Queries 16001 to 17000

GO:0004674

sp|Q96LA5|FCRL2_HUMAN
Fc receptor-like protein 2
Search

0.94	Fc receptor like 2

0.55	GO:0009967	positive regulation of signal transduction
0.55	GO:0050859	negative regulation of B cell receptor signaling pathway
0.53	GO:0034163	regulation of toll-like receptor 9 signaling pathway
0.53	GO:0002638	negative regulation of immunoglobulin production
0.51	GO:0045577	regulation of B cell differentiation
0.51	GO:0042113	B cell activation
0.51	GO:0030890	positive regulation of B cell proliferation
0.51	GO:0090279	regulation of calcium ion import
0.48	GO:0043408	regulation of MAPK cascade
0.47	GO:0001934	positive regulation of protein phosphorylation

0.53	GO:0005070	SH3/SH2 adaptor activity
0.52	GO:0015026	coreceptor activity
0.50	GO:0019902	phosphatase binding
0.48	GO:0019900	kinase binding
0.45	GO:0005044	scavenger receptor activity
0.35	GO:0042289	MHC class II protein binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0003677	DNA binding

0.62	GO:0009986	cell surface
0.38	GO:0005886	plasma membrane
0.35	GO:0043235	receptor complex
0.34	GO:0070062	extracellular exosome
0.34	GO:0000786	nucleosome
0.34	GO:0098552	side of membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q96LA6|FCRL1_HUMAN
Fc receptor-like protein 1
Search

FCRL1

0.93	Fc receptor like 1

0.58	GO:0042113	B cell activation
0.49	GO:0009967	positive regulation of signal transduction
0.48	GO:0050859	negative regulation of B cell receptor signaling pathway
0.47	GO:0034163	regulation of toll-like receptor 9 signaling pathway
0.47	GO:0002638	negative regulation of immunoglobulin production
0.46	GO:0023052	signaling
0.46	GO:0007154	cell communication
0.46	GO:0045577	regulation of B cell differentiation
0.46	GO:0030890	positive regulation of B cell proliferation
0.46	GO:0090279	regulation of calcium ion import

0.59	GO:0015026	coreceptor activity
0.48	GO:0005044	scavenger receptor activity
0.48	GO:0005070	SH3/SH2 adaptor activity
0.46	GO:0019902	phosphatase binding
0.43	GO:0019900	kinase binding
0.37	GO:0042289	MHC class II protein binding

0.61	GO:0009986	cell surface
0.37	GO:0005886	plasma membrane
0.35	GO:0043235	receptor complex
0.35	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

sp|Q96LA8|ANM6_HUMAN
Protein arginine N-methyltransferase 6
Search

PRMT6

0.96	Arginine N-methyltransferase 8

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.55	GO:0018195	peptidyl-arginine modification
0.53	GO:0090398	cellular senescence
0.51	GO:0016570	histone modification
0.50	GO:0016049	cell growth
0.49	GO:0045892	negative regulation of transcription, DNA-templated
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0006281	DNA repair
0.36	GO:0045652	regulation of megakaryocyte differentiation

0.63	GO:0008168	methyltransferase activity
0.53	GO:0042393	histone binding
0.49	GO:0003682	chromatin binding
0.44	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0016301	kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005730	nucleolus
0.43	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.33	GO:0000785	chromatin

0.63

GO:0008168

sp|Q96LA9|MRGX4_HUMAN
Mas-related G-protein coupled receptor member X4
Search

0.90	MAS-related GPR member X1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:1902349	response to chloroquine
0.52	GO:0002279	mast cell activation involved in immune response
0.52	GO:0002448	mast cell mediated immunity
0.51	GO:0043299	leukocyte degranulation
0.51	GO:0032418	lysosome localization
0.50	GO:0032467	positive regulation of cytokinesis
0.48	GO:0051656	establishment of organelle localization
0.44	GO:0046907	intracellular transport
0.44	GO:0007166	cell surface receptor signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.52	GO:0042923	neuropeptide binding
0.39	GO:0001653	peptide receptor activity

0.52	GO:0042629	mast cell granule
0.39	GO:0005887	integral component of plasma membrane

sp|Q96LB0|MRGX3_HUMAN
Mas-related G-protein coupled receptor member X3
Search

0.90	MAS-related GPR member X1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:1902349	response to chloroquine
0.52	GO:0002279	mast cell activation involved in immune response
0.52	GO:0002448	mast cell mediated immunity
0.51	GO:0043299	leukocyte degranulation
0.50	GO:0032418	lysosome localization
0.50	GO:0032467	positive regulation of cytokinesis
0.47	GO:0051656	establishment of organelle localization
0.44	GO:0007166	cell surface receptor signaling pathway
0.44	GO:0046907	intracellular transport

0.72	GO:0004930	G-protein coupled receptor activity
0.51	GO:0042923	neuropeptide binding
0.39	GO:0001653	peptide receptor activity

0.51	GO:0042629	mast cell granule
0.40	GO:0005887	integral component of plasma membrane

sp|Q96LB1|MRGX2_HUMAN
Mas-related G-protein coupled receptor member X2
Search

0.89	MAS-related GPR member X1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0002279	mast cell activation involved in immune response
0.60	GO:0002448	mast cell mediated immunity
0.59	GO:0043299	leukocyte degranulation
0.59	GO:0032418	lysosome localization
0.58	GO:0032467	positive regulation of cytokinesis
0.54	GO:0051656	establishment of organelle localization
0.50	GO:1902349	response to chloroquine
0.50	GO:0046907	intracellular transport
0.43	GO:0007166	cell surface receptor signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.60	GO:0042923	neuropeptide binding
0.40	GO:0001653	peptide receptor activity

0.60	GO:0042629	mast cell granule
0.41	GO:0005887	integral component of plasma membrane

sp|Q96LB2|MRGX1_HUMAN
Mas-related G-protein coupled receptor member X1
Search

0.90	MAS-related GPR member X1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:1902349	response to chloroquine
0.52	GO:0002279	mast cell activation involved in immune response
0.52	GO:0002448	mast cell mediated immunity
0.51	GO:0043299	leukocyte degranulation
0.51	GO:0032418	lysosome localization
0.50	GO:0032467	positive regulation of cytokinesis
0.48	GO:0051656	establishment of organelle localization
0.45	GO:0007166	cell surface receptor signaling pathway
0.44	GO:0046907	intracellular transport

0.72	GO:0004930	G-protein coupled receptor activity
0.52	GO:0042923	neuropeptide binding
0.39	GO:0001653	peptide receptor activity

0.52	GO:0042629	mast cell granule
0.39	GO:0005887	integral component of plasma membrane

sp|Q96LB3|IFT74_HUMAN
Intraflagellar transport protein 74 homolog
Search

IFT74

0.90	Coiled-coil domain-containing protein 2

0.84	GO:0042073	intraciliary transport
0.79	GO:0060271	cilium assembly
0.62	GO:0003334	keratinocyte development
0.62	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.59	GO:0050680	negative regulation of epithelial cell proliferation
0.58	GO:0007368	determination of left/right symmetry
0.58	GO:0007219	Notch signaling pathway
0.56	GO:0007507	heart development
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0035776	pronephric proximal tubule development

0.84	GO:0048487	beta-tubulin binding
0.55	GO:0003682	chromatin binding
0.35	GO:0140034	methylation-dependent protein binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.35	GO:0042393	histone binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0030992	intraciliary transport particle B
0.76	GO:0005929	cilium
0.57	GO:0005813	centrosome
0.47	GO:0005634	nucleus
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005887	integral component of plasma membrane

0.35

EC:2.7.10.1

GO:0004714

sp|Q96LB4|VATG3_HUMAN
V-type proton ATPase subunit G 3
Search

ATP6V1G3

0.68	V-type proton ATPase subunit G

0.62	GO:0015992	proton transport
0.55	GO:0055085	transmembrane transport
0.48	GO:0036295	cellular response to increased oxygen levels
0.44	GO:0006879	cellular iron ion homeostasis
0.37	GO:0090383	phagosome acidification
0.37	GO:0033572	transferrin transport
0.36	GO:0008286	insulin receptor signaling pathway
0.34	GO:0016241	regulation of macroautophagy
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.58	GO:0051117	ATPase binding
0.49	GO:0022853	active ion transmembrane transporter activity
0.46	GO:0015078	hydrogen ion transmembrane transporter activity

0.82	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.49	GO:0005829	cytosol
0.45	GO:0005765	lysosomal membrane
0.43	GO:0005886	plasma membrane
0.35	GO:0008021	synaptic vesicle
0.35	GO:0070062	extracellular exosome

sp|Q96LB8|PGRP4_HUMAN
Peptidoglycan recognition protein 4
Search

PGLYRP4

0.72	Peptidoglycan recognition protein I-alpha

0.74	GO:0009253	peptidoglycan catabolic process
0.66	GO:0045087	innate immune response
0.47	GO:0019730	antimicrobial humoral response
0.46	GO:0042742	defense response to bacterium
0.44	GO:0051714	positive regulation of cytolysis in other organism
0.43	GO:0046329	negative regulation of JNK cascade
0.43	GO:0016045	detection of bacterium
0.42	GO:0008340	determination of adult lifespan
0.41	GO:0002221	pattern recognition receptor signaling pathway
0.41	GO:0031640	killing of cells of other organism

0.76	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.67	GO:0042834	peptidoglycan binding
0.63	GO:0008270	zinc ion binding
0.44	GO:0016019	peptidoglycan receptor activity
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0008061	chitin binding

0.38	GO:0005887	integral component of plasma membrane
0.37	GO:0043234	protein complex
0.30	GO:0005576	extracellular region
0.30	GO:0005622	intracellular

0.76

EC:3.5.1.28

GO:0008745

sp|Q96LB9|PGRP3_HUMAN
Peptidoglycan recognition protein 3
Search

PGLYRP4

0.72	Peptidoglycan recognition protein I-alpha

0.74	GO:0009253	peptidoglycan catabolic process
0.66	GO:0051714	positive regulation of cytolysis in other organism
0.63	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.63	GO:0016045	detection of bacterium
0.61	GO:0050830	defense response to Gram-positive bacterium
0.60	GO:0002221	pattern recognition receptor signaling pathway
0.58	GO:0031640	killing of cells of other organism
0.43	GO:0045087	innate immune response
0.43	GO:0032827	negative regulation of natural killer cell differentiation involved in immune response
0.42	GO:0044117	growth of symbiont in host

0.76	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.66	GO:0016019	peptidoglycan receptor activity
0.63	GO:0008270	zinc ion binding
0.58	GO:0042834	peptidoglycan binding
0.54	GO:0046982	protein heterodimerization activity

0.46	GO:0043234	protein complex
0.40	GO:0070062	extracellular exosome
0.30	GO:0044464	cell part
0.30	GO:0016020	membrane

0.76

EC:3.5.1.28

GO:0008745

sp|Q96LC7|SIG10_HUMAN
Sialic acid-binding Ig-like lectin 10
Search

0.97	Sialic acid binding Ig like lectin 10

0.58	GO:0106015	negative regulation of inflammatory response to wounding
0.46	GO:0002244	hematopoietic progenitor cell differentiation
0.41	GO:0007155	cell adhesion
0.40	GO:0045087	innate immune response
0.40	GO:0002250	adaptive immune response
0.34	GO:0043312	neutrophil degranulation

0.51	GO:0042169	SH2 domain binding
0.50	GO:0030246	carbohydrate binding
0.50	GO:0019902	phosphatase binding

0.40	GO:0005886	plasma membrane
0.36	GO:0005576	extracellular region
0.34	GO:0101003	ficolin-1-rich granule membrane
0.34	GO:0070821	tertiary granule membrane
0.34	GO:0009986	cell surface
0.34	GO:0098552	side of membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q96LC9|BMF_HUMAN
Bcl-2-modifying factor
Search

BMF

0.97	Bcl-2-modifying factor

0.78	GO:0006915	apoptotic process
0.55	GO:0034644	cellular response to UV
0.52	GO:0043065	positive regulation of apoptotic process
0.51	GO:0010507	negative regulation of autophagy
0.46	GO:0032464	positive regulation of protein homooligomerization
0.45	GO:0090199	regulation of release of cytochrome c from mitochondria
0.45	GO:1904093	negative regulation of autophagic cell death
0.44	GO:0010822	positive regulation of mitochondrion organization
0.42	GO:0009967	positive regulation of signal transduction
0.41	GO:2001234	negative regulation of apoptotic signaling pathway

0.38	GO:0030942	endoplasmic reticulum signal peptide binding
0.37	GO:0005515	protein binding
0.37	GO:0008312	7S RNA binding

0.43	GO:0016459	myosin complex
0.42	GO:0001669	acrosomal vesicle
0.38	GO:0005741	mitochondrial outer membrane
0.38	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.36	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane

sp|Q96LD1|SGCZ_HUMAN
Zeta-sarcoglycan
Search

SGCZ

0.95	Sarcoglycan, delta (dystrophin-associated glycoprotein)

0.51	GO:0060047	heart contraction
0.51	GO:0048738	cardiac muscle tissue development
0.49	GO:0055001	muscle cell development
0.49	GO:0007517	muscle organ development
0.44	GO:0061024	membrane organization
0.38	GO:0048798	swim bladder inflation
0.37	GO:0007525	somatic muscle development
0.37	GO:0007368	determination of left/right symmetry
0.35	GO:0046716	muscle cell cellular homeostasis

0.34

GO:0005515

protein binding

0.85	GO:0016012	sarcoglycan complex
0.53	GO:0042383	sarcolemma
0.37	GO:0005856	cytoskeleton
0.33	GO:0005737	cytoplasm
0.33	GO:0005887	integral component of plasma membrane

sp|Q96LD4|TRI47_HUMAN
Tripartite motif-containing protein 47
Search

TRIM47

0.97	Tripartite motif-containing protein 47

0.35	GO:0010508	positive regulation of autophagy
0.32	GO:0039535	regulation of RIG-I signaling pathway
0.32	GO:0016567	protein ubiquitination

0.61	GO:0008270	zinc ion binding
0.34	GO:0016874	ligase activity
0.32	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.34	EC:6	GO:0016874
0.32	KEGG:R03876	GO:0004842

sp|Q96LD8|SENP8_HUMAN
Sentrin-specific protease 8
Search

SENP8

0.96	Sentrin-specific protease 8

0.61	GO:0006508	proteolysis
0.46	GO:0070647	protein modification by small protein conjugation or removal
0.45	GO:0018205	peptidyl-lysine modification
0.37	GO:0043065	positive regulation of apoptotic process
0.35	GO:0043687	post-translational protein modification
0.33	GO:1902017	regulation of cilium assembly
0.32	GO:0098656	anion transmembrane transport
0.32	GO:0035023	regulation of Rho protein signal transduction
0.32	GO:0065009	regulation of molecular function
0.32	GO:0035556	intracellular signal transduction

0.72	GO:0008234	cysteine-type peptidase activity
0.42	GO:0004175	endopeptidase activity
0.33	GO:0008308	voltage-gated anion channel activity
0.32	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.41	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.33	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

0.72

GO:0008234

sp|Q96LI5|CNO6L_HUMAN
CCR4-NOT transcription complex subunit 6-like
Search

CNOT6L

0.90	CCR4-NOT transcription complex subunit 6 like

0.69	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.51	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.51	GO:0061157	mRNA destabilization
0.50	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.49	GO:0008284	positive regulation of cell proliferation
0.39	GO:0031047	gene silencing by RNA
0.38	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity
0.37	GO:0006397	mRNA processing
0.37	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic
0.37	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay

0.77	GO:0004535	poly(A)-specific ribonuclease activity
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.50	GO:0030014	CCR4-NOT complex
0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus

0.77

EC:3.1.13.4

GO:0004535

sp|Q96LI6|HSFY1_HUMAN
Heat shock transcription factor, Y-linked
Search

0.93	Heat shock transcription factor Y

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.32	GO:0034605	cellular response to heat

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.33	GO:0034708	methyltransferase complex
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q96LI9|CX058_HUMAN
Putative uncharacterized protein CXorf58
Search

sp|Q96LJ7|DHRS1_HUMAN
Dehydrogenase/reductase SDR family member 1
Search

DHRS1

0.96	Dehydrogenase/reductase SDR family member 1 (inferred by orthology to a human protein)

0.39

GO:0055114

oxidation-reduction process

0.39	GO:0016491	oxidoreductase activity
0.37	GO:0005515	protein binding

0.68	GO:0005783	endoplasmic reticulum
0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016491

sp|Q96LJ8|UBX10_HUMAN
UBX domain-containing protein 10
Search

UBXN10

0.97	UBX domain containing 3

0.79	GO:0060271	cilium assembly
0.37	GO:0061371	determination of heart left/right asymmetry

0.38

GO:0005515

protein binding

0.84	GO:0030992	intraciliary transport particle B
0.76	GO:0005929	cilium

sp|Q96LK0|CEP19_HUMAN
Centrosomal protein of 19 kDa
Search

CEP19

0.86	Centrosomal protein of

0.88	GO:0097712	vesicle targeting, trans-Golgi to periciliary membrane compartment
0.85	GO:0034454	microtubule anchoring at centrosome

0.36

GO:0005515

protein binding

0.82	GO:0036064	ciliary basal body
0.82	GO:0005814	centriole
0.79	GO:0000922	spindle pole
0.77	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q96LK8|SPT32_HUMAN
Spermatogenesis-associated protein 32
Search

SPATA32

0.97	Spermatogenesis-associated protein 32

0.80

GO:0007283

spermatogenesis

0.55

GO:0003779

actin binding

0.59

GO:0048471

perinuclear region of cytoplasm

sp|Q96LL3|CP092_HUMAN
Uncharacterized protein C16orf92
Search

sp|Q96LL4|CH048_HUMAN
Uncharacterized protein C8orf48
Search

sp|Q96LL9|DJC30_HUMAN
DnaJ homolog subfamily C member 30
Search

DNAJC30

0.96	DnaJ heat shock protein family (Hsp40) member C30

0.57	GO:0005739	mitochondrion
0.51	GO:0005829	cytosol
0.30	GO:0044425	membrane part

sp|Q96LM1|CL037_HUMAN
Putative uncharacterized protein encoded by LINC00615
Search

sp|Q96LM5|CD045_HUMAN
Uncharacterized protein C4orf45
Search

0.44	Predicted gene, 17359

sp|Q96LM6|TEX37_HUMAN
Testis-expressed sequence 37 protein
Search

0.38

GO:0005515

protein binding

0.49	GO:0005737	cytoplasm
0.42	GO:0005634	nucleus

sp|Q96LM9|CT173_HUMAN
Uncharacterized protein C20orf173
Search

sp|Q96LP2|FA81B_HUMAN
Protein FAM81B
Search

sp|Q96LP6|CL042_HUMAN
Uncharacterized protein C12orf42
Search

sp|Q96LQ0|PPR36_HUMAN
Protein phosphatase 1 regulatory subunit 36
Search

PPP1R36

0.97	Protein phosphatase 1 regulatory subunit 36

0.82	GO:0010923	negative regulation of phosphatase activity
0.45	GO:0035308	negative regulation of protein dephosphorylation
0.44	GO:0043666	regulation of phosphoprotein phosphatase activity

0.83	GO:0019902	phosphatase binding
0.46	GO:0004864	protein phosphatase inhibitor activity

sp|Q96LR1|CRIT1_HUMAN
Putative uncharacterized protein encoded by CRHR1-IT1
Search

sp|Q96LR2|LURA1_HUMAN
Leucine rich adaptor protein 1
Search

LURAP1

0.97	Leucine rich adaptor protein 1

0.84	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.66	GO:0001819	positive regulation of cytokine production
0.43	GO:0031032	actomyosin structure organization
0.42	GO:0016477	cell migration

0.37

GO:0005515

protein binding

0.48	GO:0043231	intracellular membrane-bounded organelle
0.44	GO:0042641	actomyosin
0.43	GO:0005737	cytoplasm

sp|Q96LR4|F19A4_HUMAN
Protein FAM19A4
Search

sp|Q96LR5|UB2E2_HUMAN
Ubiquitin-conjugating enzyme E2 E2
Search

0.76	Ubiquitin-conjugating enzyme E2 E2

0.60	GO:0032020	ISG15-protein conjugation
0.58	GO:0070936	protein K48-linked ubiquitination
0.51	GO:0070979	protein K11-linked ubiquitination
0.51	GO:0070534	protein K63-linked ubiquitination
0.50	GO:0033523	histone H2B ubiquitination
0.49	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.49	GO:0010390	histone monoubiquitination
0.42	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

0.61	GO:0042296	ISG15 transferase activity
0.59	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.46	GO:0000151	ubiquitin ligase complex
0.42	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|Q96LR7|CB050_HUMAN
Uncharacterized protein C2orf50
Search

0.49

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q96LR9|APLD1_HUMAN
Apolipoprotein L domain-containing protein 1
Search

APOLD1

0.97	Apolipoprotein L domain-containing protein 1

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.43	GO:0042118	endothelial cell activation
0.42	GO:0045601	regulation of endothelial cell differentiation
0.41	GO:0001666	response to hypoxia
0.41	GO:0001525	angiogenesis
0.38	GO:0030154	cell differentiation
0.36	GO:0003094	glomerular filtration
0.36	GO:0072010	glomerular epithelium development

0.72	GO:0008289	lipid binding
0.32	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96LS8|CB048_HUMAN
Uncharacterized protein C2orf48
Search

sp|Q96LT4|SAMD8_HUMAN
Sphingomyelin synthase-related protein 1
Search

SAMD8

0.97	Sterile alpha motif domain containing 8

0.60	GO:1905371	ceramide phosphoethanolamine metabolic process
0.58	GO:2000303	regulation of ceramide biosynthetic process
0.58	GO:0046513	ceramide biosynthetic process
0.48	GO:0008654	phospholipid biosynthetic process
0.37	GO:0006684	sphingomyelin metabolic process
0.34	GO:0098656	anion transmembrane transport

0.60	GO:0002950	ceramide phosphoethanolamine synthase activity
0.51	GO:0047493	ceramide cholinephosphotransferase activity
0.50	GO:0033188	sphingomyelin synthase activity
0.35	GO:0008308	voltage-gated anion channel activity

0.53	GO:0030176	integral component of endoplasmic reticulum membrane
0.49	GO:0005829	cytosol
0.47	GO:0030173	integral component of Golgi membrane
0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0005741	mitochondrial outer membrane

0.51	EC:2.7.8.3	GO:0047493
0.51	KEGG:R01891	GO:0047493

sp|Q96LT6|CA074_HUMAN
UPF0739 protein C1orf74
Search

sp|Q96LT7|CI072_HUMAN
Protein C9orf72
Search

0.66	GO:0065009	regulation of molecular function
0.62	GO:0034063	stress granule assembly
0.61	GO:2000785	regulation of autophagosome assembly
0.61	GO:0048675	axon extension
0.61	GO:0016239	positive regulation of macroautophagy
0.60	GO:1903432	regulation of TORC1 signaling
0.57	GO:0006914	autophagy
0.56	GO:0110053	regulation of actin filament organization
0.55	GO:0001933	negative regulation of protein phosphorylation
0.54	GO:0006897	endocytosis

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.58	GO:0017137	Rab GTPase binding

0.63	GO:0044295	axonal growth cone
0.61	GO:0032045	guanyl-nucleotide exchange factor complex
0.61	GO:0005776	autophagosome
0.61	GO:0044304	main axon
0.61	GO:1990316	Atg1/ULK1 kinase complex
0.58	GO:0000932	P-body
0.58	GO:0010494	cytoplasmic stress granule
0.57	GO:0005764	lysosome
0.56	GO:0005768	endosome
0.54	GO:0005615	extracellular space

sp|Q96LT9|RBM40_HUMAN
RNA-binding protein 40
Search

RNPC3

0.96	RNA-binding protein 40

0.49	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0032502	developmental process
0.39	GO:0032501	multicellular organismal process
0.35	GO:0005975	carbohydrate metabolic process
0.33	GO:0022414	reproductive process
0.32	GO:0007165	signal transduction

0.59	GO:0003723	RNA binding
0.39	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.39	GO:0004556	alpha-amylase activity
0.34	GO:0043169	cation binding
0.33	GO:0004871	signal transducer activity
0.32	GO:0003677	DNA binding

0.60	GO:0005689	U12-type spliceosomal complex
0.49	GO:0005654	nucleoplasm
0.34	GO:0017053	transcriptional repressor complex
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:3.2.1.1

GO:0004556

sp|Q96LU5|IMP1L_HUMAN
Mitochondrial inner membrane protease subunit 1
Search

IMMP1L

0.76	Mitochondrial inner membrane protease subunit

0.80	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.48	GO:0033108	mitochondrial respiratory chain complex assembly
0.48	GO:0006465	signal peptide processing

0.67

GO:0008236

serine-type peptidase activity

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.46	GO:0098798	mitochondrial protein complex
0.42	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q96LU7|MRFL_HUMAN
Myelin regulatory factor-like protein
Search

MYRFL

0.88	Myelin regulatory factor

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.36	GO:0032286	central nervous system myelin maintenance
0.36	GO:0031643	positive regulation of myelination
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.32	GO:0004930	G-protein coupled receptor activity

0.34	GO:0005794	Golgi apparatus
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q96LW1|Z354B_HUMAN
Zinc finger protein 354B
Search

0.89	Epididymis luminal protein 104

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.45	GO:1902679	negative regulation of RNA biosynthetic process
0.41	GO:0007576	nucleolar fragmentation
0.40	GO:0051593	response to folic acid
0.39	GO:0007275	multicellular organism development
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:0001666	response to hypoxia
0.36	GO:0009653	anatomical structure morphogenesis

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0003682	chromatin binding
0.44	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0005622	intracellular
0.41	GO:0031974	membrane-enclosed lumen
0.41	GO:0043227	membrane-bounded organelle
0.39	GO:0043228	non-membrane-bounded organelle
0.38	GO:0044422	organelle part
0.34	GO:0012505	endomembrane system
0.33	GO:0031975	envelope
0.33	GO:1990904	ribonucleoprotein complex
0.30	GO:0016020	membrane

sp|Q96LW2|SG494_HUMAN
Uncharacterized serine/threonine-protein kinase SgK494
Search

0.70	Sperm-associated antigen 5

0.63	GO:0006468	protein phosphorylation
0.47	GO:0000160	phosphorelay signal transduction system
0.40	GO:0051988	regulation of attachment of spindle microtubules to kinetochore
0.37	GO:0051294	establishment of spindle orientation
0.37	GO:0007051	spindle organization
0.37	GO:0000070	mitotic sister chromatid segregation
0.36	GO:1905832	positive regulation of spindle assembly
0.36	GO:0090235	regulation of metaphase plate congression
0.36	GO:0071539	protein localization to centrosome
0.36	GO:0051301	cell division

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008017	microtubule binding
0.35	GO:0004332	fructose-bisphosphate aldolase activity

0.38	GO:0005622	intracellular
0.36	GO:0099512	supramolecular fiber
0.34	GO:0043234	protein complex
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part
0.32	GO:0043227	membrane-bounded organelle

0.35

EC:4.1.2.13

GO:0004332

sp|Q96LW4|PRIPO_HUMAN
DNA-directed primase/polymerase protein
Search

PRIMPOL

0.97	Primase and DNA directed polymerase

0.86	GO:0006264	mitochondrial DNA replication
0.81	GO:0031297	replication fork processing
0.81	GO:0019985	translesion synthesis
0.79	GO:0009411	response to UV
0.73	GO:0006269	DNA replication, synthesis of RNA primer
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.75	GO:0003896	DNA primase activity
0.75	GO:0003682	chromatin binding
0.69	GO:0003887	DNA-directed DNA polymerase activity
0.39	GO:0030145	manganese ion binding
0.37	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.73	GO:0005759	mitochondrial matrix
0.60	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.75

GO:0003896

sp|Q96LW7|CAR19_HUMAN
Caspase recruitment domain-containing protein 19
Search

CARD19

0.85	Caspase recruitment domain-containing protein 19

0.54	GO:0042981	regulation of apoptotic process
0.45	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling

0.47

GO:0050700

CARD domain binding

0.58	GO:0005739	mitochondrion
0.45	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.41	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q96LW9|ZSC31_HUMAN
Zinc finger and SCAN domain-containing protein 31
Search

0.92	Zinc finger and SCAN domain-containing protein 31

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.41	GO:0015074	DNA integration

0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.33	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q96LX7|CCD17_HUMAN
Coiled-coil domain-containing protein 17
Search

CCDC17

0.97	Coiled-coil domain-containing protein 17

0.57

GO:0005515

protein binding

sp|Q96LX8|ZN597_HUMAN
Zinc finger protein 597
Search

ZNF597

0.43	Zinc finger protein 597

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.40	GO:0006366	transcription by RNA polymerase II
0.39	GO:1902680	positive regulation of RNA biosynthetic process
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0022604	regulation of cell morphogenesis
0.33	GO:0042476	odontogenesis
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.42	GO:0005622	intracellular
0.38	GO:0031974	membrane-enclosed lumen
0.38	GO:0043227	membrane-bounded organelle
0.37	GO:0043228	non-membrane-bounded organelle
0.37	GO:0044422	organelle part
0.33	GO:0012505	endomembrane system
0.33	GO:0031975	envelope
0.32	GO:1990904	ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q96LY2|CC74B_HUMAN
Coiled-coil domain-containing protein 74B
Search

0.89	Coiled-coil domain-containing protein 74B

sp|Q96LZ2|MAGBA_HUMAN
Melanoma-associated antigen B10
Search

0.96	Melanoma-associated antigen B1

0.40

GO:0007186

G-protein coupled receptor signaling pathway

0.44	GO:0005515	protein binding
0.42	GO:0008528	G-protein coupled peptide receptor activity

0.48	GO:0005737	cytoplasm
0.40	GO:0005654	nucleoplasm
0.30	GO:0044425	membrane part

sp|Q96LZ3|CANB2_HUMAN
Calcineurin subunit B type 2
Search

0.93	Calcineurin B regulatory subunit

0.45	GO:0051531	NFAT protein import into nucleus
0.44	GO:0033173	calcineurin-NFAT signaling cascade
0.44	GO:0060487	lung epithelial cell differentiation
0.43	GO:0001569	branching involved in blood vessel morphogenesis
0.43	GO:0022011	myelination in peripheral nervous system
0.43	GO:0001837	epithelial to mesenchymal transition
0.42	GO:0007507	heart development
0.41	GO:0006529	asparagine biosynthetic process
0.41	GO:0006470	protein dephosphorylation
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II

0.70	GO:0005509	calcium ion binding
0.41	GO:0016018	cyclosporin A binding
0.41	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity
0.41	GO:0004721	phosphoprotein phosphatase activity
0.39	GO:0019904	protein domain specific binding
0.37	GO:0043130	ubiquitin binding
0.35	GO:0019899	enzyme binding
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity
0.34	GO:0005516	calmodulin binding
0.34	GO:0004970	ionotropic glutamate receptor activity

0.43	GO:0042383	sarcolemma
0.41	GO:0005955	calcineurin complex
0.37	GO:0005829	cytosol
0.34	GO:0045211	postsynaptic membrane
0.34	GO:0030054	cell junction
0.33	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.41

EC:6.3.5.4

GO:0004066

sp|Q96LZ7|RMD2_HUMAN
Regulator of microtubule dynamics protein 2
Search

RMDN2

0.96	Regulator of microtubule dynamics protein 2

0.35

GO:0005515

protein binding

0.45	GO:0000922	spindle pole
0.43	GO:0005874	microtubule
0.41	GO:0072686	mitotic spindle
0.39	GO:0005794	Golgi apparatus
0.38	GO:0005829	cytosol
0.36	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|Q96M02|CJ090_HUMAN
Centrosomal protein C10orf90
Search

0.92	Centrosomal protein C10orf90 homolog

0.41	GO:0007095	mitotic G2 DNA damage checkpoint
0.40	GO:0030308	negative regulation of cell growth
0.40	GO:0010212	response to ionizing radiation
0.40	GO:0009411	response to UV
0.40	GO:0050821	protein stabilization

0.48	GO:0051393	alpha-actinin binding
0.47	GO:0042826	histone deacetylase binding

0.78	GO:0005813	centrosome
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.46	GO:0015629	actin cytoskeleton
0.43	GO:0005886	plasma membrane

sp|Q96M11|HYLS1_HUMAN
Hydrolethalus syndrome protein 1
Search

HYLS1

0.95	Hydrolethalus syndrome protein 1

0.52

GO:0060271

cilium assembly

0.30

GO:0005515

protein binding

0.78	GO:0005813	centrosome
0.69	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.56	GO:0005886	plasma membrane
0.53	GO:0005814	centriole
0.51	GO:0005929	cilium

sp|Q96M15|IFAS1_HUMAN
Putative uncharacterized protein IGF2BP2-AS1
Search

sp|Q96M19|CL067_HUMAN
Putative transmembrane protein encoded by LINC00477
Search

0.37	Putative transmembrane protein encoded by LINC00477

0.30

GO:0044425

membrane part

sp|Q96M20|CNBD2_HUMAN
Cyclic nucleotide-binding domain-containing protein 2
Search

CNBD2

0.97	Cyclic nucleotide-binding domain-containing protein 2

0.79	GO:0007283	spermatogenesis
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process
0.33	GO:0036211	protein modification process
0.33	GO:0016310	phosphorylation
0.32	GO:0000160	phosphorelay signal transduction system

0.84	GO:0030552	cAMP binding
0.35	GO:0003735	structural constituent of ribosome
0.33	GO:0004672	protein kinase activity
0.32	GO:0005524	ATP binding

0.68	GO:0005829	cytosol
0.35	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|Q96M27|PRRC1_HUMAN
Protein PRRC1
Search

PRRC1

0.97	Proline rich coiled-coil 1

0.87	GO:0034199	activation of protein kinase A activity
0.86	GO:0001757	somite specification
0.84	GO:0010669	epithelial structure maintenance

0.84

GO:0034237

protein kinase A regulatory subunit binding

0.69	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|Q96M29|TEKT5_HUMAN
Tektin-5
Search

TEKT5

0.94

Tektin-5

0.72	GO:0030317	flagellated sperm motility
0.70	GO:0060271	cilium assembly
0.68	GO:0060294	cilium movement involved in cell motility
0.62	GO:0080154	regulation of fertilization

0.36

GO:0005515

protein binding

0.79	GO:0036126	sperm flagellum
0.54	GO:0002080	acrosomal membrane
0.50	GO:0005634	nucleus
0.38	GO:0015630	microtubule cytoskeleton
0.38	GO:0099513	polymeric cytoskeletal fiber
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q96M32|KAD7_HUMAN
Adenylate kinase 7
Search

AK7

0.96	Adenylate kinase 7

0.66	GO:0046939	nucleotide phosphorylation
0.52	GO:0009132	nucleoside diphosphate metabolic process
0.51	GO:0009142	nucleoside triphosphate biosynthetic process
0.39	GO:0002437	inflammatory response to antigenic stimulus
0.39	GO:0003351	epithelial cilium movement
0.39	GO:0030030	cell projection organization
0.38	GO:0001578	microtubule bundle formation
0.38	GO:0007283	spermatogenesis
0.37	GO:0007420	brain development
0.37	GO:0015949	nucleobase-containing small molecule interconversion

0.76	GO:0004127	cytidylate kinase activity
0.74	GO:0004017	adenylate kinase activity
0.57	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0019206	nucleoside kinase activity

0.37

GO:0005829

cytosol

0.76

EC:2.7.4.14

GO:0004127

sp|Q96M34|CC030_HUMAN
Uncharacterized protein C3orf30
Search

0.47

GO:0030855

epithelial cell differentiation

0.38

GO:0005509

calcium ion binding

0.48	GO:0016324	apical plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96M42|CU129_HUMAN
Putative uncharacterized protein encoded by LINC00479
Search

sp|Q96M43|NBPF4_HUMAN
Neuroblastoma breakpoint family member 4
Search

0.66	Neuroblastoma breakpoint family member 4

0.50	GO:1903955	positive regulation of protein targeting to mitochondrion
0.35	GO:0007616	long-term memory

0.39	GO:0005509	calcium ion binding
0.37	GO:0003723	RNA binding

0.48

GO:0005737

cytoplasm

sp|Q96M53|TBATA_HUMAN
Protein TBATA
Search

TBATA

0.97	Thymus, brain and testes associated

0.46

GO:0048484

enteric nervous system development

0.60	GO:0005634	nucleus
0.39	GO:0005829	cytosol

sp|Q96M60|F227B_HUMAN
Protein FAM227B
Search

sp|Q96M61|MAGBI_HUMAN
Melanoma-associated antigen B18
Search

0.96	LOW QUALITY PROTEIN: melanoma-associated antigen B18

0.40

GO:0005515

protein binding

0.49	GO:0005737	cytoplasm
0.38	GO:0005654	nucleoplasm

sp|Q96M63|CC114_HUMAN
Coiled-coil domain-containing protein 114
Search

CCDC114

0.96	Coiled-coil domain-containing protein 114

0.86	GO:0036158	outer dynein arm assembly
0.83	GO:0003341	cilium movement

0.40

GO:0005515

protein binding

0.86

GO:0036157

outer dynein arm

sp|Q96M66|YP010_HUMAN
Putative uncharacterized protein FLJ32790
Search

sp|Q96M69|LRGUK_HUMAN
Leucine-rich repeat and guanylate kinase domain-containing protein
Search

LRGUK

0.97	Leucine rich repeats and guanylate kinase domain containing

0.67	GO:0035082	axoneme assembly
0.64	GO:0007283	spermatogenesis
0.51	GO:0016310	phosphorylation
0.39	GO:0030154	cell differentiation
0.32	GO:0046710	GDP metabolic process
0.32	GO:0046037	GMP metabolic process

0.53	GO:0016301	kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.32	GO:0016776	phosphotransferase activity, phosphate group as acceptor

0.71	GO:0002177	manchette
0.67	GO:0001669	acrosomal vesicle
0.38	GO:0042995	cell projection

0.32

EC:2.7.4

GO:0016776

sp|Q96M78|FEAS2_HUMAN
Putative uncharacterized protein encoded by FER1L6-AS2
Search

sp|Q96M83|CCDC7_HUMAN
Coiled-coil domain-containing protein 7
Search

0.10	Coiled-coil domain-containing protein 7

0.30

GO:0044425

membrane part

sp|Q96M85|YV008_HUMAN
Putative uncharacterized protein FLJ32756
Search

sp|Q96M86|DNHD1_HUMAN
Dynein heavy chain domain-containing protein 1
Search

DNHD1

0.91	LOW QUALITY PROTEIN: dynein heavy chain domain-containing protein 1

0.74	GO:0007018	microtubule-based movement
0.59	GO:0036159	inner dynein arm assembly
0.33	GO:0015031	protein transport
0.32	GO:0048013	ephrin receptor signaling pathway

0.75	GO:0003777	microtubule motor activity
0.60	GO:0045503	dynein light chain binding
0.60	GO:0051959	dynein light intermediate chain binding
0.59	GO:0045505	dynein intermediate chain binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042623	ATPase activity, coupled
0.32	GO:0046872	metal ion binding
0.32	GO:0046875	ephrin receptor binding

0.76	GO:0030286	dynein complex
0.58	GO:0044447	axoneme part
0.44	GO:0070062	extracellular exosome
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q96M89|CC138_HUMAN
Coiled-coil domain-containing protein 138
Search

CCDC138

0.95	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 138

sp|Q96M91|CFA53_HUMAN
Cilia- and flagella-associated protein 53
Search

CFAP53

0.95	Cilia- and flagella-associated protein 53

0.84	GO:0003341	cilium movement
0.80	GO:0060271	cilium assembly
0.75	GO:0007368	determination of left/right symmetry

0.37

GO:0005515

protein binding

0.53	GO:0005929	cilium
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.37	GO:0044430	cytoskeletal part

sp|Q96M93|ADAD1_HUMAN
Adenosine deaminase domain-containing protein 1
Search

ADAD1

0.97	Adenosine deaminase domain-containing protein 1

0.62	GO:0006396	RNA processing
0.60	GO:0007286	spermatid development
0.38	GO:0007275	multicellular organism development
0.35	GO:0006417	regulation of translation

0.76	GO:0004000	adenosine deaminase activity
0.58	GO:0003723	RNA binding

0.48

GO:0005634

nucleus

0.76

EC:3.5.4.4

GO:0004000

sp|Q96M94|KLH15_HUMAN
Kelch-like protein 15
Search

KLHL15

0.97	LOW QUALITY PROTEIN: kelch-like protein 15

0.71	GO:0016567	protein ubiquitination
0.59	GO:2000042	negative regulation of double-strand break repair via homologous recombination
0.57	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system

0.45	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding

0.81	GO:0031463	Cul3-RING ubiquitin ligase complex
0.45	GO:0005634	nucleus

0.45

GO:0004842

sp|Q96M95|CCD42_HUMAN
Coiled-coil domain-containing protein 42
Search

CCDC42

0.92	Coiled-coil domain-containing protein 42

0.83

GO:0007286

spermatid development

0.39

GO:0005515

protein binding

sp|Q96M96|FGD4_HUMAN
FYVE, RhoGEF and PH domain-containing protein 4
Search

FGD4

0.96	FYVE, RhoGEF and PH domain-containing protein 4

0.76	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.49	GO:0030035	microspike assembly
0.48	GO:0030032	lamellipodium assembly
0.37	GO:0007254	JNK cascade
0.37	GO:0046330	positive regulation of JNK cascade
0.36	GO:0046847	filopodium assembly
0.35	GO:0008360	regulation of cell shape
0.35	GO:0043065	positive regulation of apoptotic process
0.34	GO:0030036	actin cytoskeleton organization

0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.53	GO:0046872	metal ion binding
0.37	GO:0003779	actin binding
0.34	GO:0032403	protein complex binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0030175	filopodium
0.47	GO:0030027	lamellipodium
0.38	GO:0005622	intracellular
0.35	GO:0001726	ruffle
0.35	GO:0043228	non-membrane-bounded organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0043227	membrane-bounded organelle

sp|Q96M98|PACRG_HUMAN
Parkin coregulated gene protein
Search

PACRG

0.92	Parkin coregulated

0.81	GO:0007286	spermatid development
0.76	GO:0060548	negative regulation of cell death
0.52	GO:0034620	cellular response to unfolded protein

0.82	GO:0051879	Hsp90 protein binding
0.82	GO:0030544	Hsp70 protein binding
0.82	GO:0043014	alpha-tubulin binding
0.79	GO:0048487	beta-tubulin binding
0.77	GO:0031625	ubiquitin protein ligase binding
0.75	GO:0001664	G-protein coupled receptor binding
0.72	GO:0051087	chaperone binding
0.69	GO:0003779	actin binding
0.36	GO:0046872	metal ion binding

0.85	GO:0097225	sperm midpiece
0.78	GO:0044297	cell body
0.75	GO:0043005	neuron projection
0.70	GO:0031982	vesicle
0.67	GO:0005829	cytosol
0.59	GO:0005739	mitochondrion
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q96MA1|DMRTB_HUMAN
Doublesex- and mab-3-related transcription factor B1
Search

DMRTB1

0.97	DMRT like family B with proline rich C-terminal 1

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0008406	gonad development
0.34	GO:0030238	male sex determination
0.34	GO:0060179	male mating behavior
0.34	GO:0006915	apoptotic process
0.34	GO:0046546	development of primary male sexual characteristics
0.34	GO:0022602	ovulation cycle process

0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.32	GO:0030545	receptor regulator activity

0.61	GO:0005634	nucleus
0.33	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q96MA6|KAD8_HUMAN
Adenylate kinase 8
Search

AK8

0.96	Adenylate kinase 8

0.64	GO:0046939	nucleotide phosphorylation
0.62	GO:0021591	ventricular system development
0.53	GO:0009132	nucleoside diphosphate metabolic process
0.53	GO:0009142	nucleoside triphosphate biosynthetic process
0.37	GO:0015949	nucleobase-containing small molecule interconversion
0.34	GO:0009165	nucleotide biosynthetic process

0.72	GO:0019205	nucleobase-containing compound kinase activity
0.66	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0004386	helicase activity
0.33	GO:0003723	RNA binding

0.61	GO:0036126	sperm flagellum
0.59	GO:0005930	axoneme
0.39	GO:0005829	cytosol

0.66

EC:2.7.4

GO:0016776

sp|Q96MB7|HARB1_HUMAN
Putative nuclease HARBI1
Search

HARBI1

0.97	Harbinger transposase derived 1

0.43	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0015074	DNA integration

0.43	GO:0004518	nuclease activity
0.39	GO:0046872	metal ion binding
0.35	GO:0043531	ADP binding
0.31	GO:0003676	nucleic acid binding

0.74	GO:0005815	microtubule organizing center
0.67	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.42	GO:0005634	nucleus

0.43

EC:3.1

GO:0004518

sp|Q96MC2|DRC1_HUMAN
Dynein regulatory complex protein 1
Search

DRC1

0.97	Dynein regulatory complex protein 1

0.85	GO:0060285	cilium-dependent cell motility
0.84	GO:0070286	axonemal dynein complex assembly
0.77	GO:0007368	determination of left/right symmetry
0.73	GO:0007507	heart development
0.37	GO:0008654	phospholipid biosynthetic process
0.34	GO:0019538	protein metabolic process
0.33	GO:0006518	peptide metabolic process
0.33	GO:0043604	amide biosynthetic process
0.33	GO:1901566	organonitrogen compound biosynthetic process
0.33	GO:0010467	gene expression

0.38	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0008080	N-acetyltransferase activity
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0046872	metal ion binding

0.52	GO:0005930	axoneme
0.38	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:2.7.8

GO:0016780

sp|Q96MC4|C295L_HUMAN
CEP295 N-terminal-like protein
Search

CEP295NL

0.96	CEP295 N-terminal like

0.39

GO:0005515

protein binding

0.68	GO:0005813	centrosome
0.64	GO:0005929	cilium

sp|Q96MC5|CP045_HUMAN
Uncharacterized protein C16orf45
Search

0.88	GO:0021822	negative regulation of cell motility involved in cerebral cortex radial glia guided migration
0.85	GO:0007026	negative regulation of microtubule depolymerization

0.40

GO:0005515

protein binding

0.70

GO:0015630

microtubule cytoskeleton

sp|Q96MC6|MF14A_HUMAN
Hippocampus abundant transcript 1 protein
Search

MFSD14A

0.91	Hippocampus abundant gene transcript 1

0.55	GO:0055085	transmembrane transport
0.33	GO:0008643	carbohydrate transport
0.33	GO:0005980	glycogen catabolic process
0.33	GO:0015992	proton transport

0.56	GO:0005215	transporter activity
0.33	GO:0004135	amylo-alpha-1,6-glucosidase activity
0.33	GO:0004134	4-alpha-glucanotransferase activity

0.34	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.2.1.33

GO:0004135

sp|Q96MC9|CA147_HUMAN
Uncharacterized protein C1orf147
Search

sp|Q96MD2|CL066_HUMAN
UPF0536 protein C12orf66
Search

C12ORF66

0.97	KICSTOR complex protein C12orf66 homolog

0.82	GO:0061462	protein localization to lysosome
0.82	GO:1904262	negative regulation of TORC1 signaling
0.80	GO:0034198	cellular response to amino acid starvation
0.79	GO:0042149	cellular response to glucose starvation
0.41	GO:0043043	peptide biosynthetic process
0.40	GO:0044267	cellular protein metabolic process
0.38	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process
0.38	GO:0016569	covalent chromatin modification
0.37	GO:1903506	regulation of nucleic acid-templated transcription

0.42	GO:0003735	structural constituent of ribosome
0.39	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0003700	DNA binding transcription factor activity

0.85	GO:0140007	KICSTOR complex
0.71	GO:0005765	lysosomal membrane
0.41	GO:0005840	ribosome
0.40	GO:0005634	nucleus

0.39

EC:2.1.1.43

GO:0018024

sp|Q96MD7|CI085_HUMAN
Uncharacterized protein C9orf85
Search

0.49	GO:0048741	skeletal muscle fiber development
0.47	GO:0035610	protein side chain deglutamylation
0.46	GO:0035335	peptidyl-tyrosine dephosphorylation
0.42	GO:0043401	steroid hormone mediated signaling pathway
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:0010468	regulation of gene expression
0.40	GO:0002098	tRNA wobble uridine modification
0.40	GO:0045454	cell redox homeostasis
0.39	GO:0007601	visual perception

0.46	GO:0004725	protein tyrosine phosphatase activity
0.43	GO:0004181	metallocarboxypeptidase activity
0.42	GO:0008270	zinc ion binding
0.42	GO:0003707	steroid hormone receptor activity
0.41	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.39	GO:0003676	nucleic acid binding
0.38	GO:0003700	DNA binding transcription factor activity
0.35	GO:0016740	transferase activity

0.41	GO:0005634	nucleus
0.41	GO:0033588	Elongator holoenzyme complex
0.38	GO:0005829	cytosol
0.37	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.46

GO:0004725

sp|Q96ME1|FXL18_HUMAN
F-box/LRR-repeat protein 18
Search

FBXL18

0.97	F-box and leucine rich repeat protein 18

0.74	GO:0061056	sclerotome development
0.61	GO:0016567	protein ubiquitination
0.48	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:0043687	post-translational protein modification

0.61	GO:0004842	ubiquitin-protein transferase activity
0.49	GO:0005515	protein binding

0.43	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.61

GO:0004842

sp|Q96ME7|ZN512_HUMAN
Zinc finger protein 512
Search

ZNF512

0.87	Zinc finger protein 512

0.31	GO:0016310	phosphorylation
0.30	GO:0090304	nucleic acid metabolic process
0.30	GO:0010556	regulation of macromolecule biosynthetic process
0.30	GO:0018130	heterocycle biosynthetic process
0.30	GO:1901362	organic cyclic compound biosynthetic process
0.30	GO:0019438	aromatic compound biosynthetic process
0.30	GO:0080090	regulation of primary metabolic process
0.30	GO:0010467	gene expression
0.30	GO:0010468	regulation of gene expression
0.30	GO:0044260	cellular macromolecule metabolic process

0.51	GO:0003676	nucleic acid binding
0.31	GO:0016301	kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0043169	cation binding

0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q96MF0|YO028_HUMAN
Putative uncharacterized protein LOC100506887
Search

sp|Q96MF2|STAC3_HUMAN
SH3 and cysteine-rich domain-containing protein 3
Search

STAC3

0.96	SH3 and cysteine-rich domain-containing protein 3

0.69	GO:1901387	positive regulation of voltage-gated calcium channel activity
0.68	GO:0003009	skeletal muscle contraction
0.65	GO:0007519	skeletal muscle tissue development
0.64	GO:0055001	muscle cell development
0.64	GO:1903078	positive regulation of protein localization to plasma membrane
0.64	GO:0007274	neuromuscular synaptic transmission
0.62	GO:0014902	myotube differentiation
0.62	GO:0035556	intracellular signal transduction
0.47	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.45	GO:0007009	plasma membrane organization

0.56	GO:0042802	identical protein binding
0.52	GO:0046872	metal ion binding

0.61	GO:0005891	voltage-gated calcium channel complex
0.60	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.54	GO:0005654	nucleoplasm
0.54	GO:0005829	cytosol

sp|Q96MF4|CC140_HUMAN
Coiled-coil domain-containing protein 140
Search

0.56	Coiled-coil domain-containing protein 140

sp|Q96MF6|CQ10A_HUMAN
Coenzyme Q-binding protein COQ10 homolog A, mitochondrial
Search

COQ10A

0.94	Coenzyme Q-binding protein COQ10 like protein A, mitochondrial

0.74	GO:0006744	ubiquinone biosynthetic process
0.61	GO:0045333	cellular respiration

0.86

GO:0048039

ubiquinone binding

0.61	GO:0005739	mitochondrion
0.46	GO:0019866	organelle inner membrane

sp|Q96MF7|NSE2_HUMAN
E3 SUMO-protein ligase NSE2
Search

NSMCE2

0.89	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase

0.84	GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion
0.81	GO:0016925	protein sumoylation
0.81	GO:0090398	cellular senescence
0.80	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.80	GO:0000722	telomere maintenance via recombination
0.77	GO:0000724	double-strand break repair via homologous recombination
0.62	GO:0016567	protein ubiquitination

0.83	GO:0019789	SUMO transferase activity
0.63	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0008270	zinc ion binding

0.81	GO:0030915	Smc5-Smc6 complex
0.78	GO:0016605	PML body
0.73	GO:0000781	chromosome, telomeric region

0.63

GO:0004842

sp|Q96MG2|JSPR1_HUMAN
Junctional sarcoplasmic reticulum protein 1
Search

JSRP1

0.97	Junctional sarcoplasmic reticulum protein 1

0.85	GO:0003009	skeletal muscle contraction
0.63	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.42	GO:0006402	mRNA catabolic process
0.41	GO:0072657	protein localization to membrane
0.41	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.41	GO:0006364	rRNA processing
0.40	GO:0008033	tRNA processing
0.35	GO:0007121	bipolar cellular bud site selection
0.35	GO:0051666	actin cortical patch localization
0.35	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation

0.44	GO:0008995	ribonuclease E activity
0.41	GO:0004521	endoribonuclease activity
0.40	GO:0000287	magnesium ion binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0003723	RNA binding
0.37	GO:0005515	protein binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.60	GO:0016529	sarcoplasmic reticulum
0.47	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0098588	bounding membrane of organelle
0.43	GO:0009898	cytoplasmic side of plasma membrane
0.35	GO:0000131	incipient cellular bud site
0.35	GO:0030479	actin cortical patch
0.35	GO:0005935	cellular bud neck
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.2.1

GO:0004553

sp|Q96MG7|NSE3_HUMAN
Non-structural maintenance of chromosomes element 3 homolog
Search

0.83	Melanoma-associated antigen G1

0.64	GO:0070294	renal sodium ion absorption
0.64	GO:0072711	cellular response to hydroxyurea
0.60	GO:0007565	female pregnancy
0.59	GO:0034644	cellular response to UV
0.58	GO:0031398	positive regulation of protein ubiquitination
0.52	GO:0040008	regulation of growth
0.49	GO:0006281	DNA repair
0.48	GO:0048523	negative regulation of cellular process
0.48	GO:0051128	regulation of cellular component organization
0.48	GO:0070534	protein K63-linked ubiquitination

0.51	GO:0046983	protein dimerization activity
0.43	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0005166	neurotrophin p75 receptor binding
0.37	GO:0035091	phosphatidylinositol binding
0.35	GO:0008134	transcription factor binding

0.58	GO:0030915	Smc5-Smc6 complex
0.54	GO:0005829	cytosol
0.54	GO:0005730	nucleolus
0.46	GO:0030904	retromer complex
0.44	GO:0005768	endosome
0.42	GO:0000781	chromosome, telomeric region
0.38	GO:0005654	nucleoplasm
0.37	GO:0031093	platelet alpha granule lumen
0.34	GO:0005576	extracellular region
0.34	GO:0005887	integral component of plasma membrane

0.43

GO:0004842

sp|Q96MG8|PCMD1_HUMAN
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1
Search

PCMTD1

0.97	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation

0.79

GO:0004719

protein-L-isoaspartate (D-aspartate) O-methyltransferase activity

0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.1.1.77

GO:0004719

sp|Q96MH2|HEXI2_HUMAN
Protein HEXIM2
Search

HEXIM2

0.96	Hexamethylene bis-acetamide-inducible 2

0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.78	GO:0000122	negative regulation of transcription by RNA polymerase II
0.78	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.72	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.68	GO:0045786	negative regulation of cell cycle
0.58	GO:1901798	positive regulation of signal transduction by p53 class mediator
0.55	GO:0002218	activation of innate immune response
0.54	GO:0007507	heart development

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.83	GO:0017069	snRNA binding
0.60	GO:0042802	identical protein binding

0.64	GO:0016607	nuclear speck
0.56	GO:0005829	cytosol

sp|Q96MH6|TMM68_HUMAN
Transmembrane protein 68
Search

TMEM68

0.96	Novel protein containing acetyltransferase domain

0.30

GO:0008152

metabolic process

0.63

GO:0016746

transferase activity, transferring acyl groups

0.30

GO:0044425

membrane part

0.63

EC:2.3

GO:0016746

sp|Q96MH7|CE034_HUMAN
Uncharacterized protein C5orf34
Search

sp|Q96MI6|PPM1M_HUMAN
Protein phosphatase 1M
Search

0.12	Putative serine/threonine phosphatase (Fragment)

0.72

GO:0006470

protein dephosphorylation

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.39	GO:0030145	manganese ion binding

0.37

GO:0005634

nucleus

sp|Q96MI9|CBPC4_HUMAN
Cytosolic carboxypeptidase 4
Search

AGBL1

0.91	Cytosolic carboxypeptidase 4

0.68	GO:0021702	cerebellar Purkinje cell differentiation
0.61	GO:0006508	proteolysis
0.54	GO:0035609	C-terminal protein deglutamylation
0.53	GO:0035610	protein side chain deglutamylation
0.46	GO:0021772	olfactory bulb development
0.45	GO:0007628	adult walking behavior
0.45	GO:0050905	neuromuscular process
0.45	GO:0001754	eye photoreceptor cell differentiation
0.44	GO:0060041	retina development in camera-type eye
0.43	GO:0007005	mitochondrion organization

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding
0.46	GO:0015631	tubulin binding

0.43	GO:0005730	nucleolus
0.42	GO:0005829	cytosol
0.39	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.76

EC:3.4.17

GO:0004181

sp|Q96MK2|FA65C_HUMAN
Protein FAM65C
Search

RIPOR3

0.97	RIPOR family member 3

sp|Q96MK3|FA20A_HUMAN
Pseudokinase FAM20A
Search

FAM20A

0.97	FAM20A, golgi associated secretory pathway pseudokinase

0.87	GO:0044691	tooth eruption
0.86	GO:0070166	enamel mineralization
0.79	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.79	GO:0055074	calcium ion homeostasis
0.40	GO:0036179	osteoclast maturation
0.40	GO:0097187	dentinogenesis
0.39	GO:0071895	odontoblast differentiation
0.39	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.38	GO:0030501	positive regulation of bone mineralization
0.38	GO:0045669	positive regulation of osteoblast differentiation

0.84	GO:0043539	protein serine/threonine kinase activator activity
0.39	GO:0030145	manganese ion binding
0.38	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0005509	calcium ion binding

0.73	GO:0005615	extracellular space
0.72	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum

0.38

GO:0004674

sp|Q96MM3|ZFP42_HUMAN
Zinc finger protein 42 homolog
Search

0.75	transcriptional repressor protein YY1

0.49	GO:0048513	animal organ development
0.48	GO:0046546	development of primary male sexual characteristics
0.48	GO:0046545	development of primary female sexual characteristics
0.46	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.46	GO:0032688	negative regulation of interferon-beta production
0.46	GO:0010225	response to UV-C
0.46	GO:0048608	reproductive structure development
0.45	GO:0034644	cellular response to UV
0.44	GO:0009952	anterior/posterior pattern specification
0.44	GO:0007283	spermatogenesis

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046332	SMAD binding
0.45	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0042826	histone deacetylase binding
0.34	GO:0003714	transcription corepressor activity
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0046872	metal ion binding
0.34	GO:0003682	chromatin binding

0.44	GO:0031519	PcG protein complex
0.43	GO:0031011	Ino80 complex
0.42	GO:0005667	transcription factor complex
0.37	GO:0016363	nuclear matrix
0.37	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

sp|Q96MM6|HS12B_HUMAN
Heat shock 70 kDa protein 12B
Search

HSPA12B

0.81	Heat shock protein 12A isoform B

0.73

GO:0002040

sprouting angiogenesis

0.45	GO:0030554	adenyl nucleotide binding
0.44	GO:0097367	carbohydrate derivative binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005515	protein binding

0.45

GO:0070062

extracellular exosome

sp|Q96MM7|H6ST2_HUMAN
Heparan-sulfate 6-O-sulfotransferase 2
Search

0.69	Heparan-sulfate 6-O-sulfotransferase

0.57	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.46	GO:0001525	angiogenesis
0.45	GO:0035295	tube development
0.45	GO:0048666	neuron development
0.45	GO:0048568	embryonic organ development
0.43	GO:0060674	placenta blood vessel development
0.43	GO:0060541	respiratory system development
0.41	GO:0001701	in utero embryonic development
0.41	GO:0061138	morphogenesis of a branching epithelium
0.40	GO:0048592	eye morphogenesis

0.78	GO:0008146	sulfotransferase activity
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.35	GO:0070492	oligosaccharide binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005654	nucleoplasm
0.36	GO:0000139	Golgi membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.78

GO:0008146

sp|Q96MN2|NALP4_HUMAN
NACHT, LRR and PYD domains-containing protein 4
Search

0.87	NLR family pyrin domain containing 4

0.42	GO:0070997	neuron death
0.39	GO:0006954	inflammatory response
0.39	GO:0045087	innate immune response
0.38	GO:0042981	regulation of apoptotic process
0.37	GO:0007283	spermatogenesis
0.34	GO:1904784	NLRP1 inflammasome complex assembly
0.33	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.33	GO:0043068	positive regulation of programmed cell death
0.33	GO:0006915	apoptotic process

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0019904	protein domain specific binding
0.33	GO:0019899	enzyme binding

0.44	GO:0061702	inflammasome complex
0.43	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|Q96MN5|TEAN2_HUMAN
Transcription elongation factor A N-terminal and central domain-containing protein 2
Search

TCEANC2

0.97	Transcription elongation factor A N-terminal and central

0.58	GO:0006351	transcription, DNA-templated
0.56	GO:0006414	translational elongation
0.33	GO:0035725	sodium ion transmembrane transport

0.57	GO:0003746	translation elongation factor activity
0.34	GO:0005272	sodium channel activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q96MN9|ZN488_HUMAN
Zinc finger protein 488
Search

ZNF488

0.61	Zinc finger domain-containing protein (Fragment)

0.52	GO:0014003	oligodendrocyte development
0.43	GO:0048714	positive regulation of oligodendrocyte differentiation
0.39	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0021540	corpus callosum morphogenesis
0.34	GO:0021957	corticospinal tract morphogenesis
0.34	GO:0051567	histone H3-K9 methylation
0.32	GO:0007166	cell surface receptor signaling pathway
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.51	GO:0003676	nucleic acid binding
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.34	GO:0046974	histone methyltransferase activity (H3-K9 specific)
0.33	GO:0003714	transcription corepressor activity
0.33	GO:0003682	chromatin binding
0.33	GO:0004930	G-protein coupled receptor activity

0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q96MP5|ZSWM3_HUMAN
Zinc finger SWIM domain-containing protein 3
Search

ZSWIM3

0.97	Zinc finger SWIM domain-containing protein 3

0.63

GO:0008270

zinc ion binding

0.36

GO:0005634

nucleus

sp|Q96MP8|KCTD7_HUMAN
BTB/POZ domain-containing protein KCTD7
Search

KCTD7

0.96	Potassium channel tetramerization domain containing 7

0.78	GO:0051260	protein homooligomerization
0.64	GO:0090461	glutamate homeostasis
0.62	GO:0060081	membrane hyperpolarization
0.60	GO:0030007	cellular potassium ion homeostasis
0.59	GO:0032411	positive regulation of transporter activity

0.44	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm

sp|Q96MR6|CFA57_HUMAN
Cilia- and flagella-associated protein 57
Search

CFAP57

0.96	Cilia- and flagella-associated protein 57

0.77

GO:0031514

motile cilium

sp|Q96MR7|CA145_HUMAN
Putative uncharacterized protein C1orf145
Search

OBSCN-AS1

0.86	OBSCN antisense RNA 1

sp|Q96MR9|ZN560_HUMAN
Zinc finger protein 560
Search

0.76	Zinc finger protein 426

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding
0.36	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part

sp|Q96MS0|ROBO3_HUMAN
Roundabout homolog 3
Search

ROBO3

0.96	Roundabout guidance receptor 3

0.85	GO:0035385	Roundabout signaling pathway
0.81	GO:0007411	axon guidance
0.45	GO:0001822	kidney development
0.44	GO:0008038	neuron recognition
0.40	GO:0007155	cell adhesion
0.40	GO:0048264	determination of ventral identity
0.39	GO:0048675	axon extension
0.39	GO:0050919	negative chemotaxis
0.39	GO:0050918	positive chemotaxis
0.38	GO:0001764	neuron migration

0.36

GO:0005515

protein binding

0.80	GO:0030424	axon
0.47	GO:0032589	neuron projection membrane
0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0009986	cell surface
0.31	GO:0005634	nucleus

sp|Q96MS3|GL1D1_HUMAN
Glycosyltransferase 1 domain-containing protein 1
Search

GLT1D1

0.97	Glycosyltransferase 1 domain-containing protein 1

0.48	GO:0016740	transferase activity
0.31	GO:0016787	hydrolase activity

0.49	GO:0005829	cytosol
0.38	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.48

EC:2

GO:0016740

sp|Q96MT0|YJ006_HUMAN
Putative uncharacterized protein FLJ31958
Search

sp|Q96MT1|RN145_HUMAN
RING finger protein 145
Search

RNF145

0.97	RING finger protein 145

0.47	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.47	GO:0000209	protein polyubiquitination
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0061515	myeloid cell development

0.62	GO:0008270	zinc ion binding
0.45	GO:0061630	ubiquitin protein ligase activity

0.30

GO:0044425

membrane part

sp|Q96MT3|PRIC1_HUMAN
Prickle-like protein 1
Search

PRICKLE1

0.96	Prickle planar cell polarity protein 1

0.73	GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation
0.66	GO:0001843	neural tube closure
0.66	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.66	GO:0060976	coronary vasculature development
0.66	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.66	GO:0035904	aorta development
0.64	GO:0031398	positive regulation of protein ubiquitination
0.63	GO:0006606	protein import into nucleus
0.57	GO:0045892	negative regulation of transcription, DNA-templated
0.49	GO:0021535	cell migration in hindbrain

0.63	GO:0008270	zinc ion binding
0.32	GO:0005515	protein binding

0.63	GO:0031965	nuclear membrane
0.55	GO:0005829	cytosol

sp|Q96MT4|CF195_HUMAN
Uncharacterized protein encoded by LINC01600
Search

sp|Q96MT7|CFA44_HUMAN
Cilia- and flagella-associated protein 44
Search

0.96	Cilia- and flagella-associated protein 44

0.71	GO:0060285	cilium-dependent cell motility
0.34	GO:0023014	signal transduction by protein phosphorylation
0.34	GO:0000160	phosphorelay signal transduction system
0.34	GO:0090307	mitotic spindle assembly
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.34

GO:0000155

phosphorelay sensor kinase activity

0.63	GO:0031514	motile cilium
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

EC:2.7.3

GO:0000155

sp|Q96MT8|CEP63_HUMAN
Centrosomal protein of 63 kDa
Search

CEP63

0.85	Centrosomal protein of

0.85	GO:0098534	centriole assembly
0.84	GO:0051298	centrosome duplication
0.66	GO:1903251	multi-ciliated epithelial cell differentiation
0.52	GO:0042770	signal transduction in response to DNA damage
0.51	GO:0051225	spindle assembly
0.51	GO:0000077	DNA damage checkpoint
0.45	GO:0051301	cell division
0.44	GO:0097711	ciliary basal body-plasma membrane docking
0.42	GO:0000086	G2/M transition of mitotic cell cycle
0.42	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

0.39

GO:0005515

protein binding

0.76	GO:0005813	centrosome
0.64	GO:0005814	centriole
0.50	GO:0000922	spindle pole
0.38	GO:0005829	cytosol
0.37	GO:0098536	deuterosome

sp|Q96MU5|CQ077_HUMAN
Uncharacterized protein C17orf77
Search

sp|Q96MU6|ZN778_HUMAN
Zinc finger protein 778
Search

0.63	Zinc finger protein 420

0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0010468	regulation of gene expression
0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle

sp|Q96MU7|YTDC1_HUMAN
YTH domain-containing protein 1
Search

YTHDC1

0.95	YTH domain-containing protein 1

0.48	GO:0010608	posttranscriptional regulation of gene expression
0.39	GO:0048024	regulation of mRNA splicing, via spliceosome
0.39	GO:0006376	mRNA splice site selection

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.33	GO:0004386	helicase activity

0.48	GO:0005654	nucleoplasm
0.42	GO:0005886	plasma membrane

sp|Q96MU8|KREM1_HUMAN
Kremen protein 1
Search

KREMEN1

0.96	Kringle containing transmembrane protein 1

0.72	GO:0030279	negative regulation of ossification
0.70	GO:0060173	limb development
0.68	GO:0016055	Wnt signaling pathway
0.65	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.61	GO:0006915	apoptotic process
0.53	GO:0048903	anterior lateral line neuromast hair cell differentiation
0.51	GO:0048916	posterior lateral line development
0.49	GO:0001889	liver development
0.48	GO:0001525	angiogenesis

0.30

GO:0016020

membrane

sp|Q96MV1|TMM56_HUMAN
Transmembrane protein 56
Search

0.94	Transmembrane protein 56-B

0.33	GO:0004408	holocytochrome-c synthase activity
0.32	GO:0046872	metal ion binding

0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:4.4.1.17

GO:0004408

sp|Q96MV8|ZDH15_HUMAN
Palmitoyltransferase ZDHHC15
Search

ZDHHC15

0.55	Palmitoyltransferase

0.59	GO:0018345	protein palmitoylation
0.57	GO:0016188	synaptic vesicle maturation
0.45	GO:0045184	establishment of protein localization

0.80

GO:0019706

protein-cysteine S-palmitoyltransferase activity

0.52	GO:0005794	Golgi apparatus
0.46	GO:0055038	recycling endosome membrane
0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0005887	integral component of plasma membrane
0.36	GO:0070062	extracellular exosome

0.80

EC:2.3.1.225

GO:0019706

sp|Q96MW1|CCD43_HUMAN
Coiled-coil domain-containing protein 43
Search

CCDC43

0.96	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 43

0.37

GO:0005515

protein binding

0.68

GO:0005829

cytosol

sp|Q96MW5|COG8_HUMAN
Conserved oligomeric Golgi complex subunit 8
Search

COG8

0.87	Oligomeric Golgi complex subunit 8

0.71	GO:0006891	intra-Golgi vesicle-mediated transport
0.58	GO:0015031	protein transport
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0005515	protein binding
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.79	GO:0017119	Golgi transport complex
0.65	GO:0000139	Golgi membrane
0.35	GO:0005802	trans-Golgi network
0.30	GO:0044425	membrane part

0.33

GO:0016616

sp|Q96MW7|TIGD1_HUMAN
Tigger transposable element-derived protein 1
Search

TIGD1

0.34	Tigger transposable element-derived protein 1

0.34	GO:0072137	condensed mesenchymal cell proliferation
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0072006	nephron development
0.32	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.50	GO:0003677	DNA binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0004519	endonuclease activity

0.35	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96MX0|CKLF3_HUMAN
CKLF-like MARVEL transmembrane domain-containing protein 3
Search

CMTM3

0.97	CKLF like MARVEL transmembrane domain containing 3

0.64	GO:0050861	positive regulation of B cell receptor signaling pathway
0.38	GO:0010469	regulation of receptor activity
0.37	GO:0006935	chemotaxis

0.39

GO:0005125

cytokine activity

0.58	GO:0031965	nuclear membrane
0.41	GO:0005737	cytoplasm
0.37	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|Q96MX3|ZNF48_HUMAN
Zinc finger protein 48
Search

0.10	Zinc finger protein 48

0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:0010468	regulation of gene expression
0.36	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding

0.40	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle

sp|Q96MX6|WDR92_HUMAN
WD repeat-containing protein 92
Search

WDR92

0.94	LOW QUALITY PROTEIN: WD repeat-containing protein 92

0.58

GO:0006915

apoptotic process

0.71	GO:0043130	ubiquitin binding
0.52	GO:0005509	calcium ion binding

sp|Q96MY1|NOL4L_HUMAN
Nucleolar protein 4-like
Search

NOL4L

0.97	Nucleolar protein 4 like

0.36

GO:0005515

protein binding

0.68	GO:0031981	nuclear lumen
0.60	GO:0005829	cytosol
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q96MY7|F161B_HUMAN
Protein FAM161B
Search

sp|Q96MZ0|GD1L1_HUMAN
Ganglioside-induced differentiation-associated protein 1-like 1
Search

GDAP1L1

0.97	Ganglioside-induced differentiation-associated protein 1-like 1

0.46	GO:0006749	glutathione metabolic process
0.41	GO:0032526	response to retinoic acid
0.41	GO:0008053	mitochondrial fusion
0.41	GO:0000266	mitochondrial fission
0.40	GO:0006626	protein targeting to mitochondrion
0.38	GO:0071305	cellular response to vitamin D

0.47

GO:0004364

glutathione transferase activity

0.40	GO:0031307	integral component of mitochondrial outer membrane
0.38	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.47

EC:2.5.1.18

GO:0004364

sp|Q96MZ4|F218A_HUMAN
Protein FAM218A
Search

sp|Q96N03|VTM2L_HUMAN
V-set and transmembrane domain-containing protein 2-like protein
Search

VSTM2L

0.97	V-set and transmembrane domain containing 2 like

0.62

GO:0043524

negative regulation of neuron apoptotic process

0.34

GO:0005515

protein binding

0.51	GO:0005576	extracellular region
0.41	GO:0005737	cytoplasm
0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q96N06|SPT33_HUMAN
Spermatogenesis-associated protein 33
Search

SPATA33

0.97	Spermatogenesis-associated protein 33

0.61	GO:0005634	nucleus
0.55	GO:0005829	cytosol

sp|Q96N11|CG026_HUMAN
Uncharacterized protein C7orf26
Search

0.37	GO:0055114	oxidation-reduction process
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.50	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.45	GO:0008080	N-acetyltransferase activity
0.42	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.41	GO:0020037	heme binding
0.41	GO:0005506	iron ion binding
0.36	GO:0004930	G-protein coupled receptor activity
0.36	GO:0030246	carbohydrate binding

0.30

GO:0044425

membrane part

0.50

EC:2.3.1.225

GO:0019706

sp|Q96N16|JKIP1_HUMAN
Janus kinase and microtubule-interacting protein 1
Search

JAKMIP1

0.93	Janus kinase and microtubule-interacting protein 1

0.53	GO:0050890	cognition
0.50	GO:0016310	phosphorylation
0.37	GO:0015031	protein transport
0.34	GO:0043087	regulation of GTPase activity
0.31	GO:0007411	axon guidance
0.31	GO:0000226	microtubule cytoskeleton organization

0.77	GO:0019900	kinase binding
0.73	GO:0008017	microtubule binding
0.56	GO:0050811	GABA receptor binding
0.54	GO:0019894	kinesin binding
0.51	GO:0016301	kinase activity
0.43	GO:0003723	RNA binding
0.31	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.50	GO:0019898	extrinsic component of membrane
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0005874	microtubule
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.31

EC:3.5

GO:0016810

sp|Q96N19|G137A_HUMAN
Integral membrane protein GPR137
Search

GPR137

0.71	G protein-coupled receptor 137

0.30

GO:0044425

membrane part

sp|Q96N20|ZN75A_HUMAN
Zinc finger protein 75A
Search

ZNF75A

0.91	Zinc finger protein 75A

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.47	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.49	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.49	GO:0005634	nucleus
0.32	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

sp|Q96N21|AP4AT_HUMAN
AP-4 complex accessory subunit Tepsin
Search

TEPSIN

0.84	AP-4 complex accessory subunit Tepsin

0.42

GO:0005515

protein binding

0.86	GO:0030124	AP-4 adaptor complex
0.85	GO:0032588	trans-Golgi network membrane
0.80	GO:0016607	nuclear speck
0.79	GO:0031312	extrinsic component of organelle membrane
0.79	GO:0031965	nuclear membrane
0.77	GO:0030662	coated vesicle membrane
0.49	GO:0005829	cytosol

sp|Q96N22|ZN681_HUMAN
Zinc finger protein 681
Search

0.86	Zinc finger protein 92

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.45	GO:0043508	negative regulation of JUN kinase activity
0.45	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.45	GO:0045671	negative regulation of osteoclast differentiation
0.44	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.44	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.42	GO:0019221	cytokine-mediated signaling pathway

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003714	transcription corepressor activity

0.45	GO:0005622	intracellular
0.42	GO:0043227	membrane-bounded organelle
0.35	GO:0043233	organelle lumen
0.34	GO:0043228	non-membrane-bounded organelle

sp|Q96N23|CFA54_HUMAN
Cilia- and flagella-associated protein 54
Search

CFAP54

0.97	Cilia- and flagella-associated protein 54

0.69	GO:0060294	cilium movement involved in cell motility
0.62	GO:0007283	spermatogenesis
0.61	GO:0060271	cilium assembly
0.50	GO:0030154	cell differentiation

0.71	GO:0005929	cilium
0.55	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.49	GO:0044430	cytoskeletal part
0.30	GO:0031224	intrinsic component of membrane

sp|Q96N28|PLD3A_HUMAN
PRELI domain containing protein 3A
Search

PRELID3A

0.97	PRELI domain containing protein 3A

0.53	GO:0015914	phospholipid transport
0.53	GO:1903955	positive regulation of protein targeting to mitochondrion

0.59	GO:1990050	phosphatidic acid transporter activity
0.33	GO:0005515	protein binding

0.79

GO:0005758

mitochondrial intermembrane space

sp|Q96N35|TMM83_HUMAN
Putative uncharacterized protein encoded by LINC00052
Search

sp|Q96N38|ZN714_HUMAN
Zinc finger protein 714
Search

ZNF430

0.83	Zinc finger protein 626

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression
0.35	GO:0097659	nucleic acid-templated transcription
0.34	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.44	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle

sp|Q96N46|TTC14_HUMAN
Tetratricopeptide repeat protein 14
Search

TTC14

0.96	Tetratricopeptide repeat protein 14

0.30

GO:0008152

metabolic process

0.50	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding
0.33	GO:0016853	isomerase activity

0.33

EC:5

GO:0016853

sp|Q96N53|CK037_HUMAN
Putative uncharacterized protein encoded by LINC00167
Search

sp|Q96N58|ZN578_HUMAN
Zinc finger protein 578
Search

0.60	Zinc finger protein 860

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.45

GO:0005622

intracellular

sp|Q96N64|PWP2A_HUMAN
PWWP domain-containing protein 2A
Search

PWWP2A

0.92	PWWP domain-containing protein 2A

0.45	GO:0001755	neural crest cell migration
0.43	GO:0001654	eye development
0.43	GO:0060322	head development

0.77	GO:0042393	histone binding
0.76	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

sp|Q96N66|MBOA7_HUMAN
Lysophospholipid acyltransferase 7
Search

MBOAT7

0.97	Membrane bound O-acyltransferase domain containing 7

0.59	GO:0021819	layer formation in cerebral cortex
0.58	GO:0021591	ventricular system development
0.51	GO:0046488	phosphatidylinositol metabolic process
0.38	GO:0008654	phospholipid biosynthetic process

0.56	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0005515	protein binding

0.35	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.56

EC:2.3

GO:0016746

sp|Q96N67|DOCK7_HUMAN
Dedicator of cytokinesis protein 7
Search

DOCK7

0.95	Dedicator of cytokinesis protein 7

0.76	GO:0007264	small GTPase mediated signal transduction
0.65	GO:0065009	regulation of molecular function
0.58	GO:0045200	establishment of neuroblast polarity
0.57	GO:1904754	positive regulation of vascular associated smooth muscle cell migration
0.54	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.51	GO:0007409	axonogenesis
0.50	GO:0000226	microtubule cytoskeleton organization
0.41	GO:0022027	interkinetic nuclear migration
0.38	GO:0050767	regulation of neurogenesis
0.38	GO:0002244	hematopoietic progenitor cell differentiation

0.74	GO:0005085	guanyl-nucleotide exchange factor activity
0.54	GO:0048365	Rac GTPase binding

0.52	GO:0008180	COP9 signalosome
0.37	GO:0005925	focal adhesion
0.37	GO:0030424	axon
0.35	GO:0045178	basal part of cell
0.35	GO:0030426	growth cone
0.30	GO:0016021	integral component of membrane

sp|Q96N68|CR015_HUMAN
Putative uncharacterized protein C18orf15
Search

sp|Q96N76|HUTU_HUMAN
Urocanate hydratase
Search

UROC1

0.50	Urocanate hydratase

0.49	GO:0006548	histidine catabolic process
0.37	GO:0043606	formamide metabolic process
0.37	GO:0015942	formate metabolic process
0.37	GO:0006536	glutamate metabolic process

0.82	GO:0016153	urocanate hydratase activity
0.33	GO:0003676	nucleic acid binding

0.44	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.82	EC:4.2.1.49	GO:0016153
0.82	KEGG:R02914	GO:0016153

sp|Q96N77|ZN641_HUMAN
Zinc finger protein 641
Search

0.65	Zinc finger protein 641

0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0045454	cell redox homeostasis

0.51	GO:0003676	nucleic acid binding
0.43	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003756	protein disulfide isomerase activity
0.32	GO:0016787	hydrolase activity

0.43	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0005829	cytosol
0.36	GO:0044446	intracellular organelle part
0.35	GO:0015630	microtubule cytoskeleton
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:5.3.4.1

GO:0003756

sp|Q96N87|S6A18_HUMAN
Sodium-dependent neutral amino acid transporter B(0)AT3
Search

SLC6A18

0.64	Sodium-dependent neutral amino acid transporter B(0)AT3

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.53	GO:0006865	amino acid transport
0.46	GO:0007584	response to nutrient
0.44	GO:0006972	hyperosmotic response

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.48	GO:0015171	amino acid transmembrane transporter activity
0.41	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.61	GO:0031526	brush border membrane
0.41	GO:0070062	extracellular exosome

sp|Q96N95|ZN396_HUMAN
Zinc finger protein 396
Search

0.97	Zinc finger protein 24

0.59	GO:0042552	myelination
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.54	GO:0051254	positive regulation of RNA metabolic process
0.54	GO:0051253	negative regulation of RNA metabolic process
0.54	GO:0010558	negative regulation of macromolecule biosynthetic process
0.54	GO:0031327	negative regulation of cellular biosynthetic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process

0.60	GO:0003700	DNA binding transcription factor activity
0.51	GO:0046872	metal ion binding
0.49	GO:0003676	nucleic acid binding
0.41	GO:0043621	protein self-association
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity

0.60	GO:0005634	nucleus
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol

sp|Q96N96|SPT13_HUMAN
Spermatogenesis-associated protein 13
Search

ARHGEF4

0.90	Spermatogenesis-associated protein 13

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.43	GO:0046847	filopodium assembly
0.43	GO:0030032	lamellipodium assembly
0.42	GO:0035556	intracellular signal transduction
0.41	GO:0030334	regulation of cell migration
0.41	GO:0016477	cell migration

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.42	GO:0048365	Rac GTPase binding
0.40	GO:0042802	identical protein binding

0.42	GO:0032587	ruffle membrane
0.42	GO:0030175	filopodium
0.42	GO:0030027	lamellipodium
0.41	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.35	GO:0005581	collagen trimer
0.34	GO:0005576	extracellular region

sp|Q96NA2|RILP_HUMAN
Rab-interacting lysosomal protein
Search

RILP

0.96	Rab-interacting lysosomal protein (Fragment)

0.73	GO:0010796	regulation of multivesicular body size
0.71	GO:0045022	early endosome to late endosome transport
0.71	GO:0070676	intralumenal vesicle formation
0.69	GO:0008333	endosome to lysosome transport
0.67	GO:0042177	negative regulation of protein catabolic process
0.66	GO:0032509	endosome transport via multivesicular body sorting pathway
0.64	GO:0045732	positive regulation of protein catabolic process
0.53	GO:0060271	cilium assembly
0.41	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.38	GO:0015031	protein transport

