Queries 20001 to 21000

GO:0016874

sp|Q9UKV8|AGO2_HUMAN
Protein argonaute-2
Search

0.10	Eukaryotic translation initiation factor 2C 2 (Fragment)

0.78	GO:0031047	gene silencing by RNA
0.78	GO:0098795	mRNA cleavage involved in gene silencing
0.78	GO:0040033	negative regulation of translation, ncRNA-mediated
0.75	GO:0031050	dsRNA fragmentation
0.75	GO:0016441	posttranscriptional gene silencing
0.70	GO:0045947	negative regulation of translational initiation
0.62	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.58	GO:0034470	ncRNA processing
0.57	GO:1905616	regulation of miRNA mediated inhibition of translation
0.56	GO:0010501	RNA secondary structure unwinding

0.81	GO:0070551	endoribonuclease activity, cleaving siRNA-paired mRNA
0.78	GO:0035198	miRNA binding
0.76	GO:0035197	siRNA binding
0.74	GO:0000340	RNA 7-methylguanosine cap binding
0.57	GO:0090624	endoribonuclease activity, cleaving miRNA-paired mRNA
0.54	GO:0003727	single-stranded RNA binding
0.54	GO:0098808	mRNA cap binding
0.53	GO:0000993	RNA polymerase II core binding
0.53	GO:0003725	double-stranded RNA binding
0.52	GO:0001047	core promoter binding

0.79	GO:0035068	micro-ribonucleoprotein complex
0.78	GO:0016442	RISC complex
0.74	GO:0005845	mRNA cap binding complex
0.73	GO:0000932	P-body
0.61	GO:0070578	RISC-loading complex
0.53	GO:0005844	polysome
0.51	GO:0070062	extracellular exosome
0.50	GO:0030425	dendrite
0.50	GO:0005634	nucleus
0.48	GO:0030054	cell junction

sp|Q9UKW4|VAV3_HUMAN
Guanine nucleotide exchange factor VAV3
Search

VAV3

0.91	Vav 3 guanine nucleotide exchange factor b

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0030890	positive regulation of B cell proliferation
0.56	GO:0050853	B cell receptor signaling pathway
0.55	GO:0030032	lamellipodium assembly
0.55	GO:0030593	neutrophil chemotaxis
0.55	GO:1903727	positive regulation of phospholipid metabolic process
0.54	GO:0008361	regulation of cell size
0.53	GO:0006906	vesicle fusion

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.55	GO:0005154	epidermal growth factor receptor binding
0.55	GO:0048365	Rac GTPase binding
0.51	GO:0046872	metal ion binding
0.35	GO:0005070	SH3/SH2 adaptor activity
0.34	GO:0005096	GTPase activator activity

0.45	GO:0005622	intracellular
0.41	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9UKW6|ELF5_HUMAN
ETS-related transcription factor Elf-5
Search

ELF5

0.97	Epithelium specific ETS transcription factor ESE-2 homolog

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.69	GO:0001712	ectodermal cell fate commitment
0.65	GO:0035019	somatic stem cell population maintenance
0.65	GO:0060644	mammary gland epithelial cell differentiation
0.61	GO:0045596	negative regulation of cell differentiation
0.59	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0008283	cell proliferation
0.36	GO:0001709	cell fate determination
0.34	GO:0045892	negative regulation of transcription, DNA-templated

0.72	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm

sp|Q9UKX2|MYH2_HUMAN
Myosin-2
Search

0.77	Myosin, heavy polypeptide 8, skeletal muscle, perinatal

0.74	GO:0007018	microtubule-based movement
0.57	GO:0006936	muscle contraction
0.55	GO:0070252	actin-mediated cell contraction
0.53	GO:0014823	response to activity
0.50	GO:0050881	musculoskeletal movement
0.45	GO:0001778	plasma membrane repair
0.42	GO:0046034	ATP metabolic process
0.38	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.77	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005516	calmodulin binding
0.42	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.49	GO:0014704	intercalated disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0005826	actomyosin contractile ring
0.40	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.42

GO:0016887

sp|Q9UKX3|MYH13_HUMAN
Myosin-13
Search

0.69	Skeletal muscle myosin heavy chain MyHC-EO/IIL

0.74	GO:0007018	microtubule-based movement
0.53	GO:0006936	muscle contraction
0.51	GO:0033275	actin-myosin filament sliding
0.48	GO:0050881	musculoskeletal movement
0.46	GO:0014823	response to activity
0.42	GO:0009267	cellular response to starvation
0.41	GO:0046034	ATP metabolic process
0.37	GO:0001778	plasma membrane repair
0.37	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.77	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0000146	microfilament motor activity
0.45	GO:0005516	calmodulin binding
0.41	GO:0016887	ATPase activity
0.37	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.55	GO:0043292	contractile fiber
0.44	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0014704	intercalated disc
0.36	GO:0005826	actomyosin contractile ring
0.35	GO:0005829	cytosol
0.35	GO:0005794	Golgi apparatus
0.35	GO:0070062	extracellular exosome
0.34	GO:0005882	intermediate filament

0.41

GO:0016887

sp|Q9UKX5|ITA11_HUMAN
Integrin alpha-11
Search

ITGA11

0.97	Integrin subunit alpha 11

0.79	GO:0007229	integrin-mediated signaling pathway
0.71	GO:0007155	cell adhesion
0.59	GO:0006929	substrate-dependent cell migration
0.58	GO:0038065	collagen-activated signaling pathway
0.39	GO:0001649	osteoblast differentiation
0.36	GO:0007517	muscle organ development
0.36	GO:0030198	extracellular matrix organization

0.61	GO:0098639	collagen binding involved in cell-matrix adhesion
0.58	GO:0038064	collagen receptor activity
0.34	GO:0046872	metal ion binding

0.80	GO:0008305	integrin complex
0.55	GO:0005925	focal adhesion

sp|Q9UKX7|NUP50_HUMAN
Nuclear pore complex protein Nup50
Search

NUP50

0.86	Nucleoporin 50 kDa

0.68	GO:0046907	intracellular transport
0.51	GO:0006606	protein import into nucleus

0.51

GO:0008536

Ran GTPase binding

0.76	GO:0005643	nuclear pore
0.64	GO:0031965	nuclear membrane
0.58	GO:0005654	nucleoplasm

sp|Q9UKY0|PRND_HUMAN
Prion-like protein doppel
Search

PRND

0.97	Prion like protein doppel

0.75	GO:0051260	protein homooligomerization
0.44	GO:0006878	cellular copper ion homeostasis
0.41	GO:0007340	acrosome reaction
0.36	GO:0006501	C-terminal protein lipidation
0.35	GO:0007283	spermatogenesis

0.52	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.55	GO:0031362	anchored component of external side of plasma membrane
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q9UKY1|ZHX1_HUMAN
Zinc fingers and homeoboxes protein 1
Search

ZHX1

0.96	Zinc fingers and homeoboxes protein 1

0.61	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated
0.35	GO:0030154	cell differentiation

0.62	GO:0003714	transcription corepressor activity
0.58	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.50	GO:0046872	metal ion binding
0.50	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.52	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UKY3|CES1P_HUMAN
Putative inactive carboxylesterase 4
Search

0.70	Liver carboxylesterase 22

0.55	GO:0051791	medium-chain fatty acid metabolic process
0.54	GO:0034377	plasma lipoprotein particle assembly
0.53	GO:0006695	cholesterol biosynthetic process
0.51	GO:0030855	epithelial cell differentiation
0.50	GO:0019626	short-chain fatty acid catabolic process
0.49	GO:0046464	acylglycerol catabolic process
0.49	GO:0090122	cholesterol ester hydrolysis involved in cholesterol transport
0.46	GO:0090320	regulation of chylomicron remnant clearance
0.43	GO:0009636	response to toxic substance
0.43	GO:0090207	regulation of triglyceride metabolic process

0.68	GO:0052689	carboxylic ester hydrolase activity
0.49	GO:0016298	lipase activity
0.44	GO:0016290	palmitoyl-CoA hydrolase activity
0.42	GO:0019213	deacetylase activity

0.75	GO:0005788	endoplasmic reticulum lumen
0.51	GO:0005811	lipid droplet
0.48	GO:0005829	cytosol
0.43	GO:0005576	extracellular region

0.68	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.68	KEGG:R00630	GO:0052689

sp|Q9UKY4|POMT2_HUMAN
Protein O-mannosyl-transferase 2
Search

POMT2

0.97	Protein O-mannosyl-transferase 2 isoform B

0.76	GO:0006493	protein O-linked glycosylation
0.74	GO:0097502	mannosylation
0.51	GO:0071712	ER-associated misfolded protein catabolic process
0.41	GO:1904098	regulation of protein O-linked glycosylation
0.40	GO:0060050	positive regulation of protein glycosylation
0.37	GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system
0.37	GO:0015671	oxygen transport
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.75	GO:0000030	mannosyltransferase activity
0.37	GO:0005344	oxygen carrier activity
0.35	GO:0020037	heme binding
0.34	GO:0046872	metal ion binding
0.33	GO:0003735	structural constituent of ribosome

0.45	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.75

GO:0000030

sp|Q9UKY7|CDV3_HUMAN
Protein CDV3 homolog
Search

0.41	GO:0008283	cell proliferation
0.39	GO:0045104	intermediate filament cytoskeleton organization
0.39	GO:0043525	positive regulation of neuron apoptotic process
0.38	GO:0050796	regulation of insulin secretion
0.37	GO:0008285	negative regulation of cell proliferation
0.37	GO:0008284	positive regulation of cell proliferation
0.37	GO:0043066	negative regulation of apoptotic process
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0045595	regulation of cell differentiation
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II

0.36	GO:0046983	protein dimerization activity
0.35	GO:0005198	structural molecule activity
0.35	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity

0.62	GO:0005829	cytosol
0.51	GO:0005886	plasma membrane
0.38	GO:0005634	nucleus
0.38	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UKZ1|CNO11_HUMAN
CCR4-NOT transcription complex subunit 11
Search

CNOT11

0.97	CCR4-NOT transcription complex subunit 11

0.40	GO:0031047	gene silencing by RNA
0.39	GO:0006417	regulation of translation
0.37	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.36	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0008283	cell proliferation

0.34

GO:0005515

protein binding

0.79	GO:0030014	CCR4-NOT complex
0.37	GO:0005634	nucleus
0.34	GO:0005829	cytosol

sp|Q9UKZ4|TEN1_HUMAN
Teneurin-1
Search

TENM1

0.96	Teneurin transmembrane protein 1

0.77	GO:0048666	neuron development
0.58	GO:0007165	signal transduction
0.51	GO:0097264	self proteolysis
0.48	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.45	GO:0032989	cellular component morphogenesis
0.39	GO:0060912	cardiac cell fate specification
0.39	GO:0051491	positive regulation of filopodium assembly
0.39	GO:0031643	positive regulation of myelination
0.39	GO:2000543	positive regulation of gastrulation
0.39	GO:0048714	positive regulation of oligodendrocyte differentiation

0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.46	GO:0050839	cell adhesion molecule binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0008201	heparin binding
0.30	GO:0003824	catalytic activity

0.47	GO:0005887	integral component of plasma membrane
0.46	GO:0043005	neuron projection
0.39	GO:0016363	nuclear matrix
0.38	GO:0016607	nuclear speck
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005856	cytoskeleton
0.35	GO:0005576	extracellular region

sp|Q9UKZ9|PCOC2_HUMAN
Procollagen C-endopeptidase enhancer 2
Search

PCOLCE2

0.97	Procollagen C-endopeptidase enhancer b

0.65	GO:0010952	positive regulation of peptidase activity
0.59	GO:1990823	response to leukemia inhibitory factor
0.56	GO:0071345	cellular response to cytokine stimulus

0.66	GO:0016504	peptidase activator activity
0.65	GO:0005518	collagen binding
0.65	GO:0008201	heparin binding

0.66	GO:0005576	extracellular region
0.41	GO:0005581	collagen trimer
0.36	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|Q9UL01|DSE_HUMAN
Dermatan-sulfate epimerase
Search

DSE

0.97	Dermatan-sulfate epimerase

0.61	GO:0030208	dermatan sulfate biosynthetic process
0.40	GO:0030204	chondroitin sulfate metabolic process
0.39	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.39	GO:0015012	heparan sulfate proteoglycan biosynthetic process

0.63	GO:0047757	chondroitin-glucuronate 5-epimerase activity
0.40	GO:0008146	sulfotransferase activity

0.51	GO:0005794	Golgi apparatus
0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.63

EC:5.1.3.19

GO:0047757

sp|Q9UL03|INT6_HUMAN
Integrator complex subunit 6
Search

INTS6

0.95	Integrator complex subunit 6-A

0.79	GO:0016180	snRNA processing
0.41	GO:0042795	snRNA transcription by RNA polymerase II
0.36	GO:0007165	signal transduction

0.37	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.79	GO:0032039	integrator complex
0.72	GO:0015629	actin cytoskeleton

sp|Q9UL12|SARDH_HUMAN
Sarcosine dehydrogenase, mitochondrial
Search

SARDH

0.77	Sarcosine dehydrogenase

0.53	GO:1901053	sarcosine catabolic process
0.52	GO:0055114	oxidation-reduction process
0.38	GO:0042426	choline catabolic process
0.36	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0065009	regulation of molecular function
0.35	GO:0035556	intracellular signal transduction
0.34	GO:0006545	glycine biosynthetic process
0.34	GO:0035999	tetrahydrofolate interconversion
0.32	GO:0006091	generation of precursor metabolites and energy

0.53	GO:0008480	sarcosine dehydrogenase activity
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.35	GO:0005542	folic acid binding
0.34	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0046872	metal ion binding
0.33	GO:0009055	electron transfer activity

0.47	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:1.5.8.3	GO:0008480
0.53	KEGG:R00611	GO:0008480

sp|Q9UL15|BAG5_HUMAN
BAG family molecular chaperone regulator 5
Search

BAG5

0.96	LOW QUALITY PROTEIN: BAG family molecular chaperone regulator 5

0.51	GO:0090083	regulation of inclusion body assembly
0.51	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.50	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.49	GO:0031397	negative regulation of protein ubiquitination
0.49	GO:0010977	negative regulation of neuron projection development
0.48	GO:0007030	Golgi organization
0.46	GO:0061084	negative regulation of protein refolding
0.43	GO:0070997	neuron death
0.42	GO:0051438	regulation of ubiquitin-protein transferase activity
0.41	GO:0051348	negative regulation of transferase activity

0.77	GO:0051087	chaperone binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0019901	protein kinase binding
0.37	GO:0000774	adenyl-nucleotide exchange factor activity

0.49	GO:0016234	inclusion body
0.47	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q9UL16|CFA45_HUMAN
Cilia- and flagella-associated protein 45
Search

CFAP45

0.87	Coiled-coil domain-containing protein 19, mitochondrial

0.37	GO:0006886	intracellular protein transport
0.35	GO:0022613	ribonucleoprotein complex biogenesis
0.34	GO:0002183	cytoplasmic translational initiation
0.34	GO:0071826	ribonucleoprotein complex subunit organization
0.34	GO:0006446	regulation of translational initiation
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0034622	cellular macromolecular complex assembly
0.33	GO:0034470	ncRNA processing
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0006351	transcription, DNA-templated

0.39	GO:0017137	Rab GTPase binding
0.34	GO:0008408	3'-5' exonuclease activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0003743	translation initiation factor activity
0.34	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003729	mRNA binding

0.62	GO:0005654	nucleoplasm
0.56	GO:0031514	motile cilium
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0000801	central element
0.33	GO:0000800	lateral element
0.33	GO:0010369	chromocenter
0.33	GO:0005721	pericentric heterochromatin
0.33	GO:0015630	microtubule cytoskeleton

sp|Q9UL17|TBX21_HUMAN
T-box transcription factor TBX21
Search

0.90	T-box brain protein 1

0.62	GO:2000329	negative regulation of T-helper 17 cell lineage commitment
0.62	GO:2000552	negative regulation of T-helper 2 cell cytokine production
0.60	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.60	GO:0032703	negative regulation of interleukin-2 production
0.60	GO:0072676	lymphocyte migration
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0030217	T cell differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0043565	sequence-specific DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.38	GO:0005515	protein binding
0.35	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.34	GO:0003682	chromatin binding
0.32	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.55	GO:0043025	neuronal cell body
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q9UL18|AGO1_HUMAN
Protein argonaute-1
Search

AGO1

0.95	Argonaute RISC catalytic component 1

0.79	GO:0031047	gene silencing by RNA
0.59	GO:0040033	negative regulation of translation, ncRNA-mediated
0.57	GO:0016441	posttranscriptional gene silencing
0.57	GO:0010586	miRNA metabolic process
0.56	GO:0031050	dsRNA fragmentation
0.55	GO:0010501	RNA secondary structure unwinding
0.53	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.52	GO:0016525	negative regulation of angiogenesis
0.51	GO:0006402	mRNA catabolic process
0.51	GO:0022618	ribonucleoprotein complex assembly

0.60	GO:0035198	miRNA binding
0.53	GO:0003727	single-stranded RNA binding
0.53	GO:0000993	RNA polymerase II core binding
0.52	GO:0003725	double-stranded RNA binding
0.52	GO:0001047	core promoter binding
0.50	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0003743	translation initiation factor activity
0.35	GO:0004521	endoribonuclease activity

0.60	GO:0035068	micro-ribonucleoprotein complex
0.58	GO:0070578	RISC-loading complex
0.58	GO:0016442	RISC complex
0.56	GO:0000932	P-body
0.51	GO:0005844	polysome
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.40	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.35	GO:0000793	condensed chromosome

sp|Q9UL19|HRSL4_HUMAN
Retinoic acid receptor responder protein 3
Search

PLA2G16

0.94	Retinoic acid receptor responder protein 3

0.54	GO:0008285	negative regulation of cell proliferation
0.52	GO:0006644	phospholipid metabolic process
0.47	GO:1904177	regulation of adipose tissue development
0.45	GO:0046485	ether lipid metabolic process
0.45	GO:0046486	glycerolipid metabolic process
0.44	GO:0006638	neutral lipid metabolic process
0.43	GO:0007031	peroxisome organization
0.42	GO:0016042	lipid catabolic process
0.39	GO:0008610	lipid biosynthetic process
0.38	GO:0090407	organophosphate biosynthetic process

0.59	GO:0004623	phospholipase A2 activity
0.45	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.40	GO:0016746	transferase activity, transferring acyl groups
0.39	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.39	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.39	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity
0.39	GO:0052739	phosphatidylserine 1-acylhydrolase activity
0.35	GO:0005515	protein binding
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding

0.43	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005777	peroxisome
0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0031903	microbody membrane
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.59	EC:3.1.1.4	GO:0004623
0.39	KEGG:R04034	GO:0052739

sp|Q9UL25|RAB21_HUMAN
Ras-related protein Rab-21
Search

RAB21

0.95	RAB21, member RAS oncogene family

0.54	GO:2000643	positive regulation of early endosome to late endosome transport
0.54	GO:0030100	regulation of endocytosis
0.53	GO:0050775	positive regulation of dendrite morphogenesis
0.50	GO:0017157	regulation of exocytosis
0.41	GO:0008089	anterograde axonal transport
0.40	GO:0030516	regulation of axon extension
0.37	GO:0015031	protein transport
0.32	GO:0043547	positive regulation of GTPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding
0.32	GO:0005096	GTPase activator activity

0.55	GO:0098559	cytoplasmic side of early endosome membrane
0.50	GO:0032580	Golgi cisterna membrane
0.49	GO:0005802	trans-Golgi network
0.49	GO:0012506	vesicle membrane
0.49	GO:0043005	neuron projection
0.48	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0097610	cell surface furrow
0.40	GO:0032155	cell division site part
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.38	GO:0005789	endoplasmic reticulum membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|Q9UL26|RB22A_HUMAN
Ras-related protein Rab-22A
Search

RAB22A

0.97	Ras-related protein Rab-22A isoform B

0.58	GO:0097494	regulation of vesicle size
0.54	GO:0007032	endosome organization
0.53	GO:0006897	endocytosis
0.46	GO:0043001	Golgi to plasma membrane protein transport
0.45	GO:0090382	phagosome maturation
0.45	GO:0032869	cellular response to insulin stimulus
0.44	GO:0045055	regulated exocytosis
0.44	GO:0043112	receptor metabolic process
0.34	GO:0002283	neutrophil activation involved in immune response
0.34	GO:0002446	neutrophil mediated immunity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0015035	protein disulfide oxidoreductase activity

0.58	GO:0045335	phagocytic vesicle
0.58	GO:0005769	early endosome
0.49	GO:0015629	actin cytoskeleton
0.46	GO:0032588	trans-Golgi network membrane
0.42	GO:0005886	plasma membrane
0.40	GO:0030666	endocytic vesicle membrane
0.38	GO:0005770	late endosome
0.38	GO:0010008	endosome membrane
0.38	GO:0001726	ruffle
0.37	GO:0070062	extracellular exosome

sp|Q9UL33|TPC2L_HUMAN
Trafficking protein particle complex subunit 2-like protein
Search

TRAPPC2L

0.93	Trafficking protein particle complex 2 like

0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.36	GO:0051259	protein oligomerization
0.35	GO:0006901	vesicle coating
0.35	GO:0048199	vesicle targeting, to, from or within Golgi
0.35	GO:0048194	Golgi vesicle budding
0.33	GO:0065009	regulation of molecular function

0.35

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.49	GO:0005737	cytoplasm
0.43	GO:0030008	TRAPP complex
0.41	GO:0043227	membrane-bounded organelle
0.40	GO:0043229	intracellular organelle
0.38	GO:0012505	endomembrane system
0.33	GO:0044422	organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UL36|ZN236_HUMAN
Zinc finger protein 236
Search

ZNF236

0.72	zinc finger protein 236

0.35	GO:0071333	cellular response to glucose stimulus
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.43	GO:0008270	zinc ion binding

0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9UL40|ZN346_HUMAN
Zinc finger protein 346
Search

ZNF346

0.62	Zinc finger domain-containing protein (Fragment)

0.55	GO:0043065	positive regulation of apoptotic process
0.50	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.35	GO:0018108	peptidyl-tyrosine phosphorylation

0.63	GO:0008270	zinc ion binding
0.59	GO:0035198	miRNA binding
0.55	GO:0003725	double-stranded RNA binding
0.51	GO:0019899	enzyme binding
0.50	GO:0002039	p53 binding
0.35	GO:0004713	protein tyrosine kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0005730	nucleolus
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.7.10

GO:0004713

sp|Q9UL41|PNMA3_HUMAN
Paraneoplastic antigen Ma3
Search

0.96	Paraneoplastic Ma antigen 3

0.42	GO:0043065	positive regulation of apoptotic process
0.38	GO:0002437	inflammatory response to antigenic stimulus

0.59	GO:0008270	zinc ion binding
0.49	GO:0003676	nucleic acid binding
0.44	GO:0042802	identical protein binding

0.48	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm

sp|Q9UL42|PNMA2_HUMAN
Paraneoplastic antigen Ma2
Search

0.97	Paraneoplastic Ma antigen 2

0.53	GO:0002437	inflammatory response to antigenic stimulus
0.44	GO:0043065	positive regulation of apoptotic process

0.45

GO:0005515

protein binding

0.71	GO:0005730	nucleolus
0.45	GO:0005737	cytoplasm

sp|Q9UL45|BL1S6_HUMAN
Biogenesis of lysosome-related organelles complex 1 subunit 6
Search

BLOC1S6

0.96	Biogenesis of lysosome-related organelles complex 1 subunit 6

0.82	GO:0033299	secretion of lysosomal enzymes
0.81	GO:0048490	anterograde synaptic vesicle transport
0.80	GO:0032816	positive regulation of natural killer cell activation
0.79	GO:0050931	pigment cell differentiation
0.73	GO:0007596	blood coagulation
0.71	GO:0031175	neuron projection development
0.62	GO:0061025	membrane fusion
0.53	GO:0050942	positive regulation of pigment cell differentiation
0.53	GO:0043482	cellular pigment accumulation
0.52	GO:0032402	melanosome transport

0.48	GO:0051015	actin filament binding
0.47	GO:0042803	protein homodimerization activity
0.41	GO:0019905	syntaxin binding

0.83	GO:0031083	BLOC-1 complex
0.78	GO:1904115	axon cytoplasm
0.72	GO:0031410	cytoplasmic vesicle
0.67	GO:0012505	endomembrane system
0.62	GO:0019898	extrinsic component of membrane
0.50	GO:0031201	SNARE complex
0.40	GO:0098793	presynapse

sp|Q9UL46|PSME2_HUMAN
Proteasome activator complex subunit 2
Search

PSME2

0.97	Proteasome activator complex subunit 2

0.49	GO:0010950	positive regulation of endopeptidase activity
0.48	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.46	GO:0061136	regulation of proteasomal protein catabolic process
0.42	GO:0019884	antigen processing and presentation of exogenous antigen
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0035722	interleukin-12-mediated signaling pathway
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation

0.51	GO:0061133	endopeptidase activator activity
0.46	GO:0042802	identical protein binding
0.33	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.32	GO:0005525	GTP binding
0.32	GO:0016301	kinase activity

0.85	GO:0008537	proteasome activator complex
0.37	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.33

EC:4.1.1.32

GO:0004613

sp|Q9UL49|TCFL5_HUMAN
Transcription factor-like 5 protein
Search

TCFL5

0.97	Transcription factor like 5

0.55	GO:0007283	spermatogenesis
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0042127	regulation of cell proliferation
0.51	GO:0045595	regulation of cell differentiation
0.47	GO:0006366	transcription by RNA polymerase II
0.37	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development

0.68	GO:0046983	protein dimerization activity
0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.58	GO:0001673	male germ cell nucleus
0.30	GO:0016020	membrane

sp|Q9UL51|HCN2_HUMAN
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Search

HCN2

0.86	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

0.72	GO:0071805	potassium ion transmembrane transport
0.69	GO:0034765	regulation of ion transmembrane transport
0.63	GO:0006814	sodium ion transport
0.62	GO:0002027	regulation of heart rate
0.60	GO:0071320	cellular response to cAMP
0.57	GO:0042391	regulation of membrane potential
0.56	GO:0071321	cellular response to cGMP
0.53	GO:0098659	inorganic cation import across plasma membrane
0.47	GO:0046549	retinal cone cell development
0.47	GO:0051289	protein homotetramerization

0.77	GO:0005249	voltage-gated potassium channel activity
0.69	GO:0030552	cAMP binding
0.62	GO:0005222	intracellular cAMP activated cation channel activity
0.58	GO:0005248	voltage-gated sodium channel activity
0.52	GO:0042802	identical protein binding
0.36	GO:0032403	protein complex binding
0.36	GO:0030165	PDZ domain binding
0.35	GO:0032947	protein complex scaffold activity
0.35	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.35	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.63	GO:0098855	HCN channel complex
0.46	GO:0030424	axon
0.45	GO:0036477	somatodendritic compartment
0.44	GO:0120038	plasma membrane bounded cell projection part
0.40	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0044297	cell body
0.37	GO:0098590	plasma membrane region
0.37	GO:0045202	synapse
0.37	GO:0031256	leading edge membrane
0.34	GO:0009986	cell surface

0.34

GO:0004252

sp|Q9UL52|TM11E_HUMAN
Transmembrane protease serine 11E
Search

TMPRSS11E

0.86	Transmembrane protease serine

0.59	GO:0006508	proteolysis
0.52	GO:0050890	cognition
0.40	GO:0042730	fibrinolysis
0.40	GO:0030514	negative regulation of BMP signaling pathway
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0006879	cellular iron ion homeostasis
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0040008	regulation of growth
0.34	GO:0022617	extracellular matrix disassembly
0.34	GO:0030574	collagen catabolic process

0.66	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0004222	metalloendopeptidase activity

0.60	GO:0005576	extracellular region
0.59	GO:0005887	integral component of plasma membrane
0.44	GO:0043204	perikaryon
0.43	GO:0030425	dendrite
0.34	GO:0009986	cell surface
0.33	GO:0031982	vesicle
0.31	GO:0005622	intracellular

0.66

GO:0004252

sp|Q9UL54|TAOK2_HUMAN
Serine/threonine-protein kinase TAO2
Search

TAOK2

0.97	Serine/threonine-protein kinase TAO2

0.63	GO:0140059	dendrite arborization
0.63	GO:0006468	protein phosphorylation
0.61	GO:0050775	positive regulation of dendrite morphogenesis
0.61	GO:0048041	focal adhesion assembly
0.60	GO:0007095	mitotic G2 DNA damage checkpoint
0.60	GO:0000186	activation of MAPKK activity
0.59	GO:0031098	stress-activated protein kinase signaling cascade
0.59	GO:0046330	positive regulation of JNK cascade
0.56	GO:0007409	axonogenesis
0.55	GO:0032956	regulation of actin cytoskeleton organization

0.63	GO:0004672	protein kinase activity
0.62	GO:0038191	neuropilin binding
0.61	GO:0031434	mitogen-activated protein kinase kinase binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005057	signal transducer activity, downstream of receptor
0.32	GO:0043539	protein serine/threonine kinase activator activity
0.32	GO:0031489	myosin V binding

0.64	GO:0044294	dendritic growth cone
0.61	GO:0044295	axonal growth cone
0.55	GO:0043235	receptor complex
0.53	GO:0015629	actin cytoskeleton
0.52	GO:0031410	cytoplasmic vesicle
0.52	GO:0005730	nucleolus
0.49	GO:0005829	cytosol
0.40	GO:0012506	vesicle membrane
0.32	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9UL58|ZN215_HUMAN
Zinc finger protein 215
Search

ZNF215

0.89	Zinc finger protein 215

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.34	GO:0007275	multicellular organism development
0.34	GO:1902679	negative regulation of RNA biosynthetic process

0.50	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.50	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.50	GO:0005634	nucleus
0.37	GO:0015629	actin cytoskeleton
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm

sp|Q9UL59|ZN214_HUMAN
Zinc finger protein 214
Search

0.62	Zinc finger protein 45

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.41	GO:0017053	transcriptional repressor complex
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0012505	endomembrane system
0.37	GO:0031975	envelope
0.36	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|Q9UL62|TRPC5_HUMAN
Short transient receptor potential channel 5
Search

TRPC5

0.96	Short transient receptor potential channel 5

0.76	GO:0070588	calcium ion transmembrane transport
0.48	GO:0051480	regulation of cytosolic calcium ion concentration
0.47	GO:0006828	manganese ion transport
0.45	GO:0014051	gamma-aminobutyric acid secretion
0.45	GO:0070509	calcium ion import
0.45	GO:0022008	neurogenesis
0.44	GO:1902630	regulation of membrane hyperpolarization
0.43	GO:2000171	negative regulation of dendrite development
0.42	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.42	GO:0010771	negative regulation of cell morphogenesis involved in differentiation

0.79	GO:0005262	calcium channel activity
0.61	GO:0070679	inositol 1,4,5 trisphosphate binding
0.44	GO:0008013	beta-catenin binding
0.44	GO:0045296	cadherin binding
0.42	GO:0051117	ATPase binding
0.41	GO:0042805	actinin binding
0.41	GO:0030276	clathrin binding
0.39	GO:0003779	actin binding

0.59	GO:0034704	calcium channel complex
0.46	GO:0045121	membrane raft
0.44	GO:0016323	basolateral plasma membrane
0.44	GO:0030863	cortical cytoskeleton
0.43	GO:0005911	cell-cell junction
0.42	GO:0009986	cell surface
0.42	GO:0005887	integral component of plasma membrane
0.42	GO:0030426	growth cone
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite

sp|Q9UL63|MKLN1_HUMAN
Muskelin
Search

MKLN1

0.94	Muskelin 1, intracellular mediator containing kelch motifs

0.82	GO:0007160	cell-matrix adhesion
0.77	GO:0031532	actin cytoskeleton reorganization
0.69	GO:0008360	regulation of cell shape
0.36	GO:0007165	signal transduction
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0034645	cellular macromolecule biosynthetic process

0.73	GO:0042802	identical protein binding
0.34	GO:0003735	structural constituent of ribosome

0.83	GO:0001726	ruffle
0.76	GO:0005938	cell cortex
0.68	GO:0005829	cytosol
0.34	GO:0005840	ribosome

sp|Q9UL68|MYT1L_HUMAN
Myelin transcription factor 1-like protein
Search

0.94	Myelin transcription factor 1 like

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0048665	neuron fate specification
0.42	GO:0048666	neuron development
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.30	GO:0090304	nucleic acid metabolic process
0.30	GO:0018130	heterocycle biosynthetic process
0.30	GO:1901362	organic cyclic compound biosynthetic process
0.30	GO:0019438	aromatic compound biosynthetic process

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.30	GO:1901363	heterocyclic compound binding
0.30	GO:0097159	organic cyclic compound binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane
0.30	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q9ULA0|DNPEP_HUMAN
Aspartyl aminopeptidase
Search

DNPEP

0.78	Aspartyl aminopeptidase

0.60	GO:0006508	proteolysis
0.40	GO:0006518	peptide metabolic process
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation

0.71	GO:0004177	aminopeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding
0.37	GO:0042802	identical protein binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.49	GO:0005829	cytosol
0.42	GO:0005576	extracellular region
0.34	GO:0005634	nucleus

0.71

EC:3.4.11

GO:0004177

sp|Q9ULB1|NRX1A_HUMAN
Neurexin-1
Search

NRXN1

0.87	Neurexin-1-alpha

0.49	GO:0098596	imitative learning
0.49	GO:0098598	learned vocalization behavior or vocal learning
0.49	GO:0031223	auditory behavior
0.49	GO:0071625	vocalization behavior
0.48	GO:0035176	social behavior
0.46	GO:0030534	adult behavior
0.46	GO:0097116	gephyrin clustering involved in postsynaptic density assembly
0.46	GO:0099560	synaptic membrane adhesion
0.45	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.45	GO:2000821	regulation of grooming behavior

0.46	GO:0097109	neuroligin family protein binding
0.44	GO:0033130	acetylcholine receptor binding
0.44	GO:0005246	calcium channel regulator activity
0.42	GO:0050839	cell adhesion molecule binding
0.36	GO:0005105	type 1 fibroblast growth factor receptor binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0004872	receptor activity
0.32	GO:0048306	calcium-dependent protein binding
0.31	GO:0004871	signal transducer activity

0.46	GO:0005730	nucleolus
0.44	GO:0009986	cell surface
0.44	GO:0042734	presynaptic membrane
0.42	GO:0043025	neuronal cell body
0.42	GO:0031965	nuclear membrane
0.40	GO:0031982	vesicle
0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0043234	protein complex
0.36	GO:0030054	cell junction
0.34	GO:0005887	integral component of plasma membrane

sp|Q9ULB4|CADH9_HUMAN
Cadherin-9
Search

CDH9

0.96	Kidney cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.50	GO:0007219	Notch signaling pathway
0.38	GO:0007416	synapse assembly
0.38	GO:0099560	synaptic membrane adhesion
0.36	GO:0034332	adherens junction organization
0.34	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0008585	female gonad development

0.70	GO:0005509	calcium ion binding
0.37	GO:0098641	cadherin binding involved in cell-cell adhesion
0.36	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.38	GO:0098686	hippocampal mossy fiber to CA3 synapse
0.37	GO:0097458	neuron part
0.36	GO:0098794	postsynapse
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9ULB5|CADH7_HUMAN
Cadherin-7
Search

CDH7

0.97	Cadherin-7

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.40	GO:0036032	neural crest cell delamination
0.40	GO:0009790	embryo development
0.39	GO:0048731	system development
0.38	GO:0072175	epithelial tube formation
0.37	GO:0030154	cell differentiation
0.35	GO:0098743	cell aggregation
0.35	GO:0034332	adherens junction organization
0.35	GO:0060173	limb development
0.35	GO:0061448	connective tissue development

0.70

GO:0005509

calcium ion binding

0.56	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9ULC0|MUCEN_HUMAN
Endomucin
Search

EMCN

0.97

Endomucin

0.62	GO:0001525	angiogenesis
0.59	GO:0098609	cell-cell adhesion
0.58	GO:0030155	regulation of cell adhesion

0.55

GO:0030246

carbohydrate binding

0.47	GO:0005886	plasma membrane
0.37	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q9ULC3|RAB23_HUMAN
Ras-related protein Rab-23
Search

RAB23

0.97	RAB23, member RAS oncogene family

0.58	GO:0006968	cellular defense response
0.58	GO:0097094	craniofacial suture morphogenesis
0.57	GO:0000045	autophagosome assembly
0.57	GO:0042992	negative regulation of transcription factor import into nucleus
0.53	GO:0060271	cilium assembly
0.51	GO:0046039	GTP metabolic process
0.47	GO:0035469	determination of pancreatic left/right asymmetry
0.47	GO:0071910	determination of liver left/right asymmetry
0.47	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.45	GO:0061371	determination of heart left/right asymmetry

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.58	GO:0005776	autophagosome
0.55	GO:0045335	phagocytic vesicle
0.53	GO:0005813	centrosome
0.51	GO:0030054	cell junction
0.48	GO:0005829	cytosol
0.47	GO:0010008	endosome membrane
0.42	GO:0005886	plasma membrane
0.37	GO:0030666	endocytic vesicle membrane
0.36	GO:0070062	extracellular exosome

sp|Q9ULC4|MCTS1_HUMAN
Malignant T-cell-amplified sequence 1
Search

0.10	Putative rna-binding protein (Fragment)

0.59

GO:0003723

RNA binding

0.46

GO:0005737

cytoplasm

sp|Q9ULC5|ACSL5_HUMAN
Long-chain-fatty-acid--CoA ligase 5
Search

ACSL5

0.78	LOW QUALITY PROTEIN: long-chain-fatty-acid--CoA ligase 5

0.39	GO:0001676	long-chain fatty acid metabolic process
0.38	GO:2001236	regulation of extrinsic apoptotic signaling pathway
0.36	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport
0.36	GO:0007405	neuroblast proliferation
0.35	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.35	GO:0032000	positive regulation of fatty acid beta-oxidation
0.35	GO:0010867	positive regulation of triglyceride biosynthetic process
0.35	GO:0070723	response to cholesterol
0.35	GO:0009744	response to sucrose
0.35	GO:0009749	response to glucose

0.52	GO:0016874	ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005730	nucleolus
0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.37	GO:0031968	organelle outer membrane
0.36	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.52

GO:0016874

sp|Q9ULC6|PADI1_HUMAN
Protein-arginine deiminase type-1
Search

0.90	Peptidylarginine deiminase type III

0.81	GO:0018101	protein citrullination
0.54	GO:0016570	histone modification
0.49	GO:0019546	arginine deiminase pathway
0.48	GO:0006338	chromatin remodeling
0.46	GO:0019827	stem cell population maintenance
0.45	GO:0010848	regulation of chromatin disassembly
0.45	GO:1901624	negative regulation of lymphocyte chemotaxis
0.45	GO:0006334	nucleosome assembly
0.44	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.43	GO:0030520	intracellular estrogen receptor signaling pathway

0.80	GO:0004668	protein-arginine deiminase activity
0.69	GO:0005509	calcium ion binding
0.50	GO:0042802	identical protein binding
0.46	GO:0016990	arginine deiminase activity
0.45	GO:0034618	arginine binding
0.43	GO:0030331	estrogen receptor binding
0.42	GO:0046983	protein dimerization activity

0.49	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.39	GO:0043234	protein complex
0.39	GO:0070062	extracellular exosome
0.39	GO:0005694	chromosome
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.5.3.15

GO:0004668

sp|Q9ULC8|ZDHC8_HUMAN
Probable palmitoyltransferase ZDHHC8
Search

ZDHHC8

0.57	Palmitoyltransferase

0.85	GO:0018345	protein palmitoylation
0.57	GO:1903146	regulation of autophagy of mitochondrion
0.57	GO:1903955	positive regulation of protein targeting to mitochondrion
0.54	GO:0007626	locomotory behavior
0.37	GO:0034380	high-density lipoprotein particle assembly

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0005515	protein binding

0.52	GO:0005794	Golgi apparatus
0.44	GO:0005739	mitochondrion
0.40	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005829	cytosol
0.34	GO:0030425	dendrite
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:2.3.1.225

GO:0019706

sp|Q9ULD0|OGDHL_HUMAN
2-oxoglutarate dehydrogenase-like, mitochondrial
Search

OGDHL

0.97	Oxoglutarate dehydrogenase like

0.71	GO:0006099	tricarboxylic acid cycle
0.53	GO:0061034	olfactory bulb mitral cell layer development
0.52	GO:0018335	protein succinylation
0.52	GO:0021860	pyramidal neuron development
0.52	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb
0.51	GO:0021794	thalamus development
0.51	GO:0021756	striatum development
0.51	GO:0006104	succinyl-CoA metabolic process
0.50	GO:0021695	cerebellar cortex development
0.50	GO:0021766	hippocampus development

0.80	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity
0.73	GO:0030976	thiamine pyrophosphate binding
0.53	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity

0.59	GO:0045252	oxoglutarate dehydrogenase complex
0.49	GO:0005829	cytosol
0.48	GO:0005739	mitochondrion
0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80	EC:1.2.4.2	GO:0004591
0.53	KEGG:R08549	GO:0034602

sp|Q9ULD2|MTUS1_HUMAN
Microtubule-associated tumor suppressor 1
Search

MTUS1

0.88	Microtubule-associated tumor suppressor 1

0.42	GO:0007049	cell cycle
0.40	GO:0010758	regulation of macrophage chemotaxis
0.36	GO:0071375	cellular response to peptide hormone stimulus
0.35	GO:0006757	ATP generation from ADP
0.35	GO:0006090	pyruvate metabolic process
0.34	GO:0016052	carbohydrate catabolic process
0.34	GO:0019362	pyridine nucleotide metabolic process

0.36	GO:0004332	fructose-bisphosphate aldolase activity
0.32	GO:0019901	protein kinase binding

0.69	GO:0005730	nucleolus
0.67	GO:0015630	microtubule cytoskeleton
0.46	GO:0005794	Golgi apparatus
0.42	GO:0005739	mitochondrion
0.41	GO:0005615	extracellular space
0.40	GO:0005886	plasma membrane
0.40	GO:0099513	polymeric cytoskeletal fiber
0.32	GO:0030496	midbody
0.32	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.36

EC:4.1.2.13

GO:0004332

sp|Q9ULD4|BRPF3_HUMAN
Bromodomain and PHD finger-containing protein 3
Search

BRPF3

0.93	Bromodomain and PHD finger-containing protein 3

0.60	GO:0043966	histone H3 acetylation
0.37	GO:0002576	platelet degranulation

0.53	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.61	GO:0070776	MOZ/MORF histone acetyltransferase complex
0.35	GO:0005829	cytosol
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q9ULD5|ZN777_HUMAN
Zinc finger protein 777
Search

0.50	LOW QUALITY PROTEIN: zinc finger protein 777

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:1901216	positive regulation of neuron death
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0042802	identical protein binding

0.45	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q9ULD6|INTU_HUMAN
Protein inturned
Search

INTU

0.96	Inturned planar cell polarity effector homolog

0.85	GO:0010839	negative regulation of keratinocyte proliferation
0.84	GO:0021513	spinal cord dorsal/ventral patterning
0.84	GO:0045880	positive regulation of smoothened signaling pathway
0.83	GO:0044458	motile cilium assembly
0.82	GO:0042733	embryonic digit morphogenesis
0.82	GO:0030216	keratinocyte differentiation
0.81	GO:1905515	non-motile cilium assembly
0.80	GO:0031069	hair follicle morphogenesis
0.80	GO:0021915	neural tube development
0.79	GO:0030278	regulation of ossification

0.37

GO:0005515

protein binding

0.81	GO:0036064	ciliary basal body
0.78	GO:0031514	motile cilium
0.51	GO:0009986	cell surface
0.48	GO:0005737	cytoplasm
0.38	GO:0045177	apical part of cell
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9ULD8|KCNH3_HUMAN
Potassium voltage-gated channel subfamily H member 3
Search

KCNH3

0.94	Potassium voltage-gated channel subfamily H member 3

0.76	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.65	GO:0023014	signal transduction by protein phosphorylation
0.62	GO:0000160	phosphorelay signal transduction system
0.50	GO:0042391	regulation of membrane potential
0.33	GO:0007631	feeding behavior
0.33	GO:0007218	neuropeptide signaling pathway

0.77	GO:0005249	voltage-gated potassium channel activity
0.66	GO:0000155	phosphorelay sensor kinase activity
0.37	GO:0043855	cyclic nucleotide-gated ion channel activity
0.36	GO:0005515	protein binding
0.33	GO:0030551	cyclic nucleotide binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005887	integral component of plasma membrane
0.45	GO:0005622	intracellular
0.35	GO:0034705	potassium channel complex

0.66

EC:2.7.3

GO:0000155

sp|Q9ULD9|ZN608_HUMAN
Zinc finger protein 608
Search

ZNF608

0.97	Zinc finger protein 608

0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:2000291	regulation of myoblast proliferation
0.39	GO:2001224	positive regulation of neuron migration
0.37	GO:0033085	negative regulation of T cell differentiation in thymus
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding

0.38

GO:0032039

integrator complex

sp|Q9ULE0|WWC3_HUMAN
Protein WWC3
Search

WWC3

0.97	WWC family member 3

0.86	GO:0035331	negative regulation of hippo signaling
0.85	GO:0046621	negative regulation of organ growth
0.77	GO:0000122	negative regulation of transcription by RNA polymerase II

0.81	GO:0032947	protein complex scaffold activity
0.77	GO:0019900	kinase binding

0.68

GO:0005829

cytosol

sp|Q9ULE3|DEN2A_HUMAN
DENN domain-containing protein 2A
Search

DENND2A

0.96	LOW QUALITY PROTEIN: DENN domain-containing protein 2A

0.79	GO:0042147	retrograde transport, endosome to Golgi
0.65	GO:0065009	regulation of molecular function
0.40	GO:0015031	protein transport
0.35	GO:0006468	protein phosphorylation
0.35	GO:0035556	intracellular signal transduction

0.83	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0046872	metal ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0015629	actin cytoskeleton
0.67	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.36

GO:0004674

sp|Q9ULE4|F184B_HUMAN
Protein FAM184B
Search

0.47	GO:0005515	protein binding
0.35	GO:0016787	hydrolase activity

0.46

GO:0005615

extracellular space

0.35

GO:0016787

sp|Q9ULE6|PALD_HUMAN
Paladin
Search

PALD1

0.97	Phosphatase domain containing, paladin 1

0.57	GO:0016311	dephosphorylation
0.47	GO:0036211	protein modification process
0.44	GO:0044267	cellular protein metabolic process
0.36	GO:0007050	cell cycle arrest
0.35	GO:0006508	proteolysis
0.35	GO:1903047	mitotic cell cycle process
0.34	GO:0044843	cell cycle G1/S phase transition
0.34	GO:0051255	spindle midzone assembly
0.34	GO:0051231	spindle elongation
0.34	GO:0007096	regulation of exit from mitosis

0.57	GO:0016791	phosphatase activity
0.46	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0005515	protein binding
0.32	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.31	GO:0046872	metal ion binding

0.63	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.34	GO:0072686	mitotic spindle
0.34	GO:0000922	spindle pole
0.33	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

0.57

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q9ULF5|S39AA_HUMAN
Zinc transporter ZIP10
Search

SLC39A10

0.91	Zinc transporter ZIP10 isoform A

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.46	GO:1903615	positive regulation of protein tyrosine phosphatase activity
0.45	GO:0002903	negative regulation of B cell apoptotic process
0.45	GO:0050861	positive regulation of B cell receptor signaling pathway
0.44	GO:0006882	cellular zinc ion homeostasis
0.44	GO:0030890	positive regulation of B cell proliferation
0.41	GO:0072511	divalent inorganic cation transport
0.35	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.35	GO:0010043	response to zinc ion

0.69	GO:0046873	metal ion transmembrane transporter activity
0.42	GO:0072509	divalent inorganic cation transmembrane transporter activity

0.39

GO:0005887

integral component of plasma membrane

sp|Q9ULG1|INO80_HUMAN
DNA helicase INO80
Search

INO80

0.92	INO80 complex subunit

0.78	GO:0006338	chromatin remodeling
0.65	GO:0006281	DNA repair
0.64	GO:0010571	positive regulation of nuclear cell cycle DNA replication
0.62	GO:0071479	cellular response to ionizing radiation
0.61	GO:0034644	cellular response to UV
0.61	GO:0030307	positive regulation of cell growth
0.61	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.60	GO:0051225	spindle assembly
0.58	GO:0000070	mitotic sister chromatid segregation
0.58	GO:0097659	nucleic acid-templated transcription

0.63	GO:0043014	alpha-tubulin binding
0.61	GO:0016887	ATPase activity
0.60	GO:0004386	helicase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0140097	catalytic activity, acting on DNA
0.37	GO:0003779	actin binding

0.80	GO:0031011	Ino80 complex
0.58	GO:0045111	intermediate filament cytoskeleton
0.58	GO:0016604	nuclear body
0.45	GO:0005886	plasma membrane
0.36	GO:0005874	microtubule
0.33	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

sp|Q9ULG3|K1257_HUMAN
Uncharacterized protein KIAA1257
Search

sp|Q9ULG6|CCPG1_HUMAN
Cell cycle progression protein 1
Search

CCPG1

0.96	Cell cycle progression protein 1

0.86	GO:1904475	regulation of Ras GTPase binding
0.86	GO:1905097	regulation of guanyl-nucleotide exchange factor activity
0.57	GO:0045787	positive regulation of cell cycle
0.57	GO:0008284	positive regulation of cell proliferation
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0007049	cell cycle
0.37	GO:0003341	cilium movement

0.35

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q9ULH0|KDIS_HUMAN
Kinase D-interacting substrate of 220 kDa
Search

KIDINS220

0.88	Kinase D-interacting substrate

0.58	GO:0048813	dendrite morphogenesis
0.53	GO:0001701	in utero embryonic development
0.50	GO:0016310	phosphorylation
0.49	GO:0038180	nerve growth factor signaling pathway
0.44	GO:0045859	regulation of protein kinase activity
0.38	GO:0010976	positive regulation of neuron projection development
0.36	GO:0043410	positive regulation of MAPK cascade
0.36	GO:0033674	positive regulation of kinase activity

0.52	GO:0016301	kinase activity
0.47	GO:0030165	PDZ domain binding
0.45	GO:0019887	protein kinase regulator activity
0.35	GO:0019901	protein kinase binding

0.38	GO:0005770	late endosome
0.36	GO:0005829	cytosol
0.35	GO:0043234	protein complex
0.32	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

sp|Q9ULH1|ASAP1_HUMAN
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Search

ASAP1

0.93	LOW QUALITY PROTEIN: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

0.75	GO:0043547	positive regulation of GTPase activity
0.57	GO:1903527	positive regulation of membrane tubulation
0.56	GO:0061000	negative regulation of dendritic spine development
0.55	GO:0071803	positive regulation of podosome assembly
0.51	GO:0060271	cilium assembly

0.76	GO:0005096	GTPase activator activity
0.54	GO:0001786	phosphatidylserine binding
0.54	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.52	GO:0046872	metal ion binding
0.52	GO:0045296	cadherin binding
0.35	GO:0032266	phosphatidylinositol-3-phosphate binding
0.34	GO:0017124	SH3 domain binding

0.54	GO:0002102	podosome
0.53	GO:0043197	dendritic spine
0.52	GO:0031253	cell projection membrane
0.36	GO:0005829	cytosol

sp|Q9ULH4|LRFN2_HUMAN
Leucine-rich repeat and fibronectin type-III domain-containing protein 2
Search

LRFN2

0.90	Leucine-rich repeat and fibronectin type-III domain-containing protein 2

0.51

GO:0007409

axonogenesis

0.35

GO:0005515

protein binding

0.56	GO:0009986	cell surface
0.50	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005615	extracellular space
0.41	GO:0045211	postsynaptic membrane
0.40	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q9ULH7|MKL2_HUMAN
MKL/myocardin-like protein 2
Search

MKL2

0.94	Megakaryoblastic leukemia (translocation) 1

0.81	GO:0045844	positive regulation of striated muscle tissue development
0.73	GO:0045944	positive regulation of transcription by RNA polymerase II
0.62	GO:0051145	smooth muscle cell differentiation
0.55	GO:0006366	transcription by RNA polymerase II
0.46	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.43	GO:0007517	muscle organ development
0.41	GO:0001764	neuron migration
0.40	GO:0030900	forebrain development
0.40	GO:0031175	neuron projection development
0.40	GO:0001889	liver development

0.77	GO:0003713	transcription coactivator activity
0.77	GO:0045296	cadherin binding
0.61	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.57	GO:0001104	RNA polymerase II transcription cofactor activity
0.48	GO:0003779	actin binding
0.46	GO:0004864	protein phosphatase inhibitor activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0000976	transcription regulatory region sequence-specific DNA binding

0.49	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|Q9ULI0|ATD2B_HUMAN
ATPase family AAA domain-containing protein 2B
Search

ATAD2B

0.92	ATPase family AAA domain-containing protein 2

0.50	GO:0031936	negative regulation of chromatin silencing
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0006325	chromatin organization

0.58	GO:0070577	lysine-acetylated histone binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0003682	chromatin binding
0.42	GO:0016887	ATPase activity

0.50	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0016887

sp|Q9ULI1|NWD2_HUMAN
NACHT and WD repeat domain-containing protein 2
Search

NWD2

0.94	Leucine-rich repeat and WD repeat-containing protein KIAA1239

0.30

GO:0003824

catalytic activity

0.30

GO:0044425

membrane part

sp|Q9ULI2|RIMKB_HUMAN
Beta-citrylglutamate synthase B
Search

RIMKLB

0.96	N-acetylaspartylglutamate synthase A

0.60	GO:0006464	cellular protein modification process
0.36	GO:0008652	cellular amino acid biosynthetic process

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.51	GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity
0.50	GO:0072591	citrate-L-glutamate ligase activity

0.37

GO:0005829

cytosol

sp|Q9ULI3|HEG1_HUMAN
Protein HEG homolog 1
Search

HEG1

0.94	Heart development protein with EGF like domains 1

0.84	GO:0007043	cell-cell junction assembly
0.82	GO:0003017	lymph circulation
0.81	GO:0090271	positive regulation of fibroblast growth factor production
0.80	GO:0007507	heart development
0.78	GO:0048845	venous blood vessel morphogenesis
0.78	GO:0001886	endothelial cell morphogenesis
0.75	GO:0061384	heart trabecula morphogenesis
0.75	GO:0001945	lymph vessel development
0.74	GO:0060415	muscle tissue morphogenesis
0.74	GO:0001570	vasculogenesis

0.70

GO:0005509

calcium ion binding

0.70	GO:0009897	external side of plasma membrane
0.66	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|Q9ULI4|KI26A_HUMAN
Kinesin-like protein KIF26A
Search

KIF26A

0.88	Kinesin family member 26Aa

0.73	GO:0007018	microtubule-based movement
0.64	GO:0001560	regulation of cell growth by extracellular stimulus
0.61	GO:0048484	enteric nervous system development
0.53	GO:0009968	negative regulation of signal transduction
0.51	GO:0072092	ureteric bud invasion
0.47	GO:0030010	establishment of cell polarity
0.45	GO:0022409	positive regulation of cell-cell adhesion

0.73	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0016887	ATPase activity

0.52

GO:0005871

kinesin complex

0.43

GO:0016887

sp|Q9ULJ1|ODF2L_HUMAN
Outer dense fiber protein 2-like
Search

ODF2L

0.74	Outer dense fiber of sperm tails 2 like

0.76	GO:0005813	centrosome
0.30	GO:0044425	membrane part

sp|Q9ULJ3|ZBT21_HUMAN
Zinc finger and BTB domain-containing protein 21
Search

ZBTB21

0.62	Zinc finger and BTB domain-containing protein 21

0.39	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0006351	transcription, DNA-templated

0.58	GO:0008327	methyl-CpG binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

sp|Q9ULJ6|ZMIZ1_HUMAN
Zinc finger MIZ domain-containing protein 1
Search

ZMIZ1

0.93	Zinc finger MIZ domain-containing protein 1

0.58	GO:0007296	vitellogenesis
0.56	GO:0048146	positive regulation of fibroblast proliferation
0.56	GO:0048844	artery morphogenesis
0.55	GO:0045582	positive regulation of T cell differentiation
0.55	GO:0001570	vasculogenesis
0.55	GO:0045747	positive regulation of Notch signaling pathway
0.54	GO:0007569	cell aging
0.54	GO:0003007	heart morphogenesis
0.53	GO:0048589	developmental growth
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II

0.63	GO:0008270	zinc ion binding
0.36	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.33	GO:0005515	protein binding

0.50	GO:0005654	nucleoplasm
0.36	GO:0043596	nuclear replication fork
0.34	GO:0005739	mitochondrion

sp|Q9ULJ7|ANR50_HUMAN
Ankyrin repeat domain-containing protein 50
Search

ANKRD50

0.82	Ankyrin repeat domain-containing protein 50

0.86	GO:1990126	retrograde transport, endosome to plasma membrane
0.37	GO:0015031	protein transport

0.37

GO:0005515

protein binding

0.45	GO:0005622	intracellular
0.38	GO:0031982	vesicle
0.37	GO:0012505	endomembrane system

sp|Q9ULJ8|NEB1_HUMAN
Neurabin-1
Search

PPP1R9A

0.90	LOW QUALITY PROTEIN: neurabin-1

0.84	GO:0019722	calcium-mediated signaling
0.75	GO:0007015	actin filament organization
0.61	GO:0031175	neuron projection development
0.54	GO:1904049	negative regulation of spontaneous neurotransmitter secretion
0.53	GO:1900454	positive regulation of long term synaptic depression
0.52	GO:0051823	regulation of synapse structural plasticity
0.52	GO:1900272	negative regulation of long-term synaptic potentiation
0.51	GO:0051497	negative regulation of stress fiber assembly
0.51	GO:0060999	positive regulation of dendritic spine development
0.51	GO:0061001	regulation of dendritic spine morphogenesis

0.51	GO:0005515	protein binding
0.45	GO:0044877	macromolecular complex binding

0.85	GO:0043197	dendritic spine
0.85	GO:0030175	filopodium
0.81	GO:0030864	cortical actin cytoskeleton
0.65	GO:0030426	growth cone
0.50	GO:0031594	neuromuscular junction
0.49	GO:0014069	postsynaptic density
0.49	GO:0030027	lamellipodium
0.48	GO:0043025	neuronal cell body
0.44	GO:0005829	cytosol
0.43	GO:0030054	cell junction

sp|Q9ULK0|GRID1_HUMAN
Glutamate receptor ionotropic, delta-1
Search

GRID1

0.93	Glutamate ionotropic receptor delta type subunit 1

0.77	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.54	GO:0035176	social behavior

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.76	GO:0004970	ionotropic glutamate receptor activity
0.34	GO:0005515	protein binding

0.75	GO:0045211	postsynaptic membrane
0.71	GO:0030054	cell junction
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9ULK2|AT7L1_HUMAN
Ataxin-7-like protein 1
Search

ATXN7L1

0.92	Ataxin 7 like 1

sp|Q9ULK4|MED23_HUMAN
Mediator of RNA polymerase II transcription subunit 23
Search

MED23

0.90	Mediator of RNA polymerase II transcription subunit 23

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:2000409	positive regulation of T cell extravasation
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:0010604	positive regulation of macromolecule metabolic process
0.40	GO:0050768	negative regulation of neurogenesis
0.39	GO:0072358	cardiovascular system development
0.38	GO:0016567	protein ubiquitination

0.39	GO:0003713	transcription coactivator activity
0.39	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0005515	protein binding

0.74	GO:0005667	transcription factor complex
0.43	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

sp|Q9ULK5|VANG2_HUMAN
Vang-like protein 2
Search

VANGL2

0.94	VANGL planar cell polarity protein 2

0.70	GO:0007275	multicellular organism development
0.57	GO:0060028	convergent extension involved in axis elongation
0.57	GO:0036342	post-anal tail morphogenesis
0.57	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.56	GO:0001736	establishment of planar polarity
0.55	GO:0060601	lateral sprouting from an epithelium
0.55	GO:0060600	dichotomous subdivision of an epithelial terminal unit
0.54	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
0.54	GO:0030111	regulation of Wnt signaling pathway
0.54	GO:0045176	apical protein localization

0.35

GO:0005515

protein binding

0.57	GO:0016328	lateral plasma membrane
0.55	GO:0060187	cell pole
0.52	GO:0097517	contractile actin filament bundle
0.52	GO:0042641	actomyosin
0.51	GO:0016323	basolateral plasma membrane
0.51	GO:0016324	apical plasma membrane
0.50	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.49	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|Q9ULK6|RN150_HUMAN
RING finger protein 150
Search

RNF150

0.91	LOW QUALITY PROTEIN: RING finger protein 150

0.33	GO:0012501	programmed cell death
0.33	GO:0016567	protein ubiquitination

0.34	GO:0046872	metal ion binding
0.33	GO:0004842	ubiquitin-protein transferase activity

0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004842

sp|Q9ULL0|K1210_HUMAN
Uncharacterized protein KIAA1210
Search

0.13	Acrosomal protein KIAA1210

0.82	GO:0061832	basal ectoplasmic specialization
0.71	GO:0001669	acrosomal vesicle
0.30	GO:0044425	membrane part

sp|Q9ULL1|PKHG1_HUMAN
Pleckstrin homology domain-containing family G member 1
Search

PLEKHG1

0.95	Pleckstrin like proteiny domain-containing family G member 1

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.39	GO:0035556	intracellular signal transduction
0.31	GO:0055114	oxidation-reduction process

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.32	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity

0.54	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.32	EC:1.5.1.5	GO:0004488
0.32	KEGG:R01220	GO:0004488

sp|Q9ULL4|PLXB3_HUMAN
Plexin-B3
Search

PLXNB3

0.88	Putative plexins functional semaphorin receptor (Fragment)

0.83	GO:0071526	semaphorin-plexin signaling pathway
0.61	GO:0034260	negative regulation of GTPase activity
0.60	GO:0050918	positive chemotaxis
0.60	GO:0001938	positive regulation of endothelial cell proliferation
0.60	GO:0010976	positive regulation of neuron projection development
0.59	GO:0007162	negative regulation of cell adhesion
0.58	GO:0030336	negative regulation of cell migration
0.58	GO:0060326	cell chemotaxis
0.56	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.55	GO:0048675	axon extension

0.84	GO:0017154	semaphorin receptor activity
0.64	GO:0051022	Rho GDP-dissociation inhibitor binding
0.62	GO:0098632	cell-cell adhesion mediator activity
0.55	GO:0019904	protein domain specific binding
0.38	GO:0004672	protein kinase activity
0.37	GO:0005324	long-chain fatty acid transporter activity
0.36	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0009986	cell surface
0.36	GO:0005886	plasma membrane
0.36	GO:0042579	microbody
0.36	GO:0002116	semaphorin receptor complex
0.30	GO:0016021	integral component of membrane

sp|Q9ULL5|PRR12_HUMAN
Proline-rich protein 12
Search

PRR12

0.84	Proline-rich protein 12

0.33

GO:0030163

protein catabolic process

0.53	GO:0005509	calcium ion binding
0.43	GO:0003677	DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016787	hydrolase activity

0.70	GO:0014069	postsynaptic density
0.67	GO:0045211	postsynaptic membrane
0.65	GO:0043005	neuron projection
0.63	GO:0030054	cell junction
0.53	GO:0005634	nucleus
0.51	GO:0005576	extracellular region
0.37	GO:0005581	collagen trimer
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|Q9ULL8|SHRM4_HUMAN
Protein Shroom4
Search

SHROOM4

0.94	Shroom family member 4

0.69	GO:0050890	cognition
0.67	GO:0007420	brain development
0.62	GO:0007015	actin filament organization
0.47	GO:0045176	apical protein localization
0.46	GO:0032401	establishment of melanosome localization
0.39	GO:0000902	cell morphogenesis

0.78

GO:0051015

actin filament binding

0.72	GO:0031941	filamentous actin
0.72	GO:0009925	basal plasma membrane
0.72	GO:0016460	myosin II complex
0.70	GO:0097517	contractile actin filament bundle
0.70	GO:0042641	actomyosin
0.67	GO:0016324	apical plasma membrane
0.67	GO:0030864	cortical actin cytoskeleton
0.64	GO:0009898	cytoplasmic side of plasma membrane

sp|Q9ULM0|PKHH1_HUMAN
Pleckstrin homology domain-containing family H member 1
Search

PLEKHH1

0.95	Pleckstrin domain-containing family H member 2

0.69

GO:0005856

cytoskeleton

sp|Q9ULM2|ZN490_HUMAN
Zinc finger protein 490
Search

0.70	Zinc finger protein 69

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.41	GO:0006351	transcription, DNA-templated
0.39	GO:0014022	neural plate elongation
0.39	GO:0060029	convergent extension involved in organogenesis
0.38	GO:0060028	convergent extension involved in axis elongation
0.38	GO:0060669	embryonic placenta morphogenesis
0.38	GO:0060027	convergent extension involved in gastrulation
0.36	GO:1902679	negative regulation of RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.39	GO:0001222	transcription corepressor binding
0.38	GO:0003700	DNA binding transcription factor activity

0.44

GO:0005634

nucleus

sp|Q9ULM3|YETS2_HUMAN
YEATS domain-containing protein 2
Search

YEATS2

0.97	YEATS domain-containing protein 2

0.61	GO:0043966	histone H3 acetylation
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II

0.59	GO:0017025	TBP-class protein binding
0.59	GO:0140030	modification-dependent protein binding
0.58	GO:0042393	histone binding

0.61	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.59	GO:0072686	mitotic spindle

sp|Q9ULM6|CNOT6_HUMAN
CCR4-NOT transcription complex subunit 6
Search

CNOT6

0.92	CCR4-NOT transcription complex subunit 6

0.74	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.60	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.60	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity
0.57	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.56	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic
0.56	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay
0.55	GO:0008284	positive regulation of cell proliferation
0.45	GO:0061157	mRNA destabilization
0.39	GO:0031047	gene silencing by RNA
0.37	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

0.83	GO:0004535	poly(A)-specific ribonuclease activity
0.35	GO:0003723	RNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.57	GO:0030014	CCR4-NOT complex
0.41	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.83

EC:3.1.13.4

GO:0004535

sp|Q9ULN7|PNML2_HUMAN
PNMA-like protein 2
Search

0.86	Paraneoplastic antigen-like protein 8B

0.40

GO:0043065

positive regulation of apoptotic process

0.57	GO:0008270	zinc ion binding
0.47	GO:0003676	nucleic acid binding

0.39

GO:0005730

nucleolus

sp|Q9ULP0|NDRG4_HUMAN
Protein NDRG4
Search

NDRG4

0.97	NDRG family member 4

0.80	GO:2001135	regulation of endocytic recycling
0.80	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.79	GO:0014912	negative regulation of smooth muscle cell migration
0.79	GO:0060973	cell migration involved in heart development
0.77	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.77	GO:0048662	negative regulation of smooth muscle cell proliferation
0.77	GO:0008542	visual learning
0.71	GO:0048278	vesicle docking
0.61	GO:0007399	nervous system development
0.59	GO:0060038	cardiac muscle cell proliferation

0.73	GO:0016323	basolateral plasma membrane
0.73	GO:0031253	cell projection membrane
0.47	GO:0005737	cytoplasm

sp|Q9ULP9|TBC24_HUMAN
TBC1 domain family member 24
Search

TBC1D24

0.91	TBC1 domain family member 24 isoform B

0.71	GO:0031175	neuron projection development
0.59	GO:0043547	positive regulation of GTPase activity
0.57	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.55	GO:1903204	negative regulation of oxidative stress-induced neuron death
0.54	GO:1902017	regulation of cilium assembly
0.48	GO:2001224	positive regulation of neuron migration
0.48	GO:2000463	positive regulation of excitatory postsynaptic potential
0.48	GO:0050775	positive regulation of dendrite morphogenesis

0.59	GO:0005096	GTPase activator activity
0.40	GO:0005515	protein binding

0.66	GO:0030054	cell junction
0.54	GO:0043195	terminal bouton
0.54	GO:0031594	neuromuscular junction
0.51	GO:0005886	plasma membrane
0.46	GO:0005737	cytoplasm

sp|Q9ULQ0|STRP2_HUMAN
Striatin-interacting protein 2
Search

STRIP2

0.72	Striatin-interacting protein 1 homolog

sp|Q9ULQ1|TPC1_HUMAN
Two pore calcium channel protein 1
Search

TPCN1

0.94	Two pore calcium channel protein 1

0.77	GO:0070588	calcium ion transmembrane transport
0.56	GO:0051283	negative regulation of sequestering of calcium ion
0.55	GO:0060402	calcium ion transport into cytosol
0.52	GO:0010508	positive regulation of autophagy
0.48	GO:0086010	membrane depolarization during action potential
0.37	GO:0034765	regulation of ion transmembrane transport
0.32	GO:0030317	flagellated sperm motility

0.82	GO:0005245	voltage-gated calcium channel activity
0.58	GO:0072345	NAADP-sensitive calcium-release channel activity
0.50	GO:0042802	identical protein binding
0.32	GO:0005227	calcium activated cation channel activity

0.53	GO:0005765	lysosomal membrane
0.51	GO:0010008	endosome membrane
0.38	GO:0005886	plasma membrane
0.32	GO:0034704	calcium channel complex

sp|Q9ULR0|ISY1_HUMAN
Pre-mRNA-splicing factor ISY1 homolog
Search

0.78	Pre-mRNA-splicing factor ISY1

0.85	GO:0000350	generation of catalytic spliceosome for second transesterification step
0.50	GO:0000389	mRNA 3'-splice site recognition
0.35	GO:0006283	transcription-coupled nucleotide-excision repair

0.50	GO:0000384	first spliceosomal transesterification activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.31	GO:0008270	zinc ion binding

0.50	GO:0071020	post-spliceosomal complex
0.49	GO:0000974	Prp19 complex
0.49	GO:0071012	catalytic step 1 spliceosome
0.47	GO:0071014	post-mRNA release spliceosomal complex
0.47	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0005654	nucleoplasm

sp|Q9ULR3|PPM1H_HUMAN
Protein phosphatase 1H
Search

0.11	Putative serine/threonine phosphatase

0.72

GO:0006470

protein dephosphorylation

0.77

GO:0004722

protein serine/threonine phosphatase activity

0.49	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q9ULR5|PAI2B_HUMAN
Polyadenylate-binding protein-interacting protein 2B
Search

PAIP2B

0.97	Polyadenylate-binding protein-interacting protein 2B

0.80	GO:0045947	negative regulation of translational initiation
0.66	GO:1900271	regulation of long-term synaptic potentiation
0.63	GO:0007613	memory
0.60	GO:0007283	spermatogenesis
0.35	GO:0007018	microtubule-based movement

0.85	GO:0030371	translation repressor activity
0.75	GO:0090079	translation regulator activity, nucleic acid binding
0.58	GO:0003729	mRNA binding
0.41	GO:0008143	poly(A) binding
0.38	GO:0005515	protein binding
0.35	GO:0003777	microtubule motor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005737	cytoplasm
0.36	GO:0016459	myosin complex

sp|Q9ULS5|TMCC3_HUMAN
Transmembrane and coiled-coil domains protein 3
Search

TMCC3

0.97	Transmembrane and coiled-coil domains protein 3

0.34	GO:0006955	immune response
0.33	GO:0022900	electron transport chain

0.33	GO:0005515	protein binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0003723	RNA binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008144	drug binding
0.32	GO:0016740	transferase activity

0.30

GO:0031224

intrinsic component of membrane

0.33

EC:1.6.5.3

GO:0008137

sp|Q9ULS6|KCNS2_HUMAN
Potassium voltage-gated channel subfamily S member 2
Search

KCNS2

0.97	Potassium voltage-gated channel modifier subfamily S member 2

0.78	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.56	GO:0043266	regulation of potassium ion transport
0.55	GO:0022898	regulation of transmembrane transporter activity
0.41	GO:0050794	regulation of cellular process
0.33	GO:0002791	regulation of peptide secretion
0.33	GO:0051223	regulation of protein transport
0.33	GO:0010817	regulation of hormone levels
0.33	GO:0023051	regulation of signaling

0.78	GO:0005249	voltage-gated potassium channel activity
0.40	GO:0015459	potassium channel regulator activity
0.33	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.54	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005794	Golgi apparatus
0.39	GO:0005829	cytosol

sp|Q9ULT0|TTC7A_HUMAN
Tetratricopeptide repeat protein 7A
Search

TTC7A

0.85	Tetratricopeptide repeat domain 7

0.83	GO:0072659	protein localization to plasma membrane
0.72	GO:0030097	hemopoiesis
0.69	GO:0006879	cellular iron ion homeostasis
0.53	GO:0046854	phosphatidylinositol phosphorylation

0.34

GO:0005515

protein binding

0.50	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9ULT6|ZNRF3_HUMAN
E3 ubiquitin-protein ligase ZNRF3
Search

ZNRF3

0.92	E3 ubiquitin-protein ligase ZNRF3

0.51	GO:0038018	Wnt receptor catabolic process
0.50	GO:2000051	negative regulation of non-canonical Wnt signaling pathway
0.48	GO:0072089	stem cell proliferation
0.48	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.46	GO:0016055	Wnt signaling pathway
0.45	GO:0090175	regulation of establishment of planar polarity
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0016567	protein ubiquitination

0.60	GO:0016874	ligase activity
0.45	GO:0005109	frizzled binding
0.44	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0061659	ubiquitin-like protein ligase activity
0.38	GO:0046872	metal ion binding

0.42

GO:0005887

integral component of plasma membrane

0.60	EC:6	GO:0016874
0.44	KEGG:R03876	GO:0004842

sp|Q9ULT8|HECD1_HUMAN
E3 ubiquitin-protein ligase HECTD1
Search

HECTD1

0.50	HECT domain containing 1

0.73	GO:0016567	protein ubiquitination
0.41	GO:0060708	spongiotrophoblast differentiation
0.41	GO:0001779	natural killer cell differentiation
0.41	GO:0060707	trophoblast giant cell differentiation
0.40	GO:1903077	negative regulation of protein localization to plasma membrane
0.40	GO:0003170	heart valve development
0.40	GO:0035904	aorta development
0.40	GO:0003281	ventricular septum development
0.40	GO:0001843	neural tube closure

0.73	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0046872	metal ion binding
0.49	GO:0061659	ubiquitin-like protein ligase activity
0.49	GO:0016874	ligase activity
0.36	GO:0005515	protein binding

0.38

GO:0005737

cytoplasm

0.49	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q9ULU4|PKCB1_HUMAN
Protein kinase C-binding protein 1
Search

ZMYND8

0.79	Zinc finger and MYND domain containing protein 8

0.77	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification
0.68	GO:0030336	negative regulation of cell migration
0.66	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:1902952	positive regulation of dendritic spine maintenance
0.42	GO:1902897	regulation of postsynaptic density protein 95 clustering
0.41	GO:0060999	positive regulation of dendritic spine development
0.41	GO:0098815	modulation of excitatory postsynaptic potential
0.41	GO:0051491	positive regulation of filopodium assembly
0.38	GO:0007399	nervous system development

0.70	GO:0070577	lysine-acetylated histone binding
0.70	GO:0140034	methylation-dependent protein binding
0.54	GO:0046872	metal ion binding
0.48	GO:0003712	transcription cofactor activity
0.47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.47	GO:0003682	chromatin binding
0.41	GO:0047485	protein N-terminus binding
0.40	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.40	GO:0070491	repressing transcription factor binding

0.54	GO:0005634	nucleus
0.41	GO:0043198	dendritic shaft
0.41	GO:0043197	dendritic spine
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9ULU8|CAPS1_HUMAN
Calcium-dependent secretion activator 1
Search

CADPS

0.86	Calcium dependent secretion activator

0.85	GO:1990504	dense core granule exocytosis
0.83	GO:0016079	synaptic vesicle exocytosis
0.56	GO:0050432	catecholamine secretion
0.50	GO:0140029	exocytic process
0.50	GO:0016050	vesicle organization
0.46	GO:0043623	cellular protein complex assembly
0.36	GO:0015031	protein transport

0.49	GO:0019901	protein kinase binding
0.37	GO:0008289	lipid binding
0.34	GO:0046872	metal ion binding

0.79	GO:0098793	presynapse
0.47	GO:0031410	cytoplasmic vesicle
0.37	GO:0012506	vesicle membrane
0.37	GO:0030054	cell junction
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol

sp|Q9ULV0|MYO5B_HUMAN
Unconventional myosin-Vb
Search

0.83	Unconventional myosin-Vb

0.73	GO:0007018	microtubule-based movement
0.45	GO:0098856	intestinal lipid absorption
0.44	GO:0043588	skin development
0.44	GO:0051648	vesicle localization
0.43	GO:0048546	digestive tract morphogenesis
0.43	GO:0007399	nervous system development
0.43	GO:0008361	regulation of cell size
0.42	GO:0030154	cell differentiation
0.42	GO:0099089	establishment of endoplasmic reticulum localization to postsynapse
0.42	GO:0099515	actin filament-based transport

0.75	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0017137	Rab GTPase binding
0.42	GO:0000146	microfilament motor activity
0.40	GO:0005516	calmodulin binding

0.76	GO:0016459	myosin complex
0.42	GO:0055037	recycling endosome
0.41	GO:0032433	filopodium tip
0.41	GO:0045179	apical cortex
0.41	GO:0042470	melanosome
0.41	GO:0032593	insulin-responsive compartment
0.40	GO:0001726	ruffle
0.40	GO:0005884	actin filament
0.40	GO:0035371	microtubule plus-end
0.40	GO:0005770	late endosome

0.34

GO:0016746

sp|Q9ULV1|FZD4_HUMAN
Frizzled-4
Search

FZD4

0.80	Frizzled class receptor 4

0.76	GO:0016055	Wnt signaling pathway
0.67	GO:0007275	multicellular organism development
0.61	GO:0035929	steroid hormone secretion
0.60	GO:0035426	extracellular matrix-cell signaling
0.60	GO:0031987	locomotion involved in locomotory behavior
0.58	GO:0010812	negative regulation of cell-substrate adhesion
0.58	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.58	GO:0034446	substrate adhesion-dependent cell spreading
0.57	GO:0043507	positive regulation of JUN kinase activity
0.57	GO:0022602	ovulation cycle process

0.84	GO:0042813	Wnt-activated receptor activity
0.59	GO:0017147	Wnt-protein binding
0.58	GO:0001540	amyloid-beta binding
0.58	GO:0030165	PDZ domain binding
0.57	GO:0019955	cytokine binding
0.55	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.44	GO:0004930	G-protein coupled receptor activity

0.60	GO:0106003	amyloid-beta complex
0.54	GO:0030425	dendrite
0.53	GO:0009986	cell surface
0.53	GO:0005911	cell-cell junction
0.43	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.35	GO:0030669	clathrin-coated endocytic vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|Q9ULV3|CIZ1_HUMAN
Cip1-interacting zinc finger protein
Search

CIZ1

0.96	Cip1-interacting zinc finger protein isoform 4

0.59	GO:0032298	positive regulation of DNA-dependent DNA replication initiation
0.57	GO:0051457	maintenance of protein location in nucleus

0.62	GO:0008270	zinc ion binding
0.55	GO:0030332	cyclin binding
0.50	GO:0003676	nucleic acid binding

0.59	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.44	GO:0005886	plasma membrane

sp|Q9ULV4|COR1C_HUMAN
Coronin-1C
Search

CORO1C

0.66

Coronin

0.74	GO:0030036	actin cytoskeleton organization
0.57	GO:2000394	positive regulation of lamellipodium morphogenesis
0.57	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.56	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.56	GO:0051895	negative regulation of focal adhesion assembly
0.56	GO:0010762	regulation of fibroblast migration
0.56	GO:1900027	regulation of ruffle assembly
0.55	GO:0001755	neural crest cell migration
0.55	GO:0010633	negative regulation of epithelial cell migration
0.54	GO:0090630	activation of GTPase activity

0.78	GO:0051015	actin filament binding
0.55	GO:0048365	Rac GTPase binding

0.74	GO:0015629	actin cytoskeleton
0.56	GO:0016600	flotillin complex
0.55	GO:0016328	lateral plasma membrane
0.53	GO:0030027	lamellipodium
0.49	GO:0031982	vesicle
0.36	GO:0005925	focal adhesion
0.32	GO:0005737	cytoplasm

sp|Q9ULV5|HSF4_HUMAN
Heat shock factor protein 4
Search

HSF4

0.94	Heat shock transcription factor 4

0.62	GO:0070207	protein homotrimerization
0.61	GO:0033169	histone H3-K9 demethylation
0.58	GO:0043010	camera-type eye development
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0045597	positive regulation of cell differentiation
0.55	GO:0007601	visual perception
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0048468	cell development
0.39	GO:0006366	transcription by RNA polymerase II

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.41	GO:0044212	transcription regulatory region DNA binding
0.41	GO:0019903	protein phosphatase binding
0.40	GO:0003690	double-stranded DNA binding
0.38	GO:0061770	translation elongation factor binding
0.38	GO:0042802	identical protein binding
0.37	GO:0046983	protein dimerization activity
0.37	GO:0051879	Hsp90 protein binding
0.37	GO:1990841	promoter-specific chromatin binding

0.60	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.46	GO:0044446	intracellular organelle part
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0035770	ribonucleoprotein granule
0.35	GO:0005694	chromosome
0.35	GO:0015630	microtubule cytoskeleton
0.35	GO:0005829	cytosol
0.34	GO:0043234	protein complex

sp|Q9ULV8|CBLC_HUMAN
E3 ubiquitin-protein ligase CBL-C
Search

CBLC

0.88	Signal transduction protein CBL-C

0.72	GO:0016567	protein ubiquitination
0.71	GO:0007166	cell surface receptor signaling pathway
0.69	GO:0023051	regulation of signaling
0.59	GO:0061099	negative regulation of protein tyrosine kinase activity
0.53	GO:0010648	negative regulation of cell communication
0.52	GO:0048585	negative regulation of response to stimulus
0.50	GO:0006511	ubiquitin-dependent protein catabolic process
0.50	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.46	GO:0048260	positive regulation of receptor-mediated endocytosis
0.43	GO:0043066	negative regulation of apoptotic process

0.85	GO:0001784	phosphotyrosine residue binding
0.73	GO:0004842	ubiquitin-protein transferase activity
0.70	GO:0005509	calcium ion binding
0.64	GO:0004871	signal transducer activity
0.56	GO:0017124	SH3 domain binding
0.53	GO:0005154	epidermal growth factor receptor binding
0.52	GO:0061659	ubiquitin-like protein ligase activity
0.51	GO:0030971	receptor tyrosine kinase binding
0.48	GO:0016874	ligase activity
0.46	GO:0046875	ephrin receptor binding

0.61	GO:0005634	nucleus
0.51	GO:0098857	membrane microdomain
0.42	GO:0098590	plasma membrane region
0.41	GO:0005829	cytosol
0.40	GO:0098797	plasma membrane protein complex
0.37	GO:0070062	extracellular exosome
0.36	GO:0005938	cell cortex
0.34	GO:0000151	ubiquitin ligase complex
0.34	GO:0030426	growth cone
0.34	GO:0005925	focal adhesion

0.48	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q9ULW0|TPX2_HUMAN
Targeting protein for Xklp2
Search

TPX2

0.95	Restricted expression proliferation-associated protein 100

0.84	GO:0060236	regulation of mitotic spindle organization
0.80	GO:0032147	activation of protein kinase activity
0.56	GO:0090307	mitotic spindle assembly
0.39	GO:0006915	apoptotic process
0.38	GO:0051301	cell division
0.37	GO:1901796	regulation of signal transduction by p53 class mediator
0.36	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.36	GO:0008283	cell proliferation
0.35	GO:0006468	protein phosphorylation
0.32	GO:0005975	carbohydrate metabolic process

0.59	GO:0061676	importin-alpha family protein binding
0.53	GO:0019901	protein kinase binding
0.35	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.32	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.77	GO:0005819	spindle
0.73	GO:0005874	microtubule
0.58	GO:0043203	axon hillock
0.56	GO:0045171	intercellular bridge
0.51	GO:0005815	microtubule organizing center
0.49	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol

0.32

EC:1.1.1

GO:0016616

sp|Q9ULW2|FZD10_HUMAN
Frizzled-10
Search

FZD10

0.96	Frizzled class receptor 10

0.76	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.54	GO:0034260	negative regulation of GTPase activity
0.54	GO:0043507	positive regulation of JUN kinase activity
0.50	GO:0032956	regulation of actin cytoskeleton organization
0.49	GO:0043547	positive regulation of GTPase activity
0.48	GO:1904394	negative regulation of skeletal muscle acetylcholine-gated channel clustering
0.47	GO:1990523	bone regeneration
0.46	GO:0071157	negative regulation of cell cycle arrest
0.46	GO:2000179	positive regulation of neural precursor cell proliferation

0.80	GO:0042813	Wnt-activated receptor activity
0.58	GO:0017147	Wnt-protein binding
0.46	GO:0004930	G-protein coupled receptor activity
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity
0.32	GO:0046872	metal ion binding

0.53	GO:0009986	cell surface
0.47	GO:0005654	nucleoplasm
0.46	GO:0031527	filopodium membrane
0.43	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005794	Golgi apparatus
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0031966	mitochondrial membrane

sp|Q9ULW3|ABT1_HUMAN
Activator of basal transcription 1
Search

ABT1

0.97	Activator of basal transcription 1

0.51	GO:0034462	small-subunit processome assembly
0.49	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0021522	spinal cord motor neuron differentiation
0.45	GO:0006366	transcription by RNA polymerase II
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0015074	DNA integration
0.32	GO:0006310	DNA recombination
0.32	GO:0005975	carbohydrate metabolic process

0.51	GO:0003676	nucleic acid binding
0.35	GO:0003713	transcription coactivator activity
0.34	GO:0005515	protein binding
0.32	GO:0004683	calmodulin-dependent protein kinase activity
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0005509	calcium ion binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005730	nucleolus
0.45	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:2.7.11.17

GO:0004683

sp|Q9ULW5|RAB26_HUMAN
Ras-related protein Rab-26
Search

RAB26

0.89	Putative rab subfamily protein of small gtpase

0.56	GO:0043001	Golgi to plasma membrane protein transport
0.56	GO:0035272	exocrine system development
0.55	GO:0045055	regulated exocytosis
0.46	GO:0017157	regulation of exocytosis
0.45	GO:0006904	vesicle docking involved in exocytosis
0.42	GO:0009306	protein secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity

0.56	GO:0030667	secretory granule membrane
0.51	GO:0000139	Golgi membrane
0.45	GO:0008021	synaptic vesicle
0.43	GO:0005768	endosome
0.38	GO:0005886	plasma membrane
0.38	GO:0030658	transport vesicle membrane
0.30	GO:0044425	membrane part

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|Q9ULW6|NP1L2_HUMAN
Nucleosome assembly protein 1-like 2
Search

NAP1L2

0.79	Brain-specific protein, X-linked

0.79	GO:0006334	nucleosome assembly
0.61	GO:0071442	positive regulation of histone H3-K14 acetylation
0.60	GO:2000035	regulation of stem cell division
0.59	GO:2000617	positive regulation of histone H3-K9 acetylation
0.55	GO:0045666	positive regulation of neuron differentiation
0.36	GO:0002244	hematopoietic progenitor cell differentiation
0.34	GO:0001878	response to yeast

0.54	GO:0042393	histone binding
0.53	GO:0003682	chromatin binding

0.61

GO:0005634

nucleus

sp|Q9ULW8|PADI3_HUMAN
Protein-arginine deiminase type-3
Search

PADI3

0.92	Peptidylarginine deiminase type III

0.81	GO:0018101	protein citrullination
0.53	GO:0016570	histone modification
0.52	GO:0019546	arginine deiminase pathway
0.48	GO:0019827	stem cell population maintenance
0.47	GO:0006338	chromatin remodeling
0.47	GO:0006334	nucleosome assembly
0.37	GO:0010848	regulation of chromatin disassembly
0.37	GO:1901624	negative regulation of lymphocyte chemotaxis
0.37	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.36	GO:0045087	innate immune response

0.79	GO:0004668	protein-arginine deiminase activity
0.69	GO:0005509	calcium ion binding
0.54	GO:0042802	identical protein binding
0.48	GO:0016990	arginine deiminase activity
0.47	GO:0034618	arginine binding
0.43	GO:0046983	protein dimerization activity
0.36	GO:0030331	estrogen receptor binding

0.48	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.40	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.34	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.79

EC:3.5.3.15

GO:0004668

sp|Q9ULX3|NOB1_HUMAN
RNA-binding protein NOB1
Search

NOB1

0.92	RNA-binding protein NOB1

0.80	GO:0000469	cleavage involved in rRNA processing
0.72	GO:0042274	ribosomal small subunit biogenesis
0.69	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.59	GO:0007601	visual perception
0.34	GO:0007026	negative regulation of microtubule depolymerization
0.34	GO:0007050	cell cycle arrest
0.34	GO:0030178	negative regulation of Wnt signaling pathway
0.34	GO:0000281	mitotic cytokinesis
0.34	GO:0008285	negative regulation of cell proliferation
0.34	GO:0043065	positive regulation of apoptotic process

0.69	GO:0004521	endoribonuclease activity
0.52	GO:0046872	metal ion binding
0.34	GO:0008013	beta-catenin binding

0.50	GO:0030688	preribosome, small subunit precursor
0.38	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:1905369	endopeptidase complex
0.34	GO:0005829	cytosol
0.34	GO:0044446	intracellular organelle part
0.33	GO:0043234	protein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q9ULX5|RN112_HUMAN
RING finger protein 112
Search

RNF112

0.97	RING finger protein 112

0.60	GO:0045687	positive regulation of glial cell differentiation
0.59	GO:0071158	positive regulation of cell cycle arrest
0.57	GO:0045666	positive regulation of neuron differentiation
0.35	GO:0016567	protein ubiquitination
0.34	GO:0006855	drug transmembrane transport
0.32	GO:0016558	protein import into peroxisome matrix
0.32	GO:0045087	innate immune response
0.32	GO:0051607	defense response to virus
0.32	GO:0006914	autophagy

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0015238	drug transmembrane transporter activity
0.34	GO:0015297	antiporter activity
0.31	GO:0030554	adenyl nucleotide binding

0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.32	GO:0031301	integral component of organelle membrane
0.32	GO:0098805	whole membrane
0.32	GO:0098588	bounding membrane of organelle
0.31	GO:0044446	intracellular organelle part

0.35

GO:0004842

sp|Q9ULX6|AKP8L_HUMAN
A-kinase anchor protein 8-like
Search

AKAP8L

0.89	A-kinase anchoring protein 8 like

0.61	GO:0051081	nuclear envelope disassembly
0.61	GO:0033127	regulation of histone phosphorylation
0.60	GO:0031065	positive regulation of histone deacetylation
0.60	GO:0010793	regulation of mRNA export from nucleus
0.58	GO:0044839	cell cycle G2/M phase transition
0.57	GO:0007076	mitotic chromosome condensation
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0006397	mRNA processing
0.49	GO:0016310	phosphorylation
0.35	GO:0008380	RNA splicing

0.60	GO:0005521	lamin binding
0.58	GO:0042826	histone deacetylase binding
0.55	GO:0003677	DNA binding
0.51	GO:0016301	kinase activity
0.49	GO:0017151	DEAD/H-box RNA helicase binding
0.48	GO:0034237	protein kinase A regulatory subunit binding
0.35	GO:0003723	RNA binding
0.34	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.51	GO:0000785	chromatin
0.49	GO:0031974	membrane-enclosed lumen
0.46	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0005737	cytoplasm

sp|Q9ULX7|CAH14_HUMAN
Carbonic anhydrase 14
Search

CA14

0.94	Carbonic anhydrase XIV

0.50	GO:0006730	one-carbon metabolic process
0.41	GO:0055064	chloride ion homeostasis
0.39	GO:0015670	carbon dioxide transport
0.37	GO:0015701	bicarbonate transport
0.37	GO:0006885	regulation of pH
0.34	GO:0002009	morphogenesis of an epithelium
0.33	GO:0046903	secretion

