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Queries 12001 to 13000

Query headerGNDescription
Estimated PPV, description
Biological process
Estimated PPV, GO-id, description
Molecular function
Estimated PPV, GO-i d, description
Cellular component
Estimated PPV, GO-id, description
Inverse ec2go, kegg2go
sp|Q7Z449|CP2U1_HUMAN
Cytochrome P450 2U1
Search
CYP2U1
0.97Cytochrome P450 family 2 subfamily U member 1
0.53GO:0055114oxidation-reduction process
0.35GO:0042572retinol metabolic process
0.34GO:0006805xenobiotic metabolic process
0.34GO:0008202steroid metabolic process
0.77GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63GO:0020037heme binding
0.63GO:0005506iron ion binding
0.52GO:0008395steroid hydroxylase activity
0.30GO:0044425membrane part
0.77EC:1.14.14 GO:0016712
sp|Q7Z460|CLAP1_HUMAN
CLIP-associating protein 1
Search
CLASP1
0.84Cytoplasmic linker associated protein 1
0.71GO:1903690negative regulation of wound healing, spreading of epidermal cells
0.71GO:1904259regulation of basement membrane assembly involved in embryonic body morphogenesis
0.70GO:0090091positive regulation of extracellular matrix disassembly
0.70GO:1901203positive regulation of extracellular matrix assembly
0.69GO:0030953astral microtubule organization
0.69GO:0051497negative regulation of stress fiber assembly
0.68GO:0010458exit from mitosis
0.68GO:0007026negative regulation of microtubule depolymerization
0.67GO:0040019positive regulation of embryonic development
0.67GO:0010470regulation of gastrulation
0.85GO:0043515kinetochore binding
0.85GO:0051010microtubule plus-end binding
0.68GO:0002162dystroglycan binding
0.85GO:0005828kinetochore microtubule
0.84GO:0005881cytoplasmic microtubule
0.72GO:0031592centrosomal corona
0.69GO:0045180basal cortex
0.68GO:0030981cortical microtubule cytoskeleton
0.64GO:0005925focal adhesion
0.61GO:0000776kinetochore
0.57GO:0005794Golgi apparatus
0.45GO:0070062extracellular exosome
0.30GO:0016020membrane
sp|Q7Z465|BNIPL_HUMAN
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein
Search
BNIPL
0.94BCL2 interacting protein like
0.76GO:0040009regulation of growth rate
0.70GO:0006915apoptotic process
0.68GO:0008285negative regulation of cell proliferation
0.53GO:0051057positive regulation of small GTPase mediated signal transduction
0.53GO:0001824blastocyst development
0.52GO:0007098centrosome cycle
0.52GO:0051146striated muscle cell differentiation
0.52GO:0045666positive regulation of neuron differentiation
0.51GO:0043410positive regulation of MAPK cascade
0.33GO:0051149positive regulation of muscle cell differentiation
0.67GO:0042802identical protein binding
0.34GO:0016462pyrophosphatase activity
0.33GO:0032550purine ribonucleoside binding
0.33GO:0032561guanyl ribonucleotide binding
0.33GO:0005096GTPase activator activity
0.32GO:0005509calcium ion binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.62GO:0005829cytosol
0.55GO:0031616spindle pole centrosome
0.54GO:0005634nucleus
0.52GO:0005814centriole
0.34GO:0012505endomembrane system
0.34GO:0048471perinuclear region of cytoplasm
0.34GO:0031967organelle envelope
0.30GO:0016020membrane
0.34EC:3.6.1 GO:0016462
sp|Q7Z478|DHX29_HUMAN
ATP-dependent RNA helicase DHX29
Search
DHX29
0.97ATP-dependent RNA helicase DHX29
0.74GO:0045948positive regulation of translational initiation
0.67GO:0006413translational initiation
0.43GO:0006396RNA processing
0.72GO:0004004ATP-dependent RNA helicase activity
0.66GO:0003743translation initiation factor activity
0.61GO:0043024ribosomal small subunit binding
0.57GO:0045296cadherin binding
0.53GO:0032559adenyl ribonucleotide binding
0.52GO:0008144drug binding
0.52GO:0035639purine ribonucleoside triphosphate binding
0.56GO:0016282eukaryotic 43S preinitiation complex
0.47GO:0005739mitochondrion
0.30GO:0016020membrane
sp|Q7Z494|NPHP3_HUMAN
Nephrocystin-3
Search
NPHP3
0.86Nephronophthisis 3
0.83GO:0071909determination of stomach left/right asymmetry
0.82GO:0071908determination of intestine left/right asymmetry
0.81GO:0060026convergent extension
0.80GO:0003143embryonic heart tube morphogenesis
0.80GO:0061371determination of heart left/right asymmetry
0.79GO:0048496maintenance of animal organ identity
0.78GO:0035469determination of pancreatic left/right asymmetry
0.78GO:0071910determination of liver left/right asymmetry
0.78GO:0072189ureter development
0.77GO:0001822kidney development
0.47GO:0003777microtubule motor activity
0.36GO:0005515protein binding
0.70GO:0097543ciliary inversin compartment
0.66GO:0097546ciliary base
0.50GO:0005871kinesin complex
0.37GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q7Z4B0|CR020_HUMAN
Putative uncharacterized protein encoded by LINC00305
Search
sp|Q7Z4F1|LRP10_HUMAN
Low-density lipoprotein receptor-related protein 10
Search
LRP10
0.94LDL receptor related protein 10
0.72GO:0048839inner ear development
0.65GO:0006869lipid transport
0.64GO:0006898receptor-mediated endocytosis
0.56GO:0006629lipid metabolic process
0.54GO:0001764neuron migration
0.52GO:0031175neuron projection development
0.79GO:0005041low-density lipoprotein receptor activity
0.46GO:0005887integral component of plasma membrane
sp|Q7Z4G1|COMD6_HUMAN
COMM domain-containing protein 6
Search
COMMD6
0.96COMM domain-containing protein 6
0.81GO:0032088negative regulation of NF-kappaB transcription factor activity
0.44GO:0097659nucleic acid-templated transcription
0.42GO:0010467gene expression
0.42GO:0034645cellular macromolecule biosynthetic process
0.41GO:0043547positive regulation of GTPase activity
0.84GO:0051059NF-kappaB binding
0.41GO:0005096GTPase activator activity
0.46GO:0005634nucleus
0.40GO:0005737cytoplasm
sp|Q7Z4G4|TRM11_HUMAN
tRNA (guanine(10)-N2)-methyltransferase homolog
Search
TRMT11
0.93tRNA methyltransferase 11 homolog
0.61GO:0032259methylation
0.39GO:0008033tRNA processing
0.36GO:0009451RNA modification
0.35GO:0051382kinetochore assembly
0.34GO:0000278mitotic cell cycle
0.33GO:0044260cellular macromolecule metabolic process
0.62GO:0008168methyltransferase activity
0.50GO:0003676nucleic acid binding
0.36GO:0140101catalytic activity, acting on a tRNA
0.34GO:0046982protein heterodimerization activity
0.30GO:0031224intrinsic component of membrane
0.62EC:2.1.1 GO:0008168
sp|Q7Z4H3|HDDC2_HUMAN
HD domain-containing protein 2
Search
HDDC2
0.94HD domain-containing protein 2
0.36GO:0005515protein binding
0.36GO:0016787hydrolase activity
0.59GO:0005739mitochondrion
0.43GO:0070062extracellular exosome
0.36EC:3 GO:0016787
sp|Q7Z4H4|ADM2_HUMAN
ADM2
Search
ADM2
0.97Adrenomedullin 2
0.75GO:0010469regulation of receptor activity
0.57GO:0045766positive regulation of angiogenesis
0.56GO:0001525angiogenesis
0.51GO:0010628positive regulation of gene expression
0.47GO:0006468protein phosphorylation
0.45GO:0045776negative regulation of blood pressure
0.44GO:0007189adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.44GO:0007631feeding behavior
0.44GO:0007586digestion
0.37GO:0019310inositol catabolic process
0.79GO:0005179hormone activity
0.53GO:0032403protein complex binding
0.37GO:0050113inositol oxygenase activity
0.34GO:0005506iron ion binding
0.66GO:0005576extracellular region
0.34GO:0005622intracellular
0.30GO:0016020membrane
0.37EC:1.13.99.1 GO:0050113
0.37KEGG:R01184 GO:0050113
sp|Q7Z4H7|HAUS6_HUMAN
HAUS augmin-like complex subunit 6
Search
HAUS6
0.96HAUS augmin like complex subunit 6
0.82GO:0051225spindle assembly
0.67GO:0007098centrosome cycle
0.41GO:0097711ciliary basal body-plasma membrane docking
0.40GO:0000086G2/M transition of mitotic cell cycle
0.39GO:0010389regulation of G2/M transition of mitotic cell cycle
0.36GO:0051301cell division
0.36GO:0005515protein binding
0.84GO:0070652HAUS complex
0.66GO:0016607nuclear speck
0.64GO:0005813centrosome
0.58GO:0005829cytosol
0.38GO:0005819spindle
0.37GO:0005874microtubule
sp|Q7Z4H8|KDEL2_HUMAN
KDEL motif-containing protein 2
Search
KDELC2
0.97KDEL motif-containing protein 2
0.64GO:0006664glycolipid metabolic process
0.40GO:0006886intracellular protein transport
0.34GO:0055114oxidation-reduction process
0.67GO:0046527glucosyltransferase activity
0.42GO:0017137Rab GTPase binding
0.34GO:0016491oxidoreductase activity
0.80GO:0005788endoplasmic reticulum lumen
0.30GO:0016021integral component of membrane
0.67EC:2.4.1 GO:0046527
sp|Q7Z4H9|F220A_HUMAN
Protein FAM220A
Search
C7ORF70
0.97STAT3-interacting protein as a repressor
sp|Q7Z4I7|LIMS2_HUMAN
LIM and senescent cell antigen-like-containing domain protein 2
Search
LIMS2
0.78LIM and senescent cell antigen-like-containing domain protein 2
0.62GO:0045216cell-cell junction organization
0.55GO:2000346negative regulation of hepatocyte proliferation
0.53GO:2001046positive regulation of integrin-mediated signaling pathway
0.52GO:2000178negative regulation of neural precursor cell proliferation
0.48GO:0043066negative regulation of apoptotic process
0.48GO:0098609cell-cell adhesion
0.41GO:0051894positive regulation of focal adhesion assembly
0.41GO:1900026positive regulation of substrate adhesion-dependent cell spreading
0.41GO:1901224positive regulation of NIK/NF-kappaB signaling
0.41GO:0033209tumor necrosis factor-mediated signaling pathway
0.53GO:0046872metal ion binding
0.39GO:0019901protein kinase binding
0.34GO:0019904protein domain specific binding
0.62GO:0005925focal adhesion
0.45GO:0005886plasma membrane
0.39GO:0048471perinuclear region of cytoplasm
0.39GO:0005911cell-cell junction
0.33GO:0005829cytosol
0.33GO:0005634nucleus
0.32GO:0043234protein complex
sp|Q7Z4J2|GL6D1_HUMAN
Glycosyltransferase 6 domain-containing protein 1
Search
GLT6D1
0.97Glycosyltransferase 6 domain-containing protein 1
0.60GO:0005975carbohydrate metabolic process
0.52GO:0030259lipid glycosylation
0.50GO:0009247glycolipid biosynthetic process
0.47GO:0033580protein galactosylation at cell surface
0.37GO:0006687glycosphingolipid metabolic process
0.37GO:0030148sphingolipid biosynthetic process
0.69GO:0016758transferase activity, transferring hexosyl groups
0.44GO:0008194UDP-glycosyltransferase activity
0.36GO:0046872metal ion binding
0.50GO:0005794Golgi apparatus
0.49GO:0031982vesicle
0.41GO:0098588bounding membrane of organelle
0.41GO:0031984organelle subcompartment
0.30GO:0031224intrinsic component of membrane
0.69EC:2.4.1 GO:0016758
sp|Q7Z4K8|TRI46_HUMAN
Tripartite motif-containing protein 46
Search
TRIM46
0.97Tripartite motif-containing protein 46
0.58GO:0048490anterograde synaptic vesicle transport
0.58GO:0099612protein localization to axon
0.56GO:0001764neuron migration
0.55GO:0001578microtubule bundle formation
0.54GO:0007409axonogenesis
0.62GO:0008270zinc ion binding
0.35GO:0008017microtubule binding
0.60GO:1990769proximal neuron projection
0.59GO:0043194axon initial segment
0.57GO:1904115axon cytoplasm
0.37GO:0005856cytoskeleton
0.30GO:0031224intrinsic component of membrane
sp|Q7Z4L0|COX8C_HUMAN
Cytochrome c oxidase subunit 8C, mitochondrial
Search
COX8C
0.97Cytochrome c oxidase subunit 8C, mitochondrial
0.63GO:1902600hydrogen ion transmembrane transport
0.61GO:0022900electron transport chain
0.44GO:0006119oxidative phosphorylation
0.44GO:0009060aerobic respiration
0.65GO:0015002heme-copper terminal oxidase activity
0.65GO:0016676oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63GO:0015078hydrogen ion transmembrane transporter activity
0.62GO:0009055electron transfer activity
0.58GO:0005739mitochondrion
0.48GO:0045277respiratory chain complex IV
0.43GO:0019866organelle inner membrane
0.30GO:0031224intrinsic component of membrane
0.65EC:1.9.3 GO:0016676
sp|Q7Z4L5|TT21B_HUMAN
Tetratricopeptide repeat protein 21B
Search
TTC21B
0.95Tetratricopeptide repeat protein 21B
0.76GO:0035721intraciliary retrograde transport
0.76GO:0061512protein localization to cilium
0.72GO:0021798forebrain dorsal/ventral pattern formation
0.69GO:0021591ventricular system development
0.68GO:0008589regulation of smoothened signaling pathway
0.66GO:0007224smoothened signaling pathway
0.59GO:0006357regulation of transcription by RNA polymerase II
0.51GO:0007369gastrulation
0.38GO:0035735intraciliary transport involved in cilium assembly
0.36GO:0006486protein glycosylation
0.54GO:0042802identical protein binding
0.35GO:0030246carbohydrate binding
0.35GO:0016757transferase activity, transferring glycosyl groups
0.76GO:0030991intraciliary transport particle A
0.66GO:0005929cilium
0.61GO:0000790nuclear chromatin
0.38GO:0005856cytoskeleton
0.37GO:0120038plasma membrane bounded cell projection part
0.35GO:0005794Golgi apparatus
0.30GO:0031224intrinsic component of membrane
0.35EC:2.4 GO:0016757
sp|Q7Z4L9|PPR42_HUMAN
Protein phosphatase 1 regulatory subunit 42
Search
PPP1R42
0.97LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 42
0.77GO:0010921regulation of phosphatase activity
0.33GO:0006508proteolysis
0.33GO:0007186G-protein coupled receptor signaling pathway
0.82GO:0070840dynein complex binding
0.72GO:0015631tubulin binding
0.72GO:0003779actin binding
0.34GO:0004222metalloendopeptidase activity
0.34GO:0046983protein dimerization activity
0.33GO:0004930G-protein coupled receptor activity
0.86GO:0002177manchette
0.76GO:0005813centrosome
0.37GO:0005737cytoplasm
0.35GO:0008180COP9 signalosome
0.30GO:0031224intrinsic component of membrane
0.34EC:3.4.24 GO:0004222
sp|Q7Z4M0|RE114_HUMAN
Meiotic recombination protein REC114
Search
REC114
0.97Meiotic recombination protein REC114
0.78GO:0051321meiotic cell cycle
0.65GO:0006310DNA recombination
0.51GO:0005515protein binding
sp|Q7Z4N2|TRPM1_HUMAN
Transient receptor potential cation channel subfamily M member 1
Search
TRPM1
0.96Long transient receptor potential channel 1
0.83GO:0007216G-protein coupled glutamate receptor signaling pathway
0.79GO:0051262protein tetramerization
0.76GO:0071482cellular response to light stimulus
0.60GO:0034220ion transmembrane transport
0.59GO:0006812cation transport
0.48GO:0007600sensory perception
0.48GO:0016048detection of temperature stimulus
0.47GO:0046548retinal rod cell development
0.44GO:0007204positive regulation of cytosolic calcium ion concentration
0.41GO:0051649establishment of localization in cell
0.72GO:0005261cation channel activity
0.43GO:0015085calcium ion transmembrane transporter activity
0.43GO:0022839ion gated channel activity
0.43GO:0008381mechanosensitive ion channel activity
0.47GO:0035841new growing cell tip
0.34GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q7Z4N8|P4HA3_HUMAN
Prolyl 4-hydroxylase subunit alpha-3
Search
P4HA3
0.79Prolyl 4-hydroxylase, alpha polypeptide III
0.81GO:0019511peptidyl-proline hydroxylation
0.53GO:0055114oxidation-reduction process
0.34GO:0007186G-protein coupled receptor signaling pathway
0.32GO:0005975carbohydrate metabolic process
0.82GO:0004656procollagen-proline 4-dioxygenase activity
0.79GO:0031418L-ascorbic acid binding
0.72GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62GO:0005506iron ion binding
0.34GO:0005515protein binding
0.34GO:0004930G-protein coupled receptor activity
0.33GO:0016868intramolecular transferase activity, phosphotransferases
0.68GO:0005783endoplasmic reticulum
0.38GO:0043233organelle lumen
0.36GO:0044446intracellular organelle part
0.34GO:1990204oxidoreductase complex
0.30GO:0031224intrinsic component of membrane
0.82EC:1.14.11.2 GO:0004656
0.82KEGG:R03219 GO:0004656
sp|Q7Z4P5|GDF7_HUMAN
Growth/differentiation factor 7
Search
0.90Growth differentiation factor 7
0.76GO:0010469regulation of receptor activity
0.64GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylation
0.63GO:0060389pathway-restricted SMAD protein phosphorylation
0.63GO:0032924activin receptor signaling pathway
0.61GO:0030509BMP signaling pathway
0.60GO:2001051positive regulation of tendon cell differentiation
0.60GO:0021509roof plate formation
0.58GO:0060395SMAD protein signal transduction
0.57GO:0045666positive regulation of neuron differentiation
0.57GO:0021527spinal cord association neuron differentiation
0.78GO:0008083growth factor activity
0.54GO:0042803protein homodimerization activity
0.53GO:0005160transforming growth factor beta receptor binding
0.51GO:0005125cytokine activity
0.36GO:0036122BMP binding
0.32GO:0003677DNA binding
0.66GO:0005576extracellular region
0.34GO:0005720nuclear heterochromatin
0.33GO:0005750mitochondrial respiratory chain complex III
sp|Q7Z4Q2|HEAT3_HUMAN
HEAT repeat-containing protein 3
Search
HEATR3
0.97HEAT repeat-containing protein 3
0.78GO:0006606protein import into nucleus
0.74GO:0042273ribosomal large subunit biogenesis
0.69GO:0051082unfolded protein binding
0.40GO:0016779nucleotidyltransferase activity
0.40EC:2.7.7 GO:0016779
sp|Q7Z4R8|CF120_HUMAN
UPF0669 protein C6orf120
Search
0.62GO:0006915apoptotic process
0.50GO:0043312neutrophil degranulation
0.48GO:0090305nucleic acid phosphodiester bond hydrolysis
0.36GO:0006281DNA repair
0.48GO:0004518nuclease activity
0.42GO:0003677DNA binding
0.36GO:0140097catalytic activity, acting on DNA
0.60GO:0005576extracellular region
0.51GO:0035578azurophil granule lumen
0.30GO:0016020membrane
0.48EC:3.1 GO:0004518
sp|Q7Z4S6|KI21A_HUMAN
Kinesin-like protein KIF21A
Search
KIF21A
0.94Kinesin family member 21A
0.74GO:0007018microtubule-based movement
0.75GO:0003777microtubule motor activity
0.74GO:0008017microtubule binding
0.55GO:0030554adenyl nucleotide binding
0.54GO:0097367carbohydrate derivative binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.45GO:0016887ATPase activity
0.55GO:0005829cytosol
0.54GO:0005871kinesin complex
0.47GO:0005886plasma membrane
0.45EC:3.6.1.3 GO:0016887
sp|Q7Z4S9|SH2D6_HUMAN
SH2 domain-containing protein 6
Search
SH2D6
0.96SH2 domain-containing protein 6
0.75GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
0.73GO:0009967positive regulation of signal transduction
0.71GO:0006955immune response
0.60GO:0035556intracellular signal transduction
0.85GO:0005068transmembrane receptor protein tyrosine kinase adaptor activity
0.82GO:0005070SH3/SH2 adaptor activity
0.41GO:0003723RNA binding
0.47GO:0005737cytoplasm
sp|Q7Z4T8|GLTL5_HUMAN
Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5
Search
GALNT11
0.57Polypeptide N-acetylgalactosaminyltransferase
0.68GO:0006486protein glycosylation
0.53GO:0018210peptidyl-threonine modification
0.51GO:0007286spermatid development
0.38GO:0061314Notch signaling involved in heart development
0.38GO:0007220Notch receptor processing
0.37GO:0008593regulation of Notch signaling pathway
0.37GO:0007368determination of left/right symmetry
0.37GO:0060271cilium assembly
0.63GO:0030246carbohydrate binding
0.60GO:0016757transferase activity, transferring glycosyl groups
0.54GO:0005112Notch binding
0.42GO:0140096catalytic activity, acting on a protein
0.35GO:0046872metal ion binding
0.66GO:0000139Golgi membrane
0.39GO:0031902late endosome membrane
0.30GO:0016021integral component of membrane
0.60EC:2.4 GO:0016757
sp|Q7Z4T9|CFA91_HUMAN
Cilia- and flagella-associated protein 91
Search
MAATS1
0.84MYCBP associated and testis expressed 1
0.65GO:0003341cilium movement
0.53GO:0006426glycyl-tRNA aminoacylation
0.45GO:0043401steroid hormone mediated signaling pathway
0.41GO:0006351transcription, DNA-templated
0.41GO:2000112regulation of cellular macromolecule biosynthetic process
0.41GO:1903506regulation of nucleic acid-templated transcription
0.41GO:0010468regulation of gene expression
0.53GO:0004820glycine-tRNA ligase activity
0.45GO:0003707steroid hormone receptor activity
0.45GO:0005515protein binding
0.44GO:0043565sequence-specific DNA binding
0.43GO:0008270zinc ion binding
0.43GO:0003700DNA binding transcription factor activity
0.42GO:0032559adenyl ribonucleotide binding
0.41GO:0008144drug binding
0.41GO:0035639purine ribonucleoside triphosphate binding
0.74GO:0001536radial spoke stalk
0.62GO:0031514motile cilium
0.50GO:0005739mitochondrion
0.43GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
0.53EC:6.1.1.14 GO:0004820
sp|Q7Z4U5|CF201_HUMAN
Uncharacterized protein C6orf201
Search
sp|Q7Z4V0|ZN438_HUMAN
Zinc finger protein 438
Search
ZNF438
0.97Zinc finger protein 438
0.44GO:0045892negative regulation of transcription, DNA-templated
0.35GO:0006351transcription, DNA-templated
0.33GO:0043043peptide biosynthetic process
0.33GO:0044267cellular protein metabolic process
0.51GO:0003676nucleic acid binding
0.40GO:0003700DNA binding transcription factor activity
0.35GO:0046872metal ion binding
0.34GO:0003735structural constituent of ribosome
0.48GO:0005654nucleoplasm
0.47GO:0005829cytosol
0.33GO:0005840ribosome
sp|Q7Z4V5|HDGR2_HUMAN
Hepatoma-derived growth factor-related protein 2
Search
HDGFL2
0.95Hepatoma-derived growth factor-related protein 2
0.79GO:0030307positive regulation of cell growth
0.59GO:0003682chromatin binding
0.52GO:0005515protein binding
0.38GO:0003677DNA binding
0.56GO:0005634nucleus
sp|Q7Z4W1|DCXR_HUMAN
L-xylulose reductase
Search
DCXR
0.70Dicarbonyl and L-xylulose reductase
0.54GO:0051262protein tetramerization
0.53GO:0005997xylulose metabolic process
0.52GO:0055114oxidation-reduction process
0.51GO:0051260protein homooligomerization
0.48GO:0006006glucose metabolic process
0.44GO:0006739NADP metabolic process
0.41GO:0042732D-xylose metabolic process
0.37GO:0019640glucuronate catabolic process to xylulose 5-phosphate
0.35GO:0006734NADH metabolic process
0.33GO:0007389pattern specification process
0.59GO:0050038L-xylulose reductase (NADP+) activity
0.49GO:0042802identical protein binding
0.47GO:0016655oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.43GO:0004090carbonyl reductase (NADPH) activity
0.41GO:0043621protein self-association
0.37GO:0047880erythrulose reductase activity
0.36GO:0033829O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.32GO:0046872metal ion binding
0.54GO:0005881cytoplasmic microtubule
0.49GO:0005902microvillus
0.49GO:0005903brush border
0.37GO:0043227membrane-bounded organelle
0.37GO:0043230extracellular organelle
0.36GO:0005615extracellular space
0.35GO:0097223sperm part
0.35GO:0016324apical plasma membrane
0.34GO:0031974membrane-enclosed lumen
0.34GO:0012505endomembrane system
0.59EC:1.1.1.10 GO:0050038
0.59KEGG:R01904 GO:0050038
sp|Q7Z4W2|LYZL2_HUMAN
Lysozyme-like protein 2
Search
0.49Lysozyme C, non-stomach isozyme
0.59GO:0042742defense response to bacterium
0.54GO:0019835cytolysis
0.47GO:0016998cell wall macromolecule catabolic process
0.40GO:0007342fusion of sperm to egg plasma membrane involved in single fertilization
0.38GO:0031640killing of cells of other organism
0.36GO:0007586digestion
0.33GO:0002159desmosome assembly
0.33GO:0050911detection of chemical stimulus involved in sensory perception of smell
0.32GO:0007186G-protein coupled receptor signaling pathway
0.32GO:0045824negative regulation of innate immune response
0.77GO:0003796lysozyme activity
0.37GO:0042802identical protein binding
0.33GO:0045294alpha-catenin binding
0.33GO:0004984olfactory receptor activity
0.33GO:0004930G-protein coupled receptor activity
0.32GO:0045296cadherin binding
0.32GO:0003723RNA binding
0.32GO:0005198structural molecule activity
0.47GO:0005615extracellular space
0.40GO:0097223sperm part
0.39GO:00977299+2 motile cilium
0.38GO:0044441ciliary part
0.35GO:0005886plasma membrane
0.34GO:0030667secretory granule membrane
0.33GO:0044437vacuolar part
0.33GO:0009986cell surface
0.32GO:0005913cell-cell adherens junction
0.32GO:0019898extrinsic component of membrane
0.77EC:3.2.1.17 GO:0003796
sp|Q7Z4W3|KR193_HUMAN
Keratin-associated protein 19-3
Search
0.97High tyrosine-glycine keratin-associated protein 19.1
0.58GO:0031424keratinization
0.42GO:0016560protein import into peroxisome matrix, docking
0.37GO:0070830bicellular tight junction assembly
0.36GO:0007010cytoskeleton organization
0.35GO:0071709membrane assembly
0.35GO:0006413translational initiation
0.39GO:0005515protein binding
0.38GO:0005198structural molecule activity
0.37GO:0030246carbohydrate binding
0.35GO:0003743translation initiation factor activity
0.34GO:0004386helicase activity
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.65GO:0005882intermediate filament
0.49GO:0005829cytosol
0.40GO:0042579microbody
0.37GO:0005578proteinaceous extracellular matrix
0.37GO:0016327apicolateral plasma membrane
0.36GO:0016324apical plasma membrane
0.36GO:0030139endocytic vesicle
0.36GO:0005923bicellular tight junction
0.34GO:0019867outer membrane
0.30GO:0016021integral component of membrane
sp|Q7Z4Y8|AT5L2_HUMAN
ATP synthase subunit g 2, mitochondrial
Search
ATP5L
0.87ATP synthase subunit gserine-threonine
0.70GO:0015985energy coupled proton transport, down electrochemical gradient
0.70GO:0006754ATP biosynthetic process
0.46GO:0099132ATP hydrolysis coupled cation transmembrane transport
0.36GO:0051568histone H3-K4 methylation
0.35GO:0042407cristae formation
0.35GO:0006839mitochondrial transport
0.34GO:0046907intracellular transport
0.34GO:0006511ubiquitin-dependent protein catabolic process
0.34GO:0016567protein ubiquitination
0.33GO:0006355regulation of transcription, DNA-templated
0.63GO:0015078hydrogen ion transmembrane transporter activity
0.47GO:0044769ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.46GO:0019829cation-transporting ATPase activity
0.36GO:0042800histone methyltransferase activity (H3-K4 specific)
0.36GO:0047624adenosine-tetraphosphatase activity
0.36GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.35GO:0034450ubiquitin-ubiquitin ligase activity
0.34GO:0008270zinc ion binding
0.33GO:0003677DNA binding
0.78GO:0000276mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.37GO:0070062extracellular exosome
0.36GO:0071339MLL1 complex
0.34GO:0000151ubiquitin ligase complex
0.30GO:0016021integral component of membrane
0.36EC:3.6.1.14 GO:0047624
sp|Q7Z553|MDGA2_HUMAN
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
Search
MDGA2
0.97MAM domain-containing glycosylphosphatidylinositol anchor protein 2
0.42GO:0021611facial nerve formation
0.41GO:0021731trigeminal motor nucleus development
0.41GO:1905483regulation of motor neuron migration
0.38GO:0021522spinal cord motor neuron differentiation
0.37GO:0007389pattern specification process
0.36GO:0006501C-terminal protein lipidation
0.39GO:0031225anchored component of membrane
0.35GO:0005886plasma membrane
0.34GO:0005576extracellular region
0.30GO:0016021integral component of membrane
sp|Q7Z569|BRAP_HUMAN
BRCA1-associated protein
Search
BRAP
0.79BRCA1 associated protein variant (Fragment)
0.54GO:0007265Ras protein signal transduction
0.53GO:0000165MAPK cascade
0.50GO:0009968negative regulation of signal transduction
0.50GO:0016567protein ubiquitination
0.35GO:0002091negative regulation of receptor internalization
0.35GO:0033962cytoplasmic mRNA processing body assembly
0.35GO:0034063stress granule assembly
0.63GO:0008270zinc ion binding
0.56GO:0008139nuclear localization sequence binding
0.52GO:0061630ubiquitin protein ligase activity
0.50GO:0042802identical protein binding
0.49GO:0003676nucleic acid binding
0.35GO:0005154epidermal growth factor receptor binding
0.34GO:0008022protein C-terminus binding
0.53GO:0031965nuclear membrane
0.51GO:0000151ubiquitin ligase complex
0.48GO:0005829cytosol
0.34GO:0005844polysome
0.34GO:0010494cytoplasmic stress granule
0.34GO:0005802trans-Golgi network
0.34GO:0048471perinuclear region of cytoplasm
0.30GO:0016021integral component of membrane
sp|Q7Z570|Z804A_HUMAN
Zinc finger protein 804A
Search
ZNF804A
0.50Zinc finger protein (Fragment)
0.66GO:0010976positive regulation of neuron projection development
0.59GO:0010628positive regulation of gene expression
0.45GO:1902952positive regulation of dendritic spine maintenance
0.52GO:0046872metal ion binding
0.49GO:0003676nucleic acid binding
0.75GO:1901588dendritic microtubule
0.69GO:0043198dendritic shaft
0.68GO:0043197dendritic spine
0.67GO:0030426growth cone
0.65GO:0043025neuronal cell body
0.51GO:0005634nucleus
0.47GO:0005886plasma membrane
0.43GO:0005737cytoplasm
0.42GO:0030424axon
0.42GO:0098793presynapse
sp|Q7Z572|SPT21_HUMAN
Spermatogenesis-associated protein 21
Search
SPATA21
0.97Spermatogenesis-associated protein 21
0.70GO:0005509calcium ion binding
sp|Q7Z589|EMSY_HUMAN
BRCA2-interacting transcriptional repressor EMSY
Search
EMSY
0.97EMSY, BRCA2 interacting transcriptional repressor
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.57GO:2001141regulation of RNA biosynthetic process
0.56GO:0010468regulation of gene expression
0.61GO:0042803protein homodimerization activity
0.56GO:0005654nucleoplasm
sp|Q7Z591|AKNA_HUMAN
AT-hook-containing transcription factor
Search
AKNA
0.97AT-hook-containing transcription factor
0.76GO:0006366transcription by RNA polymerase II
0.75GO:0045944positive regulation of transcription by RNA polymerase II
0.32GO:0006508proteolysis
0.82GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.80GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
0.32GO:0008234cysteine-type peptidase activity
0.83GO:0001650fibrillar center
0.78GO:0005813centrosome
0.70GO:0005654nucleoplasm
0.69GO:0005829cytosol
0.30GO:0016020membrane
0.32EC:3.4 GO:0008234
sp|Q7Z5A4|PRS42_HUMAN
Serine protease 42
Search
PRSS42
0.59Testis serine protease 2
0.61GO:0006508proteolysis
0.44GO:0007283spermatogenesis
0.44GO:0007281germ cell development
0.40GO:0035220wing disc development
0.40GO:0051017actin filament bundle assembly
0.37GO:0050878regulation of body fluid levels
0.36GO:0006959humoral immune response
0.36GO:0050817coagulation
0.36GO:0072376protein activation cascade
0.36GO:0042060wound healing
0.69GO:0004252serine-type endopeptidase activity
0.39GO:0005509calcium ion binding
0.33GO:0030246carbohydrate binding
0.33GO:0004222metalloendopeptidase activity
0.32GO:0003755peptidyl-prolyl cis-trans isomerase activity
0.32GO:0005515protein binding
0.45GO:0046658anchored component of plasma membrane
0.40GO:0005576extracellular region
0.37GO:0005737cytoplasm
0.34GO:0031983vesicle lumen
0.33GO:0097708intracellular vesicle
0.32GO:0012505endomembrane system
0.32GO:0070013intracellular organelle lumen
0.32GO:0044446intracellular organelle part
0.32GO:0043231intracellular membrane-bounded organelle
0.30GO:0016021integral component of membrane
0.69EC:3.4.21 GO:0004252
sp|Q7Z5A7|F19A5_HUMAN
Protein FAM19A5
Search
0.38GO:0005576extracellular region
0.30GO:0044425membrane part
sp|Q7Z5A8|F19A3_HUMAN
Protein FAM19A3
Search
0.70GO:1903979negative regulation of microglial cell activation
0.69GO:1903980positive regulation of microglial cell activation
0.36GO:0004386helicase activity
0.35GO:0005515protein binding
0.59GO:0005615extracellular space
0.55GO:0005783endoplasmic reticulum
0.30GO:0016021integral component of membrane
sp|Q7Z5A9|F19A1_HUMAN
Protein FAM19A1
Search
0.58GO:1903979negative regulation of microglial cell activation
0.57GO:1903980positive regulation of microglial cell activation
0.42GO:0051930regulation of sensory perception of pain
0.39GO:0042391regulation of membrane potential
0.36GO:0005515protein binding
0.62GO:0005783endoplasmic reticulum
0.50GO:0005615extracellular space
0.30GO:0044425membrane part
sp|Q7Z5B4|RIC3_HUMAN
Protein RIC-3
Search
RIC3
0.97Chaperone protein RIC-3
0.52GO:0043623cellular protein complex assembly
0.52GO:0034394protein localization to cell surface
0.52GO:0007271synaptic transmission, cholinergic
0.51GO:0006457protein folding
0.40GO:0007204positive regulation of cytosolic calcium ion concentration
0.61GO:0044183protein binding involved in protein folding
0.52GO:0033130acetylcholine receptor binding
0.32GO:0046872metal ion binding
0.52GO:0005783endoplasmic reticulum
0.49GO:0043025neuronal cell body
0.48GO:0043005neuron projection
0.37GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.37GO:0031984organelle subcompartment
0.35GO:0044431Golgi apparatus part
0.35GO:0098588bounding membrane of organelle
0.30GO:0031224intrinsic component of membrane
sp|Q7Z5D8|NANGN_HUMAN
NANOG neighbor homeobox
Search
NANOGNB
0.97NANOG neighbor homeobox
0.39GO:0050794regulation of cellular process
0.39GO:0023051regulation of signaling
0.39GO:0016477cell migration
0.38GO:0048583regulation of response to stimulus
0.38GO:0060255regulation of macromolecule metabolic process
0.38GO:0032879regulation of localization
0.38GO:0000398mRNA splicing, via spliceosome
0.38GO:0051171regulation of nitrogen compound metabolic process
0.38GO:0080090regulation of primary metabolic process
0.38GO:0050790regulation of catalytic activity
0.50GO:0003677DNA binding
0.38GO:0005515protein binding
0.37GO:0046872metal ion binding
0.36GO:0043168anion binding
0.36GO:1901265nucleoside phosphate binding
0.36GO:0000989transcription factor activity, transcription factor binding
0.36GO:0015081sodium ion transmembrane transporter activity
0.36GO:0016746transferase activity, transferring acyl groups
0.36GO:0097367carbohydrate derivative binding
0.36GO:0036094small molecule binding
0.56GO:0005634nucleus
0.39GO:0070013intracellular organelle lumen
0.39GO:0044446intracellular organelle part
0.37GO:0005856cytoskeleton
0.37GO:0005829cytosol
0.36GO:0048786presynaptic active zone
0.35GO:0120114Sm-like protein family complex
0.35GO:0005773vacuole
0.35GO:0012505endomembrane system
0.35GO:0005925focal adhesion
0.36EC:2.3 GO:0016746
0.36KEGG:R01881 GO:0004111
sp|Q7Z5G4|GOGA7_HUMAN
Golgin subfamily A member 7
Search
GOLGA7
0.93Golgi complex-associated protein of 16 kDa
0.86GO:0018231peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.85GO:0018345protein palmitoylation
0.84GO:0043001Golgi to plasma membrane protein transport
0.75GO:0050821protein stabilization
0.61GO:0006612protein targeting to membrane
0.40GO:0043312neutrophil degranulation
0.36GO:0006260DNA replication
0.64GO:0019706protein-cysteine S-palmitoyltransferase activity
0.36GO:0005515protein binding
0.85GO:0002178palmitoyltransferase complex
0.78GO:0005795Golgi stack
0.77GO:0031228intrinsic component of Golgi membrane
0.43GO:0070062extracellular exosome
0.41GO:1904724tertiary granule lumen
0.36GO:0005634nucleus
0.30GO:0016021integral component of membrane
0.64EC:2.3.1.225 GO:0019706
sp|Q7Z5H3|RHG22_HUMAN
Rho GTPase-activating protein 22
Search
ARHGAP22
0.91Rho GTPase-activating protein 22
0.67GO:0043547positive regulation of GTPase activity
0.61GO:0007165signal transduction
0.37GO:0001525angiogenesis
0.36GO:0030154cell differentiation
0.35GO:0051056regulation of small GTPase mediated signal transduction
0.34GO:0006351transcription, DNA-templated
0.34GO:2001141regulation of RNA biosynthetic process
0.34GO:2000112regulation of cellular macromolecule biosynthetic process
0.34GO:0010468regulation of gene expression
0.67GO:0005096GTPase activator activity
0.35GO:0016757transferase activity, transferring glycosyl groups
0.34GO:0005515protein binding
0.38GO:0005925focal adhesion
0.35GO:0005634nucleus
0.34GO:0005829cytosol
0.35EC:2.4 GO:0016757
sp|Q7Z5H4|VN1R5_HUMAN
Vomeronasal type-1 receptor 5
Search
0.43Vomeronasal type-1 receptor
0.82GO:0019236response to pheromone
0.71GO:0007186G-protein coupled receptor signaling pathway
0.46GO:0007606sensory perception of chemical stimulus
0.83GO:0016503pheromone receptor activity
0.38GO:0005550pheromone binding
0.56GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q7Z5H5|VN1R4_HUMAN
Vomeronasal type-1 receptor 4
Search
V1R
0.59Vomeronasal type-1 receptor
0.81GO:0019236response to pheromone
0.71GO:0007186G-protein coupled receptor signaling pathway
0.45GO:0007606sensory perception of chemical stimulus
0.83GO:0016503pheromone receptor activity
0.36GO:0005550pheromone binding
0.55GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q7Z5J1|DHI1L_HUMAN
Hydroxysteroid 11-beta-dehydrogenase 1-like protein
Search
HSD11B1L
0.6711-beta-hydroxysteroid dehydrogenase long form
0.52GO:0055114oxidation-reduction process
0.33GO:0006412translation
0.53GO:0016491oxidoreductase activity
0.34GO:0070403NAD+ binding
0.34GO:0003735structural constituent of ribosome
0.32GO:0016740transferase activity
0.50GO:0005654nucleoplasm
0.40GO:0005576extracellular region
0.34GO:0005840ribosome
0.30GO:0031224intrinsic component of membrane
0.53EC:1 GO:0016491
sp|Q7Z5J4|RAI1_HUMAN
Retinoic acid-induced protein 1
Search
RAI1
0.96Retinoic acid-induced protein 1
0.65GO:0040015negative regulation of multicellular organism growth
0.65GO:0032922circadian regulation of gene expression
0.59GO:0001501skeletal system development
0.57GO:0045893positive regulation of transcription, DNA-templated
0.55GO:0006357regulation of transcription by RNA polymerase II
0.33GO:0006366transcription by RNA polymerase II
0.63GO:0035326enhancer binding
0.52GO:0046872metal ion binding
0.45GO:0003700DNA binding transcription factor activity
0.36GO:0005515protein binding
0.34GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
0.33GO:0003713transcription coactivator activity
0.32GO:0003723RNA binding
0.55GO:0005654nucleoplasm
0.49GO:0005739mitochondrion
sp|Q7Z5J8|ANKAR_HUMAN
Ankyrin and armadillo repeat-containing protein
Search
ANKAR
0.97Ankyrin and armadillo repeat containing
0.42GO:0006298mismatch repair
0.39GO:0034333adherens junction assembly
0.35GO:0007165signal transduction
0.42GO:0030983mismatched DNA binding
0.37GO:0030554adenyl nucleotide binding
0.37GO:0097367carbohydrate derivative binding
0.37GO:0008144drug binding
0.37GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0004871signal transducer activity
0.59GO:0005634nucleus
0.47GO:0005737cytoplasm
0.30GO:0044425membrane part
sp|Q7Z5K2|WAPL_HUMAN
Wings apart-like protein homolog
Search
WAPL
0.94WAPL cohesin release factor a
0.87GO:0071922regulation of cohesin loading
0.85GO:0035562negative regulation of chromatin binding
0.85GO:0060623regulation of chromosome condensation
0.85GO:0045875negative regulation of sister chromatid cohesion
0.84GO:0071168protein localization to chromatin
0.80GO:0048146positive regulation of fibroblast proliferation
0.78GO:0008156negative regulation of DNA replication
0.73GO:0000278mitotic cell cycle
0.64GO:0045132meiotic chromosome segregation
0.63GO:0009636response to toxic substance
0.81GO:0008278cohesin complex
0.78GO:0000795synaptonemal complex
0.69GO:0000785chromatin
0.47GO:0005737cytoplasm
sp|Q7Z5L0|VMO1_HUMAN
Vitelline membrane outer layer protein 1 homolog
Search
VMO1
0.88Vitelline membrane outer layer protein 1
0.40GO:0006629lipid metabolic process
0.48GO:0005509calcium ion binding
0.43GO:0008081phosphoric diester hydrolase activity
0.55GO:0005615extracellular space
0.45GO:1903561extracellular vesicle
0.30GO:0031224intrinsic component of membrane
0.30GO:0005623cell
0.43EC:3.1.4 GO:0008081
sp|Q7Z5L2|R3HCL_HUMAN
Coiled-coil domain-containing protein R3HCC1L
Search
R3HCC1L
0.94Growth inhibition and differentiation-related protein 88
0.47GO:0003676nucleic acid binding
0.37GO:0005515protein binding
0.35GO:0005549odorant binding
0.63GO:0035145exon-exon junction complex
sp|Q7Z5L3|C1QL2_HUMAN
Complement C1q-like protein 2
Search
C1QL2
0.97Complement component 1, q subcomponent-like 2
0.52GO:0051259protein oligomerization
0.50GO:0050807regulation of synapse organization
0.57GO:0042802identical protein binding
0.70GO:0005581collagen trimer
0.63GO:0005576extracellular region
0.30GO:0031224intrinsic component of membrane
sp|Q7Z5L4|SPT19_HUMAN
Spermatogenesis-associated protein 19, mitochondrial
Search
SPATA19
0.97Spermatogenesis-associated protein 19, mitochondrial
0.80GO:0007283spermatogenesis
0.72GO:0030154cell differentiation
0.70GO:0007275multicellular organism development
0.78GO:0005741mitochondrial outer membrane
sp|Q7Z5L7|PODN_HUMAN
Podocan
Search
PODN
0.97Podocan
0.79GO:0030336negative regulation of cell migration
0.76GO:0008285negative regulation of cell proliferation
0.66GO:0046426negative regulation of JAK-STAT cascade
0.62GO:0006469negative regulation of protein kinase activity
0.62GO:0019221cytokine-mediated signaling pathway
0.32GO:0006468protein phosphorylation
0.79GO:0005518collagen binding
0.64GO:0004860protein kinase inhibitor activity
0.32GO:0004672protein kinase activity
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.73GO:0031012extracellular matrix
0.70GO:0005615extracellular space
0.48GO:0005737cytoplasm
0.30GO:0016020membrane
sp|Q7Z5L9|I2BP2_HUMAN
Interferon regulatory factor 2-binding protein 2
Search
IRF2BP2
0.96Interferon regulatory factor 2-binding protein 2
0.45GO:0000122negative regulation of transcription by RNA polymerase II
0.44GO:0006351transcription, DNA-templated
0.39GO:0045944positive regulation of transcription by RNA polymerase II
0.44GO:0046872metal ion binding
0.44GO:0003714transcription corepressor activity
0.66GO:0005654nucleoplasm
0.37GO:0005737cytoplasm
sp|Q7Z5M5|TMC3_HUMAN
Transmembrane channel-like protein 3
Search
TMC3
0.83Transmembrane channel-like protein 3
0.35GO:0006811ion transport
0.30GO:0016021integral component of membrane
sp|Q7Z5M8|AB12B_HUMAN
Protein ABHD12B
Search
ABHD12B
0.86Abhydrolase domain-containing protein 12
0.54GO:0052651monoacylglycerol catabolic process
0.53GO:0006660phosphatidylserine catabolic process
0.51GO:0010996response to auditory stimulus
0.51GO:0007628adult walking behavior
0.50GO:0002084protein depalmitoylation
0.40GO:0048899anterior lateral line development
0.40GO:0036269swimming behavior
0.39GO:0048919posterior lateral line neuromast development
0.39GO:0010842retina layer formation
0.38GO:0042552myelination
0.72GO:0047372acylglycerol lipase activity
0.50GO:0008474palmitoyl-(protein) hydrolase activity
0.50GO:0004622lysophospholipase activity
0.51GO:0032839dendrite cytoplasm
0.51GO:0032281AMPA glutamate receptor complex
0.32GO:0005739mitochondrion
0.72EC:3.1.1.23 GO:0047372
sp|Q7Z5N4|SDK1_HUMAN
Protein sidekick-1
Search
SDK1
0.97Sidekick cell adhesion molecule 1
0.58GO:0048148behavioral response to cocaine
0.57GO:0060998regulation of dendritic spine development
0.42GO:0010842retina layer formation
0.41GO:0007416synapse assembly
0.40GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.36GO:0045216cell-cell junction organization
0.33GO:0060219camera-type eye photoreceptor cell differentiation
0.32GO:1903506regulation of nucleic acid-templated transcription
0.32GO:2000112regulation of cellular macromolecule biosynthetic process
0.32GO:0010468regulation of gene expression
0.39GO:0042802identical protein binding
0.32GO:0043565sequence-specific DNA binding
0.32GO:0003700DNA binding transcription factor activity
0.39GO:0045202synapse
0.39GO:0030054cell junction
0.36GO:0070062extracellular exosome
0.35GO:0005886plasma membrane
0.32GO:0005634nucleus
0.30GO:0016021integral component of membrane
sp|Q7Z5P4|DHB13_HUMAN
17-beta-hydroxysteroid dehydrogenase 13
Search
HSD17B11
0.9017-beta-hydroxysteroid dehydrogenase 13
0.70GO:0046889positive regulation of lipid biosynthetic process
0.66GO:0006710androgen catabolic process
0.45GO:0055114oxidation-reduction process
0.41GO:0034389lipid particle organization
0.59GO:0016229steroid dehydrogenase activity
0.78GO:0005811lipid droplet
0.41GO:0005737cytoplasm
0.41GO:0005576extracellular region
0.30GO:0031224intrinsic component of membrane
0.59EC:1.1.1 GO:0016229
sp|Q7Z5P9|MUC19_HUMAN
Mucin-19
Search
0.65GO:0002223stimulatory C-type lectin receptor signaling pathway
0.62GO:0016266O-glycan processing
0.49GO:0060689cell differentiation involved in salivary gland development
0.47GO:0050728negative regulation of inflammatory response
0.47GO:0002244hematopoietic progenitor cell differentiation
0.40GO:0043030regulation of macrophage activation
0.38GO:0042742defense response to bacterium
0.34GO:0007605sensory perception of sound
0.34GO:0010466negative regulation of peptidase activity
0.33GO:0000128flocculation
0.35GO:0005515protein binding
0.34GO:0030414peptidase inhibitor activity
0.32GO:0004672protein kinase activity
0.32GO:0032550purine ribonucleoside binding
0.32GO:0019001guanyl nucleotide binding
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.66GO:0005576extracellular region
0.64GO:0005796Golgi lumen
0.56GO:0031982vesicle
0.44GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q7Z5Q1|CPEB2_HUMAN
Cytoplasmic polyadenylation element-binding protein 2
Search
CPEB2
0.90Cytoplasmic polyadenylation element binding protein 2 variant B
0.71GO:0006417regulation of translation
0.50GO:0034249negative regulation of cellular amide metabolic process
0.50GO:0071456cellular response to hypoxia
0.49GO:0032869cellular response to insulin stimulus
0.48GO:0032269negative regulation of cellular protein metabolic process
0.48GO:2000113negative regulation of cellular macromolecule biosynthetic process
0.47GO:0071243cellular response to arsenic-containing substance
0.46GO:0010629negative regulation of gene expression
0.43GO:0034599cellular response to oxidative stress
0.41GO:0034260negative regulation of GTPase activity
0.83GO:0003730mRNA 3'-UTR binding
0.82GO:0045182translation regulator activity
0.47GO:0043022ribosome binding
0.47GO:0017091AU-rich element binding
0.45GO:0008187poly-pyrimidine tract binding
0.43GO:0008135translation factor activity, RNA binding
0.42GO:0005095GTPase inhibitor activity
0.41GO:0043024ribosomal small subunit binding
0.40GO:0043023ribosomal large subunit binding
0.35GO:0005515protein binding
0.54GO:1990124messenger ribonucleoprotein complex
0.46GO:0043005neuron projection
0.46GO:0045202synapse
0.44GO:0005844polysome
0.44GO:0005634nucleus
0.38GO:0005737cytoplasm
0.36GO:0036477somatodendritic compartment
0.36GO:0120038plasma membrane bounded cell projection part
0.35GO:0012505endomembrane system
0.33EC:1.14 GO:0016705
sp|Q7Z5Q5|DPOLN_HUMAN
DNA polymerase nu
Search
POLN
0.97DNA polymerase nu
0.70GO:0006261DNA-dependent DNA replication
0.66GO:0071897DNA biosynthetic process
0.62GO:0006301postreplication repair
0.60GO:0036297interstrand cross-link repair
0.57GO:0000724double-strand break repair via homologous recombination
0.42GO:0022616DNA strand elongation
0.39GO:0090305nucleic acid phosphodiester bond hydrolysis
0.36GO:0051225spindle assembly
0.32GO:0043043peptide biosynthetic process
0.32GO:0044267cellular protein metabolic process
0.70GO:0003887DNA-directed DNA polymerase activity
0.60GO:0030332cyclin binding
0.54GO:0003677DNA binding
0.47GO:0004527exonuclease activity
0.32GO:0003735structural constituent of ribosome
0.53GO:0005654nucleoplasm
0.39GO:0005730nucleolus
0.37GO:0005737cytoplasm
0.36GO:0070652HAUS complex
0.32GO:0030529intracellular ribonucleoprotein complex
0.70EC:2.7.7.7 GO:0003887
sp|Q7Z5R6|AB1IP_HUMAN
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
Search
APBB1IP
0.97Amyloid beta A4 protein-binding family B member 1-interacting protein isoform A
0.62GO:0002291T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.59GO:0007165signal transduction
0.53GO:0045785positive regulation of cell adhesion
0.35GO:0005515protein binding
0.59GO:0042101T cell receptor complex
0.49GO:0005829cytosol
0.38GO:0030027lamellipodium
0.38GO:0005856cytoskeleton
0.38GO:0005925focal adhesion
0.30GO:0031224intrinsic component of membrane
sp|Q7Z5S9|TM144_HUMAN
Transmembrane protein 144
Search
TMEM144
0.97Transmembrane protein 144
0.72GO:0034219carbohydrate transmembrane transport
0.71GO:0015144carbohydrate transmembrane transporter activity
0.30GO:0044425membrane part
sp|Q7Z5U6|WDR53_HUMAN
WD repeat-containing protein 53
Search
WDR53
0.97WD repeat-containing protein 53
0.33GO:0051301cell division
0.33GO:0007049cell cycle
0.33GO:0007165signal transduction
0.48GO:0005737cytoplasm
0.34GO:0005874microtubule
0.30GO:0031224intrinsic component of membrane
sp|Q7Z5V6|PPR32_HUMAN
Protein phosphatase 1 regulatory subunit 32
Search
PPP1R32
0.63Succinate dehydrogenase assembly factor 2, mitochondrial
0.39GO:0018293protein-FAD linkage
0.39GO:0006121mitochondrial electron transport, succinate to ubiquinone
0.82GO:0019902phosphatase binding
0.37GO:0005759mitochondrial matrix
sp|Q7Z5W3|BN3D2_HUMAN
Pre-miRNA 5'-monophosphate methyltransferase
Search
BCDIN3D
0.97Pre-miRNA 5'-monophosphate methyltransferase
0.63GO:0032259methylation
0.63GO:2000632negative regulation of pre-miRNA processing
0.60GO:0010586miRNA metabolic process
0.48GO:0009451RNA modification
0.39GO:0044260cellular macromolecule metabolic process
0.63GO:0008168methyltransferase activity
0.46GO:0140098catalytic activity, acting on RNA
0.34GO:0003723RNA binding
0.34GO:0005515protein binding
0.48GO:0005829cytosol
0.45GO:0005634nucleus
0.30GO:0016020membrane
0.63EC:2.1.1 GO:0008168
sp|Q7Z5Y6|BMP8A_HUMAN
Bone morphogenetic protein 8A
Search
0.85Bone morphogenetic protein 5
0.74GO:0010469regulation of receptor activity
0.57GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylation
0.56GO:0060395SMAD protein signal transduction
0.55GO:0030509BMP signaling pathway
0.52GO:0043408regulation of MAPK cascade
0.52GO:0048468cell development
0.50GO:0042981regulation of apoptotic process
0.45GO:0002024diet induced thermogenesis
0.45GO:0001503ossification
0.45GO:2000505regulation of energy homeostasis
0.77GO:0008083growth factor activity
0.59GO:0070700BMP receptor binding
0.56GO:0005160transforming growth factor beta receptor binding
0.53GO:0005125cytokine activity
0.35GO:0008410CoA-transferase activity
0.34GO:0046982protein heterodimerization activity
0.34GO:0008017microtubule binding
0.33GO:0005509calcium ion binding
0.32GO:0003779actin binding
0.32GO:0030554adenyl nucleotide binding
0.65GO:0005576extracellular region
0.34GO:0031982vesicle
0.32GO:0005737cytoplasm
0.32GO:0005856cytoskeleton
0.32GO:0043231intracellular membrane-bounded organelle
0.30GO:0016020membrane
0.35EC:2.8.3 GO:0008410
sp|Q7Z5Y7|KCD20_HUMAN
BTB/POZ domain-containing protein KCTD20
Search
KCTD20
0.95Potassium channel tetramerisation domain containing 20
0.77GO:0042327positive regulation of phosphorylation
0.40GO:0042802identical protein binding
0.49GO:0005737cytoplasm
sp|Q7Z601|GP142_HUMAN
Probable G-protein coupled receptor 142
Search
GPR142
0.92G-protein coupled receptor 142 short form
0.71GO:0007186G-protein coupled receptor signaling pathway
0.72GO:0004930G-protein coupled receptor activity
0.54GO:0030054cell junction
0.51GO:0005829cytosol
0.44GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q7Z602|GP141_HUMAN
Probable G-protein coupled receptor 141
Search
GPR141
0.97G protein-coupled receptor 141-va
0.67GO:0007186G-protein coupled receptor signaling pathway
0.68GO:0004930G-protein coupled receptor activity
0.34GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q7Z614|SNX20_HUMAN
Sorting nexin-20
Search
SNX20
0.97Sorting nexin-20
0.39GO:0015031protein transport
0.76GO:0035091phosphatidylinositol binding
0.35GO:0005515protein binding
0.53GO:0005654nucleoplasm
0.43GO:0031901early endosome membrane
0.36GO:0005886plasma membrane
sp|Q7Z624|CMKMT_HUMAN
Calmodulin-lysine N-methyltransferase
Search
CAMKMT
0.95Calmodulin-lysine N-methyltransferase
0.61GO:0018022peptidyl-lysine methylation
0.53GO:0007005mitochondrion organization
0.37GO:0022400regulation of rhodopsin mediated signaling pathway
0.34GO:0006633fatty acid biosynthetic process
0.72GO:0018025calmodulin-lysine N-methyltransferase activity
0.55GO:0031072heat shock protein binding
0.33GO:0016747transferase activity, transferring acyl groups other than amino-acyl groups
0.33GO:0003677DNA binding
0.47GO:0005634nucleus
0.45GO:0043234protein complex
0.42GO:0005737cytoplasm
0.36GO:0012505endomembrane system
0.30GO:0016020membrane
0.72EC:2.1.1.60 GO:0018025
sp|Q7Z628|ARHG8_HUMAN
Neuroepithelial cell-transforming gene 1 protein
Search
NET1
0.97Neuroepithelial cell transforming gene 1
0.78GO:0035023regulation of Rho protein signal transduction
0.66GO:0065009regulation of molecular function
0.62GO:0035556intracellular signal transduction
0.56GO:0051451myoblast migration
0.55GO:1900026positive regulation of substrate adhesion-dependent cell spreading
0.54GO:0071479cellular response to ionizing radiation
0.54GO:0070301cellular response to hydrogen peroxide
0.51GO:0043065positive regulation of apoptotic process
0.48GO:2000055positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
0.47GO:0044332Wnt signaling pathway involved in dorsal/ventral axis specification
0.78GO:0005089Rho guanyl-nucleotide exchange factor activity
0.55GO:0017049GTP-Rho binding
0.33GO:0005509calcium ion binding
0.45GO:0005622intracellular
0.41GO:0043227membrane-bounded organelle
0.41GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q7Z692|CEA19_HUMAN
Carcinoembryonic antigen-related cell adhesion molecule 19
Search
CEACAM19
0.97Carcinoembryonic antigen-related cell adhesion molecule 19 transcript variant 3
0.37GO:0005515protein binding
0.30GO:0044425membrane part
sp|Q7Z695|ADCK2_HUMAN
Uncharacterized aarF domain-containing protein kinase 2
Search
ADCK2
0.97AarF domain-containing protein kinase 2
0.55GO:0016310phosphorylation
0.46GO:0006464cellular protein modification process
0.57GO:0016301kinase activity
0.47GO:0016773phosphotransferase activity, alcohol group as acceptor
0.45GO:0140096catalytic activity, acting on a protein
0.43GO:0030554adenyl nucleotide binding
0.42GO:0097367carbohydrate derivative binding
0.42GO:0008144drug binding
0.42GO:0035639purine ribonucleoside triphosphate binding
0.37GO:0005739mitochondrion
0.30GO:0031224intrinsic component of membrane
0.47EC:2.7.1 GO:0016773
sp|Q7Z698|SPRE2_HUMAN
Sprouty-related, EVH1 domain-containing protein 2
Search
SPRED2
0.97Sprouty-related, EVH1 domain-containing protein 2 isoform a
0.69GO:0007275multicellular organism development
0.69GO:0009966regulation of signal transduction
0.52GO:0090311regulation of protein deacetylation
0.51GO:2001022positive regulation of response to DNA damage stimulus
0.51GO:0010801negative regulation of peptidyl-threonine phosphorylation
0.50GO:0071901negative regulation of protein serine/threonine kinase activity
0.48GO:0023056positive regulation of signaling
0.48GO:0010647positive regulation of cell communication
0.47GO:0023057negative regulation of signaling
0.47GO:0010648negative regulation of cell communication
0.54GO:0005173stem cell factor receptor binding
0.51GO:0030291protein serine/threonine kinase inhibitor activity
0.49GO:0019901protein kinase binding
0.47GO:0031410cytoplasmic vesicle
0.41GO:0005886plasma membrane
0.40GO:0012506vesicle membrane
0.39GO:0098805whole membrane
0.39GO:0098588bounding membrane of organelle
0.38GO:0012505endomembrane system
0.36GO:0044446intracellular organelle part
0.34GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q7Z699|SPRE1_HUMAN
Sprouty-related, EVH1 domain-containing protein 1
Search
SPRED1
0.94Sprouty-related, EVH1 domain-containing protein 1
0.69GO:0009966regulation of signal transduction
0.68GO:0007275multicellular organism development
0.60GO:0090051negative regulation of cell migration involved in sprouting angiogenesis
0.60GO:0090311regulation of protein deacetylation
0.59GO:0010801negative regulation of peptidyl-threonine phosphorylation
0.59GO:2001022positive regulation of response to DNA damage stimulus
0.57GO:0006469negative regulation of protein kinase activity
0.57GO:0010923negative regulation of phosphatase activity
0.55GO:0071900regulation of protein serine/threonine kinase activity
0.54GO:0023056positive regulation of signaling
0.62GO:0005173stem cell factor receptor binding
0.58GO:0030291protein serine/threonine kinase inhibitor activity
0.57GO:0019902phosphatase binding
0.56GO:0019901protein kinase binding
0.53GO:0031410cytoplasmic vesicle
0.50GO:0005829cytosol
0.46GO:0005634nucleus
0.38GO:0005901caveola
0.30GO:0016021integral component of membrane
sp|Q7Z6A9|BTLA_HUMAN
B- and T-lymphocyte attenuator
Search
BTLA
0.94B and T lymphocyte associated
0.30GO:0044425membrane part
sp|Q7Z6B0|CCD91_HUMAN
Coiled-coil domain-containing protein 91
Search
CCDC91
0.97Coiled-coil domain-containing protein 91
0.75GO:0048193Golgi vesicle transport
0.60GO:0007041lysosomal transport
0.57GO:0016482cytosolic transport
0.38GO:0015031protein transport
0.54GO:0042802identical protein binding
0.57GO:0005802trans-Golgi network
0.52GO:0005654nucleoplasm
0.51GO:0005829cytosol
0.30GO:0016020membrane
sp|Q7Z6B7|SRGP1_HUMAN
SLIT-ROBO Rho GTPase-activating protein 1
Search
SRGAP1
0.88SLIT-ROBO Rho GTPase-activating protein 1
0.74GO:0043547positive regulation of GTPase activity
0.60GO:0007165signal transduction
0.45GO:0030336negative regulation of cell migration
0.35GO:0016477cell migration
0.35GO:0051056regulation of small GTPase mediated signal transduction
0.75GO:0005096GTPase activator activity
0.46GO:0048365Rac GTPase binding
0.36GO:0005737cytoplasm
sp|Q7Z6E9|RBBP6_HUMAN
E3 ubiquitin-protein ligase RBBP6
Search
RBBP6
0.96RB binding protein 6, ubiquitin ligase
0.73GO:0016567protein ubiquitination
0.70GO:0006397mRNA processing
0.70GO:0035264multicellular organism growth
0.70GO:0061053somite development
0.66GO:0048568embryonic organ development
0.65GO:0006275regulation of DNA replication
0.63GO:0001701in utero embryonic development
0.62GO:0006511ubiquitin-dependent protein catabolic process
0.56GO:0006974cellular response to DNA damage stimulus
0.76GO:0061630ubiquitin protein ligase activity
0.66GO:0019901protein kinase binding
0.63GO:0008270zinc ion binding
0.51GO:0003676nucleic acid binding
0.67GO:0016607nuclear speck
0.66GO:0005813centrosome
0.52GO:0043234protein complex
sp|Q7Z6G3|NECA2_HUMAN
N-terminal EF-hand calcium-binding protein 2
Search
NECAB2
0.96N-terminal EF-hand calcium-binding protein 2
0.58GO:1904021negative regulation of G-protein coupled receptor internalization
0.57GO:0060168positive regulation of adenosine receptor signaling pathway
0.57GO:1900451positive regulation of glutamate receptor signaling pathway
0.53GO:0070374positive regulation of ERK1 and ERK2 cascade
0.50GO:1905477positive regulation of protein localization to membrane
0.40GO:0042984regulation of amyloid precursor protein biosynthetic process
0.35GO:0019722calcium-mediated signaling
0.35GO:0030308negative regulation of cell growth
0.35GO:0043065positive regulation of apoptotic process
0.34GO:0019538protein metabolic process
0.69GO:0005509calcium ion binding
0.59GO:0031687A2A adenosine receptor binding
0.58GO:0031802type 5 metabotropic glutamate receptor binding
0.38GO:0042802identical protein binding
0.41GO:0005886plasma membrane
0.40GO:0005654nucleoplasm
0.40GO:0005829cytosol
0.40GO:0000137Golgi cis cisterna
0.39GO:0030425dendrite
0.39GO:0030424axon
0.37GO:0005783endoplasmic reticulum
0.37GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.30GO:0044425membrane part
sp|Q7Z6G8|ANS1B_HUMAN
Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Search
ANKS1B
0.85Ankyrin repeat and sterile alpha motif domain-containing protein 1B
0.86GO:1900383regulation of synaptic plasticity by receptor localization to synapse
0.58GO:0046875ephrin receptor binding
0.48GO:0005829cytosol
0.43GO:0043231intracellular membrane-bounded organelle
0.43GO:0005886plasma membrane
0.42GO:0043197dendritic spine
0.42GO:0014069postsynaptic density
0.40GO:0030054cell junction
0.37GO:0031974membrane-enclosed lumen
0.35GO:0044446intracellular organelle part
0.30GO:0044425membrane part
sp|Q7Z6I5|SPT12_HUMAN
Spermatogenesis-associated protein 12
Search
SPATA12
0.97Spermatogenesis-associated protein 12
sp|Q7Z6I6|RHG30_HUMAN
Rho GTPase-activating protein 30
Search
ARHGAP30
0.97Rho GTPase-activating protein 30
0.60GO:0007165signal transduction
0.51GO:0043547positive regulation of GTPase activity
0.36GO:0051056regulation of small GTPase mediated signal transduction
0.36GO:0015031protein transport
0.51GO:0005096GTPase activator activity
0.41GO:0017124SH3 domain binding
0.38GO:0035091phosphatidylinositol binding
0.36GO:0046983protein dimerization activity
0.33GO:0019901protein kinase binding
0.45GO:0043231intracellular membrane-bounded organelle
0.42GO:0030027lamellipodium
0.38GO:0031410cytoplasmic vesicle
0.35GO:0005829cytosol
0.35GO:0005938cell cortex
0.35GO:0015629actin cytoskeleton
0.32GO:0012505endomembrane system
0.32GO:0031974membrane-enclosed lumen
0.32GO:0043234protein complex
0.32GO:0044446intracellular organelle part
sp|Q7Z6I8|CE024_HUMAN
UPF0461 protein C5orf24
Search
0.36GO:0006269DNA replication, synthesis of RNA primer
0.57GO:0004386helicase activity
0.50GO:0030554adenyl nucleotide binding
0.49GO:0097367carbohydrate derivative binding
0.49GO:0008144drug binding
0.49GO:0035639purine ribonucleoside triphosphate binding
0.47GO:0003676nucleic acid binding
0.43GO:0005515protein binding
0.36GO:0003896DNA primase activity
0.35GO:0008270zinc ion binding
0.36EC:2.7.7 GO:0003896
sp|Q7Z6J0|SH3R1_HUMAN
E3 ubiquitin-protein ligase SH3RF1
Search
SH3RF1
0.97SH3 domain containing ring finger 1
0.83GO:0046328regulation of JNK cascade
0.78GO:0006915apoptotic process
0.62GO:2001237negative regulation of extrinsic apoptotic signaling pathway
0.62GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.40GO:0016567protein ubiquitination
0.51GO:0046872metal ion binding
0.50GO:0016874ligase activity
0.36GO:0005515protein binding
0.35GO:0016740transferase activity
0.52GO:0005829cytosol
0.43GO:0030027lamellipodium
0.42GO:0048471perinuclear region of cytoplasm
0.40GO:0005794Golgi apparatus
0.50EC:6 GO:0016874
sp|Q7Z6J2|GRASP_HUMAN
General receptor for phosphoinositides 1-associated scaffold protein
Search
CYTIP
0.92Cytohesin-interacting protein (Fragment)
0.56GO:0007165signal transduction
0.54GO:0030155regulation of cell adhesion
0.41GO:0008104protein localization
0.41GO:0071383cellular response to steroid hormone stimulus
0.37GO:0046907intracellular transport
0.37GO:0070727cellular macromolecule localization
0.37GO:0042886amide transport
0.36GO:0006351transcription, DNA-templated
0.36GO:2000112regulation of cellular macromolecule biosynthetic process
0.36GO:1903506regulation of nucleic acid-templated transcription
0.49GO:0030306ADP-ribosylation factor binding
0.48GO:0030165PDZ domain binding
0.44GO:0042802identical protein binding
0.41GO:0004879nuclear receptor activity
0.41GO:0003707steroid hormone receptor activity
0.38GO:0043565sequence-specific DNA binding
0.37GO:0008270zinc ion binding
0.54GO:0005938cell cortex
0.51GO:0005886plasma membrane
0.50GO:0005654nucleoplasm
0.50GO:0005829cytosol
0.43GO:0048471perinuclear region of cytoplasm
0.43GO:0098794postsynapse
0.42GO:0030054cell junction
0.41GO:0005641nuclear envelope lumen
0.38GO:0005769early endosome
0.30GO:0031224intrinsic component of membrane
sp|Q7Z6J4|FGD2_HUMAN
FYVE, RhoGEF and PH domain-containing protein 2
Search
FGD2
0.92FYVE, RhoGEF and PH domain-containing protein 2
0.76GO:0035023regulation of Rho protein signal transduction
0.65GO:0065009regulation of molecular function
0.53GO:0046330positive regulation of JNK cascade
0.50GO:0046847filopodium assembly
0.44GO:0030036actin cytoskeleton organization
0.43GO:0008360regulation of cell shape
0.40GO:0030035microspike assembly
0.39GO:0030032lamellipodium assembly
0.37GO:0043065positive regulation of apoptotic process
0.36GO:0007186G-protein coupled receptor signaling pathway
0.77GO:0005089Rho guanyl-nucleotide exchange factor activity
0.53GO:0046872metal ion binding
0.51GO:1901981phosphatidylinositol phosphate binding
0.33GO:0003779actin binding
0.33GO:0003924GTPase activity
0.32GO:0032550purine ribonucleoside binding
0.32GO:0019001guanyl nucleotide binding
0.32GO:0032555purine ribonucleotide binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.58GO:0001726ruffle
0.51GO:0005769early endosome
0.49GO:0030027lamellipodium
0.44GO:0005794Golgi apparatus
0.43GO:0005634nucleus
0.39GO:0030175filopodium
0.37GO:0031256leading edge membrane
0.37GO:0031253cell projection membrane
0.37GO:0005856cytoskeleton
0.37GO:0010008endosome membrane
sp|Q7Z6J6|FRMD5_HUMAN
FERM domain-containing protein 5
Search
FRMD5
0.94FERM domain-containing protein 5
0.52GO:2000146negative regulation of cell motility
0.51GO:0030334regulation of cell migration
0.50GO:0045785positive regulation of cell adhesion
0.45GO:0031032actomyosin structure organization
0.53GO:0005178integrin binding
0.53GO:0008092cytoskeletal protein binding
0.51GO:0019901protein kinase binding
0.43GO:0005200structural constituent of cytoskeleton
0.69GO:0005856cytoskeleton
0.51GO:0005912adherens junction
0.30GO:0044425membrane part
sp|Q7Z6J8|UBE3D_HUMAN
E3 ubiquitin-protein ligase E3D
Search
UBE3D
0.94Ubiquitin protein ligase E3D
0.68GO:0051865protein autoubiquitination
0.67GO:0006513protein monoubiquitination
0.66GO:0000209protein polyubiquitination
0.69GO:0044390ubiquitin-like protein conjugating enzyme binding
0.66GO:0030332cyclin binding
0.62GO:0061630ubiquitin protein ligase activity
0.53GO:0016874ligase activity
0.62GO:0000151ubiquitin ligase complex
0.36GO:0005737cytoplasm
0.53EC:6 GO:0016874
sp|Q7Z6J9|SEN54_HUMAN
tRNA-splicing endonuclease subunit Sen54
Search
TSEN54
0.96tRNA splicing endonuclease subunit 54
0.75GO:0006388tRNA splicing, via endonucleolytic cleavage and ligation
0.54GO:0090305nucleic acid phosphodiester bond hydrolysis
0.45GO:0048854brain morphogenesis
0.59GO:0000213tRNA-intron endonuclease activity
0.60GO:0000214tRNA-intron endonuclease complex
0.59EC:3.1.27.9 GO:0000213
sp|Q7Z6K1|THAP5_HUMAN
THAP domain-containing protein 5
Search
THAP5
0.97THAP domain-containing protein 5
0.59GO:0045786negative regulation of cell cycle
0.39GO:0007049cell cycle
0.37GO:0097659nucleic acid-templated transcription
0.37GO:2001141regulation of RNA biosynthetic process
0.37GO:2000112regulation of cellular macromolecule biosynthetic process
0.37GO:0010468regulation of gene expression
0.36GO:0010467gene expression
0.36GO:0034645cellular macromolecule biosynthetic process
0.62GO:0002020protease binding
0.55GO:0003677DNA binding
0.36GO:0046872metal ion binding
0.50GO:0005634nucleus
sp|Q7Z6K3|PTAR1_HUMAN
Protein prenyltransferase alpha subunit repeat-containing protein 1
Search
PTAR1
0.96Protein prenyltransferase alpha subunit repeat-containing protein 1-A
0.81GO:0097354prenylation
0.60GO:0006464cellular protein modification process
0.82GO:0008318protein prenyltransferase activity
0.44GO:1990234transferase complex
0.37GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
0.82EC:2.5.1 GO:0008318
sp|Q7Z6K4|NRARP_HUMAN
Notch-regulated ankyrin repeat-containing protein
Search
NRARP
0.52Notch-regulated ankyrin repeat-containing protein A
0.82GO:0002043blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.78GO:0001569branching involved in blood vessel morphogenesis
0.72GO:1902367negative regulation of Notch signaling pathway involved in somitogenesis
0.71GO:0060828regulation of canonical Wnt signaling pathway
0.70GO:0001938positive regulation of endothelial cell proliferation
0.70GO:0032525somite rostral/caudal axis specification
0.69GO:0007219Notch signaling pathway
0.69GO:0022407regulation of cell-cell adhesion
0.67GO:0030177positive regulation of Wnt signaling pathway
0.67GO:0045620negative regulation of lymphocyte differentiation
0.49GO:0019901protein kinase binding
0.34GO:0003677DNA binding
0.33GO:0004672protein kinase activity
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.40GO:0005913cell-cell adherens junction
0.34GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q7Z6K5|ARPIN_HUMAN
Arpin
Search
ARPIN
0.97Actin-related protein 2/3 complex inhibitor
0.85GO:0051126negative regulation of actin nucleation
0.53GO:0033058directional locomotion
0.49GO:0030336negative regulation of cell migration
0.47GO:2000393negative regulation of lamellipodium morphogenesis
0.46GO:0006886intracellular protein transport
0.46GO:0016192vesicle-mediated transport
0.34GO:0005515protein binding
0.33GO:0008565protein transporter activity
0.53GO:0030027lamellipodium
0.48GO:0030117membrane coat
0.34GO:0043231intracellular membrane-bounded organelle
sp|Q7Z6L0|PRRT2_HUMAN
Proline-rich transmembrane protein 2
Search
PRRT2
0.96Proline-rich transmembrane protein 2
0.69GO:0009607response to biotic stimulus
0.68GO:1905512regulation of short-term synaptic potentiation
0.65GO:0035544negative regulation of SNARE complex assembly
0.65GO:0031629synaptic vesicle fusion to presynaptic active zone membrane
0.47GO:0050884neuromuscular process controlling posture
0.64GO:0017075syntaxin-1 binding
0.41GO:0017124SH3 domain binding
0.34GO:0003676nucleic acid binding
0.62GO:0042734presynaptic membrane
0.61GO:0043679axon terminus
0.60GO:0008021synaptic vesicle
0.45GO:0030054cell junction
0.30GO:0016021integral component of membrane
sp|Q7Z6L1|TCPR1_HUMAN
Tectonin beta-propeller repeat-containing protein 1
Search
TECPR1
0.91Tectonin beta-propeller repeat-containing protein 1
0.58GO:0097352autophagosome maturation
0.55GO:0032266phosphatidylinositol-3-phosphate binding
0.35GO:0005515protein binding
0.58GO:0000421autophagosome membrane
0.55GO:0005765lysosomal membrane
0.47GO:0005654nucleoplasm
0.44GO:0031410cytoplasmic vesicle
0.30GO:0044425membrane part
sp|Q7Z6M1|RABEK_HUMAN
Rab9 effector protein with kelch motifs
Search
RABEPK
0.97Rab9 effector protein with kelch motifs
0.56GO:0006904vesicle docking involved in exocytosis
0.51GO:0006898receptor-mediated endocytosis
0.76GO:0010008endosome membrane
0.59GO:0032588trans-Golgi network membrane
0.54GO:0030133transport vesicle
0.50GO:0005829cytosol
sp|Q7Z6M2|FBX33_HUMAN
F-box only protein 33
Search
FBXO33
0.97F-box only protein 33
0.66GO:0016567protein ubiquitination
0.50GO:0005515protein binding
0.42GO:0003677DNA binding
0.45GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
sp|Q7Z6M3|MILR1_HUMAN
Allergin-1
Search
MILR1
0.97Mast cell immunoglobulin like receptor 1
0.86GO:0033004negative regulation of mast cell activation
0.86GO:0043303mast cell degranulation
0.86GO:0042629mast cell granule
0.38GO:0005887integral component of plasma membrane
sp|Q7Z6M4|MTEF4_HUMAN
Transcription termination factor 4, mitochondrial
Search
MTERF4
0.97Mitochondrial transcription termination factor 4
0.61GO:0006390mitochondrial transcription
0.57GO:0043010camera-type eye development
0.56GO:0007507heart development
0.56GO:0042255ribosome assembly
0.56GO:0006626protein targeting to mitochondrion
0.55GO:2001141regulation of RNA biosynthetic process
0.55GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.46GO:0008380RNA splicing
0.38GO:0006364rRNA processing
0.69GO:0003690double-stranded DNA binding
0.51GO:0019843rRNA binding
0.49GO:0003727single-stranded RNA binding
0.35GO:0004672protein kinase activity
0.35GO:0005515protein binding
0.34GO:0004930G-protein coupled receptor activity
0.34GO:0030554adenyl nucleotide binding
0.34GO:0097367carbohydrate derivative binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.57GO:0005762mitochondrial large ribosomal subunit
0.52GO:0005829cytosol
0.34GO:0005730nucleolus
0.34GO:0005801cis-Golgi network
0.33GO:0016456X chromosome located dosage compensation complex, transcription activating
0.32GO:0044545NSL complex
0.32GO:0005705polytene chromosome interband
0.32GO:0072487MSL complex
0.32GO:0012505endomembrane system
0.32GO:0005854nascent polypeptide-associated complex
0.32EC:3.4.24 GO:0004222
sp|Q7Z6P3|RAB44_HUMAN
Ras-related protein Rab-44
Search
RAB44
0.78RAB44, member RAS oncogene family
0.40GO:0048227plasma membrane to endosome transport
0.40GO:0043312neutrophil degranulation
0.38GO:0030100regulation of endocytosis
0.35GO:0007050cell cycle arrest
0.35GO:0071901negative regulation of protein serine/threonine kinase activity
0.34GO:0001702gastrulation with mouth forming second
0.34GO:0001525angiogenesis
0.34GO:0098609cell-cell adhesion
0.34GO:0007165signal transduction
0.34GO:0034765regulation of ion transmembrane transport
0.68GO:0003924GTPase activity
0.66GO:0005525GTP binding
0.41GO:0005509calcium ion binding
0.40GO:0019003GDP binding
0.35GO:0004861cyclin-dependent protein serine/threonine kinase inhibitor activity
0.34GO:0038023signaling receptor activity
0.34GO:0005249voltage-gated potassium channel activity
0.33GO:0099600transmembrane receptor activity
0.33GO:0004673protein histidine kinase activity
0.33GO:0004767sphingomyelin phosphodiesterase activity
0.42GO:0031410cytoplasmic vesicle
0.40GO:0012505endomembrane system
0.40GO:0005766primary lysosome
0.39GO:0005811lipid droplet
0.38GO:0005765lysosomal membrane
0.38GO:0012506vesicle membrane
0.36GO:0005886plasma membrane
0.34GO:0005576extracellular region
0.33GO:0031225anchored component of membrane
0.33GO:0098793presynapse
0.33EC:2.7.13.3 GO:0004673
0.33KEGG:R02541 GO:0004767
sp|Q7Z6R9|AP2D_HUMAN
Transcription factor AP-2-delta
Search
TFAP2D
0.97Transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
0.63GO:0061379inferior colliculus development
0.58GO:0043524negative regulation of neuron apoptotic process
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.53GO:1902680positive regulation of RNA biosynthetic process
0.47GO:0042127regulation of cell proliferation
0.38GO:0035213clypeo-labral disc development
0.38GO:0016348imaginal disc-derived leg joint morphogenesis
0.38GO:0002121inter-male aggressive behavior
0.61GO:0003700DNA binding transcription factor activity
0.56GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding
0.34GO:0005515protein binding
0.34GO:0000987proximal promoter sequence-specific DNA binding
0.33GO:0050662coenzyme binding
0.30GO:0003824catalytic activity
0.61GO:0005634nucleus
0.53GO:0005667transcription factor complex
0.30GO:0016020membrane
sp|Q7Z6V5|ADAT2_HUMAN
tRNA-specific adenosine deaminase 2
Search
ADAT2
0.94tRNA-specific adenosine deaminase 2
0.65GO:0002100tRNA wobble adenosine to inosine editing
0.66GO:0008251tRNA-specific adenosine deaminase activity
0.62GO:0008270zinc ion binding
0.33GO:0005515protein binding
0.52GO:0052718tRNA-specific adenosine-34 deaminase complex
0.34GO:0005654nucleoplasm
0.30GO:0016021integral component of membrane
0.66EC:3.5.4 GO:0008251
sp|Q7Z6W1|TMCO2_HUMAN
Transmembrane and coiled-coil domain-containing protein 2
Search
0.33GO:0003676nucleic acid binding
0.38GO:0005634nucleus
0.30GO:0016021integral component of membrane
sp|Q7Z6W7|DNJB7_HUMAN
DnaJ homolog subfamily B member 7
Search
DNAJB6
0.79DnaJ like protein subfamily B member 7
0.62GO:0090084negative regulation of inclusion body assembly
0.60GO:0045109intermediate filament organization
0.59GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.56GO:0032781positive regulation of ATPase activity
0.55GO:0060715syncytiotrophoblast cell differentiation involved in labyrinthine layer development
0.54GO:0060710chorio-allantoic fusion
0.53GO:0060717chorion development
0.53GO:0032880regulation of protein localization
0.50GO:0006457protein folding
0.49GO:0030198extracellular matrix organization
0.72GO:0051087chaperone binding
0.57GO:0001671ATPase activator activity
0.55GO:0031072heat shock protein binding
0.52GO:0051082unfolded protein binding
0.41GO:0042802identical protein binding
0.40GO:0003677DNA binding
0.38GO:0044183protein binding involved in protein folding
0.34GO:0003735structural constituent of ribosome
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.62GO:0030018Z disc
0.61GO:0048471perinuclear region of cytoplasm
0.51GO:0005634nucleus
0.50GO:0005829cytosol
0.49GO:0031974membrane-enclosed lumen
0.44GO:0044446intracellular organelle part
0.36GO:0070062extracellular exosome
0.34GO:0005840ribosome
0.30GO:0016020membrane
sp|Q7Z6Z6|PLPL5_HUMAN
Patatin-like phospholipase domain-containing protein 5
Search
0.88Patatin like phospholipase domain containing 5
0.70GO:0016042lipid catabolic process
0.70GO:0010898positive regulation of triglyceride catabolic process
0.55GO:0006641triglyceride metabolic process
0.51GO:0034389lipid particle organization
0.51GO:0010891negative regulation of sequestering of triglyceride
0.50GO:0055088lipid homeostasis
0.47GO:0019915lipid storage
0.46GO:0044248cellular catabolic process
0.42GO:0036155acylglycerol acyl-chain remodeling
0.39GO:0046463acylglycerol biosynthetic process
0.67GO:0004806triglyceride lipase activity
0.41GO:0051265diolein transacylation activity
0.41GO:0051264mono-olein transacylation activity
0.41GO:0035727lysophosphatidic acid binding
0.41GO:0036042long-chain fatty acyl-CoA binding
0.39GO:0004623phospholipase A2 activity
0.39GO:0042171lysophosphatidic acid acyltransferase activity
0.34GO:0005515protein binding
0.55GO:0005811lipid droplet
0.43GO:0005829cytosol
0.43GO:0005654nucleoplasm
0.34GO:0005788endoplasmic reticulum lumen
0.34GO:0005886plasma membrane
0.33GO:0005789endoplasmic reticulum membrane
0.30GO:0016021integral component of membrane
0.67EC:3.1.1.3 GO:0004806
sp|Q7Z6Z7|HUWE1_HUMAN
E3 ubiquitin-protein ligase HUWE1
Search
HUWE1
0.48HECT, UBA and WWE domain containing 1
0.72GO:0016567protein ubiquitination
0.55GO:1903955positive regulation of protein targeting to mitochondrion
0.50GO:0016570histone modification
0.49GO:0006284base-excision repair
0.46GO:0006511ubiquitin-dependent protein catabolic process
0.38GO:0043312neutrophil degranulation
0.38GO:0030154cell differentiation
0.32GO:0006355regulation of transcription, DNA-templated
0.73GO:0004842ubiquitin-protein transferase activity
0.49GO:0016874ligase activity
0.47GO:0061659ubiquitin-like protein ligase activity
0.46GO:0008270zinc ion binding
0.35GO:0003677DNA binding
0.35GO:0005515protein binding
0.34GO:0003723RNA binding
0.32GO:0003700DNA binding transcription factor activity
0.49GO:0005654nucleoplasm
0.49GO:0005829cytosol
0.38GO:1904813ficolin-1-rich granule lumen
0.38GO:0034774secretory granule lumen
0.37GO:0070062extracellular exosome
0.30GO:0016020membrane
0.49EC:6 GO:0016874
0.73KEGG:R03876 GO:0004842
sp|Q7Z713|ANR37_HUMAN
Ankyrin repeat domain-containing protein 37
Search
ANKRD37
0.97LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 37
0.42GO:0033146regulation of intracellular estrogen receptor signaling pathway
0.36GO:0006508proteolysis
0.42GO:0071567UFM1 hydrolase activity
0.39GO:0016790thiolester hydrolase activity
0.36GO:0005515protein binding
0.68GO:0005829cytosol
0.61GO:0005634nucleus
0.60GO:0005739mitochondrion
0.38GO:0005783endoplasmic reticulum
0.39EC:3.1.2 GO:0016790
sp|Q7Z736|PKHH3_HUMAN
Pleckstrin homology domain-containing family H member 3
Search
PLEKHH3
0.80Unconventional myosin-X
0.57GO:0007165signal transduction
0.49GO:0007018microtubule-based movement
0.37GO:0051489regulation of filopodium assembly
0.36GO:0022409positive regulation of cell-cell adhesion
0.35GO:0008360regulation of cell shape
0.49GO:0003777microtubule motor activity
0.49GO:0008017microtubule binding
0.49GO:0003779actin binding
0.41GO:0032559adenyl ribonucleotide binding
0.40GO:0008144drug binding
0.40GO:0035639purine ribonucleoside triphosphate binding
0.37GO:0030507spectrin binding
0.32GO:0003676nucleic acid binding
0.68GO:0005856cytoskeleton
0.43GO:0043234protein complex
0.42GO:0044446intracellular organelle part
0.38GO:0005615extracellular space
0.36GO:0030175filopodium
0.36GO:0043025neuronal cell body
0.36GO:0043005neuron projection
0.35GO:0005829cytosol
0.35GO:0031974membrane-enclosed lumen
0.34GO:0005634nucleus
sp|Q7Z739|YTHD3_HUMAN
YTH domain-containing family protein 3
Search
YTHDF3
0.97LOW QUALITY PROTEIN: YTH domain-containing family protein 3
0.40GO:0061157mRNA destabilization
0.38GO:0045727positive regulation of translation
0.37GO:0006446regulation of translational initiation
0.58GO:0003723RNA binding
0.38GO:0043022ribosome binding
0.33GO:0005515protein binding
0.32GO:0003677DNA binding
0.36GO:0005829cytosol
sp|Q7Z745|MRO2B_HUMAN
Maestro heat-like repeat-containing protein family member 2B
Search
MROH2B
0.97LOW QUALITY PROTEIN: maestro heat-like repeat-containing protein family member 2B
0.86GO:0010737protein kinase A signaling
0.46GO:0007283spermatogenesis
0.43GO:0030154cell differentiation
0.37GO:0005515protein binding
0.86GO:0097225sperm midpiece
0.84GO:0001669acrosomal vesicle
sp|Q7Z769|S35E3_HUMAN
Solute carrier family 35 member E3
Search
SLC35E3
0.96Siah E3 ubiquitin protein ligase family member 3
0.30GO:0044425membrane part
sp|Q7Z794|K2C1B_HUMAN
Keratin, type II cytoskeletal 1b
Search
0.94Keratin, type II cytoskeletal 2 epidermal
0.53GO:0043588skin development
0.52GO:0018149peptide cross-linking
0.48GO:0001867complement activation, lectin pathway
0.48GO:0033561regulation of water loss via skin
0.48GO:0032980keratinocyte activation
0.47GO:0045104intermediate filament cytoskeleton organization
0.47GO:0050728negative regulation of inflammatory response
0.47GO:0008544epidermis development
0.47GO:0051546keratinocyte migration
0.46GO:0043616keratinocyte proliferation
0.62GO:0005198structural molecule activity
0.42GO:0030246carbohydrate binding
0.41GO:0005515protein binding
0.35GO:0044877macromolecular complex binding
0.33GO:0004872receptor activity
0.83GO:0045095keratin filament
0.53GO:0001533cornified envelope
0.40GO:0070062extracellular exosome
0.36GO:0072562blood microparticle
0.36GO:0031012extracellular matrix
0.36GO:0005829cytosol
0.35GO:0043231intracellular membrane-bounded organelle
0.35GO:1904813ficolin-1-rich granule lumen
0.33GO:0036338viral membrane
sp|Q7Z7A1|CNTRL_HUMAN
Centriolin
Search
CNTRL
0.97Centriolin
0.75GO:0000278mitotic cell cycle
0.67GO:0051301cell division
0.41GO:0060976coronary vasculature development
0.41GO:0035904aorta development
0.40GO:0003281ventricular septum development
0.38GO:0097711ciliary basal body-plasma membrane docking
0.37GO:0044839cell cycle G2/M phase transition
0.36GO:0010389regulation of G2/M transition of mitotic cell cycle
0.36GO:0018108peptidyl-tyrosine phosphorylation
0.36GO:0004713protein tyrosine kinase activity
0.34GO:0005515protein binding
0.61GO:0120103centriolar subdistal appendage
0.55GO:0005813centrosome
0.49GO:0005829cytosol
0.41GO:0097431mitotic spindle pole
0.39GO:0090543Flemming body
0.39GO:0048471perinuclear region of cytoplasm
0.30GO:0016020membrane
0.36EC:2.7.10 GO:0004713
sp|Q7Z7A3|CTU1_HUMAN
Cytoplasmic tRNA 2-thiolation protein 1
Search
NCS6
0.73Cytosolic thiouridylase subunit 1
0.78GO:0034227tRNA thio-modification
0.78GO:0032447protein urmylation
0.76GO:0002098tRNA wobble uridine modification
0.34GO:0006508proteolysis
0.34GO:0040025vulval development
0.34GO:0048599oocyte development
0.34GO:0007283spermatogenesis
0.34GO:0048598embryonic morphogenesis
0.32GO:0043043peptide biosynthetic process
0.32GO:0009059macromolecule biosynthetic process
0.69GO:0000049tRNA binding
0.59GO:0016779nucleotidyltransferase activity
0.35GO:0004252serine-type endopeptidase activity
0.34GO:0005515protein binding
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0016783sulfurtransferase activity
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.61GO:0002144cytosolic tRNA wobble base thiouridylase complex
0.42GO:0005739mitochondrion
0.30GO:0016020membrane
0.59EC:2.7.7 GO:0016779
sp|Q7Z7A4|PXK_HUMAN
PX domain-containing protein kinase-like protein
Search
PXK
0.96PX domain containing serine/threonine kinase like
0.62GO:0006468protein phosphorylation
0.52GO:0006954inflammatory response
0.38GO:0043271negative regulation of ion transport
0.38GO:0050804modulation of chemical synaptic transmission
0.38GO:0032780negative regulation of ATPase activity
0.34GO:0090501RNA phosphodiester bond hydrolysis
0.34GO:0008033tRNA processing
0.75GO:0035091phosphatidylinositol binding
0.67GO:0003779actin binding
0.62GO:0004672protein kinase activity
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.38GO:0008022protein C-terminus binding
0.34GO:0004540ribonuclease activity
0.51GO:0005815microtubule organizing center
0.48GO:0005829cytosol
0.42GO:0005886plasma membrane
0.35GO:0005634nucleus
0.34GO:0043234protein complex
sp|Q7Z7B0|FLIP1_HUMAN
Filamin-A-interacting protein 1
Search
FILIP1
0.92Filamin-A-interacting protein 1
0.33GO:1902600hydrogen ion transmembrane transport
0.33GO:0022900electron transport chain
0.33GO:0016675oxidoreductase activity, acting on a heme group of donors