0.71	GO:0051959	dynein light intermediate chain binding
0.68	GO:0046983	protein dimerization activity
0.65	GO:0017137	Rab GTPase binding

0.65	GO:0005770	late endosome
0.65	GO:0005764	lysosome
0.63	GO:0010008	endosome membrane
0.57	GO:0005829	cytosol
0.55	GO:0036064	ciliary basal body
0.51	GO:0005739	mitochondrion
0.51	GO:0043234	protein complex
0.43	GO:0030670	phagocytic vesicle membrane
0.41	GO:0098852	lytic vacuole membrane

sp|Q96NA8|TSNA1_HUMAN
t-SNARE domain-containing protein 1
Search

TSNARE1

0.92	LOW QUALITY PROTEIN: t-SNARE domain-containing protein 1

0.67	GO:0016192	vesicle-mediated transport
0.54	GO:0090174	organelle membrane fusion
0.52	GO:0016050	vesicle organization
0.52	GO:0140056	organelle localization by membrane tethering
0.49	GO:0006886	intracellular protein transport
0.47	GO:0006915	apoptotic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.54	GO:0005484	SNAP receptor activity
0.53	GO:0000149	SNARE binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.54	GO:0031201	SNARE complex
0.47	GO:0012505	endomembrane system
0.41	GO:0005634	nucleus
0.33	GO:0005801	cis-Golgi network
0.30	GO:0016021	integral component of membrane

sp|Q96NB1|FOPNL_HUMAN
LisH domain-containing protein FOPNL
Search

FOPNL

0.97	LisH domain-containing protein FOPNL

0.84	GO:0034453	microtubule anchoring
0.39	GO:0060271	cilium assembly
0.39	GO:0007018	microtubule-based movement

0.39	GO:0051015	actin filament binding
0.39	GO:0003777	microtubule motor activity
0.39	GO:0008017	microtubule binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005815	microtubule organizing center
0.52	GO:0031514	motile cilium
0.51	GO:0044441	ciliary part
0.44	GO:0005634	nucleus
0.39	GO:0016459	myosin complex
0.35	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

sp|Q96NB2|SFXN2_HUMAN
Sideroflexin-2
Search

SFXN2

0.81	Sideroflexin

0.60	GO:0034220	ion transmembrane transport
0.37	GO:0055072	iron ion homeostasis

0.60

GO:0015075

ion transmembrane transporter activity

0.59	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96NB3|ZN830_HUMAN
Zinc finger protein 830
Search

ZNF830

0.53	Ovum mutant candidate protein 1

0.67	GO:0048162	multi-layer follicle stage
0.65	GO:0060729	intestinal epithelial structure maintenance
0.64	GO:0001832	blastocyst growth
0.62	GO:0033314	mitotic DNA replication checkpoint
0.62	GO:0001541	ovarian follicle development
0.62	GO:0048478	replication fork protection
0.61	GO:0044773	mitotic DNA damage checkpoint
0.60	GO:0033260	nuclear DNA replication
0.57	GO:0043066	negative regulation of apoptotic process
0.51	GO:0051276	chromosome organization

0.60	GO:0008270	zinc ion binding
0.49	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding

0.59	GO:0016607	nuclear speck
0.40	GO:0005694	chromosome
0.32	GO:0000814	ESCRT II complex

sp|Q96NC0|ZMAT2_HUMAN
Zinc finger matrin-type protein 2
Search

ZMAT2

0.95	Zinc finger matrin-type protein 2

0.45	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006427	histidyl-tRNA aminoacylation

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.36	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:6.1

GO:0016875

sp|Q96ND0|F210A_HUMAN
Protein FAM210A
Search

0.49	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|Q96ND8|ZN583_HUMAN
Zinc finger protein 583
Search

0.74	Zinc finger protein 583

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.35	GO:0043230	extracellular organelle
0.34	GO:0005615	extracellular space
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part

sp|Q96NE9|FRMD6_HUMAN
FERM domain-containing protein 6
Search

FRMD6

0.95	FERM domain-containing protein 6

0.61	GO:0003383	apical constriction
0.54	GO:0032970	regulation of actin filament-based process
0.50	GO:0034613	cellular protein localization
0.49	GO:0031032	actomyosin structure organization

0.47	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0005515	protein binding

0.69	GO:0005856	cytoskeleton
0.56	GO:0043296	apical junction complex
0.35	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm

sp|Q96NF6|CH049_HUMAN
Putative uncharacterized protein C8orf49
Search

sp|Q96NG3|TTC25_HUMAN
Tetratricopeptide repeat protein 25
Search

TTC25

0.96	Tetratricopeptide repeat protein 25

0.50	GO:0009214	cyclic nucleotide catabolic process
0.38	GO:0032474	otolith morphogenesis
0.38	GO:0061371	determination of heart left/right asymmetry
0.37	GO:0060271	cilium assembly
0.35	GO:0098869	cellular oxidant detoxification
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0005975	carbohydrate metabolic process

0.49	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
0.37	GO:0005515	protein binding
0.36	GO:0004096	catalase activity
0.34	GO:0020037	heme binding
0.32	GO:0030246	carbohydrate binding
0.32	GO:0016853	isomerase activity

0.47	GO:0005737	cytoplasm
0.41	GO:0005856	cytoskeleton
0.41	GO:0042995	cell projection
0.30	GO:0016020	membrane

0.49

EC:3.1.4.37

GO:0004113

sp|Q96NG5|ZN558_HUMAN
Zinc finger protein 558
Search

LOC105998767

0.70	Zinc finger protein 558

0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0010468	regulation of gene expression
0.35	GO:0097659	nucleic acid-templated transcription
0.34	GO:0031110	regulation of microtubule polymerization or depolymerization
0.34	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle

sp|Q96NG8|ZN582_HUMAN
Zinc finger protein 582
Search

ZNF582

0.72	Zinc finger protein 582

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity

0.44	GO:0031965	nuclear membrane
0.37	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q96NH3|BROMI_HUMAN
Protein broad-minded
Search

TBC1D32

0.97	TBC1 domain family member 32

0.87	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.87	GO:0003406	retinal pigment epithelium development
0.85	GO:0061512	protein localization to cilium
0.85	GO:0042733	embryonic digit morphogenesis
0.85	GO:0002088	lens development in camera-type eye
0.85	GO:1905515	non-motile cilium assembly
0.84	GO:0007368	determination of left/right symmetry
0.80	GO:0007507	heart development

sp|Q96NI6|LRFN5_HUMAN
Leucine-rich repeat and fibronectin type-III domain-containing protein 5
Search

LRFN5

0.97	Leucine-rich repeat and fibronectin type-III domain-containing

0.47

GO:0007409

axonogenesis

0.48	GO:0009986	cell surface
0.46	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q96NI8|ZN570_HUMAN
Zinc finger protein 570
Search

0.63	Zinc finger protein 25

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044422	organelle part

sp|Q96NJ1|YI001_HUMAN
Uncharacterized protein FLJ30774
Search

sp|Q96NJ3|ZN285_HUMAN
Zinc finger protein 285
Search

0.46	Zinc finger protein 988

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.45

GO:0005622

intracellular

sp|Q96NJ5|KLH32_HUMAN
Kelch-like protein 32
Search

KLHL32

0.96	Kelch like family member 32

0.84	GO:0008584	male gonad development
0.83	GO:0007286	spermatid development
0.82	GO:0009566	fertilization
0.72	GO:0016567	protein ubiquitination

0.73	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0005515	protein binding

0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.49	GO:0005737	cytoplasm

0.73

GO:0004842

sp|Q96NJ6|ZFP3_HUMAN
Zinc finger protein 3 homolog
Search

0.70	Zinc finger protein 3

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.41	GO:0071294	cellular response to zinc ion
0.40	GO:0006351	transcription, DNA-templated
0.38	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0042254	ribosome biogenesis
0.32	GO:0006796	phosphate-containing compound metabolic process
0.32	GO:0007018	microtubule-based movement

0.51	GO:0003676	nucleic acid binding
0.47	GO:0046872	metal ion binding
0.46	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004427	inorganic diphosphatase activity
0.32	GO:0003777	microtubule motor activity
0.32	GO:0008017	microtubule binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005634	nucleus
0.39	GO:0015630	microtubule cytoskeleton
0.38	GO:0005829	cytosol
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0005886	plasma membrane

0.34	EC:3.6.1.1	GO:0004427
0.34	KEGG:R00004	GO:0004427

sp|Q96NK8|NDF6_HUMAN
Neurogenic differentiation factor 6
Search

NEUROD6

0.92	Neurogenic differentiation factor

0.74	GO:0007399	nervous system development
0.70	GO:0030154	cell differentiation
0.58	GO:0060322	head development
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0048513	animal organ development
0.55	GO:1903508	positive regulation of nucleic acid-templated transcription
0.54	GO:0010628	positive regulation of gene expression
0.48	GO:0051960	regulation of nervous system development
0.48	GO:0060284	regulation of cell development

0.68	GO:0046983	protein dimerization activity
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.59	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0001105	RNA polymerase II transcription coactivator activity
0.45	GO:0001102	RNA polymerase II activating transcription factor binding
0.43	GO:0003682	chromatin binding
0.39	GO:0003714	transcription corepressor activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0008484	sulfuric ester hydrolase activity

0.59	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.38	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.32	GO:0070013	intracellular organelle lumen

0.33

EC:3.1.6

GO:0008484

sp|Q96NL0|RUN3B_HUMAN
RUN domain-containing protein 3B
Search

RUNDC3B

0.97	RUN domain-containing protein 3B

0.65

GO:0031284

positive regulation of guanylate cyclase activity

0.65	GO:0030250	guanylate cyclase activator activity
0.65	GO:0051428	peptide hormone receptor binding

0.53	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q96NL1|TMM74_HUMAN
Transmembrane protein 74
Search

TMEM74

0.97	Transmembrane protein 74

0.75

GO:0006914

autophagy

0.34

GO:0005515

protein binding

0.39	GO:0000421	autophagosome membrane
0.38	GO:0005765	lysosomal membrane
0.37	GO:0031410	cytoplasmic vesicle
0.30	GO:0044425	membrane part

sp|Q96NL3|ZN599_HUMAN
Zinc finger protein 599
Search

ZNF599

0.78	Zinc finger protein 264

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.34	GO:0006468	protein phosphorylation

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.38	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle

sp|Q96NL6|SCLT1_HUMAN
Sodium channel and clathrin linker 1
Search

SCLT1

0.97	Sodium channel and clathrin linker 1

0.80	GO:0060271	cilium assembly
0.50	GO:0045162	clustering of voltage-gated sodium channels
0.42	GO:0065009	regulation of molecular function
0.41	GO:0140056	organelle localization by membrane tethering

0.49	GO:0017080	sodium channel regulator activity
0.48	GO:0008022	protein C-terminus binding
0.47	GO:0030276	clathrin binding

0.86	GO:0097539	ciliary transition fiber
0.83	GO:0005814	centriole
0.78	GO:0005813	centrosome
0.48	GO:0071439	clathrin complex
0.44	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q96NL8|CH037_HUMAN
Protein C8orf37
Search

0.38	GO:0070121	Kupffer's vesicle development
0.38	GO:0032402	melanosome transport

0.37

GO:0005515

protein binding

0.85	GO:0097546	ciliary base
0.72	GO:0030054	cell junction
0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96NM4|TOX2_HUMAN
TOX high mobility group box family member 2
Search

TOX2

0.96	TOX high mobility group box family member 2

0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0006366	transcription by RNA polymerase II
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0043524	negative regulation of neuron apoptotic process
0.35	GO:0034698	response to gonadotropin
0.35	GO:0008585	female gonad development

0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0051219	phosphoprotein binding
0.41	GO:0003682	chromatin binding
0.40	GO:0042803	protein homodimerization activity
0.35	GO:0001085	RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.40	GO:0072357	PTW/PP1 phosphatase complex

sp|Q96NN9|AIFM3_HUMAN
Apoptosis-inducing factor 3
Search

AIFM3

0.94	Apoptosis inducing factor, mitochondria associated 3

0.73	GO:0097194	execution phase of apoptosis
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0072114	pronephros morphogenesis

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.54	GO:0016491	oxidoreductase activity

0.62	GO:0005783	endoplasmic reticulum
0.60	GO:0005829	cytosol
0.55	GO:0031966	mitochondrial membrane
0.55	GO:0019866	organelle inner membrane

0.54

GO:0016491

sp|Q96NR2|C2AS1_HUMAN
Putative uncharacterized protein C20orf166-AS1
Search

sp|Q96NR3|PTHD1_HUMAN
Patched domain-containing protein 1
Search

PTCHD1

0.97	Patched domain-containing protein 1

0.58	GO:0021794	thalamus development
0.56	GO:0035176	social behavior
0.55	GO:0007224	smoothened signaling pathway
0.55	GO:0050890	cognition

0.42	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q96NR7|WWAS2_HUMAN
Putative uncharacterized protein WWC2-AS2
Search

sp|Q96NR8|RDH12_HUMAN
Retinol dehydrogenase 12
Search

RDH12

0.76	Androgen-regulated short-chain dehydrogenase/reductase 1

0.82	GO:0042572	retinol metabolic process
0.70	GO:0016062	adaptation of rhodopsin mediated signaling
0.67	GO:0042574	retinal metabolic process
0.48	GO:0055114	oxidation-reduction process
0.41	GO:0007601	visual perception
0.38	GO:0045494	photoreceptor cell maintenance
0.35	GO:0006886	intracellular protein transport
0.35	GO:0016192	vesicle-mediated transport

0.71	GO:0004745	retinol dehydrogenase activity
0.69	GO:0052650	NADP-retinol dehydrogenase activity
0.35	GO:0005515	protein binding
0.35	GO:0004022	alcohol dehydrogenase (NAD) activity

0.66	GO:0001917	photoreceptor inner segment
0.42	GO:0042622	photoreceptor outer segment membrane
0.41	GO:0005622	intracellular
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0016021	integral component of membrane

0.71	EC:1.1.1.105	GO:0004745
0.69	KEGG:R08379	GO:0052650

sp|Q96NS1|YPEL4_HUMAN
Protein yippee-like 4
Search

sp|Q96NS5|ASB16_HUMAN
Ankyrin repeat and SOCS box protein 16
Search

ASB16

0.90	LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 16

0.71	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.38	GO:0043687	post-translational protein modification

0.51	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0004842	ubiquitin-protein transferase activity

0.50	GO:0000151	ubiquitin ligase complex
0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

0.49

GO:0004842

sp|Q96NS8|CLUP3_HUMAN
Putative protein CLUHP3
Search

sp|Q96NT0|CC115_HUMAN
Coiled-coil domain-containing protein 115
Search

CCDC115

0.88	Coiled-coil domain-containing protein 115

0.85	GO:1905146	lysosomal protein catabolic process
0.85	GO:0007042	lysosomal lumen acidification
0.83	GO:0036295	cellular response to increased oxygen levels
0.72	GO:0006879	cellular iron ion homeostasis

0.57

GO:0051082

unfolded protein binding

0.78	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.77	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.76	GO:0030137	COPI-coated vesicle
0.75	GO:0005764	lysosome
0.70	GO:0005783	endoplasmic reticulum
0.64	GO:0031312	extrinsic component of organelle membrane
0.58	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.55	GO:0031984	organelle subcompartment
0.46	GO:0005768	endosome

sp|Q96NT1|NP1L5_HUMAN
Nucleosome assembly protein 1-like 5
Search

NAP1L5

0.97	Nucleosome assembly protein 1 like 5

0.78	GO:0006334	nucleosome assembly
0.50	GO:0071442	positive regulation of histone H3-K14 acetylation
0.50	GO:2000035	regulation of stem cell division
0.49	GO:2000617	positive regulation of histone H3-K9 acetylation
0.47	GO:0045666	positive regulation of neuron differentiation
0.34	GO:0007015	actin filament organization
0.34	GO:0000412	histone peptidyl-prolyl isomerization
0.34	GO:0051694	pointed-end actin filament capping
0.33	GO:0051261	protein depolymerization
0.32	GO:0006629	lipid metabolic process

0.46	GO:0042393	histone binding
0.45	GO:0003682	chromatin binding
0.35	GO:0008092	cytoskeletal protein binding
0.34	GO:0005528	FK506 binding
0.33	GO:0071949	FAD binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0046983	protein dimerization activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:5.2.1.8

GO:0003755

sp|Q96NT3|GUCD1_HUMAN
Protein GUCD1
Search

GUCD1

0.96	Guanylyl cyclase domain-containing protein 1

sp|Q96NT5|PCFT_HUMAN
Proton-coupled folate transporter
Search

SLC46A1

0.83	Proton-coupled folate transporter

0.67	GO:1904447	folic acid import across plasma membrane
0.66	GO:0051958	methotrexate transport
0.57	GO:0015886	heme transport
0.49	GO:1902600	hydrogen ion transmembrane transport
0.38	GO:0098829	intestinal folate absorption
0.36	GO:0046655	folic acid metabolic process
0.35	GO:0006879	cellular iron ion homeostasis

0.65	GO:0008517	folic acid transmembrane transporter activity
0.58	GO:0015232	heme transporter activity
0.49	GO:0015078	hydrogen ion transmembrane transporter activity
0.43	GO:0015350	methotrexate transmembrane transporter activity
0.43	GO:0005542	folic acid binding

0.60	GO:0016324	apical plasma membrane
0.42	GO:0031526	brush border membrane
0.41	GO:0005737	cytoplasm
0.37	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q96NU0|CNT3B_HUMAN
Contactin-associated protein-like 3B
Search

CNTNAP4

0.84	Contactin associated protein like 4

0.67	GO:2000821	regulation of grooming behavior
0.65	GO:0032225	regulation of synaptic transmission, dopaminergic
0.64	GO:0032228	regulation of synaptic transmission, GABAergic

0.44

GO:0005509

calcium ion binding

0.63	GO:0042734	presynaptic membrane
0.60	GO:0030425	dendrite
0.30	GO:0031224	intrinsic component of membrane

sp|Q96NU1|SAM11_HUMAN
Sterile alpha motif domain-containing protein 11
Search

SAMD11

0.94	Sterile alpha motif domain-containing protein 11

0.41

GO:0000122

negative regulation of transcription by RNA polymerase II

0.53	GO:0003677	DNA binding
0.44	GO:0032093	SAM domain binding
0.44	GO:0042731	PH domain binding
0.43	GO:0043621	protein self-association

0.43

GO:0005634

nucleus

sp|Q96NU7|HUTI_HUMAN
Probable imidazolonepropionase
Search

AMDHD1

0.96	Amidohydrolase domain containing 1

0.78	GO:0043606	formamide metabolic process
0.78	GO:0006548	histidine catabolic process
0.73	GO:0006536	glutamate metabolic process
0.40	GO:0015942	formate metabolic process
0.37	GO:0000387	spliceosomal snRNP assembly

0.75	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
0.35	GO:0046872	metal ion binding

0.49	GO:0005737	cytoplasm
0.36	GO:0005681	spliceosomal complex
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.5.2

GO:0016812

sp|Q96NW4|ANR27_HUMAN
Ankyrin repeat domain-containing protein 27
Search

ANKRD27

0.95	Ankyrin repeat domain-containing protein 27

0.86	GO:1990126	retrograde transport, endosome to plasma membrane
0.85	GO:0045022	early endosome to late endosome transport
0.85	GO:0035544	negative regulation of SNARE complex assembly
0.85	GO:0035646	endosome to melanosome transport
0.84	GO:0050775	positive regulation of dendrite morphogenesis
0.75	GO:0048812	neuron projection morphogenesis
0.65	GO:0065009	regulation of molecular function
0.42	GO:0015031	protein transport

0.81	GO:0000149	SNARE binding
0.80	GO:0017137	Rab GTPase binding
0.74	GO:0005085	guanyl-nucleotide exchange factor activity
0.42	GO:0005096	GTPase activator activity

0.86	GO:0097422	tubular endosome
0.82	GO:0042470	melanosome
0.80	GO:0005770	late endosome
0.80	GO:0005769	early endosome
0.76	GO:0030133	transport vesicle
0.76	GO:0005764	lysosome
0.73	GO:0043005	neuron projection
0.68	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.45	GO:0030659	cytoplasmic vesicle membrane

sp|Q96NW7|LRRC7_HUMAN
Leucine-rich repeat-containing protein 7
Search

LRRC7

0.95	Leucine-rich repeat-containing protein 7

0.72	GO:0010976	positive regulation of neuron projection development
0.54	GO:0023052	signaling
0.54	GO:0007154	cell communication
0.52	GO:0051716	cellular response to stimulus
0.46	GO:0043312	neutrophil degranulation
0.40	GO:0097120	receptor localization to synapse
0.40	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.40	GO:0043113	receptor clustering
0.39	GO:0046710	GDP metabolic process
0.38	GO:0046037	GMP metabolic process

0.43	GO:0005515	protein binding
0.39	GO:0004385	guanylate kinase activity

0.67	GO:0043005	neuron projection
0.53	GO:0014069	postsynaptic density
0.51	GO:0045211	postsynaptic membrane
0.48	GO:0030054	cell junction
0.48	GO:0035580	specific granule lumen
0.40	GO:0005576	extracellular region
0.40	GO:0008328	ionotropic glutamate receptor complex
0.39	GO:0016323	basolateral plasma membrane
0.34	GO:0030175	filopodium
0.33	GO:0036477	somatodendritic compartment

0.39

EC:2.7.4.8

GO:0004385

sp|Q96NX5|KCC1G_HUMAN
Calcium/calmodulin-dependent protein kinase type 1G
Search

CAMK1G

0.97	Calcium/calmodulin-dependent protein kinase IGa

0.63	GO:0006468	protein phosphorylation
0.49	GO:0018210	peptidyl-threonine modification
0.48	GO:0018209	peptidyl-serine modification
0.42	GO:0045475	locomotor rhythm
0.41	GO:0035556	intracellular signal transduction
0.37	GO:0060267	positive regulation of respiratory burst
0.37	GO:0090023	positive regulation of neutrophil chemotaxis
0.37	GO:0032793	positive regulation of CREB transcription factor activity
0.37	GO:0050766	positive regulation of phagocytosis
0.36	GO:0050773	regulation of dendrite development

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005516	calmodulin binding

0.61	GO:0005954	calcium- and calmodulin-dependent protein kinase complex
0.48	GO:0012505	endomembrane system
0.42	GO:0005886	plasma membrane
0.37	GO:0043005	neuron projection
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

sp|Q96NX9|DACH2_HUMAN
Dachshund homolog 2
Search

DACH2

0.96	Dachshund b

0.79	GO:0046545	development of primary female sexual characteristics
0.70	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly
0.52	GO:0048839	inner ear development
0.50	GO:1903506	regulation of nucleic acid-templated transcription
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.45	GO:0060244	negative regulation of cell proliferation involved in contact inhibition
0.45	GO:0031018	endocrine pancreas development
0.44	GO:0048147	negative regulation of fibroblast proliferation
0.44	GO:0007585	respiratory gaseous exchange

0.73	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.43	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0003677	DNA binding

0.63	GO:0005667	transcription factor complex
0.53	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q96NY7|CLIC6_HUMAN
Chloride intracellular channel protein 6
Search

CLIC6

0.65	Chloride intracellular channel protein 6

0.74	GO:0034765	regulation of ion transmembrane transport
0.74	GO:1902476	chloride transmembrane transport
0.45	GO:0006749	glutathione metabolic process
0.38	GO:0009913	epidermal cell differentiation
0.38	GO:0007605	sensory perception of sound
0.38	GO:0002064	epithelial cell development
0.38	GO:0007423	sensory organ development
0.38	GO:0000904	cell morphogenesis involved in differentiation
0.37	GO:0060563	neuroepithelial cell differentiation
0.37	GO:0042490	mechanoreceptor differentiation

0.74	GO:0005254	chloride channel activity
0.72	GO:0022832	voltage-gated channel activity
0.69	GO:0022839	ion gated channel activity
0.69	GO:0008381	mechanosensitive ion channel activity
0.46	GO:0004364	glutathione transferase activity
0.36	GO:0031751	D4 dopamine receptor binding
0.36	GO:0031749	D2 dopamine receptor binding
0.36	GO:0031750	D3 dopamine receptor binding
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0042803	protein homodimerization activity

0.79	GO:0034707	chloride channel complex
0.47	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.37	GO:0005856	cytoskeleton
0.37	GO:0098858	actin-based cell projection
0.36	GO:0005886	plasma membrane
0.35	GO:0030496	midbody
0.35	GO:0045177	apical part of cell
0.35	GO:0005911	cell-cell junction

0.46

EC:2.5.1.18

GO:0004364

sp|Q96NY8|NECT4_HUMAN
Nectin-4
Search

NECTIN4

0.96	Nectin cell adhesion molecule 4

0.72	GO:0007155	cell adhesion
0.68	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.68	GO:0044409	entry into host
0.64	GO:0019058	viral life cycle
0.49	GO:0008037	cell recognition
0.37	GO:0034332	adherens junction organization
0.34	GO:0006457	protein folding
0.33	GO:0009653	anatomical structure morphogenesis
0.33	GO:0032501	multicellular organismal process
0.33	GO:0030198	extracellular matrix organization

0.56	GO:0042802	identical protein binding
0.49	GO:0050839	cell adhesion molecule binding
0.46	GO:0005102	receptor binding
0.45	GO:0046983	protein dimerization activity
0.43	GO:0004872	receptor activity
0.37	GO:0104005	hijacked molecular function
0.34	GO:0051082	unfolded protein binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0008022	protein C-terminus binding
0.32	GO:0032403	protein complex binding

0.62	GO:0005913	cell-cell adherens junction
0.46	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.35	GO:0016272	prefoldin complex
0.32	GO:0031012	extracellular matrix
0.32	GO:0005918	septate junction
0.32	GO:0043202	lysosomal lumen
0.32	GO:0005796	Golgi lumen
0.32	GO:0005925	focal adhesion
0.32	GO:0005938	cell cortex

sp|Q96NY9|MUS81_HUMAN
Crossover junction endonuclease MUS81
Search

MUS81

0.83	MUS81 structure-specific endonuclease subunit

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.63	GO:0072429	response to intra-S DNA damage checkpoint signaling
0.55	GO:0006308	DNA catabolic process
0.52	GO:0000712	resolution of meiotic recombination intermediates
0.52	GO:0031573	intra-S DNA damage checkpoint
0.52	GO:0007095	mitotic G2 DNA damage checkpoint
0.51	GO:0000727	double-strand break repair via break-induced replication
0.51	GO:0031297	replication fork processing
0.37	GO:0036297	interstrand cross-link repair
0.35	GO:0010520	regulation of reciprocal meiotic recombination

0.64	GO:0048257	3'-flap endonuclease activity
0.55	GO:0003677	DNA binding
0.49	GO:0008821	crossover junction endodeoxyribonuclease activity
0.36	GO:0005515	protein binding
0.35	GO:0004672	protein kinase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0035091	phosphatidylinositol binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0097367	carbohydrate derivative binding

0.49	GO:0048476	Holliday junction resolvase complex
0.42	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.49

EC:3.1.22.4

GO:0008821

sp|Q96NZ1|FOXN4_HUMAN
Forkhead box protein N4
Search

FOXN4

0.97	Forkhead box protein N4

0.59	GO:0035881	amacrine cell differentiation
0.57	GO:0060579	ventral spinal cord interneuron fate commitment
0.57	GO:0010842	retina layer formation
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0051254	positive regulation of RNA metabolic process
0.54	GO:0010557	positive regulation of macromolecule biosynthetic process
0.54	GO:0031328	positive regulation of cellular biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0035326	enhancer binding
0.51	GO:0003682	chromatin binding
0.50	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.32	GO:0005215	transporter activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q96NZ8|WFKN1_HUMAN
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1
Search

WFIKKN2

0.97	Growth and differentiation factor-associated serum protein 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.68	GO:1900116	extracellular negative regulation of signal transduction
0.66	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.66	GO:0043392	negative regulation of DNA binding
0.65	GO:0060021	palate development
0.65	GO:0048747	muscle fiber development
0.65	GO:0032091	negative regulation of protein binding
0.62	GO:0001501	skeletal system development
0.53	GO:0007179	transforming growth factor beta receptor signaling pathway
0.37	GO:0006508	proteolysis

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.68	GO:0050431	transforming growth factor beta binding
0.68	GO:0048019	receptor antagonist activity
0.43	GO:0008191	metalloendopeptidase inhibitor activity
0.37	GO:0008233	peptidase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0090729	toxin activity
0.32	GO:0032555	purine ribonucleotide binding

0.65	GO:0005576	extracellular region
0.33	GO:0042151	nematocyst
0.31	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37

GO:0008233

sp|Q96NZ9|PRAP1_HUMAN
Proline-rich acidic protein 1
Search

PRAP1

0.97	Proline-rich acidic protein 1

0.63

GO:0005515

protein binding

0.66

GO:0005576

extracellular region

sp|Q96P09|BIRC8_HUMAN
Baculoviral IAP repeat-containing protein 8
Search

BIRC8

0.79	X-linked inhibitor of apoptosis

0.79	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process
0.71	GO:0006915	apoptotic process
0.69	GO:0070997	neuron death
0.68	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.62	GO:1902530	positive regulation of protein linear polyubiquitination
0.60	GO:0016567	protein ubiquitination
0.60	GO:0090307	mitotic spindle assembly
0.46	GO:0006974	cellular response to DNA damage stimulus
0.42	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.42	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

0.71	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.60	GO:0004842	ubiquitin-protein transferase activity
0.51	GO:0042802	identical protein binding
0.46	GO:0016874	ligase activity
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.44	GO:0002020	protease binding
0.42	GO:0019788	NEDD8 transferase activity
0.41	GO:0031624	ubiquitin conjugating enzyme binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0046872	metal ion binding

0.52	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.38	GO:0097179	protease inhibitor complex
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0035631	CD40 receptor complex
0.34	GO:0044446	intracellular organelle part
0.33	GO:0009898	cytoplasmic side of plasma membrane

0.46	EC:6	GO:0016874
0.60	KEGG:R03876	GO:0004842

sp|Q96P11|NSUN5_HUMAN
Probable 28S rRNA (cytosine-C(5))-methyltransferase
Search

NSUN5

0.93	Methyltransferase NSUN5

0.63	GO:0032259	methylation
0.46	GO:0000154	rRNA modification
0.37	GO:0044260	cellular macromolecule metabolic process
0.33	GO:0007010	cytoskeleton organization

0.63	GO:0008168	methyltransferase activity
0.59	GO:0003723	RNA binding
0.42	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0051015	actin filament binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0016874	ligase activity

0.53	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0008168

sp|Q96P15|SPB11_HUMAN
Serpin B11
Search

SERPINB11

0.83	Leukocyte elastase inhibitor A

0.60	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:0002244	hematopoietic progenitor cell differentiation
0.37	GO:0043312	neutrophil degranulation
0.35	GO:0035425	autocrine signaling
0.34	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.34	GO:0038001	paracrine signaling
0.34	GO:0043508	negative regulation of JUN kinase activity
0.34	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.34	GO:0010950	positive regulation of endopeptidase activity
0.34	GO:0030335	positive regulation of cell migration

0.62	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0002020	protease binding
0.34	GO:0104005	hijacked molecular function
0.34	GO:0004869	cysteine-type endopeptidase inhibitor activity

0.73	GO:0005615	extracellular space
0.40	GO:0031012	extracellular matrix
0.36	GO:0030141	secretory granule
0.36	GO:1903561	extracellular vesicle
0.35	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005766	primary lysosome
0.34	GO:0005775	vacuolar lumen
0.33	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

sp|Q96P16|RPR1A_HUMAN
Regulation of nuclear pre-mRNA domain-containing protein 1A
Search

RPRD1A

0.95	Regulation of nuclear pre-mRNA domain-containing protein 1A

0.85	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain
0.58	GO:0008284	positive regulation of cell proliferation
0.56	GO:0010564	regulation of cell cycle process
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0042795	snRNA transcription by RNA polymerase II

0.62	GO:0000993	RNA polymerase II core binding
0.58	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding

0.75	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.58	GO:0005813	centrosome
0.52	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q96P20|NLRP3_HUMAN
NACHT, LRR and PYD domains-containing protein 3
Search

NLRP3

0.77	NACHT LRR and PYD domain-containing protein 3

0.62	GO:0050711	negative regulation of interleukin-1 secretion
0.61	GO:0002674	negative regulation of acute inflammatory response
0.60	GO:0042345	regulation of NF-kappaB import into nucleus
0.60	GO:0032691	negative regulation of interleukin-1 beta production
0.60	GO:0050718	positive regulation of interleukin-1 beta secretion
0.60	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.59	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.59	GO:0090317	negative regulation of intracellular protein transport
0.59	GO:0042992	negative regulation of transcription factor import into nucleus
0.58	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.52	GO:0042802	identical protein binding
0.46	GO:0008134	transcription factor binding
0.43	GO:0043565	sequence-specific DNA binding
0.38	GO:0042834	peptidoglycan binding
0.33	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process

0.62	GO:0072559	NLRP3 inflammasome complex
0.42	GO:0005634	nucleus
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q96P26|5NT1B_HUMAN
Cytosolic 5'-nucleotidase 1B
Search

NT5C1B

0.93	Testicular tissue protein Li 1

0.68	GO:0016311	dephosphorylation
0.59	GO:0009117	nucleotide metabolic process
0.46	GO:0009116	nucleoside metabolic process
0.39	GO:0009128	purine nucleoside monophosphate catabolic process
0.35	GO:0072521	purine-containing compound metabolic process
0.34	GO:0017144	drug metabolic process
0.34	GO:1901565	organonitrogen compound catabolic process

0.79	GO:0008253	5'-nucleotidase activity
0.64	GO:0000287	magnesium ion binding
0.53	GO:0000166	nucleotide binding

0.49	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus

0.79

EC:3.1.3.5

GO:0008253

sp|Q96P31|FCRL3_HUMAN
Fc receptor-like protein 3
Search

0.68	Fc receptor like 2

0.52	GO:0006898	receptor-mediated endocytosis
0.46	GO:0002250	adaptive immune response
0.42	GO:0042113	B cell activation
0.39	GO:0009967	positive regulation of signal transduction
0.37	GO:0007165	signal transduction
0.30	GO:0050671	positive regulation of lymphocyte proliferation
0.30	GO:0002683	negative regulation of immune system process
0.30	GO:0051924	regulation of calcium ion transport
0.30	GO:0050776	regulation of immune response
0.30	GO:0002697	regulation of immune effector process

0.56	GO:0005044	scavenger receptor activity
0.43	GO:0015026	coreceptor activity
0.42	GO:0005515	protein binding
0.41	GO:0035591	signaling adaptor activity

0.49	GO:0009986	cell surface
0.45	GO:0070062	extracellular exosome
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q96P44|COLA1_HUMAN
Collagen alpha-1(XXI) chain
Search

COL21A1

0.93	Collagen type XXI alpha 1 chain

0.34	GO:0051609	inhibition of neurotransmitter uptake
0.33	GO:0009405	pathogenesis
0.32	GO:0006508	proteolysis

0.41	GO:0005201	extracellular matrix structural constituent
0.35	GO:0042302	structural constituent of cuticle
0.34	GO:0090729	toxin activity
0.33	GO:0004222	metalloendopeptidase activity

0.67	GO:0005581	collagen trimer
0.60	GO:0031012	extracellular matrix
0.56	GO:0005829	cytosol
0.38	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004222

sp|Q96P47|AGAP3_HUMAN
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3
Search

AGAP3

0.89	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

0.74	GO:0043547	positive regulation of GTPase activity
0.51	GO:0007165	signal transduction
0.36	GO:0015031	protein transport
0.35	GO:0034504	protein localization to nucleus
0.34	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.34	GO:0034614	cellular response to reactive oxygen species
0.34	GO:0051170	nuclear import
0.34	GO:0072594	establishment of protein localization to organelle
0.34	GO:0046907	intracellular transport

0.75	GO:0005096	GTPase activator activity
0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.38	GO:0005543	phospholipid binding
0.35	GO:0031593	polyubiquitin modification-dependent protein binding

0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0071944	cell periphery
0.30	GO:0016020	membrane

sp|Q96P48|ARAP1_HUMAN
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Search

ARAP1

0.46	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

0.75	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.56	GO:0051497	negative regulation of stress fiber assembly
0.55	GO:0051491	positive regulation of filopodium assembly
0.51	GO:0051270	regulation of cellular component movement
0.47	GO:0008360	regulation of cell shape
0.42	GO:0001921	positive regulation of receptor recycling
0.37	GO:0030037	actin filament reorganization involved in cell cycle
0.37	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.36	GO:0071560	cellular response to transforming growth factor beta stimulus

0.84	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.76	GO:0005096	GTPase activator activity
0.42	GO:0031702	type 1 angiotensin receptor binding
0.37	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.36	GO:0046872	metal ion binding
0.36	GO:0070412	R-SMAD binding
0.35	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0008134	transcription factor binding
0.34	GO:0003700	DNA binding transcription factor activity

0.48	GO:0005794	Golgi apparatus
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.38	GO:0031410	cytoplasmic vesicle
0.37	GO:0031984	organelle subcompartment
0.36	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.1.4.17

GO:0004114

sp|Q96P50|ACAP3_HUMAN
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3
Search

ACAP3

0.87	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

0.75

GO:0043547

positive regulation of GTPase activity

0.76	GO:0005096	GTPase activator activity
0.50	GO:0046872	metal ion binding

0.30

GO:0044425

membrane part

sp|Q96P53|WDFY2_HUMAN
WD repeat and FYVE domain-containing protein 2
Search

WDFY2

0.96	WD repeat and FYVE domain-containing protein 2

0.58	GO:0045600	positive regulation of fat cell differentiation
0.53	GO:0001934	positive regulation of protein phosphorylation
0.35	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway
0.35	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway

0.53	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.34	GO:0005545	1-phosphatidylinositol binding

0.55	GO:0005769	early endosome
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus

sp|Q96P56|CTSR2_HUMAN
Cation channel sperm-associated protein 2
Search

CATSPER2

0.90	Cation channel sperm-associated protein 2

0.84	GO:0030317	flagellated sperm motility
0.60	GO:0098655	cation transmembrane transport
0.55	GO:0019228	neuronal action potential
0.55	GO:0086010	membrane depolarization during action potential
0.49	GO:0006814	sodium ion transport
0.44	GO:0098660	inorganic ion transmembrane transport
0.42	GO:0009566	fertilization
0.41	GO:0007283	spermatogenesis
0.41	GO:0034765	regulation of ion transmembrane transport
0.41	GO:0030154	cell differentiation

0.81	GO:0005227	calcium activated cation channel activity
0.54	GO:0005248	voltage-gated sodium channel activity
0.41	GO:0005262	calcium channel activity
0.40	GO:0022832	voltage-gated channel activity
0.35	GO:0005515	protein binding

0.85	GO:0036128	CatSper complex
0.42	GO:0005929	cilium
0.39	GO:0097223	sperm part
0.37	GO:0032426	stereocilium tip
0.34	GO:0001518	voltage-gated sodium channel complex
0.33	GO:0097386	glial cell projection

sp|Q96P63|SPB12_HUMAN
Serpin B12
Search

SERPINB12

0.90	Serpin peptidase inhibitor, clade B, member 11 (Predicted)

0.61	GO:0010951	negative regulation of endopeptidase activity
0.55	GO:0002244	hematopoietic progenitor cell differentiation
0.39	GO:0002444	myeloid leukocyte mediated immunity
0.38	GO:0002283	neutrophil activation involved in immune response
0.38	GO:0043299	leukocyte degranulation
0.37	GO:0042177	negative regulation of protein catabolic process
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.34	GO:0033668	negative regulation by symbiont of host apoptotic process
0.34	GO:0071391	cellular response to estrogen stimulus

0.62	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0019899	enzyme binding
0.34	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process

0.72	GO:0005615	extracellular space
0.39	GO:0101003	ficolin-1-rich granule membrane
0.38	GO:1903561	extracellular vesicle
0.37	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q96P64|AGAP4_HUMAN
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4
Search

0.94	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4

0.76	GO:0043547	positive regulation of GTPase activity
0.37	GO:0007165	signal transduction

0.76	GO:0005096	GTPase activator activity
0.53	GO:0046872	metal ion binding
0.44	GO:0003924	GTPase activity
0.43	GO:0001883	purine nucleoside binding
0.43	GO:0019001	guanyl nucleotide binding
0.43	GO:0032549	ribonucleoside binding
0.39	GO:0032555	purine ribonucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005543	phospholipid binding

0.30

GO:0016020

membrane

sp|Q96P65|QRFPR_HUMAN
Pyroglutamylated RFamide peptide receptor
Search

QRFPR

0.95	Pyroglutamylated RFamide peptide receptor

0.71	GO:0007218	neuropeptide signaling pathway
0.48	GO:1901652	response to peptide
0.46	GO:0032870	cellular response to hormone stimulus
0.36	GO:0030431	sleep
0.36	GO:0007626	locomotory behavior

0.75	GO:0004983	neuropeptide Y receptor activity
0.47	GO:0042277	peptide binding

0.43	GO:0005887	integral component of plasma membrane
0.38	GO:0097730	non-motile cilium

sp|Q96P66|GP101_HUMAN
Probable G-protein coupled receptor 101
Search

GPR101

0.81	G protein-coupled receptor 101

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0019933	cAMP-mediated signaling
0.52	GO:0007267	cell-cell signaling

0.72

GO:0004930

G-protein coupled receptor activity

0.69	GO:0043235	receptor complex
0.48	GO:0005887	integral component of plasma membrane
0.38	GO:0005622	intracellular

sp|Q96P67|GPR82_HUMAN
Probable G-protein coupled receptor 82
Search

GPR82

0.87	G protein-coupled receptor 82

0.71

GO:0007186

G-protein coupled receptor signaling pathway

0.72

GO:0004930

G-protein coupled receptor activity

0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q96P68|OXGR1_HUMAN
2-oxoglutarate receptor 1
Search

OXGR1

0.97	Alpha-ketoglutarate receptor 1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0035587	purinergic receptor signaling pathway
0.50	GO:0030321	transepithelial chloride transport
0.39	GO:0050878	regulation of body fluid levels
0.39	GO:0050817	coagulation
0.39	GO:0071310	cellular response to organic substance
0.39	GO:0090075	relaxation of muscle
0.39	GO:0042060	wound healing
0.38	GO:0001775	cell activation
0.38	GO:0034097	response to cytokine

0.72	GO:0004930	G-protein coupled receptor activity
0.50	GO:0035586	purinergic receptor activity
0.49	GO:0016502	nucleotide receptor activity
0.40	GO:0001653	peptide receptor activity
0.38	GO:0004896	cytokine receptor activity
0.35	GO:0016208	AMP binding
0.34	GO:0019955	cytokine binding
0.34	GO:0001883	purine nucleoside binding
0.33	GO:0042277	peptide binding
0.32	GO:0016787	hydrolase activity

0.44	GO:0005886	plasma membrane
0.35	GO:0009986	cell surface
0.33	GO:0097225	sperm midpiece
0.33	GO:0097228	sperm principal piece
0.32	GO:0098552	side of membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.32

GO:0016787

sp|Q96P69|GPR78_HUMAN
G-protein coupled receptor 78
Search

GPR26

0.95	G-protein-coupled receptor 78

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0019933	cAMP-mediated signaling
0.50	GO:1903955	positive regulation of protein targeting to mitochondrion
0.47	GO:0031647	regulation of protein stability

0.71	GO:0004930	G-protein coupled receptor activity
0.30	GO:0005515	protein binding

0.37	GO:0005622	intracellular
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q96P70|IPO9_HUMAN
Importin-9
Search

IPO9

0.96	Importin-9 isoform A

0.67	GO:0006886	intracellular protein transport
0.48	GO:0006606	protein import into nucleus
0.35	GO:0050821	protein stabilization
0.34	GO:0042254	ribosome biogenesis
0.32	GO:0032259	methylation

0.78	GO:0008536	Ran GTPase binding
0.51	GO:0008565	protein transporter activity
0.38	GO:0042393	histone binding
0.33	GO:0046872	metal ion binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0003677	DNA binding

0.57	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.43	GO:0012505	endomembrane system
0.41	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008168

sp|Q96P71|NECA3_HUMAN
N-terminal EF-hand calcium-binding protein 3
Search

NECAB3

0.52	N-terminal EF-hand calcium-binding protein 3

0.57	GO:0042984	regulation of amyloid precursor protein biosynthetic process
0.47	GO:0009306	protein secretion
0.40	GO:0019538	protein metabolic process

0.69	GO:0005509	calcium ion binding
0.44	GO:0005515	protein binding

0.54	GO:0000137	Golgi cis cisterna
0.48	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005634	nucleus

sp|Q96P88|GNRR2_HUMAN
Putative gonadotropin-releasing hormone II receptor
Search

0.79	Gonadotropin-releasing hormone type II receptor

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0097211	cellular response to gonadotropin-releasing hormone

0.81	GO:0016500	protein-hormone receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.43	GO:0042277	peptide binding
0.34	GO:0001653	peptide receptor activity
0.33	GO:0005515	protein binding

0.40

GO:0005887

integral component of plasma membrane

sp|Q96PB1|CASD1_HUMAN
CAS1 domain-containing protein 1
Search

CASD1

0.82	N-acetylneuraminate 9-O-acetyltransferase

0.44	GO:0005975	carbohydrate metabolic process
0.34	GO:0006493	protein O-linked glycosylation
0.34	GO:0097502	mannosylation

0.61	GO:0047186	N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity
0.36	GO:0005201	extracellular matrix structural constituent
0.34	GO:0000030	mannosyltransferase activity
0.33	GO:0005515	protein binding

0.54	GO:0030173	integral component of Golgi membrane
0.36	GO:0005581	collagen trimer

0.61

EC:2.3.1.45

GO:0047186

sp|Q96PB7|NOE3_HUMAN
Noelin-3
Search

OLFM3

0.97	LOW QUALITY PROTEIN: noelin-3

0.51	GO:0007399	nervous system development
0.48	GO:0009887	animal organ morphogenesis
0.47	GO:0030154	cell differentiation
0.47	GO:0003190	atrioventricular valve formation
0.45	GO:0060485	mesenchyme development
0.45	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.44	GO:0001654	eye development
0.43	GO:0023041	neuronal signal transduction
0.41	GO:0061387	regulation of extent of cell growth
0.41	GO:0010628	positive regulation of gene expression

0.40	GO:0001540	amyloid-beta binding
0.39	GO:0005515	protein binding

0.76	GO:0032281	AMPA glutamate receptor complex
0.65	GO:0005615	extracellular space
0.62	GO:0005794	Golgi apparatus
0.45	GO:0045202	synapse
0.44	GO:0030054	cell junction
0.42	GO:0044295	axonal growth cone
0.42	GO:0043204	perikaryon
0.39	GO:0005783	endoplasmic reticulum
0.38	GO:0098590	plasma membrane region

sp|Q96PB8|LRC3B_HUMAN
Leucine-rich repeat-containing protein 3B
Search

LRRC3B

0.97	Leucine-rich repeat-containing protein 3B

0.38	GO:0046426	negative regulation of JAK-STAT cascade
0.37	GO:0006469	negative regulation of protein kinase activity
0.37	GO:0019221	cytokine-mediated signaling pathway

0.38

GO:0004860

protein kinase inhibitor activity

0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q96PC2|IP6K3_HUMAN
Inositol hexakisphosphate kinase 3
Search

IP6K3

0.51

Kinase

0.83	GO:0032958	inositol phosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.52	GO:0046488	phosphatidylinositol metabolic process
0.45	GO:0036211	protein modification process
0.42	GO:0044267	cellular protein metabolic process
0.37	GO:0030258	lipid modification
0.37	GO:0030308	negative regulation of cell growth
0.36	GO:0043065	positive regulation of apoptotic process
0.35	GO:0007227	signal transduction downstream of smoothened
0.35	GO:0045880	positive regulation of smoothened signaling pathway

0.61

GO:0000831

inositol hexakisphosphate 6-kinase activity

0.46	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0030054	cell junction
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part

sp|Q96PC3|AP1S3_HUMAN
AP-1 complex subunit sigma-3
Search

AP1S3

0.57	AP complex subunit sigma

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.44	GO:0042051	compound eye photoreceptor development
0.42	GO:0007411	axon guidance
0.39	GO:0045176	apical protein localization
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0050690	regulation of defense response to virus by virus
0.34	GO:0006367	transcription initiation from RNA polymerase II promoter

0.69	GO:0008565	protein transporter activity
0.38	GO:0030276	clathrin binding
0.33	GO:0046872	metal ion binding

0.75	GO:0030117	membrane coat
0.43	GO:0012510	trans-Golgi network transport vesicle membrane
0.42	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0005905	clathrin-coated pit
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol
0.33	GO:0031984	organelle subcompartment
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005667	transcription factor complex
0.33	GO:0031974	membrane-enclosed lumen

sp|Q96PC5|MIA2_HUMAN
Melanoma inhibitory activity protein 2
Search

0.67	Melanoma inhibitory activity protein 2

0.73	GO:0035459	cargo loading into vesicle
0.65	GO:0042953	lipoprotein transport
0.65	GO:0006888	ER to Golgi vesicle-mediated transport
0.65	GO:0070328	triglyceride homeostasis
0.63	GO:0042632	cholesterol homeostasis
0.62	GO:0070973	protein localization to endoplasmic reticulum exit site
0.61	GO:1905097	regulation of guanyl-nucleotide exchange factor activity
0.59	GO:0032527	protein exit from endoplasmic reticulum

0.65	GO:0042954	lipoprotein transporter activity
0.43	GO:0005515	protein binding

0.72	GO:0070971	endoplasmic reticulum exit site
0.52	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96PD2|DCBD2_HUMAN
Discoidin, CUB and LCCL domain-containing protein 2
Search

DCBLD2

0.97	Discoidin, CUB and LCCL domain-containing protein 2

0.59	GO:0030308	negative regulation of cell growth
0.59	GO:0042060	wound healing
0.42	GO:0034109	homotypic cell-cell adhesion
0.41	GO:0007599	hemostasis
0.41	GO:0050817	coagulation
0.41	GO:0001775	cell activation
0.36	GO:0030522	intracellular receptor signaling pathway

0.34

GO:0005515

protein binding

0.55	GO:0009986	cell surface
0.50	GO:0005887	integral component of plasma membrane

sp|Q96PD4|IL17F_HUMAN
Interleukin-17F
Search

IL17F

0.96	Interleukin 17

0.80	GO:0006954	inflammatory response
0.76	GO:0010469	regulation of receptor activity
0.65	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.64	GO:2000778	positive regulation of interleukin-6 secretion
0.61	GO:0032641	lymphotoxin A production
0.60	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
0.58	GO:0045414	regulation of interleukin-8 biosynthetic process
0.58	GO:0042089	cytokine biosynthetic process
0.58	GO:0045076	regulation of interleukin-2 biosynthetic process
0.57	GO:0045408	regulation of interleukin-6 biosynthetic process

0.81	GO:0005125	cytokine activity
0.55	GO:0019955	cytokine binding
0.53	GO:0005126	cytokine receptor binding
0.51	GO:0042803	protein homodimerization activity
0.34	GO:0004386	helicase activity
0.33	GO:0008233	peptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.47	GO:0009897	external side of plasma membrane
0.34	GO:0042555	MCM complex
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005813	centrosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.33

GO:0008233

sp|Q96PD5|PGRP2_HUMAN
N-acetylmuramoyl-L-alanine amidase
Search

PGLYRP2

0.37	N-acetylmuramoyl-L-alanine amidase

0.74	GO:0009253	peptidoglycan catabolic process
0.63	GO:0032824	negative regulation of natural killer cell differentiation
0.63	GO:0032826	regulation of natural killer cell differentiation involved in immune response
0.61	GO:0044117	growth of symbiont in host
0.61	GO:0016045	detection of bacterium
0.60	GO:0032689	negative regulation of interferon-gamma production
0.59	GO:0050830	defense response to Gram-positive bacterium
0.58	GO:0002221	pattern recognition receptor signaling pathway
0.57	GO:0002698	negative regulation of immune effector process
0.57	GO:0050727	regulation of inflammatory response

0.75	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.64	GO:0016019	peptidoglycan receptor activity
0.63	GO:0008270	zinc ion binding
0.56	GO:0042834	peptidoglycan binding
0.38	GO:0005096	GTPase activator activity
0.32	GO:0003676	nucleic acid binding

0.40	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.75

EC:3.5.1.28

GO:0008745

sp|Q96PD6|MOGT1_HUMAN
2-acylglycerol O-acyltransferase 1
Search

MOGAT1

0.97	Monoacylglycerol O-acyltransferase 1

0.56	GO:0006651	diacylglycerol biosynthetic process
0.42	GO:0019432	triglyceride biosynthetic process
0.41	GO:0001878	response to yeast
0.40	GO:0006071	glycerol metabolic process
0.36	GO:0050892	intestinal absorption
0.33	GO:0016310	phosphorylation

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0016301	kinase activity
0.33	GO:0048037	cofactor binding
0.32	GO:0046906	tetrapyrrole binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.64

GO:0016747

sp|Q96PD7|DGAT2_HUMAN
Diacylglycerol O-acyltransferase 2
Search

DGAT2

0.95	Diacylglycerol O-acyltransferase 2

0.60	GO:0071400	cellular response to oleic acid
0.59	GO:0060613	fat pad development
0.59	GO:0035356	cellular triglyceride homeostasis
0.59	GO:0034383	low-density lipoprotein particle clearance
0.58	GO:0055089	fatty acid homeostasis
0.58	GO:0046339	diacylglycerol metabolic process
0.57	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.56	GO:0042632	cholesterol homeostasis
0.56	GO:0019432	triglyceride biosynthetic process
0.55	GO:0019915	lipid storage

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.51	GO:0042803	protein homodimerization activity

0.55	GO:0005811	lipid droplet
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0030176	integral component of endoplasmic reticulum membrane
0.44	GO:0005739	mitochondrion

0.64

GO:0016747

sp|Q96PE1|AGRA2_HUMAN
Adhesion G protein-coupled receptor A2
Search

ADGRA2

0.84	Adhesion G protein-coupled receptor A2

0.76	GO:0090210	regulation of establishment of blood-brain barrier
0.74	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.73	GO:0002040	sprouting angiogenesis
0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0043542	endothelial cell migration
0.69	GO:0010595	positive regulation of endothelial cell migration
0.67	GO:0045765	regulation of angiogenesis
0.66	GO:0050920	regulation of chemotaxis
0.64	GO:0007417	central nervous system development

0.72	GO:0004930	G-protein coupled receptor activity
0.37	GO:0005515	protein binding

0.66	GO:0009986	cell surface
0.45	GO:0098552	side of membrane
0.43	GO:0030175	filopodium
0.41	GO:0044459	plasma membrane part
0.30	GO:0016021	integral component of membrane

sp|Q96PE2|ARHGH_HUMAN
Rho guanine nucleotide exchange factor 17
Search

ARHGEF17

0.84	Rho guanine nucleotide exchange factor 17

0.77	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.56	GO:0030036	actin cytoskeleton organization
0.37	GO:0043065	positive regulation of apoptotic process
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0035556	intracellular signal transduction

0.77

GO:0005089

Rho guanyl-nucleotide exchange factor activity

0.35	GO:0005829	cytosol
0.30	GO:0044425	membrane part

sp|Q96PE3|INP4A_HUMAN
Type I inositol 3,4-bisphosphate 4-phosphatase
Search

INPP4A

0.93	Inositol polyphosphate-4-phosphatase type I Ab

0.74	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.55	GO:0007165	signal transduction
0.43	GO:0043647	inositol phosphate metabolic process
0.41	GO:0016311	dephosphorylation

0.82	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity
0.49	GO:0052828	inositol-3,4-bisphosphate 4-phosphatase activity
0.49	GO:0017161	inositol-1,3,4-trisphosphate 4-phosphatase activity
0.46	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
0.39	GO:0005515	protein binding

0.45	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:3.1.3.66

GO:0016316

sp|Q96PE5|OPALI_HUMAN
Opalin
Search

OPALIN

0.97	Oligodendrocytic myelin paranodal and inner loop protein

0.75	GO:0044291	cell-cell contact zone
0.64	GO:0005794	Golgi apparatus
0.51	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q96PE6|ZIM3_HUMAN
Zinc finger imprinted 3
Search

0.78	RB associated KRAB zinc finger

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0006351	transcription, DNA-templated
0.35	GO:0060669	embryonic placenta morphogenesis
0.34	GO:0034249	negative regulation of cellular amide metabolic process
0.33	GO:0032269	negative regulation of cellular protein metabolic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0003700	DNA binding transcription factor activity
0.34	GO:0030371	translation repressor activity
0.34	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.35	GO:0012505	endomembrane system
0.35	GO:0044422	organelle part
0.34	GO:0031975	envelope
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0017053	transcriptional repressor complex
0.33	GO:0005615	extracellular space
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q96PE7|MCEE_HUMAN
Methylmalonyl-CoA epimerase, mitochondrial
Search

MCEE

0.49	Methylmalonyl-CoA epimerase mitochondrial

0.85	GO:0046491	L-methylmalonyl-CoA metabolic process
0.39	GO:0019626	short-chain fatty acid catabolic process
0.37	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.35	GO:0055114	oxidation-reduction process
0.35	GO:0006468	protein phosphorylation

0.84	GO:0004493	methylmalonyl-CoA epimerase activity
0.39	GO:0051213	dioxygenase activity
0.37	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0004672	protein kinase activity
0.34	GO:0016829	lyase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:5.1.99.1	GO:0004493
0.84	KEGG:R02765	GO:0004493

sp|Q96PF1|TGM7_HUMAN
Protein-glutamine gamma-glutamyltransferase Z
Search

0.95	Transglutaminase Z

0.84	GO:0018149	peptide cross-linking
0.45	GO:0030216	keratinocyte differentiation
0.43	GO:0051262	protein tetramerization
0.42	GO:0043163	cell envelope organization
0.34	GO:0031069	hair follicle morphogenesis
0.34	GO:0032259	methylation
0.33	GO:0012501	programmed cell death

0.84	GO:0003810	protein-glutamine gamma-glutamyltransferase activity
0.41	GO:0005509	calcium ion binding
0.34	GO:0008168	methyltransferase activity

0.43	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.3.2.13

GO:0003810

sp|Q96PF2|TSSK2_HUMAN
Testis-specific serine/threonine-protein kinase 2
Search

TSSK2

0.96	LOW QUALITY PROTEIN: testis-specific serine/threonine-protein kinase 1

0.63	GO:0006468	protein phosphorylation
0.57	GO:0007286	spermatid development
0.44	GO:0035556	intracellular signal transduction
0.37	GO:0007275	multicellular organism development
0.34	GO:0043066	negative regulation of apoptotic process
0.32	GO:0032870	cellular response to hormone stimulus
0.32	GO:0006508	proteolysis

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0000287	magnesium ion binding
0.36	GO:0005515	protein binding
0.32	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity

0.54	GO:0001669	acrosomal vesicle
0.52	GO:0005814	centriole
0.45	GO:0031514	motile cilium
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

sp|Q96PG1|M4A4E_HUMAN
Putative membrane-spanning 4-domains subfamily A member 4E
Search

MS4A4E

0.85	Membrane spanning 4-domains A4E

0.37

GO:0015889

cobalamin transport

0.36

GO:0031419

cobalamin binding

0.30

GO:0044425

membrane part

sp|Q96PG2|M4A10_HUMAN
Membrane-spanning 4-domains subfamily A member 10
Search

MS4A10

0.97	Membrane spanning 4-domains A10

0.30

GO:0044425

membrane part

sp|Q96PG8|BBC3B_HUMAN
Bcl-2-binding component 3
Search

BBC3

0.84	Bcl-2-binding component 3

0.86	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.84	GO:0097193	intrinsic apoptotic signaling pathway

0.57

GO:0051117

ATPase binding

0.61	GO:0005739	mitochondrion
0.54	GO:0005764	lysosome

sp|Q96PH1|NOX5_HUMAN
NADPH oxidase 5
Search

NOX5

0.94	NADPH oxidase, EF-hand calcium binding domain 5

0.85	GO:0042554	superoxide anion generation
0.60	GO:0001935	endothelial cell proliferation
0.53	GO:0055114	oxidation-reduction process
0.47	GO:1902600	hydrogen ion transmembrane transport
0.46	GO:1990266	neutrophil migration
0.44	GO:0030728	ovulation
0.43	GO:0045987	positive regulation of smooth muscle contraction
0.43	GO:0050850	positive regulation of calcium-mediated signaling
0.39	GO:0043012	regulation of fusion of sperm to egg plasma membrane
0.38	GO:0010155	regulation of proton transport

0.85	GO:0016175	superoxide-generating NADPH oxidase activity
0.68	GO:0005509	calcium ion binding
0.60	GO:0015252	proton channel activity
0.35	GO:0050661	NADP binding
0.35	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0020037	heme binding
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.36	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.85

EC:1.6.3

GO:0016175

sp|Q96PH6|DB118_HUMAN
Beta-defensin 118
Search

DEFB118

0.64	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium
0.74	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.67	GO:0031640	killing of cells of other organism
0.64	GO:0051673	membrane disruption in other organism
0.48	GO:0007160	cell-matrix adhesion
0.48	GO:0007283	spermatogenesis

0.66	GO:0005576	extracellular region
0.53	GO:0009986	cell surface

sp|Q96PI1|SPRR4_HUMAN
Small proline-rich protein 4
Search

0.94	Small proline-rich protein 4

0.74	GO:0018149	peptide cross-linking
0.63	GO:0030216	keratinocyte differentiation
0.41	GO:0032355	response to estradiol
0.40	GO:0012501	programmed cell death
0.36	GO:0008585	female gonad development
0.34	GO:0009411	response to UV
0.33	GO:0051258	protein polymerization
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0008360	regulation of cell shape

0.49	GO:0005198	structural molecule activity
0.43	GO:0030674	protein binding, bridging
0.33	GO:0046983	protein dimerization activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.76	GO:0001533	cornified envelope
0.45	GO:0005737	cytoplasm
0.37	GO:0043227	membrane-bounded organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.36	GO:0012505	endomembrane system
0.35	GO:0043229	intracellular organelle

sp|Q96PJ5|FCRL4_HUMAN
Fc receptor-like protein 4
Search

FCRL4

0.91	Fc receptor like 4

0.47	GO:0050859	negative regulation of B cell receptor signaling pathway
0.46	GO:0034163	regulation of toll-like receptor 9 signaling pathway
0.46	GO:0009967	positive regulation of signal transduction
0.46	GO:0002638	negative regulation of immunoglobulin production
0.45	GO:0045577	regulation of B cell differentiation
0.45	GO:0030890	positive regulation of B cell proliferation
0.45	GO:0090279	regulation of calcium ion import
0.43	GO:0043408	regulation of MAPK cascade
0.42	GO:0001934	positive regulation of protein phosphorylation
0.42	GO:0006898	receptor-mediated endocytosis

0.45	GO:0005044	scavenger receptor activity
0.44	GO:0019902	phosphatase binding
0.44	GO:0005070	SH3/SH2 adaptor activity
0.43	GO:0019900	kinase binding
0.37	GO:0015026	coreceptor activity

0.60	GO:0009986	cell surface
0.43	GO:0043235	receptor complex
0.38	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q96PK6|RBM14_HUMAN
RNA-binding protein 14
Search

RBM14

0.97	RNA binding motif protein 14

0.65	GO:0098534	centriole assembly
0.65	GO:0046600	negative regulation of centriole replication
0.63	GO:0060395	SMAD protein signal transduction
0.61	GO:0002218	activation of innate immune response
0.60	GO:0016575	histone deacetylation
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0045087	innate immune response
0.41	GO:0032055	negative regulation of translation in response to stress
0.41	GO:0110017	cap-independent translational initiation of linear mRNA
0.40	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.63	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.58	GO:0003723	RNA binding
0.41	GO:0008270	zinc ion binding
0.39	GO:0030332	cyclin binding
0.37	GO:0030674	protein binding, bridging
0.36	GO:0001104	RNA polymerase II transcription cofactor activity

0.61	GO:0016607	nuclear speck
0.57	GO:0005667	transcription factor complex
0.44	GO:0005730	nucleolus
0.42	GO:0005737	cytoplasm
0.38	GO:0035770	ribonucleoprotein granule
0.36	GO:0016592	mediator complex

sp|Q96PL1|SG3A2_HUMAN
Secretoglobin family 3A member 2
Search

SCGB3A2

0.97	Secretoglobin family 3A member 2

0.41

GO:0006898

receptor-mediated endocytosis

0.38

GO:0005515

protein binding

0.66	GO:0005576	extracellular region
0.47	GO:0071682	endocytic vesicle lumen

sp|Q96PL2|TECTB_HUMAN
Beta-tectorin
Search

TECTB

0.97	Beta-tectorin

0.37	GO:0048840	otolith development
0.37	GO:0006501	C-terminal protein lipidation
0.36	GO:0007605	sensory perception of sound

0.61	GO:0005201	extracellular matrix structural constituent
0.34	GO:0016874	ligase activity

0.65	GO:0005576	extracellular region
0.39	GO:0031225	anchored component of membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0016874

sp|Q96PL5|ERMAP_HUMAN
Erythroid membrane-associated protein
Search

ERMAP

0.79	Erythroblast membrane-associated protein (Scianna blood group)

0.42	GO:0016567	protein ubiquitination
0.40	GO:0034341	response to interferon-gamma
0.39	GO:0010508	positive regulation of autophagy
0.39	GO:0001817	regulation of cytokine production
0.39	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly
0.39	GO:0044093	positive regulation of molecular function
0.38	GO:1903901	negative regulation of viral life cycle
0.38	GO:0030162	regulation of proteolysis
0.38	GO:0070206	protein trimerization
0.38	GO:0046598	positive regulation of viral entry into host cell

0.48	GO:0008270	zinc ion binding
0.42	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0016874	ligase activity
0.38	GO:0042802	identical protein binding
0.37	GO:0061659	ubiquitin-like protein ligase activity
0.36	GO:0050681	androgen receptor binding
0.36	GO:0035035	histone acetyltransferase binding
0.36	GO:0003779	actin binding
0.35	GO:1990782	protein tyrosine kinase binding
0.34	GO:0030674	protein binding, bridging

0.39	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0044422	organelle part
0.35	GO:0043228	non-membrane-bounded organelle
0.35	GO:1990234	transferase complex
0.35	GO:0005615	extracellular space
0.34	GO:0043234	protein complex
0.34	GO:0012505	endomembrane system

0.40	EC:6	GO:0016874
0.42	KEGG:R03876	GO:0004842

sp|Q96PM5|ZN363_HUMAN
RING finger and CHY zinc finger domain-containing protein 1
Search

RCHY1

0.50	RING finger and CHY zinc finger domain-containing protein 1

0.53	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.51	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.51	GO:0031398	positive regulation of protein ubiquitination
0.38	GO:0051865	protein autoubiquitination
0.35	GO:0070987	error-free translesion synthesis
0.32	GO:0006468	protein phosphorylation
0.31	GO:0043043	peptide biosynthetic process
0.31	GO:0010467	gene expression

0.61	GO:0008270	zinc ion binding
0.53	GO:0002039	p53 binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0005102	receptor binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0005524	ATP binding
0.32	GO:0003735	structural constituent of ribosome

0.49	GO:0000151	ubiquitin ligase complex
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.31	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.48

GO:0004842

sp|Q96PM9|Z385A_HUMAN
Zinc finger protein 385A
Search

ZNF385A

0.52	Zinc finger domain-containing protein (Fragment)

0.65	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression
0.64	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.64	GO:0070889	platelet alpha granule organization
0.62	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.61	GO:0035855	megakaryocyte development
0.61	GO:0030220	platelet formation
0.60	GO:0045600	positive regulation of fat cell differentiation
0.59	GO:2000765	regulation of cytoplasmic translation
0.57	GO:0007611	learning or memory
0.57	GO:0007599	hemostasis

0.62	GO:0008270	zinc ion binding
0.61	GO:0002039	p53 binding
0.59	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.34	GO:0035257	nuclear hormone receptor binding
0.33	GO:0003677	DNA binding

0.58	GO:0043025	neuronal cell body
0.56	GO:0030425	dendrite
0.53	GO:0000790	nuclear chromatin
0.38	GO:0005730	nucleolus
0.36	GO:0008305	integrin complex
0.35	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm

sp|Q96PN6|ADCYA_HUMAN
Adenylate cyclase type 10
Search

ADCY10

0.80	Adenylate cyclase type 10

0.75	GO:0009190	cyclic nucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.56	GO:0003351	epithelial cilium movement
0.54	GO:0071241	cellular response to inorganic substance
0.53	GO:0046058	cAMP metabolic process
0.47	GO:0009152	purine ribonucleotide biosynthetic process
0.45	GO:0007283	spermatogenesis
0.32	GO:0055114	oxidation-reduction process
0.30	GO:0010942	positive regulation of cell death
0.30	GO:0042981	regulation of apoptotic process

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.60	GO:0071890	bicarbonate binding
0.52	GO:0009975	cyclase activity
0.40	GO:0000287	magnesium ion binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016722	oxidoreductase activity, oxidizing metal ions
0.30	GO:0051117	ATPase binding
0.30	GO:0046914	transition metal ion binding

0.52	GO:0031514	motile cilium
0.52	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0015630	microtubule cytoskeleton
0.44	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane
0.30	GO:0045177	apical part of cell
0.30	GO:0044463	cell projection part
0.30	GO:0097447	dendritic tree
0.30	GO:0043025	neuronal cell body
0.30	GO:0030427	site of polarized growth

0.75

EC:4.6

GO:0016849

sp|Q96PN7|TREF1_HUMAN
Transcriptional-regulating factor 1
Search

TRERF1

0.97	Transcriptional-regulating factor 1

0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0006707	cholesterol catabolic process
0.38	GO:0046885	regulation of hormone biosynthetic process
0.36	GO:0006694	steroid biosynthetic process
0.35	GO:0007275	multicellular organism development
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0042592	homeostatic process

0.54	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0008134	transcription factor binding
0.42	GO:0003700	DNA binding transcription factor activity
0.37	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.36	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0046872	metal ion binding

0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.47	GO:0005667	transcription factor complex
0.46	GO:0044446	intracellular organelle part
0.42	GO:1902494	catalytic complex

sp|Q96PN8|TSSK3_HUMAN
Testis-specific serine/threonine-protein kinase 3
Search

TSSK3

0.94	Testis-specific serine/threonine-protein kinase 3

0.63	GO:0006468	protein phosphorylation
0.61	GO:0007283	spermatogenesis
0.49	GO:0007281	germ cell development
0.43	GO:0035556	intracellular signal transduction
0.42	GO:0006997	nucleus organization
0.40	GO:0006323	DNA packaging
0.40	GO:0006325	chromatin organization
0.37	GO:0007275	multicellular organism development
0.35	GO:0030010	establishment of cell polarity
0.35	GO:0048469	cell maturation

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0000287	magnesium ion binding
0.36	GO:0005515	protein binding
0.35	GO:0060089	molecular transducer activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.46	GO:0001669	acrosomal vesicle
0.45	GO:0005814	centriole
0.43	GO:0005634	nucleus
0.36	GO:0005964	phosphorylase kinase complex
0.36	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7.6

GO:0003899

sp|Q96PP4|TSG13_HUMAN
Testis-specific gene 13 protein
Search

TSGA13

0.97	Testis specific 13

0.85

GO:1903955

positive regulation of protein targeting to mitochondrion

sp|Q96PP8|GBP5_HUMAN
Guanylate-binding protein 5
Search

0.93	Interferon-induced guanylate-binding protein 1

0.48	GO:0050702	interleukin-1 beta secretion
0.48	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly
0.46	GO:0051260	protein homooligomerization
0.46	GO:0071346	cellular response to interferon-gamma
0.45	GO:0051262	protein tetramerization
0.44	GO:0072616	interleukin-18 secretion
0.44	GO:0001817	regulation of cytokine production
0.42	GO:0050776	regulation of immune response
0.41	GO:0050729	positive regulation of inflammatory response
0.41	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042802	identical protein binding
0.41	GO:0051879	Hsp90 protein binding
0.40	GO:0030507	spectrin binding
0.40	GO:0019955	cytokine binding
0.38	GO:0003779	actin binding
0.38	GO:0019899	enzyme binding

0.41	GO:0031410	cytoplasmic vesicle
0.41	GO:0005829	cytosol
0.41	GO:0000139	Golgi membrane
0.40	GO:0020005	symbiont-containing vacuole membrane
0.40	GO:0015629	actin cytoskeleton
0.39	GO:0005654	nucleoplasm
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q96PP9|GBP4_HUMAN
Guanylate-binding protein 4
Search

0.88	Guanylate binding protein 4

0.47	GO:0071346	cellular response to interferon-gamma
0.46	GO:0032687	negative regulation of interferon-alpha production
0.44	GO:0042308	negative regulation of protein import into nucleus
0.44	GO:0050688	regulation of defense response to virus
0.44	GO:0031397	negative regulation of protein ubiquitination
0.42	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0001933	negative regulation of protein phosphorylation
0.41	GO:0035458	cellular response to interferon-beta
0.41	GO:0042832	defense response to protozoan
0.40	GO:0050830	defense response to Gram-positive bacterium

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005515	protein binding

0.42	GO:0020005	symbiont-containing vacuole membrane
0.38	GO:0031410	cytoplasmic vesicle

sp|Q96PQ0|SORC2_HUMAN
VPS10 domain-containing receptor SorCS2
Search

SORCS2

0.71

Sortilin

0.36

GO:0007218

neuropeptide signaling pathway

0.36	GO:0008188	neuropeptide receptor activity
0.34	GO:0005515	protein binding

0.36	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

sp|Q96PQ1|SIG12_HUMAN
Sialic acid-binding Ig-like lectin 12
Search

0.96	Sialic acid binding Ig like lectin 8

0.42	GO:0007155	cell adhesion
0.39	GO:0060101	negative regulation of phagocytosis, engulfment
0.38	GO:0048583	regulation of response to stimulus
0.38	GO:0043312	neutrophil degranulation
0.37	GO:0023052	signaling
0.37	GO:0002682	regulation of immune system process
0.37	GO:0007154	cell communication
0.36	GO:0051716	cellular response to stimulus
0.34	GO:0008285	negative regulation of cell proliferation

0.51	GO:0030246	carbohydrate binding
0.38	GO:0033691	sialic acid binding
0.38	GO:0004872	receptor activity
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0005515	protein binding

0.44	GO:0009897	external side of plasma membrane
0.38	GO:0005634	nucleus
0.37	GO:0030667	secretory granule membrane
0.37	GO:0005887	integral component of plasma membrane
0.35	GO:0070820	tertiary granule
0.35	GO:0042581	specific granule
0.35	GO:0005576	extracellular region

sp|Q96PQ5|IPP2L_HUMAN
Putative protein phosphatase inhibitor 2-like protein 1
Search

PPP1R2

0.89	Cardiac inhibitor-2

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.70	GO:0009966	regulation of signal transduction
0.41	GO:0005977	glycogen metabolic process
0.35	GO:0032091	negative regulation of protein binding
0.35	GO:0006470	protein dephosphorylation
0.34	GO:0007568	aging
0.33	GO:0006869	lipid transport

0.83	GO:0004864	protein phosphatase inhibitor activity
0.36	GO:0005515	protein binding
0.35	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0031409	pigment binding
0.33	GO:0008289	lipid binding

0.51	GO:0000164	protein phosphatase type 1 complex
0.36	GO:0098723	skeletal muscle myofibril
0.35	GO:0043197	dendritic spine
0.35	GO:0030426	growth cone
0.30	GO:0016020	membrane

0.35

EC:3.1.3.16

GO:0004721

sp|Q96PQ6|ZN317_HUMAN
Zinc finger protein 317
Search

0.40	Zinc finger protein 317

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.35	GO:0072562	blood microparticle

sp|Q96PQ7|KLHL5_HUMAN
Kelch-like protein 5
Search

KLHL5

0.90	Kelch like family member 5

0.67

GO:0016567

protein ubiquitination

0.68

GO:0004842

ubiquitin-protein transferase activity

0.76	GO:0031463	Cul3-RING ubiquitin ligase complex
0.51	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004842

sp|Q96PR1|KCNC2_HUMAN
Potassium voltage-gated channel subfamily C member 2
Search

KCNC2

0.89	LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily C member 2

0.72	GO:0071805	potassium ion transmembrane transport
0.71	GO:0051260	protein homooligomerization
0.71	GO:0034765	regulation of ion transmembrane transport
0.48	GO:0046928	regulation of neurotransmitter secretion
0.45	GO:0038060	nitric oxide-cGMP-mediated signaling pathway
0.44	GO:0021759	globus pallidus development
0.43	GO:0071732	cellular response to nitric oxide
0.42	GO:1990089	response to nerve growth factor
0.42	GO:0014075	response to amine
0.42	GO:0051291	protein heterooligomerization

0.76	GO:0005249	voltage-gated potassium channel activity
0.45	GO:0044325	ion channel binding
0.39	GO:0019894	kinesin binding

0.77	GO:0008076	voltage-gated potassium channel complex
0.50	GO:0043679	axon terminus
0.48	GO:0031594	neuromuscular junction
0.46	GO:0032809	neuronal cell body membrane
0.45	GO:0030673	axolemma
0.44	GO:0030425	dendrite
0.42	GO:0043204	perikaryon
0.41	GO:0016323	basolateral plasma membrane
0.41	GO:0016324	apical plasma membrane
0.40	GO:0042734	presynaptic membrane

sp|Q96PS1|FACOS_HUMAN
FANCD2 opposite strand protein
Search

tr|Q96PS2|Q96PS2_HUMAN
FGF-2 activity-associated protein 3
Search

0.56	FGF-2 activity-associated protein 3

sp|Q96PS6|GAFA1_HUMAN
Putative uncharacterized protein GAFA-1
Search

sp|Q96PS8|AQP10_HUMAN
Aquaporin-10
Search

0.54	LOW QUALITY PROTEIN: aquaporin-10

0.68	GO:0006833	water transport
0.55	GO:0055085	transmembrane transport
0.49	GO:0015793	glycerol transport
0.47	GO:0015840	urea transport
0.46	GO:0009636	response to toxic substance
0.41	GO:0015700	arsenite transport
0.40	GO:0006863	purine nucleobase transport
0.40	GO:0071320	cellular response to cAMP
0.39	GO:0015837	amine transport
0.38	GO:0046689	response to mercury ion

0.69	GO:0022803	passive transmembrane transporter activity
0.50	GO:0015168	glycerol transmembrane transporter activity
0.49	GO:0005372	water transmembrane transporter activity
0.47	GO:0015204	urea transmembrane transporter activity
0.41	GO:0015105	arsenite transmembrane transporter activity
0.40	GO:0005345	purine nucleobase transmembrane transporter activity
0.38	GO:0005350	pyrimidine nucleobase transmembrane transporter activity
0.37	GO:0004012	phospholipid-translocating ATPase activity
0.35	GO:0000287	magnesium ion binding
0.34	GO:0032559	adenyl ribonucleotide binding

0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37

EC:3.6.3.1

GO:0004012

sp|Q96PT3|DUX5_HUMAN
Double homeobox protein 5
Search

0.92	Double homeobox protein 5

0.46	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0009790	embryo development
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process
0.40	GO:0009888	tissue development
0.40	GO:0048646	anatomical structure formation involved in morphogenesis
0.40	GO:0006351	transcription, DNA-templated

0.55	GO:0003677	DNA binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0005515	protein binding
0.32	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.38	GO:0005794	Golgi apparatus
0.37	GO:0043233	organelle lumen
0.37	GO:0005829	cytosol
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.33	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004725

sp|Q96PT4|DUX3_HUMAN
Putative double homeobox protein 3
Search

0.91	Double homeobox protein 5

0.46	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.41	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0010557	positive regulation of macromolecule biosynthetic process
0.41	GO:0031328	positive regulation of cellular biosynthetic process
0.41	GO:0009790	embryo development
0.40	GO:0009888	tissue development
0.40	GO:0048646	anatomical structure formation involved in morphogenesis
0.40	GO:0006351	transcription, DNA-templated

0.55	GO:0003677	DNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.32	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.38	GO:0005794	Golgi apparatus
0.38	GO:0043233	organelle lumen
0.38	GO:0005829	cytosol
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.33	GO:0005667	transcription factor complex

0.32

GO:0004725

sp|Q96PU4|UHRF2_HUMAN
E3 ubiquitin-protein ligase UHRF2
Search

UHRF2

0.94	Ubiquitin like with PHD and ring finger domains 2

0.73	GO:0071158	positive regulation of cell cycle arrest
0.73	GO:0051865	protein autoubiquitination
0.67	GO:0008283	cell proliferation
0.63	GO:0010216	maintenance of DNA methylation
0.62	GO:0090308	regulation of methylation-dependent chromatin silencing
0.61	GO:0030154	cell differentiation
0.39	GO:0010390	histone monoubiquitination
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II

0.67	GO:0061630	ubiquitin protein ligase activity
0.63	GO:0042393	histone binding
0.54	GO:0046872	metal ion binding
0.40	GO:0044729	hemi-methylated DNA-binding
0.39	GO:0140034	methylation-dependent protein binding
0.39	GO:0031491	nucleosome binding
0.37	GO:0042802	identical protein binding

0.70	GO:0005720	nuclear heterochromatin
0.60	GO:0005654	nucleoplasm
0.39	GO:0016363	nuclear matrix
0.37	GO:0005657	replication fork

sp|Q96PU5|NED4L_HUMAN
E3 ubiquitin-protein ligase NEDD4-like
Search

NEDD4L

0.81	Neural precursor cell-expressed, developmentally down-regulated 4-like

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination
0.67	GO:2000650	negative regulation of sodium ion transmembrane transporter activity
0.66	GO:2000009	negative regulation of protein localization to cell surface
0.66	GO:1901017	negative regulation of potassium ion transmembrane transporter activity
0.65	GO:1903861	positive regulation of dendrite extension
0.65	GO:0060306	regulation of membrane repolarization
0.65	GO:0003254	regulation of membrane depolarization
0.58	GO:0010038	response to metal ion
0.58	GO:0010498	proteasomal protein catabolic process

0.75	GO:0061630	ubiquitin protein ligase activity
0.67	GO:0019870	potassium channel inhibitor activity
0.66	GO:0019871	sodium channel inhibitor activity
0.63	GO:0044325	ion channel binding
0.38	GO:0016874	ligase activity

0.47	GO:0070062	extracellular exosome
0.45	GO:0005886	plasma membrane
0.38	GO:0005737	cytoplasm

0.38

GO:0016874

sp|Q96PU8|QKI_HUMAN
Protein quaking
Search

QKI

0.96	Quaking homolog, KH domain RNA binding

0.46	GO:0061158	3'-UTR-mediated mRNA destabilization
0.45	GO:0030154	cell differentiation
0.45	GO:0042759	long-chain fatty acid biosynthetic process
0.45	GO:0007275	multicellular organism development
0.44	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.43	GO:0007283	spermatogenesis
0.43	GO:0061061	muscle structure development
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.42	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.46	GO:0017124	SH3 domain binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

sp|Q96PU9|ODF3A_HUMAN
Outer dense fiber protein 3
Search

0.86	Outer dense fiber of sperm tails 3

0.43	GO:0007165	signal transduction
0.41	GO:0010469	regulation of receptor activity
0.40	GO:0015074	DNA integration
0.39	GO:0006310	DNA recombination
0.30	GO:0048232	male gamete generation
0.30	GO:0007275	multicellular organism development
0.30	GO:0048869	cellular developmental process

