Putative male-specific lethal-3 protein-like 2
Search

MSL3

0.94	Putative dosage compensation regulatory complex/histone acetyltransferase complex subunit

0.74	GO:0016569	covalent chromatin modification
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0018393	internal peptidyl-lysine acetylation
0.45	GO:0006476	protein deacetylation
0.45	GO:0006338	chromatin remodeling
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0006412	translation

0.55	GO:0003677	DNA binding
0.53	GO:0140034	methylation-dependent protein binding
0.51	GO:0042393	histone binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016740	transferase activity

0.85	GO:0072487	MSL complex
0.46	GO:0035267	NuA4 histone acetyltransferase complex
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.32

GO:0016740

sp|P0C862|C1T9A_HUMAN
Complement C1q and tumor necrosis factor-related protein 9A
Search

0.75	Mitochondrial intermediate peptidase

0.38	GO:0001867	complement activation, lectin pathway
0.37	GO:0010469	regulation of receptor activity
0.34	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0035848	oviduct morphogenesis
0.33	GO:0009405	pathogenesis
0.33	GO:0048621	post-embryonic digestive tract morphogenesis
0.33	GO:0060729	intestinal epithelial structure maintenance
0.33	GO:0007155	cell adhesion
0.33	GO:0055013	cardiac muscle cell development
0.33	GO:0016539	intein-mediated protein splicing

0.40	GO:0005201	extracellular matrix structural constituent
0.38	GO:0005537	mannose binding
0.37	GO:0005515	protein binding
0.37	GO:0030545	receptor regulator activity
0.33	GO:0008201	heparin binding
0.32	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.32	GO:0042302	structural constituent of cuticle
0.32	GO:0005509	calcium ion binding
0.31	GO:0016301	kinase activity

0.76	GO:0005581	collagen trimer
0.64	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.33	GO:0005938	cell cortex
0.33	GO:0019867	outer membrane
0.32	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.32	GO:0099512	supramolecular fiber
0.30	GO:0016021	integral component of membrane

sp|P0C864|DANCR_HUMAN
Putative uncharacterized protein DANCR
Search

sp|P0C866|F91A2_HUMAN
Putative uncharacterized protein encoded by LINC00869
Search

sp|P0C869|PA24B_HUMAN
Cytosolic phospholipase A2 beta
Search

0.65	Cytosolic phospholipase A2 delta

0.80	GO:0009395	phospholipid catabolic process
0.51	GO:0046503	glycerolipid catabolic process
0.46	GO:0006650	glycerophospholipid metabolic process
0.40	GO:0006690	icosanoid metabolic process
0.40	GO:0033559	unsaturated fatty acid metabolic process
0.39	GO:0071236	cellular response to antibiotic
0.38	GO:1901570	fatty acid derivative biosynthetic process
0.38	GO:0071310	cellular response to organic substance
0.38	GO:0050482	arachidonic acid secretion
0.37	GO:0014070	response to organic cyclic compound

0.82	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.82	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.79	GO:0004623	phospholipase A2 activity
0.52	GO:0046872	metal ion binding
0.44	GO:0004622	lysophospholipase activity
0.38	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.36	GO:0005544	calcium-dependent phospholipid binding

0.48	GO:0005737	cytoplasm
0.39	GO:0031982	vesicle
0.38	GO:0032587	ruffle membrane
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0044446	intracellular organelle part
0.34	GO:0012505	endomembrane system
0.34	GO:0005576	extracellular region
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0031975	envelope

0.79

EC:3.1.1.4

GO:0004623

sp|P0C870|JMJD7_HUMAN
JmjC domain-containing protein 7
Search

JMJD7

0.73	JmjC domain-containing protein 7

0.72	GO:0009395	phospholipid catabolic process
0.38	GO:0045454	cell redox homeostasis

0.76	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.76	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.73	GO:0004623	phospholipase A2 activity
0.50	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding

0.47

GO:0005737

cytoplasm

0.73

EC:3.1.1.4

GO:0004623

sp|P0C874|S31D3_HUMAN
Putative spermatogenesis-associated protein 31D3
Search

0.95	Putative spermatogenesis-associated protein 31D3

0.50	GO:0007283	spermatogenesis
0.46	GO:0030154	cell differentiation
0.33	GO:0006468	protein phosphorylation

0.33	GO:0003779	actin binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0043160	acrosomal lumen
0.35	GO:0002080	acrosomal membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C875|F228B_HUMAN
Protein FAM228B
Search

0.44	Peptidylprolyl isomerase

0.72

GO:0000413

protein peptidyl-prolyl isomerization

0.72

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

0.72

GO:0003755

sp|P0C879|YJ018_HUMAN
Putative uncharacterized protein FLJ43185
Search

sp|P0C880|YT014_HUMAN
Putative uncharacterized protein FLJ40606
Search

sp|P0C881|R10B1_HUMAN
Radial spoke head 10 homolog B
Search

RSPH10B

0.95	LOW QUALITY PROTEIN: radial spoke head 10 homolog B

0.57	GO:0006298	mismatch repair
0.47	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.42	GO:0016310	phosphorylation
0.38	GO:0046488	phosphatidylinositol metabolic process
0.38	GO:0030258	lipid modification
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0006289	nucleotide-excision repair
0.34	GO:0032508	DNA duplex unwinding
0.34	GO:0010467	gene expression

0.55	GO:0030983	mismatched DNA binding
0.48	GO:0004519	endonuclease activity
0.46	GO:0032559	adenyl ribonucleotide binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0016301	kinase activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0004003	ATP-dependent DNA helicase activity
0.33	GO:0140096	catalytic activity, acting on a protein

0.35	GO:0005840	ribosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.37

GO:0016773

sp|P0C8F1|PATE4_HUMAN
Prostate and testis expressed protein 4
Search

PATE4

0.97	Prostate and testis expressed protein 4

0.85

GO:0099601

regulation of neurotransmitter receptor activity

0.86

GO:0099602

neurotransmitter receptor regulator activity

0.84	GO:0001669	acrosomal vesicle
0.73	GO:0005615	extracellular space

sp|P0CAP1|MYZAP_HUMAN
Myocardial zonula adherens protein
Search

MYZAP

0.96	myocardial zonula adherens protein isoform X1

0.63	GO:0035556	intracellular signal transduction
0.40	GO:0060047	heart contraction

0.37

GO:0005515

protein binding

0.50	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.49	GO:0031674	I band
0.48	GO:0030864	cortical actin cytoskeleton
0.42	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0030054	cell junction

sp|P0CAP2|GRL1A_HUMAN
DNA-directed RNA polymerase II subunit GRINL1A
Search

POLR2M

0.96	RNA polymerase II subunit M

0.60	GO:0051685	maintenance of ER location
0.44	GO:0035556	intracellular signal transduction
0.42	GO:0032774	RNA biosynthetic process
0.36	GO:0060047	heart contraction

0.48

GO:0003899

DNA-directed 5'-3' RNA polymerase activity

0.76	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.51	GO:0043025	neuronal cell body
0.48	GO:0005635	nuclear envelope
0.40	GO:0031674	I band
0.40	GO:0030864	cortical actin cytoskeleton

0.48

EC:2.7.7.6

GO:0003899

sp|P0CAT3|TLXNB_HUMAN
Putative TLX1 neighbor protein
Search

sp|P0CB33|ZN735_HUMAN
Putative zinc finger protein 735
Search

ZNF195

0.76	Zinc finger protein 479

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.39	GO:0035108	limb morphogenesis
0.39	GO:0070895	negative regulation of transposon integration
0.38	GO:0006351	transcription, DNA-templated
0.36	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.39	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|P0CB38|PAB4L_HUMAN
Polyadenylate-binding protein 4-like
Search

0.51	Polyadenylate-binding protein 4

0.53	GO:0061515	myeloid cell development
0.52	GO:0043488	regulation of mRNA stability
0.36	GO:0000413	protein peptidyl-prolyl isomerization
0.34	GO:0006457	protein folding
0.34	GO:0007596	blood coagulation
0.34	GO:0006401	RNA catabolic process
0.33	GO:0006396	RNA processing
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.37	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0005515	protein binding

0.51	GO:0010494	cytoplasmic stress granule
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.37

GO:0003755

sp|P0CB47|UBFL1_HUMAN
Upstream-binding factor 1-like protein 1
Search

UBTFL1

0.96	Upstream binding transcription factor, RNA polymerase I-like 1

0.40	GO:0006360	transcription by RNA polymerase I
0.39	GO:0045943	positive regulation of transcription by RNA polymerase I
0.38	GO:0007275	multicellular organism development
0.37	GO:0006325	chromatin organization
0.37	GO:1990830	cellular response to leukemia inhibitory factor
0.36	GO:0045814	negative regulation of gene expression, epigenetic
0.36	GO:0007565	female pregnancy
0.36	GO:0098656	anion transmembrane transport
0.36	GO:0006354	DNA-templated transcription, elongation
0.36	GO:0016458	gene silencing

0.55	GO:0003677	DNA binding
0.41	GO:0097110	scaffold protein binding
0.39	GO:0003682	chromatin binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0005452	inorganic anion exchanger activity
0.36	GO:0003713	transcription coactivator activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0003723	RNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.61	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0031248	protein acetyltransferase complex
0.35	GO:1905368	peptidase complex
0.34	GO:0005737	cytoplasm
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P0CB48|UBFL6_HUMAN
Putative upstream-binding factor 1-like protein 6
Search

0.92	Nucleolar transcription factor 1

0.44	GO:0006360	transcription by RNA polymerase I
0.39	GO:0045943	positive regulation of transcription by RNA polymerase I
0.36	GO:0000183	chromatin silencing at rDNA
0.36	GO:1990830	cellular response to leukemia inhibitory factor
0.36	GO:0007275	multicellular organism development
0.36	GO:0006354	DNA-templated transcription, elongation
0.35	GO:1902659	regulation of glucose mediated signaling pathway
0.35	GO:0016578	histone deubiquitination

0.55	GO:0003677	DNA binding
0.46	GO:0097110	scaffold protein binding
0.43	GO:0003682	chromatin binding
0.43	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.34	GO:1902493	acetyltransferase complex
0.34	GO:1905368	peptidase complex
0.33	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P0CE67|CC079_HUMAN
Putative uncharacterized protein C3orf79
Search

sp|P0CE71|OCM2_HUMAN
Putative oncomodulin-2
Search

0.97	Oncomodulin

0.39	GO:1905591	regulation of optical nerve axon regeneration
0.38	GO:1902336	positive regulation of retinal ganglion cell axon guidance
0.38	GO:0048687	positive regulation of sprouting of injured axon
0.38	GO:0048690	regulation of axon extension involved in regeneration
0.37	GO:0070207	protein homotrimerization
0.37	GO:0045773	positive regulation of axon extension
0.37	GO:0051289	protein homotetramerization
0.36	GO:0051480	regulation of cytosolic calcium ion concentration
0.36	GO:0009611	response to wounding
0.34	GO:0010941	regulation of cell death

0.70	GO:0005509	calcium ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.41	GO:0030424	axon
0.35	GO:0005615	extracellular space
0.35	GO:0099512	supramolecular fiber
0.35	GO:0031982	vesicle
0.35	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.34	GO:0043234	protein complex

sp|P0CE72|ONCO_HUMAN
Oncomodulin-1
Search

0.97	Oncomodulin

0.39	GO:1905591	regulation of optical nerve axon regeneration
0.38	GO:1902336	positive regulation of retinal ganglion cell axon guidance
0.38	GO:0048687	positive regulation of sprouting of injured axon
0.38	GO:0048690	regulation of axon extension involved in regeneration
0.37	GO:0070207	protein homotrimerization
0.37	GO:0045773	positive regulation of axon extension
0.37	GO:0051289	protein homotetramerization
0.36	GO:0051480	regulation of cytosolic calcium ion concentration
0.36	GO:0009611	response to wounding
0.34	GO:0010941	regulation of cell death

0.70	GO:0005509	calcium ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.41	GO:0030424	axon
0.35	GO:0005615	extracellular space
0.35	GO:0099512	supramolecular fiber
0.35	GO:0031982	vesicle
0.35	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.34	GO:0043234	protein complex

sp|P0CF51|TRGC1_HUMAN
T-cell receptor gamma chain C region 1
Search

0.97	T-cell receptor gamma chain C region 1

0.46	GO:0006955	immune response
0.41	GO:0007165	signal transduction

0.45	GO:0099600	transmembrane receptor activity
0.43	GO:0038023	signaling receptor activity

0.44

GO:0005887

integral component of plasma membrane

sp|P0CF74|IGLC6_HUMAN
Immunoglobulin lambda constant 6
Search

0.97	Ig lambda chain C regions

0.75	GO:0006910	phagocytosis, recognition
0.74	GO:0002250	adaptive immune response
0.74	GO:0006911	phagocytosis, engulfment
0.74	GO:0050853	B cell receptor signaling pathway
0.73	GO:0050871	positive regulation of B cell activation
0.72	GO:0002449	lymphocyte mediated immunity
0.72	GO:0006956	complement activation
0.68	GO:0045087	innate immune response
0.67	GO:0042742	defense response to bacterium
0.50	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.79	GO:0003823	antigen binding
0.75	GO:0034987	immunoglobulin receptor binding
0.43	GO:0004252	serine-type endopeptidase activity

0.76	GO:0072562	blood microparticle
0.75	GO:0042571	immunoglobulin complex, circulating
0.70	GO:0009897	external side of plasma membrane
0.51	GO:0070062	extracellular exosome

0.43

GO:0004252

sp|P0CF75|EBLN1_HUMAN
Endogenous Bornavirus-like nucleoprotein 1
Search

0.37	Endogenous Bornavirus like nucleoprotein 1

0.41	GO:0019055	modification by virus of host cell cycle regulation
0.41	GO:0039592	suppression by virus of G2/M transition of host mitotic cell cycle
0.40	GO:1902594	multi-organism nuclear import
0.39	GO:0075733	intracellular transport of virus
0.39	GO:0039644	suppression by virus of host NF-kappaB transcription factor activity
0.38	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.38	GO:0044409	entry into host

0.70	GO:0019013	viral nucleocapsid
0.40	GO:0019029	helical viral capsid
0.38	GO:0042025	host cell nucleus
0.36	GO:0030430	host cell cytoplasm
0.30	GO:0016020	membrane

sp|P0CF97|F200B_HUMAN
Protein FAM200B
Search

0.16	SCAN domain-containing protein 3

0.54	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0015074	DNA integration
0.40	GO:0007010	cytoskeleton organization
0.39	GO:0007275	multicellular organism development
0.39	GO:0022604	regulation of cell morphogenesis

0.55	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.48	GO:0008270	zinc ion binding
0.46	GO:0003676	nucleic acid binding
0.39	GO:0005515	protein binding

0.53	GO:0005654	nucleoplasm
0.41	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0CG00|ZSA5D_HUMAN
Putative zinc finger and SCAN domain-containing protein 5D
Search

0.95	Zinc finger and SCAN domain-containing protein 5A

0.52	GO:2001141	regulation of RNA biosynthetic process
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.50	GO:0006351	transcription, DNA-templated
0.41	GO:0030098	lymphocyte differentiation
0.41	GO:0051291	protein heterooligomerization
0.41	GO:0030218	erythrocyte differentiation
0.37	GO:0051254	positive regulation of RNA metabolic process
0.37	GO:0010557	positive regulation of macromolecule biosynthetic process
0.37	GO:0031328	positive regulation of cellular biosynthetic process

0.54	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.39	GO:0019904	protein domain specific binding
0.33	GO:0001223	transcription coactivator binding
0.32	GO:0042393	histone binding
0.32	GO:0046982	protein heterodimerization activity

0.54	GO:0005634	nucleus
0.41	GO:0005721	pericentric heterochromatin
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0043234	protein complex
0.33	GO:0070062	extracellular exosome
0.32	GO:0098636	protein complex involved in cell adhesion
0.32	GO:0098802	plasma membrane receptor complex
0.32	GO:0032993	protein-DNA complex
0.32	GO:0015630	microtubule cytoskeleton
0.32	GO:0005829	cytosol

sp|P0CG01|GKN3_HUMAN
Gastrokine-3
Search

GKN3

0.87	Gastrokine-3

0.77

GO:0050680

negative regulation of epithelial cell proliferation

0.72	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|P0CG04|IGLC1_HUMAN
Immunoglobulin lambda constant 1
Search

0.97	Ig lambda chain C regions

0.75	GO:0006910	phagocytosis, recognition
0.75	GO:0002250	adaptive immune response
0.74	GO:0006911	phagocytosis, engulfment
0.74	GO:0050853	B cell receptor signaling pathway
0.73	GO:0050871	positive regulation of B cell activation
0.72	GO:0002449	lymphocyte mediated immunity
0.72	GO:0006956	complement activation
0.68	GO:0045087	innate immune response
0.67	GO:0042742	defense response to bacterium
0.51	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.80	GO:0003823	antigen binding
0.76	GO:0034987	immunoglobulin receptor binding
0.43	GO:0004252	serine-type endopeptidase activity

0.77	GO:0072562	blood microparticle
0.75	GO:0042571	immunoglobulin complex, circulating
0.70	GO:0009897	external side of plasma membrane
0.52	GO:0070062	extracellular exosome

0.43

GO:0004252

sp|P0CG08|GPHRB_HUMAN
Golgi pH regulator B
Search

0.80	Golgi pH regulator A

0.52	GO:0043588	skin development
0.50	GO:0051452	intracellular pH reduction
0.44	GO:0098656	anion transmembrane transport
0.41	GO:0034765	regulation of ion transmembrane transport
0.38	GO:0015031	protein transport
0.36	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0007154	cell communication
0.34	GO:0023052	signaling
0.34	GO:0051716	cellular response to stimulus

0.47	GO:0008308	voltage-gated anion channel activity
0.34	GO:0004871	signal transducer activity

0.48	GO:0032580	Golgi cisterna membrane
0.39	GO:0030660	Golgi-associated vesicle membrane
0.35	GO:0005922	connexin complex
0.30	GO:0031224	intrinsic component of membrane

sp|P0CG12|CTF8A_HUMAN
Chromosome transmission fidelity protein 8 homolog isoform 2
Search

0.61	Putative vesicle coat complex copii subunit sfb3

sp|P0CG20|PRR35_HUMAN
Proline-rich protein 35
Search

PRR35

0.97	NHL-repeat-containing protein 4

0.74	GO:0008544	epidermis development
0.68	GO:0006366	transcription by RNA polymerase II
0.68	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0006506	GPI anchor biosynthetic process
0.47	GO:0016567	protein ubiquitination
0.44	GO:0030154	cell differentiation
0.43	GO:0035556	intracellular signal transduction

0.78	GO:1990841	promoter-specific chromatin binding
0.75	GO:0001046	core promoter sequence-specific DNA binding
0.73	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.45	GO:0003924	GTPase activity
0.45	GO:0032550	purine ribonucleoside binding
0.44	GO:0019001	guanyl nucleotide binding
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0046872	metal ion binding

0.56	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.52

EC:2.4.1.198

GO:0017176

sp|P0CG21|NHLC4_HUMAN
NHL-repeat-containing protein 4
Search

NHLRC4

0.97	LOW QUALITY PROTEIN: NHL-repeat-containing protein 4

0.52

GO:0006506

GPI anchor biosynthetic process

0.55

GO:0017176

phosphatidylinositol N-acetylglucosaminyltransferase activity

0.30

GO:0031224

intrinsic component of membrane

0.55

EC:2.4.1.198

GO:0017176

sp|P0CG22|DR4L1_HUMAN
Putative dehydrogenase/reductase SDR family member 4-like 1
Search

0.84	Dehydrogenase/reductase SDR family member 4

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0042574	retinal metabolic process
0.44	GO:0008202	steroid metabolic process
0.44	GO:0051262	protein tetramerization
0.43	GO:0043011	myeloid dendritic cell differentiation
0.42	GO:0006066	alcohol metabolic process
0.42	GO:0042180	cellular ketone metabolic process
0.41	GO:0043066	negative regulation of apoptotic process
0.40	GO:0034599	cellular response to oxidative stress
0.39	GO:0034754	cellular hormone metabolic process

0.57	GO:0004090	carbonyl reductase (NADPH) activity
0.52	GO:0001758	retinal dehydrogenase activity
0.49	GO:0000253	3-keto sterol reductase activity
0.49	GO:0018455	alcohol dehydrogenase [NAD(P)+] activity
0.42	GO:0005102	receptor binding
0.41	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.39	GO:0052650	NADP-retinol dehydrogenase activity
0.36	GO:0042802	identical protein binding

0.53	GO:0005777	peroxisome
0.45	GO:0005739	mitochondrion
0.44	GO:0031903	microbody membrane
0.42	GO:0070062	extracellular exosome
0.40	GO:0005635	nuclear envelope
0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.57	EC:1.1.1.184	GO:0004090
0.39	KEGG:R08379	GO:0052650

sp|P0CG23|ZN853_HUMAN
Zinc finger protein 853
Search

ZNF853

0.97	Zinc finger protein 853

0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.35	GO:0043547	positive regulation of GTPase activity
0.35	GO:1900112	regulation of histone H3-K9 trimethylation
0.33	GO:0016070	RNA metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0042254	ribosome biogenesis
0.33	GO:0032259	methylation
0.33	GO:0007018	microtubule-based movement

0.50	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005096	GTPase activator activity
0.34	GO:0042802	identical protein binding
0.34	GO:0003682	chromatin binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0003779	actin binding

0.36	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.33	GO:0032991	macromolecular complex
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

0.33

GO:0008168

sp|P0CG24|ZN883_HUMAN
Zinc finger protein 883
Search

0.54	Zinc finger protein 2

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.38	GO:0045321	leukocyte activation
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0030154	cell differentiation
0.36	GO:0007275	multicellular organism development

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0042802	identical protein binding
0.43	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle

sp|P0CG29|GST2_HUMAN
Glutathione S-transferase theta-2
Search

0.82	Glutathione S-transferase theta-2

0.53	GO:0006749	glutathione metabolic process
0.46	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:1901687	glutathione derivative biosynthetic process
0.37	GO:0009751	response to salicylic acid
0.36	GO:0098869	cellular oxidant detoxification
0.36	GO:0018900	dichloromethane metabolic process
0.35	GO:0033197	response to vitamin E
0.35	GO:0006336	DNA replication-independent nucleosome assembly
0.35	GO:0010269	response to selenium ion
0.34	GO:0006304	DNA modification

0.55	GO:0004364	glutathione transferase activity
0.38	GO:0004602	glutathione peroxidase activity
0.36	GO:0047651	alkylhalidase activity
0.33	GO:0004386	helicase activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.44	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.41	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

0.55	EC:2.5.1.18	GO:0004364
0.36	KEGG:R03523	GO:0047651

sp|P0CG30|GSTT2_HUMAN
Glutathione S-transferase theta-2B
Search

0.82	Glutathione S-transferase theta-2

0.53	GO:0006749	glutathione metabolic process
0.46	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:1901687	glutathione derivative biosynthetic process
0.37	GO:0009751	response to salicylic acid
0.36	GO:0098869	cellular oxidant detoxification
0.36	GO:0018900	dichloromethane metabolic process
0.35	GO:0033197	response to vitamin E
0.35	GO:0006336	DNA replication-independent nucleosome assembly
0.35	GO:0010269	response to selenium ion
0.34	GO:0006304	DNA modification

0.55	GO:0004364	glutathione transferase activity
0.38	GO:0004602	glutathione peroxidase activity
0.36	GO:0047651	alkylhalidase activity
0.33	GO:0004386	helicase activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.44	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.41	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

0.55	EC:2.5.1.18	GO:0004364
0.36	KEGG:R03523	GO:0047651

sp|P0CG31|Z286B_HUMAN
Putative zinc finger protein 286B
Search

ZNF329

0.75	Zinc finger protein 329

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.44	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.44	GO:0002437	inflammatory response to antigenic stimulus
0.38	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0007275	multicellular organism development

0.51	GO:0003676	nucleic acid binding
0.48	GO:0046872	metal ion binding
0.43	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding

0.42	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P0CG32|ZCC18_HUMAN
Zinc finger CCHC domain-containing protein 18
Search

0.75	GO:0030509	BMP signaling pathway
0.50	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity
0.43	GO:0006351	transcription, DNA-templated
0.35	GO:0055085	transmembrane transport

0.76	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.57	GO:0008270	zinc ion binding
0.48	GO:0032183	SUMO binding
0.47	GO:0003676	nucleic acid binding

0.72	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

sp|P0CG33|GOG6D_HUMAN
Golgin subfamily A member 6D
Search

0.89	Golgin subfamily A member 6D

0.34	GO:0090166	Golgi disassembly
0.34	GO:0060050	positive regulation of protein glycosylation
0.34	GO:0090161	Golgi ribbon formation
0.34	GO:0090306	spindle assembly involved in meiosis
0.33	GO:0008356	asymmetric cell division
0.33	GO:0048208	COPII vesicle coating
0.33	GO:0051289	protein homotetramerization
0.33	GO:0032091	negative regulation of protein binding
0.33	GO:0090307	mitotic spindle assembly
0.33	GO:1904668	positive regulation of ubiquitin protein ligase activity

0.37

GO:0005515

protein binding

0.72	GO:0005794	Golgi apparatus
0.37	GO:0005801	cis-Golgi network
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.35	GO:0005829	cytosol
0.33	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0072686	mitotic spindle
0.33	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.33	GO:0000922	spindle pole
0.33	GO:0005874	microtubule

sp|P0CG34|TB15A_HUMAN
Thymosin beta-15A
Search

0.95	thymosin beta-b

0.75	GO:0007015	actin filament organization
0.40	GO:0042989	sequestering of actin monomers
0.39	GO:0051497	negative regulation of stress fiber assembly
0.39	GO:0030335	positive regulation of cell migration

0.85

GO:0003785

actin monomer binding

0.41	GO:0005856	cytoskeleton
0.37	GO:0099512	supramolecular fiber
0.35	GO:0043234	protein complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0CG35|TB15B_HUMAN
Thymosin beta-15B
Search

0.95	thymosin beta-b

0.75	GO:0007015	actin filament organization
0.40	GO:0042989	sequestering of actin monomers
0.39	GO:0051497	negative regulation of stress fiber assembly
0.39	GO:0030335	positive regulation of cell migration

0.85

GO:0003785

actin monomer binding

0.41	GO:0005856	cytoskeleton
0.37	GO:0099512	supramolecular fiber
0.35	GO:0043234	protein complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0CG36|CFC1B_HUMAN
Cryptic family protein 1B
Search

0.97	Cripto, FRL-1, cryptic family 1

0.74	GO:0038092	nodal signaling pathway
0.74	GO:0007369	gastrulation
0.68	GO:0007368	determination of left/right symmetry
0.61	GO:0060460	left lung morphogenesis
0.58	GO:0060413	atrial septum morphogenesis
0.57	GO:0048536	spleen development
0.57	GO:0060976	coronary vasculature development
0.56	GO:0048546	digestive tract morphogenesis
0.56	GO:0007492	endoderm development
0.56	GO:0003143	embryonic heart tube morphogenesis

0.72	GO:0038100	nodal binding
0.60	GO:0070697	activin receptor binding

0.62	GO:0031225	anchored component of membrane
0.60	GO:0005576	extracellular region
0.46	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P0CG37|CFC1_HUMAN
Cryptic protein
Search

0.96	Cripto, FRL-1, cryptic family 1

0.74	GO:0038092	nodal signaling pathway
0.74	GO:0007369	gastrulation
0.68	GO:0007368	determination of left/right symmetry
0.61	GO:0060460	left lung morphogenesis
0.58	GO:0060413	atrial septum morphogenesis
0.57	GO:0048536	spleen development
0.57	GO:0060976	coronary vasculature development
0.56	GO:0048546	digestive tract morphogenesis
0.56	GO:0007492	endoderm development
0.56	GO:0003143	embryonic heart tube morphogenesis

0.72	GO:0038100	nodal binding
0.60	GO:0070697	activin receptor binding

0.62	GO:0031225	anchored component of membrane
0.60	GO:0005576	extracellular region
0.46	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P0CG38|POTEI_HUMAN
POTE ankyrin domain family member I
Search

0.10	POTE ankyrin domain family member I

0.41	GO:0036213	contractile ring contraction
0.41	GO:0000011	vacuole inheritance
0.41	GO:1903475	mitotic actomyosin contractile ring assembly
0.40	GO:0071963	establishment or maintenance of cell polarity regulating cell shape
0.40	GO:0030476	ascospore wall assembly
0.40	GO:0060303	regulation of nucleosome density
0.40	GO:0001300	chronological cell aging
0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0043486	histone exchange
0.40	GO:0030010	establishment of cell polarity

0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.41	GO:0005200	structural constituent of cytoskeleton
0.39	GO:0004402	histone acetyltransferase activity
0.38	GO:0042802	identical protein binding
0.37	GO:0017022	myosin binding
0.36	GO:0004424	imidazoleglycerol-phosphate dehydratase activity

0.41	GO:0030864	cortical actin cytoskeleton
0.40	GO:0005628	prospore membrane
0.40	GO:0070938	contractile ring
0.40	GO:0032432	actin filament bundle
0.40	GO:0120025	plasma membrane bounded cell projection
0.40	GO:0000812	Swr1 complex
0.40	GO:0005884	actin filament
0.40	GO:0061645	endocytic patch
0.40	GO:0032155	cell division site part
0.39	GO:0030427	site of polarized growth

0.39	EC:2.3.1.48	GO:0004402
0.36	KEGG:R03457	GO:0004424

sp|P0CG39|POTEJ_HUMAN
POTE ankyrin domain family member J
Search

0.10	POTE ankyrin domain family member J

0.38	GO:0002576	platelet degranulation
0.37	GO:0000916	actomyosin contractile ring contraction
0.37	GO:0000011	vacuole inheritance
0.37	GO:1903475	mitotic actomyosin contractile ring assembly
0.37	GO:0071963	establishment or maintenance of cell polarity regulating cell shape
0.37	GO:0030476	ascospore wall assembly
0.37	GO:0060303	regulation of nucleosome density
0.37	GO:0001300	chronological cell aging
0.37	GO:0043486	histone exchange
0.37	GO:0030010	establishment of cell polarity

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004402	histone acetyltransferase activity
0.36	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0042802	identical protein binding

0.40	GO:0005856	cytoskeleton
0.38	GO:0097433	dense body
0.37	GO:0005628	prospore membrane
0.37	GO:0070938	contractile ring
0.37	GO:0070062	extracellular exosome
0.37	GO:0005925	focal adhesion
0.37	GO:0000812	Swr1 complex
0.37	GO:0043332	mating projection tip
0.37	GO:0061645	endocytic patch
0.37	GO:0032155	cell division site part

0.36

EC:2.3.1.48

GO:0004402

sp|P0CG40|SP9_HUMAN
Transcription factor Sp9
Search

0.96	Sp8 transcription factor b

0.57	GO:0030326	embryonic limb morphogenesis
0.48	GO:0035118	embryonic pectoral fin morphogenesis
0.48	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0009954	proximal/distal pattern formation
0.39	GO:0009953	dorsal/ventral pattern formation
0.37	GO:0007480	imaginal disc-derived leg morphogenesis
0.37	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.47	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0046872	metal ion binding

0.43

GO:0005634

nucleus

sp|P0CG41|CTGE8_HUMAN
cTAGE family member 8
Search

0.83	Cutaneous T-cell lymphoma-associated antigen 1

0.30

GO:0044425

membrane part

sp|P0CG42|F157B_HUMAN
Putative protein FAM157B
Search

sp|P0CG43|F157C_HUMAN
Putative protein FAM157C
Search

sp|P0CG47|UBB_HUMAN
Polyubiquitin-B
Search

UBB

0.57	Polyubiquitin-B

0.59	GO:0021888	hypothalamus gonadotrophin-releasing hormone neuron development
0.58	GO:0060613	fat pad development
0.58	GO:0007144	female meiosis I
0.57	GO:0072520	seminiferous tubule development
0.57	GO:0097009	energy homeostasis
0.57	GO:0007141	male meiosis I
0.55	GO:0008585	female gonad development
0.51	GO:1902527	positive regulation of protein monoubiquitination
0.51	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.50	GO:0047497	mitochondrion transport along microtubule

0.46	GO:0004252	serine-type endopeptidase activity
0.45	GO:0004197	cysteine-type endopeptidase activity
0.44	GO:0070008	serine-type exopeptidase activity
0.43	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.42	GO:0003735	structural constituent of ribosome
0.40	GO:0008026	ATP-dependent helicase activity
0.39	GO:0005515	protein binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0043209	myelin sheath
0.48	GO:0043229	intracellular organelle
0.47	GO:0043025	neuronal cell body
0.47	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0043005	neuron projection
0.46	GO:0044444	cytoplasmic part
0.46	GO:0043228	non-membrane-bounded organelle
0.45	GO:0043227	membrane-bounded organelle
0.38	GO:0019012	virion
0.30	GO:0005615	extracellular space

0.46

GO:0004252

sp|P0CG48|UBC_HUMAN
Polyubiquitin-C
Search

UBC

0.49	Polyubiquitin-C

0.50	GO:1901796	regulation of signal transduction by p53 class mediator
0.50	GO:0035635	entry of bacterium into host cell
0.49	GO:0019985	translesion synthesis
0.49	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.49	GO:0035666	TRIF-dependent toll-like receptor signaling pathway
0.49	GO:0006294	nucleotide-excision repair, preincision complex assembly
0.49	GO:0038128	ERBB2 signaling pathway
0.48	GO:1904380	endoplasmic reticulum mannose trimming
0.48	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.48	GO:0000717	nucleotide-excision repair, DNA duplex unwinding

0.46	GO:0002020	protease binding
0.42	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding

0.50	GO:0005634	nucleus
0.48	GO:0070062	extracellular exosome
0.48	GO:0043209	myelin sheath
0.48	GO:0044322	endoplasmic reticulum quality control compartment
0.46	GO:0030666	endocytic vesicle membrane
0.45	GO:0005840	ribosome
0.44	GO:0010008	endosome membrane
0.44	GO:0005741	mitochondrial outer membrane
0.43	GO:0070013	intracellular organelle lumen
0.42	GO:0005789	endoplasmic reticulum membrane

sp|P0CH98|F106C_HUMAN
Putative protein FAM106C
Search

sp|P0CH99|Z705D_HUMAN
Zinc finger protein 705D
Search

0.84	Zinc finger protein 567

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:0045925	positive regulation of female receptivity
0.37	GO:0016319	mushroom body development
0.36	GO:0008344	adult locomotory behavior
0.36	GO:0031175	neuron projection development
0.33	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0006869	lipid transport

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005319	lipid transporter activity

0.42	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P0CI00|Z705B_HUMAN
Putative zinc finger protein 705B
Search

0.84	Zinc finger protein 567

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:0045925	positive regulation of female receptivity
0.37	GO:0016319	mushroom body development
0.36	GO:0008344	adult locomotory behavior
0.36	GO:0031175	neuron projection development
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:1902680	positive regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005319	lipid transporter activity

0.42	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P0CI01|SPDE6_HUMAN
Putative speedy protein E6
Search

0.12	Speedy protein E4

0.68	GO:0045859	regulation of protein kinase activity
0.67	GO:0008315	G2/MI transition of meiotic cell cycle
0.62	GO:0001556	oocyte maturation
0.61	GO:0051446	positive regulation of meiotic cell cycle
0.57	GO:0006378	mRNA polyadenylation
0.57	GO:0043410	positive regulation of MAPK cascade
0.56	GO:0033674	positive regulation of kinase activity
0.52	GO:0007275	multicellular organism development

0.73	GO:0019901	protein kinase binding
0.58	GO:0030332	cyclin binding

0.50	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0CI25|TRI49_HUMAN
Tripartite motif-containing protein 49
Search

0.96	Tripartite motif-containing protein 49

0.32

GO:0007186

G-protein coupled receptor signaling pathway

0.62	GO:0008270	zinc ion binding
0.36	GO:0019901	protein kinase binding
0.32	GO:0004930	G-protein coupled receptor activity

0.44	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|P0CI26|TR49C_HUMAN
Tripartite motif-containing protein 49C
Search

0.96	Tripartite motif-containing protein 49

0.32

GO:0007186

G-protein coupled receptor signaling pathway

0.62	GO:0008270	zinc ion binding
0.36	GO:0019901	protein kinase binding
0.32	GO:0004930	G-protein coupled receptor activity

0.44	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|P0CJ68|HMN1_HUMAN
Humanin-like 1
Search

sp|P0CJ69|HMN2_HUMAN
Humanin-like 2
Search

sp|P0CJ70|HMN3_HUMAN
Humanin-like 3
Search

sp|P0CJ71|HMN4_HUMAN
Humanin-like 4
Search

sp|P0CJ72|HMN5_HUMAN
Humanin-like 5
Search

sp|P0CJ73|HMN6_HUMAN
Humanin-like 6
Search

sp|P0CJ74|HMN7_HUMAN
Humanin-like 7
Search

sp|P0CJ75|HMN8_HUMAN
Humanin-like 8
Search

sp|P0CJ76|HMN9_HUMAN
Humanin-like 9
Search

sp|P0CJ77|HMN10_HUMAN
Humanin-like 10
Search

sp|P0CJ78|ZN865_HUMAN
Zinc finger protein 865
Search

0.57	Zinc finger protein 865

0.47	GO:0035914	skeletal muscle cell differentiation
0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.38	GO:0097659	nucleic acid-templated transcription
0.37	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.44	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity

0.39	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle

sp|P0CJ79|ZN888_HUMAN
Zinc finger protein 888
Search

0.82	Zinc finger protein 83

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.34	GO:0035556	intracellular signal transduction

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.32	GO:0043233	organelle lumen
0.32	GO:0043228	non-membrane-bounded organelle

sp|P0CJ85|DU4L2_HUMAN
Double homeobox protein 4-like protein 2
Search

0.97	Double homeobox protein 4

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:0070317	negative regulation of G0 to G1 transition
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0008285	negative regulation of cell proliferation
0.39	GO:0006915	apoptotic process
0.37	GO:0008283	cell proliferation
0.34	GO:0045580	regulation of T cell differentiation

0.55	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.32	GO:0016853	isomerase activity

0.61	GO:0005634	nucleus
0.40	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.36	GO:0031975	envelope
0.33	GO:0005667	transcription factor complex

0.32

GO:0016853

sp|P0CJ86|DU4L3_HUMAN
Double homeobox protein 4-like protein 3
Search

0.97	Double homeobox protein 4

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:0070317	negative regulation of G0 to G1 transition
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0008285	negative regulation of cell proliferation
0.39	GO:0006915	apoptotic process
0.37	GO:0008283	cell proliferation
0.34	GO:0045580	regulation of T cell differentiation

0.55	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.32	GO:0016853	isomerase activity

0.61	GO:0005634	nucleus
0.40	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.36	GO:0031975	envelope
0.33	GO:0005667	transcription factor complex

0.32

GO:0016853

sp|P0CJ87|DU4L4_HUMAN
Double homeobox protein 4-like protein 4
Search

0.97	Double homeobox protein 4

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:0070317	negative regulation of G0 to G1 transition
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0008285	negative regulation of cell proliferation
0.39	GO:0006915	apoptotic process
0.37	GO:0008283	cell proliferation
0.34	GO:0045580	regulation of T cell differentiation

0.55	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.32	GO:0016853	isomerase activity

0.61	GO:0005634	nucleus
0.40	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.36	GO:0031975	envelope
0.33	GO:0005667	transcription factor complex

0.32

GO:0016853

sp|P0CJ88|DU4L5_HUMAN
Double homeobox protein 4-like protein 5
Search

0.97	Double homeobox protein 4

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:0070317	negative regulation of G0 to G1 transition
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0008285	negative regulation of cell proliferation
0.39	GO:0006915	apoptotic process
0.37	GO:0008283	cell proliferation
0.34	GO:0045580	regulation of T cell differentiation

0.55	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.32	GO:0016853	isomerase activity

0.61	GO:0005634	nucleus
0.40	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.36	GO:0031975	envelope
0.33	GO:0005667	transcription factor complex

0.32

GO:0016853

sp|P0CJ89|DU4L6_HUMAN
Double homeobox protein 4-like protein 6
Search

0.97	Double homeobox protein 4

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:0070317	negative regulation of G0 to G1 transition
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0008285	negative regulation of cell proliferation
0.39	GO:0006915	apoptotic process
0.37	GO:0008283	cell proliferation
0.34	GO:0045580	regulation of T cell differentiation

0.55	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.32	GO:0016853	isomerase activity

0.61	GO:0005634	nucleus
0.40	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.36	GO:0031975	envelope
0.33	GO:0005667	transcription factor complex

0.32

GO:0016853

sp|P0CJ90|DU4L7_HUMAN
Double homeobox protein 4-like protein 7
Search

0.97	Double homeobox protein 4

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:0070317	negative regulation of G0 to G1 transition
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0008285	negative regulation of cell proliferation
0.39	GO:0006915	apoptotic process
0.37	GO:0008283	cell proliferation
0.34	GO:0045580	regulation of T cell differentiation

0.55	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.32	GO:0016853	isomerase activity

0.61	GO:0005634	nucleus
0.40	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.36	GO:0031975	envelope
0.33	GO:0005667	transcription factor complex

0.32

GO:0016853

sp|P0CJ92|GOG8H_HUMAN
Golgin subfamily A member 8H
Search

sp|P0CK96|S352B_HUMAN
Solute carrier family 35 member E2B
Search

SLC35E2B

0.97	Solute carrier family 35, member E2 (Predicted)

0.36	GO:0006468	protein phosphorylation
0.33	GO:0051301	cell division
0.33	GO:0043547	positive regulation of GTPase activity

0.36	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005096	GTPase activator activity
0.32	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

sp|P0CK97|S35E2_HUMAN
Solute carrier family 35 member E2
Search

0.71	Solute carrier family 35 member E2

0.36	GO:0006468	protein phosphorylation
0.33	GO:0051301	cell division
0.33	GO:0043547	positive regulation of GTPase activity

0.36	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005096	GTPase activator activity
0.32	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

sp|P0CL80|GG12F_HUMAN
G antigen 12F
Search

sp|P0CL81|GG12G_HUMAN
G antigen 12G
Search

sp|P0CL82|GG12I_HUMAN
G antigen 12I
Search

sp|P0CL83|ST3L1_HUMAN
Putative STAG3-like protein 1
Search

STAG3

0.60	Stromal antigen 3

0.78	GO:0007129	synapsis
0.69	GO:0034502	protein localization to chromosome
0.58	GO:0070193	synaptonemal complex organization
0.58	GO:0016322	neuron remodeling
0.48	GO:0022607	cellular component assembly
0.42	GO:0007062	sister chromatid cohesion
0.39	GO:0000070	mitotic sister chromatid segregation
0.39	GO:0045144	meiotic sister chromatid segregation
0.39	GO:0007143	female meiotic nuclear division
0.39	GO:0007140	male meiotic nuclear division

0.53	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding
0.35	GO:0008168	methyltransferase activity
0.33	GO:0003676	nucleic acid binding

0.78	GO:0008278	cohesin complex
0.76	GO:0000802	transverse filament
0.73	GO:0000800	lateral element
0.73	GO:0001673	male germ cell nucleus
0.57	GO:0035327	transcriptionally active chromatin
0.56	GO:0005721	pericentric heterochromatin
0.54	GO:0000780	condensed nuclear chromosome, centromeric region
0.54	GO:0000922	spindle pole
0.40	GO:0005615	extracellular space
0.36	GO:0005654	nucleoplasm

0.35

GO:0008168

sp|P0CL84|ST3L2_HUMAN
Putative STAG3-like protein 2
Search

0.10	Cohesin subunit SA-3 (Fragment)

0.79	GO:0007129	synapsis
0.71	GO:0034502	protein localization to chromosome
0.59	GO:0070193	synaptonemal complex organization
0.58	GO:0016322	neuron remodeling
0.48	GO:0022607	cellular component assembly
0.42	GO:0007062	sister chromatid cohesion
0.39	GO:0000070	mitotic sister chromatid segregation
0.39	GO:0045144	meiotic sister chromatid segregation
0.39	GO:0007143	female meiotic nuclear division
0.39	GO:0007140	male meiotic nuclear division

0.53	GO:0003682	chromatin binding
0.36	GO:0008168	methyltransferase activity
0.35	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.79	GO:0008278	cohesin complex
0.77	GO:0000802	transverse filament
0.74	GO:0000800	lateral element
0.74	GO:0001673	male germ cell nucleus
0.57	GO:0035327	transcriptionally active chromatin
0.56	GO:0005721	pericentric heterochromatin
0.54	GO:0000780	condensed nuclear chromosome, centromeric region
0.54	GO:0000922	spindle pole
0.40	GO:0005615	extracellular space
0.37	GO:0005654	nucleoplasm

0.36

GO:0008168

sp|P0CL85|ST3L3_HUMAN
STAG3-like protein 3
Search

0.10	Cohesin subunit SA-3 (Fragment)

0.79	GO:0007129	synapsis
0.71	GO:0034502	protein localization to chromosome
0.58	GO:0070193	synaptonemal complex organization
0.58	GO:0016322	neuron remodeling
0.48	GO:0022607	cellular component assembly
0.42	GO:0007062	sister chromatid cohesion
0.39	GO:0000070	mitotic sister chromatid segregation
0.39	GO:0045144	meiotic sister chromatid segregation
0.39	GO:0007143	female meiotic nuclear division
0.39	GO:0007140	male meiotic nuclear division

0.52	GO:0003682	chromatin binding
0.36	GO:0008168	methyltransferase activity
0.35	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.79	GO:0008278	cohesin complex
0.77	GO:0000802	transverse filament
0.74	GO:0000800	lateral element
0.74	GO:0001673	male germ cell nucleus
0.57	GO:0035327	transcriptionally active chromatin
0.56	GO:0005721	pericentric heterochromatin
0.54	GO:0000780	condensed nuclear chromosome, centromeric region
0.54	GO:0000922	spindle pole
0.40	GO:0005615	extracellular space
0.37	GO:0005654	nucleoplasm

0.36

GO:0008168

sp|P0CV98|TSPY3_HUMAN
Testis-specific Y-encoded protein 3
Search

0.91	Testis-specific Y-encoded protein 3

0.79	GO:0006334	nucleosome assembly
0.46	GO:0007506	gonadal mesoderm development
0.43	GO:0007283	spermatogenesis
0.41	GO:0030154	cell differentiation
0.37	GO:0071480	cellular response to gamma radiation
0.37	GO:0051897	positive regulation of protein kinase B signaling
0.37	GO:0031398	positive regulation of protein ubiquitination
0.36	GO:0008284	positive regulation of cell proliferation
0.36	GO:0008283	cell proliferation
0.33	GO:0040008	regulation of growth

0.34

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|P0CV99|TSPY4_HUMAN
Testis-specific Y-encoded protein 4
Search

0.70

TSPY

0.79	GO:0006334	nucleosome assembly
0.42	GO:0071480	cellular response to gamma radiation
0.41	GO:0051897	positive regulation of protein kinase B signaling
0.40	GO:0031398	positive regulation of protein ubiquitination
0.40	GO:0008284	positive regulation of cell proliferation

0.61

GO:0005634

nucleus

sp|P0CW00|TSPY8_HUMAN
Testis-specific Y-encoded protein 8
Search

0.91	Testis-specific Y-encoded protein 8

0.79	GO:0006334	nucleosome assembly
0.46	GO:0007506	gonadal mesoderm development
0.43	GO:0007283	spermatogenesis
0.41	GO:0030154	cell differentiation
0.37	GO:0071480	cellular response to gamma radiation
0.37	GO:0051897	positive regulation of protein kinase B signaling
0.37	GO:0031398	positive regulation of protein ubiquitination
0.36	GO:0008284	positive regulation of cell proliferation
0.36	GO:0008283	cell proliferation
0.33	GO:0040008	regulation of growth

0.34

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|P0CW01|TSPYA_HUMAN
Testis-specific Y-encoded protein 10
Search

0.70

TSPY

0.79	GO:0006334	nucleosome assembly
0.42	GO:0071480	cellular response to gamma radiation
0.41	GO:0051897	positive regulation of protein kinase B signaling
0.40	GO:0031398	positive regulation of protein ubiquitination
0.40	GO:0008284	positive regulation of cell proliferation

0.61

GO:0005634

nucleus

sp|P0CW18|PRS56_HUMAN
Serine protease 56
Search

PRSS56

0.97	Serine protease 56

0.61	GO:0006508	proteolysis
0.52	GO:0043010	camera-type eye development
0.46	GO:0007596	blood coagulation
0.42	GO:0060672	epithelial cell morphogenesis involved in placental branching
0.40	GO:0030216	keratinocyte differentiation
0.40	GO:0001843	neural tube closure
0.38	GO:1904627	response to phorbol 13-acetate 12-myristate
0.38	GO:0007341	penetration of zona pellucida
0.38	GO:0007190	activation of adenylate cyclase activity
0.37	GO:0007340	acrosome reaction

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0005509	calcium ion binding
0.37	GO:0005537	mannose binding
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0022848	acetylcholine-gated cation-selective channel activity
0.34	GO:0099600	transmembrane receptor activity
0.33	GO:0042806	fucose binding
0.33	GO:0002020	protease binding
0.33	GO:0001855	complement component C4b binding
0.33	GO:0004040	amidase activity

0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005576	extracellular region
0.40	GO:0001669	acrosomal vesicle
0.39	GO:0019897	extrinsic component of plasma membrane
0.36	GO:0098590	plasma membrane region
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0098794	postsynapse
0.35	GO:0031984	organelle subcompartment
0.35	GO:0030054	cell junction
0.34	GO:0043234	protein complex

0.69

GO:0004252

sp|P0CW19|LIMS3_HUMAN
LIM and senescent cell antigen-like-containing domain protein 3
Search

0.88	LIM zinc finger domain containing 1

0.61	GO:0045216	cell-cell junction organization
0.52	GO:0051894	positive regulation of focal adhesion assembly
0.51	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.51	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.51	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.49	GO:0071560	cellular response to transforming growth factor beta stimulus
0.47	GO:0043547	positive regulation of GTPase activity
0.46	GO:0010628	positive regulation of gene expression
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0045184	establishment of protein localization

0.53	GO:0046872	metal ion binding
0.48	GO:0019901	protein kinase binding
0.34	GO:0019904	protein domain specific binding

0.62	GO:0005925	focal adhesion
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005911	cell-cell junction
0.45	GO:0005886	plasma membrane
0.37	GO:0030018	Z disc
0.34	GO:0043234	protein complex
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P0CW20|LIMS4_HUMAN
LIM and senescent cell antigen-like-containing domain protein 4
Search

0.88	LIM zinc finger domain containing 1

0.61	GO:0045216	cell-cell junction organization
0.52	GO:0051894	positive regulation of focal adhesion assembly
0.51	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.51	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.51	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.49	GO:0071560	cellular response to transforming growth factor beta stimulus
0.47	GO:0043547	positive regulation of GTPase activity
0.46	GO:0010628	positive regulation of gene expression
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0045184	establishment of protein localization

0.53	GO:0046872	metal ion binding
0.48	GO:0019901	protein kinase binding
0.34	GO:0019904	protein domain specific binding

0.62	GO:0005925	focal adhesion
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005911	cell-cell junction
0.45	GO:0005886	plasma membrane
0.37	GO:0030018	Z disc
0.34	GO:0043234	protein complex
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P0CW21|SPGOS_HUMAN
Putative uncharacterized protein SPG20-AS1
Search

sp|P0CW23|AKAI1_HUMAN
A-kinase anchor protein inhibitor 1
Search

AKAIN1

0.97	A-kinase anchor protein inhibitor 1

0.76	GO:0031333	negative regulation of protein complex assembly
0.72	GO:0010738	regulation of protein kinase A signaling
0.56	GO:0008104	protein localization

0.85

GO:0051018

protein kinase A binding

0.69

GO:0005829

cytosol

sp|P0CW24|PNM6A_HUMAN
Paraneoplastic antigen-like protein 6A
Search

PNMA3

0.97	Paraneoplastic Ma antigen 3

0.43

GO:0043065

positive regulation of apoptotic process

0.61	GO:0008270	zinc ion binding
0.49	GO:0003676	nucleic acid binding
0.43	GO:0005515	protein binding

0.45

GO:0005730

nucleolus

sp|P0CW27|CC166_HUMAN
Coiled-coil domain-containing protein 166
Search

CCDC166

0.39	Nicotinate phosphoribosyltransferase

0.42	GO:0019358	nicotinate nucleotide salvage
0.40	GO:0009435	NAD biosynthetic process
0.40	GO:0006979	response to oxidative stress

0.42	GO:0004516	nicotinate phosphoribosyltransferase activity
0.42	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity

0.39

GO:0005829

cytosol

0.42	EC:2.4.2.11	GO:0004516
0.42	KEGG:R01724	GO:0004516

sp|P0CW71|MCP1_HUMAN
Putative metaphase chromosome protein 1
Search

sp|P0CZ25|D10OS_HUMAN
Uncharacterized protein DNAH10OS
Search

sp|P0DH78|RN224_HUMAN
RING finger protein 224
Search

RNF224

0.97	RING finger protein 224

0.38	GO:0044341	sodium-dependent phosphate transport
0.37	GO:0001778	plasma membrane repair
0.37	GO:0046627	negative regulation of insulin receptor signaling pathway
0.35	GO:0016567	protein ubiquitination
0.34	GO:0097503	sialylation
0.33	GO:0006486	protein glycosylation

0.54	GO:0046872	metal ion binding
0.38	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.35	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0008373	sialyltransferase activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0031526	brush border membrane
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.34

EC:2.4.99

GO:0008373

sp|P0DI80|SMIM6_HUMAN
Small integral membrane protein 6
Search

SMIM6

0.97	Small integral membrane protein 6

0.30

GO:0044425

membrane part

sp|P0DI81|TPC2A_HUMAN
Trafficking protein particle complex subunit 2
Search

TRAPPC2

0.88	Trafficking protein particle complex subunit 2

0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.41	GO:0001501	skeletal system development
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0006901	vesicle coating
0.35	GO:0048199	vesicle targeting, to, from or within Golgi
0.34	GO:0048194	Golgi vesicle budding
0.33	GO:0006461	protein complex assembly

0.42	GO:0044325	ion channel binding
0.39	GO:0008134	transcription factor binding
0.35	GO:0017112	Rab guanyl-nucleotide exchange factor activity

