Queries 12001 to 13000

GO:0008168

sp|Q7Z4H3|HDDC2_HUMAN
HD domain-containing protein 2
Search

HDDC2

0.94	HD domain-containing protein 2

0.36	GO:0005515	protein binding
0.36	GO:0016787	hydrolase activity

0.59	GO:0005739	mitochondrion
0.43	GO:0070062	extracellular exosome

0.36

GO:0016787

sp|Q7Z4H4|ADM2_HUMAN
ADM2
Search

ADM2

0.97	Adrenomedullin 2

0.75	GO:0010469	regulation of receptor activity
0.57	GO:0045766	positive regulation of angiogenesis
0.56	GO:0001525	angiogenesis
0.51	GO:0010628	positive regulation of gene expression
0.47	GO:0006468	protein phosphorylation
0.45	GO:0045776	negative regulation of blood pressure
0.44	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.44	GO:0007631	feeding behavior
0.44	GO:0007586	digestion
0.37	GO:0019310	inositol catabolic process

0.79	GO:0005179	hormone activity
0.53	GO:0032403	protein complex binding
0.37	GO:0050113	inositol oxygenase activity
0.34	GO:0005506	iron ion binding

0.66	GO:0005576	extracellular region
0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.37	EC:1.13.99.1	GO:0050113
0.37	KEGG:R01184	GO:0050113

sp|Q7Z4H7|HAUS6_HUMAN
HAUS augmin-like complex subunit 6
Search

HAUS6

0.96	HAUS augmin like complex subunit 6

0.82	GO:0051225	spindle assembly
0.67	GO:0007098	centrosome cycle
0.41	GO:0097711	ciliary basal body-plasma membrane docking
0.40	GO:0000086	G2/M transition of mitotic cell cycle
0.39	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.36	GO:0051301	cell division

0.36

GO:0005515

protein binding

0.84	GO:0070652	HAUS complex
0.66	GO:0016607	nuclear speck
0.64	GO:0005813	centrosome
0.58	GO:0005829	cytosol
0.38	GO:0005819	spindle
0.37	GO:0005874	microtubule

sp|Q7Z4H8|KDEL2_HUMAN
KDEL motif-containing protein 2
Search

KDELC2

0.97	KDEL motif-containing protein 2

0.64	GO:0006664	glycolipid metabolic process
0.40	GO:0006886	intracellular protein transport
0.34	GO:0055114	oxidation-reduction process

0.67	GO:0046527	glucosyltransferase activity
0.42	GO:0017137	Rab GTPase binding
0.34	GO:0016491	oxidoreductase activity

0.80	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.67

GO:0046527

sp|Q7Z4H9|F220A_HUMAN
Protein FAM220A
Search

C7ORF70

0.97	STAT3-interacting protein as a repressor

sp|Q7Z4I7|LIMS2_HUMAN
LIM and senescent cell antigen-like-containing domain protein 2
Search

LIMS2

0.78	LIM and senescent cell antigen-like-containing domain protein 2

0.62	GO:0045216	cell-cell junction organization
0.55	GO:2000346	negative regulation of hepatocyte proliferation
0.53	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.52	GO:2000178	negative regulation of neural precursor cell proliferation
0.48	GO:0043066	negative regulation of apoptotic process
0.48	GO:0098609	cell-cell adhesion
0.41	GO:0051894	positive regulation of focal adhesion assembly
0.41	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.41	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.41	GO:0033209	tumor necrosis factor-mediated signaling pathway

0.53	GO:0046872	metal ion binding
0.39	GO:0019901	protein kinase binding
0.34	GO:0019904	protein domain specific binding

0.62	GO:0005925	focal adhesion
0.45	GO:0005886	plasma membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005911	cell-cell junction
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.32	GO:0043234	protein complex

sp|Q7Z4J2|GL6D1_HUMAN
Glycosyltransferase 6 domain-containing protein 1
Search

GLT6D1

0.97	Glycosyltransferase 6 domain-containing protein 1

0.60	GO:0005975	carbohydrate metabolic process
0.52	GO:0030259	lipid glycosylation
0.50	GO:0009247	glycolipid biosynthetic process
0.47	GO:0033580	protein galactosylation at cell surface
0.37	GO:0006687	glycosphingolipid metabolic process
0.37	GO:0030148	sphingolipid biosynthetic process

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.44	GO:0008194	UDP-glycosyltransferase activity
0.36	GO:0046872	metal ion binding

0.50	GO:0005794	Golgi apparatus
0.49	GO:0031982	vesicle
0.41	GO:0098588	bounding membrane of organelle
0.41	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016758

sp|Q7Z4K8|TRI46_HUMAN
Tripartite motif-containing protein 46
Search

TRIM46

0.97	Tripartite motif-containing protein 46

0.58	GO:0048490	anterograde synaptic vesicle transport
0.58	GO:0099612	protein localization to axon
0.56	GO:0001764	neuron migration
0.55	GO:0001578	microtubule bundle formation
0.54	GO:0007409	axonogenesis

0.62	GO:0008270	zinc ion binding
0.35	GO:0008017	microtubule binding

0.60	GO:1990769	proximal neuron projection
0.59	GO:0043194	axon initial segment
0.57	GO:1904115	axon cytoplasm
0.37	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z4L0|COX8C_HUMAN
Cytochrome c oxidase subunit 8C, mitochondrial
Search

COX8C

0.97	Cytochrome c oxidase subunit 8C, mitochondrial

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.44	GO:0006119	oxidative phosphorylation
0.44	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.58	GO:0005739	mitochondrion
0.48	GO:0045277	respiratory chain complex IV
0.43	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:1.9.3

GO:0016676

sp|Q7Z4L5|TT21B_HUMAN
Tetratricopeptide repeat protein 21B
Search

TTC21B

0.95	Tetratricopeptide repeat protein 21B

0.76	GO:0035721	intraciliary retrograde transport
0.76	GO:0061512	protein localization to cilium
0.72	GO:0021798	forebrain dorsal/ventral pattern formation
0.69	GO:0021591	ventricular system development
0.68	GO:0008589	regulation of smoothened signaling pathway
0.66	GO:0007224	smoothened signaling pathway
0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.51	GO:0007369	gastrulation
0.38	GO:0035735	intraciliary transport involved in cilium assembly
0.36	GO:0006486	protein glycosylation

0.54	GO:0042802	identical protein binding
0.35	GO:0030246	carbohydrate binding
0.35	GO:0016757	transferase activity, transferring glycosyl groups

0.76	GO:0030991	intraciliary transport particle A
0.66	GO:0005929	cilium
0.61	GO:0000790	nuclear chromatin
0.38	GO:0005856	cytoskeleton
0.37	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016757

sp|Q7Z4L9|PPR42_HUMAN
Protein phosphatase 1 regulatory subunit 42
Search

PPP1R42

0.97	LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 42

0.77	GO:0010921	regulation of phosphatase activity
0.33	GO:0006508	proteolysis
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.82	GO:0070840	dynein complex binding
0.72	GO:0015631	tubulin binding
0.72	GO:0003779	actin binding
0.34	GO:0004222	metalloendopeptidase activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0004930	G-protein coupled receptor activity

0.86	GO:0002177	manchette
0.76	GO:0005813	centrosome
0.37	GO:0005737	cytoplasm
0.35	GO:0008180	COP9 signalosome
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004222

sp|Q7Z4M0|RE114_HUMAN
Meiotic recombination protein REC114
Search

REC114

0.97	Meiotic recombination protein REC114

0.78	GO:0051321	meiotic cell cycle
0.65	GO:0006310	DNA recombination

0.51

GO:0005515

protein binding

sp|Q7Z4N2|TRPM1_HUMAN
Transient receptor potential cation channel subfamily M member 1
Search

TRPM1

0.96	Long transient receptor potential channel 1

0.83	GO:0007216	G-protein coupled glutamate receptor signaling pathway
0.79	GO:0051262	protein tetramerization
0.76	GO:0071482	cellular response to light stimulus
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0006812	cation transport
0.48	GO:0007600	sensory perception
0.48	GO:0016048	detection of temperature stimulus
0.47	GO:0046548	retinal rod cell development
0.44	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0051649	establishment of localization in cell

0.72	GO:0005261	cation channel activity
0.43	GO:0015085	calcium ion transmembrane transporter activity
0.43	GO:0022839	ion gated channel activity
0.43	GO:0008381	mechanosensitive ion channel activity

0.47	GO:0035841	new growing cell tip
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q7Z4N8|P4HA3_HUMAN
Prolyl 4-hydroxylase subunit alpha-3
Search

P4HA3

0.79	Prolyl 4-hydroxylase, alpha polypeptide III

0.81	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0005975	carbohydrate metabolic process

0.82	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.72	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.34	GO:0005515	protein binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016868	intramolecular transferase activity, phosphotransferases

0.68	GO:0005783	endoplasmic reticulum
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.34	GO:1990204	oxidoreductase complex
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.14.11.2	GO:0004656
0.82	KEGG:R03219	GO:0004656

sp|Q7Z4P5|GDF7_HUMAN
Growth/differentiation factor 7
Search

0.90	Growth differentiation factor 7

0.76	GO:0010469	regulation of receptor activity
0.64	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.63	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.63	GO:0032924	activin receptor signaling pathway
0.61	GO:0030509	BMP signaling pathway
0.60	GO:2001051	positive regulation of tendon cell differentiation
0.60	GO:0021509	roof plate formation
0.58	GO:0060395	SMAD protein signal transduction
0.57	GO:0045666	positive regulation of neuron differentiation
0.57	GO:0021527	spinal cord association neuron differentiation

0.78	GO:0008083	growth factor activity
0.54	GO:0042803	protein homodimerization activity
0.53	GO:0005160	transforming growth factor beta receptor binding
0.51	GO:0005125	cytokine activity
0.36	GO:0036122	BMP binding
0.32	GO:0003677	DNA binding

0.66	GO:0005576	extracellular region
0.34	GO:0005720	nuclear heterochromatin
0.33	GO:0005750	mitochondrial respiratory chain complex III

sp|Q7Z4Q2|HEAT3_HUMAN
HEAT repeat-containing protein 3
Search

HEATR3

0.97	HEAT repeat-containing protein 3

0.78	GO:0006606	protein import into nucleus
0.74	GO:0042273	ribosomal large subunit biogenesis

0.69	GO:0051082	unfolded protein binding
0.40	GO:0016779	nucleotidyltransferase activity

0.40

GO:0016779

sp|Q7Z4R8|CF120_HUMAN
UPF0669 protein C6orf120
Search

0.62	GO:0006915	apoptotic process
0.50	GO:0043312	neutrophil degranulation
0.48	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:0006281	DNA repair

0.48	GO:0004518	nuclease activity
0.42	GO:0003677	DNA binding
0.36	GO:0140097	catalytic activity, acting on DNA

0.60	GO:0005576	extracellular region
0.51	GO:0035578	azurophil granule lumen
0.30	GO:0016020	membrane

0.48

EC:3.1

GO:0004518

sp|Q7Z4S6|KI21A_HUMAN
Kinesin-like protein KIF21A
Search

KIF21A

0.94	Kinesin family member 21A

0.74

GO:0007018

microtubule-based movement

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0016887	ATPase activity

0.55	GO:0005829	cytosol
0.54	GO:0005871	kinesin complex
0.47	GO:0005886	plasma membrane

0.45

GO:0016887

sp|Q7Z4S9|SH2D6_HUMAN
SH2 domain-containing protein 6
Search

SH2D6

0.96	SH2 domain-containing protein 6

0.75	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.73	GO:0009967	positive regulation of signal transduction
0.71	GO:0006955	immune response
0.60	GO:0035556	intracellular signal transduction

0.85	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity
0.82	GO:0005070	SH3/SH2 adaptor activity
0.41	GO:0003723	RNA binding

0.47

GO:0005737

cytoplasm

sp|Q7Z4T8|GLTL5_HUMAN
Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5
Search

GALNT11

0.57	Polypeptide N-acetylgalactosaminyltransferase

0.68	GO:0006486	protein glycosylation
0.53	GO:0018210	peptidyl-threonine modification
0.51	GO:0007286	spermatid development
0.38	GO:0061314	Notch signaling involved in heart development
0.38	GO:0007220	Notch receptor processing
0.37	GO:0008593	regulation of Notch signaling pathway
0.37	GO:0007368	determination of left/right symmetry
0.37	GO:0060271	cilium assembly

0.63	GO:0030246	carbohydrate binding
0.60	GO:0016757	transferase activity, transferring glycosyl groups
0.54	GO:0005112	Notch binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0046872	metal ion binding

0.66	GO:0000139	Golgi membrane
0.39	GO:0031902	late endosome membrane
0.30	GO:0016021	integral component of membrane

0.60

GO:0016757

sp|Q7Z4T9|CFA91_HUMAN
Cilia- and flagella-associated protein 91
Search

MAATS1

0.84	MYCBP associated and testis expressed 1

0.65	GO:0003341	cilium movement
0.53	GO:0006426	glycyl-tRNA aminoacylation
0.45	GO:0043401	steroid hormone mediated signaling pathway
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:0010468	regulation of gene expression

0.53	GO:0004820	glycine-tRNA ligase activity
0.45	GO:0003707	steroid hormone receptor activity
0.45	GO:0005515	protein binding
0.44	GO:0043565	sequence-specific DNA binding
0.43	GO:0008270	zinc ion binding
0.43	GO:0003700	DNA binding transcription factor activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0001536	radial spoke stalk
0.62	GO:0031514	motile cilium
0.50	GO:0005739	mitochondrion
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.53

EC:6.1.1.14

GO:0004820

sp|Q7Z4U5|CF201_HUMAN
Uncharacterized protein C6orf201
Search

sp|Q7Z4V0|ZN438_HUMAN
Zinc finger protein 438
Search

ZNF438

0.97	Zinc finger protein 438

0.44	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process

0.51	GO:0003676	nucleic acid binding
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0046872	metal ion binding
0.34	GO:0003735	structural constituent of ribosome

0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.33	GO:0005840	ribosome

sp|Q7Z4V5|HDGR2_HUMAN
Hepatoma-derived growth factor-related protein 2
Search

HDGFL2

0.95	Hepatoma-derived growth factor-related protein 2

0.79

GO:0030307

positive regulation of cell growth

0.59	GO:0003682	chromatin binding
0.52	GO:0005515	protein binding
0.38	GO:0003677	DNA binding

0.56

GO:0005634

nucleus

sp|Q7Z4W1|DCXR_HUMAN
L-xylulose reductase
Search

DCXR

0.70	Dicarbonyl and L-xylulose reductase

0.54	GO:0051262	protein tetramerization
0.53	GO:0005997	xylulose metabolic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0051260	protein homooligomerization
0.48	GO:0006006	glucose metabolic process
0.44	GO:0006739	NADP metabolic process
0.41	GO:0042732	D-xylose metabolic process
0.37	GO:0019640	glucuronate catabolic process to xylulose 5-phosphate
0.35	GO:0006734	NADH metabolic process
0.33	GO:0007389	pattern specification process

0.59	GO:0050038	L-xylulose reductase (NADP+) activity
0.49	GO:0042802	identical protein binding
0.47	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.43	GO:0004090	carbonyl reductase (NADPH) activity
0.41	GO:0043621	protein self-association
0.37	GO:0047880	erythrulose reductase activity
0.36	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.32	GO:0046872	metal ion binding

0.54	GO:0005881	cytoplasmic microtubule
0.49	GO:0005902	microvillus
0.49	GO:0005903	brush border
0.37	GO:0043227	membrane-bounded organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.35	GO:0097223	sperm part
0.35	GO:0016324	apical plasma membrane
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0012505	endomembrane system

0.59	EC:1.1.1.10	GO:0050038
0.59	KEGG:R01904	GO:0050038

sp|Q7Z4W2|LYZL2_HUMAN
Lysozyme-like protein 2
Search

0.49	Lysozyme C, non-stomach isozyme

0.59	GO:0042742	defense response to bacterium
0.54	GO:0019835	cytolysis
0.47	GO:0016998	cell wall macromolecule catabolic process
0.40	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.38	GO:0031640	killing of cells of other organism
0.36	GO:0007586	digestion
0.33	GO:0002159	desmosome assembly
0.33	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.32	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0045824	negative regulation of innate immune response

0.77	GO:0003796	lysozyme activity
0.37	GO:0042802	identical protein binding
0.33	GO:0045294	alpha-catenin binding
0.33	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0045296	cadherin binding
0.32	GO:0003723	RNA binding
0.32	GO:0005198	structural molecule activity

0.47	GO:0005615	extracellular space
0.40	GO:0097223	sperm part
0.39	GO:0097729	9+2 motile cilium
0.38	GO:0044441	ciliary part
0.35	GO:0005886	plasma membrane
0.34	GO:0030667	secretory granule membrane
0.33	GO:0044437	vacuolar part
0.33	GO:0009986	cell surface
0.32	GO:0005913	cell-cell adherens junction
0.32	GO:0019898	extrinsic component of membrane

0.77

EC:3.2.1.17

GO:0003796

sp|Q7Z4W3|KR193_HUMAN
Keratin-associated protein 19-3
Search

0.97	High tyrosine-glycine keratin-associated protein 19.1

0.58	GO:0031424	keratinization
0.42	GO:0016560	protein import into peroxisome matrix, docking
0.37	GO:0070830	bicellular tight junction assembly
0.36	GO:0007010	cytoskeleton organization
0.35	GO:0071709	membrane assembly
0.35	GO:0006413	translational initiation

0.39	GO:0005515	protein binding
0.38	GO:0005198	structural molecule activity
0.37	GO:0030246	carbohydrate binding
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0004386	helicase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005882	intermediate filament
0.49	GO:0005829	cytosol
0.40	GO:0042579	microbody
0.37	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0016327	apicolateral plasma membrane
0.36	GO:0016324	apical plasma membrane
0.36	GO:0030139	endocytic vesicle
0.36	GO:0005923	bicellular tight junction
0.34	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

sp|Q7Z4Y8|AT5L2_HUMAN
ATP synthase subunit g 2, mitochondrial
Search

ATP5L

0.87	ATP synthase subunit gserine-threonine

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.46	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.36	GO:0051568	histone H3-K4 methylation
0.35	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0016567	protein ubiquitination
0.33	GO:0006355	regulation of transcription, DNA-templated

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.47	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.46	GO:0019829	cation-transporting ATPase activity
0.36	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.36	GO:0047624	adenosine-tetraphosphatase activity
0.36	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.35	GO:0034450	ubiquitin-ubiquitin ligase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0003677	DNA binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.37	GO:0070062	extracellular exosome
0.36	GO:0071339	MLL1 complex
0.34	GO:0000151	ubiquitin ligase complex
0.30	GO:0016021	integral component of membrane

0.36

EC:3.6.1.14

GO:0047624

sp|Q7Z553|MDGA2_HUMAN
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
Search

MDGA2

0.97	MAM domain-containing glycosylphosphatidylinositol anchor protein 2

0.42	GO:0021611	facial nerve formation
0.41	GO:0021731	trigeminal motor nucleus development
0.41	GO:1905483	regulation of motor neuron migration
0.38	GO:0021522	spinal cord motor neuron differentiation
0.37	GO:0007389	pattern specification process
0.36	GO:0006501	C-terminal protein lipidation

0.39	GO:0031225	anchored component of membrane
0.35	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q7Z569|BRAP_HUMAN
BRCA1-associated protein
Search

BRAP

0.79	BRCA1 associated protein variant (Fragment)

0.54	GO:0007265	Ras protein signal transduction
0.53	GO:0000165	MAPK cascade
0.50	GO:0009968	negative regulation of signal transduction
0.50	GO:0016567	protein ubiquitination
0.35	GO:0002091	negative regulation of receptor internalization
0.35	GO:0033962	cytoplasmic mRNA processing body assembly
0.35	GO:0034063	stress granule assembly

0.63	GO:0008270	zinc ion binding
0.56	GO:0008139	nuclear localization sequence binding
0.52	GO:0061630	ubiquitin protein ligase activity
0.50	GO:0042802	identical protein binding
0.49	GO:0003676	nucleic acid binding
0.35	GO:0005154	epidermal growth factor receptor binding
0.34	GO:0008022	protein C-terminus binding

0.53	GO:0031965	nuclear membrane
0.51	GO:0000151	ubiquitin ligase complex
0.48	GO:0005829	cytosol
0.34	GO:0005844	polysome
0.34	GO:0010494	cytoplasmic stress granule
0.34	GO:0005802	trans-Golgi network
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q7Z570|Z804A_HUMAN
Zinc finger protein 804A
Search

ZNF804A

0.50	Zinc finger protein (Fragment)

0.66	GO:0010976	positive regulation of neuron projection development
0.59	GO:0010628	positive regulation of gene expression
0.45	GO:1902952	positive regulation of dendritic spine maintenance

0.52	GO:0046872	metal ion binding
0.49	GO:0003676	nucleic acid binding

0.75	GO:1901588	dendritic microtubule
0.69	GO:0043198	dendritic shaft
0.68	GO:0043197	dendritic spine
0.67	GO:0030426	growth cone
0.65	GO:0043025	neuronal cell body
0.51	GO:0005634	nucleus
0.47	GO:0005886	plasma membrane
0.43	GO:0005737	cytoplasm
0.42	GO:0030424	axon
0.42	GO:0098793	presynapse

sp|Q7Z572|SPT21_HUMAN
Spermatogenesis-associated protein 21
Search

SPATA21

0.97	Spermatogenesis-associated protein 21

0.70

GO:0005509

calcium ion binding

sp|Q7Z589|EMSY_HUMAN
BRCA2-interacting transcriptional repressor EMSY
Search

EMSY

0.97	EMSY, BRCA2 interacting transcriptional repressor

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.61

GO:0042803

protein homodimerization activity

0.56

GO:0005654

nucleoplasm

sp|Q7Z591|AKNA_HUMAN
AT-hook-containing transcription factor
Search

AKNA

0.97	AT-hook-containing transcription factor

0.76	GO:0006366	transcription by RNA polymerase II
0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.32	GO:0006508	proteolysis

0.82	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.80	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.32	GO:0008234	cysteine-type peptidase activity

0.83	GO:0001650	fibrillar center
0.78	GO:0005813	centrosome
0.70	GO:0005654	nucleoplasm
0.69	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.32

GO:0008234

sp|Q7Z5A4|PRS42_HUMAN
Serine protease 42
Search

PRSS42

0.59	Testis serine protease 2

0.61	GO:0006508	proteolysis
0.44	GO:0007283	spermatogenesis
0.44	GO:0007281	germ cell development
0.40	GO:0035220	wing disc development
0.40	GO:0051017	actin filament bundle assembly
0.37	GO:0050878	regulation of body fluid levels
0.36	GO:0006959	humoral immune response
0.36	GO:0050817	coagulation
0.36	GO:0072376	protein activation cascade
0.36	GO:0042060	wound healing

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005509	calcium ion binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.32	GO:0005515	protein binding

0.45	GO:0046658	anchored component of plasma membrane
0.40	GO:0005576	extracellular region
0.37	GO:0005737	cytoplasm
0.34	GO:0031983	vesicle lumen
0.33	GO:0097708	intracellular vesicle
0.32	GO:0012505	endomembrane system
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|Q7Z5A7|F19A5_HUMAN
Protein FAM19A5
Search

0.38	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q7Z5A8|F19A3_HUMAN
Protein FAM19A3
Search

0.70	GO:1903979	negative regulation of microglial cell activation
0.69	GO:1903980	positive regulation of microglial cell activation

0.36	GO:0004386	helicase activity
0.35	GO:0005515	protein binding

0.59	GO:0005615	extracellular space
0.55	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|Q7Z5A9|F19A1_HUMAN
Protein FAM19A1
Search

0.58	GO:1903979	negative regulation of microglial cell activation
0.57	GO:1903980	positive regulation of microglial cell activation
0.42	GO:0051930	regulation of sensory perception of pain
0.39	GO:0042391	regulation of membrane potential

0.36

GO:0005515

protein binding

0.62	GO:0005783	endoplasmic reticulum
0.50	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|Q7Z5B4|RIC3_HUMAN
Protein RIC-3
Search

RIC3

0.97	Chaperone protein RIC-3

0.52	GO:0043623	cellular protein complex assembly
0.52	GO:0034394	protein localization to cell surface
0.52	GO:0007271	synaptic transmission, cholinergic
0.51	GO:0006457	protein folding
0.40	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.61	GO:0044183	protein binding involved in protein folding
0.52	GO:0033130	acetylcholine receptor binding
0.32	GO:0046872	metal ion binding

0.52	GO:0005783	endoplasmic reticulum
0.49	GO:0043025	neuronal cell body
0.48	GO:0043005	neuron projection
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.35	GO:0044431	Golgi apparatus part
0.35	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z5D8|NANGN_HUMAN
NANOG neighbor homeobox
Search

NANOGNB

0.97	NANOG neighbor homeobox

0.39	GO:0050794	regulation of cellular process
0.39	GO:0023051	regulation of signaling
0.39	GO:0016477	cell migration
0.38	GO:0048583	regulation of response to stimulus
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0032879	regulation of localization
0.38	GO:0000398	mRNA splicing, via spliceosome
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0050790	regulation of catalytic activity

0.50	GO:0003677	DNA binding
0.38	GO:0005515	protein binding
0.37	GO:0046872	metal ion binding
0.36	GO:0043168	anion binding
0.36	GO:1901265	nucleoside phosphate binding
0.36	GO:0000989	transcription factor activity, transcription factor binding
0.36	GO:0015081	sodium ion transmembrane transporter activity
0.36	GO:0016746	transferase activity, transferring acyl groups
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0036094	small molecule binding

0.56	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.37	GO:0005856	cytoskeleton
0.37	GO:0005829	cytosol
0.36	GO:0048786	presynaptic active zone
0.35	GO:0120114	Sm-like protein family complex
0.35	GO:0005773	vacuole
0.35	GO:0012505	endomembrane system
0.35	GO:0005925	focal adhesion

0.36	EC:2.3	GO:0016746
0.36	KEGG:R01881	GO:0004111

sp|Q7Z5G4|GOGA7_HUMAN
Golgin subfamily A member 7
Search

GOLGA7

0.93	Golgi complex-associated protein of 16 kDa

0.86	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.85	GO:0018345	protein palmitoylation
0.84	GO:0043001	Golgi to plasma membrane protein transport
0.75	GO:0050821	protein stabilization
0.61	GO:0006612	protein targeting to membrane
0.40	GO:0043312	neutrophil degranulation
0.36	GO:0006260	DNA replication

0.64	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.36	GO:0005515	protein binding

0.85	GO:0002178	palmitoyltransferase complex
0.78	GO:0005795	Golgi stack
0.77	GO:0031228	intrinsic component of Golgi membrane
0.43	GO:0070062	extracellular exosome
0.41	GO:1904724	tertiary granule lumen
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.64

GO:0019706

sp|Q7Z5H3|RHG22_HUMAN
Rho GTPase-activating protein 22
Search

ARHGAP22

0.91	Rho GTPase-activating protein 22

0.67	GO:0043547	positive regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.37	GO:0001525	angiogenesis
0.36	GO:0030154	cell differentiation
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.67	GO:0005096	GTPase activator activity
0.35	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0005515	protein binding

0.38	GO:0005925	focal adhesion
0.35	GO:0005634	nucleus
0.34	GO:0005829	cytosol

0.35

GO:0016757

sp|Q7Z5H4|VN1R5_HUMAN
Vomeronasal type-1 receptor 5
Search

0.43	Vomeronasal type-1 receptor

0.82	GO:0019236	response to pheromone
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0007606	sensory perception of chemical stimulus

0.83	GO:0016503	pheromone receptor activity
0.38	GO:0005550	pheromone binding

0.56	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q7Z5H5|VN1R4_HUMAN
Vomeronasal type-1 receptor 4
Search

V1R

0.59	Vomeronasal type-1 receptor

0.81	GO:0019236	response to pheromone
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0007606	sensory perception of chemical stimulus

0.83	GO:0016503	pheromone receptor activity
0.36	GO:0005550	pheromone binding

0.55	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q7Z5J1|DHI1L_HUMAN
Hydroxysteroid 11-beta-dehydrogenase 1-like protein
Search

HSD11B1L

0.67	11-beta-hydroxysteroid dehydrogenase long form

0.52	GO:0055114	oxidation-reduction process
0.33	GO:0006412	translation

0.53	GO:0016491	oxidoreductase activity
0.34	GO:0070403	NAD+ binding
0.34	GO:0003735	structural constituent of ribosome
0.32	GO:0016740	transferase activity

0.50	GO:0005654	nucleoplasm
0.40	GO:0005576	extracellular region
0.34	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0016491

sp|Q7Z5J4|RAI1_HUMAN
Retinoic acid-induced protein 1
Search

RAI1

0.96	Retinoic acid-induced protein 1

0.65	GO:0040015	negative regulation of multicellular organism growth
0.65	GO:0032922	circadian regulation of gene expression
0.59	GO:0001501	skeletal system development
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0006366	transcription by RNA polymerase II

0.63	GO:0035326	enhancer binding
0.52	GO:0046872	metal ion binding
0.45	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0003713	transcription coactivator activity
0.32	GO:0003723	RNA binding

0.55	GO:0005654	nucleoplasm
0.49	GO:0005739	mitochondrion

sp|Q7Z5J8|ANKAR_HUMAN
Ankyrin and armadillo repeat-containing protein
Search

ANKAR

0.97	Ankyrin and armadillo repeat containing

0.42	GO:0006298	mismatch repair
0.39	GO:0034333	adherens junction assembly
0.35	GO:0007165	signal transduction

0.42	GO:0030983	mismatched DNA binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004871	signal transducer activity

0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q7Z5K2|WAPL_HUMAN
Wings apart-like protein homolog
Search

WAPL

0.94	WAPL cohesin release factor a

0.87	GO:0071922	regulation of cohesin loading
0.85	GO:0035562	negative regulation of chromatin binding
0.85	GO:0060623	regulation of chromosome condensation
0.85	GO:0045875	negative regulation of sister chromatid cohesion
0.84	GO:0071168	protein localization to chromatin
0.80	GO:0048146	positive regulation of fibroblast proliferation
0.78	GO:0008156	negative regulation of DNA replication
0.73	GO:0000278	mitotic cell cycle
0.64	GO:0045132	meiotic chromosome segregation
0.63	GO:0009636	response to toxic substance

0.81	GO:0008278	cohesin complex
0.78	GO:0000795	synaptonemal complex
0.69	GO:0000785	chromatin
0.47	GO:0005737	cytoplasm

sp|Q7Z5L0|VMO1_HUMAN
Vitelline membrane outer layer protein 1 homolog
Search

VMO1

0.88	Vitelline membrane outer layer protein 1

0.40

GO:0006629

lipid metabolic process

0.48	GO:0005509	calcium ion binding
0.43	GO:0008081	phosphoric diester hydrolase activity

0.55	GO:0005615	extracellular space
0.45	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005623	cell

0.43

EC:3.1.4

GO:0008081

sp|Q7Z5L2|R3HCL_HUMAN
Coiled-coil domain-containing protein R3HCC1L
Search

R3HCC1L

0.94	Growth inhibition and differentiation-related protein 88

0.47	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding
0.35	GO:0005549	odorant binding

0.63

GO:0035145

exon-exon junction complex

sp|Q7Z5L3|C1QL2_HUMAN
Complement C1q-like protein 2
Search

C1QL2

0.97	Complement component 1, q subcomponent-like 2

0.52	GO:0051259	protein oligomerization
0.50	GO:0050807	regulation of synapse organization

0.57

GO:0042802

identical protein binding

0.70	GO:0005581	collagen trimer
0.63	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z5L4|SPT19_HUMAN
Spermatogenesis-associated protein 19, mitochondrial
Search

SPATA19

0.97	Spermatogenesis-associated protein 19, mitochondrial

0.80	GO:0007283	spermatogenesis
0.72	GO:0030154	cell differentiation
0.70	GO:0007275	multicellular organism development

0.78

GO:0005741

mitochondrial outer membrane

sp|Q7Z5L7|PODN_HUMAN
Podocan
Search

PODN

0.97

Podocan

0.79	GO:0030336	negative regulation of cell migration
0.76	GO:0008285	negative regulation of cell proliferation
0.66	GO:0046426	negative regulation of JAK-STAT cascade
0.62	GO:0006469	negative regulation of protein kinase activity
0.62	GO:0019221	cytokine-mediated signaling pathway
0.32	GO:0006468	protein phosphorylation

0.79	GO:0005518	collagen binding
0.64	GO:0004860	protein kinase inhibitor activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0031012	extracellular matrix
0.70	GO:0005615	extracellular space
0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q7Z5L9|I2BP2_HUMAN
Interferon regulatory factor 2-binding protein 2
Search

IRF2BP2

0.96	Interferon regulatory factor 2-binding protein 2

0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0006351	transcription, DNA-templated
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II

0.44	GO:0046872	metal ion binding
0.44	GO:0003714	transcription corepressor activity

0.66	GO:0005654	nucleoplasm
0.37	GO:0005737	cytoplasm

sp|Q7Z5M5|TMC3_HUMAN
Transmembrane channel-like protein 3
Search

TMC3

0.83	Transmembrane channel-like protein 3

0.35

GO:0006811

ion transport

0.30

GO:0016021

integral component of membrane

sp|Q7Z5M8|AB12B_HUMAN
Protein ABHD12B
Search

ABHD12B

0.86	Abhydrolase domain-containing protein 12

0.54	GO:0052651	monoacylglycerol catabolic process
0.53	GO:0006660	phosphatidylserine catabolic process
0.51	GO:0010996	response to auditory stimulus
0.51	GO:0007628	adult walking behavior
0.50	GO:0002084	protein depalmitoylation
0.40	GO:0048899	anterior lateral line development
0.40	GO:0036269	swimming behavior
0.39	GO:0048919	posterior lateral line neuromast development
0.39	GO:0010842	retina layer formation
0.38	GO:0042552	myelination

0.72	GO:0047372	acylglycerol lipase activity
0.50	GO:0008474	palmitoyl-(protein) hydrolase activity
0.50	GO:0004622	lysophospholipase activity

0.51	GO:0032839	dendrite cytoplasm
0.51	GO:0032281	AMPA glutamate receptor complex
0.32	GO:0005739	mitochondrion

0.72

EC:3.1.1.23

GO:0047372

sp|Q7Z5N4|SDK1_HUMAN
Protein sidekick-1
Search

SDK1

0.97	Sidekick cell adhesion molecule 1

0.58	GO:0048148	behavioral response to cocaine
0.57	GO:0060998	regulation of dendritic spine development
0.42	GO:0010842	retina layer formation
0.41	GO:0007416	synapse assembly
0.40	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.36	GO:0045216	cell-cell junction organization
0.33	GO:0060219	camera-type eye photoreceptor cell differentiation
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.39	GO:0042802	identical protein binding
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.39	GO:0045202	synapse
0.39	GO:0030054	cell junction
0.36	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q7Z5P4|DHB13_HUMAN
17-beta-hydroxysteroid dehydrogenase 13
Search

HSD17B11

0.90	17-beta-hydroxysteroid dehydrogenase 13

0.70	GO:0046889	positive regulation of lipid biosynthetic process
0.66	GO:0006710	androgen catabolic process
0.45	GO:0055114	oxidation-reduction process
0.41	GO:0034389	lipid particle organization

0.59

GO:0016229

steroid dehydrogenase activity

0.78	GO:0005811	lipid droplet
0.41	GO:0005737	cytoplasm
0.41	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.59

EC:1.1.1

GO:0016229

sp|Q7Z5P9|MUC19_HUMAN
Mucin-19
Search

0.65	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.62	GO:0016266	O-glycan processing
0.49	GO:0060689	cell differentiation involved in salivary gland development
0.47	GO:0050728	negative regulation of inflammatory response
0.47	GO:0002244	hematopoietic progenitor cell differentiation
0.40	GO:0043030	regulation of macrophage activation
0.38	GO:0042742	defense response to bacterium
0.34	GO:0007605	sensory perception of sound
0.34	GO:0010466	negative regulation of peptidase activity
0.33	GO:0000128	flocculation

0.35	GO:0005515	protein binding
0.34	GO:0030414	peptidase inhibitor activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.64	GO:0005796	Golgi lumen
0.56	GO:0031982	vesicle
0.44	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q7Z5Q1|CPEB2_HUMAN
Cytoplasmic polyadenylation element-binding protein 2
Search

CPEB2

0.90	Cytoplasmic polyadenylation element binding protein 2 variant B

0.71	GO:0006417	regulation of translation
0.50	GO:0034249	negative regulation of cellular amide metabolic process
0.50	GO:0071456	cellular response to hypoxia
0.49	GO:0032869	cellular response to insulin stimulus
0.48	GO:0032269	negative regulation of cellular protein metabolic process
0.48	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.47	GO:0071243	cellular response to arsenic-containing substance
0.46	GO:0010629	negative regulation of gene expression
0.43	GO:0034599	cellular response to oxidative stress
0.41	GO:0034260	negative regulation of GTPase activity

0.83	GO:0003730	mRNA 3'-UTR binding
0.82	GO:0045182	translation regulator activity
0.47	GO:0043022	ribosome binding
0.47	GO:0017091	AU-rich element binding
0.45	GO:0008187	poly-pyrimidine tract binding
0.43	GO:0008135	translation factor activity, RNA binding
0.42	GO:0005095	GTPase inhibitor activity
0.41	GO:0043024	ribosomal small subunit binding
0.40	GO:0043023	ribosomal large subunit binding
0.35	GO:0005515	protein binding

0.54	GO:1990124	messenger ribonucleoprotein complex
0.46	GO:0043005	neuron projection
0.46	GO:0045202	synapse
0.44	GO:0005844	polysome
0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0036477	somatodendritic compartment
0.36	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0012505	endomembrane system

0.33

GO:0016705

sp|Q7Z5Q5|DPOLN_HUMAN
DNA polymerase nu
Search

POLN

0.97	DNA polymerase nu

0.70	GO:0006261	DNA-dependent DNA replication
0.66	GO:0071897	DNA biosynthetic process
0.62	GO:0006301	postreplication repair
0.60	GO:0036297	interstrand cross-link repair
0.57	GO:0000724	double-strand break repair via homologous recombination
0.42	GO:0022616	DNA strand elongation
0.39	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:0051225	spindle assembly
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.70	GO:0003887	DNA-directed DNA polymerase activity
0.60	GO:0030332	cyclin binding
0.54	GO:0003677	DNA binding
0.47	GO:0004527	exonuclease activity
0.32	GO:0003735	structural constituent of ribosome

0.53	GO:0005654	nucleoplasm
0.39	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.36	GO:0070652	HAUS complex
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.70

EC:2.7.7.7

GO:0003887

sp|Q7Z5R6|AB1IP_HUMAN
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
Search

APBB1IP

0.97	Amyloid beta A4 protein-binding family B member 1-interacting protein isoform A

0.62	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.59	GO:0007165	signal transduction
0.53	GO:0045785	positive regulation of cell adhesion

0.35

GO:0005515

protein binding

0.59	GO:0042101	T cell receptor complex
0.49	GO:0005829	cytosol
0.38	GO:0030027	lamellipodium
0.38	GO:0005856	cytoskeleton
0.38	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z5S9|TM144_HUMAN
Transmembrane protein 144
Search

TMEM144

0.97	Transmembrane protein 144

0.72

GO:0034219

carbohydrate transmembrane transport

0.71

GO:0015144

carbohydrate transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|Q7Z5U6|WDR53_HUMAN
WD repeat-containing protein 53
Search

WDR53

0.97	WD repeat-containing protein 53

0.33	GO:0051301	cell division
0.33	GO:0007049	cell cycle
0.33	GO:0007165	signal transduction

0.48	GO:0005737	cytoplasm
0.34	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z5V6|PPR32_HUMAN
Protein phosphatase 1 regulatory subunit 32
Search

PPP1R32

0.63	Succinate dehydrogenase assembly factor 2, mitochondrial

0.39	GO:0018293	protein-FAD linkage
0.39	GO:0006121	mitochondrial electron transport, succinate to ubiquinone

0.82

GO:0019902

phosphatase binding

0.37

GO:0005759

mitochondrial matrix

sp|Q7Z5W3|BN3D2_HUMAN
Pre-miRNA 5'-monophosphate methyltransferase
Search

BCDIN3D

0.97	Pre-miRNA 5'-monophosphate methyltransferase

0.63	GO:0032259	methylation
0.63	GO:2000632	negative regulation of pre-miRNA processing
0.60	GO:0010586	miRNA metabolic process
0.48	GO:0009451	RNA modification
0.39	GO:0044260	cellular macromolecule metabolic process

0.63	GO:0008168	methyltransferase activity
0.46	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.63

GO:0008168

sp|Q7Z5Y6|BMP8A_HUMAN
Bone morphogenetic protein 8A
Search

0.85	Bone morphogenetic protein 5

0.74	GO:0010469	regulation of receptor activity
0.57	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.56	GO:0060395	SMAD protein signal transduction
0.55	GO:0030509	BMP signaling pathway
0.52	GO:0043408	regulation of MAPK cascade
0.52	GO:0048468	cell development
0.50	GO:0042981	regulation of apoptotic process
0.45	GO:0002024	diet induced thermogenesis
0.45	GO:0001503	ossification
0.45	GO:2000505	regulation of energy homeostasis

0.77	GO:0008083	growth factor activity
0.59	GO:0070700	BMP receptor binding
0.56	GO:0005160	transforming growth factor beta receptor binding
0.53	GO:0005125	cytokine activity
0.35	GO:0008410	CoA-transferase activity
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0008017	microtubule binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0003779	actin binding
0.32	GO:0030554	adenyl nucleotide binding

0.65	GO:0005576	extracellular region
0.34	GO:0031982	vesicle
0.32	GO:0005737	cytoplasm
0.32	GO:0005856	cytoskeleton
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

EC:2.8.3

GO:0008410

sp|Q7Z5Y7|KCD20_HUMAN
BTB/POZ domain-containing protein KCTD20
Search

KCTD20

0.95	Potassium channel tetramerisation domain containing 20

0.77

GO:0042327

positive regulation of phosphorylation

0.40

GO:0042802

identical protein binding

0.49

GO:0005737

cytoplasm

sp|Q7Z601|GP142_HUMAN
Probable G-protein coupled receptor 142
Search

GPR142

0.92	G-protein coupled receptor 142 short form

0.71

GO:0007186

G-protein coupled receptor signaling pathway

0.72

GO:0004930

G-protein coupled receptor activity

0.54	GO:0030054	cell junction
0.51	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q7Z602|GP141_HUMAN
Probable G-protein coupled receptor 141
Search

GPR141

0.97	G protein-coupled receptor 141-va

0.67

GO:0007186

G-protein coupled receptor signaling pathway

0.68

GO:0004930

G-protein coupled receptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q7Z614|SNX20_HUMAN
Sorting nexin-20
Search

SNX20

0.97	Sorting nexin-20

0.39

GO:0015031

protein transport

0.76	GO:0035091	phosphatidylinositol binding
0.35	GO:0005515	protein binding

0.53	GO:0005654	nucleoplasm
0.43	GO:0031901	early endosome membrane
0.36	GO:0005886	plasma membrane

sp|Q7Z624|CMKMT_HUMAN
Calmodulin-lysine N-methyltransferase
Search

CAMKMT

0.95	Calmodulin-lysine N-methyltransferase

0.61	GO:0018022	peptidyl-lysine methylation
0.53	GO:0007005	mitochondrion organization
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0006633	fatty acid biosynthetic process

0.72	GO:0018025	calmodulin-lysine N-methyltransferase activity
0.55	GO:0031072	heat shock protein binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.33	GO:0003677	DNA binding

0.47	GO:0005634	nucleus
0.45	GO:0043234	protein complex
0.42	GO:0005737	cytoplasm
0.36	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.72

EC:2.1.1.60

GO:0018025

sp|Q7Z628|ARHG8_HUMAN
Neuroepithelial cell-transforming gene 1 protein
Search

NET1

0.97	Neuroepithelial cell transforming gene 1

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.56	GO:0051451	myoblast migration
0.55	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.54	GO:0071479	cellular response to ionizing radiation
0.54	GO:0070301	cellular response to hydrogen peroxide
0.51	GO:0043065	positive regulation of apoptotic process
0.48	GO:2000055	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
0.47	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.55	GO:0017049	GTP-Rho binding
0.33	GO:0005509	calcium ion binding

0.45	GO:0005622	intracellular
0.41	GO:0043227	membrane-bounded organelle
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q7Z692|CEA19_HUMAN
Carcinoembryonic antigen-related cell adhesion molecule 19
Search

CEACAM19

0.97	Carcinoembryonic antigen-related cell adhesion molecule 19 transcript variant 3

0.37

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q7Z695|ADCK2_HUMAN
Uncharacterized aarF domain-containing protein kinase 2
Search

ADCK2

0.97	AarF domain-containing protein kinase 2

0.55	GO:0016310	phosphorylation
0.46	GO:0006464	cellular protein modification process

0.57	GO:0016301	kinase activity
0.47	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.45	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:2.7.1

GO:0016773

sp|Q7Z698|SPRE2_HUMAN
Sprouty-related, EVH1 domain-containing protein 2
Search

SPRED2

0.97	Sprouty-related, EVH1 domain-containing protein 2 isoform a

0.69	GO:0007275	multicellular organism development
0.69	GO:0009966	regulation of signal transduction
0.52	GO:0090311	regulation of protein deacetylation
0.51	GO:2001022	positive regulation of response to DNA damage stimulus
0.51	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.50	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.48	GO:0023056	positive regulation of signaling
0.48	GO:0010647	positive regulation of cell communication
0.47	GO:0023057	negative regulation of signaling
0.47	GO:0010648	negative regulation of cell communication

0.54	GO:0005173	stem cell factor receptor binding
0.51	GO:0030291	protein serine/threonine kinase inhibitor activity
0.49	GO:0019901	protein kinase binding

0.47	GO:0031410	cytoplasmic vesicle
0.41	GO:0005886	plasma membrane
0.40	GO:0012506	vesicle membrane
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0012505	endomembrane system
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z699|SPRE1_HUMAN
Sprouty-related, EVH1 domain-containing protein 1
Search

SPRED1

0.94	Sprouty-related, EVH1 domain-containing protein 1

0.69	GO:0009966	regulation of signal transduction
0.68	GO:0007275	multicellular organism development
0.60	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.60	GO:0090311	regulation of protein deacetylation
0.59	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.59	GO:2001022	positive regulation of response to DNA damage stimulus
0.57	GO:0006469	negative regulation of protein kinase activity
0.57	GO:0010923	negative regulation of phosphatase activity
0.55	GO:0071900	regulation of protein serine/threonine kinase activity
0.54	GO:0023056	positive regulation of signaling

0.62	GO:0005173	stem cell factor receptor binding
0.58	GO:0030291	protein serine/threonine kinase inhibitor activity
0.57	GO:0019902	phosphatase binding
0.56	GO:0019901	protein kinase binding

0.53	GO:0031410	cytoplasmic vesicle
0.50	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.38	GO:0005901	caveola
0.30	GO:0016021	integral component of membrane

sp|Q7Z6A9|BTLA_HUMAN
B- and T-lymphocyte attenuator
Search

BTLA

0.94	B and T lymphocyte associated

0.30

GO:0044425

membrane part

sp|Q7Z6B0|CCD91_HUMAN
Coiled-coil domain-containing protein 91
Search

CCDC91

0.97	Coiled-coil domain-containing protein 91

0.75	GO:0048193	Golgi vesicle transport
0.60	GO:0007041	lysosomal transport
0.57	GO:0016482	cytosolic transport
0.38	GO:0015031	protein transport

0.54

GO:0042802

identical protein binding

0.57	GO:0005802	trans-Golgi network
0.52	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q7Z6B7|SRGP1_HUMAN
SLIT-ROBO Rho GTPase-activating protein 1
Search

SRGAP1

0.88	SLIT-ROBO Rho GTPase-activating protein 1

0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.45	GO:0030336	negative regulation of cell migration
0.35	GO:0016477	cell migration
0.35	GO:0051056	regulation of small GTPase mediated signal transduction

0.75	GO:0005096	GTPase activator activity
0.46	GO:0048365	Rac GTPase binding

0.36

GO:0005737

cytoplasm

sp|Q7Z6E9|RBBP6_HUMAN
E3 ubiquitin-protein ligase RBBP6
Search

RBBP6

0.96	RB binding protein 6, ubiquitin ligase

0.73	GO:0016567	protein ubiquitination
0.70	GO:0006397	mRNA processing
0.70	GO:0035264	multicellular organism growth
0.70	GO:0061053	somite development
0.66	GO:0048568	embryonic organ development
0.65	GO:0006275	regulation of DNA replication
0.63	GO:0001701	in utero embryonic development
0.62	GO:0006511	ubiquitin-dependent protein catabolic process
0.56	GO:0006974	cellular response to DNA damage stimulus

0.76	GO:0061630	ubiquitin protein ligase activity
0.66	GO:0019901	protein kinase binding
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

0.67	GO:0016607	nuclear speck
0.66	GO:0005813	centrosome
0.52	GO:0043234	protein complex

sp|Q7Z6G3|NECA2_HUMAN
N-terminal EF-hand calcium-binding protein 2
Search

NECAB2

0.96	N-terminal EF-hand calcium-binding protein 2

0.58	GO:1904021	negative regulation of G-protein coupled receptor internalization
0.57	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.57	GO:1900451	positive regulation of glutamate receptor signaling pathway
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.50	GO:1905477	positive regulation of protein localization to membrane
0.40	GO:0042984	regulation of amyloid precursor protein biosynthetic process
0.35	GO:0019722	calcium-mediated signaling
0.35	GO:0030308	negative regulation of cell growth
0.35	GO:0043065	positive regulation of apoptotic process
0.34	GO:0019538	protein metabolic process

0.69	GO:0005509	calcium ion binding
0.59	GO:0031687	A2A adenosine receptor binding
0.58	GO:0031802	type 5 metabotropic glutamate receptor binding
0.38	GO:0042802	identical protein binding

0.41	GO:0005886	plasma membrane
0.40	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.40	GO:0000137	Golgi cis cisterna
0.39	GO:0030425	dendrite
0.39	GO:0030424	axon
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0044425	membrane part

sp|Q7Z6G8|ANS1B_HUMAN
Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Search

ANKS1B

0.85	Ankyrin repeat and sterile alpha motif domain-containing protein 1B

0.86

GO:1900383

regulation of synaptic plasticity by receptor localization to synapse

0.58

GO:0046875

ephrin receptor binding

0.48	GO:0005829	cytosol
0.43	GO:0043231	intracellular membrane-bounded organelle
0.43	GO:0005886	plasma membrane
0.42	GO:0043197	dendritic spine
0.42	GO:0014069	postsynaptic density
0.40	GO:0030054	cell junction
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

sp|Q7Z6I5|SPT12_HUMAN
Spermatogenesis-associated protein 12
Search

SPATA12

0.97	Spermatogenesis-associated protein 12

sp|Q7Z6I6|RHG30_HUMAN
Rho GTPase-activating protein 30
Search

ARHGAP30

0.97	Rho GTPase-activating protein 30

0.60	GO:0007165	signal transduction
0.51	GO:0043547	positive regulation of GTPase activity
0.36	GO:0051056	regulation of small GTPase mediated signal transduction
0.36	GO:0015031	protein transport

0.51	GO:0005096	GTPase activator activity
0.41	GO:0017124	SH3 domain binding
0.38	GO:0035091	phosphatidylinositol binding
0.36	GO:0046983	protein dimerization activity
0.33	GO:0019901	protein kinase binding

0.45	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0030027	lamellipodium
0.38	GO:0031410	cytoplasmic vesicle
0.35	GO:0005829	cytosol
0.35	GO:0005938	cell cortex
0.35	GO:0015629	actin cytoskeleton
0.32	GO:0012505	endomembrane system
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part

sp|Q7Z6I8|CE024_HUMAN
UPF0461 protein C5orf24
Search

0.36

GO:0006269

DNA replication, synthesis of RNA primer

0.57	GO:0004386	helicase activity
0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0003676	nucleic acid binding
0.43	GO:0005515	protein binding
0.36	GO:0003896	DNA primase activity
0.35	GO:0008270	zinc ion binding

0.36

GO:0003896

sp|Q7Z6J0|SH3R1_HUMAN
E3 ubiquitin-protein ligase SH3RF1
Search

SH3RF1

0.97	SH3 domain containing ring finger 1

0.83	GO:0046328	regulation of JNK cascade
0.78	GO:0006915	apoptotic process
0.62	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.62	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.40	GO:0016567	protein ubiquitination

0.51	GO:0046872	metal ion binding
0.50	GO:0016874	ligase activity
0.36	GO:0005515	protein binding
0.35	GO:0016740	transferase activity

0.52	GO:0005829	cytosol
0.43	GO:0030027	lamellipodium
0.42	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005794	Golgi apparatus

0.50

GO:0016874

sp|Q7Z6J2|GRASP_HUMAN
General receptor for phosphoinositides 1-associated scaffold protein
Search

CYTIP

0.92	Cytohesin-interacting protein (Fragment)

0.56	GO:0007165	signal transduction
0.54	GO:0030155	regulation of cell adhesion
0.41	GO:0008104	protein localization
0.41	GO:0071383	cellular response to steroid hormone stimulus
0.37	GO:0046907	intracellular transport
0.37	GO:0070727	cellular macromolecule localization
0.37	GO:0042886	amide transport
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription

0.49	GO:0030306	ADP-ribosylation factor binding
0.48	GO:0030165	PDZ domain binding
0.44	GO:0042802	identical protein binding
0.41	GO:0004879	nuclear receptor activity
0.41	GO:0003707	steroid hormone receptor activity
0.38	GO:0043565	sequence-specific DNA binding
0.37	GO:0008270	zinc ion binding

0.54	GO:0005938	cell cortex
0.51	GO:0005886	plasma membrane
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.43	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0098794	postsynapse
0.42	GO:0030054	cell junction
0.41	GO:0005641	nuclear envelope lumen
0.38	GO:0005769	early endosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z6J4|FGD2_HUMAN
FYVE, RhoGEF and PH domain-containing protein 2
Search

FGD2

0.92	FYVE, RhoGEF and PH domain-containing protein 2

0.76	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.53	GO:0046330	positive regulation of JNK cascade
0.50	GO:0046847	filopodium assembly
0.44	GO:0030036	actin cytoskeleton organization
0.43	GO:0008360	regulation of cell shape
0.40	GO:0030035	microspike assembly
0.39	GO:0030032	lamellipodium assembly
0.37	GO:0043065	positive regulation of apoptotic process
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.53	GO:0046872	metal ion binding
0.51	GO:1901981	phosphatidylinositol phosphate binding
0.33	GO:0003779	actin binding
0.33	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0001726	ruffle
0.51	GO:0005769	early endosome
0.49	GO:0030027	lamellipodium
0.44	GO:0005794	Golgi apparatus
0.43	GO:0005634	nucleus
0.39	GO:0030175	filopodium
0.37	GO:0031256	leading edge membrane
0.37	GO:0031253	cell projection membrane
0.37	GO:0005856	cytoskeleton
0.37	GO:0010008	endosome membrane

sp|Q7Z6J6|FRMD5_HUMAN
FERM domain-containing protein 5
Search

FRMD5

0.94	FERM domain-containing protein 5

0.52	GO:2000146	negative regulation of cell motility
0.51	GO:0030334	regulation of cell migration
0.50	GO:0045785	positive regulation of cell adhesion
0.45	GO:0031032	actomyosin structure organization

0.53	GO:0005178	integrin binding
0.53	GO:0008092	cytoskeletal protein binding
0.51	GO:0019901	protein kinase binding
0.43	GO:0005200	structural constituent of cytoskeleton

0.69	GO:0005856	cytoskeleton
0.51	GO:0005912	adherens junction
0.30	GO:0044425	membrane part

sp|Q7Z6J8|UBE3D_HUMAN
E3 ubiquitin-protein ligase E3D
Search

UBE3D

0.94	Ubiquitin protein ligase E3D

0.68	GO:0051865	protein autoubiquitination
0.67	GO:0006513	protein monoubiquitination
0.66	GO:0000209	protein polyubiquitination

0.69	GO:0044390	ubiquitin-like protein conjugating enzyme binding
0.66	GO:0030332	cyclin binding
0.62	GO:0061630	ubiquitin protein ligase activity
0.53	GO:0016874	ligase activity

0.62	GO:0000151	ubiquitin ligase complex
0.36	GO:0005737	cytoplasm

0.53

GO:0016874

sp|Q7Z6J9|SEN54_HUMAN
tRNA-splicing endonuclease subunit Sen54
Search

TSEN54

0.96	tRNA splicing endonuclease subunit 54

0.75	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.54	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.45	GO:0048854	brain morphogenesis

0.59

GO:0000213

tRNA-intron endonuclease activity

0.60

GO:0000214

tRNA-intron endonuclease complex

0.59

EC:3.1.27.9

GO:0000213

sp|Q7Z6K1|THAP5_HUMAN
THAP domain-containing protein 5
Search

THAP5

0.97	THAP domain-containing protein 5

0.59	GO:0045786	negative regulation of cell cycle
0.39	GO:0007049	cell cycle
0.37	GO:0097659	nucleic acid-templated transcription
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.62	GO:0002020	protease binding
0.55	GO:0003677	DNA binding
0.36	GO:0046872	metal ion binding

0.50

GO:0005634

nucleus

sp|Q7Z6K3|PTAR1_HUMAN
Protein prenyltransferase alpha subunit repeat-containing protein 1
Search

PTAR1

0.96	Protein prenyltransferase alpha subunit repeat-containing protein 1-A

0.81	GO:0097354	prenylation
0.60	GO:0006464	cellular protein modification process

0.82

GO:0008318

protein prenyltransferase activity

0.44	GO:1990234	transferase complex
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.5.1

GO:0008318

sp|Q7Z6K4|NRARP_HUMAN
Notch-regulated ankyrin repeat-containing protein
Search

NRARP

0.52	Notch-regulated ankyrin repeat-containing protein A

0.82	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.78	GO:0001569	branching involved in blood vessel morphogenesis
0.72	GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis
0.71	GO:0060828	regulation of canonical Wnt signaling pathway
0.70	GO:0001938	positive regulation of endothelial cell proliferation
0.70	GO:0032525	somite rostral/caudal axis specification
0.69	GO:0007219	Notch signaling pathway
0.69	GO:0022407	regulation of cell-cell adhesion
0.67	GO:0030177	positive regulation of Wnt signaling pathway
0.67	GO:0045620	negative regulation of lymphocyte differentiation

0.49	GO:0019901	protein kinase binding
0.34	GO:0003677	DNA binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005913	cell-cell adherens junction
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z6K5|ARPIN_HUMAN
Arpin
Search

ARPIN

0.97	Actin-related protein 2/3 complex inhibitor

0.85	GO:0051126	negative regulation of actin nucleation
0.53	GO:0033058	directional locomotion
0.49	GO:0030336	negative regulation of cell migration
0.47	GO:2000393	negative regulation of lamellipodium morphogenesis
0.46	GO:0006886	intracellular protein transport
0.46	GO:0016192	vesicle-mediated transport

0.34	GO:0005515	protein binding
0.33	GO:0008565	protein transporter activity

0.53	GO:0030027	lamellipodium
0.48	GO:0030117	membrane coat
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|Q7Z6L0|PRRT2_HUMAN
Proline-rich transmembrane protein 2
Search

PRRT2

0.96	Proline-rich transmembrane protein 2

0.69	GO:0009607	response to biotic stimulus
0.68	GO:1905512	regulation of short-term synaptic potentiation
0.65	GO:0035544	negative regulation of SNARE complex assembly
0.65	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane
0.47	GO:0050884	neuromuscular process controlling posture

0.64	GO:0017075	syntaxin-1 binding
0.41	GO:0017124	SH3 domain binding
0.34	GO:0003676	nucleic acid binding

0.62	GO:0042734	presynaptic membrane
0.61	GO:0043679	axon terminus
0.60	GO:0008021	synaptic vesicle
0.45	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|Q7Z6L1|TCPR1_HUMAN
Tectonin beta-propeller repeat-containing protein 1
Search

TECPR1

0.91	Tectonin beta-propeller repeat-containing protein 1

0.58

GO:0097352

autophagosome maturation

0.55	GO:0032266	phosphatidylinositol-3-phosphate binding
0.35	GO:0005515	protein binding

0.58	GO:0000421	autophagosome membrane
0.55	GO:0005765	lysosomal membrane
0.47	GO:0005654	nucleoplasm
0.44	GO:0031410	cytoplasmic vesicle
0.30	GO:0044425	membrane part

sp|Q7Z6M1|RABEK_HUMAN
Rab9 effector protein with kelch motifs
Search

RABEPK

0.97	Rab9 effector protein with kelch motifs

0.56	GO:0006904	vesicle docking involved in exocytosis
0.51	GO:0006898	receptor-mediated endocytosis

0.76	GO:0010008	endosome membrane
0.59	GO:0032588	trans-Golgi network membrane
0.54	GO:0030133	transport vesicle
0.50	GO:0005829	cytosol

sp|Q7Z6M2|FBX33_HUMAN
F-box only protein 33
Search

FBXO33

0.97	F-box only protein 33

0.66

GO:0016567

protein ubiquitination

0.50	GO:0005515	protein binding
0.42	GO:0003677	DNA binding

0.45	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q7Z6M3|MILR1_HUMAN
Allergin-1
Search

MILR1

0.97	Mast cell immunoglobulin like receptor 1

0.86	GO:0033004	negative regulation of mast cell activation
0.86	GO:0043303	mast cell degranulation

0.86	GO:0042629	mast cell granule
0.38	GO:0005887	integral component of plasma membrane

sp|Q7Z6M4|MTEF4_HUMAN
Transcription termination factor 4, mitochondrial
Search

MTERF4

0.97	Mitochondrial transcription termination factor 4

0.61	GO:0006390	mitochondrial transcription
0.57	GO:0043010	camera-type eye development
0.56	GO:0007507	heart development
0.56	GO:0042255	ribosome assembly
0.56	GO:0006626	protein targeting to mitochondrion
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.46	GO:0008380	RNA splicing
0.38	GO:0006364	rRNA processing

0.69	GO:0003690	double-stranded DNA binding
0.51	GO:0019843	rRNA binding
0.49	GO:0003727	single-stranded RNA binding
0.35	GO:0004672	protein kinase activity
0.35	GO:0005515	protein binding
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005762	mitochondrial large ribosomal subunit
0.52	GO:0005829	cytosol
0.34	GO:0005730	nucleolus
0.34	GO:0005801	cis-Golgi network
0.33	GO:0016456	X chromosome located dosage compensation complex, transcription activating
0.32	GO:0044545	NSL complex
0.32	GO:0005705	polytene chromosome interband
0.32	GO:0072487	MSL complex
0.32	GO:0012505	endomembrane system
0.32	GO:0005854	nascent polypeptide-associated complex

0.32

GO:0004222

sp|Q7Z6P3|RAB44_HUMAN
Ras-related protein Rab-44
Search

RAB44

0.78	RAB44, member RAS oncogene family

0.40	GO:0048227	plasma membrane to endosome transport
0.40	GO:0043312	neutrophil degranulation
0.38	GO:0030100	regulation of endocytosis
0.35	GO:0007050	cell cycle arrest
0.35	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.34	GO:0001702	gastrulation with mouth forming second
0.34	GO:0001525	angiogenesis
0.34	GO:0098609	cell-cell adhesion
0.34	GO:0007165	signal transduction
0.34	GO:0034765	regulation of ion transmembrane transport