0.44	GO:0005184	neuropeptide hormone activity
0.37	GO:0003677	DNA binding

0.65	GO:0001520	outer dense fiber
0.30	GO:0016020	membrane
0.30	GO:0005737	cytoplasm

sp|Q96PV0|SYGP1_HUMAN
Ras/Rap GTPase-activating protein SynGAP
Search

SYNGAP1

0.91	Ras GTPase-activating protein SynGAP

0.75	GO:0043087	regulation of GTPase activity
0.74	GO:0046580	negative regulation of Ras protein signal transduction
0.71	GO:0051345	positive regulation of hydrolase activity
0.61	GO:0007165	signal transduction
0.59	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.58	GO:0050771	negative regulation of axonogenesis
0.58	GO:0008542	visual learning
0.57	GO:0043113	receptor clustering
0.56	GO:0043524	negative regulation of neuron apoptotic process
0.56	GO:0016358	dendrite development

0.73	GO:0005096	GTPase activator activity
0.39	GO:0017124	SH3 domain binding
0.35	GO:0019901	protein kinase binding
0.31	GO:0003676	nucleic acid binding

0.58	GO:0043198	dendritic shaft
0.56	GO:0014069	postsynaptic density
0.49	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.38	GO:0005622	intracellular
0.37	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|Q96PV4|PNMA5_HUMAN
Paraneoplastic antigen-like protein 5
Search

0.97	Paraneoplastic Ma antigen 3

0.47	GO:0002437	inflammatory response to antigenic stimulus
0.45	GO:0043065	positive regulation of apoptotic process

0.53	GO:0042802	identical protein binding
0.49	GO:0008270	zinc ion binding
0.42	GO:0003676	nucleic acid binding

0.59	GO:0005730	nucleolus
0.42	GO:0005737	cytoplasm

sp|Q96PV6|LENG8_HUMAN
Leukocyte receptor cluster member 8
Search

LENG8

0.81	Leukocyte receptor cluster member 8

0.50

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q96PV7|F193B_HUMAN
Protein FAM193B
Search

sp|Q96PW8|K1920_HUMAN
Putative uncharacterized protein KIAA1920
Search

sp|Q96PX1|RN157_HUMAN
RING finger protein 157
Search

RNF157

0.86	Ring finger protein 157

0.43	GO:0016192	vesicle-mediated transport
0.42	GO:0043951	negative regulation of cAMP-mediated signaling
0.42	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.41	GO:0032940	secretion by cell
0.41	GO:0007041	lysosomal transport
0.41	GO:0006513	protein monoubiquitination
0.41	GO:0000209	protein polyubiquitination
0.40	GO:0016197	endosomal transport
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.54	GO:0016874	ligase activity
0.45	GO:0046872	metal ion binding
0.43	GO:0016740	transferase activity
0.40	GO:0043565	sequence-specific DNA binding
0.39	GO:0003700	DNA binding transcription factor activity
0.37	GO:0005515	protein binding
0.36	GO:0140096	catalytic activity, acting on a protein

0.44	GO:0000145	exocyst
0.41	GO:0005634	nucleus
0.41	GO:0070062	extracellular exosome
0.40	GO:0005769	early endosome
0.38	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane

0.54

GO:0016874

sp|Q96PX6|CC85A_HUMAN
Coiled-coil domain-containing protein 85A
Search

CCDC85A

0.84	Coiled-coil domain-containing protein 85A

0.40

GO:0055085

transmembrane transport

0.41

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|Q96PX8|SLIK1_HUMAN
SLIT and NTRK-like protein 1
Search

SLITRK1

0.97	SLIT and NTRK like family member 1

0.59	GO:0050772	positive regulation of axonogenesis
0.58	GO:0007416	synapse assembly
0.56	GO:0051965	positive regulation of synapse assembly
0.55	GO:0035264	multicellular organism growth
0.54	GO:0030534	adult behavior
0.54	GO:0007409	axonogenesis
0.47	GO:0042592	homeostatic process

0.33

GO:0005515

protein binding

0.51	GO:0045202	synapse
0.37	GO:0030054	cell junction
0.36	GO:0005576	extracellular region
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q96PX9|PKH4B_HUMAN
Pleckstrin homology domain-containing family G member 4B
Search

PLEKHG4B

0.82	Pleckstrin homology and RhoGEF domain containing G4

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.34	GO:0048332	mesoderm morphogenesis
0.34	GO:0006885	regulation of pH
0.34	GO:0009887	animal organ morphogenesis
0.34	GO:0035725	sodium ion transmembrane transport
0.33	GO:1902600	hydrogen ion transmembrane transport

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0015385	sodium:proton antiporter activity

0.30

GO:0016020

membrane

sp|Q96PY0|K1908_HUMAN
Putative uncharacterized protein PSMG3-AS1
Search

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity

sp|Q96PY5|FMNL2_HUMAN
Formin-like protein 2
Search

FMNL2

0.85	Formin like 2

0.73	GO:0030036	actin cytoskeleton organization
0.69	GO:0022604	regulation of cell morphogenesis
0.62	GO:0030865	cortical cytoskeleton organization

0.77	GO:0017048	Rho GTPase binding
0.73	GO:0003779	actin binding
0.62	GO:0045296	cadherin binding

sp|Q96PY6|NEK1_HUMAN
Serine/threonine-protein kinase Nek1
Search

NEK1

0.80	NIMA (Never in mitosis gene a)-related kinase 1

0.66	GO:0042769	DNA damage response, detection of DNA damage
0.63	GO:0006468	protein phosphorylation
0.62	GO:0060271	cilium assembly
0.50	GO:0031098	stress-activated protein kinase signaling cascade
0.48	GO:0032147	activation of protein kinase activity
0.47	GO:0007346	regulation of mitotic cell cycle
0.47	GO:1904888	cranial skeletal system development
0.46	GO:0042981	regulation of apoptotic process
0.36	GO:2000001	regulation of DNA damage checkpoint
0.35	GO:0035264	multicellular organism growth

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0071889	14-3-3 protein binding

0.64	GO:0000242	pericentriolar material
0.48	GO:0005634	nucleus

sp|Q96PZ0|PUS7_HUMAN
Pseudouridylate synthase 7 homolog
Search

PUS7

0.94	Pseudouridylate synthase 7

0.70	GO:0001522	pseudouridine synthesis
0.35	GO:0008033	tRNA processing
0.34	GO:0048193	Golgi vesicle transport

0.71	GO:0009982	pseudouridine synthase activity
0.58	GO:0003723	RNA binding
0.49	GO:0019899	enzyme binding
0.38	GO:0004730	pseudouridylate synthase activity

0.40	GO:0005634	nucleus
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.71	EC:5.4.99.12	GO:0009982
0.38	KEGG:R01055	GO:0004730

sp|Q96PZ2|F111A_HUMAN
Protein FAM111A
Search

0.95	Peptidase cysteine/serine, trypsin-like containing protein

sp|Q96PZ7|CSMD1_HUMAN
CUB and sushi domain-containing protein 1
Search

0.55	CUB and sushi domain-containing protein 1

0.57	GO:0001964	startle response
0.54	GO:0042593	glucose homeostasis

0.30

GO:0044425

membrane part

sp|Q96Q04|LMTK3_HUMAN
Serine/threonine-protein kinase LMTK3
Search

LMTK3

0.87	Lemur tyrosine kinase 3

0.63	GO:0006468	protein phosphorylation
0.49	GO:0010923	negative regulation of phosphatase activity
0.48	GO:0033572	transferrin transport
0.48	GO:0001881	receptor recycling
0.48	GO:0045022	early endosome to late endosome transport
0.46	GO:0032456	endocytic recycling
0.46	GO:0018210	peptidyl-threonine modification
0.46	GO:0035308	negative regulation of protein dephosphorylation
0.46	GO:0018209	peptidyl-serine modification
0.45	GO:0043666	regulation of phosphoprotein phosphatase activity

0.63	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0070853	myosin VI binding
0.46	GO:0004864	protein phosphatase inhibitor activity
0.35	GO:0046872	metal ion binding
0.31	GO:0003677	DNA binding

0.46	GO:0055037	recycling endosome
0.45	GO:0005769	early endosome
0.45	GO:0005794	Golgi apparatus
0.45	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005829	cytosol
0.41	GO:0036477	somatodendritic compartment
0.40	GO:0043005	neuron projection
0.40	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment

sp|Q96Q05|TPPC9_HUMAN
Trafficking protein particle complex subunit 9
Search

TRAPPC9

0.96	LOW QUALITY PROTEIN: trafficking protein particle complex subunit 9

0.81	GO:0021987	cerebral cortex development
0.79	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.73	GO:0030182	neuron differentiation
0.41	GO:0048208	COPII vesicle coating

0.44	GO:0005515	protein binding
0.38	GO:0098772	molecular function regulator

0.78	GO:0030008	TRAPP complex
0.60	GO:0005802	trans-Golgi network
0.46	GO:0005770	late endosome
0.46	GO:0005769	early endosome
0.45	GO:0005783	endoplasmic reticulum
0.39	GO:0000139	Golgi membrane
0.38	GO:0005829	cytosol

sp|Q96Q06|PLIN4_HUMAN
Perilipin-4
Search

PLIN4

0.75	Perilipin 4

0.61	GO:0042157	lipoprotein metabolic process
0.60	GO:0006869	lipid transport
0.34	GO:0009405	pathogenesis

0.59	GO:0008289	lipid binding
0.35	GO:0045296	cadherin binding

0.73	GO:0005811	lipid droplet
0.61	GO:0005829	cytosol
0.55	GO:0005576	extracellular region
0.51	GO:0043231	intracellular membrane-bounded organelle
0.51	GO:0005886	plasma membrane
0.37	GO:0019867	outer membrane
0.34	GO:0044462	external encapsulating structure part
0.34	GO:0030313	cell envelope
0.30	GO:0044425	membrane part

sp|Q96Q07|BTBD9_HUMAN
BTB/POZ domain-containing protein 9
Search

BTBD9

0.85	BTB/POZ domain-containing protein 9

0.83	GO:0042748	circadian sleep/wake cycle, non-REM sleep
0.79	GO:1900242	regulation of synaptic vesicle endocytosis
0.79	GO:0060586	multicellular organismal iron ion homeostasis
0.77	GO:0042428	serotonin metabolic process
0.76	GO:0050951	sensory perception of temperature stimulus
0.75	GO:0007616	long-term memory
0.75	GO:0008344	adult locomotory behavior
0.53	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.53	GO:0050804	modulation of chemical synaptic transmission
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.52	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0004462	lactoylglutathione lyase activity
0.38	GO:0046872	metal ion binding

0.54	GO:0019005	SCF ubiquitin ligase complex
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.47	EC:4.4.1.5	GO:0004462
0.47	KEGG:R02530	GO:0004462

sp|Q96Q11|TRNT1_HUMAN
CCA tRNA nucleotidyltransferase 1, mitochondrial
Search

TRNT1

0.92	CCA tRNA nucleotidyltransferase 1, mitochondrial

0.63	GO:0006396	RNA processing
0.55	GO:0000959	mitochondrial RNA metabolic process
0.54	GO:0140053	mitochondrial gene expression
0.48	GO:0006399	tRNA metabolic process
0.47	GO:0001966	thigmotaxis
0.45	GO:0007632	visual behavior
0.44	GO:0001654	eye development

0.63	GO:0016779	nucleotidyltransferase activity
0.59	GO:0003723	RNA binding
0.36	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005739	mitochondrion
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0016779

sp|Q96Q15|SMG1_HUMAN
Serine/threonine-protein kinase SMG1
Search

SMG1

0.92	SMG1, nonsense mediated mRNA decay associated PI3K related kinase

0.82	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.66	GO:0032204	regulation of telomere maintenance
0.64	GO:0018105	peptidyl-serine phosphorylation
0.64	GO:0046777	protein autophosphorylation
0.62	GO:2001020	regulation of response to DNA damage stimulus
0.60	GO:0046854	phosphatidylinositol phosphorylation
0.45	GO:0006281	DNA repair

0.70	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0042162	telomeric DNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005654	nucleoplasm
0.42	GO:0005737	cytoplasm

0.70

GO:0004674

sp|Q96Q27|ASB2_HUMAN
Ankyrin repeat and SOCS box protein 2
Search

ASB2

0.97	Ankyrin repeat and SOCS box containing 2

0.69	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.58	GO:0045445	myoblast differentiation
0.57	GO:0035914	skeletal muscle cell differentiation
0.51	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0043687	post-translational protein modification

0.53	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0005515	protein binding

0.59	GO:0031466	Cul5-RING ubiquitin ligase complex
0.34	GO:0005829	cytosol

sp|Q96Q35|AL2SB_HUMAN
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein
Search

ALS2CR12

0.97	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein homolog

0.50

GO:0005515

protein binding

0.80	GO:0001520	outer dense fiber
0.80	GO:0035686	sperm fibrous sheath
0.49	GO:0005737	cytoplasm

sp|Q96Q40|CDK15_HUMAN
Cyclin-dependent kinase 15
Search

CDK15

0.93	Serine/threonine-protein kinase PFTAIRE-2

0.63	GO:0006468	protein phosphorylation
0.51	GO:0051726	regulation of cell cycle
0.50	GO:0000086	G2/M transition of mitotic cell cycle
0.48	GO:0060828	regulation of canonical Wnt signaling pathway
0.39	GO:0016055	Wnt signaling pathway
0.38	GO:0051301	cell division
0.33	GO:0007275	multicellular organism development

0.69	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0030332	cyclin binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0042813	Wnt-activated receptor activity
0.34	GO:0046872	metal ion binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding

0.52	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|Q96Q42|ALS2_HUMAN
Alsin
Search

ALS2

0.94	Amyotrophic lateral sclerosis 2 (Juvenile)

0.75	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.61	GO:0051036	regulation of endosome size
0.60	GO:0001881	receptor recycling
0.60	GO:0001662	behavioral fear response
0.60	GO:0035249	synaptic transmission, glutamatergic
0.58	GO:0007528	neuromuscular junction development
0.57	GO:0007032	endosome organization
0.56	GO:0007626	locomotory behavior
0.55	GO:0048812	neuron projection morphogenesis

0.75	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.59	GO:0048365	Rac GTPase binding
0.58	GO:0043539	protein serine/threonine kinase activator activity
0.58	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.53	GO:0042803	protein homodimerization activity
0.35	GO:0005096	GTPase activator activity

0.58	GO:0043197	dendritic spine
0.57	GO:0014069	postsynaptic density
0.57	GO:0001726	ruffle
0.57	GO:0030027	lamellipodium
0.56	GO:0005769	early endosome
0.55	GO:0005813	centrosome
0.50	GO:0005829	cytosol
0.45	GO:0043234	protein complex
0.39	GO:0030426	growth cone
0.39	GO:0043025	neuronal cell body

sp|Q96Q45|TM237_HUMAN
Transmembrane protein 237
Search

TMEM237

0.97	Transmembrane protein 237

0.54	GO:0030111	regulation of Wnt signaling pathway
0.53	GO:0060271	cilium assembly

0.34

GO:0005515

protein binding

0.55	GO:0035869	ciliary transition zone
0.30	GO:0016021	integral component of membrane

sp|Q96Q77|CIB3_HUMAN
Calcium and integrin-binding family member 3
Search

CIB3

0.97	Kinase-interacting protein 3

0.64	GO:0007229	integrin-mediated signaling pathway
0.42	GO:0055074	calcium ion homeostasis
0.40	GO:0009605	response to external stimulus
0.40	GO:0009628	response to abiotic stimulus
0.40	GO:0048884	neuromast development
0.39	GO:0045494	photoreceptor cell maintenance
0.39	GO:0046683	response to organophosphorus
0.39	GO:0014074	response to purine-containing compound
0.38	GO:0043010	camera-type eye development
0.38	GO:0035690	cellular response to drug

0.70	GO:0005509	calcium ion binding
0.46	GO:0000287	magnesium ion binding
0.39	GO:0005178	integrin binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0016301	kinase activity
0.34	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0032437	cuticular plate
0.40	GO:0005927	muscle tendon junction
0.39	GO:0001917	photoreceptor inner segment
0.39	GO:0032420	stereocilium
0.39	GO:0031594	neuromuscular junction
0.39	GO:0001750	photoreceptor outer segment
0.39	GO:0042383	sarcolemma
0.34	GO:0005955	calcineurin complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0016773

sp|Q96Q80|DERL3_HUMAN
Derlin-3
Search

DERL3

0.68

Derlin

0.62	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.58	GO:0030968	endoplasmic reticulum unfolded protein response
0.57	GO:0030433	ubiquitin-dependent ERAD pathway
0.52	GO:0018279	protein N-linked glycosylation via asparagine
0.51	GO:0001967	suckling behavior
0.50	GO:0030970	retrograde protein transport, ER to cytosol
0.49	GO:0030307	positive regulation of cell growth
0.47	GO:0008284	positive regulation of cell proliferation
0.35	GO:1904380	endoplasmic reticulum mannose trimming

0.34

GO:0005515

protein binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.57	GO:0005791	rough endoplasmic reticulum
0.55	GO:0048500	signal recognition particle
0.51	GO:0098588	bounding membrane of organelle
0.48	GO:0005770	late endosome
0.47	GO:0005769	early endosome
0.47	GO:0098796	membrane protein complex
0.35	GO:0044322	endoplasmic reticulum quality control compartment
0.30	GO:0016021	integral component of membrane

sp|Q96Q83|ALKB3_HUMAN
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
Search

ALKBH3

0.97	Alpha-ketoglutarate-dependent dioxygenase alkB like protein 3

0.84	GO:0035552	oxidative single-stranded DNA demethylation
0.79	GO:0006307	DNA dealkylation involved in DNA repair
0.56	GO:0035553	oxidative single-stranded RNA demethylation
0.52	GO:0008283	cell proliferation
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.70	GO:0051213	dioxygenase activity
0.59	GO:1990930	RNA N1-methyladenosine dioxygenase activity
0.51	GO:0008198	ferrous iron binding
0.50	GO:0051747	cytosine C-5 DNA demethylase activity
0.47	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0004527	exonuclease activity
0.35	GO:0031418	L-ascorbic acid binding
0.35	GO:0004519	endonuclease activity
0.33	GO:0005515	protein binding
0.33	GO:0030170	pyridoxal phosphate binding

0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:1.14

GO:0016705

sp|Q96Q89|KI20B_HUMAN
Kinesin-like protein KIF20B
Search

KIF20B

0.94	Kinesin family member 20Bb

0.77	GO:2001224	positive regulation of neuron migration
0.77	GO:0035372	protein localization to microtubule
0.75	GO:0007088	regulation of mitotic nuclear division
0.75	GO:1903438	positive regulation of mitotic cytokinetic process
0.74	GO:0007018	microtubule-based movement
0.73	GO:0001843	neural tube closure
0.72	GO:0090316	positive regulation of intracellular protein transport
0.68	GO:0048812	neuron projection morphogenesis
0.68	GO:0008284	positive regulation of cell proliferation
0.67	GO:2000114	regulation of establishment of cell polarity

0.76	GO:0050699	WW domain binding
0.75	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.65	GO:0042803	protein homodimerization activity
0.56	GO:0042623	ATPase activity, coupled
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0097431	mitotic spindle pole
0.74	GO:1990023	mitotic spindle midzone
0.73	GO:0070938	contractile ring
0.72	GO:0030496	midbody
0.68	GO:0048471	perinuclear region of cytoplasm
0.68	GO:0005813	centrosome
0.64	GO:0005730	nucleolus
0.61	GO:0005654	nucleoplasm
0.56	GO:0005871	kinesin complex

sp|Q96Q91|B3A4_HUMAN
Anion exchange protein 4
Search

0.64	Electrogenic sodium bicarbonate cotransporter 1

0.69	GO:0098656	anion transmembrane transport
0.69	GO:0015698	inorganic anion transport
0.57	GO:0015701	bicarbonate transport
0.52	GO:0035725	sodium ion transmembrane transport
0.50	GO:0051453	regulation of intracellular pH
0.37	GO:0045947	negative regulation of translational initiation

0.83	GO:0005452	inorganic anion exchanger activity
0.59	GO:0008510	sodium:bicarbonate symporter activity
0.39	GO:0015301	anion:anion antiporter activity
0.38	GO:0008190	eukaryotic initiation factor 4E binding
0.35	GO:0003723	RNA binding
0.35	GO:0042802	identical protein binding

0.54	GO:0045177	apical part of cell
0.47	GO:0016323	basolateral plasma membrane
0.44	GO:0005887	integral component of plasma membrane
0.35	GO:0070062	extracellular exosome

sp|Q96QA5|GSDMA_HUMAN
Gasdermin-A
Search

GSDMA

0.97	Gasdermin-A

0.77	GO:0012501	programmed cell death
0.43	GO:0036331	avascular cornea development in camera-type eye
0.42	GO:0001949	sebaceous gland cell differentiation
0.42	GO:0051886	negative regulation of timing of anagen
0.41	GO:0031069	hair follicle morphogenesis
0.40	GO:0035019	somatic stem cell population maintenance
0.40	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.40	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.39	GO:0042176	regulation of protein catabolic process
0.37	GO:0050790	regulation of catalytic activity

0.37

GO:0030234

enzyme regulator activity

0.78	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.38	GO:1905369	endopeptidase complex
0.36	GO:0005634	nucleus
0.35	GO:0043234	protein complex

sp|Q96QA6|YPEL2_HUMAN
Protein yippee-like 2
Search

sp|Q96QB1|RHG07_HUMAN
Rho GTPase-activating protein 7
Search

DLC1

0.91	Rho GTPase-activating protein 7

0.77	GO:0035023	regulation of Rho protein signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.56	GO:1900119	positive regulation of execution phase of apoptosis
0.56	GO:0051497	negative regulation of stress fiber assembly
0.56	GO:0051895	negative regulation of focal adhesion assembly
0.54	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.54	GO:0035307	positive regulation of protein dephosphorylation
0.54	GO:0046580	negative regulation of Ras protein signal transduction
0.53	GO:0030336	negative regulation of cell migration

0.75	GO:0005096	GTPase activator activity
0.71	GO:0008289	lipid binding
0.55	GO:0042169	SH2 domain binding
0.35	GO:0043274	phospholipase binding
0.35	GO:0017166	vinculin binding

0.54	GO:0032587	ruffle membrane
0.54	GO:0005901	caveola
0.53	GO:0005925	focal adhesion
0.52	GO:0030864	cortical actin cytoskeleton
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.35	GO:0097517	contractile actin filament bundle
0.35	GO:0042641	actomyosin
0.35	GO:0005884	actin filament

sp|Q96QC0|PP1RA_HUMAN
Serine/threonine-protein phosphatase 1 regulatory subunit 10
Search

PPP1R10

0.93	Phosphatase 1 nuclear targeting subunit

0.46	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.38	GO:0006606	protein import into nucleus

0.52	GO:0046872	metal ion binding
0.46	GO:0004864	protein phosphatase inhibitor activity
0.39	GO:0003723	RNA binding
0.38	GO:0003677	DNA binding
0.36	GO:0005515	protein binding

0.69	GO:0072357	PTW/PP1 phosphatase complex
0.66	GO:0000784	nuclear chromosome, telomeric region
0.64	GO:0016604	nuclear body
0.60	GO:0000785	chromatin

sp|Q96QD5|DEPD7_HUMAN
DEP domain-containing protein 7
Search

DEPDC7

0.94	DEP domain-containing protein 7

0.62	GO:0035556	intracellular signal transduction
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0043547	positive regulation of GTPase activity

0.35

GO:0005096

GTPase activator activity

0.45

GO:0005622

intracellular

sp|Q96QD8|S38A2_HUMAN
Sodium-coupled neutral amino acid transporter 2
Search

SLC38A2

0.95	Sodium-dependent neutral amino acid transporter-2

0.52	GO:0006868	glutamine transport
0.48	GO:0003333	amino acid transmembrane transport
0.44	GO:0006814	sodium ion transport
0.42	GO:0071260	cellular response to mechanical stimulus
0.42	GO:0034198	cellular response to amino acid starvation
0.42	GO:0007565	female pregnancy
0.42	GO:0021987	cerebral cortex development
0.41	GO:0031460	glycine betaine transport
0.40	GO:0032328	alanine transport
0.38	GO:0014047	glutamate secretion

0.53	GO:0015186	L-glutamine transmembrane transporter activity
0.44	GO:0015293	symporter activity
0.34	GO:0005515	protein binding

0.42	GO:0042383	sarcolemma
0.42	GO:0005903	brush border
0.41	GO:0005887	integral component of plasma membrane
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon

sp|Q96QD9|UIF_HUMAN
UAP56-interacting factor
Search

FYTTD1

0.97	Forty-two-three domain-containing protein 1

0.81	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0051028	mRNA transport
0.75	GO:0006405	RNA export from nucleus
0.54	GO:0010467	gene expression

0.76	GO:0003729	mRNA binding
0.34	GO:0005515	protein binding

0.58	GO:0016607	nuclear speck
0.30	GO:0044425	membrane part

sp|Q96QE2|MYCT_HUMAN
Proton myo-inositol cotransporter
Search

SLC2A13

0.96	Solute carrier family 2 (Facilitated glucose transporter), member 13

0.57	GO:0008643	carbohydrate transport
0.55	GO:0055085	transmembrane transport
0.43	GO:0015992	proton transport

0.57

GO:0022857

transmembrane transporter activity

0.30

GO:0016020

membrane

sp|Q96QE3|ATAD5_HUMAN
ATPase family AAA domain-containing protein 5
Search

ATAD5

0.86	LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 5

0.67	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.65	GO:0030890	positive regulation of B cell proliferation
0.64	GO:0002377	immunoglobulin production
0.59	GO:1901990	regulation of mitotic cell cycle phase transition
0.37	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:0033260	nuclear DNA replication

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

EC:2.4

GO:0016757

sp|Q96QE4|LR37B_HUMAN
Leucine-rich repeat-containing protein 37B
Search

LRRC37B

0.97	Leucine-rich repeat-containing protein 37B

0.30

GO:0044425

membrane part

sp|Q96QE5|TEFM_HUMAN
Transcription elongation factor, mitochondrial
Search

TEFM

0.97	Transcription elongation factor, mitochondrial

0.77	GO:0006390	mitochondrial transcription
0.57	GO:0006119	oxidative phosphorylation
0.54	GO:0006259	DNA metabolic process
0.52	GO:0006414	translational elongation
0.43	GO:0000002	mitochondrial genome maintenance
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression

0.74	GO:0030337	DNA polymerase processivity factor activity
0.52	GO:0003746	translation elongation factor activity
0.42	GO:0008821	crossover junction endodeoxyribonuclease activity
0.36	GO:0005515	protein binding

0.73	GO:0042645	mitochondrial nucleoid
0.55	GO:0030529	intracellular ribonucleoprotein complex

0.42

EC:3.1.22.4

GO:0008821

sp|Q96QF0|RAB3I_HUMAN
Rab-3A-interacting protein
Search

RAB3IP

0.87	Rab-3A-interacting protein isoform alpha 1

0.70	GO:0006612	protein targeting to membrane
0.62	GO:0065009	regulation of molecular function
0.54	GO:0070121	Kupffer's vesicle development
0.54	GO:0032402	melanosome transport
0.45	GO:0060271	cilium assembly
0.43	GO:0033365	protein localization to organelle
0.42	GO:0051490	negative regulation of filopodium assembly
0.41	GO:0006893	Golgi to plasma membrane transport
0.40	GO:0140056	organelle localization by membrane tethering

0.79	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.44	GO:0042802	identical protein binding

0.64	GO:0005829	cytosol
0.58	GO:0005634	nucleus
0.46	GO:0030027	lamellipodium
0.45	GO:0005813	centrosome
0.43	GO:0120038	plasma membrane bounded cell projection part
0.40	GO:0097447	dendritic tree
0.39	GO:0005929	cilium
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

sp|Q96QF7|ACRC_HUMAN
Acidic repeat-containing protein
Search

GCNA

0.75	Germ cell nuclear acidic peptidase

0.73	GO:0080111	DNA demethylation
0.43	GO:0006493	protein O-linked glycosylation
0.42	GO:0000469	cleavage involved in rRNA processing
0.41	GO:0042274	ribosomal small subunit biogenesis
0.40	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.37	GO:0045132	meiotic chromosome segregation
0.35	GO:1904808	positive regulation of protein oxidation
0.35	GO:0034514	mitochondrial unfolded protein response
0.35	GO:0036251	positive regulation of transcription from RNA polymerase II promoter in response to salt stress
0.35	GO:0060378	regulation of brood size

0.40	GO:0004521	endoribonuclease activity
0.39	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0003677	DNA binding
0.36	GO:0046872	metal ion binding
0.34	GO:0008146	sulfotransferase activity
0.34	GO:0003723	RNA binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0016987	bacterial sigma factor activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.57	GO:0005634	nucleus
0.36	GO:0000793	condensed chromosome
0.35	GO:0030688	preribosome, small subunit precursor
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

EC:2.4

GO:0016757

sp|Q96QG7|MTMR9_HUMAN
Myotubularin-related protein 9
Search

MTMR9

0.95	Myotubularin related protein 9

0.86	GO:0060304	regulation of phosphatidylinositol dephosphorylation
0.85	GO:0010922	positive regulation of phosphatase activity
0.79	GO:0050821	protein stabilization
0.75	GO:0010507	negative regulation of autophagy
0.39	GO:0006661	phosphatidylinositol biosynthetic process
0.37	GO:0016311	dephosphorylation

0.83	GO:0019903	protein phosphatase binding
0.69	GO:0030234	enzyme regulator activity
0.41	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.41	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.35	GO:0050662	coenzyme binding

0.59	GO:0043234	protein complex
0.49	GO:0005737	cytoplasm

0.41

GO:0052629

sp|Q96QH2|PRAM_HUMAN
PML-RARA-regulated adapter molecule 1
Search

PRAM1

0.92	PML-RARA-regulated adapter molecule 1

0.78	GO:0043313	regulation of neutrophil degranulation
0.68	GO:0007229	integrin-mediated signaling pathway
0.42	GO:0006955	immune response
0.38	GO:0007018	microtubule-based movement
0.35	GO:0044718	siderophore transmembrane transport
0.34	GO:0006897	endocytosis
0.34	GO:0016310	phosphorylation
0.34	GO:0015031	protein transport
0.34	GO:0072554	blood vessel lumenization
0.33	GO:0007155	cell adhesion

0.72	GO:0019901	protein kinase binding
0.44	GO:0008289	lipid binding
0.38	GO:0003777	microtubule motor activity
0.38	GO:0008017	microtubule binding
0.38	GO:0003779	actin binding
0.36	GO:0003676	nucleic acid binding
0.35	GO:0031992	energy transducer activity
0.35	GO:0015343	siderophore transmembrane transporter activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0016301	kinase activity

0.56	GO:0043234	protein complex
0.44	GO:0015629	actin cytoskeleton
0.37	GO:0044430	cytoskeletal part
0.34	GO:0030288	outer membrane-bounded periplasmic space
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96QH8|LYZL5_HUMAN
Sperm acrosome-associated protein 5
Search

0.97	Sperm acrosome-associated protein 5

0.54	GO:0050830	defense response to Gram-positive bacterium
0.53	GO:0050829	defense response to Gram-negative bacterium
0.51	GO:0016998	cell wall macromolecule catabolic process
0.43	GO:0009566	fertilization

0.79	GO:0003796	lysozyme activity
0.37	GO:0046983	protein dimerization activity

0.49

GO:0005615

extracellular space

0.79

EC:3.2.1.17

GO:0003796

sp|Q96QI5|HS3S6_HUMAN
Heparan sulfate glucosamine 3-O-sulfotransferase 6
Search

0.56	Sulfotransferase

0.34	GO:0006477	protein sulfation
0.34	GO:0003341	cilium movement
0.34	GO:0060271	cilium assembly
0.33	GO:0030260	entry into host cell
0.33	GO:0019058	viral life cycle

0.76

GO:0008146

sulfotransferase activity

0.33

GO:0005887

integral component of plasma membrane

0.76

GO:0008146

sp|Q96QK1|VPS35_HUMAN
Vacuolar protein sorting-associated protein 35
Search

VPS35

0.72	Vacuolar protein sorting-associated protein 35

0.79	GO:0042147	retrograde transport, endosome to Golgi
0.64	GO:0015031	protein transport
0.60	GO:1903336	negative regulation of vacuolar transport
0.60	GO:1902822	regulation of late endosome to lysosome transport
0.59	GO:0099074	mitochondrion to lysosome transport
0.58	GO:0060161	positive regulation of dopamine receptor signaling pathway
0.58	GO:1902950	regulation of dendritic spine maintenance
0.58	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.57	GO:2000331	regulation of terminal button organization
0.57	GO:0045056	transcytosis

0.59	GO:0031748	D1 dopamine receptor binding
0.43	GO:0008565	protein transporter activity
0.34	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008144	drug binding

0.82	GO:0030906	retromer, cargo-selective complex
0.67	GO:0005829	cytosol
0.59	GO:0099073	mitochondrion-derived vesicle
0.58	GO:0097422	tubular endosome
0.53	GO:0005769	early endosome
0.52	GO:0005764	lysosome
0.52	GO:0010008	endosome membrane
0.50	GO:0014069	postsynaptic density
0.49	GO:0043025	neuronal cell body
0.48	GO:0048471	perinuclear region of cytoplasm

sp|Q96QK8|SIM14_HUMAN
Small integral membrane protein 14
Search

SMIM14

0.97	Small integral membrane protein 14

0.33	GO:0055114	oxidation-reduction process
0.32	GO:0006024	glycosaminoglycan biosynthetic process

0.34	GO:0051287	NAD binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.33	GO:0005515	protein binding

0.50	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.32	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016616

sp|Q96QP1|ALPK1_HUMAN
Alpha-protein kinase 1
Search

ALPK1

0.91	Alpha-protein kinase 1

0.62	GO:0006468	protein phosphorylation
0.35	GO:0006414	translational elongation

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003746	translation elongation factor activity

0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

sp|Q96QR1|SG3A1_HUMAN
Secretoglobin family 3A member 1
Search

SCGB3A1

0.96	Secretoglobin family 3A member 1

0.79	GO:1901741	positive regulation of myoblast fusion
0.52	GO:0030308	negative regulation of cell growth
0.49	GO:0042127	regulation of cell proliferation
0.49	GO:0010469	regulation of receptor activity

0.51

GO:0005125

cytokine activity

0.73	GO:0005615	extracellular space
0.51	GO:1903561	extracellular vesicle

sp|Q96QR8|PURB_HUMAN
Transcriptional activator protein Pur-beta
Search

PURB

0.94	Transcriptional activator protein Pur-beta-A

0.75	GO:0008283	cell proliferation
0.72	GO:0030154	cell differentiation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.49	GO:0042127	regulation of cell proliferation
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0006268	DNA unwinding involved in DNA replication
0.40	GO:0017148	negative regulation of translation
0.39	GO:0007399	nervous system development
0.38	GO:0048522	positive regulation of cellular process
0.37	GO:0006351	transcription, DNA-templated

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.52	GO:0046332	SMAD binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.48	GO:0008134	transcription factor binding
0.46	GO:0003729	mRNA binding
0.43	GO:0000900	translation repressor activity, nucleic acid binding
0.34	GO:0015002	heme-copper terminal oxidase activity
0.34	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.54	GO:0005662	DNA replication factor A complex
0.40	GO:0043025	neuronal cell body
0.40	GO:0030425	dendrite
0.34	GO:0005737	cytoplasm
0.33	GO:0031967	organelle envelope
0.33	GO:0000786	nucleosome
0.33	GO:0000784	nuclear chromosome, telomeric region
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.9

GO:0016675

sp|Q96QS1|TSN32_HUMAN
Tetraspanin-32
Search

TSPAN32

0.96	Pan-hematopoietic expression protein

0.68	GO:0030886	negative regulation of myeloid dendritic cell activation
0.65	GO:0042832	defense response to protozoan
0.65	GO:0070527	platelet aggregation
0.63	GO:0050688	regulation of defense response to virus
0.60	GO:0007229	integrin-mediated signaling pathway
0.59	GO:0008285	negative regulation of cell proliferation
0.54	GO:0007010	cytoskeleton organization
0.38	GO:0007267	cell-cell signaling

0.69	GO:0070442	integrin alphaIIb-beta3 complex
0.57	GO:0009986	cell surface
0.39	GO:0005622	intracellular

sp|Q96QS3|ARX_HUMAN
Homeobox protein ARX
Search

ARX

0.85	Homeobox protein ARX

0.65	GO:0007275	multicellular organism development
0.56	GO:0044241	lipid digestion
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0072148	epithelial cell fate commitment
0.55	GO:0010468	regulation of gene expression
0.55	GO:0048857	neural nucleus development
0.54	GO:0060322	head development
0.54	GO:0046622	positive regulation of organ growth
0.53	GO:0061351	neural precursor cell proliferation

0.63	GO:0043565	sequence-specific DNA binding
0.56	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0035326	enhancer binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003682	chromatin binding
0.48	GO:0003690	double-stranded DNA binding
0.34	GO:0004864	protein phosphatase inhibitor activity
0.33	GO:0003779	actin binding

0.61

GO:0005634

nucleus

sp|Q96QS6|KPSH2_HUMAN
Serine/threonine-protein kinase H2
Search

PSKH1

0.64	Serine/threonine-protein kinase H2

0.63	GO:0006468	protein phosphorylation
0.54	GO:0007368	determination of left/right symmetry
0.52	GO:0007507	heart development
0.51	GO:0018210	peptidyl-threonine modification
0.50	GO:0018209	peptidyl-serine modification
0.43	GO:0035556	intracellular signal transduction
0.34	GO:0018212	peptidyl-tyrosine modification

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004713	protein tyrosine kinase activity
0.33	GO:0005515	protein binding

0.48	GO:0005654	nucleoplasm
0.36	GO:0005815	microtubule organizing center
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005794	Golgi apparatus
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0004674

sp|Q96QT4|TRPM7_HUMAN
Transient receptor potential cation channel subfamily M member 7
Search

TRPM7

0.96	Transient receptor potential cation channel subfamily M member 7

0.86	GO:0010961	cellular magnesium ion homeostasis
0.78	GO:0051262	protein tetramerization
0.66	GO:0016340	calcium-dependent cell-matrix adhesion
0.63	GO:0070266	necroptotic process
0.63	GO:0006468	protein phosphorylation
0.60	GO:0006812	cation transport
0.59	GO:0031032	actomyosin structure organization
0.59	GO:0034220	ion transmembrane transport
0.37	GO:0016579	protein deubiquitination
0.36	GO:0006511	ubiquitin-dependent protein catabolic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.68	GO:0005216	ion channel activity
0.60	GO:0017022	myosin binding
0.56	GO:0015085	calcium ion transmembrane transporter activity
0.54	GO:0003779	actin binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0046872	metal ion binding

0.59	GO:0001726	ruffle
0.44	GO:0005886	plasma membrane
0.37	GO:0043196	varicosity
0.36	GO:0030672	synaptic vesicle membrane
0.36	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|Q96QT6|PHF12_HUMAN
PHD finger protein 12
Search

PHF12

0.94	Putative phd finger protein 12 isoform 2 phd zinc finger transcription factor

0.59	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.66	GO:0001222	transcription corepressor binding
0.64	GO:0001106	RNA polymerase II transcription corepressor activity
0.58	GO:0035091	phosphatidylinositol binding
0.53	GO:0046872	metal ion binding
0.48	GO:0042393	histone binding
0.48	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.47	GO:0003682	chromatin binding

0.64	GO:0016580	Sin3 complex
0.61	GO:0017053	transcriptional repressor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q96QU1|PCD15_HUMAN
Protocadherin-15
Search

PCDH15

0.93	Protocadherin-15

0.82	GO:0048839	inner ear development
0.82	GO:0007605	sensory perception of sound
0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.51	GO:0050973	detection of mechanical stimulus involved in equilibrioception
0.49	GO:0060013	righting reflex
0.48	GO:0001964	startle response
0.48	GO:0007628	adult walking behavior
0.48	GO:0035315	hair cell differentiation
0.47	GO:0060563	neuroepithelial cell differentiation
0.47	GO:0042490	mechanoreceptor differentiation

0.70	GO:0005509	calcium ion binding
0.35	GO:0047485	protein N-terminus binding
0.34	GO:0032403	protein complex binding

0.85	GO:0032420	stereocilium
0.56	GO:0005886	plasma membrane
0.48	GO:0001750	photoreceptor outer segment
0.38	GO:0045202	synapse
0.37	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q96QU4|FRG2B_HUMAN
Protein FRG2-like-1
Search

sp|Q96QU6|1A1L1_HUMAN
1-aminocyclopropane-1-carboxylate synthase-like protein 1
Search

ACCS

0.95	1-aminocyclopropane-1-carboxylate synthase homolog

0.49	GO:0009058	biosynthetic process
0.34	GO:0043413	macromolecule glycosylation
0.34	GO:0009100	glycoprotein metabolic process
0.33	GO:0072662	protein localization to peroxisome
0.33	GO:0043574	peroxisomal transport
0.33	GO:0036211	protein modification process
0.33	GO:0072594	establishment of protein localization to organelle
0.32	GO:0006605	protein targeting
0.32	GO:0044267	cellular protein metabolic process

0.67	GO:0030170	pyridoxal phosphate binding
0.50	GO:0042802	identical protein binding
0.41	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0042623	ATPase activity, coupled
0.32	GO:0005524	ATP binding

0.33	GO:0031903	microbody membrane
0.33	GO:0044439	peroxisomal part
0.30	GO:0016021	integral component of membrane

0.41	EC:4.4.1.14	GO:0016847
0.41	KEGG:R00179	GO:0016847

sp|Q96QU8|XPO6_HUMAN
Exportin-6
Search

XPO6

0.93	Exportin-6-B

0.66	GO:0006886	intracellular protein transport
0.58	GO:0006611	protein export from nucleus

0.76	GO:0008536	Ran GTPase binding
0.51	GO:0008565	protein transporter activity

0.60	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005886	plasma membrane

sp|Q96QV1|HHIP_HUMAN
Hedgehog-interacting protein
Search

HHIP

0.96	Hedgehog-interacting protein isoform B

0.64	GO:0045879	negative regulation of smoothened signaling pathway
0.59	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.59	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.58	GO:0007405	neuroblast proliferation
0.57	GO:0007224	smoothened signaling pathway
0.57	GO:0009953	dorsal/ventral pattern formation
0.56	GO:0048705	skeletal system morphogenesis
0.46	GO:0033333	fin development
0.46	GO:0048635	negative regulation of muscle organ development
0.38	GO:0043066	negative regulation of apoptotic process

0.64	GO:0097108	hedgehog family protein binding
0.47	GO:0008270	zinc ion binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.32	GO:0005044	scavenger receptor activity
0.32	GO:0020037	heme binding
0.31	GO:0009055	electron transfer activity
0.31	GO:0005509	calcium ion binding

0.53	GO:0009986	cell surface
0.51	GO:0031226	intrinsic component of plasma membrane
0.36	GO:0060170	ciliary membrane
0.35	GO:0005634	nucleus
0.35	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q96QV6|H2A1A_HUMAN
Histone H2A type 1-A
Search

0.10	Histone H2A type 1-A

0.48	GO:0006342	chromatin silencing
0.46	GO:0050830	defense response to Gram-positive bacterium
0.44	GO:0045087	innate immune response
0.44	GO:0000077	DNA damage checkpoint
0.43	GO:0007283	spermatogenesis
0.43	GO:0051673	membrane disruption in other organism
0.43	GO:0000724	double-strand break repair via homologous recombination
0.35	GO:0071478	cellular response to radiation
0.34	GO:0090398	cellular senescence
0.34	GO:0010332	response to gamma radiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.43	GO:0042393	histone binding
0.41	GO:0019899	enzyme binding
0.32	GO:0008270	zinc ion binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.46	GO:0001741	XY body
0.44	GO:0035861	site of double-strand break
0.44	GO:0000781	chromosome, telomeric region
0.43	GO:0005615	extracellular space
0.43	GO:0005813	centrosome
0.43	GO:0000793	condensed chromosome
0.42	GO:0005657	replication fork

sp|Q96QZ0|PANX3_HUMAN
Pannexin-3
Search

PANX

0.92

Pannexin

0.58	GO:0006811	ion transport
0.51	GO:0034214	protein hexamerization
0.50	GO:0050717	positive regulation of interleukin-1 alpha secretion
0.49	GO:0007267	cell-cell signaling
0.49	GO:0050718	positive regulation of interleukin-1 beta secretion
0.48	GO:0002931	response to ischemia
0.47	GO:0033198	response to ATP
0.43	GO:1904888	cranial skeletal system development
0.43	GO:0001503	ossification
0.42	GO:0055085	transmembrane transport

0.53	GO:0055077	gap junction hemi-channel activity
0.49	GO:0022842	narrow pore channel activity
0.46	GO:0005262	calcium channel activity
0.45	GO:0051015	actin filament binding
0.43	GO:0005102	receptor binding
0.37	GO:0097110	scaffold protein binding
0.37	GO:0044325	ion channel binding
0.37	GO:0002020	protease binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0009982	pseudouridine synthase activity

0.80	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.50	GO:0032059	bleb
0.48	GO:0012505	endomembrane system
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0044444	cytoplasmic part
0.37	GO:0043229	intracellular organelle
0.34	GO:0043234	protein complex
0.34	GO:0044422	organelle part
0.33	GO:0001726	ruffle

0.34

GO:0009982

sp|Q96QZ7|MAGI1_HUMAN
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
Search

MAGI1

0.92	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

0.53	GO:0070997	neuron death
0.49	GO:0016310	phosphorylation
0.35	GO:0007155	cell adhesion
0.35	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0006461	protein complex assembly

0.81	GO:0032947	protein complex scaffold activity
0.54	GO:0051393	alpha-actinin binding
0.51	GO:0016301	kinase activity
0.36	GO:0008022	protein C-terminus binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005923	bicellular tight junction
0.52	GO:0005912	adherens junction
0.47	GO:0005654	nucleoplasm
0.46	GO:0042995	cell projection
0.39	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane

sp|Q96R05|RET7_HUMAN
Retinoid-binding protein 7
Search

RBP7

0.95	Cellular retinol binding protein type III

0.38	GO:0060972	left/right pattern formation
0.38	GO:0061371	determination of heart left/right asymmetry
0.37	GO:0006776	vitamin A metabolic process
0.35	GO:0002138	retinoic acid biosynthetic process
0.34	GO:0008544	epidermis development
0.33	GO:0009435	NAD biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0043632	modification-dependent macromolecule catabolic process
0.33	GO:0030163	protein catabolic process

0.72	GO:0008289	lipid binding
0.38	GO:0043178	alcohol binding
0.35	GO:0019842	vitamin binding
0.34	GO:0016779	nucleotidyltransferase activity
0.33	GO:0034450	ubiquitin-ubiquitin ligase activity
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.34	GO:0005829	cytosol
0.34	GO:0005581	collagen trimer
0.33	GO:0000151	ubiquitin ligase complex
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.34

GO:0016779

sp|Q96R06|SPAG5_HUMAN
Sperm-associated antigen 5
Search

SPAG5

0.97	Sperm-associated antigen 5

0.85	GO:0051988	regulation of attachment of spindle microtubules to kinetochore
0.67	GO:0051301	cell division
0.64	GO:1905832	positive regulation of spindle assembly
0.62	GO:0090235	regulation of metaphase plate congression
0.61	GO:0071539	protein localization to centrosome
0.60	GO:0051294	establishment of spindle orientation
0.58	GO:0032388	positive regulation of intracellular transport
0.57	GO:0007051	spindle organization
0.56	GO:0000070	mitotic sister chromatid segregation

0.54

GO:0008017

microtubule binding

0.61	GO:0034451	centriolar satellite
0.61	GO:0097431	mitotic spindle pole
0.61	GO:0035371	microtubule plus-end
0.58	GO:0005876	spindle microtubule
0.56	GO:0000776	kinetochore
0.44	GO:0030496	midbody
0.44	GO:0000779	condensed chromosome, centromeric region

sp|Q96R08|OR5BC_HUMAN
Olfactory receptor 5B12
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.55	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R09|OR5B2_HUMAN
Olfactory receptor 5B2
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.48	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R27|OR2M4_HUMAN
Olfactory receptor 2M4
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R28|OR2M2_HUMAN
Olfactory receptor 2M2
Search

0.45	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R30|OR2V2_HUMAN
Olfactory receptor 2V2
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R45|OR2A7_HUMAN
Olfactory receptor 2A7
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0032467	positive regulation of cytokinesis
0.34	GO:0032956	regulation of actin cytoskeleton organization

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.37	GO:0090543	Flemming body
0.37	GO:0097431	mitotic spindle pole
0.37	GO:0032154	cleavage furrow
0.37	GO:1990023	mitotic spindle midzone
0.36	GO:0055037	recycling endosome
0.30	GO:0016021	integral component of membrane

sp|Q96R47|O2A14_HUMAN
Olfactory receptor 2A14
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R48|OR2A5_HUMAN
Olfactory receptor 2A5
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R54|O14A2_HUMAN
Olfactory receptor 14A2
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0007411	axon guidance

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R67|OR4CC_HUMAN
Olfactory receptor 4C12
Search

0.45	Seven transmembrane helix receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R69|OR4F4_HUMAN
Olfactory receptor 4F4
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R72|OR4K3_HUMAN
Olfactory receptor 4K3
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96R84|OR1F2_HUMAN
Putative olfactory receptor 1F2
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.36	GO:0005938	cell cortex
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RA2|OR7D2_HUMAN
Olfactory receptor 7D2
Search

0.44	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RB7|OR5MB_HUMAN
Olfactory receptor 5M11
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RC9|OR8B4_HUMAN
Olfactory receptor 8B4
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.53	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RD0|OR8B2_HUMAN
Olfactory receptor 8B2
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.55	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RD1|OR6C1_HUMAN
Olfactory receptor 6C1
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RD2|O52B2_HUMAN
Olfactory receptor 52B2
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RD3|O52E6_HUMAN
Olfactory receptor 52E6
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RD6|PANX2_HUMAN
Pannexin-2
Search

PANX2

0.92

Pannexin

0.57	GO:0002931	response to ischemia
0.55	GO:0006811	ion transport
0.45	GO:0007267	cell-cell signaling
0.42	GO:0055085	transmembrane transport
0.40	GO:0034214	protein hexamerization

0.49	GO:0015267	channel activity
0.34	GO:0046982	protein heterodimerization activity

0.80	GO:0005921	gap junction
0.53	GO:0005886	plasma membrane
0.44	GO:0031410	cytoplasmic vesicle
0.43	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

sp|Q96RD7|PANX1_HUMAN
Pannexin-1
Search

PANX1

0.92

Pannexin

0.62	GO:0050717	positive regulation of interleukin-1 alpha secretion
0.61	GO:0034214	protein hexamerization
0.60	GO:0050718	positive regulation of interleukin-1 beta secretion
0.59	GO:0002931	response to ischemia
0.58	GO:0006811	ion transport
0.58	GO:0033198	response to ATP
0.48	GO:0007267	cell-cell signaling
0.45	GO:0055085	transmembrane transport
0.33	GO:1904888	cranial skeletal system development
0.33	GO:0001503	ossification

0.64	GO:0055077	gap junction hemi-channel activity
0.59	GO:0022842	narrow pore channel activity
0.55	GO:0005262	calcium channel activity
0.54	GO:0051015	actin filament binding
0.51	GO:0005102	receptor binding
0.42	GO:0022832	voltage-gated channel activity
0.41	GO:0097110	scaffold protein binding
0.40	GO:0044325	ion channel binding
0.40	GO:0002020	protease binding
0.38	GO:0046982	protein heterodimerization activity

0.80	GO:0005921	gap junction
0.61	GO:0032059	bleb
0.55	GO:0005886	plasma membrane
0.51	GO:0012505	endomembrane system
0.44	GO:0043227	membrane-bounded organelle
0.43	GO:0044444	cytoplasmic part
0.42	GO:0043229	intracellular organelle
0.39	GO:0001726	ruffle
0.38	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0043234	protein complex

0.33

GO:0009982

sp|Q96RD9|FCRL5_HUMAN
Fc receptor-like protein 5
Search

0.67	LOW QUALITY PROTEIN: Fc receptor-like protein 3

0.55	GO:0009967	positive regulation of signal transduction
0.45	GO:0006898	receptor-mediated endocytosis
0.41	GO:0042113	B cell activation
0.40	GO:0007267	cell-cell signaling
0.36	GO:0007165	signal transduction

0.61	GO:0005070	SH3/SH2 adaptor activity
0.48	GO:0005044	scavenger receptor activity
0.41	GO:0015026	coreceptor activity
0.38	GO:0046982	protein heterodimerization activity
0.35	GO:0003677	DNA binding

0.57	GO:0009986	cell surface
0.38	GO:0000786	nucleosome
0.36	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane
0.30	GO:0043235	receptor complex
0.30	GO:0044425	membrane part

sp|Q96RE7|NACC1_HUMAN
Nucleus accumbens-associated protein 1
Search

NACC1

0.96	Nucleus accumbens-associated protein 1

0.78	GO:0008284	positive regulation of cell proliferation
0.77	GO:0051260	protein homooligomerization
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0006351	transcription, DNA-templated
0.37	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.36	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.36	GO:0034629	cellular protein complex localization
0.36	GO:0016575	histone deacetylation
0.36	GO:0008285	negative regulation of cell proliferation
0.35	GO:0010608	posttranscriptional regulation of gene expression

0.40	GO:0005515	protein binding
0.36	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0004407	histone deacetylase activity
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.77	GO:0016604	nuclear body
0.74	GO:0030054	cell junction
0.37	GO:0005737	cytoplasm
0.36	GO:0016581	NuRD complex
0.35	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.5.1.98

GO:0004407

sp|Q96RE9|ZN300_HUMAN
Zinc finger protein 300
Search

0.63	Zinc finger protein 12

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.47	GO:0043392	negative regulation of DNA binding
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:0006366	transcription by RNA polymerase II

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.47	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.30	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.41	GO:0043227	membrane-bounded organelle
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043228	non-membrane-bounded organelle
0.36	GO:0044422	organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RF0|SNX18_HUMAN
Sorting nexin-18
Search

SNX18

0.70	Sorting nexin

0.66	GO:0000278	mitotic cell cycle
0.58	GO:0015031	protein transport
0.55	GO:0036089	cleavage furrow formation
0.49	GO:0016197	endosomal transport
0.48	GO:0006897	endocytosis
0.48	GO:0043547	positive regulation of GTPase activity
0.38	GO:0070727	cellular macromolecule localization
0.34	GO:0097320	plasma membrane tubulation
0.34	GO:0007032	endosome organization
0.33	GO:0006275	regulation of DNA replication

0.72	GO:0035091	phosphatidylinositol binding
0.35	GO:0005515	protein binding
0.33	GO:0030337	DNA polymerase processivity factor activity
0.32	GO:0003677	DNA binding

0.64	GO:0030659	cytoplasmic vesicle membrane
0.50	GO:0070062	extracellular exosome
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.50	GO:0030136	clathrin-coated vesicle
0.37	GO:0030426	growth cone
0.37	GO:0010008	endosome membrane
0.37	GO:0043025	neuronal cell body
0.33	GO:0005829	cytosol

sp|Q96RG2|PASK_HUMAN
PAS domain-containing serine/threonine-protein kinase
Search

PASK

0.90	PAS domain-containing serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0070092	regulation of glucagon secretion
0.59	GO:0045719	negative regulation of glycogen biosynthetic process
0.59	GO:2000505	regulation of energy homeostasis
0.58	GO:0043576	regulation of respiratory gaseous exchange
0.42	GO:0010468	regulation of gene expression
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.36	GO:0010557	positive regulation of macromolecule biosynthetic process
0.36	GO:0031328	positive regulation of cellular biosynthetic process
0.35	GO:0043066	negative regulation of apoptotic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0035091	phosphatidylinositol binding
0.35	GO:0005515	protein binding
0.33	GO:0004383	guanylate cyclase activity
0.32	GO:0003690	double-stranded DNA binding

0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

EC:4.6.1.2

GO:0004383

sp|Q96RI0|PAR4_HUMAN
Proteinase-activated receptor 4
Search

F2RL3

0.97	F2R like thrombin or trypsin receptor 3

0.81	GO:0070493	thrombin-activated receptor signaling pathway
0.75	GO:0007596	blood coagulation
0.58	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.57	GO:1904064	positive regulation of cation transmembrane transport
0.56	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.56	GO:0051928	positive regulation of calcium ion transport
0.55	GO:0032846	positive regulation of homeostatic process
0.52	GO:0048522	positive regulation of cellular process
0.49	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.46	GO:0048584	positive regulation of response to stimulus

0.81	GO:0015057	thrombin-activated receptor activity
0.45	GO:0004966	galanin receptor activity
0.42	GO:0017046	peptide hormone binding
0.37	GO:0004947	bradykinin receptor activity
0.35	GO:0042923	neuropeptide binding
0.34	GO:0004945	angiotensin type II receptor activity
0.34	GO:0031681	G-protein beta-subunit binding
0.34	GO:0001965	G-protein alpha-subunit binding
0.33	GO:0008233	peptidase activity
0.32	GO:0016500	protein-hormone receptor activity

0.43	GO:0005887	integral component of plasma membrane
0.34	GO:0005576	extracellular region
0.34	GO:0120025	plasma membrane bounded cell projection
0.33	GO:0005769	early endosome

0.33

GO:0008233

sp|Q96RI1|NR1H4_HUMAN
Bile acid receptor
Search

NR1H4

0.97	Farnesoid X-activated receptor

0.78	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.63	GO:2001250	positive regulation of ammonia assimilation cycle
0.62	GO:1905695	positive regulation of phosphatidic acid biosynthetic process
0.62	GO:0072615	interleukin-17 secretion
0.62	GO:0034255	regulation of urea metabolic process
0.62	GO:0038183	bile acid signaling pathway
0.62	GO:0034971	histone H3-R17 methylation
0.62	GO:1904179	positive regulation of adipose tissue development
0.61	GO:1904252	negative regulation of bile acid metabolic process

0.84	GO:0004887	thyroid hormone receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.63	GO:0032052	bile acid binding
0.61	GO:0038181	bile acid receptor activity
0.60	GO:0046965	retinoid X receptor binding
0.57	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.57	GO:0035326	enhancer binding
0.57	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.61	GO:0005634	nucleus
0.57	GO:0000791	euchromatin
0.48	GO:0070013	intracellular organelle lumen

sp|Q96RI8|TAAR6_HUMAN
Trace amine-associated receptor 6
Search

0.96	Trace amine-associated receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007606	sensory perception of chemical stimulus

0.86

GO:0001594

trace-amine receptor activity

0.40	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q96RI9|TAAR9_HUMAN
Trace amine-associated receptor 9
Search

0.96	Trace amine-associated receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007606	sensory perception of chemical stimulus

0.86

GO:0001594

trace-amine receptor activity

0.40	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q96RJ0|TAAR1_HUMAN
Trace amine-associated receptor 1
Search

TAAR1

0.95	Trace amine-associated receptor

0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0006171	cAMP biosynthetic process
0.37	GO:0007606	sensory perception of chemical stimulus
0.35	GO:0019933	cAMP-mediated signaling
0.34	GO:0032098	regulation of appetite
0.34	GO:0007210	serotonin receptor signaling pathway
0.33	GO:0007268	chemical synaptic transmission

0.84	GO:0001594	trace-amine receptor activity
0.34	GO:0099589	serotonin receptor activity
0.34	GO:0099528	G-protein coupled neurotransmitter receptor activity

0.37	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q96RJ3|TR13C_HUMAN
Tumor necrosis factor receptor superfamily member 13C
Search

TNFRSF13C

0.97	LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 13C

0.73	GO:0031296	B cell costimulation
0.72	GO:0002636	positive regulation of germinal center formation
0.71	GO:0045078	positive regulation of interferon-gamma biosynthetic process
0.69	GO:0031295	T cell costimulation
0.69	GO:0001782	B cell homeostasis
0.68	GO:0030890	positive regulation of B cell proliferation
0.67	GO:0042102	positive regulation of T cell proliferation
0.45	GO:0002250	adaptive immune response
0.43	GO:0033209	tumor necrosis factor-mediated signaling pathway

0.64	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q96RJ6|FER3L_HUMAN
Fer3-like protein
Search

FERD3L

0.97	Fer3 like bHLH transcription factor

0.62	GO:0033504	floor plate development
0.55	GO:0050767	regulation of neurogenesis
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0048468	cell development
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.57	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.35	GO:0000829	inositol heptakisphosphate kinase activity

0.46

GO:0005634

nucleus

sp|Q96RK0|CIC_HUMAN
Protein capicua homolog
Search

CIC

0.97	Capicua transcriptional repressor

0.56	GO:0048286	lung alveolus development
0.56	GO:0035176	social behavior
0.55	GO:0007613	memory
0.55	GO:0007612	learning
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0007420	brain development
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0060319	primitive erythrocyte differentiation
0.32	GO:0005975	carbohydrate metabolic process

0.55	GO:0003677	DNA binding
0.52	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex
0.41	GO:0044446	intracellular organelle part
0.33	GO:0000428	DNA-directed RNA polymerase complex

sp|Q96RK1|CITE4_HUMAN
Cbp/p300-interacting transactivator 4
Search

CITED4

0.97	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4

0.58	GO:0043627	response to estrogen
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:0006366	transcription by RNA polymerase II
0.44	GO:0032502	developmental process
0.37	GO:0036211	protein modification process
0.37	GO:0030433	ubiquitin-dependent ERAD pathway
0.36	GO:0035556	intracellular signal transduction

0.56	GO:0003713	transcription coactivator activity
0.48	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.46	GO:0001104	RNA polymerase II transcription cofactor activity
0.38	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0000287	magnesium ion binding
0.36	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0005524	ATP binding
0.35	GO:0005515	protein binding
0.34	GO:0098772	molecular function regulator
0.33	GO:0016874	ligase activity

0.60	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.36	GO:0000151	ubiquitin ligase complex
0.36	GO:0044446	intracellular organelle part
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0043233	organelle lumen
0.32	GO:0099512	supramolecular fiber
0.32	GO:0015630	microtubule cytoskeleton
0.32	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0004674

sp|Q96RK4|BBS4_HUMAN
Bardet-Biedl syndrome 4 protein
Search

BBS4

0.96	Bardet-Biedl syndrome 4 protein homolog

0.85	GO:0035845	photoreceptor cell outer segment organization
0.82	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway
0.81	GO:0060613	fat pad development
0.81	GO:0060295	regulation of cilium movement involved in cell motility
0.81	GO:1903546	protein localization to photoreceptor outer segment
0.80	GO:1902855	regulation of non-motile cilium assembly
0.80	GO:0046548	retinal rod cell development
0.80	GO:0003356	regulation of cilium beat frequency
0.80	GO:0003085	negative regulation of systemic arterial blood pressure
0.79	GO:0021756	striatum development

0.81	GO:0034452	dynactin binding
0.78	GO:0001103	RNA polymerase II repressing transcription factor binding
0.77	GO:0043014	alpha-tubulin binding
0.75	GO:0048487	beta-tubulin binding
0.67	GO:0003777	microtubule motor activity

0.81	GO:0034451	centriolar satellite
0.79	GO:0000242	pericentriolar material
0.77	GO:0060170	ciliary membrane
0.77	GO:0001917	photoreceptor inner segment
0.77	GO:0035869	ciliary transition zone
0.77	GO:0034464	BBSome
0.76	GO:0097730	non-motile cilium
0.74	GO:0036064	ciliary basal body
0.73	GO:0005814	centriole
0.73	GO:0031514	motile cilium

sp|Q96RL1|UIMC1_HUMAN
BRCA1-A complex subunit RAP80
Search

UIMC1

0.96	Ubiquitin interaction motif containing 1

0.86	GO:0070537	histone H2A K63-linked deubiquitination
0.84	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.83	GO:0045739	positive regulation of DNA repair
0.78	GO:0010212	response to ionizing radiation
0.73	GO:0006302	double-strand break repair
0.68	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0000726	non-recombinational repair
0.39	GO:0006351	transcription, DNA-templated
0.35	GO:0001678	cellular glucose homeostasis
0.34	GO:0046835	carbohydrate phosphorylation

0.84	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.77	GO:0042393	histone binding
0.44	GO:0046965	retinoid X receptor binding
0.35	GO:0005536	glucose binding
0.35	GO:0004396	hexokinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0070531	BRCA1-A complex
0.74	GO:0016604	nuclear body
0.30	GO:0016020	membrane

0.35

EC:2.7.1.1

GO:0004396

sp|Q96RL6|SIG11_HUMAN
Sialic acid-binding Ig-like lectin 11
Search

0.94	Sialic acid binding Ig like lectin 11

0.54	GO:0106015	negative regulation of inflammatory response to wounding
0.44	GO:0002244	hematopoietic progenitor cell differentiation
0.41	GO:0007155	cell adhesion
0.39	GO:0045087	innate immune response
0.38	GO:0002250	adaptive immune response
0.34	GO:0043312	neutrophil degranulation

0.51	GO:0030246	carbohydrate binding
0.48	GO:0042169	SH2 domain binding
0.47	GO:0019902	phosphatase binding

0.39	GO:0005886	plasma membrane
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q96RL7|VP13A_HUMAN
Vacuolar protein sorting-associated protein 13A
Search

VPS13A

0.79	Vacuolar protein sorting-associated protein 13A

0.84	GO:0035176	social behavior
0.79	GO:0007626	locomotory behavior
0.77	GO:0006914	autophagy
0.72	GO:0007399	nervous system development
0.44	GO:0006895	Golgi to endosome transport
0.43	GO:0015031	protein transport

0.38

GO:0005515

protein binding

0.85	GO:0031045	dense core granule
0.40	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q96RM1|SPR2F_HUMAN
Small proline-rich protein 2F
Search

0.97	Small proline-rich protein 2F

0.63	GO:0018149	peptide cross-linking
0.58	GO:0030216	keratinocyte differentiation
0.44	GO:0032355	response to estradiol
0.40	GO:0012501	programmed cell death
0.36	GO:0008585	female gonad development
0.34	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.34	GO:0071277	cellular response to calcium ion
0.34	GO:0050890	cognition
0.33	GO:0007010	cytoskeleton organization

0.46	GO:0005198	structural molecule activity
0.39	GO:0030674	protein binding, bridging
0.33	GO:0046983	protein dimerization activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016301	kinase activity

0.78	GO:0001533	cornified envelope
0.42	GO:0005737	cytoplasm
0.38	GO:0005634	nucleus
0.34	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

sp|Q96RN1|S26A8_HUMAN
Testis anion transporter 1
Search

SLC26A8

0.97	Testis anion transporter 1

0.85	GO:0048240	sperm capacitation
0.84	GO:0030317	flagellated sperm motility
0.75	GO:1902358	sulfate transmembrane transport
0.74	GO:0051321	meiotic cell cycle
0.69	GO:0019532	oxalate transport
0.67	GO:0007275	multicellular organism development
0.62	GO:1902476	chloride transmembrane transport
0.55	GO:0015701	bicarbonate transport
0.54	GO:0051453	regulation of intracellular pH
0.51	GO:0042391	regulation of membrane potential

0.78	GO:0008271	secondary active sulfate transmembrane transporter activity
0.69	GO:0019531	oxalate transmembrane transporter activity
0.63	GO:0015108	chloride transmembrane transporter activity
0.62	GO:0005253	anion channel activity
0.56	GO:0015106	bicarbonate transmembrane transporter activity
0.55	GO:0015301	anion:anion antiporter activity
0.35	GO:0005515	protein binding
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005509	calcium ion binding

0.48	GO:0005886	plasma membrane
0.35	GO:0097225	sperm midpiece
0.33	GO:0005903	brush border
0.33	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

sp|Q96RN5|MED15_HUMAN
Mediator of RNA polymerase II transcription subunit 15
Search

MED15

0.96	Mediator of RNA polymerase II transcription subunit 15

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.38	GO:0019827	stem cell population maintenance

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RP3|UCN2_HUMAN
Urocortin-2
Search

0.84	GO:0007586	digestion
0.76	GO:0010469	regulation of receptor activity
0.69	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.62	GO:0009755	hormone-mediated signaling pathway
0.62	GO:0006950	response to stress
0.55	GO:0031669	cellular response to nutrient levels
0.44	GO:0010951	negative regulation of endopeptidase activity
0.42	GO:0033685	negative regulation of luteinizing hormone secretion
0.42	GO:0046882	negative regulation of follicle-stimulating hormone secretion
0.40	GO:0071385	cellular response to glucocorticoid stimulus

0.87	GO:0051431	corticotropin-releasing hormone receptor 2 binding
0.79	GO:0005179	hormone activity
0.68	GO:0042562	hormone binding
0.45	GO:0004867	serine-type endopeptidase inhibitor activity

0.73	GO:0005615	extracellular space
0.45	GO:0005581	collagen trimer
0.41	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q96RP7|G3ST4_HUMAN
Galactose-3-O-sulfotransferase 4
Search

GAL3ST4

0.97	Galactose-3-O-sulfotransferase 4

0.73	GO:0009247	glycolipid biosynthetic process
0.42	GO:0009101	glycoprotein biosynthetic process
0.38	GO:0006681	galactosylceramide metabolic process
0.38	GO:0046513	ceramide biosynthetic process
0.37	GO:0006029	proteoglycan metabolic process
0.37	GO:0042552	myelination
0.37	GO:0007283	spermatogenesis
0.36	GO:0007267	cell-cell signaling
0.36	GO:0009311	oligosaccharide metabolic process
0.35	GO:0006790	sulfur compound metabolic process

0.85	GO:0050694	galactose 3-O-sulfotransferase activity
0.40	GO:0050698	proteoglycan sulfotransferase activity
0.39	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.32	GO:0043021	ribonucleoprotein complex binding

0.72	GO:0005794	Golgi apparatus
0.39	GO:0070062	extracellular exosome
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.33	GO:0005730	nucleolus
0.33	GO:0030687	preribosome, large subunit precursor
0.32	GO:0005654	nucleoplasm
0.32	GO:0005694	chromosome
0.32	GO:0005887	integral component of plasma membrane

0.85

GO:0050694

sp|Q96RP8|KCNA7_HUMAN
Potassium voltage-gated channel subfamily A member 7
Search

0.79	Potassium voltage-gated channel protein Shaker

0.75	GO:0051260	protein homooligomerization
0.75	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.42	GO:0007637	proboscis extension reflex
0.42	GO:0048047	mating behavior, sex discrimination
0.42	GO:0060025	regulation of synaptic activity
0.42	GO:1903351	cellular response to dopamine
0.42	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.42	GO:0045838	positive regulation of membrane potential
0.41	GO:0008345	larval locomotory behavior

0.78	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.34	GO:0030424	axon

sp|Q96RP9|EFGM_HUMAN
Elongation factor G, mitochondrial
Search

GFM1

0.70	Elongation factor G, mitochondrial

0.80

GO:0070125

mitochondrial translational elongation

0.69	GO:0003746	translation elongation factor activity
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.33	GO:0005515	protein binding

0.57	GO:0005739	mitochondrion
0.36	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|Q96RQ1|ERGI2_HUMAN
Endoplasmic reticulum-Golgi intermediate compartment protein 2
Search

ERGIC2

0.93	Endoplasmic reticulum-Golgi intermediate compartment

0.58	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.37	GO:0006888	ER to Golgi vesicle-mediated transport

0.34

GO:0005515

protein binding

0.55	GO:0005730	nucleolus
0.41	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.38	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005794	Golgi apparatus
0.38	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RQ3|MCCA_HUMAN
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
Search

MCCC1

0.83	Methylcrotonoyl-CoA carboxylase subunit alpha

0.39	GO:0006552	leucine catabolic process
0.35	GO:0051291	protein heterooligomerization
0.35	GO:0035023	regulation of Rho protein signal transduction
0.34	GO:0006768	biotin metabolic process
0.34	GO:0065009	regulation of molecular function
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0006811	ion transport
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.76	GO:0004075	biotin carboxylase activity
0.56	GO:0004485	methylcrotonoyl-CoA carboxylase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.35	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0033293	monocarboxylic acid binding
0.34	GO:0033218	amide binding

0.59	GO:1905202	methylcrotonoyl-CoA carboxylase complex
0.50	GO:0005759	mitochondrial matrix
0.43	GO:0031090	organelle membrane
0.42	GO:0005740	mitochondrial envelope
0.36	GO:0005764	lysosome
0.36	GO:0044437	vacuolar part
0.36	GO:0098805	whole membrane
0.34	GO:0005829	cytosol
0.33	GO:0015935	small ribosomal subunit
0.33	GO:0005576	extracellular region

0.76	EC:6.3.4.14	GO:0004075
0.56	KEGG:R04138	GO:0004485

sp|Q96RQ9|OXLA_HUMAN
L-amino-acid oxidase
Search

IL4I1

0.69	Interleukin 4 induced 1

0.53

GO:0055114

oxidation-reduction process

0.54

GO:0016491

oxidoreductase activity

0.54

GO:0016491

sp|Q96RR1|PEO1_HUMAN
Twinkle protein, mitochondrial
Search

TWNK

0.86	Progressive external ophthalmoplegia 1

0.70	GO:0032392	DNA geometric change
0.66	GO:0006260	DNA replication
0.60	GO:0032042	mitochondrial DNA metabolic process
0.60	GO:0034214	protein hexamerization
0.59	GO:0006390	mitochondrial transcription
0.54	GO:0051260	protein homooligomerization
0.41	GO:0071333	cellular response to glucose stimulus
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.34	GO:0051301	cell division
0.34	GO:0051603	proteolysis involved in cellular protein catabolic process

0.71	GO:0003678	DNA helicase activity
0.57	GO:0002020	protease binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003697	single-stranded DNA binding
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.32	GO:0020037	heme binding
0.32	GO:0009055	electron transfer activity

0.57	GO:0042645	mitochondrial nucleoid
0.34	GO:0030126	COPI vesicle coat
0.34	GO:0005839	proteasome core complex
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RR4|KKCC2_HUMAN
Calcium/calmodulin-dependent protein kinase kinase 2
Search

CAMKK2

0.95	Calcium/calmodulin-dependent protein kinase kinase 2 beta

0.63	GO:0006468	protein phosphorylation
0.61	GO:0061762	CAMKK-AMPK signaling cascade
0.54	GO:0001934	positive regulation of protein phosphorylation
0.47	GO:0018210	peptidyl-threonine modification
0.46	GO:0018209	peptidyl-serine modification
0.45	GO:0033674	positive regulation of kinase activity
0.45	GO:0045859	regulation of protein kinase activity
0.36	GO:1903599	positive regulation of autophagy of mitochondrion
0.35	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0034614	cellular response to reactive oxygen species

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005509	calcium ion binding
0.46	GO:0005516	calmodulin binding
0.35	GO:0030295	protein kinase activator activity

0.49	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.36	GO:0042995	cell projection

sp|Q96RS0|TGS1_HUMAN
Trimethylguanosine synthase
Search

TGS1

0.89	Trimethylguanosine synthase

0.73	GO:0036260	RNA capping
0.67	GO:0001510	RNA methylation
0.39	GO:0071167	ribonucleoprotein complex import into nucleus
0.37	GO:0000387	spliceosomal snRNP assembly
0.36	GO:0019216	regulation of lipid metabolic process
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:0010468	regulation of gene expression
0.35	GO:0090022	regulation of neutrophil chemotaxis

0.68	GO:0071164	RNA trimethylguanosine synthase activity
0.34	GO:0005515	protein binding

0.53	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.37	GO:0005615	extracellular space
0.36	GO:0120114	Sm-like protein family complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

sp|Q96RS6|NUDC1_HUMAN
NudC domain-containing protein 1
Search

NUDCD1

0.96	Chronic myelogenous leukemia tumor antigen 66

0.39

GO:0002376

immune system process

0.37	GO:0005515	protein binding
0.35	GO:0005509	calcium ion binding

0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RT1|ERBIN_HUMAN
Erbin
Search

0.76	Putative cytoskeletal regulator flightless-i

0.85	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.61	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
0.61	GO:0007165	signal transduction
0.60	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.59	GO:0032495	response to muramyl dipeptide
0.57	GO:0071356	cellular response to tumor necrosis factor
0.56	GO:0032496	response to lipopolysaccharide
0.50	GO:0006605	protein targeting
0.38	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.37	GO:0045175	basal protein localization

0.86	GO:0005176	ErbB-2 class receptor binding
0.48	GO:0005178	integrin binding
0.36	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0004385	guanylate kinase activity
0.35	GO:0005200	structural constituent of cytoskeleton

0.60	GO:0030056	hemidesmosome
0.57	GO:0016323	basolateral plasma membrane
0.54	GO:0016607	nuclear speck
0.40	GO:0005737	cytoplasm
0.37	GO:0031965	nuclear membrane
0.36	GO:0045178	basal part of cell
0.36	GO:0008328	ionotropic glutamate receptor complex
0.36	GO:0005604	basement membrane
0.36	GO:0014069	postsynaptic density
0.35	GO:0045211	postsynaptic membrane

0.35

EC:2.7.4.8

GO:0004385

sp|Q96RT6|CTGE2_HUMAN
cTAGE family member 2
Search

0.84	CTAGE family member 5, ER export factor

0.30

GO:0044425

membrane part

sp|Q96RT7|GCP6_HUMAN
Gamma-tubulin complex component 6
Search

TUBGCP6

0.69	Tubulin gamma complex associated protein 6

0.81	GO:0007020	microtubule nucleation
0.48	GO:0090307	mitotic spindle assembly
0.48	GO:0051298	centrosome duplication
0.48	GO:0031122	cytoplasmic microtubule organization
0.46	GO:0051321	meiotic cell cycle
0.36	GO:0071526	semaphorin-plexin signaling pathway
0.36	GO:0000165	MAPK cascade
0.35	GO:0016569	covalent chromatin modification
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.82	GO:0043015	gamma-tubulin binding
0.52	GO:0008017	microtubule binding
0.46	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0017154	semaphorin receptor activity
0.36	GO:0004707	MAP kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016787	hydrolase activity

0.79	GO:0000922	spindle pole
0.76	GO:0005815	microtubule organizing center
0.52	GO:0005874	microtubule
0.47	GO:0032155	cell division site part
0.45	GO:0043234	protein complex
0.43	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:2.7.11.24	GO:0004707
0.36	KEGG:R00162	GO:0004707

sp|Q96RT8|GCP5_HUMAN
Gamma-tubulin complex component 5
Search

TUBGCP5

0.64	Gamma-tubulin complex component

0.81	GO:0007020	microtubule nucleation
0.48	GO:0090307	mitotic spindle assembly
0.48	GO:0051298	centrosome duplication
0.48	GO:0031122	cytoplasmic microtubule organization
0.46	GO:0051321	meiotic cell cycle

0.82	GO:0043015	gamma-tubulin binding
0.52	GO:0008017	microtubule binding
0.46	GO:0005200	structural constituent of cytoskeleton

0.79	GO:0000922	spindle pole
0.76	GO:0005815	microtubule organizing center
0.72	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.47	GO:0032155	cell division site part
0.45	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q96RU2|UBP28_HUMAN
Ubiquitin carboxyl-terminal hydrolase 28
Search

USP28

0.89	Ubiquitin carboxyl-terminal hydrolase 28

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.57	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.56	GO:0000077	DNA damage checkpoint
0.55	GO:0034644	cellular response to UV
0.55	GO:0010212	response to ionizing radiation
0.54	GO:0007265	Ras protein signal transduction
0.53	GO:0008283	cell proliferation
0.53	GO:0031647	regulation of protein stability
0.44	GO:0021551	central nervous system morphogenesis

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.37	GO:0051117	ATPase binding
0.37	GO:0031625	ubiquitin protein ligase binding

0.52	GO:0016604	nuclear body
0.44	GO:0043234	protein complex
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0005829	cytosol
0.34	GO:0000775	chromosome, centromeric region
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:3.4.19.12

GO:0036459

sp|Q96RU3|FNBP1_HUMAN
Formin-binding protein 1
Search

FNBP1

0.84	Formin-binding protein 1

0.71	GO:0006897	endocytosis
0.36	GO:0007399	nervous system development
0.36	GO:0030154	cell differentiation
0.35	GO:0061024	membrane organization

0.59	GO:0042802	identical protein binding
0.41	GO:0008289	lipid binding

0.43	GO:0005905	clathrin-coated pit
0.42	GO:0005764	lysosome
0.41	GO:0005938	cell cortex
0.41	GO:0031410	cytoplasmic vesicle
0.40	GO:0005856	cytoskeleton
0.37	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol

sp|Q96RU7|TRIB3_HUMAN
Tribbles homolog 3
Search

TRIB3

0.95	Tribbles pseudokinase 3

0.63	GO:0006468	protein phosphorylation
0.63	GO:0045599	negative regulation of fat cell differentiation
0.62	GO:0010558	negative regulation of macromolecule biosynthetic process
0.62	GO:0031327	negative regulation of cellular biosynthetic process
0.61	GO:0051172	negative regulation of nitrogen compound metabolic process
0.56	GO:0032270	positive regulation of cellular protein metabolic process
0.56	GO:0010827	regulation of glucose transport
0.55	GO:0032092	positive regulation of protein binding
0.55	GO:0045922	negative regulation of fatty acid metabolic process
0.55	GO:0032869	cellular response to insulin stimulus

0.67	GO:0003714	transcription corepressor activity
0.63	GO:0004672	protein kinase activity
0.60	GO:0055106	ubiquitin-protein transferase regulator activity
0.58	GO:0031625	ubiquitin protein ligase binding
0.55	GO:0019901	protein kinase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0008134	transcription factor binding
0.42	GO:0004860	protein kinase inhibitor activity

0.52	GO:0031965	nuclear membrane
0.49	GO:0005730	nucleolus
0.36	GO:0005856	cytoskeleton
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

sp|Q96RU8|TRIB1_HUMAN
Tribbles homolog 1
Search

TRIB1

0.56	Tribbles pseudokinase 1

0.63	GO:0006468	protein phosphorylation
0.62	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.61	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.60	GO:0014912	negative regulation of smooth muscle cell migration
0.60	GO:0045645	positive regulation of eosinophil differentiation
0.59	GO:0045659	negative regulation of neutrophil differentiation
0.59	GO:0048662	negative regulation of smooth muscle cell proliferation
0.58	GO:0043405	regulation of MAP kinase activity
0.57	GO:0045651	positive regulation of macrophage differentiation
0.57	GO:0043433	negative regulation of DNA binding transcription factor activity

0.64	GO:0004672	protein kinase activity
0.63	GO:0031434	mitogen-activated protein kinase kinase binding
0.60	GO:0055106	ubiquitin-protein transferase regulator activity
0.58	GO:0004860	protein kinase inhibitor activity
0.58	GO:0031625	ubiquitin protein ligase binding
0.56	GO:0008134	transcription factor binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008270	zinc ion binding

0.47	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.36	GO:0005856	cytoskeleton

sp|Q96RV3|PCX1_HUMAN
Pecanex-like protein 1
Search

PCNX1

0.97	Pecanex homolog (Drosophila)

0.30

GO:0044425

membrane part

sp|Q96RW7|HMCN1_HUMAN
Hemicentin-1
Search

HMCN1

0.47	Hemicentin 1

0.50	GO:0033334	fin morphogenesis
0.49	GO:0071711	basement membrane organization
0.44	GO:0035335	peptidyl-tyrosine dephosphorylation
0.40	GO:0006939	smooth muscle contraction
0.39	GO:0030335	positive regulation of cell migration
0.35	GO:0007155	cell adhesion
0.34	GO:0006508	proteolysis
0.33	GO:0090497	mesenchymal cell migration
0.33	GO:0033338	medial fin development
0.33	GO:0043589	skin morphogenesis