0.49	GO:0005737	cytoplasm
0.42	GO:0030008	TRAPP complex
0.40	GO:0005634	nucleus
0.39	GO:0012505	endomembrane system
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.34	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

sp|P0DI82|TPC2B_HUMAN
Trafficking protein particle complex subunit 2B
Search

TRAPPC2

0.88	Trafficking protein particle complex subunit 2

0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.41	GO:0001501	skeletal system development
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0006901	vesicle coating
0.35	GO:0048199	vesicle targeting, to, from or within Golgi
0.34	GO:0048194	Golgi vesicle budding
0.33	GO:0006461	protein complex assembly

0.42	GO:0044325	ion channel binding
0.39	GO:0008134	transcription factor binding
0.35	GO:0017112	Rab guanyl-nucleotide exchange factor activity

0.49	GO:0005737	cytoplasm
0.42	GO:0030008	TRAPP complex
0.40	GO:0005634	nucleus
0.39	GO:0012505	endomembrane system
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.34	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

sp|P0DJ07|PT100_HUMAN
Protein PET100 homolog, mitochondrial
Search

0.47	Putative mitochondrial protein (Fragment)

0.84

GO:0033617

mitochondrial respiratory chain complex IV assembly

0.48

GO:0051082

unfolded protein binding

0.61	GO:0005739	mitochondrion
0.50	GO:0031301	integral component of organelle membrane
0.44	GO:0019866	organelle inner membrane

sp|P0DJ93|SIM13_HUMAN
Small integral membrane protein 13
Search

SMIM13

0.97	Small integral membrane protein 13

0.30

GO:0044425

membrane part

sp|P0DJD0|RGPD1_HUMAN
RANBP2-like and GRIP domain-containing protein 1
Search

0.91	RanBP2-like and GRIP domain-containing protein 3

0.69	GO:0046907	intracellular transport
0.50	GO:0000413	protein peptidyl-prolyl isomerization
0.48	GO:0046604	positive regulation of mitotic centrosome separation
0.45	GO:0000082	G1/S transition of mitotic cell cycle
0.45	GO:0006606	protein import into nucleus
0.45	GO:0007051	spindle organization
0.43	GO:0043547	positive regulation of GTPase activity
0.43	GO:0006405	RNA export from nucleus
0.42	GO:0006511	ubiquitin-dependent protein catabolic process
0.33	GO:0006457	protein folding

0.50	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.50	GO:0008536	Ran GTPase binding
0.43	GO:0005096	GTPase activator activity
0.42	GO:0046872	metal ion binding

0.45	GO:0005622	intracellular
0.41	GO:0044422	organelle part
0.41	GO:0012505	endomembrane system
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0031975	envelope
0.39	GO:0043234	protein complex
0.38	GO:0043228	non-membrane-bounded organelle

0.50

GO:0003755

sp|P0DJD1|RGPD2_HUMAN
RANBP2-like and GRIP domain-containing protein 2
Search

0.94	RanBP2-like and GRIP domain-containing protein 3

0.69	GO:0046907	intracellular transport
0.50	GO:0000413	protein peptidyl-prolyl isomerization
0.48	GO:0046604	positive regulation of mitotic centrosome separation
0.45	GO:0000082	G1/S transition of mitotic cell cycle
0.45	GO:0006606	protein import into nucleus
0.45	GO:0007051	spindle organization
0.43	GO:0043547	positive regulation of GTPase activity
0.43	GO:0006405	RNA export from nucleus
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.33	GO:0006457	protein folding

0.50	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.50	GO:0008536	Ran GTPase binding
0.43	GO:0005096	GTPase activator activity
0.42	GO:0046872	metal ion binding

0.45	GO:0005622	intracellular
0.41	GO:0044422	organelle part
0.41	GO:0012505	endomembrane system
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0031975	envelope
0.39	GO:0043234	protein complex
0.38	GO:0043228	non-membrane-bounded organelle

0.50

GO:0003755

sp|P0DJD3|RBY1A_HUMAN
RNA-binding motif protein, Y chromosome, family 1 member A1
Search

0.60	RNA binding motif protein, X-linked

0.49	GO:0006509	membrane protein ectodomain proteolysis
0.49	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.49	GO:0071347	cellular response to interleukin-1
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0008380	RNA splicing
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0051259	protein oligomerization
0.44	GO:0006397	mRNA processing
0.43	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.43	GO:0048026	positive regulation of mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.48	GO:0001047	core promoter binding
0.46	GO:0003682	chromatin binding
0.43	GO:0042802	identical protein binding
0.43	GO:0019904	protein domain specific binding

0.51	GO:0044530	supraspliceosomal complex
0.49	GO:0005719	nuclear euchromatin
0.47	GO:0071013	catalytic step 2 spliceosome
0.47	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P0DJD4|RBY1C_HUMAN
RNA-binding motif protein, Y chromosome, family 1 member C
Search

0.60	RNA binding motif protein, X-linked

0.49	GO:0006509	membrane protein ectodomain proteolysis
0.49	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.49	GO:0071347	cellular response to interleukin-1
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0008380	RNA splicing
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0051259	protein oligomerization
0.44	GO:0006397	mRNA processing
0.43	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.43	GO:0048026	positive regulation of mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.48	GO:0001047	core promoter binding
0.46	GO:0003682	chromatin binding
0.43	GO:0042802	identical protein binding
0.43	GO:0019904	protein domain specific binding

0.51	GO:0044530	supraspliceosomal complex
0.49	GO:0005719	nuclear euchromatin
0.47	GO:0071013	catalytic step 2 spliceosome
0.47	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P0DJD7|PEPA4_HUMAN
Pepsin A-4
Search

0.91	Pepsinogen III

0.61	GO:0006508	proteolysis
0.50	GO:0007586	digestion
0.49	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.45	GO:0051604	protein maturation
0.42	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.39	GO:0042803	protein homodimerization activity

0.43	GO:0005576	extracellular region
0.42	GO:0005768	endosome
0.37	GO:0044433	cytoplasmic vesicle part
0.36	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|P0DJD8|PEPA3_HUMAN
Pepsin A-3
Search

0.91	Pepsinogen III

0.61	GO:0006508	proteolysis
0.50	GO:0007586	digestion
0.49	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.45	GO:0051604	protein maturation
0.42	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.39	GO:0042803	protein homodimerization activity

0.43	GO:0005576	extracellular region
0.42	GO:0005768	endosome
0.37	GO:0044433	cytoplasmic vesicle part
0.36	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|P0DJD9|PEPA5_HUMAN
Pepsin A-5
Search

0.91	Pepsinogen III

0.61	GO:0006508	proteolysis
0.50	GO:0007586	digestion
0.48	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.45	GO:0051604	protein maturation
0.41	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.38	GO:0042803	protein homodimerization activity

0.43	GO:0005576	extracellular region
0.41	GO:0005768	endosome
0.37	GO:0044433	cytoplasmic vesicle part
0.36	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|P0DJG4|THEGL_HUMAN
Testicular haploid expressed gene protein-like
Search

THEGL

0.96	Theg spermatid protein like

sp|P0DJH9|RD3L_HUMAN
Protein RD3-like
Search

RD3L

0.97	Retinal degeneration 3-like

sp|P0DJI8|SAA1_HUMAN
Serum amyloid A-1 protein
Search

0.94	Serum amyloid A protein (Fragment)

0.85	GO:0006953	acute-phase response
0.55	GO:0050918	positive chemotaxis
0.53	GO:0060326	cell chemotaxis
0.42	GO:0010739	positive regulation of protein kinase A signaling
0.41	GO:0043410	positive regulation of MAPK cascade
0.41	GO:0050996	positive regulation of lipid catabolic process
0.41	GO:0035634	response to stilbenoid
0.41	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.40	GO:0070372	regulation of ERK1 and ERK2 cascade
0.39	GO:0007252	I-kappaB phosphorylation

0.56	GO:0042056	chemoattractant activity
0.40	GO:0035662	Toll-like receptor 4 binding
0.39	GO:0008201	heparin binding
0.38	GO:0001664	G-protein coupled receptor binding
0.34	GO:0042802	identical protein binding

0.85	GO:0034364	high-density lipoprotein particle
0.39	GO:0005881	cytoplasmic microtubule
0.36	GO:0070062	extracellular exosome
0.36	GO:0071682	endocytic vesicle lumen
0.30	GO:0016020	membrane

sp|P0DJI9|SAA2_HUMAN
Serum amyloid A-2 protein
Search

0.94	Serum amyloid A protein (Fragment)

0.85	GO:0006953	acute-phase response
0.55	GO:0050918	positive chemotaxis
0.53	GO:0060326	cell chemotaxis
0.42	GO:0010739	positive regulation of protein kinase A signaling
0.41	GO:0043410	positive regulation of MAPK cascade
0.41	GO:0050996	positive regulation of lipid catabolic process
0.41	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.40	GO:0070372	regulation of ERK1 and ERK2 cascade
0.40	GO:0035634	response to stilbenoid
0.39	GO:0007252	I-kappaB phosphorylation

0.56	GO:0042056	chemoattractant activity
0.40	GO:0035662	Toll-like receptor 4 binding
0.38	GO:0008201	heparin binding
0.36	GO:0001664	G-protein coupled receptor binding
0.34	GO:0042802	identical protein binding

0.85	GO:0034364	high-density lipoprotein particle
0.37	GO:0005881	cytoplasmic microtubule
0.36	GO:0070062	extracellular exosome
0.36	GO:0071682	endocytic vesicle lumen
0.30	GO:0016020	membrane

sp|P0DJJ0|SRG2C_HUMAN
SLIT-ROBO Rho GTPase-activating protein 2C
Search

0.67	SLIT-ROBO Rho GTPase activating protein 2

0.73	GO:0043547	positive regulation of GTPase activity
0.59	GO:0007165	signal transduction
0.54	GO:0021816	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
0.52	GO:0046847	filopodium assembly
0.51	GO:0060996	dendritic spine development
0.48	GO:0048812	neuron projection morphogenesis
0.45	GO:0030336	negative regulation of cell migration
0.42	GO:2001222	regulation of neuron migration
0.41	GO:0003363	lamellipodium assembly involved in ameboidal cell migration
0.40	GO:0051014	actin filament severing

0.74	GO:0005096	GTPase activator activity
0.53	GO:0048365	Rac GTPase binding
0.47	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0045335	phagocytic vesicle
0.49	GO:0014069	postsynaptic density
0.48	GO:0045211	postsynaptic membrane
0.44	GO:0005829	cytosol
0.42	GO:0044327	dendritic spine head
0.41	GO:0019866	organelle inner membrane
0.41	GO:0031966	mitochondrial membrane
0.39	GO:0030027	lamellipodium
0.38	GO:0030054	cell junction
0.36	GO:0005634	nucleus

sp|P0DJR0|GIMD1_HUMAN
GTPase IMAP family member GIMD1
Search

GIMD1

0.95	GIMAP family P-loop NTPase domain containing 1

0.66

GO:0005525

GTP binding

sp|P0DKB5|TPBGL_HUMAN
Trophoblast glycoprotein-like
Search

TPBGL

0.88	Trophoblast glycoprotein like

0.39

GO:0051965

positive regulation of synapse assembly

0.36	GO:0005783	endoplasmic reticulum
0.33	GO:0009986	cell surface
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P0DKB6|MPC1L_HUMAN
Mitochondrial pyruvate carrier 1-like protein
Search

0.60	Mitochondrial pyruvate carrier

0.84	GO:0006850	mitochondrial pyruvate transmembrane transport
0.42	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate
0.40	GO:1990830	cellular response to leukemia inhibitory factor
0.39	GO:0042254	ribosome biogenesis
0.35	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0016192	vesicle-mediated transport
0.33	GO:0015031	protein transport
0.33	GO:0006468	protein phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.49	GO:0050833	pyruvate transmembrane transporter activity
0.35	GO:0004866	endopeptidase inhibitor activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0003676	nucleic acid binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0016491	oxidoreductase activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.43	GO:0031301	integral component of organelle membrane
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0005615	extracellular space
0.33	GO:0019013	viral nucleocapsid

0.32

GO:0016491

sp|P0DKL9|A14EL_HUMAN
ARL14 effector protein-like
Search

ARL14EPL

0.97	ADP ribosylation factor-like GTPase 14 effector protein like

0.45

GO:0006508

proteolysis

0.50	GO:0004177	aminopeptidase activity
0.48	GO:0008237	metallopeptidase activity
0.48	GO:0003677	DNA binding
0.46	GO:0008270	zinc ion binding
0.37	GO:0046983	protein dimerization activity

0.45	GO:0005925	focal adhesion
0.43	GO:0005730	nucleolus
0.42	GO:0005829	cytosol
0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.50

EC:3.4.11

GO:0004177

sp|P0DKV0|S31C1_HUMAN
Spermatogenesis-associated protein 31C1
Search

0.45	Spermatogenesis-associated protein 31C1

0.80	GO:0007283	spermatogenesis
0.72	GO:0030154	cell differentiation

0.30

GO:0031224

intrinsic component of membrane

sp|P0DKX0|ZN728_HUMAN
Zinc finger protein 728
Search

0.64	Zinc finger protein 85

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.41	GO:0097659	nucleic acid-templated transcription
0.40	GO:0010467	gene expression
0.39	GO:0034645	cellular macromolecule biosynthetic process

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.46	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0044446	intracellular organelle part

sp|P0DKX4|SIM18_HUMAN
Small integral membrane protein 18
Search

SMIM18

0.97	Small integral membrane protein 18

0.30

GO:0044425

membrane part

sp|P0DL12|SIM17_HUMAN
Small integral membrane protein 17
Search

SMIM17

0.97	Small integral membrane protein 17

0.30

GO:0044425

membrane part

sp|P0DM35|M1BL1_HUMAN
Metallothionein 1H-like protein 1
Search

0.76	Metallothionein-I, hippocampal

0.63	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0071276	cellular response to cadmium ion
0.48	GO:0036018	cellular response to erythropoietin
0.44	GO:0036015	response to interleukin-3
0.42	GO:0035690	cellular response to drug
0.38	GO:0071280	cellular response to copper ion
0.37	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.37	GO:0006875	cellular metal ion homeostasis
0.37	GO:0014002	astrocyte development

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.36	GO:0008144	drug binding
0.35	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.35	GO:0030295	protein kinase activator activity

0.53	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.35	GO:0016234	inclusion body
0.35	GO:0008021	synaptic vesicle
0.34	GO:0005829	cytosol

sp|P0DM63|NPIA8_HUMAN
Nuclear pore complex-interacting protein family member A8
Search

0.82	Nuclear pore complex-interacting protein family member A7

0.35	GO:0051028	mRNA transport
0.34	GO:0015031	protein transport

0.38

GO:0005515

protein binding

0.60	GO:0005654	nucleoplasm
0.36	GO:0031965	nuclear membrane
0.35	GO:0005643	nuclear pore
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P0DMB1|P23D2_HUMAN
Proline-rich protein 23D2
Search

0.44	Proline-rich protein 23D2

sp|P0DMB2|CH088_HUMAN
Uncharacterized protein C8orf88
Search

0.79

Granulito

0.72

GO:0045947

negative regulation of translational initiation

0.77

GO:0008190

eukaryotic initiation factor 4E binding

0.49	GO:0043186	P granule
0.30	GO:0031224	intrinsic component of membrane

sp|P0DMC3|ELA_HUMAN
Apelin receptor early endogenous ligand
Search

APELA

0.97	Apelin receptor early endogenous ligand

0.85	GO:1904022	positive regulation of G-protein coupled receptor internalization
0.84	GO:0060183	apelin receptor signaling pathway
0.81	GO:1901165	positive regulation of trophoblast cell migration
0.81	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.77	GO:0060976	coronary vasculature development
0.76	GO:0060395	SMAD protein signal transduction
0.76	GO:0001570	vasculogenesis
0.75	GO:0035050	embryonic heart tube development
0.72	GO:0090133	mesendoderm migration
0.70	GO:0007509	mesoderm migration involved in gastrulation

0.83	GO:0031704	apelin receptor binding
0.70	GO:0005179	hormone activity

0.65	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P0DME0|SETLP_HUMAN
Protein SETSIP
Search

SET

0.92	SET nuclear proto-oncogene

0.79	GO:0006334	nucleosome assembly
0.42	GO:0048884	neuromast development
0.39	GO:0043524	negative regulation of neuron apoptotic process
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.37	GO:0045446	endothelial cell differentiation
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0006468	protein phosphorylation
0.35	GO:0035067	negative regulation of histone acetylation
0.35	GO:0031498	chromatin disassembly
0.35	GO:0032986	protein-DNA complex disassembly

0.38	GO:0017049	GTP-Rho binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0003682	chromatin binding
0.35	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0042393	histone binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0005811	lipid droplet
0.38	GO:0031974	membrane-enclosed lumen
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004674

sp|P0DML2|CSH1_HUMAN
Chorionic somatomammotropin hormone 1
Search

0.86	Chorionic somatomammotropin hormone B

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0071375	cellular response to peptide hormone stimulus
0.41	GO:0032094	response to food
0.41	GO:0060416	response to growth hormone
0.41	GO:0007259	JAK-STAT cascade
0.41	GO:0040018	positive regulation of multicellular organism growth
0.40	GO:0032868	response to insulin
0.39	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.79	GO:0005179	hormone activity
0.41	GO:0005131	growth hormone receptor binding
0.38	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.44	GO:0031982	vesicle
0.42	GO:0012505	endomembrane system
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0044444	cytoplasmic part
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen
0.35	GO:0005886	plasma membrane

sp|P0DML3|CSH2_HUMAN
Chorionic somatomammotropin hormone 2
Search

0.86	Chorionic somatomammotropin hormone B

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0071375	cellular response to peptide hormone stimulus
0.41	GO:0032094	response to food
0.41	GO:0060416	response to growth hormone
0.41	GO:0007259	JAK-STAT cascade
0.41	GO:0040018	positive regulation of multicellular organism growth
0.40	GO:0032868	response to insulin
0.39	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.79	GO:0005179	hormone activity
0.41	GO:0005131	growth hormone receptor binding
0.38	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.44	GO:0031982	vesicle
0.42	GO:0012505	endomembrane system
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0044444	cytoplasmic part
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen
0.35	GO:0005886	plasma membrane

sp|P0DMM9|ST1A3_HUMAN
Sulfotransferase 1A3
Search

0.57	Sulfotransferase

0.47	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.47	GO:0006068	ethanol catabolic process
0.46	GO:0051923	sulfation
0.45	GO:0018958	phenol-containing compound metabolic process
0.43	GO:0009812	flavonoid metabolic process
0.43	GO:0006805	xenobiotic metabolic process
0.42	GO:0008202	steroid metabolic process
0.40	GO:0042445	hormone metabolic process
0.38	GO:0030855	epithelial cell differentiation
0.36	GO:0006575	cellular modified amino acid metabolic process

0.78	GO:0008146	sulfotransferase activity
0.36	GO:0043199	sulfate binding
0.36	GO:0005515	protein binding
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding

0.38

GO:0005829

cytosol

0.78

EC:2.8.2

GO:0008146

sp|P0DMN0|ST1A4_HUMAN
Sulfotransferase 1A4
Search

0.57	Sulfotransferase

0.47	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.47	GO:0006068	ethanol catabolic process
0.46	GO:0051923	sulfation
0.45	GO:0018958	phenol-containing compound metabolic process
0.43	GO:0009812	flavonoid metabolic process
0.43	GO:0006805	xenobiotic metabolic process
0.42	GO:0008202	steroid metabolic process
0.40	GO:0042445	hormone metabolic process
0.38	GO:0030855	epithelial cell differentiation
0.36	GO:0006575	cellular modified amino acid metabolic process

0.78	GO:0008146	sulfotransferase activity
0.36	GO:0043199	sulfate binding
0.36	GO:0005515	protein binding
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding

0.38

GO:0005829

cytosol

0.78

EC:2.8.2

GO:0008146

sp|P0DMP1|HMN12_HUMAN
Humanin-like 12
Search

sp|P0DMP2|SRG2B_HUMAN
SLIT-ROBO Rho GTPase-activating protein 2B
Search

0.78	SLIT-ROBO Rho GTPase activating protein 2

0.73	GO:0043547	positive regulation of GTPase activity
0.59	GO:0007165	signal transduction
0.53	GO:0021816	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
0.51	GO:0046847	filopodium assembly
0.51	GO:0060996	dendritic spine development
0.47	GO:0048812	neuron projection morphogenesis
0.45	GO:0030336	negative regulation of cell migration
0.41	GO:2001222	regulation of neuron migration
0.41	GO:0003363	lamellipodium assembly involved in ameboidal cell migration
0.40	GO:0051014	actin filament severing

0.74	GO:0005096	GTPase activator activity
0.53	GO:0048365	Rac GTPase binding
0.46	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0045335	phagocytic vesicle
0.49	GO:0014069	postsynaptic density
0.47	GO:0045211	postsynaptic membrane
0.44	GO:0005829	cytosol
0.41	GO:0044327	dendritic spine head
0.41	GO:0019866	organelle inner membrane
0.41	GO:0031966	mitochondrial membrane
0.39	GO:0030027	lamellipodium
0.38	GO:0030054	cell junction
0.36	GO:0005634	nucleus

sp|P0DMQ5|INAM2_HUMAN
Putative transmembrane protein INAFM2
Search

INAFM2

0.97	InaF motif containing 2

0.33	GO:0009405	pathogenesis
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.33	GO:0004872	receptor activity
0.33	GO:0005506	iron ion binding

0.33	GO:0009279	cell outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.13.11

GO:0016702

sp|P0DMQ9|CH089_HUMAN
Putative uncharacterized protein C8orf89
Search

sp|P0DMR1|HNRC4_HUMAN
Heterogeneous nuclear ribonucleoprotein C-like 4
Search

HNRNPC

0.96	Heterogeneous nuclear ribonucleoprotein C

0.44	GO:0070935	3'-UTR-mediated mRNA stabilization
0.44	GO:0032211	negative regulation of telomere maintenance via telomerase
0.43	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:0001649	osteoblast differentiation
0.38	GO:0043044	ATP-dependent chromatin remodeling
0.38	GO:0090367	negative regulation of mRNA modification
0.35	GO:0043086	negative regulation of catalytic activity
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.59	GO:0003723	RNA binding
0.41	GO:0042802	identical protein binding
0.39	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.39	GO:0031492	nucleosomal DNA binding
0.38	GO:1990827	deaminase binding
0.38	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0019904	protein domain specific binding
0.35	GO:0004857	enzyme inhibitor activity
0.35	GO:0043021	ribonucleoprotein complex binding
0.34	GO:0004984	olfactory receptor activity

0.65	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.41	GO:0015629	actin cytoskeleton
0.39	GO:0005829	cytosol
0.39	GO:0044446	intracellular organelle part
0.39	GO:0005576	extracellular region
0.38	GO:1902494	catalytic complex
0.37	GO:0043234	protein complex

sp|P0DMR2|SG1C2_HUMAN
Secretoglobin family 1C member 2
Search

SCGB1C1

0.96	Secretoglobin RYD5

0.43

GO:0007165

signal transduction

0.63

GO:0005576

extracellular region

sp|P0DMR3|AT8OS_HUMAN
Putative protein ATXN8OS
Search

sp|P0DMS8|AA3R_HUMAN
Adenosine receptor A3
Search

ADORA3

0.74	Adenosine receptor A3

0.85	GO:0001973	adenosine receptor signaling pathway
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0030336	negative regulation of cell migration
0.50	GO:0008285	negative regulation of cell proliferation
0.39	GO:0002441	histamine secretion involved in inflammatory response
0.38	GO:0043306	positive regulation of mast cell degranulation
0.38	GO:0070257	positive regulation of mucus secretion
0.38	GO:0043303	mast cell degranulation
0.38	GO:0050850	positive regulation of calcium-mediated signaling
0.38	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.85

GO:0001609

G-protein coupled adenosine receptor activity

0.55	GO:0005886	plasma membrane
0.38	GO:0042629	mast cell granule
0.35	GO:0098793	presynapse
0.30	GO:0016021	integral component of membrane

sp|P0DMS9|TMIG3_HUMAN
Transmembrane domain-containing protein TMIGD3
Search

TMIGD3

0.60	Transmembrane and immunoglobulin domain containing 3

0.61	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.59	GO:0030336	negative regulation of cell migration
0.57	GO:0008285	negative regulation of cell proliferation
0.55	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0007190	activation of adenylate cyclase activity
0.40	GO:0008016	regulation of heart contraction
0.40	GO:0006954	inflammatory response
0.39	GO:0009611	response to wounding
0.35	GO:0032680	regulation of tumor necrosis factor production
0.35	GO:0032675	regulation of interleukin-6 production

0.55	GO:0004930	G-protein coupled receptor activity
0.35	GO:0104005	hijacked molecular function

0.37

GO:0005887

integral component of plasma membrane

sp|P0DMT0|MLN_HUMAN
Myoregulin
Search

sp|P0DMU2|OR83P_HUMAN
Putative olfactory receptor 8G3 pseudogene
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.55	GO:0005549	odorant binding

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0DMU3|F231L_HUMAN
FAM231A/C-like protein LOC102723383
Search

sp|P0DMU4|F231A_HUMAN
Protein FAM231A
Search

sp|P0DMU5|F231C_HUMAN
Protein FAM231C
Search

sp|P0DMU7|CT456_HUMAN
Cancer/testis antigen family 45 member A6
Search

sp|P0DMU8|CT455_HUMAN
Cancer/testis antigen family 45 member A5
Search

sp|P0DMU9|CT45A_HUMAN
Cancer/testis antigen family 45 member A10
Search

sp|P0DMV0|CT457_HUMAN
Cancer/testis antigen family 45 member A7
Search

sp|P0DMV1|CT458_HUMAN
Cancer/testis antigen family 45 member A8
Search

sp|P0DMV2|CT459_HUMAN
Cancer/testis antigen family 45 member A9
Search

sp|P0DMV8|HS71A_HUMAN
Heat shock 70 kDa protein 1A
Search

0.53	Inducible heat shock protein 70

0.52	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0010638	positive regulation of organelle organization
0.52	GO:0042026	protein refolding
0.50	GO:0010821	regulation of mitochondrion organization
0.50	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.50	GO:1903533	regulation of protein targeting
0.50	GO:0090316	positive regulation of intracellular protein transport
0.48	GO:0010968	regulation of microtubule nucleation
0.47	GO:1901673	regulation of mitotic spindle assembly
0.44	GO:0032273	positive regulation of protein polymerization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0031072	heat shock protein binding
0.47	GO:0051082	unfolded protein binding
0.41	GO:0055131	C3HC4-type RING finger domain binding
0.41	GO:0031249	denatured protein binding
0.41	GO:0001106	RNA polymerase II transcription corepressor activity

0.53	GO:0002199	zona pellucida receptor complex
0.49	GO:0044297	cell body
0.49	GO:0008180	COP9 signalosome
0.46	GO:0005829	cytosol
0.44	GO:0005813	centrosome
0.41	GO:0072562	blood microparticle
0.40	GO:0016235	aggresome
0.39	GO:0005814	centriole
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0070062	extracellular exosome

0.34	EC:6.1.1.9	GO:0004832
0.34	KEGG:R03665	GO:0004832

sp|P0DMV9|HS71B_HUMAN
Heat shock 70 kDa protein 1B
Search

0.53	Inducible heat shock protein 70

0.52	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0010638	positive regulation of organelle organization
0.52	GO:0042026	protein refolding
0.50	GO:0010821	regulation of mitochondrion organization
0.50	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.50	GO:1903533	regulation of protein targeting
0.50	GO:0090316	positive regulation of intracellular protein transport
0.48	GO:0010968	regulation of microtubule nucleation
0.47	GO:1901673	regulation of mitotic spindle assembly
0.44	GO:0032273	positive regulation of protein polymerization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0031072	heat shock protein binding
0.47	GO:0051082	unfolded protein binding
0.41	GO:0055131	C3HC4-type RING finger domain binding
0.41	GO:0031249	denatured protein binding
0.41	GO:0001106	RNA polymerase II transcription corepressor activity

0.53	GO:0002199	zona pellucida receptor complex
0.49	GO:0044297	cell body
0.49	GO:0008180	COP9 signalosome
0.46	GO:0005829	cytosol
0.44	GO:0005813	centrosome
0.41	GO:0072562	blood microparticle
0.40	GO:0016235	aggresome
0.39	GO:0005814	centriole
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0070062	extracellular exosome

0.34	EC:6.1.1.9	GO:0004832
0.34	KEGG:R03665	GO:0004832

sp|P0DMW2|PYDC4_HUMAN
NLR family pyrin domain-containing protein 2B
Search

0.17	NLR family pyrin domain-containing protein 2B

0.74	GO:0050706	regulation of interleukin-1 beta secretion
0.72	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.65	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly
0.63	GO:0050711	negative regulation of interleukin-1 secretion
0.63	GO:0032691	negative regulation of interleukin-1 beta production
0.62	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.61	GO:0050716	positive regulation of interleukin-1 secretion
0.61	GO:0032731	positive regulation of interleukin-1 beta production
0.60	GO:0043065	positive regulation of apoptotic process
0.58	GO:2001056	positive regulation of cysteine-type endopeptidase activity

0.65	GO:0032090	Pyrin domain binding
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0000784	nuclear chromosome, telomeric region
0.52	GO:0005794	Golgi apparatus
0.50	GO:0005829	cytosol

sp|P0DMW3|SIML1_HUMAN
Small integral membrane protein 10-like protein 1
Search

0.97	Small integral membrane protein 10

0.30

GO:0044425

membrane part

sp|P0DMW4|SIL2A_HUMAN
Small integral membrane protein 10-like protein 2A
Search

0.97	small integral membrane protein 10

0.41	GO:0032012	regulation of ARF protein signal transduction
0.38	GO:0065009	regulation of molecular function

0.41

GO:0005086

ARF guanyl-nucleotide exchange factor activity

0.30

GO:0044425

membrane part

sp|P0DMW5|SIL2B_HUMAN
Small integral membrane protein 10-like protein 2B
Search

0.97	small integral membrane protein 10

0.41	GO:0032012	regulation of ARF protein signal transduction
0.38	GO:0065009	regulation of molecular function

0.41

GO:0005086

ARF guanyl-nucleotide exchange factor activity

0.30

GO:0044425

membrane part

sp|P0DN24|YC024_HUMAN
Putative uncharacterized protein LINC00694
Search

sp|P0DN25|C1C1L_HUMAN
C1GALT1-specific chaperone 1-like protein
Search

C1GALT1C1

0.97	Core 1 beta3-galactosyltransferase-specific molecular chaperone

0.66	GO:0006493	protein O-linked glycosylation
0.61	GO:0036344	platelet morphogenesis
0.58	GO:0030168	platelet activation

0.59	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity
0.34	GO:0005515	protein binding

0.39	GO:0070062	extracellular exosome
0.36	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.59

EC:2.4.1.122

GO:0016263

sp|P0DN26|PAL4F_HUMAN
Peptidyl-prolyl cis-trans isomerase A-like 4F
Search

PPIA

0.46	Peptidyl-prolyl cis-trans isomerase A

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.48	GO:0045069	regulation of viral genome replication
0.41	GO:0034389	lipid particle organization
0.40	GO:1903902	positive regulation of viral life cycle
0.40	GO:0050714	positive regulation of protein secretion
0.35	GO:0019061	uncoating of virus
0.35	GO:0030182	neuron differentiation
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0043312	neutrophil degranulation

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0016018	cyclosporin A binding
0.35	GO:0046790	virion binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.43	GO:0005829	cytosol
0.42	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.36	GO:0031982	vesicle
0.36	GO:0043209	myelin sheath
0.36	GO:0005925	focal adhesion
0.33	GO:0012505	endomembrane system
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|P0DN37|PAL4G_HUMAN
Peptidyl-prolyl cis-trans isomerase A-like 4G
Search

PPIA

0.48	Peptidyl-prolyl cis-trans isomerase A

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.49	GO:0045069	regulation of viral genome replication
0.41	GO:0034389	lipid particle organization
0.41	GO:1903902	positive regulation of viral life cycle
0.40	GO:0050714	positive regulation of protein secretion
0.36	GO:0019061	uncoating of virus
0.35	GO:0030182	neuron differentiation
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0043312	neutrophil degranulation

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0016018	cyclosporin A binding
0.35	GO:0046790	virion binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.43	GO:0005829	cytosol
0.42	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.36	GO:0031982	vesicle
0.36	GO:0043209	myelin sheath
0.36	GO:0005925	focal adhesion
0.33	GO:0012505	endomembrane system
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|P0DN76|U2AF5_HUMAN
Splicing factor U2AF 35 kDa subunit-like protein
Search

U2AF1

0.89	U2 small nuclear RNA auxiliary factor small subunit

0.75

GO:0000398

mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.47	GO:0050733	RS domain binding

0.84	GO:0089701	U2AF
0.48	GO:0005681	spliceosomal complex
0.43	GO:0016607	nuclear speck
0.30	GO:0016021	integral component of membrane

sp|P0DN77|OPSG2_HUMAN
Medium-wave-sensitive opsin 2
Search

0.90	Long wavelength sensitive visual pigment

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0009584	detection of visible light
0.39	GO:0032467	positive regulation of cytokinesis
0.37	GO:0016038	absorption of visible light
0.37	GO:0001523	retinoid metabolic process
0.36	GO:0070207	protein homotrimerization
0.35	GO:0016039	absorption of UV light

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.40	GO:0042802	identical protein binding
0.37	GO:0031404	chloride ion binding
0.34	GO:0046983	protein dimerization activity

0.53	GO:0001750	photoreceptor outer segment
0.38	GO:0098590	plasma membrane region
0.36	GO:0001917	photoreceptor inner segment
0.36	GO:0044297	cell body
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031982	vesicle
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005887	integral component of plasma membrane

sp|P0DN78|OPSG3_HUMAN
Medium-wave-sensitive opsin 3
Search

0.90	Long wavelength sensitive visual pigment

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0009584	detection of visible light
0.39	GO:0032467	positive regulation of cytokinesis
0.37	GO:0016038	absorption of visible light
0.37	GO:0001523	retinoid metabolic process
0.36	GO:0070207	protein homotrimerization
0.35	GO:0016039	absorption of UV light

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.40	GO:0042802	identical protein binding
0.37	GO:0031404	chloride ion binding
0.34	GO:0046983	protein dimerization activity

0.53	GO:0001750	photoreceptor outer segment
0.38	GO:0098590	plasma membrane region
0.36	GO:0001917	photoreceptor inner segment
0.36	GO:0044297	cell body
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031982	vesicle
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005887	integral component of plasma membrane

sp|P0DN79|CBSL_HUMAN
Cystathionine beta-synthase-like protein
Search

CBS

0.62	Cystathionine beta-synthase

0.84	GO:0019343	cysteine biosynthetic process via cystathionine
0.76	GO:0006535	cysteine biosynthetic process from serine
0.55	GO:0051593	response to folic acid
0.53	GO:0001958	endochondral ossification
0.53	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.53	GO:0001974	blood vessel remodeling
0.53	GO:0030823	regulation of cGMP metabolic process
0.52	GO:0021587	cerebellum morphogenesis
0.52	GO:0050667	homocysteine metabolic process
0.52	GO:0043506	regulation of JUN kinase activity

0.84	GO:0004122	cystathionine beta-synthase activity
0.42	GO:0070279	vitamin B6 binding
0.40	GO:0020037	heme binding
0.40	GO:0050662	coenzyme binding
0.39	GO:0070025	carbon monoxide binding
0.39	GO:0070026	nitric oxide binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0043168	anion binding
0.38	GO:0050421	nitrite reductase (NO-forming) activity
0.37	GO:0031625	ubiquitin protein ligase binding

0.49	GO:0005737	cytoplasm
0.37	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.84

EC:4.2.1.22

GO:0004122

sp|P0DN80|OR5H8_HUMAN
Olfactory receptor 5H8
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0DN81|O13C7_HUMAN
Olfactory receptor 13C7
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0DN82|O12D1_HUMAN
Olfactory receptor 12D1
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0DN84|DWORF_HUMAN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF
Search

0.93	Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

0.90	GO:1902082	positive regulation of calcium ion import into sarcoplasmic reticulum
0.88	GO:0031449	regulation of slow-twitch skeletal muscle fiber contraction
0.87	GO:1901894	regulation of calcium-transporting ATPase activity
0.73	GO:0043085	positive regulation of catalytic activity

0.74	GO:0008047	enzyme activator activity
0.52	GO:0005515	protein binding

0.85	GO:0033017	sarcoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0DN86|CGB3_HUMAN
Choriogonadotropin subunit beta 3
Search

0.97	Precursor chorionic gonadotropin beta subunit

0.76	GO:0010469	regulation of receptor activity
0.40	GO:0030728	ovulation
0.38	GO:0009755	hormone-mediated signaling pathway
0.38	GO:0007267	cell-cell signaling
0.37	GO:0007186	G-protein coupled receptor signaling pathway

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm

sp|P0DN87|CGB7_HUMAN
Choriogonadotropin subunit beta 7
Search

0.97	Precursor chorionic gonadotropin beta subunit

0.76	GO:0010469	regulation of receptor activity
0.40	GO:0030728	ovulation
0.38	GO:0009755	hormone-mediated signaling pathway
0.38	GO:0007267	cell-cell signaling
0.37	GO:0007186	G-protein coupled receptor signaling pathway

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm

sp|P0DO92|ENOL_HUMAN
Putative protein T-ENOL
Search

sp|P0DO97|CC192_HUMAN
Coiled-coil domain-containing protein 192
Search

CCDC192

0.97	Coiled-coil domain-containing protein 192

sp|P0DOY2|IGLC2_HUMAN
Immunoglobulin lambda constant 2
Search

0.97	Ig lambda chain C regions

0.75	GO:0006910	phagocytosis, recognition
0.75	GO:0002250	adaptive immune response
0.74	GO:0006911	phagocytosis, engulfment
0.74	GO:0050853	B cell receptor signaling pathway
0.73	GO:0050871	positive regulation of B cell activation
0.72	GO:0002449	lymphocyte mediated immunity
0.72	GO:0006956	complement activation
0.68	GO:0045087	innate immune response
0.67	GO:0042742	defense response to bacterium
0.51	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.79	GO:0003823	antigen binding
0.76	GO:0034987	immunoglobulin receptor binding
0.43	GO:0004252	serine-type endopeptidase activity

0.77	GO:0072562	blood microparticle
0.75	GO:0042571	immunoglobulin complex, circulating
0.70	GO:0009897	external side of plasma membrane
0.52	GO:0070062	extracellular exosome

0.43

GO:0004252

sp|P0DOY3|IGLC3_HUMAN
Immunoglobulin lambda constant 3
Search

0.97	Ig lambda chain C regions

0.75	GO:0006910	phagocytosis, recognition
0.75	GO:0002250	adaptive immune response
0.74	GO:0006911	phagocytosis, engulfment
0.74	GO:0050853	B cell receptor signaling pathway
0.73	GO:0050871	positive regulation of B cell activation
0.72	GO:0002449	lymphocyte mediated immunity
0.72	GO:0006956	complement activation
0.68	GO:0045087	innate immune response
0.67	GO:0042742	defense response to bacterium
0.51	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.79	GO:0003823	antigen binding
0.76	GO:0034987	immunoglobulin receptor binding
0.43	GO:0004252	serine-type endopeptidase activity

0.77	GO:0072562	blood microparticle
0.75	GO:0042571	immunoglobulin complex, circulating
0.70	GO:0009897	external side of plasma membrane
0.52	GO:0070062	extracellular exosome

0.43

GO:0004252

sp|P0DP01|HV108_HUMAN
Immunoglobulin heavy variable 1-8
Search

0.49	Immunoglobulin heavy variable 1-8

0.81	GO:0006958	complement activation, classical pathway
0.79	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.78	GO:0006909	phagocytosis
0.74	GO:0099024	plasma membrane invagination
0.73	GO:0050871	positive regulation of B cell activation
0.69	GO:0008037	cell recognition
0.68	GO:0045087	innate immune response
0.68	GO:0042742	defense response to bacterium
0.57	GO:0038094	Fc-gamma receptor signaling pathway
0.57	GO:0038095	Fc-epsilon receptor signaling pathway

0.83	GO:0003823	antigen binding
0.76	GO:0034987	immunoglobulin receptor binding
0.47	GO:0004252	serine-type endopeptidase activity

0.75	GO:0042571	immunoglobulin complex, circulating
0.74	GO:0072562	blood microparticle
0.71	GO:0009897	external side of plasma membrane
0.38	GO:0005887	integral component of plasma membrane

0.47

GO:0004252

sp|P0DP02|HVC33_HUMAN
Immunoglobulin heavy variable 3-30-3
Search

0.82	Immunoglobulin heavy variable 3-7

0.82	GO:0002250	adaptive immune response
0.76	GO:0002449	lymphocyte mediated immunity
0.76	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.76	GO:0006956	complement activation
0.75	GO:0006909	phagocytosis
0.70	GO:0038094	Fc-gamma receptor signaling pathway
0.70	GO:0038095	Fc-epsilon receptor signaling pathway
0.68	GO:0030449	regulation of complement activation
0.65	GO:0050900	leukocyte migration
0.62	GO:0099024	plasma membrane invagination

0.85	GO:0003823	antigen binding
0.64	GO:0034987	immunoglobulin receptor binding
0.56	GO:0004252	serine-type endopeptidase activity

0.67	GO:0072562	blood microparticle
0.63	GO:0042571	immunoglobulin complex, circulating
0.60	GO:0009897	external side of plasma membrane
0.53	GO:0070062	extracellular exosome

0.56

GO:0004252

sp|P0DP03|HV335_HUMAN
Immunoglobulin heavy variable 3-30-5
Search

0.83	Immunoglobulin heavy variable 3-7

0.82	GO:0002250	adaptive immune response
0.76	GO:0002449	lymphocyte mediated immunity
0.76	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.76	GO:0006956	complement activation
0.75	GO:0006909	phagocytosis
0.68	GO:0038094	Fc-gamma receptor signaling pathway
0.68	GO:0038095	Fc-epsilon receptor signaling pathway
0.66	GO:0030449	regulation of complement activation
0.65	GO:0099024	plasma membrane invagination
0.64	GO:0050871	positive regulation of B cell activation

0.85	GO:0003823	antigen binding
0.66	GO:0034987	immunoglobulin receptor binding
0.54	GO:0004252	serine-type endopeptidase activity

0.67	GO:0072562	blood microparticle
0.66	GO:0042571	immunoglobulin complex, circulating
0.62	GO:0009897	external side of plasma membrane
0.50	GO:0070062	extracellular exosome

0.54

GO:0004252

sp|P0DP04|HV43D_HUMAN
Immunoglobulin heavy variable 3-43D
Search

0.97	Immunoglobulin heavy variable 3-9

0.83	GO:0002250	adaptive immune response
0.80	GO:0002449	lymphocyte mediated immunity
0.80	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.80	GO:0006956	complement activation
0.79	GO:0006909	phagocytosis
0.74	GO:0099024	plasma membrane invagination
0.73	GO:0050871	positive regulation of B cell activation
0.70	GO:0008037	cell recognition
0.68	GO:0045087	innate immune response
0.68	GO:0042742	defense response to bacterium

0.85	GO:0003823	antigen binding
0.76	GO:0034987	immunoglobulin receptor binding
0.50	GO:0004252	serine-type endopeptidase activity

0.75	GO:0042571	immunoglobulin complex, circulating
0.74	GO:0072562	blood microparticle
0.71	GO:0009897	external side of plasma membrane
0.48	GO:0070062	extracellular exosome

0.50

GO:0004252

sp|P0DP06|HVD34_HUMAN
Immunoglobulin heavy variable 4-30-4
Search

0.88	Immunoglobulin heavy variable 4-4

0.83	GO:0002250	adaptive immune response
0.75	GO:0002449	lymphocyte mediated immunity
0.75	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.75	GO:0006956	complement activation
0.75	GO:0006909	phagocytosis
0.66	GO:0099024	plasma membrane invagination
0.65	GO:0050871	positive regulation of B cell activation
0.63	GO:0038094	Fc-gamma receptor signaling pathway
0.63	GO:0038095	Fc-epsilon receptor signaling pathway
0.62	GO:0008037	cell recognition

0.85	GO:0003823	antigen binding
0.67	GO:0034987	immunoglobulin receptor binding
0.51	GO:0004252	serine-type endopeptidase activity

0.67	GO:0042571	immunoglobulin complex, circulating
0.66	GO:0072562	blood microparticle
0.63	GO:0009897	external side of plasma membrane
0.47	GO:0070062	extracellular exosome

0.51

GO:0004252

sp|P0DP07|HV431_HUMAN
Immunoglobulin heavy variable 4-31
Search

0.92	Immunoglobulin heavy variable 4-4

0.81	GO:0002250	adaptive immune response
0.74	GO:0002449	lymphocyte mediated immunity
0.74	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.74	GO:0006956	complement activation
0.74	GO:0006909	phagocytosis
0.66	GO:0099024	plasma membrane invagination
0.65	GO:0050871	positive regulation of B cell activation
0.62	GO:0008037	cell recognition
0.61	GO:0045087	innate immune response
0.61	GO:0038094	Fc-gamma receptor signaling pathway

0.84	GO:0003823	antigen binding
0.67	GO:0034987	immunoglobulin receptor binding
0.50	GO:0004252	serine-type endopeptidase activity

0.67	GO:0042571	immunoglobulin complex, circulating
0.66	GO:0072562	blood microparticle
0.63	GO:0009897	external side of plasma membrane
0.46	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.50

GO:0004252

sp|P0DP08|HVD82_HUMAN
Immunoglobulin heavy variable 4-38-2
Search

0.81	Immunoglobulin heavy variable 4-4

0.83	GO:0002250	adaptive immune response
0.74	GO:0002449	lymphocyte mediated immunity
0.74	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.73	GO:0006956	complement activation
0.73	GO:0006909	phagocytosis
0.64	GO:0099024	plasma membrane invagination
0.64	GO:0050871	positive regulation of B cell activation
0.62	GO:0038094	Fc-gamma receptor signaling pathway
0.62	GO:0038095	Fc-epsilon receptor signaling pathway
0.61	GO:0008037	cell recognition

0.85	GO:0003823	antigen binding
0.66	GO:0034987	immunoglobulin receptor binding
0.51	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005576	extracellular region
0.65	GO:0019814	immunoglobulin complex
0.62	GO:0009897	external side of plasma membrane
0.43	GO:0031982	vesicle

0.51

GO:0004252

sp|P0DP09|KV113_HUMAN
Immunoglobulin kappa variable 1-13
Search

0.97	Immunoglobulin kappa variable 1-9

0.78	GO:0002250	adaptive immune response
0.73	GO:0002377	immunoglobulin production
0.70	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.69	GO:0038095	Fc-epsilon receptor signaling pathway
0.67	GO:0030449	regulation of complement activation
0.65	GO:0002449	lymphocyte mediated immunity
0.65	GO:0006956	complement activation
0.64	GO:0050900	leukocyte migration
0.57	GO:0006898	receptor-mediated endocytosis
0.50	GO:0006508	proteolysis

0.81	GO:0003823	antigen binding
0.55	GO:0004252	serine-type endopeptidase activity
0.39	GO:0042802	identical protein binding

0.70	GO:0005615	extracellular space
0.59	GO:1903561	extracellular vesicle
0.53	GO:0005886	plasma membrane

0.55

GO:0004252

sp|P10070|GLI2_HUMAN
Zinc finger protein GLI2
Search

GLI2

0.74	zinc finger protein GLI2

0.52	GO:0060032	notochord regression
0.52	GO:0021508	floor plate formation
0.52	GO:0021965	spinal cord ventral commissure morphogenesis
0.51	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification
0.51	GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
0.51	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
0.51	GO:0060513	prostatic bud formation
0.51	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.50	GO:0002076	osteoblast development
0.50	GO:0032331	negative regulation of chondrocyte differentiation

0.51	GO:0003676	nucleic acid binding
0.49	GO:1990841	promoter-specific chromatin binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0008134	transcription factor binding
0.41	GO:0008270	zinc ion binding

0.50	GO:0097542	ciliary tip
0.48	GO:0005930	axoneme
0.47	GO:0016607	nuclear speck
0.47	GO:0031514	motile cilium
0.45	GO:0005730	nucleolus
0.39	GO:0005829	cytosol
0.34	GO:0097730	non-motile cilium
0.30	GO:0097546	ciliary base
0.30	GO:0016020	membrane

sp|P10071|GLI3_HUMAN
Transcriptional activator GLI3
Search

GLI3

0.87	GLI family zinc finger 3

0.83	GO:0007224	smoothened signaling pathway
0.83	GO:0009953	dorsal/ventral pattern formation
0.81	GO:0009952	anterior/posterior pattern specification
0.79	GO:0048568	embryonic organ development
0.78	GO:0022018	lateral ganglionic eminence cell proliferation
0.78	GO:0060873	anterior semicircular canal development
0.78	GO:0060366	lambdoid suture morphogenesis
0.78	GO:0060367	sagittal suture morphogenesis
0.78	GO:0060875	lateral semicircular canal development
0.77	GO:0060364	frontal suture morphogenesis

0.74	GO:0035035	histone acetyltransferase binding
0.71	GO:0042826	histone deacetylase binding
0.70	GO:0008013	beta-catenin binding
0.69	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0003682	chromatin binding
0.61	GO:0003700	DNA binding transcription factor activity
0.39	GO:0008134	transcription factor binding
0.37	GO:0008270	zinc ion binding
0.32	GO:0004601	peroxidase activity
0.31	GO:0020037	heme binding

0.69	GO:0005930	axoneme
0.68	GO:0016607	nuclear speck
0.67	GO:0017053	transcriptional repressor complex
0.65	GO:0016592	mediator complex
0.59	GO:0005829	cytosol
0.43	GO:0097542	ciliary tip
0.41	GO:0031514	motile cilium
0.39	GO:0005730	nucleolus
0.38	GO:0097730	non-motile cilium
0.30	GO:0016020	membrane

0.32	EC:1.11.1.7	GO:0004601
0.32	KEGG:R03532	GO:0004601

sp|P10072|HKR1_HUMAN
Krueppel-related zinc finger protein 1
Search

ZNF169

0.69	Zinc finger protein 169

0.60	GO:0034968	histone lysine methylation
0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.30	GO:0007275	multicellular organism development

0.60	GO:0018024	histone-lysine N-methyltransferase activity
0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0003700	DNA binding transcription factor activity

0.41	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle

0.60

EC:2.1.1.43

GO:0018024

sp|P10073|ZSC22_HUMAN
Zinc finger and SCAN domain-containing protein 22
Search

0.55	Zinc finger and SCAN domain-containing protein 22

0.57	GO:0097659	nucleic acid-templated transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0010467	gene expression
0.52	GO:0034645	cellular macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.30	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|P10074|TZAP_HUMAN
Telomere zinc finger-associated protein
Search

ZBTB48

0.95	Zinc finger and BTB domain-containing protein 48

0.59	GO:0010833	telomere maintenance via telomere lengthening
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:1902070	positive regulation of sphingolipid mediated signaling pathway
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0034224	cellular response to zinc ion starvation
0.32	GO:0043620	regulation of DNA-templated transcription in response to stress

0.60	GO:0003691	double-stranded telomeric DNA binding
0.54	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0042802	identical protein binding
0.41	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0046872	metal ion binding
0.34	GO:0003682	chromatin binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:1990837	sequence-specific double-stranded DNA binding
0.32	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding

0.55	GO:0000781	chromosome, telomeric region
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0045111	intermediate filament cytoskeleton
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P10075|GLI4_HUMAN
Zinc finger protein GLI4
Search

GLI4

0.96	GLI family zinc finger 4

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.38	GO:0071294	cellular response to zinc ion
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0042254	ribosome biogenesis
0.34	GO:1902680	positive regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.42	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part

sp|P10082|PYY_HUMAN
Peptide YY
Search

PYY

0.93	pro-neuropeptide Y

0.76	GO:0010469	regulation of receptor activity
0.59	GO:0007218	neuropeptide signaling pathway
0.54	GO:0032098	regulation of appetite
0.54	GO:0007631	feeding behavior
0.52	GO:0007586	digestion
0.49	GO:0007267	cell-cell signaling
0.37	GO:0008217	regulation of blood pressure
0.37	GO:0032096	negative regulation of response to food
0.37	GO:0008283	cell proliferation
0.36	GO:0007010	cytoskeleton organization

0.79	GO:0005179	hormone activity
0.51	GO:0001664	G-protein coupled receptor binding
0.35	GO:0090729	toxin activity
0.34	GO:0005516	calmodulin binding

0.66	GO:0005576	extracellular region
0.34	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|P10092|CALCB_HUMAN
Calcitonin gene-related peptide 2
Search

0.96	Calcitonin receptor-stimulating peptide 2

0.76	GO:0010469	regulation of receptor activity
0.47	GO:0055074	calcium ion homeostasis
0.46	GO:0001984	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
0.45	GO:0007190	activation of adenylate cyclase activity
0.45	GO:0045779	negative regulation of bone resorption
0.44	GO:0031645	negative regulation of neurological system process
0.44	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.44	GO:0045986	negative regulation of smooth muscle contraction
0.44	GO:1990090	cellular response to nerve growth factor stimulus
0.44	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway

0.79	GO:0005179	hormone activity
0.46	GO:0031716	calcitonin receptor binding
0.40	GO:0042802	identical protein binding
0.36	GO:0032403	protein complex binding

0.66	GO:0005576	extracellular region
0.43	GO:0043195	terminal bouton
0.42	GO:0043025	neuronal cell body
0.35	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P10109|ADX_HUMAN
Adrenodoxin, mitochondrial
Search

FDX1

0.61	Adrenodoxin, mitochondrial

0.61	GO:0022900	electron transport chain
0.55	GO:1904321	response to forskolin
0.54	GO:0071320	cellular response to cAMP
0.53	GO:1901655	cellular response to ketone
0.53	GO:0008203	cholesterol metabolic process
0.51	GO:0035690	cellular response to drug
0.51	GO:0042446	hormone biosynthetic process
0.50	GO:0071396	cellular response to lipid
0.44	GO:1904087	negative regulation of epiboly involved in gastrulation with mouth forming second
0.41	GO:0006694	steroid biosynthetic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.35	GO:0046872	metal ion binding
0.35	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.35	GO:0015039	NADPH-adrenodoxin reductase activity
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0019899	enzyme binding