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.41	GO:0005509	calcium ion binding
0.40	GO:0019003	GDP binding
0.35	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.34	GO:0038023	signaling receptor activity
0.34	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0099600	transmembrane receptor activity
0.33	GO:0004673	protein histidine kinase activity
0.33	GO:0004767	sphingomyelin phosphodiesterase activity

0.42	GO:0031410	cytoplasmic vesicle
0.40	GO:0012505	endomembrane system
0.40	GO:0005766	primary lysosome
0.39	GO:0005811	lipid droplet
0.38	GO:0005765	lysosomal membrane
0.38	GO:0012506	vesicle membrane
0.36	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.33	GO:0031225	anchored component of membrane
0.33	GO:0098793	presynapse

0.33	EC:2.7.13.3	GO:0004673
0.33	KEGG:R02541	GO:0004767

sp|Q7Z6R9|AP2D_HUMAN
Transcription factor AP-2-delta
Search

TFAP2D

0.97	Transcription factor AP-2 delta (activating enhancer binding protein 2 delta)

0.63	GO:0061379	inferior colliculus development
0.58	GO:0043524	negative regulation of neuron apoptotic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:0042127	regulation of cell proliferation
0.38	GO:0035213	clypeo-labral disc development
0.38	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.38	GO:0002121	inter-male aggressive behavior

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0000987	proximal promoter sequence-specific DNA binding
0.33	GO:0050662	coenzyme binding
0.30	GO:0003824	catalytic activity

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q7Z6V5|ADAT2_HUMAN
tRNA-specific adenosine deaminase 2
Search

ADAT2

0.94	tRNA-specific adenosine deaminase 2

0.65

GO:0002100

tRNA wobble adenosine to inosine editing

0.66	GO:0008251	tRNA-specific adenosine deaminase activity
0.62	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.52	GO:0052718	tRNA-specific adenosine-34 deaminase complex
0.34	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.66

EC:3.5.4

GO:0008251

sp|Q7Z6W1|TMCO2_HUMAN
Transmembrane and coiled-coil domain-containing protein 2
Search

0.33

GO:0003676

nucleic acid binding

0.38	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q7Z6W7|DNJB7_HUMAN
DnaJ homolog subfamily B member 7
Search

DNAJB6

0.79	DnaJ like protein subfamily B member 7

0.62	GO:0090084	negative regulation of inclusion body assembly
0.60	GO:0045109	intermediate filament organization
0.59	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:0032781	positive regulation of ATPase activity
0.55	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development
0.54	GO:0060710	chorio-allantoic fusion
0.53	GO:0060717	chorion development
0.53	GO:0032880	regulation of protein localization
0.50	GO:0006457	protein folding
0.49	GO:0030198	extracellular matrix organization

0.72	GO:0051087	chaperone binding
0.57	GO:0001671	ATPase activator activity
0.55	GO:0031072	heat shock protein binding
0.52	GO:0051082	unfolded protein binding
0.41	GO:0042802	identical protein binding
0.40	GO:0003677	DNA binding
0.38	GO:0044183	protein binding involved in protein folding
0.34	GO:0003735	structural constituent of ribosome
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.62	GO:0030018	Z disc
0.61	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.34	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|Q7Z6Z6|PLPL5_HUMAN
Patatin-like phospholipase domain-containing protein 5
Search

0.88	Patatin like phospholipase domain containing 5

0.70	GO:0016042	lipid catabolic process
0.70	GO:0010898	positive regulation of triglyceride catabolic process
0.55	GO:0006641	triglyceride metabolic process
0.51	GO:0034389	lipid particle organization
0.51	GO:0010891	negative regulation of sequestering of triglyceride
0.50	GO:0055088	lipid homeostasis
0.47	GO:0019915	lipid storage
0.46	GO:0044248	cellular catabolic process
0.42	GO:0036155	acylglycerol acyl-chain remodeling
0.39	GO:0046463	acylglycerol biosynthetic process

0.67	GO:0004806	triglyceride lipase activity
0.41	GO:0051265	diolein transacylation activity
0.41	GO:0051264	mono-olein transacylation activity
0.41	GO:0035727	lysophosphatidic acid binding
0.41	GO:0036042	long-chain fatty acyl-CoA binding
0.39	GO:0004623	phospholipase A2 activity
0.39	GO:0042171	lysophosphatidic acid acyltransferase activity
0.34	GO:0005515	protein binding

0.55	GO:0005811	lipid droplet
0.43	GO:0005829	cytosol
0.43	GO:0005654	nucleoplasm
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005886	plasma membrane
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.67

EC:3.1.1.3

GO:0004806

sp|Q7Z6Z7|HUWE1_HUMAN
E3 ubiquitin-protein ligase HUWE1
Search

HUWE1

0.48	HECT, UBA and WWE domain containing 1

0.72	GO:0016567	protein ubiquitination
0.55	GO:1903955	positive regulation of protein targeting to mitochondrion
0.50	GO:0016570	histone modification
0.49	GO:0006284	base-excision repair
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0043312	neutrophil degranulation
0.38	GO:0030154	cell differentiation
0.32	GO:0006355	regulation of transcription, DNA-templated

0.73	GO:0004842	ubiquitin-protein transferase activity
0.49	GO:0016874	ligase activity
0.47	GO:0061659	ubiquitin-like protein ligase activity
0.46	GO:0008270	zinc ion binding
0.35	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.38	GO:1904813	ficolin-1-rich granule lumen
0.38	GO:0034774	secretory granule lumen
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.49	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q7Z713|ANR37_HUMAN
Ankyrin repeat domain-containing protein 37
Search

ANKRD37

0.97	LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 37

0.42	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.36	GO:0006508	proteolysis

0.42	GO:0071567	UFM1 hydrolase activity
0.39	GO:0016790	thiolester hydrolase activity
0.36	GO:0005515	protein binding

0.68	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.60	GO:0005739	mitochondrion
0.38	GO:0005783	endoplasmic reticulum

0.39

EC:3.1.2

GO:0016790

sp|Q7Z736|PKHH3_HUMAN
Pleckstrin homology domain-containing family H member 3
Search

PLEKHH3

0.80	Unconventional myosin-X

0.57	GO:0007165	signal transduction
0.49	GO:0007018	microtubule-based movement
0.37	GO:0051489	regulation of filopodium assembly
0.36	GO:0022409	positive regulation of cell-cell adhesion
0.35	GO:0008360	regulation of cell shape

0.49	GO:0003777	microtubule motor activity
0.49	GO:0008017	microtubule binding
0.49	GO:0003779	actin binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0030507	spectrin binding
0.32	GO:0003676	nucleic acid binding

0.68	GO:0005856	cytoskeleton
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005615	extracellular space
0.36	GO:0030175	filopodium
0.36	GO:0043025	neuronal cell body
0.36	GO:0043005	neuron projection
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus

sp|Q7Z739|YTHD3_HUMAN
YTH domain-containing family protein 3
Search

YTHDF3

0.97	LOW QUALITY PROTEIN: YTH domain-containing family protein 3

0.40	GO:0061157	mRNA destabilization
0.38	GO:0045727	positive regulation of translation
0.37	GO:0006446	regulation of translational initiation

0.58	GO:0003723	RNA binding
0.38	GO:0043022	ribosome binding
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.36

GO:0005829

cytosol

sp|Q7Z745|MRO2B_HUMAN
Maestro heat-like repeat-containing protein family member 2B
Search

MROH2B

0.97	LOW QUALITY PROTEIN: maestro heat-like repeat-containing protein family member 2B

0.86	GO:0010737	protein kinase A signaling
0.46	GO:0007283	spermatogenesis
0.43	GO:0030154	cell differentiation

0.37

GO:0005515

protein binding

0.86	GO:0097225	sperm midpiece
0.84	GO:0001669	acrosomal vesicle

sp|Q7Z769|S35E3_HUMAN
Solute carrier family 35 member E3
Search

SLC35E3

0.96	Siah E3 ubiquitin protein ligase family member 3

0.30

GO:0044425

membrane part

sp|Q7Z794|K2C1B_HUMAN
Keratin, type II cytoskeletal 1b
Search

0.94	Keratin, type II cytoskeletal 2 epidermal

0.53	GO:0043588	skin development
0.52	GO:0018149	peptide cross-linking
0.48	GO:0001867	complement activation, lectin pathway
0.48	GO:0033561	regulation of water loss via skin
0.48	GO:0032980	keratinocyte activation
0.47	GO:0045104	intermediate filament cytoskeleton organization
0.47	GO:0050728	negative regulation of inflammatory response
0.47	GO:0008544	epidermis development
0.47	GO:0051546	keratinocyte migration
0.46	GO:0043616	keratinocyte proliferation

0.62	GO:0005198	structural molecule activity
0.42	GO:0030246	carbohydrate binding
0.41	GO:0005515	protein binding
0.35	GO:0044877	macromolecular complex binding
0.33	GO:0004872	receptor activity

0.83	GO:0045095	keratin filament
0.53	GO:0001533	cornified envelope
0.40	GO:0070062	extracellular exosome
0.36	GO:0072562	blood microparticle
0.36	GO:0031012	extracellular matrix
0.36	GO:0005829	cytosol
0.35	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.33	GO:0036338	viral membrane

sp|Q7Z7A1|CNTRL_HUMAN
Centriolin
Search

CNTRL

0.97	Centriolin

0.75	GO:0000278	mitotic cell cycle
0.67	GO:0051301	cell division
0.41	GO:0060976	coronary vasculature development
0.41	GO:0035904	aorta development
0.40	GO:0003281	ventricular septum development
0.38	GO:0097711	ciliary basal body-plasma membrane docking
0.37	GO:0044839	cell cycle G2/M phase transition
0.36	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.36	GO:0018108	peptidyl-tyrosine phosphorylation

0.36	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005515	protein binding

0.61	GO:0120103	centriolar subdistal appendage
0.55	GO:0005813	centrosome
0.49	GO:0005829	cytosol
0.41	GO:0097431	mitotic spindle pole
0.39	GO:0090543	Flemming body
0.39	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

0.36

EC:2.7.10

GO:0004713

sp|Q7Z7A3|CTU1_HUMAN
Cytoplasmic tRNA 2-thiolation protein 1
Search

NCS6

0.73	Cytosolic thiouridylase subunit 1

0.78	GO:0034227	tRNA thio-modification
0.78	GO:0032447	protein urmylation
0.76	GO:0002098	tRNA wobble uridine modification
0.34	GO:0006508	proteolysis
0.34	GO:0040025	vulval development
0.34	GO:0048599	oocyte development
0.34	GO:0007283	spermatogenesis
0.34	GO:0048598	embryonic morphogenesis
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process

0.69	GO:0000049	tRNA binding
0.59	GO:0016779	nucleotidyltransferase activity
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0016783	sulfurtransferase activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0002144	cytosolic tRNA wobble base thiouridylase complex
0.42	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.59

GO:0016779

sp|Q7Z7A4|PXK_HUMAN
PX domain-containing protein kinase-like protein
Search

PXK

0.96	PX domain containing serine/threonine kinase like

0.62	GO:0006468	protein phosphorylation
0.52	GO:0006954	inflammatory response
0.38	GO:0043271	negative regulation of ion transport
0.38	GO:0050804	modulation of chemical synaptic transmission
0.38	GO:0032780	negative regulation of ATPase activity
0.34	GO:0090501	RNA phosphodiester bond hydrolysis
0.34	GO:0008033	tRNA processing

0.75	GO:0035091	phosphatidylinositol binding
0.67	GO:0003779	actin binding
0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008022	protein C-terminus binding
0.34	GO:0004540	ribonuclease activity

0.51	GO:0005815	microtubule organizing center
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.35	GO:0005634	nucleus
0.34	GO:0043234	protein complex

sp|Q7Z7B0|FLIP1_HUMAN
Filamin-A-interacting protein 1
Search

FILIP1

0.92	Filamin-A-interacting protein 1

0.33	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0022900	electron transport chain

0.33	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity

0.68	GO:0015629	actin cytoskeleton
0.68	GO:0005730	nucleolus
0.52	GO:0005886	plasma membrane
0.42	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.9

GO:0016675

sp|Q7Z7B1|PIGW_HUMAN
Phosphatidylinositol-glycan biosynthesis class W protein
Search

PIGW

0.91	Phosphatidylinositol-glycan biosynthesis class W protein (Fragment)

0.78	GO:0006506	GPI anchor biosynthetic process
0.56	GO:0072659	protein localization to plasma membrane
0.33	GO:0006486	protein glycosylation
0.32	GO:0006897	endocytosis

0.63	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0008378	galactosyltransferase activity
0.32	GO:0004040	amidase activity

0.66	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0016746

sp|Q7Z7B7|DB132_HUMAN
Beta-defensin 132
Search

DEFB132

0.64	Beta-defensin

0.79	GO:0045087	innate immune response
0.77	GO:0042742	defense response to bacterium
0.68	GO:0031640	killing of cells of other organism

0.78	GO:0061827	sperm head
0.66	GO:0005576	extracellular region
0.51	GO:0009986	cell surface

sp|Q7Z7B8|DB128_HUMAN
Beta-defensin 128
Search

DEFB128

0.63	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium
0.66	GO:0031640	killing of cells of other organism

0.66	GO:0005576	extracellular region
0.50	GO:0009986	cell surface

sp|Q7Z7C7|STRA8_HUMAN
Stimulated by retinoic acid gene 8 protein homolog
Search

STRA8

0.95	LOW QUALITY PROTEIN: stimulated by retinoic acid gene 8 protein homolog

0.85	GO:0071300	cellular response to retinoic acid
0.78	GO:0051321	meiotic cell cycle
0.72	GO:0048133	male germ-line stem cell asymmetric division
0.61	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0048477	oogenesis
0.38	GO:0006260	DNA replication
0.37	GO:0006351	transcription, DNA-templated

0.64

GO:0046983

protein dimerization activity

0.52	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm

sp|Q7Z7C8|TAF8_HUMAN
Transcription initiation factor TFIID subunit 8
Search

TAF8

0.93	Transcription initiation factor TFIID subunit 8

0.59	GO:0006413	translational initiation
0.55	GO:0051457	maintenance of protein location in nucleus
0.54	GO:0045598	regulation of fat cell differentiation
0.53	GO:0001833	inner cell mass cell proliferation
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0006030	chitin metabolic process
0.35	GO:0016073	snRNA metabolic process
0.35	GO:0005975	carbohydrate metabolic process

0.70	GO:0046982	protein heterodimerization activity
0.59	GO:0003743	translation initiation factor activity
0.37	GO:0008061	chitin binding
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.74	GO:0005669	transcription factor TFIID complex
0.52	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.2.1

GO:0004553

sp|Q7Z7D3|VTCN1_HUMAN
V-set domain-containing T-cell activation inhibitor 1
Search

VTCN1

0.97	V-set domain-containing T-cell activation inhibitor 1

0.71	GO:1900042	positive regulation of interleukin-2 secretion
0.70	GO:0072643	interferon-gamma secretion
0.70	GO:0072602	interleukin-4 secretion
0.68	GO:0001562	response to protozoan
0.67	GO:0042130	negative regulation of T cell proliferation
0.66	GO:0042102	positive regulation of T cell proliferation
0.61	GO:0043066	negative regulation of apoptotic process
0.44	GO:0002250	adaptive immune response

0.57

GO:0005102

receptor binding

0.64	GO:0009897	external side of plasma membrane
0.40	GO:0031225	anchored component of membrane
0.30	GO:0016021	integral component of membrane

sp|Q7Z7E8|UB2Q1_HUMAN
Ubiquitin-conjugating enzyme E2 Q1
Search

UBE2Q1

0.90	Ubiquitin-conjugating enzyme E2Q family member 2

0.85	GO:0070459	prolactin secretion
0.82	GO:0001967	suckling behavior
0.81	GO:0007617	mating behavior
0.80	GO:0007566	embryo implantation
0.78	GO:0009566	fertilization
0.74	GO:0061458	reproductive system development
0.72	GO:0016567	protein ubiquitination

0.83	GO:0061631	ubiquitin conjugating enzyme activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005515	protein binding

0.45	GO:0030175	filopodium
0.42	GO:0005829	cytosol
0.39	GO:0005634	nucleus

sp|Q7Z7F0|K0907_HUMAN
UPF0469 protein KIAA0907
Search

KHDC4

0.97	KH homology domain-containing protein 4

0.77

GO:0006376

mRNA splice site selection

0.59	GO:0003723	RNA binding
0.52	GO:0005515	protein binding

0.71	GO:0005681	spliceosomal complex
0.50	GO:0019013	viral nucleocapsid
0.47	GO:0005737	cytoplasm

sp|Q7Z7F7|RM55_HUMAN
39S ribosomal protein L55, mitochondrial
Search

MRPL55

0.97	Mitochondrial ribosomal protein L55

0.39	GO:0070126	mitochondrial translational termination
0.38	GO:0070125	mitochondrial translational elongation
0.34	GO:0016310	phosphorylation

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0016301	kinase activity

0.82	GO:0005762	mitochondrial large ribosomal subunit
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane

sp|Q7Z7G0|TARSH_HUMAN
Target of Nesh-SH3
Search

ABI3BP

0.79	ABI family, member 3 (NESH) binding protein b

0.84	GO:0010811	positive regulation of cell-substrate adhesion
0.80	GO:0030198	extracellular matrix organization

0.83	GO:0005518	collagen binding
0.82	GO:0008201	heparin binding

0.86	GO:0005614	interstitial matrix
0.70	GO:0005615	extracellular space

sp|Q7Z7G1|CLNK_HUMAN
Cytokine-dependent hematopoietic cell linker
Search

CLNK

0.97	Cytokine-dependent hematopoietic cell linker

0.70	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.59	GO:0035556	intracellular signal transduction
0.58	GO:0006955	immune response
0.50	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.41	GO:0009967	positive regulation of signal transduction
0.40	GO:0046856	phosphatidylinositol dephosphorylation
0.37	GO:0042127	regulation of cell proliferation
0.37	GO:0045659	negative regulation of neutrophil differentiation
0.37	GO:0016310	phosphorylation
0.37	GO:0045409	negative regulation of interleukin-6 biosynthetic process

0.51	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.43	GO:0005070	SH3/SH2 adaptor activity
0.37	GO:0051425	PTB domain binding
0.37	GO:0016301	kinase activity
0.37	GO:0004445	inositol-polyphosphate 5-phosphatase activity
0.36	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity
0.36	GO:0019900	kinase binding
0.35	GO:0017124	SH3 domain binding
0.33	GO:0043560	insulin receptor substrate binding
0.33	GO:0046872	metal ion binding

0.49	GO:0005942	phosphatidylinositol 3-kinase complex
0.44	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.37

EC:3.1.3.56

GO:0004445

sp|Q7Z7G2|CPLX4_HUMAN
Complexin-4
Search

CPLX4

0.97	LOW QUALITY PROTEIN: complexin-4

0.76	GO:0006836	neurotransmitter transport
0.64	GO:0046928	regulation of neurotransmitter secretion
0.50	GO:0030073	insulin secretion
0.49	GO:0017156	calcium ion regulated exocytosis
0.48	GO:0097480	establishment of synaptic vesicle localization
0.48	GO:0099504	synaptic vesicle cycle
0.48	GO:0099003	vesicle-mediated transport in synapse
0.48	GO:0099643	signal release from synapse
0.48	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.44	GO:0046907	intracellular transport

0.84	GO:0019905	syntaxin binding
0.47	GO:0005326	neurotransmitter transporter activity
0.35	GO:0005537	mannose binding
0.33	GO:0003677	DNA binding

0.58	GO:0045202	synapse
0.48	GO:0097458	neuron part
0.43	GO:0005829	cytosol
0.39	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0005886	plasma membrane
0.38	GO:0030054	cell junction
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q7Z7G8|VP13B_HUMAN
Vacuolar protein sorting-associated protein 13B
Search

VPS13B

0.84	Vacuolar protein sorting-associated protein 13B

0.30	GO:0045184	establishment of protein localization
0.30	GO:0042886	amide transport
0.30	GO:0071702	organic substance transport

0.30

GO:0044425

membrane part

sp|Q7Z7H3|CATIP_HUMAN
Ciliogenesis-associated TTC17-interacting protein
Search

CATIP

0.97	ciliogenesis-associated TTC17-interacting protein isoform X1

0.83	GO:0030041	actin filament polymerization
0.78	GO:0044782	cilium organization
0.47	GO:0061371	determination of heart left/right asymmetry
0.45	GO:0120031	plasma membrane bounded cell projection assembly
0.43	GO:0070925	organelle assembly
0.39	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

0.39	GO:0004416	hydroxyacylglutathione hydrolase activity
0.38	GO:0005515	protein binding

0.71	GO:0015629	actin cytoskeleton
0.60	GO:0005634	nucleus
0.54	GO:0005886	plasma membrane
0.48	GO:0005737	cytoplasm

0.39

EC:3.1.2.6

GO:0004416

sp|Q7Z7H5|TMED4_HUMAN
Transmembrane emp24 domain-containing protein 4
Search

TMED4

0.92	Endoplasmic reticulum stress-response protein 25

0.52	GO:0048205	COPI coating of Golgi vesicle
0.48	GO:0007030	Golgi organization
0.46	GO:0010638	positive regulation of organelle organization
0.37	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.37	GO:0033036	macromolecule localization
0.37	GO:0042886	amide transport
0.36	GO:0071702	organic substance transport
0.36	GO:0034498	early endosome to Golgi transport
0.34	GO:0007165	signal transduction
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER

0.48	GO:0019905	syntaxin binding
0.35	GO:0004871	signal transducer activity
0.34	GO:0005319	lipid transporter activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.67	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.45	GO:0000139	Golgi membrane
0.39	GO:0070062	extracellular exosome
0.35	GO:0030133	transport vesicle
0.34	GO:0030136	clathrin-coated vesicle
0.34	GO:0099503	secretory vesicle
0.34	GO:0005798	Golgi-associated vesicle
0.30	GO:0016021	integral component of membrane

sp|Q7Z7H8|RM10_HUMAN
39S ribosomal protein L10, mitochondrial
Search

MRPL10

0.97	Mitochondrial ribosomal protein L10

0.64	GO:0042254	ribosome biogenesis
0.49	GO:0032543	mitochondrial translation
0.35	GO:0006415	translational termination
0.35	GO:0006414	translational elongation
0.35	GO:0006869	lipid transport
0.33	GO:0006508	proteolysis

0.43	GO:0003735	structural constituent of ribosome
0.35	GO:0016805	dipeptidase activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.59	GO:0005762	mitochondrial large ribosomal subunit
0.51	GO:0005654	nucleoplasm
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

0.35

EC:3.4.13

GO:0016805

sp|Q7Z7J5|DPPA2_HUMAN
Developmental pluripotency-associated protein 2
Search

DPPA2

0.97	Developmental pluripotency-associated protein 2

0.52	GO:0060484	lung-associated mesenchyme development
0.47	GO:0019827	stem cell population maintenance
0.46	GO:2000648	positive regulation of stem cell proliferation
0.45	GO:0031060	regulation of histone methylation
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:0010468	regulation of gene expression

0.43	GO:0003682	chromatin binding
0.41	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part

sp|Q7Z7J7|LHPL4_HUMAN
Lipoma HMGIC fusion partner-like 4 protein
Search

LHFPL4

0.96	LHFPL tetraspan subfamily member 4

0.34

GO:0050974

detection of mechanical stimulus involved in sensory perception

0.30

GO:0031224

intrinsic component of membrane

sp|Q7Z7J9|CK2N1_HUMAN
Calcium/calmodulin-dependent protein kinase II inhibitor 1
Search

CAMK2N2

0.95	Calcium/calmodulin dependent protein kinase II inhibitor 1

0.81	GO:0006469	negative regulation of protein kinase activity
0.51	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.49	GO:1904029	regulation of cyclin-dependent protein kinase activity
0.49	GO:0008285	negative regulation of cell proliferation
0.48	GO:0016310	phosphorylation
0.48	GO:0045786	negative regulation of cell cycle
0.47	GO:0045861	negative regulation of proteolysis
0.46	GO:0010628	positive regulation of gene expression
0.35	GO:0007268	chemical synaptic transmission
0.35	GO:0048167	regulation of synaptic plasticity

0.83	GO:0004860	protein kinase inhibitor activity
0.64	GO:0010858	calcium-dependent protein kinase regulator activity
0.54	GO:0019901	protein kinase binding
0.50	GO:0016301	kinase activity

0.50	GO:0014069	postsynaptic density
0.48	GO:0005813	centrosome
0.42	GO:0005634	nucleus
0.40	GO:0045211	postsynaptic membrane
0.40	GO:0043005	neuron projection
0.39	GO:0030054	cell junction
0.39	GO:0043025	neuronal cell body
0.38	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005829	cytosol

sp|Q7Z7K0|COXM1_HUMAN
COX assembly mitochondrial protein homolog
Search

CMC1

0.66	COX assembly mitochondrial protein homolog

0.35	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.34	GO:0015991	ATP hydrolysis coupled proton transport
0.32	GO:0007165	signal transduction

0.35	GO:0046872	metal ion binding
0.34	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.33	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0004888	transmembrane signaling receptor activity

0.60	GO:0005739	mitochondrion
0.35	GO:0031970	organelle envelope lumen
0.34	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain
0.30	GO:0016021	integral component of membrane

sp|Q7Z7K2|ZN467_HUMAN
Zinc finger protein 467
Search

ZNF467

0.77	Zinc finger protein 467

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:1901216	positive regulation of neuron death
0.43	GO:0006366	transcription by RNA polymerase II
0.42	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.48	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.46	GO:0046872	metal ion binding
0.44	GO:0031625	ubiquitin protein ligase binding

0.48	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm

sp|Q7Z7K6|CENPV_HUMAN
Centromere protein V
Search

CENPV

0.86	Centromere protein V

0.56	GO:0031508	pericentric heterochromatin assembly
0.52	GO:0032467	positive regulation of cytokinesis
0.51	GO:0001667	ameboidal-type cell migration
0.49	GO:0033044	regulation of chromosome organization
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.30	GO:0008152	metabolic process

0.71

GO:0016846

carbon-sulfur lyase activity

0.52	GO:0051233	spindle midzone
0.50	GO:0000776	kinetochore
0.43	GO:0005634	nucleus
0.38	GO:0000779	condensed chromosome, centromeric region
0.33	GO:0005737	cytoplasm

0.71

EC:4.4

GO:0016846

sp|Q7Z7L1|SLN11_HUMAN
Schlafen family member 11
Search

0.97	Schlafen family member 10 homologue, CAST/EiJ strain specific

0.61	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.56	GO:0051607	defense response to virus
0.46	GO:0036345	platelet maturation
0.41	GO:0016075	rRNA catabolic process
0.41	GO:0006402	mRNA catabolic process
0.40	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0000049	tRNA binding
0.40	GO:0043022	ribosome binding
0.40	GO:0004521	endoribonuclease activity

0.54	GO:0005634	nucleus
0.47	GO:0016235	aggresome
0.42	GO:0005829	cytosol
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q7Z7L7|ZER1_HUMAN
Protein zer-1 homolog
Search

ZER1

0.97	Zyg-11 protein B

0.80	GO:0051438	regulation of ubiquitin-protein transferase activity
0.71	GO:0016567	protein ubiquitination
0.39	GO:0006468	protein phosphorylation

0.72	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0004674	protein serine/threonine kinase activity

0.85	GO:0031462	Cul2-RING ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:2.7.11	GO:0004674
0.72	KEGG:R03876	GO:0004842

sp|Q7Z7L8|CK096_HUMAN
Uncharacterized protein C11orf96
Search

0.54	GO:0035552	oxidative single-stranded DNA demethylation
0.52	GO:0006307	DNA dealkylation involved in DNA repair
0.49	GO:0000160	phosphorelay signal transduction system
0.39	GO:0034220	ion transmembrane transport

0.54	GO:0042302	structural constituent of cuticle
0.48	GO:0051213	dioxygenase activity
0.47	GO:0003779	actin binding
0.42	GO:0005216	ion channel activity

0.45	GO:0005581	collagen trimer
0.39	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q7Z7L9|ZSCA2_HUMAN
Zinc finger and SCAN domain-containing protein 2
Search

0.55	Zinc finger and SCAN domain-containing protein 2

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.40	GO:0006351	transcription, DNA-templated
0.34	GO:0044789	modulation by host of viral release from host cell
0.34	GO:1902188	positive regulation of viral release from host cell
0.34	GO:0044794	positive regulation by host of viral process
0.33	GO:0032259	methylation
0.30	GO:0030154	cell differentiation
0.30	GO:0048232	male gamete generation

0.50	GO:0003700	DNA binding transcription factor activity
0.49	GO:0003676	nucleic acid binding
0.47	GO:0046872	metal ion binding
0.33	GO:0008168	methyltransferase activity

0.48

GO:0005634

nucleus

0.33

GO:0008168

sp|Q7Z7M0|MEGF8_HUMAN
Multiple epidermal growth factor-like domains protein 8
Search

MEGF8

0.68	Multiple EGF like domains 8

0.66	GO:0060972	left/right pattern formation
0.66	GO:0097155	fasciculation of sensory neuron axon
0.65	GO:0048842	positive regulation of axon extension involved in axon guidance
0.65	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.64	GO:0071907	determination of digestive tract left/right asymmetry
0.63	GO:0042074	cell migration involved in gastrulation
0.61	GO:0003143	embryonic heart tube morphogenesis
0.61	GO:0061371	determination of heart left/right asymmetry
0.61	GO:0030509	BMP signaling pathway
0.61	GO:0097094	craniofacial suture morphogenesis

0.67	GO:0005509	calcium ion binding
0.38	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005634	nucleus
0.42	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q7Z7M1|AGRD2_HUMAN
Adhesion G-protein coupled receptor D2
Search

ADGRD2

0.97	Adhesion G-protein coupled receptor D2

0.71	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0048168	regulation of neuronal synaptic plasticity
0.33	GO:0042752	regulation of circadian rhythm
0.33	GO:0019933	cAMP-mediated signaling
0.33	GO:0016525	negative regulation of angiogenesis
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.32	GO:0015074	DNA integration
0.31	GO:0006508	proteolysis

0.71	GO:0004930	G-protein coupled receptor activity
0.39	GO:0030246	carbohydrate binding
0.34	GO:0046872	metal ion binding
0.32	GO:0004252	serine-type endopeptidase activity
0.32	GO:0005515	protein binding
0.31	GO:0003676	nucleic acid binding

0.35	GO:0005576	extracellular region
0.32	GO:0005886	plasma membrane
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.32

GO:0004252

sp|Q7Z7M8|B3GN8_HUMAN
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
Search

B3GNT8

0.57	Hexosyltransferase

0.74	GO:0006486	protein glycosylation
0.71	GO:0030311	poly-N-acetyllactosamine biosynthetic process
0.33	GO:0006508	proteolysis

0.81	GO:0008378	galactosyltransferase activity
0.71	GO:0016262	protein N-acetylglucosaminyltransferase activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.74	GO:0000139	Golgi membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008378

sp|Q7Z7M9|GALT5_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 5
Search

GALNT5

0.52	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0006486	protein glycosylation
0.35	GO:0006024	glycosaminoglycan biosynthetic process
0.34	GO:0044206	UMP salvage
0.34	GO:0009166	nucleotide catabolic process
0.33	GO:0009226	nucleotide-sugar biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.68	GO:0030246	carbohydrate binding
0.64	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0004850	uridine phosphorylase activity
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0004497	monooxygenase activity
0.32	GO:0048037	cofactor binding
0.32	GO:0046906	tetrapyrrole binding

0.71	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:2.4.1.41

GO:0004653

sp|Q7Z7N9|T179B_HUMAN
Transmembrane protein 179B
Search

TMEM179B

0.97	Transmembrane protein 179B

0.45	GO:0051090	regulation of DNA binding transcription factor activity
0.41	GO:0006352	DNA-templated transcription, initiation
0.40	GO:0043312	neutrophil degranulation

0.42	GO:0046982	protein heterodimerization activity
0.36	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0003676	nucleic acid binding

0.68	GO:0016607	nuclear speck
0.62	GO:0005730	nucleolus
0.46	GO:0046695	SLIK (SAGA-like) complex
0.45	GO:0000124	SAGA complex
0.45	GO:0005669	transcription factor TFIID complex
0.40	GO:0101003	ficolin-1-rich granule membrane
0.40	GO:0035577	azurophil granule membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.7.7.6

GO:0003899

sp|Q86SE5|RALYL_HUMAN
RNA-binding Raly-like protein
Search

RALYL

0.97	RALY RNA binding protein like

0.58	GO:0003723	RNA binding
0.51	GO:0042802	identical protein binding

0.43	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q86SE8|NPM2_HUMAN
Nucleoplasmin-2
Search

NPM2

0.83	Nucleophosmin/nucleoplasmin 2

0.81	GO:0045836	positive regulation of meiotic nuclear division
0.79	GO:0001824	blastocyst development
0.78	GO:0009994	oocyte differentiation
0.77	GO:0007096	regulation of exit from mitosis
0.76	GO:0007338	single fertilization
0.71	GO:0006338	chromatin remodeling
0.50	GO:0008543	fibroblast growth factor receptor signaling pathway
0.49	GO:0045740	positive regulation of DNA replication
0.48	GO:0065009	regulation of molecular function
0.47	GO:0051260	protein homooligomerization

0.69	GO:0003682	chromatin binding
0.50	GO:0005104	fibroblast growth factor receptor binding
0.48	GO:0008083	growth factor activity
0.45	GO:0019899	enzyme binding
0.42	GO:0042393	histone binding
0.36	GO:0004222	metalloendopeptidase activity
0.36	GO:0003723	RNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003677	DNA binding
0.33	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity

0.85	GO:0000789	cytoplasmic chromatin
0.69	GO:0000790	nuclear chromatin
0.43	GO:0005576	extracellular region
0.35	GO:0005730	nucleolus
0.34	GO:0005680	anaphase-promoting complex
0.34	GO:0005654	nucleoplasm
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005856	cytoskeleton
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004222

sp|Q86SE9|PCGF5_HUMAN
Polycomb group RING finger protein 5
Search

PCGF5

0.97	Polycomb group RING finger protein 5

0.72	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:0060819	inactivation of X chromosome by genetic imprinting
0.51	GO:0036353	histone H2A-K119 monoubiquitination
0.39	GO:0006351	transcription, DNA-templated

0.40	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding
0.38	GO:0016874	ligase activity

0.81	GO:0031519	PcG protein complex
0.74	GO:0005813	centrosome
0.70	GO:0005730	nucleolus
0.51	GO:0000805	X chromosome
0.41	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.38	EC:6	GO:0016874
0.40	KEGG:R03876	GO:0004842

sp|Q86SF2|GALT7_HUMAN
N-acetylgalactosaminyltransferase 7
Search

GALNT7

0.64	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0006486	protein glycosylation
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.68	GO:0030246	carbohydrate binding
0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.43	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0046872	metal ion binding
0.33	GO:0003735	structural constituent of ribosome

0.71	GO:0000139	Golgi membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.63

GO:0016757

sp|Q86SG2|ANR23_HUMAN
Ankyrin repeat domain-containing protein 23
Search

ANKRD23

0.96	Ankyrin repeat domain-containing protein 1

0.54	GO:0035914	skeletal muscle cell differentiation
0.52	GO:1901796	regulation of signal transduction by p53 class mediator
0.51	GO:2000291	regulation of myoblast proliferation
0.50	GO:0010832	negative regulation of myotube differentiation
0.50	GO:0045662	negative regulation of myoblast differentiation
0.50	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress
0.48	GO:0042981	regulation of apoptotic process
0.47	GO:0045445	myoblast differentiation
0.47	GO:0001817	regulation of cytokine production
0.46	GO:1903507	negative regulation of nucleic acid-templated transcription

0.84	GO:0031432	titin binding
0.55	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding
0.51	GO:0043422	protein kinase B binding
0.46	GO:0003712	transcription cofactor activity
0.46	GO:0003682	chromatin binding
0.43	GO:0070412	R-SMAD binding
0.42	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.42	GO:0002039	p53 binding
0.42	GO:0042826	histone deacetylase binding
0.36	GO:0003677	DNA binding

0.55	GO:0005829	cytosol
0.55	GO:0031981	nuclear lumen
0.55	GO:0031674	I band
0.53	GO:0015629	actin cytoskeleton
0.48	GO:0000791	euchromatin
0.39	GO:0005667	transcription factor complex
0.39	GO:0014704	intercalated disc
0.34	GO:1905369	endopeptidase complex
0.30	GO:0016020	membrane

0.33

EC:4

GO:0016829

sp|Q86SG3|DAZ4_HUMAN
Deleted in azoospermia protein 4
Search

0.86	Deleted in azoospermia protein 4

0.80	GO:0007281	germ cell development
0.56	GO:0045727	positive regulation of translation
0.30	GO:0006446	regulation of translational initiation
0.30	GO:0048232	male gamete generation
0.30	GO:0007275	multicellular organism development
0.30	GO:0061013	regulation of mRNA catabolic process
0.30	GO:0045934	negative regulation of nucleobase-containing compound metabolic process
0.30	GO:0031330	negative regulation of cellular catabolic process
0.30	GO:0065008	regulation of biological quality
0.30	GO:0010605	negative regulation of macromolecule metabolic process

0.76	GO:0003729	mRNA binding
0.62	GO:0008494	translation activator activity
0.30	GO:0005515	protein binding

0.30	GO:0044464	cell part
0.30	GO:0032991	macromolecular complex
0.30	GO:0043226	organelle

sp|Q86SG4|DPCA2_HUMAN
Putative Dresden prostate carcinoma protein 2
Search

0.30	Putative Dresden prostate carcinoma protein 2

sp|Q86SG5|S1A7A_HUMAN
Protein S100-A7A
Search

0.47	GO:0010820	positive regulation of T cell chemotaxis
0.46	GO:0090026	positive regulation of monocyte chemotaxis
0.46	GO:0071624	positive regulation of granulocyte chemotaxis
0.46	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.46	GO:0051238	sequestering of metal ion
0.45	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.44	GO:0050829	defense response to Gram-negative bacterium
0.44	GO:0032496	response to lipopolysaccharide
0.42	GO:0000302	response to reactive oxygen species
0.39	GO:0043312	neutrophil degranulation

0.70	GO:0005509	calcium ion binding
0.57	GO:0046914	transition metal ion binding
0.46	GO:0050786	RAGE receptor binding
0.43	GO:0043621	protein self-association
0.33	GO:0005198	structural molecule activity

0.46	GO:0005615	extracellular space
0.42	GO:0031012	extracellular matrix
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005829	cytosol
0.40	GO:0035578	azurophil granule lumen
0.39	GO:0005634	nucleus
0.38	GO:0005925	focal adhesion
0.38	GO:1903561	extracellular vesicle

sp|Q86SG6|NEK8_HUMAN
Serine/threonine-protein kinase Nek8
Search

NEK8

0.95	NIMA (Never in mitosis gene a)-related kinase 8

0.68	GO:0035330	regulation of hippo signaling
0.64	GO:0007368	determination of left/right symmetry
0.63	GO:0006468	protein phosphorylation
0.62	GO:0007507	heart development
0.61	GO:0009887	animal organ morphogenesis

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0097543	ciliary inversin compartment
0.67	GO:0097546	ciliary base
0.30	GO:0031224	intrinsic component of membrane

sp|Q86SG7|LYG2_HUMAN
Lysozyme g-like protein 2
Search

0.86	Goose-type lysozyme 1

0.76	GO:0016998	cell wall macromolecule catabolic process
0.73	GO:0009253	peptidoglycan catabolic process
0.59	GO:0050830	defense response to Gram-positive bacterium
0.37	GO:0019835	cytolysis

0.77

GO:0003796

lysozyme activity

0.50	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.77

EC:3.2.1.17

GO:0003796

sp|Q86SH2|ZAR1_HUMAN
Zygote arrest protein 1
Search

ZAR1

0.82	Zygote arrest protein 1

0.55	GO:0007275	multicellular organism development
0.42	GO:1905881	positive regulation of oogenesis
0.41	GO:0016441	posttranscriptional gene silencing
0.40	GO:0000003	reproduction
0.40	GO:0017148	negative regulation of translation

0.43	GO:1903231	mRNA binding involved in posttranscriptional gene silencing
0.37	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q86SH4|PRNT_HUMAN
Putative testis-specific prion protein
Search

PRNT

0.97	Prion protein, testis-specific protein Prt

0.66

GO:0005576

extracellular region

sp|Q86SI9|CEI_HUMAN
Protein CEI
Search

sp|Q86SJ2|AMGO2_HUMAN
Amphoterin-induced protein 2
Search

AMIGO2

0.97	Adhesion molecule with Ig like domain 2

0.73	GO:0043066	negative regulation of apoptotic process
0.64	GO:0051965	positive regulation of synapse assembly
0.56	GO:0007413	axonal fasciculation
0.55	GO:0042552	myelination
0.51	GO:0007155	cell adhesion
0.44	GO:1901381	positive regulation of potassium ion transmembrane transport
0.39	GO:0065009	regulation of molecular function
0.39	GO:0007420	brain development
0.35	GO:0050772	positive regulation of axonogenesis
0.35	GO:0007409	axonogenesis

0.45	GO:0015459	potassium channel regulator activity
0.36	GO:0005515	protein binding

0.47	GO:0005887	integral component of plasma membrane
0.45	GO:0032809	neuronal cell body membrane
0.43	GO:0030425	dendrite
0.42	GO:0034705	potassium channel complex
0.36	GO:0005634	nucleus
0.35	GO:0043204	perikaryon
0.34	GO:0030424	axon

sp|Q86SJ6|DSG4_HUMAN
Desmoglein-4
Search

DSG3

0.97	LOW QUALITY PROTEIN: desmoglein-4

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.62	GO:0001942	hair follicle development
0.62	GO:0030216	keratinocyte differentiation
0.61	GO:0030509	BMP signaling pathway
0.40	GO:0050821	protein stabilization
0.38	GO:0012501	programmed cell death

0.70	GO:0005509	calcium ion binding
0.42	GO:0045295	gamma-catenin binding

0.63	GO:0030057	desmosome
0.55	GO:0005886	plasma membrane
0.39	GO:0098562	cytoplasmic side of membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:0005914	spot adherens junction
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q86SK9|SCD5_HUMAN
Stearoyl-CoA desaturase 5
Search

SCD5

0.58	Stearoyl-CoA desaturase

0.70	GO:0006633	fatty acid biosynthetic process
0.56	GO:0033559	unsaturated fatty acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0046949	fatty-acyl-CoA biosynthetic process
0.34	GO:0001510	RNA methylation
0.34	GO:0006396	RNA processing

0.80	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
0.35	GO:0005506	iron ion binding
0.34	GO:0008173	RNA methyltransferase activity

0.49	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

0.80

EC:1.14.19

GO:0016717

sp|Q86SM5|MRGRG_HUMAN
Mas-related G-protein coupled receptor member G
Search

MRGPRG

0.92	MAS related GPR family member G

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:1902349	response to chloroquine
0.37	GO:0007166	cell surface receptor signaling pathway

0.72

GO:0004930

G-protein coupled receptor activity

0.41

GO:0005887

integral component of plasma membrane

sp|Q86SM8|MRGRE_HUMAN
Mas-related G-protein coupled receptor member E
Search

0.95	Mas-related G-protein coupled receptor member E

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:1903955	positive regulation of protein targeting to mitochondrion
0.37	GO:0002279	mast cell activation involved in immune response
0.37	GO:0002448	mast cell mediated immunity
0.37	GO:0043299	leukocyte degranulation
0.37	GO:0032418	lysosome localization
0.36	GO:0051656	establishment of organelle localization
0.35	GO:0032467	positive regulation of cytokinesis
0.35	GO:0046907	intracellular transport

0.72	GO:0004930	G-protein coupled receptor activity
0.35	GO:0042923	neuropeptide binding

0.43	GO:0005887	integral component of plasma membrane
0.37	GO:0042629	mast cell granule

sp|Q86SP6|GP149_HUMAN
Probable G-protein coupled receptor 149
Search

GPR149

0.90	G protein-coupled receptor 149

0.69	GO:0060280	negative regulation of ovulation
0.67	GO:0001547	antral ovarian follicle growth
0.66	GO:0048162	multi-layer follicle stage
0.51	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0007268	chemical synaptic transmission

0.52	GO:0042923	neuropeptide binding
0.52	GO:0004930	G-protein coupled receptor activity

0.48	GO:0043005	neuron projection
0.44	GO:0005887	integral component of plasma membrane

sp|Q86SQ0|PHLB2_HUMAN
Pleckstrin homology-like domain family B member 2
Search

PHLDB2

0.96	Pleckstrin homology like domain family B member 2

0.87	GO:1903690	negative regulation of wound healing, spreading of epidermal cells
0.87	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis
0.86	GO:1901203	positive regulation of extracellular matrix assembly
0.86	GO:0051497	negative regulation of stress fiber assembly
0.86	GO:0051895	negative regulation of focal adhesion assembly
0.85	GO:0040019	positive regulation of embryonic development
0.85	GO:0010470	regulation of gastrulation
0.84	GO:0010717	regulation of epithelial to mesenchymal transition
0.80	GO:0070507	regulation of microtubule cytoskeleton organization
0.75	GO:0000226	microtubule cytoskeleton organization

0.81

GO:0045296

cadherin binding

0.86	GO:0045180	basal cortex
0.81	GO:0005925	focal adhesion
0.80	GO:0031252	cell leading edge
0.77	GO:0045111	intermediate filament cytoskeleton
0.67	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q86SQ3|AGRE4_HUMAN
Putative adhesion G protein-coupled receptor E4P
Search

0.84	LOW QUALITY PROTEIN: EGF-like module-containing mucin-like hormone receptor-like 3

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0007166	cell surface receptor signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.60	GO:0005509	calcium ion binding

0.30

GO:0044425

membrane part

sp|Q86SQ4|AGRG6_HUMAN
Adhesion G-protein coupled receptor G6
Search

ADGRG6

0.94	Adhesion G-protein coupled receptor G6

0.73	GO:0060347	heart trabecula formation
0.72	GO:0014037	Schwann cell differentiation
0.71	GO:0032292	peripheral nervous system axon ensheathment
0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0042552	myelination
0.70	GO:0019933	cAMP-mediated signaling
0.69	GO:0021782	glial cell development
0.63	GO:0007005	mitochondrion organization
0.37	GO:0060879	semicircular canal fusion

0.72	GO:0004930	G-protein coupled receptor activity
0.71	GO:0043236	laminin binding
0.42	GO:0005518	collagen binding

0.49	GO:0005886	plasma membrane
0.41	GO:0005622	intracellular
0.36	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q86SQ6|AGRA1_HUMAN
Adhesion G protein-coupled receptor A1
Search

ADGRA1

0.97	Adhesion G protein-coupled receptor A1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0097475	motor neuron migration
0.36	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway
0.35	GO:0060027	convergent extension involved in gastrulation
0.35	GO:0003401	axis elongation
0.35	GO:0198738	cell-cell signaling by wnt

0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.49	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q86SQ7|SDCG8_HUMAN
Serologically defined colon cancer antigen 8
Search

SDCCAG8

0.97	Serologically defined colon cancer antigen 8

0.82	GO:0007098	centrosome cycle
0.60	GO:0001764	neuron migration
0.60	GO:0035148	tube formation
0.59	GO:0030010	establishment of cell polarity
0.41	GO:0043009	chordate embryonic development
0.38	GO:0097711	ciliary basal body-plasma membrane docking
0.37	GO:0000086	G2/M transition of mitotic cell cycle
0.36	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.35

GO:0005515

protein binding

0.77	GO:0005813	centrosome
0.61	GO:0005814	centriole
0.57	GO:0005911	cell-cell junction
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q86SQ9|DHDDS_HUMAN
Dehydrodolichyl diphosphate synthase complex subunit DHDDS
Search

DHDDS

0.73	Dehydrodolichyl diphosphate synthase complex subunit DHDDS

0.73	GO:0043413	macromolecule glycosylation
0.73	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0006464	cellular protein modification process
0.49	GO:0016094	polyprenol biosynthetic process
0.46	GO:0050908	detection of light stimulus involved in visual perception
0.45	GO:0042462	eye photoreceptor cell development
0.36	GO:0006489	dolichyl diphosphate biosynthetic process

0.69	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.35	GO:0031492	nucleosomal DNA binding
0.33	GO:0005515	protein binding

0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0000785	chromatin
0.33	GO:0005634	nucleus

0.69

EC:2.5 EC:2.5.1

GO:0016765

sp|Q86SR1|GLT10_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 10
Search

GALNT10

0.65	Polypeptide N-acetylgalactosaminyltransferase

0.73	GO:0043413	macromolecule glycosylation
0.73	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process

0.69	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.45	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0046872	metal ion binding

0.73	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

sp|Q86SS6|SYT9_HUMAN
Synaptotagmin-9
Search

SYT9

0.97	Synaptotagmin IXb

0.85	GO:0017158	regulation of calcium ion-dependent exocytosis
0.84	GO:0050796	regulation of insulin secretion
0.50	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.48	GO:0006906	vesicle fusion
0.39	GO:1903307	positive regulation of regulated secretory pathway
0.36	GO:0005513	detection of calcium ion

0.56	GO:0001786	phosphatidylserine binding
0.55	GO:0000149	SNARE binding
0.55	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.49	GO:0042802	identical protein binding
0.48	GO:0005544	calcium-dependent phospholipid binding
0.47	GO:0030276	clathrin binding
0.44	GO:0005509	calcium ion binding

0.57	GO:0031045	dense core granule
0.47	GO:0098793	presynapse
0.39	GO:0005886	plasma membrane
0.39	GO:0099501	exocytic vesicle membrane
0.39	GO:0030667	secretory granule membrane
0.37	GO:0030054	cell junction
0.35	GO:0030665	clathrin-coated vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|Q86SU0|ILDR1_HUMAN
Immunoglobulin-like domain-containing receptor 1
Search

ILDR1

0.97	Immunoglobulin like domain containing receptor 1

0.62	GO:0090277	positive regulation of peptide hormone secretion
0.61	GO:1990830	cellular response to leukemia inhibitory factor
0.59	GO:0051260	protein homooligomerization
0.54	GO:0006898	receptor-mediated endocytosis
0.44	GO:0048922	posterior lateral line neuromast deposition
0.44	GO:1904274	tricellular tight junction assembly
0.44	GO:0061833	protein localization to tricellular tight junction
0.43	GO:0060872	semicircular canal development
0.43	GO:0060856	establishment of blood-brain barrier
0.42	GO:0001889	liver development

0.67	GO:0070506	high-density lipoprotein particle receptor activity
0.56	GO:0042802	identical protein binding
0.33	GO:0017129	triglyceride binding
0.33	GO:0030169	low-density lipoprotein particle binding
0.33	GO:0005504	fatty acid binding
0.32	GO:0046983	protein dimerization activity

0.66	GO:0061689	tricellular tight junction
0.48	GO:0043234	protein complex
0.46	GO:0005886	plasma membrane
0.38	GO:0005829	cytosol
0.35	GO:0034362	low-density lipoprotein particle
0.35	GO:0042627	chylomicron
0.35	GO:0034361	very-low-density lipoprotein particle
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q86SX3|CN080_HUMAN
Uncharacterized protein C14orf80
Search

sp|Q86SX6|GLRX5_HUMAN
Glutaredoxin-related protein 5, mitochondrial
Search

GLRX5

0.76	Glutaredoxin-related protein 5, mitochondrial

0.69	GO:0045454	cell redox homeostasis
0.61	GO:0022900	electron transport chain
0.47	GO:0030097	hemopoiesis
0.44	GO:0009249	protein lipoylation
0.37	GO:0016226	iron-sulfur cluster assembly
0.35	GO:0044281	small molecule metabolic process

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.66	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.51	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding

0.45	GO:0043025	neuronal cell body
0.45	GO:0030425	dendrite
0.43	GO:0005759	mitochondrial matrix
0.39	GO:0005634	nucleus

sp|Q86SY8|KTAS1_HUMAN
Putative uncharacterized protein KTN1-AS1
Search

sp|Q86SZ2|TPC6B_HUMAN
Trafficking protein particle complex subunit 6B
Search

TRAPPC6B

0.89	Trafficking protein particle complex subunit 6B

0.76	GO:0048193	Golgi vesicle transport
0.75	GO:0043087	regulation of GTPase activity
0.45	GO:0046907	intracellular transport
0.36	GO:0006900	vesicle budding from membrane
0.35	GO:0006903	vesicle targeting
0.34	GO:0006461	protein complex assembly
0.33	GO:0034613	cellular protein localization
0.33	GO:0015031	protein transport

0.35

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.49	GO:0005801	cis-Golgi network
0.49	GO:0030008	TRAPP complex
0.48	GO:0005802	trans-Golgi network
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0000139	Golgi membrane
0.34	GO:0030127	COPII vesicle coat
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q86T03|TM55B_HUMAN
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
Search

TMEM55B

0.97	Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A

0.81

GO:0046856

phosphatidylinositol dephosphorylation

0.86

GO:0034597

phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity

0.56	GO:0031902	late endosome membrane
0.55	GO:0005765	lysosomal membrane
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:3.1.3.66

GO:0034597

sp|Q86T13|CLC14_HUMAN
C-type lectin domain family 14 member A
Search

CLEC14A

0.97	C-type lectin domain containing 14A

0.39

GO:0002042

cell migration involved in sprouting angiogenesis

0.76	GO:1990430	extracellular matrix protein binding
0.57	GO:0030246	carbohydrate binding

0.68	GO:0009897	external side of plasma membrane
0.43	GO:0070062	extracellular exosome
0.43	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|Q86T20|CF001_HUMAN
Uncharacterized protein C6orf1
Search

SMIM29

0.96	Small integral membrane protein 29

0.66

GO:0005576

extracellular region

sp|Q86T23|CROL1_HUMAN
Putative ciliary rootlet coiled-coil protein-like 1 protein
Search

0.12	Putative ciliary rootlet coiled-coil protein-like 1 protein

0.83	GO:0007098	centrosome cycle
0.72	GO:1903566	positive regulation of protein localization to cilium
0.71	GO:0032053	ciliary basal body organization
0.69	GO:0045724	positive regulation of cilium assembly
0.68	GO:0010669	epithelial structure maintenance
0.67	GO:0045494	photoreceptor cell maintenance
0.61	GO:0051656	establishment of organelle localization
0.58	GO:0033365	protein localization to organelle

0.67	GO:0019894	kinesin binding
0.59	GO:0003779	actin binding
0.51	GO:0005198	structural molecule activity

0.86	GO:0035253	ciliary rootlet
0.67	GO:0001917	photoreceptor inner segment
0.65	GO:0005814	centriole
0.63	GO:0005813	centrosome
0.60	GO:0015629	actin cytoskeleton
0.56	GO:0005829	cytosol
0.47	GO:0005886	plasma membrane
0.44	GO:0070062	extracellular exosome

sp|Q86T24|KAISO_HUMAN
Transcriptional regulator Kaiso
Search

ZBTB33

0.97	Transcriptional regulator Kaiso

0.55	GO:0045892	negative regulation of transcription, DNA-templated
0.38	GO:0016055	Wnt signaling pathway
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0042074	cell migration involved in gastrulation
0.34	GO:0030178	negative regulation of Wnt signaling pathway
0.34	GO:0035556	intracellular signal transduction
0.32	GO:0060027	convergent extension involved in gastrulation
0.32	GO:0009953	dorsal/ventral pattern formation

0.66	GO:0008327	methyl-CpG binding
0.41	GO:0010428	methyl-CpNpG binding
0.39	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0019901	protein kinase binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:1990837	sequence-specific double-stranded DNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0008013	beta-catenin binding

0.55	GO:0005730	nucleolus
0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane
0.33	GO:0005694	chromosome

sp|Q86T26|TM11B_HUMAN
Transmembrane protease serine 11B
Search

0.91	Transmembrane protease serine

0.59	GO:0006508	proteolysis
0.34	GO:0007596	blood coagulation
0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0043010	camera-type eye development
0.33	GO:0007049	cell cycle

0.67	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0005509	calcium ion binding

0.58	GO:0005887	integral component of plasma membrane
0.58	GO:0005576	extracellular region
0.44	GO:0043204	perikaryon
0.42	GO:0030425	dendrite
0.37	GO:0031982	vesicle
0.33	GO:0005789	endoplasmic reticulum membrane

0.67

GO:0004252

sp|Q86T29|ZN605_HUMAN
Zinc finger protein 605
Search

0.68	RB associated KRAB zinc finger

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0097659	nucleic acid-templated transcription
0.45	GO:0010467	gene expression
0.45	GO:0034645	cellular macromolecule biosynthetic process

0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.50	GO:0003700	DNA binding transcription factor activity

0.55	GO:0005634	nucleus
0.46	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part

sp|Q86T65|DAAM2_HUMAN
Disheveled-associated activator of morphogenesis 2
Search

DAAM2

0.94	Dishevelled associated activator of morphogenesis 2

0.73	GO:0030036	actin cytoskeleton organization
0.53	GO:0048715	negative regulation of oligodendrocyte differentiation
0.52	GO:0021516	dorsal spinal cord development
0.52	GO:2000050	regulation of non-canonical Wnt signaling pathway
0.51	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.50	GO:0007368	determination of left/right symmetry
0.36	GO:0030838	positive regulation of actin filament polymerization
0.36	GO:0097435	supramolecular fiber organization
0.35	GO:0060071	Wnt signaling pathway, planar cell polarity pathway

0.77	GO:0017048	Rho GTPase binding
0.73	GO:0003779	actin binding
0.46	GO:0042802	identical protein binding
0.36	GO:0008017	microtubule binding
0.32	GO:0003676	nucleic acid binding

0.50	GO:0097517	contractile actin filament bundle
0.50	GO:0042641	actomyosin
0.49	GO:0036064	ciliary basal body
0.48	GO:0031514	motile cilium
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.37	GO:0005884	actin filament
0.36	GO:0070062	extracellular exosome

sp|Q86T75|NBPFB_HUMAN
Neuroblastoma breakpoint family member 11
Search

0.10	Neuroblastoma breakpoint family member 11

0.48	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q86T82|UBP37_HUMAN
Ubiquitin carboxyl-terminal hydrolase 37
Search

USP37

0.96	Ubiquitin carboxyl-terminal hydrolase 37

0.75	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.58	GO:0000082	G1/S transition of mitotic cell cycle
0.53	GO:0006275	regulation of DNA replication
0.39	GO:0051301	cell division
0.33	GO:0021551	central nervous system morphogenesis
0.33	GO:1904888	cranial skeletal system development

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.53	GO:0019901	protein kinase binding
0.53	GO:0004197	cysteine-type endopeptidase activity

0.45	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.76

EC:3.4.19.12

GO:0036459

sp|Q86T90|K1328_HUMAN
Protein hinderin
Search

0.37

GO:0016310

phosphorylation

0.54	GO:0005515	protein binding
0.38	GO:0016301	kinase activity

0.30

GO:0044425

membrane part

sp|Q86T96|RN180_HUMAN
E3 ubiquitin-protein ligase RNF180
Search

RNF180

0.52	E3 ubiquitin-protein ligase

0.82	GO:0000209	protein polyubiquitination
0.52	GO:0042415	norepinephrine metabolic process
0.52	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.51	GO:0042428	serotonin metabolic process
0.49	GO:0030534	adult behavior
0.40	GO:0031398	positive regulation of protein ubiquitination
0.37	GO:0050790	regulation of catalytic activity
0.32	GO:0006783	heme biosynthetic process
0.32	GO:0043043	peptide biosynthetic process
0.31	GO:0010467	gene expression

0.76	GO:0061630	ubiquitin protein ligase activity
0.52	GO:0031624	ubiquitin conjugating enzyme binding
0.50	GO:0016874	ligase activity
0.36	GO:0046872	metal ion binding
0.32	GO:0004325	ferrochelatase activity
0.32	GO:0003735	structural constituent of ribosome

0.41	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005635	nuclear envelope
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.50	EC:6	GO:0016874
0.32	KEGG:R00310	GO:0004325

sp|Q86TA1|MOB3B_HUMAN
MOB kinase activator 3B
Search

MOB3B

0.94	MOB kinase activator 3B

0.55	GO:0016310	phosphorylation
0.34	GO:0006464	cellular protein modification process

0.57	GO:0016301	kinase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0005515	protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.1

GO:0016773

sp|Q86TA4|YB049_HUMAN
Putative uncharacterized protein FLJ44553
Search

sp|Q86TB3|ALPK2_HUMAN
Alpha-protein kinase 2
Search

ALPK2

0.88	Alpha-protein kinase 2

0.62	GO:0006468	protein phosphorylation
0.37	GO:0007507	heart development
0.36	GO:0055002	striated muscle cell development
0.36	GO:0014706	striated muscle tissue development
0.35	GO:1901642	nucleoside transmembrane transport

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005337	nucleoside transmembrane transporter activity

0.37	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.69

GO:0004674

sp|Q86TB9|PATL1_HUMAN
Protein PAT1 homolog 1
Search

PATL1

0.97	PAT1 homolog 1, processing body mRNA decay factor

0.83	GO:0033962	cytoplasmic mRNA processing body assembly
0.79	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.44	GO:0006869	lipid transport
0.40	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.39	GO:0017148	negative regulation of translation
0.37	GO:0010607	negative regulation of cytoplasmic mRNA processing body assembly
0.36	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.31	GO:0006468	protein phosphorylation

0.82	GO:0034046	poly(G) binding
0.78	GO:0008266	poly(U) RNA binding
0.41	GO:0002151	G-quadruplex RNA binding
0.41	GO:0030371	translation repressor activity
0.40	GO:0016853	isomerase activity
0.36	GO:0004984	olfactory receptor activity
0.36	GO:0005515	protein binding
0.36	GO:0004930	G-protein coupled receptor activity
0.31	GO:0004672	protein kinase activity
0.31	GO:0030554	adenyl nucleotide binding

0.77	GO:0000932	P-body
0.75	GO:0030014	CCR4-NOT complex
0.49	GO:0016605	PML body
0.48	GO:0016607	nuclear speck
0.37	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:5

GO:0016853

sp|Q86TC9|MYPN_HUMAN
Myopalladin
Search

MYPN

0.90	Myopalladin

0.79	GO:0055002	striated muscle cell development
0.75	GO:0031032	actomyosin structure organization
0.75	GO:0010927	cellular component assembly involved in morphogenesis
0.68	GO:0097435	supramolecular fiber organization
0.66	GO:0070925	organelle assembly
0.63	GO:0055006	cardiac cell development
0.63	GO:0055007	cardiac muscle cell differentiation
0.59	GO:0030334	regulation of cell migration
0.57	GO:0051493	regulation of cytoskeleton organization
0.47	GO:0016477	cell migration

0.83	GO:0051371	muscle alpha-actinin binding
0.73	GO:0017124	SH3 domain binding
0.58	GO:0051015	actin filament binding
0.33	GO:0004984	olfactory receptor activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0004930	G-protein coupled receptor activity