0.33GO:0015002heme-copper terminal oxidase activity
0.33GO:0015078hydrogen ion transmembrane transporter activity
0.33GO:0009055electron transfer activity
0.68GO:0015629actin cytoskeleton
0.68GO:0005730nucleolus
0.52GO:0005886plasma membrane
0.42GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
0.33EC:1.9 GO:0016675
sp|Q7Z7B1|PIGW_HUMAN
Phosphatidylinositol-glycan biosynthesis class W protein
Search
PIGW
0.91Phosphatidylinositol-glycan biosynthesis class W protein (Fragment)
0.78GO:0006506GPI anchor biosynthetic process
0.56GO:0072659protein localization to plasma membrane
0.33GO:0006486protein glycosylation
0.32GO:0006897endocytosis
0.63GO:0016746transferase activity, transferring acyl groups
0.34GO:0008378galactosyltransferase activity
0.32GO:0004040amidase activity
0.66GO:0005789endoplasmic reticulum membrane
0.30GO:0031224intrinsic component of membrane
0.63EC:2.3 GO:0016746
sp|Q7Z7B7|DB132_HUMAN
Beta-defensin 132
Search
DEFB132
0.64Beta-defensin
0.79GO:0045087innate immune response
0.77GO:0042742defense response to bacterium
0.68GO:0031640killing of cells of other organism
0.78GO:0061827sperm head
0.66GO:0005576extracellular region
0.51GO:0009986cell surface
sp|Q7Z7B8|DB128_HUMAN
Beta-defensin 128
Search
DEFB128
0.63Beta-defensin
0.79GO:0045087innate immune response
0.78GO:0042742defense response to bacterium
0.66GO:0031640killing of cells of other organism
0.66GO:0005576extracellular region
0.50GO:0009986cell surface
sp|Q7Z7C7|STRA8_HUMAN
Stimulated by retinoic acid gene 8 protein homolog
Search
STRA8
0.95LOW QUALITY PROTEIN: stimulated by retinoic acid gene 8 protein homolog
0.85GO:0071300cellular response to retinoic acid
0.78GO:0051321meiotic cell cycle
0.72GO:0048133male germ-line stem cell asymmetric division
0.61GO:0045944positive regulation of transcription by RNA polymerase II
0.42GO:0048477oogenesis
0.38GO:0006260DNA replication
0.37GO:0006351transcription, DNA-templated
0.64GO:0046983protein dimerization activity
0.52GO:0005634nucleus
0.43GO:0005737cytoplasm
sp|Q7Z7C8|TAF8_HUMAN
Transcription initiation factor TFIID subunit 8
Search
TAF8
0.93Transcription initiation factor TFIID subunit 8
0.59GO:0006413translational initiation
0.55GO:0051457maintenance of protein location in nucleus
0.54GO:0045598regulation of fat cell differentiation
0.53GO:0001833inner cell mass cell proliferation
0.49GO:0045893positive regulation of transcription, DNA-templated
0.39GO:0030154cell differentiation
0.36GO:0006351transcription, DNA-templated
0.36GO:0006030chitin metabolic process
0.35GO:0016073snRNA metabolic process
0.35GO:0005975carbohydrate metabolic process
0.70GO:0046982protein heterodimerization activity
0.59GO:0003743translation initiation factor activity
0.37GO:0008061chitin binding
0.35GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds
0.74GO:0005669transcription factor TFIID complex
0.52GO:0048471perinuclear region of cytoplasm
0.35GO:0005576extracellular region
0.30GO:0031224intrinsic component of membrane
0.35EC:3.2.1 GO:0004553
sp|Q7Z7D3|VTCN1_HUMAN
V-set domain-containing T-cell activation inhibitor 1
Search
VTCN1
0.97V-set domain-containing T-cell activation inhibitor 1
0.71GO:1900042positive regulation of interleukin-2 secretion
0.70GO:0072643interferon-gamma secretion
0.70GO:0072602interleukin-4 secretion
0.68GO:0001562response to protozoan
0.67GO:0042130negative regulation of T cell proliferation
0.66GO:0042102positive regulation of T cell proliferation
0.61GO:0043066negative regulation of apoptotic process
0.44GO:0002250adaptive immune response
0.57GO:0005102receptor binding
0.64GO:0009897external side of plasma membrane
0.40GO:0031225anchored component of membrane
0.30GO:0016021integral component of membrane
sp|Q7Z7E8|UB2Q1_HUMAN
Ubiquitin-conjugating enzyme E2 Q1
Search
UBE2Q1
0.90Ubiquitin-conjugating enzyme E2Q family member 2
0.85GO:0070459prolactin secretion
0.82GO:0001967suckling behavior
0.81GO:0007617mating behavior
0.80GO:0007566embryo implantation
0.78GO:0009566fertilization
0.74GO:0061458reproductive system development
0.72GO:0016567protein ubiquitination
0.83GO:0061631ubiquitin conjugating enzyme activity
0.39GO:0032559adenyl ribonucleotide binding
0.38GO:0008144drug binding
0.38GO:0035639purine ribonucleoside triphosphate binding
0.37GO:0005515protein binding
0.45GO:0030175filopodium
0.42GO:0005829cytosol
0.39GO:0005634nucleus
sp|Q7Z7F0|K0907_HUMAN
UPF0469 protein KIAA0907
Search
KHDC4
0.97KH homology domain-containing protein 4
0.77GO:0006376mRNA splice site selection
0.59GO:0003723RNA binding
0.52GO:0005515protein binding
0.71GO:0005681spliceosomal complex
0.50GO:0019013viral nucleocapsid
0.47GO:0005737cytoplasm
sp|Q7Z7F7|RM55_HUMAN
39S ribosomal protein L55, mitochondrial
Search
MRPL55
0.97Mitochondrial ribosomal protein L55
0.39GO:0070126mitochondrial translational termination
0.38GO:0070125mitochondrial translational elongation
0.34GO:0016310phosphorylation
0.64GO:0003735structural constituent of ribosome
0.34GO:0016301kinase activity
0.82GO:0005762mitochondrial large ribosomal subunit
0.36GO:0031966mitochondrial membrane
0.36GO:0019866organelle inner membrane
sp|Q7Z7G0|TARSH_HUMAN
Target of Nesh-SH3
Search
ABI3BP
0.79ABI family, member 3 (NESH) binding protein b
0.84GO:0010811positive regulation of cell-substrate adhesion
0.80GO:0030198extracellular matrix organization
0.83GO:0005518collagen binding
0.82GO:0008201heparin binding
0.86GO:0005614interstitial matrix
0.70GO:0005615extracellular space
sp|Q7Z7G1|CLNK_HUMAN
Cytokine-dependent hematopoietic cell linker
Search
CLNK
0.97Cytokine-dependent hematopoietic cell linker
0.70GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
0.59GO:0035556intracellular signal transduction
0.58GO:0006955immune response
0.50GO:0043551regulation of phosphatidylinositol 3-kinase activity
0.41GO:0009967positive regulation of signal transduction
0.40GO:0046856phosphatidylinositol dephosphorylation
0.37GO:0042127regulation of cell proliferation
0.37GO:0045659negative regulation of neutrophil differentiation
0.37GO:0016310phosphorylation
0.37GO:0045409negative regulation of interleukin-6 biosynthetic process
0.51GO:0035014phosphatidylinositol 3-kinase regulator activity
0.43GO:0005070SH3/SH2 adaptor activity
0.37GO:0051425PTB domain binding
0.37GO:0016301kinase activity
0.37GO:0004445inositol-polyphosphate 5-phosphatase activity
0.36GO:0034594phosphatidylinositol trisphosphate phosphatase activity
0.36GO:0019900kinase binding
0.35GO:0017124SH3 domain binding
0.33GO:0043560insulin receptor substrate binding
0.33GO:0046872metal ion binding
0.49GO:0005942phosphatidylinositol 3-kinase complex
0.44GO:0005622intracellular
0.30GO:0016021integral component of membrane
0.37EC:3.1.3.56 GO:0004445
sp|Q7Z7G2|CPLX4_HUMAN
Complexin-4
Search
CPLX4
0.97LOW QUALITY PROTEIN: complexin-4
0.76GO:0006836neurotransmitter transport
0.64GO:0046928regulation of neurotransmitter secretion
0.50GO:0030073insulin secretion
0.49GO:0017156calcium ion regulated exocytosis
0.48GO:0097480establishment of synaptic vesicle localization
0.48GO:0099504synaptic vesicle cycle
0.48GO:0099003vesicle-mediated transport in synapse
0.48GO:0099643signal release from synapse
0.48GO:0099531presynaptic process involved in chemical synaptic transmission
0.44GO:0046907intracellular transport
0.84GO:0019905syntaxin binding
0.47GO:0005326neurotransmitter transporter activity
0.35GO:0005537mannose binding
0.33GO:0003677DNA binding
0.58GO:0045202synapse
0.48GO:0097458neuron part
0.43GO:0005829cytosol
0.39GO:0120038plasma membrane bounded cell projection part
0.39GO:0005886plasma membrane
0.38GO:0030054cell junction
0.35GO:0005634nucleus
0.30GO:0016021integral component of membrane
sp|Q7Z7G8|VP13B_HUMAN
Vacuolar protein sorting-associated protein 13B
Search
VPS13B
0.84Vacuolar protein sorting-associated protein 13B
0.30GO:0045184establishment of protein localization
0.30GO:0042886amide transport
0.30GO:0071702organic substance transport
0.30GO:0044425membrane part
sp|Q7Z7H3|CATIP_HUMAN
Ciliogenesis-associated TTC17-interacting protein
Search
CATIP
0.97ciliogenesis-associated TTC17-interacting protein isoform X1
0.83GO:0030041actin filament polymerization
0.78GO:0044782cilium organization
0.47GO:0061371determination of heart left/right asymmetry
0.45GO:0120031plasma membrane bounded cell projection assembly
0.43GO:0070925organelle assembly
0.39GO:0019243methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
0.39GO:0004416hydroxyacylglutathione hydrolase activity
0.38GO:0005515protein binding
0.71GO:0015629actin cytoskeleton
0.60GO:0005634nucleus
0.54GO:0005886plasma membrane
0.48GO:0005737cytoplasm
0.39EC:3.1.2.6 GO:0004416
sp|Q7Z7H5|TMED4_HUMAN
Transmembrane emp24 domain-containing protein 4
Search
TMED4
0.92Endoplasmic reticulum stress-response protein 25
0.52GO:0048205COPI coating of Golgi vesicle
0.48GO:0007030Golgi organization
0.46GO:0010638positive regulation of organelle organization
0.37GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.37GO:0033036macromolecule localization
0.37GO:0042886amide transport
0.36GO:0071702organic substance transport
0.36GO:0034498early endosome to Golgi transport
0.34GO:0007165signal transduction
0.34GO:0006890retrograde vesicle-mediated transport, Golgi to ER
0.48GO:0019905syntaxin binding
0.35GO:0004871signal transducer activity
0.34GO:0005319lipid transporter activity
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0003676nucleic acid binding
0.67GO:0005789endoplasmic reticulum membrane
0.48GO:0005793endoplasmic reticulum-Golgi intermediate compartment
0.45GO:0000139Golgi membrane
0.39GO:0070062extracellular exosome
0.35GO:0030133transport vesicle
0.34GO:0030136clathrin-coated vesicle
0.34GO:0099503secretory vesicle
0.34GO:0005798Golgi-associated vesicle
0.30GO:0016021integral component of membrane
sp|Q7Z7H8|RM10_HUMAN
39S ribosomal protein L10, mitochondrial
Search
MRPL10
0.97Mitochondrial ribosomal protein L10
0.64GO:0042254ribosome biogenesis
0.49GO:0032543mitochondrial translation
0.35GO:0006415translational termination
0.35GO:0006414translational elongation
0.35GO:0006869lipid transport
0.33GO:0006508proteolysis
0.43GO:0003735structural constituent of ribosome
0.35GO:0016805dipeptidase activity
0.35GO:0003723RNA binding
0.34GO:0005515protein binding
0.59GO:0005762mitochondrial large ribosomal subunit
0.51GO:0005654nucleoplasm
0.35GO:0031966mitochondrial membrane
0.35GO:0019866organelle inner membrane
0.35EC:3.4.13 GO:0016805
sp|Q7Z7J5|DPPA2_HUMAN
Developmental pluripotency-associated protein 2
Search
DPPA2
0.97Developmental pluripotency-associated protein 2
0.52GO:0060484lung-associated mesenchyme development
0.47GO:0019827stem cell population maintenance
0.46GO:2000648positive regulation of stem cell proliferation
0.45GO:0031060regulation of histone methylation
0.42GO:0006351transcription, DNA-templated
0.42GO:2000112regulation of cellular macromolecule biosynthetic process
0.42GO:1903506regulation of nucleic acid-templated transcription
0.42GO:0010468regulation of gene expression
0.43GO:0003682chromatin binding
0.41GO:0005515protein binding
0.61GO:0005634nucleus
0.37GO:0043233organelle lumen
0.35GO:0044446intracellular organelle part
sp|Q7Z7J7|LHPL4_HUMAN
Lipoma HMGIC fusion partner-like 4 protein
Search
LHFPL4
0.96LHFPL tetraspan subfamily member 4
0.34GO:0050974detection of mechanical stimulus involved in sensory perception
0.30GO:0031224intrinsic component of membrane
sp|Q7Z7J9|CK2N1_HUMAN
Calcium/calmodulin-dependent protein kinase II inhibitor 1
Search
CAMK2N2
0.95Calcium/calmodulin dependent protein kinase II inhibitor 1
0.81GO:0006469negative regulation of protein kinase activity
0.51GO:0070373negative regulation of ERK1 and ERK2 cascade
0.49GO:1904029regulation of cyclin-dependent protein kinase activity
0.49GO:0008285negative regulation of cell proliferation
0.48GO:0016310phosphorylation
0.48GO:0045786negative regulation of cell cycle
0.47GO:0045861negative regulation of proteolysis
0.46GO:0010628positive regulation of gene expression
0.35GO:0007268chemical synaptic transmission
0.35GO:0048167regulation of synaptic plasticity
0.83GO:0004860protein kinase inhibitor activity
0.64GO:0010858calcium-dependent protein kinase regulator activity
0.54GO:0019901protein kinase binding
0.50GO:0016301kinase activity
0.50GO:0014069postsynaptic density
0.48GO:0005813centrosome
0.42GO:0005634nucleus
0.40GO:0045211postsynaptic membrane
0.40GO:0043005neuron projection
0.39GO:0030054cell junction
0.39GO:0043025neuronal cell body
0.38GO:0120038plasma membrane bounded cell projection part
0.38GO:0005829cytosol
sp|Q7Z7K0|COXM1_HUMAN
COX assembly mitochondrial protein homolog
Search
CMC1
0.66COX assembly mitochondrial protein homolog
0.35GO:0033617mitochondrial respiratory chain complex IV assembly
0.34GO:0015991ATP hydrolysis coupled proton transport
0.32GO:0007165signal transduction
0.35GO:0046872metal ion binding
0.34GO:0046961proton-transporting ATPase activity, rotational mechanism
0.33GO:0005230extracellular ligand-gated ion channel activity
0.33GO:0004888transmembrane signaling receptor activity
0.60GO:0005739mitochondrion
0.35GO:0031970organelle envelope lumen
0.34GO:0000221vacuolar proton-transporting V-type ATPase, V1 domain
0.30GO:0016021integral component of membrane
sp|Q7Z7K2|ZN467_HUMAN
Zinc finger protein 467
Search
ZNF467
0.77Zinc finger protein 467
0.51GO:1903506regulation of nucleic acid-templated transcription
0.51GO:2000112regulation of cellular macromolecule biosynthetic process
0.51GO:0010468regulation of gene expression
0.48GO:1902680positive regulation of RNA biosynthetic process
0.47GO:1901216positive regulation of neuron death
0.43GO:0006366transcription by RNA polymerase II
0.42GO:1902679negative regulation of RNA biosynthetic process
0.51GO:0003676nucleic acid binding
0.48GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.46GO:0046872metal ion binding
0.44GO:0031625ubiquitin protein ligase binding
0.48GO:0005634nucleus
0.43GO:0031974membrane-enclosed lumen
0.40GO:0043232intracellular non-membrane-bounded organelle
0.40GO:0044446intracellular organelle part
0.36GO:0005737cytoplasm
sp|Q7Z7K6|CENPV_HUMAN
Centromere protein V
Search
CENPV
0.86Centromere protein V
0.56GO:0031508pericentric heterochromatin assembly
0.52GO:0032467positive regulation of cytokinesis
0.51GO:0001667ameboidal-type cell migration
0.49GO:0033044regulation of chromosome organization
0.36GO:0051301cell division
0.36GO:0007049cell cycle
0.30GO:0008152metabolic process
0.71GO:0016846carbon-sulfur lyase activity
0.52GO:0051233spindle midzone
0.50GO:0000776kinetochore
0.43GO:0005634nucleus
0.38GO:0000779condensed chromosome, centromeric region
0.33GO:0005737cytoplasm
0.71EC:4.4 GO:0016846
sp|Q7Z7L1|SLN11_HUMAN
Schlafen family member 11
Search
0.97Schlafen family member 10 homologue, CAST/EiJ strain specific
0.61GO:2000134negative regulation of G1/S transition of mitotic cell cycle
0.56GO:0051607defense response to virus
0.46GO:0036345platelet maturation
0.41GO:0016075rRNA catabolic process
0.41GO:0006402mRNA catabolic process
0.40GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0000049tRNA binding
0.40GO:0043022ribosome binding
0.40GO:0004521endoribonuclease activity
0.54GO:0005634nucleus
0.47GO:0016235aggresome
0.42GO:0005829cytosol
0.42GO:0031974membrane-enclosed lumen
0.39GO:0044446intracellular organelle part
0.30GO:0016020membrane
sp|Q7Z7L7|ZER1_HUMAN
Protein zer-1 homolog
Search
ZER1
0.97Zyg-11 protein B
0.80GO:0051438regulation of ubiquitin-protein transferase activity
0.71GO:0016567protein ubiquitination
0.39GO:0006468protein phosphorylation
0.72GO:0004842ubiquitin-protein transferase activity
0.41GO:0004674protein serine/threonine kinase activity
0.85GO:0031462Cul2-RING ubiquitin ligase complex
0.30GO:0031224intrinsic component of membrane
0.41EC:2.7.11 GO:0004674
0.72KEGG:R03876 GO:0004842
sp|Q7Z7L8|CK096_HUMAN
Uncharacterized protein C11orf96
Search
0.54GO:0035552oxidative single-stranded DNA demethylation
0.52GO:0006307DNA dealkylation involved in DNA repair
0.49GO:0000160phosphorelay signal transduction system
0.39GO:0034220ion transmembrane transport
0.54GO:0042302structural constituent of cuticle
0.48GO:0051213dioxygenase activity
0.47GO:0003779actin binding
0.42GO:0005216ion channel activity
0.45GO:0005581collagen trimer
0.39GO:0005622intracellular
0.30GO:0016021integral component of membrane
sp|Q7Z7L9|ZSCA2_HUMAN
Zinc finger and SCAN domain-containing protein 2
Search
0.55Zinc finger and SCAN domain-containing protein 2
0.52GO:1903506regulation of nucleic acid-templated transcription
0.52GO:2000112regulation of cellular macromolecule biosynthetic process
0.52GO:0010468regulation of gene expression
0.40GO:0006351transcription, DNA-templated
0.34GO:0044789modulation by host of viral release from host cell
0.34GO:1902188positive regulation of viral release from host cell
0.34GO:0044794positive regulation by host of viral process
0.33GO:0032259methylation
0.30GO:0030154cell differentiation
0.30GO:0048232male gamete generation
0.50GO:0003700DNA binding transcription factor activity
0.49GO:0003676nucleic acid binding
0.47GO:0046872metal ion binding
0.33GO:0008168methyltransferase activity
0.48GO:0005634nucleus
0.33EC:2.1.1 GO:0008168
sp|Q7Z7M0|MEGF8_HUMAN
Multiple epidermal growth factor-like domains protein 8
Search
MEGF8
0.68Multiple EGF like domains 8
0.66GO:0060972left/right pattern formation
0.66GO:0097155fasciculation of sensory neuron axon
0.65GO:0048842positive regulation of axon extension involved in axon guidance
0.65GO:0055113epiboly involved in gastrulation with mouth forming second
0.64GO:0071907determination of digestive tract left/right asymmetry
0.63GO:0042074cell migration involved in gastrulation
0.61GO:0003143embryonic heart tube morphogenesis
0.61GO:0061371determination of heart left/right asymmetry
0.61GO:0030509BMP signaling pathway
0.61GO:0097094craniofacial suture morphogenesis
0.67GO:0005509calcium ion binding
0.38GO:0005515protein binding
0.32GO:0003676nucleic acid binding
0.48GO:0005634nucleus
0.42GO:0070062extracellular exosome
0.30GO:0016020membrane
sp|Q7Z7M1|AGRD2_HUMAN
Adhesion G-protein coupled receptor D2
Search
ADGRD2
0.97Adhesion G-protein coupled receptor D2
0.71GO:0007166cell surface receptor signaling pathway
0.70GO:0007186G-protein coupled receptor signaling pathway
0.34GO:0048168regulation of neuronal synaptic plasticity
0.33GO:0042752regulation of circadian rhythm
0.33GO:0019933cAMP-mediated signaling
0.33GO:0016525negative regulation of angiogenesis
0.33GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.32GO:0015074DNA integration
0.31GO:0006508proteolysis
0.71GO:0004930G-protein coupled receptor activity
0.39GO:0030246carbohydrate binding
0.34GO:0046872metal ion binding
0.32GO:0004252serine-type endopeptidase activity
0.32GO:0005515protein binding
0.31GO:0003676nucleic acid binding
0.35GO:0005576extracellular region
0.32GO:0005886plasma membrane
0.31GO:0005622intracellular
0.30GO:0016021integral component of membrane
0.32EC:3.4.21 GO:0004252
sp|Q7Z7M8|B3GN8_HUMAN
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
Search
B3GNT8
0.57Hexosyltransferase
0.74GO:0006486protein glycosylation
0.71GO:0030311poly-N-acetyllactosamine biosynthetic process
0.33GO:0006508proteolysis
0.81GO:0008378galactosyltransferase activity
0.71GO:0016262protein N-acetylglucosaminyltransferase activity
0.33GO:0017171serine hydrolase activity
0.33GO:0070011peptidase activity, acting on L-amino acid peptides
0.74GO:0000139Golgi membrane
0.37GO:0070062extracellular exosome
0.30GO:0031224intrinsic component of membrane
0.81EC:2.4.1 GO:0008378
sp|Q7Z7M9|GALT5_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 5
Search
GALNT5
0.52Polypeptide N-acetylgalactosaminyltransferase
0.72GO:0006486protein glycosylation
0.35GO:0006024glycosaminoglycan biosynthetic process
0.34GO:0044206UMP salvage
0.34GO:0009166nucleotide catabolic process
0.33GO:0009226nucleotide-sugar biosynthetic process
0.32GO:0055114oxidation-reduction process
0.68GO:0030246carbohydrate binding
0.64GO:0004653polypeptide N-acetylgalactosaminyltransferase activity
0.35GO:0046872metal ion binding
0.34GO:0004850uridine phosphorylase activity
0.32GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32GO:0004497monooxygenase activity
0.32GO:0048037cofactor binding
0.32GO:0046906tetrapyrrole binding
0.71GO:0000139Golgi membrane
0.30GO:0031224intrinsic component of membrane
0.64EC:2.4.1.41 GO:0004653
sp|Q7Z7N9|T179B_HUMAN
Transmembrane protein 179B
Search
TMEM179B
0.97Transmembrane protein 179B
0.45GO:0051090regulation of DNA binding transcription factor activity
0.41GO:0006352DNA-templated transcription, initiation
0.40GO:0043312neutrophil degranulation
0.42GO:0046982protein heterodimerization activity
0.36GO:0003899DNA-directed 5'-3' RNA polymerase activity
0.33GO:0003676nucleic acid binding
0.68GO:0016607nuclear speck
0.62GO:0005730nucleolus
0.46GO:0046695SLIK (SAGA-like) complex
0.45GO:0000124SAGA complex
0.45GO:0005669transcription factor TFIID complex
0.40GO:0101003ficolin-1-rich granule membrane
0.40GO:0035577azurophil granule membrane
0.34GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
0.36EC:2.7.7.6 GO:0003899
sp|Q86SE5|RALYL_HUMAN
RNA-binding Raly-like protein
Search
RALYL
0.97RALY RNA binding protein like
0.58GO:0003723RNA binding
0.51GO:0042802identical protein binding
0.43GO:0005634nucleus
0.30GO:0044425membrane part
sp|Q86SE8|NPM2_HUMAN
Nucleoplasmin-2
Search
NPM2
0.83Nucleophosmin/nucleoplasmin 2
0.81GO:0045836positive regulation of meiotic nuclear division
0.79GO:0001824blastocyst development
0.78GO:0009994oocyte differentiation
0.77GO:0007096regulation of exit from mitosis
0.76GO:0007338single fertilization
0.71GO:0006338chromatin remodeling
0.50GO:0008543fibroblast growth factor receptor signaling pathway
0.49GO:0045740positive regulation of DNA replication
0.48GO:0065009regulation of molecular function
0.47GO:0051260protein homooligomerization
0.69GO:0003682chromatin binding
0.50GO:0005104fibroblast growth factor receptor binding
0.48GO:0008083growth factor activity
0.45GO:0019899enzyme binding
0.42GO:0042393histone binding
0.36GO:0004222metalloendopeptidase activity
0.36GO:0003723RNA binding
0.35GO:0046872metal ion binding
0.34GO:0003677DNA binding
0.33GO:0008757S-adenosylmethionine-dependent methyltransferase activity
0.85GO:0000789cytoplasmic chromatin
0.69GO:0000790nuclear chromatin
0.43GO:0005576extracellular region
0.35GO:0005730nucleolus
0.34GO:0005680anaphase-promoting complex
0.34GO:0005654nucleoplasm
0.34GO:0005789endoplasmic reticulum membrane
0.33GO:0005856cytoskeleton
0.33GO:0005739mitochondrion
0.30GO:0031224intrinsic component of membrane
0.36EC:3.4.24 GO:0004222
sp|Q86SE9|PCGF5_HUMAN
Polycomb group RING finger protein 5
Search
PCGF5
0.97Polycomb group RING finger protein 5
0.72GO:0045944positive regulation of transcription by RNA polymerase II
0.53GO:0060819inactivation of X chromosome by genetic imprinting
0.51GO:0036353histone H2A-K119 monoubiquitination
0.39GO:0006351transcription, DNA-templated
0.40GO:0004842ubiquitin-protein transferase activity
0.38GO:0046872metal ion binding
0.38GO:0005515protein binding
0.38GO:0016874ligase activity
0.81GO:0031519PcG protein complex
0.74GO:0005813centrosome
0.70GO:0005730nucleolus
0.51GO:0000805X chromosome
0.41GO:0005654nucleoplasm
0.30GO:0016020membrane
0.38EC:6 GO:0016874
0.40KEGG:R03876 GO:0004842
sp|Q86SF2|GALT7_HUMAN
N-acetylgalactosaminyltransferase 7
Search
GALNT7
0.64Polypeptide N-acetylgalactosaminyltransferase
0.72GO:0006486protein glycosylation
0.33GO:0005975carbohydrate metabolic process
0.33GO:0043043peptide biosynthetic process
0.32GO:0010467gene expression
0.68GO:0030246carbohydrate binding
0.63GO:0016757transferase activity, transferring glycosyl groups
0.43GO:0140096catalytic activity, acting on a protein
0.34GO:0046872metal ion binding
0.33GO:0003735structural constituent of ribosome
0.71GO:0000139Golgi membrane
0.36GO:0070062extracellular exosome
0.33GO:0005840ribosome
0.30GO:0016021integral component of membrane
0.63EC:2.4 GO:0016757
sp|Q86SG2|ANR23_HUMAN
Ankyrin repeat domain-containing protein 23
Search
ANKRD23
0.96Ankyrin repeat domain-containing protein 1
0.54GO:0035914skeletal muscle cell differentiation
0.52GO:1901796regulation of signal transduction by p53 class mediator
0.51GO:2000291regulation of myoblast proliferation
0.50GO:0010832negative regulation of myotube differentiation
0.50GO:0045662negative regulation of myoblast differentiation
0.50GO:0043619regulation of transcription from RNA polymerase II promoter in response to oxidative stress
0.48GO:0042981regulation of apoptotic process
0.47GO:0045445myoblast differentiation
0.47GO:0001817regulation of cytokine production
0.46GO:1903507negative regulation of nucleic acid-templated transcription
0.84GO:0031432titin binding
0.55GO:0061629RNA polymerase II sequence-specific DNA binding transcription factor binding
0.51GO:0043422protein kinase B binding
0.46GO:0003712transcription cofactor activity
0.46GO:0003682chromatin binding
0.43GO:0070412R-SMAD binding
0.42GO:0001190transcriptional activator activity, RNA polymerase II transcription factor binding
0.42GO:0002039p53 binding
0.42GO:0042826histone deacetylase binding
0.36GO:0003677DNA binding
0.55GO:0005829cytosol
0.55GO:0031981nuclear lumen
0.55GO:0031674I band
0.53GO:0015629actin cytoskeleton
0.48GO:0000791euchromatin
0.39GO:0005667transcription factor complex
0.39GO:0014704intercalated disc
0.34GO:1905369endopeptidase complex
0.30GO:0016020membrane
0.33EC:4 GO:0016829
sp|Q86SG3|DAZ4_HUMAN
Deleted in azoospermia protein 4
Search
0.86Deleted in azoospermia protein 4
0.80GO:0007281germ cell development
0.56GO:0045727positive regulation of translation
0.30GO:0006446regulation of translational initiation
0.30GO:0048232male gamete generation
0.30GO:0007275multicellular organism development
0.30GO:0061013regulation of mRNA catabolic process
0.30GO:0045934negative regulation of nucleobase-containing compound metabolic process
0.30GO:0031330negative regulation of cellular catabolic process
0.30GO:0065008regulation of biological quality
0.30GO:0010605negative regulation of macromolecule metabolic process
0.76GO:0003729mRNA binding
0.62GO:0008494translation activator activity
0.30GO:0005515protein binding
0.30GO:0044464cell part
0.30GO:0032991macromolecular complex
0.30GO:0043226organelle
sp|Q86SG4|DPCA2_HUMAN
Putative Dresden prostate carcinoma protein 2
Search
0.30Putative Dresden prostate carcinoma protein 2
sp|Q86SG5|S1A7A_HUMAN
Protein S100-A7A
Search
0.47GO:0010820positive regulation of T cell chemotaxis
0.46GO:0090026positive regulation of monocyte chemotaxis
0.46GO:0071624positive regulation of granulocyte chemotaxis
0.46GO:0061844antimicrobial humoral immune response mediated by antimicrobial peptide
0.46GO:0051238sequestering of metal ion
0.45GO:0070374positive regulation of ERK1 and ERK2 cascade
0.44GO:0050829defense response to Gram-negative bacterium
0.44GO:0032496response to lipopolysaccharide
0.42GO:0000302response to reactive oxygen species
0.39GO:0043312neutrophil degranulation
0.70GO:0005509calcium ion binding
0.57GO:0046914transition metal ion binding
0.46GO:0050786RAGE receptor binding
0.43GO:0043621protein self-association
0.33GO:0005198structural molecule activity
0.46GO:0005615extracellular space
0.42GO:0031012extracellular matrix
0.41GO:0005783endoplasmic reticulum
0.40GO:0005829cytosol
0.40GO:0035578azurophil granule lumen
0.39GO:0005634nucleus
0.38GO:0005925focal adhesion
0.38GO:1903561extracellular vesicle
sp|Q86SG6|NEK8_HUMAN
Serine/threonine-protein kinase Nek8
Search
NEK8
0.95NIMA (Never in mitosis gene a)-related kinase 8
0.68GO:0035330regulation of hippo signaling
0.64GO:0007368determination of left/right symmetry
0.63GO:0006468protein phosphorylation
0.62GO:0007507heart development
0.61GO:0009887animal organ morphogenesis
0.64GO:0004672protein kinase activity
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.71GO:0097543ciliary inversin compartment
0.67GO:0097546ciliary base
0.30GO:0031224intrinsic component of membrane
sp|Q86SG7|LYG2_HUMAN
Lysozyme g-like protein 2
Search
0.86Goose-type lysozyme 1
0.76GO:0016998cell wall macromolecule catabolic process
0.73GO:0009253peptidoglycan catabolic process
0.59GO:0050830defense response to Gram-positive bacterium
0.37GO:0019835cytolysis
0.77GO:0003796lysozyme activity
0.50GO:0005576extracellular region
0.30GO:0044425membrane part
0.77EC:3.2.1.17 GO:0003796
sp|Q86SH2|ZAR1_HUMAN
Zygote arrest protein 1
Search
ZAR1
0.82Zygote arrest protein 1
0.55GO:0007275multicellular organism development
0.42GO:1905881positive regulation of oogenesis
0.41GO:0016441posttranscriptional gene silencing
0.40GO:0000003reproduction
0.40GO:0017148negative regulation of translation
0.43GO:1903231mRNA binding involved in posttranscriptional gene silencing
0.37GO:0005515protein binding
0.48GO:0005737cytoplasm
0.30GO:0044425membrane part
sp|Q86SH4|PRNT_HUMAN
Putative testis-specific prion protein
Search
PRNT
0.97Prion protein, testis-specific protein Prt
0.66GO:0005576extracellular region
sp|Q86SI9|CEI_HUMAN
Protein CEI
Search
sp|Q86SJ2|AMGO2_HUMAN
Amphoterin-induced protein 2
Search
AMIGO2
0.97Adhesion molecule with Ig like domain 2
0.73GO:0043066negative regulation of apoptotic process
0.64GO:0051965positive regulation of synapse assembly
0.56GO:0007413axonal fasciculation
0.55GO:0042552myelination
0.51GO:0007155cell adhesion
0.44GO:1901381positive regulation of potassium ion transmembrane transport
0.39GO:0065009regulation of molecular function
0.39GO:0007420brain development
0.35GO:0050772positive regulation of axonogenesis
0.35GO:0007409axonogenesis
0.45GO:0015459potassium channel regulator activity
0.36GO:0005515protein binding
0.47GO:0005887integral component of plasma membrane
0.45GO:0032809neuronal cell body membrane
0.43GO:0030425dendrite
0.42GO:0034705potassium channel complex
0.36GO:0005634nucleus
0.35GO:0043204perikaryon
0.34GO:0030424axon
sp|Q86SJ6|DSG4_HUMAN
Desmoglein-4
Search
DSG3
0.97LOW QUALITY PROTEIN: desmoglein-4
0.78GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.62GO:0001942hair follicle development
0.62GO:0030216keratinocyte differentiation
0.61GO:0030509BMP signaling pathway
0.40GO:0050821protein stabilization
0.38GO:0012501programmed cell death
0.70GO:0005509calcium ion binding
0.42GO:0045295gamma-catenin binding
0.63GO:0030057desmosome
0.55GO:0005886plasma membrane
0.39GO:0098562cytoplasmic side of membrane
0.38GO:0070062extracellular exosome
0.36GO:0005914spot adherens junction
0.34GO:0005829cytosol
0.30GO:0016021integral component of membrane
sp|Q86SK9|SCD5_HUMAN
Stearoyl-CoA desaturase 5
Search
SCD5
0.58Stearoyl-CoA desaturase
0.70GO:0006633fatty acid biosynthetic process
0.56GO:0033559unsaturated fatty acid metabolic process
0.53GO:0055114oxidation-reduction process
0.36GO:0046949fatty-acyl-CoA biosynthetic process
0.34GO:0001510RNA methylation
0.34GO:0006396RNA processing
0.80GO:0016717oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
0.35GO:0005506iron ion binding
0.34GO:0008173RNA methyltransferase activity
0.49GO:0005789endoplasmic reticulum membrane
0.36GO:0005730nucleolus
0.30GO:0016021integral component of membrane
0.80EC:1.14.19 GO:0016717
sp|Q86SM5|MRGRG_HUMAN
Mas-related G-protein coupled receptor member G
Search
MRGPRG
0.92MAS related GPR family member G
0.71GO:0007186G-protein coupled receptor signaling pathway
0.41GO:1902349response to chloroquine
0.37GO:0007166cell surface receptor signaling pathway
0.72GO:0004930G-protein coupled receptor activity
0.41GO:0005887integral component of plasma membrane
sp|Q86SM8|MRGRE_HUMAN
Mas-related G-protein coupled receptor member E
Search
0.95Mas-related G-protein coupled receptor member E
0.71GO:0007186G-protein coupled receptor signaling pathway
0.59GO:1903955positive regulation of protein targeting to mitochondrion
0.37GO:0002279mast cell activation involved in immune response
0.37GO:0002448mast cell mediated immunity
0.37GO:0043299leukocyte degranulation
0.37GO:0032418lysosome localization
0.36GO:0051656establishment of organelle localization
0.35GO:0032467positive regulation of cytokinesis
0.35GO:0046907intracellular transport
0.72GO:0004930G-protein coupled receptor activity
0.35GO:0042923neuropeptide binding
0.43GO:0005887integral component of plasma membrane
0.37GO:0042629mast cell granule
sp|Q86SP6|GP149_HUMAN
Probable G-protein coupled receptor 149
Search
GPR149
0.90G protein-coupled receptor 149
0.69GO:0060280negative regulation of ovulation
0.67GO:0001547antral ovarian follicle growth
0.66GO:0048162multi-layer follicle stage
0.51GO:0007186G-protein coupled receptor signaling pathway
0.48GO:0007268chemical synaptic transmission
0.52GO:0042923neuropeptide binding
0.52GO:0004930G-protein coupled receptor activity
0.48GO:0043005neuron projection
0.44GO:0005887integral component of plasma membrane
sp|Q86SQ0|PHLB2_HUMAN
Pleckstrin homology-like domain family B member 2
Search
PHLDB2
0.96Pleckstrin homology like domain family B member 2
0.87GO:1903690negative regulation of wound healing, spreading of epidermal cells
0.87GO:1904259regulation of basement membrane assembly involved in embryonic body morphogenesis
0.86GO:1901203positive regulation of extracellular matrix assembly
0.86GO:0051497negative regulation of stress fiber assembly
0.86GO:0051895negative regulation of focal adhesion assembly
0.85GO:0040019positive regulation of embryonic development
0.85GO:0010470regulation of gastrulation
0.84GO:0010717regulation of epithelial to mesenchymal transition
0.80GO:0070507regulation of microtubule cytoskeleton organization
0.75GO:0000226microtubule cytoskeleton organization
0.81GO:0045296cadherin binding
0.86GO:0045180basal cortex
0.81GO:0005925focal adhesion
0.80GO:0031252cell leading edge
0.77GO:0045111intermediate filament cytoskeleton
0.67GO:0005829cytosol
0.55GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q86SQ3|AGRE4_HUMAN
Putative adhesion G protein-coupled receptor E4P
Search
0.84LOW QUALITY PROTEIN: EGF-like module-containing mucin-like hormone receptor-like 3
0.71GO:0007186G-protein coupled receptor signaling pathway
0.70GO:0007166cell surface receptor signaling pathway
0.72GO:0004930G-protein coupled receptor activity
0.60GO:0005509calcium ion binding
0.30GO:0044425membrane part
sp|Q86SQ4|AGRG6_HUMAN
Adhesion G-protein coupled receptor G6
Search
ADGRG6
0.94Adhesion G-protein coupled receptor G6
0.73GO:0060347heart trabecula formation
0.72GO:0014037Schwann cell differentiation
0.71GO:0032292peripheral nervous system axon ensheathment
0.71GO:0007166cell surface receptor signaling pathway
0.71GO:0007186G-protein coupled receptor signaling pathway
0.70GO:0042552myelination
0.70GO:0019933cAMP-mediated signaling
0.69GO:0021782glial cell development
0.63GO:0007005mitochondrion organization
0.37GO:0060879semicircular canal fusion
0.72GO:0004930G-protein coupled receptor activity
0.71GO:0043236laminin binding
0.42GO:0005518collagen binding
0.49GO:0005886plasma membrane
0.41GO:0005622intracellular
0.36GO:0009986cell surface
0.30GO:0016021integral component of membrane
sp|Q86SQ6|AGRA1_HUMAN
Adhesion G protein-coupled receptor A1
Search
ADGRA1
0.97Adhesion G protein-coupled receptor A1
0.71GO:0007186G-protein coupled receptor signaling pathway
0.70GO:0007166cell surface receptor signaling pathway
0.36GO:0097475motor neuron migration
0.36GO:2000095regulation of Wnt signaling pathway, planar cell polarity pathway
0.35GO:0060027convergent extension involved in gastrulation
0.35GO:0003401axis elongation
0.35GO:0198738cell-cell signaling by wnt
0.72GO:0004930G-protein coupled receptor activity
0.33GO:0005515protein binding
0.49GO:0009897external side of plasma membrane
0.30GO:0016021integral component of membrane
sp|Q86SQ7|SDCG8_HUMAN
Serologically defined colon cancer antigen 8
Search
SDCCAG8
0.97Serologically defined colon cancer antigen 8
0.82GO:0007098centrosome cycle
0.60GO:0001764neuron migration
0.60GO:0035148tube formation
0.59GO:0030010establishment of cell polarity
0.41GO:0043009chordate embryonic development
0.38GO:0097711ciliary basal body-plasma membrane docking
0.37GO:0000086G2/M transition of mitotic cell cycle
0.36GO:0010389regulation of G2/M transition of mitotic cell cycle
0.35GO:0005515protein binding
0.77GO:0005813centrosome
0.61GO:0005814centriole
0.57GO:0005911cell-cell junction
0.35GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q86SQ9|DHDDS_HUMAN
Dehydrodolichyl diphosphate synthase complex subunit DHDDS
Search
DHDDS
0.73Dehydrodolichyl diphosphate synthase complex subunit DHDDS
0.73GO:0043413macromolecule glycosylation
0.73GO:0009101glycoprotein biosynthetic process
0.59GO:0006464cellular protein modification process
0.49GO:0016094polyprenol biosynthetic process
0.46GO:0050908detection of light stimulus involved in visual perception
0.45GO:0042462eye photoreceptor cell development
0.36GO:0006489dolichyl diphosphate biosynthetic process
0.69GO:0016765transferase activity, transferring alkyl or aryl (other than methyl) groups
0.35GO:0031492nucleosomal DNA binding
0.33GO:0005515protein binding
0.35GO:0005789endoplasmic reticulum membrane
0.34GO:0000785chromatin
0.33GO:0005634nucleus
0.69EC:2.5 EC:2.5.1 GO:0016765
sp|Q86SR1|GLT10_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 10
Search
GALNT10
0.65Polypeptide N-acetylgalactosaminyltransferase
0.73GO:0043413macromolecule glycosylation
0.73GO:0009101glycoprotein biosynthetic process
0.59GO:0036211protein modification process
0.55GO:0044267cellular protein metabolic process
0.69GO:0030246carbohydrate binding
0.64GO:0016757transferase activity, transferring glycosyl groups
0.45GO:0140096catalytic activity, acting on a protein
0.34GO:0046872metal ion binding
0.73GO:0000139Golgi membrane
0.30GO:0031224intrinsic component of membrane
0.64EC:2.4 GO:0016757
sp|Q86SS6|SYT9_HUMAN
Synaptotagmin-9
Search
SYT9
0.97Synaptotagmin IXb
0.85GO:0017158regulation of calcium ion-dependent exocytosis
0.84GO:0050796regulation of insulin secretion
0.50GO:0048791calcium ion-regulated exocytosis of neurotransmitter
0.48GO:0006906vesicle fusion
0.39GO:1903307positive regulation of regulated secretory pathway
0.36GO:0005513detection of calcium ion
0.56GO:0001786phosphatidylserine binding
0.55GO:0000149SNARE binding
0.55GO:0005546phosphatidylinositol-4,5-bisphosphate binding
0.49GO:0042802identical protein binding
0.48GO:0005544calcium-dependent phospholipid binding
0.47GO:0030276clathrin binding
0.44GO:0005509calcium ion binding
0.57GO:0031045dense core granule
0.47GO:0098793presynapse
0.39GO:0005886plasma membrane
0.39GO:0099501exocytic vesicle membrane
0.39GO:0030667secretory granule membrane
0.37GO:0030054cell junction
0.35GO:0030665clathrin-coated vesicle membrane
0.30GO:0016021integral component of membrane
sp|Q86SU0|ILDR1_HUMAN
Immunoglobulin-like domain-containing receptor 1
Search
ILDR1
0.97Immunoglobulin like domain containing receptor 1
0.62GO:0090277positive regulation of peptide hormone secretion
0.61GO:1990830cellular response to leukemia inhibitory factor
0.59GO:0051260protein homooligomerization
0.54GO:0006898receptor-mediated endocytosis
0.44GO:0048922posterior lateral line neuromast deposition
0.44GO:1904274tricellular tight junction assembly
0.44GO:0061833protein localization to tricellular tight junction
0.43GO:0060872semicircular canal development
0.43GO:0060856establishment of blood-brain barrier
0.42GO:0001889liver development
0.67GO:0070506high-density lipoprotein particle receptor activity
0.56GO:0042802identical protein binding
0.33GO:0017129triglyceride binding
0.33GO:0030169low-density lipoprotein particle binding
0.33GO:0005504fatty acid binding
0.32GO:0046983protein dimerization activity
0.66GO:0061689tricellular tight junction
0.48GO:0043234protein complex
0.46GO:0005886plasma membrane
0.38GO:0005829cytosol
0.35GO:0034362low-density lipoprotein particle
0.35GO:0042627chylomicron
0.35GO:0034361very-low-density lipoprotein particle
0.34GO:0070062extracellular exosome
0.30GO:0016021integral component of membrane
sp|Q86SX3|CN080_HUMAN
Uncharacterized protein C14orf80
Search
sp|Q86SX6|GLRX5_HUMAN
Glutaredoxin-related protein 5, mitochondrial
Search
GLRX5
0.76Glutaredoxin-related protein 5, mitochondrial
0.69GO:0045454cell redox homeostasis
0.61GO:0022900electron transport chain
0.47GO:0030097hemopoiesis
0.44GO:0009249protein lipoylation
0.37GO:0016226iron-sulfur cluster assembly
0.35GO:0044281small molecule metabolic process
0.72GO:0015035protein disulfide oxidoreductase activity
0.66GO:00515372 iron, 2 sulfur cluster binding
0.62GO:0009055electron transfer activity
0.51GO:0046872metal ion binding
0.37GO:0005515protein binding
0.45GO:0043025neuronal cell body
0.45GO:0030425dendrite
0.43GO:0005759mitochondrial matrix
0.39GO:0005634nucleus
sp|Q86SY8|KTAS1_HUMAN
Putative uncharacterized protein KTN1-AS1
Search
sp|Q86SZ2|TPC6B_HUMAN
Trafficking protein particle complex subunit 6B
Search
TRAPPC6B
0.89Trafficking protein particle complex subunit 6B
0.76GO:0048193Golgi vesicle transport
0.75GO:0043087regulation of GTPase activity
0.45GO:0046907intracellular transport
0.36GO:0006900vesicle budding from membrane
0.35GO:0006903vesicle targeting
0.34GO:0006461protein complex assembly
0.33GO:0034613cellular protein localization
0.33GO:0015031protein transport
0.35GO:0017112Rab guanyl-nucleotide exchange factor activity
0.49GO:0005801cis-Golgi network
0.49GO:0030008TRAPP complex
0.48GO:0005802trans-Golgi network
0.36GO:0005783endoplasmic reticulum
0.35GO:0000139Golgi membrane
0.34GO:0030127COPII vesicle coat
0.34GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q86T03|TM55B_HUMAN
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
Search
TMEM55B
0.97Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A
0.81GO:0046856phosphatidylinositol dephosphorylation
0.86GO:0034597phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
0.56GO:0031902late endosome membrane
0.55GO:0005765lysosomal membrane
0.34GO:0005654nucleoplasm
0.30GO:0031224intrinsic component of membrane
0.86EC:3.1.3.66 GO:0034597
sp|Q86T13|CLC14_HUMAN
C-type lectin domain family 14 member A
Search
CLEC14A
0.97C-type lectin domain containing 14A
0.39GO:0002042cell migration involved in sprouting angiogenesis
0.76GO:1990430extracellular matrix protein binding
0.57GO:0030246carbohydrate binding
0.68GO:0009897external side of plasma membrane
0.43GO:0070062extracellular exosome
0.43GO:0031012extracellular matrix
0.30GO:0031224intrinsic component of membrane
sp|Q86T20|CF001_HUMAN
Uncharacterized protein C6orf1
Search
SMIM29
0.96Small integral membrane protein 29
0.66GO:0005576extracellular region
sp|Q86T23|CROL1_HUMAN
Putative ciliary rootlet coiled-coil protein-like 1 protein
Search
0.12Putative ciliary rootlet coiled-coil protein-like 1 protein
0.83GO:0007098centrosome cycle
0.72GO:1903566positive regulation of protein localization to cilium
0.71GO:0032053ciliary basal body organization
0.69GO:0045724positive regulation of cilium assembly
0.68GO:0010669epithelial structure maintenance
0.67GO:0045494photoreceptor cell maintenance
0.61GO:0051656establishment of organelle localization
0.58GO:0033365protein localization to organelle
0.67GO:0019894kinesin binding
0.59GO:0003779actin binding
0.51GO:0005198structural molecule activity
0.86GO:0035253ciliary rootlet
0.67GO:0001917photoreceptor inner segment
0.65GO:0005814centriole
0.63GO:0005813centrosome
0.60GO:0015629actin cytoskeleton
0.56GO:0005829cytosol
0.47GO:0005886plasma membrane
0.44GO:0070062extracellular exosome
sp|Q86T24|KAISO_HUMAN
Transcriptional regulator Kaiso
Search
ZBTB33
0.97Transcriptional regulator Kaiso
0.55GO:0045892negative regulation of transcription, DNA-templated
0.38GO:0016055Wnt signaling pathway
0.37GO:0006357regulation of transcription by RNA polymerase II
0.36GO:0006974cellular response to DNA damage stimulus
0.35GO:0006351transcription, DNA-templated
0.35GO:0042074cell migration involved in gastrulation
0.34GO:0030178negative regulation of Wnt signaling pathway
0.34GO:0035556intracellular signal transduction
0.32GO:0060027convergent extension involved in gastrulation
0.32GO:0009953dorsal/ventral pattern formation
0.66GO:0008327methyl-CpG binding
0.41GO:0010428methyl-CpNpG binding
0.39GO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38GO:0044212transcription regulatory region DNA binding
0.38GO:0019901protein kinase binding
0.37GO:0042803protein homodimerization activity
0.37GO:1990837sequence-specific double-stranded DNA binding
0.34GO:0046872metal ion binding
0.34GO:0008013beta-catenin binding
0.55GO:0005730nucleolus
0.54GO:0005654nucleoplasm
0.53GO:0005829cytosol
0.45GO:0005886plasma membrane
0.33GO:0005694chromosome
sp|Q86T26|TM11B_HUMAN
Transmembrane protease serine 11B
Search
0.91Transmembrane protease serine
0.59GO:0006508proteolysis
0.34GO:0007596blood coagulation
0.34GO:0006898receptor-mediated endocytosis
0.33GO:0043010camera-type eye development
0.33GO:0007049cell cycle
0.67GO:0004252serine-type endopeptidase activity
0.34GO:0005044scavenger receptor activity
0.33GO:0005509calcium ion binding
0.58GO:0005887integral component of plasma membrane
0.58GO:0005576extracellular region
0.44GO:0043204perikaryon
0.42GO:0030425dendrite
0.37GO:0031982vesicle
0.33GO:0005789endoplasmic reticulum membrane
0.67EC:3.4.21 GO:0004252
sp|Q86T29|ZN605_HUMAN
Zinc finger protein 605
Search
0.68RB associated KRAB zinc finger
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.48GO:0097659nucleic acid-templated transcription
0.45GO:0010467gene expression
0.45GO:0034645cellular macromolecule biosynthetic process
0.54GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.50GO:0003700DNA binding transcription factor activity
0.55GO:0005634nucleus
0.46GO:0043233organelle lumen
0.42GO:0044446intracellular organelle part
sp|Q86T65|DAAM2_HUMAN
Disheveled-associated activator of morphogenesis 2
Search
DAAM2
0.94Dishevelled associated activator of morphogenesis 2
0.73GO:0030036actin cytoskeleton organization
0.53GO:0048715negative regulation of oligodendrocyte differentiation
0.52GO:0021516dorsal spinal cord development
0.52GO:2000050regulation of non-canonical Wnt signaling pathway
0.51GO:0090263positive regulation of canonical Wnt signaling pathway
0.50GO:0007368determination of left/right symmetry
0.36GO:0030838positive regulation of actin filament polymerization
0.36GO:0097435supramolecular fiber organization
0.35GO:0060071Wnt signaling pathway, planar cell polarity pathway
0.77GO:0017048Rho GTPase binding
0.73GO:0003779actin binding
0.46GO:0042802identical protein binding
0.36GO:0008017microtubule binding
0.32GO:0003676nucleic acid binding
0.50GO:0097517contractile actin filament bundle
0.50GO:0042641actomyosin
0.49GO:0036064ciliary basal body
0.48GO:0031514motile cilium
0.44GO:0005829cytosol
0.39GO:0005886plasma membrane
0.37GO:0005884actin filament
0.36GO:0070062extracellular exosome
sp|Q86T75|NBPFB_HUMAN
Neuroblastoma breakpoint family member 11
Search
0.10Neuroblastoma breakpoint family member 11
0.48GO:0005737cytoplasm
0.30GO:0044425membrane part
sp|Q86T82|UBP37_HUMAN
Ubiquitin carboxyl-terminal hydrolase 37
Search
USP37
0.96Ubiquitin carboxyl-terminal hydrolase 37
0.75GO:0016579protein deubiquitination
0.72GO:0006511ubiquitin-dependent protein catabolic process
0.58GO:0000082G1/S transition of mitotic cell cycle
0.53GO:0006275regulation of DNA replication
0.39GO:0051301cell division
0.33GO:0021551central nervous system morphogenesis
0.33GO:1904888cranial skeletal system development
0.76GO:0036459thiol-dependent ubiquitinyl hydrolase activity
0.53GO:0019901protein kinase binding
0.53GO:0004197cysteine-type endopeptidase activity
0.45GO:0005634nucleus
0.34GO:0031974membrane-enclosed lumen
0.33GO:0044446intracellular organelle part
0.76EC:3.4.19.12 GO:0036459
sp|Q86T90|K1328_HUMAN
Protein hinderin
Search
0.37GO:0016310phosphorylation
0.54GO:0005515protein binding
0.38GO:0016301kinase activity
0.30GO:0044425membrane part
sp|Q86T96|RN180_HUMAN
E3 ubiquitin-protein ligase RNF180
Search
RNF180
0.52E3 ubiquitin-protein ligase
0.82GO:0000209protein polyubiquitination
0.52GO:0042415norepinephrine metabolic process
0.52GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.51GO:0042428serotonin metabolic process
0.49GO:0030534adult behavior
0.40GO:0031398positive regulation of protein ubiquitination
0.37GO:0050790regulation of catalytic activity
0.32GO:0006783heme biosynthetic process
0.32GO:0043043peptide biosynthetic process
0.31GO:0010467gene expression
0.76GO:0061630ubiquitin protein ligase activity
0.52GO:0031624ubiquitin conjugating enzyme binding
0.50GO:0016874ligase activity
0.36GO:0046872metal ion binding
0.32GO:0004325ferrochelatase activity
0.32GO:0003735structural constituent of ribosome
0.41GO:0005789endoplasmic reticulum membrane
0.39GO:0005635nuclear envelope
0.32GO:0005840ribosome
0.30GO:0016021integral component of membrane
0.50EC:6 GO:0016874
0.32KEGG:R00310 GO:0004325
sp|Q86TA1|MOB3B_HUMAN
MOB kinase activator 3B
Search
MOB3B
0.94MOB kinase activator 3B
0.55GO:0016310phosphorylation
0.34GO:0006464cellular protein modification process
0.57GO:0016301kinase activity
0.35GO:0046872metal ion binding
0.34GO:0016773phosphotransferase activity, alcohol group as acceptor
0.34GO:0140096catalytic activity, acting on a protein
0.34GO:0005515protein binding
0.33GO:0030554adenyl nucleotide binding
0.33GO:0097367carbohydrate derivative binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0005622intracellular
0.30GO:0031224intrinsic component of membrane
0.34EC:2.7.1 GO:0016773
sp|Q86TA4|YB049_HUMAN
Putative uncharacterized protein FLJ44553
Search
sp|Q86TB3|ALPK2_HUMAN
Alpha-protein kinase 2
Search
ALPK2
0.88Alpha-protein kinase 2
0.62GO:0006468protein phosphorylation
0.37GO:0007507heart development
0.36GO:0055002striated muscle cell development
0.36GO:0014706striated muscle tissue development
0.35GO:1901642nucleoside transmembrane transport
0.69GO:0004674protein serine/threonine kinase activity
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0005337nucleoside transmembrane transporter activity
0.37GO:0005737cytoplasm
0.34GO:0005634nucleus
0.30GO:0016020membrane
0.69EC:2.7.11 GO:0004674
sp|Q86TB9|PATL1_HUMAN
Protein PAT1 homolog 1
Search
PATL1
0.97PAT1 homolog 1, processing body mRNA decay factor
0.83GO:0033962cytoplasmic mRNA processing body assembly
0.79GO:0000290deadenylation-dependent decapping of nuclear-transcribed mRNA
0.44GO:0006869lipid transport
0.40GO:0043928exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.39GO:0017148negative regulation of translation
0.37GO:0010607negative regulation of cytoplasmic mRNA processing body assembly
0.36GO:0050911detection of chemical stimulus involved in sensory perception of smell
0.35GO:0007186G-protein coupled receptor signaling pathway
0.31GO:0006468protein phosphorylation
0.82GO:0034046poly(G) binding
0.78GO:0008266poly(U) RNA binding
0.41GO:0002151G-quadruplex RNA binding
0.41GO:0030371translation repressor activity
0.40GO:0016853isomerase activity
0.36GO:0004984olfactory receptor activity
0.36GO:0005515protein binding
0.36GO:0004930G-protein coupled receptor activity
0.31GO:0004672protein kinase activity
0.31GO:0030554adenyl nucleotide binding
0.77GO:0000932P-body
0.75GO:0030014CCR4-NOT complex
0.49GO:0016605PML body
0.48GO:0016607nuclear speck
0.37GO:0005829cytosol
0.34GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
0.40EC:5 GO:0016853
sp|Q86TC9|MYPN_HUMAN
Myopalladin
Search
MYPN
0.90Myopalladin
0.79GO:0055002striated muscle cell development
0.75GO:0031032actomyosin structure organization
0.75GO:0010927cellular component assembly involved in morphogenesis
0.68GO:0097435supramolecular fiber organization
0.66GO:0070925organelle assembly
0.63GO:0055006cardiac cell development
0.63GO:0055007cardiac muscle cell differentiation
0.59GO:0030334regulation of cell migration
0.57GO:0051493regulation of cytoskeleton organization
0.47GO:0016477cell migration
0.83GO:0051371muscle alpha-actinin binding
0.73GO:0017124SH3 domain binding
0.58GO:0051015actin filament binding
0.33GO:0004984olfactory receptor activity
0.33GO:0046983protein dimerization activity
0.33GO:0004930G-protein coupled receptor activity
0.80GO:0030018Z disc
0.39GO:0005634nucleus
0.38GO:0005884actin filament
0.36GO:0005829cytosol
0.35GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q86TD4|SRCA_HUMAN
Sarcalumenin
Search
SRL
0.79Sarcalumenin
0.54GO:0014873response to muscle activity involved in regulation of muscle adaptation
0.52GO:0002115store-operated calcium entry
0.66GO:0032550purine ribonucleoside binding
0.65GO:0019001guanyl nucleotide binding
0.54GO:0032553ribonucleotide binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.42GO:0033018sarcoplasmic reticulum lumen
0.30GO:0016021integral component of membrane
sp|Q86TE4|LUZP2_HUMAN
Leucine zipper protein 2
Search
LUZP2
0.97Leucine zipper protein 2
0.36GO:0006606protein import into nucleus
0.60GO:0005576extracellular region
0.30GO:0016021integral component of membrane
sp|Q86TG1|T150A_HUMAN
Transmembrane protein 150A
Search
TMEM150A
0.90DNA damage-regulated autophagy modulator protein 2
0.57GO:0072659protein localization to plasma membrane
0.53GO:0046854phosphatidylinositol phosphorylation
0.35GO:0009056catabolic process
0.33GO:0005515protein binding
0.49GO:0005887integral component of plasma membrane
0.48GO:0005764lysosome
sp|Q86TG7|PEG10_HUMAN
Retrotransposon-derived protein PEG10
Search
PEG10
0.65LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10
0.53GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway
0.50GO:0006915apoptotic process
0.47GO:0030154cell differentiation
0.43GO:0001890placenta development
0.63GO:0008270zinc ion binding
0.51GO:0003676nucleic acid binding
0.41GO:0005515protein binding
0.59GO:0005829cytosol
0.54GO:0005634nucleus
sp|Q86TH1|ATL2_HUMAN
ADAMTS-like protein 2
Search
ADAMTSL2
0.97ADAMTS like 2
0.64GO:0060481lobar bronchus epithelium development
0.60GO:0006508proteolysis
0.60GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway
0.57GO:0030198extracellular matrix organization
0.65GO:0050436microfibril binding
0.60GO:0008233peptidase activity
0.34GO:0005515protein binding
0.32GO:0046872metal ion binding
0.54GO:0005578proteinaceous extracellular matrix
0.30GO:0016021integral component of membrane
0.60EC:3.4 GO:0008233
sp|Q86TI0|TBCD1_HUMAN
TBC1 domain family member 1
Search
TBC1D1
0.87TBC1 domain family member 1 isoform 1
0.80GO:0031338regulation of vesicle fusion
0.79GO:0090630activation of GTPase activity
0.65GO:0006886intracellular protein transport
0.58GO:0032880regulation of protein localization
0.55GO:1902017regulation of cilium assembly
0.47GO:0061024membrane organization
0.76GO:0017137Rab GTPase binding
0.72GO:0005096GTPase activator activity
0.64GO:0012505endomembrane system
0.49GO:0005634nucleus
0.47GO:0005829cytosol
sp|Q86TI2|DPP9_HUMAN
Dipeptidyl peptidase 9
Search
DPP9
0.96Dipeptidyl peptidase 9
0.61GO:0006508proteolysis
0.66GO:0008236serine-type peptidase activity
0.49GO:0042802identical protein binding
0.35GO:0004177aminopeptidase activity
0.32GO:0008234cysteine-type peptidase activity
0.47GO:0005829cytosol
0.33GO:0005634nucleus
0.35EC:3.4.11 GO:0004177
sp|Q86TI4|WDR86_HUMAN
WD repeat-containing protein 86
Search
WDR86
0.97WD repeat-containing protein 86
sp|Q86TJ2|TAD2B_HUMAN
Transcriptional adapter 2-beta
Search
TADA2B
0.79Transcriptional adapter
0.74GO:0035065regulation of histone acetylation
0.63GO:0006357regulation of transcription by RNA polymerase II
0.50GO:0006351transcription, DNA-templated
0.50GO:2000758positive regulation of peptidyl-lysine acetylation
0.49GO:0031058positive regulation of histone modification
0.47GO:0016573histone acetylation
0.47GO:0006338chromatin remodeling
0.35GO:0016579protein deubiquitination
0.70GO:0003713transcription coactivator activity
0.55GO:0008270zinc ion binding
0.55GO:0003677DNA binding
0.47GO:0004402histone acetyltransferase activity
0.46GO:0003682chromatin binding
0.41GO:0003700DNA binding transcription factor activity
0.35GO:0036459thiol-dependent ubiquitinyl hydrolase activity
0.34GO:0005515protein binding
0.57GO:0005634nucleus
0.54GO:0031248protein acetyltransferase complex
0.49GO:0031974membrane-enclosed lumen
0.45GO:0043234protein complex
0.44GO:0044446intracellular organelle part
0.30GO:0031224intrinsic component of membrane
0.47EC:2.3.1.48 GO:0004402
sp|Q86TJ5|ZN554_HUMAN
Zinc finger protein 554
Search
ZNF554
0.82Zinc finger protein 554
0.53GO:1903506regulation of nucleic acid-templated transcription
0.53GO:2000112regulation of cellular macromolecule biosynthetic process
0.53GO:0010468regulation of gene expression
0.41GO:0006351transcription, DNA-templated
0.36GO:0042035regulation of cytokine biosynthetic process
0.35GO:1902680positive regulation of RNA biosynthetic process
0.34GO:1902679negative regulation of RNA biosynthetic process
0.51GO:0003676nucleic acid binding
0.50GO:0046872metal ion binding
0.42GO:0003700DNA binding transcription factor activity
0.35GO:0003682chromatin binding
0.56GO:0005730nucleolus
0.35GO:0097197tetraspanin-enriched microdomain
0.35GO:0001772immunological synapse
0.30GO:0031224intrinsic component of membrane
sp|Q86TL0|ATG4D_HUMAN
Cysteine protease ATG4D
Search
ATG4D
0.59Cysteine protease
0.77GO:0006914autophagy
0.65GO:0015031protein transport
0.60GO:0006508proteolysis
0.53GO:0051697protein delipidation
0.52GO:0006501C-terminal protein lipidation
0.51GO:0007033vacuole organization
0.50GO:0061726mitochondrion disassembly
0.47GO:0070925organelle assembly
0.46GO:0090150establishment of protein localization to membrane
0.44GO:0046907intracellular transport
0.72GO:0008234cysteine-type peptidase activity
0.47GO:0004175endopeptidase activity
0.48GO:0005737cytoplasm
0.38GO:0005576extracellular region
0.37GO:0031974membrane-enclosed lumen
0.35GO:0044446intracellular organelle part
0.35GO:0043231intracellular membrane-bounded organelle
0.72EC:3.4 GO:0008234
sp|Q86TL2|STIMA_HUMAN
Store-operated calcium entry regulator STIMATE
Search
TMEM110
0.90Transmembrane protein 110
0.44GO:0035988chondrocyte proliferation
0.43GO:0002062chondrocyte differentiation
0.43GO:0042246tissue regeneration
0.38GO:0005634nucleus
0.30GO:0044425membrane part
sp|Q86TM3|DDX53_HUMAN
Probable ATP-dependent RNA helicase DDX53
Search
DDX43
0.97DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
0.51GO:0010501RNA secondary structure unwinding
0.35GO:0071805potassium ion transmembrane transport
0.34GO:0031047gene silencing by RNA
0.33GO:0006955immune response
0.33GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
0.33GO:0006396RNA processing
0.66GO:0004386helicase activity
0.57GO:0003723RNA binding
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.48GO:0008186RNA-dependent ATPase activity
0.43GO:0140098catalytic activity, acting on RNA
0.35GO:0005249voltage-gated potassium channel activity
0.33GO:0016893endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
0.32GO:0016740transferase activity
0.47GO:0005730nucleolus
0.38GO:0005737cytoplasm
0.35GO:0008076voltage-gated potassium channel complex
0.33EC:3.1.30 GO:0016893
sp|Q86TM6|SYVN1_HUMAN
E3 ubiquitin-protein ligase synoviolin
Search
SYVN1
0.91Synovial apoptosis inhibitor 1, synoviolin
0.81GO:0030433ubiquitin-dependent ERAD pathway
0.71GO:0016567protein ubiquitination
0.63GO:1902236negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.61GO:1903513endoplasmic reticulum to cytosol transport
0.61GO:0018279protein N-linked glycosylation via asparagine
0.61GO:0032527protein exit from endoplasmic reticulum
0.57GO:0050821protein stabilization
0.50GO:0030968endoplasmic reticulum unfolded protein response
0.38GO:0001701in utero embryonic development
0.37GO:1904380endoplasmic reticulum mannose trimming
0.75GO:0061630ubiquitin protein ligase activity
0.64GO:1990381ubiquitin-specific protease binding
0.61GO:0051117ATPase binding
0.56GO:0051087chaperone binding
0.54GO:0051082unfolded protein binding
0.48GO:0016874ligase activity
0.36GO:0046872metal ion binding
0.84GO:0000836Hrd1p ubiquitin ligase complex
0.64GO:0036513Derlin-1 retrotranslocation complex
0.62GO:0005790smooth endoplasmic reticulum
0.52GO:0044322endoplasmic reticulum quality control compartment
0.52GO:0005654nucleoplasm
0.36GO:0030176integral component of endoplasmic reticulum membrane
0.48EC:6 GO:0016874
sp|Q86TN4|TRPT1_HUMAN
tRNA 2'-phosphotransferase 1
Search
TRPT1
0.95LOW QUALITY PROTEIN: tRNA 2'-phosphotransferase 1
0.81GO:0006388tRNA splicing, via endonucleolytic cleavage and ligation
0.52GO:0045859regulation of protein kinase activity
0.33GO:0006470protein dephosphorylation
0.61GO:0000215tRNA 2'-phosphotransferase activity
0.33GO:0004722protein serine/threonine phosphatase activity
0.32GO:0003676nucleic acid binding
0.32GO:0016746transferase activity, transferring acyl groups
0.32GO:0046872metal ion binding
0.33GO:0005634nucleus
0.32GO:0005737cytoplasm
0.30GO:0016020membrane
0.61EC:2.7.1.160 GO:0000215
sp|Q86TP1|PRUNE_HUMAN
Protein prune homolog
Search
PRUNE1
0.75Prune exopolyphosphatase
0.63GO:0031113regulation of microtubule polymerization
0.59GO:0050767regulation of neurogenesis
0.53GO:0016311dephosphorylation
0.33GO:0043412macromolecule modification
0.33GO:0044267cellular protein metabolic process
0.32GO:0016310phosphorylation
0.32GO:0006508proteolysis
0.31GO:0016070RNA metabolic process
0.58GO:0016462pyrophosphatase activity
0.56GO:0015631tubulin binding
0.53GO:0016791phosphatase activity
0.36GO:0046872metal ion binding
0.33GO:0004672protein kinase activity
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0009982pseudouridine synthase activity
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0003723RNA binding
0.53GO:0005829cytosol
0.41GO:0005925focal adhesion
0.37GO:0005634nucleus
0.32GO:0043234protein complex
0.32GO:0044446intracellular organelle part
0.30GO:0016020membrane
0.58EC:3.6.1 GO:0016462
sp|Q86TS7|U730_HUMAN
Putative UPF0730 protein encoded by LINC00643
Search
0.77GO:0006887exocytosis
sp|Q86TS9|RM52_HUMAN
39S ribosomal protein L52, mitochondrial
Search
MRPL52
0.95Mitochondrial ribosomal protein L52
0.80GO:0032543mitochondrial translation
0.36GO:0006415translational termination
0.36GO:0006414translational elongation
0.34GO:0006508proteolysis
0.63GO:0003735structural constituent of ribosome
0.35GO:0004222metalloendopeptidase activity
0.34GO:0008270zinc ion binding
0.81GO:0005762mitochondrial large ribosomal subunit
0.36GO:0031966mitochondrial membrane
0.36GO:0019866organelle inner membrane
0.36GO:0031012extracellular matrix
0.30GO:0016021integral component of membrane
0.35EC:3.4.24 GO:0004222
sp|Q86TU6|CN070_HUMAN
Putative uncharacterized protein encoded by LINC00523
Search
sp|Q86TU7|SETD3_HUMAN
Histone-lysine N-methyltransferase setd3
Search
SETD3
0.52Histone-lysine N-methyltransferase
0.85GO:0010452histone H3-K36 methylation
0.85GO:0018027peptidyl-lysine dimethylation
0.85GO:0018026peptidyl-lysine monomethylation
0.85GO:0018023peptidyl-lysine trimethylation
0.57GO:0051568histone H3-K4 methylation
0.57GO:1903506regulation of nucleic acid-templated transcription
0.56GO:0051149positive regulation of muscle cell differentiation
0.54GO:1902680positive regulation of RNA biosynthetic process
0.53GO:0010628positive regulation of gene expression
0.45GO:2000112regulation of cellular macromolecule biosynthetic process
0.85GO:0046975histone methyltransferase activity (H3-K36 specific)
0.79GO:0003713transcription coactivator activity
0.58GO:0042800histone methyltransferase activity (H3-K4 specific)
0.57GO:0001102RNA polymerase II activating transcription factor binding
0.32GO:0003924GTPase activity
0.32GO:0032550purine ribonucleoside binding
0.32GO:0019001guanyl nucleotide binding
0.32GO:0032555purine ribonucleotide binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.53GO:0000790nuclear chromatin
0.34GO:0005654nucleoplasm
sp|Q86TV6|TTC7B_HUMAN
Tetratricopeptide repeat protein 7B
Search
TTC7B
0.91Tetratricopeptide repeat protein 7B
0.79GO:0072659protein localization to plasma membrane
0.72GO:0046854phosphatidylinositol phosphorylation
0.37GO:0005515protein binding
0.66GO:0005829cytosol
0.54GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q86TW2|ADCK1_HUMAN
Uncharacterized aarF domain-containing protein kinase 1
Search
ADCK1
0.96AarF domain containing kinase 1
0.59GO:0006468protein phosphorylation
0.34GO:0055088lipid homeostasis
0.34GO:0031571mitotic G1 DNA damage checkpoint
0.33GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.33GO:0007005mitochondrion organization
0.59GO:0004672protein kinase activity
0.51GO:0032559adenyl ribonucleotide binding
0.50GO:0008144drug binding
0.50GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0030332cyclin binding
0.42GO:0005739mitochondrion
0.37GO:0005576extracellular region
0.33GO:0019005SCF ubiquitin ligase complex
0.32GO:0019866organelle inner membrane
0.30GO:0016021integral component of membrane
sp|Q86TX2|ACOT1_HUMAN
Acyl-coenzyme A thioesterase 1
Search
0.54Acyl-coenzyme A thioesterase 2, mitochondrial
0.73GO:0035383thioester metabolic process
0.65GO:0032789unsaturated monocarboxylic acid metabolic process
0.65GO:0032788saturated monocarboxylic acid metabolic process
0.63GO:0006732coenzyme metabolic process
0.61GO:0000038very long-chain fatty acid metabolic process
0.59GO:0001676long-chain fatty acid metabolic process
0.54GO:0006793phosphorus metabolic process
0.53GO:0043649dicarboxylic acid catabolic process
0.53GO:0046459short-chain fatty acid metabolic process
0.37GO:0070849response to epidermal growth factor
0.76GO:0016790thiolester hydrolase activity
0.52GO:0005102receptor binding
0.47GO:0052689carboxylic ester hydrolase activity
0.55GO:0005777peroxisome
0.42GO:0005829cytosol
0.40GO:0005759mitochondrial matrix
0.40GO:0070062extracellular exosome
0.37GO:0031907microbody lumen
0.76EC:3.1.2 GO:0016790
0.47KEGG:R00630 GO:0052689
sp|Q86TY3|CN037_HUMAN
Uncharacterized protein C14orf37
Search
0.35GO:0042273ribosomal large subunit biogenesis
0.34GO:0051641cellular localization
0.34GO:0090304nucleic acid metabolic process
0.34GO:0010467gene expression
0.34GO:0006996organelle organization
0.34GO:0006275regulation of DNA replication
0.33GO:0009059macromolecule biosynthetic process
0.33GO:0045893positive regulation of transcription, DNA-templated
0.33GO:0034654nucleobase-containing compound biosynthetic process
0.33GO:0044260cellular macromolecule metabolic process
0.35GO:0003899DNA-directed 5'-3' RNA polymerase activity
0.34GO:0003677DNA binding
0.33GO:0043021ribonucleoprotein complex binding
0.32GO:0061505DNA topoisomerase II activity
0.32GO:0046982protein heterodimerization activity
0.32GO:0008144drug binding
0.32GO:0032555purine ribonucleotide binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0000991transcription factor activity, core RNA polymerase II binding
0.32GO:0008094DNA-dependent ATPase activity
0.34GO:0005634nucleus
0.33GO:0030687preribosome, large subunit precursor
0.33GO:0031974membrane-enclosed lumen
0.33GO:0042025host cell nucleus
0.33GO:0043232intracellular non-membrane-bounded organelle
0.33GO:0030123AP-3 adaptor complex
0.32GO:0044446intracellular organelle part
0.32GO:0020011apicoplast
0.32GO:0000428DNA-directed RNA polymerase complex
0.32GO:0005667transcription factor complex
0.35EC:2.7.7.6 GO:0003899
sp|Q86TZ1|TTC6_HUMAN
Tetratricopeptide repeat protein 6
Search
TTC6
0.89Tetratricopeptide repeat protein 6
sp|Q86U02|CN165_HUMAN
Putative uncharacterized protein encoded by LINC00596
Search
0.54GO:0048741skeletal muscle fiber development
0.43GO:0065007biological regulation
0.42GO:0030574collagen catabolic process
0.40GO:0019538protein metabolic process
0.39GO:0006851mitochondrial calcium ion transmembrane transport
0.39GO:0023052signaling
0.39GO:0097242amyloid-beta clearance
0.39GO:0007154cell communication
0.39GO:0070509calcium ion import
0.38GO:0050896response to stimulus
0.41GO:0005515protein binding
0.40GO:0140096catalytic activity, acting on a protein
0.40GO:0008270zinc ion binding
0.39GO:0004888transmembrane signaling receptor activity
0.39GO:0019166trans-2-enoyl-CoA reductase (NADPH) activity
0.39GO:0003676nucleic acid binding
0.38GO:00086702,4-dienoyl-CoA reductase (NADPH) activity
0.38GO:0016773phosphotransferase activity, alcohol group as acceptor
0.38GO:0008484sulfuric ester hydrolase activity
0.37GO:0016301kinase activity
0.42GO:0044421extracellular region part
0.41GO:0005829cytosol
0.39GO:0043234protein complex
0.38GO:0043227membrane-bounded organelle
0.38GO:0005887integral component of plasma membrane
0.37GO:0070013intracellular organelle lumen
0.37GO:0044446intracellular organelle part
0.36GO:0005929cilium
0.36GO:0031975envelope
0.36GO:0012505endomembrane system
0.39EC:1.3.1.38 GO:0019166
0.35KEGG:R01529 GO:0004750
sp|Q86U06|RBM23_HUMAN
Probable RNA-binding protein 23
Search
RBM23
0.97RNA binding motif protein 23
0.70GO:0006397mRNA processing
0.33GO:0055085transmembrane transport
0.59GO:0003723RNA binding
0.35GO:0005515protein binding
0.33GO:0022857transmembrane transporter activity
0.61GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
sp|Q86U10|LPP60_HUMAN
60 kDa lysophospholipase
Search
ASPG
0.43Lysophospholipase
0.56GO:0006520cellular amino acid metabolic process
0.46GO:0072329monocarboxylic acid catabolic process
0.44GO:1901565organonitrogen compound catabolic process
0.41GO:0043603cellular amide metabolic process
0.38GO:0016042lipid catabolic process
0.35GO:0007018microtubule-based movement
0.34GO:0006644phospholipid metabolic process
0.34GO:0046394carboxylic acid biosynthetic process
0.33GO:1901566organonitrogen compound biosynthetic process
0.79GO:0004067asparaginase activity
0.41GO:0004622lysophospholipase activity
0.40GO:00038471-alkyl-2-acetylglycerophosphocholine esterase activity
0.35GO:0003777microtubule motor activity
0.35GO:0008017microtubule binding
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0005829cytosol
0.30GO:0016020membrane
0.79EC:3.5.1.1 GO:0004067
sp|Q86U17|SPA11_HUMAN
Serpin A11
Search
0.78Thyroxine-binding globulin
0.53GO:0010951negative regulation of endopeptidase activity
0.47GO:0070327thyroid hormone transport
0.37GO:0008211glucocorticoid metabolic process
0.37GO:0007283spermatogenesis
0.36GO:0006508proteolysis
0.36GO:0043434response to peptide hormone
0.36GO:0061107seminal vesicle development
0.35GO:0034097response to cytokine
0.34GO:0033189response to vitamin A
0.34GO:0051412response to corticosterone
0.54GO:0004867serine-type endopeptidase inhibitor activity
0.37GO:0008289lipid binding
0.37GO:0032190acrosin binding
0.37GO:0050997quaternary ammonium group binding
0.36GO:0008233peptidase activity
0.36GO:0002020protease binding
0.36GO:0070405ammonium ion binding
0.35GO:0033293monocarboxylic acid binding
0.34GO:0015349thyroid hormone transmembrane transporter activity
0.34GO:0042562hormone binding
0.73GO:0005615extracellular space
0.37GO:1903561extracellular vesicle
0.37GO:0036025protein C inhibitor-TMPRSS11E complex
0.37GO:0097182protein C inhibitor-coagulation factor Xa complex
0.37GO:0097183protein C inhibitor-coagulation factor XI complex
0.37GO:0097181protein C inhibitor-coagulation factor V complex
0.37GO:0036030protein C inhibitor-plasma kallikrein complex
0.37GO:0036028protein C inhibitor-thrombin complex
0.37GO:0036029protein C inhibitor-KLK3 complex
0.37GO:0036024protein C inhibitor-TMPRSS7 complex
0.36EC:3.4 GO:0008233
sp|Q86U28|ISCA2_HUMAN
Iron-sulfur cluster assembly 2 homolog, mitochondrial
Search
ISCA2
0.95Iron-sulfur cluster assembly 2 like protein, mitochondrial
0.77GO:0097428protein maturation by iron-sulfur cluster transfer
0.44GO:0031163metallo-sulfur cluster assembly
0.42GO:0006790sulfur compound metabolic process
0.41GO:0051188cofactor biosynthetic process
0.33GO:0009607response to biotic stimulus
0.32GO:0044281small molecule metabolic process
0.64GO:0051540metal cluster binding
0.61GO:0005198structural molecule activity
0.55GO:0048037cofactor binding
0.41GO:0005506iron ion binding
0.33GO:0005515protein binding
0.44GO:0005739mitochondrion
0.34GO:0031974membrane-enclosed lumen
0.33GO:0044446intracellular organelle part
0.30GO:0031224intrinsic component of membrane
sp|Q86U37|CN023_HUMAN
Uncharacterized protein encoded by LINC01551
Search
sp|Q86U38|NOP9_HUMAN
Nucleolar protein 9
Search
NOP9
0.71Nucleolar protein 9
0.59GO:0003723RNA binding
sp|Q86U42|PABP2_HUMAN
Polyadenylate-binding protein 2
Search
PABPN1
0.81Polyadenylate-binding protein nuclear 1
0.86GO:1904247positive regulation of polynucleotide adenylyltransferase activity
0.48GO:0071222cellular response to lipopolysaccharide
0.47GO:0016973poly(A)+ mRNA export from nucleus
0.47GO:0000165MAPK cascade
0.44GO:0042981regulation of apoptotic process
0.43GO:0006915apoptotic process
0.41GO:0043069negative regulation of programmed cell death
0.39GO:0031124mRNA 3'-end processing
0.38GO:0043631RNA polyadenylation
0.36GO:0038034signal transduction in absence of ligand
0.59GO:0003723RNA binding
0.46GO:0070063RNA polymerase binding
0.42GO:0097718disordered domain specific binding
0.40GO:0046982protein heterodimerization activity
0.40GO:0042802identical protein binding
0.38GO:0043621protein self-association
0.50GO:0042405nuclear inclusion body
0.43GO:0097136Bcl-2 family protein complex
0.40GO:0030529intracellular ribonucleoprotein complex
0.38GO:0016607nuclear speck
0.35GO:0005741mitochondrial outer membrane
sp|Q86U44|MTA70_HUMAN
N6-adenosine-methyltransferase 70 kDa subunit
Search
METTL3
0.94Spalt like transcription factor 2
0.79GO:0080009mRNA methylation
0.65GO:1990729primary miRNA modification
0.62GO:1903679positive regulation of cap-independent translational initiation
0.57GO:0034644cellular response to UV
0.54GO:0000398mRNA splicing, via spliceosome
0.49GO:0098508endothelial to hematopoietic transition
0.48GO:1902036regulation of hematopoietic stem cell differentiation
0.48GO:0006974cellular response to DNA damage stimulus
0.47GO:0045746negative regulation of Notch signaling pathway
0.42GO:0042981regulation of apoptotic process
0.86GO:0016422mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
0.54GO:1904047S-adenosyl-L-methionine binding
0.53GO:0003729mRNA binding
0.52GO:0046982protein heterodimerization activity
0.36GO:0001734mRNA (N6-adenosine)-methyltransferase activity
0.33GO:0046872metal ion binding
0.32GO:0016787hydrolase activity
0.62GO:0036396RNA N6-methyladenosine methyltransferase complex
0.61GO:0005634nucleus
0.50GO:0031974membrane-enclosed lumen
0.45GO:0044446intracellular organelle part
0.33GO:0005737cytoplasm
0.86EC:2.1.1.62 GO:0016422
sp|Q86U70|LDB1_HUMAN
LIM domain-binding protein 1
Search
LDB1
0.96LIM domain-binding protein 1
0.71GO:0006357regulation of transcription by RNA polymerase II
0.58GO:0046985positive regulation of hemoglobin biosynthetic process
0.57GO:0045647negative regulation of erythrocyte differentiation
0.57GO:0043973histone H3-K4 acetylation
0.56GO:0021702cerebellar Purkinje cell differentiation
0.55GO:0010669epithelial structure maintenance
0.55GO:0000972transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
0.55GO:0001702gastrulation with mouth forming second
0.55GO:0035019somatic stem cell population maintenance
0.54GO:0051893regulation of focal adhesion assembly
0.86GO:0030274LIM domain binding
0.75GO:0000989transcription factor activity, transcription factor binding
0.54GO:0001102RNA polymerase II activating transcription factor binding
0.54GO:0043621protein self-association
0.54GO:0001158enhancer sequence-specific DNA binding
0.50GO:0042803protein homodimerization activity
0.50GO:0003682chromatin binding
0.48GO:0019899enzyme binding
0.61GO:0005634nucleus
0.52GO:0031252cell leading edge
0.49GO:0005667transcription factor complex
0.48GO:0000785chromatin
0.46GO:0043233organelle lumen
sp|Q86U86|PB1_HUMAN
Protein polybromo-1
Search
PBRM1
0.92Polybromo 1
0.78GO:0006338chromatin remodeling
0.68GO:0008285negative regulation of cell proliferation
0.39GO:0001890placenta development
0.39GO:0007507heart development
0.77GO:0003682chromatin binding
0.55GO:0003677DNA binding
0.83GO:0016586RSC-type complex
0.61GO:0005654nucleoplasm
0.38GO:0000776kinetochore
0.30GO:0031224intrinsic component of membrane
sp|Q86U90|YRDC_HUMAN
YrdC domain-containing protein, mitochondrial
Search
YRDC
0.96YrdC domain-containing protein, mitochondrial
0.58GO:0051051negative regulation of transport
0.47GO:0002949tRNA threonylcarbamoyladenosine modification
0.46GO:0006450regulation of translational fidelity
0.74GO:0003725double-stranded RNA binding
0.45GO:0000049tRNA binding
0.42GO:0016779nucleotidyltransferase activity
0.34GO:0005515protein binding
0.37GO:0005739mitochondrion
0.30GO:0016020membrane
0.42EC:2.7.7 GO:0016779
sp|Q86UA1|PRP39_HUMAN
Pre-mRNA-processing factor 39
Search
PRPF39
0.89Pre-mRNA-processing factor 39
0.61GO:0006396RNA processing
0.43GO:0022618ribonucleoprotein complex assembly
0.43GO:0016071mRNA metabolic process
0.49GO:0030627pre-mRNA 5'-splice site binding
0.32GO:0030554adenyl nucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0097367carbohydrate derivative binding
0.47GO:0000243commitment complex
0.46GO:0071004U2-type prespliceosome
0.46GO:0005685U1 snRNP
sp|Q86UA6|RIP_HUMAN
RPA-interacting protein
Search
RPAIN
0.95RPA interacting protein alpha
0.47GO:0009411response to UV
0.47GO:0006606protein import into nucleus
0.44GO:0006261DNA-dependent DNA replication
0.42GO:0006310DNA recombination
0.42GO:0006281DNA repair
0.45GO:0032403protein complex binding
0.39GO:0046872metal ion binding
0.82GO:0001650fibrillar center
0.49GO:0016605PML body
0.37GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q86UB2|BIVM_HUMAN
Basic immunoglobulin-like variable motif-containing protein
Search
BIVM
0.97Basic, immunoglobulin-like variable motif containing
0.52GO:0006295nucleotide-excision repair, DNA incision, 3'-to lesion
0.45GO:0003697single-stranded DNA binding
0.45GO:0004520endodeoxyribonuclease activity
0.58GO:0005634nucleus
0.58GO:0005615extracellular space
0.46GO:0005737cytoplasm
sp|Q86UB9|TM135_HUMAN
Transmembrane protein 135
Search
TMEM135
0.97Transmembrane protein 135
0.58GO:0090140regulation of mitochondrial fission
0.57GO:0032094response to food
0.53GO:0009409response to cold
0.38GO:0007031peroxisome organization
0.36GO:0010918positive regulation of mitochondrial membrane potential
0.36GO:0010884positive regulation of lipid storage
0.35GO:0008340determination of adult lifespan
0.34GO:0010628positive regulation of gene expression
0.54GO:0005811lipid droplet
0.53GO:0042579microbody
0.45GO:0005739mitochondrion
0.39GO:0098805whole membrane
0.39GO:0098588bounding membrane of organelle
0.37GO:0031967organelle envelope
0.30GO:0044425membrane part
sp|Q86UC2|RSPH3_HUMAN
Radial spoke head protein 3 homolog
Search
RSPH3
0.96Flagellar radial spoke protein 3
0.48GO:0005515protein binding
0.68GO:0042995cell projection
0.65GO:0005856cytoskeleton
0.47GO:0005737cytoplasm
sp|Q86UD0|SAPC2_HUMAN
Suppressor APC domain-containing protein 2
Search
SAPCD2
0.96Suppressor APC domain-containing protein 2
0.88GO:1904777negative regulation of protein localization to cell cortex
0.86GO:0098725symmetric cell division
0.82GO:0090175regulation of establishment of planar polarity
0.82GO:0000132establishment of mitotic spindle orientation
0.79GO:0008284positive regulation of cell proliferation
0.34GO:0035335peptidyl-tyrosine dephosphorylation
0.39GO:0005515protein binding
0.34GO:0004725protein tyrosine phosphatase activity
0.85GO:0045179apical cortex
0.80GO:0043296apical junction complex
0.73GO:0005730nucleolus
0.68GO:0005829cytosol
0.49GO:0016324apical plasma membrane
0.49GO:0070160occluding junction
0.30GO:0016021integral component of membrane
0.34EC:3.1.3.48 GO:0004725
sp|Q86UD1|OAF_HUMAN
Out at first protein homolog
Search
OAF
0.97Out at first protein homolog
0.45GO:0016321female meiosis chromosome segregation
0.44GO:0007275multicellular organism development
0.44GO:0043922negative regulation by host of viral transcription
0.40GO:0006366transcription by RNA polymerase II
0.40GO:0045944positive regulation of transcription by RNA polymerase II
0.42GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
0.62GO:0070062extracellular exosome
0.37GO:0005634nucleus
0.30GO:0016020membrane
sp|Q86UD3|MARH3_HUMAN
E3 ubiquitin-protein ligase MARCH3
Search
MARCH3
0.91Membrane associated ring-CH-type finger 3
0.45GO:0016567protein ubiquitination
0.40GO:0006897endocytosis
0.37GO:0030097hemopoiesis
0.33GO:0000398mRNA splicing, via spliceosome
0.63GO:0008270zinc ion binding
0.53GO:0016874ligase activity
0.43GO:0004842ubiquitin-protein transferase activity
0.32GO:0003723RNA binding
0.52GO:0005764lysosome
0.52GO:0031410cytoplasmic vesicle
0.49GO:0012505endomembrane system
0.40GO:0098805whole membrane
0.40GO:0098588bounding membrane of organelle
0.39GO:0012506vesicle membrane
0.37GO:0044446intracellular organelle part
0.33GO:0019013viral nucleocapsid
0.32GO:0030529intracellular ribonucleoprotein complex
0.30GO:0031224intrinsic component of membrane
0.53EC:6 GO:0016874
0.43KEGG:R03876 GO:0004842
sp|Q86UD4|ZN329_HUMAN
Zinc finger protein 329
Search
0.70zinc finger protein 329
0.51GO:1903506regulation of nucleic acid-templated transcription
0.51GO:2000112regulation of cellular macromolecule biosynthetic process
0.50GO:0010468regulation of gene expression
0.37GO:0006351transcription, DNA-templated
0.35GO:0030097hemopoiesis
0.33GO:0035556intracellular signal transduction
0.51GO:0003676nucleic acid binding
0.48GO:0046872metal ion binding
0.43GO:0003700DNA binding transcription factor activity
0.30GO:0005515protein binding
0.41GO:0005622intracellular
0.37GO:0043227membrane-bounded organelle
0.30GO:0016020membrane
sp|Q86UD5|SL9B2_HUMAN
Mitochondrial sodium/hydrogen exchanger 9B2
Search
SLC9B2
0.94Mitochondrial sodium/hydrogen exchanger NHA2
0.72GO:0006814sodium ion transport
0.62GO:1902600hydrogen ion transmembrane transport
0.55GO:2001206positive regulation of osteoclast development
0.53GO:0030317flagellated sperm motility
0.53GO:0061178regulation of insulin secretion involved in cellular response to glucose stimulus
0.47GO:0072583clathrin-dependent endocytosis
0.34GO:0007018microtubule-based movement
0.34GO:0051453regulation of intracellular pH
0.34GO:0007338single fertilization
0.33GO:0055114oxidation-reduction process
0.74GO:0015299solute:proton antiporter activity
0.50GO:0015491cation:cation antiporter activity
0.48GO:0015081sodium ion transmembrane transporter activity
0.47GO:0042802identical protein binding
0.35GO:0003777microtubule motor activity
0.35GO:0008017microtubule binding
0.33GO:0016491oxidoreductase activity
0.33GO:0030554adenyl nucleotide binding
0.33GO:0032555purine ribonucleotide binding
0.33GO:0008144drug binding
0.54GO:0097228sperm principal piece
0.54GO:0030672synaptic vesicle membrane
0.52GO:0016323basolateral plasma membrane
0.50GO:0010008endosome membrane
0.44GO:0031966mitochondrial membrane
0.38GO:0030054cell junction
0.35GO:0019866organelle inner membrane
0.35GO:0016324apical plasma membrane
0.30GO:0016021integral component of membrane
0.33EC:1 GO:0016491
sp|Q86UD7|TBC26_HUMAN
TBC1 domain family member 26
Search
0.81USP6 N-terminal like
0.75GO:0031338regulation of vesicle fusion
0.74GO:0090630activation of GTPase activity
0.63GO:0035526retrograde transport, plasma membrane to Golgi
0.62GO:0006886intracellular protein transport