0.44	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0044425	membrane part

0.35

EC:1.14.15.6

GO:0008386

sp|P10114|RAP2A_HUMAN
Ras-related protein Rap-2a
Search

RAP2A

0.87	RAP2A, member of RAS oncogene family a

0.66	GO:0032486	Rap protein signal transduction
0.65	GO:0031954	positive regulation of protein autophosphorylation
0.61	GO:0030336	negative regulation of cell migration
0.58	GO:0061097	regulation of protein tyrosine kinase activity
0.53	GO:0090557	establishment of endothelial intestinal barrier
0.52	GO:0070527	platelet aggregation
0.51	GO:0030033	microvillus assembly
0.48	GO:0048814	regulation of dendrite morphogenesis
0.48	GO:0046328	regulation of JNK cascade
0.47	GO:0072659	protein localization to plasma membrane

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0003713	transcription coactivator activity
0.47	GO:0019904	protein domain specific binding
0.41	GO:0000287	magnesium ion binding

0.64	GO:0055038	recycling endosome membrane
0.59	GO:0044291	cell-cell contact zone
0.57	GO:0005923	bicellular tight junction
0.53	GO:0005829	cytosol
0.50	GO:0070062	extracellular exosome
0.49	GO:0045121	membrane raft
0.46	GO:0005886	plasma membrane
0.38	GO:0030496	midbody
0.36	GO:0070821	tertiary granule membrane
0.35	GO:0035579	specific granule membrane

sp|P10124|SRGN_HUMAN
Serglycin
Search

SRGN

0.97

Serglycin

0.87	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.86	GO:0030502	negative regulation of bone mineralization
0.75	GO:0033366	protein localization to secretory granule
0.75	GO:0033364	mast cell secretory granule organization
0.65	GO:0033371	T cell secretory granule organization
0.59	GO:0050710	negative regulation of cytokine secretion
0.56	GO:0051651	maintenance of location in cell
0.56	GO:0045185	maintenance of protein location
0.53	GO:0016485	protein processing
0.50	GO:0031214	biomineral tissue development

0.42	GO:0005515	protein binding
0.37	GO:0044877	macromolecular complex binding

0.73	GO:0005615	extracellular space
0.71	GO:0005794	Golgi apparatus
0.60	GO:0042629	mast cell granule
0.47	GO:0031093	platelet alpha granule lumen
0.40	GO:0042588	zymogen granule
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment

sp|P10144|GRAB_HUMAN
Granzyme B
Search

0.95	Endogenous granzyme B

0.70	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.67	GO:0001909	leukocyte mediated cytotoxicity
0.65	GO:0002228	natural killer cell mediated immunity
0.61	GO:0006508	proteolysis
0.44	GO:0051873	killing by host of symbiont cells
0.43	GO:0044130	negative regulation of growth of symbiont in host
0.43	GO:0002446	neutrophil mediated immunity
0.43	GO:0019731	antibacterial humoral response
0.42	GO:0050830	defense response to Gram-positive bacterium
0.42	GO:0071222	cellular response to lipopolysaccharide

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0008201	heparin binding
0.35	GO:0005515	protein binding

0.66	GO:0030141	secretory granule
0.41	GO:0010494	cytoplasmic stress granule
0.40	GO:0031012	extracellular matrix
0.40	GO:0005615	extracellular space
0.38	GO:0044194	cytolytic granule
0.36	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol
0.34	GO:0005766	primary lysosome
0.34	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P10145|IL8_HUMAN
Interleukin-8
Search

CXCL8

0.46	Multifunctional fusion protein (Fragment)

0.85	GO:0042119	neutrophil activation
0.85	GO:0030593	neutrophil chemotaxis
0.79	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.63	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.62	GO:0050930	induction of positive chemotaxis
0.61	GO:2000535	regulation of entry of bacterium into host cell
0.58	GO:0048566	embryonic digestive tract development
0.58	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway

0.86	GO:0005153	interleukin-8 receptor binding
0.84	GO:0008009	chemokine activity
0.34	GO:0008083	growth factor activity

0.73	GO:0005615	extracellular space
0.38	GO:0005622	intracellular

sp|P10147|CCL3_HUMAN
C-C motif chemokine 3
Search

0.74	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.60	GO:0097529	myeloid leukocyte migration
0.59	GO:0071674	mononuclear cell migration
0.58	GO:0072676	lymphocyte migration
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.55	GO:0043615	astrocyte cell migration
0.55	GO:0006954	inflammatory response
0.55	GO:0071347	cellular response to interleukin-1

0.84	GO:0008009	chemokine activity
0.58	GO:0048020	CCR chemokine receptor binding
0.53	GO:0004698	calcium-dependent protein kinase C activity
0.52	GO:0016004	phospholipase activator activity
0.51	GO:0042056	chemoattractant activity
0.41	GO:0042802	identical protein binding
0.37	GO:0008201	heparin binding
0.34	GO:0045236	CXCR chemokine receptor binding
0.33	GO:0003735	structural constituent of ribosome

0.71	GO:0005615	extracellular space
0.44	GO:0005829	cytosol
0.34	GO:0015934	large ribosomal subunit
0.32	GO:0043234	protein complex

0.53

GO:0004698

sp|P10153|RNAS2_HUMAN
Non-secretory ribonuclease
Search

0.97	Non-secretory ribonuclease

0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.47	GO:0098542	defense response to other organism
0.47	GO:0002252	immune effector process
0.47	GO:0009615	response to virus
0.46	GO:1903955	positive regulation of protein targeting to mitochondrion
0.44	GO:0016070	RNA metabolic process
0.42	GO:0019730	antimicrobial humoral response
0.42	GO:0006935	chemotaxis
0.40	GO:0009617	response to bacterium
0.40	GO:0002227	innate immune response in mucosa

0.64	GO:0004519	endonuclease activity
0.52	GO:0004540	ribonuclease activity
0.51	GO:0003676	nucleic acid binding
0.42	GO:0001530	lipopolysaccharide binding

0.50	GO:0005764	lysosome
0.41	GO:0005576	extracellular region
0.39	GO:0031982	vesicle
0.39	GO:0005775	vacuolar lumen
0.36	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

sp|P10155|RO60_HUMAN
60 kDa SS-A/Ro ribonucleoprotein
Search

TROVE2

0.93	Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro)

0.56	GO:0007224	smoothened signaling pathway
0.55	GO:0009411	response to UV
0.54	GO:0060271	cilium assembly
0.53	GO:0002520	immune system development
0.35	GO:0006383	transcription by RNA polymerase III
0.33	GO:0006508	proteolysis
0.31	GO:0055114	oxidation-reduction process

0.60	GO:0030620	U2 snRNA binding
0.39	GO:0034336	misfolded RNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0008233	peptidase activity
0.31	GO:0016491	oxidoreductase activity

0.59	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008233

sp|P10163|PRB4_HUMAN
Basic salivary proline-rich protein 4
Search

0.96	Basic salivary proline-rich protein 4

0.46	GO:0050829	defense response to Gram-negative bacterium
0.40	GO:0006888	ER to Golgi vesicle-mediated transport
0.39	GO:0010469	regulation of receptor activity
0.38	GO:0006886	intracellular protein transport
0.38	GO:0006508	proteolysis
0.37	GO:0035987	endodermal cell differentiation
0.36	GO:0006470	protein dephosphorylation
0.36	GO:0061890	positive regulation of astrocyte activation
0.36	GO:0009405	pathogenesis
0.36	GO:1903980	positive regulation of microglial cell activation

0.40	GO:0008270	zinc ion binding
0.40	GO:0005515	protein binding
0.39	GO:0004222	metalloendopeptidase activity
0.39	GO:0030545	receptor regulator activity
0.37	GO:0004722	protein serine/threonine phosphatase activity
0.35	GO:0003723	RNA binding
0.35	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.35	GO:0008144	drug binding
0.35	GO:0033293	monocarboxylic acid binding
0.34	GO:0004672	protein kinase activity

0.56	GO:0005576	extracellular region
0.41	GO:0030127	COPII vesicle coat
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0045298	tubulin complex
0.35	GO:0031981	nuclear lumen
0.35	GO:0000781	chromosome, telomeric region
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0033202	DNA helicase complex
0.34	GO:0000785	chromatin
0.34	GO:0005829	cytosol

0.39

GO:0004222

sp|P10176|COX8A_HUMAN
Cytochrome c oxidase subunit 8A, mitochondrial
Search

COX8A

0.97	Cytochrome c oxidase polypeptide VIII-liver/heart

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.43	GO:0006119	oxidative phosphorylation
0.43	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.36	GO:0005515	protein binding

0.55	GO:0005739	mitochondrion
0.55	GO:0019866	organelle inner membrane
0.47	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P10242|MYB_HUMAN
Transcriptional activator Myb
Search

MYB

0.89	Transcriptional activator Myb

0.58	GO:0045624	positive regulation of T-helper cell differentiation
0.58	GO:0051574	positive regulation of histone H3-K9 methylation
0.57	GO:0051571	positive regulation of histone H3-K4 methylation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0006338	chromatin remodeling
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.54	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0071987	WD40-repeat domain binding

0.40	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P10243|MYBA_HUMAN
Myb-related protein A
Search

MYBL1

0.97	MYB proto-oncogene like 1

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.53	GO:0006366	transcription by RNA polymerase II
0.47	GO:0000278	mitotic cell cycle
0.46	GO:0030154	cell differentiation
0.42	GO:1990511	piRNA biosynthetic process

0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.32	GO:0071987	WD40-repeat domain binding

0.43	GO:0005634	nucleus
0.33	GO:0000785	chromatin
0.31	GO:0005829	cytosol
0.31	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

sp|P10244|MYBB_HUMAN
Myb-related protein B
Search

MYBL2

0.97	MYB proto-oncogene like 2

0.57	GO:0090307	mitotic spindle assembly
0.56	GO:1990830	cellular response to leukemia inhibitory factor
0.54	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0030154	cell differentiation
0.40	GO:0043525	positive regulation of neuron apoptotic process
0.35	GO:0051726	regulation of cell cycle
0.35	GO:1990511	piRNA biosynthetic process
0.34	GO:0010529	negative regulation of transposition
0.34	GO:0007141	male meiosis I

0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.35	GO:0005515	protein binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0005524	ATP binding

0.59	GO:0031523	Myb complex
0.50	GO:0005654	nucleoplasm

0.34

GO:0004674

sp|P10253|LYAG_HUMAN
Lysosomal alpha-glucosidase
Search

GAA

0.90	Lysosomal alpha-glucosidase

0.62	GO:0043181	vacuolar sequestering
0.61	GO:0002086	diaphragm contraction
0.60	GO:0005975	carbohydrate metabolic process
0.58	GO:0050884	neuromuscular process controlling posture
0.58	GO:0002026	regulation of the force of heart contraction
0.57	GO:0046716	muscle cell cellular homeostasis
0.57	GO:0060048	cardiac muscle contraction
0.57	GO:0050885	neuromuscular process controlling balance
0.56	GO:0007040	lysosome organization
0.55	GO:0003007	heart morphogenesis

0.69	GO:0030246	carbohydrate binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.54	GO:0005764	lysosome
0.40	GO:0098852	lytic vacuole membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0070821	tertiary granule membrane
0.36	GO:0005775	vacuolar lumen
0.33	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004553

sp|P10266|POK10_HUMAN
Endogenous retrovirus group K member 10 Pol protein
Search

0.96	Endogenous retrovirus group K member 7 Pol protein

0.68	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.67	GO:0006278	RNA-dependent DNA biosynthetic process
0.66	GO:0015074	DNA integration
0.61	GO:0006310	DNA recombination
0.46	GO:0045026	plasma membrane fusion
0.35	GO:0016032	viral process
0.35	GO:0006508	proteolysis

0.71	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.67	GO:0003964	RNA-directed DNA polymerase activity
0.61	GO:0008270	zinc ion binding
0.53	GO:0003677	DNA binding
0.46	GO:0005198	structural molecule activity
0.36	GO:0003887	DNA-directed DNA polymerase activity
0.36	GO:0070001	aspartic-type peptidase activity
0.35	GO:0004175	endopeptidase activity
0.34	GO:0003723	RNA binding

0.48	GO:0036338	viral membrane
0.40	GO:0005886	plasma membrane
0.35	GO:0019028	viral capsid
0.30	GO:0016021	integral component of membrane

0.71

EC:3.1.26.4

GO:0004523

sp|P10275|ANDR_HUMAN
Androgen receptor
Search

0.80	Androgen receptor splice variant 5

0.82	GO:0030521	androgen receptor signaling pathway
0.60	GO:0045720	negative regulation of integrin biosynthetic process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.55	GO:1903076	regulation of protein localization to plasma membrane
0.55	GO:0006351	transcription, DNA-templated
0.53	GO:0045726	positive regulation of integrin biosynthetic process
0.53	GO:0019102	male somatic sex determination

0.84	GO:0004882	androgen receptor activity
0.77	GO:0005496	steroid binding
0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0005497	androgen binding
0.60	GO:0008270	zinc ion binding
0.54	GO:0008013	beta-catenin binding
0.53	GO:0070974	POU domain binding
0.51	GO:0044212	transcription regulatory region DNA binding
0.51	GO:0051117	ATPase binding
0.50	GO:0001085	RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.49	GO:0000785	chromatin
0.47	GO:0070013	intracellular organelle lumen
0.41	GO:0043234	protein complex
0.39	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|P10276|RARA_HUMAN
Retinoic acid receptor alpha
Search

RARA

0.93	Retinoic acid receptor alpha

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0060010	Sertoli cell fate commitment
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.55	GO:0060591	chondroblast differentiation
0.55	GO:0060534	trachea cartilage development

0.85	GO:0003708	retinoic acid receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.54	GO:0043422	protein kinase B binding
0.54	GO:0001972	retinoic acid binding
0.53	GO:0051393	alpha-actinin binding
0.52	GO:0051018	protein kinase A binding
0.51	GO:0031490	chromatin DNA binding
0.50	GO:0003714	transcription corepressor activity

0.61	GO:0005634	nucleus
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.47	GO:0015629	actin cytoskeleton
0.47	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.45	GO:0070013	intracellular organelle lumen
0.39	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

sp|P10301|RRAS_HUMAN
Ras-related protein R-Ras
Search

RRAS

0.95	Harvey rat sarcoma oncogene, subgroup R

0.61	GO:0007165	signal transduction
0.57	GO:0030334	regulation of cell migration
0.55	GO:0060325	face morphogenesis
0.54	GO:0051896	regulation of protein kinase B signaling
0.54	GO:0045766	positive regulation of angiogenesis
0.53	GO:0070372	regulation of ERK1 and ERK2 cascade
0.53	GO:2000146	negative regulation of cell motility
0.53	GO:0002521	leukocyte differentiation
0.47	GO:1901214	regulation of neuron death
0.47	GO:2000147	positive regulation of cell motility

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0032403	protein complex binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0005198	structural molecule activity

0.39	GO:0005925	focal adhesion
0.39	GO:0070062	extracellular exosome
0.36	GO:0005622	intracellular
0.35	GO:0005886	plasma membrane
0.34	GO:0012505	endomembrane system
0.34	GO:0012506	vesicle membrane
0.34	GO:0048475	coated membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0098796	membrane protein complex

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P10323|ACRO_HUMAN
Acrosin
Search

ACR

0.97

Acrosin-a

0.59	GO:0006508	proteolysis
0.58	GO:0007190	activation of adenylate cyclase activity
0.57	GO:0007340	acrosome reaction
0.55	GO:0007341	penetration of zona pellucida
0.53	GO:0007339	binding of sperm to zona pellucida
0.39	GO:0048545	response to steroid hormone
0.35	GO:0044257	cellular protein catabolic process
0.34	GO:0006898	receptor-mediated endocytosis

0.67	GO:0004252	serine-type endopeptidase activity
0.57	GO:0005537	mannose binding
0.46	GO:0042806	fucose binding
0.42	GO:0004040	amidase activity
0.37	GO:0002020	protease binding
0.37	GO:0005507	copper ion binding
0.37	GO:0008144	drug binding
0.35	GO:0008270	zinc ion binding
0.35	GO:0005044	scavenger receptor activity
0.33	GO:0003677	DNA binding

0.79	GO:0001669	acrosomal vesicle
0.44	GO:0044437	vacuolar part
0.44	GO:0044433	cytoplasmic vesicle part
0.43	GO:0043234	protein complex
0.39	GO:0005798	Golgi-associated vesicle
0.35	GO:0005634	nucleus
0.35	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.67

GO:0004252

sp|P10398|ARAF_HUMAN
Serine/threonine-protein kinase A-Raf
Search

ARAF

0.97	A-Raf proto-oncogene serine/threonine-protein kinase

0.64	GO:0020021	immortalization of host cell
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.54	GO:0000186	activation of MAPKK activity
0.53	GO:0009968	negative regulation of signal transduction
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.51	GO:0043066	negative regulation of apoptotic process
0.50	GO:1900107	regulation of nodal signaling pathway
0.48	GO:0030154	cell differentiation
0.48	GO:0007167	enzyme linked receptor protein signaling pathway

0.77	GO:0005057	signal transducer activity, downstream of receptor
0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0031434	mitogen-activated protein kinase kinase binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.48	GO:0046332	SMAD binding
0.39	GO:0017016	Ras GTPase binding
0.39	GO:0042802	identical protein binding

0.48	GO:0005739	mitochondrion
0.47	GO:0005829	cytosol
0.42	GO:0031143	pseudopodium
0.40	GO:0016607	nuclear speck
0.39	GO:0005794	Golgi apparatus
0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.69

GO:0004674

sp|P10412|H14_HUMAN
Histone H1.4
Search

0.97	Histone cluster 1 H1 family member e

0.79	GO:0006334	nucleosome assembly
0.57	GO:0098532	histone H3-K27 trimethylation
0.55	GO:0080182	histone H3-K4 trimethylation
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.54	GO:0016584	nucleosome positioning
0.47	GO:0071169	establishment of protein localization to chromatin
0.47	GO:0051574	positive regulation of histone H3-K9 methylation
0.45	GO:0030307	positive regulation of cell growth
0.44	GO:0050821	protein stabilization
0.43	GO:0048260	positive regulation of receptor-mediated endocytosis

0.66	GO:0031490	chromatin DNA binding
0.45	GO:0042826	histone deacetylase binding
0.42	GO:0032564	dATP binding
0.42	GO:0008201	heparin binding
0.39	GO:0016208	AMP binding
0.38	GO:0043531	ADP binding
0.38	GO:0003690	double-stranded DNA binding
0.37	GO:0005509	calcium ion binding
0.37	GO:0003723	RNA binding
0.37	GO:0032550	purine ribonucleoside binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.58	GO:0000791	euchromatin
0.55	GO:0031974	membrane-enclosed lumen
0.54	GO:0000792	heterochromatin
0.49	GO:0035327	transcriptionally active chromatin
0.42	GO:0031982	vesicle
0.40	GO:0009986	cell surface
0.39	GO:0043230	extracellular organelle
0.38	GO:0005615	extracellular space

sp|P10415|BCL2_HUMAN
Apoptosis regulator Bcl-2
Search

BCL2

0.86	3-ketodihydrosphingosine reductase

0.78	GO:0043066	negative regulation of apoptotic process
0.74	GO:0006915	apoptotic process
0.64	GO:0032848	negative regulation of cellular pH reduction
0.64	GO:0043375	CD8-positive, alpha-beta T cell lineage commitment
0.63	GO:0014042	positive regulation of neuron maturation
0.63	GO:0021747	cochlear nucleus development
0.63	GO:0002326	B cell lineage commitment
0.62	GO:0046671	negative regulation of retinal cell programmed cell death
0.62	GO:0045636	positive regulation of melanocyte differentiation
0.62	GO:0038034	signal transduction in absence of ligand

0.62	GO:0051434	BH3 domain binding
0.60	GO:0051721	protein phosphatase 2A binding
0.57	GO:0002020	protease binding
0.57	GO:0016248	channel inhibitor activity
0.55	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0042803	protein homodimerization activity
0.52	GO:0008134	transcription factor binding
0.49	GO:0022803	passive transmembrane transporter activity
0.47	GO:0043565	sequence-specific DNA binding

0.57	GO:0043209	myelin sheath
0.57	GO:0031965	nuclear membrane
0.56	GO:0005741	mitochondrial outer membrane
0.53	GO:0046930	pore complex
0.52	GO:0005789	endoplasmic reticulum membrane
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0097136	Bcl-2 family protein complex
0.33	GO:0005813	centrosome

0.31

GO:0016491

sp|P10451|OSTP_HUMAN
Osteopontin
Search

SPP1

0.96	Secreted phosphoprotein 1

0.82	GO:0001503	ossification
0.72	GO:0007155	cell adhesion
0.67	GO:0006710	androgen catabolic process
0.67	GO:2000866	positive regulation of estradiol secretion
0.66	GO:0071394	cellular response to testosterone stimulus
0.65	GO:0033280	response to vitamin D
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.54	GO:0045780	positive regulation of bone resorption
0.46	GO:0030154	cell differentiation
0.45	GO:0031214	biomineral tissue development

0.50	GO:0050840	extracellular matrix binding
0.44	GO:0005125	cytokine activity
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004872	receptor activity
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.32	GO:0000996	promoter selection factor activity

0.57	GO:0005615	extracellular space
0.57	GO:0005794	Golgi apparatus
0.41	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle
0.39	GO:0042995	cell projection
0.38	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0045177	apical part of cell
0.32	GO:0032040	small-subunit processome
0.30	GO:0016020	membrane

0.32

EC:2.7.7.6

GO:0003899

sp|P10515|ODP2_HUMAN
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
Search

0.39	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

0.67	GO:0006090	pyruvate metabolic process
0.35	GO:0006006	glucose metabolic process
0.35	GO:0006099	tricarboxylic acid cycle
0.30	GO:0051196	regulation of coenzyme metabolic process
0.30	GO:0071616	acyl-CoA biosynthetic process
0.30	GO:0010565	regulation of cellular ketone metabolic process
0.30	GO:0032501	multicellular organismal process
0.30	GO:0006807	nitrogen compound metabolic process
0.30	GO:0031326	regulation of cellular biosynthetic process
0.30	GO:0080090	regulation of primary metabolic process

0.79	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity
0.30	GO:0005515	protein binding
0.30	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors

0.77	GO:0045254	pyruvate dehydrogenase complex
0.72	GO:0005759	mitochondrial matrix
0.30	GO:0043209	myelin sheath

0.79

EC:2.3.1.12

GO:0004742

sp|P10523|ARRS_HUMAN
S-arrestin
Search

SAG

0.97	S-antigen visual arrestin

0.61	GO:0007165	signal transduction
0.37	GO:0007601	visual perception
0.36	GO:0009416	response to light stimulus
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0031399	regulation of protein modification process
0.36	GO:0019220	regulation of phosphate metabolic process
0.35	GO:0071478	cellular response to radiation
0.35	GO:0009582	detection of abiotic stimulus
0.35	GO:0009581	detection of external stimulus
0.34	GO:0051346	negative regulation of hydrolase activity

0.60	GO:0002046	opsin binding
0.55	GO:0051219	phosphoprotein binding
0.37	GO:0030507	spectrin binding
0.35	GO:0042802	identical protein binding
0.35	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0004143	diacylglycerol kinase activity
0.34	GO:0003951	NAD+ kinase activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.57	GO:0001750	photoreceptor outer segment
0.57	GO:0001917	photoreceptor inner segment
0.35	GO:0005829	cytosol
0.35	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.1.107	GO:0004143
0.34	KEGG:R00104	GO:0003951

sp|P10586|PTPRF_HUMAN
Receptor-type tyrosine-protein phosphatase F
Search

PTPRF

0.94	Receptor-type tyrosine-protein phosphatase F

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.54	GO:1900121	negative regulation of receptor binding
0.54	GO:0031102	neuron projection regeneration
0.53	GO:0048679	regulation of axon regeneration
0.49	GO:0016477	cell migration
0.37	GO:0007155	cell adhesion
0.36	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway
0.36	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway
0.35	GO:0050775	positive regulation of dendrite morphogenesis
0.35	GO:0043525	positive regulation of neuron apoptotic process

0.75	GO:0004725	protein tyrosine phosphatase activity
0.57	GO:0035373	chondroitin sulfate proteoglycan binding
0.48	GO:0032403	protein complex binding
0.39	GO:0008201	heparin binding
0.38	GO:0019198	transmembrane receptor protein phosphatase activity
0.35	GO:0030971	receptor tyrosine kinase binding
0.34	GO:0042301	phosphate ion binding
0.34	GO:0046872	metal ion binding

0.51	GO:0043025	neuronal cell body
0.49	GO:0043005	neuron projection
0.36	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.35	GO:0060076	excitatory synapse
0.35	GO:0030427	site of polarized growth
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005768	endosome
0.34	GO:0005887	integral component of plasma membrane

0.75

EC:3.1.3.48

GO:0004725

sp|P10588|NR2F6_HUMAN
Nuclear receptor subfamily 2 group F member 6
Search

NR2F6

0.86	Estrogen receptor

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.54	GO:0043153	entrainment of circadian clock by photoperiod
0.49	GO:0048666	neuron development
0.47	GO:1902679	negative regulation of RNA biosynthetic process

0.81	GO:0004879	nuclear receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.52	GO:0035326	enhancer binding
0.52	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol

sp|P10589|COT1_HUMAN
COUP transcription factor 1
Search

0.94	Ovalbumin upstream promoter-transcription factor I

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060838	lymphatic endothelial cell fate commitment
0.49	GO:0051253	negative regulation of RNA metabolic process
0.49	GO:0010558	negative regulation of macromolecule biosynthetic process
0.49	GO:0001568	blood vessel development

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.49	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0001972	retinoic acid binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.44	GO:0042803	protein homodimerization activity
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P10599|THIO_HUMAN
Thioredoxin
Search

TXN

0.50	Thioredoxin

0.74	GO:0006662	glycerol ether metabolic process
0.67	GO:0045454	cell redox homeostasis
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0046822	regulation of nucleocytoplasmic transport
0.50	GO:0051223	regulation of protein transport
0.49	GO:0043388	positive regulation of DNA binding
0.48	GO:0051457	maintenance of protein location in nucleus
0.48	GO:1900180	regulation of protein localization to nucleus
0.47	GO:0032386	regulation of intracellular transport
0.47	GO:1904950	negative regulation of establishment of protein localization

0.71	GO:0015035	protein disulfide oxidoreductase activity
0.47	GO:0047134	protein-disulfide reductase activity
0.46	GO:0015037	peptide disulfide oxidoreductase activity
0.46	GO:0004791	thioredoxin-disulfide reductase activity
0.45	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.43	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0005576	extracellular region
0.40	GO:0005739	mitochondrion
0.36	GO:0031982	vesicle
0.35	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.34	GO:0097223	sperm part
0.33	GO:0005794	Golgi apparatus

0.47	EC:1.8.1.8	GO:0047134
0.46	KEGG:R02016	GO:0004791

sp|P10600|TGFB3_HUMAN
Transforming growth factor beta-3
Search

TGFB3

0.97	Transforming growth factor beta 3

0.80	GO:0016049	cell growth
0.74	GO:0010469	regulation of receptor activity
0.69	GO:0043932	ossification involved in bone remodeling
0.68	GO:0010936	negative regulation of macrophage cytokine production
0.67	GO:0032967	positive regulation of collagen biosynthetic process
0.67	GO:0032570	response to progesterone
0.66	GO:0070483	detection of hypoxia
0.66	GO:0060325	face morphogenesis
0.66	GO:0030501	positive regulation of bone mineralization
0.66	GO:0010718	positive regulation of epithelial to mesenchymal transition

0.85	GO:0005160	transforming growth factor beta receptor binding
0.77	GO:0008083	growth factor activity
0.67	GO:0050431	transforming growth factor beta binding
0.57	GO:0042802	identical protein binding
0.47	GO:0005125	cytokine activity
0.37	GO:0046982	protein heterodimerization activity

0.72	GO:0005615	extracellular space
0.58	GO:0031012	extracellular matrix
0.43	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0030315	T-tubule
0.38	GO:0043025	neuronal cell body
0.38	GO:0030141	secretory granule
0.37	GO:0009986	cell surface
0.36	GO:0060205	cytoplasmic vesicle lumen
0.30	GO:0016021	integral component of membrane

sp|P10606|COX5B_HUMAN
Cytochrome c oxidase subunit 5B, mitochondrial
Search

COX5B

0.85	Cytochrome c oxidase polypeptide Vb

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.47	GO:0006839	mitochondrial transport
0.45	GO:0006754	ATP biosynthetic process
0.44	GO:0046907	intracellular transport
0.43	GO:0006119	oxidative phosphorylation
0.43	GO:0009060	aerobic respiration
0.35	GO:0007585	respiratory gaseous exchange
0.35	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.35	GO:0043434	response to peptide hormone

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity
0.31	GO:0003677	DNA binding

0.62	GO:0044429	mitochondrial part
0.62	GO:0031967	organelle envelope
0.47	GO:0045277	respiratory chain complex IV
0.42	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0043209	myelin sheath
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P10619|PPGB_HUMAN
Lysosomal protective protein
Search

CTSA

0.57	Carboxypeptidase

0.60	GO:0006508	proteolysis
0.42	GO:0044257	cellular protein catabolic process
0.36	GO:1904715	negative regulation of chaperone-mediated autophagy
0.34	GO:0031647	regulation of protein stability
0.33	GO:0006368	transcription elongation from RNA polymerase II promoter

0.74	GO:0004185	serine-type carboxypeptidase activity
0.33	GO:0005515	protein binding

0.50	GO:0005654	nucleoplasm
0.38	GO:0005765	lysosomal membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005739	mitochondrion
0.32	GO:0043234	protein complex

0.74

EC:3.4.16

GO:0004185

sp|P10620|MGST1_HUMAN
Microsomal glutathione S-transferase 1
Search

MGST1

0.92	Microsomal glutathione S-transferase

0.63	GO:0071449	cellular response to lipid hydroperoxide
0.50	GO:0098869	cellular oxidant detoxification
0.44	GO:0070207	protein homotrimerization
0.42	GO:0055114	oxidation-reduction process
0.40	GO:0033327	Leydig cell differentiation
0.39	GO:0032496	response to lipopolysaccharide
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0042493	response to drug
0.37	GO:1901685	glutathione derivative metabolic process
0.36	GO:0006749	glutathione metabolic process

0.56	GO:0004364	glutathione transferase activity
0.55	GO:0004602	glutathione peroxidase activity
0.40	GO:0043295	glutathione binding
0.38	GO:0042803	protein homodimerization activity

0.46	GO:0005739	mitochondrion
0.40	GO:0031968	organelle outer membrane
0.40	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0045177	apical part of cell
0.38	GO:0031903	microbody membrane
0.38	GO:0044439	peroxisomal part
0.38	GO:0031984	organelle subcompartment
0.36	GO:0035577	azurophil granule membrane
0.35	GO:0005634	nucleus

0.56

GO:0004364

sp|P10632|CP2C8_HUMAN
Cytochrome P450 2C8
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.57	GO:0042738	exogenous drug catabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0002933	lipid hydroxylation
0.50	GO:0008202	steroid metabolic process
0.50	GO:0070988	demethylation
0.48	GO:0016098	monoterpenoid metabolic process
0.43	GO:0019373	epoxygenase P450 pathway
0.39	GO:0019627	urea metabolic process
0.34	GO:0046483	heterocycle metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.55	GO:0034875	caffeine oxidase activity
0.38	GO:0019899	enzyme binding
0.35	GO:0008144	drug binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P10635|CP2D6_HUMAN
Cytochrome P450 2D6
Search

CYP2D6

0.97	Debrisoquine 4-hydroxylase mutant allele (CYP2D6-MA1)

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0019369	arachidonic acid metabolic process
0.38	GO:0090349	negative regulation of cellular organohalogen metabolic process
0.38	GO:0090348	regulation of cellular organofluorine metabolic process
0.38	GO:0008202	steroid metabolic process
0.37	GO:0009822	alkaloid catabolic process
0.37	GO:0033076	isoquinoline alkaloid metabolic process
0.37	GO:0009804	coumarin metabolic process
0.37	GO:0042738	exogenous drug catabolic process
0.37	GO:0016098	monoterpenoid metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0008395	steroid hydroxylase activity
0.35	GO:0008391	arachidonic acid monooxygenase activity
0.34	GO:0019825	oxygen binding

0.40	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P10636|TAU_HUMAN
Microtubule-associated protein tau
Search

MAPT

0.74	Microtubule-associated protein tau

0.81	GO:0045773	positive regulation of axon extension
0.80	GO:0031116	positive regulation of microtubule polymerization
0.72	GO:0000226	microtubule cytoskeleton organization
0.67	GO:0090258	negative regulation of mitochondrial fission
0.66	GO:1902474	positive regulation of protein localization to synapse
0.66	GO:0010917	negative regulation of mitochondrial membrane potential
0.65	GO:1903748	negative regulation of establishment of protein localization to mitochondrion
0.65	GO:1990000	amyloid fibril formation
0.64	GO:0032930	positive regulation of superoxide anion generation
0.64	GO:0047497	mitochondrion transport along microtubule

0.74	GO:0008017	microtubule binding
0.65	GO:0034185	apolipoprotein binding
0.64	GO:0071813	lipoprotein particle binding
0.59	GO:0017124	SH3 domain binding
0.56	GO:0051879	Hsp90 protein binding
0.56	GO:0048018	receptor ligand activity
0.56	GO:0051721	protein phosphatase 2A binding
0.56	GO:0042803	protein homodimerization activity
0.55	GO:0099077	histone-dependent DNA binding
0.52	GO:0019901	protein kinase binding

0.84	GO:0045298	tubulin complex
0.79	GO:0030424	axon
0.78	GO:0030426	growth cone
0.72	GO:0005874	microtubule
0.68	GO:0005829	cytosol
0.65	GO:0097418	neurofibrillary tangle
0.62	GO:0032589	neuron projection membrane
0.62	GO:0005875	microtubule associated complex
0.59	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.59	GO:0034399	nuclear periphery

sp|P10643|CO7_HUMAN
Complement component C7
Search

0.97	Complement component 7

0.84	GO:0006956	complement activation
0.41	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.40	GO:0045087	innate immune response
0.39	GO:0019835	cytolysis
0.39	GO:0006883	cellular sodium ion homeostasis
0.36	GO:0030449	regulation of complement activation
0.34	GO:0042981	regulation of apoptotic process
0.33	GO:0006030	chitin metabolic process

0.33	GO:0005198	structural molecule activity
0.33	GO:0008061	chitin binding

0.85	GO:0005579	membrane attack complex
0.38	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.34	GO:0019028	viral capsid

sp|P10644|KAP0_HUMAN
cAMP-dependent protein kinase type I-alpha regulatory subunit
Search

PRKAR1A

0.97	cAMP-dependent protein kinase type I-alpha regulatory subunit

0.74	GO:0045859	regulation of protein kinase activity
0.57	GO:0046007	negative regulation of activated T cell proliferation
0.56	GO:0060038	cardiac muscle cell proliferation
0.55	GO:0033673	negative regulation of kinase activity
0.54	GO:0045214	sarcomere organization
0.54	GO:0001707	mesoderm formation
0.52	GO:0001933	negative regulation of protein phosphorylation
0.51	GO:0016310	phosphorylation
0.41	GO:0007611	learning or memory
0.40	GO:0051445	regulation of meiotic cell cycle

0.84	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.59	GO:0034236	protein kinase A catalytic subunit binding
0.58	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.52	GO:0016301	kinase activity
0.52	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0019904	protein domain specific binding
0.34	GO:0042802	identical protein binding
0.33	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.56	GO:0001772	immunological synapse
0.55	GO:0031588	nucleotide-activated protein kinase complex
0.54	GO:0044853	plasma membrane raft
0.54	GO:0031594	neuromuscular junction
0.53	GO:0005930	axoneme
0.35	GO:0097546	ciliary base
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.32

GO:0016773

sp|P10645|CMGA_HUMAN
Chromogranin-A
Search

CHGA

0.97	Chromogranin-A

0.69	GO:2000707	positive regulation of dense core granule biogenesis
0.68	GO:0032762	mast cell cytokine production
0.68	GO:0002551	mast cell chemotaxis
0.67	GO:0033604	negative regulation of catecholamine secretion
0.66	GO:0002279	mast cell activation involved in immune response
0.65	GO:0002448	mast cell mediated immunity
0.64	GO:0043299	leukocyte degranulation
0.64	GO:0032418	lysosome localization
0.62	GO:0050830	defense response to Gram-positive bacterium
0.62	GO:0050829	defense response to Gram-negative bacterium

0.35	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.32	GO:0004871	signal transducer activity
0.31	GO:0005198	structural molecule activity

0.81	GO:0030141	secretory granule
0.65	GO:0042629	mast cell granule
0.58	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0030658	transport vesicle membrane
0.40	GO:0005576	extracellular region
0.32	GO:0005883	neurofilament
0.30	GO:0016021	integral component of membrane

sp|P10646|TFPI1_HUMAN
Tissue factor pathway inhibitor
Search

TFPI

0.82	Tissue factor pathway inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.67	GO:0007596	blood coagulation
0.59	GO:0030195	negative regulation of blood coagulation
0.55	GO:0071383	cellular response to steroid hormone stimulus
0.39	GO:0032355	response to estradiol
0.39	GO:0071347	cellular response to interleukin-1
0.38	GO:0071222	cellular response to lipopolysaccharide
0.37	GO:0072376	protein activation cascade
0.34	GO:0006508	proteolysis
0.34	GO:0006030	chitin metabolic process

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0008233	peptidase activity
0.34	GO:0008061	chitin binding

0.64	GO:0005576	extracellular region
0.57	GO:0005901	caveola
0.53	GO:0009986	cell surface
0.36	GO:0031225	anchored component of membrane
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0008233

sp|P10696|PPBN_HUMAN
Alkaline phosphatase, placental-like
Search

0.47	Intestinal-type alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.46	GO:0001958	endochondral ossification
0.45	GO:0033280	response to vitamin D
0.44	GO:0071310	cellular response to organic substance
0.42	GO:0003006	developmental process involved in reproduction
0.42	GO:0046677	response to antibiotic
0.40	GO:0071772	response to BMP
0.38	GO:0071495	cellular response to endogenous stimulus
0.38	GO:0006501	C-terminal protein lipidation
0.37	GO:0031214	biomineral tissue development

0.80	GO:0004035	alkaline phosphatase activity
0.45	GO:0002020	protease binding
0.39	GO:0000287	magnesium ion binding
0.38	GO:0008270	zinc ion binding
0.38	GO:0016462	pyrophosphatase activity
0.34	GO:0042803	protein homodimerization activity

0.47	GO:0065010	extracellular membrane-bounded organelle
0.44	GO:0031225	anchored component of membrane
0.43	GO:0005886	plasma membrane
0.42	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0009986	cell surface
0.38	GO:0098552	side of membrane
0.37	GO:0030016	myofibril
0.35	GO:0005903	brush border
0.34	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle

0.80

GO:0004035

sp|P10720|PF4V_HUMAN
Platelet factor 4 variant
Search

0.79	C-X-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.81	GO:0030168	platelet activation
0.80	GO:0050900	leukocyte migration
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.72	GO:0006952	defense response
0.57	GO:0001562	response to protozoan
0.54	GO:0019221	cytokine-mediated signaling pathway
0.52	GO:0045347	negative regulation of MHC class II biosynthetic process
0.52	GO:0042127	regulation of cell proliferation

0.84	GO:0008009	chemokine activity
0.79	GO:0008201	heparin binding
0.58	GO:0045236	CXCR chemokine receptor binding

0.73	GO:0005615	extracellular space
0.53	GO:0097679	other organism cytoplasm
0.52	GO:0020005	symbiont-containing vacuole membrane
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P10721|KIT_HUMAN
Mast/stem cell growth factor receptor Kit
Search

KIT

0.68	KIT proto-oncogene receptor tyrosine kinase

0.86	GO:0038109	Kit signaling pathway
0.85	GO:0038093	Fc receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0023014	signal transduction by protein phosphorylation
0.64	GO:0097326	melanocyte adhesion
0.64	GO:0002371	dendritic cell cytokine production
0.63	GO:0060374	mast cell differentiation
0.62	GO:0038162	erythropoietin-mediated signaling pathway
0.62	GO:0032762	mast cell cytokine production
0.62	GO:0097324	melanocyte migration

0.85	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.82	GO:0019955	cytokine binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.57	GO:0002020	protease binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.53	GO:0046872	metal ion binding
0.52	GO:0042803	protein homodimerization activity

0.60	GO:0042629	mast cell granule
0.56	GO:0009897	external side of plasma membrane
0.53	GO:0005911	cell-cell junction
0.51	GO:0005615	extracellular space
0.41	GO:0001669	acrosomal vesicle
0.39	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.10	GO:0004716
0.36	KEGG:R04545	GO:0046934

sp|P10745|RET3_HUMAN
Retinol-binding protein 3
Search

RBP3

0.61	Retinol-binding protein 3

0.78	GO:0007601	visual perception
0.61	GO:0006508	proteolysis
0.30	GO:0001523	retinoid metabolic process

0.83	GO:0005501	retinoid binding
0.67	GO:0008236	serine-type peptidase activity
0.64	GO:0043178	alcohol binding
0.52	GO:0019842	vitamin binding

0.84	GO:0033165	interphotoreceptor matrix
0.63	GO:0044420	extracellular matrix component
0.42	GO:0005737	cytoplasm
0.30	GO:0043230	extracellular organelle
0.30	GO:0005615	extracellular space
0.30	GO:0031982	vesicle

sp|P10746|HEM4_HUMAN
Uroporphyrinogen-III synthase
Search

UROS

0.48	Uroporphyrinogen-III synthase

0.69	GO:0033014	tetrapyrrole biosynthetic process
0.63	GO:0046502	uroporphyrinogen III metabolic process
0.52	GO:0042168	heme metabolic process
0.51	GO:0046148	pigment biosynthetic process
0.47	GO:0051188	cofactor biosynthetic process
0.46	GO:0046394	carboxylic acid biosynthetic process
0.44	GO:0070541	response to platinum ion
0.43	GO:0071418	cellular response to amine stimulus
0.42	GO:0071243	cellular response to arsenic-containing substance
0.39	GO:0046677	response to antibiotic

0.79	GO:0004852	uroporphyrinogen-III synthase activity
0.35	GO:0048037	cofactor binding

0.45	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79	EC:4.2.1.75	GO:0004852
0.79	KEGG:R03165	GO:0004852

sp|P10747|CD28_HUMAN
T-cell-specific surface glycoprotein CD28
Search

CD28

0.96	T-cell-specific surface glycoprotein CD28

0.73	GO:0006955	immune response
0.68	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.64	GO:0042102	positive regulation of T cell proliferation
0.64	GO:0045840	positive regulation of mitotic nuclear division
0.62	GO:0032753	positive regulation of interleukin-4 production
0.62	GO:0045066	regulatory T cell differentiation
0.61	GO:0032733	positive regulation of interleukin-10 production
0.60	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.60	GO:0002863	positive regulation of inflammatory response to antigenic stimulus
0.60	GO:0045060	negative thymic T cell selection

0.58	GO:0005070	SH3/SH2 adaptor activity
0.57	GO:0002020	protease binding
0.54	GO:0019901	protein kinase binding
0.39	GO:0015026	coreceptor activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0042802	identical protein binding
0.34	GO:0046983	protein dimerization activity

0.58	GO:0001772	immunological synapse
0.56	GO:0009897	external side of plasma membrane
0.56	GO:0098636	protein complex involved in cell adhesion
0.40	GO:0044214	spanning component of plasma membrane
0.35	GO:0045121	membrane raft
0.35	GO:0005829	cytosol

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|P10767|FGF6_HUMAN
Fibroblast growth factor 6
Search

FGF6

0.62	Fibroblast growth factor

0.76	GO:0010469	regulation of receptor activity
0.75	GO:0008543	fibroblast growth factor receptor signaling pathway
0.59	GO:0001502	cartilage condensation
0.56	GO:0045445	myoblast differentiation
0.55	GO:0008284	positive regulation of cell proliferation
0.45	GO:0060591	chondroblast differentiation
0.45	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.44	GO:0010463	mesenchymal cell proliferation
0.43	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.43	GO:0060363	cranial suture morphogenesis

0.78	GO:0008083	growth factor activity
0.76	GO:0005104	fibroblast growth factor receptor binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.60	GO:0005576	extracellular region
0.38	GO:0042383	sarcolemma
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P10768|ESTD_HUMAN
S-formylglutathione hydrolase
Search

ESD

0.61	S-formylglutathione hydrolase

0.80	GO:0046294	formaldehyde catabolic process
0.36	GO:1901687	glutathione derivative biosynthetic process
0.34	GO:0007276	gamete generation

0.81	GO:0018738	S-formylglutathione hydrolase activity
0.69	GO:0052689	carboxylic ester hydrolase activity
0.48	GO:0042802	identical protein binding
0.34	GO:0019213	deacetylase activity

0.48	GO:0005737	cytoplasm
0.38	GO:0097708	intracellular vesicle
0.36	GO:0070062	extracellular exosome
0.34	GO:0012505	endomembrane system
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.81	EC:3.1.2.12	GO:0018738
0.81	KEGG:R00527	GO:0018738

sp|P10809|CH60_HUMAN
60 kDa heat shock protein, mitochondrial
Search

HSPD1

0.79	Heat shock protein, mitochondrial

0.76	GO:0042026	protein refolding
0.64	GO:0009409	response to cold
0.53	GO:0042110	T cell activation
0.53	GO:0002368	B cell cytokine production
0.53	GO:0048291	isotype switching to IgG isotypes
0.52	GO:0002842	positive regulation of T cell mediated immune response to tumor cell
0.52	GO:0001817	regulation of cytokine production
0.50	GO:0043032	positive regulation of macrophage activation
0.50	GO:0042100	B cell proliferation
0.49	GO:0045041	protein import into mitochondrial intermembrane space

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0034186	apolipoprotein A-I binding
0.51	GO:0008035	high-density lipoprotein particle binding
0.49	GO:0002039	p53 binding
0.49	GO:0044183	protein binding involved in protein folding
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0051087	chaperone binding

0.50	GO:0005759	mitochondrial matrix
0.50	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.49	GO:0046696	lipopolysaccharide receptor complex
0.48	GO:0043209	myelin sheath
0.48	GO:0030141	secretory granule
0.47	GO:0070062	extracellular exosome
0.47	GO:0005905	clathrin-coated pit
0.47	GO:0005769	early endosome
0.46	GO:0005829	cytosol
0.46	GO:0030135	coated vesicle

0.35

GO:0016787

sp|P10826|RARB_HUMAN
Retinoic acid receptor beta
Search

RARB

0.91	Retinoic acid receptor alpha

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0003417	growth plate cartilage development
0.58	GO:0061037	negative regulation of cartilage development
0.58	GO:0002068	glandular epithelial cell development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0055012	ventricular cardiac muscle cell differentiation
0.57	GO:0003148	outflow tract septum morphogenesis
0.57	GO:0003406	retinal pigment epithelium development
0.57	GO:2001141	regulation of RNA biosynthetic process

0.85	GO:0003708	retinoic acid receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.43	GO:0046965	retinoid X receptor binding
0.41	GO:0043422	protein kinase B binding
0.41	GO:0001972	retinoic acid binding
0.40	GO:0051393	alpha-actinin binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.38	GO:0005694	chromosome
0.38	GO:0015629	actin cytoskeleton
0.37	GO:0005829	cytosol
0.35	GO:0005667	transcription factor complex
0.35	GO:0048471	perinuclear region of cytoplasm

sp|P10827|THA_HUMAN
Thyroid hormone receptor alpha
Search

THRA

0.93	Thyroid hormone receptor alpha variant a

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0008050	female courtship behavior
0.55	GO:0045925	positive regulation of female receptivity
0.54	GO:0060509	Type I pneumocyte differentiation
0.54	GO:0002155	regulation of thyroid hormone mediated signaling pathway

0.85	GO:0004887	thyroid hormone receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.58	GO:0070324	thyroid hormone binding
0.56	GO:0002153	steroid receptor RNA activator RNA binding
0.51	GO:0031490	chromatin DNA binding
0.50	GO:0017025	TBP-class protein binding
0.48	GO:0019904	protein domain specific binding
0.48	GO:0044212	transcription regulatory region DNA binding

0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.33	GO:0005694	chromosome
0.30	GO:0044425	membrane part

sp|P10828|THB_HUMAN
Thyroid hormone receptor beta
Search

THRB

0.94	Thyroid hormone receptor beta

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0008050	female courtship behavior
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060509	Type I pneumocyte differentiation
0.55	GO:0007621	negative regulation of female receptivity
0.52	GO:0008016	regulation of heart contraction

0.85	GO:0004887	thyroid hormone receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.57	GO:0070324	thyroid hormone binding
0.52	GO:0031490	chromatin DNA binding
0.46	GO:0019899	enzyme binding
0.37	GO:0000989	transcription factor activity, transcription factor binding
0.36	GO:0003690	double-stranded DNA binding
0.35	GO:0046983	protein dimerization activity

0.61	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.45	GO:0043233	organelle lumen
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P10909|CLUS_HUMAN
Clusterin
Search

CLU

0.96

Clusterin

0.76	GO:1902847	regulation of neuronal signal transduction
0.76	GO:1905895	negative regulation of cellular response to tunicamycin
0.76	GO:1905892	negative regulation of cellular response to thapsigargin
0.76	GO:1902998	positive regulation of neurofibrillary tangle assembly
0.75	GO:0032463	negative regulation of protein homooligomerization
0.75	GO:0061518	microglial cell proliferation
0.75	GO:1902949	positive regulation of tau-protein kinase activity
0.74	GO:1905907	negative regulation of amyloid fibril formation
0.74	GO:0032286	central nervous system myelin maintenance
0.73	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.73	GO:0051787	misfolded protein binding
0.71	GO:0050750	low-density lipoprotein particle receptor binding
0.69	GO:0001540	amyloid-beta binding
0.66	GO:0031625	ubiquitin protein ligase binding
0.61	GO:0032403	protein complex binding
0.42	GO:0016887	ATPase activity
0.40	GO:0051087	chaperone binding
0.38	GO:0047485	protein N-terminus binding
0.37	GO:0097099	structural constituent of albumen

0.75	GO:0034366	spherical high-density lipoprotein particle
0.73	GO:0097418	neurofibrillary tangle
0.72	GO:0097440	apical dendrite
0.71	GO:0106003	amyloid-beta complex
0.66	GO:0048471	perinuclear region of cytoplasm
0.63	GO:0031012	extracellular matrix
0.62	GO:0009986	cell surface
0.55	GO:0042583	chromaffin granule
0.53	GO:0005739	mitochondrion
0.47	GO:0071944	cell periphery

0.42

GO:0016887

sp|P10911|MCF2_HUMAN
Proto-oncogene DBL
Search

MCF2

0.96	LOW QUALITY PROTEIN: proto-oncogene DBL

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.42	GO:1990823	response to leukemia inhibitory factor
0.42	GO:0016358	dendrite development
0.41	GO:0071345	cellular response to cytokine stimulus
0.36	GO:0050771	negative regulation of axonogenesis
0.35	GO:0043065	positive regulation of apoptotic process
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.78

GO:0005089

Rho guanyl-nucleotide exchange factor activity

0.45	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P10912|GHR_HUMAN
Growth hormone receptor
Search

GHR

0.63	Liver growth hormone receptor

0.79	GO:0019221	cytokine-mediated signaling pathway
0.47	GO:0006897	endocytosis
0.47	GO:0060396	growth hormone receptor signaling pathway
0.44	GO:0042976	activation of Janus kinase activity
0.43	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.42	GO:0007259	JAK-STAT cascade
0.42	GO:0000187	activation of MAPK activity
0.42	GO:0009410	response to xenobiotic stimulus
0.41	GO:0051094	positive regulation of developmental process
0.41	GO:0033993	response to lipid

0.81	GO:0004896	cytokine receptor activity
0.42	GO:0017046	peptide hormone binding
0.41	GO:0042169	SH2 domain binding
0.41	GO:0019901	protein kinase binding
0.40	GO:0019903	protein phosphatase binding
0.40	GO:0070064	proline-rich region binding
0.40	GO:0019838	growth factor binding
0.39	GO:0042803	protein homodimerization activity

0.55	GO:0036464	cytoplasmic ribonucleoprotein granule
0.50	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane
0.46	GO:0005576	extracellular region
0.43	GO:0070195	growth hormone receptor complex
0.40	GO:0043025	neuronal cell body
0.39	GO:0009986	cell surface
0.37	GO:0031904	endosome lumen
0.37	GO:0005634	nucleus
0.37	GO:0019898	extrinsic component of membrane

sp|P10914|IRF1_HUMAN
Interferon regulatory factor 1
Search

IRF1

0.92	Interferon regulatory factor

0.78	GO:0008285	negative regulation of cell proliferation
0.77	GO:0006915	apoptotic process
0.71	GO:0050776	regulation of immune response
0.66	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation
0.66	GO:0045590	negative regulation of regulatory T cell differentiation
0.65	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.64	GO:0035458	cellular response to interferon-beta
0.64	GO:0043374	CD8-positive, alpha-beta T cell differentiation
0.64	GO:0032728	positive regulation of interferon-beta production
0.64	GO:0060333	interferon-gamma-mediated signaling pathway

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:1990837	sequence-specific double-stranded DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0030545	receptor regulator activity

0.61	GO:0005634	nucleus
0.54	GO:0000785	chromatin
0.52	GO:0070013	intracellular organelle lumen
0.41	GO:0005737	cytoplasm
0.36	GO:0005925	focal adhesion
0.33	GO:0005576	extracellular region

sp|P10915|HPLN1_HUMAN
Hyaluronan and proteoglycan link protein 1
Search

HAPLN1

0.97	Hyaluronan and proteoglycan link protein 1

0.71	GO:0007155	cell adhesion
0.48	GO:0001501	skeletal system development
0.47	GO:0007417	central nervous system development
0.40	GO:0031101	fin regeneration
0.35	GO:0030198	extracellular matrix organization
0.35	GO:0002040	sprouting angiogenesis

0.83	GO:0005540	hyaluronic acid binding
0.48	GO:0005201	extracellular matrix structural constituent

0.53	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|P10916|MLRV_HUMAN
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
Search