0.65	GO:0004089	carbonate dehydratase activity
0.46	GO:0008270	zinc ion binding

0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:4.2.1.1

GO:0004089

sp|Q9ULX9|MAFF_HUMAN
Transcription factor MafF
Search

MAFF

0.93	Transcription factor MafF

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.47	GO:0045604	regulation of epidermal cell differentiation
0.47	GO:0035914	skeletal muscle cell differentiation
0.46	GO:0001701	in utero embryonic development
0.43	GO:0051254	positive regulation of RNA metabolic process
0.43	GO:0010557	positive regulation of macromolecule biosynthetic process
0.43	GO:0031328	positive regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part

sp|Q9ULY5|CLC4E_HUMAN
C-type lectin domain family 4 member E
Search

CLEC4E

0.90	Macrophage-inducible C-type lectin

0.57	GO:0038094	Fc-gamma receptor signaling pathway
0.55	GO:0002292	T cell differentiation involved in immune response
0.55	GO:0050715	positive regulation of cytokine secretion
0.53	GO:0045087	innate immune response
0.51	GO:0098542	defense response to other organism
0.51	GO:0009617	response to bacterium
0.41	GO:0002250	adaptive immune response
0.40	GO:0048584	positive regulation of response to stimulus
0.40	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.40	GO:0009620	response to fungus

0.68	GO:0030246	carbohydrate binding
0.44	GO:0004872	receptor activity
0.39	GO:0034987	immunoglobulin receptor binding
0.36	GO:0005540	hyaluronic acid binding
0.34	GO:0001871	pattern binding
0.33	GO:0046872	metal ion binding
0.32	GO:1901265	nucleoside phosphate binding

0.36	GO:0005886	plasma membrane
0.34	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

sp|Q9ULZ0|T53G3_HUMAN
TP53-target gene 3 protein
Search

0.25	TP53-target gene 3 protein (Fragment)

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

sp|Q9ULZ1|APEL_HUMAN
Apelin
Search

APLN

0.97

Apelin

0.76	GO:0010469	regulation of receptor activity
0.74	GO:1904022	positive regulation of G-protein coupled receptor internalization
0.73	GO:0060183	apelin receptor signaling pathway
0.70	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.70	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.69	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.69	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.68	GO:0060976	coronary vasculature development
0.58	GO:0042756	drinking behavior
0.56	GO:0045776	negative regulation of blood pressure

0.88	GO:0031704	apelin receptor binding
0.79	GO:0005179	hormone activity

0.56	GO:0005576	extracellular region
0.49	GO:0048471	perinuclear region of cytoplasm

sp|Q9ULZ2|STAP1_HUMAN
Signal-transducing adaptor protein 1
Search

STAP1

0.97	Signal-transducing adaptor protein 1

0.88	GO:1904149	regulation of microglial cell mediated cytotoxicity
0.88	GO:1904140	negative regulation of microglial cell migration
0.88	GO:1903997	positive regulation of non-membrane spanning protein tyrosine kinase activity
0.88	GO:1903973	negative regulation of cellular response to macrophage colony-stimulating factor stimulus
0.88	GO:1902226	regulation of macrophage colony-stimulating factor signaling pathway
0.87	GO:1900028	negative regulation of ruffle assembly
0.87	GO:1903980	positive regulation of microglial cell activation
0.87	GO:0010760	negative regulation of macrophage chemotaxis
0.87	GO:1905155	positive regulation of membrane invagination
0.87	GO:0050861	positive regulation of B cell receptor signaling pathway

0.87	GO:0005157	macrophage colony-stimulating factor receptor binding
0.87	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity
0.85	GO:0001784	phosphotyrosine residue binding
0.85	GO:0005070	SH3/SH2 adaptor activity
0.40	GO:0005543	phospholipid binding

0.70	GO:0005654	nucleoplasm
0.61	GO:0005739	mitochondrion
0.60	GO:0043234	protein complex

sp|Q9ULZ3|ASC_HUMAN
Apoptosis-associated speck-like protein containing a CARD
Search

PYCARD

0.90	Apoptosis-associated speck-like protein containing a CARD

0.80	GO:0006954	inflammatory response
0.79	GO:0045087	innate immune response
0.74	GO:0042981	regulation of apoptotic process
0.66	GO:0002582	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.66	GO:0002585	positive regulation of antigen processing and presentation of peptide antigen
0.65	GO:0002277	myeloid dendritic cell activation involved in immune response
0.64	GO:0044351	macropinocytosis
0.63	GO:0050718	positive regulation of interleukin-1 beta secretion
0.62	GO:0042104	positive regulation of activated T cell proliferation
0.62	GO:2000406	positive regulation of T cell migration

0.66	GO:0032090	Pyrin domain binding
0.63	GO:0017024	myosin I binding
0.61	GO:0070700	BMP receptor binding
0.60	GO:0005138	interleukin-6 receptor binding
0.58	GO:0005523	tropomyosin binding
0.58	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:0002020	protease binding
0.55	GO:0042803	protein homodimerization activity
0.51	GO:0044325	ion channel binding
0.50	GO:0016505	peptidase activator activity involved in apoptotic process

0.64	GO:0097169	AIM2 inflammasome complex
0.64	GO:0072559	NLRP3 inflammasome complex
0.62	GO:0072558	NLRP1 inflammasome complex
0.60	GO:0008385	IkappaB kinase complex
0.52	GO:0005730	nucleolus
0.49	GO:0043025	neuronal cell body
0.48	GO:0005576	extracellular region
0.47	GO:0005739	mitochondrion
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0035578	azurophil granule lumen

sp|Q9ULZ9|MMP17_HUMAN
Matrix metalloproteinase-17
Search

MMP17

0.75	Matrix metalloproteinase

0.60	GO:0006508	proteolysis
0.52	GO:0042756	drinking behavior
0.48	GO:0001822	kidney development
0.35	GO:0043085	positive regulation of catalytic activity
0.32	GO:0006468	protein phosphorylation

0.69	GO:0004222	metalloendopeptidase activity
0.62	GO:0008270	zinc ion binding
0.35	GO:0070006	metalloaminopeptidase activity
0.35	GO:0008047	enzyme activator activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0031012	extracellular matrix
0.37	GO:0031225	anchored component of membrane
0.34	GO:0005887	integral component of plasma membrane

0.69

GO:0004222

sp|Q9UM00|TMCO1_HUMAN
Calcium load-activated calcium channel
Search

TMCO1

0.88	Calcium load-activated calcium channel

0.85	GO:0032469	endoplasmic reticulum calcium ion homeostasis
0.77	GO:0070588	calcium ion transmembrane transport
0.43	GO:0006983	ER overload response

0.80

GO:0005262

calcium channel activity

0.78	GO:0030176	integral component of endoplasmic reticulum membrane
0.39	GO:0000139	Golgi membrane

sp|Q9UM01|YLAT1_HUMAN
Y+L amino acid transporter 1
Search

SLC7A7

0.88	Y+L system cationic amino acid transporter

0.59	GO:0000821	regulation of arginine metabolic process
0.55	GO:1990822	basic amino acid transmembrane transport
0.49	GO:1902475	L-alpha-amino acid transmembrane transport
0.45	GO:0014005	microglia development
0.35	GO:0050900	leukocyte migration
0.34	GO:0006461	protein complex assembly
0.33	GO:0006520	cellular amino acid metabolic process
0.33	GO:0006468	protein phosphorylation

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005887	integral component of plasma membrane
0.41	GO:0016323	basolateral plasma membrane
0.38	GO:0043231	intracellular membrane-bounded organelle

sp|Q9UM07|PADI4_HUMAN
Protein-arginine deiminase type-4
Search

0.90	Peptidylarginine deiminase type III

0.81	GO:0018101	protein citrullination
0.57	GO:0019546	arginine deiminase pathway
0.55	GO:0016570	histone modification
0.53	GO:0019827	stem cell population maintenance
0.52	GO:0006338	chromatin remodeling
0.51	GO:0006334	nucleosome assembly
0.40	GO:0010848	regulation of chromatin disassembly
0.40	GO:1901624	negative regulation of lymphocyte chemotaxis
0.39	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.39	GO:0030520	intracellular estrogen receptor signaling pathway

0.80	GO:0004668	protein-arginine deiminase activity
0.69	GO:0005509	calcium ion binding
0.54	GO:0042802	identical protein binding
0.53	GO:0016990	arginine deiminase activity
0.52	GO:0034618	arginine binding
0.46	GO:0046983	protein dimerization activity
0.39	GO:0030331	estrogen receptor binding

0.49	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.41	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.36	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.80

EC:3.5.3.15

GO:0004668

sp|Q9UM11|FZR1_HUMAN
Fizzy-related protein homolog
Search

FZR1

0.95	Fizzy and cell division cycle 20 related 1

0.83	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.55	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.54	GO:0070306	lens fiber cell differentiation
0.54	GO:0090344	negative regulation of cell aging
0.53	GO:0040020	regulation of meiotic nuclear division
0.52	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.51	GO:0045732	positive regulation of protein catabolic process
0.50	GO:0008284	positive regulation of cell proliferation
0.42	GO:0051301	cell division
0.36	GO:1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation

0.84	GO:0097027	ubiquitin-protein transferase activator activity
0.84	GO:0010997	anaphase-promoting complex binding

0.51	GO:0005680	anaphase-promoting complex
0.51	GO:0031965	nuclear membrane
0.47	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

sp|Q9UM13|APC10_HUMAN
Anaphase-promoting complex subunit 10
Search

ANAPC10

0.78	Anaphase-promoting complex subunit 10

0.82	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.64	GO:0051301	cell division
0.63	GO:0007049	cell cycle
0.59	GO:0070979	protein K11-linked ubiquitination
0.48	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.35	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.35	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.34	GO:1901990	regulation of mitotic cell cycle phase transition

0.46	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding

0.79	GO:0005680	anaphase-promoting complex
0.38	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|Q9UM19|HPCL4_HUMAN
Hippocalcin-like protein 4
Search

HPCAL4

0.97	Hippocalcin like 4

0.53	GO:0065009	regulation of molecular function
0.50	GO:0007165	signal transduction
0.47	GO:0046676	negative regulation of insulin secretion
0.47	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.46	GO:0045921	positive regulation of exocytosis
0.34	GO:0007417	central nervous system development

0.70	GO:0005509	calcium ion binding
0.66	GO:0005246	calcium channel regulator activity
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q9UM21|MGT4A_HUMAN
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
Search

MGAT4A

0.93	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

0.60	GO:0005975	carbohydrate metabolic process
0.55	GO:0006487	protein N-linked glycosylation
0.35	GO:0006491	N-glycan processing
0.35	GO:0043687	post-translational protein modification

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.52	GO:0008194	UDP-glycosyltransferase activity
0.43	GO:0140103	catalytic activity, acting on a glycoprotein
0.36	GO:0046872	metal ion binding

0.41	GO:0000139	Golgi membrane
0.38	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016758

sp|Q9UM22|EPDR1_HUMAN
Mammalian ependymin-related protein 1
Search

EPDR1

0.96	Mammalian ependymin related protein 1

0.82

GO:0007160

cell-matrix adhesion

0.70

GO:0005509

calcium ion binding

0.66	GO:0005576	extracellular region
0.59	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UM44|HHLA2_HUMAN
HERV-H LTR-associating protein 2
Search

HHLA2

0.93	HERV-H LTR-associating protein 2

0.66	GO:0042104	positive regulation of activated T cell proliferation
0.66	GO:0031295	T cell costimulation
0.62	GO:0001819	positive regulation of cytokine production
0.37	GO:0045077	negative regulation of interferon-gamma biosynthetic process
0.37	GO:0045085	negative regulation of interleukin-2 biosynthetic process
0.36	GO:1900040	regulation of interleukin-2 secretion
0.36	GO:0030501	positive regulation of bone mineralization
0.36	GO:0042130	negative regulation of T cell proliferation
0.36	GO:0045669	positive regulation of osteoblast differentiation
0.36	GO:0050728	negative regulation of inflammatory response

0.38

GO:0005515

protein binding

0.35	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9UM47|NOTC3_HUMAN
Neurogenic locus notch homolog protein 3
Search

NOTCH3

0.91	Notch homolog 3

0.81	GO:0007219	Notch signaling pathway
0.71	GO:0030154	cell differentiation
0.69	GO:0007275	multicellular organism development
0.66	GO:0050793	regulation of developmental process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0009653	anatomical structure morphogenesis
0.53	GO:0060322	head development
0.51	GO:0035633	maintenance of permeability of blood-brain barrier

0.69	GO:0005509	calcium ion binding
0.63	GO:0004872	receptor activity
0.47	GO:0045296	cadherin binding
0.45	GO:0042802	identical protein binding
0.42	GO:0019899	enzyme binding
0.34	GO:0004871	signal transducer activity
0.34	GO:0051059	NF-kappaB binding
0.33	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.52	GO:0043235	receptor complex
0.48	GO:0005654	nucleoplasm
0.45	GO:0015629	actin cytoskeleton
0.44	GO:0009986	cell surface
0.43	GO:0005829	cytosol
0.41	GO:0005887	integral component of plasma membrane
0.33	GO:0005576	extracellular region
0.33	GO:0000139	Golgi membrane
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005929	cilium

sp|Q9UM54|MYO6_HUMAN
Unconventional myosin-VI
Search

MYO6

0.94	Unconventional myosin-VI

0.74	GO:0007018	microtubule-based movement
0.53	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.49	GO:0051046	regulation of secretion
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0035479	angioblast cell migration from lateral mesoderm to midline
0.47	GO:0006897	endocytosis
0.45	GO:0048844	artery morphogenesis
0.41	GO:0050954	sensory perception of mechanical stimulus
0.39	GO:0042491	inner ear auditory receptor cell differentiation
0.37	GO:0030048	actin filament-based movement

0.77	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0045296	cadherin binding
0.38	GO:0000146	microfilament motor activity
0.37	GO:0042802	identical protein binding
0.37	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.53	GO:0031941	filamentous actin
0.52	GO:0045334	clathrin-coated endocytic vesicle
0.51	GO:0001726	ruffle
0.50	GO:0031965	nuclear membrane
0.50	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.47	GO:0005794	Golgi apparatus
0.39	GO:0005902	microvillus
0.39	GO:0031256	leading edge membrane

sp|Q9UM63|PLAL1_HUMAN
Zinc finger protein PLAGL1
Search

PLAGL1

0.96	Zinc finger protein PLAGL1

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0006366	transcription by RNA polymerase II
0.41	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0006915	apoptotic process
0.41	GO:0030154	cell differentiation
0.40	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.39	GO:0007050	cell cycle arrest
0.36	GO:0007519	skeletal muscle tissue development

0.78	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.43	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.36	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.44	GO:0016604	nuclear body
0.42	GO:0005794	Golgi apparatus

sp|Q9UM73|ALK_HUMAN
ALK tyrosine kinase receptor
Search

ALK

0.67	Tyrosine-protein kinase receptor

0.79	GO:0000187	activation of MAPK activity
0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0048666	neuron development
0.61	GO:0090648	response to environmental enrichment
0.59	GO:0036269	swimming behavior
0.58	GO:0060159	regulation of dopamine receptor signaling pathway
0.56	GO:0021766	hippocampus development
0.55	GO:0030534	adult behavior
0.53	GO:0046777	protein autophosphorylation

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042802	identical protein binding
0.37	GO:0004704	NF-kappaB-inducing kinase activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0030276	clathrin binding
0.33	GO:0035091	phosphatidylinositol binding

0.47	GO:0005887	integral component of plasma membrane
0.44	GO:0043234	protein complex
0.38	GO:0070062	extracellular exosome
0.35	GO:0044297	cell body
0.35	GO:0030424	axon
0.34	GO:0030136	clathrin-coated vesicle

0.80

EC:2.7.10.1

GO:0004714

sp|Q9UM82|SPAT2_HUMAN
Spermatogenesis-associated protein 2
Search

SPATA2

0.97	Spermatogenesis-associated protein 2

0.40	GO:0007283	spermatogenesis
0.39	GO:0030154	cell differentiation
0.38	GO:0007275	multicellular organism development
0.37	GO:0007601	visual perception
0.36	GO:0018298	protein-chromophore linkage
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.38	GO:0008270	zinc ion binding
0.37	GO:0009881	photoreceptor activity
0.37	GO:0005515	protein binding
0.36	GO:0004930	G-protein coupled receptor activity

0.80	GO:0001650	fibrillar center
0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9UMD9|COHA1_HUMAN
Collagen alpha-1(XVII) chain
Search

COL17A1

0.95	Collagen type XVII alpha 1 chain

0.59	GO:0031581	hemidesmosome assembly
0.40	GO:0048925	lateral line system development
0.37	GO:0008544	epidermis development
0.33	GO:0007160	cell-matrix adhesion
0.33	GO:0050776	regulation of immune response

0.34

GO:0005515

protein binding

0.66	GO:0005581	collagen trimer
0.59	GO:0030056	hemidesmosome
0.41	GO:0005604	basement membrane
0.33	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005911	cell-cell junction
0.32	GO:0005887	integral component of plasma membrane

sp|Q9UMF0|ICAM5_HUMAN
Intercellular adhesion molecule 5
Search

ICAM5

0.88	Intercellular adhesion molecule 5

0.76	GO:0098609	cell-cell adhesion
0.53	GO:0006909	phagocytosis
0.50	GO:0002457	T cell antigen processing and presentation
0.50	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.49	GO:0022614	membrane to membrane docking
0.49	GO:0002693	positive regulation of cellular extravasation
0.48	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.48	GO:0033627	cell adhesion mediated by integrin
0.48	GO:1900027	regulation of ruffle assembly
0.48	GO:0061028	establishment of endothelial barrier

0.60	GO:0005178	integrin binding
0.35	GO:0001618	virus receptor activity
0.33	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0003735	structural constituent of ribosome

0.48	GO:0001772	immunological synapse
0.47	GO:0005887	integral component of plasma membrane
0.46	GO:0070062	extracellular exosome
0.46	GO:0009897	external side of plasma membrane
0.46	GO:0098857	membrane microdomain
0.44	GO:0031012	extracellular matrix
0.34	GO:0005925	focal adhesion
0.34	GO:0001931	uropod
0.34	GO:0097610	cell surface furrow
0.34	GO:0005902	microvillus

sp|Q9UMN6|KMT2B_HUMAN
Histone-lysine N-methyltransferase 2B
Search

KMT2B

0.45	Histone-lysine N-methyltransferase

0.76	GO:0051568	histone H3-K4 methylation
0.72	GO:0030728	ovulation
0.70	GO:0051569	regulation of histone H3-K4 methylation
0.69	GO:0018023	peptidyl-lysine trimethylation
0.69	GO:0001541	ovarian follicle development
0.68	GO:0009994	oocyte differentiation
0.68	GO:0007613	memory
0.63	GO:0016458	gene silencing
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.78	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.61	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.39	GO:0005199	structural constituent of cell wall
0.36	GO:0005515	protein binding
0.36	GO:0003700	DNA binding transcription factor activity

0.73	GO:0035097	histone methyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UMQ3|BARX2_HUMAN
Homeobox protein BarH-like 2
Search

BARX2

0.97	BARX homeobox 2

0.63	GO:0001502	cartilage condensation
0.60	GO:0014902	myotube differentiation
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006366	transcription by RNA polymerase II
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0007399	nervous system development
0.48	GO:0055123	digestive system development
0.48	GO:0048536	spleen development
0.47	GO:0030178	negative regulation of Wnt signaling pathway
0.46	GO:0009952	anterior/posterior pattern specification

0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.56	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.54	GO:0005667	transcription factor complex
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part

sp|Q9UMQ6|CAN11_HUMAN
Calpain-11
Search

CAPN11

0.87	Calpain-1 catalytic subunit

0.61	GO:0006508	proteolysis
0.48	GO:0007586	digestion
0.47	GO:0051493	regulation of cytoskeleton organization
0.39	GO:0007520	myoblast fusion
0.39	GO:0071230	cellular response to amino acid stimulus
0.38	GO:0001824	blastocyst development
0.38	GO:0021785	branchiomotor neuron axon guidance
0.37	GO:0044257	cellular protein catabolic process
0.37	GO:0007420	brain development
0.35	GO:0043066	negative regulation of apoptotic process

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.69	GO:0005509	calcium ion binding

0.52	GO:0001669	acrosomal vesicle
0.39	GO:0031143	pseudopodium
0.39	GO:0097038	perinuclear endoplasmic reticulum
0.38	GO:0045121	membrane raft
0.38	GO:0005764	lysosome
0.37	GO:0005829	cytosol
0.37	GO:0000785	chromatin
0.37	GO:0005794	Golgi apparatus
0.35	GO:0005634	nucleus
0.35	GO:0005886	plasma membrane

sp|Q9UMR2|DD19B_HUMAN
ATP-dependent RNA helicase DDX19B
Search

DDX19B

0.83	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b

0.56	GO:0010501	RNA secondary structure unwinding
0.52	GO:0008380	RNA splicing
0.43	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0010043	response to zinc ion
0.39	GO:0043065	positive regulation of apoptotic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0004004	ATP-dependent RNA helicase activity
0.51	GO:0003676	nucleic acid binding

0.56	GO:0071013	catalytic step 2 spliceosome
0.51	GO:0005730	nucleolus
0.48	GO:0070062	extracellular exosome
0.41	GO:0005635	nuclear envelope
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9UMR3|TBX20_HUMAN
T-box transcription factor TBX20
Search

TBX20

0.82	T-box transcription factor TBX20

0.65	GO:0060577	pulmonary vein morphogenesis
0.65	GO:0035922	foramen ovale closure
0.64	GO:0036306	embryonic heart tube elongation
0.64	GO:0003180	aortic valve morphogenesis
0.63	GO:0001947	heart looping
0.63	GO:0003193	pulmonary valve formation
0.63	GO:0021524	visceral motor neuron differentiation
0.62	GO:0010991	negative regulation of SMAD protein complex assembly
0.62	GO:0060413	atrial septum morphogenesis
0.62	GO:0003175	tricuspid valve development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001105	RNA polymerase II transcription coactivator activity
0.59	GO:0001102	RNA polymerase II activating transcription factor binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9UMR5|PPT2_HUMAN
Lysosomal thioesterase PPT2
Search

PPT2

0.94	Palmitoyl-protein thioesterase 2

0.85	GO:0098734	macromolecule depalmitoylation
0.36	GO:0046949	fatty-acyl-CoA biosynthetic process

0.85	GO:0008474	palmitoyl-(protein) hydrolase activity
0.34	GO:0005509	calcium ion binding

0.39	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.35	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.1.2.22

GO:0008474

sp|Q9UMR7|CLC4A_HUMAN
C-type lectin domain family 4 member A
Search

0.89	C-type lectin domain containing 6A

0.44	GO:0045087	innate immune response
0.43	GO:0002768	immune response-regulating cell surface receptor signaling pathway
0.41	GO:0002250	adaptive immune response
0.41	GO:0051050	positive regulation of transport
0.41	GO:0002366	leukocyte activation involved in immune response
0.40	GO:0050707	regulation of cytokine secretion
0.40	GO:0001819	positive regulation of cytokine production
0.39	GO:1904951	positive regulation of establishment of protein localization
0.39	GO:0030217	T cell differentiation
0.39	GO:0002758	innate immune response-activating signal transduction

0.68	GO:0030246	carbohydrate binding
0.38	GO:0004872	receptor activity
0.35	GO:0004871	signal transducer activity
0.34	GO:0070001	aspartic-type peptidase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0004175	endopeptidase activity
0.33	GO:0097367	carbohydrate derivative binding

0.36	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0070821	tertiary granule membrane
0.35	GO:0005887	integral component of plasma membrane

sp|Q9UMS0|NFU1_HUMAN
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
Search

0.55	HIRA interacting protein 5

0.74	GO:0031163	metallo-sulfur cluster assembly
0.65	GO:0006790	sulfur compound metabolic process
0.63	GO:0051188	cofactor biosynthetic process
0.34	GO:0006470	protein dephosphorylation
0.33	GO:1901135	carbohydrate derivative metabolic process
0.32	GO:0006468	protein phosphorylation
0.32	GO:1901576	organic substance biosynthetic process

0.64	GO:0051536	iron-sulfur cluster binding
0.63	GO:0005506	iron ion binding
0.35	GO:0008483	transaminase activity
0.34	GO:0005515	protein binding
0.34	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0097367	carbohydrate derivative binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.6.1

GO:0008483

sp|Q9UMS4|PRP19_HUMAN
Pre-mRNA-processing factor 19
Search

PRPF19

0.90	Pre-mRNA processing factor 19

0.69	GO:0016567	protein ubiquitination
0.57	GO:0048711	positive regulation of astrocyte differentiation
0.56	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.56	GO:0072422	signal transduction involved in DNA damage checkpoint
0.56	GO:0000244	spliceosomal tri-snRNP complex assembly
0.55	GO:0001833	inner cell mass cell proliferation
0.54	GO:0045665	negative regulation of neuron differentiation
0.54	GO:0000245	spliceosomal complex assembly
0.53	GO:0006303	double-strand break repair via nonhomologous end joining
0.51	GO:0010498	proteasomal protein catabolic process

0.70	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0061659	ubiquitin-like protein ligase activity
0.50	GO:0042802	identical protein binding

0.57	GO:0000974	Prp19 complex
0.56	GO:0005662	DNA replication factor A complex
0.55	GO:0071007	U2-type catalytic step 2 spliceosome
0.55	GO:0035861	site of double-strand break
0.54	GO:0005811	lipid droplet
0.53	GO:0016607	nuclear speck
0.48	GO:0071006	U2-type catalytic step 1 spliceosome
0.40	GO:0005819	spindle
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.70

GO:0004842

sp|Q9UMS5|PHTF1_HUMAN
Putative homeodomain transcription factor 1
Search

PHTF1

0.97	Putative homeodomain transcription factor 1

0.35	GO:0007283	spermatogenesis
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.47	GO:0003677	DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.40	GO:0005801	cis-Golgi network
0.39	GO:0005783	endoplasmic reticulum
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9UMS6|SYNP2_HUMAN
Synaptopodin-2
Search

SYNPO2

0.97	Synaptopodin 2 variant

0.66	GO:0032233	positive regulation of actin filament bundle assembly
0.50	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity
0.47	GO:0000045	autophagosome assembly
0.46	GO:0030335	positive regulation of cell migration
0.38	GO:1904622	negative regulation of actin-dependent ATPase activity
0.38	GO:1904617	negative regulation of actin binding
0.38	GO:1904529	regulation of actin filament binding
0.38	GO:0031034	myosin filament assembly
0.32	GO:0032259	methylation

0.84	GO:0031005	filamin binding
0.83	GO:0051393	alpha-actinin binding
0.59	GO:0003779	actin binding
0.49	GO:0071889	14-3-3 protein binding
0.37	GO:0017022	myosin binding
0.36	GO:0032403	protein complex binding
0.32	GO:0008168	methyltransferase activity

0.83	GO:0030018	Z disc
0.81	GO:0097517	contractile actin filament bundle
0.81	GO:0042641	actomyosin
0.77	GO:0005925	focal adhesion
0.66	GO:0005829	cytosol
0.55	GO:0043231	intracellular membrane-bounded organelle
0.45	GO:0099023	tethering complex
0.37	GO:0005884	actin filament
0.33	GO:0043233	organelle lumen

0.32

GO:0008168

sp|Q9UMW8|UBP18_HUMAN
Ubl carboxyl-terminal hydrolase 18
Search

USP18

0.97	Ubl carboxyl-terminal hydrolase 18

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.50	GO:0050727	regulation of inflammatory response
0.43	GO:0035634	response to stilbenoid
0.38	GO:0060338	regulation of type I interferon-mediated signaling pathway

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.48	GO:0019785	ISG15-specific protease activity
0.37	GO:0005515	protein binding

0.42	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0036459

sp|Q9UMX0|UBQL1_HUMAN
Ubiquilin-1
Search

UBQLN1

0.92	Retina ubiquilin

0.87	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process
0.82	GO:1901340	negative regulation of store-operated calcium channel activity
0.81	GO:0030433	ubiquitin-dependent ERAD pathway
0.79	GO:0035973	aggrephagy
0.78	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway
0.75	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.74	GO:0097352	autophagosome maturation
0.72	GO:0071456	cellular response to hypoxia
0.71	GO:0000045	autophagosome assembly
0.71	GO:0031398	positive regulation of protein ubiquitination

0.73	GO:0031593	polyubiquitin modification-dependent protein binding
0.67	GO:0019900	kinase binding
0.64	GO:0042802	identical protein binding
0.40	GO:0019215	intermediate filament binding
0.37	GO:0019904	protein domain specific binding
0.37	GO:0005102	receptor binding
0.35	GO:0016746	transferase activity, transferring acyl groups

0.74	GO:0016235	aggresome
0.74	GO:0005776	autophagosome
0.68	GO:0048471	perinuclear region of cytoplasm
0.67	GO:0005829	cytosol
0.62	GO:0005783	endoplasmic reticulum
0.60	GO:0005654	nucleoplasm
0.55	GO:0005886	plasma membrane
0.53	GO:0043234	protein complex
0.46	GO:0031410	cytoplasmic vesicle
0.44	GO:1905369	endopeptidase complex

0.35

GO:0016746

sp|Q9UMX1|SUFU_HUMAN
Suppressor of fused homolog
Search

SUFU

0.94	Suppressor of fused homolog

0.56	GO:0045879	negative regulation of smoothened signaling pathway
0.55	GO:0007224	smoothened signaling pathway
0.54	GO:0007275	multicellular organism development
0.54	GO:0042994	cytoplasmic sequestering of transcription factor
0.53	GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.52	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.52	GO:0045992	negative regulation of embryonic development
0.50	GO:0001708	cell fate specification
0.49	GO:0051961	negative regulation of nervous system development
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II

0.70	GO:0008134	transcription factor binding
0.50	GO:0008013	beta-catenin binding
0.49	GO:0019901	protein kinase binding
0.44	GO:0003714	transcription corepressor activity
0.39	GO:0004871	signal transducer activity
0.32	GO:0003676	nucleic acid binding

0.54	GO:0005634	nucleus
0.47	GO:0005929	cilium
0.47	GO:0035301	Hedgehog signaling complex
0.44	GO:0005737	cytoplasm
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0044422	organelle part

sp|Q9UMX2|OAZ3_HUMAN
Ornithine decarboxylase antizyme 3
Search

OAZ3

0.46	LOW QUALITY PROTEIN: ornithine decarboxylase antizyme 3

0.80	GO:0007283	spermatogenesis
0.72	GO:0043086	negative regulation of catalytic activity
0.53	GO:0045732	positive regulation of protein catabolic process
0.51	GO:0006595	polyamine metabolic process
0.46	GO:1902268	negative regulation of polyamine transmembrane transport
0.43	GO:0015847	putrescine transport
0.40	GO:0090316	positive regulation of intracellular protein transport
0.39	GO:0042401	cellular biogenic amine biosynthetic process
0.38	GO:0006521	regulation of cellular amino acid metabolic process
0.37	GO:0043666	regulation of phosphoprotein phosphatase activity

0.85	GO:0008073	ornithine decarboxylase inhibitor activity
0.43	GO:0015489	putrescine transmembrane transporter activity
0.39	GO:0071532	ankyrin repeat binding

0.58	GO:0005654	nucleoplasm
0.41	GO:0072562	blood microparticle
0.39	GO:0005737	cytoplasm
0.38	GO:0036126	sperm flagellum

sp|Q9UMX3|BOK_HUMAN
Bcl-2-related ovarian killer protein
Search

BOK

0.97	Putative anti-apoptotic bcl-2 family prevent opening of mitochondrial porin channel

0.74	GO:0042981	regulation of apoptotic process
0.59	GO:0051902	negative regulation of mitochondrial depolarization
0.59	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.59	GO:1901382	regulation of chorionic trophoblast cell proliferation
0.58	GO:0060546	negative regulation of necroptotic process
0.58	GO:0006915	apoptotic process
0.56	GO:0010823	negative regulation of mitochondrion organization
0.56	GO:0070997	neuron death
0.56	GO:0046902	regulation of mitochondrial membrane permeability
0.55	GO:2001056	positive regulation of cysteine-type endopeptidase activity

0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0042803	protein homodimerization activity
0.50	GO:0005102	receptor binding
0.46	GO:0046982	protein heterodimerization activity
0.42	GO:0051400	BH domain binding
0.34	GO:0004197	cysteine-type endopeptidase activity

0.59	GO:0033106	cis-Golgi network membrane
0.56	GO:0032588	trans-Golgi network membrane
0.56	GO:0055038	recycling endosome membrane
0.56	GO:0031901	early endosome membrane
0.50	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0031966	mitochondrial membrane
0.46	GO:0031968	organelle outer membrane
0.45	GO:0019866	organelle inner membrane
0.45	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004197

sp|Q9UMX5|NENF_HUMAN
Neudesin
Search

NENF

0.96	Neuron derived neurotrophic factor

0.80	GO:0032099	negative regulation of appetite
0.72	GO:0043410	positive regulation of MAPK cascade
0.68	GO:0010469	regulation of receptor activity

0.70	GO:0008083	growth factor activity
0.39	GO:0046872	metal ion binding

0.66	GO:0005615	extracellular space
0.63	GO:0005654	nucleoplasm
0.56	GO:0012505	endomembrane system
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UMX6|GUC1B_HUMAN
Guanylyl cyclase-activating protein 2
Search

GUCA1B

0.97	Guanylate cyclase activating protein 2

0.63	GO:0031284	positive regulation of guanylate cyclase activity
0.53	GO:0007601	visual perception
0.53	GO:0007602	phototransduction
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:0007589	body fluid secretion
0.34	GO:0007267	cell-cell signaling

0.70	GO:0005509	calcium ion binding
0.64	GO:0008048	calcium sensitive guanylate cyclase activator activity

0.40	GO:0001917	photoreceptor inner segment
0.39	GO:0001750	photoreceptor outer segment
0.35	GO:0060170	ciliary membrane

sp|Q9UMX9|S45A2_HUMAN
Membrane-associated transporter protein
Search

SLC45A2

0.90	Membrane-associated transporter protein isoform a

0.47	GO:0048066	developmental pigmentation
0.47	GO:0015770	sucrose transport
0.43	GO:0042438	melanin biosynthetic process
0.41	GO:0007601	visual perception
0.40	GO:0055085	transmembrane transport
0.37	GO:0050896	response to stimulus
0.35	GO:0030154	cell differentiation

0.48

GO:0008506

sucrose:proton symporter activity

0.44	GO:0033162	melanosome membrane
0.30	GO:0016021	integral component of membrane

sp|Q9UMY1|NOL7_HUMAN
Nucleolar protein 7
Search

NOL7

0.97	Nucleolar protein 7

0.46	GO:0006937	regulation of muscle contraction
0.38	GO:0036048	protein desuccinylation
0.38	GO:0036046	protein demalonylation
0.37	GO:0006476	protein deacetylation
0.37	GO:0018205	peptidyl-lysine modification
0.34	GO:0072383	plus-end-directed vesicle transport along microtubule

0.38	GO:0036055	protein-succinyllysine desuccinylase activity
0.38	GO:0036054	protein-malonyllysine demalonylase activity
0.38	GO:0070403	NAD+ binding
0.38	GO:0034979	NAD-dependent protein deacetylase activity
0.36	GO:0003723	RNA binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0003777	microtubule motor activity

0.60	GO:0005730	nucleolus
0.52	GO:0005739	mitochondrion
0.47	GO:0005861	troponin complex
0.36	GO:0005829	cytosol

sp|Q9UMY4|SNX12_HUMAN
Sorting nexin-12
Search

SNX12

0.96	Sorting nexin-12

0.56	GO:2000642	negative regulation of early endosome to late endosome transport
0.52	GO:0010955	negative regulation of protein processing
0.52	GO:0042177	negative regulation of protein catabolic process
0.51	GO:0051224	negative regulation of protein transport
0.51	GO:0030100	regulation of endocytosis
0.45	GO:0016050	vesicle organization
0.42	GO:0006897	endocytosis
0.36	GO:0042541	hemoglobin biosynthetic process
0.36	GO:0030218	erythrocyte differentiation
0.35	GO:0022615	protein to membrane docking

0.77	GO:0035091	phosphatidylinositol binding
0.47	GO:0019899	enzyme binding

0.50	GO:0005768	endosome
0.44	GO:0019898	extrinsic component of membrane
0.38	GO:0070062	extracellular exosome
0.35	GO:0032009	early phagosome
0.34	GO:0030904	retromer complex
0.34	GO:0030136	clathrin-coated vesicle
0.34	GO:0044433	cytoplasmic vesicle part
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0005829	cytosol

sp|Q9UMZ2|SYNRG_HUMAN
Synergin gamma
Search

SYNRG

0.96	Synergin gamma

0.69	GO:0006897	endocytosis
0.63	GO:0015031	protein transport
0.61	GO:0046907	intracellular transport
0.61	GO:0034613	cellular protein localization

0.56	GO:0005515	protein binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003676	nucleic acid binding

0.80	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.70	GO:0030131	clathrin adaptor complex

sp|Q9UMZ3|PTPRQ_HUMAN
Phosphatidylinositol phosphatase PTPRQ
Search

PTPRQ

0.62	phosphatidylinositol phosphatase PTPRQ

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.57	GO:0060116	vestibular receptor cell morphogenesis
0.54	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.53	GO:0050885	neuromuscular process controlling balance
0.52	GO:0002244	hematopoietic progenitor cell differentiation
0.36	GO:0045598	regulation of fat cell differentiation
0.32	GO:0048496	maintenance of animal organ identity
0.32	GO:0045494	photoreceptor cell maintenance
0.32	GO:0050953	sensory perception of light stimulus
0.32	GO:0045184	establishment of protein localization

0.74	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0017022	myosin binding
0.32	GO:0005518	collagen binding
0.32	GO:0042803	protein homodimerization activity

0.53	GO:0032421	stereocilium bundle
0.34	GO:0005815	microtubule organizing center
0.34	GO:0005874	microtubule
0.33	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.33	GO:1990696	USH2 complex
0.32	GO:0001917	photoreceptor inner segment
0.32	GO:0032391	photoreceptor connecting cilium
0.32	GO:0098858	actin-based cell projection
0.32	GO:0005604	basement membrane

0.74

GO:0004725

sp|Q9UN19|DAPP1_HUMAN
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
Search

DAPP1

0.97	Dual adapter for phosphotyrosine and 3-phosphotyrosine and

0.43	GO:0038083	peptidyl-tyrosine autophosphorylation
0.41	GO:0045087	innate immune response
0.41	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.41	GO:0016477	cell migration
0.41	GO:0042127	regulation of cell proliferation
0.40	GO:0030154	cell differentiation
0.38	GO:0006470	protein dephosphorylation
0.37	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0007018	microtubule-based movement
0.33	GO:0035023	regulation of Rho protein signal transduction

0.85	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.85	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.61	GO:0030165	PDZ domain binding
0.42	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.40	GO:0005102	receptor binding
0.38	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0008092	cytoskeletal protein binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0032403	protein complex binding

0.55	GO:0005886	plasma membrane
0.41	GO:0098562	cytoplasmic side of membrane
0.41	GO:0019898	extrinsic component of membrane
0.41	GO:0005737	cytoplasm

0.42

EC:2.7.10.2

GO:0004715

sp|Q9UN30|SCML1_HUMAN
Sex comb on midleg-like protein 1
Search

SCML1

0.96	Sex comb on midleg like 1 (Drosophila)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0009952	anterior/posterior pattern specification
0.49	GO:0007283	spermatogenesis
0.48	GO:0006351	transcription, DNA-templated
0.48	GO:0006338	chromatin remodeling
0.40	GO:0009653	anatomical structure morphogenesis
0.36	GO:0036353	histone H2A-K119 monoubiquitination
0.35	GO:0006915	apoptotic process

0.38	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0010369	chromocenter
0.34	GO:0000785	chromatin
0.34	GO:0043234	protein complex
0.34	GO:0031974	membrane-enclosed lumen

sp|Q9UN36|NDRG2_HUMAN
Protein NDRG2
Search

NDRG2

0.97	NDRG family member 2

0.85	GO:0090361	regulation of platelet-derived growth factor production
0.83	GO:0048662	negative regulation of smooth muscle cell proliferation
0.81	GO:0010574	regulation of vascular endothelial growth factor production
0.79	GO:0070372	regulation of ERK1 and ERK2 cascade
0.76	GO:0001818	negative regulation of cytokine production
0.75	GO:0043409	negative regulation of MAPK cascade
0.59	GO:0048513	animal organ development
0.58	GO:0060322	head development
0.57	GO:0007417	central nervous system development
0.51	GO:2001135	regulation of endocytic recycling

0.68	GO:0005794	Golgi apparatus
0.57	GO:0005634	nucleus
0.48	GO:0016323	basolateral plasma membrane
0.48	GO:0031253	cell projection membrane

sp|Q9UN37|VPS4A_HUMAN
Vacuolar protein sorting-associated protein 4A
Search

VPS4A

0.83	LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 4A

0.58	GO:0061738	late endosomal microautophagy
0.56	GO:0036258	multivesicular body assembly
0.52	GO:0048524	positive regulation of viral process
0.47	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
0.46	GO:1903543	positive regulation of exosomal secretion
0.46	GO:1902186	regulation of viral release from host cell
0.46	GO:1903724	positive regulation of centriole elongation
0.45	GO:0000920	cell separation after cytokinesis
0.45	GO:1903542	negative regulation of exosomal secretion
0.45	GO:0007080	mitotic metaphase plate congression

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0008022	protein C-terminus binding
0.42	GO:0016887	ATPase activity
0.41	GO:0042803	protein homodimerization activity
0.37	GO:0019904	protein domain specific binding
0.35	GO:0005198	structural molecule activity
0.34	GO:0017048	Rho GTPase binding

0.49	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0090543	Flemming body
0.43	GO:0000922	spindle pole
0.43	GO:0010008	endosome membrane
0.43	GO:0005813	centrosome
0.43	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.39	GO:0005770	late endosome
0.37	GO:0036452	ESCRT complex
0.37	GO:0005769	early endosome

0.42

GO:0016887

sp|Q9UN42|AT1B4_HUMAN
Protein ATP1B4
Search

ATP1B4

0.80	Sodium/potassium-transporting ATPase subunit beta

0.71	GO:0006814	sodium ion transport
0.70	GO:0006813	potassium ion transport
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903288	positive regulation of potassium ion import
0.36	GO:1903275	positive regulation of sodium ion export
0.36	GO:1903276	regulation of sodium ion export across plasma membrane
0.36	GO:0006883	cellular sodium ion homeostasis

0.37	GO:0005515	protein binding
0.35	GO:0005391	sodium:potassium-exchanging ATPase activity
0.35	GO:0001671	ATPase activator activity
0.33	GO:0005223	intracellular cGMP activated cation channel activity
0.33	GO:0030553	cGMP binding
0.32	GO:0031402	sodium ion binding
0.32	GO:0030955	potassium ion binding
0.32	GO:0005222	intracellular cAMP activated cation channel activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0016301	kinase activity

0.84	GO:0005890	sodium:potassium-exchanging ATPase complex
0.57	GO:0005637	nuclear inner membrane
0.35	GO:0016324	apical plasma membrane
0.34	GO:0000785	chromatin
0.33	GO:0014704	intercalated disc
0.33	GO:0042383	sarcolemma
0.32	GO:0001750	photoreceptor outer segment
0.32	GO:0043209	myelin sheath
0.32	GO:0016323	basolateral plasma membrane
0.32	GO:0017071	intracellular cyclic nucleotide activated cation channel complex

0.35

EC:3.6.3.9

GO:0005391

sp|Q9UN66|PCDB8_HUMAN
Protocadherin beta-8
Search

0.93	Protocadherin beta-8

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.60	GO:0098916	anterograde trans-synaptic signaling
0.51	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UN67|PCDBA_HUMAN
Protocadherin beta-10
Search

0.94	Protocadherin beta-9

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.65	GO:0007416	synapse assembly
0.60	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UN70|PCDGK_HUMAN
Protocadherin gamma-C3
Search

0.89	Protocadherin gamma subfamily C, 3

0.76	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007267	cell-cell signaling
0.52	GO:0007399	nervous system development
0.43	GO:0050808	synapse organization
0.41	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0007283	spermatogenesis
0.35	GO:0060989	lipid tube assembly involved in organelle fusion
0.34	GO:0008333	endosome to lysosome transport

0.68	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.40	GO:0070062	extracellular exosome
0.36	GO:0005911	cell-cell junction
0.36	GO:0030426	growth cone
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9UN71|PCDGG_HUMAN
Protocadherin gamma-B4
Search

0.92	Protocadherin gamma B2-alpha C

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.57	GO:0007267	cell-cell signaling
0.56	GO:0007399	nervous system development
0.40	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0050808	synapse organization
0.36	GO:0060989	lipid tube assembly involved in organelle fusion
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.38	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.40	GO:0030426	growth cone
0.39	GO:0070062	extracellular exosome
0.35	GO:0005911	cell-cell junction
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9UN72|PCDA7_HUMAN
Protocadherin alpha-7
Search

0.92	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.52	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.37	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.41	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0045202	synapse
0.36	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UN73|PCDA6_HUMAN
Protocadherin alpha-6
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.38	GO:0009988	cell-cell recognition
0.37	GO:0042476	odontogenesis
0.37	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0045202	synapse
0.36	GO:0005576	extracellular region
0.36	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q9UN74|PCDA4_HUMAN
Protocadherin alpha-4
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.43	GO:0005783	endoplasmic reticulum
0.37	GO:0005634	nucleus
0.37	GO:0005576	extracellular region
0.36	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UN75|PCDAC_HUMAN
Protocadherin alpha-12
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.38	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.37	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.36	GO:0045202	synapse
0.30	GO:0044425	membrane part

sp|Q9UN76|S6A14_HUMAN
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
Search

SLC6A14

0.51	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0006865	amino acid transport
0.55	GO:0055085	transmembrane transport
0.55	GO:0015837	amine transport
0.54	GO:0009636	response to toxic substance
0.49	GO:0006520	cellular amino acid metabolic process

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.50	GO:0005275	amine transmembrane transporter activity
0.50	GO:0015171	amino acid transmembrane transporter activity

0.66	GO:0031526	brush border membrane
0.54	GO:0070062	extracellular exosome
0.54	GO:0005887	integral component of plasma membrane

sp|Q9UN79|SOX13_HUMAN
Transcription factor SOX-13
Search

SOX13

0.97	Transcription factor SOX-13

0.64	GO:0045586	regulation of gamma-delta T cell differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.35	GO:0016070	RNA metabolic process
0.35	GO:0010467	gene expression
0.35	GO:0009653	anatomical structure morphogenesis
0.34	GO:0034654	nucleobase-containing compound biosynthetic process
0.34	GO:0009059	macromolecule biosynthetic process
0.33	GO:0044260	cellular macromolecule metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.34	GO:0043522	leucine zipper domain binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UN81|LORF1_HUMAN
LINE-1 retrotransposable element ORF1 protein
Search

0.23	Line-1 repeat mRNA with 2 open reading frames

0.82	GO:0032197	transposition, RNA-mediated
0.36	GO:0007411	axon guidance
0.35	GO:0030168	platelet activation
0.35	GO:0006278	RNA-dependent DNA biosynthetic process
0.33	GO:0051209	release of sequestered calcium ion into cytosol
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0000413	protein peptidyl-prolyl isomerization
0.32	GO:0006457	protein folding
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.75	GO:0003727	single-stranded RNA binding
0.36	GO:0140097	catalytic activity, acting on DNA
0.35	GO:0042802	identical protein binding
0.35	GO:0003697	single-stranded DNA binding
0.34	GO:0016779	nucleotidyltransferase activity
0.34	GO:0005507	copper ion binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.33	GO:0004497	monooxygenase activity
0.33	GO:1901265	nucleoside phosphate binding

0.58	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0005764	lysosome
0.35	GO:0005730	nucleolus
0.35	GO:0005783	endoplasmic reticulum
0.32	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016779

sp|Q9UN86|G3BP2_HUMAN
Ras GTPase-activating protein-binding protein 2
Search

G3BP2

0.91	Ras GTPase-activating protein-binding protein 2

0.85	GO:0034063	stress granule assembly
0.40	GO:0051028	mRNA transport
0.38	GO:0007264	small GTPase mediated signal transduction
0.38	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.37	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.58	GO:0003723	RNA binding
0.37	GO:0030159	receptor signaling complex scaffold activity
0.34	GO:0004386	helicase activity
0.34	GO:0004519	endonuclease activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005829	cytosol
0.37	GO:0010494	cytoplasmic stress granule
0.33	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane

sp|Q9UN88|GBRT_HUMAN
Gamma-aminobutyric acid receptor subunit theta
Search

GABRQ

0.97	Gamma-aminobutyric acid type A receptor theta subunit

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.42	GO:0006821	chloride transport
0.35	GO:0006457	protein folding
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0006836	neurotransmitter transport

0.83	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.42	GO:0005254	chloride channel activity
0.41	GO:0099095	ligand-gated anion channel activity
0.39	GO:0022835	transmitter-gated channel activity
0.35	GO:0051082	unfolded protein binding
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.33	GO:0005507	copper ion binding
0.32	GO:0005326	neurotransmitter transporter activity

0.55	GO:0005886	plasma membrane
0.55	GO:0043235	receptor complex
0.39	GO:0034707	chloride channel complex
0.38	GO:0098794	postsynapse
0.37	GO:0030054	cell junction

0.34

EC:1.14.17

GO:0016715

sp|Q9UNA0|ATS5_HUMAN
A disintegrin and metalloproteinase with thrombospondin motifs 5
Search

ADAMTS5

0.97	A disintegrin and metalloproteinase with thrombospondin motifs 5

0.62	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0006508	proteolysis
0.54	GO:0042742	defense response to bacterium
0.42	GO:0044691	tooth eruption
0.37	GO:0007507	heart development
0.37	GO:0001542	ovulation from ovarian follicle
0.37	GO:0060343	trabecula formation
0.37	GO:0061384	heart trabecula morphogenesis
0.37	GO:0030198	extracellular matrix organization
0.36	GO:0001822	kidney development

0.70	GO:0004222	metalloendopeptidase activity
0.57	GO:0050840	extracellular matrix binding
0.57	GO:0008201	heparin binding
0.55	GO:0008270	zinc ion binding
0.38	GO:0002020	protease binding
0.36	GO:0005178	integrin binding
0.33	GO:0005328	neurotransmitter:sodium symporter activity

0.63	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0005615	extracellular space
0.38	GO:0016607	nuclear speck
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0044420	extracellular matrix component
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.70

GO:0004222

sp|Q9UNA1|RHG26_HUMAN
Rho GTPase-activating protein 26
Search

ARHGAP26

0.87	Rho GTPase-activating protein 26

0.76	GO:0051056	regulation of small GTPase mediated signal transduction
0.76	GO:0043547	positive regulation of GTPase activity
0.74	GO:0030036	actin cytoskeleton organization
0.60	GO:0007165	signal transduction
0.37	GO:0007399	nervous system development

0.76	GO:0005096	GTPase activator activity
0.54	GO:0005543	phospholipid binding
0.37	GO:0005515	protein binding

0.41	GO:0005925	focal adhesion
0.39	GO:0005856	cytoskeleton
0.36	GO:0005829	cytosol
0.30	GO:0044425	membrane part

sp|Q9UNA3|A4GCT_HUMAN
Alpha-1,4-N-acetylglucosaminyltransferase
Search

A4GNT

0.97	Alpha-1,4-N-acetylglucosaminyltransferase

0.63	GO:0050680	negative regulation of epithelial cell proliferation
0.60	GO:0006493	protein O-linked glycosylation
0.35	GO:0001576	globoside biosynthetic process
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0007009	plasma membrane organization

0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0015643	toxic substance binding
0.34	GO:0003676	nucleic acid binding

0.37	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0016757

sp|Q9UNA4|POLI_HUMAN
DNA polymerase iota
Search

POLI

0.94	DNA polymerase iota

0.65	GO:0006281	DNA repair
0.38	GO:0071494	cellular response to UV-C
0.37	GO:0071897	DNA biosynthetic process
0.35	GO:0006260	DNA replication

0.72	GO:0003684	damaged DNA binding
0.37	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.53	GO:0016607	nuclear speck
0.52	GO:0036464	cytoplasmic ribonucleoprotein granule

0.37

EC:2.7.7.7

GO:0003887

sp|Q9UND3|NPIA1_HUMAN
Nuclear pore complex-interacting protein family member A1
Search

0.95	Nuclear pore complex-interacting protein A type

0.39	GO:0051028	mRNA transport
0.37	GO:0015031	protein transport

0.36

GO:0005515

protein binding

0.61	GO:0005654	nucleoplasm
0.40	GO:0031965	nuclear membrane
0.40	GO:0005643	nuclear pore
0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UNE0|EDAR_HUMAN
Tumor necrosis factor receptor superfamily member EDAR
Search

EDAR

0.96	Tumor necrosis factor receptor superfamily member EDAR

0.42	GO:0060605	tube lumen cavitation
0.42	GO:0042346	positive regulation of NF-kappaB import into nucleus
0.41	GO:0001942	hair follicle development
0.41	GO:0042475	odontogenesis of dentin-containing tooth
0.41	GO:0007435	salivary gland morphogenesis
0.41	GO:0046330	positive regulation of JNK cascade
0.41	GO:0043473	pigmentation
0.40	GO:0006915	apoptotic process
0.39	GO:0030154	cell differentiation
0.38	GO:0010628	positive regulation of gene expression

0.37	GO:0004872	receptor activity
0.35	GO:0004871	signal transducer activity
0.35	GO:0005515	protein binding

0.40	GO:0045177	apical part of cell
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9UNE2|RPH3L_HUMAN
Rab effector Noc2
Search

RPH3AL

0.97	LOW QUALITY PROTEIN: rab effector Noc2

0.77	GO:0017157	regulation of exocytosis
0.69	GO:0006886	intracellular protein transport
0.55	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.52	GO:0042593	glucose homeostasis
0.45	GO:0006887	exocytosis
0.42	GO:0050714	positive regulation of protein secretion
0.42	GO:0048489	synaptic vesicle transport
0.42	GO:0099504	synaptic vesicle cycle
0.42	GO:0099643	signal release from synapse
0.42	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.81	GO:0017137	Rab GTPase binding
0.53	GO:0046872	metal ion binding
0.49	GO:0005544	calcium-dependent phospholipid binding
0.40	GO:0030274	LIM domain binding
0.38	GO:0019905	syntaxin binding
0.38	GO:0030276	clathrin binding
0.35	GO:0008092	cytoskeletal protein binding

0.45	GO:0005622	intracellular
0.42	GO:0098793	presynapse
0.41	GO:0031982	vesicle
0.40	GO:0012505	endomembrane system
0.39	GO:0005886	plasma membrane
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle

sp|Q9UNE7|CHIP_HUMAN
E3 ubiquitin-protein ligase CHIP
Search

STUB1

0.92	STIP1 like proteiny and U box-containing protein 1

0.72	GO:0016567	protein ubiquitination
0.60	GO:0090035	positive regulation of chaperone-mediated protein complex assembly
0.59	GO:0030579	ubiquitin-dependent SMAD protein catabolic process
0.59	GO:0031943	regulation of glucocorticoid metabolic process
0.56	GO:0071218	cellular response to misfolded protein
0.56	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.56	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.55	GO:0032091	negative regulation of protein binding
0.55	GO:0030968	endoplasmic reticulum unfolded protein response
0.55	GO:0031398	positive regulation of protein ubiquitination

0.72	GO:0004842	ubiquitin-protein transferase activity
0.59	GO:0030911	TPR domain binding
0.57	GO:0051879	Hsp90 protein binding
0.57	GO:0030544	Hsp70 protein binding
0.57	GO:0051787	misfolded protein binding
0.56	GO:0046332	SMAD binding
0.53	GO:0001664	G-protein coupled receptor binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0019900	kinase binding
0.52	GO:0061659	ubiquitin-like protein ligase activity

0.57	GO:0042405	nuclear inclusion body
0.55	GO:0030018	Z disc
0.51	GO:0000151	ubiquitin ligase complex
0.49	GO:0012505	endomembrane system
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.42	GO:0031982	vesicle
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.38	GO:0043234	protein complex

0.44	EC:6	GO:0016874
0.72	KEGG:R03876	GO:0004842

sp|Q9UNF0|PACN2_HUMAN
Protein kinase C and casein kinase substrate in neurons protein 2
Search

PACSIN2

0.95	Protein kinase C and casein kinase substrate in neurons protein 2

0.85	GO:0097320	plasma membrane tubulation
0.85	GO:0070836	caveola assembly
0.73	GO:0030036	actin cytoskeleton organization
0.60	GO:0036010	protein localization to endosome
0.58	GO:0045806	negative regulation of endocytosis
0.57	GO:0072584	caveolin-mediated endocytosis
0.54	GO:0048858	cell projection morphogenesis
0.51	GO:0016310	phosphorylation
0.38	GO:0048666	neuron development
0.37	GO:0097435	supramolecular fiber organization

0.60	GO:0070300	phosphatidic acid binding
0.56	GO:0045296	cadherin binding
0.53	GO:0016301	kinase activity
0.53	GO:0042802	identical protein binding
0.50	GO:0008092	cytoskeletal protein binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0005215	transporter activity
0.33	GO:0046872	metal ion binding

0.59	GO:0055038	recycling endosome membrane
0.58	GO:0005901	caveola
0.56	GO:0016607	nuclear speck
0.52	GO:0005911	cell-cell junction
0.52	GO:0019898	extrinsic component of membrane
0.50	GO:0005829	cytosol
0.41	GO:0032587	ruffle membrane
0.40	GO:0005769	early endosome
0.39	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005856	cytoskeleton

sp|Q9UNF1|MAGD2_HUMAN
Melanoma-associated antigen D2
Search

MAGED2

0.96	LOW QUALITY PROTEIN: trophinin

0.71	GO:0070294	renal sodium ion absorption
0.66	GO:0007565	female pregnancy
0.63	GO:0032922	circadian regulation of gene expression
0.56	GO:0042981	regulation of apoptotic process
0.49	GO:0050680	negative regulation of epithelial cell proliferation
0.48	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.46	GO:0042752	regulation of circadian rhythm
0.46	GO:0030308	negative regulation of cell growth
0.46	GO:0043406	positive regulation of MAP kinase activity
0.45	GO:0043068	positive regulation of programmed cell death

0.45	GO:0003713	transcription coactivator activity
0.45	GO:0042802	identical protein binding
0.35	GO:0004705	JUN kinase activity

0.59	GO:0005730	nucleolus
0.56	GO:0005829	cytosol
0.43	GO:0000785	chromatin
0.40	GO:0043234	protein complex
0.39	GO:0031093	platelet alpha granule lumen
0.35	GO:0005576	extracellular region
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0004705

sp|Q9UNG2|TNF18_HUMAN
Tumor necrosis factor ligand superfamily member 18
Search

TNFSF18

0.97	Tumor necrosis factor ligand superfamily member 18

0.76	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.74	GO:0002687	positive regulation of leukocyte migration
0.67	GO:0045785	positive regulation of cell adhesion
0.64	GO:0002309	T cell proliferation involved in immune response
0.59	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.58	GO:0042129	regulation of T cell proliferation
0.53	GO:2000329	negative regulation of T-helper 17 cell lineage commitment
0.51	GO:2000508	regulation of dendritic cell chemotaxis
0.51	GO:0007267	cell-cell signaling
0.51	GO:0090073	positive regulation of protein homodimerization activity

0.65	GO:0042802	identical protein binding
0.59	GO:0032813	tumor necrosis factor receptor superfamily binding
0.41	GO:0005125	cytokine activity

0.54	GO:0009986	cell surface
0.40	GO:0005615	extracellular space
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9UNH5|CC14A_HUMAN
Dual specificity protein phosphatase CDC14A
Search

CDC14A

0.96	Cell division cycle 14Aa

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.54	GO:0051256	mitotic spindle midzone assembly
0.53	GO:0071850	mitotic cell cycle arrest
0.51	GO:0007096	regulation of exit from mitosis
0.51	GO:0060271	cilium assembly
0.45	GO:0051301	cell division

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.49	GO:0004722	protein serine/threonine phosphatase activity

0.63	GO:0005813	centrosome
0.60	GO:0016604	nuclear body
0.54	GO:0005829	cytosol
0.51	GO:0000922	spindle pole
0.50	GO:0072686	mitotic spindle

0.79

GO:0008138

sp|Q9UNH6|SNX7_HUMAN
Sorting nexin-7
Search

SNX7

0.97	Sorting nexin-7

0.46	GO:0016050	vesicle organization
0.44	GO:0006897	endocytosis
0.43	GO:0001889	liver development
0.42	GO:0043066	negative regulation of apoptotic process
0.42	GO:0006915	apoptotic process
0.36	GO:0015031	protein transport

0.76	GO:0035091	phosphatidylinositol binding
0.44	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process
0.34	GO:0005515	protein binding

0.45	GO:0005768	endosome
0.45	GO:0019898	extrinsic component of membrane
0.37	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|Q9UNH7|SNX6_HUMAN
Sorting nexin-6
Search

SNX6

0.75	Sorting nexin

0.69	GO:0006886	intracellular protein transport
0.45	GO:0016050	vesicle organization
0.42	GO:0006897	endocytosis
0.38	GO:0042147	retrograde transport, endosome to Golgi
0.38	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.38	GO:1903593	regulation of histamine secretion by mast cell
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0030042	actin filament depolymerization
0.35	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.35	GO:0016241	regulation of macroautophagy

0.76	GO:0035091	phosphatidylinositol binding
0.47	GO:0034713	type I transforming growth factor beta receptor binding
0.40	GO:0034452	dynactin binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0003779	actin binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0070003	threonine-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.32	GO:0046872	metal ion binding

0.48	GO:0005768	endosome
0.45	GO:0005764	lysosome
0.44	GO:0019898	extrinsic component of membrane
0.39	GO:0030904	retromer complex
0.37	GO:0044433	cytoplasmic vesicle part
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.34	GO:0015629	actin cytoskeleton

sp|Q9UNI1|CELA1_HUMAN
Chymotrypsin-like elastase family member 1
Search

CELA1

0.92	Pancreatic elastase

0.61	GO:0006508	proteolysis
0.58	GO:0060309	elastin catabolic process
0.57	GO:0061113	pancreas morphogenesis
0.55	GO:0031017	exocrine pancreas development
0.53	GO:0035264	multicellular organism growth
0.53	GO:0048771	tissue remodeling
0.53	GO:0045766	positive regulation of angiogenesis
0.51	GO:0006954	inflammatory response
0.51	GO:0009791	post-embryonic development
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0008483	transaminase activity
0.32	GO:0030170	pyridoxal phosphate binding

0.45	GO:0005615	extracellular space
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|Q9UNI6|DUS12_HUMAN
Dual specificity protein phosphatase 12
Search

DUSP12

0.92	Dual specificity protein phosphatase 12

0.68	GO:0006470	protein dephosphorylation
0.54	GO:0033133	positive regulation of glucokinase activity
0.35	GO:0000188	inactivation of MAPK activity
0.34	GO:0030968	endoplasmic reticulum unfolded protein response
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.32	GO:0007062	sister chromatid cohesion
0.32	GO:0000724	double-strand break repair via homologous recombination
0.32	GO:0016310	phosphorylation

0.74	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.55	GO:0004725	protein tyrosine phosphatase activity
0.48	GO:0008270	zinc ion binding
0.42	GO:0003676	nucleic acid binding
0.40	GO:0019900	kinase binding
0.35	GO:0033549	MAP kinase phosphatase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.32	GO:0016301	kinase activity

0.47	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.32	GO:0030915	Smc5-Smc6 complex
0.30	GO:0044425	membrane part

0.74

GO:0008138

sp|Q9UNK0|STX8_HUMAN
Syntaxin-8
Search

STX8

0.93	Putative syntaxin-8 protein kinase regulator

0.66	GO:0045022	early endosome to late endosome transport
0.64	GO:1903076	regulation of protein localization to plasma membrane
0.63	GO:0071346	cellular response to interferon-gamma
0.53	GO:0006906	vesicle fusion
0.52	GO:0065009	regulation of molecular function
0.51	GO:0048278	vesicle docking
0.47	GO:0006886	intracellular protein transport
0.42	GO:0008333	endosome to lysosome transport
0.34	GO:0016310	phosphorylation

0.67	GO:0019869	chloride channel inhibitor activity
0.66	GO:0000149	SNARE binding
0.60	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0005484	SNAP receptor activity
0.34	GO:0016301	kinase activity

0.62	GO:0045335	phagocytic vesicle
0.62	GO:0055037	recycling endosome
0.61	GO:0005770	late endosome
0.61	GO:0005769	early endosome
0.60	GO:0005802	trans-Golgi network
0.60	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005829	cytosol
0.53	GO:0031201	SNARE complex
0.41	GO:0005765	lysosomal membrane
0.40	GO:0010008	endosome membrane

sp|Q9UNK4|PA2GD_HUMAN
Group IID secretory phospholipase A2
Search

PLA2G2D

0.67	Group IID secretory phospholipase A2

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.55	GO:0042130	negative regulation of T cell proliferation
0.55	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.37	GO:0046486	glycerolipid metabolic process
0.37	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.35	GO:0097164	ammonium ion metabolic process
0.35	GO:0009405	pathogenesis
0.35	GO:0006954	inflammatory response

0.82	GO:0004623	phospholipase A2 activity
0.81	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.81	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.70	GO:0005509	calcium ion binding
0.53	GO:0043395	heparan sulfate proteoglycan binding
0.51	GO:0008201	heparin binding
0.36	GO:0005543	phospholipid binding
0.36	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0072556	other organism presynaptic membrane
0.34	GO:0030141	secretory granule
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.82

EC:3.1.1.4

GO:0004623

sp|Q9UNK9|ANGE1_HUMAN
Protein angel homolog 1
Search

ANGEL1

0.97	Angel homolog 1 (Drosophila)

0.45	GO:0070935	3'-UTR-mediated mRNA stabilization
0.43	GO:0045930	negative regulation of mitotic cell cycle

0.85	GO:0008190	eukaryotic initiation factor 4E binding
0.75	GO:0019904	protein domain specific binding
0.44	GO:0003730	mRNA 3'-UTR binding

0.80	GO:0005801	cis-Golgi network
0.77	GO:0048471	perinuclear region of cytoplasm
0.69	GO:0005783	endoplasmic reticulum
0.67	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UNL2|SSRG_HUMAN
Translocon-associated protein subunit gamma
Search

0.90	Translocon-associated protein subunit gamma

0.76

GO:0006614

SRP-dependent cotranslational protein targeting to membrane

0.45	GO:0005622	intracellular
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0044422	organelle part
0.35	GO:0043227	membrane-bounded organelle
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UNL4|ING4_HUMAN
Inhibitor of growth protein 4
Search

ING4

0.71	Inhibitor of growth protein 4

0.79	GO:0008285	negative regulation of cell proliferation
0.78	GO:0016573	histone acetylation
0.76	GO:0043065	positive regulation of apoptotic process
0.56	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.53	GO:0007050	cell cycle arrest
0.52	GO:0045926	negative regulation of growth
0.51	GO:0006915	apoptotic process
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0006260	DNA replication
0.42	GO:0002244	hematopoietic progenitor cell differentiation

0.81	GO:0140034	methylation-dependent protein binding
0.77	GO:0042393	histone binding
0.53	GO:0046872	metal ion binding
0.51	GO:0003713	transcription coactivator activity
0.33	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.55	GO:0031248	protein acetyltransferase complex
0.51	GO:0045111	intermediate filament cytoskeleton
0.50	GO:0043233	organelle lumen
0.46	GO:0005829	cytosol
0.45	GO:0044446	intracellular organelle part

sp|Q9UNM6|PSD13_HUMAN
26S proteasome non-ATPase regulatory subunit 13
Search

PSMD13

0.90	26S proteasome non-ATPase regulatory subunit 13

0.54	GO:0007127	meiosis I
0.49	GO:0043248	proteasome assembly
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.46	GO:0030097	hemopoiesis
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation

0.42	GO:0005198	structural molecule activity
0.33	GO:0004175	endopeptidase activity

0.70	GO:1905369	endopeptidase complex
0.57	GO:0043234	protein complex
0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

sp|Q9UNN4|TF2AY_HUMAN
TFIIA-alpha and beta-like factor
Search

GTF2A1L

0.96	General transcription factor IIA subunit 1 like

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.58	GO:0030100	regulation of endocytosis
0.54	GO:0006897	endocytosis
0.40	GO:2001141	regulation of RNA biosynthetic process
0.39	GO:0050890	cognition
0.36	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0006413	translational initiation
0.35	GO:0010468	regulation of gene expression
0.35	GO:0051254	positive regulation of RNA metabolic process

0.48	GO:0003713	transcription coactivator activity
0.37	GO:0001094	TFIID-class transcription factor binding
0.36	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.36	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.36	GO:0017025	TBP-class protein binding
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0003677	DNA binding

0.83	GO:0005672	transcription factor TFIIA complex
0.35	GO:0005737	cytoplasm
0.33	GO:0048475	coated membrane
0.33	GO:0098793	presynapse
0.32	GO:0098796	membrane protein complex

sp|Q9UNN5|FAF1_HUMAN
FAS-associated factor 1
Search

FAF1

0.44	Phosphoglycerate kinase

0.74	GO:0008219	cell death
0.60	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.59	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.54	GO:0031334	positive regulation of protein complex assembly
0.53	GO:0042176	regulation of protein catabolic process
0.52	GO:0030155	regulation of cell adhesion
0.46	GO:0060037	pharyngeal system development
0.45	GO:0051216	cartilage development
0.35	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0045859	regulation of protein kinase activity

0.59	GO:0051059	NF-kappaB binding
0.55	GO:0043130	ubiquitin binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0019901	protein kinase binding
0.53	GO:0031072	heat shock protein binding
0.53	GO:0019904	protein domain specific binding
0.35	GO:0019887	protein kinase regulator activity
0.35	GO:0004618	phosphoglycerate kinase activity
0.33	GO:0051082	unfolded protein binding
0.32	GO:0004674	protein serine/threonine kinase activity

0.58	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005635	nuclear envelope
0.49	GO:0005829	cytosol
0.36	GO:0031265	CD95 death-inducing signaling complex
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.2.3	GO:0004618
0.35	KEGG:R01512	GO:0004618

sp|Q9UNN8|EPCR_HUMAN
Endothelial protein C receptor
Search

PROCR

0.97	Endothelial cell protein C receptor

0.69	GO:0050819	negative regulation of coagulation
0.44	GO:0007596	blood coagulation
0.38	GO:0050900	leukocyte migration

0.65	GO:0004872	receptor activity
0.37	GO:0008022	protein C-terminus binding

0.63	GO:0005813	centrosome
0.40	GO:0005925	focal adhesion
0.40	GO:0070062	extracellular exosome
0.39	GO:0009986	cell surface
0.36	GO:0005887	integral component of plasma membrane

sp|Q9UNP4|SIAT9_HUMAN
Lactosylceramide alpha-2,3-sialyltransferase
Search

ST3GAL5

0.95	Lactosylceramide alpha-2,3-sialyltransferase

0.82	GO:0097503	sialylation
0.73	GO:0006486	protein glycosylation
0.47	GO:0018196	peptidyl-asparagine modification
0.43	GO:0009311	oligosaccharide metabolic process
0.39	GO:0006688	glycosphingolipid biosynthetic process
0.36	GO:0001573	ganglioside metabolic process
0.36	GO:0046513	ceramide biosynthetic process
0.32	GO:0006351	transcription, DNA-templated

0.82	GO:0008373	sialyltransferase activity
0.35	GO:0004308	exo-alpha-sialidase activity
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.68	GO:0005794	Golgi apparatus
0.43	GO:0098588	bounding membrane of organelle
0.42	GO:0031984	organelle subcompartment
0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus

0.82

EC:2.4.99

GO:0008373

sp|Q9UNP9|PPIE_HUMAN
Peptidyl-prolyl cis-trans isomerase E
Search

PPIE

0.90	Peptidyl-prolyl cis-trans isomerase E

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.51	GO:0045070	positive regulation of viral genome replication
0.46	GO:0008380	RNA splicing
0.45	GO:0006397	mRNA processing
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.58	GO:0003723	RNA binding
0.35	GO:0016018	cyclosporin A binding
0.33	GO:0005515	protein binding

0.50	GO:0071007	U2-type catalytic step 2 spliceosome
0.49	GO:0016607	nuclear speck
0.44	GO:0005829	cytosol
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.33	GO:0005576	extracellular region

0.72

GO:0003755

sp|Q9UNQ0|ABCG2_HUMAN
ATP-binding cassette sub-family G member 2
Search

ABCG2

0.90	Placenta-specific ATP-binding cassette transporter

0.53	GO:0055085	transmembrane transport
0.53	GO:0046415	urate metabolic process
0.49	GO:0033344	cholesterol efflux
0.43	GO:0015893	drug transport
0.39	GO:0097744	urate salt excretion
0.38	GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine
0.38	GO:0019389	glucuronoside metabolic process
0.38	GO:1904479	negative regulation of intestinal absorption
0.38	GO:0042908	xenobiotic transport
0.38	GO:0060136	embryonic process involved in female pregnancy

0.63	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0017127	cholesterol transporter activity
0.38	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0015238	drug transmembrane transporter activity
0.35	GO:0008092	cytoskeletal protein binding
0.35	GO:0015232	heme transporter activity

0.47	GO:0016324	apical plasma membrane
0.46	GO:0043235	receptor complex
0.44	GO:0005634	nucleus
0.37	GO:0031966	mitochondrial membrane
0.33	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.34

GO:0004721

sp|Q9UNQ2|DIM1_HUMAN
Probable dimethyladenosine transferase
Search

DIMT1

0.62	rRNA adenine N(6)-methyltransferase

0.71	GO:0031167	rRNA methylation
0.55	GO:2000234	positive regulation of rRNA processing
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.78	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity
0.59	GO:0003723	RNA binding
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity

0.48	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.44	GO:0005759	mitochondrial matrix

0.78

GO:0000179

sp|Q9UNS1|TIM_HUMAN
Protein timeless homolog
Search

TIMELESS

0.91	Timeless circadian regulator

0.86	GO:1904976	cellular response to bleomycin
0.86	GO:0072719	cellular response to cisplatin
0.85	GO:0072711	cellular response to hydroxyurea
0.85	GO:2000781	positive regulation of double-strand break repair
0.81	GO:0042752	regulation of circadian rhythm
0.80	GO:0048754	branching morphogenesis of an epithelial tube
0.80	GO:0030324	lung development
0.78	GO:0007623	circadian rhythm
0.78	GO:0044770	cell cycle phase transition
0.75	GO:0000122	negative regulation of transcription by RNA polymerase II

0.72	GO:0042803	protein homodimerization activity
0.71	GO:0046982	protein heterodimerization activity
0.36	GO:0016853	isomerase activity

0.72	GO:0000790	nuclear chromatin
0.38	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.36

EC:5

GO:0016853

sp|Q9UNS2|CSN3_HUMAN
COP9 signalosome complex subunit 3
Search

COPS3

0.89	COP9 constitutive photomorphogenic homolog subunit 3

0.57	GO:0000338	protein deneddylation
0.51	GO:0001701	in utero embryonic development
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0009416	response to light stimulus
0.33	GO:0065009	regulation of molecular function
0.33	GO:0007165	signal transduction

0.35	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator
0.30	GO:0003824	catalytic activity

0.77	GO:0008180	COP9 signalosome
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

sp|Q9UNT1|RBL2B_HUMAN
Rab-like protein 2B
Search

0.97	RAB, member of RAS oncogene family like 2A

0.45	GO:0008594	photoreceptor cell morphogenesis
0.43	GO:0060271	cilium assembly
0.43	GO:0030317	flagellated sperm motility
0.43	GO:0007338	single fertilization
0.43	GO:0006913	nucleocytoplasmic transport
0.39	GO:0042073	intraciliary transport

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.44	GO:0097225	sperm midpiece
0.43	GO:0030992	intraciliary transport particle B
0.40	GO:0000242	pericentriolar material
0.39	GO:0036064	ciliary basal body
0.39	GO:0005814	centriole
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UNU6|CP8B1_HUMAN
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
Search

CYP8B1

0.97	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase

0.53	GO:0046457	prostanoid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0006693	prostaglandin metabolic process
0.39	GO:0006699	bile acid biosynthetic process
0.37	GO:0016125	sterol metabolic process
0.36	GO:0006706	steroid catabolic process
0.36	GO:0071310	cellular response to organic substance
0.36	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.36	GO:0042981	regulation of apoptotic process
0.36	GO:0042632	cholesterol homeostasis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.55	GO:0008116	prostaglandin-I synthase activity
0.35	GO:0019825	oxygen binding

0.68	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.35	GO:0005901	caveola
0.33	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.68	EC:1.14	GO:0016705
0.55	KEGG:R02267	GO:0008116

sp|Q9UNW1|MINP1_HUMAN
Multiple inositol polyphosphate phosphatase 1
Search

MINPP1

0.92	Multiple inositol polyphosphate phosphatase 1

0.68	GO:0016311	dephosphorylation
0.38	GO:0030282	bone mineralization
0.37	GO:0043647	inositol phosphate metabolic process
0.37	GO:0006797	polyphosphate metabolic process
0.36	GO:0048015	phosphatidylinositol-mediated signaling
0.34	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0034417	bisphosphoglycerate 3-phosphatase activity
0.53	GO:0052745	inositol phosphate phosphatase activity
0.50	GO:0003993	acid phosphatase activity
0.37	GO:0101006	protein histidine phosphatase activity

0.44	GO:0005788	endoplasmic reticulum lumen
0.39	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.70	EC:3.1.3.80	GO:0034417
0.70	KEGG:R09532	GO:0034417

sp|Q9UNW8|GP132_HUMAN
Probable G-protein coupled receptor 132
Search

GPR132

0.97	G-protein-coupled receptor 4

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.63	GO:0000082	G1/S transition of mitotic cell cycle
0.50	GO:0009268	response to pH
0.48	GO:0072144	glomerular mesangial cell development
0.46	GO:0060055	angiogenesis involved in wound healing
0.45	GO:0016525	negative regulation of angiogenesis
0.39	GO:2001206	positive regulation of osteoclast development
0.39	GO:0023056	positive regulation of signaling
0.39	GO:0010647	positive regulation of cell communication

0.72

GO:0004930

G-protein coupled receptor activity

0.37

GO:0005887

integral component of plasma membrane

sp|Q9UNW9|NOVA2_HUMAN
RNA-binding protein Nova-2
Search

0.90	Neuro-oncological ventral antigen 2

0.75	GO:0000398	mRNA splicing, via spliceosome
0.37	GO:0051252	regulation of RNA metabolic process

0.59

GO:0003723

RNA binding

sp|Q9UNX3|RL26L_HUMAN
60S ribosomal protein L26-like 1
Search

RPL26

0.78	Ribosomal protein L26, pseudogene 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.55	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.54	GO:1904803	regulation of translation involved in cellular response to UV
0.54	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.54	GO:0010467	gene expression
0.53	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0042273	ribosomal large subunit biogenesis
0.52	GO:0071480	cellular response to gamma radiation

0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.71	GO:0015934	large ribosomal subunit
0.53	GO:0022626	cytosolic ribosome
0.46	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0043195	terminal bouton
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UNX4|WDR3_HUMAN
WD repeat-containing protein 3
Search

WDR3

0.95	WD repeat-containing protein 3

0.61

GO:0030490

maturation of SSU-rRNA

0.64

GO:0030515

snoRNA binding

0.77	GO:0031965	nuclear membrane
0.73	GO:0005730	nucleolus
0.63	GO:0030686	90S preribosome
0.62	GO:0032040	small-subunit processome
0.49	GO:0043234	protein complex
0.37	GO:0005654	nucleoplasm

sp|Q9UNX9|KCJ14_HUMAN
ATP-sensitive inward rectifier potassium channel 14
Search

KCNJ14

0.83	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.58	GO:0014861	regulation of skeletal muscle contraction via regulation of action potential
0.57	GO:0090076	relaxation of skeletal muscle
0.56	GO:0055119	relaxation of cardiac muscle
0.56	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.55	GO:0086002	cardiac muscle cell action potential involved in contraction
0.55	GO:0061337	cardiac conduction
0.54	GO:0051289	protein homotetramerization

0.84	GO:0005242	inward rectifier potassium channel activity
0.56	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.48	GO:0042802	identical protein binding
0.34	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.51	GO:0008076	voltage-gated potassium channel complex
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite
0.38	GO:0005790	smooth endoplasmic reticulum
0.38	GO:0030315	T-tubule
0.38	GO:0014704	intercalated disc
0.38	GO:0044309	neuron spine
0.37	GO:0005791	rough endoplasmic reticulum
0.37	GO:0098794	postsynapse
0.36	GO:0005794	Golgi apparatus

sp|Q9UNY4|TTF2_HUMAN
Transcription termination factor 2
Search

TTF2

0.94	Transcription termination factor, RNA polymerase II

0.37	GO:0006369	termination of RNA polymerase II transcription
0.37	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.55	GO:0008270	zinc ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004386	helicase activity
0.35	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.52	GO:0005829	cytosol
0.38	GO:0005681	spliceosomal complex
0.36	GO:0008023	transcription elongation factor complex

sp|Q9UNY5|ZN232_HUMAN
Zinc finger protein 232
Search

0.92	Zinc finger and SCAN domain-containing protein 11

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.44	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.39	GO:0015074	DNA integration
0.33	GO:0051253	negative regulation of RNA metabolic process
0.33	GO:0010558	negative regulation of macromolecule biosynthetic process

0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.36	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0015630	microtubule cytoskeleton
0.36	GO:0044446	intracellular organelle part
0.35	GO:0097197	tetraspanin-enriched microdomain
0.35	GO:0001772	immunological synapse
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9UNZ2|NSF1C_HUMAN
NSFL1 cofactor p47
Search

NSFL1C

0.97	NSFL1 cofactor

0.67	GO:0031468	nuclear envelope reassembly
0.64	GO:0000045	autophagosome assembly
0.64	GO:0007030	Golgi organization
0.61	GO:0043666	regulation of phosphoprotein phosphatase activity
0.60	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.55	GO:0061025	membrane fusion

0.63	GO:0043130	ubiquitin binding
0.62	GO:0019888	protein phosphatase regulator activity
0.49	GO:0008289	lipid binding
0.48	GO:0051117	ATPase binding
0.37	GO:0043168	anion binding

0.77	GO:0045111	intermediate filament cytoskeleton
0.69	GO:0005829	cytosol
0.68	GO:0005654	nucleoplasm
0.55	GO:0005886	plasma membrane
0.52	GO:0005795	Golgi stack
0.51	GO:1990730	VCP-NSFL1C complex
0.46	GO:0005694	chromosome

sp|Q9UNZ5|L10K_HUMAN
Leydig cell tumor 10 kDa protein homolog
Search

0.97	LOW QUALITY PROTEIN: leydig cell tumor 10 kDa protein homolog

0.73

GO:0005730

nucleolus

sp|Q9UP38|FZD1_HUMAN
Frizzled-1
Search

FZD1

0.90	Frizzled class receptor 1

0.77	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.58	GO:0060022	hard palate development
0.58	GO:0045995	regulation of embryonic development
0.58	GO:0035412	regulation of catenin import into nucleus
0.58	GO:0060429	epithelium development
0.57	GO:1905276	regulation of epithelial tube formation
0.56	GO:0090175	regulation of establishment of planar polarity
0.56	GO:0035425	autocrine signaling
0.55	GO:0072497	mesenchymal stem cell differentiation

0.85	GO:0042813	Wnt-activated receptor activity
0.60	GO:0030165	PDZ domain binding
0.60	GO:0017147	Wnt-protein binding
0.58	GO:0005109	frizzled binding
0.46	GO:0004930	G-protein coupled receptor activity
0.46	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0045545	syndecan binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0004672	protein kinase activity

0.48	GO:0009986	cell surface
0.46	GO:0055038	recycling endosome membrane
0.42	GO:0005886	plasma membrane
0.36	GO:0005925	focal adhesion
0.36	GO:1990909	Wnt signalosome
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

sp|Q9UP52|TFR2_HUMAN
Transferrin receptor protein 2
Search

TFR2

0.91	Transferrin receptor

0.85	GO:0033572	transferrin transport
0.66	GO:0055072	iron ion homeostasis
0.64	GO:0097286	iron ion import
0.63	GO:0006898	receptor-mediated endocytosis
0.59	GO:1903319	positive regulation of protein maturation
0.59	GO:0071281	cellular response to iron ion
0.58	GO:0098659	inorganic cation import across plasma membrane
0.58	GO:0046916	cellular transition metal ion homeostasis
0.58	GO:0090277	positive regulation of peptide hormone secretion
0.58	GO:0045807	positive regulation of endocytosis

0.85	GO:0033570	transferrin transmembrane transporter activity
0.78	GO:0004998	transferrin receptor activity
0.61	GO:0039706	co-receptor binding
0.43	GO:0003725	double-stranded RNA binding
0.43	GO:0042803	protein homodimerization activity
0.38	GO:0005128	erythropoietin receptor binding
0.36	GO:0005179	hormone activity
0.34	GO:0001618	virus receptor activity
0.34	GO:0030544	Hsp70 protein binding
0.33	GO:0051087	chaperone binding

0.65	GO:1990712	HFE-transferrin receptor complex
0.60	GO:0009897	external side of plasma membrane
0.55	GO:0031410	cytoplasmic vesicle
0.51	GO:0005887	integral component of plasma membrane
0.45	GO:0016323	basolateral plasma membrane
0.45	GO:0005905	clathrin-coated pit
0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0070062	extracellular exosome
0.42	GO:0098588	bounding membrane of organelle
0.38	GO:0044446	intracellular organelle part

sp|Q9UP65|PA24C_HUMAN
Cytosolic phospholipase A2 gamma
Search

PLA2G4C

0.86	Cytosolic phospholipase A2 gamma

0.80	GO:0009395	phospholipid catabolic process
0.52	GO:0046503	glycerolipid catabolic process
0.50	GO:0006690	icosanoid metabolic process
0.50	GO:0071236	cellular response to antibiotic
0.49	GO:0033559	unsaturated fatty acid metabolic process
0.48	GO:1901570	fatty acid derivative biosynthetic process
0.47	GO:0006650	glycerophospholipid metabolic process
0.47	GO:0050482	arachidonic acid secretion
0.45	GO:0071407	cellular response to organic cyclic compound
0.43	GO:0006633	fatty acid biosynthetic process

0.76	GO:0004620	phospholipase activity
0.63	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.63	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.43	GO:0046872	metal ion binding
0.38	GO:0005543	phospholipid binding
0.33	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity

0.48	GO:0032587	ruffle membrane
0.47	GO:0005938	cell cortex
0.47	GO:0005635	nuclear envelope
0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.44	GO:0031982	vesicle
0.38	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005819	spindle
0.35	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:3.1.1

GO:0004620

sp|Q9UP79|ATS8_HUMAN
A disintegrin and metalloproteinase with thrombospondin motifs 8
Search

ADAMTS8

0.96	A disintegrin and metalloproteinase with thrombospondin motifs 8

0.60	GO:0006508	proteolysis
0.58	GO:0007229	integrin-mediated signaling pathway
0.45	GO:0001542	ovulation from ovarian follicle
0.44	GO:0060347	heart trabecula formation
0.43	GO:0001822	kidney development
0.35	GO:0008285	negative regulation of cell proliferation
0.35	GO:0035435	phosphate ion transmembrane transport
0.35	GO:0044691	tooth eruption
0.35	GO:2000026	regulation of multicellular organismal development
0.35	GO:0071374	cellular response to parathyroid hormone stimulus

0.69	GO:0004222	metalloendopeptidase activity
0.62	GO:0008270	zinc ion binding
0.45	GO:0008201	heparin binding
0.37	GO:0009673	low-affinity phosphate transmembrane transporter activity
0.36	GO:0005178	integrin binding

0.74	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0044420	extracellular matrix component
0.40	GO:0031410	cytoplasmic vesicle

0.69

GO:0004222

sp|Q9UP83|COG5_HUMAN
Conserved oligomeric Golgi complex subunit 5
Search

COG5

0.92	Component of oligomeric golgi complex 5

0.79	GO:0006891	intra-Golgi vesicle-mediated transport
0.36	GO:0006888	ER to Golgi vesicle-mediated transport
0.35	GO:0015031	protein transport

0.34

GO:0005515

protein binding

0.78	GO:0017119	Golgi transport complex
0.49	GO:0005654	nucleoplasm
0.36	GO:0032588	trans-Golgi network membrane
0.36	GO:0005829	cytosol

sp|Q9UP95|S12A4_HUMAN
Solute carrier family 12 member 4
Search

SLC12A4

0.96	Potassium-chloride cotransporter-1

0.77	GO:1902476	chloride transmembrane transport
0.68	GO:0071477	cellular hypotonic salinity response
0.46	GO:0007268	chemical synaptic transmission
0.44	GO:0071805	potassium ion transmembrane transport
0.35	GO:0006884	cell volume homeostasis
0.34	GO:0006508	proteolysis
0.34	GO:0034975	protein folding in endoplasmic reticulum
0.33	GO:0006879	cellular iron ion homeostasis
0.32	GO:0006629	lipid metabolic process

0.85	GO:0015379	potassium:chloride symporter activity
0.51	GO:0019901	protein kinase binding
0.47	GO:0022820	potassium ion symporter activity
0.37	GO:0008239	dipeptidyl-peptidase activity
0.37	GO:0016805	dipeptidase activity
0.36	GO:0008235	metalloexopeptidase activity
0.33	GO:0008374	O-acyltransferase activity
0.33	GO:0008199	ferric iron binding

0.54	GO:0005887	integral component of plasma membrane
0.37	GO:0005765	lysosomal membrane
0.34	GO:0072546	ER membrane protein complex

0.37

EC:3.4.13

GO:0016805

sp|Q9UPA5|BSN_HUMAN
Protein bassoon
Search

BSN

0.97	Bassoon presynaptic cytomatrix protein

0.85	GO:0007416	synapse assembly
0.72	GO:0099526	presynapse to nucleus signaling pathway
0.68	GO:0035418	protein localization to synapse
0.40	GO:0048790	maintenance of presynaptic active zone structure
0.39	GO:0008090	retrograde axonal transport
0.38	GO:0007268	chemical synaptic transmission
0.37	GO:0007010	cytoskeleton organization
0.35	GO:0006508	proteolysis
0.32	GO:0030073	insulin secretion
0.32	GO:0019933	cAMP-mediated signaling

0.52	GO:0046872	metal ion binding
0.41	GO:0098882	structural constituent of presynaptic active zone
0.40	GO:0001222	transcription corepressor binding
0.39	GO:0045503	dynein light chain binding
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0005522	profilin binding

0.83	GO:0048786	presynaptic active zone
0.65	GO:0044306	neuron projection terminus
0.64	GO:0014069	postsynaptic density
0.64	GO:0099738	cell cortex region
0.62	GO:0030425	dendrite
0.62	GO:0030424	axon
0.59	GO:0009986	cell surface
0.46	GO:0060076	excitatory synapse
0.44	GO:0099569	presynaptic cytoskeleton
0.42	GO:0030054	cell junction

sp|Q9UPC5|GPR34_HUMAN
Probable G-protein coupled receptor 34
Search

GPR34

0.78	G-protein-coupled receptor GPR34 type 1

0.71

GO:0007186

G-protein coupled receptor signaling pathway

0.72

GO:0004930

G-protein coupled receptor activity

0.38

GO:0005887

integral component of plasma membrane

sp|Q9UPE1|SRPK3_HUMAN
SRSF protein kinase 3
Search

SRPK3

0.87	Serine/arginine-rich protein specific kinase 3

0.63	GO:0006468	protein phosphorylation
0.60	GO:0007519	skeletal muscle tissue development
0.49	GO:0000245	spliceosomal complex assembly
0.47	GO:0050684	regulation of mRNA processing
0.43	GO:0007165	signal transduction
0.38	GO:0030154	cell differentiation
0.34	GO:0015910	peroxisomal long-chain fatty acid import
0.34	GO:0055085	transmembrane transport