0.61GO:0048227plasma membrane to endosome transport
0.61GO:1903358regulation of Golgi organization
0.56GO:0007030Golgi organization
0.51GO:0019068virion assembly
0.44GO:0016579protein deubiquitination
0.41GO:1902017regulation of cilium assembly
0.76GO:0017137Rab GTPase binding
0.72GO:0005096GTPase activator activity
0.44GO:0036459thiol-dependent ubiquitinyl hydrolase activity
0.36GO:0005516calmodulin binding
0.36GO:0004197cysteine-type endopeptidase activity
0.33GO:0003676nucleic acid binding
0.61GO:0012505endomembrane system
0.55GO:0031410cytoplasmic vesicle
0.47GO:0005886plasma membrane
0.37GO:0098588bounding membrane of organelle
0.36GO:0005764lysosome
0.35GO:0098805whole membrane
0.35GO:0044446intracellular organelle part
0.34GO:0005829cytosol
0.30GO:0016021integral component of membrane
0.44EC:3.4.19.12 GO:0036459
sp|Q86UE3|ZN546_HUMAN
Zinc finger protein 546
Search
0.66Zinc finger protein 546
0.56GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:1903506regulation of nucleic acid-templated transcription
0.56GO:0010468regulation of gene expression
0.30GO:0044237cellular metabolic process
0.30GO:0006807nitrogen compound metabolic process
0.30GO:1901360organic cyclic compound metabolic process
0.30GO:1901576organic substance biosynthetic process
0.30GO:0044238primary metabolic process
0.30GO:0043170macromolecule metabolic process
0.51GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.30GO:0140110transcription regulator activity
0.45GO:0005622intracellular
0.30GO:0044425membrane part
0.30GO:0043226organelle
sp|Q86UE4|LYRIC_HUMAN
Protein LYRIC
Search
MTDH
0.97Metadherin a
0.84GO:0045766positive regulation of angiogenesis
0.84GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.78GO:0043066negative regulation of apoptotic process
0.61GO:0031663lipopolysaccharide-mediated signaling pathway
0.60GO:0051897positive regulation of protein kinase B signaling
0.59GO:0051092positive regulation of NF-kappaB transcription factor activity
0.57GO:0010508positive regulation of autophagy
0.56GO:0000122negative regulation of transcription by RNA polymerase II
0.43GO:0070830bicellular tight junction assembly
0.62GO:0051059NF-kappaB binding
0.59GO:0001085RNA polymerase II transcription factor binding
0.57GO:0003713transcription coactivator activity
0.55GO:0003725double-stranded RNA binding
0.60GO:0001650fibrillar center
0.57GO:0048471perinuclear region of cytoplasm
0.56GO:0016604nuclear body
0.53GO:0005783endoplasmic reticulum
0.53GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.50GO:0031984organelle subcompartment
0.44GO:0046581intercellular canaliculus
0.42GO:0016324apical plasma membrane
0.42GO:0005923bicellular tight junction
0.40GO:0031965nuclear membrane
sp|Q86UE6|LRRT1_HUMAN
Leucine-rich repeat transmembrane neuronal protein 1
Search
LRRTM1
0.97Leucine-rich repeat transmembrane neuronal protein 1
0.54GO:0051965positive regulation of synapse assembly
0.52GO:0046426negative regulation of JAK-STAT cascade
0.52GO:0002091negative regulation of receptor internalization
0.50GO:0035418protein localization to synapse
0.50GO:0035640exploration behavior
0.50GO:0060291long-term synaptic potentiation
0.50GO:0006469negative regulation of protein kinase activity
0.49GO:0019221cytokine-mediated signaling pathway
0.49GO:1902004positive regulation of amyloid-beta formation
0.48GO:0007626locomotory behavior
0.51GO:0004860protein kinase inhibitor activity
0.40GO:0042802identical protein binding
0.53GO:0030426growth cone
0.51GO:0030424axon
0.47GO:0005783endoplasmic reticulum
0.41GO:0045211postsynaptic membrane
0.40GO:0030054cell junction
0.39GO:0060076excitatory synapse
0.36GO:0009986cell surface
0.30GO:0016021integral component of membrane
sp|Q86UE8|TLK2_HUMAN
Serine/threonine-protein kinase tousled-like 2
Search
TLK2
0.76Tousled like kinase 2
0.62GO:0006468protein phosphorylation
0.55GO:0071480cellular response to gamma radiation
0.55GO:0001672regulation of chromatin assembly or disassembly
0.55GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.52GO:0018209peptidyl-serine modification
0.48GO:0007059chromosome segregation
0.45GO:0006974cellular response to DNA damage stimulus
0.44GO:0035556intracellular signal transduction
0.36GO:0016569covalent chromatin modification
0.35GO:0010507negative regulation of autophagy
0.69GO:0004674protein serine/threonine kinase activity
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.34GO:0005515protein binding
0.60GO:0005634nucleus
0.51GO:0048471perinuclear region of cytoplasm
0.51GO:0005882intermediate filament
0.69EC:2.7.11 GO:0004674
sp|Q86UF1|TSN33_HUMAN
Tetraspanin-33
Search
TSPAN33
0.57Tetraspanin
0.54GO:0072659protein localization to plasma membrane
0.49GO:0051604protein maturation
0.46GO:0007166cell surface receptor signaling pathway
0.35GO:0007275multicellular organism development
0.33GO:1903506regulation of nucleic acid-templated transcription
0.33GO:2000112regulation of cellular macromolecule biosynthetic process
0.33GO:0010468regulation of gene expression
0.33GO:0072594establishment of protein localization to organelle
0.32GO:0016255attachment of GPI anchor to protein
0.49GO:0019899enzyme binding
0.35GO:0004888transmembrane signaling receptor activity
0.56GO:0097197tetraspanin-enriched microdomain
0.50GO:0009986cell surface
0.44GO:0005887integral component of plasma membrane
0.33GO:0005634nucleus
0.32GO:0042765GPI-anchor transamidase complex
sp|Q86UF2|CTGE6_HUMAN
cTAGE family member 6
Search
0.83Cutaneous T-cell lymphoma-associated antigen 1
0.30GO:0044425membrane part
sp|Q86UF4|CC190_HUMAN
Coiled-coil domain-containing protein 190
Search
CCDC190
0.62Coiled-coil domain-containing protein 190
sp|Q86UG4|SO6A1_HUMAN
Solute carrier organic anion transporter family member 6A1
Search
0.61Testis-specific transporter TST-2
0.58GO:0043252sodium-independent organic anion transport
0.55GO:0055085transmembrane transport
0.39GO:0007283spermatogenesis
0.37GO:0030154cell differentiation
0.37GO:0007275multicellular organism development
0.35GO:0043312neutrophil degranulation
0.32GO:0043043peptide biosynthetic process
0.31GO:0044267cellular protein metabolic process
0.31GO:0010467gene expression
0.31GO:0009059macromolecule biosynthetic process
0.58GO:0015347sodium-independent organic anion transmembrane transporter activity
0.32GO:0003735structural constituent of ribosome
0.54GO:0005886plasma membrane
0.36GO:0070062extracellular exosome
0.36GO:0035579specific granule membrane
0.36GO:0035577azurophil granule membrane
0.32GO:0005840ribosome
0.30GO:0016021integral component of membrane
sp|Q86UK0|ABCAC_HUMAN
ATP-binding cassette sub-family A member 12
Search
ABCA12
0.93ATP-binding cassette sub-family A member 12
0.74GO:0006869lipid transport
0.71GO:0043129surfactant homeostasis
0.71GO:0010875positive regulation of cholesterol efflux
0.70GO:2000010positive regulation of protein localization to cell surface
0.69GO:0061436establishment of skin barrier
0.69GO:0031424keratinization
0.68GO:0048286lung alveolus development
0.66GO:0072659protein localization to plasma membrane
0.66GO:0045055regulated exocytosis
0.65GO:0055088lipid homeostasis
0.73GO:0034191apolipoprotein A-I receptor binding
0.66GO:0042626ATPase activity, coupled to transmembrane movement of substances
0.62GO:0005319lipid transporter activity
0.55GO:0030554adenyl nucleotide binding
0.54GO:0097367carbohydrate derivative binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.54GO:0008144drug binding
0.33GO:0034188apolipoprotein A-I receptor activity
0.72GO:0097209epidermal lamellar body
0.56GO:0005829cytosol
0.51GO:0031966mitochondrial membrane
0.51GO:0019866organelle inner membrane
0.47GO:0005886plasma membrane
0.32GO:0030054cell junction
0.32GO:0005794Golgi apparatus
0.32GO:0001726ruffle
0.31GO:0045177apical part of cell
0.31GO:0010008endosome membrane
sp|Q86UK5|LBN_HUMAN
Limbin
Search
EVC2
0.97EvC ciliary complex subunit 2
0.84GO:0007224smoothened signaling pathway
0.78GO:0060170ciliary membrane
0.61GO:0098797plasma membrane protein complex
0.57GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
sp|Q86UK7|ZN598_HUMAN
E3 ubiquitin-protein ligase ZNF598
Search
ZNF598
0.86LOW QUALITY PROTEIN: zinc finger protein 598
0.41GO:0072344rescue of stalled ribosome
0.40GO:0006513protein monoubiquitination
0.51GO:0003676nucleic acid binding
0.39GO:0061630ubiquitin protein ligase activity
0.39GO:0043022ribosome binding
0.35GO:0016874ligase activity
0.34GO:0046872metal ion binding
0.34GO:0005515protein binding
0.35EC:6 GO:0016874
sp|Q86UL3|GPAT4_HUMAN
Glycerol-3-phosphate acyltransferase 4
Search
GPAT4
0.93Glycerol-3-phosphate acyltransferase 4
0.59GO:0002071glandular epithelial cell maturation
0.57GO:0046339diacylglycerol metabolic process
0.55GO:0006656phosphatidylcholine biosynthetic process
0.54GO:0040014regulation of multicellular organism growth
0.54GO:0019432triglyceride biosynthetic process
0.53GO:0007595lactation
0.50GO:0035383thioester metabolic process
0.47GO:0006631fatty acid metabolic process
0.45GO:0006732coenzyme metabolic process
0.39GO:0016024CDP-diacylglycerol biosynthetic process
0.62GO:0016746transferase activity, transferring acyl groups
0.49GO:0005783endoplasmic reticulum
0.39GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.38GO:0031984organelle subcompartment
0.30GO:0016021integral component of membrane
0.62EC:2.3 GO:0016746
sp|Q86UL8|MAGI2_HUMAN
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Search
MAGI2
0.91Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
0.59GO:0032926negative regulation of activin receptor signaling pathway
0.58GO:0007165signal transduction
0.57GO:0043113receptor clustering
0.57GO:0032516positive regulation of phosphoprotein phosphatase activity
0.56GO:0002092positive regulation of receptor internalization
0.56GO:2000809positive regulation of synaptic vesicle clustering
0.55GO:0051898negative regulation of protein kinase B signaling
0.55GO:0097104postsynaptic membrane assembly
0.50GO:0072015glomerular visceral epithelial cell development
0.50GO:0071850mitotic cell cycle arrest
0.76GO:0032947protein complex scaffold activity
0.60GO:0070699type II activin receptor binding
0.59GO:0031697beta-1 adrenergic receptor binding
0.56GO:0046332SMAD binding
0.53GO:0019902phosphatase binding
0.51GO:0016301kinase activity
0.46GO:0004871signal transducer activity
0.36GO:0019894kinesin binding
0.35GO:0032403protein complex binding
0.32GO:0008270zinc ion binding
0.76GO:0005923bicellular tight junction
0.52GO:0097458neuron part
0.51GO:0036057slit diaphragm
0.49GO:0120038plasma membrane bounded cell projection part
0.48GO:0032279asymmetric synapse
0.48GO:0099572postsynaptic specialization
0.47GO:0048471perinuclear region of cytoplasm
0.44GO:0005634nucleus
0.42GO:0005886plasma membrane
0.39GO:0005770late endosome
sp|Q86UN2|R4RL1_HUMAN
Reticulon-4 receptor-like 1
Search
RTN4RL1
0.97Reticulon 4 receptor like 1
0.76GO:0022038corpus callosum development
0.73GO:0048681negative regulation of axon regeneration
0.60GO:0046426negative regulation of JAK-STAT cascade
0.57GO:0006469negative regulation of protein kinase activity
0.56GO:0019221cytokine-mediated signaling pathway
0.46GO:0048922posterior lateral line neuromast deposition
0.41GO:0031103axon regeneration
0.39GO:0006501C-terminal protein lipidation
0.75GO:0035374chondroitin sulfate binding
0.68GO:0008201heparin binding
0.58GO:0004860protein kinase inhibitor activity
0.56GO:0004872receptor activity
0.39GO:0005515protein binding
0.70GO:0046658anchored component of plasma membrane
0.65GO:0009986cell surface
0.46GO:0043204perikaryon
0.44GO:0045121membrane raft
0.43GO:0098552side of membrane
0.41GO:0070062extracellular exosome
0.41GO:0042995cell projection
0.40GO:0005737cytoplasm
0.30GO:0016021integral component of membrane
sp|Q86UN3|R4RL2_HUMAN
Reticulon-4 receptor-like 2
Search
0.82Reticulon 4 receptor like 2
0.81GO:0022038corpus callosum development
0.77GO:0010977negative regulation of neuron projection development
0.63GO:0046426negative regulation of JAK-STAT cascade
0.61GO:0048679regulation of axon regeneration
0.60GO:0006469negative regulation of protein kinase activity
0.60GO:1903035negative regulation of response to wounding
0.59GO:0019221cytokine-mediated signaling pathway
0.58GO:0032102negative regulation of response to external stimulus
0.46GO:0031103axon regeneration
0.42GO:0006501C-terminal protein lipidation
0.63GO:0035374chondroitin sulfate binding
0.61GO:0004860protein kinase inhibitor activity
0.59GO:0004872receptor activity
0.58GO:0008201heparin binding
0.41GO:0005515protein binding
0.74GO:0046658anchored component of plasma membrane
0.69GO:0009986cell surface
0.49GO:0043204perikaryon
0.47GO:0045121membrane raft
0.46GO:0098552side of membrane
0.45GO:0030425dendrite
0.45GO:0030424axon
0.44GO:0070062extracellular exosome
0.41GO:0005737cytoplasm
0.30GO:0016021integral component of membrane
sp|Q86UN6|AKA28_HUMAN
A-kinase anchor protein 14
Search
AKAP14
0.90A-kinase anchoring protein 14
0.47GO:0016310phosphorylation
0.41GO:0007283spermatogenesis
0.80GO:0034237protein kinase A regulatory subunit binding
0.48GO:0016301kinase activity
0.77GO:0005952cAMP-dependent protein kinase complex
0.75GO:0005930axoneme
0.43GO:0035686sperm fibrous sheath
sp|Q86UP0|CAD24_HUMAN
Cadherin-24
Search
0.55Cadherin 8
0.78GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.30GO:0034332adherens junction organization
0.70GO:0005509calcium ion binding
0.30GO:0005515protein binding
0.55GO:0005886plasma membrane
0.30GO:0030054cell junction
0.30GO:0044425membrane part
sp|Q86UP2|KTN1_HUMAN
Kinectin
Search
KTN1
0.91Kinectin 1 (Kinesin receptor)
0.74GO:0007018microtubule-based movement
0.50GO:0015031protein transport
0.37GO:0043687post-translational protein modification
0.85GO:0019894kinesin binding
0.60GO:0045296cadherin binding
0.34GO:0003723RNA binding
0.61GO:0005783endoplasmic reticulum
0.54GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.52GO:0031984organelle subcompartment
0.35GO:0043233organelle lumen
0.35GO:0005887integral component of plasma membrane
0.32GO:0070382exocytic vesicle
sp|Q86UP3|ZFHX4_HUMAN
Zinc finger homeobox protein 4
Search
ZFHX4
0.86LOW QUALITY PROTEIN: zinc finger homeobox protein 4
0.56GO:1903506regulation of nucleic acid-templated transcription
0.56GO:2000112regulation of cellular macromolecule biosynthetic process
0.55GO:0010468regulation of gene expression
0.37GO:0097659nucleic acid-templated transcription
0.36GO:0010467gene expression
0.36GO:0034645cellular macromolecule biosynthetic process
0.63GO:0043565sequence-specific DNA binding
0.62GO:0008270zinc ion binding
0.60GO:0005634nucleus
sp|Q86UP6|CUZD1_HUMAN
CUB and zona pellucida-like domain-containing protein 1
Search
CUZD1
0.95CUB and zona pellucida like domains 1
0.49GO:0032023trypsinogen activation
0.44GO:0006931substrate-dependent cell migration, cell attachment to substrate
0.40GO:0008283cell proliferation
0.40GO:0007565female pregnancy
0.39GO:0009755hormone-mediated signaling pathway
0.38GO:0051301cell division
0.38GO:0007049cell cycle
0.35GO:0006955immune response
0.35GO:0006898receptor-mediated endocytosis
0.35GO:0005044scavenger receptor activity
0.35GO:0001871pattern binding
0.34GO:0030246carbohydrate binding
0.47GO:0042589zymogen granule membrane
0.43GO:0030658transport vesicle membrane
0.30GO:0031224intrinsic component of membrane
sp|Q86UP8|GTD2A_HUMAN
General transcription factor II-I repeat domain-containing protein 2A
Search
0.75GTF2I repeat domain containing 2B
0.58GO:0097659nucleic acid-templated transcription
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.54GO:0010467gene expression
0.53GO:0034645cellular macromolecule biosynthetic process
0.55GO:0003677DNA binding
0.61GO:0005634nucleus
sp|Q86UP9|LHPL3_HUMAN
Lipoma HMGIC fusion partner-like 3 protein
Search
LHFPL3
0.86LHFPL tetraspan subfamily member 3
0.30GO:0044425membrane part
sp|Q86UQ0|ZN589_HUMAN
Zinc finger protein 589
Search
ZNF589
0.97LOW QUALITY PROTEIN: zinc finger protein 589
0.54GO:2001141regulation of RNA biosynthetic process
0.54GO:2000112regulation of cellular macromolecule biosynthetic process
0.53GO:0010468regulation of gene expression
0.41GO:0051253negative regulation of RNA metabolic process
0.41GO:0010558negative regulation of macromolecule biosynthetic process
0.41GO:0031327negative regulation of cellular biosynthetic process
0.40GO:0044140negative regulation of growth of symbiont on or near host surface
0.40GO:0051873killing by host of symbiont cells
0.39GO:0044130negative regulation of growth of symbiont in host
0.39GO:0061844antimicrobial humoral immune response mediated by antimicrobial peptide
0.51GO:0003676nucleic acid binding
0.50GO:0046872metal ion binding
0.45GO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.39GO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34GO:0005515protein binding
0.33GO:0004672protein kinase activity
0.33GO:0008168methyltransferase activity
0.33GO:0005524ATP binding
0.43GO:0005622intracellular
0.43GO:0031974membrane-enclosed lumen
0.41GO:0043227membrane-bounded organelle
0.39GO:0044422organelle part
0.36GO:0012505endomembrane system
0.36GO:0005576extracellular region
0.36GO:0043228non-membrane-bounded organelle
0.30GO:0031224intrinsic component of membrane
0.33EC:2.1.1 GO:0008168
sp|Q86UQ4|ABCAD_HUMAN
ATP-binding cassette sub-family A member 13
Search
ABCA13
0.86LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 13
0.57GO:0006869lipid transport
0.55GO:0055085transmembrane transport
0.45GO:0045055regulated exocytosis
0.44GO:0002283neutrophil activation involved in immune response
0.44GO:0002446neutrophil mediated immunity
0.40GO:0043129surfactant homeostasis
0.40GO:0010875positive regulation of cholesterol efflux
0.40GO:2000010positive regulation of protein localization to cell surface
0.40GO:0008544epidermis development
0.40GO:0061436establishment of skin barrier
0.66GO:0042626ATPase activity, coupled to transmembrane movement of substances
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.41GO:0034191apolipoprotein A-I receptor binding
0.38GO:0005319lipid transporter activity
0.45GO:0035577azurophil granule membrane
0.40GO:0097209epidermal lamellar body
0.38GO:0005886plasma membrane
0.36GO:0005829cytosol
0.35GO:0031966mitochondrial membrane
0.35GO:0019866organelle inner membrane
0.32GO:0005768endosome
0.30GO:0031224intrinsic component of membrane
sp|Q86UQ5|GTSC1_HUMAN
Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein
Search
0.22Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein
0.30GO:0044425membrane part
sp|Q86UQ8|NFE4_HUMAN
Transcription factor NF-E4
Search
NFE4
0.95Transcription factor NF-E4
0.75GO:0045944positive regulation of transcription by RNA polymerase II
0.69GO:0006461protein complex assembly
0.58GO:0006351transcription, DNA-templated
0.79GO:0000987proximal promoter sequence-specific DNA binding
0.75GO:0042803protein homodimerization activity
0.61GO:0003700DNA binding transcription factor activity
0.61GO:0005634nucleus
0.59GO:0043234protein complex
sp|Q86UR1|NOXA1_HUMAN
NADPH oxidase activator 1
Search
NOXA1
0.90NADPH oxidase activator 1
0.75GO:0006801superoxide metabolic process
0.69GO:0060263regulation of respiratory burst
0.68GO:0010310regulation of hydrogen peroxide metabolic process
0.57GO:0043085positive regulation of catalytic activity
0.35GO:0007015actin filament organization
0.35GO:0007155cell adhesion
0.68GO:0016176superoxide-generating NADPH oxidase activator activity
0.66GO:0048365Rac GTPase binding
0.62GO:0017124SH3 domain binding
0.85GO:0043020NADPH oxidase complex
0.38GO:0005829cytosol
sp|Q86UR5|RIMS1_HUMAN
Regulating synaptic membrane exocytosis protein 1
Search
RIMS1
0.82Regulating synaptic membrane exocytosis protein 1
0.77GO:0006887exocytosis
0.57GO:1903861positive regulation of dendrite extension
0.53GO:0046907intracellular transport
0.51GO:0034613cellular protein localization
0.49GO:2000300regulation of synaptic vesicle exocytosis
0.49GO:0015031protein transport
0.48GO:0097480establishment of synaptic vesicle localization
0.48GO:0099504synaptic vesicle cycle
0.48GO:0099003vesicle-mediated transport in synapse
0.48GO:0099643signal release from synapse
0.81GO:0017137Rab GTPase binding
0.50GO:0046872metal ion binding
0.48GO:0044325ion channel binding
0.36GO:0030695GTPase regulator activity
0.35GO:0003723RNA binding
0.35GO:0017124SH3 domain binding
0.34GO:0019901protein kinase binding
0.83GO:0048786presynaptic active zone
0.40GO:0042734presynaptic membrane
0.38GO:0005622intracellular
0.38GO:0030054cell junction
0.37GO:0060077inhibitory synapse
0.36GO:0014069postsynaptic density
0.35GO:0031982vesicle
0.30GO:0016021integral component of membrane
sp|Q86US8|EST1A_HUMAN
Telomerase-binding protein EST1A
Search
SMG6
0.92Smg-6 homolog, nonsense mediated mRNA decay factor
0.85GO:1904354negative regulation of telomere capping
0.83GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.67GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
0.62GO:0007004telomere maintenance via telomerase
0.60GO:0043487regulation of RNA stability
0.58GO:0071427mRNA-containing ribonucleoprotein complex export from nucleus
0.56GO:0051028mRNA transport
0.55GO:0006405RNA export from nucleus
0.48GO:0043009chordate embryonic development
0.43GO:0010467gene expression
0.85GO:0070034telomerase RNA binding
0.85GO:0070182DNA polymerase binding
0.79GO:0042162telomeric DNA binding
0.71GO:0043021ribonucleoprotein complex binding
0.68GO:0004521endoribonuclease activity
0.85GO:0000333telomerase catalytic core complex
0.82GO:0035145exon-exon junction complex
0.70GO:0005730nucleolus
0.66GO:0005829cytosol
sp|Q86UT5|NHRF4_HUMAN
Na(+)/H(+) exchange regulatory cofactor NHE-RF4
Search
PDZD3
0.97PDZ domain-containing protein 2 variant 1
0.87GO:0031283negative regulation of guanylate cyclase activity
0.86GO:0007168receptor guanylyl cyclase signaling pathway
0.58GO:0006811ion transport
0.40GO:0019934cGMP-mediated signaling
0.39GO:0006833water transport
0.36GO:0009636response to toxic substance
0.34GO:0016567protein ubiquitination
0.34GO:0023051regulation of signaling
0.33GO:0006508proteolysis
0.87GO:0010852cyclase inhibitor activity
0.86GO:0030249guanylate cyclase regulator activity
0.74GO:0004857enzyme inhibitor activity
0.68GO:1990381ubiquitin-specific protease binding
0.64GO:0008022protein C-terminus binding
0.39GO:0008200ion channel inhibitor activity
0.38GO:0001784phosphotyrosine residue binding
0.35GO:0004871signal transducer activity
0.35GO:0005509calcium ion binding
0.34GO:0004842ubiquitin-protein transferase activity
0.69GO:0035003subapical complex
0.65GO:0005903brush border
0.62GO:0045177apical part of cell
0.36GO:0005829cytosol
0.35GO:0005634nucleus
0.32GO:0042597periplasmic space
0.30GO:0016021integral component of membrane
0.34EC:3.6.1.3 GO:0016887
0.34KEGG:R03876 GO:0004842
sp|Q86UT6|NLRX1_HUMAN
NLR family member X1
Search
NLRX1
0.97NLR family member X1
0.77GO:0039536negative regulation of RIG-I signaling pathway
0.77GO:0032688negative regulation of interferon-beta production
0.74GO:0032715negative regulation of interleukin-6 production
0.73GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling
0.72GO:0050728negative regulation of inflammatory response
0.63GO:0045824negative regulation of innate immune response
0.44GO:0045087innate immune response
0.39GO:0016032viral process
0.37GO:0007166cell surface receptor signaling pathway
0.51GO:0032559adenyl ribonucleotide binding
0.50GO:0008144drug binding
0.50GO:0035639purine ribonucleoside triphosphate binding
0.39GO:0005515protein binding
0.36GO:0005509calcium ion binding
0.36GO:0016887ATPase activity
0.35GO:0004871signal transducer activity
0.65GO:0030054cell junction
0.54GO:0005739mitochondrion
0.50GO:0005886plasma membrane
0.43GO:0031968organelle outer membrane
0.35GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
0.36EC:3.6.1.3 GO:0016887
sp|Q86UT8|CCD84_HUMAN
Coiled-coil domain-containing protein 84
Search
CCDC84
0.97Coiled-coil domain-containing protein 84
0.49GO:2000112regulation of cellular macromolecule biosynthetic process
0.49GO:1903506regulation of nucleic acid-templated transcription
0.48GO:0010468regulation of gene expression
0.39GO:0006351transcription, DNA-templated
0.51GO:0043565sequence-specific DNA binding
0.49GO:0003700DNA binding transcription factor activity
0.52GO:0005634nucleus
0.46GO:0034708methyltransferase complex
0.43GO:0043233organelle lumen
0.40GO:0044446intracellular organelle part
sp|Q86UU0|BCL9L_HUMAN
B-cell CLL/lymphoma 9-like protein
Search
BCL9L
0.76B-cell CLL/lymphoma 9 like
0.84GO:0060070canonical Wnt signaling pathway
0.57GO:1903506regulation of nucleic acid-templated transcription
0.56GO:0035019somatic stem cell population maintenance
0.56GO:0035914skeletal muscle cell differentiation
0.55GO:0010718positive regulation of epithelial to mesenchymal transition
0.54GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway
0.50GO:1902680positive regulation of RNA biosynthetic process
0.49GO:0010628positive regulation of gene expression
0.47GO:0022604regulation of cell morphogenesis
0.42GO:2000112regulation of cellular macromolecule biosynthetic process
0.84GO:0008013beta-catenin binding
0.79GO:0003713transcription coactivator activity
0.57GO:1990907beta-catenin-TCF complex
0.49GO:0005730nucleolus
0.47GO:0005654nucleoplasm
0.37GO:0005801cis-Golgi network
0.36GO:0005794Golgi apparatus
sp|Q86UU1|PHLB1_HUMAN
Pleckstrin homology-like domain family B member 1
Search
PHLDB1
0.93Pleckstrin homology like domain family B member 1
0.87GO:1904261positive regulation of basement membrane assembly involved in embryonic body morphogenesis
0.85GO:0010470regulation of gastrulation
0.85GO:0010717regulation of epithelial to mesenchymal transition
0.81GO:0070507regulation of microtubule cytoskeleton organization
0.86GO:0045180basal cortex
sp|Q86UU5|GGN_HUMAN
Gametogenetin
Search
GGN
0.97Gametogenetin
0.77GO:0007276gamete generation
0.75GO:0006302double-strand break repair
0.45GO:0007566embryo implantation
0.44GO:0030154cell differentiation
0.39GO:0008104protein localization
0.37GO:0006461protein complex assembly
0.34GO:0045010actin nucleation
0.34GO:0006402mRNA catabolic process
0.33GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
0.33GO:0006364rRNA processing
0.42GO:0031625ubiquitin protein ligase binding
0.40GO:0046983protein dimerization activity
0.34GO:0008995ribonuclease E activity
0.34GO:0008092cytoskeletal protein binding
0.33GO:0004521endoribonuclease activity
0.33GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds
0.33GO:0000287magnesium ion binding
0.33GO:0008270zinc ion binding
0.33GO:0005201extracellular matrix structural constituent
0.33GO:0003723RNA binding
0.42GO:0048471perinuclear region of cytoplasm
0.41GO:0005730nucleolus
0.38GO:0005635nuclear envelope
0.37GO:0031410cytoplasmic vesicle
0.34GO:0005884actin filament
0.34GO:0009898cytoplasmic side of plasma membrane
0.32GO:0009360DNA polymerase III complex
0.32GO:0045111intermediate filament cytoskeleton
0.32GO:0031968organelle outer membrane
0.32GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.33EC:3.2.1 GO:0004553
sp|Q86UU9|TKN4_HUMAN
Tachykinin-4
Search
TAC4
0.94Tachykinin precursor 1
0.85GO:0007217tachykinin receptor signaling pathway
0.69GO:1902093positive regulation of flagellated sperm motility
0.56GO:0007204positive regulation of cytosolic calcium ion concentration
0.55GO:0006954inflammatory response
0.52GO:0007267cell-cell signaling
0.45GO:1904057negative regulation of sensory perception of pain
0.45GO:1904058positive regulation of sensory perception of pain
0.44GO:0008217regulation of blood pressure
0.44GO:0019233sensory perception of pain
0.44GO:0050961detection of temperature stimulus involved in sensory perception
0.50GO:0005102receptor binding
0.42GO:0030545receptor regulator activity
0.60GO:0005615extracellular space
0.38GO:0042629mast cell granule
0.35GO:0043025neuronal cell body
0.35GO:0030424axon
sp|Q86UV5|UBP48_HUMAN
Ubiquitin carboxyl-terminal hydrolase 48
Search
USP48
0.95Ubiquitin carboxyl-terminal hydrolase 48
0.76GO:0016579protein deubiquitination
0.72GO:0006511ubiquitin-dependent protein catabolic process
0.44GO:1904888cranial skeletal system development
0.34GO:0051056regulation of small GTPase mediated signal transduction
0.34GO:0043547positive regulation of GTPase activity
0.79GO:0004843thiol-dependent ubiquitin-specific protease activity
0.35GO:0005509calcium ion binding
0.34GO:0005096GTPase activator activity
0.48GO:0005654nucleoplasm
0.48GO:0005829cytosol
0.44GO:0005739mitochondrion
0.35GO:0045121membrane raft
0.35GO:0045211postsynaptic membrane
sp|Q86UV6|TRI74_HUMAN
Tripartite motif-containing protein 74
Search
0.86Tripartite motif-containing protein 74
0.55GO:0070201regulation of establishment of protein localization
0.37GO:0016567protein ubiquitination
0.35GO:0039023pronephric duct morphogenesis
0.35GO:0070121Kupffer's vesicle development
0.35GO:0032402melanosome transport
0.35GO:0007369gastrulation
0.34GO:0032259methylation
0.33GO:0051260protein homooligomerization
0.33GO:0046598positive regulation of viral entry into host cell
0.33GO:0051092positive regulation of NF-kappaB transcription factor activity
0.62GO:0008270zinc ion binding
0.46GO:0016874ligase activity
0.39GO:0042802identical protein binding
0.37GO:0004842ubiquitin-protein transferase activity
0.34GO:0008168methyltransferase activity
0.34GO:0003723RNA binding
0.33GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.60GO:0016235aggresome
0.42GO:0005829cytosol
0.30GO:0016020membrane
0.46EC:6 GO:0016874
0.37KEGG:R03876 GO:0004842
sp|Q86UV7|TRI73_HUMAN
Tripartite motif-containing protein 73
Search
0.86Tripartite motif-containing protein 73
0.55GO:0070201regulation of establishment of protein localization
0.37GO:0016567protein ubiquitination
0.35GO:0039023pronephric duct morphogenesis
0.35GO:0070121Kupffer's vesicle development
0.35GO:0032402melanosome transport
0.35GO:0007369gastrulation
0.34GO:0032259methylation
0.33GO:0051260protein homooligomerization
0.33GO:0046598positive regulation of viral entry into host cell
0.33GO:0051092positive regulation of NF-kappaB transcription factor activity
0.62GO:0008270zinc ion binding
0.46GO:0016874ligase activity
0.39GO:0042802identical protein binding
0.37GO:0004842ubiquitin-protein transferase activity
0.34GO:0008168methyltransferase activity
0.34GO:0003723RNA binding
0.33GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.60GO:0016235aggresome
0.42GO:0005829cytosol
0.30GO:0016020membrane
0.46EC:6 GO:0016874
0.37KEGG:R03876 GO:0004842
sp|Q86UW1|OSTA_HUMAN
Organic solute transporter subunit alpha
Search
SLC51A
0.97Organic solute transporter subunit alpha
0.65GO:0032782bile acid secretion
0.64GO:0015721bile acid and bile salt transport
0.44GO:0055085transmembrane transport
0.63GO:0015125bile acid transmembrane transporter activity
0.56GO:0042803protein homodimerization activity
0.55GO:0046982protein heterodimerization activity
0.59GO:0016323basolateral plasma membrane
0.54GO:0005789endoplasmic reticulum membrane
0.47GO:0043234protein complex
0.30GO:0016021integral component of membrane
sp|Q86UW2|OSTB_HUMAN
Organic solute transporter subunit beta
Search
SLC51B
0.97Organic solute transporter subunit beta
0.86GO:0015721bile acid and bile salt transport
0.81GO:0032782bile acid secretion
0.79GO:0060050positive regulation of protein glycosylation
0.78GO:0070863positive regulation of protein exit from endoplasmic reticulum
0.77GO:0090314positive regulation of protein targeting to membrane
0.69GO:0031647regulation of protein stability
0.50GO:0055085transmembrane transport
0.77GO:0015125bile acid transmembrane transporter activity
0.74GO:0046982protein heterodimerization activity
0.73GO:0016323basolateral plasma membrane
0.53GO:0043234protein complex
0.30GO:0016021integral component of membrane
tr|Q86UW5|Q86UW5_HUMAN
Putative uncharacterized protein HSPC047
Search
0.44Ras GTPase-activating protein 4
sp|Q86UW6|N4BP2_HUMAN
NEDD4-binding protein 2
Search
N4BP2
0.93NEDD4-binding protein 2
0.63GO:0090305nucleic acid phosphodiester bond hydrolysis
0.57GO:0016310phosphorylation
0.86GO:0046404ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
0.65GO:0004519endonuclease activity
0.54GO:0030554adenyl nucleotide binding
0.53GO:0032553ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.43GO:0005515protein binding
0.67GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
0.86EC:2.7.1.78 GO:0046404
0.86KEGG:R03840 GO:0046404
sp|Q86UW7|CAPS2_HUMAN
Calcium-dependent secretion activator 2
Search
CADPS2
0.85Calcium dependent secretion activator
0.85GO:1990504dense core granule exocytosis
0.83GO:0016079synaptic vesicle exocytosis
0.58GO:0045921positive regulation of exocytosis
0.56GO:0140029exocytic process
0.54GO:0009267cellular response to starvation
0.51GO:0043623cellular protein complex assembly
0.38GO:0050432catecholamine secretion
0.37GO:0016050vesicle organization
0.36GO:0015031protein transport
0.38GO:0008289lipid binding
0.36GO:0019901protein kinase binding
0.34GO:0046872metal ion binding
0.78GO:0098793presynapse
0.55GO:0045211postsynaptic membrane
0.52GO:0031410cytoplasmic vesicle
0.50GO:0005654nucleoplasm
0.38GO:0012506vesicle membrane
0.38GO:0030054cell junction
0.34GO:0012505endomembrane system
sp|Q86UW8|HPLN4_HUMAN
Hyaluronan and proteoglycan link protein 4
Search
HAPLN4
0.94Hyaluronan and proteoglycan link protein 4
0.71GO:0007155cell adhesion
0.50GO:0001501skeletal system development
0.49GO:0007417central nervous system development
0.37GO:0008065establishment of blood-nerve barrier
0.36GO:0085029extracellular matrix assembly
0.34GO:0002040sprouting angiogenesis
0.83GO:0005540hyaluronic acid binding
0.51GO:0005201extracellular matrix structural constituent
0.34GO:0042802identical protein binding
0.50GO:0005578proteinaceous extracellular matrix
0.33GO:0005615extracellular space
0.30GO:0031224intrinsic component of membrane
sp|Q86UW9|DTX2_HUMAN
Probable E3 ubiquitin-protein ligase DTX2
Search
DTX2
0.96Deltex E3 ubiquitin ligase 2
0.56GO:0007219Notch signaling pathway
0.37GO:0016567protein ubiquitination
0.34GO:0045581negative regulation of T cell differentiation
0.34GO:1990823response to leukemia inhibitory factor
0.34GO:0008593regulation of Notch signaling pathway
0.34GO:0045665negative regulation of neuron differentiation
0.34GO:0010001glial cell differentiation
0.34GO:0071345cellular response to cytokine stimulus
0.61GO:0008270zinc ion binding
0.49GO:0016874ligase activity
0.36GO:0005515protein binding
0.34GO:0016740transferase activity
0.54GO:0031965nuclear membrane
0.49GO:0005654nucleoplasm
0.36GO:0005576extracellular region
0.33GO:0005737cytoplasm
0.49EC:6 GO:0016874
sp|Q86UX2|ITIH5_HUMAN
Inter-alpha-trypsin inhibitor heavy chain H5
Search
ITIH5
0.96Inter-alpha-trypsin inhibitor heavy chain family member 5
0.84GO:0030212hyaluronan metabolic process
0.75GO:0010951negative regulation of endopeptidase activity
0.34GO:0006953acute-phase response
0.34GO:0034097response to cytokine
0.77GO:0004867serine-type endopeptidase inhibitor activity
0.38GO:0005576extracellular region
0.30GO:0031224intrinsic component of membrane
sp|Q86UX6|ST32C_HUMAN
Serine/threonine-protein kinase 32C
Search
STK32C
0.97Serine/threonine-protein kinase 32C
0.62GO:0006468protein phosphorylation
0.48GO:0018209peptidyl-serine modification
0.41GO:0035556intracellular signal transduction
0.62GO:0004672protein kinase activity
0.54GO:0030554adenyl nucleotide binding
0.53GO:0097367carbohydrate derivative binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.34GO:0046872metal ion binding
0.35GO:0005622intracellular
sp|Q86UX7|URP2_HUMAN
Fermitin family homolog 3
Search
FERMT3
0.94Fermitin family like protein 3
0.80GO:0007229integrin-mediated signaling pathway
0.61GO:0033628regulation of cell adhesion mediated by integrin
0.61GO:0033622integrin activation
0.58GO:0034446substrate adhesion-dependent cell spreading
0.57GO:0070527platelet aggregation
0.57GO:0007159leukocyte cell-cell adhesion
0.53GO:0030335positive regulation of cell migration
0.51GO:0022407regulation of cell-cell adhesion
0.48GO:0051546keratinocyte migration
0.48GO:0051886negative regulation of timing of anagen
0.55GO:0005178integrin binding
0.41GO:0005547phosphatidylinositol-3,4,5-trisphosphate binding
0.57GO:0002102podosome
0.48GO:0031941filamentous actin
0.48GO:0005925focal adhesion
0.42GO:0005829cytosol
0.39GO:0031234extrinsic component of cytoplasmic side of plasma membrane
0.39GO:0097517contractile actin filament bundle
0.39GO:0042641actomyosin
0.39GO:0043233organelle lumen
0.38GO:0042995cell projection
0.38GO:0044428nuclear part
sp|Q86UY5|FA83A_HUMAN
Protein FAM83A
Search
sp|Q86UY6|NAA40_HUMAN
N-alpha-acetyltransferase 40
Search
NAA40
0.94N-alpha-acetyltransferase 40, NatD catalytic subunit
0.56GO:0043968histone H2A acetylation
0.55GO:0043967histone H4 acetylation
0.53GO:0006474N-terminal protein amino acid acetylation
0.45GO:0006629lipid metabolic process
0.34GO:0016579protein deubiquitination
0.33GO:1902600hydrogen ion transmembrane transport
0.33GO:0022900electron transport chain
0.32GO:0043043peptide biosynthetic process
0.31GO:0009059macromolecule biosynthetic process
0.66GO:0008080N-acetyltransferase activity
0.34GO:0004843thiol-dependent ubiquitin-specific protease activity
0.33GO:0005515protein binding
0.33GO:0015002heme-copper terminal oxidase activity
0.33GO:0016676oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33GO:0015078hydrogen ion transmembrane transporter activity
0.33GO:0009055electron transfer activity
0.32GO:0003735structural constituent of ribosome
0.36GO:0005634nucleus
0.34GO:0005737cytoplasm
0.32GO:0030529intracellular ribonucleoprotein complex
0.32GO:0043232intracellular non-membrane-bounded organelle
0.66EC:2.3.1 GO:0008080
sp|Q86UY8|NT5D3_HUMAN
5'-nucleotidase domain-containing protein 3
Search
NT5DC3
0.965'-nucleotidase domain-containing protein 3
0.44GO:0016311dephosphorylation
0.52GO:0046872metal ion binding
0.48GO:00082535'-nucleotidase activity
0.54GO:0043235receptor complex
0.35GO:0005829cytosol
0.34GO:0005739mitochondrion
0.48EC:3.1.3.5 GO:0008253
sp|Q86UZ6|ZBT46_HUMAN
Zinc finger and BTB domain-containing protein 46
Search
ZBTB46
0.97Zinc finger and BTB domain-containing protein 46
0.71GO:2001200positive regulation of dendritic cell differentiation
0.71GO:2001199negative regulation of dendritic cell differentiation
0.70GO:0045650negative regulation of macrophage differentiation
0.69GO:0045656negative regulation of monocyte differentiation
0.69GO:0030853negative regulation of granulocyte differentiation
0.35GO:0006351transcription, DNA-templated
0.35GO:1903506regulation of nucleic acid-templated transcription
0.35GO:2000112regulation of cellular macromolecule biosynthetic process
0.35GO:0010468regulation of gene expression
0.51GO:0003676nucleic acid binding
0.35GO:0046872metal ion binding
0.34GO:0005515protein binding
0.36GO:0005634nucleus
sp|Q86V15|CASZ1_HUMAN
Zinc finger protein castor homolog 1
Search
CASZ1
0.92Zinc finger protein castor like protein 1
0.46GO:0045893positive regulation of transcription, DNA-templated
0.42GO:0045664regulation of neuron differentiation
0.37GO:0006351transcription, DNA-templated
0.51GO:0003676nucleic acid binding
0.30GO:0043167ion binding
0.45GO:0005654nucleoplasm
0.44GO:0005829cytosol
sp|Q86V20|FA35A_HUMAN
Protein FAM35A
Search
0.30GO:0044425membrane part
sp|Q86V21|AACS_HUMAN
Acetoacetyl-CoA synthetase
Search
AACS
0.66Acetoacetyl-CoA synthetase
0.62GO:0006629lipid metabolic process
0.41GO:0034201response to oleic acid
0.41GO:0071394cellular response to testosterone stimulus
0.41GO:0071397cellular response to cholesterol
0.41GO:0050872white fat cell differentiation
0.40GO:0060612adipose tissue development
0.40GO:0032024positive regulation of insulin secretion
0.40GO:0071333cellular response to glucose stimulus
0.40GO:0045471response to ethanol
0.40GO:0001889liver development
0.82GO:0030729acetoacetate-CoA ligase activity
0.41GO:0047760butyrate-CoA ligase activity
0.36GO:0030554adenyl nucleotide binding
0.35GO:0032555purine ribonucleotide binding
0.35GO:0008144drug binding
0.35GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0005515protein binding
0.39GO:0005829cytosol
0.30GO:0016020membrane
0.82EC:6.2.1.16 GO:0030729
0.82KEGG:R01357 GO:0030729
sp|Q86V24|ADR2_HUMAN
Adiponectin receptor protein 2
Search
ADIPOR2
0.97Adiponectin receptor protein 2
0.61GO:0033211adiponectin-activated signaling pathway
0.58GO:0061042vascular wound healing
0.53GO:0042593glucose homeostasis
0.41GO:0046326positive regulation of glucose import
0.40GO:0007565female pregnancy
0.40GO:0030308negative regulation of cell growth
0.40GO:0007584response to nutrient
0.39GO:0007507heart development
0.37GO:0019395fatty acid oxidation
0.36GO:0019216regulation of lipid metabolic process
0.60GO:0097003adipokinetic hormone receptor activity
0.60GO:0055100adiponectin binding
0.50GO:0046982protein heterodimerization activity
0.50GO:0042802identical protein binding
0.34GO:0019901protein kinase binding
0.33GO:0046872metal ion binding
0.47GO:0031226intrinsic component of plasma membrane
0.30GO:0016021integral component of membrane
sp|Q86V25|VASH2_HUMAN
Vasohibin-2
Search
VASH2
0.96Testicular tissue protein Li 222
0.82GO:0045765regulation of angiogenesis
0.65GO:0001936regulation of endothelial cell proliferation
0.62GO:0060716labyrinthine layer blood vessel development
0.58GO:0000768syncytium formation by plasma membrane fusion
0.57GO:0045026plasma membrane fusion
0.56GO:1904018positive regulation of vasculature development
0.56GO:0050679positive regulation of epithelial cell proliferation
0.53GO:0050680negative regulation of epithelial cell proliferation
0.53GO:2000181negative regulation of blood vessel morphogenesis
0.52GO:1901491negative regulation of lymphangiogenesis
0.33GO:0005515protein binding
0.49GO:0005737cytoplasm
0.47GO:0045177apical part of cell
0.44GO:0005615extracellular space
0.43GO:0012505endomembrane system
0.39GO:0043231intracellular membrane-bounded organelle
0.30GO:0016020membrane
sp|Q86V35|CABP7_HUMAN
Calcium-binding protein 7
Search
CABP7
0.97Calcium binding protein 7
0.70GO:0005509calcium ion binding
0.64GO:0032588trans-Golgi network membrane
0.42GO:0048471perinuclear region of cytoplasm
0.37GO:0005689U12-type spliceosomal complex
0.36GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q86V40|TIKI1_HUMAN
Metalloprotease TIKI1
Search
0.96TraB domain containing 2A
0.80GO:0030178negative regulation of Wnt signaling pathway
0.68GO:1904808positive regulation of protein oxidation
0.63GO:0032461positive regulation of protein oligomerization
0.59GO:0006508proteolysis
0.84GO:0017147Wnt-protein binding
0.68GO:0004222metalloendopeptidase activity
0.74GO:0031301integral component of organelle membrane
0.65GO:0005887integral component of plasma membrane
0.40GO:0070062extracellular exosome
0.68EC:3.4.24 GO:0004222
sp|Q86V42|F124A_HUMAN
Protein FAM124A
Search
0.39GO:0006182cGMP biosynthetic process
0.36GO:0035556intracellular signal transduction
0.44GO:0005515protein binding
0.39GO:0004383guanylate cyclase activity
0.36GO:0020037heme binding
0.34GO:1901265nucleoside phosphate binding
0.34GO:0036094small molecule binding
0.60GO:0005654nucleoplasm
0.53GO:0005739mitochondrion
0.45GO:0005615extracellular space
0.30GO:0031224intrinsic component of membrane
0.39EC:4.6.1.2 GO:0004383
sp|Q86V48|LUZP1_HUMAN
Leucine zipper protein 1
Search
LUZP1
0.97Leucine zipper protein 1
0.88GO:0021503neural fold bending
0.85GO:0003281ventricular septum development
0.85GO:0060840artery development
0.61GO:0005634nucleus
0.46GO:0070062extracellular exosome
0.30GO:0031224intrinsic component of membrane
sp|Q86V59|PNML1_HUMAN
PNMA-like protein 1
Search
PNMA8A
0.97Paraneoplastic Ma antigen family member 8A
0.53GO:0002437inflammatory response to antigenic stimulus
0.42GO:0043065positive regulation of apoptotic process
0.38GO:0005515protein binding
0.70GO:0005730nucleolus
0.46GO:0005737cytoplasm
sp|Q86V71|ZN429_HUMAN
Zinc finger protein 429
Search
0.72Zinc finger protein 85
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.57GO:1903506regulation of nucleic acid-templated transcription
0.56GO:0010468regulation of gene expression
0.38GO:0097659nucleic acid-templated transcription
0.37GO:0010467gene expression
0.37GO:0034645cellular macromolecule biosynthetic process
0.53GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.45GO:0005622intracellular
0.38GO:0043227membrane-bounded organelle
sp|Q86V81|THOC4_HUMAN
THO complex subunit 4
Search
ALYREF
0.91RNA and export factor binding protein 2
0.41GO:0051028mRNA transport
0.40GO:0008380RNA splicing
0.39GO:0006397mRNA processing
0.37GO:0046784viral mRNA export from host cell nucleus
0.37GO:0050790regulation of catalytic activity
0.37GO:0001649osteoblast differentiation
0.37GO:0031297replication fork processing
0.36GO:0032786positive regulation of DNA-templated transcription, elongation
0.36GO:0071427mRNA-containing ribonucleoprotein complex export from nucleus
0.36GO:0000018regulation of DNA recombination
0.59GO:0003723RNA binding
0.40GO:0005094Rho GDP-dissociation inhibitor activity
0.37GO:0004306ethanolamine-phosphate cytidylyltransferase activity
0.36GO:0003697single-stranded DNA binding
0.35GO:0070403NAD+ binding
0.33GO:0005515protein binding
0.32GO:0016853isomerase activity
0.50GO:0016607nuclear speck
0.39GO:0005681spliceosomal complex
0.37GO:0035145exon-exon junction complex
0.37GO:0000346transcription export complex
0.36GO:0000784nuclear chromosome, telomeric region
0.36GO:0070062extracellular exosome
0.36GO:0005737cytoplasm
0.34GO:1902494catalytic complex
0.30GO:0016020membrane
0.37EC:2.7.7.14 GO:0004306
sp|Q86V85|GP180_HUMAN
Integral membrane protein GPR180
Search
GPR180
0.88G protein-coupled receptor 180
0.82GO:0019236response to pheromone
0.71GO:0007186G-protein coupled receptor signaling pathway
0.39GO:0070062extracellular exosome
0.30GO:0044425membrane part
sp|Q86V86|PIM3_HUMAN
Serine/threonine-protein kinase pim-3
Search
PIM3
0.93Proto-oncogene serine/threonine-protein kinase pim-1
0.77GO:0043066negative regulation of apoptotic process
0.63GO:0006468protein phosphorylation
0.51GO:1905062positive regulation of cardioblast proliferation
0.51GO:0007346regulation of mitotic cell cycle
0.50GO:0070561vitamin D receptor signaling pathway
0.50GO:0061179negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.49GO:0060045positive regulation of cardiac muscle cell proliferation
0.47GO:0043433negative regulation of DNA binding transcription factor activity
0.46GO:0008283cell proliferation
0.41GO:0006915apoptotic process
0.69GO:0004674protein serine/threonine kinase activity
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.49GO:0043024ribosomal small subunit binding
0.44GO:0008134transcription factor binding
0.44GO:0030145manganese ion binding
0.33GO:0005509calcium ion binding
0.49GO:0005829cytosol
0.44GO:0005730nucleolus
0.33GO:0005886plasma membrane
0.33GO:0005654nucleoplasm
0.30GO:0031224intrinsic component of membrane
0.69EC:2.7.11 GO:0004674
sp|Q86V87|F16B2_HUMAN
Protein FAM160B2
Search
0.93Retinoic acid induced 16
sp|Q86V88|MGDP1_HUMAN
Magnesium-dependent phosphatase 1
Search
MDP1
0.43Magnesium-dependent phosphatase
0.68GO:0016311dephosphorylation
0.41GO:0030389fructosamine metabolic process
0.39GO:0007034vacuolar transport
0.35GO:0006464cellular protein modification process
0.32GO:0055114oxidation-reduction process
0.69GO:0016791phosphatase activity
0.34GO:0140096catalytic activity, acting on a protein
0.34GO:0046872metal ion binding
0.32GO:0016627oxidoreductase activity, acting on the CH-CH group of donors
0.32GO:0003676nucleic acid binding
0.38GO:0070062extracellular exosome
0.69EC:3.1.3 EC:3.1.3.41 GO:0016791
sp|Q86V97|KBTB6_HUMAN
Kelch repeat and BTB domain-containing protein 6
Search
KBTBD7
0.97LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 6
0.73GO:0016567protein ubiquitination
0.48GO:0043687post-translational protein modification
0.42GO:0000165MAPK cascade
0.32GO:2001141regulation of RNA biosynthetic process
0.32GO:2000112regulation of cellular macromolecule biosynthetic process
0.32GO:0010468regulation of gene expression
0.73GO:0004842ubiquitin-protein transferase activity
0.42GO:0005515protein binding
0.32GO:0043565sequence-specific DNA binding
0.32GO:0003700DNA binding transcription factor activity
0.83GO:0031463Cul3-RING ubiquitin ligase complex
0.44GO:0005829cytosol
0.32GO:0005634nucleus
0.73KEGG:R03876 GO:0004842
sp|Q86VB7|C163A_HUMAN
Scavenger receptor cysteine-rich type 1 protein M130
Search
0.10Scavenger receptor cysteine-rich type 1 protein M130
0.72GO:0006898receptor-mediated endocytosis
0.30GO:0006950response to stress
0.81GO:0005044scavenger receptor activity
0.30GO:0005488binding
0.47GO:0009897external side of plasma membrane
0.30GO:0044422organelle part
0.30GO:0005737cytoplasm
0.30GO:0005576extracellular region
0.30GO:0098805whole membrane
0.30GO:0031982vesicle
0.30GO:0031226intrinsic component of plasma membrane
0.30GO:0016021integral component of membrane
0.30GO:0043229intracellular organelle
sp|Q86VD1|MORC1_HUMAN
MORC family CW-type zinc finger protein 1
Search
MORC1
0.90MORC family CW-type zinc finger protein 1
0.60GO:0044026DNA hypermethylation
0.59GO:2000143negative regulation of DNA-templated transcription, initiation
0.58GO:0043046DNA methylation involved in gamete generation
0.58GO:0010529negative regulation of transposition
0.54GO:0007283spermatogenesis
0.53GO:0040029regulation of gene expression, epigenetic
0.37GO:0030154cell differentiation
0.37GO:0007275multicellular organism development
0.33GO:0006631fatty acid metabolic process
0.33GO:0055114oxidation-reduction process
0.62GO:0008270zinc ion binding
0.33GO:0016491oxidoreductase activity
0.49GO:0005634nucleus
0.43GO:0005829cytosol
0.30GO:0016020membrane
0.33EC:1 GO:0016491
sp|Q86VD7|S2542_HUMAN
Mitochondrial coenzyme A transporter SLC25A42
Search
SLC25A42
0.95Mitochondrial coenzyme A transporter SLC25A42
0.60GO:0080121AMP transport
0.59GO:0071106adenosine 3',5'-bisphosphate transmembrane transport
0.59GO:0015880coenzyme A transport
0.57GO:0015866ADP transport
0.55GO:0015867ATP transport
0.49GO:0098656anion transmembrane transport
0.48GO:0006839mitochondrial transport
0.35GO:0050829defense response to Gram-negative bacterium
0.35GO:0045089positive regulation of innate immune response
0.34GO:0007006mitochondrial membrane organization
0.60GO:0080122AMP transmembrane transporter activity
0.59GO:0071077adenosine 3',5'-bisphosphate transmembrane transporter activity
0.59GO:0043262adenosine-diphosphatase activity
0.57GO:0015217ADP transmembrane transporter activity
0.55GO:0005347ATP transmembrane transporter activity
0.54GO:0051185coenzyme transmembrane transporter activity
0.36GO:0015297antiporter activity
0.57GO:0031966mitochondrial membrane
0.57GO:0019866organelle inner membrane
0.34GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
sp|Q86VD9|PIGZ_HUMAN
GPI mannosyltransferase 4
Search
PIGZ
0.53Mannosyltransferase
0.61GO:0006506GPI anchor biosynthetic process
0.61GO:0097502mannosylation
0.33GO:0006276plasmid maintenance
0.65GO:0016757transferase activity, transferring glycosyl groups
0.32GO:0070403NAD+ binding
0.72GO:0005789endoplasmic reticulum membrane
0.30GO:0031224intrinsic component of membrane
0.65EC:2.4 GO:0016757
sp|Q86VE0|MYPOP_HUMAN
Myb-related transcription factor, partner of profilin
Search
MYPOP
0.97Myb-related transcription factor, partner of profilin
0.78GO:0000122negative regulation of transcription by RNA polymerase II
0.40GO:0006351transcription, DNA-templated
0.84GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.80GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
0.75GO:0042803protein homodimerization activity
0.61GO:0005634nucleus
sp|Q86VE3|SATL1_HUMAN
Spermidine/spermine N(1)-acetyltransferase-like protein 1
Search
SATL1
0.88Spermidine/spermine N1-acetyl transferase like 1
0.55GO:0032918spermidine acetylation
0.55GO:0046208spermine catabolic process
0.51GO:0001525angiogenesis
0.47GO:0042127regulation of cell proliferation
0.42GO:0009447putrescine catabolic process
0.37GO:0032919spermine acetylation
0.34GO:0006596polyamine biosynthetic process
0.80GO:0004145diamine N-acetyltransferase activity
0.56GO:0019809spermidine binding
0.48GO:0042802identical protein binding
0.45GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
0.80EC:2.3.1.57 GO:0004145
sp|Q86VE9|SERC5_HUMAN
Serine incorporator 5
Search
SERINC5
0.97Serine incorporator 5
0.80GO:0006658phosphatidylserine metabolic process
0.80GO:0042552myelination
0.75GO:0006665sphingolipid metabolic process
0.57GO:0009597detection of virus
0.51GO:0045087innate immune response
0.51GO:0051607defense response to virus
0.50GO:0015825L-serine transport
0.40GO:1904219positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.40GO:1904222positive regulation of serine C-palmitoyltransferase activity
0.37GO:0008654phospholipid biosynthetic process
0.51GO:0015194L-serine transmembrane transporter activity
0.34GO:0030674protein binding, bridging
0.34GO:00515372 iron, 2 sulfur cluster binding
0.53GO:0043209myelin sheath
0.48GO:0005794Golgi apparatus
0.41GO:0005886plasma membrane
0.36GO:0070062extracellular exosome
0.35GO:0048471perinuclear region of cytoplasm
0.30GO:0016021integral component of membrane
sp|Q86VF2|IGFN1_HUMAN
Immunoglobulin-like and fibronectin type III domain-containing protein 1
Search
IGFN1
0.82Immunoglobulin-like and fibronectin type III domain-containing protein 1
0.56GO:0006468protein phosphorylation
0.40GO:0071688striated muscle myosin thick filament assembly
0.40GO:0098609cell-cell adhesion
0.39GO:0045214sarcomere organization
0.39GO:0006941striated muscle contraction
0.38GO:0048010vascular endothelial growth factor receptor signaling pathway
0.38GO:0038084vascular endothelial growth factor signaling pathway
0.37GO:0007015actin filament organization
0.37GO:0018212peptidyl-tyrosine modification
0.36GO:1905563negative regulation of vascular endothelial cell proliferation
0.57GO:0004672protein kinase activity
0.50GO:0030554adenyl nucleotide binding
0.49GO:0097367carbohydrate derivative binding
0.49GO:0008144drug binding
0.49GO:0035639purine ribonucleoside triphosphate binding
0.46GO:0005515protein binding
0.40GO:0097493structural molecule activity conferring elasticity
0.39GO:0008307structural constituent of muscle
0.37GO:0044877macromolecular complex binding
0.36GO:0004888transmembrane signaling receptor activity
0.56GO:0030018Z disc
0.46GO:0005634nucleus
0.41GO:0030057desmosome
0.40GO:0005859muscle myosin complex
0.39GO:0031430M band
0.35GO:0005887integral component of plasma membrane
0.35GO:0043235receptor complex
0.34GO:0030673axolemma
0.33GO:0005768endosome
0.33GO:0005576extracellular region
sp|Q86VF5|MOGT3_HUMAN
2-acylglycerol O-acyltransferase 3
Search
MOGAT3
0.88Monoacylglycerol O-acyltransferase 3
0.46GO:0046463acylglycerol biosynthetic process
0.45GO:0046339diacylglycerol metabolic process
0.43GO:0006641triglyceride metabolic process
0.39GO:0050892intestinal absorption
0.39GO:0006071glycerol metabolic process
0.36GO:0071400cellular response to oleic acid
0.36GO:0060613fat pad development
0.36GO:0035356cellular triglyceride homeostasis
0.36GO:0034383low-density lipoprotein particle clearance
0.36GO:1901568fatty acid derivative metabolic process
0.64GO:0016747transferase activity, transferring acyl groups other than amino-acyl groups
0.35GO:0042803protein homodimerization activity
0.42GO:0005783endoplasmic reticulum
0.39GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.39GO:0031984organelle subcompartment
0.37GO:0005811lipid droplet
0.35GO:0048471perinuclear region of cytoplasm
0.33GO:0005739mitochondrion
0.30GO:0016021integral component of membrane
0.64EC:2.3.1 GO:0016747
sp|Q86VF7|NRAP_HUMAN
Nebulin-related-anchoring protein
Search
NRAP
0.66nebulin-related-anchoring protein isoform X1
0.34GO:0030036actin cytoskeleton organization
0.73GO:0003779actin binding
0.57GO:0051371muscle alpha-actinin binding
0.57GO:0017166vinculin binding
0.52GO:0046872metal ion binding
0.33GO:0032550purine ribonucleoside binding
0.33GO:0019001guanyl nucleotide binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0032555purine ribonucleotide binding
0.58GO:0005916fascia adherens
0.57GO:0005927muscle tendon junction
0.53GO:0030016myofibril
0.34GO:0044449contractile fiber part
sp|Q86VG3|CK074_HUMAN
Uncharacterized protein C11orf74
Search
sp|Q86VH2|KIF27_HUMAN
Kinesin-like protein KIF27
Search
KIF27
0.93Kinesin family member 7
0.74GO:0007018microtubule-based movement
0.33GO:0045880positive regulation of smoothened signaling pathway
0.33GO:0045879negative regulation of smoothened signaling pathway
0.33GO:0060976coronary vasculature development
0.33GO:0035904aorta development
0.33GO:0003279cardiac septum development
0.75GO:0003777microtubule motor activity
0.74GO:0008017microtubule binding
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.48GO:0042623ATPase activity, coupled
0.33GO:0042802identical protein binding
0.58GO:0005871kinesin complex
0.44GO:0005929cilium
0.33GO:0120038plasma membrane bounded cell projection part
0.33GO:0005815microtubule organizing center
sp|Q86VH4|LRRT4_HUMAN
Leucine-rich repeat transmembrane neuronal protein 4
Search
LRRTM4
0.96Leucine-rich repeat transmembrane neuronal protein 4
0.47GO:0046426negative regulation of JAK-STAT cascade
0.45GO:0006469negative regulation of protein kinase activity
0.45GO:0019221cytokine-mediated signaling pathway
0.39GO:0050808synapse organization
0.38GO:1901629regulation of presynaptic membrane organization
0.37GO:0043113receptor clustering
0.37GO:0051965positive regulation of synapse assembly
0.35GO:0061024membrane organization
0.46GO:0004860protein kinase inhibitor activity
0.37GO:0043395heparan sulfate proteoglycan binding
0.37GO:0045211postsynaptic membrane
0.37GO:0032281AMPA glutamate receptor complex
0.37GO:0030054cell junction
0.36GO:0005737cytoplasm
sp|Q86VH5|LRRT3_HUMAN
Leucine-rich repeat transmembrane neuronal protein 3
Search
LRRTM3
0.97Leucine-rich repeat transmembrane neuronal protein 3
0.58GO:1902004positive regulation of amyloid-beta formation
0.52GO:0051965positive regulation of synapse assembly
0.50GO:0046426negative regulation of JAK-STAT cascade
0.48GO:0006469negative regulation of protein kinase activity
0.47GO:0019221cytokine-mediated signaling pathway
0.36GO:1901629regulation of presynaptic membrane organization
0.36GO:0097113AMPA glutamate receptor clustering
0.49GO:0004860protein kinase inhibitor activity
0.36GO:0043395heparan sulfate proteoglycan binding
0.40GO:0045211postsynaptic membrane
0.39GO:0030054cell junction
0.37GO:0005737cytoplasm
0.36GO:0032281AMPA glutamate receptor complex
sp|Q86VI1|EX3L1_HUMAN
Exocyst complex component 3-like protein
Search
EXOC3L1
0.92Exocyst complex component 3 like 1
0.77GO:0006887exocytosis
0.69GO:0030072peptide hormone secretion
0.55GO:0051601exocyst localization
0.32GO:0006508proteolysis
0.52GO:0000149SNARE binding
0.32GO:0004252serine-type endopeptidase activity
0.79GO:0000145exocyst
0.65GO:0030141secretory granule
0.41GO:0030133transport vesicle
0.32EC:3.4.21 GO:0004252
sp|Q86VI3|IQGA3_HUMAN
Ras GTPase-activating-like protein IQGAP3
Search
IQGAP3
0.91IQ motif containing GTPase activating protein 3
0.75GO:0043087regulation of GTPase activity
0.65GO:0071902positive regulation of protein serine/threonine kinase activity
0.63GO:0033601positive regulation of mammary gland epithelial cell proliferation
0.62GO:0070371ERK1 and ERK2 cascade
0.60GO:0071310cellular response to organic substance
0.59GO:0000082G1/S transition of mitotic cell cycle
0.58GO:0007265Ras protein signal transduction
0.58GO:0008361regulation of cell size
0.57GO:0043405regulation of MAP kinase activity
0.57GO:0043410positive regulation of MAPK cascade
0.65GO:0070856myosin VI light chain binding
0.64GO:0005516calmodulin binding
0.60GO:0017048Rho GTPase binding
0.56GO:0044548S100 protein binding
0.56GO:0005547phosphatidylinositol-3,4,5-trisphosphate binding
0.55GO:0043539protein serine/threonine kinase activator activity
0.54GO:0019903protein phosphatase binding
0.53GO:0045296cadherin binding
0.52GO:0019901protein kinase binding
0.51GO:0019904protein domain specific binding
0.66GO:0016328lateral plasma membrane
0.60GO:0005911cell-cell junction
0.54GO:0001726ruffle
0.54GO:0030496midbody
0.52GO:0031234extrinsic component of cytoplasmic side of plasma membrane
0.52GO:0036464cytoplasmic ribonucleoprotein granule
0.49GO:0005874microtubule
0.49GO:0043005neuron projection
0.44GO:0005634nucleus
0.44GO:0030427site of polarized growth
sp|Q86VI4|LAP4B_HUMAN
Lysosomal-associated transmembrane protein 4B
Search
LAPTM4B
0.96Lysosomal associated protein transmembrane 4 beta
0.61GO:1905671regulation of lysosome organization
0.61GO:1905166negative regulation of lysosomal protein catabolic process
0.61GO:0097213regulation of lysosomal membrane permeability
0.60GO:0032911negative regulation of transforming growth factor beta1 production
0.56GO:0007032endosome organization
0.55GO:0032509endosome transport via multivesicular body sorting pathway
0.59GO:0097001ceramide binding
0.55GO:1902936phosphatidylinositol bisphosphate binding
0.54GO:0031625ubiquitin protein ligase binding
0.53GO:0019900kinase binding
0.60GO:0097487multivesicular body, internal vesicle
0.59GO:0032585multivesicular body membrane
0.55GO:0005765lysosomal membrane
0.54GO:0005769early endosome
0.48GO:0042995cell projection
0.42GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q86VK4|ZN410_HUMAN
Zinc finger protein 410
Search
ZNF410
0.97Zinc finger protein 410
0.35GO:0006351transcription, DNA-templated
0.34GO:2001141regulation of RNA biosynthetic process
0.34GO:2000112regulation of cellular macromolecule biosynthetic process
0.34GO:0010468regulation of gene expression
0.34GO:0006744ubiquinone biosynthetic process
0.32GO:0055114oxidation-reduction process
0.51GO:0003676nucleic acid binding
0.34GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.34GO:0046872metal ion binding
0.34GO:0016709oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.34GO:0071949FAD binding
0.33GO:0005515protein binding
0.35GO:0005634nucleus
0.34GO:0031314extrinsic component of mitochondrial inner membrane
0.34GO:0005794Golgi apparatus
0.33GO:0042995cell projection
0.30GO:0031224intrinsic component of membrane
0.34EC:1.14.14 GO:0016712
sp|Q86VL8|S47A2_HUMAN
Multidrug and toxin extrusion protein 2
Search
SLC47A2
0.74Multidrug and toxin extrusion protein 2
0.72GO:0006855drug transmembrane transport
0.41GO:0046618drug export
0.34GO:0055114oxidation-reduction process
0.72GO:0015238drug transmembrane transporter activity
0.72GO:0015297antiporter activity
0.37GO:0015078hydrogen ion transmembrane transporter activity
0.36GO:0016620oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33GO:0001883purine nucleoside binding
0.33GO:0019001guanyl nucleotide binding
0.33GO:0032549ribonucleoside binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0032555purine ribonucleotide binding
0.36GO:0005886plasma membrane
0.30GO:0044425membrane part
0.36EC:1.2.1 GO:0016620
sp|Q86VM9|ZCH18_HUMAN
Zinc finger CCCH domain-containing protein 18
Search
ZC3H18
0.93Zinc finger CCCH domain-containing protein 18
0.34GO:0006954inflammatory response
0.34GO:0010469regulation of receptor activity
0.52GO:0046872metal ion binding
0.35GO:0003723RNA binding
0.35GO:0005515protein binding
0.34GO:0030545receptor regulator activity
0.54GO:0016607nuclear speck
0.36GO:0043234protein complex
0.33GO:0005576extracellular region
0.30GO:0044425membrane part
sp|Q86VN1|VPS36_HUMAN
Vacuolar protein-sorting-associated protein 36
Search
VPS36
0.91Vacuolar protein-sorting-associated protein 36
0.78GO:0032509endosome transport via multivesicular body sorting pathway
0.48GO:0043162ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.48GO:0045324late endosome to vacuole transport
0.47GO:0072666establishment of protein localization to vacuole
0.43GO:0006886intracellular protein transport
0.36GO:0036258multivesicular body assembly
0.35GO:0006351transcription, DNA-templated
0.35GO:2001141regulation of RNA biosynthetic process
0.35GO:2000112regulation of cellular macromolecule biosynthetic process
0.35GO:0010468regulation of gene expression
0.79GO:0032266phosphatidylinositol-3-phosphate binding
0.78GO:0043130ubiquitin binding
0.55GO:0008022protein C-terminus binding
0.35GO:0003730mRNA 3'-UTR binding
0.79GO:0000814ESCRT II complex
0.57GO:0031902late endosome membrane
0.53GO:0005764lysosome
0.48GO:0005829cytosol
0.37GO:0070062extracellular exosome
0.36GO:0005634nucleus
sp|Q86VP1|TAXB1_HUMAN
Tax1-binding protein 1
Search
TAX1BP1
0.93Muscle-derived protein 62
0.83GO:0032088negative regulation of NF-kappaB transcription factor activity
0.52GO:0006915apoptotic process
0.46GO:0043066negative regulation of apoptotic process
0.43GO:0032480negative regulation of type I interferon production
0.43GO:0010803regulation of tumor necrosis factor-mediated signaling pathway
0.38GO:0010976positive regulation of neuron projection development
0.33GO:0006811ion transport
0.76GO:0019900kinase binding
0.41GO:0046872metal ion binding
0.39GO:0043130ubiquitin binding
0.44GO:0070062extracellular exosome
0.38GO:0005829cytosol
0.36GO:0005783endoplasmic reticulum
0.30GO:0016020membrane
sp|Q86VP3|PACS2_HUMAN
Phosphofurin acidic cluster sorting protein 2
Search
PACS2
0.94Phosphofurin acidic cluster sorting protein 2
0.82GO:0034497protein localization to phagophore assembly site
0.78GO:0072659protein localization to plasma membrane
0.43GO:0006915apoptotic process
0.37GO:0016032viral process
0.66GO:0044325ion channel binding
0.67GO:0005783endoplasmic reticulum
0.58GO:0005739mitochondrion
0.30GO:0031224intrinsic component of membrane
sp|Q86VP6|CAND1_HUMAN
Cullin-associated NEDD8-dissociated protein 1
Search
CAND1
0.79Cullin-associated and neddylation-dissociated protein 1
0.86GO:0010265SCF complex assembly
0.70GO:0016567protein ubiquitination
0.64GO:0043086negative regulation of catalytic activity
0.64GO:0030154cell differentiation
0.58GO:0045899positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.47GO:0043312neutrophil degranulation
0.45GO:0043687post-translational protein modification
0.44GO:0006879cellular iron ion homeostasis
0.40GO:0010467gene expression
0.39GO:0009059macromolecule biosynthetic process
0.56GO:0017025TBP-class protein binding
0.40GO:0003735structural constituent of ribosome
0.71GO:0031461cullin-RING ubiquitin ligase complex
0.65GO:0005794Golgi apparatus
0.63GO:0005654nucleoplasm
0.62GO:0005829cytosol
0.51GO:0070062extracellular exosome
0.48GO:1904813ficolin-1-rich granule lumen
0.47GO:0034774secretory granule lumen
0.39GO:0005840ribosome
0.30GO:0016020membrane
sp|Q86VQ0|LCA5_HUMAN
Lebercilin
Search
LCA5
0.95Leber congenital amaurosis 5
0.44GO:0045494photoreceptor cell maintenance
0.43GO:0042073intraciliary transport
0.75GO:0032403protein complex binding
0.35GO:0031492nucleosomal DNA binding
0.76GO:0005929cilium
0.45GO:0005815microtubule organizing center
0.42GO:0032838plasma membrane bounded cell projection cytoplasm
0.34GO:0000785chromatin
0.33GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
sp|Q86VQ1|GLCI1_HUMAN
Glucocorticoid-induced transcript 1 protein
Search
GLCCI1
0.96Glucocorticoid-induced transcript 1 protein isoform B
0.55GO:0005515protein binding
0.49GO:0005737cytoplasm
sp|Q86VQ3|TXND2_HUMAN
Thioredoxin domain-containing protein 2
Search
TXNDC2
0.94LOW QUALITY PROTEIN: thioredoxin domain-containing protein 2
0.76GO:0006662glycerol ether metabolic process
0.69GO:0045454cell redox homeostasis
0.55GO:0098869cellular oxidant detoxification
0.53GO:0055114oxidation-reduction process
0.52GO:0034599cellular response to oxidative stress
0.46GO:0007283spermatogenesis
0.44GO:0030154cell differentiation
0.43GO:0007275multicellular organism development
0.42GO:0046826negative regulation of protein export from nucleus
0.42GO:0033158regulation of protein import into nucleus, translocation
0.72GO:0015035protein disulfide oxidoreductase activity
0.61GO:0004791thioredoxin-disulfide reductase activity
0.55GO:0047134protein-disulfide reductase activity
0.52GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.40GO:0015037peptide disulfide oxidoreductase activity
0.39GO:0003756protein disulfide isomerase activity
0.35GO:0005515protein binding
0.33GO:0003723RNA binding
0.42GO:0005737cytoplasm
0.40GO:0036126sperm flagellum
0.37GO:0120038plasma membrane bounded cell projection part
0.36GO:0005634nucleus
0.35GO:0099513polymeric cytoskeletal fiber
0.35GO:0005576extracellular region
0.35GO:0043025neuronal cell body
0.35GO:0097447dendritic tree
0.35GO:0030424axon
0.34GO:0031982vesicle
0.61EC:1.8.1.9 GO:0004791
0.61KEGG:R02016 GO:0004791
sp|Q86VQ6|TRXR3_HUMAN
Thioredoxin reductase 3
Search
TXNRD3
0.91Thioredoxin reductase 1, cytoplasmic
0.67GO:0098869cellular oxidant detoxification
0.67GO:0045454cell redox homeostasis
0.59GO:0022900electron transport chain
0.47GO:0001707mesoderm formation
0.46GO:0008283cell proliferation
0.45GO:0000305response to oxygen radical
0.37GO:0006749glutathione metabolic process
0.37GO:0007283spermatogenesis
0.36GO:0030154cell differentiation
0.36GO:0070276halogen metabolic process
0.77GO:0004791thioredoxin-disulfide reductase activity
0.64GO:0050660flavin adenine dinucleotide binding
0.60GO:0015035protein disulfide oxidoreductase activity
0.60GO:0009055electron transfer activity
0.36GO:0098626methylseleninic acid reductase activity
0.36GO:0098625methylselenol reductase activity
0.36GO:0098623selenite reductase activity
0.35GO:0033797selenate reductase activity
0.35GO:0005515protein binding
0.35GO:0016174NAD(P)H oxidase activity
0.53GO:0005654nucleoplasm
0.52GO:0005829cytosol
0.49GO:0001650fibrillar center
0.43GO:0005739mitochondrion
0.36GO:0070062extracellular exosome
0.36GO:0005783endoplasmic reticulum
0.34GO:0043025neuronal cell body
0.31GO:0005840ribosome
0.30GO:0031224intrinsic component of membrane
0.77EC:1.8.1.9 GO:0004791
0.77KEGG:R02016 GO:0004791
sp|Q86VR2|F134C_HUMAN
Protein FAM134C
Search
RETREG3
0.97Reticulophagy regulator 3
0.82GO:0010976positive regulation of neuron projection development
0.44GO:0061709reticulophagy
0.39GO:0019233sensory perception of pain
0.39GO:0043524negative regulation of neuron apoptotic process
0.36GO:0005515protein binding
0.41GO:0030176integral component of endoplasmic reticulum membrane
0.38GO:0005801cis-Golgi network
0.38GO:0016604nuclear body
0.37GO:0005730nucleolus
sp|Q86VR7|VS10L_HUMAN
V-set and immunoglobulin domain-containing protein 10-like
Search
VSIG10L
0.97V-set and immunoglobulin domain containing 10 like
0.36GO:0022900electron transport chain
0.33GO:0019991septate junction assembly
0.36GO:0009055electron transfer activity
0.59GO:0005654nucleoplasm
0.33GO:0005918septate junction
0.30GO:0031224intrinsic component of membrane
sp|Q86VR8|FJX1_HUMAN
Four-jointed box protein 1
Search
FJX1
0.97Four-jointed box protein 1
0.85GO:0010842retina layer formation
0.62GO:0007267cell-cell signaling
0.73GO:0005615extracellular space
sp|Q86VS3|IQCH_HUMAN
IQ domain-containing protein H
Search
IQCH
0.97IQ domain-containing protein H
0.47GO:0043043peptide biosynthetic process
0.45GO:0044267cellular protein metabolic process
0.44GO:0010467gene expression
0.43GO:0009059macromolecule biosynthetic process
0.50GO:0003735structural constituent of ribosome
0.48GO:0005840ribosome
sp|Q86VS8|HOOK3_HUMAN
Protein Hook homolog 3
Search
HOOK3
0.94Hook microtubule tethering protein 3
0.85GO:0022027interkinetic nuclear migration
0.85GO:0051645Golgi localization
0.84GO:0045022early endosome to late endosome transport
0.84GO:0097150neuronal stem cell population maintenance
0.83GO:0034454microtubule anchoring at centrosome
0.83GO:0071539protein localization to centrosome
0.83GO:0008333endosome to lysosome transport
0.82GO:0031122cytoplasmic microtubule organization
0.81GO:0007032endosome organization
0.81GO:0007040lysosome organization
0.73GO:0008017microtubule binding
0.70GO:0042802identical protein binding
0.63GO:0051959dynein light intermediate chain binding
0.48GO:0008318protein prenyltransferase activity
0.36GO:0004672protein kinase activity
0.35GO:0032559adenyl ribonucleotide binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.85GO:0070695FHF complex
0.84GO:0000242pericentriolar material
0.83GO:0034451centriolar satellite
0.83GO:0030897HOPS complex
0.78GO:0005801cis-Golgi network
0.66GO:0005829cytosol
0.44GO:0005874microtubule
0.43GO:0005794Golgi apparatus
0.48EC:2.5.1 GO:0008318
sp|Q86VU5|CMTD1_HUMAN
Catechol O-methyltransferase domain-containing protein 1
Search
COMTD1
0.38Predicted O-methyltransferase YrrM
0.63GO:0032259methylation
0.73GO:0008171O-methyltransferase activity
0.34GO:0008757S-adenosylmethionine-dependent methyltransferase activity
0.34GO:0005515protein binding
0.45GO:0005739mitochondrion
0.30GO:0031224intrinsic component of membrane
0.73EC:2.1.1 GO:0008171
sp|Q86VV4|RNB3L_HUMAN
Ran-binding protein 3-like
Search
RANBP3L
0.81Ran-binding protein 3-like
0.69GO:0046907intracellular transport
0.51GO:0046604positive regulation of mitotic centrosome separation
0.48GO:0000082G1/S transition of mitotic cell cycle
0.47GO:0006606protein import into nucleus
0.47GO:0007051spindle organization
0.47GO:1901706mesenchymal cell differentiation involved in bone development
0.46GO:0043547positive regulation of GTPase activity
0.45GO:0006405RNA export from nucleus
0.45GO:0006511ubiquitin-dependent protein catabolic process
0.44GO:0045663positive regulation of myoblast differentiation
0.47GO:0008536Ran GTPase binding
0.46GO:0005096GTPase activator activity
0.45GO:0046332SMAD binding
0.40GO:0003951NAD+ kinase activity
0.33GO:0003677DNA binding
0.46GO:0005813centrosome
0.41GO:0005634nucleus
0.37GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
0.40EC:2.7.1.23 GO:0003951
0.40KEGG:R00104 GO:0003951
sp|Q86VV8|RTTN_HUMAN
Rotatin
Search
RTTN
0.97Rotatin
0.79GO:0044782cilium organization
0.59GO:0007368determination of left/right symmetry
0.34GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
0.35GO:0033897ribonuclease T2 activity
0.33GO:0003723RNA binding
0.83GO:0036064ciliary basal body
0.78GO:0005813centrosome
0.34GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
0.35EC:3.1.27.1 GO:0033897
sp|Q86VW0|SESD1_HUMAN
SEC14 domain and spectrin repeat-containing protein 1
Search
SESTD1
0.97LOW QUALITY PROTEIN: SEC14 domain and spectrin repeat-containing protein 1
0.86GO:1904878negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
0.54GO:0048514blood vessel morphogenesis
0.82GO:0043325phosphatidylinositol-3,4-bisphosphate binding
0.82GO:0010314phosphatidylinositol-5-phosphate binding
0.82GO:0070300phosphatidic acid binding
0.79GO:0080025phosphatidylinositol-3,5-bisphosphate binding
0.79GO:0005546phosphatidylinositol-4,5-bisphosphate binding
0.77GO:0070273phosphatidylinositol-4-phosphate binding
0.77GO:0032266phosphatidylinositol-3-phosphate binding
0.44GO:0031210phosphatidylcholine binding
0.43GO:0001786phosphatidylserine binding
0.42GO:00055451-phosphatidylinositol binding
0.75GO:0034704calcium channel complex
0.73GO:0045111intermediate filament cytoskeleton
sp|Q86VW1|S22AG_HUMAN
Solute carrier family 22 member 16
Search
SLC22A16
0.97Epididymis secretory protein Li 18
0.56GO:1902603carnitine transmembrane transport
0.55GO:0015837amine transport
0.54GO:0030317flagellated sperm motility
0.54GO:0007338single fertilization
0.53GO:0046717acid secretion
0.44GO:0015711organic anion transport
0.38GO:0007283spermatogenesis
0.37GO:0030154cell differentiation
0.37GO:0007275multicellular organism development
0.34GO:0009437carnitine metabolic process
0.56GO:0015226carnitine transmembrane transporter activity
0.50GO:0005275amine transmembrane transporter activity
0.45GO:0008514organic anion transmembrane transporter activity
0.39GO:0003884D-amino-acid oxidase activity
0.34GO:0015491cation:cation antiporter activity
0.33GO:0030165PDZ domain binding
0.32GO:0046872metal ion binding
0.32GO:0003677DNA binding
0.36GO:0005887integral component of plasma membrane
0.33GO:0016324apical plasma membrane
0.32GO:0005739mitochondrion
0.39EC:1.4.3.3 GO:0003884
sp|Q86VW2|ARHGP_HUMAN
Rho guanine nucleotide exchange factor 25
Search
ARHGEF25
0.96Guanine nucleotide exchange factor GEFT
0.78GO:0035023regulation of Rho protein signal transduction
0.66GO:0065009regulation of molecular function
0.38GO:0006468protein phosphorylation
0.35GO:1902358sulfate transmembrane transport
0.35GO:0007186G-protein coupled receptor signaling pathway
0.32GO:0043401steroid hormone mediated signaling pathway
0.32GO:0006351transcription, DNA-templated
0.32GO:2000112regulation of cellular macromolecule biosynthetic process
0.32GO:1903506regulation of nucleic acid-templated transcription
0.31GO:0010468regulation of gene expression
0.78GO:0005089Rho guanyl-nucleotide exchange factor activity
0.38GO:0004672protein kinase activity
0.36GO:0032559adenyl ribonucleotide binding
0.36GO:0008144drug binding
0.36GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0015116sulfate transmembrane transporter activity
0.33GO:0015291secondary active transmembrane transporter activity
0.32GO:0003707steroid hormone receptor activity
0.31GO:0003677DNA binding
0.38GO:0030017sarcomere
0.35GO:0005829cytosol
0.34GO:0005886plasma membrane
0.32GO:0005634nucleus
0.30GO:0016021integral component of membrane
sp|Q86VX2|COMD7_HUMAN
COMM domain-containing protein 7
Search
COMMD7
0.97COMM domain-containing protein 7
0.83GO:0033209tumor necrosis factor-mediated signaling pathway
0.83GO:0032088negative regulation of NF-kappaB transcription factor activity
0.70GO:0045892negative regulation of transcription, DNA-templated
0.39GO:0006351transcription, DNA-templated
0.35GO:0006260DNA replication
0.33GO:0055114oxidation-reduction process
0.85GO:0051059NF-kappaB binding
0.36GO:0061731ribonucleoside-diphosphate reductase activity
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.55GO:0043231intracellular membrane-bounded organelle
0.46GO:0031982vesicle
0.44GO:0043230extracellular organelle
0.42GO:0005615extracellular space
0.38GO:0044444cytoplasmic part
0.30GO:0016020membrane
sp|Q86VX9|MON1A_HUMAN
Vacuolar fusion protein MON1 homolog A
Search
MON1A
0.96Vacuolar fusion protein MON1 like protein A
0.64GO:0016192vesicle-mediated transport
0.64GO:0019085early viral transcription
0.63GO:0019086late viral transcription
0.61GO:0009306protein secretion
0.49GO:0065009regulation of molecular function
0.44GO:0006879cellular iron ion homeostasis
0.38GO:0007130synaptonemal complex assembly
0.36GO:0045861negative regulation of proteolysis
0.53GO:0005085guanyl-nucleotide exchange factor activity
0.38GO:0008191metalloendopeptidase inhibitor activity
0.71GO:0035658Mon1-Ccz1 complex
0.39GO:0005829cytosol
0.38GO:0000795synaptonemal complex
0.35GO:0005576extracellular region
sp|Q86VY4|TSYL5_HUMAN
Testis-specific Y-encoded-like protein 5
Search
0.95Testis-specific Y-encoded-like protein 5
0.79GO:0006334nucleosome assembly
0.56GO:0071480cellular response to gamma radiation
0.55GO:0051897positive regulation of protein kinase B signaling
0.53GO:0031398positive regulation of protein ubiquitination
0.52GO:0008284positive regulation of cell proliferation
0.46GO:0040008regulation of growth
0.39GO:0005515protein binding
0.61GO:0005634nucleus
sp|Q86VY9|T200A_HUMAN
Transmembrane protein 200A
Search
TMEM200A
0.51Transmembrane domain-containing protein (Fragment)
0.30GO:0044425membrane part
sp|Q86VZ1|P2RY8_HUMAN
P2Y purinoceptor 8
Search
P2RY8
0.97Purinergic receptor P2Y, G-protein coupled, 8
0.84GO:0035589G-protein coupled purinergic nucleotide receptor signaling pathway
0.69GO:0070493thrombin-activated receptor signaling pathway
0.65GO:0007596blood coagulation
0.50GO:0051482positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.49GO:0035025positive regulation of Rho protein signal transduction
0.34GO:0006886intracellular protein transport
0.33GO:0032259methylation
0.32GO:0007218neuropeptide signaling pathway
0.32GO:0055085transmembrane transport
0.32GO:0035556intracellular signal transduction
0.84GO:0045028G-protein coupled purinergic nucleotide receptor activity
0.69GO:0015057thrombin-activated receptor activity
0.35GO:0047429nucleoside-triphosphate diphosphatase activity
0.34GO:0008171O-methyltransferase activity
0.33GO:0004983neuropeptide Y receptor activity
0.32GO:0022857transmembrane transporter activity
0.42GO:0005887integral component of plasma membrane
0.32GO:0031966mitochondrial membrane
0.32GO:0019866organelle inner membrane
0.35EC:3.6.1.19 GO:0047429
sp|Q86VZ2|WDR5B_HUMAN
WD repeat-containing protein 5B
Search
WDR5B
0.92WD repeat-containing protein 5
0.75GO:0043982histone H4-K8 acetylation
0.75GO:0043981histone H4-K5 acetylation
0.74GO:0043984histone H4-K16 acetylation
0.72GO:0035948positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.71GO:0043966histone H3 acetylation
0.71GO:0051568histone H3-K4 methylation
0.66GO:0060271cilium assembly
0.65GO:0001501skeletal system development
0.43GO:0031175neuron projection development
0.39GO:0045652regulation of megakaryocyte differentiation
0.76GO:0043996histone acetyltransferase activity (H4-K8 specific)
0.76GO:0046972histone acetyltransferase activity (H4-K16 specific)
0.76GO:0043995histone acetyltransferase activity (H4-K5 specific)
0.71GO:0042800histone methyltransferase activity (H3-K4 specific)
0.71GO:0140034methylation-dependent protein binding
0.67GO:0042393histone binding
0.39GO:0016905myosin heavy chain kinase activity
0.72GO:0005671Ada2/Gcn5/Ada3 transcription activator complex
0.72GO:0044666MLL3/4 complex
0.70GO:0071339MLL1 complex
0.69GO:0048188Set1C/COMPASS complex
0.68GO:0036064ciliary basal body
0.41GO:0019013viral nucleocapsid
0.38GO:0030529intracellular ribonucleoprotein complex
0.30GO:0016020membrane
0.39EC:2.7.11.7 GO:0016905
sp|Q86VZ4|LRP11_HUMAN
Low-density lipoprotein receptor-related protein 11
Search
LRP11
0.93Low-density lipoprotein receptor-related protein 11
0.58GO:0035902response to immobilization stress
0.55GO:0033555multicellular organismal response to stress
0.54GO:0009612response to mechanical stimulus
0.54GO:0009414response to water deprivation
0.53GO:0009409response to cold
0.52GO:0042594response to starvation
0.51GO:0009408response to heat
0.44GO:0010951negative regulation of endopeptidase activity
0.35GO:0006897endocytosis
0.34GO:2000171negative regulation of dendrite development
0.58GO:0051219phosphoprotein binding
0.45GO:0004867serine-type endopeptidase inhibitor activity
0.33GO:0008233peptidase activity
0.34GO:0005886plasma membrane
0.33GO:0005769early endosome
0.32GO:0043231intracellular membrane-bounded organelle
0.30GO:0031224intrinsic component of membrane
0.33EC:3.4 GO:0008233
sp|Q86VZ5|SMS1_HUMAN
Phosphatidylcholine:ceramide cholinephosphotransferase 1
Search
SGMS1
0.69Phosphatidylcholine:ceramide cholinephosphotransferase 1
0.61GO:0046513ceramide biosynthetic process
0.56GO:2001237negative regulation of extrinsic apoptotic signaling pathway
0.53GO:0006686sphingomyelin biosynthetic process
0.40GO:1905371ceramide phosphoethanolamine metabolic process
0.40GO:0006915apoptotic process
0.39GO:0006954inflammatory response
0.38GO:0071356cellular response to tumor necrosis factor
0.38GO:0071222cellular response to lipopolysaccharide