0.80	GO:0030018	Z disc
0.39	GO:0005634	nucleus
0.38	GO:0005884	actin filament
0.36	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q86TD4|SRCA_HUMAN
Sarcalumenin
Search

SRL

0.79	Sarcalumenin

0.54	GO:0014873	response to muscle activity involved in regulation of muscle adaptation
0.52	GO:0002115	store-operated calcium entry

0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0033018	sarcoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|Q86TE4|LUZP2_HUMAN
Leucine zipper protein 2
Search

LUZP2

0.97	Leucine zipper protein 2

0.36

GO:0006606

protein import into nucleus

0.60	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q86TG1|T150A_HUMAN
Transmembrane protein 150A
Search

TMEM150A

0.90	DNA damage-regulated autophagy modulator protein 2

0.57	GO:0072659	protein localization to plasma membrane
0.53	GO:0046854	phosphatidylinositol phosphorylation
0.35	GO:0009056	catabolic process

0.33

GO:0005515

protein binding

0.49	GO:0005887	integral component of plasma membrane
0.48	GO:0005764	lysosome

sp|Q86TG7|PEG10_HUMAN
Retrotransposon-derived protein PEG10
Search

PEG10

0.65	LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10

0.53	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.50	GO:0006915	apoptotic process
0.47	GO:0030154	cell differentiation
0.43	GO:0001890	placenta development

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0005515	protein binding

0.59	GO:0005829	cytosol
0.54	GO:0005634	nucleus

sp|Q86TH1|ATL2_HUMAN
ADAMTS-like protein 2
Search

ADAMTSL2

0.97	ADAMTS like 2

0.64	GO:0060481	lobar bronchus epithelium development
0.60	GO:0006508	proteolysis
0.60	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.57	GO:0030198	extracellular matrix organization

0.65	GO:0050436	microfibril binding
0.60	GO:0008233	peptidase activity
0.34	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.54	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016021	integral component of membrane

0.60

GO:0008233

sp|Q86TI0|TBCD1_HUMAN
TBC1 domain family member 1
Search

TBC1D1

0.87	TBC1 domain family member 1 isoform 1

0.80	GO:0031338	regulation of vesicle fusion
0.79	GO:0090630	activation of GTPase activity
0.65	GO:0006886	intracellular protein transport
0.58	GO:0032880	regulation of protein localization
0.55	GO:1902017	regulation of cilium assembly
0.47	GO:0061024	membrane organization

0.76	GO:0017137	Rab GTPase binding
0.72	GO:0005096	GTPase activator activity

0.64	GO:0012505	endomembrane system
0.49	GO:0005634	nucleus
0.47	GO:0005829	cytosol

sp|Q86TI2|DPP9_HUMAN
Dipeptidyl peptidase 9
Search

DPP9

0.96	Dipeptidyl peptidase 9

0.61

GO:0006508

proteolysis

0.66	GO:0008236	serine-type peptidase activity
0.49	GO:0042802	identical protein binding
0.35	GO:0004177	aminopeptidase activity
0.32	GO:0008234	cysteine-type peptidase activity

0.47	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.35

EC:3.4.11

GO:0004177

sp|Q86TI4|WDR86_HUMAN
WD repeat-containing protein 86
Search

WDR86

0.97	WD repeat-containing protein 86

sp|Q86TJ2|TAD2B_HUMAN
Transcriptional adapter 2-beta
Search

TADA2B

0.79	Transcriptional adapter

0.74	GO:0035065	regulation of histone acetylation
0.63	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0006351	transcription, DNA-templated
0.50	GO:2000758	positive regulation of peptidyl-lysine acetylation
0.49	GO:0031058	positive regulation of histone modification
0.47	GO:0016573	histone acetylation
0.47	GO:0006338	chromatin remodeling
0.35	GO:0016579	protein deubiquitination

0.70	GO:0003713	transcription coactivator activity
0.55	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.47	GO:0004402	histone acetyltransferase activity
0.46	GO:0003682	chromatin binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0005515	protein binding

0.57	GO:0005634	nucleus
0.54	GO:0031248	protein acetyltransferase complex
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0043234	protein complex
0.44	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:2.3.1.48

GO:0004402

sp|Q86TJ5|ZN554_HUMAN
Zinc finger protein 554
Search

ZNF554

0.82	Zinc finger protein 554

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.41	GO:0006351	transcription, DNA-templated
0.36	GO:0042035	regulation of cytokine biosynthetic process
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003682	chromatin binding

0.56	GO:0005730	nucleolus
0.35	GO:0097197	tetraspanin-enriched microdomain
0.35	GO:0001772	immunological synapse
0.30	GO:0031224	intrinsic component of membrane

sp|Q86TL0|ATG4D_HUMAN
Cysteine protease ATG4D
Search

ATG4D

0.59	Cysteine protease

0.77	GO:0006914	autophagy
0.65	GO:0015031	protein transport
0.60	GO:0006508	proteolysis
0.53	GO:0051697	protein delipidation
0.52	GO:0006501	C-terminal protein lipidation
0.51	GO:0007033	vacuole organization
0.50	GO:0061726	mitochondrion disassembly
0.47	GO:0070925	organelle assembly
0.46	GO:0090150	establishment of protein localization to membrane
0.44	GO:0046907	intracellular transport

0.72	GO:0008234	cysteine-type peptidase activity
0.47	GO:0004175	endopeptidase activity

0.48	GO:0005737	cytoplasm
0.38	GO:0005576	extracellular region
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.35	GO:0043231	intracellular membrane-bounded organelle

0.72

GO:0008234

sp|Q86TL2|STIMA_HUMAN
Store-operated calcium entry regulator STIMATE
Search

TMEM110

0.90	Transmembrane protein 110

0.44	GO:0035988	chondrocyte proliferation
0.43	GO:0002062	chondrocyte differentiation
0.43	GO:0042246	tissue regeneration

0.38	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q86TM3|DDX53_HUMAN
Probable ATP-dependent RNA helicase DDX53
Search

DDX43

0.97	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43

0.51	GO:0010501	RNA secondary structure unwinding
0.35	GO:0071805	potassium ion transmembrane transport
0.34	GO:0031047	gene silencing by RNA
0.33	GO:0006955	immune response
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006396	RNA processing

0.66	GO:0004386	helicase activity
0.57	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0008186	RNA-dependent ATPase activity
0.43	GO:0140098	catalytic activity, acting on RNA
0.35	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
0.32	GO:0016740	transferase activity

0.47	GO:0005730	nucleolus
0.38	GO:0005737	cytoplasm
0.35	GO:0008076	voltage-gated potassium channel complex

0.33

EC:3.1.30

GO:0016893

sp|Q86TM6|SYVN1_HUMAN
E3 ubiquitin-protein ligase synoviolin
Search

SYVN1

0.91	Synovial apoptosis inhibitor 1, synoviolin

0.81	GO:0030433	ubiquitin-dependent ERAD pathway
0.71	GO:0016567	protein ubiquitination
0.63	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.61	GO:1903513	endoplasmic reticulum to cytosol transport
0.61	GO:0018279	protein N-linked glycosylation via asparagine
0.61	GO:0032527	protein exit from endoplasmic reticulum
0.57	GO:0050821	protein stabilization
0.50	GO:0030968	endoplasmic reticulum unfolded protein response
0.38	GO:0001701	in utero embryonic development
0.37	GO:1904380	endoplasmic reticulum mannose trimming

0.75	GO:0061630	ubiquitin protein ligase activity
0.64	GO:1990381	ubiquitin-specific protease binding
0.61	GO:0051117	ATPase binding
0.56	GO:0051087	chaperone binding
0.54	GO:0051082	unfolded protein binding
0.48	GO:0016874	ligase activity
0.36	GO:0046872	metal ion binding

0.84	GO:0000836	Hrd1p ubiquitin ligase complex
0.64	GO:0036513	Derlin-1 retrotranslocation complex
0.62	GO:0005790	smooth endoplasmic reticulum
0.52	GO:0044322	endoplasmic reticulum quality control compartment
0.52	GO:0005654	nucleoplasm
0.36	GO:0030176	integral component of endoplasmic reticulum membrane

0.48

GO:0016874

sp|Q86TN4|TRPT1_HUMAN
tRNA 2'-phosphotransferase 1
Search

TRPT1

0.95	LOW QUALITY PROTEIN: tRNA 2'-phosphotransferase 1

0.81	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.52	GO:0045859	regulation of protein kinase activity
0.33	GO:0006470	protein dephosphorylation

0.61	GO:0000215	tRNA 2'-phosphotransferase activity
0.33	GO:0004722	protein serine/threonine phosphatase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0046872	metal ion binding

0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.61

EC:2.7.1.160

GO:0000215

sp|Q86TP1|PRUNE_HUMAN
Protein prune homolog
Search

PRUNE1

0.75	Prune exopolyphosphatase

0.63	GO:0031113	regulation of microtubule polymerization
0.59	GO:0050767	regulation of neurogenesis
0.53	GO:0016311	dephosphorylation
0.33	GO:0043412	macromolecule modification
0.33	GO:0044267	cellular protein metabolic process
0.32	GO:0016310	phosphorylation
0.32	GO:0006508	proteolysis
0.31	GO:0016070	RNA metabolic process

0.58	GO:0016462	pyrophosphatase activity
0.56	GO:0015631	tubulin binding
0.53	GO:0016791	phosphatase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0009982	pseudouridine synthase activity
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding

0.53	GO:0005829	cytosol
0.41	GO:0005925	focal adhesion
0.37	GO:0005634	nucleus
0.32	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.58

EC:3.6.1

GO:0016462

sp|Q86TS7|U730_HUMAN
Putative UPF0730 protein encoded by LINC00643
Search

0.77

GO:0006887

exocytosis

sp|Q86TS9|RM52_HUMAN
39S ribosomal protein L52, mitochondrial
Search

MRPL52

0.95	Mitochondrial ribosomal protein L52

0.80	GO:0032543	mitochondrial translation
0.36	GO:0006415	translational termination
0.36	GO:0006414	translational elongation
0.34	GO:0006508	proteolysis

0.63	GO:0003735	structural constituent of ribosome
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding

0.81	GO:0005762	mitochondrial large ribosomal subunit
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.36	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

0.35

GO:0004222

sp|Q86TU6|CN070_HUMAN
Putative uncharacterized protein encoded by LINC00523
Search

sp|Q86TU7|SETD3_HUMAN
Histone-lysine N-methyltransferase setd3
Search

SETD3

0.52	Histone-lysine N-methyltransferase

0.85	GO:0010452	histone H3-K36 methylation
0.85	GO:0018027	peptidyl-lysine dimethylation
0.85	GO:0018026	peptidyl-lysine monomethylation
0.85	GO:0018023	peptidyl-lysine trimethylation
0.57	GO:0051568	histone H3-K4 methylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0051149	positive regulation of muscle cell differentiation
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.53	GO:0010628	positive regulation of gene expression
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.85	GO:0046975	histone methyltransferase activity (H3-K36 specific)
0.79	GO:0003713	transcription coactivator activity
0.58	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.57	GO:0001102	RNA polymerase II activating transcription factor binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0000790	nuclear chromatin
0.34	GO:0005654	nucleoplasm

sp|Q86TV6|TTC7B_HUMAN
Tetratricopeptide repeat protein 7B
Search

TTC7B

0.91	Tetratricopeptide repeat protein 7B

0.79	GO:0072659	protein localization to plasma membrane
0.72	GO:0046854	phosphatidylinositol phosphorylation

0.37

GO:0005515

protein binding

0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q86TW2|ADCK1_HUMAN
Uncharacterized aarF domain-containing protein kinase 1
Search

ADCK1

0.96	AarF domain containing kinase 1

0.59	GO:0006468	protein phosphorylation
0.34	GO:0055088	lipid homeostasis
0.34	GO:0031571	mitotic G1 DNA damage checkpoint
0.33	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.33	GO:0007005	mitochondrion organization

0.59	GO:0004672	protein kinase activity
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0030332	cyclin binding

0.42	GO:0005739	mitochondrion
0.37	GO:0005576	extracellular region
0.33	GO:0019005	SCF ubiquitin ligase complex
0.32	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|Q86TX2|ACOT1_HUMAN
Acyl-coenzyme A thioesterase 1
Search

0.54	Acyl-coenzyme A thioesterase 2, mitochondrial

0.73	GO:0035383	thioester metabolic process
0.65	GO:0032789	unsaturated monocarboxylic acid metabolic process
0.65	GO:0032788	saturated monocarboxylic acid metabolic process
0.63	GO:0006732	coenzyme metabolic process
0.61	GO:0000038	very long-chain fatty acid metabolic process
0.59	GO:0001676	long-chain fatty acid metabolic process
0.54	GO:0006793	phosphorus metabolic process
0.53	GO:0043649	dicarboxylic acid catabolic process
0.53	GO:0046459	short-chain fatty acid metabolic process
0.37	GO:0070849	response to epidermal growth factor

0.76	GO:0016790	thiolester hydrolase activity
0.52	GO:0005102	receptor binding
0.47	GO:0052689	carboxylic ester hydrolase activity

0.55	GO:0005777	peroxisome
0.42	GO:0005829	cytosol
0.40	GO:0005759	mitochondrial matrix
0.40	GO:0070062	extracellular exosome
0.37	GO:0031907	microbody lumen

0.76	EC:3.1.2	GO:0016790
0.47	KEGG:R00630	GO:0052689

sp|Q86TY3|CN037_HUMAN
Uncharacterized protein C14orf37
Search

0.35	GO:0042273	ribosomal large subunit biogenesis
0.34	GO:0051641	cellular localization
0.34	GO:0090304	nucleic acid metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0006996	organelle organization
0.34	GO:0006275	regulation of DNA replication
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0045893	positive regulation of transcription, DNA-templated
0.33	GO:0034654	nucleobase-containing compound biosynthetic process
0.33	GO:0044260	cellular macromolecule metabolic process

0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.34	GO:0003677	DNA binding
0.33	GO:0043021	ribonucleoprotein complex binding
0.32	GO:0061505	DNA topoisomerase II activity
0.32	GO:0046982	protein heterodimerization activity
0.32	GO:0008144	drug binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.32	GO:0008094	DNA-dependent ATPase activity

0.34	GO:0005634	nucleus
0.33	GO:0030687	preribosome, large subunit precursor
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0042025	host cell nucleus
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0030123	AP-3 adaptor complex
0.32	GO:0044446	intracellular organelle part
0.32	GO:0020011	apicoplast
0.32	GO:0000428	DNA-directed RNA polymerase complex
0.32	GO:0005667	transcription factor complex

0.35

EC:2.7.7.6

GO:0003899

sp|Q86TZ1|TTC6_HUMAN
Tetratricopeptide repeat protein 6
Search

TTC6

0.89	Tetratricopeptide repeat protein 6

sp|Q86U02|CN165_HUMAN
Putative uncharacterized protein encoded by LINC00596
Search

0.54	GO:0048741	skeletal muscle fiber development
0.43	GO:0065007	biological regulation
0.42	GO:0030574	collagen catabolic process
0.40	GO:0019538	protein metabolic process
0.39	GO:0006851	mitochondrial calcium ion transmembrane transport
0.39	GO:0023052	signaling
0.39	GO:0097242	amyloid-beta clearance
0.39	GO:0007154	cell communication
0.39	GO:0070509	calcium ion import
0.38	GO:0050896	response to stimulus

0.41	GO:0005515	protein binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0008270	zinc ion binding
0.39	GO:0004888	transmembrane signaling receptor activity
0.39	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity
0.39	GO:0003676	nucleic acid binding
0.38	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0008484	sulfuric ester hydrolase activity
0.37	GO:0016301	kinase activity

0.42	GO:0044421	extracellular region part
0.41	GO:0005829	cytosol
0.39	GO:0043234	protein complex
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0005887	integral component of plasma membrane
0.37	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005929	cilium
0.36	GO:0031975	envelope
0.36	GO:0012505	endomembrane system

0.39	EC:1.3.1.38	GO:0019166
0.35	KEGG:R01529	GO:0004750

sp|Q86U06|RBM23_HUMAN
Probable RNA-binding protein 23
Search

RBM23

0.97	RNA binding motif protein 23

0.70	GO:0006397	mRNA processing
0.33	GO:0055085	transmembrane transport

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.33	GO:0022857	transmembrane transporter activity

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q86U10|LPP60_HUMAN
60 kDa lysophospholipase
Search

ASPG

0.43	Lysophospholipase

0.56	GO:0006520	cellular amino acid metabolic process
0.46	GO:0072329	monocarboxylic acid catabolic process
0.44	GO:1901565	organonitrogen compound catabolic process
0.41	GO:0043603	cellular amide metabolic process
0.38	GO:0016042	lipid catabolic process
0.35	GO:0007018	microtubule-based movement
0.34	GO:0006644	phospholipid metabolic process
0.34	GO:0046394	carboxylic acid biosynthetic process
0.33	GO:1901566	organonitrogen compound biosynthetic process

0.79	GO:0004067	asparaginase activity
0.41	GO:0004622	lysophospholipase activity
0.40	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:3.5.1.1

GO:0004067

sp|Q86U17|SPA11_HUMAN
Serpin A11
Search

0.78	Thyroxine-binding globulin

0.53	GO:0010951	negative regulation of endopeptidase activity
0.47	GO:0070327	thyroid hormone transport
0.37	GO:0008211	glucocorticoid metabolic process
0.37	GO:0007283	spermatogenesis
0.36	GO:0006508	proteolysis
0.36	GO:0043434	response to peptide hormone
0.36	GO:0061107	seminal vesicle development
0.35	GO:0034097	response to cytokine
0.34	GO:0033189	response to vitamin A
0.34	GO:0051412	response to corticosterone

0.54	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0008289	lipid binding
0.37	GO:0032190	acrosin binding
0.37	GO:0050997	quaternary ammonium group binding
0.36	GO:0008233	peptidase activity
0.36	GO:0002020	protease binding
0.36	GO:0070405	ammonium ion binding
0.35	GO:0033293	monocarboxylic acid binding
0.34	GO:0015349	thyroid hormone transmembrane transporter activity
0.34	GO:0042562	hormone binding

0.73	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.37	GO:0036025	protein C inhibitor-TMPRSS11E complex
0.37	GO:0097182	protein C inhibitor-coagulation factor Xa complex
0.37	GO:0097183	protein C inhibitor-coagulation factor XI complex
0.37	GO:0097181	protein C inhibitor-coagulation factor V complex
0.37	GO:0036030	protein C inhibitor-plasma kallikrein complex
0.37	GO:0036028	protein C inhibitor-thrombin complex
0.37	GO:0036029	protein C inhibitor-KLK3 complex
0.37	GO:0036024	protein C inhibitor-TMPRSS7 complex

0.36

GO:0008233

sp|Q86U28|ISCA2_HUMAN
Iron-sulfur cluster assembly 2 homolog, mitochondrial
Search

ISCA2

0.95	Iron-sulfur cluster assembly 2 like protein, mitochondrial

0.77	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.44	GO:0031163	metallo-sulfur cluster assembly
0.42	GO:0006790	sulfur compound metabolic process
0.41	GO:0051188	cofactor biosynthetic process
0.33	GO:0009607	response to biotic stimulus
0.32	GO:0044281	small molecule metabolic process

0.64	GO:0051540	metal cluster binding
0.61	GO:0005198	structural molecule activity
0.55	GO:0048037	cofactor binding
0.41	GO:0005506	iron ion binding
0.33	GO:0005515	protein binding

0.44	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q86U37|CN023_HUMAN
Uncharacterized protein encoded by LINC01551
Search

sp|Q86U38|NOP9_HUMAN
Nucleolar protein 9
Search

NOP9

0.71	Nucleolar protein 9

0.59

GO:0003723

RNA binding

sp|Q86U42|PABP2_HUMAN
Polyadenylate-binding protein 2
Search

PABPN1

0.81	Polyadenylate-binding protein nuclear 1

0.86	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
0.48	GO:0071222	cellular response to lipopolysaccharide
0.47	GO:0016973	poly(A)+ mRNA export from nucleus
0.47	GO:0000165	MAPK cascade
0.44	GO:0042981	regulation of apoptotic process
0.43	GO:0006915	apoptotic process
0.41	GO:0043069	negative regulation of programmed cell death
0.39	GO:0031124	mRNA 3'-end processing
0.38	GO:0043631	RNA polyadenylation
0.36	GO:0038034	signal transduction in absence of ligand

0.59	GO:0003723	RNA binding
0.46	GO:0070063	RNA polymerase binding
0.42	GO:0097718	disordered domain specific binding
0.40	GO:0046982	protein heterodimerization activity
0.40	GO:0042802	identical protein binding
0.38	GO:0043621	protein self-association

0.50	GO:0042405	nuclear inclusion body
0.43	GO:0097136	Bcl-2 family protein complex
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0016607	nuclear speck
0.35	GO:0005741	mitochondrial outer membrane

sp|Q86U44|MTA70_HUMAN
N6-adenosine-methyltransferase 70 kDa subunit
Search

METTL3

0.94	Spalt like transcription factor 2

0.79	GO:0080009	mRNA methylation
0.65	GO:1990729	primary miRNA modification
0.62	GO:1903679	positive regulation of cap-independent translational initiation
0.57	GO:0034644	cellular response to UV
0.54	GO:0000398	mRNA splicing, via spliceosome
0.49	GO:0098508	endothelial to hematopoietic transition
0.48	GO:1902036	regulation of hematopoietic stem cell differentiation
0.48	GO:0006974	cellular response to DNA damage stimulus
0.47	GO:0045746	negative regulation of Notch signaling pathway
0.42	GO:0042981	regulation of apoptotic process

0.86	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
0.54	GO:1904047	S-adenosyl-L-methionine binding
0.53	GO:0003729	mRNA binding
0.52	GO:0046982	protein heterodimerization activity
0.36	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.62	GO:0036396	RNA N6-methyladenosine methyltransferase complex
0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm

0.86

EC:2.1.1.62

GO:0016422

sp|Q86U70|LDB1_HUMAN
LIM domain-binding protein 1
Search

LDB1

0.96	LIM domain-binding protein 1

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0046985	positive regulation of hemoglobin biosynthetic process
0.57	GO:0045647	negative regulation of erythrocyte differentiation
0.57	GO:0043973	histone H3-K4 acetylation
0.56	GO:0021702	cerebellar Purkinje cell differentiation
0.55	GO:0010669	epithelial structure maintenance
0.55	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
0.55	GO:0001702	gastrulation with mouth forming second
0.55	GO:0035019	somatic stem cell population maintenance
0.54	GO:0051893	regulation of focal adhesion assembly

0.86	GO:0030274	LIM domain binding
0.75	GO:0000989	transcription factor activity, transcription factor binding
0.54	GO:0001102	RNA polymerase II activating transcription factor binding
0.54	GO:0043621	protein self-association
0.54	GO:0001158	enhancer sequence-specific DNA binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0003682	chromatin binding
0.48	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.52	GO:0031252	cell leading edge
0.49	GO:0005667	transcription factor complex
0.48	GO:0000785	chromatin
0.46	GO:0043233	organelle lumen

sp|Q86U86|PB1_HUMAN
Protein polybromo-1
Search

PBRM1

0.92	Polybromo 1

0.78	GO:0006338	chromatin remodeling
0.68	GO:0008285	negative regulation of cell proliferation
0.39	GO:0001890	placenta development
0.39	GO:0007507	heart development

0.77	GO:0003682	chromatin binding
0.55	GO:0003677	DNA binding

0.83	GO:0016586	RSC-type complex
0.61	GO:0005654	nucleoplasm
0.38	GO:0000776	kinetochore
0.30	GO:0031224	intrinsic component of membrane

sp|Q86U90|YRDC_HUMAN
YrdC domain-containing protein, mitochondrial
Search

YRDC

0.96	YrdC domain-containing protein, mitochondrial

0.58	GO:0051051	negative regulation of transport
0.47	GO:0002949	tRNA threonylcarbamoyladenosine modification
0.46	GO:0006450	regulation of translational fidelity

0.74	GO:0003725	double-stranded RNA binding
0.45	GO:0000049	tRNA binding
0.42	GO:0016779	nucleotidyltransferase activity
0.34	GO:0005515	protein binding

0.37	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.42

GO:0016779

sp|Q86UA1|PRP39_HUMAN
Pre-mRNA-processing factor 39
Search

PRPF39

0.89	Pre-mRNA-processing factor 39

0.61	GO:0006396	RNA processing
0.43	GO:0022618	ribonucleoprotein complex assembly
0.43	GO:0016071	mRNA metabolic process

0.49	GO:0030627	pre-mRNA 5'-splice site binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0097367	carbohydrate derivative binding

0.47	GO:0000243	commitment complex
0.46	GO:0071004	U2-type prespliceosome
0.46	GO:0005685	U1 snRNP

sp|Q86UA6|RIP_HUMAN
RPA-interacting protein
Search

RPAIN

0.95	RPA interacting protein alpha

0.47	GO:0009411	response to UV
0.47	GO:0006606	protein import into nucleus
0.44	GO:0006261	DNA-dependent DNA replication
0.42	GO:0006310	DNA recombination
0.42	GO:0006281	DNA repair

0.45	GO:0032403	protein complex binding
0.39	GO:0046872	metal ion binding

0.82	GO:0001650	fibrillar center
0.49	GO:0016605	PML body
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q86UB2|BIVM_HUMAN
Basic immunoglobulin-like variable motif-containing protein
Search

BIVM

0.97	Basic, immunoglobulin-like variable motif containing

0.52

GO:0006295

nucleotide-excision repair, DNA incision, 3'-to lesion

0.45	GO:0003697	single-stranded DNA binding
0.45	GO:0004520	endodeoxyribonuclease activity

0.58	GO:0005634	nucleus
0.58	GO:0005615	extracellular space
0.46	GO:0005737	cytoplasm

sp|Q86UB9|TM135_HUMAN
Transmembrane protein 135
Search

TMEM135

0.97	Transmembrane protein 135

0.58	GO:0090140	regulation of mitochondrial fission
0.57	GO:0032094	response to food
0.53	GO:0009409	response to cold
0.38	GO:0007031	peroxisome organization
0.36	GO:0010918	positive regulation of mitochondrial membrane potential
0.36	GO:0010884	positive regulation of lipid storage
0.35	GO:0008340	determination of adult lifespan
0.34	GO:0010628	positive regulation of gene expression

0.54	GO:0005811	lipid droplet
0.53	GO:0042579	microbody
0.45	GO:0005739	mitochondrion
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.37	GO:0031967	organelle envelope
0.30	GO:0044425	membrane part

sp|Q86UC2|RSPH3_HUMAN
Radial spoke head protein 3 homolog
Search

RSPH3

0.96	Flagellar radial spoke protein 3

0.48

GO:0005515

protein binding

0.68	GO:0042995	cell projection
0.65	GO:0005856	cytoskeleton
0.47	GO:0005737	cytoplasm

sp|Q86UD0|SAPC2_HUMAN
Suppressor APC domain-containing protein 2
Search

SAPCD2

0.96	Suppressor APC domain-containing protein 2

0.88	GO:1904777	negative regulation of protein localization to cell cortex
0.86	GO:0098725	symmetric cell division
0.82	GO:0090175	regulation of establishment of planar polarity
0.82	GO:0000132	establishment of mitotic spindle orientation
0.79	GO:0008284	positive regulation of cell proliferation
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation

0.39	GO:0005515	protein binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.85	GO:0045179	apical cortex
0.80	GO:0043296	apical junction complex
0.73	GO:0005730	nucleolus
0.68	GO:0005829	cytosol
0.49	GO:0016324	apical plasma membrane
0.49	GO:0070160	occluding junction
0.30	GO:0016021	integral component of membrane

0.34

EC:3.1.3.48

GO:0004725

sp|Q86UD1|OAF_HUMAN
Out at first protein homolog
Search

OAF

0.97	Out at first protein homolog

0.45	GO:0016321	female meiosis chromosome segregation
0.44	GO:0007275	multicellular organism development
0.44	GO:0043922	negative regulation by host of viral transcription
0.40	GO:0006366	transcription by RNA polymerase II
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II

0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.62	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q86UD3|MARH3_HUMAN
E3 ubiquitin-protein ligase MARCH3
Search

MARCH3

0.91	Membrane associated ring-CH-type finger 3

0.45	GO:0016567	protein ubiquitination
0.40	GO:0006897	endocytosis
0.37	GO:0030097	hemopoiesis
0.33	GO:0000398	mRNA splicing, via spliceosome

0.63	GO:0008270	zinc ion binding
0.53	GO:0016874	ligase activity
0.43	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0003723	RNA binding

0.52	GO:0005764	lysosome
0.52	GO:0031410	cytoplasmic vesicle
0.49	GO:0012505	endomembrane system
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0012506	vesicle membrane
0.37	GO:0044446	intracellular organelle part
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:6	GO:0016874
0.43	KEGG:R03876	GO:0004842

sp|Q86UD4|ZN329_HUMAN
Zinc finger protein 329
Search

0.70	zinc finger protein 329

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:0030097	hemopoiesis
0.33	GO:0035556	intracellular signal transduction

0.51	GO:0003676	nucleic acid binding
0.48	GO:0046872	metal ion binding
0.43	GO:0003700	DNA binding transcription factor activity
0.30	GO:0005515	protein binding

0.41	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q86UD5|SL9B2_HUMAN
Mitochondrial sodium/hydrogen exchanger 9B2
Search

SLC9B2

0.94	Mitochondrial sodium/hydrogen exchanger NHA2

0.72	GO:0006814	sodium ion transport
0.62	GO:1902600	hydrogen ion transmembrane transport
0.55	GO:2001206	positive regulation of osteoclast development
0.53	GO:0030317	flagellated sperm motility
0.53	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.47	GO:0072583	clathrin-dependent endocytosis
0.34	GO:0007018	microtubule-based movement
0.34	GO:0051453	regulation of intracellular pH
0.34	GO:0007338	single fertilization
0.33	GO:0055114	oxidation-reduction process

0.74	GO:0015299	solute:proton antiporter activity
0.50	GO:0015491	cation:cation antiporter activity
0.48	GO:0015081	sodium ion transmembrane transporter activity
0.47	GO:0042802	identical protein binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding

0.54	GO:0097228	sperm principal piece
0.54	GO:0030672	synaptic vesicle membrane
0.52	GO:0016323	basolateral plasma membrane
0.50	GO:0010008	endosome membrane
0.44	GO:0031966	mitochondrial membrane
0.38	GO:0030054	cell junction
0.35	GO:0019866	organelle inner membrane
0.35	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0016491

sp|Q86UD7|TBC26_HUMAN
TBC1 domain family member 26
Search

0.81	USP6 N-terminal like

0.75	GO:0031338	regulation of vesicle fusion
0.74	GO:0090630	activation of GTPase activity
0.63	GO:0035526	retrograde transport, plasma membrane to Golgi
0.62	GO:0006886	intracellular protein transport
0.61	GO:0048227	plasma membrane to endosome transport
0.61	GO:1903358	regulation of Golgi organization
0.56	GO:0007030	Golgi organization
0.51	GO:0019068	virion assembly
0.44	GO:0016579	protein deubiquitination
0.41	GO:1902017	regulation of cilium assembly

0.76	GO:0017137	Rab GTPase binding
0.72	GO:0005096	GTPase activator activity
0.44	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.36	GO:0005516	calmodulin binding
0.36	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0003676	nucleic acid binding

0.61	GO:0012505	endomembrane system
0.55	GO:0031410	cytoplasmic vesicle
0.47	GO:0005886	plasma membrane
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0005764	lysosome
0.35	GO:0098805	whole membrane
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.44

EC:3.4.19.12

GO:0036459

sp|Q86UE3|ZN546_HUMAN
Zinc finger protein 546
Search

0.66	Zinc finger protein 546

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.30	GO:0044237	cellular metabolic process
0.30	GO:0006807	nitrogen compound metabolic process
0.30	GO:1901360	organic cyclic compound metabolic process
0.30	GO:1901576	organic substance biosynthetic process
0.30	GO:0044238	primary metabolic process
0.30	GO:0043170	macromolecule metabolic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.30	GO:0140110	transcription regulator activity

0.45	GO:0005622	intracellular
0.30	GO:0044425	membrane part
0.30	GO:0043226	organelle

sp|Q86UE4|LYRIC_HUMAN
Protein LYRIC
Search

MTDH

0.97	Metadherin a

0.84	GO:0045766	positive regulation of angiogenesis
0.84	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.78	GO:0043066	negative regulation of apoptotic process
0.61	GO:0031663	lipopolysaccharide-mediated signaling pathway
0.60	GO:0051897	positive regulation of protein kinase B signaling
0.59	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.57	GO:0010508	positive regulation of autophagy
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0070830	bicellular tight junction assembly

0.62	GO:0051059	NF-kappaB binding
0.59	GO:0001085	RNA polymerase II transcription factor binding
0.57	GO:0003713	transcription coactivator activity
0.55	GO:0003725	double-stranded RNA binding

0.60	GO:0001650	fibrillar center
0.57	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0016604	nuclear body
0.53	GO:0005783	endoplasmic reticulum
0.53	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.50	GO:0031984	organelle subcompartment
0.44	GO:0046581	intercellular canaliculus
0.42	GO:0016324	apical plasma membrane
0.42	GO:0005923	bicellular tight junction
0.40	GO:0031965	nuclear membrane

sp|Q86UE6|LRRT1_HUMAN
Leucine-rich repeat transmembrane neuronal protein 1
Search

LRRTM1

0.97	Leucine-rich repeat transmembrane neuronal protein 1

0.54	GO:0051965	positive regulation of synapse assembly
0.52	GO:0046426	negative regulation of JAK-STAT cascade
0.52	GO:0002091	negative regulation of receptor internalization
0.50	GO:0035418	protein localization to synapse
0.50	GO:0035640	exploration behavior
0.50	GO:0060291	long-term synaptic potentiation
0.50	GO:0006469	negative regulation of protein kinase activity
0.49	GO:0019221	cytokine-mediated signaling pathway
0.49	GO:1902004	positive regulation of amyloid-beta formation
0.48	GO:0007626	locomotory behavior

0.51	GO:0004860	protein kinase inhibitor activity
0.40	GO:0042802	identical protein binding

0.53	GO:0030426	growth cone
0.51	GO:0030424	axon
0.47	GO:0005783	endoplasmic reticulum
0.41	GO:0045211	postsynaptic membrane
0.40	GO:0030054	cell junction
0.39	GO:0060076	excitatory synapse
0.36	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q86UE8|TLK2_HUMAN
Serine/threonine-protein kinase tousled-like 2
Search

TLK2

0.76	Tousled like kinase 2

0.62	GO:0006468	protein phosphorylation
0.55	GO:0071480	cellular response to gamma radiation
0.55	GO:0001672	regulation of chromatin assembly or disassembly
0.55	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.52	GO:0018209	peptidyl-serine modification
0.48	GO:0007059	chromosome segregation
0.45	GO:0006974	cellular response to DNA damage stimulus
0.44	GO:0035556	intracellular signal transduction
0.36	GO:0016569	covalent chromatin modification
0.35	GO:0010507	negative regulation of autophagy

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005882	intermediate filament

0.69

GO:0004674

sp|Q86UF1|TSN33_HUMAN
Tetraspanin-33
Search

TSPAN33

0.57	Tetraspanin

0.54	GO:0072659	protein localization to plasma membrane
0.49	GO:0051604	protein maturation
0.46	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0007275	multicellular organism development
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0072594	establishment of protein localization to organelle
0.32	GO:0016255	attachment of GPI anchor to protein

0.49	GO:0019899	enzyme binding
0.35	GO:0004888	transmembrane signaling receptor activity

0.56	GO:0097197	tetraspanin-enriched microdomain
0.50	GO:0009986	cell surface
0.44	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus
0.32	GO:0042765	GPI-anchor transamidase complex

sp|Q86UF2|CTGE6_HUMAN
cTAGE family member 6
Search

0.83	Cutaneous T-cell lymphoma-associated antigen 1

0.30

GO:0044425

membrane part

sp|Q86UF4|CC190_HUMAN
Coiled-coil domain-containing protein 190
Search

CCDC190

0.62	Coiled-coil domain-containing protein 190

sp|Q86UG4|SO6A1_HUMAN
Solute carrier organic anion transporter family member 6A1
Search

0.61	Testis-specific transporter TST-2

0.58	GO:0043252	sodium-independent organic anion transport
0.55	GO:0055085	transmembrane transport
0.39	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development
0.35	GO:0043312	neutrophil degranulation
0.32	GO:0043043	peptide biosynthetic process
0.31	GO:0044267	cellular protein metabolic process
0.31	GO:0010467	gene expression
0.31	GO:0009059	macromolecule biosynthetic process

0.58	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.32	GO:0003735	structural constituent of ribosome

0.54	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0035579	specific granule membrane
0.36	GO:0035577	azurophil granule membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

sp|Q86UK0|ABCAC_HUMAN
ATP-binding cassette sub-family A member 12
Search

ABCA12

0.93	ATP-binding cassette sub-family A member 12

0.74	GO:0006869	lipid transport
0.71	GO:0043129	surfactant homeostasis
0.71	GO:0010875	positive regulation of cholesterol efflux
0.70	GO:2000010	positive regulation of protein localization to cell surface
0.69	GO:0061436	establishment of skin barrier
0.69	GO:0031424	keratinization
0.68	GO:0048286	lung alveolus development
0.66	GO:0072659	protein localization to plasma membrane
0.66	GO:0045055	regulated exocytosis
0.65	GO:0055088	lipid homeostasis

0.73	GO:0034191	apolipoprotein A-I receptor binding
0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.62	GO:0005319	lipid transporter activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.33	GO:0034188	apolipoprotein A-I receptor activity

0.72	GO:0097209	epidermal lamellar body
0.56	GO:0005829	cytosol
0.51	GO:0031966	mitochondrial membrane
0.51	GO:0019866	organelle inner membrane
0.47	GO:0005886	plasma membrane
0.32	GO:0030054	cell junction
0.32	GO:0005794	Golgi apparatus
0.32	GO:0001726	ruffle
0.31	GO:0045177	apical part of cell
0.31	GO:0010008	endosome membrane

sp|Q86UK5|LBN_HUMAN
Limbin
Search

EVC2

0.97	EvC ciliary complex subunit 2

0.84

GO:0007224

smoothened signaling pathway

0.78	GO:0060170	ciliary membrane
0.61	GO:0098797	plasma membrane protein complex
0.57	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q86UK7|ZN598_HUMAN
E3 ubiquitin-protein ligase ZNF598
Search

ZNF598

0.86	LOW QUALITY PROTEIN: zinc finger protein 598

0.41	GO:0072344	rescue of stalled ribosome
0.40	GO:0006513	protein monoubiquitination

0.51	GO:0003676	nucleic acid binding
0.39	GO:0061630	ubiquitin protein ligase activity
0.39	GO:0043022	ribosome binding
0.35	GO:0016874	ligase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.35

GO:0016874

sp|Q86UL3|GPAT4_HUMAN
Glycerol-3-phosphate acyltransferase 4
Search

GPAT4

0.93	Glycerol-3-phosphate acyltransferase 4

0.59	GO:0002071	glandular epithelial cell maturation
0.57	GO:0046339	diacylglycerol metabolic process
0.55	GO:0006656	phosphatidylcholine biosynthetic process
0.54	GO:0040014	regulation of multicellular organism growth
0.54	GO:0019432	triglyceride biosynthetic process
0.53	GO:0007595	lactation
0.50	GO:0035383	thioester metabolic process
0.47	GO:0006631	fatty acid metabolic process
0.45	GO:0006732	coenzyme metabolic process
0.39	GO:0016024	CDP-diacylglycerol biosynthetic process

0.62

GO:0016746

transferase activity, transferring acyl groups

0.49	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.62

GO:0016746

sp|Q86UL8|MAGI2_HUMAN
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Search

MAGI2

0.91	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

0.59	GO:0032926	negative regulation of activin receptor signaling pathway
0.58	GO:0007165	signal transduction
0.57	GO:0043113	receptor clustering
0.57	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.56	GO:0002092	positive regulation of receptor internalization
0.56	GO:2000809	positive regulation of synaptic vesicle clustering
0.55	GO:0051898	negative regulation of protein kinase B signaling
0.55	GO:0097104	postsynaptic membrane assembly
0.50	GO:0072015	glomerular visceral epithelial cell development
0.50	GO:0071850	mitotic cell cycle arrest

0.76	GO:0032947	protein complex scaffold activity
0.60	GO:0070699	type II activin receptor binding
0.59	GO:0031697	beta-1 adrenergic receptor binding
0.56	GO:0046332	SMAD binding
0.53	GO:0019902	phosphatase binding
0.51	GO:0016301	kinase activity
0.46	GO:0004871	signal transducer activity
0.36	GO:0019894	kinesin binding
0.35	GO:0032403	protein complex binding
0.32	GO:0008270	zinc ion binding

0.76	GO:0005923	bicellular tight junction
0.52	GO:0097458	neuron part
0.51	GO:0036057	slit diaphragm
0.49	GO:0120038	plasma membrane bounded cell projection part
0.48	GO:0032279	asymmetric synapse
0.48	GO:0099572	postsynaptic specialization
0.47	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.39	GO:0005770	late endosome

sp|Q86UN2|R4RL1_HUMAN
Reticulon-4 receptor-like 1
Search

RTN4RL1

0.97	Reticulon 4 receptor like 1

0.76	GO:0022038	corpus callosum development
0.73	GO:0048681	negative regulation of axon regeneration
0.60	GO:0046426	negative regulation of JAK-STAT cascade
0.57	GO:0006469	negative regulation of protein kinase activity
0.56	GO:0019221	cytokine-mediated signaling pathway
0.46	GO:0048922	posterior lateral line neuromast deposition
0.41	GO:0031103	axon regeneration
0.39	GO:0006501	C-terminal protein lipidation

0.75	GO:0035374	chondroitin sulfate binding
0.68	GO:0008201	heparin binding
0.58	GO:0004860	protein kinase inhibitor activity
0.56	GO:0004872	receptor activity
0.39	GO:0005515	protein binding

0.70	GO:0046658	anchored component of plasma membrane
0.65	GO:0009986	cell surface
0.46	GO:0043204	perikaryon
0.44	GO:0045121	membrane raft
0.43	GO:0098552	side of membrane
0.41	GO:0070062	extracellular exosome
0.41	GO:0042995	cell projection
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q86UN3|R4RL2_HUMAN
Reticulon-4 receptor-like 2
Search

0.82	Reticulon 4 receptor like 2

0.81	GO:0022038	corpus callosum development
0.77	GO:0010977	negative regulation of neuron projection development
0.63	GO:0046426	negative regulation of JAK-STAT cascade
0.61	GO:0048679	regulation of axon regeneration
0.60	GO:0006469	negative regulation of protein kinase activity
0.60	GO:1903035	negative regulation of response to wounding
0.59	GO:0019221	cytokine-mediated signaling pathway
0.58	GO:0032102	negative regulation of response to external stimulus
0.46	GO:0031103	axon regeneration
0.42	GO:0006501	C-terminal protein lipidation

0.63	GO:0035374	chondroitin sulfate binding
0.61	GO:0004860	protein kinase inhibitor activity
0.59	GO:0004872	receptor activity
0.58	GO:0008201	heparin binding
0.41	GO:0005515	protein binding

0.74	GO:0046658	anchored component of plasma membrane
0.69	GO:0009986	cell surface
0.49	GO:0043204	perikaryon
0.47	GO:0045121	membrane raft
0.46	GO:0098552	side of membrane
0.45	GO:0030425	dendrite
0.45	GO:0030424	axon
0.44	GO:0070062	extracellular exosome
0.41	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q86UN6|AKA28_HUMAN
A-kinase anchor protein 14
Search

AKAP14

0.90	A-kinase anchoring protein 14

0.47	GO:0016310	phosphorylation
0.41	GO:0007283	spermatogenesis

0.80	GO:0034237	protein kinase A regulatory subunit binding
0.48	GO:0016301	kinase activity

0.77	GO:0005952	cAMP-dependent protein kinase complex
0.75	GO:0005930	axoneme
0.43	GO:0035686	sperm fibrous sheath

sp|Q86UP0|CAD24_HUMAN
Cadherin-24
Search

0.55	Cadherin 8

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.30	GO:0034332	adherens junction organization

0.70	GO:0005509	calcium ion binding
0.30	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.30	GO:0030054	cell junction
0.30	GO:0044425	membrane part

sp|Q86UP2|KTN1_HUMAN
Kinectin
Search

KTN1

0.91	Kinectin 1 (Kinesin receptor)

0.74	GO:0007018	microtubule-based movement
0.50	GO:0015031	protein transport
0.37	GO:0043687	post-translational protein modification

0.85	GO:0019894	kinesin binding
0.60	GO:0045296	cadherin binding
0.34	GO:0003723	RNA binding

0.61	GO:0005783	endoplasmic reticulum
0.54	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.52	GO:0031984	organelle subcompartment
0.35	GO:0043233	organelle lumen
0.35	GO:0005887	integral component of plasma membrane
0.32	GO:0070382	exocytic vesicle

sp|Q86UP3|ZFHX4_HUMAN
Zinc finger homeobox protein 4
Search

ZFHX4

0.86	LOW QUALITY PROTEIN: zinc finger homeobox protein 4

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding

0.60

GO:0005634

nucleus

sp|Q86UP6|CUZD1_HUMAN
CUB and zona pellucida-like domain-containing protein 1
Search

CUZD1

0.95	CUB and zona pellucida like domains 1

0.49	GO:0032023	trypsinogen activation
0.44	GO:0006931	substrate-dependent cell migration, cell attachment to substrate
0.40	GO:0008283	cell proliferation
0.40	GO:0007565	female pregnancy
0.39	GO:0009755	hormone-mediated signaling pathway
0.38	GO:0051301	cell division
0.38	GO:0007049	cell cycle
0.35	GO:0006955	immune response
0.35	GO:0006898	receptor-mediated endocytosis

0.35	GO:0005044	scavenger receptor activity
0.35	GO:0001871	pattern binding
0.34	GO:0030246	carbohydrate binding

0.47	GO:0042589	zymogen granule membrane
0.43	GO:0030658	transport vesicle membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q86UP8|GTD2A_HUMAN
General transcription factor II-I repeat domain-containing protein 2A
Search

0.75	GTF2I repeat domain containing 2B

0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process

0.55

GO:0003677

DNA binding

0.61

GO:0005634

nucleus

sp|Q86UP9|LHPL3_HUMAN
Lipoma HMGIC fusion partner-like 3 protein
Search

LHFPL3

0.86	LHFPL tetraspan subfamily member 3

0.30

GO:0044425

membrane part

sp|Q86UQ0|ZN589_HUMAN
Zinc finger protein 589
Search

ZNF589

0.97	LOW QUALITY PROTEIN: zinc finger protein 589

0.54	GO:2001141	regulation of RNA biosynthetic process
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.41	GO:0051253	negative regulation of RNA metabolic process
0.41	GO:0010558	negative regulation of macromolecule biosynthetic process
0.41	GO:0031327	negative regulation of cellular biosynthetic process
0.40	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.40	GO:0051873	killing by host of symbiont cells
0.39	GO:0044130	negative regulation of growth of symbiont in host
0.39	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.45	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.39	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0005524	ATP binding

0.43	GO:0005622	intracellular
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0043227	membrane-bounded organelle
0.39	GO:0044422	organelle part
0.36	GO:0012505	endomembrane system
0.36	GO:0005576	extracellular region
0.36	GO:0043228	non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

sp|Q86UQ4|ABCAD_HUMAN
ATP-binding cassette sub-family A member 13
Search

ABCA13

0.86	LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 13

0.57	GO:0006869	lipid transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0045055	regulated exocytosis
0.44	GO:0002283	neutrophil activation involved in immune response
0.44	GO:0002446	neutrophil mediated immunity
0.40	GO:0043129	surfactant homeostasis
0.40	GO:0010875	positive regulation of cholesterol efflux
0.40	GO:2000010	positive regulation of protein localization to cell surface
0.40	GO:0008544	epidermis development
0.40	GO:0061436	establishment of skin barrier

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0034191	apolipoprotein A-I receptor binding
0.38	GO:0005319	lipid transporter activity

0.45	GO:0035577	azurophil granule membrane
0.40	GO:0097209	epidermal lamellar body
0.38	GO:0005886	plasma membrane
0.36	GO:0005829	cytosol
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.32	GO:0005768	endosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q86UQ5|GTSC1_HUMAN
Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein
Search

0.22	Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein

0.30

GO:0044425

membrane part

sp|Q86UQ8|NFE4_HUMAN
Transcription factor NF-E4
Search

NFE4

0.95	Transcription factor NF-E4

0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.69	GO:0006461	protein complex assembly
0.58	GO:0006351	transcription, DNA-templated

0.79	GO:0000987	proximal promoter sequence-specific DNA binding
0.75	GO:0042803	protein homodimerization activity
0.61	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.59	GO:0043234	protein complex

sp|Q86UR1|NOXA1_HUMAN
NADPH oxidase activator 1
Search

NOXA1

0.90	NADPH oxidase activator 1

0.75	GO:0006801	superoxide metabolic process
0.69	GO:0060263	regulation of respiratory burst
0.68	GO:0010310	regulation of hydrogen peroxide metabolic process
0.57	GO:0043085	positive regulation of catalytic activity
0.35	GO:0007015	actin filament organization
0.35	GO:0007155	cell adhesion

0.68	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.66	GO:0048365	Rac GTPase binding
0.62	GO:0017124	SH3 domain binding

0.85	GO:0043020	NADPH oxidase complex
0.38	GO:0005829	cytosol

sp|Q86UR5|RIMS1_HUMAN
Regulating synaptic membrane exocytosis protein 1
Search

RIMS1

0.82	Regulating synaptic membrane exocytosis protein 1

0.77	GO:0006887	exocytosis
0.57	GO:1903861	positive regulation of dendrite extension
0.53	GO:0046907	intracellular transport
0.51	GO:0034613	cellular protein localization
0.49	GO:2000300	regulation of synaptic vesicle exocytosis
0.49	GO:0015031	protein transport
0.48	GO:0097480	establishment of synaptic vesicle localization
0.48	GO:0099504	synaptic vesicle cycle
0.48	GO:0099003	vesicle-mediated transport in synapse
0.48	GO:0099643	signal release from synapse

0.81	GO:0017137	Rab GTPase binding
0.50	GO:0046872	metal ion binding
0.48	GO:0044325	ion channel binding
0.36	GO:0030695	GTPase regulator activity
0.35	GO:0003723	RNA binding
0.35	GO:0017124	SH3 domain binding
0.34	GO:0019901	protein kinase binding

0.83	GO:0048786	presynaptic active zone
0.40	GO:0042734	presynaptic membrane
0.38	GO:0005622	intracellular
0.38	GO:0030054	cell junction
0.37	GO:0060077	inhibitory synapse
0.36	GO:0014069	postsynaptic density
0.35	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

sp|Q86US8|EST1A_HUMAN
Telomerase-binding protein EST1A
Search

SMG6

0.92	Smg-6 homolog, nonsense mediated mRNA decay factor

0.85	GO:1904354	negative regulation of telomere capping
0.83	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.67	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.62	GO:0007004	telomere maintenance via telomerase
0.60	GO:0043487	regulation of RNA stability
0.58	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.56	GO:0051028	mRNA transport
0.55	GO:0006405	RNA export from nucleus
0.48	GO:0043009	chordate embryonic development
0.43	GO:0010467	gene expression

0.85	GO:0070034	telomerase RNA binding
0.85	GO:0070182	DNA polymerase binding
0.79	GO:0042162	telomeric DNA binding
0.71	GO:0043021	ribonucleoprotein complex binding
0.68	GO:0004521	endoribonuclease activity

0.85	GO:0000333	telomerase catalytic core complex
0.82	GO:0035145	exon-exon junction complex
0.70	GO:0005730	nucleolus
0.66	GO:0005829	cytosol

sp|Q86UT5|NHRF4_HUMAN
Na(+)/H(+) exchange regulatory cofactor NHE-RF4
Search

PDZD3

0.97	PDZ domain-containing protein 2 variant 1

0.87	GO:0031283	negative regulation of guanylate cyclase activity
0.86	GO:0007168	receptor guanylyl cyclase signaling pathway
0.58	GO:0006811	ion transport
0.40	GO:0019934	cGMP-mediated signaling
0.39	GO:0006833	water transport
0.36	GO:0009636	response to toxic substance
0.34	GO:0016567	protein ubiquitination
0.34	GO:0023051	regulation of signaling
0.33	GO:0006508	proteolysis

0.87	GO:0010852	cyclase inhibitor activity
0.86	GO:0030249	guanylate cyclase regulator activity
0.74	GO:0004857	enzyme inhibitor activity
0.68	GO:1990381	ubiquitin-specific protease binding
0.64	GO:0008022	protein C-terminus binding
0.39	GO:0008200	ion channel inhibitor activity
0.38	GO:0001784	phosphotyrosine residue binding
0.35	GO:0004871	signal transducer activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0004842	ubiquitin-protein transferase activity

0.69	GO:0035003	subapical complex
0.65	GO:0005903	brush border
0.62	GO:0045177	apical part of cell
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.32	GO:0042597	periplasmic space
0.30	GO:0016021	integral component of membrane

0.34	EC:3.6.1.3	GO:0016887
0.34	KEGG:R03876	GO:0004842

sp|Q86UT6|NLRX1_HUMAN
NLR family member X1
Search

NLRX1

0.97	NLR family member X1

0.77	GO:0039536	negative regulation of RIG-I signaling pathway
0.77	GO:0032688	negative regulation of interferon-beta production
0.74	GO:0032715	negative regulation of interleukin-6 production
0.73	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.72	GO:0050728	negative regulation of inflammatory response
0.63	GO:0045824	negative regulation of innate immune response
0.44	GO:0045087	innate immune response
0.39	GO:0016032	viral process
0.37	GO:0007166	cell surface receptor signaling pathway

0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005515	protein binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0016887	ATPase activity
0.35	GO:0004871	signal transducer activity

0.65	GO:0030054	cell junction
0.54	GO:0005739	mitochondrion
0.50	GO:0005886	plasma membrane
0.43	GO:0031968	organelle outer membrane
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016887

sp|Q86UT8|CCD84_HUMAN
Coiled-coil domain-containing protein 84
Search

CCDC84

0.97	Coiled-coil domain-containing protein 84

0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated

0.51	GO:0043565	sequence-specific DNA binding
0.49	GO:0003700	DNA binding transcription factor activity

0.52	GO:0005634	nucleus
0.46	GO:0034708	methyltransferase complex
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

sp|Q86UU0|BCL9L_HUMAN
B-cell CLL/lymphoma 9-like protein
Search

BCL9L

0.76	B-cell CLL/lymphoma 9 like

0.84	GO:0060070	canonical Wnt signaling pathway
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0035019	somatic stem cell population maintenance
0.56	GO:0035914	skeletal muscle cell differentiation
0.55	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.54	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0010628	positive regulation of gene expression
0.47	GO:0022604	regulation of cell morphogenesis
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.84	GO:0008013	beta-catenin binding
0.79	GO:0003713	transcription coactivator activity

0.57	GO:1990907	beta-catenin-TCF complex
0.49	GO:0005730	nucleolus
0.47	GO:0005654	nucleoplasm
0.37	GO:0005801	cis-Golgi network
0.36	GO:0005794	Golgi apparatus

sp|Q86UU1|PHLB1_HUMAN
Pleckstrin homology-like domain family B member 1
Search

PHLDB1

0.93	Pleckstrin homology like domain family B member 1

0.87	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis
0.85	GO:0010470	regulation of gastrulation
0.85	GO:0010717	regulation of epithelial to mesenchymal transition
0.81	GO:0070507	regulation of microtubule cytoskeleton organization

0.86

GO:0045180

basal cortex

sp|Q86UU5|GGN_HUMAN
Gametogenetin
Search

GGN

0.97	Gametogenetin

0.77	GO:0007276	gamete generation
0.75	GO:0006302	double-strand break repair
0.45	GO:0007566	embryo implantation
0.44	GO:0030154	cell differentiation
0.39	GO:0008104	protein localization
0.37	GO:0006461	protein complex assembly
0.34	GO:0045010	actin nucleation
0.34	GO:0006402	mRNA catabolic process
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006364	rRNA processing

0.42	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0046983	protein dimerization activity
0.34	GO:0008995	ribonuclease E activity
0.34	GO:0008092	cytoskeletal protein binding
0.33	GO:0004521	endoribonuclease activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0000287	magnesium ion binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0005201	extracellular matrix structural constituent
0.33	GO:0003723	RNA binding

0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005730	nucleolus
0.38	GO:0005635	nuclear envelope
0.37	GO:0031410	cytoplasmic vesicle
0.34	GO:0005884	actin filament
0.34	GO:0009898	cytoplasmic side of plasma membrane
0.32	GO:0009360	DNA polymerase III complex
0.32	GO:0045111	intermediate filament cytoskeleton
0.32	GO:0031968	organelle outer membrane
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.33

EC:3.2.1

GO:0004553

sp|Q86UU9|TKN4_HUMAN
Tachykinin-4
Search

TAC4

0.94	Tachykinin precursor 1

0.85	GO:0007217	tachykinin receptor signaling pathway
0.69	GO:1902093	positive regulation of flagellated sperm motility
0.56	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.55	GO:0006954	inflammatory response
0.52	GO:0007267	cell-cell signaling
0.45	GO:1904057	negative regulation of sensory perception of pain
0.45	GO:1904058	positive regulation of sensory perception of pain
0.44	GO:0008217	regulation of blood pressure
0.44	GO:0019233	sensory perception of pain
0.44	GO:0050961	detection of temperature stimulus involved in sensory perception

0.50	GO:0005102	receptor binding
0.42	GO:0030545	receptor regulator activity

0.60	GO:0005615	extracellular space
0.38	GO:0042629	mast cell granule
0.35	GO:0043025	neuronal cell body
0.35	GO:0030424	axon

sp|Q86UV5|UBP48_HUMAN
Ubiquitin carboxyl-terminal hydrolase 48
Search

USP48

0.95	Ubiquitin carboxyl-terminal hydrolase 48

0.76	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:1904888	cranial skeletal system development
0.34	GO:0051056	regulation of small GTPase mediated signal transduction
0.34	GO:0043547	positive regulation of GTPase activity

0.79	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0005096	GTPase activator activity

0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.35	GO:0045121	membrane raft
0.35	GO:0045211	postsynaptic membrane

sp|Q86UV6|TRI74_HUMAN
Tripartite motif-containing protein 74
Search

0.86	Tripartite motif-containing protein 74

0.55	GO:0070201	regulation of establishment of protein localization
0.37	GO:0016567	protein ubiquitination
0.35	GO:0039023	pronephric duct morphogenesis
0.35	GO:0070121	Kupffer's vesicle development
0.35	GO:0032402	melanosome transport
0.35	GO:0007369	gastrulation
0.34	GO:0032259	methylation
0.33	GO:0051260	protein homooligomerization
0.33	GO:0046598	positive regulation of viral entry into host cell
0.33	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.62	GO:0008270	zinc ion binding
0.46	GO:0016874	ligase activity
0.39	GO:0042802	identical protein binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0008168	methyltransferase activity
0.34	GO:0003723	RNA binding
0.33	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0016235	aggresome
0.42	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.46	EC:6	GO:0016874
0.37	KEGG:R03876	GO:0004842

sp|Q86UV7|TRI73_HUMAN
Tripartite motif-containing protein 73
Search

0.86	Tripartite motif-containing protein 73

0.55	GO:0070201	regulation of establishment of protein localization
0.37	GO:0016567	protein ubiquitination
0.35	GO:0039023	pronephric duct morphogenesis
0.35	GO:0070121	Kupffer's vesicle development
0.35	GO:0032402	melanosome transport
0.35	GO:0007369	gastrulation
0.34	GO:0032259	methylation
0.33	GO:0051260	protein homooligomerization
0.33	GO:0046598	positive regulation of viral entry into host cell
0.33	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.62	GO:0008270	zinc ion binding
0.46	GO:0016874	ligase activity
0.39	GO:0042802	identical protein binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0008168	methyltransferase activity
0.34	GO:0003723	RNA binding
0.33	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0016235	aggresome
0.42	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.46	EC:6	GO:0016874
0.37	KEGG:R03876	GO:0004842

sp|Q86UW1|OSTA_HUMAN
Organic solute transporter subunit alpha
Search

SLC51A

0.97	Organic solute transporter subunit alpha

0.65	GO:0032782	bile acid secretion
0.64	GO:0015721	bile acid and bile salt transport
0.44	GO:0055085	transmembrane transport

0.63	GO:0015125	bile acid transmembrane transporter activity
0.56	GO:0042803	protein homodimerization activity
0.55	GO:0046982	protein heterodimerization activity

0.59	GO:0016323	basolateral plasma membrane
0.54	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q86UW2|OSTB_HUMAN
Organic solute transporter subunit beta
Search

SLC51B

0.97	Organic solute transporter subunit beta

0.86	GO:0015721	bile acid and bile salt transport
0.81	GO:0032782	bile acid secretion
0.79	GO:0060050	positive regulation of protein glycosylation
0.78	GO:0070863	positive regulation of protein exit from endoplasmic reticulum
0.77	GO:0090314	positive regulation of protein targeting to membrane
0.69	GO:0031647	regulation of protein stability
0.50	GO:0055085	transmembrane transport

0.77	GO:0015125	bile acid transmembrane transporter activity
0.74	GO:0046982	protein heterodimerization activity

0.73	GO:0016323	basolateral plasma membrane
0.53	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|Q86UW5|Q86UW5_HUMAN
Putative uncharacterized protein HSPC047
Search

0.44	Ras GTPase-activating protein 4

sp|Q86UW6|N4BP2_HUMAN
NEDD4-binding protein 2
Search

N4BP2

0.93	NEDD4-binding protein 2

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0016310	phosphorylation

0.86	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
0.65	GO:0004519	endonuclease activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032553	ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005515	protein binding

0.67	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.86	EC:2.7.1.78	GO:0046404
0.86	KEGG:R03840	GO:0046404

sp|Q86UW7|CAPS2_HUMAN
Calcium-dependent secretion activator 2
Search

CADPS2

0.85	Calcium dependent secretion activator

0.85	GO:1990504	dense core granule exocytosis
0.83	GO:0016079	synaptic vesicle exocytosis
0.58	GO:0045921	positive regulation of exocytosis
0.56	GO:0140029	exocytic process
0.54	GO:0009267	cellular response to starvation
0.51	GO:0043623	cellular protein complex assembly
0.38	GO:0050432	catecholamine secretion
0.37	GO:0016050	vesicle organization
0.36	GO:0015031	protein transport

0.38	GO:0008289	lipid binding
0.36	GO:0019901	protein kinase binding
0.34	GO:0046872	metal ion binding

0.78	GO:0098793	presynapse
0.55	GO:0045211	postsynaptic membrane
0.52	GO:0031410	cytoplasmic vesicle
0.50	GO:0005654	nucleoplasm
0.38	GO:0012506	vesicle membrane
0.38	GO:0030054	cell junction
0.34	GO:0012505	endomembrane system

sp|Q86UW8|HPLN4_HUMAN
Hyaluronan and proteoglycan link protein 4
Search

HAPLN4

0.94	Hyaluronan and proteoglycan link protein 4

0.71	GO:0007155	cell adhesion
0.50	GO:0001501	skeletal system development
0.49	GO:0007417	central nervous system development
0.37	GO:0008065	establishment of blood-nerve barrier
0.36	GO:0085029	extracellular matrix assembly
0.34	GO:0002040	sprouting angiogenesis