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0017154	semaphorin receptor activity
0.35	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.34	GO:0005324	long-chain fatty acid transporter activity
0.34	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9UPG8|PLAL2_HUMAN
Zinc finger protein PLAGL2
Search

PLAGL2

0.96	Zinc finger protein PLAGL2

0.49	GO:0034378	chylomicron assembly
0.46	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.46	GO:1903955	positive regulation of protein targeting to mitochondrion
0.44	GO:0009791	post-embryonic development
0.43	GO:0006366	transcription by RNA polymerase II
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0006629	lipid metabolic process
0.37	GO:0006915	apoptotic process

0.51	GO:0003676	nucleic acid binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0046872	metal ion binding

0.39

GO:0005634

nucleus

sp|Q9UPI3|FLVC2_HUMAN
Feline leukemia virus subgroup C receptor-related protein 2
Search

FLVCR2

0.95	Feline leukemia virus subgroup C receptor 2

0.54	GO:0015886	heme transport
0.53	GO:0055085	transmembrane transport
0.38	GO:0048536	spleen development
0.38	GO:0060323	head morphogenesis
0.37	GO:0042733	embryonic digit morphogenesis
0.37	GO:0035264	multicellular organism growth
0.37	GO:0030218	erythrocyte differentiation
0.37	GO:0046620	regulation of organ growth
0.37	GO:0048704	embryonic skeletal system morphogenesis
0.37	GO:0001568	blood vessel development

0.54	GO:0015232	heme transporter activity
0.46	GO:0020037	heme binding

0.35	GO:0005886	plasma membrane
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|Q9UPM6|LHX6_HUMAN
LIM/homeobox protein Lhx6
Search

LHX6

0.97	LIM homeobox 6

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.44	GO:0021884	forebrain neuron development
0.41	GO:0042475	odontogenesis of dentin-containing tooth
0.41	GO:0008585	female gonad development
0.40	GO:0007611	learning or memory
0.39	GO:1904936	interneuron migration
0.39	GO:0021830	interneuron migration from the subpallium to the cortex
0.39	GO:0021800	cerebral cortex tangential migration

0.62	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.36	GO:0005882	intermediate filament

sp|Q9UPM8|AP4E1_HUMAN
AP-4 complex subunit epsilon-1
Search

AP4E1

0.97	AP-4 complex subunit epsilon-1

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport

0.35

GO:0005515

protein binding

0.85	GO:0030124	AP-4 adaptor complex
0.38	GO:0005802	trans-Golgi network
0.38	GO:0031904	endosome lumen
0.35	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

sp|Q9UPM9|B9D1_HUMAN
B9 domain-containing protein 1
Search

B9D1

0.96	B9 domain-containing protein 1

0.84	GO:0060563	neuroepithelial cell differentiation
0.84	GO:0042733	embryonic digit morphogenesis
0.84	GO:0007224	smoothened signaling pathway
0.80	GO:0060271	cilium assembly
0.79	GO:0043010	camera-type eye development
0.78	GO:0001944	vasculature development
0.76	GO:0001701	in utero embryonic development
0.73	GO:0032880	regulation of protein localization
0.40	GO:0140056	organelle localization by membrane tethering

0.86	GO:0008158	hedgehog receptor activity
0.37	GO:0005515	protein binding

0.85	GO:0036038	MKS complex
0.82	GO:0036064	ciliary basal body
0.78	GO:0005813	centrosome
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9UPN3|MACF1_HUMAN
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5
Search

MACF1

0.60	Microtubule-actin crosslinking factor 1

0.57	GO:0045773	positive regulation of axon extension
0.56	GO:0090109	regulation of cell-substrate junction assembly
0.56	GO:1903391	regulation of adherens junction organization
0.56	GO:0043001	Golgi to plasma membrane protein transport
0.56	GO:0001952	regulation of cell-matrix adhesion
0.53	GO:0032886	regulation of microtubule-based process
0.53	GO:0030334	regulation of cell migration
0.47	GO:0060832	oocyte animal/vegetal axis specification

0.73	GO:0008017	microtubule binding
0.69	GO:0005509	calcium ion binding
0.68	GO:0003779	actin binding
0.54	GO:0045296	cadherin binding
0.51	GO:0032403	protein complex binding

0.56	GO:0032587	ruffle membrane
0.55	GO:0005856	cytoskeleton
0.50	GO:0099512	supramolecular fiber
0.49	GO:0005794	Golgi apparatus
0.43	GO:0044446	intracellular organelle part

sp|Q9UPN4|CP131_HUMAN
Centrosomal protein of 131 kDa
Search

CEP131

0.80	5-azacytidine-induced protein 1

0.86	GO:0035735	intraciliary transport involved in cilium assembly
0.48	GO:0071539	protein localization to centrosome
0.47	GO:0010824	regulation of centrosome duplication
0.47	GO:0090316	positive regulation of intracellular protein transport
0.45	GO:0008284	positive regulation of cell proliferation
0.43	GO:1905198	manchette assembly
0.43	GO:1990953	intramanchette transport
0.41	GO:0007288	sperm axoneme assembly
0.40	GO:1905515	non-motile cilium assembly

0.44	GO:0042803	protein homodimerization activity
0.44	GO:0032403	protein complex binding

0.77	GO:0005929	cilium
0.48	GO:0034451	centriolar satellite
0.47	GO:0045171	intercellular bridge
0.44	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0002177	manchette
0.40	GO:0001669	acrosomal vesicle
0.38	GO:0043231	intracellular membrane-bounded organelle

sp|Q9UPN6|SCAF8_HUMAN
Protein SCAF8
Search

SCAF8

0.92	SR-related CTD-associated factor 8

0.59

GO:0003723

RNA binding

0.59

GO:0005654

nucleoplasm

sp|Q9UPN7|PP6R1_HUMAN
Serine/threonine-protein phosphatase 6 regulatory subunit 1
Search

PPP6R1

0.91	LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 6 regulatory subunit 1

0.77	GO:0043666	regulation of phosphoprotein phosphatase activity
0.44	GO:0048208	COPII vesicle coating
0.37	GO:0010469	regulation of receptor activity

0.82	GO:0019903	protein phosphatase binding
0.68	GO:0017048	Rho GTPase binding
0.38	GO:0005179	hormone activity

0.66	GO:0005829	cytosol
0.50	GO:0005654	nucleoplasm
0.43	GO:0005886	plasma membrane
0.41	GO:0000139	Golgi membrane
0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UPN9|TRI33_HUMAN
E3 ubiquitin-protein ligase TRIM33
Search

TRIM33

0.86	Tripartite motif containing 33

0.71	GO:0030514	negative regulation of BMP signaling pathway
0.70	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.62	GO:0016567	protein ubiquitination
0.36	GO:0070562	regulation of vitamin D receptor signaling pathway
0.35	GO:0071391	cellular response to estrogen stimulus
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0046777	protein autophosphorylation
0.35	GO:0055074	calcium ion homeostasis
0.35	GO:0008285	negative regulation of cell proliferation
0.35	GO:0031647	regulation of protein stability

0.75	GO:0070410	co-SMAD binding
0.74	GO:0070412	R-SMAD binding
0.62	GO:0008270	zinc ion binding
0.36	GO:0034056	estrogen response element binding
0.35	GO:0016922	ligand-dependent nuclear receptor binding
0.35	GO:0002039	p53 binding
0.35	GO:0070577	lysine-acetylated histone binding
0.35	GO:0003713	transcription coactivator activity
0.34	GO:0003682	chromatin binding
0.34	GO:0061630	ubiquitin protein ligase activity

0.53	GO:0005634	nucleus
0.35	GO:0000791	euchromatin
0.34	GO:0031974	membrane-enclosed lumen
0.32	GO:0005737	cytoplasm

sp|Q9UPP1|PHF8_HUMAN
Histone lysine demethylase PHF8
Search

PHF8

0.85	PHD finger protein 8

0.71	GO:0035574	histone H4-K20 demethylation
0.69	GO:0061188	negative regulation of chromatin silencing at rDNA
0.68	GO:0033169	histone H3-K9 demethylation
0.68	GO:0070544	histone H3-K36 demethylation
0.66	GO:0071557	histone H3-K27 demethylation
0.66	GO:0045943	positive regulation of transcription by RNA polymerase I
0.64	GO:0000082	G1/S transition of mitotic cell cycle
0.50	GO:0060319	primitive erythrocyte differentiation
0.49	GO:0048703	embryonic viscerocranium morphogenesis
0.48	GO:0043523	regulation of neuron apoptotic process

0.71	GO:0035575	histone demethylase activity (H4-K20 specific)
0.68	GO:0032454	histone demethylase activity (H3-K9 specific)
0.68	GO:0051864	histone demethylase activity (H3-K36 specific)
0.66	GO:0071558	histone demethylase activity (H3-K27 specific)
0.65	GO:0035064	methylated histone binding
0.60	GO:0003682	chromatin binding
0.54	GO:0046872	metal ion binding
0.35	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.54	GO:0031974	membrane-enclosed lumen
0.53	GO:0012505	endomembrane system
0.49	GO:0031967	organelle envelope
0.49	GO:0031090	organelle membrane
0.49	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0043234	protein complex

0.68

EC:1.14.11.27

GO:0051864

sp|Q9UPP2|IQEC3_HUMAN
IQ motif and SEC7 domain-containing protein 3
Search

IQSEC3

0.97	IQ motif and SEC7 domain-containing protein 3

0.80	GO:0032012	regulation of ARF protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.44	GO:0030036	actin cytoskeleton organization

0.80

GO:0005086

ARF guanyl-nucleotide exchange factor activity

0.56	GO:0060077	inhibitory synapse
0.51	GO:0045211	postsynaptic membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UPP5|K1107_HUMAN
Uncharacterized protein KIAA1107
Search

0.86	BTB (POZ) domain containing 8

0.30

GO:0003824

catalytic activity

0.61

GO:0005654

nucleoplasm

sp|Q9UPQ0|LIMC1_HUMAN
LIM and calponin homology domains-containing protein 1
Search

LIMCH1

0.93	LIM and calponin like proteiny domains-containing protein 1

0.60

GO:0031032

actomyosin structure organization

0.55	GO:0003779	actin binding
0.54	GO:0046872	metal ion binding

sp|Q9UPQ3|AGAP1_HUMAN
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
Search

AGAP1

0.89	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

0.74	GO:0043547	positive regulation of GTPase activity
0.46	GO:0007165	signal transduction
0.37	GO:0015031	protein transport

0.75	GO:0005096	GTPase activator activity
0.65	GO:0003924	GTPase activity
0.63	GO:0032550	purine ribonucleoside binding
0.63	GO:0019001	guanyl nucleotide binding
0.52	GO:0032553	ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046872	metal ion binding
0.40	GO:0005543	phospholipid binding

0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q9UPQ4|TRI35_HUMAN
Tripartite motif-containing protein 35
Search

TRIM35

0.87	Tripartite motif-containing protein 35

0.66	GO:1902187	negative regulation of viral release from host cell
0.61	GO:0045087	innate immune response
0.60	GO:0043065	positive regulation of apoptotic process
0.60	GO:0045930	negative regulation of mitotic cell cycle
0.41	GO:0006915	apoptotic process
0.39	GO:0016567	protein ubiquitination
0.39	GO:0046597	negative regulation of viral entry into host cell
0.38	GO:0030218	erythrocyte differentiation
0.38	GO:0008285	negative regulation of cell proliferation
0.37	GO:0070206	protein trimerization

0.62	GO:0008270	zinc ion binding
0.39	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0005515	protein binding
0.32	GO:0016874	ligase activity
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding
0.31	GO:0043565	sequence-specific DNA binding

0.45	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.32	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.32	EC:6	GO:0016874
0.39	KEGG:R03876	GO:0004842

sp|Q9UPQ7|PZRN3_HUMAN
E3 ubiquitin-protein ligase PDZRN3
Search

PDZRN3

0.91	PDZ domain-containing RING finger protein 3

0.74	GO:0007528	neuromuscular junction development
0.67	GO:0016567	protein ubiquitination

0.67	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0061659	ubiquitin-like protein ligase activity
0.48	GO:0008270	zinc ion binding

0.74	GO:0031594	neuromuscular junction
0.60	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol

0.67

GO:0004842

sp|Q9UPQ8|DOLK_HUMAN
Dolichol kinase
Search

DOLK

0.81	Dolichol kinase

0.85	GO:0043048	dolichyl monophosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.45	GO:0006486	protein glycosylation
0.36	GO:0006489	dolichyl diphosphate biosynthetic process

0.85	GO:0004168	dolichol kinase activity
0.34	GO:0005515	protein binding

0.55

GO:0030176

integral component of endoplasmic reticulum membrane

0.85

EC:2.7.1.108

GO:0004168

sp|Q9UPQ9|TNR6B_HUMAN
Trinucleotide repeat-containing gene 6B protein
Search

TNRC6B

0.82	Trinucleotide repeat containing 6B

0.85	GO:0035278	miRNA mediated inhibition of translation
0.56	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.40	GO:0007223	Wnt signaling pathway, calcium modulating pathway
0.40	GO:0045652	regulation of megakaryocyte differentiation
0.32	GO:0009152	purine ribonucleotide biosynthetic process

0.49	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.32	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

0.38	GO:0000932	P-body
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.32	EC:4.3.2.2	GO:0004018
0.32	KEGG:R01083	GO:0004018

sp|Q9UPR0|PLCL2_HUMAN
Inactive phospholipase C-like protein 2
Search

PLCL2

0.53	Phosphoinositide phospholipase C

0.84	GO:0032228	regulation of synaptic transmission, GABAergic
0.72	GO:0016042	lipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.58	GO:0002337	B-1a B cell differentiation
0.57	GO:0050859	negative regulation of B cell receptor signaling pathway
0.57	GO:0002322	B cell proliferation involved in immune response
0.57	GO:1900122	positive regulation of receptor binding
0.54	GO:0007214	gamma-aminobutyric acid signaling pathway
0.54	GO:0033135	regulation of peptidyl-serine phosphorylation

0.85	GO:0050811	GABA receptor binding
0.83	GO:0070679	inositol 1,4,5 trisphosphate binding
0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.63	GO:0004871	signal transducer activity
0.41	GO:0005509	calcium ion binding

0.45	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

sp|Q9UPR3|SMG5_HUMAN
Protein SMG5
Search

SMG5

0.91	Smg-5 homolog, nonsense mediated mRNA decay factor

0.77	GO:0032204	regulation of telomere maintenance
0.71	GO:0035303	regulation of dephosphorylation
0.60	GO:0007004	telomere maintenance via telomerase
0.58	GO:0043487	regulation of RNA stability
0.58	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.56	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.54	GO:0051028	mRNA transport
0.54	GO:0006405	RNA export from nucleus
0.52	GO:0043009	chordate embryonic development
0.51	GO:0090501	RNA phosphodiester bond hydrolysis

0.81	GO:0070182	DNA polymerase binding
0.80	GO:0051721	protein phosphatase 2A binding
0.78	GO:0042162	telomeric DNA binding
0.77	GO:0042826	histone deacetylase binding
0.72	GO:0031625	ubiquitin protein ligase binding
0.61	GO:0070034	telomerase RNA binding
0.53	GO:0043021	ribonucleoprotein complex binding
0.51	GO:0004540	ribonuclease activity

0.60	GO:0005697	telomerase holoenzyme complex
0.47	GO:0005737	cytoplasm

sp|Q9UPR5|NAC2_HUMAN
Sodium/calcium exchanger 2
Search

SLC8A3

0.87	Solute carrier family 8 (sodium/calcium exchanger), member 3

0.77	GO:0035725	sodium ion transmembrane transport
0.77	GO:0006816	calcium ion transport
0.60	GO:0007154	cell communication
0.58	GO:0060291	long-term synaptic potentiation
0.57	GO:0007613	memory
0.57	GO:0007612	learning
0.56	GO:0006874	cellular calcium ion homeostasis
0.52	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.51	GO:0014819	regulation of skeletal muscle contraction
0.49	GO:0048709	oligodendrocyte differentiation

0.85	GO:0005432	calcium:sodium antiporter activity
0.53	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential

0.49	GO:0031594	neuromuscular junction
0.49	GO:0031226	intrinsic component of plasma membrane
0.49	GO:0042383	sarcolemma
0.48	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005741	mitochondrial outer membrane
0.44	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|Q9UPR6|ZFR2_HUMAN
Zinc finger RNA-binding protein 2
Search

ZFR2

0.70	Zinc finger RNA-binding protein 2

0.41	GO:0006955	immune response
0.33	GO:0007275	multicellular organism development

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016740	transferase activity

0.32	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

0.36

GO:0016740

sp|Q9UPS6|SET1B_HUMAN
Histone-lysine N-methyltransferase SETD1B
Search

SETD1B

0.81	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1B

0.83	GO:0051568	histone H3-K4 methylation
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:1902275	regulation of chromatin organization
0.35	GO:0002244	hematopoietic progenitor cell differentiation

0.80	GO:0018024	histone-lysine N-methyltransferase activity
0.56	GO:0003723	RNA binding
0.35	GO:0008013	beta-catenin binding
0.34	GO:0008134	transcription factor binding

0.81	GO:0048188	Set1C/COMPASS complex
0.48	GO:0005829	cytosol
0.41	GO:0016607	nuclear speck
0.39	GO:0005694	chromosome

0.80

GO:0018024

sp|Q9UPS8|ANR26_HUMAN
Ankyrin repeat domain-containing protein 26
Search

ANKRD26

0.88	Ankyrin repeat domain-containing protein 26

0.72	GO:0045599	negative regulation of fat cell differentiation
0.56	GO:0040015	negative regulation of multicellular organism growth
0.55	GO:0060259	regulation of feeding behavior
0.55	GO:0046621	negative regulation of organ growth
0.55	GO:0046627	negative regulation of insulin receptor signaling pathway
0.54	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:0019217	regulation of fatty acid metabolic process
0.52	GO:0042593	glucose homeostasis

0.51

GO:0005515

protein binding

0.77	GO:0005813	centrosome
0.53	GO:0005884	actin filament
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UPT5|EXOC7_HUMAN
Exocyst complex component 7
Search

EXOC7

0.67	Exocyst complex component 7

0.77	GO:0006887	exocytosis
0.59	GO:2000535	regulation of entry of bacterium into host cell
0.36	GO:0016241	regulation of macroautophagy
0.36	GO:0015031	protein transport

0.35

GO:0005515

protein binding

0.78	GO:0000145	exocyst
0.58	GO:0032584	growth cone membrane
0.57	GO:0034451	centriolar satellite
0.39	GO:0090543	Flemming body
0.36	GO:0005829	cytosol
0.35	GO:0097546	ciliary base
0.34	GO:0097731	9+0 non-motile cilium

sp|Q9UPT6|JIP3_HUMAN
C-Jun-amino-terminal kinase-interacting protein 3
Search

MAPK8IP3

0.92	C-Jun-amino-terminal kinase-interacting protein 3

0.57	GO:0016310	phosphorylation
0.47	GO:0043507	positive regulation of JUN kinase activity
0.46	GO:0000187	activation of MAPK activity
0.46	GO:0031098	stress-activated protein kinase signaling cascade
0.45	GO:0007585	respiratory gaseous exchange
0.45	GO:0048286	lung alveolus development
0.45	GO:0060425	lung morphogenesis
0.44	GO:0001701	in utero embryonic development
0.44	GO:0030900	forebrain development
0.43	GO:0007411	axon guidance

0.59	GO:0016301	kinase activity
0.48	GO:0008432	JUN kinase binding
0.48	GO:0005078	MAP-kinase scaffold activity
0.46	GO:0019894	kinesin binding
0.46	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.46	GO:0031434	mitogen-activated protein kinase kinase binding
0.43	GO:0030159	receptor signaling complex scaffold activity

0.45	GO:0005790	smooth endoplasmic reticulum
0.45	GO:0030673	axolemma
0.43	GO:0030425	dendrite
0.43	GO:0000139	Golgi membrane
0.37	GO:0030426	growth cone
0.36	GO:0031410	cytoplasmic vesicle

sp|Q9UPT8|ZC3H4_HUMAN
Zinc finger CCCH domain-containing protein 4
Search

ZC3H4

0.93	LOW QUALITY PROTEIN: zinc finger CCCH domain-containing protein 4

0.54	GO:0046872	metal ion binding
0.36	GO:0003723	RNA binding

0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol

sp|Q9UPT9|UBP22_HUMAN
Ubiquitin carboxyl-terminal hydrolase 22
Search

USP22

0.58	Ubiquitinyl hydrolase 1

0.73	GO:0016579	protein deubiquitination
0.70	GO:0006511	ubiquitin-dependent protein catabolic process
0.46	GO:0043967	histone H4 acetylation
0.46	GO:0016574	histone ubiquitination
0.46	GO:0045931	positive regulation of mitotic cell cycle
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0050821	protein stabilization
0.39	GO:0043065	positive regulation of apoptotic process

0.73	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.61	GO:0008270	zinc ion binding
0.48	GO:0010485	H4 histone acetyltransferase activity
0.47	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.43	GO:0019899	enzyme binding
0.41	GO:0061578	Lys63-specific deubiquitinase activity
0.40	GO:1990380	Lys48-specific deubiquitinase activity

0.45	GO:0016607	nuclear speck
0.45	GO:0000124	SAGA complex
0.30	GO:0016020	membrane

0.73

GO:0036459

sp|Q9UPU3|SORC3_HUMAN
VPS10 domain-containing receptor SorCS3
Search

SORCS3

0.91	VPS10 domain-containing receptor SorCS1 isoform c

0.55	GO:1900452	regulation of long term synaptic depression
0.52	GO:0007613	memory
0.52	GO:0007612	learning
0.36	GO:0007218	neuropeptide signaling pathway
0.36	GO:0048011	neurotrophin TRK receptor signaling pathway

0.36	GO:0008188	neuropeptide receptor activity
0.34	GO:0005515	protein binding

0.52	GO:0014069	postsynaptic density
0.33	GO:0005886	plasma membrane
0.33	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

sp|Q9UPU5|UBP24_HUMAN
Ubiquitin carboxyl-terminal hydrolase 24
Search

USP24

0.77	Ubiquitin carboxyl-terminal hydrolase 24

0.75	GO:0016579	protein deubiquitination
0.71	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0021551	central nervous system morphogenesis
0.42	GO:1904888	cranial skeletal system development

0.75

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

0.34	GO:0005654	nucleoplasm
0.30	GO:0044425	membrane part

0.75

GO:0036459

sp|Q9UPU7|TBD2B_HUMAN
TBC1 domain family member 2B
Search

TBC1D2B

0.94	TBC1 domain family member 2B isoform B

0.71	GO:0031338	regulation of vesicle fusion
0.71	GO:0090630	activation of GTPase activity
0.59	GO:0006886	intracellular protein transport
0.47	GO:1902017	regulation of cilium assembly

0.68	GO:0017137	Rab GTPase binding
0.65	GO:0005096	GTPase activator activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.64	GO:0005829	cytosol
0.58	GO:0012505	endomembrane system

sp|Q9UPU9|SMAG1_HUMAN
Protein Smaug homolog 1
Search

SAMD4A

0.97	Sterile alpha motif domain-containing protein 4

0.84	GO:0043488	regulation of mRNA stability
0.77	GO:0017148	negative regulation of translation
0.59	GO:0045727	positive regulation of translation
0.50	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.35	GO:0006629	lipid metabolic process
0.35	GO:0035556	intracellular signal transduction

0.85	GO:0030371	translation repressor activity
0.59	GO:0003723	RNA binding
0.37	GO:0004435	phosphatidylinositol phospholipase C activity

0.63	GO:0001650	fibrillar center
0.59	GO:0045202	synapse
0.58	GO:0030054	cell junction
0.56	GO:0005829	cytosol
0.49	GO:0000932	P-body

0.37	EC:3.1.4.11	GO:0004435
0.37	KEGG:R03435	GO:0004435

sp|Q9UPV0|CE164_HUMAN
Centrosomal protein of 164 kDa
Search

CEP164

0.84	Centrosomal protein of 164 kDa

0.80	GO:0060271	cilium assembly
0.45	GO:0000086	G2/M transition of mitotic cell cycle
0.44	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.43	GO:0140056	organelle localization by membrane tethering
0.43	GO:0051301	cell division
0.42	GO:0006281	DNA repair

0.41

GO:0005515

protein binding

0.86	GO:0097539	ciliary transition fiber
0.83	GO:0005814	centriole
0.78	GO:0005813	centrosome
0.69	GO:0005654	nucleoplasm
0.46	GO:0005615	extracellular space
0.40	GO:0005829	cytosol

sp|Q9UPV7|PHF24_HUMAN
PHD finger protein 24
Search

PHF24

0.97	PHD finger protein 24

0.64	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.62	GO:0032228	regulation of synaptic transmission, GABAergic
0.61	GO:0007214	gamma-aminobutyric acid signaling pathway
0.60	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway

0.54	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding

0.32

GO:0005856

cytoskeleton

sp|Q9UPV9|TRAK1_HUMAN
Trafficking kinesin-binding protein 1
Search

TRAK1

0.94	Trafficking kinesin-binding protein 1

0.87	GO:0098957	anterograde axonal transport of mitochondrion
0.84	GO:0008333	endosome to lysosome transport
0.50	GO:0050772	positive regulation of axonogenesis
0.49	GO:0048813	dendrite morphogenesis
0.41	GO:0006493	protein O-linked glycosylation
0.39	GO:0006605	protein targeting
0.39	GO:0006357	regulation of transcription by RNA polymerase II

0.85	GO:0050811	GABA receptor binding
0.52	GO:0030911	TPR domain binding

0.83	GO:1904115	axon cytoplasm
0.78	GO:0005769	early endosome
0.59	GO:0005739	mitochondrion
0.51	GO:0044295	axonal growth cone
0.48	GO:0030425	dendrite
0.47	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005634	nucleus

sp|Q9UPW0|FOXJ3_HUMAN
Forkhead box protein J3
Search

FOXJ3

0.97	Forkhead box protein J3

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:0030154	cell differentiation
0.45	GO:0009653	anatomical structure morphogenesis
0.36	GO:0006351	transcription, DNA-templated

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity

0.60

GO:0005634

nucleus

sp|Q9UPW5|CBPC1_HUMAN
Cytosolic carboxypeptidase 1
Search

AGTPBP1

0.92	ATP/GTP binding protein 1

0.86	GO:0021702	cerebellar Purkinje cell differentiation
0.68	GO:0035609	C-terminal protein deglutamylation
0.68	GO:0035610	protein side chain deglutamylation
0.64	GO:0021772	olfactory bulb development
0.64	GO:0007628	adult walking behavior
0.62	GO:0050905	neuromuscular process
0.62	GO:0001754	eye photoreceptor cell differentiation
0.62	GO:0060041	retina development in camera-type eye
0.61	GO:0006508	proteolysis
0.57	GO:0007005	mitochondrion organization

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.56	GO:0015631	tubulin binding

0.57	GO:0005730	nucleolus
0.53	GO:0005829	cytosol
0.48	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.78

EC:3.4.17

GO:0004181

sp|Q9UPW6|SATB2_HUMAN
DNA-binding protein SATB2
Search

SATB2

0.88	DNA-binding protein SATB

0.61	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain
0.60	GO:0002076	osteoblast development
0.58	GO:0060021	palate development
0.57	GO:0001764	neuron migration
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0048704	embryonic skeletal system morphogenesis
0.57	GO:0009880	embryonic pattern specification
0.57	GO:0051216	cartilage development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0003682	chromatin binding
0.55	GO:0000987	proximal promoter sequence-specific DNA binding
0.41	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.53	GO:0031974	membrane-enclosed lumen
0.52	GO:0005667	transcription factor complex
0.47	GO:0044446	intracellular organelle part
0.46	GO:1902494	catalytic complex
0.38	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|Q9UPW8|UN13A_HUMAN
Protein unc-13 homolog A
Search

UNC13A

0.92	Unc-13 homolog A

0.85	GO:0016082	synaptic vesicle priming
0.85	GO:0016188	synaptic vesicle maturation
0.84	GO:0035249	synaptic transmission, glutamatergic
0.62	GO:0035556	intracellular signal transduction
0.55	GO:1903861	positive regulation of dendrite extension
0.52	GO:0099525	presynaptic dense core vesicle exocytosis
0.51	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.51	GO:0016081	synaptic vesicle docking
0.51	GO:0031915	positive regulation of synaptic plasticity
0.50	GO:1900451	positive regulation of glutamate receptor signaling pathway

0.85	GO:0019992	diacylglycerol binding
0.74	GO:0005543	phospholipid binding
0.69	GO:0005509	calcium ion binding
0.42	GO:0017075	syntaxin-1 binding
0.41	GO:0047485	protein N-terminus binding
0.38	GO:0005516	calmodulin binding
0.37	GO:0030742	GTP-dependent protein binding
0.36	GO:0030507	spectrin binding
0.35	GO:0019904	protein domain specific binding
0.35	GO:0042803	protein homodimerization activity

0.76	GO:0098793	presynapse
0.51	GO:0044306	neuron projection terminus
0.49	GO:0031594	neuromuscular junction
0.49	GO:0030424	axon
0.45	GO:0005622	intracellular
0.40	GO:0097060	synaptic membrane
0.39	GO:0030054	cell junction
0.37	GO:0097470	ribbon synapse
0.37	GO:0060076	excitatory synapse
0.35	GO:0012505	endomembrane system

sp|Q9UPX0|TUTLB_HUMAN
Protein turtle homolog B
Search

IGSF9B

0.97	Immunoglobulin superfamily member 9B

0.74	GO:0097151	positive regulation of inhibitory postsynaptic potential
0.63	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.63

GO:0019900

kinase binding

0.71	GO:0060077	inhibitory synapse
0.65	GO:0043025	neuronal cell body
0.65	GO:0030425	dendrite
0.30	GO:0044425	membrane part

sp|Q9UPX6|K1024_HUMAN
UPF0258 protein KIAA1024
Search

0.30

GO:0044425

membrane part

sp|Q9UPX8|SHAN2_HUMAN
SH3 and multiple ankyrin repeat domains protein 2
Search

SHANK2

0.96	SH3 and multiple ankyrin repeat domains protein 2

0.86	GO:0060292	long term synaptic depression
0.86	GO:0071625	vocalization behavior
0.85	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.85	GO:0035176	social behavior
0.85	GO:0060291	long-term synaptic potentiation
0.85	GO:0035640	exploration behavior
0.84	GO:0007416	synapse assembly
0.83	GO:0007612	learning
0.82	GO:0030534	adult behavior
0.82	GO:0007613	memory

0.86	GO:0035255	ionotropic glutamate receptor binding
0.52	GO:0017124	SH3 domain binding
0.47	GO:0098919	structural constituent of postsynaptic density
0.47	GO:0030160	GKAP/Homer scaffold activity
0.43	GO:0008022	protein C-terminus binding

0.85	GO:0005883	neurofilament
0.85	GO:0001917	photoreceptor inner segment
0.85	GO:0008328	ionotropic glutamate receptor complex
0.84	GO:0043197	dendritic spine
0.84	GO:0001750	photoreceptor outer segment
0.79	GO:0045211	postsynaptic membrane
0.54	GO:0014069	postsynaptic density
0.54	GO:0031526	brush border membrane
0.54	GO:0060170	ciliary membrane
0.53	GO:0030426	growth cone

sp|Q9UPY3|DICER_HUMAN
Endoribonuclease Dicer
Search

DICER1

0.94	LOW QUALITY PROTEIN: endoribonuclease Dicer

0.78	GO:0031047	gene silencing by RNA
0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.64	GO:0036404	conversion of ds siRNA to ss siRNA
0.60	GO:0016441	posttranscriptional gene silencing
0.56	GO:0017148	negative regulation of translation
0.54	GO:0022618	ribonucleoprotein complex assembly
0.50	GO:0006309	apoptotic DNA fragmentation
0.49	GO:0034470	ncRNA processing
0.41	GO:0014040	positive regulation of Schwann cell differentiation
0.41	GO:0032290	peripheral nervous system myelin formation

0.77	GO:0004525	ribonuclease III activity
0.61	GO:0035197	siRNA binding
0.58	GO:0070883	pre-miRNA binding
0.55	GO:0019904	protein domain specific binding
0.55	GO:0003725	double-stranded RNA binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding
0.50	GO:0004530	deoxyribonuclease I activity

0.63	GO:0070578	RISC-loading complex
0.62	GO:0035068	micro-ribonucleoprotein complex
0.57	GO:0070062	extracellular exosome
0.49	GO:0016442	RISC complex
0.41	GO:0005634	nucleus
0.39	GO:0030426	growth cone
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon
0.38	GO:0034507	chromosome, centromeric outer repeat region

0.77

EC:3.1.26.3

GO:0004525

sp|Q9UPY5|XCT_HUMAN
Cystine/glutamate transporter
Search

SLC7A11

0.67	Anionic amino acid transporter light chain xCT

0.63	GO:0006865	amino acid transport
0.58	GO:0070527	platelet aggregation
0.55	GO:0055085	transmembrane transport
0.49	GO:0009636	response to toxic substance
0.45	GO:0006835	dicarboxylic acid transport
0.45	GO:0006836	neurotransmitter transport
0.43	GO:0042493	response to drug
0.40	GO:0070306	lens fiber cell differentiation
0.39	GO:0007420	brain development
0.37	GO:0006979	response to oxidative stress

0.57	GO:0022857	transmembrane transporter activity
0.45	GO:0005326	neurotransmitter transporter activity
0.33	GO:0005515	protein binding

0.53	GO:0009986	cell surface
0.42	GO:0005887	integral component of plasma membrane
0.39	GO:0005791	rough endoplasmic reticulum
0.37	GO:0005856	cytoskeleton

sp|Q9UPY6|WASF3_HUMAN
Wiskott-Aldrich syndrome protein family member 3
Search

WASF3

0.96	Wiskott-Aldrich syndrome protein family member 3

0.74	GO:0030036	actin cytoskeleton organization
0.60	GO:0031643	positive regulation of myelination
0.58	GO:0030032	lamellipodium assembly
0.58	GO:0014003	oligodendrocyte development
0.50	GO:0008360	regulation of cell shape
0.34	GO:0051258	protein polymerization
0.34	GO:0097435	supramolecular fiber organization

0.72

GO:0003779

actin binding

0.69	GO:0005856	cytoskeleton
0.56	GO:0030027	lamellipodium
0.38	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9UPY8|MARE3_HUMAN
Microtubule-associated protein RP/EB family member 3
Search

MAPRE3

0.68	Microtubule-associated protein RP/EB family member 3

0.62	GO:1903031	regulation of microtubule plus-end binding
0.62	GO:1904528	positive regulation of microtubule binding
0.56	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.50	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0070507	regulation of microtubule cytoskeleton organization
0.44	GO:0035372	protein localization to microtubule
0.42	GO:0032272	negative regulation of protein polymerization
0.42	GO:1902904	negative regulation of supramolecular fiber organization
0.41	GO:0051494	negative regulation of cytoskeleton organization
0.41	GO:0032273	positive regulation of protein polymerization

0.74	GO:0008017	microtubule binding
0.56	GO:0008022	protein C-terminus binding
0.55	GO:0019901	protein kinase binding
0.53	GO:0042802	identical protein binding
0.41	GO:0045296	cadherin binding
0.35	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.32	GO:0003723	RNA binding

0.72	GO:0005874	microtubule
0.55	GO:0030496	midbody
0.43	GO:0030981	cortical microtubule cytoskeleton
0.41	GO:0005819	spindle
0.41	GO:0005813	centrosome
0.39	GO:0031253	cell projection membrane
0.37	GO:0005794	Golgi apparatus
0.37	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol

0.35

EC:3.5

GO:0016810

sp|Q9UPZ3|HPS5_HUMAN
Hermansky-Pudlak syndrome 5 protein
Search

HPS5

0.96	Hermansky-Pudlak syndrome 5 homolog protein short-form variant

0.81	GO:0043473	pigmentation
0.78	GO:0007596	blood coagulation
0.61	GO:0006996	organelle organization
0.43	GO:0048076	regulation of compound eye pigmentation
0.41	GO:0030903	notochord development
0.40	GO:0007229	integrin-mediated signaling pathway

0.41

GO:0005515

protein binding

0.86	GO:0031084	BLOC-2 complex
0.34	GO:0005576	extracellular region
0.33	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UPZ6|THS7A_HUMAN
Thrombospondin type-1 domain-containing protein 7A
Search

THSD7A

0.78	Thrombospondin type-1 domain-containing protein 7A

0.33	GO:0001525	angiogenesis
0.32	GO:0030154	cell differentiation

0.34	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q9UPZ9|ICK_HUMAN
Serine/threonine-protein kinase ICK
Search

ICK

0.92	LOW QUALITY PROTEIN: serine/threonine-protein kinase ICK

0.63	GO:0006468	protein phosphorylation
0.53	GO:0035720	intraciliary anterograde transport
0.52	GO:0035721	intraciliary retrograde transport
0.48	GO:0060271	cilium assembly
0.42	GO:0035556	intracellular signal transduction
0.40	GO:0007275	multicellular organism development
0.38	GO:0010468	regulation of gene expression

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0000287	magnesium ion binding
0.37	GO:0004364	glutathione transferase activity
0.35	GO:0005515	protein binding

0.52	GO:0097542	ciliary tip
0.51	GO:0097546	ciliary base
0.49	GO:0036064	ciliary basal body
0.48	GO:0001650	fibrillar center
0.38	GO:0005829	cytosol

0.37

EC:2.5.1.18

GO:0004364

sp|Q9UQ03|COR2B_HUMAN
Coronin-2B
Search

CORO2B

0.68

Coronin

0.69

GO:0030036

actin cytoskeleton organization

0.78

GO:0051015

actin filament binding

0.54	GO:0017053	transcriptional repressor complex
0.45	GO:0015629	actin cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9UQ05|KCNH4_HUMAN
Potassium voltage-gated channel subfamily H member 4
Search

KCNH4

0.96	Potassium voltage-gated channel subfamily H member 4

0.75	GO:0034765	regulation of ion transmembrane transport
0.72	GO:0071805	potassium ion transmembrane transport
0.64	GO:0023014	signal transduction by protein phosphorylation
0.61	GO:0000160	phosphorelay signal transduction system
0.50	GO:0042391	regulation of membrane potential
0.34	GO:0043066	negative regulation of apoptotic process
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.76	GO:0005249	voltage-gated potassium channel activity
0.64	GO:0000155	phosphorelay sensor kinase activity
0.36	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0005622	intracellular
0.35	GO:0034705	potassium channel complex

0.64

EC:2.7.3

GO:0000155

sp|Q9UQ07|MOK_HUMAN
MAPK/MAK/MRK overlapping kinase
Search

MOK

0.92	MOK protein kinase

0.63	GO:0006468	protein phosphorylation
0.45	GO:0035556	intracellular signal transduction
0.42	GO:0060255	regulation of macromolecule metabolic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0097546	ciliary base
0.53	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

0.69

GO:0004674

sp|Q9UQ10|DHDH_HUMAN
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
Search

DHDH

0.78	Dihydrodiol dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.52	GO:0042843	D-xylose catabolic process
0.37	GO:0042981	regulation of apoptotic process
0.34	GO:0006091	generation of precursor metabolites and energy

0.56	GO:0047837	D-xylose 1-dehydrogenase (NADP+) activity
0.52	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
0.36	GO:0008746	NAD(P)+ transhydrogenase activity
0.35	GO:0050112	inositol 2-dehydrogenase activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0009055	electron transfer activity
0.33	GO:0047834	D-threo-aldose 1-dehydrogenase activity
0.33	GO:0005544	calcium-dependent phospholipid binding

0.30

GO:0031224

intrinsic component of membrane

0.56	EC:1.1.1.179	GO:0047837
0.56	KEGG:R01430	GO:0047837

sp|Q9UQ13|SHOC2_HUMAN
Leucine-rich repeat protein SHOC-2
Search

SHOC2

0.80	Leucine-rich repeat protein SHOC-2

0.84	GO:0046579	positive regulation of Ras protein signal transduction
0.62	GO:0007265	Ras protein signal transduction
0.60	GO:0043666	regulation of phosphoprotein phosphatase activity
0.40	GO:0008543	fibroblast growth factor receptor signaling pathway
0.36	GO:0006470	protein dephosphorylation

0.84	GO:0008157	protein phosphatase 1 binding
0.60	GO:0019888	protein phosphatase regulator activity
0.36	GO:0004721	phosphoprotein phosphatase activity

0.83	GO:0000164	protein phosphatase type 1 complex
0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane

0.36

GO:0004721

sp|Q9UQ16|DYN3_HUMAN
Dynamin-3
Search

DNM3

0.82	Dynamin-3 isoform b

0.55	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane
0.47	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.45	GO:0000266	mitochondrial fission
0.44	GO:0006898	receptor-mediated endocytosis
0.42	GO:0043112	receptor metabolic process
0.41	GO:0061025	membrane fusion
0.41	GO:1903423	positive regulation of synaptic vesicle recycling
0.40	GO:1903526	negative regulation of membrane tubulation
0.40	GO:0061002	negative regulation of dendritic spine morphogenesis
0.39	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.42	GO:0008017	microtubule binding
0.41	GO:0050998	nitric-oxide synthase binding
0.41	GO:0031798	type 1 metabotropic glutamate receptor binding
0.40	GO:0031802	type 5 metabotropic glutamate receptor binding
0.38	GO:0017124	SH3 domain binding
0.38	GO:0031749	D2 dopamine receptor binding
0.38	GO:0042802	identical protein binding
0.36	GO:0019901	protein kinase binding

0.53	GO:0001917	photoreceptor inner segment
0.49	GO:0045202	synapse
0.47	GO:0005874	microtubule
0.42	GO:0005739	mitochondrion
0.41	GO:0061829	basal tubulobulbar complex
0.41	GO:0061828	apical tubulobulbar complex
0.40	GO:0098590	plasma membrane region
0.40	GO:0005794	Golgi apparatus
0.39	GO:0031967	organelle envelope
0.39	GO:0043005	neuron projection

sp|Q9UQ26|RIMS2_HUMAN
Regulating synaptic membrane exocytosis protein 2
Search

RIMS2

0.80	LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 2

0.85	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.82	GO:0017157	regulation of exocytosis
0.55	GO:1903861	positive regulation of dendrite extension
0.50	GO:1902803	regulation of synaptic vesicle transport
0.50	GO:0098693	regulation of synaptic vesicle cycle
0.49	GO:0046928	regulation of neurotransmitter secretion
0.49	GO:0006886	intracellular protein transport
0.47	GO:0042391	regulation of membrane potential
0.41	GO:0061669	spontaneous neurotransmitter secretion
0.40	GO:0030073	insulin secretion

0.54	GO:0017137	Rab GTPase binding
0.49	GO:0044325	ion channel binding
0.47	GO:0046872	metal ion binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity

0.82	GO:0048786	presynaptic active zone
0.40	GO:0042734	presynaptic membrane
0.39	GO:0070062	extracellular exosome
0.38	GO:0030054	cell junction
0.37	GO:0005622	intracellular
0.35	GO:0060077	inhibitory synapse
0.33	GO:0043234	protein complex

sp|Q9UQ35|SRRM2_HUMAN
Serine/arginine repetitive matrix protein 2
Search

SRRM2

0.80	Serine/arginine repetitive matrix protein 2

0.73	GO:0000398	mRNA splicing, via spliceosome
0.32	GO:0006508	proteolysis

0.85	GO:0070742	C2H2 zinc finger domain binding
0.83	GO:0047485	protein N-terminus binding
0.39	GO:0003723	RNA binding
0.33	GO:0004252	serine-type endopeptidase activity

0.83	GO:0071007	U2-type catalytic step 2 spliceosome
0.83	GO:0015030	Cajal body
0.80	GO:0016607	nuclear speck
0.32	GO:0071006	U2-type catalytic step 1 spliceosome
0.30	GO:0044425	membrane part

0.33

GO:0004252

sp|Q9UQ49|NEUR3_HUMAN
Sialidase-3
Search

NEU3

0.56	Sialidase III

0.67	GO:0001573	ganglioside metabolic process
0.64	GO:0046479	glycosphingolipid catabolic process
0.64	GO:0046514	ceramide catabolic process
0.62	GO:0009313	oligosaccharide catabolic process
0.39	GO:0006516	glycoprotein catabolic process
0.38	GO:0051691	cellular oligosaccharide metabolic process
0.36	GO:0044275	cellular carbohydrate catabolic process
0.35	GO:0006465	signal peptide processing
0.32	GO:0043547	positive regulation of GTPase activity
0.32	GO:0007018	microtubule-based movement

0.75	GO:0004308	exo-alpha-sialidase activity
0.34	GO:0008233	peptidase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005096	GTPase activator activity
0.32	GO:0003777	microtubule motor activity
0.32	GO:0008017	microtubule binding
0.32	GO:0003779	actin binding
0.31	GO:0046872	metal ion binding

0.44	GO:0005886	plasma membrane
0.42	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0005737	cytoplasm
0.37	GO:0012505	endomembrane system
0.36	GO:1902494	catalytic complex
0.35	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.34	GO:0098796	membrane protein complex
0.32	GO:0015629	actin cytoskeleton

0.75

EC:3.2.1.18

GO:0004308

sp|Q9UQ52|CNTN6_HUMAN
Contactin-6
Search

CNTN6

0.94	Neural recognition molecule NB-3

0.76	GO:0030182	neuron differentiation
0.71	GO:0007155	cell adhesion
0.59	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.59	GO:0000904	cell morphogenesis involved in differentiation
0.57	GO:0120036	plasma membrane bounded cell projection organization
0.55	GO:0045747	positive regulation of Notch signaling pathway
0.54	GO:0006935	chemotaxis
0.53	GO:0006928	movement of cell or subcellular component
0.48	GO:0045665	negative regulation of neuron differentiation
0.38	GO:0007417	central nervous system development

0.75

GO:0005112

Notch binding

0.42	GO:0005886	plasma membrane
0.40	GO:0031225	anchored component of membrane
0.35	GO:0005576	extracellular region
0.34	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|Q9UQ53|MGT4B_HUMAN
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Search

MGAT4B

0.96	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

0.60	GO:0005975	carbohydrate metabolic process
0.55	GO:0006487	protein N-linked glycosylation
0.36	GO:0006491	N-glycan processing
0.34	GO:0043687	post-translational protein modification

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.52	GO:0008194	UDP-glycosyltransferase activity
0.42	GO:0140103	catalytic activity, acting on a glycoprotein
0.36	GO:0046872	metal ion binding

0.40	GO:0000139	Golgi membrane
0.35	GO:0005576	extracellular region
0.34	GO:0031982	vesicle
0.34	GO:0005788	endoplasmic reticulum lumen
0.32	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.69

GO:0016758

sp|Q9UQ72|PSG11_HUMAN
Pregnancy-specific beta-1-glycoprotein 11
Search

0.97	Pregnancy specific beta-1-glycoprotein 5

0.76	GO:0007565	female pregnancy
0.47	GO:0016477	cell migration
0.45	GO:0043317	regulation of cytotoxic T cell degranulation
0.44	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.44	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.44	GO:0030334	regulation of cell migration
0.43	GO:0043301	negative regulation of leukocyte degranulation
0.43	GO:0050860	negative regulation of T cell receptor signaling pathway
0.43	GO:0090505	epiboly involved in wound healing
0.42	GO:0050868	negative regulation of T cell activation

0.43	GO:0031005	filamin binding
0.42	GO:1990782	protein tyrosine kinase binding
0.42	GO:0019903	protein phosphatase binding
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0003779	actin binding
0.38	GO:0034235	GPI anchor binding
0.38	GO:0015125	bile acid transmembrane transporter activity
0.36	GO:0005516	calmodulin binding

0.49	GO:0005576	extracellular region
0.43	GO:0042101	T cell receptor complex
0.41	GO:0009986	cell surface
0.41	GO:0031982	vesicle
0.40	GO:0005911	cell-cell junction
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0031225	anchored component of membrane
0.38	GO:0005887	integral component of plasma membrane
0.38	GO:0031528	microvillus membrane
0.38	GO:0005766	primary lysosome

sp|Q9UQ74|PSG8_HUMAN
Pregnancy-specific beta-1-glycoprotein 8
Search

0.94	Pregnancy-specific beta-1-glycoprotein 8

0.81	GO:0007565	female pregnancy
0.44	GO:0050900	leukocyte migration
0.40	GO:0006952	defense response
0.37	GO:0043312	neutrophil degranulation

0.40

GO:0005515

protein binding

0.52	GO:0005576	extracellular region
0.41	GO:0031982	vesicle
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.33	GO:0044444	cytoplasmic part
0.30	GO:0044425	membrane part

sp|Q9UQ80|PA2G4_HUMAN
Proliferation-associated protein 2G4
Search

PA2G4

0.68	Proliferation-associated protein 2G4

0.39	GO:0043066	negative regulation of apoptotic process
0.38	GO:0051094	positive regulation of developmental process
0.38	GO:0045595	regulation of cell differentiation
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.37	GO:0048522	positive regulation of cellular process
0.36	GO:0006417	regulation of translation
0.36	GO:0006364	rRNA processing
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0007050	cell cycle arrest
0.34	GO:0008283	cell proliferation

0.39	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003723	RNA binding
0.34	GO:0003677	DNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0038132	neuregulin binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.33	GO:0030296	protein tyrosine kinase activator activity
0.33	GO:0046982	protein heterodimerization activity

0.47	GO:0005737	cytoplasm
0.38	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0016328	lateral plasma membrane
0.33	GO:0016323	basolateral plasma membrane
0.33	GO:0016324	apical plasma membrane

0.34

EC:2.7.10.1

GO:0004714

sp|Q9UQ84|EXO1_HUMAN
Exonuclease 1
Search

EXO1

0.81	Exonuclease 1

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.64	GO:0016446	somatic hypermutation of immunoglobulin genes
0.63	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.62	GO:0002312	B cell activation involved in immune response
0.61	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.39	GO:0000732	strand displacement
0.38	GO:0001325	formation of extrachromosomal circular DNA
0.38	GO:0090737	telomere maintenance via telomere trimming
0.38	GO:0051321	meiotic cell cycle

0.84	GO:0035312	5'-3' exodeoxyribonuclease activity
0.63	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.62	GO:0008297	single-stranded DNA exodeoxyribonuclease activity
0.60	GO:0048256	flap endonuclease activity
0.56	GO:0003682	chromatin binding
0.54	GO:0003677	DNA binding
0.36	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.35	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.52	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.45	GO:0005886	plasma membrane
0.34	GO:0005739	mitochondrion

0.36

EC:3.1.26.4

GO:0004523

sp|Q9UQ88|CD11A_HUMAN
Cyclin-dependent kinase 11A
Search

CDK11B

0.84	Cell division protein kinase 11

0.63	GO:0006468	protein phosphorylation
0.49	GO:2001234	negative regulation of apoptotic signaling pathway
0.49	GO:0007346	regulation of mitotic cell cycle
0.48	GO:0001824	blastocyst development
0.47	GO:0051783	regulation of nuclear division
0.46	GO:0010564	regulation of cell cycle process
0.41	GO:0007224	smoothened signaling pathway
0.38	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0051301	cell division
0.36	GO:0001558	regulation of cell growth

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0060089	molecular transducer activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.43	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9UQ90|SPG7_HUMAN
Paraplegin
Search

SPG7

0.65	Spastic paraplegia 7 (Pure and complicated autosomal recessive)

0.60	GO:0006508	proteolysis
0.58	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death
0.56	GO:0008089	anterograde axonal transport
0.36	GO:0006851	mitochondrial calcium ion transmembrane transport
0.34	GO:0007399	nervous system development
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0030155	regulation of cell adhesion
0.34	GO:0007155	cell adhesion
0.34	GO:0030163	protein catabolic process

0.70	GO:0004222	metalloendopeptidase activity
0.61	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0051082	unfolded protein binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0004176	ATP-dependent peptidase activity

0.59	GO:0005757	mitochondrial permeability transition pore complex
0.58	GO:0005745	m-AAA complex
0.55	GO:1904115	axon cytoplasm
0.35	GO:0005840	ribosome

0.70

GO:0004222

sp|Q9UQB3|CTND2_HUMAN
Catenin delta-2
Search

CTNND2

0.91	Catenin (cadherin-associated protein), delta 2b

0.77	GO:0098609	cell-cell adhesion
0.53	GO:0060997	dendritic spine morphogenesis
0.50	GO:0060828	regulation of canonical Wnt signaling pathway
0.42	GO:0001764	neuron migration
0.35	GO:0016055	Wnt signaling pathway
0.35	GO:0007612	learning
0.35	GO:0048167	regulation of synaptic plasticity
0.35	GO:0001763	morphogenesis of a branching structure
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription

0.51

GO:0008013

beta-catenin binding

0.52	GO:0043204	perikaryon
0.37	GO:0030425	dendrite
0.37	GO:0005912	adherens junction
0.35	GO:0014069	postsynaptic density
0.34	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|Q9UQB8|BAIP2_HUMAN
Brain-specific angiogenesis inhibitor 1-associated protein 2
Search

BAIAP2

0.94	Brain-specific angiogenesis inhibitor 1-associated protein 2

0.82	GO:0007009	plasma membrane organization
0.77	GO:0032956	regulation of actin cytoskeleton organization
0.57	GO:0051764	actin crosslink formation
0.54	GO:0051017	actin filament bundle assembly
0.52	GO:0016358	dendrite development
0.52	GO:0048167	regulation of synaptic plasticity
0.50	GO:0009617	response to bacterium
0.49	GO:0098609	cell-cell adhesion
0.47	GO:0008286	insulin receptor signaling pathway
0.47	GO:0008360	regulation of cell shape

0.85	GO:0008093	cytoskeletal adaptor activity
0.55	GO:0070064	proline-rich region binding
0.54	GO:0098641	cadherin binding involved in cell-cell adhesion
0.48	GO:0042802	identical protein binding
0.39	GO:0001221	transcription cofactor binding
0.39	GO:0097110	scaffold protein binding
0.38	GO:0030165	PDZ domain binding
0.35	GO:0008022	protein C-terminus binding

0.52	GO:0005913	cell-cell adherens junction
0.50	GO:0015629	actin cytoskeleton
0.49	GO:0043005	neuron projection
0.48	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.40	GO:0030175	filopodium
0.40	GO:0001726	ruffle
0.39	GO:0060076	excitatory synapse
0.38	GO:0014069	postsynaptic density
0.38	GO:0005791	rough endoplasmic reticulum

sp|Q9UQB9|AURKC_HUMAN
Aurora kinase C
Search

AURKB

0.96	Aurora kinase C

0.69	GO:0051255	spindle midzone assembly
0.68	GO:0035404	histone-serine phosphorylation
0.63	GO:0032467	positive regulation of cytokinesis
0.61	GO:0000278	mitotic cell cycle
0.61	GO:0031577	spindle checkpoint
0.61	GO:0048599	oocyte development
0.60	GO:0051321	meiotic cell cycle
0.58	GO:0000910	cytokinesis
0.58	GO:0007283	spermatogenesis
0.52	GO:0051231	spindle elongation

0.69	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0035173	histone kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.49	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.47	GO:0019900	kinase binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0046982	protein heterodimerization activity

0.77	GO:0032133	chromosome passenger complex
0.60	GO:0051233	spindle midzone
0.57	GO:0030496	midbody
0.56	GO:0000793	condensed chromosome
0.53	GO:0031616	spindle pole centrosome
0.52	GO:0000775	chromosome, centromeric region
0.50	GO:0000228	nuclear chromosome
0.50	GO:0005876	spindle microtubule
0.48	GO:0010369	chromocenter
0.48	GO:0072686	mitotic spindle

0.69

GO:0004674

sp|Q9UQC2|GAB2_HUMAN
GRB2-associated-binding protein 2
Search

GAB2

0.92	GRB2 associated binding protein 2

0.85	GO:0030316	osteoclast differentiation
0.79	GO:0008284	positive regulation of cell proliferation
0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.87

GO:0005068

transmembrane receptor protein tyrosine kinase adaptor activity

0.56	GO:0005886	plasma membrane
0.49	GO:0005737	cytoplasm

sp|Q9UQC9|CLCA2_HUMAN
Calcium-activated chloride channel regulator 2
Search

CLCA2

0.85	Calcium activated chloride channel

0.76	GO:1902476	chloride transmembrane transport
0.37	GO:0043276	anoikis
0.37	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.36	GO:0006508	proteolysis
0.36	GO:0007155	cell adhesion
0.34	GO:0006816	calcium ion transport

0.85	GO:0061778	intracellular chloride channel activity
0.72	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.52	GO:0022834	ligand-gated channel activity
0.38	GO:0008237	metallopeptidase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0004175	endopeptidase activity

0.54	GO:0031965	nuclear membrane
0.52	GO:0030054	cell junction
0.49	GO:0005829	cytosol
0.48	GO:0005887	integral component of plasma membrane
0.39	GO:0098590	plasma membrane region
0.38	GO:0045178	basal part of cell
0.37	GO:0005902	microvillus
0.37	GO:0031982	vesicle
0.36	GO:0045177	apical part of cell
0.36	GO:0005576	extracellular region

sp|Q9UQD0|SCN8A_HUMAN
Sodium channel protein type 8 subunit alpha
Search

SCN8A

0.66	Sodium voltage-gated channel alpha subunit 8

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.49	GO:0019228	neuronal action potential
0.48	GO:0086010	membrane depolarization during action potential
0.38	GO:0007626	locomotory behavior
0.38	GO:0048731	system development
0.37	GO:0050905	neuromuscular process
0.37	GO:0030534	adult behavior
0.37	GO:0007605	sensory perception of sound
0.37	GO:0061061	muscle structure development

0.84	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.40	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.35	GO:0031402	sodium ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.40	GO:0033268	node of Ranvier
0.39	GO:0030018	Z disc
0.38	GO:0043194	axon initial segment
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.34	GO:0031410	cytoplasmic vesicle

sp|Q9UQE7|SMC3_HUMAN
Structural maintenance of chromosomes protein 3
Search

sp|Q9UQF0|SYCY1_HUMAN
Syncytin-1
Search

ERVW-1

0.97

Syncytin

0.57	GO:0006949	syncytium formation
0.49	GO:0045026	plasma membrane fusion
0.39	GO:0060711	labyrinthine layer development
0.37	GO:0060674	placenta blood vessel development
0.33	GO:0019064	fusion of virus membrane with host plasma membrane
0.33	GO:0019062	virion attachment to host cell

0.62	GO:0036338	viral membrane
0.42	GO:0005886	plasma membrane
0.33	GO:0020002	host cell plasma membrane
0.33	GO:0055036	virion membrane
0.30	GO:0044425	membrane part

sp|Q9UQF2|JIP1_HUMAN
C-Jun-amino-terminal kinase-interacting protein 1
Search

MAPK8IP1

0.94	C-Jun-amino-terminal kinase-interacting protein 1

0.57	GO:0016310	phosphorylation
0.47	GO:0043508	negative regulation of JUN kinase activity
0.45	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.45	GO:0031098	stress-activated protein kinase signaling cascade
0.44	GO:0043410	positive regulation of MAPK cascade
0.41	GO:0016192	vesicle-mediated transport
0.38	GO:0006464	cellular protein modification process
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.59	GO:0016301	kinase activity
0.47	GO:0008432	JUN kinase binding
0.46	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.46	GO:0031434	mitogen-activated protein kinase kinase binding
0.46	GO:0005078	MAP-kinase scaffold activity
0.45	GO:0019894	kinesin binding
0.39	GO:0004860	protein kinase inhibitor activity
0.37	GO:0042802	identical protein binding

0.47	GO:0044294	dendritic growth cone
0.47	GO:0044302	dentate gyrus mossy fiber
0.46	GO:0044295	axonal growth cone
0.44	GO:0044297	cell body
0.43	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0045202	synapse
0.41	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0005829	cytosol
0.39	GO:0031966	mitochondrial membrane
0.39	GO:0005634	nucleus

sp|Q9UQG0|POK11_HUMAN
Endogenous retrovirus group K member 11 Pol protein
Search

0.96	Endogenous retrovirus group K member 7 Pol protein

0.69	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.68	GO:0006278	RNA-dependent DNA biosynthetic process
0.67	GO:0015074	DNA integration
0.62	GO:0006310	DNA recombination
0.42	GO:0045026	plasma membrane fusion
0.35	GO:0016032	viral process
0.35	GO:0006508	proteolysis

0.72	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.68	GO:0003964	RNA-directed DNA polymerase activity
0.62	GO:0008270	zinc ion binding
0.53	GO:0003677	DNA binding
0.45	GO:0005198	structural molecule activity
0.36	GO:0003887	DNA-directed DNA polymerase activity
0.36	GO:0070001	aspartic-type peptidase activity
0.35	GO:0004175	endopeptidase activity
0.35	GO:0003723	RNA binding

0.46	GO:0036338	viral membrane
0.38	GO:0005886	plasma membrane
0.36	GO:0019028	viral capsid
0.30	GO:0016021	integral component of membrane

0.72

EC:3.1.26.4

GO:0004523

sp|Q9UQK1|PPR3C_HUMAN
Protein phosphatase 1 regulatory subunit 3C
Search

PPP1R3C

0.86	Protein phosphatase 1 regulatory subunit

0.75	GO:0043666	regulation of phosphoprotein phosphatase activity
0.67	GO:0005977	glycogen metabolic process
0.53	GO:0009250	glucan biosynthetic process
0.41	GO:0005981	regulation of glycogen catabolic process
0.36	GO:0006470	protein dephosphorylation
0.35	GO:0005979	regulation of glycogen biosynthetic process
0.34	GO:0006605	protein targeting
0.33	GO:0001878	response to yeast

0.76	GO:0019888	protein phosphatase regulator activity
0.57	GO:0019903	protein phosphatase binding
0.36	GO:0004721	phosphoprotein phosphatase activity

0.39	GO:0000164	protein phosphatase type 1 complex
0.36	GO:0042587	glycogen granule
0.34	GO:0005829	cytosol
0.33	GO:0043231	intracellular membrane-bounded organelle

0.36

GO:0004721

sp|Q9UQL6|HDAC5_HUMAN
Histone deacetylase 5
Search

HDAC5

0.52	Histone deacetylase

0.80	GO:0070932	histone H3 deacetylation
0.78	GO:0040029	regulation of gene expression, epigenetic
0.57	GO:0010832	negative regulation of myotube differentiation
0.57	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0043393	regulation of protein binding
0.49	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0044093	positive regulation of molecular function

0.80	GO:0004407	histone deacetylase activity
0.77	GO:0034979	NAD-dependent protein deacetylase activity
0.56	GO:0005080	protein kinase C binding
0.55	GO:0070491	repressing transcription factor binding
0.55	GO:0042826	histone deacetylase binding
0.54	GO:0001085	RNA polymerase II transcription factor binding
0.54	GO:0001047	core promoter binding
0.53	GO:0046872	metal ion binding
0.39	GO:0001226	RNA polymerase II transcription corepressor binding
0.38	GO:0003682	chromatin binding

0.81	GO:0000118	histone deacetylase complex
0.52	GO:0016607	nuclear speck
0.49	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.38	GO:0090571	RNA polymerase II transcription repressor complex
0.36	GO:0000790	nuclear chromatin
0.36	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.80

EC:3.5.1.98

GO:0004407

sp|Q9UQM7|KCC2A_HUMAN
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Search

CAMK2A

0.97	Calcium/calmodulin-dependent protein kinase type II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.58	GO:0010666	positive regulation of cardiac muscle cell apoptotic process
0.56	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process
0.56	GO:0002931	response to ischemia
0.55	GO:0038166	angiotensin-activated signaling pathway
0.55	GO:0046928	regulation of neurotransmitter secretion
0.55	GO:0048168	regulation of neuronal synaptic plasticity
0.54	GO:0051928	positive regulation of calcium ion transport
0.54	GO:0048813	dendrite morphogenesis
0.54	GO:0018209	peptidyl-serine modification

0.81	GO:0004683	calmodulin-dependent protein kinase activity
0.77	GO:0005516	calmodulin binding
0.56	GO:0035254	glutamate receptor binding
0.56	GO:0009931	calcium-dependent protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.50	GO:0042803	protein homodimerization activity
0.35	GO:0032794	GTPase activating protein binding

0.54	GO:0014069	postsynaptic density
0.45	GO:0043005	neuron projection
0.44	GO:0005739	mitochondrion
0.39	GO:0042734	presynaptic membrane
0.37	GO:0030054	cell junction
0.36	GO:0099524	postsynaptic cytosol
0.35	GO:0099634	postsynaptic specialization membrane
0.35	GO:0030666	endocytic vesicle membrane
0.34	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.34	GO:0043025	neuronal cell body

0.81	EC:2.7.11.17	GO:0004683
0.33	KEGG:R00162	GO:0004707

sp|Q9UQN3|CHM2B_HUMAN
Charged multivesicular body protein 2b
Search

CHMP2B

0.96	Charged multivesicular body protein 2b-A

0.79	GO:0007034	vacuolar transport
0.56	GO:1902188	positive regulation of viral release from host cell
0.55	GO:0070050	neuron cellular homeostasis
0.55	GO:1901673	regulation of mitotic spindle assembly
0.54	GO:0000920	cell separation after cytokinesis
0.54	GO:0007080	mitotic metaphase plate congression
0.53	GO:0007032	endosome organization
0.53	GO:0010824	regulation of centrosome duplication
0.52	GO:0050890	cognition
0.52	GO:0006997	nucleus organization

0.52	GO:0045296	cadherin binding
0.50	GO:0019904	protein domain specific binding

0.55	GO:0000815	ESCRT III complex
0.54	GO:0005770	late endosome
0.51	GO:0005764	lysosome
0.49	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9UQP3|TENN_HUMAN
Tenascin-N
Search

0.10	Tenascin-N

0.71	GO:0007155	cell adhesion
0.63	GO:0045595	regulation of cell differentiation
0.63	GO:0048699	generation of neurons
0.63	GO:0042127	regulation of cell proliferation
0.63	GO:0051960	regulation of nervous system development
0.49	GO:0051971	positive regulation of transmission of nerve impulse
0.49	GO:0051093	negative regulation of developmental process
0.49	GO:0051241	negative regulation of multicellular organismal process
0.49	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.49	GO:0035641	locomotory exploration behavior

0.44	GO:0005178	integrin binding
0.41	GO:0042802	identical protein binding
0.33	GO:0046625	sphingolipid binding

0.74	GO:0031012	extracellular matrix
0.48	GO:0009986	cell surface
0.46	GO:1990026	hippocampal mossy fiber expansion
0.46	GO:0097442	CA3 pyramidal cell dendrite
0.46	GO:0045121	membrane raft
0.43	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

sp|Q9UQQ1|NALDL_HUMAN
N-acetylated-alpha-linked acidic dipeptidase-like protein
Search

NAALADL1

0.58	N-acetylated alpha-linked acidic dipeptidase like 1

0.46	GO:0006508	proteolysis
0.36	GO:0033572	transferrin transport
0.35	GO:0006879	cellular iron ion homeostasis
0.34	GO:0006898	receptor-mediated endocytosis

0.51	GO:0004180	carboxypeptidase activity
0.42	GO:0016805	dipeptidase activity
0.39	GO:0008237	metallopeptidase activity
0.36	GO:0004998	transferrin receptor activity
0.36	GO:0046872	metal ion binding
0.33	GO:0004252	serine-type endopeptidase activity

0.43	GO:0016324	apical plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.42

EC:3.4.13

GO:0016805

sp|Q9UQQ2|SH2B3_HUMAN
SH2B adapter protein 3
Search

SH2B3

0.97	SH2B adapter protein 3

0.75	GO:0009967	positive regulation of signal transduction
0.74	GO:0030097	hemopoiesis
0.60	GO:0048568	embryonic organ development
0.60	GO:0007165	signal transduction
0.55	GO:0030154	cell differentiation
0.43	GO:0030032	lamellipodium assembly
0.42	GO:0045840	positive regulation of mitotic nuclear division
0.42	GO:2000278	regulation of DNA biosynthetic process
0.38	GO:0007596	blood coagulation
0.34	GO:0045589	regulation of regulatory T cell differentiation

0.83	GO:0035591	signaling adaptor activity
0.59	GO:0004871	signal transducer activity
0.37	GO:0005515	protein binding
0.34	GO:0042301	phosphate ion binding
0.33	GO:0044877	macromolecular complex binding

0.43	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q9UQR0|SCML2_HUMAN
Sex comb on midleg-like protein 2
Search

0.74	Sex comb on midleg like 2 (Drosophila)

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0009952	anterior/posterior pattern specification
0.39	GO:0007283	spermatogenesis
0.39	GO:0006338	chromatin remodeling
0.30	GO:0044237	cellular metabolic process
0.30	GO:1901362	organic cyclic compound biosynthetic process
0.30	GO:0044238	primary metabolic process
0.30	GO:0009653	anatomical structure morphogenesis

0.30	GO:0005515	protein binding
0.30	GO:1901363	heterocyclic compound binding
0.30	GO:0003700	DNA binding transcription factor activity
0.30	GO:0097159	organic cyclic compound binding

0.61	GO:0005634	nucleus
0.43	GO:0044446	intracellular organelle part
0.42	GO:0043234	protein complex
0.37	GO:0005694	chromosome

sp|Q9UQR1|ZN148_HUMAN
Zinc finger protein 148
Search

ZNF148

0.50	Zinc finger protein 148

0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0007276	gamete generation
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0030097	hemopoiesis
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0006461	protein complex assembly
0.30	GO:0060322	head development
0.30	GO:0050896	response to stimulus
0.30	GO:0048857	neural nucleus development
0.30	GO:0007417	central nervous system development

0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.30	GO:0005515	protein binding

0.49	GO:0005794	Golgi apparatus
0.45	GO:0005634	nucleus

sp|Q9UQV4|LAMP3_HUMAN
Lysosome-associated membrane glycoprotein 3
Search

LAMP3

0.96	Lysosome-associated membrane glycoprotein 3

0.73	GO:0035455	response to interferon-alpha
0.71	GO:1901799	negative regulation of proteasomal protein catabolic process
0.70	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.69	GO:1903900	regulation of viral life cycle
0.62	GO:0010506	regulation of autophagy
0.61	GO:0010628	positive regulation of gene expression
0.47	GO:0002250	adaptive immune response
0.39	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.39	GO:0044409	entry into host
0.38	GO:0019058	viral life cycle

0.82	GO:0005765	lysosomal membrane
0.67	GO:0005769	early endosome
0.66	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0097233	alveolar lamellar body membrane
0.49	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9WJR5|POK19_HUMAN
Endogenous retrovirus group K member 19 Pol protein
Search

POL

0.30	Integrase DNA binding domain

0.69	GO:0006278	RNA-dependent DNA biosynthetic process
0.68	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.65	GO:0015074	DNA integration
0.47	GO:0006310	DNA recombination
0.45	GO:0044826	viral genome integration into host DNA
0.45	GO:0075713	establishment of integrated proviral latency
0.41	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.41	GO:0044409	entry into host
0.39	GO:0006508	proteolysis

0.71	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.69	GO:0003964	RNA-directed DNA polymerase activity
0.60	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.41	GO:0070001	aspartic-type peptidase activity
0.41	GO:0004170	dUTP diphosphatase activity
0.40	GO:0003887	DNA-directed DNA polymerase activity
0.40	GO:0004175	endopeptidase activity
0.39	GO:0005198	structural molecule activity
0.32	GO:1901265	nucleoside phosphate binding

0.40	GO:0044423	virion part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.71	EC:3.1.26.4	GO:0004523
0.41	KEGG:R02100	GO:0004170

sp|Q9XRX5|HHLA3_HUMAN
HERV-H LTR-associating protein 3
Search

sp|Q9Y210|TRPC6_HUMAN
Short transient receptor potential channel 6
Search

TRPC6

0.94	Short transient receptor potential channel 6

0.76	GO:0070588	calcium ion transmembrane transport
0.58	GO:0051480	regulation of cytosolic calcium ion concentration
0.56	GO:0006828	manganese ion transport
0.54	GO:0051928	positive regulation of calcium ion transport
0.54	GO:0032414	positive regulation of ion transmembrane transporter activity
0.51	GO:0007338	single fertilization
0.42	GO:0050774	negative regulation of dendrite morphogenesis
0.41	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.41	GO:0070301	cellular response to hydrogen peroxide
0.41	GO:0071456	cellular response to hypoxia

0.79	GO:0005262	calcium channel activity
0.55	GO:0070679	inositol 1,4,5 trisphosphate binding
0.50	GO:0042803	protein homodimerization activity
0.41	GO:0051117	ATPase binding
0.40	GO:0042805	actinin binding
0.40	GO:0030276	clathrin binding
0.38	GO:0003779	actin binding

0.59	GO:0036057	slit diaphragm
0.45	GO:0005887	integral component of plasma membrane
0.39	GO:0005737	cytoplasm
0.38	GO:0005801	cis-Golgi network
0.35	GO:0005635	nuclear envelope

sp|Q9Y215|COLQ_HUMAN
Acetylcholinesterase collagenic tail peptide
Search

COLQ

0.90	Collagen like tail subunit of asymmetric acetylcholinesterase

0.69	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.66	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.57	GO:0090150	establishment of protein localization to membrane
0.39	GO:0042135	neurotransmitter catabolic process
0.38	GO:0001561	fatty acid alpha-oxidation
0.37	GO:0008291	acetylcholine metabolic process
0.37	GO:0007271	synaptic transmission, cholinergic
0.36	GO:0051259	protein oligomerization
0.36	GO:0042447	hormone catabolic process
0.35	GO:0042737	drug catabolic process

0.43	GO:0030976	thiamine pyrophosphate binding
0.41	GO:0000287	magnesium ion binding
0.39	GO:0016829	lyase activity
0.37	GO:0005515	protein binding
0.36	GO:0008201	heparin binding
0.34	GO:0005198	structural molecule activity

0.65	GO:0031594	neuromuscular junction
0.64	GO:0005581	collagen trimer
0.59	GO:0030054	cell junction
0.47	GO:0005886	plasma membrane
0.39	GO:0005605	basal lamina
0.37	GO:0043083	synaptic cleft
0.36	GO:0005777	peroxisome
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.39

EC:4

GO:0016829

sp|Q9Y216|MTMR7_HUMAN
Myotubularin-related protein 7
Search

MTMR7

0.93	Myotubularin-related protein 7 isoform B

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.45	GO:0046855	inositol phosphate dephosphorylation
0.36	GO:0006661	phosphatidylinositol biosynthetic process

0.84	GO:0052866	phosphatidylinositol phosphate phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.41	GO:0016312	inositol bisphosphate phosphatase activity
0.36	GO:0005515	protein binding

0.42	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.74

GO:0004725

sp|Q9Y217|MTMR6_HUMAN
Myotubularin-related protein 6
Search

MTMR6

0.95	LOW QUALITY PROTEIN: myotubularin-related protein 6

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.49	GO:0071805	potassium ion transmembrane transport
0.45	GO:0010506	regulation of autophagy
0.35	GO:0006661	phosphatidylinositol biosynthetic process
0.34	GO:0014065	phosphatidylinositol 3-kinase signaling
0.34	GO:0000187	activation of MAPK activity
0.34	GO:0001568	blood vessel development
0.34	GO:0000165	MAPK cascade

0.84	GO:0052866	phosphatidylinositol phosphate phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0015269	calcium-activated potassium channel activity
0.34	GO:0004722	protein serine/threonine phosphatase activity
0.34	GO:0004708	MAP kinase kinase activity
0.33	GO:0005515	protein binding

0.52	GO:0005635	nuclear envelope
0.39	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0004725

sp|Q9Y219|JAG2_HUMAN
Protein jagged-2
Search

sp|Q9Y221|NIP7_HUMAN
60S ribosome subunit biogenesis protein NIP7 homolog
Search

NIP7

0.81	60S ribosome subunit biogenesis protein NIP7 homolog

0.73	GO:0042255	ribosome assembly
0.45	GO:0042273	ribosomal large subunit biogenesis

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.47	GO:0030687	preribosome, large subunit precursor
0.46	GO:0005829	cytosol
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part

sp|Q9Y222|DMTF1_HUMAN
Cyclin-D-binding Myb-like transcription factor 1
Search

DMTF1

0.96	Cyclin D binding myb like transcription factor 1

0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0030154	cell differentiation
0.40	GO:0006366	transcription by RNA polymerase II
0.39	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0007049	cell cycle
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process

0.54	GO:0003677	DNA binding
0.48	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0016746	transferase activity, transferring acyl groups

0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.33	GO:0005840	ribosome

0.33

GO:0016746

sp|Q9Y223|GLCNE_HUMAN
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
Search

GNE

0.93	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

0.79	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.57	GO:0016310	phosphorylation
0.46	GO:0006045	N-acetylglucosamine biosynthetic process
0.40	GO:0006054	N-acetylneuraminate metabolic process
0.40	GO:0044262	cellular carbohydrate metabolic process
0.35	GO:0007155	cell adhesion
0.34	GO:0046394	carboxylic acid biosynthetic process

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.59	GO:0016301	kinase activity
0.46	GO:0008761	UDP-N-acetylglucosamine 2-epimerase activity
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.37

GO:0005829

cytosol

0.66

EC:3.2.1

GO:0004553

sp|Q9Y224|CN166_HUMAN
UPF0568 protein C14orf166
Search

RTRAF

0.43	Guanine nucleotide-binding protein subunit gamma

0.77	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.76	GO:0006469	negative regulation of protein kinase activity
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0006351	transcription, DNA-templated
0.39	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0051236	establishment of RNA localization
0.38	GO:0050657	nucleic acid transport
0.36	GO:0016032	viral process

0.81	GO:0000993	RNA polymerase II core binding
0.69	GO:0042802	identical protein binding
0.57	GO:0003723	RNA binding
0.39	GO:0003677	DNA binding
0.38	GO:0004871	signal transducer activity

0.82	GO:0072669	tRNA-splicing ligase complex
0.77	GO:0072686	mitotic spindle
0.75	GO:0048471	perinuclear region of cytoplasm
0.74	GO:0005813	centrosome
0.66	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:1905360	GTPase complex
0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0098797	plasma membrane protein complex

sp|Q9Y225|RNF24_HUMAN
RING finger protein 24
Search

RNF24

0.97	Ring finger protein 24

0.49	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.49	GO:0000209	protein polyubiquitination
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation

0.56	GO:0008270	zinc ion binding
0.47	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.49	GO:0005794	Golgi apparatus
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008138

sp|Q9Y226|S22AD_HUMAN
Solute carrier family 22 member 13
Search

SLC22A13

0.95	Solute carrier family 22 (Organic anion transporter), member 13

0.66	GO:2001142	nicotinate transport
0.63	GO:0015747	urate transport
0.57	GO:0043252	sodium-independent organic anion transport
0.55	GO:0055085	transmembrane transport
0.48	GO:0015698	inorganic anion transport
0.37	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.36	GO:0015695	organic cation transport
0.34	GO:0035634	response to stilbenoid
0.34	GO:0046415	urate metabolic process
0.33	GO:0008643	carbohydrate transport

0.66	GO:0090416	nicotinate transmembrane transporter activity
0.57	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.54	GO:0005452	inorganic anion exchanger activity
0.36	GO:0015101	organic cation transmembrane transporter activity
0.33	GO:0015301	anion:anion antiporter activity
0.32	GO:0005515	protein binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0016324	apical plasma membrane
0.47	GO:0005887	integral component of plasma membrane
0.38	GO:0070062	extracellular exosome
0.38	GO:0016323	basolateral plasma membrane
0.33	GO:0009897	external side of plasma membrane

0.32

GO:0004674

sp|Q9Y227|ENTP4_HUMAN
Ectonucleoside triphosphate diphosphohydrolase 4
Search

ENTPD4

0.96	Ectonucleoside triphosphate diphosphohydrolase 4

0.57	GO:0009195	pyrimidine ribonucleoside diphosphate catabolic process
0.57	GO:0046048	UDP metabolic process
0.57	GO:0009222	pyrimidine ribonucleotide catabolic process
0.51	GO:0046133	pyrimidine ribonucleoside catabolic process
0.36	GO:0034656	nucleobase-containing small molecule catabolic process

0.56	GO:0045134	uridine-diphosphatase activity
0.35	GO:0017111	nucleoside-triphosphatase activity

0.57	GO:0097636	intrinsic component of autophagosome membrane
0.54	GO:0031166	integral component of vacuolar membrane
0.52	GO:0030173	integral component of Golgi membrane
0.35	GO:0031410	cytoplasmic vesicle

0.56	EC:3.6.1.6	GO:0045134
0.56	KEGG:R00155	GO:0045134

sp|Q9Y228|T3JAM_HUMAN
TRAF3-interacting JNK-activating modulator
Search

TRAF3IP3

0.97	TRAF3-interacting JNK-activating modulator

0.31

GO:0055114

oxidation-reduction process

0.35	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.32	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

sp|Q9Y230|RUVB2_HUMAN
RuvB-like 2
Search

RUVBL2

0.66	RuvB-like helicase

0.70	GO:0032508	DNA duplex unwinding
0.62	GO:0006281	DNA repair
0.58	GO:0006310	DNA recombination
0.58	GO:0016569	covalent chromatin modification
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0071899	negative regulation of estrogen receptor binding
0.54	GO:0090202	gene looping

0.81	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0001094	TFIID-class transcription factor binding
0.52	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.51	GO:0051117	ATPase binding
0.51	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.50	GO:0031490	chromatin DNA binding

0.83	GO:0097255	R2TP complex
0.80	GO:0035267	NuA4 histone acetyltransferase complex
0.80	GO:0031011	Ino80 complex
0.54	GO:0000812	Swr1 complex
0.51	GO:0005719	nuclear euchromatin
0.51	GO:0071339	MLL1 complex
0.48	GO:0005813	centrosome
0.45	GO:0005829	cytosol
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0070062	extracellular exosome

0.81

EC:3.6.1

GO:0043141

sp|Q9Y231|FUT9_HUMAN
Alpha-(1,3)-fucosyltransferase 9
Search

FUT9

0.74	Fucosyltransferase 9

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.38	GO:0007399	nervous system development
0.35	GO:0042355	L-fucose catabolic process

0.81

GO:0008417

fucosyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

sp|Q9Y232|CDYL1_HUMAN
Chromodomain Y-like protein
Search

CDYL

0.94	Chromodomain Y like

0.52	GO:0120093	regulation of peptidyl-lysine crotonylation
0.47	GO:0060816	random inactivation of X chromosome
0.45	GO:0031400	negative regulation of protein modification process
0.44	GO:0007283	spermatogenesis
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0007281	germ cell development
0.40	GO:0016573	histone acetylation
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0030041	actin filament polymerization

0.52	GO:0120092	crotonyl-CoA hydratase activity
0.48	GO:0140034	methylation-dependent protein binding
0.46	GO:0042393	histone binding
0.46	GO:0003714	transcription corepressor activity
0.46	GO:0030674	protein binding, bridging
0.42	GO:0003682	chromatin binding
0.40	GO:0004402	histone acetyltransferase activity

0.58	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.40	GO:0005694	chromosome
0.39	GO:0044446	intracellular organelle part
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0004402

sp|Q9Y233|PDE10_HUMAN
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Search

PDE10A

0.55	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.53	GO:0043949	regulation of cAMP-mediated signaling
0.52	GO:0010738	regulation of protein kinase A signaling
0.39	GO:0046069	cGMP catabolic process
0.38	GO:0006198	cAMP catabolic process

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.53	GO:0030552	cAMP binding
0.38	GO:0030553	cGMP binding
0.34	GO:0008144	drug binding

0.38	GO:0043204	perikaryon
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:3.1.4.17

GO:0004114

sp|Q9Y234|LIPT_HUMAN
Lipoyltransferase 1, mitochondrial
Search

LIPT1

0.87	LOW QUALITY PROTEIN: lipoyltransferase 1, mitochondrial

0.77	GO:0009249	protein lipoylation
0.34	GO:0006629	lipid metabolic process
0.33	GO:0006998	nuclear envelope organization
0.32	GO:0034641	cellular nitrogen compound metabolic process

0.49	GO:0016979	lipoate-protein ligase activity
0.36	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0043495	protein membrane anchor

0.44	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0019013	viral nucleocapsid
0.33	GO:0044446	intracellular organelle part
0.33	GO:1990904	ribonucleoprotein complex
0.32	GO:0012505	endomembrane system
0.32	GO:0005634	nucleus
0.32	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:6.3.4

GO:0016979

sp|Q9Y235|ABEC2_HUMAN
C->U-editing enzyme APOBEC-2
Search

APOBEC2

0.97	Apolipoprotein B mRNA editing enzyme catalytic subunit 2

0.65	GO:0016554	cytidine to uridine editing
0.63	GO:0080111	DNA demethylation
0.61	GO:0009972	cytidine deamination
0.59	GO:0016556	mRNA modification
0.48	GO:0070654	sensory epithelium regeneration
0.47	GO:0043697	cell dedifferentiation
0.46	GO:0043388	positive regulation of DNA binding
0.45	GO:0060538	skeletal muscle organ development
0.39	GO:0006397	mRNA processing
0.38	GO:0001947	heart looping

0.71	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.63	GO:0008270	zinc ion binding
0.56	GO:0042802	identical protein binding
0.56	GO:0019239	deaminase activity
0.33	GO:0003723	RNA binding

0.30

GO:0016020

membrane

0.71

EC:3.5.4

GO:0016814

sp|Q9Y236|OSGI2_HUMAN
Oxidative stress-induced growth inhibitor 2
Search

OSGIN2

0.97	Oxidative stress-induced growth inhibitor 2

0.80	GO:0030308	negative regulation of cell growth
0.67	GO:0043065	positive regulation of apoptotic process
0.59	GO:0010469	regulation of receptor activity
0.38	GO:0051321	meiotic cell cycle
0.36	GO:0007009	plasma membrane organization
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0055085	transmembrane transport

0.61	GO:0008083	growth factor activity
0.35	GO:0003779	actin binding
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0022857	transmembrane transporter activity

0.30

GO:0016020

membrane

0.34

GO:0016491

sp|Q9Y237|PIN4_HUMAN
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4
Search

PIN4

0.49	Peptidyl-prolyl cis-trans isomerase

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.36	GO:0006364	rRNA processing

0.71	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.39	GO:0003681	bent DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.46	GO:0005730	nucleolus
0.40	GO:0005819	spindle
0.37	GO:0030684	preribosome
0.37	GO:0005759	mitochondrial matrix
0.36	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0003755

sp|Q9Y238|DLEC1_HUMAN
Deleted in lung and esophageal cancer protein 1
Search

DLEC1

0.97	Deleted in lung and esophageal cancer protein 1

0.79

GO:0008285

negative regulation of cell proliferation

0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51

GO:0005829

cytosol

sp|Q9Y239|NOD1_HUMAN
Nucleotide-binding oligomerization domain-containing protein 1
Search

NOD1

0.96	Nucleotide-binding oligomerization domain-containing protein 1

0.71	GO:0042981	regulation of apoptotic process
0.66	GO:0042228	interleukin-8 biosynthetic process
0.64	GO:0071225	cellular response to muramyl dipeptide
0.63	GO:0002606	positive regulation of dendritic cell antigen processing and presentation
0.62	GO:1904417	positive regulation of xenophagy
0.62	GO:0016045	detection of bacterium
0.61	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.60	GO:0032760	positive regulation of tumor necrosis factor production
0.60	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.59	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.63	GO:0050700	CARD domain binding
0.55	GO:0042803	protein homodimerization activity
0.37	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0042834	peptidoglycan binding

0.59	GO:0016323	basolateral plasma membrane
0.40	GO:0005737	cytoplasm
0.38	GO:0016324	apical plasma membrane

sp|Q9Y240|CLC11_HUMAN
C-type lectin domain family 11 member A
Search

CLEC11A

0.97	Stem cell growth factor; lymphocyte secreted C-type lectin

0.65	GO:0008284	positive regulation of cell proliferation
0.62	GO:0010469	regulation of receptor activity
0.46	GO:0001503	ossification

0.64	GO:0008083	growth factor activity
0.62	GO:0030246	carbohydrate binding

0.56	GO:0005576	extracellular region
0.36	GO:0005737	cytoplasm

sp|Q9Y241|HIG1A_HUMAN
HIG1 domain family member 1A, mitochondrial
Search

HIGD1A

0.59	Putative growth hormone like protein-1

0.51	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.49	GO:0071456	cellular response to hypoxia
0.49	GO:0042149	cellular response to glucose starvation
0.47	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.35	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0032259	methylation

0.33

GO:0008168

methyltransferase activity

0.42	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.41	GO:0019866	organelle inner membrane
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0070469	respiratory chain
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0008168

sp|Q9Y242|TCF19_HUMAN
Transcription factor 19
Search

TCF19

0.97	LOW QUALITY PROTEIN: transcription factor 19

0.46	GO:0044342	type B pancreatic cell proliferation
0.44	GO:0000082	G1/S transition of mitotic cell cycle
0.42	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0097659	nucleic acid-templated transcription
0.40	GO:0031323	regulation of cellular metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0009889	regulation of biosynthetic process
0.40	GO:0080090	regulation of primary metabolic process
0.39	GO:0010467	gene expression
0.38	GO:0034645	cellular macromolecule biosynthetic process

0.53	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.36	GO:0003700	DNA binding transcription factor activity

0.44

GO:0005634

nucleus

sp|Q9Y243|AKT3_HUMAN
RAC-gamma serine/threonine-protein kinase
Search

AKT3

0.76	RAC-gamma serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.58	GO:1905653	positive regulation of artery morphogenesis
0.57	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.56	GO:2000773	negative regulation of cellular senescence
0.56	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.56	GO:0045793	positive regulation of cell size
0.55	GO:0048873	homeostasis of number of cells within a tissue
0.55	GO:0048854	brain morphogenesis
0.53	GO:0000002	mitochondrial genome maintenance
0.52	GO:0032008	positive regulation of TOR signaling

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0030235	nitric-oxide synthase regulator activity
0.35	GO:0071889	14-3-3 protein binding
0.35	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.34	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.35	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.34	GO:0036064	ciliary basal body
0.34	GO:0005819	spindle
0.34	GO:0005886	plasma membrane
0.34	GO:0005911	cell-cell junction
0.33	GO:0031982	vesicle
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005739	mitochondrion
0.32	GO:0043234	protein complex

0.70

GO:0004674

sp|Q9Y244|POMP_HUMAN
Proteasome maturation protein
Search

POMP

0.95	Proteasome maturation protein (Fragment)

0.81	GO:0043248	proteasome assembly
0.33	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.33	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.33

GO:0005515

protein binding

0.62	GO:1905369	endopeptidase complex
0.52	GO:0043234	protein complex
0.49	GO:0016607	nuclear speck
0.39	GO:0005737	cytoplasm
0.37	GO:0012505	endomembrane system
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y247|FA50B_HUMAN
Protein FAM50B
Search

FAM50A

0.92	XAP-5 protein (Predicted)

0.36	GO:0071526	semaphorin-plexin signaling pathway
0.35	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0007283	spermatogenesis
0.34	GO:0015031	protein transport
0.32	GO:0016310	phosphorylation

0.36	GO:0017154	semaphorin receptor activity
0.35	GO:0005093	Rab GDP-dissociation inhibitor activity
0.35	GO:0005096	GTPase activator activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.51	GO:0045171	intercellular bridge
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9Y248|PSF2_HUMAN
DNA replication complex GINS protein PSF2
Search