0.37GO:0010628positive regulation of gene expression
0.36GO:0016310phosphorylation
0.64GO:0033188sphingomyelin synthase activity
0.62GO:0002950ceramide phosphoethanolamine synthase activity
0.53GO:0047493ceramide cholinephosphotransferase activity
0.36GO:0016301kinase activity
0.33GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32GO:0020037heme binding
0.32GO:0005506iron ion binding
0.50GO:0030173integral component of Golgi membrane
0.47GO:0030176integral component of endoplasmic reticulum membrane
0.44GO:0005887integral component of plasma membrane
0.39GO:0000138Golgi trans cisterna
0.34GO:0005634nucleus
0.64EC:2.7.8.27 GO:0033188
0.64KEGG:R08969 GO:0033188
sp|Q86VZ6|JAZF1_HUMAN
Juxtaposed with another zinc finger protein 1
Search
JAZF1
0.97Juxtaposed with another zinc finger protein 1
0.50GO:0000122negative regulation of transcription by RNA polymerase II
0.43GO:0007368determination of left/right symmetry
0.42GO:0060271cilium assembly
0.35GO:0006629lipid metabolic process
0.34GO:0006351transcription, DNA-templated
0.33GO:0045944positive regulation of transcription by RNA polymerase II
0.32GO:0055085transmembrane transport
0.52GO:0003714transcription corepressor activity
0.51GO:0003676nucleic acid binding
0.34GO:0046872metal ion binding
0.33GO:0001076transcription factor activity, RNA polymerase II transcription factor binding
0.54GO:0001650fibrillar center
0.52GO:0017053transcriptional repressor complex
0.47GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q86W10|CP4Z1_HUMAN
Cytochrome P450 4Z1
Search
0.94Fatty acid omega-hydroxylase
0.53GO:0055114oxidation-reduction process
0.42GO:0006690icosanoid metabolic process
0.42GO:0033559unsaturated fatty acid metabolic process
0.41GO:0001676long-chain fatty acid metabolic process
0.39GO:1901569fatty acid derivative catabolic process
0.39GO:0048252lauric acid metabolic process
0.38GO:0009062fatty acid catabolic process
0.38GO:1901616organic hydroxy compound catabolic process
0.37GO:0003095pressure natriuresis
0.37GO:1901570fatty acid derivative biosynthetic process
0.68GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.64GO:0004497monooxygenase activity
0.63GO:0020037heme binding
0.63GO:0005506iron ion binding
0.43GO:010300216-hydroxypalmitate dehydrogenase activity
0.35GO:0050544arachidonic acid binding
0.34GO:0019825oxygen binding
0.42GO:0005789endoplasmic reticulum membrane
0.39GO:0016324apical plasma membrane
0.39GO:0005615extracellular space
0.38GO:0031090organelle membrane
0.34GO:1903561extracellular vesicle
0.30GO:0031224intrinsic component of membrane
0.68EC:1.14 GO:0016705
sp|Q86W11|ZSC30_HUMAN
Zinc finger and SCAN domain-containing protein 30
Search
ZSCAN30
0.86Zinc finger and SCAN domain-containing protein 30
0.54GO:1903506regulation of nucleic acid-templated transcription
0.54GO:2000112regulation of cellular macromolecule biosynthetic process
0.53GO:0010468regulation of gene expression
0.50GO:0006351transcription, DNA-templated
0.35GO:1902679negative regulation of RNA biosynthetic process
0.35GO:1902680positive regulation of RNA biosynthetic process
0.34GO:0042552myelination
0.33GO:0007010cytoskeleton organization
0.33GO:0022604regulation of cell morphogenesis
0.55GO:0003700DNA binding transcription factor activity
0.50GO:0003676nucleic acid binding
0.50GO:0046872metal ion binding
0.36GO:0005515protein binding
0.55GO:0005634nucleus
0.34GO:0015630microtubule cytoskeleton
0.34GO:0005829cytosol
0.33GO:0043233organelle lumen
0.33GO:0044446intracellular organelle part
0.33GO:0005886plasma membrane
sp|Q86W24|NAL14_HUMAN
NACHT, LRR and PYD domains-containing protein 14
Search
NLRP12
0.89NLR family pyrin domain containing 2
0.60GO:0007283spermatogenesis
0.56GO:0008588release of cytoplasmic sequestered NF-kappaB
0.56GO:0050704regulation of interleukin-1 secretion
0.56GO:0045345positive regulation of MHC class I biosynthetic process
0.56GO:0045751negative regulation of Toll signaling pathway
0.55GO:0045409negative regulation of interleukin-6 biosynthetic process
0.55GO:0032692negative regulation of interleukin-1 production
0.55GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.55GO:0031953negative regulation of protein autophosphorylation
0.54GO:0032088negative regulation of NF-kappaB transcription factor activity
0.55GO:0030554adenyl nucleotide binding
0.54GO:0097367carbohydrate derivative binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.54GO:0008144drug binding
0.41GO:0019904protein domain specific binding
0.39GO:0019899enzyme binding
0.37GO:0019828aspartic-type endopeptidase inhibitor activity
0.36GO:0019966interleukin-1 binding
0.43GO:0061702inflammasome complex
0.39GO:0031981nuclear lumen
0.38GO:0000781chromosome, telomeric region
0.37GO:0005794Golgi apparatus
sp|Q86W25|NAL13_HUMAN
NACHT, LRR and PYD domains-containing protein 13
Search
NLRP13
0.95NACHT, LRR and PYD domains-containing protein 13
0.49GO:0008588release of cytoplasmic sequestered NF-kappaB
0.49GO:0045345positive regulation of MHC class I biosynthetic process
0.49GO:0045751negative regulation of Toll signaling pathway
0.49GO:0045409negative regulation of interleukin-6 biosynthetic process
0.48GO:0050711negative regulation of interleukin-1 secretion
0.48GO:0031953negative regulation of protein autophosphorylation
0.47GO:0032088negative regulation of NF-kappaB transcription factor activity
0.47GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling
0.46GO:0050728negative regulation of inflammatory response
0.46GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.36GO:0032090Pyrin domain binding
0.35GO:0008656cysteine-type endopeptidase activator activity involved in apoptotic process
0.30GO:0003824catalytic activity
0.36GO:0005737cytoplasm
0.36GO:0005634nucleus
0.35GO:0043233organelle lumen
0.34GO:0000781chromosome, telomeric region
0.33GO:0012505endomembrane system
0.32GO:0043234protein complex
sp|Q86W26|NAL10_HUMAN
NACHT, LRR and PYD domains-containing protein 10
Search
NLRP10
0.95NLR family pyrin domain containing 10
0.70GO:0050704regulation of interleukin-1 secretion
0.66GO:0032730positive regulation of interleukin-1 alpha production
0.66GO:0032675regulation of interleukin-6 production
0.65GO:2000484positive regulation of interleukin-8 secretion
0.64GO:1900426positive regulation of defense response to bacterium
0.62GO:0050727regulation of inflammatory response
0.61GO:2000318positive regulation of T-helper 17 type immune response
0.61GO:0050829defense response to Gram-negative bacterium
0.60GO:0002827positive regulation of T-helper 1 type immune response
0.56GO:0050832defense response to fungus
0.55GO:0030554adenyl nucleotide binding
0.54GO:0097367carbohydrate derivative binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.54GO:0008144drug binding
0.52GO:0003924GTPase activity
0.48GO:0016887ATPase activity
0.42GO:0019904protein domain specific binding
0.41GO:0019899enzyme binding
0.38GO:0042802identical protein binding
0.57GO:0019897extrinsic component of plasma membrane
0.49GO:0061702inflammasome complex
0.40GO:0005654nucleoplasm
0.30GO:0016021integral component of membrane
0.48EC:3.6.1.3 GO:0016887
sp|Q86W28|NALP8_HUMAN
NACHT, LRR and PYD domains-containing protein 8
Search
NLRP8
0.94NACHT, LRR and PYD domains-containing protein 8
0.58GO:0070997neuron death
0.48GO:0007283spermatogenesis
0.46GO:0002674negative regulation of acute inflammatory response
0.46GO:0050713negative regulation of interleukin-1 beta secretion
0.45GO:0042347negative regulation of NF-kappaB import into nucleus
0.45GO:0050718positive regulation of interleukin-1 beta secretion
0.44GO:0032088negative regulation of NF-kappaB transcription factor activity
0.44GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44GO:0051092positive regulation of NF-kappaB transcription factor activity
0.44GO:0071222cellular response to lipopolysaccharide
0.54GO:0030554adenyl nucleotide binding
0.53GO:0097367carbohydrate derivative binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.53GO:0008144drug binding
0.41GO:0042802identical protein binding
0.39GO:0008134transcription factor binding
0.37GO:0043565sequence-specific DNA binding
0.30GO:0003824catalytic activity
0.47GO:0061702inflammasome complex
0.37GO:0005634nucleus
0.36GO:0048471perinuclear region of cytoplasm
0.36GO:0005783endoplasmic reticulum
0.35GO:0005938cell cortex
0.35GO:0005576extracellular region
0.33GO:0070013intracellular organelle lumen
0.33GO:0005739mitochondrion
0.33GO:0043232intracellular non-membrane-bounded organelle
0.33GO:0044446intracellular organelle part
sp|Q86W33|TPRA1_HUMAN
Transmembrane protein adipocyte-associated 1
Search
TPRA1
0.96Transmembrane protein adipocyte-associated 1
0.60GO:0040016embryonic cleavage
0.55GO:1901991negative regulation of mitotic cell cycle phase transition
0.35GO:0007568aging
0.34GO:0007186G-protein coupled receptor signaling pathway
0.34GO:0006629lipid metabolic process
0.34GO:0004930G-protein coupled receptor activity
0.34GO:0005515protein binding
0.32GO:0046872metal ion binding
0.34GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q86W34|AMZ2_HUMAN
Archaemetzincin-2
Search
AMZ2
0.97Archaemetzincin-2
0.60GO:0006508proteolysis
0.67GO:0008237metallopeptidase activity
0.63GO:0008270zinc ion binding
sp|Q86W42|THOC6_HUMAN
THO complex subunit 6 homolog
Search
THOC6
0.96THO complex subunit 6
0.86GO:0046784viral mRNA export from host cell nucleus
0.78GO:0071427mRNA-containing ribonucleoprotein complex export from nucleus
0.76GO:0007417central nervous system development
0.76GO:0043066negative regulation of apoptotic process
0.74GO:0051028mRNA transport
0.73GO:0006405RNA export from nucleus
0.53GO:0010467gene expression
0.48GO:0006915apoptotic process
0.45GO:0016071mRNA metabolic process
0.36GO:0097659nucleic acid-templated transcription
0.41GO:0003723RNA binding
0.37GO:0005515protein binding
0.83GO:0000445THO complex part of transcription export complex
0.79GO:0000784nuclear chromosome, telomeric region
0.78GO:0016607nuclear speck
sp|Q86W47|KCMB4_HUMAN
Calcium-activated potassium channel subunit beta-4
Search
KCNMB4
0.97Calcium-activated potassium channel subunit beta-4
0.73GO:0071805potassium ion transmembrane transport
0.70GO:0005513detection of calcium ion
0.67GO:0019228neuronal action potential
0.48GO:0007268chemical synaptic transmission
0.44GO:0065009regulation of molecular function
0.37GO:0046928regulation of neurotransmitter secretion
0.37GO:0019229regulation of vasoconstriction
0.84GO:0015269calcium-activated potassium channel activity
0.52GO:0015459potassium channel regulator activity
0.36GO:0005515protein binding
0.61GO:0008076voltage-gated potassium channel complex
sp|Q86W50|MET16_HUMAN
Methyltransferase-like protein 16
Search
METTL16
0.82Methyltransferase 10 domain containing (Fragment)
0.63GO:0032259methylation
0.61GO:0120049snRNA (adenine-N6)-methylation
0.56GO:0061157mRNA destabilization
0.56GO:0048024regulation of mRNA splicing, via spliceosome
0.54GO:0016556mRNA modification
0.50GO:0006402mRNA catabolic process
0.44GO:0000154rRNA modification
0.38GO:0008380RNA splicing
0.37GO:0006397mRNA processing
0.36GO:0000132establishment of mitotic spindle orientation
0.63GO:0008168methyltransferase activity
0.61GO:0030629U6 snRNA 3'-end binding
0.58GO:0035613RNA stem-loop binding
0.47GO:0140098catalytic activity, acting on RNA
0.36GO:0070840dynein complex binding
0.34GO:0046983protein dimerization activity
0.34GO:0003887DNA-directed DNA polymerase activity
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.46GO:0005634nucleus
0.35GO:0005875microtubule associated complex
0.35GO:0005815microtubule organizing center
0.35GO:0005874microtubule
0.32GO:0005737cytoplasm
0.30GO:0016020membrane
0.63EC:2.1.1 GO:0008168
sp|Q86W54|SPA24_HUMAN
Spermatogenesis-associated protein 24
Search
SPATA24
0.97Spermatogenesis-associated protein 24
0.49GO:0007283spermatogenesis
0.46GO:0030154cell differentiation
0.45GO:0007275multicellular organism development
0.41GO:0006351transcription, DNA-templated
0.40GO:2001141regulation of RNA biosynthetic process
0.40GO:2000112regulation of cellular macromolecule biosynthetic process
0.40GO:0010468regulation of gene expression
0.71GO:0042803protein homodimerization activity
0.53GO:0003677DNA binding
0.66GO:0005829cytosol
0.61GO:0005634nucleus
0.44GO:0031974membrane-enclosed lumen
0.41GO:0043232intracellular non-membrane-bounded organelle
0.41GO:0044446intracellular organelle part
0.30GO:0031224intrinsic component of membrane
sp|Q86W56|PARG_HUMAN
Poly(ADP-ribose) glycohydrolase
Search
PARG
0.86Poly (ADP-ribose) glycohydrolase
0.63GO:1990966ATP generation from poly-ADP-D-ribose
0.60GO:0005975carbohydrate metabolic process
0.38GO:0016045detection of bacterium
0.36GO:0045739positive regulation of DNA repair
0.35GO:0006974cellular response to DNA damage stimulus
0.34GO:0006334nucleosome assembly
0.34GO:0006468protein phosphorylation
0.85GO:0004649poly(ADP-ribose) glycohydrolase activity
0.35GO:0003682chromatin binding
0.35GO:0005515protein binding
0.35GO:0004683calmodulin-dependent protein kinase activity
0.32GO:0030554adenyl nucleotide binding
0.32GO:0097367carbohydrate derivative binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.50GO:0005654nucleoplasm
0.50GO:0005829cytosol
0.35GO:0005759mitochondrial matrix
0.34GO:0000785chromatin
0.30GO:0031224intrinsic component of membrane
0.85EC:3.2.1.143 GO:0004649
sp|Q86W67|F228A_HUMAN
Protein FAM228A
Search
sp|Q86W74|ANR46_HUMAN
Ankyrin repeat domain-containing protein 46
Search
ANKRD46
0.97Ankyrin repeat domain-containing protein 46
0.36GO:0006886intracellular protein transport
0.36GO:0035091phosphatidylinositol binding
0.32GO:0005622intracellular
0.30GO:0016020membrane
sp|Q86W92|LIPB1_HUMAN
Liprin-beta-1
Search
PPFIBP1
0.92PTPRF interacting protein binding protein 1
0.41GO:0007155cell adhesion
0.37GO:0000187activation of MAPK activity
0.36GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
0.36GO:0048666neuron development
0.36GO:0018108peptidyl-tyrosine phosphorylation
0.81GO:0045296cadherin binding
0.36GO:0004714transmembrane receptor protein tyrosine kinase activity
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.50GO:0005925focal adhesion
0.40GO:0005829cytosol
0.37GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
0.36EC:2.7.10.1 GO:0004714
sp|Q86WA6|BPHL_HUMAN
Valacyclovir hydrolase
Search
BPHL
0.75Biphenyl hydrolase like
0.36GO:1990966ATP generation from poly-ADP-D-ribose
0.35GO:0070926regulation of ATP:ADP antiporter activity
0.35GO:0060545positive regulation of necroptotic process
0.35GO:0097343ripoptosome assembly
0.35GO:0036289peptidyl-serine autophosphorylation
0.35GO:1905206positive regulation of hydrogen peroxide-induced cell death
0.35GO:1990000amyloid fibril formation
0.35GO:0097527necroptotic signaling pathway
0.35GO:0045651positive regulation of macrophage differentiation
0.35GO:0006805xenobiotic metabolic process
0.47GO:0016787hydrolase activity
0.35GO:0005123death receptor binding
0.35GO:0070513death domain binding
0.34GO:0031625ubiquitin protein ligase binding
0.34GO:0032403protein complex binding
0.34GO:0042802identical protein binding
0.33GO:0004674protein serine/threonine kinase activity
0.32GO:0030554adenyl nucleotide binding
0.32GO:0015035protein disulfide oxidoreductase activity
0.32GO:0097367carbohydrate derivative binding
0.46GO:0005739mitochondrion
0.37GO:0070062extracellular exosome
0.35GO:0031264death-inducing signaling complex
0.35GO:0097342ripoptosome
0.35GO:0031968organelle outer membrane
0.34GO:0043235receptor complex
0.33GO:0005634nucleus
0.47EC:3 GO:0016787
sp|Q86WA8|LONP2_HUMAN
Lon protease homolog 2, peroxisomal
Search
LONP2
0.75Lon protease homolog 2, peroxisomal
0.73GO:0006515protein quality control for misfolded or incompletely synthesized proteins
0.70GO:0072663establishment of protein localization to peroxisome
0.70GO:0043574peroxisomal transport
0.67GO:0044743protein transmembrane import into intracellular organelle
0.65GO:0016485protein processing
0.63GO:0065002intracellular protein transmembrane transport
0.62GO:0006605protein targeting
0.62GO:0031998regulation of fatty acid beta-oxidation
0.38GO:0014070response to organic cyclic compound
0.75GO:0004176ATP-dependent peptidase activity
0.68GO:0004252serine-type endopeptidase activity
0.59GO:0002020protease binding
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.53GO:0005102receptor binding
0.33GO:0043565sequence-specific DNA binding
0.74GO:0031907microbody lumen
0.68GO:0044439peroxisomal part
0.46GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
0.68EC:3.4.21 GO:0004252
sp|Q86WA9|S2611_HUMAN
Sodium-independent sulfate anion transporter
Search
SLC26A11
0.83Sodium-independent sulfate anion transporter
0.75GO:1902358sulfate transmembrane transport
0.51GO:0015701bicarbonate transport
0.51GO:0019532oxalate transport
0.50GO:0051453regulation of intracellular pH
0.48GO:0042391regulation of membrane potential
0.47GO:1902476chloride transmembrane transport
0.34GO:0016567protein ubiquitination
0.32GO:0051276chromosome organization
0.78GO:0008271secondary active sulfate transmembrane transporter activity
0.52GO:0015106bicarbonate transmembrane transporter activity
0.51GO:0019531oxalate transmembrane transporter activity
0.50GO:0015301anion:anion antiporter activity
0.48GO:0005254chloride channel activity
0.34GO:0004842ubiquitin-protein transferase activity
0.33GO:0016887ATPase activity
0.33GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.56GO:0005765lysosomal membrane
0.51GO:0005794Golgi apparatus
0.50GO:0005783endoplasmic reticulum
0.50GO:0005654nucleoplasm
0.44GO:0005886plasma membrane
0.37GO:0070062extracellular exosome
0.32GO:0005694chromosome
0.30GO:0016021integral component of membrane
0.33EC:3.6.1.3 GO:0016887
0.34KEGG:R03876 GO:0004842
sp|Q86WB0|NIPA_HUMAN
Nuclear-interacting partner of ALK
Search
ZC3HC1
0.91Nuclear-interacting partner of ALK
0.52GO:1901099negative regulation of signal transduction in absence of ligand
0.51GO:2001239regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.50GO:2001237negative regulation of extrinsic apoptotic signaling pathway
0.42GO:0016567protein ubiquitination
0.41GO:0051301cell division
0.41GO:0007049cell cycle
0.63GO:0008270zinc ion binding
0.49GO:0019901protein kinase binding
0.61GO:0005634nucleus
0.45GO:0012505endomembrane system
0.43GO:0031967organelle envelope
0.43GO:0031090organelle membrane
sp|Q86WB7|UN93A_HUMAN
Protein unc-93 homolog A
Search
UNC93A
0.97Unc-93 homolog A (C. elegans)
0.36GO:0055085transmembrane transport
0.34GO:0043266regulation of potassium ion transport
0.34GO:0006464cellular protein modification process
0.34GO:0006937regulation of muscle contraction
0.33GO:0008643carbohydrate transport
0.33GO:0065009regulation of molecular function
0.34GO:0015459potassium channel regulator activity
0.33GO:0030554adenyl nucleotide binding
0.33GO:0097367carbohydrate derivative binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.41GO:0005886plasma membrane
0.34GO:0055120striated muscle dense body
0.30GO:0044425membrane part
sp|Q86WC4|OSTM1_HUMAN
Osteopetrosis-associated transmembrane protein 1
Search
OSTM1
0.95Osteopetrosis-associated transmembrane protein 1
0.63GO:0030316osteoclast differentiation
0.34GO:0034220ion transmembrane transport
0.34GO:0005515protein binding
0.52GO:0005829cytosol
0.38GO:0005765lysosomal membrane
0.30GO:0031224intrinsic component of membrane
sp|Q86WC6|PPR27_HUMAN
Protein phosphatase 1 regulatory subunit 27
Search
PPP1R27
0.97Dysferlin-interacting protein 1
0.76GO:0010923negative regulation of phosphatase activity
0.43GO:0035308negative regulation of protein dephosphorylation
0.42GO:0043666regulation of phosphoprotein phosphatase activity
0.39GO:0007253cytoplasmic sequestering of NF-kappaB
0.38GO:0090201negative regulation of release of cytochrome c from mitochondria
0.38GO:0043518negative regulation of DNA damage response, signal transduction by p53 class mediator
0.38GO:0032088negative regulation of NF-kappaB transcription factor activity
0.38GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.38GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.37GO:0070682proteasome regulatory particle assembly
0.77GO:0019902phosphatase binding
0.43GO:0004864protein phosphatase inhibitor activity
0.38GO:0008134transcription factor binding
0.38GO:0030374ligand-dependent nuclear receptor transcription coactivator activity
0.38GO:0051427hormone receptor binding
0.36GO:0047389glycerophosphocholine phosphodiesterase activity
0.36GO:0002039p53 binding
0.35GO:0018024histone-lysine N-methyltransferase activity
0.35GO:0008270zinc ion binding
0.35GO:0004067asparaginase activity
0.42GO:1905369endopeptidase complex
0.38GO:0043234protein complex
0.38GO:0005634nucleus
0.37GO:0045111intermediate filament cytoskeleton
0.35GO:0005829cytosol
0.35GO:0005694chromosome
0.33GO:0000151ubiquitin ligase complex
0.33GO:0043233organelle lumen
0.32GO:0044446intracellular organelle part
0.30GO:0016020membrane
0.36EC:3.1.4.2 GO:0047389
0.33KEGG:R03876 GO:0004842
sp|Q86WD7|SPA9_HUMAN
Serpin A9
Search
SERPINA7
0.91Thyroxine-binding globulin
0.56GO:0010951negative regulation of endopeptidase activity
0.51GO:0070327thyroid hormone transport
0.41GO:0007283spermatogenesis
0.39GO:0008211glucocorticoid metabolic process
0.36GO:0061107seminal vesicle development
0.35GO:0007338single fertilization
0.35GO:0006508proteolysis
0.35GO:0033189response to vitamin A
0.35GO:0051412response to corticosterone
0.35GO:0034695response to prostaglandin E
0.58GO:0004867serine-type endopeptidase inhibitor activity
0.43GO:0032190acrosin binding
0.43GO:0001972retinoic acid binding
0.43GO:0031210phosphatidylcholine binding
0.42GO:0002020protease binding
0.39GO:0005496steroid binding
0.35GO:0008233peptidase activity
0.35GO:0008201heparin binding
0.35GO:0015349thyroid hormone transmembrane transporter activity
0.34GO:0042562hormone binding
0.73GO:0005615extracellular space
0.44GO:0097182protein C inhibitor-coagulation factor Xa complex
0.44GO:0097183protein C inhibitor-coagulation factor XI complex
0.44GO:0097181protein C inhibitor-coagulation factor V complex
0.44GO:0036030protein C inhibitor-plasma kallikrein complex
0.44GO:0036028protein C inhibitor-thrombin complex
0.44GO:0036029protein C inhibitor-KLK3 complex
0.44GO:0036024protein C inhibitor-TMPRSS7 complex
0.44GO:0036025protein C inhibitor-TMPRSS11E complex
0.44GO:0036026protein C inhibitor-PLAT complex
0.35EC:3.4 GO:0008233
sp|Q86WG3|ATCAY_HUMAN
Caytaxin
Search
ATCAY
0.97Ataxia, cerebellar, Cayman type b
0.74GO:2000212negative regulation of glutamate metabolic process
0.62GO:0031175neuron projection development
0.60GO:0032880regulation of protein localization
0.50GO:0032222regulation of synaptic transmission, cholinergic
0.45GO:0048311mitochondrion distribution
0.38GO:0035418protein localization to synapse
0.36GO:0006915apoptotic process
0.34GO:0055114oxidation-reduction process
0.33GO:1903506regulation of nucleic acid-templated transcription
0.33GO:2000112regulation of cellular macromolecule biosynthetic process
0.67GO:0019894kinesin binding
0.45GO:0050699WW domain binding
0.37GO:0016641oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.36GO:0005507copper ion binding
0.36GO:0016462pyrophosphatase activity
0.36GO:0042802identical protein binding
0.35GO:0015293symporter activity
0.34GO:0008270zinc ion binding
0.34GO:0003700DNA binding transcription factor activity
0.63GO:0043005neuron projection
0.51GO:0031966mitochondrial membrane
0.44GO:0036477somatodendritic compartment
0.43GO:0120038plasma membrane bounded cell projection part
0.43GO:0045202synapse
0.41GO:0030054cell junction
0.35GO:0005829cytosol
0.30GO:0016021integral component of membrane
0.37EC:1.4.3 GO:0016641
sp|Q86WG5|MTMRD_HUMAN
Myotubularin-related protein 13
Search
SBF2
0.92SET binding factor 2
0.75GO:0043087regulation of GTPase activity
0.61GO:0051262protein tetramerization
0.79GO:0019208phosphatase regulator activity
0.64GO:0017112Rab guanyl-nucleotide exchange factor activity
0.63GO:0019902phosphatase binding
0.59GO:0035091phosphatidylinositol binding
0.58GO:0042803protein homodimerization activity
0.59GO:0005774vacuolar membrane
0.35GO:0005829cytosol
sp|Q86WH2|RASF3_HUMAN
Ras association domain-containing protein 3
Search
RASSF3
0.97Ras association domain-containing protein 3
0.71GO:0042981regulation of apoptotic process
0.60GO:0007165signal transduction
0.47GO:0070507regulation of microtubule cytoskeleton organization
0.33GO:0007050cell cycle arrest
0.49GO:0042802identical protein binding
0.36GO:0046872metal ion binding
0.33GO:0017016Ras GTPase binding
0.46GO:0005829cytosol
0.41GO:0005886plasma membrane
0.36GO:0015630microtubule cytoskeleton
0.36GO:0099513polymeric cytoskeletal fiber
0.32GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
sp|Q86WI0|LHPL1_HUMAN
Lipoma HMGIC fusion partner-like 1 protein
Search
0.96LHFPL tetraspan subfamily member 1
0.30GO:0044425membrane part
sp|Q86WI1|PKHL1_HUMAN
Fibrocystin-L
Search
0.64fibrocystin-L
0.46GO:0021785branchiomotor neuron axon guidance
0.46GO:0048841regulation of axon extension involved in axon guidance
0.44GO:0071526semaphorin-plexin signaling pathway
0.41GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.40GO:0000272polysaccharide catabolic process
0.33GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
0.33GO:0018108peptidyl-tyrosine phosphorylation
0.32GO:0006413translational initiation
0.30GO:0006955immune response
0.45GO:0017154semaphorin receptor activity
0.43GO:0005509calcium ion binding
0.40GO:0008017microtubule binding
0.33GO:0004714transmembrane receptor protein tyrosine kinase activity
0.32GO:0003743translation initiation factor activity
0.32GO:0003924GTPase activity
0.32GO:0032550purine ribonucleoside binding
0.32GO:0032561guanyl ribonucleotide binding
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.54GO:0005929cilium
0.39GO:0005856cytoskeleton
0.36GO:0005886plasma membrane
0.30GO:0005615extracellular space
0.30GO:0005737cytoplasm
0.30GO:0016021integral component of membrane
0.33EC:2.7.10.1 GO:0004714
sp|Q86WI3|NLRC5_HUMAN
Protein NLRC5
Search
NLRC5
0.94NLR family CARD domain containing 5
0.85GO:0045345positive regulation of MHC class I biosynthetic process
0.85GO:0060332positive regulation of response to interferon-gamma
0.85GO:0060340positive regulation of type I interferon-mediated signaling pathway
0.84GO:0060334regulation of interferon-gamma-mediated signaling pathway
0.80GO:0032088negative regulation of NF-kappaB transcription factor activity
0.74GO:0045087innate immune response
0.73GO:0051607defense response to virus
0.71GO:0043549regulation of kinase activity
0.71GO:0045944positive regulation of transcription by RNA polymerase II
0.71GO:0060339negative regulation of type I interferon-mediated signaling pathway
0.82GO:0000979RNA polymerase II core promoter sequence-specific DNA binding
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.73GO:0005813centrosome
0.65GO:0005829cytosol
0.58GO:0005634nucleus
0.32GO:0048471perinuclear region of cytoplasm
sp|Q86WJ1|CHD1L_HUMAN
Chromodomain-helicase-DNA-binding protein 1-like
Search
CHD1L
0.97Chromodomain helicase DNA binding protein 1 like
0.76GO:0006338chromatin remodeling
0.68GO:0032392DNA geometric change
0.63GO:0006974cellular response to DNA damage stimulus
0.58GO:0006259DNA metabolic process
0.70GO:0004003ATP-dependent DNA helicase activity
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.55GO:0005654nucleoplasm
0.54GO:0005829cytosol
0.46GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q86WK6|AMGO1_HUMAN
Amphoterin-induced protein 1
Search
AMIGO1
0.89Adhesion molecule with Ig like domain 1
0.83GO:0007413axonal fasciculation
0.80GO:0042552myelination
0.69GO:0007155cell adhesion
0.63GO:0051965positive regulation of synapse assembly
0.61GO:1901381positive regulation of potassium ion transmembrane transport
0.50GO:0065009regulation of molecular function
0.44GO:0043066negative regulation of apoptotic process
0.43GO:0007420brain development
0.41GO:0050772positive regulation of axonogenesis
0.40GO:0007409axonogenesis
0.62GO:0015459potassium channel regulator activity
0.36GO:0005515protein binding
0.64GO:0005887integral component of plasma membrane
0.63GO:0032809neuronal cell body membrane
0.58GO:0030425dendrite
0.56GO:0034705potassium channel complex
0.41GO:0043204perikaryon
0.38GO:0030424axon
0.33GO:0005634nucleus
sp|Q86WK7|AMGO3_HUMAN
Amphoterin-induced protein 3
Search
AMIGO3
0.95Adhesion molecule with Ig like domain 3
0.72GO:0051965positive regulation of synapse assembly
0.51GO:0007413axonal fasciculation
0.50GO:0042552myelination
0.48GO:1901381positive regulation of potassium ion transmembrane transport
0.46GO:0007155cell adhesion
0.42GO:0065009regulation of molecular function
0.35GO:0043066negative regulation of apoptotic process
0.48GO:0015459potassium channel regulator activity
0.49GO:0032809neuronal cell body membrane
0.46GO:0030425dendrite
0.45GO:0008076voltage-gated potassium channel complex
sp|Q86WK9|MPRA_HUMAN
Membrane progestin receptor alpha
Search
PAQR7
0.97Membrane progestin receptor alpha-B
0.50GO:0048545response to steroid hormone
0.49GO:0071396cellular response to lipid
0.49GO:0071407cellular response to organic cyclic compound
0.49GO:0009755hormone-mediated signaling pathway
0.44GO:0048477oogenesis
0.42GO:0007193adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.42GO:0000187activation of MAPK activity
0.42GO:0071695anatomical structure maturation
0.42GO:0048469cell maturation
0.38GO:0007275multicellular organism development
0.52GO:0005496steroid binding
0.50GO:0003707steroid hormone receptor activity
0.42GO:0005886plasma membrane
0.37GO:0005794Golgi apparatus
0.30GO:0016021integral component of membrane
sp|Q86WN1|FCSD1_HUMAN
F-BAR and double SH3 domains protein 1
Search
FCHSD1
0.94F-BAR and double SH3 domains protein 1
0.85GO:0007274neuromuscular synaptic transmission
0.77GO:0030833regulation of actin filament polymerization
0.39GO:0045886negative regulation of synaptic growth at neuromuscular junction
0.39GO:0001881receptor recycling
0.37GO:0051336regulation of hydrolase activity
0.37GO:0043085positive regulation of catalytic activity
0.35GO:0030835negative regulation of actin filament depolymerization
0.35GO:0032272negative regulation of protein polymerization
0.35GO:0007165signal transduction
0.34GO:0071420cellular response to histamine
0.37GO:0005096GTPase activator activity
0.37GO:0005547phosphatidylinositol-3,4,5-trisphosphate binding
0.35GO:0005509calcium ion binding
0.35GO:0005515protein binding
0.34GO:0004869cysteine-type endopeptidase inhibitor activity
0.33GO:0060090molecular adaptor activity
0.84GO:0031594neuromuscular junction
0.82GO:0055037recycling endosome
0.35GO:0008290F-actin capping protein complex
0.34GO:0072686mitotic spindle
0.33GO:0030479actin cortical patch
0.32GO:0005634nucleus
sp|Q86WN2|IFNE_HUMAN
Interferon epsilon
Search
IFNE
0.96Interferon-alphaomega
0.77GO:0051607defense response to virus
0.75GO:0010469regulation of receptor activity
0.62GO:0033141positive regulation of peptidyl-serine phosphorylation of STAT protein
0.61GO:0002323natural killer cell activation involved in immune response
0.60GO:0042100B cell proliferation
0.60GO:0002286T cell activation involved in immune response
0.60GO:0043330response to exogenous dsRNA
0.59GO:0042742defense response to bacterium
0.59GO:0030183B cell differentiation
0.58GO:0002250adaptive immune response
0.80GO:0005125cytokine activity
0.79GO:0005126cytokine receptor binding
0.53GO:0032403protein complex binding
0.37GO:0008811chloramphenicol O-acetyltransferase activity
0.73GO:0005615extracellular space
0.37EC:2.3.1.28 GO:0008811
0.37KEGG:R03065 GO:0008811
sp|Q86WP2|GPBP1_HUMAN
Vasculin
Search
GPBP1
0.97Z-linked GC-rich promoter binding protein 1
0.72GO:0045893positive regulation of transcription, DNA-templated
0.57GO:0006351transcription, DNA-templated
0.32GO:0006915apoptotic process
0.32GO:0043043peptide biosynthetic process
0.32GO:0042981regulation of apoptotic process
0.32GO:0019538protein metabolic process
0.60GO:0003700DNA binding transcription factor activity
0.42GO:0003677DNA binding
0.35GO:0005515protein binding
0.32GO:0003735structural constituent of ribosome
0.32GO:0004197cysteine-type endopeptidase activity
0.60GO:0005634nucleus
0.47GO:0005829cytosol
0.42GO:0005886plasma membrane
0.34GO:0043233organelle lumen
0.33GO:0032991macromolecular complex
0.33GO:0044446intracellular organelle part
0.32GO:0043232intracellular non-membrane-bounded organelle
0.32EC:3.4.22 GO:0004197
sp|Q86WQ0|NR2CA_HUMAN
Nuclear receptor 2C2-associated protein
Search
NR2C2AP
0.97Nuclear receptor 2C2-associated protein isoform B
0.40GO:0006367transcription initiation from RNA polymerase II promoter
0.37GO:0007155cell adhesion
0.34GO:0042254ribosome biogenesis
0.34GO:0006396RNA processing
0.39GO:0005540hyaluronic acid binding
0.36GO:0005515protein binding
0.34GO:0016746transferase activity, transferring acyl groups
0.68GO:0005654nucleoplasm
0.42GO:0070062extracellular exosome
0.35GO:0005730nucleolus
0.34EC:2.3 GO:0016746
sp|Q86WR0|CCD25_HUMAN
Coiled-coil domain-containing protein 25
Search
CCDC25
0.90Coiled-coil domain-containing protein 25
0.42GO:0043043peptide biosynthetic process
0.40GO:0044267cellular protein metabolic process
0.39GO:0010467gene expression
0.39GO:0009059macromolecule biosynthetic process
0.46GO:0005515protein binding
0.43GO:0003735structural constituent of ribosome
0.65GO:0070062extracellular exosome
0.42GO:0005840ribosome
sp|Q86WR6|CQ064_HUMAN
Uncharacterized protein C17orf64
Search
sp|Q86WR7|PRSR2_HUMAN
Proline and serine-rich protein 2
Search
PROSER2
0.97Proline and serine-rich protein 2
0.58GO:0005515protein binding
sp|Q86WS3|OOSP2_HUMAN
Oocyte-secreted protein 2
Search
OOSP2
0.97Oocyte-secreted protein 2
0.66GO:0005576extracellular region
sp|Q86WS4|CL040_HUMAN
Uncharacterized protein C12orf40
Search
sp|Q86WS5|TMPSC_HUMAN
Transmembrane protease serine 12
Search
TMPRSS12
0.82Brain-specific serine protease 4
0.61GO:0006508proteolysis
0.44GO:0006898receptor-mediated endocytosis
0.36GO:0007340acrosome reaction
0.35GO:0007596blood coagulation
0.35GO:0051604protein maturation
0.35GO:0006887exocytosis
0.34GO:0044256protein digestion
0.34GO:0007190activation of adenylate cyclase activity
0.34GO:0016310phosphorylation
0.34GO:0019800peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.69GO:0004252serine-type endopeptidase activity
0.47GO:0005044scavenger receptor activity
0.34GO:0016301kinase activity
0.34GO:0005537mannose binding
0.34GO:0005509calcium ion binding
0.33GO:0008201heparin binding
0.32GO:0005515protein binding
0.40GO:0001669acrosomal vesicle
0.36GO:0043083synaptic cleft
0.36GO:0043195terminal bouton
0.35GO:0030425dendrite
0.34GO:0005903brush border
0.33GO:0044437vacuolar part
0.33GO:0044433cytoplasmic vesicle part
0.33GO:0005886plasma membrane
0.33GO:0005578proteinaceous extracellular matrix
0.33GO:0005615extracellular space
0.69EC:3.4.21 GO:0004252
sp|Q86WT1|TT30A_HUMAN
Tetratricopeptide repeat protein 30A
Search
0.45Phosphodiesterase
0.81GO:0042073intraciliary transport
0.76GO:0060271cilium assembly
0.60GO:0036372opsin transport
0.59GO:0018095protein polyglutamylation
0.56GO:0001736establishment of planar polarity
0.55GO:0007368determination of left/right symmetry
0.37GO:0007165signal transduction
0.62GO:0070738tubulin-glycine ligase activity
0.44GO:0005215transporter activity
0.41GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity
0.36GO:0005515protein binding
0.36GO:0046872metal ion binding
0.77GO:0030992intraciliary transport particle B
0.74GO:0005929cilium
0.58GO:0005881cytoplasmic microtubule
0.57GO:0032838plasma membrane bounded cell projection cytoplasm
0.44GO:0005815microtubule organizing center
0.30GO:0016020membrane
0.62EC:6.3.2 GO:0070738
sp|Q86WT6|TRI69_HUMAN
E3 ubiquitin-protein ligase TRIM69
Search
TRIM69
0.95Tripartite motif-containing protein 69
0.58GO:0016567protein ubiquitination
0.41GO:0006915apoptotic process
0.38GO:2000059negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.37GO:2001235positive regulation of apoptotic signaling pathway
0.34GO:0032526response to retinoic acid
0.34GO:0007275multicellular organism development
0.32GO:0010508positive regulation of autophagy
0.32GO:0009405pathogenesis
0.58GO:0004842ubiquitin-protein transferase activity
0.52GO:0046872metal ion binding
0.42GO:0016874ligase activity
0.36GO:0005515protein binding
0.33GO:0003723RNA binding
0.32GO:0090729toxin activity
0.62GO:0016607nuclear speck
0.42GO:0005737cytoplasm
0.34GO:0005694chromosome
0.32GO:0005576extracellular region
0.30GO:0031224intrinsic component of membrane
0.42EC:6 GO:0016874
0.58KEGG:R03876 GO:0004842
sp|Q86WU2|LDHD_HUMAN
Probable D-lactate dehydrogenase, mitochondrial
Search
LDHD
0.66Lactate dehydrogenase D
0.53GO:0055114oxidation-reduction process
0.66GO:0050660flavin adenine dinucleotide binding
0.65GO:0016614oxidoreductase activity, acting on CH-OH group of donors
0.52GO:0005739mitochondrion
0.35GO:0019866organelle inner membrane
0.65EC:1.1 GO:0016614
sp|Q86WV1|SKAP1_HUMAN
Src kinase-associated phosphoprotein 1
Search
SKAP1
0.95Src kinase-associated phosphoprotein 1
0.62GO:0002757immune response-activating signal transduction
0.58GO:0002768immune response-regulating cell surface receptor signaling pathway
0.57GO:0072659protein localization to plasma membrane
0.54GO:0045785positive regulation of cell adhesion
0.54GO:0048522positive regulation of cellular process
0.52GO:0010557positive regulation of macromolecule biosynthetic process
0.52GO:0010628positive regulation of gene expression
0.52GO:0051173positive regulation of nitrogen compound metabolic process
0.51GO:0006357regulation of transcription by RNA polymerase II
0.50GO:0023056positive regulation of signaling
0.61GO:0042169SH2 domain binding
0.58GO:0019903protein phosphatase binding
0.56GO:0019901protein kinase binding
0.55GO:0005070SH3/SH2 adaptor activity
0.51GO:0016301kinase activity
0.39GO:0032403protein complex binding
0.36GO:0017124SH3 domain binding
0.34GO:0043565sequence-specific DNA binding
0.60GO:0042101T cell receptor complex
0.54GO:0005829cytosol
0.54GO:0005911cell-cell junction
0.50GO:0005634nucleus
0.43GO:0043233organelle lumen
0.40GO:0044446intracellular organelle part
0.30GO:0016021integral component of membrane
sp|Q86WV5|TEN1L_HUMAN
CST complex subunit TEN1
Search
TEN1
0.97CST complex subunit TEN1
0.47GO:0032211negative regulation of telomere maintenance via telomerase
0.40GO:0016233telomere capping
0.74GO:0003697single-stranded DNA binding
0.45GO:0042162telomeric DNA binding
0.36GO:0005515protein binding
0.85GO:1990879CST complex
sp|Q86WV6|STING_HUMAN
Stimulator of interferon genes protein
Search
TMEM173
0.97Stimulator of interferon genes
0.85GO:0032481positive regulation of type I interferon production
0.82GO:0002218activation of innate immune response
0.66GO:0032608interferon-beta production
0.63GO:0033160positive regulation of protein import into nucleus, translocation
0.63GO:0002230positive regulation of defense response to virus by host
0.62GO:0071360cellular response to exogenous dsRNA
0.61GO:0042993positive regulation of transcription factor import into nucleus
0.60GO:0032092positive regulation of protein binding
0.59GO:0035458cellular response to interferon-beta
0.57GO:0051607defense response to virus
0.76GO:0035438cyclic-di-GMP binding
0.67GO:0061507cyclic-GMP-AMP binding
0.56GO:0019901protein kinase binding
0.55GO:0042803protein homodimerization activity
0.54GO:0031625ubiquitin protein ligase binding
0.53GO:0008134transcription factor binding
0.56GO:0005741mitochondrial outer membrane
0.55GO:0048471perinuclear region of cytoplasm
0.53GO:0005789endoplasmic reticulum membrane
0.53GO:0042579microbody
0.50GO:0005794Golgi apparatus
0.37GO:0030667secretory granule membrane
0.36GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q86WW8|COA5_HUMAN
Cytochrome c oxidase assembly factor 5
Search
COA5
0.91Mitochondrial cytochrome c oxidase assembly factor 5
0.65GO:0033617mitochondrial respiratory chain complex IV assembly
0.39GO:0006487protein N-linked glycosylation
0.36GO:0005975carbohydrate metabolic process
0.33GO:2001141regulation of RNA biosynthetic process
0.33GO:2000112regulation of cellular macromolecule biosynthetic process
0.33GO:0010468regulation of gene expression
0.39GO:0008375acetylglucosaminyltransferase activity
0.36GO:0005515protein binding
0.34GO:0043565sequence-specific DNA binding
0.34GO:0008270zinc ion binding
0.34GO:0003700DNA binding transcription factor activity
0.60GO:0005739mitochondrion
0.36GO:0031970organelle envelope lumen
0.36GO:1905369endopeptidase complex
0.36GO:0031301integral component of organelle membrane
0.34GO:0043234protein complex
0.34GO:0019866organelle inner membrane
0.39EC:2.4.1 GO:0008375
sp|Q86WX3|AROS_HUMAN
Active regulator of SIRT1
Search
RPS19BP1
0.95Active regulator of SIRT1
0.70GO:0019899enzyme binding
0.43GO:0003723RNA binding
0.73GO:0005730nucleolus
0.70GO:0005654nucleoplasm
0.67GO:0005829cytosol
sp|Q86WZ0|HEAT4_HUMAN
HEAT repeat-containing protein 4
Search
HEATR4
0.97LOW QUALITY PROTEIN: HEAT repeat-containing protein 4
sp|Q86WZ6|ZN227_HUMAN
Zinc finger protein 227
Search
0.65Zinc finger protein 227
0.54GO:1903506regulation of nucleic acid-templated transcription
0.54GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.36GO:0010467gene expression
0.36GO:0097659nucleic acid-templated transcription
0.36GO:0034645cellular macromolecule biosynthetic process
0.34GO:0043043peptide biosynthetic process
0.34GO:0044267cellular protein metabolic process
0.33GO:1902679negative regulation of RNA biosynthetic process
0.51GO:0003676nucleic acid binding
0.51GO:0046872metal ion binding
0.45GO:0003700DNA binding transcription factor activity
0.35GO:0003735structural constituent of ribosome
0.30GO:0005515protein binding
0.43GO:0005622intracellular
0.37GO:0031974membrane-enclosed lumen
0.37GO:0043227membrane-bounded organelle
0.35GO:0044422organelle part
0.34GO:1990904ribonucleoprotein complex
0.34GO:0043228non-membrane-bounded organelle
sp|Q86X02|CDR2L_HUMAN
Cerebellar degeneration-related protein 2-like
Search
CDR2L
0.97Cerebellar degeneration related protein 2 like
0.55GO:0006415translational termination
0.55GO:0003747translation release factor activity
0.46GO:0005515protein binding
0.36GO:0005737cytoplasm
sp|Q86X10|RLGPB_HUMAN
Ral GTPase-activating protein subunit beta
Search
RALGAPB
0.92Ral GTPase activating protein non-catalytic beta subunit
0.75GO:0051056regulation of small GTPase mediated signal transduction
0.75GO:0043547positive regulation of GTPase activity
0.38GO:0032484Ral protein signal transduction
0.37GO:0060178regulation of exocyst localization
0.75GO:0005096GTPase activator activity
0.51GO:0046982protein heterodimerization activity
0.33GO:0005829cytosol
sp|Q86X19|TMM17_HUMAN
Transmembrane protein 17
Search
TMEM17
0.97Transmembrane protein 17
0.57GO:1905515non-motile cilium assembly
0.55GO:0007224smoothened signaling pathway
0.33GO:0005515protein binding
0.32GO:0003676nucleic acid binding
0.57GO:0036038MKS complex
0.57GO:0060170ciliary membrane
0.30GO:0031224intrinsic component of membrane
sp|Q86X24|HORM1_HUMAN
HORMA domain-containing protein 1
Search
HORMAD1
0.94LOW QUALITY PROTEIN: HORMA domain-containing protein 2
0.85GO:0051177meiotic sister chromatid cohesion
0.82GO:0060629regulation of homologous chromosome segregation
0.80GO:0051598meiotic recombination checkpoint
0.78GO:0042138meiotic DNA double-strand break formation
0.77GO:0007130synaptonemal complex assembly
0.74GO:0001824blastocyst development
0.73GO:0048477oogenesis
0.72GO:0007283spermatogenesis
0.36GO:0005515protein binding
0.82GO:0000795synaptonemal complex
0.34GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q86X27|RGPS2_HUMAN
Ras-specific guanine nucleotide-releasing factor RalGPS2
Search
RALGPS2
0.92Ras-specific guanine nucleotide-releasing factor RalGPS2
0.86GO:0032485regulation of Ral protein signal transduction
0.76GO:0007264small GTPase mediated signal transduction
0.66GO:0065009regulation of molecular function
0.75GO:0005085guanyl-nucleotide exchange factor activity
0.45GO:0005622intracellular
0.34GO:0005886plasma membrane
sp|Q86X29|LSR_HUMAN
Lipolysis-stimulated lipoprotein receptor
Search
LSR
0.94Lipolysis-stimulated lipoprotein receptor
0.64GO:1904274tricellular tight junction assembly
0.63GO:0061833protein localization to tricellular tight junction
0.61GO:0060856establishment of blood-brain barrier
0.58GO:0001889liver development
0.49GO:0031016pancreas development
0.47GO:0048873homeostasis of number of cells within a tissue
0.47GO:0030073insulin secretion
0.46GO:0009749response to glucose
0.42GO:0007492endoderm development
0.40GO:0019216regulation of lipid metabolic process
0.38GO:0017129triglyceride binding
0.37GO:0030169low-density lipoprotein particle binding
0.37GO:0030228lipoprotein particle receptor activity
0.37GO:0005504fatty acid binding
0.36GO:0005515protein binding
0.61GO:0061689tricellular tight junction
0.43GO:0005886plasma membrane
0.43GO:0034362low-density lipoprotein particle
0.42GO:0042627chylomicron
0.42GO:0034361very-low-density lipoprotein particle
0.39GO:0070062extracellular exosome
0.34GO:0005789endoplasmic reticulum membrane
0.30GO:0016021integral component of membrane
sp|Q86X40|LRC28_HUMAN
Leucine-rich repeat-containing protein 28
Search
LRRC28
0.97Leucine-rich repeat-containing protein 28
0.61GO:0007165signal transduction
0.56GO:0005886plasma membrane
sp|Q86X45|TILB_HUMAN
Protein tilB homolog
Search
LRRC6
0.97Leucine-rich repeat-containing protein 6
0.86GO:0060287epithelial cilium movement involved in determination of left/right asymmetry
0.85GO:0036158outer dynein arm assembly
0.85GO:0036159inner dynein arm assembly
0.84GO:0044458motile cilium assembly
0.83GO:0030317flagellated sperm motility
0.83GO:0008584male gonad development
0.37GO:0005515protein binding
0.34GO:0030246carbohydrate binding
0.76GO:0005929cilium
0.49GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q86X51|CX067_HUMAN
Uncharacterized protein CXorf67
Search
sp|Q86X52|CHSS1_HUMAN
Chondroitin sulfate synthase 1
Search
CHSY1
0.55Chondroitin sulfate synthase 1
0.57GO:0050650chondroitin sulfate proteoglycan biosynthetic process
0.55GO:0051216cartilage development
0.54GO:0030204chondroitin sulfate metabolic process
0.53GO:0030279negative regulation of ossification
0.53GO:0045880positive regulation of smoothened signaling pathway
0.52GO:0009954proximal/distal pattern formation
0.52GO:0009887animal organ morphogenesis
0.51GO:0060348bone development
0.51GO:0051923sulfation
0.48GO:0048468cell development
0.85GO:0008376acetylgalactosaminyltransferase activity
0.40GO:0050510N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
0.36GO:0008378galactosyltransferase activity
0.34GO:0046872metal ion binding
0.34GO:0004252serine-type endopeptidase activity
0.81GO:0032580Golgi cisterna membrane
0.45GO:0005576extracellular region
0.36GO:0030176integral component of endoplasmic reticulum membrane
0.85EC:2.4.1 GO:0008376
sp|Q86X53|ERIC1_HUMAN
Glutamate-rich protein 1
Search
ERICH1
0.76Glutamate-rich protein 1
sp|Q86X55|CARM1_HUMAN
Histone-arginine methyltransferase CARM1
Search
CARM1
0.94Coactivator-associated arginine methyltransferase 1-a
0.73GO:0008213protein alkylation
0.67GO:0043414macromolecule methylation
0.63GO:0003420regulation of growth plate cartilage chondrocyte proliferation
0.60GO:0030520intracellular estrogen receptor signaling pathway
0.59GO:0033146regulation of intracellular estrogen receptor signaling pathway
0.59GO:0071168protein localization to chromatin
0.59GO:0045595regulation of cell differentiation
0.58GO:0060350endochondral bone morphogenesis
0.58GO:0018195peptidyl-arginine modification
0.58GO:0032091negative regulation of protein binding
0.64GO:0035642histone methyltransferase activity (H3-R17 specific)
0.62GO:0035242protein-arginine omega-N asymmetric methyltransferase activity
0.58GO:0001105RNA polymerase II transcription coactivator activity
0.58GO:0030374ligand-dependent nuclear receptor transcription coactivator activity
0.58GO:0070577lysine-acetylated histone binding
0.53GO:0044212transcription regulatory region DNA binding
0.53GO:0042803protein homodimerization activity
0.53GO:0090575RNA polymerase II transcription factor complex
0.51GO:0005829cytosol
0.51GO:0005654nucleoplasm
0.30GO:0016021integral component of membrane
sp|Q86X59|CQ082_HUMAN
Putative uncharacterized protein C17orf82
Search
sp|Q86X60|FA72B_HUMAN
Protein FAM72B
Search
0.61GO:0031551regulation of brain-derived neurotrophic factor-activated receptor activity
0.59GO:0031549negative regulation of brain-derived neurotrophic factor receptor signaling pathway
0.55GO:0061099negative regulation of protein tyrosine kinase activity
0.55GO:2000272negative regulation of receptor activity
0.53GO:0090288negative regulation of cellular response to growth factor stimulus
0.51GO:0043065positive regulation of apoptotic process
0.41GO:0005515protein binding
0.38GO:0019706protein-cysteine S-palmitoyltransferase activity
0.62GO:0005829cytosol
0.53GO:0043231intracellular membrane-bounded organelle
0.30GO:0016020membrane
0.38EC:2.3.1.225 GO:0019706
sp|Q86X67|NUD13_HUMAN
Nucleoside diphosphate-linked moiety X motif 13
Search
NUDT13
0.97Nucleoside diphosphate-linked moiety X motif 13
0.36GO:0015949nucleobase-containing small molecule interconversion
0.52GO:0046872metal ion binding
0.51GO:0016787hydrolase activity
0.39GO:0005739mitochondrion
0.34GO:0070013intracellular organelle lumen
0.33GO:0044446intracellular organelle part
0.51EC:3 GO:0016787
sp|Q86X76|NIT1_HUMAN
Nitrilase homolog 1
Search
NIT1
0.56Deaminated glutathione amidase
0.45GO:0006807nitrogen compound metabolic process
0.36GO:1901837negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.36GO:0046697decidualization
0.36GO:0008625extrinsic apoptotic signaling pathway via death domain receptors
0.35GO:0042177negative regulation of protein catabolic process
0.35GO:0046686response to cadmium ion
0.33GO:0046434organophosphate catabolic process
0.32GO:0046700heterocycle catabolic process
0.32GO:1901361organic cyclic compound catabolic process
0.32GO:0019439aromatic compound catabolic process
0.37GO:0016787hydrolase activity
0.34GO:0016746transferase activity, transferring acyl groups
0.33GO:0003676nucleic acid binding
0.32GO:0046872metal ion binding
0.43GO:0005739mitochondrion
0.37GO:0070062extracellular exosome
0.36GO:0005634nucleus
0.34GO:0031974membrane-enclosed lumen
0.33GO:0009536plastid
0.33GO:0043232intracellular non-membrane-bounded organelle
0.33GO:0044446intracellular organelle part
0.33GO:0005829cytosol
0.37EC:3 GO:0016787
sp|Q86X83|COMD2_HUMAN
COMM domain-containing protein 2
Search
COMMD2
0.97COMM domain-containing protein 2
0.52GO:0097659nucleic acid-templated transcription
0.51GO:1903506regulation of nucleic acid-templated transcription
0.51GO:2000112regulation of cellular macromolecule biosynthetic process
0.51GO:0010468regulation of gene expression
0.49GO:0010467gene expression
0.48GO:0034645cellular macromolecule biosynthetic process
0.40GO:0009072aromatic amino acid family metabolic process
0.45GO:0005515protein binding
0.44GO:0004334fumarylacetoacetase activity
0.45GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
0.44EC:3.7.1.2 GO:0004334
0.44KEGG:R01364 GO:0004334
sp|Q86X95|CIR1_HUMAN
Corepressor interacting with RBPJ 1
Search
CIR1
0.87Corepressor interacting with RBPJ 1
0.71GO:0045892negative regulation of transcription, DNA-templated
0.47GO:0008380RNA splicing
0.45GO:0006397mRNA processing
0.42GO:0006357regulation of transcription by RNA polymerase II
0.41GO:0006351transcription, DNA-templated
0.38GO:0045893positive regulation of transcription, DNA-templated
0.35GO:0022900electron transport chain
0.77GO:0019901protein kinase binding
0.42GO:0003705transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.41GO:0003714transcription corepressor activity
0.40GO:0042826histone deacetylase binding
0.35GO:0020037heme binding
0.35GO:0009055electron transfer activity
0.35GO:0046872metal ion binding
0.35GO:0046982protein heterodimerization activity
0.33GO:0003676nucleic acid binding
0.81GO:0000118histone deacetylase complex
0.79GO:0016607nuclear speck
0.77GO:0005813centrosome
0.59GO:0043234protein complex
0.37GO:0005737cytoplasm
sp|Q86XA0|MET23_HUMAN
Methyltransferase-like protein 23
Search
METTL23
0.90Major facilitator superfamily domain containing 11
0.58GO:0032259methylation
0.56GO:0050890cognition
0.53GO:0045944positive regulation of transcription by RNA polymerase II
0.34GO:0018205peptidyl-lysine modification
0.34GO:0008213protein alkylation
0.59GO:0008168methyltransferase activity
0.54GO:0031072heat shock protein binding
0.52GO:0008134transcription factor binding
0.36GO:0000062fatty-acyl-CoA binding
0.33GO:0003723RNA binding
0.33GO:0140096catalytic activity, acting on a protein
0.46GO:0005634nucleus
0.45GO:0043234protein complex
0.40GO:0005737cytoplasm
0.30GO:0016020membrane
0.59EC:2.1.1 GO:0008168
sp|Q86XA9|HTR5A_HUMAN
HEAT repeat-containing protein 5A
Search
HEATR5A
0.87HEAT repeat-containing protein 5A
0.46GO:0043043peptide biosynthetic process
0.44GO:0044267cellular protein metabolic process
0.43GO:0010467gene expression
0.42GO:0009059macromolecule biosynthetic process
0.48GO:0003735structural constituent of ribosome
0.47GO:0070062extracellular exosome
0.47GO:0005840ribosome
0.30GO:0031224intrinsic component of membrane
sp|Q86XD5|F131B_HUMAN
Protein FAM131B
Search
sp|Q86XD8|ZFAN4_HUMAN
AN1-type zinc finger protein 4
Search
ZFAND4
0.97AN1-type zinc finger and ubiquitin domain-containing protein 1
0.63GO:0008270zinc ion binding
0.30GO:0044425membrane part
sp|Q86XE0|SNX32_HUMAN
Sorting nexin-32
Search
SNX6
0.75Sorting nexin
0.63GO:0015031protein transport
0.62GO:0046907intracellular transport
0.62GO:0034613cellular protein localization
0.49GO:0016050vesicle organization
0.46GO:0006897endocytosis
0.37GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway
0.37GO:1903593regulation of histamine secretion by mast cell
0.37GO:0016241regulation of macroautophagy
0.36GO:0045892negative regulation of transcription, DNA-templated
0.35GO:0007175negative regulation of epidermal growth factor-activated receptor activity
0.75GO:0035091phosphatidylinositol binding
0.44GO:0034713type I transforming growth factor beta receptor binding
0.39GO:0034452dynactin binding
0.36GO:0042803protein homodimerization activity
0.34GO:0046982protein heterodimerization activity
0.34GO:0003779actin binding
0.50GO:0005768endosome
0.47GO:0019898extrinsic component of membrane
0.43GO:0005764lysosome
0.38GO:0030904retromer complex
0.37GO:0044433cytoplasmic vesicle part
0.37GO:0098805whole membrane
0.36GO:0098588bounding membrane of organelle
0.36GO:0005829cytosol
0.34GO:0005634nucleus
0.34GO:0015629actin cytoskeleton
sp|Q86XE3|MICU3_HUMAN
Calcium uptake protein 3, mitochondrial
Search
MICU3
0.92Calcium uptake protein 3, mitochondrial
0.38GO:0006851mitochondrial calcium ion transmembrane transport
0.70GO:0005509calcium ion binding
0.36GO:0005739mitochondrion
0.35GO:0019866organelle inner membrane
0.30GO:0031224intrinsic component of membrane
sp|Q86XE5|HOGA1_HUMAN
4-hydroxy-2-oxoglutarate aldolase, mitochondrial
Search
HOGA1
0.58N-acetylneuraminate lyase
0.60GO:00194704-hydroxyproline catabolic process
0.55GO:0009436glyoxylate catabolic process
0.54GO:0042866pyruvate biosynthetic process
0.54GO:0033609oxalate metabolic process
0.33GO:0015711organic anion transport
0.32GO:0055085transmembrane transport
0.61GO:0016829lyase activity
0.50GO:0042803protein homodimerization activity
0.33GO:0008514organic anion transmembrane transporter activity
0.45GO:0005739mitochondrion
0.37GO:0070062extracellular exosome
0.34GO:0031974membrane-enclosed lumen
0.33GO:0044446intracellular organelle part
0.33GO:0005887integral component of plasma membrane
0.61EC:4 GO:0016829
sp|Q86XF0|DYR2_HUMAN
Dihydrofolate reductase 2, mitochondrial
Search
DHFR
0.43Viral dihydrofolate reductase
0.74GO:0046654tetrahydrofolate biosynthetic process
0.52GO:0055114oxidation-reduction process
0.48GO:0031427response to methotrexate
0.47GO:0046146tetrahydrobiopterin metabolic process
0.47GO:0034312diol biosynthetic process
0.47GO:0051000positive regulation of nitric-oxide synthase activity
0.47GO:2000121regulation of removal of superoxide radicals
0.46GO:0046452dihydrofolate metabolic process
0.45GO:0003232bulbus arteriosus development
0.45GO:0046655folic acid metabolic process
0.78GO:0004146dihydrofolate reductase activity
0.47GO:0051870methotrexate binding
0.46GO:0003729mRNA binding
0.46GO:0000900translation repressor activity, nucleic acid binding
0.44GO:0005542folic acid binding
0.43GO:0070402NADPH binding
0.42GO:0051871dihydrofolic acid binding
0.37GO:0033560folate reductase activity
0.34GO:0016757transferase activity, transferring glycosyl groups
0.34GO:0004386helicase activity
0.43GO:0005739mitochondrion
0.36GO:0031974membrane-enclosed lumen
0.36GO:0005829cytosol
0.35GO:0019866organelle inner membrane
0.30GO:0016021integral component of membrane
0.78EC:1.5.1.3 GO:0004146
sp|Q86XF7|ZN575_HUMAN
Zinc finger protein 575
Search
ZNF575
0.83Zinc finger protein 575
0.45GO:1903506regulation of nucleic acid-templated transcription
0.45GO:2000112regulation of cellular macromolecule biosynthetic process
0.44GO:0010468regulation of gene expression
0.35GO:0070941eisosome assembly
0.32GO:0006351transcription, DNA-templated
0.51GO:0003676nucleic acid binding
0.44GO:0046872metal ion binding
0.37GO:0003700DNA binding transcription factor activity
0.41GO:0005634nucleus
0.35GO:0032126eisosome
0.35GO:0005876spindle microtubule
0.32GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q86XG9|NBPF5_HUMAN
Putative neuroblastoma breakpoint family member 5
Search
0.88Neuroblastoma breakpoint family member 9
0.49GO:1903955positive regulation of protein targeting to mitochondrion
0.36GO:0007616long-term memory
0.40GO:0005509calcium ion binding
0.37GO:0003723RNA binding
0.48GO:0005737cytoplasm
sp|Q86XH1|IQCA1_HUMAN
IQ and AAA domain-containing protein 1
Search
IQCA1
0.93IQ motif-containing with AAA domain
0.34GO:0016567protein ubiquitination
0.34GO:0035556intracellular signal transduction
0.54GO:0030554adenyl nucleotide binding
0.53GO:0097367carbohydrate derivative binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0005622intracellular
sp|Q86XI2|CNDG2_HUMAN
Condensin-2 complex subunit G2
Search
NCAPG2
0.95Non-SMC condensin II complex subunit G2
0.57GO:0001833inner cell mass cell proliferation
0.38GO:0030261chromosome condensation
0.36GO:0051301cell division
0.36GO:0007049cell cycle
0.59GO:0140034methylation-dependent protein binding
0.57GO:0042393histone binding
0.36GO:0043425bHLH transcription factor binding
0.61GO:0005634nucleus
0.56GO:0000796condensin complex
0.50GO:0070013intracellular organelle lumen
0.30GO:0031224intrinsic component of membrane
sp|Q86XI6|PPR3B_HUMAN
Protein phosphatase 1 regulatory subunit 3B
Search
PPP1R3B
0.88Protein phosphatase 1 regulatory subunit
0.84GO:0005981regulation of glycogen catabolic process
0.77GO:0043666regulation of phosphoprotein phosphatase activity
0.71GO:0005977glycogen metabolic process
0.39GO:0005979regulation of glycogen biosynthetic process
0.37GO:0006470protein dephosphorylation
0.37GO:0009250glucan biosynthetic process
0.79GO:0019888protein phosphatase regulator activity
0.39GO:0019899enzyme binding
0.37GO:0004721phosphoprotein phosphatase activity
0.78GO:0000164protein phosphatase type 1 complex
0.40GO:0042587glycogen granule
0.34GO:0043231intracellular membrane-bounded organelle
0.37EC:3.1.3.16 GO:0004721
sp|Q86XI8|CS068_HUMAN
Uncharacterized protein C19orf68
Search
sp|Q86XJ0|CAHM3_HUMAN
Calcium homeostasis modulator protein 3
Search
CALHM3
0.96Calcium homeostasis modulator protein 3
0.53GO:0050917sensory perception of umami taste
0.52GO:0050916sensory perception of sweet taste
0.51GO:0098655cation transmembrane transport
0.51GO:0050913sensory perception of bitter taste
0.50GO:0015867ATP transport
0.48GO:0051260protein homooligomerization
0.48GO:0034765regulation of ion transmembrane transport
0.47GO:0006816calcium ion transport
0.42GO:0098660inorganic ion transmembrane transport
0.62GO:0005227calcium activated cation channel activity
0.57GO:0022832voltage-gated channel activity
0.48GO:0005262calcium channel activity
0.46GO:0042802identical protein binding
0.48GO:0005887integral component of plasma membrane
0.34GO:0005789endoplasmic reticulum membrane
sp|Q86XJ1|GA2L3_HUMAN
GAS2-like protein 3
Search
GAS2L3
0.97Growth arrest-specific 2 like 3
0.67GO:0000226microtubule cytoskeleton organization
0.65GO:0030036actin cytoskeleton organization
0.57GO:0006915apoptotic process
0.40GO:0021923cell proliferation in hindbrain ventricular zone
0.39GO:0021591ventricular system development
0.36GO:0007050cell cycle arrest
0.34GO:0008360regulation of cell shape
0.74GO:0008017microtubule binding
0.65GO:0003779actin binding
0.68GO:0005856cytoskeleton
0.37GO:0099512supramolecular fiber
0.35GO:0044446intracellular organelle part
0.35GO:0043234protein complex
0.33GO:0005829cytosol
0.30GO:0016020membrane
sp|Q86XK2|FBX11_HUMAN
F-box only protein 11
Search
FBXO11
0.74F-box only protein 11
0.73GO:0016567protein ubiquitination
0.51GO:0035246peptidyl-arginine N-methylation
0.50GO:0007605sensory perception of sound
0.39GO:0043687post-translational protein modification
0.38GO:0006511ubiquitin-dependent protein catabolic process
0.32GO:0006351transcription, DNA-templated
0.32GO:0006355regulation of transcription, DNA-templated
0.61GO:0008270zinc ion binding
0.52GO:0016274protein-arginine N-methyltransferase activity
0.47GO:0004842ubiquitin-protein transferase activity
0.38GO:0005515protein binding
0.32GO:0003677DNA binding
0.76GO:0000151ubiquitin ligase complex
0.47GO:0005730nucleolus
0.45GO:0005829cytosol
0.39GO:0005694chromosome
0.52EC:2.1.1 GO:0016274
0.47KEGG:R03876 GO:0004842
sp|Q86XK3|SFR1_HUMAN
Swi5-dependent recombination DNA repair protein 1 homolog
Search
SFR1
0.97Swi5-dependent recombination DNA repair protein 1
0.85GO:0071391cellular response to estrogen stimulus
0.76GO:0000724double-strand break repair via homologous recombination
0.72GO:0045893positive regulation of transcription, DNA-templated
0.41GO:0006351transcription, DNA-templated
0.84GO:0030374ligand-dependent nuclear receptor transcription coactivator activity
0.38GO:0005515protein binding
0.87GO:0032798Swi5-Sfr1 complex
0.30GO:0031224intrinsic component of membrane
sp|Q86XK7|VSIG1_HUMAN
V-set and immunoglobulin domain-containing protein 1
Search
VSIG1
0.97V-set and immunoglobulin domain-containing protein 1
0.85GO:0030277maintenance of gastrointestinal epithelium
0.85GO:0003382epithelial cell morphogenesis
0.36GO:0048565digestive tract development
0.32GO:0006508proteolysis
0.32GO:0017171serine hydrolase activity
0.32GO:0070011peptidase activity, acting on L-amino acid peptides
0.55GO:0005886plasma membrane
0.36GO:0005881cytoplasmic microtubule
0.35GO:0005923bicellular tight junction
0.30GO:0016021integral component of membrane
sp|Q86XL3|ANKL2_HUMAN
Ankyrin repeat and LEM domain-containing protein 2
Search
ANKLE2
0.96Ankyrin repeat and LEM domain-containing protein 2
0.85GO:0007084mitotic nuclear envelope reassembly
0.84GO:0035307positive regulation of protein dephosphorylation
0.53GO:0007417central nervous system development
0.53GO:0043066negative regulation of apoptotic process
0.52GO:0042326negative regulation of phosphorylation
0.37GO:0051301cell division
0.36GO:0043666regulation of phosphoprotein phosphatase activity
0.85GO:0051721protein phosphatase 2A binding
0.36GO:0019888protein phosphatase regulator activity
0.53GO:0030176integral component of endoplasmic reticulum membrane
sp|Q86XM0|CTSRD_HUMAN
Cation channel sperm-associated protein subunit delta
Search
CATSPERD
0.97Cation channel sperm associated auxiliary subunit delta
0.55GO:0048240sperm capacitation
0.54GO:0030317flagellated sperm motility
0.47GO:0007275multicellular organism development
0.44GO:0032570response to progesterone
0.43GO:0035036sperm-egg recognition
0.38GO:0005515protein binding
0.85GO:0036128CatSper complex
0.55GO:0097228sperm principal piece
sp|Q86XN6|ZN761_HUMAN
Zinc finger protein 761
Search
0.60Zinc finger protein 845
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.57GO:1903506regulation of nucleic acid-templated transcription
0.56GO:0010468regulation of gene expression
0.51GO:0003676nucleic acid binding
0.51GO:0046872metal ion binding
0.40GO:0003700DNA binding transcription factor activity
0.46GO:0001650fibrillar center
0.42GO:0015630microtubule cytoskeleton
sp|Q86XN7|PRSR1_HUMAN
Proline and serine-rich protein 1
Search
PROSER1
0.97LOW QUALITY PROTEIN: proline and serine-rich protein 1
sp|Q86XN8|MEX3D_HUMAN
RNA-binding protein MEX3D
Search
MEX3D
0.80Mex-3 RNA binding family member D
0.42GO:0003415chondrocyte hypertrophy
0.41GO:0097009energy homeostasis
0.40GO:0045598regulation of fat cell differentiation
0.59GO:0003723RNA binding
0.52GO:0048471perinuclear region of cytoplasm
0.47GO:0005634nucleus
0.42GO:0005829cytosol
0.42GO:0031974membrane-enclosed lumen
0.39GO:0044446intracellular organelle part
sp|Q86XP0|PA24D_HUMAN
Cytosolic phospholipase A2 delta
Search
0.66Cytosolic phospholipase A2 epsilon
0.80GO:0009395phospholipid catabolic process
0.57GO:0046503glycerolipid catabolic process
0.51GO:0006650glycerophospholipid metabolic process
0.37GO:0097164ammonium ion metabolic process
0.36GO:0006575cellular modified amino acid metabolic process
0.36GO:0045017glycerolipid biosynthetic process
0.35GO:0008654phospholipid biosynthetic process
0.34GO:0036498IRE1-mediated unfolded protein response
0.34GO:0007567parturition
0.34GO:0019369arachidonic acid metabolic process
0.83GO:0102568phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.83GO:0102567phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.80GO:0004623phospholipase A2 activity
0.53GO:0046872metal ion binding
0.40GO:0004622lysophospholipase activity
0.39GO:0008970phosphatidylcholine 1-acylhydrolase activity
0.34GO:0005544calcium-dependent phospholipid binding
0.48GO:0005737cytoplasm
0.35GO:0098805whole membrane
0.35GO:0098588bounding membrane of organelle
0.34GO:0097708intracellular vesicle
0.34GO:0044446intracellular organelle part
0.33GO:0043231intracellular membrane-bounded organelle
0.33GO:0012506vesicle membrane
0.33GO:0012505endomembrane system
0.33GO:0005576extracellular region
0.32GO:0031975envelope
0.80EC:3.1.1.4 GO:0004623
sp|Q86XP1|DGKH_HUMAN
Diacylglycerol kinase eta
Search
DGKH
0.48Diacylglycerol kinase eta
0.83GO:0007205protein kinase C-activating G-protein coupled receptor signaling pathway
0.62GO:0035556intracellular signal transduction
0.57GO:0016310phosphorylation
0.53GO:0046473phosphatidic acid metabolic process
0.51GO:0051259protein oligomerization
0.39GO:0010033response to organic substance
0.38GO:0046339diacylglycerol metabolic process
0.35GO:0030168platelet activation
0.32GO:0006508proteolysis
0.80GO:0004143diacylglycerol kinase activity
0.75GO:0003951NAD+ kinase activity
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0042803protein homodimerization activity
0.51GO:0046982protein heterodimerization activity
0.33GO:0046872metal ion binding
0.32GO:0004252serine-type endopeptidase activity
0.50GO:0005768endosome
0.38GO:0005829cytosol
0.36GO:0005886plasma membrane
0.32GO:0005576extracellular region
0.30GO:0016021integral component of membrane
0.80EC:2.7.1.107 GO:0004143
0.75KEGG:R00104 GO:0003951
sp|Q86XP3|DDX42_HUMAN
ATP-dependent RNA helicase DDX42
Search
DDX42
0.96DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
0.63GO:0042981regulation of apoptotic process
0.56GO:0008104protein localization
0.53GO:0010501RNA secondary structure unwinding
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.53GO:0004386helicase activity
0.51GO:0003676nucleic acid binding
0.50GO:0008186RNA-dependent ATPase activity
0.44GO:0140098catalytic activity, acting on RNA
0.67GO:0016607nuclear speck
0.58GO:0005829cytosol
0.49GO:0005730nucleolus
0.30GO:0016020membrane
sp|Q86XP6|GKN2_HUMAN
Gastrokine-2
Search
GKN2
0.97Gastrokine-2
0.58GO:0042127regulation of cell proliferation
0.85GO:0045178basal part of cell
0.56GO:0005615extracellular space
0.38GO:0005794Golgi apparatus
0.30GO:0044425membrane part
sp|Q86XQ3|CTSR3_HUMAN
Cation channel sperm-associated protein 3
Search
CATSPER3
0.97Cation channel sperm-associated protein 3 transcript variant 1
0.72GO:0048240sperm capacitation
0.70GO:0006816calcium ion transport
0.70GO:0030317flagellated sperm motility
0.60GO:0006814sodium ion transport
0.60GO:0034220ion transmembrane transport
0.57GO:0086010membrane depolarization during action potential
0.40GO:0034765regulation of ion transmembrane transport
0.40GO:0032570response to progesterone
0.40GO:0035036sperm-egg recognition
0.39GO:0071804cellular potassium ion transport
0.74GO:0005245voltage-gated calcium channel activity
0.40GO:0005249voltage-gated potassium channel activity
0.35GO:0005515protein binding
0.74GO:0005891voltage-gated calcium channel complex
0.69GO:0001669acrosomal vesicle
0.59GO:0005783endoplasmic reticulum
0.41GO:0031514motile cilium
0.40GO:0008076voltage-gated potassium channel complex
sp|Q86XR2|NIBL2_HUMAN
Niban-like protein 2
Search
FAM129C
0.97Niban-like protein 2
sp|Q86XR5|PRIMA_HUMAN
Proline-rich membrane anchor 1
Search
PRIMA1
0.97Proline rich membrane anchor 1
0.39GO:0042135neurotransmitter catabolic process
0.36GO:0051649establishment of localization in cell
0.33GO:0006508proteolysis
0.32GO:0007015actin filament organization
0.32GO:0016192vesicle-mediated transport
0.32GO:0007049cell cycle
0.39GO:0043495protein membrane anchor
0.37GO:0019899enzyme binding
0.32GO:0003779actin binding
0.32GO:0004222metalloendopeptidase activity
0.32GO:0003924GTPase activity
0.32GO:0032550purine ribonucleoside binding
0.32GO:0019001guanyl nucleotide binding
0.32GO:0003677DNA binding
0.31GO:0032555purine ribonucleotide binding
0.31GO:0035639purine ribonucleoside triphosphate binding
0.39GO:0045202synapse
0.39GO:0030054cell junction
0.36GO:0031226intrinsic component of plasma membrane
0.33GO:0005576extracellular region
0.33GO:0005802trans-Golgi network
0.32GO:0031982vesicle
0.30GO:0016021integral component of membrane
0.32EC:3.4.24 GO:0004222
sp|Q86XR7|TCAM2_HUMAN
TIR domain-containing adapter molecule 2
Search
TICAM2
0.97TIR domain-containing adapter molecule 2
0.70GO:2000494positive regulation of interleukin-18-mediated signaling pathway
0.68GO:0035669TRAM-dependent toll-like receptor 4 signaling pathway
0.66GO:0071651positive regulation of chemokine (C-C motif) ligand 5 production
0.66GO:0034145positive regulation of toll-like receptor 4 signaling pathway
0.66GO:0070671response to interleukin-12
0.63GO:0032729positive regulation of interferon-gamma production
0.62GO:0032755positive regulation of interleukin-6 production
0.62GO:0071222cellular response to lipopolysaccharide
0.57GO:0051607defense response to virus
0.45GO:0071650negative regulation of chemokine (C-C motif) ligand 5 production
0.56GO:0005543phospholipid binding
0.37GO:0004871signal transducer activity
0.37GO:0005149interleukin-1 receptor binding
0.36GO:0046982protein heterodimerization activity
0.56GO:0005768endosome
0.45GO:0005886plasma membrane
0.41GO:0005783endoplasmic reticulum
0.40GO:0005794Golgi apparatus
0.38GO:0030667secretory granule membrane
0.36GO:0043235receptor complex
0.30GO:0016021integral component of membrane
sp|Q86XR8|CEP57_HUMAN
Centrosomal protein of 57 kDa
Search
CEP57
0.87Centrosomal protein of isoform A
0.83GO:0034453microtubule anchoring
0.60GO:0000060protein import into nucleus, translocation
0.59GO:0008543fibroblast growth factor receptor signaling pathway
0.57GO:0007286spermatid development
0.55GO:0051260protein homooligomerization
0.48GO:0000070mitotic sister chromatid segregation
0.37GO:0097711ciliary basal body-plasma membrane docking
0.36GO:0000086G2/M transition of mitotic cell cycle
0.36GO:0010389regulation of G2/M transition of mitotic cell cycle
0.80GO:0043015gamma-tubulin binding
0.72GO:0042802identical protein binding
0.72GO:0008017microtubule binding
0.61GO:0017134fibroblast growth factor binding
0.51GO:0046983protein dimerization activity
0.57GO:0005813centrosome
0.54GO:0005874microtubule
0.52GO:0005794Golgi apparatus
0.46GO:0005634nucleus
0.35GO:0005829cytosol
sp|Q86XS5|ANGL5_HUMAN
Angiopoietin-related protein 5
Search
ANGPTL5
0.97Angiopoietin like 5
0.50GO:0032501multicellular organismal process
0.48GO:0007599hemostasis
0.48GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
0.48GO:0042060wound healing
0.47GO:0001775cell activation
0.47GO:0051258protein polymerization
0.46GO:0009653anatomical structure morphogenesis
0.45GO:0043066negative regulation of apoptotic process
0.44GO:0010519negative regulation of phospholipase activity
0.44GO:0051005negative regulation of lipoprotein lipase activity
0.58GO:0005515protein binding
0.48GO:0060090molecular adaptor activity
0.44GO:0005044scavenger receptor activity
0.43GO:0004859phospholipase inhibitor activity
0.41GO:0030545receptor regulator activity
0.40GO:0044877macromolecular complex binding
0.34GO:0003676nucleic acid binding
0.63GO:0005576extracellular region
0.42GO:0005769early endosome
0.41GO:0009986cell surface
0.40GO:0043234protein complex
0.40GO:0005794Golgi apparatus
0.30GO:0016020membrane
sp|Q86XS8|GOLI_HUMAN
E3 ubiquitin-protein ligase RNF130
Search
RNF130
0.91Ring finger protein 130
0.50GO:0012501programmed cell death
0.48GO:0016567protein ubiquitination
0.35GO:0048010vascular endothelial growth factor receptor signaling pathway
0.35GO:0038084vascular endothelial growth factor signaling pathway
0.34GO:0018108peptidyl-tyrosine phosphorylation
0.34GO:0007264small GTPase mediated signal transduction
0.33GO:0065009regulation of molecular function
0.49GO:0004842ubiquitin-protein transferase activity
0.49GO:0016874ligase activity
0.35GO:0005509calcium ion binding
0.35GO:0005021vascular endothelial growth factor-activated receptor activity
0.34GO:0005085guanyl-nucleotide exchange factor activity
0.32GO:0032555purine ribonucleotide binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0030554adenyl nucleotide binding
0.32GO:0008144drug binding
0.32GO:0003924GTPase activity
0.38GO:0005737cytoplasm
0.33GO:0005887integral component of plasma membrane
0.49EC:6 GO:0016874
0.49KEGG:R03876 GO:0004842
sp|Q86XT2|VP37D_HUMAN
Vacuolar protein sorting-associated protein 37D
Search
VPS37D
0.97VPS37D, ESCRT-I subunit
0.82GO:0032509endosome transport via multivesicular body sorting pathway
0.65GO:0015031protein transport
0.83GO:0000813ESCRT I complex
sp|Q86XT4|TRI50_HUMAN
E3 ubiquitin-protein ligase TRIM50
Search
TRIM50
0.97Tripartite motif containing 50
0.55GO:0070201regulation of establishment of protein localization
0.40GO:0061930regulation of erythrocyte enucleation
0.40GO:1902838regulation of nuclear migration along microtubule
0.39GO:0016567protein ubiquitination
0.39GO:1903431positive regulation of cell maturation
0.39GO:0045648positive regulation of erythrocyte differentiation
0.38GO:0035372protein localization to microtubule
0.37GO:0051130positive regulation of cellular component organization
0.37GO:0006511ubiquitin-dependent protein catabolic process
0.36GO:0032874positive regulation of stress-activated MAPK cascade
0.61GO:0008270zinc ion binding
0.46GO:0016874ligase activity
0.41GO:0042802identical protein binding
0.40GO:0004842ubiquitin-protein transferase activity
0.39GO:0045504dynein heavy chain binding
0.39GO:0045505dynein intermediate chain binding
0.37GO:0061659ubiquitin-like protein ligase activity
0.37GO:0051219phosphoprotein binding
0.36GO:0031625ubiquitin protein ligase binding
0.36GO:0008017microtubule binding
0.59GO:0016235aggresome
0.40GO:0005829cytosol
0.36GO:0005881cytoplasmic microtubule
0.32GO:0005634nucleus
0.32GO:0005886plasma membrane
0.32GO:0070013intracellular organelle lumen
0.30GO:0016021integral component of membrane
0.46EC:6 GO:0016874
0.40KEGG:R03876 GO:0004842
sp|Q86XT9|TM219_HUMAN
Insulin-like growth factor-binding protein 3 receptor
Search
TMEM219
0.91Insulin-like growth factor-binding protein 3 receptor
0.51GO:0006915apoptotic process
0.42GO:0042981regulation of apoptotic process
0.41GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q86XU0|ZN677_HUMAN
Zinc finger protein 677
Search
0.64Zinc finger protein 546
0.55GO:1903506regulation of nucleic acid-templated transcription
0.55GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.39GO:0060669embryonic placenta morphogenesis
0.38GO:0006351transcription, DNA-templated
0.36GO:1902679negative regulation of RNA biosynthetic process
0.51GO:0003676nucleic acid binding
0.51GO:0046872metal ion binding
0.44GO:0003700DNA binding transcription factor activity
0.44GO:0005622intracellular
0.38GO:0043227membrane-bounded organelle
sp|Q86XW9|TXND6_HUMAN
Thioredoxin domain-containing protein 6
Search
NME9
0.26LOW QUALITY PROTEIN: thioredoxin domain-containing protein 6
0.75GO:0006228UTP biosynthetic process
0.75GO:0006183GTP biosynthetic process
0.71GO:0046036CTP metabolic process
0.67GO:0006165nucleoside diphosphate phosphorylation
0.66GO:0045454cell redox homeostasis
0.35GO:0030317flagellated sperm motility
0.35GO:0060271cilium assembly
0.34GO:0034614cellular response to reactive oxygen species
0.33GO:0007155cell adhesion
0.32GO:0090305nucleic acid phosphodiester bond hydrolysis
0.75GO:0004550nucleoside diphosphate kinase activity
0.36GO:0032559adenyl ribonucleotide binding
0.36GO:0008144drug binding
0.36GO:0035639purine ribonucleoside triphosphate binding
0.34GO:0008017microtubule binding
0.34GO:0046872metal ion binding
0.33GO:0030246carbohydrate binding
0.32GO:0004519endonuclease activity
0.36GO:0097598sperm cytoplasmic droplet
0.36GO:0005856cytoskeleton
0.36GO:0097228sperm principal piece
0.35GO:0097014ciliary plasm
0.33GO:1902494catalytic complex
0.33GO:0043234protein complex
0.33GO:0044446intracellular organelle part
0.32GO:0005739mitochondrion
0.30GO:0016021integral component of membrane
0.75EC:2.7.4.6 GO:0004550
sp|Q86XX4|FRAS1_HUMAN
Extracellular matrix protein FRAS1
Search
FRAS1
0.93Fraser extracellular matrix complex subunit 1
0.74GO:0003338metanephros morphogenesis
0.72GO:0060021palate development
0.71GO:0030326embryonic limb morphogenesis
0.70GO:0043588skin development
0.67GO:0002009morphogenesis of an epithelium
0.60GO:0007154cell communication
0.56GO:0015031protein transport
0.40GO:0033334fin morphogenesis
0.40GO:0071711basement membrane organization
0.40GO:0010669epithelial structure maintenance
0.81GO:0005604basement membrane
0.30GO:0044425membrane part
sp|Q86XZ4|SPAS2_HUMAN
Spermatogenesis-associated serine-rich protein 2
Search
SPATS2
0.97LOW QUALITY PROTEIN: spermatogenesis-associated serine-rich protein 2
0.38GO:0023014signal transduction by protein phosphorylation
0.37GO:0000160phosphorelay signal transduction system
0.34GO:0034765regulation of ion transmembrane transport
0.34GO:0071805potassium ion transmembrane transport
0.39GO:0003723RNA binding
0.38GO:0000155phosphorelay sensor kinase activity
0.34GO:0005249voltage-gated potassium channel activity
0.67GO:0005829cytosol
0.46GO:0005730nucleolus
0.40GO:0043234protein complex
0.30GO:0016020membrane
0.38EC:2.7.3 GO:0000155
sp|Q86Y01|DTX1_HUMAN
E3 ubiquitin-protein ligase DTX1
Search
0.97Deltex E3 ubiquitin ligase 1
0.54GO:0045581negative regulation of T cell differentiation
0.53GO:0008593regulation of Notch signaling pathway
0.53GO:0045665negative regulation of neuron differentiation
0.53GO:0007219Notch signaling pathway
0.52GO:1990823response to leukemia inhibitory factor
0.52GO:0010001glial cell differentiation
0.50GO:0071345cellular response to cytokine stimulus
0.39GO:0016567protein ubiquitination
0.35GO:0006366transcription by RNA polymerase II
0.35GO:0032479regulation of type I interferon production
0.61GO:0008270zinc ion binding
0.54GO:0005112Notch binding
0.51GO:0031625ubiquitin protein ligase binding
0.43GO:0016874ligase activity
0.37GO:0017124SH3 domain binding
0.35GO:0003713transcription coactivator activity
0.34GO:0016740transferase activity
0.33GO:0140096catalytic activity, acting on a protein
0.50GO:0016604nuclear body
0.47GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
0.43EC:6 GO:0016874
sp|Q86Y07|VRK2_HUMAN
Serine/threonine-protein kinase VRK2
Search
VRK2
0.93Vaccinia related kinase
0.70GO:2000659regulation of interleukin-1-mediated signaling pathway
0.64GO:0046777protein autophosphorylation
0.60GO:0043408regulation of MAPK cascade
0.58GO:0034599cellular response to oxidative stress
0.54GO:0018105peptidyl-serine phosphorylation
0.47GO:0008360regulation of cell shape
0.41GO:0072355histone H3-T3 phosphorylation
0.41GO:0090166Golgi disassembly
0.64GO:0004672protein kinase activity
0.61GO:0019901protein kinase binding
0.59GO:0019904protein domain specific binding
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.40GO:0031493nucleosomal histone binding
0.56GO:0005789endoplasmic reticulum membrane
0.53GO:0005634nucleus
0.50GO:0031966mitochondrial membrane
0.49GO:0043234protein complex
0.39GO:0005795Golgi stack
0.37GO:0005829cytosol
0.37GO:0031974membrane-enclosed lumen
0.35GO:0043232intracellular non-membrane-bounded organelle
0.30GO:0016021integral component of membrane
sp|Q86Y13|DZIP3_HUMAN
E3 ubiquitin-protein ligase DZIP3
Search
DZIP3
0.90DAZ interacting zinc finger protein 3
0.82GO:0000209protein polyubiquitination
0.57GO:0030968endoplasmic reticulum unfolded protein response
0.56GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.56GO:0030433ubiquitin-dependent ERAD pathway
0.76GO:0061630ubiquitin protein ligase activity
0.74GO:0031593polyubiquitin modification-dependent protein binding
0.72GO:0019902phosphatase binding
0.60GO:1990381ubiquitin-specific protease binding
0.59GO:0003723RNA binding
0.51GO:0051082unfolded protein binding
0.37GO:0016874ligase activity
0.34GO:0008270zinc ion binding
0.60GO:0044322endoplasmic reticulum quality control compartment
0.59GO:0036513Derlin-1 retrotranslocation complex
0.58GO:0000836Hrd1p ubiquitin ligase complex
0.30GO:0016021integral component of membrane
0.37EC:6 GO:0016874
sp|Q86Y22|CONA1_HUMAN
Collagen alpha-1(XXIII) chain
Search
COL23A1
0.95Collagen type XXIII alpha 1 chain
0.46GO:0060385axonogenesis involved in innervation
0.39GO:0070207protein homotrimerization
0.35GO:0030574collagen catabolic process
0.46GO:0008201heparin binding
0.45GO:0001540amyloid-beta binding
0.37GO:0042803protein homodimerization activity
0.35GO:0008483transaminase activity
0.35GO:0030170pyridoxal phosphate binding
0.35GO:0005201extracellular matrix structural constituent
0.73GO:0005581collagen trimer
0.43GO:0005615extracellular space
0.40GO:0005887integral component of plasma membrane
0.37GO:0009986cell surface
0.36GO:0005788endoplasmic reticulum lumen
0.35GO:0005604basement membrane
0.35EC:2.6.1 GO:0008483
sp|Q86Y25|Z354C_HUMAN
Zinc finger protein 354C
Search
ZNF879
0.42Zinc finger and SCAN domain containing 2
0.54GO:1903506regulation of nucleic acid-templated transcription
0.54GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.43GO:0006351transcription, DNA-templated
0.34GO:0007219Notch signaling pathway
0.34GO:1902679negative regulation of RNA biosynthetic process