0.83	GO:0005540	hyaluronic acid binding
0.51	GO:0005201	extracellular matrix structural constituent
0.34	GO:0042802	identical protein binding

0.50	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q86UW9|DTX2_HUMAN
Probable E3 ubiquitin-protein ligase DTX2
Search

DTX2

0.96	Deltex E3 ubiquitin ligase 2

0.56	GO:0007219	Notch signaling pathway
0.37	GO:0016567	protein ubiquitination
0.34	GO:0045581	negative regulation of T cell differentiation
0.34	GO:1990823	response to leukemia inhibitory factor
0.34	GO:0008593	regulation of Notch signaling pathway
0.34	GO:0045665	negative regulation of neuron differentiation
0.34	GO:0010001	glial cell differentiation
0.34	GO:0071345	cellular response to cytokine stimulus

0.61	GO:0008270	zinc ion binding
0.49	GO:0016874	ligase activity
0.36	GO:0005515	protein binding
0.34	GO:0016740	transferase activity

0.54	GO:0031965	nuclear membrane
0.49	GO:0005654	nucleoplasm
0.36	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm

0.49

GO:0016874

sp|Q86UX2|ITIH5_HUMAN
Inter-alpha-trypsin inhibitor heavy chain H5
Search

ITIH5

0.96	Inter-alpha-trypsin inhibitor heavy chain family member 5

0.84	GO:0030212	hyaluronan metabolic process
0.75	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0006953	acute-phase response
0.34	GO:0034097	response to cytokine

0.77

GO:0004867

serine-type endopeptidase inhibitor activity

0.38	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q86UX6|ST32C_HUMAN
Serine/threonine-protein kinase 32C
Search

STK32C

0.97	Serine/threonine-protein kinase 32C

0.62	GO:0006468	protein phosphorylation
0.48	GO:0018209	peptidyl-serine modification
0.41	GO:0035556	intracellular signal transduction

0.62	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding

0.35

GO:0005622

intracellular

sp|Q86UX7|URP2_HUMAN
Fermitin family homolog 3
Search

FERMT3

0.94	Fermitin family like protein 3

0.80	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0033628	regulation of cell adhesion mediated by integrin
0.61	GO:0033622	integrin activation
0.58	GO:0034446	substrate adhesion-dependent cell spreading
0.57	GO:0070527	platelet aggregation
0.57	GO:0007159	leukocyte cell-cell adhesion
0.53	GO:0030335	positive regulation of cell migration
0.51	GO:0022407	regulation of cell-cell adhesion
0.48	GO:0051546	keratinocyte migration
0.48	GO:0051886	negative regulation of timing of anagen

0.55	GO:0005178	integrin binding
0.41	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.57	GO:0002102	podosome
0.48	GO:0031941	filamentous actin
0.48	GO:0005925	focal adhesion
0.42	GO:0005829	cytosol
0.39	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0097517	contractile actin filament bundle
0.39	GO:0042641	actomyosin
0.39	GO:0043233	organelle lumen
0.38	GO:0042995	cell projection
0.38	GO:0044428	nuclear part

sp|Q86UY5|FA83A_HUMAN
Protein FAM83A
Search

sp|Q86UY6|NAA40_HUMAN
N-alpha-acetyltransferase 40
Search

NAA40

0.94	N-alpha-acetyltransferase 40, NatD catalytic subunit

0.56	GO:0043968	histone H2A acetylation
0.55	GO:0043967	histone H4 acetylation
0.53	GO:0006474	N-terminal protein amino acid acetylation
0.45	GO:0006629	lipid metabolic process
0.34	GO:0016579	protein deubiquitination
0.33	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0022900	electron transport chain
0.32	GO:0043043	peptide biosynthetic process
0.31	GO:0009059	macromolecule biosynthetic process

0.66	GO:0008080	N-acetyltransferase activity
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0005515	protein binding
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0003735	structural constituent of ribosome

0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.66

EC:2.3.1

GO:0008080

sp|Q86UY8|NT5D3_HUMAN
5'-nucleotidase domain-containing protein 3
Search

NT5DC3

0.96	5'-nucleotidase domain-containing protein 3

0.44

GO:0016311

dephosphorylation

0.52	GO:0046872	metal ion binding
0.48	GO:0008253	5'-nucleotidase activity

0.54	GO:0043235	receptor complex
0.35	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion

0.48

EC:3.1.3.5

GO:0008253

sp|Q86UZ6|ZBT46_HUMAN
Zinc finger and BTB domain-containing protein 46
Search

ZBTB46

0.97	Zinc finger and BTB domain-containing protein 46

0.71	GO:2001200	positive regulation of dendritic cell differentiation
0.71	GO:2001199	negative regulation of dendritic cell differentiation
0.70	GO:0045650	negative regulation of macrophage differentiation
0.69	GO:0045656	negative regulation of monocyte differentiation
0.69	GO:0030853	negative regulation of granulocyte differentiation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.36

GO:0005634

nucleus

sp|Q86V15|CASZ1_HUMAN
Zinc finger protein castor homolog 1
Search

CASZ1

0.92	Zinc finger protein castor like protein 1

0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0045664	regulation of neuron differentiation
0.37	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.30	GO:0043167	ion binding

0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol

sp|Q86V20|FA35A_HUMAN
Protein FAM35A
Search

0.30

GO:0044425

membrane part

sp|Q86V21|AACS_HUMAN
Acetoacetyl-CoA synthetase
Search

AACS

0.66	Acetoacetyl-CoA synthetase

0.62	GO:0006629	lipid metabolic process
0.41	GO:0034201	response to oleic acid
0.41	GO:0071394	cellular response to testosterone stimulus
0.41	GO:0071397	cellular response to cholesterol
0.41	GO:0050872	white fat cell differentiation
0.40	GO:0060612	adipose tissue development
0.40	GO:0032024	positive regulation of insulin secretion
0.40	GO:0071333	cellular response to glucose stimulus
0.40	GO:0045471	response to ethanol
0.40	GO:0001889	liver development

0.82	GO:0030729	acetoacetate-CoA ligase activity
0.41	GO:0047760	butyrate-CoA ligase activity
0.36	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.82	EC:6.2.1.16	GO:0030729
0.82	KEGG:R01357	GO:0030729

sp|Q86V24|ADR2_HUMAN
Adiponectin receptor protein 2
Search

ADIPOR2

0.97	Adiponectin receptor protein 2

0.61	GO:0033211	adiponectin-activated signaling pathway
0.58	GO:0061042	vascular wound healing
0.53	GO:0042593	glucose homeostasis
0.41	GO:0046326	positive regulation of glucose import
0.40	GO:0007565	female pregnancy
0.40	GO:0030308	negative regulation of cell growth
0.40	GO:0007584	response to nutrient
0.39	GO:0007507	heart development
0.37	GO:0019395	fatty acid oxidation
0.36	GO:0019216	regulation of lipid metabolic process

0.60	GO:0097003	adipokinetic hormone receptor activity
0.60	GO:0055100	adiponectin binding
0.50	GO:0046982	protein heterodimerization activity
0.50	GO:0042802	identical protein binding
0.34	GO:0019901	protein kinase binding
0.33	GO:0046872	metal ion binding

0.47	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q86V25|VASH2_HUMAN
Vasohibin-2
Search

VASH2

0.96	Testicular tissue protein Li 222

0.82	GO:0045765	regulation of angiogenesis
0.65	GO:0001936	regulation of endothelial cell proliferation
0.62	GO:0060716	labyrinthine layer blood vessel development
0.58	GO:0000768	syncytium formation by plasma membrane fusion
0.57	GO:0045026	plasma membrane fusion
0.56	GO:1904018	positive regulation of vasculature development
0.56	GO:0050679	positive regulation of epithelial cell proliferation
0.53	GO:0050680	negative regulation of epithelial cell proliferation
0.53	GO:2000181	negative regulation of blood vessel morphogenesis
0.52	GO:1901491	negative regulation of lymphangiogenesis

0.33

GO:0005515

protein binding

0.49	GO:0005737	cytoplasm
0.47	GO:0045177	apical part of cell
0.44	GO:0005615	extracellular space
0.43	GO:0012505	endomembrane system
0.39	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q86V35|CABP7_HUMAN
Calcium-binding protein 7
Search

CABP7

0.97	Calcium binding protein 7

0.70

GO:0005509

calcium ion binding

0.64	GO:0032588	trans-Golgi network membrane
0.42	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005689	U12-type spliceosomal complex
0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q86V40|TIKI1_HUMAN
Metalloprotease TIKI1
Search

0.96	TraB domain containing 2A

0.80	GO:0030178	negative regulation of Wnt signaling pathway
0.68	GO:1904808	positive regulation of protein oxidation
0.63	GO:0032461	positive regulation of protein oligomerization
0.59	GO:0006508	proteolysis

0.84	GO:0017147	Wnt-protein binding
0.68	GO:0004222	metalloendopeptidase activity

0.74	GO:0031301	integral component of organelle membrane
0.65	GO:0005887	integral component of plasma membrane
0.40	GO:0070062	extracellular exosome

0.68

GO:0004222

sp|Q86V42|F124A_HUMAN
Protein FAM124A
Search

0.39	GO:0006182	cGMP biosynthetic process
0.36	GO:0035556	intracellular signal transduction

0.44	GO:0005515	protein binding
0.39	GO:0004383	guanylate cyclase activity
0.36	GO:0020037	heme binding
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0036094	small molecule binding

0.60	GO:0005654	nucleoplasm
0.53	GO:0005739	mitochondrion
0.45	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:4.6.1.2

GO:0004383

sp|Q86V48|LUZP1_HUMAN
Leucine zipper protein 1
Search

LUZP1

0.97	Leucine zipper protein 1

0.88	GO:0021503	neural fold bending
0.85	GO:0003281	ventricular septum development
0.85	GO:0060840	artery development

0.61	GO:0005634	nucleus
0.46	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q86V59|PNML1_HUMAN
PNMA-like protein 1
Search

PNMA8A

0.97	Paraneoplastic Ma antigen family member 8A

0.53	GO:0002437	inflammatory response to antigenic stimulus
0.42	GO:0043065	positive regulation of apoptotic process

0.38

GO:0005515

protein binding

0.70	GO:0005730	nucleolus
0.46	GO:0005737	cytoplasm

sp|Q86V71|ZN429_HUMAN
Zinc finger protein 429
Search

0.72	Zinc finger protein 85

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.38	GO:0097659	nucleic acid-templated transcription
0.37	GO:0010467	gene expression
0.37	GO:0034645	cellular macromolecule biosynthetic process

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|Q86V81|THOC4_HUMAN
THO complex subunit 4
Search

ALYREF

0.91	RNA and export factor binding protein 2

0.41	GO:0051028	mRNA transport
0.40	GO:0008380	RNA splicing
0.39	GO:0006397	mRNA processing
0.37	GO:0046784	viral mRNA export from host cell nucleus
0.37	GO:0050790	regulation of catalytic activity
0.37	GO:0001649	osteoblast differentiation
0.37	GO:0031297	replication fork processing
0.36	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.36	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.36	GO:0000018	regulation of DNA recombination

0.59	GO:0003723	RNA binding
0.40	GO:0005094	Rho GDP-dissociation inhibitor activity
0.37	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity
0.36	GO:0003697	single-stranded DNA binding
0.35	GO:0070403	NAD+ binding
0.33	GO:0005515	protein binding
0.32	GO:0016853	isomerase activity

0.50	GO:0016607	nuclear speck
0.39	GO:0005681	spliceosomal complex
0.37	GO:0035145	exon-exon junction complex
0.37	GO:0000346	transcription export complex
0.36	GO:0000784	nuclear chromosome, telomeric region
0.36	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.34	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

0.37

EC:2.7.7.14

GO:0004306

sp|Q86V85|GP180_HUMAN
Integral membrane protein GPR180
Search

GPR180

0.88	G protein-coupled receptor 180

0.82	GO:0019236	response to pheromone
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.39	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q86V86|PIM3_HUMAN
Serine/threonine-protein kinase pim-3
Search

PIM3

0.93	Proto-oncogene serine/threonine-protein kinase pim-1

0.77	GO:0043066	negative regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.51	GO:1905062	positive regulation of cardioblast proliferation
0.51	GO:0007346	regulation of mitotic cell cycle
0.50	GO:0070561	vitamin D receptor signaling pathway
0.50	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.49	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.47	GO:0043433	negative regulation of DNA binding transcription factor activity
0.46	GO:0008283	cell proliferation
0.41	GO:0006915	apoptotic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0043024	ribosomal small subunit binding
0.44	GO:0008134	transcription factor binding
0.44	GO:0030145	manganese ion binding
0.33	GO:0005509	calcium ion binding

0.49	GO:0005829	cytosol
0.44	GO:0005730	nucleolus
0.33	GO:0005886	plasma membrane
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

sp|Q86V87|F16B2_HUMAN
Protein FAM160B2
Search

0.93	Retinoic acid induced 16

sp|Q86V88|MGDP1_HUMAN
Magnesium-dependent phosphatase 1
Search

MDP1

0.43	Magnesium-dependent phosphatase

0.68	GO:0016311	dephosphorylation
0.41	GO:0030389	fructosamine metabolic process
0.39	GO:0007034	vacuolar transport
0.35	GO:0006464	cellular protein modification process
0.32	GO:0055114	oxidation-reduction process

0.69	GO:0016791	phosphatase activity
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0046872	metal ion binding
0.32	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.32	GO:0003676	nucleic acid binding

0.38

GO:0070062

extracellular exosome

0.69

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q86V97|KBTB6_HUMAN
Kelch repeat and BTB domain-containing protein 6
Search

KBTBD7

0.97	LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 6

0.73	GO:0016567	protein ubiquitination
0.48	GO:0043687	post-translational protein modification
0.42	GO:0000165	MAPK cascade
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.73	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0005515	protein binding
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.44	GO:0005829	cytosol
0.32	GO:0005634	nucleus

0.73

GO:0004842

sp|Q86VB7|C163A_HUMAN
Scavenger receptor cysteine-rich type 1 protein M130
Search

0.10	Scavenger receptor cysteine-rich type 1 protein M130

0.72	GO:0006898	receptor-mediated endocytosis
0.30	GO:0006950	response to stress

0.81	GO:0005044	scavenger receptor activity
0.30	GO:0005488	binding

0.47	GO:0009897	external side of plasma membrane
0.30	GO:0044422	organelle part
0.30	GO:0005737	cytoplasm
0.30	GO:0005576	extracellular region
0.30	GO:0098805	whole membrane
0.30	GO:0031982	vesicle
0.30	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane
0.30	GO:0043229	intracellular organelle

sp|Q86VD1|MORC1_HUMAN
MORC family CW-type zinc finger protein 1
Search

MORC1

0.90	MORC family CW-type zinc finger protein 1

0.60	GO:0044026	DNA hypermethylation
0.59	GO:2000143	negative regulation of DNA-templated transcription, initiation
0.58	GO:0043046	DNA methylation involved in gamete generation
0.58	GO:0010529	negative regulation of transposition
0.54	GO:0007283	spermatogenesis
0.53	GO:0040029	regulation of gene expression, epigenetic
0.37	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development
0.33	GO:0006631	fatty acid metabolic process
0.33	GO:0055114	oxidation-reduction process

0.62	GO:0008270	zinc ion binding
0.33	GO:0016491	oxidoreductase activity

0.49	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0016491

sp|Q86VD7|S2542_HUMAN
Mitochondrial coenzyme A transporter SLC25A42
Search

SLC25A42

0.95	Mitochondrial coenzyme A transporter SLC25A42

0.60	GO:0080121	AMP transport
0.59	GO:0071106	adenosine 3',5'-bisphosphate transmembrane transport
0.59	GO:0015880	coenzyme A transport
0.57	GO:0015866	ADP transport
0.55	GO:0015867	ATP transport
0.49	GO:0098656	anion transmembrane transport
0.48	GO:0006839	mitochondrial transport
0.35	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0045089	positive regulation of innate immune response
0.34	GO:0007006	mitochondrial membrane organization

0.60	GO:0080122	AMP transmembrane transporter activity
0.59	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity
0.59	GO:0043262	adenosine-diphosphatase activity
0.57	GO:0015217	ADP transmembrane transporter activity
0.55	GO:0005347	ATP transmembrane transporter activity
0.54	GO:0051185	coenzyme transmembrane transporter activity
0.36	GO:0015297	antiporter activity

0.57	GO:0031966	mitochondrial membrane
0.57	GO:0019866	organelle inner membrane
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q86VD9|PIGZ_HUMAN
GPI mannosyltransferase 4
Search

PIGZ

0.53	Mannosyltransferase

0.61	GO:0006506	GPI anchor biosynthetic process
0.61	GO:0097502	mannosylation
0.33	GO:0006276	plasmid maintenance

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0070403	NAD+ binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

sp|Q86VE0|MYPOP_HUMAN
Myb-related transcription factor, partner of profilin
Search

MYPOP

0.97	Myb-related transcription factor, partner of profilin

0.78	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0006351	transcription, DNA-templated

0.84	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.80	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.75	GO:0042803	protein homodimerization activity

0.61

GO:0005634

nucleus

sp|Q86VE3|SATL1_HUMAN
Spermidine/spermine N(1)-acetyltransferase-like protein 1
Search

SATL1

0.88	Spermidine/spermine N1-acetyl transferase like 1

0.55	GO:0032918	spermidine acetylation
0.55	GO:0046208	spermine catabolic process
0.51	GO:0001525	angiogenesis
0.47	GO:0042127	regulation of cell proliferation
0.42	GO:0009447	putrescine catabolic process
0.37	GO:0032919	spermine acetylation
0.34	GO:0006596	polyamine biosynthetic process

0.80	GO:0004145	diamine N-acetyltransferase activity
0.56	GO:0019809	spermidine binding
0.48	GO:0042802	identical protein binding

0.45	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.3.1.57

GO:0004145

sp|Q86VE9|SERC5_HUMAN
Serine incorporator 5
Search

SERINC5

0.97	Serine incorporator 5

0.80	GO:0006658	phosphatidylserine metabolic process
0.80	GO:0042552	myelination
0.75	GO:0006665	sphingolipid metabolic process
0.57	GO:0009597	detection of virus
0.51	GO:0045087	innate immune response
0.51	GO:0051607	defense response to virus
0.50	GO:0015825	L-serine transport
0.40	GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.40	GO:1904222	positive regulation of serine C-palmitoyltransferase activity
0.37	GO:0008654	phospholipid biosynthetic process

0.51	GO:0015194	L-serine transmembrane transporter activity
0.34	GO:0030674	protein binding, bridging
0.34	GO:0051537	2 iron, 2 sulfur cluster binding

0.53	GO:0043209	myelin sheath
0.48	GO:0005794	Golgi apparatus
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q86VF2|IGFN1_HUMAN
Immunoglobulin-like and fibronectin type III domain-containing protein 1
Search

IGFN1

0.82	Immunoglobulin-like and fibronectin type III domain-containing protein 1

0.56	GO:0006468	protein phosphorylation
0.40	GO:0071688	striated muscle myosin thick filament assembly
0.40	GO:0098609	cell-cell adhesion
0.39	GO:0045214	sarcomere organization
0.39	GO:0006941	striated muscle contraction
0.38	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.38	GO:0038084	vascular endothelial growth factor signaling pathway
0.37	GO:0007015	actin filament organization
0.37	GO:0018212	peptidyl-tyrosine modification
0.36	GO:1905563	negative regulation of vascular endothelial cell proliferation

0.57	GO:0004672	protein kinase activity
0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005515	protein binding
0.40	GO:0097493	structural molecule activity conferring elasticity
0.39	GO:0008307	structural constituent of muscle
0.37	GO:0044877	macromolecular complex binding
0.36	GO:0004888	transmembrane signaling receptor activity

0.56	GO:0030018	Z disc
0.46	GO:0005634	nucleus
0.41	GO:0030057	desmosome
0.40	GO:0005859	muscle myosin complex
0.39	GO:0031430	M band
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0043235	receptor complex
0.34	GO:0030673	axolemma
0.33	GO:0005768	endosome
0.33	GO:0005576	extracellular region

sp|Q86VF5|MOGT3_HUMAN
2-acylglycerol O-acyltransferase 3
Search

MOGAT3

0.88	Monoacylglycerol O-acyltransferase 3

0.46	GO:0046463	acylglycerol biosynthetic process
0.45	GO:0046339	diacylglycerol metabolic process
0.43	GO:0006641	triglyceride metabolic process
0.39	GO:0050892	intestinal absorption
0.39	GO:0006071	glycerol metabolic process
0.36	GO:0071400	cellular response to oleic acid
0.36	GO:0060613	fat pad development
0.36	GO:0035356	cellular triglyceride homeostasis
0.36	GO:0034383	low-density lipoprotein particle clearance
0.36	GO:1901568	fatty acid derivative metabolic process

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.35	GO:0042803	protein homodimerization activity

0.42	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.37	GO:0005811	lipid droplet
0.35	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.64

EC:2.3.1

GO:0016747

sp|Q86VF7|NRAP_HUMAN
Nebulin-related-anchoring protein
Search

NRAP

0.66	nebulin-related-anchoring protein isoform X1

0.34

GO:0030036

actin cytoskeleton organization

0.73	GO:0003779	actin binding
0.57	GO:0051371	muscle alpha-actinin binding
0.57	GO:0017166	vinculin binding
0.52	GO:0046872	metal ion binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032555	purine ribonucleotide binding

0.58	GO:0005916	fascia adherens
0.57	GO:0005927	muscle tendon junction
0.53	GO:0030016	myofibril
0.34	GO:0044449	contractile fiber part

sp|Q86VG3|CK074_HUMAN
Uncharacterized protein C11orf74
Search

sp|Q86VH2|KIF27_HUMAN
Kinesin-like protein KIF27
Search

KIF27

0.93	Kinesin family member 7

0.74	GO:0007018	microtubule-based movement
0.33	GO:0045880	positive regulation of smoothened signaling pathway
0.33	GO:0045879	negative regulation of smoothened signaling pathway
0.33	GO:0060976	coronary vasculature development
0.33	GO:0035904	aorta development
0.33	GO:0003279	cardiac septum development

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042623	ATPase activity, coupled
0.33	GO:0042802	identical protein binding

0.58	GO:0005871	kinesin complex
0.44	GO:0005929	cilium
0.33	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005815	microtubule organizing center

sp|Q86VH4|LRRT4_HUMAN
Leucine-rich repeat transmembrane neuronal protein 4
Search

LRRTM4

0.96	Leucine-rich repeat transmembrane neuronal protein 4

0.47	GO:0046426	negative regulation of JAK-STAT cascade
0.45	GO:0006469	negative regulation of protein kinase activity
0.45	GO:0019221	cytokine-mediated signaling pathway
0.39	GO:0050808	synapse organization
0.38	GO:1901629	regulation of presynaptic membrane organization
0.37	GO:0043113	receptor clustering
0.37	GO:0051965	positive regulation of synapse assembly
0.35	GO:0061024	membrane organization

0.46	GO:0004860	protein kinase inhibitor activity
0.37	GO:0043395	heparan sulfate proteoglycan binding

0.37	GO:0045211	postsynaptic membrane
0.37	GO:0032281	AMPA glutamate receptor complex
0.37	GO:0030054	cell junction
0.36	GO:0005737	cytoplasm

sp|Q86VH5|LRRT3_HUMAN
Leucine-rich repeat transmembrane neuronal protein 3
Search

LRRTM3

0.97	Leucine-rich repeat transmembrane neuronal protein 3

0.58	GO:1902004	positive regulation of amyloid-beta formation
0.52	GO:0051965	positive regulation of synapse assembly
0.50	GO:0046426	negative regulation of JAK-STAT cascade
0.48	GO:0006469	negative regulation of protein kinase activity
0.47	GO:0019221	cytokine-mediated signaling pathway
0.36	GO:1901629	regulation of presynaptic membrane organization
0.36	GO:0097113	AMPA glutamate receptor clustering

0.49	GO:0004860	protein kinase inhibitor activity
0.36	GO:0043395	heparan sulfate proteoglycan binding

0.40	GO:0045211	postsynaptic membrane
0.39	GO:0030054	cell junction
0.37	GO:0005737	cytoplasm
0.36	GO:0032281	AMPA glutamate receptor complex

sp|Q86VI1|EX3L1_HUMAN
Exocyst complex component 3-like protein
Search

EXOC3L1

0.92	Exocyst complex component 3 like 1

0.77	GO:0006887	exocytosis
0.69	GO:0030072	peptide hormone secretion
0.55	GO:0051601	exocyst localization
0.32	GO:0006508	proteolysis

0.52	GO:0000149	SNARE binding
0.32	GO:0004252	serine-type endopeptidase activity

0.79	GO:0000145	exocyst
0.65	GO:0030141	secretory granule
0.41	GO:0030133	transport vesicle

0.32

GO:0004252

sp|Q86VI3|IQGA3_HUMAN
Ras GTPase-activating-like protein IQGAP3
Search

IQGAP3

0.91	IQ motif containing GTPase activating protein 3

0.75	GO:0043087	regulation of GTPase activity
0.65	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.63	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.62	GO:0070371	ERK1 and ERK2 cascade
0.60	GO:0071310	cellular response to organic substance
0.59	GO:0000082	G1/S transition of mitotic cell cycle
0.58	GO:0007265	Ras protein signal transduction
0.58	GO:0008361	regulation of cell size
0.57	GO:0043405	regulation of MAP kinase activity
0.57	GO:0043410	positive regulation of MAPK cascade

0.65	GO:0070856	myosin VI light chain binding
0.64	GO:0005516	calmodulin binding
0.60	GO:0017048	Rho GTPase binding
0.56	GO:0044548	S100 protein binding
0.56	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.55	GO:0043539	protein serine/threonine kinase activator activity
0.54	GO:0019903	protein phosphatase binding
0.53	GO:0045296	cadherin binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0019904	protein domain specific binding

0.66	GO:0016328	lateral plasma membrane
0.60	GO:0005911	cell-cell junction
0.54	GO:0001726	ruffle
0.54	GO:0030496	midbody
0.52	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.52	GO:0036464	cytoplasmic ribonucleoprotein granule
0.49	GO:0005874	microtubule
0.49	GO:0043005	neuron projection
0.44	GO:0005634	nucleus
0.44	GO:0030427	site of polarized growth

sp|Q86VI4|LAP4B_HUMAN
Lysosomal-associated transmembrane protein 4B
Search

LAPTM4B

0.96	Lysosomal associated protein transmembrane 4 beta

0.61	GO:1905671	regulation of lysosome organization
0.61	GO:1905166	negative regulation of lysosomal protein catabolic process
0.61	GO:0097213	regulation of lysosomal membrane permeability
0.60	GO:0032911	negative regulation of transforming growth factor beta1 production
0.56	GO:0007032	endosome organization
0.55	GO:0032509	endosome transport via multivesicular body sorting pathway

0.59	GO:0097001	ceramide binding
0.55	GO:1902936	phosphatidylinositol bisphosphate binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0019900	kinase binding

0.60	GO:0097487	multivesicular body, internal vesicle
0.59	GO:0032585	multivesicular body membrane
0.55	GO:0005765	lysosomal membrane
0.54	GO:0005769	early endosome
0.48	GO:0042995	cell projection
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q86VK4|ZN410_HUMAN
Zinc finger protein 410
Search

ZNF410

0.97	Zinc finger protein 410

0.35	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0006744	ubiquinone biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.51	GO:0003676	nucleic acid binding
0.34	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.34	GO:0046872	metal ion binding
0.34	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.34	GO:0071949	FAD binding
0.33	GO:0005515	protein binding

0.35	GO:0005634	nucleus
0.34	GO:0031314	extrinsic component of mitochondrial inner membrane
0.34	GO:0005794	Golgi apparatus
0.33	GO:0042995	cell projection
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.14.14

GO:0016712

sp|Q86VL8|S47A2_HUMAN
Multidrug and toxin extrusion protein 2
Search

SLC47A2

0.74	Multidrug and toxin extrusion protein 2

0.72	GO:0006855	drug transmembrane transport
0.41	GO:0046618	drug export
0.34	GO:0055114	oxidation-reduction process

0.72	GO:0015238	drug transmembrane transporter activity
0.72	GO:0015297	antiporter activity
0.37	GO:0015078	hydrogen ion transmembrane transporter activity
0.36	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0001883	purine nucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032549	ribonucleoside binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032555	purine ribonucleotide binding

0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.36

EC:1.2.1

GO:0016620

sp|Q86VM9|ZCH18_HUMAN
Zinc finger CCCH domain-containing protein 18
Search

ZC3H18

0.93	Zinc finger CCCH domain-containing protein 18

0.34	GO:0006954	inflammatory response
0.34	GO:0010469	regulation of receptor activity

0.52	GO:0046872	metal ion binding
0.35	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0030545	receptor regulator activity

0.54	GO:0016607	nuclear speck
0.36	GO:0043234	protein complex
0.33	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q86VN1|VPS36_HUMAN
Vacuolar protein-sorting-associated protein 36
Search

VPS36

0.91	Vacuolar protein-sorting-associated protein 36

0.78	GO:0032509	endosome transport via multivesicular body sorting pathway
0.48	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.48	GO:0045324	late endosome to vacuole transport
0.47	GO:0072666	establishment of protein localization to vacuole
0.43	GO:0006886	intracellular protein transport
0.36	GO:0036258	multivesicular body assembly
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.79	GO:0032266	phosphatidylinositol-3-phosphate binding
0.78	GO:0043130	ubiquitin binding
0.55	GO:0008022	protein C-terminus binding
0.35	GO:0003730	mRNA 3'-UTR binding

0.79	GO:0000814	ESCRT II complex
0.57	GO:0031902	late endosome membrane
0.53	GO:0005764	lysosome
0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus

sp|Q86VP1|TAXB1_HUMAN
Tax1-binding protein 1
Search

TAX1BP1

0.93	Muscle-derived protein 62

0.83	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0006915	apoptotic process
0.46	GO:0043066	negative regulation of apoptotic process
0.43	GO:0032480	negative regulation of type I interferon production
0.43	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
0.38	GO:0010976	positive regulation of neuron projection development
0.33	GO:0006811	ion transport

0.76	GO:0019900	kinase binding
0.41	GO:0046872	metal ion binding
0.39	GO:0043130	ubiquitin binding

0.44	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|Q86VP3|PACS2_HUMAN
Phosphofurin acidic cluster sorting protein 2
Search

PACS2

0.94	Phosphofurin acidic cluster sorting protein 2

0.82	GO:0034497	protein localization to phagophore assembly site
0.78	GO:0072659	protein localization to plasma membrane
0.43	GO:0006915	apoptotic process
0.37	GO:0016032	viral process

0.66

GO:0044325

ion channel binding

0.67	GO:0005783	endoplasmic reticulum
0.58	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q86VP6|CAND1_HUMAN
Cullin-associated NEDD8-dissociated protein 1
Search

CAND1

0.79	Cullin-associated and neddylation-dissociated protein 1

0.86	GO:0010265	SCF complex assembly
0.70	GO:0016567	protein ubiquitination
0.64	GO:0043086	negative regulation of catalytic activity
0.64	GO:0030154	cell differentiation
0.58	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.47	GO:0043312	neutrophil degranulation
0.45	GO:0043687	post-translational protein modification
0.44	GO:0006879	cellular iron ion homeostasis
0.40	GO:0010467	gene expression
0.39	GO:0009059	macromolecule biosynthetic process

0.56	GO:0017025	TBP-class protein binding
0.40	GO:0003735	structural constituent of ribosome

0.71	GO:0031461	cullin-RING ubiquitin ligase complex
0.65	GO:0005794	Golgi apparatus
0.63	GO:0005654	nucleoplasm
0.62	GO:0005829	cytosol
0.51	GO:0070062	extracellular exosome
0.48	GO:1904813	ficolin-1-rich granule lumen
0.47	GO:0034774	secretory granule lumen
0.39	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|Q86VQ0|LCA5_HUMAN
Lebercilin
Search

LCA5

0.95	Leber congenital amaurosis 5

0.44	GO:0045494	photoreceptor cell maintenance
0.43	GO:0042073	intraciliary transport

0.75	GO:0032403	protein complex binding
0.35	GO:0031492	nucleosomal DNA binding

0.76	GO:0005929	cilium
0.45	GO:0005815	microtubule organizing center
0.42	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.34	GO:0000785	chromatin
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q86VQ1|GLCI1_HUMAN
Glucocorticoid-induced transcript 1 protein
Search

GLCCI1

0.96	Glucocorticoid-induced transcript 1 protein isoform B

0.55

GO:0005515

protein binding

0.49

GO:0005737

cytoplasm

sp|Q86VQ3|TXND2_HUMAN
Thioredoxin domain-containing protein 2
Search

TXNDC2

0.94	LOW QUALITY PROTEIN: thioredoxin domain-containing protein 2

0.76	GO:0006662	glycerol ether metabolic process
0.69	GO:0045454	cell redox homeostasis
0.55	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0034599	cellular response to oxidative stress
0.46	GO:0007283	spermatogenesis
0.44	GO:0030154	cell differentiation
0.43	GO:0007275	multicellular organism development
0.42	GO:0046826	negative regulation of protein export from nucleus
0.42	GO:0033158	regulation of protein import into nucleus, translocation

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.61	GO:0004791	thioredoxin-disulfide reductase activity
0.55	GO:0047134	protein-disulfide reductase activity
0.52	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.40	GO:0015037	peptide disulfide oxidoreductase activity
0.39	GO:0003756	protein disulfide isomerase activity
0.35	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.42	GO:0005737	cytoplasm
0.40	GO:0036126	sperm flagellum
0.37	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0005634	nucleus
0.35	GO:0099513	polymeric cytoskeletal fiber
0.35	GO:0005576	extracellular region
0.35	GO:0043025	neuronal cell body
0.35	GO:0097447	dendritic tree
0.35	GO:0030424	axon
0.34	GO:0031982	vesicle

0.61	EC:1.8.1.9	GO:0004791
0.61	KEGG:R02016	GO:0004791

sp|Q86VQ6|TRXR3_HUMAN
Thioredoxin reductase 3
Search

TXNRD3

0.91	Thioredoxin reductase 1, cytoplasmic

0.67	GO:0098869	cellular oxidant detoxification
0.67	GO:0045454	cell redox homeostasis
0.59	GO:0022900	electron transport chain
0.47	GO:0001707	mesoderm formation
0.46	GO:0008283	cell proliferation
0.45	GO:0000305	response to oxygen radical
0.37	GO:0006749	glutathione metabolic process
0.37	GO:0007283	spermatogenesis
0.36	GO:0030154	cell differentiation
0.36	GO:0070276	halogen metabolic process

0.77	GO:0004791	thioredoxin-disulfide reductase activity
0.64	GO:0050660	flavin adenine dinucleotide binding
0.60	GO:0015035	protein disulfide oxidoreductase activity
0.60	GO:0009055	electron transfer activity
0.36	GO:0098626	methylseleninic acid reductase activity
0.36	GO:0098625	methylselenol reductase activity
0.36	GO:0098623	selenite reductase activity
0.35	GO:0033797	selenate reductase activity
0.35	GO:0005515	protein binding
0.35	GO:0016174	NAD(P)H oxidase activity

0.53	GO:0005654	nucleoplasm
0.52	GO:0005829	cytosol
0.49	GO:0001650	fibrillar center
0.43	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0043025	neuronal cell body
0.31	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:1.8.1.9	GO:0004791
0.77	KEGG:R02016	GO:0004791

sp|Q86VR2|F134C_HUMAN
Protein FAM134C
Search

RETREG3

0.97	Reticulophagy regulator 3

0.82	GO:0010976	positive regulation of neuron projection development
0.44	GO:0061709	reticulophagy
0.39	GO:0019233	sensory perception of pain
0.39	GO:0043524	negative regulation of neuron apoptotic process

0.36

GO:0005515

protein binding

0.41	GO:0030176	integral component of endoplasmic reticulum membrane
0.38	GO:0005801	cis-Golgi network
0.38	GO:0016604	nuclear body
0.37	GO:0005730	nucleolus

sp|Q86VR7|VS10L_HUMAN
V-set and immunoglobulin domain-containing protein 10-like
Search

VSIG10L

0.97	V-set and immunoglobulin domain containing 10 like

0.36	GO:0022900	electron transport chain
0.33	GO:0019991	septate junction assembly

0.36

GO:0009055

electron transfer activity

0.59	GO:0005654	nucleoplasm
0.33	GO:0005918	septate junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q86VR8|FJX1_HUMAN
Four-jointed box protein 1
Search

FJX1

0.97	Four-jointed box protein 1

0.85	GO:0010842	retina layer formation
0.62	GO:0007267	cell-cell signaling

0.73

GO:0005615

extracellular space

sp|Q86VS3|IQCH_HUMAN
IQ domain-containing protein H
Search

IQCH

0.97	IQ domain-containing protein H

0.47	GO:0043043	peptide biosynthetic process
0.45	GO:0044267	cellular protein metabolic process
0.44	GO:0010467	gene expression
0.43	GO:0009059	macromolecule biosynthetic process

0.50

GO:0003735

structural constituent of ribosome

0.48

GO:0005840

ribosome

sp|Q86VS8|HOOK3_HUMAN
Protein Hook homolog 3
Search

HOOK3

0.94	Hook microtubule tethering protein 3

0.85	GO:0022027	interkinetic nuclear migration
0.85	GO:0051645	Golgi localization
0.84	GO:0045022	early endosome to late endosome transport
0.84	GO:0097150	neuronal stem cell population maintenance
0.83	GO:0034454	microtubule anchoring at centrosome
0.83	GO:0071539	protein localization to centrosome
0.83	GO:0008333	endosome to lysosome transport
0.82	GO:0031122	cytoplasmic microtubule organization
0.81	GO:0007032	endosome organization
0.81	GO:0007040	lysosome organization

0.73	GO:0008017	microtubule binding
0.70	GO:0042802	identical protein binding
0.63	GO:0051959	dynein light intermediate chain binding
0.48	GO:0008318	protein prenyltransferase activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0070695	FHF complex
0.84	GO:0000242	pericentriolar material
0.83	GO:0034451	centriolar satellite
0.83	GO:0030897	HOPS complex
0.78	GO:0005801	cis-Golgi network
0.66	GO:0005829	cytosol
0.44	GO:0005874	microtubule
0.43	GO:0005794	Golgi apparatus

0.48

EC:2.5.1

GO:0008318

sp|Q86VU5|CMTD1_HUMAN
Catechol O-methyltransferase domain-containing protein 1
Search

COMTD1

0.38	Predicted O-methyltransferase YrrM

0.63

GO:0032259

methylation

0.73	GO:0008171	O-methyltransferase activity
0.34	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.34	GO:0005515	protein binding

0.45	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.73

GO:0008171

sp|Q86VV4|RNB3L_HUMAN
Ran-binding protein 3-like
Search

RANBP3L

0.81	Ran-binding protein 3-like

0.69	GO:0046907	intracellular transport
0.51	GO:0046604	positive regulation of mitotic centrosome separation
0.48	GO:0000082	G1/S transition of mitotic cell cycle
0.47	GO:0006606	protein import into nucleus
0.47	GO:0007051	spindle organization
0.47	GO:1901706	mesenchymal cell differentiation involved in bone development
0.46	GO:0043547	positive regulation of GTPase activity
0.45	GO:0006405	RNA export from nucleus
0.45	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0045663	positive regulation of myoblast differentiation

0.47	GO:0008536	Ran GTPase binding
0.46	GO:0005096	GTPase activator activity
0.45	GO:0046332	SMAD binding
0.40	GO:0003951	NAD+ kinase activity
0.33	GO:0003677	DNA binding

0.46	GO:0005813	centrosome
0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.40	EC:2.7.1.23	GO:0003951
0.40	KEGG:R00104	GO:0003951

sp|Q86VV8|RTTN_HUMAN
Rotatin
Search

RTTN

0.97

Rotatin

0.79	GO:0044782	cilium organization
0.59	GO:0007368	determination of left/right symmetry
0.34	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.35	GO:0033897	ribonuclease T2 activity
0.33	GO:0003723	RNA binding

0.83	GO:0036064	ciliary basal body
0.78	GO:0005813	centrosome
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.1.27.1

GO:0033897

sp|Q86VW0|SESD1_HUMAN
SEC14 domain and spectrin repeat-containing protein 1
Search

SESTD1

0.97	LOW QUALITY PROTEIN: SEC14 domain and spectrin repeat-containing protein 1

0.86	GO:1904878	negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
0.54	GO:0048514	blood vessel morphogenesis

0.82	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.82	GO:0010314	phosphatidylinositol-5-phosphate binding
0.82	GO:0070300	phosphatidic acid binding
0.79	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.79	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.77	GO:0070273	phosphatidylinositol-4-phosphate binding
0.77	GO:0032266	phosphatidylinositol-3-phosphate binding
0.44	GO:0031210	phosphatidylcholine binding
0.43	GO:0001786	phosphatidylserine binding
0.42	GO:0005545	1-phosphatidylinositol binding

0.75	GO:0034704	calcium channel complex
0.73	GO:0045111	intermediate filament cytoskeleton

sp|Q86VW1|S22AG_HUMAN
Solute carrier family 22 member 16
Search

SLC22A16

0.97	Epididymis secretory protein Li 18

0.56	GO:1902603	carnitine transmembrane transport
0.55	GO:0015837	amine transport
0.54	GO:0030317	flagellated sperm motility
0.54	GO:0007338	single fertilization
0.53	GO:0046717	acid secretion
0.44	GO:0015711	organic anion transport
0.38	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development
0.34	GO:0009437	carnitine metabolic process

0.56	GO:0015226	carnitine transmembrane transporter activity
0.50	GO:0005275	amine transmembrane transporter activity
0.45	GO:0008514	organic anion transmembrane transporter activity
0.39	GO:0003884	D-amino-acid oxidase activity
0.34	GO:0015491	cation:cation antiporter activity
0.33	GO:0030165	PDZ domain binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.36	GO:0005887	integral component of plasma membrane
0.33	GO:0016324	apical plasma membrane
0.32	GO:0005739	mitochondrion

0.39

EC:1.4.3.3

GO:0003884

sp|Q86VW2|ARHGP_HUMAN
Rho guanine nucleotide exchange factor 25
Search

ARHGEF25

0.96	Guanine nucleotide exchange factor GEFT

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.38	GO:0006468	protein phosphorylation
0.35	GO:1902358	sulfate transmembrane transport
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0043401	steroid hormone mediated signaling pathway
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.31	GO:0010468	regulation of gene expression

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0015116	sulfate transmembrane transporter activity
0.33	GO:0015291	secondary active transmembrane transporter activity
0.32	GO:0003707	steroid hormone receptor activity
0.31	GO:0003677	DNA binding

0.38	GO:0030017	sarcomere
0.35	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q86VX2|COMD7_HUMAN
COMM domain-containing protein 7
Search

COMMD7

0.97	COMM domain-containing protein 7

0.83	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.83	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.70	GO:0045892	negative regulation of transcription, DNA-templated
0.39	GO:0006351	transcription, DNA-templated
0.35	GO:0006260	DNA replication
0.33	GO:0055114	oxidation-reduction process

0.85	GO:0051059	NF-kappaB binding
0.36	GO:0061731	ribonucleoside-diphosphate reductase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0043231	intracellular membrane-bounded organelle
0.46	GO:0031982	vesicle
0.44	GO:0043230	extracellular organelle
0.42	GO:0005615	extracellular space
0.38	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

sp|Q86VX9|MON1A_HUMAN
Vacuolar fusion protein MON1 homolog A
Search

MON1A

0.96	Vacuolar fusion protein MON1 like protein A

0.64	GO:0016192	vesicle-mediated transport
0.64	GO:0019085	early viral transcription
0.63	GO:0019086	late viral transcription
0.61	GO:0009306	protein secretion
0.49	GO:0065009	regulation of molecular function
0.44	GO:0006879	cellular iron ion homeostasis
0.38	GO:0007130	synaptonemal complex assembly
0.36	GO:0045861	negative regulation of proteolysis

0.53	GO:0005085	guanyl-nucleotide exchange factor activity
0.38	GO:0008191	metalloendopeptidase inhibitor activity

0.71	GO:0035658	Mon1-Ccz1 complex
0.39	GO:0005829	cytosol
0.38	GO:0000795	synaptonemal complex
0.35	GO:0005576	extracellular region

sp|Q86VY4|TSYL5_HUMAN
Testis-specific Y-encoded-like protein 5
Search

0.95	Testis-specific Y-encoded-like protein 5

0.79	GO:0006334	nucleosome assembly
0.56	GO:0071480	cellular response to gamma radiation
0.55	GO:0051897	positive regulation of protein kinase B signaling
0.53	GO:0031398	positive regulation of protein ubiquitination
0.52	GO:0008284	positive regulation of cell proliferation
0.46	GO:0040008	regulation of growth

0.39

GO:0005515

protein binding

0.61

GO:0005634

nucleus

sp|Q86VY9|T200A_HUMAN
Transmembrane protein 200A
Search

TMEM200A

0.51	Transmembrane domain-containing protein (Fragment)

0.30

GO:0044425

membrane part

sp|Q86VZ1|P2RY8_HUMAN
P2Y purinoceptor 8
Search

P2RY8

0.97	Purinergic receptor P2Y, G-protein coupled, 8

0.84	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.69	GO:0070493	thrombin-activated receptor signaling pathway
0.65	GO:0007596	blood coagulation
0.50	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.49	GO:0035025	positive regulation of Rho protein signal transduction
0.34	GO:0006886	intracellular protein transport
0.33	GO:0032259	methylation
0.32	GO:0007218	neuropeptide signaling pathway
0.32	GO:0055085	transmembrane transport
0.32	GO:0035556	intracellular signal transduction

0.84	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.69	GO:0015057	thrombin-activated receptor activity
0.35	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.34	GO:0008171	O-methyltransferase activity
0.33	GO:0004983	neuropeptide Y receptor activity
0.32	GO:0022857	transmembrane transporter activity

0.42	GO:0005887	integral component of plasma membrane
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane

0.35

EC:3.6.1.19

GO:0047429

sp|Q86VZ2|WDR5B_HUMAN
WD repeat-containing protein 5B
Search

WDR5B

0.92	WD repeat-containing protein 5

0.75	GO:0043982	histone H4-K8 acetylation
0.75	GO:0043981	histone H4-K5 acetylation
0.74	GO:0043984	histone H4-K16 acetylation
0.72	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.71	GO:0043966	histone H3 acetylation
0.71	GO:0051568	histone H3-K4 methylation
0.66	GO:0060271	cilium assembly
0.65	GO:0001501	skeletal system development
0.43	GO:0031175	neuron projection development
0.39	GO:0045652	regulation of megakaryocyte differentiation

0.76	GO:0043996	histone acetyltransferase activity (H4-K8 specific)
0.76	GO:0046972	histone acetyltransferase activity (H4-K16 specific)
0.76	GO:0043995	histone acetyltransferase activity (H4-K5 specific)
0.71	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.71	GO:0140034	methylation-dependent protein binding
0.67	GO:0042393	histone binding
0.39	GO:0016905	myosin heavy chain kinase activity

0.72	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.72	GO:0044666	MLL3/4 complex
0.70	GO:0071339	MLL1 complex
0.69	GO:0048188	Set1C/COMPASS complex
0.68	GO:0036064	ciliary basal body
0.41	GO:0019013	viral nucleocapsid
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.39

EC:2.7.11.7

GO:0016905

sp|Q86VZ4|LRP11_HUMAN
Low-density lipoprotein receptor-related protein 11
Search

LRP11

0.93	Low-density lipoprotein receptor-related protein 11

0.58	GO:0035902	response to immobilization stress
0.55	GO:0033555	multicellular organismal response to stress
0.54	GO:0009612	response to mechanical stimulus
0.54	GO:0009414	response to water deprivation
0.53	GO:0009409	response to cold
0.52	GO:0042594	response to starvation
0.51	GO:0009408	response to heat
0.44	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0006897	endocytosis
0.34	GO:2000171	negative regulation of dendrite development

0.58	GO:0051219	phosphoprotein binding
0.45	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0008233	peptidase activity

0.34	GO:0005886	plasma membrane
0.33	GO:0005769	early endosome
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008233

sp|Q86VZ5|SMS1_HUMAN
Phosphatidylcholine:ceramide cholinephosphotransferase 1
Search

SGMS1

0.69	Phosphatidylcholine:ceramide cholinephosphotransferase 1

0.61	GO:0046513	ceramide biosynthetic process
0.56	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.53	GO:0006686	sphingomyelin biosynthetic process
0.40	GO:1905371	ceramide phosphoethanolamine metabolic process
0.40	GO:0006915	apoptotic process
0.39	GO:0006954	inflammatory response
0.38	GO:0071356	cellular response to tumor necrosis factor
0.38	GO:0071222	cellular response to lipopolysaccharide
0.37	GO:0010628	positive regulation of gene expression
0.36	GO:0016310	phosphorylation

0.64	GO:0033188	sphingomyelin synthase activity
0.62	GO:0002950	ceramide phosphoethanolamine synthase activity
0.53	GO:0047493	ceramide cholinephosphotransferase activity
0.36	GO:0016301	kinase activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.50	GO:0030173	integral component of Golgi membrane
0.47	GO:0030176	integral component of endoplasmic reticulum membrane
0.44	GO:0005887	integral component of plasma membrane
0.39	GO:0000138	Golgi trans cisterna
0.34	GO:0005634	nucleus

0.64	EC:2.7.8.27	GO:0033188
0.64	KEGG:R08969	GO:0033188

sp|Q86VZ6|JAZF1_HUMAN
Juxtaposed with another zinc finger protein 1
Search

JAZF1

0.97	Juxtaposed with another zinc finger protein 1

0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0007368	determination of left/right symmetry
0.42	GO:0060271	cilium assembly
0.35	GO:0006629	lipid metabolic process
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0045944	positive regulation of transcription by RNA polymerase II
0.32	GO:0055085	transmembrane transport

0.52	GO:0003714	transcription corepressor activity
0.51	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding
0.33	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.54	GO:0001650	fibrillar center
0.52	GO:0017053	transcriptional repressor complex
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q86W10|CP4Z1_HUMAN
Cytochrome P450 4Z1
Search

0.94	Fatty acid omega-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.42	GO:0006690	icosanoid metabolic process
0.42	GO:0033559	unsaturated fatty acid metabolic process
0.41	GO:0001676	long-chain fatty acid metabolic process
0.39	GO:1901569	fatty acid derivative catabolic process
0.39	GO:0048252	lauric acid metabolic process
0.38	GO:0009062	fatty acid catabolic process
0.38	GO:1901616	organic hydroxy compound catabolic process
0.37	GO:0003095	pressure natriuresis
0.37	GO:1901570	fatty acid derivative biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.64	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.43	GO:0103002	16-hydroxypalmitate dehydrogenase activity
0.35	GO:0050544	arachidonic acid binding
0.34	GO:0019825	oxygen binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0016324	apical plasma membrane
0.39	GO:0005615	extracellular space
0.38	GO:0031090	organelle membrane
0.34	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q86W11|ZSC30_HUMAN
Zinc finger and SCAN domain-containing protein 30
Search

ZSCAN30

0.86	Zinc finger and SCAN domain-containing protein 30

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.50	GO:0006351	transcription, DNA-templated
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0042552	myelination
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0022604	regulation of cell morphogenesis

0.55	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.55	GO:0005634	nucleus
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane

sp|Q86W24|NAL14_HUMAN
NACHT, LRR and PYD domains-containing protein 14
Search

NLRP12

0.89	NLR family pyrin domain containing 2

0.60	GO:0007283	spermatogenesis
0.56	GO:0008588	release of cytoplasmic sequestered NF-kappaB
0.56	GO:0050704	regulation of interleukin-1 secretion
0.56	GO:0045345	positive regulation of MHC class I biosynthetic process
0.56	GO:0045751	negative regulation of Toll signaling pathway
0.55	GO:0045409	negative regulation of interleukin-6 biosynthetic process
0.55	GO:0032692	negative regulation of interleukin-1 production
0.55	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.55	GO:0031953	negative regulation of protein autophosphorylation
0.54	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.41	GO:0019904	protein domain specific binding
0.39	GO:0019899	enzyme binding
0.37	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.36	GO:0019966	interleukin-1 binding

0.43	GO:0061702	inflammasome complex
0.39	GO:0031981	nuclear lumen
0.38	GO:0000781	chromosome, telomeric region
0.37	GO:0005794	Golgi apparatus

sp|Q86W25|NAL13_HUMAN
NACHT, LRR and PYD domains-containing protein 13
Search

NLRP13

0.95	NACHT, LRR and PYD domains-containing protein 13

0.49	GO:0008588	release of cytoplasmic sequestered NF-kappaB
0.49	GO:0045345	positive regulation of MHC class I biosynthetic process
0.49	GO:0045751	negative regulation of Toll signaling pathway
0.49	GO:0045409	negative regulation of interleukin-6 biosynthetic process
0.48	GO:0050711	negative regulation of interleukin-1 secretion
0.48	GO:0031953	negative regulation of protein autophosphorylation
0.47	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.47	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.46	GO:0050728	negative regulation of inflammatory response
0.46	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0032090	Pyrin domain binding
0.35	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.30	GO:0003824	catalytic activity

0.36	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0000781	chromosome, telomeric region
0.33	GO:0012505	endomembrane system
0.32	GO:0043234	protein complex

sp|Q86W26|NAL10_HUMAN
NACHT, LRR and PYD domains-containing protein 10
Search

NLRP10

0.95	NLR family pyrin domain containing 10

0.70	GO:0050704	regulation of interleukin-1 secretion
0.66	GO:0032730	positive regulation of interleukin-1 alpha production
0.66	GO:0032675	regulation of interleukin-6 production
0.65	GO:2000484	positive regulation of interleukin-8 secretion
0.64	GO:1900426	positive regulation of defense response to bacterium
0.62	GO:0050727	regulation of inflammatory response
0.61	GO:2000318	positive regulation of T-helper 17 type immune response
0.61	GO:0050829	defense response to Gram-negative bacterium
0.60	GO:0002827	positive regulation of T-helper 1 type immune response
0.56	GO:0050832	defense response to fungus

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0003924	GTPase activity
0.48	GO:0016887	ATPase activity
0.42	GO:0019904	protein domain specific binding
0.41	GO:0019899	enzyme binding
0.38	GO:0042802	identical protein binding

0.57	GO:0019897	extrinsic component of plasma membrane
0.49	GO:0061702	inflammasome complex
0.40	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.48

GO:0016887

sp|Q86W28|NALP8_HUMAN
NACHT, LRR and PYD domains-containing protein 8
Search

NLRP8

0.94	NACHT, LRR and PYD domains-containing protein 8

0.58	GO:0070997	neuron death
0.48	GO:0007283	spermatogenesis
0.46	GO:0002674	negative regulation of acute inflammatory response
0.46	GO:0050713	negative regulation of interleukin-1 beta secretion
0.45	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.45	GO:0050718	positive regulation of interleukin-1 beta secretion
0.44	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.44	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.44	GO:0071222	cellular response to lipopolysaccharide

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.41	GO:0042802	identical protein binding
0.39	GO:0008134	transcription factor binding
0.37	GO:0043565	sequence-specific DNA binding
0.30	GO:0003824	catalytic activity

0.47	GO:0061702	inflammasome complex
0.37	GO:0005634	nucleus
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005938	cell cortex
0.35	GO:0005576	extracellular region
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005739	mitochondrion
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part

sp|Q86W33|TPRA1_HUMAN
Transmembrane protein adipocyte-associated 1
Search

TPRA1

0.96	Transmembrane protein adipocyte-associated 1

0.60	GO:0040016	embryonic cleavage
0.55	GO:1901991	negative regulation of mitotic cell cycle phase transition
0.35	GO:0007568	aging
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0006629	lipid metabolic process

0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q86W34|AMZ2_HUMAN
Archaemetzincin-2
Search

AMZ2

0.97	Archaemetzincin-2

0.60

GO:0006508

proteolysis

0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding

sp|Q86W42|THOC6_HUMAN
THO complex subunit 6 homolog
Search

THOC6

0.96	THO complex subunit 6

0.86	GO:0046784	viral mRNA export from host cell nucleus
0.78	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0007417	central nervous system development
0.76	GO:0043066	negative regulation of apoptotic process
0.74	GO:0051028	mRNA transport
0.73	GO:0006405	RNA export from nucleus
0.53	GO:0010467	gene expression
0.48	GO:0006915	apoptotic process
0.45	GO:0016071	mRNA metabolic process
0.36	GO:0097659	nucleic acid-templated transcription

0.41	GO:0003723	RNA binding
0.37	GO:0005515	protein binding

0.83	GO:0000445	THO complex part of transcription export complex
0.79	GO:0000784	nuclear chromosome, telomeric region
0.78	GO:0016607	nuclear speck

sp|Q86W47|KCMB4_HUMAN
Calcium-activated potassium channel subunit beta-4
Search

KCNMB4

0.97	Calcium-activated potassium channel subunit beta-4

0.73	GO:0071805	potassium ion transmembrane transport
0.70	GO:0005513	detection of calcium ion
0.67	GO:0019228	neuronal action potential
0.48	GO:0007268	chemical synaptic transmission
0.44	GO:0065009	regulation of molecular function
0.37	GO:0046928	regulation of neurotransmitter secretion
0.37	GO:0019229	regulation of vasoconstriction

0.84	GO:0015269	calcium-activated potassium channel activity
0.52	GO:0015459	potassium channel regulator activity
0.36	GO:0005515	protein binding

0.61

GO:0008076

voltage-gated potassium channel complex

sp|Q86W50|MET16_HUMAN
Methyltransferase-like protein 16
Search

METTL16

0.82	Methyltransferase 10 domain containing (Fragment)

0.63	GO:0032259	methylation
0.61	GO:0120049	snRNA (adenine-N6)-methylation
0.56	GO:0061157	mRNA destabilization
0.56	GO:0048024	regulation of mRNA splicing, via spliceosome
0.54	GO:0016556	mRNA modification
0.50	GO:0006402	mRNA catabolic process
0.44	GO:0000154	rRNA modification
0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.36	GO:0000132	establishment of mitotic spindle orientation

0.63	GO:0008168	methyltransferase activity
0.61	GO:0030629	U6 snRNA 3'-end binding
0.58	GO:0035613	RNA stem-loop binding
0.47	GO:0140098	catalytic activity, acting on RNA
0.36	GO:0070840	dynein complex binding
0.34	GO:0046983	protein dimerization activity
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005634	nucleus
0.35	GO:0005875	microtubule associated complex
0.35	GO:0005815	microtubule organizing center
0.35	GO:0005874	microtubule
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.63

GO:0008168

sp|Q86W54|SPA24_HUMAN
Spermatogenesis-associated protein 24
Search

SPATA24

0.97	Spermatogenesis-associated protein 24

0.49	GO:0007283	spermatogenesis
0.46	GO:0030154	cell differentiation
0.45	GO:0007275	multicellular organism development
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.71	GO:0042803	protein homodimerization activity
0.53	GO:0003677	DNA binding

0.66	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q86W56|PARG_HUMAN
Poly(ADP-ribose) glycohydrolase
Search

PARG

0.86	Poly (ADP-ribose) glycohydrolase

0.63	GO:1990966	ATP generation from poly-ADP-D-ribose
0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0016045	detection of bacterium
0.36	GO:0045739	positive regulation of DNA repair
0.35	GO:0006974	cellular response to DNA damage stimulus
0.34	GO:0006334	nucleosome assembly
0.34	GO:0006468	protein phosphorylation

0.85	GO:0004649	poly(ADP-ribose) glycohydrolase activity
0.35	GO:0003682	chromatin binding
0.35	GO:0005515	protein binding
0.35	GO:0004683	calmodulin-dependent protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0005759	mitochondrial matrix
0.34	GO:0000785	chromatin
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.2.1.143

GO:0004649

sp|Q86W67|F228A_HUMAN
Protein FAM228A
Search

sp|Q86W74|ANR46_HUMAN
Ankyrin repeat domain-containing protein 46
Search

ANKRD46

0.97	Ankyrin repeat domain-containing protein 46

0.36

GO:0006886

intracellular protein transport

0.36

GO:0035091

phosphatidylinositol binding

0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q86W92|LIPB1_HUMAN
Liprin-beta-1
Search

PPFIBP1

0.92	PTPRF interacting protein binding protein 1

0.41	GO:0007155	cell adhesion
0.37	GO:0000187	activation of MAPK activity
0.36	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.36	GO:0048666	neuron development
0.36	GO:0018108	peptidyl-tyrosine phosphorylation

0.81	GO:0045296	cadherin binding
0.36	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005925	focal adhesion
0.40	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

EC:2.7.10.1

GO:0004714

sp|Q86WA6|BPHL_HUMAN
Valacyclovir hydrolase
Search

BPHL

0.75	Biphenyl hydrolase like

0.36	GO:1990966	ATP generation from poly-ADP-D-ribose
0.35	GO:0070926	regulation of ATP:ADP antiporter activity
0.35	GO:0060545	positive regulation of necroptotic process
0.35	GO:0097343	ripoptosome assembly
0.35	GO:0036289	peptidyl-serine autophosphorylation
0.35	GO:1905206	positive regulation of hydrogen peroxide-induced cell death
0.35	GO:1990000	amyloid fibril formation
0.35	GO:0097527	necroptotic signaling pathway
0.35	GO:0045651	positive regulation of macrophage differentiation
0.35	GO:0006805	xenobiotic metabolic process

0.47	GO:0016787	hydrolase activity
0.35	GO:0005123	death receptor binding
0.35	GO:0070513	death domain binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0032403	protein complex binding
0.34	GO:0042802	identical protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0015035	protein disulfide oxidoreductase activity
0.32	GO:0097367	carbohydrate derivative binding

0.46	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.35	GO:0031264	death-inducing signaling complex
0.35	GO:0097342	ripoptosome
0.35	GO:0031968	organelle outer membrane
0.34	GO:0043235	receptor complex
0.33	GO:0005634	nucleus

0.47

GO:0016787

sp|Q86WA8|LONP2_HUMAN
Lon protease homolog 2, peroxisomal
Search

LONP2

0.75	Lon protease homolog 2, peroxisomal

0.73	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.70	GO:0072663	establishment of protein localization to peroxisome
0.70	GO:0043574	peroxisomal transport
0.67	GO:0044743	protein transmembrane import into intracellular organelle
0.65	GO:0016485	protein processing
0.63	GO:0065002	intracellular protein transmembrane transport
0.62	GO:0006605	protein targeting
0.62	GO:0031998	regulation of fatty acid beta-oxidation
0.38	GO:0014070	response to organic cyclic compound

0.75	GO:0004176	ATP-dependent peptidase activity
0.68	GO:0004252	serine-type endopeptidase activity
0.59	GO:0002020	protease binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005102	receptor binding
0.33	GO:0043565	sequence-specific DNA binding