0.70	GO:0005509	calcium ion binding
0.44	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0008237	metallopeptidase activity

0.56	GO:0005604	basement membrane
0.53	GO:0005938	cell cortex
0.52	GO:0030054	cell junction
0.35	GO:0070062	extracellular exosome
0.33	GO:0032154	cleavage furrow
0.30	GO:0016020	membrane

0.44

GO:0004725

sp|Q96RY5|CRML_HUMAN
Protein cramped-like
Search

CRAMP1

0.97	Cramped chromatin regulator homolog 1

0.33	GO:0014706	striated muscle tissue development
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0007275	multicellular organism development
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.51	GO:0003682	chromatin binding
0.36	GO:0003677	DNA binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0016874	ligase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.33

GO:0004725

sp|Q96RY7|IF140_HUMAN
Intraflagellar transport protein 140 homolog
Search

IFT140

0.96	Intraflagellar transport protein 140

0.69	GO:0035721	intraciliary retrograde transport
0.68	GO:1990403	embryonic brain development
0.68	GO:0035845	photoreceptor cell outer segment organization
0.66	GO:0061512	protein localization to cilium
0.66	GO:0021532	neural tube patterning
0.66	GO:0031076	embryonic camera-type eye development
0.65	GO:1902017	regulation of cilium assembly
0.65	GO:0042733	embryonic digit morphogenesis
0.65	GO:0008589	regulation of smoothened signaling pathway
0.65	GO:0048701	embryonic cranial skeleton morphogenesis

0.30

GO:0003824

catalytic activity

0.76	GO:0005929	cilium
0.68	GO:0030991	intraciliary transport particle A
0.64	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.60	GO:0005815	microtubule organizing center
0.60	GO:0043005	neuron projection

sp|Q96S06|LMF1_HUMAN
Lipase maturation factor 1
Search

LMF1

0.78	Lipase maturation factor

0.57	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.57	GO:0051006	positive regulation of lipoprotein lipase activity
0.56	GO:0033578	protein glycosylation in Golgi
0.56	GO:0090181	regulation of cholesterol metabolic process
0.55	GO:0090207	regulation of triglyceride metabolic process
0.52	GO:0006641	triglyceride metabolic process
0.51	GO:0051604	protein maturation
0.51	GO:0006888	ER to Golgi vesicle-mediated transport
0.47	GO:0009306	protein secretion

0.33

GO:0005515

protein binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|Q96S07|PRR25_HUMAN
Proline-rich protein 25
Search

PRR25

0.97	Proline-rich protein 25

sp|Q96S15|WDR24_HUMAN
WD repeat-containing protein 24
Search

WDR24

0.93	WD repeat-containing protein 24

0.80	GO:0032008	positive regulation of TOR signaling
0.57	GO:0034198	cellular response to amino acid starvation
0.51	GO:0010506	regulation of autophagy
0.40	GO:0006914	autophagy
0.33	GO:0007042	lysosomal lumen acidification
0.33	GO:0030307	positive regulation of cell growth
0.33	GO:1903432	regulation of TORC1 signaling
0.33	GO:0031331	positive regulation of cellular catabolic process

0.34

GO:0005515

protein binding

0.57	GO:0061700	GATOR2 complex
0.55	GO:0005765	lysosomal membrane
0.33	GO:0044754	autolysosome

sp|Q96S16|JMJD8_HUMAN
JmjC domain-containing protein 8
Search

JMJD8

0.97	Jumonji domain containing 8

sp|Q96S19|CP013_HUMAN
UPF0585 protein C16orf13
Search

METTL26

0.97	Methyltransferase like 26

0.53	GO:0032259	methylation
0.38	GO:0006508	proteolysis

0.53	GO:0008168	methyltransferase activity
0.40	GO:0004252	serine-type endopeptidase activity

0.30

GO:0044425

membrane part

0.53

GO:0008168

sp|Q96S21|RB40C_HUMAN
Ras-related protein Rab-40C
Search

RAB40C

0.90	SOCS box-containing protein RAR3 (Fragment)

0.66	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.46	GO:0072659	protein localization to plasma membrane
0.46	GO:0017157	regulation of exocytosis
0.45	GO:0006904	vesicle docking involved in exocytosis
0.42	GO:0009306	protein secretion
0.41	GO:1990967	multi-organism toxin transport
0.35	GO:0001881	receptor recycling
0.35	GO:0042552	myelination
0.33	GO:0010951	negative regulation of endopeptidase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0005515	protein binding

0.46	GO:0030667	secretory granule membrane
0.45	GO:0008021	synaptic vesicle
0.44	GO:0005768	endosome
0.41	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005886	plasma membrane
0.38	GO:0005635	nuclear envelope
0.33	GO:0005576	extracellular region

sp|Q96S37|S22AC_HUMAN
Solute carrier family 22 member 12
Search

SLC22A12

0.97	Solute carrier family 22 member 9

0.68	GO:0015747	urate transport
0.62	GO:0046415	urate metabolic process
0.56	GO:0043252	sodium-independent organic anion transport
0.54	GO:0055085	transmembrane transport
0.50	GO:0042493	response to drug
0.49	GO:0015698	inorganic anion transport
0.38	GO:0097744	urate salt excretion
0.36	GO:0015913	short-chain fatty acid import
0.36	GO:0032869	cellular response to insulin stimulus
0.35	GO:0065008	regulation of biological quality

0.68	GO:0015143	urate transmembrane transporter activity
0.59	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.58	GO:0030165	PDZ domain binding
0.56	GO:0005452	inorganic anion exchanger activity
0.36	GO:0015636	short-chain fatty acid transmembrane transporter activity
0.35	GO:0015301	anion:anion antiporter activity

0.60	GO:0016324	apical plasma membrane
0.48	GO:0005887	integral component of plasma membrane
0.45	GO:0009897	external side of plasma membrane
0.41	GO:0031526	brush border membrane
0.40	GO:0070062	extracellular exosome
0.35	GO:0016323	basolateral plasma membrane

sp|Q96S38|KS6C1_HUMAN
Ribosomal protein S6 kinase delta-1
Search

RPS6KC1

0.97	Ribosomal protein S6 kinase delta-1

0.63	GO:0006468	protein phosphorylation
0.41	GO:0007165	signal transduction
0.31	GO:0055114	oxidation-reduction process

0.71	GO:0035091	phosphatidylinositol binding
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.32	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.32	GO:0005507	copper ion binding

0.55	GO:0005769	early endosome
0.34	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.32

EC:1.14.17

GO:0016715

sp|Q96S42|NODAL_HUMAN
Nodal homolog
Search

NODAL

0.97	Nodal growth differentiation factor

0.76	GO:0010469	regulation of receptor activity
0.67	GO:0048382	mesendoderm development
0.67	GO:0060802	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
0.67	GO:0090010	transforming growth factor beta receptor signaling pathway involved in primitive streak formation
0.67	GO:0033505	floor plate morphogenesis
0.66	GO:0048322	axial mesodermal cell fate commitment
0.66	GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry
0.66	GO:1901383	negative regulation of chorionic trophoblast cell proliferation
0.66	GO:0060460	left lung morphogenesis
0.66	GO:0001831	trophectodermal cellular morphogenesis

0.78	GO:0008083	growth factor activity
0.66	GO:0070698	type I activin receptor binding
0.52	GO:0005160	transforming growth factor beta receptor binding
0.50	GO:0005125	cytokine activity
0.39	GO:0016015	morphogen activity

0.66

GO:0005576

extracellular region

sp|Q96S44|PRPK_HUMAN
TP53-regulating kinase
Search

TP53RK

0.93	TP53-regulating kinase

0.63	GO:0006468	protein phosphorylation
0.47	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process
0.36	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0008033	tRNA processing
0.33	GO:0042357	thiamine diphosphate metabolic process
0.33	GO:0042723	thiamine-containing compound metabolic process
0.33	GO:0072528	pyrimidine-containing compound biosynthetic process
0.33	GO:0044272	sulfur compound biosynthetic process
0.33	GO:0009108	coenzyme biosynthetic process
0.32	GO:0090407	organophosphate biosynthetic process

0.70	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0002039	p53 binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004788	thiamine diphosphokinase activity
0.33	GO:0016787	hydrolase activity
0.33	GO:1901681	sulfur compound binding
0.33	GO:0019842	vitamin binding
0.32	GO:0016875	ligase activity, forming carbon-oxygen bonds

0.59	GO:0000408	EKC/KEOPS complex
0.47	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004674

sp|Q96S52|PIGS_HUMAN
GPI transamidase component PIG-S
Search

PIGS

0.90	Phosphatidylinositol glycan anchor biosynthesis class S

0.83	GO:0016255	attachment of GPI anchor to protein
0.32	GO:0015074	DNA integration

0.61	GO:0003923	GPI-anchor transamidase activity
0.34	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.81

GO:0042765

GPI-anchor transamidase complex

0.61

GO:0003923

sp|Q96S53|TESK2_HUMAN
Dual specificity testis-specific protein kinase 2
Search

TESK2

0.96	LOW QUALITY PROTEIN: dual specificity testis-specific protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.42	GO:0048041	focal adhesion assembly
0.41	GO:0035556	intracellular signal transduction
0.40	GO:0007283	spermatogenesis
0.38	GO:0030036	actin cytoskeleton organization
0.38	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0006915	apoptotic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004871	signal transducer activity
0.37	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.56	GO:0016604	nuclear body
0.37	GO:0005737	cytoplasm

sp|Q96S55|WRIP1_HUMAN
ATPase WRNIP1
Search

WRNIP1

0.96	Werner helicase interacting protein 1

0.66	GO:0006260	DNA replication
0.64	GO:0000731	DNA synthesis involved in DNA repair
0.64	GO:0030174	regulation of DNA-dependent DNA replication initiation
0.34	GO:0032392	DNA geometric change
0.33	GO:0006310	DNA recombination

0.58	GO:0042802	identical protein binding
0.55	GO:0003677	DNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0017111	nucleoside-triphosphatase activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0140097	catalytic activity, acting on DNA

0.63	GO:0000784	nuclear chromosome, telomeric region
0.62	GO:0048471	perinuclear region of cytoplasm

0.54

EC:3.6.1.15

GO:0017111

sp|Q96S59|RANB9_HUMAN
Ran-binding protein 9
Search

RANBP9

0.95	Ran-binding protein 9

0.85	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.41	GO:0048731	system development
0.41	GO:0007020	microtubule nucleation
0.40	GO:0000165	MAPK cascade
0.40	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.40	GO:0000904	cell morphogenesis involved in differentiation
0.40	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0006935	chemotaxis
0.38	GO:0006928	movement of cell or subcellular component
0.38	GO:0065009	regulation of molecular function

0.71	GO:0019899	enzyme binding
0.38	GO:0098772	molecular function regulator

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.42	GO:0015630	microtubule cytoskeleton
0.41	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane

sp|Q96S65|CSRN1_HUMAN
Cysteine/serine-rich nuclear protein 1
Search

CSRNP1

0.96	Cysteine and serine rich nuclear protein 1

0.79	GO:0060325	face morphogenesis
0.79	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.77	GO:0060021	palate development
0.74	GO:0048705	skeletal system morphogenesis
0.72	GO:0006366	transcription by RNA polymerase II
0.71	GO:0009791	post-embryonic development
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0030901	midbrain development
0.49	GO:0021536	diencephalon development
0.48	GO:0010923	negative regulation of phosphatase activity

0.76	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.62	GO:0043565	sequence-specific DNA binding
0.36	GO:0005515	protein binding
0.35	GO:0005248	voltage-gated sodium channel activity

0.59	GO:0005634	nucleus
0.35	GO:0001518	voltage-gated sodium channel complex

sp|Q96S66|CLCC1_HUMAN
Chloride channel CLIC-like protein 1
Search

CLCC1

0.97	Chloride channel CLIC like 1

0.41

GO:1902476

chloride transmembrane transport

0.41

GO:0005254

chloride channel activity

0.56	GO:0005783	endoplasmic reticulum
0.42	GO:0034707	chloride channel complex
0.40	GO:0005794	Golgi apparatus
0.37	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion

sp|Q96S79|RSLAB_HUMAN
Ras-like protein family member 10B
Search

RASL10B

0.97	RAS like family 10 member B

0.61	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide
0.61	GO:0007165	signal transduction
0.57	GO:0090277	positive regulation of peptide hormone secretion
0.34	GO:0045943	positive regulation of transcription by RNA polymerase I
0.32	GO:0006886	intracellular protein transport
0.32	GO:0016192	vesicle-mediated transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.35	GO:0005730	nucleolus
0.34	GO:0005886	plasma membrane
0.33	GO:0030131	clathrin adaptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q96S82|UBL7_HUMAN
Ubiquitin-like protein 7
Search

UBL7

0.94	Ubiquitin like 7

0.48

GO:0005515

protein binding

sp|Q96S86|HPLN3_HUMAN
Hyaluronan and proteoglycan link protein 3
Search

HAPLN3

0.93	Hyaluronan and proteoglycan link protein 3

0.72	GO:0007155	cell adhesion
0.50	GO:0001501	skeletal system development
0.49	GO:0007417	central nervous system development
0.39	GO:0031101	fin regeneration
0.35	GO:0008065	establishment of blood-nerve barrier
0.35	GO:0002040	sprouting angiogenesis
0.34	GO:0085029	extracellular matrix assembly

0.84	GO:0005540	hyaluronic acid binding
0.50	GO:0005201	extracellular matrix structural constituent
0.35	GO:0005509	calcium ion binding
0.33	GO:0042802	identical protein binding

0.49	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q96S90|LYSM1_HUMAN
LysM and putative peptidoglycan-binding domain-containing protein 1
Search

LYSMD1

0.93	LysM and peptidoglycan-binding domain-containing protein 1

0.35	GO:0006368	transcription elongation from RNA polymerase II promoter
0.34	GO:0016570	histone modification

0.37

GO:0005515

protein binding

0.69	GO:0005654	nucleoplasm
0.34	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.33	GO:0043234	protein complex

sp|Q96S94|CCNL2_HUMAN
Cyclin-L2
Search

0.63	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.54	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.53	GO:1904031	positive regulation of cyclin-dependent protein kinase activity
0.51	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.50	GO:0045787	positive regulation of cell cycle
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0006396	RNA processing
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:0045862	positive regulation of proteolysis
0.32	GO:0043043	peptide biosynthetic process

0.52	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.37	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.52	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.32	GO:0005840	ribosome

0.52

GO:0016538

sp|Q96S95|CK2N2_HUMAN
Calcium/calmodulin-dependent protein kinase II inhibitor 2
Search

CAMK2N2

0.96	Calcium/calmodulin-dependent protein kinase II inhibitor 2

0.81	GO:0006469	negative regulation of protein kinase activity
0.48	GO:0016310	phosphorylation
0.47	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.46	GO:1904029	regulation of cyclin-dependent protein kinase activity
0.45	GO:0008285	negative regulation of cell proliferation
0.44	GO:0045786	negative regulation of cell cycle
0.44	GO:0045861	negative regulation of proteolysis
0.43	GO:0010628	positive regulation of gene expression
0.36	GO:0048167	regulation of synaptic plasticity
0.34	GO:0007268	chemical synaptic transmission

0.83	GO:0004860	protein kinase inhibitor activity
0.66	GO:0010858	calcium-dependent protein kinase regulator activity
0.53	GO:0019901	protein kinase binding
0.50	GO:0016301	kinase activity

0.52	GO:0005813	centrosome
0.47	GO:0014069	postsynaptic density
0.45	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.39	GO:0045211	postsynaptic membrane
0.38	GO:0043005	neuron projection
0.38	GO:0030054	cell junction
0.38	GO:0043025	neuronal cell body
0.37	GO:0120038	plasma membrane bounded cell projection part

sp|Q96S96|PEBP4_HUMAN
Phosphatidylethanolamine-binding protein 4
Search

PEBP4

0.97	Phosphatidylethanolamine-binding protein 4

0.81	GO:0048573	photoperiodism, flowering
0.79	GO:0009909	regulation of flower development
0.56	GO:0048572	short-day photoperiodism
0.55	GO:0048506	regulation of timing of meristematic phase transition
0.55	GO:0010229	inflorescence development
0.43	GO:0009617	response to bacterium
0.37	GO:0090344	negative regulation of cell aging
0.37	GO:0009744	response to sucrose
0.36	GO:0048581	negative regulation of post-embryonic development
0.36	GO:0006623	protein targeting to vacuole

0.82	GO:0008429	phosphatidylethanolamine binding
0.40	GO:0005515	protein binding
0.35	GO:0003712	transcription cofactor activity
0.33	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding

0.47	GO:0005764	lysosome
0.45	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q96S97|MYADM_HUMAN
Myeloid-associated differentiation marker
Search

MYADM

0.94	Myeloid associated differentiation marker

0.59	GO:0090038	negative regulation of protein kinase C signaling
0.59	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.57	GO:0061028	establishment of endothelial barrier
0.57	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.56	GO:0031579	membrane raft organization
0.55	GO:0072659	protein localization to plasma membrane
0.54	GO:0030837	negative regulation of actin filament polymerization
0.54	GO:0030335	positive regulation of cell migration
0.51	GO:0001933	negative regulation of protein phosphorylation
0.48	GO:0010629	negative regulation of gene expression

0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0001726	ruffle
0.54	GO:0030864	cortical actin cytoskeleton
0.54	GO:0045121	membrane raft
0.52	GO:0005911	cell-cell junction
0.42	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q96S99|PKHF1_HUMAN
Pleckstrin homology domain-containing family F member 1
Search

PLEKHF1

0.95	Pleckstrin homology and FYVE domain containing 1

0.56	GO:0007032	endosome organization
0.55	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.55	GO:0072659	protein localization to plasma membrane
0.53	GO:0010508	positive regulation of autophagy
0.38	GO:0006915	apoptotic process
0.35	GO:0046902	regulation of mitochondrial membrane permeability
0.35	GO:0015031	protein transport

0.58	GO:0010314	phosphatidylinositol-5-phosphate binding
0.55	GO:0070273	phosphatidylinositol-4-phosphate binding
0.55	GO:0032266	phosphatidylinositol-3-phosphate binding
0.53	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.55	GO:0031410	cytoplasmic vesicle
0.53	GO:0005764	lysosome
0.52	GO:0012505	endomembrane system
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0005634	nucleus
0.35	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion

sp|Q96SA4|SERC2_HUMAN
Serine incorporator 2
Search

SERINC2

0.88	Serine incorporator 2

0.77	GO:0006658	phosphatidylserine metabolic process
0.72	GO:0006665	sphingolipid metabolic process
0.51	GO:0015825	L-serine transport
0.44	GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.44	GO:1904222	positive regulation of serine C-palmitoyltransferase activity
0.40	GO:0006487	protein N-linked glycosylation
0.35	GO:0044091	membrane biogenesis
0.33	GO:0008654	phospholipid biosynthetic process

0.51	GO:0015194	L-serine transmembrane transporter activity
0.37	GO:0030674	protein binding, bridging
0.34	GO:0019899	enzyme binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.37	GO:1990234	transferase complex
0.37	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q96SB3|NEB2_HUMAN
Neurabin-2
Search

PPP1R9B

0.86	Neurabin-2

0.77	GO:0050804	modulation of chemical synaptic transmission
0.72	GO:0042127	regulation of cell proliferation
0.60	GO:2000474	regulation of opioid receptor signaling pathway
0.59	GO:0071315	cellular response to morphine
0.56	GO:0019722	calcium-mediated signaling
0.54	GO:0016358	dendrite development
0.52	GO:0007015	actin filament organization
0.49	GO:0031399	regulation of protein modification process
0.49	GO:0019220	regulation of phosphate metabolic process
0.43	GO:1904372	positive regulation of protein localization to actin cortical patch

0.82	GO:0008157	protein phosphatase 1 binding
0.70	GO:0003779	actin binding
0.43	GO:0031749	D2 dopamine receptor binding
0.42	GO:0044325	ion channel binding
0.41	GO:0004864	protein phosphatase inhibitor activity
0.41	GO:0008022	protein C-terminus binding
0.40	GO:0019900	kinase binding
0.40	GO:0032403	protein complex binding
0.36	GO:0004672	protein kinase activity
0.35	GO:0019904	protein domain specific binding

0.58	GO:0030175	filopodium
0.55	GO:0030864	cortical actin cytoskeleton
0.48	GO:0043197	dendritic spine
0.42	GO:0031252	cell leading edge
0.41	GO:0030426	growth cone
0.41	GO:0014069	postsynaptic density
0.41	GO:0031253	cell projection membrane
0.41	GO:0043025	neuronal cell body
0.39	GO:0030054	cell junction
0.39	GO:0097060	synaptic membrane

sp|Q96SB4|SRPK1_HUMAN
SRSF protein kinase 1
Search

SRPK1

0.91	SRSF protein kinase 1

0.62	GO:0006468	protein phosphorylation
0.60	GO:0045070	positive regulation of viral genome replication
0.60	GO:0045071	negative regulation of viral genome replication
0.55	GO:0050684	regulation of mRNA processing
0.53	GO:0007059	chromosome segregation
0.48	GO:0035556	intracellular signal transduction
0.48	GO:0000245	spliceosomal complex assembly
0.38	GO:0030154	cell differentiation
0.36	GO:0043484	regulation of RNA splicing
0.36	GO:0006997	nucleus organization

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0000287	magnesium ion binding
0.35	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0015116	sulfate transmembrane transporter activity

0.50	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q96SB8|SMC6_HUMAN
Structural maintenance of chromosomes protein 6
Search

0.77	GO:0000724	double-strand break repair via homologous recombination
0.60	GO:0090398	cellular senescence
0.59	GO:0000722	telomere maintenance via recombination
0.58	GO:0051984	positive regulation of chromosome segregation

0.55	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0030915	Smc5-Smc6 complex
0.61	GO:0035061	interchromatin granule
0.59	GO:0000803	sex chromosome
0.58	GO:0016605	PML body
0.57	GO:0035861	site of double-strand break
0.55	GO:0000781	chromosome, telomeric region
0.37	GO:0016607	nuclear speck

sp|Q96SC8|DMTA2_HUMAN
Doublesex- and mab-3-related transcription factor A2
Search

DMRTA2

0.96	Doublesex- and mab-3-related transcription factor A2

0.64	GO:0021796	cerebral cortex regionalization
0.63	GO:0002052	positive regulation of neuroblast proliferation
0.62	GO:0071542	dopaminergic neuron differentiation
0.62	GO:0048665	neuron fate specification
0.61	GO:0035914	skeletal muscle cell differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.35	GO:0060128	corticotropin hormone secreting cell differentiation
0.33	GO:0006366	transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0042803	protein homodimerization activity
0.55	GO:0046982	protein heterodimerization activity
0.53	GO:0046872	metal ion binding
0.33	GO:0001012	RNA polymerase II regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|Q96SD1|DCR1C_HUMAN
Protein artemis
Search

DCLRE1C

0.97	DNA cross-link repair 1C

0.81	GO:0030183	B cell differentiation
0.79	GO:0010212	response to ionizing radiation
0.77	GO:0000723	telomere maintenance
0.74	GO:0006302	double-strand break repair
0.74	GO:0033151	V(D)J recombination
0.65	GO:0036297	interstrand cross-link repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.63	GO:0000726	non-recombinational repair
0.51	GO:0002250	adaptive immune response

0.79	GO:0000014	single-stranded DNA endodeoxyribonuclease activity
0.76	GO:0008409	5'-3' exonuclease activity
0.60	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.58	GO:0003684	damaged DNA binding
0.37	GO:0005515	protein binding

0.85	GO:0070419	nonhomologous end joining complex
0.68	GO:0005794	Golgi apparatus
0.67	GO:0031981	nuclear lumen
0.63	GO:0000781	chromosome, telomeric region

0.60

EC:3.1.11

GO:0016895

sp|Q96SE0|ABHD1_HUMAN
Protein ABHD1
Search

ABHD1

0.91	abhydrolase domain-containing protein 1

0.46	GO:0044255	cellular lipid metabolic process
0.43	GO:0097164	ammonium ion metabolic process
0.38	GO:0019637	organophosphate metabolic process
0.37	GO:0006796	phosphate-containing compound metabolic process
0.36	GO:1901564	organonitrogen compound metabolic process

0.51	GO:0016298	lipase activity
0.45	GO:0052689	carboxylic ester hydrolase activity
0.34	GO:0005515	protein binding

0.30

GO:0031224

intrinsic component of membrane

0.51	EC:3.1.1	GO:0016298
0.45	KEGG:R00630	GO:0052689

sp|Q96SE7|ZN347_HUMAN
Zinc finger protein 347
Search

ZNF347

0.65	Zinc finger protein 28

0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression
0.40	GO:0097659	nucleic acid-templated transcription
0.39	GO:0010467	gene expression
0.38	GO:0034645	cellular macromolecule biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part

sp|Q96SF2|TCPQM_HUMAN
T-complex protein 1 subunit theta-like 2
Search

CCT8L2

0.94	Chaperonin containing TCP1 subunit 8 like 2

0.63	GO:0006457	protein folding
0.37	GO:1904869	regulation of protein localization to Cajal body
0.36	GO:1904851	positive regulation of establishment of protein localization to telomere
0.36	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.36	GO:0007339	binding of sperm to zona pellucida
0.36	GO:0032212	positive regulation of telomere maintenance via telomerase
0.36	GO:1900182	positive regulation of protein localization to nucleus
0.36	GO:0071805	potassium ion transmembrane transport
0.35	GO:1901998	toxin transport
0.35	GO:0050821	protein stabilization

0.65	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0044183	protein binding involved in protein folding
0.37	GO:0015269	calcium-activated potassium channel activity
0.37	GO:0031681	G-protein beta-subunit binding
0.36	GO:0005253	anion channel activity
0.36	GO:0048487	beta-tubulin binding
0.36	GO:0003730	mRNA 3'-UTR binding

0.51	GO:0005832	chaperonin-containing T-complex
0.36	GO:0002199	zona pellucida receptor complex
0.36	GO:0043209	myelin sheath
0.35	GO:0044297	cell body
0.35	GO:0005813	centrosome
0.35	GO:0005730	nucleolus
0.35	GO:0005874	microtubule

0.33

EC:1.2.4.1

GO:0004739

sp|Q96SF7|TBX15_HUMAN
T-box transcription factor TBX15
Search

TBX15

0.94	T-box containing transcription factor

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.45	GO:0048701	embryonic cranial skeleton morphogenesis
0.41	GO:0051253	negative regulation of RNA metabolic process
0.41	GO:0010558	negative regulation of macromolecule biosynthetic process
0.41	GO:0031327	negative regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0003677	DNA binding
0.46	GO:0001106	RNA polymerase II transcription corepressor activity
0.43	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.44	GO:0017053	transcriptional repressor complex
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part

sp|Q96SI1|KCD15_HUMAN
BTB/POZ domain-containing protein KCTD15
Search

KCTD15

0.92	BTB/POZ domain-containing protein KCTD15

0.78	GO:0051260	protein homooligomerization
0.41	GO:0007275	multicellular organism development
0.36	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.36	GO:0060070	canonical Wnt signaling pathway
0.36	GO:0048863	stem cell differentiation
0.35	GO:0009888	tissue development

0.45

GO:0042802

identical protein binding

0.35

GO:0005654

nucleoplasm

sp|Q96SI9|STRBP_HUMAN
Spermatid perinuclear RNA-binding protein
Search

STRBP

0.97	Spermatid perinuclear RNA-binding protein isoform A

0.78	GO:0007283	spermatogenesis
0.57	GO:0007638	mechanosensory behavior
0.53	GO:0007281	germ cell development
0.39	GO:0007275	multicellular organism development

0.58	GO:0003723	RNA binding
0.36	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.49	GO:0015630	microtubule cytoskeleton
0.45	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

sp|Q96SJ8|TSN18_HUMAN
Tetraspanin-18
Search

TSPAN18

0.59	Tetraspanin

0.44

GO:0007166

cell surface receptor signaling pathway

0.42

GO:0005887

integral component of plasma membrane

sp|Q96SK2|TM209_HUMAN
Transmembrane protein 209
Search

TMEM209

0.97	Transmembrane protein 209

0.30

GO:0044425

membrane part

sp|Q96SK3|ZN607_HUMAN
Zinc finger protein 607
Search

0.66	Zinc finger protein 30

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.51	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.39	GO:0006369	termination of RNA polymerase II transcription

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding

0.49	GO:0015030	Cajal body
0.36	GO:0031965	nuclear membrane

sp|Q96SL1|DIRC2_HUMAN
Disrupted in renal carcinoma protein 2
Search

DIRC2

0.97	LOW QUALITY PROTEIN: disrupted in renal carcinoma protein 2

0.43

GO:0055085

transmembrane transport

0.44	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.36	GO:0044446	intracellular organelle part
0.36	GO:0044444	cytoplasmic part
0.30	GO:0044425	membrane part

sp|Q96SL4|GPX7_HUMAN
Glutathione peroxidase 7
Search

GPX7

0.48	Glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.33	GO:0033554	cellular response to stress
0.32	GO:0006468	protein phosphorylation

0.79	GO:0004602	glutathione peroxidase activity
0.53	GO:0004096	catalase activity
0.33	GO:0005515	protein binding
0.32	GO:0004672	protein kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005783	endoplasmic reticulum
0.36	GO:0005576	extracellular region
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.79

EC:1.11.1.9

GO:0004602

sp|Q96SL8|FIZ1_HUMAN
Flt3-interacting zinc finger protein 1
Search

FIZ1

0.84	Flt3-interacting zinc finger protein 1

0.56	GO:0001934	positive regulation of protein phosphorylation
0.41	GO:2001141	regulation of RNA biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.41	GO:0035914	skeletal muscle cell differentiation
0.38	GO:0006351	transcription, DNA-templated
0.34	GO:0045332	phospholipid translocation

0.61	GO:0030971	receptor tyrosine kinase binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004012	phospholipid-translocating ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.34	GO:0005876	spindle microtubule
0.30	GO:0016020	membrane

0.34

EC:3.6.3.1

GO:0004012

sp|Q96SM3|CPXM1_HUMAN
Probable carboxypeptidase X1
Search

CPXM1

0.97	Carboxypeptidase X, M14 family member 1

0.58	GO:0006508	proteolysis
0.45	GO:0051604	protein maturation
0.41	GO:0006518	peptide metabolic process

0.74	GO:0004181	metallocarboxypeptidase activity
0.61	GO:0008270	zinc ion binding
0.46	GO:0004185	serine-type carboxypeptidase activity

0.53	GO:0005615	extracellular space
0.35	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.74

EC:3.4.17

GO:0004181

sp|Q96SN7|ORAI2_HUMAN
Protein orai-2
Search

ORAI2

0.97	ORAI calcium release-activated calcium modulator 2

0.61	GO:0002115	store-operated calcium entry
0.50	GO:0070588	calcium ion transmembrane transport
0.47	GO:0070509	calcium ion import
0.46	GO:0061180	mammary gland epithelium development
0.40	GO:0051928	positive regulation of calcium ion transport
0.39	GO:0002250	adaptive immune response

0.56	GO:0015279	store-operated calcium channel activity
0.36	GO:0005516	calmodulin binding
0.36	GO:0042802	identical protein binding

0.46	GO:0016323	basolateral plasma membrane
0.42	GO:0005829	cytosol
0.39	GO:0043234	protein complex
0.38	GO:0030426	growth cone
0.37	GO:0005776	autophagosome
0.37	GO:0005887	integral component of plasma membrane
0.35	GO:0031410	cytoplasmic vesicle

sp|Q96SN8|CK5P2_HUMAN
CDK5 regulatory subunit-associated protein 2
Search

CDK5RAP2

0.82	CDK5 regulatory subunit-associated protein 2

0.64	GO:1903504	regulation of mitotic spindle checkpoint
0.63	GO:0046600	negative regulation of centriole replication
0.63	GO:0031116	positive regulation of microtubule polymerization
0.62	GO:0007099	centriole replication
0.62	GO:0000132	establishment of mitotic spindle orientation
0.62	GO:0001578	microtubule bundle formation
0.60	GO:0045665	negative regulation of neuron differentiation
0.58	GO:0007420	brain development
0.56	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0007059	chromosome segregation

0.60	GO:0043015	gamma-tubulin binding
0.59	GO:0005516	calmodulin binding
0.58	GO:0019901	protein kinase binding
0.57	GO:0044212	transcription regulatory region DNA binding
0.56	GO:0008017	microtubule binding

0.76	GO:0005815	microtubule organizing center
0.64	GO:0035371	microtubule plus-end
0.62	GO:0097431	mitotic spindle pole
0.59	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0030054	cell junction
0.55	GO:0005794	Golgi apparatus
0.47	GO:0043234	protein complex
0.38	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.34	GO:0005578	proteinaceous extracellular matrix

sp|Q96SQ5|ZN587_HUMAN
Zinc finger protein 587
Search

0.72	Zinc finger protein interacting with K protein 1

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.49	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.48	GO:0046872	metal ion binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0005515	protein binding

0.42	GO:0005622	intracellular
0.38	GO:0019013	viral nucleocapsid
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:1990904	ribonucleoprotein complex

sp|Q96SQ7|ATOH8_HUMAN
Protein atonal homolog 8
Search

ATOH8

0.94	Atonal bHLH transcription factor 8

0.72	GO:0030154	cell differentiation
0.61	GO:0045603	positive regulation of endothelial cell differentiation
0.60	GO:0051450	myoblast proliferation
0.59	GO:0001937	negative regulation of endothelial cell proliferation
0.59	GO:0060395	SMAD protein signal transduction
0.58	GO:0010595	positive regulation of endothelial cell migration
0.57	GO:0035148	tube formation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0070888	E-box binding
0.56	GO:0033613	activating transcription factor binding
0.36	GO:0005179	hormone activity

0.50	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q96SQ9|CP2S1_HUMAN
Cytochrome P450 2S1
Search

CYP2B

0.97	Cytochrome P450 family 2 subfamily S member 1

0.52	GO:0055114	oxidation-reduction process
0.50	GO:0019373	epoxygenase P450 pathway
0.40	GO:0042738	exogenous drug catabolic process
0.39	GO:0006805	xenobiotic metabolic process
0.37	GO:0008202	steroid metabolic process
0.37	GO:0042180	cellular ketone metabolic process
0.36	GO:0090420	naphthalene-containing compound metabolic process
0.34	GO:0009636	response to toxic substance

0.76	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.62	GO:0020037	heme binding
0.62	GO:0005506	iron ion binding
0.51	GO:0008395	steroid hydroxylase activity
0.50	GO:0008392	arachidonic acid epoxygenase activity
0.36	GO:0019825	oxygen binding

0.50	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:1.14.14

GO:0016712

sp|Q96SR6|ZN382_HUMAN
Zinc finger protein 382
Search

ZNF33A

0.85	Zinc finger protein 84

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0006351	transcription, DNA-templated
0.36	GO:0001558	regulation of cell growth

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|Q96ST2|IWS1_HUMAN
Protein IWS1 homolog
Search

sp|Q96ST3|SIN3A_HUMAN
Paired amphipathic helix protein Sin3a
Search

SIN3A

0.92	Transcription co-repressor Sin3

0.71	GO:1903507	negative regulation of nucleic acid-templated transcription
0.70	GO:1901675	negative regulation of histone H3-K27 acetylation
0.66	GO:0042754	negative regulation of circadian rhythm
0.66	GO:0031937	positive regulation of chromatin silencing
0.65	GO:0002230	positive regulation of defense response to virus by host
0.65	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.65	GO:0051595	response to methylglyoxal
0.65	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.64	GO:0071333	cellular response to glucose stimulus
0.64	GO:1900181	negative regulation of protein localization to nucleus

0.81	GO:0003714	transcription corepressor activity
0.67	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.65	GO:0001103	RNA polymerase II repressing transcription factor binding
0.64	GO:0001102	RNA polymerase II activating transcription factor binding
0.63	GO:0033558	protein deacetylase activity
0.62	GO:0001104	RNA polymerase II transcription cofactor activity
0.59	GO:0003682	chromatin binding
0.58	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.49	GO:0003700	DNA binding transcription factor activity
0.47	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

0.85	GO:0016580	Sin3 complex
0.61	GO:0017053	transcriptional repressor complex
0.59	GO:0000776	kinetochore
0.57	GO:0005667	transcription factor complex

0.47

EC:3.5.1

GO:0016811

sp|Q96ST8|CEP89_HUMAN
Centrosomal protein of 89 kDa
Search

CEP89

0.95	Centrosomal protein of isoform A

0.79	GO:0060271	cilium assembly
0.77	GO:0098916	anterograde trans-synaptic signaling
0.75	GO:0007005	mitochondrion organization
0.37	GO:0140056	organelle localization by membrane tethering

0.36

GO:0005515

protein binding

0.82	GO:0005814	centriole
0.65	GO:0097539	ciliary transition fiber
0.62	GO:0097730	non-motile cilium
0.60	GO:0031514	motile cilium
0.60	GO:0000922	spindle pole
0.59	GO:0005813	centrosome
0.53	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane
0.39	GO:0005758	mitochondrial intermembrane space
0.30	GO:0016021	integral component of membrane

sp|Q96SU4|OSBL9_HUMAN
Oxysterol-binding protein-related protein 9
Search

OSBPL9

0.60	Oxysterol-binding protein-related protein 9

0.74	GO:0006869	lipid transport
0.61	GO:0006699	bile acid biosynthetic process
0.55	GO:0015850	organic hydroxy compound transport

0.72	GO:0008289	lipid binding
0.59	GO:0015248	sterol transporter activity

0.77	GO:0031902	late endosome membrane
0.67	GO:0005794	Golgi apparatus
0.58	GO:0005829	cytosol

sp|Q96SW2|CRBN_HUMAN
Protein cereblon
Search

CRBN

0.94

Cereblon

0.54	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.51	GO:0016567	protein ubiquitination
0.40	GO:0032463	negative regulation of protein homooligomerization
0.40	GO:0090073	positive regulation of protein homodimerization activity
0.39	GO:0034766	negative regulation of ion transmembrane transport
0.35	GO:0035118	embryonic pectoral fin morphogenesis
0.35	GO:0071600	otic vesicle morphogenesis
0.34	GO:0060173	limb development

0.52	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.58	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.50	GO:0005730	nucleolus
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q96SY0|VWA9_HUMAN
von Willebrand factor A domain-containing protein 9
Search

INTS14

0.96	LOW QUALITY PROTEIN: von Willebrand factor A domain-containing protein 9

0.48

GO:0042795

snRNA transcription by RNA polymerase II

0.52	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q96SZ4|ZSC10_HUMAN
Zinc finger and SCAN domain-containing protein 10
Search

ZSCAN10

0.66	Zinc finger and SCAN domain-containing protein 10

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.51	GO:0006351	transcription, DNA-templated
0.47	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0048863	stem cell differentiation
0.33	GO:0035019	somatic stem cell population maintenance
0.33	GO:0032259	methylation

0.56	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.33	GO:0008080	N-acetyltransferase activity
0.33	GO:0008168	methyltransferase activity

0.56	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005829	cytosol

0.33

GO:0008080

sp|Q96SZ5|AEDO_HUMAN
2-aminoethanethiol dioxygenase
Search

ADO

0.95	2-aminoethanethiol dioxygenase

0.53	GO:0055114	oxidation-reduction process
0.37	GO:0000098	sulfur amino acid catabolic process

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.45	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:1.13.11

GO:0016702

sp|Q96SZ6|CK5P1_HUMAN
CDK5 regulatory subunit-associated protein 1
Search

CDK5RAP1

0.95	LOW QUALITY PROTEIN: CDK5 regulatory subunit-associated protein 1

0.67	GO:0006400	tRNA modification
0.57	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.56	GO:0045903	positive regulation of translational fidelity
0.56	GO:0090646	mitochondrial tRNA processing
0.55	GO:0070131	positive regulation of mitochondrial translation
0.55	GO:1900864	mitochondrial RNA modification
0.50	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process
0.37	GO:0045664	regulation of neuron differentiation
0.37	GO:0007420	brain development
0.35	GO:0008283	cell proliferation

0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.59	GO:0035597	N6-isopentenyladenosine methylthiotransferase activity
0.38	GO:0032403	protein complex binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0019887	protein kinase regulator activity
0.34	GO:0046872	metal ion binding
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.48	GO:0005737	cytoplasm
0.41	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.33

GO:0016616

sp|Q96T17|MA7D2_HUMAN
MAP7 domain-containing protein 2
Search

MAP7D2

0.97	MAP7 domain containing 2 brain transcript variant 2

0.74	GO:0000226	microtubule cytoskeleton organization
0.37	GO:0031110	regulation of microtubule polymerization or depolymerization
0.34	GO:0006413	translational initiation

0.40	GO:0005198	structural molecule activity
0.34	GO:0003743	translation initiation factor activity

0.69

GO:0015630

microtubule cytoskeleton

sp|Q96T21|SEBP2_HUMAN
Selenocysteine insertion sequence-binding protein 2
Search

SECISBP2

0.97	SECIS binding protein 2

0.85	GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.83	GO:0021756	striatum development
0.79	GO:0001514	selenocysteine incorporation
0.72	GO:0048666	neuron development
0.42	GO:1904571	positive regulation of selenocysteine incorporation
0.35	GO:0045859	regulation of protein kinase activity
0.34	GO:0051301	cell division
0.34	GO:0007049	cell cycle

0.86	GO:0035368	selenocysteine insertion sequence binding
0.82	GO:0003730	mRNA 3'-UTR binding
0.72	GO:0043021	ribonucleoprotein complex binding
0.41	GO:0005515	protein binding
0.37	GO:0008135	translation factor activity, RNA binding
0.36	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.58	GO:0005739	mitochondrion
0.38	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.36

GO:0016538

sp|Q96T23|RSF1_HUMAN
Remodeling and spacing factor 1
Search

RSF1

0.94	Remodeling and spacing factor 1

0.64	GO:0016584	nucleosome positioning
0.63	GO:0043392	negative regulation of DNA binding
0.60	GO:0050434	positive regulation of viral transcription
0.59	GO:0006334	nucleosome assembly
0.58	GO:0006338	chromatin remodeling
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:1902680	positive regulation of RNA biosynthetic process
0.55	GO:1902679	negative regulation of RNA biosynthetic process

0.59	GO:0042393	histone binding
0.53	GO:0046872	metal ion binding
0.35	GO:0016887	ATPase activity

0.85	GO:0031213	RSF complex
0.54	GO:0005654	nucleoplasm
0.35	GO:0034709	methylosome
0.35	GO:0034715	pICln-Sm protein complex
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.6.1.3

GO:0016887

sp|Q96T25|ZIC5_HUMAN
Zinc finger protein ZIC 5
Search

ZIC5

0.85	Zinc finger protein ZIC 5

0.52	GO:0007420	brain development
0.51	GO:0061351	neural precursor cell proliferation
0.45	GO:0009790	embryo development
0.45	GO:0072175	epithelial tube formation
0.44	GO:0030154	cell differentiation
0.41	GO:0060606	tube closure
0.40	GO:0060070	canonical Wnt signaling pathway
0.40	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0060042	retina morphogenesis in camera-type eye
0.39	GO:0051960	regulation of nervous system development

0.51	GO:0003676	nucleic acid binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0046872	metal ion binding

0.40	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q96T37|RBM15_HUMAN
Putative RNA-binding protein 15
Search

RBM15

0.96	RNA binding motif protein 15

0.65	GO:0007221	positive regulation of transcription of Notch receptor target
0.63	GO:0060674	placenta blood vessel development
0.63	GO:0060412	ventricular septum morphogenesis
0.63	GO:0001569	branching involved in blood vessel morphogenesis
0.63	GO:0048536	spleen development
0.62	GO:0045638	negative regulation of myeloid cell differentiation
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0051260	protein homooligomerization
0.35	GO:0071805	potassium ion transmembrane transport

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.36	GO:0005249	voltage-gated potassium channel activity

0.60	GO:0016607	nuclear speck
0.36	GO:0031965	nuclear membrane
0.36	GO:0008076	voltage-gated potassium channel complex

sp|Q96T49|PP16B_HUMAN
Protein phosphatase 1 regulatory inhibitor subunit 16B
Search

PPP1R16B

0.97	LOW QUALITY PROTEIN: protein phosphatase 1 regulatory inhibitor subunit 16B-like

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.68	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.67	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.65	GO:0061028	establishment of endothelial barrier
0.63	GO:0035307	positive regulation of protein dephosphorylation
0.63	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.42	GO:0051489	regulation of filopodium assembly
0.31	GO:0009058	biosynthetic process

0.80	GO:0019888	protein phosphatase regulator activity
0.36	GO:0005515	protein binding
0.31	GO:0070279	vitamin B6 binding
0.31	GO:0050662	coenzyme binding
0.31	GO:0043168	anion binding
0.30	GO:0003824	catalytic activity

0.60	GO:0016607	nuclear speck
0.59	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0042995	cell projection
0.45	GO:0005886	plasma membrane
0.31	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q96T51|RUFY1_HUMAN
RUN and FYVE domain-containing protein 1
Search

RUFY1

0.92	RUN and FYVE domain-containing protein 1

0.55	GO:0030100	regulation of endocytosis
0.46	GO:0015031	protein transport
0.36	GO:0006897	endocytosis
0.35	GO:0006661	phosphatidylinositol biosynthetic process
0.34	GO:0006457	protein folding
0.31	GO:0043043	peptide biosynthetic process
0.31	GO:0044267	cellular protein metabolic process
0.31	GO:0010467	gene expression
0.31	GO:0009059	macromolecule biosynthetic process

0.58	GO:0042169	SH2 domain binding
0.55	GO:0017124	SH3 domain binding
0.52	GO:0046872	metal ion binding
0.49	GO:0008565	protein transporter activity
0.36	GO:0008289	lipid binding
0.34	GO:0051082	unfolded protein binding
0.31	GO:0003735	structural constituent of ribosome
0.30	GO:0003824	catalytic activity

0.54	GO:0016607	nuclear speck
0.52	GO:0005768	endosome
0.48	GO:0005829	cytosol
0.36	GO:0044433	cytoplasmic vesicle part
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.34	GO:0005783	endoplasmic reticulum
0.31	GO:0005840	ribosome

sp|Q96T52|IMP2L_HUMAN
Mitochondrial inner membrane protease subunit 2
Search

IMMP2L

0.73	Mitochondrial inner membrane protease subunit

0.82	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.79	GO:0006465	signal peptide processing
0.50	GO:0061300	cerebellum vasculature development
0.50	GO:0033108	mitochondrial respiratory chain complex assembly
0.49	GO:0030728	ovulation
0.48	GO:0001541	ovarian follicle development
0.46	GO:0008015	blood circulation
0.46	GO:0007283	spermatogenesis
0.46	GO:0007420	brain development
0.45	GO:0006801	superoxide metabolic process

0.67	GO:0008236	serine-type peptidase activity
0.36	GO:0004175	endopeptidase activity
0.33	GO:0003725	double-stranded RNA binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0003743	translation initiation factor activity

0.85	GO:0042720	mitochondrial inner membrane peptidase complex
0.30	GO:0016021	integral component of membrane

sp|Q96T53|MBOA4_HUMAN
Ghrelin O-acyltransferase
Search

MBOAT4

0.97	Membrane bound O-acyltransferase domain containing 4

0.77	GO:0018190	protein octanoylation
0.67	GO:0018209	peptidyl-serine modification
0.36	GO:2001256	regulation of store-operated calcium entry
0.34	GO:0032094	response to food

0.65

GO:0016412

serine O-acyltransferase activity

0.63

GO:0030176

integral component of endoplasmic reticulum membrane

0.65

GO:0016412

sp|Q96T54|KCNKH_HUMAN
Potassium channel subfamily K member 17
Search

KCNK17

0.95	Potassium two pore domain channel subfamily K member 17

0.71	GO:0071805	potassium ion transmembrane transport
0.51	GO:0030322	stabilization of membrane potential
0.37	GO:0034765	regulation of ion transmembrane transport

0.74	GO:0005267	potassium channel activity
0.51	GO:0022840	leak channel activity
0.36	GO:0022832	voltage-gated channel activity
0.36	GO:0022839	ion gated channel activity
0.36	GO:0008381	mechanosensitive ion channel activity
0.33	GO:0005515	protein binding

0.43

GO:0005887

integral component of plasma membrane

sp|Q96T55|KCNKG_HUMAN
Potassium channel subfamily K member 16
Search

KCNK16

0.96	Potassium two pore domain channel subfamily K member 16

0.71	GO:0071805	potassium ion transmembrane transport
0.48	GO:0030322	stabilization of membrane potential
0.35	GO:0034765	regulation of ion transmembrane transport

0.74	GO:0005267	potassium channel activity
0.48	GO:0022840	leak channel activity
0.35	GO:0022832	voltage-gated channel activity
0.35	GO:0022839	ion gated channel activity
0.35	GO:0008381	mechanosensitive ion channel activity
0.34	GO:0005515	protein binding

0.41

GO:0005887

integral component of plasma membrane

sp|Q96T58|MINT_HUMAN
Msx2-interacting protein
Search

SPEN

0.96	Spen, transcriptional regulator

0.58	GO:0050769	positive regulation of neurogenesis
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:0007219	Notch signaling pathway
0.37	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0016032	viral process
0.35	GO:0006351	transcription, DNA-templated

0.61	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.60	GO:0001085	RNA polymerase II transcription factor binding
0.59	GO:0003723	RNA binding
0.38	GO:0003714	transcription corepressor activity
0.37	GO:0003697	single-stranded DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.31	GO:0046872	metal ion binding

0.58	GO:0017053	transcriptional repressor complex
0.52	GO:0005654	nucleoplasm
0.41	GO:0070062	extracellular exosome

sp|Q96T59|CDRTF_HUMAN
CMT1A duplicated region transcript 15 protein
Search

sp|Q96T60|PNKP_HUMAN
Bifunctional polynucleotide phosphatase/kinase
Search

PNKP

0.88	Bifunctional polynucleotide phosphatase/kinase

0.69	GO:0010836	negative regulation of protein ADP-ribosylation
0.69	GO:0098506	polynucleotide 3' dephosphorylation
0.68	GO:0042769	DNA damage response, detection of DNA damage
0.67	GO:1904355	positive regulation of telomere capping
0.65	GO:0051973	positive regulation of telomerase activity
0.65	GO:0032212	positive regulation of telomere maintenance via telomerase
0.57	GO:0016310	phosphorylation
0.55	GO:0006979	response to oxidative stress
0.55	GO:0098504	DNA 3' dephosphorylation involved in DNA repair
0.48	GO:0009117	nucleotide metabolic process

0.69	GO:0046403	polynucleotide 3'-phosphatase activity
0.68	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
0.57	GO:0019201	nucleotide kinase activity
0.46	GO:0003690	double-stranded DNA binding
0.36	GO:0003684	damaged DNA binding
0.35	GO:0004519	endonuclease activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0005515	protein binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005730	nucleolus
0.38	GO:0005739	mitochondrion
0.36	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.69	EC:3.1.3.32	GO:0046403
0.68	KEGG:R03840	GO:0046404

sp|Q96T66|NMNA3_HUMAN
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
Search

NMNAT3

0.67	Nicotinamide-nucleotide adenylyltransferase

0.71	GO:0009435	NAD biosynthetic process
0.56	GO:0009611	response to wounding
0.52	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate
0.44	GO:1990966	ATP generation from poly-ADP-D-ribose
0.34	GO:0006776	vitamin A metabolic process
0.34	GO:0002138	retinoic acid biosynthetic process

0.81	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity
0.76	GO:0004515	nicotinate-nucleotide adenylyltransferase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0042802	identical protein binding
0.35	GO:0008289	lipid binding

0.45	GO:0005739	mitochondrion
0.41	GO:0016604	nuclear body
0.33	GO:0005829	cytosol

0.81

EC:2.7.7.1

GO:0000309

sp|Q96T68|SETB2_HUMAN
Histone-lysine N-methyltransferase SETDB2
Search

SETDB2

0.97	SET domain bifurcated protein 2 variant B

0.77	GO:0034968	histone lysine methylation
0.62	GO:0061647	histone H3-K9 modification
0.55	GO:0000278	mitotic cell cycle
0.53	GO:0007059	chromosome segregation
0.40	GO:0070986	left/right axis specification
0.39	GO:0001947	heart looping
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0051301	cell division
0.32	GO:0045454	cell redox homeostasis

0.77	GO:0018024	histone-lysine N-methyltransferase activity
0.62	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.64	GO:0005694	chromosome
0.60	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:2.1.1.43

GO:0018024

sp|Q96T75|DSCR8_HUMAN
Down syndrome critical region protein 8
Search

DSCR8

0.97	Down syndrome critical region protein 8

0.63

GO:0005515

protein binding

sp|Q96T76|MMS19_HUMAN
MMS19 nucleotide excision repair protein homolog
Search

MMS19

0.92	MMS19 homolog, cytosolic iron-sulfur assembly component

0.72	GO:0016226	iron-sulfur cluster assembly
0.70	GO:0045893	positive regulation of transcription, DNA-templated
0.70	GO:0007059	chromosome segregation
0.63	GO:0006281	DNA repair
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:0009725	response to hormone
0.36	GO:0000160	phosphorelay signal transduction system

0.83	GO:0030331	estrogen receptor binding
0.75	GO:0003713	transcription coactivator activity
0.69	GO:0019899	enzyme binding
0.41	GO:0030159	receptor signaling complex scaffold activity
0.39	GO:0030674	protein binding, bridging

0.85	GO:0071817	MMXD complex
0.84	GO:0097361	CIA complex
0.67	GO:0005654	nucleoplasm
0.40	GO:0032806	carboxy-terminal domain protein kinase complex
0.39	GO:0090575	RNA polymerase II transcription factor complex
0.38	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.30	GO:0016020	membrane

sp|Q96T83|SL9A7_HUMAN
Sodium/hydrogen exchanger 7
Search

SLC9A7

0.62	Sodium/hydrogen exchanger

0.78	GO:0006885	regulation of pH
0.76	GO:0035725	sodium ion transmembrane transport
0.62	GO:1902600	hydrogen ion transmembrane transport
0.52	GO:0099587	inorganic ion import across plasma membrane
0.50	GO:0030004	cellular monovalent inorganic cation homeostasis
0.47	GO:0071805	potassium ion transmembrane transport
0.37	GO:0097484	dendrite extension
0.36	GO:0048675	axon extension
0.34	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway
0.34	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway

0.81	GO:0015385	sodium:proton antiporter activity
0.52	GO:0015386	potassium:proton antiporter activity
0.35	GO:0042803	protein homodimerization activity

0.51	GO:0055037	recycling endosome
0.44	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0005886	plasma membrane
0.39	GO:0010008	endosome membrane
0.37	GO:0031984	organelle subcompartment
0.36	GO:0005769	early endosome
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0044308	axonal spine
0.34	GO:0043679	axon terminus
0.34	GO:0030425	dendrite

sp|Q96T88|UHRF1_HUMAN
E3 ubiquitin-protein ligase UHRF1
Search

UHRF1

0.94	Ubiquitin like with PHD and ring finger domains 1

0.68	GO:0010216	maintenance of DNA methylation
0.64	GO:0010390	histone monoubiquitination
0.64	GO:0051865	protein autoubiquitination
0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0090308	regulation of methylation-dependent chromatin silencing
0.38	GO:0071158	positive regulation of cell cycle arrest
0.37	GO:0008283	cell proliferation
0.36	GO:0030154	cell differentiation

0.68	GO:0044729	hemi-methylated DNA-binding
0.65	GO:0031493	nucleosomal histone binding
0.62	GO:0035064	methylated histone binding
0.60	GO:0061630	ubiquitin protein ligase activity
0.56	GO:0042802	identical protein binding
0.53	GO:0046872	metal ion binding
0.33	GO:0016874	ligase activity

0.65	GO:0005720	nuclear heterochromatin
0.62	GO:0016363	nuclear matrix
0.56	GO:0005657	replication fork
0.36	GO:0005654	nucleoplasm

0.33

GO:0016874

sp|Q96T91|GPHA2_HUMAN
Glycoprotein hormone alpha-2
Search

GPHA2

0.84	Glycoprotein hormones alpha chain

0.75	GO:0010469	regulation of receptor activity
0.67	GO:0030819	positive regulation of cAMP biosynthetic process
0.65	GO:1903955	positive regulation of protein targeting to mitochondrion
0.56	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0006357	regulation of transcription by RNA polymerase II

0.79	GO:0005179	hormone activity
0.70	GO:0031531	thyrotropin-releasing hormone receptor binding
0.58	GO:0046982	protein heterodimerization activity
0.34	GO:0003677	DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q96T92|INSM2_HUMAN
Insulinoma-associated protein 2
Search

INSM2

0.93	INSM transcriptional repressor 2

0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0031536	positive regulation of exit from mitosis
0.35	GO:0055057	neuroblast division
0.35	GO:0001764	neuron migration
0.34	GO:0048666	neuron development
0.34	GO:0045165	cell fate commitment

0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.37	GO:0003714	transcription corepressor activity
0.34	GO:0001085	RNA polymerase II transcription factor binding
0.32	GO:0042826	histone deacetylase binding
0.32	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.32	GO:0030332	cyclin binding
0.32	GO:0003682	chromatin binding

0.38	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.32	GO:0017053	transcriptional repressor complex

sp|Q96TA0|PCDBI_HUMAN
Putative protocadherin beta-18
Search

0.93	Protocadherin beta-3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0007416	synapse assembly
0.59	GO:0098916	anterograde trans-synaptic signaling
0.50	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:0009988	cell-cell recognition

0.70	GO:0005509	calcium ion binding
0.39	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.42	GO:0032391	photoreceptor connecting cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q96TA1|NIBL1_HUMAN
Niban-like protein 1
Search

FAM129B

0.97	LOW QUALITY PROTEIN: niban-like protein 1

0.86	GO:0032274	gonadotropin secretion
0.86	GO:0034337	RNA folding
0.84	GO:2000679	positive regulation of transcription regulatory region DNA binding
0.83	GO:2000279	negative regulation of DNA biosynthetic process
0.76	GO:0008285	negative regulation of cell proliferation
0.75	GO:0043066	negative regulation of apoptotic process
0.70	GO:0045893	positive regulation of transcription, DNA-templated
0.69	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0044029	hypomethylation of CpG island
0.42	GO:0048743	positive regulation of skeletal muscle fiber development

0.78	GO:0045296	cadherin binding
0.76	GO:0003713	transcription coactivator activity

0.76	GO:0005912	adherens junction
0.68	GO:0005829	cytosol
0.67	GO:0005654	nucleoplasm
0.55	GO:0005886	plasma membrane
0.43	GO:0070062	extracellular exosome

sp|Q96TA2|YMEL1_HUMAN
ATP-dependent zinc metalloprotease YME1L1
Search

YME1L1

0.96	ATP-dependent zinc metalloprotease YME1L1

0.61	GO:0006508	proteolysis
0.54	GO:0035694	mitochondrial protein catabolic process
0.54	GO:0034214	protein hexamerization
0.50	GO:0008283	cell proliferation
0.49	GO:0043066	negative regulation of apoptotic process
0.47	GO:0051604	protein maturation
0.35	GO:0006851	mitochondrial calcium ion transmembrane transport
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process

0.70	GO:0004222	metalloendopeptidase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0004176	ATP-dependent peptidase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0000062	fatty-acyl-CoA binding
0.32	GO:0003735	structural constituent of ribosome

0.49	GO:0016604	nuclear body
0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

sp|Q96TC7|RMD3_HUMAN
Regulator of microtubule dynamics protein 3
Search

RMDN3

0.97	Regulator of microtubule dynamics protein 3

0.62	GO:0006874	cellular calcium ion homeostasis
0.43	GO:0006915	apoptotic process
0.42	GO:0030154	cell differentiation

0.35

GO:0005515

protein binding

0.61	GO:0005741	mitochondrial outer membrane
0.46	GO:0000922	spindle pole
0.43	GO:0005874	microtubule
0.39	GO:0005634	nucleus
0.35	GO:0072686	mitotic spindle
0.34	GO:0005794	Golgi apparatus
0.34	GO:0005829	cytosol
0.30	GO:0044425	membrane part

sp|Q99062|CSF3R_HUMAN
Granulocyte colony-stimulating factor receptor
Search

CSF3R

0.93	Colony stimulating factor 3 receptor

0.79	GO:0030593	neutrophil chemotaxis
0.79	GO:0019221	cytokine-mediated signaling pathway
0.76	GO:0045637	regulation of myeloid cell differentiation
0.40	GO:0097186	amelogenesis

0.85	GO:0051916	granulocyte colony-stimulating factor binding
0.81	GO:0004896	cytokine receptor activity

0.30

GO:0044425

membrane part

sp|Q99075|HBEGF_HUMAN
Proheparin-binding EGF-like growth factor
Search

HBEGF

0.97	Heparin binding EGF like growth factor

0.63	GO:0051549	positive regulation of keratinocyte migration
0.63	GO:0035313	wound healing, spreading of epidermal cells
0.62	GO:0007173	epidermal growth factor receptor signaling pathway
0.61	GO:0090303	positive regulation of wound healing
0.61	GO:0048661	positive regulation of smooth muscle cell proliferation
0.60	GO:0051897	positive regulation of protein kinase B signaling
0.59	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.58	GO:0008016	regulation of heart contraction
0.58	GO:0060326	cell chemotaxis
0.56	GO:0010469	regulation of receptor activity

0.62	GO:0005154	epidermal growth factor receptor binding
0.60	GO:0008201	heparin binding
0.58	GO:0008083	growth factor activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0051082	unfolded protein binding

0.55	GO:0009986	cell surface
0.55	GO:0005615	extracellular space
0.50	GO:0005887	integral component of plasma membrane
0.36	GO:0030669	clathrin-coated endocytic vesicle membrane
0.34	GO:0016272	prefoldin complex

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|Q99081|HTF4_HUMAN
Transcription factor 12
Search

TCF12

0.93	LOW QUALITY PROTEIN: transcription factor 12

0.56	GO:0045666	positive regulation of neuron differentiation
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0006366	transcription by RNA polymerase II
0.37	GO:1902036	regulation of hematopoietic stem cell differentiation
0.36	GO:0007517	muscle organ development
0.35	GO:0006955	immune response

0.67	GO:0046983	protein dimerization activity
0.58	GO:0070888	E-box binding
0.58	GO:0043425	bHLH transcription factor binding
0.55	GO:0046332	SMAD binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0042802	identical protein binding
0.42	GO:0071837	HMG box domain binding
0.41	GO:0035497	cAMP response element binding
0.37	GO:0035326	enhancer binding

0.54	GO:0016607	nuclear speck
0.52	GO:0005667	transcription factor complex
0.51	GO:0000790	nuclear chromatin
0.39	GO:0005737	cytoplasm

sp|Q99102|MUC4_HUMAN
Mucin-4
Search

MUC4

0.71

Mucin-4

0.80	GO:0007160	cell-matrix adhesion
0.41	GO:0002244	hematopoietic progenitor cell differentiation
0.39	GO:0002852	regulation of T cell mediated cytotoxicity directed against tumor cell target
0.39	GO:0002841	negative regulation of T cell mediated immune response to tumor cell
0.38	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.38	GO:0044849	estrous cycle
0.38	GO:0033189	response to vitamin A
0.38	GO:0031077	post-embryonic camera-type eye development
0.38	GO:0032570	response to progesterone
0.38	GO:0030277	maintenance of gastrointestinal epithelium

0.39	GO:0005509	calcium ion binding
0.38	GO:0005176	ErbB-2 class receptor binding
0.37	GO:0005520	insulin-like growth factor binding
0.36	GO:0032403	protein complex binding
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.34	GO:0005201	extracellular matrix structural constituent

0.39	GO:0005576	extracellular region
0.38	GO:0031528	microvillus membrane
0.37	GO:0016324	apical plasma membrane
0.36	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.36	GO:0031982	vesicle
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane
0.30	GO:0005794	Golgi apparatus
0.30	GO:0043233	organelle lumen
0.30	GO:0031226	intrinsic component of plasma membrane

sp|Q99217|AMELX_HUMAN
Amelogenin, X isoform
Search

0.86	Y-linked amelogenin

0.70	GO:0007275	multicellular organism development
0.48	GO:0009888	tissue development
0.46	GO:0009653	anatomical structure morphogenesis
0.37	GO:0010714	positive regulation of collagen metabolic process
0.37	GO:0032965	regulation of collagen biosynthetic process
0.37	GO:0051260	protein homooligomerization
0.37	GO:0042127	regulation of cell proliferation
0.37	GO:0010469	regulation of receptor activity
0.37	GO:0001649	osteoblast differentiation
0.37	GO:0051592	response to calcium ion

0.54	GO:0030345	structural constituent of tooth enamel
0.40	GO:0046848	hydroxyapatite binding
0.38	GO:0042802	identical protein binding
0.37	GO:0008083	growth factor activity
0.36	GO:0031402	sodium ion binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0046983	protein dimerization activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0009986	cell surface
0.36	GO:0030139	endocytic vesicle
0.36	GO:0044420	extracellular matrix component
0.36	GO:0099080	supramolecular complex
0.36	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0043234	protein complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q99218|AMELY_HUMAN
Amelogenin, Y isoform
Search

0.86	Y-linked amelogenin

0.70	GO:0007275	multicellular organism development
0.48	GO:0009888	tissue development
0.46	GO:0009653	anatomical structure morphogenesis
0.37	GO:0051260	protein homooligomerization
0.37	GO:0010714	positive regulation of collagen metabolic process
0.37	GO:0042127	regulation of cell proliferation
0.37	GO:0032965	regulation of collagen biosynthetic process
0.37	GO:0010469	regulation of receptor activity
0.37	GO:0051592	response to calcium ion
0.37	GO:0001649	osteoblast differentiation

0.55	GO:0030345	structural constituent of tooth enamel
0.40	GO:0046848	hydroxyapatite binding
0.38	GO:0042802	identical protein binding
0.37	GO:0008083	growth factor activity
0.36	GO:0031402	sodium ion binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0046983	protein dimerization activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0009986	cell surface
0.36	GO:0044420	extracellular matrix component
0.36	GO:0099080	supramolecular complex
0.36	GO:0030139	endocytic vesicle
0.36	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0043234	protein complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q99250|SCN2A_HUMAN
Sodium channel protein type 2 subunit alpha
Search

SCN2A

0.66	Sodium channel protein type 2 subunit alpha

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.56	GO:0019228	neuronal action potential
0.53	GO:0086010	membrane depolarization during action potential
0.53	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress
0.50	GO:0051402	neuron apoptotic process
0.47	GO:0098870	action potential propagation
0.47	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.47	GO:0086002	cardiac muscle cell action potential involved in contraction
0.47	GO:0050884	neuromuscular process controlling posture

0.84	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.35	GO:0043522	leucine zipper domain binding
0.34	GO:0031402	sodium ion binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.56	GO:0030315	T-tubule
0.55	GO:0014704	intercalated disc
0.55	GO:0044304	main axon
0.45	GO:0030018	Z disc
0.44	GO:0043025	neuronal cell body
0.44	GO:0016604	nuclear body

sp|Q99259|DCE1_HUMAN
Glutamate decarboxylase 1
Search

GAD1

0.52	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.57	GO:0035641	locomotory exploration behavior
0.56	GO:0035176	social behavior
0.46	GO:0042136	neurotransmitter biosynthetic process
0.39	GO:0016053	organic acid biosynthetic process
0.38	GO:0042493	response to drug
0.37	GO:1901566	organonitrogen compound biosynthetic process
0.36	GO:0018352	protein-pyridoxal-5-phosphate linkage
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.42	GO:0016595	glutamate binding
0.41	GO:0047485	protein N-terminus binding
0.39	GO:0046982	protein heterodimerization activity

0.57	GO:0060077	inhibitory synapse
0.55	GO:0043679	axon terminus
0.54	GO:0048786	presynaptic active zone
0.53	GO:0030424	axon
0.51	GO:0005938	cell cortex
0.44	GO:0005739	mitochondrion
0.36	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle
0.35	GO:0030665	clathrin-coated vesicle membrane
0.33	GO:0005886	plasma membrane

0.68

EC:4.1.1

GO:0016831

sp|Q99417|MYCBP_HUMAN
C-Myc-binding protein
Search

MYCBP

0.90	C-myc binding protein (Fragment)

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0007283	spermatogenesis
0.39	GO:0045880	positive regulation of smoothened signaling pathway
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0005978	glycogen biosynthetic process
0.34	GO:0034198	cellular response to amino acid starvation
0.33	GO:0071230	cellular response to amino acid stimulus
0.33	GO:1903432	regulation of TORC1 signaling

0.78	GO:0003713	transcription coactivator activity
0.34	GO:0003844	1,4-alpha-glucan branching enzyme activity
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0005515	protein binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.34	GO:0005922	connexin complex
0.34	GO:1990131	Gtr1-Gtr2 GTPase complex
0.33	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.34

EC:2.4.1.18

GO:0003844

sp|Q99418|CYH2_HUMAN
Cytohesin-2
Search

CYTH2

0.86	Putative pattern-formation protein/guanine nucleotide exchange factor (Fragment)

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.37	GO:0030155	regulation of cell adhesion
0.35	GO:2000171	negative regulation of dendrite development
0.34	GO:0090162	establishment of epithelial cell polarity
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0030036	actin cytoskeleton organization
0.34	GO:0098657	import into cell
0.34	GO:0007229	integrin-mediated signaling pathway
0.34	GO:0006813	potassium ion transport

0.82	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.40	GO:0070679	inositol 1,4,5 trisphosphate binding
0.38	GO:0008289	lipid binding
0.34	GO:0005242	inward rectifier potassium channel activity
0.34	GO:0005178	integrin binding

0.40	GO:0030426	growth cone
0.40	GO:0005886	plasma membrane
0.38	GO:0005923	bicellular tight junction
0.38	GO:0005912	adherens junction
0.37	GO:0005737	cytoplasm
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0001726	ruffle
0.34	GO:0031984	organelle subcompartment
0.34	GO:0012505	endomembrane system
0.34	GO:0098562	cytoplasmic side of membrane

sp|Q99424|ACOX2_HUMAN
Peroxisomal acyl-coenzyme A oxidase 2
Search

ACOX2

0.60	Acyl-coenzyme A oxidase

0.76	GO:0006635	fatty acid beta-oxidation
0.60	GO:1902884	positive regulation of response to oxidative stress
0.55	GO:0010942	positive regulation of cell death
0.36	GO:0006699	bile acid biosynthetic process
0.35	GO:0006692	prostanoid metabolic process
0.35	GO:0000038	very long-chain fatty acid metabolic process
0.35	GO:0007283	spermatogenesis
0.34	GO:0030041	actin filament polymerization
0.34	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.33	GO:0006091	generation of precursor metabolites and energy

0.82	GO:0003997	acyl-CoA oxidase activity
0.72	GO:0071949	FAD binding
0.65	GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
0.52	GO:0005102	receptor binding
0.46	GO:0003995	acyl-CoA dehydrogenase activity
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0005504	fatty acid binding
0.35	GO:0047485	protein N-terminus binding
0.35	GO:0030165	PDZ domain binding

0.75	GO:0005777	peroxisome
0.50	GO:0005829	cytosol
0.37	GO:0044438	microbody part
0.35	GO:0043233	organelle lumen
0.34	GO:0098805	whole membrane
0.34	GO:0005885	Arp2/3 protein complex
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0044428	nuclear part
0.33	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane

0.82

EC:1.3.3.6

GO:0003997

sp|Q99426|TBCB_HUMAN
Tubulin-folding cofactor B
Search

TBCB

0.81	Tubulin-specific chaperone B

0.48	GO:0031122	cytoplasmic microtubule organization
0.44	GO:0007399	nervous system development
0.43	GO:0030154	cell differentiation
0.39	GO:0010970	transport along microtubule
0.36	GO:0032781	positive regulation of ATPase activity
0.35	GO:0006418	tRNA aminoacylation for protein translation
0.34	GO:0034453	microtubule anchoring
0.34	GO:0006950	response to stress

0.41	GO:0005515	protein binding
0.37	GO:0044877	macromolecular complex binding
0.36	GO:0001671	ATPase activator activity
0.35	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.35	GO:0003723	RNA binding
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding

0.62	GO:0005829	cytosol
0.45	GO:0015630	microtubule cytoskeleton
0.44	GO:0044430	cytoskeletal part
0.43	GO:0099512	supramolecular fiber
0.38	GO:0015629	actin cytoskeleton
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.35

EC:6.1

GO:0016875

sp|Q99435|NELL2_HUMAN
Protein kinase C-binding protein NELL2
Search

NELL2

0.97	Neural EGFL like 2

0.70

GO:0005509

calcium ion binding

0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005623	cell

sp|Q99436|PSB7_HUMAN
Proteasome subunit beta type-7
Search

PSMB7

0.53	Proteasome subunit beta type

0.70	GO:0051603	proteolysis involved in cellular protein catabolic process
0.56	GO:1903955	positive regulation of protein targeting to mitochondrion
0.37	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.76	GO:0004298	threonine-type endopeptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.74	GO:0005839	proteasome core complex
0.57	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.35	GO:0101002	ficolin-1-rich granule
0.35	GO:0031983	vesicle lumen

0.76

EC:3.4.25

GO:0004298

sp|Q99437|VATO_HUMAN
V-type proton ATPase 21 kDa proteolipid subunit
Search

ATP6V0B

0.97	ATPase H+ transporting V0 subunit b

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.51	GO:0048066	developmental pigmentation
0.50	GO:0007035	vacuolar acidification
0.50	GO:0060041	retina development in camera-type eye

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.48	GO:0036442	proton-exporting ATPase activity
0.45	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.58	GO:0005768	endosome
0.47	GO:0044437	vacuolar part
0.30	GO:0031224	intrinsic component of membrane

sp|Q99439|CNN2_HUMAN
Calponin-2
Search

0.78

Calponin

0.82	GO:0031032	actomyosin structure organization
0.49	GO:0043535	regulation of blood vessel endothelial cell migration
0.47	GO:0043408	regulation of MAPK cascade
0.39	GO:0030855	epithelial cell differentiation
0.38	GO:0098609	cell-cell adhesion
0.37	GO:0032780	negative regulation of ATPase activity
0.35	GO:0006334	nucleosome assembly
0.33	GO:0055085	transmembrane transport
0.30	GO:0032940	secretion by cell
0.30	GO:0035722	interleukin-12-mediated signaling pathway

0.74	GO:0003779	actin binding
0.73	GO:0005516	calmodulin binding
0.41	GO:0098641	cadherin binding involved in cell-cell adhesion
0.36	GO:0030674	protein binding, bridging
0.36	GO:0008017	microtubule binding
0.35	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0005856	cytoskeleton
0.39	GO:0005913	cell-cell adherens junction
0.37	GO:0043197	dendritic spine
0.37	GO:0005829	cytosol
0.37	GO:0014069	postsynaptic density
0.37	GO:0005925	focal adhesion
0.37	GO:0043025	neuronal cell body
0.35	GO:0099512	supramolecular fiber
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005634	nucleus

sp|Q99440|CD006_HUMAN
Uncharacterized protein encoded by LINC01587
Search

sp|Q99442|SEC62_HUMAN
Translocation protein SEC62
Search

SEC62

0.82	Translocation protein 1

0.65	GO:0015031	protein transport
0.51	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.50	GO:0090150	establishment of protein localization to membrane
0.48	GO:0046907	intracellular transport
0.36	GO:0036498	IRE1-mediated unfolded protein response
0.33	GO:0060255	regulation of macromolecule metabolic process

0.36	GO:0004872	receptor activity
0.32	GO:0003677	DNA binding

0.77	GO:0030176	integral component of endoplasmic reticulum membrane
0.40	GO:0005791	rough endoplasmic reticulum
0.34	GO:0005829	cytosol

sp|Q99445|GML_HUMAN
Glycosyl-phosphatidylinositol-anchored molecule-like protein
Search

GML

0.97	Glycosylphosphatidylinositol anchored molecule like

sp|Q99447|PCY2_HUMAN
Ethanolamine-phosphate cytidylyltransferase
Search

PCYT2

0.84	Ethanolamine-phosphate cytidylyltransferase

0.49	GO:0009058	biosynthetic process
0.38	GO:0046337	phosphatidylethanolamine metabolic process

0.54	GO:0016779	nucleotidyltransferase activity
0.38	GO:0070403	NAD+ binding
0.33	GO:0003723	RNA binding

0.34

GO:0005789

endoplasmic reticulum membrane

0.54

GO:0016779

sp|Q99453|PHX2B_HUMAN
Paired mesoderm homeobox protein 2B
Search

PHOX2A

0.92	Paired mesoderm homeobox protein 2B

0.74	GO:0003357	noradrenergic neuron differentiation
0.70	GO:0048857	neural nucleus development
0.68	GO:0048485	sympathetic nervous system development
0.67	GO:0043576	regulation of respiratory gaseous exchange
0.67	GO:0030902	hindbrain development
0.67	GO:0048486	parasympathetic nervous system development
0.66	GO:0021545	cranial nerve development
0.63	GO:0021953	central nervous system neuron differentiation
0.61	GO:0003360	brainstem development
0.60	GO:1901166	neural crest cell migration involved in autonomic nervous system development

0.60	GO:0043565	sequence-specific DNA binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.57	GO:0000785	chromatin
0.53	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q99456|K1C12_HUMAN
Keratin, type I cytoskeletal 12
Search

KRT12

0.94	Keratin 10 (Epidermolytic hyperkeratosis; keratosis palmaris et plantaris)

0.49	GO:0030216	keratinocyte differentiation
0.45	GO:0018149	peptide cross-linking
0.43	GO:0045103	intermediate filament-based process
0.43	GO:0042633	hair cycle
0.43	GO:0007010	cytoskeleton organization
0.40	GO:0007568	aging
0.40	GO:0051546	keratinocyte migration
0.40	GO:0061436	establishment of skin barrier
0.39	GO:0002009	morphogenesis of an epithelium
0.39	GO:0030336	negative regulation of cell migration

0.62	GO:0005198	structural molecule activity
0.38	GO:0097110	scaffold protein binding
0.38	GO:1990254	keratin filament binding
0.37	GO:0032395	MHC class II receptor activity
0.36	GO:0042289	MHC class II protein binding
0.32	GO:0008092	cytoskeletal protein binding
0.31	GO:0003677	DNA binding

0.79	GO:0005882	intermediate filament
0.46	GO:0001533	cornified envelope
0.38	GO:0070062	extracellular exosome
0.37	GO:0045178	basal part of cell
0.37	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.34	GO:0016327	apicolateral plasma membrane
0.34	GO:0042383	sarcolemma
0.33	GO:0015629	actin cytoskeleton
0.33	GO:0036338	viral membrane

sp|Q99457|NP1L3_HUMAN
Nucleosome assembly protein 1-like 3
Search

NAP1L3

0.96	Nucleosome assembly protein 1 like 3

0.79

GO:0006334

nucleosome assembly

0.33

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.34	GO:0042470	melanosome

sp|Q99459|CDC5L_HUMAN
Cell division cycle 5-like protein
Search

CDC5L

0.94	Cell division cycle 5 like

0.57	GO:0072422	signal transduction involved in DNA damage checkpoint
0.56	GO:0051301	cell division
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0000398	mRNA splicing, via spliceosome
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0030154	cell differentiation
0.38	GO:1904567	response to wortmannin
0.38	GO:1990646	cellular response to prolactin
0.37	GO:0071352	cellular response to interleukin-2
0.37	GO:1990090	cellular response to nerve growth factor stimulus

0.61	GO:0071987	WD40-repeat domain binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.54	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.37	GO:0043522	leucine zipper domain binding
0.37	GO:0001222	transcription corepressor binding
0.37	GO:0008157	protein phosphatase 1 binding
0.36	GO:0019901	protein kinase binding
0.35	GO:0003723	RNA binding

0.58	GO:0005662	DNA replication factor A complex
0.57	GO:0071007	U2-type catalytic step 2 spliceosome
0.57	GO:0000974	Prp19 complex
0.54	GO:0016607	nuclear speck
0.39	GO:0005737	cytoplasm
0.34	GO:0000176	nuclear exosome (RNase complex)
0.30	GO:0016020	membrane

sp|Q99460|PSMD1_HUMAN
26S proteasome non-ATPase regulatory subunit 1
Search

PSMD1

0.90	26S proteasome non-ATPase regulatory subunit 1

0.74	GO:0042176	regulation of protein catabolic process
0.67	GO:0050790	regulation of catalytic activity
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.69	GO:0030234	enzyme regulator activity
0.41	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding

0.71	GO:1905369	endopeptidase complex
0.58	GO:0043234	protein complex
0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.34	GO:0012505	endomembrane system
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part
0.31	GO:0099023	tethering complex

sp|Q99463|NPY6R_HUMAN
Putative neuropeptide Y receptor type 6
Search

NPY1R

0.94	Neuropeptide Y receptor type 6

0.78	GO:0007218	neuropeptide signaling pathway
0.51	GO:0007631	feeding behavior
0.50	GO:0003151	outflow tract morphogenesis
0.49	GO:0008015	blood circulation
0.49	GO:0019233	sensory perception of pain
0.48	GO:0040014	regulation of multicellular organism growth
0.47	GO:0007626	locomotory behavior
0.44	GO:0006006	glucose metabolic process
0.43	GO:0007268	chemical synaptic transmission
0.41	GO:0065008	regulation of biological quality

0.82	GO:0004983	neuropeptide Y receptor activity
0.42	GO:0042923	neuropeptide binding

0.36	GO:0005886	plasma membrane
0.34	GO:0008021	synaptic vesicle
0.34	GO:0030424	axon
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q99466|NOTC4_HUMAN
Neurogenic locus notch homolog protein 4
Search

NOTCH4

0.73

Notch 4

0.81	GO:0007219	Notch signaling pathway
0.71	GO:0030154	cell differentiation
0.69	GO:0007275	multicellular organism development
0.67	GO:0050793	regulation of developmental process
0.52	GO:2001141	regulation of RNA biosynthetic process
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.47	GO:0003158	endothelium development
0.47	GO:0048646	anatomical structure formation involved in morphogenesis
0.46	GO:0042060	wound healing

0.70	GO:0005509	calcium ion binding
0.59	GO:0004872	receptor activity
0.44	GO:0005112	Notch binding
0.36	GO:0030695	GTPase regulator activity
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008270	zinc ion binding

0.56	GO:0009986	cell surface
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0031410	cytoplasmic vesicle
0.36	GO:0005634	nucleus
0.36	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.35	GO:0000139	Golgi membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0043235	receptor complex
0.35	GO:0005829	cytosol
0.35	GO:0070013	intracellular organelle lumen

sp|Q99467|CD180_HUMAN
CD180 antigen
Search

0.71	GO:0002322	B cell proliferation involved in immune response
0.70	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.70	GO:0071222	cellular response to lipopolysaccharide
0.59	GO:0002224	toll-like receptor signaling pathway
0.53	GO:0006952	defense response
0.49	GO:0042116	macrophage activation
0.48	GO:0050707	regulation of cytokine secretion
0.44	GO:0007166	cell surface receptor signaling pathway
0.37	GO:0032497	detection of lipopolysaccharide
0.36	GO:0045084	positive regulation of interleukin-12 biosynthetic process