0.33GO:0007186G-protein coupled receptor signaling pathway
0.51GO:0003676nucleic acid binding
0.51GO:0046872metal ion binding
0.49GO:0003700DNA binding transcription factor activity
0.34GO:0003682chromatin binding
0.33GO:0004930G-protein coupled receptor activity
0.47GO:0005634nucleus
0.40GO:0005829cytosol
0.39GO:0012505endomembrane system
0.38GO:0031967organelle envelope
0.37GO:0031090organelle membrane
0.34GO:0031974membrane-enclosed lumen
0.32GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q86Y26|NUTM1_HUMAN
NUT family member 1
Search
NUTM1
0.97NUT midline carcinoma family member 1
0.57GO:0005515protein binding
0.60GO:0005634nucleus
0.48GO:0005737cytoplasm
sp|Q86Y27|BAGE5_HUMAN
B melanoma antigen 5
Search
0.94B melanoma antigen 5
0.66GO:0005576extracellular region
sp|Q86Y28|BAGE4_HUMAN
B melanoma antigen 4
Search
0.94B melanoma antigen 4
0.66GO:0005576extracellular region
sp|Q86Y29|BAGE3_HUMAN
B melanoma antigen 3
Search
0.89B melanoma antigen 3
0.66GO:0005576extracellular region
sp|Q86Y30|BAGE2_HUMAN
B melanoma antigen 2
Search
0.89B melanoma antigen 2
0.66GO:0005576extracellular region
sp|Q86Y33|CD20B_HUMAN
Cell division cycle protein 20 homolog B
Search
CDC20B
0.94Cell division cycle protein 20 like protein B
0.83GO:1904668positive regulation of ubiquitin protein ligase activity
0.68GO:0031145anaphase-promoting complex-dependent catabolic process
0.54GO:0051301cell division
0.50GO:0031915positive regulation of synaptic plasticity
0.50GO:0090129positive regulation of synapse maturation
0.48GO:0000070mitotic sister chromatid segregation
0.47GO:0040020regulation of meiotic nuclear division
0.47GO:0090307mitotic spindle assembly
0.45GO:0007062sister chromatid cohesion
0.38GO:0070727cellular macromolecule localization
0.84GO:0097027ubiquitin-protein transferase activator activity
0.84GO:0010997anaphase-promoting complex binding
0.48GO:0008022protein C-terminus binding
0.44GO:0019899enzyme binding
0.36GO:0004896cytokine receptor activity
0.34GO:0009922fatty acid elongase activity
0.48GO:0005680anaphase-promoting complex
0.44GO:0005654nucleoplasm
0.43GO:0005829cytosol
0.42GO:0033597mitotic checkpoint complex
0.36GO:0000922spindle pole
0.36GO:0005815microtubule organizing center
0.36GO:0048471perinuclear region of cytoplasm
0.34GO:0034399nuclear periphery
0.33GO:0005783endoplasmic reticulum
0.30GO:0016020membrane
sp|Q86Y34|AGRG3_HUMAN
Adhesion G protein-coupled receptor G3
Search
ADGRG3
0.91Adhesion G protein-coupled receptor G3
0.67GO:0007166cell surface receptor signaling pathway
0.67GO:0007186G-protein coupled receptor signaling pathway
0.67GO:0032792negative regulation of CREB transcription factor activity
0.66GO:1901223negative regulation of NIK/NF-kappaB signaling
0.62GO:0030183B cell differentiation
0.59GO:0030334regulation of cell migration
0.39GO:0043312neutrophil degranulation
0.34GO:0060347heart trabecula formation
0.34GO:0022011myelination in peripheral nervous system
0.34GO:0019933cAMP-mediated signaling
0.68GO:0004930G-protein coupled receptor activity
0.34GO:0043236laminin binding
0.48GO:0005886plasma membrane
0.44GO:0005829cytosol
0.39GO:0035579specific granule membrane
0.36GO:0045177apical part of cell
0.35GO:0070062extracellular exosome
0.35GO:0009986cell surface
0.30GO:0031224intrinsic component of membrane
sp|Q86Y37|CACL1_HUMAN
CDK2-associated and cullin domain-containing protein 1
Search
CACUL1
0.97CDK2-associated and cullin domain-containing protein 1
0.71GO:0006511ubiquitin-dependent protein catabolic process
0.61GO:0000082G1/S transition of mitotic cell cycle
0.59GO:0008284positive regulation of cell proliferation
0.58GO:0045860positive regulation of protein kinase activity
0.46GO:0016567protein ubiquitination
0.77GO:0031625ubiquitin protein ligase binding
0.58GO:0019901protein kinase binding
0.48GO:0061630ubiquitin protein ligase activity
0.48GO:0031461cullin-RING ubiquitin ligase complex
sp|Q86Y38|XYLT1_HUMAN
Xylosyltransferase 1
Search
XYLT1
0.91Xylosyltransferase I
0.68GO:0006024glycosaminoglycan biosynthetic process
0.47GO:0030166proteoglycan biosynthetic process
0.45GO:0030201heparan sulfate proteoglycan metabolic process
0.45GO:0050654chondroitin sulfate proteoglycan metabolic process
0.45GO:1903510mucopolysaccharide metabolic process
0.40GO:0044272sulfur compound biosynthetic process
0.39GO:0048701embryonic cranial skeleton morphogenesis
0.37GO:0043436oxoacid metabolic process
0.37GO:0034605cellular response to heat
0.35GO:0048681negative regulation of axon regeneration
0.85GO:0030158protein xylosyltransferase activity
0.75GO:0008375acetylglucosaminyltransferase activity
0.48GO:0000139Golgi membrane
0.40GO:0005789endoplasmic reticulum membrane
0.34GO:0005576extracellular region
0.30GO:0016021integral component of membrane
0.85EC:2.4.2.26 GO:0030158
sp|Q86Y39|NDUAB_HUMAN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Search
NDUFA11
0.40NADH dehydrogenase
0.50GO:0032981mitochondrial respiratory chain complex I assembly
0.38GO:0055114oxidation-reduction process
0.35GO:0006119oxidative phosphorylation
0.33GO:0055085transmembrane transport
0.33GO:0022857transmembrane transporter activity
0.56GO:0005747mitochondrial respiratory chain complex I
0.30GO:0016021integral component of membrane
sp|Q86Y46|K2C73_HUMAN
Keratin, type II cytoskeletal 73
Search
0.96Keratin, type II cytoskeletal 73
0.56GO:0045104intermediate filament cytoskeleton organization
0.51GO:0031069hair follicle morphogenesis
0.46GO:0097435supramolecular fiber organization
0.40GO:0030855epithelial cell differentiation
0.38GO:0012501programmed cell death
0.36GO:0050680negative regulation of epithelial cell proliferation
0.62GO:0005198structural molecule activity
0.48GO:1990254keratin filament binding
0.83GO:0045095keratin filament
0.41GO:0070062extracellular exosome
0.37GO:0005737cytoplasm
0.35GO:0009986cell surface
0.34GO:0005634nucleus
sp|Q86Y56|DAAF5_HUMAN
Dynein assembly factor 5, axonemal
Search
DNAAF5
0.94Dynein axonemal assembly factor 5
0.86GO:0036158outer dynein arm assembly
0.85GO:0036159inner dynein arm assembly
0.83GO:0003341cilium movement
0.85GO:0045505dynein intermediate chain binding
0.49GO:0005737cytoplasm
0.49GO:0031514motile cilium
0.30GO:0031224intrinsic component of membrane
sp|Q86Y78|LYPD6_HUMAN
Ly6/PLAUR domain-containing protein 6
Search
LYPD6
0.97Ly6/PLAUR domain-containing protein 6
0.78GO:0099601regulation of neurotransmitter receptor activity
0.73GO:2000272negative regulation of receptor activity
0.55GO:0060827regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
0.53GO:2000053regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
0.53GO:0060061Spemann organizer formation
0.50GO:0090263positive regulation of canonical Wnt signaling pathway
0.35GO:0006501C-terminal protein lipidation
0.32GO:0006508proteolysis
0.81GO:0030548acetylcholine receptor regulator activity
0.73GO:0030547receptor inhibitor activity
0.36GO:0005515protein binding
0.34GO:0004198calcium-dependent cysteine-type endopeptidase activity
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0031225anchored component of membrane
0.44GO:0031226intrinsic component of plasma membrane
0.43GO:0045121membrane raft
0.41GO:0043005neuron projection
0.41GO:0045202synapse
0.41GO:0030054cell junction
0.39GO:0005576extracellular region
0.35GO:0005737cytoplasm
0.30GO:0016021integral component of membrane
sp|Q86Y79|PTH_HUMAN
Probable peptidyl-tRNA hydrolase
Search
PTRH1
0.47Peptidyl-tRNA hydrolase
0.40GO:0043043peptide biosynthetic process
0.39GO:0044267cellular protein metabolic process
0.38GO:0010467gene expression
0.38GO:0009059macromolecule biosynthetic process
0.32GO:0032259methylation
0.32GO:0036211protein modification process
0.79GO:0004045aminoacyl-tRNA hydrolase activity
0.35GO:0003723RNA binding
0.34GO:0005515protein binding
0.32GO:0008168methyltransferase activity
0.32GO:0140096catalytic activity, acting on a protein
0.47GO:0005739mitochondrion
0.79EC:3.1.1.29 GO:0004045
sp|Q86Y82|STX12_HUMAN
Syntaxin-12
Search
STX12
0.91Protein phosphatase 1 regulatory subunit 8
0.69GO:0016192vesicle-mediated transport
0.68GO:0006886intracellular protein transport
0.68GO:0061025membrane fusion
0.56GO:0033344cholesterol efflux
0.54GO:0000045autophagosome assembly
0.52GO:0050821protein stabilization
0.47GO:0048284organelle fusion
0.47GO:0016050vesicle organization
0.47GO:0140056organelle localization by membrane tethering
0.40GO:1902685positive regulation of receptor localization to synapse
0.80GO:0005484SNAP receptor activity
0.49GO:0000149SNARE binding
0.39GO:0019869chloride channel inhibitor activity
0.56GO:0031201SNARE complex
0.55GO:0031083BLOC-1 complex
0.54GO:0030139endocytic vesicle
0.54GO:0000407phagophore assembly site
0.53GO:0045121membrane raft
0.44GO:0012505endomembrane system
0.39GO:0005766primary lysosome
0.39GO:0001772immunological synapse
0.39GO:0099503secretory vesicle
0.38GO:0044433cytoplasmic vesicle part
sp|Q86Y91|KI18B_HUMAN
Kinesin-like protein KIF18B
Search
0.18Kinesin family member 18B
0.74GO:0007018microtubule-based movement
0.75GO:0003777microtubule motor activity
0.70GO:0008017microtubule binding
0.53GO:0030554adenyl nucleotide binding
0.52GO:0097367carbohydrate derivative binding
0.52GO:0008144drug binding
0.52GO:0035639purine ribonucleoside triphosphate binding
0.69GO:1990752microtubule end
0.63GO:0016604nuclear body
0.57GO:0005829cytosol
sp|Q86Y97|KMT5C_HUMAN
Histone-lysine N-methyltransferase KMT5C
Search
KMT5C
0.45Histone-lysine N-methyltransferase
0.85GO:0034773histone H4-K20 trimethylation
0.42GO:0040014regulation of multicellular organism growth
0.37GO:0006351transcription, DNA-templated
0.36GO:0007517muscle organ development
0.36GO:1903506regulation of nucleic acid-templated transcription
0.36GO:2000112regulation of cellular macromolecule biosynthetic process
0.36GO:0010468regulation of gene expression
0.85GO:0042799histone methyltransferase activity (H4-K20 specific)
0.34GO:0005515protein binding
0.56GO:0005721pericentric heterochromatin
0.56GO:0000780condensed nuclear chromosome, centromeric region
0.56GO:0005720nuclear heterochromatin
0.49GO:0005654nucleoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q86YA3|ZGRF1_HUMAN
Protein ZGRF1
Search
ZGRF1
0.92Zinc finger GRF-type containing 1
0.63GO:0008270zinc ion binding
sp|Q86YB7|ECHD2_HUMAN
Enoyl-CoA hydratase domain-containing protein 2, mitochondrial
Search
ECHDC2
0.95Enoyl-CoA hydratase domain-containing protein 2
0.45GO:0006635fatty acid beta-oxidation
0.36GO:0006574valine catabolic process
0.46GO:0004300enoyl-CoA hydratase activity
0.36GO:00038603-hydroxyisobutyryl-CoA hydrolase activity
0.33GO:00038593-hydroxybutyryl-CoA dehydratase activity
0.33GO:0016853isomerase activity
0.40GO:0005739mitochondrion
0.30GO:0031224intrinsic component of membrane
0.46EC:4.2.1.17 GO:0004300
0.33KEGG:R03027 GO:0003859
sp|Q86YB8|ERO1B_HUMAN
ERO1-like protein beta
Search
ERO1B
0.50Endoplasmic reticulum oxidoreductase 1 beta
0.53GO:0055114oxidation-reduction process
0.51GO:0022417protein maturation by protein folding
0.51GO:00194714-hydroxyproline metabolic process
0.50GO:0030070insulin processing
0.48GO:0034975protein folding in endoplasmic reticulum
0.47GO:0030198extracellular matrix organization
0.47GO:0042593glucose homeostasis
0.43GO:0045454cell redox homeostasis
0.40GO:0036211protein modification process
0.38GO:0044267cellular protein metabolic process
0.83GO:0003756protein disulfide isomerase activity
0.76GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.47GO:0015035protein disulfide oxidoreductase activity
0.34GO:0051082unfolded protein binding
0.70GO:0005783endoplasmic reticulum
0.43GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.42GO:0031984organelle subcompartment
0.30GO:0016021integral component of membrane
0.83EC:5.3.4.1 GO:0003756
sp|Q86YC2|PALB2_HUMAN
Partner and localizer of BRCA2
Search
PALB2
0.93Partner and localizer of BRCA2
0.87GO:0001833inner cell mass cell proliferation
0.86GO:0036342post-anal tail morphogenesis
0.85GO:0001756somitogenesis
0.85GO:0035264multicellular organism growth
0.84GO:0007498mesoderm development
0.80GO:0048568embryonic organ development
0.78GO:0043066negative regulation of apoptotic process
0.77GO:0009887animal organ morphogenesis
0.77GO:0000724double-strand break repair via homologous recombination
0.48GO:0000732strand displacement
0.55GO:0003677DNA binding
0.39GO:0005515protein binding
0.70GO:0005654nucleoplasm
sp|Q86YC3|NRROS_HUMAN
Negative regulator of reactive oxygen species
Search
NRROS
0.97Negative regulator of reactive oxygen species
0.59GO:0006954inflammatory response
0.57GO:0006955immune response
0.56GO:0006801superoxide metabolic process
0.36GO:0030433ubiquitin-dependent ERAD pathway
0.34GO:0006468protein phosphorylation
0.32GO:0051014actin filament severing
0.32GO:0007411axon guidance
0.32GO:0006915apoptotic process
0.32GO:0030036actin cytoskeleton organization
0.32GO:0006470protein dephosphorylation
0.34GO:0004672protein kinase activity
0.34GO:0005515protein binding
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0004721phosphoprotein phosphatase activity
0.32GO:00038563-dehydroquinate synthase activity
0.31GO:0044877macromolecular complex binding
0.31GO:0016491oxidoreductase activity
0.31GO:0043169cation binding
0.54GO:0005783endoplasmic reticulum
0.40GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.39GO:0031984organelle subcompartment
0.36GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
0.32EC:3.1.3.16 GO:0004721
0.32KEGG:R03083 GO:0003856
sp|Q86YD1|PTOV1_HUMAN
Prostate tumor-overexpressed gene 1 protein
Search
PTOV1
0.70Prostate tumor overexpressed 1
0.30GO:0051252regulation of RNA metabolic process
0.30GO:2000112regulation of cellular macromolecule biosynthetic process
0.30GO:0090304nucleic acid metabolic process
0.30GO:0019438aromatic compound biosynthetic process
0.30GO:0044260cellular macromolecule metabolic process
0.30GO:0010467gene expression
0.30GO:0018130heterocycle biosynthetic process
0.30GO:1901576organic substance biosynthetic process
0.30GO:0010468regulation of gene expression
0.30GO:0044271cellular nitrogen compound biosynthetic process
0.61GO:0005634nucleus
0.30GO:0071944cell periphery
0.30GO:0005737cytoplasm
0.30GO:0016020membrane
sp|Q86YD3|TMM25_HUMAN
Transmembrane protein 25
Search
TMEM25
0.97LOW QUALITY PROTEIN: transmembrane protein 25
0.34GO:0005515protein binding
0.37GO:0005576extracellular region
0.35GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q86YD5|LRAD3_HUMAN
Low-density lipoprotein receptor class A domain-containing protein 3
Search
LDLRAD3
0.97Low-density lipoprotein receptor class A domain-containing protein 3
0.59GO:0070613regulation of protein processing
0.52GO:0006898receptor-mediated endocytosis
0.60GO:0001540amyloid-beta binding
0.35GO:0005509calcium ion binding
0.44GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q86YD7|F90A1_HUMAN
Protein FAM90A1
Search
0.45GO:0007186G-protein coupled receptor signaling pathway
0.43GO:0000128flocculation
0.60GO:0005515protein binding
0.49GO:0016503pheromone receptor activity
0.30GO:0044425membrane part
sp|Q86YE8|ZN573_HUMAN
Zinc finger protein 573
Search
0.67Zinc finger protein 28
0.56GO:1903506regulation of nucleic acid-templated transcription
0.56GO:2000112regulation of cellular macromolecule biosynthetic process
0.55GO:0010468regulation of gene expression
0.36GO:0006351transcription, DNA-templated
0.35GO:1902679negative regulation of RNA biosynthetic process
0.34GO:0007275multicellular organism development
0.34GO:1902680positive regulation of RNA biosynthetic process
0.52GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.42GO:0003700DNA binding transcription factor activity
0.34GO:0003682chromatin binding
0.33GO:0005515protein binding
0.44GO:0005622intracellular
0.35GO:0043227membrane-bounded organelle
0.30GO:0016020membrane
sp|Q86YF9|DZIP1_HUMAN
Zinc finger protein DZIP1
Search
DZIP1
0.89DAZ interacting zinc finger protein 1
0.75GO:0051220cytoplasmic sequestering of protein
0.72GO:0007224smoothened signaling pathway
0.71GO:0060271cilium assembly
0.57GO:0045184establishment of protein localization
0.36GO:0032880regulation of protein localization
0.51GO:0003676nucleic acid binding
0.75GO:0097539ciliary transition fiber
0.73GO:0036064ciliary basal body
0.72GO:0005814centriole
0.61GO:0005654nucleoplasm
0.60GO:0005829cytosol
sp|Q86YG4|NT5D4_HUMAN
5'-nucleotidase domain-containing protein 4
Search
NT5C2
0.87Cytosolic purine 5'-nucleotidase
0.46GO:0046085adenosine metabolic process
0.44GO:0016311dephosphorylation
0.41GO:0046040IMP metabolic process
0.38GO:0071466cellular response to xenobiotic stimulus
0.34GO:0006195purine nucleotide catabolic process
0.32GO:0016310phosphorylation
0.53GO:0046872metal ion binding
0.48GO:00082535'-nucleotidase activity
0.35GO:0050146nucleoside phosphotransferase activity
0.34GO:1901265nucleoside phosphate binding
0.34GO:0005515protein binding
0.34GO:0036094small molecule binding
0.33GO:0005737cytoplasm
0.30GO:0016020membrane
0.48EC:3.1.3.5 GO:0008253
sp|Q86YH2|Z280B_HUMAN
Zinc finger protein 280B
Search
0.90Suppressor of hairy wing homolog 2
0.35GO:0097659nucleic acid-templated transcription
0.35GO:1903506regulation of nucleic acid-templated transcription
0.35GO:2000112regulation of cellular macromolecule biosynthetic process
0.35GO:0010468regulation of gene expression
0.34GO:0010467gene expression
0.34GO:0034645cellular macromolecule biosynthetic process
0.51GO:0003676nucleic acid binding
0.34GO:0046872metal ion binding
0.35GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
sp|Q86YH6|DLP1_HUMAN
Decaprenyl-diphosphate synthase subunit 2
Search
PDSS2
0.95Mutant decaprenyl diphosphate synthase subunit 2
0.70GO:0008299isoprenoid biosynthetic process
0.60GO:0051290protein heterotetramerization
0.56GO:0050878regulation of body fluid levels
0.54GO:0006744ubiquinone biosynthetic process
0.63GO:0000010trans-hexaprenyltranstransferase activity
0.62GO:0050347trans-octaprenyltranstransferase activity
0.53GO:0046982protein heterodimerization activity
0.50GO:1990234transferase complex
0.50GO:0005829cytosol
0.46GO:0005739mitochondrion
0.34GO:0031974membrane-enclosed lumen
0.33GO:0044446intracellular organelle part
0.30GO:0044425membrane part
0.62EC:2.5.1.84 EC:2.5.1.85 GO:0050347
0.63KEGG:R05612 GO:0000010
sp|Q86YI8|PHF13_HUMAN
PHD finger protein 13
Search
PHF13
0.96PHD finger protein 13
0.60GO:0007076mitotic chromosome condensation
0.37GO:0016569covalent chromatin modification
0.36GO:0051301cell division
0.36GO:1901097negative regulation of autophagosome maturation
0.36GO:1902902negative regulation of autophagosome assembly
0.35GO:0006914autophagy
0.35GO:0031398positive regulation of protein ubiquitination
0.57GO:0003682chromatin binding
0.53GO:0046872metal ion binding
0.36GO:0140034methylation-dependent protein binding
0.36GO:0042393histone binding
0.32GO:0003677DNA binding
0.48GO:0005634nucleus
0.36GO:0031974membrane-enclosed lumen
0.35GO:0044446intracellular organelle part
0.32GO:0005737cytoplasm
sp|Q86YJ5|MARH9_HUMAN
E3 ubiquitin-protein ligase MARCH9
Search
MARCH9
0.53Membrane-associated RING-CH protein IX
0.47GO:0016567protein ubiquitination
0.63GO:0008270zinc ion binding
0.50GO:0016874ligase activity
0.47GO:0004842ubiquitin-protein transferase activity
0.57GO:0005802trans-Golgi network
0.57GO:0005795Golgi stack
0.38GO:0000139Golgi membrane
0.37GO:0005765lysosomal membrane
0.30GO:0044425membrane part
0.50EC:6 GO:0016874
0.47KEGG:R03876 GO:0004842
sp|Q86YJ6|THNS2_HUMAN
Threonine synthase-like 2
Search
THNSL2
0.97Threonine synthase like 2
0.86GO:00463602-oxobutyrate biosynthetic process
0.72GO:0009071serine family amino acid catabolic process
0.66GO:0016311dephosphorylation
0.57GO:0009088threonine biosynthetic process
0.39GO:0010469regulation of receptor activity
0.38GO:0008345larval locomotory behavior
0.37GO:0007420brain development
0.86GO:0070905serine binding
0.65GO:0070279vitamin B6 binding
0.62GO:0004795threonine synthase activity
0.58GO:0050662coenzyme binding
0.40GO:0005125cytokine activity
0.38GO:0005615extracellular space
0.62EC:4.2.3.1 GO:0004795
sp|Q86YJ7|AN13B_HUMAN
Ankyrin repeat domain-containing protein 13B
Search
ANKRD13B
0.92LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 13B
0.39GO:0006511ubiquitin-dependent protein catabolic process
0.38GO:0035335peptidyl-tyrosine dephosphorylation
0.40GO:0031625ubiquitin protein ligase binding
0.39GO:0008138protein tyrosine/serine/threonine phosphatase activity
0.38GO:0004725protein tyrosine phosphatase activity
0.53GO:0043231intracellular membrane-bounded organelle
0.43GO:0005770late endosome
0.43GO:0005769early endosome
0.37GO:0005886plasma membrane
0.37GO:0031461cullin-RING ubiquitin ligase complex
0.30GO:0031224intrinsic component of membrane
0.39EC:3.1.3 GO:0008138
sp|Q86YL5|TDRP_HUMAN
Testis development-related protein
Search
TDRP
0.97Testis development-related protein variant B
0.80GO:0007283spermatogenesis
0.51GO:0005829cytosol
0.47GO:0005634nucleus
sp|Q86YL7|PDPN_HUMAN
Podoplanin
Search
PDPN
0.97Podoplanin
0.65GO:1901731positive regulation of platelet aggregation
0.65GO:1905863invadopodium organization
0.61GO:0090091positive regulation of extracellular matrix disassembly
0.61GO:2000392regulation of lamellipodium morphogenesis
0.59GO:0090505epiboly involved in wound healing
0.59GO:0010718positive regulation of epithelial to mesenchymal transition
0.58GO:0007266Rho protein signal transduction
0.57GO:0051272positive regulation of cellular component movement
0.55GO:0040017positive regulation of locomotion
0.55GO:0030334regulation of cell migration
0.58GO:0019956chemokine binding
0.53GO:0051087chaperone binding
0.51GO:0005102receptor binding
0.46GO:0008517folic acid transmembrane transporter activity
0.45GO:0015250water channel activity
0.42GO:0015171amino acid transmembrane transporter activity
0.36GO:0004466long-chain-acyl-CoA dehydrogenase activity
0.33GO:0050660flavin adenine dinucleotide binding
0.63GO:0061851leading edge of lamellipodium
0.61GO:0097197tetraspanin-enriched microdomain
0.61GO:0031258lamellipodium membrane
0.60GO:0031528microvillus membrane
0.60GO:0031527filopodium membrane
0.60GO:0071437invadopodium
0.58GO:0001726ruffle
0.56GO:0016323basolateral plasma membrane
0.56GO:0016324apical plasma membrane
0.56GO:0045121membrane raft
0.36EC:1.3.99.13 GO:0004466
sp|Q86YM7|HOME1_HUMAN
Homer protein homolog 1
Search
HOMER1
0.87Homer protein like protein 1
0.81GO:0048875chemical homeostasis within a tissue
0.80GO:0048148behavioral response to cocaine
0.79GO:0003009skeletal muscle contraction
0.78GO:2001256regulation of store-operated calcium entry
0.77GO:0090279regulation of calcium ion import
0.77GO:0048741skeletal muscle fiber development
0.77GO:0051592response to calcium ion
0.76GO:0051928positive regulation of calcium ion transport
0.75GO:2001257regulation of cation channel activity
0.50GO:0006874cellular calcium ion homeostasis
0.77GO:0044325ion channel binding
0.70GO:0035256G-protein coupled glutamate receptor binding
0.40GO:0097110scaffold protein binding
0.39GO:0035591signaling adaptor activity
0.39GO:0032947protein complex scaffold activity
0.38GO:0046982protein heterodimerization activity
0.38GO:0042802identical protein binding
0.80GO:0043034costamere
0.75GO:0030018Z disc
0.75GO:0014069postsynaptic density
0.72GO:0045177apical part of cell
0.72GO:0030424axon
0.51GO:0005886plasma membrane
0.45GO:0030054cell junction
0.40GO:0060076excitatory synapse
0.40GO:0043198dendritic shaft
0.39GO:0005829cytosol
sp|Q86YN1|DOPP1_HUMAN
Dolichyldiphosphatase 1
Search
DOLPP1
0.96Dolichyl pyrophosphate phosphatase 1
0.57GO:0006487protein N-linked glycosylation
0.41GO:0008610lipid biosynthetic process
0.36GO:0046465dolichyl diphosphate metabolic process
0.35GO:0006488dolichol-linked oligosaccharide biosynthetic process
0.35GO:0008053mitochondrial fusion
0.33GO:0090407organophosphate biosynthetic process
0.64GO:0047874dolichyldiphosphatase activity
0.55GO:0030176integral component of endoplasmic reticulum membrane
0.64EC:3.6.1.43 GO:0047874
sp|Q86YN6|PRGC2_HUMAN
Peroxisome proliferator-activated receptor gamma coactivator 1-beta
Search
PPARGC1B
0.97Peroxisome proliferator-activated receptor gamma coactivator 1-beta
0.73GO:0010694positive regulation of alkaline phosphatase activity
0.71GO:0060346bone trabecula formation
0.70GO:0046852positive regulation of bone remodeling
0.70GO:0030520intracellular estrogen receptor signaling pathway
0.69GO:0045672positive regulation of osteoclast differentiation
0.69GO:0045124regulation of bone resorption
0.69GO:0006390mitochondrial transcription
0.65GO:0032846positive regulation of homeostatic process
0.65GO:0001503ossification
0.61GO:0042327positive regulation of phosphorylation
0.86GO:0030331estrogen receptor binding
0.76GO:0003712transcription cofactor activity
0.74GO:0050682AF-2 domain binding
0.63GO:0001076transcription factor activity, RNA polymerase II transcription factor binding
0.58GO:0003723RNA binding
0.34GO:0008270zinc ion binding
0.62GO:0016592mediator complex
0.51GO:0005739mitochondrion
sp|Q86YP4|P66A_HUMAN
Transcriptional repressor p66-alpha
Search
GATAD2A
0.93LOW QUALITY PROTEIN: transcriptional repressor p66-alpha
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.53GO:1902679negative regulation of RNA biosynthetic process
0.37GO:0021995neuropore closure
0.37GO:0001842neural fold formation
0.36GO:0010172embryonic body morphogenesis
0.36GO:0001701in utero embryonic development
0.35GO:0001568blood vessel development
0.35GO:0012501programmed cell death
0.64GO:0043565sequence-specific DNA binding
0.62GO:0008270zinc ion binding
0.61GO:0003700DNA binding transcription factor activity
0.58GO:0030674protein binding, bridging
0.61GO:0016581NuRD complex
0.38GO:0016607nuclear speck
0.30GO:0031224intrinsic component of membrane
sp|Q86YQ2|LATH_HUMAN
Putative BPIFA4P protein
Search
sp|Q86YQ8|CPNE8_HUMAN
Copine-8
Search
CPNE8
0.88Copine VIII
0.58GO:1903861positive regulation of dendrite extension
0.47GO:0000038very long-chain fatty acid metabolic process
0.45GO:0006635fatty acid beta-oxidation
0.38GO:0055085transmembrane transport
0.41GO:0042626ATPase activity, coupled to transmembrane movement of substances
0.38GO:0032559adenyl ribonucleotide binding
0.38GO:0008144drug binding
0.38GO:0035639purine ribonucleoside triphosphate binding
0.58GO:0070062extracellular exosome
0.50GO:0043025neuronal cell body
0.48GO:0043005neuron projection
0.45GO:0005777peroxisome
0.30GO:0016020membrane
sp|Q86YR5|GPSM1_HUMAN
G-protein-signaling modulator 1
Search
0.84G protein signaling modulator 1
0.69GO:0050790regulation of catalytic activity
0.53GO:1905832positive regulation of spindle assembly
0.53GO:1904778positive regulation of protein localization to cell cortex
0.52GO:0051661maintenance of centrosome location
0.52GO:0031291Ran protein signal transduction
0.50GO:0000132establishment of mitotic spindle orientation
0.50GO:0060236regulation of mitotic spindle organization
0.49GO:0007052mitotic spindle organization
0.36GO:0051301cell division
0.35GO:1905098negative regulation of guanyl-nucleotide exchange factor activity
0.76GO:0030695GTPase regulator activity
0.52GO:0001965G-protein alpha-subunit binding
0.50GO:0043621protein self-association
0.50GO:0070840dynein complex binding
0.49GO:0008022protein C-terminus binding
0.47GO:0019904protein domain specific binding
0.46GO:0042802identical protein binding
0.34GO:1901265nucleoside phosphate binding
0.33GO:0036094small molecule binding
0.53GO:0097575lateral cell cortex
0.51GO:0097431mitotic spindle pole
0.48GO:0005813centrosome
0.45GO:0005829cytosol
0.43GO:0005794Golgi apparatus
0.43GO:0005654nucleoplasm
0.41GO:0043234protein complex
0.38GO:0016328lateral plasma membrane
0.34GO:0005789endoplasmic reticulum membrane
0.34GO:0098588bounding membrane of organelle
sp|Q86YR6|POTED_HUMAN
POTE ankyrin domain family member D
Search
0.69POTE ankyrin domain family member D
0.30GO:0071944cell periphery
0.30GO:0016020membrane
sp|Q86YR7|MF2L2_HUMAN
Probable guanine nucleotide exchange factor MCF2L2
Search
0.76Guanine nucleotide exchange factor DBS
0.74GO:0035023regulation of Rho protein signal transduction
0.64GO:0065009regulation of molecular function
0.51GO:0035556intracellular signal transduction
0.32GO:0006954inflammatory response
0.32GO:0006955immune response
0.75GO:0005089Rho guanyl-nucleotide exchange factor activity
0.32GO:0005149interleukin-1 receptor binding
0.32GO:0005125cytokine activity
0.40GO:0005622intracellular
0.32GO:0005615extracellular space
0.30GO:0044425membrane part
sp|Q86YS3|RFIP4_HUMAN
Rab11 family-interacting protein 4
Search
RAB11FIP4
0.97Rab11 family-interacting protein 4
0.71GO:1903452positive regulation of G1 to G0 transition
0.65GO:0003407neural retina development
0.64GO:0032465regulation of cytokinesis
0.44GO:0048592eye morphogenesis
0.39GO:0051301cell division
0.39GO:0007049cell cycle
0.35GO:0016032viral process
0.35GO:2001141regulation of RNA biosynthetic process
0.35GO:2000112regulation of cellular macromolecule biosynthetic process
0.34GO:0010468regulation of gene expression
0.72GO:0030306ADP-ribosylation factor binding
0.66GO:0017137Rab GTPase binding
0.65GO:0005509calcium ion binding
0.62GO:0042803protein homodimerization activity
0.35GO:0003700DNA binding transcription factor activity
0.32GO:0003676nucleic acid binding
0.70GO:0055038recycling endosome membrane
0.69GO:0097610cell surface furrow
0.67GO:0030496midbody
0.66GO:0032155cell division site part
0.66GO:0030139endocytic vesicle
0.61GO:0048471perinuclear region of cytoplasm
0.38GO:0005615extracellular space
0.37GO:0005819spindle
0.37GO:0005815microtubule organizing center
sp|Q86YS6|RAB43_HUMAN
Ras-related protein Rab-43
Search
RAB43
0.93RAB43, member RAS oncogene family
0.57GO:0035526retrograde transport, plasma membrane to Golgi
0.53GO:0090382phagosome maturation
0.52GO:0007030Golgi organization
0.50GO:0071346cellular response to interferon-gamma
0.48GO:1901998toxin transport
0.47GO:0019068virion assembly
0.34GO:0051382kinetochore assembly
0.34GO:0070507regulation of microtubule cytoskeleton organization
0.33GO:0006281DNA repair
0.68GO:0003924GTPase activity
0.66GO:0032550purine ribonucleoside binding
0.66GO:0032561guanyl ribonucleotide binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.36GO:0004767sphingomyelin phosphodiesterase activity
0.34GO:0005515protein binding
0.52GO:0045335phagocytic vesicle
0.49GO:0005794Golgi apparatus
0.43GO:0005768endosome
0.38GO:0030666endocytic vesicle membrane
0.36GO:0070062extracellular exosome
0.34GO:0031984organelle subcompartment
0.34GO:0043025neuronal cell body
0.33GO:0045202synapse
0.33GO:0005874microtubule
0.30GO:0031224intrinsic component of membrane
0.36EC:3.1.4.12 GO:0004767
0.36KEGG:R02541 GO:0004767
sp|Q86YS7|C2CD5_HUMAN
C2 domain-containing protein 5
Search
C2CD5
0.93C2 calcium dependent domain containing 5
0.85GO:0038028insulin receptor signaling pathway via phosphatidylinositol 3-kinase
0.83GO:0090314positive regulation of protein targeting to membrane
0.83GO:0031340positive regulation of vesicle fusion
0.80GO:0010828positive regulation of glucose transport
0.79GO:2001273regulation of glucose import in response to insulin stimulus
0.78GO:1900078positive regulation of cellular response to insulin stimulus
0.74GO:0072659protein localization to plasma membrane
0.73GO:0006906vesicle fusion
0.69GO:0065002intracellular protein transmembrane transport
0.75GO:0005544calcium-dependent phospholipid binding
0.65GO:0005509calcium ion binding
0.80GO:0032587ruffle membrane
0.71GO:0030659cytoplasmic vesicle membrane
0.71GO:0005938cell cortex
0.68GO:0005815microtubule organizing center
0.62GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q86YT5|S13A5_HUMAN
Solute carrier family 13 member 5
Search
SLC13A5
0.96Sodium-dependent citrate transporter
0.73GO:0006814sodium ion transport
0.58GO:0035674tricarboxylic acid transmembrane transport
0.57GO:0071422succinate transmembrane transport
0.55GO:0015746citrate transport
0.34GO:0006357regulation of transcription by RNA polymerase II
0.57GO:0015141succinate transmembrane transporter activity
0.54GO:0015137citrate transmembrane transporter activity
0.48GO:0017153sodium:dicarboxylate symporter activity
0.34GO:0001104RNA polymerase II transcription cofactor activity
0.42GO:0005886plasma membrane
0.34GO:0016592mediator complex
0.30GO:0016021integral component of membrane
sp|Q86YT6|MIB1_HUMAN
E3 ubiquitin-protein ligase MIB1
Search
MIB1
0.90Mindbomb E3 ubiquitin protein ligase 1
0.73GO:0016567protein ubiquitination
0.66GO:0001947heart looping
0.66GO:0001756somitogenesis
0.65GO:0001841neural tube formation
0.65GO:0045807positive regulation of endocytosis
0.65GO:0007219Notch signaling pathway
0.64GO:0045665negative regulation of neuron differentiation
0.62GO:0001568blood vessel development
0.60GO:0001701in utero embryonic development
0.47GO:0006897endocytosis
0.73GO:0004842ubiquitin-protein transferase activity
0.62GO:0008270zinc ion binding
0.48GO:0016874ligase activity
0.62GO:0005813centrosome
0.57GO:0031410cytoplasmic vesicle
0.38GO:0014069postsynaptic density
0.34GO:0030529intracellular ribonucleoprotein complex
0.48EC:6 GO:0016874
0.73KEGG:R03876 GO:0004842
sp|Q86YT9|JAML_HUMAN
Junctional adhesion molecule-like
Search
JAML
0.87Junction adhesion molecule like
0.87GO:0046629gamma-delta T cell activation
0.83GO:0050900leukocyte migration
0.65GO:0060054positive regulation of epithelial cell proliferation involved in wound healing
0.62GO:0007157heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.59GO:0060326cell chemotaxis
0.30GO:0048583regulation of response to stimulus
0.30GO:0002682regulation of immune system process
0.61GO:0005178integrin binding
0.56GO:0042803protein homodimerization activity
0.59GO:0005923bicellular tight junction
0.45GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q86YV0|RASL3_HUMAN
RAS protein activator like-3
Search
RASAL3
0.97RAS protein activator like-3
0.75GO:0043087regulation of GTPase activity
0.75GO:0051140regulation of NK T cell proliferation
0.74GO:0051135positive regulation of NK T cell activation
0.72GO:0046641positive regulation of alpha-beta T cell proliferation
0.72GO:0051345positive regulation of hydrolase activity
0.70GO:0046580negative regulation of Ras protein signal transduction
0.61GO:0007165signal transduction
0.41GO:0030948negative regulation of vascular endothelial growth factor receptor signaling pathway
0.40GO:0016525negative regulation of angiogenesis
0.39GO:0008285negative regulation of cell proliferation
0.74GO:0005096GTPase activator activity
0.39GO:0008745N-acetylmuramoyl-L-alanine amidase activity
0.36GO:0008270zinc ion binding
0.63GO:0098562cytoplasmic side of membrane
0.48GO:0031226intrinsic component of plasma membrane
0.44GO:0005938cell cortex
0.43GO:0070062extracellular exosome
0.37GO:0005829cytosol
0.39EC:3.5.1.28 GO:0008745
sp|Q86YV5|SG223_HUMAN
Tyrosine-protein kinase SgK223
Search
PRAG1
0.89PEAK1 related kinase activating pseudokinase 1
0.63GO:0006468protein phosphorylation
0.64GO:0004672protein kinase activity
0.54GO:0030554adenyl nucleotide binding
0.53GO:0097367carbohydrate derivative binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
sp|Q86YV6|MYLK4_HUMAN
Myosin light chain kinase family member 4
Search
MYLK4
0.94Myosin light chain kinase 3
0.62GO:0006468protein phosphorylation
0.55GO:0002528regulation of vascular permeability involved in acute inflammatory response
0.52GO:0030239myofibril assembly
0.52GO:0071347cellular response to interleukin-1
0.51GO:0018210peptidyl-threonine modification
0.50GO:0018209peptidyl-serine modification
0.45GO:0055013cardiac muscle cell development
0.43GO:0035556intracellular signal transduction
0.38GO:0060298positive regulation of sarcomere organization
0.35GO:0055012ventricular cardiac muscle cell differentiation
0.63GO:0004672protein kinase activity
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.47GO:0015629actin cytoskeleton
0.38GO:0005737cytoplasm
0.37GO:0070062extracellular exosome
0.34GO:0030906retromer, cargo-selective complex
0.30GO:0016021integral component of membrane
sp|Q86YV9|HPS6_HUMAN
Hermansky-Pudlak syndrome 6 protein
Search
HPS6
0.97Hermansky-Pudlak syndrome 6
0.86GO:0030318melanocyte differentiation
0.82GO:0007596blood coagulation
0.80GO:0032418lysosome localization
0.73GO:0072657protein localization to membrane
0.64GO:0006996organelle organization
0.36GO:0043043peptide biosynthetic process
0.35GO:0044267cellular protein metabolic process
0.35GO:0010467gene expression
0.35GO:0009059macromolecule biosynthetic process
0.82GO:0030742GTP-dependent protein binding
0.74GO:0017137Rab GTPase binding
0.37GO:0003735structural constituent of ribosome
0.87GO:0031084BLOC-2 complex
0.85GO:0031901early endosome membrane
0.75GO:0005765lysosomal membrane
0.70GO:0005783endoplasmic reticulum
0.36GO:0005840ribosome
sp|Q86YW0|PLCZ1_HUMAN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
Search
0.52Phosphoinositide phospholipase C
0.74GO:0007343egg activation
0.72GO:0016042lipid catabolic process
0.65GO:0006816calcium ion transport
0.62GO:0035556intracellular signal transduction
0.53GO:0001525angiogenesis
0.50GO:0042127regulation of cell proliferation
0.40GO:0007340acrosome reaction
0.37GO:0046488phosphatidylinositol metabolic process
0.32GO:0065009regulation of molecular function
0.81GO:0004435phosphatidylinositol phospholipase C activity
0.63GO:0004871signal transducer activity
0.60GO:0005509calcium ion binding
0.32GO:0005085guanyl-nucleotide exchange factor activity
0.59GO:0005829cytosol
0.35GO:0031965nuclear membrane
0.33GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
0.81EC:3.1.4.11 GO:0004435
0.81KEGG:R03435 GO:0004435
sp|Q86YW5|TRML1_HUMAN
Trem-like transcript 1 protein
Search
TREML1
0.97Triggering receptor expressed on myeloid cells like 1
0.38GO:0030168platelet activation
0.38GO:0019722calcium-mediated signaling
0.39GO:0031091platelet alpha granule
0.37GO:0009986cell surface
0.30GO:0044425membrane part
sp|Q86YW7|GPHB5_HUMAN
Glycoprotein hormone beta-5
Search
GPHB5
0.97Glycoprotein hormone beta-5
0.75GO:0010469regulation of receptor activity
0.67GO:0002155regulation of thyroid hormone mediated signaling pathway
0.62GO:0030819positive regulation of cAMP biosynthetic process
0.52GO:0007166cell surface receptor signaling pathway
0.48GO:0009755hormone-mediated signaling pathway
0.47GO:0007267cell-cell signaling
0.46GO:0007186G-protein coupled receptor signaling pathway
0.79GO:0005179hormone activity
0.65GO:0031531thyrotropin-releasing hormone receptor binding
0.54GO:0046982protein heterodimerization activity
0.66GO:0005576extracellular region
0.37GO:0005737cytoplasm
0.30GO:0016020membrane
sp|Q86YW9|MD12L_HUMAN
Mediator of RNA polymerase II transcription subunit 12-like protein
Search
MED12
0.82Mediator of RNA polymerase II transcription subunit 12
0.67GO:0006357regulation of transcription by RNA polymerase II
0.49GO:0006366transcription by RNA polymerase II
0.48GO:0045893positive regulation of transcription, DNA-templated
0.47GO:0090245axis elongation involved in somitogenesis
0.47GO:0048702embryonic neurocranium morphogenesis
0.47GO:1990403embryonic brain development
0.46GO:0036342post-anal tail morphogenesis
0.46GO:0030521androgen receptor signaling pathway
0.46GO:0014003oligodendrocyte development
0.46GO:0014044Schwann cell development
0.79GO:0008013beta-catenin binding
0.74GO:0001104RNA polymerase II transcription cofactor activity
0.53GO:0001190transcriptional activator activity, RNA polymerase II transcription factor binding
0.51GO:0003713transcription coactivator activity
0.47GO:0046966thyroid hormone receptor binding
0.46GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding
0.45GO:0008022protein C-terminus binding
0.43GO:0003682chromatin binding
0.43GO:0019904protein domain specific binding
0.40GO:0004872receptor activity
0.76GO:0016592mediator complex
0.37GO:0000151ubiquitin ligase complex
0.30GO:0016020membrane
sp|Q86YZ3|HORN_HUMAN
Hornerin
Search
HRNR
0.94Hornerin
0.59GO:0061436establishment of skin barrier
0.49GO:0031424keratinization
0.48GO:0043312neutrophil degranulation
0.47GO:0043163cell envelope organization
0.39GO:0002244hematopoietic progenitor cell differentiation
0.36GO:1903506regulation of nucleic acid-templated transcription
0.36GO:2000112regulation of cellular macromolecule biosynthetic process
0.35GO:0010468regulation of gene expression
0.35GO:0071277cellular response to calcium ion
0.68GO:0005509calcium ion binding
0.57GO:0046914transition metal ion binding
0.46GO:0005198structural molecule activity
0.36GO:0003723RNA binding
0.35GO:0003713transcription coactivator activity
0.35GO:0046965retinoid X receptor binding
0.35GO:0042802identical protein binding
0.35GO:0035255ionotropic glutamate receptor binding
0.35GO:0046966thyroid hormone receptor binding
0.35GO:0031489myosin V binding
0.69GO:0001533cornified envelope
0.56GO:0036457keratohyalin granule
0.49GO:0048471perinuclear region of cytoplasm
0.48GO:0035578azurophil granule lumen
0.46GO:0070062extracellular exosome
0.40GO:0005634nucleus
0.39GO:1904724tertiary granule lumen
0.35GO:0044327dendritic spine head
0.35GO:0043204perikaryon
0.34GO:0005844polysome
0.31EC:3.6.1.3 GO:0016887
sp|Q86Z02|HIPK1_HUMAN
Homeodomain-interacting protein kinase 1
Search
HIPK1
0.88Homeodomain-interacting protein kinase 1
0.70GO:0060235lens induction in camera-type eye
0.69GO:0061072iris morphogenesis
0.68GO:0060059embryonic retina morphogenesis in camera-type eye
0.68GO:0072577endothelial cell apoptotic process
0.67GO:0010842retina layer formation
0.67GO:0048596embryonic camera-type eye morphogenesis
0.67GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.65GO:0010803regulation of tumor necrosis factor-mediated signaling pathway
0.64GO:0007224smoothened signaling pathway
0.64GO:0097191extrinsic apoptotic signaling pathway
0.63GO:0004672protein kinase activity
0.54GO:0030554adenyl nucleotide binding
0.53GO:0097367carbohydrate derivative binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.53GO:0008144drug binding
0.46GO:0003677DNA binding
0.46GO:0046790virion binding
0.44GO:0001105RNA polymerase II transcription coactivator activity
0.44GO:0001102RNA polymerase II activating transcription factor binding
0.44GO:0003714transcription corepressor activity
0.65GO:0016605PML body
0.60GO:0016607nuclear speck
0.59GO:0005813centrosome
0.53GO:0005829cytosol
0.42GO:0090575RNA polymerase II transcription factor complex
0.32GO:0005840ribosome
sp|Q86Z14|KLOTB_HUMAN
Beta-klotho
Search
KLB
0.92Beta-klotho
0.68GO:0090080positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
0.60GO:0005975carbohydrate metabolic process
0.57GO:0008284positive regulation of cell proliferation
0.51GO:0008286insulin receptor signaling pathway
0.49GO:0007568aging
0.44GO:1901657glycosyl compound metabolic process
0.43GO:0030501positive regulation of bone mineralization
0.42GO:0055074calcium ion homeostasis
0.41GO:0006112energy reserve metabolic process
0.37GO:0051897positive regulation of protein kinase B signaling
0.66GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds
0.66GO:0017134fibroblast growth factor binding
0.64GO:0005104fibroblast growth factor receptor binding
0.43GO:0004871signal transducer activity
0.38GO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37GO:00163031-phosphatidylinositol-3-kinase activity
0.36GO:0005088Ras guanyl-nucleotide exchange factor activity
0.34GO:0005499vitamin D binding
0.33GO:0005179hormone activity
0.33GO:0032559adenyl ribonucleotide binding
0.47GO:0005615extracellular space
0.45GO:0005887integral component of plasma membrane
0.35GO:0016324apical plasma membrane
0.35GO:1903561extracellular vesicle
0.33GO:0005903brush border
0.32GO:0005622intracellular
0.32GO:0012505endomembrane system
0.66EC:3.2.1 GO:0004553
0.38KEGG:R04545 GO:0046934
sp|Q86Z20|CC125_HUMAN
Coiled-coil domain-containing protein 125
Search
CCDC125
0.97Coiled-coil domain-containing protein 125
0.78GO:2000145regulation of cell motility
0.67GO:0035024negative regulation of Rho protein signal transduction
0.64GO:0090630activation of GTPase activity
0.63GO:0051271negative regulation of cellular component movement
0.63GO:0040013negative regulation of locomotion
0.42GO:0005737cytoplasm
sp|Q86Z23|C1QL4_HUMAN
Complement C1q-like protein 4
Search
C1QL4
0.97Complement component 1, q subcomponent-like 4
0.61GO:0048147negative regulation of fibroblast proliferation
0.60GO:0045599negative regulation of fat cell differentiation
0.59GO:0070373negative regulation of ERK1 and ERK2 cascade
0.51GO:0061743motor learning
0.51GO:0099558maintenance of synapse structure
0.50GO:0016322neuron remodeling
0.48GO:0050807regulation of synapse organization
0.34GO:0007626locomotory behavior
0.34GO:0007017microtubule-based process
0.57GO:0042802identical protein binding
0.44GO:0005102receptor binding
0.65GO:0005581collagen trimer
0.62GO:0005576extracellular region
0.52GO:0044301climbing fiber
0.46GO:0098793presynapse
0.37GO:0005737cytoplasm
0.34GO:0005869dynactin complex
0.30GO:0016020membrane
sp|Q8HWS3|RFX6_HUMAN
DNA-binding protein RFX6
Search
RFX6
0.96Regulatory factor X domain-containing protein 1 (Fragment)
0.80GO:0003311pancreatic D cell differentiation
0.80GO:0090104pancreatic epsilon cell differentiation
0.77GO:0003310pancreatic A cell differentiation
0.75GO:0003309type B pancreatic cell differentiation
0.74GO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.68GO:0042593glucose homeostasis
0.67GO:0006366transcription by RNA polymerase II
0.66GO:0045944positive regulation of transcription by RNA polymerase II
0.47GO:0021914negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
0.46GO:0021516dorsal spinal cord development
0.71GO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.70GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding
0.57GO:0000987proximal promoter sequence-specific DNA binding
0.44GO:0000982transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43GO:0003682chromatin binding
0.63GO:0005730nucleolus
sp|Q8IU54|IFNL1_HUMAN
Interferon lambda-1
Search
0.97Interferon lambda
0.85GO:0007259JAK-STAT cascade
0.79GO:0050778positive regulation of immune response
0.78GO:0051607defense response to virus
0.76GO:0010469regulation of receptor activity
0.57GO:0050863regulation of T cell activation
0.55GO:0045345positive regulation of MHC class I biosynthetic process
0.55GO:0032696negative regulation of interleukin-13 production
0.55GO:0032714negative regulation of interleukin-5 production
0.54GO:0045087innate immune response
0.54GO:0002829negative regulation of type 2 immune response
0.81GO:0005125cytokine activity
0.57GO:0032003interleukin-28 receptor binding
0.56GO:0032002interleukin-28 receptor complex
0.51GO:0005576extracellular region
0.45GO:0005622intracellular
sp|Q8IU57|INLR1_HUMAN
Interferon lambda receptor 1
Search
IFNLR1
0.93Interferon lambda receptor 1
0.76GO:0050691regulation of defense response to virus by host
0.74GO:0002385mucosal immune response
0.65GO:0051607defense response to virus
0.53GO:0019221cytokine-mediated signaling pathway
0.50GO:0034342response to type III interferon
0.41GO:0008285negative regulation of cell proliferation
0.54GO:0004896cytokine receptor activity
0.38GO:0005515protein binding
0.83GO:0032002interleukin-28 receptor complex
sp|Q8IU60|DCP2_HUMAN
m7GpppN-mRNA hydrolase
Search
DCP2
0.91mRNA decapping enzyme
0.59GO:0071044histone mRNA catabolic process
0.59GO:1904872regulation of telomerase RNA localization to Cajal body
0.58GO:0032211negative regulation of telomere maintenance via telomerase
0.52GO:0090503RNA phosphodiester bond hydrolysis, exonucleolytic
0.49GO:0000290deadenylation-dependent decapping of nuclear-transcribed mRNA
0.37GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.36GO:0043928exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.35GO:0043488regulation of mRNA stability
0.71GO:0030145manganese ion binding
0.60GO:0050072m7G(5')pppN diphosphatase activity
0.58GO:0003723RNA binding
0.54GO:00045345'-3' exoribonuclease activity
0.33GO:0005515protein binding
0.56GO:0016442RISC complex
0.56GO:0000932P-body
0.51GO:0030054cell junction
0.48GO:0005654nucleoplasm
0.34GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
0.60EC:3.6.1.30 GO:0050072
sp|Q8IU68|TMC8_HUMAN
Transmembrane channel-like protein 8
Search
TMC8
0.72Transmembrane channel-like protein 8
0.65GO:0032460negative regulation of protein oligomerization
0.64GO:1902041regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.63GO:0055069zinc ion homeostasis
0.62GO:0032091negative regulation of protein binding
0.59GO:0001558regulation of cell growth
0.36GO:0006811ion transport
0.55GO:0005102receptor binding
0.36GO:0030246carbohydrate binding
0.59GO:0031965nuclear membrane
0.54GO:0005794Golgi apparatus
0.54GO:0005783endoplasmic reticulum
0.41GO:0070062extracellular exosome
0.37GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.37GO:0031984organelle subcompartment
0.30GO:0031224intrinsic component of membrane
sp|Q8IU80|TMPS6_HUMAN
Transmembrane protease serine 6
Search
TMPRSS6
0.95Transmembrane protease serine 6
0.60GO:0042730fibrinolysis
0.60GO:0006508proteolysis
0.58GO:0030514negative regulation of BMP signaling pathway
0.54GO:0000122negative regulation of transcription by RNA polymerase II
0.53GO:0006879cellular iron ion homeostasis
0.52GO:0045944positive regulation of transcription by RNA polymerase II
0.38GO:0032501multicellular organismal process
0.37GO:0022617extracellular matrix disassembly
0.36GO:0009653anatomical structure morphogenesis
0.35GO:0007599hemostasis
0.68GO:0004252serine-type endopeptidase activity
0.36GO:0005044scavenger receptor activity
0.35GO:0004222metalloendopeptidase activity
0.35GO:0004896cytokine receptor activity
0.34GO:0005515protein binding
0.34GO:0004792thiosulfate sulfurtransferase activity
0.34GO:0005509calcium ion binding
0.52GO:0005615extracellular space
0.44GO:0005886plasma membrane
0.34GO:0043025neuronal cell body
0.33GO:0031982vesicle
0.33GO:0043230extracellular organelle
0.33GO:0030425dendrite
0.32GO:0005622intracellular
0.32GO:0012505endomembrane system
0.32GO:0045177apical part of cell
0.32GO:0009986cell surface
0.68EC:3.4.21 GO:0004252
0.34KEGG:R01931 GO:0004792
sp|Q8IU81|I2BP1_HUMAN
Interferon regulatory factor 2-binding protein 1
Search
IRF2BP1
0.94Interferon regulatory factor 2 binding protein 1
0.39GO:0000122negative regulation of transcription by RNA polymerase II
0.37GO:0006351transcription, DNA-templated
0.37GO:0006417regulation of translation
0.34GO:0045944positive regulation of transcription by RNA polymerase II
0.53GO:0046872metal ion binding
0.38GO:0003714transcription corepressor activity
0.38GO:0005515protein binding
0.35GO:0016740transferase activity
0.35GO:0003723RNA binding
0.58GO:0005654nucleoplasm
0.35EC:2 GO:0016740
sp|Q8IU85|KCC1D_HUMAN
Calcium/calmodulin-dependent protein kinase type 1D
Search
CAMK1D
0.87Calcium/calmodulin-dependent protein kinase ID
0.81GO:0060267positive regulation of respiratory burst
0.77GO:0090023positive regulation of neutrophil chemotaxis
0.77GO:0032793positive regulation of CREB transcription factor activity
0.77GO:0050766positive regulation of phagocytosis
0.74GO:0050773regulation of dendrite development
0.73GO:0010976positive regulation of neuron projection development
0.69GO:0043065positive regulation of apoptotic process
0.69GO:0043066negative regulation of apoptotic process
0.63GO:0006468protein phosphorylation
0.58GO:0018210peptidyl-threonine modification
0.64GO:0004672protein kinase activity
0.56GO:0005516calmodulin binding
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.56GO:0005634nucleus
0.46GO:0005737cytoplasm
sp|Q8IU89|CERS3_HUMAN
Ceramide synthase 3
Search
CERS3
0.95Ceramide synthase 3
0.66GO:0046513ceramide biosynthetic process
0.59GO:0030216keratinocyte differentiation
0.38GO:1900148negative regulation of Schwann cell migration
0.38GO:1905045negative regulation of Schwann cell proliferation involved in axon regeneration
0.33GO:0006508proteolysis
0.67GO:0050291sphingosine N-acyltransferase activity
0.53GO:0003677DNA binding
0.33GO:0004222metalloendopeptidase activity
0.32GO:0046872metal ion binding
0.59GO:0005634nucleus
0.48GO:0005783endoplasmic reticulum
0.36GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.35GO:0031967organelle envelope
0.35GO:0031090organelle membrane
0.35GO:0031984organelle subcompartment
0.33GO:0005576extracellular region
0.30GO:0016021integral component of membrane
0.67EC:2.3.1.24 GO:0050291
sp|Q8IU99|CAHM1_HUMAN
Calcium homeostasis modulator protein 1
Search
CALHM1
0.97Calcium homeostasis modulator protein 1
0.61GO:0050917sensory perception of umami taste
0.60GO:0050916sensory perception of sweet taste
0.59GO:0098655cation transmembrane transport
0.59GO:0050913sensory perception of bitter taste
0.57GO:0015867ATP transport
0.55GO:0051260protein homooligomerization
0.54GO:0034765regulation of ion transmembrane transport
0.54GO:0006816calcium ion transport
0.46GO:0098660inorganic ion transmembrane transport
0.79GO:0005227calcium activated cation channel activity
0.72GO:0022832voltage-gated channel activity
0.55GO:0005262calcium channel activity
0.52GO:0042802identical protein binding
0.50GO:0005887integral component of plasma membrane
0.36GO:0005789endoplasmic reticulum membrane
sp|Q8IUA0|WFDC8_HUMAN
WAP four-disulfide core domain protein 8
Search
WFDC8
0.97LOW QUALITY PROTEIN: WAP four-disulfide core domain protein 8
0.76GO:0010466negative regulation of peptidase activity
0.76GO:0052548regulation of endopeptidase activity
0.43GO:0007596blood coagulation
0.39GO:0006508proteolysis
0.37GO:0006030chitin metabolic process
0.35GO:1900116extracellular negative regulation of signal transduction
0.34GO:0043392negative regulation of DNA binding
0.34GO:0060021palate development
0.34GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway
0.34GO:0048747muscle fiber development
0.78GO:0004867serine-type endopeptidase inhibitor activity
0.39GO:0008233peptidase activity
0.37GO:0008061chitin binding
0.35GO:0050431transforming growth factor beta binding
0.35GO:0048019receptor antagonist activity
0.33GO:0008191metalloendopeptidase inhibitor activity
0.33GO:0005201extracellular matrix structural constituent
0.33GO:0090729toxin activity
0.31GO:0003676nucleic acid binding
0.63GO:0005576extracellular region
0.30GO:0016020membrane
0.39EC:3.4 GO:0008233
sp|Q8IUA7|ABCA9_HUMAN
ATP-binding cassette sub-family A member 9
Search
0.94ATP-binding cassette sub-family A member 8-B
0.56GO:0006869lipid transport
0.54GO:0055085transmembrane transport
0.34GO:0042908xenobiotic transport
0.33GO:0015893drug transport
0.64GO:0042626ATPase activity, coupled to transmembrane movement of substances
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.34GO:0042910xenobiotic transmembrane transporter activity
0.33GO:0015238drug transmembrane transporter activity
0.47GO:0043231intracellular membrane-bounded organelle
0.44GO:0044446intracellular organelle part
0.44GO:0044444cytoplasmic part
0.43GO:0031974membrane-enclosed lumen
0.42GO:0031090organelle membrane
0.41GO:0031975envelope
0.34GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IUB2|WFDC3_HUMAN
WAP four-disulfide core domain protein 3
Search
WFDC3
0.93WAP four-disulfide core domain protein 3
0.76GO:0010466negative regulation of peptidase activity
0.47GO:0052548regulation of endopeptidase activity
0.36GO:0006508proteolysis
0.35GO:0007620copulation
0.76GO:0030414peptidase inhibitor activity
0.48GO:0061135endopeptidase regulator activity
0.37GO:0008233peptidase activity
0.66GO:0005576extracellular region
0.30GO:0044425membrane part
0.37EC:3.4 GO:0008233
sp|Q8IUB3|WF10B_HUMAN
Protein WFDC10B
Search
WFDC10A
0.97WAP four-disulfide core domain protein 10A
0.76GO:0010466negative regulation of peptidase activity
0.41GO:0052548regulation of endopeptidase activity
0.76GO:0030414peptidase inhibitor activity
0.41GO:0061135endopeptidase regulator activity
0.66GO:0005576extracellular region
sp|Q8IUB5|WFD13_HUMAN
WAP four-disulfide core domain protein 13
Search
sp|Q8IUB9|KR191_HUMAN
Keratin-associated protein 19-1
Search
0.97High tyrosine-glycine keratin-associated protein 19.1
0.62GO:0031424keratinization
0.45GO:0016560protein import into peroxisome matrix, docking
0.41GO:0070830bicellular tight junction assembly
0.39GO:0070673response to interleukin-18
0.38GO:0071356cellular response to tumor necrosis factor
0.36GO:0006413translational initiation
0.35GO:0007010cytoskeleton organization
0.41GO:0005515protein binding
0.38GO:0030246carbohydrate binding
0.38GO:0005198structural molecule activity
0.36GO:0003743translation initiation factor activity
0.35GO:0004386helicase activity
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.67GO:0005882intermediate filament
0.51GO:0005829cytosol
0.43GO:0042579microbody
0.41GO:0016327apicolateral plasma membrane
0.40GO:0016324apical plasma membrane
0.40GO:0030139endocytic vesicle
0.40GO:0005923bicellular tight junction
0.38GO:0016328lateral plasma membrane
0.37GO:0005578proteinaceous extracellular matrix
0.30GO:0016021integral component of membrane
sp|Q8IUC0|KR131_HUMAN
Keratin-associated protein 13-1
Search
0.97Keratin-associated protein 14
0.60GO:0031424keratinization
0.39GO:0005515protein binding
0.75GO:0005882intermediate filament
0.50GO:0005829cytosol
sp|Q8IUC1|KR111_HUMAN
Keratin-associated protein 11-1
Search
KRTAP11-1
0.92High sulfur keratin-associated protein 11.1
0.46GO:0031424keratinization
0.34GO:0009405pathogenesis
0.33GO:0065009regulation of molecular function
0.55GO:0005198structural molecule activity
0.35GO:0019855calcium channel inhibitor activity
0.79GO:0045095keratin filament
0.41GO:0005829cytosol
0.33GO:0005576extracellular region
sp|Q8IUC2|KRA81_HUMAN
Keratin-associated protein 8-1
Search
KRTAP8-1
0.97Keratin associated protein 8
0.79GO:0005882intermediate filament
sp|Q8IUC3|KRA71_HUMAN
Keratin-associated protein 7-1
Search
0.79GO:0005882intermediate filament
sp|Q8IUC4|RHPN2_HUMAN
Rhophilin-2
Search
RHPN2
0.62Rhophilin Rho GTPase binding protein 2
0.59GO:0007165signal transduction
0.41GO:0048471perinuclear region of cytoplasm
0.36GO:0005829cytosol
sp|Q8IUC6|TCAM1_HUMAN
TIR domain-containing adapter molecule 1
Search
TICAM1
0.95TIR domain-containing adapter molecule 1
0.79GO:0045087innate immune response
0.63GO:0035666TRIF-dependent toll-like receptor signaling pathway
0.63GO:0043330response to exogenous dsRNA
0.63GO:0140052cellular response to oxidised low-density lipoprotein particle stimulus
0.62GO:0045359positive regulation of interferon-beta biosynthetic process
0.62GO:0045080positive regulation of chemokine biosynthetic process
0.62GO:0002281macrophage activation involved in immune response
0.61GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.61GO:1900017positive regulation of cytokine production involved in inflammatory response
0.61GO:0032816positive regulation of natural killer cell activation
0.64GO:0004871signal transducer activity
0.58GO:0019901protein kinase binding
0.33GO:0008236serine-type peptidase activity
0.32GO:0004672protein kinase activity
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.66GO:0097342ripoptosome
0.43GO:0005776autophagosome
0.40GO:0031410cytoplasmic vesicle
0.38GO:0098805whole membrane
0.37GO:0098588bounding membrane of organelle
0.37GO:0012505endomembrane system
0.35GO:0044446intracellular organelle part
0.30GO:0044425membrane part
sp|Q8IUC8|GLT13_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 13
Search
GALNT13
0.65Polypeptide N-acetylgalactosaminyltransferase
0.73GO:0006486protein glycosylation
0.58GO:0018210peptidyl-threonine modification
0.56GO:0018209peptidyl-serine modification
0.69GO:0030246carbohydrate binding
0.64GO:0016757transferase activity, transferring glycosyl groups
0.45GO:0030145manganese ion binding
0.45GO:0140096catalytic activity, acting on a protein
0.73GO:0000139Golgi membrane
0.48GO:0048471perinuclear region of cytoplasm
0.36GO:0031985Golgi cisterna
0.34GO:0005576extracellular region
0.33GO:0005789endoplasmic reticulum membrane
0.30GO:0031224intrinsic component of membrane
0.64EC:2.4 GO:0016757
sp|Q8IUD2|RB6I2_HUMAN
ELKS/Rab6-interacting/CAST family member 1
Search
ERC1
0.91Putative rab6 gtpase-interacting protein involved in endosome-to-tgn transport
0.59GO:0007252I-kappaB phosphorylation
0.37GO:0042147retrograde transport, endosome to Golgi
0.35GO:0051092positive regulation of NF-kappaB transcription factor activity
0.35GO:0015031protein transport
0.35GO:0043066negative regulation of apoptotic process
0.34GO:0007275multicellular organism development
0.32GO:0006518peptide metabolic process
0.32GO:0043604amide biosynthetic process
0.32GO:1901566organonitrogen compound biosynthetic process
0.32GO:0010467gene expression
0.55GO:0045296cadherin binding
0.38GO:0030165PDZ domain binding
0.37GO:0017137Rab GTPase binding
0.36GO:0043522leucine zipper domain binding
0.32GO:0003735structural constituent of ribosome
0.83GO:0048786presynaptic active zone
0.60GO:0008385IkappaB kinase complex
0.36GO:0000139Golgi membrane
0.36GO:0042734presynaptic membrane
0.32GO:0005840ribosome
sp|Q8IUD6|RN135_HUMAN
E3 ubiquitin-protein ligase RNF135
Search
RNF135
0.93Ring finger protein 135
0.64GO:0032728positive regulation of interferon-beta production
0.58GO:0016567protein ubiquitination
0.57GO:0080134regulation of response to stress
0.55GO:0050776regulation of immune response
0.43GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process
0.42GO:0045087innate immune response
0.42GO:0023051regulation of signaling
0.42GO:0010646regulation of cell communication
0.42GO:0043066negative regulation of apoptotic process
0.41GO:0048585negative regulation of response to stimulus
0.58GO:0004842ubiquitin-protein transferase activity
0.56GO:0042802identical protein binding
0.55GO:0043021ribonucleoprotein complex binding
0.49GO:0046872metal ion binding
0.46GO:0089720caspase binding
0.44GO:0016874ligase activity
0.44GO:0030674protein binding, bridging
0.43GO:0061659ubiquitin-like protein ligase activity
0.38GO:1902936phosphatidylinositol bisphosphate binding
0.37GO:0005096GTPase activator activity
0.42GO:0005737cytoplasm
0.39GO:0012505endomembrane system
0.38GO:0043231intracellular membrane-bounded organelle
0.36GO:0031968organelle outer membrane
0.36GO:0031301integral component of organelle membrane
0.33GO:0031984organelle subcompartment
0.33GO:0019005SCF ubiquitin ligase complex
0.32GO:0070013intracellular organelle lumen
0.32GO:0005887integral component of plasma membrane
0.44EC:6 GO:0016874
0.58KEGG:R03876 GO:0004842
sp|Q8IUE0|TF2LY_HUMAN
Homeobox protein TGIF2LY
Search
TGIF2LX
0.97Homeobox protein TGIF2LY
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.40GO:0006351transcription, DNA-templated
0.37GO:0007283spermatogenesis
0.36GO:1902680positive regulation of RNA biosynthetic process
0.33GO:0006270DNA replication initiation
0.33GO:0016310phosphorylation
0.32GO:0055114oxidation-reduction process
0.55GO:0003677DNA binding
0.37GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35GO:0005515protein binding
0.34GO:0019205nucleobase-containing compound kinase activity
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0004497monooxygenase activity
0.61GO:0005634nucleus
0.30GO:0016020membrane
sp|Q8IUE1|TF2LX_HUMAN
Homeobox protein TGIF2LX
Search
TGIF2LX
0.94TGFB-induced factor 2-like protein, X-linked
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.41GO:0006351transcription, DNA-templated
0.36GO:0007283spermatogenesis
0.35GO:1902680positive regulation of RNA biosynthetic process
0.33GO:0006270DNA replication initiation
0.33GO:0016310phosphorylation
0.32GO:0055114oxidation-reduction process
0.55GO:0003677DNA binding
0.36GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35GO:0005515protein binding
0.34GO:0019205nucleobase-containing compound kinase activity
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0004497monooxygenase activity
0.61GO:0005634nucleus
0.30GO:0016020membrane
sp|Q8IUE6|H2A2B_HUMAN
Histone H2A type 2-B
Search
sp|Q8IUF1|CBWD2_HUMAN
COBW domain-containing protein 2
Search
0.71Cobalamin synthase W domain-containing protein 3
0.53GO:0032559adenyl ribonucleotide binding
0.52GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0008144drug binding
sp|Q8IUF8|MINA_HUMAN
Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA
Search
RIOX2
0.94Ribosomal oxygenase 2
0.74GO:0000122negative regulation of transcription by RNA polymerase II
0.66GO:0030961peptidyl-arginine hydroxylation
0.64GO:0070544histone H3-K36 demethylation
0.63GO:0034720histone H3-K4 demethylation
0.57GO:0006338chromatin remodeling
0.46GO:0042254ribosome biogenesis
0.42GO:0006351transcription, DNA-templated
0.40GO:0055114oxidation-reduction process
0.39GO:0008283cell proliferation
0.39GO:0042127regulation of cell proliferation
0.82GO:0001191transcriptional repressor activity, RNA polymerase II transcription factor binding
0.72GO:0042802identical protein binding
0.64GO:0032453histone demethylase activity (H3-K4 specific)
0.64GO:0051864histone demethylase activity (H3-K36 specific)
0.40GO:0046872metal ion binding
0.73GO:0005730nucleolus
0.71GO:0005667transcription factor complex
0.68GO:0005829cytosol
0.38GO:0005654nucleoplasm
0.64EC:1.14.11.27 GO:0051864
sp|Q8IUG1|KRA13_HUMAN
Keratin-associated protein 1-3
Search
0.97Keratin intermediate-filament type I protein variant 2
0.40GO:0031424keratinization
0.37GO:0030280structural constituent of epidermis
0.35GO:0042802identical protein binding
0.34GO:0039660structural constituent of virion
0.83GO:0045095keratin filament
0.37GO:0005829cytosol
sp|Q8IUG5|MY18B_HUMAN
Unconventional myosin-XVIIIb
Search
MYO18B
0.80Unconventional myosin-XVIIIb
0.73GO:0007018microtubule-based movement
0.61GO:0048739cardiac muscle fiber development
0.58GO:0001570vasculogenesis
0.55GO:0001701in utero embryonic development
0.38GO:1903028positive regulation of opsonization
0.38GO:0090164asymmetric Golgi ribbon formation
0.37GO:0043030regulation of macrophage activation
0.37GO:0031032actomyosin structure organization
0.37GO:0050714positive regulation of protein secretion
0.37GO:0048194Golgi vesicle budding
0.73GO:0003777microtubule motor activity
0.73GO:0008017microtubule binding
0.73GO:0003779actin binding
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.51GO:0032403protein complex binding
0.37GO:0008094DNA-dependent ATPase activity
0.35GO:0003677DNA binding
0.33GO:0004703G-protein coupled receptor kinase activity
0.76GO:0016459myosin complex
0.58GO:0031941filamentous actin
0.57GO:0030018Z disc
0.37GO:0042641actomyosin
0.36GO:0005802trans-Golgi network
0.36GO:0000139Golgi membrane
0.34GO:0005634nucleus
0.34GO:0005903brush border
0.34GO:0045335phagocytic vesicle
0.33EC:2.7.11.16 GO:0004703
sp|Q8IUH2|CREG2_HUMAN
Protein CREG2
Search
CREG2
0.97Cellular repressor of E1A-stimulated genes 2
0.32GO:2000112regulation of cellular macromolecule biosynthetic process
0.32GO:1903506regulation of nucleic acid-templated transcription
0.32GO:0010468regulation of gene expression
0.56GO:0048037cofactor binding
0.32GO:0016874ligase activity
0.32GO:0003677DNA binding
0.56GO:0005794Golgi apparatus
0.55GO:0005783endoplasmic reticulum
0.37GO:0005576extracellular region
0.30GO:0044425membrane part
0.32EC:6 GO:0016874
sp|Q8IUH3|RBM45_HUMAN
RNA-binding protein 45
Search
RBM45
0.95Developmentally regulated RNA-binding protein 1
0.37GO:0007399nervous system development
0.37GO:0030154cell differentiation
0.59GO:0003723RNA binding
0.34GO:0005515protein binding
0.46GO:0005634nucleus
0.40GO:0005737cytoplasm
sp|Q8IUH4|ZDH13_HUMAN
Palmitoyltransferase ZDHHC13
Search
ZDHHC13
0.58Palmitoyltransferase
0.77GO:1903830magnesium ion transmembrane transport
0.44GO:0042665regulation of ectodermal cell fate specification
0.44GO:0060803BMP signaling pathway involved in mesodermal cell fate specification
0.41GO:0030510regulation of BMP signaling pathway
0.40GO:0018345protein palmitoylation
0.39GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.39GO:0044872lipoprotein localization
0.37GO:0015031protein transport
0.36GO:0007409axonogenesis
0.79GO:0019706protein-cysteine S-palmitoyltransferase activity
0.77GO:0015095magnesium ion transmembrane transporter activity
0.38GO:0042802identical protein binding
0.36GO:0004871signal transducer activity
0.57GO:0030660Golgi-associated vesicle membrane
0.55GO:0000139Golgi membrane
0.52GO:0005783endoplasmic reticulum
0.40GO:0016235aggresome
0.39GO:0030659cytoplasmic vesicle membrane
0.30GO:0016021integral component of membrane
0.79EC:2.3.1.225 GO:0019706
sp|Q8IUH5|ZDH17_HUMAN
Palmitoyltransferase ZDHHC17
Search
ZDHHC17
0.57Palmitoyltransferase
0.76GO:1903830magnesium ion transmembrane transport
0.56GO:0018345protein palmitoylation
0.53GO:0042953lipoprotein transport
0.44GO:0007409axonogenesis
0.38GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35GO:0007165signal transduction
0.78GO:0016409palmitoyltransferase activity
0.77GO:0019707protein-cysteine S-acyltransferase activity
0.76GO:0015095magnesium ion transmembrane transporter activity
0.51GO:0042802identical protein binding
0.35GO:0004871signal transducer activity
0.57GO:0016235aggresome
0.52GO:0030660Golgi-associated vesicle membrane
0.51GO:0000139Golgi membrane
0.39GO:0042734presynaptic membrane
0.37GO:0030659cytoplasmic vesicle membrane
0.37GO:0030054cell junction
0.30GO:0031224intrinsic component of membrane
0.78EC:2.3.1 GO:0016409
sp|Q8IUH8|SPP2C_HUMAN
Signal peptide peptidase-like 2C
Search
SPPL2C
0.83Intramembrane protease 5
0.76GO:0031293membrane protein intracellular domain proteolysis
0.50GO:0006509membrane protein ectodomain proteolysis
0.44GO:0050819negative regulation of coagulation
0.43GO:0050776regulation of immune response
0.34GO:0007166cell surface receptor signaling pathway
0.34GO:0007186G-protein coupled receptor signaling pathway
0.74GO:0042500aspartic endopeptidase activity, intramembrane cleaving
0.52GO:0042803protein homodimerization activity
0.35GO:0004930G-protein coupled receptor activity
0.62GO:0071458integral component of cytoplasmic side of endoplasmic reticulum membrane
0.62GO:0071556integral component of lumenal side of endoplasmic reticulum membrane
0.53GO:0005765lysosomal membrane
0.51GO:0030660Golgi-associated vesicle membrane
0.44GO:0010008endosome membrane
0.43GO:0005813centrosome
0.42GO:0015629actin cytoskeleton
0.41GO:0005654nucleoplasm
0.38GO:0005886plasma membrane
0.35GO:0000139Golgi membrane
0.74EC:3.4.23 GO:0042500
sp|Q8IUI4|S29P2_HUMAN
Putative protein SNX29P2
Search
SNX29
0.74Sorting nexin 29
0.37GO:0007018microtubule-based movement
0.35GO:0048741skeletal muscle fiber development
0.33GO:0042045epithelial fluid transport
0.33GO:0010765positive regulation of sodium ion transport
0.33GO:0038166angiotensin-activated signaling pathway
0.33GO:0031440regulation of mRNA 3'-end processing
0.33GO:0006611protein export from nucleus
0.33GO:0044070regulation of anion transport
0.33GO:0051592response to calcium ion
0.33GO:0097193intrinsic apoptotic signaling pathway
0.76GO:0035091phosphatidylinositol binding
0.37GO:0003777microtubule motor activity
0.35GO:0016887ATPase activity
0.33GO:2001070starch binding
0.33GO:0004013adenosylhomocysteinase activity
0.33GO:0042802identical protein binding
0.32GO:0003676nucleic acid binding
0.32GO:0046872metal ion binding
0.40GO:0070062extracellular exosome
0.38GO:0005871kinesin complex
0.32GO:0005829cytosol
0.32GO:0043231intracellular membrane-bounded organelle
0.30GO:0031224intrinsic component of membrane
0.35EC:3.6.1.3 GO:0016887
sp|Q8IUI8|CRLF3_HUMAN
Cytokine receptor-like factor 3
Search
CRLF3
0.97Cytokine receptor like factor 3
0.85GO:0071158positive regulation of cell cycle arrest
0.84GO:0046427positive regulation of JAK-STAT cascade
0.82GO:0030308negative regulation of cell growth
0.82GO:0000082G1/S transition of mitotic cell cycle
0.74GO:0045944positive regulation of transcription by RNA polymerase II
0.73GO:0042802identical protein binding
0.67GO:0005829cytosol
0.55GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IUK5|PLDX1_HUMAN
Plexin domain-containing protein 1
Search
PLXDC1
0.90Plexin domain-containing protein 1
0.71GO:0001525angiogenesis
0.39GO:0021510spinal cord development
0.35GO:0005515protein binding
0.33GO:0032550purine ribonucleoside binding
0.33GO:0019001guanyl nucleotide binding
0.32GO:0032555purine ribonucleotide binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0043235receptor complex
0.42GO:0005886plasma membrane
0.39GO:0005737cytoplasm
0.38GO:0043025neuronal cell body
0.38GO:0030425dendrite
0.37GO:0005923bicellular tight junction
0.35GO:0005615extracellular space
0.34GO:1903561extracellular vesicle
0.30GO:0044425membrane part
sp|Q8IUK8|CBLN2_HUMAN
Cerebellin-2
Search
CBLN2
0.95Cerebellin 2 precursor
0.81GO:0051965positive regulation of synapse assembly
0.71GO:1900454positive regulation of long term synaptic depression
0.69GO:0090394negative regulation of excitatory postsynaptic potential
0.68GO:0021684cerebellar granular layer formation
0.66GO:0021533cell differentiation in hindbrain
0.65GO:0007157heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.62GO:0021953central nervous system neuron differentiation
0.55GO:0009306protein secretion
0.38GO:0048168regulation of neuronal synaptic plasticity
0.36GO:0007268chemical synaptic transmission
0.58GO:0042803protein homodimerization activity
0.35GO:0003676nucleic acid binding
0.33GO:0046872metal ion binding
0.60GO:0005615extracellular space
0.58GO:0045202synapse
0.42GO:0098590plasma membrane region
0.41GO:0030054cell junction
0.30GO:0016021integral component of membrane
sp|Q8IUL8|CILP2_HUMAN
Cartilage intermediate layer protein 2
Search
CILP
0.95Cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
0.80GO:0043569negative regulation of insulin-like growth factor receptor signaling pathway
0.50GO:0030246carbohydrate binding
0.46GO:0004035alkaline phosphatase activity
0.45GO:0004551nucleotide diphosphatase activity
0.36GO:0030554adenyl nucleotide binding
0.36GO:0097367carbohydrate derivative binding
0.36GO:0008144drug binding
0.36GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0003677DNA binding
0.66GO:0031012extracellular matrix
0.66GO:0005615extracellular space
0.46GO:1903561extracellular vesicle
0.46EC:3.1.3.1 GO:0004035
sp|Q8IUM7|NPAS4_HUMAN
Neuronal PAS domain-containing protein 4
Search
NPAS4
0.95Neuronal PAS domain-containing protein 4
0.74GO:0071386cellular response to corticosterone stimulus
0.74GO:1904862inhibitory synapse assembly
0.72GO:0060080inhibitory postsynaptic potential
0.70GO:0007614short-term memory
0.69GO:0032228regulation of synaptic transmission, GABAergic
0.69GO:0035176social behavior
0.69GO:0007616long-term memory
0.67GO:0007612learning
0.67GO:0048167regulation of synaptic plasticity
0.64GO:0060079excitatory postsynaptic potential
0.68GO:0046983protein dimerization activity
0.66GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
0.39GO:0051287NAD binding
0.37GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.62GO:0098794postsynapse
0.61GO:0005634nucleus
0.60GO:0005667transcription factor complex
0.31GO:0044446intracellular organelle part
0.37EC:1.1.1 GO:0016616
sp|Q8IUN9|CLC10_HUMAN
C-type lectin domain family 10 member A
Search
0.92Macrophage galactose N-acetyl-galactosamine-specific lectin 2
0.45GO:0055088lipid homeostasis
0.45GO:0031668cellular response to extracellular stimulus
0.44GO:0031647regulation of protein stability
0.43GO:0009100glycoprotein metabolic process
0.40GO:0006897endocytosis
0.38GO:0002248connective tissue replacement involved in inflammatory response wound healing
0.38GO:0002223stimulatory C-type lectin receptor signaling pathway
0.37GO:0030282bone mineralization
0.37GO:0002250adaptive immune response
0.36GO:0045087innate immune response
0.69GO:0030246carbohydrate binding
0.47GO:0042803protein homodimerization activity
0.42GO:0004873asialoglycoprotein receptor activity
0.34GO:0046872metal ion binding
0.32GO:0003676nucleic acid binding
0.35GO:0005581collagen trimer
0.34GO:0005886plasma membrane
0.33GO:0005576extracellular region
0.30GO:0016021integral component of membrane
sp|Q8IUQ0|CLVS1_HUMAN
Clavesin-1
Search
CLVS1
0.89Retinaldehyde-binding protein 1-like protein 1
0.84GO:0007040lysosome organization
0.85GO:0080025phosphatidylinositol-3,5-bisphosphate binding
0.80GO:0005802trans-Golgi network
0.80GO:0030136clathrin-coated vesicle
0.76GO:0005768endosome
0.41GO:0044433cytoplasmic vesicle part
0.40GO:0098805whole membrane
0.40GO:0098588bounding membrane of organelle
sp|Q8IUQ4|SIAH1_HUMAN
E3 ubiquitin-protein ligase SIAH1
Search
SIAH1
0.56E3 ubiquitin-protein ligase
0.73GO:0006511ubiquitin-dependent protein catabolic process
0.72GO:0016567protein ubiquitination
0.70GO:0007275multicellular organism development
0.55GO:2001244positive regulation of intrinsic apoptotic signaling pathway
0.41GO:0051402neuron apoptotic process
0.38GO:0010498proteasomal protein catabolic process
0.38GO:0031648protein destabilization
0.37GO:0007283spermatogenesis
0.37GO:0007141male meiosis I
0.36GO:0040014regulation of multicellular organism growth
0.63GO:0008270zinc ion binding
0.54GO:0008022protein C-terminus binding
0.52GO:0016874ligase activity
0.51GO:0061630ubiquitin protein ligase activity
0.49GO:0042802identical protein binding
0.36GO:0097718disordered domain specific binding
0.34GO:0046983protein dimerization activity
0.61GO:0005634nucleus
0.55GO:0030877beta-catenin destruction complex
0.37GO:0005829cytosol
0.37GO:0005769early endosome
0.36GO:0019005SCF ubiquitin ligase complex
0.34GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
0.52EC:6 GO:0016874
sp|Q8IUR0|TPPC5_HUMAN
Trafficking protein particle complex subunit 5
Search
TRAPPC5
0.93Trafficking protein particle complex subunit 5
0.76GO:0048193Golgi vesicle transport
0.35GO:0006901vesicle coating
0.35GO:0006903vesicle targeting
0.34GO:0046907intracellular transport
0.34GO:0065009regulation of molecular function
0.34GO:0006461protein complex assembly
0.33GO:0006979response to oxidative stress
0.33GO:0098869cellular oxidant detoxification
0.32GO:0055114oxidation-reduction process
0.36GO:0017112Rab guanyl-nucleotide exchange factor activity
0.34GO:0005509calcium ion binding
0.33GO:0004602glutathione peroxidase activity
0.82GO:0030008TRAPP complex
0.37GO:0005794Golgi apparatus
0.37GO:0005783endoplasmic reticulum
0.34GO:0098588bounding membrane of organelle
0.34GO:0005829cytosol
0.33GO:0031984organelle subcompartment
0.30GO:0031224intrinsic component of membrane
0.33EC:1.11.1.9 GO:0004602
sp|Q8IUR5|TMTC1_HUMAN
Transmembrane and TPR repeat-containing protein 1
Search
TMTC1
0.92Transmembrane and tetratricopeptide repeat containing 1
0.54GO:0006396RNA processing
0.38GO:0005739mitochondrion
0.30GO:0044425membrane part
sp|Q8IUR6|CRERF_HUMAN
CREB3 regulatory factor
Search
CREBRF
0.94CREB3 regulatory factor
0.62GO:1902213positive regulation of prolactin signaling pathway
0.62GO:1900170negative regulation of glucocorticoid mediated signaling pathway
0.59GO:0042711maternal behavior
0.55GO:2001141regulation of RNA biosynthetic process
0.55GO:2000112regulation of cellular macromolecule biosynthetic process
0.55GO:0010468regulation of gene expression
0.52GO:0006366transcription by RNA polymerase II
0.51GO:0051254positive regulation of RNA metabolic process
0.51GO:0010557positive regulation of macromolecule biosynthetic process
0.51GO:0031328positive regulation of cellular biosynthetic process
0.59GO:0003700DNA binding transcription factor activity
0.53GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding
0.33GO:0005515protein binding
0.53GO:0016604nuclear body
0.33GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q8IUR7|ARMC8_HUMAN
Armadillo repeat-containing protein 8
Search
ARMC8
0.93Armadillo repeat-containing protein 8
0.57GO:0043312neutrophil degranulation
0.45GO:0005515protein binding
0.45GO:0005198structural molecule activity
0.60GO:1904724tertiary granule lumen
0.60GO:0035580specific granule lumen
0.53GO:0005923bicellular tight junction
0.47GO:0005576extracellular region
0.30GO:0031224intrinsic component of membrane
sp|Q8IUS5|EPHX4_HUMAN
Epoxide hydrolase 4
Search
EPHX4
0.97Abhydrolase domain containing 7 (Predicted)
0.43GO:0097176epoxide metabolic process
0.33GO:0006629lipid metabolic process
0.46GO:0016787hydrolase activity
0.34GO:0016746transferase activity, transferring acyl groups
0.36GO:0043231intracellular membrane-bounded organelle
0.34GO:0012505endomembrane system
0.33GO:0031090organelle membrane
0.33GO:0044444cytoplasmic part
0.30GO:0044425membrane part
0.46EC:3 GO:0016787
sp|Q8IUW3|SPA2L_HUMAN
Spermatogenesis-associated protein 2-like protein
Search
SPATA2L
0.97Spermatogeneis-associated protein 2
0.40GO:0006898receptor-mediated endocytosis
0.37GO:0006508proteolysis
0.42GO:0005044scavenger receptor activity
0.39GO:0004252serine-type endopeptidase activity
0.30GO:0031224intrinsic component of membrane
0.39EC:3.4.21 GO:0004252
sp|Q8IUW5|RELL1_HUMAN
RELT-like protein 1
Search
RELL1
0.97Putative tumor necrosis factor receptor superfamily member 19
0.40GO:0010811positive regulation of cell-substrate adhesion
0.32GO:0032259methylation
0.39GO:0005518collagen binding
0.32GO:0008168methyltransferase activity
0.53GO:0015630microtubule cytoskeleton
0.44GO:0005886plasma membrane
0.39GO:0005604basement membrane
0.30GO:0044425membrane part
0.32EC:2.1.1 GO:0008168
sp|Q8IUX1|T126B_HUMAN
Complex I assembly factor TMEM126B, mitochondrial
Search
TMEM126B
0.44Complex I assembly factor TMEM126B, mitochondrial
0.39GO:0032981mitochondrial respiratory chain complex I assembly
0.36GO:0005515protein binding
0.52GO:0005739mitochondrion
0.38GO:0031967organelle envelope
0.38GO:0031090organelle membrane
0.30GO:0044425membrane part
sp|Q8IUX4|ABC3F_HUMAN
DNA dC->dU-editing enzyme APOBEC-3F
Search
0.73Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE transcript variant 1
0.48GO:0010529negative regulation of transposition
0.45GO:0009972cytidine deamination
0.45GO:0080111DNA demethylation
0.43GO:0045071negative regulation of viral genome replication
0.42GO:0045087innate immune response
0.42GO:0051607defense response to virus
0.40GO:0070383DNA cytosine deamination
0.35GO:0016032viral process
0.30GO:0002682regulation of immune system process
0.30GO:0009451RNA modification
0.72GO:0016814hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.63GO:0008270zinc ion binding
0.39GO:0019239deaminase activity
0.35GO:0005515protein binding
0.34GO:0003723RNA binding
0.40GO:0005634nucleus
0.38GO:0000932P-body
0.30GO:0043234protein complex
0.30GO:0044446intracellular organelle part
0.72EC:3.5.4 GO:0016814
sp|Q8IUX7|AEBP1_HUMAN
Adipocyte enhancer-binding protein 1
Search
AEBP1
0.95AE binding protein 1
0.61GO:0006508proteolysis
0.61GO:0000122negative regulation of transcription by RNA polymerase II
0.50GO:0051604protein maturation
0.44GO:0006518peptide metabolic process
0.78GO:0004181metallocarboxypeptidase activity
0.64GO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.63GO:0008270zinc ion binding
0.60GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding
0.60GO:0003714transcription corepressor activity
0.51GO:0004185serine-type carboxypeptidase activity
0.61GO:0005615extracellular space
0.58GO:0031012extracellular matrix
0.35GO:0005856cytoskeleton