GINS2

0.75	DNA replication complex GINS protein PSF2

0.66	GO:0006260	DNA replication
0.51	GO:0000727	double-strand break repair via break-induced replication
0.47	GO:1903047	mitotic cell cycle process
0.47	GO:0032392	DNA geometric change
0.42	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.39	GO:0030261	chromosome condensation
0.37	GO:0022616	DNA strand elongation
0.35	GO:0032784	regulation of DNA-templated transcription, elongation
0.33	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.33	GO:0006000	fructose metabolic process

0.51	GO:0043138	3'-5' DNA helicase activity
0.34	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.33	GO:0003873	6-phosphofructo-2-kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.48	GO:0032993	protein-DNA complex
0.47	GO:0044427	chromosomal part
0.46	GO:0031974	membrane-enclosed lumen
0.41	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.33	EC:2.7.1.105	GO:0003873
0.33	KEGG:R02732	GO:0003873

sp|Q9Y250|LZTS1_HUMAN
Leucine zipper putative tumor suppressor 1
Search

LZTS1

0.96	Leucine zipper tumor suppressor 1

0.81	GO:0044772	mitotic cell cycle phase transition
0.63	GO:0016242	negative regulation of macroautophagy
0.39	GO:0048814	regulation of dendrite morphogenesis
0.38	GO:0048167	regulation of synaptic plasticity
0.37	GO:0051255	spindle midzone assembly
0.37	GO:0030178	negative regulation of Wnt signaling pathway
0.37	GO:0016055	Wnt signaling pathway
0.37	GO:0051301	cell division
0.37	GO:0051013	microtubule severing
0.36	GO:0051168	nuclear export

0.74	GO:0008017	microtubule binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003677	DNA binding
0.32	GO:0008013	beta-catenin binding

0.41	GO:0043197	dendritic spine
0.40	GO:0014069	postsynaptic density
0.40	GO:0045211	postsynaptic membrane
0.39	GO:0043198	dendritic shaft
0.39	GO:0030054	cell junction
0.38	GO:0016324	apical plasma membrane
0.38	GO:0044297	cell body
0.36	GO:0030496	midbody
0.36	GO:0005815	microtubule organizing center
0.36	GO:0005874	microtubule

sp|Q9Y251|HPSE_HUMAN
Heparanase
Search

HPSE

0.97	Heparanase

0.62	GO:0030200	heparan sulfate proteoglycan catabolic process
0.60	GO:0060055	angiogenesis involved in wound healing
0.60	GO:0033690	positive regulation of osteoblast proliferation
0.59	GO:0051797	regulation of hair follicle development
0.59	GO:0010575	positive regulation of vascular endothelial growth factor production
0.59	GO:0042635	positive regulation of hair cycle
0.59	GO:0030194	positive regulation of blood coagulation
0.58	GO:0045684	positive regulation of epidermis development
0.58	GO:0051897	positive regulation of protein kinase B signaling
0.57	GO:0007160	cell-matrix adhesion

0.66	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.61	GO:0045545	syndecan binding
0.49	GO:0046983	protein dimerization activity
0.40	GO:0043395	heparan sulfate proteoglycan binding
0.35	GO:0047293	4-hydroxybenzoate nonaprenyltransferase activity
0.35	GO:0002083	4-hydroxybenzoate decaprenyltransferase activity
0.33	GO:0004386	helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005764	lysosome
0.54	GO:0045121	membrane raft
0.49	GO:0005654	nucleoplasm
0.47	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0098852	lytic vacuole membrane
0.37	GO:0035580	specific granule lumen
0.36	GO:0005775	vacuolar lumen
0.34	GO:0031305	integral component of mitochondrial inner membrane
0.32	GO:0005886	plasma membrane

0.66

EC:3.2

GO:0016798

sp|Q9Y252|RNF6_HUMAN
E3 ubiquitin-protein ligase RNF6
Search

RNF6

0.82	Ring finger protein, LIM domain interacting

0.86	GO:0044314	protein K27-linked ubiquitination
0.85	GO:0085020	protein K6-linked ubiquitination
0.85	GO:0060765	regulation of androgen receptor signaling pathway
0.71	GO:0045893	positive regulation of transcription, DNA-templated
0.70	GO:0030517	negative regulation of axon extension
0.69	GO:0070936	protein K48-linked ubiquitination
0.62	GO:0006511	ubiquitin-dependent protein catabolic process
0.57	GO:0010498	proteasomal protein catabolic process
0.43	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.37	GO:1900095	regulation of dosage compensation by inactivation of X chromosome

0.84	GO:0050681	androgen receptor binding
0.72	GO:0004842	ubiquitin-protein transferase activity
0.65	GO:0061659	ubiquitin-like protein ligase activity
0.47	GO:0003677	DNA binding

0.77	GO:0031965	nuclear membrane
0.68	GO:0016605	PML body
0.65	GO:0030424	axon
0.48	GO:0005737	cytoplasm

0.72

GO:0004842

sp|Q9Y253|POLH_HUMAN
DNA polymerase eta
Search

POLH

0.83	DNA-directed DNA polymerase eta

0.65	GO:0006281	DNA repair
0.63	GO:0071494	cellular response to UV-C
0.50	GO:0071897	DNA biosynthetic process
0.36	GO:0006282	regulation of DNA repair
0.36	GO:0006260	DNA replication
0.34	GO:0016567	protein ubiquitination
0.33	GO:0006508	proteolysis

0.72	GO:0003684	damaged DNA binding
0.52	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0004252	serine-type endopeptidase activity

0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.52	EC:2.7.7.7	GO:0003887
0.34	KEGG:R03876	GO:0004842

sp|Q9Y255|PRLD1_HUMAN
PRELI domain-containing protein 1, mitochondrial
Search

PRELID1

0.96	PRELI domain-containing protein 1, mitochondrial

0.57	GO:0010917	negative regulation of mitochondrial membrane potential
0.56	GO:1901857	positive regulation of cellular respiration
0.56	GO:2001140	positive regulation of phospholipid transport
0.56	GO:0070234	positive regulation of T cell apoptotic process
0.56	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.53	GO:0045580	regulation of T cell differentiation
0.53	GO:0010950	positive regulation of endopeptidase activity
0.53	GO:0015914	phospholipid transport
0.51	GO:0097035	regulation of membrane lipid distribution
0.38	GO:0006915	apoptotic process

0.59	GO:1990050	phosphatidic acid transporter activity
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.79	GO:0005758	mitochondrial intermembrane space
0.47	GO:0005654	nucleoplasm
0.43	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.34

GO:0018024

sp|Q9Y256|FACE2_HUMAN
CAAX prenyl protease 2
Search

RCE1

0.96	Ras converting CAAX endopeptidase 1

0.72

GO:0071586

CAAX-box protein processing

0.58	GO:0004175	endopeptidase activity
0.49	GO:0008234	cysteine-type peptidase activity
0.47	GO:0008237	metallopeptidase activity

0.64	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0008234

sp|Q9Y257|KCNK6_HUMAN
Potassium channel subfamily K member 6
Search

0.95	Potassium two pore domain channel subfamily K member 6

0.72	GO:0071805	potassium ion transmembrane transport
0.68	GO:0060075	regulation of resting membrane potential
0.59	GO:0003085	negative regulation of systemic arterial blood pressure
0.53	GO:0030322	stabilization of membrane potential
0.47	GO:0035725	sodium ion transmembrane transport
0.42	GO:0003015	heart process
0.38	GO:0035094	response to nicotine
0.37	GO:0061337	cardiac conduction
0.35	GO:0034765	regulation of ion transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.76	GO:0005267	potassium channel activity
0.59	GO:0022842	narrow pore channel activity
0.49	GO:0005272	sodium channel activity
0.49	GO:0099094	ligand-gated cation channel activity
0.47	GO:0022843	voltage-gated cation channel activity
0.46	GO:0042802	identical protein binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.52	GO:1902937	inward rectifier potassium channel complex
0.47	GO:0005768	endosome
0.40	GO:0043204	perikaryon
0.40	GO:0016324	apical plasma membrane
0.39	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0030425	dendrite
0.38	GO:0045202	synapse
0.38	GO:0030054	cell junction
0.38	GO:0031526	brush border membrane

0.34

GO:0016705

sp|Q9Y258|CCL26_HUMAN
C-C motif chemokine 26
Search

CCL26

0.65	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0010469	regulation of receptor activity
0.74	GO:0071674	mononuclear cell migration
0.74	GO:0006955	immune response
0.73	GO:0072676	lymphocyte migration
0.71	GO:0097529	myeloid leukocyte migration
0.70	GO:0070098	chemokine-mediated signaling pathway
0.67	GO:0001938	positive regulation of endothelial cell proliferation
0.66	GO:0050921	positive regulation of chemotaxis
0.64	GO:0043547	positive regulation of GTPase activity

0.84	GO:0008009	chemokine activity
0.74	GO:0048020	CCR chemokine receptor binding
0.38	GO:0016004	phospholipase activator activity
0.35	GO:0004672	protein kinase activity

0.72	GO:0005615	extracellular space
0.30	GO:0005623	cell

sp|Q9Y259|CHKB_HUMAN
Choline/ethanolamine kinase
Search

0.65	Choline kinase alpha

0.62	GO:0046474	glycerophospholipid biosynthetic process
0.58	GO:0046470	phosphatidylcholine metabolic process
0.57	GO:0016310	phosphorylation
0.54	GO:0046337	phosphatidylethanolamine metabolic process
0.47	GO:0007517	muscle organ development
0.43	GO:1901566	organonitrogen compound biosynthetic process
0.38	GO:1904681	response to 3-methylcholanthrene
0.36	GO:0006580	ethanolamine metabolic process
0.36	GO:0019695	choline metabolic process
0.35	GO:0009636	response to toxic substance

0.63	GO:0004103	choline kinase activity
0.59	GO:0004305	ethanolamine kinase activity
0.51	GO:0004104	cholinesterase activity
0.48	GO:0042803	protein homodimerization activity
0.41	GO:0008144	drug binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0033265	choline binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004871	signal transducer activity

0.36

GO:0005829

cytosol

0.63	EC:2.7.1.32	GO:0004103
0.63	KEGG:R01021	GO:0004103

sp|Q9Y261|FOXA2_HUMAN
Hepatocyte nuclear factor 3-beta
Search

FOXA2

0.95	Hepatocyte nuclear factor 3-alpha

0.61	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.59	GO:0071542	dopaminergic neuron differentiation
0.58	GO:0031018	endocrine pancreas development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1900046	regulation of hemostasis
0.57	GO:0050818	regulation of coagulation
0.56	GO:0061041	regulation of wound healing
0.56	GO:0010468	regulation of gene expression
0.55	GO:1902680	positive regulation of RNA biosynthetic process

0.76	GO:0019904	protein domain specific binding
0.72	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.36	GO:0046332	SMAD binding
0.35	GO:0019900	kinase binding

0.61	GO:0005634	nucleus
0.52	GO:0030054	cell junction
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.41	GO:0005902	microvillus
0.38	GO:0005700	polytene chromosome
0.34	GO:0005737	cytoplasm

sp|Q9Y262|EIF3L_HUMAN
Eukaryotic translation initiation factor 3 subunit L
Search

EIF3L

0.71	Eukaryotic translation initiation factor 3 subunit L

0.72	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.54	GO:0075525	viral translational termination-reinitiation
0.38	GO:0032456	endocytic recycling

0.71	GO:0003743	translation initiation factor activity
0.37	GO:0017137	Rab GTPase binding
0.34	GO:0046872	metal ion binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.71	GO:0033290	eukaryotic 48S preinitiation complex
0.51	GO:0001650	fibrillar center
0.46	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q9Y263|PLAP_HUMAN
Phospholipase A-2-activating protein
Search

PLAA

0.90	phospholipase A-2-activating protein isoform X1

0.86	GO:0032430	positive regulation of phospholipase A2 activity
0.86	GO:1900045	negative regulation of protein K63-linked ubiquitination
0.86	GO:1903423	positive regulation of synaptic vesicle recycling
0.85	GO:2001224	positive regulation of neuron migration
0.85	GO:1903861	positive regulation of dendrite extension
0.83	GO:0006692	prostanoid metabolic process
0.81	GO:0071222	cellular response to lipopolysaccharide
0.81	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.78	GO:0016236	macroautophagy
0.76	GO:0006954	inflammatory response

0.86	GO:0016005	phospholipase A2 activator activity
0.64	GO:0043130	ubiquitin binding
0.39	GO:0016905	myosin heavy chain kinase activity

0.78	GO:0070062	extracellular exosome
0.72	GO:0045202	synapse
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.48	GO:0030054	cell junction

0.39

EC:2.7.11.7

GO:0016905

sp|Q9Y264|ANGP4_HUMAN
Angiopoietin-4
Search

ANGPT4

0.83	Angiopoietin-4

0.80	GO:0001525	angiogenesis
0.70	GO:0048014	Tie signaling pathway
0.65	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.62	GO:0043535	regulation of blood vessel endothelial cell migration
0.61	GO:0010595	positive regulation of endothelial cell migration
0.60	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.57	GO:0051241	negative regulation of multicellular organismal process
0.57	GO:0043066	negative regulation of apoptotic process
0.55	GO:0071456	cellular response to hypoxia
0.55	GO:0030336	negative regulation of cell migration

0.85	GO:0030971	receptor tyrosine kinase binding
0.58	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.36	GO:0005172	vascular endothelial growth factor receptor binding
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.55	GO:0005615	extracellular space
0.49	GO:0005902	microvillus
0.47	GO:0098857	membrane microdomain
0.39	GO:0005886	plasma membrane
0.34	GO:1903561	extracellular vesicle
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9Y265|RUVB1_HUMAN
RuvB-like 1
Search

RUVBL1

0.66	RuvB-like helicase

0.70	GO:0032392	DNA geometric change
0.63	GO:0006281	DNA repair
0.62	GO:0006310	DNA recombination
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.55	GO:0016569	covalent chromatin modification
0.55	GO:1903146	regulation of autophagy of mitochondrion

0.81	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.56	GO:0001094	TFIID-class transcription factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0051117	ATPase binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0045296	cadherin binding

0.83	GO:0097255	R2TP complex
0.79	GO:0035267	NuA4 histone acetyltransferase complex
0.79	GO:0031011	Ino80 complex
0.57	GO:0000812	Swr1 complex
0.53	GO:0071339	MLL1 complex
0.47	GO:0005829	cytosol
0.43	GO:0030529	intracellular ribonucleoprotein complex

0.81

EC:3.6.1

GO:0043141

sp|Q9Y266|NUDC_HUMAN
Nuclear migration protein nudC
Search

NUDC

0.90	Nuclear migration protein nudC

0.57	GO:0032502	developmental process
0.53	GO:0060271	cilium assembly
0.52	GO:0006457	protein folding
0.49	GO:0032501	multicellular organismal process
0.42	GO:0051301	cell division
0.42	GO:0007049	cell cycle
0.38	GO:0007097	nuclear migration
0.38	GO:0043434	response to peptide hormone
0.38	GO:0008283	cell proliferation
0.37	GO:0007059	chromosome segregation

0.71	GO:0045296	cadherin binding
0.53	GO:0051082	unfolded protein binding

0.61	GO:0005829	cytosol
0.44	GO:0005874	microtubule
0.39	GO:0005634	nucleus
0.36	GO:0005794	Golgi apparatus
0.36	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|Q9Y267|S22AE_HUMAN
Solute carrier family 22 member 14
Search

SLC22A14

0.86	Solute carrier family 22 (organic cation transporter), member 14

0.56	GO:0043252	sodium-independent organic anion transport
0.55	GO:0055085	transmembrane transport
0.47	GO:0015698	inorganic anion transport
0.41	GO:2001142	nicotinate transport
0.40	GO:0015747	urate transport
0.38	GO:0015695	organic cation transport
0.38	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.36	GO:0023014	signal transduction by protein phosphorylation
0.36	GO:0008643	carbohydrate transport
0.33	GO:0005975	carbohydrate metabolic process

0.56	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.53	GO:0005452	inorganic anion exchanger activity
0.41	GO:0090416	nicotinate transmembrane transporter activity
0.38	GO:0015101	organic cation transmembrane transporter activity
0.38	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.37	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.34	GO:0015143	urate transmembrane transporter activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005887	integral component of plasma membrane
0.37	GO:0016324	apical plasma membrane
0.35	GO:0070062	extracellular exosome

0.38

GO:0004675

sp|Q9Y271|CLTR1_HUMAN
Cysteinyl leukotriene receptor 1
Search

CYSLTR1

0.97	Cysteinyl leukotriene receptor

0.81	GO:0061737	leukotriene signaling pathway
0.59	GO:0002437	inflammatory response to antigenic stimulus
0.53	GO:0006816	calcium ion transport
0.53	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.51	GO:0007166	cell surface receptor signaling pathway
0.50	GO:0006935	chemotaxis
0.49	GO:0007218	neuropeptide signaling pathway
0.47	GO:0003013	circulatory system process
0.41	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.39	GO:0035025	positive regulation of Rho protein signal transduction

0.81	GO:0004974	leukotriene receptor activity
0.49	GO:0008528	G-protein coupled peptide receptor activity
0.39	GO:0070915	lysophosphatidic acid receptor activity
0.37	GO:1990239	steroid hormone binding
0.36	GO:0030284	estrogen receptor activity
0.35	GO:0003682	chromatin binding
0.35	GO:0005515	protein binding
0.33	GO:0001608	G-protein coupled nucleotide receptor activity
0.33	GO:0001614	purinergic nucleotide receptor activity
0.33	GO:0016520	growth hormone-releasing hormone receptor activity

0.51	GO:0005887	integral component of plasma membrane
0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0045095	keratin filament
0.36	GO:0055037	recycling endosome
0.36	GO:0005769	early endosome
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0031984	organelle subcompartment
0.34	GO:0031967	organelle envelope

sp|Q9Y272|RASD1_HUMAN
Dexamethasone-induced Ras-related protein 1
Search

RASD1

0.96	RAS, dexamethasone-induced 1

0.61	GO:0007165	signal transduction
0.39	GO:0045892	negative regulation of transcription, DNA-templated

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005515	protein binding

0.48	GO:0016529	sarcoplasmic reticulum
0.40	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane

sp|Q9Y274|SIA10_HUMAN
Type 2 lactosamine alpha-2,3-sialyltransferase
Search

ST3GAL6

0.96	Type 2 lactosamine alpha-2,3-sialyltransferase

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process
0.51	GO:0071354	cellular response to interleukin-6
0.47	GO:0009311	oligosaccharide metabolic process
0.45	GO:0006664	glycolipid metabolic process
0.37	GO:0018146	keratan sulfate biosynthetic process
0.33	GO:0030148	sphingolipid biosynthetic process

0.83	GO:0008373	sialyltransferase activity
0.35	GO:0004308	exo-alpha-sialidase activity

0.69	GO:0005794	Golgi apparatus
0.44	GO:0098588	bounding membrane of organelle
0.43	GO:0031984	organelle subcompartment
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.99

GO:0008373

sp|Q9Y275|TN13B_HUMAN
Tumor necrosis factor ligand superfamily member 13B
Search

TNFSF13B

0.94	TNF family B-cell-activating factor

0.71	GO:0006955	immune response
0.61	GO:0031296	B cell costimulation
0.60	GO:0002636	positive regulation of germinal center formation
0.60	GO:0030890	positive regulation of B cell proliferation
0.60	GO:0048305	immunoglobulin secretion
0.58	GO:0031295	T cell costimulation
0.58	GO:0001782	B cell homeostasis
0.56	GO:0042102	positive regulation of T cell proliferation
0.37	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.37	GO:0010469	regulation of receptor activity

0.80	GO:0005164	tumor necrosis factor receptor binding
0.38	GO:0005125	cytokine activity

0.55	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y276|BCS1_HUMAN
Mitochondrial chaperone BCS1
Search

BCS1L

0.78	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

0.84	GO:0017062	respiratory chain complex III assembly
0.84	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.81	GO:0033108	mitochondrial respiratory chain complex assembly
0.56	GO:0097031	mitochondrial respiratory chain complex I biogenesis
0.56	GO:0010257	NADH dehydrogenase complex assembly
0.55	GO:0097034	mitochondrial respiratory chain complex IV biogenesis
0.55	GO:0008535	respiratory chain complex IV assembly
0.33	GO:0055114	oxidation-reduction process

0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding
0.33	GO:0005515	protein binding

0.61	GO:0005739	mitochondrion
0.36	GO:0019866	organelle inner membrane
0.34	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.34

GO:0016705

sp|Q9Y277|VDAC3_HUMAN
Voltage-dependent anion-selective channel protein 3
Search

VDAC3

0.95	Voltage-dependent anion-selective channel protein 3

0.85	GO:1902017	regulation of cilium assembly
0.69	GO:0098656	anion transmembrane transport
0.51	GO:0001662	behavioral fear response
0.51	GO:0007270	neuron-neuron synaptic transmission
0.49	GO:0007612	learning
0.39	GO:0031101	fin regeneration
0.36	GO:0015853	adenine transport

0.78	GO:0008308	voltage-gated anion channel activity
0.40	GO:0015288	porin activity
0.35	GO:1901265	nucleoside phosphate binding
0.35	GO:0036094	small molecule binding

0.78	GO:0005741	mitochondrial outer membrane
0.41	GO:0019866	organelle inner membrane
0.40	GO:0046930	pore complex
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.35	GO:0012505	endomembrane system
0.34	GO:0098793	presynapse
0.34	GO:0005634	nucleus

sp|Q9Y278|HS3S2_HUMAN
Heparan sulfate glucosamine 3-O-sulfotransferase 2
Search

HS3ST2

0.56	Sulfotransferase

0.78

GO:0008146

sulfotransferase activity

0.30

GO:0044425

membrane part

0.78

GO:0008146

sp|Q9Y279|VSIG4_HUMAN
V-set and immunoglobulin domain-containing protein 4
Search

VSIG4

0.97	V-set and immunoglobulin domain-containing protein 4

0.45	GO:0006957	complement activation, alternative pathway
0.38	GO:0032703	negative regulation of interleukin-2 production
0.38	GO:0042130	negative regulation of T cell proliferation

0.38

GO:0005515

protein binding

0.44	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q9Y281|COF2_HUMAN
Cofilin-2
Search

CFL2

0.96	Cofilin 2 homolog (Predicted)

0.84	GO:0030042	actin filament depolymerization
0.59	GO:0030836	positive regulation of actin filament depolymerization
0.55	GO:0046716	muscle cell cellular homeostasis
0.54	GO:0045214	sarcomere organization
0.53	GO:0007519	skeletal muscle tissue development
0.46	GO:0001842	neural fold formation
0.44	GO:0001755	neural crest cell migration
0.44	GO:0043200	response to amino acid
0.44	GO:0044794	positive regulation by host of viral process
0.43	GO:0061001	regulation of dendritic spine morphogenesis

0.74	GO:0003779	actin binding
0.54	GO:0032403	protein complex binding
0.41	GO:0005102	receptor binding
0.37	GO:0019903	protein phosphatase binding
0.37	GO:1902936	phosphatidylinositol bisphosphate binding
0.35	GO:0046872	metal ion binding

0.74	GO:0015629	actin cytoskeleton
0.54	GO:0030018	Z disc
0.45	GO:0030027	lamellipodium
0.45	GO:0016363	nuclear matrix
0.43	GO:0030863	cortical cytoskeleton
0.42	GO:0005615	extracellular space
0.42	GO:0005911	cell-cell junction
0.40	GO:0032587	ruffle membrane
0.40	GO:0044430	cytoskeletal part
0.38	GO:1903561	extracellular vesicle

sp|Q9Y282|ERGI3_HUMAN
Endoplasmic reticulum-Golgi intermediate compartment protein 3
Search

ERGIC3

0.92	ERGIC and golgi 3

0.30

GO:0044425

membrane part

sp|Q9Y283|INVS_HUMAN
Inversin
Search

INVS

0.62

Inversin

0.82	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.48	GO:0016055	Wnt signaling pathway
0.46	GO:0007275	multicellular organism development
0.40	GO:0060429	epithelium development

0.48

GO:0005516

calmodulin binding

0.45	GO:0005856	cytoskeleton
0.43	GO:0097543	ciliary inversin compartment
0.42	GO:0097546	ciliary base
0.41	GO:0099512	supramolecular fiber
0.38	GO:0005634	nucleus
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q9Y284|ASTER_HUMAN
Protein Asterix
Search

WDR83OS

0.97	WD repeat domain 83 opposite strand

0.37	GO:0006013	mannose metabolic process
0.35	GO:0008033	tRNA processing
0.34	GO:0006915	apoptotic process
0.34	GO:0042981	regulation of apoptotic process
0.34	GO:0006517	protein deglycosylation
0.33	GO:0006508	proteolysis

0.37	GO:0004559	alpha-mannosidase activity
0.35	GO:0030246	carbohydrate binding
0.34	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

0.37

EC:3.2.1.24

GO:0004559

sp|Q9Y285|SYFA_HUMAN
Phenylalanine--tRNA ligase alpha subunit
Search

FARSA

0.44	Phenylalanyl-tRNA synthetase alpha subunit

0.75	GO:0006432	phenylalanyl-tRNA aminoacylation
0.57	GO:0051290	protein heterotetramerization
0.38	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.75	GO:0004826	phenylalanine-tRNA ligase activity
0.69	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0002161	aminoacyl-tRNA editing activity
0.33	GO:0005515	protein binding

0.60	GO:0009328	phenylalanine-tRNA ligase complex
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.75

EC:6.1.1.20

GO:0004826

sp|Q9Y286|SIGL7_HUMAN
Sialic acid-binding Ig-like lectin 7
Search

0.93	Sialic acid binding Ig like lectin 7

0.45	GO:0007155	cell adhesion
0.41	GO:0050776	regulation of immune response
0.40	GO:0043312	neutrophil degranulation
0.38	GO:0023052	signaling
0.38	GO:0007154	cell communication
0.37	GO:0051716	cellular response to stimulus
0.35	GO:0050794	regulation of cellular process

0.58	GO:0030246	carbohydrate binding
0.39	GO:0004872	receptor activity
0.37	GO:0005515	protein binding
0.36	GO:0004871	signal transducer activity

0.41	GO:0005887	integral component of plasma membrane
0.39	GO:0030667	secretory granule membrane
0.35	GO:0005576	extracellular region

sp|Q9Y287|ITM2B_HUMAN
Integral membrane protein 2B
Search

ITM2B

0.97	Integral membrane protein 2B

0.63	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process
0.45	GO:0007399	nervous system development
0.39	GO:0006915	apoptotic process
0.39	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.38	GO:0008285	negative regulation of cell proliferation
0.37	GO:0038034	signal transduction in absence of ligand
0.37	GO:0002317	plasma cell differentiation
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0002377	immunoglobulin production

0.60	GO:0001540	amyloid-beta binding
0.42	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008134	transcription factor binding

0.54	GO:0030660	Golgi-associated vesicle membrane
0.53	GO:0031301	integral component of organelle membrane
0.53	GO:0005615	extracellular space
0.52	GO:0005794	Golgi apparatus
0.48	GO:1903561	extracellular vesicle
0.44	GO:0005886	plasma membrane
0.42	GO:0010008	endosome membrane
0.40	GO:0031984	organelle subcompartment
0.39	GO:0035189	Rb-E2F complex

sp|Q9Y289|SC5A6_HUMAN
Sodium-dependent multivitamin transporter
Search

SLC5A6

0.91	Sodium-dependent multivitamin transporter

0.55	GO:0055085	transmembrane transport
0.38	GO:0015878	biotin transport
0.38	GO:0006814	sodium ion transport
0.38	GO:0072337	modified amino acid transport
0.35	GO:0006768	biotin metabolic process
0.35	GO:0015939	pantothenate metabolic process

0.57

GO:0022857

transmembrane transporter activity

0.39	GO:0031526	brush border membrane
0.38	GO:0012506	vesicle membrane
0.34	GO:0005887	integral component of plasma membrane

sp|Q9Y291|RT33_HUMAN
28S ribosomal protein S33, mitochondrial
Search

MRPS33

0.94	Mitochondrial ribosomal protein S33

0.37	GO:0070126	mitochondrial translational termination
0.36	GO:0070125	mitochondrial translational elongation

0.35

GO:0003735

structural constituent of ribosome

0.56	GO:0005840	ribosome
0.48	GO:0005739	mitochondrion
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.30	GO:0016021	integral component of membrane

sp|Q9Y294|ASF1A_HUMAN
Histone chaperone ASF1A
Search

ASF1A

0.90	Anti-silencing function 1Ba histone chaperone

0.76	GO:0006333	chromatin assembly or disassembly
0.61	GO:0034728	nucleosome organization
0.60	GO:0065004	protein-DNA complex assembly
0.59	GO:0001649	osteoblast differentiation
0.59	GO:0006323	DNA packaging
0.57	GO:0042692	muscle cell differentiation
0.48	GO:0006281	DNA repair
0.45	GO:0016569	covalent chromatin modification
0.38	GO:0032986	protein-DNA complex disassembly
0.38	GO:0006351	transcription, DNA-templated

0.62	GO:0042393	histone binding
0.55	GO:0003682	chromatin binding

0.60	GO:0005634	nucleus
0.56	GO:0000785	chromatin
0.53	GO:0031974	membrane-enclosed lumen
0.48	GO:0043234	protein complex

sp|Q9Y295|DRG1_HUMAN
Developmentally-regulated GTP-binding protein 1
Search

DRG1

0.89	Developmentally regulated GTP binding protein 1

0.33	GO:0007275	multicellular organism development
0.33	GO:0006351	transcription, DNA-templated

0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042802	identical protein binding
0.34	GO:0008134	transcription factor binding

0.52	GO:0005844	polysome
0.50	GO:0016604	nuclear body
0.46	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y296|TPPC4_HUMAN
Trafficking protein particle complex subunit 4
Search

TRAPPC4

0.92	Trafficking protein particle complex subunit 4

0.69	GO:0016192	vesicle-mediated transport
0.53	GO:0016358	dendrite development
0.43	GO:0046907	intracellular transport
0.43	GO:0065009	regulation of molecular function
0.36	GO:0045212	neurotransmitter receptor biosynthetic process
0.35	GO:0051650	establishment of vesicle localization
0.34	GO:0016050	vesicle organization
0.34	GO:0006461	protein complex assembly
0.34	GO:0042176	regulation of protein catabolic process
0.33	GO:0061024	membrane organization

0.49	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0030234	enzyme regulator activity

0.81	GO:0030008	TRAPP complex
0.52	GO:0008021	synaptic vesicle
0.52	GO:0030425	dendrite
0.51	GO:0005795	Golgi stack
0.38	GO:0005783	endoplasmic reticulum
0.34	GO:0045211	postsynaptic membrane
0.34	GO:0030054	cell junction
0.34	GO:0000139	Golgi membrane
0.34	GO:0005829	cytosol
0.33	GO:1905369	endopeptidase complex

0.33

GO:0004222

sp|Q9Y297|FBW1A_HUMAN
F-box/WD repeat-containing protein 1A
Search

BTRC

0.93	Beta-transducin repeat containing

0.56	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.56	GO:0042753	positive regulation of circadian rhythm
0.55	GO:0031648	protein destabilization
0.54	GO:0033598	mammary gland epithelial cell proliferation
0.54	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.54	GO:0000209	protein polyubiquitination
0.53	GO:0060444	branching involved in mammary gland duct morphogenesis
0.52	GO:0060828	regulation of canonical Wnt signaling pathway
0.52	GO:0045862	positive regulation of proteolysis
0.51	GO:0061136	regulation of proteasomal protein catabolic process

0.68	GO:0046983	protein dimerization activity
0.53	GO:0045309	protein phosphorylated amino acid binding
0.53	GO:0008013	beta-catenin binding
0.51	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0016874	ligase activity

0.54	GO:0019005	SCF ubiquitin ligase complex
0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.38	GO:0005813	centrosome
0.33	GO:0043233	organelle lumen

0.33

GO:0016874

sp|Q9Y2A0|T53G1_HUMAN
TP53-target gene 1 protein
Search

sp|Q9Y2A4|ZN443_HUMAN
Zinc finger protein 443
Search

0.65	Zinc finger protein 799

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.41	GO:0006351	transcription, DNA-templated
0.36	GO:0007165	signal transduction

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.35	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space

0.40

EC:3.1.4.17

GO:0004114

sp|Q9Y2A7|NCKP1_HUMAN
Nck-associated protein 1
Search

NCKAP1

0.95	NCK-associated protein 1

0.73	GO:0016601	Rac protein signal transduction
0.73	GO:0010592	positive regulation of lamellipodium assembly
0.71	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation
0.57	GO:0045175	basal protein localization
0.56	GO:0048617	embryonic foregut morphogenesis
0.56	GO:0048340	paraxial mesoderm morphogenesis
0.55	GO:0007354	zygotic determination of anterior/posterior axis, embryo
0.55	GO:0048570	notochord morphogenesis
0.55	GO:0008078	mesodermal cell migration
0.55	GO:0045176	apical protein localization

0.71	GO:0048365	Rac GTPase binding
0.62	GO:0032403	protein complex binding

0.71	GO:0031209	SCAR complex
0.70	GO:0031258	lamellipodium membrane
0.59	GO:0031941	filamentous actin
0.57	GO:0001726	ruffle
0.52	GO:0005925	focal adhesion
0.52	GO:0070062	extracellular exosome
0.42	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q9Y2A9|B3GN3_HUMAN
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
Search

B3GNT3

0.55	Hexosyltransferase

0.74	GO:0006486	protein glycosylation
0.55	GO:0030311	poly-N-acetyllactosamine biosynthetic process

0.80	GO:0008378	galactosyltransferase activity
0.55	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0008378

sp|Q9Y2B0|CNPY2_HUMAN
Protein canopy homolog 2
Search

CNPY2

0.37	Canopy FGF signaling regulator 2

0.85	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process
0.82	GO:0010988	regulation of low-density lipoprotein particle clearance
0.63	GO:0010629	negative regulation of gene expression
0.59	GO:0007167	enzyme linked receptor protein signaling pathway
0.58	GO:0009888	tissue development
0.43	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.41	GO:0006099	tricarboxylic acid cycle
0.41	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.40	GO:0006401	RNA catabolic process
0.39	GO:0006397	mRNA processing

0.46	GO:0004108	citrate (Si)-synthase activity
0.43	GO:0004535	poly(A)-specific ribonuclease activity
0.36	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity

0.56	GO:0005783	endoplasmic reticulum
0.43	GO:0031251	PAN complex
0.42	GO:0000932	P-body
0.37	GO:0005759	mitochondrial matrix
0.37	GO:0005634	nucleus
0.36	GO:0005887	integral component of plasma membrane

0.46

EC:2.3.3.1

GO:0004108

sp|Q9Y2B1|TMEM5_HUMAN
Transmembrane protein 5
Search

TMEM5

0.97	Transmembrane protein 5

0.59	GO:0035269	protein O-linked mannosylation
0.34	GO:0051028	mRNA transport
0.34	GO:0008380	RNA splicing
0.34	GO:0006397	mRNA processing

0.64	GO:0120053	ribitol beta-1,4-xylosyltransferase activity
0.34	GO:0003729	mRNA binding

0.51	GO:0005794	Golgi apparatus
0.50	GO:0005654	nucleoplasm
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.34	GO:0005887	integral component of plasma membrane

sp|Q9Y2B2|PIGL_HUMAN
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
Search

PIGL

0.87	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

0.51	GO:0006506	GPI anchor biosynthetic process
0.35	GO:0000956	nuclear-transcribed mRNA catabolic process
0.35	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0007165	signal transduction

0.58	GO:0000225	N-acetylglucosaminylphosphatidylinositol deacetylase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.58

EC:3.5.1.89

GO:0000225

sp|Q9Y2B4|T53G5_HUMAN
TP53-target gene 5 protein
Search

0.66	GO:0030308	negative regulation of cell growth
0.52	GO:0035556	intracellular signal transduction
0.51	GO:0010951	negative regulation of endopeptidase activity

0.52

GO:0004867

serine-type endopeptidase inhibitor activity

0.55	GO:0005634	nucleus
0.46	GO:0005576	extracellular region
0.42	GO:0005737	cytoplasm

sp|Q9Y2B5|VP9D1_HUMAN
VPS9 domain-containing protein 1
Search

VPS9D1

0.96	VPS9 domain-containing protein 1

0.58	GO:0043547	positive regulation of GTPase activity
0.55	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.55	GO:0006754	ATP biosynthetic process

0.58	GO:0005096	GTPase activator activity
0.46	GO:0005215	transporter activity

0.30

GO:0016020

membrane

sp|Q9Y2B9|IPKG_HUMAN
cAMP-dependent protein kinase inhibitor gamma
Search

PKIG

0.93	cAMP-dependent protein kinase inhibitor gamma

0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.64	GO:0042308	negative regulation of protein import into nucleus
0.59	GO:0000122	negative regulation of transcription by RNA polymerase II
0.54	GO:2000479	regulation of cAMP-dependent protein kinase activity
0.50	GO:0016310	phosphorylation
0.40	GO:1904355	positive regulation of telomere capping
0.40	GO:0051973	positive regulation of telomerase activity
0.39	GO:0032212	positive regulation of telomere maintenance via telomerase
0.39	GO:0007165	signal transduction

0.86	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.52	GO:0016301	kinase activity
0.35	GO:0005515	protein binding

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|Q9Y2C2|UST_HUMAN
Uronyl 2-sulfotransferase
Search

UST

0.97	Uronyl 2-sulfotransferase

0.58	GO:0050770	regulation of axonogenesis
0.58	GO:0030010	establishment of cell polarity
0.37	GO:0030208	dermatan sulfate biosynthetic process
0.36	GO:0006477	protein sulfation
0.31	GO:0006351	transcription, DNA-templated
0.31	GO:1903506	regulation of nucleic acid-templated transcription
0.31	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.31	GO:0010468	regulation of gene expression

0.78	GO:0008146	sulfotransferase activity
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.37	GO:0000139	Golgi membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.78

GO:0008146

sp|Q9Y2C3|B3GT5_HUMAN
Beta-1,3-galactosyltransferase 5
Search

B3GALT5

0.54	Beta-1,3-galactosyltransferase 5

0.74

GO:0006486

protein glycosylation

0.81	GO:0008378	galactosyltransferase activity
0.48	GO:0008194	UDP-glycosyltransferase activity

0.70	GO:0005794	Golgi apparatus
0.65	GO:0098588	bounding membrane of organelle
0.63	GO:0031984	organelle subcompartment
0.47	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008378

sp|Q9Y2C4|EXOG_HUMAN
Nuclease EXOG, mitochondrial
Search

EXOG

0.97	Exo/endonuclease G

0.60

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.71	GO:0008409	5'-3' exonuclease activity
0.62	GO:0004519	endonuclease activity
0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.58	GO:0031966	mitochondrial membrane
0.58	GO:0019866	organelle inner membrane
0.56	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q9Y2C5|S17A4_HUMAN
Probable small intestine urate exporter
Search

0.97	Sodium-dependent phosphate transport protein 3

0.58	GO:0015747	urate transport
0.56	GO:0035435	phosphate ion transmembrane transport
0.54	GO:0046415	urate metabolic process
0.53	GO:0035725	sodium ion transmembrane transport
0.47	GO:1901998	toxin transport
0.45	GO:0006855	drug transmembrane transport
0.34	GO:0015712	hexose phosphate transport
0.34	GO:0007601	visual perception
0.34	GO:0007268	chemical synaptic transmission
0.34	GO:0044341	sodium-dependent phosphate transport

0.59	GO:0005436	sodium:phosphate symporter activity
0.51	GO:0015143	urate transmembrane transporter activity
0.48	GO:0019534	toxin transmembrane transporter activity
0.46	GO:0008308	voltage-gated anion channel activity
0.45	GO:0015562	efflux transmembrane transporter activity
0.44	GO:0015238	drug transmembrane transporter activity
0.34	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.33	GO:0015172	acidic amino acid transmembrane transporter activity
0.33	GO:0015179	L-amino acid transmembrane transporter activity
0.33	GO:0005310	dicarboxylic acid transmembrane transporter activity

0.54	GO:0016324	apical plasma membrane
0.50	GO:0005887	integral component of plasma membrane
0.47	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031526	brush border membrane
0.33	GO:0030672	synaptic vesicle membrane

sp|Q9Y2C9|TLR6_HUMAN
Toll-like receptor 6
Search

TLR6

0.92	Toll like receptor 6

0.86	GO:0070340	detection of bacterial lipopeptide
0.83	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.82	GO:0050707	regulation of cytokine secretion
0.81	GO:0045410	positive regulation of interleukin-6 biosynthetic process
0.80	GO:0006954	inflammatory response
0.80	GO:0034150	toll-like receptor 6 signaling pathway
0.79	GO:0071724	response to diacyl bacterial lipopeptide
0.78	GO:0045087	innate immune response
0.78	GO:0042088	T-helper 1 type immune response
0.65	GO:0034130	toll-like receptor 1 signaling pathway

0.70	GO:0004888	transmembrane signaling receptor activity
0.56	GO:0035663	Toll-like receptor 2 binding
0.47	GO:0046982	protein heterodimerization activity
0.47	GO:0071723	lipopeptide binding
0.45	GO:0042802	identical protein binding

0.50	GO:0098857	membrane microdomain
0.50	GO:0043235	receptor complex
0.47	GO:0005794	Golgi apparatus
0.41	GO:0044459	plasma membrane part
0.40	GO:0030670	phagocytic vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y2D0|CAH5B_HUMAN
Carbonic anhydrase 5B, mitochondrial
Search

CA5B

0.97	Carbonic anhydrase VB, mitochondrial

0.71	GO:0006730	one-carbon metabolic process
0.44	GO:2000021	regulation of ion homeostasis
0.42	GO:2001225	regulation of chloride transport
0.42	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.41	GO:0051453	regulation of intracellular pH
0.41	GO:0032846	positive regulation of homeostatic process
0.37	GO:0015701	bicarbonate transport
0.33	GO:0019319	hexose biosynthetic process
0.33	GO:0006006	glucose metabolic process
0.32	GO:0043043	peptide biosynthetic process

0.77	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding
0.32	GO:0003735	structural constituent of ribosome

0.58	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:4.2.1.1

GO:0004089

sp|Q9Y2D1|ATF5_HUMAN
Cyclic AMP-dependent transcription factor ATF-5
Search

ATF5

0.94	Cyclic AMP-dependent transcription factor ATF-5

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.66	GO:0045444	fat cell differentiation
0.65	GO:0046605	regulation of centrosome cycle
0.65	GO:0021891	olfactory bulb interneuron development
0.65	GO:0021924	cell proliferation in external granule layer
0.64	GO:1902750	negative regulation of cell cycle G2/M phase transition
0.62	GO:0043066	negative regulation of apoptotic process
0.61	GO:0008285	negative regulation of cell proliferation
0.60	GO:0035264	multicellular organism growth
0.59	GO:0007623	circadian rhythm

0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0003682	chromatin binding
0.61	GO:0019900	kinase binding
0.60	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.58	GO:0015631	tubulin binding
0.39	GO:0003714	transcription corepressor activity
0.38	GO:0031072	heat shock protein binding

0.61	GO:0005813	centrosome
0.56	GO:0005654	nucleoplasm
0.55	GO:0005667	transcription factor complex
0.55	GO:0005829	cytosol

sp|Q9Y2D2|S35A3_HUMAN
UDP-N-acetylglucosamine transporter
Search

SLC35A3

0.91	UDP-N-acetylglucosamine transporter

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.56	GO:1990569	UDP-N-acetylglucosamine transmembrane transport
0.34	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0005351	sugar:proton symporter activity
0.35	GO:0005462	UDP-N-acetylglucosamine transmembrane transporter activity
0.33	GO:0005515	protein binding

0.74	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y2D4|EXC6B_HUMAN
Exocyst complex component 6B
Search

EXOC6B

0.77	Exocyst complex component

0.79	GO:0006904	vesicle docking involved in exocytosis
0.34	GO:0015031	protein transport
0.34	GO:0055114	oxidation-reduction process

0.37	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.36	GO:0020037	heme binding
0.36	GO:0005506	iron ion binding
0.34	GO:0005515	protein binding

0.78	GO:0000145	exocyst
0.35	GO:0090543	Flemming body
0.34	GO:0030426	growth cone
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016705

sp|Q9Y2D5|AKAP2_HUMAN
A-kinase anchor protein 2
Search

AKAP2

0.88	A-kinase anchor protein 2

0.57	GO:0016310	phosphorylation
0.47	GO:0008360	regulation of cell shape
0.39	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.38	GO:0007015	actin filament organization
0.38	GO:0051291	protein heterooligomerization
0.36	GO:0008104	protein localization

0.60	GO:0016301	kinase activity
0.39	GO:0051018	protein kinase A binding
0.36	GO:0019904	protein domain specific binding

0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q9Y2D8|ADIP_HUMAN
Afadin- and alpha-actinin-binding protein
Search

SSX2IP

0.96	Afadin-and alpha-actinin-binding protein isoform 1

0.84	GO:0035020	regulation of Rac protein signal transduction
0.83	GO:0035735	intraciliary transport involved in cilium assembly
0.79	GO:0007098	centrosome cycle
0.73	GO:2000145	regulation of cell motility
0.47	GO:0007368	determination of left/right symmetry
0.45	GO:0007155	cell adhesion
0.38	GO:0006869	lipid transport
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0030036	actin cytoskeleton organization

0.44	GO:0019904	protein domain specific binding
0.40	GO:0051011	microtubule minus-end binding
0.38	GO:0030674	protein binding, bridging
0.38	GO:0005319	lipid transporter activity
0.36	GO:0004871	signal transducer activity

0.84	GO:0034451	centriolar satellite
0.81	GO:0036064	ciliary basal body
0.75	GO:0031252	cell leading edge
0.57	GO:0043234	protein complex
0.48	GO:0005912	adherens junction
0.44	GO:0005911	cell-cell junction
0.39	GO:1905360	GTPase complex
0.39	GO:0005634	nucleus
0.39	GO:0005874	microtubule
0.39	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

sp|Q9Y2D9|ZN652_HUMAN
Zinc finger protein 652
Search

ZNF652

0.55	LOW QUALITY PROTEIN: zinc finger protein 652

0.36	GO:0097659	nucleic acid-templated transcription
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.49	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.37

GO:0005634

nucleus

sp|Q9Y2E4|DIP2C_HUMAN
Disco-interacting protein 2 homolog C
Search

DIP2C

0.93	Disco-interacting protein 2 like protein C

0.30

GO:0008152

metabolic process

0.30

GO:0003824

catalytic activity

sp|Q9Y2E5|MA2B2_HUMAN
Epididymis-specific alpha-mannosidase
Search

MAN2B2

0.47	Epididymis-specific alpha-mannosidase

0.81	GO:0006013	mannose metabolic process
0.50	GO:0006517	protein deglycosylation
0.35	GO:0009313	oligosaccharide catabolic process

0.79	GO:0004559	alpha-mannosidase activity
0.69	GO:0030246	carbohydrate binding
0.52	GO:0046872	metal ion binding

0.43	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.38	GO:0005764	lysosome
0.36	GO:0005775	vacuolar lumen
0.30	GO:0044425	membrane part

0.79

EC:3.2.1.24

GO:0004559

sp|Q9Y2E6|DTX4_HUMAN
E3 ubiquitin-protein ligase DTX4
Search

DTX4

0.95	Deltex E3 ubiquitin ligase 4

0.38	GO:0007219	Notch signaling pathway
0.36	GO:0016567	protein ubiquitination
0.36	GO:0032479	regulation of type I interferon production

0.59	GO:0008270	zinc ion binding
0.46	GO:0016874	ligase activity
0.35	GO:0004842	ubiquitin-protein transferase activity

0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.46	EC:6	GO:0016874
0.35	KEGG:R03876	GO:0004842

sp|Q9Y2E8|SL9A8_HUMAN
Sodium/hydrogen exchanger 8
Search

SLC9A8

0.61	Sodium/hydrogen exchanger

0.77	GO:0006885	regulation of pH
0.75	GO:0035725	sodium ion transmembrane transport
0.61	GO:1902600	hydrogen ion transmembrane transport
0.56	GO:0030004	cellular monovalent inorganic cation homeostasis
0.52	GO:0071805	potassium ion transmembrane transport
0.50	GO:0099587	inorganic ion import across plasma membrane

0.80	GO:0015385	sodium:proton antiporter activity
0.58	GO:0015386	potassium:proton antiporter activity

0.51	GO:0005794	Golgi apparatus
0.39	GO:0005886	plasma membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2F5|ICE1_HUMAN
Little elongation complex subunit 1
Search

ICE1

0.97	Interactor of little elongation complex ELL subunit 1

0.87	GO:0042796	snRNA transcription by RNA polymerase III
0.86	GO:0042795	snRNA transcription by RNA polymerase II
0.86	GO:0045945	positive regulation of transcription by RNA polymerase III
0.84	GO:0090316	positive regulation of intracellular protein transport
0.79	GO:0031334	positive regulation of protein complex assembly

0.43

GO:0042803

protein homodimerization activity

0.86	GO:0035363	histone locus body
0.85	GO:0015030	Cajal body
0.85	GO:0035327	transcriptionally active chromatin
0.79	GO:0008023	transcription elongation factor complex

sp|Q9Y2F9|BTBD3_HUMAN
BTB/POZ domain-containing protein 3
Search

BTBD3

0.89	BTB/POZ domain-containing protein 3

0.85	GO:0021987	cerebral cortex development
0.85	GO:0048813	dendrite morphogenesis
0.67	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.64	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.61	GO:0030162	regulation of proteolysis

0.65

GO:0031625

ubiquitin protein ligase binding

0.69	GO:0005829	cytosol
0.68	GO:0019005	SCF ubiquitin ligase complex
0.61	GO:0005634	nucleus

sp|Q9Y2G0|EFR3B_HUMAN
Protein EFR3 homolog B
Search

EFR3BB

0.95	EFR3 homolog Bb (S. cerevisiae)

0.83	GO:0072659	protein localization to plasma membrane
0.74	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0098609	cell-cell adhesion

0.39

GO:0005515

protein binding

0.56	GO:0005886	plasma membrane
0.44	GO:0005829	cytosol

sp|Q9Y2G1|MRF_HUMAN
Myelin regulatory factor
Search

MYRF

0.90	Myelin gene regulatory factor

0.63	GO:0032286	central nervous system myelin maintenance
0.62	GO:0031643	positive regulation of myelination
0.57	GO:0006355	regulation of transcription, DNA-templated
0.53	GO:1903508	positive regulation of nucleic acid-templated transcription
0.52	GO:0010628	positive regulation of gene expression
0.35	GO:0006508	proteolysis
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0006281	DNA repair
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.39	GO:0042802	identical protein binding
0.36	GO:0008233	peptidase activity
0.33	GO:0004518	nuclease activity

0.52	GO:0005794	Golgi apparatus
0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.37	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0008233

sp|Q9Y2G2|CARD8_HUMAN
Caspase recruitment domain-containing protein 8
Search

CARD8

0.97	Caspase recruitment domain-containing protein 8

0.74	GO:0042981	regulation of apoptotic process
0.57	GO:0050713	negative regulation of interleukin-1 beta secretion
0.56	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.56	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.56	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.56	GO:0050718	positive regulation of interleukin-1 beta secretion
0.54	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.54	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.53	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.51	GO:0043068	positive regulation of programmed cell death

0.60	GO:0032089	NACHT domain binding
0.56	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.56	GO:0050700	CARD domain binding
0.49	GO:0042803	protein homodimerization activity

0.60	GO:0072559	NLRP3 inflammasome complex
0.47	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2G3|AT11B_HUMAN
Probable phospholipid-transporting ATPase IF
Search

ATP11B

0.60	Phospholipid-transporting ATPase

0.80	GO:0045332	phospholipid translocation
0.37	GO:0015917	aminophospholipid transport
0.37	GO:0043312	neutrophil degranulation
0.34	GO:0034220	ion transmembrane transport

0.81	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0015075	ion transmembrane transporter activity

0.61	GO:0055037	recycling endosome
0.52	GO:0005783	endoplasmic reticulum
0.39	GO:0005886	plasma membrane
0.39	GO:0005637	nuclear inner membrane
0.38	GO:0005769	early endosome
0.38	GO:0010008	endosome membrane
0.37	GO:0035577	azurophil granule membrane
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.81

EC:3.6.3.1

GO:0004012

sp|Q9Y2G4|ANKR6_HUMAN
Ankyrin repeat domain-containing protein 6
Search

ANKRD6

0.96	Ankyrin repeat domain-containing protein 6

0.85	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway
0.83	GO:0030178	negative regulation of Wnt signaling pathway
0.79	GO:0060828	regulation of canonical Wnt signaling pathway
0.65	GO:0046330	positive regulation of JNK cascade
0.52	GO:0048264	determination of ventral identity
0.51	GO:0001702	gastrulation with mouth forming second
0.50	GO:0042074	cell migration involved in gastrulation
0.48	GO:0007507	heart development
0.33	GO:0043666	regulation of phosphoprotein phosphatase activity
0.32	GO:0007165	signal transduction

0.42	GO:0008013	beta-catenin binding
0.33	GO:0019888	protein phosphatase regulator activity

0.59	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.37	GO:0043234	protein complex
0.33	GO:0000159	protein phosphatase type 2A complex

sp|Q9Y2G5|OFUT2_HUMAN
GDP-fucose protein O-fucosyltransferase 2
Search

POFUT2

0.93	GDP-fucose protein O-fucosyltransferase 2

0.76	GO:0006004	fucose metabolic process
0.62	GO:0036066	protein O-linked fucosylation
0.55	GO:0001707	mesoderm formation
0.55	GO:0010717	regulation of epithelial to mesenchymal transition
0.54	GO:0051046	regulation of secretion
0.42	GO:0060255	regulation of macromolecule metabolic process
0.33	GO:0007017	microtubule-based process
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0006364	rRNA processing
0.32	GO:0006508	proteolysis

0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.45	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005794	Golgi apparatus
0.37	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0016757

sp|Q9Y2G7|ZFP30_HUMAN
Zinc finger protein 30 homolog
Search

ZNF383

0.71	Zinc finger protein 14

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0003700	DNA binding transcription factor activity

0.47	GO:0031965	nuclear membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2G8|DJC16_HUMAN
DnaJ homolog subfamily C member 16
Search

DNAJC16

0.86	DnaJ like protein subfamily C member 16

0.67	GO:0045454	cell redox homeostasis
0.33	GO:0006508	proteolysis

0.34

GO:0004252

serine-type endopeptidase activity

0.43	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.34

GO:0004252

sp|Q9Y2G9|SBNO2_HUMAN
Protein strawberry notch homolog 2
Search

SBNO2

0.96	Strawberry notch homolog 2

0.81	GO:0050727	regulation of inflammatory response
0.60	GO:0071348	cellular response to interleukin-11
0.58	GO:0002281	macrophage activation involved in immune response
0.58	GO:0072675	osteoclast fusion
0.58	GO:0061430	bone trabecula morphogenesis
0.57	GO:0071354	cellular response to interleukin-6
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0030282	bone mineralization

0.34	GO:0005515	protein binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0003677	DNA binding

0.32

GO:0005634

nucleus

0.33

GO:0003899

sp|Q9Y2H0|DLGP4_HUMAN
Disks large-associated protein 4
Search

DLGAP4

0.92	DLG associated protein 4

0.60	GO:0023052	signaling
0.47	GO:0006461	protein complex assembly

0.50

GO:0019904

protein domain specific binding

0.62

GO:0045202

synapse

sp|Q9Y2H1|ST38L_HUMAN
Serine/threonine-protein kinase 38-like
Search

STK38L

0.93	Serine/threonine-protein kinase 38

0.63	GO:0006468	protein phosphorylation
0.49	GO:0018209	peptidyl-serine modification
0.49	GO:0035556	intracellular signal transduction
0.48	GO:0043407	negative regulation of MAP kinase activity
0.44	GO:0051128	regulation of cellular component organization
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.48	GO:0000287	magnesium ion binding
0.47	GO:0045296	cadherin binding
0.35	GO:0003779	actin binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0003735	structural constituent of ribosome

0.50	GO:0005829	cytosol
0.48	GO:0015629	actin cytoskeleton
0.41	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.70

GO:0004674

sp|Q9Y2H2|SAC2_HUMAN
Phosphatidylinositide phosphatase SAC2
Search

INPP5F

0.91	Inositol polyphosphate-5-phosphatase F

0.77	GO:0031161	phosphatidylinositol catabolic process
0.75	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.75	GO:0001921	positive regulation of receptor recycling
0.74	GO:2001135	regulation of endocytic recycling
0.73	GO:0003299	muscle hypertrophy in response to stress
0.73	GO:0014887	cardiac muscle adaptation
0.73	GO:0003300	cardiac muscle hypertrophy
0.73	GO:0048681	negative regulation of axon regeneration
0.69	GO:0008344	adult locomotory behavior
0.67	GO:0046856	phosphatidylinositol dephosphorylation

0.73	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity
0.72	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.66	GO:0052833	inositol monophosphate 4-phosphatase activity
0.63	GO:0042803	protein homodimerization activity

0.70	GO:0045334	clathrin-coated endocytic vesicle
0.69	GO:0055037	recycling endosome
0.67	GO:0005905	clathrin-coated pit
0.67	GO:0005769	early endosome
0.67	GO:0043025	neuronal cell body
0.67	GO:0030425	dendrite
0.66	GO:0030424	axon

0.66

EC:3.1.3.25

GO:0052833

sp|Q9Y2H5|PKHA6_HUMAN
Pleckstrin homology domain-containing family A member 6
Search

PLEKHA6

0.90	Pleckstrin homology domain-containing family A member 6

0.57	GO:0016192	vesicle-mediated transport
0.44	GO:0006508	proteolysis
0.43	GO:0061458	reproductive system development

0.48	GO:0070001	aspartic-type peptidase activity
0.46	GO:0010314	phosphatidylinositol-5-phosphate binding
0.46	GO:0004175	endopeptidase activity
0.45	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.45	GO:0070273	phosphatidylinositol-4-phosphate binding
0.45	GO:0032266	phosphatidylinositol-3-phosphate binding
0.39	GO:0005515	protein binding

0.41	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2H6|FND3A_HUMAN
Fibronectin type-III domain-containing protein 3A
Search

FNDC3A

0.95	Fibronectin type-III domain-containing protein 3A

0.51	GO:0060009	Sertoli cell development
0.49	GO:0007286	spermatid development
0.49	GO:0009566	fertilization
0.47	GO:0098609	cell-cell adhesion

0.34	GO:0003723	RNA binding
0.30	GO:0003824	catalytic activity

0.50	GO:0005794	Golgi apparatus
0.49	GO:0001669	acrosomal vesicle
0.46	GO:0012506	vesicle membrane
0.44	GO:0005829	cytosol
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2H8|ZN510_HUMAN
Zinc finger protein 510
Search

0.64	Zinc finger protein 12

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.44	GO:0043392	negative regulation of DNA binding
0.44	GO:1902679	negative regulation of RNA biosynthetic process
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:0060669	embryonic placenta morphogenesis
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process

0.52	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0043228	non-membrane-bounded organelle
0.36	GO:0044422	organelle part
0.33	GO:1990904	ribonucleoprotein complex

sp|Q9Y2H9|MAST1_HUMAN
Microtubule-associated serine/threonine-protein kinase 1
Search

0.89	LOW QUALITY PROTEIN: microtubule-associated serine/threonine-protein kinase 1

0.64	GO:0007010	cytoskeleton organization
0.64	GO:0045075	regulation of interleukin-12 biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.57	GO:0035556	intracellular signal transduction
0.48	GO:0018209	peptidyl-serine modification
0.36	GO:0048515	spermatid differentiation
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.70	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0019902	phosphatase binding
0.38	GO:0008017	microtubule binding
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005622	intracellular
0.37	GO:0043228	non-membrane-bounded organelle
0.35	GO:0005886	plasma membrane
0.34	GO:0030054	cell junction
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

sp|Q9Y2I1|NISCH_HUMAN
Nischarin
Search

NISCH

0.79

Nischarin

0.69	GO:0016601	Rac protein signal transduction
0.64	GO:0030336	negative regulation of cell migration
0.58	GO:0030036	actin cytoskeleton organization
0.44	GO:0048243	norepinephrine secretion
0.41	GO:0032228	regulation of synaptic transmission, GABAergic
0.40	GO:0008217	regulation of blood pressure
0.39	GO:0006915	apoptotic process
0.38	GO:0006006	glucose metabolic process
0.31	GO:0007155	cell adhesion

0.83	GO:0005178	integrin binding
0.76	GO:0035091	phosphatidylinositol binding
0.58	GO:0042802	identical protein binding
0.34	GO:0046872	metal ion binding
0.32	GO:0005540	hyaluronic acid binding

0.55	GO:0005829	cytosol
0.47	GO:0005886	plasma membrane
0.40	GO:0055037	recycling endosome
0.40	GO:0005769	early endosome

sp|Q9Y2I2|NTNG1_HUMAN
Netrin-G1
Search

0.78	Vav 3 guanine nucleotide exchange factor b

0.77	GO:0007409	axonogenesis
0.44	GO:0006501	C-terminal protein lipidation

0.41

GO:0005515

protein binding

0.79	GO:0046658	anchored component of plasma membrane
0.39	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q9Y2I6|NINL_HUMAN
Ninein-like protein
Search

NINL

0.94	Ninein like

0.43	GO:0097711	ciliary basal body-plasma membrane docking
0.42	GO:0000086	G2/M transition of mitotic cell cycle
0.41	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.37	GO:0035845	photoreceptor cell outer segment organization
0.37	GO:0042462	eye photoreceptor cell development
0.33	GO:0001696	gastric acid secretion
0.33	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.32	GO:0007062	sister chromatid cohesion
0.32	GO:0030261	chromosome condensation
0.31	GO:0006260	DNA replication

0.70	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding
0.33	GO:0016907	G-protein coupled acetylcholine receptor activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0003677	DNA binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0045171	intercellular bridge
0.55	GO:0005829	cytosol
0.43	GO:0005815	microtubule organizing center
0.41	GO:0005874	microtubule
0.36	GO:0044441	ciliary part
0.33	GO:0045211	postsynaptic membrane
0.32	GO:0030054	cell junction
0.32	GO:0005887	integral component of plasma membrane
0.31	GO:0005694	chromosome

sp|Q9Y2I7|FYV1_HUMAN
1-phosphatidylinositol 3-phosphate 5-kinase
Search

PIKFYVE

0.88	Phosphoinositide kinase, FYVE-type zinc finger containing

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.60	GO:2000785	regulation of autophagosome assembly
0.57	GO:0032288	myelin assembly
0.57	GO:0042147	retrograde transport, endosome to Golgi
0.55	GO:0034504	protein localization to nucleus
0.46	GO:0006458	'de novo' protein folding
0.45	GO:0061077	chaperone-mediated protein folding
0.37	GO:1904562	phosphatidylinositol 5-phosphate metabolic process
0.36	GO:0006898	receptor-mediated endocytosis

0.85	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.56	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.48	GO:0044183	protein binding involved in protein folding
0.43	GO:0051082	unfolded protein binding
0.37	GO:0052810	1-phosphatidylinositol-5-kinase activity
0.36	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

0.58	GO:0031901	early endosome membrane
0.55	GO:0045121	membrane raft
0.54	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005911	cell-cell junction
0.51	GO:0012506	vesicle membrane
0.50	GO:0005829	cytosol
0.38	GO:0032593	insulin-responsive compartment
0.37	GO:0031902	late endosome membrane
0.36	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.1.150	GO:0000285
0.85	KEGG:R05802	GO:0000285

sp|Q9Y2I8|WDR37_HUMAN
WD repeat-containing protein 37
Search

WDR37

0.94	WD repeat-containing protein 37

0.82	GO:0000470	maturation of LSU-rRNA
0.81	GO:0000460	maturation of 5.8S rRNA

0.85	GO:0070545	PeBoW complex
0.81	GO:0030687	preribosome, large subunit precursor

sp|Q9Y2I9|TBC30_HUMAN
TBC1 domain family member 30
Search

TBC1D30

0.95	TBC1 domain family member 30 isoform C

0.85	GO:1902018	negative regulation of cilium assembly
0.75	GO:0043547	positive regulation of GTPase activity
0.68	GO:0031338	regulation of vesicle fusion
0.57	GO:0006886	intracellular protein transport

0.80	GO:0017137	Rab GTPase binding
0.75	GO:0005096	GTPase activator activity

0.77	GO:0036064	ciliary basal body
0.65	GO:0005829	cytosol
0.56	GO:0012505	endomembrane system
0.53	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2J0|RP3A_HUMAN
Rabphilin-3A
Search

RPH3A

0.97

Rabphilin

0.69	GO:0006886	intracellular protein transport
0.51	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.50	GO:0017158	regulation of calcium ion-dependent exocytosis
0.49	GO:0006906	vesicle fusion
0.35	GO:0046879	hormone secretion
0.35	GO:0007420	brain development

0.77	GO:0017137	Rab GTPase binding
0.52	GO:0046872	metal ion binding
0.49	GO:0019905	syntaxin binding
0.49	GO:0005544	calcium-dependent phospholipid binding
0.48	GO:0030276	clathrin binding
0.39	GO:0070679	inositol 1,4,5 trisphosphate binding
0.39	GO:0008430	selenium binding
0.39	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0032403	protein complex binding
0.38	GO:0042301	phosphate ion binding

0.49	GO:0070382	exocytic vesicle
0.48	GO:0098793	presynapse
0.40	GO:0030141	secretory granule
0.39	GO:0005886	plasma membrane
0.39	GO:0030054	cell junction
0.38	GO:0030658	transport vesicle membrane
0.38	GO:0043005	neuron projection
0.38	GO:0019898	extrinsic component of membrane
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005829	cytosol

sp|Q9Y2J2|E41L3_HUMAN
Band 4.1-like protein 3
Search

EPB41L3

0.88	Erythrocyte membrane protein band 4.1 like 3

0.85	GO:0007016	cytoskeletal anchoring at plasma membrane
0.81	GO:0030866	cortical actin cytoskeleton organization
0.80	GO:0001558	regulation of cell growth
0.65	GO:0002175	protein localization to paranode region of axon
0.63	GO:0030913	paranodal junction assembly
0.63	GO:0071205	protein localization to juxtaparanode region of axon
0.63	GO:0043217	myelin maintenance
0.59	GO:0072659	protein localization to plasma membrane
0.57	GO:0048812	neuron projection morphogenesis
0.52	GO:0008360	regulation of cell shape

0.72	GO:0003779	actin binding
0.61	GO:0005198	structural molecule activity

0.77	GO:0005911	cell-cell junction
0.69	GO:0005856	cytoskeleton
0.64	GO:0044224	juxtaparanode region of axon
0.63	GO:0033270	paranode region of axon
0.62	GO:0030673	axolemma
0.60	GO:0014069	postsynaptic density
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2J4|AMOL2_HUMAN
Angiomotin-like protein 2
Search

AMOTL2

0.84	To angiomotin like 2

0.52	GO:0035329	hippo signaling
0.48	GO:0016055	Wnt signaling pathway
0.44	GO:0003365	establishment of cell polarity involved in ameboidal cell migration
0.43	GO:0035912	dorsal aorta morphogenesis
0.43	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.41	GO:0046847	filopodium assembly
0.41	GO:0001935	endothelial cell proliferation
0.41	GO:0060026	convergent extension
0.40	GO:0009880	embryonic pattern specification
0.40	GO:0030866	cortical actin cytoskeleton organization

0.72

GO:0042802

identical protein binding

0.80	GO:0016324	apical plasma membrane
0.79	GO:0005923	bicellular tight junction
0.71	GO:0031410	cytoplasmic vesicle
0.44	GO:0012505	endomembrane system
0.42	GO:0030027	lamellipodium
0.41	GO:0008180	COP9 signalosome
0.39	GO:0005938	cell cortex
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2J8|PADI2_HUMAN
Protein-arginine deiminase type-2
Search

PADI2

0.66	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

0.82	GO:0018101	protein citrullination
0.61	GO:0010848	regulation of chromatin disassembly
0.60	GO:1901624	negative regulation of lymphocyte chemotaxis
0.60	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.58	GO:0048096	chromatin-mediated maintenance of transcription
0.58	GO:0030520	intracellular estrogen receptor signaling pathway
0.56	GO:1990823	response to leukemia inhibitory factor
0.54	GO:0016570	histone modification
0.53	GO:0071345	cellular response to cytokine stimulus
0.41	GO:0032501	multicellular organismal process

0.81	GO:0004668	protein-arginine deiminase activity
0.70	GO:0005509	calcium ion binding
0.57	GO:0030331	estrogen receptor binding
0.40	GO:0016990	arginine deiminase activity
0.38	GO:0034618	arginine binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0051538	3 iron, 4 sulfur cluster binding
0.34	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.34	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0051539	4 iron, 4 sulfur cluster binding

0.56	GO:0035327	transcriptionally active chromatin
0.49	GO:0005737	cytoplasm
0.43	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0070062	extracellular exosome
0.36	GO:0031983	vesicle lumen
0.35	GO:0043234	protein complex
0.34	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.33	GO:0019866	organelle inner membrane

0.81	EC:3.5.3.15	GO:0004668
0.34	KEGG:R02164	GO:0008177

sp|Q9Y2K1|ZBTB1_HUMAN
Zinc finger and BTB domain-containing protein 1
Search

ZBTB1

0.97	LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 1

0.64	GO:2000174	regulation of pro-T cell differentiation
0.64	GO:1905458	positive regulation of lymphoid progenitor cell differentiation
0.62	GO:0032825	positive regulation of natural killer cell differentiation
0.60	GO:0042789	mRNA transcription by RNA polymerase II
0.60	GO:0002711	positive regulation of T cell mediated immunity
0.59	GO:0033077	T cell differentiation in thymus
0.59	GO:0048538	thymus development
0.59	GO:0045582	positive regulation of T cell differentiation
0.59	GO:0030183	B cell differentiation
0.58	GO:0034644	cellular response to UV

0.60	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.53	GO:0042803	protein homodimerization activity
0.53	GO:0046982	protein heterodimerization activity
0.51	GO:0003676	nucleic acid binding
0.48	GO:0046872	metal ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.31	GO:0004842	ubiquitin-protein transferase activity

0.55	GO:0031965	nuclear membrane
0.55	GO:0016604	nuclear body
0.32	GO:0031463	Cul3-RING ubiquitin ligase complex

0.31

GO:0004842

sp|Q9Y2K2|SIK3_HUMAN
Serine/threonine-protein kinase SIK3
Search

SIK3

0.76	SIK family kinase 3

0.63	GO:0006468	protein phosphorylation
0.38	GO:0001958	endochondral ossification
0.38	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.38	GO:0035264	multicellular organism growth
0.38	GO:0035108	limb morphogenesis
0.36	GO:0032880	regulation of protein localization
0.34	GO:0035556	intracellular signal transduction

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0000287	magnesium ion binding

0.54	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm

sp|Q9Y2K3|MYH15_HUMAN
Myosin-15
Search

MYH15

0.76	Myosin heavy chain

0.74	GO:0007018	microtubule-based movement
0.41	GO:0061061	muscle structure development
0.39	GO:0014706	striated muscle tissue development
0.38	GO:0043010	camera-type eye development
0.37	GO:0048468	cell development
0.35	GO:0031449	regulation of slow-twitch skeletal muscle fiber contraction
0.35	GO:0014728	regulation of the force of skeletal muscle contraction
0.35	GO:0030049	muscle filament sliding
0.35	GO:0014883	transition between fast and slow fiber
0.35	GO:0007512	adult heart development

0.76	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005516	calmodulin binding
0.35	GO:0030898	actin-dependent ATPase activity
0.35	GO:0000146	microfilament motor activity

0.77	GO:0016459	myosin complex
0.51	GO:0097512	cardiac myofibril
0.37	GO:0030017	sarcomere
0.35	GO:0097517	contractile actin filament bundle
0.34	GO:0042641	actomyosin
0.30	GO:0016020	membrane

sp|Q9Y2K5|R3HD2_HUMAN
R3H domain-containing protein 2
Search

R3HDM2

0.93	LOW QUALITY PROTEIN: R3H domain-containing protein 2

0.37

GO:0035556

intracellular signal transduction

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.37

GO:0005634

nucleus

sp|Q9Y2K6|UBP20_HUMAN
Ubiquitin carboxyl-terminal hydrolase 20
Search

USP20

0.56	Ubiquitinyl hydrolase 1

0.75	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.54	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.36	GO:0032092	positive regulation of protein binding
0.36	GO:0032091	negative regulation of protein binding
0.36	GO:0051298	centrosome duplication
0.35	GO:0007411	axon guidance
0.35	GO:0050821	protein stabilization
0.35	GO:0009267	cellular response to starvation
0.35	GO:0016477	cell migration

0.77	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.62	GO:0008270	zinc ion binding
0.53	GO:0001664	G-protein coupled receptor binding
0.50	GO:0004197	cysteine-type endopeptidase activity
0.36	GO:0017160	Ral GTPase binding

0.52	GO:0005813	centrosome
0.36	GO:0005776	autophagosome
0.36	GO:0005925	focal adhesion
0.35	GO:0044297	cell body
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005794	Golgi apparatus
0.34	GO:0005654	nucleoplasm

0.50

GO:0004197

sp|Q9Y2K7|KDM2A_HUMAN
Lysine-specific demethylase 2A
Search

KDM2A

0.89	Lysine-specific demethylase 2A

0.65	GO:0070544	histone H3-K36 demethylation
0.59	GO:0006303	double-strand break repair via nonhomologous end joining
0.54	GO:0032259	methylation
0.38	GO:0001843	neural tube closure
0.38	GO:0048562	embryonic organ morphogenesis
0.38	GO:0033184	positive regulation of histone ubiquitination
0.38	GO:0007389	pattern specification process
0.37	GO:0043066	negative regulation of apoptotic process
0.37	GO:0060563	neuroepithelial cell differentiation
0.37	GO:0035264	multicellular organism growth

0.65	GO:0051864	histone demethylase activity (H3-K36 specific)
0.62	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.54	GO:0008168	methyltransferase activity
0.34	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005694	chromosome
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.65

EC:1.14.11.27

GO:0051864

sp|Q9Y2K9|STB5L_HUMAN
Syntaxin-binding protein 5-like
Search

STXBP5L

0.95	Syntaxin binding protein 5 like

0.69	GO:0046676	negative regulation of insulin secretion
0.69	GO:0016192	vesicle-mediated transport
0.67	GO:0017157	regulation of exocytosis
0.65	GO:0050714	positive regulation of protein secretion
0.64	GO:0042593	glucose homeostasis
0.48	GO:0043547	positive regulation of GTPase activity

0.68	GO:0019905	syntaxin binding
0.50	GO:0017137	Rab GTPase binding
0.48	GO:0005096	GTPase activator activity

0.48	GO:0005886	plasma membrane
0.37	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9Y2L1|RRP44_HUMAN
Exosome complex exonuclease RRP44
Search

DIS3

0.93	DIS3 exosome endoribonuclease and 3'-5' exoribonuclease

0.65	GO:0071034	CUT catabolic process
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.59	GO:0016075	rRNA catabolic process
0.51	GO:0065009	regulation of molecular function
0.46	GO:0006364	rRNA processing
0.45	GO:0071027	nuclear RNA surveillance
0.43	GO:0051607	defense response to virus
0.43	GO:0000278	mitotic cell cycle
0.38	GO:0060255	regulation of macromolecule metabolic process
0.35	GO:0031329	regulation of cellular catabolic process

0.67	GO:0004527	exonuclease activity
0.57	GO:0004540	ribonuclease activity
0.57	GO:0005085	guanyl-nucleotide exchange factor activity
0.54	GO:0004519	endonuclease activity
0.35	GO:0003723	RNA binding

0.65	GO:0000176	nuclear exosome (RNase complex)
0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol
0.47	GO:0005652	nuclear lamina
0.39	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|Q9Y2L5|TPPC8_HUMAN
Trafficking protein particle complex subunit 8
Search

TRAPPC8

0.91	LOW QUALITY PROTEIN: trafficking protein particle complex subunit 8

0.79	GO:0007030	Golgi organization
0.66	GO:0034497	protein localization to phagophore assembly site
0.66	GO:0032258	protein localization by the Cvt pathway
0.66	GO:0030242	autophagy of peroxisome
0.65	GO:0044804	autophagy of nucleus
0.61	GO:0006888	ER to Golgi vesicle-mediated transport
0.37	GO:0065009	regulation of molecular function

0.40

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.82	GO:0030008	TRAPP complex
0.63	GO:0000407	phagophore assembly site
0.57	GO:0044431	Golgi apparatus part
0.57	GO:0031410	cytoplasmic vesicle
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q9Y2L6|FRM4B_HUMAN
FERM domain-containing protein 4B
Search

FRMD4B

0.94	LOW QUALITY PROTEIN: FERM domain-containing protein 4B

0.57	GO:0090162	establishment of epithelial cell polarity
0.33	GO:0006508	proteolysis

0.45	GO:0008092	cytoskeletal protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.67	GO:0005856	cytoskeleton
0.55	GO:0001726	ruffle
0.55	GO:0005923	bicellular tight junction
0.54	GO:0005912	adherens junction
0.39	GO:0005737	cytoplasm
0.37	GO:0044421	extracellular region part
0.30	GO:0044425	membrane part

0.33

GO:0004222

sp|Q9Y2L8|ZKSC5_HUMAN
Zinc finger protein with KRAB and SCAN domains 5
Search

0.10	Zinc finger protein with KRAB and SCAN domains 5

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0006351	transcription, DNA-templated
0.40	GO:0015074	DNA integration
0.36	GO:1902680	positive regulation of RNA biosynthetic process

0.60	GO:0003700	DNA binding transcription factor activity
0.48	GO:0003676	nucleic acid binding
0.47	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q9Y2L9|LRCH1_HUMAN
Leucine-rich repeat and calponin homology domain-containing protein 1
Search

LRCH1

0.97	Leucine-rich repeat and calponin like proteiny domain-containing protein 1

0.81	GO:2000405	negative regulation of T cell migration
0.80	GO:1990868	response to chemokine
0.77	GO:0034260	negative regulation of GTPase activity
0.69	GO:0071345	cellular response to cytokine stimulus
0.47	GO:0007165	signal transduction

0.37

GO:0005515

protein binding

0.45	GO:0005737	cytoplasm
0.44	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2M0|FAN1_HUMAN
Fanconi-associated nuclease 1
Search

FAN1

0.96	Fanconi anemia associated nuclease 1

0.81	GO:0036297	interstrand cross-link repair
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.56	GO:0000724	double-strand break repair via homologous recombination
0.53	GO:0006289	nucleotide-excision repair
0.34	GO:0006364	rRNA processing

0.64	GO:0070336	flap-structured DNA binding
0.64	GO:0140036	ubiquitin-dependent protein binding
0.63	GO:0004518	nuclease activity
0.48	GO:0140097	catalytic activity, acting on DNA
0.40	GO:0008081	phosphoric diester hydrolase activity
0.35	GO:0046872	metal ion binding

0.59	GO:0045171	intercellular bridge
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.36	GO:0034457	Mpp10 complex
0.36	GO:0005732	small nucleolar ribonucleoprotein complex

0.63

EC:3.1

GO:0004518

sp|Q9Y2M2|SSUH2_HUMAN
Protein SSUH2 homolog
Search

SSUH2

0.97	LOW QUALITY PROTEIN: protein SSUH2 homolog

0.70	GO:0042476	odontogenesis
0.32	GO:0022900	electron transport chain
0.32	GO:0009408	response to heat
0.32	GO:0006457	protein folding
0.32	GO:0006260	DNA replication

0.72	GO:0031072	heat shock protein binding
0.66	GO:0051082	unfolded protein binding
0.33	GO:0051537	2 iron, 2 sulfur cluster binding
0.32	GO:0009055	electron transfer activity
0.32	GO:0008270	zinc ion binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9Y2M5|KLH20_HUMAN
Kelch-like protein 20
Search

KLHL20

0.66	Kelch like family member 20

0.86	GO:1990390	protein K33-linked ubiquitination
0.80	GO:0006895	Golgi to endosome transport
0.72	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.69	GO:0035455	response to interferon-alpha
0.68	GO:0043066	negative regulation of apoptotic process
0.43	GO:0015031	protein transport
0.30	GO:0043687	post-translational protein modification
0.30	GO:0016043	cellular component organization

0.86	GO:0019964	interferon-gamma binding
0.69	GO:0004842	ubiquitin-protein transferase activity
0.30	GO:0008092	cytoskeletal protein binding

0.79	GO:0016605	PML body
0.77	GO:0031463	Cul3-RING ubiquitin ligase complex
0.74	GO:0005802	trans-Golgi network
0.64	GO:0005829	cytosol
0.47	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0097458	neuron part
0.30	GO:0043232	intracellular non-membrane-bounded organelle

0.69

GO:0004842

sp|Q9Y2N7|HIF3A_HUMAN
Hypoxia-inducible factor 3-alpha
Search

HIF3A

0.96	Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a

0.59	GO:0001666	response to hypoxia
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process
0.50	GO:0051541	elastin metabolic process
0.50	GO:0060574	intestinal epithelial cell maturation

0.66	GO:0046983	protein dimerization activity
0.55	GO:0003700	DNA binding transcription factor activity
0.51	GO:0035035	histone acetyltransferase binding
0.48	GO:0070888	E-box binding
0.47	GO:0051879	Hsp90 protein binding
0.47	GO:0042826	histone deacetylase binding
0.47	GO:0002039	p53 binding
0.46	GO:0035257	nuclear hormone receptor binding
0.46	GO:0000989	transcription factor activity, transcription factor binding
0.45	GO:0031625	ubiquitin protein ligase binding

0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.52	GO:0070013	intracellular organelle lumen
0.49	GO:0005667	transcription factor complex
0.48	GO:1904115	axon cytoplasm
0.46	GO:0044446	intracellular organelle part
0.45	GO:0031514	motile cilium
0.42	GO:0005886	plasma membrane
0.36	GO:0005739	mitochondrion

sp|Q9Y2P0|ZN835_HUMAN
Zinc finger protein 835
Search

0.64	Zinc finger protein 7

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.41	GO:0071294	cellular response to zinc ion
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0042254	ribosome biogenesis
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:1900112	regulation of histone H3-K9 trimethylation
0.32	GO:0006468	protein phosphorylation

0.49	GO:0003676	nucleic acid binding
0.48	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.37	GO:0042803	protein homodimerization activity
0.33	GO:0003682	chromatin binding
0.32	GO:0004672	protein kinase activity
0.31	GO:0005524	ATP binding

0.41	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.33	GO:0043233	organelle lumen
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0019013	viral nucleocapsid
0.31	GO:1990904	ribonucleoprotein complex

sp|Q9Y2P4|S27A6_HUMAN
Long-chain fatty acid transport protein 6
Search

SLC27A6

0.92	Solute carrier family 27 fatty acid transporter member 6

0.78	GO:0001676	long-chain fatty acid metabolic process
0.75	GO:0015908	fatty acid transport
0.45	GO:0097089	methyl-branched fatty acid metabolic process
0.45	GO:0001561	fatty acid alpha-oxidation
0.44	GO:0006699	bile acid biosynthetic process
0.43	GO:0042760	very long-chain fatty acid catabolic process
0.41	GO:0006635	fatty acid beta-oxidation

0.85	GO:0031957	very long-chain fatty acid-CoA ligase activity
0.78	GO:0004467	long-chain fatty acid-CoA ligase activity
0.46	GO:0070251	pristanate-CoA ligase activity
0.46	GO:0050197	phytanate-CoA ligase activity
0.43	GO:0015245	fatty acid transmembrane transporter activity
0.40	GO:0005102	receptor binding
0.40	GO:0019899	enzyme binding
0.35	GO:0004321	fatty-acyl-CoA synthase activity

0.47	GO:0005783	endoplasmic reticulum
0.42	GO:0005779	integral component of peroxisomal membrane
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.39	GO:0043233	organelle lumen
0.37	GO:0005739	mitochondrion

0.78	EC:6.2.1.3	GO:0004467
0.46	KEGG:R03631	GO:0050197

sp|Q9Y2P5|S27A5_HUMAN
Bile acyl-CoA synthetase
Search

SLC27A5

0.43	Acetoacetyl-CoA synthetase / Long-chain-fatty-acid--CoA ligase

0.76	GO:0006699	bile acid biosynthetic process
0.71	GO:0015908	fatty acid transport
0.70	GO:0001676	long-chain fatty acid metabolic process
0.60	GO:0000038	very long-chain fatty acid metabolic process
0.59	GO:0046951	ketone body biosynthetic process
0.59	GO:0006642	triglyceride mobilization
0.51	GO:1903825	organic acid transmembrane transport
0.49	GO:0098656	anion transmembrane transport
0.44	GO:0097089	methyl-branched fatty acid metabolic process
0.44	GO:0001561	fatty acid alpha-oxidation

0.77	GO:0031957	very long-chain fatty acid-CoA ligase activity
0.75	GO:0015245	fatty acid transmembrane transporter activity
0.71	GO:0004467	long-chain fatty acid-CoA ligase activity
0.45	GO:0047747	cholate-CoA ligase activity
0.45	GO:0070251	pristanate-CoA ligase activity
0.45	GO:0050197	phytanate-CoA ligase activity
0.40	GO:0005515	protein binding
0.38	GO:0044877	macromolecular complex binding
0.35	GO:0008144	drug binding
0.35	GO:0043168	anion binding

0.58	GO:0009925	basal plasma membrane
0.56	GO:0030176	integral component of endoplasmic reticulum membrane
0.42	GO:0005788	endoplasmic reticulum lumen
0.41	GO:0042579	microbody
0.41	GO:0031301	integral component of organelle membrane
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.37	GO:0005739	mitochondrion
0.36	GO:0043234	protein complex
0.36	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane

0.71	EC:6.2.1.3	GO:0004467
0.45	KEGG:R03631	GO:0050197

sp|Q9Y2P7|ZN256_HUMAN
Zinc finger protein 256
Search

0.74	Zinc finger protein 256

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0006351	transcription, DNA-templated
0.30	GO:0007275	multicellular organism development

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.30	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q9Y2P8|RCL1_HUMAN
RNA 3'-terminal phosphate cyclase-like protein
Search

RCL1

0.93	RNA terminal phosphate cyclase like 1

0.67	GO:0042254	ribosome biogenesis
0.63	GO:0006396	RNA processing
0.51	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.50	GO:0016072	rRNA metabolic process

0.50	GO:0003963	RNA-3'-phosphate cyclase activity
0.44	GO:0004521	endoribonuclease activity
0.35	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005730	nucleolus
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.50

EC:6.5.1.4

GO:0003963

sp|Q9Y2Q0|AT8A1_HUMAN
Phospholipid-transporting ATPase IA
Search

ATP8A1

0.59	Phospholipid-transporting ATPase IA

0.80	GO:0045332	phospholipid translocation
0.57	GO:0061092	positive regulation of phospholipid translocation
0.53	GO:0007612	learning
0.52	GO:0030335	positive regulation of cell migration
0.46	GO:0048194	Golgi vesicle budding
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0034220	ion transmembrane transport
0.32	GO:0065009	regulation of molecular function

0.81	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0019829	cation-transporting ATPase activity
0.33	GO:0098772	molecular function regulator

0.49	GO:0005794	Golgi apparatus
0.48	GO:0005783	endoplasmic reticulum
0.42	GO:0005886	plasma membrane
0.42	GO:0098588	bounding membrane of organelle
0.41	GO:0031984	organelle subcompartment
0.39	GO:0042583	chromaffin granule
0.37	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0098805	whole membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005766	primary lysosome

0.81

EC:3.6.3.1

GO:0004012

sp|Q9Y2Q1|ZN257_HUMAN
Zinc finger protein 257
Search

0.91	Zinc finger protein 85

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.41	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.40	GO:0043508	negative regulation of JUN kinase activity
0.40	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.40	GO:0045671	negative regulation of osteoclast differentiation
0.40	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.40	GO:0007249	I-kappaB kinase/NF-kappaB signaling

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0003700	DNA binding transcription factor activity
0.39	GO:0031625	ubiquitin protein ligase binding

0.45	GO:0005622	intracellular
0.42	GO:0043227	membrane-bounded organelle

sp|Q9Y2Q3|GSTK1_HUMAN
Glutathione S-transferase kappa 1
Search

GSTK1

0.82	Glutathione S-transferase kappa

0.52	GO:0055114	oxidation-reduction process
0.50	GO:0030855	epithelial cell differentiation
0.48	GO:0006749	glutathione metabolic process
0.47	GO:0098869	cellular oxidant detoxification
0.37	GO:1901687	glutathione derivative biosynthetic process
0.33	GO:0006468	protein phosphorylation

0.74	GO:0004364	glutathione transferase activity
0.71	GO:0015035	protein disulfide oxidoreductase activity
0.51	GO:0004602	glutathione peroxidase activity
0.47	GO:0005102	receptor binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005777	peroxisome
0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.37	GO:0005759	mitochondrial matrix
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.74

EC:2.5.1.18

GO:0004364

sp|Q9Y2Q5|LTOR2_HUMAN
Ragulator complex protein LAMTOR2
Search

LAMTOR2

0.97	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

0.81	GO:0032008	positive regulation of TOR signaling
0.66	GO:0065009	regulation of molecular function
0.58	GO:0071230	cellular response to amino acid stimulus
0.52	GO:0001558	regulation of cell growth
0.50	GO:0043410	positive regulation of MAPK cascade
0.47	GO:0034613	cellular protein localization
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0016241	regulation of macroautophagy
0.35	GO:0007050	cell cycle arrest
0.34	GO:0000165	MAPK cascade

0.81	GO:0032947	protein complex scaffold activity
0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.56	GO:0071986	Ragulator complex
0.43	GO:0005765	lysosomal membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:3.2.1

GO:0004553

sp|Q9Y2Q9|RT28_HUMAN
28S ribosomal protein S28, mitochondrial
Search

MRPS28

0.97	Mitochondrial ribosomal protein S28

0.38	GO:0070126	mitochondrial translational termination
0.38	GO:0070125	mitochondrial translational elongation
0.36	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.35	GO:0030183	B cell differentiation

0.36	GO:0003723	RNA binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0005509	calcium ion binding

0.58	GO:0005840	ribosome
0.49	GO:0005759	mitochondrial matrix
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2R0|COA3_HUMAN
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial
Search

COA3

0.72	Cytochrome oxidase assembly

0.67	GO:0070131	positive regulation of mitochondrial translation
0.65	GO:0033617	mitochondrial respiratory chain complex IV assembly

0.35

GO:0005515

protein binding

0.63

GO:0031305

integral component of mitochondrial inner membrane

sp|Q9Y2R2|PTN22_HUMAN
Tyrosine-protein phosphatase non-receptor type 22
Search

PTPN22

0.42	Tyrosine-protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.61	GO:0035644	phosphoanandamide dephosphorylation
0.60	GO:1902523	positive regulation of protein K63-linked ubiquitination
0.60	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
0.59	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation
0.59	GO:1903753	negative regulation of p38MAPK cascade
0.59	GO:0071225	cellular response to muramyl dipeptide
0.59	GO:0071663	positive regulation of granzyme B production
0.59	GO:2000483	negative regulation of interleukin-8 secretion
0.59	GO:1900165	negative regulation of interleukin-6 secretion

0.74	GO:0004725	protein tyrosine phosphatase activity
0.58	GO:0017124	SH3 domain binding
0.52	GO:0019900	kinase binding
0.39	GO:0031625	ubiquitin protein ligase binding

0.51	GO:0009898	cytoplasmic side of plasma membrane
0.49	GO:0002102	podosome
0.45	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.39	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005925	focal adhesion
0.34	GO:0042995	cell projection
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