MYL2

0.96	Cardiac ventricular myosin light chain-2

0.59	GO:0098735	positive regulation of the force of heart contraction
0.58	GO:0042694	muscle cell fate specification
0.57	GO:0055003	cardiac myofibril assembly
0.56	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.56	GO:0060047	heart contraction
0.55	GO:0048747	muscle fiber development
0.55	GO:0006941	striated muscle contraction
0.54	GO:0030308	negative regulation of cell growth
0.52	GO:0009791	post-embryonic development
0.36	GO:0061049	cell growth involved in cardiac muscle cell development

0.69	GO:0005509	calcium ion binding
0.55	GO:0003785	actin monomer binding
0.35	GO:0032036	myosin heavy chain binding
0.35	GO:0008307	structural constituent of muscle

0.57	GO:0097512	cardiac myofibril
0.51	GO:0015629	actin cytoskeleton
0.40	GO:0031672	A band
0.38	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.35	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P10966|CD8B_HUMAN
T-cell surface glycoprotein CD8 beta chain
Search

CD8B

0.94	T-cell surface glycoprotein CD8 beta chain

0.47	GO:0002250	adaptive immune response
0.39	GO:0042110	T cell activation
0.38	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.37	GO:0050776	regulation of immune response
0.37	GO:0050690	regulation of defense response to virus by virus

0.40	GO:0042288	MHC class I protein binding
0.39	GO:0015026	coreceptor activity
0.32	GO:0099600	transmembrane receptor activity

0.42	GO:0009897	external side of plasma membrane
0.39	GO:0042101	T cell receptor complex
0.39	GO:0031901	early endosome membrane
0.36	GO:0005887	integral component of plasma membrane
0.36	GO:0005576	extracellular region

sp|P10997|IAPP_HUMAN
Islet amyloid polypeptide
Search

IAPP

0.94	islet amyloid polypeptide precursor

0.76	GO:0010469	regulation of receptor activity
0.66	GO:0045779	negative regulation of bone resorption
0.63	GO:0019233	sensory perception of pain
0.59	GO:0045596	negative regulation of cell differentiation
0.46	GO:0097647	amylin receptor signaling pathway
0.45	GO:0042755	eating behavior
0.41	GO:0030816	positive regulation of cAMP metabolic process
0.39	GO:1905907	negative regulation of amyloid fibril formation
0.39	GO:1900019	regulation of protein kinase C activity
0.39	GO:1990000	amyloid fibril formation

0.79	GO:0005179	hormone activity
0.55	GO:0042802	identical protein binding
0.38	GO:0001540	amyloid-beta binding

0.66	GO:0005576	extracellular region
0.60	GO:0043025	neuronal cell body
0.38	GO:0016234	inclusion body
0.36	GO:0030141	secretory granule
0.35	GO:0005829	cytosol

sp|P11021|GRP78_HUMAN
78 kDa glucose-regulated protein
Search

HSPA5

0.73	Glucose-regulated protein 78

0.54	GO:1903895	negative regulation of IRE1-mediated unfolded protein response
0.54	GO:0090074	negative regulation of protein homodimerization activity
0.50	GO:0035437	maintenance of protein localization in endoplasmic reticulum
0.49	GO:0030335	positive regulation of cell migration
0.49	GO:0021589	cerebellum structural organization
0.48	GO:0006987	activation of signaling protein activity involved in unfolded protein response
0.48	GO:0006983	ER overload response
0.47	GO:0071353	cellular response to interleukin-4
0.47	GO:0021680	cerebellar Purkinje cell layer development
0.46	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.47	GO:0051787	misfolded protein binding
0.45	GO:0045296	cadherin binding
0.45	GO:0019904	protein domain specific binding
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0016887	ATPase activity
0.43	GO:0043022	ribosome binding

0.53	GO:0005788	endoplasmic reticulum lumen
0.48	GO:0042470	melanosome
0.48	GO:0034663	endoplasmic reticulum chaperone complex
0.46	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.45	GO:0030496	midbody
0.45	GO:0043209	myelin sheath
0.45	GO:0030176	integral component of endoplasmic reticulum membrane
0.45	GO:0008180	COP9 signalosome
0.43	GO:0009986	cell surface
0.42	GO:0005790	smooth endoplasmic reticulum

0.43

GO:0016887

sp|P11047|LAMC1_HUMAN
Laminin subunit gamma-1
Search

LAMC1

0.71	Laminin subunit gamma-1

0.84	GO:0031581	hemidesmosome assembly
0.84	GO:0022617	extracellular matrix disassembly
0.81	GO:0034446	substrate adhesion-dependent cell spreading
0.73	GO:0016477	cell migration
0.65	GO:0006461	protein complex assembly
0.49	GO:0009888	tissue development
0.47	GO:0050679	positive regulation of epithelial cell proliferation
0.47	GO:0007634	optokinetic behavior
0.47	GO:0048570	notochord morphogenesis
0.46	GO:0043687	post-translational protein modification

0.77	GO:0005201	extracellular matrix structural constituent
0.41	GO:0043208	glycosphingolipid binding
0.40	GO:0004871	signal transducer activity
0.38	GO:0005509	calcium ion binding
0.32	GO:0005515	protein binding

0.79	GO:0005604	basement membrane
0.48	GO:0070062	extracellular exosome
0.47	GO:0005788	endoplasmic reticulum lumen
0.41	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P11049|CD37_HUMAN
Leukocyte antigen CD37
Search

CD37

0.59	Tetraspanin

0.44

GO:0007166

cell surface receptor signaling pathway

0.59	GO:0001772	immunological synapse
0.42	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus

sp|P11055|MYH3_HUMAN
Myosin-3
Search

0.83	Developmental myosin heavy chain embryonic

0.74	GO:0007018	microtubule-based movement
0.59	GO:0006936	muscle contraction
0.58	GO:0050881	musculoskeletal movement
0.52	GO:0070252	actin-mediated cell contraction
0.46	GO:0046034	ATP metabolic process
0.44	GO:0014823	response to activity
0.40	GO:0001778	plasma membrane repair
0.36	GO:0030036	actin cytoskeleton organization
0.35	GO:0060325	face morphogenesis
0.35	GO:0097435	supramolecular fiber organization

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.60	GO:0000146	microfilament motor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0016887	ATPase activity
0.43	GO:0005516	calmodulin binding
0.37	GO:0017018	myosin phosphatase activity

0.77	GO:0016459	myosin complex
0.57	GO:0043292	contractile fiber
0.43	GO:0014704	intercalated disc
0.40	GO:0036464	cytoplasmic ribonucleoprotein granule
0.39	GO:0005826	actomyosin contractile ring
0.37	GO:0005794	Golgi apparatus
0.36	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.45

GO:0016887

sp|P11086|PNMT_HUMAN
Phenylethanolamine N-methyltransferase
Search

PNMT

0.94	Phenylethanolamine N-methyltransferase

0.63	GO:0032259	methylation
0.45	GO:0042418	epinephrine biosynthetic process
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0031100	animal organ regeneration
0.37	GO:0035900	response to isolation stress
0.37	GO:0042493	response to drug
0.36	GO:0035902	response to immobilization stress
0.36	GO:0045472	response to ether
0.36	GO:0042415	norepinephrine metabolic process
0.36	GO:0009636	response to toxic substance

0.63	GO:0008168	methyltransferase activity
0.32	GO:0005515	protein binding

0.44	GO:0005829	cytosol
0.37	GO:0043196	varicosity
0.36	GO:0043204	perikaryon
0.36	GO:0043195	terminal bouton
0.35	GO:0030425	dendrite
0.33	GO:0005634	nucleus

0.63

GO:0008168

sp|P11117|PPAL_HUMAN
Lysosomal acid phosphatase
Search

ACP2

0.84	Lysosomal acid phosphatase

0.57	GO:0007040	lysosome organization
0.55	GO:0001501	skeletal system development
0.49	GO:0016311	dephosphorylation
0.36	GO:0048102	autophagic cell death
0.35	GO:0042476	odontogenesis
0.34	GO:0007268	chemical synaptic transmission
0.34	GO:0010033	response to organic substance
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.54	GO:0003993	acid phosphatase activity
0.35	GO:0001784	phosphotyrosine residue binding
0.34	GO:0004721	phosphoprotein phosphatase activity

0.55	GO:0005764	lysosome
0.43	GO:0005775	vacuolar lumen
0.41	GO:0098852	lytic vacuole membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0043005	neuron projection
0.34	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

0.54

EC:3.1.3.2

GO:0003993

sp|P11137|MTAP2_HUMAN
Microtubule-associated protein 2
Search

MAP2

0.61	Microtubule-associated protein (Fragment)

0.85	GO:0021954	central nervous system neuron development
0.83	GO:0001578	microtubule bundle formation
0.62	GO:0016358	dendrite development
0.60	GO:0050770	regulation of axonogenesis
0.60	GO:0048667	cell morphogenesis involved in neuron differentiation
0.60	GO:0048812	neuron projection morphogenesis
0.59	GO:0030010	establishment of cell polarity
0.58	GO:0061564	axon development
0.54	GO:0071310	cellular response to organic substance

0.73	GO:0015631	tubulin binding
0.64	GO:0002162	dystroglycan binding

0.73	GO:0005874	microtubule
0.65	GO:0097442	CA3 pyramidal cell dendrite
0.62	GO:0043198	dendritic shaft
0.60	GO:0014069	postsynaptic density
0.59	GO:0034399	nuclear periphery
0.59	GO:0043025	neuronal cell body
0.56	GO:0005730	nucleolus
0.53	GO:0005829	cytosol
0.44	GO:0005875	microtubule associated complex

sp|P11142|HSP7C_HUMAN
Heat shock cognate 71 kDa protein
Search

HSPA8

0.75	Heat shock cognate protein isoform A

0.56	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy
0.55	GO:0061738	late endosomal microautophagy
0.54	GO:0072318	clathrin coat disassembly
0.54	GO:0044829	positive regulation by host of viral genome replication
0.53	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.51	GO:0051085	chaperone cofactor-dependent protein refolding
0.50	GO:1902904	negative regulation of supramolecular fiber organization
0.50	GO:0031647	regulation of protein stability
0.49	GO:0042026	protein refolding
0.48	GO:0045892	negative regulation of transcription, DNA-templated

0.56	GO:0055131	C3HC4-type RING finger domain binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0001786	phosphatidylserine binding
0.51	GO:0045296	cadherin binding
0.50	GO:0001664	G-protein coupled receptor binding
0.50	GO:0031072	heat shock protein binding
0.50	GO:0031625	ubiquitin protein ligase binding

0.53	GO:0000974	Prp19 complex
0.51	GO:0070062	extracellular exosome
0.51	GO:0043209	myelin sheath
0.50	GO:0005770	late endosome
0.49	GO:0000151	ubiquitin ligase complex
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0042470	melanosome
0.38	GO:0043202	lysosomal lumen

sp|P11150|LIPC_HUMAN
Hepatic triacylglycerol lipase
Search

LIPC

0.97	Hepatic triacylglycerol lipase

0.62	GO:0006629	lipid metabolic process
0.55	GO:0034372	very-low-density lipoprotein particle remodeling
0.55	GO:0034374	low-density lipoprotein particle remodeling
0.55	GO:0034375	high-density lipoprotein particle remodeling
0.53	GO:0070328	triglyceride homeostasis
0.53	GO:0042632	cholesterol homeostasis
0.52	GO:0030301	cholesterol transport
0.50	GO:1902652	secondary alcohol metabolic process
0.46	GO:0072330	monocarboxylic acid biosynthetic process
0.44	GO:0044248	cellular catabolic process

0.78	GO:0004806	triglyceride lipase activity
0.40	GO:0008201	heparin binding
0.38	GO:0034185	apolipoprotein binding
0.38	GO:0030169	low-density lipoprotein particle binding
0.36	GO:0004620	phospholipase activity
0.36	GO:0035478	chylomicron binding
0.35	GO:0043395	heparan sulfate proteoglycan binding
0.35	GO:0047372	acylglycerol lipase activity
0.34	GO:0008289	lipid binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.65	GO:0005576	extracellular region
0.41	GO:1990777	lipoprotein particle
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005902	microvillus
0.35	GO:0005770	late endosome
0.35	GO:0005769	early endosome
0.34	GO:0009986	cell surface

0.78

EC:3.1.1.3

GO:0004806

sp|P11161|EGR2_HUMAN
E3 SUMO-protein ligase EGR2
Search

EGR2

0.97	Early growth response protein 2

0.61	GO:0021666	rhombomere 5 formation
0.61	GO:0021660	rhombomere 3 formation
0.60	GO:0035283	central nervous system segmentation
0.59	GO:0021612	facial nerve structural organization
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0014037	Schwann cell differentiation
0.57	GO:0007622	rhythmic behavior
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006611	protein export from nucleus

0.56	GO:0001102	RNA polymerase II activating transcription factor binding
0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0046872	metal ion binding
0.52	GO:0003682	chromatin binding
0.42	GO:0016874	ligase activity
0.42	GO:0071837	HMG box domain binding

0.61	GO:0005634	nucleus
0.48	GO:0043233	organelle lumen
0.44	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm

0.42

GO:0016874

sp|P11166|GTR1_HUMAN
Solute carrier family 2, facilitated glucose transporter member 1
Search

SLC2A1

0.87	Solute carrier family 2, facilitated glucose transporter member 1

0.73	GO:1904659	glucose transmembrane transport
0.54	GO:0070837	dehydroascorbic acid transport
0.51	GO:0032868	response to insulin
0.51	GO:0071548	response to dexamethasone
0.51	GO:0042149	cellular response to glucose starvation
0.47	GO:0006461	protein complex assembly
0.41	GO:0002040	sprouting angiogenesis
0.40	GO:1904016	response to Thyroglobulin triiodothyronine
0.39	GO:0071260	cellular response to mechanical stimulus
0.39	GO:0071474	cellular hyperosmotic response

0.73	GO:0005355	glucose transmembrane transporter activity
0.54	GO:0043621	protein self-association
0.54	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.48	GO:0042802	identical protein binding
0.38	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0019900	kinase binding

0.54	GO:0001939	female pronucleus
0.52	GO:0030864	cortical actin cytoskeleton
0.52	GO:0030496	midbody
0.50	GO:0016323	basolateral plasma membrane
0.50	GO:0016324	apical plasma membrane
0.50	GO:0045121	membrane raft
0.47	GO:0031982	vesicle
0.46	GO:0005887	integral component of plasma membrane
0.45	GO:0005829	cytosol
0.39	GO:0014704	intercalated disc

sp|P11168|GTR2_HUMAN
Solute carrier family 2, facilitated glucose transporter member 2
Search

SLC2A2

0.95	Faciliated glucose transporter 2

0.70	GO:1904659	glucose transmembrane transport
0.63	GO:0070837	dehydroascorbic acid transport
0.48	GO:0046323	glucose import
0.46	GO:0043434	response to peptide hormone
0.45	GO:1901653	cellular response to peptide
0.44	GO:0001889	liver development
0.43	GO:0032870	cellular response to hormone stimulus
0.43	GO:0007420	brain development
0.42	GO:0010021	amylopectin biosynthetic process
0.41	GO:0050873	brown fat cell differentiation

0.70	GO:0005355	glucose transmembrane transporter activity
0.63	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.36	GO:0005158	insulin receptor binding
0.35	GO:0009679	hexose:proton symporter activity

0.58	GO:0005903	brush border
0.57	GO:0016324	apical plasma membrane
0.54	GO:0005911	cell-cell junction
0.42	GO:0032593	insulin-responsive compartment
0.41	GO:0042383	sarcolemma
0.40	GO:0030140	trans-Golgi network transport vesicle
0.40	GO:0009897	external side of plasma membrane
0.40	GO:0070062	extracellular exosome
0.40	GO:0045121	membrane raft
0.40	GO:0005768	endosome

sp|P11169|GTR3_HUMAN
Solute carrier family 2, facilitated glucose transporter member 3
Search

SLC2A3

0.75	Glucose transporter

0.70	GO:1904659	glucose transmembrane transport
0.53	GO:0070837	dehydroascorbic acid transport
0.37	GO:1904016	response to Thyroglobulin triiodothyronine
0.36	GO:0019852	L-ascorbic acid metabolic process
0.36	GO:0021987	cerebral cortex development
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0044703	multi-organism reproductive process
0.35	GO:1901700	response to oxygen-containing compound
0.35	GO:0046323	glucose import
0.35	GO:0005989	lactose biosynthetic process

0.70	GO:0005355	glucose transmembrane transporter activity
0.53	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.44	GO:0005536	glucose binding
0.36	GO:0033222	xylose binding
0.35	GO:0016936	galactoside binding
0.35	GO:0019900	kinase binding
0.34	GO:0043621	protein self-association
0.34	GO:0042910	xenobiotic transmembrane transporter activity
0.33	GO:0042802	identical protein binding

0.50	GO:0002080	acrosomal membrane
0.41	GO:0005886	plasma membrane
0.38	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0035579	specific granule membrane
0.36	GO:0070821	tertiary granule membrane
0.36	GO:0045121	membrane raft
0.35	GO:0030672	synaptic vesicle membrane
0.35	GO:0001939	female pronucleus

sp|P11171|41_HUMAN
Protein 4.1
Search

EPB41

0.96	Erythrocyte membrane protein band 4.1

0.83	GO:0030866	cortical actin cytoskeleton organization
0.72	GO:1904778	positive regulation of protein localization to cell cortex
0.68	GO:0032092	positive regulation of protein binding
0.56	GO:0008360	regulation of cell shape
0.51	GO:0031032	actomyosin structure organization
0.38	GO:0006461	protein complex assembly

0.72	GO:0003779	actin binding
0.67	GO:0047485	protein N-terminus binding
0.66	GO:0051219	phosphoprotein binding
0.66	GO:0005545	1-phosphatidylinositol binding
0.66	GO:0008022	protein C-terminus binding
0.61	GO:0005198	structural molecule activity
0.40	GO:0030507	spectrin binding

0.69	GO:0005856	cytoskeleton
0.66	GO:0099738	cell cortex region
0.59	GO:0030054	cell junction
0.55	GO:0005829	cytosol
0.50	GO:0043234	protein complex
0.48	GO:0005886	plasma membrane
0.41	GO:0014069	postsynaptic density
0.40	GO:0098562	cytoplasmic side of membrane

sp|P11172|UMPS_HUMAN
Uridine 5'-monophosphate synthase
Search

UMPS

0.44	Uridine monophosphate synthetase

0.74	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.72	GO:0044205	'de novo' UMP biosynthetic process
0.41	GO:0007595	lactation
0.41	GO:0007565	female pregnancy
0.40	GO:0035690	cellular response to drug
0.39	GO:0046686	response to cadmium ion
0.39	GO:0016036	cellular response to phosphate starvation
0.34	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0065009	regulation of molecular function
0.33	GO:0006468	protein phosphorylation

0.78	GO:0004590	orotidine-5'-phosphate decarboxylase activity
0.77	GO:0004588	orotate phosphoribosyltransferase activity
0.37	GO:0042802	identical protein binding
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:4.1.1.23	GO:0004590
0.78	KEGG:R00965	GO:0004590

sp|P11177|ODPB_HUMAN
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Search

PDHB

0.55	Mitochondrial pyruvate dehydrogenase e1 component subunit beta

0.58	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.51	GO:0006099	tricarboxylic acid cycle
0.46	GO:0043473	pigmentation
0.39	GO:0019362	pyridine nucleotide metabolic process
0.39	GO:0006006	glucose metabolic process
0.38	GO:0006757	ATP generation from ADP
0.38	GO:0016052	carbohydrate catabolic process
0.37	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.33	GO:0006508	proteolysis

0.62	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.46	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity
0.34	GO:0008234	cysteine-type peptidase activity
0.34	GO:0005515	protein binding

0.56	GO:0045254	pyruvate dehydrogenase complex
0.51	GO:0031974	membrane-enclosed lumen
0.49	GO:0044428	nuclear part
0.47	GO:0005739	mitochondrion
0.38	GO:0070062	extracellular exosome

0.62	EC:1.2.1	GO:0034604
0.62	KEGG:R00209	GO:0034604

sp|P11182|ODB2_HUMAN
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
Search

DBT

0.44	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

0.52	GO:0009083	branched-chain amino acid catabolic process
0.37	GO:0034641	cellular nitrogen compound metabolic process

0.76	GO:0043754	dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity
0.66	GO:0031625	ubiquitin protein ligase binding

0.69	GO:0042645	mitochondrial nucleoid
0.55	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex

0.76

EC:2.3.1.168

GO:0043754

sp|P11215|ITAM_HUMAN
Integrin alpha-M
Search

ITGAM

0.93	Integrin subunit alpha M

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.63	GO:0043315	positive regulation of neutrophil degranulation
0.61	GO:0010668	ectodermal cell differentiation
0.61	GO:0032930	positive regulation of superoxide anion generation
0.51	GO:0050798	activated T cell proliferation
0.50	GO:2000361	regulation of prostaglandin-E synthase activity
0.50	GO:0045963	negative regulation of dopamine metabolic process
0.49	GO:1903533	regulation of protein targeting
0.49	GO:0090316	positive regulation of intracellular protein transport

0.54	GO:0031072	heat shock protein binding
0.50	GO:0001851	complement component C3b binding
0.45	GO:0043395	heparan sulfate proteoglycan binding
0.44	GO:0008201	heparin binding
0.43	GO:0046982	protein heterodimerization activity
0.38	GO:0046872	metal ion binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0004872	receptor activity

0.81	GO:0008305	integrin complex
0.57	GO:0044853	plasma membrane raft
0.57	GO:0009986	cell surface
0.52	GO:0005615	extracellular space
0.48	GO:0098552	side of membrane
0.44	GO:1903561	extracellular vesicle
0.41	GO:0070821	tertiary granule membrane
0.39	GO:0035579	specific granule membrane
0.38	GO:0005634	nucleus
0.37	GO:0101003	ficolin-1-rich granule membrane

sp|P11216|PYGB_HUMAN
Glycogen phosphorylase, brain form
Search

PYGB

0.58	Glycogen phosphorylase, muscle form

0.74	GO:0005977	glycogen metabolic process
0.67	GO:0009251	glucan catabolic process
0.67	GO:0044247	cellular polysaccharide catabolic process
0.48	GO:0043312	neutrophil degranulation

0.80	GO:0008184	glycogen phosphorylase activity
0.79	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.79	GO:0102499	SHG alpha-glucan phosphorylase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.47	GO:0005515	protein binding
0.44	GO:1901265	nucleoside phosphate binding
0.42	GO:0030246	carbohydrate binding

0.56	GO:0070062	extracellular exosome
0.51	GO:0030424	axon
0.50	GO:0030016	myofibril
0.49	GO:0035578	azurophil granule lumen
0.44	GO:0044449	contractile fiber part
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P11217|PYGM_HUMAN
Glycogen phosphorylase, muscle form
Search

PYGM

0.68	Glycogen phosphorylase, muscle form

0.74	GO:0005977	glycogen metabolic process
0.68	GO:0009251	glucan catabolic process
0.68	GO:0044247	cellular polysaccharide catabolic process
0.46	GO:0051591	response to cAMP
0.46	GO:0043312	neutrophil degranulation
0.45	GO:0001666	response to hypoxia
0.44	GO:0006874	cellular calcium ion homeostasis

0.80	GO:0008184	glycogen phosphorylase activity
0.79	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.79	GO:0102499	SHG alpha-glucan phosphorylase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.48	GO:0005515	protein binding
0.46	GO:1901265	nucleoside phosphate binding
0.46	GO:0030246	carbohydrate binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0043169	cation binding

0.58	GO:0070062	extracellular exosome
0.50	GO:0030016	myofibril
0.49	GO:0030424	axon
0.47	GO:0035578	azurophil granule lumen
0.46	GO:0016529	sarcoplasmic reticulum
0.45	GO:0044449	contractile fiber part
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P11226|MBL2_HUMAN
Mannose-binding protein C
Search

MBL2

0.88	Pulmonary surfactant-associated protein A

0.85	GO:0001867	complement activation, lectin pathway
0.54	GO:0044130	negative regulation of growth of symbiont in host
0.53	GO:0006958	complement activation, classical pathway
0.52	GO:0050830	defense response to Gram-positive bacterium
0.51	GO:0048525	negative regulation of viral process
0.48	GO:0051873	killing by host of symbiont cells
0.46	GO:0050766	positive regulation of phagocytosis
0.40	GO:0033622	integrin activation
0.40	GO:0051894	positive regulation of focal adhesion assembly
0.40	GO:0033627	cell adhesion mediated by integrin

0.83	GO:0005537	mannose binding
0.52	GO:0048306	calcium-dependent protein binding
0.48	GO:0005102	receptor binding
0.42	GO:0005509	calcium ion binding
0.39	GO:0050839	cell adhesion molecule binding
0.38	GO:0032403	protein complex binding
0.37	GO:0005201	extracellular matrix structural constituent
0.36	GO:0002020	protease binding
0.36	GO:0070273	phosphatidylinositol-4-phosphate binding
0.35	GO:0043621	protein self-association

0.72	GO:0005581	collagen trimer
0.51	GO:0005576	extracellular region
0.35	GO:0009986	cell surface
0.32	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

0.34

GO:0004252

sp|P11229|ACM1_HUMAN
Muscarinic acetylcholine receptor M1
Search

CHRM1

0.76	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.82	GO:0022600	digestive system process
0.79	GO:0032941	secretion by tissue
0.77	GO:0007589	body fluid secretion
0.68	GO:0050890	cognition
0.64	GO:0040012	regulation of locomotion
0.60	GO:0007603	phototransduction, visible light
0.60	GO:0006940	regulation of smooth muscle contraction
0.59	GO:0009649	entrainment of circadian clock
0.57	GO:0043270	positive regulation of ion transport

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.37	GO:0004435	phosphatidylinositol phospholipase C activity
0.35	GO:0008144	drug binding
0.34	GO:0016934	extracellularly glycine-gated chloride channel activity
0.34	GO:0042562	hormone binding
0.34	GO:0070405	ammonium ion binding
0.34	GO:0042165	neurotransmitter binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.42	GO:0043679	axon terminus
0.41	GO:0014069	postsynaptic density
0.41	GO:0030425	dendrite
0.34	GO:0016323	basolateral plasma membrane

0.37	EC:3.1.4.11	GO:0004435
0.37	KEGG:R03435	GO:0004435

sp|P11230|ACHB_HUMAN
Acetylcholine receptor subunit beta
Search

CHRNB1

0.97	Acetylcholine receptor subunit beta

0.79	GO:0060079	excitatory postsynaptic potential
0.63	GO:0007271	synaptic transmission, cholinergic
0.61	GO:0035095	behavioral response to nicotine
0.60	GO:0034220	ion transmembrane transport
0.60	GO:0007274	neuromuscular synaptic transmission
0.59	GO:0001941	postsynaptic membrane organization
0.57	GO:0048747	muscle fiber development
0.56	GO:0006936	muscle contraction
0.52	GO:0050877	nervous system process
0.46	GO:0006812	cation transport

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.61	GO:0042166	acetylcholine binding
0.33	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.65	GO:0005892	acetylcholine-gated channel complex
0.35	GO:0009897	external side of plasma membrane
0.34	GO:0043204	perikaryon
0.33	GO:0030425	dendrite
0.33	GO:0030424	axon
0.31	GO:0005737	cytoplasm

sp|P11233|RALA_HUMAN
Ras-related protein Ral-A
Search

RALA

0.96	RAS like proto-oncogene A

0.80	GO:0007265	Ras protein signal transduction
0.56	GO:0051665	membrane raft localization
0.54	GO:0051491	positive regulation of filopodium assembly
0.52	GO:0017157	regulation of exocytosis
0.51	GO:0001843	neural tube closure
0.49	GO:0031532	actin cytoskeleton reorganization
0.41	GO:0071360	cellular response to exogenous dsRNA
0.41	GO:2000786	positive regulation of autophagosome assembly
0.40	GO:0032092	positive regulation of protein binding
0.40	GO:0032091	negative regulation of protein binding

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.57	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.55	GO:0051117	ATPase binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0017022	myosin binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0004713	protein tyrosine kinase activity

0.55	GO:0005886	plasma membrane
0.53	GO:0097610	cell surface furrow
0.52	GO:0032155	cell division site part
0.51	GO:0030139	endocytic vesicle
0.50	GO:0043209	myelin sheath
0.43	GO:0030496	midbody
0.40	GO:0005776	autophagosome
0.39	GO:0000145	exocyst
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.34

GO:0004713

sp|P11234|RALB_HUMAN
Ras-related protein Ral-B
Search

RALB

0.45	RAS like proto-oncogene B

0.82	GO:0007265	Ras protein signal transduction
0.55	GO:0071360	cellular response to exogenous dsRNA
0.55	GO:2000786	positive regulation of autophagosome assembly
0.53	GO:0032092	positive regulation of protein binding
0.53	GO:0032091	negative regulation of protein binding
0.51	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.50	GO:0009267	cellular response to starvation
0.46	GO:0017157	regulation of exocytosis
0.45	GO:0051665	membrane raft localization
0.44	GO:0051491	positive regulation of filopodium assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.57	GO:0051117	ATPase binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.43	GO:0017022	myosin binding
0.34	GO:0004713	protein tyrosine kinase activity

0.55	GO:0005886	plasma membrane
0.53	GO:0030496	midbody
0.53	GO:0005776	autophagosome
0.50	GO:0000145	exocyst
0.44	GO:0097610	cell surface furrow
0.43	GO:0032155	cell division site part
0.43	GO:0030139	endocytic vesicle
0.41	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.34

GO:0004713

sp|P11245|ARY2_HUMAN
Arylamine N-acetyltransferase 2
Search

NAT2

0.92	Arylamine N-acetyltransferase 2

0.38	GO:0097068	response to thyroxine
0.37	GO:0001889	liver development
0.36	GO:0009410	response to xenobiotic stimulus
0.36	GO:0007568	aging
0.36	GO:1902475	L-alpha-amino acid transmembrane transport
0.34	GO:0070887	cellular response to chemical stimulus
0.34	GO:0048565	digestive tract development
0.34	GO:0032496	response to lipopolysaccharide
0.34	GO:0001666	response to hypoxia
0.32	GO:0055114	oxidation-reduction process

0.67	GO:0016407	acetyltransferase activity
0.45	GO:0016410	N-acyltransferase activity
0.36	GO:0015179	L-amino acid transmembrane transporter activity
0.33	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.37	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.67

EC:2.3.1

GO:0016407

sp|P11274|BCR_HUMAN
Breakpoint cluster region protein
Search

BCR

0.88	Breakpoint cluster region

0.76	GO:0035023	regulation of Rho protein signal transduction
0.76	GO:0043547	positive regulation of GTPase activity
0.61	GO:0035556	intracellular signal transduction
0.58	GO:0043314	negative regulation of neutrophil degranulation
0.58	GO:0060313	negative regulation of blood vessel remodeling
0.58	GO:0060268	negative regulation of respiratory burst
0.57	GO:0002692	negative regulation of cellular extravasation
0.56	GO:0006468	protein phosphorylation
0.56	GO:0043114	regulation of vascular permeability
0.56	GO:0060216	definitive hemopoiesis

0.76	GO:0005096	GTPase activator activity
0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.62	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0004713	protein tyrosine kinase activity
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding

0.54	GO:0014069	postsynaptic density
0.47	GO:0005829	cytosol
0.43	GO:0043234	protein complex
0.41	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0030054	cell junction
0.30	GO:0044425	membrane part

0.62

GO:0004674

sp|P11277|SPTB1_HUMAN
Spectrin beta chain, erythrocytic
Search

SPTB

0.76	Spectrin beta chain, erythrocytic

0.80	GO:0051693	actin filament capping
0.70	GO:0007010	cytoskeleton organization
0.47	GO:0007184	SMAD protein import into nucleus
0.47	GO:0007182	common-partner SMAD protein phosphorylation
0.47	GO:1900042	positive regulation of interleukin-2 secretion
0.46	GO:0007009	plasma membrane organization
0.45	GO:1903078	positive regulation of protein localization to plasma membrane
0.45	GO:0043001	Golgi to plasma membrane protein transport
0.44	GO:0000281	mitotic cytokinesis
0.43	GO:0030097	hemopoiesis

0.76	GO:0005200	structural constituent of cytoskeleton
0.73	GO:0003779	actin binding
0.70	GO:0005543	phospholipid binding
0.61	GO:0030506	ankyrin binding
0.52	GO:0032403	protein complex binding
0.44	GO:0045296	cadherin binding
0.42	GO:0051020	GTPase binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0003723	RNA binding
0.35	GO:0098772	molecular function regulator

0.85	GO:0008091	spectrin
0.59	GO:0014731	spectrin-associated cytoskeleton
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.47	GO:0032437	cuticular plate
0.46	GO:0030673	axolemma
0.46	GO:0031430	M band
0.45	GO:0014069	postsynaptic density
0.45	GO:0043234	protein complex
0.42	GO:0005730	nucleolus

sp|P11279|LAMP1_HUMAN
Lysosome-associated membrane glycoprotein 1
Search

LAMP1

0.94	Lysosomal-associated membrane glycoprotein 1

0.59	GO:0043323	positive regulation of natural killer cell degranulation
0.58	GO:1902513	regulation of organelle transport along microtubule
0.58	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.58	GO:0090160	Golgi to lysosome transport
0.54	GO:0050821	protein stabilization
0.50	GO:0072594	establishment of protein localization to organelle
0.43	GO:0048102	autophagic cell death
0.37	GO:0043312	neutrophil degranulation
0.35	GO:0051704	multi-organism process
0.35	GO:0048609	multicellular organismal reproductive process

0.52	GO:0019904	protein domain specific binding
0.49	GO:0019899	enzyme binding
0.37	GO:0104005	hijacked molecular function
0.34	GO:0005509	calcium ion binding
0.34	GO:0004252	serine-type endopeptidase activity

0.82	GO:0005765	lysosomal membrane
0.59	GO:0044194	cytolytic granule
0.59	GO:0032010	phagolysosome
0.58	GO:0044754	autolysosome
0.57	GO:0030670	phagocytic vesicle membrane
0.57	GO:0005771	multivesicular body
0.56	GO:0042470	melanosome
0.55	GO:0042383	sarcolemma
0.54	GO:0008021	synaptic vesicle
0.54	GO:0009897	external side of plasma membrane

0.34

GO:0004252

sp|P11308|ERG_HUMAN
Transcriptional regulator ERG
Search

ERG

0.88	Transcriptional regulator ERG

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:2000504	positive regulation of blood vessel remodeling
0.46	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation
0.45	GO:0003197	endocardial cushion development
0.42	GO:0016477	cell migration
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:0008283	cell proliferation
0.36	GO:0006351	transcription, DNA-templated

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003682	chromatin binding
0.41	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0004871	signal transducer activity

0.61	GO:0005634	nucleus
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005737	cytoplasm

sp|P11309|PIM1_HUMAN
Serine/threonine-protein kinase pim-1
Search

PIM1

0.93	Proto-oncogene serine/threonine-protein kinase pim-1

0.76	GO:0043066	negative regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.56	GO:1905062	positive regulation of cardioblast proliferation
0.54	GO:0070561	vitamin D receptor signaling pathway
0.54	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.51	GO:0043433	negative regulation of DNA binding transcription factor activity
0.50	GO:0008283	cell proliferation
0.50	GO:0007346	regulation of mitotic cell cycle
0.46	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.44	GO:0007634	optokinetic behavior

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0043024	ribosomal small subunit binding
0.47	GO:0008134	transcription factor binding
0.47	GO:0030145	manganese ion binding
0.33	GO:0005509	calcium ion binding

0.49	GO:0005829	cytosol
0.48	GO:0005730	nucleolus
0.34	GO:0005886	plasma membrane
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

sp|P11310|ACADM_HUMAN
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADM

0.89	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

0.71	GO:0006635	fatty acid beta-oxidation
0.52	GO:0019254	carnitine metabolic process, CoA-linked
0.51	GO:0051791	medium-chain fatty acid metabolic process
0.48	GO:0055007	cardiac muscle cell differentiation
0.48	GO:0001889	liver development
0.48	GO:0006111	regulation of gluconeogenesis
0.47	GO:0009409	response to cold
0.46	GO:0009791	post-embryonic development
0.46	GO:0042594	response to starvation
0.45	GO:0005978	glycogen biosynthetic process

0.84	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0042802	identical protein binding
0.35	GO:0004663	Rab geranylgeranyltransferase activity
0.35	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0030983	mismatched DNA binding
0.33	GO:0016853	isomerase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.57	GO:0005739	mitochondrion
0.48	GO:0016607	nuclear speck
0.37	GO:0030424	axon
0.36	GO:0070062	extracellular exosome
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:1.3.99

GO:0070991

sp|P11362|FGFR1_HUMAN
Fibroblast growth factor receptor 1
Search

FGFR1

0.73	Fibroblast growth factor receptor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.77	GO:0008284	positive regulation of cell proliferation
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.59	GO:2000830	positive regulation of parathyroid hormone secretion
0.58	GO:0021769	orbitofrontal cortex development
0.58	GO:0048378	regulation of lateral mesodermal cell fate specification
0.58	GO:0021847	ventricular zone neuroblast division
0.58	GO:1903465	positive regulation of mitotic cell cycle DNA replication
0.58	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor
0.58	GO:0090272	negative regulation of fibroblast growth factor production

0.85	GO:0005007	fibroblast growth factor-activated receptor activity
0.58	GO:0090722	receptor-receptor interaction
0.56	GO:0017134	fibroblast growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0008201	heparin binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.50	GO:0042803	protein homodimerization activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.51	GO:0043235	receptor complex
0.48	GO:0005730	nucleolus
0.42	GO:0005886	plasma membrane
0.38	GO:0031410	cytoplasmic vesicle
0.38	GO:0005829	cytosol
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P11387|TOP1_HUMAN
DNA topoisomerase 1
Search

0.42	Topoisomerase I beta

0.72	GO:0006265	DNA topological change
0.44	GO:0006338	chromatin remodeling
0.44	GO:0040016	embryonic cleavage
0.43	GO:0032922	circadian regulation of gene expression
0.42	GO:0018105	peptidyl-serine phosphorylation
0.41	GO:0006260	DNA replication
0.39	GO:0007059	chromosome segregation
0.39	GO:0042493	response to drug
0.33	GO:0071373	cellular response to luteinizing hormone stimulus
0.33	GO:0012501	programmed cell death

0.76	GO:0003917	DNA topoisomerase type I activity
0.55	GO:0003677	DNA binding
0.41	GO:0003682	chromatin binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0019904	protein domain specific binding
0.39	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032403	protein complex binding

0.67	GO:0005694	chromosome
0.43	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)
0.43	GO:0005730	nucleolus
0.43	GO:0043204	perikaryon
0.42	GO:0000932	P-body
0.40	GO:0032993	protein-DNA complex
0.39	GO:0005654	nucleoplasm
0.38	GO:0019013	viral nucleocapsid
0.32	GO:0044815	DNA packaging complex

0.76

EC:5.99.1.2

GO:0003917

sp|P11388|TOP2A_HUMAN
DNA topoisomerase 2-alpha
Search

TOP2A

0.64	DNA topoisomerase 2-alpha

0.72	GO:0006265	DNA topological change
0.61	GO:0045870	positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.61	GO:0030263	apoptotic chromosome condensation
0.59	GO:1905463	negative regulation of DNA duplex unwinding
0.59	GO:0040016	embryonic cleavage
0.57	GO:0048513	animal organ development
0.55	GO:0030154	cell differentiation
0.55	GO:0042752	regulation of circadian rhythm
0.53	GO:0007059	chromosome segregation
0.53	GO:0043065	positive regulation of apoptotic process

0.74	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity
0.65	GO:0005080	protein kinase C binding
0.63	GO:0042826	histone deacetylase binding
0.62	GO:0008022	protein C-terminus binding
0.58	GO:0003682	chromatin binding
0.57	GO:0008301	DNA binding, bending
0.57	GO:0046982	protein heterodimerization activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0043130	ubiquitin binding
0.54	GO:0097367	carbohydrate derivative binding

0.58	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)
0.55	GO:0005814	centriole
0.54	GO:0005654	nucleoplasm
0.53	GO:0005694	chromosome
0.51	GO:0005730	nucleolus
0.46	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005829	cytosol
0.37	GO:0019035	viral integration complex
0.31	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.74

EC:5.99.1.3

GO:0003918

sp|P11413|G6PD_HUMAN
Glucose-6-phosphate 1-dehydrogenase
Search

G6PD

0.42	Glucose-6-phosphate 1-dehydrogenase X

0.71	GO:0006006	glucose metabolic process
0.71	GO:0006098	pentose-phosphate shunt
0.56	GO:0019322	pentose biosynthetic process
0.56	GO:0010732	regulation of protein glutathionylation
0.54	GO:0043249	erythrocyte maturation
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0006695	cholesterol biosynthetic process
0.49	GO:0006749	glutathione metabolic process
0.48	GO:0034599	cellular response to oxidative stress
0.48	GO:0031400	negative regulation of protein modification process

0.79	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.70	GO:0050661	NADP binding
0.51	GO:0005536	glucose binding
0.48	GO:0042803	protein homodimerization activity

0.48	GO:0009898	cytoplasmic side of plasma membrane
0.45	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.1.1.49

GO:0004345

sp|P11441|UBL4A_HUMAN
Ubiquitin-like protein 4A
Search

UBL4A

0.97	Ubiquitin like 4A

0.84	GO:0071816	tail-anchored membrane protein insertion into ER membrane
0.36	GO:1903955	positive regulation of protein targeting to mitochondrion
0.36	GO:0055085	transmembrane transport
0.36	GO:0036211	protein modification process
0.35	GO:0044267	cellular protein metabolic process

0.68	GO:0051087	chaperone binding
0.38	GO:0019787	ubiquitin-like protein transferase activity

0.86	GO:0071818	BAT3 complex
0.63	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P11464|PSG1_HUMAN
Pregnancy-specific beta-1-glycoprotein 1
Search

PSG3

0.91	Pregnancy-specific beta-1-glycoprotein 8

0.77	GO:0007565	female pregnancy
0.42	GO:0043312	neutrophil degranulation
0.41	GO:0030335	positive regulation of cell migration
0.41	GO:0050900	leukocyte migration
0.41	GO:0008284	positive regulation of cell proliferation
0.37	GO:0007267	cell-cell signaling
0.35	GO:0007165	signal transduction

0.38

GO:0005515

protein binding

0.45	GO:0005576	extracellular region
0.41	GO:0030667	secretory granule membrane
0.39	GO:0005766	primary lysosome
0.38	GO:0005765	lysosomal membrane
0.38	GO:0042581	specific granule
0.38	GO:0031225	anchored component of membrane
0.36	GO:0005887	integral component of plasma membrane

sp|P11465|PSG2_HUMAN
Pregnancy-specific beta-1-glycoprotein 2
Search

0.96	Pregnancy-specific beta-1-glycoprotein 2

0.75	GO:0007565	female pregnancy
0.47	GO:0016477	cell migration
0.45	GO:0043317	regulation of cytotoxic T cell degranulation
0.44	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.44	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.44	GO:0030334	regulation of cell migration
0.43	GO:0043301	negative regulation of leukocyte degranulation
0.43	GO:0050860	negative regulation of T cell receptor signaling pathway
0.43	GO:0090505	epiboly involved in wound healing
0.42	GO:0050868	negative regulation of T cell activation

0.43	GO:0031005	filamin binding
0.42	GO:1990782	protein tyrosine kinase binding
0.42	GO:0019903	protein phosphatase binding
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0003779	actin binding
0.38	GO:0015125	bile acid transmembrane transporter activity
0.38	GO:0034235	GPI anchor binding
0.36	GO:0005516	calmodulin binding

0.49	GO:0005576	extracellular region
0.43	GO:0042101	T cell receptor complex
0.41	GO:0009986	cell surface
0.41	GO:0031982	vesicle
0.40	GO:0005911	cell-cell junction
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0031225	anchored component of membrane
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0005887	integral component of plasma membrane

sp|P11473|VDR_HUMAN
Vitamin D3 receptor
Search

VDR

0.96	Vitamin D receptor alpha

0.86	GO:0070561	vitamin D receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0038183	bile acid signaling pathway
0.57	GO:0010979	regulation of vitamin D 24-hydroxylase activity
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0045618	positive regulation of keratinocyte differentiation
0.56	GO:0010839	negative regulation of keratinocyte proliferation

0.87	GO:0008434	calcitriol receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.59	GO:1902098	calcitriol binding
0.59	GO:1902121	lithocholic acid binding
0.59	GO:0038186	lithocholic acid receptor activity
0.56	GO:0046965	retinoid X receptor binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0043235	receptor complex
0.49	GO:0005667	transcription factor complex
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.36	GO:0005901	caveola
0.35	GO:0005737	cytoplasm
0.35	GO:0030315	T-tubule
0.33	GO:0005694	chromosome

0.54

EC:1.97.1

GO:0051353

sp|P11474|ERR1_HUMAN
Steroid hormone receptor ERR1
Search

ESRRA

0.97	Steroid hormone receptor ERR1

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process
0.48	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process

0.80	GO:0003707	steroid hormone receptor activity
0.79	GO:0005496	steroid binding
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0019904	protein domain specific binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.36	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.36	GO:0000993	RNA polymerase II core binding

0.61	GO:0005634	nucleus
0.56	GO:0045171	intercellular bridge
0.49	GO:0015630	microtubule cytoskeleton
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.35	GO:0000793	condensed chromosome
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32

GO:0016491

sp|P11487|FGF3_HUMAN
Fibroblast growth factor 3
Search

FGF3

0.60	Fibroblast growth factor

0.83	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.58	GO:0055026	negative regulation of cardiac muscle tissue development
0.53	GO:0008284	positive regulation of cell proliferation
0.50	GO:0030916	otic vesicle formation
0.49	GO:0021572	rhombomere 6 development
0.49	GO:0021985	neurohypophysis development
0.48	GO:0060118	vestibular receptor cell development
0.48	GO:0021703	locus ceruleus development
0.48	GO:0021571	rhombomere 5 development

0.84	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity
0.35	GO:0042056	chemoattractant activity
0.34	GO:0008201	heparin binding

0.66	GO:0005576	extracellular region
0.37	GO:0005794	Golgi apparatus
0.35	GO:0009986	cell surface
0.35	GO:0005634	nucleus
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|P11488|GNAT1_HUMAN
Guanine nucleotide-binding protein G(t) subunit alpha-1
Search

GNAT1

0.79	Short photoreceptor transducin-alpha subunit

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.62	GO:0050917	sensory perception of umami taste
0.61	GO:0050908	detection of light stimulus involved in visual perception
0.59	GO:0042462	eye photoreceptor cell development
0.57	GO:0060041	retina development in camera-type eye
0.56	GO:0007602	phototransduction
0.55	GO:0071257	cellular response to electrical stimulus
0.54	GO:0050913	sensory perception of bitter taste
0.50	GO:0008283	cell proliferation
0.50	GO:0050916	sensory perception of sweet taste

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0001664	G-protein coupled receptor binding
0.37	GO:0000035	acyl binding
0.36	GO:0046872	metal ion binding

0.62	GO:0001917	photoreceptor inner segment
0.61	GO:0001750	photoreceptor outer segment
0.53	GO:0032391	photoreceptor connecting cilium
0.51	GO:1905360	GTPase complex
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0098797	plasma membrane protein complex
0.41	GO:0098590	plasma membrane region
0.41	GO:0045177	apical part of cell
0.38	GO:0030141	secretory granule
0.38	GO:0043025	neuronal cell body

sp|P11498|PYC_HUMAN
Pyruvate carboxylase, mitochondrial
Search

0.55	Pyruvate carboxylase, mitochondrial

0.69	GO:0019319	hexose biosynthetic process
0.68	GO:0006006	glucose metabolic process
0.65	GO:0006090	pyruvate metabolic process
0.56	GO:0044791	positive regulation by host of viral release from host cell
0.55	GO:0019074	viral RNA genome packaging
0.46	GO:0010629	negative regulation of gene expression
0.40	GO:0046686	response to cadmium ion
0.37	GO:0046959	habituation
0.36	GO:0006629	lipid metabolic process
0.35	GO:0071073	positive regulation of phospholipid biosynthetic process

0.78	GO:0009374	biotin binding
0.78	GO:0004736	pyruvate carboxylase activity
0.73	GO:0004075	biotin carboxylase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.48	GO:0042802	identical protein binding
0.33	GO:0016829	lyase activity

0.43	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.34	GO:0005829	cytosol

0.78	EC:6.4.1.1	GO:0004736
0.78	KEGG:R00344	GO:0004736

sp|P11509|CP2A6_HUMAN
Cytochrome P450 2A6
Search

0.97	Felis catus cytochrome P450, family 2, subfamily A, polypeptide 13

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0019373	epoxygenase P450 pathway

0.77	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0008392	arachidonic acid epoxygenase activity
0.45	GO:0008395	steroid hydroxylase activity

0.77

GO:0016712

sp|P11511|CP19A_HUMAN
Aromatase
Search

CYP19A1

0.81

Aromatase

0.62	GO:2000866	positive regulation of estradiol secretion
0.62	GO:0006710	androgen catabolic process
0.61	GO:0002677	negative regulation of chronic inflammatory response
0.61	GO:0010760	negative regulation of macrophage chemotaxis
0.60	GO:0061370	testosterone biosynthetic process
0.60	GO:0060736	prostate gland growth
0.59	GO:0030540	female genitalia development
0.59	GO:0060065	uterus development
0.58	GO:0008585	female gonad development
0.55	GO:0030879	mammary gland development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0019825	oxygen binding
0.33	GO:0009055	electron transfer activity

0.50	GO:0005783	endoplasmic reticulum
0.38	GO:0044297	cell body
0.38	GO:0043195	terminal bouton
0.37	GO:0030425	dendrite
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.35	GO:0044309	neuron spine
0.34	GO:0008021	synaptic vesicle
0.34	GO:0098794	postsynapse
0.33	GO:0005829	cytosol

0.68

GO:0016705

sp|P11532|DMD_HUMAN
Dystrophin
Search

DMD

0.69	Dystrophin

0.51	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
0.50	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.50	GO:0021629	olfactory nerve structural organization
0.50	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.49	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.49	GO:0035994	response to muscle stretch
0.49	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.49	GO:0008065	establishment of blood-nerve barrier
0.49	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.49	GO:0086001	cardiac muscle cell action potential

0.86	GO:0002162	dystroglycan binding
0.74	GO:0003779	actin binding
0.59	GO:0008270	zinc ion binding
0.50	GO:0050998	nitric-oxide synthase binding
0.43	GO:0017166	vinculin binding
0.43	GO:0005521	lamin binding
0.43	GO:0008307	structural constituent of muscle
0.42	GO:0030165	PDZ domain binding
0.42	GO:0005178	integrin binding
0.42	GO:0017022	myosin binding

0.62	GO:0045211	postsynaptic membrane
0.59	GO:0030054	cell junction
0.55	GO:0005856	cytoskeleton
0.49	GO:0042383	sarcolemma
0.47	GO:0044306	neuron projection terminus
0.47	GO:0030018	Z disc
0.47	GO:0016010	dystrophin-associated glycoprotein complex
0.46	GO:0098857	membrane microdomain
0.44	GO:0099617	matrix side of mitochondrial inner membrane
0.43	GO:0097449	astrocyte projection

sp|P11586|C1TC_HUMAN
C-1-tetrahydrofolate synthase, cytoplasmic
Search

MTHFD1

0.90	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

0.60	GO:0009257	10-formyltetrahydrofolate biosynthetic process
0.56	GO:0001780	neutrophil homeostasis
0.55	GO:0019346	transsulfuration
0.54	GO:0001843	neural tube closure
0.53	GO:0061053	somite development
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0007507	heart development
0.50	GO:0035999	tetrahydrofolate interconversion
0.48	GO:0009086	methionine biosynthetic process
0.48	GO:0009070	serine family amino acid biosynthetic process

0.81	GO:0004329	formate-tetrahydrofolate ligase activity
0.78	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.56	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity
0.38	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
0.33	GO:0005515	protein binding

0.47	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81	EC:6.3.4.3	GO:0004329
0.78	KEGG:R01220	GO:0004488

sp|P11597|CETP_HUMAN
Cholesteryl ester transfer protein
Search

CETP

0.97	Cholesteryl ester transfer protein, plasma

0.86	GO:0043691	reverse cholesterol transport
0.65	GO:0034197	triglyceride transport
0.64	GO:0034372	very-low-density lipoprotein particle remodeling
0.63	GO:0034375	high-density lipoprotein particle remodeling
0.61	GO:0034374	low-density lipoprotein particle remodeling
0.60	GO:0055091	phospholipid homeostasis
0.60	GO:0010874	regulation of cholesterol efflux
0.59	GO:0008203	cholesterol metabolic process
0.59	GO:0070328	triglyceride homeostasis
0.58	GO:0042632	cholesterol homeostasis

0.85	GO:0017127	cholesterol transporter activity
0.72	GO:0008289	lipid binding
0.60	GO:0050997	quaternary ammonium group binding
0.56	GO:0070405	ammonium ion binding
0.56	GO:0043178	alcohol binding
0.55	GO:0005548	phospholipid transporter activity
0.42	GO:0043168	anion binding
0.38	GO:0097159	organic cyclic compound binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.85	GO:0034364	high-density lipoprotein particle
0.51	GO:0031982	vesicle
0.37	GO:0043230	extracellular organelle

sp|P11678|PERE_HUMAN
Eosinophil peroxidase
Search

MPO

0.94	Eosinophil peroxidase

0.72	GO:0006952	defense response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.63	GO:0002148	hypochlorous acid metabolic process
0.61	GO:0018969	thiocyanate metabolic process
0.58	GO:1903409	reactive oxygen species biosynthetic process
0.56	GO:0009617	response to bacterium
0.55	GO:0032714	negative regulation of interleukin-5 production
0.54	GO:0072677	eosinophil migration
0.54	GO:0032693	negative regulation of interleukin-10 production

0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.50	GO:0008201	heparin binding
0.35	GO:0030156	benzodiazepine receptor binding
0.35	GO:0046872	metal ion binding
0.34	GO:0004984	olfactory receptor activity
0.34	GO:0003682	chromatin binding