0.50	GO:0001875	lipopolysaccharide receptor activity
0.44	GO:0004888	transmembrane signaling receptor activity
0.38	GO:0005515	protein binding
0.36	GO:0001530	lipopolysaccharide binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0046696	lipopolysaccharide receptor complex
0.46	GO:0005887	integral component of plasma membrane
0.35	GO:0009897	external side of plasma membrane
0.35	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0098857	membrane microdomain
0.33	GO:0005769	early endosome

sp|Q99469|STAC_HUMAN
SH3 and cysteine-rich domain-containing protein
Search

STAC

0.96	SH3 and cysteine rich domain

0.62	GO:0035556	intracellular signal transduction
0.58	GO:2001259	positive regulation of cation channel activity
0.58	GO:1903078	positive regulation of protein localization to plasma membrane
0.58	GO:1901385	regulation of voltage-gated calcium channel activity
0.55	GO:0006936	muscle contraction
0.54	GO:0034605	cellular response to heat

0.57	GO:0044325	ion channel binding
0.51	GO:0046872	metal ion binding

0.58	GO:0030315	T-tubule
0.44	GO:0005622	intracellular

sp|Q99470|SDF2_HUMAN
Stromal cell-derived factor 2
Search

SDF2

0.88	Stromal cell-derived factor 2

0.52	GO:0071712	ER-associated misfolded protein catabolic process
0.51	GO:0035269	protein O-linked mannosylation
0.35	GO:0042981	regulation of apoptotic process

0.51	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity
0.36	GO:0051787	misfolded protein binding
0.36	GO:0051117	ATPase binding
0.35	GO:0051087	chaperone binding

0.47	GO:0044432	endoplasmic reticulum part
0.46	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.38	GO:0043234	protein complex
0.36	GO:0005576	extracellular region
0.35	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.51

EC:2.4.1.109

GO:0004169

sp|Q99471|PFD5_HUMAN
Prefoldin subunit 5
Search

PFDN5

0.84	Prefoldin subunit

0.68	GO:0006457	protein folding
0.49	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.48	GO:0060041	retina development in camera-type eye
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.39	GO:0007021	tubulin complex assembly
0.38	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.33	GO:0006468	protein phosphorylation
0.32	GO:0006508	proteolysis

0.71	GO:0051082	unfolded protein binding
0.37	GO:0015631	tubulin binding
0.35	GO:0003714	transcription corepressor activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0008233	peptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0016272	prefoldin complex
0.39	GO:0051286	cell tip
0.38	GO:0032153	cell division site
0.37	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus

0.33

GO:0004674

sp|Q99487|PAFA2_HUMAN
Platelet-activating factor acetylhydrolase 2, cytoplasmic
Search

PAFAH2

0.92	Platelet-activating factor acetylhydrolase

0.71	GO:0016042	lipid catabolic process
0.46	GO:0034441	plasma lipoprotein particle oxidation
0.45	GO:0046469	platelet activating factor metabolic process
0.44	GO:0034374	low-density lipoprotein particle remodeling
0.44	GO:0090026	positive regulation of monocyte chemotaxis
0.41	GO:0034440	lipid oxidation
0.38	GO:0043066	negative regulation of apoptotic process
0.38	GO:0031110	regulation of microtubule polymerization or depolymerization
0.36	GO:0007596	blood coagulation
0.34	GO:0050729	positive regulation of inflammatory response

0.80	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.45	GO:0047499	calcium-independent phospholipase A2 activity
0.42	GO:0005543	phospholipid binding

0.44	GO:0034362	low-density lipoprotein particle
0.38	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.33	GO:0031966	mitochondrial membrane

0.80

EC:3.1.1.47

GO:0003847

sp|Q99489|OXDD_HUMAN
D-aspartate oxidase
Search

DDO

0.93	D-aspartate oxidase

0.76	GO:0046416	D-amino acid metabolic process
0.59	GO:0007625	grooming behavior
0.58	GO:0007320	insemination
0.55	GO:0006531	aspartate metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0042445	hormone metabolic process
0.49	GO:1901606	alpha-amino acid catabolic process
0.38	GO:0043649	dicarboxylic acid catabolic process
0.35	GO:0055085	transmembrane transport
0.32	GO:0034641	cellular nitrogen compound metabolic process

0.83	GO:0003884	D-amino-acid oxidase activity
0.73	GO:0071949	FAD binding
0.56	GO:0015922	aspartate oxidase activity
0.50	GO:0005102	receptor binding
0.34	GO:0022857	transmembrane transporter activity
0.32	GO:0046872	metal ion binding

0.48	GO:0005829	cytosol
0.38	GO:0005777	peroxisome
0.36	GO:0031907	microbody lumen
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.4.3.3

GO:0003884

sp|Q99490|AGAP2_HUMAN
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
Search

AGAP2

0.92	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

0.75	GO:0043547	positive regulation of GTPase activity
0.62	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.61	GO:0060749	mammary gland alveolus development
0.60	GO:0046427	positive regulation of JAK-STAT cascade
0.56	GO:0043066	negative regulation of apoptotic process
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:1901215	negative regulation of neuron death
0.42	GO:0043523	regulation of neuron apoptotic process
0.42	GO:1901099	negative regulation of signal transduction in absence of ligand
0.41	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.76	GO:0005096	GTPase activator activity
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.41	GO:0030295	protein kinase activator activity
0.40	GO:0019901	protein kinase binding
0.37	GO:0035014	phosphatidylinositol 3-kinase regulator activity

0.54	GO:0005730	nucleolus
0.47	GO:0005739	mitochondrion
0.38	GO:0070062	extracellular exosome
0.35	GO:0005768	endosome
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q99496|RING2_HUMAN
E3 ubiquitin-protein ligase RING2
Search

RNF2

0.79	Ring finger protein 2

0.86	GO:0036353	histone H2A-K119 monoubiquitination
0.85	GO:0001702	gastrulation with mouth forming second
0.84	GO:0009948	anterior/posterior axis specification
0.83	GO:0043433	negative regulation of DNA binding transcription factor activity
0.79	GO:0007281	germ cell development
0.77	GO:0000122	negative regulation of transcription by RNA polymerase II
0.74	GO:0000278	mitotic cell cycle

0.87	GO:0071535	RING-like zinc finger domain binding
0.76	GO:0003682	chromatin binding
0.76	GO:0061630	ubiquitin protein ligase activity
0.63	GO:0008270	zinc ion binding

0.86	GO:0001739	sex chromatin
0.85	GO:0035102	PRC1 complex
0.84	GO:0000791	euchromatin
0.82	GO:0071339	MLL1 complex
0.77	GO:0016604	nuclear body

sp|Q99497|PARK7_HUMAN
Protein DJ-1
Search

PARK7

0.96	Parkinsonism associated deglycase

0.85	GO:0140041	cellular detoxification of methylglyoxal
0.85	GO:0106044	guanine deglycation
0.84	GO:0036530	protein deglycation, methylglyoxal removal
0.84	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity
0.83	GO:0033864	positive regulation of NAD(P)H oxidase activity
0.82	GO:1903189	glyoxal metabolic process
0.82	GO:0036471	cellular response to glyoxal
0.82	GO:0010273	detoxification of copper ion
0.82	GO:1903178	positive regulation of tyrosine 3-monooxygenase activity
0.82	GO:0036528	peptidyl-lysine deglycation

0.82	GO:0036470	tyrosine 3-monooxygenase activator activity
0.82	GO:0036478	L-dopa decarboxylase activator activity
0.79	GO:0044388	small protein activating enzyme binding
0.78	GO:1903135	cupric ion binding
0.78	GO:0016532	superoxide dismutase copper chaperone activity
0.78	GO:1903136	cuprous ion binding
0.77	GO:1990381	ubiquitin-specific protease binding
0.76	GO:0050681	androgen receptor binding
0.75	GO:0036524	protein deglycase activity
0.75	GO:0097110	scaffold protein binding

0.73	GO:0016605	PML body
0.72	GO:0005913	cell-cell adherens junction
0.70	GO:0005747	mitochondrial respiratory chain complex I
0.69	GO:0044297	cell body
0.69	GO:0048471	perinuclear region of cytoplasm
0.68	GO:0098793	presynapse
0.68	GO:0005758	mitochondrial intermembrane space
0.67	GO:0043005	neuron projection
0.65	GO:0005759	mitochondrial matrix
0.63	GO:0000785	chromatin

0.64

EC:1.11.1.15

GO:0051920

sp|Q99500|S1PR3_HUMAN
Sphingosine 1-phosphate receptor 3
Search

S1PR3

0.97	Sphingosine 1-phosphate receptor

0.85	GO:0003376	sphingosine-1-phosphate signaling pathway
0.63	GO:1901551	negative regulation of endothelial cell development
0.61	GO:1903140	regulation of establishment of endothelial barrier
0.58	GO:0032651	regulation of interleukin-1 beta production
0.58	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.57	GO:0001816	cytokine production
0.55	GO:0007219	Notch signaling pathway
0.54	GO:0006954	inflammatory response
0.38	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis
0.38	GO:0034103	regulation of tissue remodeling

0.85	GO:0038036	sphingosine-1-phosphate receptor activity
0.58	GO:0005178	integrin binding
0.37	GO:0001664	G-protein coupled receptor binding
0.34	GO:0008289	lipid binding
0.34	GO:0070915	lysophosphatidic acid receptor activity
0.32	GO:0016491	oxidoreductase activity

0.44	GO:0005886	plasma membrane
0.36	GO:0009986	cell surface
0.36	GO:0098552	side of membrane
0.35	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.32

GO:0016491

sp|Q99501|GA2L1_HUMAN
GAS2-like protein 1
Search

GAS2L1

0.97	Growth arrest-specific 2 like 1

0.57	GO:0007026	negative regulation of microtubule depolymerization
0.56	GO:0045647	negative regulation of erythrocyte differentiation
0.55	GO:0097067	cellular response to thyroid hormone stimulus
0.55	GO:0001578	microtubule bundle formation
0.52	GO:0030308	negative regulation of cell growth
0.52	GO:0007050	cell cycle arrest
0.50	GO:0009267	cellular response to starvation
0.46	GO:0010629	negative regulation of gene expression

0.83	GO:0008093	cytoskeletal adaptor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0046966	thyroid hormone receptor binding
0.41	GO:0051015	actin filament binding

0.67	GO:0005856	cytoskeleton
0.50	GO:0099512	supramolecular fiber
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm

sp|Q99502|EYA1_HUMAN
Eyes absent homolog 1
Search

EYA1

0.75	Eyes absent homolog

0.84	GO:0042471	ear morphogenesis
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.57	GO:0016576	histone dephosphorylation
0.57	GO:0072513	positive regulation of secondary heart field cardioblast proliferation
0.57	GO:0071599	otic vesicle development
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0007501	mesodermal cell fate specification
0.56	GO:0010468	regulation of gene expression
0.56	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0046872	metal ion binding
0.43	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.52	GO:0016604	nuclear body
0.48	GO:0032993	protein-DNA complex
0.43	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm

0.75

GO:0004725

sp|Q99504|EYA3_HUMAN
Eyes absent homolog 3
Search

EYA3

0.75	Eyes absent homolog

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.69	GO:0007275	multicellular organism development
0.60	GO:0016576	histone dephosphorylation
0.58	GO:0045739	positive regulation of DNA repair
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0010212	response to ionizing radiation
0.52	GO:0006302	double-strand break repair
0.48	GO:1901099	negative regulation of signal transduction in absence of ligand

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0046872	metal ion binding
0.37	GO:0004992	platelet activating factor receptor activity
0.37	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.37	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.75	GO:0005667	transcription factor complex
0.53	GO:0005813	centrosome
0.49	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.75

GO:0004725

sp|Q99518|FMO2_HUMAN
Dimethylaniline monooxygenase [N-oxide-forming] 2
Search

FMO2

0.60	Flavin-containing monooxygenase

0.67	GO:0070995	NADPH oxidation
0.59	GO:0072592	oxygen metabolic process
0.53	GO:0009404	toxin metabolic process
0.52	GO:0006805	xenobiotic metabolic process
0.45	GO:0006082	organic acid metabolic process
0.40	GO:0042737	drug catabolic process
0.38	GO:0032496	response to lipopolysaccharide
0.37	GO:0006970	response to osmotic stress
0.34	GO:0043066	negative regulation of apoptotic process

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.70	GO:0050661	NADP binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0004462	lactoylglutathione lyase activity
0.33	GO:0005515	protein binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.78	EC:1.14.13.8	GO:0004499
0.34	KEGG:R02530	GO:0004462

sp|Q99519|NEUR1_HUMAN
Sialidase-1
Search

NEU1

0.82	Neuraminidase 1 (lysosomal sialidase)

0.59	GO:0009313	oligosaccharide catabolic process
0.53	GO:0006689	ganglioside catabolic process
0.37	GO:0043312	neutrophil degranulation
0.36	GO:2000291	regulation of myoblast proliferation
0.35	GO:0010976	positive regulation of neuron projection development
0.34	GO:0006397	mRNA processing

0.74	GO:0004308	exo-alpha-sialidase activity
0.36	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004386	helicase activity

0.59	GO:0005764	lysosome
0.53	GO:0030054	cell junction
0.44	GO:0005775	vacuolar lumen
0.42	GO:0098852	lytic vacuole membrane
0.40	GO:0031410	cytoplasmic vesicle
0.37	GO:0070062	extracellular exosome
0.36	GO:0031983	vesicle lumen
0.36	GO:0005886	plasma membrane
0.35	GO:0009986	cell surface
0.34	GO:0012505	endomembrane system

0.74

EC:3.2.1.18

GO:0004308

sp|Q99523|SORT_HUMAN
Sortilin
Search

SORT1

0.78

Sortilin

0.58	GO:0051005	negative regulation of lipoprotein lipase activity
0.58	GO:0038180	nerve growth factor signaling pathway
0.58	GO:0048227	plasma membrane to endosome transport
0.57	GO:0048011	neurotrophin TRK receptor signaling pathway
0.56	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.56	GO:0045599	negative regulation of fat cell differentiation
0.56	GO:0046323	glucose import
0.56	GO:0008333	endosome to lysosome transport
0.55	GO:0006895	Golgi to endosome transport
0.55	GO:0014902	myotube differentiation

0.60	GO:0030379	neurotensin receptor activity, non-G-protein coupled
0.59	GO:0010465	nerve growth factor receptor activity
0.58	GO:0048406	nerve growth factor binding
0.49	GO:0019899	enzyme binding
0.36	GO:0016492	G-protein coupled neurotensin receptor activity
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0004175	endopeptidase activity

0.69	GO:0005794	Golgi apparatus
0.54	GO:0030140	trans-Golgi network transport vesicle
0.53	GO:0005905	clathrin-coated pit
0.53	GO:0005769	early endosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0030659	cytoplasmic vesicle membrane
0.51	GO:0009986	cell surface
0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.39	GO:0005765	lysosomal membrane

sp|Q99525|H4G_HUMAN
Histone H4-like protein type G
Search

0.45	Histone-fold-containing

0.72	GO:0006334	nucleosome assembly
0.50	GO:0006352	DNA-templated transcription, initiation
0.33	GO:0006030	chitin metabolic process

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.41	GO:0042393	histone binding
0.33	GO:0008061	chitin binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.32	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q99527|GPER1_HUMAN
G-protein coupled estrogen receptor 1
Search

GPER1

0.97	G protein-coupled estrogen receptor

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:0071392	cellular response to estradiol stimulus
0.62	GO:2000724	positive regulation of cardiac vascular smooth muscle cell differentiation
0.62	GO:0070474	positive regulation of uterine smooth muscle contraction
0.61	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.60	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.59	GO:0030819	positive regulation of cAMP biosynthetic process
0.59	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.59	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.59	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol

0.70	GO:0004930	G-protein coupled receptor activity
0.63	GO:0030284	estrogen receptor activity
0.61	GO:1990239	steroid hormone binding
0.53	GO:0003682	chromatin binding
0.44	GO:0017082	mineralocorticoid receptor activity
0.34	GO:0001653	peptide receptor activity
0.34	GO:0005515	protein binding
0.33	GO:0008144	drug binding

0.57	GO:0055037	recycling endosome
0.56	GO:0045095	keratin filament
0.55	GO:0005769	early endosome
0.55	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0005802	trans-Golgi network
0.53	GO:0030659	cytoplasmic vesicle membrane
0.53	GO:0005635	nuclear envelope
0.50	GO:0005783	endoplasmic reticulum
0.44	GO:0005886	plasma membrane
0.43	GO:0044327	dendritic spine head

sp|Q99536|VAT1_HUMAN
Synaptic vesicle membrane protein VAT-1 homolog
Search

VAT1

0.93	Synaptic vesicle membrane protein VAT-1

0.62	GO:0010637	negative regulation of mitochondrial fusion
0.51	GO:0055114	oxidation-reduction process
0.36	GO:0043312	neutrophil degranulation
0.32	GO:2001141	regulation of RNA biosynthetic process

0.58	GO:0008270	zinc ion binding
0.52	GO:0016491	oxidoreductase activity
0.34	GO:0003712	transcription cofactor activity
0.34	GO:0008134	transcription factor binding
0.33	GO:0003723	RNA binding
0.32	GO:0048037	cofactor binding

0.41	GO:0005741	mitochondrial outer membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0035578	azurophil granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016491

sp|Q99538|LGMN_HUMAN
Legumain
Search

LGMN

0.93

Legumain

0.61	GO:0006508	proteolysis
0.58	GO:1901185	negative regulation of ERBB signaling pathway
0.57	GO:0040015	negative regulation of multicellular organism growth
0.57	GO:0003014	renal system process
0.56	GO:0010447	response to acidic pH
0.55	GO:0043524	negative regulation of neuron apoptotic process
0.54	GO:0032801	receptor catabolic process
0.51	GO:0044257	cellular protein catabolic process
0.46	GO:0031103	axon regeneration
0.44	GO:0042246	tissue regeneration

0.61

GO:0008233

peptidase activity

0.53	GO:0005764	lysosome
0.53	GO:0005770	late endosome
0.53	GO:0045177	apical part of cell
0.36	GO:0070062	extracellular exosome
0.36	GO:0031904	endosome lumen
0.35	GO:0005775	vacuolar lumen

0.61

GO:0008233

sp|Q99541|PLIN2_HUMAN
Perilipin-2
Search

PLIN2

0.91

Perilipin

0.73	GO:0019915	lipid storage
0.72	GO:0015909	long-chain fatty acid transport
0.47	GO:0014070	response to organic cyclic compound
0.45	GO:0042493	response to drug
0.39	GO:0019216	regulation of lipid metabolic process

0.36

GO:0005515

protein binding

0.79	GO:0005811	lipid droplet
0.61	GO:0005829	cytosol
0.55	GO:0005634	nucleus
0.51	GO:0005886	plasma membrane
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0005576	extracellular region

sp|Q99542|MMP19_HUMAN
Matrix metalloproteinase-19
Search

MMP19

0.97	Matrix metalloproteinase-19

0.59	GO:0006508	proteolysis
0.44	GO:0001554	luteolysis
0.43	GO:0001542	ovulation from ovarian follicle
0.42	GO:0006954	inflammatory response
0.42	GO:0051591	response to cAMP
0.42	GO:0001541	ovarian follicle development
0.41	GO:0060022	hard palate development
0.40	GO:0030574	collagen catabolic process
0.40	GO:0009725	response to hormone
0.38	GO:0001525	angiogenesis

0.69	GO:0004222	metalloendopeptidase activity
0.62	GO:0008270	zinc ion binding
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004601	peroxidase activity
0.33	GO:0016504	peptidase activator activity

0.73	GO:0031012	extracellular matrix
0.54	GO:0005615	extracellular space
0.36	GO:0031225	anchored component of membrane
0.35	GO:0005886	plasma membrane
0.33	GO:0035579	specific granule membrane
0.32	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.69	EC:3.4.24	GO:0004222
0.34	KEGG:R03532	GO:0004601

sp|Q99543|DNJC2_HUMAN
DnaJ homolog subfamily C member 2
Search

DNAJC2

0.93	DnaJ like protein subfamily C member 2

0.57	GO:2000279	negative regulation of DNA biosynthetic process
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0006260	DNA replication
0.40	GO:0016569	covalent chromatin modification
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:1900034	regulation of cellular response to heat
0.36	GO:0051083	'de novo' cotranslational protein folding
0.35	GO:0030308	negative regulation of cell growth
0.35	GO:0032781	positive regulation of ATPase activity

0.62	GO:0061649	ubiquitin modification-dependent histone binding
0.58	GO:0030544	Hsp70 protein binding
0.54	GO:0003682	chromatin binding
0.53	GO:0003677	DNA binding
0.35	GO:0001671	ATPase activator activity
0.34	GO:0003723	RNA binding

0.58	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.48	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.45	GO:0031090	organelle membrane
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q99547|MPH6_HUMAN
M-phase phosphoprotein 6
Search

MPHOSPH6

0.95	M-phase phosphoprotein 6

0.80

GO:0000460

maturation of 5.8S rRNA

0.37	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.79	GO:0000178	exosome (RNase complex)
0.68	GO:0031981	nuclear lumen
0.55	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0005737	cytoplasm

sp|Q99549|MPP8_HUMAN
M-phase phosphoprotein 8
Search

MPHOSPH8

0.94	M-phase phosphoprotein 8

0.58	GO:0044030	regulation of DNA methylation
0.50	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0016567	protein ubiquitination
0.37	GO:0006471	protein ADP-ribosylation
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0006396	RNA processing

0.56	GO:0140034	methylation-dependent protein binding
0.54	GO:0042393	histone binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.33	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.55	GO:0000792	heterochromatin
0.52	GO:0000786	nucleosome
0.49	GO:0005829	cytosol
0.48	GO:0031974	membrane-enclosed lumen
0.46	GO:0000151	ubiquitin ligase complex
0.42	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.37	EC:2.4.2.30	GO:0003950
0.45	KEGG:R03876	GO:0004842

sp|Q99550|MPP9_HUMAN
M-phase phosphoprotein 9
Search

MPHOSPH9

0.97	M-phase phosphoprotein 9

0.83	GO:0005814	centriole
0.72	GO:0005794	Golgi apparatus
0.42	GO:0098588	bounding membrane of organelle
0.41	GO:0031984	organelle subcompartment

sp|Q99551|MTEF1_HUMAN
Transcription termination factor 1, mitochondrial
Search

MTERF1

0.95	Mitochondrial transcription termination factor

0.71	GO:0006393	termination of mitochondrial transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0032392	DNA geometric change
0.37	GO:0006391	transcription initiation from mitochondrial promoter
0.36	GO:0007005	mitochondrion organization

0.72	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding
0.35	GO:0003723	RNA binding
0.34	GO:0043565	sequence-specific DNA binding

0.61	GO:0042645	mitochondrial nucleoid
0.53	GO:0005829	cytosol

sp|Q99558|M3K14_HUMAN
Mitogen-activated protein kinase kinase kinase 14
Search

MAP3K14

0.97	Mitogen-activated protein kinase kinase kinase 14

0.66	GO:0071260	cellular response to mechanical stimulus
0.65	GO:0038061	NIK/NF-kappaB signaling
0.65	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.64	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.62	GO:0006468	protein phosphorylation
0.60	GO:0051607	defense response to virus
0.57	GO:0006955	immune response
0.51	GO:0031098	stress-activated protein kinase signaling cascade
0.49	GO:0032147	activation of protein kinase activity
0.48	GO:0007346	regulation of mitotic cell cycle

0.69	GO:0004704	NF-kappaB-inducing kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004709	MAP kinase kinase kinase activity
0.36	GO:0005515	protein binding

0.64	GO:0001650	fibrillar center
0.54	GO:0005829	cytosol

0.69

GO:0004704

sp|Q99567|NUP88_HUMAN
Nuclear pore complex protein Nup88
Search

NUP88

0.87	Nucleoporin 88

0.85	GO:0000056	ribosomal small subunit export from nucleus
0.84	GO:0000055	ribosomal large subunit export from nucleus
0.72	GO:0006913	nucleocytoplasmic transport
0.49	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.49	GO:0034504	protein localization to nucleus
0.48	GO:0051028	mRNA transport
0.47	GO:0017038	protein import
0.47	GO:0072594	establishment of protein localization to organelle
0.39	GO:0010467	gene expression
0.34	GO:0055085	transmembrane transport

0.80	GO:0017056	structural constituent of nuclear pore
0.41	GO:0005215	transporter activity

0.62	GO:0005643	nuclear pore
0.56	GO:0005654	nucleoplasm
0.37	GO:0046930	pore complex

sp|Q99569|PKP4_HUMAN
Plakophilin-4
Search

PKP4

0.94	Plakophilin-4

0.85	GO:0032467	positive regulation of cytokinesis
0.77	GO:0098609	cell-cell adhesion
0.76	GO:0043547	positive regulation of GTPase activity
0.56	GO:0007043	cell-cell junction assembly
0.36	GO:0070268	cornification
0.34	GO:0030155	regulation of cell adhesion
0.34	GO:0007267	cell-cell signaling

0.33

GO:0005515

protein binding

0.57	GO:0030057	desmosome
0.56	GO:0044291	cell-cell contact zone
0.56	GO:0051233	spindle midzone
0.55	GO:0030496	midbody
0.55	GO:0014069	postsynaptic density
0.54	GO:0072686	mitotic spindle
0.54	GO:0000922	spindle pole
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0009898	cytoplasmic side of plasma membrane
0.35	GO:0001533	cornified envelope

sp|Q99570|PI3R4_HUMAN
Phosphoinositide 3-kinase regulatory subunit 4
Search

PIK3R4

0.91	Phosphoinositide 3-kinase regulatory subunit 4

0.62	GO:0006468	protein phosphorylation
0.60	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.57	GO:0042149	cellular response to glucose starvation
0.56	GO:0032801	receptor catabolic process
0.55	GO:0032465	regulation of cytokinesis
0.49	GO:0030242	autophagy of peroxisome
0.48	GO:0006623	protein targeting to vacuole
0.48	GO:0045324	late endosome to vacuole transport
0.47	GO:0016236	macroautophagy
0.36	GO:0034162	toll-like receptor 9 signaling pathway

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005515	protein binding

0.58	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.58	GO:0005770	late endosome
0.55	GO:0005930	axoneme
0.51	GO:0015630	microtubule cytoskeleton
0.50	GO:0071561	nucleus-vacuole junction
0.46	GO:0005643	nuclear pore
0.41	GO:0005776	autophagosome
0.36	GO:0030670	phagocytic vesicle membrane
0.34	GO:0005829	cytosol

0.36	EC:2.7.1.137	GO:0016303
0.36	KEGG:R03362	GO:0016303

sp|Q99571|P2RX4_HUMAN
P2X purinoceptor 4
Search

P2RX4

0.92	Purinergic receptor P2X 4

0.85	GO:0033198	response to ATP
0.84	GO:0035590	purinergic nucleotide receptor signaling pathway
0.79	GO:0060079	excitatory postsynaptic potential
0.61	GO:0098655	cation transmembrane transport
0.58	GO:0055119	relaxation of cardiac muscle
0.57	GO:2001028	positive regulation of endothelial cell chemotaxis
0.57	GO:0010614	negative regulation of cardiac muscle hypertrophy
0.56	GO:0034405	response to fluid shear stress
0.56	GO:0010524	positive regulation of calcium ion transport into cytosol
0.56	GO:0051899	membrane depolarization

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.84	GO:0001614	purinergic nucleotide receptor activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0099604	ligand-gated calcium channel activity
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.53	GO:0045296	cadherin binding
0.37	GO:0042802	identical protein binding
0.37	GO:0005102	receptor binding

0.77	GO:0098794	postsynapse
0.66	GO:0005887	integral component of plasma membrane
0.52	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0030054	cell junction
0.48	GO:0005639	integral component of nuclear inner membrane
0.39	GO:0043195	terminal bouton
0.39	GO:0044309	neuron spine
0.39	GO:0043025	neuronal cell body
0.38	GO:0009897	external side of plasma membrane
0.38	GO:0032279	asymmetric synapse

sp|Q99572|P2RX7_HUMAN
P2X purinoceptor 7
Search

sp|Q99574|NEUS_HUMAN
Neuroserpin
Search

SERPINI1

0.96	Putative neuroserpin is a inhibitory member of the serine proteinase inhibitor

0.58	GO:0010951	negative regulation of endopeptidase activity
0.52	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.39	GO:0010976	positive regulation of neuron projection development
0.38	GO:0030155	regulation of cell adhesion
0.36	GO:0002438	acute inflammatory response to antigenic stimulus
0.36	GO:0007595	lactation
0.35	GO:0007584	response to nutrient
0.35	GO:0007596	blood coagulation
0.35	GO:0071391	cellular response to estrogen stimulus
0.35	GO:0007422	peripheral nervous system development

0.60	GO:0004867	serine-type endopeptidase inhibitor activity
0.49	GO:0008201	heparin binding
0.43	GO:0002020	protease binding
0.40	GO:0042802	identical protein binding
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0008233	peptidase activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.32	GO:0046872	metal ion binding
0.32	GO:0016874	ligase activity
0.32	GO:0016740	transferase activity

0.73	GO:0005615	extracellular space
0.58	GO:0060205	cytoplasmic vesicle lumen
0.55	GO:0043025	neuronal cell body
0.54	GO:0030141	secretory granule
0.37	GO:1903561	extracellular vesicle
0.33	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.33	GO:0005788	endoplasmic reticulum lumen
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0008233

sp|Q99575|POP1_HUMAN
Ribonucleases P/MRP protein subunit POP1
Search

POP1

0.93	Processing of 1, ribonuclease P/MRP subunit

0.78	GO:0001682	tRNA 5'-leader removal
0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.61	GO:0016078	tRNA catabolic process
0.37	GO:0000132	establishment of mitotic spindle orientation
0.35	GO:0051301	cell division
0.32	GO:0006364	rRNA processing
0.32	GO:0006508	proteolysis
0.31	GO:0006518	peptide metabolic process
0.31	GO:0043604	amide biosynthetic process
0.31	GO:0044267	cellular protein metabolic process

0.78	GO:0004526	ribonuclease P activity
0.64	GO:0000171	ribonuclease MRP activity
0.37	GO:0070840	dynein complex binding
0.36	GO:0003723	RNA binding
0.32	GO:0004252	serine-type endopeptidase activity
0.32	GO:0003735	structural constituent of ribosome

0.61	GO:0005655	nucleolar ribonuclease P complex
0.60	GO:0000172	ribonuclease MRP complex
0.38	GO:0005615	extracellular space
0.36	GO:0005875	microtubule associated complex
0.36	GO:0005815	microtubule organizing center
0.36	GO:0005874	microtubule
0.35	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.1.26.5

GO:0004526

sp|Q99576|T22D3_HUMAN
TSC22 domain family protein 3
Search

TSC22D3

0.39	Glucocorticoid-induced leucine zipper protein

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0070236	negative regulation of activation-induced cell death of T cells
0.48	GO:0048642	negative regulation of skeletal muscle tissue development
0.45	GO:0006970	response to osmotic stress
0.43	GO:0051253	negative regulation of RNA metabolic process
0.43	GO:0010558	negative regulation of macromolecule biosynthetic process
0.42	GO:0031327	negative regulation of cellular biosynthetic process
0.40	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0043426	MRF binding
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|Q99578|RIT2_HUMAN
GTP-binding protein Rit2
Search

RIT2

0.96	Ras like without CAAX 2

0.61	GO:0007165	signal transduction
0.55	GO:0032489	regulation of Cdc42 protein signal transduction
0.52	GO:0010976	positive regulation of neuron projection development
0.52	GO:0010977	negative regulation of neuron projection development
0.52	GO:0030100	regulation of endocytosis
0.51	GO:0032507	maintenance of protein location in cell
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0006970	response to osmotic stress
0.41	GO:0042594	response to starvation
0.40	GO:0009408	response to heat

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.55	GO:0030215	semaphorin receptor binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005516	calmodulin binding
0.49	GO:0003682	chromatin binding
0.36	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding

0.51	GO:0045121	membrane raft
0.50	GO:0097447	dendritic tree
0.50	GO:0044297	cell body
0.45	GO:0005886	plasma membrane
0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|Q99581|FEV_HUMAN
Protein FEV
Search

FEV

0.96	FEV, ETS transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048665	neuron fate specification
0.55	GO:0042551	neuron maturation
0.52	GO:0010604	positive regulation of macromolecule metabolic process
0.50	GO:2000504	positive regulation of blood vessel remodeling
0.50	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation
0.48	GO:0003197	endocardial cushion development
0.45	GO:0016477	cell migration

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003682	chromatin binding
0.45	GO:0003690	double-stranded DNA binding
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0035326	enhancer binding
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005515	protein binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0043025	neuronal cell body
0.33	GO:0019773	proteasome core complex, alpha-subunit complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016773

sp|Q99583|MNT_HUMAN
Max-binding protein MNT
Search

MNT

0.97	MAX network transcriptional repressor b

0.63	GO:2001234	negative regulation of apoptotic signaling pathway
0.63	GO:0007569	cell aging
0.60	GO:0000122	negative regulation of transcription by RNA polymerase II
0.57	GO:0051726	regulation of cell cycle

0.68	GO:0046983	protein dimerization activity
0.63	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.60	GO:0003682	chromatin binding

0.55

GO:0005654

nucleoplasm

sp|Q99584|S10AD_HUMAN
Protein S100-A13
Search

S100A13

0.97	S100 calcium binding protein A13

0.71	GO:0050703	interleukin-1 alpha secretion
0.63	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.51	GO:0090026	positive regulation of monocyte chemotaxis
0.51	GO:0071624	positive regulation of granulocyte chemotaxis
0.50	GO:0034142	toll-like receptor 4 signaling pathway
0.49	GO:0032496	response to lipopolysaccharide
0.47	GO:0042742	defense response to bacterium
0.40	GO:0002279	mast cell activation involved in immune response
0.40	GO:0002448	mast cell mediated immunity
0.40	GO:0051602	response to electrical stimulus

0.70	GO:0005509	calcium ion binding
0.67	GO:0050786	RAGE receptor binding
0.67	GO:0005507	copper ion binding
0.66	GO:0017134	fibroblast growth factor binding
0.58	GO:0042803	protein homodimerization activity
0.50	GO:0008270	zinc ion binding
0.49	GO:0042379	chemokine receptor binding
0.39	GO:0008289	lipid binding
0.33	GO:0008144	drug binding

0.65	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0005829	cytosol
0.57	GO:0031981	nuclear lumen
0.57	GO:0005615	extracellular space
0.48	GO:0005886	plasma membrane
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0030054	cell junction
0.40	GO:0042629	mast cell granule
0.39	GO:1903561	extracellular vesicle

sp|Q99590|SCAFB_HUMAN
Protein SCAF11
Search

SCAF11

0.96	SR-related CTD-associated factor 11

0.82	GO:0000245	spliceosomal complex assembly
0.38	GO:0016558	protein import into peroxisome matrix

0.32

GO:0046872

metal ion binding

0.78	GO:0016604	nuclear body
0.73	GO:0005730	nucleolus
0.38	GO:0031903	microbody membrane
0.38	GO:0044439	peroxisomal part

sp|Q99592|ZBT18_HUMAN
Zinc finger and BTB domain-containing protein 18
Search

ZBTB18

0.97	Zinc finger and BTB domain-containing protein 18

0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0007517	muscle organ development
0.39	GO:0014706	striated muscle tissue development
0.39	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0021766	hippocampus development
0.37	GO:0021549	cerebellum development
0.37	GO:0021987	cerebral cortex development
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0001701	in utero embryonic development
0.36	GO:0048872	homeostasis of number of cells

0.54	GO:0003713	transcription coactivator activity
0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.46	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005694	chromosome
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm

sp|Q99593|TBX5_HUMAN
T-box transcription factor TBX5
Search

TBX5

0.97	Regeneration blastema forelimb-specific Tbx

0.62	GO:0035108	limb morphogenesis
0.62	GO:0035113	embryonic appendage morphogenesis
0.61	GO:0060039	pericardium development
0.61	GO:0051891	positive regulation of cardioblast differentiation
0.60	GO:0060044	negative regulation of cardiac muscle cell proliferation
0.59	GO:0003218	cardiac left ventricle formation
0.59	GO:0003181	atrioventricular valve morphogenesis
0.59	GO:0003166	bundle of His development
0.58	GO:0072513	positive regulation of secondary heart field cardioblast proliferation
0.58	GO:0030324	lung development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0008134	transcription factor binding
0.38	GO:0030274	LIM domain binding
0.37	GO:0097110	scaffold protein binding
0.36	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.51	GO:0032993	protein-DNA complex
0.41	GO:0015629	actin cytoskeleton
0.39	GO:0005737	cytoplasm
0.36	GO:0099513	polymeric cytoskeletal fiber
0.34	GO:0005667	transcription factor complex
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

sp|Q99594|TEAD3_HUMAN
Transcriptional enhancer factor TEF-5
Search

TEAD3

0.97	Transcriptional enhancer factor TEF-5

0.82	GO:0035329	hippo signaling
0.66	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0006351	transcription, DNA-templated
0.47	GO:0048568	embryonic organ development
0.39	GO:0055059	asymmetric neuroblast division
0.38	GO:1902459	positive regulation of stem cell population maintenance
0.35	GO:0007565	female pregnancy
0.34	GO:0007517	muscle organ development
0.34	GO:0001501	skeletal system development

0.60	GO:0003700	DNA binding transcription factor activity
0.52	GO:0003677	DNA binding
0.48	GO:0001085	RNA polymerase II transcription factor binding
0.46	GO:0001067	regulatory region nucleic acid binding

0.55	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

sp|Q99595|TI17A_HUMAN
Mitochondrial import inner membrane translocase subunit Tim17-A
Search

TIMM17A

0.87	Mitochondrial import inner membrane translocase subunit Tim17-A

0.63	GO:0071806	protein transmembrane transport
0.62	GO:0006886	intracellular protein transport
0.45	GO:1990542	mitochondrial transmembrane transport
0.45	GO:0072655	establishment of protein localization to mitochondrion
0.44	GO:0007005	mitochondrion organization
0.44	GO:0017038	protein import
0.39	GO:0010954	positive regulation of protein processing
0.33	GO:0008643	carbohydrate transport
0.33	GO:1902600	hydrogen ion transmembrane transport

0.67	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.34	GO:0005351	sugar:proton symporter activity
0.34	GO:0005515	protein binding

0.73	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.55	GO:0031305	integral component of mitochondrial inner membrane
0.46	GO:0005654	nucleoplasm
0.33	GO:0000139	Golgi membrane

sp|Q99598|TSNAX_HUMAN
Translin-associated protein X
Search

TSNAX

0.90	Translin-associated protein X

0.40	GO:0007283	spermatogenesis
0.38	GO:0030154	cell differentiation
0.38	GO:0007275	multicellular organism development
0.35	GO:0030422	production of siRNA involved in RNA interference
0.33	GO:0015031	protein transport

0.65	GO:0043565	sequence-specific DNA binding
0.38	GO:0031687	A2A adenosine receptor binding
0.36	GO:0032403	protein complex binding
0.35	GO:0003697	single-stranded DNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0008565	protein transporter activity
0.34	GO:0003723	RNA binding

0.41	GO:0005634	nucleus
0.40	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005794	Golgi apparatus
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q99603|Q99603_HUMAN
T-cell receptor gamma variable 9 (Fragment)
Search

sp|Q99607|ELF4_HUMAN
ETS-related transcription factor Elf-4
Search

ELF4

0.96	E74 like ETS transcription factor 4

0.83	GO:0001787	natural killer cell proliferation
0.83	GO:0001866	NK T cell proliferation
0.71	GO:0045087	innate immune response
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006366	transcription by RNA polymerase II
0.49	GO:0050860	negative regulation of T cell receptor signaling pathway
0.46	GO:0001817	regulation of cytokine production
0.45	GO:0030154	cell differentiation
0.34	GO:0050855	regulation of B cell receptor signaling pathway
0.33	GO:0001959	regulation of cytokine-mediated signaling pathway

0.69	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part

sp|Q99608|NECD_HUMAN
Necdin
Search

NDN

0.97	Magphinin delta

0.75	GO:0008285	negative regulation of cell proliferation
0.73	GO:0048666	neuron development
0.61	GO:0003016	respiratory system process
0.60	GO:0048011	neurotrophin TRK receptor signaling pathway
0.60	GO:0071514	genetic imprinting
0.59	GO:0008347	glial cell migration
0.59	GO:0019233	sensory perception of pain
0.58	GO:0001764	neuron migration
0.57	GO:0048588	developmental cell growth
0.57	GO:0060560	developmental growth involved in morphogenesis

0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0043015	gamma-tubulin binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.54	GO:0005829	cytosol
0.54	GO:0005813	centrosome
0.54	GO:0031981	nuclear lumen
0.49	GO:0042995	cell projection
0.37	GO:0043204	perikaryon
0.35	GO:0031093	platelet alpha granule lumen
0.33	GO:0005576	extracellular region
0.33	GO:0005887	integral component of plasma membrane

sp|Q99611|SPS2_HUMAN
Selenide, water dikinase 2
Search

SEPHS2

0.92	Selenophosphate synthetase 2

0.78	GO:0016260	selenocysteine biosynthetic process
0.57	GO:0016310	phosphorylation
0.49	GO:0001887	selenium compound metabolic process
0.32	GO:0006464	cellular protein modification process

0.82	GO:0004756	selenide, water dikinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042802	identical protein binding
0.35	GO:0046982	protein heterodimerization activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding

0.36	GO:0031965	nuclear membrane
0.35	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

0.82	EC:2.7.9.3	GO:0004756
0.82	KEGG:R03595	GO:0004756

sp|Q99612|KLF6_HUMAN
Krueppel-like factor 6
Search

KLF6

0.97	Kruppel like factor 6

0.50	GO:0006366	transcription by RNA polymerase II
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0021634	optic nerve formation
0.41	GO:0043249	erythrocyte maturation
0.40	GO:0035265	organ growth
0.40	GO:0031016	pancreas development
0.40	GO:0001889	liver development
0.39	GO:0048565	digestive tract development
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0019221	cytokine-mediated signaling pathway

0.53	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001158	enhancer sequence-specific DNA binding
0.39	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38	GO:0003682	chromatin binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.53	GO:0001650	fibrillar center
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q99613|EIF3C_HUMAN
Eukaryotic translation initiation factor 3 subunit C
Search

EIF3C

0.70	Eukaryotic translation initiation factor 3 subunit C

0.75	GO:0001731	formation of translation preinitiation complex
0.74	GO:0006446	regulation of translational initiation
0.40	GO:1902416	positive regulation of mRNA binding
0.38	GO:0045727	positive regulation of translation

0.81	GO:0031369	translation initiation factor binding
0.71	GO:0003743	translation initiation factor activity
0.34	GO:0043022	ribosome binding

0.76	GO:0005852	eukaryotic translation initiation factor 3 complex
0.74	GO:0016282	eukaryotic 43S preinitiation complex
0.74	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q99614|TTC1_HUMAN
Tetratricopeptide repeat protein 1
Search

TTC1

0.88	Tetratricopeptide repeat protein 1

0.44	GO:0055117	regulation of cardiac muscle contraction
0.44	GO:0071875	adrenergic receptor signaling pathway
0.44	GO:0019229	regulation of vasoconstriction
0.37	GO:0006457	protein folding
0.37	GO:0001522	pseudouridine synthesis
0.36	GO:0010467	gene expression
0.35	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.34	GO:0009059	macromolecule biosynthetic process

0.45	GO:0004937	alpha1-adrenergic receptor activity
0.38	GO:0005515	protein binding
0.37	GO:0009982	pseudouridine synthase activity
0.36	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding

0.66	GO:0005829	cytosol
0.42	GO:0031903	microbody membrane
0.42	GO:0044439	peroxisomal part
0.37	GO:0015934	large ribosomal subunit
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37

GO:0009982

sp|Q99615|DNJC7_HUMAN
DnaJ homolog subfamily C member 7
Search

DNAJC7

0.90	DnaJ like protein subfamily C member 7

0.81	GO:0051085	chaperone cofactor-dependent protein refolding
0.41	GO:1900034	regulation of cellular response to heat
0.40	GO:0032781	positive regulation of ATPase activity

0.76	GO:0031072	heat shock protein binding
0.40	GO:0001671	ATPase activator activity

0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.46	GO:0070062	extracellular exosome
0.42	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q99616|CCL13_HUMAN
C-C motif chemokine 13
Search

0.75	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.68	GO:0097529	myeloid leukocyte migration
0.60	GO:0071674	mononuclear cell migration
0.58	GO:0071347	cellular response to interleukin-1
0.58	GO:0006954	inflammatory response
0.57	GO:0071356	cellular response to tumor necrosis factor
0.56	GO:0019221	cytokine-mediated signaling pathway
0.56	GO:0072676	lymphocyte migration

0.84	GO:0008009	chemokine activity
0.62	GO:0048020	CCR chemokine receptor binding
0.49	GO:0016004	phospholipase activator activity
0.44	GO:0046983	protein dimerization activity
0.41	GO:0004672	protein kinase activity
0.40	GO:0005153	interleukin-8 receptor binding
0.40	GO:0031737	CX3C chemokine receptor binding
0.38	GO:0005178	integrin binding
0.35	GO:0008201	heparin binding

0.70	GO:0005615	extracellular space
0.37	GO:0009986	cell surface
0.36	GO:0005622	intracellular
0.33	GO:0098794	postsynapse
0.32	GO:0042995	cell projection
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q99618|CDCA3_HUMAN
Cell division cycle-associated protein 3
Search

CDCA3

0.97	Cell division cycle-associated protein 3

0.59	GO:0051301	cell division
0.42	GO:0016567	protein ubiquitination
0.40	GO:0007049	cell cycle

0.36

GO:0005515

protein binding

0.72	GO:0005913	cell-cell adherens junction
0.41	GO:0005829	cytosol

sp|Q99619|SPSB2_HUMAN
SPRY domain-containing SOCS box protein 2
Search

0.89	SPRY domain-containing SOCS box protein 2

0.61	GO:0035556	intracellular signal transduction
0.55	GO:0016567	protein ubiquitination
0.38	GO:0043687	post-translational protein modification

0.37

GO:0005515

protein binding

0.44

GO:0005622

intracellular

sp|Q99622|C10_HUMAN
Protein C10
Search

0.97	Gene-rich cluster, C10 gene

0.85	GO:0036343	psychomotor behavior
0.85	GO:0021678	third ventricle development
0.85	GO:0021540	corpus callosum morphogenesis
0.85	GO:0014819	regulation of skeletal muscle contraction
0.79	GO:0048593	camera-type eye morphogenesis
0.77	GO:0050890	cognition
0.74	GO:0009791	post-embryonic development

0.76	GO:0016607	nuclear speck
0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q99623|PHB2_HUMAN
Prohibitin-2
Search

PHB2

0.85	Prohibitin 2

0.56	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.56	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis
0.55	GO:0031536	positive regulation of exit from mitosis
0.55	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.54	GO:0000060	protein import into nucleus, translocation
0.54	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.53	GO:0060744	mammary gland branching involved in thelarche
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.53	GO:0043433	negative regulation of DNA binding transcription factor activity
0.52	GO:0051091	positive regulation of DNA binding transcription factor activity

0.53	GO:0047485	protein N-terminus binding
0.52	GO:0008022	protein C-terminus binding
0.47	GO:0033218	amide binding
0.35	GO:0030331	estrogen receptor binding

0.54	GO:0016363	nuclear matrix
0.50	GO:0005741	mitochondrial outer membrane
0.49	GO:0009986	cell surface
0.44	GO:0005743	mitochondrial inner membrane
0.43	GO:0043234	protein complex
0.41	GO:0071944	cell periphery
0.38	GO:0030424	axon
0.36	GO:0070062	extracellular exosome
0.35	GO:0070382	exocytic vesicle

sp|Q99624|S38A3_HUMAN
Sodium-coupled neutral amino acid transporter 3
Search

SLC38A3

0.96	Sodium-coupled neutral amino acid transporter 3

0.61	GO:0006867	asparagine transport
0.59	GO:0006868	glutamine transport
0.59	GO:0015817	histidine transport
0.59	GO:0089709	L-histidine transmembrane transport
0.58	GO:0015808	L-alanine transport
0.58	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
0.58	GO:0051365	cellular response to potassium ion starvation
0.41	GO:2000487	positive regulation of glutamine transport
0.41	GO:0015816	glycine transport
0.39	GO:0007565	female pregnancy

0.61	GO:0015182	L-asparagine transmembrane transporter activity
0.60	GO:0015186	L-glutamine transmembrane transporter activity
0.59	GO:0005290	L-histidine transmembrane transporter activity
0.58	GO:0015180	L-alanine transmembrane transporter activity
0.41	GO:0015187	glycine transmembrane transporter activity
0.37	GO:0015293	symporter activity
0.37	GO:0015297	antiporter activity

0.49	GO:0005887	integral component of plasma membrane
0.38	GO:0016323	basolateral plasma membrane

sp|Q99626|CDX2_HUMAN
Homeobox protein CDX-2
Search

CDX2

0.85	Homeodomain transcription factor

0.66	GO:0007275	multicellular organism development
0.65	GO:0014807	regulation of somitogenesis
0.61	GO:0035019	somatic stem cell population maintenance
0.61	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.61	GO:0008333	endosome to lysosome transport
0.59	GO:0002065	columnar/cuboidal epithelial cell differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0045597	positive regulation of cell differentiation
0.56	GO:0010468	regulation of gene expression

0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0035326	enhancer binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.59	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0003714	transcription corepressor activity
0.56	GO:0003690	double-stranded DNA binding
0.41	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0005328	neurotransmitter:sodium symporter activity

0.61	GO:0005634	nucleus
0.58	GO:0017053	transcriptional repressor complex
0.55	GO:0000793	condensed chromosome
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0043234	protein complex
0.45	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.10.1

GO:0004714

sp|Q99627|CSN8_HUMAN
COP9 signalosome complex subunit 8
Search

COPS8

0.94	COP9 constitutive photomorphogenic homolog subunit 8

0.86	GO:0010387	COP9 signalosome assembly
0.83	GO:0000338	protein deneddylation
0.56	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.52	GO:0008285	negative regulation of cell proliferation
0.35	GO:0043687	post-translational protein modification
0.35	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.35	GO:0006283	transcription-coupled nucleotide-excision repair
0.33	GO:0006413	translational initiation
0.32	GO:0006396	RNA processing

0.33	GO:0003743	translation initiation factor activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding
0.32	GO:0016874	ligase activity

0.80	GO:0008180	COP9 signalosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

GO:0016874

sp|Q99633|PRP18_HUMAN
Pre-mRNA-splicing factor 18
Search

PRPF18

0.85	Pre-mRNA-splicing factor 18

0.72	GO:0008380	RNA splicing
0.48	GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription
0.42	GO:0006397	mRNA processing
0.42	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0032269	negative regulation of cellular protein metabolic process

0.47

GO:0000386

second spliceosomal transesterification activity

0.74	GO:0005681	spliceosomal complex
0.45	GO:0005682	U5 snRNP
0.44	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.43	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

sp|Q99638|RAD9A_HUMAN
Cell cycle checkpoint control protein RAD9A
Search

RAD9A

0.92	G protein-coupled receptor kinase 2

0.81	GO:0000077	DNA damage checkpoint
0.61	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.61	GO:0006281	DNA repair
0.60	GO:0071479	cellular response to ionizing radiation
0.59	GO:0044774	mitotic DNA integrity checkpoint
0.50	GO:0000076	DNA replication checkpoint
0.49	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:1901796	regulation of signal transduction by p53 class mediator
0.34	GO:0006260	DNA replication
0.33	GO:0006310	DNA recombination

0.58	GO:0042826	histone deacetylase binding
0.55	GO:0017124	SH3 domain binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0008408	3'-5' exonuclease activity
0.39	GO:0008853	exodeoxyribonuclease III activity

0.84	GO:0030896	checkpoint clamp complex
0.50	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

EC:3.1.11.2

GO:0008853

sp|Q99640|PMYT1_HUMAN
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Search

PKMYT1

0.97	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

0.63	GO:0006468	protein phosphorylation
0.55	GO:0010923	negative regulation of phosphatase activity
0.40	GO:0007049	cell cycle
0.36	GO:0071900	regulation of protein serine/threonine kinase activity
0.36	GO:1904029	regulation of cyclin-dependent protein kinase activity
0.36	GO:0007346	regulation of mitotic cell cycle
0.35	GO:0010564	regulation of cell cycle process
0.35	GO:0051783	regulation of nuclear division
0.33	GO:0007231	osmosensory signaling pathway
0.33	GO:0006972	hyperosmotic response

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.33	GO:0035591	signaling adaptor activity
0.33	GO:0004596	peptide alpha-N-acetyltransferase activity
0.32	GO:0004871	signal transducer activity
0.32	GO:0005198	structural molecule activity

0.50	GO:0005730	nucleolus
0.50	GO:0005794	Golgi apparatus
0.37	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.33	GO:0031416	NatB complex
0.33	GO:0005934	cellular bud tip
0.33	GO:0005935	cellular bud neck
0.33	GO:1990315	Mcs4 RR-MAPKKK complex

0.33

EC:2.3.1.88

GO:0004596

sp|Q99643|C560_HUMAN
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
Search

SDHC

0.95	Chain C, Avian Respiratory Complex Ii With Oxaloacetate And Ubiquinone

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.42	GO:0006119	oxidative phosphorylation
0.38	GO:0008340	determination of adult lifespan
0.36	GO:0006979	response to oxidative stress

0.76	GO:0000104	succinate dehydrogenase activity
0.61	GO:0009055	electron transfer activity
0.52	GO:0046872	metal ion binding
0.37	GO:0020037	heme binding
0.36	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
0.33	GO:0005515	protein binding
0.32	GO:0048038	quinone binding
0.32	GO:0051287	NAD binding
0.32	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.78	GO:0045281	succinate dehydrogenase complex
0.50	GO:0045283	fumarate reductase complex
0.47	GO:0005746	mitochondrial respiratory chain
0.46	GO:0098800	inner mitochondrial membrane protein complex
0.30	GO:0016021	integral component of membrane

0.76

EC:1.3.99.1

GO:0000104

sp|Q99645|EPYC_HUMAN
Epiphycan
Search

EPYC

0.97	Dermatan sulfate proteoglycan 3

0.74	GO:0007409	axonogenesis
0.44	GO:0007565	female pregnancy
0.43	GO:0016525	negative regulation of angiogenesis
0.39	GO:0022617	extracellular matrix disassembly

0.41	GO:0005539	glycosaminoglycan binding
0.40	GO:0005201	extracellular matrix structural constituent
0.36	GO:0005515	protein binding

0.74	GO:0005578	proteinaceous extracellular matrix
0.69	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q99650|OSMR_HUMAN
Oncostatin-M-specific receptor subunit beta
Search

OSMR

0.91	Oncostatin M receptor

0.85	GO:0038165	oncostatin-M-mediated signaling pathway
0.73	GO:0008284	positive regulation of cell proliferation

0.85	GO:0004924	oncostatin-M receptor activity
0.76	GO:0019838	growth factor binding

0.85	GO:0005900	oncostatin-M receptor complex
0.75	GO:0016324	apical plasma membrane

sp|Q99653|CHP1_HUMAN
Calcineurin B homologous protein 1
Search

CHP1

0.89	Calcineurin B like proteinous protein 1

0.68	GO:0032417	positive regulation of sodium:proton antiporter activity
0.67	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade
0.63	GO:0042308	negative regulation of protein import into nucleus
0.63	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.62	GO:0051453	regulation of intracellular pH
0.61	GO:0010923	negative regulation of phosphatase activity
0.60	GO:1901214	regulation of neuron death
0.47	GO:0060050	positive regulation of protein glycosylation
0.47	GO:0031953	negative regulation of protein autophosphorylation
0.46	GO:0090314	positive regulation of protein targeting to membrane

0.70	GO:0005509	calcium ion binding
0.63	GO:0048306	calcium-dependent protein binding
0.45	GO:0004860	protein kinase inhibitor activity
0.43	GO:0019900	kinase binding
0.42	GO:0008017	microtubule binding
0.37	GO:0005215	transporter activity
0.37	GO:0015459	potassium channel regulator activity
0.36	GO:0016174	NAD(P)H oxidase activity

0.45	GO:0005886	plasma membrane
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.43	GO:0030133	transport vesicle
0.42	GO:0000139	Golgi membrane
0.41	GO:0015630	microtubule cytoskeleton
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0005634	nucleus
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol

0.36

EC:1.6.3.1

GO:0016174

sp|Q99661|KIF2C_HUMAN
Kinesin-like protein KIF2C
Search

sp|Q99665|I12R2_HUMAN
Interleukin-12 receptor subunit beta-2
Search

IL12RB2

0.97	Interleukin-12 receptor subunit beta-2

0.77	GO:0019221	cytokine-mediated signaling pathway
0.71	GO:0032609	interferon-gamma production
0.70	GO:0032729	positive regulation of interferon-gamma production
0.66	GO:0032496	response to lipopolysaccharide
0.62	GO:0018108	peptidyl-tyrosine phosphorylation
0.45	GO:0071349	cellular response to interleukin-12
0.39	GO:0045622	regulation of T-helper cell differentiation
0.39	GO:0008284	positive regulation of cell proliferation
0.34	GO:0048302	regulation of isotype switching to IgG isotypes
0.34	GO:0002829	negative regulation of type 2 immune response

0.79	GO:0004896	cytokine receptor activity
0.63	GO:0019901	protein kinase binding
0.40	GO:0019972	interleukin-12 binding

0.65	GO:0009897	external side of plasma membrane
0.41	GO:0042022	interleukin-12 receptor complex

sp|Q99666|RGPD5_HUMAN
RANBP2-like and GRIP domain-containing protein 5/6
Search

0.93	RANBP2-like and GRIP domain-containing protein 8

0.69	GO:0046907	intracellular transport
0.49	GO:0000413	protein peptidyl-prolyl isomerization
0.46	GO:0046604	positive regulation of mitotic centrosome separation
0.44	GO:0000082	G1/S transition of mitotic cell cycle
0.44	GO:0006606	protein import into nucleus
0.44	GO:0007051	spindle organization
0.42	GO:0043547	positive regulation of GTPase activity
0.42	GO:0006405	RNA export from nucleus
0.42	GO:0006511	ubiquitin-dependent protein catabolic process

0.49	GO:0008536	Ran GTPase binding
0.49	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0005096	GTPase activator activity
0.41	GO:0046872	metal ion binding

0.45	GO:0005622	intracellular
0.40	GO:0044422	organelle part
0.40	GO:0012505	endomembrane system
0.40	GO:0043227	membrane-bounded organelle
0.38	GO:0031975	envelope
0.38	GO:0043234	protein complex
0.38	GO:0043228	non-membrane-bounded organelle

0.49

EC:5.2.1.8

GO:0003755

sp|Q99674|CGRE1_HUMAN
Cell growth regulator with EF hand domain protein 1
Search

CGREF1

0.94	Cell growth regulator with EF hand domain protein 1

0.48	GO:0007050	cell cycle arrest
0.44	GO:0007155	cell adhesion
0.42	GO:0008285	negative regulation of cell proliferation
0.39	GO:0030308	negative regulation of cell growth
0.37	GO:0042338	cuticle development involved in collagen and cuticulin-based cuticle molting cycle

0.69	GO:0005509	calcium ion binding
0.37	GO:0042302	structural constituent of cuticle
0.37	GO:0005201	extracellular matrix structural constituent
0.32	GO:0003677	DNA binding

0.42	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q99675|CGRF1_HUMAN
Cell growth regulator with RING finger domain protein 1
Search

CGRRF1

0.97	Cell growth regulator with RING finger domain protein 1

0.40	GO:0007050	cell cycle arrest
0.36	GO:0030308	negative regulation of cell growth
0.36	GO:0008285	negative regulation of cell proliferation
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0006401	RNA catabolic process

0.35	GO:0046872	metal ion binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0003724	RNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016874	ligase activity

0.52	GO:0005654	nucleoplasm
0.38	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.33

GO:0004725

sp|Q99676|ZN184_HUMAN
Zinc finger protein 184
Search

0.73	Zinc finger protein 184

0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:0010468	regulation of gene expression
0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity

0.43	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part

sp|Q99677|LPAR4_HUMAN
Lysophosphatidic acid receptor 4
Search

LPAR4

0.97	Lysophosphatidic acid receptor 4

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0035025	positive regulation of Rho protein signal transduction
0.48	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.44	GO:0001525	angiogenesis

0.71	GO:0004930	G-protein coupled receptor activity
0.59	GO:0035727	lysophosphatidic acid binding

0.52	GO:0016604	nuclear body
0.45	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q99678|GPR20_HUMAN
G-protein coupled receptor 20
Search

GPR20

0.89	G-protein coupled receptor 20

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0035025	positive regulation of Rho protein signal transduction
0.51	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.42	GO:1904323	regulation of inhibitory G-protein coupled receptor phosphorylation
0.41	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.41	GO:0043951	negative regulation of cAMP-mediated signaling
0.40	GO:0007512	adult heart development
0.40	GO:1904427	positive regulation of calcium ion transmembrane transport
0.40	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.40	GO:0060976	coronary vasculature development

0.72	GO:0004930	G-protein coupled receptor activity
0.39	GO:0001653	peptide receptor activity
0.36	GO:0004896	cytokine receptor activity
0.35	GO:0001614	purinergic nucleotide receptor activity
0.33	GO:0001618	virus receptor activity
0.32	GO:0009982	pseudouridine synthase activity
0.32	GO:0015026	coreceptor activity
0.32	GO:0019960	C-X3-C chemokine binding
0.32	GO:0004931	extracellularly ATP-gated cation channel activity
0.32	GO:0042277	peptide binding

0.55	GO:0043235	receptor complex
0.50	GO:0005887	integral component of plasma membrane
0.32	GO:0005768	endosome
0.32	GO:0098794	postsynapse
0.32	GO:0005654	nucleoplasm

0.32

GO:0009982

sp|Q99679|GPR21_HUMAN
Probable G-protein coupled receptor 21
Search

0.97	G protein-coupled receptor 21

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0046627	negative regulation of insulin receptor signaling pathway
0.45	GO:0040018	positive regulation of multicellular organism growth
0.43	GO:0042593	glucose homeostasis
0.41	GO:0042493	response to drug
0.38	GO:0007626	locomotory behavior

0.70	GO:0004930	G-protein coupled receptor activity
0.44	GO:0030594	neurotransmitter receptor activity

0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q99680|GPR22_HUMAN
Probable G-protein coupled receptor 22
Search

GPR22

0.89	G protein-coupled receptor 22

0.67	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:1901652	response to peptide
0.43	GO:0032870	cellular response to hormone stimulus

0.68	GO:0004930	G-protein coupled receptor activity
0.44	GO:0042277	peptide binding

0.41

GO:0005887

integral component of plasma membrane

sp|Q99683|M3K5_HUMAN
Mitogen-activated protein kinase kinase kinase 5
Search

MAP3K5

0.97	Mitogen-activated protein kinase kinase kinase 5

0.63	GO:0006468	protein phosphorylation
0.58	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.57	GO:0000186	activation of MAPKK activity
0.57	GO:1902170	cellular response to reactive nitrogen species
0.57	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.57	GO:0045663	positive regulation of myoblast differentiation
0.56	GO:0097300	programmed necrotic cell death
0.56	GO:1901216	positive regulation of neuron death
0.56	GO:0043507	positive regulation of JUN kinase activity
0.56	GO:0034198	cellular response to amino acid starvation

0.64	GO:0004672	protein kinase activity
0.55	GO:0005057	signal transducer activity, downstream of receptor
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0019903	protein phosphatase binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0019904	protein domain specific binding
0.51	GO:0042803	protein homodimerization activity
0.46	GO:0000287	magnesium ion binding

0.58	GO:1990604	IRE1-TRAF2-ASK1 complex
0.53	GO:1902911	protein kinase complex
0.39	GO:0009897	external side of plasma membrane
0.37	GO:0005829	cytosol
0.33	GO:0015630	microtubule cytoskeleton

sp|Q99684|GFI1_HUMAN
Zinc finger protein Gfi-1
Search

GFI1

0.91	Growth factor independent 1 transcriptional repressor

0.82	GO:0051569	regulation of histone H3-K4 methylation
0.76	GO:0030097	hemopoiesis
0.75	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway
0.73	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity
0.68	GO:0034121	regulation of toll-like receptor signaling pathway
0.67	GO:0010977	negative regulation of neuron projection development
0.66	GO:0071222	cellular response to lipopolysaccharide
0.62	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0007422	peripheral nervous system development
0.47	GO:0034101	erythrocyte homeostasis

0.67	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0044212	transcription regulatory region DNA binding
0.49	GO:0001085	RNA polymerase II transcription factor binding

0.72	GO:0016363	nuclear matrix
0.65	GO:0017053	transcriptional repressor complex
0.63	GO:0016604	nuclear body
0.46	GO:0005667	transcription factor complex

sp|Q99685|MGLL_HUMAN
Monoglyceride lipase
Search

MGLL

0.90	Monoglyceride lipase

0.55	GO:0009966	regulation of signal transduction
0.51	GO:0006629	lipid metabolic process
0.48	GO:0051930	regulation of sensory perception of pain
0.47	GO:0006690	icosanoid metabolic process
0.46	GO:0050727	regulation of inflammatory response
0.45	GO:0060292	long term synaptic depression
0.44	GO:0030516	regulation of axon extension
0.42	GO:0072330	monocarboxylic acid biosynthetic process
0.40	GO:0044248	cellular catabolic process
0.40	GO:1901575	organic substance catabolic process

0.67	GO:0047372	acylglycerol lipase activity
0.44	GO:0042803	protein homodimerization activity
0.40	GO:0004622	lysophospholipase activity

0.65	GO:0005654	nucleoplasm
0.45	GO:0043196	varicosity
0.44	GO:0019898	extrinsic component of membrane
0.42	GO:0005829	cytosol
0.41	GO:0045202	synapse
0.39	GO:0005811	lipid droplet
0.38	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.67

EC:3.1.1.23

GO:0047372

sp|Q99687|MEIS3_HUMAN
Homeobox protein Meis3
Search

MEIS3

0.90	Meis homeobox 1 b

0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0006366	transcription by RNA polymerase II
0.56	GO:0051897	positive regulation of protein kinase B signaling
0.54	GO:2001234	negative regulation of apoptotic signaling pathway
0.52	GO:0035855	megakaryocyte development
0.52	GO:0002089	lens morphogenesis in camera-type eye
0.52	GO:0060216	definitive hemopoiesis
0.51	GO:0045638	negative regulation of myeloid cell differentiation
0.50	GO:0045665	negative regulation of neuron differentiation
0.49	GO:0007626	locomotory behavior

0.61	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0003682	chromatin binding
0.55	GO:0003677	DNA binding
0.51	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q99689|FEZ1_HUMAN
Fasciculation and elongation protein zeta-1
Search

FEZ1

0.97	Fasciculation and elongation protein zeta-1

0.85	GO:1902902	negative regulation of autophagosome assembly
0.63	GO:0007411	axon guidance
0.50	GO:0061880	regulation of anterograde axonal transport of mitochondrion
0.47	GO:0070584	mitochondrion morphogenesis
0.46	GO:0051654	establishment of mitochondrion localization
0.46	GO:0021766	hippocampus development
0.45	GO:0010976	positive regulation of neuron projection development
0.45	GO:0032388	positive regulation of intracellular transport
0.45	GO:0030010	establishment of cell polarity
0.44	GO:0051272	positive regulation of cellular component movement

0.70	GO:0043015	gamma-tubulin binding
0.46	GO:0005080	protein kinase C binding
0.46	GO:0047485	protein N-terminus binding

0.67	GO:0005813	centrosome
0.64	GO:0030424	axon
0.63	GO:0005794	Golgi apparatus
0.46	GO:0030426	growth cone
0.45	GO:0043025	neuronal cell body
0.45	GO:0030425	dendrite
0.42	GO:0005874	microtubule
0.39	GO:0005739	mitochondrion
0.37	GO:0005886	plasma membrane

sp|Q99697|PITX2_HUMAN
Pituitary homeobox 2
Search

PITX2

0.86	Pituitary homeobox 2

0.69	GO:0007275	multicellular organism development
0.57	GO:0006355	regulation of transcription, DNA-templated
0.54	GO:2000288	positive regulation of myoblast proliferation
0.54	GO:0003228	atrial cardiac muscle tissue development
0.53	GO:0060322	head development
0.52	GO:0048857	neural nucleus development
0.52	GO:0051145	smooth muscle cell differentiation
0.52	GO:0002009	morphogenesis of an epithelium
0.52	GO:0007520	myoblast fusion
0.52	GO:0043388	positive regulation of DNA binding

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001105	RNA polymerase II transcription coactivator activity
0.53	GO:0001102	RNA polymerase II activating transcription factor binding
0.51	GO:0031490	chromatin DNA binding
0.49	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.38	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.38	GO:0051219	phosphoprotein binding
0.36	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.37	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q99698|LYST_HUMAN
Lysosomal-trafficking regulator
Search

LYST

0.92	LOW QUALITY PROTEIN: lysosomal-trafficking regulator

0.84	GO:0007040	lysosome organization
0.65	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway
0.64	GO:0042267	natural killer cell mediated cytotoxicity
0.60	GO:0043473	pigmentation
0.42	GO:0033364	mast cell secretory granule organization
0.41	GO:0042832	defense response to protozoan
0.40	GO:0030595	leukocyte chemotaxis
0.39	GO:0033299	secretion of lysosomal enzymes
0.39	GO:0055091	phospholipid homeostasis
0.39	GO:0042742	defense response to bacterium

0.34	GO:0005515	protein binding
0.34	GO:0004871	signal transducer activity

0.53	GO:0015630	microtubule cytoskeleton
0.36	GO:0005829	cytosol
0.35	GO:1905360	GTPase complex
0.35	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.34	GO:0098797	plasma membrane protein complex

sp|Q99700|ATX2_HUMAN
Ataxin-2
Search

ATXN2

0.96	Ataxin-2 isoform A

0.82	GO:0034063	stress granule assembly
0.81	GO:0002091	negative regulation of receptor internalization
0.78	GO:0033962	cytoplasmic mRNA processing body assembly
0.67	GO:0010603	regulation of cytoplasmic mRNA processing body assembly
0.43	GO:0021702	cerebellar Purkinje cell differentiation
0.43	GO:0040015	negative regulation of multicellular organism growth
0.42	GO:0050905	neuromuscular process
0.41	GO:0048812	neuron projection morphogenesis
0.41	GO:0048872	homeostasis of number of cells
0.39	GO:0051236	establishment of RNA localization

0.77	GO:0005154	epidermal growth factor receptor binding
0.74	GO:0008022	protein C-terminus binding
0.49	GO:0003723	RNA binding
0.44	GO:0050692	DBD domain binding
0.41	GO:0008270	zinc ion binding

0.76	GO:0010494	cytoplasmic stress granule
0.73	GO:0005844	polysome
0.71	GO:0005802	trans-Golgi network
0.70	GO:0048471	perinuclear region of cytoplasm
0.64	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q99704|DOK1_HUMAN
Docking protein 1
Search

DOK1

0.92	Docking protein 1

0.74	GO:0007265	Ras protein signal transduction
0.71	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.42	GO:0016310	phosphorylation
0.41	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.40	GO:0007411	axon guidance
0.36	GO:0036211	protein modification process
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0044267	cellular protein metabolic process

0.71	GO:0005057	signal transducer activity, downstream of receptor
0.49	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity
0.42	GO:0016301	kinase activity

0.64	GO:0005829	cytosol
0.58	GO:0005634	nucleus
0.39	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0101003	ficolin-1-rich granule membrane
0.32	GO:0005886	plasma membrane

sp|Q99705|MCHR1_HUMAN
Melanin-concentrating hormone receptor 1
Search

MCHR1

0.97	Melanin-concentrating hormone receptor subtype 1

0.80	GO:0007218	neuropeptide signaling pathway
0.49	GO:0007631	feeding behavior
0.48	GO:0007268	chemical synaptic transmission
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.39	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.36	GO:0035645	enteric smooth muscle cell differentiation
0.36	GO:0007497	posterior midgut development
0.36	GO:0014043	negative regulation of neuron maturation
0.36	GO:0060259	regulation of feeding behavior
0.36	GO:0086100	endothelin receptor signaling pathway

0.86	GO:0030273	melanin-concentrating hormone receptor activity
0.54	GO:0008188	neuropeptide receptor activity
0.37	GO:0042923	neuropeptide binding
0.37	GO:0042562	hormone binding
0.36	GO:0005102	receptor binding
0.36	GO:0004962	endothelin receptor activity
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0004875	complement receptor activity
0.34	GO:0005525	GTP binding
0.33	GO:0004984	olfactory receptor activity

0.39	GO:0120025	plasma membrane bounded cell projection
0.37	GO:0005886	plasma membrane
0.37	GO:0097458	neuron part
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0044463	cell projection part
0.33	GO:0098857	membrane microdomain
0.33	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

sp|Q99706|KI2L4_HUMAN
Killer cell immunoglobulin-like receptor 2DL4
Search

KIR2DL4

0.97	Truncated natural killer cell inhibitory receptor

0.37	GO:0006968	cellular defense response
0.35	GO:0050776	regulation of immune response
0.33	GO:0007165	signal transduction

0.34	GO:0099600	transmembrane receptor activity
0.34	GO:0038023	signaling receptor activity
0.34	GO:0005515	protein binding

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q99707|METH_HUMAN
Methionine synthase
Search

MTR

0.53	Methionine synthase

0.71	GO:0009086	methionine biosynthetic process
0.69	GO:0042558	pteridine-containing compound metabolic process
0.62	GO:0032259	methylation
0.50	GO:0009235	cobalamin metabolic process
0.39	GO:0071732	cellular response to nitric oxide
0.39	GO:0031103	axon regeneration
0.36	GO:0061431	cellular response to methionine
0.35	GO:0050667	homocysteine metabolic process
0.34	GO:0006305	DNA alkylation
0.34	GO:0044728	DNA methylation or demethylation

0.79	GO:0008705	methionine synthase activity
0.74	GO:0031419	cobalamin binding
0.62	GO:0008270	zinc ion binding
0.35	GO:0005542	folic acid binding
0.34	GO:0016597	amino acid binding
0.33	GO:0005515	protein binding

0.50	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79	EC:2.1.1.13	GO:0008705
0.79	KEGG:R00946	GO:0008705

sp|Q99708|CTIP_HUMAN
DNA endonuclease RBBP8
Search

RBBP8

0.89	RB binding protein 8, endonuclease

0.86	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing
0.79	GO:0001835	blastocyst hatching
0.78	GO:0031572	G2 DNA damage checkpoint
0.77	GO:0000724	double-strand break repair via homologous recombination
0.75	GO:0000082	G1/S transition of mitotic cell cycle
0.71	GO:0000122	negative regulation of transcription by RNA polymerase II
0.66	GO:0006289	nucleotide-excision repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.79	GO:0001103	RNA polymerase II repressing transcription factor binding
0.78	GO:0001106	RNA polymerase II transcription corepressor activity
0.76	GO:0000014	single-stranded DNA endodeoxyribonuclease activity
0.67	GO:0042802	identical protein binding
0.66	GO:0003684	damaged DNA binding

0.73	GO:0017053	transcriptional repressor complex
0.64	GO:0005654	nucleoplasm

sp|Q99712|KCJ15_HUMAN
ATP-sensitive inward rectifier potassium channel 15
Search

KCNJ15

0.97	ATP-sensitive inward rectifier potassium channel 15

0.76	GO:0034765	regulation of ion transmembrane transport
0.70	GO:0006813	potassium ion transport
0.60	GO:0098655	cation transmembrane transport
0.50	GO:0051933	amino acid neurotransmitter reuptake
0.49	GO:0060075	regulation of resting membrane potential
0.49	GO:0098712	L-glutamate import across plasma membrane
0.48	GO:0022010	central nervous system myelination
0.48	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.48	GO:0007628	adult walking behavior
0.47	GO:0055075	potassium ion homeostasis

0.82	GO:0005242	inward rectifier potassium channel activity
0.36	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0016323	basolateral plasma membrane
0.45	GO:0098793	presynapse
0.44	GO:0005887	integral component of plasma membrane
0.35	GO:0097449	astrocyte projection
0.34	GO:0005902	microvillus
0.34	GO:0016324	apical plasma membrane

sp|Q99714|HCD2_HUMAN
3-hydroxyacyl-CoA dehydrogenase type-2
Search

HSD17B10

0.88	Hydroxyacyl-Coenzyme A dehydrogenase, type II

0.58	GO:0097745	mitochondrial tRNA 5'-end processing
0.57	GO:1990180	mitochondrial tRNA 3'-end processing
0.56	GO:0070901	mitochondrial tRNA methylation
0.54	GO:0051289	protein homotetramerization
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0007005	mitochondrion organization
0.35	GO:0033327	Leydig cell differentiation
0.35	GO:0009083	branched-chain amino acid catabolic process
0.35	GO:0007569	cell aging
0.34	GO:0009409	response to cold

0.57	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.51	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.47	GO:0000049	tRNA binding
0.42	GO:0047015	3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
0.37	GO:0008709	cholate 7-alpha-dehydrogenase activity
0.37	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.37	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.37	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.36	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.36	GO:0018454	acetoacetyl-CoA reductase activity

0.57	GO:0030678	mitochondrial ribonuclease P complex
0.37	GO:0005759	mitochondrial matrix
0.35	GO:0009295	nucleoid
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0019866	organelle inner membrane
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0005886	plasma membrane

0.57	EC:1.1.1.51	GO:0030283
0.37	KEGG:R02792	GO:0008709

sp|Q99715|COCA1_HUMAN
Collagen alpha-1(XII) chain
Search

0.63	Collagen type XII alpha 1 chain

0.50	GO:0035987	endodermal cell differentiation
0.37	GO:0007155	cell adhesion
0.34	GO:0030574	collagen catabolic process
0.34	GO:0030199	collagen fibril organization
0.33	GO:0001501	skeletal system development

0.37

GO:0005201

extracellular matrix structural constituent

0.76	GO:0005581	collagen trimer
0.46	GO:0031012	extracellular matrix
0.46	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.33	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0044425	membrane part

sp|Q99717|SMAD5_HUMAN
Mothers against decapentaplegic homolog 5
Search

SMAD5

0.64	Mothers against decapentaplegic homolog

0.82	GO:0007179	transforming growth factor beta receptor signaling pathway
0.62	GO:0002051	osteoblast fate commitment
0.61	GO:0030509	BMP signaling pathway
0.58	GO:0045669	positive regulation of osteoblast differentiation
0.58	GO:0060395	SMAD protein signal transduction
0.58	GO:0001657	ureteric bud development
0.58	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0060348	bone development
0.57	GO:0051216	cartilage development

0.61	GO:0017151	DEAD/H-box RNA helicase binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0070410	co-SMAD binding
0.45	GO:0070878	primary miRNA binding
0.45	GO:0070411	I-SMAD binding
0.43	GO:0046982	protein heterodimerization activity
0.42	GO:0019901	protein kinase binding
0.41	GO:0042803	protein homodimerization activity

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.47	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.40	GO:0012505	endomembrane system
0.38	GO:0031090	organelle membrane
0.38	GO:0031975	envelope
0.35	GO:0071141	SMAD protein complex
0.30	GO:0016021	integral component of membrane

sp|Q99719|SEPT5_HUMAN
Septin-5
Search

SEPT5

0.97	Platelet glycoprotein Ib beta chain

0.78	GO:0017157	regulation of exocytosis
0.37	GO:0051301	cell division
0.37	GO:0007049	cell cycle
0.35	GO:0016080	synaptic vesicle targeting
0.35	GO:1902803	regulation of synaptic vesicle transport
0.35	GO:0098693	regulation of synaptic vesicle cycle
0.35	GO:0046928	regulation of neurotransmitter secretion
0.35	GO:0030382	sperm mitochondrion organization
0.34	GO:0048240	sperm capacitation
0.34	GO:1903532	positive regulation of secretion by cell

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0008832	dGTPase activity
0.34	GO:0003924	GTPase activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0005198	structural molecule activity
0.33	GO:0000287	magnesium ion binding

0.77	GO:0008021	synaptic vesicle
0.50	GO:0043195	terminal bouton
0.47	GO:0005938	cell cortex
0.40	GO:0005886	plasma membrane
0.38	GO:0005856	cytoskeleton
0.35	GO:0032154	cleavage furrow
0.35	GO:0097227	sperm annulus
0.34	GO:0043209	myelin sheath
0.34	GO:0005634	nucleus
0.33	GO:0043234	protein complex

0.34	EC:3.1.5.1	GO:0008832
0.34	KEGG:R01856	GO:0008832

sp|Q99720|SGMR1_HUMAN
Sigma non-opioid intracellular receptor 1
Search

SIGMAR1

0.97	Sigma non-opioid intracellular receptor 1

0.67	GO:0070207	protein homotrimerization
0.65	GO:0043523	regulation of neuron apoptotic process
0.47	GO:0006869	lipid transport
0.42	GO:0038003	opioid receptor signaling pathway
0.39	GO:0007399	nervous system development
0.35	GO:0009611	response to wounding
0.33	GO:0006696	ergosterol biosynthetic process

0.51	GO:0004872	receptor activity
0.39	GO:0042802	identical protein binding
0.37	GO:0004871	signal transducer activity
0.34	GO:0000247	C-8 sterol isomerase activity
0.33	GO:0008144	drug binding
0.32	GO:0003677	DNA binding

0.65	GO:0014069	postsynaptic density
0.62	GO:0005635	nuclear envelope
0.59	GO:0005783	endoplasmic reticulum
0.48	GO:0031968	organelle outer membrane
0.47	GO:0030426	growth cone
0.47	GO:0005811	lipid droplet
0.47	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.47	GO:0031410	cytoplasmic vesicle
0.46	GO:0045211	postsynaptic membrane
0.45	GO:0031984	organelle subcompartment

0.34

EC:5.3.3

GO:0000247

sp|Q99726|ZNT3_HUMAN
Zinc transporter 3
Search

SLC30A3

0.90	Solute carrier family 30 (Zinc transporter), member 3

0.77	GO:0061088	regulation of sequestering of zinc ion
0.61	GO:0098655	cation transmembrane transport
0.60	GO:0051050	positive regulation of transport
0.56	GO:0010043	response to zinc ion
0.56	GO:0006829	zinc II ion transport
0.51	GO:0032846	positive regulation of homeostatic process
0.46	GO:0098660	inorganic ion transmembrane transport
0.46	GO:0048522	positive regulation of cellular process
0.41	GO:0006882	cellular zinc ion homeostasis
0.38	GO:0003323	type B pancreatic cell development

0.61	GO:0008324	cation transmembrane transporter activity
0.46	GO:0015318	inorganic molecular entity transmembrane transporter activity

0.67	GO:0005770	late endosome
0.65	GO:0030672	synaptic vesicle membrane
0.60	GO:0043005	neuron projection
0.42	GO:0005886	plasma membrane
0.40	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q99727|TIMP4_HUMAN
Metalloproteinase inhibitor 4
Search

TIMP4

0.97	Tissue inhibitor of metalloproteinase 4

0.76	GO:0010951	negative regulation of endopeptidase activity
0.54	GO:0007219	Notch signaling pathway
0.52	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.48	GO:0034097	response to cytokine
0.47	GO:0009725	response to hormone
0.43	GO:1905049	negative regulation of metallopeptidase activity
0.40	GO:0042698	ovulation cycle
0.40	GO:0007417	central nervous system development
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:1901652	response to peptide

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.51	GO:0002020	protease binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0098770	FBXO family protein binding
0.36	GO:0005178	integrin binding
0.34	GO:0008047	enzyme activator activity
0.33	GO:0008237	metallopeptidase activity