0.74

GO:0004725

sp|Q9Y2R4|DDX52_HUMAN
Probable ATP-dependent RNA helicase DDX52
Search

DDX52

0.86	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52

0.51	GO:0010501	RNA secondary structure unwinding
0.45	GO:0006364	rRNA processing

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.49	GO:0004004	ATP-dependent RNA helicase activity

0.47	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q9Y2R5|RT17_HUMAN
28S ribosomal protein S17, mitochondrial
Search

MRPS17

0.93	Mitochondrial ribosomal protein S17

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0043624	cellular protein complex disassembly
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0019843	rRNA binding

0.61	GO:0005840	ribosome
0.45	GO:0005759	mitochondrial matrix
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane

sp|Q9Y2R9|RT07_HUMAN
28S ribosomal protein S7, mitochondrial
Search

MRPS7

0.93	Mitochondrial ribosomal protein S7

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:0000028	ribosomal small subunit assembly
0.34	GO:0043624	cellular protein complex disassembly

0.47	GO:0003735	structural constituent of ribosome
0.47	GO:0019843	rRNA binding
0.45	GO:0003729	mRNA binding
0.32	GO:0000049	tRNA binding
0.32	GO:0016787	hydrolase activity

0.56	GO:0005840	ribosome
0.52	GO:0005759	mitochondrial matrix
0.42	GO:0009536	plastid
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|Q9Y2S0|RPAC2_HUMAN
DNA-directed RNA polymerases I and III subunit RPAC2
Search

POLR1D

0.93	DNA-directed RNA polymerase I subunit D

0.58	GO:0006351	transcription, DNA-templated
0.41	GO:0006399	tRNA metabolic process
0.35	GO:0000183	chromatin silencing at rDNA
0.34	GO:0048703	embryonic viscerocranium morphogenesis
0.34	GO:0051216	cartilage development
0.33	GO:0042254	ribosome biogenesis
0.32	GO:0006508	proteolysis

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.68	GO:0046983	protein dimerization activity
0.54	GO:0003677	DNA binding
0.33	GO:0004197	cysteine-type endopeptidase activity

0.59	GO:0005736	DNA-directed RNA polymerase I complex
0.53	GO:0005666	DNA-directed RNA polymerase III complex

0.70

GO:0003899

sp|Q9Y2S2|CRYL1_HUMAN
Lambda-crystallin homolog
Search

CRYL1

0.74	Lambda-crystallin

0.69	GO:0006631	fatty acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0019640	glucuronate catabolic process to xylulose 5-phosphate

0.76	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.72	GO:0070403	NAD+ binding
0.61	GO:0050104	L-gulonate 3-dehydrogenase activity
0.50	GO:0042803	protein homodimerization activity
0.37	GO:0008080	N-acetyltransferase activity
0.35	GO:0005212	structural constituent of eye lens

0.39	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.76	EC:1.1.1.35	GO:0003857
0.61	KEGG:R02640	GO:0050104

sp|Q9Y2S6|TMA7_HUMAN
Translation machinery-associated protein 7
Search

TMA7

0.88	Translation machinery-associated protein 7

0.53	GO:0005975	carbohydrate metabolic process
0.46	GO:0000077	DNA damage checkpoint
0.40	GO:0006511	ubiquitin-dependent protein catabolic process
0.37	GO:0045332	phospholipid translocation
0.37	GO:0016192	vesicle-mediated transport

0.58	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.42	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0004012	phospholipid-translocating ATPase activity
0.36	GO:0003676	nucleic acid binding
0.35	GO:0000287	magnesium ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.58

EC:3.2.1

GO:0004553

sp|Q9Y2S7|PDIP2_HUMAN
Polymerase delta-interacting protein 2
Search

POLDIP2

0.95	DNA polymerase delta interacting protein 2

0.55	GO:0070584	mitochondrion morphogenesis
0.55	GO:0016242	negative regulation of macroautophagy
0.53	GO:0045931	positive regulation of mitotic cell cycle
0.34	GO:0006955	immune response
0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0042254	ribosome biogenesis

0.55	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0060090	molecular adaptor activity
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0001871	pattern binding
0.33	GO:0030246	carbohydrate binding

0.52	GO:0042645	mitochondrial nucleoid
0.36	GO:0005634	nucleus

sp|Q9Y2T1|AXIN2_HUMAN
Axin-2
Search

AXIN2

0.97	Axin 2 (conductin, axil)

0.77	GO:0016055	Wnt signaling pathway
0.71	GO:0032423	regulation of mismatch repair
0.71	GO:0070602	regulation of centromeric sister chromatid cohesion
0.69	GO:0035414	negative regulation of catenin import into nucleus
0.69	GO:0001957	intramembranous ossification
0.67	GO:0003139	secondary heart field specification
0.67	GO:0048255	mRNA stabilization
0.67	GO:0061181	regulation of chondrocyte development
0.67	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.67	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis

0.67	GO:0070411	I-SMAD binding
0.62	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0005096	GTPase activator activity
0.39	GO:0008013	beta-catenin binding
0.36	GO:0019901	protein kinase binding

0.61	GO:0005813	centrosome
0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.40	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q9Y2T2|AP3M1_HUMAN
AP-3 complex subunit mu-1
Search

AP3M1

0.89	LOW QUALITY PROTEIN: AP-3 complex subunit mu-1

0.68	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.62	GO:0008089	anterograde axonal transport
0.60	GO:0047496	vesicle transport along microtubule
0.59	GO:0097480	establishment of synaptic vesicle localization
0.35	GO:0061462	protein localization to lysosome
0.35	GO:0007041	lysosomal transport
0.35	GO:0072666	establishment of protein localization to vacuole
0.34	GO:0099643	signal release from synapse
0.34	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.54

GO:0017137

Rab GTPase binding

0.78	GO:0030131	clathrin adaptor complex
0.61	GO:1904115	axon cytoplasm
0.41	GO:0030659	cytoplasmic vesicle membrane
0.40	GO:0005794	Golgi apparatus
0.36	GO:0005765	lysosomal membrane
0.34	GO:0098793	presynapse
0.34	GO:0030136	clathrin-coated vesicle

sp|Q9Y2T3|GUAD_HUMAN
Guanine deaminase
Search

GDA

0.54	Guanine deaminase

0.83	GO:0006147	guanine catabolic process
0.35	GO:0031116	positive regulation of microtubule polymerization
0.35	GO:0006195	purine nucleotide catabolic process
0.34	GO:0007399	nervous system development

0.83	GO:0008892	guanine deaminase activity
0.63	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.83

EC:3.5.4.3

GO:0008892

sp|Q9Y2T4|2ABG_HUMAN
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
Search

PPP2R2C

0.66	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.50	GO:0070262	peptidyl-serine dephosphorylation
0.45	GO:0000278	mitotic cell cycle
0.43	GO:0032502	developmental process

0.80	GO:0019888	protein phosphatase regulator activity
0.46	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0005515	protein binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.43	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2T5|GPR52_HUMAN
Probable G-protein coupled receptor 52
Search

GPR52

0.94	G protein-coupled receptor 52

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0042493	response to drug
0.42	GO:0046627	negative regulation of insulin receptor signaling pathway
0.41	GO:0040018	positive regulation of multicellular organism growth
0.40	GO:0042593	glucose homeostasis
0.39	GO:0007610	behavior
0.36	GO:0043547	positive regulation of GTPase activity
0.36	GO:0007210	serotonin receptor signaling pathway
0.36	GO:0007618	mating
0.35	GO:0007049	cell cycle

0.72	GO:0004930	G-protein coupled receptor activity
0.44	GO:0030594	neurotransmitter receptor activity
0.36	GO:0005096	GTPase activator activity
0.36	GO:0099589	serotonin receptor activity
0.32	GO:0051378	serotonin binding
0.32	GO:0009881	photoreceptor activity

0.37	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

sp|Q9Y2T6|GPR55_HUMAN
G-protein coupled receptor 55
Search

GPR55

0.76	G-protein coupled receptor 55

0.74	GO:0007202	activation of phospholipase C activity
0.73	GO:0038171	cannabinoid signaling pathway
0.72	GO:0045671	negative regulation of osteoclast differentiation
0.72	GO:0045453	bone resorption
0.72	GO:0035025	positive regulation of Rho protein signal transduction
0.68	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.54	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.37	GO:0050881	musculoskeletal movement
0.36	GO:0007602	phototransduction
0.36	GO:0007601	visual perception

0.73	GO:0004949	cannabinoid receptor activity
0.37	GO:0009881	photoreceptor activity
0.35	GO:0070915	lysophosphatidic acid receptor activity
0.35	GO:0004974	leukotriene receptor activity
0.33	GO:0004950	chemokine receptor activity

0.57

GO:0005887

integral component of plasma membrane

sp|Q9Y2T7|YBOX2_HUMAN
Y-box-binding protein 2
Search

YBX2

0.95	TSH receptor suppressor element-binding protein-1

0.57	GO:0006355	regulation of transcription, DNA-templated
0.48	GO:0048255	mRNA stabilization
0.46	GO:1903608	protein localization to cytoplasmic stress granule
0.45	GO:0051154	negative regulation of striated muscle cell differentiation
0.44	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.43	GO:0010629	negative regulation of gene expression
0.43	GO:0006366	transcription by RNA polymerase II
0.43	GO:0048856	anatomical structure development
0.42	GO:0032501	multicellular organismal process
0.42	GO:1903508	positive regulation of nucleic acid-templated transcription

0.55	GO:0003677	DNA binding
0.44	GO:0003682	chromatin binding
0.44	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0003723	RNA binding
0.42	GO:0051020	GTPase binding
0.41	GO:0008190	eukaryotic initiation factor 4E binding
0.38	GO:0045182	translation regulator activity
0.37	GO:0043021	ribonucleoprotein complex binding
0.37	GO:0008289	lipid binding

0.55	GO:0001650	fibrillar center
0.48	GO:0071204	histone pre-mRNA 3'end processing complex
0.46	GO:0070937	CRD-mediated mRNA stability complex
0.45	GO:0005689	U12-type spliceosomal complex
0.44	GO:0010494	cytoplasmic stress granule
0.43	GO:0031965	nuclear membrane
0.40	GO:0005829	cytosol
0.39	GO:0005844	polysome
0.36	GO:0005576	extracellular region
0.34	GO:1990124	messenger ribonucleoprotein complex

0.34

GO:0003755

sp|Q9Y2U2|KCNK7_HUMAN
Potassium channel subfamily K member 7
Search

KCNK7

0.97	Potassium two pore domain channel subfamily K member 7

0.72	GO:0071805	potassium ion transmembrane transport
0.56	GO:0030322	stabilization of membrane potential
0.40	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0003015	heart process

0.76	GO:0005267	potassium channel activity
0.56	GO:0022840	leak channel activity
0.40	GO:0022832	voltage-gated channel activity
0.40	GO:0022839	ion gated channel activity
0.39	GO:0008381	mechanosensitive ion channel activity

0.46

GO:0005887

integral component of plasma membrane

sp|Q9Y2U5|M3K2_HUMAN
Mitogen-activated protein kinase kinase kinase 2
Search

MAP3K2

0.90	Mitogen-activated protein kinase kinase kinase 2

0.62	GO:0006468	protein phosphorylation
0.55	GO:0071260	cellular response to mechanical stimulus
0.51	GO:0051173	positive regulation of nitrogen compound metabolic process
0.51	GO:0010604	positive regulation of macromolecule metabolic process
0.51	GO:0031325	positive regulation of cellular metabolic process
0.49	GO:0009891	positive regulation of biosynthetic process
0.48	GO:0031098	stress-activated protein kinase signaling cascade
0.47	GO:0051347	positive regulation of transferase activity
0.46	GO:0045859	regulation of protein kinase activity
0.45	GO:0007346	regulation of mitotic cell cycle

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.40	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0046872	metal ion binding

0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

sp|Q9Y2U8|MAN1_HUMAN
Inner nuclear membrane protein Man1
Search

LEMD3

0.90	LEM domain containing 3

0.82	GO:0006997	nucleus organization
0.81	GO:0001525	angiogenesis
0.73	GO:1902531	regulation of intracellular signal transduction
0.61	GO:0032926	negative regulation of activin receptor signaling pathway
0.60	GO:0030514	negative regulation of BMP signaling pathway
0.58	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.50	GO:0070197	meiotic attachment of telomere to nuclear envelope
0.47	GO:0010256	endomembrane system organization
0.43	GO:0061024	membrane organization
0.39	GO:0043534	blood vessel endothelial cell migration

0.50	GO:0003676	nucleic acid binding
0.46	GO:0003682	chromatin binding
0.37	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.34	GO:0005515	protein binding

0.83	GO:0005637	nuclear inner membrane
0.83	GO:0044453	nuclear membrane part
0.76	GO:0031301	integral component of organelle membrane

0.37	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.37	KEGG:R07607	GO:0033743

sp|Q9Y2U9|KLDC2_HUMAN
Kelch domain-containing protein 2
Search

KLHDC2

0.97	Kelch domain-containing protein 2

0.36

GO:0005515

protein binding

0.76	GO:0031965	nuclear membrane
0.74	GO:0016604	nuclear body
0.46	GO:0005829	cytosol

sp|Q9Y2V0|CO041_HUMAN
Uncharacterized protein C15orf41
Search

0.30

GO:0044425

membrane part

sp|Q9Y2V2|CHSP1_HUMAN
Calcium-regulated heat-stable protein 1
Search

CARHSP1

0.97	Calcium regulated heat stable protein 1

0.54	GO:0043488	regulation of mRNA stability
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:0019722	calcium-mediated signaling

0.54	GO:0003730	mRNA 3'-UTR binding
0.50	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.54	GO:0043186	P granule
0.53	GO:0000177	cytoplasmic exosome (RNase complex)
0.46	GO:0005829	cytosol
0.36	GO:0000932	P-body
0.35	GO:0070062	extracellular exosome

sp|Q9Y2V3|RX_HUMAN
Retinal homeobox protein Rx
Search

RAX

0.91	Retina and anterior neural fold homeobox

0.73	GO:0043010	camera-type eye development
0.68	GO:0006366	transcription by RNA polymerase II
0.63	GO:0007601	visual perception
0.60	GO:0021854	hypothalamus development
0.57	GO:0060173	limb development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0007389	pattern specification process
0.53	GO:1902680	positive regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.38	GO:0019905	syntaxin binding
0.34	GO:0003746	translation elongation factor activity
0.33	GO:0005537	mannose binding

0.61	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9Y2V7|COG6_HUMAN
Conserved oligomeric Golgi complex subunit 6
Search

COG6

0.90	Component of oligomeric golgi complex 6

0.82	GO:0006891	intra-Golgi vesicle-mediated transport
0.49	GO:0070085	glycosylation
0.36	GO:0015031	protein transport
0.34	GO:0006888	ER to Golgi vesicle-mediated transport

0.33

GO:0005515

protein binding

0.81	GO:0017119	Golgi transport complex
0.38	GO:0000139	Golgi membrane
0.35	GO:0005802	trans-Golgi network

sp|Q9Y2W1|TR150_HUMAN
Thyroid hormone receptor-associated protein 3
Search

THRAP3

0.97	Thyroid hormone receptor associated protein 3

0.72	GO:0008380	RNA splicing
0.62	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.62	GO:0030521	androgen receptor signaling pathway
0.61	GO:0048255	mRNA stabilization
0.61	GO:0042753	positive regulation of circadian rhythm
0.60	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.58	GO:0007623	circadian rhythm
0.57	GO:0006367	transcription initiation from RNA polymerase II promoter
0.56	GO:0000956	nuclear-transcribed mRNA catabolic process
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II

0.63	GO:0046966	thyroid hormone receptor binding
0.60	GO:0051219	phosphoprotein binding
0.59	GO:0001046	core promoter sequence-specific DNA binding
0.57	GO:0003713	transcription coactivator activity
0.57	GO:0001104	RNA polymerase II transcription cofactor activity
0.49	GO:0004872	receptor activity
0.37	GO:0042809	vitamin D receptor binding
0.35	GO:0005524	ATP binding
0.35	GO:0003723	RNA binding

0.61	GO:0035145	exon-exon junction complex
0.58	GO:0016607	nuclear speck
0.56	GO:0016592	mediator complex
0.38	GO:0070062	extracellular exosome
0.32	GO:0015630	microtubule cytoskeleton

sp|Q9Y2W2|WBP11_HUMAN
WW domain-binding protein 11
Search

WBP11

0.90	WW domain-binding protein 11

0.62	GO:0006396	RNA processing
0.60	GO:1903146	regulation of autophagy of mitochondrion
0.60	GO:1903955	positive regulation of protein targeting to mitochondrion
0.48	GO:0043666	regulation of phosphoprotein phosphatase activity
0.44	GO:0016071	mRNA metabolic process
0.38	GO:0016072	rRNA metabolic process
0.38	GO:0042254	ribosome biogenesis

0.61	GO:0050699	WW domain binding
0.49	GO:0019888	protein phosphatase regulator activity
0.35	GO:0003697	single-stranded DNA binding
0.35	GO:0003723	RNA binding
0.32	GO:0005199	structural constituent of cell wall

0.53	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.46	GO:0005681	spliceosomal complex
0.37	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2W3|S45A1_HUMAN
Proton-associated sugar transporter A
Search

SLC45A1

0.97	Proton-associated sugar transporter A

0.57	GO:0008643	carbohydrate transport
0.53	GO:0055085	transmembrane transport
0.32	GO:0005985	sucrose metabolic process

0.42	GO:0008515	sucrose transmembrane transporter activity
0.38	GO:0015293	symporter activity
0.35	GO:0005355	glucose transmembrane transporter activity
0.31	GO:0015078	hydrogen ion transmembrane transporter activity

0.38	GO:0005887	integral component of plasma membrane
0.33	GO:0009705	plant-type vacuole membrane
0.32	GO:0005801	cis-Golgi network

sp|Q9Y2W6|TDRKH_HUMAN
Tudor and KH domain-containing protein
Search

TDRKH

0.91	Tudor and KH domain containing

0.60	GO:0043046	DNA methylation involved in gamete generation
0.60	GO:0034587	piRNA metabolic process
0.58	GO:0007140	male meiotic nuclear division
0.57	GO:0009566	fertilization
0.55	GO:0007283	spermatogenesis
0.38	GO:0031047	gene silencing by RNA
0.37	GO:0030154	cell differentiation
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0016310	phosphorylation

0.59	GO:0003723	RNA binding
0.34	GO:0016301	kinase activity
0.34	GO:0005515	protein binding
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0004386	helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding
0.31	GO:0008094	DNA-dependent ATPase activity

0.62	GO:0071547	piP-body
0.61	GO:0071546	pi-body
0.46	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9Y2W7|CSEN_HUMAN
Calsenilin
Search

KCNIP3

0.94	Potassium voltage-gated channel interacting protein 3

0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0031018	endocrine pancreas development
0.43	GO:1901379	regulation of potassium ion transmembrane transport
0.39	GO:0065009	regulation of molecular function
0.39	GO:0072659	protein localization to plasma membrane
0.38	GO:0006915	apoptotic process
0.37	GO:0071805	potassium ion transmembrane transport
0.37	GO:0048266	behavioral response to pain
0.37	GO:0019233	sensory perception of pain
0.36	GO:0043523	regulation of neuron apoptotic process

0.70	GO:0005509	calcium ion binding
0.53	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0015459	potassium channel regulator activity
0.38	GO:0044325	ion channel binding
0.38	GO:0005267	potassium channel activity
0.38	GO:0022832	voltage-gated channel activity
0.37	GO:0022839	ion gated channel activity
0.37	GO:0008381	mechanosensitive ion channel activity
0.37	GO:0048306	calcium-dependent protein binding

0.41	GO:0008076	voltage-gated potassium channel complex
0.38	GO:0043679	axon terminus
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon
0.37	GO:0032993	protein-DNA complex
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus

sp|Q9Y2X0|MED16_HUMAN
Mediator of RNA polymerase II transcription subunit 16
Search

MED16

0.95	Mediator of RNA polymerase II transcription subunit 16

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030521	androgen receptor signaling pathway
0.50	GO:1902680	positive regulation of RNA biosynthetic process

0.57	GO:0030375	thyroid hormone receptor coactivator activity
0.56	GO:0046966	thyroid hormone receptor binding
0.45	GO:0004872	receptor activity
0.36	GO:0042809	vitamin D receptor binding
0.32	GO:0003676	nucleic acid binding
0.30	GO:0003824	catalytic activity

0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q9Y2X3|NOP58_HUMAN
Nucleolar protein 58
Search

NOP58

0.79	Nucleolar protein 58

0.80	GO:0048254	snoRNA localization
0.54	GO:0000154	rRNA modification
0.38	GO:0016049	cell growth

0.79	GO:0001094	TFIID-class transcription factor binding
0.75	GO:0051117	ATPase binding
0.75	GO:0030515	snoRNA binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0070761	pre-snoRNP complex
0.75	GO:0015030	Cajal body
0.73	GO:0001650	fibrillar center
0.72	GO:0005732	small nucleolar ribonucleoprotein complex
0.61	GO:0005829	cytosol
0.59	GO:0032040	small-subunit processome
0.51	GO:0019013	viral nucleocapsid
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2X7|GIT1_HUMAN
ARF GTPase-activating protein GIT1
Search

GIT1

0.92	G protein-coupled receptor kinase interacting ArfGAP 1

0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0048013	ephrin receptor signaling pathway
0.57	GO:0032465	regulation of cytokinesis
0.50	GO:0001525	angiogenesis
0.41	GO:0016310	phosphorylation
0.37	GO:0048266	behavioral response to pain
0.34	GO:0034613	cellular protein localization

0.75	GO:0005096	GTPase activator activity
0.55	GO:0032403	protein complex binding
0.52	GO:0046872	metal ion binding
0.42	GO:0016301	kinase activity

0.59	GO:0005925	focal adhesion
0.51	GO:0005829	cytosol
0.40	GO:0005654	nucleoplasm
0.36	GO:0032587	ruffle membrane

sp|Q9Y2X8|UB2D4_HUMAN
Ubiquitin-conjugating enzyme E2 D4
Search

0.83	Ubiquitin-conjugating enzyme E2-17 kDa

0.59	GO:0070936	protein K48-linked ubiquitination
0.54	GO:1902916	positive regulation of protein polyubiquitination
0.50	GO:0035519	protein K29-linked ubiquitination
0.50	GO:0044314	protein K27-linked ubiquitination
0.49	GO:0085020	protein K6-linked ubiquitination
0.48	GO:0070979	protein K11-linked ubiquitination
0.48	GO:0070534	protein K63-linked ubiquitination
0.47	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0039020	pronephric nephron tubule development
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.59	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.34	GO:0004222	metalloendopeptidase activity
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0016874	ligase activity

0.48	GO:0000151	ubiquitin ligase complex
0.42	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.34

GO:0004222

sp|Q9Y2X9|ZN281_HUMAN
Zinc finger protein 281
Search

ZNF281

0.95	Zinc finger domain-containing protein (Fragment)

0.59	GO:0010172	embryonic body morphogenesis
0.57	GO:0048863	stem cell differentiation
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0030097	hemopoiesis

0.57	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0001047	core promoter binding
0.56	GO:0003714	transcription corepressor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.50	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2Y0|AR2BP_HUMAN
ADP-ribosylation factor-like protein 2-binding protein
Search

ARL2BP

0.92	ADP-ribosylation factor-like protein 2-binding protein (Fragment)

0.82	GO:0051457	maintenance of protein location in nucleus
0.81	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.54	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:0050796	regulation of insulin secretion
0.46	GO:0050790	regulation of catalytic activity
0.39	GO:0007165	signal transduction
0.37	GO:0051253	negative regulation of RNA metabolic process
0.37	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.37	GO:0010629	negative regulation of gene expression
0.37	GO:0018193	peptidyl-amino acid modification

0.74	GO:0003713	transcription coactivator activity
0.49	GO:0030695	GTPase regulator activity
0.44	GO:0005515	protein binding
0.43	GO:0008047	enzyme activator activity

0.79	GO:0005758	mitochondrial intermembrane space
0.75	GO:0030496	midbody
0.75	GO:0005815	microtubule organizing center
0.70	GO:0005929	cilium
0.68	GO:0005819	spindle
0.61	GO:0005634	nucleus
0.44	GO:0005759	mitochondrial matrix
0.42	GO:0005829	cytosol

sp|Q9Y2Y1|RPC10_HUMAN
DNA-directed RNA polymerase III subunit RPC10
Search

POLR3K

0.51	DNA-directed RNA polymerase subunit

0.81	GO:0006379	mRNA cleavage
0.58	GO:0006351	transcription, DNA-templated
0.47	GO:0061484	hematopoietic stem cell homeostasis
0.37	GO:0045087	innate immune response
0.37	GO:0051607	defense response to virus
0.36	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0080090	regulation of primary metabolic process
0.36	GO:0031323	regulation of cellular metabolic process
0.36	GO:0051171	regulation of nitrogen compound metabolic process
0.35	GO:0009889	regulation of biosynthetic process

0.69	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.35	GO:0017171	serine hydrolase activity
0.34	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.34	GO:0004896	cytokine receptor activity

0.68	GO:0005730	nucleolus
0.47	GO:0005666	DNA-directed RNA polymerase III complex
0.34	GO:0042720	mitochondrial inner membrane peptidase complex
0.33	GO:0005829	cytosol
0.33	GO:0000139	Golgi membrane
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0003899

sp|Q9Y2Y4|ZBT32_HUMAN
Zinc finger and BTB domain-containing protein 32
Search

ZBTB32

0.97	Zinc finger and BTB domain-containing protein 32

0.47	GO:0032332	positive regulation of chondrocyte differentiation
0.46	GO:0048133	male germ-line stem cell asymmetric division
0.46	GO:0051138	positive regulation of NK T cell differentiation
0.46	GO:0045600	positive regulation of fat cell differentiation
0.46	GO:0030097	hemopoiesis
0.46	GO:0045778	positive regulation of ossification
0.46	GO:0035116	embryonic hindlimb morphogenesis
0.45	GO:0035136	forelimb morphogenesis
0.45	GO:0051216	cartilage development
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.47	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.43	GO:0042803	protein homodimerization activity
0.40	GO:0008270	zinc ion binding
0.40	GO:0003714	transcription corepressor activity
0.38	GO:0018024	histone-lysine N-methyltransferase activity
0.36	GO:0008022	protein C-terminus binding
0.35	GO:0019904	protein domain specific binding
0.33	GO:0004842	ubiquitin-protein transferase activity

0.45	GO:0016605	PML body
0.44	GO:0017053	transcriptional repressor complex
0.44	GO:0016607	nuclear speck
0.38	GO:0043234	protein complex
0.37	GO:0035097	histone methyltransferase complex
0.36	GO:0000228	nuclear chromosome
0.34	GO:0005829	cytosol
0.33	GO:0031463	Cul3-RING ubiquitin ligase complex
0.33	GO:0005886	plasma membrane
0.33	GO:0005739	mitochondrion

0.38	EC:2.1.1.43	GO:0018024
0.33	KEGG:R03876	GO:0004842

sp|Q9Y2Y6|TMM98_HUMAN
Transmembrane protein 98
Search

TMEM98

0.97	Transmembrane protein 98

0.53	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|Q9Y2Y8|PRG3_HUMAN
Proteoglycan 3
Search

0.97	Bone marrow proteoglycan

0.74	GO:0006955	immune response
0.73	GO:0045575	basophil activation
0.72	GO:0001694	histamine biosynthetic process
0.72	GO:0001819	positive regulation of cytokine production
0.70	GO:0045414	regulation of interleukin-8 biosynthetic process
0.69	GO:0019370	leukotriene biosynthetic process
0.68	GO:0042119	neutrophil activation
0.68	GO:0042554	superoxide anion generation
0.61	GO:0002215	defense response to nematode
0.60	GO:0017148	negative regulation of translation

0.44	GO:0030246	carbohydrate binding
0.39	GO:0008201	heparin binding

0.42	GO:1904724	tertiary granule lumen
0.42	GO:0035580	specific granule lumen
0.39	GO:0005576	extracellular region
0.38	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0030133	transport vesicle

sp|Q9Y2Y9|KLF13_HUMAN
Krueppel-like factor 13
Search

KLF13

0.94	Kruppel like factor 13

0.51	GO:0045647	negative regulation of erythrocyte differentiation
0.47	GO:0008285	negative regulation of cell proliferation
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.46	GO:0006366	transcription by RNA polymerase II
0.45	GO:0045893	positive regulation of transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9Y2Z0|SGT1_HUMAN
Protein SGT1 homolog
Search

SUGT1

0.90	MIS12 kinetochore complex assembly cochaperone

0.87	GO:0043947	positive regulation by host of symbiont catalytic activity
0.76	GO:0031647	regulation of protein stability
0.42	GO:0000278	mitotic cell cycle
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.39	GO:0005515	protein binding
0.37	GO:0043565	sequence-specific DNA binding
0.37	GO:0003700	DNA binding transcription factor activity

0.58	GO:0043234	protein complex
0.45	GO:0005634	nucleus
0.43	GO:0000775	chromosome, centromeric region
0.43	GO:0000151	ubiquitin ligase complex
0.41	GO:0005829	cytosol

sp|Q9Y2Z2|MTO1_HUMAN
Protein MTO1 homolog, mitochondrial
Search

MTO1

0.80	Mitochondrial tRNA translation optimization 1

0.76	GO:0002098	tRNA wobble uridine modification
0.49	GO:0070900	mitochondrial tRNA modification
0.44	GO:0030488	tRNA methylation

0.66	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0003723	RNA binding

0.40	GO:0005739	mitochondrion
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y2Z4|SYYM_HUMAN
Tyrosine--tRNA ligase, mitochondrial
Search

YARS2

0.52	Tyrosine--tRNA ligase

0.77	GO:0006437	tyrosyl-tRNA aminoacylation
0.57	GO:0070127	tRNA aminoacylation for mitochondrial protein translation
0.34	GO:0006508	proteolysis

0.77	GO:0004831	tyrosine-tRNA ligase activity
0.60	GO:0072545	tyrosine binding
0.57	GO:0003723	RNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042803	protein homodimerization activity
0.36	GO:0004197	cysteine-type endopeptidase activity

0.54	GO:0016604	nuclear body
0.48	GO:0005737	cytoplasm

0.77	EC:6.1.1.1	GO:0004831
0.77	KEGG:R02918	GO:0004831

sp|Q9Y2Z9|COQ6_HUMAN
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
Search

COQ6

0.75	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

0.73	GO:0006744	ubiquinone biosynthetic process
0.52	GO:0055114	oxidation-reduction process

0.73	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.71	GO:0071949	FAD binding
0.69	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.32	GO:0003676	nucleic acid binding

0.70	GO:0031314	extrinsic component of mitochondrial inner membrane
0.62	GO:0005794	Golgi apparatus
0.59	GO:0042995	cell projection
0.30	GO:0016021	integral component of membrane

0.73

EC:1.14.13

GO:0016709

sp|Q9Y303|NAGA_HUMAN
N-acetylglucosamine-6-phosphate deacetylase
Search

AMDHD2

0.55	LOW QUALITY PROTEIN: N-acetylglucosamine-6-phosphate deacetylase

0.75	GO:0006044	N-acetylglucosamine metabolic process
0.55	GO:0005975	carbohydrate metabolic process
0.46	GO:1901072	glucosamine-containing compound catabolic process
0.40	GO:0019262	N-acetylneuraminate catabolic process
0.37	GO:0015991	ATP hydrolysis coupled proton transport
0.35	GO:0006048	UDP-N-acetylglucosamine biosynthetic process

0.77	GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity
0.51	GO:0046872	metal ion binding
0.35	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.37	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.77

EC:3.5.1.25

GO:0008448

sp|Q9Y305|ACOT9_HUMAN
Acyl-coenzyme A thioesterase 9, mitochondrial
Search

ACOT9

0.92	Acyl-coenzyme A thioesterase 9, mitochondrial

0.40

GO:0006637

acyl-CoA metabolic process

0.51	GO:0016787	hydrolase activity
0.34	GO:0005515	protein binding

0.38	GO:0005739	mitochondrion
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.51

GO:0016787

sp|Q9Y312|AAR2_HUMAN
Protein AAR2 homolog
Search

AAR2

0.97	AAR2 splicing factor homolog (S. cerevisiae)

0.73	GO:0000244	spliceosomal tri-snRNP complex assembly
0.47	GO:0030866	cortical actin cytoskeleton organization

0.48	GO:0003779	actin binding
0.43	GO:0005198	structural molecule activity

0.52	GO:0005681	spliceosomal complex
0.46	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y314|NOSIP_HUMAN
Nitric oxide synthase-interacting protein
Search

NOSIP

0.93	Nitric oxide synthase interacting protein (Fragment)

0.70	GO:0016567	protein ubiquitination
0.58	GO:0051001	negative regulation of nitric-oxide synthase activity
0.39	GO:0007275	multicellular organism development

0.74	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.34	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y315|DEOC_HUMAN
Deoxyribose-phosphate aldolase
Search

DERA

0.53	Deoxyribose-phosphate aldolase

0.78	GO:0009264	deoxyribonucleotide catabolic process
0.58	GO:0046121	deoxyribonucleoside catabolic process
0.43	GO:0016052	carbohydrate catabolic process
0.41	GO:0046386	deoxyribose phosphate catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006098	pentose-phosphate shunt

0.80

GO:0004139

deoxyribose-phosphate aldolase activity

0.49	GO:0005737	cytoplasm
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

0.80	EC:4.1.2.4	GO:0004139
0.80	KEGG:R01066	GO:0004139

sp|Q9Y316|MEMO1_HUMAN
Protein MEMO1
Search

MEMO1

0.58	Mediator of cell motility 1

0.79	GO:0032886	regulation of microtubule-based process
0.39	GO:2000145	regulation of cell motility
0.35	GO:0055114	oxidation-reduction process

0.39	GO:0051213	dioxygenase activity
0.39	GO:0042277	peptide binding
0.36	GO:0005515	protein binding

0.51	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y320|TMX2_HUMAN
Thioredoxin-related transmembrane protein 2
Search

TMX2

0.96	Thioredoxin-related transmembrane protein 2-B

0.66

GO:0045454

cell redox homeostasis

0.30	GO:0044425	membrane part
0.30	GO:0005623	cell

sp|Q9Y324|FCF1_HUMAN
rRNA-processing protein FCF1 homolog
Search

FCF1

0.83	FCF1 small subunit (SSU) processome component homolog

0.53	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.50	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.34

GO:0003723

RNA binding

0.79	GO:0032040	small-subunit processome
0.45	GO:0005730	nucleolus
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9Y328|NSG2_HUMAN
Neuron-specific protein family member 2
Search

HGNC:24955

0.97	Neuronal vesicle trafficking-associated protein 2

0.85	GO:0007212	dopamine receptor signaling pathway
0.83	GO:0048268	clathrin coat assembly
0.51	GO:0016197	endosomal transport
0.47	GO:0099627	neurotransmitter receptor cycle
0.46	GO:1903540	establishment of protein localization to postsynaptic membrane
0.46	GO:0098877	neurotransmitter receptor transport to plasma membrane
0.46	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.45	GO:0042982	amyloid precursor protein metabolic process
0.45	GO:0001881	receptor recycling
0.45	GO:0097120	receptor localization to synapse

0.85	GO:0032051	clathrin light chain binding
0.35	GO:0003730	mRNA 3'-UTR binding
0.35	GO:0045182	translation regulator activity
0.34	GO:0005102	receptor binding
0.32	GO:0003677	DNA binding

0.52	GO:0005768	endosome
0.50	GO:1990674	Golgi cis cisterna membrane
0.45	GO:0030659	cytoplasmic vesicle membrane
0.44	GO:0016328	lateral plasma membrane
0.43	GO:0098805	whole membrane
0.43	GO:0043202	lysosomal lumen
0.43	GO:0098794	postsynapse
0.43	GO:0097060	synaptic membrane
0.42	GO:0032588	trans-Golgi network membrane
0.42	GO:0030425	dendrite

sp|Q9Y330|ZBT12_HUMAN
Zinc finger and BTB domain-containing protein 12
Search

ZBTB12

0.97	LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 12

0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0034968	histone lysine methylation

0.51	GO:0003676	nucleic acid binding
0.39	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding
0.34	GO:0002039	p53 binding
0.34	GO:0018024	histone-lysine N-methyltransferase activity

0.41	GO:0005634	nucleus
0.39	GO:0005739	mitochondrion
0.33	GO:0005694	chromosome

0.34

GO:0018024

sp|Q9Y333|LSM2_HUMAN
U6 snRNA-associated Sm-like protein LSm2
Search

LSM2

0.80	U6 snRNA-associated Sm-like protein LSm2

0.70	GO:0000398	mRNA splicing, via spliceosome
0.37	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.37	GO:0006438	valyl-tRNA aminoacylation
0.36	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.36	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0006402	mRNA catabolic process
0.34	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.34	GO:0022618	ribonucleoprotein complex assembly

0.56	GO:0003723	RNA binding
0.52	GO:0017160	Ral GTPase binding
0.38	GO:0000213	tRNA-intron endonuclease activity
0.37	GO:0004832	valine-tRNA ligase activity
0.37	GO:0019901	protein kinase binding
0.36	GO:0002161	aminoacyl-tRNA editing activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005688	U6 snRNP
0.76	GO:0000932	P-body
0.75	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.71	GO:0005681	spliceosomal complex
0.48	GO:1990726	Lsm1-7-Pat1 complex
0.44	GO:1902494	catalytic complex
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.33	GO:0031966	mitochondrial membrane

0.38	EC:3.1.27.9	GO:0000213
0.37	KEGG:R03665	GO:0004832

sp|Q9Y334|VWA7_HUMAN
von Willebrand factor A domain-containing protein 7
Search

VWA7

0.94	von Willebrand factor A domain-containing protein 7

0.53	GO:0006438	valyl-tRNA aminoacylation
0.51	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.49	GO:0006397	mRNA processing

0.53	GO:0004832	valine-tRNA ligase activity
0.51	GO:0002161	aminoacyl-tRNA editing activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0005576	extracellular region
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0005737	cytoplasm
0.34	GO:0030288	outer membrane-bounded periplasmic space
0.30	GO:0016020	membrane

0.53	EC:6.1.1.9	GO:0004832
0.53	KEGG:R03665	GO:0004832

sp|Q9Y336|SIGL9_HUMAN
Sialic acid-binding Ig-like lectin 9
Search

0.95	Sialic acid binding Ig like lectin 9

0.42	GO:0007155	cell adhesion
0.39	GO:0043312	neutrophil degranulation
0.38	GO:0048583	regulation of response to stimulus
0.38	GO:0002682	regulation of immune system process
0.37	GO:0023052	signaling
0.37	GO:0007154	cell communication
0.36	GO:0060101	negative regulation of phagocytosis, engulfment
0.36	GO:0051716	cellular response to stimulus
0.34	GO:0008285	negative regulation of cell proliferation

0.49	GO:0030246	carbohydrate binding
0.37	GO:0004872	receptor activity
0.36	GO:0033691	sialic acid binding
0.35	GO:0005515	protein binding
0.35	GO:0004871	signal transducer activity

0.43	GO:0009897	external side of plasma membrane
0.38	GO:0030667	secretory granule membrane
0.38	GO:0005634	nucleus
0.38	GO:0005887	integral component of plasma membrane
0.35	GO:0070820	tertiary granule
0.35	GO:0042581	specific granule
0.34	GO:0005576	extracellular region

sp|Q9Y337|KLK5_HUMAN
Kallikrein-5
Search

0.93	Cationic trypsinogen

0.61	GO:0006508	proteolysis
0.55	GO:0002803	positive regulation of antibacterial peptide production
0.55	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.46	GO:0022617	extracellular matrix disassembly
0.46	GO:0097186	amelogenesis
0.43	GO:0007586	digestion
0.40	GO:0030163	protein catabolic process
0.38	GO:0008544	epidermis development
0.38	GO:0070684	seminal clot liquefaction
0.37	GO:0060429	epithelium development

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding

0.56	GO:0097209	epidermal lamellar body
0.53	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.34	GO:0005829	cytosol

0.69

GO:0004252

sp|Q9Y342|PLLP_HUMAN
Plasmolipin
Search

PLLP

0.97	Plasmolipin

0.53	GO:0001766	membrane raft polarization
0.51	GO:0042552	myelination
0.43	GO:0008104	protein localization
0.40	GO:0048546	digestive tract morphogenesis
0.39	GO:0009611	response to wounding
0.39	GO:0030100	regulation of endocytosis
0.36	GO:0006811	ion transport
0.35	GO:0010469	regulation of receptor activity
0.34	GO:0006935	chemotaxis
0.33	GO:0043043	peptide biosynthetic process

0.52	GO:0019911	structural constituent of myelin sheath
0.35	GO:0005125	cytokine activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity

0.49	GO:0045121	membrane raft
0.42	GO:0005654	nucleoplasm
0.41	GO:0043218	compact myelin
0.37	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.33	GO:0005840	ribosome
0.33	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.30	GO:0016021	integral component of membrane

0.33	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.33	KEGG:R00842	GO:0004367

sp|Q9Y343|SNX24_HUMAN
Sorting nexin-24
Search

SNX24

0.97	Sorting nexin-24 isoform B

0.37	GO:0015031	protein transport
0.34	GO:0042147	retrograde transport, endosome to Golgi
0.33	GO:0070727	cellular macromolecule localization

0.76

GO:0035091

phosphatidylinositol binding

0.39	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0030904	retromer complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y345|SC6A5_HUMAN
Sodium- and chloride-dependent glycine transporter 2
Search

SLC6A5

0.47	Sodium- and chloride-dependent glycine transporter 2

0.75	GO:0006836	neurotransmitter transport
0.63	GO:0060012	synaptic transmission, glycinergic
0.60	GO:0043092	L-amino acid import
0.55	GO:0015804	neutral amino acid transport
0.54	GO:0055085	transmembrane transport
0.52	GO:0015893	drug transport
0.46	GO:0006812	cation transport
0.36	GO:0009636	response to toxic substance
0.34	GO:0006520	cellular amino acid metabolic process

0.77	GO:0005328	neurotransmitter:sodium symporter activity
0.61	GO:0015187	glycine transmembrane transporter activity
0.56	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity
0.56	GO:0005283	sodium:amino acid symporter activity
0.55	GO:0015296	anion:cation symporter activity
0.35	GO:0046872	metal ion binding

0.44

GO:0005887

integral component of plasma membrane

sp|Q9Y365|PCTL_HUMAN
PCTP-like protein
Search

STARD10

0.97	START domain-containing protein 10

0.62	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.61	GO:0032782	bile acid secretion
0.36	GO:0006869	lipid transport
0.35	GO:0006656	phosphatidylcholine biosynthetic process

0.72	GO:0008289	lipid binding
0.33	GO:0005515	protein binding

0.63	GO:0046581	intercellular canaliculus
0.60	GO:0005902	microvillus
0.51	GO:0005829	cytosol
0.35	GO:0031514	motile cilium
0.30	GO:0016020	membrane

sp|Q9Y366|IFT52_HUMAN
Intraflagellar transport protein 52 homolog
Search

IFT52

0.94	Intraflagellar transport protein 52

0.60	GO:0035720	intraciliary anterograde transport
0.56	GO:0042733	embryonic digit morphogenesis
0.56	GO:0001947	heart looping
0.56	GO:0070613	regulation of protein processing
0.56	GO:1905515	non-motile cilium assembly
0.56	GO:0001841	neural tube formation
0.55	GO:0050680	negative regulation of epithelial cell proliferation
0.55	GO:0007224	smoothened signaling pathway
0.55	GO:0009953	dorsal/ventral pattern formation
0.36	GO:0035735	intraciliary transport involved in cilium assembly

0.35	GO:0008022	protein C-terminus binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016491	oxidoreductase activity

0.73	GO:0005929	cilium
0.58	GO:0044292	dendrite terminus
0.56	GO:0030992	intraciliary transport particle B
0.55	GO:0005815	microtubule organizing center
0.44	GO:0032838	plasma membrane bounded cell projection cytoplasm

0.34

GO:0004674

sp|Q9Y371|SHLB1_HUMAN
Endophilin-B1
Search

SH3GLB1

0.88	SH3 domain containing GRB2 like, endophilin B1

0.53	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.53	GO:1903778	protein localization to vacuolar membrane
0.52	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.52	GO:0048102	autophagic cell death
0.52	GO:2000786	positive regulation of autophagosome assembly
0.51	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.51	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.49	GO:0051084	'de novo' posttranslational protein folding
0.49	GO:0006654	phosphatidic acid biosynthetic process
0.47	GO:1905477	positive regulation of protein localization to membrane

0.51	GO:0005504	fatty acid binding
0.49	GO:0042171	lysophosphatidic acid acyltransferase activity
0.38	GO:0045296	cadherin binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0061778	intracellular chloride channel activity
0.34	GO:0022839	ion gated channel activity
0.33	GO:0008381	mechanosensitive ion channel activity
0.32	GO:0008270	zinc ion binding

0.49	GO:0005737	cytoplasm
0.41	GO:0043234	protein complex
0.40	GO:0030496	midbody
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043229	intracellular organelle
0.39	GO:0098805	whole membrane
0.38	GO:0012505	endomembrane system
0.38	GO:0019867	outer membrane
0.36	GO:0043230	extracellular organelle
0.36	GO:0031975	envelope

sp|Q9Y375|CIA30_HUMAN
Complex I intermediate-associated protein 30, mitochondrial
Search

NDUFAF1

0.89	NADH:ubiquinone oxidoreductase complex assembly factor 1

0.49	GO:0032981	mitochondrial respiratory chain complex I assembly
0.48	GO:0055093	response to hyperoxia
0.46	GO:0001666	response to hypoxia
0.46	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.45	GO:0042594	response to starvation
0.44	GO:0009408	response to heat
0.34	GO:0008654	phospholipid biosynthetic process

0.38	GO:0051082	unfolded protein binding
0.34	GO:0016780	phosphotransferase activity, for other substituted phosphate groups

0.64	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.40	GO:0045271	respiratory chain complex I
0.38	GO:1990204	oxidoreductase complex
0.36	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:2.7.8

GO:0016780

sp|Q9Y376|CAB39_HUMAN
Calcium-binding protein 39
Search

CAB39

0.94	Calcium-binding protein 39

0.85	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.80	GO:0032147	activation of protein kinase activity
0.79	GO:0018105	peptidyl-serine phosphorylation
0.77	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.64	GO:0023014	signal transduction by protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.48	GO:0051291	protein heterooligomerization

0.82	GO:0043539	protein serine/threonine kinase activator activity
0.75	GO:0019900	kinase binding
0.69	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0005509	calcium ion binding

0.44	GO:0005622	intracellular
0.41	GO:0070062	extracellular exosome
0.40	GO:0043234	protein complex

0.69

GO:0004674

sp|Q9Y383|LC7L2_HUMAN
Putative RNA-binding protein Luc7-like 2
Search

LUC7L2

0.82	Putative spliceosome subunit

0.84	GO:0006376	mRNA splice site selection
0.35	GO:0045843	negative regulation of striated muscle tissue development

0.76	GO:0003729	mRNA binding
0.38	GO:0019899	enzyme binding

0.82	GO:0005685	U1 snRNP
0.47	GO:0071004	U2-type prespliceosome
0.36	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

sp|Q9Y385|UB2J1_HUMAN
Ubiquitin-conjugating enzyme E2 J1
Search

UBE2J1

0.91	Ubiquitin-conjugating enzyme E2 J1 isoform A

0.59	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.59	GO:0042534	regulation of tumor necrosis factor biosynthetic process
0.56	GO:0018279	protein N-linked glycosylation via asparagine
0.55	GO:0007286	spermatid development
0.55	GO:0030433	ubiquitin-dependent ERAD pathway
0.52	GO:0016567	protein ubiquitination

0.57	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y388|RBMX2_HUMAN
RNA-binding motif protein, X-linked 2
Search

RBMX2

0.92	RNA-binding motif protein, X-linked

0.47	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.45	GO:0051028	mRNA transport
0.45	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0006405	RNA export from nucleus

0.58	GO:0003723	RNA binding
0.50	GO:0000384	first spliceosomal transesterification activity
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0070274	RES complex
0.48	GO:0071011	precatalytic spliceosome
0.48	GO:0005686	U2 snRNP
0.47	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0016020	membrane

sp|Q9Y394|DHRS7_HUMAN
Dehydrogenase/reductase SDR family member 7
Search

DHRS7

0.93	LOW QUALITY PROTEIN: dehydrogenase/reductase SDR family member 7

0.52	GO:0055114	oxidation-reduction process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process
0.31	GO:1903506	regulation of nucleic acid-templated transcription
0.31	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.31	GO:0010468	regulation of gene expression
0.31	GO:0016070	RNA metabolic process
0.31	GO:0034654	nucleobase-containing compound biosynthetic process

0.53	GO:0016491	oxidoreductase activity
0.33	GO:0003735	structural constituent of ribosome
0.31	GO:0003677	DNA binding

0.33	GO:0005840	ribosome
0.31	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.53

GO:0016491

sp|Q9Y397|ZDHC9_HUMAN
Palmitoyltransferase ZDHHC9
Search

ZDHHC9

0.55	Palmitoyltransferase

0.62	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.60	GO:0018345	protein palmitoylation
0.35	GO:0034613	cellular protein localization
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.60	GO:0002178	palmitoyltransferase complex
0.57	GO:0031228	intrinsic component of Golgi membrane
0.51	GO:0005783	endoplasmic reticulum
0.49	GO:0005829	cytosol
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0016021	integral component of membrane

0.80

EC:2.3.1.225

GO:0019706

sp|Q9Y399|RT02_HUMAN
28S ribosomal protein S2, mitochondrial
Search

MRPS2

0.95	Mitochondrial ribosomal protein S2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0003723	RNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0015935	small ribosomal subunit
0.53	GO:0005761	mitochondrial ribosome
0.41	GO:0031080	nuclear pore outer ring
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane

sp|Q9Y3A0|COQ4_HUMAN
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial
Search

COQ4

0.81	Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

0.72

GO:0006744

ubiquinone biosynthetic process

0.33

GO:0005515

protein binding

0.74	GO:0031314	extrinsic component of mitochondrial inner membrane
0.43	GO:0043234	protein complex

sp|Q9Y3A2|UTP11_HUMAN
Probable U3 small nucleolar RNA-associated protein 11
Search

UTP11

0.75	U3 small nucleolar RNA-associated protein 11

0.69	GO:0006364	rRNA processing
0.55	GO:0043065	positive regulation of apoptotic process
0.52	GO:0007399	nervous system development
0.47	GO:0042274	ribosomal small subunit biogenesis
0.38	GO:0034471	ncRNA 5'-end processing
0.36	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0009059	macromolecule biosynthetic process

0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.79	GO:0032040	small-subunit processome
0.69	GO:0005730	nucleolus
0.52	GO:0005615	extracellular space
0.44	GO:0019013	viral nucleocapsid
0.40	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3A3|PHOCN_HUMAN
MOB-like protein phocein
Search

MOB4

0.96	LOW QUALITY PROTEIN: MOB-like protein phocein

0.47	GO:0006457	protein folding
0.42	GO:0016310	phosphorylation
0.42	GO:0006900	vesicle budding from membrane

0.51	GO:0019900	kinase binding
0.43	GO:0016301	kinase activity
0.42	GO:0046872	metal ion binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005794	Golgi apparatus
0.52	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0043197	dendritic spine
0.50	GO:0098588	bounding membrane of organelle
0.50	GO:0043025	neuronal cell body
0.49	GO:0031984	organelle subcompartment
0.45	GO:0005829	cytosol

sp|Q9Y3A4|RRP7A_HUMAN
Ribosomal RNA-processing protein 7 homolog A
Search

RRP7A

0.96	Ribosomal RNA-processing protein 7 like protein A

0.54	GO:0001825	blastocyst formation
0.50	GO:0000028	ribosomal small subunit assembly
0.45	GO:0006364	rRNA processing
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0051028	mRNA transport
0.34	GO:0006405	RNA export from nucleus

0.50	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding

0.52	GO:0032545	CURI complex
0.52	GO:0034456	UTP-C complex
0.39	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

sp|Q9Y3A5|SBDS_HUMAN
Ribosome maturation protein SBDS
Search

SBDS

0.83	Shwachman-Bodian-Diamond syndrome

0.76	GO:0042256	mature ribosome assembly
0.57	GO:0048539	bone marrow development
0.55	GO:0030282	bone mineralization
0.54	GO:0001833	inner cell mass cell proliferation
0.54	GO:0030595	leukocyte chemotaxis
0.53	GO:0007052	mitotic spindle organization
0.49	GO:0006364	rRNA processing
0.46	GO:0031017	exocrine pancreas development
0.46	GO:0030851	granulocyte differentiation

0.50	GO:0043022	ribosome binding
0.49	GO:0008017	microtubule binding
0.46	GO:0019843	rRNA binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0000922	spindle pole
0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.39	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3A6|TMED5_HUMAN
Transmembrane emp24 domain-containing protein 5
Search

TMED5

0.96	Transmembrane emp24 protein transport domain containing 5

0.59	GO:0090161	Golgi ribbon formation
0.37	GO:0015031	protein transport
0.32	GO:0006355	regulation of transcription, DNA-templated

0.33	GO:0005515	protein binding
0.31	GO:0003676	nucleic acid binding

0.58	GO:0070971	endoplasmic reticulum exit site
0.57	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.55	GO:0005801	cis-Golgi network
0.40	GO:0005794	Golgi apparatus
0.39	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0098588	bounding membrane of organelle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3B1|PLD3B_HUMAN
PRELI domain containing protein 3B
Search

PRELID3B

0.96	PRELI domain containing protein 3B

0.46	GO:0015914	phospholipid transport
0.34	GO:1903955	positive regulation of protein targeting to mitochondrion

0.50

GO:1990050

phosphatidic acid transporter activity

0.79

GO:0005758

mitochondrial intermembrane space

sp|Q9Y3B2|EXOS1_HUMAN
Exosome complex component CSL4
Search

EXOSC1

0.77	Exosome component 1

0.35	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.35	GO:0043488	regulation of mRNA stability
0.35	GO:0006364	rRNA processing

0.58	GO:0003723	RNA binding
0.37	GO:0004532	exoribonuclease activity
0.34	GO:0005515	protein binding

0.78	GO:0000178	exosome (RNase complex)
0.50	GO:0031981	nuclear lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005737	cytoplasm

sp|Q9Y3B3|TMED7_HUMAN
Transmembrane emp24 domain-containing protein 7
Search

TMED7

0.92	Transmembrane p24 trafficking protein 7

0.61	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.54	GO:0005794	Golgi apparatus
0.54	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|Q9Y3B4|SF3B6_HUMAN
Splicing factor 3B subunit 6
Search

SF3B6

0.90	Pre-mRNA branch site protein p14

0.53	GO:0001825	blastocyst formation
0.51	GO:0000398	mRNA splicing, via spliceosome
0.40	GO:0006030	chitin metabolic process
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.40	GO:0008061	chitin binding
0.33	GO:0005515	protein binding

0.56	GO:0005689	U12-type spliceosomal complex
0.48	GO:0071011	precatalytic spliceosome
0.47	GO:0005686	U2 snRNP
0.47	GO:0071013	catalytic step 2 spliceosome
0.46	GO:0005684	U2-type spliceosomal complex
0.38	GO:0005576	extracellular region
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3B6|EMC9_HUMAN
ER membrane protein complex subunit 9
Search

EMC9

0.89	ER membrane protein complex subunit 9

0.37

GO:0005515

protein binding

0.83	GO:0072546	ER membrane protein complex
0.35	GO:0008537	proteasome activator complex

sp|Q9Y3B7|RM11_HUMAN
39S ribosomal protein L11, mitochondrial
Search

MRPL11

0.95	Mitochondrial ribosomal protein L11

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:0000027	ribosomal large subunit assembly
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0019843	rRNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.54	GO:0005759	mitochondrial matrix
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3B8|ORN_HUMAN
Oligoribonuclease, mitochondrial
Search

REXO2

0.48	Oligoribonuclease, mitochondrial

0.75	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.33	GO:0009117	nucleotide metabolic process
0.33	GO:0035383	thioester metabolic process
0.32	GO:0006732	coenzyme metabolic process

0.79	GO:0000175	3'-5'-exoribonuclease activity
0.51	GO:0003676	nucleic acid binding
0.33	GO:0047617	acyl-CoA hydrolase activity

0.57	GO:0005925	focal adhesion
0.52	GO:0005730	nucleolus
0.47	GO:0005739	mitochondrion
0.39	GO:0031970	organelle envelope lumen
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.1.13

GO:0000175

sp|Q9Y3B9|RRP15_HUMAN
RRP15-like protein
Search

RRP15

0.97	Ribosomal RNA processing 15 homolog

0.68	GO:0006364	rRNA processing
0.47	GO:0042273	ribosomal large subunit biogenesis

0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48

GO:0030687

preribosome, large subunit precursor

sp|Q9Y3C0|WASC3_HUMAN
WASH complex subunit 3
Search

WASHC3

0.96	WASH complex subunit 3

0.37

GO:0015031

protein transport

0.34

GO:0005515

protein binding

0.81	GO:0071203	WASH complex
0.39	GO:0005769	early endosome

sp|Q9Y3C1|NOP16_HUMAN
Nucleolar protein 16
Search

NOP16

0.83	Nucleolar protein 16

0.61

GO:0042273

ribosomal large subunit biogenesis

0.38

GO:0003723

RNA binding

0.73

GO:0005730

nucleolus

sp|Q9Y3C4|TPRKB_HUMAN
EKC/KEOPS complex subunit TPRKB
Search

TPRKB

0.94	EKC/KEOPS complex subunit TPRKB

0.36	GO:0008033	tRNA processing
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0090342	regulation of cell aging
0.33	GO:0000722	telomere maintenance via recombination
0.32	GO:0045944	positive regulation of transcription by RNA polymerase II
0.32	GO:0006351	transcription, DNA-templated

0.51	GO:0019901	protein kinase binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.53	GO:0000408	EKC/KEOPS complex
0.47	GO:0005829	cytosol
0.33	GO:0000781	chromosome, telomeric region

0.34

GO:0008138

sp|Q9Y3C5|RNF11_HUMAN
RING finger protein 11
Search

RNF11

0.93	Ring finger protein 11

0.80	GO:0051865	protein autoubiquitination
0.78	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.62	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.36	GO:0006486	protein glycosylation

0.73	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0061659	ubiquitin-like protein ligase activity
0.38	GO:0005515	protein binding
0.37	GO:0046872	metal ion binding
0.35	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0003677	DNA binding

0.72	GO:0000151	ubiquitin ligase complex
0.45	GO:0055037	recycling endosome
0.45	GO:0005769	early endosome
0.39	GO:0005634	nucleus
0.39	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.35	EC:2.4	GO:0016757
0.73	KEGG:R03876	GO:0004842

sp|Q9Y3C6|PPIL1_HUMAN
Peptidyl-prolyl cis-trans isomerase-like 1
Search

PPIL1

0.48	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.67	GO:0006457	protein folding

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.51	GO:0097718	disordered domain specific binding

0.49	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

0.72

GO:0003755

sp|Q9Y3C7|MED31_HUMAN
Mediator of RNA polymerase II transcription subunit 31
Search

MED31

0.71	Mediator of RNA polymerase II transcription subunit 31-B

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.54	GO:0048147	negative regulation of fibroblast proliferation
0.52	GO:0060173	limb development
0.36	GO:0016567	protein ubiquitination
0.32	GO:0055114	oxidation-reduction process

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.45	GO:0003713	transcription coactivator activity
0.36	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0005515	protein binding
0.33	GO:0047134	protein-disulfide reductase activity

0.77	GO:0016592	mediator complex
0.48	GO:0070847	core mediator complex
0.36	GO:0000151	ubiquitin ligase complex
0.32	GO:0005829	cytosol

0.33

EC:1.8.1.8

GO:0047134

sp|Q9Y3C8|UFC1_HUMAN
Ubiquitin-fold modifier-conjugating enzyme 1
Search

UFC1

0.89	Ubiquitin-fold modifier-conjugating enzyme 1

0.86	GO:0071569	protein ufmylation
0.67	GO:0034976	response to endoplasmic reticulum stress
0.41	GO:0016579	protein deubiquitination
0.40	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0042157	lipoprotein metabolic process
0.35	GO:0006869	lipid transport

0.86	GO:0071568	UFM1 transferase activity
0.41	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0005515	protein binding
0.35	GO:0008289	lipid binding

0.43	GO:0005737	cytoplasm
0.41	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0036459

sp|Q9Y3D0|MIP18_HUMAN
Mitotic spindle-associated MMXD complex subunit MIP18
Search

FAM96B

0.87	Mitotic spindle-associated MMXD complex subunit MIP18

0.69	GO:0007059	chromosome segregation
0.58	GO:0016226	iron-sulfur cluster assembly
0.39	GO:1901841	regulation of high voltage-gated calcium channel activity
0.35	GO:0007165	signal transduction

0.36	GO:0005515	protein binding
0.36	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0071817	MMXD complex
0.84	GO:0097361	CIA complex
0.67	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|Q9Y3D2|MSRB2_HUMAN
Methionine-R-sulfoxide reductase B2, mitochondrial
Search

MSRB2

0.88	'Methionine-R-sulfoxide reductase B2, mitochondrial'

0.77	GO:0030091	protein repair
0.71	GO:0006979	response to oxidative stress
0.53	GO:0030041	actin filament polymerization
0.53	GO:0055114	oxidation-reduction process
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.34	GO:0036211	protein modification process

0.79	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.53	GO:0033745	L-methionine-(R)-S-oxide reductase activity
0.49	GO:0003779	actin binding
0.44	GO:0008270	zinc ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0008113	peptide-methionine (S)-S-oxide reductase activity

0.43	GO:0005739	mitochondrion
0.39	GO:0005829	cytosol

0.79	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.79	KEGG:R07607	GO:0033743

sp|Q9Y3D3|RT16_HUMAN
28S ribosomal protein S16, mitochondrial
Search

MRPS16

0.97	Succinate dehydrogenase complex iron sulfur subunit B

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0035176	social behavior
0.35	GO:0032781	positive regulation of ATPase activity
0.35	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0031072	heat shock protein binding
0.33	GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
0.32	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.52	GO:0005759	mitochondrial matrix
0.46	GO:0005829	cytosol
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.34	GO:0005615	extracellular space
0.34	GO:0005654	nucleoplasm
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.2.1.96

GO:0033925

sp|Q9Y3D5|RT18C_HUMAN
28S ribosomal protein S18c, mitochondrial
Search

MRPS18C

0.96	Mitochondrial ribosomal protein S18C

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly
0.32	GO:0006629	lipid metabolic process
0.32	GO:0036211	protein modification process
0.32	GO:0055114	oxidation-reduction process

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.33	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005840	ribosome
0.51	GO:0005759	mitochondrial matrix
0.43	GO:0044445	cytosolic part
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004842

sp|Q9Y3D6|FIS1_HUMAN
Mitochondrial fission 1 protein
Search

FIS1

0.74	Fission, mitochondrial 1

0.84	GO:0000266	mitochondrial fission
0.56	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration
0.56	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.56	GO:0051561	positive regulation of mitochondrial calcium ion concentration
0.55	GO:0090141	positive regulation of mitochondrial fission
0.55	GO:0001836	release of cytochrome c from mitochondria
0.55	GO:0090314	positive regulation of protein targeting to membrane
0.55	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.54	GO:0070584	mitochondrion morphogenesis
0.54	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway

0.48	GO:0005102	receptor binding
0.36	GO:0032403	protein complex binding
0.34	GO:0005198	structural molecule activity
0.33	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.32	GO:0008168	methyltransferase activity

0.74	GO:0005741	mitochondrial outer membrane
0.51	GO:0005779	integral component of peroxisomal membrane
0.51	GO:0032592	integral component of mitochondrial membrane
0.47	GO:0005783	endoplasmic reticulum
0.42	GO:0043234	protein complex
0.36	GO:0005923	bicellular tight junction
0.33	GO:0005886	plasma membrane

0.33

EC:3.6.1.19

GO:0047429

sp|Q9Y3D7|TIM16_HUMAN
Mitochondrial import inner membrane translocase subunit TIM16
Search

0.78	Mitochondrial import inner membrane translocase subunit 16

0.82	GO:0030150	protein import into mitochondrial matrix
0.42	GO:0001503	ossification
0.40	GO:0032780	negative regulation of ATPase activity
0.37	GO:2001234	negative regulation of apoptotic signaling pathway
0.35	GO:0071897	DNA biosynthetic process

0.35

GO:0005515

protein binding

0.82	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.40	GO:0031314	extrinsic component of mitochondrial inner membrane
0.39	GO:0005759	mitochondrial matrix

sp|Q9Y3D8|KAD6_HUMAN
Adenylate kinase isoenzyme 6
Search

AK6

0.97	Adenylate kinase isoenzyme 6

0.69	GO:0046939	nucleotide phosphorylation
0.36	GO:0046940	nucleoside monophosphate phosphorylation
0.35	GO:0015949	nucleobase-containing small molecule interconversion
0.34	GO:2000145	regulation of cell motility
0.34	GO:0006352	DNA-templated transcription, initiation
0.33	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.33	GO:0034599	cellular response to oxidative stress
0.33	GO:0015937	coenzyme A biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.78	GO:0004017	adenylate kinase activity
0.56	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0050145	nucleoside phosphate kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0004140	dephospho-CoA kinase activity

0.73	GO:0015030	Cajal body
0.46	GO:0005829	cytosol
0.38	GO:0005730	nucleolus
0.33	GO:0010494	cytoplasmic stress granule
0.30	GO:0016020	membrane

0.78	EC:2.7.4.3	GO:0004017
0.33	KEGG:R00130	GO:0004140

sp|Q9Y3D9|RT23_HUMAN
28S ribosomal protein S23, mitochondrial
Search

MRPS23

0.97	Mitochondrial ribosomal protein S23

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.37	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.62	GO:0031965	nuclear membrane
0.62	GO:0045111	intermediate filament cytoskeleton
0.61	GO:0005840	ribosome
0.52	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.37	GO:0019866	organelle inner membrane

sp|Q9Y3E0|GOT1B_HUMAN
Vesicle transport protein GOT1B
Search

GOLT1B

0.95	Golgi transport 1 homolog B

0.69	GO:0016192	vesicle-mediated transport
0.36	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0015031	protein transport
0.35	GO:0010469	regulation of receptor activity
0.34	GO:0007165	signal transduction
0.33	GO:0009082	branched-chain amino acid biosynthetic process

0.36	GO:0005184	neuropeptide hormone activity
0.34	GO:0004871	signal transducer activity
0.34	GO:0052655	L-valine transaminase activity
0.34	GO:0052654	L-leucine transaminase activity
0.34	GO:0052656	L-isoleucine transaminase activity

0.47	GO:0005783	endoplasmic reticulum
0.36	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.6.1.42	GO:0052655
0.34	KEGG:R01214	GO:0052655

sp|Q9Y3E1|HDGR3_HUMAN
Hepatoma-derived growth factor-related protein 3
Search

HDGFL3

0.97	Hepatoma-derived growth factor-related protein 3

0.78	GO:0007026	negative regulation of microtubule depolymerization
0.72	GO:0046785	microtubule polymerization
0.70	GO:0031175	neuron projection development
0.47	GO:0010469	regulation of receptor activity
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0030307	positive regulation of cell growth
0.43	GO:0008283	cell proliferation
0.37	GO:0036498	IRE1-mediated unfolded protein response
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0034504	protein localization to nucleus

0.67	GO:0008017	microtubule binding
0.51	GO:0001222	transcription corepressor binding
0.50	GO:0001106	RNA polymerase II transcription corepressor activity
0.48	GO:0008083	growth factor activity
0.42	GO:0008201	heparin binding
0.38	GO:0003682	chromatin binding
0.37	GO:0003677	DNA binding
0.37	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0001067	regulatory region nucleic acid binding
0.36	GO:1901265	nucleoside phosphate binding

0.66	GO:0005654	nucleoplasm
0.63	GO:0005576	extracellular region
0.62	GO:0005829	cytosol
0.48	GO:0017053	transcriptional repressor complex

sp|Q9Y3E2|BOLA1_HUMAN
BolA-like protein 1
Search

BOLA1

0.51	Transcriptional regulator BolA

0.43

GO:0051301

cell division

0.37

GO:0005515

protein binding

0.58	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|Q9Y3E5|PTH2_HUMAN
Peptidyl-tRNA hydrolase 2, mitochondrial
Search

PTRH2

0.88	Peptidyl-tRNA hydrolase 2, mitochondrial

0.41	GO:2000210	positive regulation of anoikis
0.40	GO:2000811	negative regulation of anoikis
0.37	GO:0010629	negative regulation of gene expression
0.35	GO:0006915	apoptotic process

0.76	GO:0004045	aminoacyl-tRNA hydrolase activity
0.35	GO:0005515	protein binding

0.46	GO:0005739	mitochondrion
0.37	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.76

EC:3.1.1.29

GO:0004045

sp|Q9Y3E7|CHMP3_HUMAN
Charged multivesicular body protein 3
Search

CHMP3

0.83	Charged multivesicular body protein 3

0.78	GO:0007034	vacuolar transport
0.43	GO:2000641	regulation of early endosome to late endosome transport
0.43	GO:1902188	positive regulation of viral release from host cell
0.43	GO:1902187	negative regulation of viral release from host cell
0.42	GO:0000920	cell separation after cytokinesis
0.42	GO:0051291	protein heterooligomerization
0.42	GO:0010824	regulation of centrosome duplication
0.41	GO:0090174	organelle membrane fusion
0.41	GO:0032509	endosome transport via multivesicular body sorting pathway
0.41	GO:0039702	viral budding via host ESCRT complex

0.43	GO:1990381	ubiquitin-specific protease binding
0.43	GO:0031210	phosphatidylcholine binding
0.40	GO:0042803	protein homodimerization activity
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.33	GO:0016874	ligase activity

0.44	GO:0005770	late endosome
0.44	GO:0010008	endosome membrane
0.41	GO:0036452	ESCRT complex
0.39	GO:0005829	cytosol
0.37	GO:0098796	membrane protein complex
0.36	GO:0030496	midbody
0.36	GO:0070062	extracellular exosome
0.36	GO:0005769	early endosome
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0016874

sp|Q9Y3F1|TA6P_HUMAN
Putative TAP2-associated 6.5 kDa polypeptide
Search

0.44	Putative TAP2-associated 6.5 kDa polypeptide

sp|Q9Y3F4|STRAP_HUMAN
Serine-threonine kinase receptor-associated protein
Search

STRAP

0.91	Serine-threonine kinase receptor-associated protein (Fragment)

0.60	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.59	GO:0030277	maintenance of gastrointestinal epithelium
0.59	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.58	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.58	GO:0010633	negative regulation of epithelial cell migration
0.57	GO:0050680	negative regulation of epithelial cell proliferation
0.56	GO:0000387	spliceosomal snRNP assembly
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0016310	phosphorylation

0.55	GO:0016301	kinase activity
0.52	GO:0005102	receptor binding
0.34	GO:0003723	RNA binding

0.59	GO:0032797	SMN complex
0.59	GO:0034719	SMN-Sm protein complex
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q9Y3I0|RTCB_HUMAN
tRNA-splicing ligase RtcB homolog
Search

RTCB

0.87	tRNA-splicing ligase RtcB homolog

0.80	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.52	GO:0001890	placenta development
0.51	GO:0001701	in utero embryonic development
0.34	GO:0006281	DNA repair

0.85	GO:0003972	RNA ligase (ATP) activity
0.53	GO:0017166	vinculin binding
0.51	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.35	GO:0008289	lipid binding
0.34	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0003676	nucleic acid binding

0.85	GO:0072669	tRNA-splicing ligase complex
0.47	GO:0005635	nuclear envelope
0.46	GO:0005789	endoplasmic reticulum membrane
0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.85

EC:6.5.1.3

GO:0003972

sp|Q9Y3I1|FBX7_HUMAN
F-box only protein 7
Search

FBXO7

0.96	F-box only protein 7

0.85	GO:1903599	positive regulation of autophagy of mitochondrion
0.85	GO:1903204	negative regulation of oxidative stress-induced neuron death
0.85	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.84	GO:0045620	negative regulation of lymphocyte differentiation
0.83	GO:0000422	autophagy of mitochondrion
0.83	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.79	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.78	GO:0010975	regulation of neuron projection development
0.76	GO:0006626	protein targeting to mitochondrion
0.76	GO:0031647	regulation of protein stability

0.78	GO:0043130	ubiquitin binding
0.76	GO:0031625	ubiquitin protein ligase binding
0.76	GO:0019901	protein kinase binding
0.71	GO:0046982	protein heterodimerization activity
0.43	GO:0004842	ubiquitin-protein transferase activity

0.86	GO:1990038	Lewy body corona
0.86	GO:0097462	Lewy neurite
0.86	GO:0097414	classical Lewy body
0.86	GO:0097409	glial cytoplasmic inclusion
0.86	GO:1990037	Lewy body core
0.74	GO:0000151	ubiquitin ligase complex
0.67	GO:0005829	cytosol
0.60	GO:0005634	nucleus
0.60	GO:0005739	mitochondrion
0.58	GO:0043234	protein complex

0.43

GO:0004842

sp|Q9Y3L3|3BP1_HUMAN
SH3 domain-binding protein 1
Search

SH3BP1

0.97	SH3 domain-binding protein 1

0.72	GO:0043547	positive regulation of GTPase activity
0.61	GO:0045198	establishment of epithelial cell apical/basal polarity
0.60	GO:0006911	phagocytosis, engulfment
0.59	GO:0043535	regulation of blood vessel endothelial cell migration
0.58	GO:0051058	negative regulation of small GTPase mediated signal transduction
0.58	GO:0007165	signal transduction
0.58	GO:0034329	cell junction assembly
0.57	GO:0030834	regulation of actin filament depolymerization
0.55	GO:0016477	cell migration
0.53	GO:0007015	actin filament organization

0.72	GO:0005096	GTPase activator activity
0.62	GO:0030215	semaphorin receptor binding
0.40	GO:0017124	SH3 domain binding
0.38	GO:0016791	phosphatase activity

0.61	GO:0001891	phagocytic cup
0.58	GO:0030027	lamellipodium
0.57	GO:0005923	bicellular tight junction
0.56	GO:0005912	adherens junction
0.56	GO:0000145	exocyst
0.50	GO:0005829	cytosol
0.46	GO:0005634	nucleus

0.38

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q9Y3L5|RAP2C_HUMAN
Ras-related protein Rap-2c
Search

RAP2C

0.95	RAP2C, member of RAS oncogene family

0.63	GO:0032486	Rap protein signal transduction
0.62	GO:0031954	positive regulation of protein autophosphorylation
0.58	GO:0030336	negative regulation of cell migration
0.57	GO:0061097	regulation of protein tyrosine kinase activity
0.55	GO:0090557	establishment of endothelial intestinal barrier
0.48	GO:0070527	platelet aggregation
0.46	GO:0030033	microvillus assembly
0.44	GO:0048814	regulation of dendrite morphogenesis
0.43	GO:0046328	regulation of JNK cascade
0.42	GO:0072659	protein localization to plasma membrane

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003713	transcription coactivator activity
0.44	GO:0019904	protein domain specific binding
0.38	GO:0000287	magnesium ion binding

0.61	GO:0055038	recycling endosome membrane
0.57	GO:0044291	cell-cell contact zone
0.55	GO:0005923	bicellular tight junction
0.51	GO:0005829	cytosol
0.47	GO:0070062	extracellular exosome
0.45	GO:0045121	membrane raft
0.44	GO:0005886	plasma membrane
0.38	GO:0030496	midbody
0.37	GO:0070821	tertiary granule membrane
0.35	GO:0035579	specific granule membrane

sp|Q9Y3M2|CBY1_HUMAN
Protein chibby homolog 1
Search

CBY1

0.80	Chibby family member 1, beta catenin antagonist

0.83	GO:0055007	cardiac muscle cell differentiation
0.82	GO:0045444	fat cell differentiation
0.80	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.76	GO:0060271	cilium assembly
0.48	GO:0051289	protein homotetramerization
0.46	GO:0008104	protein localization
0.43	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0046907	intracellular transport
0.42	GO:0070727	cellular macromolecule localization
0.41	GO:0042886	amide transport

0.47	GO:0008013	beta-catenin binding
0.45	GO:0042803	protein homodimerization activity

0.79	GO:0036064	ciliary basal body
0.50	GO:0005814	centriole
0.49	GO:0016607	nuclear speck
0.46	GO:0005802	trans-Golgi network
0.45	GO:0005741	mitochondrial outer membrane
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3M8|STA13_HUMAN
StAR-related lipid transfer protein 13
Search

STARD13

0.96	StAR related lipid transfer domain containing 13

0.60	GO:0097498	endothelial tube lumen extension
0.60	GO:0007165	signal transduction
0.58	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.56	GO:0043542	endothelial cell migration
0.38	GO:0060055	angiogenesis involved in wound healing
0.36	GO:0043547	positive regulation of GTPase activity
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.34	GO:0007049	cell cycle

0.70	GO:0008289	lipid binding
0.36	GO:0005096	GTPase activator activity
0.33	GO:0005515	protein binding

0.37	GO:0005811	lipid droplet
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0005829	cytosol

sp|Q9Y3M9|ZN337_HUMAN
Zinc finger protein 337
Search

0.61	Zinc finger protein 133

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.49	GO:0034968	histone lysine methylation
0.34	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.49	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.44	GO:0005730	nucleolus
0.36	GO:0016604	nuclear body
0.33	GO:0031965	nuclear membrane

0.49

GO:0018024

sp|Q9Y3N9|OR2W1_HUMAN
Olfactory receptor 2W1
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.33	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding

0.55	GO:0005886	plasma membrane
0.33	GO:0000786	nucleosome
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3P4|RHBD3_HUMAN
Rhomboid domain-containing protein 3
Search

RHBDD3

0.97	Rhomboid domain-containing protein 3

0.71	GO:0032815	negative regulation of natural killer cell activation
0.67	GO:0002673	regulation of acute inflammatory response
0.66	GO:0001889	liver development
0.63	GO:0045732	positive regulation of protein catabolic process
0.63	GO:0050708	regulation of protein secretion
0.63	GO:0000165	MAPK cascade
0.61	GO:0009410	response to xenobiotic stimulus
0.57	GO:0006508	proteolysis

0.65	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005515	protein binding

0.40	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.65

GO:0004252

sp|Q9Y3P8|SIT1_HUMAN
Signaling threshold-regulating transmembrane adapter 1
Search

SIT1

0.97	Signaling threshold-regulating transmembrane adapter 1

0.85	GO:0043029	T cell homeostasis
0.77	GO:0050863	regulation of T cell activation
0.61	GO:0007165	signal transduction
0.45	GO:0002250	adaptive immune response

0.67	GO:0019900	kinase binding
0.56	GO:0042169	SH2 domain binding

0.50	GO:0005886	plasma membrane
0.43	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q9Y3P9|RBGP1_HUMAN
Rab GTPase-activating protein 1
Search

RABGAP1

0.94	LOW QUALITY PROTEIN: rab GTPase-activating protein 1

0.74	GO:0043547	positive regulation of GTPase activity
0.66	GO:0007049	cell cycle
0.47	GO:0031338	regulation of vesicle fusion
0.42	GO:0006886	intracellular protein transport
0.37	GO:0032880	regulation of protein localization
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:1902017	regulation of cilium assembly

0.75	GO:0005096	GTPase activator activity
0.57	GO:0017137	Rab GTPase binding
0.36	GO:0004930	G-protein coupled receptor activity
0.34	GO:0015631	tubulin binding

0.49	GO:0005829	cytosol
0.42	GO:0012505	endomembrane system
0.37	GO:0005929	cilium
0.37	GO:0005815	microtubule organizing center
0.37	GO:0031410	cytoplasmic vesicle
0.35	GO:0005634	nucleus
0.34	GO:0005875	microtubule associated complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3Q0|NALD2_HUMAN
N-acetylated-alpha-linked acidic dipeptidase 2
Search

NAALAD2

0.94	N-acetylated-alpha-linked acidic dipeptidase 2

0.57	GO:0042135	neurotransmitter catabolic process
0.48	GO:0006508	proteolysis
0.35	GO:0008652	cellular amino acid biosynthetic process

0.65	GO:0050129	N-formylglutamate deformylase activity
0.55	GO:0004180	carboxypeptidase activity
0.39	GO:0016805	dipeptidase activity
0.37	GO:0008237	metallopeptidase activity
0.37	GO:0008239	dipeptidyl-peptidase activity
0.35	GO:0008236	serine-type peptidase activity
0.35	GO:0046872	metal ion binding

0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.65	EC:3.5.1.68	GO:0050129
0.65	KEGG:R00525	GO:0050129

sp|Q9Y3Q3|TMED3_HUMAN
Transmembrane emp24 domain-containing protein 3
Search

TMED3

0.88	Transmembrane p24 trafficking protein 3

0.67	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.58	GO:0005794	Golgi apparatus
0.57	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|Q9Y3Q4|HCN4_HUMAN
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Search

HCN4

0.84	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

0.79	GO:0002027	regulation of heart rate
0.73	GO:0071805	potassium ion transmembrane transport
0.72	GO:0034765	regulation of ion transmembrane transport
0.70	GO:0006814	sodium ion transport
0.60	GO:0086046	membrane depolarization during SA node cell action potential
0.59	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction
0.59	GO:0071321	cellular response to cGMP
0.58	GO:0071320	cellular response to cAMP
0.57	GO:0003254	regulation of membrane depolarization
0.56	GO:0098659	inorganic cation import across plasma membrane

0.79	GO:0030552	cAMP binding
0.77	GO:0005249	voltage-gated potassium channel activity
0.62	GO:0005248	voltage-gated sodium channel activity
0.60	GO:0005222	intracellular cAMP activated cation channel activity
0.51	GO:0042802	identical protein binding

0.60	GO:0098855	HCN channel complex
0.53	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0030424	axon
0.39	GO:0036477	somatodendritic compartment
0.38	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0044297	cell body
0.37	GO:0098793	presynapse
0.36	GO:0016323	basolateral plasma membrane

sp|Q9Y3Q7|ADA18_HUMAN
Disintegrin and metalloproteinase domain-containing protein 18
Search

0.91	Disintegrin and metalloproteinase domain-containing protein 5

0.60	GO:0006508	proteolysis
0.53	GO:0007229	integrin-mediated signaling pathway
0.52	GO:0007338	single fertilization
0.41	GO:0007283	spermatogenesis
0.40	GO:0008542	visual learning
0.39	GO:0030534	adult behavior
0.39	GO:0007155	cell adhesion
0.39	GO:0007275	multicellular organism development
0.38	GO:0030154	cell differentiation
0.37	GO:0010628	positive regulation of gene expression

0.70	GO:0004222	metalloendopeptidase activity
0.37	GO:0005178	integrin binding
0.35	GO:0046872	metal ion binding

0.38	GO:0009986	cell surface
0.35	GO:0043234	protein complex
0.34	GO:0001669	acrosomal vesicle
0.33	GO:0005887	integral component of plasma membrane

0.70

GO:0004222

sp|Q9Y3Q8|T22D4_HUMAN
TSC22 domain family protein 4
Search

TSC22D4

0.39	Putative transcriptional regulator

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0070236	negative regulation of activation-induced cell death of T cells
0.39	GO:0006970	response to osmotic stress
0.37	GO:0008101	decapentaplegic signaling pathway
0.37	GO:0036335	intestinal stem cell homeostasis
0.37	GO:0009996	negative regulation of cell fate specification
0.37	GO:0046843	dorsal appendage formation
0.37	GO:0002052	positive regulation of neuroblast proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.38	GO:0005515	protein binding
0.33	GO:0017095	heparan sulfate 6-O-sulfotransferase activity

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0017095

sp|Q9Y3R0|GRIP1_HUMAN
Glutamate receptor-interacting protein 1
Search

GRIP1

0.95	Glutamate receptor-interacting protein 1

0.83	GO:0016358	dendrite development
0.44	GO:0008104	protein localization
0.39	GO:0150012	positive regulation of neuron projection arborization
0.36	GO:0030521	androgen receptor signaling pathway
0.34	GO:0045893	positive regulation of transcription, DNA-templated
0.33	GO:0042886	amide transport
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0071702	organic substance transport
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.85	GO:0030159	receptor signaling complex scaffold activity
0.56	GO:0035259	glucocorticoid receptor binding
0.52	GO:0008022	protein C-terminus binding
0.36	GO:0050681	androgen receptor binding
0.35	GO:0008013	beta-catenin binding
0.35	GO:0003713	transcription coactivator activity
0.32	GO:0003735	structural constituent of ribosome

0.52	GO:0055037	recycling endosome
0.51	GO:0030425	dendrite
0.51	GO:0045121	membrane raft
0.41	GO:0005886	plasma membrane
0.38	GO:0098794	postsynapse
0.37	GO:0030054	cell junction
0.37	GO:0005783	endoplasmic reticulum
0.35	GO:0032279	asymmetric synapse
0.35	GO:0043025	neuronal cell body
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

sp|Q9Y3R4|NEUR2_HUMAN
Sialidase-2
Search

NEU2

0.97	Neuraminidase 2

0.64	GO:0001573	ganglioside metabolic process
0.62	GO:0046479	glycosphingolipid catabolic process
0.62	GO:0046514	ceramide catabolic process
0.59	GO:0051692	cellular oligosaccharide catabolic process
0.39	GO:0006516	glycoprotein catabolic process
0.35	GO:0010831	positive regulation of myotube differentiation
0.35	GO:0045663	positive regulation of myoblast differentiation
0.35	GO:0045471	response to ethanol

0.75	GO:0016997	alpha-sialidase activity
0.34	GO:0005515	protein binding

0.50	GO:0005829	cytosol
0.46	GO:1902494	catalytic complex
0.41	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0012505	endomembrane system
0.35	GO:0019866	organelle inner membrane
0.33	GO:0005886	plasma membrane

sp|Q9Y3R5|DOP2_HUMAN
Protein dopey-2
Search

DOPEY2

0.97	Dopey family member 2

0.79	GO:0050890	cognition
0.66	GO:0006895	Golgi to endosome transport

0.34

GO:0008270

zinc ion binding

0.62	GO:0005802	trans-Golgi network
0.59	GO:0005768	endosome
0.55	GO:0005829	cytosol
0.40	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q9Y3S1|WNK2_HUMAN
Serine/threonine-protein kinase WNK2
Search

WNK2

0.85	WNK lysine deficient protein kinase 2

0.74	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.69	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.68	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.66	GO:2000021	regulation of ion homeostasis
0.65	GO:0046777	protein autophosphorylation
0.64	GO:0008285	negative regulation of cell proliferation
0.45	GO:0035556	intracellular signal transduction

0.70	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

sp|Q9Y3S2|ZN330_HUMAN
Zinc finger protein 330
Search

ZNF330

0.52	Zinc finger protein 330

0.37	GO:0035167	larval lymph gland hemopoiesis
0.34	GO:0048741	skeletal muscle fiber development
0.34	GO:0007605	sensory perception of sound

0.63	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.55	GO:0030496	midbody
0.53	GO:0000775	chromosome, centromeric region
0.48	GO:0031974	membrane-enclosed lumen

sp|Q9Y3T6|R3HC1_HUMAN
R3H and coiled-coil domain-containing protein 1
Search

R3HCC1

0.97	R3H and coiled-coil domain-containing protein 1

0.34

GO:0006281

DNA repair

0.50	GO:0003676	nucleic acid binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.51

GO:0035145

exon-exon junction complex

sp|Q9Y3T9|NOC2L_HUMAN
Nucleolar complex protein 2 homolog
Search

NOC2L

0.86	NOC2 like nucleolar associated transcriptional repressor

0.85	GO:0035067	negative regulation of histone acetylation
0.85	GO:0002903	negative regulation of B cell apoptotic process
0.80	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.79	GO:0034644	cellular response to UV
0.76	GO:0000122	negative regulation of transcription by RNA polymerase II
0.74	GO:0031497	chromatin assembly
0.61	GO:0042273	ribosomal large subunit biogenesis
0.45	GO:0006915	apoptotic process
0.41	GO:1901796	regulation of signal transduction by p53 class mediator
0.39	GO:0006351	transcription, DNA-templated

0.84	GO:0070491	repressing transcription factor binding
0.80	GO:0003714	transcription corepressor activity
0.78	GO:0042393	histone binding
0.78	GO:0031491	nucleosome binding
0.40	GO:0002039	p53 binding
0.39	GO:0003723	RNA binding

0.72	GO:0005730	nucleolus
0.70	GO:0030691	Noc2p-Noc3p complex
0.69	GO:0030690	Noc1p-Noc2p complex
0.69	GO:0005654	nucleoplasm
0.64	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q9Y3U8|RL36_HUMAN
60S ribosomal protein L36
Search

RPL36

0.70	60S ribosomal protein L36 pseudogene

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.43	GO:0007420	brain development
0.42	GO:0051726	regulation of cell cycle
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.35	GO:0070840	dynein complex binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0008134	transcription factor binding
0.32	GO:0016491	oxidoreductase activity

0.60	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.46	GO:0005844	polysome
0.43	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.32

GO:0016491

sp|Q9Y3V2|RWDD3_HUMAN
RWD domain-containing protein 3
Search

RWDD3

0.97	RWD domain-containing protein 3

0.88	GO:1902073	positive regulation of hypoxia-inducible factor-1alpha signaling pathway
0.86	GO:0033235	positive regulation of protein sumoylation
0.84	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.37

GO:0005515

protein binding

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

sp|Q9Y3X0|CCDC9_HUMAN
Coiled-coil domain-containing protein 9
Search

CCDC9

0.97	Coiled-coil domain-containing protein 9

0.61	GO:0038178	complement component C5a signaling pathway
0.50	GO:0006935	chemotaxis

0.61	GO:0004878	complement component C5a receptor activity
0.51	GO:0003723	RNA binding
0.51	GO:0004930	G-protein coupled receptor activity
0.48	GO:0005515	protein binding

0.30

GO:0044425

membrane part

sp|Q9Y3Y2|CHTOP_HUMAN
Chromatin target of PRMT1 protein
Search

CHTOP

0.97	Chromatin target of PRMT1 protein isoform 1

0.85	GO:0051096	positive regulation of helicase activity
0.83	GO:0031062	positive regulation of histone methylation
0.78	GO:0032781	positive regulation of ATPase activity
0.77	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0008284	positive regulation of cell proliferation
0.73	GO:0051028	mRNA transport
0.72	GO:0006405	RNA export from nucleus
0.52	GO:0010467	gene expression
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.85	GO:0008327	methyl-CpG binding
0.41	GO:0003723	RNA binding
0.39	GO:0005515	protein binding
0.37	GO:0005509	calcium ion binding

0.81	GO:0000346	transcription export complex
0.78	GO:0016607	nuclear speck
0.76	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0005730	nucleolus

sp|Q9Y3Y4|PYGO1_HUMAN
Pygopus homolog 1
Search

PYGO1

0.97	Pygopus like protein 1

0.66	GO:0007289	spermatid nucleus differentiation
0.62	GO:0001822	kidney development
0.62	GO:0002244	hematopoietic progenitor cell differentiation
0.60	GO:0009791	post-embryonic development
0.59	GO:0016055	Wnt signaling pathway
0.59	GO:0034504	protein localization to nucleus
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0035563	positive regulation of chromatin binding
0.44	GO:0033599	regulation of mammary gland epithelial cell proliferation
0.43	GO:0051569	regulation of histone H3-K4 methylation

0.61	GO:0140034	methylation-dependent protein binding
0.61	GO:0042393	histone binding
0.54	GO:0046872	metal ion binding
0.45	GO:0035034	histone acetyltransferase regulator activity
0.41	GO:0003682	chromatin binding
0.34	GO:0030971	receptor tyrosine kinase binding

0.49	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.37	GO:0044446	intracellular organelle part
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y3Z3|SAMH1_HUMAN
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Search