0.74	GO:0031907	microbody lumen
0.68	GO:0044439	peroxisomal part
0.46	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004252

sp|Q86WA9|S2611_HUMAN
Sodium-independent sulfate anion transporter
Search

SLC26A11

0.83	Sodium-independent sulfate anion transporter

0.75	GO:1902358	sulfate transmembrane transport
0.51	GO:0015701	bicarbonate transport
0.51	GO:0019532	oxalate transport
0.50	GO:0051453	regulation of intracellular pH
0.48	GO:0042391	regulation of membrane potential
0.47	GO:1902476	chloride transmembrane transport
0.34	GO:0016567	protein ubiquitination
0.32	GO:0051276	chromosome organization

0.78	GO:0008271	secondary active sulfate transmembrane transporter activity
0.52	GO:0015106	bicarbonate transmembrane transporter activity
0.51	GO:0019531	oxalate transmembrane transporter activity
0.50	GO:0015301	anion:anion antiporter activity
0.48	GO:0005254	chloride channel activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016887	ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005765	lysosomal membrane
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005783	endoplasmic reticulum
0.50	GO:0005654	nucleoplasm
0.44	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.32	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.33	EC:3.6.1.3	GO:0016887
0.34	KEGG:R03876	GO:0004842

sp|Q86WB0|NIPA_HUMAN
Nuclear-interacting partner of ALK
Search

ZC3HC1

0.91	Nuclear-interacting partner of ALK

0.52	GO:1901099	negative regulation of signal transduction in absence of ligand
0.51	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.50	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.42	GO:0016567	protein ubiquitination
0.41	GO:0051301	cell division
0.41	GO:0007049	cell cycle

0.63	GO:0008270	zinc ion binding
0.49	GO:0019901	protein kinase binding

0.61	GO:0005634	nucleus
0.45	GO:0012505	endomembrane system
0.43	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane

sp|Q86WB7|UN93A_HUMAN
Protein unc-93 homolog A
Search

UNC93A

0.97	Unc-93 homolog A (C. elegans)

0.36	GO:0055085	transmembrane transport
0.34	GO:0043266	regulation of potassium ion transport
0.34	GO:0006464	cellular protein modification process
0.34	GO:0006937	regulation of muscle contraction
0.33	GO:0008643	carbohydrate transport
0.33	GO:0065009	regulation of molecular function

0.34	GO:0015459	potassium channel regulator activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005886	plasma membrane
0.34	GO:0055120	striated muscle dense body
0.30	GO:0044425	membrane part

sp|Q86WC4|OSTM1_HUMAN
Osteopetrosis-associated transmembrane protein 1
Search

OSTM1

0.95	Osteopetrosis-associated transmembrane protein 1

0.63	GO:0030316	osteoclast differentiation
0.34	GO:0034220	ion transmembrane transport

0.34

GO:0005515

protein binding

0.52	GO:0005829	cytosol
0.38	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q86WC6|PPR27_HUMAN
Protein phosphatase 1 regulatory subunit 27
Search

PPP1R27

0.97	Dysferlin-interacting protein 1

0.76	GO:0010923	negative regulation of phosphatase activity
0.43	GO:0035308	negative regulation of protein dephosphorylation
0.42	GO:0043666	regulation of phosphoprotein phosphatase activity
0.39	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.38	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.38	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.38	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.38	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.38	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.37	GO:0070682	proteasome regulatory particle assembly

0.77	GO:0019902	phosphatase binding
0.43	GO:0004864	protein phosphatase inhibitor activity
0.38	GO:0008134	transcription factor binding
0.38	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.38	GO:0051427	hormone receptor binding
0.36	GO:0047389	glycerophosphocholine phosphodiesterase activity
0.36	GO:0002039	p53 binding
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0004067	asparaginase activity

0.42	GO:1905369	endopeptidase complex
0.38	GO:0043234	protein complex
0.38	GO:0005634	nucleus
0.37	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0005829	cytosol
0.35	GO:0005694	chromosome
0.33	GO:0000151	ubiquitin ligase complex
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.36	EC:3.1.4.2	GO:0047389
0.33	KEGG:R03876	GO:0004842

sp|Q86WD7|SPA9_HUMAN
Serpin A9
Search

SERPINA7

0.91	Thyroxine-binding globulin

0.56	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:0070327	thyroid hormone transport
0.41	GO:0007283	spermatogenesis
0.39	GO:0008211	glucocorticoid metabolic process
0.36	GO:0061107	seminal vesicle development
0.35	GO:0007338	single fertilization
0.35	GO:0006508	proteolysis
0.35	GO:0033189	response to vitamin A
0.35	GO:0051412	response to corticosterone
0.35	GO:0034695	response to prostaglandin E

0.58	GO:0004867	serine-type endopeptidase inhibitor activity
0.43	GO:0032190	acrosin binding
0.43	GO:0001972	retinoic acid binding
0.43	GO:0031210	phosphatidylcholine binding
0.42	GO:0002020	protease binding
0.39	GO:0005496	steroid binding
0.35	GO:0008233	peptidase activity
0.35	GO:0008201	heparin binding
0.35	GO:0015349	thyroid hormone transmembrane transporter activity
0.34	GO:0042562	hormone binding

0.73	GO:0005615	extracellular space
0.44	GO:0097182	protein C inhibitor-coagulation factor Xa complex
0.44	GO:0097183	protein C inhibitor-coagulation factor XI complex
0.44	GO:0097181	protein C inhibitor-coagulation factor V complex
0.44	GO:0036030	protein C inhibitor-plasma kallikrein complex
0.44	GO:0036028	protein C inhibitor-thrombin complex
0.44	GO:0036029	protein C inhibitor-KLK3 complex
0.44	GO:0036024	protein C inhibitor-TMPRSS7 complex
0.44	GO:0036025	protein C inhibitor-TMPRSS11E complex
0.44	GO:0036026	protein C inhibitor-PLAT complex

0.35

GO:0008233

sp|Q86WG3|ATCAY_HUMAN
Caytaxin
Search

ATCAY

0.97	Ataxia, cerebellar, Cayman type b

0.74	GO:2000212	negative regulation of glutamate metabolic process
0.62	GO:0031175	neuron projection development
0.60	GO:0032880	regulation of protein localization
0.50	GO:0032222	regulation of synaptic transmission, cholinergic
0.45	GO:0048311	mitochondrion distribution
0.38	GO:0035418	protein localization to synapse
0.36	GO:0006915	apoptotic process
0.34	GO:0055114	oxidation-reduction process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.67	GO:0019894	kinesin binding
0.45	GO:0050699	WW domain binding
0.37	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.36	GO:0005507	copper ion binding
0.36	GO:0016462	pyrophosphatase activity
0.36	GO:0042802	identical protein binding
0.35	GO:0015293	symporter activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.63	GO:0043005	neuron projection
0.51	GO:0031966	mitochondrial membrane
0.44	GO:0036477	somatodendritic compartment
0.43	GO:0120038	plasma membrane bounded cell projection part
0.43	GO:0045202	synapse
0.41	GO:0030054	cell junction
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.37

EC:1.4.3

GO:0016641

sp|Q86WG5|MTMRD_HUMAN
Myotubularin-related protein 13
Search

SBF2

0.92	SET binding factor 2

0.75	GO:0043087	regulation of GTPase activity
0.61	GO:0051262	protein tetramerization

0.79	GO:0019208	phosphatase regulator activity
0.64	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.63	GO:0019902	phosphatase binding
0.59	GO:0035091	phosphatidylinositol binding
0.58	GO:0042803	protein homodimerization activity

0.59	GO:0005774	vacuolar membrane
0.35	GO:0005829	cytosol

sp|Q86WH2|RASF3_HUMAN
Ras association domain-containing protein 3
Search

RASSF3

0.97	Ras association domain-containing protein 3

0.71	GO:0042981	regulation of apoptotic process
0.60	GO:0007165	signal transduction
0.47	GO:0070507	regulation of microtubule cytoskeleton organization
0.33	GO:0007050	cell cycle arrest

0.49	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding
0.33	GO:0017016	Ras GTPase binding

0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.36	GO:0015630	microtubule cytoskeleton
0.36	GO:0099513	polymeric cytoskeletal fiber
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q86WI0|LHPL1_HUMAN
Lipoma HMGIC fusion partner-like 1 protein
Search

0.96	LHFPL tetraspan subfamily member 1

0.30

GO:0044425

membrane part

sp|Q86WI1|PKHL1_HUMAN
Fibrocystin-L
Search

0.64	fibrocystin-L

0.46	GO:0021785	branchiomotor neuron axon guidance
0.46	GO:0048841	regulation of axon extension involved in axon guidance
0.44	GO:0071526	semaphorin-plexin signaling pathway
0.41	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.40	GO:0000272	polysaccharide catabolic process
0.33	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.33	GO:0018108	peptidyl-tyrosine phosphorylation
0.32	GO:0006413	translational initiation
0.30	GO:0006955	immune response

0.45	GO:0017154	semaphorin receptor activity
0.43	GO:0005509	calcium ion binding
0.40	GO:0008017	microtubule binding
0.33	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0003743	translation initiation factor activity
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.54	GO:0005929	cilium
0.39	GO:0005856	cytoskeleton
0.36	GO:0005886	plasma membrane
0.30	GO:0005615	extracellular space
0.30	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

EC:2.7.10.1

GO:0004714

sp|Q86WI3|NLRC5_HUMAN
Protein NLRC5
Search

NLRC5

0.94	NLR family CARD domain containing 5

0.85	GO:0045345	positive regulation of MHC class I biosynthetic process
0.85	GO:0060332	positive regulation of response to interferon-gamma
0.85	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.84	GO:0060334	regulation of interferon-gamma-mediated signaling pathway
0.80	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.74	GO:0045087	innate immune response
0.73	GO:0051607	defense response to virus
0.71	GO:0043549	regulation of kinase activity
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.71	GO:0060339	negative regulation of type I interferon-mediated signaling pathway

0.82	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005813	centrosome
0.65	GO:0005829	cytosol
0.58	GO:0005634	nucleus
0.32	GO:0048471	perinuclear region of cytoplasm

sp|Q86WJ1|CHD1L_HUMAN
Chromodomain-helicase-DNA-binding protein 1-like
Search

CHD1L

0.97	Chromodomain helicase DNA binding protein 1 like

0.76	GO:0006338	chromatin remodeling
0.68	GO:0032392	DNA geometric change
0.63	GO:0006974	cellular response to DNA damage stimulus
0.58	GO:0006259	DNA metabolic process

0.70	GO:0004003	ATP-dependent DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005654	nucleoplasm
0.54	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q86WK6|AMGO1_HUMAN
Amphoterin-induced protein 1
Search

AMIGO1

0.89	Adhesion molecule with Ig like domain 1

0.83	GO:0007413	axonal fasciculation
0.80	GO:0042552	myelination
0.69	GO:0007155	cell adhesion
0.63	GO:0051965	positive regulation of synapse assembly
0.61	GO:1901381	positive regulation of potassium ion transmembrane transport
0.50	GO:0065009	regulation of molecular function
0.44	GO:0043066	negative regulation of apoptotic process
0.43	GO:0007420	brain development
0.41	GO:0050772	positive regulation of axonogenesis
0.40	GO:0007409	axonogenesis

0.62	GO:0015459	potassium channel regulator activity
0.36	GO:0005515	protein binding

0.64	GO:0005887	integral component of plasma membrane
0.63	GO:0032809	neuronal cell body membrane
0.58	GO:0030425	dendrite
0.56	GO:0034705	potassium channel complex
0.41	GO:0043204	perikaryon
0.38	GO:0030424	axon
0.33	GO:0005634	nucleus

sp|Q86WK7|AMGO3_HUMAN
Amphoterin-induced protein 3
Search

AMIGO3

0.95	Adhesion molecule with Ig like domain 3

0.72	GO:0051965	positive regulation of synapse assembly
0.51	GO:0007413	axonal fasciculation
0.50	GO:0042552	myelination
0.48	GO:1901381	positive regulation of potassium ion transmembrane transport
0.46	GO:0007155	cell adhesion
0.42	GO:0065009	regulation of molecular function
0.35	GO:0043066	negative regulation of apoptotic process

0.48

GO:0015459

potassium channel regulator activity

0.49	GO:0032809	neuronal cell body membrane
0.46	GO:0030425	dendrite
0.45	GO:0008076	voltage-gated potassium channel complex

sp|Q86WK9|MPRA_HUMAN
Membrane progestin receptor alpha
Search

PAQR7

0.97	Membrane progestin receptor alpha-B

0.50	GO:0048545	response to steroid hormone
0.49	GO:0071396	cellular response to lipid
0.49	GO:0071407	cellular response to organic cyclic compound
0.49	GO:0009755	hormone-mediated signaling pathway
0.44	GO:0048477	oogenesis
0.42	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.42	GO:0000187	activation of MAPK activity
0.42	GO:0071695	anatomical structure maturation
0.42	GO:0048469	cell maturation
0.38	GO:0007275	multicellular organism development

0.52	GO:0005496	steroid binding
0.50	GO:0003707	steroid hormone receptor activity

0.42	GO:0005886	plasma membrane
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|Q86WN1|FCSD1_HUMAN
F-BAR and double SH3 domains protein 1
Search

FCHSD1

0.94	F-BAR and double SH3 domains protein 1

0.85	GO:0007274	neuromuscular synaptic transmission
0.77	GO:0030833	regulation of actin filament polymerization
0.39	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.39	GO:0001881	receptor recycling
0.37	GO:0051336	regulation of hydrolase activity
0.37	GO:0043085	positive regulation of catalytic activity
0.35	GO:0030835	negative regulation of actin filament depolymerization
0.35	GO:0032272	negative regulation of protein polymerization
0.35	GO:0007165	signal transduction
0.34	GO:0071420	cellular response to histamine

0.37	GO:0005096	GTPase activator activity
0.37	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.33	GO:0060090	molecular adaptor activity

0.84	GO:0031594	neuromuscular junction
0.82	GO:0055037	recycling endosome
0.35	GO:0008290	F-actin capping protein complex
0.34	GO:0072686	mitotic spindle
0.33	GO:0030479	actin cortical patch
0.32	GO:0005634	nucleus

sp|Q86WN2|IFNE_HUMAN
Interferon epsilon
Search

IFNE

0.96	Interferon-alphaomega

0.77	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.62	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.61	GO:0002323	natural killer cell activation involved in immune response
0.60	GO:0042100	B cell proliferation
0.60	GO:0002286	T cell activation involved in immune response
0.60	GO:0043330	response to exogenous dsRNA
0.59	GO:0042742	defense response to bacterium
0.59	GO:0030183	B cell differentiation
0.58	GO:0002250	adaptive immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.53	GO:0032403	protein complex binding
0.37	GO:0008811	chloramphenicol O-acetyltransferase activity

0.73

GO:0005615

extracellular space

0.37	EC:2.3.1.28	GO:0008811
0.37	KEGG:R03065	GO:0008811

sp|Q86WP2|GPBP1_HUMAN
Vasculin
Search

GPBP1

0.97	Z-linked GC-rich promoter binding protein 1

0.72	GO:0045893	positive regulation of transcription, DNA-templated
0.57	GO:0006351	transcription, DNA-templated
0.32	GO:0006915	apoptotic process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0042981	regulation of apoptotic process
0.32	GO:0019538	protein metabolic process

0.60	GO:0003700	DNA binding transcription factor activity
0.42	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0004197	cysteine-type endopeptidase activity

0.60	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.34	GO:0043233	organelle lumen
0.33	GO:0032991	macromolecular complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.32

EC:3.4.22

GO:0004197

sp|Q86WQ0|NR2CA_HUMAN
Nuclear receptor 2C2-associated protein
Search

NR2C2AP

0.97	Nuclear receptor 2C2-associated protein isoform B

0.40	GO:0006367	transcription initiation from RNA polymerase II promoter
0.37	GO:0007155	cell adhesion
0.34	GO:0042254	ribosome biogenesis
0.34	GO:0006396	RNA processing

0.39	GO:0005540	hyaluronic acid binding
0.36	GO:0005515	protein binding
0.34	GO:0016746	transferase activity, transferring acyl groups

0.68	GO:0005654	nucleoplasm
0.42	GO:0070062	extracellular exosome
0.35	GO:0005730	nucleolus

0.34

GO:0016746

sp|Q86WR0|CCD25_HUMAN
Coiled-coil domain-containing protein 25
Search

CCDC25

0.90	Coiled-coil domain-containing protein 25

0.42	GO:0043043	peptide biosynthetic process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0010467	gene expression
0.39	GO:0009059	macromolecule biosynthetic process

0.46	GO:0005515	protein binding
0.43	GO:0003735	structural constituent of ribosome

0.65	GO:0070062	extracellular exosome
0.42	GO:0005840	ribosome

sp|Q86WR6|CQ064_HUMAN
Uncharacterized protein C17orf64
Search

sp|Q86WR7|PRSR2_HUMAN
Proline and serine-rich protein 2
Search

PROSER2

0.97	Proline and serine-rich protein 2

0.58

GO:0005515

protein binding

sp|Q86WS3|OOSP2_HUMAN
Oocyte-secreted protein 2
Search

OOSP2

0.97	Oocyte-secreted protein 2

0.66

GO:0005576

extracellular region

sp|Q86WS4|CL040_HUMAN
Uncharacterized protein C12orf40
Search

sp|Q86WS5|TMPSC_HUMAN
Transmembrane protease serine 12
Search

TMPRSS12

0.82	Brain-specific serine protease 4

0.61	GO:0006508	proteolysis
0.44	GO:0006898	receptor-mediated endocytosis
0.36	GO:0007340	acrosome reaction
0.35	GO:0007596	blood coagulation
0.35	GO:0051604	protein maturation
0.35	GO:0006887	exocytosis
0.34	GO:0044256	protein digestion
0.34	GO:0007190	activation of adenylate cyclase activity
0.34	GO:0016310	phosphorylation
0.34	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan

0.69	GO:0004252	serine-type endopeptidase activity
0.47	GO:0005044	scavenger receptor activity
0.34	GO:0016301	kinase activity
0.34	GO:0005537	mannose binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0008201	heparin binding
0.32	GO:0005515	protein binding

0.40	GO:0001669	acrosomal vesicle
0.36	GO:0043083	synaptic cleft
0.36	GO:0043195	terminal bouton
0.35	GO:0030425	dendrite
0.34	GO:0005903	brush border
0.33	GO:0044437	vacuolar part
0.33	GO:0044433	cytoplasmic vesicle part
0.33	GO:0005886	plasma membrane
0.33	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005615	extracellular space

0.69

GO:0004252

sp|Q86WT1|TT30A_HUMAN
Tetratricopeptide repeat protein 30A
Search

0.45	Phosphodiesterase

0.81	GO:0042073	intraciliary transport
0.76	GO:0060271	cilium assembly
0.60	GO:0036372	opsin transport
0.59	GO:0018095	protein polyglutamylation
0.56	GO:0001736	establishment of planar polarity
0.55	GO:0007368	determination of left/right symmetry
0.37	GO:0007165	signal transduction

0.62	GO:0070738	tubulin-glycine ligase activity
0.44	GO:0005215	transporter activity
0.41	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.36	GO:0005515	protein binding
0.36	GO:0046872	metal ion binding

0.77	GO:0030992	intraciliary transport particle B
0.74	GO:0005929	cilium
0.58	GO:0005881	cytoplasmic microtubule
0.57	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.44	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

0.62

EC:6.3.2

GO:0070738

sp|Q86WT6|TRI69_HUMAN
E3 ubiquitin-protein ligase TRIM69
Search

TRIM69

0.95	Tripartite motif-containing protein 69

0.58	GO:0016567	protein ubiquitination
0.41	GO:0006915	apoptotic process
0.38	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.37	GO:2001235	positive regulation of apoptotic signaling pathway
0.34	GO:0032526	response to retinoic acid
0.34	GO:0007275	multicellular organism development
0.32	GO:0010508	positive regulation of autophagy
0.32	GO:0009405	pathogenesis

0.58	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0046872	metal ion binding
0.42	GO:0016874	ligase activity
0.36	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0090729	toxin activity

0.62	GO:0016607	nuclear speck
0.42	GO:0005737	cytoplasm
0.34	GO:0005694	chromosome
0.32	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.42	EC:6	GO:0016874
0.58	KEGG:R03876	GO:0004842

sp|Q86WU2|LDHD_HUMAN
Probable D-lactate dehydrogenase, mitochondrial
Search

LDHD

0.66	Lactate dehydrogenase D

0.53

GO:0055114

oxidation-reduction process

0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.52	GO:0005739	mitochondrion
0.35	GO:0019866	organelle inner membrane

0.65

EC:1.1

GO:0016614

sp|Q86WV1|SKAP1_HUMAN
Src kinase-associated phosphoprotein 1
Search

SKAP1

0.95	Src kinase-associated phosphoprotein 1

0.62	GO:0002757	immune response-activating signal transduction
0.58	GO:0002768	immune response-regulating cell surface receptor signaling pathway
0.57	GO:0072659	protein localization to plasma membrane
0.54	GO:0045785	positive regulation of cell adhesion
0.54	GO:0048522	positive regulation of cellular process
0.52	GO:0010557	positive regulation of macromolecule biosynthetic process
0.52	GO:0010628	positive regulation of gene expression
0.52	GO:0051173	positive regulation of nitrogen compound metabolic process
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0023056	positive regulation of signaling

0.61	GO:0042169	SH2 domain binding
0.58	GO:0019903	protein phosphatase binding
0.56	GO:0019901	protein kinase binding
0.55	GO:0005070	SH3/SH2 adaptor activity
0.51	GO:0016301	kinase activity
0.39	GO:0032403	protein complex binding
0.36	GO:0017124	SH3 domain binding
0.34	GO:0043565	sequence-specific DNA binding

0.60	GO:0042101	T cell receptor complex
0.54	GO:0005829	cytosol
0.54	GO:0005911	cell-cell junction
0.50	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|Q86WV5|TEN1L_HUMAN
CST complex subunit TEN1
Search

TEN1

0.97	CST complex subunit TEN1

0.47	GO:0032211	negative regulation of telomere maintenance via telomerase
0.40	GO:0016233	telomere capping

0.74	GO:0003697	single-stranded DNA binding
0.45	GO:0042162	telomeric DNA binding
0.36	GO:0005515	protein binding

0.85

GO:1990879

CST complex

sp|Q86WV6|STING_HUMAN
Stimulator of interferon genes protein
Search

TMEM173

0.97	Stimulator of interferon genes

0.85	GO:0032481	positive regulation of type I interferon production
0.82	GO:0002218	activation of innate immune response
0.66	GO:0032608	interferon-beta production
0.63	GO:0033160	positive regulation of protein import into nucleus, translocation
0.63	GO:0002230	positive regulation of defense response to virus by host
0.62	GO:0071360	cellular response to exogenous dsRNA
0.61	GO:0042993	positive regulation of transcription factor import into nucleus
0.60	GO:0032092	positive regulation of protein binding
0.59	GO:0035458	cellular response to interferon-beta
0.57	GO:0051607	defense response to virus

0.76	GO:0035438	cyclic-di-GMP binding
0.67	GO:0061507	cyclic-GMP-AMP binding
0.56	GO:0019901	protein kinase binding
0.55	GO:0042803	protein homodimerization activity
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0008134	transcription factor binding

0.56	GO:0005741	mitochondrial outer membrane
0.55	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005789	endoplasmic reticulum membrane
0.53	GO:0042579	microbody
0.50	GO:0005794	Golgi apparatus
0.37	GO:0030667	secretory granule membrane
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q86WW8|COA5_HUMAN
Cytochrome c oxidase assembly factor 5
Search

COA5

0.91	Mitochondrial cytochrome c oxidase assembly factor 5

0.65	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.39	GO:0006487	protein N-linked glycosylation
0.36	GO:0005975	carbohydrate metabolic process
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.39	GO:0008375	acetylglucosaminyltransferase activity
0.36	GO:0005515	protein binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.60	GO:0005739	mitochondrion
0.36	GO:0031970	organelle envelope lumen
0.36	GO:1905369	endopeptidase complex
0.36	GO:0031301	integral component of organelle membrane
0.34	GO:0043234	protein complex
0.34	GO:0019866	organelle inner membrane

0.39

GO:0008375

sp|Q86WX3|AROS_HUMAN
Active regulator of SIRT1
Search

RPS19BP1

0.95	Active regulator of SIRT1

0.70	GO:0019899	enzyme binding
0.43	GO:0003723	RNA binding

0.73	GO:0005730	nucleolus
0.70	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol

sp|Q86WZ0|HEAT4_HUMAN
HEAT repeat-containing protein 4
Search

HEATR4

0.97	LOW QUALITY PROTEIN: HEAT repeat-containing protein 4

sp|Q86WZ6|ZN227_HUMAN
Zinc finger protein 227
Search

0.65	Zinc finger protein 227

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.36	GO:0010467	gene expression
0.36	GO:0097659	nucleic acid-templated transcription
0.36	GO:0034645	cellular macromolecule biosynthetic process
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.33	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.45	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003735	structural constituent of ribosome
0.30	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.37	GO:0031974	membrane-enclosed lumen
0.37	GO:0043227	membrane-bounded organelle
0.35	GO:0044422	organelle part
0.34	GO:1990904	ribonucleoprotein complex
0.34	GO:0043228	non-membrane-bounded organelle

sp|Q86X02|CDR2L_HUMAN
Cerebellar degeneration-related protein 2-like
Search

CDR2L

0.97	Cerebellar degeneration related protein 2 like

0.55

GO:0006415

translational termination

0.55	GO:0003747	translation release factor activity
0.46	GO:0005515	protein binding

0.36

GO:0005737

cytoplasm

sp|Q86X10|RLGPB_HUMAN
Ral GTPase-activating protein subunit beta
Search

RALGAPB

0.92	Ral GTPase activating protein non-catalytic beta subunit

0.75	GO:0051056	regulation of small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.38	GO:0032484	Ral protein signal transduction
0.37	GO:0060178	regulation of exocyst localization

0.75	GO:0005096	GTPase activator activity
0.51	GO:0046982	protein heterodimerization activity

0.33

GO:0005829

cytosol

sp|Q86X19|TMM17_HUMAN
Transmembrane protein 17
Search

TMEM17

0.97	Transmembrane protein 17

0.57	GO:1905515	non-motile cilium assembly
0.55	GO:0007224	smoothened signaling pathway

0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.57	GO:0036038	MKS complex
0.57	GO:0060170	ciliary membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q86X24|HORM1_HUMAN
HORMA domain-containing protein 1
Search

HORMAD1

0.94	LOW QUALITY PROTEIN: HORMA domain-containing protein 2

0.85	GO:0051177	meiotic sister chromatid cohesion
0.82	GO:0060629	regulation of homologous chromosome segregation
0.80	GO:0051598	meiotic recombination checkpoint
0.78	GO:0042138	meiotic DNA double-strand break formation
0.77	GO:0007130	synaptonemal complex assembly
0.74	GO:0001824	blastocyst development
0.73	GO:0048477	oogenesis
0.72	GO:0007283	spermatogenesis

0.36

GO:0005515

protein binding

0.82	GO:0000795	synaptonemal complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q86X27|RGPS2_HUMAN
Ras-specific guanine nucleotide-releasing factor RalGPS2
Search

RALGPS2

0.92	Ras-specific guanine nucleotide-releasing factor RalGPS2

0.86	GO:0032485	regulation of Ral protein signal transduction
0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function

0.75

GO:0005085

guanyl-nucleotide exchange factor activity

0.45	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane

sp|Q86X29|LSR_HUMAN
Lipolysis-stimulated lipoprotein receptor
Search

LSR

0.94	Lipolysis-stimulated lipoprotein receptor

0.64	GO:1904274	tricellular tight junction assembly
0.63	GO:0061833	protein localization to tricellular tight junction
0.61	GO:0060856	establishment of blood-brain barrier
0.58	GO:0001889	liver development
0.49	GO:0031016	pancreas development
0.47	GO:0048873	homeostasis of number of cells within a tissue
0.47	GO:0030073	insulin secretion
0.46	GO:0009749	response to glucose
0.42	GO:0007492	endoderm development
0.40	GO:0019216	regulation of lipid metabolic process

0.38	GO:0017129	triglyceride binding
0.37	GO:0030169	low-density lipoprotein particle binding
0.37	GO:0030228	lipoprotein particle receptor activity
0.37	GO:0005504	fatty acid binding
0.36	GO:0005515	protein binding

0.61	GO:0061689	tricellular tight junction
0.43	GO:0005886	plasma membrane
0.43	GO:0034362	low-density lipoprotein particle
0.42	GO:0042627	chylomicron
0.42	GO:0034361	very-low-density lipoprotein particle
0.39	GO:0070062	extracellular exosome
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|Q86X40|LRC28_HUMAN
Leucine-rich repeat-containing protein 28
Search

LRRC28

0.97	Leucine-rich repeat-containing protein 28

0.61

GO:0007165

signal transduction

0.56

GO:0005886

plasma membrane

sp|Q86X45|TILB_HUMAN
Protein tilB homolog
Search

LRRC6

0.97	Leucine-rich repeat-containing protein 6

0.86	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.85	GO:0036158	outer dynein arm assembly
0.85	GO:0036159	inner dynein arm assembly
0.84	GO:0044458	motile cilium assembly
0.83	GO:0030317	flagellated sperm motility
0.83	GO:0008584	male gonad development

0.37	GO:0005515	protein binding
0.34	GO:0030246	carbohydrate binding

0.76	GO:0005929	cilium
0.49	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q86X51|CX067_HUMAN
Uncharacterized protein CXorf67
Search

sp|Q86X52|CHSS1_HUMAN
Chondroitin sulfate synthase 1
Search

CHSY1

0.55	Chondroitin sulfate synthase 1

0.57	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.55	GO:0051216	cartilage development
0.54	GO:0030204	chondroitin sulfate metabolic process
0.53	GO:0030279	negative regulation of ossification
0.53	GO:0045880	positive regulation of smoothened signaling pathway
0.52	GO:0009954	proximal/distal pattern formation
0.52	GO:0009887	animal organ morphogenesis
0.51	GO:0060348	bone development
0.51	GO:0051923	sulfation
0.48	GO:0048468	cell development

0.85	GO:0008376	acetylgalactosaminyltransferase activity
0.40	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
0.36	GO:0008378	galactosyltransferase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0004252	serine-type endopeptidase activity

0.81	GO:0032580	Golgi cisterna membrane
0.45	GO:0005576	extracellular region
0.36	GO:0030176	integral component of endoplasmic reticulum membrane

0.85

GO:0008376

sp|Q86X53|ERIC1_HUMAN
Glutamate-rich protein 1
Search

ERICH1

0.76	Glutamate-rich protein 1

sp|Q86X55|CARM1_HUMAN
Histone-arginine methyltransferase CARM1
Search

CARM1

0.94	Coactivator-associated arginine methyltransferase 1-a

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.63	GO:0003420	regulation of growth plate cartilage chondrocyte proliferation
0.60	GO:0030520	intracellular estrogen receptor signaling pathway
0.59	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.59	GO:0071168	protein localization to chromatin
0.59	GO:0045595	regulation of cell differentiation
0.58	GO:0060350	endochondral bone morphogenesis
0.58	GO:0018195	peptidyl-arginine modification
0.58	GO:0032091	negative regulation of protein binding

0.64	GO:0035642	histone methyltransferase activity (H3-R17 specific)
0.62	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity
0.58	GO:0001105	RNA polymerase II transcription coactivator activity
0.58	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.58	GO:0070577	lysine-acetylated histone binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.53	GO:0042803	protein homodimerization activity

0.53	GO:0090575	RNA polymerase II transcription factor complex
0.51	GO:0005829	cytosol
0.51	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|Q86X59|CQ082_HUMAN
Putative uncharacterized protein C17orf82
Search

sp|Q86X60|FA72B_HUMAN
Protein FAM72B
Search

0.61	GO:0031551	regulation of brain-derived neurotrophic factor-activated receptor activity
0.59	GO:0031549	negative regulation of brain-derived neurotrophic factor receptor signaling pathway
0.55	GO:0061099	negative regulation of protein tyrosine kinase activity
0.55	GO:2000272	negative regulation of receptor activity
0.53	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.51	GO:0043065	positive regulation of apoptotic process

0.41	GO:0005515	protein binding
0.38	GO:0019706	protein-cysteine S-palmitoyltransferase activity

0.62	GO:0005829	cytosol
0.53	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.38

GO:0019706

sp|Q86X67|NUD13_HUMAN
Nucleoside diphosphate-linked moiety X motif 13
Search

NUDT13

0.97	Nucleoside diphosphate-linked moiety X motif 13

0.36

GO:0015949

nucleobase-containing small molecule interconversion

0.52	GO:0046872	metal ion binding
0.51	GO:0016787	hydrolase activity

0.39	GO:0005739	mitochondrion
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

0.51

GO:0016787

sp|Q86X76|NIT1_HUMAN
Nitrilase homolog 1
Search

NIT1

0.56	Deaminated glutathione amidase

0.45	GO:0006807	nitrogen compound metabolic process
0.36	GO:1901837	negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.36	GO:0046697	decidualization
0.36	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.35	GO:0042177	negative regulation of protein catabolic process
0.35	GO:0046686	response to cadmium ion
0.33	GO:0046434	organophosphate catabolic process
0.32	GO:0046700	heterocycle catabolic process
0.32	GO:1901361	organic cyclic compound catabolic process
0.32	GO:0019439	aromatic compound catabolic process

0.37	GO:0016787	hydrolase activity
0.34	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0003676	nucleic acid binding
0.32	GO:0046872	metal ion binding

0.43	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0009536	plastid
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol

0.37

GO:0016787

sp|Q86X83|COMD2_HUMAN
COMM domain-containing protein 2
Search

COMMD2

0.97	COMM domain-containing protein 2

0.52	GO:0097659	nucleic acid-templated transcription
0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.49	GO:0010467	gene expression
0.48	GO:0034645	cellular macromolecule biosynthetic process
0.40	GO:0009072	aromatic amino acid family metabolic process

0.45	GO:0005515	protein binding
0.44	GO:0004334	fumarylacetoacetase activity

0.45	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.44	EC:3.7.1.2	GO:0004334
0.44	KEGG:R01364	GO:0004334

sp|Q86X95|CIR1_HUMAN
Corepressor interacting with RBPJ 1
Search

CIR1

0.87	Corepressor interacting with RBPJ 1

0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:0008380	RNA splicing
0.45	GO:0006397	mRNA processing
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0006351	transcription, DNA-templated
0.38	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0022900	electron transport chain

0.77	GO:0019901	protein kinase binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.41	GO:0003714	transcription corepressor activity
0.40	GO:0042826	histone deacetylase binding
0.35	GO:0020037	heme binding
0.35	GO:0009055	electron transfer activity
0.35	GO:0046872	metal ion binding
0.35	GO:0046982	protein heterodimerization activity
0.33	GO:0003676	nucleic acid binding

0.81	GO:0000118	histone deacetylase complex
0.79	GO:0016607	nuclear speck
0.77	GO:0005813	centrosome
0.59	GO:0043234	protein complex
0.37	GO:0005737	cytoplasm

sp|Q86XA0|MET23_HUMAN
Methyltransferase-like protein 23
Search

METTL23

0.90	Major facilitator superfamily domain containing 11

0.58	GO:0032259	methylation
0.56	GO:0050890	cognition
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0018205	peptidyl-lysine modification
0.34	GO:0008213	protein alkylation

0.59	GO:0008168	methyltransferase activity
0.54	GO:0031072	heat shock protein binding
0.52	GO:0008134	transcription factor binding
0.36	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0003723	RNA binding
0.33	GO:0140096	catalytic activity, acting on a protein

0.46	GO:0005634	nucleus
0.45	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.59

GO:0008168

sp|Q86XA9|HTR5A_HUMAN
HEAT repeat-containing protein 5A
Search

HEATR5A

0.87	HEAT repeat-containing protein 5A

0.46	GO:0043043	peptide biosynthetic process
0.44	GO:0044267	cellular protein metabolic process
0.43	GO:0010467	gene expression
0.42	GO:0009059	macromolecule biosynthetic process

0.48

GO:0003735

structural constituent of ribosome

0.47	GO:0070062	extracellular exosome
0.47	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q86XD5|F131B_HUMAN
Protein FAM131B
Search

sp|Q86XD8|ZFAN4_HUMAN
AN1-type zinc finger protein 4
Search

ZFAND4

0.97	AN1-type zinc finger and ubiquitin domain-containing protein 1

0.63

GO:0008270

zinc ion binding

0.30

GO:0044425

membrane part

sp|Q86XE0|SNX32_HUMAN
Sorting nexin-32
Search

SNX6

0.75	Sorting nexin

0.63	GO:0015031	protein transport
0.62	GO:0046907	intracellular transport
0.62	GO:0034613	cellular protein localization
0.49	GO:0016050	vesicle organization
0.46	GO:0006897	endocytosis
0.37	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.37	GO:1903593	regulation of histamine secretion by mast cell
0.37	GO:0016241	regulation of macroautophagy
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity

0.75	GO:0035091	phosphatidylinositol binding
0.44	GO:0034713	type I transforming growth factor beta receptor binding
0.39	GO:0034452	dynactin binding
0.36	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0003779	actin binding

0.50	GO:0005768	endosome
0.47	GO:0019898	extrinsic component of membrane
0.43	GO:0005764	lysosome
0.38	GO:0030904	retromer complex
0.37	GO:0044433	cytoplasmic vesicle part
0.37	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.34	GO:0015629	actin cytoskeleton

sp|Q86XE3|MICU3_HUMAN
Calcium uptake protein 3, mitochondrial
Search

MICU3

0.92	Calcium uptake protein 3, mitochondrial

0.38

GO:0006851

mitochondrial calcium ion transmembrane transport

0.70

GO:0005509

calcium ion binding

0.36	GO:0005739	mitochondrion
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q86XE5|HOGA1_HUMAN
4-hydroxy-2-oxoglutarate aldolase, mitochondrial
Search

HOGA1

0.58	N-acetylneuraminate lyase

0.60	GO:0019470	4-hydroxyproline catabolic process
0.55	GO:0009436	glyoxylate catabolic process
0.54	GO:0042866	pyruvate biosynthetic process
0.54	GO:0033609	oxalate metabolic process
0.33	GO:0015711	organic anion transport
0.32	GO:0055085	transmembrane transport

0.61	GO:0016829	lyase activity
0.50	GO:0042803	protein homodimerization activity
0.33	GO:0008514	organic anion transmembrane transporter activity

0.45	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005887	integral component of plasma membrane

0.61

EC:4

GO:0016829

sp|Q86XF0|DYR2_HUMAN
Dihydrofolate reductase 2, mitochondrial
Search

DHFR

0.43	Viral dihydrofolate reductase

0.74	GO:0046654	tetrahydrofolate biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.48	GO:0031427	response to methotrexate
0.47	GO:0046146	tetrahydrobiopterin metabolic process
0.47	GO:0034312	diol biosynthetic process
0.47	GO:0051000	positive regulation of nitric-oxide synthase activity
0.47	GO:2000121	regulation of removal of superoxide radicals
0.46	GO:0046452	dihydrofolate metabolic process
0.45	GO:0003232	bulbus arteriosus development
0.45	GO:0046655	folic acid metabolic process

0.78	GO:0004146	dihydrofolate reductase activity
0.47	GO:0051870	methotrexate binding
0.46	GO:0003729	mRNA binding
0.46	GO:0000900	translation repressor activity, nucleic acid binding
0.44	GO:0005542	folic acid binding
0.43	GO:0070402	NADPH binding
0.42	GO:0051871	dihydrofolic acid binding
0.37	GO:0033560	folate reductase activity
0.34	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0004386	helicase activity

0.43	GO:0005739	mitochondrion
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005829	cytosol
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:1.5.1.3

GO:0004146

sp|Q86XF7|ZN575_HUMAN
Zinc finger protein 575
Search

ZNF575

0.83	Zinc finger protein 575

0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.35	GO:0070941	eisosome assembly
0.32	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.44	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity

0.41	GO:0005634	nucleus
0.35	GO:0032126	eisosome
0.35	GO:0005876	spindle microtubule
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q86XG9|NBPF5_HUMAN
Putative neuroblastoma breakpoint family member 5
Search

0.88	Neuroblastoma breakpoint family member 9

0.49	GO:1903955	positive regulation of protein targeting to mitochondrion
0.36	GO:0007616	long-term memory

0.40	GO:0005509	calcium ion binding
0.37	GO:0003723	RNA binding

0.48

GO:0005737

cytoplasm

sp|Q86XH1|IQCA1_HUMAN
IQ and AAA domain-containing protein 1
Search

IQCA1

0.93	IQ motif-containing with AAA domain

0.34	GO:0016567	protein ubiquitination
0.34	GO:0035556	intracellular signal transduction

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.32

GO:0005622

intracellular

sp|Q86XI2|CNDG2_HUMAN
Condensin-2 complex subunit G2
Search

NCAPG2

0.95	Non-SMC condensin II complex subunit G2

0.57	GO:0001833	inner cell mass cell proliferation
0.38	GO:0030261	chromosome condensation
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle

0.59	GO:0140034	methylation-dependent protein binding
0.57	GO:0042393	histone binding
0.36	GO:0043425	bHLH transcription factor binding

0.61	GO:0005634	nucleus
0.56	GO:0000796	condensin complex
0.50	GO:0070013	intracellular organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q86XI6|PPR3B_HUMAN
Protein phosphatase 1 regulatory subunit 3B
Search

PPP1R3B

0.88	Protein phosphatase 1 regulatory subunit

0.84	GO:0005981	regulation of glycogen catabolic process
0.77	GO:0043666	regulation of phosphoprotein phosphatase activity
0.71	GO:0005977	glycogen metabolic process
0.39	GO:0005979	regulation of glycogen biosynthetic process
0.37	GO:0006470	protein dephosphorylation
0.37	GO:0009250	glucan biosynthetic process

0.79	GO:0019888	protein phosphatase regulator activity
0.39	GO:0019899	enzyme binding
0.37	GO:0004721	phosphoprotein phosphatase activity

0.78	GO:0000164	protein phosphatase type 1 complex
0.40	GO:0042587	glycogen granule
0.34	GO:0043231	intracellular membrane-bounded organelle

0.37

EC:3.1.3.16

GO:0004721

sp|Q86XI8|CS068_HUMAN
Uncharacterized protein C19orf68
Search

sp|Q86XJ0|CAHM3_HUMAN
Calcium homeostasis modulator protein 3
Search

CALHM3

0.96	Calcium homeostasis modulator protein 3

0.53	GO:0050917	sensory perception of umami taste
0.52	GO:0050916	sensory perception of sweet taste
0.51	GO:0098655	cation transmembrane transport
0.51	GO:0050913	sensory perception of bitter taste
0.50	GO:0015867	ATP transport
0.48	GO:0051260	protein homooligomerization
0.48	GO:0034765	regulation of ion transmembrane transport
0.47	GO:0006816	calcium ion transport
0.42	GO:0098660	inorganic ion transmembrane transport

0.62	GO:0005227	calcium activated cation channel activity
0.57	GO:0022832	voltage-gated channel activity
0.48	GO:0005262	calcium channel activity
0.46	GO:0042802	identical protein binding

0.48	GO:0005887	integral component of plasma membrane
0.34	GO:0005789	endoplasmic reticulum membrane

sp|Q86XJ1|GA2L3_HUMAN
GAS2-like protein 3
Search

GAS2L3

0.97	Growth arrest-specific 2 like 3

0.67	GO:0000226	microtubule cytoskeleton organization
0.65	GO:0030036	actin cytoskeleton organization
0.57	GO:0006915	apoptotic process
0.40	GO:0021923	cell proliferation in hindbrain ventricular zone
0.39	GO:0021591	ventricular system development
0.36	GO:0007050	cell cycle arrest
0.34	GO:0008360	regulation of cell shape

0.74	GO:0008017	microtubule binding
0.65	GO:0003779	actin binding

0.68	GO:0005856	cytoskeleton
0.37	GO:0099512	supramolecular fiber
0.35	GO:0044446	intracellular organelle part
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q86XK2|FBX11_HUMAN
F-box only protein 11
Search

FBXO11

0.74	F-box only protein 11

0.73	GO:0016567	protein ubiquitination
0.51	GO:0035246	peptidyl-arginine N-methylation
0.50	GO:0007605	sensory perception of sound
0.39	GO:0043687	post-translational protein modification
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006355	regulation of transcription, DNA-templated

0.61	GO:0008270	zinc ion binding
0.52	GO:0016274	protein-arginine N-methyltransferase activity
0.47	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.76	GO:0000151	ubiquitin ligase complex
0.47	GO:0005730	nucleolus
0.45	GO:0005829	cytosol
0.39	GO:0005694	chromosome

0.52	EC:2.1.1	GO:0016274
0.47	KEGG:R03876	GO:0004842

sp|Q86XK3|SFR1_HUMAN
Swi5-dependent recombination DNA repair protein 1 homolog
Search

SFR1

0.97	Swi5-dependent recombination DNA repair protein 1

0.85	GO:0071391	cellular response to estrogen stimulus
0.76	GO:0000724	double-strand break repair via homologous recombination
0.72	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0006351	transcription, DNA-templated

0.84	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.38	GO:0005515	protein binding

0.87	GO:0032798	Swi5-Sfr1 complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q86XK7|VSIG1_HUMAN
V-set and immunoglobulin domain-containing protein 1
Search

VSIG1

0.97	V-set and immunoglobulin domain-containing protein 1

0.85	GO:0030277	maintenance of gastrointestinal epithelium
0.85	GO:0003382	epithelial cell morphogenesis
0.36	GO:0048565	digestive tract development
0.32	GO:0006508	proteolysis

0.32	GO:0017171	serine hydrolase activity
0.32	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.55	GO:0005886	plasma membrane
0.36	GO:0005881	cytoplasmic microtubule
0.35	GO:0005923	bicellular tight junction
0.30	GO:0016021	integral component of membrane

sp|Q86XL3|ANKL2_HUMAN
Ankyrin repeat and LEM domain-containing protein 2
Search

ANKLE2

0.96	Ankyrin repeat and LEM domain-containing protein 2

0.85	GO:0007084	mitotic nuclear envelope reassembly
0.84	GO:0035307	positive regulation of protein dephosphorylation
0.53	GO:0007417	central nervous system development
0.53	GO:0043066	negative regulation of apoptotic process
0.52	GO:0042326	negative regulation of phosphorylation
0.37	GO:0051301	cell division
0.36	GO:0043666	regulation of phosphoprotein phosphatase activity

0.85	GO:0051721	protein phosphatase 2A binding
0.36	GO:0019888	protein phosphatase regulator activity

0.53

GO:0030176

integral component of endoplasmic reticulum membrane

sp|Q86XM0|CTSRD_HUMAN
Cation channel sperm-associated protein subunit delta
Search

CATSPERD

0.97	Cation channel sperm associated auxiliary subunit delta

0.55	GO:0048240	sperm capacitation
0.54	GO:0030317	flagellated sperm motility
0.47	GO:0007275	multicellular organism development
0.44	GO:0032570	response to progesterone
0.43	GO:0035036	sperm-egg recognition

0.38

GO:0005515

protein binding

0.85	GO:0036128	CatSper complex
0.55	GO:0097228	sperm principal piece

sp|Q86XN6|ZN761_HUMAN
Zinc finger protein 761
Search

0.60	Zinc finger protein 845

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity

0.46	GO:0001650	fibrillar center
0.42	GO:0015630	microtubule cytoskeleton

sp|Q86XN7|PRSR1_HUMAN
Proline and serine-rich protein 1
Search

PROSER1

0.97	LOW QUALITY PROTEIN: proline and serine-rich protein 1

sp|Q86XN8|MEX3D_HUMAN
RNA-binding protein MEX3D
Search

MEX3D

0.80	Mex-3 RNA binding family member D

0.42	GO:0003415	chondrocyte hypertrophy
0.41	GO:0097009	energy homeostasis
0.40	GO:0045598	regulation of fat cell differentiation

0.59

GO:0003723

RNA binding

0.52	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.42	GO:0005829	cytosol
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part

sp|Q86XP0|PA24D_HUMAN
Cytosolic phospholipase A2 delta
Search

0.66	Cytosolic phospholipase A2 epsilon

0.80	GO:0009395	phospholipid catabolic process
0.57	GO:0046503	glycerolipid catabolic process
0.51	GO:0006650	glycerophospholipid metabolic process
0.37	GO:0097164	ammonium ion metabolic process
0.36	GO:0006575	cellular modified amino acid metabolic process
0.36	GO:0045017	glycerolipid biosynthetic process
0.35	GO:0008654	phospholipid biosynthetic process
0.34	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0007567	parturition
0.34	GO:0019369	arachidonic acid metabolic process

0.83	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.83	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.80	GO:0004623	phospholipase A2 activity
0.53	GO:0046872	metal ion binding
0.40	GO:0004622	lysophospholipase activity
0.39	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.34	GO:0005544	calcium-dependent phospholipid binding

0.48	GO:0005737	cytoplasm
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0097708	intracellular vesicle
0.34	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0012506	vesicle membrane
0.33	GO:0012505	endomembrane system
0.33	GO:0005576	extracellular region
0.32	GO:0031975	envelope

0.80

EC:3.1.1.4

GO:0004623

sp|Q86XP1|DGKH_HUMAN
Diacylglycerol kinase eta
Search

DGKH

0.48	Diacylglycerol kinase eta

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.53	GO:0046473	phosphatidic acid metabolic process
0.51	GO:0051259	protein oligomerization
0.39	GO:0010033	response to organic substance
0.38	GO:0046339	diacylglycerol metabolic process
0.35	GO:0030168	platelet activation
0.32	GO:0006508	proteolysis

0.80	GO:0004143	diacylglycerol kinase activity
0.75	GO:0003951	NAD+ kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.33	GO:0046872	metal ion binding
0.32	GO:0004252	serine-type endopeptidase activity

0.50	GO:0005768	endosome
0.38	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.80	EC:2.7.1.107	GO:0004143
0.75	KEGG:R00104	GO:0003951

sp|Q86XP3|DDX42_HUMAN
ATP-dependent RNA helicase DDX42
Search

DDX42

0.96	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

0.63	GO:0042981	regulation of apoptotic process
0.56	GO:0008104	protein localization
0.53	GO:0010501	RNA secondary structure unwinding

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004386	helicase activity
0.51	GO:0003676	nucleic acid binding
0.50	GO:0008186	RNA-dependent ATPase activity
0.44	GO:0140098	catalytic activity, acting on RNA

0.67	GO:0016607	nuclear speck
0.58	GO:0005829	cytosol
0.49	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|Q86XP6|GKN2_HUMAN
Gastrokine-2
Search

GKN2

0.97	Gastrokine-2

0.58

GO:0042127

regulation of cell proliferation

0.85	GO:0045178	basal part of cell
0.56	GO:0005615	extracellular space
0.38	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

sp|Q86XQ3|CTSR3_HUMAN
Cation channel sperm-associated protein 3
Search

CATSPER3

0.97	Cation channel sperm-associated protein 3 transcript variant 1

0.72	GO:0048240	sperm capacitation
0.70	GO:0006816	calcium ion transport
0.70	GO:0030317	flagellated sperm motility
0.60	GO:0006814	sodium ion transport
0.60	GO:0034220	ion transmembrane transport
0.57	GO:0086010	membrane depolarization during action potential
0.40	GO:0034765	regulation of ion transmembrane transport
0.40	GO:0032570	response to progesterone
0.40	GO:0035036	sperm-egg recognition
0.39	GO:0071804	cellular potassium ion transport

0.74	GO:0005245	voltage-gated calcium channel activity
0.40	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0005515	protein binding

0.74	GO:0005891	voltage-gated calcium channel complex
0.69	GO:0001669	acrosomal vesicle
0.59	GO:0005783	endoplasmic reticulum
0.41	GO:0031514	motile cilium
0.40	GO:0008076	voltage-gated potassium channel complex

sp|Q86XR2|NIBL2_HUMAN
Niban-like protein 2
Search

FAM129C

0.97	Niban-like protein 2

sp|Q86XR5|PRIMA_HUMAN
Proline-rich membrane anchor 1
Search

PRIMA1

0.97	Proline rich membrane anchor 1

0.39	GO:0042135	neurotransmitter catabolic process
0.36	GO:0051649	establishment of localization in cell
0.33	GO:0006508	proteolysis
0.32	GO:0007015	actin filament organization
0.32	GO:0016192	vesicle-mediated transport
0.32	GO:0007049	cell cycle

0.39	GO:0043495	protein membrane anchor
0.37	GO:0019899	enzyme binding
0.32	GO:0003779	actin binding
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0003677	DNA binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0045202	synapse
0.39	GO:0030054	cell junction
0.36	GO:0031226	intrinsic component of plasma membrane
0.33	GO:0005576	extracellular region
0.33	GO:0005802	trans-Golgi network
0.32	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

0.32

GO:0004222

sp|Q86XR7|TCAM2_HUMAN
TIR domain-containing adapter molecule 2
Search

TICAM2

0.97	TIR domain-containing adapter molecule 2

0.70	GO:2000494	positive regulation of interleukin-18-mediated signaling pathway
0.68	GO:0035669	TRAM-dependent toll-like receptor 4 signaling pathway
0.66	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.66	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
0.66	GO:0070671	response to interleukin-12
0.63	GO:0032729	positive regulation of interferon-gamma production
0.62	GO:0032755	positive regulation of interleukin-6 production
0.62	GO:0071222	cellular response to lipopolysaccharide
0.57	GO:0051607	defense response to virus
0.45	GO:0071650	negative regulation of chemokine (C-C motif) ligand 5 production

0.56	GO:0005543	phospholipid binding
0.37	GO:0004871	signal transducer activity
0.37	GO:0005149	interleukin-1 receptor binding
0.36	GO:0046982	protein heterodimerization activity

0.56	GO:0005768	endosome
0.45	GO:0005886	plasma membrane
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005794	Golgi apparatus
0.38	GO:0030667	secretory granule membrane
0.36	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

sp|Q86XR8|CEP57_HUMAN
Centrosomal protein of 57 kDa
Search

CEP57

0.87	Centrosomal protein of isoform A

0.83	GO:0034453	microtubule anchoring
0.60	GO:0000060	protein import into nucleus, translocation
0.59	GO:0008543	fibroblast growth factor receptor signaling pathway
0.57	GO:0007286	spermatid development
0.55	GO:0051260	protein homooligomerization
0.48	GO:0000070	mitotic sister chromatid segregation
0.37	GO:0097711	ciliary basal body-plasma membrane docking
0.36	GO:0000086	G2/M transition of mitotic cell cycle
0.36	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.80	GO:0043015	gamma-tubulin binding
0.72	GO:0042802	identical protein binding
0.72	GO:0008017	microtubule binding
0.61	GO:0017134	fibroblast growth factor binding
0.51	GO:0046983	protein dimerization activity

0.57	GO:0005813	centrosome
0.54	GO:0005874	microtubule
0.52	GO:0005794	Golgi apparatus
0.46	GO:0005634	nucleus
0.35	GO:0005829	cytosol

sp|Q86XS5|ANGL5_HUMAN
Angiopoietin-related protein 5
Search

ANGPTL5

0.97	Angiopoietin like 5

0.50	GO:0032501	multicellular organismal process
0.48	GO:0007599	hemostasis
0.48	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.48	GO:0042060	wound healing
0.47	GO:0001775	cell activation
0.47	GO:0051258	protein polymerization
0.46	GO:0009653	anatomical structure morphogenesis
0.45	GO:0043066	negative regulation of apoptotic process
0.44	GO:0010519	negative regulation of phospholipase activity
0.44	GO:0051005	negative regulation of lipoprotein lipase activity

0.58	GO:0005515	protein binding
0.48	GO:0060090	molecular adaptor activity
0.44	GO:0005044	scavenger receptor activity
0.43	GO:0004859	phospholipase inhibitor activity
0.41	GO:0030545	receptor regulator activity
0.40	GO:0044877	macromolecular complex binding
0.34	GO:0003676	nucleic acid binding

0.63	GO:0005576	extracellular region
0.42	GO:0005769	early endosome
0.41	GO:0009986	cell surface
0.40	GO:0043234	protein complex
0.40	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|Q86XS8|GOLI_HUMAN
E3 ubiquitin-protein ligase RNF130
Search

RNF130

0.91	Ring finger protein 130

0.50	GO:0012501	programmed cell death
0.48	GO:0016567	protein ubiquitination
0.35	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.35	GO:0038084	vascular endothelial growth factor signaling pathway
0.34	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0065009	regulation of molecular function

0.49	GO:0004842	ubiquitin-protein transferase activity
0.49	GO:0016874	ligase activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0003924	GTPase activity

0.38	GO:0005737	cytoplasm
0.33	GO:0005887	integral component of plasma membrane

0.49	EC:6	GO:0016874
0.49	KEGG:R03876	GO:0004842

sp|Q86XT2|VP37D_HUMAN
Vacuolar protein sorting-associated protein 37D
Search

VPS37D

0.97	VPS37D, ESCRT-I subunit

0.82	GO:0032509	endosome transport via multivesicular body sorting pathway
0.65	GO:0015031	protein transport

0.83

GO:0000813

ESCRT I complex

sp|Q86XT4|TRI50_HUMAN
E3 ubiquitin-protein ligase TRIM50
Search

TRIM50

0.97	Tripartite motif containing 50

0.55	GO:0070201	regulation of establishment of protein localization
0.40	GO:0061930	regulation of erythrocyte enucleation
0.40	GO:1902838	regulation of nuclear migration along microtubule
0.39	GO:0016567	protein ubiquitination
0.39	GO:1903431	positive regulation of cell maturation
0.39	GO:0045648	positive regulation of erythrocyte differentiation
0.38	GO:0035372	protein localization to microtubule
0.37	GO:0051130	positive regulation of cellular component organization
0.37	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0032874	positive regulation of stress-activated MAPK cascade

0.61	GO:0008270	zinc ion binding
0.46	GO:0016874	ligase activity
0.41	GO:0042802	identical protein binding
0.40	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0045504	dynein heavy chain binding
0.39	GO:0045505	dynein intermediate chain binding
0.37	GO:0061659	ubiquitin-like protein ligase activity
0.37	GO:0051219	phosphoprotein binding
0.36	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0008017	microtubule binding

0.59	GO:0016235	aggresome
0.40	GO:0005829	cytosol
0.36	GO:0005881	cytoplasmic microtubule
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.32	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

0.46	EC:6	GO:0016874
0.40	KEGG:R03876	GO:0004842

sp|Q86XT9|TM219_HUMAN
Insulin-like growth factor-binding protein 3 receptor
Search

TMEM219

0.91	Insulin-like growth factor-binding protein 3 receptor

0.51	GO:0006915	apoptotic process
0.42	GO:0042981	regulation of apoptotic process

0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q86XU0|ZN677_HUMAN
Zinc finger protein 677
Search

0.64	Zinc finger protein 546

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.39	GO:0060669	embryonic placenta morphogenesis
0.38	GO:0006351	transcription, DNA-templated
0.36	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|Q86XW9|TXND6_HUMAN
Thioredoxin domain-containing protein 6
Search

NME9

0.26	LOW QUALITY PROTEIN: thioredoxin domain-containing protein 6

0.75	GO:0006228	UTP biosynthetic process
0.75	GO:0006183	GTP biosynthetic process
0.71	GO:0046036	CTP metabolic process
0.67	GO:0006165	nucleoside diphosphate phosphorylation
0.66	GO:0045454	cell redox homeostasis
0.35	GO:0030317	flagellated sperm motility
0.35	GO:0060271	cilium assembly
0.34	GO:0034614	cellular response to reactive oxygen species
0.33	GO:0007155	cell adhesion
0.32	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.75	GO:0004550	nucleoside diphosphate kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008017	microtubule binding
0.34	GO:0046872	metal ion binding
0.33	GO:0030246	carbohydrate binding
0.32	GO:0004519	endonuclease activity

0.36	GO:0097598	sperm cytoplasmic droplet
0.36	GO:0005856	cytoskeleton
0.36	GO:0097228	sperm principal piece
0.35	GO:0097014	ciliary plasm
0.33	GO:1902494	catalytic complex
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.75

EC:2.7.4.6

GO:0004550

sp|Q86XX4|FRAS1_HUMAN
Extracellular matrix protein FRAS1
Search

FRAS1

0.93	Fraser extracellular matrix complex subunit 1

0.74	GO:0003338	metanephros morphogenesis
0.72	GO:0060021	palate development
0.71	GO:0030326	embryonic limb morphogenesis
0.70	GO:0043588	skin development
0.67	GO:0002009	morphogenesis of an epithelium
0.60	GO:0007154	cell communication
0.56	GO:0015031	protein transport
0.40	GO:0033334	fin morphogenesis
0.40	GO:0071711	basement membrane organization
0.40	GO:0010669	epithelial structure maintenance

0.81	GO:0005604	basement membrane
0.30	GO:0044425	membrane part

sp|Q86XZ4|SPAS2_HUMAN
Spermatogenesis-associated serine-rich protein 2
Search

SPATS2

0.97	LOW QUALITY PROTEIN: spermatogenesis-associated serine-rich protein 2

0.38	GO:0023014	signal transduction by protein phosphorylation
0.37	GO:0000160	phosphorelay signal transduction system
0.34	GO:0034765	regulation of ion transmembrane transport
0.34	GO:0071805	potassium ion transmembrane transport

0.39	GO:0003723	RNA binding
0.38	GO:0000155	phosphorelay sensor kinase activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.67	GO:0005829	cytosol
0.46	GO:0005730	nucleolus
0.40	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.38

EC:2.7.3

GO:0000155

sp|Q86Y01|DTX1_HUMAN
E3 ubiquitin-protein ligase DTX1
Search

0.97	Deltex E3 ubiquitin ligase 1

0.54	GO:0045581	negative regulation of T cell differentiation
0.53	GO:0008593	regulation of Notch signaling pathway
0.53	GO:0045665	negative regulation of neuron differentiation
0.53	GO:0007219	Notch signaling pathway
0.52	GO:1990823	response to leukemia inhibitory factor
0.52	GO:0010001	glial cell differentiation
0.50	GO:0071345	cellular response to cytokine stimulus
0.39	GO:0016567	protein ubiquitination
0.35	GO:0006366	transcription by RNA polymerase II
0.35	GO:0032479	regulation of type I interferon production

0.61	GO:0008270	zinc ion binding
0.54	GO:0005112	Notch binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0016874	ligase activity
0.37	GO:0017124	SH3 domain binding
0.35	GO:0003713	transcription coactivator activity
0.34	GO:0016740	transferase activity
0.33	GO:0140096	catalytic activity, acting on a protein

0.50	GO:0016604	nuclear body
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0016874

sp|Q86Y07|VRK2_HUMAN
Serine/threonine-protein kinase VRK2
Search

VRK2

0.93	Vaccinia related kinase

0.70	GO:2000659	regulation of interleukin-1-mediated signaling pathway
0.64	GO:0046777	protein autophosphorylation
0.60	GO:0043408	regulation of MAPK cascade
0.58	GO:0034599	cellular response to oxidative stress
0.54	GO:0018105	peptidyl-serine phosphorylation
0.47	GO:0008360	regulation of cell shape
0.41	GO:0072355	histone H3-T3 phosphorylation
0.41	GO:0090166	Golgi disassembly