0.66	GO:0005576	extracellular region
0.39	GO:0030017	sarcomere
0.35	GO:0009986	cell surface
0.35	GO:0030426	growth cone
0.35	GO:0043025	neuronal cell body
0.33	GO:0031982	vesicle
0.32	GO:0005634	nucleus

sp|Q99728|BARD1_HUMAN
BRCA1-associated RING domain protein 1
Search

BARD1

0.95	BRCA1-associated RING domain protein 1

0.77	GO:0043065	positive regulation of apoptotic process
0.71	GO:0016567	protein ubiquitination
0.66	GO:0046826	negative regulation of protein export from nucleus
0.58	GO:0043066	negative regulation of apoptotic process
0.55	GO:0042325	regulation of phosphorylation
0.38	GO:0000732	strand displacement
0.38	GO:0031441	negative regulation of mRNA 3'-end processing
0.37	GO:0000729	DNA double-strand break processing
0.37	GO:1901796	regulation of signal transduction by p53 class mediator
0.37	GO:0007050	cell cycle arrest

0.56	GO:0042803	protein homodimerization activity
0.56	GO:0046982	protein heterodimerization activity
0.55	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0003723	RNA binding
0.36	GO:0019900	kinase binding
0.35	GO:0046872	metal ion binding
0.34	GO:0016874	ligase activity

0.85	GO:0031436	BRCA1-BARD1 complex
0.62	GO:0070531	BRCA1-A complex
0.59	GO:0016607	nuclear speck
0.58	GO:0036464	cytoplasmic ribonucleoprotein granule

0.34	EC:6	GO:0016874
0.55	KEGG:R03876	GO:0004842

sp|Q99729|ROAA_HUMAN
Heterogeneous nuclear ribonucleoprotein A/B
Search

HNRNPAB

0.95	Heterogeneous nuclear ribonucleoprotein A/Bb

0.38	GO:0001837	epithelial to mesenchymal transition
0.36	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:1904580	regulation of intracellular mRNA localization
0.35	GO:0071230	cellular response to amino acid stimulus
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.35	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003690	double-stranded DNA binding
0.34	GO:0044877	macromolecular complex binding

0.60	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.48	GO:0005654	nucleoplasm
0.36	GO:0090575	RNA polymerase II transcription factor complex
0.35	GO:0120111	neuron projection cytoplasm
0.35	GO:0030425	dendrite
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q99731|CCL19_HUMAN
C-C motif chemokine 19
Search

CCL19

0.70	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.74	GO:2000669	negative regulation of dendritic cell apoptotic process
0.74	GO:0001768	establishment of T cell polarity
0.74	GO:0010469	regulation of receptor activity
0.72	GO:0071731	response to nitric oxide
0.72	GO:0034695	response to prostaglandin E
0.72	GO:0036336	dendritic cell migration
0.71	GO:0042346	positive regulation of NF-kappaB import into nucleus
0.71	GO:0090023	positive regulation of neutrophil chemotaxis

0.84	GO:0008009	chemokine activity
0.75	GO:0031735	CCR10 chemokine receptor binding
0.47	GO:0031732	CCR7 chemokine receptor binding

0.71	GO:0005615	extracellular space
0.40	GO:0009897	external side of plasma membrane
0.34	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q99732|LITAF_HUMAN
Lipopolysaccharide-induced tumor necrosis factor-alpha factor
Search

LITAF

0.89	Lipopolysaccharide-induced tumor necrosis factor-alpha factor

0.75	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.70	GO:0071222	cellular response to lipopolysaccharide
0.67	GO:0001817	regulation of cytokine production
0.65	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.44	GO:0007568	aging
0.40	GO:0007165	signal transduction
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0001816	cytokine production
0.36	GO:0019953	sexual reproduction

0.76	GO:0050699	WW domain binding
0.69	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0008270	zinc ion binding
0.42	GO:0004871	signal transducer activity
0.39	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0005125	cytokine activity
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.35	GO:0005319	lipid transporter activity

0.80	GO:0098560	cytoplasmic side of late endosome membrane
0.80	GO:0098559	cytoplasmic side of early endosome membrane
0.79	GO:0098574	cytoplasmic side of lysosomal membrane
0.66	GO:0009898	cytoplasmic side of plasma membrane
0.63	GO:0005794	Golgi apparatus
0.63	GO:0005654	nucleoplasm
0.62	GO:0005829	cytosol
0.42	GO:0031984	organelle subcompartment
0.36	GO:0005576	extracellular region
0.33	GO:0031966	mitochondrial membrane

sp|Q99733|NP1L4_HUMAN
Nucleosome assembly protein 1-like 4
Search

NAP1L4

0.90	Nucleosome assembly protein 1 like 4

0.79	GO:0006334	nucleosome assembly
0.38	GO:0071346	cellular response to interferon-gamma
0.36	GO:0001878	response to yeast
0.34	GO:0002244	hematopoietic progenitor cell differentiation

0.54	GO:0031491	nucleosome binding
0.34	GO:0051082	unfolded protein binding
0.34	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite

sp|Q99735|MGST2_HUMAN
Microsomal glutathione S-transferase 2
Search

MGST2

0.97	Microsomal glutathione S-transferase 2

0.85	GO:0006691	leukotriene metabolic process
0.71	GO:0043085	positive regulation of catalytic activity
0.66	GO:0046456	icosanoid biosynthetic process
0.64	GO:0046466	membrane lipid catabolic process
0.61	GO:0006750	glutathione biosynthetic process
0.55	GO:0098869	cellular oxidant detoxification
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:1901685	glutathione derivative metabolic process
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0050729	positive regulation of inflammatory response

0.73	GO:0008047	enzyme activator activity
0.71	GO:0004464	leukotriene-C4 synthase activity
0.62	GO:0004364	glutathione transferase activity
0.62	GO:0004602	glutathione peroxidase activity
0.35	GO:0005515	protein binding

0.47	GO:0005635	nuclear envelope
0.46	GO:0005886	plasma membrane
0.45	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.71	EC:4.4.1.20	GO:0004464
0.71	KEGG:R03059	GO:0004464

sp|Q99741|CDC6_HUMAN
Cell division control protein 6 homolog
Search

CDC6

0.70	Cell division control protein 6

0.72	GO:0006270	DNA replication initiation
0.65	GO:0051301	cell division
0.60	GO:0032467	positive regulation of cytokinesis
0.60	GO:0051984	positive regulation of chromosome segregation
0.58	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.55	GO:0000278	mitotic cell cycle
0.44	GO:1904117	cellular response to vasopressin
0.42	GO:1904385	cellular response to angiotensin
0.42	GO:0048146	positive regulation of fibroblast proliferation
0.41	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity

0.56	GO:0019900	kinase binding
0.46	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0008144	drug binding
0.40	GO:0003779	actin binding
0.37	GO:0003682	chromatin binding

0.60	GO:0051233	spindle midzone
0.58	GO:0005634	nucleus
0.57	GO:0000922	spindle pole
0.36	GO:0043233	organelle lumen
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q99742|NPAS1_HUMAN
Neuronal PAS domain-containing protein 1
Search

NPAS1

0.97	Neuronal PAS domain-containing protein 1

0.64	GO:0042711	maternal behavior
0.63	GO:0001964	startle response
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0010468	regulation of gene expression
0.52	GO:0051253	negative regulation of RNA metabolic process
0.52	GO:0010558	negative regulation of macromolecule biosynthetic process
0.52	GO:0031327	negative regulation of cellular biosynthetic process
0.46	GO:0032502	developmental process

0.66	GO:0046983	protein dimerization activity
0.48	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.39	GO:0003677	DNA binding

0.60	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005667	transcription factor complex

sp|Q99743|NPAS2_HUMAN
Neuronal PAS domain-containing protein 2
Search

NPAS2

0.95	Neuronal PAS domain-containing protein 2

0.61	GO:0045739	positive regulation of DNA repair
0.59	GO:0051775	response to redox state
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0060548	negative regulation of cell death
0.56	GO:0010468	regulation of gene expression
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0007623	circadian rhythm
0.39	GO:0007622	rhythmic behavior

0.67	GO:0046983	protein dimerization activity
0.61	GO:0051879	Hsp90 protein binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0003677	DNA binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0046872	metal ion binding
0.32	GO:0003735	structural constituent of ribosome

0.73	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome

sp|Q99747|SNAG_HUMAN
Gamma-soluble NSF attachment protein
Search

NAPG

0.94	N-ethylmaleimide-sensitive factor attachment protein, gamma a

0.69	GO:0006886	intracellular protein transport
0.43	GO:0061025	membrane fusion
0.36	GO:0016192	vesicle-mediated transport
0.35	GO:0050821	protein stabilization
0.34	GO:0006461	protein complex assembly

0.51	GO:0005483	soluble NSF attachment protein activity
0.48	GO:0019905	syntaxin binding

0.51	GO:0043209	myelin sheath
0.48	GO:0031201	SNARE complex
0.47	GO:0005774	vacuolar membrane
0.44	GO:0005739	mitochondrion
0.38	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q99748|NRTN_HUMAN
Neurturin
Search

NRTN

0.97

Neurturin

0.76	GO:0010469	regulation of receptor activity
0.71	GO:0001755	neural crest cell migration
0.69	GO:0021675	nerve development
0.65	GO:0031175	neuron projection development
0.64	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.39	GO:0000165	MAPK cascade
0.39	GO:0048667	cell morphogenesis involved in neuron differentiation
0.39	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.38	GO:0006935	chemotaxis

0.78	GO:0008083	growth factor activity
0.39	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.66	GO:0005576	extracellular region
0.47	GO:0030424	axon
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q99750|MDFI_HUMAN
MyoD family inhibitor
Search

MDFI

0.96	MyoD family inhibitor (Predicted)

0.75	GO:0060707	trophoblast giant cell differentiation
0.73	GO:0048704	embryonic skeletal system morphogenesis
0.61	GO:0045892	negative regulation of transcription, DNA-templated
0.60	GO:0042308	negative regulation of protein import into nucleus
0.48	GO:0050434	positive regulation of viral transcription
0.45	GO:0030111	regulation of Wnt signaling pathway
0.44	GO:0007257	activation of JUN kinase activity
0.44	GO:0009950	dorsal/ventral axis specification
0.44	GO:0043392	negative regulation of DNA binding
0.41	GO:0009968	negative regulation of signal transduction

0.63	GO:0042802	identical protein binding
0.58	GO:0008134	transcription factor binding
0.39	GO:0030332	cyclin binding
0.36	GO:0050825	ice binding

0.53	GO:0005634	nucleus
0.49	GO:0043233	organelle lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm

sp|Q99755|PI51A_HUMAN
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
Search

PIP5K1A

0.67	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.53	GO:0048041	focal adhesion assembly
0.53	GO:0010761	fibroblast migration
0.52	GO:0097178	ruffle assembly
0.51	GO:0090630	activation of GTPase activity
0.50	GO:0072659	protein localization to plasma membrane
0.50	GO:0060326	cell chemotaxis
0.48	GO:0031532	actin cytoskeleton reorganization
0.48	GO:0006661	phosphatidylinositol biosynthetic process
0.38	GO:0006897	endocytosis

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0019900	kinase binding
0.38	GO:0052813	phosphatidylinositol bisphosphate kinase activity
0.37	GO:0052810	1-phosphatidylinositol-5-kinase activity

0.51	GO:0032587	ruffle membrane
0.50	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.50	GO:0030027	lamellipodium
0.49	GO:0016607	nuclear speck
0.45	GO:0005829	cytosol
0.36	GO:0005925	focal adhesion
0.36	GO:0005747	mitochondrial respiratory chain complex I
0.34	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0016307

sp|Q99757|THIOM_HUMAN
Thioredoxin, mitochondrial
Search

TXN2

0.38	Mitochondrial thioredoxin

0.74	GO:0006662	glycerol ether metabolic process
0.68	GO:0045454	cell redox homeostasis
0.52	GO:0055114	oxidation-reduction process
0.39	GO:0048678	response to axon injury
0.39	GO:0009749	response to glucose
0.38	GO:0001666	response to hypoxia
0.38	GO:0031669	cellular response to nutrient levels
0.37	GO:0014070	response to organic cyclic compound
0.37	GO:0009725	response to hormone
0.37	GO:0006979	response to oxidative stress

0.71	GO:0015035	protein disulfide oxidoreductase activity
0.38	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.38	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.37	GO:0032403	protein complex binding
0.33	GO:0098808	mRNA cap binding
0.33	GO:0047134	protein-disulfide reductase activity
0.32	GO:0004791	thioredoxin-disulfide reductase activity
0.32	GO:0003743	translation initiation factor activity

0.48	GO:0005730	nucleolus
0.43	GO:0005739	mitochondrion
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.33	GO:0016282	eukaryotic 43S preinitiation complex
0.33	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0005852	eukaryotic translation initiation factor 3 complex

0.38	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.38	KEGG:R07607	GO:0033743

sp|Q99758|ABCA3_HUMAN
ATP-binding cassette sub-family A member 3
Search

ABCA3

0.81	ATP-binding cassette sub-family A member 3

0.55	GO:0055085	transmembrane transport
0.51	GO:0006869	lipid transport
0.46	GO:0006638	neutral lipid metabolic process
0.41	GO:0051384	response to glucocorticoid
0.35	GO:0042493	response to drug
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005319	lipid transporter activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003677	DNA binding

0.63	GO:0097233	alveolar lamellar body membrane
0.44	GO:0043231	intracellular membrane-bounded organelle
0.43	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|Q99759|M3K3_HUMAN
Mitogen-activated protein kinase kinase kinase 3
Search

MAP3K3

0.89	Mitogen-activated protein kinase kinase kinase 3

0.63	GO:0006468	protein phosphorylation
0.52	GO:0071864	positive regulation of cell proliferation in bone marrow
0.51	GO:2000773	negative regulation of cellular senescence
0.51	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.50	GO:1900745	positive regulation of p38MAPK cascade
0.50	GO:0072359	circulatory system development
0.49	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.46	GO:0031098	stress-activated protein kinase signaling cascade
0.46	GO:0032147	activation of protein kinase activity
0.44	GO:0007346	regulation of mitotic cell cycle

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0019901	protein kinase binding
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0046872	metal ion binding

0.40	GO:0005829	cytosol
0.40	GO:0005654	nucleoplasm

sp|Q99766|ATP5S_HUMAN
ATP synthase subunit s, mitochondrial
Search

ATP5S

0.95	ATP synthase subunit s, mitochondrial

0.51	GO:0006754	ATP biosynthetic process
0.47	GO:0015992	proton transport
0.43	GO:0042407	cristae formation
0.41	GO:0006839	mitochondrial transport
0.39	GO:0046907	intracellular transport
0.38	GO:0098662	inorganic cation transmembrane transport

0.42	GO:0046872	metal ion binding
0.38	GO:0015078	hydrogen ion transmembrane transporter activity

0.60	GO:0005739	mitochondrion
0.51	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.46	GO:0019866	organelle inner membrane

sp|Q99767|APBA2_HUMAN
Amyloid beta A4 precursor protein-binding family A member 2
Search

APBA2

0.97	Amyloid beta precursor protein binding family A member 2

0.77	GO:0007268	chemical synaptic transmission
0.56	GO:0035264	multicellular organism growth
0.54	GO:0007626	locomotory behavior
0.51	GO:0001701	in utero embryonic development
0.42	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0015031	protein transport
0.36	GO:0006461	protein complex assembly
0.35	GO:0017156	calcium ion regulated exocytosis
0.35	GO:0048489	synaptic vesicle transport
0.35	GO:0099504	synaptic vesicle cycle

0.85	GO:0001540	amyloid-beta binding
0.36	GO:0005515	protein binding
0.36	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.81	GO:0008021	synaptic vesicle
0.35	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol

sp|Q99784|NOE1_HUMAN
Noelin
Search

OLFM1

0.97	Olfactomedin 1

0.74	GO:0007399	nervous system development
0.51	GO:0003190	atrioventricular valve formation
0.50	GO:0060317	cardiac epithelial to mesenchymal transition
0.49	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.44	GO:0010628	positive regulation of gene expression
0.43	GO:0010629	negative regulation of gene expression
0.40	GO:0023041	neuronal signal transduction
0.39	GO:0061387	regulation of extent of cell growth
0.38	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.38	GO:0048638	regulation of developmental growth

0.37	GO:0001540	amyloid-beta binding
0.34	GO:0005515	protein binding

0.39	GO:0044295	axonal growth cone
0.39	GO:0043204	perikaryon
0.37	GO:0045202	synapse
0.37	GO:0030054	cell junction
0.37	GO:0005615	extracellular space
0.37	GO:0032281	AMPA glutamate receptor complex
0.37	GO:0005783	endoplasmic reticulum
0.35	GO:0098590	plasma membrane region

sp|Q99788|CML1_HUMAN
Chemokine-like receptor 1
Search

CMKLR1

0.90	Seven transmembrane helix receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.58	GO:0032695	negative regulation of interleukin-12 production
0.56	GO:0010759	positive regulation of macrophage chemotaxis
0.56	GO:0045600	positive regulation of fat cell differentiation
0.54	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.54	GO:0050848	regulation of calcium-mediated signaling
0.49	GO:0006935	chemotaxis
0.41	GO:0002430	complement receptor mediated signaling pathway
0.38	GO:0002283	neutrophil activation involved in immune response
0.38	GO:0050900	leukocyte migration

0.72	GO:0004930	G-protein coupled receptor activity
0.42	GO:0001653	peptide receptor activity
0.41	GO:0004875	complement receptor activity
0.35	GO:0004896	cytokine receptor activity
0.35	GO:0005124	scavenger receptor binding
0.34	GO:0050786	RAGE receptor binding
0.33	GO:0004749	ribose phosphate diphosphokinase activity
0.33	GO:0001847	opsonin receptor activity
0.33	GO:0000287	magnesium ion binding

0.42	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.33	EC:2.7.6.1	GO:0004749
0.33	KEGG:R01049	GO:0004749

sp|Q99795|GPA33_HUMAN
Cell surface A33 antigen
Search

GPA33

0.93	Neuronal growth regulator 1 (Fragment)

0.34	GO:0090557	establishment of endothelial intestinal barrier
0.33	GO:0050892	intestinal absorption
0.33	GO:0034260	negative regulation of GTPase activity
0.33	GO:2000249	regulation of actin cytoskeleton reorganization
0.33	GO:0090559	regulation of membrane permeability
0.33	GO:0072659	protein localization to plasma membrane
0.33	GO:0031032	actomyosin structure organization
0.33	GO:0043547	positive regulation of GTPase activity

0.35	GO:0005515	protein binding
0.35	GO:0004872	receptor activity
0.32	GO:0005509	calcium ion binding

0.40	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane
0.33	GO:0030054	cell junction
0.33	GO:0005604	basement membrane
0.32	GO:0005938	cell cortex
0.30	GO:0016021	integral component of membrane

sp|Q99797|MIPEP_HUMAN
Mitochondrial intermediate peptidase
Search

MIPEP

0.82	Mitochondrial intermediate peptidase

0.83	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.40	GO:0006518	peptide metabolic process

0.70	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding

0.75	GO:0005759	mitochondrial matrix
0.30	GO:0044425	membrane part

0.70

GO:0004222

sp|Q99798|ACON_HUMAN
Aconitate hydratase, mitochondrial
Search

ACO2

0.70	Aconitate hydratase, mitochondrial

0.68	GO:0006099	tricarboxylic acid cycle
0.39	GO:0035900	response to isolation stress
0.38	GO:0001889	liver development
0.37	GO:0006102	isocitrate metabolic process

0.76	GO:0003994	aconitate hydratase activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.38	GO:0051538	3 iron, 4 sulfur cluster binding
0.33	GO:0005515	protein binding

0.58	GO:0005739	mitochondrion
0.51	GO:0043209	myelin sheath
0.35	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.76

EC:4.2.1.3

GO:0003994

sp|Q99801|NKX31_HUMAN
Homeobox protein Nkx-3.1
Search

NKX3-1

0.97	Homeobox protein zampogna

0.62	GO:2000836	positive regulation of androgen secretion
0.61	GO:0071898	regulation of estrogen receptor binding
0.59	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis
0.59	GO:1900121	negative regulation of receptor binding
0.59	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development
0.59	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
0.59	GO:0060442	branching involved in prostate gland morphogenesis
0.58	GO:0033574	response to testosterone
0.58	GO:0030521	androgen receptor signaling pathway
0.58	GO:0043491	protein kinase B signaling

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0097162	MADS box domain binding
0.59	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.59	GO:0004882	androgen receptor activity
0.58	GO:0030284	estrogen receptor activity
0.58	GO:0030331	estrogen receptor binding
0.57	GO:0043621	protein self-association
0.56	GO:0042826	histone deacetylase binding
0.56	GO:0030295	protein kinase activator activity
0.56	GO:0001047	core promoter binding

0.61	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005576	extracellular region
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q99805|TM9S2_HUMAN
Transmembrane 9 superfamily member 2
Search

TM9SF2

0.54	Transmembrane 9 superfamily member

0.38	GO:0010008	endosome membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

sp|Q99807|COQ7_HUMAN
5-demethoxyubiquinone hydroxylase, mitochondrial
Search

COQ7

0.73	Ubiquinone biosynthesis protein COQ7 (Fragment)

0.75	GO:0006744	ubiquinone biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.35	GO:0006468	protein phosphorylation
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.37	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0031314	extrinsic component of mitochondrial inner membrane
0.30	GO:0016021	integral component of membrane

0.37

EC:1.14.13

GO:0016709

sp|Q99808|S29A1_HUMAN
Equilibrative nucleoside transporter 1
Search

SLC29A1

0.90	NBMPR-sensitive equilibrative nucleoside transporter

0.79	GO:1901642	nucleoside transmembrane transport
0.40	GO:0015862	uridine transport
0.39	GO:0007595	lactation
0.39	GO:0030431	sleep
0.39	GO:0071333	cellular response to glucose stimulus
0.38	GO:0071456	cellular response to hypoxia
0.38	GO:0060079	excitatory postsynaptic potential
0.32	GO:0006457	protein folding
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process

0.78	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0051082	unfolded protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0005887	integral component of plasma membrane
0.53	GO:0016323	basolateral plasma membrane
0.53	GO:0016324	apical plasma membrane
0.37	GO:0098794	postsynapse

sp|Q99811|PRRX2_HUMAN
Paired mesoderm homeobox protein 2
Search

PRRX2

0.97	Paired mesoderm homeobox protein 2

0.68	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:1904888	cranial skeletal system development
0.44	GO:0002053	positive regulation of mesenchymal cell proliferation
0.44	GO:0045880	positive regulation of smoothened signaling pathway
0.44	GO:0009888	tissue development
0.42	GO:0010604	positive regulation of macromolecule metabolic process
0.41	GO:0006366	transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.44	GO:0071837	HMG box domain binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0001105	RNA polymerase II transcription coactivator activity
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part

sp|Q99814|EPAS1_HUMAN
Endothelial PAS domain-containing protein 1
Search

EPAS1

0.97	Endothelial PAS domain-containing protein 1

0.60	GO:0048625	myoblast fate commitment
0.60	GO:0043129	surfactant homeostasis
0.59	GO:0042415	norepinephrine metabolic process
0.58	GO:0001974	blood vessel remodeling
0.58	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress
0.57	GO:0071456	cellular response to hypoxia
0.57	GO:0002027	regulation of heart rate
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0030218	erythrocyte differentiation
0.56	GO:0030324	lung development

0.67	GO:0046983	protein dimerization activity
0.59	GO:0035035	histone acetyltransferase binding
0.59	GO:0003700	DNA binding transcription factor activity
0.51	GO:0008134	transcription factor binding
0.47	GO:0043565	sequence-specific DNA binding
0.35	GO:0050897	cobalt ion binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding
0.32	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003690	double-stranded DNA binding

0.71	GO:0005667	transcription factor complex
0.60	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.47	GO:0005737	cytoplasm
0.43	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q99816|TS101_HUMAN
Tumor susceptibility gene 101 protein
Search

TSG101

0.92	Tumor susceptibility protein 101

0.65	GO:0015031	protein transport
0.60	GO:0036211	protein modification process
0.58	GO:2000395	regulation of ubiquitin-dependent endocytosis
0.58	GO:1903774	positive regulation of viral budding via host ESCRT complex
0.57	GO:1990182	exosomal secretion
0.57	GO:1903551	regulation of extracellular exosome assembly
0.56	GO:1903543	positive regulation of exosomal secretion
0.56	GO:1902188	positive regulation of viral release from host cell
0.56	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.55	GO:0044267	cellular protein metabolic process

0.57	GO:0046790	virion binding
0.54	GO:0048306	calcium-dependent protein binding
0.52	GO:0003714	transcription corepressor activity
0.52	GO:0043130	ubiquitin binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0032403	protein complex binding
0.39	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.32	GO:0003677	DNA binding

0.53	GO:0000813	ESCRT I complex
0.52	GO:0070062	extracellular exosome
0.52	GO:0005770	late endosome
0.52	GO:0005769	early endosome
0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.38	GO:0090543	Flemming body
0.36	GO:0005815	microtubule organizing center
0.33	GO:0044216	other organism cell

0.33

GO:0016616

sp|Q99819|GDIR3_HUMAN
Rho GDP-dissociation inhibitor 3
Search

ARHGDIG

0.88	Rho GDP dissociation inhibitor gamma

0.69	GO:0050790	regulation of catalytic activity
0.50	GO:0032879	regulation of localization
0.46	GO:2000249	regulation of actin cytoskeleton reorganization
0.44	GO:2000242	negative regulation of reproductive process
0.44	GO:0043901	negative regulation of multi-organism process
0.44	GO:0040013	negative regulation of locomotion
0.43	GO:0051056	regulation of small GTPase mediated signal transduction
0.43	GO:0051093	negative regulation of developmental process
0.43	GO:0051241	negative regulation of multicellular organismal process
0.42	GO:2000026	regulation of multicellular organismal development

0.85	GO:0005094	Rho GDP-dissociation inhibitor activity
0.45	GO:0048365	Rac GTPase binding
0.40	GO:0003924	GTPase activity
0.38	GO:0005096	GTPase activator activity
0.32	GO:0003723	RNA binding
0.32	GO:0016853	isomerase activity

0.49	GO:0005737	cytoplasm
0.40	GO:0005886	plasma membrane
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0043229	intracellular organelle
0.35	GO:0005615	extracellular space
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0044425	membrane part

0.32

EC:5

GO:0016853

sp|Q99828|CIB1_HUMAN
Calcium and integrin-binding protein 1
Search

CIB1

0.96	Calcium and integrin-binding protein 1

0.67	GO:0007229	integrin-mediated signaling pathway
0.59	GO:2000256	positive regulation of male germ cell proliferation
0.59	GO:0106058	positive regulation of calcineurin-mediated signaling
0.58	GO:0038163	thrombopoietin-mediated signaling pathway
0.58	GO:0007113	endomitotic cell cycle
0.58	GO:0045653	negative regulation of megakaryocyte differentiation
0.58	GO:0070884	regulation of calcineurin-NFAT signaling cascade
0.57	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.57	GO:1990090	cellular response to nerve growth factor stimulus
0.57	GO:0090314	positive regulation of protein targeting to membrane

0.70	GO:0005509	calcium ion binding
0.59	GO:0008427	calcium-dependent protein kinase inhibitor activity
0.57	GO:0043495	protein membrane anchor
0.55	GO:0030291	protein serine/threonine kinase inhibitor activity
0.54	GO:0044325	ion channel binding
0.51	GO:0017016	Ras GTPase binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.37	GO:0019901	protein kinase binding
0.33	GO:0030554	adenyl nucleotide binding

0.57	GO:0032433	filopodium tip
0.56	GO:0042383	sarcolemma
0.55	GO:0030426	growth cone
0.54	GO:0030027	lamellipodium
0.53	GO:0043025	neuronal cell body
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005813	centrosome
0.48	GO:0005654	nucleoplasm
0.48	GO:0005783	endoplasmic reticulum
0.41	GO:0032587	ruffle membrane

0.37	EC:2.7.1.158	GO:0035299
0.37	KEGG:R05202	GO:0035299

sp|Q99829|CPNE1_HUMAN
Copine-1
Search

CPNE1

0.89	RNA-binding protein 12

0.54	GO:0071277	cellular response to calcium ion
0.49	GO:0038128	ERBB2 signaling pathway
0.48	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.47	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.46	GO:0043392	negative regulation of DNA binding
0.46	GO:0051897	positive regulation of protein kinase B signaling
0.46	GO:1990138	neuron projection extension
0.46	GO:0030335	positive regulation of cell migration
0.45	GO:0071363	cellular response to growth factor stimulus
0.45	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling

0.49	GO:0005543	phospholipid binding
0.48	GO:0048306	calcium-dependent protein binding
0.47	GO:0030971	receptor tyrosine kinase binding
0.47	GO:0051059	NF-kappaB binding
0.46	GO:0003723	RNA binding
0.43	GO:0042803	protein homodimerization activity
0.43	GO:0072341	modified amino acid binding
0.43	GO:0004674	protein serine/threonine kinase activity
0.41	GO:0005509	calcium ion binding
0.40	GO:0004175	endopeptidase activity

0.69	GO:0031965	nuclear membrane
0.62	GO:0031981	nuclear lumen
0.46	GO:0005829	cytosol
0.46	GO:0005925	focal adhesion
0.44	GO:0070062	extracellular exosome
0.42	GO:0005886	plasma membrane
0.41	GO:0035577	azurophil granule membrane
0.40	GO:0005739	mitochondrion
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0004674

sp|Q99832|TCPH_HUMAN
T-complex protein 1 subunit eta
Search

CCT7

0.90	Chaperonin containing TCP1 subunit 7

0.69	GO:0006457	protein folding
0.65	GO:1904869	regulation of protein localization to Cajal body
0.65	GO:1904851	positive regulation of establishment of protein localization to telomere
0.64	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.63	GO:0032212	positive regulation of telomere maintenance via telomerase
0.61	GO:1900182	positive regulation of protein localization to nucleus
0.60	GO:0007339	binding of sperm to zona pellucida
0.59	GO:0050821	protein stabilization
0.57	GO:1901998	toxin transport

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0042802	identical protein binding
0.52	GO:0044183	protein binding involved in protein folding

0.64	GO:0005832	chaperonin-containing T-complex
0.62	GO:0002199	zona pellucida receptor complex
0.57	GO:0044297	cell body
0.55	GO:0005874	microtubule
0.46	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome

sp|Q99835|SMO_HUMAN
Smoothened homolog
Search

SMO

0.97	Smoothened, frizzled class receptor

0.83	GO:0007224	smoothened signaling pathway
0.67	GO:0007275	multicellular organism development
0.64	GO:0060248	detection of cell density by contact stimulus involved in contact inhibition
0.63	GO:0045880	positive regulation of smoothened signaling pathway
0.62	GO:0014904	myotube cell development
0.61	GO:0048747	muscle fiber development
0.61	GO:0001708	cell fate specification
0.60	GO:0051799	negative regulation of hair follicle development
0.60	GO:0060684	epithelial-mesenchymal cell signaling
0.60	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation

0.69	GO:0004888	transmembrane signaling receptor activity
0.65	GO:0005113	patched binding
0.51	GO:0017147	Wnt-protein binding
0.49	GO:0008142	oxysterol binding
0.42	GO:0008144	drug binding
0.33	GO:0046872	metal ion binding
0.33	GO:0042802	identical protein binding

0.58	GO:0005901	caveola
0.57	GO:0060170	ciliary membrane
0.51	GO:0005794	Golgi apparatus
0.38	GO:0030666	endocytic vesicle membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0044294	dendritic growth cone
0.36	GO:0097542	ciliary tip
0.36	GO:0044295	axonal growth cone
0.36	GO:0043025	neuronal cell body
0.35	GO:0014069	postsynaptic density

sp|Q99836|MYD88_HUMAN
Myeloid differentiation primary response protein MyD88
Search

MYD88

0.93	Myeloid differentiation primary response 88

0.77	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.77	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.73	GO:0006954	inflammatory response
0.58	GO:2000338	regulation of chemokine (C-X-C motif) ligand 1 production
0.58	GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus
0.58	GO:0050830	defense response to Gram-positive bacterium
0.58	GO:0032747	positive regulation of interleukin-23 production
0.58	GO:0045351	type I interferon biosynthetic process
0.57	GO:0002238	response to molecule of fungal origin
0.57	GO:0090557	establishment of endothelial intestinal barrier

0.84	GO:0070976	TIR domain binding
0.56	GO:0035325	Toll-like receptor binding
0.41	GO:0005121	Toll binding
0.40	GO:0005149	interleukin-1 receptor binding
0.38	GO:0043621	protein self-association
0.37	GO:0042802	identical protein binding
0.36	GO:0005123	death receptor binding
0.33	GO:0001875	lipopolysaccharide receptor activity
0.32	GO:0004888	transmembrane signaling receptor activity

0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.39	GO:0014069	postsynaptic density
0.35	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.35	GO:0010008	endosome membrane
0.33	GO:0046696	lipopolysaccharide receptor complex

sp|Q99848|EBP2_HUMAN
Probable rRNA-processing protein EBP2
Search

EBNA1BP2

0.95	Probable rRNA-processing protein EBP2

0.59	GO:0042273	ribosomal large subunit biogenesis
0.54	GO:0006364	rRNA processing
0.36	GO:0000723	telomere maintenance
0.35	GO:0032392	DNA geometric change
0.35	GO:0043043	peptide biosynthetic process
0.35	GO:0006310	DNA recombination
0.35	GO:0006281	DNA repair
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0009059	macromolecule biosynthetic process

0.39	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.36	GO:0003735	structural constituent of ribosome
0.35	GO:0003678	DNA helicase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005730	nucleolus
0.62	GO:0034399	nuclear periphery
0.62	GO:0030687	preribosome, large subunit precursor
0.35	GO:0005840	ribosome

sp|Q99853|FOXB1_HUMAN
Forkhead box protein B1
Search

FOXB1

0.96	forkhead box protein B1

0.63	GO:0061381	cell migration in diencephalon
0.63	GO:0061374	mammillothalamic axonal tract development
0.63	GO:0061379	inferior colliculus development
0.61	GO:0021855	hypothalamus cell migration
0.61	GO:0007412	axon target recognition
0.61	GO:0033504	floor plate development
0.59	GO:0008542	visual learning
0.59	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development
0.59	GO:0022029	telencephalon cell migration
0.58	GO:0021794	thalamus development

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q99856|ARI3A_HUMAN
AT-rich interactive domain-containing protein 3A
Search

ARID3A

0.95	AT-rich interactive domain-containing protein 3A

0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.35	GO:0007275	multicellular organism development
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.52	GO:0042803	protein homodimerization activity
0.34	GO:0004930	G-protein coupled receptor activity

0.61	GO:0005634	nucleus
0.55	GO:0045121	membrane raft
0.49	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q99865|SPI2A_HUMAN
Spindlin-2A
Search

SPIN1

0.95	Z-linked spindlin 1

0.78	GO:0007276	gamete generation
0.57	GO:0051726	regulation of cell cycle
0.47	GO:0009303	rRNA transcription
0.46	GO:0030177	positive regulation of Wnt signaling pathway
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0007049	cell cycle
0.37	GO:0016055	Wnt signaling pathway
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0007275	multicellular organism development
0.36	GO:0006915	apoptotic process

0.49	GO:0140034	methylation-dependent protein binding
0.48	GO:0042393	histone binding
0.34	GO:0018738	S-formylglutathione hydrolase activity
0.33	GO:0003677	DNA binding
0.33	GO:0052689	carboxylic ester hydrolase activity

0.52	GO:0005634	nucleus
0.44	GO:0005819	spindle
0.44	GO:0005829	cytosol
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0012505	endomembrane system
0.40	GO:0031967	organelle envelope
0.40	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:3.1.2.12	GO:0018738
0.34	KEGG:R00527	GO:0018738

sp|Q99871|HAUS7_HUMAN
HAUS augmin-like complex subunit 7
Search

HAUS7

0.96	HAUS augmin like complex subunit 7

0.81	GO:0007098	centrosome cycle
0.81	GO:0051225	spindle assembly
0.46	GO:0097711	ciliary basal body-plasma membrane docking
0.44	GO:0000086	G2/M transition of mitotic cell cycle
0.43	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.42	GO:0051301	cell division

0.86	GO:0031996	thioesterase binding
0.39	GO:0051011	microtubule minus-end binding
0.34	GO:0003676	nucleic acid binding

0.83	GO:0070652	HAUS complex
0.77	GO:0005813	centrosome
0.45	GO:0005819	spindle
0.44	GO:0005874	microtubule
0.40	GO:0005829	cytosol

sp|Q99873|ANM1_HUMAN
Protein arginine N-methyltransferase 1
Search

PRMT1

0.85	Arginine methyltransferase 1 variant 2

0.72	GO:0008213	protein alkylation
0.66	GO:0043414	macromolecule methylation
0.55	GO:0018195	peptidyl-arginine modification
0.52	GO:0016570	histone modification
0.50	GO:0009790	embryo development
0.45	GO:0060026	convergent extension
0.43	GO:0045653	negative regulation of megakaryocyte differentiation
0.40	GO:0008284	positive regulation of cell proliferation
0.39	GO:0007399	nervous system development
0.39	GO:2001141	regulation of RNA biosynthetic process

0.62	GO:0008168	methyltransferase activity
0.42	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0048273	mitogen-activated protein kinase p38 binding
0.39	GO:0008327	methyl-CpG binding
0.37	GO:0042802	identical protein binding
0.36	GO:0030519	snoRNP binding
0.36	GO:0003713	transcription coactivator activity
0.34	GO:0003723	RNA binding

0.45	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.39	GO:0034709	methylosome
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.62

GO:0008168

sp|Q99877|H2B1N_HUMAN
Histone H2B type 1-N
Search

0.92	Histone H2B type 1-N

0.53	GO:0006334	nucleosome assembly
0.37	GO:0002227	innate immune response in mucosa
0.36	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.36	GO:0019731	antibacterial humoral response
0.36	GO:0050830	defense response to Gram-positive bacterium
0.35	GO:0016567	protein ubiquitination
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.40	GO:0097677	STAT family protein binding
0.38	GO:0044389	ubiquitin-like protein ligase binding
0.35	GO:0042802	identical protein binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.46	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.37	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0043234	protein complex

sp|Q99878|H2A1J_HUMAN
Histone H2A type 1-J
Search

0.86	Histone H2A type 1-J

0.54	GO:0006342	chromatin silencing
0.34	GO:0006334	nucleosome assembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.36	GO:0019899	enzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.38	GO:0070062	extracellular exosome

sp|Q99879|H2B1M_HUMAN
Histone H2B type 1-M
Search

sp|Q99880|H2B1L_HUMAN
Histone H2B type 1-L
Search

0.92	Histone H2B type 1-L

0.52	GO:0006334	nucleosome assembly
0.38	GO:0002227	innate immune response in mucosa
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.34	GO:0050829	defense response to Gram-negative bacterium
0.34	GO:0031640	killing of cells of other organism
0.34	GO:0016567	protein ubiquitination
0.33	GO:0006352	DNA-templated transcription, initiation

0.73	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.37	GO:0097677	STAT family protein binding
0.35	GO:0044389	ubiquitin-like protein ligase binding
0.34	GO:0042802	identical protein binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.43	GO:0031974	membrane-enclosed lumen
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0043234	protein complex

sp|Q99884|SC6A7_HUMAN
Sodium-dependent proline transporter
Search

SLC6A7

0.48	Sodium-dependent proline transporter

0.76	GO:0006836	neurotransmitter transport
0.56	GO:0035524	proline transmembrane transport
0.35	GO:0089718	amino acid import across plasma membrane
0.35	GO:0043092	L-amino acid import
0.35	GO:0042752	regulation of circadian rhythm
0.35	GO:1902475	L-alpha-amino acid transmembrane transport
0.34	GO:0006855	drug transmembrane transport
0.34	GO:0001505	regulation of neurotransmitter levels
0.34	GO:0007275	multicellular organism development
0.33	GO:0015718	monocarboxylic acid transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.56	GO:0015193	L-proline transmembrane transporter activity
0.37	GO:0005283	sodium:amino acid symporter activity
0.37	GO:0015296	anion:cation symporter activity
0.35	GO:0015187	glycine transmembrane transporter activity
0.34	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity
0.34	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.33	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.33	GO:0003677	DNA binding

0.44	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

sp|Q99895|CTRC_HUMAN
Chymotrypsin-C
Search

CTRC

0.90	Pancreatic elastase

0.61	GO:0006508	proteolysis
0.42	GO:0050878	regulation of body fluid levels
0.41	GO:0043588	skin development
0.41	GO:0030104	water homeostasis
0.40	GO:0048871	multicellular organismal homeostasis
0.37	GO:0050817	coagulation
0.37	GO:0042060	wound healing
0.35	GO:0019725	cellular homeostasis
0.34	GO:0055074	calcium ion homeostasis
0.34	GO:0009913	epidermal cell differentiation

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.41	GO:0005615	extracellular space
0.38	GO:0036457	keratohyalin granule
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.69

EC:3.4.21

GO:0004252

sp|Q99909|SSX3_HUMAN
Protein SSX3
Search

0.97	SSX family member 3

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process
0.50	GO:0031327	negative regulation of cellular biosynthetic process
0.40	GO:0006351	transcription, DNA-templated

0.56	GO:0003714	transcription corepressor activity
0.50	GO:0003676	nucleic acid binding
0.39	GO:0005515	protein binding
0.38	GO:0003713	transcription coactivator activity

0.58	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q99928|GBRG3_HUMAN
Gamma-aminobutyric acid receptor subunit gamma-3
Search

0.95	Gamma-aminobutyric acid type A receptor epsilon subunit

0.81	GO:0007214	gamma-aminobutyric acid signaling pathway
0.72	GO:0006821	chloride transport
0.58	GO:0034220	ion transmembrane transport
0.37	GO:0042493	response to drug

0.80	GO:0004890	GABA-A receptor activity
0.72	GO:0005230	extracellular ligand-gated ion channel activity
0.39	GO:0005254	chloride channel activity

0.53	GO:0005886	plasma membrane
0.40	GO:0034707	chloride channel complex
0.39	GO:0098794	postsynapse
0.39	GO:0030054	cell junction

sp|Q99929|ASCL2_HUMAN
Achaete-scute homolog 2
Search

0.28	Transcriptional regulator

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0060712	spongiotrophoblast layer development
0.54	GO:0001666	response to hypoxia
0.54	GO:0030154	cell differentiation
0.53	GO:0007399	nervous system development
0.53	GO:0035019	somatic stem cell population maintenance
0.53	GO:0045892	negative regulation of transcription, DNA-templated
0.52	GO:0051960	regulation of nervous system development
0.52	GO:0060284	regulation of cell development
0.52	GO:0035270	endocrine system development

0.68	GO:0046983	protein dimerization activity
0.62	GO:0070888	E-box binding
0.60	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0043425	bHLH transcription factor binding
0.44	GO:0000989	transcription factor activity, transcription factor binding
0.44	GO:0003682	chromatin binding
0.35	GO:0042802	identical protein binding

0.49	GO:0090575	RNA polymerase II transcription factor complex
0.45	GO:0043025	neuronal cell body
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q99932|SPAG8_HUMAN
Sperm-associated antigen 8
Search

SPAG8

0.96	Sperm-associated antigen 8

0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0032092	positive regulation of protein binding
0.42	GO:0007338	single fertilization
0.41	GO:0007283	spermatogenesis
0.39	GO:0030154	cell differentiation
0.38	GO:0007049	cell cycle
0.34	GO:0016070	RNA metabolic process
0.34	GO:0032259	methylation
0.34	GO:0010467	gene expression
0.33	GO:0006468	protein phosphorylation

0.72	GO:0008017	microtubule binding
0.34	GO:0033897	ribonuclease T2 activity
0.34	GO:0008168	methyltransferase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0004969	histamine receptor activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding

0.48	GO:0005634	nucleus
0.42	GO:0001669	acrosomal vesicle
0.40	GO:0005819	spindle
0.33	GO:0042613	MHC class II protein complex
0.33	GO:0019005	SCF ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.27.1

GO:0033897

sp|Q99933|BAG1_HUMAN
BAG family molecular chaperone regulator 1
Search

BAG1

0.88	BAG family molecular chaperone regulator 1

0.41	GO:0051085	chaperone cofactor-dependent protein refolding
0.40	GO:0043066	negative regulation of apoptotic process
0.40	GO:2000671	regulation of motor neuron apoptotic process
0.40	GO:0006915	apoptotic process
0.39	GO:0043525	positive regulation of neuron apoptotic process
0.38	GO:1901215	negative regulation of neuron death
0.38	GO:1900034	regulation of cellular response to heat
0.38	GO:0050790	regulation of catalytic activity
0.37	GO:0070585	protein localization to mitochondrion
0.37	GO:0030182	neuron differentiation

0.77	GO:0051087	chaperone binding
0.40	GO:0000774	adenyl-nucleotide exchange factor activity
0.38	GO:0051219	phosphoprotein binding
0.36	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0038048	dynorphin receptor activity
0.34	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.34	GO:0004333	fumarate hydratase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.38	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005739	mitochondrion
0.34	GO:0045239	tricarboxylic acid cycle enzyme complex
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.34	EC:1.3.5.1	GO:0008177
0.34	KEGG:R02164	GO:0008177

sp|Q99935|PROL1_HUMAN
Opiorphin prepropeptide
Search

OPRPN

0.96	Opiorphin prepropeptide

0.85	GO:0051930	regulation of sensory perception of pain
0.74	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:0001895	retina homeostasis
0.41	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004866	endopeptidase inhibitor activity
0.41	GO:0004930	G-protein coupled receptor activity

0.65	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q99941|ATF6B_HUMAN
Cyclic AMP-dependent transcription factor ATF-6 beta
Search

ATF6B

0.97	Cyclic AMP-dependent transcription factor ATF-6 beta

0.84	GO:0030968	endoplasmic reticulum unfolded protein response
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0043620	regulation of DNA-templated transcription in response to stress
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0001654	eye development
0.37	GO:0043065	positive regulation of apoptotic process
0.37	GO:0007601	visual perception
0.37	GO:0006984	ER-nucleus signaling pathway
0.36	GO:0045014	negative regulation of transcription by glucose
0.36	GO:0006366	transcription by RNA polymerase II

0.85	GO:0035497	cAMP response element binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.33	GO:0003713	transcription coactivator activity

0.67	GO:0012505	endomembrane system
0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.52	GO:0031984	organelle subcompartment
0.51	GO:0032993	protein-DNA complex
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0044444	cytoplasmic part
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0005615	extracellular space
0.35	GO:0097708	intracellular vesicle

sp|Q99942|RNF5_HUMAN
E3 ubiquitin-protein ligase RNF5
Search

RNF5

0.51	Ring finger protein 5

0.60	GO:0071712	ER-associated misfolded protein catabolic process
0.55	GO:2000785	regulation of autophagosome assembly
0.55	GO:0031648	protein destabilization
0.55	GO:0070534	protein K63-linked ubiquitination
0.54	GO:0070936	protein K48-linked ubiquitination
0.54	GO:0030433	ubiquitin-dependent ERAD pathway
0.51	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.51	GO:0009617	response to bacterium
0.50	GO:0010507	negative regulation of autophagy
0.46	GO:0051865	protein autoubiquitination

0.57	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway
0.56	GO:0044390	ubiquitin-like protein conjugating enzyme binding
0.50	GO:0016874	ligase activity
0.49	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding
0.35	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity

0.63	GO:0036513	Derlin-1 retrotranslocation complex
0.38	GO:0005741	mitochondrial outer membrane
0.37	GO:0044322	endoplasmic reticulum quality control compartment
0.34	GO:0043198	dendritic shaft
0.34	GO:0030426	growth cone
0.34	GO:0001726	ruffle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.50

GO:0016874

sp|Q99943|PLCA_HUMAN
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
Search

AGPAT1

0.51	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

0.67	GO:0008654	phospholipid biosynthetic process
0.55	GO:0046473	phosphatidic acid metabolic process
0.55	GO:0001819	positive regulation of cytokine production
0.53	GO:0045017	glycerolipid biosynthetic process
0.39	GO:0046341	CDP-diacylglycerol metabolic process
0.36	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.34	GO:0031325	positive regulation of cellular metabolic process

0.79	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity
0.33	GO:0005515	protein binding

0.51	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.79

EC:2.3.1.51

GO:0003841

sp|Q99944|EGFL8_HUMAN
Epidermal growth factor-like protein 8
Search

EGFL8

0.92	Palmitoyl-protein thioesterase 2

0.41	GO:0001701	in utero embryonic development
0.38	GO:0098734	macromolecule depalmitoylation
0.38	GO:0030198	extracellular matrix organization
0.38	GO:0010952	positive regulation of peptidase activity
0.37	GO:0007166	cell surface receptor signaling pathway
0.37	GO:0048731	system development
0.37	GO:0030154	cell differentiation
0.36	GO:0071773	cellular response to BMP stimulus
0.35	GO:0060828	regulation of canonical Wnt signaling pathway
0.35	GO:0009653	anatomical structure morphogenesis

0.69	GO:0005509	calcium ion binding
0.38	GO:0098599	palmitoyl hydrolase activity
0.38	GO:0016504	peptidase activator activity
0.35	GO:0005201	extracellular matrix structural constituent
0.34	GO:0016790	thiolester hydrolase activity
0.34	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0008271	secondary active sulfate transmembrane transporter activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0008061	chitin binding
0.33	GO:0008270	zinc ion binding

0.42	GO:0005576	extracellular region
0.33	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.32	GO:0009986	cell surface
0.32	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

0.34

EC:3.1.2

GO:0016790

sp|Q99946|PRRT1_HUMAN
Proline-rich transmembrane protein 1
Search

PRRT1

0.97	LOW QUALITY PROTEIN: proline-rich transmembrane protein 1

0.69	GO:0009607	response to biotic stimulus
0.34	GO:0006099	tricarboxylic acid cycle
0.33	GO:0030218	erythrocyte differentiation
0.32	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0050821	protein stabilization
0.32	GO:0044718	siderophore transmembrane transport
0.32	GO:0006457	protein folding
0.32	GO:0006259	DNA metabolic process
0.32	GO:0006897	endocytosis
0.32	GO:0006974	cellular response to DNA damage stimulus

0.35	GO:0016751	S-succinyltransferase activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0030492	hemoglobin binding
0.32	GO:0016791	phosphatase activity
0.32	GO:0031992	energy transducer activity
0.32	GO:0015343	siderophore transmembrane transporter activity
0.32	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0004527	exonuclease activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.41	GO:0045202	synapse
0.40	GO:0030054	cell junction
0.36	GO:0005886	plasma membrane
0.35	GO:0045252	oxoglutarate dehydrogenase complex
0.32	GO:0009360	DNA polymerase III complex
0.32	GO:0030288	outer membrane-bounded periplasmic space
0.30	GO:0016021	integral component of membrane

0.35

GO:0016751

sp|Q99952|PTN18_HUMAN
Tyrosine-protein phosphatase non-receptor type 18
Search

PTPN18

0.58	Tyrosine-protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.50	GO:0035644	phosphoanandamide dephosphorylation
0.49	GO:1902523	positive regulation of protein K63-linked ubiquitination
0.49	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation
0.49	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
0.49	GO:0071663	positive regulation of granzyme B production
0.49	GO:0034157	positive regulation of toll-like receptor 7 signaling pathway
0.48	GO:1903753	negative regulation of p38MAPK cascade
0.48	GO:0071225	cellular response to muramyl dipeptide
0.48	GO:2000483	negative regulation of interleukin-8 secretion

0.74	GO:0004725	protein tyrosine phosphatase activity
0.45	GO:0017124	SH3 domain binding
0.44	GO:0019900	kinase binding
0.41	GO:0008092	cytoskeletal protein binding
0.39	GO:0017080	sodium channel regulator activity
0.39	GO:0001784	phosphotyrosine residue binding
0.39	GO:0051117	ATPase binding
0.36	GO:0031625	ubiquitin protein ligase binding

0.48	GO:0005634	nucleus
0.45	GO:0009898	cytoplasmic side of plasma membrane
0.42	GO:0005737	cytoplasm
0.41	GO:0005856	cytoskeleton
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.74

GO:0004725

sp|Q99954|SMR3A_HUMAN
Submaxillary gland androgen-regulated protein 3A
Search

SMR3A

0.76	Submaxillary gland androgen regulated protein 3 homolog A (Mouse)

0.44	GO:0006338	chromatin remodeling
0.43	GO:0009664	plant-type cell wall organization
0.40	GO:0032509	endosome transport via multivesicular body sorting pathway
0.38	GO:0009992	cellular water homeostasis
0.38	GO:0051930	regulation of sensory perception of pain
0.38	GO:0015031	protein transport
0.38	GO:0035176	social behavior
0.37	GO:0009651	response to salt stress
0.37	GO:0007599	hemostasis
0.37	GO:0065009	regulation of molecular function

0.43	GO:0005199	structural constituent of cell wall
0.41	GO:0005544	calcium-dependent phospholipid binding
0.41	GO:0048306	calcium-dependent protein binding
0.40	GO:0005509	calcium ion binding
0.39	GO:0003676	nucleic acid binding
0.38	GO:0098772	molecular function regulator
0.38	GO:0005178	integrin binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.37	GO:0017048	Rho GTPase binding

0.44	GO:0005576	extracellular region
0.43	GO:0070603	SWI/SNF superfamily-type complex
0.42	GO:0031982	vesicle
0.40	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0012505	endomembrane system
0.36	GO:0098796	membrane protein complex
0.36	GO:0044444	cytoplasmic part
0.35	GO:0031984	organelle subcompartment
0.34	GO:0031967	organelle envelope

0.37

GO:0004674

sp|Q99956|DUS9_HUMAN
Dual specificity protein phosphatase 9
Search

0.71	Dual specificity protein phosphatase

0.84	GO:0000188	inactivation of MAPK activity
0.71	GO:0006470	protein dephosphorylation
0.41	GO:0042663	regulation of endodermal cell fate specification
0.40	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.40	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.40	GO:0009953	dorsal/ventral pattern formation
0.37	GO:0000187	activation of MAPK activity
0.37	GO:0000165	MAPK cascade
0.36	GO:0060420	regulation of heart growth
0.36	GO:0031098	stress-activated protein kinase signaling cascade

0.84	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.70	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0005515	protein binding
0.33	GO:0016301	kinase activity
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0005840	ribosome
0.32	GO:0044446	intracellular organelle part

0.84

GO:0017017

sp|Q99958|FOXC2_HUMAN
Forkhead box protein C2
Search

FOXC2

0.96	Forkhead box protein C1-B

0.66	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis
0.63	GO:0072010	glomerular epithelium development
0.63	GO:0048341	paraxial mesoderm formation
0.63	GO:0014032	neural crest cell development
0.62	GO:0060038	cardiac muscle cell proliferation
0.62	GO:0035470	positive regulation of vascular wound healing
0.62	GO:0001945	lymph vessel development
0.62	GO:0001756	somitogenesis
0.61	GO:0072144	glomerular mesangial cell development
0.61	GO:0001974	blood vessel remodeling

0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:1990841	promoter-specific chromatin binding
0.60	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.57	GO:0031490	chromatin DNA binding
0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0042802	identical protein binding
0.44	GO:0001223	transcription coactivator binding
0.42	GO:0008301	DNA binding, bending
0.41	GO:0003713	transcription coactivator activity

0.59	GO:0005634	nucleus
0.50	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol
0.38	GO:0005694	chromosome

sp|Q99959|PKP2_HUMAN
Plakophilin-2
Search

PKP2

0.84	Truncated plakophilin-2

0.77	GO:0098609	cell-cell adhesion
0.63	GO:0045110	intermediate filament bundle assembly
0.62	GO:0048496	maintenance of animal organ identity
0.62	GO:0002934	desmosome organization
0.62	GO:0086069	bundle of His cell to Purkinje myocyte communication
0.61	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.61	GO:0086005	ventricular cardiac muscle cell action potential
0.61	GO:0086019	cell-cell signaling involved in cardiac conduction
0.60	GO:0086091	regulation of heart rate by cardiac conduction
0.60	GO:0055010	ventricular cardiac muscle tissue morphogenesis

0.61	GO:0045294	alpha-catenin binding
0.61	GO:0019215	intermediate filament binding
0.60	GO:0005080	protein kinase C binding
0.57	GO:0045296	cadherin binding
0.57	GO:0032947	protein complex scaffold activity
0.40	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
0.39	GO:0017080	sodium channel regulator activity
0.39	GO:0044325	ion channel binding
0.35	GO:0071253	connexin binding
0.34	GO:0005521	lamin binding

0.59	GO:0014704	intercalated disc
0.54	GO:0030057	desmosome
0.51	GO:0005654	nucleoplasm
0.49	GO:0005912	adherens junction
0.48	GO:0005882	intermediate filament
0.43	GO:0005886	plasma membrane
0.40	GO:1990124	messenger ribonucleoprotein complex
0.32	GO:0005731	nucleolus organizer region
0.32	GO:0005874	microtubule
0.32	GO:0005871	kinesin complex

0.32

GO:0016787

sp|Q99961|SH3G1_HUMAN
Endophilin-A2
Search

SH3GL1

0.95	Kinase C and casein kinase II substrate protein 3

0.71	GO:0006897	endocytosis
0.61	GO:0072318	clathrin coat disassembly
0.58	GO:0036465	synaptic vesicle recycling
0.56	GO:0099003	vesicle-mediated transport in synapse
0.47	GO:0030100	regulation of endocytosis
0.47	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.46	GO:0097484	dendrite extension
0.41	GO:1903421	regulation of synaptic vesicle recycling
0.41	GO:0098815	modulation of excitatory postsynaptic potential
0.39	GO:0099050	vesicle scission

0.54	GO:0045296	cadherin binding
0.53	GO:0042802	identical protein binding
0.42	GO:0031697	beta-1 adrenergic receptor binding
0.42	GO:0008022	protein C-terminus binding
0.40	GO:0044325	ion channel binding
0.40	GO:0019902	phosphatase binding
0.39	GO:0008289	lipid binding
0.39	GO:0017124	SH3 domain binding
0.38	GO:0051020	GTPase binding
0.36	GO:0019901	protein kinase binding

0.53	GO:0045202	synapse
0.49	GO:0005737	cytoplasm
0.44	GO:0097708	intracellular vesicle
0.42	GO:0012505	endomembrane system
0.41	GO:0002102	podosome
0.38	GO:0030054	cell junction
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0042995	cell projection
0.35	GO:0070062	extracellular exosome

sp|Q99962|SH3G2_HUMAN
Endophilin-A1
Search

SH3GL2

0.97	Endophilin-1

0.71	GO:0006897	endocytosis
0.60	GO:0072318	clathrin coat disassembly
0.58	GO:0036465	synaptic vesicle recycling
0.57	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.56	GO:0097484	dendrite extension
0.56	GO:0099003	vesicle-mediated transport in synapse
0.55	GO:0002090	regulation of receptor internalization
0.40	GO:0099050	vesicle scission
0.40	GO:1900242	regulation of synaptic vesicle endocytosis
0.39	GO:0097753	membrane bending

0.52	GO:0042802	identical protein binding
0.44	GO:0045296	cadherin binding
0.41	GO:0008022	protein C-terminus binding
0.40	GO:0031697	beta-1 adrenergic receptor binding
0.40	GO:0008289	lipid binding
0.39	GO:0019899	enzyme binding
0.39	GO:0044325	ion channel binding
0.38	GO:0017124	SH3 domain binding

0.53	GO:0005769	early endosome
0.52	GO:0045202	synapse
0.41	GO:0005829	cytosol
0.39	GO:0002102	podosome
0.38	GO:0044433	cytoplasmic vesicle part
0.38	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0030054	cell junction
0.36	GO:0042995	cell projection
0.36	GO:0070062	extracellular exosome

sp|Q99963|SH3G3_HUMAN
Endophilin-A3
Search

SH3GL3

0.97	SH3 domain containing GRB2 like 3, endophilin A3

0.71	GO:0006897	endocytosis
0.44	GO:0072318	clathrin coat disassembly
0.43	GO:0036465	synaptic vesicle recycling
0.42	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.42	GO:0099003	vesicle-mediated transport in synapse
0.42	GO:0097484	dendrite extension
0.41	GO:0002090	regulation of receptor internalization
0.37	GO:0099050	vesicle scission
0.37	GO:0097753	membrane bending
0.37	GO:0097749	membrane tubulation

0.50	GO:0042802	identical protein binding
0.39	GO:0008022	protein C-terminus binding
0.39	GO:0008289	lipid binding
0.35	GO:0019901	protein kinase binding
0.33	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0045296	cadherin binding

0.49	GO:0005737	cytoplasm
0.41	GO:0097708	intracellular vesicle
0.40	GO:0045202	synapse
0.40	GO:0012505	endomembrane system
0.38	GO:0070062	extracellular exosome
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.35	GO:0044446	intracellular organelle part
0.34	GO:0012506	vesicle membrane
0.33	GO:0005886	plasma membrane

sp|Q99965|ADAM2_HUMAN
Disintegrin and metalloproteinase domain-containing protein 2
Search

0.94	Disintegrin and metalloproteinase domain-containing protein 2

0.64	GO:0007338	single fertilization
0.61	GO:0006508	proteolysis
0.57	GO:0007229	integrin-mediated signaling pathway
0.46	GO:0008542	visual learning
0.45	GO:0007155	cell adhesion
0.45	GO:0030534	adult behavior
0.42	GO:0010604	positive regulation of macromolecule metabolic process
0.38	GO:0032504	multicellular organism reproduction
0.38	GO:0010468	regulation of gene expression
0.37	GO:0034241	positive regulation of macrophage fusion

0.70	GO:0004222	metalloendopeptidase activity
0.41	GO:0046872	metal ion binding
0.40	GO:0005178	integrin binding
0.36	GO:0043236	laminin binding
0.36	GO:0005518	collagen binding
0.36	GO:0017124	SH3 domain binding
0.33	GO:0020037	heme binding
0.32	GO:0004984	olfactory receptor activity

0.43	GO:0009986	cell surface
0.38	GO:0043234	protein complex
0.35	GO:0001669	acrosomal vesicle
0.35	GO:0005887	integral component of plasma membrane

0.70

GO:0004222

sp|Q99966|CITE1_HUMAN
Cbp/p300-interacting transactivator 1
Search

CITED1

0.97	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1

0.63	GO:0071104	response to interleukin-9
0.63	GO:0071105	response to interleukin-11
0.61	GO:0001570	vasculogenesis
0.61	GO:0070669	response to interleukin-2
0.61	GO:0071107	response to parathyroid hormone
0.61	GO:0060712	spongiotrophoblast layer development
0.60	GO:0030318	melanocyte differentiation
0.60	GO:0070741	response to interleukin-6
0.60	GO:0070670	response to interleukin-4
0.59	GO:0045668	negative regulation of osteoblast differentiation

0.62	GO:0050693	LBD domain binding
0.60	GO:0070410	co-SMAD binding
0.59	GO:0003713	transcription coactivator activity
0.57	GO:0003682	chromatin binding
0.56	GO:0008022	protein C-terminus binding
0.54	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0001104	RNA polymerase II transcription cofactor activity
0.44	GO:0001102	RNA polymerase II activating transcription factor binding

0.61	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.40	GO:0000785	chromatin
0.39	GO:0043233	organelle lumen
0.33	GO:0032991	macromolecular complex

0.36

EC:3.5.1.98

GO:0032041

sp|Q99967|CITE2_HUMAN
Cbp/p300-interacting transactivator 2
Search

CITED2

0.96	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

0.65	GO:0035801	adrenal cortex development
0.64	GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry
0.63	GO:2000020	positive regulation of male gonad development
0.63	GO:0060971	embryonic heart tube left/right pattern formation
0.61	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.61	GO:0070986	left/right axis specification
0.61	GO:0061156	pulmonary artery morphogenesis
0.61	GO:0061308	cardiac neural crest cell development involved in heart development
0.61	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.61	GO:0001570	vasculogenesis

0.63	GO:0001105	RNA polymerase II transcription coactivator activity
0.60	GO:0046332	SMAD binding
0.58	GO:0001102	RNA polymerase II activating transcription factor binding
0.57	GO:0003682	chromatin binding
0.50	GO:0050693	LBD domain binding
0.47	GO:0003700	DNA binding transcription factor activity
0.44	GO:0003714	transcription corepressor activity
0.43	GO:0035035	histone acetyltransferase binding
0.42	GO:0008022	protein C-terminus binding
0.42	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.52	GO:0000785	chromatin
0.49	GO:0043233	organelle lumen
0.39	GO:0005829	cytosol
0.37	GO:0043234	protein complex

0.33

EC:3.5.1.98

GO:0032041

sp|Q99969|RARR2_HUMAN
Retinoic acid receptor responder protein 2
Search

RARRES2

0.97	Retinoic acid receptor responder protein 2

0.85	GO:0050994	regulation of lipid catabolic process
0.80	GO:0006954	inflammatory response
0.77	GO:0061760	antifungal innate immune response
0.74	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.74	GO:0010759	positive regulation of macrophage chemotaxis
0.73	GO:0019732	antifungal humoral response
0.71	GO:0048566	embryonic digestive tract development
0.70	GO:0001523	retinoid metabolic process
0.70	GO:0050830	defense response to Gram-positive bacterium
0.69	GO:0050829	defense response to Gram-negative bacterium

0.72

GO:0005102

receptor binding

0.62	GO:0031012	extracellular matrix
0.61	GO:0005615	extracellular space
0.41	GO:0031089	platelet dense granule lumen
0.41	GO:1903561	extracellular vesicle

sp|Q99972|MYOC_HUMAN
Myocilin
Search

MYOC

0.97	Myocilin, trabecular meshwork-inducible glucocorticoid response

0.78	GO:0051492	regulation of stress fiber assembly
0.78	GO:0001952	regulation of cell-matrix adhesion
0.74	GO:0030335	positive regulation of cell migration
0.62	GO:0038133	ERBB2-ERBB3 signaling pathway
0.62	GO:0014734	skeletal muscle hypertrophy
0.60	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade
0.60	GO:0007399	nervous system development
0.59	GO:0051901	positive regulation of mitochondrial depolarization
0.58	GO:0032232	negative regulation of actin filament bundle assembly
0.58	GO:1903393	positive regulation of adherens junction organization

0.58	GO:0032027	myosin light chain binding
0.57	GO:0001968	fibronectin binding
0.56	GO:0005109	frizzled binding
0.56	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0046872	metal ion binding
0.34	GO:0001540	amyloid-beta binding
0.32	GO:0045296	cadherin binding
0.32	GO:0042803	protein homodimerization activity

0.68	GO:0005615	extracellular space
0.59	GO:0033268	node of Ranvier
0.53	GO:0005758	mitochondrial intermembrane space
0.53	GO:0005741	mitochondrial outer membrane
0.51	GO:0031012	extracellular matrix
0.50	GO:0031410	cytoplasmic vesicle
0.50	GO:0005794	Golgi apparatus
0.50	GO:0005783	endoplasmic reticulum
0.45	GO:0005743	mitochondrial inner membrane
0.43	GO:1903561	extracellular vesicle

sp|Q99973|TEP1_HUMAN
Telomerase protein component 1
Search

TEP1

0.80	Telomerase associated protein 1

0.45	GO:0000722	telomere maintenance via recombination
0.41	GO:0008380	RNA splicing
0.41	GO:0006278	RNA-dependent DNA biosynthetic process
0.35	GO:0010833	telomere maintenance via telomere lengthening
0.35	GO:0042157	lipoprotein metabolic process
0.35	GO:0006869	lipid transport

0.57	GO:0003723	RNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003720	telomerase activity
0.45	GO:0002039	p53 binding
0.41	GO:0019899	enzyme binding
0.35	GO:0008289	lipid binding

0.46	GO:0005697	telomerase holoenzyme complex
0.45	GO:0016363	nuclear matrix
0.44	GO:0071011	precatalytic spliceosome
0.44	GO:0005682	U5 snRNP
0.43	GO:0071013	catalytic step 2 spliceosome
0.35	GO:0005737	cytoplasm
0.34	GO:0000781	chromosome, telomeric region
0.34	GO:0005576	extracellular region

0.45

GO:0003720

sp|Q99983|OMD_HUMAN
Osteomodulin
Search

OMD

0.97	Osteomodulin

0.85	GO:0030500	regulation of bone mineralization
0.54	GO:0007409	axonogenesis
0.42	GO:0007155	cell adhesion
0.41	GO:0042340	keratan sulfate catabolic process
0.40	GO:0018146	keratan sulfate biosynthetic process

0.74	GO:0031012	extracellular matrix
0.51	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.40	GO:0043202	lysosomal lumen
0.39	GO:0005796	Golgi lumen

sp|Q99985|SEM3C_HUMAN
Semaphorin-3C
Search

SEMA3C

0.97	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

0.85	GO:0140074	cardiac endothelial to mesenchymal transition
0.84	GO:0003350	pulmonary myocardium development
0.83	GO:1905312	positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
0.83	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching
0.81	GO:0060174	limb bud formation
0.80	GO:0003215	cardiac right ventricle morphogenesis
0.79	GO:0003148	outflow tract septum morphogenesis
0.79	GO:0001974	blood vessel remodeling
0.78	GO:0001755	neural crest cell migration
0.77	GO:0001756	somitogenesis

0.81	GO:0030215	semaphorin receptor binding
0.66	GO:0038191	neuropilin binding
0.37	GO:0045499	chemorepellent activity
0.34	GO:0003735	structural constituent of ribosome

0.68	GO:0005615	extracellular space
0.44	GO:1903561	extracellular vesicle
0.34	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|Q99986|VRK1_HUMAN
Serine/threonine-protein kinase VRK1
Search

VRK1

0.92	Serine/threonine-protein kinase VRK1

0.63	GO:0006468	protein phosphorylation
0.47	GO:0090166	Golgi disassembly
0.44	GO:0018209	peptidyl-serine modification
0.42	GO:0018210	peptidyl-threonine modification
0.40	GO:0016570	histone modification
0.40	GO:0008360	regulation of cell shape
0.39	GO:0051301	cell division
0.39	GO:0007049	cell cycle
0.38	GO:0051081	nuclear envelope disassembly
0.38	GO:0031468	nuclear envelope reassembly

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031493	nucleosomal histone binding
0.43	GO:0035173	histone kinase activity
0.41	GO:0019901	protein kinase binding

0.43	GO:0005795	Golgi stack
0.40	GO:0005819	spindle
0.39	GO:0005730	nucleolus
0.39	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

sp|Q99988|GDF15_HUMAN
Growth/differentiation factor 15
Search

GDF15

0.97	Growth differentiation factor 15

0.76	GO:0010469	regulation of receptor activity
0.69	GO:0060395	SMAD protein signal transduction
0.69	GO:1901741	positive regulation of myoblast fusion
0.55	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.54	GO:0030509	BMP signaling pathway
0.51	GO:0043408	regulation of MAPK cascade
0.50	GO:0048468	cell development
0.50	GO:0042981	regulation of apoptotic process
0.41	GO:0007179	transforming growth factor beta receptor signaling pathway
0.38	GO:0007267	cell-cell signaling

0.78	GO:0008083	growth factor activity
0.55	GO:0005160	transforming growth factor beta receptor binding
0.52	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.57	GO:0005794	Golgi apparatus
0.51	GO:0005634	nucleus
0.40	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

sp|Q99990|VGLL1_HUMAN
Transcription cofactor vestigial-like protein 1
Search

VGLL1

0.94	Transcription cofactor vestigial-like protein 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:0007519	skeletal muscle tissue development
0.39	GO:0048703	embryonic viscerocranium morphogenesis
0.39	GO:0014032	neural crest cell development
0.35	GO:0006351	transcription, DNA-templated

0.56	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0003713	transcription coactivator activity
0.45	GO:0008022	protein C-terminus binding

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q99996|AKAP9_HUMAN
A-kinase anchor protein 9
Search

AKAP9

0.74	A-kinase anchoring protein 9

0.60	GO:0007165	signal transduction
0.59	GO:0051661	maintenance of centrosome location
0.59	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction
0.59	GO:1903358	regulation of Golgi organization
0.58	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.57	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.57	GO:0086091	regulation of heart rate by cardiac conduction
0.57	GO:0071320	cellular response to cAMP
0.56	GO:0031116	positive regulation of microtubule polymerization
0.56	GO:0033138	positive regulation of peptidyl-serine phosphorylation

0.81	GO:0032947	protein complex scaffold activity
0.57	GO:0015459	potassium channel regulator activity
0.57	GO:0034237	protein kinase A regulatory subunit binding
0.56	GO:0044325	ion channel binding
0.50	GO:0003677	DNA binding
0.47	GO:0016301	kinase activity
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0005102	receptor binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein

0.54	GO:0005801	cis-Golgi network
0.54	GO:0005813	centrosome
0.54	GO:0005795	Golgi stack
0.52	GO:0008076	voltage-gated potassium channel complex
0.44	GO:0044307	dendritic branch
0.41	GO:0043025	neuronal cell body
0.40	GO:0097060	synaptic membrane
0.38	GO:0036064	ciliary basal body
0.38	GO:0044450	microtubule organizing center part
0.36	GO:0005829	cytosol

0.33

GO:0016773

sp|Q99999|G3ST1_HUMAN
Galactosylceramide sulfotransferase
Search

GAL3ST1

0.96	Galactosylceramide sulfotransferase

0.73	GO:0009247	glycolipid biosynthetic process
0.55	GO:0006681	galactosylceramide metabolic process
0.54	GO:0046513	ceramide biosynthetic process
0.53	GO:0042552	myelination
0.52	GO:0007283	spermatogenesis
0.35	GO:0006487	protein N-linked glycosylation
0.33	GO:0006364	rRNA processing

0.85

GO:0050694

galactose 3-O-sulfotransferase activity

0.72	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005730	nucleolus
0.34	GO:0005654	nucleoplasm

0.85

GO:0050694

sp|Q9BPU6|DPYL5_HUMAN
Dihydropyrimidinase-related protein 5
Search

DPYSL5

0.92	Dihydropyrimidinase like 5

0.69	GO:0007411	axon guidance
0.42	GO:0006212	uracil catabolic process
0.40	GO:0006210	thymine catabolic process
0.40	GO:0019482	beta-alanine metabolic process
0.39	GO:0051289	protein homotetramerization

0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.64	GO:0008017	microtubule binding
0.42	GO:0051219	phosphoprotein binding
0.41	GO:0002059	thymine binding
0.41	GO:0002058	uracil binding
0.37	GO:0016597	amino acid binding
0.35	GO:0008270	zinc ion binding

0.65	GO:0043025	neuronal cell body
0.65	GO:0030425	dendrite
0.49	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome

0.65

EC:3.5

GO:0016810

sp|Q9BPU9|B9D2_HUMAN
B9 domain-containing protein 2
Search

B9D2

0.93	Transforming growth factor beta 1

0.75	GO:0060271	cilium assembly
0.60	GO:0036372	opsin transport
0.56	GO:0001736	establishment of planar polarity
0.53	GO:0007163	establishment or maintenance of cell polarity
0.45	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.45	GO:1901664	regulation of NAD+ ADP-ribosyltransferase activity
0.45	GO:0043932	ossification involved in bone remodeling
0.44	GO:0048298	positive regulation of isotype switching to IgA isotypes
0.44	GO:0007182	common-partner SMAD protein phosphorylation
0.44	GO:0010936	negative regulation of macrophage cytokine production

0.72	GO:0043015	gamma-tubulin binding
0.45	GO:0034714	type III transforming growth factor beta receptor binding
0.44	GO:0005114	type II transforming growth factor beta receptor binding
0.44	GO:0034713	type I transforming growth factor beta receptor binding
0.43	GO:0003823	antigen binding
0.42	GO:0008083	growth factor activity
0.34	GO:0004190	aspartic-type endopeptidase activity

0.76	GO:0036038	MKS complex
0.74	GO:0036064	ciliary basal body
0.69	GO:0005813	centrosome
0.43	GO:0072562	blood microparticle
0.42	GO:0005634	nucleus
0.41	GO:0009986	cell surface
0.38	GO:0005737	cytoplasm
0.37	GO:0044292	dendrite terminus
0.30	GO:0016020	membrane

0.34

EC:3.4.23

GO:0004190

sp|Q9BPV8|P2Y13_HUMAN
P2Y purinoceptor 13
Search

P2RY13

0.92	Purinergic receptor P2Y G-protein coupled 13

0.85	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.77	GO:0007194	negative regulation of adenylate cyclase activity
0.53	GO:0071407	cellular response to organic cyclic compound
0.53	GO:0007596	blood coagulation
0.44	GO:0001775	cell activation
0.42	GO:1904139	regulation of microglial cell migration
0.42	GO:0006930	substrate-dependent cell migration, cell extension
0.41	GO:0034109	homotypic cell-cell adhesion
0.41	GO:0001973	adenosine receptor signaling pathway
0.41	GO:0033198	response to ATP

0.85	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.41	GO:0001609	G-protein coupled adenosine receptor activity
0.33	GO:0045125	bioactive lipid receptor activity
0.32	GO:0048020	CCR chemokine receptor binding
0.32	GO:0004950	chemokine receptor activity

0.48	GO:0005783	endoplasmic reticulum
0.45	GO:0005887	integral component of plasma membrane

sp|Q9BPW4|APOL4_HUMAN
Apolipoprotein L4
Search

0.86	Apolipoprotein L4

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.38	GO:0006954	inflammatory response
0.37	GO:0008203	cholesterol metabolic process
0.37	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.36	GO:0060135	maternal process involved in female pregnancy
0.35	GO:0043687	post-translational protein modification
0.35	GO:0031640	killing of cells of other organism
0.35	GO:0045087	innate immune response
0.34	GO:0019835	cytolysis

0.72	GO:0008289	lipid binding
0.36	GO:0008035	high-density lipoprotein particle binding
0.36	GO:0005319	lipid transporter activity
0.35	GO:0005515	protein binding
0.34	GO:0004871	signal transducer activity
0.34	GO:0005254	chloride channel activity

0.66	GO:0005576	extracellular region
0.38	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0012505	endomembrane system
0.35	GO:1990777	lipoprotein particle
0.34	GO:0031984	organelle subcompartment
0.34	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

sp|Q9BPW5|RSLBB_HUMAN
Ras-like protein family member 11B
Search

RASL11B

0.97	RAS like family 11 member B

0.61	GO:0007165	signal transduction
0.56	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.45	GO:0045943	positive regulation of transcription by RNA polymerase I
0.43	GO:0048382	mesendoderm development
0.32	GO:0006351	transcription, DNA-templated

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.57	GO:0005160	transforming growth factor beta receptor binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|Q9BPW8|NIPS1_HUMAN
Protein NipSnap homolog 1
Search

NIPSNAP1

0.94	LOW QUALITY PROTEIN: protein NipSnap homolog 1

0.76	GO:0019233	sensory perception of pain
0.63	GO:2000984	negative regulation of ATP citrate synthase activity
0.50	GO:0006754	ATP biosynthetic process
0.47	GO:0006119	oxidative phosphorylation

0.72	GO:0042165	neurotransmitter binding
0.38	GO:0005515	protein binding

0.69	GO:0097060	synaptic membrane
0.60	GO:0005739	mitochondrion
0.60	GO:0031967	organelle envelope
0.59	GO:0031090	organelle membrane
0.51	GO:0098805	whole membrane
0.48	GO:0019867	outer membrane

sp|Q9BPW9|DHRS9_HUMAN
Dehydrogenase/reductase SDR family member 9
Search

DHRS9

0.97	Retinol dehydrogenase homolog

0.65	GO:0042904	9-cis-retinoic acid biosynthetic process
0.63	GO:0008209	androgen metabolic process
0.63	GO:0042448	progesterone metabolic process
0.50	GO:0055114	oxidation-reduction process
0.41	GO:0042572	retinol metabolic process
0.40	GO:0035138	pectoral fin morphogenesis
0.40	GO:0042574	retinal metabolic process
0.40	GO:0031017	exocrine pancreas development
0.39	GO:0060429	epithelium development
0.38	GO:0031018	endocrine pancreas development

0.68	GO:0004745	retinol dehydrogenase activity
0.65	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.58	GO:0004022	alcohol dehydrogenase (NAD) activity
0.36	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.35	GO:0016854	racemase and epimerase activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0003723	RNA binding

0.56	GO:0030176	integral component of endoplasmic reticulum membrane
0.39	GO:0005730	nucleolus
0.38	GO:0005829	cytosol
0.37	GO:0031090	organelle membrane
0.34	GO:0005769	early endosome
0.34	GO:0044440	endosomal part
0.33	GO:0098805	whole membrane

0.68	EC:1.1.1.105	GO:0004745
0.65	KEGG:R01836	GO:0047035

sp|Q9BPX1|DHB14_HUMAN
17-beta-hydroxysteroid dehydrogenase 14
Search

HSD17B14

0.42	Branched chain amino acid transaminase 2

0.55	GO:0006706	steroid catabolic process
0.50	GO:0055114	oxidation-reduction process
0.39	GO:0032259	methylation
0.37	GO:0009081	branched-chain amino acid metabolic process
0.37	GO:0006703	estrogen biosynthetic process
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0046394	carboxylic acid biosynthetic process

0.57	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity
0.55	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.49	GO:0042802	identical protein binding
0.42	GO:0008171	O-methyltransferase activity
0.39	GO:0004084	branched-chain-amino-acid transaminase activity
0.35	GO:0003735	structural constituent of ribosome
0.35	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.33	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.33	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.33	GO:0051287	NAD binding

0.47	GO:0005829	cytosol
0.35	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.57	EC:1.1.1.64	GO:0047045
0.57	KEGG:R01838	GO:0047045

sp|Q9BPX3|CND3_HUMAN
Condensin complex subunit 3
Search

NCAPG

0.90	Non-SMC condensin I complex subunit G

0.81	GO:0007076	mitotic chromosome condensation
0.35	GO:0051301	cell division

0.34

GO:0005515

protein binding

0.82	GO:0000796	condensin complex
0.57	GO:0000779	condensed chromosome, centromeric region
0.41	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BPX5|ARP5L_HUMAN
Actin-related protein 2/3 complex subunit 5-like protein
Search

ARPC5L

0.71	Actin-related protein 2/3 complex subunit 5

0.80	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.51	GO:0016477	cell migration
0.35	GO:0021769	orbitofrontal cortex development
0.35	GO:0051639	actin filament network formation
0.34	GO:0030011	maintenance of cell polarity
0.34	GO:0097581	lamellipodium organization
0.34	GO:0061842	microtubule organizing center localization

0.51	GO:0051015	actin filament binding
0.44	GO:0005200	structural constituent of cytoskeleton

0.80	GO:0005885	Arp2/3 protein complex
0.46	GO:0030027	lamellipodium
0.37	GO:0005737	cytoplasm
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0030426	growth cone
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system

sp|Q9BPX6|MICU1_HUMAN
Calcium uptake protein 1, mitochondrial
Search

MICU1

0.94	Mitochondrial calcium uptake 1

0.57	GO:0051561	positive regulation of mitochondrial calcium ion concentration
0.56	GO:0006851	mitochondrial calcium ion transmembrane transport
0.55	GO:0070509	calcium ion import
0.53	GO:0060401	cytosolic calcium ion transport
0.50	GO:0051260	protein homooligomerization
0.34	GO:0006952	defense response

0.70	GO:0005509	calcium ion binding
0.49	GO:0046982	protein heterodimerization activity
0.48	GO:0042802	identical protein binding

0.56	GO:1990246	uniplex complex
0.52	GO:0032592	integral component of mitochondrial membrane
0.52	GO:0005758	mitochondrial intermembrane space

sp|Q9BPX7|CG025_HUMAN
UPF0415 protein C7orf25
Search

0.28	Proteasome endopeptidase complex

0.60	GO:0051603	proteolysis involved in cellular protein catabolic process
0.47	GO:0043632	modification-dependent macromolecule catabolic process