SAMHD1

0.97	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

0.86	GO:0046061	dATP catabolic process
0.85	GO:0006203	dGTP catabolic process
0.83	GO:0051289	protein homotetramerization
0.77	GO:0051607	defense response to virus
0.72	GO:0045088	regulation of innate immune response
0.67	GO:0090501	RNA phosphodiester bond hydrolysis
0.42	GO:0044830	modulation by host of viral RNA genome replication
0.40	GO:1903901	negative regulation of viral life cycle
0.38	GO:0045893	positive regulation of transcription, DNA-templated

0.87	GO:0032560	guanyl deoxyribonucleotide binding
0.85	GO:0008832	dGTPase activity
0.72	GO:0042802	identical protein binding
0.68	GO:0004540	ribonuclease activity
0.62	GO:0008270	zinc ion binding
0.58	GO:0003723	RNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0005654	nucleoplasm
0.54	GO:0005886	plasma membrane

0.85	EC:3.1.5.1	GO:0008832
0.85	KEGG:R01856	GO:0008832

sp|Q9Y421|FA32A_HUMAN
Protein FAM32A
Search

0.49	GO:0006915	apoptotic process
0.45	GO:0007049	cell cycle
0.38	GO:0035646	endosome to melanosome transport
0.38	GO:0032438	melanosome organization
0.37	GO:0006886	intracellular protein transport
0.37	GO:0016192	vesicle-mediated transport

0.37	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.71	GO:0005730	nucleolus
0.38	GO:0030131	clathrin adaptor complex
0.35	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y426|C2CD2_HUMAN
C2 domain-containing protein 2
Search

C2CD2

0.97	C2 calcium-dependent domain containing 2

0.41	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q9Y442|CV024_HUMAN
Uncharacterized protein C22orf24
Search

sp|Q9Y446|PKP3_HUMAN
Plakophilin-3
Search

PKP3

0.96	Putative neural adherens junction protein plakophilin

0.77	GO:0098609	cell-cell adhesion
0.62	GO:0002159	desmosome assembly
0.60	GO:1902373	negative regulation of mRNA catabolic process
0.58	GO:0072659	protein localization to plasma membrane
0.37	GO:0070268	cornification
0.37	GO:0006417	regulation of translation
0.36	GO:0010172	embryonic body morphogenesis
0.35	GO:0032970	regulation of actin filament-based process
0.35	GO:0051493	regulation of cytoskeleton organization
0.34	GO:0042147	retrograde transport, endosome to Golgi

0.61	GO:0045294	alpha-catenin binding
0.61	GO:0098641	cadherin binding involved in cell-cell adhesion
0.52	GO:0019899	enzyme binding
0.39	GO:0045182	translation regulator activity
0.35	GO:0003723	RNA binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0019215	intermediate filament binding
0.33	GO:0032947	protein complex scaffold activity

0.85	GO:0030057	desmosome
0.61	GO:1990124	messenger ribonucleoprotein complex
0.61	GO:0005634	nucleus
0.58	GO:0005913	cell-cell adherens junction
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005886	plasma membrane
0.35	GO:0030906	retromer, cargo-selective complex
0.33	GO:0005829	cytosol
0.33	GO:0014704	intercalated disc

sp|Q9Y448|SKAP_HUMAN
Small kinetochore-associated protein
Search

KNSTRN

0.92	Kinetochore localized astrin/SPAG5 binding protein

0.85	GO:0051988	regulation of attachment of spindle microtubules to kinetochore
0.81	GO:0007051	spindle organization
0.73	GO:0007059	chromosome segregation
0.70	GO:0140014	mitotic nuclear division
0.60	GO:0051276	chromosome organization

0.78	GO:0000776	kinetochore
0.77	GO:0035371	microtubule plus-end
0.71	GO:0072686	mitotic spindle
0.61	GO:0005829	cytosol

sp|Q9Y450|HBS1L_HUMAN
HBS1-like protein
Search

HBS1L

0.86	HBS1 like translational GTPase

0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0007165	signal transduction

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003746	translation elongation factor activity
0.34	GO:0005515	protein binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.36	GO:0070062	extracellular exosome
0.35	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

EC:1.2.1

GO:0016620

sp|Q9Y458|TBX22_HUMAN
T-box transcription factor TBX22
Search

TBX22

0.96	T-box transcription factor TBX22

0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0048701	embryonic cranial skeleton morphogenesis
0.38	GO:0072001	renal system development

0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.45	GO:0001106	RNA polymerase II transcription corepressor activity
0.43	GO:0000987	proximal promoter sequence-specific DNA binding
0.42	GO:0042803	protein homodimerization activity
0.41	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.43	GO:0017053	transcriptional repressor complex
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q9Y462|ZN711_HUMAN
Zinc finger protein 711
Search

ZNF711

0.67	Zinc finger protein 711

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0006351	transcription, DNA-templated
0.32	GO:0007275	multicellular organism development

0.53	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.34	GO:0060388	vitelline envelope
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9Y463|DYR1B_HUMAN
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
Search

DYRK1B

0.92	Dual specificity tyrosine-phosphorylation-regulated kinase 1B

0.69	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0046777	protein autophosphorylation
0.53	GO:0060612	adipose tissue development
0.52	GO:0007520	myoblast fusion
0.48	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010628	positive regulation of gene expression
0.47	GO:0010557	positive regulation of macromolecule biosynthetic process
0.47	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0001706	endoderm formation
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.69	GO:0004713	protein tyrosine kinase activity
0.63	GO:0004674	protein serine/threonine kinase activity
0.61	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0003713	transcription coactivator activity
0.38	GO:0048156	tau protein binding
0.37	GO:0043621	protein self-association
0.36	GO:0042802	identical protein binding

0.44	GO:0005634	nucleus
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.36	GO:0005856	cytoskeleton
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0044446	intracellular organelle part
0.34	GO:0099512	supramolecular fiber
0.33	GO:0005737	cytoplasm

0.69

EC:2.7.10

GO:0004713

sp|Q9Y466|NR2E1_HUMAN
Nuclear receptor subfamily 2 group E member 1
Search

NR2E1

0.96	Nuclear receptor TLX

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0060164	regulation of timing of neuron differentiation
0.60	GO:0021764	amygdala development
0.59	GO:0021960	anterior commissure morphogenesis
0.59	GO:0048712	negative regulation of astrocyte differentiation
0.58	GO:0002118	aggressive behavior
0.58	GO:0021819	layer formation in cerebral cortex
0.58	GO:0021542	dentate gyrus development
0.58	GO:0021895	cerebral cortex neuron differentiation
0.58	GO:0097659	nucleic acid-templated transcription

0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0042826	histone deacetylase binding
0.32	GO:0008061	chitin binding
0.32	GO:0015631	tubulin binding

0.61	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q9Y467|SALL2_HUMAN
Sal-like protein 2
Search

SALL2

0.97	Spalt like transcription factor 2

0.57	GO:0021915	neural tube development
0.56	GO:0001654	eye development
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0007165	signal transduction
0.40	GO:0021891	olfactory bulb interneuron development
0.39	GO:0035137	hindlimb morphogenesis
0.39	GO:0045879	negative regulation of smoothened signaling pathway
0.39	GO:0035136	forelimb morphogenesis

0.56	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0044212	transcription regulatory region DNA binding
0.53	GO:1990837	sequence-specific double-stranded DNA binding
0.39	GO:0046872	metal ion binding
0.38	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
0.34	GO:0005515	protein binding

0.58	GO:0090545	CHD-type complex
0.57	GO:0090568	nuclear transcriptional repressor complex
0.56	GO:0000118	histone deacetylase complex

0.38

EC:2.1.1.62

GO:0016422

sp|Q9Y468|LMBL1_HUMAN
Lethal(3)malignant brain tumor-like protein 1
Search

0.83	L3MBTL1, histone methyl-lysine binding protein

0.61	GO:0043249	erythrocyte maturation
0.60	GO:0030225	macrophage differentiation
0.60	GO:0030851	granulocyte differentiation
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.49	GO:0043233	organelle lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part

sp|Q9Y471|CMAH_HUMAN
Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase
Search

0.97	Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase

0.53	GO:0046381	CMP-N-acetylneuraminate metabolic process
0.53	GO:0006054	N-acetylneuraminate metabolic process
0.52	GO:0055114	oxidation-reduction process
0.43	GO:0030111	regulation of Wnt signaling pathway
0.35	GO:0048741	skeletal muscle fiber development
0.34	GO:0007605	sensory perception of sound
0.34	GO:0006313	transposition, DNA-mediated
0.34	GO:0015074	DNA integration

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.67	GO:0030338	CMP-N-acetylneuraminate monooxygenase activity
0.41	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.40	GO:0005737	cytoplasm
0.40	GO:0005856	cytoskeleton
0.38	GO:0005634	nucleus
0.36	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.67

EC:1.14.18.2

GO:0030338

sp|Q9Y473|ZN175_HUMAN
Zinc finger protein 175
Search

ZNF175

0.86	LOW QUALITY PROTEIN: zinc finger protein 41

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.47	GO:0006366	transcription by RNA polymerase II
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0051607	defense response to virus

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.36	GO:0005515	protein binding

0.47	GO:0045111	intermediate filament cytoskeleton
0.44	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.35	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y478|AAKB1_HUMAN
5'-AMP-activated protein kinase subunit beta-1
Search

PRKAB1

0.97	5'AMP-activated protein kinase beta-1 non-catalytic subunit

0.61	GO:0035878	nail development
0.57	GO:0016310	phosphorylation
0.51	GO:0010628	positive regulation of gene expression
0.46	GO:0036211	protein modification process
0.44	GO:0044267	cellular protein metabolic process
0.41	GO:0051291	protein heterooligomerization
0.38	GO:0006633	fatty acid biosynthetic process
0.37	GO:0050790	regulation of catalytic activity
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0016241	regulation of macroautophagy

0.59	GO:0016301	kinase activity
0.47	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.45	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0019901	protein kinase binding
0.39	GO:0060089	molecular transducer activity
0.37	GO:0042802	identical protein binding
0.34	GO:0004623	phospholipase A2 activity
0.33	GO:0005509	calcium ion binding

0.46	GO:0005634	nucleus
0.44	GO:0031588	nucleotide-activated protein kinase complex
0.35	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.33	GO:0005576	extracellular region
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.47

EC:2.7.1

GO:0016773

sp|Q9Y483|MTF2_HUMAN
Metal-response element-binding transcription factor 2
Search

MTF2

0.95	Novel protein containing a PHD-finger domain

0.61	GO:0061086	negative regulation of histone H3-K27 methylation
0.60	GO:0061087	positive regulation of histone H3-K27 methylation
0.59	GO:0007379	segment specification
0.57	GO:1990823	response to leukemia inhibitory factor
0.56	GO:0019827	stem cell population maintenance
0.56	GO:0048863	stem cell differentiation
0.54	GO:0071345	cellular response to cytokine stimulus
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0016569	covalent chromatin modification

0.57	GO:0035064	methylated histone binding
0.54	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.35	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.32	GO:0003735	structural constituent of ribosome

0.57	GO:0035098	ESC/E(Z) complex
0.56	GO:0005925	focal adhesion
0.40	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q9Y484|WIPI4_HUMAN
WD repeat domain phosphoinositide-interacting protein 4
Search

WDR45

0.94	WD repeat domain phosphoinositide-interacting protein 4

0.77	GO:0006914	autophagy
0.47	GO:0061726	mitochondrion disassembly
0.46	GO:0007033	vacuole organization
0.45	GO:0006497	protein lipidation
0.43	GO:0070925	organelle assembly
0.42	GO:0034613	cellular protein localization

0.47	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.46	GO:0032266	phosphatidylinositol-3-phosphate binding
0.34	GO:0046983	protein dimerization activity

0.47	GO:0034045	phagophore assembly site membrane
0.44	GO:0019898	extrinsic component of membrane
0.42	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y485|DMXL1_HUMAN
DmX-like protein 1
Search

DMXL1

0.90	Dmx like 1

0.81	GO:0007035	vacuolar acidification
0.79	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly

0.51

GO:0017137

Rab GTPase binding

0.84	GO:0043291	RAVE complex
0.52	GO:0008021	synaptic vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y487|VPP2_HUMAN
V-type proton ATPase 116 kDa subunit a isoform 2
Search

ATP6V0A2

0.58	V-type proton ATPase subunit a

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.58	GO:0036295	cellular response to increased oxygen levels
0.53	GO:0030003	cellular cation homeostasis
0.52	GO:0098771	inorganic ion homeostasis
0.50	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.45	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.45	GO:0006754	ATP biosynthetic process
0.38	GO:0016241	regulation of macroautophagy
0.37	GO:0007039	protein catabolic process in the vacuole
0.36	GO:0016236	macroautophagy

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.51	GO:0051117	ATPase binding
0.48	GO:0036442	proton-exporting ATPase activity
0.45	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism

0.80	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain
0.56	GO:0001669	acrosomal vesicle
0.49	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.40	GO:0005886	plasma membrane
0.38	GO:0010008	endosome membrane
0.38	GO:0005765	lysosomal membrane
0.36	GO:0016607	nuclear speck
0.36	GO:0045177	apical part of cell
0.36	GO:0030670	phagocytic vesicle membrane
0.35	GO:0005794	Golgi apparatus

sp|Q9Y490|TLN1_HUMAN
Talin-1
Search

TLN2

0.87

Talin

0.83	GO:0007016	cytoskeletal anchoring at plasma membrane
0.72	GO:0007155	cell adhesion
0.51	GO:0061386	closure of optic fissure
0.49	GO:0055013	cardiac muscle cell development
0.49	GO:0045214	sarcomere organization
0.42	GO:0033622	integrin activation
0.42	GO:0034329	cell junction assembly
0.40	GO:0030866	cortical actin cytoskeleton organization
0.40	GO:0007229	integrin-mediated signaling pathway
0.35	GO:0045216	cell-cell junction organization

0.78	GO:0051015	actin filament binding
0.75	GO:0005200	structural constituent of cytoskeleton
0.42	GO:0017166	vinculin binding
0.42	GO:0030274	LIM domain binding
0.41	GO:0001786	phosphatidylserine binding
0.41	GO:0005178	integrin binding
0.40	GO:0045296	cadherin binding
0.39	GO:0035091	phosphatidylinositol binding

0.81	GO:0001726	ruffle
0.80	GO:0005925	focal adhesion
0.67	GO:0005856	cytoskeleton
0.36	GO:0045202	synapse
0.36	GO:0005916	fascia adherens
0.36	GO:0031256	leading edge membrane
0.36	GO:0031253	cell projection membrane
0.35	GO:0009986	cell surface
0.35	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

sp|Q9Y493|ZAN_HUMAN
Zonadhesin
Search

ZAN

0.67	LOW QUALITY PROTEIN: zonadhesin

0.46	GO:0007339	binding of sperm to zona pellucida
0.44	GO:0007155	cell adhesion
0.35	GO:0010469	regulation of receptor activity
0.34	GO:2000359	regulation of binding of sperm to zona pellucida

0.39	GO:0050840	extracellular matrix binding
0.36	GO:0005128	erythropoietin receptor binding
0.35	GO:0005179	hormone activity

0.38	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q9Y496|KIF3A_HUMAN
Kinesin-like protein KIF3A
Search

sp|Q9Y4A0|JERKL_HUMAN
Jerky protein homolog-like
Search

0.94	tigger transposable element-derived protein 2

0.36	GO:0007417	central nervous system development
0.34	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.33	GO:0015074	DNA integration
0.32	GO:0016310	phosphorylation
0.31	GO:0006351	transcription, DNA-templated

0.54	GO:0003677	DNA binding
0.39	GO:0003729	mRNA binding
0.34	GO:0004519	endonuclease activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016301	kinase activity
0.32	GO:0005515	protein binding

0.39	GO:0005634	nucleus
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005737	cytoplasm

sp|Q9Y4A5|TRRAP_HUMAN
Transformation/transcription domain-associated protein
Search

TRRAP

0.88	transformation/transcription domain-associated protein isoform X9

0.78	GO:0016573	histone acetylation
0.56	GO:0016310	phosphorylation
0.51	GO:0016578	histone deubiquitination
0.42	GO:0006281	DNA repair
0.41	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:1904837	beta-catenin-TCF complex assembly
0.34	GO:0007093	mitotic cell cycle checkpoint
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.58	GO:0016301	kinase activity
0.48	GO:0003712	transcription cofactor activity
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0005515	protein binding

0.76	GO:0000123	histone acetyltransferase complex
0.51	GO:0000812	Swr1 complex
0.48	GO:0090575	RNA polymerase II transcription factor complex
0.48	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.47	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.35

GO:0036459

sp|Q9Y4A8|NF2L3_HUMAN
Nuclear factor erythroid 2-related factor 3
Search

NFE2L3

0.96	Nuclear factor, erythroid 2 like 3

0.65	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0006351	transcription, DNA-templated
0.52	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0008359	regulation of bicoid mRNA localization
0.37	GO:0051663	oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
0.36	GO:0008103	oocyte microtubule cytoskeleton polarization
0.36	GO:0060465	pharynx development
0.36	GO:0007317	regulation of pole plasm oskar mRNA localization
0.36	GO:0045451	pole plasm oskar mRNA localization

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0003713	transcription coactivator activity
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.36	GO:0005703	polytene chromosome puff
0.30	GO:0016020	membrane

sp|Q9Y4A9|O10H1_HUMAN
Olfactory receptor 10H1
Search

0.97	Olfactory receptor family 10 subfamily H member 1

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0007210	serotonin receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.59	GO:0099589	serotonin receptor activity
0.54	GO:0030594	neurotransmitter receptor activity
0.32	GO:0003676	nucleic acid binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y4B4|ARIP4_HUMAN
Helicase ARIP4
Search

RAD54L2

0.93	RAD54 like 2 (S. cerevisiae)

0.38	GO:0000733	DNA strand renaturation
0.38	GO:0008340	determination of adult lifespan
0.37	GO:0010212	response to ionizing radiation
0.37	GO:0000724	double-strand break repair via homologous recombination
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0042493	response to drug

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0036310	annealing helicase activity
0.37	GO:0019901	protein kinase binding
0.36	GO:0003712	transcription cofactor activity
0.34	GO:0016887	ATPase activity

0.37	GO:0016607	nuclear speck
0.34	GO:0043234	protein complex

0.34

GO:0016887

sp|Q9Y4B5|MTCL1_HUMAN
Microtubule cross-linking factor 1
Search

MTCL1

0.96	Microtubule cross-linking factor 1

0.74	GO:0010506	regulation of autophagy
0.56	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.54	GO:0001578	microtubule bundle formation
0.50	GO:2000576	positive regulation of microtubule motor activity
0.50	GO:0090314	positive regulation of protein targeting to membrane

0.60	GO:0008017	microtubule binding
0.55	GO:0042803	protein homodimerization activity
0.37	GO:0003723	RNA binding

0.73	GO:0005615	extracellular space
0.66	GO:0030496	midbody
0.63	GO:0000922	spindle pole
0.58	GO:0097427	microtubule bundle
0.56	GO:0016327	apicolateral plasma membrane
0.55	GO:0016328	lateral plasma membrane
0.43	GO:0016324	apical plasma membrane
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y4B6|VPRBP_HUMAN
Protein VPRBP
Search

DCAF1

0.97	DDB1- and CUL4-associated factor 1

0.76	GO:1990245	histone H2A-T120 phosphorylation
0.73	GO:0016567	protein ubiquitination
0.73	GO:0035212	cell competition in a multicellular organism
0.67	GO:0030183	B cell differentiation
0.63	GO:0000122	negative regulation of transcription by RNA polymerase II
0.62	GO:0033151	V(D)J recombination
0.37	GO:0016032	viral process
0.36	GO:0006351	transcription, DNA-templated

0.76	GO:1990244	histone kinase activity (H2A-T120 specific)
0.71	GO:0030331	estrogen receptor binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.67	GO:0001650	fibrillar center
0.65	GO:0008180	COP9 signalosome
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9Y4C0|NRX3A_HUMAN
Neurexin-3
Search

NRXN3

0.83	Neurexin-3-beta

0.46	GO:0007416	synapse assembly
0.45	GO:0099643	signal release from synapse
0.45	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.44	GO:0006836	neurotransmitter transport
0.43	GO:0001505	regulation of neurotransmitter levels
0.41	GO:0051649	establishment of localization in cell
0.41	GO:0065009	regulation of molecular function
0.40	GO:0007155	cell adhesion
0.39	GO:0071625	vocalization behavior
0.39	GO:0035176	social behavior

0.47	GO:0005246	calcium channel regulator activity
0.40	GO:0097109	neuroligin family protein binding
0.38	GO:0050839	cell adhesion molecule binding
0.35	GO:0004872	receptor activity
0.35	GO:0046872	metal ion binding
0.33	GO:0004871	signal transducer activity

0.44	GO:0098793	presynapse
0.39	GO:0043234	protein complex
0.35	GO:0005887	integral component of plasma membrane

sp|Q9Y4C1|KDM3A_HUMAN
Lysine-specific demethylase 3A
Search

KDM3A

0.97	Lysine-specific demethylase 3A

0.77	GO:0036123	histone H3-K9 dimethylation
0.76	GO:0046293	formaldehyde biosynthetic process
0.75	GO:0007290	spermatid nucleus elongation
0.74	GO:0033169	histone H3-K9 demethylation
0.73	GO:0051573	negative regulation of histone H3-K9 methylation
0.72	GO:2000036	regulation of stem cell population maintenance
0.70	GO:0030521	androgen receptor signaling pathway
0.70	GO:2000736	regulation of stem cell differentiation
0.69	GO:1990830	cellular response to leukemia inhibitory factor
0.62	GO:0045944	positive regulation of transcription by RNA polymerase II

0.74	GO:0032454	histone demethylase activity (H3-K9 specific)
0.71	GO:0050681	androgen receptor binding
0.71	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.55	GO:0031490	chromatin DNA binding
0.53	GO:0008168	methyltransferase activity
0.53	GO:0005506	iron ion binding
0.52	GO:0003700	DNA binding transcription factor activity
0.42	GO:0051213	dioxygenase activity
0.31	GO:0016209	antioxidant activity
0.31	GO:0051287	NAD binding

0.58	GO:0005654	nucleoplasm
0.50	GO:0000785	chromatin
0.44	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0008168

sp|Q9Y4C2|TCAF1_HUMAN
TRPM8 channel-associated factor 1
Search

TCAF1

0.93	TRPM8 channel-associated factor homolog

0.74	GO:1901529	positive regulation of anion channel activity
0.71	GO:0090314	positive regulation of protein targeting to membrane
0.66	GO:0030336	negative regulation of cell migration
0.60	GO:0002244	hematopoietic progenitor cell differentiation
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.68	GO:0044325	ion channel binding
0.43	GO:0043565	sequence-specific DNA binding
0.42	GO:0003700	DNA binding transcription factor activity

0.49	GO:0005886	plasma membrane
0.42	GO:0030054	cell junction

sp|Q9Y4C4|MFHA1_HUMAN
Malignant fibrous histiocytoma-amplified sequence 1
Search

0.59	GO:0007165	signal transduction
0.41	GO:0006013	mannose metabolic process
0.37	GO:0006468	protein phosphorylation
0.34	GO:0007089	traversing start control point of mitotic cell cycle
0.34	GO:0048478	replication fork protection
0.34	GO:0000076	DNA replication checkpoint
0.34	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.34	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter
0.33	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic

0.41	GO:0004559	alpha-mannosidase activity
0.40	GO:0005515	protein binding
0.39	GO:0030246	carbohydrate binding
0.37	GO:0004672	protein kinase activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0000175	3'-5'-exoribonuclease activity
0.33	GO:0004842	ubiquitin-protein transferase activity

0.54	GO:0005886	plasma membrane
0.34	GO:0030015	CCR4-NOT core complex
0.34	GO:0016593	Cdc73/Paf1 complex
0.34	GO:0000932	P-body
0.30	GO:0016021	integral component of membrane

0.41	EC:3.2.1.24	GO:0004559
0.33	KEGG:R03876	GO:0004842

sp|Q9Y4C5|CHST2_HUMAN
Carbohydrate sulfotransferase 2
Search

CHST2

0.54	Carbohydrate sulfotransferase 2

0.57	GO:0005975	carbohydrate metabolic process
0.56	GO:0006044	N-acetylglucosamine metabolic process
0.50	GO:0006790	sulfur compound metabolic process
0.38	GO:0006954	inflammatory response
0.38	GO:1903510	mucopolysaccharide metabolic process
0.36	GO:0006024	glycosaminoglycan biosynthetic process
0.35	GO:0007275	multicellular organism development
0.34	GO:0043436	oxoacid metabolic process
0.33	GO:0044249	cellular biosynthetic process

0.78

GO:0008146

sulfotransferase activity

0.70	GO:0000139	Golgi membrane
0.57	GO:0005802	trans-Golgi network
0.36	GO:0031300	intrinsic component of organelle membrane
0.30	GO:0016021	integral component of membrane

0.78

GO:0008146

sp|Q9Y4C8|RBM19_HUMAN
Probable RNA-binding protein 19
Search

RBM19

0.95	RNA binding motif protein 19

0.56	GO:0040019	positive regulation of embryonic development
0.43	GO:0048546	digestive tract morphogenesis

0.59

GO:0003723

RNA binding

0.52	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.36	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y4D1|DAAM1_HUMAN
Disheveled-associated activator of morphogenesis 1
Search

DAAM1

0.97	Disheveled-associated activator of morphogenesis 1-A

0.72	GO:0030036	actin cytoskeleton organization
0.42	GO:0030838	positive regulation of actin filament polymerization
0.42	GO:0060026	convergent extension
0.41	GO:0097435	supramolecular fiber organization
0.39	GO:0048715	negative regulation of oligodendrocyte differentiation
0.39	GO:0021516	dorsal spinal cord development
0.39	GO:2000050	regulation of non-canonical Wnt signaling pathway
0.38	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.37	GO:0007368	determination of left/right symmetry
0.37	GO:0021986	habenula development

0.76	GO:0017048	Rho GTPase binding
0.72	GO:0003779	actin binding
0.50	GO:0042802	identical protein binding
0.41	GO:0008017	microtubule binding

0.56	GO:0097517	contractile actin filament bundle
0.55	GO:0042641	actomyosin
0.54	GO:0036064	ciliary basal body
0.53	GO:0031514	motile cilium
0.48	GO:0005829	cytosol
0.43	GO:0005884	actin filament
0.42	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y4D2|DGLA_HUMAN
Sn1-specific diacylglycerol lipase alpha
Search

DAGLA

0.92	Diacylglycerol lipase alpha

0.65	GO:0071926	endocannabinoid signaling pathway
0.62	GO:0098921	retrograde trans-synaptic signaling by endocannabinoid
0.62	GO:0006629	lipid metabolic process
0.58	GO:0007216	G-protein coupled glutamate receptor signaling pathway
0.57	GO:0007405	neuroblast proliferation
0.56	GO:0006690	icosanoid metabolic process
0.52	GO:0042136	neurotransmitter biosynthetic process
0.46	GO:0032787	monocarboxylic acid metabolic process
0.46	GO:0044248	cellular catabolic process
0.45	GO:1901575	organic substance catabolic process

0.50	GO:0016787	hydrolase activity
0.34	GO:0046872	metal ion binding

0.60	GO:0043196	varicosity
0.54	GO:0045211	postsynaptic membrane
0.37	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

0.50

GO:0016787

sp|Q9Y4D7|PLXD1_HUMAN
Plexin-D1
Search

0.83	GO:0071526	semaphorin-plexin signaling pathway
0.65	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching
0.63	GO:0043542	endothelial cell migration
0.63	GO:0001569	branching involved in blood vessel morphogenesis
0.62	GO:0060976	coronary vasculature development
0.62	GO:0035904	aorta development
0.61	GO:0003151	outflow tract morphogenesis
0.61	GO:0032092	positive regulation of protein binding
0.61	GO:0003279	cardiac septum development
0.60	GO:0007416	synapse assembly

0.84	GO:0017154	semaphorin receptor activity
0.56	GO:0019904	protein domain specific binding

0.59	GO:0030027	lamellipodium
0.50	GO:0005887	integral component of plasma membrane
0.39	GO:0031256	leading edge membrane
0.39	GO:0031253	cell projection membrane

sp|Q9Y4D8|HECD4_HUMAN
Probable E3 ubiquitin-protein ligase HECTD4
Search

HECTD4

0.91	HECT domain containing E3 ubiquitin protein ligase 4

0.71	GO:0016567	protein ubiquitination
0.41	GO:0042593	glucose homeostasis
0.39	GO:0006006	glucose metabolic process
0.33	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.72	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0016874	ligase activity
0.46	GO:0061659	ubiquitin-like protein ligase activity

0.37	GO:0005737	cytoplasm
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.54	EC:6	GO:0016874
0.72	KEGG:R03876	GO:0004842

sp|Q9Y4E1|WAC2C_HUMAN
WASH complex subunit 2C
Search

0.91	WASH complex subunit 2

0.47	GO:0042147	retrograde transport, endosome to Golgi
0.41	GO:1990126	retrograde transport, endosome to plasma membrane
0.41	GO:2000813	negative regulation of barbed-end actin filament capping
0.41	GO:1900024	regulation of substrate adhesion-dependent cell spreading
0.39	GO:0015031	protein transport

0.46	GO:1905394	retromer complex binding
0.45	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.45	GO:0010314	phosphatidylinositol-5-phosphate binding
0.45	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.44	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.44	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.44	GO:0070273	phosphatidylinositol-4-phosphate binding
0.44	GO:0032266	phosphatidylinositol-3-phosphate binding

0.84	GO:0071203	WASH complex
0.48	GO:0031901	early endosome membrane
0.44	GO:0005829	cytosol
0.43	GO:0030904	retromer complex
0.39	GO:0005730	nucleolus
0.38	GO:0005886	plasma membrane

sp|Q9Y4E5|ZN451_HUMAN
E3 SUMO-protein ligase ZNF451
Search

ZNF451

0.97	Zinc finger protein 451

0.68	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter
0.66	GO:2000616	negative regulation of histone H3-K9 acetylation
0.63	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.61	GO:0016925	protein sumoylation

0.67	GO:0061665	SUMO ligase activity
0.64	GO:0001106	RNA polymerase II transcription corepressor activity
0.50	GO:0003676	nucleic acid binding
0.36	GO:0051087	chaperone binding
0.35	GO:0008270	zinc ion binding

0.49

GO:0005634

nucleus

sp|Q9Y4E6|WDR7_HUMAN
WD repeat-containing protein 7
Search

WDR7

0.94	WD repeat-containing protein 7

0.82

GO:0002244

hematopoietic progenitor cell differentiation

0.38

GO:0005515

protein binding

0.45	GO:0008021	synaptic vesicle
0.30	GO:0044425	membrane part

sp|Q9Y4E8|UBP15_HUMAN
Ubiquitin carboxyl-terminal hydrolase 15
Search

USP15

0.93	Ubiquitin carboxyl-terminal hydrolase 15

0.75	GO:0016579	protein deubiquitination
0.71	GO:0006511	ubiquitin-dependent protein catabolic process
0.58	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.56	GO:0030509	BMP signaling pathway
0.55	GO:0007179	transforming growth factor beta receptor signaling pathway
0.51	GO:0016570	histone modification

0.75	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.60	GO:0061649	ubiquitin modification-dependent histone binding
0.56	GO:0005160	transforming growth factor beta receptor binding
0.56	GO:0046332	SMAD binding
0.51	GO:0004197	cysteine-type endopeptidase activity
0.50	GO:0042802	identical protein binding

0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.35	GO:0005739	mitochondrion

0.75

GO:0036459

sp|Q9Y4F1|FARP1_HUMAN
FERM, RhoGEF and pleckstrin domain-containing protein 1
Search

FARP1

0.94	FERM, ARHGEF and pleckstrin domain-containing protein 1

0.75	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.42	GO:0048813	dendrite morphogenesis
0.42	GO:0007416	synapse assembly
0.39	GO:0035305	negative regulation of dephosphorylation

0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.63	GO:0008092	cytoskeletal protein binding
0.42	GO:0048365	Rac GTPase binding

0.67	GO:0005856	cytoskeleton
0.41	GO:0043197	dendritic spine
0.41	GO:0030175	filopodium
0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0030054	cell junction
0.38	GO:0005829	cytosol

sp|Q9Y4F3|MARF1_HUMAN
Meiosis arrest female protein 1
Search

MARF1

0.95	Meiosis regulator and mRNA stability factor 1

0.56	GO:0060255	regulation of macromolecule metabolic process
0.49	GO:0007143	female meiotic nuclear division
0.48	GO:0048477	oogenesis
0.47	GO:0010923	negative regulation of phosphatase activity
0.45	GO:0006302	double-strand break repair

0.59

GO:0003723

RNA binding

0.76	GO:0005777	peroxisome
0.44	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|Q9Y4F4|CREC1_HUMAN
Crescerin-1
Search

TOGARAM1

0.97	TOG array regulator of axonemal microtubules protein 1

0.85	GO:0031116	positive regulation of microtubule polymerization
0.48	GO:1905515	non-motile cilium assembly
0.48	GO:0035082	axoneme assembly

0.83	GO:0036064	ciliary basal body
0.73	GO:0005874	microtubule
0.36	GO:0005737	cytoplasm

sp|Q9Y4F5|C170B_HUMAN
Centrosomal protein of 170 kDa protein B
Search

CEP170B

0.91	Centrosomal protein of 170 kDa protein B

0.40	GO:0035023	regulation of Rho protein signal transduction
0.37	GO:0065009	regulation of molecular function
0.33	GO:0006468	protein phosphorylation

0.40	GO:0003676	nucleic acid binding
0.40	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005874	microtubule
0.45	GO:0005737	cytoplasm

0.34

GO:0004674

sp|Q9Y4F9|FA65B_HUMAN
Protein FAM65B
Search

RIPOR2

0.97	Rho family-interacting cell polarization regulator 2

0.85	GO:0048741	skeletal muscle fiber development
0.83	GO:1903904	negative regulation of establishment of T cell polarity
0.83	GO:1905872	negative regulation of protein localization to cell leading edge
0.82	GO:1904476	negative regulation of Ras GTPase binding
0.82	GO:0007605	sensory perception of sound
0.81	GO:2000405	negative regulation of T cell migration
0.80	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.80	GO:2000391	positive regulation of neutrophil extravasation
0.80	GO:1990869	cellular response to chemokine
0.78	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity

0.77	GO:0071889	14-3-3 protein binding
0.62	GO:0042802	identical protein binding
0.39	GO:0008199	ferric iron binding

0.74	GO:0032420	stereocilium
0.74	GO:0030175	filopodium
0.61	GO:0005856	cytoskeleton
0.60	GO:0032589	neuron projection membrane
0.57	GO:0016324	apical plasma membrane
0.45	GO:0005737	cytoplasm

sp|Q9Y4G2|PKHM1_HUMAN
Pleckstrin homology domain-containing family M member 1
Search

PLEKHM1

0.95	Pleckstrin like proteiny domain-containing family M member 1

0.71	GO:1900029	positive regulation of ruffle assembly
0.70	GO:0046852	positive regulation of bone remodeling
0.69	GO:0045124	regulation of bone resorption
0.68	GO:0032418	lysosome localization
0.65	GO:0032846	positive regulation of homeostatic process
0.62	GO:0035556	intracellular signal transduction
0.44	GO:0006914	autophagy
0.40	GO:0015031	protein transport

0.51	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.58	GO:0005730	nucleolus
0.45	GO:0005765	lysosomal membrane
0.44	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y4G6|TLN2_HUMAN
Talin-2
Search

TLN2

0.95

Talin-2

0.83	GO:0007016	cytoskeletal anchoring at plasma membrane
0.72	GO:0007155	cell adhesion
0.35	GO:0007043	cell-cell junction assembly

0.78	GO:0051015	actin filament binding
0.75	GO:0005200	structural constituent of cytoskeleton

0.81	GO:0001726	ruffle
0.80	GO:0005925	focal adhesion
0.67	GO:0005856	cytoskeleton
0.37	GO:0005916	fascia adherens
0.37	GO:0045202	synapse
0.33	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm

sp|Q9Y4G8|RPGF2_HUMAN
Rap guanine nucleotide exchange factor 2
Search

RAPGEF2

0.89	Rap guanine nucleotide exchange factor 2

0.76	GO:0042127	regulation of cell proliferation
0.76	GO:0043547	positive regulation of GTPase activity
0.71	GO:0007264	small GTPase mediated signal transduction
0.55	GO:2000670	positive regulation of dendritic cell apoptotic process
0.55	GO:2000481	positive regulation of cAMP-dependent protein kinase activity
0.55	GO:0071321	cellular response to cGMP
0.54	GO:0090557	establishment of endothelial intestinal barrier
0.54	GO:0030033	microvillus assembly
0.54	GO:0050774	negative regulation of dendrite morphogenesis
0.54	GO:0043950	positive regulation of cAMP-mediated signaling

0.86	GO:0017034	Rap guanyl-nucleotide exchange factor activity
0.76	GO:0005096	GTPase activator activity
0.56	GO:0031697	beta-1 adrenergic receptor binding
0.53	GO:0070300	phosphatidic acid binding
0.53	GO:0050699	WW domain binding
0.52	GO:0030165	PDZ domain binding
0.52	GO:0030552	cAMP binding
0.37	GO:0030553	cGMP binding
0.36	GO:0019901	protein kinase binding
0.30	GO:0019992	diacylglycerol binding

0.50	GO:0016324	apical plasma membrane
0.50	GO:0030139	endocytic vesicle
0.50	GO:0005923	bicellular tight junction
0.50	GO:0005770	late endosome
0.49	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005829	cytosol
0.39	GO:0043025	neuronal cell body
0.38	GO:0043005	neuron projection
0.38	GO:0045202	synapse
0.35	GO:0043234	protein complex

sp|Q9Y4H2|IRS2_HUMAN
Insulin receptor substrate 2
Search

IRS2

0.79	Insulin receptor substrate 2

0.84	GO:0032000	positive regulation of fatty acid beta-oxidation
0.84	GO:0045725	positive regulation of glycogen biosynthetic process
0.83	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.83	GO:0008286	insulin receptor signaling pathway
0.81	GO:0046326	positive regulation of glucose import
0.78	GO:0002903	negative regulation of B cell apoptotic process
0.76	GO:0002053	positive regulation of mesenchymal cell proliferation
0.75	GO:0050796	regulation of insulin secretion
0.75	GO:0030890	positive regulation of B cell proliferation
0.74	GO:0090277	positive regulation of peptide hormone secretion

0.84	GO:0043548	phosphatidylinositol 3-kinase binding
0.78	GO:0005158	insulin receptor binding
0.68	GO:0019901	protein kinase binding
0.59	GO:0071889	14-3-3 protein binding
0.57	GO:0004871	signal transducer activity
0.56	GO:0019903	protein phosphatase binding
0.53	GO:0019904	protein domain specific binding
0.50	GO:0005159	insulin-like growth factor receptor binding
0.49	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.48	GO:0001784	phosphotyrosine residue binding

0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.53	GO:0043234	protein complex
0.46	GO:0045121	membrane raft
0.41	GO:0005634	nucleus
0.34	GO:1902911	protein kinase complex
0.34	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.49	EC:2.7.1.153	GO:0046934
0.49	KEGG:R04545	GO:0046934

sp|Q9Y4H4|GPSM3_HUMAN
G-protein-signaling modulator 3
Search

GPSM3

0.97	Activator of G-protein signaling 4

0.70	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.68	GO:0050790	regulation of catalytic activity
0.67	GO:0002690	positive regulation of leukocyte chemotaxis
0.43	GO:0007219	Notch signaling pathway
0.40	GO:0030154	cell differentiation
0.40	GO:0007275	multicellular organism development
0.37	GO:0050793	regulation of developmental process
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.76	GO:0030695	GTPase regulator activity
0.40	GO:0005509	calcium ion binding
0.39	GO:0004872	receptor activity
0.36	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.47	GO:0005886	plasma membrane
0.36	GO:0009986	cell surface
0.35	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9Y4I1|MYO5A_HUMAN
Unconventional myosin-Va
Search

MYO5A

0.85	Unconventional myosin-Va

0.74	GO:0007018	microtubule-based movement
0.52	GO:0099089	establishment of endoplasmic reticulum localization to postsynapse
0.52	GO:0032252	secretory granule localization
0.52	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.51	GO:0031987	locomotion involved in locomotory behavior
0.51	GO:0030050	vesicle transport along actin filament
0.50	GO:0030318	melanocyte differentiation
0.50	GO:0030073	insulin secretion
0.50	GO:0032400	melanosome localization
0.50	GO:0042759	long-chain fatty acid biosynthetic process

0.75	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0000146	microfilament motor activity
0.49	GO:0097718	disordered domain specific binding
0.48	GO:0017137	Rab GTPase binding

0.77	GO:0016459	myosin complex
0.51	GO:0032593	insulin-responsive compartment
0.50	GO:0032433	filopodium tip
0.50	GO:0042470	melanosome
0.50	GO:0035371	microtubule plus-end
0.49	GO:0042641	actomyosin
0.49	GO:0001750	photoreceptor outer segment
0.48	GO:0001726	ruffle
0.48	GO:0055037	recycling endosome
0.48	GO:0005884	actin filament

sp|Q9Y4I5|MTL5_HUMAN
Tesmin
Search

TESMIN

0.97	Testis expressed metallothionein like protein

0.50	GO:0007283	spermatogenesis
0.47	GO:0030154	cell differentiation
0.46	GO:0007275	multicellular organism development
0.43	GO:0010038	response to metal ion
0.42	GO:0006875	cellular metal ion homeostasis
0.41	GO:0007049	cell cycle
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression

0.40	GO:0046872	metal ion binding
0.37	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016746

sp|Q9Y4J8|DTNA_HUMAN
Dystrobrevin alpha
Search

DTNA

0.86	Dystrobrevin alpha

0.36	GO:0007274	neuromuscular synaptic transmission
0.36	GO:0006941	striated muscle contraction
0.33	GO:0007165	signal transduction

0.62	GO:0008270	zinc ion binding
0.37	GO:0030165	PDZ domain binding

0.42	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.39	GO:0042383	sarcolemma
0.37	GO:0045202	synapse
0.37	GO:0030054	cell junction
0.37	GO:0030424	axon
0.36	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

sp|Q9Y4K0|LOXL2_HUMAN
Lysyl oxidase homolog 2
Search

LOXL2

0.87	Lysyl oxidase like protein 2

0.71	GO:0006898	receptor-mediated endocytosis
0.66	GO:0018057	peptidyl-lysine oxidation
0.64	GO:1902455	negative regulation of stem cell population maintenance
0.63	GO:0032332	positive regulation of chondrocyte differentiation
0.63	GO:0001935	endothelial cell proliferation
0.62	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.61	GO:0030199	collagen fibril organization
0.61	GO:0002040	sprouting angiogenesis
0.61	GO:0001837	epithelial to mesenchymal transition
0.61	GO:0070828	heterochromatin organization

0.80	GO:0005044	scavenger receptor activity
0.75	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.71	GO:0005507	copper ion binding
0.62	GO:0070492	oligosaccharide binding
0.46	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0001968	fibronectin binding
0.34	GO:0009055	electron transfer activity

0.54	GO:0005615	extracellular space
0.53	GO:0000785	chromatin
0.52	GO:0005783	endoplasmic reticulum
0.50	GO:0005654	nucleoplasm
0.45	GO:0005604	basement membrane
0.34	GO:0043235	receptor complex
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:1.4.3

GO:0016641

sp|Q9Y4K1|AIM1_HUMAN
Absent in melanoma 1 protein
Search

CRYBG1

0.95	Crystallin beta-gamma domain containing 1

0.69

GO:0030246

carbohydrate binding

sp|Q9Y4K3|TRAF6_HUMAN
TNF receptor-associated factor 6
Search

TRAF6

0.77	TNF receptor-associated factor 6

0.77	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.72	GO:0016567	protein ubiquitination
0.70	GO:0042981	regulation of apoptotic process
0.64	GO:0002726	positive regulation of T cell cytokine production
0.64	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.63	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.63	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.63	GO:0045672	positive regulation of osteoclast differentiation
0.63	GO:2000679	positive regulation of transcription regulatory region DNA binding
0.63	GO:0032743	positive regulation of interleukin-2 production

0.83	GO:0005164	tumor necrosis factor receptor binding
0.73	GO:0004842	ubiquitin-protein transferase activity
0.64	GO:0043422	protein kinase B binding
0.64	GO:0031996	thioesterase binding
0.64	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.62	GO:0031624	ubiquitin conjugating enzyme binding
0.61	GO:0047485	protein N-terminus binding
0.61	GO:0042826	histone deacetylase binding
0.60	GO:0008270	zinc ion binding
0.58	GO:0031625	ubiquitin protein ligase binding

0.63	GO:0035631	CD40 receptor complex
0.59	GO:0005811	lipid droplet
0.58	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0009898	cytoplasmic side of plasma membrane
0.51	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.47	GO:0043234	protein complex
0.43	GO:0005938	cell cortex
0.36	GO:0010008	endosome membrane

0.73

GO:0004842

sp|Q9Y4K4|M4K5_HUMAN
Mitogen-activated protein kinase kinase kinase kinase 5
Search

MAP4K5

0.83	Mitogen-activated protein kinase kinase kinase kinase

0.84	GO:0000185	activation of MAPKKK activity
0.78	GO:0000165	MAPK cascade
0.47	GO:0031098	stress-activated protein kinase signaling cascade
0.44	GO:0007346	regulation of mitotic cell cycle
0.44	GO:0042981	regulation of apoptotic process
0.36	GO:0043507	positive regulation of JUN kinase activity
0.36	GO:0000187	activation of MAPK activity
0.32	GO:0055114	oxidation-reduction process

0.85	GO:0008349	MAP kinase kinase kinase kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.44	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.85

GO:0008349

sp|Q9Y4L1|HYOU1_HUMAN
Hypoxia up-regulated protein 1
Search

HYOU1

0.91	Hypoxia up-regulated protein 1

0.64	GO:1903382	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway
0.64	GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.61	GO:0002931	response to ischemia
0.60	GO:0071456	cellular response to hypoxia
0.57	GO:0034976	response to endoplasmic reticulum stress
0.56	GO:0006888	ER to Golgi vesicle-mediated transport
0.36	GO:0034620	cellular response to unfolded protein
0.35	GO:0006898	receptor-mediated endocytosis
0.33	GO:0007165	signal transduction
0.32	GO:0055085	transmembrane transport

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0051087	chaperone binding

0.62	GO:0034663	endoplasmic reticulum chaperone complex
0.43	GO:0005788	endoplasmic reticulum lumen
0.38	GO:0005790	smooth endoplasmic reticulum
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.37	GO:0071682	endocytic vesicle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y4L5|RN115_HUMAN
E3 ubiquitin-protein ligase RNF115
Search

RNF115

0.52	Breast cancer associated protein 2

0.64	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.64	GO:0070534	protein K63-linked ubiquitination
0.64	GO:0070936	protein K48-linked ubiquitination
0.62	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.62	GO:0051865	protein autoubiquitination
0.51	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.49	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.39	GO:0071218	cellular response to misfolded protein
0.39	GO:0006513	protein monoubiquitination
0.39	GO:0042147	retrograde transport, endosome to Golgi

0.59	GO:0061630	ubiquitin protein ligase activity
0.54	GO:0016874	ligase activity
0.40	GO:0005154	epidermal growth factor receptor binding
0.34	GO:0046872	metal ion binding

0.54	GO:0005829	cytosol
0.37	GO:0005654	nucleoplasm
0.34	GO:0005779	integral component of peroxisomal membrane

0.54

GO:0016874

sp|Q9Y4M8|CH071_HUMAN
Putative uncharacterized protein encoded by LINC00588
Search

sp|Q9Y4P1|ATG4B_HUMAN
Cysteine protease ATG4B
Search

ATG4B

0.60	Cysteine protease

0.77	GO:0006914	autophagy
0.65	GO:0015031	protein transport
0.62	GO:0051697	protein delipidation
0.61	GO:0006508	proteolysis
0.56	GO:0007033	vacuole organization
0.51	GO:0070925	organelle assembly
0.48	GO:0006501	C-terminal protein lipidation
0.47	GO:0061726	mitochondrion disassembly
0.43	GO:0090150	establishment of protein localization to membrane
0.42	GO:0046907	intracellular transport

0.75	GO:0004197	cysteine-type endopeptidase activity
0.34	GO:0005515	protein binding

0.49

GO:0005737

cytoplasm

0.75

GO:0004197

sp|Q9Y4P3|TBL2_HUMAN
Transducin beta-like protein 2
Search

TBL2

0.96	Transducin beta like 2

0.79	GO:0042149	cellular response to glucose starvation
0.79	GO:0071456	cellular response to hypoxia
0.77	GO:0030968	endoplasmic reticulum unfolded protein response
0.35	GO:0000398	mRNA splicing, via spliceosome

0.78	GO:0051219	phosphoprotein binding
0.76	GO:0031369	translation initiation factor binding
0.73	GO:0019901	protein kinase binding
0.37	GO:0003723	RNA binding

0.66	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.30	GO:0016021	integral component of membrane

sp|Q9Y4P8|WIPI2_HUMAN
WD repeat domain phosphoinositide-interacting protein 2
Search

WIPI2

0.94	WD repeat domain phosphoinositide-interacting protein 2

0.80	GO:0000045	autophagosome assembly
0.55	GO:0098792	xenophagy
0.53	GO:0006501	C-terminal protein lipidation
0.46	GO:0034613	cellular protein localization
0.45	GO:0044804	autophagy of nucleus
0.45	GO:0000422	autophagy of mitochondrion
0.37	GO:0097352	autophagosome maturation

0.82	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.80	GO:0032266	phosphatidylinositol-3-phosphate binding
0.38	GO:0010314	phosphatidylinositol-5-phosphate binding
0.34	GO:0005515	protein binding

0.79	GO:0000407	phagophore assembly site
0.52	GO:0005776	autophagosome
0.48	GO:0098805	whole membrane
0.47	GO:0005829	cytosol
0.46	GO:0005654	nucleoplasm
0.42	GO:0019898	extrinsic component of membrane
0.42	GO:0043234	protein complex

sp|Q9Y4P9|SPEF1_HUMAN
Sperm flagellar protein 1
Search

SPEF1

0.96	Sperm flagellar protein 1

0.68	GO:0007026	negative regulation of microtubule depolymerization
0.42	GO:0016477	cell migration
0.36	GO:0007229	integrin-mediated signaling pathway
0.34	GO:0006508	proteolysis

0.59	GO:0008017	microtubule binding
0.35	GO:0004222	metalloendopeptidase activity
0.33	GO:0046872	metal ion binding

0.78	GO:0031514	motile cilium
0.43	GO:0005930	axoneme
0.30	GO:0016020	membrane

0.35

GO:0004222

sp|Q9Y4R7|TTLL3_HUMAN
Tubulin monoglycylase TTLL3
Search

TTLL3

0.81	LOW QUALITY PROTEIN: tubulin monoglycylase TTLL3

0.77	GO:0018094	protein polyglycylation
0.45	GO:0035082	axoneme assembly
0.40	GO:0030041	actin filament polymerization
0.39	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.38	GO:0003341	cilium movement

0.77	GO:0070735	protein-glycine ligase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005930	axoneme
0.42	GO:0005874	microtubule
0.39	GO:0005829	cytosol
0.39	GO:0005885	Arp2/3 protein complex
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:6.3.2

GO:0070735

sp|Q9Y4R8|TELO2_HUMAN
Telomere length regulation protein TEL2 homolog
Search

TELO2

0.95	Telomere maintenance 2

0.86	GO:1904515	positive regulation of TORC2 signaling
0.82	GO:1904263	positive regulation of TORC1 signaling
0.78	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.78	GO:0050821	protein stabilization

0.85	GO:0051879	Hsp90 protein binding
0.76	GO:0032947	protein complex scaffold activity
0.76	GO:0019901	protein kinase binding
0.73	GO:0032403	protein complex binding

0.81	GO:0031931	TORC1 complex
0.80	GO:0031932	TORC2 complex
0.79	GO:0034399	nuclear periphery
0.76	GO:0016604	nuclear body
0.67	GO:0005829	cytosol
0.47	GO:0000781	chromosome, telomeric region
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y4U1|MMAC_HUMAN
Methylmalonic aciduria and homocystinuria type C protein
Search

MMACHC

0.97	Methylmalonic aciduria and homocystinuria type C

0.81	GO:0070988	demethylation
0.75	GO:0006749	glutathione metabolic process
0.72	GO:0009236	cobalamin biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.38	GO:0048703	embryonic viscerocranium morphogenesis

0.88	GO:0033787	cyanocobalamin reductase (cyanide-eliminating) activity
0.85	GO:0043295	glutathione binding
0.84	GO:0032451	demethylase activity
0.74	GO:0042803	protein homodimerization activity
0.73	GO:0071949	FAD binding
0.45	GO:0031419	cobalamin binding

0.60	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol

0.88	EC:1.16.1.6	GO:0033787
0.88	KEGG:R02999	GO:0033787

sp|Q9Y4W2|LAS1L_HUMAN
Ribosomal biogenesis protein LAS1L
Search

LAS1L

0.91	LAS1 like, ribosome biogenesis factor

0.60	GO:0000478	endonucleolytic cleavage involved in rRNA processing
0.60	GO:0000470	maturation of LSU-rRNA
0.59	GO:0000460	maturation of 5.8S rRNA
0.54	GO:0006325	chromatin organization
0.34	GO:0006468	protein phosphorylation
0.34	GO:0071897	DNA biosynthetic process
0.34	GO:0097271	protein localization to bud neck
0.34	GO:0000917	division septum assembly
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0055085	transmembrane transport

0.40	GO:0003723	RNA binding
0.34	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008144	drug binding
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0140097	catalytic activity, acting on DNA
0.33	GO:0003677	DNA binding

0.78	GO:0071339	MLL1 complex
0.59	GO:0030687	preribosome, large subunit precursor
0.43	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm
0.36	GO:0005935	cellular bud neck
0.32	GO:0016586	RSC-type complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7

GO:0016772

sp|Q9Y4W6|AFG32_HUMAN
AFG3-like protein 2
Search

AFG3L2

0.95	AFG3 like matrix AAA peptidase subunit 2

0.61	GO:0006508	proteolysis
0.55	GO:0060013	righting reflex
0.54	GO:0036444	mitochondrial calcium uptake
0.53	GO:0008053	mitochondrial fusion
0.53	GO:0042407	cristae formation
0.53	GO:0051560	mitochondrial calcium ion homeostasis
0.52	GO:0021675	nerve development
0.52	GO:0048747	muscle fiber development
0.52	GO:0007528	neuromuscular junction development
0.52	GO:0040014	regulation of multicellular organism growth

0.70	GO:0004222	metalloendopeptidase activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.56

GO:0005745

m-AAA complex

0.70

GO:0004222

sp|Q9Y4X0|AMMR1_HUMAN
AMME syndrome candidate gene 1 protein
Search

AMMECR1

0.96	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

0.37

GO:0005515

protein binding

0.60	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q9Y4X1|UD2A1_HUMAN
UDP-glucuronosyltransferase 2A1
Search

0.53	UDP-glucuronosyltransferase

0.55	GO:0052695	cellular glucuronidation
0.38	GO:0008202	steroid metabolic process
0.37	GO:0007608	sensory perception of smell
0.36	GO:0034754	cellular hormone metabolic process
0.36	GO:0042221	response to chemical
0.35	GO:0018879	biphenyl metabolic process
0.34	GO:0051606	detection of stimulus
0.34	GO:0009617	response to bacterium
0.34	GO:0071495	cellular response to endogenous stimulus
0.33	GO:0051716	cellular response to stimulus

0.79	GO:0015020	glucuronosyltransferase activity
0.40	GO:0001972	retinoic acid binding

0.41	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.36	GO:0031090	organelle membrane
0.35	GO:0044444	cytoplasmic part
0.34	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:2.4.1.17

GO:0015020

sp|Q9Y4X3|CCL27_HUMAN
C-C motif chemokine 27
Search

CCL27

0.97	C-C motif chemokine ligand 27

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.44	GO:0010469	regulation of receptor activity
0.44	GO:0010820	positive regulation of T cell chemotaxis
0.43	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.43	GO:0071677	positive regulation of mononuclear cell migration
0.40	GO:0031640	killing of cells of other organism
0.39	GO:0007267	cell-cell signaling
0.39	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0043207	response to external biotic stimulus

0.84	GO:0008009	chemokine activity
0.79	GO:0031728	CCR3 chemokine receptor binding

0.66	GO:0005576	extracellular region
0.37	GO:0005634	nucleus

sp|Q9Y4X4|KLF12_HUMAN
Krueppel-like factor 12
Search

KLF12

0.97	Kruppel like factor 12

0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.47	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003714	transcription corepressor activity
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y4X5|ARI1_HUMAN
E3 ubiquitin-protein ligase ARIH1
Search

ARIH1

0.58	RING-type E3 ubiquitin transferase

0.72	GO:0016567	protein ubiquitination
0.53	GO:0006511	ubiquitin-dependent protein catabolic process
0.49	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.32	GO:0006355	regulation of transcription, DNA-templated

0.73	GO:0004842	ubiquitin-protein transferase activity
0.61	GO:0031624	ubiquitin conjugating enzyme binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0046872	metal ion binding
0.51	GO:0016874	ligase activity
0.46	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0008233	peptidase activity
0.33	GO:0017171	serine hydrolase activity
0.32	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0097413	Lewy body
0.60	GO:0031462	Cul2-RING ubiquitin ligase complex
0.59	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.57	GO:0019005	SCF ubiquitin ligase complex
0.57	GO:0031463	Cul3-RING ubiquitin ligase complex
0.54	GO:0016604	nuclear body
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.51	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q9Y4Y9|LSM5_HUMAN
U6 snRNA-associated Sm-like protein LSm5
Search

LSM5

0.89	LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated

0.47	GO:0000956	nuclear-transcribed mRNA catabolic process
0.46	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0000413	protein peptidyl-prolyl isomerization

0.41	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.58	GO:0030529	intracellular ribonucleoprotein complex
0.50	GO:1990726	Lsm1-7-Pat1 complex
0.43	GO:0044428	nuclear part
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen

0.33

GO:0003755

sp|Q9Y4Z0|LSM4_HUMAN
U6 snRNA-associated Sm-like protein LSm4
Search

LSM4

0.91	LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated

0.78	GO:0000956	nuclear-transcribed mRNA catabolic process
0.75	GO:0000398	mRNA splicing, via spliceosome
0.47	GO:0033962	cytoplasmic mRNA processing body assembly
0.33	GO:0050794	regulation of cellular process
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.33	GO:0051716	cellular response to stimulus
0.32	GO:0010556	regulation of macromolecule biosynthetic process
0.32	GO:0080090	regulation of primary metabolic process
0.32	GO:0051171	regulation of nitrogen compound metabolic process

0.54	GO:0042731	PH domain binding
0.46	GO:0017070	U6 snRNA binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.57	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005829	cytosol
0.44	GO:0120114	Sm-like protein family complex
0.42	GO:0043234	protein complex
0.41	GO:0019013	viral nucleocapsid
0.41	GO:0044428	nuclear part
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0043005	neuron projection
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y4Z2|NGN3_HUMAN
Neurogenin-3
Search

NEUROG3

0.95	Neurogenin-3

0.71	GO:0022008	neurogenesis
0.69	GO:0031018	endocrine pancreas development
0.60	GO:0060290	transdifferentiation
0.56	GO:0051091	positive regulation of DNA binding transcription factor activity
0.56	GO:0050773	regulation of dendrite development
0.55	GO:0051960	regulation of nervous system development
0.55	GO:0060284	regulation of cell development
0.54	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.54	GO:0030855	epithelial cell differentiation

0.68	GO:0046983	protein dimerization activity
0.57	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0031490	chromatin DNA binding
0.56	GO:0001047	core promoter binding
0.54	GO:0003713	transcription coactivator activity
0.41	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0042802	identical protein binding
0.32	GO:0008270	zinc ion binding

0.46	GO:0005634	nucleus
0.35	GO:0043204	perikaryon
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9Y508|RN114_HUMAN
E3 ubiquitin-protein ligase RNF114
Search

RNF114

0.71	Ring finger protein 114

0.52	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0000209	protein polyubiquitination
0.42	GO:0007283	spermatogenesis
0.40	GO:0030154	cell differentiation
0.40	GO:0007275	multicellular organism development
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.52	GO:0031624	ubiquitin conjugating enzyme binding
0.49	GO:0046872	metal ion binding
0.48	GO:0061630	ubiquitin protein ligase activity
0.40	GO:0016874	ligase activity
0.37	GO:0003676	nucleic acid binding
0.33	GO:0003735	structural constituent of ribosome

0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.38	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.40

GO:0016874

sp|Q9Y512|SAM50_HUMAN
Sorting and assembly machinery component 50 homolog
Search

SAMM50

0.96	Sorting and assembly machinery component 50

0.54	GO:0042407	cristae formation
0.52	GO:0045040	protein import into mitochondrial outer membrane
0.50	GO:0033108	mitochondrial respiratory chain complex assembly
0.35	GO:0001889	liver development
0.32	GO:0006629	lipid metabolic process

0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.66	GO:0019867	outer membrane
0.48	GO:0098805	whole membrane
0.48	GO:0098588	bounding membrane of organelle
0.48	GO:0098798	mitochondrial protein complex
0.47	GO:0044455	mitochondrial membrane part
0.43	GO:0098796	membrane protein complex
0.43	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y519|T184B_HUMAN
Transmembrane protein 184B
Search

TMEM184B

0.96	Transmembrane protein 184B isoform a

0.33

GO:0006468

protein phosphorylation

0.39	GO:0005215	transporter activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

sp|Q9Y520|PRC2C_HUMAN
Protein PRRC2C
Search

PRRC2C

0.96	Proline rich coiled-coil 2C

0.83

GO:0002244

hematopoietic progenitor cell differentiation

0.78

GO:0008022

protein C-terminus binding

0.64

GO:0005829

cytosol

sp|Q9Y530|OARD1_HUMAN
O-acetyl-ADP-ribose deacetylase 1
Search

OARD1

0.97	O-acetyl-ADP-ribose deacetylase 1

0.70	GO:0042278	purine nucleoside metabolic process
0.37	GO:0015074	DNA integration
0.34	GO:0006508	proteolysis

0.74	GO:0019213	deacetylase activity
0.65	GO:0001883	purine nucleoside binding
0.37	GO:0005515	protein binding
0.35	GO:0070001	aspartic-type peptidase activity
0.35	GO:0004175	endopeptidase activity
0.34	GO:0003676	nucleic acid binding

sp|Q9Y534|CSDC2_HUMAN
Cold shock domain-containing protein C2
Search

CSDC2

0.97	Cold shock domain-containing protein C2

0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:0010468	regulation of gene expression
0.44	GO:1903311	regulation of mRNA metabolic process
0.43	GO:0031329	regulation of cellular catabolic process
0.40	GO:0065008	regulation of biological quality
0.36	GO:0006397	mRNA processing

0.51	GO:0003677	DNA binding
0.46	GO:0003730	mRNA 3'-UTR binding
0.37	GO:0008134	transcription factor binding

0.36	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus

sp|Q9Y535|RPC8_HUMAN
DNA-directed RNA polymerase III subunit RPC8
Search

POLR3H

0.91	RNA polymerase III subunit H

0.58	GO:0006351	transcription, DNA-templated
0.46	GO:0061484	hematopoietic stem cell homeostasis
0.37	GO:0045087	innate immune response
0.37	GO:0051607	defense response to virus
0.35	GO:0032481	positive regulation of type I interferon production

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.52	GO:0003677	DNA binding

0.55	GO:0005666	DNA-directed RNA polymerase III complex
0.51	GO:0005813	centrosome
0.33	GO:0005829	cytosol

0.70

GO:0003899

sp|Q9Y536|PAL4A_HUMAN
Peptidyl-prolyl cis-trans isomerase A-like 4A
Search

PPIA

0.46	Peptidyl-prolyl cis-trans isomerase A

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.67	GO:0006457	protein folding
0.48	GO:0045069	regulation of viral genome replication
0.39	GO:0034389	lipid particle organization
0.39	GO:1903902	positive regulation of viral life cycle
0.38	GO:0050714	positive regulation of protein secretion
0.35	GO:0019061	uncoating of virus
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0050900	leukocyte migration

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.40	GO:0016018	cyclosporin A binding
0.35	GO:0046790	virion binding
0.35	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.42	GO:0005829	cytosol
0.41	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005925	focal adhesion
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|Q9Y543|HES2_HUMAN
Transcription factor HES-2
Search

HES2

0.95	Transcription factor HES-2

0.55	GO:0006351	transcription, DNA-templated
0.54	GO:2001141	regulation of RNA biosynthetic process
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.38	GO:0051253	negative regulation of RNA metabolic process
0.38	GO:0010558	negative regulation of macromolecule biosynthetic process
0.38	GO:0031327	negative regulation of cellular biosynthetic process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.68	GO:0046983	protein dimerization activity
0.52	GO:0003677	DNA binding
0.40	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0008134	transcription factor binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003735	structural constituent of ribosome

0.58	GO:0005634	nucleus
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|Q9Y546|LRC42_HUMAN
Leucine-rich repeat-containing protein 42
Search

LRRC42

0.97	Leucine-rich repeat-containing protein 42

0.47

GO:0055114

oxidation-reduction process

0.74

GO:0004800

thyroxine 5'-deiodinase activity

0.74

EC:1.97.1.10

GO:0004800

sp|Q9Y547|IFT25_HUMAN
Intraflagellar transport protein 25 homolog
Search

HSPB11

0.97	Intraflagellar transport protein 25

0.84	GO:0042073	intraciliary transport
0.63	GO:0070986	left/right axis specification
0.60	GO:0030324	lung development
0.59	GO:0007224	smoothened signaling pathway
0.58	GO:0001501	skeletal system development
0.57	GO:0007507	heart development
0.41	GO:0060271	cilium assembly
0.36	GO:0000012	single strand break repair

0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003684	damaged DNA binding

0.84	GO:0030992	intraciliary transport particle B
0.77	GO:0005929	cilium
0.56	GO:0005813	centrosome
0.40	GO:0070062	extracellular exosome
0.36	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9Y548|YIPF1_HUMAN
Protein YIPF1
Search

sp|Q9Y561|LRP12_HUMAN
Low-density lipoprotein receptor-related protein 12
Search

LRP12

0.91	low-density lipoprotein receptor-related protein 3

0.55	GO:0001764	neuron migration
0.52	GO:0031175	neuron projection development
0.48	GO:0006897	endocytosis
0.30	GO:0023052	signaling
0.30	GO:0050789	regulation of biological process
0.30	GO:0051716	cellular response to stimulus
0.30	GO:0007154	cell communication

0.30	GO:0005041	low-density lipoprotein receptor activity
0.30	GO:0005488	binding

0.53	GO:0005905	clathrin-coated pit
0.47	GO:0005887	integral component of plasma membrane

sp|Q9Y566|SHAN1_HUMAN
SH3 and multiple ankyrin repeat domains protein 1
Search

SHANK1

0.87	SH3 and multiple ankyrin repeat domains protein 1

0.86	GO:0050894	determination of affect
0.85	GO:0071625	vocalization behavior
0.85	GO:0046959	habituation
0.85	GO:0060013	righting reflex
0.85	GO:2000463	positive regulation of excitatory postsynaptic potential
0.85	GO:0060997	dendritic spine morphogenesis
0.85	GO:2000311	regulation of AMPA receptor activity
0.84	GO:0032232	negative regulation of actin filament bundle assembly
0.84	GO:0035176	social behavior
0.84	GO:0035418	protein localization to synapse

0.86	GO:0030160	GKAP/Homer scaffold activity
0.85	GO:0035255	ionotropic glutamate receptor binding
0.70	GO:0031877	somatostatin receptor binding
0.66	GO:0071532	ankyrin repeat binding
0.63	GO:0097110	scaffold protein binding
0.61	GO:0008022	protein C-terminus binding
0.58	GO:0017124	SH3 domain binding
0.55	GO:0032403	protein complex binding
0.55	GO:0042802	identical protein binding
0.53	GO:0098919	structural constituent of postsynaptic density

0.84	GO:0060076	excitatory synapse
0.83	GO:0008328	ionotropic glutamate receptor complex
0.82	GO:0044309	neuron spine
0.79	GO:0014069	postsynaptic density
0.78	GO:0030425	dendrite
0.76	GO:0045211	postsynaptic membrane
0.56	GO:0034703	cation channel complex
0.55	GO:0030054	cell junction
0.48	GO:0005829	cytosol
0.41	GO:0005883	neurofilament

sp|Q9Y570|PPME1_HUMAN
Protein phosphatase methylesterase 1
Search

PPME1

0.73	Protein phosphatase methylesterase 1

0.84	GO:0006482	protein demethylation
0.47	GO:0043666	regulation of phosphoprotein phosphatase activity
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.35	GO:0002028	regulation of sodium ion transport
0.35	GO:0035308	negative regulation of protein dephosphorylation
0.35	GO:0010923	negative regulation of phosphatase activity

0.79	GO:0051723	protein methylesterase activity
0.58	GO:0051721	protein phosphatase 2A binding
0.55	GO:0045296	cadherin binding
0.48	GO:0019888	protein phosphatase regulator activity
0.38	GO:0019901	protein kinase binding
0.35	GO:0019212	phosphatase inhibitor activity

0.34

GO:0005654

nucleoplasm

sp|Q9Y572|RIPK3_HUMAN
Receptor-interacting serine/threonine-protein kinase 3
Search

RIPK3

0.93	Receptor-interacting serine-threonine kinase 3

0.73	GO:2000452	regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
0.72	GO:0070235	regulation of activation-induced cell death of T cells
0.71	GO:1990000	amyloid fibril formation
0.71	GO:0060545	positive regulation of necroptotic process
0.70	GO:0070266	necroptotic process
0.70	GO:0001914	regulation of T cell mediated cytotoxicity
0.70	GO:0048535	lymph node development
0.69	GO:0043029	T cell homeostasis
0.69	GO:0046006	regulation of activated T cell proliferation
0.68	GO:0048536	spleen development

0.70	GO:0004704	NF-kappaB-inducing kinase activity
0.58	GO:0032403	protein complex binding
0.57	GO:0042802	identical protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0050700	CARD domain binding
0.39	GO:0004383	guanylate cyclase activity
0.39	GO:0004016	adenylate cyclase activity

0.56	GO:0005829	cytosol
0.38	GO:0005886	plasma membrane
0.37	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.70	EC:2.7.11	GO:0004704
0.33	KEGG:R00162	GO:0004707

sp|Q9Y573|IPP_HUMAN
Actin-binding protein IPP
Search

IPP

0.95	Intracisternal A particle-promoted polypeptide

0.47	GO:0016567	protein ubiquitination
0.36	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.34	GO:0048741	skeletal muscle fiber development
0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0045893	positive regulation of transcription, DNA-templated
0.34	GO:0036268	swimming
0.33	GO:0035914	skeletal muscle cell differentiation
0.33	GO:0045214	sarcomere organization
0.33	GO:0097659	nucleic acid-templated transcription
0.32	GO:0010467	gene expression

0.69	GO:0003779	actin binding
0.47	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0003676	nucleic acid binding
0.36	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0046872	metal ion binding

0.51	GO:0031463	Cul3-RING ubiquitin ligase complex
0.36	GO:0015629	actin cytoskeleton
0.36	GO:0005942	phosphatidylinositol 3-kinase complex
0.33	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.47

GO:0004842

sp|Q9Y574|ASB4_HUMAN
Ankyrin repeat and SOCS box protein 4
Search

ASB4

0.97	Ankyrin repeat and SOCS box-containing protein 4

0.66	GO:0016567	protein ubiquitination
0.65	GO:2001214	positive regulation of vasculogenesis
0.61	GO:0035556	intracellular signal transduction
0.36	GO:0043687	post-translational protein modification
0.32	GO:0006915	apoptotic process
0.32	GO:0006811	ion transport
0.32	GO:0055085	transmembrane transport
0.32	GO:0006468	protein phosphorylation

0.60	GO:0031625	ubiquitin protein ligase binding
0.56	GO:0061630	ubiquitin protein ligase activity
0.32	GO:0005216	ion channel activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.31	GO:0046872	metal ion binding

0.65	GO:0031466	Cul5-RING ubiquitin ligase complex
0.64	GO:0031462	Cul2-RING ubiquitin ligase complex
0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.31	GO:0043233	organelle lumen
0.31	GO:0043232	intracellular non-membrane-bounded organelle
0.31	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0004674

sp|Q9Y575|ASB3_HUMAN
Ankyrin repeat and SOCS box protein 3
Search

ASB3

0.95	Ankyrin repeat and SOCS box-containing 3

0.66	GO:0016567	protein ubiquitination
0.61	GO:0035556	intracellular signal transduction
0.36	GO:0043687	post-translational protein modification
0.32	GO:0016109	tetraterpenoid biosynthetic process
0.32	GO:0016116	carotenoid metabolic process
0.32	GO:0046148	pigment biosynthetic process
0.32	GO:0015074	DNA integration
0.32	GO:0006508	proteolysis
0.32	GO:0006310	DNA recombination
0.31	GO:0006820	anion transport

0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008234	cysteine-type peptidase activity
0.32	GO:0016887	ATPase activity
0.31	GO:0003676	nucleic acid binding

0.48	GO:0000151	ubiquitin ligase complex
0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32	EC:3.4	GO:0008234
0.47	KEGG:R03876	GO:0004842

sp|Q9Y576|ASB1_HUMAN
Ankyrin repeat and SOCS box protein 1
Search

ASB1

0.97	Ankyrin repeat and SOCS box containing 1

0.64	GO:0016567	protein ubiquitination
0.61	GO:0035556	intracellular signal transduction
0.56	GO:0030539	male genitalia development
0.36	GO:0042036	negative regulation of cytokine biosynthetic process
0.35	GO:0043687	post-translational protein modification
0.31	GO:0009116	nucleoside metabolic process

0.52	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0005515	protein binding

0.52	GO:0000151	ubiquitin ligase complex
0.34	GO:0005829	cytosol
0.31	GO:0005634	nucleus

sp|Q9Y577|TRI17_HUMAN
E3 ubiquitin-protein ligase TRIM17
Search

TRIM11

0.85	Tripartite motif containing 4

0.61	GO:0016567	protein ubiquitination
0.60	GO:0006914	autophagy
0.53	GO:0046596	regulation of viral entry into host cell
0.53	GO:1902187	negative regulation of viral release from host cell
0.51	GO:0032880	regulation of protein localization
0.50	GO:0032897	negative regulation of viral transcription
0.50	GO:1903902	positive regulation of viral life cycle
0.49	GO:0045087	innate immune response
0.48	GO:0050768	negative regulation of neurogenesis
0.44	GO:0045892	negative regulation of transcription, DNA-templated

0.62	GO:0008270	zinc ion binding
0.61	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0030674	protein binding, bridging
0.46	GO:0061659	ubiquitin-like protein ligase activity
0.46	GO:0019904	protein domain specific binding
0.45	GO:0008134	transcription factor binding
0.44	GO:0016874	ligase activity
0.36	GO:0045504	dynein heavy chain binding
0.36	GO:0045505	dynein intermediate chain binding
0.32	GO:0004984	olfactory receptor activity

0.45	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.33	GO:0005886	plasma membrane
0.32	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.44	EC:6	GO:0016874
0.61	KEGG:R03876	GO:0004842

sp|Q9Y580|RBM7_HUMAN
RNA-binding protein 7
Search

RBM7

0.95	RNA binding motif protein 7

0.52	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.43	GO:0021693	cerebellar Purkinje cell layer structural organization
0.41	GO:0007409	axonogenesis
0.39	GO:0051321	meiotic cell cycle
0.34	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.33	GO:0034599	cellular response to oxidative stress
0.32	GO:0000398	mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0000175	3'-5'-exoribonuclease activity

0.45	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.13

GO:0000175

sp|Q9Y581|INSL6_HUMAN
Insulin-like peptide INSL6
Search

INSL6

0.97	Insulin-like peptide INSL6

0.76	GO:0010469	regulation of receptor activity
0.46	GO:0030317	flagellated sperm motility
0.45	GO:0008584	male gonad development
0.45	GO:0007286	spermatid development
0.45	GO:0009566	fertilization
0.44	GO:0043066	negative regulation of apoptotic process

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|Q9Y584|TIM22_HUMAN
Mitochondrial import inner membrane translocase subunit Tim22
Search

TIMM22

0.88	Translocase of inner mitochondrial membrane 22

0.59

GO:0045039

protein import into mitochondrial inner membrane

0.50	GO:0030943	mitochondrion targeting sequence binding
0.35	GO:0008320	protein transmembrane transporter activity
0.35	GO:0005515	protein binding

0.59	GO:0042721	mitochondrial inner membrane protein insertion complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y585|OR1A2_HUMAN
Olfactory receptor 1A2
Search

0.37	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0032467	positive regulation of cytokinesis
0.33	GO:0007210	serotonin receptor signaling pathway
0.33	GO:0007283	spermatogenesis

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005549	odorant binding
0.33	GO:0099589	serotonin receptor activity
0.33	GO:0030594	neurotransmitter receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y586|MB212_HUMAN
Protein mab-21-like 2
Search

MAB21L2

0.97	Mab-21 like 2

0.80	GO:0001654	eye development
0.79	GO:0010172	embryonic body morphogenesis
0.71	GO:0008284	positive regulation of cell proliferation
0.56	GO:0048701	embryonic cranial skeleton morphogenesis
0.54	GO:0090596	sensory organ morphogenesis
0.37	GO:0007399	nervous system development

0.36

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

sp|Q9Y587|AP4S1_HUMAN
AP-4 complex subunit sigma-1
Search

AP4S1

0.56	AP complex subunit sigma

0.65	GO:0015031	protein transport
0.41	GO:0046907	intracellular transport
0.41	GO:0034613	cellular protein localization
0.41	GO:0016192	vesicle-mediated transport

0.69

GO:0008565

protein transporter activity

0.54	GO:0030124	AP-4 adaptor complex
0.40	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0012505	endomembrane system
0.35	GO:0031984	organelle subcompartment
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0070013	intracellular organelle lumen

sp|Q9Y592|CEP83_HUMAN
Centrosomal protein of 83 kDa
Search

CEP83

0.82	Centrosomal protein of

0.80	GO:0048278	vesicle docking
0.80	GO:0060271	cilium assembly
0.71	GO:0051660	establishment of centrosome localization
0.43	GO:0071539	protein localization to centrosome

0.35

GO:0005515

protein binding

0.83	GO:0005814	centriole
0.43	GO:0097539	ciliary transition fiber
0.40	GO:0005794	Golgi apparatus
0.36	GO:0005829	cytosol

sp|Q9Y597|KCTD3_HUMAN
BTB/POZ domain-containing protein KCTD3
Search

KCTD3

0.95	Potassium channel tetramerisation domain containing 3

0.78

GO:0051260

protein homooligomerization

0.48	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q9Y5A6|ZSC21_HUMAN
Zinc finger and SCAN domain-containing protein 21
Search

ZSCAN21

0.90	zinc finger protein with KRAB and SCAN domains 5

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0015074	DNA integration
0.34	GO:0042552	myelination
0.32	GO:0048477	oogenesis
0.32	GO:0007283	spermatogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5A7|NUB1_HUMAN
NEDD8 ultimate buster 1
Search

NUB1

0.96	Negative regulator of ubiquitin like proteins 1

0.50	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:0034341	response to interferon-gamma
0.46	GO:0034612	response to tumor necrosis factor
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.45	GO:0016567	protein ubiquitination
0.40	GO:0043687	post-translational protein modification

0.36

GO:0005515

protein binding

0.71	GO:0005730	nucleolus
0.67	GO:0005829	cytosol

sp|Q9Y5A9|YTHD2_HUMAN
YTH domain-containing family protein 2
Search

YTHDF2

0.93	High glucose-regulated protein 8

0.60	GO:1903679	positive regulation of cap-independent translational initiation
0.60	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation
0.59	GO:0061157	mRNA destabilization
0.58	GO:0001556	oocyte maturation
0.47	GO:0098508	endothelial to hematopoietic transition
0.46	GO:1902036	regulation of hematopoietic stem cell differentiation
0.45	GO:0045746	negative regulation of Notch signaling pathway
0.43	GO:0048598	embryonic morphogenesis
0.39	GO:0006402	mRNA catabolic process
0.35	GO:0038003	opioid receptor signaling pathway

0.62	GO:1990247	N6-methyladenosine-containing RNA binding
0.36	GO:0038046	enkephalin receptor activity
0.34	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.34	GO:0043022	ribosome binding
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.54	GO:0000932	P-body
0.51	GO:0005815	microtubule organizing center
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.8.4 EC:1.8.4.11

GO:0008113

sp|Q9Y5B0|CTDP1_HUMAN
RNA polymerase II subunit A C-terminal domain phosphatase
Search

CTDP1

0.89	RNA polymerase II subunit A C-terminal domain phosphatase

0.70	GO:0006470	protein dephosphorylation
0.59	GO:0043923	positive regulation by host of viral transcription
0.59	GO:0010458	exit from mitosis
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development
0.36	GO:0006368	transcription elongation from RNA polymerase II promoter
0.36	GO:0051301	cell division

0.71	GO:0004721	phosphoprotein phosphatase activity
0.62	GO:0001096	TFIIF-class transcription factor binding
0.60	GO:0030957	Tat protein binding

0.60	GO:0005634	nucleus
0.57	GO:0051233	spindle midzone
0.56	GO:0030496	midbody
0.54	GO:0000922	spindle pole
0.54	GO:0005813	centrosome
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0043234	protein complex
0.44	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005737	cytoplasm

0.71

GO:0004721

sp|Q9Y5B6|PAXB1_HUMAN
PAX3- and PAX7-binding protein 1
Search

PAXBP1

0.95	PAX3- and PAX7-binding protein 1

0.60	GO:2000288	positive regulation of myoblast proliferation
0.59	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.57	GO:0031062	positive regulation of histone methylation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0051254	positive regulation of RNA metabolic process
0.52	GO:0010557	positive regulation of macromolecule biosynthetic process
0.52	GO:0031328	positive regulation of cellular biosynthetic process
0.39	GO:0048488	synaptic vesicle endocytosis

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0008134	transcription factor binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.38	GO:0045202	synapse
0.36	GO:0005829	cytosol
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044446	intracellular organelle part

sp|Q9Y5B8|NDK7_HUMAN
Nucleoside diphosphate kinase 7
Search

NME7

0.58	Non-metastatic cells 7, protein expressed in (Nucleoside-diphosphate kinase)

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.56

GO:0005813

centrosome

0.79

EC:2.7.4.6

GO:0004550

sp|Q9Y5B9|SP16H_HUMAN
FACT complex subunit SPT16
Search

SUPT16H

0.84	Chromatin-specific transcription elongation factor large subunit

0.63	GO:0034724	DNA replication-independent nucleosome organization
0.61	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.60	GO:0006368	transcription elongation from RNA polymerase II promoter
0.45	GO:0051301	cell division
0.40	GO:0006281	DNA repair
0.40	GO:0006260	DNA replication
0.39	GO:0031498	chromatin disassembly
0.39	GO:0032986	protein-DNA complex disassembly
0.39	GO:1901796	regulation of signal transduction by p53 class mediator
0.36	GO:0006414	translational elongation

0.62	GO:0031491	nucleosome binding
0.60	GO:0042393	histone binding
0.38	GO:0003723	RNA binding
0.35	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.65	GO:0035101	FACT complex
0.40	GO:0005694	chromosome

sp|Q9Y5C1|ANGL3_HUMAN
Angiopoietin-related protein 3
Search

ANGPTL3

0.97	Angiopoietin like 3

0.82	GO:0051005	negative regulation of lipoprotein lipase activity
0.81	GO:0010519	negative regulation of phospholipase activity
0.79	GO:0055091	phospholipid homeostasis
0.77	GO:0050996	positive regulation of lipid catabolic process
0.77	GO:0070328	triglyceride homeostasis
0.76	GO:0048514	blood vessel morphogenesis
0.75	GO:0060840	artery development
0.75	GO:0042632	cholesterol homeostasis
0.74	GO:0045766	positive regulation of angiogenesis
0.74	GO:0019915	lipid storage

0.77	GO:0004859	phospholipase inhibitor activity
0.75	GO:0005178	integrin binding
0.69	GO:0008083	growth factor activity
0.41	GO:0008201	heparin binding
0.34	GO:0042802	identical protein binding

0.71	GO:0005769	early endosome
0.69	GO:0005615	extracellular space
0.67	GO:0009986	cell surface
0.64	GO:0005794	Golgi apparatus
0.41	GO:0030027	lamellipodium

sp|Q9Y5E1|PCDB9_HUMAN
Protocadherin beta-9
Search

0.95	Protocadherin beta-9

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.51	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.43	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5E2|PCDB7_HUMAN
Protocadherin beta-7
Search

0.94	Protocadherin beta 7

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.49	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.37	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.44	GO:0032391	photoreceptor connecting cilium
0.30	GO:0044425	membrane part

sp|Q9Y5E3|PCDB6_HUMAN
Protocadherin beta-6
Search

0.93	Protocadherin beta-6

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding

0.55	GO:0005886	plasma membrane
0.41	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5E4|PCDB5_HUMAN
Protocadherin beta-5
Search

0.92	Protocadherin beta-5

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.51	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.37	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5E5|PCDB4_HUMAN
Protocadherin beta-4
Search

0.92	Protocadherin beta-4

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.63	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.37	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.44	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5E6|PCDB3_HUMAN
Protocadherin beta-3
Search

0.94	Protocadherin beta-3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.60	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5E7|PCDB2_HUMAN
Protocadherin beta-2
Search

0.94	Protocadherin beta-2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.60	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5E8|PCDBF_HUMAN
Protocadherin beta-15
Search

0.94	Protocadherin beta-3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.60	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.45	GO:0032391	photoreceptor connecting cilium
0.30	GO:0044425	membrane part

sp|Q9Y5E9|PCDBE_HUMAN
Protocadherin beta-14
Search

0.94	Protocadherin beta-2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.65	GO:0007416	synapse assembly
0.60	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5F0|PCDBD_HUMAN
Protocadherin beta-13
Search

0.93	Protocadherin beta-8

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.45	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5F1|PCDBC_HUMAN
Protocadherin beta-12
Search

0.93	Protocadherin beta-2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.49	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.55	GO:0005886	plasma membrane
0.41	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5F2|PCDBB_HUMAN
Protocadherin beta-11
Search

0.94	Protocadherin beta-2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.55	GO:0005886	plasma membrane
0.42	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5F3|PCDB1_HUMAN
Protocadherin beta-1
Search

0.88	Protocadherin beta-1

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.61	GO:0007416	synapse assembly
0.57	GO:0007268	chemical synaptic transmission
0.39	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0009988	cell-cell recognition
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:0009101	glycoprotein biosynthetic process
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.70	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.32	GO:0030246	carbohydrate binding
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.56	GO:0005886	plasma membrane
0.38	GO:0032391	photoreceptor connecting cilium
0.33	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0016757

sp|Q9Y5F6|PCDGM_HUMAN
Protocadherin gamma-C5
Search

0.91	LOW QUALITY PROTEIN: protocadherin gamma-C5

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0007267	cell-cell signaling
0.54	GO:0007399	nervous system development
0.45	GO:0050808	synapse organization
0.40	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0060989	lipid tube assembly involved in organelle fusion
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0007283	spermatogenesis

0.69	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.40	GO:0070062	extracellular exosome
0.37	GO:0005911	cell-cell junction
0.36	GO:0030426	growth cone
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9Y5F7|PCDGL_HUMAN
Protocadherin gamma-C4
Search

0.89	Protocadherin gamma subfamily C, 4

0.76	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0007267	cell-cell signaling
0.55	GO:0007399	nervous system development
0.43	GO:0050808	synapse organization
0.41	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.35	GO:0007283	spermatogenesis
0.33	GO:0060989	lipid tube assembly involved in organelle fusion
0.33	GO:0008333	endosome to lysosome transport

0.68	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.37	GO:0030426	growth cone
0.36	GO:0005911	cell-cell junction
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9Y5F8|PCDGJ_HUMAN
Protocadherin gamma-B7
Search

0.92	Protocadherin gamma B2-alpha C

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0007267	cell-cell signaling
0.55	GO:0007399	nervous system development
0.38	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0050808	synapse organization
0.36	GO:0060989	lipid tube assembly involved in organelle fusion
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.41	GO:0030426	growth cone
0.38	GO:0070062	extracellular exosome
0.34	GO:0005911	cell-cell junction
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9Y5F9|PCDGI_HUMAN
Protocadherin gamma-B6
Search

0.92	Protocadherin gamma B2-alpha C

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.55	GO:0007267	cell-cell signaling
0.55	GO:0007399	nervous system development
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0050808	synapse organization
0.34	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.56	GO:0005886	plasma membrane
0.42	GO:0030426	growth cone
0.38	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q9Y5G0|PCDGH_HUMAN
Protocadherin gamma-B5
Search

0.93	Protocadherin gamma B2-alpha C

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0007267	cell-cell signaling
0.56	GO:0007399	nervous system development
0.39	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0050808	synapse organization
0.36	GO:0060989	lipid tube assembly involved in organelle fusion
0.35	GO:0008333	endosome to lysosome transport
0.32	GO:0007283	spermatogenesis

0.69	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.41	GO:0030426	growth cone
0.39	GO:0070062	extracellular exosome
0.34	GO:0005911	cell-cell junction
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9Y5G1|PCDGF_HUMAN
Protocadherin gamma-B3
Search

0.90	LOW QUALITY PROTEIN: protocadherin gamma-B3

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.55	GO:0007267	cell-cell signaling
0.55	GO:0007399	nervous system development
0.40	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.40	GO:0050808	synapse organization
0.36	GO:0060989	lipid tube assembly involved in organelle fusion
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0007283	spermatogenesis

0.68	GO:0005509	calcium ion binding
0.38	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.40	GO:0030426	growth cone
0.37	GO:0070062	extracellular exosome
0.36	GO:0005911	cell-cell junction
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9Y5G2|PCDGE_HUMAN
Protocadherin gamma-B2
Search

0.92	Protocadherin gamma B2-alpha C

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0007267	cell-cell signaling
0.56	GO:0007399	nervous system development
0.39	GO:0050808	synapse organization
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0060989	lipid tube assembly involved in organelle fusion
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0007283	spermatogenesis

0.69	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.41	GO:0030426	growth cone
0.38	GO:0070062	extracellular exosome
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9Y5G3|PCDGD_HUMAN
Protocadherin gamma-B1
Search

0.93	Protocadherin gamma B2-alpha C

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0007267	cell-cell signaling
0.56	GO:0007399	nervous system development
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0050808	synapse organization
0.34	GO:0007283	spermatogenesis

0.69	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.43	GO:0030426	growth cone
0.38	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q9Y5G4|PCDG9_HUMAN
Protocadherin gamma-A9
Search

0.94	Protocadherin gamma subfamily A 9

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0007267	cell-cell signaling
0.54	GO:0007399	nervous system development
0.41	GO:0060989	lipid tube assembly involved in organelle fusion
0.40	GO:0007283	spermatogenesis
0.39	GO:0008333	endosome to lysosome transport
0.38	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.69	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.35	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.37	GO:0005911	cell-cell junction
0.33	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5G5|PCDG8_HUMAN
Protocadherin gamma-A8
Search

0.93	Protocadherin 4

0.76	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.51	GO:0007267	cell-cell signaling
0.51	GO:0007399	nervous system development
0.38	GO:0007283	spermatogenesis
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.33	GO:0060989	lipid tube assembly involved in organelle fusion
0.33	GO:0008333	endosome to lysosome transport

0.68	GO:0005509	calcium ion binding
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.36	GO:0005911	cell-cell junction
0.31	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5G6|PCDG7_HUMAN
Protocadherin gamma-A7
Search