0.53	GO:0005615	extracellular space
0.52	GO:0005766	primary lysosome
0.50	GO:0030141	secretory granule
0.44	GO:0016323	basolateral plasma membrane
0.42	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.40	GO:1903561	extracellular vesicle
0.37	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.72	EC:1.11.1.7	GO:0004601
0.72	KEGG:R03532	GO:0004601

sp|P11684|UTER_HUMAN
Uteroglobin
Search

SCGB1A1

0.97	Uteroglobin

0.61	GO:0032696	negative regulation of interleukin-13 production
0.61	GO:0032714	negative regulation of interleukin-5 production
0.61	GO:0032713	negative regulation of interleukin-4 production
0.60	GO:0007165	signal transduction
0.59	GO:0032689	negative regulation of interferon-gamma production
0.58	GO:0042130	negative regulation of T cell proliferation
0.57	GO:0043488	regulation of mRNA stability
0.55	GO:0050727	regulation of inflammatory response
0.54	GO:0034021	response to silicon dioxide
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II

0.55	GO:0097160	polychlorinated biphenyl binding
0.55	GO:0019834	phospholipase A2 inhibitor activity
0.37	GO:0005515	protein binding
0.36	GO:0005550	pheromone binding

0.60	GO:0005615	extracellular space
0.49	GO:0005791	rough endoplasmic reticulum
0.48	GO:0030141	secretory granule
0.46	GO:0005635	nuclear envelope
0.42	GO:1903561	extracellular vesicle

sp|P11686|PSPC_HUMAN
Pulmonary surfactant-associated protein C
Search

SFTPC

0.97	Pulmonary surfactant-associated protein C

0.85	GO:0007585	respiratory gaseous exchange
0.40	GO:0050828	regulation of liquid surface tension
0.40	GO:0033189	response to vitamin A
0.39	GO:0071732	cellular response to nitric oxide
0.39	GO:0055093	response to hyperoxia
0.39	GO:0070741	response to interleukin-6
0.39	GO:0051591	response to cAMP
0.39	GO:0071260	cellular response to mechanical stimulus
0.39	GO:0032526	response to retinoic acid
0.39	GO:0051384	response to glucocorticoid

0.53	GO:0042802	identical protein binding
0.36	GO:0046983	protein dimerization activity

0.66	GO:0005576	extracellular region
0.44	GO:0042599	lamellar body
0.43	GO:0005771	multivesicular body
0.42	GO:0031906	late endosome lumen
0.40	GO:0045334	clathrin-coated endocytic vesicle
0.38	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|P11712|CP2C9_HUMAN
Cytochrome P450 2C9
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.56	GO:0042738	exogenous drug catabolic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0008202	steroid metabolic process
0.49	GO:0002933	lipid hydroxylation
0.49	GO:0070988	demethylation
0.49	GO:0016098	monoterpenoid metabolic process
0.44	GO:0019373	epoxygenase P450 pathway
0.40	GO:0019627	urea metabolic process
0.34	GO:0046483	heterocycle metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.54	GO:0034875	caffeine oxidase activity
0.39	GO:0019899	enzyme binding
0.35	GO:0008144	drug binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P11717|MPRI_HUMAN
Cation-independent mannose-6-phosphate receptor
Search

IGF2R

0.84	Cation-independent mannose-6-phosphate receptor

0.84	GO:0007041	lysosomal transport
0.40	GO:0031100	animal organ regeneration
0.40	GO:0048009	insulin-like growth factor receptor signaling pathway
0.40	GO:0043312	neutrophil degranulation
0.40	GO:0032526	response to retinoic acid
0.40	GO:0001889	liver development
0.39	GO:0007283	spermatogenesis
0.39	GO:0043065	positive regulation of apoptotic process
0.39	GO:0009791	post-embryonic development
0.37	GO:0007186	G-protein coupled receptor signaling pathway

0.84	GO:0051219	phosphoprotein binding
0.65	GO:0004872	receptor activity
0.62	GO:0005520	insulin-like growth factor binding
0.60	GO:0005537	mannose binding
0.53	GO:0042802	identical protein binding
0.41	GO:0001972	retinoic acid binding
0.40	GO:0001965	G-protein alpha-subunit binding
0.38	GO:0004713	protein tyrosine kinase activity
0.37	GO:0019899	enzyme binding
0.36	GO:0004871	signal transducer activity

0.61	GO:0005641	nuclear envelope lumen
0.57	GO:0030140	trans-Golgi network transport vesicle
0.57	GO:0030139	endocytic vesicle
0.56	GO:0005770	late endosome
0.56	GO:0005769	early endosome
0.56	GO:0005802	trans-Golgi network
0.54	GO:0009986	cell surface
0.41	GO:0005886	plasma membrane
0.40	GO:0030667	secretory granule membrane
0.39	GO:0005765	lysosomal membrane

0.38

GO:0004713

sp|P11766|ADHX_HUMAN
Alcohol dehydrogenase class-3
Search

ADH5

0.60	S-(hydroxymethyl)glutathione dehydrogenase

0.80	GO:0006069	ethanol oxidation
0.52	GO:0018119	peptidyl-cysteine S-nitrosylation
0.51	GO:0003016	respiratory system process
0.51	GO:0045777	positive regulation of blood pressure
0.50	GO:0051775	response to redox state
0.50	GO:0001523	retinoid metabolic process
0.49	GO:0051409	response to nitrosative stress
0.49	GO:0032496	response to lipopolysaccharide
0.48	GO:0046294	formaldehyde catabolic process
0.35	GO:0006068	ethanol catabolic process

0.80	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.62	GO:0008270	zinc ion binding
0.53	GO:0018467	formaldehyde dehydrogenase activity
0.52	GO:0005504	fatty acid binding
0.50	GO:0004022	alcohol dehydrogenase (NAD) activity
0.46	GO:0042803	protein homodimerization activity
0.33	GO:0009055	electron transfer activity

0.41	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80	EC:1.1.1.284	GO:0051903
0.80	KEGG:R06983 KEGG:R07140	GO:0051903

sp|P11801|KPSH1_HUMAN
Serine/threonine-protein kinase H1
Search

PSKH1

0.68	Serine/threonine-protein kinase H1

0.63	GO:0006468	protein phosphorylation
0.57	GO:0007368	determination of left/right symmetry
0.55	GO:0007507	heart development
0.51	GO:0018210	peptidyl-threonine modification
0.50	GO:0018209	peptidyl-serine modification
0.43	GO:0035556	intracellular signal transduction

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.50	GO:0005654	nucleoplasm
0.37	GO:0005815	microtubule organizing center
0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005794	Golgi apparatus
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0004674

sp|P11802|CDK4_HUMAN
Cyclin-dependent kinase 4
Search

CDK4

0.81	Cyclin dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0043697	cell dedifferentiation
0.61	GO:0042127	regulation of cell proliferation
0.60	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.59	GO:0051726	regulation of cell cycle
0.55	GO:0000082	G1/S transition of mitotic cell cycle
0.55	GO:1904636	response to ionomycin
0.54	GO:0071362	cellular response to ether
0.53	GO:0071353	cellular response to interleukin-4
0.52	GO:0060612	adipose tissue development

0.67	GO:0004674	protein serine/threonine kinase activity
0.67	GO:0097472	cyclin-dependent protein kinase activity
0.58	GO:0030332	cyclin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0098770	FBXO family protein binding
0.38	GO:0032403	protein complex binding
0.36	GO:0030234	enzyme regulator activity

0.59	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.50	GO:0005923	bicellular tight junction
0.49	GO:0031965	nuclear membrane
0.49	GO:0005829	cytosol
0.49	GO:0031981	nuclear lumen
0.47	GO:0005667	transcription factor complex
0.46	GO:0001726	ruffle
0.46	GO:0000785	chromatin
0.45	GO:0005813	centrosome
0.39	GO:0048471	perinuclear region of cytoplasm

0.67

GO:0004674

sp|P11831|SRF_HUMAN
Serum response factor
Search

SRF

0.92	Serum response factor (C-fos serum response element-binding transcription factor)

0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.62	GO:0061145	lung smooth muscle development
0.62	GO:0060532	bronchus cartilage development
0.61	GO:0060947	cardiac vascular smooth muscle cell differentiation
0.60	GO:0060534	trachea cartilage development
0.60	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb
0.60	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.60	GO:0090009	primitive streak formation
0.60	GO:1900222	negative regulation of amyloid-beta clearance
0.60	GO:0045059	positive thymic T cell selection

0.74	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.73	GO:0000987	proximal promoter sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.60	GO:0070878	primary miRNA binding
0.57	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.57	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.56	GO:0031490	chromatin DNA binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen
0.39	GO:0005737	cytoplasm
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0031461	cullin-RING ubiquitin ligase complex
0.33	GO:0005856	cytoskeleton

sp|P11836|CD20_HUMAN
B-lymphocyte antigen CD20
Search

MS4A1

0.96	Membrane spanning 4-domains A1

0.44	GO:0023026	MHC class II protein complex binding
0.43	GO:0005154	epidermal growth factor receptor binding

0.72	GO:0009897	external side of plasma membrane
0.67	GO:0005887	integral component of plasma membrane
0.56	GO:0005634	nucleus
0.41	GO:0070062	extracellular exosome

sp|P11844|CRGA_HUMAN
Gamma-crystallin A
Search

0.97	Gamma-crystallin A

0.75	GO:0002088	lens development in camera-type eye
0.61	GO:0007601	visual perception
0.58	GO:0030855	epithelial cell differentiation
0.57	GO:0048593	camera-type eye morphogenesis
0.54	GO:0000904	cell morphogenesis involved in differentiation
0.44	GO:0034614	cellular response to reactive oxygen species
0.38	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0005515	protein binding
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P11908|PRPS2_HUMAN
Ribose-phosphate pyrophosphokinase 2
Search

PRPS2

0.80	Ribose-phosphate pyrophosphokinase II

0.66	GO:0009116	nucleoside metabolic process
0.65	GO:0009156	ribonucleoside monophosphate biosynthetic process
0.64	GO:0009165	nucleotide biosynthetic process
0.51	GO:0034418	urate biosynthetic process
0.50	GO:0016310	phosphorylation
0.47	GO:0046101	hypoxanthine biosynthetic process
0.44	GO:0048731	system development
0.44	GO:0046391	5-phosphoribose 1-diphosphate metabolic process
0.41	GO:0006163	purine nucleotide metabolic process
0.40	GO:0046390	ribose phosphate biosynthetic process

0.78	GO:0004749	ribose phosphate diphosphokinase activity
0.64	GO:0000287	magnesium ion binding
0.52	GO:0016301	kinase activity
0.51	GO:0042802	identical protein binding
0.45	GO:0046983	protein dimerization activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0019003	GDP binding
0.37	GO:0030246	carbohydrate binding

0.40	GO:0002189	ribose phosphate diphosphokinase complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol
0.33	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.78	EC:2.7.6.1	GO:0004749
0.78	KEGG:R01049	GO:0004749

sp|P11912|CD79A_HUMAN
B-cell antigen receptor complex-associated protein alpha chain
Search

CD79A

0.97	B-cell antigen receptor complex-associated protein alpha chain

0.69	GO:0007166	cell surface receptor signaling pathway
0.67	GO:0051289	protein homotetramerization
0.65	GO:0042100	B cell proliferation
0.65	GO:0030183	B cell differentiation
0.62	GO:0002757	immune response-activating signal transduction
0.44	GO:0002250	adaptive immune response
0.37	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0065009	regulation of molecular function
0.34	GO:0006518	peptide metabolic process
0.34	GO:0043604	amide biosynthetic process

0.67	GO:0004888	transmembrane signaling receptor activity
0.60	GO:0042803	protein homodimerization activity
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0046872	metal ion binding

0.70	GO:0019815	B cell receptor complex
0.64	GO:0005771	multivesicular body
0.63	GO:0009897	external side of plasma membrane
0.61	GO:0045121	membrane raft
0.46	GO:0005887	integral component of plasma membrane
0.34	GO:0005840	ribosome
0.34	GO:0005634	nucleus

sp|P11926|DCOR_HUMAN
Ornithine decarboxylase
Search

ODC1

0.48	Ornithine decarboxylase

0.74	GO:0006596	polyamine biosynthetic process
0.57	GO:0009445	putrescine metabolic process
0.55	GO:0001822	kidney development
0.54	GO:0006591	ornithine metabolic process
0.54	GO:0042176	regulation of protein catabolic process
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0009615	response to virus
0.44	GO:0042462	eye photoreceptor cell development
0.36	GO:0006521	regulation of cellular amino acid metabolic process

0.60	GO:0004586	ornithine decarboxylase activity
0.53	GO:0042803	protein homodimerization activity

0.49	GO:0005829	cytosol
0.38	GO:0048471	perinuclear region of cytoplasm

0.60	EC:4.1.1.17	GO:0004586
0.60	KEGG:R00670	GO:0004586

sp|P11940|PABP1_HUMAN
Polyadenylate-binding protein 1
Search

PABPC1

0.60	Polyadenylate-binding protein 1-A

0.45	GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.44	GO:0045070	positive regulation of viral genome replication
0.39	GO:0007507	heart development
0.37	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.37	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.36	GO:0048255	mRNA stabilization
0.36	GO:0031047	gene silencing by RNA
0.35	GO:0006417	regulation of translation
0.35	GO:0006397	mRNA processing
0.34	GO:0043043	peptide biosynthetic process

0.59	GO:0003723	RNA binding
0.42	GO:0008022	protein C-terminus binding
0.37	GO:0031370	eukaryotic initiation factor 4G binding
0.36	GO:0043621	protein self-association

0.48	GO:0005737	cytoplasm
0.42	GO:0071013	catalytic step 2 spliceosome
0.41	GO:0035770	ribonucleoprotein granule
0.36	GO:0005844	polysome

sp|P12004|PCNA_HUMAN
Proliferating cell nuclear antigen
Search

PCNA

0.66	Proliferating cell nuclear antigen

0.76	GO:0006275	regulation of DNA replication
0.65	GO:0006260	DNA replication
0.58	GO:0019985	translesion synthesis
0.58	GO:0032077	positive regulation of deoxyribonuclease activity
0.56	GO:0045739	positive regulation of DNA repair
0.55	GO:0034644	cellular response to UV
0.53	GO:0030855	epithelial cell differentiation
0.52	GO:0006298	mismatch repair
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process

0.84	GO:0030337	DNA polymerase processivity factor activity
0.60	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity
0.59	GO:0032405	MutLalpha complex binding
0.58	GO:0032139	dinucleotide insertion or deletion binding
0.57	GO:0070182	DNA polymerase binding
0.57	GO:0035035	histone acetyltransferase binding
0.56	GO:0030971	receptor tyrosine kinase binding
0.52	GO:0003682	chromatin binding
0.50	GO:0042802	identical protein binding
0.50	GO:0003684	damaged DNA binding

0.61	GO:0070557	PCNA-p21 complex
0.60	GO:0043626	PCNA complex
0.54	GO:0043596	nuclear replication fork
0.52	GO:0005813	centrosome
0.52	GO:0016604	nuclear body
0.38	GO:0005652	nuclear lamina
0.38	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.36	GO:0000784	nuclear chromosome, telomeric region
0.36	GO:0070062	extracellular exosome
0.35	GO:0005663	DNA replication factor C complex

0.60

EC:3.2.2

GO:0000701

sp|P12018|VPREB_HUMAN
Immunoglobulin iota chain
Search

VPREB1

0.50	Immunoglobulin omega chain

0.83	GO:0002377	immunoglobulin production
0.72	GO:0006955	immune response
0.57	GO:0042100	B cell proliferation
0.54	GO:0008361	regulation of cell size
0.53	GO:0048872	homeostasis of number of cells
0.51	GO:0000902	cell morphogenesis
0.48	GO:0030097	hemopoiesis
0.43	GO:0050900	leukocyte migration

0.43	GO:0004872	receptor activity
0.37	GO:0005515	protein binding

0.70	GO:0005615	extracellular space
0.49	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P12034|FGF5_HUMAN
Fibroblast growth factor 5
Search

FGF5

0.61	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.74	GO:0010469	regulation of receptor activity
0.62	GO:0023019	signal transduction involved in regulation of gene expression
0.58	GO:0010001	glial cell differentiation
0.57	GO:0008284	positive regulation of cell proliferation
0.45	GO:0061550	cranial ganglion development
0.42	GO:0051781	positive regulation of cell division
0.37	GO:0008283	cell proliferation
0.36	GO:0001502	cartilage condensation
0.36	GO:0051897	positive regulation of protein kinase B signaling

0.84	GO:0005104	fibroblast growth factor receptor binding
0.77	GO:0008083	growth factor activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0005163	nerve growth factor receptor binding
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.65	GO:0005576	extracellular region
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|P12035|K2C3_HUMAN
Keratin, type II cytoskeletal 3
Search

0.86	Keratin, type II cytoskeletal 2 epidermal

0.53	GO:0045103	intermediate filament-based process
0.51	GO:0009888	tissue development
0.50	GO:0043588	skin development
0.50	GO:0007010	cytoskeleton organization
0.47	GO:0043473	pigmentation
0.47	GO:0030154	cell differentiation
0.46	GO:0048732	gland development
0.44	GO:0050680	negative regulation of epithelial cell proliferation
0.41	GO:0030097	hemopoiesis
0.39	GO:0012501	programmed cell death

0.62	GO:0005198	structural molecule activity
0.37	GO:0005515	protein binding

0.83	GO:0045095	keratin filament
0.42	GO:0009986	cell surface
0.40	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.36	GO:0001533	cornified envelope
0.35	GO:0005634	nucleus

sp|P12036|NFH_HUMAN
Neurofilament heavy polypeptide
Search

NEFH

0.88	Neurofilament medium polypeptide

0.77	GO:0061564	axon development
0.64	GO:0033693	neurofilament bundle assembly
0.63	GO:1902513	regulation of organelle transport along microtubule
0.58	GO:0048935	peripheral nervous system neuron development
0.56	GO:1990830	cellular response to leukemia inhibitory factor
0.54	GO:0048812	neuron projection morphogenesis
0.54	GO:0048667	cell morphogenesis involved in neuron differentiation
0.52	GO:0000226	microtubule cytoskeleton organization
0.41	GO:0006334	nucleosome assembly
0.37	GO:1903937	response to acrylamide

0.62	GO:0005198	structural molecule activity
0.56	GO:0019901	protein kinase binding
0.39	GO:0030674	protein binding, bridging
0.37	GO:0019894	kinesin binding
0.37	GO:0070840	dynein complex binding
0.36	GO:0008017	microtubule binding
0.36	GO:0015643	toxic substance binding
0.36	GO:0003677	DNA binding
0.35	GO:0046982	protein heterodimerization activity
0.33	GO:0005219	ryanodine-sensitive calcium-release channel activity

0.85	GO:0005883	neurofilament
0.63	GO:0097418	neurofibrillary tangle
0.56	GO:0014069	postsynaptic density
0.55	GO:0043209	myelin sheath
0.54	GO:0030424	axon
0.45	GO:0005739	mitochondrion
0.40	GO:0000786	nucleosome
0.36	GO:0043204	perikaryon
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P12074|CX6A1_HUMAN
Cytochrome c oxidase subunit 6A1, mitochondrial
Search

COX6A1

0.80	Cytochrome c oxidase subunit VIa polypeptide 1

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.43	GO:0050790	regulation of catalytic activity
0.41	GO:0006119	oxidative phosphorylation
0.41	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.44	GO:0030234	enzyme regulator activity

0.83	GO:0005751	mitochondrial respiratory chain complex IV
0.36	GO:0043209	myelin sheath
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9

GO:0016675

sp|P12081|SYHC_HUMAN
Histidine--tRNA ligase, cytoplasmic
Search

HARS

0.65	Histidyl-tRNA synthetase

0.75	GO:0006427	histidyl-tRNA aminoacylation
0.48	GO:0032543	mitochondrial translation

0.75	GO:0004821	histidine-tRNA ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.41	GO:0046983	protein dimerization activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0003676	nucleic acid binding

0.49	GO:0005737	cytoplasm
0.41	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

0.75

EC:6.1.1.21

GO:0004821

sp|P12104|FABPI_HUMAN
Fatty acid-binding protein, intestinal
Search

FABP2

0.96	Intestinal fatty acid binding protein 2

0.37	GO:0007586	digestion
0.35	GO:0019433	triglyceride catabolic process
0.34	GO:0015909	long-chain fatty acid transport
0.34	GO:0003008	system process
0.33	GO:0006631	fatty acid metabolic process

0.85	GO:0005504	fatty acid binding
0.35	GO:0005324	long-chain fatty acid transporter activity
0.33	GO:0005515	protein binding

0.38	GO:0005622	intracellular
0.37	GO:0031526	brush border membrane
0.35	GO:0005902	microvillus
0.34	GO:0045177	apical part of cell
0.34	GO:0043227	membrane-bounded organelle

sp|P12107|COBA1_HUMAN
Collagen alpha-1(XI) chain
Search

COL11A1

0.71	Collagen type XI alpha 1 chain

0.59	GO:0035989	tendon development
0.57	GO:0030199	collagen fibril organization
0.56	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.55	GO:0001502	cartilage condensation
0.55	GO:0035987	endodermal cell differentiation
0.55	GO:0002063	chondrocyte development
0.54	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.53	GO:0090596	sensory organ morphogenesis
0.53	GO:0006029	proteoglycan metabolic process
0.53	GO:0048704	embryonic skeletal system morphogenesis

0.79	GO:0005201	extracellular matrix structural constituent
0.42	GO:0043394	proteoglycan binding
0.42	GO:0048407	platelet-derived growth factor binding
0.41	GO:0008201	heparin binding
0.35	GO:0050840	extracellular matrix binding
0.34	GO:0030674	protein binding, bridging
0.33	GO:0046872	metal ion binding

0.75	GO:0005581	collagen trimer
0.59	GO:0098643	banded collagen fibril
0.50	GO:0005615	extracellular space
0.39	GO:0005604	basement membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P12109|CO6A1_HUMAN
Collagen alpha-1(VI) chain
Search

COL6A1

0.95	Collagen type VI alpha 1 subunit

0.69	GO:0070208	protein heterotrimerization
0.66	GO:0035987	endodermal cell differentiation
0.65	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0001649	osteoblast differentiation
0.42	GO:0007155	cell adhesion
0.39	GO:0030574	collagen catabolic process
0.38	GO:0030198	extracellular matrix organization
0.36	GO:0006979	response to oxidative stress
0.36	GO:0098869	cellular oxidant detoxification
0.34	GO:0009749	response to glucose

0.69	GO:0048407	platelet-derived growth factor binding
0.36	GO:0004601	peroxidase activity
0.35	GO:0020037	heme binding

0.69	GO:0005581	collagen trimer
0.65	GO:0042383	sarcolemma
0.60	GO:0005578	proteinaceous extracellular matrix
0.58	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.41	GO:0005765	lysosomal membrane
0.41	GO:0098647	collagen beaded filament
0.39	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:1.11.1.7	GO:0004601
0.36	KEGG:R03532	GO:0004601

sp|P12110|CO6A2_HUMAN
Collagen alpha-2(VI) chain
Search

COL6A2

0.74	Collagen type VI alpha 2 chain

0.55	GO:0070208	protein heterotrimerization
0.36	GO:0009749	response to glucose
0.35	GO:0007155	cell adhesion
0.35	GO:0030574	collagen catabolic process
0.34	GO:0048747	muscle fiber development
0.34	GO:0030198	extracellular matrix organization
0.34	GO:0007517	muscle organ development
0.34	GO:0007409	axonogenesis

0.33

GO:0005515

protein binding

0.75	GO:0005581	collagen trimer
0.53	GO:0042383	sarcolemma
0.49	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P12111|CO6A3_HUMAN
Collagen alpha-3(VI) chain
Search

COL6A3

0.85	Collagen type VI alpha 3 chain

0.75	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0030574	collagen catabolic process
0.40	GO:0007517	muscle organ development
0.40	GO:0030198	extracellular matrix organization
0.38	GO:0007155	cell adhesion
0.34	GO:0048675	axon extension
0.34	GO:0008045	motor neuron axon guidance

0.78

GO:0004867

serine-type endopeptidase inhibitor activity

0.68	GO:0005581	collagen trimer
0.63	GO:0042383	sarcolemma
0.58	GO:0005578	proteinaceous extracellular matrix
0.56	GO:0005615	extracellular space
0.43	GO:0098647	collagen beaded filament
0.40	GO:0005788	endoplasmic reticulum lumen
0.40	GO:1903561	extracellular vesicle

sp|P12235|ADT1_HUMAN
ADP/ATP translocase 1
Search

SLC25A4

0.90	Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4

0.57	GO:0015866	ADP transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0060546	negative regulation of necroptotic process
0.54	GO:0007005	mitochondrion organization
0.53	GO:0090559	regulation of membrane permeability
0.50	GO:0006839	mitochondrial transport
0.50	GO:0015867	ATP transport
0.48	GO:0006915	apoptotic process
0.46	GO:0061024	membrane organization
0.44	GO:0010823	negative regulation of mitochondrion organization

0.57	GO:0022857	transmembrane transporter activity
0.41	GO:0031625	ubiquitin protein ligase binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.52	GO:0043209	myelin sheath
0.45	GO:0071817	MMXD complex
0.42	GO:0042645	mitochondrial nucleoid
0.38	GO:0031301	integral component of organelle membrane
0.35	GO:0031968	organelle outer membrane
0.34	GO:0045121	membrane raft
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

sp|P12236|ADT3_HUMAN
ADP/ATP translocase 3
Search

0.81	LOW QUALITY PROTEIN: ADP/ATP translocase 2

0.56	GO:0046902	regulation of mitochondrial membrane permeability
0.55	GO:0015866	ADP transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0015867	ATP transport
0.50	GO:0043069	negative regulation of programmed cell death
0.49	GO:0060547	negative regulation of necrotic cell death
0.49	GO:0060544	regulation of necroptotic process
0.48	GO:0008637	apoptotic mitochondrial changes
0.46	GO:0010823	negative regulation of mitochondrion organization
0.44	GO:2001233	regulation of apoptotic signaling pathway

0.57	GO:0022857	transmembrane transporter activity
0.43	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.33	GO:0008171	O-methyltransferase activity
0.33	GO:0003723	RNA binding

0.62	GO:0005743	mitochondrial inner membrane
0.50	GO:0043209	myelin sheath
0.47	GO:0071817	MMXD complex
0.44	GO:0042645	mitochondrial nucleoid
0.38	GO:0098857	membrane microdomain
0.37	GO:0032592	integral component of mitochondrial membrane
0.36	GO:0031012	extracellular matrix
0.35	GO:0005741	mitochondrial outer membrane
0.34	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome

0.34

EC:3.6.1.19

GO:0047429

sp|P12259|FA5_HUMAN
Coagulation factor V
Search

0.77	Coagulation factor V

0.74	GO:0007596	blood coagulation
0.62	GO:0008015	blood circulation
0.45	GO:0002576	platelet degranulation
0.44	GO:0048208	COPII vesicle coating
0.43	GO:0043687	post-translational protein modification
0.42	GO:0032571	response to vitamin K
0.40	GO:0072376	protein activation cascade
0.38	GO:0001775	cell activation
0.37	GO:0055114	oxidation-reduction process
0.32	GO:0007155	cell adhesion

0.72	GO:0005507	copper ion binding
0.38	GO:0005515	protein binding
0.37	GO:0016491	oxidoreductase activity

0.68	GO:0031091	platelet alpha granule
0.58	GO:0005615	extracellular space
0.46	GO:1903561	extracellular vesicle
0.45	GO:0034774	secretory granule lumen
0.44	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.43	GO:0005788	endoplasmic reticulum lumen
0.43	GO:0005794	Golgi apparatus
0.42	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.39	GO:0031984	organelle subcompartment
0.37	GO:0005886	plasma membrane

0.37

GO:0016491

sp|P12268|IMDH2_HUMAN
Inosine-5'-monophosphate dehydrogenase 2
Search

IMPDH2

0.53	Inosine-5'-monophosphate dehydrogenase

0.75	GO:0006177	GMP biosynthetic process
0.56	GO:0007623	circadian rhythm
0.56	GO:0071353	cellular response to interleukin-4
0.55	GO:0046651	lymphocyte proliferation
0.52	GO:0055114	oxidation-reduction process
0.47	GO:0006183	GTP biosynthetic process
0.39	GO:0051289	protein homotetramerization
0.39	GO:0001654	eye development
0.37	GO:0043312	neutrophil degranulation
0.35	GO:0048066	developmental pigmentation

0.78	GO:0003938	IMP dehydrogenase activity
0.53	GO:0046872	metal ion binding
0.49	GO:1901265	nucleoside phosphate binding
0.48	GO:0036094	small molecule binding
0.35	GO:0003723	RNA binding
0.34	GO:0003677	DNA binding
0.33	GO:0004814	arginine-tRNA ligase activity
0.33	GO:0005515	protein binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.57	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.37	GO:1904813	ficolin-1-rich granule lumen
0.37	GO:0034774	secretory granule lumen
0.36	GO:0070062	extracellular exosome
0.36	GO:0031903	microbody membrane
0.36	GO:0044439	peroxisomal part
0.35	GO:0005766	primary lysosome
0.35	GO:0005775	vacuolar lumen

0.78

EC:1.1.1.205

GO:0003938

sp|P12270|TPR_HUMAN
Nucleoprotein TPR
Search

TPR

0.94	Translocated promoter region (To activated MET oncogene)

0.81	GO:0006606	protein import into nucleus
0.77	GO:0046832	negative regulation of RNA export from nucleus
0.74	GO:0035457	cellular response to interferon-alpha
0.74	GO:0031453	positive regulation of heterochromatin assembly
0.74	GO:0031990	mRNA export from nucleus in response to heat stress
0.74	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.73	GO:0006404	RNA import into nucleus
0.72	GO:0070849	response to epidermal growth factor
0.72	GO:1901673	regulation of mitotic spindle assembly
0.72	GO:0006999	nuclear pore organization

0.73	GO:0051019	mitogen-activated protein kinase binding
0.70	GO:0070840	dynein complex binding
0.68	GO:0005487	structural constituent of nuclear pore
0.65	GO:0031072	heat shock protein binding
0.64	GO:0003682	chromatin binding
0.63	GO:0003729	mRNA binding
0.63	GO:0042803	protein homodimerization activity
0.62	GO:0015631	tubulin binding

0.73	GO:0042405	nuclear inclusion body
0.73	GO:0044615	nuclear pore nuclear basket
0.69	GO:0005868	cytoplasmic dynein complex
0.67	GO:0034399	nuclear periphery
0.67	GO:0072686	mitotic spindle
0.66	GO:0031965	nuclear membrane
0.65	GO:0000776	kinetochore
0.63	GO:0019898	extrinsic component of membrane
0.44	GO:0005737	cytoplasm

sp|P12271|RLBP1_HUMAN
Retinaldehyde-binding protein 1
Search

RLBP1

0.94	Retinaldehyde-binding protein 1

0.78	GO:0007601	visual perception
0.50	GO:0007634	optokinetic behavior
0.40	GO:0007040	lysosome organization
0.36	GO:0006776	vitamin A metabolic process

0.86	GO:0016918	retinal binding
0.40	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.40	GO:0019841	retinol binding

0.39	GO:0005802	trans-Golgi network
0.39	GO:0030136	clathrin-coated vesicle
0.39	GO:0044297	cell body
0.38	GO:0005768	endosome
0.34	GO:0005829	cytosol

sp|P12272|PTHR_HUMAN
Parathyroid hormone-related protein
Search

PTHLH

0.97	Parathyroid hormone like hormone

0.85	GO:0032330	regulation of chondrocyte differentiation
0.75	GO:0010469	regulation of receptor activity
0.61	GO:0061037	negative regulation of cartilage development
0.60	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.60	GO:0030819	positive regulation of cAMP biosynthetic process
0.56	GO:0045596	negative regulation of cell differentiation
0.56	GO:0001501	skeletal system development
0.52	GO:0002076	osteoblast development
0.44	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0042127	regulation of cell proliferation

0.79	GO:0005179	hormone activity
0.64	GO:0051428	peptide hormone receptor binding

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol

sp|P12273|PIP_HUMAN
Prolactin-inducible protein
Search

PIP

0.97	Prolactin inducted protein (Fragment)

0.73	GO:0070233	negative regulation of T cell apoptotic process
0.72	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.61	GO:0010628	positive regulation of gene expression
0.52	GO:0006508	proteolysis

0.76	GO:0019864	IgG binding
0.59	GO:0070001	aspartic-type peptidase activity
0.58	GO:0046983	protein dimerization activity
0.55	GO:0004175	endopeptidase activity

0.66	GO:0005576	extracellular region
0.53	GO:0005634	nucleus

sp|P12277|KCRB_HUMAN
Creatine kinase B-type
Search

CKB

0.91	Brain-subtype creatine kinase

0.57	GO:0016310	phosphorylation
0.44	GO:0030644	cellular chloride ion homeostasis
0.41	GO:0007420	brain development
0.39	GO:0046314	phosphocreatine biosynthetic process
0.37	GO:0009408	response to heat
0.37	GO:0048857	neural nucleus development
0.35	GO:0006600	creatine metabolic process
0.34	GO:0006754	ATP biosynthetic process

0.60	GO:0004111	creatine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031625	ubiquitin protein ligase binding

0.50	GO:0043209	myelin sheath
0.48	GO:0005615	extracellular space
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.38	GO:0043230	extracellular organelle
0.36	GO:0005634	nucleus
0.35	GO:0031982	vesicle

0.60	EC:2.7.3.2	GO:0004111
0.60	KEGG:R01881	GO:0004111

sp|P12314|FCGR1_HUMAN
High affinity immunoglobulin gamma Fc receptor I
Search

0.94	High affinity immunoglobulin gamma Fc receptor I

0.52	GO:0001788	antibody-dependent cellular cytotoxicity
0.52	GO:0038094	Fc-gamma receptor signaling pathway
0.52	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
0.52	GO:0001805	positive regulation of type III hypersensitivity
0.51	GO:0002894	positive regulation of type II hypersensitivity
0.51	GO:0001796	regulation of type IIa hypersensitivity
0.51	GO:0006911	phagocytosis, engulfment
0.50	GO:0050766	positive regulation of phagocytosis
0.49	GO:0006910	phagocytosis, recognition
0.46	GO:0009617	response to bacterium

0.53	GO:0019864	IgG binding
0.52	GO:0019770	IgG receptor activity
0.40	GO:0031774	leukotriene receptor binding
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0001540	amyloid-beta binding
0.35	GO:0042289	MHC class II protein binding
0.34	GO:0019903	protein phosphatase binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0034987	immunoglobulin receptor binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0009897	external side of plasma membrane
0.39	GO:0098805	whole membrane
0.37	GO:0045334	clathrin-coated endocytic vesicle
0.37	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005769	early endosome
0.36	GO:0044440	endosomal part
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0043197	dendritic spine
0.35	GO:0070062	extracellular exosome
0.35	GO:0044297	cell body

0.34

EC:3.1.3

GO:0008138

sp|P12318|FCG2A_HUMAN
Low affinity immunoglobulin gamma Fc region receptor II-a
Search

FCGR2A

0.96	Low affinity immunoglobulin gamma Fc region receptor II-a

0.42	GO:0038094	Fc-gamma receptor signaling pathway
0.41	GO:0002274	myeloid leukocyte activation
0.41	GO:0002443	leukocyte mediated immunity
0.40	GO:0001810	regulation of type I hypersensitivity
0.40	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
0.40	GO:0002431	Fc receptor mediated stimulatory signaling pathway
0.40	GO:0006955	immune response
0.39	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.39	GO:0050766	positive regulation of phagocytosis
0.39	GO:0006911	phagocytosis, engulfment

0.47	GO:0019864	IgG binding
0.41	GO:0019770	IgG receptor activity
0.37	GO:0001540	amyloid-beta binding
0.34	GO:0034987	immunoglobulin receptor binding
0.34	GO:0019767	IgE receptor activity
0.34	GO:0019863	IgE binding
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.38	GO:0009897	external side of plasma membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0043197	dendritic spine
0.37	GO:0030667	secretory granule membrane
0.37	GO:0044297	cell body
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0055037	recycling endosome
0.34	GO:0098857	membrane microdomain
0.33	GO:0031225	anchored component of membrane
0.33	GO:0005856	cytoskeleton

sp|P12319|FCERA_HUMAN
High affinity immunoglobulin epsilon receptor subunit alpha
Search

FCER1A

0.97	High affinity immunoglobulin epsilon receptor subunit alpha

0.50	GO:0038093	Fc receptor signaling pathway
0.47	GO:0002885	positive regulation of hypersensitivity
0.46	GO:0002888	positive regulation of myeloid leukocyte mediated immunity
0.46	GO:0002891	positive regulation of immunoglobulin mediated immune response
0.44	GO:0001788	antibody-dependent cellular cytotoxicity
0.44	GO:0001803	regulation of type III hypersensitivity
0.44	GO:0002892	regulation of type II hypersensitivity
0.43	GO:0001810	regulation of type I hypersensitivity
0.43	GO:0060627	regulation of vesicle-mediated transport
0.43	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I

0.50	GO:0019865	immunoglobulin binding
0.50	GO:0019763	immunoglobulin receptor activity
0.38	GO:0031774	leukotriene receptor binding
0.35	GO:0034987	immunoglobulin receptor binding
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0004713	protein tyrosine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0009986	cell surface
0.42	GO:0098552	side of membrane
0.40	GO:0044459	plasma membrane part
0.38	GO:0098857	membrane microdomain
0.35	GO:0005576	extracellular region
0.34	GO:0031982	vesicle
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.33

GO:0004713

sp|P12429|ANXA3_HUMAN
Annexin A3
Search

0.59

Annexin

0.61	GO:0043086	negative regulation of catalytic activity
0.59	GO:0050819	negative regulation of coagulation
0.54	GO:0006909	phagocytosis
0.54	GO:0043312	neutrophil degranulation
0.53	GO:0010595	positive regulation of endothelial cell migration
0.52	GO:0045766	positive regulation of angiogenesis
0.51	GO:0051091	positive regulation of DNA binding transcription factor activity
0.49	GO:0042742	defense response to bacterium
0.40	GO:0051592	response to calcium ion
0.40	GO:0032506	cytokinetic process

0.81	GO:0005544	calcium-dependent phospholipid binding
0.72	GO:0004859	phospholipase inhibitor activity
0.70	GO:0005509	calcium ion binding
0.55	GO:0048306	calcium-dependent protein binding
0.46	GO:0008429	phosphatidylethanolamine binding
0.43	GO:0044548	S100 protein binding
0.35	GO:0033676	double-stranded DNA-dependent ATPase activity
0.35	GO:0098641	cadherin binding involved in cell-cell adhesion
0.35	GO:0036310	annealing helicase activity
0.34	GO:0005262	calcium channel activity

0.56	GO:0042581	specific granule
0.53	GO:0045335	phagocytic vesicle
0.52	GO:0030666	endocytic vesicle membrane
0.47	GO:0005829	cytosol
0.42	GO:0072563	endothelial microparticle
0.42	GO:0030496	midbody
0.42	GO:0005886	plasma membrane
0.41	GO:0005766	primary lysosome
0.40	GO:0005819	spindle
0.40	GO:0005635	nuclear envelope

sp|P12524|MYCL_HUMAN
Protein L-Myc
Search

MYCL

0.97	MYCL proto-oncogene, bHLH transcription factor a

0.62	GO:0045607	regulation of inner ear auditory receptor cell differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.34	GO:0048712	negative regulation of astrocyte differentiation
0.34	GO:0001502	cartilage condensation
0.34	GO:0002053	positive regulation of mesenchymal cell proliferation
0.34	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.34	GO:0042733	embryonic digit morphogenesis
0.34	GO:0048704	embryonic skeletal system morphogenesis

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003677	DNA binding
0.33	GO:0019900	kinase binding
0.33	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

sp|P12525|MYCP1_HUMAN
Putative myc-like protein MYCLP1
Search

MYCL

0.97	MYCL proto-oncogene, bHLH transcription factor a

0.61	GO:0045607	regulation of inner ear auditory receptor cell differentiation
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.33	GO:0006915	apoptotic process

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003677	DNA binding

0.61

GO:0005634

nucleus

sp|P12532|KCRU_HUMAN
Creatine kinase U-type, mitochondrial
Search

0.91	Creatine kinase U-typeserine-threonine

0.57	GO:0016310	phosphorylation
0.46	GO:0032091	negative regulation of protein binding
0.44	GO:0043066	negative regulation of apoptotic process
0.38	GO:0006600	creatine metabolic process
0.36	GO:0021549	cerebellum development
0.36	GO:0007519	skeletal muscle tissue development
0.36	GO:0048565	digestive tract development
0.36	GO:0001822	kidney development
0.35	GO:0006936	muscle contraction

0.59	GO:0016301	kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.35	GO:0005515	protein binding

0.45	GO:0043209	myelin sheath
0.45	GO:0005739	mitochondrion
0.39	GO:0019866	organelle inner membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:0043204	perikaryon
0.30	GO:0044425	membrane part

0.40

EC:2.7.3

GO:0016775

sp|P12544|GRAA_HUMAN
Granzyme A
Search

GZMA

0.96	Granzyme A

0.61	GO:0006508	proteolysis
0.59	GO:0032078	negative regulation of endodeoxyribonuclease activity
0.56	GO:0051354	negative regulation of oxidoreductase activity
0.55	GO:0043392	negative regulation of DNA binding
0.52	GO:0043065	positive regulation of apoptotic process
0.49	GO:0044257	cellular protein catabolic process
0.41	GO:0008219	cell death
0.40	GO:0001909	leukocyte mediated cytotoxicity
0.40	GO:0002228	natural killer cell mediated immunity
0.39	GO:0009405	pathogenesis

0.69	GO:0004252	serine-type endopeptidase activity
0.50	GO:0042803	protein homodimerization activity
0.40	GO:0090729	toxin activity
0.35	GO:0008201	heparin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0004713	protein tyrosine kinase activity
0.32	GO:0003883	CTP synthase activity
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0020037	heme binding

0.44	GO:0005634	nucleus
0.42	GO:0030141	secretory granule
0.41	GO:0005576	extracellular region
0.36	GO:0001772	immunological synapse
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.33	GO:0042629	mast cell granule
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P12643|BMP2_HUMAN
Bone morphogenetic protein 2
Search

BMP2

0.75	Bone morphogenetic protein 2-A

0.75	GO:0010469	regulation of receptor activity
0.62	GO:0003134	endodermal-mesodermal cell signaling involved in heart induction
0.61	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development
0.61	GO:0035630	bone mineralization involved in bone maturation
0.61	GO:0051042	negative regulation of calcium-independent cell-cell adhesion
0.60	GO:2000726	negative regulation of cardiac muscle cell differentiation
0.60	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.60	GO:0060395	SMAD protein signal transduction
0.59	GO:0032345	negative regulation of aldosterone metabolic process
0.59	GO:2000065	negative regulation of cortisol biosynthetic process

0.78	GO:0008083	growth factor activity
0.61	GO:0070700	BMP receptor binding
0.58	GO:0039706	co-receptor binding
0.57	GO:0046332	SMAD binding
0.57	GO:0019211	phosphatase activator activity
0.56	GO:0004745	retinol dehydrogenase activity
0.51	GO:0046982	protein heterodimerization activity
0.48	GO:0005125	cytokine activity
0.48	GO:0005160	transforming growth factor beta receptor binding
0.34	GO:0019904	protein domain specific binding

0.66	GO:0005576	extracellular region
0.59	GO:0070724	BMP receptor complex
0.53	GO:0009986	cell surface
0.42	GO:0043227	membrane-bounded organelle
0.41	GO:0043229	intracellular organelle
0.33	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm

0.56

EC:1.1.1.105

GO:0004745

sp|P12644|BMP4_HUMAN
Bone morphogenetic protein 4
Search

BMP4

0.79	Bone morphogenetic protein 4

0.73	GO:0010469	regulation of receptor activity
0.62	GO:0071893	BMP signaling pathway involved in nephric duct formation
0.62	GO:0061155	pulmonary artery endothelial tube morphogenesis
0.62	GO:2000005	negative regulation of metanephric S-shaped body morphogenesis
0.62	GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis
0.62	GO:0055018	regulation of cardiac muscle fiber development
0.62	GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development
0.62	GO:0048392	intermediate mesodermal cell differentiation
0.61	GO:0072100	specification of ureteric bud anterior/posterior symmetry
0.61	GO:0061216	regulation of transcription from RNA polymerase II promoter involved in mesonephros development

0.75	GO:0008083	growth factor activity
0.62	GO:0070700	BMP receptor binding
0.58	GO:0039706	co-receptor binding
0.58	GO:0042056	chemoattractant activity
0.56	GO:0005125	cytokine activity
0.53	GO:0008201	heparin binding
0.46	GO:0005160	transforming growth factor beta receptor binding
0.34	GO:0042803	protein homodimerization activity

0.64	GO:0005576	extracellular region
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0031982	vesicle

sp|P12645|BMP3_HUMAN
Bone morphogenetic protein 3
Search

BMP3

0.96	Bone morphogenetic protein 3

0.74	GO:0010469	regulation of receptor activity
0.72	GO:0001649	osteoblast differentiation
0.53	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.49	GO:0060395	SMAD protein signal transduction
0.49	GO:0030509	BMP signaling pathway
0.47	GO:0043408	regulation of MAPK cascade
0.46	GO:0048856	anatomical structure development
0.45	GO:0042981	regulation of apoptotic process
0.43	GO:0045668	negative regulation of osteoblast differentiation
0.42	GO:0045444	fat cell differentiation

0.77	GO:0008083	growth factor activity
0.65	GO:0005125	cytokine activity
0.61	GO:0070700	BMP receptor binding
0.49	GO:0005160	transforming growth factor beta receptor binding
0.35	GO:0016015	morphogen activity

0.65	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|P12694|ODBA_HUMAN
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
Search

BCKDHA

0.85	Branched chain keto acid dehydrogenase E1 alpha polypeptide

0.81	GO:0009083	branched-chain amino acid catabolic process
0.53	GO:0055114	oxidation-reduction process

0.83	GO:0003826	alpha-ketoacid dehydrogenase activity
0.83	GO:0003863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity

0.83

EC:1.2.4.4

GO:0003863

sp|P12724|ECP_HUMAN
Eosinophil cationic protein
Search

0.97	Non-secretory ribonuclease

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.47	GO:0098542	defense response to other organism
0.46	GO:0002252	immune effector process
0.45	GO:0009615	response to virus
0.45	GO:1903955	positive regulation of protein targeting to mitochondrion
0.43	GO:0016070	RNA metabolic process
0.43	GO:0019730	antimicrobial humoral response
0.41	GO:0002227	innate immune response in mucosa
0.41	GO:0006935	chemotaxis
0.41	GO:0009617	response to bacterium

0.65	GO:0004519	endonuclease activity
0.51	GO:0004540	ribonuclease activity
0.51	GO:0003676	nucleic acid binding
0.42	GO:0001530	lipopolysaccharide binding

0.49	GO:0005764	lysosome
0.42	GO:0005576	extracellular region
0.39	GO:0031982	vesicle
0.39	GO:0005775	vacuolar lumen
0.37	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

sp|P12755|SKI_HUMAN
Ski oncogene
Search

SKI

0.88	Nuclear oncoprotein skia

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0010626	negative regulation of Schwann cell proliferation
0.56	GO:0032926	negative regulation of activin receptor signaling pathway
0.55	GO:0030514	negative regulation of BMP signaling pathway
0.55	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.54	GO:0045668	negative regulation of osteoblast differentiation
0.54	GO:0070207	protein homotrimerization
0.54	GO:0043388	positive regulation of DNA binding
0.54	GO:0060395	SMAD protein signal transduction
0.53	GO:0014902	myotube differentiation

0.82	GO:0046332	SMAD binding
0.56	GO:0070491	repressing transcription factor binding
0.52	GO:0019904	protein domain specific binding
0.52	GO:0003714	transcription corepressor activity
0.51	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0019901	protein kinase binding
0.44	GO:0008270	zinc ion binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0046811	histone deacetylase inhibitor activity
0.39	GO:0043565	sequence-specific DNA binding

0.53	GO:0016605	PML body
0.50	GO:0005813	centrosome
0.44	GO:0005667	transcription factor complex
0.39	GO:0017053	transcriptional repressor complex
0.34	GO:0005737	cytoplasm

sp|P12757|SKIL_HUMAN
Ski-like protein
Search

SKIL

0.87	SKI like proto-oncogene

0.84	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.77	GO:0000122	negative regulation of transcription by RNA polymerase II
0.60	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.59	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.59	GO:0070306	lens fiber cell differentiation
0.58	GO:0002260	lymphocyte homeostasis
0.57	GO:0045596	negative regulation of cell differentiation
0.56	GO:0007050	cell cycle arrest
0.56	GO:0007179	transforming growth factor beta receptor signaling pathway
0.56	GO:0001825	blastocyst formation

0.85	GO:0046332	SMAD binding
0.58	GO:0070491	repressing transcription factor binding
0.57	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0019904	protein domain specific binding
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.53	GO:0042803	protein homodimerization activity
0.39	GO:0003714	transcription corepressor activity
0.38	GO:0032403	protein complex binding
0.36	GO:0046982	protein heterodimerization activity

0.53	GO:0005667	transcription factor complex
0.51	GO:0005634	nucleus
0.39	GO:0001669	acrosomal vesicle
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.33	GO:0015630	microtubule cytoskeleton

0.34

GO:0004674

sp|P12814|ACTN1_HUMAN
Alpha-actinin-1
Search

ACTN1

0.86	Alpha-actinin-1

0.86	GO:0051764	actin crosslink formation
0.83	GO:0051017	actin filament bundle assembly
0.69	GO:0048741	skeletal muscle fiber development
0.68	GO:0045214	sarcomere organization
0.52	GO:0051639	actin filament network formation
0.52	GO:0048041	focal adhesion assembly
0.51	GO:0030220	platelet formation
0.49	GO:0051271	negative regulation of cellular component movement
0.40	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:0070527	platelet aggregation

0.78	GO:0051015	actin filament binding
0.73	GO:0017166	vinculin binding
0.70	GO:0051393	alpha-actinin binding
0.69	GO:0005509	calcium ion binding
0.63	GO:0042803	protein homodimerization activity
0.50	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.50	GO:0044325	ion channel binding
0.50	GO:0005178	integrin binding
0.47	GO:0003725	double-stranded RNA binding
0.35	GO:0019904	protein domain specific binding

0.73	GO:0030486	smooth muscle dense body
0.72	GO:0090637	inner dense plaque of desmosome
0.72	GO:0090636	outer dense plaque of desmosome
0.72	GO:1990357	terminal web
0.71	GO:0005915	zonula adherens
0.71	GO:0097433	dense body
0.70	GO:0097517	contractile actin filament bundle
0.70	GO:0042641	actomyosin
0.68	GO:0016328	lateral plasma membrane
0.67	GO:0042383	sarcolemma

sp|P12821|ACE_HUMAN
Angiotensin-converting enzyme
Search

0.39	Angiotensin-converting enzyme

0.61	GO:0006508	proteolysis
0.30	GO:0032943	mononuclear cell proliferation
0.30	GO:0031399	regulation of protein modification process
0.30	GO:0030163	protein catabolic process
0.30	GO:0051270	regulation of cellular component movement
0.30	GO:0001655	urogenital system development
0.30	GO:0002682	regulation of immune system process
0.30	GO:0002443	leukocyte mediated immunity
0.30	GO:0051239	regulation of multicellular organismal process
0.30	GO:0033036	macromolecule localization

0.84	GO:0008241	peptidyl-dipeptidase activity
0.71	GO:0004180	carboxypeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.53	GO:0046872	metal ion binding
0.30	GO:0005515	protein binding
0.30	GO:0004175	endopeptidase activity
0.30	GO:0043168	anion binding
0.30	GO:0008144	drug binding
0.30	GO:0008236	serine-type peptidase activity
0.30	GO:0016805	dipeptidase activity

0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0009986	cell surface
0.30	GO:0071944	cell periphery
0.30	GO:0005615	extracellular space
0.30	GO:0031982	vesicle
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0043230	extracellular organelle
0.30	GO:0012505	endomembrane system
0.30	GO:0098552	side of membrane
0.30	GO:0044444	cytoplasmic part

0.84

EC:3.4.15

GO:0008241

sp|P12829|MYL4_HUMAN
Myosin light chain 4
Search

MYL4

0.95	Myosin, light chain 3, alkali ventricular, skeletal, slow

0.63	GO:0002026	regulation of the force of heart contraction
0.62	GO:0060048	cardiac muscle contraction
0.52	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.52	GO:0032781	positive regulation of ATPase activity
0.51	GO:0006942	regulation of striated muscle contraction
0.38	GO:0007519	skeletal muscle tissue development
0.37	GO:0030049	muscle filament sliding
0.35	GO:0060055	angiogenesis involved in wound healing
0.35	GO:0070527	platelet aggregation
0.35	GO:0007044	cell-substrate junction assembly

0.70	GO:0005509	calcium ion binding
0.61	GO:0003785	actin monomer binding
0.50	GO:0051015	actin filament binding
0.37	GO:0032038	myosin II heavy chain binding
0.37	GO:0003774	motor activity
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0004872	receptor activity

0.61	GO:0031672	A band
0.50	GO:0031674	I band
0.42	GO:0016459	myosin complex
0.35	GO:0005829	cytosol
0.34	GO:0008305	integrin complex

sp|P12830|CADH1_HUMAN
Cadherin-1
Search

CDH1

0.95	Truncated E-cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.59	GO:0071681	cellular response to indole-3-methanol
0.58	GO:0071285	cellular response to lithium ion
0.58	GO:0051050	positive regulation of transport
0.56	GO:0060341	regulation of cellular localization
0.56	GO:0034332	adherens junction organization
0.55	GO:0022408	negative regulation of cell-cell adhesion
0.54	GO:1904589	regulation of protein import
0.54	GO:0072659	protein localization to plasma membrane
0.54	GO:0031328	positive regulation of cellular biosynthetic process

0.70	GO:0005509	calcium ion binding
0.58	GO:0045295	gamma-catenin binding
0.58	GO:0032794	GTPase activating protein binding
0.57	GO:0030506	ankyrin binding
0.55	GO:0008013	beta-catenin binding
0.54	GO:0045296	cadherin binding
0.50	GO:0042802	identical protein binding
0.38	GO:0045294	alpha-catenin binding
0.37	GO:0019903	protein phosphatase binding
0.36	GO:0019904	protein domain specific binding