0.64	GO:0004672	protein kinase activity
0.61	GO:0019901	protein kinase binding
0.59	GO:0019904	protein domain specific binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0031493	nucleosomal histone binding

0.56	GO:0005789	endoplasmic reticulum membrane
0.53	GO:0005634	nucleus
0.50	GO:0031966	mitochondrial membrane
0.49	GO:0043234	protein complex
0.39	GO:0005795	Golgi stack
0.37	GO:0005829	cytosol
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q86Y13|DZIP3_HUMAN
E3 ubiquitin-protein ligase DZIP3
Search

DZIP3

0.90	DAZ interacting zinc finger protein 3

0.82	GO:0000209	protein polyubiquitination
0.57	GO:0030968	endoplasmic reticulum unfolded protein response
0.56	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.56	GO:0030433	ubiquitin-dependent ERAD pathway

0.76	GO:0061630	ubiquitin protein ligase activity
0.74	GO:0031593	polyubiquitin modification-dependent protein binding
0.72	GO:0019902	phosphatase binding
0.60	GO:1990381	ubiquitin-specific protease binding
0.59	GO:0003723	RNA binding
0.51	GO:0051082	unfolded protein binding
0.37	GO:0016874	ligase activity
0.34	GO:0008270	zinc ion binding

0.60	GO:0044322	endoplasmic reticulum quality control compartment
0.59	GO:0036513	Derlin-1 retrotranslocation complex
0.58	GO:0000836	Hrd1p ubiquitin ligase complex
0.30	GO:0016021	integral component of membrane

0.37

GO:0016874

sp|Q86Y22|CONA1_HUMAN
Collagen alpha-1(XXIII) chain
Search

COL23A1

0.95	Collagen type XXIII alpha 1 chain

0.46	GO:0060385	axonogenesis involved in innervation
0.39	GO:0070207	protein homotrimerization
0.35	GO:0030574	collagen catabolic process

0.46	GO:0008201	heparin binding
0.45	GO:0001540	amyloid-beta binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0008483	transaminase activity
0.35	GO:0030170	pyridoxal phosphate binding
0.35	GO:0005201	extracellular matrix structural constituent

0.73	GO:0005581	collagen trimer
0.43	GO:0005615	extracellular space
0.40	GO:0005887	integral component of plasma membrane
0.37	GO:0009986	cell surface
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005604	basement membrane

0.35

EC:2.6.1

GO:0008483

sp|Q86Y25|Z354C_HUMAN
Zinc finger protein 354C
Search

ZNF879

0.42	Zinc finger and SCAN domain containing 2

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.43	GO:0006351	transcription, DNA-templated
0.34	GO:0007219	Notch signaling pathway
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.49	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003682	chromatin binding
0.33	GO:0004930	G-protein coupled receptor activity

0.47	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.39	GO:0012505	endomembrane system
0.38	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.34	GO:0031974	membrane-enclosed lumen
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q86Y26|NUTM1_HUMAN
NUT family member 1
Search

NUTM1

0.97	NUT midline carcinoma family member 1

0.57

GO:0005515

protein binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm

sp|Q86Y27|BAGE5_HUMAN
B melanoma antigen 5
Search

0.94	B melanoma antigen 5

0.66

GO:0005576

extracellular region

sp|Q86Y28|BAGE4_HUMAN
B melanoma antigen 4
Search

0.94	B melanoma antigen 4

0.66

GO:0005576

extracellular region

sp|Q86Y29|BAGE3_HUMAN
B melanoma antigen 3
Search

0.89	B melanoma antigen 3

0.66

GO:0005576

extracellular region

sp|Q86Y30|BAGE2_HUMAN
B melanoma antigen 2
Search

0.89	B melanoma antigen 2

0.66

GO:0005576

extracellular region

sp|Q86Y33|CD20B_HUMAN
Cell division cycle protein 20 homolog B
Search

CDC20B

0.94	Cell division cycle protein 20 like protein B

0.83	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.68	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.54	GO:0051301	cell division
0.50	GO:0031915	positive regulation of synaptic plasticity
0.50	GO:0090129	positive regulation of synapse maturation
0.48	GO:0000070	mitotic sister chromatid segregation
0.47	GO:0040020	regulation of meiotic nuclear division
0.47	GO:0090307	mitotic spindle assembly
0.45	GO:0007062	sister chromatid cohesion
0.38	GO:0070727	cellular macromolecule localization

0.84	GO:0097027	ubiquitin-protein transferase activator activity
0.84	GO:0010997	anaphase-promoting complex binding
0.48	GO:0008022	protein C-terminus binding
0.44	GO:0019899	enzyme binding
0.36	GO:0004896	cytokine receptor activity
0.34	GO:0009922	fatty acid elongase activity

0.48	GO:0005680	anaphase-promoting complex
0.44	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.42	GO:0033597	mitotic checkpoint complex
0.36	GO:0000922	spindle pole
0.36	GO:0005815	microtubule organizing center
0.36	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0034399	nuclear periphery
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|Q86Y34|AGRG3_HUMAN
Adhesion G protein-coupled receptor G3
Search

ADGRG3

0.91	Adhesion G protein-coupled receptor G3

0.67	GO:0007166	cell surface receptor signaling pathway
0.67	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0032792	negative regulation of CREB transcription factor activity
0.66	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.62	GO:0030183	B cell differentiation
0.59	GO:0030334	regulation of cell migration
0.39	GO:0043312	neutrophil degranulation
0.34	GO:0060347	heart trabecula formation
0.34	GO:0022011	myelination in peripheral nervous system
0.34	GO:0019933	cAMP-mediated signaling

0.68	GO:0004930	G-protein coupled receptor activity
0.34	GO:0043236	laminin binding

0.48	GO:0005886	plasma membrane
0.44	GO:0005829	cytosol
0.39	GO:0035579	specific granule membrane
0.36	GO:0045177	apical part of cell
0.35	GO:0070062	extracellular exosome
0.35	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

sp|Q86Y37|CACL1_HUMAN
CDK2-associated and cullin domain-containing protein 1
Search

CACUL1

0.97	CDK2-associated and cullin domain-containing protein 1

0.71	GO:0006511	ubiquitin-dependent protein catabolic process
0.61	GO:0000082	G1/S transition of mitotic cell cycle
0.59	GO:0008284	positive regulation of cell proliferation
0.58	GO:0045860	positive regulation of protein kinase activity
0.46	GO:0016567	protein ubiquitination

0.77	GO:0031625	ubiquitin protein ligase binding
0.58	GO:0019901	protein kinase binding
0.48	GO:0061630	ubiquitin protein ligase activity

0.48

GO:0031461

cullin-RING ubiquitin ligase complex

sp|Q86Y38|XYLT1_HUMAN
Xylosyltransferase 1
Search

XYLT1

0.91	Xylosyltransferase I

0.68	GO:0006024	glycosaminoglycan biosynthetic process
0.47	GO:0030166	proteoglycan biosynthetic process
0.45	GO:0030201	heparan sulfate proteoglycan metabolic process
0.45	GO:0050654	chondroitin sulfate proteoglycan metabolic process
0.45	GO:1903510	mucopolysaccharide metabolic process
0.40	GO:0044272	sulfur compound biosynthetic process
0.39	GO:0048701	embryonic cranial skeleton morphogenesis
0.37	GO:0043436	oxoacid metabolic process
0.37	GO:0034605	cellular response to heat
0.35	GO:0048681	negative regulation of axon regeneration

0.85	GO:0030158	protein xylosyltransferase activity
0.75	GO:0008375	acetylglucosaminyltransferase activity

0.48	GO:0000139	Golgi membrane
0.40	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.2.26

GO:0030158

sp|Q86Y39|NDUAB_HUMAN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Search

NDUFA11

0.40	NADH dehydrogenase

0.50	GO:0032981	mitochondrial respiratory chain complex I assembly
0.38	GO:0055114	oxidation-reduction process
0.35	GO:0006119	oxidative phosphorylation
0.33	GO:0055085	transmembrane transport

0.33

GO:0022857

transmembrane transporter activity

0.56	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0016021	integral component of membrane

sp|Q86Y46|K2C73_HUMAN
Keratin, type II cytoskeletal 73
Search

0.96	Keratin, type II cytoskeletal 73

0.56	GO:0045104	intermediate filament cytoskeleton organization
0.51	GO:0031069	hair follicle morphogenesis
0.46	GO:0097435	supramolecular fiber organization
0.40	GO:0030855	epithelial cell differentiation
0.38	GO:0012501	programmed cell death
0.36	GO:0050680	negative regulation of epithelial cell proliferation

0.62	GO:0005198	structural molecule activity
0.48	GO:1990254	keratin filament binding

0.83	GO:0045095	keratin filament
0.41	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.35	GO:0009986	cell surface
0.34	GO:0005634	nucleus

sp|Q86Y56|DAAF5_HUMAN
Dynein assembly factor 5, axonemal
Search

DNAAF5

0.94	Dynein axonemal assembly factor 5

0.86	GO:0036158	outer dynein arm assembly
0.85	GO:0036159	inner dynein arm assembly
0.83	GO:0003341	cilium movement

0.85

GO:0045505

dynein intermediate chain binding

0.49	GO:0005737	cytoplasm
0.49	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q86Y78|LYPD6_HUMAN
Ly6/PLAUR domain-containing protein 6
Search

LYPD6

0.97	Ly6/PLAUR domain-containing protein 6

0.78	GO:0099601	regulation of neurotransmitter receptor activity
0.73	GO:2000272	negative regulation of receptor activity
0.55	GO:0060827	regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
0.53	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
0.53	GO:0060061	Spemann organizer formation
0.50	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.35	GO:0006501	C-terminal protein lipidation
0.32	GO:0006508	proteolysis

0.81	GO:0030548	acetylcholine receptor regulator activity
0.73	GO:0030547	receptor inhibitor activity
0.36	GO:0005515	protein binding
0.34	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0031225	anchored component of membrane
0.44	GO:0031226	intrinsic component of plasma membrane
0.43	GO:0045121	membrane raft
0.41	GO:0043005	neuron projection
0.41	GO:0045202	synapse
0.41	GO:0030054	cell junction
0.39	GO:0005576	extracellular region
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q86Y79|PTH_HUMAN
Probable peptidyl-tRNA hydrolase
Search

PTRH1

0.47	Peptidyl-tRNA hydrolase

0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process
0.32	GO:0032259	methylation
0.32	GO:0036211	protein modification process

0.79	GO:0004045	aminoacyl-tRNA hydrolase activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0140096	catalytic activity, acting on a protein

0.47

GO:0005739

mitochondrion

0.79

EC:3.1.1.29

GO:0004045

sp|Q86Y82|STX12_HUMAN
Syntaxin-12
Search

STX12

0.91	Protein phosphatase 1 regulatory subunit 8

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.56	GO:0033344	cholesterol efflux
0.54	GO:0000045	autophagosome assembly
0.52	GO:0050821	protein stabilization
0.47	GO:0048284	organelle fusion
0.47	GO:0016050	vesicle organization
0.47	GO:0140056	organelle localization by membrane tethering
0.40	GO:1902685	positive regulation of receptor localization to synapse

0.80	GO:0005484	SNAP receptor activity
0.49	GO:0000149	SNARE binding
0.39	GO:0019869	chloride channel inhibitor activity

0.56	GO:0031201	SNARE complex
0.55	GO:0031083	BLOC-1 complex
0.54	GO:0030139	endocytic vesicle
0.54	GO:0000407	phagophore assembly site
0.53	GO:0045121	membrane raft
0.44	GO:0012505	endomembrane system
0.39	GO:0005766	primary lysosome
0.39	GO:0001772	immunological synapse
0.39	GO:0099503	secretory vesicle
0.38	GO:0044433	cytoplasmic vesicle part

sp|Q86Y91|KI18B_HUMAN
Kinesin-like protein KIF18B
Search

0.18	Kinesin family member 18B

0.74

GO:0007018

microtubule-based movement

0.75	GO:0003777	microtubule motor activity
0.70	GO:0008017	microtubule binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:1990752	microtubule end
0.63	GO:0016604	nuclear body
0.57	GO:0005829	cytosol

sp|Q86Y97|KMT5C_HUMAN
Histone-lysine N-methyltransferase KMT5C
Search

KMT5C

0.45	Histone-lysine N-methyltransferase

0.85	GO:0034773	histone H4-K20 trimethylation
0.42	GO:0040014	regulation of multicellular organism growth
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0007517	muscle organ development
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.85	GO:0042799	histone methyltransferase activity (H4-K20 specific)
0.34	GO:0005515	protein binding

0.56	GO:0005721	pericentric heterochromatin
0.56	GO:0000780	condensed nuclear chromosome, centromeric region
0.56	GO:0005720	nuclear heterochromatin
0.49	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q86YA3|ZGRF1_HUMAN
Protein ZGRF1
Search

ZGRF1

0.92	Zinc finger GRF-type containing 1

0.63

GO:0008270

zinc ion binding

sp|Q86YB7|ECHD2_HUMAN
Enoyl-CoA hydratase domain-containing protein 2, mitochondrial
Search

ECHDC2

0.95	Enoyl-CoA hydratase domain-containing protein 2

0.45	GO:0006635	fatty acid beta-oxidation
0.36	GO:0006574	valine catabolic process

0.46	GO:0004300	enoyl-CoA hydratase activity
0.36	GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity
0.33	GO:0003859	3-hydroxybutyryl-CoA dehydratase activity
0.33	GO:0016853	isomerase activity

0.40	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.46	EC:4.2.1.17	GO:0004300
0.33	KEGG:R03027	GO:0003859

sp|Q86YB8|ERO1B_HUMAN
ERO1-like protein beta
Search

ERO1B

0.50	Endoplasmic reticulum oxidoreductase 1 beta

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0022417	protein maturation by protein folding
0.51	GO:0019471	4-hydroxyproline metabolic process
0.50	GO:0030070	insulin processing
0.48	GO:0034975	protein folding in endoplasmic reticulum
0.47	GO:0030198	extracellular matrix organization
0.47	GO:0042593	glucose homeostasis
0.43	GO:0045454	cell redox homeostasis
0.40	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process

0.83	GO:0003756	protein disulfide isomerase activity
0.76	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.47	GO:0015035	protein disulfide oxidoreductase activity
0.34	GO:0051082	unfolded protein binding

0.70	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.83

EC:5.3.4.1

GO:0003756

sp|Q86YC2|PALB2_HUMAN
Partner and localizer of BRCA2
Search

PALB2

0.93	Partner and localizer of BRCA2

0.87	GO:0001833	inner cell mass cell proliferation
0.86	GO:0036342	post-anal tail morphogenesis
0.85	GO:0001756	somitogenesis
0.85	GO:0035264	multicellular organism growth
0.84	GO:0007498	mesoderm development
0.80	GO:0048568	embryonic organ development
0.78	GO:0043066	negative regulation of apoptotic process
0.77	GO:0009887	animal organ morphogenesis
0.77	GO:0000724	double-strand break repair via homologous recombination
0.48	GO:0000732	strand displacement

0.55	GO:0003677	DNA binding
0.39	GO:0005515	protein binding

0.70

GO:0005654

nucleoplasm

sp|Q86YC3|NRROS_HUMAN
Negative regulator of reactive oxygen species
Search

NRROS

0.97	Negative regulator of reactive oxygen species

0.59	GO:0006954	inflammatory response
0.57	GO:0006955	immune response
0.56	GO:0006801	superoxide metabolic process
0.36	GO:0030433	ubiquitin-dependent ERAD pathway
0.34	GO:0006468	protein phosphorylation
0.32	GO:0051014	actin filament severing
0.32	GO:0007411	axon guidance
0.32	GO:0006915	apoptotic process
0.32	GO:0030036	actin cytoskeleton organization
0.32	GO:0006470	protein dephosphorylation

0.34	GO:0004672	protein kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004721	phosphoprotein phosphatase activity
0.32	GO:0003856	3-dehydroquinate synthase activity
0.31	GO:0044877	macromolecular complex binding
0.31	GO:0016491	oxidoreductase activity
0.31	GO:0043169	cation binding

0.54	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.32	EC:3.1.3.16	GO:0004721
0.32	KEGG:R03083	GO:0003856

sp|Q86YD1|PTOV1_HUMAN
Prostate tumor-overexpressed gene 1 protein
Search

PTOV1

0.70	Prostate tumor overexpressed 1

0.30	GO:0051252	regulation of RNA metabolic process
0.30	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.30	GO:0090304	nucleic acid metabolic process
0.30	GO:0019438	aromatic compound biosynthetic process
0.30	GO:0044260	cellular macromolecule metabolic process
0.30	GO:0010467	gene expression
0.30	GO:0018130	heterocycle biosynthetic process
0.30	GO:1901576	organic substance biosynthetic process
0.30	GO:0010468	regulation of gene expression
0.30	GO:0044271	cellular nitrogen compound biosynthetic process

0.61	GO:0005634	nucleus
0.30	GO:0071944	cell periphery
0.30	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q86YD3|TMM25_HUMAN
Transmembrane protein 25
Search

TMEM25

0.97	LOW QUALITY PROTEIN: transmembrane protein 25

0.34

GO:0005515

protein binding

0.37	GO:0005576	extracellular region
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q86YD5|LRAD3_HUMAN
Low-density lipoprotein receptor class A domain-containing protein 3
Search

LDLRAD3

0.97	Low-density lipoprotein receptor class A domain-containing protein 3

0.59	GO:0070613	regulation of protein processing
0.52	GO:0006898	receptor-mediated endocytosis

0.60	GO:0001540	amyloid-beta binding
0.35	GO:0005509	calcium ion binding

0.44	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q86YD7|F90A1_HUMAN
Protein FAM90A1
Search

0.45	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0000128	flocculation

0.60	GO:0005515	protein binding
0.49	GO:0016503	pheromone receptor activity

0.30

GO:0044425

membrane part

sp|Q86YE8|ZN573_HUMAN
Zinc finger protein 573
Search

0.67	Zinc finger protein 28

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0007275	multicellular organism development
0.34	GO:1902680	positive regulation of RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q86YF9|DZIP1_HUMAN
Zinc finger protein DZIP1
Search

DZIP1

0.89	DAZ interacting zinc finger protein 1

0.75	GO:0051220	cytoplasmic sequestering of protein
0.72	GO:0007224	smoothened signaling pathway
0.71	GO:0060271	cilium assembly
0.57	GO:0045184	establishment of protein localization
0.36	GO:0032880	regulation of protein localization

0.51

GO:0003676

nucleic acid binding

0.75	GO:0097539	ciliary transition fiber
0.73	GO:0036064	ciliary basal body
0.72	GO:0005814	centriole
0.61	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol

sp|Q86YG4|NT5D4_HUMAN
5'-nucleotidase domain-containing protein 4
Search

NT5C2

0.87	Cytosolic purine 5'-nucleotidase

0.46	GO:0046085	adenosine metabolic process
0.44	GO:0016311	dephosphorylation
0.41	GO:0046040	IMP metabolic process
0.38	GO:0071466	cellular response to xenobiotic stimulus
0.34	GO:0006195	purine nucleotide catabolic process
0.32	GO:0016310	phosphorylation

0.53	GO:0046872	metal ion binding
0.48	GO:0008253	5'-nucleotidase activity
0.35	GO:0050146	nucleoside phosphotransferase activity
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0036094	small molecule binding

0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.48

EC:3.1.3.5

GO:0008253

sp|Q86YH2|Z280B_HUMAN
Zinc finger protein 280B
Search

0.90	Suppressor of hairy wing homolog 2

0.35	GO:0097659	nucleic acid-templated transcription
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding

0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q86YH6|DLP1_HUMAN
Decaprenyl-diphosphate synthase subunit 2
Search

PDSS2

0.95	Mutant decaprenyl diphosphate synthase subunit 2

0.70	GO:0008299	isoprenoid biosynthetic process
0.60	GO:0051290	protein heterotetramerization
0.56	GO:0050878	regulation of body fluid levels
0.54	GO:0006744	ubiquinone biosynthetic process

0.63	GO:0000010	trans-hexaprenyltranstransferase activity
0.62	GO:0050347	trans-octaprenyltranstransferase activity
0.53	GO:0046982	protein heterodimerization activity

0.50	GO:1990234	transferase complex
0.50	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.62	EC:2.5.1.84 EC:2.5.1.85	GO:0050347
0.63	KEGG:R05612	GO:0000010

sp|Q86YI8|PHF13_HUMAN
PHD finger protein 13
Search

PHF13

0.96	PHD finger protein 13

0.60	GO:0007076	mitotic chromosome condensation
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0051301	cell division
0.36	GO:1901097	negative regulation of autophagosome maturation
0.36	GO:1902902	negative regulation of autophagosome assembly
0.35	GO:0006914	autophagy
0.35	GO:0031398	positive regulation of protein ubiquitination

0.57	GO:0003682	chromatin binding
0.53	GO:0046872	metal ion binding
0.36	GO:0140034	methylation-dependent protein binding
0.36	GO:0042393	histone binding
0.32	GO:0003677	DNA binding

0.48	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm

sp|Q86YJ5|MARH9_HUMAN
E3 ubiquitin-protein ligase MARCH9
Search

MARCH9

0.53	Membrane-associated RING-CH protein IX

0.47

GO:0016567

protein ubiquitination

0.63	GO:0008270	zinc ion binding
0.50	GO:0016874	ligase activity
0.47	GO:0004842	ubiquitin-protein transferase activity

0.57	GO:0005802	trans-Golgi network
0.57	GO:0005795	Golgi stack
0.38	GO:0000139	Golgi membrane
0.37	GO:0005765	lysosomal membrane
0.30	GO:0044425	membrane part

0.50	EC:6	GO:0016874
0.47	KEGG:R03876	GO:0004842

sp|Q86YJ6|THNS2_HUMAN
Threonine synthase-like 2
Search

THNSL2

0.97	Threonine synthase like 2

0.86	GO:0046360	2-oxobutyrate biosynthetic process
0.72	GO:0009071	serine family amino acid catabolic process
0.66	GO:0016311	dephosphorylation
0.57	GO:0009088	threonine biosynthetic process
0.39	GO:0010469	regulation of receptor activity
0.38	GO:0008345	larval locomotory behavior
0.37	GO:0007420	brain development

0.86	GO:0070905	serine binding
0.65	GO:0070279	vitamin B6 binding
0.62	GO:0004795	threonine synthase activity
0.58	GO:0050662	coenzyme binding
0.40	GO:0005125	cytokine activity

0.38

GO:0005615

extracellular space

0.62

EC:4.2.3.1

GO:0004795

sp|Q86YJ7|AN13B_HUMAN
Ankyrin repeat domain-containing protein 13B
Search

ANKRD13B

0.92	LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 13B

0.39	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation

0.40	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.38	GO:0004725	protein tyrosine phosphatase activity

0.53	GO:0043231	intracellular membrane-bounded organelle
0.43	GO:0005770	late endosome
0.43	GO:0005769	early endosome
0.37	GO:0005886	plasma membrane
0.37	GO:0031461	cullin-RING ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:3.1.3

GO:0008138

sp|Q86YL5|TDRP_HUMAN
Testis development-related protein
Search

TDRP

0.97	Testis development-related protein variant B

0.80

GO:0007283

spermatogenesis

0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus

sp|Q86YL7|PDPN_HUMAN
Podoplanin
Search

PDPN

0.97	Podoplanin

0.65	GO:1901731	positive regulation of platelet aggregation
0.65	GO:1905863	invadopodium organization
0.61	GO:0090091	positive regulation of extracellular matrix disassembly
0.61	GO:2000392	regulation of lamellipodium morphogenesis
0.59	GO:0090505	epiboly involved in wound healing
0.59	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.58	GO:0007266	Rho protein signal transduction
0.57	GO:0051272	positive regulation of cellular component movement
0.55	GO:0040017	positive regulation of locomotion
0.55	GO:0030334	regulation of cell migration

0.58	GO:0019956	chemokine binding
0.53	GO:0051087	chaperone binding
0.51	GO:0005102	receptor binding
0.46	GO:0008517	folic acid transmembrane transporter activity
0.45	GO:0015250	water channel activity
0.42	GO:0015171	amino acid transmembrane transporter activity
0.36	GO:0004466	long-chain-acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.63	GO:0061851	leading edge of lamellipodium
0.61	GO:0097197	tetraspanin-enriched microdomain
0.61	GO:0031258	lamellipodium membrane
0.60	GO:0031528	microvillus membrane
0.60	GO:0031527	filopodium membrane
0.60	GO:0071437	invadopodium
0.58	GO:0001726	ruffle
0.56	GO:0016323	basolateral plasma membrane
0.56	GO:0016324	apical plasma membrane
0.56	GO:0045121	membrane raft

0.36

EC:1.3.99.13

GO:0004466

sp|Q86YM7|HOME1_HUMAN
Homer protein homolog 1
Search

HOMER1

0.87	Homer protein like protein 1

0.81	GO:0048875	chemical homeostasis within a tissue
0.80	GO:0048148	behavioral response to cocaine
0.79	GO:0003009	skeletal muscle contraction
0.78	GO:2001256	regulation of store-operated calcium entry
0.77	GO:0090279	regulation of calcium ion import
0.77	GO:0048741	skeletal muscle fiber development
0.77	GO:0051592	response to calcium ion
0.76	GO:0051928	positive regulation of calcium ion transport
0.75	GO:2001257	regulation of cation channel activity
0.50	GO:0006874	cellular calcium ion homeostasis

0.77	GO:0044325	ion channel binding
0.70	GO:0035256	G-protein coupled glutamate receptor binding
0.40	GO:0097110	scaffold protein binding
0.39	GO:0035591	signaling adaptor activity
0.39	GO:0032947	protein complex scaffold activity
0.38	GO:0046982	protein heterodimerization activity
0.38	GO:0042802	identical protein binding

0.80	GO:0043034	costamere
0.75	GO:0030018	Z disc
0.75	GO:0014069	postsynaptic density
0.72	GO:0045177	apical part of cell
0.72	GO:0030424	axon
0.51	GO:0005886	plasma membrane
0.45	GO:0030054	cell junction
0.40	GO:0060076	excitatory synapse
0.40	GO:0043198	dendritic shaft
0.39	GO:0005829	cytosol

sp|Q86YN1|DOPP1_HUMAN
Dolichyldiphosphatase 1
Search

DOLPP1

0.96	Dolichyl pyrophosphate phosphatase 1

0.57	GO:0006487	protein N-linked glycosylation
0.41	GO:0008610	lipid biosynthetic process
0.36	GO:0046465	dolichyl diphosphate metabolic process
0.35	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.35	GO:0008053	mitochondrial fusion
0.33	GO:0090407	organophosphate biosynthetic process

0.64

GO:0047874

dolichyldiphosphatase activity

0.55

GO:0030176

integral component of endoplasmic reticulum membrane

0.64

EC:3.6.1.43

GO:0047874

sp|Q86YN6|PRGC2_HUMAN
Peroxisome proliferator-activated receptor gamma coactivator 1-beta
Search

PPARGC1B

0.97	Peroxisome proliferator-activated receptor gamma coactivator 1-beta

0.73	GO:0010694	positive regulation of alkaline phosphatase activity
0.71	GO:0060346	bone trabecula formation
0.70	GO:0046852	positive regulation of bone remodeling
0.70	GO:0030520	intracellular estrogen receptor signaling pathway
0.69	GO:0045672	positive regulation of osteoclast differentiation
0.69	GO:0045124	regulation of bone resorption
0.69	GO:0006390	mitochondrial transcription
0.65	GO:0032846	positive regulation of homeostatic process
0.65	GO:0001503	ossification
0.61	GO:0042327	positive regulation of phosphorylation

0.86	GO:0030331	estrogen receptor binding
0.76	GO:0003712	transcription cofactor activity
0.74	GO:0050682	AF-2 domain binding
0.63	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.58	GO:0003723	RNA binding
0.34	GO:0008270	zinc ion binding

0.62	GO:0016592	mediator complex
0.51	GO:0005739	mitochondrion

sp|Q86YP4|P66A_HUMAN
Transcriptional repressor p66-alpha
Search

GATAD2A

0.93	LOW QUALITY PROTEIN: transcriptional repressor p66-alpha

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0021995	neuropore closure
0.37	GO:0001842	neural fold formation
0.36	GO:0010172	embryonic body morphogenesis
0.36	GO:0001701	in utero embryonic development
0.35	GO:0001568	blood vessel development
0.35	GO:0012501	programmed cell death

0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0030674	protein binding, bridging

0.61	GO:0016581	NuRD complex
0.38	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

sp|Q86YQ2|LATH_HUMAN
Putative BPIFA4P protein
Search

sp|Q86YQ8|CPNE8_HUMAN
Copine-8
Search

CPNE8

0.88	Copine VIII

0.58	GO:1903861	positive regulation of dendrite extension
0.47	GO:0000038	very long-chain fatty acid metabolic process
0.45	GO:0006635	fatty acid beta-oxidation
0.38	GO:0055085	transmembrane transport

0.41	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0070062	extracellular exosome
0.50	GO:0043025	neuronal cell body
0.48	GO:0043005	neuron projection
0.45	GO:0005777	peroxisome
0.30	GO:0016020	membrane

sp|Q86YR5|GPSM1_HUMAN
G-protein-signaling modulator 1
Search

0.84	G protein signaling modulator 1

0.69	GO:0050790	regulation of catalytic activity
0.53	GO:1905832	positive regulation of spindle assembly
0.53	GO:1904778	positive regulation of protein localization to cell cortex
0.52	GO:0051661	maintenance of centrosome location
0.52	GO:0031291	Ran protein signal transduction
0.50	GO:0000132	establishment of mitotic spindle orientation
0.50	GO:0060236	regulation of mitotic spindle organization
0.49	GO:0007052	mitotic spindle organization
0.36	GO:0051301	cell division
0.35	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity

0.76	GO:0030695	GTPase regulator activity
0.52	GO:0001965	G-protein alpha-subunit binding
0.50	GO:0043621	protein self-association
0.50	GO:0070840	dynein complex binding
0.49	GO:0008022	protein C-terminus binding
0.47	GO:0019904	protein domain specific binding
0.46	GO:0042802	identical protein binding
0.34	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.53	GO:0097575	lateral cell cortex
0.51	GO:0097431	mitotic spindle pole
0.48	GO:0005813	centrosome
0.45	GO:0005829	cytosol
0.43	GO:0005794	Golgi apparatus
0.43	GO:0005654	nucleoplasm
0.41	GO:0043234	protein complex
0.38	GO:0016328	lateral plasma membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0098588	bounding membrane of organelle

sp|Q86YR6|POTED_HUMAN
POTE ankyrin domain family member D
Search

0.69	POTE ankyrin domain family member D

0.30	GO:0071944	cell periphery
0.30	GO:0016020	membrane

sp|Q86YR7|MF2L2_HUMAN
Probable guanine nucleotide exchange factor MCF2L2
Search

0.76	Guanine nucleotide exchange factor DBS

0.74	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.51	GO:0035556	intracellular signal transduction
0.32	GO:0006954	inflammatory response
0.32	GO:0006955	immune response

0.75	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.32	GO:0005149	interleukin-1 receptor binding
0.32	GO:0005125	cytokine activity

0.40	GO:0005622	intracellular
0.32	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|Q86YS3|RFIP4_HUMAN
Rab11 family-interacting protein 4
Search

RAB11FIP4

0.97	Rab11 family-interacting protein 4

0.71	GO:1903452	positive regulation of G1 to G0 transition
0.65	GO:0003407	neural retina development
0.64	GO:0032465	regulation of cytokinesis
0.44	GO:0048592	eye morphogenesis
0.39	GO:0051301	cell division
0.39	GO:0007049	cell cycle
0.35	GO:0016032	viral process
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.72	GO:0030306	ADP-ribosylation factor binding
0.66	GO:0017137	Rab GTPase binding
0.65	GO:0005509	calcium ion binding
0.62	GO:0042803	protein homodimerization activity
0.35	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003676	nucleic acid binding

0.70	GO:0055038	recycling endosome membrane
0.69	GO:0097610	cell surface furrow
0.67	GO:0030496	midbody
0.66	GO:0032155	cell division site part
0.66	GO:0030139	endocytic vesicle
0.61	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005615	extracellular space
0.37	GO:0005819	spindle
0.37	GO:0005815	microtubule organizing center

sp|Q86YS6|RAB43_HUMAN
Ras-related protein Rab-43
Search

RAB43

0.93	RAB43, member RAS oncogene family

0.57	GO:0035526	retrograde transport, plasma membrane to Golgi
0.53	GO:0090382	phagosome maturation
0.52	GO:0007030	Golgi organization
0.50	GO:0071346	cellular response to interferon-gamma
0.48	GO:1901998	toxin transport
0.47	GO:0019068	virion assembly
0.34	GO:0051382	kinetochore assembly
0.34	GO:0070507	regulation of microtubule cytoskeleton organization
0.33	GO:0006281	DNA repair

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding

0.52	GO:0045335	phagocytic vesicle
0.49	GO:0005794	Golgi apparatus
0.43	GO:0005768	endosome
0.38	GO:0030666	endocytic vesicle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0031984	organelle subcompartment
0.34	GO:0043025	neuronal cell body
0.33	GO:0045202	synapse
0.33	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:3.1.4.12	GO:0004767
0.36	KEGG:R02541	GO:0004767

sp|Q86YS7|C2CD5_HUMAN
C2 domain-containing protein 5
Search

C2CD5

0.93	C2 calcium dependent domain containing 5

0.85	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase
0.83	GO:0090314	positive regulation of protein targeting to membrane
0.83	GO:0031340	positive regulation of vesicle fusion
0.80	GO:0010828	positive regulation of glucose transport
0.79	GO:2001273	regulation of glucose import in response to insulin stimulus
0.78	GO:1900078	positive regulation of cellular response to insulin stimulus
0.74	GO:0072659	protein localization to plasma membrane
0.73	GO:0006906	vesicle fusion
0.69	GO:0065002	intracellular protein transmembrane transport

0.75	GO:0005544	calcium-dependent phospholipid binding
0.65	GO:0005509	calcium ion binding

0.80	GO:0032587	ruffle membrane
0.71	GO:0030659	cytoplasmic vesicle membrane
0.71	GO:0005938	cell cortex
0.68	GO:0005815	microtubule organizing center
0.62	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q86YT5|S13A5_HUMAN
Solute carrier family 13 member 5
Search

SLC13A5

0.96	Sodium-dependent citrate transporter

0.73	GO:0006814	sodium ion transport
0.58	GO:0035674	tricarboxylic acid transmembrane transport
0.57	GO:0071422	succinate transmembrane transport
0.55	GO:0015746	citrate transport
0.34	GO:0006357	regulation of transcription by RNA polymerase II

0.57	GO:0015141	succinate transmembrane transporter activity
0.54	GO:0015137	citrate transmembrane transporter activity
0.48	GO:0017153	sodium:dicarboxylate symporter activity
0.34	GO:0001104	RNA polymerase II transcription cofactor activity

0.42	GO:0005886	plasma membrane
0.34	GO:0016592	mediator complex
0.30	GO:0016021	integral component of membrane

sp|Q86YT6|MIB1_HUMAN
E3 ubiquitin-protein ligase MIB1
Search

MIB1

0.90	Mindbomb E3 ubiquitin protein ligase 1

0.73	GO:0016567	protein ubiquitination
0.66	GO:0001947	heart looping
0.66	GO:0001756	somitogenesis
0.65	GO:0001841	neural tube formation
0.65	GO:0045807	positive regulation of endocytosis
0.65	GO:0007219	Notch signaling pathway
0.64	GO:0045665	negative regulation of neuron differentiation
0.62	GO:0001568	blood vessel development
0.60	GO:0001701	in utero embryonic development
0.47	GO:0006897	endocytosis

0.73	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0008270	zinc ion binding
0.48	GO:0016874	ligase activity

0.62	GO:0005813	centrosome
0.57	GO:0031410	cytoplasmic vesicle
0.38	GO:0014069	postsynaptic density
0.34	GO:0030529	intracellular ribonucleoprotein complex

0.48	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q86YT9|JAML_HUMAN
Junctional adhesion molecule-like
Search

JAML

0.87	Junction adhesion molecule like

0.87	GO:0046629	gamma-delta T cell activation
0.83	GO:0050900	leukocyte migration
0.65	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing
0.62	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.59	GO:0060326	cell chemotaxis
0.30	GO:0048583	regulation of response to stimulus
0.30	GO:0002682	regulation of immune system process

0.61	GO:0005178	integrin binding
0.56	GO:0042803	protein homodimerization activity

0.59	GO:0005923	bicellular tight junction
0.45	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q86YV0|RASL3_HUMAN
RAS protein activator like-3
Search

RASAL3

0.97	RAS protein activator like-3

0.75	GO:0043087	regulation of GTPase activity
0.75	GO:0051140	regulation of NK T cell proliferation
0.74	GO:0051135	positive regulation of NK T cell activation
0.72	GO:0046641	positive regulation of alpha-beta T cell proliferation
0.72	GO:0051345	positive regulation of hydrolase activity
0.70	GO:0046580	negative regulation of Ras protein signal transduction
0.61	GO:0007165	signal transduction
0.41	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.40	GO:0016525	negative regulation of angiogenesis
0.39	GO:0008285	negative regulation of cell proliferation

0.74	GO:0005096	GTPase activator activity
0.39	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.36	GO:0008270	zinc ion binding

0.63	GO:0098562	cytoplasmic side of membrane
0.48	GO:0031226	intrinsic component of plasma membrane
0.44	GO:0005938	cell cortex
0.43	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol

0.39

EC:3.5.1.28

GO:0008745

sp|Q86YV5|SG223_HUMAN
Tyrosine-protein kinase SgK223
Search

PRAG1

0.89	PEAK1 related kinase activating pseudokinase 1

0.63

GO:0006468

protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

sp|Q86YV6|MYLK4_HUMAN
Myosin light chain kinase family member 4
Search

MYLK4

0.94	Myosin light chain kinase 3

0.62	GO:0006468	protein phosphorylation
0.55	GO:0002528	regulation of vascular permeability involved in acute inflammatory response
0.52	GO:0030239	myofibril assembly
0.52	GO:0071347	cellular response to interleukin-1
0.51	GO:0018210	peptidyl-threonine modification
0.50	GO:0018209	peptidyl-serine modification
0.45	GO:0055013	cardiac muscle cell development
0.43	GO:0035556	intracellular signal transduction
0.38	GO:0060298	positive regulation of sarcomere organization
0.35	GO:0055012	ventricular cardiac muscle cell differentiation

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0015629	actin cytoskeleton
0.38	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0030906	retromer, cargo-selective complex
0.30	GO:0016021	integral component of membrane

sp|Q86YV9|HPS6_HUMAN
Hermansky-Pudlak syndrome 6 protein
Search

HPS6

0.97	Hermansky-Pudlak syndrome 6

0.86	GO:0030318	melanocyte differentiation
0.82	GO:0007596	blood coagulation
0.80	GO:0032418	lysosome localization
0.73	GO:0072657	protein localization to membrane
0.64	GO:0006996	organelle organization
0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0010467	gene expression
0.35	GO:0009059	macromolecule biosynthetic process

0.82	GO:0030742	GTP-dependent protein binding
0.74	GO:0017137	Rab GTPase binding
0.37	GO:0003735	structural constituent of ribosome

0.87	GO:0031084	BLOC-2 complex
0.85	GO:0031901	early endosome membrane
0.75	GO:0005765	lysosomal membrane
0.70	GO:0005783	endoplasmic reticulum
0.36	GO:0005840	ribosome

sp|Q86YW0|PLCZ1_HUMAN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
Search

0.52	Phosphoinositide phospholipase C

0.74	GO:0007343	egg activation
0.72	GO:0016042	lipid catabolic process
0.65	GO:0006816	calcium ion transport
0.62	GO:0035556	intracellular signal transduction
0.53	GO:0001525	angiogenesis
0.50	GO:0042127	regulation of cell proliferation
0.40	GO:0007340	acrosome reaction
0.37	GO:0046488	phosphatidylinositol metabolic process
0.32	GO:0065009	regulation of molecular function

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.63	GO:0004871	signal transducer activity
0.60	GO:0005509	calcium ion binding
0.32	GO:0005085	guanyl-nucleotide exchange factor activity

0.59	GO:0005829	cytosol
0.35	GO:0031965	nuclear membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

sp|Q86YW5|TRML1_HUMAN
Trem-like transcript 1 protein
Search

TREML1

0.97	Triggering receptor expressed on myeloid cells like 1

0.38	GO:0030168	platelet activation
0.38	GO:0019722	calcium-mediated signaling

0.39	GO:0031091	platelet alpha granule
0.37	GO:0009986	cell surface
0.30	GO:0044425	membrane part

sp|Q86YW7|GPHB5_HUMAN
Glycoprotein hormone beta-5
Search

GPHB5

0.97	Glycoprotein hormone beta-5

0.75	GO:0010469	regulation of receptor activity
0.67	GO:0002155	regulation of thyroid hormone mediated signaling pathway
0.62	GO:0030819	positive regulation of cAMP biosynthetic process
0.52	GO:0007166	cell surface receptor signaling pathway
0.48	GO:0009755	hormone-mediated signaling pathway
0.47	GO:0007267	cell-cell signaling
0.46	GO:0007186	G-protein coupled receptor signaling pathway

0.79	GO:0005179	hormone activity
0.65	GO:0031531	thyrotropin-releasing hormone receptor binding
0.54	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q86YW9|MD12L_HUMAN
Mediator of RNA polymerase II transcription subunit 12-like protein
Search

MED12

0.82	Mediator of RNA polymerase II transcription subunit 12

0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0090245	axis elongation involved in somitogenesis
0.47	GO:0048702	embryonic neurocranium morphogenesis
0.47	GO:1990403	embryonic brain development
0.46	GO:0036342	post-anal tail morphogenesis
0.46	GO:0030521	androgen receptor signaling pathway
0.46	GO:0014003	oligodendrocyte development
0.46	GO:0014044	Schwann cell development

0.79	GO:0008013	beta-catenin binding
0.74	GO:0001104	RNA polymerase II transcription cofactor activity
0.53	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.51	GO:0003713	transcription coactivator activity
0.47	GO:0046966	thyroid hormone receptor binding
0.46	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.45	GO:0008022	protein C-terminus binding
0.43	GO:0003682	chromatin binding
0.43	GO:0019904	protein domain specific binding
0.40	GO:0004872	receptor activity

0.76	GO:0016592	mediator complex
0.37	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

sp|Q86YZ3|HORN_HUMAN
Hornerin
Search

HRNR

0.94

Hornerin

0.59	GO:0061436	establishment of skin barrier
0.49	GO:0031424	keratinization
0.48	GO:0043312	neutrophil degranulation
0.47	GO:0043163	cell envelope organization
0.39	GO:0002244	hematopoietic progenitor cell differentiation
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0071277	cellular response to calcium ion

0.68	GO:0005509	calcium ion binding
0.57	GO:0046914	transition metal ion binding
0.46	GO:0005198	structural molecule activity
0.36	GO:0003723	RNA binding
0.35	GO:0003713	transcription coactivator activity
0.35	GO:0046965	retinoid X receptor binding
0.35	GO:0042802	identical protein binding
0.35	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0046966	thyroid hormone receptor binding
0.35	GO:0031489	myosin V binding

0.69	GO:0001533	cornified envelope
0.56	GO:0036457	keratohyalin granule
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0035578	azurophil granule lumen
0.46	GO:0070062	extracellular exosome
0.40	GO:0005634	nucleus
0.39	GO:1904724	tertiary granule lumen
0.35	GO:0044327	dendritic spine head
0.35	GO:0043204	perikaryon
0.34	GO:0005844	polysome

0.31

GO:0016887

sp|Q86Z02|HIPK1_HUMAN
Homeodomain-interacting protein kinase 1
Search

HIPK1

0.88	Homeodomain-interacting protein kinase 1

0.70	GO:0060235	lens induction in camera-type eye
0.69	GO:0061072	iris morphogenesis
0.68	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.68	GO:0072577	endothelial cell apoptotic process
0.67	GO:0010842	retina layer formation
0.67	GO:0048596	embryonic camera-type eye morphogenesis
0.67	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.65	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
0.64	GO:0007224	smoothened signaling pathway
0.64	GO:0097191	extrinsic apoptotic signaling pathway

0.63	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.46	GO:0003677	DNA binding
0.46	GO:0046790	virion binding
0.44	GO:0001105	RNA polymerase II transcription coactivator activity
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.44	GO:0003714	transcription corepressor activity

0.65	GO:0016605	PML body
0.60	GO:0016607	nuclear speck
0.59	GO:0005813	centrosome
0.53	GO:0005829	cytosol
0.42	GO:0090575	RNA polymerase II transcription factor complex
0.32	GO:0005840	ribosome

sp|Q86Z14|KLOTB_HUMAN
Beta-klotho
Search

KLB

0.92	Beta-klotho

0.68	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0008284	positive regulation of cell proliferation
0.51	GO:0008286	insulin receptor signaling pathway
0.49	GO:0007568	aging
0.44	GO:1901657	glycosyl compound metabolic process
0.43	GO:0030501	positive regulation of bone mineralization
0.42	GO:0055074	calcium ion homeostasis
0.41	GO:0006112	energy reserve metabolic process
0.37	GO:0051897	positive regulation of protein kinase B signaling

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.66	GO:0017134	fibroblast growth factor binding
0.64	GO:0005104	fibroblast growth factor receptor binding
0.43	GO:0004871	signal transducer activity
0.38	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0005499	vitamin D binding
0.33	GO:0005179	hormone activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.47	GO:0005615	extracellular space
0.45	GO:0005887	integral component of plasma membrane
0.35	GO:0016324	apical plasma membrane
0.35	GO:1903561	extracellular vesicle
0.33	GO:0005903	brush border
0.32	GO:0005622	intracellular
0.32	GO:0012505	endomembrane system

0.66	EC:3.2.1	GO:0004553
0.38	KEGG:R04545	GO:0046934

sp|Q86Z20|CC125_HUMAN
Coiled-coil domain-containing protein 125
Search

CCDC125

0.97	Coiled-coil domain-containing protein 125

0.78	GO:2000145	regulation of cell motility
0.67	GO:0035024	negative regulation of Rho protein signal transduction
0.64	GO:0090630	activation of GTPase activity
0.63	GO:0051271	negative regulation of cellular component movement
0.63	GO:0040013	negative regulation of locomotion

0.42

GO:0005737

cytoplasm

sp|Q86Z23|C1QL4_HUMAN
Complement C1q-like protein 4
Search

C1QL4

0.97	Complement component 1, q subcomponent-like 4

0.61	GO:0048147	negative regulation of fibroblast proliferation
0.60	GO:0045599	negative regulation of fat cell differentiation
0.59	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.51	GO:0061743	motor learning
0.51	GO:0099558	maintenance of synapse structure
0.50	GO:0016322	neuron remodeling
0.48	GO:0050807	regulation of synapse organization
0.34	GO:0007626	locomotory behavior
0.34	GO:0007017	microtubule-based process

0.57	GO:0042802	identical protein binding
0.44	GO:0005102	receptor binding

0.65	GO:0005581	collagen trimer
0.62	GO:0005576	extracellular region
0.52	GO:0044301	climbing fiber
0.46	GO:0098793	presynapse
0.37	GO:0005737	cytoplasm
0.34	GO:0005869	dynactin complex
0.30	GO:0016020	membrane

sp|Q8HWS3|RFX6_HUMAN
DNA-binding protein RFX6
Search

RFX6

0.96	Regulatory factor X domain-containing protein 1 (Fragment)

0.80	GO:0003311	pancreatic D cell differentiation
0.80	GO:0090104	pancreatic epsilon cell differentiation
0.77	GO:0003310	pancreatic A cell differentiation
0.75	GO:0003309	type B pancreatic cell differentiation
0.74	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.68	GO:0042593	glucose homeostasis
0.67	GO:0006366	transcription by RNA polymerase II
0.66	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
0.46	GO:0021516	dorsal spinal cord development

0.71	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.70	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.57	GO:0000987	proximal promoter sequence-specific DNA binding
0.44	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0003682	chromatin binding

0.63

GO:0005730

nucleolus

sp|Q8IU54|IFNL1_HUMAN
Interferon lambda-1
Search

0.97	Interferon lambda

0.85	GO:0007259	JAK-STAT cascade
0.79	GO:0050778	positive regulation of immune response
0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0050863	regulation of T cell activation
0.55	GO:0045345	positive regulation of MHC class I biosynthetic process
0.55	GO:0032696	negative regulation of interleukin-13 production
0.55	GO:0032714	negative regulation of interleukin-5 production
0.54	GO:0045087	innate immune response
0.54	GO:0002829	negative regulation of type 2 immune response

0.81	GO:0005125	cytokine activity
0.57	GO:0032003	interleukin-28 receptor binding

0.56	GO:0032002	interleukin-28 receptor complex
0.51	GO:0005576	extracellular region
0.45	GO:0005622	intracellular

sp|Q8IU57|INLR1_HUMAN
Interferon lambda receptor 1
Search

IFNLR1

0.93	Interferon lambda receptor 1

0.76	GO:0050691	regulation of defense response to virus by host
0.74	GO:0002385	mucosal immune response
0.65	GO:0051607	defense response to virus
0.53	GO:0019221	cytokine-mediated signaling pathway
0.50	GO:0034342	response to type III interferon
0.41	GO:0008285	negative regulation of cell proliferation

0.54	GO:0004896	cytokine receptor activity
0.38	GO:0005515	protein binding

0.83

GO:0032002

interleukin-28 receptor complex

sp|Q8IU60|DCP2_HUMAN
m7GpppN-mRNA hydrolase
Search

DCP2

0.91	mRNA decapping enzyme

0.59	GO:0071044	histone mRNA catabolic process
0.59	GO:1904872	regulation of telomerase RNA localization to Cajal body
0.58	GO:0032211	negative regulation of telomere maintenance via telomerase
0.52	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.49	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.37	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.36	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.35	GO:0043488	regulation of mRNA stability

0.71	GO:0030145	manganese ion binding
0.60	GO:0050072	m7G(5')pppN diphosphatase activity
0.58	GO:0003723	RNA binding
0.54	GO:0004534	5'-3' exoribonuclease activity
0.33	GO:0005515	protein binding

0.56	GO:0016442	RISC complex
0.56	GO:0000932	P-body
0.51	GO:0030054	cell junction
0.48	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.60

EC:3.6.1.30

GO:0050072

sp|Q8IU68|TMC8_HUMAN
Transmembrane channel-like protein 8
Search

TMC8

0.72	Transmembrane channel-like protein 8

0.65	GO:0032460	negative regulation of protein oligomerization
0.64	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.63	GO:0055069	zinc ion homeostasis
0.62	GO:0032091	negative regulation of protein binding
0.59	GO:0001558	regulation of cell growth
0.36	GO:0006811	ion transport

0.55	GO:0005102	receptor binding
0.36	GO:0030246	carbohydrate binding

0.59	GO:0031965	nuclear membrane
0.54	GO:0005794	Golgi apparatus
0.54	GO:0005783	endoplasmic reticulum
0.41	GO:0070062	extracellular exosome
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IU80|TMPS6_HUMAN
Transmembrane protease serine 6
Search

TMPRSS6

0.95	Transmembrane protease serine 6

0.60	GO:0042730	fibrinolysis
0.60	GO:0006508	proteolysis
0.58	GO:0030514	negative regulation of BMP signaling pathway
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0006879	cellular iron ion homeostasis
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0032501	multicellular organismal process
0.37	GO:0022617	extracellular matrix disassembly
0.36	GO:0009653	anatomical structure morphogenesis
0.35	GO:0007599	hemostasis

0.68	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0004896	cytokine receptor activity
0.34	GO:0005515	protein binding
0.34	GO:0004792	thiosulfate sulfurtransferase activity
0.34	GO:0005509	calcium ion binding

0.52	GO:0005615	extracellular space
0.44	GO:0005886	plasma membrane
0.34	GO:0043025	neuronal cell body
0.33	GO:0031982	vesicle
0.33	GO:0043230	extracellular organelle
0.33	GO:0030425	dendrite
0.32	GO:0005622	intracellular
0.32	GO:0012505	endomembrane system
0.32	GO:0045177	apical part of cell
0.32	GO:0009986	cell surface

0.68	EC:3.4.21	GO:0004252
0.34	KEGG:R01931	GO:0004792

sp|Q8IU81|I2BP1_HUMAN
Interferon regulatory factor 2-binding protein 1
Search

IRF2BP1

0.94	Interferon regulatory factor 2 binding protein 1

0.39	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0006417	regulation of translation
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II

0.53	GO:0046872	metal ion binding
0.38	GO:0003714	transcription corepressor activity
0.38	GO:0005515	protein binding
0.35	GO:0016740	transferase activity
0.35	GO:0003723	RNA binding

0.58

GO:0005654

nucleoplasm

0.35

EC:2

GO:0016740

sp|Q8IU85|KCC1D_HUMAN
Calcium/calmodulin-dependent protein kinase type 1D
Search

CAMK1D

0.87	Calcium/calmodulin-dependent protein kinase ID

0.81	GO:0060267	positive regulation of respiratory burst
0.77	GO:0090023	positive regulation of neutrophil chemotaxis
0.77	GO:0032793	positive regulation of CREB transcription factor activity
0.77	GO:0050766	positive regulation of phagocytosis
0.74	GO:0050773	regulation of dendrite development
0.73	GO:0010976	positive regulation of neuron projection development
0.69	GO:0043065	positive regulation of apoptotic process
0.69	GO:0043066	negative regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.58	GO:0018210	peptidyl-threonine modification

0.64	GO:0004672	protein kinase activity
0.56	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm

sp|Q8IU89|CERS3_HUMAN
Ceramide synthase 3
Search

CERS3

0.95	Ceramide synthase 3

0.66	GO:0046513	ceramide biosynthetic process
0.59	GO:0030216	keratinocyte differentiation
0.38	GO:1900148	negative regulation of Schwann cell migration
0.38	GO:1905045	negative regulation of Schwann cell proliferation involved in axon regeneration
0.33	GO:0006508	proteolysis

0.67	GO:0050291	sphingosine N-acyltransferase activity
0.53	GO:0003677	DNA binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0046872	metal ion binding

0.59	GO:0005634	nucleus
0.48	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.35	GO:0031984	organelle subcompartment
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.67

EC:2.3.1.24

GO:0050291

sp|Q8IU99|CAHM1_HUMAN
Calcium homeostasis modulator protein 1
Search

CALHM1

0.97	Calcium homeostasis modulator protein 1

0.61	GO:0050917	sensory perception of umami taste
0.60	GO:0050916	sensory perception of sweet taste
0.59	GO:0098655	cation transmembrane transport
0.59	GO:0050913	sensory perception of bitter taste
0.57	GO:0015867	ATP transport
0.55	GO:0051260	protein homooligomerization
0.54	GO:0034765	regulation of ion transmembrane transport
0.54	GO:0006816	calcium ion transport
0.46	GO:0098660	inorganic ion transmembrane transport

0.79	GO:0005227	calcium activated cation channel activity
0.72	GO:0022832	voltage-gated channel activity
0.55	GO:0005262	calcium channel activity
0.52	GO:0042802	identical protein binding

0.50	GO:0005887	integral component of plasma membrane
0.36	GO:0005789	endoplasmic reticulum membrane

sp|Q8IUA0|WFDC8_HUMAN
WAP four-disulfide core domain protein 8
Search

WFDC8

0.97	LOW QUALITY PROTEIN: WAP four-disulfide core domain protein 8

0.76	GO:0010466	negative regulation of peptidase activity
0.76	GO:0052548	regulation of endopeptidase activity
0.43	GO:0007596	blood coagulation
0.39	GO:0006508	proteolysis
0.37	GO:0006030	chitin metabolic process
0.35	GO:1900116	extracellular negative regulation of signal transduction
0.34	GO:0043392	negative regulation of DNA binding
0.34	GO:0060021	palate development
0.34	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.34	GO:0048747	muscle fiber development

0.78	GO:0004867	serine-type endopeptidase inhibitor activity
0.39	GO:0008233	peptidase activity
0.37	GO:0008061	chitin binding
0.35	GO:0050431	transforming growth factor beta binding
0.35	GO:0048019	receptor antagonist activity
0.33	GO:0008191	metalloendopeptidase inhibitor activity
0.33	GO:0005201	extracellular matrix structural constituent
0.33	GO:0090729	toxin activity
0.31	GO:0003676	nucleic acid binding

0.63	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.39

GO:0008233

sp|Q8IUA7|ABCA9_HUMAN
ATP-binding cassette sub-family A member 9
Search

0.94	ATP-binding cassette sub-family A member 8-B

0.56	GO:0006869	lipid transport
0.54	GO:0055085	transmembrane transport
0.34	GO:0042908	xenobiotic transport
0.33	GO:0015893	drug transport

0.64	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0042910	xenobiotic transmembrane transporter activity
0.33	GO:0015238	drug transmembrane transporter activity

0.47	GO:0043231	intracellular membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.44	GO:0044444	cytoplasmic part
0.43	GO:0031974	membrane-enclosed lumen
0.42	GO:0031090	organelle membrane
0.41	GO:0031975	envelope
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IUB2|WFDC3_HUMAN
WAP four-disulfide core domain protein 3
Search

WFDC3

0.93	WAP four-disulfide core domain protein 3

0.76	GO:0010466	negative regulation of peptidase activity
0.47	GO:0052548	regulation of endopeptidase activity
0.36	GO:0006508	proteolysis
0.35	GO:0007620	copulation

0.76	GO:0030414	peptidase inhibitor activity
0.48	GO:0061135	endopeptidase regulator activity
0.37	GO:0008233	peptidase activity

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.37

GO:0008233

sp|Q8IUB3|WF10B_HUMAN
Protein WFDC10B
Search

WFDC10A

0.97	WAP four-disulfide core domain protein 10A

0.76	GO:0010466	negative regulation of peptidase activity
0.41	GO:0052548	regulation of endopeptidase activity

0.76	GO:0030414	peptidase inhibitor activity
0.41	GO:0061135	endopeptidase regulator activity

0.66

GO:0005576

extracellular region

sp|Q8IUB5|WFD13_HUMAN
WAP four-disulfide core domain protein 13
Search

sp|Q8IUB9|KR191_HUMAN
Keratin-associated protein 19-1
Search

0.97	High tyrosine-glycine keratin-associated protein 19.1

0.62	GO:0031424	keratinization
0.45	GO:0016560	protein import into peroxisome matrix, docking
0.41	GO:0070830	bicellular tight junction assembly
0.39	GO:0070673	response to interleukin-18
0.38	GO:0071356	cellular response to tumor necrosis factor
0.36	GO:0006413	translational initiation
0.35	GO:0007010	cytoskeleton organization

0.41	GO:0005515	protein binding
0.38	GO:0030246	carbohydrate binding
0.38	GO:0005198	structural molecule activity
0.36	GO:0003743	translation initiation factor activity
0.35	GO:0004386	helicase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0005882	intermediate filament
0.51	GO:0005829	cytosol
0.43	GO:0042579	microbody
0.41	GO:0016327	apicolateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.40	GO:0030139	endocytic vesicle
0.40	GO:0005923	bicellular tight junction
0.38	GO:0016328	lateral plasma membrane
0.37	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016021	integral component of membrane

sp|Q8IUC0|KR131_HUMAN
Keratin-associated protein 13-1
Search

0.97	Keratin-associated protein 14

0.60

GO:0031424

keratinization

0.39

GO:0005515

protein binding

0.75	GO:0005882	intermediate filament
0.50	GO:0005829	cytosol

sp|Q8IUC1|KR111_HUMAN
Keratin-associated protein 11-1
Search

KRTAP11-1

0.92	High sulfur keratin-associated protein 11.1

0.46	GO:0031424	keratinization
0.34	GO:0009405	pathogenesis
0.33	GO:0065009	regulation of molecular function

0.55	GO:0005198	structural molecule activity
0.35	GO:0019855	calcium channel inhibitor activity

0.79	GO:0045095	keratin filament
0.41	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

sp|Q8IUC2|KRA81_HUMAN
Keratin-associated protein 8-1
Search

KRTAP8-1

0.97	Keratin associated protein 8

0.79

GO:0005882

intermediate filament

sp|Q8IUC3|KRA71_HUMAN
Keratin-associated protein 7-1
Search

0.79

GO:0005882

intermediate filament

sp|Q8IUC4|RHPN2_HUMAN
Rhophilin-2
Search

RHPN2

0.62	Rhophilin Rho GTPase binding protein 2

0.59

GO:0007165

signal transduction

0.41	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005829	cytosol

sp|Q8IUC6|TCAM1_HUMAN
TIR domain-containing adapter molecule 1
Search

TICAM1

0.95	TIR domain-containing adapter molecule 1

0.79	GO:0045087	innate immune response
0.63	GO:0035666	TRIF-dependent toll-like receptor signaling pathway
0.63	GO:0043330	response to exogenous dsRNA
0.63	GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus
0.62	GO:0045359	positive regulation of interferon-beta biosynthetic process
0.62	GO:0045080	positive regulation of chemokine biosynthetic process
0.62	GO:0002281	macrophage activation involved in immune response
0.61	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.61	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.61	GO:0032816	positive regulation of natural killer cell activation

0.64	GO:0004871	signal transducer activity
0.58	GO:0019901	protein kinase binding
0.33	GO:0008236	serine-type peptidase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0097342	ripoptosome
0.43	GO:0005776	autophagosome
0.40	GO:0031410	cytoplasmic vesicle
0.38	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0012505	endomembrane system
0.35	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

sp|Q8IUC8|GLT13_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 13
Search

GALNT13

0.65	Polypeptide N-acetylgalactosaminyltransferase

0.73	GO:0006486	protein glycosylation
0.58	GO:0018210	peptidyl-threonine modification
0.56	GO:0018209	peptidyl-serine modification

0.69	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.45	GO:0030145	manganese ion binding
0.45	GO:0140096	catalytic activity, acting on a protein

0.73	GO:0000139	Golgi membrane
0.48	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031985	Golgi cisterna
0.34	GO:0005576	extracellular region
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

sp|Q8IUD2|RB6I2_HUMAN
ELKS/Rab6-interacting/CAST family member 1
Search

ERC1

0.91	Putative rab6 gtpase-interacting protein involved in endosome-to-tgn transport

0.59	GO:0007252	I-kappaB phosphorylation
0.37	GO:0042147	retrograde transport, endosome to Golgi
0.35	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.35	GO:0015031	protein transport
0.35	GO:0043066	negative regulation of apoptotic process
0.34	GO:0007275	multicellular organism development
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:1901566	organonitrogen compound biosynthetic process
0.32	GO:0010467	gene expression

0.55	GO:0045296	cadherin binding
0.38	GO:0030165	PDZ domain binding
0.37	GO:0017137	Rab GTPase binding
0.36	GO:0043522	leucine zipper domain binding
0.32	GO:0003735	structural constituent of ribosome

0.83	GO:0048786	presynaptic active zone
0.60	GO:0008385	IkappaB kinase complex
0.36	GO:0000139	Golgi membrane
0.36	GO:0042734	presynaptic membrane
0.32	GO:0005840	ribosome

sp|Q8IUD6|RN135_HUMAN
E3 ubiquitin-protein ligase RNF135
Search

RNF135

0.93	Ring finger protein 135

0.64	GO:0032728	positive regulation of interferon-beta production
0.58	GO:0016567	protein ubiquitination
0.57	GO:0080134	regulation of response to stress
0.55	GO:0050776	regulation of immune response
0.43	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.42	GO:0045087	innate immune response
0.42	GO:0023051	regulation of signaling
0.42	GO:0010646	regulation of cell communication
0.42	GO:0043066	negative regulation of apoptotic process
0.41	GO:0048585	negative regulation of response to stimulus