0.64	GO:0070003	threonine-type peptidase activity
0.55	GO:0004175	endopeptidase activity
0.44	GO:0005515	protein binding

0.63	GO:0005839	proteasome core complex
0.43	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm

sp|Q9BPY3|F118B_HUMAN
Protein FAM118B
Search

0.85	GO:0030576	Cajal body organization
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.40	GO:0015030	Cajal body
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

sp|Q9BPY8|HOP_HUMAN
Homeodomain-only protein
Search

HOPX

0.97	Homeodomain-only protein (Fragment)

0.62	GO:0043415	positive regulation of skeletal muscle tissue regeneration
0.60	GO:0048286	lung alveolus development
0.59	GO:0051155	positive regulation of striated muscle cell differentiation
0.57	GO:0008016	regulation of heart contraction
0.57	GO:0043393	regulation of protein binding
0.56	GO:0016575	histone deacetylation
0.56	GO:0007507	heart development
0.55	GO:0001829	trophectodermal cell differentiation
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0051131	chaperone-mediated protein complex assembly

0.55	GO:0003677	DNA binding
0.36	GO:0005515	protein binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q9BPZ2|SPI2B_HUMAN
Spindlin-2B
Search

SPIN1

0.95	Z-linked spindlin 1

0.78	GO:0007276	gamete generation
0.56	GO:0051726	regulation of cell cycle
0.47	GO:0009303	rRNA transcription
0.46	GO:0030177	positive regulation of Wnt signaling pathway
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0007049	cell cycle
0.37	GO:0016055	Wnt signaling pathway
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0007275	multicellular organism development
0.36	GO:0006915	apoptotic process

0.49	GO:0140034	methylation-dependent protein binding
0.48	GO:0042393	histone binding
0.34	GO:0018738	S-formylglutathione hydrolase activity
0.33	GO:0003677	DNA binding
0.33	GO:0052689	carboxylic ester hydrolase activity

0.52	GO:0005634	nucleus
0.44	GO:0005819	spindle
0.44	GO:0005829	cytosol
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0012505	endomembrane system
0.40	GO:0031967	organelle envelope
0.39	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:3.1.2.12	GO:0018738
0.34	KEGG:R00527	GO:0018738

sp|Q9BPZ3|PAIP2_HUMAN
Polyadenylate-binding protein-interacting protein 2
Search

PAIP2

0.97	Polyadenylate-binding protein-interacting protein 2

0.83	GO:1900271	regulation of long-term synaptic potentiation
0.79	GO:0045947	negative regulation of translational initiation
0.78	GO:0007613	memory
0.74	GO:0007283	spermatogenesis

0.84	GO:0030371	translation repressor activity
0.70	GO:0003729	mRNA binding
0.51	GO:0090079	translation regulator activity, nucleic acid binding
0.42	GO:0008143	poly(A) binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0005515	protein binding

0.47	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus

sp|Q9BPZ7|SIN1_HUMAN
Target of rapamycin complex 2 subunit MAPKAP1
Search

MAPKAP1

0.95	Mitogen-activated protein kinase associated protein 1

0.57	GO:0046580	negative regulation of Ras protein signal transduction
0.50	GO:0038203	TORC2 signaling
0.50	GO:0030950	establishment or maintenance of actin cytoskeleton polarity
0.49	GO:0090133	mesendoderm migration
0.49	GO:0031098	stress-activated protein kinase signaling cascade
0.47	GO:0042074	cell migration involved in gastrulation
0.45	GO:0060491	regulation of cell projection assembly
0.40	GO:0016310	phosphorylation
0.39	GO:0021762	substantia nigra development
0.36	GO:0032148	activation of protein kinase B activity

0.60	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.60	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.60	GO:0070300	phosphatidic acid binding
0.59	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.58	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0017016	Ras GTPase binding
0.41	GO:0016301	kinase activity

0.82	GO:0031932	TORC2 complex
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.40	GO:0031410	cytoplasmic vesicle

sp|Q9BQ04|RBM4B_HUMAN
RNA-binding protein 4B
Search

0.96	RNA binding motif protein 4

0.58	GO:0043153	entrainment of circadian clock by photoperiod
0.55	GO:0032922	circadian regulation of gene expression
0.54	GO:0006417	regulation of translation
0.53	GO:0002192	IRES-dependent translational initiation of linear mRNA
0.52	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.52	GO:0048518	positive regulation of biological process
0.51	GO:0046822	regulation of nucleocytoplasmic transport
0.50	GO:0051147	regulation of muscle cell differentiation
0.50	GO:0035194	posttranscriptional gene silencing by RNA
0.49	GO:0046685	response to arsenic-containing substance

0.60	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.49	GO:0030332	cyclin binding

0.52	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.49	GO:0010494	cytoplasmic stress granule
0.49	GO:0005730	nucleolus
0.42	GO:0043234	protein complex
0.40	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

sp|Q9BQ08|RETNB_HUMAN
Resistin-like beta
Search

RETN

0.97	Hypoxia-induced mitogenic factor

0.76	GO:0010469	regulation of receptor activity
0.42	GO:2000872	positive regulation of progesterone secretion
0.41	GO:2000252	negative regulation of feeding behavior
0.40	GO:0050806	positive regulation of synaptic transmission
0.40	GO:0045444	fat cell differentiation
0.39	GO:0032868	response to insulin
0.39	GO:0009612	response to mechanical stimulus
0.39	GO:0007568	aging
0.39	GO:0043312	neutrophil degranulation
0.38	GO:0008283	cell proliferation

0.79	GO:0005179	hormone activity
0.37	GO:0030348	syntaxin-3 binding
0.36	GO:0017075	syntaxin-1 binding
0.36	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.39	GO:0005766	primary lysosome
0.39	GO:0042581	specific granule
0.37	GO:0044433	cytoplasmic vesicle part
0.37	GO:0044194	cytolytic granule
0.37	GO:0042588	zymogen granule
0.36	GO:0070820	tertiary granule
0.36	GO:0031983	vesicle lumen
0.36	GO:0005775	vacuolar lumen
0.36	GO:0045335	phagocytic vesicle

sp|Q9BQ13|KCD14_HUMAN
BTB/POZ domain-containing protein KCTD14
Search

KCTD14

0.97	Potassium channel tetramerization domain containing 14

0.78	GO:0051260	protein homooligomerization
0.38	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.36	GO:0017157	regulation of exocytosis
0.35	GO:0006886	intracellular protein transport
0.35	GO:0061025	membrane fusion
0.35	GO:0016192	vesicle-mediated transport
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0006259	DNA metabolic process

0.36	GO:0000149	SNARE binding
0.36	GO:0005484	SNAP receptor activity
0.35	GO:0045145	single-stranded DNA 5'-3' exodeoxyribonuclease activity
0.32	GO:0003676	nucleic acid binding

0.38	GO:0042734	presynaptic membrane
0.37	GO:0045211	postsynaptic membrane
0.37	GO:0043235	receptor complex
0.32	GO:0030054	cell junction
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9BQ15|SOSB1_HUMAN
SOSS complex subunit B1
Search

NABP2

0.95	Nucleic acid binding protein 2

0.65	GO:0010212	response to ionizing radiation
0.64	GO:0070200	establishment of protein localization to telomere
0.63	GO:1904355	positive regulation of telomere capping
0.63	GO:0007093	mitotic cell cycle checkpoint
0.61	GO:0000724	double-strand break repair via homologous recombination
0.39	GO:0051972	regulation of telomerase activity
0.38	GO:0042795	snRNA transcription by RNA polymerase II
0.35	GO:0030001	metal ion transport
0.33	GO:0055085	transmembrane transport

0.64	GO:0098505	G-rich strand telomeric DNA binding
0.62	GO:0070182	DNA polymerase binding
0.41	GO:0061730	C-rich strand telomeric DNA binding
0.40	GO:0003723	RNA binding
0.35	GO:0046873	metal ion transmembrane transporter activity

0.70	GO:0070876	SOSS complex
0.64	GO:0000784	nuclear chromosome, telomeric region
0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q9BQ16|TICN3_HUMAN
Testican-3
Search

SPOCK3

0.95	SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3

0.60	GO:0007165	signal transduction
0.53	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.42	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0010812	negative regulation of cell-substrate adhesion
0.41	GO:0010977	negative regulation of neuron projection development
0.37	GO:0001764	neuron migration
0.37	GO:0021953	central nervous system neuron differentiation
0.35	GO:2000146	negative regulation of cell motility
0.34	GO:0001558	regulation of cell growth
0.33	GO:0007155	cell adhesion

0.69	GO:0005509	calcium ion binding
0.47	GO:0005539	glycosaminoglycan binding
0.45	GO:0008191	metalloendopeptidase inhibitor activity
0.40	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0005615	extracellular space
0.38	GO:0033268	node of Ranvier
0.38	GO:0031594	neuromuscular junction
0.38	GO:0016528	sarcoplasm
0.34	GO:0014069	postsynaptic density
0.30	GO:0016020	membrane

sp|Q9BQ24|ZFY21_HUMAN
Zinc finger FYVE domain-containing protein 21
Search

ZFYVE21

0.96	Zinc finger FYVE domain-containing protein 21

0.38	GO:0006458	'de novo' protein folding
0.38	GO:0042147	retrograde transport, endosome to Golgi
0.38	GO:0061077	chaperone-mediated protein folding
0.37	GO:0046854	phosphatidylinositol phosphorylation

0.53	GO:0046872	metal ion binding
0.39	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.39	GO:0044183	protein binding involved in protein folding
0.37	GO:0051082	unfolded protein binding

0.39	GO:0005768	endosome
0.38	GO:0005925	focal adhesion
0.37	GO:0044433	cytoplasmic vesicle part
0.37	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0005829	cytosol

0.39	EC:2.7.1.150	GO:0000285
0.39	KEGG:R05802	GO:0000285

sp|Q9BQ31|KCNS3_HUMAN
Potassium voltage-gated channel subfamily S member 3
Search

KCNS3

0.97	Potassium voltage-gated channel delayed rectifier subfamily S member 3

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.45	GO:0043266	regulation of potassium ion transport
0.44	GO:0022898	regulation of transmembrane transporter activity
0.37	GO:0050794	regulation of cellular process
0.35	GO:0002791	regulation of peptide secretion
0.34	GO:0051223	regulation of protein transport
0.34	GO:0010817	regulation of hormone levels
0.34	GO:0023051	regulation of signaling

0.78	GO:0005249	voltage-gated potassium channel activity
0.38	GO:0015459	potassium channel regulator activity
0.32	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005829	cytosol
0.44	GO:0048471	perinuclear region of cytoplasm

sp|Q9BQ39|DDX50_HUMAN
ATP-dependent RNA helicase DDX50
Search

DDX50

0.96	DEAD (Asp-Glu-Ala-Asp) box polypeptide 50

0.58

GO:0010501

RNA secondary structure unwinding

0.67	GO:0004386	helicase activity
0.59	GO:0003723	RNA binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008186	RNA-dependent ATPase activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0140098	catalytic activity, acting on RNA

0.65	GO:0005730	nucleolus
0.50	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm

sp|Q9BQ48|RM34_HUMAN
39S ribosomal protein L34, mitochondrial
Search

MRPL34

0.97	Mitochondrial ribosomal protein L34

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly
0.34	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005840	ribosome
0.51	GO:0005759	mitochondrial matrix
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BQ49|SMIM7_HUMAN
Small integral membrane protein 7
Search

SMIM7

0.58	Small integral membrane protein 7 (inferred by orthology to a human protein)

0.33

GO:0008080

N-acetyltransferase activity

0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008080

sp|Q9BQ50|TREX2_HUMAN
Three prime repair exonuclease 2
Search

TREX2

0.95	LOW QUALITY PROTEIN: three prime repair exonuclease 1

0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.59	GO:0006974	cellular response to DNA damage stimulus
0.55	GO:0006259	DNA metabolic process
0.37	GO:0035458	cellular response to interferon-beta
0.35	GO:0032479	regulation of type I interferon production
0.34	GO:0031570	DNA integrity checkpoint
0.33	GO:0007049	cell cycle
0.33	GO:0032259	methylation
0.32	GO:0032392	DNA geometric change
0.32	GO:0009059	macromolecule biosynthetic process

0.68	GO:0008408	3'-5' exonuclease activity
0.55	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.55	GO:0042803	protein homodimerization activity
0.51	GO:0003676	nucleic acid binding
0.50	GO:0032407	MutSalpha complex binding
0.50	GO:0032405	MutLalpha complex binding
0.49	GO:0000287	magnesium ion binding
0.40	GO:0051011	microtubule minus-end binding
0.38	GO:0032558	adenyl deoxyribonucleotide binding
0.33	GO:0008168	methyltransferase activity

0.43	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.36	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

0.55

EC:3.1.11

GO:0016895

sp|Q9BQ51|PD1L2_HUMAN
Programmed cell death 1 ligand 2
Search

PDCD1LG2

0.97	Programmed cell death ligand 2

0.68	GO:0046007	negative regulation of activated T cell proliferation
0.67	GO:0032693	negative regulation of interleukin-10 production
0.66	GO:0032689	negative regulation of interferon-gamma production
0.64	GO:0042102	positive regulation of T cell proliferation
0.40	GO:0031295	T cell costimulation
0.38	GO:0006955	immune response
0.35	GO:0070234	positive regulation of T cell apoptotic process
0.35	GO:1905402	regulation of activated CD8-positive, alpha-beta T cell apoptotic process
0.35	GO:2001181	positive regulation of interleukin-10 secretion
0.34	GO:0006511	ubiquitin-dependent protein catabolic process

0.35

GO:0005515

protein binding

0.41	GO:0070062	extracellular exosome
0.36	GO:0012505	endomembrane system
0.36	GO:0005886	plasma membrane
0.33	GO:0009986	cell surface
0.33	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

sp|Q9BQ52|RNZ2_HUMAN
Zinc phosphodiesterase ELAC protein 2
Search

ELAC2

0.96	Zinc phosphodiesterase ELAC protein 2

0.67	GO:0072684	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic
0.37	GO:0090646	mitochondrial tRNA processing

0.49	GO:0042781	3'-tRNA processing endoribonuclease activity
0.39	GO:0004549	tRNA-specific ribonuclease activity
0.37	GO:0046872	metal ion binding
0.35	GO:0003723	RNA binding

0.57	GO:0042645	mitochondrial nucleoid
0.52	GO:0005654	nucleoplasm

sp|Q9BQ61|CS043_HUMAN
Uncharacterized protein C19orf43
Search

TRIR

0.97	Telomerase RNA component interacting RNase

0.78	GO:0016075	rRNA catabolic process
0.75	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.33	GO:0006396	RNA processing

0.76	GO:0008409	5'-3' exonuclease activity
0.71	GO:0008408	3'-5' exonuclease activity
0.39	GO:0003723	RNA binding
0.37	GO:0005515	protein binding

0.37

GO:0005739

mitochondrion

sp|Q9BQ65|USB1_HUMAN
U6 snRNA phosphodiesterase
Search

USB1

0.81	U6 snRNA phosphodiesterase

0.85	GO:0034477	U6 snRNA 3'-end processing
0.69	GO:0008380	RNA splicing
0.65	GO:0006397	mRNA processing
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0030223	neutrophil differentiation
0.42	GO:0043484	regulation of RNA splicing
0.35	GO:0006508	proteolysis
0.35	GO:0035987	endodermal cell differentiation
0.32	GO:0006414	translational elongation

0.63	GO:0004518	nuclease activity
0.48	GO:0140098	catalytic activity, acting on RNA
0.36	GO:0008237	metallopeptidase activity
0.35	GO:0004175	endopeptidase activity
0.34	GO:0008270	zinc ion binding
0.32	GO:0003735	structural constituent of ribosome

0.60	GO:0045171	intercellular bridge
0.58	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.35	GO:0005887	integral component of plasma membrane
0.32	GO:0005840	ribosome

0.63

EC:3.1

GO:0004518

sp|Q9BQ66|KR412_HUMAN
Keratin-associated protein 4-12
Search

0.95	Keratin associated protein 4-9

0.43	GO:0042633	hair cycle
0.42	GO:0031424	keratinization
0.42	GO:0007568	aging

0.36

GO:0005515

protein binding

0.83	GO:0045095	keratin filament
0.38	GO:0005829	cytosol

sp|Q9BQ67|GRWD1_HUMAN
Glutamate-rich WD repeat-containing protein 1
Search

GRWD1

0.92	Glutamate-rich WD repeat-containing protein 1

0.55	GO:0031498	chromatin disassembly
0.55	GO:0032986	protein-DNA complex disassembly
0.52	GO:0006334	nucleosome assembly
0.46	GO:0006260	DNA replication
0.34	GO:0016573	histone acetylation
0.34	GO:0060079	excitatory postsynaptic potential
0.34	GO:0042254	ribosome biogenesis
0.34	GO:0035235	ionotropic glutamate receptor signaling pathway
0.33	GO:0065009	regulation of molecular function
0.33	GO:0034220	ion transmembrane transport

0.52	GO:0042393	histone binding
0.52	GO:0003688	DNA replication origin binding
0.51	GO:0003682	chromatin binding
0.34	GO:0004402	histone acetyltransferase activity
0.34	GO:0051082	unfolded protein binding
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity
0.34	GO:0003723	RNA binding
0.34	GO:0004970	ionotropic glutamate receptor activity
0.33	GO:0005085	guanyl-nucleotide exchange factor activity
0.32	GO:0061778	intracellular chloride channel activity

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.47	GO:0005829	cytosol
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part
0.34	GO:0098794	postsynapse
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.3.1.48

GO:0004402

sp|Q9BQ69|MACD1_HUMAN
O-acetyl-ADP-ribose deacetylase MACROD1
Search

MACROD1

0.91	MACRO domain containing protein 1

0.82	GO:0051725	protein de-ADP-ribosylation
0.64	GO:0042278	purine nucleoside metabolic process
0.60	GO:0006974	cellular response to DNA damage stimulus
0.43	GO:0007420	brain development
0.35	GO:0071897	DNA biosynthetic process
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation

0.68	GO:0019213	deacetylase activity
0.60	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.40	GO:0003677	DNA binding
0.38	GO:0005515	protein binding
0.36	GO:0008408	3'-5' exonuclease activity
0.35	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.61	GO:0031981	nuclear lumen
0.54	GO:0005739	mitochondrion
0.43	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

0.60

EC:3.2

GO:0016798

sp|Q9BQ70|TCF25_HUMAN
Transcription factor 25
Search

TCF25

0.92	Transcription factor 25 (Basic helix-loop-helix)

0.77	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0045010	actin nucleation
0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0007507	heart development
0.37	GO:0006351	transcription, DNA-templated

0.60	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003779	actin binding
0.37	GO:0003677	DNA binding

0.60

GO:0005634

nucleus

sp|Q9BQ75|CMS1_HUMAN
Protein CMSS1
Search

CMSS1

0.97	Cms1 ribosomal small subunit homolog

0.81	GO:0030686	90S preribosome
0.61	GO:0005634	nucleus

sp|Q9BQ83|SLX1_HUMAN
Structure-specific endonuclease subunit SLX1
Search

0.75	Structure-specific endonuclease subunit SLX1

0.62	GO:0006310	DNA recombination
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.62	GO:0006281	DNA repair
0.59	GO:1904431	positive regulation of t-circle formation
0.59	GO:0001325	formation of extrachromosomal circular DNA
0.59	GO:0090737	telomere maintenance via telomere trimming
0.39	GO:0061820	telomeric D-loop disassembly
0.39	GO:1904357	negative regulation of telomere maintenance via telomere lengthening
0.38	GO:0010833	telomere maintenance via telomere lengthening

0.78	GO:0017108	5'-flap endonuclease activity
0.59	GO:0008821	crossover junction endodeoxyribonuclease activity
0.45	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.81	GO:0033557	Slx1-Slx4 complex
0.36	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.59

EC:3.1.22.4

GO:0008821

sp|Q9BQ87|TBL1Y_HUMAN
F-box-like/WD repeat-containing protein TBL1Y
Search

TBL1X

0.95	Transducin beta like 1, Y-linked

0.72	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.69	GO:1903507	negative regulation of nucleic acid-templated transcription
0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.65	GO:0016575	histone deacetylation
0.65	GO:0045893	positive regulation of transcription, DNA-templated
0.63	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.60	GO:0010629	negative regulation of gene expression
0.59	GO:0045444	fat cell differentiation
0.57	GO:0007605	sensory perception of sound
0.56	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.78	GO:0003714	transcription corepressor activity
0.71	GO:0008013	beta-catenin binding
0.68	GO:0042393	histone binding
0.65	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0047485	protein N-terminus binding
0.53	GO:0008022	protein C-terminus binding
0.50	GO:0019904	protein domain specific binding
0.50	GO:0003682	chromatin binding
0.48	GO:0008134	transcription factor binding
0.42	GO:0042802	identical protein binding

0.75	GO:0000118	histone deacetylase complex
0.70	GO:0005876	spindle microtubule
0.69	GO:0017053	transcriptional repressor complex
0.49	GO:0005667	transcription factor complex
0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BQ89|F110A_HUMAN
Protein FAM110A
Search

FAM110A

0.68	Serine threonine rich protein

0.43

GO:0005515

protein binding

0.62	GO:0005815	microtubule organizing center
0.61	GO:0000922	spindle pole
0.59	GO:0005829	cytosol
0.53	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BQ90|KLDC3_HUMAN
Kelch domain-containing protein 3
Search

KLHDC3

0.95	Kelch domain-containing protein 3

0.62	GO:0000469	cleavage involved in rRNA processing
0.44	GO:0051321	meiotic cell cycle
0.39	GO:0036498	IRE1-mediated unfolded protein response
0.38	GO:0035825	homologous recombination
0.37	GO:0000280	nuclear division
0.36	GO:0022402	cell cycle process
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0035556	intracellular signal transduction

0.71	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding

0.69	GO:0000790	nuclear chromatin
0.64	GO:0005654	nucleoplasm
0.55	GO:0005730	nucleolus
0.46	GO:0005737	cytoplasm

sp|Q9BQ95|ECSIT_HUMAN
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
Search

ECSIT

0.96	ECSIT signalling integrator

0.84	GO:0051341	regulation of oxidoreductase activity
0.53	GO:0045087	innate immune response
0.52	GO:0055114	oxidation-reduction process
0.44	GO:0001707	mesoderm formation
0.44	GO:0030509	BMP signaling pathway
0.41	GO:0032981	mitochondrial respiratory chain complex I assembly

0.66	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.39	GO:0005515	protein binding
0.39	GO:0004871	signal transducer activity
0.38	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003676	nucleic acid binding

0.68	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.60	GO:0005739	mitochondrion
0.41	GO:0005667	transcription factor complex
0.37	GO:0019866	organelle inner membrane

0.66

EC:1.6

GO:0016651

sp|Q9BQA1|MEP50_HUMAN
Methylosome protein 50
Search

WDR77

0.96	Testis tissue sperm-binding protein Li 44a

0.85	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
0.85	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development
0.74	GO:0008284	positive regulation of cell proliferation
0.66	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0035246	peptidyl-arginine N-methylation
0.39	GO:0000387	spliceosomal snRNP assembly
0.37	GO:0005975	carbohydrate metabolic process

0.84	GO:0008327	methyl-CpG binding
0.80	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.41	GO:0008061	chitin binding
0.40	GO:0016274	protein-arginine N-methyltransferase activity
0.38	GO:0005515	protein binding

0.84	GO:0034709	methylosome
0.68	GO:0005794	Golgi apparatus
0.67	GO:0005829	cytosol
0.67	GO:0005654	nucleoplasm
0.33	GO:0043234	protein complex

0.40

GO:0016274

sp|Q9BQA5|HINFP_HUMAN
Histone H4 transcription factor
Search

HINFP

0.95	Histone H4 transcription factor

0.59	GO:0045445	myoblast differentiation
0.58	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.55	GO:0000077	DNA damage checkpoint
0.54	GO:0001701	in utero embryonic development
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.48	GO:0045184	establishment of protein localization
0.47	GO:0006281	DNA repair
0.44	GO:0006351	transcription, DNA-templated

0.57	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0042393	histone binding
0.55	GO:0003713	transcription coactivator activity
0.54	GO:0003682	chromatin binding
0.51	GO:0019899	enzyme binding
0.36	GO:0046872	metal ion binding
0.33	GO:0016887	ATPase activity
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.58	GO:0015030	Cajal body
0.37	GO:0005730	nucleolus

0.33

EC:3.6.1.3

GO:0016887

sp|Q9BQA9|CQ062_HUMAN
Uncharacterized protein C17orf62
Search

0.34

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q9BQB4|SOST_HUMAN
Sclerostin
Search

SOST

0.97	LOW QUALITY PROTEIN: sclerostin

0.78	GO:0030279	negative regulation of ossification
0.62	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
0.62	GO:0030514	negative regulation of BMP signaling pathway
0.61	GO:0071374	cellular response to parathyroid hormone stimulus
0.60	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.56	GO:0009612	response to mechanical stimulus
0.55	GO:0031333	negative regulation of protein complex assembly
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:2000016	negative regulation of determination of dorsal identity
0.46	GO:0010454	negative regulation of cell fate commitment

0.51	GO:0008134	transcription factor binding
0.47	GO:0098821	BMP receptor activity
0.46	GO:0036122	BMP binding
0.42	GO:0008201	heparin binding
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity

0.73	GO:0005615	extracellular space
0.53	GO:0031012	extracellular matrix
0.38	GO:0005794	Golgi apparatus
0.36	GO:0043234	protein complex

0.33

GO:0008138

sp|Q9BQB6|VKOR1_HUMAN
Vitamin K epoxide reductase complex subunit 1
Search

VKORC1

0.93	Vitamin K epoxide reductase complex

0.50	GO:0042373	vitamin K metabolic process
0.47	GO:0017187	peptidyl-glutamic acid carboxylation
0.47	GO:0007596	blood coagulation
0.42	GO:0060348	bone development
0.40	GO:0050820	positive regulation of coagulation
0.39	GO:0017144	drug metabolic process
0.38	GO:0055114	oxidation-reduction process
0.36	GO:0042362	fat-soluble vitamin biosynthetic process
0.36	GO:0030193	regulation of blood coagulation
0.35	GO:0010243	response to organonitrogen compound

0.52	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor
0.39	GO:0048038	quinone binding

0.45	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:1.1.4

GO:0016900

sp|Q9BQC3|DPH2_HUMAN
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2
Search

DPH2

0.75	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

0.81	GO:0017182	peptidyl-diphthamide metabolic process
0.81	GO:1900247	regulation of cytoplasmic translational elongation
0.48	GO:0009058	biosynthetic process
0.35	GO:0015991	ATP hydrolysis coupled proton transport

0.50	GO:0016740	transferase activity
0.36	GO:0005515	protein binding
0.34	GO:0015078	hydrogen ion transmembrane transporter activity

0.36	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.50

EC:2

GO:0016740

sp|Q9BQC6|RT63_HUMAN
Ribosomal protein 63, mitochondrial
Search

MRPL57

0.97	Mitochondrial ribosomal protein 63

0.46	GO:0043043	peptide biosynthetic process
0.43	GO:0044267	cellular protein metabolic process
0.42	GO:0010467	gene expression
0.42	GO:0009059	macromolecule biosynthetic process
0.36	GO:0043624	cellular protein complex disassembly

0.47

GO:0003735

structural constituent of ribosome

0.79	GO:0005761	mitochondrial ribosome
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|Q9BQD1|MCHL2_HUMAN
Putative pro-MCH-like protein 2
Search

PMCHL1

0.97	Melanin-concentrating hormone (Fragment)

0.78	GO:0007268	chemical synaptic transmission
0.76	GO:0010469	regulation of receptor activity
0.61	GO:0007631	feeding behavior
0.40	GO:0007218	neuropeptide signaling pathway
0.37	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep
0.37	GO:0032227	negative regulation of synaptic transmission, dopaminergic
0.36	GO:0007595	lactation
0.36	GO:0045776	negative regulation of blood pressure
0.36	GO:0048168	regulation of neuronal synaptic plasticity
0.36	GO:0002027	regulation of heart rate

0.87	GO:0030354	melanin-concentrating hormone activity
0.37	GO:0031777	type 1 melanin-concentrating hormone receptor binding

0.48	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q9BQD3|KXDL1_HUMAN
KxDL motif-containing protein 1
Search

KXD1

0.97	KxDL motif-containing protein 1

0.75	GO:0032418	lysosome localization
0.63	GO:0016192	vesicle-mediated transport
0.44	GO:0043043	peptide biosynthetic process
0.42	GO:0044267	cellular protein metabolic process
0.41	GO:0010467	gene expression
0.40	GO:0009059	macromolecule biosynthetic process
0.34	GO:0045892	negative regulation of transcription, DNA-templated

0.45	GO:0003735	structural constituent of ribosome
0.38	GO:0005515	protein binding
0.36	GO:0003723	RNA binding
0.35	GO:0003714	transcription corepressor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.79	GO:0099078	BORC complex
0.77	GO:0031083	BLOC-1 complex
0.52	GO:0005765	lysosomal membrane
0.44	GO:0005840	ribosome
0.36	GO:0032021	NELF complex

sp|Q9BQD7|F173A_HUMAN
Protein FAM173A
Search

sp|Q9BQE3|TBA1C_HUMAN
Tubulin alpha-1C chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.45	GO:0071353	cellular response to interleukin-4
0.37	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0051301	cell division
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0018410	C-terminal protein amino acid modification

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0003725	double-stranded RNA binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0019904	protein domain specific binding

0.73	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.45	GO:0043209	myelin sheath
0.39	GO:0045121	membrane raft
0.39	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.38	GO:0035770	ribonucleoprotein granule
0.37	GO:0005615	extracellular space
0.36	GO:0012505	endomembrane system
0.36	GO:0005634	nucleus

sp|Q9BQE4|SELS_HUMAN
Selenoprotein S
Search

SELENOS

0.97	LOW QUALITY PROTEIN: selenoprotein S

0.68	GO:0006886	intracellular protein transport
0.59	GO:0080164	regulation of nitric oxide metabolic process
0.59	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus
0.59	GO:2000110	negative regulation of macrophage apoptotic process
0.58	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
0.57	GO:0032715	negative regulation of interleukin-6 production
0.57	GO:0006983	ER overload response
0.57	GO:0032720	negative regulation of tumor necrosis factor production
0.57	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.56	GO:1903513	endoplasmic reticulum to cytosol transport

0.57	GO:1990381	ubiquitin-specific protease binding
0.55	GO:0051117	ATPase binding
0.48	GO:0016209	antioxidant activity
0.34	GO:0004872	receptor activity

0.76	GO:0030176	integral component of endoplasmic reticulum membrane
0.59	GO:0036502	Derlin-1-VIMP complex
0.57	GO:0034362	low-density lipoprotein particle
0.56	GO:0036513	Derlin-1 retrotranslocation complex
0.56	GO:0005881	cytoplasmic microtubule
0.56	GO:0034361	very-low-density lipoprotein particle
0.33	GO:0005886	plasma membrane

sp|Q9BQE5|APOL2_HUMAN
Apolipoprotein L2
Search

APOL1

0.95	Apolipoprotein L-I

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.38	GO:0008203	cholesterol metabolic process
0.37	GO:0006954	inflammatory response
0.37	GO:0060135	maternal process involved in female pregnancy
0.35	GO:0007275	multicellular organism development
0.35	GO:0043687	post-translational protein modification
0.35	GO:0031640	killing of cells of other organism
0.35	GO:0045087	innate immune response
0.35	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.72	GO:0008289	lipid binding
0.38	GO:0008035	high-density lipoprotein particle binding
0.35	GO:0005102	receptor binding
0.35	GO:0005254	chloride channel activity
0.34	GO:0005319	lipid transporter activity
0.33	GO:0004871	signal transducer activity

0.66	GO:0005576	extracellular region
0.36	GO:0044432	endoplasmic reticulum part
0.35	GO:1990777	lipoprotein particle
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.34	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BQE6|LBHD1_HUMAN
LBH domain-containing protein 1
Search

LBHD1

0.97	LBH domain-containing protein 1

sp|Q9BQE9|BCL7B_HUMAN
B-cell CLL/lymphoma 7 protein family member B
Search

BCL7B

0.91	B-cell CLL/lymphoma 7 protein family member B-A

0.68	GO:0006915	apoptotic process
0.68	GO:0016055	Wnt signaling pathway
0.64	GO:0030154	cell differentiation

0.51

GO:0003779

actin binding

sp|Q9BQF6|SENP7_HUMAN
Sentrin-specific protease 7
Search

SENP7

0.96	Sentrin-specific protease 7

0.60	GO:0006508	proteolysis
0.49	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.38	GO:0007601	visual perception

0.72	GO:0008234	cysteine-type peptidase activity
0.45	GO:0004930	G-protein coupled receptor activity
0.39	GO:0005540	hyaluronic acid binding
0.38	GO:0005201	extracellular matrix structural constituent
0.35	GO:0005515	protein binding

0.48	GO:0005634	nucleus
0.40	GO:0033165	interphotoreceptor matrix
0.40	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0008234

sp|Q9BQG0|MBB1A_HUMAN
Myb-binding protein 1A
Search

MYBBP1A

0.95	Myb-binding protein 1A

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:2000210	positive regulation of anoikis
0.62	GO:0071158	positive regulation of cell cycle arrest
0.62	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.61	GO:0032922	circadian regulation of gene expression
0.61	GO:0042149	cellular response to glucose starvation
0.58	GO:0006351	transcription, DNA-templated
0.54	GO:0006913	nucleocytoplasmic transport
0.53	GO:0045892	negative regulation of transcription, DNA-templated
0.51	GO:0022904	respiratory electron transport chain

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.59	GO:0001047	core promoter binding
0.59	GO:0003714	transcription corepressor activity
0.38	GO:0043565	sequence-specific DNA binding
0.38	GO:0008134	transcription factor binding
0.35	GO:0003723	RNA binding
0.34	GO:0008270	zinc ion binding

0.64	GO:0042564	NLS-dependent protein nuclear import complex
0.55	GO:0005730	nucleolus
0.41	GO:0005737	cytoplasm
0.36	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.71

EC:2.7.7.7

GO:0003887

sp|Q9BQG1|SYT3_HUMAN
Synaptotagmin-3
Search

SYT3

0.88	Synaptotagmin III

0.73	GO:0017156	calcium ion regulated exocytosis
0.69	GO:0017158	regulation of calcium ion-dependent exocytosis
0.62	GO:1903861	positive regulation of dendrite extension
0.50	GO:0048489	synaptic vesicle transport
0.50	GO:0099504	synaptic vesicle cycle
0.50	GO:0006906	vesicle fusion
0.50	GO:0099643	signal release from synapse
0.50	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.47	GO:0050796	regulation of insulin secretion
0.47	GO:0006836	neurotransmitter transport

0.50	GO:0000149	SNARE binding
0.49	GO:0005544	calcium-dependent phospholipid binding
0.49	GO:0030276	clathrin binding
0.46	GO:0005509	calcium ion binding
0.38	GO:0001786	phosphatidylserine binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.54	GO:0005768	endosome
0.48	GO:0098793	presynapse
0.40	GO:0005886	plasma membrane
0.37	GO:0070382	exocytic vesicle
0.30	GO:0016021	integral component of membrane
0.30	GO:0098588	bounding membrane of organelle
0.30	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0098805	whole membrane

sp|Q9BQG2|NUD12_HUMAN
Peroxisomal NADH pyrophosphatase NUDT12
Search

NUDT12

0.96	Nudix (Nucleoside diphosphate linked moiety X)-type motif 12

0.63	GO:0019677	NAD catabolic process
0.58	GO:0006742	NADP catabolic process
0.36	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway

0.59	GO:0000210	NAD+ diphosphatase activity
0.58	GO:0035529	NADH pyrophosphatase activity
0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.54	GO:0005777	peroxisome
0.46	GO:0005634	nucleus
0.35	GO:0031907	microbody lumen
0.30	GO:0031224	intrinsic component of membrane

0.59	EC:3.6.1.22	GO:0000210
0.58	KEGG:R00103	GO:0035529

sp|Q9BQI0|AIF1L_HUMAN
Allograft inflammatory factor 1-like
Search

AIF1L

0.95	Allograft inflammatory factor 1 like

0.52	GO:0071673	positive regulation of smooth muscle cell chemotaxis
0.50	GO:0016601	Rac protein signal transduction
0.50	GO:0071672	negative regulation of smooth muscle cell chemotaxis
0.50	GO:2000406	positive regulation of T cell migration
0.50	GO:0090026	positive regulation of monocyte chemotaxis
0.50	GO:0048661	positive regulation of smooth muscle cell proliferation
0.50	GO:0097178	ruffle assembly
0.49	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.49	GO:0071346	cellular response to interferon-gamma
0.49	GO:0006911	phagocytosis, engulfment

0.76	GO:0051015	actin filament binding
0.67	GO:0005509	calcium ion binding

0.55	GO:0005884	actin filament
0.51	GO:0032587	ruffle membrane
0.50	GO:0001891	phagocytic cup
0.48	GO:0030027	lamellipodium
0.47	GO:0005925	focal adhesion
0.46	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.39	GO:0043204	perikaryon
0.36	GO:0070062	extracellular exosome

sp|Q9BQI3|E2AK1_HUMAN
Eukaryotic translation initiation factor 2-alpha kinase 1
Search

EIF2AK1

0.93	Eukaryotic initiation factor 2 alpha kinase

0.64	GO:0046986	negative regulation of hemoglobin biosynthetic process
0.63	GO:0010999	regulation of eIF2 alpha phosphorylation by heme
0.63	GO:0006468	protein phosphorylation
0.62	GO:1990641	response to iron ion starvation
0.60	GO:0030225	macrophage differentiation
0.60	GO:0006413	translational initiation
0.59	GO:0043558	regulation of translational initiation in response to stress
0.59	GO:0002526	acute inflammatory response
0.57	GO:0006909	phagocytosis
0.55	GO:0008285	negative regulation of cell proliferation

0.64	GO:0004672	protein kinase activity
0.60	GO:0003743	translation initiation factor activity
0.58	GO:0045182	translation regulator activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0042803	protein homodimerization activity
0.47	GO:0020037	heme binding

0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9BQI4|CCDC3_HUMAN
Coiled-coil domain-containing protein 3
Search

CCDC3

0.93	Coiled-coil domain-containing protein 3

0.86	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.85	GO:0045600	positive regulation of fat cell differentiation
0.84	GO:0046889	positive regulation of lipid biosynthetic process

0.70	GO:0005783	endoplasmic reticulum
0.65	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q9BQI5|SGIP1_HUMAN
SH3-containing GRB2-like protein 3-interacting protein 1
Search

SGIP1

0.87	SH3 domain GRB2 like endophilin interacting protein 1

0.70	GO:0072583	clathrin-dependent endocytosis
0.65	GO:0097320	plasma membrane tubulation
0.65	GO:0048260	positive regulation of receptor-mediated endocytosis
0.41	GO:0015031	protein transport
0.39	GO:2000507	positive regulation of energy homeostasis
0.39	GO:2000253	positive regulation of feeding behavior
0.38	GO:0002021	response to dietary excess

0.60	GO:0017124	SH3 domain binding
0.58	GO:0005543	phospholipid binding
0.57	GO:0008017	microtubule binding

0.64	GO:0030122	AP-2 adaptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BQI6|SLF1_HUMAN
SMC5-SMC6 complex localization factor protein 1
Search

SLF1

0.96	BRCT domain-containing protein 1

0.86	GO:1990166	protein localization to site of double-strand break
0.86	GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion
0.85	GO:2000781	positive regulation of double-strand break repair
0.76	GO:0031334	positive regulation of protein complex assembly
0.64	GO:0006974	cellular response to DNA damage stimulus
0.42	GO:0031297	replication fork processing
0.38	GO:0006310	DNA recombination
0.35	GO:0032509	endosome transport via multivesicular body sorting pathway
0.33	GO:0043065	positive regulation of apoptotic process
0.33	GO:0015031	protein transport

0.77	GO:0031625	ubiquitin protein ligase binding
0.73	GO:0032403	protein complex binding
0.41	GO:0042393	histone binding
0.33	GO:0003714	transcription corepressor activity

0.85	GO:0042405	nuclear inclusion body
0.81	GO:0035861	site of double-strand break
0.75	GO:0005813	centrosome
0.72	GO:0000786	nucleosome
0.48	GO:0005737	cytoplasm
0.42	GO:0035101	FACT complex
0.42	GO:0005662	DNA replication factor A complex
0.41	GO:0042555	MCM complex
0.40	GO:0016604	nuclear body
0.34	GO:0031436	BRCA1-BARD1 complex

sp|Q9BQI7|PSD2_HUMAN
PH and SEC7 domain-containing protein 2
Search

PSD2

0.97	PH and SEC7 domain-containing protein 2

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.45	GO:0008345	larval locomotory behavior
0.44	GO:0061053	somite development
0.42	GO:0007507	heart development
0.33	GO:0016192	vesicle-mediated transport

0.81	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.71	GO:0005543	phospholipid binding

0.58	GO:0032587	ruffle membrane
0.57	GO:0032154	cleavage furrow
0.55	GO:0043025	neuronal cell body
0.55	GO:0030425	dendrite
0.33	GO:0005802	trans-Golgi network
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BQI9|NRIP2_HUMAN
Nuclear receptor-interacting protein 2
Search

NRIP2

0.97	Nuclear receptor-interacting protein 2

0.58	GO:0006508	proteolysis
0.39	GO:0007219	Notch signaling pathway
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.66	GO:0070001	aspartic-type peptidase activity
0.62	GO:0004175	endopeptidase activity
0.36	GO:0005515	protein binding

0.40	GO:0005737	cytoplasm
0.37	GO:0005634	nucleus

sp|Q9BQJ4|TMM47_HUMAN
Transmembrane protein 47
Search

TMEM47

0.96	transmembrane protein 47

0.33

GO:0005515

protein binding

0.49	GO:0030054	cell junction
0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q9BQK8|LPIN3_HUMAN
Phosphatidate phosphatase LPIN3
Search

LPIN3

0.86	Phosphatidate phosphatase LPIN3

0.68	GO:0016311	dephosphorylation
0.68	GO:0019432	triglyceride biosynthetic process
0.63	GO:0009062	fatty acid catabolic process
0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:0006656	phosphatidylcholine biosynthetic process
0.40	GO:0006646	phosphatidylethanolamine biosynthetic process

0.85	GO:0008195	phosphatidate phosphatase activity
0.59	GO:0003713	transcription coactivator activity

0.49	GO:0005634	nucleus
0.38	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005741	mitochondrial outer membrane

0.85

EC:3.1.3.4

GO:0008195

sp|Q9BQL6|FERM1_HUMAN
Fermitin family homolog 1
Search

FERMT1

0.97	Fermitin family like protein 1

0.80	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0051886	negative regulation of timing of anagen
0.60	GO:0051546	keratinocyte migration
0.60	GO:2001203	positive regulation of transforming growth factor-beta secretion
0.59	GO:0043616	keratinocyte proliferation
0.58	GO:0035414	negative regulation of catenin import into nucleus
0.57	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.57	GO:0090162	establishment of epithelial cell polarity
0.57	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.57	GO:2000647	negative regulation of stem cell proliferation

0.45

GO:0005547

phosphatidylinositol-3,4,5-trisphosphate binding

0.59	GO:0031941	filamentous actin
0.58	GO:0005925	focal adhesion
0.48	GO:0005829	cytosol
0.43	GO:0097517	contractile actin filament bundle
0.43	GO:0042641	actomyosin
0.43	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0005654	nucleoplasm
0.39	GO:0014704	intercalated disc
0.39	GO:0031256	leading edge membrane
0.39	GO:0031253	cell projection membrane

sp|Q9BQM9|CT144_HUMAN
Uncharacterized protein C20orf144
Search

sp|Q9BQN1|FA83C_HUMAN
Protein FAM83C
Search

0.74	GO:0007173	epidermal growth factor receptor signaling pathway
0.69	GO:0008283	cell proliferation
0.52	GO:0030509	BMP signaling pathway
0.38	GO:0045104	intermediate filament cytoskeleton organization

0.78	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.73	GO:0019901	protein kinase binding

0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.38	GO:0045095	keratin filament

sp|Q9BQP7|MGME1_HUMAN
Mitochondrial genome maintenance exonuclease 1
Search

MGME1

0.95	Mitochondrial genome maintenance exonuclease 1

0.85	GO:0043504	mitochondrial DNA repair
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.62	GO:0006264	mitochondrial DNA replication

0.83

GO:0008297

single-stranded DNA exodeoxyribonuclease activity

0.59

GO:0005739

mitochondrion

sp|Q9BQP9|BPIA3_HUMAN
BPI fold-containing family A member 3
Search

BPIFA3

0.97	BPI fold-containing family A member 3

0.72

GO:0008289

lipid binding

0.41

GO:0005576

extracellular region

sp|Q9BQQ3|GORS1_HUMAN
Golgi reassembly-stacking protein 1
Search

GORASP1

0.97	Golgi reassembly-stacking protein 1

0.84	GO:0050774	negative regulation of dendrite morphogenesis
0.79	GO:0007030	Golgi organization
0.76	GO:0006487	protein N-linked glycosylation
0.41	GO:0015031	protein transport
0.41	GO:0048208	COPII vesicle coating
0.40	GO:1904668	positive regulation of ubiquitin protein ligase activity

0.40

GO:0005515

protein binding

0.71	GO:0005794	Golgi apparatus
0.41	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.40	GO:0031984	organelle subcompartment

sp|Q9BQQ7|RTP3_HUMAN
Receptor-transporting protein 3
Search

RTP3

0.93	Receptor-transporting protein 3

0.79	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.68	GO:0006612	protein targeting to membrane
0.55	GO:0051205	protein insertion into membrane

0.64

GO:0031849

olfactory receptor binding

0.55	GO:0009986	cell surface
0.44	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9BQR3|PRS27_HUMAN
Serine protease 27
Search

PRSS27

0.71	Coagulation factor XI

0.61	GO:0006508	proteolysis
0.49	GO:0007597	blood coagulation, intrinsic pathway
0.46	GO:0051604	protein maturation
0.44	GO:0051919	positive regulation of fibrinolysis
0.41	GO:0006898	receptor-mediated endocytosis
0.38	GO:0014909	smooth muscle cell migration
0.37	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.37	GO:0001666	response to hypoxia
0.37	GO:0030162	regulation of proteolysis
0.36	GO:0042730	fibrinolysis

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0005044	scavenger receptor activity
0.37	GO:0051219	phosphoprotein binding
0.36	GO:0005102	receptor binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0004497	monooxygenase activity

0.49	GO:0005576	extracellular region
0.47	GO:0046658	anchored component of plasma membrane
0.45	GO:0019897	extrinsic component of plasma membrane
0.37	GO:0030141	secretory granule
0.37	GO:0045177	apical part of cell
0.36	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.69

EC:3.4.21

GO:0004252

sp|Q9BQS2|SYT15_HUMAN
Synaptotagmin-15
Search

SYT15

0.78	Synaptotagmin XV

0.57	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.56	GO:0017158	regulation of calcium ion-dependent exocytosis
0.55	GO:0006906	vesicle fusion
0.33	GO:0006886	intracellular protein transport
0.33	GO:0048488	synaptic vesicle endocytosis

0.56	GO:0005544	calcium-dependent phospholipid binding
0.55	GO:0019905	syntaxin binding
0.54	GO:0030276	clathrin binding
0.49	GO:0005509	calcium ion binding
0.36	GO:0017137	Rab GTPase binding

0.58	GO:0019898	extrinsic component of membrane
0.53	GO:0098793	presynapse
0.42	GO:0005886	plasma membrane
0.36	GO:0070382	exocytic vesicle
0.32	GO:0030658	transport vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|Q9BQS6|HSPB9_HUMAN
Heat shock protein beta-9
Search

HSPB9

0.97	Heat shock protein beta-9

0.40

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

sp|Q9BQS7|HEPH_HUMAN
Hephaestin
Search

HEPHL1

0.64	Hephaestin like 1

0.63	GO:0006879	cellular iron ion homeostasis
0.63	GO:0006826	iron ion transport
0.52	GO:0055114	oxidation-reduction process
0.30	GO:0006825	copper ion transport

0.71	GO:0005507	copper ion binding
0.66	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.30	GO:0005506	iron ion binding

0.48	GO:0005886	plasma membrane
0.30	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0044425	membrane part

0.66

EC:1.16.3

GO:0016724

sp|Q9BQS8|FYCO1_HUMAN
FYVE and coiled-coil domain-containing protein 1
Search

FYCO1

0.96	FYVE and coiled-coil domain-containing protein 1

0.63	GO:1901098	positive regulation of autophagosome maturation
0.61	GO:0072383	plus-end-directed vesicle transport along microtubule
0.47	GO:0006458	'de novo' protein folding
0.46	GO:0061077	chaperone-mediated protein folding
0.33	GO:0007165	signal transduction

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.49	GO:0044183	protein binding involved in protein folding
0.44	GO:0051082	unfolded protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.59	GO:0005776	autophagosome
0.57	GO:0005770	late endosome
0.56	GO:0005764	lysosome
0.52	GO:0005794	Golgi apparatus
0.48	GO:0005832	chaperonin-containing T-complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BQT8|ODC_HUMAN
Mitochondrial 2-oxodicarboxylate carrier
Search

SLC25A21

0.96	LOW QUALITY PROTEIN: mitochondrial 2-oxodicarboxylate carrier

0.45	GO:0006839	mitochondrial transport
0.45	GO:0006835	dicarboxylic acid transport
0.45	GO:0055085	transmembrane transport
0.35	GO:0006554	lysine catabolic process
0.34	GO:0051181	cofactor transport
0.32	GO:0032259	methylation
0.32	GO:0055114	oxidation-reduction process

0.46	GO:0005310	dicarboxylic acid transmembrane transporter activity
0.34	GO:0051184	cofactor transmembrane transporter activity
0.33	GO:0008168	methyltransferase activity
0.32	GO:0016491	oxidoreductase activity

0.41	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0008168

sp|Q9BQT9|CSTN3_HUMAN
Calsyntenin-3
Search

CLSTN3

0.97	Alcadein-beta

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.59	GO:1902474	positive regulation of protein localization to synapse
0.58	GO:0051932	synaptic transmission, GABAergic
0.57	GO:0035249	synaptic transmission, glutamatergic
0.56	GO:0051965	positive regulation of synapse assembly
0.55	GO:0050806	positive regulation of synaptic transmission
0.55	GO:0007416	synapse assembly
0.53	GO:0001558	regulation of cell growth
0.37	GO:1990126	retrograde transport, endosome to plasma membrane
0.37	GO:0050770	regulation of axonogenesis

0.70	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.55	GO:0014069	postsynaptic density
0.53	GO:0045211	postsynaptic membrane
0.51	GO:0009986	cell surface
0.44	GO:0043234	protein complex
0.39	GO:0000139	Golgi membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9BQW3|COE4_HUMAN
Transcription factor COE4
Search

0.84	Early B-cell factor 4

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.53	GO:0008134	transcription factor binding

0.61

GO:0005634

nucleus

sp|Q9BQY4|RHXF2_HUMAN
Rhox homeobox family member 2
Search

0.97	Rhox homeobox family member 2

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.51	GO:0007275	multicellular organism development
0.44	GO:0006351	transcription, DNA-templated
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.41	GO:0060429	epithelium development
0.40	GO:0009653	anatomical structure morphogenesis
0.39	GO:0010604	positive regulation of macromolecule metabolic process
0.34	GO:0007601	visual perception

0.63	GO:0043565	sequence-specific DNA binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9BQY6|WFDC6_HUMAN
WAP four-disulfide core domain protein 6
Search

0.97	WAP four-disulfide core domain protein 6

0.76	GO:0010466	negative regulation of peptidase activity
0.75	GO:0052548	regulation of endopeptidase activity
0.42	GO:0042742	defense response to bacterium
0.41	GO:1901318	negative regulation of flagellated sperm motility
0.41	GO:0090281	negative regulation of calcium ion import
0.38	GO:0051259	protein oligomerization
0.38	GO:0019730	antimicrobial humoral response
0.36	GO:0006508	proteolysis

0.78	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0008233	peptidase activity
0.35	GO:0005515	protein binding

0.64	GO:0005576	extracellular region
0.53	GO:0097223	sperm part
0.51	GO:0030141	secretory granule
0.40	GO:0009986	cell surface
0.36	GO:0043234	protein complex
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0008233

sp|Q9BQY9|DBND2_HUMAN
Dysbindin domain-containing protein 2
Search

DBNDD2

0.87	Dysbindin domain-containing protein 2

0.55	GO:0006469	negative regulation of protein kinase activity
0.49	GO:0031175	neuron projection development
0.41	GO:0060155	platelet dense granule organization
0.41	GO:0001956	positive regulation of neurotransmitter secretion
0.40	GO:0048490	anterograde synaptic vesicle transport
0.40	GO:0014059	regulation of dopamine secretion
0.40	GO:0043506	regulation of JUN kinase activity
0.40	GO:0032091	negative regulation of protein binding
0.39	GO:0016358	dendrite development
0.39	GO:0007596	blood coagulation

0.35

GO:0005515

protein binding

0.52	GO:0030672	synaptic vesicle membrane
0.40	GO:1904115	axon cytoplasm
0.40	GO:0043197	dendritic spine
0.40	GO:0016528	sarcoplasm
0.40	GO:0030426	growth cone
0.40	GO:0042383	sarcolemma
0.39	GO:0031083	BLOC-1 complex
0.39	GO:0014069	postsynaptic density
0.38	GO:0030496	midbody
0.38	GO:0005789	endoplasmic reticulum membrane

sp|Q9BR01|ST4A1_HUMAN
Sulfotransferase 4A1
Search

SULT4A1

0.57	Sulfotransferase

0.47	GO:0006790	sulfur compound metabolic process
0.38	GO:0008202	steroid metabolic process
0.35	GO:0034035	purine ribonucleoside bisphosphate metabolic process
0.34	GO:0016042	lipid catabolic process
0.33	GO:0006163	purine nucleotide metabolic process
0.33	GO:0009259	ribonucleotide metabolic process
0.33	GO:0043436	oxoacid metabolic process
0.33	GO:0045606	positive regulation of epidermal cell differentiation
0.33	GO:0034754	cellular hormone metabolic process
0.33	GO:0008285	negative regulation of cell proliferation

0.78	GO:0008146	sulfotransferase activity
0.51	GO:0042802	identical protein binding
0.34	GO:0005496	steroid binding
0.33	GO:0042562	hormone binding
0.33	GO:0043178	alcohol binding
0.32	GO:0016787	hydrolase activity
0.31	GO:0003676	nucleic acid binding

0.34	GO:0005829	cytosol
0.32	GO:0043231	intracellular membrane-bounded organelle

0.78

GO:0008146

sp|Q9BR09|NEUL2_HUMAN
Neuralized-like protein 2
Search

NEURL2

0.97	Neuralized E3 ubiquitin protein ligase 2

0.70	GO:0016567	protein ubiquitination
0.63	GO:0035556	intracellular signal transduction
0.39	GO:0045214	sarcomere organization
0.37	GO:0043687	post-translational protein modification
0.34	GO:0032447	protein urmylation
0.34	GO:0034227	tRNA thio-modification
0.33	GO:0002098	tRNA wobble uridine modification

0.34	GO:0005515	protein binding
0.33	GO:0000049	tRNA binding
0.33	GO:0016779	nucleotidyltransferase activity

0.45	GO:0005622	intracellular
0.40	GO:0005927	muscle tendon junction
0.36	GO:1990234	transferase complex

0.33

GO:0016779

sp|Q9BR10|SPT25_HUMAN
Spermatogenesis-associated protein 25
Search

sp|Q9BR11|ZSWM1_HUMAN
Zinc finger SWIM domain-containing protein 1
Search

ZSWIM1

0.97	Zinc finger SWIM domain-containing protein 1

0.63

GO:0008270

zinc ion binding

0.52

GO:0005634

nucleus

sp|Q9BR26|OCSTP_HUMAN
Osteoclast stimulatory transmembrane protein
Search

OCSTAMP

0.96	LOW QUALITY PROTEIN: osteoclast stimulatory transmembrane protein

0.80	GO:0090290	positive regulation of osteoclast proliferation
0.80	GO:0034241	positive regulation of macrophage fusion
0.79	GO:0072674	multinuclear osteoclast differentiation
0.76	GO:0045672	positive regulation of osteoclast differentiation
0.76	GO:0071391	cellular response to estrogen stimulus
0.72	GO:0071356	cellular response to tumor necrosis factor

0.30

GO:0044425

membrane part

sp|Q9BR39|JPH2_HUMAN
Junctophilin-2
Search

JPH2

0.87	Junctophilin-2

0.61	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.58	GO:0051209	release of sequestered calcium ion into cytosol
0.56	GO:0055024	regulation of cardiac muscle tissue development
0.42	GO:0032501	multicellular organismal process
0.40	GO:0035640	exploration behavior
0.40	GO:0048168	regulation of neuronal synaptic plasticity
0.40	GO:0048856	anatomical structure development
0.37	GO:0040011	locomotion

0.60	GO:0010314	phosphatidylinositol-5-phosphate binding
0.60	GO:0070300	phosphatidic acid binding
0.59	GO:0001786	phosphatidylserine binding
0.59	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.58	GO:0015278	calcium-release channel activity
0.58	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.58	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.57	GO:0070273	phosphatidylinositol-4-phosphate binding
0.57	GO:0032266	phosphatidylinositol-3-phosphate binding
0.41	GO:0008307	structural constituent of muscle

0.85	GO:0030314	junctional membrane complex
0.59	GO:0016529	sarcoplasmic reticulum
0.57	GO:0030018	Z disc
0.45	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0098588	bounding membrane of organelle
0.39	GO:0005886	plasma membrane
0.38	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9BR46|CT078_HUMAN
Putative uncharacterized protein C20orf78
Search

sp|Q9BR61|ACBD6_HUMAN
Acyl-CoA-binding domain-containing protein 6
Search

ACBD6

0.96	Acyl-CoA-binding domain-containing protein 6

0.35	GO:0006637	acyl-CoA metabolic process
0.34	GO:0000413	protein peptidyl-prolyl isomerization

0.77	GO:0000062	fatty-acyl-CoA binding
0.40	GO:0008289	lipid binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.35

GO:0005737

cytoplasm

0.34

EC:5.2.1.8

GO:0003755

sp|Q9BR76|COR1B_HUMAN
Coronin-1B
Search

CORO1B

0.67

Coronin

0.71	GO:2000394	positive regulation of lamellipodium morphogenesis
0.70	GO:0030036	actin cytoskeleton organization
0.65	GO:0030336	negative regulation of cell migration
0.65	GO:0001667	ameboidal-type cell migration
0.62	GO:1902463	protein localization to cell leading edge
0.62	GO:0071671	regulation of smooth muscle cell chemotaxis
0.61	GO:0051129	negative regulation of cellular component organization
0.60	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.59	GO:0050922	negative regulation of chemotaxis
0.59	GO:0031529	ruffle organization

0.75	GO:0051015	actin filament binding
0.59	GO:0071933	Arp2/3 complex binding
0.56	GO:0045296	cadherin binding
0.54	GO:0048365	Rac GTPase binding
0.52	GO:0042802	identical protein binding

0.71	GO:0015629	actin cytoskeleton
0.65	GO:0030027	lamellipodium
0.56	GO:0016600	flotillin complex
0.55	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0016328	lateral plasma membrane
0.52	GO:0099513	polymeric cytoskeletal fiber
0.50	GO:0005829	cytosol
0.49	GO:0031982	vesicle
0.39	GO:0005925	focal adhesion
0.37	GO:0043230	extracellular organelle

sp|Q9BR77|CCD77_HUMAN
Coiled-coil domain-containing protein 77
Search

CCDC77

0.97	Coiled-coil domain-containing protein 77

0.34

GO:0046872

metal ion binding

0.77	GO:0005813	centrosome
0.30	GO:0016020	membrane

sp|Q9BR84|ZN559_HUMAN
Zinc finger protein 559
Search

0.59	Zinc finger protein 559

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:0042981	regulation of apoptotic process
0.32	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.38	GO:0005515	protein binding
0.32	GO:0004984	olfactory receptor activity
0.32	GO:0004930	G-protein coupled receptor activity

0.43	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.35	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BRA0|LSMD1_HUMAN
N-alpha-acetyltransferase 38, NatC auxiliary subunit
Search

NAA38

0.94	LSM domain-containing protein 1

0.52	GO:0043066	negative regulation of apoptotic process
0.34	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.32	GO:0006281	DNA repair
0.32	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.39	GO:0016740	transferase activity
0.34	GO:0005515	protein binding
0.32	GO:0004518	nuclease activity
0.32	GO:0003677	DNA binding

0.85	GO:0031417	NatC complex
0.54	GO:0005844	polysome
0.45	GO:0005634	nucleus
0.33	GO:0031461	cullin-RING ubiquitin ligase complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:2

GO:0016740

sp|Q9BRA2|TXD17_HUMAN
Thioredoxin domain-containing protein 17
Search

TXNDC17

0.96	Thioredoxin domain-containing protein 17

0.74	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.61	GO:0098869	cellular oxidant detoxification
0.56	GO:0016598	protein arginylation
0.49	GO:0055114	oxidation-reduction process

0.73	GO:0047134	protein-disulfide reductase activity
0.63	GO:0004601	peroxidase activity
0.56	GO:0004057	arginyltransferase activity
0.36	GO:0008233	peptidase activity
0.36	GO:0005515	protein binding

0.62	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.73	EC:1.8.1.8	GO:0047134
0.63	KEGG:R03532	GO:0004601

sp|Q9BRB3|PIGQ_HUMAN
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q
Search

PIGQ

0.92	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

0.76	GO:0006506	GPI anchor biosynthetic process
0.34	GO:0016567	protein ubiquitination
0.34	GO:0005975	carbohydrate metabolic process
0.33	GO:0035556	intracellular signal transduction

0.81	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.4.1.198

GO:0017176

sp|Q9BRC7|PLCD4_HUMAN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
Search

PLCD4

0.61	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

0.85	GO:0007340	acrosome reaction
0.74	GO:0046488	phosphatidylinositol metabolic process
0.68	GO:0016042	lipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.49	GO:0043647	inositol phosphate metabolic process

0.80	GO:0004629	phospholipase C activity
0.66	GO:0005509	calcium ion binding
0.61	GO:0004871	signal transducer activity

0.67	GO:0005783	endoplasmic reticulum
0.59	GO:0031965	nuclear membrane
0.52	GO:0005829	cytosol
0.46	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.45	GO:0005886	plasma membrane
0.45	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|Q9BRD0|BUD13_HUMAN
BUD13 homolog
Search

BUD13

0.92	BUD13 homolog (Predicted)

0.43	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.42	GO:0051028	mRNA transport
0.42	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0006405	RNA export from nucleus
0.33	GO:0015992	proton transport
0.33	GO:0046034	ATP metabolic process

0.39	GO:0003723	RNA binding
0.39	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.38	GO:0043234	protein complex
0.37	GO:0044446	intracellular organelle part

sp|Q9BRF8|CPPED_HUMAN
Serine/threonine-protein phosphatase CPPED1
Search

CPPED1

0.95	Calcineurin like phosphoesterase domain containing 1

0.50

GO:0016787

hydrolase activity

0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.50

GO:0016787

sp|Q9BRG1|VPS25_HUMAN
Vacuolar protein-sorting-associated protein 25
Search

VPS25

0.91	WNK lysine deficient protein kinase 4

0.81	GO:0071985	multivesicular body sorting pathway
0.54	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.47	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.47	GO:0045324	late endosome to vacuole transport
0.47	GO:0072666	establishment of protein localization to vacuole
0.43	GO:0006886	intracellular protein transport
0.39	GO:0006468	protein phosphorylation
0.38	GO:0070294	renal sodium ion absorption
0.36	GO:0036258	multivesicular body assembly
0.35	GO:0006351	transcription, DNA-templated

0.53	GO:0047485	protein N-terminus binding
0.51	GO:0042803	protein homodimerization activity
0.41	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0005198	structural molecule activity
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding
0.35	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity
0.34	GO:0019869	chloride channel inhibitor activity

0.83	GO:0000814	ESCRT II complex
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.35	GO:0031515	tRNA (m1A) methyltransferase complex
0.34	GO:0005739	mitochondrion
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005923	bicellular tight junction

0.41

GO:0004674

sp|Q9BRG2|SH23A_HUMAN
SH2 domain-containing protein 3A
Search

SH2D3A

0.94	LOW QUALITY PROTEIN: SH2 domain-containing protein 3A

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.51	GO:0007254	JNK cascade
0.47	GO:0009967	positive regulation of signal transduction
0.36	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.51	GO:0005070	SH3/SH2 adaptor activity
0.36	GO:0004930	G-protein coupled receptor activity
0.36	GO:0005509	calcium ion binding

0.45	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BRH9|ZN251_HUMAN
Zinc finger protein 251
Search

0.82	LOW QUALITY PROTEIN: zinc finger protein 251

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0045321	leukocyte activation
0.34	GO:1901987	regulation of cell cycle phase transition
0.33	GO:0030154	cell differentiation
0.33	GO:0072707	cellular response to sodium dodecyl sulfate
0.33	GO:0007275	multicellular organism development
0.33	GO:0010948	negative regulation of cell cycle process

0.51	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.45	GO:0042802	identical protein binding
0.41	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003735	structural constituent of ribosome

0.43	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043228	non-membrane-bounded organelle
0.35	GO:0044422	organelle part
0.33	GO:1990904	ribonucleoprotein complex
0.32	GO:0043230	extracellular organelle
0.32	GO:0005615	extracellular space

sp|Q9BRI3|ZNT2_HUMAN
Zinc transporter 2
Search

SLC30A2

0.43	Cation diffusion facilitator family transporter

0.61	GO:0098655	cation transmembrane transport
0.59	GO:0006829	zinc II ion transport
0.58	GO:0006882	cellular zinc ion homeostasis
0.55	GO:0061088	regulation of sequestering of zinc ion
0.52	GO:0010043	response to zinc ion
0.48	GO:0098660	inorganic ion transmembrane transport
0.47	GO:0032846	positive regulation of homeostatic process
0.46	GO:0030073	insulin secretion
0.45	GO:0009749	response to glucose
0.44	GO:0051238	sequestering of metal ion

0.61	GO:0008324	cation transmembrane transporter activity
0.48	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.39	GO:0042803	protein homodimerization activity
0.37	GO:0015562	efflux transmembrane transporter activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0016874	ligase activity

0.50	GO:0031410	cytoplasmic vesicle
0.46	GO:0012505	endomembrane system
0.41	GO:0005886	plasma membrane
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0045177	apical part of cell
0.36	GO:0012506	vesicle membrane
0.36	GO:0044446	intracellular organelle part
0.33	GO:0098793	presynapse

0.35

GO:0016874

sp|Q9BRJ2|RM45_HUMAN
39S ribosomal protein L45, mitochondrial
Search

MRPL45

0.96	Mitochondrial ribosomal protein L45

0.38	GO:0070126	mitochondrial translational termination
0.37	GO:0070125	mitochondrial translational elongation

0.35	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.55	GO:0005840	ribosome
0.51	GO:0005739	mitochondrion
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.35	GO:0031975	envelope

sp|Q9BRJ6|CG050_HUMAN
Uncharacterized protein C7orf50
Search

0.55	GO:0003723	RNA binding
0.53	GO:0005515	protein binding

sp|Q9BRJ7|SDOS_HUMAN
Protein syndesmos
Search

0.97	Nudix (Nucleoside diphosphate linked moiety X)-type motif 16

0.58	GO:2000779	regulation of double-strand break repair
0.54	GO:0045738	negative regulation of DNA repair
0.50	GO:1901639	XDP catabolic process
0.49	GO:0046709	IDP catabolic process
0.49	GO:0016077	snoRNA catabolic process
0.46	GO:0045739	positive regulation of DNA repair
0.45	GO:0090068	positive regulation of cell cycle process
0.45	GO:0006382	adenosine to inosine editing
0.44	GO:0008284	positive regulation of cell proliferation
0.43	GO:0006402	mRNA catabolic process

0.57	GO:0030515	snoRNA binding
0.52	GO:0050072	m7G(5')pppN diphosphatase activity
0.50	GO:1901640	XTP binding
0.50	GO:1901641	ITP binding
0.47	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides
0.46	GO:0042803	protein homodimerization activity
0.44	GO:0050897	cobalt ion binding
0.43	GO:0003729	mRNA binding
0.43	GO:0008235	metalloexopeptidase activity
0.43	GO:0030145	manganese ion binding

0.46	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.35	GO:0005925	focal adhesion
0.33	GO:0005886	plasma membrane

0.52	EC:3.6.1.30	GO:0050072
0.42	KEGG:R03531	GO:0035870

sp|Q9BRJ9|MESP1_HUMAN
Mesoderm posterior protein 1
Search

MESP1

0.70	Mesoderm posterior bHLH transcription factor 1

0.63	GO:0001756	somitogenesis
0.62	GO:0007498	mesoderm development
0.61	GO:0007369	gastrulation
0.60	GO:0003210	cardiac atrium formation
0.60	GO:0060921	sinoatrial node cell differentiation
0.60	GO:0003259	cardioblast anterior-lateral migration
0.60	GO:0003235	sinus venosus development
0.60	GO:0035481	positive regulation of Notch signaling pathway involved in heart induction
0.59	GO:0070368	positive regulation of hepatocyte differentiation
0.59	GO:0045944	positive regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.62	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.60	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0035326	enhancer binding
0.45	GO:0003682	chromatin binding
0.34	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.32	GO:0004519	endonuclease activity
0.31	GO:0016491	oxidoreductase activity

0.49	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome

0.31

GO:0016491

sp|Q9BRK0|REEP2_HUMAN
Receptor expression-enhancing protein 2
Search

REEP2

0.71	Receptor expression-enhancing protein 2

0.61	GO:0032596	protein transport into membrane raft
0.60	GO:0071786	endoplasmic reticulum tubular network organization
0.59	GO:0050916	sensory perception of sweet taste
0.58	GO:0050913	sensory perception of bitter taste
0.56	GO:0032386	regulation of intracellular transport
0.37	GO:0051205	protein insertion into membrane
0.32	GO:0032259	methylation

0.62	GO:0031883	taste receptor binding
0.39	GO:0031849	olfactory receptor binding
0.37	GO:0008017	microtubule binding
0.32	GO:0008168	methyltransferase activity

0.56	GO:0005881	cytoplasmic microtubule
0.51	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005887	integral component of plasma membrane
0.39	GO:0070062	extracellular exosome
0.38	GO:0071782	endoplasmic reticulum tubular network
0.33	GO:0031966	mitochondrial membrane

0.32

GO:0008168

sp|Q9BRK3|MXRA8_HUMAN
Matrix remodeling-associated protein 8
Search

0.92	Matrix remodeling-associated protein 8

0.53	GO:0060857	establishment of glial blood-brain barrier
0.36	GO:0016055	Wnt signaling pathway
0.34	GO:0035556	intracellular signal transduction
0.33	GO:0016310	phosphorylation
0.30	GO:0044260	cellular macromolecule metabolic process
0.30	GO:0043412	macromolecule modification
0.30	GO:0006807	nitrogen compound metabolic process
0.30	GO:0044238	primary metabolic process

0.33

GO:0016301

kinase activity

0.47	GO:0009986	cell surface
0.32	GO:0005622	intracellular
0.30	GO:1903561	extracellular vesicle
0.30	GO:0044422	organelle part
0.30	GO:0012505	endomembrane system
0.30	GO:0044425	membrane part
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0005615	extracellular space

sp|Q9BRK4|LZTS2_HUMAN
Leucine zipper putative tumor suppressor 2
Search

LZTS2

0.95	Leucine zipper tumor suppressor 2

0.74	GO:0051255	spindle midzone assembly
0.72	GO:0030178	negative regulation of Wnt signaling pathway
0.71	GO:0051013	microtubule severing
0.68	GO:0016055	Wnt signaling pathway
0.65	GO:0051301	cell division
0.64	GO:0051168	nuclear export
0.60	GO:1900181	negative regulation of protein localization to nucleus
0.60	GO:0060828	regulation of canonical Wnt signaling pathway
0.58	GO:0001822	kidney development
0.57	GO:0008285	negative regulation of cell proliferation

0.43	GO:0008017	microtubule binding
0.40	GO:0008013	beta-catenin binding
0.34	GO:0003678	DNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0030496	midbody
0.66	GO:0005813	centrosome
0.64	GO:0005874	microtubule
0.53	GO:0031982	vesicle
0.50	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.34	GO:0014069	postsynaptic density
0.33	GO:0043198	dendritic shaft
0.33	GO:0043197	dendritic spine
0.33	GO:0044297	cell body

sp|Q9BRK5|CAB45_HUMAN
45 kDa calcium-binding protein
Search

SDF4

0.53	Stromal cell derived factor 4

0.54	GO:0045444	fat cell differentiation
0.44	GO:0002040	sprouting angiogenesis
0.39	GO:0009650	UV protection
0.39	GO:0070625	zymogen granule exocytosis
0.39	GO:0045471	response to ethanol
0.39	GO:0021549	cerebellum development

0.70	GO:0005509	calcium ion binding
0.36	GO:0042802	identical protein binding

0.58	GO:0005796	Golgi lumen
0.52	GO:0005770	late endosome
0.37	GO:0070062	extracellular exosome
0.36	GO:0032059	bleb
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BRL6|SRSF8_HUMAN
Serine/arginine-rich splicing factor 8
Search

0.82	Serine and arginine rich splicing factor 8

0.69	GO:0043484	regulation of RNA splicing
0.47	GO:0050873	brown fat cell differentiation
0.44	GO:0007005	mitochondrion organization
0.43	GO:2000507	positive regulation of energy homeostasis
0.43	GO:2001171	positive regulation of ATP biosynthetic process
0.42	GO:0014850	response to muscle activity
0.41	GO:0043524	negative regulation of neuron apoptotic process
0.41	GO:0010822	positive regulation of mitochondrion organization
0.41	GO:0051091	positive regulation of DNA binding transcription factor activity
0.40	GO:1901857	positive regulation of cellular respiration

0.59	GO:0003723	RNA binding
0.44	GO:0003712	transcription cofactor activity
0.43	GO:0008134	transcription factor binding
0.43	GO:0005102	receptor binding
0.41	GO:0031490	chromatin DNA binding
0.38	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0005080	protein kinase C binding
0.36	GO:0043565	sequence-specific DNA binding
0.36	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.49	GO:0016607	nuclear speck
0.45	GO:0005829	cytosol
0.40	GO:0005681	spliceosomal complex
0.37	GO:0035061	interchromatin granule
0.36	GO:0016605	PML body
0.36	GO:1990844	interfibrillar mitochondrion
0.36	GO:1990843	subsarcolemmal mitochondrion
0.35	GO:0097440	apical dendrite
0.35	GO:0005719	nuclear euchromatin
0.34	GO:0043025	neuronal cell body

0.32

GO:0016874

sp|Q9BRL7|SC22C_HUMAN
Vesicle-trafficking protein SEC22c
Search

SEC22C

0.97	SEC22 vesicle trafficking protein homolog C

0.48	GO:0048280	vesicle fusion with Golgi apparatus
0.46	GO:0006888	ER to Golgi vesicle-mediated transport
0.45	GO:0006887	exocytosis
0.36	GO:0015031	protein transport
0.33	GO:0045454	cell redox homeostasis

0.47	GO:0000149	SNARE binding
0.47	GO:0005484	SNAP receptor activity

0.47	GO:0031201	SNARE complex
0.37	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BRN9|TM2D3_HUMAN
TM2 domain-containing protein 3
Search

TM2D3

0.97	TM2 domain-containing protein 3

0.41	GO:0071897	DNA biosynthetic process
0.40	GO:0006281	DNA repair
0.36	GO:0006435	threonyl-tRNA aminoacylation
0.33	GO:0006468	protein phosphorylation

0.42	GO:0003684	damaged DNA binding
0.42	GO:0003887	DNA-directed DNA polymerase activity
0.36	GO:0004829	threonine-tRNA ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0019239	deaminase activity
0.33	GO:0004672	protein kinase activity

0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.42

EC:2.7.7.7

GO:0003887

sp|Q9BRP0|OVOL2_HUMAN
Transcription factor Ovo-like 2
Search

OVOL2

0.97	Ovo like transcriptional repressor 1

0.63	GO:2000647	negative regulation of stem cell proliferation
0.60	GO:0008544	epidermis development
0.59	GO:0060214	endocardium formation
0.59	GO:0001842	neural fold formation
0.58	GO:0045618	positive regulation of keratinocyte differentiation
0.58	GO:0060347	heart trabecula formation
0.58	GO:0001755	neural crest cell migration
0.57	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.57	GO:0048557	embryonic digestive tract morphogenesis
0.57	GO:0010837	regulation of keratinocyte proliferation

0.56	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.52	GO:0003682	chromatin binding
0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding

0.49

GO:0005634

nucleus

sp|Q9BRP1|PDD2L_HUMAN
Programmed cell death protein 2-like
Search

PDCD2L

0.43	Ubiquitin like modifier activating enzyme 2

0.41	GO:1902262	apoptotic process involved in blood vessel morphogenesis
0.37	GO:0019319	hexose biosynthetic process
0.37	GO:0006006	glucose metabolic process
0.37	GO:0006757	ATP generation from ADP
0.36	GO:0006090	pyruvate metabolic process
0.36	GO:0016052	carbohydrate catabolic process
0.36	GO:0019362	pyridine nucleotide metabolic process
0.36	GO:0007049	cell cycle
0.33	GO:0016925	protein sumoylation

0.38	GO:0004347	glucose-6-phosphate isomerase activity
0.33	GO:0019948	SUMO activating enzyme activity
0.32	GO:0016881	acid-amino acid ligase activity
0.32	GO:0016787	hydrolase activity

0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

EC:5.3.1.9

GO:0004347

sp|Q9BRP4|PAAF1_HUMAN
Proteasomal ATPase-associated factor 1
Search

PAAF1

0.97	Proteasomal ATPase-associated factor 1

0.37	GO:0016032	viral process
0.35	GO:0006468	protein phosphorylation
0.34	GO:0032259	methylation
0.33	GO:0006457	protein folding

0.38	GO:0016905	myosin heavy chain kinase activity
0.37	GO:0005515	protein binding
0.34	GO:0008168	methyltransferase activity
0.34	GO:0003723	RNA binding

0.72	GO:1905369	endopeptidase complex
0.58	GO:0043234	protein complex
0.44	GO:0044424	intracellular part
0.30	GO:0044425	membrane part

0.38

EC:2.7.11.7

GO:0016905

sp|Q9BRP7|FDXA1_HUMAN
Ferredoxin-fold anticodon-binding domain-containing protein 1
Search

FDXACB1

0.97	Ferredoxin-fold anticodon-binding domain-containing protein 1

0.65	GO:0006432	phenylalanyl-tRNA aminoacylation
0.40	GO:0097502	mannosylation
0.35	GO:0070475	rRNA base methylation

0.65	GO:0004826	phenylalanine-tRNA ligase activity
0.53	GO:0016757	transferase activity, transferring glycosyl groups
0.41	GO:0005212	structural constituent of eye lens
0.39	GO:0032555	purine ribonucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0008144	drug binding
0.38	GO:0005515	protein binding
0.37	GO:0003735	structural constituent of ribosome
0.37	GO:0070042	rRNA (uridine-N3-)-methyltransferase activity

0.68	GO:0009328	phenylalanine-tRNA ligase complex
0.56	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0015934	large ribosomal subunit
0.30	GO:0016021	integral component of membrane

0.65

EC:6.1.1.20

GO:0004826

sp|Q9BRP8|PYM1_HUMAN
Partner of Y14 and mago
Search

PYM1

0.95	PYM homolog 1, exon junction complex associated factor

0.86	GO:1903259	exon-exon junction complex disassembly
0.82	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.76	GO:0045727	positive regulation of translation

0.73	GO:0043022	ribosome binding
0.38	GO:0003723	RNA binding
0.37	GO:0005515	protein binding

0.85	GO:0035145	exon-exon junction complex
0.71	GO:0005730	nucleolus
0.70	GO:0030054	cell junction
0.64	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BRP9|YK016_HUMAN
Putative uncharacterized protein MGC13053
Search

sp|Q9BRQ0|PYGO2_HUMAN
Pygopus homolog 2
Search

PYGO2

0.94	Potassium calcium-activated channel subfamily N member 3

0.67	GO:0007289	spermatid nucleus differentiation
0.66	GO:0035563	positive regulation of chromatin binding
0.65	GO:0033599	regulation of mammary gland epithelial cell proliferation
0.63	GO:0001822	kidney development
0.63	GO:0051569	regulation of histone H3-K4 methylation
0.63	GO:0002088	lens development in camera-type eye
0.63	GO:0060021	palate development
0.62	GO:0035065	regulation of histone acetylation
0.62	GO:0060070	canonical Wnt signaling pathway
0.61	GO:0030879	mammary gland development

0.68	GO:0035034	histone acetyltransferase regulator activity
0.62	GO:0042393	histone binding
0.58	GO:0003682	chromatin binding
0.53	GO:0046872	metal ion binding
0.44	GO:0140034	methylation-dependent protein binding
0.38	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0003714	transcription corepressor activity
0.33	GO:0004631	phosphomevalonate kinase activity

0.64	GO:1990907	beta-catenin-TCF complex
0.35	GO:0005654	nucleoplasm
0.31	GO:0005737	cytoplasm

0.33	EC:2.7.4.2	GO:0004631
0.33	KEGG:R03245	GO:0004631

sp|Q9BRQ3|NUD22_HUMAN
Nucleoside diphosphate-linked moiety X motif 22
Search

NUDT22

0.94	Nucleoside diphosphate-linked moiety X motif 22

0.35	GO:0010469	regulation of receptor activity
0.35	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.35	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006508	proteolysis

0.51	GO:0016787	hydrolase activity
0.36	GO:0008201	heparin binding
0.35	GO:0005515	protein binding
0.35	GO:0030545	receptor regulator activity
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0016772	transferase activity, transferring phosphorus-containing groups

0.52	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.51

GO:0016787

sp|Q9BRQ4|CK070_HUMAN
Uncharacterized protein C11orf70
Search

0.56	GO:1905515	non-motile cilium assembly
0.56	GO:0031122	cytoplasmic microtubule organization
0.55	GO:0007052	mitotic spindle organization

0.57	GO:0097546	ciliary base
0.53	GO:0005813	centrosome
0.52	GO:0030496	midbody
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BRQ5|ORAI3_HUMAN
Protein orai-3
Search

ORAI3

0.85	Calcium release-activated calcium channel protein 1

0.76	GO:0002115	store-operated calcium entry
0.50	GO:0070588	calcium ion transmembrane transport
0.43	GO:0070509	calcium ion import
0.40	GO:0061180	mammary gland epithelium development

0.56

GO:0015279

store-operated calcium channel activity

0.42	GO:0016323	basolateral plasma membrane
0.39	GO:0005829	cytosol
0.37	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q9BRQ6|MIC25_HUMAN
MICOS complex subunit MIC25
Search

CHCHD6

0.66	MICOS complex subunit

0.53	GO:0042407	cristae formation
0.44	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:0008053	mitochondrial fusion
0.36	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0071526	semaphorin-plexin signaling pathway

0.37	GO:0019902	phosphatase binding
0.37	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0032947	protein complex scaffold activity
0.35	GO:0017154	semaphorin receptor activity