0.59	GO:0005913	cell-cell adherens junction
0.58	GO:0016600	flotillin complex
0.57	GO:0016342	catenin complex
0.56	GO:0016328	lateral plasma membrane
0.54	GO:0030027	lamellipodium
0.53	GO:0030864	cortical actin cytoskeleton
0.53	GO:0043296	apical junction complex
0.53	GO:0005802	trans-Golgi network
0.53	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0009898	cytoplasmic side of plasma membrane

sp|P12838|DEF4_HUMAN
Neutrophil defensin 4
Search

0.97	Neutrophil antibiotic peptide NP-1

0.73	GO:0042742	defense response to bacterium
0.62	GO:0050832	defense response to fungus
0.59	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.56	GO:0031640	killing of cells of other organism
0.56	GO:0045087	innate immune response
0.47	GO:0010818	T cell chemotaxis
0.46	GO:1905710	positive regulation of membrane permeability
0.45	GO:0002252	immune effector process
0.44	GO:0002385	mucosal immune response
0.44	GO:0030520	intracellular estrogen receptor signaling pathway

0.55

GO:0042803

protein homodimerization activity

0.73	GO:0005615	extracellular space
0.56	GO:0005766	primary lysosome
0.53	GO:0030141	secretory granule
0.47	GO:0005796	Golgi lumen
0.46	GO:0060205	cytoplasmic vesicle lumen
0.42	GO:1903561	extracellular vesicle
0.40	GO:0005775	vacuolar lumen
0.39	GO:0031012	extracellular matrix
0.38	GO:0030133	transport vesicle

sp|P12872|MOTI_HUMAN
Promotilin
Search

MLN

0.97	Promotilin

0.76	GO:0010469	regulation of receptor activity
0.40	GO:0007267	cell-cell signaling
0.39	GO:0007186	G-protein coupled receptor signaling pathway

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P12882|MYH1_HUMAN
Myosin-1
Search

0.78	Myosin, heavy polypeptide 1, skeletal muscle, adult

0.74	GO:0007018	microtubule-based movement
0.57	GO:0006936	muscle contraction
0.55	GO:0070252	actin-mediated cell contraction
0.53	GO:0014823	response to activity
0.50	GO:0050881	musculoskeletal movement
0.45	GO:0001778	plasma membrane repair
0.41	GO:0046034	ATP metabolic process
0.38	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005516	calmodulin binding
0.42	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.49	GO:0014704	intercalated disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0005826	actomyosin contractile ring
0.40	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.42

GO:0016887

sp|P12883|MYH7_HUMAN
Myosin-7
Search

MYH7

0.90	Cardiac myosin heavy chain-alpha

0.74	GO:0007018	microtubule-based movement
0.56	GO:0030049	muscle filament sliding
0.55	GO:0007512	adult heart development
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0014887	cardiac muscle adaptation
0.54	GO:0003300	cardiac muscle hypertrophy
0.54	GO:0002026	regulation of the force of heart contraction
0.53	GO:0055008	cardiac muscle tissue morphogenesis
0.53	GO:0003229	ventricular cardiac muscle tissue development
0.53	GO:0060048	cardiac muscle contraction

0.75	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030898	actin-dependent ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.44	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.53	GO:0030016	myofibril
0.53	GO:0044449	contractile fiber part
0.53	GO:0097517	contractile actin filament bundle
0.53	GO:0042641	actomyosin
0.33	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.33

EC:3.4.23

GO:0004190

sp|P12931|SRC_HUMAN
Proto-oncogene tyrosine-protein kinase Src
Search

SRC

0.53	Neuronal proto-oncogene tyrosine-protein kinase Src

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.58	GO:0036035	osteoclast development
0.56	GO:0071801	regulation of podosome assembly
0.56	GO:0045453	bone resorption
0.56	GO:2001286	regulation of caveolin-mediated endocytosis
0.56	GO:0051902	negative regulation of mitochondrial depolarization
0.55	GO:0086098	angiotensin-activated signaling pathway involved in heart process
0.55	GO:2000394	positive regulation of lamellipodium morphogenesis
0.55	GO:0032463	negative regulation of protein homooligomerization
0.55	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0071253	connexin binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0042169	SH2 domain binding
0.53	GO:0070851	growth factor receptor binding
0.53	GO:0097110	scaffold protein binding
0.53	GO:0046875	ephrin receptor binding

0.53	GO:0002102	podosome
0.52	GO:0032587	ruffle membrane
0.52	GO:0005901	caveola
0.51	GO:0005884	actin filament
0.50	GO:0005770	late endosome
0.50	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005764	lysosome
0.46	GO:0005829	cytosol
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0031966	mitochondrial membrane

0.79	EC:2.7.10.2	GO:0004715
0.35	KEGG:R04545	GO:0046934

sp|P12955|PEPD_HUMAN
Xaa-Pro dipeptidase
Search

PEPD

0.52	Xaa-Pro dipeptidase

0.59	GO:0006508	proteolysis
0.40	GO:0030574	collagen catabolic process
0.37	GO:1990798	pancreas regeneration
0.36	GO:0031018	endocrine pancreas development
0.33	GO:0006520	cellular amino acid metabolic process

0.70	GO:0030145	manganese ion binding
0.69	GO:0004177	aminopeptidase activity
0.40	GO:0102009	proline dipeptidase activity
0.36	GO:0008237	metallopeptidase activity
0.34	GO:0004180	carboxypeptidase activity
0.33	GO:0005515	protein binding

0.48	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome

0.69

EC:3.4.11

GO:0004177

sp|P12956|XRCC6_HUMAN
X-ray repair cross-complementing protein 6
Search

XRCC6

0.82	X-ray repair cross-complementing protein 6

0.80	GO:0006303	double-strand break repair via nonhomologous end joining
0.78	GO:0000723	telomere maintenance
0.69	GO:0032508	DNA duplex unwinding
0.63	GO:0071480	cellular response to gamma radiation
0.63	GO:0051290	protein heterotetramerization
0.61	GO:0048660	regulation of smooth muscle cell proliferation
0.59	GO:0002218	activation of innate immune response
0.57	GO:0045860	positive regulation of protein kinase activity
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0045892	negative regulation of transcription, DNA-templated

0.82	GO:0042162	telomeric DNA binding
0.73	GO:0003684	damaged DNA binding
0.71	GO:0004003	ATP-dependent DNA helicase activity
0.65	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.60	GO:0008022	protein C-terminus binding
0.59	GO:0030332	cyclin binding
0.56	GO:0044212	transcription regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.52	GO:0044877	macromolecular complex binding
0.36	GO:0003723	RNA binding

0.83	GO:0043564	Ku70:Ku80 complex
0.64	GO:0070419	nonhomologous end joining complex
0.55	GO:0005667	transcription factor complex
0.54	GO:0005730	nucleolus
0.53	GO:0032993	protein-DNA complex
0.53	GO:0005654	nucleoplasm
0.48	GO:0000784	nuclear chromosome, telomeric region
0.38	GO:1904813	ficolin-1-rich granule lumen
0.37	GO:0034774	secretory granule lumen
0.35	GO:0005829	cytosol

sp|P12980|LYL1_HUMAN
Protein lyl-1
Search

LYL1

0.95	Lymphoblastic leukemia-associated hematopoiesis regulator 1

0.65	GO:0060216	definitive hemopoiesis
0.62	GO:0071695	anatomical structure maturation
0.61	GO:0001568	blood vessel development
0.61	GO:0002521	leukocyte differentiation
0.57	GO:0042113	B cell activation
0.56	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0060217	hemangioblast cell differentiation
0.51	GO:0060375	regulation of mast cell differentiation
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0060018	astrocyte fate commitment

0.68	GO:0046983	protein dimerization activity
0.54	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.51	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.48	GO:0001158	enhancer sequence-specific DNA binding
0.47	GO:0042826	histone deacetylase binding
0.47	GO:0001085	RNA polymerase II transcription factor binding
0.46	GO:0000987	proximal promoter sequence-specific DNA binding
0.45	GO:0003682	chromatin binding
0.38	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
0.36	GO:0000049	tRNA binding

0.50	GO:0033193	Lsd1/2 complex
0.46	GO:0000118	histone deacetylase complex
0.44	GO:0005667	transcription factor complex
0.44	GO:0000790	nuclear chromatin
0.30	GO:0016020	membrane

0.38

GO:0004809

sp|P13010|XRCC5_HUMAN
X-ray repair cross-complementing protein 5
Search

XRCC5

0.92	X-ray repair cross-complementing protein 5

0.78	GO:0006303	double-strand break repair via nonhomologous end joining
0.76	GO:0000723	telomere maintenance
0.68	GO:0032508	DNA duplex unwinding
0.63	GO:0006310	DNA recombination
0.60	GO:1904430	negative regulation of t-circle formation
0.59	GO:0010212	response to ionizing radiation
0.58	GO:0060218	hematopoietic stem cell differentiation
0.57	GO:0032212	positive regulation of telomere maintenance via telomerase
0.56	GO:0048660	regulation of smooth muscle cell proliferation
0.56	GO:1990823	response to leukemia inhibitory factor

0.79	GO:0042162	telomeric DNA binding
0.70	GO:0003684	damaged DNA binding
0.70	GO:0004003	ATP-dependent DNA helicase activity
0.60	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.55	GO:0008022	protein C-terminus binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.49	GO:0044877	macromolecular complex binding
0.47	GO:0030554	adenyl nucleotide binding

0.81	GO:0043564	Ku70:Ku80 complex
0.59	GO:0070419	nonhomologous end joining complex
0.56	GO:0000784	nuclear chromosome, telomeric region
0.50	GO:0032993	protein-DNA complex
0.49	GO:0005654	nucleoplasm
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.36	GO:0031983	vesicle lumen
0.36	GO:0005730	nucleolus

sp|P13051|UNG_HUMAN
Uracil-DNA glycosylase
Search

UNG

0.53	Uracil-DNA glycosylase

0.73	GO:0006284	base-excision repair
0.57	GO:0016446	somatic hypermutation of immunoglobulin genes
0.56	GO:0045830	positive regulation of isotype switching
0.56	GO:0016447	somatic recombination of immunoglobulin gene segments
0.44	GO:0070734	histone H3-K27 methylation
0.44	GO:0044030	regulation of DNA methylation
0.43	GO:0051568	histone H3-K4 methylation
0.41	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0043066	negative regulation of apoptotic process
0.37	GO:0009223	pyrimidine deoxyribonucleotide catabolic process

0.80	GO:0097506	deaminated base DNA N-glycosylase activity
0.56	GO:0043024	ribosomal small subunit binding
0.49	GO:0003684	damaged DNA binding
0.44	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity
0.33	GO:0005515	protein binding

0.56	GO:0005634	nucleus
0.56	GO:0005739	mitochondrion
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|P13056|NR2C1_HUMAN
Nuclear receptor subfamily 2 group C member 1
Search

NR2C1

0.91	Testicular nuclear receptor 2 variant 2

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.64	GO:0048386	positive regulation of retinoic acid receptor signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.52	GO:1902679	negative regulation of RNA biosynthetic process
0.50	GO:0030522	intracellular receptor signaling pathway
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0007283	spermatogenesis

0.78	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.59	GO:0042826	histone deacetylase binding
0.58	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.54	GO:0046983	protein dimerization activity
0.53	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.54	GO:0031974	membrane-enclosed lumen
0.48	GO:0044446	intracellular organelle part

sp|P13073|COX41_HUMAN
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Search

COX4I1

0.57	Mitochondrial cytochrome c oxidase subunit IV

0.61	GO:1902600	hydrogen ion transmembrane transport
0.59	GO:0022900	electron transport chain
0.42	GO:0001666	response to hypoxia
0.42	GO:0006119	oxidative phosphorylation
0.42	GO:0009060	aerobic respiration
0.40	GO:0007584	response to nutrient
0.38	GO:0036294	cellular response to decreased oxygen levels
0.35	GO:0033554	cellular response to stress
0.34	GO:0006470	protein dephosphorylation

0.63	GO:0015002	heme-copper terminal oxidase activity
0.63	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.61	GO:0015078	hydrogen ion transmembrane transporter activity
0.60	GO:0009055	electron transfer activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0005515	protein binding

0.59	GO:0005751	mitochondrial respiratory chain complex IV
0.46	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.63

EC:1.9

GO:0016675

sp|P13164|IFM1_HUMAN
Interferon-induced transmembrane protein 1
Search

0.93	Interferon-induced transmembrane protein 1

0.70	GO:0009607	response to biotic stimulus
0.46	GO:0046597	negative regulation of viral entry into host cell
0.44	GO:0035455	response to interferon-alpha
0.44	GO:0035456	response to interferon-beta
0.44	GO:0045071	negative regulation of viral genome replication
0.43	GO:0034341	response to interferon-gamma
0.41	GO:0002252	immune effector process
0.41	GO:0060337	type I interferon signaling pathway
0.40	GO:0009605	response to external stimulus
0.39	GO:0051704	multi-organism process

0.35	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0005515	protein binding

0.37	GO:0031410	cytoplasmic vesicle
0.37	GO:0005765	lysosomal membrane
0.36	GO:0012505	endomembrane system
0.36	GO:0005886	plasma membrane
0.35	GO:0045177	apical part of cell
0.35	GO:0009986	cell surface
0.34	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P13196|HEM1_HUMAN
5-aminolevulinate synthase, nonspecific, mitochondrial
Search

ALAS1

0.63	5-aminolevulinate synthase, nonspecific, mitochondrial

0.71	GO:0006782	protoporphyrinogen IX biosynthetic process
0.36	GO:0070541	response to platinum ion
0.35	GO:0032025	response to cobalt ion
0.35	GO:0034698	response to gonadotropin
0.35	GO:0051591	response to cAMP
0.35	GO:0045471	response to ethanol
0.35	GO:0010045	response to nickel cation
0.35	GO:0032869	cellular response to insulin stimulus
0.35	GO:0009635	response to herbicide
0.35	GO:0001666	response to hypoxia

0.84	GO:0003870	5-aminolevulinate synthase activity
0.67	GO:0070279	vitamin B6 binding
0.60	GO:0050662	coenzyme binding
0.53	GO:0043168	anion binding
0.50	GO:0042802	identical protein binding
0.34	GO:0016874	ligase activity

0.75	GO:0005759	mitochondrial matrix
0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

0.84	EC:2.3.1.37	GO:0003870
0.84	KEGG:R00830	GO:0003870

sp|P13224|GP1BB_HUMAN
Platelet glycoprotein Ib beta chain
Search

GP1BB

0.96	Truncated platelet membrane glycoprotein Ib beta

0.47	GO:0007596	blood coagulation
0.46	GO:0045087	innate immune response
0.44	GO:0007155	cell adhesion
0.43	GO:0007165	signal transduction
0.40	GO:0046426	negative regulation of JAK-STAT cascade
0.39	GO:0072376	protein activation cascade
0.39	GO:0006469	negative regulation of protein kinase activity
0.39	GO:0001775	cell activation
0.38	GO:0071345	cellular response to cytokine stimulus
0.37	GO:0048699	generation of neurons

0.54	GO:0042802	identical protein binding
0.39	GO:0004860	protein kinase inhibitor activity
0.37	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0035374	chondroitin sulfate binding
0.34	GO:0001968	fibronectin binding
0.34	GO:0043236	laminin binding
0.34	GO:0008201	heparin binding
0.34	GO:0005518	collagen binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0016500	protein-hormone receptor activity

0.39	GO:0031226	intrinsic component of plasma membrane
0.36	GO:0031012	extracellular matrix
0.35	GO:0005615	extracellular space
0.34	GO:0008021	synaptic vesicle
0.33	GO:0031225	anchored component of membrane
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.33

GO:0016705

sp|P13232|IL7_HUMAN
Interleukin-7
Search

IL7

0.96	Interleukin-7 variant 3

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.65	GO:0045453	bone resorption
0.65	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.64	GO:0002360	T cell lineage commitment
0.64	GO:0030890	positive regulation of B cell proliferation
0.64	GO:1901099	negative regulation of signal transduction in absence of ligand
0.63	GO:0048873	homeostasis of number of cells within a tissue
0.63	GO:0032722	positive regulation of chemokine production
0.63	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.87	GO:0005139	interleukin-7 receptor binding
0.78	GO:0008083	growth factor activity
0.72	GO:0005125	cytokine activity

0.66

GO:0005576

extracellular region

sp|P13236|CCL4_HUMAN
C-C motif chemokine 4
Search

CCL4

0.74	C-C motif chemokine

0.81	GO:0060326	cell chemotaxis
0.73	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.55	GO:0071674	mononuclear cell migration
0.55	GO:0097529	myeloid leukocyte migration
0.54	GO:0072676	lymphocyte migration
0.53	GO:0071347	cellular response to interleukin-1
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.53	GO:0006954	inflammatory response
0.53	GO:0070098	chemokine-mediated signaling pathway

0.82	GO:0008009	chemokine activity
0.56	GO:0048020	CCR chemokine receptor binding
0.46	GO:0004698	calcium-dependent protein kinase C activity
0.46	GO:0016004	phospholipase activator activity
0.45	GO:0042056	chemoattractant activity
0.41	GO:0042802	identical protein binding
0.35	GO:0046817	chemokine receptor antagonist activity
0.34	GO:0030298	receptor signaling protein tyrosine kinase activator activity
0.34	GO:0008201	heparin binding
0.34	GO:0043621	protein self-association

0.70	GO:0005615	extracellular space
0.40	GO:0005829	cytosol
0.33	GO:0015934	large ribosomal subunit
0.30	GO:0016020	membrane

0.46	EC:2.7.11	GO:0004698
0.34	KEGG:R03435	GO:0004435

sp|P13284|GILT_HUMAN
Gamma-interferon-inducible lysosomal thiol reductase
Search

IFI30

0.86	Gamma-interferon-inducible lysosomal thiol reductase

0.57	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
0.51	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.51	GO:0055114	oxidation-reduction process
0.45	GO:0048147	negative regulation of fibroblast proliferation
0.45	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.44	GO:0060333	interferon-gamma-mediated signaling pathway
0.43	GO:0050821	protein stabilization
0.42	GO:1900426	positive regulation of defense response to bacterium
0.37	GO:0016310	phosphorylation

0.66	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors
0.45	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.38	GO:0016301	kinase activity
0.38	GO:0005515	protein binding
0.36	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.74	GO:0005764	lysosome
0.70	GO:0030054	cell junction
0.65	GO:0005829	cytosol
0.47	GO:0005576	extracellular region
0.44	GO:0005942	phosphatidylinositol 3-kinase complex
0.44	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:1.8

GO:0016667

sp|P13349|MYF5_HUMAN
Myogenic factor 5
Search

MYF5

0.93	Myogenic factor

0.80	GO:0007517	muscle organ development
0.62	GO:0014706	striated muscle tissue development
0.61	GO:0001502	cartilage condensation
0.59	GO:0043010	camera-type eye development
0.59	GO:0001756	somitogenesis
0.59	GO:0001952	regulation of cell-matrix adhesion
0.58	GO:0048704	embryonic skeletal system morphogenesis
0.57	GO:0001503	ossification
0.57	GO:0006366	transcription by RNA polymerase II
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.60	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.50	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0035257	nuclear hormone receptor binding
0.41	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0003713	transcription coactivator activity
0.41	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.53	GO:0070013	intracellular organelle lumen
0.47	GO:0044446	intracellular organelle part
0.42	GO:0005667	transcription factor complex
0.42	GO:0030016	myofibril
0.39	GO:0005829	cytosol
0.39	GO:0005694	chromosome

sp|P13378|HXD8_HUMAN
Homeobox protein Hox-D8
Search

HOXB8

0.94	Homeobox protein Hox-D8

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0009653	anatomical structure morphogenesis
0.51	GO:1902679	negative regulation of RNA biosynthetic process
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:0007625	grooming behavior
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:0019233	sensory perception of pain

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

sp|P13385|TDGF1_HUMAN
Teratocarcinoma-derived growth factor 1
Search

TDGF1

0.97	Teratocarcinoma-derived growth factor

0.76	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.75	GO:0002042	cell migration involved in sprouting angiogenesis
0.75	GO:0071354	cellular response to interleukin-6
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0071364	cellular response to epidermal growth factor stimulus
0.72	GO:0071346	cellular response to interferon-gamma
0.72	GO:0010595	positive regulation of endothelial cell migration
0.71	GO:0000187	activation of MAPK activity
0.71	GO:0071356	cellular response to tumor necrosis factor
0.70	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation

0.77	GO:0008083	growth factor activity
0.44	GO:0038100	nodal binding
0.44	GO:0070698	type I activin receptor binding
0.42	GO:0017147	Wnt-protein binding
0.42	GO:0015026	coreceptor activity

0.69	GO:0016324	apical plasma membrane
0.68	GO:0098857	membrane microdomain
0.66	GO:0009986	cell surface
0.63	GO:0005615	extracellular space
0.44	GO:0019897	extrinsic component of plasma membrane
0.43	GO:0031225	anchored component of membrane
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0098552	side of membrane
0.39	GO:0005794	Golgi apparatus
0.37	GO:0005634	nucleus

sp|P13473|LAMP2_HUMAN
Lysosome-associated membrane glycoprotein 2
Search

LAMP2

0.97	Lysosome-associated membrane glycoprotein 2

0.62	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy
0.61	GO:1905146	lysosomal protein catabolic process
0.57	GO:0097352	autophagosome maturation
0.56	GO:0046716	muscle cell cellular homeostasis
0.54	GO:0031647	regulation of protein stability
0.52	GO:0009267	cellular response to starvation
0.40	GO:0032463	negative regulation of protein homooligomerization
0.37	GO:0002576	platelet degranulation
0.37	GO:0043312	neutrophil degranulation
0.36	GO:0043323	positive regulation of natural killer cell degranulation

0.51	GO:0019904	protein domain specific binding
0.51	GO:0019899	enzyme binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0004252	serine-type endopeptidase activity

0.82	GO:0005765	lysosomal membrane
0.60	GO:0031088	platelet dense granule membrane
0.59	GO:0044754	autolysosome
0.59	GO:0097636	intrinsic component of autophagosome membrane
0.57	GO:0030670	phagocytic vesicle membrane
0.56	GO:0031166	integral component of vacuolar membrane
0.56	GO:0031902	late endosome membrane
0.55	GO:0070062	extracellular exosome
0.40	GO:0043202	lysosomal lumen
0.39	GO:0048471	perinuclear region of cytoplasm

0.33

GO:0004252

sp|P13489|RINI_HUMAN
Ribonuclease inhibitor
Search

RNH1

0.74	Ribonuclease inhibitor

0.72	GO:0045765	regulation of angiogenesis
0.64	GO:0043086	negative regulation of catalytic activity
0.39	GO:0006402	mRNA catabolic process
0.38	GO:0008588	release of cytoplasmic sequestered NF-kappaB
0.38	GO:0045345	positive regulation of MHC class I biosynthetic process
0.38	GO:0045751	negative regulation of Toll signaling pathway
0.38	GO:0045409	negative regulation of interleukin-6 biosynthetic process
0.38	GO:0050711	negative regulation of interleukin-1 secretion
0.38	GO:0031953	negative regulation of protein autophosphorylation
0.37	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling

0.72	GO:0008428	ribonuclease inhibitor activity
0.39	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0016874	ligase activity

0.82	GO:0032311	angiogenin-PRI complex
0.64	GO:0005654	nucleoplasm
0.63	GO:0005829	cytosol
0.43	GO:0070062	extracellular exosome

0.32

GO:0016874

sp|P13497|BMP1_HUMAN
Bone morphogenetic protein 1
Search

BMP1

0.64	Metalloendopeptidase

0.61	GO:0006508	proteolysis
0.59	GO:0061036	positive regulation of cartilage development
0.47	GO:0048632	negative regulation of skeletal muscle tissue growth
0.39	GO:0048264	determination of ventral identity
0.39	GO:0007585	respiratory gaseous exchange
0.39	GO:0033333	fin development
0.37	GO:0036342	post-anal tail morphogenesis
0.36	GO:0001885	endothelial cell development
0.36	GO:0030513	positive regulation of BMP signaling pathway
0.36	GO:0035162	embryonic hemopoiesis

0.70	GO:0004222	metalloendopeptidase activity
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding
0.52	GO:0042802	identical protein binding

0.52	GO:0005615	extracellular space
0.35	GO:0031982	vesicle
0.30	GO:0016020	membrane

0.70

GO:0004222

sp|P13498|CY24A_HUMAN
Cytochrome b-245 light chain
Search

CYBA

0.97	Cytochrome b-245 light chain

0.61	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway
0.61	GO:0042554	superoxide anion generation
0.60	GO:0070257	positive regulation of mucus secretion
0.59	GO:0045730	respiratory burst
0.59	GO:1900426	positive regulation of defense response to bacterium
0.58	GO:0050766	positive regulation of phagocytosis
0.58	GO:1903428	positive regulation of reactive oxygen species biosynthetic process
0.58	GO:0032760	positive regulation of tumor necrosis factor production
0.58	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.57	GO:0032755	positive regulation of interleukin-6 production

0.61	GO:0020037	heme binding
0.60	GO:0016175	superoxide-generating NADPH oxidase activity
0.55	GO:0017124	SH3 domain binding
0.52	GO:0046982	protein heterodimerization activity
0.49	GO:0046872	metal ion binding
0.46	GO:0009055	electron transfer activity

0.77	GO:0043020	NADPH oxidase complex
0.52	GO:0005768	endosome
0.45	GO:0005739	mitochondrion
0.42	GO:0097038	perinuclear endoplasmic reticulum
0.41	GO:0097517	contractile actin filament bundle
0.41	GO:0042641	actomyosin
0.41	GO:0005925	focal adhesion
0.41	GO:0016324	apical plasma membrane
0.41	GO:0043025	neuronal cell body
0.40	GO:0030425	dendrite

0.60

EC:1.6.3

GO:0016175

sp|P13500|CCL2_HUMAN
C-C motif chemokine 2
Search

0.75	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.66	GO:0097529	myeloid leukocyte migration
0.61	GO:0071674	mononuclear cell migration
0.60	GO:0071347	cellular response to interleukin-1
0.59	GO:2000501	regulation of natural killer cell chemotaxis
0.59	GO:0071356	cellular response to tumor necrosis factor
0.58	GO:0006954	inflammatory response
0.56	GO:0019221	cytokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.61	GO:0048020	CCR chemokine receptor binding
0.48	GO:0016004	phospholipase activator activity
0.41	GO:0004672	protein kinase activity
0.40	GO:0008201	heparin binding
0.40	GO:0046983	protein dimerization activity
0.34	GO:0005153	interleukin-8 receptor binding

0.71	GO:0005615	extracellular space
0.36	GO:0005622	intracellular

sp|P13501|CCL5_HUMAN
C-C motif chemokine 5
Search

CCL5

0.76	C-C motif chemokine

0.81	GO:0060326	cell chemotaxis
0.81	GO:0070098	chemokine-mediated signaling pathway
0.77	GO:0006954	inflammatory response
0.74	GO:0009615	response to virus
0.73	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.65	GO:0010820	positive regulation of T cell chemotaxis
0.64	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin
0.64	GO:2000503	positive regulation of natural killer cell chemotaxis
0.64	GO:0031584	activation of phospholipase D activity

0.86	GO:0031729	CCR4 chemokine receptor binding
0.86	GO:0031726	CCR1 chemokine receptor binding
0.86	GO:0031730	CCR5 chemokine receptor binding
0.83	GO:0008009	chemokine activity
0.65	GO:0046817	chemokine receptor antagonist activity
0.63	GO:0030298	receptor signaling protein tyrosine kinase activator activity
0.63	GO:0016004	phospholipase activator activity
0.61	GO:0042056	chemoattractant activity
0.60	GO:0043621	protein self-association
0.58	GO:0004435	phosphatidylinositol phospholipase C activity

0.73	GO:0005615	extracellular space
0.39	GO:0005737	cytoplasm

0.58	EC:3.1.4.11	GO:0004435
0.58	KEGG:R03435	GO:0004435

sp|P13521|SCG2_HUMAN
Secretogranin-2
Search

SCG2

0.97	Secretogranin II

0.61	GO:0048245	eosinophil chemotaxis
0.60	GO:0050930	induction of positive chemotaxis
0.59	GO:2000352	negative regulation of endothelial cell apoptotic process
0.59	GO:0050918	positive chemotaxis
0.58	GO:0001938	positive regulation of endothelial cell proliferation
0.58	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.56	GO:0001525	angiogenesis
0.55	GO:0000165	MAPK cascade
0.53	GO:0010469	regulation of receptor activity
0.37	GO:0001937	negative regulation of endothelial cell proliferation

0.60	GO:0042056	chemoattractant activity
0.55	GO:0005125	cytokine activity

0.81	GO:0030141	secretory granule
0.52	GO:0005615	extracellular space
0.51	GO:0097458	neuron part
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0030117	membrane coat
0.34	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

sp|P13533|MYH6_HUMAN
Myosin-6
Search

MYH7

0.89	Cardiac myosin heavy chain-alpha

0.74	GO:0007018	microtubule-based movement
0.56	GO:0030049	muscle filament sliding
0.55	GO:0007512	adult heart development
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0014887	cardiac muscle adaptation
0.54	GO:0003300	cardiac muscle hypertrophy
0.54	GO:0002026	regulation of the force of heart contraction
0.54	GO:0048738	cardiac muscle tissue development
0.53	GO:0060415	muscle tissue morphogenesis
0.53	GO:0060048	cardiac muscle contraction

0.76	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030898	actin-dependent ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.44	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.53	GO:0030016	myofibril
0.53	GO:0097517	contractile actin filament bundle
0.53	GO:0044449	contractile fiber part
0.53	GO:0042641	actomyosin
0.34	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.33

EC:3.4.23

GO:0004190

sp|P13535|MYH8_HUMAN
Myosin-8
Search

0.78	Myosin, heavy polypeptide 8, skeletal muscle, perinatal

0.74	GO:0007018	microtubule-based movement
0.57	GO:0006936	muscle contraction
0.55	GO:0070252	actin-mediated cell contraction
0.53	GO:0014823	response to activity
0.50	GO:0050881	musculoskeletal movement
0.45	GO:0001778	plasma membrane repair
0.42	GO:0046034	ATP metabolic process
0.39	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0000146	microfilament motor activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005516	calmodulin binding
0.42	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.49	GO:0014704	intercalated disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0005826	actomyosin contractile ring
0.41	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.42

GO:0016887

sp|P13569|CFTR_HUMAN
Cystic fibrosis transmembrane conductance regulator
Search

CFTR

0.93	Cystic fibrosis transmembrane conductance regulator

0.76	GO:1902476	chloride transmembrane transport
0.71	GO:0035377	transepithelial water transport
0.70	GO:0060081	membrane hyperpolarization
0.70	GO:0045852	pH elevation
0.69	GO:1904322	cellular response to forskolin
0.69	GO:0048240	sperm capacitation
0.68	GO:0015701	bicarbonate transport
0.68	GO:0071320	cellular response to cAMP
0.67	GO:0050891	multicellular organismal water homeostasis
0.65	GO:0051453	regulation of intracellular pH

0.86	GO:0005260	intracellularly ATP-gated chloride channel activity
0.69	GO:0019869	chloride channel inhibitor activity
0.69	GO:0015106	bicarbonate transmembrane transporter activity
0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.54	GO:0030165	PDZ domain binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.48	GO:0019899	enzyme binding

0.81	GO:0034707	chloride channel complex
0.64	GO:0016324	apical plasma membrane
0.64	GO:0055037	recycling endosome
0.62	GO:0005769	early endosome
0.57	GO:0005789	endoplasmic reticulum membrane
0.56	GO:0098588	bounding membrane of organelle
0.56	GO:0044440	endosomal part
0.54	GO:0005887	integral component of plasma membrane
0.53	GO:0005791	rough endoplasmic reticulum
0.52	GO:0098805	whole membrane

0.86

EC:3.6.3.49

GO:0005260

sp|P13584|CP4B1_HUMAN
Cytochrome P450 4B1
Search

CYP4B1

0.97	Cytochrome P450 family 4 subfamily B polypeptide 1

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0018917	fluorene metabolic process
0.42	GO:0018879	biphenyl metabolic process
0.41	GO:0042738	exogenous drug catabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.63	GO:0020037	heme binding
0.63	GO:0004497	monooxygenase activity
0.63	GO:0005506	iron ion binding
0.40	GO:0015643	toxic substance binding
0.35	GO:0019825	oxygen binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P13591|NCAM1_HUMAN
Neural cell adhesion molecule 1
Search

NCAM1

0.91	Neural cell adhesion molecule 1

0.71	GO:0007155	cell adhesion
0.38	GO:0001928	regulation of exocyst assembly
0.37	GO:0031175	neuron projection development
0.37	GO:0050850	positive regulation of calcium-mediated signaling
0.36	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0010288	response to lead ion
0.35	GO:0021794	thalamus development
0.35	GO:0051930	regulation of sensory perception of pain
0.35	GO:0010033	response to organic substance
0.35	GO:0060045	positive regulation of cardiac muscle cell proliferation

0.37	GO:0042802	identical protein binding
0.36	GO:0008201	heparin binding
0.35	GO:0104005	hijacked molecular function
0.35	GO:0030275	LRR domain binding
0.35	GO:0019899	enzyme binding
0.35	GO:0005104	fibroblast growth factor receptor binding
0.34	GO:0008092	cytoskeletal protein binding
0.34	GO:0098772	molecular function regulator

0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0009986	cell surface
0.37	GO:0098552	side of membrane
0.37	GO:0031012	extracellular matrix
0.37	GO:0030426	growth cone
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.36	GO:0043025	neuronal cell body
0.36	GO:0030424	axon

sp|P13598|ICAM2_HUMAN
Intercellular adhesion molecule 2
Search

ICAM2

0.97	Testicular cell adhesion molecule 1

0.77	GO:0098609	cell-cell adhesion
0.41	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.39	GO:0030198	extracellular matrix organization

0.67

GO:0005178

integrin binding

0.67	GO:0001931	uropod
0.66	GO:0097610	cell surface furrow
0.64	GO:0005902	microvillus
0.63	GO:0032155	cell division site part
0.54	GO:0005887	integral component of plasma membrane
0.41	GO:0070062	extracellular exosome

sp|P13611|CSPG2_HUMAN
Versican core protein
Search

VCAN

0.74

Versican

0.69	GO:0007155	cell adhesion
0.48	GO:0001501	skeletal system development
0.47	GO:0007417	central nervous system development
0.36	GO:0035775	pronephric glomerulus morphogenesis
0.36	GO:0003093	regulation of glomerular filtration
0.36	GO:0001957	intramembranous ossification
0.36	GO:0003203	endocardial cushion morphogenesis
0.30	GO:0043687	post-translational protein modification
0.30	GO:0030166	proteoglycan biosynthetic process
0.30	GO:0019752	carboxylic acid metabolic process

0.81	GO:0005540	hyaluronic acid binding
0.69	GO:0005509	calcium ion binding
0.48	GO:0005201	extracellular matrix structural constituent
0.35	GO:0030246	carbohydrate binding
0.30	GO:0005515	protein binding

0.61	GO:0031012	extracellular matrix
0.59	GO:0005615	extracellular space
0.30	GO:0016020	membrane
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044422	organelle part
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0012505	endomembrane system
0.30	GO:0005737	cytoplasm

sp|P13612|ITA4_HUMAN
Integrin alpha-4
Search

ITGA4

0.93	Integrin subunit alpha 4

0.79	GO:0007229	integrin-mediated signaling pathway
0.71	GO:0007155	cell adhesion
0.67	GO:0090074	negative regulation of protein homodimerization activity
0.65	GO:0045123	cellular extravasation
0.64	GO:0043113	receptor clustering
0.63	GO:0035987	endodermal cell differentiation
0.61	GO:0001667	ameboidal-type cell migration
0.59	GO:0000904	cell morphogenesis involved in differentiation
0.44	GO:1990771	clathrin-dependent extracellular exosome endocytosis
0.43	GO:1903238	positive regulation of leukocyte tethering or rolling

0.67	GO:0019960	C-X3-C chemokine binding
0.60	GO:0050839	cell adhesion molecule binding
0.43	GO:0001968	fibronectin binding
0.43	GO:1990405	protein antigen binding
0.37	GO:0015026	coreceptor activity
0.35	GO:0046872	metal ion binding

0.79	GO:0008305	integrin complex
0.57	GO:0009986	cell surface
0.40	GO:0070062	extracellular exosome
0.39	GO:0030054	cell junction
0.37	GO:0098552	side of membrane

sp|P13631|RARG_HUMAN
Retinoic acid receptor gamma
Search

RARG

0.94	Retinoic acid receptor gamma-B

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0003406	retinal pigment epithelium development
0.56	GO:0003430	growth plate cartilage chondrocyte growth
0.55	GO:0070384	Harderian gland development
0.55	GO:0061037	negative regulation of cartilage development

0.86	GO:0003708	retinoic acid receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.55	GO:0046965	retinoid X receptor binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.36	GO:0001972	retinoic acid binding
0.35	GO:0005503	all-trans retinal binding
0.35	GO:0019841	retinol binding

0.61	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.47	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.34	GO:0008305	integrin complex
0.34	GO:0005829	cytosol
0.33	GO:0043025	neuronal cell body
0.33	GO:0030425	dendrite
0.33	GO:0015629	actin cytoskeleton

sp|P13637|AT1A3_HUMAN
Sodium/potassium-transporting ATPase subunit alpha-3
Search

ATP1A3

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.76	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.56	GO:0006883	cellular sodium ion homeostasis
0.55	GO:0007626	locomotory behavior
0.54	GO:0008542	visual learning
0.53	GO:0030007	cellular potassium ion homeostasis
0.53	GO:0140115	export across plasma membrane
0.53	GO:0086036	regulation of cardiac muscle cell membrane potential

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.50	GO:0051087	chaperone binding
0.50	GO:0001540	amyloid-beta binding
0.46	GO:1990239	steroid hormone binding
0.45	GO:1901681	sulfur compound binding

0.54	GO:0005890	sodium:potassium-exchanging ATPase complex
0.54	GO:0042383	sarcolemma
0.53	GO:0043209	myelin sheath
0.48	GO:0036477	somatodendritic compartment
0.48	GO:0044297	cell body
0.48	GO:0043005	neuron projection
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.41	GO:0005634	nucleus
0.41	GO:0045202	synapse

0.85

GO:0005391

sp|P13639|EF2_HUMAN
Elongation factor 2
Search

EEF2

0.56	Eukaryotic translation elongation factor 2

0.65	GO:0006414	translational elongation
0.50	GO:0002244	hematopoietic progenitor cell differentiation
0.48	GO:0045727	positive regulation of translation
0.40	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.40	GO:0051593	response to folic acid
0.40	GO:0014009	glial cell proliferation
0.40	GO:0002931	response to ischemia
0.40	GO:0003009	skeletal muscle contraction
0.39	GO:0032355	response to estradiol
0.39	GO:0035914	skeletal muscle cell differentiation

0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.64	GO:0003746	translation elongation factor activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0045296	cadherin binding
0.48	GO:0019901	protein kinase binding
0.39	GO:0002039	p53 binding
0.38	GO:0008097	5S rRNA binding

0.51	GO:0016235	aggresome
0.49	GO:0005844	polysome
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.38	GO:0045121	membrane raft
0.38	GO:0005634	nucleus
0.37	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen

sp|P13640|MT1G_HUMAN
Metallothionein-1G
Search

0.75	Metallothionein-I, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.56	GO:0045926	negative regulation of growth
0.48	GO:0036018	cellular response to erythropoietin
0.48	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.41	GO:0035690	cellular response to drug
0.40	GO:0046688	response to copper ion
0.39	GO:0007263	nitric oxide mediated signal transduction
0.38	GO:0097501	stress response to metal ion
0.38	GO:0006882	cellular zinc ion homeostasis

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.54	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.35	GO:0005829	cytosol

sp|P13645|K1C10_HUMAN
Keratin, type I cytoskeletal 10
Search

0.89	Keratin 10 (Epidermolytic hyperkeratosis; keratosis palmaris et plantaris)

0.55	GO:0030216	keratinocyte differentiation
0.53	GO:0018149	peptide cross-linking
0.41	GO:0007010	cytoskeleton organization
0.40	GO:0045103	intermediate filament-based process
0.38	GO:0071277	cellular response to calcium ion
0.37	GO:0042633	hair cycle
0.37	GO:0002064	epithelial cell development
0.37	GO:0097435	supramolecular fiber organization
0.36	GO:0012501	programmed cell death
0.36	GO:0002009	morphogenesis of an epithelium

0.62	GO:0005198	structural molecule activity
0.36	GO:0005515	protein binding
0.35	GO:0032395	MHC class II receptor activity

0.79	GO:0005882	intermediate filament
0.54	GO:0001533	cornified envelope
0.39	GO:0070062	extracellular exosome
0.38	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus

sp|P13646|K1C13_HUMAN
Keratin, type I cytoskeletal 13
Search

KRT13

0.90	Keratin, type I cytoskeletal 13

0.49	GO:0007010	cytoskeleton organization
0.42	GO:0048513	animal organ development
0.41	GO:0009653	anatomical structure morphogenesis
0.41	GO:0043627	response to estrogen
0.41	GO:0030154	cell differentiation
0.39	GO:0061061	muscle structure development
0.39	GO:0097435	supramolecular fiber organization
0.39	GO:0001701	in utero embryonic development
0.39	GO:0007219	Notch signaling pathway
0.39	GO:0008544	epidermis development

0.62	GO:0005198	structural molecule activity
0.49	GO:0097110	scaffold protein binding
0.36	GO:0032403	protein complex binding
0.33	GO:0008092	cytoskeletal protein binding

0.79	GO:0005882	intermediate filament
0.41	GO:0043034	costamere
0.41	GO:1990357	terminal web
0.40	GO:0016327	apicolateral plasma membrane
0.40	GO:0070062	extracellular exosome
0.40	GO:0042383	sarcolemma
0.40	GO:0030018	Z disc
0.36	GO:0005634	nucleus
0.35	GO:0016010	dystrophin-associated glycoprotein complex
0.35	GO:0005829	cytosol

sp|P13647|K2C5_HUMAN
Keratin, type II cytoskeletal 5
Search

KRT5

0.93	Keratin, type II cytoskeletal 5

0.47	GO:0002244	hematopoietic progenitor cell differentiation
0.42	GO:0031424	keratinization
0.38	GO:0012501	programmed cell death
0.38	GO:0007010	cytoskeleton organization
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0051803	negative regulation of cytolysis in other organism involved in symbiotic interaction
0.38	GO:0001898	regulation of cytolysis by symbiont of host cells
0.37	GO:0045103	intermediate filament-based process
0.37	GO:0050830	defense response to Gram-positive bacterium
0.37	GO:2000536	negative regulation of entry of bacterium into host cell

0.62	GO:0005198	structural molecule activity
0.53	GO:0097110	scaffold protein binding

0.83	GO:0045095	keratin filament
0.42	GO:0005739	mitochondrion
0.40	GO:0070062	extracellular exosome
0.40	GO:0005886	plasma membrane
0.37	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.33	GO:0036338	viral membrane

sp|P13667|PDIA4_HUMAN
Protein disulfide-isomerase A4
Search

PDIA4

0.83	Protein disulfide-isomerase A4

0.69	GO:0045454	cell redox homeostasis
0.53	GO:0034976	response to endoplasmic reticulum stress
0.48	GO:0006457	protein folding
0.40	GO:0055114	oxidation-reduction process
0.30	GO:0051234	establishment of localization
0.30	GO:0008104	protein localization

0.81	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds
0.57	GO:0140096	catalytic activity, acting on a protein
0.52	GO:0015037	peptide disulfide oxidoreductase activity
0.30	GO:0005515	protein binding
0.30	GO:0003676	nucleic acid binding

0.81	GO:0005788	endoplasmic reticulum lumen
0.49	GO:0009986	cell surface
0.48	GO:0005615	extracellular space
0.30	GO:0048770	pigment granule

0.81

EC:5.3.4

GO:0016864

sp|P13671|CO6_HUMAN
Complement component C6
Search

0.97	Complement component 6

0.83	GO:0006956	complement activation
0.65	GO:0001970	positive regulation of activation of membrane attack complex
0.59	GO:0045766	positive regulation of angiogenesis
0.56	GO:0001701	in utero embryonic development
0.44	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.42	GO:0045087	innate immune response
0.42	GO:0019835	cytolysis
0.35	GO:0043065	positive regulation of apoptotic process
0.33	GO:0016310	phosphorylation

0.34	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.85	GO:0005579	membrane attack complex
0.39	GO:0005576	extracellular region
0.37	GO:0031982	vesicle

sp|P13674|P4HA1_HUMAN
Prolyl 4-hydroxylase subunit alpha-1
Search

P4HA1

0.83	Procollagen-proline 2-oxoglutarate-4-dioxygenase

0.84	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0019471	4-hydroxyproline metabolic process
0.48	GO:0030199	collagen fibril organization
0.34	GO:0050482	arachidonic acid secretion
0.33	GO:0016042	lipid catabolic process
0.33	GO:0006644	phospholipid metabolic process

0.85	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.48	GO:0042802	identical protein binding
0.34	GO:0004623	phospholipase A2 activity
0.33	GO:0005509	calcium ion binding

0.70	GO:0005783	endoplasmic reticulum
0.43	GO:0005739	mitochondrion
0.42	GO:1990204	oxidoreductase complex
0.39	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen
0.36	GO:0005581	collagen trimer
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.85	EC:1.14.11.2	GO:0004656
0.85	KEGG:R03219	GO:0004656

sp|P13682|ZNF35_HUMAN
Zinc finger protein 35
Search

ZNF527

0.40	zinc finger protein 35

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.30	GO:0071396	cellular response to lipid
0.30	GO:0048232	male gamete generation
0.30	GO:0001101	response to acid chemical
0.30	GO:1901701	cellular response to oxygen-containing compound

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity

0.43	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|P13686|PPA5_HUMAN
Tartrate-resistant acid phosphatase type 5
Search

ACP5

0.91	Tartrate-resistant acid phosphatase type 5

0.61	GO:0016311	dephosphorylation
0.58	GO:0032929	negative regulation of superoxide anion generation
0.57	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.57	GO:0032691	negative regulation of interleukin-1 beta production
0.57	GO:0032695	negative regulation of interleukin-12 production
0.56	GO:0045453	bone resorption
0.55	GO:0032720	negative regulation of tumor necrosis factor production
0.54	GO:0060349	bone morphogenesis
0.54	GO:0050728	negative regulation of inflammatory response
0.54	GO:0050830	defense response to Gram-positive bacterium

0.69	GO:0003993	acid phosphatase activity
0.59	GO:0008198	ferrous iron binding
0.57	GO:0008199	ferric iron binding
0.33	GO:0003723	RNA binding

0.52	GO:0005764	lysosome
0.38	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.69

EC:3.1.3.2

GO:0003993

sp|P13688|CEAM1_HUMAN
Carcinoembryonic antigen-related cell adhesion molecule 1
Search

0.83	Pregnancy-specific beta-1-glycoprotein 5

0.51	GO:0043317	regulation of cytotoxic T cell degranulation
0.50	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.50	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.49	GO:0043301	negative regulation of leukocyte degranulation
0.48	GO:0050860	negative regulation of T cell receptor signaling pathway
0.48	GO:0090505	epiboly involved in wound healing
0.47	GO:0016477	cell migration
0.47	GO:0030334	regulation of cell migration
0.47	GO:0050868	negative regulation of T cell activation
0.44	GO:0007565	female pregnancy

0.50	GO:0031005	filamin binding
0.48	GO:1990782	protein tyrosine kinase binding
0.48	GO:0019903	protein phosphatase binding
0.46	GO:0042803	protein homodimerization activity
0.44	GO:0003779	actin binding
0.43	GO:0015125	bile acid transmembrane transporter activity
0.40	GO:0005516	calmodulin binding
0.38	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.38	GO:0034235	GPI anchor binding
0.38	GO:0046790	virion binding

0.49	GO:0042101	T cell receptor complex
0.46	GO:0009986	cell surface
0.45	GO:0005911	cell-cell junction
0.44	GO:0005615	extracellular space
0.43	GO:0016323	basolateral plasma membrane
0.43	GO:0031528	microvillus membrane
0.42	GO:0030667	secretory granule membrane
0.42	GO:0045178	basal part of cell
0.42	GO:0016328	lateral plasma membrane
0.41	GO:0042581	specific granule

sp|P13693|TCTP_HUMAN
Translationally-controlled tumor protein
Search

TPT1

0.74	Translationally-controlled tumor

0.71	GO:2000384	negative regulation of ectoderm development
0.64	GO:0019827	stem cell population maintenance
0.57	GO:0030154	cell differentiation
0.46	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.41	GO:0007283	spermatogenesis
0.41	GO:0009615	response to virus
0.39	GO:1903575	cornified envelope assembly
0.38	GO:0006874	cellular calcium ion homeostasis
0.38	GO:0008283	cell proliferation
0.38	GO:0006816	calcium ion transport

0.59	GO:0008017	microtubule binding
0.57	GO:0005509	calcium ion binding
0.57	GO:0008134	transcription factor binding
0.38	GO:0003723	RNA binding
0.37	GO:0051082	unfolded protein binding
0.35	GO:0008270	zinc ion binding

0.61	GO:0005615	extracellular space
0.58	GO:0005829	cytosol
0.57	GO:0045298	tubulin complex
0.55	GO:0005654	nucleoplasm
0.55	GO:0005771	multivesicular body
0.43	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

sp|P13716|HEM2_HUMAN
Delta-aminolevulinic acid dehydratase
Search

ALAD

0.50	Delta-aminolevulinic acid dehydratase

0.70	GO:0006779	porphyrin-containing compound biosynthetic process
0.57	GO:0071353	cellular response to interleukin-4
0.56	GO:1901799	negative regulation of proteasomal protein catabolic process
0.53	GO:0051260	protein homooligomerization
0.52	GO:0042168	heme metabolic process
0.51	GO:0046148	pigment biosynthetic process
0.42	GO:0070541	response to platinum ion
0.41	GO:0071284	cellular response to lead ion
0.41	GO:0010266	response to vitamin B1
0.41	GO:0033197	response to vitamin E

0.79	GO:0004655	porphobilinogen synthase activity
0.53	GO:0046872	metal ion binding
0.51	GO:0042802	identical protein binding
0.41	GO:1904854	proteasome core complex binding

0.43	GO:0005829	cytosol
0.38	GO:0005839	proteasome core complex
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:4.2.1.24	GO:0004655
0.79	KEGG:R00036	GO:0004655

sp|P13725|ONCM_HUMAN
Oncostatin-M
Search

OSM

0.97	Oncostatin-M

0.79	GO:0038165	oncostatin-M-mediated signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0046888	negative regulation of hormone secretion
0.74	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.74	GO:0006955	immune response
0.73	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.68	GO:0043410	positive regulation of MAPK cascade
0.68	GO:0008284	positive regulation of cell proliferation
0.65	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0008285	negative regulation of cell proliferation

0.82	GO:0005147	oncostatin-M receptor binding
0.81	GO:0005125	cytokine activity
0.67	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.33	GO:0005622	intracellular

sp|P13726|TF_HUMAN
Tissue factor
Search

0.97	Coagulation factor III, tissue factor

0.82	GO:0007596	blood coagulation
0.80	GO:0002541	activation of plasma proteins involved in acute inflammatory response
0.78	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.73	GO:0001938	positive regulation of endothelial cell proliferation
0.72	GO:0051897	positive regulation of protein kinase B signaling
0.72	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.71	GO:0045766	positive regulation of angiogenesis
0.51	GO:0019221	cytokine-mediated signaling pathway
0.41	GO:0002543	activation of blood coagulation via clotting cascade
0.41	GO:0030335	positive regulation of cell migration

0.68	GO:0002020	protease binding
0.64	GO:0005543	phospholipid binding
0.57	GO:0004252	serine-type endopeptidase activity
0.52	GO:0004896	cytokine receptor activity

0.74	GO:1905286	serine-type peptidase complex
0.65	GO:0009986	cell surface
0.64	GO:0031012	extracellular matrix
0.63	GO:0005615	extracellular space
0.41	GO:0005886	plasma membrane
0.41	GO:1903561	extracellular vesicle
0.38	GO:0098552	side of membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.57

GO:0004252

sp|P13727|PRG2_HUMAN
Bone marrow proteoglycan
Search

0.97	Eosinophil granule major basic protein 1

0.77	GO:0001819	positive regulation of cytokine production
0.75	GO:0002215	defense response to nematode
0.74	GO:0006955	immune response
0.73	GO:0032693	negative regulation of interleukin-10 production
0.72	GO:0032673	regulation of interleukin-4 production
0.68	GO:0045575	basophil activation
0.68	GO:0001694	histamine biosynthetic process
0.66	GO:0042035	regulation of cytokine biosynthetic process
0.65	GO:0019370	leukotriene biosynthetic process
0.64	GO:0042554	superoxide anion generation

0.39

GO:0030246

carbohydrate binding

sp|P13747|HLAE_HUMAN
HLA class I histocompatibility antigen, alpha chain E
Search

0.40	Patr class I histocompatibility antigen, alpha chain E

0.71	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.65	GO:0006955	immune response
0.36	GO:0032759	positive regulation of TRAIL production
0.36	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib
0.36	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation
0.36	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.36	GO:0051024	positive regulation of immunoglobulin secretion
0.36	GO:0036037	CD8-positive, alpha-beta T cell activation
0.36	GO:0032736	positive regulation of interleukin-13 production
0.36	GO:0001916	positive regulation of T cell mediated cytotoxicity

0.43	GO:0042605	peptide antigen binding
0.40	GO:0005102	receptor binding
0.36	GO:0030881	beta-2-microglobulin binding
0.34	GO:0032403	protein complex binding

0.70	GO:0042612	MHC class I protein complex
0.36	GO:0032398	MHC class Ib protein complex
0.36	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.36	GO:0030670	phagocytic vesicle membrane
0.35	GO:0055038	recycling endosome membrane
0.35	GO:0031901	early endosome membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0012507	ER to Golgi transport vesicle membrane
0.34	GO:0009986	cell surface
0.34	GO:0000139	Golgi membrane

sp|P13762|DRB4_HUMAN
HLA class II histocompatibility antigen, DR beta 4 chain
Search