0.78EC:3.4.17 GO:0004181
sp|Q8IUX8|EGFL6_HUMAN
Epidermal growth factor-like protein 6
Search
EGFL6
0.97EGF like domain multiple 6
0.79GO:0030198extracellular matrix organization
0.58GO:0010811positive regulation of cell-substrate adhesion
0.43GO:0030903notochord development
0.42GO:0008593regulation of Notch signaling pathway
0.38GO:0007155cell adhesion
0.38GO:0030154cell differentiation
0.37GO:0060347heart trabecula formation
0.37GO:0003171atrioventricular valve development
0.35GO:0010694positive regulation of alkaline phosphatase activity
0.34GO:1903846positive regulation of cellular response to transforming growth factor beta stimulus
0.69GO:0005509calcium ion binding
0.37GO:0005178integrin binding
0.56GO:0005604basement membrane
0.36GO:0005615extracellular space
0.35GO:0034678integrin alpha8-beta1 complex
0.34GO:0030485smooth muscle contractile fiber
0.33GO:0005634nucleus
sp|Q8IUY3|GRAM2_HUMAN
GRAM domain-containing protein 2
Search
GRAMD2A
0.89LOW QUALITY PROTEIN: GRAM domain-containing protein 2
0.35GO:0043547positive regulation of GTPase activity
0.35GO:0007018microtubule-based movement
0.34GO:0035556intracellular signal transduction
0.41GO:0042802identical protein binding
0.35GO:0005096GTPase activator activity
0.35GO:0003777microtubule motor activity
0.35GO:0008017microtubule binding
0.35GO:0003779actin binding
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0046872metal ion binding
0.44GO:0005881cytoplasmic microtubule
0.35GO:0016459myosin complex
0.30GO:0016020membrane
sp|Q8IUZ0|LRC49_HUMAN
Leucine-rich repeat-containing protein 49
Search
LRRC49
0.96Tubulin polyglutamylase complex subunit 4
0.65GO:0018095protein polyglutamylation
0.47GO:0060271cilium assembly
0.45GO:0022008neurogenesis
0.45GO:0007018microtubule-based movement
0.45GO:0003777microtubule motor activity
0.45GO:0008017microtubule binding
0.40GO:0016887ATPase activity
0.39GO:0032559adenyl ribonucleotide binding
0.38GO:0008144drug binding
0.38GO:0035639purine ribonucleoside triphosphate binding
0.69GO:0015630microtubule cytoskeleton
0.68GO:0099513polymeric cytoskeletal fiber
0.54GO:0005829cytosol
0.40GO:0043234protein complex
0.30GO:0031224intrinsic component of membrane
0.40EC:3.6.1.3 GO:0016887
sp|Q8IUZ5|AT2L2_HUMAN
5-phosphohydroxy-L-lysine phospho-lyase
Search
PHYKPL
0.93ethanolamine-phosphate phospho-lyase
0.35GO:0030574collagen catabolic process
0.35GO:0006554lysine catabolic process
0.34GO:0006646phosphatidylethanolamine biosynthetic process
0.69GO:0008483transaminase activity
0.67GO:0030170pyridoxal phosphate binding
0.52GO:0042802identical protein binding
0.48GO:0016829lyase activity
0.45GO:0005739mitochondrion
0.34GO:0070013intracellular organelle lumen
0.33GO:0044446intracellular organelle part
0.30GO:0031224intrinsic component of membrane
0.69EC:2.6.1 GO:0008483
sp|Q8IV01|SYT12_HUMAN
Synaptotagmin-12
Search
SYT12
0.95Synaptotagmin XII
0.84GO:0060291long-term synaptic potentiation
0.84GO:0046928regulation of neurotransmitter secretion
0.52GO:0048791calcium ion-regulated exocytosis of neurotransmitter
0.51GO:0017158regulation of calcium ion-dependent exocytosis
0.50GO:0006906vesicle fusion
0.44GO:0048792spontaneous exocytosis of neurotransmitter
0.33GO:0006659phosphatidylserine biosynthetic process
0.32GO:2000112regulation of cellular macromolecule biosynthetic process
0.32GO:1903506regulation of nucleic acid-templated transcription
0.32GO:0010468regulation of gene expression
0.53GO:0005544calcium-dependent phospholipid binding
0.50GO:0019905syntaxin binding
0.49GO:0030276clathrin binding
0.45GO:0005509calcium ion binding
0.32GO:0043565sequence-specific DNA binding
0.49GO:0098793presynapse
0.40GO:0005886plasma membrane
0.40GO:0099501exocytic vesicle membrane
0.38GO:0030054cell junction
0.32GO:0005634nucleus
0.30GO:0016021integral component of membrane
sp|Q8IV03|LUR1L_HUMAN
Leucine rich adaptor protein 1-like
Search
LURAP1L
0.93Leucine rich adaptor protein 1 like
0.84GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.31GO:0016310phosphorylation
0.31GO:0016301kinase activity
sp|Q8IV04|TB10C_HUMAN
Carabin
Search
TBC1D10C
0.92Carabin
0.84GO:0051534negative regulation of NFAT protein import into nucleus
0.80GO:0050869negative regulation of B cell activation
0.78GO:0070373negative regulation of ERK1 and ERK2 cascade
0.77GO:0042147retrograde transport, endosome to Golgi
0.65GO:0031338regulation of vesicle fusion
0.65GO:0090630activation of GTPase activity
0.54GO:0006886intracellular protein transport
0.47GO:0097202activation of cysteine-type endopeptidase activity
0.45GO:1902017regulation of cilium assembly
0.41GO:0043312neutrophil degranulation
0.62GO:0017137Rab GTPase binding
0.59GO:0005096GTPase activator activity
0.46GO:0030165PDZ domain binding
0.45GO:0045296cadherin binding
0.40GO:0047730carnosine synthase activity
0.36GO:0005085guanyl-nucleotide exchange factor activity
0.35GO:0016887ATPase activity
0.34GO:0032559adenyl ribonucleotide binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.83GO:0031527filopodium membrane
0.66GO:0005829cytosol
0.54GO:0012505endomembrane system
0.39GO:0031982vesicle
0.38GO:0098805whole membrane
0.37GO:0098588bounding membrane of organelle
0.37GO:0005902microvillus
0.36GO:0043230extracellular organelle
0.35GO:0005615extracellular space
0.35GO:0044446intracellular organelle part
0.40EC:6.3.2.11 GO:0047730
sp|Q8IV08|PLD3_HUMAN
Phospholipase D3
Search
PLD3
0.92Phospholipase D family member 3
0.41GO:0016042lipid catabolic process
0.32GO:0006468protein phosphorylation
0.45GO:0004630phospholipase D activity
0.45GO:0070290N-acylphosphatidylethanolamine-specific phospholipase D activity
0.34GO:0005515protein binding
0.33GO:0005509calcium ion binding
0.32GO:0004672protein kinase activity
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.41GO:0005789endoplasmic reticulum membrane
0.37GO:0070062extracellular exosome
0.30GO:0031224intrinsic component of membrane
0.45EC:3.1.4.4 GO:0004630
sp|Q8IV13|CCNJL_HUMAN
Cyclin-J-like protein
Search
CCNJL
0.87Cyclin J like
0.33GO:0006909phagocytosis
0.33GO:0001812positive regulation of type I hypersensitivity
0.33GO:0001805positive regulation of type III hypersensitivity
0.33GO:0032765positive regulation of mast cell cytokine production
0.33GO:0033026negative regulation of mast cell apoptotic process
0.33GO:0002894positive regulation of type II hypersensitivity
0.33GO:0001796regulation of type IIa hypersensitivity
0.33GO:0002554serotonin secretion by platelet
0.33GO:0050878regulation of body fluid levels
0.33GO:0007229integrin-mediated signaling pathway
0.35GO:0005515protein binding
0.33GO:0019767IgE receptor activity
0.33GO:0044877macromolecular complex binding
0.33GO:0005509calcium ion binding
0.32GO:0005198structural molecule activity
0.32GO:0004890GABA-A receptor activity
0.32GO:0001681sialate O-acetylesterase activity
0.32GO:0005230extracellular ligand-gated ion channel activity
0.32GO:0044212transcription regulatory region DNA binding
0.32GO:0003755peptidyl-prolyl cis-trans isomerase activity
0.60GO:0005634nucleus
0.33GO:0009897external side of plasma membrane
0.33GO:0032997Fc receptor complex
0.33GO:0030130clathrin coat of trans-Golgi network vesicle
0.33GO:0030132clathrin coat of coated pit
0.33GO:0070013intracellular organelle lumen
0.33GO:0035866alphav-beta3 integrin-PKCalpha complex
0.33GO:0071133alpha9-beta1 integrin-ADAM8 complex
0.32GO:0005887integral component of plasma membrane
0.32GO:0008275gamma-tubulin small complex
0.32EC:3.1.1.53 GO:0001681
sp|Q8IV16|HDBP1_HUMAN
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
Search
GPIHBP1
0.97Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
0.87GO:0071503response to heparin
0.87GO:0051006positive regulation of lipoprotein lipase activity
0.85GO:0070328triglyceride homeostasis
0.57GO:0090321positive regulation of chylomicron remnant clearance
0.56GO:0034371chylomicron remodeling
0.53GO:0045056transcytosis
0.52GO:0006501C-terminal protein lipidation
0.52GO:0034394protein localization to cell surface
0.51GO:0001523retinoid metabolic process
0.51GO:0042632cholesterol homeostasis
0.89GO:0035478chylomicron binding
0.87GO:0035473lipase binding
0.47GO:0008320protein transmembrane transporter activity
0.46GO:0008289lipid binding
0.86GO:0031362anchored component of external side of plasma membrane
0.52GO:0034364high-density lipoprotein particle
0.50GO:0016323basolateral plasma membrane
0.50GO:0016324apical plasma membrane
0.36GO:0005622intracellular
sp|Q8IV20|LACC1_HUMAN
Laccase domain-containing protein 1
Search
LACC1
0.97Laccase domain-containing protein 1
0.72GO:0005507copper ion binding
0.40GO:0005515protein binding
0.55GO:0042579microbody
sp|Q8IV31|TM139_HUMAN
Transmembrane protein 139
Search
TMEM139
0.47Transmembrane domain-containing protein (Fragment)
0.35GO:0055114oxidation-reduction process
0.38GO:0015035protein disulfide oxidoreductase activity
0.36GO:0005515protein binding
0.33GO:0016740transferase activity
0.30GO:0044425membrane part
0.33EC:2 GO:0016740
sp|Q8IV32|CCD71_HUMAN
Coiled-coil domain-containing protein 71
Search
CCDC71
0.94Coiled-coil domain-containing protein 71
0.53GO:0045600positive regulation of fat cell differentiation
0.44GO:0044255cellular lipid metabolic process
0.43GO:0009405pathogenesis
0.39GO:0003723RNA binding
0.30GO:0031224intrinsic component of membrane
sp|Q8IV33|K0825_HUMAN
Uncharacterized protein KIAA0825
Search
sp|Q8IV35|WDR49_HUMAN
WD repeat-containing protein 49
Search
WDR49
0.95LOW QUALITY PROTEIN: WD repeat-containing protein 49
0.68GO:0005509calcium ion binding
sp|Q8IV36|HID1_HUMAN
Protein HID1
Search
HID1
0.97HID1 domain containing b
0.85GO:0031001response to brefeldin A
0.66GO:0006886intracellular protein transport
0.36GO:0005515protein binding
0.83GO:0000138Golgi trans cisterna
0.82GO:0005797Golgi medial cisterna
0.80GO:0090498extrinsic component of Golgi membrane
0.75GO:0005881cytoplasmic microtubule
0.62GO:0005829cytosol
0.41GO:0070062extracellular exosome
0.30GO:0016021integral component of membrane
sp|Q8IV38|ANKY2_HUMAN
Ankyrin repeat and MYND domain-containing protein 2
Search
ANKMY2
0.96Ankyrin repeat and MYND domain-containing protein 2
0.70GO:0008589regulation of smoothened signaling pathway
0.35GO:0008299isoprenoid biosynthetic process
0.65GO:0019899enzyme binding
0.37GO:0046872metal ion binding
0.36GO:0070567cytidylyltransferase activity
0.44GO:0005929cilium
0.30GO:0031224intrinsic component of membrane
sp|Q8IV42|PSTK_HUMAN
L-seryl-tRNA(Sec) kinase
Search
PSTK
0.96Phosphoseryl-tRNA kinase
0.61GO:0001514selenocysteine incorporation
0.57GO:0016310phosphorylation
0.40GO:0097056selenocysteinyl-tRNA(Sec) biosynthetic process
0.60GO:0016301kinase activity
0.54GO:0000049tRNA binding
0.39GO:0098620seryl-selenocysteinyl-tRNA kinase activity
0.35GO:0032559adenyl ribonucleotide binding
0.35GO:0008144drug binding
0.35GO:0035639purine ribonucleoside triphosphate binding
0.49GO:0005739mitochondrion
0.35GO:0005829cytosol
0.30GO:0016020membrane
sp|Q8IV45|UN5CL_HUMAN
UNC5C-like protein
Search
sp|Q8IV48|ERI1_HUMAN
3'-5' exoribonuclease 1
Search
ERI1
0.97Exoribonuclease 1
0.45GO:0090305nucleic acid phosphodiester bond hydrolysis
0.39GO:0071044histone mRNA catabolic process
0.39GO:0006259DNA metabolic process
0.39GO:0031125rRNA 3'-end processing
0.38GO:0031047gene silencing by RNA
0.50GO:0003676nucleic acid binding
0.49GO:00084083'-5' exonuclease activity
0.37GO:0043022ribosome binding
0.35GO:0016896exoribonuclease activity, producing 5'-phosphomonoesters
0.35GO:0005515protein binding
0.34GO:0046872metal ion binding
0.50GO:0005730nucleolus
0.40GO:0071204histone pre-mRNA 3'end processing complex
0.39GO:0005737cytoplasm
0.34GO:0005654nucleoplasm
0.35EC:3.1.13 GO:0016896
sp|Q8IV50|LYSM2_HUMAN
LysM and putative peptidoglycan-binding domain-containing protein 2
Search
LYSMD2
0.94LysM and peptidoglycan-binding domain-containing protein 2
0.43GO:0006368transcription elongation from RNA polymerase II promoter
0.41GO:0016570histone modification
0.36GO:0005515protein binding
0.67GO:0005654nucleoplasm
0.42GO:0055029nuclear DNA-directed RNA polymerase complex
0.38GO:0043234protein complex
sp|Q8IV53|DEN1C_HUMAN
DENN domain-containing protein 1C
Search
DENND1C
0.95LOW QUALITY PROTEIN: DENN domain-containing protein 1C
0.66GO:0065009regulation of molecular function
0.56GO:0032456endocytic recycling
0.55GO:0032483regulation of Rab protein signal transduction
0.54GO:0048488synaptic vesicle endocytosis
0.45GO:0035745T-helper 2 cell cytokine production
0.44GO:0050852T cell receptor signaling pathway
0.35GO:0015031protein transport
0.33GO:0055085transmembrane transport
0.84GO:0017112Rab guanyl-nucleotide exchange factor activity
0.53GO:0032266phosphatidylinositol-3-phosphate binding
0.51GO:0017124SH3 domain binding
0.35GO:0005509calcium ion binding
0.55GO:0030136clathrin-coated vesicle
0.51GO:0043025neuronal cell body
0.51GO:0030425dendrite
0.51GO:0005829cytosol
0.50GO:0030662coated vesicle membrane
0.49GO:0045202synapse
0.49GO:0005654nucleoplasm
0.37GO:0098590plasma membrane region
0.37GO:0030054cell junction
0.30GO:0016021integral component of membrane
sp|Q8IV56|PRR15_HUMAN
Proline-rich protein 15
Search
PRR15
0.97Proline-rich protein 15
0.70GO:0007275multicellular organism development
sp|Q8IV61|GRP3_HUMAN
Ras guanyl-releasing protein 3
Search
RASGRP3
0.94Ras guanyl-releasing protein 3
0.81GO:0007265Ras protein signal transduction
0.75GO:0043547positive regulation of GTPase activity
0.35GO:0071277cellular response to calcium ion
0.35GO:0007268chemical synaptic transmission
0.35GO:0000165MAPK cascade
0.32GO:0005975carbohydrate metabolic process
0.75GO:0005085guanyl-nucleotide exchange factor activity
0.75GO:0005096GTPase activator activity
0.69GO:0005509calcium ion binding
0.51GO:0019900kinase binding
0.50GO:0017016Ras GTPase binding
0.37GO:0019992diacylglycerol binding
0.33GO:0004871signal transducer activity
0.33GO:0102250linear malto-oligosaccharide phosphorylase activity
0.33GO:0102499SHG alpha-glucan phosphorylase activity
0.33GO:0008184glycogen phosphorylase activity
0.55GO:0032045guanyl-nucleotide exchange factor complex
0.52GO:0048471perinuclear region of cytoplasm
0.35GO:0005829cytosol
0.34GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IV63|VRK3_HUMAN
Inactive serine/threonine-protein kinase VRK3
Search
VRK3
0.97Inactive serine-threonine-protein kinase VRK3
0.63GO:0006468protein phosphorylation
0.55GO:0032516positive regulation of phosphoprotein phosphatase activity
0.54GO:0070373negative regulation of ERK1 and ERK2 cascade
0.47GO:0018209peptidyl-serine modification
0.43GO:0008360regulation of cell shape
0.34GO:2000659regulation of interleukin-1-mediated signaling pathway
0.33GO:0043043peptide biosynthetic process
0.33GO:0034599cellular response to oxidative stress
0.33GO:0006355regulation of transcription, DNA-templated
0.33GO:0010467gene expression
0.63GO:0004672protein kinase activity
0.55GO:0019903protein phosphatase binding
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0003735structural constituent of ribosome
0.33GO:0019901protein kinase binding
0.33GO:0019904protein domain specific binding
0.33GO:0003676nucleic acid binding
0.52GO:0005730nucleolus
0.37GO:0005737cytoplasm
0.33GO:0030529intracellular ribonucleoprotein complex
0.33GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.33GO:0031984organelle subcompartment
0.32GO:0031967organelle envelope
0.32GO:0031090organelle membrane
0.32GO:0043234protein complex
0.30GO:0044425membrane part
sp|Q8IV76|PASD1_HUMAN
Circadian clock protein PASD1
Search
PASD1
0.96PAS domain containing repressor 1
0.67GO:0042754negative regulation of circadian rhythm
0.57GO:2001141regulation of RNA biosynthetic process
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.55GO:0051253negative regulation of RNA metabolic process
0.55GO:0010558negative regulation of macromolecule biosynthetic process
0.55GO:0031327negative regulation of cellular biosynthetic process
0.39GO:0006351transcription, DNA-templated
0.67GO:0001223transcription coactivator binding
0.43GO:0046983protein dimerization activity
0.40GO:0003700DNA binding transcription factor activity
0.37GO:0003677DNA binding
0.72GO:1990512Cry-Per complex
0.61GO:0016607nuclear speck
0.45GO:0005667transcription factor complex
0.36GO:0005737cytoplasm
0.30GO:0016020membrane
sp|Q8IV77|CNGA4_HUMAN
Cyclic nucleotide-gated cation channel alpha-4
Search
CNGA4
0.89Cyclic nucleotide-gated channel cone photoreceptor subunit alpha
0.60GO:0007600sensory perception
0.60GO:0034220ion transmembrane transport
0.59GO:0071804cellular potassium ion transport
0.46GO:0042391regulation of membrane potential
0.35GO:0050896response to stimulus
0.35GO:0051290protein heterotetramerization
0.35GO:0051480regulation of cytosolic calcium ion concentration
0.34GO:0051283negative regulation of sequestering of calcium ion
0.33GO:0060401cytosolic calcium ion transport
0.33GO:0007283spermatogenesis
0.70GO:0005216ion channel activity
0.66GO:0022836gated channel activity
0.59GO:0015079potassium ion transmembrane transporter activity
0.42GO:0030553cGMP binding
0.38GO:0030552cAMP binding
0.34GO:0015054gastrin receptor activity
0.33GO:0015085calcium ion transmembrane transporter activity
0.32GO:0019904protein domain specific binding
0.42GO:0060170ciliary membrane
0.42GO:0005887integral component of plasma membrane
0.41GO:0001750photoreceptor outer segment
0.37GO:0017071intracellular cyclic nucleotide activated cation channel complex
0.35GO:0043204perikaryon
0.34GO:0030660Golgi-associated vesicle membrane
0.34GO:0000139Golgi membrane
0.34GO:0043195terminal bouton
sp|Q8IVA1|PCP2_HUMAN
Purkinje cell protein 2 homolog
Search
PCP2
0.97Purkinje cell-specific protein 2
0.69GO:0050790regulation of catalytic activity
0.42GO:0016056rhodopsin mediated signaling pathway
0.34GO:0060259regulation of feeding behavior
0.33GO:0044093positive regulation of molecular function
0.76GO:0030695GTPase regulator activity
0.39GO:0005085guanyl-nucleotide exchange factor activity
0.34GO:0001965G-protein alpha-subunit binding
0.33GO:0008047enzyme activator activity
0.40GO:0043025neuronal cell body
0.30GO:0016020membrane
sp|Q8IVB4|SL9A9_HUMAN
Sodium/hydrogen exchanger 9
Search
SLC9A9
0.60Sodium/hydrogen exchanger
0.78GO:0006885regulation of pH
0.76GO:0035725sodium ion transmembrane transport
0.62GO:1902600hydrogen ion transmembrane transport
0.52GO:0099587inorganic ion import across plasma membrane
0.50GO:0030004cellular monovalent inorganic cation homeostasis
0.47GO:0071805potassium ion transmembrane transport
0.43GO:0031547brain-derived neurotrophic factor receptor signaling pathway
0.43GO:0097484dendrite extension
0.43GO:0051386regulation of neurotrophin TRK receptor signaling pathway
0.42GO:0060996dendritic spine development
0.81GO:0015385sodium:proton antiporter activity
0.52GO:0015386potassium:proton antiporter activity
0.33GO:0005515protein binding
0.60GO:0055037recycling endosome
0.43GO:0044308axonal spine
0.42GO:0005770late endosome
0.42GO:0010008endosome membrane
0.41GO:0043679axon terminus
0.41GO:0005886plasma membrane
0.41GO:0030425dendrite
0.41GO:0005769early endosome
0.39GO:0005789endoplasmic reticulum membrane
0.37GO:0005739mitochondrion
sp|Q8IVB5|LIX1L_HUMAN
LIX1-like protein
Search
LIX1L
0.97Limb and CNS expressed 1 like
0.85GO:0097352autophagosome maturation
0.48GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q8IVC4|ZN584_HUMAN
Zinc finger protein 584
Search
0.71Zinc finger protein 584
0.54GO:1903506regulation of nucleic acid-templated transcription
0.54GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.36GO:0010467gene expression
0.36GO:0009059macromolecule biosynthetic process
0.35GO:0043043peptide biosynthetic process
0.35GO:1902466positive regulation of histone H3-K27 trimethylation
0.35GO:0044267cellular protein metabolic process
0.35GO:1900114positive regulation of histone H3-K9 trimethylation
0.35GO:0035562negative regulation of chromatin binding
0.51GO:0003676nucleic acid binding
0.51GO:0046872metal ion binding
0.36GO:0003735structural constituent of ribosome
0.34GO:1990841promoter-specific chromatin binding
0.33GO:0005515protein binding
0.43GO:0005622intracellular
0.36GO:1990904ribonucleoprotein complex
0.36GO:0043226organelle
0.30GO:0031224intrinsic component of membrane
sp|Q8IVD9|NUDC3_HUMAN
NudC domain-containing protein 3
Search
NUDCD3
0.97NudC domain-containing protein 3
0.86GO:1905793protein localization to pericentriolar material
0.77GO:0060271cilium assembly
0.54GO:0006457protein folding
0.53GO:0032502developmental process
0.55GO:0051082unfolded protein binding
0.80GO:0005868cytoplasmic dynein complex
0.42GO:0005737cytoplasm
sp|Q8IVE0|CROL2_HUMAN
Putative ciliary rootlet coiled-coil protein-like 2 protein
Search
0.11Putative ciliary rootlet coiled-coil protein-like 2 protein
0.82GO:0007098centrosome cycle
0.69GO:1903566positive regulation of protein localization to cilium
0.66GO:0032053ciliary basal body organization
0.65GO:0045724positive regulation of cilium assembly
0.64GO:0010669epithelial structure maintenance
0.63GO:0045494photoreceptor cell maintenance
0.58GO:0051656establishment of organelle localization
0.56GO:0033365protein localization to organelle
0.33GO:0007062sister chromatid cohesion
0.33GO:0030261chromosome condensation
0.62GO:0019894kinesin binding
0.56GO:0003779actin binding
0.49GO:0005198structural molecule activity
0.33GO:0003774motor activity
0.33GO:0030276clathrin binding
0.33GO:0005543phospholipid binding
0.33GO:0005509calcium ion binding
0.32GO:0046914transition metal ion binding
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0003677DNA binding
0.86GO:0035253ciliary rootlet
0.63GO:0001917photoreceptor inner segment
0.62GO:0005814centriole
0.60GO:0005813centrosome
0.57GO:0015629actin cytoskeleton
0.54GO:0005829cytosol
0.46GO:0005886plasma membrane
0.42GO:0070062extracellular exosome
0.34GO:0005882intermediate filament
0.32GO:0005694chromosome
sp|Q8IVE3|PKHH2_HUMAN
Pleckstrin homology domain-containing family H member 2
Search
PLEKHH2
0.96Pleckstrin like proteiny domain-containing family H member 2
0.57GO:0030835negative regulation of actin filament depolymerization
0.34GO:0001569branching involved in blood vessel morphogenesis
0.34GO:0007411axon guidance
0.33GO:0006351transcription, DNA-templated
0.33GO:1903506regulation of nucleic acid-templated transcription
0.33GO:2000112regulation of cellular macromolecule biosynthetic process
0.33GO:0010468regulation of gene expression
0.53GO:0042802identical protein binding
0.53GO:0003779actin binding
0.34GO:0046983protein dimerization activity
0.33GO:0003677DNA binding
0.32GO:0046872metal ion binding
0.69GO:0005856cytoskeleton
0.57GO:0030027lamellipodium
0.54GO:0016604nuclear body
0.54GO:0044448cell cortex part
0.50GO:0005829cytosol
0.43GO:0005886plasma membrane
sp|Q8IVF1|NTM2A_HUMAN
NUT family member 2A
Search
0.68NUT midline carcinoma family member 1
0.43GO:0005634nucleus
0.38GO:0005737cytoplasm
sp|Q8IVF2|AHNK2_HUMAN
Protein AHNAK2
Search
0.11AHNAK nucleoprotein 2
0.72GO:1901385regulation of voltage-gated calcium channel activity
0.61GO:0043484regulation of RNA splicing
0.55GO:0051259protein oligomerization
0.52GO:0001778plasma membrane repair
0.72GO:0044548S100 protein binding
0.68GO:0045296cadherin binding
0.66GO:0097493structural molecule activity conferring elasticity
0.74GO:0042383sarcolemma
0.71GO:0043034costamere
0.71GO:0044291cell-cell contact zone
0.67GO:0070062extracellular exosome
0.67GO:0045121membrane raft
0.66GO:0005829cytosol
0.62GO:0015629actin cytoskeleton
0.49GO:0030018Z disc
0.49GO:0005634nucleus
0.47GO:0030659cytoplasmic vesicle membrane
sp|Q8IVF4|DYH10_HUMAN
Dynein heavy chain 10, axonemal
Search
DNAH10
0.85Dynein axonemal heavy chain 10
0.74GO:0007018microtubule-based movement
0.33GO:0060271cilium assembly
0.33GO:0015991ATP hydrolysis coupled proton transport
0.33GO:0006289nucleotide-excision repair
0.32GO:2000112regulation of cellular macromolecule biosynthetic process
0.32GO:1903506regulation of nucleic acid-templated transcription
0.32GO:0010468regulation of gene expression
0.31GO:0006508proteolysis
0.75GO:0003777microtubule motor activity
0.57GO:0016887ATPase activity
0.56GO:0045503dynein light chain binding
0.56GO:0051959dynein light intermediate chain binding
0.56GO:0045505dynein intermediate chain binding
0.53GO:0032559adenyl ribonucleotide binding
0.52GO:0008144drug binding
0.52GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0015078hydrogen ion transmembrane transporter activity
0.31GO:0070001aspartic-type peptidase activity
0.77GO:0030286dynein complex
0.40GO:0005929cilium
0.37GO:0032838plasma membrane bounded cell projection cytoplasm
0.36GO:0005874microtubule
0.33GO:0000439core TFIIH complex
0.33GO:0033179proton-transporting V-type ATPase, V0 domain
0.30GO:0031224intrinsic component of membrane
0.57EC:3.6.1.3 GO:0016887
sp|Q8IVF5|TIAM2_HUMAN
T-lymphoma invasion and metastasis-inducing protein 2
Search
TIAM2
0.89T-lymphoma invasion and metastasis-inducing protein 2
0.76GO:0035023regulation of Rho protein signal transduction
0.65GO:0065009regulation of molecular function
0.61GO:0035556intracellular signal transduction
0.37GO:0019216regulation of lipid metabolic process
0.37GO:0043065positive regulation of apoptotic process
0.36GO:0007186G-protein coupled receptor signaling pathway
0.77GO:0005089Rho guanyl-nucleotide exchange factor activity
0.71GO:0005057signal transducer activity, downstream of receptor
0.50GO:0005096GTPase activator activity
0.44GO:0005622intracellular
0.39GO:0070062extracellular exosome
0.39GO:0030175filopodium
0.39GO:0030426growth cone
0.39GO:0030027lamellipodium
0.30GO:0016020membrane
sp|Q8IVF6|AN18A_HUMAN
Ankyrin repeat domain-containing protein 18A
Search
ANKRD18A
0.97Ankyrin repeat domain-containing protein 18A
0.42GO:0031648protein destabilization
0.41GO:0031122cytoplasmic microtubule organization
0.41GO:0065009regulation of molecular function
0.41GO:0031098stress-activated protein kinase signaling cascade
0.41GO:0030705cytoskeleton-dependent intracellular transport
0.40GO:0051260protein homooligomerization
0.40GO:0016055Wnt signaling pathway
0.39GO:0060255regulation of macromolecule metabolic process
0.39GO:0031323regulation of cellular metabolic process
0.39GO:0051171regulation of nitrogen compound metabolic process
0.46GO:0008200ion channel inhibitor activity
0.42GO:0005515protein binding
0.39GO:0003700DNA binding transcription factor activity
0.37GO:0003677DNA binding
0.51GO:0070062extracellular exosome
0.43GO:0005634nucleus
0.42GO:0005813centrosome
0.39GO:0005886plasma membrane
0.34GO:0005737cytoplasm
0.30GO:0016021integral component of membrane
sp|Q8IVF7|FMNL3_HUMAN
Formin-like protein 3
Search
FMNL3
0.88Formin like 3
0.73GO:0030036actin cytoskeleton organization
0.73GO:0016477cell migration
0.69GO:0022604regulation of cell morphogenesis
0.60GO:0065008regulation of biological quality
0.46GO:0030865cortical cytoskeleton organization
0.77GO:0017048Rho GTPase binding
0.74GO:0003779actin binding
0.66GO:0032794GTPase activating protein binding
0.45GO:0045296cadherin binding
0.55GO:0005794Golgi apparatus
0.53GO:0005829cytosol
0.46GO:0005886plasma membrane
sp|Q8IVG5|SAM9L_HUMAN
Sterile alpha motif domain-containing protein 9-like
Search
SAMD9L
0.94LOW QUALITY PROTEIN: sterile alpha motif domain-containing protein 9
0.80GO:0034058endosomal vesicle fusion
0.45GO:0035726common myeloid progenitor cell proliferation
0.44GO:0048536spleen development
0.44GO:0017145stem cell division
0.43GO:0002244hematopoietic progenitor cell differentiation
0.42GO:0042176regulation of protein catabolic process
0.35GO:0006397mRNA processing
0.35GO:0090501RNA phosphodiester bond hydrolysis
0.34GO:0006468protein phosphorylation
0.43GO:0032559adenyl ribonucleotide binding
0.43GO:0008144drug binding
0.43GO:0035639purine ribonucleoside triphosphate binding
0.41GO:0005515protein binding
0.35GO:0004540ribonuclease activity
0.35GO:0003677DNA binding
0.34GO:0004672protein kinase activity
0.65GO:0005769early endosome
0.56GO:0005829cytosol
0.47GO:0043231intracellular membrane-bounded organelle
0.30GO:0016020membrane
sp|Q8IVG9|HUNIN_HUMAN
Humanin
Search
0.56Humanin
0.86GO:1900116extracellular negative regulation of signal transduction
0.84GO:0030595leukocyte chemotaxis
0.78GO:0043066negative regulation of apoptotic process
0.77GO:0006915apoptotic process
0.76GO:0006879cellular iron ion homeostasis
0.70GO:0007186G-protein coupled receptor signaling pathway
0.86GO:0048019receptor antagonist activity
0.79GO:0048471perinuclear region of cytoplasm
0.66GO:0005576extracellular region
0.60GO:0005739mitochondrion
sp|Q8IVH2|FOXP4_HUMAN
Forkhead box protein P4
Search
FOXP4
0.97Forkhead box protein P4
0.56GO:0006355regulation of transcription, DNA-templated
0.56GO:0006351transcription, DNA-templated
0.44GO:0030154cell differentiation
0.44GO:0009653anatomical structure morphogenesis
0.42GO:1901250negative regulation of lung goblet cell differentiation
0.41GO:0060428lung epithelium development
0.39GO:0007507heart development
0.39GO:0009790embryo development
0.39GO:1903507negative regulation of nucleic acid-templated transcription
0.38GO:2000113negative regulation of cellular macromolecule biosynthetic process
0.64GO:0043565sequence-specific DNA binding
0.61GO:0003700DNA binding transcription factor activity
0.39GO:0042803protein homodimerization activity
0.39GO:0046982protein heterodimerization activity
0.39GO:0001012RNA polymerase II regulatory region DNA binding
0.38GO:0003690double-stranded DNA binding
0.35GO:0003682chromatin binding
0.35GO:0046872metal ion binding
0.34GO:0043621protein self-association
0.61GO:0005634nucleus
0.35GO:0070013intracellular organelle lumen
0.34GO:0044446intracellular organelle part
sp|Q8IVH4|MMAA_HUMAN
Methylmalonic aciduria type A protein, mitochondrial
Search
MMAA
0.96Methylmalonic aciduria type A protein, mitochondrial
0.37GO:0009236cobalamin biosynthetic process
0.36GO:0019626short-chain fatty acid catabolic process
0.66GO:0003924GTPase activity
0.64GO:0032550purine ribonucleoside binding
0.64GO:0019001guanyl nucleotide binding
0.56GO:0042803protein homodimerization activity
0.53GO:0032555purine ribonucleotide binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0005739mitochondrion
0.34GO:0031974membrane-enclosed lumen
0.33GO:0044446intracellular organelle part
0.30GO:0031224intrinsic component of membrane
sp|Q8IVH8|M4K3_HUMAN
Mitogen-activated protein kinase kinase kinase kinase 3
Search
MAP4K3
0.82Mitogen-activated protein kinase kinase kinase kinase
0.85GO:0000185activation of MAPKKK activity
0.78GO:0000165MAPK cascade
0.56GO:0034612response to tumor necrosis factor
0.55GO:0009411response to UV
0.48GO:0031098stress-activated protein kinase signaling cascade
0.46GO:0007346regulation of mitotic cell cycle
0.45GO:0042981regulation of apoptotic process
0.85GO:0008349MAP kinase kinase kinase kinase activity
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0005515protein binding
0.45GO:0005622intracellular
0.30GO:0016020membrane
0.85EC:2.7.11 GO:0008349
sp|Q8IVI9|NOSTN_HUMAN
Nostrin
Search
NOSTRIN
0.93Nitric oxide synthase trafficking
0.66GO:0045892negative regulation of transcription, DNA-templated
0.54GO:0072011glomerular endothelium development
0.52GO:0072015glomerular visceral epithelial cell development
0.52GO:0097205renal filtration
0.51GO:0051489regulation of filopodium assembly
0.51GO:0002040sprouting angiogenesis
0.47GO:0006897endocytosis
0.43GO:0050999regulation of nitric-oxide synthase activity
0.34GO:0035023regulation of Rho protein signal transduction
0.33GO:0035556intracellular signal transduction
0.52GO:0003677DNA binding
0.40GO:0005515protein binding
0.34GO:0005509calcium ion binding
0.33GO:0098772molecular function regulator
0.33GO:0004435phosphatidylinositol phospholipase C activity
0.32GO:0004871signal transducer activity
0.74GO:0016607nuclear speck
0.47GO:0031410cytoplasmic vesicle
0.46GO:0005856cytoskeleton
0.40GO:0005886plasma membrane
0.40GO:0012506vesicle membrane
0.39GO:0098805whole membrane
0.39GO:0098588bounding membrane of organelle
0.30GO:0031224intrinsic component of membrane
0.33EC:3.1.4.11 GO:0004435
0.33KEGG:R03435 GO:0004435
sp|Q8IVJ1|S41A1_HUMAN
Solute carrier family 41 member 1
Search
SLC41A1
0.94Solute carrier family 41 (magnesium transporter), member 1
0.61GO:0098655cation transmembrane transport
0.61GO:0071286cellular response to magnesium ion
0.59GO:0010961cellular magnesium ion homeostasis
0.53GO:0015693magnesium ion transport
0.51GO:0006814sodium ion transport
0.46GO:0098660inorganic ion transmembrane transport
0.44GO:0048793pronephros development
0.42GO:0043009chordate embryonic development
0.62GO:0061768magnesium:sodium antiporter activity
0.54GO:0072509divalent inorganic cation transmembrane transporter activity
0.53GO:0015095magnesium ion transmembrane transporter activity
0.33GO:0003924GTPase activity
0.33GO:0001883purine nucleoside binding
0.33GO:0032561guanyl ribonucleotide binding
0.33GO:0032549ribonucleoside binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.55GO:0016323basolateral plasma membrane
0.44GO:0043234protein complex
0.30GO:0016021integral component of membrane
sp|Q8IVJ8|APRG1_HUMAN
AP20 region protein 1
Search
0.30AP20 region protein 1
0.30GO:0044425membrane part
sp|Q8IVK1|GLCM1_HUMAN
Putative glycosylation-dependent cell adhesion molecule 1
Search
0.37Putative glycosylation-dependent cell adhesion molecule 1
0.72GO:0050776regulation of immune response
0.55GO:0005886plasma membrane
sp|Q8IVL0|NAV3_HUMAN
Neuron navigator 3
Search
NAV3
0.96Neuron navigator 3
0.59GO:1905929positive regulation of invadopodium disassembly
0.56GO:0032703negative regulation of interleukin-2 production
0.55GO:0007026negative regulation of microtubule depolymerization
0.55GO:0031116positive regulation of microtubule polymerization
0.53GO:0030336negative regulation of cell migration
0.34GO:0072576liver morphogenesis
0.33GO:0031016pancreas development
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.49GO:0008017microtubule binding
0.33GO:0003779actin binding
0.55GO:1990752microtubule end
0.38GO:0005640nuclear outer membrane
0.33GO:0030175filopodium
0.33GO:0030027lamellipodium
0.33GO:0005794Golgi apparatus
sp|Q8IVL1|NAV2_HUMAN
Neuron navigator 2
Search
0.87Neuron navigator 2
0.72GO:0003025regulation of systemic arterial blood pressure by baroreceptor feedback
0.71GO:0021564vagus nerve development
0.71GO:0021563glossopharyngeal nerve development
0.69GO:0021554optic nerve development
0.64GO:0007605sensory perception of sound
0.64GO:0007626locomotory behavior
0.60GO:0007608sensory perception of smell
0.64GO:0008201heparin binding
0.48GO:0032559adenyl ribonucleotide binding
0.48GO:0008144drug binding
0.48GO:0035639purine ribonucleoside triphosphate binding
0.40GO:0004386helicase activity
0.39GO:0005515protein binding
0.36GO:0004427inorganic diphosphatase activity
0.69GO:0005614interstitial matrix
0.59GO:0005654nucleoplasm
0.36EC:3.6.1.1 GO:0004427
0.36KEGG:R00004 GO:0004427
sp|Q8IVL5|P3H2_HUMAN
Prolyl 3-hydroxylase 2
Search
P3H2
0.97Prolyl 3-hydroxylase 2
0.60GO:0018126protein hydroxylation
0.59GO:0032963collagen metabolic process
0.54GO:0008285negative regulation of cell proliferation
0.52GO:0018208peptidyl-proline modification
0.52GO:0055114oxidation-reduction process
0.45GO:1901874negative regulation of post-translational protein modification
0.43GO:0060348bone development
0.42GO:0050821protein stabilization
0.42GO:0050708regulation of protein secretion
0.40GO:0006457protein folding
0.77GO:0031418L-ascorbic acid binding
0.67GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.61GO:0005506iron ion binding
0.51GO:0051213dioxygenase activity
0.44GO:0140096catalytic activity, acting on a protein
0.35GO:0005518collagen binding
0.56GO:0005604basement membrane
0.52GO:0005783endoplasmic reticulum
0.50GO:0005794Golgi apparatus
0.41GO:0016528sarcoplasm
0.35GO:0070062extracellular exosome
0.35GO:0043233organelle lumen
0.34GO:0044446intracellular organelle part
0.33GO:0005634nucleus
0.33GO:0032991macromolecular complex
0.32GO:0005886plasma membrane
0.67EC:1.14 GO:0016705
sp|Q8IVL6|P3H3_HUMAN
Prolyl 3-hydroxylase 3
Search
P3H3
0.91Prolyl 3-hydroxylase 3
0.64GO:0032963collagen metabolic process
0.64GO:0017185peptidyl-lysine hydroxylation
0.58GO:0008285negative regulation of cell proliferation
0.52GO:0019511peptidyl-proline hydroxylation
0.51GO:0055114oxidation-reduction process
0.43GO:0009059macromolecule biosynthetic process
0.36GO:0007186G-protein coupled receptor signaling pathway
0.35GO:1901874negative regulation of post-translational protein modification
0.35GO:0060348bone development
0.34GO:0050821protein stabilization
0.76GO:0031418L-ascorbic acid binding
0.66GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.61GO:0005506iron ion binding
0.46GO:0051213dioxygenase activity
0.41GO:0140096catalytic activity, acting on a protein
0.36GO:0004930G-protein coupled receptor activity
0.34GO:0005515protein binding
0.48GO:1902494catalytic complex
0.46GO:0005783endoplasmic reticulum
0.38GO:0005604basement membrane
0.37GO:0005794Golgi apparatus
0.34GO:0016528sarcoplasm
0.33GO:0043233organelle lumen
0.32GO:0044446intracellular organelle part
0.30GO:0016020membrane
0.66EC:1.14 GO:0016705
sp|Q8IVL8|CBPO_HUMAN
Carboxypeptidase O
Search
CPO
0.97Carboxypeptidase O
0.60GO:0006508proteolysis
0.42GO:0002002regulation of angiotensin levels in blood
0.34GO:0042730fibrinolysis
0.76GO:0004181metallocarboxypeptidase activity
0.62GO:0008270zinc ion binding
0.56GO:0046658anchored component of plasma membrane
0.46GO:0044421extracellular region part
0.38GO:0016324apical plasma membrane
0.30GO:0016021integral component of membrane
0.76EC:3.4.17 GO:0004181
sp|Q8IVM0|CCD50_HUMAN
Coiled-coil domain-containing protein 50
Search
CCDC50
0.96Coiled-coil domain-containing protein 50
0.81GO:0007605sensory perception of sound
0.79GO:0031625ubiquitin protein ligase binding
0.68GO:0005829cytosol
0.59GO:0005874microtubule
0.30GO:0031224intrinsic component of membrane
sp|Q8IVM7|CM029_HUMAN
Putative uncharacterized protein encoded by LINC00346
Search
sp|Q8IVM8|S22A9_HUMAN
Solute carrier family 22 member 9
Search
0.97Solute carrier family 22 member 9
0.60GO:0043252sodium-independent organic anion transport
0.60GO:0015747urate transport
0.54GO:0055085transmembrane transport
0.51GO:0015913short-chain fatty acid import
0.49GO:0015698inorganic anion transport
0.46GO:0009914hormone transport
0.39GO:1901998toxin transport
0.36GO:0046415urate metabolic process
0.60GO:0015143urate transmembrane transporter activity
0.60GO:0015347sodium-independent organic anion transmembrane transporter activity
0.55GO:0005452inorganic anion exchanger activity
0.51GO:0015636short-chain fatty acid transmembrane transporter activity
0.46GO:0015301anion:anion antiporter activity
0.39GO:0019534toxin transmembrane transporter activity
0.48GO:0005887integral component of plasma membrane
0.46GO:0016323basolateral plasma membrane
0.38GO:0016324apical plasma membrane
0.35GO:0009897external side of plasma membrane
sp|Q8IVN3|MSTN1_HUMAN
Musculoskeletal embryonic nuclear protein 1
Search
MUSTN1
0.97Musculoskeletal embryonic nuclear protein 1
0.86GO:0035988chondrocyte proliferation
0.85GO:0002062chondrocyte differentiation
0.85GO:0042246tissue regeneration
0.49GO:1902730positive regulation of proteoglycan biosynthetic process
0.49GO:1902732positive regulation of chondrocyte proliferation
0.48GO:0032332positive regulation of chondrocyte differentiation
0.43GO:0010628positive regulation of gene expression
0.40GO:0030326embryonic limb morphogenesis
0.61GO:0005634nucleus
0.37GO:0043233organelle lumen
0.35GO:0044446intracellular organelle part
sp|Q8IVN8|SBSPO_HUMAN
Somatomedin-B and thrombospondin type-1 domain-containing protein
Search
SBSPON
0.96Somatomedin B and thrombospondin type 1 domain containing
0.73GO:0006955immune response
0.71GO:0006898receptor-mediated endocytosis
0.35GO:0050778positive regulation of immune response
0.35GO:0072376protein activation cascade
0.35GO:0002252immune effector process
0.33GO:0010951negative regulation of endopeptidase activity
0.33GO:0010935regulation of macrophage cytokine production
0.33GO:0032760positive regulation of tumor necrosis factor production
0.33GO:0032755positive regulation of interleukin-6 production
0.33GO:0006952defense response
0.80GO:0005044scavenger receptor activity
0.77GO:0001871pattern binding
0.69GO:0030246carbohydrate binding
0.33GO:0004867serine-type endopeptidase inhibitor activity
0.33GO:0008107galactoside 2-alpha-L-fucosyltransferase activity
0.33GO:0003823antigen binding
0.33GO:0001530lipopolysaccharide binding
0.32GO:0004843thiol-dependent ubiquitin-specific protease activity
0.32GO:0005509calcium ion binding
0.60GO:0031012extracellular matrix
0.35GO:0005579membrane attack complex
0.32GO:0005615extracellular space
0.33EC:2.4.1.69 GO:0008107
sp|Q8IVP5|FUND1_HUMAN
FUN14 domain-containing protein 1
Search
FUNDC1
0.96FUN14 domain-containing protein 1
0.81GO:0061726mitochondrion disassembly
0.74GO:0006914autophagy
0.73GO:0001666response to hypoxia
0.42GO:0010243response to organonitrogen compound
0.37GO:0005515protein binding
0.79GO:0031307integral component of mitochondrial outer membrane
0.34GO:0005634nucleus
sp|Q8IVP9|ZN547_HUMAN
Zinc finger protein 547
Search
ZNF416
0.84Zinc finger protein 416
0.56GO:1903506regulation of nucleic acid-templated transcription
0.56GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.39GO:0006351transcription, DNA-templated
0.35GO:0006468protein phosphorylation
0.34GO:1902679negative regulation of RNA biosynthetic process
0.52GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.36GO:0003700DNA binding transcription factor activity
0.35GO:0004672protein kinase activity
0.34GO:0032559adenyl ribonucleotide binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.45GO:0005622intracellular
0.38GO:0043227membrane-bounded organelle
sp|Q8IVQ6|ZDH21_HUMAN
Palmitoyltransferase ZDHHC21
Search
ZDHHC21
0.55Palmitoyltransferase
0.65GO:0018231peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.64GO:0048733sebaceous gland development
0.62GO:0018345protein palmitoylation
0.59GO:0001942hair follicle development
0.36GO:0050999regulation of nitric-oxide synthase activity
0.79GO:0019706protein-cysteine S-palmitoyltransferase activity
0.36GO:0004792thiosulfate sulfurtransferase activity
0.53GO:0005794Golgi apparatus
0.45GO:0005886plasma membrane
0.34GO:0098588bounding membrane of organelle
0.34GO:0031984organelle subcompartment
0.32GO:0005783endoplasmic reticulum
0.30GO:0031224intrinsic component of membrane
0.79EC:2.3.1.225 GO:0019706
0.36KEGG:R01931 GO:0004792
sp|Q8IVS2|FABD_HUMAN
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
Search
MCAT
0.44Malonyl-CoA-acyl carrier protein transacylase
0.63GO:0042967acyl-carrier-protein biosynthetic process
0.52GO:0006633fatty acid biosynthetic process
0.35GO:0006635fatty acid beta-oxidation
0.35GO:0005975carbohydrate metabolic process
0.31GO:0055085transmembrane transport
0.57GO:0004314[acyl-carrier-protein] S-malonyltransferase activity
0.35GO:0016773phosphotransferase activity, alcohol group as acceptor
0.34GO:0003723RNA binding
0.32GO:0042626ATPase activity, coupled to transmembrane movement of substances
0.31GO:0032559adenyl ribonucleotide binding
0.31GO:0008144drug binding
0.31GO:0035639purine ribonucleoside triphosphate binding
0.47GO:0005739mitochondrion
0.34GO:0031974membrane-enclosed lumen
0.33GO:0044446intracellular organelle part
0.30GO:0016020membrane
0.57EC:2.3.1.39 GO:0004314
sp|Q8IVS8|GLCTK_HUMAN
Glycerate kinase
Search
GLYCTK
0.50Glycerate kinase
0.56GO:0016310phosphorylation
0.48GO:0036211protein modification process
0.45GO:0044267cellular protein metabolic process
0.38GO:0061624fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
0.36GO:0003341cilium movement
0.60GO:0008887glycerate kinase activity
0.37GO:0032559adenyl ribonucleotide binding
0.36GO:0008144drug binding
0.36GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0003777microtubule motor activity
0.34GO:0005515protein binding
0.33GO:0016887ATPase activity
0.53GO:0005794Golgi apparatus
0.51GO:0005829cytosol
0.36GO:0005858axonemal dynein complex
0.36GO:0005739mitochondrion
0.33GO:0005581collagen trimer
0.60EC:2.7.1.31 GO:0008887
0.60KEGG:R01514 GO:0008887
sp|Q8IVT2|MISP_HUMAN
Mitotic interactor and substrate of PLK1
Search
MISP
0.96Mitotic spindle positioning
0.46GO:0051301cell division
0.46GO:0007049cell cycle
0.38GO:0006397mRNA processing
0.32GO:0008360regulation of cell shape
0.48GO:0003779actin binding
0.36GO:0003723RNA binding
0.81GO:0005925focal adhesion
0.55GO:0043231intracellular membrane-bounded organelle
0.54GO:0071944cell periphery
0.49GO:0099568cytoplasmic region
0.46GO:0005856cytoskeleton
0.30GO:0016020membrane
sp|Q8IVT5|KSR1_HUMAN
Kinase suppressor of Ras 1
Search
KSR1
0.93Kinase suppressor of Ras 1
0.63GO:0006468protein phosphorylation
0.62GO:0035556intracellular signal transduction
0.58GO:0043410positive regulation of MAPK cascade
0.64GO:0004672protein kinase activity
0.62GO:0031434mitogen-activated protein kinase kinase binding
0.62GO:0005078MAP-kinase scaffold activity
0.62GO:007188914-3-3 protein binding
0.61GO:0051879Hsp90 protein binding
0.58GO:0008022protein C-terminus binding
0.55GO:0051087chaperone binding
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0005783endoplasmic reticulum
0.46GO:0043234protein complex
0.38GO:0032587ruffle membrane
0.36GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.36GO:0031984organelle subcompartment
0.35GO:0005829cytosol
0.30GO:0016021integral component of membrane
sp|Q8IVU1|IGDC3_HUMAN
Immunoglobulin superfamily DCC subclass member 3
Search
IGDCC3
0.80Neural cell adhesion molecule 1
0.59GO:0050885neuromuscular process controlling balance
0.50GO:0007275multicellular organism development
0.40GO:0038007netrin-activated signaling pathway
0.39GO:0120039plasma membrane bounded cell projection morphogenesis
0.39GO:0000904cell morphogenesis involved in differentiation
0.39GO:0006915apoptotic process
0.39GO:0120036plasma membrane bounded cell projection organization
0.38GO:0006935chemotaxis
0.37GO:0006928movement of cell or subcellular component
0.33GO:0045663positive regulation of myoblast differentiation
0.40GO:0005042netrin receptor activity
0.32GO:0042802identical protein binding
0.49GO:0005887integral component of plasma membrane
sp|Q8IVU3|HERC6_HUMAN
Probable E3 ubiquitin-protein ligase HERC6
Search
HERC6
0.94HECT and RLD domain containing E3 ubiquitin protein ligase 5
0.73GO:0016567protein ubiquitination
0.57GO:0032020ISG15-protein conjugation
0.54GO:0050688regulation of defense response to virus
0.46GO:0002244hematopoietic progenitor cell differentiation
0.74GO:0004842ubiquitin-protein transferase activity
0.57GO:0042296ISG15 transferase activity
0.54GO:0061659ubiquitin-like protein ligase activity
0.34GO:0016874ligase activity
0.57GO:0005829cytosol
0.49GO:0005634nucleus
0.30GO:0044425membrane part
0.34EC:6 GO:0016874
0.74KEGG:R03876 GO:0004842
sp|Q8IVU9|CJ107_HUMAN
Uncharacterized protein C10orf107
Search
CABCOCO1
0.92Ciliary-associated calcium-binding coiled-coil protein 1
0.40GO:0015074DNA integration
0.38GO:0006508proteolysis
0.62GO:0005509calcium ion binding
0.41GO:0070001aspartic-type peptidase activity
0.39GO:0004175endopeptidase activity
0.36GO:0003676nucleic acid binding
0.74GO:0036126sperm flagellum
0.69GO:0005813centrosome
0.46GO:0005737cytoplasm
0.38GO:0043231intracellular membrane-bounded organelle
0.30GO:0031224intrinsic component of membrane
sp|Q8IVV2|LOXH1_HUMAN
Lipoxygenase homology domain-containing protein 1
Search
0.54Lipoxygenase homology domain-containing protein 1
0.69GO:0098869cellular oxidant detoxification
0.53GO:0055114oxidation-reduction process
0.46GO:0050982detection of mechanical stimulus
0.43GO:0070588calcium ion transmembrane transport
0.43GO:0007605sensory perception of sound
0.77GO:0004096catalase activity
0.63GO:0020037heme binding
0.44GO:0005262calcium channel activity
0.44GO:0032420stereocilium
0.30GO:0016020membrane
0.77EC:1.11.1.6 GO:0004096
sp|Q8IVV7|GID4_HUMAN
Glucose-induced degradation protein 4 homolog
Search
GID4
0.97GID complex subunit 4
0.78GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process
0.73GO:0016567protein ubiquitination
0.76GO:0061630ubiquitin protein ligase activity
sp|Q8IVV8|NKAI4_HUMAN
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4
Search
NKAIN4
0.97Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4
0.50GO:0002028regulation of sodium ion transport
0.32GO:0003723RNA binding
0.38GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IVW1|ARL17_HUMAN
ADP-ribosylation factor-like protein 17
Search
0.95ADP-ribosylation factor-like protein 17
0.36GO:0016192vesicle-mediated transport
0.35GO:0008104protein localization
0.35GO:0042886amide transport
0.34GO:0071702organic substance transport
0.34GO:0040007growth
0.34GO:0007163establishment or maintenance of cell polarity
0.34GO:0010513positive regulation of phosphatidylinositol biosynthetic process
0.34GO:0051641cellular localization
0.34GO:1903047mitotic cell cycle process
0.33GO:0016055Wnt signaling pathway
0.66GO:0005525GTP binding
0.33GO:0005102receptor binding
0.33GO:0003729mRNA binding
0.33GO:0016868intramolecular transferase activity, phosphotransferases
0.33GO:0016301kinase activity
0.33GO:0030234enzyme regulator activity
0.33GO:0003924GTPase activity
0.32GO:0004412homoserine dehydrogenase activity
0.32GO:0000287magnesium ion binding
0.32GO:0016773phosphotransferase activity, alcohol group as acceptor
0.44GO:0005622intracellular
0.37GO:0012505endomembrane system
0.35GO:0043227membrane-bounded organelle
0.33GO:0005934cellular bud tip
0.33GO:0005935cellular bud neck
0.33GO:0005578proteinaceous extracellular matrix
0.32GO:0005615extracellular space
0.32GO:0031975envelope
0.32GO:0044422organelle part
0.32GO:0005886plasma membrane
0.33EC:5.4.2 GO:0016868
sp|Q8IVW4|CDKL3_HUMAN
Cyclin-dependent kinase-like 3
Search
CDKL3
0.95Cyclin dependent kinase like 3
0.63GO:0006468protein phosphorylation
0.51GO:0097484dendrite extension
0.51GO:0050775positive regulation of dendrite morphogenesis
0.50GO:0030517negative regulation of axon extension
0.49GO:0051726regulation of cell cycle
0.36GO:1903955positive regulation of protein targeting to mitochondrion
0.34GO:0006470protein dephosphorylation
0.34GO:0007548sex differentiation
0.33GO:0043043peptide biosynthetic process
0.33GO:0010467gene expression
0.63GO:0004672protein kinase activity
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.45GO:0060089molecular transducer activity
0.34GO:0005515protein binding
0.34GO:0004721phosphoprotein phosphatase activity
0.34GO:0003735structural constituent of ribosome
0.32GO:0008270zinc ion binding
0.32GO:0003677DNA binding
0.46GO:0005634nucleus
0.45GO:0005813centrosome
0.35GO:0005737cytoplasm
0.33GO:0030529intracellular ribonucleoprotein complex
0.30GO:0031224intrinsic component of membrane
0.34EC:3.1.3.16 GO:0004721
sp|Q8IVW6|ARI3B_HUMAN
AT-rich interactive domain-containing protein 3B
Search
ARID3B
0.96AT-rich interactive domain-containing protein 3B
0.55GO:0006366transcription by RNA polymerase II
0.54GO:0045944positive regulation of transcription by RNA polymerase II
0.34GO:0007275multicellular organism development
0.62GO:0001205transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.60GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding
0.58GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
0.34GO:0005515protein binding
0.60GO:0005634nucleus
0.50GO:0031974membrane-enclosed lumen
0.45GO:0044446intracellular organelle part
sp|Q8IVW8|SPNS2_HUMAN
Protein spinster homolog 2
Search
SPNS2
0.97Sphingolipid transporter 2
0.59GO:0003376sphingosine-1-phosphate signaling pathway
0.57GO:0048073regulation of eye pigmentation
0.55GO:0048535lymph node development
0.55GO:0001782B cell homeostasis
0.55GO:0043029T cell homeostasis
0.55GO:0072676lymphocyte migration
0.55GO:0055085transmembrane transport
0.54GO:0002920regulation of humoral immune response
0.53GO:0060348bone development
0.52GO:0006869lipid transport
0.60GO:0046624sphingolipid transporter activity
0.48GO:0005765lysosomal membrane
0.45GO:0031982vesicle
0.33GO:0031966mitochondrial membrane
0.33GO:0019866organelle inner membrane
0.30GO:0016021integral component of membrane
sp|Q8IVY1|CA210_HUMAN
Type III endosome membrane protein TEMP
Search
0.97Type III endosome membrane protein TEMP
0.60GO:0055037recycling endosome
0.59GO:0005769early endosome
0.45GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IW00|VSTM4_HUMAN
V-set and transmembrane domain-containing protein 4
Search
VSTM4
0.97V-set and transmembrane domain-containing protein 4
0.40GO:0005886plasma membrane
0.36GO:0005576extracellular region
0.30GO:0044425membrane part
sp|Q8IW03|SIAH3_HUMAN
Seven in absentia homolog 3
Search
SIAH3
0.53E3 ubiquitin-protein ligase
0.78GO:1903215negative regulation of protein targeting to mitochondrion
0.73GO:0006511ubiquitin-dependent protein catabolic process
0.73GO:0016567protein ubiquitination
0.70GO:0007275multicellular organism development
0.67GO:0031647regulation of protein stability
0.54GO:0046872metal ion binding
0.34GO:0016874ligase activity
0.61GO:0005634nucleus
0.53GO:0005739mitochondrion
0.34EC:6 GO:0016874
sp|Q8IW19|APLF_HUMAN
Aprataxin and PNK-like factor
Search
APLF
0.93Aprataxin and PNKP like factor
0.87GO:0051106positive regulation of DNA ligation
0.86GO:0000012single strand break repair
0.76GO:0006302double-strand break repair
0.64GO:0090305nucleic acid phosphodiester bond hydrolysis
0.62GO:0045191regulation of isotype switching
0.77GO:0003906DNA-(apurinic or apyrimidinic site) lyase activity
0.72GO:00084083'-5' exonuclease activity
0.72GO:0004520endodeoxyribonuclease activity
0.53GO:1901265nucleoside phosphate binding
0.51GO:0036094small molecule binding
0.39GO:0046872metal ion binding
0.38GO:0005515protein binding
0.82GO:0035861site of double-strand break
0.69GO:0005654nucleoplasm
0.44GO:0005829cytosol
0.77EC:4.2.99.18 GO:0003906
sp|Q8IW35|CEP97_HUMAN
Centrosomal protein of 97 kDa
Search
CEP97
0.83Centrosomal protein of
0.86GO:1902018negative regulation of cilium assembly
0.85GO:1901673regulation of mitotic spindle assembly
0.43GO:0097711ciliary basal body-plasma membrane docking
0.40GO:0005516calmodulin binding
0.77GO:0005813centrosome
0.68GO:0005829cytosol
0.59GO:0043234protein complex
0.30GO:0016020membrane
sp|Q8IW36|ZN695_HUMAN
Zinc finger protein 695
Search
0.76Zinc finger protein 695
0.56GO:1903506regulation of nucleic acid-templated transcription
0.56GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.41GO:0006351transcription, DNA-templated
0.52GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.37GO:0003700DNA binding transcription factor activity
0.30GO:0005515protein binding
0.45GO:0005622intracellular
0.40GO:0043227membrane-bounded organelle
0.39GO:0043230extracellular organelle
0.38GO:0005615extracellular space
0.36GO:0031974membrane-enclosed lumen
0.35GO:0043228non-membrane-bounded organelle
0.35GO:0044422organelle part
sp|Q8IW40|CC103_HUMAN
Coiled-coil domain-containing protein 103
Search
CCDC103
0.97Coiled-coil domain-containing protein 103
0.83GO:0070286axonemal dynein complex assembly
0.82GO:0001947heart looping
0.81GO:0003341cilium movement
0.75GO:0071907determination of digestive tract left/right asymmetry
0.66GO:0003146heart jogging
0.63GO:0042803protein homodimerization activity
0.72GO:0005929cilium
0.69GO:0032838plasma membrane bounded cell projection cytoplasm
0.60GO:0044430cytoskeletal part
0.30GO:0031224intrinsic component of membrane
sp|Q8IW41|MAPK5_HUMAN
MAP kinase-activated protein kinase 5
Search
MAPKAPK5
0.97Mitogen-activated protein kinase-activated protein kinase 5
0.63GO:0006468protein phosphorylation
0.55GO:0090400stress-induced premature senescence
0.54GO:0007265Ras protein signal transduction
0.54GO:1904355positive regulation of telomere capping
0.53GO:0051973positive regulation of telomerase activity
0.53GO:0032212positive regulation of telomere maintenance via telomerase
0.48GO:0032007negative regulation of TOR signaling
0.47GO:0006417regulation of translation
0.46GO:0018209peptidyl-serine modification
0.43GO:0007166cell surface receptor signaling pathway
0.64GO:0004672protein kinase activity
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.53GO:0002039p53 binding
0.50GO:0051019mitogen-activated protein kinase binding
0.46GO:0005516calmodulin binding
0.41GO:0004871signal transducer activity
0.34GO:0016620oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34GO:0016627oxidoreductase activity, acting on the CH-CH group of donors
0.46GO:0005654nucleoplasm
0.45GO:0005829cytosol
0.40GO:0032156septin cytoskeleton
0.36GO:0043234protein complex
0.30GO:0016020membrane
0.34EC:1.2.1 GO:0016620
sp|Q8IW45|NNRD_HUMAN
ATP-dependent (S)-NAD(P)H-hydrate dehydratase
Search
CARKD
0.75ATP-dependent (S)-NAD(P)H-hydrate dehydratase
0.62GO:0019362pyridine nucleotide metabolic process
0.39GO:0016310phosphorylation
0.34GO:0072525pyridine-containing compound biosynthetic process
0.34GO:0009108coenzyme biosynthetic process
0.33GO:0009165nucleotide biosynthetic process
0.80GO:0047453ATP-dependent NAD(P)H-hydrate dehydratase activity
0.78GO:0052855ADP-dependent NAD(P)H-hydrate dehydratase activity
0.52GO:0032559adenyl ribonucleotide binding
0.51GO:0008144drug binding
0.51GO:0035639purine ribonucleoside triphosphate binding
0.40GO:0016301kinase activity
0.33GO:0005515protein binding
0.50GO:0005739mitochondrion
0.35GO:0005783endoplasmic reticulum
0.35GO:0005829cytosol
0.34GO:0031974membrane-enclosed lumen
0.33GO:0044446intracellular organelle part
0.30GO:0031224intrinsic component of membrane
0.80EC:4.2.1.93 GO:0047453
0.80KEGG:R00129 GO:0047453
sp|Q8IW50|F219A_HUMAN
Protein FAM219A
Search
sp|Q8IW52|SLIK4_HUMAN
SLIT and NTRK-like protein 4
Search
SLITRK4
0.97SLIT and NTRK like family member 4
0.53GO:0007409axonogenesis
0.53GO:0051965positive regulation of synapse assembly
0.35GO:0007625grooming behavior
0.35GO:0021756striatum development
0.35GO:0048813dendrite morphogenesis
0.34GO:0043588skin development
0.34GO:0030534adult behavior
0.34GO:0072358cardiovascular system development
0.34GO:0007268chemical synaptic transmission
0.34GO:0009410response to xenobiotic stimulus
0.33GO:0005515protein binding
0.37GO:0043235receptor complex
0.33GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IW70|T151B_HUMAN
Transmembrane protein 151B
Search
TMEM151B
0.91LOW QUALITY PROTEIN: transmembrane protein 151B
0.30GO:0044425membrane part
sp|Q8IW75|SPA12_HUMAN
Serpin A12
Search
SERPINA12
0.72Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
0.63GO:0046628positive regulation of insulin receptor signaling pathway
0.62GO:0090181regulation of cholesterol metabolic process
0.61GO:0090207regulation of triglyceride metabolic process
0.60GO:0014068positive regulation of phosphatidylinositol 3-kinase signaling
0.60GO:0045721negative regulation of gluconeogenesis
0.59GO:0051055negative regulation of lipid biosynthetic process
0.57GO:0010951negative regulation of endopeptidase activity
0.54GO:2000266regulation of blood coagulation, intrinsic pathway
0.38GO:0002438acute inflammatory response to antigenic stimulus
0.37GO:0007595lactation
0.59GO:0004867serine-type endopeptidase inhibitor activity
0.50GO:0008201heparin binding
0.46GO:0002020protease binding
0.43GO:0042802identical protein binding
0.36GO:0005496steroid binding
0.35GO:0003730mRNA 3'-UTR binding
0.34GO:0008233peptidase activity
0.33GO:0046872metal ion binding
0.32GO:0016874ligase activity
0.73GO:0005615extracellular space
0.44GO:0005886plasma membrane
0.35GO:0005783endoplasmic reticulum
0.35GO:0005794Golgi apparatus
0.34GO:1903561extracellular vesicle
0.32GO:0043233organelle lumen
0.32GO:0044446intracellular organelle part
0.30GO:0016021integral component of membrane
0.34EC:3.4 GO:0008233
sp|Q8IW92|GLBL2_HUMAN
Beta-galactosidase-1-like protein 2
Search
GLB1L2
0.41Beta-galactosidase
0.60GO:0005975carbohydrate metabolic process
0.36GO:0060271cilium assembly
0.77GO:0004565beta-galactosidase activity
0.47GO:0005773vacuole
0.37GO:0097546ciliary base
0.35GO:0005576extracellular region
0.30GO:0031224intrinsic component of membrane
0.77EC:3.2.1.23 GO:0004565
sp|Q8IW93|ARHGJ_HUMAN
Rho guanine nucleotide exchange factor 19
Search
ARHGEF19
0.95Rho guanine nucleotide exchange factor 5
0.75GO:0035023regulation of Rho protein signal transduction
0.64GO:0065009regulation of molecular function
0.56GO:0032956regulation of actin cytoskeleton organization
0.55GO:0042060wound healing
0.47GO:0002408myeloid dendritic cell chemotaxis
0.47GO:0035556intracellular signal transduction
0.47GO:0071803positive regulation of podosome assembly
0.45GO:1904591positive regulation of protein import
0.45GO:0046330positive regulation of JNK cascade
0.44GO:1902905positive regulation of supramolecular fiber organization
0.76GO:0005089Rho guanyl-nucleotide exchange factor activity
0.38GO:0005096GTPase activator activity
0.34GO:0008289lipid binding
0.33GO:0032550purine ribonucleoside binding
0.33GO:0019001guanyl nucleotide binding
0.32GO:0032555purine ribonucleotide binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.42GO:0005829cytosol
0.42GO:0005654nucleoplasm
0.38GO:0005886plasma membrane
0.36GO:0002102podosome
0.35GO:0030054cell junction
0.34GO:0042995cell projection
sp|Q8IWA0|WDR75_HUMAN
WD repeat-containing protein 75
Search
WDR75
0.92WD repeat-containing protein 75
0.85GO:2000234positive regulation of rRNA processing
0.82GO:1903146regulation of autophagy of mitochondrion
0.81GO:0045943positive regulation of transcription by RNA polymerase I
0.81GO:1903955positive regulation of protein targeting to mitochondrion
0.41GO:0006364rRNA processing
0.38GO:0006351transcription, DNA-templated
0.38GO:0032559adenyl ribonucleotide binding
0.38GO:0003723RNA binding
0.38GO:0008144drug binding
0.38GO:0035639purine ribonucleoside triphosphate binding
0.30GO:0003824catalytic activity
0.70GO:0005730nucleolus
0.37GO:0005654nucleoplasm
sp|Q8IWA4|MFN1_HUMAN
Mitofusin-1
Search
MFN1
0.91Mitochondrial transmembrane GTPase FZO-2
0.85GO:0008053mitochondrial fusion
0.51GO:0048662negative regulation of smooth muscle cell proliferation
0.49GO:0051646mitochondrion localization
0.42GO:0007006mitochondrial membrane organization
0.41GO:1905461positive regulation of vascular associated smooth muscle cell apoptotic process
0.41GO:0061734parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
0.41GO:1904707positive regulation of vascular smooth muscle cell proliferation
0.40GO:0034497protein localization to phagophore assembly site
0.40GO:0046580negative regulation of Ras protein signal transduction
0.40GO:0001825blastocyst formation
0.68GO:0003924GTPase activity
0.66GO:0005525GTP binding
0.39GO:0031625ubiquitin protein ligase binding
0.34GO:0042803protein homodimerization activity
0.33GO:0003676nucleic acid binding
0.78GO:0005741mitochondrial outer membrane
0.46GO:0098573intrinsic component of mitochondrial membrane
0.37GO:0015630microtubule cytoskeleton
0.37GO:0031301integral component of organelle membrane
0.36GO:0098798mitochondrial protein complex
0.36GO:1904115axon cytoplasm
0.35GO:0098796membrane protein complex
0.34GO:0005829cytosol
0.33GO:0005743mitochondrial inner membrane
sp|Q8IWA5|CTL2_HUMAN
Choline transporter-like protein 2
Search
SLC44A2
0.93LOW QUALITY PROTEIN: choline transporter-like protein 2
0.37GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35GO:0043312neutrophil degranulation
0.35GO:0006656phosphatidylcholine biosynthetic process
0.35GO:0015871choline transport
0.34GO:0007165signal transduction
0.33GO:0055085transmembrane transport
0.35GO:0015220choline transmembrane transporter activity
0.34GO:0004871signal transducer activity
0.34GO:0003725double-stranded RNA binding
0.33GO:0005515protein binding
0.36GO:0005765lysosomal membrane
0.36GO:0070062extracellular exosome
0.36GO:0035579specific granule membrane
0.33GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IWA6|CCD60_HUMAN
Coiled-coil domain-containing protein 60
Search
CCDC60
0.96Coiled-coil domain-containing protein 60
0.52GO:0009607response to biotic stimulus
0.51GO:0005515protein binding
0.30GO:0044425membrane part
sp|Q8IWB1|IPRI_HUMAN
Inositol 1,4,5-trisphosphate receptor-interacting protein
Search
ITPRIP
0.97Inositol 1,4,5-trisphosphate receptor-interacting protein (Fragment)
0.63GO:1902042negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.59GO:0006469negative regulation of protein kinase activity
0.60GO:0004860protein kinase inhibitor activity
0.50GO:0005515protein binding
0.49GO:0005886plasma membrane
0.45GO:0005576extracellular region
0.30GO:0044425membrane part
sp|Q8IWB4|S31A7_HUMAN
Spermatogenesis-associated protein 31A7
Search
0.97Spermatogenesis-associated protein 31A7
0.60GO:0007283spermatogenesis
0.55GO:0030154cell differentiation
0.30GO:0044425membrane part
sp|Q8IWB6|TEX14_HUMAN
Inactive serine/threonine-protein kinase TEX14
Search
TEX14
0.88Testis expressed 14, intercellular bridge forming factor
0.69GO:0043063intercellular bridge organization
0.68GO:0051306mitotic sister chromatid separation
0.65GO:0007140male meiotic nuclear division
0.64GO:0032091negative regulation of protein binding
0.64GO:0032466negative regulation of cytokinesis
0.64GO:1990823response to leukemia inhibitory factor
0.64GO:0008608attachment of spindle microtubules to kinetochore
0.63GO:0006468protein phosphorylation
0.63GO:0007094mitotic spindle assembly checkpoint
0.60GO:0071345cellular response to cytokine stimulus
0.64GO:0004672protein kinase activity
0.60GO:0019901protein kinase binding
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.65GO:0045171intercellular bridge
0.64GO:0030496midbody
0.61GO:0000776kinetochore
0.42GO:0000779condensed chromosome, centromeric region
0.39GO:0070062extracellular exosome
0.35GO:0005737cytoplasm
sp|Q8IWB7|WDFY1_HUMAN
WD repeat and FYVE domain-containing protein 1
Search
WDFY1
0.96WD repeat and FYVE domain-containing protein 1
0.58GO:0034141positive regulation of toll-like receptor 3 signaling pathway
0.58GO:0034145positive regulation of toll-like receptor 4 signaling pathway
0.34GO:0006886intracellular protein transport
0.34GO:0016192vesicle-mediated transport
0.54GO:00055451-phosphatidylinositol binding
0.53GO:0046872metal ion binding
0.34GO:0005515protein binding
0.53GO:0005769early endosome
0.47GO:0005829cytosol
0.44GO:0005634nucleus
0.35GO:0030117membrane coat
sp|Q8IWB9|TEX2_HUMAN
Testis-expressed protein 2
Search
TEX2
0.95Testis expressed gene 2
0.36GO:0006397mRNA processing
0.36GO:0090501RNA phosphodiester bond hydrolysis
0.35GO:0006468protein phosphorylation
0.33GO:0006869lipid transport
0.30GO:0007165signal transduction
0.30GO:0006629lipid metabolic process
0.43GO:0008289lipid binding
0.36GO:0004540ribonuclease activity
0.35GO:0004672protein kinase activity
0.34GO:0032559adenyl ribonucleotide binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.43GO:0005783endoplasmic reticulum
0.30GO:0016020membrane
sp|Q8IWC1|MA7D3_HUMAN
MAP7 domain-containing protein 3
Search
MAP7D3
0.88MAP7 domain-containing protein 3
0.76GO:0000226microtubule cytoskeleton organization
0.53GO:0051258protein polymerization
0.51GO:0097435supramolecular fiber organization
0.34GO:0006413translational initiation
0.33GO:0072659protein localization to plasma membrane
0.33GO:0007163establishment or maintenance of cell polarity
0.33GO:0006970response to osmotic stress
0.33GO:0016192vesicle-mediated transport
0.51GO:0008017microtubule binding
0.40GO:0005198structural molecule activity
0.34GO:0003743translation initiation factor activity
0.33GO:0005102receptor binding
0.71GO:0015630microtubule cytoskeleton
0.39GO:0044430cytoskeletal part
0.38GO:0005829cytosol
0.33GO:0016323basolateral plasma membrane
0.33GO:0048471perinuclear region of cytoplasm
0.33GO:0099512supramolecular fiber
0.32GO:0043234protein complex
0.30GO:0016021integral component of membrane
sp|Q8IWD4|CC117_HUMAN
Coiled-coil domain-containing protein 117
Search
CCDC117
0.95Coiled-coil domain-containing protein 117
0.51GO:0051259protein oligomerization
0.51GO:0032781positive regulation of ATPase activity
0.49GO:0097428protein maturation by iron-sulfur cluster transfer
0.45GO:0043043peptide biosynthetic process
0.43GO:0044267cellular protein metabolic process
0.41GO:0009059macromolecule biosynthetic process
0.53GO:0005515protein binding
0.51GO:0001671ATPase activator activity
0.47GO:0003735structural constituent of ribosome
0.45GO:0005840ribosome
sp|Q8IWD5|MFS6L_HUMAN
Major facilitator superfamily domain-containing protein 6-like
Search
MFSD6L
0.83Major facilitator superfamily domain-containing protein 6
0.30GO:0044425membrane part
sp|Q8IWE2|NXP20_HUMAN
Protein NOXP20
Search
sp|Q8IWE4|DCNL3_HUMAN
DCN1-like protein 3
Search
sp|Q8IWE5|PKHM2_HUMAN
Pleckstrin homology domain-containing family M member 2
Search
PLEKHM2
0.95Pleckstrin like proteiny domain-containing family M member 2
0.87GO:1903527positive regulation of membrane tubulation
0.84GO:0032418lysosome localization
0.80GO:0007030Golgi organization
0.73GO:0032880regulation of protein localization
0.38GO:0006508proteolysis
0.84GO:0019894kinesin binding
0.40GO:0070001aspartic-type peptidase activity
0.39GO:0004175endopeptidase activity
0.76GO:0010008endosome membrane
0.30GO:0044425membrane part
sp|Q8IWF2|FXRD2_HUMAN
FAD-dependent oxidoreductase domain-containing protein 2
Search
FOXRED2
0.97FAD-dependent oxidoreductase domain-containing protein 2
0.76GO:0030433ubiquitin-dependent ERAD pathway
0.43GO:0006662glycerol ether metabolic process
0.42GO:0045454cell redox homeostasis
0.42GO:0002191cap-dependent translational initiation
0.40GO:0001731formation of translation preinitiation complex
0.40GO:0006446regulation of translational initiation
0.39GO:0055114oxidation-reduction process
0.62GO:0050660flavin adenine dinucleotide binding
0.42GO:0015035protein disulfide oxidoreductase activity
0.42GO:0098808mRNA cap binding
0.39GO:0003743translation initiation factor activity
0.36GO:0005515protein binding
0.34GO:0004497monooxygenase activity
0.78GO:0005788endoplasmic reticulum lumen
0.40GO:0016282eukaryotic 43S preinitiation complex
0.40GO:0033290eukaryotic 48S preinitiation complex
0.40GO:0005852eukaryotic translation initiation factor 3 complex
0.30GO:0031224intrinsic component of membrane
sp|Q8IWF6|DEN6A_HUMAN
Protein DENND6A
Search
DENND6A
0.97DENN domain containing 6A
0.71GO:2000049positive regulation of cell-cell adhesion mediated by cadherin
0.66GO:0065009regulation of molecular function
0.85GO:0017112Rab guanyl-nucleotide exchange factor activity
0.67GO:0055037recycling endosome
0.47GO:0043231intracellular membrane-bounded organelle
sp|Q8IWF7|U2D2L_HUMAN
Putative ubiquitin-conjugating enzyme E2 D2-like protein
Search
0.51Ubiquitin conjugating enzyme E2 (Fragment)
0.43GO:0032446protein modification by small protein conjugation
0.43GO:1902916positive regulation of protein polyubiquitination
0.43GO:0006511ubiquitin-dependent protein catabolic process
0.40GO:0036503ERAD pathway
0.39GO:0030466chromatin silencing at silent mating-type cassette
0.36GO:0000022mitotic spindle elongation
0.35GO:0008283cell proliferation
0.35GO:0034314Arp2/3 complex-mediated actin nucleation
0.35GO:0031505fungal-type cell wall organization
0.34GO:0018205peptidyl-lysine modification
0.53GO:0032559adenyl ribonucleotide binding
0.52GO:0008144drug binding
0.52GO:0035639purine ribonucleoside triphosphate binding
0.46GO:0061650ubiquitin-like protein conjugating enzyme activity
0.43GO:0004842ubiquitin-protein transferase activity
0.38GO:0016874ligase activity
0.36GO:0005515protein binding
0.35GO:0061659ubiquitin-like protein ligase activity
0.35GO:0019789SUMO transferase activity
0.34GO:0016627oxidoreductase activity, acting on the CH-CH group of donors
0.41GO:0000151ubiquitin ligase complex
0.37GO:0043234protein complex
0.36GO:0005783endoplasmic reticulum
0.35GO:0005720nuclear heterochromatin
0.35GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.35GO:0000794condensed nuclear chromosome
0.35GO:0031984organelle subcompartment
0.34GO:0015629actin cytoskeleton
0.34GO:0044430cytoskeletal part
0.33GO:0005829cytosol
0.38EC:6 GO:0016874
0.43KEGG:R03876 GO:0004842
sp|Q8IWF9|CCD83_HUMAN
Coiled-coil domain-containing protein 83
Search
CCDC83
0.93Coiled-coil domain-containing protein 83
sp|Q8IWG1|WDR63_HUMAN
WD repeat-containing protein 63
Search
WDR63
0.97WD repeat-containing protein 63
0.74GO:0007018microtubule-based movement
0.86GO:0045504dynein heavy chain binding
0.86GO:0045503dynein light chain binding
0.85GO:0008574ATP-dependent microtubule motor activity, plus-end-directed
0.79GO:0030286dynein complex
0.85EC:3.6.4.4 GO:0008574
sp|Q8IWI9|MGAP_HUMAN
MAX gene-associated protein
Search
MGA
0.92MAX gene associated
0.57GO:2001141regulation of RNA biosynthetic process
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.56GO:0006351transcription, DNA-templated
0.43GO:1990830cellular response to leukemia inhibitory factor
0.40GO:0051254positive regulation of RNA metabolic process
0.40GO:0010557positive regulation of macromolecule biosynthetic process
0.40GO:0031328positive regulation of cellular biosynthetic process
0.40GO:0070317negative regulation of G0 to G1 transition
0.65GO:0046983protein dimerization activity
0.61GO:0003700DNA binding transcription factor activity
0.54GO:0003677DNA binding
0.41GO:0001067regulatory region nucleic acid binding
0.82GO:0071339MLL1 complex
0.41GO:0005667transcription factor complex
sp|Q8IWJ2|GCC2_HUMAN
GRIP and coiled-coil domain-containing protein 2
Search
GCC2
0.95GRIP and coiled-coil domain-containing protein 2
0.87GO:0071955recycling endosome to Golgi transport
0.86GO:0034499late endosome to Golgi transport
0.86GO:0090161Golgi ribbon formation
0.85GO:0006622protein targeting to lysosome
0.85GO:0070861regulation of protein exit from endoplasmic reticulum
0.83GO:0034067protein localization to Golgi apparatus
0.83GO:0034453microtubule anchoring
0.81GO:0031023microtubule organizing center organization
0.45GO:0043001Golgi to plasma membrane protein transport
0.34GO:0046604positive regulation of mitotic centrosome separation
0.73GO:0042802identical protein binding
0.34GO:0008536Ran GTPase binding
0.33GO:0005096GTPase activator activity
0.78GO:0005802trans-Golgi network
0.69GO:0005654nucleoplasm
0.67GO:0005829cytosol
0.33GO:0005643nuclear pore
0.33GO:0005813centrosome
0.30GO:0016020membrane
sp|Q8IWK6|AGRA3_HUMAN
Adhesion G protein-coupled receptor A3
Search
ADGRA3
0.95Adhesion G protein-coupled receptor A3
0.70GO:0007166cell surface receptor signaling pathway
0.70GO:0007186G-protein coupled receptor signaling pathway
0.37GO:0097475motor neuron migration
0.37GO:2000095regulation of Wnt signaling pathway, planar cell polarity pathway
0.37GO:0060027convergent extension involved in gastrulation
0.37GO:0003401axis elongation
0.36GO:0198738cell-cell signaling by wnt
0.71GO:0004930G-protein coupled receptor activity
0.35GO:0005515protein binding
0.67GO:0009897external side of plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IWL1|SFPA2_HUMAN
Pulmonary surfactant-associated protein A2
Search
SFTPA1
0.95Pulmonary surfactant-associated protein A
0.60GO:0007585respiratory gaseous exchange
0.53GO:0008228opsonization
0.46GO:0002253activation of immune response
0.43GO:0033189response to vitamin A
0.43GO:0071732cellular response to nitric oxide
0.42GO:0045089positive regulation of innate immune response
0.42GO:0002764immune response-regulating signaling pathway
0.42GO:0055093response to hyperoxia
0.42GO:0070741response to interleukin-6
0.42GO:0070849response to epidermal growth factor
0.53GO:0030246carbohydrate binding
0.47GO:0005201extracellular matrix structural constituent
0.41GO:0046872metal ion binding
0.39GO:0042302structural constituent of cuticle
0.38GO:0005319lipid transporter activity
0.36GO:0005515protein binding
0.35GO:0036094small molecule binding
0.34GO:0001540amyloid-beta binding
0.34GO:0008201heparin binding
0.33GO:0004867serine-type endopeptidase inhibitor activity
0.74GO:0005581collagen trimer
0.55GO:0005578proteinaceous extracellular matrix
0.54GO:0005615extracellular space
0.45GO:0042599lamellar body
0.43GO:0045334clathrin-coated endocytic vesicle
0.43GO:0005783endoplasmic reticulum
0.42GO:0005771multivesicular body
0.40GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.40GO:0044420extracellular matrix component
0.39GO:0031984organelle subcompartment
sp|Q8IWL2|SFTA1_HUMAN
Pulmonary surfactant-associated protein A1
Search
SFTPA1
0.95Pulmonary surfactant-associated protein A
0.56GO:0007585respiratory gaseous exchange
0.50GO:0008228opsonization
0.44GO:0002253activation of immune response
0.43GO:0035987endodermal cell differentiation
0.41GO:0033189response to vitamin A
0.41GO:0072376protein activation cascade
0.41GO:0071732cellular response to nitric oxide
0.41GO:0045089positive regulation of innate immune response
0.41GO:0055093response to hyperoxia
0.41GO:0002764immune response-regulating signaling pathway
0.52GO:0005201extracellular matrix structural constituent
0.50GO:0030246carbohydrate binding
0.40GO:0046872metal ion binding
0.40GO:0042302structural constituent of cuticle
0.39GO:0004867serine-type endopeptidase inhibitor activity
0.37GO:0005319lipid transporter activity
0.37GO:0005515protein binding
0.35GO:0036094small molecule binding
0.33GO:0004930G-protein coupled receptor activity
0.73GO:0005581collagen trimer
0.53GO:0031012extracellular matrix
0.53GO:0005615extracellular space
0.43GO:0042599lamellar body
0.41GO:0045334clathrin-coated endocytic vesicle
0.41GO:0005783endoplasmic reticulum
0.40GO:0005771multivesicular body
0.39GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.38GO:0031984organelle subcompartment
0.34GO:1903561extracellular vesicle
sp|Q8IWL3|HSC20_HUMAN
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial
Search
HSCB
0.95HscB mitochondrial iron-sulfur cluster co-chaperone
0.81GO:0032781positive regulation of ATPase activity
0.78GO:0097428protein maturation by iron-sulfur cluster transfer
0.72GO:0051259protein oligomerization
0.61GO:0031163metallo-sulfur cluster assembly
0.55GO:0006790sulfur compound metabolic process
0.53GO:0051188cofactor biosynthetic process
0.37GO:0006457protein folding
0.82GO:0001671ATPase activator activity
0.77GO:0051087chaperone binding
0.61GO:0042802identical protein binding
0.35GO:0046872metal ion binding
0.57GO:0005829cytosol
0.52GO:0005634nucleus
0.52GO:0005739mitochondrion
sp|Q8IWL8|STH_HUMAN
Saitohin
Search
0.64GO:0048026positive regulation of mRNA splicing, via spliceosome
0.49GO:0005515protein binding
0.61GO:0005634nucleus
0.59GO:0048471perinuclear region of cytoplasm
sp|Q8IWN6|F223A_HUMAN
Protein FAM223A
Search
sp|Q8IWN7|RP1L1_HUMAN
Retinitis pigmentosa 1-like 1 protein
Search
RP1L1
0.60Retinitis pigmentosa 1-like 1 protein (Fragment)
0.62GO:0035556intracellular signal transduction
0.55GO:0042461photoreceptor cell development
0.54GO:0035082axoneme assembly
0.54GO:0060041retina development in camera-type eye
0.47GO:0045494photoreceptor cell maintenance
0.45GO:0007601visual perception
0.34GO:0060026convergent extension
0.34GO:0021549cerebellum development
0.32GO:0060255regulation of macromolecule metabolic process
0.32GO:0051641cellular localization
0.32GO:0003676nucleic acid binding
0.32GO:0008995ribonuclease E activity
0.32GO:0000030mannosyltransferase activity
0.32GO:0004843thiol-dependent ubiquitin-specific protease activity
0.32GO:0003924GTPase activity
0.32GO:0005525GTP binding
0.32GO:0004521endoribonuclease activity
0.32GO:0000287magnesium ion binding
0.31GO:0008270zinc ion binding
0.53GO:0005930axoneme
0.47GO:0032391photoreceptor connecting cilium
0.47GO:0001750photoreceptor outer segment
0.46GO:0070062extracellular exosome
0.43GO:0005874microtubule
0.32GO:0099115chromosome, subtelomeric region
0.32GO:0044459plasma membrane part
0.32GO:0098562cytoplasmic side of membrane
0.32GO:0000781chromosome, telomeric region
0.32GO:0005730nucleolus
0.32EC:2.4.1 GO:0000030
sp|Q8IWP9|CC28A_HUMAN
Coiled-coil domain-containing protein 28A
Search
CCDC28A
0.96LOW QUALITY PROTEIN: coiled-coil domain-containing protein 28A
0.58GO:0060271cilium assembly
0.54GO:0035023regulation of Rho protein signal transduction
0.48GO:0065009regulation of molecular function
0.54GO:0005089Rho guanyl-nucleotide exchange factor activity
0.47GO:0005813centrosome
sp|Q8IWQ3|BRSK2_HUMAN
Serine/threonine-protein kinase BRSK2
Search
BRSK2
0.85BR serine/threonine-protein kinase 2
0.63GO:0006468protein phosphorylation
0.58GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.58GO:0061178regulation of insulin secretion involved in cellular response to glucose stimulus
0.57GO:0000086G2/M transition of mitotic cell cycle
0.55GO:0036503ERAD pathway
0.53GO:0030010establishment of cell polarity
0.53GO:0018209peptidyl-serine modification
0.53GO:0007409axonogenesis
0.53GO:0031532actin cytoskeleton reorganization
0.63GO:0004672protein kinase activity
0.57GO:0051117ATPase binding
0.54GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0019901protein kinase binding
0.47GO:0000287magnesium ion binding
0.57GO:0005813centrosome
0.49GO:0005783endoplasmic reticulum
0.42GO:0005634nucleus
sp|Q8IWR0|Z3H7A_HUMAN
Zinc finger CCCH domain-containing protein 7A
Search
ZC3H7A
0.97Zinc finger CCCH type-containing 7 A
0.63GO:0035196production of miRNAs involved in gene silencing by miRNA
0.64GO:0035198miRNA binding
0.53GO:0046872metal ion binding
0.34GO:0005634nucleus
sp|Q8IWR1|TRI59_HUMAN
Tripartite motif-containing protein 59
Search
TRIM59
0.86Tripartite motif-containing protein 59
0.57GO:0046597negative regulation of viral entry into host cell
0.56GO:0043122regulation of I-kappaB kinase/NF-kappaB signaling
0.54GO:0045087innate immune response
0.52GO:1902532negative regulation of intracellular signal transduction
0.51GO:0016567protein ubiquitination
0.50GO:0060271cilium assembly
0.41GO:1902187negative regulation of viral release from host cell
0.41GO:0032897negative regulation of viral transcription
0.41GO:0010332response to gamma radiation
0.40GO:0016239positive regulation of macroautophagy
0.62GO:0008270zinc ion binding
0.52GO:0004842ubiquitin-protein transferase activity
0.51GO:0061659ubiquitin-like protein ligase activity
0.37GO:0016874ligase activity
0.35GO:0005515protein binding
0.32GO:0043142single-stranded DNA-dependent ATPase activity
0.52GO:0030992intraciliary transport particle B
0.51GO:0005929cilium
0.50GO:0005783endoplasmic reticulum
0.49GO:0005813centrosome
0.41GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.40GO:0031984organelle subcompartment
0.39GO:0048471perinuclear region of cytoplasm
0.32GO:0097505Rad6-Rad18 complex
0.31GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
0.37EC:6 GO:0016874
0.52KEGG:R03876 GO:0004842
sp|Q8IWS0|PHF6_HUMAN
PHD finger protein 6
Search
0.56PHD finger protein 6
0.38GO:0007346regulation of mitotic cell cycle
0.36GO:0006468protein phosphorylation
0.35GO:0060255regulation of macromolecule metabolic process
0.30GO:0090304nucleic acid metabolic process
0.30GO:0009890negative regulation of biosynthetic process
0.30GO:0018130heterocycle biosynthetic process
0.30GO:1901362organic cyclic compound biosynthetic process