0.83	GO:0061617	MICOS complex
0.46	GO:0005829	cytosol
0.34	GO:0005634	nucleus

sp|Q9BRQ8|AIFM2_HUMAN
Apoptosis-inducing factor 2
Search

AIFM2

0.94	Apoptosis inducing factor, mitochondria associated 2

0.81	GO:0008637	apoptotic mitochondrial changes
0.74	GO:0043065	positive regulation of apoptotic process
0.64	GO:0022904	respiratory electron transport chain

0.81	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity
0.62	GO:0050660	flavin adenine dinucleotide binding
0.52	GO:0003677	DNA binding

0.77	GO:0005811	lipid droplet
0.73	GO:0005741	mitochondrial outer membrane
0.65	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.81

EC:1.5.5.1

GO:0004174

sp|Q9BRR0|ZKSC3_HUMAN
Zinc finger protein with KRAB and SCAN domains 3
Search

0.75	Zinc finger protein with KRAB and SCAN domains 3

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.45	GO:1902679	negative regulation of RNA biosynthetic process
0.44	GO:2000773	negative regulation of cellular senescence
0.42	GO:0007040	lysosome organization
0.40	GO:0010507	negative regulation of autophagy
0.40	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0007219	Notch signaling pathway

0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.42	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.39	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part

sp|Q9BRR3|TM246_HUMAN
Transmembrane protein 246
Search

TMEM246

0.51	Transmembrane domain-containing protein (Fragment)

0.30

GO:0044425

membrane part

sp|Q9BRR6|ADPGK_HUMAN
ADP-dependent glucokinase
Search

ADPGK

0.75	ADP-dependent glucokinase

0.60	GO:0005975	carbohydrate metabolic process
0.54	GO:0016310	phosphorylation
0.41	GO:0044281	small molecule metabolic process
0.36	GO:0072524	pyridine-containing compound metabolic process
0.36	GO:0006733	oxidoreduction coenzyme metabolic process
0.35	GO:1901575	organic substance catabolic process
0.35	GO:0072521	purine-containing compound metabolic process
0.35	GO:0019693	ribose phosphate metabolic process
0.35	GO:0006091	generation of precursor metabolites and energy
0.35	GO:0017144	drug metabolic process

0.62	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.56	GO:0016301	kinase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004563	beta-N-acetylhexosaminidase activity

0.49	GO:0005783	endoplasmic reticulum
0.36	GO:0005576	extracellular region
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.62

GO:0016773

sp|Q9BRR8|GPTC1_HUMAN
G patch domain-containing protein 1
Search

GPATCH1

0.75	G patch domain-containing protein 1

0.69	GO:0006397	mRNA processing
0.36	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.32	GO:0006629	lipid metabolic process
0.32	GO:0035556	intracellular signal transduction

0.51	GO:0003676	nucleic acid binding
0.32	GO:0004435	phosphatidylinositol phospholipase C activity
0.32	GO:0005509	calcium ion binding

0.48

GO:0071013

catalytic step 2 spliceosome

0.32	EC:3.1.4.11	GO:0004435
0.32	KEGG:R03435	GO:0004435

sp|Q9BRR9|RHG09_HUMAN
Rho GTPase-activating protein 9
Search

ARHGAP9

0.86	Rho-type GTPase-activating protein 9

0.73	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.38	GO:0008360	regulation of cell shape
0.38	GO:0043312	neutrophil degranulation
0.37	GO:0051056	regulation of small GTPase mediated signal transduction
0.33	GO:0006911	phagocytosis, engulfment
0.33	GO:0002011	morphogenesis of an epithelial sheet
0.32	GO:1902532	negative regulation of intracellular signal transduction
0.32	GO:0007015	actin filament organization

0.74	GO:0005096	GTPase activator activity
0.46	GO:0005543	phospholipid binding
0.35	GO:0005515	protein binding

0.38	GO:0034774	secretory granule lumen
0.36	GO:0005829	cytosol
0.35	GO:0005576	extracellular region
0.33	GO:0001891	phagocytic cup

sp|Q9BRS2|RIOK1_HUMAN
Serine/threonine-protein kinase RIO1
Search

RIOK1

0.70	Serine/threonine-protein kinase RIO1

0.63	GO:0006468	protein phosphorylation
0.59	GO:2000234	positive regulation of rRNA processing
0.53	GO:0030490	maturation of SSU-rRNA
0.33	GO:0098609	cell-cell adhesion
0.32	GO:0046854	phosphatidylinositol phosphorylation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016787	hydrolase activity

0.55	GO:0030688	preribosome, small subunit precursor
0.48	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.32	GO:0030054	cell junction
0.32	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004674

sp|Q9BRS8|LARP6_HUMAN
La-related protein 6
Search

LARP6

0.97	La ribonucleoprotein domain family member 6

0.71	GO:0006417	regulation of translation
0.64	GO:1902416	positive regulation of mRNA binding
0.63	GO:0010714	positive regulation of collagen metabolic process
0.63	GO:0032965	regulation of collagen biosynthetic process
0.60	GO:0006396	RNA processing
0.56	GO:0034250	positive regulation of cellular amide metabolic process
0.54	GO:0032270	positive regulation of cellular protein metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.53	GO:0010628	positive regulation of gene expression

0.64	GO:1990825	sequence-specific mRNA binding
0.63	GO:0035613	RNA stem-loop binding
0.60	GO:0017022	myosin binding
0.59	GO:0048027	mRNA 5'-UTR binding

0.59	GO:0005844	polysome
0.58	GO:0005634	nucleus
0.48	GO:0019013	viral nucleocapsid
0.33	GO:0005737	cytoplasm

sp|Q9BRT2|UQCC2_HUMAN
Ubiquinol-cytochrome-c reductase complex assembly factor 2
Search

UQCC2

0.97	Mitochondrial ubiquinol-cytochrome-c reductase complex assembly factor 2

0.83	GO:0017062	respiratory chain complex III assembly
0.83	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.80	GO:0033108	mitochondrial respiratory chain complex assembly
0.65	GO:0002082	regulation of oxidative phosphorylation
0.64	GO:2001014	regulation of skeletal muscle cell differentiation
0.63	GO:0070131	positive regulation of mitochondrial translation
0.61	GO:0050796	regulation of insulin secretion
0.59	GO:1903364	positive regulation of cellular protein catabolic process
0.40	GO:0032958	inositol phosphate biosynthetic process
0.36	GO:0016310	phosphorylation

0.36	GO:0016301	kinase activity
0.34	GO:0005515	protein binding
0.34	GO:0045134	uridine-diphosphatase activity
0.34	GO:0016776	phosphotransferase activity, phosphate group as acceptor

0.61	GO:0042645	mitochondrial nucleoid
0.58	GO:0005758	mitochondrial intermembrane space
0.57	GO:0016604	nuclear body
0.48	GO:0031966	mitochondrial membrane
0.48	GO:0019866	organelle inner membrane
0.34	GO:0097636	intrinsic component of autophagosome membrane
0.34	GO:0031166	integral component of vacuolar membrane
0.33	GO:0030173	integral component of Golgi membrane

0.34	EC:3.6.1.6	GO:0045134
0.34	KEGG:R00155	GO:0045134

sp|Q9BRT3|MIEN1_HUMAN
Migration and invasion enhancer 1
Search

MIEN1

0.97	Migration and invasion enhancer 1

0.53	GO:0051491	positive regulation of filopodium assembly
0.50	GO:0030335	positive regulation of cell migration
0.49	GO:0043066	negative regulation of apoptotic process
0.47	GO:0006915	apoptotic process

0.40

GO:0005515

protein binding

0.69	GO:0005829	cytosol
0.51	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.45	GO:0070062	extracellular exosome

sp|Q9BRT6|LLPH_HUMAN
Protein LLP homolog
Search

LLPH

0.97	LLP homolog, long-term synaptic facilitation

0.81	GO:0097484	dendrite extension
0.80	GO:0060999	positive regulation of dendritic spine development

0.76	GO:0001099	basal RNA polymerase II transcription machinery binding
0.38	GO:0003723	RNA binding

0.70	GO:0005730	nucleolus
0.64	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BRT7|CA097_HUMAN
Putative uncharacterized protein encoded by LINC00467
Search

sp|Q9BRT8|CBWD1_HUMAN
COBW domain-containing protein 1
Search

0.71	Cobalamin synthase W domain-containing protein 3

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding

sp|Q9BRT9|SLD5_HUMAN
DNA replication complex GINS protein SLD5
Search

GINS4

0.74	DNA replication complex GINS protein SLD5

0.69	GO:0006261	DNA-dependent DNA replication
0.58	GO:0001833	inner cell mass cell proliferation
0.50	GO:0000727	double-strand break repair via break-induced replication
0.45	GO:0032392	DNA geometric change
0.35	GO:0022616	DNA strand elongation

0.48	GO:0043138	3'-5' DNA helicase activity
0.35	GO:0005515	protein binding
0.34	GO:0003682	chromatin binding

0.60	GO:0005634	nucleus
0.46	GO:0005657	replication fork
0.46	GO:0032993	protein-DNA complex
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm

sp|Q9BRU2|TCAL7_HUMAN
Transcription elongation factor A protein-like 7
Search

TCEAL7

0.97	Transcription elongation factor A like 7

0.77	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.65	GO:0045892	negative regulation of transcription, DNA-templated
0.55	GO:0006414	translational elongation
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0006351	transcription, DNA-templated

0.59	GO:0050699	WW domain binding
0.56	GO:0003746	translation elongation factor activity

0.56

GO:0005634

nucleus

sp|Q9BRU9|UTP23_HUMAN
rRNA-processing protein UTP23 homolog
Search

UTP23

0.89	rRNA-binding ribosome biosynthesis protein UTP23

0.55

GO:0000480

endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.56	GO:0003730	mRNA 3'-UTR binding
0.55	GO:0048027	mRNA 5'-UTR binding
0.47	GO:0070181	small ribosomal subunit rRNA binding
0.34	GO:0005515	protein binding

0.78	GO:0032040	small-subunit processome
0.45	GO:0005730	nucleolus

sp|Q9BRV3|SWET1_HUMAN
Sugar transporter SWEET1
Search

SLC50A1

0.84	Sugar transporter SWEET

0.68	GO:0008643	carbohydrate transport
0.64	GO:0042946	glucoside transport
0.60	GO:0045815	positive regulation of gene expression, epigenetic
0.40	GO:0055085	transmembrane transport
0.37	GO:0048013	ephrin receptor signaling pathway

0.64	GO:0042947	glucoside transmembrane transporter activity
0.49	GO:0051119	sugar transmembrane transporter activity
0.38	GO:0046875	ephrin receptor binding

0.53	GO:0005794	Golgi apparatus
0.45	GO:0005886	plasma membrane
0.41	GO:0098588	bounding membrane of organelle
0.40	GO:0031984	organelle subcompartment
0.35	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q9BRV8|SIKE1_HUMAN
Suppressor of IKBKE 1
Search

SIKE1

0.94	Suppressor of IKK-epsilon protein A

0.55	GO:0042060	wound healing
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0007165	signal transduction

0.70	GO:0019901	protein kinase binding
0.69	GO:0017048	Rho GTPase binding
0.52	GO:0042803	protein homodimerization activity
0.35	GO:0003677	DNA binding
0.35	GO:0004713	protein tyrosine kinase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:2.7.10

GO:0004713

sp|Q9BRX2|PELO_HUMAN
Protein pelota homolog
Search

0.85	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay
0.84	GO:0070481	nuclear-transcribed mRNA catabolic process, non-stop decay
0.83	GO:0071025	RNA surveillance
0.61	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.56	GO:0060231	mesenchymal to epithelial transition
0.54	GO:0030513	positive regulation of BMP signaling pathway
0.54	GO:0007492	endoderm development
0.53	GO:0019827	stem cell population maintenance
0.51	GO:0008283	cell proliferation
0.46	GO:0032790	ribosome disassembly

0.63	GO:0004519	endonuclease activity
0.52	GO:0046872	metal ion binding
0.43	GO:0043022	ribosome binding
0.35	GO:0098639	collagen binding involved in cell-matrix adhesion
0.35	GO:0019903	protein phosphatase binding

0.58	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.35	GO:0034665	integrin alpha1-beta1 complex
0.35	GO:0045178	basal part of cell
0.35	GO:1990533	Dom34-Hbs1 complex
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0005925	focal adhesion

sp|Q9BRX5|PSF3_HUMAN
DNA replication complex GINS protein PSF3
Search

GINS3

0.86	DNA replication complex GINS protein PSF3

0.65	GO:0006260	DNA replication
0.45	GO:0007507	heart development
0.36	GO:0022616	DNA strand elongation
0.34	GO:1903047	mitotic cell cycle process
0.34	GO:0000727	double-strand break repair via break-induced replication

0.35	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.35	GO:0032993	protein-DNA complex
0.35	GO:0005694	chromosome
0.32	GO:0043234	protein complex

sp|Q9BRX8|F213A_HUMAN
Redox-regulatory protein FAM213A
Search

FAM213A

0.95	Selenoprotein U

0.61	GO:0045670	regulation of osteoclast differentiation
0.54	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process

0.54	GO:0016209	antioxidant activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.41	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.32

GO:0016491

sp|Q9BRX9|WDR83_HUMAN
WD repeat domain-containing protein 83
Search

WDR83

0.93	Mitogen-activated protein kinase organizer 1

0.72	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0016310	phosphorylation
0.36	GO:0035556	intracellular signal transduction
0.35	GO:0006464	cellular protein modification process

0.44	GO:0016301	kinase activity
0.36	GO:0005515	protein binding

0.78	GO:0071013	catalytic step 2 spliceosome
0.48	GO:0005737	cytoplasm
0.37	GO:0097708	intracellular vesicle
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0012505	endomembrane system

sp|Q9BRY0|S39A3_HUMAN
Zinc transporter ZIP3
Search

SLC39A3

0.96	Solute carrier family 39 (Zinc transporter), member 3

0.66	GO:0030001	metal ion transport
0.57	GO:0048701	embryonic cranial skeleton morphogenesis
0.56	GO:0060173	limb development
0.56	GO:0043029	T cell homeostasis
0.55	GO:0055085	transmembrane transport
0.53	GO:0001701	in utero embryonic development
0.53	GO:0072511	divalent inorganic cation transport
0.50	GO:0000902	cell morphogenesis
0.33	GO:0007165	signal transduction

0.69	GO:0046873	metal ion transmembrane transporter activity
0.56	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0005102	receptor binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005886	plasma membrane
0.32	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|Q9BRZ2|TRI56_HUMAN
E3 ubiquitin-protein ligase TRIM56
Search

TRIM56

0.80	Tripartite motif-containing protein 56

0.63	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9BS16|CENPK_HUMAN
Centromere protein K
Search

CENPK

0.97	Centromere protein K

0.37	GO:0034080	CENP-A containing nucleosome assembly
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0007062	sister chromatid cohesion
0.32	GO:0050808	synapse organization

0.35

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.40	GO:0000777	condensed chromosome kinetochore
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.32	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BS18|APC13_HUMAN
Anaphase-promoting complex subunit 13
Search

ANAPC13

0.97	Anaphase promoting complex subunit 13

0.85	GO:0070979	protein K11-linked ubiquitination
0.46	GO:0051301	cell division
0.46	GO:0007049	cell cycle

0.39

GO:0005515

protein binding

0.79

GO:0005680

anaphase-promoting complex

sp|Q9BS26|ERP44_HUMAN
Endoplasmic reticulum resident protein 44
Search

ERP44

0.96	Thioredoxin domain-containing 4

0.68	GO:0045454	cell redox homeostasis
0.55	GO:0034976	response to endoplasmic reticulum stress
0.54	GO:0006986	response to unfolded protein
0.50	GO:0009100	glycoprotein metabolic process
0.50	GO:0006457	protein folding
0.44	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.42	GO:0007507	heart development
0.35	GO:0043312	neutrophil degranulation

0.57	GO:0003756	protein disulfide isomerase activity
0.34	GO:0005515	protein binding

0.55	GO:0005788	endoplasmic reticulum lumen
0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.51	GO:0009986	cell surface
0.49	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0035580	specific granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.57

EC:5.3.4.1

GO:0003756

sp|Q9BS31|ZN649_HUMAN
Zinc finger protein 649
Search

0.84	RB associated KRAB zinc finger

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0006351	transcription, DNA-templated
0.34	GO:0043666	regulation of phosphoprotein phosphatase activity
0.33	GO:0006461	protein complex assembly
0.33	GO:0060443	mammary gland morphogenesis
0.32	GO:0048286	lung alveolus development

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding
0.34	GO:0019888	protein phosphatase regulator activity

0.45	GO:0005622	intracellular
0.39	GO:0043233	organelle lumen
0.39	GO:0043227	membrane-bounded organelle
0.39	GO:0017053	transcriptional repressor complex
0.35	GO:0043228	non-membrane-bounded organelle
0.30	GO:0005576	extracellular region

sp|Q9BS34|ZN670_HUMAN
Zinc finger protein 670
Search

0.73	Zinc finger protein 20

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0007165	signal transduction

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

0.44	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

EC:3.1.4.17

GO:0004114

sp|Q9BS40|LXN_HUMAN
Latexin
Search

LXN

0.97

Latexin

0.86	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.76	GO:0010951	negative regulation of endopeptidase activity
0.46	GO:0006954	inflammatory response

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.47	GO:0008201	heparin binding
0.37	GO:0005515	protein binding

0.44	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm

sp|Q9BS86|ZPBP1_HUMAN
Zona pellucida-binding protein 1
Search

ZPBP

0.97	LOW QUALITY PROTEIN: zona pellucida-binding protein 1

0.85	GO:0007339	binding of sperm to zona pellucida
0.41	GO:0001675	acrosome assembly

0.66	GO:0005576	extracellular region
0.46	GO:0001669	acrosomal vesicle
0.44	GO:0030667	secretory granule membrane
0.41	GO:0002199	zona pellucida receptor complex
0.39	GO:0044297	cell body
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BS91|S35A5_HUMAN
Probable UDP-sugar transporter protein SLC35A5
Search

SLC35A5

0.96	Probable UDP-sugar transporter protein SLC35A5

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport

0.79

GO:0005351

sugar:proton symporter activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

sp|Q9BS92|NPS3B_HUMAN
Protein NipSnap homolog 3B
Search

NIPSNAP3A

0.97	LOW QUALITY PROTEIN: protein NipSnap homolog 3A

0.42	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.41	GO:0007186	G-protein coupled receptor signaling pathway

0.42	GO:0004984	olfactory receptor activity
0.38	GO:0004930	G-protein coupled receptor activity
0.37	GO:0005515	protein binding

0.58	GO:0005739	mitochondrion
0.43	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q9BSA4|TTYH2_HUMAN
Protein tweety homolog 2
Search

sp|Q9BSA9|TM175_HUMAN
Endosomal/lysomomal potassium channel TMEM175
Search

TMEM175

0.97	Transmembrane protein 175

0.73	GO:0071805	potassium ion transmembrane transport
0.59	GO:0090385	phagosome-lysosome fusion
0.58	GO:0035751	regulation of lysosomal lumen pH

0.76	GO:0005267	potassium channel activity
0.60	GO:0022842	narrow pore channel activity

0.55	GO:0005764	lysosome
0.53	GO:0005768	endosome
0.30	GO:0016020	membrane

sp|Q9BSB4|ATGA1_HUMAN
Autophagy-related protein 101
Search

ATG101

0.96	Autophagy-related protein 101

0.77	GO:0006914	autophagy
0.60	GO:0007033	vacuole organization
0.55	GO:0070925	organelle assembly
0.36	GO:0016241	regulation of macroautophagy

0.55	GO:0032403	protein complex binding
0.54	GO:0042802	identical protein binding

0.62	GO:0000407	phagophore assembly site
0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol

sp|Q9BSC4|NOL10_HUMAN
Nucleolar protein 10
Search

NOL10

0.93	Nucleolar protein 10

0.34

GO:0003723

RNA binding

0.60	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BSD3|RHNO1_HUMAN
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1
Search

RHNO1

0.96	RAD9-HUS1-RAD1 interacting nuclear orphan 1

0.85	GO:0071479	cellular response to ionizing radiation
0.81	GO:0000077	DNA damage checkpoint
0.74	GO:0070318	positive regulation of G0 to G1 transition
0.67	GO:0034644	cellular response to UV
0.61	GO:0000725	recombinational repair
0.40	GO:0007049	cell cycle
0.39	GO:1901796	regulation of signal transduction by p53 class mediator
0.36	GO:0006260	DNA replication

0.36

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.56	GO:0005694	chromosome
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

sp|Q9BSD7|NTPCR_HUMAN
Cancer-related nucleoside-triphosphatase
Search

NTPCR

0.81	Nucleoside-triphosphatase

0.68	GO:0016311	dephosphorylation
0.34	GO:0016310	phosphorylation
0.33	GO:0000226	microtubule cytoskeleton organization

0.85	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides
0.35	GO:0017111	nucleoside-triphosphatase activity
0.35	GO:0016301	kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003723	RNA binding
0.33	GO:0008017	microtubule binding

0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.6.1.15

GO:0017111

sp|Q9BSE2|TMM79_HUMAN
Transmembrane protein 79
Search

TMEM79

0.97	Transmembrane protein 79

0.86	GO:0070268	cornification
0.86	GO:0061436	establishment of skin barrier
0.71	GO:0002070	epithelial cell maturation
0.70	GO:0031069	hair follicle morphogenesis
0.70	GO:0045684	positive regulation of epidermis development
0.68	GO:0042335	cuticle development
0.66	GO:0045055	regulated exocytosis

0.61

GO:0042802

identical protein binding

0.85	GO:0032588	trans-Golgi network membrane
0.66	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

sp|Q9BSE4|HERP2_HUMAN
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
Search

HERPUD2

0.91	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein-like

0.45	GO:0007283	spermatogenesis
0.45	GO:0006986	response to unfolded protein

0.30

GO:0044425

membrane part

sp|Q9BSE5|SPEB_HUMAN
Agmatinase, mitochondrial
Search

AGMAT

0.46	Agmatinase, mitochondrial

0.39	GO:0033388	putrescine biosynthetic process from arginine
0.38	GO:0008295	spermidine biosynthetic process
0.37	GO:0097055	agmatine biosynthetic process
0.33	GO:0006468	protein phosphorylation

0.74	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
0.54	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding

0.36	GO:0070062	extracellular exosome
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.74

EC:3.5.3

GO:0016813

sp|Q9BSF0|SMAKA_HUMAN
Small membrane A-kinase anchor protein
Search

0.93	Small membrane A-kinase anchor protein (Fragment)

0.50

GO:0016310

phosphorylation

0.85	GO:0034237	protein kinase A regulatory subunit binding
0.52	GO:0016301	kinase activity

0.45

GO:0005886

plasma membrane

sp|Q9BSF4|TIM29_HUMAN
Mitochondrial import inner membrane translocase subunit Tim29
Search

TIMM29

0.97	Translocase of inner mitochondrial membrane 29

0.65	GO:0045039	protein import into mitochondrial inner membrane
0.36	GO:0043044	ATP-dependent chromatin remodeling
0.35	GO:0006479	protein methylation
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0006518	peptide metabolic process
0.34	GO:0043604	amide biosynthetic process
0.33	GO:1901566	organonitrogen compound biosynthetic process
0.33	GO:0010467	gene expression

0.37	GO:0005515	protein binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0016887	ATPase activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0042721	mitochondrial inner membrane protein insertion complex
0.61	GO:0005758	mitochondrial intermembrane space
0.36	GO:0016514	SWI/SNF complex
0.34	GO:0005840	ribosome
0.33	GO:0016592	mediator complex
0.30	GO:0016021	integral component of membrane

0.34

EC:3.6.1.3

GO:0016887

sp|Q9BSF8|BTBDA_HUMAN
BTB/POZ domain-containing protein 10
Search

BTBD10

0.91	BTB/POZ domain-containing protein 10

0.84	GO:1901215	negative regulation of neuron death
0.77	GO:0042327	positive regulation of phosphorylation
0.67	GO:0044342	type B pancreatic cell proliferation

0.44

GO:0005515

protein binding

0.79	GO:0001650	fibrillar center
0.49	GO:0005737	cytoplasm

sp|Q9BSG0|PADC1_HUMAN
Protease-associated domain-containing protein 1
Search

PRADC1

0.97	Protease-associated domain-containing protein 1

0.55

GO:0006508

proteolysis

0.55	GO:0008233	peptidase activity
0.34	GO:0005515	protein binding
0.32	GO:0017171	serine hydrolase activity

0.52	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.55

GO:0008233

sp|Q9BSG1|ZNF2_HUMAN
Zinc finger protein 2
Search

ZNF2

0.62	Zinc finger protein 2

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.41	GO:0071157	negative regulation of cell cycle arrest
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0030335	positive regulation of cell migration
0.40	GO:0006351	transcription, DNA-templated
0.39	GO:0008285	negative regulation of cell proliferation
0.39	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043065	positive regulation of apoptotic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.30	GO:0005515	protein binding

0.44	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0005829	cytosol
0.38	GO:0015629	actin cytoskeleton
0.38	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BSG5|RTBDN_HUMAN
Retbindin
Search

RTBDN

0.97	LOW QUALITY PROTEIN: retbindin

0.47

GO:0048741

skeletal muscle fiber development

0.66

GO:1902444

riboflavin binding

0.76	GO:0033165	interphotoreceptor matrix
0.56	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BSH3|NICN1_HUMAN
Nicolin-1
Search

NICN1

0.97	Macrophage stimulating 1 receptor (C-met-related tyrosine kinase)

0.56	GO:0006546	glycine catabolic process
0.50	GO:0018095	protein polyglutamylation
0.49	GO:0032259	methylation
0.38	GO:0016310	phosphorylation

0.59	GO:0004047	aminomethyltransferase activity
0.45	GO:0008483	transaminase activity
0.38	GO:0016301	kinase activity

0.57	GO:0005874	microtubule
0.56	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion

0.59

EC:2.1.2.10

GO:0004047

sp|Q9BSH4|TACO1_HUMAN
Translational activator of cytochrome c oxidase 1
Search

TACO1

0.97	Translational activator of mitochondrially encoded cytochrome c oxidase I

0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0051171	regulation of nitrogen compound metabolic process
0.50	GO:0080090	regulation of primary metabolic process
0.50	GO:0010468	regulation of gene expression
0.49	GO:0097659	nucleic acid-templated transcription
0.46	GO:0010467	gene expression
0.46	GO:0034645	cellular macromolecule biosynthetic process

0.48	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.32	GO:0016779	nucleotidyltransferase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.50	GO:0005739	mitochondrion
0.49	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016779

sp|Q9BSH5|HDHD3_HUMAN
Haloacid dehalogenase-like hydrolase domain-containing protein 3
Search

HDHD3

0.95	Haloacid dehalogenase like hydrolase domain containing 3

0.33

GO:0016311

dephosphorylation

0.50	GO:0016787	hydrolase activity
0.34	GO:0005515	protein binding

0.49

GO:0005739

mitochondrion

0.50

GO:0016787

sp|Q9BSI4|TINF2_HUMAN
TERF1-interacting nuclear factor 2
Search

TINF2

0.97	TERF1-interacting nuclear factor 2

0.87	GO:0010836	negative regulation of protein ADP-ribosylation
0.87	GO:0032202	telomere assembly
0.86	GO:0070198	protein localization to chromosome, telomeric region
0.85	GO:0032211	negative regulation of telomere maintenance via telomerase
0.85	GO:0016233	telomere capping
0.84	GO:0050680	negative regulation of epithelial cell proliferation

0.82	GO:0042162	telomeric DNA binding
0.40	GO:0005515	protein binding

0.87	GO:0010370	perinucleolar chromocenter
0.86	GO:0070187	shelterin complex
0.78	GO:0016604	nuclear body
0.43	GO:0016363	nuclear matrix

sp|Q9BSJ1|TRI51_HUMAN
Tripartite motif-containing protein 51
Search

0.97	Tripartite motif-containing protein 51

0.34	GO:1903901	negative regulation of viral life cycle
0.33	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.33	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.33	GO:0010994	free ubiquitin chain polymerization
0.33	GO:0035458	cellular response to interferon-beta
0.33	GO:2000737	negative regulation of stem cell differentiation
0.33	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.33	GO:2000679	positive regulation of transcription regulatory region DNA binding
0.33	GO:0002230	positive regulation of defense response to virus by host
0.33	GO:0045069	regulation of viral genome replication

0.62	GO:0008270	zinc ion binding
0.36	GO:0019901	protein kinase binding
0.33	GO:0030674	protein binding, bridging
0.33	GO:0061630	ubiquitin protein ligase activity
0.32	GO:0008134	transcription factor binding

0.45	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q9BSJ2|GCP2_HUMAN
Gamma-tubulin complex component 2
Search

TUBGCP2

0.64	Gamma-tubulin complex component

0.81	GO:0007020	microtubule nucleation
0.48	GO:0090307	mitotic spindle assembly
0.48	GO:0051298	centrosome duplication
0.48	GO:0031122	cytoplasmic microtubule organization
0.46	GO:0051321	meiotic cell cycle
0.35	GO:0007229	integrin-mediated signaling pathway
0.33	GO:0006508	proteolysis

0.81	GO:0043015	gamma-tubulin binding
0.49	GO:0051011	microtubule minus-end binding
0.45	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0008237	metallopeptidase activity

0.79	GO:0000922	spindle pole
0.75	GO:0005815	microtubule organizing center
0.73	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.48	GO:0005654	nucleoplasm
0.47	GO:0032155	cell division site part
0.40	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q9BSJ5|CQ080_HUMAN
Uncharacterized protein C17orf80
Search

0.41	Putative conserved plasma membrane protein (Fragment)

0.30

GO:0044425

membrane part

sp|Q9BSJ6|FA64A_HUMAN
Protein FAM64A
Search

PIMREG

0.97	PICALM interacting mitotic regulator

0.73

GO:0005730

nucleolus

sp|Q9BSJ8|ESYT1_HUMAN
Extended synaptotagmin-1
Search

0.53	Extended synaptotagmin-1

0.82	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.72	GO:0006869	lipid transport
0.30	GO:0006687	glycosphingolipid metabolic process

0.70	GO:0008289	lipid binding
0.30	GO:0043167	ion binding
0.30	GO:0005515	protein binding

0.49	GO:0044232	organelle membrane contact site
0.47	GO:0031227	intrinsic component of endoplasmic reticulum membrane
0.30	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9BSK0|MALD1_HUMAN
MARVEL domain-containing protein 1
Search

MARVELD1

0.96	MARVEL domain-containing protein 1

0.68	GO:0001766	membrane raft polarization
0.63	GO:0042552	myelination
0.51	GO:0008104	protein localization
0.41	GO:0007049	cell cycle

0.67

GO:0019911

structural constituent of myelin sheath

0.61	GO:0045121	membrane raft
0.42	GO:0005856	cytoskeleton
0.39	GO:0005634	nucleus
0.38	GO:0005886	plasma membrane
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BSK1|ZN577_HUMAN
Zinc finger protein 577
Search

ZNF577

0.77	Zinc finger domain-containing protein (Fragment)

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0071157	negative regulation of cell cycle arrest
0.36	GO:0030335	positive regulation of cell migration
0.36	GO:0008285	negative regulation of cell proliferation
0.36	GO:0008284	positive regulation of cell proliferation
0.36	GO:0043065	positive regulation of apoptotic process
0.36	GO:0045597	positive regulation of cell differentiation

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.34	GO:0043228	non-membrane-bounded organelle

sp|Q9BSK2|S2533_HUMAN
Solute carrier family 25 member 33
Search

SLC25A33

0.97	Solute carrier family 25 (pyrimidine nucleotide carrier), member 33

0.60	GO:1990519	pyrimidine nucleotide import into mitochondrion
0.58	GO:1990314	cellular response to insulin-like growth factor stimulus
0.57	GO:0002082	regulation of oxidative phosphorylation
0.56	GO:0006390	mitochondrial transcription
0.56	GO:0031930	mitochondria-nucleus signaling pathway
0.55	GO:1903426	regulation of reactive oxygen species biosynthetic process
0.55	GO:0051881	regulation of mitochondrial membrane potential
0.55	GO:0071156	regulation of cell cycle arrest
0.54	GO:0032869	cellular response to insulin stimulus
0.54	GO:0030307	positive regulation of cell growth

0.57	GO:0015218	pyrimidine nucleotide transmembrane transporter activity
0.34	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.33	GO:0008168	methyltransferase activity

0.45	GO:0031967	organelle envelope
0.45	GO:0031090	organelle membrane
0.45	GO:0044429	mitochondrial part
0.35	GO:0012505	endomembrane system
0.35	GO:0044428	nuclear part
0.30	GO:0016021	integral component of membrane

0.34

EC:1.14.11

GO:0016706

sp|Q9BSK4|FEM1A_HUMAN
Protein fem-1 homolog A
Search

FEM1A

0.95	Fem-1 homolog A

0.82	GO:0050728	negative regulation of inflammatory response
0.56	GO:0051438	regulation of ubiquitin-protein transferase activity
0.52	GO:0016567	protein ubiquitination
0.47	GO:0043407	negative regulation of MAP kinase activity
0.42	GO:0043687	post-translational protein modification

0.87	GO:0031867	EP4 subtype prostaglandin E2 receptor binding
0.52	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0008134	transcription factor binding

0.44	GO:0005829	cytosol
0.41	GO:0005654	nucleoplasm

0.52

GO:0004842

sp|Q9BSL1|UBAC1_HUMAN
Ubiquitin-associated domain-containing protein 1
Search

UBAC1

0.96	UBA domain containing 1

0.72	GO:0005794	Golgi apparatus
0.69	GO:0005829	cytosol
0.56	GO:0005886	plasma membrane

sp|Q9BSM1|PCGF1_HUMAN
Polycomb group RING finger protein 1
Search

PCGF1

0.97	Polycomb group RING finger protein 1

0.83	GO:0036353	histone H2A-K119 monoubiquitination
0.55	GO:0045892	negative regulation of transcription, DNA-templated
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:0007568	aging
0.37	GO:0048589	developmental growth
0.35	GO:0070317	negative regulation of G0 to G1 transition

0.69	GO:0008022	protein C-terminus binding
0.48	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.39	GO:0046872	metal ion binding
0.34	GO:0019904	protein domain specific binding

0.82	GO:0031519	PcG protein complex
0.60	GO:0000152	nuclear ubiquitin ligase complex
0.59	GO:0005654	nucleoplasm

sp|Q9BSN7|TM204_HUMAN
Transmembrane protein 204
Search

TMEM204

0.97	Transmembrane protein 204

0.65	GO:0051145	smooth muscle cell differentiation
0.64	GO:0001945	lymph vessel development
0.64	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway

0.34

GO:0005515

protein binding

0.45	GO:0005886	plasma membrane
0.40	GO:0005912	adherens junction
0.30	GO:0044425	membrane part

sp|Q9BSQ5|CCM2_HUMAN
Cerebral cavernous malformations 2 protein
Search

CCM2

0.95	Cerebral cavernous malformation 2

0.84	GO:0001570	vasculogenesis
0.82	GO:0061154	endothelial tube morphogenesis
0.82	GO:0060837	blood vessel endothelial cell differentiation
0.82	GO:0048845	venous blood vessel morphogenesis
0.80	GO:0060039	pericardium development
0.79	GO:0045216	cell-cell junction organization
0.78	GO:0001885	endothelial cell development
0.77	GO:0035264	multicellular organism growth
0.75	GO:0048839	inner ear development
0.71	GO:0001701	in utero embryonic development

0.38

GO:0005515

protein binding

0.56	GO:0005739	mitochondrion
0.55	GO:0043234	protein complex

sp|Q9BSR8|YIPF4_HUMAN
Protein YIPF4
Search

0.18	Yip1 domain family member 4

0.72	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.56	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q9BST9|RTKN_HUMAN
Rhotekin
Search

RTKN

0.96

Rhotekin

0.84	GO:0007266	Rho protein signal transduction
0.83	GO:0032185	septin cytoskeleton organization
0.56	GO:0034260	negative regulation of GTPase activity
0.50	GO:0042981	regulation of apoptotic process
0.39	GO:0030097	hemopoiesis
0.38	GO:0006915	apoptotic process
0.33	GO:0008284	positive regulation of cell proliferation
0.33	GO:0016310	phosphorylation

0.85	GO:0017049	GTP-Rho binding
0.57	GO:0005095	GTPase inhibitor activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016301	kinase activity
0.31	GO:0003677	DNA binding

0.45	GO:0005622	intracellular
0.32	GO:0005886	plasma membrane
0.31	GO:0043227	membrane-bounded organelle

sp|Q9BSU1|CP070_HUMAN
UPF0183 protein C16orf70
Search

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:0043001	Golgi to plasma membrane protein transport

0.70	GO:0003713	transcription coactivator activity
0.52	GO:0035254	glutamate receptor binding
0.51	GO:0030165	PDZ domain binding
0.37	GO:0016787	hydrolase activity

0.55	GO:0005634	nucleus
0.51	GO:0030672	synaptic vesicle membrane
0.49	GO:0030425	dendrite
0.49	GO:0005802	trans-Golgi network
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016787

sp|Q9BSU3|NAA11_HUMAN
N-alpha-acetyltransferase 11
Search

NAA10

0.96	N-terminal acetyltransferase complex ARD1 subunit like protein A

0.57	GO:0006474	N-terminal protein amino acid acetylation
0.55	GO:2000719	negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric
0.54	GO:0030920	peptidyl-serine acetylation
0.51	GO:0018200	peptidyl-glutamic acid modification
0.50	GO:0018209	peptidyl-serine modification
0.49	GO:0006475	internal protein amino acid acetylation
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006323	DNA packaging
0.33	GO:0007165	signal transduction

0.67	GO:0008080	N-acetyltransferase activity
0.47	GO:0043022	ribosome binding
0.35	GO:0005515	protein binding
0.35	GO:0005096	GTPase activator activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0016301	kinase activity
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding

0.62	GO:0031415	NatA complex
0.49	GO:0005829	cytosol
0.46	GO:0005730	nucleolus
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0071339	MLL1 complex
0.36	GO:0048188	Set1C/COMPASS complex
0.30	GO:0016020	membrane

0.67

GO:0008080

sp|Q9BSV6|SEN34_HUMAN
tRNA-splicing endonuclease subunit Sen34
Search

TSEN34

0.77	tRNA splicing endonuclease subunit 34

0.85	GO:0000379	tRNA-type intron splice site recognition and cleavage
0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.36	GO:0006397	mRNA processing
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.33	GO:0002098	tRNA wobble uridine modification
0.33	GO:0009059	macromolecule biosynthetic process
0.32	GO:0043547	positive regulation of GTPase activity

0.84	GO:0000213	tRNA-intron endonuclease activity
0.59	GO:0016829	lyase activity
0.51	GO:0003676	nucleic acid binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding
0.32	GO:0005096	GTPase activator activity
0.31	GO:0046872	metal ion binding

0.83	GO:0000214	tRNA-intron endonuclease complex
0.37	GO:0005730	nucleolus
0.36	GO:0015935	small ribosomal subunit
0.35	GO:0005654	nucleoplasm
0.34	GO:0033588	Elongator holoenzyme complex
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:3.1.27.9

GO:0000213

sp|Q9BSW2|EFC4B_HUMAN
EF-hand calcium-binding domain-containing protein 4B
Search

CRACR2A

0.83	EF-hand calcium-binding domain-containing protein 4B

0.49	GO:0002115	store-operated calcium entry
0.49	GO:0032237	activation of store-operated calcium channel activity
0.43	GO:0002250	adaptive immune response
0.42	GO:0043312	neutrophil degranulation

0.70	GO:0005509	calcium ion binding
0.60	GO:0003924	GTPase activity
0.58	GO:0032550	purine ribonucleoside binding
0.58	GO:0019001	guanyl nucleotide binding
0.49	GO:0032555	purine ribonucleotide binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005515	protein binding

0.43	GO:0035580	specific granule lumen
0.37	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q9BSW7|SYT17_HUMAN
Synaptotagmin-17
Search

SYT17

0.97	Synaptotagmin XVII

0.77	GO:0006887	exocytosis
0.55	GO:1903861	positive regulation of dendrite extension
0.49	GO:0017158	regulation of calcium ion-dependent exocytosis
0.48	GO:0048489	synaptic vesicle transport
0.48	GO:0099504	synaptic vesicle cycle
0.48	GO:0099643	signal release from synapse
0.48	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.48	GO:0006906	vesicle fusion
0.46	GO:0006836	neurotransmitter transport
0.44	GO:0001505	regulation of neurotransmitter levels

0.48	GO:0019905	syntaxin binding
0.48	GO:0005544	calcium-dependent phospholipid binding
0.47	GO:0030276	clathrin binding
0.44	GO:0005509	calcium ion binding
0.35	GO:0017137	Rab GTPase binding

0.50	GO:0005802	trans-Golgi network
0.47	GO:0098793	presynapse
0.39	GO:0005886	plasma membrane
0.34	GO:0070382	exocytic vesicle
0.32	GO:0030141	secretory granule
0.32	GO:0030658	transport vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|Q9BSY4|CHCH5_HUMAN
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5
Search

CHCHD5

0.97	Coiled-coil-helix-coiled-coil-helix domain-containing protein 5

0.84	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.64	GO:0009060	aerobic respiration

0.79

GO:0005758

mitochondrial intermembrane space

sp|Q9BSY9|DESI2_HUMAN
Desumoylating isopeptidase 2
Search

DESI2

0.94	Desumoylating isopeptidase 2

0.56	GO:0060027	convergent extension involved in gastrulation
0.44	GO:0006508	proteolysis

0.44

GO:0008233

peptidase activity

0.47

GO:0005737

cytoplasm

0.44

GO:0008233

sp|Q9BT04|FUZZY_HUMAN
Protein fuzzy homolog
Search

FUZ

0.97	Fuzzy planar cell polarity protein

0.86	GO:0045724	positive regulation of cilium assembly
0.85	GO:0001843	neural tube closure
0.84	GO:1905515	non-motile cilium assembly
0.82	GO:0030336	negative regulation of cell migration
0.53	GO:2000314	negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
0.53	GO:0090301	negative regulation of neural crest formation
0.51	GO:0010172	embryonic body morphogenesis
0.50	GO:0001736	establishment of planar polarity
0.50	GO:0008589	regulation of smoothened signaling pathway
0.49	GO:0048704	embryonic skeletal system morphogenesis

0.37

GO:0005515

protein binding

0.44	GO:0070062	extracellular exosome
0.44	GO:0005856	cytoskeleton
0.44	GO:0042995	cell projection
0.37	GO:0005737	cytoplasm

sp|Q9BT09|CNPY3_HUMAN
Protein canopy homolog 3
Search

CNPY3

0.97	Trinucleotide repeat containing 5

0.52	GO:1903078	positive regulation of protein localization to plasma membrane
0.48	GO:0045087	innate immune response
0.39	GO:0002224	toll-like receptor signaling pathway

0.70	GO:0005102	receptor binding
0.34	GO:0046872	metal ion binding

0.45	GO:0005783	endoplasmic reticulum
0.39	GO:0071339	MLL1 complex
0.36	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q9BT17|MTG1_HUMAN
Mitochondrial ribosome-associated GTPase 1
Search

MTG1

0.83	Mitochondrial ribosome-associated GTPase 1

0.43	GO:0042254	ribosome biogenesis
0.41	GO:0044065	regulation of respiratory system process
0.40	GO:0070129	regulation of mitochondrial translation
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:1901304	regulation of spermidine biosynthetic process
0.33	GO:0046203	spermidine catabolic process
0.33	GO:0046208	spermine catabolic process
0.33	GO:0033240	positive regulation of cellular amine metabolic process
0.33	GO:0002098	tRNA wobble uridine modification
0.33	GO:0009447	putrescine catabolic process

0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0003924	GTPase activity
0.34	GO:0005515	protein binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0046592	polyamine oxidase activity

0.56	GO:0031966	mitochondrial membrane
0.56	GO:0019866	organelle inner membrane
0.41	GO:0005761	mitochondrial ribosome
0.33	GO:0033588	Elongator holoenzyme complex
0.33	GO:0031907	microbody lumen
0.32	GO:0044439	peroxisomal part
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0008138

sp|Q9BT22|ALG1_HUMAN
Chitobiosyldiphosphodolichol beta-mannosyltransferase
Search

ALG1

0.83	Chitobiosyldiphosphodolichol beta-mannosyltransferase

0.46	GO:0097502	mannosylation
0.44	GO:0043413	macromolecule glycosylation
0.44	GO:0009101	glycoprotein biosynthetic process
0.40	GO:0006464	cellular protein modification process
0.37	GO:0006488	dolichol-linked oligosaccharide biosynthetic process

0.65

GO:0016757

transferase activity, transferring glycosyl groups

0.43	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:2.4

GO:0016757

sp|Q9BT23|LIMD2_HUMAN
LIM domain-containing protein 2
Search

LIMD2

0.97	LIM domain-containing protein 2

0.55	GO:0051017	actin filament bundle assembly
0.54	GO:0030835	negative regulation of actin filament depolymerization
0.40	GO:0031529	ruffle organization
0.34	GO:0006468	protein phosphorylation

0.54	GO:0046872	metal ion binding
0.52	GO:0051015	actin filament binding
0.40	GO:0003785	actin monomer binding
0.39	GO:0045296	cadherin binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0097517	contractile actin filament bundle
0.40	GO:0097610	cell surface furrow
0.40	GO:0042641	actomyosin
0.40	GO:0005903	brush border
0.39	GO:0005925	focal adhesion
0.39	GO:0032155	cell division site part
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.35	GO:0005886	plasma membrane

sp|Q9BT25|HAUS8_HUMAN
HAUS augmin-like complex subunit 8
Search

HAUS8

0.97	HAUS augmin like complex subunit 8

0.82	GO:0007098	centrosome cycle
0.82	GO:0051225	spindle assembly
0.46	GO:0097711	ciliary basal body-plasma membrane docking
0.44	GO:0000086	G2/M transition of mitotic cell cycle
0.43	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.43	GO:0051301	cell division
0.38	GO:0010951	negative regulation of endopeptidase activity

0.38	GO:0005515	protein binding
0.38	GO:0004866	endopeptidase inhibitor activity

0.84	GO:0070652	HAUS complex
0.77	GO:0005813	centrosome
0.47	GO:0000922	spindle pole
0.45	GO:0005874	microtubule
0.40	GO:0005829	cytosol
0.38	GO:0005615	extracellular space

sp|Q9BT30|ALKB7_HUMAN
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial
Search

ALKBH7

0.63	Alpha-ketoglutarate-dependent dioxygenase alkB

0.86	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
0.64	GO:0006974	cellular response to DNA damage stimulus
0.54	GO:0010883	regulation of lipid storage
0.47	GO:0006631	fatty acid metabolic process
0.43	GO:0055114	oxidation-reduction process
0.34	GO:0033567	DNA replication, Okazaki fragment processing
0.33	GO:0006508	proteolysis
0.33	GO:0006400	tRNA modification
0.32	GO:0007155	cell adhesion

0.53	GO:0051213	dioxygenase activity
0.35	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0046872	metal ion binding
0.34	GO:0043142	single-stranded DNA-dependent ATPase activity
0.34	GO:0017108	5'-flap endonuclease activity
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004386	helicase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.75	GO:0005759	mitochondrial matrix
0.33	GO:0005581	collagen trimer
0.32	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.14

GO:0016705

sp|Q9BT40|INP5K_HUMAN
Inositol polyphosphate 5-phosphatase K
Search

INPP5K

0.96	Skeletal muscle-and kidney-enriched inositol phosphatase

0.80	GO:0046856	phosphatidylinositol dephosphorylation
0.63	GO:2001153	positive regulation of renal water transport
0.63	GO:2000466	negative regulation of glycogen (starch) synthase activity
0.62	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.61	GO:0090315	negative regulation of protein targeting to membrane
0.61	GO:0045719	negative regulation of glycogen biosynthetic process
0.61	GO:0035810	positive regulation of urine volume
0.60	GO:0043922	negative regulation by host of viral transcription
0.60	GO:0051497	negative regulation of stress fiber assembly
0.60	GO:0033137	negative regulation of peptidyl-serine phosphorylation

0.60	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
0.60	GO:0016312	inositol bisphosphate phosphatase activity
0.59	GO:0046030	inositol trisphosphate phosphatase activity
0.59	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
0.58	GO:0005000	vasopressin receptor activity
0.38	GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
0.36	GO:0005515	protein binding
0.36	GO:0042577	lipid phosphatase activity
0.36	GO:0003777	microtubule motor activity
0.34	GO:0005548	phospholipid transporter activity

0.58	GO:0032587	ruffle membrane
0.55	GO:0005802	trans-Golgi network
0.55	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0043005	neuron projection
0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.36	GO:0016459	myosin complex
0.33	GO:0048269	methionine adenosyltransferase complex

0.60	EC:3.1.3	GO:0016312
0.59	KEGG:R04404	GO:0004439

sp|Q9BT43|RPC7L_HUMAN
DNA-directed RNA polymerase III subunit RPC7-like
Search

POLR3GL

0.91	DNA-directed RNA polymerase III subunit G

0.80	GO:0006383	transcription by RNA polymerase III
0.46	GO:0032481	positive regulation of type I interferon production
0.46	GO:0032648	regulation of interferon-beta production
0.45	GO:0008283	cell proliferation
0.44	GO:0045089	positive regulation of innate immune response
0.35	GO:0045087	innate immune response
0.35	GO:0051607	defense response to virus
0.34	GO:0006359	regulation of transcription by RNA polymerase III
0.33	GO:0051028	mRNA transport
0.33	GO:0008380	RNA splicing

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.34	GO:0005515	protein binding
0.33	GO:0003729	mRNA binding
0.32	GO:0008270	zinc ion binding
0.31	GO:0016787	hydrolase activity

0.56	GO:0000790	nuclear chromatin
0.53	GO:0005666	DNA-directed RNA polymerase III complex
0.35	GO:0005829	cytosol
0.33	GO:0016607	nuclear speck
0.30	GO:0016021	integral component of membrane

0.70

EC:2.7.7.6

GO:0003899

sp|Q9BT49|THAP7_HUMAN
THAP domain-containing protein 7
Search

THAP7

0.97	THAP domain-containing protein 7

0.56	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0007017	microtubule-based process
0.40	GO:0007010	cytoskeleton organization
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0006313	transposition, DNA-mediated

0.68	GO:0070742	C2H2 zinc finger domain binding
0.64	GO:0047485	protein N-terminus binding
0.57	GO:0042802	identical protein binding
0.54	GO:0003677	DNA binding
0.41	GO:0005200	structural constituent of cytoskeleton
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding

0.61	GO:0016607	nuclear speck
0.60	GO:0031965	nuclear membrane
0.40	GO:0005874	microtubule
0.37	GO:0005694	chromosome
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BT56|SPXN_HUMAN
Spexin
Search

SPX

0.97	Spexin hormone

0.76	GO:0010469	regulation of receptor activity
0.70	GO:1904306	positive regulation of gastro-intestinal system smooth muscle contraction
0.47	GO:0035814	negative regulation of renal sodium excretion
0.46	GO:0003084	positive regulation of systemic arterial blood pressure
0.46	GO:0010459	negative regulation of heart rate
0.45	GO:0051930	regulation of sensory perception of pain
0.45	GO:0044539	long-chain fatty acid import
0.45	GO:0032099	negative regulation of appetite
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0016192	vesicle-mediated transport

0.85	GO:0005184	neuropeptide hormone activity
0.47	GO:0031766	type 3 galanin receptor binding
0.47	GO:0031765	type 2 galanin receptor binding

0.67	GO:0031045	dense core granule
0.57	GO:0005615	extracellular space
0.42	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

sp|Q9BT67|NFIP1_HUMAN
NEDD4 family-interacting protein 1
Search

NDFIP1

0.96	Nedd4 family interacting protein 1, like

0.79	GO:0007034	vacuolar transport
0.66	GO:0030001	metal ion transport
0.57	GO:0048294	negative regulation of isotype switching to IgE isotypes
0.57	GO:0032713	negative regulation of interleukin-4 production
0.56	GO:0032410	negative regulation of transporter activity
0.56	GO:0048302	regulation of isotype switching to IgG isotypes
0.56	GO:0002829	negative regulation of type 2 immune response
0.55	GO:0051224	negative regulation of protein transport
0.54	GO:0031398	positive regulation of protein ubiquitination
0.54	GO:0042130	negative regulation of T cell proliferation

0.48	GO:0050699	WW domain binding
0.41	GO:0004871	signal transducer activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0004521	endoribonuclease activity
0.33	GO:0016874	ligase activity
0.32	GO:0046872	metal ion binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005794	Golgi apparatus
0.50	GO:0005938	cell cortex
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.37	GO:0030425	dendrite
0.37	GO:0044440	endosomal part
0.37	GO:0045202	synapse
0.36	GO:0030054	cell junction
0.36	GO:0098805	whole membrane

0.33	EC:6	GO:0016874
0.33	KEGG:R03876	GO:0004842

sp|Q9BT73|PSMG3_HUMAN
Proteasome assembly chaperone 3
Search

PSMG3

0.97	Proteasome assembly chaperone 3

0.73	GO:1905369	endopeptidase complex
0.60	GO:0043234	protein complex
0.45	GO:0044424	intracellular part

sp|Q9BT76|UPK3B_HUMAN
Uroplakin-3b
Search

UPK3B

0.84	Uroplakin-3b

0.48	GO:0048519	negative regulation of biological process
0.42	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0046324	regulation of glucose import
0.39	GO:0016446	somatic hypermutation of immunoglobulin genes
0.38	GO:0070887	cellular response to chemical stimulus
0.38	GO:0051592	response to calcium ion
0.37	GO:0006950	response to stress
0.37	GO:0046578	regulation of Ras protein signal transduction
0.37	GO:0006366	transcription by RNA polymerase II
0.37	GO:0043547	positive regulation of GTPase activity

0.38	GO:0001055	RNA polymerase II activity
0.37	GO:0004601	peroxidase activity
0.37	GO:0003697	single-stranded DNA binding
0.37	GO:0005096	GTPase activator activity
0.37	GO:0005543	phospholipid binding
0.36	GO:0020037	heme binding
0.36	GO:0046983	protein dimerization activity
0.35	GO:0016887	ATPase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0016301	kinase activity

0.45	GO:0070062	extracellular exosome
0.39	GO:0032389	MutLalpha complex
0.38	GO:0005886	plasma membrane
0.37	GO:0005665	DNA-directed RNA polymerase II, core complex
0.30	GO:0016021	integral component of membrane

0.37	EC:1.11.1.7	GO:0004601
0.37	KEGG:R03532	GO:0004601

sp|Q9BT78|CSN4_HUMAN
COP9 signalosome complex subunit 4
Search

COPS4

0.88	COP9 constitutive photomorphogenic homolog subunit 4

0.47	GO:0000338	protein deneddylation
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.47	GO:0019784	NEDD8-specific protease activity
0.35	GO:0005515	protein binding

0.79	GO:0008180	COP9 signalosome
0.43	GO:0008021	synaptic vesicle
0.41	GO:0005829	cytosol
0.41	GO:0030054	cell junction
0.38	GO:0016607	nuclear speck
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q9BT81|SOX7_HUMAN
Transcription factor SOX-7
Search

SOX7

0.89	Transcription factor SOX-7

0.53	GO:0007369	gastrulation
0.52	GO:0007492	endoderm development
0.49	GO:0030111	regulation of Wnt signaling pathway
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0048646	anatomical structure formation involved in morphogenesis
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.45	GO:0042127	regulation of cell proliferation
0.45	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0045892	negative regulation of transcription, DNA-templated
0.44	GO:0072001	renal system development

0.55	GO:0003677	DNA binding
0.48	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0008013	beta-catenin binding
0.40	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0003713	transcription coactivator activity
0.39	GO:0046982	protein heterodimerization activity
0.39	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.38	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm

sp|Q9BT88|SYT11_HUMAN
Synaptotagmin-11
Search

SYT11

0.96	Synaptotagmin XI

0.61	GO:1905171	positive regulation of protein localization to phagocytic vesicle
0.61	GO:1990927	calcium ion regulated lysosome exocytosis
0.60	GO:1904468	negative regulation of tumor necrosis factor secretion
0.59	GO:1900165	negative regulation of interleukin-6 secretion
0.59	GO:0001778	plasma membrane repair
0.59	GO:0050765	negative regulation of phagocytosis
0.57	GO:1900424	regulation of defense response to bacterium
0.56	GO:0051289	protein homotetramerization
0.49	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.48	GO:0017158	regulation of calcium ion-dependent exocytosis

0.57	GO:0000149	SNARE binding
0.56	GO:0048487	beta-tubulin binding
0.55	GO:0031369	translation initiation factor binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042803	protein homodimerization activity
0.47	GO:0005544	calcium-dependent phospholipid binding
0.47	GO:0030276	clathrin binding
0.43	GO:0005509	calcium ion binding
0.34	GO:0001786	phosphatidylserine binding
0.33	GO:0046982	protein heterodimerization activity

0.59	GO:0032009	early phagosome
0.58	GO:0001891	phagocytic cup
0.55	GO:0055037	recycling endosome
0.54	GO:0097458	neuron part
0.53	GO:0005764	lysosome
0.51	GO:0120025	plasma membrane bounded cell projection
0.48	GO:0005887	integral component of plasma membrane
0.45	GO:0044456	synapse part
0.39	GO:0060077	inhibitory synapse
0.39	GO:0060076	excitatory synapse

sp|Q9BT92|TCHP_HUMAN
Trichoplein keratin filament-binding protein
Search

TCHP

0.96	Trichoplein keratin filament binding

0.67	GO:1902018	negative regulation of cilium assembly
0.62	GO:0030308	negative regulation of cell growth
0.59	GO:0006915	apoptotic process
0.39	GO:0030030	cell projection organization
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:0010468	regulation of gene expression

0.34	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity

0.77	GO:0005882	intermediate filament
0.65	GO:0097539	ciliary transition fiber
0.64	GO:0045179	apical cortex
0.64	GO:0030057	desmosome
0.59	GO:0005813	centrosome
0.53	GO:0005829	cytosol
0.49	GO:0005739	mitochondrion
0.46	GO:0005886	plasma membrane

sp|Q9BTA0|F167B_HUMAN
Protein FAM167B
Search

sp|Q9BTA9|WAC_HUMAN
WW domain-containing adapter protein with coiled-coil
Search

WAC

0.93	WW domain-containing adapter protein with coiled-coil

0.86	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination
0.85	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.85	GO:0044783	G1 DNA damage checkpoint
0.83	GO:0010390	histone monoubiquitination
0.83	GO:0016239	positive regulation of macroautophagy
0.72	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0009247	glycolipid biosynthetic process
0.39	GO:0006351	transcription, DNA-templated

0.84	GO:0000993	RNA polymerase II core binding
0.76	GO:0003682	chromatin binding
0.42	GO:0050694	galactose 3-O-sulfotransferase activity

0.67	GO:0005654	nucleoplasm
0.65	GO:0005681	spliceosomal complex
0.39	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0050694

sp|Q9BTC0|DIDO1_HUMAN
Death-inducer obliterator 1
Search

DIDO1

0.73	Death-inducer obliterator 1

0.82	GO:0097190	apoptotic signaling pathway
0.57	GO:0097659	nucleic acid-templated transcription
0.53	GO:0010467	gene expression
0.52	GO:0034645	cellular macromolecule biosynthetic process

0.52	GO:0046872	metal ion binding
0.37	GO:0003723	RNA binding

0.43	GO:0005819	spindle
0.39	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BTC8|MTA3_HUMAN
Metastasis-associated protein MTA3
Search

MTA3

0.87	Metastasis associated 1 family member 3

0.62	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.58	GO:0008284	positive regulation of cell proliferation
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:1902679	negative regulation of RNA biosynthetic process
0.51	GO:0060215	primitive hemopoiesis
0.39	GO:1902499	positive regulation of protein autoubiquitination
0.38	GO:0010212	response to ionizing radiation
0.37	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.77	GO:0003682	chromatin binding
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.60	GO:0003700	DNA binding transcription factor activity
0.56	GO:0032403	protein complex binding
0.38	GO:0001103	RNA polymerase II repressing transcription factor binding
0.38	GO:0001047	core promoter binding
0.37	GO:0003714	transcription corepressor activity
0.37	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.38	GO:0017053	transcriptional repressor complex
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0000785	chromatin
0.36	GO:0005874	microtubule
0.36	GO:1904949	ATPase complex
0.35	GO:0012505	endomembrane system
0.35	GO:0031967	organelle envelope

sp|Q9BTD1|SHAS3_HUMAN
Putative uncharacterized protein SHANK2-AS3
Search

sp|Q9BTD3|TM121_HUMAN
Transmembrane protein 121
Search

TMEM121

0.67	Transmembrane protein 121b

0.30

GO:0044425

membrane part

sp|Q9BTD8|RBM42_HUMAN
RNA-binding protein 42
Search

RBM42

0.95	RNA binding motif protein 42

0.58	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.36	GO:0007098	centrosome cycle
0.36	GO:0051225	spindle assembly
0.35	GO:0051568	histone H3-K4 methylation
0.34	GO:0009607	response to biotic stimulus
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0002088	lens development in camera-type eye

0.59	GO:0003723	RNA binding
0.35	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0005199	structural constituent of cell wall

0.38	GO:0005634	nucleus
0.36	GO:0070652	HAUS complex
0.35	GO:0034708	methyltransferase complex
0.35	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BTE0|NAT9_HUMAN
N-acetyltransferase 9
Search

NAT9

0.63	Ferredoxin reductase

0.33	GO:0006631	fatty acid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.67	GO:0008080	N-acetyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.32	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.34	GO:0043234	protein complex
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0008080

sp|Q9BTE1|DCTN5_HUMAN
Dynactin subunit 5
Search

DCTN5

0.83	Dynactin subunit 5

0.80	GO:0060976	coronary vasculature development
0.80	GO:0035904	aorta development
0.79	GO:0003281	ventricular septum development
0.41	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.39	GO:0006888	ER to Golgi vesicle-mediated transport

0.36

GO:0005515

protein binding

0.77	GO:0031965	nuclear membrane
0.77	GO:0005813	centrosome
0.68	GO:0005654	nucleoplasm
0.46	GO:0000777	condensed chromosome kinetochore
0.37	GO:0005829	cytosol

sp|Q9BTE3|MCMBP_HUMAN
Mini-chromosome maintenance complex-binding protein
Search

0.56	Putative conserved membrane protein (Fragment)

sp|Q9BTE6|AASD1_HUMAN
Alanyl-tRNA editing protein Aarsd1
Search

0.86	PTGES3L-AARSD1 readthrough

0.78

GO:0006419

alanyl-tRNA aminoacylation

0.78	GO:0004813	alanine-tRNA ligase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0003676	nucleic acid binding

0.78

EC:6.1.1.7

GO:0004813

sp|Q9BTE7|DCNL5_HUMAN
DCN1-like protein 5
Search

sp|Q9BTF0|THUM2_HUMAN
THUMP domain-containing protein 2
Search

THUMPD2

0.97	THUMP domain-containing protein 2

0.49

GO:0030488

tRNA methylation

0.59	GO:0003723	RNA binding
0.50	GO:0016423	tRNA (guanine) methyltransferase activity

0.30

GO:0031224

intrinsic component of membrane

0.50

GO:0016423

sp|Q9BTK2|YX002_HUMAN
Putative uncharacterized protein LOC642776
Search

sp|Q9BTK6|PAGR1_HUMAN
PAXIP1-associated glutamate-rich protein 1
Search

PAGR1

0.90	PTIP-associated protein 1

0.83	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.79	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0060717	chorion development
0.48	GO:0007420	brain development
0.48	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.47	GO:0071557	histone H3-K27 demethylation
0.46	GO:2001022	positive regulation of response to DNA damage stimulus
0.46	GO:1902749	regulation of cell cycle G2/M phase transition
0.43	GO:0006310	DNA recombination

0.81	GO:0030331	estrogen receptor binding
0.35	GO:0003676	nucleic acid binding

0.78	GO:0044666	MLL3/4 complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BTL3|RAM_HUMAN
RNMT-activating mini protein
Search

FAM103A1

0.96	RNMT-activating mini protein

0.63	GO:0032259	methylation
0.59	GO:0036031	recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex
0.47	GO:0009451	RNA modification
0.39	GO:0044260	cellular macromolecule metabolic process

0.59	GO:0003723	RNA binding
0.54	GO:0004482	mRNA (guanine-N7-)-methyltransferase activity
0.38	GO:0005515	protein binding

0.85	GO:0005845	mRNA cap binding complex
0.57	GO:0031533	mRNA cap methyltransferase complex
0.48	GO:0005654	nucleoplasm

0.54

EC:2.1.1.56

GO:0004482

sp|Q9BTL4|IER2_HUMAN
Immediate early response gene 2 protein
Search

IER2

0.97	Immediate early response 2

0.74	GO:0006366	transcription by RNA polymerase II
0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.70	GO:0048870	cell motility
0.49	GO:0071774	response to fibroblast growth factor
0.47	GO:0030182	neuron differentiation
0.36	GO:0070121	Kupffer's vesicle development
0.36	GO:0060026	convergent extension
0.36	GO:0007368	determination of left/right symmetry
0.35	GO:0060271	cilium assembly

0.79	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.76	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0005515	protein binding

0.69	GO:0005654	nucleoplasm
0.49	GO:0005737	cytoplasm

sp|Q9BTM1|H2AJ_HUMAN
Histone H2A.J
Search

sp|Q9BTM9|URM1_HUMAN
Ubiquitin-related modifier 1
Search

URM1

0.79	Ubiquitin-related modifier 1

0.79	GO:0034227	tRNA thio-modification
0.78	GO:0032447	protein urmylation
0.72	GO:0002098	tRNA wobble uridine modification
0.33	GO:0001403	invasive growth in response to glucose limitation
0.33	GO:0007114	cell budding
0.33	GO:0034599	cellular response to oxidative stress

0.46	GO:0016783	sulfurtransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0031386	protein tag

0.64	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome

0.46

EC:2.8.1

GO:0016783

sp|Q9BTN0|LRFN3_HUMAN
Leucine-rich repeat and fibronectin type-III domain-containing protein 3
Search

LRFN3

0.89	Leucine-rich repeat and fibronectin type-III domain-containing protein 3

0.50	GO:0007409	axonogenesis
0.39	GO:0007155	cell adhesion
0.34	GO:0007259	JAK-STAT cascade
0.34	GO:0050778	positive regulation of immune response
0.34	GO:0051607	defense response to virus
0.33	GO:0010469	regulation of receptor activity

0.34	GO:0005125	cytokine activity
0.33	GO:0003779	actin binding

0.55	GO:0009986	cell surface
0.48	GO:0005578	proteinaceous extracellular matrix
0.47	GO:0005615	extracellular space
0.42	GO:0042734	presynaptic membrane
0.42	GO:0045211	postsynaptic membrane
0.41	GO:0030054	cell junction
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon
0.37	GO:0014069	postsynaptic density
0.31	GO:0005622	intracellular

sp|Q9BTP6|ZBED2_HUMAN
Zinc finger BED domain-containing protein 2
Search

ZBED2

0.97	Zinc finger BED domain-containing protein 2

0.51	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.49	GO:0050821	protein stabilization
0.47	GO:0001933	negative regulation of protein phosphorylation
0.45	GO:1903955	positive regulation of protein targeting to mitochondrion

0.55	GO:0003677	DNA binding
0.35	GO:0046872	metal ion binding

sp|Q9BTP7|FAP24_HUMAN
Fanconi anemia core complex-associated protein 24
Search

FAAP24

0.97	Fanconi anemia-associated protein of

0.65

GO:0006281

DNA repair

0.56	GO:0003682	chromatin binding
0.35	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.85

GO:0043240

Fanconi anaemia nuclear complex

sp|Q9BTT0|AN32E_HUMAN
Acidic leucine-rich nuclear phosphoprotein 32 family member E
Search

ANP32E

0.94	Acidic leucine-rich nuclear phosphoprotein 32 family member E

0.82	GO:0043486	histone exchange
0.70	GO:0043086	negative regulation of catalytic activity
0.61	GO:0006334	nucleosome assembly
0.58	GO:0042981	regulation of apoptotic process
0.57	GO:0006913	nucleocytoplasmic transport
0.48	GO:0016569	covalent chromatin modification
0.34	GO:0007275	multicellular organism development
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.81	GO:0019212	phosphatase inhibitor activity
0.78	GO:0042393	histone binding
0.34	GO:0043565	sequence-specific DNA binding

0.80	GO:0000812	Swr1 complex
0.68	GO:0031410	cytoplasmic vesicle

sp|Q9BTT4|MED10_HUMAN
Mediator of RNA polymerase II transcription subunit 10
Search

MED10

0.94	Mediator of RNA polymerase II transcription subunit 10

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.52	GO:0019827	stem cell population maintenance
0.48	GO:1905072	cardiac jelly development
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0036302	atrioventricular canal development
0.36	GO:0016567	protein ubiquitination
0.34	GO:0016055	Wnt signaling pathway

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.37	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.50	GO:0070847	core mediator complex
0.37	GO:0000151	ubiquitin ligase complex

sp|Q9BTT6|LRRC1_HUMAN
Leucine-rich repeat-containing protein 1
Search

LRRC1

0.93	Leucine-rich repeat-containing protein 1

0.62	GO:0021747	cochlear nucleus development
0.62	GO:0016080	synaptic vesicle targeting
0.61	GO:0071896	protein localization to adherens junction
0.61	GO:0001921	positive regulation of receptor recycling
0.60	GO:0060088	auditory receptor cell stereocilium organization
0.60	GO:0060561	apoptotic process involved in morphogenesis
0.60	GO:0035089	establishment of apical/basal cell polarity
0.60	GO:0060603	mammary gland duct morphogenesis
0.59	GO:0048488	synaptic vesicle endocytosis
0.59	GO:0050918	positive chemotaxis

0.56	GO:0045296	cadherin binding
0.54	GO:0035255	ionotropic glutamate receptor binding
0.49	GO:0004385	guanylate kinase activity

0.62	GO:0034750	Scrib-APC-beta-catenin complex
0.61	GO:0035748	myelin sheath abaxonal region
0.59	GO:0005829	cytosol
0.59	GO:0042734	presynaptic membrane
0.58	GO:0044291	cell-cell contact zone
0.57	GO:0005913	cell-cell adherens junction
0.57	GO:0016323	basolateral plasma membrane
0.56	GO:0031252	cell leading edge
0.55	GO:0045211	postsynaptic membrane
0.52	GO:0008328	ionotropic glutamate receptor complex

0.49

EC:2.7.4.8

GO:0004385

sp|Q9BTU6|P4K2A_HUMAN
Phosphatidylinositol 4-kinase type 2-alpha
Search

PI4K2A

0.84	Phosphatidylinositol 4-kinase type 2 alpha

0.55	GO:0016310	phosphorylation
0.50	GO:0046488	phosphatidylinositol metabolic process
0.50	GO:0030258	lipid modification
0.49	GO:0007032	endosome organization
0.48	GO:0007030	Golgi organization
0.46	GO:0046474	glycerophospholipid biosynthetic process
0.41	GO:0002560	basophil mediated immunity
0.41	GO:0002276	basophil activation involved in immune response
0.39	GO:0043299	leukocyte degranulation

0.57	GO:0016301	kinase activity
0.53	GO:0035651	AP-3 adaptor complex binding
0.45	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0000287	magnesium ion binding

0.62	GO:0044221	host cell synapse
0.60	GO:0072556	other organism presynaptic membrane
0.58	GO:0042734	presynaptic membrane
0.56	GO:0043025	neuronal cell body
0.55	GO:0030425	dendrite
0.50	GO:0031083	BLOC-1 complex
0.49	GO:0098805	whole membrane
0.49	GO:0033644	host cell membrane
0.47	GO:0005802	trans-Golgi network
0.47	GO:0005764	lysosome

0.45

GO:0016773

sp|Q9BTV4|TMM43_HUMAN
Transmembrane protein 43
Search

TMEM43

0.97	Transmembrane protein 43

0.61

GO:0071763

nuclear membrane organization

0.57

GO:0043621

protein self-association

0.56	GO:0005637	nuclear inner membrane
0.56	GO:0044453	nuclear membrane part
0.56	GO:0005788	endoplasmic reticulum lumen
0.53	GO:0031301	integral component of organelle membrane
0.43	GO:0005794	Golgi apparatus

sp|Q9BTV5|FSD1_HUMAN
Fibronectin type III and SPRY domain-containing protein 1
Search

FSD1

0.97	Microtubule-associated protein GLFND

0.53	GO:0060236	regulation of mitotic spindle organization
0.53	GO:0031122	cytoplasmic microtubule organization
0.51	GO:0032465	regulation of cytokinesis
0.51	GO:0051260	protein homooligomerization
0.37	GO:0051301	cell division
0.37	GO:0007049	cell cycle

0.49	GO:0042803	protein homodimerization activity
0.49	GO:0008017	microtubule binding

0.51	GO:0005813	centrosome
0.49	GO:0005874	microtubule
0.41	GO:0097610	cell surface furrow
0.40	GO:0032155	cell division site part
0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BTV6|DPH7_HUMAN
Diphthine methyltransferase
Search

DPH7

0.91	diphthamide biosynthesis protein 7

0.82	GO:0017182	peptidyl-diphthamide metabolic process
0.82	GO:1900247	regulation of cytoplasmic translational elongation
0.48	GO:0044249	cellular biosynthetic process

sp|Q9BTV7|CABL2_HUMAN
CDK5 and ABL1 enzyme substrate 2
Search

CABLES2

0.89	Cdk5 and Abl enzyme substrate 2

0.72	GO:0051726	regulation of cell cycle
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.35

GO:0003735

structural constituent of ribosome

0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BTW9|TBCD_HUMAN
Tubulin-specific chaperone D
Search

TBCD

0.80	Tubulin folding cofactor D

0.84	GO:0007021	tubulin complex assembly
0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.76	GO:0043547	positive regulation of GTPase activity
0.74	GO:0031115	negative regulation of microtubule polymerization
0.68	GO:0007399	nervous system development
0.65	GO:0009653	anatomical structure morphogenesis
0.63	GO:0000278	mitotic cell cycle
0.63	GO:0048468	cell development
0.56	GO:0070830	bicellular tight junction assembly
0.56	GO:0034333	adherens junction assembly

0.84	GO:0048487	beta-tubulin binding
0.76	GO:0005096	GTPase activator activity

0.65	GO:0005813	centrosome
0.56	GO:0016328	lateral plasma membrane
0.54	GO:0005923	bicellular tight junction
0.53	GO:0005912	adherens junction
0.50	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BTX1|NDC1_HUMAN
Nucleoporin NDC1
Search

NDC1

0.94	NDC1 transmembrane nucleoporin

0.61	GO:0006999	nuclear pore organization
0.60	GO:0031081	nuclear pore distribution
0.59	GO:0046931	pore complex assembly
0.57	GO:0007129	synapsis
0.54	GO:0007283	spermatogenesis
0.53	GO:0070632	establishment of spindle pole body localization
0.53	GO:0071789	spindle pole body localization to nuclear envelope
0.51	GO:0043623	cellular protein complex assembly
0.51	GO:0030474	spindle pole body duplication
0.40	GO:0051028	mRNA transport

0.57

GO:0017056

structural constituent of nuclear pore

0.56	GO:0005643	nuclear pore
0.56	GO:0031965	nuclear membrane
0.52	GO:0015629	actin cytoskeleton
0.48	GO:0005816	spindle pole body
0.43	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.34	GO:0043657	host cell
0.30	GO:0016021	integral component of membrane

sp|Q9BTX3|TM208_HUMAN
Transmembrane protein 208
Search

TMEM208

0.48	LOW QUALITY PROTEIN: transmembrane protein 208

0.52	GO:0006624	vacuolar protein processing
0.40	GO:0006914	autophagy

0.47	GO:0005773	vacuole
0.39	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BTX7|TTPAL_HUMAN
Alpha-tocopherol transfer protein-like
Search

TTPAL

0.79	Alpha tocopherol transfer protein like

0.30

GO:0016020

membrane

sp|Q9BTY2|FUCO2_HUMAN
Plasma alpha-L-fucosidase
Search

FUCA2

0.91	Plasma alpha-L-fucosidase

0.79	GO:0006004	fucose metabolic process
0.58	GO:2000535	regulation of entry of bacterium into host cell
0.58	GO:0016139	glycoside catabolic process
0.52	GO:0009617	response to bacterium
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0043687	post-translational protein modification
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation

0.80	GO:0004560	alpha-L-fucosidase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.50	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0035578	azurophil granule lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

0.80

EC:3.2.1.51

GO:0004560

sp|Q9BTY7|HGH1_HUMAN
Protein HGH1 homolog
Search

HGH1

0.97	Brain protein 16

0.40	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.39	GO:0006367	transcription initiation from RNA polymerase II promoter
0.38	GO:0055085	transmembrane transport

0.42	GO:0003677	DNA binding
0.38	GO:0016746	transferase activity, transferring acyl groups

0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38

EC:2.3

GO:0016746

sp|Q9BTZ2|DHRS4_HUMAN
Dehydrogenase/reductase SDR family member 4
Search

0.86	NADH-dependent retinal reductase

0.52	GO:0055114	oxidation-reduction process
0.51	GO:0042574	retinal metabolic process
0.47	GO:0043011	myeloid dendritic cell differentiation
0.44	GO:0043066	negative regulation of apoptotic process
0.43	GO:0034599	cellular response to oxidative stress
0.41	GO:0009636	response to toxic substance
0.40	GO:0051262	protein tetramerization
0.40	GO:0008202	steroid metabolic process
0.39	GO:0006066	alcohol metabolic process
0.39	GO:0042180	cellular ketone metabolic process

0.53	GO:0016491	oxidoreductase activity
0.39	GO:0005102	receptor binding
0.34	GO:0042802	identical protein binding

0.49	GO:0042579	microbody
0.45	GO:0005739	mitochondrion
0.43	GO:0005635	nuclear envelope
0.39	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0070062	extracellular exosome
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0016491

sp|Q9BU02|THTPA_HUMAN
Thiamine-triphosphatase
Search

THTPA

0.97	Thiamine-triphosphatase

0.73	GO:0006772	thiamine metabolic process
0.62	GO:0042357	thiamine diphosphate metabolic process
0.57	GO:0016311	dephosphorylation
0.35	GO:0006091	generation of precursor metabolites and energy

0.88	GO:0050333	thiamin-triphosphatase activity
0.55	GO:0000287	magnesium ion binding

0.46

GO:0005737

cytoplasm

0.88	EC:3.6.1.28	GO:0050333
0.88	KEGG:R00618	GO:0050333

sp|Q9BU19|ZN692_HUMAN
Zinc finger protein 692
Search

ZNF692

0.94	Zinc finger domain-containing protein (Fragment)

0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.35	GO:0070534	protein K63-linked ubiquitination
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0040007	growth
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0016310	phosphorylation

0.57	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0016874	ligase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0016301	kinase activity

0.51	GO:0005730	nucleolus
0.32	GO:0005737	cytoplasm

0.41	EC:6	GO:0016874
0.34	KEGG:R03876	GO:0004842

sp|Q9BU20|RSG1_HUMAN
REM2- and Rab-like small GTPase 1
Search

RSG1

0.97	REM2 and RAB like small GTPase 1

0.43	GO:0031338	regulation of vesicle fusion
0.42	GO:0017157	regulation of exocytosis
0.41	GO:0060271	cilium assembly
0.41	GO:0006887	exocytosis
0.39	GO:0034613	cellular protein localization
0.38	GO:0015031	protein transport
0.35	GO:0001843	neural tube closure
0.34	GO:0016567	protein ubiquitination

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005515	protein binding

0.54	GO:0005654	nucleoplasm
0.42	GO:0036064	ciliary basal body
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BU23|LMF2_HUMAN
Lipase maturation factor 2
Search

LMF2

0.78	Lipase maturation factor

0.45

GO:0051604

protein maturation

0.34

GO:0005515

protein binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9BU40|CRDL1_HUMAN
Chordin-like protein 1
Search

CHRDL1

0.95	Chordin-like protein 1 isoform B

0.76	GO:0048749	compound eye development
0.70	GO:0030514	negative regulation of BMP signaling pathway
0.60	GO:0001503	ossification
0.55	GO:0007399	nervous system development
0.53	GO:0030154	cell differentiation
0.49	GO:0030509	BMP signaling pathway
0.47	GO:0043687	post-translational protein modification

0.53	GO:0005576	extracellular region
0.48	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|Q9BU61|NDUF3_HUMAN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
Search

NDUFAF3

0.95	NADH:ubiquinone oxidoreductase complex assembly factor 3

0.84

GO:0032981

mitochondrial respiratory chain complex I assembly

0.34

GO:0005515

protein binding

0.50	GO:0031966	mitochondrial membrane
0.50	GO:0019866	organelle inner membrane
0.50	GO:0005634	nucleus

sp|Q9BU64|CENPO_HUMAN
Centromere protein O
Search

CENPO

0.97	Centromere protein O

0.83	GO:0034508	centromere complex assembly
0.39	GO:0031055	chromatin remodeling at centromere
0.39	GO:0061641	CENP-A containing chromatin organization
0.39	GO:0006336	DNA replication-independent nucleosome assembly
0.39	GO:0043486	histone exchange
0.38	GO:0007062	sister chromatid cohesion

0.35

GO:0005515

protein binding

0.78	GO:0000776	kinetochore
0.42	GO:0000779	condensed chromosome, centromeric region
0.39	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen

sp|Q9BU68|PR15L_HUMAN
Proline-rich protein 15-like protein
Search

PRR15L

0.97	Testicular tissue protein Li 157

0.48

GO:0015031

protein transport

0.30

GO:0016021

integral component of membrane

sp|Q9BU70|TRMO_HUMAN
tRNA (adenine(37)-N6)-methyltransferase
Search

TRMO

0.72	tRNA methyltransferase O

0.73

GO:0030488

tRNA methylation

0.84	GO:0016430	tRNA (adenine-N6-)-methyltransferase activity
0.39	GO:0003723	RNA binding

0.84

EC:2.1.1.55

GO:0016430

sp|Q9BU76|MMTA2_HUMAN
Multiple myeloma tumor-associated protein 2
Search

0.90	Multiple myeloma tumor-associated protein 2

0.51	GO:0043312	neutrophil degranulation
0.50	GO:0016310	phosphorylation

0.52	GO:0016301	kinase activity
0.44	GO:0003723	RNA binding
0.42	GO:0005515	protein binding
0.35	GO:0003735	structural constituent of ribosome

0.52	GO:1904813	ficolin-1-rich granule lumen
0.51	GO:0034774	secretory granule lumen
0.43	GO:0005576	extracellular region
0.38	GO:0005762	mitochondrial large ribosomal subunit
0.30	GO:0016020	membrane

sp|Q9BU79|TM243_HUMAN
Transmembrane protein 243
Search

TMEM243

0.97	Transmembrane protein 243, mitochondrial a

0.30

GO:0044425

membrane part

sp|Q9BU89|DOHH_HUMAN
Deoxyhypusine hydroxylase
Search

DOHH

0.67	Deoxyhypusine hydroxylase

0.82	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0016049	cell growth
0.49	GO:0008283	cell proliferation
0.49	GO:0010508	positive regulation of autophagy

0.85	GO:0019135	deoxyhypusine monooxygenase activity
0.52	GO:0046872	metal ion binding
0.30	GO:0005515	protein binding

0.53	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005829	cytosol

0.85

EC:1.14.99.29

GO:0019135

sp|Q9BUA3|CK084_HUMAN
Uncharacterized protein C11orf84
Search

0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.38	GO:0030010	establishment of cell polarity
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0000226	microtubule cytoskeleton organization
0.36	GO:0006468	protein phosphorylation

0.37	GO:0005515	protein binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.37