0.58	GO:0004842	ubiquitin-protein transferase activity
0.56	GO:0042802	identical protein binding
0.55	GO:0043021	ribonucleoprotein complex binding
0.49	GO:0046872	metal ion binding
0.46	GO:0089720	caspase binding
0.44	GO:0016874	ligase activity
0.44	GO:0030674	protein binding, bridging
0.43	GO:0061659	ubiquitin-like protein ligase activity
0.38	GO:1902936	phosphatidylinositol bisphosphate binding
0.37	GO:0005096	GTPase activator activity

0.42	GO:0005737	cytoplasm
0.39	GO:0012505	endomembrane system
0.38	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0031968	organelle outer membrane
0.36	GO:0031301	integral component of organelle membrane
0.33	GO:0031984	organelle subcompartment
0.33	GO:0019005	SCF ubiquitin ligase complex
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0005887	integral component of plasma membrane

0.44	EC:6	GO:0016874
0.58	KEGG:R03876	GO:0004842

sp|Q8IUE0|TF2LY_HUMAN
Homeobox protein TGIF2LY
Search

TGIF2LX

0.97	Homeobox protein TGIF2LY

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0006351	transcription, DNA-templated
0.37	GO:0007283	spermatogenesis
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.33	GO:0006270	DNA replication initiation
0.33	GO:0016310	phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0003677	DNA binding
0.37	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0019205	nucleobase-containing compound kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004497	monooxygenase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q8IUE1|TF2LX_HUMAN
Homeobox protein TGIF2LX
Search

TGIF2LX

0.94	TGFB-induced factor 2-like protein, X-linked

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0006351	transcription, DNA-templated
0.36	GO:0007283	spermatogenesis
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.33	GO:0006270	DNA replication initiation
0.33	GO:0016310	phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0003677	DNA binding
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0019205	nucleobase-containing compound kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004497	monooxygenase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q8IUE6|H2A2B_HUMAN
Histone H2A type 2-B
Search

sp|Q8IUF1|CBWD2_HUMAN
COBW domain-containing protein 2
Search

0.71	Cobalamin synthase W domain-containing protein 3

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding

sp|Q8IUF8|MINA_HUMAN
Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA
Search

RIOX2

0.94	Ribosomal oxygenase 2

0.74	GO:0000122	negative regulation of transcription by RNA polymerase II
0.66	GO:0030961	peptidyl-arginine hydroxylation
0.64	GO:0070544	histone H3-K36 demethylation
0.63	GO:0034720	histone H3-K4 demethylation
0.57	GO:0006338	chromatin remodeling
0.46	GO:0042254	ribosome biogenesis
0.42	GO:0006351	transcription, DNA-templated
0.40	GO:0055114	oxidation-reduction process
0.39	GO:0008283	cell proliferation
0.39	GO:0042127	regulation of cell proliferation

0.82	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.72	GO:0042802	identical protein binding
0.64	GO:0032453	histone demethylase activity (H3-K4 specific)
0.64	GO:0051864	histone demethylase activity (H3-K36 specific)
0.40	GO:0046872	metal ion binding

0.73	GO:0005730	nucleolus
0.71	GO:0005667	transcription factor complex
0.68	GO:0005829	cytosol
0.38	GO:0005654	nucleoplasm

0.64

EC:1.14.11.27

GO:0051864

sp|Q8IUG1|KRA13_HUMAN
Keratin-associated protein 1-3
Search

0.97	Keratin intermediate-filament type I protein variant 2

0.40

GO:0031424

keratinization

0.37	GO:0030280	structural constituent of epidermis
0.35	GO:0042802	identical protein binding
0.34	GO:0039660	structural constituent of virion

0.83	GO:0045095	keratin filament
0.37	GO:0005829	cytosol

sp|Q8IUG5|MY18B_HUMAN
Unconventional myosin-XVIIIb
Search

MYO18B

0.80	Unconventional myosin-XVIIIb

0.73	GO:0007018	microtubule-based movement
0.61	GO:0048739	cardiac muscle fiber development
0.58	GO:0001570	vasculogenesis
0.55	GO:0001701	in utero embryonic development
0.38	GO:1903028	positive regulation of opsonization
0.38	GO:0090164	asymmetric Golgi ribbon formation
0.37	GO:0043030	regulation of macrophage activation
0.37	GO:0031032	actomyosin structure organization
0.37	GO:0050714	positive regulation of protein secretion
0.37	GO:0048194	Golgi vesicle budding

0.73	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.73	GO:0003779	actin binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0032403	protein complex binding
0.37	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0003677	DNA binding
0.33	GO:0004703	G-protein coupled receptor kinase activity

0.76	GO:0016459	myosin complex
0.58	GO:0031941	filamentous actin
0.57	GO:0030018	Z disc
0.37	GO:0042641	actomyosin
0.36	GO:0005802	trans-Golgi network
0.36	GO:0000139	Golgi membrane
0.34	GO:0005634	nucleus
0.34	GO:0005903	brush border
0.34	GO:0045335	phagocytic vesicle

0.33

EC:2.7.11.16

GO:0004703

sp|Q8IUH2|CREG2_HUMAN
Protein CREG2
Search

CREG2

0.97	Cellular repressor of E1A-stimulated genes 2

0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:0010468	regulation of gene expression

0.56	GO:0048037	cofactor binding
0.32	GO:0016874	ligase activity
0.32	GO:0003677	DNA binding

0.56	GO:0005794	Golgi apparatus
0.55	GO:0005783	endoplasmic reticulum
0.37	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.32

GO:0016874

sp|Q8IUH3|RBM45_HUMAN
RNA-binding protein 45
Search

RBM45

0.95	Developmentally regulated RNA-binding protein 1

0.37	GO:0007399	nervous system development
0.37	GO:0030154	cell differentiation

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

sp|Q8IUH4|ZDH13_HUMAN
Palmitoyltransferase ZDHHC13
Search

ZDHHC13

0.58	Palmitoyltransferase

0.77	GO:1903830	magnesium ion transmembrane transport
0.44	GO:0042665	regulation of ectodermal cell fate specification
0.44	GO:0060803	BMP signaling pathway involved in mesodermal cell fate specification
0.41	GO:0030510	regulation of BMP signaling pathway
0.40	GO:0018345	protein palmitoylation
0.39	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.39	GO:0044872	lipoprotein localization
0.37	GO:0015031	protein transport
0.36	GO:0007409	axonogenesis

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.77	GO:0015095	magnesium ion transmembrane transporter activity
0.38	GO:0042802	identical protein binding
0.36	GO:0004871	signal transducer activity

0.57	GO:0030660	Golgi-associated vesicle membrane
0.55	GO:0000139	Golgi membrane
0.52	GO:0005783	endoplasmic reticulum
0.40	GO:0016235	aggresome
0.39	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0016021	integral component of membrane

0.79

GO:0019706

sp|Q8IUH5|ZDH17_HUMAN
Palmitoyltransferase ZDHHC17
Search

ZDHHC17

0.57	Palmitoyltransferase

0.76	GO:1903830	magnesium ion transmembrane transport
0.56	GO:0018345	protein palmitoylation
0.53	GO:0042953	lipoprotein transport
0.44	GO:0007409	axonogenesis
0.38	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0007165	signal transduction

0.78	GO:0016409	palmitoyltransferase activity
0.77	GO:0019707	protein-cysteine S-acyltransferase activity
0.76	GO:0015095	magnesium ion transmembrane transporter activity
0.51	GO:0042802	identical protein binding
0.35	GO:0004871	signal transducer activity

0.57	GO:0016235	aggresome
0.52	GO:0030660	Golgi-associated vesicle membrane
0.51	GO:0000139	Golgi membrane
0.39	GO:0042734	presynaptic membrane
0.37	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.3.1

GO:0016409

sp|Q8IUH8|SPP2C_HUMAN
Signal peptide peptidase-like 2C
Search

SPPL2C

0.83	Intramembrane protease 5

0.76	GO:0031293	membrane protein intracellular domain proteolysis
0.50	GO:0006509	membrane protein ectodomain proteolysis
0.44	GO:0050819	negative regulation of coagulation
0.43	GO:0050776	regulation of immune response
0.34	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.74	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving
0.52	GO:0042803	protein homodimerization activity
0.35	GO:0004930	G-protein coupled receptor activity

0.62	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane
0.62	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.53	GO:0005765	lysosomal membrane
0.51	GO:0030660	Golgi-associated vesicle membrane
0.44	GO:0010008	endosome membrane
0.43	GO:0005813	centrosome
0.42	GO:0015629	actin cytoskeleton
0.41	GO:0005654	nucleoplasm
0.38	GO:0005886	plasma membrane
0.35	GO:0000139	Golgi membrane

0.74

EC:3.4.23

GO:0042500

sp|Q8IUI4|S29P2_HUMAN
Putative protein SNX29P2
Search

SNX29

0.74	Sorting nexin 29

0.37	GO:0007018	microtubule-based movement
0.35	GO:0048741	skeletal muscle fiber development
0.33	GO:0042045	epithelial fluid transport
0.33	GO:0010765	positive regulation of sodium ion transport
0.33	GO:0038166	angiotensin-activated signaling pathway
0.33	GO:0031440	regulation of mRNA 3'-end processing
0.33	GO:0006611	protein export from nucleus
0.33	GO:0044070	regulation of anion transport
0.33	GO:0051592	response to calcium ion
0.33	GO:0097193	intrinsic apoptotic signaling pathway

0.76	GO:0035091	phosphatidylinositol binding
0.37	GO:0003777	microtubule motor activity
0.35	GO:0016887	ATPase activity
0.33	GO:2001070	starch binding
0.33	GO:0004013	adenosylhomocysteinase activity
0.33	GO:0042802	identical protein binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0046872	metal ion binding

0.40	GO:0070062	extracellular exosome
0.38	GO:0005871	kinesin complex
0.32	GO:0005829	cytosol
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016887

sp|Q8IUI8|CRLF3_HUMAN
Cytokine receptor-like factor 3
Search

CRLF3

0.97	Cytokine receptor like factor 3

0.85	GO:0071158	positive regulation of cell cycle arrest
0.84	GO:0046427	positive regulation of JAK-STAT cascade
0.82	GO:0030308	negative regulation of cell growth
0.82	GO:0000082	G1/S transition of mitotic cell cycle
0.74	GO:0045944	positive regulation of transcription by RNA polymerase II

0.73

GO:0042802

identical protein binding

0.67	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IUK5|PLDX1_HUMAN
Plexin domain-containing protein 1
Search

PLXDC1

0.90	Plexin domain-containing protein 1

0.71	GO:0001525	angiogenesis
0.39	GO:0021510	spinal cord development

0.35	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0043235	receptor complex
0.42	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.37	GO:0005923	bicellular tight junction
0.35	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.30	GO:0044425	membrane part

sp|Q8IUK8|CBLN2_HUMAN
Cerebellin-2
Search

CBLN2

0.95	Cerebellin 2 precursor

0.81	GO:0051965	positive regulation of synapse assembly
0.71	GO:1900454	positive regulation of long term synaptic depression
0.69	GO:0090394	negative regulation of excitatory postsynaptic potential
0.68	GO:0021684	cerebellar granular layer formation
0.66	GO:0021533	cell differentiation in hindbrain
0.65	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.62	GO:0021953	central nervous system neuron differentiation
0.55	GO:0009306	protein secretion
0.38	GO:0048168	regulation of neuronal synaptic plasticity
0.36	GO:0007268	chemical synaptic transmission

0.58	GO:0042803	protein homodimerization activity
0.35	GO:0003676	nucleic acid binding
0.33	GO:0046872	metal ion binding

0.60	GO:0005615	extracellular space
0.58	GO:0045202	synapse
0.42	GO:0098590	plasma membrane region
0.41	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|Q8IUL8|CILP2_HUMAN
Cartilage intermediate layer protein 2
Search

CILP

0.95	Cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

0.80

GO:0043569

negative regulation of insulin-like growth factor receptor signaling pathway

0.50	GO:0030246	carbohydrate binding
0.46	GO:0004035	alkaline phosphatase activity
0.45	GO:0004551	nucleotide diphosphatase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003677	DNA binding

0.66	GO:0031012	extracellular matrix
0.66	GO:0005615	extracellular space
0.46	GO:1903561	extracellular vesicle

0.46

EC:3.1.3.1

GO:0004035

sp|Q8IUM7|NPAS4_HUMAN
Neuronal PAS domain-containing protein 4
Search

NPAS4

0.95	Neuronal PAS domain-containing protein 4

0.74	GO:0071386	cellular response to corticosterone stimulus
0.74	GO:1904862	inhibitory synapse assembly
0.72	GO:0060080	inhibitory postsynaptic potential
0.70	GO:0007614	short-term memory
0.69	GO:0032228	regulation of synaptic transmission, GABAergic
0.69	GO:0035176	social behavior
0.69	GO:0007616	long-term memory
0.67	GO:0007612	learning
0.67	GO:0048167	regulation of synaptic plasticity
0.64	GO:0060079	excitatory postsynaptic potential

0.68	GO:0046983	protein dimerization activity
0.66	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0051287	NAD binding
0.37	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.62	GO:0098794	postsynapse
0.61	GO:0005634	nucleus
0.60	GO:0005667	transcription factor complex
0.31	GO:0044446	intracellular organelle part

0.37

EC:1.1.1

GO:0016616

sp|Q8IUN9|CLC10_HUMAN
C-type lectin domain family 10 member A
Search

0.92	Macrophage galactose N-acetyl-galactosamine-specific lectin 2

0.45	GO:0055088	lipid homeostasis
0.45	GO:0031668	cellular response to extracellular stimulus
0.44	GO:0031647	regulation of protein stability
0.43	GO:0009100	glycoprotein metabolic process
0.40	GO:0006897	endocytosis
0.38	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.38	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.37	GO:0030282	bone mineralization
0.37	GO:0002250	adaptive immune response
0.36	GO:0045087	innate immune response

0.69	GO:0030246	carbohydrate binding
0.47	GO:0042803	protein homodimerization activity
0.42	GO:0004873	asialoglycoprotein receptor activity
0.34	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.35	GO:0005581	collagen trimer
0.34	GO:0005886	plasma membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q8IUQ0|CLVS1_HUMAN
Clavesin-1
Search

CLVS1

0.89	Retinaldehyde-binding protein 1-like protein 1

0.84

GO:0007040

lysosome organization

0.85

GO:0080025

phosphatidylinositol-3,5-bisphosphate binding

0.80	GO:0005802	trans-Golgi network
0.80	GO:0030136	clathrin-coated vesicle
0.76	GO:0005768	endosome
0.41	GO:0044433	cytoplasmic vesicle part
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle

sp|Q8IUQ4|SIAH1_HUMAN
E3 ubiquitin-protein ligase SIAH1
Search

SIAH1

0.56	E3 ubiquitin-protein ligase

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.72	GO:0016567	protein ubiquitination
0.70	GO:0007275	multicellular organism development
0.55	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.41	GO:0051402	neuron apoptotic process
0.38	GO:0010498	proteasomal protein catabolic process
0.38	GO:0031648	protein destabilization
0.37	GO:0007283	spermatogenesis
0.37	GO:0007141	male meiosis I
0.36	GO:0040014	regulation of multicellular organism growth

0.63	GO:0008270	zinc ion binding
0.54	GO:0008022	protein C-terminus binding
0.52	GO:0016874	ligase activity
0.51	GO:0061630	ubiquitin protein ligase activity
0.49	GO:0042802	identical protein binding
0.36	GO:0097718	disordered domain specific binding
0.34	GO:0046983	protein dimerization activity

0.61	GO:0005634	nucleus
0.55	GO:0030877	beta-catenin destruction complex
0.37	GO:0005829	cytosol
0.37	GO:0005769	early endosome
0.36	GO:0019005	SCF ubiquitin ligase complex
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.52

GO:0016874

sp|Q8IUR0|TPPC5_HUMAN
Trafficking protein particle complex subunit 5
Search

TRAPPC5

0.93	Trafficking protein particle complex subunit 5

0.76	GO:0048193	Golgi vesicle transport
0.35	GO:0006901	vesicle coating
0.35	GO:0006903	vesicle targeting
0.34	GO:0046907	intracellular transport
0.34	GO:0065009	regulation of molecular function
0.34	GO:0006461	protein complex assembly
0.33	GO:0006979	response to oxidative stress
0.33	GO:0098869	cellular oxidant detoxification
0.32	GO:0055114	oxidation-reduction process

0.36	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0004602	glutathione peroxidase activity

0.82	GO:0030008	TRAPP complex
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005783	endoplasmic reticulum
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0005829	cytosol
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.11.1.9

GO:0004602

sp|Q8IUR5|TMTC1_HUMAN
Transmembrane and TPR repeat-containing protein 1
Search

TMTC1

0.92	Transmembrane and tetratricopeptide repeat containing 1

0.54

GO:0006396

RNA processing

0.38	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|Q8IUR6|CRERF_HUMAN
CREB3 regulatory factor
Search

CREBRF

0.94	CREB3 regulatory factor

0.62	GO:1902213	positive regulation of prolactin signaling pathway
0.62	GO:1900170	negative regulation of glucocorticoid mediated signaling pathway
0.59	GO:0042711	maternal behavior
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0006366	transcription by RNA polymerase II
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.59	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.53	GO:0016604	nuclear body
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IUR7|ARMC8_HUMAN
Armadillo repeat-containing protein 8
Search

ARMC8

0.93	Armadillo repeat-containing protein 8

0.57

GO:0043312

neutrophil degranulation

0.45	GO:0005515	protein binding
0.45	GO:0005198	structural molecule activity

0.60	GO:1904724	tertiary granule lumen
0.60	GO:0035580	specific granule lumen
0.53	GO:0005923	bicellular tight junction
0.47	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IUS5|EPHX4_HUMAN
Epoxide hydrolase 4
Search

EPHX4

0.97	Abhydrolase domain containing 7 (Predicted)

0.43	GO:0097176	epoxide metabolic process
0.33	GO:0006629	lipid metabolic process

0.46	GO:0016787	hydrolase activity
0.34	GO:0016746	transferase activity, transferring acyl groups

0.36	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0031090	organelle membrane
0.33	GO:0044444	cytoplasmic part
0.30	GO:0044425	membrane part

0.46

GO:0016787

sp|Q8IUW3|SPA2L_HUMAN
Spermatogenesis-associated protein 2-like protein
Search

SPATA2L

0.97	Spermatogeneis-associated protein 2

0.40	GO:0006898	receptor-mediated endocytosis
0.37	GO:0006508	proteolysis

0.42	GO:0005044	scavenger receptor activity
0.39	GO:0004252	serine-type endopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.39

GO:0004252

sp|Q8IUW5|RELL1_HUMAN
RELT-like protein 1
Search

RELL1

0.97	Putative tumor necrosis factor receptor superfamily member 19

0.40	GO:0010811	positive regulation of cell-substrate adhesion
0.32	GO:0032259	methylation

0.39	GO:0005518	collagen binding
0.32	GO:0008168	methyltransferase activity

0.53	GO:0015630	microtubule cytoskeleton
0.44	GO:0005886	plasma membrane
0.39	GO:0005604	basement membrane
0.30	GO:0044425	membrane part

0.32

GO:0008168

sp|Q8IUX1|T126B_HUMAN
Complex I assembly factor TMEM126B, mitochondrial
Search

TMEM126B

0.44	Complex I assembly factor TMEM126B, mitochondrial

0.39

GO:0032981

mitochondrial respiratory chain complex I assembly

0.36

GO:0005515

protein binding

0.52	GO:0005739	mitochondrion
0.38	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.30	GO:0044425	membrane part

sp|Q8IUX4|ABC3F_HUMAN
DNA dC->dU-editing enzyme APOBEC-3F
Search

0.73	Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE transcript variant 1

0.48	GO:0010529	negative regulation of transposition
0.45	GO:0009972	cytidine deamination
0.45	GO:0080111	DNA demethylation
0.43	GO:0045071	negative regulation of viral genome replication
0.42	GO:0045087	innate immune response
0.42	GO:0051607	defense response to virus
0.40	GO:0070383	DNA cytosine deamination
0.35	GO:0016032	viral process
0.30	GO:0002682	regulation of immune system process
0.30	GO:0009451	RNA modification

0.72	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.63	GO:0008270	zinc ion binding
0.39	GO:0019239	deaminase activity
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.40	GO:0005634	nucleus
0.38	GO:0000932	P-body
0.30	GO:0043234	protein complex
0.30	GO:0044446	intracellular organelle part

0.72

EC:3.5.4

GO:0016814

sp|Q8IUX7|AEBP1_HUMAN
Adipocyte enhancer-binding protein 1
Search

AEBP1

0.95	AE binding protein 1

0.61	GO:0006508	proteolysis
0.61	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0051604	protein maturation
0.44	GO:0006518	peptide metabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.64	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.60	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.60	GO:0003714	transcription corepressor activity
0.51	GO:0004185	serine-type carboxypeptidase activity

0.61	GO:0005615	extracellular space
0.58	GO:0031012	extracellular matrix
0.35	GO:0005856	cytoskeleton

0.78

EC:3.4.17

GO:0004181

sp|Q8IUX8|EGFL6_HUMAN
Epidermal growth factor-like protein 6
Search

EGFL6

0.97	EGF like domain multiple 6

0.79	GO:0030198	extracellular matrix organization
0.58	GO:0010811	positive regulation of cell-substrate adhesion
0.43	GO:0030903	notochord development
0.42	GO:0008593	regulation of Notch signaling pathway
0.38	GO:0007155	cell adhesion
0.38	GO:0030154	cell differentiation
0.37	GO:0060347	heart trabecula formation
0.37	GO:0003171	atrioventricular valve development
0.35	GO:0010694	positive regulation of alkaline phosphatase activity
0.34	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus

0.69	GO:0005509	calcium ion binding
0.37	GO:0005178	integrin binding

0.56	GO:0005604	basement membrane
0.36	GO:0005615	extracellular space
0.35	GO:0034678	integrin alpha8-beta1 complex
0.34	GO:0030485	smooth muscle contractile fiber
0.33	GO:0005634	nucleus

sp|Q8IUY3|GRAM2_HUMAN
GRAM domain-containing protein 2
Search

GRAMD2A

0.89	LOW QUALITY PROTEIN: GRAM domain-containing protein 2

0.35	GO:0043547	positive regulation of GTPase activity
0.35	GO:0007018	microtubule-based movement
0.34	GO:0035556	intracellular signal transduction

0.41	GO:0042802	identical protein binding
0.35	GO:0005096	GTPase activator activity
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.35	GO:0003779	actin binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.44	GO:0005881	cytoplasmic microtubule
0.35	GO:0016459	myosin complex
0.30	GO:0016020	membrane

sp|Q8IUZ0|LRC49_HUMAN
Leucine-rich repeat-containing protein 49
Search

LRRC49

0.96	Tubulin polyglutamylase complex subunit 4

0.65	GO:0018095	protein polyglutamylation
0.47	GO:0060271	cilium assembly
0.45	GO:0022008	neurogenesis
0.45	GO:0007018	microtubule-based movement

0.45	GO:0003777	microtubule motor activity
0.45	GO:0008017	microtubule binding
0.40	GO:0016887	ATPase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:0015630	microtubule cytoskeleton
0.68	GO:0099513	polymeric cytoskeletal fiber
0.54	GO:0005829	cytosol
0.40	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0016887

sp|Q8IUZ5|AT2L2_HUMAN
5-phosphohydroxy-L-lysine phospho-lyase
Search

PHYKPL

0.93	ethanolamine-phosphate phospho-lyase

0.35	GO:0030574	collagen catabolic process
0.35	GO:0006554	lysine catabolic process
0.34	GO:0006646	phosphatidylethanolamine biosynthetic process

0.69	GO:0008483	transaminase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.52	GO:0042802	identical protein binding
0.48	GO:0016829	lyase activity

0.45	GO:0005739	mitochondrion
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.6.1

GO:0008483

sp|Q8IV01|SYT12_HUMAN
Synaptotagmin-12
Search

SYT12

0.95	Synaptotagmin XII

0.84	GO:0060291	long-term synaptic potentiation
0.84	GO:0046928	regulation of neurotransmitter secretion
0.52	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.51	GO:0017158	regulation of calcium ion-dependent exocytosis
0.50	GO:0006906	vesicle fusion
0.44	GO:0048792	spontaneous exocytosis of neurotransmitter
0.33	GO:0006659	phosphatidylserine biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:0010468	regulation of gene expression

0.53	GO:0005544	calcium-dependent phospholipid binding
0.50	GO:0019905	syntaxin binding
0.49	GO:0030276	clathrin binding
0.45	GO:0005509	calcium ion binding
0.32	GO:0043565	sequence-specific DNA binding

0.49	GO:0098793	presynapse
0.40	GO:0005886	plasma membrane
0.40	GO:0099501	exocytic vesicle membrane
0.38	GO:0030054	cell junction
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q8IV03|LUR1L_HUMAN
Leucine rich adaptor protein 1-like
Search

LURAP1L

0.93	Leucine rich adaptor protein 1 like

0.84	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.31	GO:0016310	phosphorylation

0.31

GO:0016301

kinase activity

sp|Q8IV04|TB10C_HUMAN
Carabin
Search

TBC1D10C

0.92

Carabin

0.84	GO:0051534	negative regulation of NFAT protein import into nucleus
0.80	GO:0050869	negative regulation of B cell activation
0.78	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.77	GO:0042147	retrograde transport, endosome to Golgi
0.65	GO:0031338	regulation of vesicle fusion
0.65	GO:0090630	activation of GTPase activity
0.54	GO:0006886	intracellular protein transport
0.47	GO:0097202	activation of cysteine-type endopeptidase activity
0.45	GO:1902017	regulation of cilium assembly
0.41	GO:0043312	neutrophil degranulation

0.62	GO:0017137	Rab GTPase binding
0.59	GO:0005096	GTPase activator activity
0.46	GO:0030165	PDZ domain binding
0.45	GO:0045296	cadherin binding
0.40	GO:0047730	carnosine synthase activity
0.36	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0016887	ATPase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0031527	filopodium membrane
0.66	GO:0005829	cytosol
0.54	GO:0012505	endomembrane system
0.39	GO:0031982	vesicle
0.38	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0005902	microvillus
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.35	GO:0044446	intracellular organelle part

0.40

EC:6.3.2.11

GO:0047730

sp|Q8IV08|PLD3_HUMAN
Phospholipase D3
Search

PLD3

0.92	Phospholipase D family member 3

0.41	GO:0016042	lipid catabolic process
0.32	GO:0006468	protein phosphorylation

0.45	GO:0004630	phospholipase D activity
0.45	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:3.1.4.4

GO:0004630

sp|Q8IV13|CCNJL_HUMAN
Cyclin-J-like protein
Search

CCNJL

0.87	Cyclin J like

0.33	GO:0006909	phagocytosis
0.33	GO:0001812	positive regulation of type I hypersensitivity
0.33	GO:0001805	positive regulation of type III hypersensitivity
0.33	GO:0032765	positive regulation of mast cell cytokine production
0.33	GO:0033026	negative regulation of mast cell apoptotic process
0.33	GO:0002894	positive regulation of type II hypersensitivity
0.33	GO:0001796	regulation of type IIa hypersensitivity
0.33	GO:0002554	serotonin secretion by platelet
0.33	GO:0050878	regulation of body fluid levels
0.33	GO:0007229	integrin-mediated signaling pathway

0.35	GO:0005515	protein binding
0.33	GO:0019767	IgE receptor activity
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0005198	structural molecule activity
0.32	GO:0004890	GABA-A receptor activity
0.32	GO:0001681	sialate O-acetylesterase activity
0.32	GO:0005230	extracellular ligand-gated ion channel activity
0.32	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.60	GO:0005634	nucleus
0.33	GO:0009897	external side of plasma membrane
0.33	GO:0032997	Fc receptor complex
0.33	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.33	GO:0030132	clathrin coat of coated pit
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0035866	alphav-beta3 integrin-PKCalpha complex
0.33	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0008275	gamma-tubulin small complex

0.32

EC:3.1.1.53

GO:0001681

sp|Q8IV16|HDBP1_HUMAN
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
Search

GPIHBP1

0.97	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

0.87	GO:0071503	response to heparin
0.87	GO:0051006	positive regulation of lipoprotein lipase activity
0.85	GO:0070328	triglyceride homeostasis
0.57	GO:0090321	positive regulation of chylomicron remnant clearance
0.56	GO:0034371	chylomicron remodeling
0.53	GO:0045056	transcytosis
0.52	GO:0006501	C-terminal protein lipidation
0.52	GO:0034394	protein localization to cell surface
0.51	GO:0001523	retinoid metabolic process
0.51	GO:0042632	cholesterol homeostasis

0.89	GO:0035478	chylomicron binding
0.87	GO:0035473	lipase binding
0.47	GO:0008320	protein transmembrane transporter activity
0.46	GO:0008289	lipid binding

0.86	GO:0031362	anchored component of external side of plasma membrane
0.52	GO:0034364	high-density lipoprotein particle
0.50	GO:0016323	basolateral plasma membrane
0.50	GO:0016324	apical plasma membrane
0.36	GO:0005622	intracellular

sp|Q8IV20|LACC1_HUMAN
Laccase domain-containing protein 1
Search

LACC1

0.97	Laccase domain-containing protein 1

0.72	GO:0005507	copper ion binding
0.40	GO:0005515	protein binding

0.55

GO:0042579

microbody

sp|Q8IV31|TM139_HUMAN
Transmembrane protein 139
Search

TMEM139

0.47	Transmembrane domain-containing protein (Fragment)

0.35

GO:0055114

oxidation-reduction process

0.38	GO:0015035	protein disulfide oxidoreductase activity
0.36	GO:0005515	protein binding
0.33	GO:0016740	transferase activity

0.30

GO:0044425

membrane part

0.33

EC:2

GO:0016740

sp|Q8IV32|CCD71_HUMAN
Coiled-coil domain-containing protein 71
Search

CCDC71

0.94	Coiled-coil domain-containing protein 71

0.53	GO:0045600	positive regulation of fat cell differentiation
0.44	GO:0044255	cellular lipid metabolic process
0.43	GO:0009405	pathogenesis

0.39

GO:0003723

RNA binding

0.30

GO:0031224

intrinsic component of membrane

sp|Q8IV33|K0825_HUMAN
Uncharacterized protein KIAA0825
Search

sp|Q8IV35|WDR49_HUMAN
WD repeat-containing protein 49
Search

WDR49

0.95	LOW QUALITY PROTEIN: WD repeat-containing protein 49

0.68

GO:0005509

calcium ion binding

sp|Q8IV36|HID1_HUMAN
Protein HID1
Search

HID1

0.97	HID1 domain containing b

0.85	GO:0031001	response to brefeldin A
0.66	GO:0006886	intracellular protein transport

0.36

GO:0005515

protein binding

0.83	GO:0000138	Golgi trans cisterna
0.82	GO:0005797	Golgi medial cisterna
0.80	GO:0090498	extrinsic component of Golgi membrane
0.75	GO:0005881	cytoplasmic microtubule
0.62	GO:0005829	cytosol
0.41	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q8IV38|ANKY2_HUMAN
Ankyrin repeat and MYND domain-containing protein 2
Search

ANKMY2

0.96	Ankyrin repeat and MYND domain-containing protein 2

0.70	GO:0008589	regulation of smoothened signaling pathway
0.35	GO:0008299	isoprenoid biosynthetic process

0.65	GO:0019899	enzyme binding
0.37	GO:0046872	metal ion binding
0.36	GO:0070567	cytidylyltransferase activity

0.44	GO:0005929	cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IV42|PSTK_HUMAN
L-seryl-tRNA(Sec) kinase
Search

PSTK

0.96	Phosphoseryl-tRNA kinase

0.61	GO:0001514	selenocysteine incorporation
0.57	GO:0016310	phosphorylation
0.40	GO:0097056	selenocysteinyl-tRNA(Sec) biosynthetic process

0.60	GO:0016301	kinase activity
0.54	GO:0000049	tRNA binding
0.39	GO:0098620	seryl-selenocysteinyl-tRNA kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q8IV45|UN5CL_HUMAN
UNC5C-like protein
Search

sp|Q8IV48|ERI1_HUMAN
3'-5' exoribonuclease 1
Search

ERI1

0.97	Exoribonuclease 1

0.45	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.39	GO:0071044	histone mRNA catabolic process
0.39	GO:0006259	DNA metabolic process
0.39	GO:0031125	rRNA 3'-end processing
0.38	GO:0031047	gene silencing by RNA

0.50	GO:0003676	nucleic acid binding
0.49	GO:0008408	3'-5' exonuclease activity
0.37	GO:0043022	ribosome binding
0.35	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters
0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.50	GO:0005730	nucleolus
0.40	GO:0071204	histone pre-mRNA 3'end processing complex
0.39	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

0.35

EC:3.1.13

GO:0016896

sp|Q8IV50|LYSM2_HUMAN
LysM and putative peptidoglycan-binding domain-containing protein 2
Search

LYSMD2

0.94	LysM and peptidoglycan-binding domain-containing protein 2

0.43	GO:0006368	transcription elongation from RNA polymerase II promoter
0.41	GO:0016570	histone modification

0.36

GO:0005515

protein binding

0.67	GO:0005654	nucleoplasm
0.42	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.38	GO:0043234	protein complex

sp|Q8IV53|DEN1C_HUMAN
DENN domain-containing protein 1C
Search

DENND1C

0.95	LOW QUALITY PROTEIN: DENN domain-containing protein 1C

0.66	GO:0065009	regulation of molecular function
0.56	GO:0032456	endocytic recycling
0.55	GO:0032483	regulation of Rab protein signal transduction
0.54	GO:0048488	synaptic vesicle endocytosis
0.45	GO:0035745	T-helper 2 cell cytokine production
0.44	GO:0050852	T cell receptor signaling pathway
0.35	GO:0015031	protein transport
0.33	GO:0055085	transmembrane transport

0.84	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.53	GO:0032266	phosphatidylinositol-3-phosphate binding
0.51	GO:0017124	SH3 domain binding
0.35	GO:0005509	calcium ion binding

0.55	GO:0030136	clathrin-coated vesicle
0.51	GO:0043025	neuronal cell body
0.51	GO:0030425	dendrite
0.51	GO:0005829	cytosol
0.50	GO:0030662	coated vesicle membrane
0.49	GO:0045202	synapse
0.49	GO:0005654	nucleoplasm
0.37	GO:0098590	plasma membrane region
0.37	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|Q8IV56|PRR15_HUMAN
Proline-rich protein 15
Search

PRR15

0.97	Proline-rich protein 15

0.70

GO:0007275

multicellular organism development

sp|Q8IV61|GRP3_HUMAN
Ras guanyl-releasing protein 3
Search

RASGRP3

0.94	Ras guanyl-releasing protein 3

0.81	GO:0007265	Ras protein signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.35	GO:0071277	cellular response to calcium ion
0.35	GO:0007268	chemical synaptic transmission
0.35	GO:0000165	MAPK cascade
0.32	GO:0005975	carbohydrate metabolic process

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.75	GO:0005096	GTPase activator activity
0.69	GO:0005509	calcium ion binding
0.51	GO:0019900	kinase binding
0.50	GO:0017016	Ras GTPase binding
0.37	GO:0019992	diacylglycerol binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.33	GO:0102499	SHG alpha-glucan phosphorylase activity
0.33	GO:0008184	glycogen phosphorylase activity

0.55	GO:0032045	guanyl-nucleotide exchange factor complex
0.52	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IV63|VRK3_HUMAN
Inactive serine/threonine-protein kinase VRK3
Search

VRK3

0.97	Inactive serine-threonine-protein kinase VRK3

0.63	GO:0006468	protein phosphorylation
0.55	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.54	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.47	GO:0018209	peptidyl-serine modification
0.43	GO:0008360	regulation of cell shape
0.34	GO:2000659	regulation of interleukin-1-mediated signaling pathway
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0034599	cellular response to oxidative stress
0.33	GO:0006355	regulation of transcription, DNA-templated
0.33	GO:0010467	gene expression

0.63	GO:0004672	protein kinase activity
0.55	GO:0019903	protein phosphatase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0019901	protein kinase binding
0.33	GO:0019904	protein domain specific binding
0.33	GO:0003676	nucleic acid binding

0.52	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.32	GO:0031967	organelle envelope
0.32	GO:0031090	organelle membrane
0.32	GO:0043234	protein complex
0.30	GO:0044425	membrane part

sp|Q8IV76|PASD1_HUMAN
Circadian clock protein PASD1
Search

PASD1

0.96	PAS domain containing repressor 1

0.67	GO:0042754	negative regulation of circadian rhythm
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0051253	negative regulation of RNA metabolic process
0.55	GO:0010558	negative regulation of macromolecule biosynthetic process
0.55	GO:0031327	negative regulation of cellular biosynthetic process
0.39	GO:0006351	transcription, DNA-templated

0.67	GO:0001223	transcription coactivator binding
0.43	GO:0046983	protein dimerization activity
0.40	GO:0003700	DNA binding transcription factor activity
0.37	GO:0003677	DNA binding

0.72	GO:1990512	Cry-Per complex
0.61	GO:0016607	nuclear speck
0.45	GO:0005667	transcription factor complex
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q8IV77|CNGA4_HUMAN
Cyclic nucleotide-gated cation channel alpha-4
Search

CNGA4

0.89	Cyclic nucleotide-gated channel cone photoreceptor subunit alpha

0.60	GO:0007600	sensory perception
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0071804	cellular potassium ion transport
0.46	GO:0042391	regulation of membrane potential
0.35	GO:0050896	response to stimulus
0.35	GO:0051290	protein heterotetramerization
0.35	GO:0051480	regulation of cytosolic calcium ion concentration
0.34	GO:0051283	negative regulation of sequestering of calcium ion
0.33	GO:0060401	cytosolic calcium ion transport
0.33	GO:0007283	spermatogenesis

0.70	GO:0005216	ion channel activity
0.66	GO:0022836	gated channel activity
0.59	GO:0015079	potassium ion transmembrane transporter activity
0.42	GO:0030553	cGMP binding
0.38	GO:0030552	cAMP binding
0.34	GO:0015054	gastrin receptor activity
0.33	GO:0015085	calcium ion transmembrane transporter activity
0.32	GO:0019904	protein domain specific binding

0.42	GO:0060170	ciliary membrane
0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0001750	photoreceptor outer segment
0.37	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.35	GO:0043204	perikaryon
0.34	GO:0030660	Golgi-associated vesicle membrane
0.34	GO:0000139	Golgi membrane
0.34	GO:0043195	terminal bouton

sp|Q8IVA1|PCP2_HUMAN
Purkinje cell protein 2 homolog
Search

PCP2

0.97	Purkinje cell-specific protein 2

0.69	GO:0050790	regulation of catalytic activity
0.42	GO:0016056	rhodopsin mediated signaling pathway
0.34	GO:0060259	regulation of feeding behavior
0.33	GO:0044093	positive regulation of molecular function

0.76	GO:0030695	GTPase regulator activity
0.39	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0001965	G-protein alpha-subunit binding
0.33	GO:0008047	enzyme activator activity

0.40	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|Q8IVB4|SL9A9_HUMAN
Sodium/hydrogen exchanger 9
Search

SLC9A9

0.60	Sodium/hydrogen exchanger

0.78	GO:0006885	regulation of pH
0.76	GO:0035725	sodium ion transmembrane transport
0.62	GO:1902600	hydrogen ion transmembrane transport
0.52	GO:0099587	inorganic ion import across plasma membrane
0.50	GO:0030004	cellular monovalent inorganic cation homeostasis
0.47	GO:0071805	potassium ion transmembrane transport
0.43	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway
0.43	GO:0097484	dendrite extension
0.43	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway
0.42	GO:0060996	dendritic spine development

0.81	GO:0015385	sodium:proton antiporter activity
0.52	GO:0015386	potassium:proton antiporter activity
0.33	GO:0005515	protein binding

0.60	GO:0055037	recycling endosome
0.43	GO:0044308	axonal spine
0.42	GO:0005770	late endosome
0.42	GO:0010008	endosome membrane
0.41	GO:0043679	axon terminus
0.41	GO:0005886	plasma membrane
0.41	GO:0030425	dendrite
0.41	GO:0005769	early endosome
0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0005739	mitochondrion

sp|Q8IVB5|LIX1L_HUMAN
LIX1-like protein
Search

LIX1L

0.97	Limb and CNS expressed 1 like

0.85

GO:0097352

autophagosome maturation

0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IVC4|ZN584_HUMAN
Zinc finger protein 584
Search

0.71	Zinc finger protein 584

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.36	GO:0010467	gene expression
0.36	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043043	peptide biosynthetic process
0.35	GO:1902466	positive regulation of histone H3-K27 trimethylation
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:1900114	positive regulation of histone H3-K9 trimethylation
0.35	GO:0035562	negative regulation of chromatin binding

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.36	GO:0003735	structural constituent of ribosome
0.34	GO:1990841	promoter-specific chromatin binding
0.33	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.36	GO:1990904	ribonucleoprotein complex
0.36	GO:0043226	organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IVD9|NUDC3_HUMAN
NudC domain-containing protein 3
Search

NUDCD3

0.97	NudC domain-containing protein 3

0.86	GO:1905793	protein localization to pericentriolar material
0.77	GO:0060271	cilium assembly
0.54	GO:0006457	protein folding
0.53	GO:0032502	developmental process

0.55

GO:0051082

unfolded protein binding

0.80	GO:0005868	cytoplasmic dynein complex
0.42	GO:0005737	cytoplasm

sp|Q8IVE0|CROL2_HUMAN
Putative ciliary rootlet coiled-coil protein-like 2 protein
Search

0.11	Putative ciliary rootlet coiled-coil protein-like 2 protein

0.82	GO:0007098	centrosome cycle
0.69	GO:1903566	positive regulation of protein localization to cilium
0.66	GO:0032053	ciliary basal body organization
0.65	GO:0045724	positive regulation of cilium assembly
0.64	GO:0010669	epithelial structure maintenance
0.63	GO:0045494	photoreceptor cell maintenance
0.58	GO:0051656	establishment of organelle localization
0.56	GO:0033365	protein localization to organelle
0.33	GO:0007062	sister chromatid cohesion
0.33	GO:0030261	chromosome condensation

0.62	GO:0019894	kinesin binding
0.56	GO:0003779	actin binding
0.49	GO:0005198	structural molecule activity
0.33	GO:0003774	motor activity
0.33	GO:0030276	clathrin binding
0.33	GO:0005543	phospholipid binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0046914	transition metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding

0.86	GO:0035253	ciliary rootlet
0.63	GO:0001917	photoreceptor inner segment
0.62	GO:0005814	centriole
0.60	GO:0005813	centrosome
0.57	GO:0015629	actin cytoskeleton
0.54	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane
0.42	GO:0070062	extracellular exosome
0.34	GO:0005882	intermediate filament
0.32	GO:0005694	chromosome

sp|Q8IVE3|PKHH2_HUMAN
Pleckstrin homology domain-containing family H member 2
Search

PLEKHH2

0.96	Pleckstrin like proteiny domain-containing family H member 2

0.57	GO:0030835	negative regulation of actin filament depolymerization
0.34	GO:0001569	branching involved in blood vessel morphogenesis
0.34	GO:0007411	axon guidance
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.53	GO:0042802	identical protein binding
0.53	GO:0003779	actin binding
0.34	GO:0046983	protein dimerization activity
0.33	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.69	GO:0005856	cytoskeleton
0.57	GO:0030027	lamellipodium
0.54	GO:0016604	nuclear body
0.54	GO:0044448	cell cortex part
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane

sp|Q8IVF1|NTM2A_HUMAN
NUT family member 2A
Search

0.68	NUT midline carcinoma family member 1

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|Q8IVF2|AHNK2_HUMAN
Protein AHNAK2
Search

0.11	AHNAK nucleoprotein 2

0.72	GO:1901385	regulation of voltage-gated calcium channel activity
0.61	GO:0043484	regulation of RNA splicing
0.55	GO:0051259	protein oligomerization
0.52	GO:0001778	plasma membrane repair

0.72	GO:0044548	S100 protein binding
0.68	GO:0045296	cadherin binding
0.66	GO:0097493	structural molecule activity conferring elasticity

0.74	GO:0042383	sarcolemma
0.71	GO:0043034	costamere
0.71	GO:0044291	cell-cell contact zone
0.67	GO:0070062	extracellular exosome
0.67	GO:0045121	membrane raft
0.66	GO:0005829	cytosol
0.62	GO:0015629	actin cytoskeleton
0.49	GO:0030018	Z disc
0.49	GO:0005634	nucleus
0.47	GO:0030659	cytoplasmic vesicle membrane

sp|Q8IVF4|DYH10_HUMAN
Dynein heavy chain 10, axonemal
Search

DNAH10

0.85	Dynein axonemal heavy chain 10

0.74	GO:0007018	microtubule-based movement
0.33	GO:0060271	cilium assembly
0.33	GO:0015991	ATP hydrolysis coupled proton transport
0.33	GO:0006289	nucleotide-excision repair
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:0010468	regulation of gene expression
0.31	GO:0006508	proteolysis

0.75	GO:0003777	microtubule motor activity
0.57	GO:0016887	ATPase activity
0.56	GO:0045503	dynein light chain binding
0.56	GO:0051959	dynein light intermediate chain binding
0.56	GO:0045505	dynein intermediate chain binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0015078	hydrogen ion transmembrane transporter activity
0.31	GO:0070001	aspartic-type peptidase activity

0.77	GO:0030286	dynein complex
0.40	GO:0005929	cilium
0.37	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.36	GO:0005874	microtubule
0.33	GO:0000439	core TFIIH complex
0.33	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.30	GO:0031224	intrinsic component of membrane

0.57

GO:0016887

sp|Q8IVF5|TIAM2_HUMAN
T-lymphoma invasion and metastasis-inducing protein 2
Search

TIAM2

0.89	T-lymphoma invasion and metastasis-inducing protein 2

0.76	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.61	GO:0035556	intracellular signal transduction
0.37	GO:0019216	regulation of lipid metabolic process
0.37	GO:0043065	positive regulation of apoptotic process
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.71	GO:0005057	signal transducer activity, downstream of receptor
0.50	GO:0005096	GTPase activator activity

0.44	GO:0005622	intracellular
0.39	GO:0070062	extracellular exosome
0.39	GO:0030175	filopodium
0.39	GO:0030426	growth cone
0.39	GO:0030027	lamellipodium
0.30	GO:0016020	membrane

sp|Q8IVF6|AN18A_HUMAN
Ankyrin repeat domain-containing protein 18A
Search

ANKRD18A

0.97	Ankyrin repeat domain-containing protein 18A

0.42	GO:0031648	protein destabilization
0.41	GO:0031122	cytoplasmic microtubule organization
0.41	GO:0065009	regulation of molecular function
0.41	GO:0031098	stress-activated protein kinase signaling cascade
0.41	GO:0030705	cytoskeleton-dependent intracellular transport
0.40	GO:0051260	protein homooligomerization
0.40	GO:0016055	Wnt signaling pathway
0.39	GO:0060255	regulation of macromolecule metabolic process
0.39	GO:0031323	regulation of cellular metabolic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process

0.46	GO:0008200	ion channel inhibitor activity
0.42	GO:0005515	protein binding
0.39	GO:0003700	DNA binding transcription factor activity
0.37	GO:0003677	DNA binding

0.51	GO:0070062	extracellular exosome
0.43	GO:0005634	nucleus
0.42	GO:0005813	centrosome
0.39	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q8IVF7|FMNL3_HUMAN
Formin-like protein 3
Search

FMNL3

0.88	Formin like 3

0.73	GO:0030036	actin cytoskeleton organization
0.73	GO:0016477	cell migration
0.69	GO:0022604	regulation of cell morphogenesis
0.60	GO:0065008	regulation of biological quality
0.46	GO:0030865	cortical cytoskeleton organization

0.77	GO:0017048	Rho GTPase binding
0.74	GO:0003779	actin binding
0.66	GO:0032794	GTPase activating protein binding
0.45	GO:0045296	cadherin binding

0.55	GO:0005794	Golgi apparatus
0.53	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane

sp|Q8IVG5|SAM9L_HUMAN
Sterile alpha motif domain-containing protein 9-like
Search

SAMD9L

0.94	LOW QUALITY PROTEIN: sterile alpha motif domain-containing protein 9

0.80	GO:0034058	endosomal vesicle fusion
0.45	GO:0035726	common myeloid progenitor cell proliferation
0.44	GO:0048536	spleen development
0.44	GO:0017145	stem cell division
0.43	GO:0002244	hematopoietic progenitor cell differentiation
0.42	GO:0042176	regulation of protein catabolic process
0.35	GO:0006397	mRNA processing
0.35	GO:0090501	RNA phosphodiester bond hydrolysis
0.34	GO:0006468	protein phosphorylation

0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005515	protein binding
0.35	GO:0004540	ribonuclease activity
0.35	GO:0003677	DNA binding
0.34	GO:0004672	protein kinase activity

0.65	GO:0005769	early endosome
0.56	GO:0005829	cytosol
0.47	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q8IVG9|HUNIN_HUMAN
Humanin
Search

0.56

Humanin

0.86	GO:1900116	extracellular negative regulation of signal transduction
0.84	GO:0030595	leukocyte chemotaxis
0.78	GO:0043066	negative regulation of apoptotic process
0.77	GO:0006915	apoptotic process
0.76	GO:0006879	cellular iron ion homeostasis
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.86

GO:0048019

receptor antagonist activity

0.79	GO:0048471	perinuclear region of cytoplasm
0.66	GO:0005576	extracellular region
0.60	GO:0005739	mitochondrion

sp|Q8IVH2|FOXP4_HUMAN
Forkhead box protein P4
Search

FOXP4

0.97	Forkhead box protein P4

0.56	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0006351	transcription, DNA-templated
0.44	GO:0030154	cell differentiation
0.44	GO:0009653	anatomical structure morphogenesis
0.42	GO:1901250	negative regulation of lung goblet cell differentiation
0.41	GO:0060428	lung epithelium development
0.39	GO:0007507	heart development
0.39	GO:0009790	embryo development
0.39	GO:1903507	negative regulation of nucleic acid-templated transcription
0.38	GO:2000113	negative regulation of cellular macromolecule biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.35	GO:0003682	chromatin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0043621	protein self-association

0.61	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|Q8IVH4|MMAA_HUMAN
Methylmalonic aciduria type A protein, mitochondrial
Search

MMAA

0.96	Methylmalonic aciduria type A protein, mitochondrial

0.37	GO:0009236	cobalamin biosynthetic process
0.36	GO:0019626	short-chain fatty acid catabolic process

0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.56	GO:0042803	protein homodimerization activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IVH8|M4K3_HUMAN
Mitogen-activated protein kinase kinase kinase kinase 3
Search

MAP4K3

0.82	Mitogen-activated protein kinase kinase kinase kinase

0.85	GO:0000185	activation of MAPKKK activity
0.78	GO:0000165	MAPK cascade
0.56	GO:0034612	response to tumor necrosis factor
0.55	GO:0009411	response to UV
0.48	GO:0031098	stress-activated protein kinase signaling cascade
0.46	GO:0007346	regulation of mitotic cell cycle
0.45	GO:0042981	regulation of apoptotic process

0.85	GO:0008349	MAP kinase kinase kinase kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.85

GO:0008349

sp|Q8IVI9|NOSTN_HUMAN
Nostrin
Search

NOSTRIN

0.93	Nitric oxide synthase trafficking

0.66	GO:0045892	negative regulation of transcription, DNA-templated
0.54	GO:0072011	glomerular endothelium development
0.52	GO:0072015	glomerular visceral epithelial cell development
0.52	GO:0097205	renal filtration
0.51	GO:0051489	regulation of filopodium assembly
0.51	GO:0002040	sprouting angiogenesis
0.47	GO:0006897	endocytosis
0.43	GO:0050999	regulation of nitric-oxide synthase activity
0.34	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0035556	intracellular signal transduction

0.52	GO:0003677	DNA binding
0.40	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0098772	molecular function regulator
0.33	GO:0004435	phosphatidylinositol phospholipase C activity
0.32	GO:0004871	signal transducer activity

0.74	GO:0016607	nuclear speck
0.47	GO:0031410	cytoplasmic vesicle
0.46	GO:0005856	cytoskeleton
0.40	GO:0005886	plasma membrane
0.40	GO:0012506	vesicle membrane
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:3.1.4.11	GO:0004435
0.33	KEGG:R03435	GO:0004435

sp|Q8IVJ1|S41A1_HUMAN
Solute carrier family 41 member 1
Search

SLC41A1

0.94	Solute carrier family 41 (magnesium transporter), member 1

0.61	GO:0098655	cation transmembrane transport
0.61	GO:0071286	cellular response to magnesium ion
0.59	GO:0010961	cellular magnesium ion homeostasis
0.53	GO:0015693	magnesium ion transport
0.51	GO:0006814	sodium ion transport
0.46	GO:0098660	inorganic ion transmembrane transport
0.44	GO:0048793	pronephros development
0.42	GO:0043009	chordate embryonic development

0.62	GO:0061768	magnesium:sodium antiporter activity
0.54	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.53	GO:0015095	magnesium ion transmembrane transporter activity
0.33	GO:0003924	GTPase activity
0.33	GO:0001883	purine nucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0032549	ribonucleoside binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0016323	basolateral plasma membrane
0.44	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q8IVJ8|APRG1_HUMAN
AP20 region protein 1
Search

0.30	AP20 region protein 1

0.30

GO:0044425

membrane part

sp|Q8IVK1|GLCM1_HUMAN
Putative glycosylation-dependent cell adhesion molecule 1
Search

0.37	Putative glycosylation-dependent cell adhesion molecule 1

0.72

GO:0050776

regulation of immune response

0.55

GO:0005886

plasma membrane

sp|Q8IVL0|NAV3_HUMAN
Neuron navigator 3
Search

NAV3

0.96	Neuron navigator 3

0.59	GO:1905929	positive regulation of invadopodium disassembly
0.56	GO:0032703	negative regulation of interleukin-2 production
0.55	GO:0007026	negative regulation of microtubule depolymerization
0.55	GO:0031116	positive regulation of microtubule polymerization
0.53	GO:0030336	negative regulation of cell migration
0.34	GO:0072576	liver morphogenesis
0.33	GO:0031016	pancreas development

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0008017	microtubule binding
0.33	GO:0003779	actin binding

0.55	GO:1990752	microtubule end
0.38	GO:0005640	nuclear outer membrane
0.33	GO:0030175	filopodium
0.33	GO:0030027	lamellipodium
0.33	GO:0005794	Golgi apparatus

sp|Q8IVL1|NAV2_HUMAN
Neuron navigator 2
Search

0.87	Neuron navigator 2

0.72	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback
0.71	GO:0021564	vagus nerve development
0.71	GO:0021563	glossopharyngeal nerve development
0.69	GO:0021554	optic nerve development
0.64	GO:0007605	sensory perception of sound
0.64	GO:0007626	locomotory behavior
0.60	GO:0007608	sensory perception of smell

0.64	GO:0008201	heparin binding
0.48	GO:0032559	adenyl ribonucleotide binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004386	helicase activity
0.39	GO:0005515	protein binding
0.36	GO:0004427	inorganic diphosphatase activity

0.69	GO:0005614	interstitial matrix
0.59	GO:0005654	nucleoplasm

0.36	EC:3.6.1.1	GO:0004427
0.36	KEGG:R00004	GO:0004427

sp|Q8IVL5|P3H2_HUMAN
Prolyl 3-hydroxylase 2
Search

P3H2

0.97	Prolyl 3-hydroxylase 2

0.60	GO:0018126	protein hydroxylation
0.59	GO:0032963	collagen metabolic process
0.54	GO:0008285	negative regulation of cell proliferation
0.52	GO:0018208	peptidyl-proline modification
0.52	GO:0055114	oxidation-reduction process
0.45	GO:1901874	negative regulation of post-translational protein modification
0.43	GO:0060348	bone development
0.42	GO:0050821	protein stabilization
0.42	GO:0050708	regulation of protein secretion
0.40	GO:0006457	protein folding

0.77	GO:0031418	L-ascorbic acid binding
0.67	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.61	GO:0005506	iron ion binding
0.51	GO:0051213	dioxygenase activity
0.44	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0005518	collagen binding

0.56	GO:0005604	basement membrane
0.52	GO:0005783	endoplasmic reticulum
0.50	GO:0005794	Golgi apparatus
0.41	GO:0016528	sarcoplasm
0.35	GO:0070062	extracellular exosome
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005634	nucleus
0.33	GO:0032991	macromolecular complex
0.32	GO:0005886	plasma membrane

0.67

GO:0016705

sp|Q8IVL6|P3H3_HUMAN
Prolyl 3-hydroxylase 3
Search

P3H3

0.91	Prolyl 3-hydroxylase 3

0.64	GO:0032963	collagen metabolic process
0.64	GO:0017185	peptidyl-lysine hydroxylation
0.58	GO:0008285	negative regulation of cell proliferation
0.52	GO:0019511	peptidyl-proline hydroxylation
0.51	GO:0055114	oxidation-reduction process
0.43	GO:0009059	macromolecule biosynthetic process
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:1901874	negative regulation of post-translational protein modification
0.35	GO:0060348	bone development
0.34	GO:0050821	protein stabilization

0.76	GO:0031418	L-ascorbic acid binding
0.66	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.61	GO:0005506	iron ion binding
0.46	GO:0051213	dioxygenase activity
0.41	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005515	protein binding

0.48	GO:1902494	catalytic complex
0.46	GO:0005783	endoplasmic reticulum
0.38	GO:0005604	basement membrane
0.37	GO:0005794	Golgi apparatus
0.34	GO:0016528	sarcoplasm
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.66

GO:0016705

sp|Q8IVL8|CBPO_HUMAN
Carboxypeptidase O
Search

CPO

0.97	Carboxypeptidase O

0.60	GO:0006508	proteolysis
0.42	GO:0002002	regulation of angiotensin levels in blood
0.34	GO:0042730	fibrinolysis

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding

0.56	GO:0046658	anchored component of plasma membrane
0.46	GO:0044421	extracellular region part
0.38	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.76

EC:3.4.17

GO:0004181

sp|Q8IVM0|CCD50_HUMAN
Coiled-coil domain-containing protein 50
Search

CCDC50

0.96	Coiled-coil domain-containing protein 50

0.81

GO:0007605

sensory perception of sound

0.79

GO:0031625

ubiquitin protein ligase binding

0.68	GO:0005829	cytosol
0.59	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IVM7|CM029_HUMAN
Putative uncharacterized protein encoded by LINC00346
Search

sp|Q8IVM8|S22A9_HUMAN
Solute carrier family 22 member 9
Search

0.97	Solute carrier family 22 member 9

0.60	GO:0043252	sodium-independent organic anion transport
0.60	GO:0015747	urate transport
0.54	GO:0055085	transmembrane transport
0.51	GO:0015913	short-chain fatty acid import
0.49	GO:0015698	inorganic anion transport
0.46	GO:0009914	hormone transport
0.39	GO:1901998	toxin transport
0.36	GO:0046415	urate metabolic process

0.60	GO:0015143	urate transmembrane transporter activity
0.60	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.55	GO:0005452	inorganic anion exchanger activity
0.51	GO:0015636	short-chain fatty acid transmembrane transporter activity
0.46	GO:0015301	anion:anion antiporter activity
0.39	GO:0019534	toxin transmembrane transporter activity

0.48	GO:0005887	integral component of plasma membrane
0.46	GO:0016323	basolateral plasma membrane
0.38	GO:0016324	apical plasma membrane
0.35	GO:0009897	external side of plasma membrane

sp|Q8IVN3|MSTN1_HUMAN
Musculoskeletal embryonic nuclear protein 1
Search

MUSTN1

0.97	Musculoskeletal embryonic nuclear protein 1

0.86	GO:0035988	chondrocyte proliferation
0.85	GO:0002062	chondrocyte differentiation
0.85	GO:0042246	tissue regeneration
0.49	GO:1902730	positive regulation of proteoglycan biosynthetic process
0.49	GO:1902732	positive regulation of chondrocyte proliferation
0.48	GO:0032332	positive regulation of chondrocyte differentiation
0.43	GO:0010628	positive regulation of gene expression
0.40	GO:0030326	embryonic limb morphogenesis

0.61	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part

sp|Q8IVN8|SBSPO_HUMAN
Somatomedin-B and thrombospondin type-1 domain-containing protein
Search

SBSPON

0.96	Somatomedin B and thrombospondin type 1 domain containing

0.73	GO:0006955	immune response
0.71	GO:0006898	receptor-mediated endocytosis
0.35	GO:0050778	positive regulation of immune response
0.35	GO:0072376	protein activation cascade
0.35	GO:0002252	immune effector process
0.33	GO:0010951	negative regulation of endopeptidase activity
0.33	GO:0010935	regulation of macrophage cytokine production
0.33	GO:0032760	positive regulation of tumor necrosis factor production
0.33	GO:0032755	positive regulation of interleukin-6 production
0.33	GO:0006952	defense response

0.80	GO:0005044	scavenger receptor activity
0.77	GO:0001871	pattern binding
0.69	GO:0030246	carbohydrate binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.33	GO:0003823	antigen binding
0.33	GO:0001530	lipopolysaccharide binding
0.32	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.32	GO:0005509	calcium ion binding

0.60	GO:0031012	extracellular matrix
0.35	GO:0005579	membrane attack complex
0.32	GO:0005615	extracellular space

0.33

EC:2.4.1.69

GO:0008107

sp|Q8IVP5|FUND1_HUMAN
FUN14 domain-containing protein 1
Search

FUNDC1

0.96	FUN14 domain-containing protein 1

0.81	GO:0061726	mitochondrion disassembly
0.74	GO:0006914	autophagy
0.73	GO:0001666	response to hypoxia
0.42	GO:0010243	response to organonitrogen compound

0.37

GO:0005515

protein binding

0.79	GO:0031307	integral component of mitochondrial outer membrane
0.34	GO:0005634	nucleus

sp|Q8IVP9|ZN547_HUMAN
Zinc finger protein 547
Search

ZNF416

0.84	Zinc finger protein 416

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.35	GO:0006468	protein phosphorylation
0.34	GO:1902679	negative regulation of RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|Q8IVQ6|ZDH21_HUMAN
Palmitoyltransferase ZDHHC21
Search

ZDHHC21

0.55	Palmitoyltransferase

0.65	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.64	GO:0048733	sebaceous gland development
0.62	GO:0018345	protein palmitoylation
0.59	GO:0001942	hair follicle development
0.36	GO:0050999	regulation of nitric-oxide synthase activity

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.36	GO:0004792	thiosulfate sulfurtransferase activity

0.53	GO:0005794	Golgi apparatus
0.45	GO:0005886	plasma membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.32	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:2.3.1.225	GO:0019706
0.36	KEGG:R01931	GO:0004792

sp|Q8IVS2|FABD_HUMAN
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
Search