0.30GO:0048523negative regulation of cellular process
0.30GO:0019438aromatic compound biosynthetic process
0.30GO:0080090regulation of primary metabolic process
0.53GO:0046872metal ion binding
0.40GO:0004693cyclin-dependent protein serine/threonine kinase activity
0.35GO:0032559adenyl ribonucleotide binding
0.35GO:0008144drug binding
0.35GO:0035639purine ribonucleoside triphosphate binding
0.30GO:0043021ribonucleoprotein complex binding
0.30GO:0097110scaffold protein binding
0.30GO:0051219phosphoprotein binding
0.30GO:0003723RNA binding
0.30GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36GO:0005634nucleus
0.30GO:0043234protein complex
0.30GO:0044422organelle part
0.30GO:0016020membrane
0.30GO:0031974membrane-enclosed lumen
0.30GO:0043232intracellular non-membrane-bounded organelle
0.40EC:2.7.11.22 GO:0004693
sp|Q8IWT0|ARCH_HUMAN
Protein archease
Search
ZBTB8OS
0.97Zinc finger and BTB domain containing 8 opposite strand
0.78GO:0006388tRNA splicing, via endonucleolytic cleavage and ligation
0.44GO:0048680positive regulation of axon regeneration
0.39GO:0006955immune response
0.42GO:0046872metal ion binding
0.38GO:0005515protein binding
0.35GO:0003723RNA binding
0.84GO:0072669tRNA-splicing ligase complex
0.47GO:0070062extracellular exosome
0.42GO:0005579membrane attack complex
0.40GO:0005654nucleoplasm
sp|Q8IWT1|SCN4B_HUMAN
Sodium channel subunit beta-4
Search
SCN4B
0.97Sodium voltage-gated channel beta subunit 4
0.65GO:0086016AV node cell action potential
0.64GO:0086012membrane depolarization during cardiac muscle cell action potential
0.64GO:0060307regulation of ventricular cardiac muscle cell membrane repolarization
0.63GO:0010765positive regulation of sodium ion transport
0.63GO:0086002cardiac muscle cell action potential involved in contraction
0.63GO:0086091regulation of heart rate by cardiac conduction
0.62GO:2000649regulation of sodium ion transmembrane transporter activity
0.57GO:0035725sodium ion transmembrane transport
0.66GO:0086006voltage-gated sodium channel activity involved in cardiac muscle cell action potential
0.62GO:0017080sodium channel regulator activity
0.61GO:0044325ion channel binding
0.40GO:0022832voltage-gated channel activity
0.39GO:0022839ion gated channel activity
0.39GO:0008381mechanosensitive ion channel activity
0.63GO:0014704intercalated disc
0.60GO:0001518voltage-gated sodium channel complex
sp|Q8IWT3|CUL9_HUMAN
Cullin-9
Search
CUL9
0.97Cullin-9
0.71GO:0006511ubiquitin-dependent protein catabolic process
0.71GO:0007088regulation of mitotic nuclear division
0.70GO:0000226microtubule cytoskeleton organization
0.68GO:0016567protein ubiquitination
0.44GO:0050775positive regulation of dendrite morphogenesis
0.43GO:0001837epithelial to mesenchymal transition
0.43GO:0001890placenta development
0.43GO:0001570vasculogenesis
0.42GO:0000281mitotic cytokinesis
0.37GO:0043687post-translational protein modification
0.77GO:0031625ubiquitin protein ligase binding
0.52GO:0046872metal ion binding
0.35GO:0000982transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35GO:0000987proximal promoter sequence-specific DNA binding
0.34GO:0032559adenyl ribonucleotide binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.34GO:0046983protein dimerization activity
0.72GO:0031461cullin-RING ubiquitin ligase complex
0.52GO:19903933M complex
0.49GO:0005829cytosol
0.42GO:0048471perinuclear region of cytoplasm
0.41GO:0005813centrosome
0.40GO:0005794Golgi apparatus
0.33GO:0005634nucleus
sp|Q8IWT6|LRC8A_HUMAN
Volume-regulated anion channel subunit LRRC8A
Search
LRRC8A
0.93Leucine-rich repeat-containing protein 8A
0.42GO:0006884cell volume homeostasis
0.41GO:0006970response to osmotic stress
0.39GO:0098656anion transmembrane transport
0.44GO:0005225volume-sensitive anion channel activity
0.40GO:0042802identical protein binding
0.40GO:0009986cell surface
0.40GO:0034702ion channel complex
0.36GO:0005886plasma membrane
sp|Q8IWU2|LMTK2_HUMAN
Serine/threonine-protein kinase LMTK2
Search
LMTK2
0.95Serine/threonine-protein kinase LMTK2
0.63GO:0006468protein phosphorylation
0.45GO:0033572transferrin transport
0.45GO:0001881receptor recycling
0.45GO:0045022early endosome to late endosome transport
0.44GO:0032456endocytic recycling
0.44GO:0018210peptidyl-threonine modification
0.44GO:0032515negative regulation of phosphoprotein phosphatase activity
0.43GO:0018209peptidyl-serine modification
0.36GO:0018212peptidyl-tyrosine modification
0.34GO:0048011neurotrophin TRK receptor signaling pathway
0.64GO:0004672protein kinase activity
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.47GO:0070853myosin VI binding
0.44GO:0004864protein phosphatase inhibitor activity
0.44GO:0055037recycling endosome
0.43GO:0005769early endosome
0.43GO:0048471perinuclear region of cytoplasm
0.41GO:0005794Golgi apparatus
0.41GO:0030426growth cone
0.40GO:0005829cytosol
0.40GO:0043025neuronal cell body
0.30GO:0016020membrane
sp|Q8IWU4|ZNT8_HUMAN
Zinc transporter 8
Search
SLC30A8
0.85Solute carrier family 30 (zinc transporter), member 8
0.81GO:0055069zinc ion homeostasis
0.76GO:0071577zinc II ion transmembrane transport
0.73GO:0072503cellular divalent inorganic cation homeostasis
0.71GO:0030073insulin secretion
0.71GO:0051238sequestering of metal ion
0.69GO:0046916cellular transition metal ion homeostasis
0.68GO:0009749response to glucose
0.66GO:0061088regulation of sequestering of zinc ion
0.57GO:0010043response to zinc ion
0.49GO:0032846positive regulation of homeostatic process
0.76GO:0005385zinc ion transmembrane transporter activity
0.58GO:0042803protein homodimerization activity
0.65GO:0031410cytoplasmic vesicle
0.61GO:0012505endomembrane system
0.49GO:0005886plasma membrane
0.39GO:0043231intracellular membrane-bounded organelle
0.30GO:0016021integral component of membrane
sp|Q8IWU5|SULF2_HUMAN
Extracellular sulfatase Sulf-2
Search
SULF2
0.94Extracellular sulfatase Sulf-2
0.59GO:0014846esophagus smooth muscle contraction
0.59GO:0035860glial cell-derived neurotrophic factor receptor signaling pathway
0.58GO:2000345regulation of hepatocyte proliferation
0.58GO:0035413positive regulation of catenin import into nucleus
0.58GO:0097421liver regeneration
0.58GO:0032836glomerular basement membrane development
0.58GO:0003094glomerular filtration
0.57GO:0040037negative regulation of fibroblast growth factor receptor signaling pathway
0.57GO:0010575positive regulation of vascular endothelial growth factor production
0.57GO:0060384innervation
0.74GO:0008484sulfuric ester hydrolase activity
0.66GO:0005509calcium ion binding
0.33GO:0046983protein dimerization activity
0.72GO:0009986cell surface
0.67GO:0005794Golgi apparatus
0.67GO:0005783endoplasmic reticulum
0.42GO:0005886plasma membrane
0.35GO:0005615extracellular space
0.35GO:0031984organelle subcompartment
0.34GO:0005764lysosome
0.30GO:0031224intrinsic component of membrane
0.74EC:3.1.6 GO:0008484
sp|Q8IWU6|SULF1_HUMAN
Extracellular sulfatase Sulf-1
Search
SULF1
0.94Extracellular 6-O-endosulfatase
0.60GO:0014846esophagus smooth muscle contraction
0.60GO:0035860glial cell-derived neurotrophic factor receptor signaling pathway
0.60GO:0060686negative regulation of prostatic bud formation
0.58GO:0040037negative regulation of fibroblast growth factor receptor signaling pathway
0.58GO:0030336negative regulation of cell migration
0.58GO:0060384innervation
0.58GO:0002063chondrocyte development
0.57GO:0030201heparan sulfate proteoglycan metabolic process
0.57GO:0043009chordate embryonic development
0.56GO:0001937negative regulation of endothelial cell proliferation
0.74GO:0008484sulfuric ester hydrolase activity
0.63GO:0005509calcium ion binding
0.68GO:0009986cell surface
0.64GO:0005794Golgi apparatus
0.63GO:0005783endoplasmic reticulum
0.53GO:0045121membrane raft
0.50GO:0005615extracellular space
0.41GO:0005886plasma membrane
0.37GO:0031984organelle subcompartment
0.30GO:0031224intrinsic component of membrane
0.74EC:3.1.6 GO:0008484
sp|Q8IWU9|TPH2_HUMAN
Tryptophan 5-hydroxylase 2
Search
TPH2
0.97Neuronal tryptophan hydroxylase
0.84GO:0042427serotonin biosynthetic process
0.68GO:0009072aromatic amino acid family metabolic process
0.52GO:0055114oxidation-reduction process
0.39GO:0071285cellular response to lithium ion
0.39GO:0014823response to activity
0.38GO:0046849bone remodeling
0.38GO:0045600positive regulation of fat cell differentiation
0.38GO:0043627response to estrogen
0.38GO:0051384response to glucocorticoid
0.38GO:0051592response to calcium ion
0.84GO:0004510tryptophan 5-monooxygenase activity
0.62GO:0005506iron ion binding
0.51GO:0043005neuron projection
0.34GO:0005829cytosol
0.84EC:1.14.16.4 GO:0004510
sp|Q8IWV1|LAX1_HUMAN
Lymphocyte transmembrane adapter 1
Search
LAX1
0.97Lymphocyte transmembrane adapter 1
0.76GO:0051249regulation of lymphocyte activation
0.74GO:0006955immune response
0.65GO:1903038negative regulation of leukocyte cell-cell adhesion
0.65GO:0000188inactivation of MAPK activity
0.64GO:0042113B cell activation
0.64GO:0002695negative regulation of leukocyte activation
0.51GO:0035556intracellular signal transduction
0.38GO:0048305immunoglobulin secretion
0.37GO:0050851antigen receptor-mediated signaling pathway
0.37GO:0070588calcium ion transmembrane transport
0.67GO:0042169SH2 domain binding
0.61GO:0019901protein kinase binding
0.37GO:0005388calcium-transporting ATPase activity
0.34GO:0032559adenyl ribonucleotide binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.56GO:0005794Golgi apparatus
0.54GO:0005829cytosol
0.46GO:0005886plasma membrane
0.39GO:0045121membrane raft
0.30GO:0016021integral component of membrane
0.37EC:3.6.3.8 GO:0005388
sp|Q8IWV2|CNTN4_HUMAN
Contactin-4
Search
CNTN4
0.92LOW QUALITY PROTEIN: contactin-4
0.77GO:0007411axon guidance
0.71GO:0007155cell adhesion
0.54GO:0045665negative regulation of neuron differentiation
0.40GO:0007420brain development
0.38GO:0006501C-terminal protein lipidation
0.36GO:0007413axonal fasciculation
0.35GO:0048167regulation of synaptic plasticity
0.34GO:0045747positive regulation of Notch signaling pathway
0.47GO:0005112Notch binding
0.41GO:0031225anchored component of membrane
0.37GO:0005576extracellular region
0.36GO:0005886plasma membrane
0.35GO:0030424axon
0.30GO:0016021integral component of membrane
sp|Q8IWV7|UBR1_HUMAN
E3 ubiquitin-protein ligase UBR1
Search
UBR1
0.90Ubiquitin protein ligase E3 component n-recognin 1
0.68GO:0030163protein catabolic process
0.61GO:0071233cellular response to leucine
0.58GO:0032007negative regulation of TOR signaling
0.52GO:0016567protein ubiquitination
0.52GO:0043632modification-dependent macromolecule catabolic process
0.46GO:0006508proteolysis
0.62GO:0070728leucine binding
0.60GO:0008270zinc ion binding
0.53GO:0004842ubiquitin-protein transferase activity
0.53GO:0016874ligase activity
0.43GO:0061659ubiquitin-like protein ligase activity
0.35GO:0005515protein binding
0.54GO:0000151ubiquitin ligase complex
0.52GO:1905369endopeptidase complex
0.45GO:0043234protein complex
0.36GO:0005737cytoplasm
0.30GO:0016020membrane
0.53EC:6 GO:0016874
0.53KEGG:R03876 GO:0004842
sp|Q8IWV8|UBR2_HUMAN
E3 ubiquitin-protein ligase UBR2
Search
UBR2
0.95Ubiquitin protein ligase E3 component n-recognin 2
0.69GO:0030163protein catabolic process
0.60GO:0033522histone H2A ubiquitination
0.60GO:0071233cellular response to leucine
0.57GO:0010529negative regulation of transposition
0.57GO:0007141male meiosis I
0.56GO:0032007negative regulation of TOR signaling
0.56GO:0006342chromatin silencing
0.53GO:0007131reciprocal meiotic recombination
0.53GO:0007283spermatogenesis
0.52GO:0043632modification-dependent macromolecule catabolic process
0.62GO:0008270zinc ion binding
0.60GO:0070728leucine binding
0.54GO:0061630ubiquitin protein ligase activity
0.53GO:0016874ligase activity
0.34GO:0005515protein binding
0.54GO:0000151ubiquitin ligase complex
0.49GO:0000785chromatin
0.37GO:0005737cytoplasm
0.34GO:0005634nucleus
0.53EC:6 GO:0016874
sp|Q8IWW6|RHG12_HUMAN
Rho GTPase-activating protein 12
Search
ARHGAP12
0.95Rho-type GTPase-activating protein 12
0.69GO:0043547positive regulation of GTPase activity
0.60GO:0007165signal transduction
0.58GO:0006911phagocytosis, engulfment
0.57GO:0002011morphogenesis of an epithelial sheet
0.57GO:0051058negative regulation of small GTPase mediated signal transduction
0.52GO:0007015actin filament organization
0.70GO:0005096GTPase activator activity
0.59GO:0001891phagocytic cup
0.34GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q8IWW8|HOT_HUMAN
Hydroxyacid-oxoacid transhydrogenase, mitochondrial
Search
ADHFE1
0.91Hydroxyacid-oxoacid transhydrogenase
0.53GO:0055114oxidation-reduction process
0.34GO:0006006glucose metabolic process
0.33GO:0042254ribosome biogenesis
0.54GO:0016491oxidoreductase activity
0.54GO:0046872metal ion binding
0.33GO:0050661NADP binding
0.33GO:0051287NAD binding
0.37GO:0005829cytosol
0.36GO:0005739mitochondrion
0.32GO:0005634nucleus
0.54EC:1 GO:0016491
sp|Q8IWX5|SGPP2_HUMAN
Sphingosine-1-phosphate phosphatase 2
Search
SGPP2
0.97Sphingosine-1-phosphate phosphatase 2
0.63GO:0006670sphingosine metabolic process
0.51GO:0016311dephosphorylation
0.38GO:0006668sphinganine-1-phosphate metabolic process
0.36GO:0097191extrinsic apoptotic signaling pathway
0.36GO:0097193intrinsic apoptotic signaling pathway
0.36GO:0030148sphingolipid biosynthetic process
0.65GO:0042392sphingosine-1-phosphate phosphatase activity
0.38GO:0070780dihydrosphingosine-1-phosphate phosphatase activity
0.52GO:0005783endoplasmic reticulum
0.36GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.36GO:0031984organelle subcompartment
0.35GO:0005654nucleoplasm
0.30GO:0016021integral component of membrane
sp|Q8IWX7|UN45B_HUMAN
Protein unc-45 homolog B
Search
UNC45B
0.97Unc-45 myosin chaperone B
0.72GO:0061077chaperone-mediated protein folding
0.60GO:0002088lens development in camera-type eye
0.58GO:0007517muscle organ development
0.56GO:0048747muscle fiber development
0.56GO:0030239myofibril assembly
0.55GO:0048738cardiac muscle tissue development
0.36GO:0051216cartilage development
0.36GO:0001525angiogenesis
0.36GO:0008015blood circulation
0.80GO:0051879Hsp90 protein binding
0.45GO:0045296cadherin binding
0.64GO:0005829cytosol
0.56GO:0030018Z disc
0.45GO:0016607nuclear speck
0.42GO:0005794Golgi apparatus
0.38GO:0031672A band
0.37GO:0048471perinuclear region of cytoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q8IWX8|CHERP_HUMAN
Calcium homeostasis endoplasmic reticulum protein
Search
CHERP
0.92calcium homeostasis endoplasmic reticulum protein isoform X2
0.62GO:0051533positive regulation of NFAT protein import into nucleus
0.58GO:0006396RNA processing
0.58GO:0051209release of sequestered calcium ion into cytosol
0.55GO:0008285negative regulation of cell proliferation
0.35GO:0007399nervous system development
0.34GO:0016071mRNA metabolic process
0.58GO:0044325ion channel binding
0.55GO:0003723RNA binding
0.55GO:0048471perinuclear region of cytoplasm
0.40GO:0033017sarcoplasmic reticulum membrane
0.34GO:0005654nucleoplasm
sp|Q8IWY4|SCUB1_HUMAN
Signal peptide, CUB and EGF-like domain-containing protein 1
Search
0.84Signal peptide, CUB domain and EGF like domain containing 1
0.45GO:0045880positive regulation of smoothened signaling pathway
0.44GO:0030154cell differentiation
0.43GO:0051260protein homooligomerization
0.41GO:0007165signal transduction
0.41GO:0060215primitive hemopoiesis
0.40GO:0071773cellular response to BMP stimulus
0.39GO:0061061muscle structure development
0.37GO:0006357regulation of transcription by RNA polymerase II
0.32GO:0014706striated muscle tissue development
0.30GO:0022411cellular component disassembly
0.70GO:0005509calcium ion binding
0.42GO:0046982protein heterodimerization activity
0.42GO:0042802identical protein binding
0.35GO:0008289lipid binding
0.46GO:0009986cell surface
0.45GO:0005615extracellular space
0.43GO:0019897extrinsic component of plasma membrane
0.42GO:0098552side of membrane
0.30GO:0016021integral component of membrane
sp|Q8IWY8|ZSC29_HUMAN
Zinc finger and SCAN domain-containing protein 29
Search
0.65Zinc finger protein 690
0.45GO:0097659nucleic acid-templated transcription
0.44GO:1903506regulation of nucleic acid-templated transcription
0.44GO:2000112regulation of cellular macromolecule biosynthetic process
0.44GO:0010468regulation of gene expression
0.43GO:0010467gene expression
0.42GO:0034645cellular macromolecule biosynthetic process
0.51GO:0003676nucleic acid binding
0.46GO:0003700DNA binding transcription factor activity
0.43GO:0046872metal ion binding
0.46GO:0005634nucleus
sp|Q8IWY9|CDAN1_HUMAN
Codanin-1
Search
CDAN1
0.94Congenital dyserythropoietic anemia, type I
0.79GO:0008156negative regulation of DNA replication
0.76GO:0031497chromatin assembly
0.63GO:0008104protein localization
0.41GO:0006998nuclear envelope organization
0.36GO:0007018microtubule-based movement
0.38GO:0005515protein binding
0.36GO:0003777microtubule motor activity
0.36GO:0008289lipid binding
0.33GO:0032559adenyl ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.67GO:0005829cytosol
0.65GO:0012505endomembrane system
0.60GO:0005634nucleus
0.54GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IWZ3|ANKH1_HUMAN
Ankyrin repeat and KH domain-containing protein 1
Search
0.83LOW QUALITY PROTEIN: ankyrin repeat and KH domain-containing protein 1
0.43GO:0060047heart contraction
0.39GO:0045087innate immune response
0.38GO:1900245positive regulation of MDA-5 signaling pathway
0.38GO:1900246positive regulation of RIG-I signaling pathway
0.37GO:0051151negative regulation of smooth muscle cell differentiation
0.37GO:0001955blood vessel maturation
0.37GO:0045947negative regulation of translational initiation
0.37GO:1900087positive regulation of G1/S transition of mitotic cell cycle
0.37GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.36GO:0042742defense response to bacterium
0.59GO:0003723RNA binding
0.38GO:0008190eukaryotic initiation factor 4E binding
0.36GO:0003682chromatin binding
0.36GO:0031965nuclear membrane
0.35GO:0000785chromatin
0.34GO:0005737cytoplasm
0.30GO:0016021integral component of membrane
sp|Q8IWZ4|TRI48_HUMAN
Tripartite motif-containing protein 48
Search
0.97Tripartite motif-containing protein 48
0.33GO:0046597negative regulation of viral entry into host cell
0.33GO:0032897negative regulation of viral transcription
0.33GO:1902186regulation of viral release from host cell
0.33GO:0051091positive regulation of DNA binding transcription factor activity
0.33GO:0007186G-protein coupled receptor signaling pathway
0.33GO:0045087innate immune response
0.32GO:0016567protein ubiquitination
0.62GO:0008270zinc ion binding
0.35GO:0019901protein kinase binding
0.33GO:0004930G-protein coupled receptor activity
0.32GO:0016874ligase activity
0.31GO:0016740transferase activity
0.45GO:0005622intracellular
0.32GO:0043227membrane-bounded organelle
0.30GO:0016020membrane
0.32EC:6 GO:0016874
sp|Q8IWZ5|TRI42_HUMAN
Tripartite motif-containing protein 42
Search
TRIM42
0.97Tripartite motif-containing protein 42
0.39GO:0035556intracellular signal transduction
0.63GO:0008270zinc ion binding
0.35GO:0005515protein binding
0.45GO:0005622intracellular
sp|Q8IWZ6|BBS7_HUMAN
Bardet-Biedl syndrome 7 protein
Search
BBS7
0.97Bardet-Biedl syndrome 7 protein homolog
0.79GO:1905515non-motile cilium assembly
0.62GO:1903929primary palate development
0.60GO:0048736appendage development
0.59GO:0007507heart development
0.58GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.58GO:0045444fat cell differentiation
0.57GO:0007224smoothened signaling pathway
0.55GO:0001654eye development
0.55GO:0008104protein localization
0.55GO:0007420brain development
0.59GO:0001103RNA polymerase II repressing transcription factor binding
0.33GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.33GO:0005262calcium channel activity
0.79GO:0034464BBSome
0.68GO:0036064ciliary basal body
0.59GO:0005930axoneme
0.58GO:0001750photoreceptor outer segment
0.55GO:0005813centrosome
0.46GO:0005634nucleus
0.37GO:0060170ciliary membrane
0.34GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
0.33EC:1.5.1.5 GO:0004488
0.33KEGG:R01220 GO:0004488
sp|Q8IWZ8|SUGP1_HUMAN
SURP and G-patch domain-containing protein 1
Search
SUGP1
0.93SURP and G-patch domain-containing protein 1
0.63GO:0006396RNA processing
0.30GO:0016071mRNA metabolic process
0.59GO:0003723RNA binding
0.30GO:0005515protein binding
0.44GO:0005654nucleoplasm
0.30GO:0032991macromolecular complex
0.30GO:0031224intrinsic component of membrane
sp|Q8IX01|SUGP2_HUMAN
SURP and G-patch domain-containing protein 2
Search
SUGP2
0.97SURP and G-patch domain-containing protein 2
0.63GO:0006396RNA processing
0.37GO:0016071mRNA metabolic process
0.59GO:0003723RNA binding
0.61GO:0016604nuclear body
sp|Q8IX03|KIBRA_HUMAN
Protein KIBRA
Search
WWC1
0.92WW and C2 domain containing 1
0.85GO:0035331negative regulation of hippo signaling
0.83GO:0046621negative regulation of organ growth
0.75GO:0043410positive regulation of MAPK cascade
0.74GO:0000122negative regulation of transcription by RNA polymerase II
0.74GO:0016477cell migration
0.58GO:0032475otolith formation
0.55GO:0071599otic vesicle development
0.35GO:0005975carbohydrate metabolic process
0.77GO:0032947protein complex scaffold activity
0.75GO:0003713transcription coactivator activity
0.74GO:0019900kinase binding
0.40GO:0030674protein binding, bridging
0.36GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds
0.81GO:0032587ruffle membrane
0.75GO:0048471perinuclear region of cytoplasm
0.65GO:0005829cytosol
0.59GO:0005634nucleus
0.36GO:0043234protein complex
0.36EC:3.2.1 GO:0004553
sp|Q8IX04|UEVLD_HUMAN
Ubiquitin-conjugating enzyme E2 variant 3
Search
UEVLD
0.95Ubiquitin-conjugating enzyme E2 variant 3
0.65GO:0015031protein transport
0.60GO:0005975carbohydrate metabolic process
0.59GO:0006464cellular protein modification process
0.57GO:0019752carboxylic acid metabolic process
0.53GO:0055114oxidation-reduction process
0.66GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.38GO:0070062extracellular exosome
0.66EC:1.1.1 GO:0016616
sp|Q8IX05|CD302_HUMAN
CD302 antigen
Search
sp|Q8IX06|GOR_HUMAN
Putative exonuclease GOR
Search
0.64Exonuclease GOR
0.58GO:0090305nucleic acid phosphodiester bond hydrolysis
0.34GO:2000112regulation of cellular macromolecule biosynthetic process
0.34GO:1903506regulation of nucleic acid-templated transcription
0.34GO:0010468regulation of gene expression
0.62GO:0004527exonuclease activity
0.51GO:0003676nucleic acid binding
0.30GO:0005515protein binding
0.39GO:0005634nucleus
0.35GO:0070013intracellular organelle lumen
0.35GO:0005737cytoplasm
0.34GO:0044446intracellular organelle part
sp|Q8IX07|FOG1_HUMAN
Zinc finger protein ZFPM1
Search
ZFPM1
0.86Zinc finger protein, multitype 1
0.62GO:0060377negative regulation of mast cell differentiation
0.62GO:0060318definitive erythrocyte differentiation
0.61GO:0003195tricuspid valve formation
0.61GO:0003192mitral valve formation
0.60GO:0071733transcriptional activation by promoter-enhancer looping
0.60GO:0045403negative regulation of interleukin-4 biosynthetic process
0.60GO:0060319primitive erythrocyte differentiation
0.59GO:0030219megakaryocyte differentiation
0.58GO:0060413atrial septum morphogenesis
0.58GO:0098751bone cell development
0.57GO:0001102RNA polymerase II activating transcription factor binding
0.55GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
0.42GO:0003714transcription corepressor activity
0.36GO:0046872metal ion binding
0.52GO:0017053transcriptional repressor complex
0.50GO:0005667transcription factor complex
0.45GO:0005634nucleus
0.39GO:0005737cytoplasm
0.30GO:0044422organelle part
0.30GO:0031974membrane-enclosed lumen
sp|Q8IX12|CCAR1_HUMAN
Cell division cycle and apoptosis regulator protein 1
Search
CCAR1
0.92Cell division cycle and apoptosis regulator protein 1
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.56GO:0051301cell division
0.54GO:0030335positive regulation of cell migration
0.53GO:0008284positive regulation of cell proliferation
0.50GO:1902679negative regulation of RNA biosynthetic process
0.37GO:0006915apoptotic process
0.36GO:0007049cell cycle
0.35GO:0043065positive regulation of apoptotic process
0.56GO:0030374ligand-dependent nuclear receptor transcription coactivator activity
0.55GO:0001047core promoter binding
0.55GO:0003714transcription corepressor activity
0.35GO:0005515protein binding
0.34GO:0003723RNA binding
0.39GO:0048471perinuclear region of cytoplasm
0.36GO:0005641nuclear envelope lumen
0.34GO:0005654nucleoplasm
0.30GO:0031224intrinsic component of membrane
sp|Q8IX15|HOMEZ_HUMAN
Homeobox and leucine zipper protein Homez
Search
HOMEZ
0.95Homeobox and leucine zipper protein Homez
0.55GO:2001141regulation of RNA biosynthetic process
0.55GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.47GO:0051253negative regulation of RNA metabolic process
0.47GO:0010558negative regulation of macromolecule biosynthetic process
0.47GO:0031327negative regulation of cellular biosynthetic process
0.36GO:0006351transcription, DNA-templated
0.32GO:0090305nucleic acid phosphodiester bond hydrolysis
0.32GO:0048015phosphatidylinositol-mediated signaling
0.32GO:0034968histone lysine methylation
0.55GO:0003677DNA binding
0.51GO:0003714transcription corepressor activity
0.43GO:0003700DNA binding transcription factor activity
0.36GO:0005515protein binding
0.32GO:0004519endonuclease activity
0.32GO:0018024histone-lysine N-methyltransferase activity
0.32GO:0004012phospholipid-translocating ATPase activity
0.32GO:0046872metal ion binding
0.32GO:0004540ribonuclease activity
0.31GO:0016301kinase activity
0.61GO:0005634nucleus
0.52GO:0005829cytosol
0.52GO:0031974membrane-enclosed lumen
0.47GO:0043232intracellular non-membrane-bounded organelle
0.46GO:0044446intracellular organelle part
0.30GO:0031224intrinsic component of membrane
0.32EC:2.1.1.43 GO:0018024
sp|Q8IX18|DHX40_HUMAN
Probable ATP-dependent RNA helicase DHX40
Search
DHX40
0.95DEAH (Asp-Glu-Ala-His) box polypeptide 40
0.51GO:0000398mRNA splicing, via spliceosome
0.67GO:0004386helicase activity
0.54GO:0030554adenyl nucleotide binding
0.53GO:0097367carbohydrate derivative binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.51GO:0008186RNA-dependent ATPase activity
0.48GO:0003676nucleic acid binding
0.44GO:0140098catalytic activity, acting on RNA
0.51GO:0005681spliceosomal complex
0.39GO:0005737cytoplasm
sp|Q8IX19|MCEM1_HUMAN
Mast cell-expressed membrane protein 1
Search
MCEMP1
0.97Mast cell-expressed membrane protein 1
0.46GO:0043312neutrophil degranulation
0.47GO:0035579specific granule membrane
0.47GO:0070821tertiary granule membrane
0.37GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q8IX21|SLF2_HUMAN
SMC5-SMC6 complex localization factor protein 2
Search
SLF2
0.97SMC5-SMC6 complex localization factor protein 2
0.87GO:1990166protein localization to site of double-strand break
0.87GO:0034184positive regulation of maintenance of mitotic sister chromatid cohesion
0.86GO:2000781positive regulation of double-strand break repair
0.78GO:0031334positive regulation of protein complex assembly
0.64GO:0006974cellular response to DNA damage stimulus
0.40GO:0006259DNA metabolic process
0.77GO:0031625ubiquitin protein ligase binding
0.73GO:0032403protein complex binding
0.83GO:0035861site of double-strand break
0.72GO:0000785chromatin
0.61GO:0005634nucleus
0.45GO:0005615extracellular space
sp|Q8IX29|FBX16_HUMAN
F-box only protein 16
Search
FBXO16
0.97F-box only protein 16
sp|Q8IX30|SCUB3_HUMAN
Signal peptide, CUB and EGF-like domain-containing protein 3
Search
SCUBE3
0.89Signal peptide, CUB domain and EGF like domain containing 3
0.59GO:0045880positive regulation of smoothened signaling pathway
0.56GO:0051291protein heterooligomerization
0.54GO:0051260protein homooligomerization
0.48GO:0030154cell differentiation
0.43GO:0007165signal transduction
0.42GO:0007519skeletal muscle tissue development
0.39GO:0022617extracellular matrix disassembly
0.36GO:0007512adult heart development
0.36GO:0003158endothelium development
0.35GO:0007596blood coagulation
0.70GO:0005509calcium ion binding
0.39GO:0046982protein heterodimerization activity
0.39GO:0042802identical protein binding
0.55GO:0009986cell surface
0.47GO:0005615extracellular space
0.43GO:0005886plasma membrane
0.39GO:0019898extrinsic component of membrane
0.39GO:0098552side of membrane
sp|Q8IX90|SKA3_HUMAN
Spindle and kinetochore-associated protein 3
Search
SKA3
0.97Spindle and kinetochore associated complex subunit 3
0.73GO:0007059chromosome segregation
0.63GO:0031110regulation of microtubule polymerization or depolymerization
0.58GO:0000278mitotic cell cycle
0.40GO:0051301cell division
0.35GO:0005515protein binding
0.35GO:0019706protein-cysteine S-palmitoyltransferase activity
0.82GO:0000940condensed chromosome outer kinetochore
0.62GO:0005876spindle microtubule
0.35GO:0005737cytoplasm
0.30GO:0016020membrane
0.35EC:2.3.1.225 GO:0019706
sp|Q8IX94|CTGE4_HUMAN
cTAGE family member 4
Search
0.83Cutaneous T-cell lymphoma-associated antigen 1
0.30GO:0044425membrane part
sp|Q8IX95|CTGE3_HUMAN
Putative cTAGE family member 3
Search
0.12Putative cTAGE family member 3
0.30GO:0044425membrane part
sp|Q8IXA5|SACA3_HUMAN
Sperm acrosome membrane-associated protein 3
Search
0.96LOW QUALITY PROTEIN: sperm acrosome membrane-associated protein 3
0.82GO:0009566fertilization
0.66GO:0045026plasma membrane fusion
0.64GO:0009988cell-cell recognition
0.62GO:0022412cellular process involved in reproduction in multicellular organism
0.54GO:0050830defense response to Gram-positive bacterium
0.53GO:0050829defense response to Gram-negative bacterium
0.50GO:0016998cell wall macromolecule catabolic process
0.42GO:0042117monocyte activation
0.42GO:0043032positive regulation of macrophage activation
0.41GO:0050766positive regulation of phagocytosis
0.79GO:0003796lysozyme activity
0.38GO:0005515protein binding
0.72GO:0002080acrosomal membrane
0.71GO:0043159acrosomal matrix
0.49GO:0005615extracellular space
0.30GO:0016021integral component of membrane
0.79EC:3.2.1.17 GO:0003796
sp|Q8IXB1|DJC10_HUMAN
DnaJ homolog subfamily C member 10
Search
DNAJC10
0.91DnaJ like protein subfamily C member 10
0.79GO:0034975protein folding in endoplasmic reticulum
0.71GO:0030433ubiquitin-dependent ERAD pathway
0.69GO:0045454cell redox homeostasis
0.65GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.59GO:0032781positive regulation of ATPase activity
0.57GO:0001933negative regulation of protein phosphorylation
0.50GO:0055114oxidation-reduction process
0.36GO:0007018microtubule-based movement
0.66GO:0015036disulfide oxidoreductase activity
0.66GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.65GO:0030544Hsp70 protein binding
0.65GO:0051787misfolded protein binding
0.64GO:0051117ATPase binding
0.59GO:0001671ATPase activator activity
0.59GO:0051087chaperone binding
0.36GO:0003777microtubule motor activity
0.36GO:0008017microtubule binding
0.35GO:0016853isomerase activity
0.72GO:0005788endoplasmic reticulum lumen
0.67GO:0034663endoplasmic reticulum chaperone complex
0.30GO:0031224intrinsic component of membrane
0.66EC:1.8.4 GO:0016671
sp|Q8IXB3|TUSC5_HUMAN
Tumor suppressor candidate 5
Search
TUSC5
0.97Tumor suppressor candidate 5 transcript variant 1
0.70GO:0009607response to biotic stimulus
0.70GO:0044381glucose import in response to insulin stimulus
0.69GO:0099638endosome to plasma membrane protein transport
0.64GO:0045026plasma membrane fusion
0.43GO:0048675axon extension
0.35GO:0005515protein binding
0.59GO:0030659cytoplasmic vesicle membrane
0.46GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IXE1|OR4N5_HUMAN
Olfactory receptor 4N5
Search
0.45Olfactory receptor
0.75GO:0050911detection of chemical stimulus involved in sensory perception of smell
0.70GO:0007186G-protein coupled receptor signaling pathway
0.75GO:0004984olfactory receptor activity
0.71GO:0004930G-protein coupled receptor activity
0.55GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IXF0|NPAS3_HUMAN
Neuronal PAS domain-containing protein 3
Search
NPAS3
0.95Neuronal PAS domain-containing protein 3
0.55GO:1903506regulation of nucleic acid-templated transcription
0.55GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.52GO:0006351transcription, DNA-templated
0.43GO:1902680positive regulation of RNA biosynthetic process
0.41GO:0032502developmental process
0.38GO:0042711maternal behavior
0.37GO:0001964startle response
0.36GO:0007626locomotory behavior
0.62GO:0046983protein dimerization activity
0.43GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.37GO:0003677DNA binding
0.57GO:0005634nucleus
0.50GO:0005829cytosol
0.49GO:0031974membrane-enclosed lumen
0.44GO:0044446intracellular organelle part
sp|Q8IXF9|AQ12A_HUMAN
Aquaporin-12A
Search
0.67Aquaporin
0.54GO:0055085transmembrane transport
0.35GO:0071391cellular response to estrogen stimulus
0.34GO:0042981regulation of apoptotic process
0.34GO:0006468protein phosphorylation
0.67GO:0015267channel activity
0.35GO:0004674protein serine/threonine kinase activity
0.33GO:0030554adenyl nucleotide binding
0.33GO:0032555purine ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.36GO:0005737cytoplasm
0.30GO:0044425membrane part
0.35EC:2.7.11 GO:0004674
sp|Q8IXH6|T53I2_HUMAN
Tumor protein p53-inducible nuclear protein 2
Search
TP53INP2
0.90Tumor protein p53-inducible nuclear protein 2
0.75GO:0010508positive regulation of autophagy
0.70GO:0045893positive regulation of transcription, DNA-templated
0.61GO:0000045autophagosome assembly
0.60GO:0001649osteoblast differentiation
0.59GO:1903828negative regulation of cellular protein localization
0.59GO:0001894tissue homeostasis
0.53GO:0006511ubiquitin-dependent protein catabolic process
0.39GO:0008285negative regulation of cell proliferation
0.38GO:0035076ecdysone receptor-mediated signaling pathway
0.36GO:0006357regulation of transcription by RNA polymerase II
0.58GO:0043130ubiquitin binding
0.38GO:0035258steroid hormone receptor binding
0.38GO:0030374ligand-dependent nuclear receptor transcription coactivator activity
0.33GO:0001106RNA polymerase II transcription corepressor activity
0.33GO:0019212phosphatase inhibitor activity
0.33GO:0003682chromatin binding
0.33GO:0016209antioxidant activity
0.32GO:0016301kinase activity
0.62GO:0005776autophagosome
0.51GO:0005829cytosol
0.48GO:0005634nucleus
0.39GO:0031410cytoplasmic vesicle
0.38GO:0031974membrane-enclosed lumen
0.36GO:0044446intracellular organelle part
0.33GO:0000428DNA-directed RNA polymerase complex
sp|Q8IXH7|NELFD_HUMAN
Negative elongation factor C/D
Search
NELFCD
0.94Negative elongation factor D
0.72GO:0045892negative regulation of transcription, DNA-templated
0.55GO:0006414translational elongation
0.35GO:0006351transcription, DNA-templated
0.34GO:0050434positive regulation of viral transcription
0.56GO:0003746translation elongation factor activity
0.33GO:0005515protein binding
0.33GO:0008270zinc ion binding
0.61GO:0005634nucleus
0.35GO:0031974membrane-enclosed lumen
0.34GO:0043234protein complex
0.34GO:0044446intracellular organelle part
0.30GO:0016020membrane
sp|Q8IXH8|CAD26_HUMAN
Cadherin-like protein 26
Search
CDH26
0.97Cadherin 26, tandem duplicate 1
0.78GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.37GO:0072137condensed mesenchymal cell proliferation
0.37GO:0007166cell surface receptor signaling pathway
0.37GO:0048731system development
0.36GO:0007186G-protein coupled receptor signaling pathway
0.34GO:0007267cell-cell signaling
0.34GO:0022405hair cycle process
0.34GO:0071773cellular response to BMP stimulus
0.34GO:0009913epidermal cell differentiation
0.33GO:0060471cortical granule exocytosis
0.70GO:0005509calcium ion binding
0.37GO:0004930G-protein coupled receptor activity
0.32GO:0004725protein tyrosine phosphatase activity
0.55GO:0005886plasma membrane
0.34GO:0030057desmosome
0.30GO:0016021integral component of membrane
0.32EC:3.1.3.48 GO:0004725
sp|Q8IXI1|MIRO2_HUMAN
Mitochondrial Rho GTPase 2
Search
RHOT2
0.72Mitochondrial Rho GTPase
0.71GO:0007005mitochondrion organization
0.60GO:1905710positive regulation of membrane permeability
0.60GO:0047497mitochondrion transport along microtubule
0.56GO:0097190apoptotic signaling pathway
0.54GO:0006839mitochondrial transport
0.49GO:0019725cellular homeostasis
0.49GO:0061024membrane organization
0.37GO:0034640establishment of mitochondrion localization by microtubule attachment
0.37GO:1902513regulation of organelle transport along microtubule
0.36GO:0046928regulation of neurotransmitter secretion
0.68GO:0005509calcium ion binding
0.66GO:0003924GTPase activity
0.64GO:0032550purine ribonucleoside binding
0.64GO:0019001guanyl nucleotide binding
0.53GO:0032555purine ribonucleotide binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.34GO:0005515protein binding
0.33GO:0003735structural constituent of ribosome
0.78GO:0031307integral component of mitochondrial outer membrane
0.48GO:0005829cytosol
0.37GO:0070062extracellular exosome
0.34GO:0019866organelle inner membrane
0.33GO:0005886plasma membrane
0.33GO:0005840ribosome
sp|Q8IXI2|MIRO1_HUMAN
Mitochondrial Rho GTPase 1
Search
RHOT1
0.70Mitochondrial Rho GTPase
0.73GO:0007005mitochondrion organization
0.53GO:1905710positive regulation of membrane permeability
0.53GO:0047497mitochondrion transport along microtubule
0.50GO:0097190apoptotic signaling pathway
0.49GO:0006839mitochondrial transport
0.45GO:0019725cellular homeostasis
0.45GO:0061024membrane organization
0.40GO:0034640establishment of mitochondrion localization by microtubule attachment
0.39GO:1902513regulation of organelle transport along microtubule
0.38GO:0046928regulation of neurotransmitter secretion
0.69GO:0005509calcium ion binding
0.67GO:0003924GTPase activity
0.65GO:0032550purine ribonucleoside binding
0.65GO:0019001guanyl nucleotide binding
0.53GO:0032555purine ribonucleotide binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.34GO:0005515protein binding
0.33GO:0003735structural constituent of ribosome
0.80GO:0031307integral component of mitochondrial outer membrane
0.33GO:0005829cytosol
0.33GO:0005840ribosome
0.32GO:0005886plasma membrane
sp|Q8IXJ6|SIR2_HUMAN
NAD-dependent protein deacetylase sirtuin-2
Search
SIRT2
0.60NAD-dependent protein deacetylase
0.77GO:0016575histone deacetylation
0.59GO:2000777positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
0.58GO:0061433cellular response to caloric restriction
0.58GO:0061428negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.58GO:0090042tubulin deacetylation
0.57GO:1900195positive regulation of oocyte maturation
0.57GO:0034983peptidyl-lysine deacetylation
0.57GO:0071872cellular response to epinephrine stimulus
0.57GO:0048012hepatocyte growth factor receptor signaling pathway
0.57GO:1900425negative regulation of defense response to bacterium
0.79GO:0017136NAD-dependent histone deacetylase activity
0.77GO:0070403NAD+ binding
0.61GO:0008270zinc ion binding
0.58GO:0042903tubulin deacetylase activity
0.57GO:0034739histone deacetylase activity (H4-K16 specific)
0.55GO:0035035histone acetyltransferase binding
0.53GO:0042826histone deacetylase binding
0.52GO:0043130ubiquitin binding
0.51GO:0003682chromatin binding
0.48GO:0008134transcription factor binding
0.57GO:0033010paranodal junction
0.56GO:0043220Schmidt-Lanterman incisure
0.55GO:0072687meiotic spindle
0.54GO:0043204perikaryon
0.53GO:0030496midbody
0.53GO:0005814centriole
0.52GO:0072686mitotic spindle
0.51GO:0048471perinuclear region of cytoplasm
0.51GO:0005813centrosome
0.49GO:0005730nucleolus
0.35EC:2.4.2.30 GO:0003950
sp|Q8IXJ9|ASXL1_HUMAN
Putative Polycomb group protein ASXL1
Search
ASXL1
0.95Additional sex combs like 1, transcriptional regulator
0.72GO:0035359negative regulation of peroxisome proliferator activated receptor signaling pathway
0.72GO:0048386positive regulation of retinoic acid receptor signaling pathway
0.71GO:0048539bone marrow development
0.71GO:0060430lung saccule development
0.69GO:0035521monoubiquitinated histone deubiquitination
0.68GO:0045599negative regulation of fat cell differentiation
0.67GO:0048538thymus development
0.67GO:0032526response to retinoic acid
0.64GO:0003007heart morphogenesis
0.63GO:0030097hemopoiesis
0.71GO:0042975peroxisome proliferator activated receptor binding
0.69GO:0042974retinoic acid receptor binding
0.62GO:0003713transcription coactivator activity
0.55GO:0003677DNA binding
0.71GO:0035517PR-DUB complex
sp|Q8IXK0|PHC2_HUMAN
Polyhomeotic-like protein 2
Search
PHC2
0.94Polyhomeotic homolog 2
0.69GO:0007283spermatogenesis
0.66GO:0042802identical protein binding
0.63GO:0008270zinc ion binding
0.77GO:0035102PRC1 complex
0.71GO:0000792heterochromatin
0.63GO:0005654nucleoplasm
sp|Q8IXK2|GLT12_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 12
Search
GALNT12
0.64Polypeptide N-acetylgalactosaminyltransferase
0.72GO:0006486protein glycosylation
0.33GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.32GO:0005975carbohydrate metabolic process
0.68GO:0030246carbohydrate binding
0.63GO:0016757transferase activity, transferring glycosyl groups
0.35GO:0140096catalytic activity, acting on a protein
0.34GO:0046872metal ion binding
0.72GO:0000139Golgi membrane
0.37GO:0048471perinuclear region of cytoplasm
0.36GO:0070062extracellular exosome
0.32GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
0.63EC:2.4 GO:0016757
sp|Q8IXL6|FA20C_HUMAN
Extracellular serine/threonine protein kinase FAM20C
Search
FAM20C
0.88Dentin matrix protein 4
0.56GO:0036179osteoclast maturation
0.56GO:0006468protein phosphorylation
0.56GO:0031214biomineral tissue development
0.55GO:0071895odontoblast differentiation
0.53GO:0097187dentinogenesis
0.53GO:0040036regulation of fibroblast growth factor receptor signaling pathway
0.52GO:0030501positive regulation of bone mineralization
0.52GO:0045669positive regulation of osteoblast differentiation
0.52GO:0097186amelogenesis
0.46GO:0051174regulation of phosphorus metabolic process
0.61GO:0004674protein serine/threonine kinase activity
0.49GO:0030145manganese ion binding
0.46GO:0005509calcium ion binding
0.34GO:0043565sequence-specific DNA binding
0.34GO:0003700DNA binding transcription factor activity
0.34GO:0032559adenyl ribonucleotide binding
0.34GO:0005515protein binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.50GO:0005615extracellular space
0.49GO:0005794Golgi apparatus
0.37GO:1903561extracellular vesicle
0.36GO:0005788endoplasmic reticulum lumen
0.35GO:0005634nucleus
0.34GO:0031301integral component of organelle membrane
0.33GO:0098796membrane protein complex
0.33GO:0019866organelle inner membrane
0.61EC:2.7.11 GO:0004674
sp|Q8IXL7|MSRB3_HUMAN
Methionine-R-sulfoxide reductase B3
Search
MSRB3
0.97Methionine sulfoxide reductase B3 transcript variant 1
0.73GO:0030091protein repair
0.67GO:0006979response to oxidative stress
0.51GO:0055114oxidation-reduction process
0.45GO:0048839inner ear development
0.74GO:0033743peptide-methionine (R)-S-oxide reductase activity
0.48GO:0008270zinc ion binding
0.39GO:0033745L-methionine-(R)-S-oxide reductase activity
0.34GO:0005515protein binding
0.51GO:0005783endoplasmic reticulum
0.46GO:0005739mitochondrion
0.35GO:0005829cytosol
0.34GO:0009570chloroplast stroma
0.30GO:0031224intrinsic component of membrane
0.74EC:1.8.4 EC:1.8.4.12 GO:0033743
0.74KEGG:R07607 GO:0033743
sp|Q8IXL9|IQCF2_HUMAN
IQ domain-containing protein F2
Search
0.97IQ domain-containing protein F2
0.62GO:2000344positive regulation of acrosome reaction
0.61GO:0060474positive regulation of flagellated sperm motility involved in capacitation
0.35GO:0043043peptide biosynthetic process
0.35GO:0044267cellular protein metabolic process
0.34GO:0010467gene expression
0.34GO:0060216definitive hemopoiesis
0.34GO:0009059macromolecule biosynthetic process
0.75GO:0005516calmodulin binding
0.36GO:0003735structural constituent of ribosome
0.34GO:0003676nucleic acid binding
0.64GO:0001669acrosomal vesicle
0.36GO:0005840ribosome
0.34GO:0031514motile cilium
0.30GO:0016020membrane
sp|Q8IXM2|BAP18_HUMAN
Chromatin complexes subunit BAP18
Search
0.94Chromatin complexes subunit BAP18
0.37GO:0016569covalent chromatin modification
0.53GO:0003677DNA binding
0.33GO:0005515protein binding
0.84GO:0016589NURF complex
0.82GO:0071339MLL1 complex
0.39GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q8IXM3|RM41_HUMAN
39S ribosomal protein L41, mitochondrial
Search
MRPL41
0.96Mitochondrial ribosomal protein L41
0.49GO:0043043peptide biosynthetic process
0.46GO:0044267cellular protein metabolic process
0.45GO:0010467gene expression
0.44GO:0009059macromolecule biosynthetic process
0.43GO:0006915apoptotic process
0.40GO:0007049cell cycle
0.36GO:0043624cellular protein complex disassembly
0.33GO:0006633fatty acid biosynthetic process
0.32GO:0036211protein modification process
0.32GO:0016310phosphorylation
0.51GO:0003735structural constituent of ribosome
0.35GO:0003723RNA binding
0.35GO:0005515protein binding
0.33GO:0004674protein serine/threonine kinase activity
0.33GO:0016747transferase activity, transferring acyl groups other than amino-acyl groups
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.63GO:0005762mitochondrial large ribosomal subunit
0.35GO:0031966mitochondrial membrane
0.35GO:0019866organelle inner membrane
0.30GO:0031224intrinsic component of membrane
0.33EC:2.7.11 GO:0004674
sp|Q8IXM6|NRM_HUMAN
Nurim
Search
NRM
0.97Nurim (nuclear envelope membrane protein)
0.37GO:0005515protein binding
0.68GO:0031965nuclear membrane
0.43GO:0019866organelle inner membrane
0.39GO:0005652nuclear lamina
0.30GO:0044425membrane part
sp|Q8IXM7|OD3L1_HUMAN
Outer dense fiber protein 3-like protein 1
Search
ODF3L1
0.96Outer dense fiber of sperm tails 3 like 1
0.56GO:0005881cytoplasmic microtubule
0.30GO:0031224intrinsic component of membrane
sp|Q8IXN7|RIMKA_HUMAN
N-acetylaspartylglutamate synthase A
Search
RIMKLA
0.97N-acetylaspartyl-glutamate synthetase A
0.60GO:0006464cellular protein modification process
0.34GO:0008652cellular amino acid biosynthetic process
0.69GO:0072590N-acetyl-L-aspartate-L-glutamate ligase activity
0.55GO:0030554adenyl nucleotide binding
0.54GO:0072591citrate-L-glutamate ligase activity
0.54GO:0097367carbohydrate derivative binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.54GO:0046872metal ion binding
0.41GO:0005737cytoplasm
sp|Q8IXP5|CK053_HUMAN
Uncharacterized protein C11orf53
Search
sp|Q8IXQ3|CI040_HUMAN
Uncharacterized protein C9orf40
Search
sp|Q8IXQ4|GPAM1_HUMAN
GPALPP motifs-containing protein 1
Search
GPALPP1
0.95GPALPP motifs-containing protein 1
0.51GO:0006367transcription initiation from RNA polymerase II promoter
0.44GO:0032049cardiolipin biosynthetic process
0.41GO:0045859regulation of protein kinase activity
0.44GO:0004605phosphatidate cytidylyltransferase activity
0.43GO:0016538cyclin-dependent protein serine/threonine kinase regulator activity
0.53GO:0005674transcription factor TFIIF complex
0.41GO:0016592mediator complex
0.30GO:0016020membrane
0.44EC:2.7.7.41 GO:0004605
sp|Q8IXQ5|KLHL7_HUMAN
Kelch-like protein 7
Search
KLHL7
0.96Kelch like family member 7
0.73GO:0016567protein ubiquitination
0.32GO:0006412translation
0.51GO:0042803protein homodimerization activity
0.44GO:0004842ubiquitin-protein transferase activity
0.32GO:0046872metal ion binding
0.32GO:0003735structural constituent of ribosome
0.83GO:0031463Cul3-RING ubiquitin ligase complex
0.53GO:0048471perinuclear region of cytoplasm
0.50GO:0005730nucleolus
0.48GO:0005654nucleoplasm
0.48GO:0005829cytosol
0.42GO:0005886plasma membrane
0.32GO:0005840ribosome
0.44KEGG:R03876 GO:0004842
sp|Q8IXQ6|PARP9_HUMAN
Poly [ADP-ribose] polymerase 9
Search
PARP9
0.54Poly [ADP-ribose] polymerase
0.62GO:0060332positive regulation of response to interferon-gamma
0.61GO:0035563positive regulation of chromatin binding
0.60GO:2001034positive regulation of double-strand break repair via nonhomologous end joining
0.60GO:0060334regulation of interferon-gamma-mediated signaling pathway
0.60GO:0001961positive regulation of cytokine-mediated signaling pathway
0.59GO:0002230positive regulation of defense response to virus by host
0.59GO:0042531positive regulation of tyrosine phosphorylation of STAT protein
0.57GO:0006471protein ADP-ribosylation
0.57GO:1900182positive regulation of protein localization to nucleus
0.54GO:0000122negative regulation of transcription by RNA polymerase II
0.81GO:0003950NAD+ ADP-ribosyltransferase activity
0.63GO:0072570ADP-D-ribose binding
0.62GO:0097677STAT family protein binding
0.58GO:0001191transcriptional repressor activity, RNA polymerase II transcription factor binding
0.55GO:0042393histone binding
0.55GO:0044389ubiquitin-like protein ligase binding
0.52GO:0004857enzyme inhibitor activity
0.37GO:0070403NAD+ binding
0.36GO:0061608nuclear import signal receptor activity
0.34GO:0008565protein transporter activity
0.57GO:0090734site of DNA damage
0.50GO:0005654nucleoplasm
0.50GO:0005829cytosol
0.46GO:0005739mitochondrion
0.45GO:0043234protein complex
0.30GO:0016020membrane
0.81EC:2.4.2.30 GO:0003950
sp|Q8IXQ8|PDZD9_HUMAN
PDZ domain-containing protein 9
Search
PDZD9
0.97PDZ domain-containing protein 9
sp|Q8IXQ9|ETKMT_HUMAN
Electron transfer flavoprotein beta subunit lysine methyltransferase
Search
ETFBKMT
0.97Electron transfer flavoprotein beta subunit lysine methyltransferase
0.67GO:1904733negative regulation of electron transfer activity
0.67GO:1904736negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.62GO:0018023peptidyl-lysine trimethylation
0.33GO:0006414translational elongation
0.61GO:0008168methyltransferase activity
0.56GO:0031072heat shock protein binding
0.46GO:0140096catalytic activity, acting on a protein
0.32GO:0003735structural constituent of ribosome
0.55GO:0005759mitochondrial matrix
0.46GO:0043234protein complex
0.35GO:0005840ribosome
0.61EC:2.1.1 GO:0008168
sp|Q8IXR5|F178B_HUMAN
Protein FAM178B
Search
0.52GO:0008270zinc ion binding
0.38GO:0019901protein kinase binding
0.40GO:0005622intracellular
0.30GO:0044425membrane part
sp|Q8IXR9|CL056_HUMAN
Uncharacterized protein C12orf56
Search
0.42GO:0016884carbon-nitrogen ligase activity, with glutamine as amido-N-donor
0.42EC:6.3.5 GO:0016884
sp|Q8IXS0|F217A_HUMAN
Protein FAM217A
Search
sp|Q8IXS2|CCD65_HUMAN
Coiled-coil domain-containing protein 65
Search
CCDC65
0.91Coiled-coil domain-containing protein 65
0.86GO:0003352regulation of cilium movement
0.76GO:0060271cilium assembly
0.34GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
0.32GO:0006508proteolysis
0.35GO:0003723RNA binding
0.34GO:0004521endoribonuclease activity
0.33GO:0004843thiol-dependent ubiquitin-specific protease activity
0.36GO:0031514motile cilium
0.30GO:0031224intrinsic component of membrane
sp|Q8IXS6|PALM2_HUMAN
Paralemmin-2
Search
PALM2
0.95Paralemmin
0.69GO:0008360regulation of cell shape
0.42GO:0071257cellular response to electrical stimulus
0.42GO:0060074synapse maturation
0.42GO:0007194negative regulation of adenylate cyclase activity
0.42GO:0051491positive regulation of filopodium assembly
0.42GO:0060160negative regulation of dopamine receptor signaling pathway
0.41GO:0072659protein localization to plasma membrane
0.41GO:0007193adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.38GO:0007010cytoskeleton organization
0.37GO:0016310phosphorylation
0.43GO:0031750D3 dopamine receptor binding
0.38GO:0016301kinase activity
0.42GO:0031527filopodium membrane
0.41GO:0014069postsynaptic density
0.41GO:0044309neuron spine
0.36GO:0016327apicolateral plasma membrane
0.36GO:0097060synaptic membrane
0.36GO:0005634nucleus
0.36GO:0016323basolateral plasma membrane
0.36GO:0030425dendrite
0.36GO:0030424axon
0.35GO:0044306neuron projection terminus
sp|Q8IXS8|F126B_HUMAN
Protein FAM126B
Search
0.79Putative beta-catenin-tcf/lef signaling pathway component drctnnb1a
0.40GO:0072659protein localization to plasma membrane
0.38GO:0046854phosphatidylinositol phosphorylation
0.37GO:0042552myelination
0.36GO:0006260DNA replication
0.36GO:0005515protein binding
0.45GO:0005622intracellular
0.40GO:0005886plasma membrane
0.35GO:0043234protein complex
0.34GO:0043228non-membrane-bounded organelle
0.34GO:0044422organelle part
0.34GO:0043227membrane-bounded organelle
sp|Q8IXT1|DDIAS_HUMAN
DNA damage-induced apoptosis suppressor protein
Search
DDIAS
0.97DNA damage induced apoptosis suppressor
0.87GO:0097752regulation of DNA stability
0.85GO:1902230negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.49GO:0007050cell cycle arrest
0.46GO:0006915apoptotic process
0.44GO:2000270negative regulation of fibroblast apoptotic process
0.44GO:0071447cellular response to hydroperoxide
0.43GO:0071480cellular response to gamma radiation
0.42GO:0034644cellular response to UV
0.42GO:0007286spermatid development
0.41GO:0030097hemopoiesis
0.36GO:0003735structural constituent of ribosome
0.41GO:0005634nucleus
0.38GO:0005737cytoplasm
0.36GO:0030529intracellular ribonucleoprotein complex
0.36GO:0043232intracellular non-membrane-bounded organelle
0.30GO:0016020membrane
sp|Q8IXT2|DMRTD_HUMAN
Doublesex- and mab-3-related transcription factor C2
Search
DMRTC2
0.97Doublesex- and mab-3-related transcription factor C2
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.47GO:0007290spermatid nucleus elongation
0.47GO:1900114positive regulation of histone H3-K9 trimethylation
0.47GO:1900111positive regulation of histone H3-K9 dimethylation
0.46GO:0007141male meiosis I
0.43GO:0007548sex differentiation
0.43GO:2000287positive regulation of myotome development
0.42GO:0014807regulation of somitogenesis
0.64GO:0043565sequence-specific DNA binding
0.61GO:0003700DNA binding transcription factor activity
0.53GO:0046872metal ion binding
0.47GO:0042803protein homodimerization activity
0.40GO:0001012RNA polymerase II regulatory region DNA binding
0.39GO:0003690double-stranded DNA binding
0.35GO:0003735structural constituent of ribosome
0.32GO:0043015gamma-tubulin binding
0.32GO:0005544calcium-dependent phospholipid binding
0.32GO:0008081phosphoric diester hydrolase activity
0.61GO:0005634nucleus
0.46GO:0001741XY body
0.34GO:0005840ribosome
0.33GO:0044430cytoskeletal part
0.32GO:0045111intermediate filament cytoskeleton
0.32GO:0099512supramolecular fiber
0.32GO:0015630microtubule cytoskeleton
0.30GO:0016021integral component of membrane
0.32EC:3.1.4 GO:0008081
sp|Q8IXT5|RB12B_HUMAN
RNA-binding protein 12B
Search
RBM12B
0.92RNA binding motif protein 12B
0.31GO:0030001metal ion transport
0.59GO:0003723RNA binding
0.36GO:0005515protein binding
0.31GO:0046872metal ion binding
0.36GO:0005654nucleoplasm
0.32GO:0031965nuclear membrane
0.32GO:0019013viral nucleocapsid
0.32GO:0030529intracellular ribonucleoprotein complex
0.30GO:0044425membrane part
sp|Q8IXU6|S35F2_HUMAN
Solute carrier family 35 member F2
Search
SLC35F2
0.97Info solute carrier family 35, member F2, like
0.54GO:0055085transmembrane transport
0.56GO:0022857transmembrane transporter activity
0.30GO:0044425membrane part
sp|Q8IXV7|KLD8B_HUMAN
Kelch domain-containing protein 8B
Search
KLHDC8B
0.97LOW QUALITY PROTEIN: kelch domain-containing protein 8B
0.60GO:0016567protein ubiquitination
0.43GO:0051301cell division
0.43GO:0007049cell cycle
0.60GO:0004842ubiquitin-protein transferase activity
0.67GO:0031463Cul3-RING ubiquitin ligase complex
0.62GO:0005829cytosol
0.49GO:0030496midbody
0.30GO:0031224intrinsic component of membrane
0.60KEGG:R03876 GO:0004842
sp|Q8IXW0|LMTD2_HUMAN
Lamin tail domain-containing protein 2
Search
LMNTD2
0.97Lamin tail domain-containing protein 2
0.86GO:0048026positive regulation of mRNA splicing, via spliceosome
sp|Q8IXW5|RPAP2_HUMAN
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Search
RPAP2
0.51Ubiquitin carboxyl-terminal hydrolase
0.85GO:0070940dephosphorylation of RNA polymerase II C-terminal domain
0.83GO:0009301snRNA transcription
0.39GO:0006366transcription by RNA polymerase II
0.37GO:0006511ubiquitin-dependent protein catabolic process
0.33GO:0006569tryptophan catabolic process
0.33GO:0009435NAD biosynthetic process
0.85GO:0008420CTD phosphatase activity
0.40GO:0046872metal ion binding
0.38GO:0004843thiol-dependent ubiquitin-specific protease activity
0.37GO:0005515protein binding
0.34GO:0030429kynureninase activity
0.33GO:0030170pyridoxal phosphate binding
0.32GO:0003676nucleic acid binding
0.71GO:0016591DNA-directed RNA polymerase II, holoenzyme
0.68GO:0005730nucleolus
0.64GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
0.34EC:3.7.1.3 GO:0030429
sp|Q8IXX5|T183A_HUMAN
Transmembrane protein 183A
Search
TMEM183A
0.93Transmembrane domain-containing protein (Fragment)
0.33GO:0005515protein binding
0.30GO:0044425membrane part
sp|Q8IXY8|PPIL6_HUMAN
Peptidyl-prolyl cis-trans isomerase-like 6
Search
PPIL6
0.39Peptidyl-prolyl cis-trans isomerase
0.72GO:0000413protein peptidyl-prolyl isomerization
0.47GO:0006457protein folding
0.32GO:0006367transcription initiation from RNA polymerase II promoter
0.32GO:0034605cellular response to heat
0.32GO:0043043peptide biosynthetic process
0.32GO:0007018microtubule-based movement
0.72GO:0003755peptidyl-prolyl cis-trans isomerase activity
0.34GO:0016018cyclosporin A binding
0.32GO:0003735structural constituent of ribosome
0.32GO:0005515protein binding
0.32GO:0003777microtubule motor activity
0.31GO:0032559adenyl ribonucleotide binding
0.31GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0005802trans-Golgi network
0.33GO:0005829cytosol
0.33GO:0005768endosome
0.32GO:0005672transcription factor TFIIA complex
0.32GO:0005840ribosome
0.30GO:0016020membrane
0.72EC:5.2.1.8 GO:0003755
sp|Q8IXZ2|ZC3H3_HUMAN
Zinc finger CCCH domain-containing protein 3
Search
ZC3H3
0.88Zinc finger CCCH domain-containing protein 3
0.66GO:0010793regulation of mRNA export from nucleus
0.64GO:0032927positive regulation of activin receptor signaling pathway
0.63GO:0016973poly(A)+ mRNA export from nucleus
0.61GO:0006378mRNA polyadenylation
0.46GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
0.32GO:0006351transcription, DNA-templated
0.32GO:2001141regulation of RNA biosynthetic process
0.32GO:2000112regulation of cellular macromolecule biosynthetic process
0.63GO:0070412R-SMAD binding
0.54GO:0046872metal ion binding
0.46GO:0004521endoribonuclease activity
0.41GO:0003723RNA binding
0.36GO:0003677DNA binding
0.32GO:0003700DNA binding transcription factor activity
0.60GO:0005847mRNA cleavage and polyadenylation specificity factor complex
sp|Q8IXZ3|SP8_HUMAN
Transcription factor Sp8
Search
0.96Specificity protein 8
0.55GO:0030326embryonic limb morphogenesis
0.50GO:0009954proximal/distal pattern formation
0.48GO:0009953dorsal/ventral pattern formation
0.45GO:0006357regulation of transcription by RNA polymerase II
0.44GO:0035118embryonic pectoral fin morphogenesis
0.44GO:0045743positive regulation of fibroblast growth factor receptor signaling pathway
0.38GO:0007480imaginal disc-derived leg morphogenesis
0.37GO:0006351transcription, DNA-templated
0.51GO:0003676nucleic acid binding
0.46GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36GO:0046872metal ion binding
0.42GO:0005634nucleus
0.30GO:0016020membrane
sp|Q8IY17|PLPL6_HUMAN
Neuropathy target esterase
Search
PNPLA6
0.93LOW QUALITY PROTEIN: neuropathy target esterase
0.81GO:0046470phosphatidylcholine metabolic process
0.71GO:0016042lipid catabolic process
0.44GO:0032502developmental process
0.40GO:0030514negative regulation of BMP signaling pathway
0.40GO:0032501multicellular organismal process
0.39GO:0120036plasma membrane bounded cell projection organization
0.34GO:0046434organophosphate catabolic process
0.33GO:0044248cellular catabolic process
0.81GO:0004622lysophospholipase activity
0.35GO:0030507spectrin binding
0.34GO:0005516calmodulin binding
0.34GO:0008017microtubule binding
0.43GO:0005783endoplasmic reticulum
0.37GO:0042175nuclear outer membrane-endoplasmic reticulum membrane network
0.36GO:0031984organelle subcompartment
0.34GO:0005874microtubule
0.30GO:0016021integral component of membrane
0.81EC:3.1.1.5 GO:0004622
sp|Q8IY18|SMC5_HUMAN
Structural maintenance of chromosomes protein 5
Search
0.78GO:0007062sister chromatid cohesion
0.77GO:0000724double-strand break repair via homologous recombination
0.65GO:0034184positive regulation of maintenance of mitotic sister chromatid cohesion
0.62GO:0090398cellular senescence
0.61GO:0000722telomere maintenance via recombination
0.38GO:0006303double-strand break repair via nonhomologous end joining
0.37GO:0051301cell division
0.32GO:0043043peptide biosynthetic process
0.31GO:0044267cellular protein metabolic process
0.31GO:0010467gene expression
0.35GO:0032559adenyl ribonucleotide binding
0.35GO:0008144drug binding
0.35GO:0035639purine ribonucleoside triphosphate binding
0.34GO:0005515protein binding
0.32GO:0003735structural constituent of ribosome
0.81GO:0030915Smc5-Smc6 complex
0.64GO:0035061interchromatin granule
0.61GO:0016605PML body
0.59GO:0035861site of double-strand break
0.58GO:0000781chromosome, telomeric region
0.57GO:0016607nuclear speck
0.54GO:0030054cell junction
0.41GO:0000803sex chromosome
0.36GO:0055044symplast
0.32GO:0005840ribosome
sp|Q8IY21|DDX60_HUMAN
Probable ATP-dependent RNA helicase DDX60
Search
DDX60
0.96DEAD-box helicase 60 like
0.73GO:1900245positive regulation of MDA-5 signaling pathway
0.72GO:1900246positive regulation of RIG-I signaling pathway
0.63GO:0009615response to virus
0.62GO:0002252immune effector process
0.61GO:0098542defense response to other organism
0.64GO:0003727single-stranded RNA binding
0.61GO:0003725double-stranded RNA binding
0.58GO:0003690double-stranded DNA binding
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.43GO:0004386helicase activity
0.63GO:0045111intermediate filament cytoskeleton
0.56GO:0005829cytosol
sp|Q8IY22|CMIP_HUMAN
C-Maf-inducing protein
Search
CMIP
0.97C-Maf-inducing protein isoform C-Mip
0.37GO:0005515protein binding
0.69GO:0005654nucleoplasm
0.68GO:0005829cytosol
0.30GO:0031224intrinsic component of membrane
sp|Q8IY26|PLPP6_HUMAN
Phospholipid phosphatase 6
Search
PLPP6
0.93Phospholipid phosphatase 6
0.68GO:0046839phospholipid dephosphorylation
0.47GO:0010832negative regulation of myotube differentiation
0.40GO:0006695cholesterol biosynthetic process
0.74GO:0042577lipid phosphatase activity
0.43GO:0005635nuclear envelope
0.35GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IY31|IFT20_HUMAN
Intraflagellar transport protein 20 homolog
Search
IFT20
0.96Intraflagellar transport protein 20
0.59GO:0036372opsin transport
0.58GO:0051642centrosome localization
0.58GO:0061512protein localization to cilium
0.57GO:0035845photoreceptor cell outer segment organization
0.56GO:0042073intraciliary transport
0.56GO:0090102cochlea development
0.56GO:0034067protein localization to Golgi apparatus
0.56GO:0060122inner ear receptor cell stereocilium organization
0.56GO:0008542visual learning
0.56GO:2000785regulation of autophagosome assembly
0.59GO:0002046opsin binding
0.54GO:0017137Rab GTPase binding
0.77GO:0031514motile cilium
0.59GO:1902636kinociliary basal body
0.57GO:0044292dendrite terminus
0.57GO:0030992intraciliary transport particle B
0.56GO:0097546ciliary base
0.56GO:0005814centriole
0.56GO:0032391photoreceptor connecting cilium
0.55GO:0032420stereocilium
0.55GO:0005902microvillus
0.55GO:0001750photoreceptor outer segment
sp|Q8IY33|MILK2_HUMAN
MICAL-like protein 2
Search
MICALL2
0.83MICAL like 2
0.84GO:0032456endocytic recycling
0.64GO:1903955positive regulation of protein targeting to mitochondrion
0.61GO:0070830bicellular tight junction assembly
0.61GO:0034446substrate adhesion-dependent cell spreading
0.59GO:0030041actin filament polymerization
0.57GO:0031175neuron projection development
0.55GO:0031532actin cytoskeleton reorganization
0.39GO:1990126retrograde transport, endosome to plasma membrane
0.39GO:0036010protein localization to endosome
0.39GO:0097320plasma membrane tubulation
0.81GO:0017137Rab GTPase binding
0.66GO:0031005filamin binding
0.59GO:0042805actinin binding
0.56GO:0051015actin filament binding
0.52GO:0046872metal ion binding
0.39GO:0070300phosphatidic acid binding
0.38GO:0045296cadherin binding
0.37GO:0042802identical protein binding
0.33GO:0043565sequence-specific DNA binding
0.33GO:0003743translation initiation factor activity
0.60GO:0097517contractile actin filament bundle
0.60GO:0042641actomyosin
0.60GO:0055037recycling endosome
0.58GO:0005923bicellular tight junction
0.44GO:0005886plasma membrane
0.42GO:0043005neuron projection
0.39GO:0005829cytosol
0.38GO:0005770late endosome
0.37GO:0010008endosome membrane
0.37GO:0019898extrinsic component of membrane
sp|Q8IY34|S15A3_HUMAN
Solute carrier family 15 member 3
Search
SLC15A3
0.96Solute carrier family 15 (oligopeptide transporter), member 4
0.66GO:0006857oligopeptide transport
0.54GO:0055085transmembrane transport
0.39GO:0015031protein transport
0.35GO:0006812cation transport
0.35GO:0043312neutrophil degranulation
0.34GO:0015802basic amino acid transport
0.34GO:0030163protein catabolic process
0.34GO:0045117azole transport
0.34GO:0015807L-amino acid transport
0.33GO:0015893drug transport
0.56GO:0022857transmembrane transporter activity
0.37GO:0015197peptide transporter activity
0.35GO:0005515protein binding
0.43GO:0043231intracellular membrane-bounded organelle
0.38GO:0098805whole membrane
0.38GO:0098588bounding membrane of organelle
0.36GO:0044446intracellular organelle part
0.35GO:0044444cytoplasmic part
0.34GO:0012506vesicle membrane
0.34GO:0097708intracellular vesicle
0.33GO:0012505endomembrane system
0.32GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IY37|DHX37_HUMAN
Probable ATP-dependent RNA helicase DHX37
Search
DHX37
0.97DEAH (Asp-Glu-Ala-His) box polypeptide 37
0.46GO:0048026positive regulation of mRNA splicing, via spliceosome
0.42GO:0006396RNA processing
0.34GO:0016072rRNA metabolic process
0.34GO:0042254ribosome biogenesis
0.67GO:0004386helicase activity
0.54GO:0032559adenyl ribonucleotide binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.50GO:0003676nucleic acid binding
0.47GO:0008186RNA-dependent ATPase activity
0.41GO:0140098catalytic activity, acting on RNA
0.46GO:0005730nucleolus
0.37GO:0005737cytoplasm
0.34GO:0005654nucleoplasm
sp|Q8IY42|CD019_HUMAN
Uncharacterized protein C4orf19
Search
0.39GO:0005515protein binding
0.75GO:0030054cell junction
0.70GO:0005654nucleoplasm
sp|Q8IY45|AMN1_HUMAN
Protein AMN1 homolog
Search
AMN1
0.97Antagonist of mitotic exit network 1
0.43GO:0016032viral process
0.42GO:0016874ligase activity
0.42EC:6 GO:0016874
sp|Q8IY47|KBTB2_HUMAN
Kelch repeat and BTB domain-containing protein 2
Search
KBTBD2
0.96Kelch repeat and BTB domain-containing protein 2
0.71GO:0016567protein ubiquitination
0.72GO:0004842ubiquitin-protein transferase activity
0.82GO:0031463Cul3-RING ubiquitin ligase complex
0.30GO:0031224intrinsic component of membrane
0.72KEGG:R03876 GO:0004842
sp|Q8IY49|PAQRA_HUMAN
Monocyte to macrophage differentiation factor 2
Search
MMD2
0.72Monocyte to macrophage differentiation associated
0.61GO:0045666positive regulation of neuron differentiation
0.60GO:0046579positive regulation of Ras protein signal transduction
0.59GO:0045860positive regulation of protein kinase activity
0.56GO:0032880regulation of protein localization
0.50GO:0006468protein phosphorylation
0.45GO:0019835cytolysis
0.44GO:0003007heart morphogenesis
0.37GO:0007165signal transduction
0.50GO:0004672protein kinase activity
0.56GO:0048471perinuclear region of cytoplasm
0.44GO:0005794Golgi apparatus
0.39GO:0098588bounding membrane of organelle
0.38GO:0031984organelle subcompartment
0.30GO:0016021integral component of membrane
sp|Q8IY50|S35F3_HUMAN
Putative thiamine transporter SLC35F3
Search
SLC35F3
0.96Solute carrier family 35 member F3
0.53GO:0015888thiamine transport
0.44GO:0055085transmembrane transport
0.45GO:0022857transmembrane transporter activity
0.30GO:0044425membrane part
sp|Q8IY51|TIGD4_HUMAN
Tigger transposable element-derived protein 4
Search
TIGD4
0.94Tigger transposable element-derived protein 4
0.55GO:0003677DNA binding
0.33GO:0003682chromatin binding
0.37GO:0005634nucleus
0.33GO:0000775chromosome, centromeric region
sp|Q8IY57|YAF2_HUMAN
YY1-associated factor 2
Search
YAF2
0.95YY1-associated factor 2 isoform B
0.70GO:1903507negative regulation of nucleic acid-templated transcription
0.44GO:0045893positive regulation of transcription, DNA-templated
0.44GO:0030900forebrain development
0.43GO:2000113negative regulation of cellular macromolecule biosynthetic process
0.43GO:0043066negative regulation of apoptotic process
0.42GO:0010629negative regulation of gene expression
0.36GO:0070317negative regulation of G0 to G1 transition
0.34GO:0006351transcription, DNA-templated
0.80GO:0003714transcription corepressor activity
0.78GO:0003713transcription coactivator activity
0.48GO:0046872metal ion binding
0.35GO:0005515protein binding
0.43GO:0005654nucleoplasm
0.43GO:0005829cytosol
sp|Q8IY63|AMOL1_HUMAN
Angiomotin-like protein 1
Search
AMOTL1
0.83Angiomotin like 1
0.87GO:0003365establishment of cell polarity involved in ameboidal cell migration
0.85GO:0043536positive regulation of blood vessel endothelial cell migration
0.84GO:0035329hippo signaling
0.40GO:0043534blood vessel endothelial cell migration
0.39GO:0034260negative regulation of GTPase activity
0.39GO:0001702gastrulation with mouth forming second
0.39GO:0040019positive regulation of embryonic development
0.39GO:0042074cell migration involved in gastrulation
0.39GO:0001570vasculogenesis
0.39GO:0016525negative regulation of angiogenesis
0.72GO:0042802identical protein binding
0.40GO:0043532angiostatin binding
0.36GO:0004872receptor activity
0.82GO:0030027lamellipodium
0.81GO:0005923bicellular tight junction
0.80GO:0016324apical plasma membrane
0.80GO:0008180COP9 signalosome
0.72GO:0031410cytoplasmic vesicle
0.39GO:0001726ruffle
0.39GO:0005884actin filament
0.38GO:0009897external side of plasma membrane
0.32GO:0097517contractile actin filament bundle
0.32GO:0042641actomyosin
sp|Q8IY67|RAVR1_HUMAN
Ribonucleoprotein PTB-binding 1
Search
RAVER1
0.92Ribonucleoprotein PTB-binding 1
0.46GO:0000398mRNA splicing, via spliceosome
0.36GO:0018108peptidyl-tyrosine phosphorylation
0.34GO:0022900electron transport chain
0.33GO:0035556intracellular signal transduction
0.59GO:0003723RNA binding
0.36GO:0004713protein tyrosine kinase activity
0.35GO:00515372 iron, 2 sulfur cluster binding
0.34GO:0009055electron transfer activity
0.34GO:0005515protein binding
0.33GO:0030554adenyl nucleotide binding
0.33GO:0032555purine ribonucleotide binding
0.33GO:0008144drug binding
0.33GO:0035639purine ribonucleoside triphosphate binding
0.58GO:0019013viral nucleocapsid
0.51GO:0030529intracellular ribonucleoprotein complex
0.42GO:0005634nucleus
0.33GO:0005737cytoplasm
0.33GO:0005856cytoskeleton
0.30GO:0016020membrane
0.36EC:2.7.10 GO:0004713
sp|Q8IY81|SPB1_HUMAN
pre-rRNA processing protein FTSJ3
Search
FTSJ3
0.97pre-rRNA processing protein FTSJ3
0.73GO:0000453enzyme-directed rRNA 2'-O-methylation
0.49GO:0000463maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49GO:0000466maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.69GO:0008649rRNA methyltransferase activity
0.46GO:0008171O-methyltransferase activity
0.35GO:0003723RNA binding
0.34GO:0005515protein binding
0.77GO:0030688preribosome, small subunit precursor
0.69GO:0005730nucleolus
0.49GO:0030687preribosome, large subunit precursor
0.69EC:2.1.1 GO:0008649
sp|Q8IY82|DRC7_HUMAN
Dynein regulatory complex subunit 7
Search
DRC7
0.93Dynein regulatory complex subunit 7
0.30GO:0005488binding
0.49GO:0005737cytoplasm
0.42GO:0031514motile cilium
0.40GO:0005856cytoskeleton
sp|Q8IY84|NIM1_HUMAN
Serine/threonine-protein kinase NIM1
Search
NIM1K
0.97Serine/threonine-protein kinase NIM1
0.63GO:0006468protein phosphorylation
0.42GO:0035556intracellular signal transduction
0.33GO:0007229integrin-mediated signaling pathway
0.68GO:0004674protein serine/threonine kinase activity
0.55GO:0030554adenyl nucleotide binding
0.54GO:0097367carbohydrate derivative binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.47GO:0000287magnesium ion binding
0.33GO:0005509calcium ion binding
0.41GO:0005634nucleus
0.37GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
0.68EC:2.7.11 GO:0004674
sp|Q8IY85|EFC13_HUMAN
EF-hand calcium-binding domain-containing protein 13
Search
EFCAB13
0.97EF-hand calcium-binding domain-containing protein 13
0.70GO:0005509calcium ion binding
sp|Q8IY92|SLX4_HUMAN
Structure-specific endonuclease subunit SLX4
Search
SLX4
0.61LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4
0.73GO:1904431positive regulation of t-circle formation
0.73GO:0001325formation of extrachromosomal circular DNA
0.73GO:0090737telomere maintenance via telomere trimming
0.72GO:0061820telomeric D-loop disassembly
0.72GO:0072429response to intra-S DNA damage checkpoint signaling
0.71GO:0010792DNA double-strand break processing involved in repair via single-strand annealing
0.69GO:1904357negative regulation of telomere maintenance via telomere lengthening
0.63GO:0006260DNA replication
0.62GO:0000724double-strand break repair via homologous recombination
0.59GO:0043085positive regulation of catalytic activity
0.77GO:00171085'-flap endonuclease activity
0.75GO:00482573'-flap endonuclease activity
0.65GO:0008821crossover junction endodeoxyribonuclease activity
0.60GO:0008047enzyme activator activity
0.38GO:0005515protein binding
0.32GO:0030554adenyl nucleotide binding
0.32GO:0097367carbohydrate derivative binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.32GO:0003676nucleic acid binding
0.80GO:0033557Slx1-Slx4 complex
0.72GO:0070522ERCC4-ERCC1 complex
0.65GO:0000784nuclear chromosome, telomeric region
0.63GO:0048476Holliday junction resolvase complex
0.61GO:0000790nuclear chromatin
0.60GO:0030054cell junction
0.57GO:0005654nucleoplasm
0.56GO:0005829cytosol
0.65EC:3.1.22.4 GO:0008821
sp|Q8IY95|TM192_HUMAN
Transmembrane protein 192
Search
TMEM192
0.80Transmembrane protein 192
0.54GO:0042803protein homodimerization activity
0.59GO:0005765lysosomal membrane
0.58GO:0005770late endosome
0.57GO:0048471perinuclear region of cytoplasm
0.51GO:0005654nucleoplasm
0.38GO:0070062extracellular exosome
0.37GO:0005794Golgi apparatus
0.36GO:0005783endoplasmic reticulum
0.34GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q8IYA2|C144C_HUMAN
Putative coiled-coil domain-containing protein 144C
Search
0.12Putative coiled-coil domain-containing protein 144C
0.62GO:0045599negative regulation of fat cell differentiation
0.56GO:0040015negative regulation of multicellular organism growth
0.56GO:0060259regulation of feeding behavior
0.55GO:0046621negative regulation of organ growth
0.55GO:0046627negative regulation of insulin receptor signaling pathway
0.54GO:0070373negative regulation of ERK1 and ERK2 cascade
0.53GO:0019217regulation of fatty acid metabolic process
0.52GO:0042593glucose homeostasis
0.37GO:0007018microtubule-based movement
0.35GO:0007062sister chromatid cohesion
0.47GO:0005515protein binding
0.40GO:0044877macromolecular complex binding
0.37GO:0003777microtubule motor activity
0.35GO:0032559adenyl ribonucleotide binding
0.35GO:0008144drug binding
0.35GO:0035639purine ribonucleoside triphosphate binding
0.33GO:0003677DNA binding
0.70GO:0005813centrosome
0.53GO:0005884actin filament
0.41GO:0005829cytosol
0.38GO:0016459myosin complex
0.34GO:0005694chromosome
0.30GO:0016020membrane
sp|Q8IYA6|CKP2L_HUMAN
Cytoskeleton-associated protein 2-like
Search
CKAP2L
0.68Cytoskeleton associated protein 2 like
0.42GO:0001660fever generation
0.41GO:0051781positive regulation of cell division
0.39GO:0010469regulation of receptor activity
0.39GO:0006955immune response
0.34GO:0006368transcription elongation from RNA polymerase II promoter
0.34GO:0016570histone modification
0.42GO:0005149interleukin-1 receptor binding
0.40GO:0005125cytokine activity
0.80GO:0072686mitotic spindle
0.77GO:0005813centrosome
0.68GO:0005829cytosol
0.48GO:0000922spindle pole
0.39GO:0005615extracellular space
0.34GO:0016593Cdc73/Paf1 complex
sp|Q8IYA7|MKX_HUMAN
Homeobox protein Mohawk
Search
MKX
0.97Homeobox protein mohawk A
0.55GO:1903506regulation of nucleic acid-templated transcription
0.55GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.42GO:0061061muscle structure development
0.40GO:0048513animal organ development
0.40GO:1904888cranial skeletal system development
0.40GO:0048706embryonic skeletal system development
0.39GO:0030154cell differentiation
0.39GO:0009653anatomical structure morphogenesis
0.39GO:1902679negative regulation of RNA biosynthetic process
0.61GO:0043565sequence-specific DNA binding
0.37GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37GO:0001085RNA polymerase II transcription factor binding
0.37GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36GO:0001012RNA polymerase II regulatory region DNA binding
0.35GO:0003690double-stranded DNA binding
0.59GO:0005634nucleus
0.34GO:0005667transcription factor complex
sp|Q8IYA8|IHO1_HUMAN
Interactor of HORMAD1 protein 1
Search
CCDC36
0.96Coiled-coil domain-containing protein 36
0.85GO:0042138meiotic DNA double-strand break formation
0.75GO:0060629regulation of homologous chromosome segregation
0.69GO:0007129synapsis
0.67GO:0048477oogenesis
0.66GO:0007283spermatogenesis
0.65GO:0006310DNA recombination
0.65GO:0000794condensed nuclear chromosome
sp|Q8IYB0|YK038_HUMAN
Putative uncharacterized protein MGC39545
Search
sp|Q8IYB1|M21D2_HUMAN
Protein MB21D2
Search
MB21D2
0.95Mab-21 domain containing 2
0.81GO:0045296cadherin binding
0.74GO:0032403protein complex binding
0.30GO:0031224intrinsic component of membrane
sp|Q8IYB3|SRRM1_HUMAN
Serine/arginine repetitive matrix protein 1
Search
SRRM1
0.76Serine and arginine repetitive matrix 1
0.68GO:0006397mRNA processing
0.38GO:0008380RNA splicing
0.36GO:0006369termination of RNA polymerase II transcription
0.35GO:0071427mRNA-containing ribonucleoprotein complex export from nucleus
0.35GO:0031123RNA 3'-end processing
0.35GO:0051028mRNA transport
0.35GO:0006405RNA export from nucleus
0.36GO:0003723RNA binding
0.35GO:0005515protein binding
0.34GO:0003677DNA binding
0.54GO:0016607nuclear speck
0.52GO:0071013catalytic step 2 spliceosome
0.39GO:0016363nuclear matrix
0.34GO:0005829cytosol
0.30GO:0016020membrane
sp|Q8IYB4|PEX5R_HUMAN
PEX5-related protein
Search
PEX5L
0.97Peroxisomal biogenesis factor 5 like
0.66GO:0016560protein import into peroxisome matrix, docking
0.49GO:0043949regulation of cAMP-mediated signaling
0.43GO:0045185maintenance of protein location
0.42GO:0042391regulation of membrane potential
0.42GO:0051461positive regulation of corticotropin secretion
0.40GO:0045055regulated exocytosis
0.36GO:0098655cation transmembrane transport
0.86GO:0000268peroxisome targeting sequence binding
0.71GO:0031267small GTPase binding
0.41GO:0005221intracellular cyclic nucleotide activated cation channel activity
0.74GO:0043235receptor complex
0.63GO:0031903microbody membrane
0.62GO:0044439peroxisomal part
0.56GO:0005829cytosol
0.43GO:0030425dendrite
0.42GO:0017071intracellular cyclic nucleotide activated cation channel complex
0.40GO:0051286cell tip
0.39GO:0048471perinuclear region of cytoplasm
sp|Q8IYB5|SMAP1_HUMAN
Stromal membrane-associated protein 1
Search
SMAP1
0.96Small ArfGAP 1
0.76GO:0043547positive regulation of GTPase activity
0.75GO:2000369regulation of clathrin-dependent endocytosis
0.74GO:0045648positive regulation of erythrocyte differentiation
0.36GO:0031532actin cytoskeleton reorganization
0.76GO:0005096GTPase activator activity
0.68GO:0030276clathrin binding
0.53GO:0046872metal ion binding
0.44GO:0005737cytoplasm
sp|Q8IYB7|DI3L2_HUMAN
DIS3-like exonuclease 2
Search
DIS3L2
0.93DIS3 like 3'-5' exoribonuclease 2
0.81GO:0010587miRNA catabolic process
0.68GO:0051306mitotic sister chromatid separation
0.68GO:0090503RNA phosphodiester bond hydrolysis, exonucleolytic
0.64GO:0000291nuclear-transcribed mRNA catabolic process, exonucleolytic
0.63GO:0019827stem cell population maintenance
0.61GO:0008285negative regulation of cell proliferation
0.56GO:0006364rRNA processing
0.54GO:0048793pronephros development
0.50GO:0006914autophagy
0.72GO:00001753'-5'-exoribonuclease activity
0.65GO:0008266poly(U) RNA binding
0.51GO:0000287magnesium ion binding
0.72GO:0000932P-body
0.64GO:0000178exosome (RNase complex)
0.72EC:3.1.13 GO:0000175
sp|Q8IYB8|SUV3_HUMAN
ATP-dependent RNA helicase SUPV3L1, mitochondrial
Search
SUPV3L1
0.90ATP-dependent RNA helicase DDX55
0.62GO:0035945mitochondrial ncRNA surveillance
0.62GO:0035946mitochondrial mRNA surveillance
0.61GO:0000965mitochondrial RNA 3'-end processing
0.61GO:0000962positive regulation of mitochondrial RNA catabolic process
0.61GO:0000958mitochondrial mRNA catabolic process
0.59GO:0070827chromatin maintenance
0.58GO:0070584mitochondrion morphogenesis
0.56GO:0030307positive regulation of cell growth
0.53GO:0043066negative regulation of apoptotic process
0.49GO:0032392DNA geometric change
0.58GO:0016817hydrolase activity, acting on acid anhydrides
0.53GO:0003725double-stranded RNA binding
0.51GO:0042803protein homodimerization activity
0.46GO:0140098catalytic activity, acting on RNA
0.46GO:0140097catalytic activity, acting on DNA
0.42GO:0003677DNA binding
0.35GO:0032559adenyl ribonucleotide binding
0.35GO:0008144drug binding
0.35GO:0035639purine ribonucleoside triphosphate binding
0.61GO:0045025mitochondrial degradosome
0.56GO:0042645mitochondrial nucleoid
0.45GO:0005634nucleus
0.58EC:3.6 GO:0016817
sp|Q8IYB9|ZN595_HUMAN
Zinc finger protein 595
Search
0.75Zinc finger protein 732
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.41GO:0097659nucleic acid-templated transcription
0.39GO:0010467gene expression
0.39GO:0034645cellular macromolecule biosynthetic process
0.54GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.45GO:0005622intracellular
0.40GO:0043227membrane-bounded organelle
sp|Q8IYD1|ERF3B_HUMAN
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B
Search
GSPT1
0.91G1 to S phase transition 2
0.55GO:0006415translational termination
0.52GO:0008213protein alkylation
0.49GO:0043414macromolecule methylation
0.48GO:0002181cytoplasmic translation
0.68GO:0003924GTPase activity
0.66GO:0032550purine ribonucleoside binding
0.66GO:0019001guanyl nucleotide binding
0.55GO:0008079translation termination factor activity
0.54GO:0032555purine ribonucleotide binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0018444translation release factor complex
0.44GO:0005829cytosol
sp|Q8IYD2|KLD8A_HUMAN
Kelch domain-containing protein 8A
Search
KLHDC8A
0.97Kelch domain-containing protein 8A
0.65GO:0016567protein ubiquitination
0.41GO:0051301cell division
0.41GO:0007049cell cycle
0.36GO:0006468protein phosphorylation
0.66GO:0004842ubiquitin-protein transferase activity
0.36GO:0004672protein kinase activity
0.35GO:0030554adenyl nucleotide binding
0.34GO:0097367carbohydrate derivative binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.74GO:0031463Cul3-RING ubiquitin ligase complex
0.54GO:0005829cytosol
0.46GO:0030496midbody
0.30GO:0031224intrinsic component of membrane
0.66KEGG:R03876 GO:0004842
sp|Q8IYD8|FANCM_HUMAN
Fanconi anemia group M protein
Search
FANCM
0.84Fanconi anemia complementation group M
0.67GO:0000712resolution of meiotic recombination intermediates
0.65GO:0031297replication fork processing
0.63GO:0090305nucleic acid phosphodiester bond hydrolysis
0.39GO:0036297interstrand cross-link repair
0.63GO:0004518nuclease activity