0.55	HLA class II histocompatibility antigen, DR beta 4 chain

0.83	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.74	GO:0006955	immune response
0.60	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.60	GO:0031295	T cell costimulation
0.59	GO:0050852	T cell receptor signaling pathway
0.55	GO:0019221	cytokine-mediated signaling pathway
0.51	GO:0006952	defense response

0.76	GO:0042613	MHC class II protein complex
0.60	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.59	GO:0032588	trans-Golgi network membrane
0.58	GO:0030669	clathrin-coated endocytic vesicle membrane
0.57	GO:0031902	late endosome membrane
0.56	GO:0005765	lysosomal membrane
0.56	GO:0012507	ER to Golgi transport vesicle membrane

sp|P13765|DOB_HUMAN
HLA class II histocompatibility antigen, DO beta chain
Search

0.40	Major histocompatibility complex class II antigen DQB

0.77	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.52	GO:0002577	regulation of antigen processing and presentation
0.48	GO:0002683	negative regulation of immune system process
0.44	GO:0048002	antigen processing and presentation of peptide antigen
0.42	GO:0019884	antigen processing and presentation of exogenous antigen
0.41	GO:0019883	antigen processing and presentation of endogenous antigen
0.41	GO:0002377	immunoglobulin production
0.40	GO:0002449	lymphocyte mediated immunity
0.38	GO:0002343	peripheral B cell selection

0.57	GO:0023026	MHC class II protein complex binding
0.41	GO:0042605	peptide antigen binding
0.41	GO:0042287	MHC protein binding
0.41	GO:0015440	peptide-transporting ATPase activity
0.38	GO:1990405	protein antigen binding
0.37	GO:0032395	MHC class II receptor activity
0.36	GO:0015643	toxic substance binding
0.36	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0008134	transcription factor binding
0.35	GO:0032559	adenyl ribonucleotide binding

0.75	GO:0042613	MHC class II protein complex
0.51	GO:0005764	lysosome
0.41	GO:0042825	TAP complex
0.41	GO:0005771	multivesicular body
0.40	GO:0009897	external side of plasma membrane
0.40	GO:0005769	early endosome
0.38	GO:0005794	Golgi apparatus
0.37	GO:0098852	lytic vacuole membrane
0.37	GO:0010008	endosome membrane
0.34	GO:0016607	nuclear speck

0.41

EC:3.6.3.43

GO:0015440

sp|P13796|PLSL_HUMAN
Plastin-2
Search

LCP1

0.93	Lymphocyte cytosolic protein 1

0.57	GO:0051017	actin filament bundle assembly
0.56	GO:0071803	positive regulation of podosome assembly
0.56	GO:0010737	protein kinase A signaling
0.56	GO:0022617	extracellular matrix disassembly
0.55	GO:0002286	T cell activation involved in immune response
0.53	GO:0033157	regulation of intracellular protein transport
0.52	GO:0051639	actin filament network formation
0.52	GO:0051764	actin crosslink formation
0.51	GO:0016477	cell migration
0.46	GO:0060348	bone development

0.74	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.54	GO:0005178	integrin binding
0.49	GO:0051020	GTPase binding
0.49	GO:0042802	identical protein binding
0.35	GO:0004181	metallocarboxypeptidase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0004386	helicase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding

0.57	GO:0032432	actin filament bundle
0.57	GO:0005884	actin filament
0.55	GO:0002102	podosome
0.55	GO:0001891	phagocytic cup
0.54	GO:0042641	actomyosin
0.54	GO:0030175	filopodium
0.54	GO:0001726	ruffle
0.52	GO:0005925	focal adhesion
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005829	cytosol

0.35

GO:0004181

sp|P13797|PLST_HUMAN
Plastin-3
Search

PLS3

0.95

T-plastin

0.54	GO:0001501	skeletal system development
0.51	GO:0048513	animal organ development
0.49	GO:0051639	actin filament network formation
0.49	GO:0051764	actin crosslink formation
0.47	GO:0051017	actin filament bundle assembly
0.43	GO:0008045	motor neuron axon guidance
0.42	GO:1904888	cranial skeletal system development
0.42	GO:0001503	ossification
0.41	GO:0043009	chordate embryonic development
0.41	GO:0048598	embryonic morphogenesis

0.74	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.45	GO:0032403	protein complex binding
0.36	GO:0050839	cell adhesion molecule binding
0.36	GO:0051020	GTPase binding
0.36	GO:0042802	identical protein binding
0.35	GO:0005102	receptor binding

0.48	GO:0032432	actin filament bundle
0.47	GO:0005884	actin filament
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.38	GO:0098858	actin-based cell projection
0.37	GO:0002102	podosome
0.37	GO:0042641	actomyosin
0.37	GO:0001726	ruffle
0.37	GO:0005925	focal adhesion
0.36	GO:0048471	perinuclear region of cytoplasm

sp|P13798|ACPH_HUMAN
Acylamino-acid-releasing enzyme
Search

APEH

0.81	N-acylaminoacyl-peptide hydrolase

0.60	GO:0006508	proteolysis
0.59	GO:0050435	amyloid-beta metabolic process
0.38	GO:0007416	synapse assembly
0.36	GO:0043312	neutrophil degranulation
0.34	GO:0006415	translational termination

0.66	GO:0017171	serine hydrolase activity
0.61	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.51	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.54	GO:0031965	nuclear membrane
0.49	GO:0005829	cytosol
0.38	GO:0048786	presynaptic active zone
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen

sp|P13804|ETFA_HUMAN
Electron transfer flavoprotein subunit alpha, mitochondrial
Search

ETFA

0.46	Mitochondrial electron transfer flavoprotein subunit alpha

0.60	GO:0022900	electron transport chain
0.55	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.40	GO:0048567	ectodermal digestive tract morphogenesis
0.39	GO:0008258	head involution
0.39	GO:0007443	Malpighian tubule morphogenesis
0.39	GO:0007424	open tracheal system development
0.35	GO:0031998	regulation of fatty acid beta-oxidation
0.35	GO:0070584	mitochondrion morphogenesis
0.34	GO:0009887	animal organ morphogenesis
0.33	GO:0045333	cellular respiration

0.65	GO:0050660	flavin adenine dinucleotide binding
0.61	GO:0009055	electron transfer activity
0.34	GO:0005515	protein binding

0.45	GO:0005739	mitochondrion
0.37	GO:0045251	electron transfer flavoprotein complex
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part

sp|P13805|TNNT1_HUMAN
Troponin T, slow skeletal muscle
Search

TNNT1

0.95	Nemaline myopathy mutant slow skeletal muscle troponin T high molecular weight variant

0.81	GO:0006937	regulation of muscle contraction
0.53	GO:0006941	striated muscle contraction
0.50	GO:0014883	transition between fast and slow fiber
0.49	GO:0050881	musculoskeletal movement
0.46	GO:0097534	lymphoid lineage cell migration
0.46	GO:0010749	regulation of nitric oxide mediated signal transduction
0.46	GO:0051241	negative regulation of multicellular organismal process
0.46	GO:0048845	venous blood vessel morphogenesis
0.45	GO:0060218	hematopoietic stem cell differentiation
0.45	GO:0021591	ventricular system development

0.49	GO:0005523	tropomyosin binding
0.41	GO:0019901	protein kinase binding
0.40	GO:0031014	troponin T binding
0.40	GO:0019208	phosphatase regulator activity

0.84	GO:0005861	troponin complex
0.34	GO:0005829	cytosol

sp|P13807|GYS1_HUMAN
Glycogen [starch] synthase, muscle
Search

GYS1

0.69	Glycogen [starch] synthase, muscle

0.76	GO:0005978	glycogen biosynthetic process
0.50	GO:0007507	heart development
0.36	GO:0009749	response to glucose
0.35	GO:0090664	response to high population density
0.34	GO:0032868	response to insulin

0.80	GO:0004373	glycogen (starch) synthase activity
0.50	GO:0019901	protein kinase binding
0.40	GO:0061547	glycogen synthase activity, transferring glucose-1-phosphate
0.38	GO:0005536	glucose binding
0.34	GO:0009011	starch synthase activity

0.52	GO:0016234	inclusion body
0.38	GO:0005737	cytoplasm
0.34	GO:0099512	supramolecular fiber
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.32	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.80

EC:2.4.1.11

GO:0004373

sp|P13861|KAP2_HUMAN
cAMP-dependent protein kinase type II-alpha regulatory subunit
Search

PRKAR2A

0.96	cAMP-dependent protein kinase type II-alpha regulatory subunit

0.74	GO:0045859	regulation of protein kinase activity
0.57	GO:0033673	negative regulation of kinase activity
0.54	GO:0001933	negative regulation of protein phosphorylation
0.50	GO:0016310	phosphorylation
0.46	GO:0007612	learning
0.42	GO:0006631	fatty acid metabolic process
0.39	GO:0097338	response to clozapine
0.37	GO:1904146	positive regulation of meiotic cell cycle process involved in oocyte maturation
0.36	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0003091	renal water homeostasis

0.84	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.61	GO:0034236	protein kinase A catalytic subunit binding
0.61	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.56	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0016301	kinase activity
0.51	GO:0019904	protein domain specific binding
0.36	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0005476	carnitine:acyl carnitine antiporter activity
0.34	GO:0015226	carnitine transmembrane transporter activity

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.56	GO:0044441	ciliary part
0.55	GO:0005813	centrosome
0.54	GO:0031588	nucleotide-activated protein kinase complex
0.54	GO:0044853	plasma membrane raft
0.53	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.47	GO:0043198	dendritic shaft
0.47	GO:0043197	dendritic spine
0.37	GO:0070062	extracellular exosome
0.37	GO:0048471	perinuclear region of cytoplasm

sp|P13866|SC5A1_HUMAN
Sodium/glucose cotransporter 1
Search

SLC5A1

0.86	Low-affinity Na-dependent glucose cotransporter (Predicted)

0.58	GO:0015758	glucose transport
0.57	GO:1905950	monosaccharide transmembrane transport
0.49	GO:0006814	sodium ion transport
0.47	GO:0106001	intestinal hexose absorption
0.37	GO:0098655	cation transmembrane transport
0.37	GO:0001656	metanephros development
0.34	GO:0015992	proton transport
0.34	GO:0098660	inorganic ion transmembrane transport

0.63	GO:0005412	glucose:sodium symporter activity
0.39	GO:0005402	cation:sugar symporter activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.45	GO:0005887	integral component of plasma membrane
0.38	GO:0005903	brush border
0.37	GO:0016324	apical plasma membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0031253	cell projection membrane
0.36	GO:0005911	cell-cell junction

sp|P13928|ANXA8_HUMAN
Annexin A8
Search

0.65

Annexin

0.48	GO:0042060	wound healing
0.45	GO:0007599	hemostasis
0.44	GO:0010256	endomembrane system organization
0.43	GO:0050817	coagulation
0.42	GO:0050819	negative regulation of coagulation
0.40	GO:1900138	negative regulation of phospholipase A2 activity
0.40	GO:0009992	cellular water homeostasis
0.40	GO:0061024	membrane organization
0.39	GO:1900004	negative regulation of serine-type endopeptidase activity
0.39	GO:0035176	social behavior

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.41	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.41	GO:0032403	protein complex binding
0.41	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.40	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.40	GO:0048306	calcium-dependent protein binding
0.38	GO:0003779	actin binding
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0005102	receptor binding

0.41	GO:0031982	vesicle
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0012505	endomembrane system
0.39	GO:0005829	cytosol
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043230	extracellular organelle
0.37	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.36	GO:0005634	nucleus

sp|P13929|ENOB_HUMAN
Beta-enolase
Search

ENO3

0.83	Beta-enolase 3 transcript variant 1

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0046496	nicotinamide nucleotide metabolic process
0.38	GO:0043403	skeletal muscle tissue regeneration
0.38	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.38	GO:0010756	positive regulation of plasminogen activation
0.38	GO:2001171	positive regulation of ATP biosynthetic process
0.38	GO:1900038	negative regulation of cellular response to hypoxia
0.38	GO:0006006	glucose metabolic process

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0045296	cadherin binding
0.36	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0051020	GTPase binding
0.34	GO:0005212	structural constituent of eye lens

0.77	GO:0000015	phosphopyruvate hydratase complex
0.41	GO:0005886	plasma membrane
0.40	GO:0001917	photoreceptor inner segment
0.40	GO:0043204	perikaryon
0.39	GO:0043209	myelin sheath
0.37	GO:0044448	cell cortex part
0.36	GO:0009986	cell surface
0.36	GO:0070062	extracellular exosome
0.34	GO:0099023	tethering complex
0.33	GO:0043234	protein complex

0.78

EC:4.2.1.11

GO:0004634

sp|P13942|COBA2_HUMAN
Collagen alpha-2(XI) chain
Search

COL11A2

0.84	Collagen type XI alpha 2 chain

0.56	GO:0030199	collagen fibril organization
0.55	GO:0061448	connective tissue development
0.52	GO:0009887	animal organ morphogenesis
0.52	GO:0001501	skeletal system development
0.52	GO:0001894	tissue homeostasis
0.51	GO:0007605	sensory perception of sound
0.47	GO:0030154	cell differentiation
0.42	GO:0045112	integrin biosynthetic process
0.42	GO:0048729	tissue morphogenesis
0.41	GO:1903225	negative regulation of endodermal cell differentiation

0.79	GO:0005201	extracellular matrix structural constituent
0.41	GO:0043394	proteoglycan binding
0.41	GO:0008201	heparin binding
0.41	GO:0048407	platelet-derived growth factor binding
0.34	GO:0030674	protein binding, bridging
0.34	GO:0046872	metal ion binding
0.33	GO:0004871	signal transducer activity

0.72	GO:0005581	collagen trimer
0.43	GO:0098643	banded collagen fibril
0.39	GO:0005604	basement membrane
0.37	GO:0005615	extracellular space
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0005840	ribosome
0.33	GO:0098797	plasma membrane protein complex

sp|P13945|ADRB3_HUMAN
Beta-3 adrenergic receptor
Search

ADRB3

0.96	Beta-3 adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.83	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.69	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.65	GO:0001659	temperature homeostasis
0.65	GO:0002024	diet induced thermogenesis
0.64	GO:0040015	negative regulation of multicellular organism growth
0.62	GO:0007190	activation of adenylate cyclase activity
0.62	GO:0050873	brown fat cell differentiation
0.60	GO:1902533	positive regulation of intracellular signal transduction
0.60	GO:0010562	positive regulation of phosphorus metabolic process

0.86	GO:0004939	beta-adrenergic receptor activity
0.68	GO:0051380	norepinephrine binding
0.64	GO:0031690	adrenergic receptor binding
0.57	GO:0051379	epinephrine binding
0.54	GO:0042803	protein homodimerization activity
0.48	GO:0005057	signal transducer activity, downstream of receptor
0.48	GO:0030165	PDZ domain binding
0.48	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.44	GO:0046982	protein heterodimerization activity
0.37	GO:0008179	adenylate cyclase binding

0.56	GO:0043235	receptor complex
0.55	GO:0005886	plasma membrane
0.49	GO:0005769	early endosome
0.38	GO:0005634	nucleus
0.36	GO:0045177	apical part of cell
0.34	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

0.35

EC:2.6.1

GO:0008483

sp|P13984|T2FB_HUMAN
General transcription factor IIF subunit 2
Search

GTF2F2

0.92	General transcription factor IIF subunit 2

0.78	GO:0006367	transcription initiation from RNA polymerase II promoter
0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.47	GO:0031334	positive regulation of protein complex assembly
0.45	GO:0051254	positive regulation of RNA metabolic process
0.45	GO:0010557	positive regulation of macromolecule biosynthetic process
0.45	GO:0031328	positive regulation of cellular biosynthetic process
0.38	GO:0006413	translational initiation
0.35	GO:0042795	snRNA transcription by RNA polymerase II

0.61	GO:0004386	helicase activity
0.51	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0003677	DNA binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.38	GO:0003743	translation initiation factor activity
0.33	GO:0005515	protein binding

0.83	GO:0005674	transcription factor TFIIF complex
0.56	GO:0097550	transcriptional preinitiation complex
0.48	GO:0015630	microtubule cytoskeleton
0.35	GO:0005675	holo TFIIH complex

sp|P13985|HRES1_HUMAN
Putative HTLV-1-related endogenous sequence
Search

sp|P13987|CD59_HUMAN
CD59 glycoprotein
Search

CD59

0.88	Surface glycoprotein CD59 homolog

0.87	GO:0001971	negative regulation of activation of membrane attack complex
0.50	GO:0001775	cell activation
0.46	GO:0007166	cell surface receptor signaling pathway
0.43	GO:0002446	neutrophil mediated immunity
0.43	GO:0043299	leukocyte degranulation
0.42	GO:0048208	COPII vesicle coating
0.42	GO:0006955	immune response
0.41	GO:0007596	blood coagulation
0.36	GO:0006952	defense response

0.53

GO:0001848

complement binding

0.65	GO:0031225	anchored component of membrane
0.58	GO:0031233	intrinsic component of external side of plasma membrane
0.44	GO:0005576	extracellular region
0.44	GO:0035579	specific granule membrane
0.44	GO:0070821	tertiary granule membrane
0.42	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.41	GO:0005925	focal adhesion
0.41	GO:0012507	ER to Golgi transport vesicle membrane
0.40	GO:0000139	Golgi membrane
0.39	GO:0005789	endoplasmic reticulum membrane

sp|P13994|CC130_HUMAN
Coiled-coil domain-containing protein 130
Search

CCDC130

0.68	Coiled-coil domain-containing protein 94

0.74	GO:0009615	response to virus
0.36	GO:0043413	macromolecule glycosylation
0.36	GO:0009101	glycoprotein biosynthetic process
0.35	GO:0032259	methylation
0.34	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process
0.33	GO:0055114	oxidation-reduction process

0.38	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.38	GO:0005515	protein binding
0.35	GO:0051287	NAD binding
0.35	GO:0008168	methyltransferase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0003676	nucleic acid binding

0.36	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:2.4.1.135

GO:0015018

sp|P13995|MTDC_HUMAN
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
Search

MTHFD2

0.92	Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0006730	one-carbon metabolic process
0.46	GO:0046653	tetrahydrofolate metabolic process
0.38	GO:0046655	folic acid metabolic process
0.35	GO:0009086	methionine biosynthetic process
0.35	GO:0000105	histidine biosynthetic process
0.34	GO:0006164	purine nucleotide biosynthetic process

0.79	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.58	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity
0.50	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity
0.48	GO:0042301	phosphate ion binding
0.43	GO:0000287	magnesium ion binding

0.45	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.38	GO:0005615	extracellular space
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:1.5.1.5	GO:0004488
0.79	KEGG:R01220	GO:0004488

sp|P14060|3BHS1_HUMAN
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
Search

0.50	3 beta-hydroxysteroid dehydrogenase isomerase VI

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0008209	androgen metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.39	GO:0008212	mineralocorticoid metabolic process
0.38	GO:0008207	C21-steroid hormone metabolic process
0.38	GO:0008211	glucocorticoid metabolic process
0.38	GO:0014070	response to organic cyclic compound
0.37	GO:0010288	response to lead ion
0.37	GO:0033327	Leydig cell differentiation

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.54	GO:0004769	steroid delta-isomerase activity
0.53	GO:0102294	cholesterol dehydrogenase activity
0.38	GO:0010181	FMN binding
0.36	GO:0005496	steroid binding
0.36	GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity
0.35	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.35	GO:0051287	NAD binding
0.35	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.33	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.45	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.44	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.40	GO:0097425	smooth endoplasmic reticulum part
0.37	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.83

EC:1.1.1.145

GO:0003854

sp|P14061|DHB1_HUMAN
Estradiol 17-beta-dehydrogenase 1
Search

HSD17B1

0.89	Photoreceptor associated retinol dehydrogenase type 1

0.83	GO:0006703	estrogen biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0008209	androgen metabolic process
0.42	GO:0061370	testosterone biosynthetic process
0.41	GO:0060348	bone development
0.40	GO:0071248	cellular response to metal ion
0.36	GO:0042572	retinol metabolic process
0.35	GO:0015937	coenzyme A biosynthetic process
0.35	GO:0007601	visual perception
0.33	GO:0016310	phosphorylation

0.82	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.47	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.42	GO:1903924	estradiol binding
0.39	GO:0070401	NADP+ binding
0.36	GO:0004745	retinol dehydrogenase activity
0.36	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.36	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.35	GO:0004140	dephospho-CoA kinase activity
0.35	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.34	GO:0031132	serine 3-dehydrogenase activity

0.49	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.1.1.62	GO:0004303
0.47	KEGG:R01836	GO:0047035

sp|P14091|CATE_HUMAN
Cathepsin E
Search

CTSE

0.94	Cathepsin E-A

0.74	GO:0016540	protein autoprocessing
0.59	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.45	GO:0030163	protein catabolic process
0.43	GO:0007586	digestion
0.42	GO:0006914	autophagy
0.33	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.50	GO:0042803	protein homodimerization activity

0.53	GO:0005768	endosome
0.40	GO:0005576	extracellular region
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|P14136|GFAP_HUMAN
Glial fibrillary acidic protein
Search

GFAP

0.97	Glial fibrillary acidic protein transcript variant alpha

0.58	GO:0010625	positive regulation of Schwann cell proliferation
0.57	GO:1904714	regulation of chaperone-mediated autophagy
0.56	GO:0045109	intermediate filament organization
0.56	GO:0060020	Bergmann glial cell differentiation
0.55	GO:0014002	astrocyte development
0.55	GO:0051580	regulation of neurotransmitter uptake
0.55	GO:0031102	neuron projection regeneration
0.54	GO:0060291	long-term synaptic potentiation
0.53	GO:0010977	negative regulation of neuron projection development
0.51	GO:0030198	extracellular matrix organization

0.62	GO:0005198	structural molecule activity
0.49	GO:0042802	identical protein binding
0.38	GO:0005178	integrin binding
0.37	GO:0019900	kinase binding
0.35	GO:1990254	keratin filament binding
0.34	GO:0008092	cytoskeletal protein binding
0.34	GO:0097110	scaffold protein binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0003725	double-stranded RNA binding

0.79	GO:0005882	intermediate filament
0.57	GO:0097450	astrocyte end-foot
0.52	GO:0043209	myelin sheath
0.51	GO:0044297	cell body
0.42	GO:0097433	dense body
0.40	GO:0098574	cytoplasmic side of lysosomal membrane
0.37	GO:0014704	intercalated disc
0.37	GO:0042383	sarcolemma
0.37	GO:0030018	Z disc
0.36	GO:0097512	cardiac myofibril

sp|P14138|EDN3_HUMAN
Endothelin-3
Search

EDN3

0.88	Endothelin-3

0.85	GO:0019229	regulation of vasoconstriction
0.54	GO:0014826	vein smooth muscle contraction
0.54	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.53	GO:0010460	positive regulation of heart rate
0.52	GO:0008284	positive regulation of cell proliferation
0.52	GO:0030334	regulation of cell migration
0.52	GO:0030072	peptide hormone secretion
0.51	GO:0051050	positive regulation of transport
0.51	GO:0048016	inositol phosphate-mediated signaling
0.51	GO:0045840	positive regulation of mitotic nuclear division

0.54	GO:0031708	endothelin B receptor binding
0.49	GO:0005179	hormone activity
0.42	GO:0031707	endothelin A receptor binding
0.39	GO:0005125	cytokine activity
0.34	GO:0004459	L-lactate dehydrogenase activity
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.36	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

EC:1.1.1.27

GO:0004459

sp|P14151|LYAM1_HUMAN
L-selectin
Search

SELL

0.90	L-selectin

0.72	GO:0007155	cell adhesion
0.68	GO:0050900	leukocyte migration
0.51	GO:0033198	response to ATP
0.45	GO:0007202	activation of phospholipase C activity
0.45	GO:0002092	positive regulation of receptor internalization
0.44	GO:0070555	response to interleukin-1
0.41	GO:0030029	actin filament-based process
0.40	GO:0033623	regulation of integrin activation
0.39	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.39	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.63	GO:0030246	carbohydrate binding
0.52	GO:0005509	calcium ion binding
0.51	GO:0002020	protease binding
0.49	GO:0050839	cell adhesion molecule binding
0.48	GO:0033691	sialic acid binding
0.46	GO:0043274	phospholipase binding
0.40	GO:0004888	transmembrane signaling receptor activity
0.38	GO:0008201	heparin binding
0.38	GO:0001530	lipopolysaccharide binding
0.37	GO:0048306	calcium-dependent protein binding

0.51	GO:0009897	external side of plasma membrane
0.48	GO:0005887	integral component of plasma membrane
0.44	GO:0005901	caveola
0.43	GO:0005905	clathrin-coated pit
0.43	GO:0005615	extracellular space
0.43	GO:0030863	cortical cytoskeleton
0.43	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0031092	platelet alpha granule membrane

sp|P14174|MIF_HUMAN
Macrophage migration inhibitory factor
Search

MIF

0.85	Macrophage migration inhibitory factor

0.79	GO:0010760	negative regulation of macrophage chemotaxis
0.78	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.78	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.77	GO:0010739	positive regulation of protein kinase A signaling
0.76	GO:0090344	negative regulation of cell aging
0.76	GO:0070207	protein homotrimerization
0.76	GO:0048146	positive regulation of fibroblast proliferation
0.76	GO:0071157	negative regulation of cell cycle arrest
0.76	GO:0046457	prostanoid biosynthetic process
0.75	GO:0030890	positive regulation of B cell proliferation

0.85	GO:0050178	phenylpyruvate tautomerase activity
0.85	GO:0004167	dopachrome isomerase activity
0.76	GO:0042056	chemoattractant activity
0.74	GO:0005125	cytokine activity
0.69	GO:0005126	cytokine receptor binding
0.66	GO:0002020	protease binding
0.64	GO:0042802	identical protein binding
0.49	GO:0042289	MHC class II protein binding
0.37	GO:0032403	protein complex binding
0.33	GO:0003676	nucleic acid binding

0.68	GO:0005615	extracellular space
0.66	GO:0009986	cell surface
0.65	GO:0043209	myelin sheath
0.61	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.41	GO:1903561	extracellular vesicle
0.40	GO:1904813	ficolin-1-rich granule lumen
0.40	GO:0034774	secretory granule lumen

0.85	EC:5.3.2.1	GO:0050178
0.85	KEGG:R03673	GO:0004167

sp|P14207|FOLR2_HUMAN
Folate receptor beta
Search

0.72	Folate receptor gamma

0.85	GO:0015884	folic acid transport
0.61	GO:0071231	cellular response to folic acid
0.53	GO:0061713	anterior neural tube closure
0.52	GO:0003147	neural crest cell migration involved in heart formation
0.52	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis
0.51	GO:0061626	pharyngeal arch artery morphogenesis
0.50	GO:0031103	axon regeneration
0.49	GO:0001947	heart looping
0.48	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.48	GO:0060828	regulation of canonical Wnt signaling pathway

0.85	GO:0008517	folic acid transmembrane transporter activity
0.81	GO:0005542	folic acid binding
0.61	GO:0061714	folic acid receptor activity
0.60	GO:0051870	methotrexate binding
0.33	GO:0008270	zinc ion binding

0.58	GO:0031362	anchored component of external side of plasma membrane
0.48	GO:0016324	apical plasma membrane
0.48	GO:0016323	basolateral plasma membrane
0.41	GO:0031526	brush border membrane
0.41	GO:0005634	nucleus
0.39	GO:0031982	vesicle
0.39	GO:0005576	extracellular region
0.37	GO:0012505	endomembrane system
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0019898	extrinsic component of membrane

sp|P14209|CD99_HUMAN
CD99 antigen
Search

CD99

0.97	CD99 molecule (Xg blood group)

0.36	GO:0007155	cell adhesion
0.36	GO:0050776	regulation of immune response

0.35	GO:0005515	protein binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.37	GO:0005925	focal adhesion
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0005737	cytoplasm

0.33

EC:2.4

GO:0016757

sp|P14210|HGF_HUMAN
Hepatocyte growth factor
Search

HGF

0.85	Hepatocyte growth factor

0.68	GO:0010469	regulation of receptor activity
0.67	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.63	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
0.63	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death
0.62	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.62	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.62	GO:0051450	myoblast proliferation
0.62	GO:1902947	regulation of tau-protein kinase activity
0.61	GO:0006508	proteolysis
0.60	GO:0050918	positive chemotaxis

0.71	GO:0048018	receptor ligand activity
0.69	GO:0004252	serine-type endopeptidase activity
0.53	GO:0042802	identical protein binding
0.41	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.38	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.38	GO:0004713	protein tyrosine kinase activity
0.38	GO:0046982	protein heterodimerization activity

0.47	GO:0005615	extracellular space
0.41	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

0.69	EC:3.4.21	GO:0004252
0.41	KEGG:R04545	GO:0046934

sp|P14222|PERF_HUMAN
Perforin-1
Search

PRF1

0.93	Perforin 1 (Pore forming protein)

0.75	GO:0019835	cytolysis
0.71	GO:0002418	immune response to tumor cell
0.71	GO:0002357	defense response to tumor cell
0.69	GO:0001771	immunological synapse formation
0.63	GO:0051712	positive regulation of killing of cells of other organism
0.60	GO:0051260	protein homooligomerization
0.60	GO:0051607	defense response to virus
0.46	GO:0055085	transmembrane transport
0.39	GO:0006915	apoptotic process
0.39	GO:0006968	cellular defense response

0.68	GO:0005509	calcium ion binding
0.59	GO:0022829	wide pore channel activity
0.58	GO:0042802	identical protein binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0008289	lipid binding

0.69	GO:0044194	cytolytic granule
0.57	GO:0031410	cytoplasmic vesicle
0.54	GO:0005829	cytosol
0.48	GO:0005579	membrane attack complex
0.39	GO:0012505	endomembrane system
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0005576	extracellular region
0.36	GO:0044446	intracellular organelle part

sp|P14314|GLU2B_HUMAN
Glucosidase 2 subunit beta
Search

PRKCSH

0.85	LOW QUALITY PROTEIN: glucosidase 2 subunit beta

0.84	GO:0006491	N-glycan processing
0.61	GO:0001889	liver development
0.60	GO:0072001	renal system development
0.57	GO:0010977	negative regulation of neuron projection development
0.55	GO:0001701	in utero embryonic development
0.40	GO:0016310	phosphorylation
0.40	GO:0051291	protein heterooligomerization
0.36	GO:0043687	post-translational protein modification
0.34	GO:0006457	protein folding
0.34	GO:0035556	intracellular signal transduction

0.67	GO:0005509	calcium ion binding
0.45	GO:0003723	RNA binding
0.41	GO:0016301	kinase activity
0.40	GO:0005080	protein kinase C binding
0.40	GO:0044325	ion channel binding
0.40	GO:0051219	phosphoprotein binding
0.32	GO:0016787	hydrolase activity

0.51	GO:0005783	endoplasmic reticulum
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0016787

sp|P14316|IRF2_HUMAN
Interferon regulatory factor 2
Search

IRF2

0.89	Interferon regulatory factor

0.80	GO:0008283	cell proliferation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051607	defense response to virus
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:0060337	type I interferon signaling pathway
0.36	GO:0060333	interferon-gamma-mediated signaling pathway
0.35	GO:0007596	blood coagulation

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:1990837	sequence-specific double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.56	GO:0005925	focal adhesion
0.49	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P14317|HCLS1_HUMAN
Hematopoietic lineage cell-specific protein
Search

HCLS1

0.86	Hematopoietic cell-specific Lyn substrate 1

0.83	GO:0030041	actin filament polymerization
0.66	GO:0030854	positive regulation of granulocyte differentiation
0.64	GO:0045651	positive regulation of macrophage differentiation
0.63	GO:2000107	negative regulation of leukocyte apoptotic process
0.63	GO:0042993	positive regulation of transcription factor import into nucleus
0.63	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.63	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.62	GO:0051897	positive regulation of protein kinase B signaling
0.62	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.62	GO:0030218	erythrocyte differentiation

0.72	GO:0003779	actin binding
0.61	GO:0001085	RNA polymerase II transcription factor binding
0.58	GO:0017124	SH3 domain binding
0.58	GO:0019901	protein kinase binding
0.55	GO:0032403	protein complex binding
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.56	GO:0005667	transcription factor complex
0.53	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.45	GO:0005886	plasma membrane
0.36	GO:0005739	mitochondrion
0.34	GO:0005794	Golgi apparatus

0.32

GO:0016491

sp|P14324|FPPS_HUMAN
Farnesyl pyrophosphate synthase
Search

FDPS

0.50	Farnesyl pyrophosphate synthetase

0.69	GO:0008299	isoprenoid biosynthetic process
0.49	GO:0045338	farnesyl diphosphate metabolic process
0.45	GO:0033383	geranyl diphosphate metabolic process
0.43	GO:0006695	cholesterol biosynthetic process
0.43	GO:0008654	phospholipid biosynthetic process
0.40	GO:0045540	regulation of cholesterol biosynthetic process
0.37	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development
0.37	GO:0090205	positive regulation of cholesterol metabolic process
0.36	GO:0033574	response to testosterone
0.36	GO:0070723	response to cholesterol

0.49	GO:0016740	transferase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0003723	RNA binding

0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.35	GO:0005777	peroxisome
0.30	GO:0016021	integral component of membrane

0.49

GO:0016740

sp|P14373|TRI27_HUMAN
Zinc finger protein RFP
Search

TRIM27

0.86	Zinc finger protein RFP

0.63	GO:1900041	negative regulation of interleukin-2 secretion
0.63	GO:0072643	interferon-gamma secretion
0.61	GO:0032897	negative regulation of viral transcription
0.61	GO:0090281	negative regulation of calcium ion import
0.60	GO:1902187	negative regulation of viral release from host cell
0.60	GO:0032720	negative regulation of tumor necrosis factor production
0.60	GO:0070534	protein K63-linked ubiquitination
0.59	GO:0051127	positive regulation of actin nucleation
0.57	GO:0070206	protein trimerization
0.57	GO:0051091	positive regulation of DNA binding transcription factor activity

0.61	GO:0008270	zinc ion binding
0.53	GO:0042802	identical protein binding
0.53	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0016874	ligase activity
0.36	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0003677	DNA binding
0.33	GO:0003779	actin binding

0.58	GO:0001650	fibrillar center
0.57	GO:0030904	retromer complex
0.56	GO:0031965	nuclear membrane
0.54	GO:0005768	endosome
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0005875	microtubule associated complex
0.33	GO:0005739	mitochondrion

0.39	EC:6	GO:0016874
0.53	KEGG:R03876	GO:0004842

sp|P14384|CBPM_HUMAN
Carboxypeptidase M
Search

CPM

0.95	Carboxypeptidase M

0.61	GO:0006508	proteolysis
0.44	GO:0051604	protein maturation
0.40	GO:0006518	peptide metabolic process
0.36	GO:0006501	C-terminal protein lipidation
0.34	GO:0009653	anatomical structure morphogenesis
0.31	GO:0043604	amide biosynthetic process

0.77	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.46	GO:0004185	serine-type carboxypeptidase activity
0.32	GO:0003735	structural constituent of ribosome

0.46	GO:0009986	cell surface
0.45	GO:0005615	extracellular space
0.38	GO:0031225	anchored component of membrane
0.37	GO:1903561	extracellular vesicle
0.34	GO:0005886	plasma membrane
0.31	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.77

GO:0004181

sp|P14406|CX7A2_HUMAN
Cytochrome c oxidase subunit 7A2, mitochondrial
Search

COX7A2

0.97	Cytochrome c oxidase polypeptide VIIa-liver/heart, mitochondrial

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.79	GO:0005746	mitochondrial respiratory chain
0.39	GO:0070062	extracellular exosome
0.34	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9

GO:0016675

sp|P14410|SUIS_HUMAN
Sucrase-isomaltase, intestinal
Search

0.53	Maltase-glucoamylase, intestinal

0.60	GO:0005975	carbohydrate metabolic process
0.30	GO:0007586	digestion

0.70	GO:0030246	carbohydrate binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.30	GO:0005794	Golgi apparatus
0.30	GO:0005903	brush border
0.30	GO:0070062	extracellular exosome
0.30	GO:0045177	apical part of cell
0.30	GO:0044459	plasma membrane part
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004553

sp|P14415|AT1B2_HUMAN
Sodium/potassium-transporting ATPase subunit beta-2
Search

ATP1B2

0.79	Sodium/potassium-transporting ATPase subunit beta

0.71	GO:0006814	sodium ion transport
0.70	GO:0006813	potassium ion transport
0.63	GO:1903288	positive regulation of potassium ion import
0.63	GO:1903278	positive regulation of sodium ion export across plasma membrane
0.62	GO:0006883	cellular sodium ion homeostasis
0.61	GO:0086009	membrane repolarization
0.61	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.59	GO:0030007	cellular potassium ion homeostasis
0.59	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.58	GO:0140115	export across plasma membrane

0.60	GO:0051117	ATPase binding
0.59	GO:0005391	sodium:potassium-exchanging ATPase activity
0.57	GO:0001671	ATPase activator activity

0.83	GO:0005890	sodium:potassium-exchanging ATPase complex
0.56	GO:0016324	apical plasma membrane
0.40	GO:0005737	cytoplasm

0.59

GO:0005391

sp|P14416|DRD2_HUMAN
D(2) dopamine receptor
Search

DRD2

0.95	Dopamine receptor 2 protein transcript variant 1

0.85	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway
0.64	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.64	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway
0.63	GO:0048148	behavioral response to cocaine
0.63	GO:0014059	regulation of dopamine secretion
0.62	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.62	GO:0048149	behavioral response to ethanol
0.62	GO:1900166	regulation of glial cell-derived neurotrophic factor secretion
0.62	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.62	GO:0035815	positive regulation of renal sodium excretion

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.63	GO:0035240	dopamine binding
0.52	GO:0042802	identical protein binding
0.49	GO:0004935	adrenergic receptor activity
0.41	GO:0035255	ionotropic glutamate receptor binding
0.38	GO:0046982	protein heterodimerization activity
0.36	GO:0015459	potassium channel regulator activity

0.66	GO:0005887	integral component of plasma membrane
0.58	GO:0060170	ciliary membrane
0.56	GO:0097730	non-motile cilium
0.56	GO:0030425	dendrite
0.55	GO:0030424	axon
0.50	GO:0030672	synaptic vesicle membrane
0.40	GO:0043204	perikaryon
0.40	GO:0016328	lateral plasma membrane
0.40	GO:0044309	neuron spine
0.40	GO:0043679	axon terminus

sp|P14543|NID1_HUMAN
Nidogen-1
Search

NID1

0.92

Nidogen-1

0.80	GO:0007160	cell-matrix adhesion
0.58	GO:0032836	glomerular basement membrane development
0.55	GO:0010811	positive regulation of cell-substrate adhesion
0.37	GO:0022617	extracellular matrix disassembly
0.36	GO:0071711	basement membrane organization
0.32	GO:0006979	response to oxidative stress
0.32	GO:0098869	cellular oxidant detoxification
0.31	GO:0055114	oxidation-reduction process

0.69	GO:0005509	calcium ion binding
0.59	GO:0043237	laminin-1 binding
0.58	GO:0043394	proteoglycan binding
0.56	GO:0005518	collagen binding
0.32	GO:0004096	catalase activity
0.31	GO:0020037	heme binding

0.57	GO:0005605	basal lamina
0.50	GO:0005615	extracellular space
0.42	GO:0071944	cell periphery
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.32

EC:1.11.1.6

GO:0004096

sp|P14550|AK1A1_HUMAN
Alcohol dehydrogenase [NADP(+)]
Search

AKR1A1

0.39	Alcohol dehydrogenase

0.59	GO:0042840	D-glucuronate catabolic process
0.57	GO:0019853	L-ascorbic acid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0046185	aldehyde catabolic process
0.36	GO:0019640	glucuronate catabolic process to xylulose 5-phosphate
0.36	GO:1901685	glutathione derivative metabolic process
0.35	GO:0006335	DNA replication-dependent nucleosome assembly
0.35	GO:0006336	DNA replication-independent nucleosome assembly
0.34	GO:0006006	glucose metabolic process
0.33	GO:0044272	sulfur compound biosynthetic process

0.60	GO:0047939	L-glucuronate reductase activity
0.58	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.34	GO:0042393	histone binding
0.33	GO:0009055	electron transfer activity

0.53	GO:0016324	apical plasma membrane
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0000790	nuclear chromatin
0.33	GO:0005654	nucleoplasm
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.60	EC:1.1.1.19	GO:0047939
0.60	KEGG:R01481	GO:0047939

sp|P14555|PA2GA_HUMAN
Phospholipase A2, membrane associated
Search

0.65	Acidic phospholipase A2 jerdoxin

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.47	GO:0009405	pathogenesis
0.46	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.42	GO:0046486	glycerolipid metabolic process
0.37	GO:0042742	defense response to bacterium
0.37	GO:0034374	low-density lipoprotein particle remodeling
0.36	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.36	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

0.82	GO:0004623	phospholipase A2 activity
0.74	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.74	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.70	GO:0005509	calcium ion binding
0.49	GO:0090729	toxin activity
0.44	GO:0005543	phospholipid binding
0.35	GO:0043395	heparan sulfate proteoglycan binding
0.35	GO:0008201	heparin binding
0.32	GO:0008061	chitin binding

0.66	GO:0005576	extracellular region
0.42	GO:0005783	endoplasmic reticulum
0.39	GO:0072556	other organism presynaptic membrane
0.37	GO:0030141	secretory granule
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0035792	other organism postsynaptic membrane
0.35	GO:0005886	plasma membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:3.1.1.4

GO:0004623

sp|P14598|NCF1_HUMAN
Neutrophil cytosol factor 1
Search

NCF1

0.97	Neutrophil cytosolic factor 1

0.57	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity
0.56	GO:1900745	positive regulation of p38MAPK cascade
0.56	GO:0042554	superoxide anion generation
0.55	GO:0071276	cellular response to cadmium ion
0.55	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.54	GO:0046330	positive regulation of JNK cascade
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0071800	podosome assembly
0.50	GO:1901700	response to oxygen-containing compound
0.50	GO:0006612	protein targeting to membrane

0.85	GO:0016175	superoxide-generating NADPH oxidase activity
0.76	GO:0035091	phosphatidylinositol binding
0.52	GO:0017124	SH3 domain binding
0.51	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.34	GO:0008942	nitrite reductase [NAD(P)H] activity
0.34	GO:0003677	DNA binding
0.33	GO:0009055	electron transfer activity

0.56	GO:0043020	NADPH oxidase complex
0.50	GO:0019898	extrinsic component of membrane
0.50	GO:0002102	podosome
0.49	GO:0005737	cytoplasm
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.36	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0097708	intracellular vesicle

0.85	EC:1.6.3	GO:0016175
0.34	KEGG:R00787 KEGG:R00789	GO:0008942

sp|P14616|INSRR_HUMAN
Insulin receptor-related protein
Search

0.62	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.76	GO:0046777	protein autophosphorylation
0.73	GO:0071469	cellular response to alkaline pH
0.57	GO:0030238	male sex determination
0.53	GO:0031532	actin cytoskeleton reorganization
0.43	GO:0051389	inactivation of MAPKK activity
0.43	GO:0097242	amyloid-beta clearance
0.43	GO:0045740	positive regulation of DNA replication
0.42	GO:1904646	cellular response to amyloid-beta

0.83	GO:0043560	insulin receptor substrate binding
0.82	GO:0043548	phosphatidylinositol 3-kinase binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.46	GO:0005520	insulin-like growth factor binding
0.45	GO:0043559	insulin binding
0.42	GO:0005158	insulin receptor binding

0.57	GO:0005887	integral component of plasma membrane
0.56	GO:0043235	receptor complex
0.43	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.37	GO:0106003	amyloid-beta complex
0.36	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0005901	caveola
0.35	GO:1902911	protein kinase complex
0.34	GO:0012505	endomembrane system
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0031967	organelle envelope

0.80

GO:0004714

sp|P14618|KPYM_HUMAN
Pyruvate kinase PKM
Search

PKM

0.47	Pyruvate kinase PKM

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.47	GO:0012501	programmed cell death
0.47	GO:0032868	response to insulin
0.46	GO:0071375	cellular response to peptide hormone stimulus
0.39	GO:0014870	response to muscle inactivity
0.38	GO:0043403	skeletal muscle tissue regeneration
0.38	GO:0031100	animal organ regeneration

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.49	GO:0045296	cadherin binding
0.39	GO:0070324	thyroid hormone binding
0.37	GO:0023026	MHC class II protein complex binding
0.37	GO:0043531	ADP binding
0.36	GO:0042802	identical protein binding
0.36	GO:0005524	ATP binding

0.49	GO:0043209	myelin sheath
0.47	GO:0005929	cilium
0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.40	GO:1902912	pyruvate kinase complex
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.78

EC:2.7.1.40

GO:0004743

sp|P14621|ACYP2_HUMAN
Acylphosphatase-2
Search

ACYP2

0.50	Acylphosphatase

0.45	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0046944	protein carbamoylation
0.34	GO:0051693	actin filament capping
0.33	GO:1901642	nucleoside transmembrane transport
0.33	GO:0007010	cytoskeleton organization
0.32	GO:0006261	DNA-dependent DNA replication
0.32	GO:0071897	DNA biosynthetic process
0.32	GO:0006281	DNA repair

0.80	GO:0003998	acylphosphatase activity
0.45	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0042802	identical protein binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0003725	double-stranded RNA binding
0.34	GO:0016743	carboxyl- or carbamoyltransferase activity
0.34	GO:0005543	phospholipid binding

0.42	GO:0005739	mitochondrion
0.34	GO:0008091	spectrin
0.33	GO:0005887	integral component of plasma membrane

0.80

EC:3.6.1.7

GO:0003998

sp|P14625|ENPL_HUMAN
Endoplasmin
Search

HSP90B1

0.84	Heat shock protein HSP 90-alpha

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.58	GO:0031247	actin rod assembly
0.57	GO:0071318	cellular response to ATP
0.55	GO:1903513	endoplasmic reticulum to cytosol transport
0.55	GO:0032527	protein exit from endoplasmic reticulum
0.53	GO:0036293	response to decreased oxygen levels
0.52	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.51	GO:0043666	regulation of phosphoprotein phosphatase activity
0.51	GO:0043066	negative regulation of apoptotic process

0.71	GO:0051082	unfolded protein binding
0.55	GO:0050750	low-density lipoprotein particle receptor binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0019903	protein phosphatase binding
0.43	GO:0003723	RNA binding
0.34	GO:0005509	calcium ion binding

0.55	GO:0005788	endoplasmic reticulum lumen
0.53	GO:0030496	midbody
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0034663	endoplasmic reticulum chaperone complex
0.48	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005829	cytosol
0.44	GO:0042470	melanosome
0.39	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

sp|P14635|CCNB1_HUMAN
G2/mitotic-specific cyclin-B1
Search

CCNB1

0.77	Cyclin B1 transcript variant 1

0.56	GO:2000775	histone H3-S10 phosphorylation involved in chromosome condensation
0.55	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.55	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.53	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore
0.52	GO:0048146	positive regulation of fibroblast proliferation
0.52	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.52	GO:0007080	mitotic metaphase plate congression
0.52	GO:0001701	in utero embryonic development
0.51	GO:0007052	mitotic spindle organization
0.50	GO:0045931	positive regulation of mitotic cell cycle

0.54	GO:0005113	patched binding
0.52	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.49	GO:0044389	ubiquitin-like protein ligase binding
0.49	GO:0019901	protein kinase binding
0.42	GO:0016301	kinase activity
0.39	GO:0045296	cadherin binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0060089	molecular transducer activity
0.33	GO:0008324	cation transmembrane transporter activity

0.61	GO:0005634	nucleus
0.55	GO:0097125	cyclin B1-CDK1 complex
0.51	GO:0005813	centrosome
0.50	GO:0000940	condensed chromosome outer kinetochore
0.49	GO:0000922	spindle pole
0.48	GO:0005759	mitochondrial matrix
0.47	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.37

GO:0016773

sp|P14649|MYL6B_HUMAN
Myosin light chain 6B
Search

MYL6B

0.94	Myosin, light chain 6, alkali, smooth muscle and non-muscle

0.42	GO:0030049	muscle filament sliding
0.39	GO:0007519	skeletal muscle tissue development
0.34	GO:0030239	myofibril assembly

0.70	GO:0005509	calcium ion binding
0.49	GO:0008307	structural constituent of muscle
0.40	GO:0030898	actin-dependent ATPase activity
0.38	GO:0003774	motor activity
0.35	GO:0005515	protein binding
0.33	GO:0043531	ADP binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0000287	magnesium ion binding

0.50	GO:0016461	unconventional myosin complex
0.46	GO:0005903	brush border
0.39	GO:0070062	extracellular exosome
0.37	GO:0005859	muscle myosin complex
0.37	GO:0031012	extracellular matrix
0.37	GO:0005829	cytosol
0.35	GO:0097513	myosin II filament
0.34	GO:0042641	actomyosin
0.30	GO:0016020	membrane

sp|P14651|HXB3_HUMAN
Homeobox protein Hox-B3
Search

0.91	Homeobox protein Hox-B3

0.64	GO:0007275	multicellular organism development
0.56	GO:0061448	connective tissue development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0051960	regulation of nervous system development
0.54	GO:0060284	regulation of cell development
0.54	GO:0060324	face development
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.51	GO:0030154	cell differentiation

0.62	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.46	GO:0016235	aggresome
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part

sp|P14652|HXB2_HUMAN
Homeobox protein Hox-B2
Search

HOXA2

0.96	Homeobox protein Hox-B2

0.69	GO:0007275	multicellular organism development
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048857	neural nucleus development
0.55	GO:0048532	anatomical structure arrangement
0.54	GO:0002011	morphogenesis of an epithelial sheet
0.52	GO:0060322	head development
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.46	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P14653|HXB1_HUMAN
Homeobox protein Hox-B1
Search

HOXB1

0.95	Homeobox protein Hox-B1

0.65	GO:0021570	rhombomere 4 development
0.64	GO:0021754	facial nucleus development
0.64	GO:0021571	rhombomere 5 development
0.62	GO:0021612	facial nerve structural organization
0.60	GO:0048704	embryonic skeletal system morphogenesis
0.57	GO:0009952	anterior/posterior pattern specification
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0048646	anatomical structure formation involved in morphogenesis
0.54	GO:0006366	transcription by RNA polymerase II
0.42	GO:0021598	abducens nerve morphogenesis

0.63	GO:0043565	sequence-specific DNA binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0019904	protein domain specific binding
0.52	GO:0003690	double-stranded DNA binding
0.38	GO:0042802	identical protein binding
0.32	GO:0016301	kinase activity

0.60	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|P14672|GTR4_HUMAN
Solute carrier family 2, facilitated glucose transporter member 4
Search

SLC2A4

0.87	Solute carrier family 2, facilitated glucose transporter member 4

0.77	GO:1904659	glucose transmembrane transport
0.72	GO:0032868	response to insulin
0.68	GO:0071375	cellular response to peptide hormone stimulus
0.57	GO:0010021	amylopectin biosynthetic process
0.55	GO:0050873	brown fat cell differentiation
0.55	GO:0046323	glucose import
0.53	GO:0071356	cellular response to tumor necrosis factor
0.53	GO:0071470	cellular response to osmotic stress
0.52	GO:0042593	glucose homeostasis
0.49	GO:0070837	dehydroascorbic acid transport

0.78	GO:0005355	glucose transmembrane transporter activity
0.49	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.48	GO:0043621	protein self-association
0.44	GO:0042802	identical protein binding
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.36	GO:0019900	kinase binding
0.36	GO:0009679	hexose:proton symporter activity

0.57	GO:0032593	insulin-responsive compartment
0.56	GO:0045121	membrane raft
0.54	GO:0042383	sarcolemma
0.52	GO:0070062	extracellular exosome
0.52	GO:0009897	external side of plasma membrane
0.52	GO:0030140	trans-Golgi network transport vesicle
0.52	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005829	cytosol
0.50	GO:0012506	vesicle membrane
0.50	GO:0005887	integral component of plasma membrane

sp|P14678|RSMB_HUMAN
Small nuclear ribonucleoprotein-associated proteins B and B'
Search

SNRPB

0.85	Small nuclear ribonucleoprotein-associated proteins B and B'

0.51	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0022618	ribonucleoprotein complex assembly
0.43	GO:0008213	protein alkylation
0.41	GO:0043414	macromolecule methylation
0.37	GO:0009725	response to hormone
0.35	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0007420	brain development
0.34	GO:0051170	nuclear import

0.57	GO:0003723	RNA binding
0.35	GO:1990447	U2 snRNP binding
0.35	GO:1990446	U1 snRNP binding
0.34	GO:0005515	protein binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.59	GO:0005634	nucleus
0.57	GO:0019013	viral nucleocapsid
0.52	GO:0120114	Sm-like protein family complex
0.49	GO:0034709	methylosome
0.46	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005829	cytosol
0.40	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome

sp|P14679|TYRO_HUMAN
Tyrosinase
Search

TYR

0.61	Truncated tyrosinase

0.59	GO:0042438	melanin biosynthetic process
0.57	GO:0048538	thymus development
0.55	GO:0043473	pigmentation
0.53	GO:0008283	cell proliferation
0.52	GO:0055114	oxidation-reduction process
0.42	GO:0033280	response to vitamin D
0.41	GO:0051591	response to cAMP
0.40	GO:0009411	response to UV
0.36	GO:0006570	tyrosine metabolic process
0.35	GO:0042416	dopamine biosynthetic process

0.71	GO:0004503	monophenol monooxygenase activity
0.53	GO:0046872	metal ion binding
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.35	GO:0004097	catechol oxidase activity

0.58	GO:0042470	melanosome
0.53	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0090741	pigment granule membrane
0.43	GO:0045009	chitosome
0.43	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0098805	whole membrane
0.38	GO:0005829	cytosol
0.35	GO:0005798	Golgi-associated vesicle
0.30	GO:0016021	integral component of membrane

0.71

EC:1.14.18.1

GO:0004503

sp|P14735|IDE_HUMAN
Insulin-degrading enzyme
Search

IDE

0.85	Insulin-degrading enzyme

0.60	GO:0006508	proteolysis
0.59	GO:1901143	insulin catabolic process
0.58	GO:0010815	bradykinin catabolic process
0.57	GO:0050435	amyloid-beta metabolic process
0.56	GO:0032461	positive regulation of protein oligomerization
0.56	GO:0010992	ubiquitin recycling
0.54	GO:0008340	determination of adult lifespan
0.51	GO:0051260	protein homooligomerization
0.48	GO:0044257	cellular protein catabolic process
0.47	GO:1990798	pancreas regeneration