0.92	Protocadherin gamma subfamily A 9

0.76	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007267	cell-cell signaling
0.52	GO:0007399	nervous system development
0.38	GO:0060989	lipid tube assembly involved in organelle fusion
0.38	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0007283	spermatogenesis
0.36	GO:0008333	endosome to lysosome transport
0.35	GO:0050808	synapse organization

0.68	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.54	GO:0005886	plasma membrane
0.36	GO:0005911	cell-cell junction
0.35	GO:0070062	extracellular exosome
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9Y5G7|PCDG6_HUMAN
Protocadherin gamma-A6
Search

0.93	Protocadherin gamma subfamily A 9

0.75	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007267	cell-cell signaling
0.52	GO:0007399	nervous system development
0.37	GO:0007283	spermatogenesis
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.33	GO:0060989	lipid tube assembly involved in organelle fusion
0.33	GO:0008333	endosome to lysosome transport

0.68	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.54	GO:0005886	plasma membrane
0.36	GO:0005911	cell-cell junction
0.31	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5G8|PCDG5_HUMAN
Protocadherin gamma-A5
Search

0.93	Protocadherin gamma subfamily A 9

0.76	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007267	cell-cell signaling
0.51	GO:0007399	nervous system development
0.38	GO:0060989	lipid tube assembly involved in organelle fusion
0.37	GO:0007283	spermatogenesis
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0008333	endosome to lysosome transport

0.68	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.54	GO:0005886	plasma membrane
0.36	GO:0005911	cell-cell junction
0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5G9|PCDG4_HUMAN
Protocadherin gamma-A4
Search

0.93	Protocadherin gamma subfamily A 9

0.76	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007267	cell-cell signaling
0.52	GO:0007399	nervous system development
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0007283	spermatogenesis
0.33	GO:0060989	lipid tube assembly involved in organelle fusion
0.33	GO:0008333	endosome to lysosome transport

0.68	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.54	GO:0005886	plasma membrane
0.36	GO:0005911	cell-cell junction
0.31	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5H0|PCDG3_HUMAN
Protocadherin gamma-A3
Search

0.92	Protocadherin gamma subfamily A 9

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.38	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0007283	spermatogenesis
0.34	GO:0060989	lipid tube assembly involved in organelle fusion
0.34	GO:0008333	endosome to lysosome transport

0.69	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.38	GO:0005911	cell-cell junction
0.31	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5H1|PCDG2_HUMAN
Protocadherin gamma-A2
Search

0.92	Protocadherin gamma subfamily A 9

0.76	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007267	cell-cell signaling
0.52	GO:0007399	nervous system development
0.39	GO:0060989	lipid tube assembly involved in organelle fusion
0.38	GO:0007283	spermatogenesis
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0008333	endosome to lysosome transport

0.68	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.54	GO:0005886	plasma membrane
0.37	GO:0005911	cell-cell junction
0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5H2|PCDGB_HUMAN
Protocadherin gamma-A11
Search

0.92	Protocadherin gamma subfamily A 9

0.75	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.51	GO:0007267	cell-cell signaling
0.51	GO:0007399	nervous system development
0.40	GO:0060989	lipid tube assembly involved in organelle fusion
0.39	GO:0007283	spermatogenesis
0.38	GO:0008333	endosome to lysosome transport
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.68	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.54	GO:0005886	plasma membrane
0.36	GO:0005911	cell-cell junction
0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5H3|PCDGA_HUMAN
Protocadherin gamma-A10
Search

0.92	Protocadherin gamma subfamily A 9

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007267	cell-cell signaling
0.51	GO:0007399	nervous system development
0.39	GO:0060989	lipid tube assembly involved in organelle fusion
0.38	GO:0007283	spermatogenesis
0.38	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0008333	endosome to lysosome transport

0.69	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.36	GO:0005911	cell-cell junction
0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5H4|PCDG1_HUMAN
Protocadherin gamma-A1
Search

0.92	Protocadherin gamma subfamily C, 4

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007267	cell-cell signaling
0.52	GO:0007399	nervous system development
0.37	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0007283	spermatogenesis
0.34	GO:0060989	lipid tube assembly involved in organelle fusion
0.33	GO:0008333	endosome to lysosome transport

0.69	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.37	GO:0005911	cell-cell junction
0.31	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y5H5|PCDA9_HUMAN
Protocadherin alpha-9
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.37	GO:0005576	extracellular region
0.36	GO:0045202	synapse
0.36	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q9Y5H6|PCDA8_HUMAN
Protocadherin alpha-8
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.38	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.36	GO:0005576	extracellular region
0.36	GO:0045202	synapse
0.36	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q9Y5H7|PCDA5_HUMAN
Protocadherin alpha-5
Search

0.90	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.37	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.36	GO:0045202	synapse
0.30	GO:0044425	membrane part

sp|Q9Y5H8|PCDA3_HUMAN
Protocadherin alpha-3
Search

0.92	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.37	GO:0042476	odontogenesis
0.37	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.41	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0045202	synapse
0.37	GO:0005576	extracellular region
0.36	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q9Y5H9|PCDA2_HUMAN
Protocadherin alpha-2
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.44	GO:0005783	endoplasmic reticulum
0.38	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.36	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5I0|PCDAD_HUMAN
Protocadherin alpha-13
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.38	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.43	GO:0005783	endoplasmic reticulum
0.38	GO:0045202	synapse
0.37	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q9Y5I1|PCDAB_HUMAN
Protocadherin alpha-11
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.38	GO:0009988	cell-cell recognition
0.37	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.43	GO:0005783	endoplasmic reticulum
0.38	GO:0045202	synapse
0.37	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q9Y5I2|PCDAA_HUMAN
Protocadherin alpha-10
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.37	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.37	GO:0005634	nucleus
0.37	GO:0005576	extracellular region
0.36	GO:0045202	synapse
0.30	GO:0044425	membrane part

sp|Q9Y5I3|PCDA1_HUMAN
Protocadherin alpha-1
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.36	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.41	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0045202	synapse
0.37	GO:0005576	extracellular region
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5I4|PCDC2_HUMAN
Protocadherin alpha-C2
Search

PCDHAC2

0.94	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.72	GO:0007399	nervous system development
0.48	GO:0007267	cell-cell signaling
0.34	GO:0009988	cell-cell recognition
0.33	GO:0042476	odontogenesis

0.69	GO:0005509	calcium ion binding
0.34	GO:0042802	identical protein binding

0.55	GO:0005886	plasma membrane
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0045202	synapse
0.33	GO:0005634	nucleus
0.32	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q9Y5I7|CLD16_HUMAN
Claudin-16
Search

CLDN16

0.64

Claudin

0.42	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.37	GO:0007588	excretion
0.36	GO:0006811	ion transport
0.36	GO:0070633	transepithelial transport
0.35	GO:0051928	positive regulation of calcium ion transport
0.35	GO:0006875	cellular metal ion homeostasis
0.33	GO:0055085	transmembrane transport

0.62	GO:0005198	structural molecule activity
0.39	GO:0042802	identical protein binding
0.35	GO:0015095	magnesium ion transmembrane transporter activity

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.36	GO:0098594	mucin granule
0.30	GO:0016021	integral component of membrane

sp|Q9Y5J1|UTP18_HUMAN
U3 small nucleolar RNA-associated protein 18 homolog
Search

UTP18

0.90	UTP18 small subunit processome component

0.64	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.40	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.39	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.39	GO:0000967	rRNA 5'-end processing
0.33	GO:0005975	carbohydrate metabolic process

0.38	GO:0003723	RNA binding
0.34	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.34	GO:0008270	zinc ion binding

0.74	GO:0031965	nuclear membrane
0.71	GO:0005730	nucleolus
0.64	GO:0030686	90S preribosome
0.62	GO:0032040	small-subunit processome
0.49	GO:0043234	protein complex
0.38	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.5

GO:0016810

sp|Q9Y5J3|HEY1_HUMAN
Hairy/enhancer-of-split related with YRPW motif protein 1
Search

HEY1

0.94	Hairy/enhancer-of-split related with YRPW motif protein 1

0.62	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
0.59	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.58	GO:0045746	negative regulation of Notch signaling pathway
0.58	GO:0007219	Notch signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0048514	blood vessel morphogenesis
0.53	GO:0048646	anatomical structure formation involved in morphogenesis
0.44	GO:0060842	arterial endothelial cell differentiation
0.44	GO:0035907	dorsal aorta development
0.43	GO:0061027	umbilical cord development

0.67	GO:0046983	protein dimerization activity
0.61	GO:0035939	microsatellite binding
0.52	GO:0000989	transcription factor activity, transcription factor binding
0.46	GO:0003700	DNA binding transcription factor activity
0.40	GO:0042802	identical protein binding
0.38	GO:0008134	transcription factor binding
0.38	GO:0042826	histone deacetylase binding

0.61	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0017053	transcriptional repressor complex
0.36	GO:0000785	chromatin
0.35	GO:1902494	catalytic complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5J5|PHLA3_HUMAN
Pleckstrin homology-like domain family A member 3
Search

PHLDA3

0.97	Pleckstrin homology like domain family A member 3

0.80	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.79	GO:0051898	negative regulation of protein kinase B signaling
0.72	GO:0043065	positive regulation of apoptotic process
0.55	GO:0045210	FasL biosynthetic process
0.39	GO:0048856	anatomical structure development
0.37	GO:0006937	regulation of muscle contraction
0.36	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0030154	cell differentiation
0.34	GO:0032501	multicellular organismal process

0.81	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.81	GO:0010314	phosphatidylinositol-5-phosphate binding
0.79	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.78	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.78	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.76	GO:0032266	phosphatidylinositol-3-phosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.52	GO:0005886	plasma membrane
0.47	GO:0005730	nucleolus
0.44	GO:0070062	extracellular exosome
0.44	GO:0005861	troponin complex
0.37	GO:0031410	cytoplasmic vesicle
0.34	GO:0005829	cytosol

sp|Q9Y5J6|T10B_HUMAN
Mitochondrial import inner membrane translocase subunit Tim10 B
Search

TIMM10B

0.97	Mitochondrial import inner membrane translocase subunit Tim9 B

0.65	GO:0015031	protein transport
0.37	GO:0007018	microtubule-based movement
0.36	GO:0007160	cell-matrix adhesion
0.36	GO:0072655	establishment of protein localization to mitochondrion
0.36	GO:0006839	mitochondrial transport
0.36	GO:0007005	mitochondrion organization
0.35	GO:0046907	intracellular transport

0.54	GO:0046872	metal ion binding
0.37	GO:0003777	microtubule motor activity
0.34	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005739	mitochondrion
0.50	GO:0031970	organelle envelope lumen
0.45	GO:1990351	transporter complex
0.39	GO:0043234	protein complex
0.39	GO:0019866	organelle inner membrane
0.36	GO:0015630	microtubule cytoskeleton
0.36	GO:0044430	cytoskeletal part
0.35	GO:1902494	catalytic complex
0.30	GO:0044425	membrane part

sp|Q9Y5J7|TIM9_HUMAN
Mitochondrial import inner membrane translocase subunit Tim9
Search

TIMM9

0.87	Translocase of inner mitochondrial membrane 9

0.65	GO:0015031	protein transport
0.57	GO:0090151	establishment of protein localization to mitochondrial membrane
0.57	GO:0007007	inner mitochondrial membrane organization
0.55	GO:1990542	mitochondrial transmembrane transport
0.50	GO:0046907	intracellular transport
0.35	GO:0007605	sensory perception of sound
0.32	GO:0009058	biosynthetic process
0.32	GO:0006518	peptide metabolic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.54	GO:0046872	metal ion binding
0.51	GO:0051087	chaperone binding
0.50	GO:0042803	protein homodimerization activity
0.45	GO:0008565	protein transporter activity
0.34	GO:0030170	pyridoxal phosphate binding
0.33	GO:0003735	structural constituent of ribosome
0.30	GO:0003824	catalytic activity

0.60	GO:0005739	mitochondrion
0.55	GO:0031970	organelle envelope lumen
0.49	GO:1990351	transporter complex
0.46	GO:0019866	organelle inner membrane
0.42	GO:0098796	membrane protein complex
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5J9|TIM8B_HUMAN
Mitochondrial import inner membrane translocase subunit Tim8 B
Search

TIMM8B

0.87	Mitochondrial import inner membrane translocase subunit Tim8 B

0.65	GO:0015031	protein transport
0.43	GO:0030001	metal ion transport
0.41	GO:0098655	cation transmembrane transport
0.36	GO:0010469	regulation of receptor activity
0.36	GO:0072655	establishment of protein localization to mitochondrion
0.36	GO:0006839	mitochondrial transport
0.35	GO:0007005	mitochondrion organization
0.35	GO:0007605	sensory perception of sound
0.35	GO:0046907	intracellular transport
0.33	GO:0007031	peroxisome organization

0.54	GO:0046872	metal ion binding
0.43	GO:0046873	metal ion transmembrane transporter activity
0.37	GO:0005179	hormone activity
0.35	GO:0008566	mitochondrial protein-transporting ATPase activity

0.61	GO:0005739	mitochondrion
0.37	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.37	GO:0005576	extracellular region
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:1990351	transporter complex
0.33	GO:0044438	microbody part
0.33	GO:0005777	peroxisome
0.33	GO:0098805	whole membrane
0.33	GO:0098796	membrane protein complex

0.35

EC:3.6.3.51

GO:0008566

sp|Q9Y5K1|SPO11_HUMAN
Meiotic recombination protein SPO11
Search

SPO11

0.92	Ribonucleic acid export 1

0.83	GO:0000737	DNA catabolic process, endonucleolytic
0.65	GO:0007131	reciprocal meiotic recombination
0.59	GO:0007141	male meiosis I
0.58	GO:0045141	meiotic telomere clustering
0.58	GO:0007130	synaptonemal complex assembly
0.57	GO:0001541	ovarian follicle development
0.56	GO:0034502	protein localization to chromosome
0.56	GO:0007286	spermatid development
0.55	GO:0048477	oogenesis
0.54	GO:0006302	double-strand break repair

0.55	GO:0003677	DNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters
0.46	GO:0061505	DNA topoisomerase II activity
0.44	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0005515	protein binding
0.34	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.33	GO:0046872	metal ion binding

0.68	GO:0005694	chromosome
0.45	GO:0044446	intracellular organelle part
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0005634	nucleus
0.33	GO:0042600	chorion
0.30	GO:0016020	membrane

0.47	EC:3.1.22	GO:0016889
0.33	KEGG:R03532	GO:0004601

sp|Q9Y5K2|KLK4_HUMAN
Kallikrein-4
Search

0.91	Enamel matrix serine proteinase 1

0.61	GO:0006508	proteolysis
0.54	GO:0097186	amelogenesis
0.52	GO:0022617	extracellular matrix disassembly
0.49	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.46	GO:0002803	positive regulation of antibacterial peptide production
0.45	GO:0030163	protein catabolic process
0.44	GO:0070684	seminal clot liquefaction
0.42	GO:0009405	pathogenesis
0.42	GO:0048730	epidermis morphogenesis
0.42	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0090729	toxin activity
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0017080	sodium channel regulator activity
0.32	GO:0016301	kinase activity

0.48	GO:0005576	extracellular region
0.47	GO:0097209	epidermal lamellar body
0.34	GO:0001669	acrosomal vesicle
0.34	GO:0045177	apical part of cell
0.33	GO:0009986	cell surface
0.33	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0035578	azurophil granule lumen
0.33	GO:0019897	extrinsic component of plasma membrane

0.69

GO:0004252

sp|Q9Y5K3|PCY1B_HUMAN
Choline-phosphate cytidylyltransferase B
Search

PCYT1B

0.95	Choline-phosphate cytidylyltransferase B

0.55	GO:0001541	ovarian follicle development
0.52	GO:0007283	spermatogenesis
0.48	GO:0009058	biosynthetic process
0.41	GO:0046470	phosphatidylcholine metabolic process
0.36	GO:1904116	response to vasopressin

0.56

GO:0016779

nucleotidyltransferase activity

0.38	GO:0005783	endoplasmic reticulum
0.38	GO:0042587	glycogen granule
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

0.56

GO:0016779

sp|Q9Y5K5|UCHL5_HUMAN
Ubiquitin carboxyl-terminal hydrolase isozyme L5
Search

UCHL5

0.56	Ubiquitin carboxyl-terminal hydrolase

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.57	GO:0021670	lateral ventricle development
0.57	GO:0048853	forebrain morphogenesis
0.55	GO:0030901	midbrain development
0.53	GO:0061136	regulation of proteasomal protein catabolic process
0.51	GO:0010951	negative regulation of endopeptidase activity
0.45	GO:1904888	cranial skeletal system development
0.36	GO:0006310	DNA recombination
0.36	GO:0006281	DNA repair

0.79	GO:0070628	proteasome binding
0.79	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.52	GO:0004866	endopeptidase inhibitor activity
0.34	GO:0003723	RNA binding

0.75	GO:0031011	Ino80 complex
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.38	GO:1905369	endopeptidase complex
0.36	GO:0043234	protein complex

sp|Q9Y5K6|CD2AP_HUMAN
CD2-associated protein
Search

CD2AP

0.96	CD2-associated protein isoform A

0.85	GO:0032911	negative regulation of transforming growth factor beta1 production
0.81	GO:2000249	regulation of actin cytoskeleton reorganization
0.80	GO:0051058	negative regulation of small GTPase mediated signal transduction
0.78	GO:1900182	positive regulation of protein localization to nucleus
0.71	GO:0007015	actin filament organization
0.47	GO:0039021	pronephric glomerulus development
0.47	GO:0003094	glomerular filtration
0.46	GO:0048259	regulation of receptor-mediated endocytosis
0.44	GO:0016050	vesicle organization
0.44	GO:0016477	cell migration

0.78	GO:0045296	cadherin binding
0.76	GO:0017124	SH3 domain binding
0.48	GO:0005172	vascular endothelial growth factor receptor binding
0.46	GO:0008013	beta-catenin binding
0.46	GO:0008022	protein C-terminus binding
0.43	GO:0032403	protein complex binding
0.39	GO:0005200	structural constituent of cytoskeleton
0.38	GO:0004930	G-protein coupled receptor activity
0.38	GO:0009881	photoreceptor activity
0.34	GO:0003735	structural constituent of ribosome

0.82	GO:0031941	filamentous actin
0.79	GO:0001726	ruffle
0.72	GO:0005911	cell-cell junction
0.53	GO:0005886	plasma membrane
0.47	GO:0005737	cytoplasm
0.42	GO:0070062	extracellular exosome
0.42	GO:0097708	intracellular vesicle
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

sp|Q9Y5K8|VATD_HUMAN
V-type proton ATPase subunit D
Search

ATP6V1D

0.86	V-type proton ATPase subunit D

0.55	GO:0055085	transmembrane transport
0.54	GO:0061512	protein localization to cilium
0.51	GO:0060271	cilium assembly
0.36	GO:0015992	proton transport
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008286	insulin receptor signaling pathway
0.35	GO:0016241	regulation of macroautophagy
0.34	GO:0042998	positive regulation of Golgi to plasma membrane protein transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0005515	protein binding
0.33	GO:0022853	active ion transmembrane transporter activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.50	GO:0005813	centrosome
0.50	GO:0005929	cilium
0.49	GO:0033176	proton-transporting V-type ATPase complex
0.39	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane
0.34	GO:0005802	trans-Golgi network
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y5L0|TNPO3_HUMAN
Transportin-3
Search

TNPO3

0.90	Transportin-3 protein 1

0.58	GO:0035048	splicing factor protein import into nucleus
0.48	GO:0006886	intracellular protein transport
0.45	GO:0030217	T cell differentiation
0.42	GO:0008380	RNA splicing
0.41	GO:0006397	mRNA processing

0.52	GO:0008536	Ran GTPase binding
0.49	GO:0008139	nuclear localization sequence binding
0.49	GO:0042802	identical protein binding
0.44	GO:0008565	protein transporter activity
0.34	GO:0004872	receptor activity

0.60	GO:0005634	nucleus
0.42	GO:0012505	endomembrane system
0.40	GO:0031967	organelle envelope
0.40	GO:0031090	organelle membrane
0.36	GO:0005737	cytoplasm

sp|Q9Y5L2|HLPDA_HUMAN
Hypoxia-inducible lipid droplet-associated protein
Search

HILPDA

0.97	Hypoxia inducible lipid droplet associated

0.86	GO:0010884	positive regulation of lipid storage
0.82	GO:0035425	autocrine signaling
0.81	GO:0001819	positive regulation of cytokine production
0.79	GO:0008284	positive regulation of cell proliferation
0.74	GO:0071456	cellular response to hypoxia
0.46	GO:0034389	lipid particle organization

0.64

GO:0005102

receptor binding

0.72	GO:0005811	lipid droplet
0.71	GO:0030141	secretory granule
0.66	GO:0009986	cell surface
0.65	GO:0005615	extracellular space
0.62	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5L3|ENTP2_HUMAN
Ectonucleoside triphosphate diphosphohydrolase 2
Search

ENTPD2

0.96	Ectonucleoside triphosphate diphosphohydrolase 2

0.58	GO:0009137	purine nucleoside diphosphate catabolic process
0.58	GO:0009191	ribonucleoside diphosphate catabolic process
0.55	GO:0030168	platelet activation
0.48	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0009179	purine ribonucleoside diphosphate metabolic process
0.41	GO:0045471	response to ethanol
0.40	GO:0071405	cellular response to methanol
0.40	GO:0046688	response to copper ion
0.37	GO:0034656	nucleobase-containing small molecule catabolic process
0.36	GO:0035457	cellular response to interferon-alpha

0.54	GO:0017110	nucleoside-diphosphatase activity
0.43	GO:0017111	nucleoside-triphosphatase activity
0.35	GO:1901265	nucleoside phosphate binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding
0.34	GO:0036094	small molecule binding
0.34	GO:0043168	anion binding

0.56	GO:0005605	basal lamina
0.42	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0044297	cell body
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.54

EC:3.6.1.6

GO:0017110

sp|Q9Y5L4|TIM13_HUMAN
Mitochondrial import inner membrane translocase subunit Tim13
Search

TIMM13

0.89	Mitochondrial import inner membrane translocase subunit 13

0.65	GO:0015031	protein transport
0.47	GO:0090151	establishment of protein localization to mitochondrial membrane
0.47	GO:0007007	inner mitochondrial membrane organization
0.46	GO:1990542	mitochondrial transmembrane transport
0.43	GO:0046907	intracellular transport
0.35	GO:0007605	sensory perception of sound

0.54	GO:0046872	metal ion binding
0.44	GO:0008565	protein transporter activity
0.34	GO:0005198	structural molecule activity

0.61	GO:0005739	mitochondrion
0.50	GO:0001650	fibrillar center
0.46	GO:0031970	organelle envelope lumen
0.43	GO:0019866	organelle inner membrane
0.42	GO:1990351	transporter complex
0.35	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5L5|LENEP_HUMAN
Lens epithelial cell protein LEP503
Search

LENEP

0.97	Lens epithelial cell protein LEP503

0.70

GO:0007275

multicellular organism development

0.36

GO:0003677

DNA binding

0.34

GO:0005737

cytoplasm

sp|Q9Y5M1|F215A_HUMAN
Uncharacterized protein FAM215A
Search

sp|Q9Y5M6|TISR_HUMAN
Oculomedin
Search

OCLM

0.97	Oculomedin

0.64

GO:0007601

visual perception

0.30

GO:0016021

integral component of membrane

sp|Q9Y5M8|SRPRB_HUMAN
Signal recognition particle receptor subunit beta
Search

SRPRB

0.87	Signal recognition particle receptor subunit beta

0.36	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0042157	lipoprotein metabolic process
0.33	GO:0006869	lipid transport
0.32	GO:0043086	negative regulation of catalytic activity

0.58	GO:0032550	purine ribonucleoside binding
0.58	GO:0032561	guanyl ribonucleotide binding
0.49	GO:0005047	signal recognition particle binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0008289	lipid binding
0.32	GO:0004857	enzyme inhibitor activity
0.31	GO:0003676	nucleic acid binding

0.53	GO:0005881	cytoplasmic microtubule
0.49	GO:0005785	signal recognition particle receptor complex
0.44	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5N1|HRH3_HUMAN
Histamine H3 receptor
Search

HRH3

0.94	Histamine H3 receptor long form

0.71	GO:0001505	regulation of neurotransmitter levels
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0007194	negative regulation of adenylate cyclase activity
0.50	GO:0014050	negative regulation of glutamate secretion
0.50	GO:0014063	negative regulation of serotonin secretion
0.50	GO:0014061	regulation of norepinephrine secretion
0.46	GO:0050890	cognition
0.38	GO:0014053	negative regulation of gamma-aminobutyric acid secretion
0.37	GO:0042756	drinking behavior
0.37	GO:0042755	eating behavior

0.85	GO:0004969	histamine receptor activity
0.33	GO:0008144	drug binding

0.37	GO:0097458	neuron part
0.36	GO:0043209	myelin sheath
0.36	GO:0005886	plasma membrane
0.36	GO:0044456	synapse part
0.35	GO:0120025	plasma membrane bounded cell projection
0.30	GO:0016021	integral component of membrane

sp|Q9Y5N5|HEMK2_HUMAN
HemK methyltransferase family member 2
Search

N6AMT1

0.54	N-6 adenine-specific DNA methyltransferase 1

0.70	GO:0008213	protein alkylation
0.65	GO:0043414	macromolecule methylation
0.42	GO:0030307	positive regulation of cell growth
0.39	GO:0006417	regulation of translation
0.35	GO:0006415	translational termination
0.34	GO:0006305	DNA alkylation
0.34	GO:0044728	DNA methylation or demethylation

0.71	GO:0008276	protein methyltransferase activity
0.50	GO:0003676	nucleic acid binding
0.46	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.34	GO:0009008	DNA-methyltransferase activity
0.33	GO:0005515	protein binding

0.43	GO:0035657	eRF1 methyltransferase complex
0.37	GO:0005737	cytoplasm
0.37	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.71

GO:0008276

sp|Q9Y5N6|ORC6_HUMAN
Origin recognition complex subunit 6
Search

ORC6

0.95	Origin recognition complex subunit 6

0.66	GO:0006260	DNA replication
0.62	GO:0051782	negative regulation of cell division
0.37	GO:0000082	G1/S transition of mitotic cell cycle

0.54	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.83	GO:0005664	nuclear origin of replication recognition complex
0.63	GO:0001650	fibrillar center
0.35	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9Y5P0|O51B4_HUMAN
Olfactory receptor 51B4
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0015671	oxygen transport

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005344	oxygen carrier activity
0.33	GO:0019825	oxygen binding
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.55	GO:0005886	plasma membrane
0.33	GO:0005833	hemoglobin complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5P1|O51B2_HUMAN
Olfactory receptor 51B2
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5P2|CSAG2_HUMAN
Chondrosarcoma-associated gene 2/3 protein
Search

sp|Q9Y5P3|RAI2_HUMAN
Retinoic acid-induced protein 2
Search

RAI2

0.97	Retinoic acid-induced protein 2

0.71	GO:0090102	cochlea development
0.70	GO:0009790	embryo development
0.67	GO:0050890	cognition
0.67	GO:0007605	sensory perception of sound
0.66	GO:0007626	locomotory behavior
0.66	GO:0090596	sensory organ morphogenesis

0.75	GO:0032184	SUMO polymer binding
0.38	GO:0046872	metal ion binding

0.52

GO:0005634

nucleus

sp|Q9Y5P4|C43BP_HUMAN
Collagen type IV alpha-3-binding protein
Search

COL4A3BP

0.93	Lipid-transfer protein CERTL

0.64	GO:0120012	intermembrane sphingolipid transfer
0.63	GO:0035621	ER to Golgi ceramide transport
0.60	GO:0070584	mitochondrion morphogenesis
0.57	GO:0007029	endoplasmic reticulum organization
0.57	GO:0055088	lipid homeostasis
0.57	GO:0006936	muscle contraction
0.57	GO:0003007	heart morphogenesis
0.57	GO:0006672	ceramide metabolic process
0.56	GO:0034976	response to endoplasmic reticulum stress
0.56	GO:0008283	cell proliferation

0.72	GO:0008289	lipid binding
0.64	GO:0120017	intermembrane ceramide transfer activity
0.52	GO:0033218	amide binding
0.46	GO:0016301	kinase activity
0.34	GO:0043168	anion binding
0.33	GO:0005515	protein binding

0.62	GO:0005581	collagen trimer
0.55	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005794	Golgi apparatus
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.40	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5P6|GMPPB_HUMAN
Mannose-1-phosphate guanyltransferase beta
Search

GMPPB

0.58	GDP-mannose pyrophosphorylase B

0.53	GO:0009298	GDP-mannose biosynthetic process
0.37	GO:0035167	larval lymph gland hemopoiesis
0.34	GO:0048747	muscle fiber development
0.34	GO:0032958	inositol phosphate biosynthetic process
0.34	GO:0006486	protein glycosylation
0.32	GO:0016310	phosphorylation

0.63	GO:0016779	nucleotidyltransferase activity
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.43	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.63

GO:0016779

sp|Q9Y5P8|P2R3B_HUMAN
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
Search

PPP2R3B

0.97	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta

0.36	GO:0043666	regulation of phosphoprotein phosphatase activity
0.36	GO:0045786	negative regulation of cell cycle
0.35	GO:0006470	protein dephosphorylation
0.34	GO:0022402	cell cycle process
0.34	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.34	GO:0008285	negative regulation of cell proliferation

0.67	GO:0005509	calcium ion binding
0.36	GO:0019888	protein phosphatase regulator activity
0.36	GO:0004722	protein serine/threonine phosphatase activity
0.34	GO:0005515	protein binding
0.34	GO:0003682	chromatin binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0000159	protein phosphatase type 2A complex
0.34	GO:0005654	nucleoplasm

sp|Q9Y5Q0|FADS3_HUMAN
Fatty acid desaturase 3
Search

FADS3

0.85	Fatty acid desaturase splice variant

0.63	GO:0006629	lipid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.40	GO:0072330	monocarboxylic acid biosynthetic process
0.33	GO:0017144	drug metabolic process

0.53

GO:0016491

oxidoreductase activity

0.41	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005887	integral component of plasma membrane

0.53

GO:0016491

sp|Q9Y5Q3|MAFB_HUMAN
Transcription factor MafB
Search

MAFB

0.93	Basic domain leucine zipper transcription factor

0.61	GO:0021572	rhombomere 6 development
0.61	GO:0021598	abducens nerve morphogenesis
0.60	GO:0021571	rhombomere 5 development
0.59	GO:0035283	central nervous system segmentation
0.59	GO:0045647	negative regulation of erythrocyte differentiation
0.59	GO:0021603	cranial nerve formation
0.58	GO:0045671	negative regulation of osteoclast differentiation
0.57	GO:0007379	segment specification
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0008134	transcription factor binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q9Y5Q5|CORIN_HUMAN
Atrial natriuretic peptide-converting enzyme
Search

CORIN

0.94	Atrial natriuretic peptide-converting enzyme

0.76	GO:0016486	peptide hormone processing
0.60	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide
0.59	GO:0035813	regulation of renal sodium excretion
0.52	GO:0007565	female pregnancy
0.46	GO:0006898	receptor-mediated endocytosis
0.37	GO:1903779	regulation of cardiac conduction
0.34	GO:0007283	spermatogenesis

0.68	GO:0004252	serine-type endopeptidase activity
0.49	GO:0005044	scavenger receptor activity
0.31	GO:0005509	calcium ion binding

0.54	GO:0016604	nuclear body
0.52	GO:0015629	actin cytoskeleton
0.51	GO:0009986	cell surface
0.43	GO:0005886	plasma membrane
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004252

sp|Q9Y5Q6|INSL5_HUMAN
Insulin-like peptide INSL5
Search

INSL5

0.96	Insulin like 5

0.76	GO:0010469	regulation of receptor activity
0.52	GO:2000253	positive regulation of feeding behavior

0.79	GO:0005179	hormone activity
0.48	GO:0001664	G-protein coupled receptor binding

0.66

GO:0005576

extracellular region

sp|Q9Y5Q8|TF3C5_HUMAN
General transcription factor 3C polypeptide 5
Search

GTF3C5

0.95	General transcription factor IIIC subunit 5

0.83	GO:0035914	skeletal muscle cell differentiation
0.58	GO:0001009	transcription by RNA polymerase III
0.42	GO:0042791	5S class rRNA transcription by RNA polymerase III
0.41	GO:0042797	tRNA transcription by RNA polymerase III
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.64	GO:0001003	RNA polymerase III type 2 promoter sequence-specific DNA binding
0.63	GO:0001002	RNA polymerase III type 1 promoter sequence-specific DNA binding
0.36	GO:0005515	protein binding

0.85	GO:0000127	transcription factor TFIIIC complex
0.69	GO:0005654	nucleoplasm

sp|Q9Y5Q9|TF3C3_HUMAN
General transcription factor 3C polypeptide 3
Search

GTF3C3

0.91	General transcription factor IIIC subunit 3

0.62	GO:0006359	regulation of transcription by RNA polymerase III
0.61	GO:0006383	transcription by RNA polymerase III
0.41	GO:0009303	rRNA transcription
0.41	GO:0009304	tRNA transcription
0.34	GO:0006266	DNA ligation
0.33	GO:0071897	DNA biosynthetic process
0.33	GO:0006310	DNA recombination
0.33	GO:0006281	DNA repair

0.64	GO:0000995	transcription factor activity, core RNA polymerase III binding
0.36	GO:0005515	protein binding
0.35	GO:0003677	DNA binding
0.35	GO:0016788	hydrolase activity, acting on ester bonds
0.34	GO:0003910	DNA ligase (ATP) activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0000127	transcription factor TFIIIC complex
0.77	GO:0031965	nuclear membrane
0.71	GO:0005730	nucleolus
0.38	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.1

GO:0016788

sp|Q9Y5R2|MMP24_HUMAN
Matrix metalloproteinase-24
Search

MMP24

0.75	Matrix metalloproteinase

0.60	GO:0006508	proteolysis
0.57	GO:0044331	cell-cell adhesion mediated by cadherin
0.56	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.55	GO:0097150	neuronal stem cell population maintenance
0.53	GO:0010001	glial cell differentiation
0.51	GO:0035988	chondrocyte proliferation
0.51	GO:0097094	craniofacial suture morphogenesis
0.51	GO:0001958	endochondral ossification
0.51	GO:0030574	collagen catabolic process
0.51	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.52	GO:0045296	cadherin binding
0.47	GO:0070006	metalloaminopeptidase activity
0.35	GO:0008047	enzyme activator activity

0.74	GO:0031012	extracellular matrix
0.63	GO:0005887	integral component of plasma membrane
0.54	GO:0032588	trans-Golgi network membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005796	Golgi lumen
0.34	GO:0009986	cell surface

0.70

GO:0004222

sp|Q9Y5R4|HEMK1_HUMAN
HemK methyltransferase family member 1
Search

HEMK1

0.97	HemK methyltransferase family member 1

0.69	GO:0008213	protein alkylation
0.64	GO:0043414	macromolecule methylation
0.47	GO:0006305	DNA alkylation
0.47	GO:0044728	DNA methylation or demethylation

0.70	GO:0008276	protein methyltransferase activity
0.49	GO:0003676	nucleic acid binding
0.46	GO:0008170	N-methyltransferase activity
0.43	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.34	GO:0005515	protein binding

0.47	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0008276

sp|Q9Y5R5|DMRT2_HUMAN
Doublesex- and mab-3-related transcription factor 2
Search

DMRT2

0.97	Doublesex- and mab-3-related transcription factor 2

0.63	GO:2000287	positive regulation of myotome development
0.61	GO:0014807	regulation of somitogenesis
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0048706	embryonic skeletal system development
0.56	GO:0010468	regulation of gene expression
0.52	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process
0.44	GO:0007368	determination of left/right symmetry

0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0043565	sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0042803	protein homodimerization activity
0.51	GO:0003690	double-stranded DNA binding
0.49	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9Y5R6|DMRT1_HUMAN
Doublesex- and mab-3-related transcription factor 1
Search

DMRT1

0.89	DM domain expressed in testis protein 1

0.63	GO:0002176	male germ cell proliferation
0.61	GO:0060008	Sertoli cell differentiation
0.60	GO:2000020	positive regulation of male gonad development
0.60	GO:1900107	regulation of nodal signaling pathway
0.60	GO:0030238	male sex determination
0.59	GO:0060903	positive regulation of meiosis I
0.59	GO:0008354	germ cell migration
0.59	GO:0045835	negative regulation of meiotic nuclear division
0.58	GO:0045840	positive regulation of mitotic nuclear division
0.57	GO:1903506	regulation of nucleic acid-templated transcription

0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0044212	transcription regulatory region DNA binding
0.53	GO:0003682	chromatin binding
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0003690	double-stranded DNA binding
0.52	GO:0046982	protein heterodimerization activity
0.52	GO:0046872	metal ion binding
0.32	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

sp|Q9Y5R8|TPPC1_HUMAN
Trafficking protein particle complex subunit 1
Search

TRAPPC1

0.92	Trafficking protein particle complex subunit 1

0.69	GO:0016192	vesicle-mediated transport
0.48	GO:0046907	intracellular transport
0.47	GO:0065009	regulation of molecular function
0.35	GO:0002283	neutrophil activation involved in immune response
0.35	GO:0002446	neutrophil mediated immunity
0.35	GO:0050880	regulation of blood vessel size
0.35	GO:0051650	establishment of vesicle localization
0.34	GO:0016050	vesicle organization
0.34	GO:0009966	regulation of signal transduction
0.34	GO:0071822	protein complex subunit organization

0.56	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.35	GO:0005179	hormone activity
0.32	GO:0003747	translation release factor activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0030008	TRAPP complex
0.48	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.46	GO:0044440	endosomal part
0.46	GO:0005794	Golgi apparatus
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0035578	azurophil granule lumen
0.35	GO:0005576	extracellular region
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0005829	cytosol
0.34	GO:0031984	organelle subcompartment

sp|Q9Y5S1|TRPV2_HUMAN
Transient receptor potential cation channel subfamily V member 2
Search

TRPV2

0.94	Transient receptor potential cation channel subfamily V member 2

0.70	GO:0070588	calcium ion transmembrane transport
0.69	GO:0009408	response to heat
0.59	GO:0090280	positive regulation of calcium ion import
0.58	GO:0045773	positive regulation of axon extension
0.47	GO:1901594	response to capsazepine
0.46	GO:0050960	detection of temperature stimulus involved in thermoception
0.45	GO:0050968	detection of chemical stimulus involved in sensory perception of pain
0.45	GO:0002024	diet induced thermogenesis
0.45	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.45	GO:0001660	fever generation

0.70	GO:0005216	ion channel activity
0.57	GO:0015085	calcium ion transmembrane transporter activity
0.43	GO:0051219	phosphoprotein binding
0.41	GO:0022834	ligand-gated channel activity
0.36	GO:0042802	identical protein binding
0.35	GO:0005516	calmodulin binding
0.35	GO:0035091	phosphatidylinositol binding
0.34	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding

0.60	GO:0032584	growth cone membrane
0.59	GO:0044295	axonal growth cone
0.55	GO:0044297	cell body
0.52	GO:0009986	cell surface
0.44	GO:0005887	integral component of plasma membrane
0.42	GO:0005622	intracellular
0.37	GO:0031982	vesicle
0.37	GO:0031252	cell leading edge
0.35	GO:0043197	dendritic spine
0.35	GO:0031253	cell projection membrane

sp|Q9Y5S2|MRCKB_HUMAN
Serine/threonine-protein kinase MRCK beta
Search

CDC42BPB

0.94	CDC42 binding protein kinase beta

0.78	GO:0016477	cell migration
0.73	GO:0030036	actin cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.63	GO:0035556	intracellular signal transduction

0.70	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0032403	protein complex binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0046872	metal ion binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0042802	identical protein binding
0.37	GO:0017048	Rho GTPase binding

0.65

GO:0042641

actomyosin

0.70

GO:0004674

sp|Q9Y5S8|NOX1_HUMAN
NADPH oxidase 1
Search

NOX1

0.94	Predicted NADPH oxidase-1

0.82	GO:0042554	superoxide anion generation
0.59	GO:0045726	positive regulation of integrin biosynthetic process
0.59	GO:1990451	cellular stress response to acidic pH
0.58	GO:0072592	oxygen metabolic process
0.58	GO:0045852	pH elevation
0.57	GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.57	GO:0010575	positive regulation of vascular endothelial growth factor production
0.57	GO:0042743	hydrogen peroxide metabolic process
0.57	GO:0071455	cellular response to hyperoxia
0.55	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin

0.82	GO:0016175	superoxide-generating NADPH oxidase activity
0.56	GO:0048365	Rac GTPase binding
0.47	GO:0046982	protein heterodimerization activity
0.44	GO:0050660	flavin adenine dinucleotide binding
0.43	GO:0020037	heme binding
0.42	GO:0009055	electron transfer activity
0.39	GO:0022832	voltage-gated channel activity
0.39	GO:0022839	ion gated channel activity
0.39	GO:0008381	mechanosensitive ion channel activity
0.37	GO:0015252	proton channel activity

0.65	GO:0043020	NADPH oxidase complex
0.59	GO:0071438	invadopodium membrane
0.54	GO:0031410	cytoplasmic vesicle
0.49	GO:0012505	endomembrane system
0.40	GO:0005739	mitochondrion
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.39	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0030054	cell junction
0.37	GO:0044428	nuclear part

0.82

EC:1.6.3

GO:0016175

sp|Q9Y5S9|RBM8A_HUMAN
RNA-binding protein 8A
Search

RBM8A

0.89	RNA-binding protein 8A-B

0.76	GO:0051028	mRNA transport
0.73	GO:0008380	RNA splicing
0.69	GO:0006397	mRNA processing
0.56	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.55	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.40	GO:0006417	regulation of translation
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing
0.34	GO:0006405	RNA export from nucleus

0.75	GO:0003729	mRNA binding
0.34	GO:0005515	protein binding
0.34	GO:0008488	gamma-glutamyl carboxylase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0016607	nuclear speck
0.56	GO:0035145	exon-exon junction complex
0.51	GO:0071013	catalytic step 2 spliceosome
0.49	GO:0005737	cytoplasm
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.30	GO:0016020	membrane

0.34

EC:4.1.1

GO:0008488

sp|Q9Y5T4|DJC15_HUMAN
DnaJ homolog subfamily C member 15
Search

DNAJC15

0.54	Putative molecular chaperone dnaj superfamily

0.44	GO:1905447	negative regulation of mitochondrial ATP synthesis coupled electron transport
0.43	GO:0048806	genitalia development
0.43	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone
0.41	GO:0007601	visual perception
0.40	GO:0031333	negative regulation of protein complex assembly
0.40	GO:0019216	regulation of lipid metabolic process
0.40	GO:0009267	cellular response to starvation
0.40	GO:0015031	protein transport
0.39	GO:0048793	pronephros development
0.36	GO:0032781	positive regulation of ATPase activity

0.36	GO:0001671	ATPase activator activity
0.36	GO:0005515	protein binding
0.34	GO:0008565	protein transporter activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.38	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5T5|UBP16_HUMAN
Ubiquitin carboxyl-terminal hydrolase 16
Search

USP16

0.92	Ubiquitin carboxyl-terminal hydrolase 16

0.80	GO:0051289	protein homotetramerization
0.80	GO:0016578	histone deubiquitination
0.73	GO:0140014	mitotic nuclear division
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.70	GO:0045893	positive regulation of transcription, DNA-templated
0.69	GO:0051726	regulation of cell cycle
0.64	GO:0051301	cell division
0.64	GO:0035520	monoubiquitinated protein deubiquitination
0.62	GO:0070536	protein K63-linked deubiquitination
0.61	GO:0045901	positive regulation of translational elongation

0.77	GO:0043130	ubiquitin binding
0.76	GO:0042393	histone binding
0.75	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.75	GO:0003713	transcription coactivator activity
0.71	GO:0004197	cysteine-type endopeptidase activity
0.60	GO:0008270	zinc ion binding

0.59	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm

0.71

GO:0004197

sp|Q9Y5U2|TSSC4_HUMAN
Protein TSSC4
Search

TSSC4

0.97	Tumor suppressing subtransferable candidate 4

0.39

GO:0006260

DNA replication

0.53	GO:0005515	protein binding
0.36	GO:0003677	DNA binding

0.43	GO:0005664	nuclear origin of replication recognition complex
0.30	GO:0044425	membrane part

sp|Q9Y5U4|INSI2_HUMAN
Insulin-induced gene 2 protein
Search

INSIG2

0.94	Insulin-induced gene protein (Fragment)

0.83	GO:0008203	cholesterol metabolic process
0.59	GO:0060363	cranial suture morphogenesis
0.58	GO:0042474	middle ear morphogenesis
0.58	GO:0010894	negative regulation of steroid biosynthetic process
0.58	GO:0006991	response to sterol depletion
0.57	GO:0006984	ER-nucleus signaling pathway
0.56	GO:0060021	palate development
0.56	GO:0045717	negative regulation of fatty acid biosynthetic process
0.56	GO:0042472	inner ear morphogenesis
0.55	GO:0006641	triglyceride metabolic process

0.37

GO:0008134

transcription factor binding

0.66	GO:0005789	endoplasmic reticulum membrane
0.45	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5U5|TNR18_HUMAN
Tumor necrosis factor receptor superfamily member 18
Search

TNFRSF18

0.96	Tumor necrosis factor receptor superfamily member 18

0.84	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.77	GO:0043066	negative regulation of apoptotic process
0.53	GO:0045785	positive regulation of cell adhesion
0.52	GO:0032496	response to lipopolysaccharide
0.52	GO:0097190	apoptotic signaling pathway
0.51	GO:0006954	inflammatory response
0.50	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.50	GO:0042127	regulation of cell proliferation
0.49	GO:0002687	positive regulation of leukocyte migration
0.49	GO:0006955	immune response

0.85	GO:0005031	tumor necrosis factor-activated receptor activity
0.37	GO:0005515	protein binding

0.66	GO:0005887	integral component of plasma membrane
0.53	GO:0009897	external side of plasma membrane
0.38	GO:0005576	extracellular region

sp|Q9Y5U8|MPC1_HUMAN
Mitochondrial pyruvate carrier 1
Search

MPC1

0.61	Mitochondrial pyruvate carrier

0.84	GO:0006850	mitochondrial pyruvate transmembrane transport
0.46	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate
0.44	GO:1990830	cellular response to leukemia inhibitory factor
0.33	GO:0016192	vesicle-mediated transport

0.53

GO:0050833

pyruvate transmembrane transporter activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.46	GO:0031301	integral component of organelle membrane
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex

sp|Q9Y5U9|IR3IP_HUMAN
Immediate early response 3-interacting protein 1
Search

IER3IP1

0.91	Immediate early response 3-interacting protein 1

0.46	GO:0006888	ER to Golgi vesicle-mediated transport
0.41	GO:2000269	regulation of fibroblast apoptotic process
0.33	GO:0016311	dephosphorylation
0.33	GO:0051056	regulation of small GTPase mediated signal transduction
0.33	GO:0043547	positive regulation of GTPase activity
0.33	GO:0032502	developmental process

0.36	GO:0019899	enzyme binding
0.33	GO:0016791	phosphatase activity
0.33	GO:0005096	GTPase activator activity

0.47	GO:0030173	integral component of Golgi membrane
0.46	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.44	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005634	nucleus

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q9Y5V0|ZN706_HUMAN
Zinc finger protein 706
Search

ZNF706

0.97	Zinc finger protein 706

0.85	GO:1902455	negative regulation of stem cell population maintenance
0.69	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0006417	regulation of translation

0.39	GO:0019904	protein domain specific binding
0.37	GO:0046872	metal ion binding
0.33	GO:0003676	nucleic acid binding

0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5V3|MAGD1_HUMAN
Melanoma-associated antigen D1
Search

MAGED1

0.97	Melanoma-associated antigen D1

0.83	GO:0032922	circadian regulation of gene expression
0.72	GO:0042981	regulation of apoptotic process
0.61	GO:0050680	negative regulation of epithelial cell proliferation
0.60	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.57	GO:0042752	regulation of circadian rhythm
0.56	GO:0043406	positive regulation of MAP kinase activity
0.54	GO:0043068	positive regulation of programmed cell death
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0045892	negative regulation of transcription, DNA-templated
0.50	GO:0006357	regulation of transcription by RNA polymerase II

0.55	GO:0042802	identical protein binding
0.55	GO:0003713	transcription coactivator activity
0.34	GO:0004705	JUN kinase activity

0.52	GO:0000785	chromatin
0.49	GO:0005634	nucleus
0.47	GO:0043234	protein complex
0.43	GO:0005829	cytosol
0.42	GO:0043233	organelle lumen
0.36	GO:0005886	plasma membrane
0.34	GO:0031091	platelet alpha granule
0.33	GO:0044433	cytoplasmic vesicle part
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004705

sp|Q9Y5W3|KLF2_HUMAN
Krueppel-like factor 2
Search

KLF2

0.83	Kruppel like factor 2

0.62	GO:0071499	cellular response to laminar fluid shear stress
0.60	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.56	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress
0.56	GO:0060509	Type I pneumocyte differentiation
0.55	GO:0043249	erythrocyte maturation
0.53	GO:0035264	multicellular organism growth
0.53	GO:0051247	positive regulation of protein metabolic process
0.50	GO:0001701	in utero embryonic development
0.50	GO:0040029	regulation of gene expression, epigenetic
0.49	GO:0009653	anatomical structure morphogenesis

0.52	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:1990841	promoter-specific chromatin binding
0.42	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.42	GO:0001085	RNA polymerase II transcription factor binding
0.41	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting
0.40	GO:0008013	beta-catenin binding
0.36	GO:0046872	metal ion binding
0.32	GO:0001221	transcription cofactor binding
0.32	GO:0035014	phosphatidylinositol 3-kinase regulator activity

0.53	GO:0000790	nuclear chromatin
0.40	GO:0000791	euchromatin
0.39	GO:0005654	nucleoplasm
0.38	GO:0044798	nuclear transcription factor complex
0.34	GO:0005737	cytoplasm

sp|Q9Y5W5|WIF1_HUMAN
Wnt inhibitory factor 1
Search

WIF1

0.97	Wnt inhibitory factor 1

0.76	GO:0045600	positive regulation of fat cell differentiation
0.47	GO:0007166	cell surface receptor signaling pathway
0.47	GO:0007275	multicellular organism development
0.45	GO:0198738	cell-cell signaling by wnt
0.43	GO:0030178	negative regulation of Wnt signaling pathway
0.42	GO:0030154	cell differentiation
0.37	GO:0060828	regulation of canonical Wnt signaling pathway
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.51	GO:0005509	calcium ion binding
0.42	GO:0017147	Wnt-protein binding
0.36	GO:0060089	molecular transducer activity
0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0005178	integrin binding
0.34	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.34	GO:0001085	RNA polymerase II transcription factor binding
0.33	GO:0030695	GTPase regulator activity
0.32	GO:0005520	insulin-like growth factor binding
0.32	GO:0005540	hyaluronic acid binding

0.42	GO:0005576	extracellular region
0.34	GO:0044214	spanning component of plasma membrane
0.34	GO:0016328	lateral plasma membrane
0.33	GO:0090575	RNA polymerase II transcription factor complex
0.33	GO:0012505	endomembrane system
0.33	GO:0031982	vesicle
0.32	GO:0005737	cytoplasm

0.32

EC:3.1.1.4

GO:0004623

sp|Q9Y5W7|SNX14_HUMAN
Sorting nexin-14
Search

SNX14

0.91	Sorting nexin-14 isoform a

0.55	GO:0097352	autophagosome maturation
0.37	GO:0021680	cerebellar Purkinje cell layer development
0.35	GO:0015031	protein transport

0.84

GO:0080025

phosphatidylinositol-3,5-bisphosphate binding

0.51	GO:0005770	late endosome
0.50	GO:0005764	lysosome
0.38	GO:0030425	dendrite
0.36	GO:0098852	lytic vacuole membrane
0.36	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y5W8|SNX13_HUMAN
Sorting nexin-13
Search

SNX13

0.92	Sorting nexin-13

0.69	GO:0043547	positive regulation of GTPase activity
0.49	GO:0006886	intracellular protein transport
0.44	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.43	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway

0.74

GO:0035091

phosphatidylinositol binding

0.54	GO:0005769	early endosome
0.36	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y5W9|SNX11_HUMAN
Sorting nexin-11
Search

SNX11

0.94	Sorting nexin-11

0.66	GO:0034613	cellular protein localization
0.65	GO:0046907	intracellular transport
0.62	GO:0015031	protein transport
0.58	GO:0016050	vesicle organization
0.46	GO:0030316	osteoclast differentiation
0.46	GO:0006897	endocytosis
0.45	GO:1990830	cellular response to leukemia inhibitory factor
0.44	GO:0060271	cilium assembly
0.43	GO:0010256	endomembrane system organization

0.76	GO:0035091	phosphatidylinositol binding
0.45	GO:0051117	ATPase binding

0.56	GO:0005768	endosome
0.50	GO:0019898	extrinsic component of membrane
0.43	GO:0005813	centrosome
0.42	GO:0044433	cytoplasmic vesicle part
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0098805	whole membrane
0.41	GO:0098588	bounding membrane of organelle
0.39	GO:0005634	nucleus

sp|Q9Y5X0|SNX10_HUMAN
Sorting nexin-10
Search

SNX10

0.97	Sorting nexin 10

0.56	GO:0016050	vesicle organization
0.55	GO:0071539	protein localization to centrosome
0.55	GO:0030316	osteoclast differentiation
0.55	GO:0061512	protein localization to cilium
0.54	GO:1990830	cellular response to leukemia inhibitory factor
0.52	GO:0060271	cilium assembly
0.51	GO:0010256	endomembrane system organization
0.49	GO:0006886	intracellular protein transport
0.44	GO:0006897	endocytosis
0.34	GO:0070986	left/right axis specification

0.75	GO:0035091	phosphatidylinositol binding
0.55	GO:0051117	ATPase binding

0.56	GO:0031313	extrinsic component of endosome membrane
0.51	GO:0005813	centrosome
0.48	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus

sp|Q9Y5X1|SNX9_HUMAN
Sorting nexin-9
Search

SNX9

0.77	Sorting nexin

0.81	GO:0000281	mitotic cytokinesis
0.71	GO:0006897	endocytosis
0.69	GO:0006886	intracellular protein transport
0.57	GO:0036089	cleavage furrow formation
0.57	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.57	GO:0060988	lipid tube assembly
0.56	GO:0032461	positive regulation of protein oligomerization
0.56	GO:0097320	plasma membrane tubulation
0.52	GO:0045860	positive regulation of protein kinase activity
0.51	GO:0016197	endosomal transport

0.76	GO:0035091	phosphatidylinositol binding
0.56	GO:0071933	Arp2/3 complex binding
0.53	GO:0045296	cadherin binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0042803	protein homodimerization activity

0.68	GO:0030659	cytoplasmic vesicle membrane
0.52	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.52	GO:0005802	trans-Golgi network
0.52	GO:0030136	clathrin-coated vesicle
0.47	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.37	GO:0001726	ruffle

sp|Q9Y5X2|SNX8_HUMAN
Sorting nexin-8
Search

SNX8

0.97	Sorting nexin-8

0.80	GO:0042147	retrograde transport, endosome to Golgi
0.50	GO:0048193	Golgi vesicle transport
0.48	GO:0006886	intracellular protein transport
0.46	GO:0016050	vesicle organization
0.43	GO:0006897	endocytosis

0.75	GO:0035091	phosphatidylinositol binding
0.50	GO:0042802	identical protein binding

0.67	GO:0005829	cytosol
0.55	GO:0031901	early endosome membrane
0.53	GO:0030904	retromer complex
0.45	GO:0019898	extrinsic component of membrane
0.42	GO:0043231	intracellular membrane-bounded organelle

sp|Q9Y5X3|SNX5_HUMAN
Sorting nexin-5
Search

SNX5

0.78	Sorting nexin

0.85	GO:0006907	pinocytosis
0.68	GO:0006886	intracellular protein transport
0.53	GO:0042147	retrograde transport, endosome to Golgi
0.46	GO:0016050	vesicle organization
0.44	GO:0060041	retina development in camera-type eye
0.44	GO:0042063	gliogenesis
0.44	GO:0007219	Notch signaling pathway
0.43	GO:0048514	blood vessel morphogenesis
0.43	GO:0030097	hemopoiesis
0.35	GO:0016241	regulation of macroautophagy

0.75	GO:0035091	phosphatidylinositol binding
0.57	GO:0034452	dynactin binding
0.53	GO:0045296	cadherin binding
0.34	GO:0046982	protein heterodimerization activity

0.59	GO:0070685	macropinocytic cup
0.58	GO:0097422	tubular endosome
0.58	GO:0031313	extrinsic component of endosome membrane
0.56	GO:0005769	early endosome
0.53	GO:0030904	retromer complex
0.53	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.47	GO:0005829	cytosol
0.40	GO:0001891	phagocytic cup
0.39	GO:0001726	ruffle
0.38	GO:0030659	cytoplasmic vesicle membrane

sp|Q9Y5X4|NR2E3_HUMAN
Photoreceptor-specific nuclear receptor
Search

NR2E3

0.94	Photoreceptor-specific nuclear receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0045872	positive regulation of rhodopsin gene expression
0.58	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0042462	eye photoreceptor cell development
0.55	GO:0060041	retina development in camera-type eye
0.53	GO:0008285	negative regulation of cell proliferation
0.51	GO:1902680	positive regulation of RNA biosynthetic process

0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0008233	peptidase activity

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.33

GO:0008233

sp|Q9Y5X5|NPFF2_HUMAN
Neuropeptide FF receptor 2
Search

NPFFR2

0.95	Neuropeptide FF receptor

0.81	GO:2000479	regulation of cAMP-dependent protein kinase activity
0.79	GO:0045761	regulation of adenylate cyclase activity
0.77	GO:0007218	neuropeptide signaling pathway
0.72	GO:0043408	regulation of MAPK cascade
0.47	GO:1901652	response to peptide
0.46	GO:0032870	cellular response to hormone stimulus
0.35	GO:0009582	detection of abiotic stimulus

0.83	GO:0031628	opioid receptor binding
0.79	GO:0008188	neuropeptide receptor activity
0.47	GO:0042277	peptide binding

0.49	GO:0015629	actin cytoskeleton
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y5X9|LIPE_HUMAN
Endothelial lipase
Search

LIPG

0.45	Endothelial lipase

0.63	GO:0006629	lipid metabolic process
0.59	GO:0010983	positive regulation of high-density lipoprotein particle clearance
0.57	GO:0050746	regulation of lipoprotein metabolic process
0.57	GO:0055091	phospholipid homeostasis
0.57	GO:0034375	high-density lipoprotein particle remodeling
0.57	GO:0043691	reverse cholesterol transport
0.57	GO:0032376	positive regulation of cholesterol transport
0.55	GO:0042632	cholesterol homeostasis
0.43	GO:1901575	organic substance catabolic process
0.40	GO:0007584	response to nutrient

0.85	GO:0004465	lipoprotein lipase activity
0.55	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.52	GO:0008201	heparin binding
0.35	GO:0033878	hormone-sensitive lipase activity
0.34	GO:0034185	apolipoprotein binding
0.33	GO:0005102	receptor binding

0.66	GO:0005576	extracellular region
0.53	GO:0005769	early endosome
0.51	GO:1990777	lipoprotein particle
0.51	GO:0009986	cell surface
0.49	GO:0031225	anchored component of membrane
0.49	GO:0005794	Golgi apparatus
0.40	GO:0005886	plasma membrane

0.85

EC:3.1.1.34

GO:0004465

sp|Q9Y5Y0|FLVC1_HUMAN
Feline leukemia virus subgroup C receptor-related protein 1
Search

FLVCR1

0.93	Feline leukemia virus subgroup C cellular receptor 1

0.62	GO:0097037	heme export
0.62	GO:0030218	erythrocyte differentiation
0.58	GO:0048536	spleen development
0.58	GO:0060323	head morphogenesis
0.57	GO:0042733	embryonic digit morphogenesis
0.57	GO:0035264	multicellular organism growth
0.56	GO:0046620	regulation of organ growth
0.56	GO:0048704	embryonic skeletal system morphogenesis
0.54	GO:0001568	blood vessel development
0.53	GO:0001701	in utero embryonic development

0.55	GO:0015232	heme transporter activity
0.37	GO:0020037	heme binding
0.36	GO:0104005	hijacked molecular function
0.34	GO:0005515	protein binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0016788	hydrolase activity, acting on ester bonds

0.45	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1

GO:0016788

sp|Q9Y5Y2|NUBP2_HUMAN
Cytosolic Fe-S cluster assembly factor NUBP2
Search

NUBP2

0.97	Cytosolic Fe-S cluster assembly factor NUBP2

0.70	GO:0016226	iron-sulfur cluster assembly
0.37	GO:0030030	cell projection organization
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.64	GO:0051539	4 iron, 4 sulfur cluster binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.33	GO:0004519	endonuclease activity
0.32	GO:0003677	DNA binding

0.55	GO:0005815	microtubule organizing center
0.50	GO:0000922	spindle pole
0.48	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.38	GO:0005929	cilium

sp|Q9Y5Y3|GPR45_HUMAN
Probable G-protein coupled receptor 45
Search

GPR45

0.92	High-affinity lysophosphatidic acid receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007399	nervous system development

0.72

GO:0004930

G-protein coupled receptor activity

0.49	GO:0043235	receptor complex
0.45	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q9Y5Y4|PD2R2_HUMAN
Prostaglandin D2 receptor 2
Search

PTGDR2

0.58	G-protein coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:2000255	negative regulation of male germ cell proliferation
0.58	GO:0019722	calcium-mediated signaling
0.57	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.52	GO:0006935	chemotaxis
0.47	GO:0007268	chemical synaptic transmission
0.45	GO:0002430	complement receptor mediated signaling pathway
0.43	GO:0050900	leukocyte migration
0.43	GO:1904646	cellular response to amyloid-beta
0.43	GO:0090026	positive regulation of monocyte chemotaxis

0.72	GO:0004930	G-protein coupled receptor activity
0.54	GO:0001653	peptide receptor activity
0.51	GO:0042923	neuropeptide binding
0.45	GO:0004875	complement receptor activity
0.44	GO:0005124	scavenger receptor binding
0.35	GO:0050786	RAGE receptor binding
0.34	GO:0038024	cargo receptor activity
0.33	GO:0004749	ribose phosphate diphosphokinase activity
0.33	GO:0000287	magnesium ion binding

0.47	GO:0043005	neuron projection
0.46	GO:0005887	integral component of plasma membrane
0.38	GO:0005622	intracellular
0.33	GO:0012506	vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system

0.33	EC:2.7.6.1	GO:0004749
0.33	KEGG:R01049	GO:0004749

sp|Q9Y5Y5|PEX16_HUMAN
Peroxisomal membrane protein PEX16
Search

PEX16

0.92	Peroxisomal biogenesis factor 16

0.87	GO:0016557	peroxisome membrane biogenesis
0.86	GO:0022615	protein to membrane docking
0.85	GO:0032581	ER-dependent peroxisome organization
0.85	GO:0045046	protein import into peroxisome membrane
0.79	GO:0016558	protein import into peroxisome matrix
0.72	GO:0070972	protein localization to endoplasmic reticulum

0.80

GO:0008022

protein C-terminus binding

0.79	GO:0031903	microbody membrane
0.78	GO:0044439	peroxisomal part
0.74	GO:0031301	integral component of organelle membrane
0.69	GO:0005789	endoplasmic reticulum membrane

sp|Q9Y5Y6|ST14_HUMAN
Suppressor of tumorigenicity 14 protein
Search

ST14

0.76	Suppressor of tumorigenicity 14 protein homolog

0.60	GO:0006508	proteolysis
0.60	GO:0060672	epithelial cell morphogenesis involved in placental branching
0.59	GO:0008544	epidermis development
0.58	GO:0043588	skin development
0.57	GO:0001843	neural tube closure
0.35	GO:0012501	programmed cell death
0.35	GO:0016477	cell migration
0.34	GO:0010951	negative regulation of endopeptidase activity

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0008201	heparin binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0046914	transition metal ion binding
0.32	GO:0005509	calcium ion binding

0.53	GO:0019897	extrinsic component of plasma membrane
0.48	GO:0005576	extracellular region
0.40	GO:0016323	basolateral plasma membrane
0.36	GO:0031982	vesicle
0.35	GO:0005887	integral component of plasma membrane

0.69

GO:0004252

sp|Q9Y5Y7|LYVE1_HUMAN
Lymphatic vessel endothelial hyaluronic acid receptor 1
Search

LYVE1

0.97	Lymphatic vessel endothelial hyaluronic acid receptor 1

0.71	GO:0007155	cell adhesion
0.58	GO:0006027	glycosaminoglycan catabolic process
0.49	GO:0007165	signal transduction
0.38	GO:0030212	hyaluronan metabolic process
0.37	GO:0009611	response to wounding
0.36	GO:0009653	anatomical structure morphogenesis
0.36	GO:0046395	carboxylic acid catabolic process

0.84	GO:0005540	hyaluronic acid binding
0.55	GO:0099600	transmembrane receptor activity
0.52	GO:0038023	signaling receptor activity
0.35	GO:0005515	protein binding

0.46	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y5Y9|SCNAA_HUMAN
Sodium channel protein type 10 subunit alpha
Search

SCN10A

0.62	Sodium channel protein type 10 subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0019233	sensory perception of pain
0.66	GO:0086043	bundle of His cell action potential
0.65	GO:0086016	AV node cell action potential
0.65	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.62	GO:0055117	regulation of cardiac muscle contraction
0.61	GO:0002027	regulation of heart rate
0.55	GO:0019228	neuronal action potential
0.55	GO:0086010	membrane depolarization during action potential

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.72	GO:0022839	ion gated channel activity
0.72	GO:0008381	mechanosensitive ion channel activity
0.61	GO:0044325	ion channel binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.42	GO:0044299	C-fiber
0.42	GO:0071439	clathrin complex
0.39	GO:0070062	extracellular exosome

sp|Q9Y5Z0|BACE2_HUMAN
Beta-secretase 2
Search

BACE2

0.97	Beta-site APP-cleaving enzyme 2

0.61	GO:0006509	membrane protein ectodomain proteolysis
0.60	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process
0.54	GO:0050435	amyloid-beta metabolic process
0.46	GO:0097324	melanocyte migration
0.44	GO:0030163	protein catabolic process
0.41	GO:0050804	modulation of chemical synaptic transmission
0.36	GO:0016486	peptide hormone processing

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.52	GO:0001540	amyloid-beta binding
0.39	GO:0019899	enzyme binding

0.53	GO:0005794	Golgi apparatus
0.42	GO:0005768	endosome
0.41	GO:0030424	axon
0.38	GO:0031984	organelle subcompartment
0.38	GO:0005887	integral component of plasma membrane
0.38	GO:0009986	cell surface
0.37	GO:0005783	endoplasmic reticulum

sp|Q9Y5Z4|HEBP2_HUMAN
Heme-binding protein 2
Search

HEBP2

0.93	Heme-binding protein 2

0.87	GO:0010917	negative regulation of mitochondrial membrane potential
0.86	GO:0010940	positive regulation of necrotic cell death
0.86	GO:0035794	positive regulation of mitochondrial membrane permeability
0.45	GO:1901031	regulation of response to reactive oxygen species
0.42	GO:0043312	neutrophil degranulation

0.37

GO:0005515

protein binding

0.60	GO:0005739	mitochondrion
0.44	GO:0070062	extracellular exosome
0.42	GO:0035578	azurophil granule lumen

sp|Q9Y5Z6|B3GT1_HUMAN
Beta-1,3-galactosyltransferase 1
Search

B3GALT1

0.57	Beta-1,3-galactosyltransferase 1

0.78	GO:0006682	galactosylceramide biosynthetic process
0.74	GO:0006486	protein glycosylation
0.67	GO:0030259	lipid glycosylation
0.62	GO:0009312	oligosaccharide biosynthetic process

0.87	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity
0.77	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

0.71	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.87

EC:2.4.1.86

GO:0047275

sp|Q9Y5Z7|HCFC2_HUMAN
Host cell factor 2
Search

HCFC2

0.95	Host cell factor 2

0.41	GO:0043982	histone H4-K8 acetylation
0.41	GO:0043981	histone H4-K5 acetylation
0.41	GO:0043984	histone H4-K16 acetylation
0.40	GO:0019045	latent virus replication
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0050821	protein stabilization
0.38	GO:0006366	transcription by RNA polymerase II
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.37	GO:0048522	positive regulation of cellular process
0.37	GO:0010557	positive regulation of macromolecule biosynthetic process

0.41	GO:0003713	transcription coactivator activity
0.41	GO:0043996	histone acetyltransferase activity (H4-K8 specific)
0.41	GO:0046972	histone acetyltransferase activity (H4-K16 specific)
0.41	GO:0043995	histone acetyltransferase activity (H4-K5 specific)
0.40	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.39	GO:0033613	activating transcription factor binding
0.39	GO:0003682	chromatin binding
0.39	GO:0045296	cadherin binding
0.38	GO:0030674	protein binding, bridging
0.37	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.52	GO:0005829	cytosol
0.50	GO:0048188	Set1C/COMPASS complex
0.45	GO:0005886	plasma membrane
0.39	GO:0043025	neuronal cell body
0.39	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.38	GO:0070461	SAGA-type complex
0.30	GO:0016021	integral component of membrane

sp|Q9Y5Z9|UBIA1_HUMAN
UbiA prenyltransferase domain-containing protein 1
Search

UBIAD1

0.97	UbiA prenyltransferase domain-containing protein 1

0.64	GO:0042371	vitamin K biosynthetic process
0.55	GO:0009234	menaquinone biosynthetic process
0.54	GO:0032194	ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate
0.50	GO:0098869	cellular oxidant detoxification
0.48	GO:0001885	endothelial cell development
0.45	GO:0072358	cardiovascular system development
0.45	GO:0071498	cellular response to fluid shear stress
0.41	GO:0035207	negative regulation of hemocyte proliferation
0.41	GO:0045614	negative regulation of plasmatocyte differentiation
0.41	GO:0035203	regulation of lamellocyte differentiation

0.71	GO:0004659	prenyltransferase activity
0.51	GO:0016209	antioxidant activity
0.44	GO:0004517	nitric-oxide synthase activity
0.33	GO:0005515	protein binding

0.58	GO:0030173	integral component of Golgi membrane
0.51	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0005739	mitochondrion
0.34	GO:0031967	organelle envelope

0.71

EC:2.5.1

GO:0004659

sp|Q9Y600|CSAD_HUMAN
Cysteine sulfinic acid decarboxylase
Search

CSAD

0.95	Cysteine sulfinic acid decarboxylase

0.67	GO:0046305	alkanesulfonate biosynthetic process
0.62	GO:0019530	taurine metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.44	GO:0007507	heart development
0.44	GO:1901566	organonitrogen compound biosynthetic process
0.35	GO:0044273	sulfur compound catabolic process
0.34	GO:0016054	organic acid catabolic process
0.34	GO:1901565	organonitrogen compound catabolic process
0.30	GO:0044238	primary metabolic process

0.68	GO:0016831	carboxy-lyase activity
0.66	GO:0070279	vitamin B6 binding
0.60	GO:0050662	coenzyme binding
0.52	GO:0043168	anion binding

0.34

GO:0005829

cytosol

0.68

EC:4.1.1

GO:0016831

sp|Q9Y603|ETV7_HUMAN
Transcription factor ETV7
Search

ETV7

0.92	Ets variant 7

0.62	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0030154	cell differentiation
0.41	GO:0030097	hemopoiesis
0.40	GO:0034101	erythrocyte homeostasis
0.38	GO:0097152	mesenchymal cell apoptotic process
0.38	GO:0007296	vitellogenesis
0.37	GO:0072089	stem cell proliferation
0.36	GO:0006366	transcription by RNA polymerase II
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0007399	nervous system development

0.65	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.62	GO:0001012	RNA polymerase II regulatory region DNA binding
0.58	GO:0003690	double-stranded DNA binding
0.37	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.55	GO:0031974	membrane-enclosed lumen
0.49	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol
0.34	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q9Y605|MOFA1_HUMAN
MORF4 family-associated protein 1
Search

MRFAP1

0.97	Mof4 family associated protein 1

0.40

GO:0006013

mannose metabolic process

0.63	GO:0042802	identical protein binding
0.40	GO:0004559	alpha-mannosidase activity
0.38	GO:0030246	carbohydrate binding

0.54	GO:0005829	cytosol
0.52	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005634	nucleus

0.40

EC:3.2.1.24

GO:0004559

sp|Q9Y606|TRUA_HUMAN
tRNA pseudouridine synthase A, mitochondrial
Search

PUS1

0.46	tRNA pseudouridine synthase A

0.71	GO:0001522	pseudouridine synthesis
0.65	GO:0008033	tRNA processing
0.47	GO:0016556	mRNA modification
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:1900864	mitochondrial RNA modification
0.36	GO:0000963	mitochondrial RNA processing
0.35	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding
0.37	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.35	GO:0004730	pseudouridylate synthase activity
0.33	GO:0005515	protein binding

0.46	GO:0005634	nucleus
0.45	GO:0005739	mitochondrion
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005667	transcription factor complex
0.35	GO:0000785	chromatin
0.30	GO:0031224	intrinsic component of membrane

0.72	EC:5.4.99.12	GO:0009982
0.35	KEGG:R01055	GO:0004730

sp|Q9Y608|LRRF2_HUMAN
Leucine-rich repeat flightless-interacting protein 2
Search

LRRFIP2

0.91	LRR binding FLII interacting protein 2

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.70

GO:0030275

LRR domain binding

sp|Q9Y613|FHOD1_HUMAN
FH1/FH2 domain-containing protein 1
Search

FHOD1

0.86	Formin homology 2 domain containing 1

0.81	GO:0051492	regulation of stress fiber assembly
0.61	GO:0051660	establishment of centrosome localization
0.57	GO:0007097	nuclear migration
0.57	GO:0032233	positive regulation of actin filament bundle assembly
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0007015	actin filament organization
0.36	GO:0055003	cardiac myofibril assembly
0.36	GO:0045214	sarcomere organization
0.36	GO:0030837	negative regulation of actin filament polymerization

0.57	GO:0043621	protein self-association
0.53	GO:0019904	protein domain specific binding
0.51	GO:0042802	identical protein binding
0.37	GO:0003779	actin binding

0.58	GO:0014704	intercalated disc
0.57	GO:0097517	contractile actin filament bundle
0.57	GO:0042641	actomyosin
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.39	GO:0032059	bleb
0.36	GO:0030017	sarcomere
0.35	GO:0005912	adherens junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y614|ACL7B_HUMAN
Actin-like protein 7B
Search

0.97	Testicular secretory protein Li 3

0.38

GO:0007010

cytoskeleton organization

0.39	GO:0005200	structural constituent of cytoskeleton
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.64	GO:0001673	male germ cell nucleus
0.59	GO:0031514	motile cilium
0.55	GO:0005794	Golgi apparatus
0.48	GO:0043234	protein complex
0.47	GO:0005856	cytoskeleton
0.33	GO:0044446	intracellular organelle part

sp|Q9Y615|ACL7A_HUMAN
Actin-like protein 7A
Search

0.97	Testicular secretory protein Li 3

0.37	GO:0007010	cytoskeleton organization
0.34	GO:0051591	response to cAMP
0.34	GO:0006909	phagocytosis
0.34	GO:0000902	cell morphogenesis
0.33	GO:0033572	transferrin transport

0.42	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0005515	protein binding
0.33	GO:0033570	transferrin transmembrane transporter activity
0.30	GO:0003824	catalytic activity

0.62	GO:0001673	male germ cell nucleus
0.58	GO:0031514	motile cilium
0.53	GO:0005794	Golgi apparatus
0.47	GO:0043234	protein complex
0.45	GO:0005856	cytoskeleton
0.35	GO:0031982	vesicle
0.35	GO:0043230	extracellular organelle
0.35	GO:0061836	intranuclear rod
0.35	GO:0060187	cell pole
0.35	GO:0005615	extracellular space

sp|Q9Y616|IRAK3_HUMAN
Interleukin-1 receptor-associated kinase 3
Search

IRAK3

0.97	Interleukin-1 receptor-associated kinase 3

0.85	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.81	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.75	GO:0010932	regulation of macrophage tolerance induction
0.72	GO:0002645	positive regulation of tolerance induction
0.72	GO:0010936	negative regulation of macrophage cytokine production
0.71	GO:0032494	response to peptidoglycan
0.71	GO:0032695	negative regulation of interleukin-12 production
0.71	GO:0045824	negative regulation of innate immune response
0.70	GO:0070498	interleukin-1-mediated signaling pathway
0.69	GO:0032715	negative regulation of interleukin-6 production

0.64	GO:0004672	protein kinase activity
0.60	GO:0042803	protein homodimerization activity
0.60	GO:0046982	protein heterodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0000287	magnesium ion binding
0.35	GO:0030246	carbohydrate binding
0.35	GO:0001871	pattern binding
0.34	GO:0005509	calcium ion binding

0.52	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q9Y617|SERC_HUMAN
Phosphoserine aminotransferase
Search

PSAT1

0.51	Phosphoserine aminotransferase

0.75	GO:0006564	L-serine biosynthetic process
0.34	GO:0008615	pyridoxine biosynthetic process

0.78

GO:0004648

O-phospho-L-serine:2-oxoglutarate aminotransferase activity

0.48	GO:0005829	cytosol
0.40	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.6.1.52

GO:0004648

sp|Q9Y618|NCOR2_HUMAN
Nuclear receptor corepressor 2
Search

NCOR2

0.94	LOW QUALITY PROTEIN: nuclear receptor corepressor 2

0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0044849	estrous cycle
0.42	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA
0.42	GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter
0.41	GO:0007595	lactation
0.41	GO:0032355	response to estradiol
0.39	GO:0010243	response to organonitrogen compound
0.39	GO:0060509	Type I pneumocyte differentiation
0.38	GO:0050872	white fat cell differentiation
0.38	GO:0090312	positive regulation of protein deacetylation

0.54	GO:0003677	DNA binding
0.51	GO:0016922	ligand-dependent nuclear receptor binding
0.46	GO:0003714	transcription corepressor activity
0.42	GO:0035259	glucocorticoid receptor binding
0.42	GO:0046965	retinoid X receptor binding
0.41	GO:0005112	Notch binding
0.41	GO:0047485	protein N-terminus binding
0.41	GO:0042826	histone deacetylase binding
0.40	GO:0003682	chromatin binding
0.39	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.40	GO:0017053	transcriptional repressor complex
0.40	GO:1902494	catalytic complex
0.39	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|Q9Y619|ORNT1_HUMAN
Mitochondrial ornithine transporter 1
Search

SLC25A15

0.92	Mitochondrial ornithine transporter 1

0.53	GO:0000066	mitochondrial ornithine transport
0.52	GO:1903352	L-ornithine transmembrane transport
0.37	GO:0000050	urea cycle
0.34	GO:0006367	transcription initiation from RNA polymerase II promoter

0.52

GO:0000064

L-ornithine transmembrane transporter activity

0.45	GO:0005739	mitochondrion
0.44	GO:0019866	organelle inner membrane
0.34	GO:0005669	transcription factor TFIID complex
0.30	GO:0016021	integral component of membrane

sp|Q9Y620|RA54B_HUMAN
DNA repair and recombination protein RAD54B
Search

RAD54B

0.86	LOW QUALITY PROTEIN: DNA repair and recombination protein RAD54B

0.58	GO:0008340	determination of adult lifespan
0.57	GO:0010212	response to ionizing radiation
0.55	GO:0000724	double-strand break repair via homologous recombination
0.51	GO:0042493	response to drug
0.36	GO:0006312	mitotic recombination
0.36	GO:0007131	reciprocal meiotic recombination
0.35	GO:0007165	signal transduction
0.35	GO:0032392	DNA geometric change
0.33	GO:0001731	formation of translation preinitiation complex
0.33	GO:0006446	regulation of translational initiation

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0015616	DNA translocase activity
0.36	GO:0004386	helicase activity
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0005515	protein binding
0.35	GO:0003677	DNA binding

0.36	GO:0005634	nucleus
0.33	GO:0016282	eukaryotic 43S preinitiation complex
0.33	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0005852	eukaryotic translation initiation factor 3 complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.31

GO:0016740

sp|Q9Y623|MYH4_HUMAN
Myosin-4
Search

0.77	Myosin, heavy polypeptide 8, skeletal muscle, perinatal

0.74	GO:0007018	microtubule-based movement
0.56	GO:0006936	muscle contraction
0.54	GO:0070252	actin-mediated cell contraction
0.53	GO:0014823	response to activity
0.49	GO:0050881	musculoskeletal movement
0.45	GO:0001778	plasma membrane repair
0.41	GO:0046034	ATP metabolic process
0.39	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0000146	microfilament motor activity
0.46	GO:0005516	calmodulin binding
0.42	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.49	GO:0014704	intercalated disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0005826	actomyosin contractile ring
0.41	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.42

GO:0016887

sp|Q9Y624|JAM1_HUMAN
Junctional adhesion molecule A
Search

F11R

0.87	Junctional adhesion molecule A

0.62	GO:0090557	establishment of endothelial intestinal barrier
0.62	GO:0050892	intestinal absorption
0.60	GO:0034260	negative regulation of GTPase activity
0.60	GO:2000249	regulation of actin cytoskeleton reorganization
0.60	GO:0090559	regulation of membrane permeability
0.58	GO:0072659	protein localization to plasma membrane
0.57	GO:0031032	actomyosin structure organization
0.56	GO:0001817	regulation of cytokine production
0.54	GO:0043547	positive regulation of GTPase activity
0.52	GO:0007155	cell adhesion

0.59	GO:0030165	PDZ domain binding
0.57	GO:0045296	cadherin binding
0.42	GO:0046982	protein heterodimerization activity
0.37	GO:0104005	hijacked molecular function
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005044	scavenger receptor activity
0.32	GO:0004860	protein kinase inhibitor activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005923	bicellular tight junction
0.44	GO:0005886	plasma membrane
0.44	GO:0036057	slit diaphragm
0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0070062	extracellular exosome
0.32	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|Q9Y625|GPC6_HUMAN
Glypican-6
Search

GPC6

0.82	Glypican 6

0.70	GO:0009966	regulation of signal transduction
0.46	GO:0016477	cell migration
0.36	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.36	GO:0001523	retinoid metabolic process
0.35	GO:0060028	convergent extension involved in axis elongation
0.35	GO:0036342	post-anal tail morphogenesis
0.35	GO:0060027	convergent extension involved in gastrulation
0.35	GO:0030903	notochord development
0.35	GO:0001702	gastrulation with mouth forming second
0.35	GO:0009826	unidimensional cell growth

0.81	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

0.83	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0005615	extracellular space
0.40	GO:0009897	external side of plasma membrane
0.38	GO:0005796	Golgi lumen
0.36	GO:0043202	lysosomal lumen
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

sp|Q9Y639|NPTN_HUMAN
Neuroplastin
Search

NPTN

0.96	Stromal cell-derived receptor 1

0.60	GO:1902683	regulation of receptor localization to synapse
0.59	GO:1904861	excitatory synapse assembly
0.54	GO:0050804	modulation of chemical synaptic transmission
0.39	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.38	GO:0010976	positive regulation of neuron projection development
0.38	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.38	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0001934	positive regulation of protein phosphorylation
0.37	GO:0008542	visual learning
0.37	GO:0070372	regulation of ERK1 and ERK2 cascade

0.40	GO:0005105	type 1 fibroblast growth factor receptor binding
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0044325	ion channel binding

0.54	GO:0030425	dendrite
0.39	GO:0042734	presynaptic membrane
0.38	GO:0060077	inhibitory synapse
0.37	GO:0014069	postsynaptic density
0.36	GO:0009986	cell surface
0.35	GO:0045211	postsynaptic membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y644|RFNG_HUMAN
Beta-1,3-N-acetylglucosaminyltransferase radical fringe
Search

RFNG

0.84	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

0.69	GO:0007389	pattern specification process
0.57	GO:0036066	protein O-linked fucosylation
0.54	GO:0045747	positive regulation of Notch signaling pathway
0.54	GO:0032092	positive regulation of protein binding
0.44	GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis
0.43	GO:0030154	cell differentiation
0.43	GO:0048731	system development
0.42	GO:0002312	B cell activation involved in immune response
0.42	GO:0051446	positive regulation of meiotic cell cycle
0.42	GO:0009790	embryo development

0.79	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.46	GO:0046872	metal ion binding
0.34	GO:0016491	oxidoreductase activity

0.71	GO:0030173	integral component of Golgi membrane
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005615	extracellular space

0.79

EC:2.4.1.222

GO:0033829

sp|Q9Y646|CBPQ_HUMAN
Carboxypeptidase Q
Search

CPQ

0.87	Carboxypeptidase Q

0.59	GO:0006508	proteolysis
0.56	GO:0043171	peptide catabolic process
0.53	GO:0006590	thyroid hormone generation
0.44	GO:0042246	tissue regeneration

0.67	GO:0008238	exopeptidase activity
0.55	GO:0042803	protein homodimerization activity
0.51	GO:0008237	metallopeptidase activity
0.37	GO:0046872	metal ion binding

0.54	GO:0005615	extracellular space
0.53	GO:0005794	Golgi apparatus
0.44	GO:0005764	lysosome
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y651|SOX21_HUMAN
Transcription factor SOX-21
Search

SOX21

0.81	Transcription factor SOX-21

0.52	GO:0048731	system development
0.51	GO:0048863	stem cell differentiation
0.49	GO:0060429	epithelium development
0.49	GO:0022405	hair cycle process
0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0006366	transcription by RNA polymerase II
0.48	GO:0010468	regulation of gene expression
0.47	GO:0008544	epidermis development
0.47	GO:1902680	positive regulation of RNA biosynthetic process

0.55	GO:0003677	DNA binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q9Y653|AGRG1_HUMAN
Adhesion G-protein coupled receptor G1
Search

ADGRG1

0.92	LOW QUALITY PROTEIN: G-protein coupled receptor 56

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0021796	cerebral cortex regionalization
0.45	GO:2001223	negative regulation of neuron migration
0.45	GO:0021819	layer formation in cerebral cortex
0.45	GO:0072520	seminiferous tubule development
0.44	GO:0035025	positive regulation of Rho protein signal transduction
0.44	GO:2000179	positive regulation of neural precursor cell proliferation
0.42	GO:0010573	vascular endothelial growth factor production
0.42	GO:0070528	protein kinase C signaling

0.72	GO:0004930	G-protein coupled receptor activity
0.44	GO:0050840	extracellular matrix binding
0.43	GO:0005518	collagen binding
0.43	GO:0008201	heparin binding

0.46	GO:0097451	glial limiting end-foot
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q9Y657|SPIN1_HUMAN
Spindlin-1
Search

SPIN1

0.97	Z-linked spindlin 1

0.78	GO:0007276	gamete generation
0.49	GO:0009303	rRNA transcription
0.48	GO:0030177	positive regulation of Wnt signaling pathway
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0051321	meiotic cell cycle
0.37	GO:0016055	Wnt signaling pathway
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0007275	multicellular organism development
0.34	GO:0046294	formaldehyde catabolic process
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism

0.50	GO:0140034	methylation-dependent protein binding
0.48	GO:0042393	histone binding
0.34	GO:0018738	S-formylglutathione hydrolase activity
0.34	GO:0003677	DNA binding
0.33	GO:0052689	carboxylic ester hydrolase activity

0.47	GO:0031965	nuclear membrane
0.45	GO:0005819	spindle
0.45	GO:0005730	nucleolus
0.43	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol

0.34	EC:3.1.2.12	GO:0018738
0.34	KEGG:R00527	GO:0018738

sp|Q9Y661|HS3S4_HUMAN
Heparan sulfate glucosamine 3-O-sulfotransferase 4
Search

0.63	Heparan sulfate glucosamine 3-O-sulfotransferase 4

0.70	GO:0007623	circadian rhythm
0.67	GO:0030201	heparan sulfate proteoglycan metabolic process
0.48	GO:0006024	glycosaminoglycan biosynthetic process

0.85

GO:0034483

heparan sulfate sulfotransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y662|HS3SB_HUMAN
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1
Search

0.56	Sulfotransferase

0.35

GO:0006477

protein sulfation

0.78

GO:0008146

sulfotransferase activity

0.34

GO:0005887

integral component of plasma membrane

0.78

GO:0008146

sp|Q9Y663|HS3SA_HUMAN
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1
Search

0.56	Sulfotransferase

0.34

GO:0006477

protein sulfation

0.78

GO:0008146

sulfotransferase activity

0.33

GO:0005887

integral component of plasma membrane

0.78

GO:0008146

sp|Q9Y664|KPTN_HUMAN
Kaptin
Search

KPTN

0.96	KICSTOR complex protein kaptin

0.74	GO:0007015	actin filament organization
0.61	GO:0061462	protein localization to lysosome
0.61	GO:1904262	negative regulation of TORC1 signaling
0.59	GO:0034198	cellular response to amino acid starvation
0.59	GO:0042149	cellular response to glucose starvation
0.38	GO:0035725	sodium ion transmembrane transport
0.38	GO:0006816	calcium ion transport
0.30	GO:0008152	metabolic process

0.73	GO:0003779	actin binding
0.54	GO:0032403	protein complex binding
0.39	GO:0005432	calcium:sodium antiporter activity
0.30	GO:0003824	catalytic activity

0.73	GO:0015629	actin cytoskeleton
0.64	GO:0099571	postsynaptic cytoskeleton
0.63	GO:0140007	KICSTOR complex
0.58	GO:0030027	lamellipodium
0.52	GO:0099513	polymeric cytoskeletal fiber
0.46	GO:0043234	protein complex
0.40	GO:0032420	stereocilium
0.39	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y666|S12A7_HUMAN
Solute carrier family 12 member 7
Search

SLC12A7

0.85	Solute carrier family 12 (Potassium/chloride transporters), member 7

0.79	GO:0006884	cell volume homeostasis
0.75	GO:1902476	chloride transmembrane transport
0.53	GO:0007268	chemical synaptic transmission
0.44	GO:0071805	potassium ion transmembrane transport
0.43	GO:0030644	cellular chloride ion homeostasis
0.42	GO:0040040	thermosensory behavior
0.42	GO:0060996	dendritic spine development
0.41	GO:0006971	hypotonic response
0.41	GO:0035264	multicellular organism growth
0.41	GO:0007612	learning

0.85	GO:0015379	potassium:chloride symporter activity
0.49	GO:0019901	protein kinase binding
0.47	GO:0022820	potassium ion symporter activity

0.65	GO:0005887	integral component of plasma membrane
0.41	GO:0043198	dendritic shaft
0.40	GO:0043025	neuronal cell body

sp|Q9Y672|ALG6_HUMAN
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
Search

ALG6

0.60	Alpha-1,3-glucosyltransferase

0.74	GO:0006486	protein glycosylation
0.46	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process
0.36	GO:0040003	chitin-based cuticle development
0.34	GO:0008299	isoprenoid biosynthetic process
0.33	GO:0016310	phosphorylation

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.35	GO:0004496	mevalonate kinase activity
0.33	GO:0008080	N-acetyltransferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.69	EC:2.4.1	GO:0016758
0.35	KEGG:R02245	GO:0004496

sp|Q9Y673|ALG5_HUMAN
Dolichyl-phosphate beta-glucosyltransferase
Search

ALG5

0.81	Dolichyl-phosphate beta-glucosyltransferase

0.56	GO:0007368	determination of left/right symmetry
0.49	GO:0006487	protein N-linked glycosylation
0.39	GO:0007509	mesoderm migration involved in gastrulation
0.38	GO:0019991	septate junction assembly
0.38	GO:0001703	gastrulation with mouth forming first
0.38	GO:0040003	chitin-based cuticle development
0.37	GO:0009953	dorsal/ventral pattern formation
0.37	GO:0007029	endoplasmic reticulum organization
0.37	GO:0007030	Golgi organization
0.37	GO:0007009	plasma membrane organization