0.60GO:0003682chromatin binding
0.55GO:0003677DNA binding
0.52GO:0030554adenyl nucleotide binding
0.51GO:0032555purine ribonucleotide binding
0.51GO:0008144drug binding
0.51GO:0035639purine ribonucleoside triphosphate binding
0.38GO:0004386helicase activity
0.36GO:0005515protein binding
0.67GO:0071821FANCM-MHF complex
0.66GO:0043240Fanconi anaemia nuclear complex
0.30GO:0031224intrinsic component of membrane
0.63EC:3.1 GO:0004518
sp|Q8IYD9|LAS2_HUMAN
Lung adenoma susceptibility protein 2
Search
0.86Lung adenoma susceptibility protein 2
0.68GO:0008285negative regulation of cell proliferation
0.53GO:0005515protein binding
0.36GO:0003676nucleic acid binding
0.56GO:0005576extracellular region
sp|Q8IYE0|CC146_HUMAN
Coiled-coil domain-containing protein 146
Search
CCDC146
0.97Coiled-coil domain-containing protein 146
0.38GO:0005515protein binding
0.82GO:0005814centriole
sp|Q8IYE1|CCD13_HUMAN
Coiled-coil domain-containing protein 13
Search
CCDC13
0.95LOW QUALITY PROTEIN: coiled-coil domain-containing protein 13
0.84GO:1905515non-motile cilium assembly
0.83GO:0031122cytoplasmic microtubule organization
0.64GO:0006974cellular response to DNA damage stimulus
0.33GO:0000413protein peptidyl-prolyl isomerization
0.32GO:0006457protein folding
0.32GO:0006886intracellular protein transport
0.32GO:0061025membrane fusion
0.32GO:0016192vesicle-mediated transport
0.37GO:0005515protein binding
0.33GO:0003755peptidyl-prolyl cis-trans isomerase activity
0.85GO:0034451centriolar satellite
0.68GO:0005829cytosol
0.61GO:0005634nucleus
0.41GO:0042995cell projection
0.30GO:0016020membrane
0.33EC:5.2.1.8 GO:0003755
sp|Q8IYF1|ELOA2_HUMAN
Elongin-A2
Search
ELOA
0.68Transcription elongation factor B polypeptide 3
0.70GO:0006357regulation of transcription by RNA polymerase II
0.49GO:0006414translational elongation
0.48GO:0006368transcription elongation from RNA polymerase II promoter
0.42GO:0032784regulation of DNA-templated transcription, elongation
0.37GO:0055114oxidation-reduction process
0.32GO:0006508proteolysis
0.50GO:0003746translation elongation factor activity
0.39GO:0005515protein binding
0.37GO:0016491oxidoreductase activity
0.37GO:0003735structural constituent of ribosome
0.32GO:0008233peptidase activity
0.85GO:0070449elongin complex
0.37GO:0005840ribosome
0.37EC:1 GO:0016491
sp|Q8IYF3|TEX11_HUMAN
Testis-expressed protein 11
Search
TEX11
0.97Testis-expressed protein 11
0.78GO:0051321meiotic cell cycle
0.56GO:0035822gene conversion
0.55GO:0070193synaptonemal complex organization
0.54GO:0008584male gonad development
0.53GO:0009566fertilization
0.53GO:0035825homologous recombination
0.52GO:0048232male gamete generation
0.52GO:0051304chromosome separation
0.52GO:0022412cellular process involved in reproduction in multicellular organism
0.51GO:0043066negative regulation of apoptotic process
0.36GO:0005515protein binding
0.32GO:0003723RNA binding
0.57GO:0000801central element
0.30GO:0031224intrinsic component of membrane
sp|Q8IYG6|LRC56_HUMAN
Leucine-rich repeat-containing protein 56
Search
LRRC56
0.94LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 56
0.59GO:0070507regulation of microtubule cytoskeleton organization
0.48GO:0007165signal transduction
sp|Q8IYH5|ZZZ3_HUMAN
ZZ-type zinc finger-containing protein 3
Search
ZZZ3
0.97ZZ-type zinc finger-containing protein 3
0.34GO:0006351transcription, DNA-templated
0.34GO:2001141regulation of RNA biosynthetic process
0.34GO:2000112regulation of cellular macromolecule biosynthetic process
0.34GO:0010468regulation of gene expression
0.62GO:0008270zinc ion binding
0.54GO:0003677DNA binding
0.34GO:0005515protein binding
0.55GO:0005671Ada2/Gcn5/Ada3 transcription activator complex
0.50GO:0005730nucleolus
sp|Q8IYI0|CT196_HUMAN
Uncharacterized protein C20orf196
Search
sp|Q8IYI6|EXOC8_HUMAN
Exocyst complex component 8
Search
EXOC8
0.96Exocyst complex component 8
0.76GO:0006887exocytosis
0.61GO:0022617extracellular matrix disassembly
0.59GO:0007032endosome organization
0.52GO:0051601exocyst localization
0.49GO:0048278vesicle docking
0.45GO:0043623cellular protein complex assembly
0.39GO:0015031protein transport
0.36GO:0016241regulation of macroautophagy
0.32GO:0055114oxidation-reduction process
0.61GO:0017160Ral GTPase binding
0.35GO:0035091phosphatidylinositol binding
0.35GO:0031418L-ascorbic acid binding
0.34GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33GO:0005506iron ion binding
0.78GO:0000145exocyst
0.56GO:0005770late endosome
0.50GO:0005829cytosol
0.44GO:0030426growth cone
0.42GO:0048471perinuclear region of cytoplasm
0.39GO:0031252cell leading edge
0.36GO:0097546ciliary base
0.36GO:00977319+0 non-motile cilium
0.34GO:0005886plasma membrane
0.34EC:1.14 GO:0016705
sp|Q8IYI8|ZN440_HUMAN
Zinc finger protein 440
Search
0.87Zinc finger protein 440
0.55GO:2000112regulation of cellular macromolecule biosynthetic process
0.55GO:1903506regulation of nucleic acid-templated transcription
0.55GO:0010468regulation of gene expression
0.41GO:0097659nucleic acid-templated transcription
0.40GO:0010467gene expression
0.39GO:0034645cellular macromolecule biosynthetic process
0.51GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.41GO:0005515protein binding
0.36GO:0003700DNA binding transcription factor activity
0.44GO:0005622intracellular
0.40GO:0043227membrane-bounded organelle
sp|Q8IYJ0|PIANP_HUMAN
PILR alpha-associated neural protein
Search
PIANP
0.97PILR alpha-associated neural protein isoform a
0.36GO:0050776regulation of immune response
0.45GO:0016323basolateral plasma membrane
0.44GO:0005912adherens junction
0.30GO:0031224intrinsic component of membrane
sp|Q8IYJ1|CPNE9_HUMAN
Copine-9
Search
CPNE9
0.81Copine VIII
0.85GO:1903861positive regulation of dendrite extension
0.37GO:0035335peptidyl-tyrosine dephosphorylation
0.37GO:0004725protein tyrosine phosphatase activity
0.35GO:0046872metal ion binding
0.34GO:0003676nucleic acid binding
0.55GO:0043025neuronal cell body
0.53GO:0043005neuron projection
0.45GO:0070062extracellular exosome
0.37EC:3.1.3.48 GO:0004725
sp|Q8IYJ2|CJ067_HUMAN
Uncharacterized protein C10orf67, mitochondrial
Search
sp|Q8IYJ3|SYTL1_HUMAN
Synaptotagmin-like protein 1
Search
SYTL1
0.97Synaptotagmin like 1
0.77GO:0006887exocytosis
0.64GO:0006886intracellular protein transport
0.52GO:0017158regulation of calcium ion-dependent exocytosis
0.51GO:0048489synaptic vesicle transport
0.51GO:0099504synaptic vesicle cycle
0.51GO:0006906vesicle fusion
0.50GO:0099643signal release from synapse
0.50GO:0099531presynaptic process involved in chemical synaptic transmission
0.48GO:0006836neurotransmitter transport
0.47GO:0001505regulation of neurotransmitter levels
0.78GO:0017137Rab GTPase binding
0.51GO:0019905syntaxin binding
0.50GO:0005544calcium-dependent phospholipid binding
0.50GO:0030276clathrin binding
0.46GO:0005509calcium ion binding
0.45GO:0042043neurexin family protein binding
0.36GO:0001786phosphatidylserine binding
0.35GO:0005546phosphatidylinositol-4,5-bisphosphate binding
0.35GO:0019902phosphatase binding
0.50GO:0070382exocytic vesicle
0.48GO:0098793presynapse
0.46GO:0005886plasma membrane
0.45GO:0042470melanosome
0.42GO:0019898extrinsic component of membrane
0.40GO:0070062extracellular exosome
0.37GO:0005902microvillus
0.36GO:0120038plasma membrane bounded cell projection part
0.30GO:0016021integral component of membrane
sp|Q8IYK2|CC105_HUMAN
Coiled-coil domain-containing protein 105
Search
CCDC105
0.97Coiled-coil domain-containing protein 105
0.49GO:0006508proteolysis
0.59GO:0004197cysteine-type endopeptidase activity
0.63GO:0070062extracellular exosome
0.59EC:3.4.22 GO:0004197
sp|Q8IYK4|GT252_HUMAN
Procollagen galactosyltransferase 2
Search
COLGALT2
0.96Procollagen galactosyltransferase 2
0.47GO:1904028positive regulation of collagen fibril organization
0.33GO:0006412translation
0.59GO:0016757transferase activity, transferring glycosyl groups
0.39GO:0140096catalytic activity, acting on a protein
0.34GO:0005515protein binding
0.34GO:0003735structural constituent of ribosome
0.46GO:0005788endoplasmic reticulum lumen
0.33GO:0005840ribosome
0.30GO:0016021integral component of membrane
0.59EC:2.4 GO:0016757
sp|Q8IYK8|REM2_HUMAN
GTP-binding protein REM 2
Search
REM2
0.92GTP-binding protein RAD
0.79GO:1901841regulation of high voltage-gated calcium channel activity
0.73GO:1901386negative regulation of voltage-gated calcium channel activity
0.61GO:0007165signal transduction
0.35GO:0071542dopaminergic neuron differentiation
0.34GO:0016339calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.34GO:0030308negative regulation of cell growth
0.33GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.32GO:1903506regulation of nucleic acid-templated transcription
0.32GO:2000112regulation of cellular macromolecule biosynthetic process
0.32GO:0010468regulation of gene expression
0.67GO:0003924GTPase activity
0.66GO:0032550purine ribonucleoside binding
0.66GO:0019001guanyl nucleotide binding
0.54GO:0032555purine ribonucleotide binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.36GO:0005246calcium channel regulator activity
0.36GO:0005516calmodulin binding
0.33GO:0005509calcium ion binding
0.32GO:0004930G-protein coupled receptor activity
0.32GO:0003700DNA binding transcription factor activity
0.36GO:0005886plasma membrane
0.32GO:0005634nucleus
0.30GO:0016021integral component of membrane
sp|Q8IYL2|TRM44_HUMAN
Probable tRNA (uracil-O(2)-)-methyltransferase
Search
TRMT44
0.91Methyltransferase like 19
0.63GO:0032259methylation
0.44GO:0006400tRNA modification
0.37GO:0044260cellular macromolecule metabolic process
0.63GO:0008168methyltransferase activity
0.52GO:0046872metal ion binding
0.43GO:0140101catalytic activity, acting on a tRNA
0.34GO:0005737cytoplasm
0.63EC:2.1.1 GO:0008168
sp|Q8IYL3|CA174_HUMAN
UPF0688 protein C1orf174
Search
sp|Q8IYL9|PSYR_HUMAN
Psychosine receptor
Search
GPR65
0.97Psychosine receptor
0.71GO:0007186G-protein coupled receptor signaling pathway
0.62GO:0010447response to acidic pH
0.59GO:0051496positive regulation of stress fiber assembly
0.58GO:0090630activation of GTPase activity
0.58GO:0019933cAMP-mediated signaling
0.54GO:0031532actin cytoskeleton reorganization
0.52GO:0035025positive regulation of Rho protein signal transduction
0.50GO:0007204positive regulation of cytosolic calcium ion concentration
0.46GO:0072144glomerular mesangial cell development
0.45GO:0060055angiogenesis involved in wound healing
0.72GO:0004930G-protein coupled receptor activity
0.36GO:0001614purinergic nucleotide receptor activity
0.34GO:0001653peptide receptor activity
0.34GO:0030594neurotransmitter receptor activity
0.44GO:0005887integral component of plasma membrane
0.38GO:0005622intracellular
sp|Q8IYM0|F186B_HUMAN
Protein FAM186B
Search
sp|Q8IYM1|SEP12_HUMAN
Septin-12
Search
SEPT12
0.92neuronal-specific septin-3-like isoform X2
0.54GO:0007049cell cycle
0.53GO:0097722sperm motility
0.38GO:0007283spermatogenesis
0.37GO:0051301cell division
0.36GO:0030154cell differentiation
0.33GO:0002098tRNA wobble uridine modification
0.66GO:0032550purine ribonucleoside binding
0.65GO:0019001guanyl nucleotide binding
0.54GO:0032555purine ribonucleotide binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0042802identical protein binding
0.47GO:0046983protein dimerization activity
0.36GO:0035091phosphatidylinositol binding
0.58GO:0097227sperm annulus
0.56GO:0031105septin complex
0.54GO:0030496midbody
0.52GO:0048471perinuclear region of cytoplasm
0.51GO:0005819spindle
0.37GO:0097517contractile actin filament bundle
0.37GO:0032154cleavage furrow
0.37GO:0042641actomyosin
0.34GO:0033588Elongator holoenzyme complex
0.33GO:0045202synapse
sp|Q8IYM2|SLN12_HUMAN
Schlafen family member 12
Search
0.89Schlafen family member 12 like
0.52GO:0036345platelet maturation
0.49GO:2000134negative regulation of G1/S transition of mitotic cell cycle
0.46GO:0016075rRNA catabolic process
0.46GO:0051607defense response to virus
0.45GO:0006402mRNA catabolic process
0.44GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
0.38GO:0071287cellular response to manganese ion
0.38GO:0071286cellular response to magnesium ion
0.38GO:0008285negative regulation of cell proliferation
0.35GO:0050868negative regulation of T cell activation
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.45GO:0043022ribosome binding
0.44GO:0004521endoribonuclease activity
0.43GO:0000049tRNA binding
0.34GO:0003735structural constituent of ribosome
0.33GO:0005515protein binding
0.50GO:0005634nucleus
0.40GO:0016235aggresome
0.37GO:0005737cytoplasm
0.37GO:0043233organelle lumen
0.35GO:0044446intracellular organelle part
0.34GO:0030529intracellular ribonucleoprotein complex
0.34GO:0043232intracellular non-membrane-bounded organelle
0.30GO:0016020membrane
sp|Q8IYM9|TRI22_HUMAN
E3 ubiquitin-protein ligase TRIM22
Search
0.92tripartite motif-containing protein 6
0.56GO:0009615response to virus
0.56GO:0045087innate immune response
0.55GO:0002252immune effector process
0.54GO:0006914autophagy
0.54GO:0016567protein ubiquitination
0.54GO:0098542defense response to other organism
0.52GO:0051092positive regulation of NF-kappaB transcription factor activity
0.52GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
0.52GO:0070206protein trimerization
0.49GO:0031325positive regulation of cellular metabolic process
0.62GO:0008270zinc ion binding
0.54GO:0004842ubiquitin-protein transferase activity
0.50GO:0030674protein binding, bridging
0.50GO:0019901protein kinase binding
0.43GO:0038187pattern recognition receptor activity
0.40GO:0061659ubiquitin-like protein ligase activity
0.39GO:0016874ligase activity
0.38GO:0038023signaling receptor activity
0.38GO:0008134transcription factor binding
0.35GO:0003714transcription corepressor activity
0.46GO:0016604nuclear body
0.44GO:0005794Golgi apparatus
0.42GO:0000932P-body
0.39GO:0005829cytosol
0.35GO:1990462omegasome
0.39EC:6 GO:0016874
0.54KEGG:R03876 GO:0004842
sp|Q8IYN0|ZN100_HUMAN
Zinc finger protein 100
Search
0.85Zinc finger protein 680
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.43GO:0097659nucleic acid-templated transcription
0.41GO:0010467gene expression
0.40GO:0034645cellular macromolecule biosynthetic process
0.54GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.45GO:0005622intracellular
0.42GO:0043227membrane-bounded organelle
sp|Q8IYN2|TCAL8_HUMAN
Transcription elongation factor A protein-like 8
Search
TCEAL8
0.97Transcription elongation factor A like 8
0.65GO:0006414translational elongation
0.55GO:0006357regulation of transcription by RNA polymerase II
0.41GO:0097659nucleic acid-templated transcription
0.66GO:0050699WW domain binding
0.66GO:0003746translation elongation factor activity
0.49GO:0005634nucleus
sp|Q8IYN6|UBAD2_HUMAN
UBA-like domain-containing protein 2
Search
UBALD2
0.96UBA like domain containing 2
0.43GO:0030097hemopoiesis
0.43GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
0.43GO:0018108peptidyl-tyrosine phosphorylation
0.41GO:0030154cell differentiation
0.43GO:0004714transmembrane receptor protein tyrosine kinase activity
0.37GO:0030554adenyl nucleotide binding
0.37GO:0097367carbohydrate derivative binding
0.37GO:0008144drug binding
0.37GO:0035639purine ribonucleoside triphosphate binding
0.30GO:0031224intrinsic component of membrane
0.43EC:2.7.10.1 GO:0004714
sp|Q8IYP2|PRS58_HUMAN
Serine protease 58
Search
PRSS58
0.94cationic trypsin-3
0.61GO:0006508proteolysis
0.44GO:2000344positive regulation of acrosome reaction
0.43GO:0007339binding of sperm to zona pellucida
0.43GO:0070613regulation of protein processing
0.41GO:0045745positive regulation of G-protein coupled receptor protein signaling pathway
0.41GO:0070997neuron death
0.41GO:0016477cell migration
0.40GO:0051604protein maturation
0.39GO:0032501multicellular organismal process
0.39GO:0042060wound healing
0.69GO:0004252serine-type endopeptidase activity
0.37GO:0005509calcium ion binding
0.35GO:0005044scavenger receptor activity
0.34GO:0097655serpin family protein binding
0.33GO:0046982protein heterodimerization activity
0.33GO:0008083growth factor activity
0.32GO:0004128cytochrome-b5 reductase activity, acting on NAD(P)H
0.45GO:0005576extracellular region
0.44GO:0030141secretory granule
0.43GO:0097223sperm part
0.38GO:0005794Golgi apparatus
0.34GO:0097180serine protease inhibitor complex
0.34GO:0045177apical part of cell
0.33GO:0005634nucleus
0.33GO:0005783endoplasmic reticulum
0.32GO:0043233organelle lumen
0.32GO:0005739mitochondrion
0.69EC:3.4.21 GO:0004252
sp|Q8IYP9|ZDH23_HUMAN
Palmitoyltransferase ZDHHC23
Search
ZDHHC23
0.55Palmitoyltransferase
0.58GO:0018345protein palmitoylation
0.57GO:0072659protein localization to plasma membrane
0.79GO:0019706protein-cysteine S-palmitoyltransferase activity
0.30GO:0031224intrinsic component of membrane
0.79EC:2.3.1.225 GO:0019706
sp|Q8IYQ7|THNS1_HUMAN
Threonine synthase-like 1
Search
THNSL1
0.97Threonine synthase like 1
0.59GO:0006520cellular amino acid metabolic process
0.65GO:0030170pyridoxal phosphate binding
0.38GO:0004795threonine synthase activity
0.30GO:0031224intrinsic component of membrane
0.38EC:4.2.3.1 GO:0004795
sp|Q8IYR0|CF206_HUMAN
Cilia- and flagella-associated protein 206
Search
CFAP206
0.80CMP-sialic acid transporter
0.65GO:0035082axoneme assembly
0.65GO:0003341cilium movement
0.36GO:0009132nucleoside diphosphate metabolic process
0.35GO:0006518peptide metabolic process
0.35GO:0043604amide biosynthetic process
0.34GO:0044267cellular protein metabolic process
0.34GO:1901566organonitrogen compound biosynthetic process
0.34GO:0010467gene expression
0.34GO:0009059macromolecule biosynthetic process
0.40GO:0005515protein binding
0.36GO:0030145manganese ion binding
0.35GO:0000287magnesium ion binding
0.35GO:0003735structural constituent of ribosome
0.34GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0.79GO:0031514motile cilium
0.74GO:0097649A axonemal microtubule
0.73GO:0001534radial spoke
0.35GO:0005840ribosome
0.34EC:3.6.1 GO:0016818
sp|Q8IYR2|SMYD4_HUMAN
SET and MYND domain-containing protein 4
Search
SMYD4
0.88SET and MYND domain-containing protein 4
0.61GO:0032259methylation
0.39GO:0042051compound eye photoreceptor development
0.33GO:0055114oxidation-reduction process
0.62GO:0008168methyltransferase activity
0.53GO:0046872metal ion binding
0.34GO:0016620oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.35GO:0005634nucleus
0.33GO:0005737cytoplasm
0.30GO:0044425membrane part
0.62EC:2.1.1 GO:0008168
sp|Q8IYR6|TEFF1_HUMAN
Tomoregulin-1
Search
0.97Transmembrane protein with EGF like and two follistatin like domains 1
0.41GO:0045720negative regulation of integrin biosynthetic process
0.40GO:0051497negative regulation of stress fiber assembly
0.40GO:0090505epiboly involved in wound healing
0.39GO:0030336negative regulation of cell migration
0.38GO:0016477cell migration
0.37GO:0007275multicellular organism development
0.33GO:0035023regulation of Rho protein signal transduction
0.32GO:0003723RNA binding
0.35GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IYS0|GRM1C_HUMAN
GRAM domain-containing protein 1C
Search
GRAMD1C
0.97GRAM domain-containing protein 1C
0.34GO:0005515protein binding
0.30GO:0044425membrane part
sp|Q8IYS1|P20D2_HUMAN
Peptidase M20 domain-containing protein 2
Search
PM20D2
0.95Peptidase M20 domain-containing protein 2
0.55GO:0032268regulation of cellular protein metabolic process
0.50GO:0006508proteolysis
0.35GO:0001522pseudouridine synthesis
0.34GO:0042254ribosome biogenesis
0.61GO:0016805dipeptidase activity
0.36GO:0030515snoRNA binding
0.56GO:0005654nucleoplasm
0.39GO:0070062extracellular exosome
0.61EC:3.4.13 GO:0016805
sp|Q8IYS2|K2013_HUMAN
Uncharacterized protein KIAA2013
Search
0.35GO:0009190cyclic nucleotide biosynthetic process
0.34GO:0046068cGMP metabolic process
0.34GO:0035556intracellular signal transduction
0.33GO:0009152purine ribonucleotide biosynthetic process
0.35GO:0016849phosphorus-oxygen lyase activity
0.34GO:0009975cyclase activity
0.33GO:1901265nucleoside phosphate binding
0.32GO:0036094small molecule binding
0.32GO:0005622intracellular
0.30GO:0031224intrinsic component of membrane
0.35EC:4.6 GO:0016849
sp|Q8IYS4|CP071_HUMAN
Uncharacterized protein C16orf71
Search
sp|Q8IYS5|OSCAR_HUMAN
Osteoclast-associated immunoglobulin-like receptor
Search
OSCAR
0.97Osteoclast-associated receptor isoform 3 (Predicted)
0.59GO:0043312neutrophil degranulation
0.50GO:0050776regulation of immune response
0.61GO:1904724tertiary granule lumen
0.61GO:0035580specific granule lumen
0.61GO:0070062extracellular exosome
0.46GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q8IYS8|BD1L2_HUMAN
Biorientation of chromosomes in cell division protein 1-like 2
Search
0.63GO:0051301cell division
0.51GO:0071962mitotic sister chromatid cohesion, centromeric
0.51GO:1990758mitotic sister chromatid biorientation
0.49GO:0071459protein localization to chromosome, centromeric region
0.48GO:0032515negative regulation of phosphoprotein phosphatase activity
0.48GO:0031297replication fork processing
0.41GO:0006974cellular response to DNA damage stimulus
0.36GO:0010469regulation of receptor activity
0.50GO:0051721protein phosphatase 2A binding
0.48GO:0004864protein phosphatase inhibitor activity
0.37GO:0005179hormone activity
0.33GO:0003677DNA binding
0.50GO:0000777condensed chromosome kinetochore
0.48GO:0005815microtubule organizing center
0.48GO:0005876spindle microtubule
0.47GO:0000922spindle pole
0.43GO:0005654nucleoplasm
0.36GO:0005737cytoplasm
0.35GO:0005576extracellular region
sp|Q8IYT1|FA71A_HUMAN
Protein FAM71A
Search
sp|Q8IYT2|CMTR2_HUMAN
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2
Search
CMTR2
0.97FtsJ methyltransferase domain-containing protein 1
0.64GO:0097310cap2 mRNA methylation
0.53GO:00063707-methylguanosine mRNA capping
0.36GO:0007424open tracheal system development
0.33GO:0035239tube morphogenesis
0.32GO:0016477cell migration
0.31GO:0055114oxidation-reduction process
0.63GO:0008168methyltransferase activity
0.46GO:0140098catalytic activity, acting on RNA
0.32GO:0016491oxidoreductase activity
0.46GO:0005634nucleus
0.40GO:0005737cytoplasm
0.32GO:0012505endomembrane system
0.32GO:0031967organelle envelope
0.32GO:0043234protein complex
0.30GO:0016020membrane
0.63EC:2.1.1 GO:0008168
sp|Q8IYT3|CC170_HUMAN
Coiled-coil domain-containing protein 170
Search
CCDC170
0.97Coiled-coil domain-containing protein 170
0.50GO:0005515protein binding
sp|Q8IYT4|KATL2_HUMAN
Katanin p60 ATPase-containing subunit A-like 2
Search
KATNAL2
0.93Katanin p60 ATPase-containing subunit A-like 2
0.78GO:0051013microtubule severing
0.79GO:0008568microtubule-severing ATPase activity
0.68GO:0008017microtubule binding
0.54GO:0030554adenyl nucleotide binding
0.53GO:0097367carbohydrate derivative binding
0.53GO:0008144drug binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.73GO:0000922spindle pole
0.68GO:0005874microtubule
0.47GO:0005737cytoplasm
0.41GO:0005634nucleus
0.30GO:0031224intrinsic component of membrane
0.79EC:3.6.4.3 GO:0008568
sp|Q8IYT8|ULK2_HUMAN
Serine/threonine-protein kinase ULK2
Search
ULK2
0.91Unc-51 like autophagy activating kinase 2
0.71GO:0075044autophagy of host cells involved in interaction with symbiont
0.67GO:0048667cell morphogenesis involved in neuron differentiation
0.67GO:0048812neuron projection morphogenesis
0.64GO:0046777protein autophosphorylation
0.64GO:0048588developmental cell growth
0.63GO:0061564axon development
0.63GO:0010769regulation of cell morphogenesis involved in differentiation
0.63GO:0010975regulation of neuron projection development
0.63GO:0060560developmental growth involved in morphogenesis
0.59GO:0061387regulation of extent of cell growth
0.70GO:0004674protein serine/threonine kinase activity
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.35GO:0005515protein binding
0.34GO:0044877macromolecular complex binding
0.66GO:0034045phagophore assembly site membrane
0.36GO:0097635extrinsic component of autophagosome membrane
0.36GO:0097629extrinsic component of omegasome membrane
0.35GO:0032045guanyl-nucleotide exchange factor complex
0.35GO:1990316Atg1/ULK1 kinase complex
0.34GO:0005829cytosol
0.70EC:2.7.11 GO:0004674
sp|Q8IYU2|HACE1_HUMAN
E3 ubiquitin-protein ligase HACE1
Search
HACE1
0.93HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
0.72GO:0016567protein ubiquitination
0.64GO:0007030Golgi organization
0.61GO:0030334regulation of cell migration
0.60GO:0006511ubiquitin-dependent protein catabolic process
0.55GO:0061025membrane fusion
0.73GO:0004842ubiquitin-protein transferase activity
0.66GO:0048365Rac GTPase binding
0.63GO:0017137Rab GTPase binding
0.50GO:0061659ubiquitin-like protein ligase activity
0.49GO:0016874ligase activity
0.61GO:0016604nuclear body
0.58GO:0000139Golgi membrane
0.56GO:0005783endoplasmic reticulum
0.49EC:6 GO:0016874
0.73KEGG:R03876 GO:0004842
sp|Q8IYU4|UBQLN_HUMAN
Ubiquilin-like protein
Search
UBQLNL
0.97Ubiquilin like
0.79GO:1901340negative regulation of store-operated calcium channel activity
0.78GO:1903071positive regulation of ER-associated ubiquitin-dependent protein catabolic process
0.76GO:0035973aggrephagy
0.75GO:0034140negative regulation of toll-like receptor 3 signaling pathway
0.72GO:1902175regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.72GO:0097352autophagosome maturation
0.70GO:0030433ubiquitin-dependent ERAD pathway
0.70GO:0071456cellular response to hypoxia
0.68GO:0000045autophagosome assembly
0.68GO:0031398positive regulation of protein ubiquitination
0.71GO:0031593polyubiquitin modification-dependent protein binding
0.65GO:0019900kinase binding
0.62GO:0042802identical protein binding
0.50GO:0004984olfactory receptor activity
0.49GO:0004930G-protein coupled receptor activity
0.39GO:0019215intermediate filament binding
0.37GO:0019904protein domain specific binding
0.37GO:0005102receptor binding
0.36GO:0016746transferase activity, transferring acyl groups
0.72GO:0016235aggresome
0.70GO:0005776autophagosome
0.66GO:0048471perinuclear region of cytoplasm
0.60GO:0005783endoplasmic reticulum
0.59GO:0005829cytosol
0.58GO:0005654nucleoplasm
0.53GO:0005886plasma membrane
0.52GO:0043234protein complex
0.43GO:1905369endopeptidase complex
0.43GO:0031410cytoplasmic vesicle
0.36EC:2.3 GO:0016746
sp|Q8IYU8|MICU2_HUMAN
Calcium uptake protein 2, mitochondrial
Search
MICU2
0.95Mitochondrial calcium uptake 2
0.63GO:0051562negative regulation of mitochondrial calcium ion concentration
0.61GO:0006851mitochondrial calcium ion transmembrane transport
0.59GO:0051561positive regulation of mitochondrial calcium ion concentration
0.59GO:0070509calcium ion import
0.58GO:0060401cytosolic calcium ion transport
0.33GO:0007059chromosome segregation
0.33GO:0007229integrin-mediated signaling pathway
0.33GO:0010469regulation of receptor activity
0.69GO:0005509calcium ion binding
0.53GO:0046982protein heterodimerization activity
0.34GO:0019706protein-cysteine S-palmitoyltransferase activity
0.33GO:0008083growth factor activity
0.60GO:1990246uniplex complex
0.56GO:0005758mitochondrial intermembrane space
0.33GO:0000940condensed chromosome outer kinetochore
0.34EC:2.3.1.225 GO:0019706
sp|Q8IYV9|IZUM1_HUMAN
Izumo sperm-egg fusion protein 1
Search
IZUMO1
0.97Izumo sperm-egg fusion protein 1
0.85GO:0007342fusion of sperm to egg plasma membrane involved in single fertilization
0.85GO:0035036sperm-egg recognition
0.46GO:0034113heterotypic cell-cell adhesion
0.73GO:0005102receptor binding
0.47GO:0086080protein binding involved in heterotypic cell-cell adhesion
0.42GO:0042803protein homodimerization activity
0.41GO:0002080acrosomal membrane
0.37GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q8IYW2|CFA46_HUMAN
Cilia- and flagella-associated protein 46
Search
CFAP46
0.89Cilia- and flagella-associated protein 46
0.70GO:0060294cilium movement involved in cell motility
0.53GO:0035082axoneme assembly
0.75GO:0005929cilium
0.64GO:0032838plasma membrane bounded cell projection cytoplasm
0.56GO:0044430cytoskeletal part
sp|Q8IYW4|ENTD1_HUMAN
ENTH domain-containing protein 1
Search
ENTHD1
0.97ENTH domain-containing protein 1
0.75GO:1903671negative regulation of sprouting angiogenesis
0.68GO:0007565female pregnancy
0.66GO:0001701in utero embryonic development
0.65GO:0007219Notch signaling pathway
0.64GO:0048568embryonic organ development
0.51GO:0006897endocytosis
0.42GO:1905443regulation of clathrin coat assembly
0.40GO:0042059negative regulation of epidermal growth factor receptor signaling pathway
0.39GO:0031334positive regulation of protein complex assembly
0.37GO:0006397mRNA processing
0.43GO:0008289lipid binding
0.40GO:0035615clathrin adaptor activity
0.40GO:0044325ion channel binding
0.38GO:0008134transcription factor binding
0.35GO:0003723RNA binding
0.61GO:0005829cytosol
0.53GO:0030128clathrin coat of endocytic vesicle
0.45GO:0005905clathrin-coated pit
0.42GO:0098890extrinsic component of postsynaptic membrane
0.42GO:0098888extrinsic component of presynaptic membrane
0.41GO:0005634nucleus
0.40GO:0043195terminal bouton
0.39GO:0031234extrinsic component of cytoplasmic side of plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IYW5|RN168_HUMAN
E3 ubiquitin-protein ligase RNF168
Search
RNF168
0.96LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF168
0.80GO:0033522histone H2A ubiquitination
0.78GO:0045739positive regulation of DNA repair
0.75GO:0010212response to ionizing radiation
0.73GO:0006302double-strand break repair
0.64GO:0034244negative regulation of transcription elongation from RNA polymerase II promoter
0.63GO:0070534protein K63-linked ubiquitination
0.61GO:0010390histone monoubiquitination
0.55GO:0006511ubiquitin-dependent protein catabolic process
0.45GO:0002204somatic recombination of immunoglobulin genes involved in immune response
0.44GO:0002312B cell activation involved in immune response
0.74GO:0043130ubiquitin binding
0.73GO:0042393histone binding
0.71GO:0004842ubiquitin-protein transferase activity
0.70GO:0003682chromatin binding
0.63GO:0070530K63-linked polyubiquitin modification-dependent protein binding
0.53GO:0044877macromolecular complex binding
0.52GO:0016874ligase activity
0.51GO:0046872metal ion binding
0.69GO:0000151ubiquitin ligase complex
0.61GO:0035861site of double-strand break
0.57GO:0005634nucleus
0.51GO:0005829cytosol
0.50GO:0031974membrane-enclosed lumen
0.46GO:0043234protein complex
0.37GO:1990391DNA repair complex
0.30GO:0016020membrane
0.52EC:6 GO:0016874
0.71KEGG:R03876 GO:0004842
sp|Q8IYX0|ZN679_HUMAN
Zinc finger protein 679
Search
0.86Zinc finger protein 98
0.57GO:1903506regulation of nucleic acid-templated transcription
0.57GO:2000112regulation of cellular macromolecule biosynthetic process
0.56GO:0010468regulation of gene expression
0.38GO:0006351transcription, DNA-templated
0.37GO:0070895negative regulation of transposon integration
0.36GO:0021762substantia nigra development
0.34GO:1902679negative regulation of RNA biosynthetic process
0.53GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.36GO:0003700DNA binding transcription factor activity
0.30GO:0005515protein binding
0.45GO:0005622intracellular
0.38GO:0043227membrane-bounded organelle
sp|Q8IYX1|TBC21_HUMAN
TBC1 domain family member 21
Search
TBC1D21
0.97TBC1 domain family member 21 isoform A
0.66GO:0031338regulation of vesicle fusion
0.66GO:0090630activation of GTPase activity
0.56GO:0006886intracellular protein transport
0.49GO:1902017regulation of cilium assembly
0.44GO:0007283spermatogenesis
0.41GO:0030154cell differentiation
0.34GO:0055114oxidation-reduction process
0.71GO:0003779actin binding
0.65GO:0017137Rab GTPase binding
0.61GO:0005096GTPase activator activity
0.37GO:0016641oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.36GO:0005507copper ion binding
0.82GO:0001669acrosomal vesicle
0.47GO:0070062extracellular exosome
0.41GO:0005856cytoskeleton
0.37EC:1.4.3 GO:0016641
sp|Q8IYX3|CC116_HUMAN
Coiled-coil domain-containing protein 116
Search
CCDC116
0.97Coiled-coil domain-containing protein 116
0.41GO:0005515protein binding
0.77GO:0005813centrosome
0.40GO:0005737cytoplasm
0.30GO:0016020membrane
sp|Q8IYX4|DND1_HUMAN
Dead end protein homolog 1
Search
DND1
0.97DND microRNA-mediated repression inhibitor 1
0.62GO:0060965negative regulation of gene silencing by miRNA
0.59GO:0016554cytidine to uridine editing
0.57GO:0007281germ cell development
0.42GO:0002244hematopoietic progenitor cell differentiation
0.37GO:0006418tRNA aminoacylation for protein translation
0.34GO:2000742regulation of anterior head development
0.34GO:0008354germ cell migration
0.34GO:0048255mRNA stabilization
0.34GO:0060047heart contraction
0.33GO:2000145regulation of cell motility
0.61GO:0017091AU-rich element binding
0.41GO:0035198miRNA binding
0.37GO:0016875ligase activity, forming carbon-oxygen bonds
0.37GO:0140101catalytic activity, acting on a tRNA
0.36GO:0003729mRNA binding
0.35GO:0032559adenyl ribonucleotide binding
0.35GO:0005515protein binding
0.35GO:0008144drug binding
0.35GO:0035639purine ribonucleoside triphosphate binding
0.48GO:0005634nucleus
0.41GO:0005737cytoplasm
0.38GO:0019013viral nucleocapsid
0.36GO:0030529intracellular ribonucleoprotein complex
0.32GO:0043232intracellular non-membrane-bounded organelle
0.30GO:0016020membrane
0.37EC:6.1 GO:0016875
sp|Q8IYX7|SAXO1_HUMAN
Stabilizer of axonemal microtubules 1
Search
SAXO1
0.94Stabilizer of axonemal microtubules 1
0.60GO:0009631cold acclimation
0.60GO:0045724positive regulation of cilium assembly
0.57GO:0070417cellular response to cold
0.55GO:0050821protein stabilization
0.37GO:0030030cell projection organization
0.74GO:0008017microtubule binding
0.61GO:0005879axonemal microtubule
0.57GO:0036126sperm flagellum
0.56GO:0036064ciliary basal body
0.56GO:0005814centriole
sp|Q8IYX8|CE57L_HUMAN
Centrosomal protein CEP57L1
Search
CEP57L1
0.97Centrosomal protein 57 like 1
0.49GO:0034453microtubule anchoring
0.48GO:0000070mitotic sister chromatid segregation
0.35GO:0000060protein import into nucleus, translocation
0.33GO:0008543fibroblast growth factor receptor signaling pathway
0.33GO:0007286spermatid development
0.33GO:0051260protein homooligomerization
0.81GO:0043015gamma-tubulin binding
0.73GO:0042802identical protein binding
0.72GO:0008017microtubule binding
0.34GO:0017134fibroblast growth factor binding
0.33GO:0046983protein dimerization activity
0.47GO:0005813centrosome
0.37GO:0005874microtubule
0.33GO:0005737cytoplasm
0.32GO:0012505endomembrane system
0.32GO:0005634nucleus
sp|Q8IYY4|DZI1L_HUMAN
Zinc finger protein DZIP1L
Search
DZIP1L
0.96DAZ interacting zinc finger protein 1 like
0.63GO:0060271cilium assembly
0.56GO:0032880regulation of protein localization
0.39GO:0051220cytoplasmic sequestering of protein
0.38GO:0007224smoothened signaling pathway
0.35GO:0045184establishment of protein localization
0.34GO:0097359UDP-glucosylation
0.34GO:0010620negative regulation of transcription by transcription factor catabolism
0.34GO:0008589regulation of smoothened signaling pathway
0.33GO:0043413macromolecule glycosylation
0.33GO:0009101glycoprotein biosynthetic process
0.51GO:0003676nucleic acid binding
0.36GO:0046872metal ion binding
0.35GO:0005515protein binding
0.34GO:0003980UDP-glucose:glycoprotein glucosyltransferase activity
0.65GO:0036064ciliary basal body
0.61GO:0005814centriole
0.39GO:0097539ciliary transition fiber
0.36GO:0005654nucleoplasm
0.36GO:0005829cytosol
0.30GO:0016020membrane
0.34EC:2.4.1 GO:0003980
sp|Q8IZ02|LRC34_HUMAN
Leucine-rich repeat-containing protein 34
Search
LRRC34
0.93Leucine-rich repeat-containing protein 34
0.69GO:0030154cell differentiation
0.41GO:0006412translation
0.42GO:0003735structural constituent of ribosome
0.70GO:0005730nucleolus
0.49GO:0005737cytoplasm
0.41GO:1990904ribonucleoprotein complex
sp|Q8IZ07|AN13A_HUMAN
Ankyrin repeat domain-containing protein 13A
Search
ANKRD13A
0.95Ankyrin repeat domain-containing protein 13A
0.36GO:0035335peptidyl-tyrosine dephosphorylation
0.35GO:0006914autophagy
0.36GO:0008138protein tyrosine/serine/threonine phosphatase activity
0.36GO:0004725protein tyrosine phosphatase activity
0.53GO:0005886plasma membrane
0.43GO:0005770late endosome
0.30GO:0044425membrane part
0.36EC:3.1.3 GO:0008138
sp|Q8IZ08|GP135_HUMAN
Probable G-protein coupled receptor 135
Search
GPR135
0.97Leukocyte platelet-activating factor receptor
0.71GO:0007186G-protein coupled receptor signaling pathway
0.42GO:0001696gastric acid secretion
0.41GO:0007204positive regulation of cytosolic calcium ion concentration
0.41GO:0008284positive regulation of cell proliferation
0.40GO:0048565digestive tract development
0.40GO:0048732gland development
0.34GO:0045907positive regulation of vasoconstriction
0.33GO:0007610behavior
0.33GO:0090274positive regulation of somatostatin secretion
0.33GO:0001821histamine secretion
0.72GO:0004930G-protein coupled receptor activity
0.46GO:0001653peptide receptor activity
0.43GO:0031741type B gastrin/cholecystokinin receptor binding
0.38GO:0050346trans-L-3-hydroxyproline dehydratase activity
0.34GO:0030594neurotransmitter receptor activity
0.33GO:00469351-phosphatidylinositol-3-kinase regulator activity
0.33GO:0004435phosphatidylinositol phospholipase C activity
0.32GO:0005216ion channel activity
0.44GO:0005886plasma membrane
0.32GO:0005634nucleus
0.31GO:0005737cytoplasm
0.30GO:0016021integral component of membrane
0.38EC:4.2.1.77 GO:0050346
0.38KEGG:R04374 GO:0050346
sp|Q8IZ13|ZBED8_HUMAN
Protein ZBED8
Search
ZBED8
0.97Zinc finger BED-type containing 8
0.53GO:0006357regulation of transcription by RNA polymerase II
0.54GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.44GO:0003677DNA binding
0.41GO:0046983protein dimerization activity
0.68GO:0005654nucleoplasm
0.41GO:0005737cytoplasm
sp|Q8IZ16|CG061_HUMAN
Uncharacterized protein C7orf61
Search
sp|Q8IZ20|ZN683_HUMAN
Tissue-resident T-cell transcription regulator protein ZNF683
Search
ZNF683
0.52Tissue-resident T-cell transcription regulator protein ZNF683
0.56GO:0033082regulation of extrathymic T cell differentiation
0.54GO:0051136regulation of NK T cell differentiation
0.54GO:0032823regulation of natural killer cell differentiation
0.48GO:1990654sebum secreting cell proliferation
0.48GO:0000122negative regulation of transcription by RNA polymerase II
0.48GO:0048513animal organ development
0.47GO:0031665negative regulation of lipopolysaccharide-mediated signaling pathway
0.47GO:0060576intestinal epithelial cell development
0.47GO:0045579positive regulation of B cell differentiation
0.47GO:0030889negative regulation of B cell proliferation
0.52GO:1990841promoter-specific chromatin binding
0.51GO:0003676nucleic acid binding
0.46GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45GO:0042826histone deacetylase binding
0.38GO:0001191transcriptional repressor activity, RNA polymerase II transcription factor binding
0.34GO:0046872metal ion binding
0.32GO:0008168methyltransferase activity
0.40GO:0005634nucleus
0.36GO:0005737cytoplasm
0.32EC:2.1.1 GO:0008168
sp|Q8IZ21|PHAR4_HUMAN
Phosphatase and actin regulator 4
Search
PHACTR4
0.76Phosphatase and actin regulator
0.81GO:0032515negative regulation of phosphoprotein phosphatase activity
0.62GO:2001045negative regulation of integrin-mediated signaling pathway
0.61GO:0061386closure of optic fissure
0.59GO:0048484enteric nervous system development
0.58GO:0001755neural crest cell migration
0.58GO:0001843neural tube closure
0.57GO:0007266Rho protein signal transduction
0.52GO:0030036actin cytoskeleton organization
0.52GO:0051726regulation of cell cycle
0.51GO:0043085positive regulation of catalytic activity
0.84GO:0008157protein phosphatase 1 binding
0.81GO:0004864protein phosphatase inhibitor activity
0.73GO:0003779actin binding
0.60GO:0072542protein phosphatase activator activity
0.33GO:0005199structural constituent of cell wall
0.56GO:0030027lamellipodium
0.38GO:0005622intracellular
sp|Q8IZ26|ZNF34_HUMAN
Zinc finger protein 34
Search
ZNF34
0.65Zinc finger domain-containing protein (Fragment)
0.55GO:1903506regulation of nucleic acid-templated transcription
0.55GO:2000112regulation of cellular macromolecule biosynthetic process
0.54GO:0010468regulation of gene expression
0.37GO:0006351transcription, DNA-templated
0.36GO:0044789modulation by host of viral release from host cell
0.36GO:1902188positive regulation of viral release from host cell
0.36GO:0044794positive regulation by host of viral process
0.34GO:0043043peptide biosynthetic process
0.34GO:0044267cellular protein metabolic process
0.33GO:0007275multicellular organism development
0.51GO:0003676nucleic acid binding
0.51GO:0046872metal ion binding
0.45GO:0003700DNA binding transcription factor activity
0.35GO:0003735structural constituent of ribosome
0.33GO:0005515protein binding
0.43GO:0005622intracellular
0.42GO:0031974membrane-enclosed lumen
0.41GO:0043227membrane-bounded organelle
0.39GO:0044422organelle part
0.34GO:1990904ribonucleoprotein complex
0.34GO:0043228non-membrane-bounded organelle
sp|Q8IZ40|RCOR2_HUMAN
REST corepressor 2
Search
RCOR2
0.95REST corepressor 2
0.49GO:0045892negative regulation of transcription, DNA-templated
0.44GO:0006357regulation of transcription by RNA polymerase II
0.36GO:0006351transcription, DNA-templated
0.54GO:0003677DNA binding
0.54GO:0003714transcription corepressor activity
0.47GO:0019899enzyme binding
0.45GO:0001067regulatory region nucleic acid binding
0.44GO:0003700DNA binding transcription factor activity
0.44GO:0008134transcription factor binding
0.34GO:0001191transcriptional repressor activity, RNA polymerase II transcription factor binding
0.34GO:0001104RNA polymerase II transcription cofactor activity
0.61GO:0005634nucleus
0.51GO:0005667transcription factor complex
0.47GO:0017053transcriptional repressor complex
0.34GO:0000785chromatin
sp|Q8IZ41|RASEF_HUMAN
Ras and EF-hand domain-containing protein
Search
RASEF
0.89RAS and EF-hand domain containing
0.52GO:0051260protein homooligomerization
0.67GO:0003924GTPase activity
0.65GO:0032550purine ribonucleoside binding
0.65GO:0019001guanyl nucleotide binding
0.61GO:0005509calcium ion binding
0.53GO:0032555purine ribonucleotide binding
0.53GO:0035639purine ribonucleoside triphosphate binding
0.50GO:0042802identical protein binding
0.53GO:0048471perinuclear region of cytoplasm
0.47GO:0005829cytosol
sp|Q8IZ52|CHSS2_HUMAN
Chondroitin sulfate synthase 2
Search
CHPF
0.55Hexosyltransferase
0.54GO:0030206chondroitin sulfate biosynthetic process
0.85GO:0008376acetylgalactosaminyltransferase activity
0.32GO:0016887ATPase activity
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.81GO:0032580Golgi cisterna membrane
0.30GO:0031224intrinsic component of membrane
0.85EC:2.4.1 GO:0008376
sp|Q8IZ57|NRSN1_HUMAN
Neurensin-1
Search
NRSN1
0.97Vesicular membrane protein of 24 kDa
0.72GO:0007399nervous system development
0.33GO:0005515protein binding
0.77GO:0030133transport vesicle
0.57GO:0043025neuronal cell body
0.57GO:0030426growth cone
0.36GO:0005886plasma membrane
0.30GO:0044425membrane part
sp|Q8IZ63|PRR22_HUMAN
Proline-rich protein 22
Search
PRR22
0.97Proline-rich protein 22
sp|Q8IZ69|TRM2A_HUMAN
tRNA (uracil-5-)-methyltransferase homolog A
Search
TRMT2A
0.95tRNA (Uracil-5-)-methyltransferase like protein A
0.67GO:0001510RNA methylation
0.61GO:0006396RNA processing
0.67GO:0008173RNA methyltransferase activity
0.55GO:0003723RNA binding
0.33GO:0008757S-adenosylmethionine-dependent methyltransferase activity
0.33GO:0140101catalytic activity, acting on a tRNA
0.30GO:0031224intrinsic component of membrane
0.67EC:2.1.1 GO:0008173
sp|Q8IZ73|RUSD2_HUMAN
RNA pseudouridylate synthase domain-containing protein 2
Search
RPUSD2
0.94RNA pseudouridylate synthase domain-containing protein 2
0.72GO:0001522pseudouridine synthesis
0.50GO:0000154rRNA modification
0.34GO:0008213protein alkylation
0.34GO:0043414macromolecule methylation
0.72GO:0009982pseudouridine synthase activity
0.59GO:0003723RNA binding
0.50GO:0019239deaminase activity
0.35GO:0004719protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
0.72EC:5.4.99.12 GO:0009982
sp|Q8IZ81|ELMD2_HUMAN
ELMO domain-containing protein 2
Search
ELMOD2
0.96ELMO domain-containing protein 2
0.75GO:0043547positive regulation of GTPase activity
0.56GO:0050688regulation of defense response to virus
0.35GO:0051607defense response to virus
0.35GO:1903955positive regulation of protein targeting to mitochondrion
0.34GO:0031647regulation of protein stability
0.33GO:0090175regulation of establishment of planar polarity
0.33GO:0000281mitotic cytokinesis
0.76GO:0005096GTPase activator activity
0.33GO:0005654nucleoplasm
0.33GO:0005829cytosol
0.33GO:0043234protein complex
0.30GO:0016020membrane
sp|Q8IZ83|A16A1_HUMAN
Aldehyde dehydrogenase family 16 member A1
Search
ALDH16A1
0.39NAD-dependent aldehyde dehydrogenase
0.52GO:0055114oxidation-reduction process
0.38GO:0010469regulation of receptor activity
0.36GO:0009450gamma-aminobutyric acid catabolic process
0.35GO:0043043peptide biosynthetic process
0.34GO:0044267cellular protein metabolic process
0.34GO:0010467gene expression
0.34GO:0009059macromolecule biosynthetic process
0.32GO:0055085transmembrane transport
0.73GO:0004029aldehyde dehydrogenase (NAD) activity
0.39GO:0005125cytokine activity
0.37GO:0009013succinate-semialdehyde dehydrogenase [NAD(P)+] activity
0.35GO:0003735structural constituent of ribosome
0.33GO:0015293symporter activity
0.38GO:0070062extracellular exosome
0.36GO:0015934large ribosomal subunit
0.30GO:0031224intrinsic component of membrane
0.73EC:1.2.1.3 GO:0004029
sp|Q8IZ96|CKLF1_HUMAN
CKLF-like MARVEL transmembrane domain-containing protein 1
Search
CMTM1
0.81CKLF like MARVEL transmembrane domain containing 1
0.47GO:0010469regulation of receptor activity
0.45GO:0006935chemotaxis
0.49GO:0005125cytokine activity
0.46GO:0005615extracellular space
0.30GO:0044425membrane part
sp|Q8IZA0|K319L_HUMAN
Dyslexia-associated protein KIAA0319-like protein
Search
KIAA0319L
0.96Dyslexia susceptibility 2-like
0.38GO:2000171negative regulation of dendrite development
0.37GO:0001764neuron migration
0.30GO:0005515protein binding
0.44GO:0031410cytoplasmic vesicle
0.39GO:0070062extracellular exosome
0.38GO:0012505endomembrane system
0.37GO:0098588bounding membrane of organelle
0.37GO:0031984organelle subcompartment
0.36GO:0043231intracellular membrane-bounded organelle
0.36GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IZA3|H1FOO_HUMAN
Histone H1oo
Search
H1FOO
0.97Oocyte-specific H1 histone
0.79GO:0006334nucleosome assembly
0.67GO:2000737negative regulation of stem cell differentiation
0.67GO:0044030regulation of DNA methylation
0.66GO:0016584nucleosome positioning
0.66GO:0031492nucleosomal DNA binding
0.35GO:0046982protein heterodimerization activity
0.75GO:0000786nucleosome
0.61GO:0005634nucleus
0.54GO:0031974membrane-enclosed lumen
0.38GO:0070062extracellular exosome
sp|Q8IZC4|RTKN2_HUMAN
Rhotekin-2
Search
RTKN2
0.97Rhotekin-2
0.74GO:0030097hemopoiesis
0.58GO:0007165signal transduction
0.56GO:0032185septin cytoskeleton organization
0.36GO:0008284positive regulation of cell proliferation
0.35GO:0034260negative regulation of GTPase activity
0.34GO:0042981regulation of apoptotic process
0.33GO:0006915apoptotic process
0.57GO:0017049GTP-Rho binding
0.35GO:0005095GTPase inhibitor activity
0.32GO:0032550purine ribonucleoside binding
0.32GO:0019001guanyl nucleotide binding
0.32GO:0032555purine ribonucleotide binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.37GO:0005622intracellular
0.34GO:0005886plasma membrane
sp|Q8IZC6|CORA1_HUMAN
Collagen alpha-1(XXVII) chain
Search
COL27A1
0.82Collagen type XXVII alpha 1 chain
0.63GO:0003431growth plate cartilage chondrocyte development
0.57GO:0030198extracellular matrix organization
0.40GO:0002244hematopoietic progenitor cell differentiation
0.37GO:0048570notochord morphogenesis
0.37GO:0030282bone mineralization
0.79GO:0005201extracellular matrix structural constituent
0.35GO:0046872metal ion binding
0.73GO:0005581collagen trimer
0.62GO:0098643banded collagen fibril
0.35GO:0005788endoplasmic reticulum lumen
0.30GO:0031224intrinsic component of membrane
sp|Q8IZC7|ZN101_HUMAN
Zinc finger protein 101
Search
0.81Zinc finger protein 14
0.56GO:2001141regulation of RNA biosynthetic process
0.56GO:2000112regulation of cellular macromolecule biosynthetic process
0.55GO:0010468regulation of gene expression
0.39GO:0006351transcription, DNA-templated
0.36GO:0014022neural plate elongation
0.35GO:0060029convergent extension involved in organogenesis
0.35GO:0060028convergent extension involved in axis elongation
0.35GO:0060669embryonic placenta morphogenesis
0.35GO:0060027convergent extension involved in gastrulation
0.34GO:0051253negative regulation of RNA metabolic process
0.52GO:0046872metal ion binding
0.51GO:0003676nucleic acid binding
0.38GO:0005515protein binding
0.33GO:0003700DNA binding transcription factor activity
0.44GO:0005622intracellular
0.38GO:0043227membrane-bounded organelle
sp|Q8IZD0|SAM14_HUMAN
Sterile alpha motif domain-containing protein 14
Search
SAMD14
0.97Sterile alpha motif domain-containing protein 14
0.67GO:0050804modulation of chemical synaptic transmission
0.63GO:0042127regulation of cell proliferation
0.55GO:0019722calcium-mediated signaling
0.51GO:0007015actin filament organization
0.37GO:0006265DNA topological change
0.35GO:0006508proteolysis
0.70GO:0008157protein phosphatase 1 binding
0.61GO:0003779actin binding
0.38GO:0061505DNA topoisomerase II activity
0.37GO:0008094DNA-dependent ATPase activity
0.37GO:0004252serine-type endopeptidase activity
0.34GO:0032559adenyl ribonucleotide binding
0.34GO:0003677DNA binding
0.34GO:0008144drug binding
0.34GO:0035639purine ribonucleoside triphosphate binding
0.56GO:0043197dendritic spine
0.56GO:0030175filopodium
0.54GO:0030864cortical actin cytoskeleton
0.30GO:0016020membrane
0.37EC:3.4.21 GO:0004252
sp|Q8IZD2|KMT2E_HUMAN
Histone-lysine N-methyltransferase 2E
Search
KMT2E
0.73Histone-lysine N-methyltransferase MLL5
0.58GO:1905437positive regulation of histone H3-K4 trimethylation
0.55GO:0002446neutrophil mediated immunity
0.54GO:0042119neutrophil activation
0.54GO:1900087positive regulation of G1/S transition of mitotic cell cycle
0.53GO:0030218erythrocyte differentiation
0.52GO:0032259methylation
0.49GO:0006305DNA alkylation
0.49GO:0044728DNA methylation or demethylation
0.48GO:0045893positive regulation of transcription, DNA-templated
0.35GO:0045010actin nucleation
0.53GO:0035064methylated histone binding
0.53GO:0046872metal ion binding
0.47GO:0019899enzyme binding
0.47GO:0008168methyltransferase activity
0.36GO:0052795exo-alpha-(2->6)-sialidase activity
0.36GO:0052796exo-alpha-(2->8)-sialidase activity
0.36GO:0052794exo-alpha-(2->3)-sialidase activity
0.35GO:0008017microtubule binding
0.32GO:0140096catalytic activity, acting on a protein
0.32GO:0003713transcription coactivator activity
0.53GO:0035327transcriptionally active chromatin
0.43GO:0005634nucleus
0.43GO:0043234protein complex
0.35GO:0005884actin filament
0.32GO:0070013intracellular organelle lumen
0.31GO:0005886plasma membrane
0.31GO:0005737cytoplasm
0.47EC:2.1.1 GO:0008168
sp|Q8IZD4|DCP1B_HUMAN
mRNA-decapping enzyme 1B
Search
DCP1B
0.84DCP1 decapping enzyme homolog B
0.84GO:0000290deadenylation-dependent decapping of nuclear-transcribed mRNA
0.73GO:0043085positive regulation of catalytic activity
0.54GO:0031087deadenylation-independent decapping of nuclear-transcribed mRNA
0.75GO:0008047enzyme activator activity
0.49GO:0003729mRNA binding
0.57GO:0005829cytosol
0.51GO:0000932P-body
0.48GO:0043231intracellular membrane-bounded organelle
0.30GO:0016020membrane
sp|Q8IZD6|S22AF_HUMAN
Solute carrier family 22 member 15
Search
SLC22A15
0.97Solute carrier family 22 (Organic cation transporter), member 15
0.54GO:0055085transmembrane transport
0.43GO:0015711organic anion transport
0.56GO:0022857transmembrane transporter activity
0.30GO:0044425membrane part
sp|Q8IZD9|DOCK3_HUMAN
Dedicator of cytokinesis protein 3
Search
DOCK3
0.95Dedicator of cytokinesis protein 3
0.76GO:0007264small GTPase mediated signal transduction
0.65GO:0065009regulation of molecular function
0.75GO:0005085guanyl-nucleotide exchange factor activity
0.37GO:0017124SH3 domain binding
0.45GO:0005829cytosol
sp|Q8IZE3|PACE1_HUMAN
Protein-associating with the carboxyl-terminal domain of ezrin
Search
SCYL3
0.92Protein-associating with the carboxyl-terminal domain of ezrin
0.63GO:0006468protein phosphorylation
0.38GO:0016477cell migration
0.63GO:0004672protein kinase activity
0.55GO:0030554adenyl nucleotide binding
0.54GO:0097367carbohydrate derivative binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.37GO:0019894kinesin binding
0.44GO:0030027lamellipodium
0.41GO:0005794Golgi apparatus
0.36GO:0005871kinesin complex
0.30GO:0044425membrane part
sp|Q8IZF0|NALCN_HUMAN
Sodium leak channel non-selective protein
Search
NALCN
0.94Brain voltage-gated cation channel
0.61GO:0098655cation transmembrane transport
0.50GO:0086010membrane depolarization during action potential
0.46GO:0006816calcium ion transport
0.40GO:0060075regulation of resting membrane potential
0.38GO:0034765regulation of ion transmembrane transport
0.37GO:0071804cellular potassium ion transport
0.37GO:0006814sodium ion transport
0.35GO:0098660inorganic ion transmembrane transport
0.34GO:0030866cortical actin cytoskeleton organization
0.74GO:0005261cation channel activity
0.39GO:0022842narrow pore channel activity
0.37GO:0022832voltage-gated channel activity
0.37GO:0015081sodium ion transmembrane transporter activity
0.37GO:0022839ion gated channel activity
0.37GO:0008381mechanosensitive ion channel activity
0.35GO:0005515protein binding
0.33GO:0005198structural molecule activity
0.39GO:0005886plasma membrane
0.33GO:0005856cytoskeleton
0.30GO:0016021integral component of membrane
sp|Q8IZF2|AGRF5_HUMAN
Adhesion G protein-coupled receptor F5
Search
ADGRF5
0.86Adhesion G protein-coupled receptor F5
0.71GO:0007166cell surface receptor signaling pathway
0.71GO:0007186G-protein coupled receptor signaling pathway
0.60GO:0043129surfactant homeostasis
0.59GO:0043031negative regulation of macrophage activation
0.58GO:0071073positive regulation of phospholipid biosynthetic process
0.57GO:0045444fat cell differentiation
0.55GO:0042593glucose homeostasis
0.52GO:0006112energy reserve metabolic process
0.35GO:0032793positive regulation of CREB transcription factor activity
0.35GO:0007416synapse assembly
0.72GO:0004930G-protein coupled receptor activity
0.33GO:0009881photoreceptor activity
0.55GO:0045177apical part of cell
0.52GO:0009986cell surface
0.51GO:0031410cytoplasmic vesicle
0.36GO:0005886plasma membrane
0.32GO:0005576extracellular region
0.30GO:0016021integral component of membrane
sp|Q8IZF3|AGRF4_HUMAN
Adhesion G protein-coupled receptor F4
Search
0.97Adhesion G protein-coupled receptor F4
0.71GO:0007166cell surface receptor signaling pathway
0.71GO:0007186G-protein coupled receptor signaling pathway
0.45GO:0032793positive regulation of CREB transcription factor activity
0.44GO:0007416synapse assembly
0.44GO:0007613memory
0.44GO:0019933cAMP-mediated signaling
0.42GO:0031175neuron projection development
0.36GO:0043129surfactant homeostasis
0.36GO:0043031negative regulation of macrophage activation
0.36GO:0071073positive regulation of phospholipid biosynthetic process
0.72GO:0004930G-protein coupled receptor activity
0.32GO:0005509calcium ion binding
0.32GO:0005515protein binding
0.32GO:0009881photoreceptor activity
0.37GO:0005886plasma membrane
0.35GO:0045177apical part of cell
0.35GO:0009986cell surface
0.34GO:0031410cytoplasmic vesicle
0.33GO:0005576extracellular region
0.30GO:0016021integral component of membrane
sp|Q8IZF4|AGRG5_HUMAN
Adhesion G-protein coupled receptor G5
Search
ADGRG5
0.96Adhesion G-protein coupled receptor G5
0.71GO:0007166cell surface receptor signaling pathway
0.71GO:0007186G-protein coupled receptor signaling pathway
0.51GO:0010573vascular endothelial growth factor production
0.50GO:2001223negative regulation of neuron migration
0.50GO:0021819layer formation in cerebral cortex
0.50GO:0070528protein kinase C signaling
0.50GO:0021796cerebral cortex regionalization
0.49GO:0035025positive regulation of Rho protein signal transduction
0.49GO:0072520seminiferous tubule development
0.48GO:2000179positive regulation of neural precursor cell proliferation
0.72GO:0004930G-protein coupled receptor activity
0.48GO:0050840extracellular matrix binding
0.48GO:0005518collagen binding
0.48GO:0008201heparin binding
0.34GO:0030246carbohydrate binding
0.32GO:0004672protein kinase activity
0.32GO:0032559adenyl ribonucleotide binding
0.32GO:0008144drug binding
0.32GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0097451glial limiting end-foot
0.38GO:0045121membrane raft
0.36GO:0005576extracellular region
0.36GO:0005886plasma membrane
0.35GO:0005622intracellular
0.34GO:0031982vesicle
0.30GO:0016021integral component of membrane
sp|Q8IZF5|AGRF3_HUMAN
Adhesion G-protein coupled receptor F3
Search
ADGRF3
0.97Adhesion G-protein coupled receptor F3
0.71GO:0007166cell surface receptor signaling pathway
0.71GO:0007186G-protein coupled receptor signaling pathway
0.35GO:0006631fatty acid metabolic process
0.35GO:0032793positive regulation of CREB transcription factor activity
0.35GO:0007416synapse assembly
0.35GO:0007613memory
0.35GO:0019933cAMP-mediated signaling
0.34GO:0031175neuron projection development
0.33GO:0055114oxidation-reduction process
0.31GO:0006950response to stress
0.72GO:0004930G-protein coupled receptor activity
0.36GO:00038573-hydroxyacyl-CoA dehydrogenase activity
0.32GO:0005886plasma membrane
0.32GO:0005622intracellular
0.30GO:0016021integral component of membrane
0.36EC:1.1.1.35 GO:0003857
sp|Q8IZF6|AGRG4_HUMAN
Adhesion G-protein coupled receptor G4
Search
ADGRG4
0.86LOW QUALITY PROTEIN: adhesion G-protein coupled receptor G4
0.71GO:0007166cell surface receptor signaling pathway
0.71GO:0007186G-protein coupled receptor signaling pathway
0.34GO:0005977glycogen metabolic process
0.34GO:0007283spermatogenesis
0.33GO:0016310phosphorylation
0.72GO:0004930G-protein coupled receptor activity
0.34GO:0005516calmodulin binding
0.33GO:0016301kinase activity
0.45GO:0005829cytosol
0.40GO:0005886plasma membrane
0.38GO:0045177apical part of cell
0.36GO:0070062extracellular exosome
0.35GO:0009986cell surface
0.30GO:0016021integral component of membrane
sp|Q8IZF7|AGRF2_HUMAN
Adhesion G-protein coupled receptor F2
Search
ADGRF2
0.97Adhesion G-protein coupled receptor F2
0.71GO:0007166cell surface receptor signaling pathway
0.71GO:0007186G-protein coupled receptor signaling pathway
0.52GO:0043129surfactant homeostasis
0.51GO:0043031negative regulation of macrophage activation
0.51GO:0071073positive regulation of phospholipid biosynthetic process
0.50GO:0045444fat cell differentiation
0.48GO:0042593glucose homeostasis
0.46GO:0006112energy reserve metabolic process
0.72GO:0004930G-protein coupled receptor activity
0.48GO:0045177apical part of cell
0.46GO:0009986cell surface
0.45GO:0031410cytoplasmic vesicle
0.34GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IZH2|XRN1_HUMAN
5'-3' exoribonuclease 1
Search
XRN1
0.795'-3' exoribonuclease 1
0.75GO:0000956nuclear-transcribed mRNA catabolic process
0.62GO:0090305nucleic acid phosphodiester bond hydrolysis
0.61GO:0008334histone mRNA metabolic process
0.59GO:0071027nuclear RNA surveillance
0.55GO:0016075rRNA catabolic process
0.41GO:1905795cellular response to puromycin
0.40GO:0071409cellular response to cycloheximide
0.40GO:0033574response to testosterone
0.38GO:0017148negative regulation of translation
0.36GO:0032211negative regulation of telomere maintenance via telomerase
0.74GO:00084095'-3' exonuclease activity
0.54GO:0016896exoribonuclease activity, producing 5'-phosphomonoesters
0.52GO:0003723RNA binding
0.40GO:0051880G-quadruplex DNA binding
0.34GO:0005515protein binding
0.32GO:0016773phosphotransferase activity, alcohol group as acceptor
0.50GO:0005829cytosol
0.47GO:0005634nucleus
0.44GO:0005886plasma membrane
0.40GO:0000932P-body
0.38GO:0043025neuronal cell body
0.38GO:0030425dendrite
0.38GO:0045202synapse
0.30GO:0016021integral component of membrane
0.54EC:3.1.13 GO:0016896
sp|Q8IZI9|IFNL3_HUMAN
Interferon lambda-3
Search
0.97Interferon lambda
0.85GO:0007259JAK-STAT cascade
0.79GO:0050778positive regulation of immune response
0.78GO:0051607defense response to virus
0.76GO:0010469regulation of receptor activity
0.57GO:0050863regulation of T cell activation
0.54GO:0045087innate immune response
0.52GO:0045345positive regulation of MHC class I biosynthetic process
0.52GO:0032696negative regulation of interleukin-13 production
0.51GO:0032714negative regulation of interleukin-5 production
0.51GO:0002829negative regulation of type 2 immune response
0.81GO:0005125cytokine activity
0.53GO:0032003interleukin-28 receptor binding
0.52GO:0032002interleukin-28 receptor complex
0.52GO:0005615extracellular space
0.45GO:0005622intracellular
sp|Q8IZJ0|IFNL2_HUMAN
Interferon lambda-2
Search
0.97Interferon lambda
0.85GO:0007259JAK-STAT cascade
0.79GO:0050778positive regulation of immune response
0.78GO:0051607defense response to virus
0.76GO:0010469regulation of receptor activity
0.57GO:0050863regulation of T cell activation
0.55GO:0045087innate immune response
0.52GO:0045345positive regulation of MHC class I biosynthetic process
0.52GO:0032696negative regulation of interleukin-13 production
0.52GO:0032714negative regulation of interleukin-5 production
0.51GO:0002829negative regulation of type 2 immune response
0.81GO:0005125cytokine activity
0.53GO:0032003interleukin-28 receptor binding
0.52GO:0032002interleukin-28 receptor complex
0.52GO:0005615extracellular space
0.45GO:0005622intracellular
sp|Q8IZJ1|UNC5B_HUMAN
Netrin receptor UNC5B
Search
UNC5B
0.97Unc-5 netrin receptor B
0.85GO:0038007netrin-activated signaling pathway
0.59GO:0033564anterior/posterior axon guidance
0.56GO:1901099negative regulation of signal transduction in absence of ligand
0.55GO:2001239regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.55GO:0014068positive regulation of phosphatidylinositol 3-kinase signaling
0.54GO:2001237negative regulation of extrinsic apoptotic signaling pathway
0.54GO:0043524negative regulation of neuron apoptotic process
0.45GO:0001569branching involved in blood vessel morphogenesis
0.44GO:0016525negative regulation of angiogenesis
0.41GO:0043065positive regulation of apoptotic process
0.85GO:0005042netrin receptor activity
0.37GO:0005515protein binding
0.34GO:0005337nucleoside transmembrane transporter activity
0.38GO:0045121membrane raft
0.37GO:0005886plasma membrane
0.34GO:0005829cytosol
0.30GO:0016021integral component of membrane
sp|Q8IZJ3|CPMD8_HUMAN
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8
Search
CPAMD8
0.95C3 and PZP like, alpha-2-macroglobulin domain containing 8
0.74GO:0010951negative regulation of endopeptidase activity
0.53GO:0001654eye development
0.75GO:0004866endopeptidase inhibitor activity
0.72GO:0005615extracellular space
0.33GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IZJ4|RGDSR_HUMAN
Ral-GDS-related protein
Search
RGL4
0.97Ral guanine nucleotide dissociation stimulator like 4
0.77GO:0007264small GTPase mediated signal transduction
0.66GO:0065009regulation of molecular function
0.34GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process
0.33GO:0006289nucleotide-excision repair
0.33GO:0055114oxidation-reduction process
0.32GO:0007166cell surface receptor signaling pathway
0.32GO:0007186G-protein coupled receptor signaling pathway
0.75GO:0005085guanyl-nucleotide exchange factor activity
0.43GO:0030695GTPase regulator activity
0.35GO:0017160Ral GTPase binding
0.33GO:0003684damaged DNA binding
0.33GO:0016491oxidoreductase activity
0.32GO:0004930G-protein coupled receptor activity
0.46GO:0005903brush border
0.45GO:0005622intracellular
0.38GO:0043227membrane-bounded organelle
0.30GO:0016020membrane
0.33EC:1 GO:0016491
sp|Q8IZJ6|TDH_HUMAN
Inactive L-threonine 3-dehydrogenase, mitochondrial
Search
TDH
0.54L-threonine dehydrogenase
0.49GO:0006567threonine catabolic process
0.39GO:0055114oxidation-reduction process
0.37GO:0006544glycine metabolic process
0.37GO:0042737drug catabolic process
0.60GO:0050662coenzyme binding
0.51GO:0008743L-threonine 3-dehydrogenase activity
0.47GO:0042802identical protein binding
0.42GO:0005739mitochondrion
0.33GO:0019866organelle inner membrane
0.30GO:0044425membrane part
0.51EC:1.1.1.103 GO:0008743
0.51KEGG:R01465 GO:0008743
sp|Q8IZK6|MCLN2_HUMAN
Mucolipin-2
Search
MCOLN2
0.89Mucolipin-2 isoform B
0.59GO:0071642positive regulation of macrophage inflammatory protein 1 alpha production
0.59GO:0035926chemokine (C-C motif) ligand 2 secretion
0.58GO:0071651positive regulation of chemokine (C-C motif) ligand 5 production
0.58GO:2000343positive regulation of chemokine (C-X-C motif) ligand 2 production
0.58GO:0071639positive regulation of monocyte chemotactic protein-1 production
0.57GO:1905517macrophage migration
0.55GO:1990266neutrophil migration
0.50GO:0042491inner ear auditory receptor cell differentiation
0.49GO:0051259protein oligomerization
0.48GO:0007626locomotory behavior
0.37GO:0005262calcium channel activity
0.35GO:0097682intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity
0.34GO:0008289lipid binding
0.32GO:0043168anion binding
0.54GO:0055037recycling endosome
0.39GO:0005886plasma membrane
0.38GO:0005765lysosomal membrane
0.38GO:0010008endosome membrane
0.37GO:0005770late endosome
0.36GO:0000421autophagosome membrane
0.35GO:0005769early endosome
0.34GO:0031166integral component of vacuolar membrane
0.34GO:0032420stereocilium
0.34GO:0031252cell leading edge
sp|Q8IZL2|MAML2_HUMAN
Mastermind-like protein 2
Search
MAML2
0.93Mastermind like transcriptional coactivator 2
0.81GO:0007219Notch signaling pathway
0.75GO:0045944positive regulation of transcription by RNA polymerase II
0.44GO:0045747positive regulation of Notch signaling pathway
0.42GO:0006367transcription initiation from RNA polymerase II promoter
0.79GO:0003713transcription coactivator activity
0.68GO:0016607nuclear speck
0.30GO:0031224intrinsic component of membrane
sp|Q8IZL8|PELP1_HUMAN
Proline-, glutamic acid- and leucine-rich protein 1
Search
PELP1
0.91Proline, glutamate and leucine rich protein 1
0.86GO:0071391cellular response to estrogen stimulus
0.63GO:0005730nucleolus
sp|Q8IZL9|CDK20_HUMAN
Cyclin-dependent kinase 20
Search
CDK20
0.96Cell division protein kinase 20
0.63GO:0006468protein phosphorylation
0.50GO:1904031positive regulation of cyclin-dependent protein kinase activity
0.42GO:0060271cilium assembly
0.38GO:0051301cell division
0.38GO:0007275multicellular organism development
0.38GO:0007049cell cycle
0.34GO:0035335peptidyl-tyrosine dephosphorylation
0.69GO:0008353RNA polymerase II carboxy-terminal domain kinase activity
0.55GO:0032559adenyl ribonucleotide binding
0.54GO:0008144drug binding
0.54GO:0035639purine ribonucleoside triphosphate binding
0.52GO:0019912cyclin-dependent protein kinase activating kinase activity
0.51GO:0004693cyclin-dependent protein serine/threonine kinase activity
0.34GO:0005515protein binding
0.34GO:0004725protein tyrosine phosphatase activity
0.69GO:0070985TFIIK complex
0.40GO:0005929cilium
0.37GO:0005737cytoplasm
0.30GO:0031224intrinsic component of membrane
0.69EC:2.7.11.23 GO:0008353
sp|Q8IZM0|CNG1O_HUMAN
Putative CNGA1-overlapping antisense gene protein
Search
0.44Putative CNGA1-overlapping antisense gene protein
sp|Q8IZM8|ZN654_HUMAN
Zinc finger protein 654
Search
ZNF654
0.76Zinc finger protein 654
0.36GO:0097659nucleic acid-templated transcription
0.36GO:1903506regulation of nucleic acid-templated transcription
0.36GO:2000112regulation of cellular macromolecule biosynthetic process
0.35GO:0010468regulation of gene expression
0.35GO:0010467gene expression
0.35GO:0034645cellular macromolecule biosynthetic process
0.51GO:0003676nucleic acid binding
0.35GO:0046872metal ion binding
0.36GO:0005634nucleus
sp|Q8IZM9|S38A6_HUMAN
Probable sodium-coupled neutral amino acid transporter 6
Search
SLC38A6
0.93Probable sodium-coupled neutral amino acid transporter 6
0.45GO:0003333amino acid transmembrane transport
0.37GO:0006814sodium ion transport
0.45GO:0015171amino acid transmembrane transporter activity
0.43GO:0005886plasma membrane
0.30GO:0016021integral component of membrane
sp|Q8IZN3|ZDH14_HUMAN
Probable palmitoyltransferase ZDHHC14
Search
ZDHHC14
0.57Palmitoyltransferase
0.55GO:0018345protein palmitoylation
0.34GO:0000281mitotic cytokinesis
0.33GO:0006338chromatin remodeling
0.33GO:0006897endocytosis
0.33GO:0006886intracellular protein transport
0.78GO:0019706protein-cysteine S-palmitoyltransferase activity
0.33GO:0035091phosphatidylinositol binding
0.32GO:0003677DNA binding
0.48GO:0005783endoplasmic reticulum
0.34GO:0071565nBAF complex
0.34GO:0016514SWI/SNF complex
0.30GO:0016020membrane
0.78EC:2.3.1.225 GO:0019706
sp|Q8IZN7|D107A_HUMAN
Beta-defensin 107
Search
0.63Beta-defensin
0.79GO:0045087innate immune response
0.78GO:0042742defense response to bacterium
0.40GO:0008289lipid binding
0.66GO:0005576extracellular region
0.49GO:0009986cell surface
sp|Q8IZP0|ABI1_HUMAN
Abl interactor 1
Search
ABI1
0.86Abl interactor 1
0.85GO:0061098positive regulation of protein tyrosine kinase activity
0.81GO:0008154actin polymerization or depolymerization
0.63GO:0072673lamellipodium morphogenesis
0.62GO:0035855megakaryocyte development
0.60GO:0001756somitogenesis
0.60GO:0048813dendrite morphogenesis
0.57GO:0018108peptidyl-tyrosine phosphorylation
0.40GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis
0.39GO:0048010vascular endothelial growth factor receptor signaling pathway
0.38GO:0008285negative regulation of cell proliferation
0.86GO:0030296protein tyrosine kinase activator activity
0.60GO:0045296cadherin binding
0.59GO:0017124SH3 domain binding
0.56GO:0032403protein complex binding
0.37GO:0008092cytoskeletal protein binding
0.35GO:0031492nucleosomal DNA binding
0.34GO:0008134transcription factor binding
0.33GO:0003735structural constituent of ribosome
0.64GO:0032433filopodium tip
0.64GO:0031209SCAR complex
0.61GO:0030027lamellipodium
0.56GO:0043005neuron projection
0.40GO:0014069postsynaptic density
0.39GO:0070062extracellular exosome
0.39GO:0030427site of polarized growth
0.39GO:0045211postsynaptic membrane
0.38GO:0030054cell junction
0.37GO:0005856cytoskeleton
sp|Q8IZP1|TBC3A_HUMAN
TBC1 domain family member 3
Search
0.97TBC1 domain family member 3
0.85GO:0031338regulation of vesicle fusion
0.84GO:0090630activation of GTPase activity
0.69GO:0006886intracellular protein transport
0.47GO:1902017regulation of cilium assembly
0.81GO:0017137Rab GTPase binding
0.76GO:0005096GTPase activator activity
0.67GO:0012505endomembrane system
0.54GO:0005886plasma membrane
0.45GO:0005622intracellular
0.42GO:0031982vesicle
0.42GO:0098805whole membrane
0.42GO:0098588bounding membrane of organelle
sp|Q8IZP2|ST134_HUMAN
Putative protein FAM10A4
Search
0.97Testis secretory sperm-binding protein Li 233m
0.41GO:0061084negative regulation of protein refolding
0.39GO:0051289protein homotetramerization
0.39GO:0051085chaperone cofactor-dependent protein refolding
0.33GO:0006351transcription, DNA-templated
0.63GO:0046983protein dimerization activity
0.41GO:0032564dATP binding
0.40GO:0030544Hsp70 protein binding
0.38GO:0051087chaperone binding
0.38GO:0019904protein domain specific binding
0.38GO:0032403protein complex binding
0.37GO:0042802identical protein binding
0.37GO:0051082unfolded protein binding
0.35GO:0030674protein binding, bridging
0.44GO:0005829cytosol
0.38GO:0070062extracellular exosome
0.35GO:0043234protein complex
0.33GO:0005634nucleus
sp|Q8IZP6|R113B_HUMAN
RING finger protein 113B
Search
RNF113A
0.65Zinc finger protein 183
0.52GO:0034247snoRNA splicing
0.49GO:0045292mRNA cis splicing, via spliceosome
0.54GO:0046872metal ion binding
0.33GO:0005515protein binding
0.33GO:0016874ligase activity
0.49GO:0005684U2-type spliceosomal complex
0.33EC:6 GO:0016874
sp|Q8IZP7|H6ST3_HUMAN
Heparan-sulfate 6-O-sulfotransferase 3
Search
0.76Heparan-sulfate 6-O-sulfotransferase
0.60GO:0015015heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.46GO:0048666neuron development
0.45GO:0048286lung alveolus development
0.44GO:0001525angiogenesis
0.43GO:0060716labyrinthine layer blood vessel development
0.34GO:0060173limb development
0.33GO:0006024glycosaminoglycan biosynthetic process
0.78GO:0008146sulfotransferase activity
0.35GO:00506563'-phosphoadenosine 5'-phosphosulfate binding
0.35GO:0070492oligosaccharide binding
0.34GO:0000139Golgi membrane
0.33GO:0005887integral component of plasma membrane
0.78EC:2.8.2 GO:0008146
sp|Q8IZP9|AGRG2_HUMAN
Adhesion G-protein coupled receptor G2
Search
ADGRG2
0.96Epididymis-specific protein 6
0.71GO:0007166cell surface receptor signaling pathway
0.71GO:0007186G-protein coupled receptor signaling pathway
0.35GO:0007283spermatogenesis
0.32GO:0005977glycogen metabolic process
0.32GO:0016310phosphorylation
0.72GO:0004930G-protein coupled receptor activity
0.33GO:0005516calmodulin binding
0.32GO:0016301kinase activity
0.49GO:0005829cytosol
0.43GO:0005886plasma membrane
0.39GO:0045177apical part of cell
0.37GO:0070062extracellular exosome
0.36GO:0009986cell surface
0.30GO:0016021integral component of membrane
sp|Q8IZQ1|WDFY3_HUMAN
WD repeat and FYVE domain-containing protein 3
Search
WDFY3
0.92WD repeat and FYVE domain-containing protein 3
0.62GO:0035973aggrephagy
0.36GO:0007275multicellular organism development
0.59GO:0003831beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
0.58GO:00055451-phosphatidylinositol binding
0.53GO:0046872metal ion binding
0.34GO:0005515protein binding
0.61GO:0034274Atg12-Atg5-Atg16 complex
0.59GO:0097635extrinsic component of autophagosome membrane
0.58GO:0016605PML body
0.58GO:0016234inclusion body
0.53GO:0005635nuclear envelope
0.52GO:0005730nucleolus
0.50GO:0005829cytosol
0.43GO:0005886plasma membrane
0.38GO:0043204perikaryon
0.37GO:0030424axon
0.59EC:2.4.1.38 GO:0003831
sp|Q8IZQ5|SELH_HUMAN
Selenoprotein H
Search
SELENOH
0.97LOW QUALITY PROTEIN: selenoprotein H
0.63GO:0031016pancreas development
0.63GO:0001889liver development
0.62GO:0048565digestive tract development
0.53GO:0045454cell redox homeostasis
0.54GO:0003723RNA binding
0.30GO:0005623cell
sp|Q8IZQ8|MYCD_HUMAN
Myocardin
Search
MYOCD
0.77Phosphatase and actin regulator
0.84GO:2000727positive regulation of cardiac muscle cell differentiation
0.62GO:0051145smooth muscle cell differentiation
0.61GO:1900222negative regulation of amyloid-beta clearance
0.61GO:0003257positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.60GO:0051152positive regulation of smooth muscle cell differentiation
0.59GO:2001015negative regulation of skeletal muscle cell differentiation
0.59GO:2000587negative regulation of platelet-derived growth factor receptor-beta signaling pathway
0.59GO:0001560regulation of cell growth by extracellular stimulus
0.58GO:0045987positive regulation of smooth muscle contraction
0.58GO:1900239regulation of phenotypic switching
0.76GO:0003713transcription coactivator activity
0.56GO:0070412R-SMAD binding
0.56GO:0001046core promoter sequence-specific DNA binding
0.56GO:0035035histone acetyltransferase binding
0.55GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55GO:0001076transcription factor activity, RNA polymerase II transcription factor binding
0.54GO:0042826histone deacetylase binding
0.52GO:0000987proximal promoter sequence-specific DNA binding
0.51GO:0008134transcription factor binding
0.42GO:0045296cadherin binding
0.59GO:0005634nucleus
0.49GO:0000785chromatin
0.47GO:0070013intracellular organelle lumen
0.35GO:0005667transcription factor complex
sp|Q8IZR5|CKLF4_HUMAN
CKLF-like MARVEL transmembrane domain-containing protein 4
Search
CMTM4
0.97CKLF like MARVEL transmembrane domain containing 4
0.38GO:0010469regulation of receptor activity
0.38GO:0006935chemotaxis
0.33GO:0043312neutrophil degranulation
0.39GO:0005125cytokine activity
0.38GO:0005615extracellular space
0.34GO:1903561extracellular vesicle
0.34GO:0035579specific granule membrane
0.34GO:0035577azurophil granule membrane
0.32GO:0005886plasma membrane
0.30GO:0031224intrinsic component of membrane
sp|Q8IZS5|OFCC1_HUMAN
Orofacial cleft 1 candidate gene 1 protein
Search
OFCC1
0.97Orofacial cleft 1 candidate gene 1 protein homolog
0.46GO:0005515protein binding
0.43GO:0048471perinuclear region of cytoplasm
0.41GO:0015630microtubule cytoskeleton
0.40GO:0005783endoplasmic reticulum
0.40GO:0005829cytosol
0.30GO:0044425membrane part
sp|Q8IZS6|TC1D3_HUMAN
Tctex1 domain-containing protein 3
Search
TCTE3
0.97T-complex-associated-testis-expressed 3
0.62GO:0007018microtubule-based movement
0.56GO:0003774motor activity
0.44GO:0005515protein binding
0.41GO:0046872metal ion binding
0.71GO:0030286dynein complex
0.69GO:0036126sperm flagellum
0.62GO:0019898extrinsic component of membrane
0.59GO:0071564npBAF complex
0.57GO:0005874microtubule
0.42GO:0005737cytoplasm
sp|Q8IZS7|CLCL1_HUMAN
C-type lectin-like domain family 1
Search
sp|Q8IZS8|CA2D3_HUMAN
Voltage-dependent calcium channel subunit alpha-2/delta-3
Search
CACNA2D3
0.93Voltage-dependent calcium channel subunit alpha-2/delta-3
0.51GO:0034765regulation of ion transmembrane transport
0.51GO:0070588calcium ion transmembrane transport
0.45GO:0061337cardiac conduction
0.39GO:0065009regulation of molecular function
0.52GO:0005262calcium channel activity
0.50GO:0022832voltage-gated channel activity
0.49GO:0022839ion gated channel activity
0.49GO:0008381mechanosensitive ion channel activity
0.45GO:0005246calcium channel regulator activity
0.41GO:0046872metal ion binding
0.43GO:0005891voltage-gated calcium channel complex
sp|Q8IZT6|ASPM_HUMAN
Abnormal spindle-like microcephaly-associated protein
Search
ASPM
0.68Abnormal spindle microtubule assembly
0.80GO:0007051spindle organization
0.62GO:0045769negative regulation of asymmetric cell division
0.60GO:0051661maintenance of centrosome location
0.60GO:0021873forebrain neuroblast division
0.59GO:0002052positive regulation of neuroblast proliferation
0.58GO:0097150neuronal stem cell population maintenance
0.57GO:0021987cerebral cortex development
0.57GO:0051653spindle localization
0.57GO:0008584male gonad development
0.57GO:0090263positive regulation of canonical Wnt signaling pathway
0.58GO:0005516calmodulin binding
0.37GO:0019901protein kinase binding
0.60GO:0036449microtubule minus-end
0.58GO:0097431mitotic spindle pole
0.58GO:0072687meiotic spindle
0.56GO:0030496midbody
0.48GO:0005634nucleus
0.41GO:0005737cytoplasm
0.38GO:0016324apical plasma membrane
0.37GO:0005813centrosome
0.30GO:0016021integral component of membrane
sp|Q8IZT8|HS3S5_HUMAN
Heparan sulfate glucosamine 3-O-sulfotransferase 5
Search
HS3ST5
0.57Sulfotransferase
0.60GO:0015015heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.58GO:0046596regulation of viral entry into host cell
0.57GO:0050819negative regulation of coagulation
0.56GO:0006477protein sulfation
0.39GO:0070925organelle assembly
0.39GO:0044782cilium organization
0.39GO:0120031plasma membrane bounded cell projection assembly
0.38GO:0055013cardiac muscle cell development
0.38GO:0060047heart contraction
0.37GO:0031032actomyosin structure organization
0.77GO:0008146sulfotransferase activity
0.30GO:0016020membrane
0.77EC:2.8.2 GO:0008146
sp|Q8IZT9|FAM9C_HUMAN
Protein FAM9C
Search
sp|Q8IZU0|FAM9B_HUMAN
Protein FAM9B
Search
sp|Q8IZU1|FAM9A_HUMAN
Protein FAM9A
Search
0.57GO:0006383transcription by RNA polymerase III
0.45GO:0048666neuron development
0.42GO:0120036plasma membrane bounded cell projection organization
0.41GO:0046530photoreceptor cell differentiation
0.40GO:0007601visual perception
0.39GO:0051290protein heterotetramerization
0.39GO:0050962detection of light stimulus involved in sensory perception
0.39GO:0045494photoreceptor cell maintenance
0.39GO:0007018microtubule-based movement
0.38GO:0051480regulation of cytosolic calcium ion concentration
0.52GO:0003899DNA-directed 5'-3' RNA polymerase activity
0.43GO:0008270zinc ion binding
0.40GO:0005223intracellular cGMP activated cation channel activity
0.40GO:0005222intracellular cAMP activated cation channel activity
0.39GO:0016787hydrolase activity
0.39GO:0030553cGMP binding
0.38GO:0016301kinase activity
0.38GO:0008092cytoskeletal protein binding
0.38GO:0140096catalytic activity, acting on a protein
0.38GO:0005198structural molecule activity
0.49GO:0000790nuclear chromatin
0.44GO:0005883neurofilament
0.43GO:0005666DNA-directed RNA polymerase III complex
0.41GO:0001750photoreceptor outer segment
0.40GO:0017071intracellular cyclic nucleotide activated cation channel complex
0.39GO:0043195terminal bouton
0.37GO:0032391photoreceptor connecting cilium
0.37GO:0036126sperm flagellum
0.37GO:0036064ciliary basal body
0.36GO:0009507chloroplast
0.52EC:2.7.7.6 GO:0003899
sp|Q8IZU2|WDR17_HUMAN
WD repeat-containing protein 17
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WDR17
0.97WD repeat-containing protein 17
0.30GO:0003824catalytic activity
0.46GO:0005737cytoplasm
sp|Q8IZU3|SYCP3_HUMAN
Synaptonemal complex protein 3
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SYCP3
0.97Synaptonemal complex protein 3
0.85GO:0035093spermatogenesis, exchange of chromosomal proteins
0.60GO:0051321meiotic cell cycle
0.46GO:0051301cell division
0.45GO:0000280nuclear division
0.44GO:0070193synaptonemal complex organization
0.43GO:1990830cellular response to leukemia inhibitory factor
0.43GO:0000731DNA synthesis involved in DNA repair
0.43GO:0022402cell cycle process
0.43GO:0035825homologous recombination
0.42GO:0007292female gamete generation
0.41GO:0003677DNA binding
0.41GO:0046982protein heterodimerization activity
0.85GO:0000795synaptonemal complex
0.51GO:0000775chromosome, centromeric region
0.44GO:0001673male germ cell nucleus
0.37GO:0005654nucleoplasm
0.30GO:0016020membrane
sp|Q8IZU8|DSEL_HUMAN
Dermatan-sulfate epimerase-like protein
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DSEL
0.97Dermatan sulfate epimerase-2
0.49GO:0030205dermatan sulfate metabolic process
0.47GO:0030204chondroitin sulfate metabolic process
0.38GO:0050651dermatan sulfate proteoglycan biosynthetic process
0.35GO:0006024glycosaminoglycan biosynthetic process
0.35GO:0072330monocarboxylic acid biosynthetic process
0.35GO:0044272sulfur compound biosynthetic process
0.71GO:0008146sulfotransferase activity
0.50GO:0047757chondroitin-glucuronate 5-epimerase activity
0.35GO:0005794Golgi apparatus
0.34GO:0098588bounding membrane of organelle
0.34GO:0031984organelle subcompartment
0.33GO:0005783endoplasmic reticulum
0.33GO:0005654nucleoplasm
0.33GO:0005829cytosol
0.30GO:0016021integral component of membrane
0.71EC:2.8.2 GO:0008146
sp|Q8IZU9|KIRR3_HUMAN
Kin of IRRE-like protein 3
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KIRREL3
0.95Membrane protein KIRRE
0.70GO:0021740principal sensory nucleus of trigeminal nerve development
0.68GO:0002121inter-male aggressive behavior
0.68GO:0072102glomerulus morphogenesis
0.65GO:0021766hippocampus development
0.64GO:0007416synapse assembly
0.64GO:0001764neuron migration
0.61GO:0030097hemopoiesis
0.60GO:0048812neuron projection morphogenesis
0.60GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
0.66GO:0043198dendritic shaft
0.61GO:0030424axon
0.53GO:0005576extracellular region
0.46GO:0005886plasma membrane
0.30GO:0016021integral component of membrane