0.69	GO:0004222	metalloendopeptidase activity
0.58	GO:0043559	insulin binding
0.58	GO:0140036	ubiquitin-dependent protein binding
0.54	GO:0046872	metal ion binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0005102	receptor binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0031626	beta-endorphin binding

0.50	GO:0005777	peroxisome
0.50	GO:0009986	cell surface
0.49	GO:0005615	extracellular space
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.38	GO:0031907	microbody lumen
0.36	GO:1905369	endopeptidase complex
0.34	GO:0005886	plasma membrane
0.34	GO:0043234	protein complex

0.69

GO:0004222

sp|P14770|GPIX_HUMAN
Platelet glycoprotein IX
Search

GP9

0.97	Glycoprotein Ib platelet beta subunit

0.44	GO:0032501	multicellular organismal process
0.43	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.43	GO:0000904	cell morphogenesis involved in differentiation
0.42	GO:0120036	plasma membrane bounded cell projection organization
0.42	GO:0051414	response to cortisol
0.42	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.41	GO:1902742	apoptotic process involved in development
0.41	GO:0007599	hemostasis
0.41	GO:0050919	negative chemotaxis
0.41	GO:0035385	Roundabout signaling pathway

0.42	GO:0005509	calcium ion binding
0.42	GO:0048495	Roundabout binding
0.35	GO:0004180	carboxypeptidase activity
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0004860	protein kinase inhibitor activity
0.34	GO:0004963	follicle-stimulating hormone receptor activity
0.34	GO:0004601	peroxidase activity
0.33	GO:0020037	heme binding

0.43	GO:0005576	extracellular region
0.36	GO:0005887	integral component of plasma membrane
0.32	GO:0005739	mitochondrion

0.34	EC:1.11.1.7	GO:0004601
0.34	KEGG:R03532	GO:0004601

sp|P14778|IL1R1_HUMAN
Interleukin-1 receptor type 1
Search

IL1R1

0.97	Interleukin 1 beta receptor type 1 short transmembrane form

0.83	GO:0070498	interleukin-1-mediated signaling pathway
0.62	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway
0.61	GO:2000391	positive regulation of neutrophil extravasation
0.58	GO:0050727	regulation of inflammatory response
0.45	GO:0045582	positive regulation of T cell differentiation
0.45	GO:0032755	positive regulation of interleukin-6 production
0.36	GO:1990834	response to odorant
0.36	GO:2001224	positive regulation of neuron migration
0.36	GO:0071731	response to nitric oxide
0.36	GO:0030728	ovulation

0.85	GO:0004909	interleukin-1, Type I, activating receptor activity
0.60	GO:0005161	platelet-derived growth factor receptor binding
0.60	GO:0019966	interleukin-1 binding
0.57	GO:0002020	protease binding
0.36	GO:0035255	ionotropic glutamate receptor binding
0.34	GO:0002113	interleukin-33 binding
0.34	GO:0002114	interleukin-33 receptor activity

0.55	GO:0009897	external side of plasma membrane
0.37	GO:0005576	extracellular region
0.35	GO:0014069	postsynaptic density
0.35	GO:0030424	axon
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus
0.33	GO:0043234	protein complex

sp|P14780|MMP9_HUMAN
Matrix metalloproteinase-9
Search

MMP2

0.63	Matrix metalloproteinase

0.73	GO:0030574	collagen catabolic process
0.69	GO:0001503	ossification
0.68	GO:0050900	leukocyte migration
0.61	GO:0006508	proteolysis
0.52	GO:0009653	anatomical structure morphogenesis
0.52	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.51	GO:0007275	multicellular organism development
0.51	GO:0030154	cell differentiation
0.50	GO:0007492	endoderm development
0.50	GO:0007565	female pregnancy

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.44	GO:0042802	identical protein binding
0.32	GO:0004252	serine-type endopeptidase activity
0.30	GO:0032403	protein complex binding

0.74	GO:0031012	extracellular matrix
0.46	GO:0005615	extracellular space
0.40	GO:0030017	sarcomere
0.36	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.30	GO:0031410	cytoplasmic vesicle
0.30	GO:0070013	intracellular organelle lumen
0.30	GO:0043230	extracellular organelle
0.30	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|P14784|IL2RB_HUMAN
Interleukin-2 receptor subunit beta
Search

IL2RB

0.95	Interleukin-2 receptor subunit beta

0.79	GO:0019221	cytokine-mediated signaling pathway
0.69	GO:0071352	cellular response to interleukin-2
0.60	GO:0043066	negative regulation of apoptotic process
0.42	GO:0071350	cellular response to interleukin-15
0.39	GO:0000165	MAPK cascade
0.38	GO:0030101	natural killer cell activation
0.37	GO:0006461	protein complex assembly
0.37	GO:0065009	regulation of molecular function
0.36	GO:0016032	viral process

0.80	GO:0004896	cytokine receptor activity
0.68	GO:0019976	interleukin-2 binding
0.39	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.62	GO:0009897	external side of plasma membrane
0.38	GO:0005768	endosome
0.37	GO:0005829	cytosol
0.37	GO:0005887	integral component of plasma membrane

sp|P14854|CX6B1_HUMAN
Cytochrome c oxidase subunit 6B1
Search

COX6B1

0.74	Cytochrome c oxidase subunit

0.39	GO:0021762	substantia nigra development
0.35	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen
0.34	GO:0034968	histone lysine methylation
0.34	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0006355	regulation of transcription, DNA-templated

0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0015002	heme-copper terminal oxidase activity
0.34	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0009055	electron transfer activity
0.33	GO:0008270	zinc ion binding

0.61	GO:0005739	mitochondrion
0.43	GO:0031967	organelle envelope
0.42	GO:0031090	organelle membrane
0.38	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.34	GO:0045277	respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016676

sp|P14859|PO2F1_HUMAN
POU domain, class 2, transcription factor 1
Search

POU2F1

0.72	POU domain, class 2, transcription factor 1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0060019	radial glial cell differentiation
0.37	GO:0030910	olfactory placode formation
0.37	GO:0060235	lens induction in camera-type eye
0.36	GO:0007219	Notch signaling pathway

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001047	core promoter binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.37	GO:0001223	transcription coactivator binding
0.35	GO:0003682	chromatin binding
0.34	GO:0005102	receptor binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part

sp|P14866|HNRPL_HUMAN
Heterogeneous nuclear ribonucleoprotein L
Search

HNRNPL

0.86	Heterogeneous nuclear ribonucleoprotein L

0.67	GO:0006397	mRNA processing
0.52	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.35	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.35	GO:1902416	positive regulation of mRNA binding
0.35	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.35	GO:0034198	cellular response to amino acid starvation
0.34	GO:0007623	circadian rhythm
0.34	GO:1901652	response to peptide
0.34	GO:0045727	positive regulation of translation

0.58	GO:0003723	RNA binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.62	GO:0019013	viral nucleocapsid
0.59	GO:0005634	nucleus
0.55	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P14867|GBRA1_HUMAN
Gamma-aminobutyric acid receptor subunit alpha-1
Search

GABRA1

0.97	Gamma-aminobutyric acid receptor subunit alpha-1

0.83	GO:0007214	gamma-aminobutyric acid signaling pathway
0.74	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0060078	regulation of postsynaptic membrane potential
0.40	GO:0071420	cellular response to histamine
0.40	GO:0051932	synaptic transmission, GABAergic
0.35	GO:0006836	neurotransmitter transport
0.34	GO:0001505	regulation of neurotransmitter levels

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.55	GO:0099095	ligand-gated anion channel activity
0.53	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.52	GO:0005254	chloride channel activity
0.51	GO:0022835	transmitter-gated channel activity
0.39	GO:0008503	benzodiazepine receptor activity
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.58	GO:1902711	GABA-A receptor complex
0.56	GO:0005886	plasma membrane
0.46	GO:0098794	postsynapse
0.45	GO:0060077	inhibitory synapse
0.43	GO:0043025	neuronal cell body
0.42	GO:0030425	dendrite
0.42	GO:0030424	axon
0.42	GO:0034707	chloride channel complex
0.40	GO:0030054	cell junction
0.40	GO:0030659	cytoplasmic vesicle membrane

sp|P14868|SYDC_HUMAN
Aspartate--tRNA ligase, cytoplasmic
Search

DARS

0.64	Aspartyl-tRNA synthetase

0.79	GO:0006422	aspartyl-tRNA aminoacylation
0.34	GO:0006461	protein complex assembly

0.79	GO:0004815	aspartate-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003676	nucleic acid binding
0.35	GO:0004046	aminoacylase activity
0.34	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.57	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.49	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.79

EC:6.1.1.12

GO:0004815

sp|P14902|I23O1_HUMAN
Indoleamine 2,3-dioxygenase 1
Search

IDO1

0.81	Indoleamine 2,3-dioxygenase

0.77	GO:0019441	tryptophan catabolic process to kynurenine
0.64	GO:0002534	cytokine production involved in inflammatory response
0.63	GO:0002678	positive regulation of chronic inflammatory response
0.62	GO:0002666	positive regulation of T cell tolerance induction
0.62	GO:0034276	kynurenic acid biosynthetic process
0.62	GO:0036269	swimming behavior
0.62	GO:0070234	positive regulation of T cell apoptotic process
0.62	GO:0002830	positive regulation of type 2 immune response
0.61	GO:0032693	negative regulation of interleukin-10 production
0.61	GO:0070233	negative regulation of T cell apoptotic process

0.66	GO:0051213	dioxygenase activity
0.62	GO:0020037	heme binding
0.53	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
0.53	GO:0046872	metal ion binding
0.35	GO:0019825	oxygen binding
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0016597	amino acid binding
0.34	GO:0009055	electron transfer activity
0.34	GO:0005515	protein binding

0.62	GO:0030485	smooth muscle contractile fiber
0.59	GO:0032421	stereocilium bundle
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.53

EC:1.13

GO:0016701

sp|P14920|OXDA_HUMAN
D-amino-acid oxidase
Search

DAO

0.62	Peroxisomal sarcosine oxidase

0.76	GO:0046416	D-amino acid metabolic process
0.60	GO:0042416	dopamine biosynthetic process
0.55	GO:0009080	pyruvate family amino acid catabolic process
0.54	GO:0006562	proline catabolic process
0.54	GO:0046144	D-alanine family amino acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.53	GO:0009071	serine family amino acid catabolic process
0.50	GO:0042737	drug catabolic process
0.36	GO:0006551	leucine metabolic process
0.34	GO:0007625	grooming behavior

0.83	GO:0003884	D-amino-acid oxidase activity
0.73	GO:0071949	FAD binding
0.51	GO:0005102	receptor binding
0.49	GO:0046983	protein dimerization activity
0.33	GO:0015922	aspartate oxidase activity

0.55	GO:0005777	peroxisome
0.54	GO:0031903	microbody membrane
0.53	GO:0005741	mitochondrial outer membrane
0.49	GO:0005829	cytosol
0.36	GO:0031907	microbody lumen
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.4.3.3

GO:0003884

sp|P14921|ETS1_HUMAN
Protein C-ets-1
Search

ETS1

0.71	ETS proto-oncogene 1, transcription factor

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030578	PML body organization
0.55	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell
0.54	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.54	GO:0045648	positive regulation of erythrocyte differentiation
0.53	GO:0010595	positive regulation of endothelial cell migration
0.52	GO:0043535	regulation of blood vessel endothelial cell migration
0.51	GO:0045765	regulation of angiogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0042802	identical protein binding
0.47	GO:0003690	double-stranded DNA binding
0.40	GO:0035035	histone acetyltransferase binding
0.34	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.33	GO:0042025	host cell nucleus
0.33	GO:0005737	cytoplasm

sp|P14923|PLAK_HUMAN
Junction plakoglobin
Search

JUP

0.97	Junction plakoglobin b

0.85	GO:0034333	adherens junction assembly
0.80	GO:0002159	desmosome assembly
0.66	GO:0007155	cell adhesion
0.61	GO:0007165	signal transduction
0.60	GO:0071681	cellular response to indole-3-methanol
0.57	GO:0086069	bundle of His cell to Purkinje myocyte communication
0.57	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.56	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.56	GO:0086091	regulation of heart rate by cardiac conduction
0.56	GO:0001954	positive regulation of cell-matrix adhesion

0.81	GO:0045294	alpha-catenin binding
0.74	GO:0045296	cadherin binding
0.64	GO:0004871	signal transducer activity
0.58	GO:0019903	protein phosphatase binding
0.56	GO:0005198	structural molecule activity
0.54	GO:0003713	transcription coactivator activity
0.42	GO:0019901	protein kinase binding
0.40	GO:0070411	I-SMAD binding
0.40	GO:0030331	estrogen receptor binding
0.40	GO:0097718	disordered domain specific binding

0.81	GO:0016342	catenin complex
0.76	GO:0005913	cell-cell adherens junction
0.60	GO:0071664	catenin-TCF7L2 complex
0.59	GO:0030057	desmosome
0.58	GO:0014704	intercalated disc
0.56	GO:0030018	Z disc
0.52	GO:0005882	intermediate filament
0.50	GO:0032993	protein-DNA complex
0.48	GO:0005829	cytosol
0.43	GO:0016328	lateral plasma membrane

sp|P14927|QCR7_HUMAN
Cytochrome b-c1 complex subunit 7
Search

UQCRB

0.75	Cytochrome b-c1 complex subunit 7

0.72	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.46	GO:0017062	respiratory chain complex III assembly
0.46	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.45	GO:0033108	mitochondrial respiratory chain complex assembly
0.43	GO:0001525	angiogenesis
0.40	GO:0009060	aerobic respiration
0.40	GO:0007406	negative regulation of neuroblast proliferation
0.35	GO:0051291	protein heterooligomerization
0.34	GO:0008340	determination of adult lifespan
0.33	GO:0000302	response to reactive oxygen species

0.43	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.40	GO:0009055	electron transfer activity
0.34	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.81

GO:0005750

mitochondrial respiratory chain complex III

0.43

GO:0016681

sp|P15018|LIF_HUMAN
Leukemia inhibitory factor
Search

LIF

0.96	Leukemia inhibitory factor

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.61	GO:1901676	positive regulation of histone H3-K27 acetylation
0.60	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
0.60	GO:0060708	spongiotrophoblast differentiation
0.60	GO:0048861	leukemia inhibitory factor signaling pathway
0.60	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation
0.59	GO:0060426	lung vasculature development
0.59	GO:0060463	lung lobe morphogenesis
0.59	GO:0007260	tyrosine phosphorylation of STAT protein

0.87	GO:0005146	leukemia inhibitory factor receptor binding
0.81	GO:0005125	cytokine activity
0.54	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.47	GO:0005829	cytosol

sp|P15036|ETS2_HUMAN
Protein C-ets-2
Search

ETS2

0.65	ETS proto-oncogene 2, transcription factor

0.60	GO:0001712	ectodermal cell fate commitment
0.59	GO:0090009	primitive streak formation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007498	mesoderm development
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process
0.50	GO:0051253	negative regulation of RNA metabolic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0019904	protein domain specific binding
0.51	GO:0003690	double-stranded DNA binding
0.41	GO:0035259	glucocorticoid receptor binding
0.34	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005886	plasma membrane
0.34	GO:0005667	transcription factor complex
0.33	GO:0042025	host cell nucleus

sp|P15056|BRAF_HUMAN
Serine/threonine-protein kinase B-raf
Search

BRAF

0.79	V-raf murine sarcoma viral oncogene homolog B1

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.44	GO:0018212	peptidyl-tyrosine modification

0.78	GO:0005057	signal transducer activity, downstream of receptor
0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.44	GO:0004713	protein tyrosine kinase activity

0.45

GO:0005622

intracellular

0.70

GO:0004674

sp|P15085|CBPA1_HUMAN
Carboxypeptidase A1
Search

CPA1

0.88	Carboxypeptidase A

0.60	GO:0006508	proteolysis
0.34	GO:0044257	cellular protein catabolic process

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.51	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.76

GO:0004181

sp|P15086|CBPB1_HUMAN
Carboxypeptidase B
Search

CPB1

0.79	Pancreatic carboxypeptidase B

0.60	GO:0006508	proteolysis
0.44	GO:0002002	regulation of angiotensin levels in blood
0.35	GO:0071466	cellular response to xenobiotic stimulus

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding

0.47	GO:0044421	extracellular region part
0.39	GO:0046658	anchored component of plasma membrane
0.34	GO:0030133	transport vesicle
0.33	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.76

GO:0004181

sp|P15088|CBPA3_HUMAN
Mast cell carboxypeptidase A
Search

CPA3

0.84	Mast cell carboxypeptidase A

0.71	GO:0002002	regulation of angiotensin levels in blood
0.61	GO:0006508	proteolysis
0.42	GO:0042445	hormone metabolic process
0.41	GO:0051604	protein maturation
0.38	GO:0006518	peptide metabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding

0.61	GO:0031012	extracellular matrix
0.51	GO:0030133	transport vesicle
0.49	GO:0005615	extracellular space
0.44	GO:0030141	secretory granule
0.30	GO:0016021	integral component of membrane

0.78

GO:0004181

sp|P15090|FABP4_HUMAN
Fatty acid-binding protein, adipocyte
Search

FABP4

0.81	Adipocyte fatty acid-binding protein 4

0.76	GO:0050727	regulation of inflammatory response
0.64	GO:0050872	white fat cell differentiation
0.64	GO:0071285	cellular response to lithium ion
0.63	GO:0042632	cholesterol homeostasis
0.61	GO:0050873	brown fat cell differentiation
0.60	GO:0001816	cytokine production
0.59	GO:0071356	cellular response to tumor necrosis factor
0.58	GO:0032103	positive regulation of response to external stimulus
0.58	GO:0006469	negative regulation of protein kinase activity
0.58	GO:0031349	positive regulation of defense response

0.82	GO:0005504	fatty acid binding
0.39	GO:0008092	cytoskeletal protein binding

0.45	GO:0043209	myelin sheath
0.41	GO:0005615	extracellular space
0.39	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.38	GO:0005811	lipid droplet
0.38	GO:1903561	extracellular vesicle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|P15104|GLNA_HUMAN
Glutamine synthetase
Search

GLUL

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.49	GO:0008283	cell proliferation
0.48	GO:0009749	response to glucose
0.47	GO:0031667	response to nutrient levels
0.44	GO:0031668	cellular response to extracellular stimulus
0.42	GO:0033554	cellular response to stress
0.39	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.39	GO:0019676	ammonia assimilation cycle
0.39	GO:0032024	positive regulation of insulin secretion
0.38	GO:0050679	positive regulation of epithelial cell proliferation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.43	GO:0004351	glutamate decarboxylase activity
0.40	GO:0016595	glutamate binding
0.39	GO:0045503	dynein light chain binding
0.37	GO:0030145	manganese ion binding
0.36	GO:0000287	magnesium ion binding

0.50	GO:0097386	glial cell projection
0.48	GO:0043209	myelin sheath
0.47	GO:0044297	cell body
0.45	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0036477	somatodendritic compartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|P15121|ALDR_HUMAN
Aldose reductase
Search

AKR1B1

0.39	Aldo-keto reductase

0.54	GO:0044598	doxorubicin metabolic process
0.54	GO:0044597	daunorubicin metabolic process
0.53	GO:0071475	cellular hyperosmotic salinity response
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0003091	renal water homeostasis
0.50	GO:0035809	regulation of urine volume
0.47	GO:0072001	renal system development
0.46	GO:0043066	negative regulation of apoptotic process
0.42	GO:0006061	sorbitol biosynthetic process
0.42	GO:0090420	naphthalene-containing compound metabolic process

0.55	GO:0043795	glyceraldehyde oxidoreductase activity
0.55	GO:0004032	alditol:NADP+ 1-oxidoreductase activity
0.35	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.35	GO:0047718	indanol dehydrogenase activity
0.35	GO:0001758	retinal dehydrogenase activity
0.34	GO:0045550	geranylgeranyl reductase activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0005515	protein binding

0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:0097454	Schwann cell microvillus
0.41	GO:0033010	paranodal junction
0.41	GO:0043220	Schmidt-Lanterman incisure
0.41	GO:0042629	mast cell granule
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle

0.55	EC:1.1.1.21	GO:0004032
0.55	KEGG:R02820	GO:0004032

sp|P15144|AMPN_HUMAN
Aminopeptidase N
Search

ANPEP

0.51	Aminopeptidase Ey

0.60	GO:0006508	proteolysis
0.48	GO:0008217	regulation of blood pressure
0.46	GO:0043171	peptide catabolic process
0.45	GO:0007267	cell-cell signaling
0.43	GO:0001525	angiogenesis
0.41	GO:0007165	signal transduction
0.41	GO:0030154	cell differentiation
0.38	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.38	GO:0044409	entry into host
0.37	GO:0019058	viral life cycle

0.70	GO:0004177	aminopeptidase activity
0.66	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.47	GO:0042277	peptide binding
0.42	GO:0104005	hijacked molecular function
0.34	GO:0004872	receptor activity

0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.54	GO:0070062	extracellular exosome
0.53	GO:0009897	external side of plasma membrane
0.42	GO:0005765	lysosomal membrane
0.36	GO:0012506	vesicle membrane
0.35	GO:0031983	vesicle lumen
0.35	GO:0030141	secretory granule
0.35	GO:0044433	cytoplasmic vesicle part
0.30	GO:0031224	intrinsic component of membrane

0.70

EC:3.4.11

GO:0004177

sp|P15151|PVR_HUMAN
Poliovirus receptor
Search

PVR

0.97	Poliovirus receptor

0.62	GO:0007286	spermatid development
0.59	GO:0060370	susceptibility to T cell mediated cytotoxicity
0.58	GO:0007155	cell adhesion
0.58	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity
0.58	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell
0.57	GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.53	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.53	GO:0044409	entry into host
0.52	GO:0030382	sperm mitochondrion organization
0.52	GO:0046814	coreceptor-mediated virion attachment to host cell

0.63	GO:0050839	cell adhesion molecule binding
0.60	GO:0042803	protein homodimerization activity
0.56	GO:0046982	protein heterodimerization activity
0.45	GO:0005102	receptor binding
0.43	GO:0004872	receptor activity
0.41	GO:0104005	hijacked molecular function
0.36	GO:0045503	dynein light chain binding
0.35	GO:0001784	phosphotyrosine residue binding
0.34	GO:0004871	signal transducer activity
0.33	GO:0005509	calcium ion binding

0.60	GO:0005911	cell-cell junction
0.53	GO:0005912	adherens junction
0.46	GO:0009986	cell surface
0.43	GO:0005887	integral component of plasma membrane
0.41	GO:0030055	cell-substrate junction
0.41	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus

sp|P15153|RAC2_HUMAN
Ras-related C3 botulinum toxin substrate 2
Search

RAC2

0.97	Rac family small GTPase 2

0.77	GO:0007264	small GTPase mediated signal transduction
0.61	GO:1902624	positive regulation of neutrophil migration
0.60	GO:0060263	regulation of respiratory burst
0.60	GO:0010592	positive regulation of lamellipodium assembly
0.59	GO:0071624	positive regulation of granulocyte chemotaxis
0.59	GO:0090022	regulation of neutrophil chemotaxis
0.58	GO:0071593	lymphocyte aggregation
0.58	GO:0060753	regulation of mast cell chemotaxis
0.57	GO:0043304	regulation of mast cell degranulation
0.56	GO:0010810	regulation of cell-substrate adhesion

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.52	GO:0019887	protein kinase regulator activity
0.43	GO:0031996	thioesterase binding
0.41	GO:0019901	protein kinase binding
0.37	GO:0051022	Rho GDP-dissociation inhibitor binding
0.36	GO:0004994	somatostatin receptor activity
0.35	GO:0030742	GTP-dependent protein binding
0.34	GO:0051117	ATPase binding
0.34	GO:0042826	histone deacetylase binding

0.56	GO:0005884	actin filament
0.56	GO:0030027	lamellipodium
0.51	GO:0005635	nuclear envelope
0.48	GO:0005829	cytosol
0.42	GO:0055038	recycling endosome membrane
0.42	GO:0032587	ruffle membrane
0.42	GO:0043197	dendritic spine
0.41	GO:0005802	trans-Golgi network
0.41	GO:0036464	cytoplasmic ribonucleoprotein granule
0.37	GO:0005925	focal adhesion

0.33

GO:0004674

sp|P15169|CBPN_HUMAN
Carboxypeptidase N catalytic chain
Search

CPN1

0.97	Carboxypeptidase N catalytic chain

0.61	GO:0006508	proteolysis
0.50	GO:1901142	insulin metabolic process
0.45	GO:0051604	protein maturation
0.45	GO:0042445	hormone metabolic process
0.41	GO:0006518	peptide metabolic process
0.39	GO:0051384	response to glucocorticoid
0.38	GO:0071391	cellular response to estrogen stimulus
0.37	GO:0001889	liver development
0.37	GO:0035023	regulation of Rho protein signal transduction
0.36	GO:0042737	drug catabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.46	GO:0004185	serine-type carboxypeptidase activity
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.47	GO:0043025	neuronal cell body
0.47	GO:0030141	secretory granule
0.46	GO:0005615	extracellular space
0.46	GO:0097060	synaptic membrane
0.44	GO:0005794	Golgi apparatus
0.34	GO:0005578	proteinaceous extracellular matrix
0.33	GO:1903561	extracellular vesicle
0.33	GO:0030658	transport vesicle membrane

0.78

GO:0004181

sp|P15170|ERF3A_HUMAN
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
Search

GSPT1

0.91	G1 to S phase transition 1

0.55	GO:0006415	translational termination
0.53	GO:0008213	protein alkylation
0.49	GO:0043414	macromolecule methylation
0.49	GO:0002181	cytoplasmic translation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.56	GO:0008079	translation termination factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0018444	translation release factor complex
0.45	GO:0005829	cytosol

sp|P15172|MYOD1_HUMAN
Myoblast determination protein 1
Search

MYOD1

0.91	Myogenic factor

0.79	GO:0007517	muscle organ development
0.62	GO:0043503	skeletal muscle fiber adaptation
0.62	GO:0007518	myoblast fate determination
0.61	GO:0014908	myotube differentiation involved in skeletal muscle regeneration
0.60	GO:2000818	negative regulation of myoblast proliferation
0.60	GO:1901741	positive regulation of myoblast fusion
0.60	GO:0043415	positive regulation of skeletal muscle tissue regeneration
0.59	GO:0014904	myotube cell development
0.58	GO:0071392	cellular response to estradiol stimulus
0.58	GO:0048747	muscle fiber development

0.67	GO:0046983	protein dimerization activity
0.57	GO:0035257	nuclear hormone receptor binding
0.56	GO:0031490	chromatin DNA binding
0.56	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0001047	core promoter binding
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0003713	transcription coactivator activity
0.45	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.36	GO:0005249	voltage-gated potassium channel activity

0.60	GO:0005634	nucleus
0.54	GO:0030016	myofibril
0.52	GO:0005667	transcription factor complex
0.50	GO:0000785	chromatin
0.49	GO:0005829	cytosol
0.49	GO:0070013	intracellular organelle lumen
0.36	GO:0008076	voltage-gated potassium channel complex

sp|P15173|MYOG_HUMAN
Myogenin
Search

MYOG

0.97	Myogenic factor MyoG

0.81	GO:0007517	muscle organ development
0.63	GO:0048743	positive regulation of skeletal muscle fiber development
0.63	GO:0014737	positive regulation of muscle atrophy
0.61	GO:1901739	regulation of myoblast fusion
0.61	GO:0014894	response to denervation involved in regulation of muscle adaptation
0.61	GO:0014891	striated muscle atrophy
0.61	GO:0045663	positive regulation of myoblast differentiation
0.60	GO:0014706	striated muscle tissue development
0.60	GO:0071285	cellular response to lithium ion
0.60	GO:0014842	regulation of skeletal muscle satellite cell proliferation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0070888	E-box binding
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0031490	chromatin DNA binding
0.56	GO:0001047	core promoter binding
0.55	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.32	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.39	GO:0032993	protein-DNA complex
0.35	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.32

EC:3.1.3.48

GO:0004725

sp|P15248|IL9_HUMAN
Interleukin-9
Search

IL9

0.97	Interleukin-9

0.78	GO:0045405	regulation of interleukin-5 biosynthetic process
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.74	GO:0032754	positive regulation of interleukin-5 production
0.70	GO:0042108	positive regulation of cytokine biosynthetic process
0.44	GO:0038113	interleukin-9-mediated signaling pathway
0.43	GO:0030307	positive regulation of cell growth
0.40	GO:0006954	inflammatory response
0.40	GO:0008284	positive regulation of cell proliferation

0.79	GO:0005126	cytokine receptor binding
0.78	GO:0008083	growth factor activity
0.45	GO:0005125	cytokine activity
0.43	GO:0070851	growth factor receptor binding

0.66

GO:0005576

extracellular region

sp|P15259|PGAM2_HUMAN
Phosphoglycerate mutase 2
Search

PGAM2

0.48	Phosphoglycerate mutase

0.69	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.66	GO:0019362	pyridine nucleotide metabolic process
0.56	GO:0043456	regulation of pentose-phosphate shunt
0.54	GO:0006941	striated muscle contraction
0.51	GO:0007219	Notch signaling pathway
0.47	GO:0019319	hexose biosynthetic process
0.47	GO:0006006	glucose metabolic process
0.42	GO:0045730	respiratory burst

0.85	GO:0004082	bisphosphoglycerate mutase activity
0.77	GO:0004619	phosphoglycerate mutase activity
0.40	GO:0019901	protein kinase binding
0.35	GO:0016787	hydrolase activity
0.34	GO:0048037	cofactor binding
0.33	GO:0034061	DNA polymerase activity
0.32	GO:0003677	DNA binding

0.46	GO:0005829	cytosol
0.45	GO:0043209	myelin sheath
0.38	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

0.85

EC:5.4.2.4

GO:0004082

sp|P15260|INGR1_HUMAN
Interferon gamma receptor 1
Search

IFNGR1

0.94	Interferon-gamma receptor alpha chain

0.50	GO:0019221	cytokine-mediated signaling pathway
0.42	GO:0009615	response to virus
0.41	GO:0006952	defense response
0.41	GO:0002376	immune system process
0.40	GO:0060330	regulation of response to interferon-gamma
0.38	GO:0001959	regulation of cytokine-mediated signaling pathway

0.84	GO:0019955	cytokine binding
0.51	GO:0004896	cytokine receptor activity

0.41	GO:0005886	plasma membrane
0.36	GO:0014069	postsynaptic density
0.36	GO:0030425	dendrite
0.35	GO:0031982	vesicle
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|P15289|ARSA_HUMAN
Arylsulfatase A
Search

ARSA

0.58	Arylsulfatase A

0.56	GO:0007339	binding of sperm to zona pellucida
0.42	GO:0051597	response to methylmercury
0.41	GO:0043627	response to estrogen
0.41	GO:0045471	response to ethanol
0.40	GO:0009268	response to pH
0.40	GO:0007584	response to nutrient
0.39	GO:0007417	central nervous system development
0.39	GO:0006914	autophagy
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0006687	glycosphingolipid metabolic process

0.74	GO:0008484	sulfuric ester hydrolase activity
0.39	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding

0.50	GO:0005615	extracellular space
0.42	GO:0031232	extrinsic component of external side of plasma membrane
0.42	GO:0005764	lysosome
0.41	GO:0030141	secretory granule
0.40	GO:0097223	sperm part
0.39	GO:0005768	endosome
0.39	GO:1903561	extracellular vesicle
0.36	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0005775	vacuolar lumen
0.36	GO:0005788	endoplasmic reticulum lumen

0.74

EC:3.1.6

GO:0008484

sp|P15291|B4GT1_HUMAN
Beta-1,4-galactosyltransferase 1
Search

B4GALT1

0.89	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1

0.60	GO:0005975	carbohydrate metabolic process
0.60	GO:0060058	positive regulation of apoptotic process involved in mammary gland involution
0.59	GO:0007341	penetration of zona pellucida
0.59	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing
0.59	GO:0045136	development of secondary sexual characteristics
0.58	GO:0060046	regulation of acrosome reaction
0.57	GO:0060055	angiogenesis involved in wound healing
0.57	GO:0007339	binding of sperm to zona pellucida
0.56	GO:0002526	acute inflammatory response
0.55	GO:0048754	branching morphogenesis of an epithelial tube

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.50	GO:0030145	manganese ion binding
0.49	GO:0008092	cytoskeletal protein binding
0.37	GO:0042803	protein homodimerization activity

0.58	GO:0000138	Golgi trans cisterna
0.57	GO:0030057	desmosome
0.57	GO:0031526	brush border membrane
0.55	GO:0016323	basolateral plasma membrane
0.54	GO:0009897	external side of plasma membrane
0.50	GO:0005615	extracellular space
0.39	GO:0032580	Golgi cisterna membrane
0.39	GO:0030175	filopodium
0.36	GO:0035577	azurophil granule membrane
0.35	GO:1903561	extracellular vesicle

0.65

EC:2.4

GO:0016757

sp|P15309|PPAP_HUMAN
Prostatic acid phosphatase
Search

ACPP

0.82	Prostatic acid phosphatase

0.66	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.64	GO:0051930	regulation of sensory perception of pain
0.63	GO:0046085	adenosine metabolic process
0.57	GO:0051289	protein homotetramerization
0.55	GO:0016311	dephosphorylation
0.54	GO:0006772	thiamine metabolic process
0.51	GO:0006144	purine nucleobase metabolic process
0.47	GO:0007040	lysosome organization
0.46	GO:0001501	skeletal system development
0.44	GO:0009117	nucleotide metabolic process

0.67	GO:0052642	lysophosphatidic acid phosphatase activity
0.65	GO:0042131	thiamine phosphate phosphatase activity
0.58	GO:0008253	5'-nucleotidase activity
0.52	GO:0042803	protein homodimerization activity
0.35	GO:0033265	choline binding

0.56	GO:0030175	filopodium
0.55	GO:0012506	vesicle membrane
0.55	GO:0005615	extracellular space
0.47	GO:0005764	lysosome
0.45	GO:0005886	plasma membrane
0.40	GO:0098852	lytic vacuole membrane
0.38	GO:1903561	extracellular vesicle
0.37	GO:0005775	vacuolar lumen
0.37	GO:0030141	secretory granule
0.35	GO:0005771	multivesicular body

0.58

EC:3.1.3.5

GO:0008253

sp|P15311|EZRI_HUMAN
Ezrin
Search

EZR

0.97	Epididymis secretory protein Li 105

0.56	GO:0022614	membrane to membrane docking
0.56	GO:1902965	regulation of protein localization to early endosome
0.56	GO:2000643	positive regulation of early endosome to late endosome transport
0.56	GO:1905668	positive regulation of protein localization to endosome
0.54	GO:0061028	establishment of endothelial barrier
0.54	GO:0007159	leukocyte cell-cell adhesion
0.54	GO:0035088	establishment or maintenance of apical/basal cell polarity
0.53	GO:1900041	negative regulation of interleukin-2 secretion
0.53	GO:1902896	terminal web assembly
0.53	GO:0001951	intestinal D-glucose absorption

0.73	GO:0003779	actin binding
0.52	GO:0050839	cell adhesion molecule binding
0.52	GO:0034236	protein kinase A catalytic subunit binding
0.51	GO:0044548	S100 protein binding
0.51	GO:0034237	protein kinase A regulatory subunit binding
0.51	GO:0097718	disordered domain specific binding
0.51	GO:0051117	ATPase binding
0.50	GO:0008022	protein C-terminus binding
0.47	GO:0032403	protein complex binding
0.46	GO:0008017	microtubule binding

0.69	GO:0005856	cytoskeleton
0.56	GO:0071437	invadopodium
0.54	GO:0001931	uropod
0.54	GO:0005902	microvillus
0.53	GO:0030175	filopodium
0.53	GO:0098592	cytoplasmic side of apical plasma membrane
0.52	GO:0005925	focal adhesion
0.51	GO:0043209	myelin sheath
0.51	GO:0001772	immunological synapse
0.51	GO:0048471	perinuclear region of cytoplasm

0.34

GO:0004714

sp|P15313|VATB1_HUMAN
V-type proton ATPase subunit B, kidney isoform
Search

0.86	Vacuolar-type H+ transporting ATPase B2 subunit

0.74	GO:0015991	ATP hydrolysis coupled proton transport
0.64	GO:0007588	excretion
0.63	GO:0045851	pH reduction
0.62	GO:0042472	inner ear morphogenesis
0.61	GO:0001503	ossification
0.61	GO:0007605	sensory perception of sound
0.60	GO:0046034	ATP metabolic process
0.60	GO:0055074	calcium ion homeostasis
0.39	GO:0097401	synaptic vesicle lumen acidification

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0032403	protein complex binding

0.78	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.71	GO:0005902	microvillus
0.62	GO:0016328	lateral plasma membrane
0.61	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.61	GO:0016323	basolateral plasma membrane
0.61	GO:0016324	apical plasma membrane
0.58	GO:0005829	cytosol
0.54	GO:0001726	ruffle
0.54	GO:0043209	myelin sheath
0.43	GO:0098850	extrinsic component of synaptic vesicle membrane

sp|P15328|FOLR1_HUMAN
Folate receptor alpha
Search

0.72	Folate receptor alpha

0.85	GO:0015884	folic acid transport
0.62	GO:0071231	cellular response to folic acid
0.55	GO:0061713	anterior neural tube closure
0.55	GO:0003147	neural crest cell migration involved in heart formation
0.54	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis
0.53	GO:0061626	pharyngeal arch artery morphogenesis
0.52	GO:0031103	axon regeneration
0.51	GO:0001947	heart looping
0.51	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.50	GO:0060828	regulation of canonical Wnt signaling pathway

0.85	GO:0008517	folic acid transmembrane transporter activity
0.82	GO:0005542	folic acid binding
0.62	GO:0061714	folic acid receptor activity
0.61	GO:0051870	methotrexate binding
0.33	GO:0008270	zinc ion binding

0.58	GO:0031362	anchored component of external side of plasma membrane
0.50	GO:0016324	apical plasma membrane
0.50	GO:0016323	basolateral plasma membrane
0.42	GO:0031526	brush border membrane
0.42	GO:0005634	nucleus
0.40	GO:0031982	vesicle
0.39	GO:0005576	extracellular region
0.37	GO:0012505	endomembrane system
0.36	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0098805	whole membrane

sp|P15336|ATF2_HUMAN
Cyclic AMP-dependent transcription factor ATF-2
Search

ATF2

0.93	Cyclic AMP-dependent transcription factor ATF-2

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0032915	positive regulation of transforming growth factor beta2 production
0.58	GO:0110024	positive regulation of cardiac muscle myoblast proliferation
0.56	GO:0060612	adipose tissue development
0.56	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process
0.56	GO:0003151	outflow tract morphogenesis
0.55	GO:0045444	fat cell differentiation
0.54	GO:0031573	intra-S DNA damage checkpoint
0.53	GO:0016525	negative regulation of angiogenesis
0.52	GO:0051091	positive regulation of DNA binding transcription factor activity

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0008140	cAMP response element binding protein binding
0.54	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0035497	cAMP response element binding
0.54	GO:0001102	RNA polymerase II activating transcription factor binding
0.52	GO:0004402	histone acetyltransferase activity
0.51	GO:0003682	chromatin binding
0.51	GO:0019901	protein kinase binding
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.54	GO:0035861	site of double-strand break
0.51	GO:0005741	mitochondrial outer membrane
0.46	GO:0070013	intracellular organelle lumen
0.33	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.52

EC:2.3.1.48

GO:0004402

sp|P15374|UCHL3_HUMAN
Ubiquitin carboxyl-terminal hydrolase isozyme L3
Search

UCHL3

0.57	Ubiquitin carboxyl-terminal hydrolase

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0016579	protein deubiquitination
0.42	GO:1904888	cranial skeletal system development
0.42	GO:0007219	Notch signaling pathway
0.37	GO:0042755	eating behavior
0.37	GO:0007628	adult walking behavior
0.37	GO:0045600	positive regulation of fat cell differentiation
0.37	GO:0032869	cellular response to insulin stimulus
0.37	GO:0060041	retina development in camera-type eye
0.35	GO:0043687	post-translational protein modification

0.78	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.49	GO:0043130	ubiquitin binding
0.35	GO:0019784	NEDD8-specific protease activity

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.35	GO:0043196	varicosity
0.30	GO:0016020	membrane

sp|P15382|KCNE1_HUMAN
Potassium voltage-gated channel subfamily E member 1
Search

KCNE1

0.96	Potassium channel, voltage-gated subfamily E regulatory beta subunit 1

0.73	GO:0071804	cellular potassium ion transport
0.63	GO:0086091	regulation of heart rate by cardiac conduction
0.63	GO:0002070	epithelial cell maturation
0.62	GO:0098662	inorganic cation transmembrane transport
0.61	GO:0060047	heart contraction
0.60	GO:1902260	negative regulation of delayed rectifier potassium channel activity
0.53	GO:0006487	protein N-linked glycosylation
0.53	GO:0006493	protein O-linked glycosylation
0.50	GO:0090315	negative regulation of protein targeting to membrane
0.48	GO:1901381	positive regulation of potassium ion transmembrane transport

0.78	GO:0005249	voltage-gated potassium channel activity
0.68	GO:0015459	potassium channel regulator activity
0.45	GO:0044325	ion channel binding
0.45	GO:0031433	telethonin binding
0.42	GO:0046982	protein heterodimerization activity

0.64	GO:0016324	apical plasma membrane
0.53	GO:0045121	membrane raft
0.53	GO:0008076	voltage-gated potassium channel complex
0.48	GO:0030018	Z disc
0.42	GO:0005764	lysosome
0.41	GO:0005794	Golgi apparatus
0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0009986	cell surface

sp|P15391|CD19_HUMAN
B-lymphocyte antigen CD19
Search

CD19

0.97	B cell surface marker CD19

0.71	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.70	GO:0050853	B cell receptor signaling pathway
0.55	GO:0006968	cellular defense response
0.41	GO:0030449	regulation of complement activation
0.41	GO:0051897	positive regulation of protein kinase B signaling
0.39	GO:0046854	phosphatidylinositol phosphorylation

0.50	GO:0005057	signal transducer activity, downstream of receptor
0.42	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.38	GO:0005515	protein binding

0.67	GO:0009897	external side of plasma membrane
0.51	GO:0043234	protein complex
0.42	GO:0070062	extracellular exosome
0.37	GO:0005887	integral component of plasma membrane

0.42	EC:2.7.1.153	GO:0046934
0.42	KEGG:R04545	GO:0046934

sp|P15407|FOSL1_HUMAN
Fos-related antigen 1
Search

FOSL1

0.66	FosB proto-oncogene, AP-1 transcription factor subunit

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.65	GO:0007296	vitellogenesis
0.65	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.63	GO:0060674	placenta blood vessel development
0.61	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.59	GO:0001701	in utero embryonic development
0.54	GO:0031668	cellular response to extracellular stimulus
0.47	GO:0051412	response to corticosterone
0.47	GO:0071277	cellular response to calcium ion
0.46	GO:0032570	response to progesterone

0.62	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding
0.32	GO:0005509	calcium ion binding

0.60	GO:0005634	nucleus
0.54	GO:0031974	membrane-enclosed lumen
0.48	GO:0044446	intracellular organelle part
0.44	GO:0042734	presynaptic membrane
0.42	GO:0043005	neuron projection
0.40	GO:0005829	cytosol
0.33	GO:0005667	transcription factor complex
0.32	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P15408|FOSL2_HUMAN
Fos-related antigen 2
Search

FOSL2

0.97	FOS like 2, AP-1 transcription factor subunit

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0003334	keratinocyte development
0.57	GO:0048146	positive regulation of fibroblast proliferation
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0045595	regulation of cell differentiation
0.45	GO:2000026	regulation of multicellular organismal development
0.45	GO:0035994	response to muscle stretch
0.44	GO:0071277	cellular response to calcium ion
0.44	GO:0035914	skeletal muscle cell differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0003682	chromatin binding
0.45	GO:0070412	R-SMAD binding
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.44	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.43	GO:0001046	core promoter sequence-specific DNA binding
0.42	GO:0000987	proximal promoter sequence-specific DNA binding
0.41	GO:0046982	protein heterodimerization activity

0.52	GO:0005654	nucleoplasm
0.45	GO:0035976	transcription factor AP-1 complex
0.40	GO:0032993	protein-DNA complex
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0005829	cytosol
0.35	GO:0070552	BRISC complex
0.35	GO:0070531	BRCA1-A complex
0.34	GO:0043005	neuron projection
0.32	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P15421|GLPE_HUMAN
Glycophorin-E
Search

0.90	Glycophorin B Miltenberger subtype III

0.38	GO:0050900	leukocyte migration
0.34	GO:0030260	entry into host cell
0.34	GO:0019058	viral life cycle

0.38	GO:0005515	protein binding
0.36	GO:0104005	hijacked molecular function

0.37	GO:0005887	integral component of plasma membrane
0.35	GO:0070062	extracellular exosome

sp|P15428|PGDH_HUMAN
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
Search

HPGD

0.86	NAD+-dependent 15-hydoxyprostaglandin dehydrogenase

0.66	GO:0097070	ductus arteriosus closure
0.65	GO:0007567	parturition
0.62	GO:0006692	prostanoid metabolic process
0.60	GO:0007179	transforming growth factor beta receptor signaling pathway
0.60	GO:0007565	female pregnancy
0.57	GO:0045786	negative regulation of cell cycle
0.53	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0055114	oxidation-reduction process
0.48	GO:0030728	ovulation
0.40	GO:1904707	positive regulation of vascular smooth muscle cell proliferation

0.67	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity
0.63	GO:0004957	prostaglandin E receptor activity
0.57	GO:0070403	NAD+ binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0004022	alcohol dehydrogenase (NAD) activity
0.36	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.34	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.34	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.34	GO:0019152	acetoin dehydrogenase activity
0.34	GO:0009010	sorbitol-6-phosphate 2-dehydrogenase activity

0.59	GO:0016323	basolateral plasma membrane
0.52	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.37	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.33	GO:0005882	intermediate filament
0.30	GO:0016021	integral component of membrane

0.67	EC:1.1.1.141	GO:0016404
0.34	KEGG:R02343	GO:0019152

sp|P15498|VAV_HUMAN
Proto-oncogene vav
Search

VAV1

0.93	Vav 3 guanine nucleotide exchange factor b

0.77	GO:0035023	regulation of Rho protein signal transduction
0.70	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.56	GO:0030593	neutrophil chemotaxis
0.55	GO:0008361	regulation of cell size
0.54	GO:0050778	positive regulation of immune response
0.53	GO:0007229	integrin-mediated signaling pathway
0.51	GO:0045785	positive regulation of cell adhesion
0.51	GO:0002768	immune response-regulating cell surface receptor signaling pathway
0.51	GO:0030890	positive regulation of B cell proliferation

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.56	GO:0048365	Rac GTPase binding
0.52	GO:0046872	metal ion binding
0.49	GO:0005154	epidermal growth factor receptor binding
0.49	GO:0001784	phosphotyrosine residue binding
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005070	SH3/SH2 adaptor activity
0.34	GO:0005096	GTPase activator activity
0.34	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005911	cell-cell junction
0.45	GO:0005622	intracellular
0.39	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|P15502|ELN_HUMAN
Elastin
Search

ELN

0.97

Elastin

0.58	GO:0043149	stress fiber assembly
0.56	GO:0030198	extracellular matrix organization
0.55	GO:0007519	skeletal muscle tissue development
0.52	GO:0030833	regulation of actin filament polymerization
0.43	GO:0007585	respiratory gaseous exchange
0.41	GO:0008015	blood circulation
0.41	GO:0008283	cell proliferation
0.41	GO:0071298	cellular response to L-ascorbic acid
0.40	GO:0009887	animal organ morphogenesis
0.40	GO:0022411	cellular component disassembly

0.82	GO:0005201	extracellular matrix structural constituent
0.55	GO:0050840	extracellular matrix binding
0.40	GO:0005515	protein binding
0.39	GO:0097493	structural molecule activity conferring elasticity
0.36	GO:0016740	transferase activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.63	GO:0071953	elastic fiber
0.44	GO:0005739	mitochondrion
0.37	GO:0005615	extracellular space

0.36

GO:0016740

sp|P15509|CSF2R_HUMAN
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
Search

CSF2RA

0.97	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha

0.78	GO:0019221	cytokine-mediated signaling pathway
0.40	GO:0000165	MAPK cascade
0.39	GO:0018108	peptidyl-tyrosine phosphorylation
0.37	GO:0065009	regulation of molecular function

0.80	GO:0004896	cytokine receptor activity
0.39	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.39	GO:0004713	protein tyrosine kinase activity

0.37	GO:0005887	integral component of plasma membrane
0.37	GO:0005576	extracellular region
0.33	GO:0005622	intracellular

0.39

GO:0004713

sp|P15514|AREG_HUMAN
Amphiregulin
Search

AREG

0.97	Amphiregulin short form

0.70	GO:0060598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
0.68	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation
0.67	GO:0060744	mammary gland branching involved in thelarche
0.66	GO:0007173	epidermal growth factor receptor signaling pathway
0.66	GO:0060749	mammary gland alveolus development
0.65	GO:0032355	response to estradiol
0.65	GO:0045740	positive regulation of DNA replication
0.63	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.61	GO:0008284	positive regulation of cell proliferation
0.55	GO:0007186	G-protein coupled receptor signaling pathway

0.54	GO:0005154	epidermal growth factor receptor binding
0.50	GO:0008083	growth factor activity
0.41	GO:0005125	cytokine activity

0.58	GO:0009986	cell surface
0.57	GO:0005615	extracellular space
0.49	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.37	GO:0012506	vesicle membrane
0.36	GO:0097708	intracellular vesicle
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment

sp|P15515|HIS1_HUMAN
Histatin-1
Search

0.97	Histidine-rich protein 3

0.78	GO:0042742	defense response to bacterium
0.52	GO:0031214	biomineral tissue development
0.50	GO:0050832	defense response to fungus
0.50	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.49	GO:0031640	killing of cells of other organism

0.42	GO:0005515	protein binding
0.36	GO:0046872	metal ion binding

0.66

GO:0005576

extracellular region

sp|P15516|HIS3_HUMAN
Histatin-3
Search

0.97	Histidine-rich protein 3

0.78	GO:0042742	defense response to bacterium
0.51	GO:0031214	biomineral tissue development
0.49	GO:0050832	defense response to fungus
0.49	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.48	GO:0031640	killing of cells of other organism

0.41	GO:0005515	protein binding
0.36	GO:0046872	metal ion binding

0.66

GO:0005576

extracellular region

sp|P15529|MCP_HUMAN
Membrane cofactor protein
Search

CD46

0.97	membrane cofactor protein isoform X2

0.79	GO:0007338	single fertilization
0.55	GO:0002449	lymphocyte mediated immunity
0.55	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
0.53	GO:0043382	positive regulation of memory T cell differentiation
0.53	GO:0032613	interleukin-10 production
0.52	GO:0035581	sequestering of extracellular ligand from receptor
0.52	GO:0045591	positive regulation of regulatory T cell differentiation
0.52	GO:0071636	positive regulation of transforming growth factor beta production
0.51	GO:0032733	positive regulation of interleukin-10 production
0.50	GO:0042102	positive regulation of T cell proliferation

0.48	GO:0045296	cadherin binding
0.41	GO:0104005	hijacked molecular function
0.37	GO:0001848	complement binding
0.37	GO:0004175	endopeptidase activity
0.37	GO:0004872	receptor activity
0.35	GO:0004857	enzyme inhibitor activity

0.85	GO:0002079	inner acrosomal membrane
0.75	GO:0009986	cell surface
0.43	GO:0005576	extracellular region
0.41	GO:0005925	focal adhesion
0.39	GO:0005886	plasma membrane
0.35	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|P15531|NDKA_HUMAN
Nucleoside diphosphate kinase A
Search

0.46	Nucleoside diphosphate kinase A

0.78	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.48	GO:0050679	positive regulation of epithelial cell proliferation
0.48	GO:0042981	regulation of apoptotic process
0.47	GO:0007595	lactation
0.46	GO:0043388	positive regulation of DNA binding
0.44	GO:2000026	regulation of multicellular organismal development
0.42	GO:0045597	positive regulation of cell differentiation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0043024	ribosomal small subunit binding
0.43	GO:0042802	identical protein binding
0.42	GO:0004536	deoxyribonuclease activity
0.41	GO:0019215	intermediate filament binding
0.40	GO:0019001	guanyl nucleotide binding

0.50	GO:0001726	ruffle
0.47	GO:0043209	myelin sheath
0.45	GO:0031256	leading edge membrane
0.45	GO:0031253	cell projection membrane
0.43	GO:0030027	lamellipodium
0.43	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005925	focal adhesion
0.40	GO:0005739	mitochondrion
0.39	GO:0070062	extracellular exosome

0.79

EC:2.7.4.6

GO:0004550

sp|P15538|C11B1_HUMAN
Cytochrome P450 11B1, mitochondrial
Search

0.81	Cholesterol side-chain cleavage enzyme, mitochondrial

0.67	GO:0006700	C21-steroid hormone biosynthetic process
0.62	GO:0032341	aldosterone metabolic process
0.61	GO:0006705	mineralocorticoid biosynthetic process
0.61	GO:0034650	cortisol metabolic process
0.55	GO:0006704	glucocorticoid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0046184	aldehyde biosynthetic process
0.51	GO:0002017	regulation of blood volume by renal aldosterone
0.51	GO:1901617	organic hydroxy compound biosynthetic process
0.51	GO:0042181	ketone biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0008395	steroid hydroxylase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0005496	steroid binding
0.33	GO:0004743	pyruvate kinase activity
0.33	GO:0030955	potassium ion binding
0.32	GO:0000287	magnesium ion binding
0.32	GO:0016301	kinase activity

0.54	GO:0005739	mitochondrion
0.46	GO:0031967	organelle envelope
0.46	GO:0031090	organelle membrane
0.35	GO:0030425	dendrite
0.35	GO:0030176	integral component of endoplasmic reticulum membrane

0.68