0.48	GO:0016740	transferase activity
0.33	GO:0003712	transcription cofactor activity
0.32	GO:0046872	metal ion binding

0.45	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0031984	organelle subcompartment
0.33	GO:0000124	SAGA complex
0.30	GO:0031224	intrinsic component of membrane

0.48

GO:0016740

sp|Q9Y675|SNURF_HUMAN
SNRPN upstream reading frame protein
Search

SNURF

0.97	SNRPN upstream reading frame protein isoform X2

0.63

GO:0051117

ATPase binding

0.61	GO:0005634	nucleus
0.52	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part

sp|Q9Y676|RT18B_HUMAN
28S ribosomal protein S18b, mitochondrial
Search

MRPS18B

0.97	Mitochondrial ribosomal protein S18B

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly
0.34	GO:0055114	oxidation-reduction process

0.63	GO:0003735	structural constituent of ribosome
0.35	GO:0016491	oxidoreductase activity
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.56	GO:0005759	mitochondrial matrix
0.55	GO:0030054	cell junction
0.52	GO:0005654	nucleoplasm
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

0.35

GO:0016491

sp|Q9Y678|COPG1_HUMAN
Coatomer subunit gamma-1
Search

COPG1

0.70	Coatomer subunit gamma

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.37	GO:0051683	establishment of Golgi localization
0.36	GO:0072384	organelle transport along microtubule

0.62	GO:0005198	structural molecule activity
0.34	GO:0005515	protein binding
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.81	GO:0030126	COPI vesicle coat
0.67	GO:0000139	Golgi membrane
0.37	GO:0030133	transport vesicle
0.36	GO:0005829	cytosol
0.36	GO:0099503	secretory vesicle
0.34	GO:0005789	endoplasmic reticulum membrane

0.32

GO:0016757

sp|Q9Y679|AUP1_HUMAN
Ancient ubiquitous protein 1
Search

AUP1

0.96	Ancient ubiquitous protein 1

0.62	GO:1903513	endoplasmic reticulum to cytosol transport
0.62	GO:0032527	protein exit from endoplasmic reticulum
0.60	GO:0036503	ERAD pathway
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.43	GO:0050790	regulation of catalytic activity
0.35	GO:0016579	protein deubiquitination

0.48	GO:0097027	ubiquitin-protein transferase activator activity
0.47	GO:0043130	ubiquitin binding
0.36	GO:0016746	transferase activity, transferring acyl groups
0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.49	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex
0.46	GO:0030176	integral component of endoplasmic reticulum membrane
0.39	GO:0070062	extracellular exosome

0.36

GO:0016746

sp|Q9Y680|FKBP7_HUMAN
Peptidyl-prolyl cis-trans isomerase FKBP7
Search

FKBP7

0.62	Peptidyl-prolyl cis-trans isomerase FKBP7

0.74	GO:0061077	chaperone-mediated protein folding
0.68	GO:0000413	protein peptidyl-prolyl isomerization

0.80	GO:0005528	FK506 binding
0.70	GO:0005509	calcium ion binding
0.68	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.60	GO:0005515	protein binding

0.78

GO:0005788

endoplasmic reticulum lumen

0.68

GO:0003755

sp|Q9Y689|ARL5A_HUMAN
ADP-ribosylation factor-like protein 5A
Search

ARL5A

0.97	ADP ribosylation factor like GTPase 5A

0.56	GO:1903292	protein localization to Golgi membrane
0.35	GO:0070588	calcium ion transmembrane transport

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003779	actin binding
0.35	GO:0005245	voltage-gated calcium channel activity

0.45	GO:0005622	intracellular
0.35	GO:0005891	voltage-gated calcium channel complex

sp|Q9Y691|KCMB2_HUMAN
Calcium-activated potassium channel subunit beta-2
Search

KCNMB2

0.97	Calcium-activated potassium channel subunit beta-2

0.73	GO:0071805	potassium ion transmembrane transport
0.51	GO:0005513	detection of calcium ion
0.46	GO:0007268	chemical synaptic transmission
0.42	GO:0065009	regulation of molecular function
0.41	GO:0019228	neuronal action potential
0.35	GO:0019229	regulation of vasoconstriction
0.32	GO:0006508	proteolysis

0.84	GO:0015269	calcium-activated potassium channel activity
0.49	GO:0015459	potassium channel regulator activity
0.35	GO:0008200	ion channel inhibitor activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.46

GO:0008076

voltage-gated potassium channel complex

0.33

GO:0004222

sp|Q9Y692|GMEB1_HUMAN
Glucocorticoid modulatory element-binding protein 1
Search

GMEB1

0.97	Glucocorticoid modulatory element binding protein 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0006366	transcription by RNA polymerase II
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0010628	positive regulation of gene expression
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.79	GO:0003713	transcription coactivator activity
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y693|LHFP_HUMAN
Lipoma HMGIC fusion partner
Search

0.92	LHFPL tetraspan subfamily member 6

0.30

GO:0044425

membrane part

sp|Q9Y694|S22A7_HUMAN
Solute carrier family 22 member 7
Search

SLC22A7

0.97	LOW QUALITY PROTEIN: solute carrier family 22 member 7

0.55	GO:0055085	transmembrane transport
0.54	GO:0043252	sodium-independent organic anion transport
0.46	GO:0015698	inorganic anion transport
0.46	GO:0015747	urate transport
0.45	GO:2001142	nicotinate transport
0.38	GO:0035634	response to stilbenoid
0.34	GO:0046415	urate metabolic process
0.34	GO:0015695	organic cation transport
0.34	GO:0031427	response to methotrexate
0.33	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway

0.54	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.52	GO:0005452	inorganic anion exchanger activity
0.45	GO:0090416	nicotinate transmembrane transporter activity
0.37	GO:0015143	urate transmembrane transporter activity
0.36	GO:0015301	anion:anion antiporter activity
0.35	GO:0005515	protein binding
0.34	GO:0015101	organic cation transmembrane transporter activity
0.33	GO:0008519	ammonium transmembrane transporter activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.47	GO:0098590	plasma membrane region
0.45	GO:0005887	integral component of plasma membrane
0.42	GO:0045177	apical part of cell
0.34	GO:0070062	extracellular exosome

sp|Q9Y696|CLIC4_HUMAN
Chloride intracellular channel protein 4
Search

CLIC4

0.83	Chloride intracellular channel protein 4

0.75	GO:0034765	regulation of ion transmembrane transport
0.75	GO:1902476	chloride transmembrane transport
0.55	GO:0061299	retina vasculature morphogenesis in camera-type eye
0.55	GO:0001886	endothelial cell morphogenesis
0.53	GO:0007035	vacuolar acidification
0.53	GO:0030216	keratinocyte differentiation
0.52	GO:0071277	cellular response to calcium ion
0.52	GO:0035264	multicellular organism growth
0.52	GO:0001525	angiogenesis
0.52	GO:0048754	branching morphogenesis of an epithelial tube

0.76	GO:0005254	chloride channel activity
0.72	GO:0022832	voltage-gated channel activity
0.70	GO:0022839	ion gated channel activity
0.70	GO:0008381	mechanosensitive ion channel activity
0.46	GO:0004364	glutathione transferase activity
0.35	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.80	GO:0034707	chloride channel complex
0.52	GO:0005902	microvillus
0.52	GO:0016363	nuclear matrix
0.51	GO:0030496	midbody
0.50	GO:0045177	apical part of cell
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005813	centrosome
0.48	GO:0005911	cell-cell junction
0.48	GO:0009986	cell surface
0.45	GO:0005829	cytosol

0.46

EC:2.5.1.18

GO:0004364

sp|Q9Y697|NFS1_HUMAN
Cysteine desulfurase, mitochondrial
Search

NFS1

0.68	LOW QUALITY PROTEIN: cysteine desulfurase, mitochondrial

0.82	GO:0044571	[2Fe-2S] cluster assembly
0.56	GO:0018283	iron incorporation into metallo-sulfur cluster
0.37	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.34	GO:0032324	molybdopterin cofactor biosynthetic process
0.34	GO:0000096	sulfur amino acid metabolic process
0.34	GO:0006461	protein complex assembly

0.78	GO:0031071	cysteine desulfurase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.40	GO:0042803	protein homodimerization activity
0.36	GO:0051536	iron-sulfur cluster binding
0.34	GO:0046872	metal ion binding
0.34	GO:0016829	lyase activity
0.33	GO:0003723	RNA binding
0.33	GO:0004386	helicase activity
0.32	GO:0005524	ATP binding

0.49	GO:0005759	mitochondrial matrix
0.44	GO:0005634	nucleus
0.39	GO:0005829	cytosol

0.78

EC:2.8.1.7

GO:0031071

sp|Q9Y698|CCG2_HUMAN
Voltage-dependent calcium channel gamma-2 subunit
Search

CACNG2

0.47	Multifunctional fusion protein (Fragment)

0.70	GO:0034765	regulation of ion transmembrane transport
0.69	GO:0070588	calcium ion transmembrane transport
0.56	GO:0098953	receptor diffusion trapping
0.55	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome
0.55	GO:0099590	neurotransmitter receptor internalization
0.54	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.54	GO:0060081	membrane hyperpolarization
0.54	GO:1900449	regulation of glutamate receptor signaling pathway
0.54	GO:0099601	regulation of neurotransmitter receptor activity
0.54	GO:0019226	transmission of nerve impulse

0.73	GO:0005245	voltage-gated calcium channel activity
0.43	GO:0016247	channel regulator activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0003677	DNA binding

0.72	GO:0005891	voltage-gated calcium channel complex
0.54	GO:0032281	AMPA glutamate receptor complex
0.54	GO:0099634	postsynaptic specialization membrane
0.50	GO:0036477	somatodendritic compartment
0.36	GO:0005622	intracellular
0.35	GO:0014069	postsynaptic density

sp|Q9Y6A1|POMT1_HUMAN
Protein O-mannosyl-transferase 1
Search

POMT1

0.96	Protein O-mannosyl-transferase 1 isoform b

0.77	GO:0006493	protein O-linked glycosylation
0.76	GO:0097502	mannosylation
0.55	GO:0030198	extracellular matrix organization
0.50	GO:0071712	ER-associated misfolded protein catabolic process
0.41	GO:1904098	regulation of protein O-linked glycosylation
0.40	GO:0060050	positive regulation of protein glycosylation
0.35	GO:0007275	multicellular organism development
0.34	GO:0005975	carbohydrate metabolic process

0.76	GO:0000030	mannosyltransferase activity
0.33	GO:0046872	metal ion binding

0.57	GO:0016529	sarcoplasmic reticulum
0.57	GO:0001669	acrosomal vesicle
0.52	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.76

GO:0000030

sp|Q9Y6A2|CP46A_HUMAN
Cholesterol 24-hydroxylase
Search

CYP46A1

0.96	Cholesterol 24-hydroxylase

0.59	GO:0006707	cholesterol catabolic process
0.53	GO:0006805	xenobiotic metabolic process
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0006699	bile acid biosynthetic process
0.35	GO:0007399	nervous system development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.62	GO:0004497	monooxygenase activity

0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q9Y6A4|CFA20_HUMAN
Cilia- and flagella-associated protein 20
Search

CFAP20

0.89	Transcription factor IIB

0.81	GO:0060296	regulation of cilium beat frequency involved in ciliary motility
0.80	GO:2000253	positive regulation of feeding behavior
0.77	GO:0018095	protein polyglutamylation
0.72	GO:2000147	positive regulation of cell motility
0.71	GO:0060271	cilium assembly
0.39	GO:1901207	regulation of heart looping
0.39	GO:0014807	regulation of somitogenesis
0.38	GO:0065001	specification of axis polarity
0.36	GO:0006468	protein phosphorylation

0.36	GO:0004672	protein kinase activity
0.36	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0005929	cilium
0.73	GO:0005814	centriole
0.68	GO:0120038	plasma membrane bounded cell projection part
0.56	GO:0005634	nucleus
0.46	GO:0005874	microtubule
0.39	GO:0070062	extracellular exosome

sp|Q9Y6A5|TACC3_HUMAN
Transforming acidic coiled-coil-containing protein 3
Search

TACC3

0.88	Transforming acidic coiled-coil-containing protein 3

0.85	GO:0007091	metaphase/anaphase transition of mitotic cell cycle
0.80	GO:0060236	regulation of mitotic spindle organization
0.77	GO:1902850	microtubule cytoskeleton organization involved in mitosis
0.70	GO:0021987	cerebral cortex development
0.66	GO:0008283	cell proliferation
0.45	GO:0030953	astral microtubule organization
0.45	GO:0042994	cytoplasmic sequestering of transcription factor
0.44	GO:0051301	cell division
0.44	GO:0007097	nuclear migration
0.43	GO:0001666	response to hypoxia

0.43

GO:0005515

protein binding

0.75	GO:0072686	mitotic spindle
0.71	GO:0005815	microtubule organizing center
0.64	GO:0005829	cytosol
0.48	GO:0000922	spindle pole
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q9Y6A9|SPCS1_HUMAN
Signal peptidase complex subunit 1
Search

SPCS1

0.95	Signal peptidase complex subunit 1

0.80	GO:0006465	signal peptide processing
0.46	GO:0045047	protein targeting to ER
0.33	GO:0006412	translation

0.61	GO:0008233	peptidase activity
0.49	GO:0043022	ribosome binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.82	GO:0005787	signal peptidase complex
0.47	GO:0030176	integral component of endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.34	GO:0015934	large ribosomal subunit

0.61

GO:0008233

sp|Q9Y6B2|EID1_HUMAN
EP300-interacting inhibitor of differentiation 1
Search

EID1

0.97	Histone acetyltransferase-interacting inhibitor of differentiation (Fragment)

0.84	GO:0035065	regulation of histone acetylation
0.78	GO:0000122	negative regulation of transcription by RNA polymerase II
0.76	GO:0045595	regulation of cell differentiation
0.52	GO:0030154	cell differentiation
0.39	GO:0007049	cell cycle
0.37	GO:0006351	transcription, DNA-templated

0.63	GO:0035034	histone acetyltransferase regulator activity
0.60	GO:0035035	histone acetyltransferase binding
0.55	GO:0003714	transcription corepressor activity
0.34	GO:0016740	transferase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.61	GO:0005634	nucleus
0.55	GO:0036464	cytoplasmic ribonucleoprotein granule
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

0.34

GO:0016740

sp|Q9Y6B6|SAR1B_HUMAN
GTP-binding protein SAR1b
Search

SAR1B

0.81	GTP-binding protein SAR1b

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.38	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.37	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.37	GO:0051650	establishment of vesicle localization
0.36	GO:0016050	vesicle organization
0.35	GO:0006461	protein complex assembly
0.35	GO:0061024	membrane organization

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0003924	GTPase activity

0.71	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0098588	bounding membrane of organelle
0.42	GO:0031984	organelle subcompartment
0.36	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.36	GO:0030133	transport vesicle
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0098805	whole membrane
0.35	GO:0005829	cytosol

sp|Q9Y6B7|AP4B1_HUMAN
AP-4 complex subunit beta-1
Search

AP4B1

0.64	AP complex subunit beta

0.68	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.37	GO:0061938	protein localization to somatodendritic compartment
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0042981	regulation of apoptotic process

0.74	GO:0030276	clathrin binding
0.35	GO:0004725	protein tyrosine phosphatase activity

0.75	GO:0030131	clathrin adaptor complex
0.59	GO:0030124	AP-4 adaptor complex
0.54	GO:0005802	trans-Golgi network
0.52	GO:0019898	extrinsic component of membrane
0.49	GO:0005829	cytosol
0.36	GO:0031904	endosome lumen
0.35	GO:0000139	Golgi membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004725

sp|Q9Y6C2|EMIL1_HUMAN
EMILIN-1
Search

EMILIN1

0.97	Elastin microfibril interfacer 1

0.66	GO:0010811	positive regulation of cell-substrate adhesion
0.63	GO:0030198	extracellular matrix organization
0.50	GO:0007155	cell adhesion
0.44	GO:0070207	protein homotrimerization
0.42	GO:0016477	cell migration
0.40	GO:0030097	hemopoiesis
0.36	GO:0035987	endodermal cell differentiation
0.35	GO:0050673	epithelial cell proliferation
0.35	GO:0048593	camera-type eye morphogenesis
0.33	GO:0035556	intracellular signal transduction

0.74	GO:0030023	extracellular matrix constituent conferring elasticity
0.59	GO:0042802	identical protein binding
0.46	GO:0098640	integrin binding involved in cell-matrix adhesion
0.36	GO:0042302	structural constituent of cuticle
0.33	GO:0005044	scavenger receptor activity
0.32	GO:0001664	G-protein coupled receptor binding
0.32	GO:0004867	serine-type endopeptidase inhibitor activity

0.76	GO:0005581	collagen trimer
0.65	GO:0005576	extracellular region
0.47	GO:0034668	integrin alpha4-beta1 complex
0.47	GO:0098637	protein complex involved in cell-matrix adhesion
0.39	GO:0031982	vesicle
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.32	GO:0099080	supramolecular complex
0.31	GO:0019867	outer membrane
0.31	GO:0043233	organelle lumen

sp|Q9Y6C5|PTC2_HUMAN
Protein patched homolog 2
Search

PTCH2

0.90

Patched 2

0.65	GO:0009957	epidermal cell fate specification
0.63	GO:0045606	positive regulation of epidermal cell differentiation
0.61	GO:0001709	cell fate determination
0.60	GO:0007165	signal transduction
0.56	GO:0042633	hair cycle
0.56	GO:0043588	skin development
0.49	GO:0045879	negative regulation of smoothened signaling pathway
0.49	GO:0021997	neural plate axis specification
0.49	GO:0010157	response to chlorate
0.49	GO:0071397	cellular response to cholesterol

0.86	GO:0008158	hedgehog receptor activity
0.66	GO:0005119	smoothened binding
0.66	GO:0097108	hedgehog family protein binding
0.48	GO:0005113	patched binding
0.47	GO:0015485	cholesterol binding
0.46	GO:0030332	cyclin binding
0.46	GO:0008201	heparin binding
0.44	GO:0032403	protein complex binding
0.34	GO:0016779	nucleotidyltransferase activity
0.33	GO:0008270	zinc ion binding

0.47	GO:0005901	caveola
0.46	GO:0030496	midbody
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005929	cilium
0.43	GO:0005794	Golgi apparatus
0.39	GO:0044294	dendritic growth cone
0.38	GO:0044295	axonal growth cone
0.37	GO:0014069	postsynaptic density
0.34	GO:0005634	nucleus
0.34	GO:0030666	endocytic vesicle membrane

0.34

GO:0016779

sp|Q9Y6C7|L3R2A_HUMAN
Putative uncharacterized protein encoded by LINC00312
Search

sp|Q9Y6C9|MTCH2_HUMAN
Mitochondrial carrier homolog 2
Search

MTCH2

0.83	Mitochondrial carrier like protein 2

0.53	GO:0070585	protein localization to mitochondrion
0.48	GO:0043065	positive regulation of apoptotic process
0.44	GO:0045444	fat cell differentiation
0.44	GO:0001889	liver development
0.43	GO:0048565	digestive tract development
0.41	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.40	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.40	GO:0010917	negative regulation of mitochondrial membrane potential
0.40	GO:0035701	hematopoietic stem cell migration
0.40	GO:0061484	hematopoietic stem cell homeostasis

0.34	GO:0004181	metallocarboxypeptidase activity
0.33	GO:0008270	zinc ion binding
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005739	mitochondrion
0.39	GO:0070062	extracellular exosome
0.38	GO:0031968	organelle outer membrane
0.37	GO:0019866	organelle inner membrane
0.35	GO:0005634	nucleus
0.32	GO:0005885	Arp2/3 protein complex
0.30	GO:0016021	integral component of membrane

0.34

EC:3.4.17

GO:0004181

sp|Q9Y6D0|SELK_HUMAN
Selenoprotein K
Search

SELENOK

0.97	Selenoprotein K

0.62	GO:0018345	protein palmitoylation
0.61	GO:0045728	respiratory burst after phagocytosis
0.59	GO:0010742	macrophage derived foam cell differentiation
0.58	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.58	GO:0090197	positive regulation of chemokine secretion
0.58	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.57	GO:2000778	positive regulation of interleukin-6 secretion
0.57	GO:2000406	positive regulation of T cell migration
0.57	GO:0006816	calcium ion transport
0.57	GO:0002230	positive regulation of defense response to virus by host

0.51

GO:0042802

identical protein binding

0.55	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005794	Golgi apparatus
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y6D5|BIG2_HUMAN
Brefeldin A-inhibited guanine nucleotide-exchange protein 2
Search

ARFGEF2

0.83	ADP ribosylation factor guanine nucleotide exchange factor 2

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.48	GO:0001881	receptor recycling
0.47	GO:0032760	positive regulation of tumor necrosis factor production
0.47	GO:0007032	endosome organization
0.46	GO:0006893	Golgi to plasma membrane transport
0.40	GO:0035556	intracellular signal transduction
0.39	GO:0090284	positive regulation of protein glycosylation in Golgi
0.38	GO:0090303	positive regulation of wound healing
0.37	GO:0007030	Golgi organization

0.81	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.49	GO:0034237	protein kinase A regulatory subunit binding
0.37	GO:0017022	myosin binding
0.36	GO:0008536	Ran GTPase binding
0.32	GO:0005096	GTPase activator activity
0.30	GO:0005102	receptor binding

0.46	GO:0055037	recycling endosome
0.46	GO:0098791	Golgi subcompartment
0.44	GO:0005815	microtubule organizing center
0.43	GO:0098588	bounding membrane of organelle
0.43	GO:0005829	cytosol
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0030532	small nuclear ribonucleoprotein complex
0.36	GO:0005730	nucleolus
0.35	GO:0005654	nucleoplasm
0.33	GO:0016363	nuclear matrix

sp|Q9Y6D6|BIG1_HUMAN
Brefeldin A-inhibited guanine nucleotide-exchange protein 1
Search

ARFGEF1

0.92	ADP ribosylation factor guanine nucleotide exchange factor 1

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.61	GO:0090284	positive regulation of protein glycosylation in Golgi
0.57	GO:0090303	positive regulation of wound healing
0.55	GO:0007030	Golgi organization
0.54	GO:0030837	negative regulation of actin filament polymerization
0.52	GO:2000114	regulation of establishment of cell polarity
0.43	GO:0016192	vesicle-mediated transport
0.40	GO:0051897	positive regulation of protein kinase B signaling
0.39	GO:0031175	neuron projection development

0.81	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.58	GO:0034237	protein kinase A regulatory subunit binding
0.55	GO:0017022	myosin binding
0.36	GO:0005096	GTPase activator activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0030532	small nuclear ribonucleoprotein complex
0.52	GO:0098791	Golgi subcompartment
0.50	GO:0005730	nucleolus
0.49	GO:0098588	bounding membrane of organelle
0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.40	GO:0016363	nuclear matrix
0.34	GO:0055037	recycling endosome
0.34	GO:0032040	small-subunit processome

sp|Q9Y6D9|MD1L1_HUMAN
Mitotic spindle assembly checkpoint protein MAD1
Search

MAD1L1

0.93	Mitotic spindle assembly checkpoint protein MAD1

0.80	GO:0007094	mitotic spindle assembly checkpoint
0.61	GO:0090235	regulation of metaphase plate congression
0.59	GO:0042130	negative regulation of T cell proliferation
0.58	GO:0048538	thymus development
0.51	GO:0051315	attachment of mitotic spindle microtubules to kinetochore
0.37	GO:0051301	cell division
0.36	GO:0007062	sister chromatid cohesion
0.36	GO:0032259	methylation
0.35	GO:0009451	RNA modification
0.33	GO:0044260	cellular macromolecule metabolic process

0.60	GO:0043515	kinetochore binding
0.53	GO:0042802	identical protein binding
0.36	GO:0008168	methyltransferase activity

0.59	GO:0097431	mitotic spindle pole
0.56	GO:0000776	kinetochore
0.54	GO:0005643	nuclear pore
0.40	GO:0005737	cytoplasm
0.39	GO:0000779	condensed chromosome, centromeric region
0.38	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

0.36

GO:0008168

sp|Q9Y6E0|STK24_HUMAN
Serine/threonine-protein kinase 24
Search

STK24

0.94	Serine/threonine-protein kinase 24

0.60	GO:0006468	protein phosphorylation
0.56	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.55	GO:0048679	regulation of axon regeneration
0.55	GO:0097194	execution phase of apoptosis
0.53	GO:0042542	response to hydrogen peroxide
0.53	GO:0030336	negative regulation of cell migration
0.51	GO:0009267	cellular response to starvation
0.47	GO:0000185	activation of MAPKKK activity
0.47	GO:0031098	stress-activated protein kinase signaling cascade
0.45	GO:0048812	neuron projection morphogenesis

0.61	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0045296	cadherin binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0046872	metal ion binding

0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.36	GO:0005794	Golgi apparatus
0.34	GO:0005654	nucleoplasm
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment

sp|Q9Y6E2|BZW2_HUMAN
Basic leucine zipper and W2 domain-containing protein 2
Search

BZW2

0.96	Basic leucine zipper and W2 domain-containing protein 2

0.48	GO:0007399	nervous system development
0.47	GO:0030154	cell differentiation
0.36	GO:0097659	nucleic acid-templated transcription
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.79

GO:0045296

cadherin binding

0.48	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q9Y6E7|SIR4_HUMAN
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial
Search

SIRT4

0.52	NAD-dependent protein deacylase

0.73	GO:0006471	protein ADP-ribosylation
0.69	GO:0006476	protein deacetylation
0.60	GO:0046322	negative regulation of fatty acid oxidation
0.59	GO:1904182	regulation of pyruvate dehydrogenase activity
0.58	GO:0046676	negative regulation of insulin secretion
0.57	GO:0046889	positive regulation of lipid biosynthetic process
0.55	GO:0000820	regulation of glutamine family amino acid metabolic process
0.51	GO:0018205	peptidyl-lysine modification
0.50	GO:0006541	glutamine metabolic process
0.49	GO:0072350	tricarboxylic acid metabolic process

0.77	GO:0070403	NAD+ binding
0.70	GO:0034979	NAD-dependent protein deacetylase activity
0.62	GO:0061690	lipoamidase activity
0.62	GO:0047708	biotinidase activity
0.62	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.56	GO:0008270	zinc ion binding
0.40	GO:0004407	histone deacetylase activity
0.34	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.67	GO:0005759	mitochondrial matrix
0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.33	GO:0005681	spliceosomal complex

0.62

EC:3.5.1.12

GO:0047708

sp|Q9Y6F1|PARP3_HUMAN
Poly [ADP-ribose] polymerase 3
Search

PARP3

0.58	Poly [ADP-ribose] polymerase

0.84	GO:0006471	protein ADP-ribosylation
0.75	GO:0006302	double-strand break repair
0.64	GO:0051106	positive regulation of DNA ligation
0.64	GO:1990166	protein localization to site of double-strand break
0.60	GO:0060236	regulation of mitotic spindle organization
0.56	GO:0000723	telomere maintenance
0.50	GO:0006273	lagging strand elongation
0.49	GO:0051103	DNA ligation involved in DNA repair
0.47	GO:0090299	regulation of neural crest formation
0.45	GO:0071696	ectodermal placode development

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.48	GO:0003910	DNA ligase (ATP) activity
0.34	GO:1990404	protein ADP-ribosylase activity
0.33	GO:0047485	protein N-terminus binding
0.33	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.33	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0051287	NAD binding
0.33	GO:0019901	protein kinase binding
0.33	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding

0.59	GO:0035861	site of double-strand break
0.37	GO:0005737	cytoplasm
0.35	GO:0005815	microtubule organizing center
0.35	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.32	GO:0032993	protein-DNA complex
0.32	GO:0012505	endomembrane system
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0031967	organelle envelope

0.82

EC:2.4.2.30

GO:0003950

sp|Q9Y6F6|MRVI1_HUMAN
Protein MRVI1
Search

MRVI1

0.97	Murine retrovirus integration site 1 homolog

0.38	GO:0060087	relaxation of vascular smooth muscle
0.38	GO:0019934	cGMP-mediated signaling

0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q9Y6F7|CDY2_HUMAN
Testis-specific chromodomain protein Y 2
Search

CDYL

0.92	Chromodomain protein Y-linked

0.50	GO:0120093	regulation of peptidyl-lysine crotonylation
0.45	GO:0060816	random inactivation of X chromosome
0.44	GO:0007283	spermatogenesis
0.43	GO:0031400	negative regulation of protein modification process
0.42	GO:1903507	negative regulation of nucleic acid-templated transcription
0.42	GO:0007281	germ cell development
0.41	GO:0016573	histone acetylation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0006355	regulation of transcription, DNA-templated
0.35	GO:0030041	actin filament polymerization

0.49	GO:0120092	crotonyl-CoA hydratase activity
0.47	GO:0140034	methylation-dependent protein binding
0.45	GO:0042393	histone binding
0.45	GO:0003714	transcription corepressor activity
0.44	GO:0030674	protein binding, bridging
0.41	GO:0004402	histone acetyltransferase activity
0.41	GO:0003682	chromatin binding

0.58	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0005694	chromosome
0.38	GO:0044446	intracellular organelle part
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0004402

sp|Q9Y6F8|CDY1_HUMAN
Testis-specific chromodomain protein Y 1
Search

CDYL

0.92	Chromodomain protein Y-linked

0.50	GO:0120093	regulation of peptidyl-lysine crotonylation
0.45	GO:0060816	random inactivation of X chromosome
0.44	GO:0007283	spermatogenesis
0.43	GO:0031400	negative regulation of protein modification process
0.42	GO:1903507	negative regulation of nucleic acid-templated transcription
0.42	GO:0007281	germ cell development
0.41	GO:0016573	histone acetylation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0006355	regulation of transcription, DNA-templated
0.35	GO:0030041	actin filament polymerization

0.50	GO:0120092	crotonyl-CoA hydratase activity
0.47	GO:0140034	methylation-dependent protein binding
0.45	GO:0042393	histone binding
0.45	GO:0003714	transcription corepressor activity
0.44	GO:0030674	protein binding, bridging
0.41	GO:0004402	histone acetyltransferase activity
0.41	GO:0003682	chromatin binding

0.58	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0005694	chromosome
0.38	GO:0044446	intracellular organelle part
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0004402

sp|Q9Y6F9|WNT6_HUMAN
Protein Wnt-6
Search

sp|Q9Y6G1|TM14A_HUMAN
Transmembrane protein 14A
Search

TMEM14A

0.63	Transmembrane protein 14C isoform A

0.62	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.40	GO:0070453	regulation of heme biosynthetic process
0.39	GO:0030218	erythrocyte differentiation
0.35	GO:0006915	apoptotic process
0.33	GO:0006629	lipid metabolic process

0.34	GO:0005515	protein binding
0.33	GO:0008081	phosphoric diester hydrolase activity
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0003676	nucleic acid binding

0.52	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1.4

GO:0008081

sp|Q9Y6G3|RM42_HUMAN
39S ribosomal protein L42, mitochondrial
Search

MRPL42

0.95	Mitochondrial ribosomal protein L42

0.38	GO:0070126	mitochondrial translational termination
0.38	GO:0070125	mitochondrial translational elongation
0.35	GO:0046426	negative regulation of JAK-STAT cascade
0.34	GO:0001558	regulation of cell growth
0.34	GO:0016567	protein ubiquitination
0.33	GO:0006886	intracellular protein transport
0.33	GO:0035556	intracellular signal transduction

0.35	GO:0003723	RNA binding
0.35	GO:0008269	JAK pathway signal transduction adaptor activity
0.35	GO:0005159	insulin-like growth factor receptor binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0008536	Ran GTPase binding

0.60	GO:0005840	ribosome
0.56	GO:0005759	mitochondrial matrix
0.45	GO:0005886	plasma membrane
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y6G5|COMDA_HUMAN
COMM domain-containing protein 10
Search

COMMD10

0.97	COMM domain-containing protein 10

0.53	GO:0097659	nucleic acid-templated transcription
0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0006471	protein ADP-ribosylation
0.51	GO:0010468	regulation of gene expression
0.49	GO:0010467	gene expression

0.51	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.49	GO:0005515	protein binding

0.55	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.51

EC:2.4.2.30

GO:0003950

sp|Q9Y6G9|DC1L1_HUMAN
Cytoplasmic dynein 1 light intermediate chain 1
Search

DYNC1LI1

0.96	Cytoplasmic dynein light-intermediate chain 1

0.72	GO:0007018	microtubule-based movement
0.60	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.47	GO:0000226	microtubule cytoskeleton organization
0.43	GO:0051642	centrosome localization
0.40	GO:0009794	regulation of mitotic cell cycle, embryonic
0.39	GO:0070507	regulation of microtubule cytoskeleton organization
0.39	GO:0090235	regulation of metaphase plate congression
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

0.73	GO:0003777	microtubule motor activity
0.61	GO:0045504	dynein heavy chain binding
0.58	GO:0019003	GDP binding
0.35	GO:0005525	GTP binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0003723	RNA binding

0.81	GO:0005868	cytoplasmic dynein complex
0.56	GO:0005813	centrosome
0.55	GO:0000922	spindle pole
0.54	GO:0000776	kinetochore
0.38	GO:0000779	condensed chromosome, centromeric region
0.38	GO:0005874	microtubule
0.36	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0005770	late endosome
0.35	GO:0005764	lysosome
0.34	GO:0005829	cytosol

sp|Q9Y6H1|CHCH2_HUMAN
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2
Search

CHCHD2

0.90	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

0.73	GO:1900037	regulation of cellular response to hypoxia
0.67	GO:0045944	positive regulation of transcription by RNA polymerase II
0.61	GO:0007005	mitochondrion organization
0.47	GO:0005978	glycogen biosynthetic process
0.43	GO:0006468	protein phosphorylation
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0048193	Golgi vesicle transport

0.61	GO:0008134	transcription factor binding
0.59	GO:0043565	sequence-specific DNA binding
0.52	GO:0004689	phosphorylase kinase activity
0.48	GO:0005516	calmodulin binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005758	mitochondrial intermembrane space
0.58	GO:0005634	nucleus
0.51	GO:0005964	phosphorylase kinase complex
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:2.7.11.19

GO:0004689

sp|Q9Y6H3|ATP23_HUMAN
Mitochondrial inner membrane protease ATP23 homolog
Search

ATP23

0.71	Mitochondrial inner membrane protease ATP23

0.60	GO:0006508	proteolysis
0.35	GO:0006303	double-strand break repair via nonhomologous end joining
0.33	GO:0006468	protein phosphorylation
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.36	GO:0004677	DNA-dependent protein kinase activity
0.33	GO:0003735	structural constituent of ribosome

0.51	GO:0030054	cell junction
0.48	GO:0005829	cytosol
0.44	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0005886	plasma membrane
0.38	GO:0019866	organelle inner membrane
0.36	GO:0070419	nonhomologous end joining complex
0.33	GO:0005840	ribosome

0.70

GO:0004222

sp|Q9Y6H5|SNCAP_HUMAN
Synphilin-1
Search

SNCAIP

0.96	Synuclein, alpha interacting protein (Synphilin)

0.85	GO:0090083	regulation of inclusion body assembly
0.85	GO:0042417	dopamine metabolic process
0.84	GO:0046928	regulation of neurotransmitter secretion
0.75	GO:0008219	cell death
0.36	GO:0044267	cellular protein metabolic process
0.35	GO:0006897	endocytosis
0.35	GO:0006886	intracellular protein transport

0.77	GO:0031625	ubiquitin protein ligase binding
0.71	GO:0042802	identical protein binding
0.35	GO:0035091	phosphatidylinositol binding

0.77	GO:0036464	cytoplasmic ribonucleoprotein granule
0.68	GO:0005654	nucleoplasm
0.43	GO:0042734	presynaptic membrane
0.42	GO:0008021	synaptic vesicle
0.42	GO:0043025	neuronal cell body
0.39	GO:0005829	cytosol
0.36	GO:0030904	retromer complex
0.30	GO:0016021	integral component of membrane

sp|Q9Y6H6|KCNE3_HUMAN
Potassium voltage-gated channel subfamily E member 3
Search

KCNE3

0.97	Potassium voltage-gated channel subfamily E regulatory subunit 3

0.78	GO:1903765	negative regulation of potassium ion export across plasma membrane
0.78	GO:1903946	negative regulation of ventricular cardiac muscle cell action potential
0.78	GO:1905032	negative regulation of membrane repolarization during cardiac muscle cell action potential
0.76	GO:1905024	regulation of membrane repolarization during ventricular cardiac muscle cell action potential
0.75	GO:1902260	negative regulation of delayed rectifier potassium channel activity
0.73	GO:0071805	potassium ion transmembrane transport
0.72	GO:0086091	regulation of heart rate by cardiac conduction
0.45	GO:1901387	positive regulation of voltage-gated calcium channel activity

0.78	GO:0005249	voltage-gated potassium channel activity
0.72	GO:0015459	potassium channel regulator activity
0.43	GO:0044325	ion channel binding

0.73	GO:0032809	neuronal cell body membrane
0.71	GO:0043204	perikaryon
0.67	GO:0030425	dendrite
0.67	GO:0045121	membrane raft
0.65	GO:0008076	voltage-gated potassium channel complex
0.60	GO:0031982	vesicle
0.44	GO:0005737	cytoplasm

sp|Q9Y6H8|CXA3_HUMAN
Gap junction alpha-3 protein
Search

GJA3

0.62	Gap junction protein (Fragment)

0.73	GO:0007601	visual perception
0.60	GO:0007154	cell communication
0.52	GO:0055085	transmembrane transport
0.46	GO:0048050	post-embryonic eye morphogenesis
0.46	GO:0003161	cardiac conduction system development
0.45	GO:0055008	cardiac muscle tissue morphogenesis
0.44	GO:0008016	regulation of heart contraction
0.44	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.34	GO:0023052	signaling
0.34	GO:0042542	response to hydrogen peroxide

0.82	GO:0005243	gap junction channel activity
0.33	GO:0042802	identical protein binding

0.84	GO:0005922	connexin complex
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0045121	membrane raft

sp|Q9Y6I3|EPN1_HUMAN
Epsin-1
Search

EPN1

0.76	Phosphatidylinositol-binding clathrin assembly protein

0.70	GO:1903671	negative regulation of sprouting angiogenesis
0.62	GO:0006897	endocytosis
0.58	GO:0007565	female pregnancy
0.56	GO:0001701	in utero embryonic development
0.56	GO:0007219	Notch signaling pathway
0.55	GO:0048568	embryonic organ development
0.50	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.49	GO:0045747	positive regulation of Notch signaling pathway
0.35	GO:0006397	mRNA processing
0.35	GO:1905445	positive regulation of clathrin coat assembly

0.48	GO:0045296	cadherin binding
0.36	GO:0008289	lipid binding
0.35	GO:0035615	clathrin adaptor activity
0.34	GO:0044325	ion channel binding
0.34	GO:0003723	RNA binding
0.34	GO:0008134	transcription factor binding

0.73	GO:0030128	clathrin coat of endocytic vesicle
0.53	GO:0005829	cytosol
0.40	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0005905	clathrin-coated pit
0.36	GO:0098890	extrinsic component of postsynaptic membrane
0.35	GO:0098888	extrinsic component of presynaptic membrane
0.35	GO:0043195	terminal bouton
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

sp|Q9Y6I4|UBP3_HUMAN
Ubiquitin carboxyl-terminal hydrolase 3
Search

USP3

0.58	Ubiquitin carboxyl-terminal hydrolase 3

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.52	GO:0031647	regulation of protein stability
0.51	GO:0016570	histone modification
0.50	GO:0000278	mitotic cell cycle
0.46	GO:0006281	DNA repair
0.39	GO:0006355	regulation of transcription, DNA-templated
0.38	GO:1903507	negative regulation of nucleic acid-templated transcription
0.37	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.37	GO:0010629	negative regulation of gene expression

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.61	GO:0008270	zinc ion binding
0.52	GO:0042393	histone binding
0.40	GO:1990841	promoter-specific chromatin binding
0.39	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity

0.57	GO:0090543	Flemming body
0.52	GO:0036464	cytoplasmic ribonucleoprotein granule
0.50	GO:0000790	nuclear chromatin
0.48	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.76

GO:0036459

sp|Q9Y6I7|WSB1_HUMAN
WD repeat and SOCS box-containing protein 1
Search

WSB1

0.96	WD repeat and SOCS box-containing protein 1

0.65	GO:0016567	protein ubiquitination
0.59	GO:0035556	intracellular signal transduction
0.35	GO:0043687	post-translational protein modification

0.38	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding

0.44

GO:0005622

intracellular

0.38

GO:0004842

sp|Q9Y6I8|PXMP4_HUMAN
Peroxisomal membrane protein 4
Search

PXMP4

0.95	Peroxisomal membrane protein 4

0.33	GO:0006351	transcription, DNA-templated
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.66	GO:0031903	microbody membrane
0.66	GO:0044439	peroxisomal part
0.34	GO:0005667	transcription factor complex
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q9Y6I9|TX264_HUMAN
Testis-expressed protein 264
Search

TEX264

0.97	Testis-expressed protein 264

0.54

GO:0002576

platelet degranulation

0.43

GO:0005515

protein binding

0.57	GO:0070062	extracellular exosome
0.55	GO:0031093	platelet alpha granule lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y6J0|CABIN_HUMAN
Calcineurin-binding protein cabin-1
Search

CABIN1

0.87	Calcineurin binding protein 1

0.85	GO:0006336	DNA replication-independent nucleosome assembly
0.35	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.33	GO:0007165	signal transduction

0.52	GO:0031491	nucleosome binding
0.35	GO:0004864	protein phosphatase inhibitor activity

0.66	GO:0016235	aggresome
0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol

sp|Q9Y6J3|SMA5O_HUMAN
SMAD5 antisense gene protein 1
Search

0.37	SMAD5 antisense gene protein 1

0.61

GO:0007165

signal transduction

sp|Q9Y6J6|KCNE2_HUMAN
Potassium voltage-gated channel subfamily E member 2
Search

sp|Q9Y6J8|STYL1_HUMAN
Serine/threonine/tyrosine-interacting-like protein 1
Search

STYXL1

0.97	Serine/threonine/tyrosine interacting like 1

0.72	GO:0006470	protein dephosphorylation
0.35	GO:0035556	intracellular signal transduction

0.78

GO:0008138

protein tyrosine/serine/threonine phosphatase activity

0.33	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0008138

sp|Q9Y6J9|TAF6L_HUMAN
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L
Search

TAF6L

0.96	PCAF-associated factor 65-alpha

0.80	GO:0051090	regulation of DNA binding transcription factor activity
0.68	GO:0006352	DNA-templated transcription, initiation
0.49	GO:0043966	histone H3 acetylation
0.38	GO:0006338	chromatin remodeling
0.37	GO:0006357	regulation of transcription by RNA polymerase II

0.73	GO:0046982	protein heterodimerization activity
0.47	GO:0004402	histone acetyltransferase activity
0.47	GO:0003713	transcription coactivator activity
0.37	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0003676	nucleic acid binding

0.82	GO:0046695	SLIK (SAGA-like) complex
0.80	GO:0000124	SAGA complex
0.80	GO:0005669	transcription factor TFIID complex
0.50	GO:0030914	STAGA complex
0.41	GO:0070062	extracellular exosome
0.39	GO:0000118	histone deacetylase complex
0.30	GO:0016020	membrane

0.47

GO:0004402

sp|Q9Y6K0|CEPT1_HUMAN
Choline/ethanolaminephosphotransferase 1
Search

CEPT1

0.92	Choline/ethanolamine phosphotransferase 1

0.68	GO:0008654	phospholipid biosynthetic process
0.57	GO:0046470	phosphatidylcholine metabolic process
0.52	GO:0045017	glycerolipid biosynthetic process
0.42	GO:1901566	organonitrogen compound biosynthetic process
0.40	GO:0046337	phosphatidylethanolamine metabolic process
0.36	GO:0046469	platelet activating factor metabolic process
0.34	GO:0010469	regulation of receptor activity

0.71	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.35	GO:0046872	metal ion binding
0.34	GO:0005179	hormone activity

0.51	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031965	nuclear membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.71

EC:2.7.8

GO:0016780

sp|Q9Y6K1|DNM3A_HUMAN
DNA (cytosine-5)-methyltransferase 3A
Search

DNMT3A

0.87	DNA methyltransferase 3 alpha

0.74	GO:0006306	DNA methylation
0.64	GO:1901538	changes to DNA methylation involved in embryo development
0.63	GO:0006346	methylation-dependent chromatin silencing
0.62	GO:0006349	regulation of gene expression by genetic imprinting
0.60	GO:0071230	cellular response to amino acid stimulus
0.57	GO:0007283	spermatogenesis
0.56	GO:0022412	cellular process involved in reproduction in multicellular organism
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II

0.76	GO:0009008	DNA-methyltransferase activity
0.56	GO:0003682	chromatin binding
0.55	GO:0042802	identical protein binding
0.52	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.44	GO:0003677	DNA binding

0.62	GO:0001741	XY body
0.62	GO:0000791	euchromatin
0.61	GO:0016363	nuclear matrix
0.59	GO:0005720	nuclear heterochromatin
0.55	GO:0000775	chromosome, centromeric region
0.53	GO:0005654	nucleoplasm
0.41	GO:0005737	cytoplasm

0.76

GO:0009008

sp|Q9Y6K5|OAS3_HUMAN
2'-5'-oligoadenylate synthase 3
Search

0.10	2'-5'-oligoadenylate synthase 3

0.78	GO:0051607	defense response to virus
0.73	GO:0006955	immune response
0.55	GO:0045071	negative regulation of viral genome replication
0.50	GO:0060700	regulation of ribonuclease activity
0.50	GO:0035457	cellular response to interferon-alpha
0.47	GO:0042593	glucose homeostasis
0.44	GO:0006164	purine nucleotide biosynthetic process
0.44	GO:0051259	protein oligomerization
0.44	GO:0006006	glucose metabolic process
0.42	GO:0019221	cytokine-mediated signaling pathway

0.77	GO:0003725	double-stranded RNA binding
0.62	GO:0016779	nucleotidyltransferase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008270	zinc ion binding
0.38	GO:0005515	protein binding
0.38	GO:0003735	structural constituent of ribosome

0.47	GO:0005829	cytosol
0.46	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.42	GO:0005576	extracellular region
0.37	GO:0005840	ribosome
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.35	GO:0005886	plasma membrane

0.62

GO:0016779

sp|Q9Y6K8|KAD5_HUMAN
Adenylate kinase isoenzyme 5
Search

AK5

0.59	Adenylate kinase isoenzyme 5

0.62	GO:0046939	nucleotide phosphorylation
0.61	GO:0006172	ADP biosynthetic process
0.58	GO:0009142	nucleoside triphosphate biosynthetic process
0.55	GO:0046033	AMP metabolic process
0.54	GO:0046034	ATP metabolic process
0.45	GO:0007050	cell cycle arrest
0.41	GO:0033993	response to lipid
0.40	GO:1901700	response to oxygen-containing compound
0.40	GO:0060271	cilium assembly
0.40	GO:0002237	response to molecule of bacterial origin

0.72	GO:0019205	nucleobase-containing compound kinase activity
0.65	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008373	sialyltransferase activity
0.36	GO:0030695	GTPase regulator activity

0.48	GO:0044430	cytoskeletal part
0.48	GO:0005829	cytosol
0.46	GO:0015630	microtubule cytoskeleton
0.45	GO:0036126	sperm flagellum
0.42	GO:0044441	ciliary part
0.40	GO:0099512	supramolecular fiber
0.37	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0043005	neuron projection

0.65

EC:2.7.4

GO:0016776

sp|Q9Y6K9|NEMO_HUMAN
NF-kappa-B essential modulator
Search

IKBKG

0.92	Inhibitor of kappa light polypeptide gene enhancer in B-cells kinase gamma

0.63	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.59	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.57	GO:0051650	establishment of vesicle localization
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0006974	cellular response to DNA damage stimulus
0.47	GO:0016310	phosphorylation
0.41	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.36	GO:0036211	protein modification process
0.35	GO:0044267	cellular protein metabolic process

0.85	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.65	GO:1990450	linear polyubiquitin binding
0.56	GO:0031625	ubiquitin protein ligase binding
0.55	GO:0019904	protein domain specific binding
0.54	GO:0042803	protein homodimerization activity
0.54	GO:0046982	protein heterodimerization activity
0.48	GO:0016301	kinase activity
0.40	GO:0042975	peroxisome proliferator activated receptor binding

0.65	GO:0008385	IkappaB kinase complex
0.57	GO:0072686	mitotic spindle
0.56	GO:0000922	spindle pole
0.55	GO:0000151	ubiquitin ligase complex
0.48	GO:0005634	nucleus

sp|Q9Y6L6|SO1B1_HUMAN
Solute carrier organic anion transporter family member 1B1
Search

0.62	Solute carrier organic anion transporter family member

0.59	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.47	GO:0015850	organic hydroxy compound transport
0.46	GO:0006869	lipid transport
0.44	GO:0015849	organic acid transport
0.40	GO:0070327	thyroid hormone transport
0.38	GO:1905431	microcystin transport
0.37	GO:0051384	response to glucocorticoid
0.36	GO:0001889	liver development
0.36	GO:0032496	response to lipopolysaccharide

0.56

GO:0005215

transporter activity

0.55	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9Y6L7|TLL2_HUMAN
Tolloid-like protein 2
Search

0.64	Metalloendopeptidase

0.61	GO:0006508	proteolysis
0.50	GO:0061036	positive regulation of cartilage development
0.48	GO:0048632	negative regulation of skeletal muscle tissue growth
0.37	GO:0035124	embryonic caudal fin morphogenesis
0.37	GO:0048264	determination of ventral identity
0.36	GO:0036342	post-anal tail morphogenesis
0.36	GO:0007585	respiratory gaseous exchange
0.36	GO:0001885	endothelial cell development
0.36	GO:0030513	positive regulation of BMP signaling pathway
0.36	GO:0035162	embryonic hemopoiesis

0.70	GO:0004222	metalloendopeptidase activity
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding
0.45	GO:0042802	identical protein binding

0.45	GO:0005615	extracellular space
0.35	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

sp|Q9Y6M0|TEST_HUMAN
Testisin
Search

0.92	Eosinophil serine protease-1

0.61	GO:0006508	proteolysis
0.59	GO:0007283	spermatogenesis
0.45	GO:0007596	blood coagulation
0.43	GO:0051919	positive regulation of fibrinolysis
0.39	GO:0006898	receptor-mediated endocytosis
0.39	GO:0051604	protein maturation
0.39	GO:0006030	chitin metabolic process
0.38	GO:1904627	response to phorbol 13-acetate 12-myristate
0.38	GO:0006501	C-terminal protein lipidation
0.36	GO:0065009	regulation of molecular function

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0005044	scavenger receptor activity
0.39	GO:0017080	sodium channel regulator activity
0.39	GO:0008061	chitin binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.33	GO:0070009	serine-type aminopeptidase activity
0.33	GO:0008201	heparin binding
0.32	GO:0003723	RNA binding

0.45	GO:0005576	extracellular region
0.43	GO:0031225	anchored component of membrane
0.40	GO:0019897	extrinsic component of plasma membrane
0.39	GO:0031226	intrinsic component of plasma membrane
0.35	GO:0043226	organelle
0.34	GO:0005622	intracellular
0.33	GO:0012505	endomembrane system
0.33	GO:0097180	serine protease inhibitor complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|Q9Y6M1|IF2B2_HUMAN
Insulin-like growth factor 2 mRNA-binding protein 2
Search

IGF2BP2

0.91	Insulin like growth factor 2 mRNA binding protein 2

0.38	GO:0051028	mRNA transport
0.37	GO:0006417	regulation of translation
0.36	GO:0042035	regulation of cytokine biosynthetic process
0.35	GO:0043488	regulation of mRNA stability
0.35	GO:0034249	negative regulation of cellular amide metabolic process
0.34	GO:0009653	anatomical structure morphogenesis
0.34	GO:0032269	negative regulation of cellular protein metabolic process
0.34	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.34	GO:0010629	negative regulation of gene expression

0.73	GO:0003729	mRNA binding
0.35	GO:0045182	translation regulator activity
0.33	GO:0005515	protein binding

0.38	GO:0005829	cytosol
0.37	GO:0005856	cytoskeleton
0.36	GO:0005634	nucleus

sp|Q9Y6M4|KC1G3_HUMAN
Casein kinase I isoform gamma-3
Search

CSNK1G3

0.80	Casein kinase I

0.63	GO:0006468	protein phosphorylation
0.54	GO:0018209	peptidyl-serine modification
0.45	GO:0016055	Wnt signaling pathway
0.42	GO:0006897	endocytosis
0.42	GO:0008360	regulation of cell shape

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0051219	phosphoprotein binding
0.35	GO:0042277	peptide binding
0.34	GO:0000287	magnesium ion binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004674

sp|Q9Y6M5|ZNT1_HUMAN
Zinc transporter 1
Search

SLC30A1

0.76	Zinc transporter 1

0.64	GO:0071584	negative regulation of zinc ion transmembrane import
0.60	GO:0090281	negative regulation of calcium ion import
0.59	GO:0006882	cellular zinc ion homeostasis
0.58	GO:0006829	zinc II ion transport
0.56	GO:0098655	cation transmembrane transport
0.56	GO:0001701	in utero embryonic development
0.56	GO:0006874	cellular calcium ion homeostasis
0.52	GO:0061088	regulation of sequestering of zinc ion
0.51	GO:0010043	response to zinc ion
0.50	GO:0065009	regulation of molecular function

0.63	GO:0019855	calcium channel inhibitor activity
0.56	GO:0008324	cation transmembrane transporter activity
0.42	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.34	GO:0005515	protein binding
0.33	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving

0.56	GO:0031965	nuclear membrane
0.53	GO:0005794	Golgi apparatus
0.53	GO:0005783	endoplasmic reticulum
0.45	GO:0005886	plasma membrane
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0098588	bounding membrane of organelle
0.32	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.33

EC:3.4.23

GO:0042500

sp|Q9Y6M7|S4A7_HUMAN
Sodium bicarbonate cotransporter 3
Search

SLC4A7

0.64	Anion exchange protein (Fragment)

0.69	GO:0098656	anion transmembrane transport
0.68	GO:0015698	inorganic anion transport
0.47	GO:0015701	bicarbonate transport
0.46	GO:0051453	regulation of intracellular pH
0.44	GO:0035725	sodium ion transmembrane transport
0.44	GO:0060117	auditory receptor cell development
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.82	GO:0005452	inorganic anion exchanger activity
0.48	GO:0008510	sodium:bicarbonate symporter activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005887	integral component of plasma membrane
0.34	GO:0032420	stereocilium
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0016324	apical plasma membrane
0.34	GO:0045202	synapse
0.33	GO:0031410	cytoplasmic vesicle
0.33	GO:0005634	nucleus

sp|Q9Y6M9|NDUB9_HUMAN
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
Search

NDUFB9

0.92	NADH dehydrogenase ubiquinone 1 beta subcomplex subunit 9

0.75	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.57	GO:0032981	mitochondrial respiratory chain complex I assembly
0.35	GO:0007605	sensory perception of sound

0.34	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0005515	protein binding

0.81	GO:0005747	mitochondrial respiratory chain complex I
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.34

EC:1.6.5.3

GO:0008137

sp|Q9Y6N1|COX11_HUMAN
Cytochrome c oxidase assembly protein COX11, mitochondrial
Search

COX11

0.95	Cytochrome c oxidase assembly protein COX11, mitochondrial

0.60	GO:1903300	negative regulation of hexokinase activity
0.59	GO:0033131	regulation of glucokinase activity
0.51	GO:0055065	metal ion homeostasis
0.36	GO:0007585	respiratory gaseous exchange
0.35	GO:0008535	respiratory chain complex IV assembly
0.34	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0022900	electron transport chain
0.32	GO:0006413	translational initiation

0.72	GO:0005507	copper ion binding
0.35	GO:0005515	protein binding
0.34	GO:0015002	heme-copper terminal oxidase activity
0.34	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0003743	translation initiation factor activity

0.45	GO:0005739	mitochondrion
0.44	GO:0043234	protein complex
0.36	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.9.3

GO:0016676

sp|Q9Y6N3|CLCA3_HUMAN
Calcium-activated chloride channel regulator family member 3
Search

0.92	Calcium-activated chloride channel regulator family member 3

0.75	GO:1902476	chloride transmembrane transport
0.39	GO:0043276	anoikis
0.39	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.37	GO:0006508	proteolysis
0.37	GO:0006816	calcium ion transport
0.35	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0007155	cell adhesion
0.34	GO:0098662	inorganic cation transmembrane transport

0.85	GO:0061778	intracellular chloride channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.44	GO:0022834	ligand-gated channel activity
0.38	GO:0008237	metallopeptidase activity
0.35	GO:0005262	calcium channel activity
0.35	GO:0004175	endopeptidase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0022832	voltage-gated channel activity

0.48	GO:0005887	integral component of plasma membrane
0.45	GO:0031965	nuclear membrane
0.44	GO:0030054	cell junction
0.42	GO:0005829	cytosol
0.38	GO:0098590	plasma membrane region
0.37	GO:0045177	apical part of cell
0.37	GO:0005902	microvillus
0.37	GO:0031982	vesicle
0.37	GO:0005576	extracellular region
0.36	GO:0045178	basal part of cell

sp|Q9Y6N5|SQRD_HUMAN
Sulfide:quinone oxidoreductase, mitochondrial
Search

SQRDL

0.59	Sulfide:quinone oxidoreductase, mitochondrial

0.52	GO:0055114	oxidation-reduction process
0.37	GO:0070813	hydrogen sulfide metabolic process

0.53	GO:0016491	oxidoreductase activity
0.35	GO:0048038	quinone binding

0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

0.53

GO:0016491

sp|Q9Y6N6|LAMC3_HUMAN
Laminin subunit gamma-3
Search

LAMC1

0.79	Laminin subunit gamma 3

0.81	GO:0031581	hemidesmosome assembly
0.81	GO:0022617	extracellular matrix disassembly
0.79	GO:0034446	substrate adhesion-dependent cell spreading
0.71	GO:0016477	cell migration
0.63	GO:0006461	protein complex assembly
0.54	GO:0022008	neurogenesis
0.53	GO:0001654	eye development
0.52	GO:0007601	visual perception
0.52	GO:0007417	central nervous system development
0.50	GO:0007634	optokinetic behavior

0.74	GO:0005201	extracellular matrix structural constituent
0.48	GO:0043208	glycosphingolipid binding
0.37	GO:0004871	signal transducer activity
0.37	GO:0005515	protein binding

0.79	GO:0005604	basement membrane
0.45	GO:0005615	extracellular space
0.44	GO:1903561	extracellular vesicle
0.42	GO:0043234	protein complex
0.41	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|Q9Y6N7|ROBO1_HUMAN
Roundabout homolog 1
Search

ROBO1

0.97	Roundabout guidance receptor 1

0.85	GO:0035385	Roundabout signaling pathway
0.81	GO:0007411	axon guidance
0.80	GO:0007507	heart development
0.57	GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration
0.57	GO:0050925	negative regulation of negative chemotaxis
0.56	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.56	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.56	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway
0.55	GO:0002042	cell migration involved in sprouting angiogenesis
0.54	GO:0035025	positive regulation of Rho protein signal transduction

0.55	GO:0030275	LRR domain binding
0.48	GO:0042802	identical protein binding
0.39	GO:0008046	axon guidance receptor activity

0.49	GO:0009986	cell surface
0.42	GO:0005886	plasma membrane
0.38	GO:0030424	axon
0.38	GO:0005737	cytoplasm
0.37	GO:0031252	cell leading edge
0.36	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

sp|Q9Y6N8|CAD10_HUMAN
Cadherin-10
Search

CDH10

0.96	Transmembrane glycoprotein cadherin-10

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.49	GO:0007219	Notch signaling pathway
0.36	GO:0034332	adherens junction organization

0.70	GO:0005509	calcium ion binding
0.34	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q9Y6N9|USH1C_HUMAN
Harmonin
Search

USH1C

0.95	USH1 protein network component harmonin

0.81	GO:0007605	sensory perception of sound
0.61	GO:1904106	protein localization to microvillus
0.60	GO:1904970	brush border assembly
0.58	GO:0050957	equilibrioception
0.57	GO:0045494	photoreceptor cell maintenance
0.56	GO:0000086	G2/M transition of mitotic cell cycle
0.53	GO:0050953	sensory perception of light stimulus
0.49	GO:0043623	cellular protein complex assembly
0.44	GO:0060122	inner ear receptor cell stereocilium organization
0.43	GO:0032532	regulation of microvillus length

0.78	GO:0051015	actin filament binding
0.56	GO:0030507	spectrin binding
0.39	GO:0008281	sulfonylurea receptor activity
0.38	GO:0032029	myosin tail binding
0.36	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0015272	ATP-activated inward rectifier potassium channel activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0051087	chaperone binding

0.57	GO:0005902	microvillus
0.56	GO:0005903	brush border
0.54	GO:0045177	apical part of cell
0.49	GO:0005829	cytosol
0.41	GO:0001917	photoreceptor inner segment
0.40	GO:0032420	stereocilium
0.40	GO:0001750	photoreceptor outer segment
0.39	GO:0045202	synapse
0.36	GO:0005856	cytoskeleton
0.35	GO:0005886	plasma membrane

sp|Q9Y6P5|SESN1_HUMAN
Sestrin-1
Search

SESN1

0.97	Sestrin-1 isoform B

0.85	GO:1901031	regulation of response to reactive oxygen species
0.58	GO:1904262	negative regulation of TORC1 signaling
0.57	GO:0034198	cellular response to amino acid starvation
0.56	GO:0042149	cellular response to glucose starvation
0.51	GO:0072593	reactive oxygen species metabolic process
0.49	GO:0098869	cellular oxidant detoxification
0.44	GO:0007368	determination of left/right symmetry
0.41	GO:0071230	cellular response to amino acid stimulus
0.39	GO:0030308	negative regulation of cell growth
0.39	GO:0051896	regulation of protein kinase B signaling

0.60	GO:0070728	leucine binding
0.38	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor
0.38	GO:0016209	antioxidant activity
0.36	GO:0005092	GDP-dissociation inhibitor activity
0.35	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.58	GO:0061700	GATOR2 complex
0.47	GO:0043233	organelle lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.37	GO:0031932	TORC2 complex
0.36	GO:1902554	serine/threonine protein kinase complex
0.36	GO:0031588	nucleotide-activated protein kinase complex
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.38

EC:1.11

GO:0016684

sp|Q9Y6Q1|CAN6_HUMAN
Calpain-6
Search

CAPN6

0.93	Calpamodulin

0.69	GO:0051493	regulation of cytoskeleton organization
0.61	GO:0006508	proteolysis
0.57	GO:0001578	microtubule bundle formation
0.35	GO:0007165	signal transduction
0.34	GO:0007608	sensory perception of smell
0.34	GO:0043066	negative regulation of apoptotic process

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.52	GO:0008017	microtubule binding
0.39	GO:0005509	calcium ion binding
0.33	GO:0004871	signal transducer activity

0.56	GO:0005876	spindle microtubule
0.55	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005829	cytosol
0.36	GO:0009986	cell surface

sp|Q9Y6Q2|STON1_HUMAN
Stonin-1
Search

STON1

0.96	STON1-GTF2A1L readthrough transcript

0.80	GO:0030100	regulation of endocytosis
0.71	GO:0006897	endocytosis
0.57	GO:0006367	transcription initiation from RNA polymerase II promoter
0.49	GO:0036465	synaptic vesicle recycling
0.42	GO:0002244	hematopoietic progenitor cell differentiation
0.41	GO:0006886	intracellular protein transport
0.40	GO:0099003	vesicle-mediated transport in synapse
0.35	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:0007268	chemical synaptic transmission
0.32	GO:0061024	membrane organization

0.38	GO:0003713	transcription coactivator activity
0.33	GO:0005515	protein binding

0.59	GO:0005672	transcription factor TFIIA complex
0.47	GO:0098793	presynapse
0.44	GO:0030131	clathrin adaptor complex
0.41	GO:0070382	exocytic vesicle
0.41	GO:0030136	clathrin-coated vesicle
0.38	GO:0005730	nucleolus
0.38	GO:0005829	cytosol
0.34	GO:0043005	neuron projection
0.34	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y6Q3|ZFP37_HUMAN
Zinc finger protein 37 homolog
Search

ZFP37

0.76	Zinc finger protein 37

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.41	GO:0006351	transcription, DNA-templated
0.37	GO:0030154	cell differentiation
0.36	GO:0007283	spermatogenesis
0.36	GO:0007010	cytoskeleton organization
0.36	GO:0022412	cellular process involved in reproduction in multicellular organism
0.36	GO:0022604	regulation of cell morphogenesis
0.36	GO:0008283	cell proliferation

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part

sp|Q9Y6Q5|AP1M2_HUMAN
AP-1 complex subunit mu-2
Search

AP1M2

0.94	AP-1 complex subunit mu-2

0.68	GO:0006886	intracellular protein transport
0.67	GO:0016192	vesicle-mediated transport
0.49	GO:0007420	brain development
0.45	GO:0048565	digestive tract development
0.45	GO:0001822	kidney development
0.43	GO:0009887	animal organ morphogenesis
0.37	GO:0035646	endosome to melanosome transport
0.37	GO:0032438	melanosome organization
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0051650	establishment of vesicle localization

0.34

GO:0030276

clathrin binding

0.77	GO:0030131	clathrin adaptor complex
0.42	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0030665	clathrin-coated vesicle membrane
0.37	GO:0012505	endomembrane system
0.35	GO:0031984	organelle subcompartment
0.34	GO:0030120	vesicle coat
0.34	GO:0030660	Golgi-associated vesicle membrane
0.34	GO:0005829	cytosol

sp|Q9Y6Q6|TNR11_HUMAN
Tumor necrosis factor receptor superfamily member 11A
Search

TNFRSF11A

0.96	Tumor necrosis factor receptor superfamily member 11A

0.78	GO:0060086	circadian temperature homeostasis
0.78	GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion
0.78	GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
0.74	GO:0048535	lymph node development
0.73	GO:0030316	osteoclast differentiation
0.72	GO:0061377	mammary gland lobule development
0.72	GO:0043507	positive regulation of JUN kinase activity
0.72	GO:0032496	response to lipopolysaccharide
0.71	GO:0070555	response to interleukin-1
0.70	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.77	GO:0005031	tumor necrosis factor-activated receptor activity
0.70	GO:0019955	cytokine binding
0.36	GO:0046872	metal ion binding

0.69	GO:0009897	external side of plasma membrane
0.59	GO:0005829	cytosol
0.48	GO:0005887	integral component of plasma membrane

sp|Q9Y6Q9|NCOA3_HUMAN
Nuclear receptor coactivator 3
Search

NCOA3

0.96	Nuclear receptor coactivator 3

0.65	GO:0045618	positive regulation of keratinocyte differentiation
0.64	GO:0071392	cellular response to estradiol stimulus
0.58	GO:0016573	histone acetylation
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0010468	regulation of gene expression
0.56	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:0030522	intracellular receptor signaling pathway
0.40	GO:1902459	positive regulation of stem cell population maintenance

0.85	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.82	GO:0035257	nuclear hormone receptor binding
0.67	GO:0046983	protein dimerization activity
0.63	GO:0097718	disordered domain specific binding
0.62	GO:0047485	protein N-terminus binding
0.59	GO:0004402	histone acetyltransferase activity
0.39	GO:0000993	RNA polymerase II core binding
0.36	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.54	GO:0000785	chromatin
0.52	GO:0005829	cytosol
0.52	GO:0031974	membrane-enclosed lumen
0.47	GO:0043234	protein complex
0.37	GO:0070062	extracellular exosome
0.33	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.59

GO:0004402

sp|Q9Y6R0|NUMBL_HUMAN
Numb-like protein
Search

NUMBL

0.95	Numb homolog (Drosophila)

0.82	GO:0021849	neuroblast division in subventricular zone
0.78	GO:0021670	lateral ventricle development
0.74	GO:0034332	adherens junction organization
0.71	GO:0050769	positive regulation of neurogenesis
0.70	GO:0007409	axonogenesis
0.69	GO:0019221	cytokine-mediated signaling pathway
0.65	GO:0060319	primitive erythrocyte differentiation
0.55	GO:0045746	negative regulation of Notch signaling pathway
0.54	GO:0007368	determination of left/right symmetry
0.49	GO:0019538	protein metabolic process

0.43

GO:0005515

protein binding

0.51	GO:0016323	basolateral plasma membrane
0.48	GO:0005737	cytoplasm
0.38	GO:0045177	apical part of cell
0.38	GO:0019897	extrinsic component of plasma membrane
0.37	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0005925	focal adhesion
0.35	GO:0005634	nucleus

sp|Q9Y6R1|S4A4_HUMAN
Electrogenic sodium bicarbonate cotransporter 1
Search

SLC4A4

0.62	Anion exchange protein (Fragment)

0.69	GO:0098656	anion transmembrane transport
0.69	GO:0015698	inorganic anion transport
0.59	GO:0015701	bicarbonate transport
0.54	GO:0035725	sodium ion transmembrane transport
0.45	GO:0051453	regulation of intracellular pH

0.83	GO:0005452	inorganic anion exchanger activity
0.61	GO:0008510	sodium:bicarbonate symporter activity

0.52	GO:0016323	basolateral plasma membrane
0.40	GO:0005887	integral component of plasma membrane

sp|Q9Y6R4|M3K4_HUMAN
Mitogen-activated protein kinase kinase kinase 4
Search

MAP3K4

0.96	Mitogen-activated protein kinase kinase kinase 4

0.67	GO:0019100	male germ-line sex determination
0.66	GO:0060718	chorionic trophoblast cell differentiation
0.66	GO:0010225	response to UV-C
0.65	GO:1904355	positive regulation of telomere capping
0.65	GO:1900745	positive regulation of p38MAPK cascade
0.64	GO:0051973	positive regulation of telomerase activity
0.64	GO:0032212	positive regulation of telomere maintenance via telomerase
0.63	GO:0043507	positive regulation of JUN kinase activity
0.63	GO:0006468	protein phosphorylation
0.62	GO:0000186	activation of MAPKK activity

0.63	GO:0004672	protein kinase activity
0.59	GO:0005057	signal transducer activity, downstream of receptor
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.42	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9Y6R6|Z780B_HUMAN
Zinc finger protein 780B
Search

0.68	Zinc finger protein 626

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0006351	transcription, DNA-templated
0.38	GO:0034249	negative regulation of cellular amide metabolic process
0.38	GO:0032269	negative regulation of cellular protein metabolic process
0.37	GO:1902679	negative regulation of RNA biosynthetic process

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.47	GO:0003700	DNA binding transcription factor activity
0.40	GO:0030371	translation repressor activity
0.36	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044422	organelle part

sp|Q9Y6R7|FCGBP_HUMAN
IgGFc-binding protein
Search

0.10	IgGFc-binding protein

0.37	GO:0006364	rRNA processing
0.36	GO:0008033	tRNA processing
0.36	GO:0032259	methylation

0.38	GO:0005509	calcium ion binding
0.36	GO:0008168	methyltransferase activity
0.35	GO:0003723	RNA binding
0.30	GO:0005515	protein binding

0.65	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008168

sp|Q9Y6R9|CCD61_HUMAN
Coiled-coil domain-containing protein 61
Search

CCDC61

0.96	Coiled-coil domain-containing protein 61

0.37

GO:0006470

protein dephosphorylation

0.38	GO:0004722	protein serine/threonine phosphatase activity
0.37	GO:0030145	manganese ion binding
0.36	GO:0000287	magnesium ion binding

0.77

GO:0005813

centrosome

sp|Q9Y6S9|RPKL1_HUMAN
Ribosomal protein S6 kinase-like 1
Search

RPS6KL1

0.95	Ribosomal protein S6 kinase polypeptide 1

0.63	GO:0006468	protein phosphorylation
0.43	GO:0007165	signal transduction
0.35	GO:0010469	regulation of receptor activity
0.34	GO:1905303	positive regulation of macropinocytosis
0.34	GO:0044351	macropinocytosis
0.34	GO:0043327	chemotaxis to cAMP
0.34	GO:0050765	negative regulation of phagocytosis
0.34	GO:0090382	phagosome maturation
0.34	GO:0006298	mismatch repair
0.34	GO:0046580	negative regulation of Ras protein signal transduction

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0035091	phosphatidylinositol binding
0.35	GO:0008083	growth factor activity
0.32	GO:0019887	protein kinase regulator activity
0.32	GO:0060089	molecular transducer activity
0.32	GO:0003676	nucleic acid binding

0.39	GO:0005840	ribosome
0.33	GO:0005938	cell cortex
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane

sp|Q9Y6T7|DGKB_HUMAN
Diacylglycerol kinase beta
Search

DGKB

0.49	Diacylglycerol kinase beta

0.79	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.48	GO:0030258	lipid modification
0.48	GO:0046486	glycerolipid metabolic process
0.35	GO:0030168	platelet activation

0.79	GO:0004143	diacylglycerol kinase activity
0.74	GO:0003951	NAD+ kinase activity
0.69	GO:0005509	calcium ion binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.41	GO:0005886	plasma membrane
0.34	GO:0043227	membrane-bounded organelle

0.79	EC:2.7.1.107	GO:0004143
0.74	KEGG:R00104	GO:0003951

sp|Q9Y6U3|ADSV_HUMAN
Adseverin
Search

SCIN

0.97

Adseverin

0.83	GO:0051014	actin filament severing
0.60	GO:0051693	actin filament capping
0.59	GO:0030838	positive regulation of actin filament polymerization
0.57	GO:0045654	positive regulation of megakaryocyte differentiation
0.56	GO:0042989	sequestering of actin monomers
0.53	GO:0051125	regulation of actin nucleation
0.52	GO:0008285	negative regulation of cell proliferation
0.51	GO:0043065	positive regulation of apoptotic process
0.48	GO:0007015	actin filament organization
0.39	GO:0032330	regulation of chondrocyte differentiation

0.78	GO:0051015	actin filament binding
0.69	GO:0005509	calcium ion binding
0.38	GO:0001786	phosphatidylserine binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0005545	1-phosphatidylinositol binding

0.51	GO:0005903	brush border
0.41	GO:0005886	plasma membrane
0.39	GO:0002102	podosome
0.37	GO:0030054	cell junction
0.36	GO:0042995	cell projection
0.36	GO:0005938	cell cortex
0.35	GO:0070062	extracellular exosome

sp|Q9Y6U7|RN215_HUMAN
RING finger protein 215
Search

RNF215

0.70	Galactose-3-O-sulfotransferase 1

0.35	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0016567	protein ubiquitination
0.33	GO:0045859	regulation of protein kinase activity
0.32	GO:0007165	signal transduction

0.38	GO:0046872	metal ion binding
0.37	GO:0016874	ligase activity
0.36	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.34	GO:0031588	nucleotide-activated protein kinase complex
0.33	GO:0000324	fungal-type vacuole
0.33	GO:0005774	vacuolar membrane
0.33	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:6	GO:0016874
0.35	KEGG:R03876	GO:0004842

sp|Q9Y6V0|PCLO_HUMAN
Protein piccolo
Search

PCLO

0.96	Piccolo presynaptic cytomatrix protein a

0.84	GO:0007416	synapse assembly
0.67	GO:0099526	presynapse to nucleus signaling pathway
0.63	GO:0035418	protein localization to synapse
0.62	GO:0030073	insulin secretion
0.60	GO:0019933	cAMP-mediated signaling
0.59	GO:0017157	regulation of exocytosis
0.53	GO:0007010	cytoskeleton organization
0.45	GO:0016079	synaptic vesicle exocytosis
0.42	GO:0006903	vesicle targeting
0.41	GO:0140029	exocytic process

0.64	GO:0005522	profilin binding
0.48	GO:0046872	metal ion binding
0.44	GO:0005544	calcium-dependent phospholipid binding
0.41	GO:0098882	structural constituent of presynaptic active zone
0.39	GO:0001222	transcription corepressor binding

0.83	GO:0048786	presynaptic active zone
0.60	GO:0014069	postsynaptic density
0.60	GO:0099738	cell cortex region
0.44	GO:0099569	presynaptic cytoskeleton
0.42	GO:0030054	cell junction
0.42	GO:0070062	extracellular exosome
0.42	GO:0030863	cortical cytoskeleton
0.40	GO:0044317	rod spherule
0.40	GO:0044316	cone cell pedicle
0.39	GO:0097470	ribbon synapse

sp|Q9Y6V7|DDX49_HUMAN
Probable ATP-dependent RNA helicase DDX49
Search

DDX49

0.97	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49

0.54

GO:0010501

RNA secondary structure unwinding

0.66	GO:0004386	helicase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008186	RNA-dependent ATPase activity
0.51	GO:0003676	nucleic acid binding
0.44	GO:0140098	catalytic activity, acting on RNA

0.50	GO:0005730	nucleolus
0.39	GO:0005737	cytoplasm

sp|Q9Y6W3|CAN7_HUMAN
Calpain-7
Search

CAPN7

0.92	LOW QUALITY PROTEIN: calpain-7

0.61	GO:0006508	proteolysis
0.55	GO:0010634	positive regulation of epithelial cell migration

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.60	GO:0090541	MIT domain binding
0.33	GO:0005198	structural molecule activity

0.45	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome
0.34	GO:0099512	supramolecular fiber
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part

sp|Q9Y6W5|WASF2_HUMAN
Wiskott-Aldrich syndrome protein family member 2
Search

WASF2

0.97	Wiskott-Aldrich syndrome protein family member 2

0.74	GO:0030036	actin cytoskeleton organization
0.62	GO:0051497	negative regulation of stress fiber assembly
0.62	GO:0010592	positive regulation of lamellipodium assembly
0.62	GO:0072673	lamellipodium morphogenesis
0.61	GO:0035855	megakaryocyte development
0.61	GO:0016601	Rac protein signal transduction
0.60	GO:0030032	lamellipodium assembly
0.58	GO:0030048	actin filament-based movement
0.57	GO:0001667	ameboidal-type cell migration
0.56	GO:0001525	angiogenesis

0.69	GO:0003779	actin binding
0.59	GO:0051018	protein kinase A binding
0.58	GO:0045296	cadherin binding
0.57	GO:0017124	SH3 domain binding
0.54	GO:0032403	protein complex binding
0.34	GO:0004969	histamine receptor activity

0.69	GO:0005856	cytoskeleton
0.61	GO:0031209	SCAR complex
0.59	GO:0030027	lamellipodium
0.57	GO:0001726	ruffle
0.56	GO:0005769	early endosome
0.54	GO:0005911	cell-cell junction
0.41	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q9Y6W6|DUS10_HUMAN
Dual specificity protein phosphatase 10
Search

DUSP10

0.97	Dual specificity protein phosphatase 10

0.84	GO:0000188	inactivation of MAPK activity
0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.62	GO:0043508	negative regulation of JUN kinase activity
0.62	GO:1903753	negative regulation of p38MAPK cascade
0.61	GO:0045591	positive regulation of regulatory T cell differentiation
0.61	GO:1905042	negative regulation of epithelium regeneration
0.60	GO:0035970	peptidyl-threonine dephosphorylation
0.60	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.59	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.58	GO:0090335	regulation of brown fat cell differentiation

0.84	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.73	GO:0004725	protein tyrosine phosphatase activity
0.63	GO:0008330	protein tyrosine/threonine phosphatase activity
0.62	GO:0048273	mitogen-activated protein kinase p38 binding
0.61	GO:0008432	JUN kinase binding

0.55	GO:0016607	nuclear speck
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005829	cytosol

0.84

GO:0017017

sp|Q9Y6W8|ICOS_HUMAN
Inducible T-cell costimulator
Search

ICOS

0.97	Inducible T-cell co-stimulator

0.53	GO:0002517	T cell tolerance induction
0.51	GO:0031295	T cell costimulation
0.47	GO:0098609	cell-cell adhesion
0.40	GO:0051897	positive regulation of protein kinase B signaling
0.38	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0006955	immune response

0.41	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005515	protein binding

0.68	GO:0009897	external side of plasma membrane
0.57	GO:0005887	integral component of plasma membrane
0.37	GO:0005576	extracellular region

0.41	EC:2.7.1.153	GO:0046934
0.41	KEGG:R04545	GO:0046934

sp|Q9Y6X0|SETBP_HUMAN
SET-binding protein
Search

SETBP1

0.93	SET binding protein 1

0.54	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.55	GO:0016604	nuclear body
0.50	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y6X1|SERP1_HUMAN
Stress-associated endoplasmic reticulum protein 1
Search

SERP1

0.84	Stress-associated endoplasmic reticulum protein 1

0.61	GO:0015031	protein transport
0.54	GO:0030968	endoplasmic reticulum unfolded protein response
0.51	GO:0060124	positive regulation of growth hormone secretion
0.49	GO:0046622	positive regulation of organ growth
0.49	GO:0032024	positive regulation of insulin secretion
0.48	GO:0048644	muscle organ morphogenesis
0.48	GO:0010259	multicellular organism aging
0.47	GO:0001501	skeletal system development
0.46	GO:0006486	protein glycosylation
0.46	GO:0009791	post-embryonic development

0.34	GO:0005515	protein binding
0.34	GO:0003735	structural constituent of ribosome

0.70	GO:0005783	endoplasmic reticulum
0.67	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.63	GO:0031984	organelle subcompartment
0.48	GO:0005881	cytoplasmic microtubule
0.34	GO:0005840	ribosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q9Y6X2|PIAS3_HUMAN
E3 SUMO-protein ligase PIAS3
Search

PIAS3

0.92	Protein inhibitor of activated STAT 3

0.76	GO:0016925	protein sumoylation
0.67	GO:0033235	positive regulation of protein sumoylation
0.67	GO:0033234	negative regulation of protein sumoylation
0.48	GO:0060766	negative regulation of androgen receptor signaling pathway
0.47	GO:0045667	regulation of osteoblast differentiation
0.44	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated

0.77	GO:0019789	SUMO transferase activity
0.63	GO:0008270	zinc ion binding
0.62	GO:0008022	protein C-terminus binding
0.58	GO:0019899	enzyme binding
0.44	GO:0061659	ubiquitin-like protein ligase activity
0.43	GO:0008134	transcription factor binding
0.38	GO:0003677	DNA binding

0.51	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.41	GO:0005737	cytoplasm
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q9Y6X3|SCC4_HUMAN
MAU2 chromatid cohesion factor homolog
Search

MAU2

0.95	MAU2 sister chromatid cohesion factor

0.82	GO:0007064	mitotic sister chromatid cohesion
0.60	GO:0034086	maintenance of sister chromatid cohesion
0.60	GO:0071921	cohesin loading
0.36	GO:0051301	cell division
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.56	GO:0047485	protein N-terminus binding
0.43	GO:0003690	double-stranded DNA binding
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0032116	SMC loading complex
0.53	GO:0016604	nuclear body
0.51	GO:0000785	chromatin

sp|Q9Y6X4|F169A_HUMAN
Soluble lamin-associated protein of 75 kDa
Search

FAM169A

0.97	Soluble lamin-associated protein of

0.47

GO:0008080

N-acetyltransferase activity

0.73

GO:0005637

nuclear inner membrane

0.47

EC:2.3.1

GO:0008080

sp|Q9Y6X5|ENPP4_HUMAN
Bis(5'-adenosyl)-triphosphatase ENPP4
Search

ENPP4

0.96	Ectonucleotide pyrophosphatase/phosphodiesterase 4

0.85	GO:0030194	positive regulation of blood coagulation
0.54	GO:0046130	purine ribonucleoside catabolic process
0.41	GO:0007596	blood coagulation
0.36	GO:0043312	neutrophil degranulation
0.32	GO:0007154	cell communication

0.85	GO:0047710	bis(5'-adenosyl)-triphosphatase activity
0.35	GO:0046872	metal ion binding

0.38	GO:0070062	extracellular exosome
0.36	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.85	EC:3.6.1.29	GO:0047710
0.85	KEGG:R00187	GO:0047710

sp|Q9Y6X6|MYO16_HUMAN
Unconventional myosin-XVI
Search

MYO16

0.97	Unconventional myosin-XVI

0.62	GO:0014065	phosphatidylinositol 3-kinase signaling
0.58	GO:0048812	neuron projection morphogenesis
0.54	GO:0007018	microtubule-based movement
0.41	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.41	GO:0021549	cerebellum development
0.40	GO:0008285	negative regulation of cell proliferation
0.34	GO:0016310	phosphorylation

0.71	GO:0003779	actin binding
0.70	GO:0003774	motor activity
0.55	GO:0008017	microtubule binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0032403	protein complex binding
0.36	GO:0019903	protein phosphatase binding
0.34	GO:0016301	kinase activity

0.74	GO:0016459	myosin complex
0.40	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y6X8|ZHX2_HUMAN
Zinc fingers and homeoboxes protein 2
Search

ZHX2

0.96	Zinc fingers and homeoboxes protein 2

0.59	GO:0035019	somatic stem cell population maintenance
0.57	GO:0045665	negative regulation of neuron differentiation
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0006402	mRNA catabolic process
0.36	GO:0006351	transcription, DNA-templated

0.59	GO:0003714	transcription corepressor activity
0.55	GO:0042803	protein homodimerization activity
0.55	GO:0003677	DNA binding
0.55	GO:0046982	protein heterodimerization activity
0.48	GO:0003700	DNA binding transcription factor activity
0.47	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.44	GO:0005886	plasma membrane

sp|Q9Y6X9|MORC2_HUMAN
MORC family CW-type zinc finger protein 2
Search

MORC2

0.97	MORC family CW-type zinc finger protein 2

0.34

GO:0006631

fatty acid metabolic process

0.62

GO:0008270

zinc ion binding

0.48	GO:0005829	cytosol
0.46	GO:0005634	nucleus

sp|Q9Y6Y0|NS1BP_HUMAN
Influenza virus NS1A-binding protein
Search

IVNS1ABP

0.92	Influenza virus NS1A binding protein IV

0.56	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.35	GO:0006383	transcription by RNA polymerase III
0.34	GO:0009615	response to virus
0.34	GO:0008380	RNA splicing
0.33	GO:0016032	viral process

0.33

GO:0005515

protein binding

0.74	GO:0015629	actin cytoskeleton
0.47	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044446	intracellular organelle part

sp|Q9Y6Y1|CMTA1_HUMAN
Calmodulin-binding transcription activator 1
Search

CAMTA1

0.82	Calmodulin-binding transcription activator 1

0.51	GO:0050885	neuromuscular process controlling balance
0.47	GO:0006366	transcription by RNA polymerase II
0.47	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0016192	vesicle-mediated transport

0.53	GO:0003677	DNA binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.45	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q9Y6Y8|S23IP_HUMAN
SEC23-interacting protein
Search

SEC23IP

0.97	Putative phosphatidic acid-preferring phospholipase a1 (Fragment)

0.71	GO:0006888	ER to Golgi vesicle-mediated transport
0.48	GO:0007030	Golgi organization
0.38	GO:0001675	acrosome assembly
0.37	GO:0007338	single fertilization
0.36	GO:0006901	vesicle coating
0.36	GO:0048199	vesicle targeting, to, from or within Golgi
0.35	GO:0048194	Golgi vesicle budding
0.35	GO:0090141	positive regulation of mitochondrial fission
0.35	GO:0019433	triglyceride catabolic process
0.35	GO:0034389	lipid particle organization

0.53	GO:0046872	metal ion binding
0.46	GO:0004620	phospholipase activity
0.35	GO:0004806	triglyceride lipase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.33	GO:0004930	G-protein coupled receptor activity

0.50	GO:0005794	Golgi apparatus
0.47	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.38	GO:0070971	endoplasmic reticulum exit site
0.38	GO:0097038	perinuclear endoplasmic reticulum
0.37	GO:0005801	cis-Golgi network
0.37	GO:0030658	transport vesicle membrane
0.36	GO:0030660	Golgi-associated vesicle membrane
0.36	GO:0030662	coated vesicle membrane
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:0005829	cytosol

0.46

EC:3.1.1

GO:0004620

sp|Q9Y6Y9|LY96_HUMAN
Lymphocyte antigen 96
Search

LY96

0.97	Myeloid differentiation factor 2

0.87	GO:0032497	detection of lipopolysaccharide
0.85	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.85	GO:0031663	lipopolysaccharide-mediated signaling pathway
0.85	GO:0034142	toll-like receptor 4 signaling pathway
0.84	GO:0032760	positive regulation of tumor necrosis factor production
0.50	GO:0006954	inflammatory response
0.49	GO:0045087	innate immune response
0.46	GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway
0.44	GO:0035666	TRIF-dependent toll-like receptor signaling pathway
0.44	GO:0006968	cellular defense response

0.85	GO:0001875	lipopolysaccharide receptor activity
0.43	GO:0015026	coreceptor activity
0.40	GO:0005515	protein binding

0.85	GO:0046696	lipopolysaccharide receptor complex
0.67	GO:0031226	intrinsic component of plasma membrane
0.47	GO:0005615	extracellular space
0.41	GO:0010008	endosome membrane

sp|Q9Y6Z2|CF123_HUMAN
Uncharacterized protein encoded by LINC01558
Search

sp|Q9Y6Z4|KIAS1_HUMAN
Putative uncharacterized protein KIF25-AS1
Search

0.63

GO:0005515

protein binding

sp|Q9Y6Z5|AFAS1_HUMAN
Putative uncharacterized protein AFDN-AS1
Search

sp|Q9Y6Z7|COL10_HUMAN
Collectin-10
Search

COLEC10

0.97	Collectin liver protein 1

0.58	GO:0050918	positive chemotaxis
0.57	GO:1904888	cranial skeletal system development
0.36	GO:0007275	multicellular organism development
0.36	GO:0001867	complement activation, lectin pathway
0.35	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0030154	cell differentiation
0.34	GO:0009888	tissue development
0.34	GO:0001667	ameboidal-type cell migration
0.33	GO:0006508	proteolysis
0.33	GO:0060729	intestinal epithelial structure maintenance

0.59	GO:0042056	chemoattractant activity
0.59	GO:0005537	mannose binding
0.37	GO:0005201	extracellular matrix structural constituent
0.34	GO:0004252	serine-type endopeptidase activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0005262	calcium channel activity
0.32	GO:0018024	histone-lysine N-methyltransferase activity
0.32	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.31	GO:0008270	zinc ion binding

0.75	GO:0005581	collagen trimer
0.52	GO:0005615	extracellular space
0.39	GO:0005737	cytoplasm
0.36	GO:0005604	basement membrane
0.36	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0098645	collagen network
0.32	GO:0019012	virion
0.31	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.34

GO:0004252

tr|R4GMQ9|R4GMQ9_HUMAN
Uncharacterized protein (Fragment)
Search

0.41	GO:0071405	cellular response to methanol
0.39	GO:0045471	response to ethanol
0.39	GO:0010038	response to metal ion
0.38	GO:0007596	blood coagulation
0.38	GO:0009137	purine nucleoside diphosphate catabolic process
0.38	GO:0009191	ribonucleoside diphosphate catabolic process
0.37	GO:0034656	nucleobase-containing small molecule catabolic process
0.36	GO:0010238	response to proline
0.36	GO:0001775	cell activation
0.36	GO:0033602	negative regulation of dopamine secretion

0.51	GO:0016787	hydrolase activity
0.36	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.37	GO:0005605	basal lamina
0.37	GO:0070062	extracellular exosome
0.35	GO:0014069	postsynaptic density
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0008021	synaptic vesicle
0.35	GO:0043025	neuronal cell body
0.35	GO:0097060	synaptic membrane
0.34	GO:0043005	neuron projection
0.34	GO:0009986	cell surface
0.34	GO:0005887	integral component of plasma membrane

0.51