MCAT

0.44	Malonyl-CoA-acyl carrier protein transacylase

0.63	GO:0042967	acyl-carrier-protein biosynthetic process
0.52	GO:0006633	fatty acid biosynthetic process
0.35	GO:0006635	fatty acid beta-oxidation
0.35	GO:0005975	carbohydrate metabolic process
0.31	GO:0055085	transmembrane transport

0.57	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0003723	RNA binding
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.57

EC:2.3.1.39

GO:0004314

sp|Q8IVS8|GLCTK_HUMAN
Glycerate kinase
Search

GLYCTK

0.50	Glycerate kinase

0.56	GO:0016310	phosphorylation
0.48	GO:0036211	protein modification process
0.45	GO:0044267	cellular protein metabolic process
0.38	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
0.36	GO:0003341	cilium movement

0.60	GO:0008887	glycerate kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003777	microtubule motor activity
0.34	GO:0005515	protein binding
0.33	GO:0016887	ATPase activity

0.53	GO:0005794	Golgi apparatus
0.51	GO:0005829	cytosol
0.36	GO:0005858	axonemal dynein complex
0.36	GO:0005739	mitochondrion
0.33	GO:0005581	collagen trimer

0.60	EC:2.7.1.31	GO:0008887
0.60	KEGG:R01514	GO:0008887

sp|Q8IVT2|MISP_HUMAN
Mitotic interactor and substrate of PLK1
Search

MISP

0.96	Mitotic spindle positioning

0.46	GO:0051301	cell division
0.46	GO:0007049	cell cycle
0.38	GO:0006397	mRNA processing
0.32	GO:0008360	regulation of cell shape

0.48	GO:0003779	actin binding
0.36	GO:0003723	RNA binding

0.81	GO:0005925	focal adhesion
0.55	GO:0043231	intracellular membrane-bounded organelle
0.54	GO:0071944	cell periphery
0.49	GO:0099568	cytoplasmic region
0.46	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

sp|Q8IVT5|KSR1_HUMAN
Kinase suppressor of Ras 1
Search

KSR1

0.93	Kinase suppressor of Ras 1

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.58	GO:0043410	positive regulation of MAPK cascade

0.64	GO:0004672	protein kinase activity
0.62	GO:0031434	mitogen-activated protein kinase kinase binding
0.62	GO:0005078	MAP-kinase scaffold activity
0.62	GO:0071889	14-3-3 protein binding
0.61	GO:0051879	Hsp90 protein binding
0.58	GO:0008022	protein C-terminus binding
0.55	GO:0051087	chaperone binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005783	endoplasmic reticulum
0.46	GO:0043234	protein complex
0.38	GO:0032587	ruffle membrane
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q8IVU1|IGDC3_HUMAN
Immunoglobulin superfamily DCC subclass member 3
Search

IGDCC3

0.80	Neural cell adhesion molecule 1

0.59	GO:0050885	neuromuscular process controlling balance
0.50	GO:0007275	multicellular organism development
0.40	GO:0038007	netrin-activated signaling pathway
0.39	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.39	GO:0000904	cell morphogenesis involved in differentiation
0.39	GO:0006915	apoptotic process
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.38	GO:0006935	chemotaxis
0.37	GO:0006928	movement of cell or subcellular component
0.33	GO:0045663	positive regulation of myoblast differentiation

0.40	GO:0005042	netrin receptor activity
0.32	GO:0042802	identical protein binding

0.49

GO:0005887

integral component of plasma membrane

sp|Q8IVU3|HERC6_HUMAN
Probable E3 ubiquitin-protein ligase HERC6
Search

HERC6

0.94	HECT and RLD domain containing E3 ubiquitin protein ligase 5

0.73	GO:0016567	protein ubiquitination
0.57	GO:0032020	ISG15-protein conjugation
0.54	GO:0050688	regulation of defense response to virus
0.46	GO:0002244	hematopoietic progenitor cell differentiation

0.74	GO:0004842	ubiquitin-protein transferase activity
0.57	GO:0042296	ISG15 transferase activity
0.54	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0016874	ligase activity

0.57	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.34	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

sp|Q8IVU9|CJ107_HUMAN
Uncharacterized protein C10orf107
Search

CABCOCO1

0.92	Ciliary-associated calcium-binding coiled-coil protein 1

0.40	GO:0015074	DNA integration
0.38	GO:0006508	proteolysis

0.62	GO:0005509	calcium ion binding
0.41	GO:0070001	aspartic-type peptidase activity
0.39	GO:0004175	endopeptidase activity
0.36	GO:0003676	nucleic acid binding

0.74	GO:0036126	sperm flagellum
0.69	GO:0005813	centrosome
0.46	GO:0005737	cytoplasm
0.38	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IVV2|LOXH1_HUMAN
Lipoxygenase homology domain-containing protein 1
Search

0.54	Lipoxygenase homology domain-containing protein 1

0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.46	GO:0050982	detection of mechanical stimulus
0.43	GO:0070588	calcium ion transmembrane transport
0.43	GO:0007605	sensory perception of sound

0.77	GO:0004096	catalase activity
0.63	GO:0020037	heme binding
0.44	GO:0005262	calcium channel activity

0.44	GO:0032420	stereocilium
0.30	GO:0016020	membrane

0.77

EC:1.11.1.6

GO:0004096

sp|Q8IVV7|GID4_HUMAN
Glucose-induced degradation protein 4 homolog
Search

GID4

0.97	GID complex subunit 4

0.78	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination

0.76

GO:0061630

ubiquitin protein ligase activity

sp|Q8IVV8|NKAI4_HUMAN
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4
Search

NKAIN4

0.97	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4

0.50

GO:0002028

regulation of sodium ion transport

0.32

GO:0003723

RNA binding

0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IVW1|ARL17_HUMAN
ADP-ribosylation factor-like protein 17
Search

0.95	ADP-ribosylation factor-like protein 17

0.36	GO:0016192	vesicle-mediated transport
0.35	GO:0008104	protein localization
0.35	GO:0042886	amide transport
0.34	GO:0071702	organic substance transport
0.34	GO:0040007	growth
0.34	GO:0007163	establishment or maintenance of cell polarity
0.34	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.34	GO:0051641	cellular localization
0.34	GO:1903047	mitotic cell cycle process
0.33	GO:0016055	Wnt signaling pathway

0.66	GO:0005525	GTP binding
0.33	GO:0005102	receptor binding
0.33	GO:0003729	mRNA binding
0.33	GO:0016868	intramolecular transferase activity, phosphotransferases
0.33	GO:0016301	kinase activity
0.33	GO:0030234	enzyme regulator activity
0.33	GO:0003924	GTPase activity
0.32	GO:0004412	homoserine dehydrogenase activity
0.32	GO:0000287	magnesium ion binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.44	GO:0005622	intracellular
0.37	GO:0012505	endomembrane system
0.35	GO:0043227	membrane-bounded organelle
0.33	GO:0005934	cellular bud tip
0.33	GO:0005935	cellular bud neck
0.33	GO:0005578	proteinaceous extracellular matrix
0.32	GO:0005615	extracellular space
0.32	GO:0031975	envelope
0.32	GO:0044422	organelle part
0.32	GO:0005886	plasma membrane

0.33

EC:5.4.2

GO:0016868

sp|Q8IVW4|CDKL3_HUMAN
Cyclin-dependent kinase-like 3
Search

CDKL3

0.95	Cyclin dependent kinase like 3

0.63	GO:0006468	protein phosphorylation
0.51	GO:0097484	dendrite extension
0.51	GO:0050775	positive regulation of dendrite morphogenesis
0.50	GO:0030517	negative regulation of axon extension
0.49	GO:0051726	regulation of cell cycle
0.36	GO:1903955	positive regulation of protein targeting to mitochondrion
0.34	GO:0006470	protein dephosphorylation
0.34	GO:0007548	sex differentiation
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0060089	molecular transducer activity
0.34	GO:0005515	protein binding
0.34	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0003735	structural constituent of ribosome
0.32	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.46	GO:0005634	nucleus
0.45	GO:0005813	centrosome
0.35	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.3.16

GO:0004721

sp|Q8IVW6|ARI3B_HUMAN
AT-rich interactive domain-containing protein 3B
Search

ARID3B

0.96	AT-rich interactive domain-containing protein 3B

0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development

0.62	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.60	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part

sp|Q8IVW8|SPNS2_HUMAN
Protein spinster homolog 2
Search

SPNS2

0.97	Sphingolipid transporter 2

0.59	GO:0003376	sphingosine-1-phosphate signaling pathway
0.57	GO:0048073	regulation of eye pigmentation
0.55	GO:0048535	lymph node development
0.55	GO:0001782	B cell homeostasis
0.55	GO:0043029	T cell homeostasis
0.55	GO:0072676	lymphocyte migration
0.55	GO:0055085	transmembrane transport
0.54	GO:0002920	regulation of humoral immune response
0.53	GO:0060348	bone development
0.52	GO:0006869	lipid transport

0.60

GO:0046624

sphingolipid transporter activity

0.48	GO:0005765	lysosomal membrane
0.45	GO:0031982	vesicle
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IVY1|CA210_HUMAN
Type III endosome membrane protein TEMP
Search

0.97	Type III endosome membrane protein TEMP

0.60	GO:0055037	recycling endosome
0.59	GO:0005769	early endosome
0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IW00|VSTM4_HUMAN
V-set and transmembrane domain-containing protein 4
Search

VSTM4

0.97	V-set and transmembrane domain-containing protein 4

0.40	GO:0005886	plasma membrane
0.36	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q8IW03|SIAH3_HUMAN
Seven in absentia homolog 3
Search

SIAH3

0.53	E3 ubiquitin-protein ligase

0.78	GO:1903215	negative regulation of protein targeting to mitochondrion
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination
0.70	GO:0007275	multicellular organism development
0.67	GO:0031647	regulation of protein stability

0.54	GO:0046872	metal ion binding
0.34	GO:0016874	ligase activity

0.61	GO:0005634	nucleus
0.53	GO:0005739	mitochondrion

0.34

GO:0016874

sp|Q8IW19|APLF_HUMAN
Aprataxin and PNK-like factor
Search

APLF

0.93	Aprataxin and PNKP like factor

0.87	GO:0051106	positive regulation of DNA ligation
0.86	GO:0000012	single strand break repair
0.76	GO:0006302	double-strand break repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.62	GO:0045191	regulation of isotype switching

0.77	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.72	GO:0008408	3'-5' exonuclease activity
0.72	GO:0004520	endodeoxyribonuclease activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.39	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding

0.82	GO:0035861	site of double-strand break
0.69	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol

0.77

EC:4.2.99.18

GO:0003906

sp|Q8IW35|CEP97_HUMAN
Centrosomal protein of 97 kDa
Search

CEP97

0.83	Centrosomal protein of

0.86	GO:1902018	negative regulation of cilium assembly
0.85	GO:1901673	regulation of mitotic spindle assembly
0.43	GO:0097711	ciliary basal body-plasma membrane docking

0.40

GO:0005516

calmodulin binding

0.77	GO:0005813	centrosome
0.68	GO:0005829	cytosol
0.59	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q8IW36|ZN695_HUMAN
Zinc finger protein 695
Search

0.76	Zinc finger protein 695

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0003700	DNA binding transcription factor activity
0.30	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043230	extracellular organelle
0.38	GO:0005615	extracellular space
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043228	non-membrane-bounded organelle
0.35	GO:0044422	organelle part

sp|Q8IW40|CC103_HUMAN
Coiled-coil domain-containing protein 103
Search

CCDC103

0.97	Coiled-coil domain-containing protein 103

0.83	GO:0070286	axonemal dynein complex assembly
0.82	GO:0001947	heart looping
0.81	GO:0003341	cilium movement
0.75	GO:0071907	determination of digestive tract left/right asymmetry
0.66	GO:0003146	heart jogging

0.63

GO:0042803

protein homodimerization activity

0.72	GO:0005929	cilium
0.69	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.60	GO:0044430	cytoskeletal part
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IW41|MAPK5_HUMAN
MAP kinase-activated protein kinase 5
Search

MAPKAPK5

0.97	Mitogen-activated protein kinase-activated protein kinase 5

0.63	GO:0006468	protein phosphorylation
0.55	GO:0090400	stress-induced premature senescence
0.54	GO:0007265	Ras protein signal transduction
0.54	GO:1904355	positive regulation of telomere capping
0.53	GO:0051973	positive regulation of telomerase activity
0.53	GO:0032212	positive regulation of telomere maintenance via telomerase
0.48	GO:0032007	negative regulation of TOR signaling
0.47	GO:0006417	regulation of translation
0.46	GO:0018209	peptidyl-serine modification
0.43	GO:0007166	cell surface receptor signaling pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0002039	p53 binding
0.50	GO:0051019	mitogen-activated protein kinase binding
0.46	GO:0005516	calmodulin binding
0.41	GO:0004871	signal transducer activity
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.40	GO:0032156	septin cytoskeleton
0.36	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.34

EC:1.2.1

GO:0016620

sp|Q8IW45|NNRD_HUMAN
ATP-dependent (S)-NAD(P)H-hydrate dehydratase
Search

CARKD

0.75	ATP-dependent (S)-NAD(P)H-hydrate dehydratase

0.62	GO:0019362	pyridine nucleotide metabolic process
0.39	GO:0016310	phosphorylation
0.34	GO:0072525	pyridine-containing compound biosynthetic process
0.34	GO:0009108	coenzyme biosynthetic process
0.33	GO:0009165	nucleotide biosynthetic process

0.80	GO:0047453	ATP-dependent NAD(P)H-hydrate dehydratase activity
0.78	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016301	kinase activity
0.33	GO:0005515	protein binding

0.50	GO:0005739	mitochondrion
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:4.2.1.93	GO:0047453
0.80	KEGG:R00129	GO:0047453

sp|Q8IW50|F219A_HUMAN
Protein FAM219A
Search

sp|Q8IW52|SLIK4_HUMAN
SLIT and NTRK-like protein 4
Search

SLITRK4

0.97	SLIT and NTRK like family member 4

0.53	GO:0007409	axonogenesis
0.53	GO:0051965	positive regulation of synapse assembly
0.35	GO:0007625	grooming behavior
0.35	GO:0021756	striatum development
0.35	GO:0048813	dendrite morphogenesis
0.34	GO:0043588	skin development
0.34	GO:0030534	adult behavior
0.34	GO:0072358	cardiovascular system development
0.34	GO:0007268	chemical synaptic transmission
0.34	GO:0009410	response to xenobiotic stimulus

0.33

GO:0005515

protein binding

0.37	GO:0043235	receptor complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IW70|T151B_HUMAN
Transmembrane protein 151B
Search

TMEM151B

0.91	LOW QUALITY PROTEIN: transmembrane protein 151B

0.30

GO:0044425

membrane part

sp|Q8IW75|SPA12_HUMAN
Serpin A12
Search

SERPINA12

0.72	Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

0.63	GO:0046628	positive regulation of insulin receptor signaling pathway
0.62	GO:0090181	regulation of cholesterol metabolic process
0.61	GO:0090207	regulation of triglyceride metabolic process
0.60	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.60	GO:0045721	negative regulation of gluconeogenesis
0.59	GO:0051055	negative regulation of lipid biosynthetic process
0.57	GO:0010951	negative regulation of endopeptidase activity
0.54	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.38	GO:0002438	acute inflammatory response to antigenic stimulus
0.37	GO:0007595	lactation

0.59	GO:0004867	serine-type endopeptidase inhibitor activity
0.50	GO:0008201	heparin binding
0.46	GO:0002020	protease binding
0.43	GO:0042802	identical protein binding
0.36	GO:0005496	steroid binding
0.35	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0008233	peptidase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0016874	ligase activity

0.73	GO:0005615	extracellular space
0.44	GO:0005886	plasma membrane
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0005794	Golgi apparatus
0.34	GO:1903561	extracellular vesicle
0.32	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.34

GO:0008233

sp|Q8IW92|GLBL2_HUMAN
Beta-galactosidase-1-like protein 2
Search

GLB1L2

0.41	Beta-galactosidase

0.60	GO:0005975	carbohydrate metabolic process
0.36	GO:0060271	cilium assembly

0.77

GO:0004565

beta-galactosidase activity

0.47	GO:0005773	vacuole
0.37	GO:0097546	ciliary base
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:3.2.1.23

GO:0004565

sp|Q8IW93|ARHGJ_HUMAN
Rho guanine nucleotide exchange factor 19
Search

ARHGEF19

0.95	Rho guanine nucleotide exchange factor 5

0.75	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.56	GO:0032956	regulation of actin cytoskeleton organization
0.55	GO:0042060	wound healing
0.47	GO:0002408	myeloid dendritic cell chemotaxis
0.47	GO:0035556	intracellular signal transduction
0.47	GO:0071803	positive regulation of podosome assembly
0.45	GO:1904591	positive regulation of protein import
0.45	GO:0046330	positive regulation of JNK cascade
0.44	GO:1902905	positive regulation of supramolecular fiber organization

0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0005096	GTPase activator activity
0.34	GO:0008289	lipid binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005829	cytosol
0.42	GO:0005654	nucleoplasm
0.38	GO:0005886	plasma membrane
0.36	GO:0002102	podosome
0.35	GO:0030054	cell junction
0.34	GO:0042995	cell projection

sp|Q8IWA0|WDR75_HUMAN
WD repeat-containing protein 75
Search

WDR75

0.92	WD repeat-containing protein 75

0.85	GO:2000234	positive regulation of rRNA processing
0.82	GO:1903146	regulation of autophagy of mitochondrion
0.81	GO:0045943	positive regulation of transcription by RNA polymerase I
0.81	GO:1903955	positive regulation of protein targeting to mitochondrion
0.41	GO:0006364	rRNA processing
0.38	GO:0006351	transcription, DNA-templated

0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0003723	RNA binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.70	GO:0005730	nucleolus
0.37	GO:0005654	nucleoplasm

sp|Q8IWA4|MFN1_HUMAN
Mitofusin-1
Search

MFN1

0.91	Mitochondrial transmembrane GTPase FZO-2

0.85	GO:0008053	mitochondrial fusion
0.51	GO:0048662	negative regulation of smooth muscle cell proliferation
0.49	GO:0051646	mitochondrion localization
0.42	GO:0007006	mitochondrial membrane organization
0.41	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.41	GO:0061734	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
0.41	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.40	GO:0034497	protein localization to phagophore assembly site
0.40	GO:0046580	negative regulation of Ras protein signal transduction
0.40	GO:0001825	blastocyst formation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0003676	nucleic acid binding

0.78	GO:0005741	mitochondrial outer membrane
0.46	GO:0098573	intrinsic component of mitochondrial membrane
0.37	GO:0015630	microtubule cytoskeleton
0.37	GO:0031301	integral component of organelle membrane
0.36	GO:0098798	mitochondrial protein complex
0.36	GO:1904115	axon cytoplasm
0.35	GO:0098796	membrane protein complex
0.34	GO:0005829	cytosol
0.33	GO:0005743	mitochondrial inner membrane

sp|Q8IWA5|CTL2_HUMAN
Choline transporter-like protein 2
Search

SLC44A2

0.93	LOW QUALITY PROTEIN: choline transporter-like protein 2

0.37	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0006656	phosphatidylcholine biosynthetic process
0.35	GO:0015871	choline transport
0.34	GO:0007165	signal transduction
0.33	GO:0055085	transmembrane transport

0.35	GO:0015220	choline transmembrane transporter activity
0.34	GO:0004871	signal transducer activity
0.34	GO:0003725	double-stranded RNA binding
0.33	GO:0005515	protein binding

0.36	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0035579	specific granule membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IWA6|CCD60_HUMAN
Coiled-coil domain-containing protein 60
Search

CCDC60

0.96	Coiled-coil domain-containing protein 60

0.52

GO:0009607

response to biotic stimulus

0.51

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q8IWB1|IPRI_HUMAN
Inositol 1,4,5-trisphosphate receptor-interacting protein
Search

ITPRIP

0.97	Inositol 1,4,5-trisphosphate receptor-interacting protein (Fragment)

0.63	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.59	GO:0006469	negative regulation of protein kinase activity

0.60	GO:0004860	protein kinase inhibitor activity
0.50	GO:0005515	protein binding

0.49	GO:0005886	plasma membrane
0.45	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q8IWB4|S31A7_HUMAN
Spermatogenesis-associated protein 31A7
Search

0.97	Spermatogenesis-associated protein 31A7

0.60	GO:0007283	spermatogenesis
0.55	GO:0030154	cell differentiation

0.30

GO:0044425

membrane part

sp|Q8IWB6|TEX14_HUMAN
Inactive serine/threonine-protein kinase TEX14
Search

TEX14

0.88	Testis expressed 14, intercellular bridge forming factor

0.69	GO:0043063	intercellular bridge organization
0.68	GO:0051306	mitotic sister chromatid separation
0.65	GO:0007140	male meiotic nuclear division
0.64	GO:0032091	negative regulation of protein binding
0.64	GO:0032466	negative regulation of cytokinesis
0.64	GO:1990823	response to leukemia inhibitory factor
0.64	GO:0008608	attachment of spindle microtubules to kinetochore
0.63	GO:0006468	protein phosphorylation
0.63	GO:0007094	mitotic spindle assembly checkpoint
0.60	GO:0071345	cellular response to cytokine stimulus

0.64	GO:0004672	protein kinase activity
0.60	GO:0019901	protein kinase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0045171	intercellular bridge
0.64	GO:0030496	midbody
0.61	GO:0000776	kinetochore
0.42	GO:0000779	condensed chromosome, centromeric region
0.39	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm

sp|Q8IWB7|WDFY1_HUMAN
WD repeat and FYVE domain-containing protein 1
Search

WDFY1

0.96	WD repeat and FYVE domain-containing protein 1

0.58	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway
0.58	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
0.34	GO:0006886	intracellular protein transport
0.34	GO:0016192	vesicle-mediated transport

0.54	GO:0005545	1-phosphatidylinositol binding
0.53	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.53	GO:0005769	early endosome
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.35	GO:0030117	membrane coat

sp|Q8IWB9|TEX2_HUMAN
Testis-expressed protein 2
Search

TEX2

0.95	Testis expressed gene 2

0.36	GO:0006397	mRNA processing
0.36	GO:0090501	RNA phosphodiester bond hydrolysis
0.35	GO:0006468	protein phosphorylation
0.33	GO:0006869	lipid transport
0.30	GO:0007165	signal transduction
0.30	GO:0006629	lipid metabolic process

0.43	GO:0008289	lipid binding
0.36	GO:0004540	ribonuclease activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|Q8IWC1|MA7D3_HUMAN
MAP7 domain-containing protein 3
Search

MAP7D3

0.88	MAP7 domain-containing protein 3

0.76	GO:0000226	microtubule cytoskeleton organization
0.53	GO:0051258	protein polymerization
0.51	GO:0097435	supramolecular fiber organization
0.34	GO:0006413	translational initiation
0.33	GO:0072659	protein localization to plasma membrane
0.33	GO:0007163	establishment or maintenance of cell polarity
0.33	GO:0006970	response to osmotic stress
0.33	GO:0016192	vesicle-mediated transport

0.51	GO:0008017	microtubule binding
0.40	GO:0005198	structural molecule activity
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0005102	receptor binding

0.71	GO:0015630	microtubule cytoskeleton
0.39	GO:0044430	cytoskeletal part
0.38	GO:0005829	cytosol
0.33	GO:0016323	basolateral plasma membrane
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0099512	supramolecular fiber
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q8IWD4|CC117_HUMAN
Coiled-coil domain-containing protein 117
Search

CCDC117

0.95	Coiled-coil domain-containing protein 117

0.51	GO:0051259	protein oligomerization
0.51	GO:0032781	positive regulation of ATPase activity
0.49	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.45	GO:0043043	peptide biosynthetic process
0.43	GO:0044267	cellular protein metabolic process
0.41	GO:0009059	macromolecule biosynthetic process

0.53	GO:0005515	protein binding
0.51	GO:0001671	ATPase activator activity
0.47	GO:0003735	structural constituent of ribosome

0.45

GO:0005840

ribosome

sp|Q8IWD5|MFS6L_HUMAN
Major facilitator superfamily domain-containing protein 6-like
Search

MFSD6L

0.83	Major facilitator superfamily domain-containing protein 6

0.30

GO:0044425

membrane part

sp|Q8IWE2|NXP20_HUMAN
Protein NOXP20
Search

sp|Q8IWE4|DCNL3_HUMAN
DCN1-like protein 3
Search

sp|Q8IWE5|PKHM2_HUMAN
Pleckstrin homology domain-containing family M member 2
Search

PLEKHM2

0.95	Pleckstrin like proteiny domain-containing family M member 2

0.87	GO:1903527	positive regulation of membrane tubulation
0.84	GO:0032418	lysosome localization
0.80	GO:0007030	Golgi organization
0.73	GO:0032880	regulation of protein localization
0.38	GO:0006508	proteolysis

0.84	GO:0019894	kinesin binding
0.40	GO:0070001	aspartic-type peptidase activity
0.39	GO:0004175	endopeptidase activity

0.76	GO:0010008	endosome membrane
0.30	GO:0044425	membrane part

sp|Q8IWF2|FXRD2_HUMAN
FAD-dependent oxidoreductase domain-containing protein 2
Search

FOXRED2

0.97	FAD-dependent oxidoreductase domain-containing protein 2

0.76	GO:0030433	ubiquitin-dependent ERAD pathway
0.43	GO:0006662	glycerol ether metabolic process
0.42	GO:0045454	cell redox homeostasis
0.42	GO:0002191	cap-dependent translational initiation
0.40	GO:0001731	formation of translation preinitiation complex
0.40	GO:0006446	regulation of translational initiation
0.39	GO:0055114	oxidation-reduction process

0.62	GO:0050660	flavin adenine dinucleotide binding
0.42	GO:0015035	protein disulfide oxidoreductase activity
0.42	GO:0098808	mRNA cap binding
0.39	GO:0003743	translation initiation factor activity
0.36	GO:0005515	protein binding
0.34	GO:0004497	monooxygenase activity

0.78	GO:0005788	endoplasmic reticulum lumen
0.40	GO:0016282	eukaryotic 43S preinitiation complex
0.40	GO:0033290	eukaryotic 48S preinitiation complex
0.40	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IWF6|DEN6A_HUMAN
Protein DENND6A
Search

DENND6A

0.97	DENN domain containing 6A

0.71	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin
0.66	GO:0065009	regulation of molecular function

0.85

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.67	GO:0055037	recycling endosome
0.47	GO:0043231	intracellular membrane-bounded organelle

sp|Q8IWF7|U2D2L_HUMAN
Putative ubiquitin-conjugating enzyme E2 D2-like protein
Search

0.51	Ubiquitin conjugating enzyme E2 (Fragment)

0.43	GO:0032446	protein modification by small protein conjugation
0.43	GO:1902916	positive regulation of protein polyubiquitination
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0036503	ERAD pathway
0.39	GO:0030466	chromatin silencing at silent mating-type cassette
0.36	GO:0000022	mitotic spindle elongation
0.35	GO:0008283	cell proliferation
0.35	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.35	GO:0031505	fungal-type cell wall organization
0.34	GO:0018205	peptidyl-lysine modification

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.43	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0016874	ligase activity
0.36	GO:0005515	protein binding
0.35	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0019789	SUMO transferase activity
0.34	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.41	GO:0000151	ubiquitin ligase complex
0.37	GO:0043234	protein complex
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005720	nuclear heterochromatin
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0000794	condensed nuclear chromosome
0.35	GO:0031984	organelle subcompartment
0.34	GO:0015629	actin cytoskeleton
0.34	GO:0044430	cytoskeletal part
0.33	GO:0005829	cytosol

0.38	EC:6	GO:0016874
0.43	KEGG:R03876	GO:0004842

sp|Q8IWF9|CCD83_HUMAN
Coiled-coil domain-containing protein 83
Search

CCDC83

0.93	Coiled-coil domain-containing protein 83

sp|Q8IWG1|WDR63_HUMAN
WD repeat-containing protein 63
Search

WDR63

0.97	WD repeat-containing protein 63

0.74

GO:0007018

microtubule-based movement

0.86	GO:0045504	dynein heavy chain binding
0.86	GO:0045503	dynein light chain binding
0.85	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed

0.79

GO:0030286

dynein complex

0.85

EC:3.6.4.4

GO:0008574

sp|Q8IWI9|MGAP_HUMAN
MAX gene-associated protein
Search

MGA

0.92	MAX gene associated

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.43	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process
0.40	GO:0070317	negative regulation of G0 to G1 transition

0.65	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding

0.82	GO:0071339	MLL1 complex
0.41	GO:0005667	transcription factor complex

sp|Q8IWJ2|GCC2_HUMAN
GRIP and coiled-coil domain-containing protein 2
Search

GCC2

0.95	GRIP and coiled-coil domain-containing protein 2

0.87	GO:0071955	recycling endosome to Golgi transport
0.86	GO:0034499	late endosome to Golgi transport
0.86	GO:0090161	Golgi ribbon formation
0.85	GO:0006622	protein targeting to lysosome
0.85	GO:0070861	regulation of protein exit from endoplasmic reticulum
0.83	GO:0034067	protein localization to Golgi apparatus
0.83	GO:0034453	microtubule anchoring
0.81	GO:0031023	microtubule organizing center organization
0.45	GO:0043001	Golgi to plasma membrane protein transport
0.34	GO:0046604	positive regulation of mitotic centrosome separation

0.73	GO:0042802	identical protein binding
0.34	GO:0008536	Ran GTPase binding
0.33	GO:0005096	GTPase activator activity

0.78	GO:0005802	trans-Golgi network
0.69	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.33	GO:0005643	nuclear pore
0.33	GO:0005813	centrosome
0.30	GO:0016020	membrane

sp|Q8IWK6|AGRA3_HUMAN
Adhesion G protein-coupled receptor A3
Search

ADGRA3

0.95	Adhesion G protein-coupled receptor A3

0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0097475	motor neuron migration
0.37	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway
0.37	GO:0060027	convergent extension involved in gastrulation
0.37	GO:0003401	axis elongation
0.36	GO:0198738	cell-cell signaling by wnt

0.71	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005515	protein binding

0.67	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IWL1|SFPA2_HUMAN
Pulmonary surfactant-associated protein A2
Search

SFTPA1

0.95	Pulmonary surfactant-associated protein A

0.60	GO:0007585	respiratory gaseous exchange
0.53	GO:0008228	opsonization
0.46	GO:0002253	activation of immune response
0.43	GO:0033189	response to vitamin A
0.43	GO:0071732	cellular response to nitric oxide
0.42	GO:0045089	positive regulation of innate immune response
0.42	GO:0002764	immune response-regulating signaling pathway
0.42	GO:0055093	response to hyperoxia
0.42	GO:0070741	response to interleukin-6
0.42	GO:0070849	response to epidermal growth factor

0.53	GO:0030246	carbohydrate binding
0.47	GO:0005201	extracellular matrix structural constituent
0.41	GO:0046872	metal ion binding
0.39	GO:0042302	structural constituent of cuticle
0.38	GO:0005319	lipid transporter activity
0.36	GO:0005515	protein binding
0.35	GO:0036094	small molecule binding
0.34	GO:0001540	amyloid-beta binding
0.34	GO:0008201	heparin binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity

0.74	GO:0005581	collagen trimer
0.55	GO:0005578	proteinaceous extracellular matrix
0.54	GO:0005615	extracellular space
0.45	GO:0042599	lamellar body
0.43	GO:0045334	clathrin-coated endocytic vesicle
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0005771	multivesicular body
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0044420	extracellular matrix component
0.39	GO:0031984	organelle subcompartment

sp|Q8IWL2|SFTA1_HUMAN
Pulmonary surfactant-associated protein A1
Search

SFTPA1

0.95	Pulmonary surfactant-associated protein A

0.56	GO:0007585	respiratory gaseous exchange
0.50	GO:0008228	opsonization
0.44	GO:0002253	activation of immune response
0.43	GO:0035987	endodermal cell differentiation
0.41	GO:0033189	response to vitamin A
0.41	GO:0072376	protein activation cascade
0.41	GO:0071732	cellular response to nitric oxide
0.41	GO:0045089	positive regulation of innate immune response
0.41	GO:0055093	response to hyperoxia
0.41	GO:0002764	immune response-regulating signaling pathway

0.52	GO:0005201	extracellular matrix structural constituent
0.50	GO:0030246	carbohydrate binding
0.40	GO:0046872	metal ion binding
0.40	GO:0042302	structural constituent of cuticle
0.39	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0005319	lipid transporter activity
0.37	GO:0005515	protein binding
0.35	GO:0036094	small molecule binding
0.33	GO:0004930	G-protein coupled receptor activity

0.73	GO:0005581	collagen trimer
0.53	GO:0031012	extracellular matrix
0.53	GO:0005615	extracellular space
0.43	GO:0042599	lamellar body
0.41	GO:0045334	clathrin-coated endocytic vesicle
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005771	multivesicular body
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.34	GO:1903561	extracellular vesicle

sp|Q8IWL3|HSC20_HUMAN
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial
Search

HSCB

0.95	HscB mitochondrial iron-sulfur cluster co-chaperone

0.81	GO:0032781	positive regulation of ATPase activity
0.78	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.72	GO:0051259	protein oligomerization
0.61	GO:0031163	metallo-sulfur cluster assembly
0.55	GO:0006790	sulfur compound metabolic process
0.53	GO:0051188	cofactor biosynthetic process
0.37	GO:0006457	protein folding

0.82	GO:0001671	ATPase activator activity
0.77	GO:0051087	chaperone binding
0.61	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding

0.57	GO:0005829	cytosol
0.52	GO:0005634	nucleus
0.52	GO:0005739	mitochondrion

sp|Q8IWL8|STH_HUMAN
Saitohin
Search

0.64

GO:0048026

positive regulation of mRNA splicing, via spliceosome

0.49

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.59	GO:0048471	perinuclear region of cytoplasm

sp|Q8IWN6|F223A_HUMAN
Protein FAM223A
Search

sp|Q8IWN7|RP1L1_HUMAN
Retinitis pigmentosa 1-like 1 protein
Search

RP1L1

0.60	Retinitis pigmentosa 1-like 1 protein (Fragment)

0.62	GO:0035556	intracellular signal transduction
0.55	GO:0042461	photoreceptor cell development
0.54	GO:0035082	axoneme assembly
0.54	GO:0060041	retina development in camera-type eye
0.47	GO:0045494	photoreceptor cell maintenance
0.45	GO:0007601	visual perception
0.34	GO:0060026	convergent extension
0.34	GO:0021549	cerebellum development
0.32	GO:0060255	regulation of macromolecule metabolic process
0.32	GO:0051641	cellular localization

0.32	GO:0003676	nucleic acid binding
0.32	GO:0008995	ribonuclease E activity
0.32	GO:0000030	mannosyltransferase activity
0.32	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding
0.32	GO:0004521	endoribonuclease activity
0.32	GO:0000287	magnesium ion binding
0.31	GO:0008270	zinc ion binding

0.53	GO:0005930	axoneme
0.47	GO:0032391	photoreceptor connecting cilium
0.47	GO:0001750	photoreceptor outer segment
0.46	GO:0070062	extracellular exosome
0.43	GO:0005874	microtubule
0.32	GO:0099115	chromosome, subtelomeric region
0.32	GO:0044459	plasma membrane part
0.32	GO:0098562	cytoplasmic side of membrane
0.32	GO:0000781	chromosome, telomeric region
0.32	GO:0005730	nucleolus

0.32

GO:0000030

sp|Q8IWP9|CC28A_HUMAN
Coiled-coil domain-containing protein 28A
Search

CCDC28A

0.96	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 28A

0.58	GO:0060271	cilium assembly
0.54	GO:0035023	regulation of Rho protein signal transduction
0.48	GO:0065009	regulation of molecular function

0.54

GO:0005089

Rho guanyl-nucleotide exchange factor activity

0.47

GO:0005813

centrosome

sp|Q8IWQ3|BRSK2_HUMAN
Serine/threonine-protein kinase BRSK2
Search

BRSK2

0.85	BR serine/threonine-protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.58	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.58	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.57	GO:0000086	G2/M transition of mitotic cell cycle
0.55	GO:0036503	ERAD pathway
0.53	GO:0030010	establishment of cell polarity
0.53	GO:0018209	peptidyl-serine modification
0.53	GO:0007409	axonogenesis
0.53	GO:0031532	actin cytoskeleton reorganization

0.63	GO:0004672	protein kinase activity
0.57	GO:0051117	ATPase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.47	GO:0000287	magnesium ion binding

0.57	GO:0005813	centrosome
0.49	GO:0005783	endoplasmic reticulum
0.42	GO:0005634	nucleus

sp|Q8IWR0|Z3H7A_HUMAN
Zinc finger CCCH domain-containing protein 7A
Search

ZC3H7A

0.97	Zinc finger CCCH type-containing 7 A

0.63

GO:0035196

production of miRNAs involved in gene silencing by miRNA

0.64	GO:0035198	miRNA binding
0.53	GO:0046872	metal ion binding

0.34

GO:0005634

nucleus

sp|Q8IWR1|TRI59_HUMAN
Tripartite motif-containing protein 59
Search

TRIM59

0.86	Tripartite motif-containing protein 59

0.57	GO:0046597	negative regulation of viral entry into host cell
0.56	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.54	GO:0045087	innate immune response
0.52	GO:1902532	negative regulation of intracellular signal transduction
0.51	GO:0016567	protein ubiquitination
0.50	GO:0060271	cilium assembly
0.41	GO:1902187	negative regulation of viral release from host cell
0.41	GO:0032897	negative regulation of viral transcription
0.41	GO:0010332	response to gamma radiation
0.40	GO:0016239	positive regulation of macroautophagy

0.62	GO:0008270	zinc ion binding
0.52	GO:0004842	ubiquitin-protein transferase activity
0.51	GO:0061659	ubiquitin-like protein ligase activity
0.37	GO:0016874	ligase activity
0.35	GO:0005515	protein binding
0.32	GO:0043142	single-stranded DNA-dependent ATPase activity

0.52	GO:0030992	intraciliary transport particle B
0.51	GO:0005929	cilium
0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005813	centrosome
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.39	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0097505	Rad6-Rad18 complex
0.31	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.37	EC:6	GO:0016874
0.52	KEGG:R03876	GO:0004842

sp|Q8IWS0|PHF6_HUMAN
PHD finger protein 6
Search

0.56	PHD finger protein 6

0.38	GO:0007346	regulation of mitotic cell cycle
0.36	GO:0006468	protein phosphorylation
0.35	GO:0060255	regulation of macromolecule metabolic process
0.30	GO:0090304	nucleic acid metabolic process
0.30	GO:0009890	negative regulation of biosynthetic process
0.30	GO:0018130	heterocycle biosynthetic process
0.30	GO:1901362	organic cyclic compound biosynthetic process
0.30	GO:0048523	negative regulation of cellular process
0.30	GO:0019438	aromatic compound biosynthetic process
0.30	GO:0080090	regulation of primary metabolic process

0.53	GO:0046872	metal ion binding
0.40	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0043021	ribonucleoprotein complex binding
0.30	GO:0097110	scaffold protein binding
0.30	GO:0051219	phosphoprotein binding
0.30	GO:0003723	RNA binding
0.30	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.36	GO:0005634	nucleus
0.30	GO:0043234	protein complex
0.30	GO:0044422	organelle part
0.30	GO:0016020	membrane
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0043232	intracellular non-membrane-bounded organelle

0.40

EC:2.7.11.22

GO:0004693

sp|Q8IWT0|ARCH_HUMAN
Protein archease
Search

ZBTB8OS

0.97	Zinc finger and BTB domain containing 8 opposite strand

0.78	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.44	GO:0048680	positive regulation of axon regeneration
0.39	GO:0006955	immune response

0.42	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding
0.35	GO:0003723	RNA binding

0.84	GO:0072669	tRNA-splicing ligase complex
0.47	GO:0070062	extracellular exosome
0.42	GO:0005579	membrane attack complex
0.40	GO:0005654	nucleoplasm

sp|Q8IWT1|SCN4B_HUMAN
Sodium channel subunit beta-4
Search

SCN4B

0.97	Sodium voltage-gated channel beta subunit 4

0.65	GO:0086016	AV node cell action potential
0.64	GO:0086012	membrane depolarization during cardiac muscle cell action potential
0.64	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.63	GO:0010765	positive regulation of sodium ion transport
0.63	GO:0086002	cardiac muscle cell action potential involved in contraction
0.63	GO:0086091	regulation of heart rate by cardiac conduction
0.62	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.57	GO:0035725	sodium ion transmembrane transport

0.66	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential
0.62	GO:0017080	sodium channel regulator activity
0.61	GO:0044325	ion channel binding
0.40	GO:0022832	voltage-gated channel activity
0.39	GO:0022839	ion gated channel activity
0.39	GO:0008381	mechanosensitive ion channel activity

0.63	GO:0014704	intercalated disc
0.60	GO:0001518	voltage-gated sodium channel complex

sp|Q8IWT3|CUL9_HUMAN
Cullin-9
Search

CUL9

0.97

Cullin-9

0.71	GO:0006511	ubiquitin-dependent protein catabolic process
0.71	GO:0007088	regulation of mitotic nuclear division
0.70	GO:0000226	microtubule cytoskeleton organization
0.68	GO:0016567	protein ubiquitination
0.44	GO:0050775	positive regulation of dendrite morphogenesis
0.43	GO:0001837	epithelial to mesenchymal transition
0.43	GO:0001890	placenta development
0.43	GO:0001570	vasculogenesis
0.42	GO:0000281	mitotic cytokinesis
0.37	GO:0043687	post-translational protein modification

0.77	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0046872	metal ion binding
0.35	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0000987	proximal promoter sequence-specific DNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046983	protein dimerization activity

0.72	GO:0031461	cullin-RING ubiquitin ligase complex
0.52	GO:1990393	3M complex
0.49	GO:0005829	cytosol
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005813	centrosome
0.40	GO:0005794	Golgi apparatus
0.33	GO:0005634	nucleus

sp|Q8IWT6|LRC8A_HUMAN
Volume-regulated anion channel subunit LRRC8A
Search

LRRC8A

0.93	Leucine-rich repeat-containing protein 8A

0.42	GO:0006884	cell volume homeostasis
0.41	GO:0006970	response to osmotic stress
0.39	GO:0098656	anion transmembrane transport

0.44	GO:0005225	volume-sensitive anion channel activity
0.40	GO:0042802	identical protein binding

0.40	GO:0009986	cell surface
0.40	GO:0034702	ion channel complex
0.36	GO:0005886	plasma membrane

sp|Q8IWU2|LMTK2_HUMAN
Serine/threonine-protein kinase LMTK2
Search

LMTK2

0.95	Serine/threonine-protein kinase LMTK2

0.63	GO:0006468	protein phosphorylation
0.45	GO:0033572	transferrin transport
0.45	GO:0001881	receptor recycling
0.45	GO:0045022	early endosome to late endosome transport
0.44	GO:0032456	endocytic recycling
0.44	GO:0018210	peptidyl-threonine modification
0.44	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.43	GO:0018209	peptidyl-serine modification
0.36	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0048011	neurotrophin TRK receptor signaling pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0070853	myosin VI binding
0.44	GO:0004864	protein phosphatase inhibitor activity

0.44	GO:0055037	recycling endosome
0.43	GO:0005769	early endosome
0.43	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005794	Golgi apparatus
0.41	GO:0030426	growth cone
0.40	GO:0005829	cytosol
0.40	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|Q8IWU4|ZNT8_HUMAN
Zinc transporter 8
Search

SLC30A8

0.85	Solute carrier family 30 (zinc transporter), member 8

0.81	GO:0055069	zinc ion homeostasis
0.76	GO:0071577	zinc II ion transmembrane transport
0.73	GO:0072503	cellular divalent inorganic cation homeostasis
0.71	GO:0030073	insulin secretion
0.71	GO:0051238	sequestering of metal ion
0.69	GO:0046916	cellular transition metal ion homeostasis
0.68	GO:0009749	response to glucose
0.66	GO:0061088	regulation of sequestering of zinc ion
0.57	GO:0010043	response to zinc ion
0.49	GO:0032846	positive regulation of homeostatic process

0.76	GO:0005385	zinc ion transmembrane transporter activity
0.58	GO:0042803	protein homodimerization activity

0.65	GO:0031410	cytoplasmic vesicle
0.61	GO:0012505	endomembrane system
0.49	GO:0005886	plasma membrane
0.39	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q8IWU5|SULF2_HUMAN
Extracellular sulfatase Sulf-2
Search

SULF2

0.94	Extracellular sulfatase Sulf-2

0.59	GO:0014846	esophagus smooth muscle contraction
0.59	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway
0.58	GO:2000345	regulation of hepatocyte proliferation
0.58	GO:0035413	positive regulation of catenin import into nucleus
0.58	GO:0097421	liver regeneration
0.58	GO:0032836	glomerular basement membrane development
0.58	GO:0003094	glomerular filtration
0.57	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.57	GO:0010575	positive regulation of vascular endothelial growth factor production
0.57	GO:0060384	innervation

0.74	GO:0008484	sulfuric ester hydrolase activity
0.66	GO:0005509	calcium ion binding
0.33	GO:0046983	protein dimerization activity

0.72	GO:0009986	cell surface
0.67	GO:0005794	Golgi apparatus
0.67	GO:0005783	endoplasmic reticulum
0.42	GO:0005886	plasma membrane
0.35	GO:0005615	extracellular space
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:3.1.6

GO:0008484

sp|Q8IWU6|SULF1_HUMAN
Extracellular sulfatase Sulf-1
Search

SULF1

0.94	Extracellular 6-O-endosulfatase

0.60	GO:0014846	esophagus smooth muscle contraction
0.60	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway
0.60	GO:0060686	negative regulation of prostatic bud formation
0.58	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.58	GO:0030336	negative regulation of cell migration
0.58	GO:0060384	innervation
0.58	GO:0002063	chondrocyte development
0.57	GO:0030201	heparan sulfate proteoglycan metabolic process
0.57	GO:0043009	chordate embryonic development
0.56	GO:0001937	negative regulation of endothelial cell proliferation

0.74	GO:0008484	sulfuric ester hydrolase activity
0.63	GO:0005509	calcium ion binding

0.68	GO:0009986	cell surface
0.64	GO:0005794	Golgi apparatus
0.63	GO:0005783	endoplasmic reticulum
0.53	GO:0045121	membrane raft
0.50	GO:0005615	extracellular space
0.41	GO:0005886	plasma membrane
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:3.1.6

GO:0008484

sp|Q8IWU9|TPH2_HUMAN
Tryptophan 5-hydroxylase 2
Search

TPH2

0.97	Neuronal tryptophan hydroxylase

0.84	GO:0042427	serotonin biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.52	GO:0055114	oxidation-reduction process
0.39	GO:0071285	cellular response to lithium ion
0.39	GO:0014823	response to activity
0.38	GO:0046849	bone remodeling
0.38	GO:0045600	positive regulation of fat cell differentiation
0.38	GO:0043627	response to estrogen
0.38	GO:0051384	response to glucocorticoid
0.38	GO:0051592	response to calcium ion

0.84	GO:0004510	tryptophan 5-monooxygenase activity
0.62	GO:0005506	iron ion binding

0.51	GO:0043005	neuron projection
0.34	GO:0005829	cytosol

0.84

EC:1.14.16.4

GO:0004510

sp|Q8IWV1|LAX1_HUMAN
Lymphocyte transmembrane adapter 1
Search

LAX1

0.97	Lymphocyte transmembrane adapter 1

0.76	GO:0051249	regulation of lymphocyte activation
0.74	GO:0006955	immune response
0.65	GO:1903038	negative regulation of leukocyte cell-cell adhesion
0.65	GO:0000188	inactivation of MAPK activity
0.64	GO:0042113	B cell activation
0.64	GO:0002695	negative regulation of leukocyte activation
0.51	GO:0035556	intracellular signal transduction
0.38	GO:0048305	immunoglobulin secretion
0.37	GO:0050851	antigen receptor-mediated signaling pathway
0.37	GO:0070588	calcium ion transmembrane transport

0.67	GO:0042169	SH2 domain binding
0.61	GO:0019901	protein kinase binding
0.37	GO:0005388	calcium-transporting ATPase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005794	Golgi apparatus
0.54	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane
0.39	GO:0045121	membrane raft
0.30	GO:0016021	integral component of membrane

0.37

EC:3.6.3.8

GO:0005388

sp|Q8IWV2|CNTN4_HUMAN
Contactin-4
Search

CNTN4

0.92	LOW QUALITY PROTEIN: contactin-4

0.77	GO:0007411	axon guidance
0.71	GO:0007155	cell adhesion
0.54	GO:0045665	negative regulation of neuron differentiation
0.40	GO:0007420	brain development
0.38	GO:0006501	C-terminal protein lipidation
0.36	GO:0007413	axonal fasciculation
0.35	GO:0048167	regulation of synaptic plasticity
0.34	GO:0045747	positive regulation of Notch signaling pathway

0.47

GO:0005112

Notch binding

0.41	GO:0031225	anchored component of membrane
0.37	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.35	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|Q8IWV7|UBR1_HUMAN
E3 ubiquitin-protein ligase UBR1
Search

UBR1

0.90	Ubiquitin protein ligase E3 component n-recognin 1

0.68	GO:0030163	protein catabolic process
0.61	GO:0071233	cellular response to leucine
0.58	GO:0032007	negative regulation of TOR signaling
0.52	GO:0016567	protein ubiquitination
0.52	GO:0043632	modification-dependent macromolecule catabolic process
0.46	GO:0006508	proteolysis

0.62	GO:0070728	leucine binding
0.60	GO:0008270	zinc ion binding
0.53	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0016874	ligase activity
0.43	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0005515	protein binding

0.54	GO:0000151	ubiquitin ligase complex
0.52	GO:1905369	endopeptidase complex
0.45	GO:0043234	protein complex
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.53	EC:6	GO:0016874
0.53	KEGG:R03876	GO:0004842

sp|Q8IWV8|UBR2_HUMAN
E3 ubiquitin-protein ligase UBR2
Search

UBR2

0.95	Ubiquitin protein ligase E3 component n-recognin 2

0.69	GO:0030163	protein catabolic process
0.60	GO:0033522	histone H2A ubiquitination
0.60	GO:0071233	cellular response to leucine
0.57	GO:0010529	negative regulation of transposition
0.57	GO:0007141	male meiosis I
0.56	GO:0032007	negative regulation of TOR signaling
0.56	GO:0006342	chromatin silencing
0.53	GO:0007131	reciprocal meiotic recombination
0.53	GO:0007283	spermatogenesis
0.52	GO:0043632	modification-dependent macromolecule catabolic process

0.62	GO:0008270	zinc ion binding
0.60	GO:0070728	leucine binding
0.54	GO:0061630	ubiquitin protein ligase activity
0.53	GO:0016874	ligase activity
0.34	GO:0005515	protein binding

0.54	GO:0000151	ubiquitin ligase complex
0.49	GO:0000785	chromatin
0.37	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus

0.53

GO:0016874

sp|Q8IWW6|RHG12_HUMAN
Rho GTPase-activating protein 12
Search

ARHGAP12

0.95	Rho-type GTPase-activating protein 12

0.69	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.58	GO:0006911	phagocytosis, engulfment
0.57	GO:0002011	morphogenesis of an epithelial sheet
0.57	GO:0051058	negative regulation of small GTPase mediated signal transduction
0.52	GO:0007015	actin filament organization

0.70

GO:0005096

GTPase activator activity

0.59	GO:0001891	phagocytic cup
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IWW8|HOT_HUMAN
Hydroxyacid-oxoacid transhydrogenase, mitochondrial
Search

ADHFE1

0.91	Hydroxyacid-oxoacid transhydrogenase

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0006006	glucose metabolic process
0.33	GO:0042254	ribosome biogenesis

0.54	GO:0016491	oxidoreductase activity
0.54	GO:0046872	metal ion binding
0.33	GO:0050661	NADP binding
0.33	GO:0051287	NAD binding

0.37	GO:0005829	cytosol
0.36	GO:0005739	mitochondrion
0.32	GO:0005634	nucleus

0.54

GO:0016491

sp|Q8IWX5|SGPP2_HUMAN
Sphingosine-1-phosphate phosphatase 2
Search

SGPP2

0.97	Sphingosine-1-phosphate phosphatase 2

0.63	GO:0006670	sphingosine metabolic process
0.51	GO:0016311	dephosphorylation
0.38	GO:0006668	sphinganine-1-phosphate metabolic process
0.36	GO:0097191	extrinsic apoptotic signaling pathway
0.36	GO:0097193	intrinsic apoptotic signaling pathway
0.36	GO:0030148	sphingolipid biosynthetic process

0.65	GO:0042392	sphingosine-1-phosphate phosphatase activity
0.38	GO:0070780	dihydrosphingosine-1-phosphate phosphatase activity

0.52	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|Q8IWX7|UN45B_HUMAN
Protein unc-45 homolog B
Search

UNC45B

0.97	Unc-45 myosin chaperone B

0.72	GO:0061077	chaperone-mediated protein folding
0.60	GO:0002088	lens development in camera-type eye
0.58	GO:0007517	muscle organ development
0.56	GO:0048747	muscle fiber development
0.56	GO:0030239	myofibril assembly
0.55	GO:0048738	cardiac muscle tissue development
0.36	GO:0051216	cartilage development
0.36	GO:0001525	angiogenesis
0.36	GO:0008015	blood circulation

0.80	GO:0051879	Hsp90 protein binding
0.45	GO:0045296	cadherin binding

0.64	GO:0005829	cytosol
0.56	GO:0030018	Z disc
0.45	GO:0016607	nuclear speck
0.42	GO:0005794	Golgi apparatus
0.38	GO:0031672	A band
0.37	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IWX8|CHERP_HUMAN
Calcium homeostasis endoplasmic reticulum protein
Search

CHERP

0.92	calcium homeostasis endoplasmic reticulum protein isoform X2

0.62	GO:0051533	positive regulation of NFAT protein import into nucleus
0.58	GO:0006396	RNA processing
0.58	GO:0051209	release of sequestered calcium ion into cytosol
0.55	GO:0008285	negative regulation of cell proliferation
0.35	GO:0007399	nervous system development
0.34	GO:0016071	mRNA metabolic process

0.58	GO:0044325	ion channel binding
0.55	GO:0003723	RNA binding

0.55	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0033017	sarcoplasmic reticulum membrane
0.34	GO:0005654	nucleoplasm

sp|Q8IWY4|SCUB1_HUMAN
Signal peptide, CUB and EGF-like domain-containing protein 1
Search

0.84	Signal peptide, CUB domain and EGF like domain containing 1

0.45	GO:0045880	positive regulation of smoothened signaling pathway
0.44	GO:0030154	cell differentiation
0.43	GO:0051260	protein homooligomerization
0.41	GO:0007165	signal transduction
0.41	GO:0060215	primitive hemopoiesis
0.40	GO:0071773	cellular response to BMP stimulus
0.39	GO:0061061	muscle structure development
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0014706	striated muscle tissue development
0.30	GO:0022411	cellular component disassembly

0.70	GO:0005509	calcium ion binding
0.42	GO:0046982	protein heterodimerization activity
0.42	GO:0042802	identical protein binding
0.35	GO:0008289	lipid binding

0.46	GO:0009986	cell surface
0.45	GO:0005615	extracellular space
0.43	GO:0019897	extrinsic component of plasma membrane
0.42	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IWY8|ZSC29_HUMAN
Zinc finger and SCAN domain-containing protein 29
Search

0.65	Zinc finger protein 690

0.45	GO:0097659	nucleic acid-templated transcription
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.43	GO:0010467	gene expression
0.42	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.46	GO:0003700	DNA binding transcription factor activity
0.43	GO:0046872	metal ion binding

0.46

GO:0005634

nucleus

sp|Q8IWY9|CDAN1_HUMAN
Codanin-1
Search

CDAN1

0.94	Congenital dyserythropoietic anemia, type I

0.79	GO:0008156	negative regulation of DNA replication
0.76	GO:0031497	chromatin assembly
0.63	GO:0008104	protein localization
0.41	GO:0006998	nuclear envelope organization
0.36	GO:0007018	microtubule-based movement

0.38	GO:0005515	protein binding
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008289	lipid binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0005829	cytosol
0.65	GO:0012505	endomembrane system
0.60	GO:0005634	nucleus
0.54	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IWZ3|ANKH1_HUMAN
Ankyrin repeat and KH domain-containing protein 1
Search

0.83	LOW QUALITY PROTEIN: ankyrin repeat and KH domain-containing protein 1

0.43	GO:0060047	heart contraction
0.39	GO:0045087	innate immune response
0.38	GO:1900245	positive regulation of MDA-5 signaling pathway
0.38	GO:1900246	positive regulation of RIG-I signaling pathway
0.37	GO:0051151	negative regulation of smooth muscle cell differentiation
0.37	GO:0001955	blood vessel maturation
0.37	GO:0045947	negative regulation of translational initiation
0.37	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.37	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.36	GO:0042742	defense response to bacterium

0.59	GO:0003723	RNA binding
0.38	GO:0008190	eukaryotic initiation factor 4E binding
0.36	GO:0003682	chromatin binding

0.36	GO:0031965	nuclear membrane
0.35	GO:0000785	chromatin
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q8IWZ4|TRI48_HUMAN
Tripartite motif-containing protein 48
Search

0.97	Tripartite motif-containing protein 48

0.33	GO:0046597	negative regulation of viral entry into host cell
0.33	GO:0032897	negative regulation of viral transcription
0.33	GO:1902186	regulation of viral release from host cell
0.33	GO:0051091	positive regulation of DNA binding transcription factor activity
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0045087	innate immune response
0.32	GO:0016567	protein ubiquitination

0.62	GO:0008270	zinc ion binding
0.35	GO:0019901	protein kinase binding
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0016874	ligase activity
0.31	GO:0016740	transferase activity

0.45	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

GO:0016874

sp|Q8IWZ5|TRI42_HUMAN
Tripartite motif-containing protein 42
Search

TRIM42

0.97	Tripartite motif-containing protein 42

0.39

GO:0035556

intracellular signal transduction

0.63	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding

0.45

GO:0005622

intracellular

sp|Q8IWZ6|BBS7_HUMAN
Bardet-Biedl syndrome 7 protein
Search

BBS7

0.97	Bardet-Biedl syndrome 7 protein homolog

0.79	GO:1905515	non-motile cilium assembly
0.62	GO:1903929	primary palate development
0.60	GO:0048736	appendage development
0.59	GO:0007507	heart development
0.58	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.58	GO:0045444	fat cell differentiation
0.57	GO:0007224	smoothened signaling pathway
0.55	GO:0001654	eye development
0.55	GO:0008104	protein localization
0.55	GO:0007420	brain development

0.59	GO:0001103	RNA polymerase II repressing transcription factor binding
0.33	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.33	GO:0005262	calcium channel activity

0.79	GO:0034464	BBSome
0.68	GO:0036064	ciliary basal body
0.59	GO:0005930	axoneme
0.58	GO:0001750	photoreceptor outer segment
0.55	GO:0005813	centrosome
0.46	GO:0005634	nucleus
0.37	GO:0060170	ciliary membrane
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:1.5.1.5	GO:0004488
0.33	KEGG:R01220	GO:0004488

sp|Q8IWZ8|SUGP1_HUMAN
SURP and G-patch domain-containing protein 1
Search

SUGP1

0.93	SURP and G-patch domain-containing protein 1

0.63	GO:0006396	RNA processing
0.30	GO:0016071	mRNA metabolic process

0.59	GO:0003723	RNA binding
0.30	GO:0005515	protein binding

0.44	GO:0005654	nucleoplasm
0.30	GO:0032991	macromolecular complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IX01|SUGP2_HUMAN
SURP and G-patch domain-containing protein 2
Search

SUGP2

0.97	SURP and G-patch domain-containing protein 2

0.63	GO:0006396	RNA processing
0.37	GO:0016071	mRNA metabolic process

0.59

GO:0003723

RNA binding

0.61

GO:0016604

nuclear body

sp|Q8IX03|KIBRA_HUMAN
Protein KIBRA
Search

WWC1

0.92	WW and C2 domain containing 1

0.85	GO:0035331	negative regulation of hippo signaling
0.83	GO:0046621	negative regulation of organ growth
0.75	GO:0043410	positive regulation of MAPK cascade
0.74	GO:0000122	negative regulation of transcription by RNA polymerase II
0.74	GO:0016477	cell migration
0.58	GO:0032475	otolith formation
0.55	GO:0071599	otic vesicle development
0.35	GO:0005975	carbohydrate metabolic process

0.77	GO:0032947	protein complex scaffold activity
0.75	GO:0003713	transcription coactivator activity
0.74	GO:0019900	kinase binding
0.40	GO:0030674	protein binding, bridging
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.81	GO:0032587	ruffle membrane
0.75	GO:0048471	perinuclear region of cytoplasm
0.65	GO:0005829	cytosol
0.59	GO:0005634	nucleus
0.36	GO:0043234	protein complex

0.36

EC:3.2.1

GO:0004553

sp|Q8IX04|UEVLD_HUMAN
Ubiquitin-conjugating enzyme E2 variant 3
Search

UEVLD

0.95	Ubiquitin-conjugating enzyme E2 variant 3

0.65	GO:0015031	protein transport
0.60	GO:0005975	carbohydrate metabolic process
0.59	GO:0006464	cellular protein modification process
0.57	GO:0019752	carboxylic acid metabolic process
0.53	GO:0055114	oxidation-reduction process

0.66

GO:0016616

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.38

GO:0070062

extracellular exosome

0.66

EC:1.1.1

GO:0016616

sp|Q8IX05|CD302_HUMAN
CD302 antigen
Search

sp|Q8IX06|GOR_HUMAN
Putative exonuclease GOR
Search

0.64	Exonuclease GOR

0.58	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0010468	regulation of gene expression

0.62	GO:0004527	exonuclease activity
0.51	GO:0003676	nucleic acid binding
0.30	GO:0005515	protein binding

0.39	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0005737	cytoplasm
0.34	GO:0044446	intracellular organelle part

sp|Q8IX07|FOG1_HUMAN
Zinc finger protein ZFPM1
Search

ZFPM1

0.86	Zinc finger protein, multitype 1

0.62	GO:0060377	negative regulation of mast cell differentiation
0.62	GO:0060318	definitive erythrocyte differentiation
0.61	GO:0003195	tricuspid valve formation
0.61	GO:0003192	mitral valve formation
0.60	GO:0071733	transcriptional activation by promoter-enhancer looping
0.60	GO:0045403	negative regulation of interleukin-4 biosynthetic process
0.60	GO:0060319	primitive erythrocyte differentiation
0.59	GO:0030219	megakaryocyte differentiation
0.58	GO:0060413	atrial septum morphogenesis
0.58	GO:0098751	bone cell development

0.57	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0003714	transcription corepressor activity
0.36	GO:0046872	metal ion binding

0.52	GO:0017053	transcriptional repressor complex
0.50	GO:0005667	transcription factor complex
0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.30	GO:0044422	organelle part
0.30	GO:0031974	membrane-enclosed lumen

sp|Q8IX12|CCAR1_HUMAN
Cell division cycle and apoptosis regulator protein 1
Search

CCAR1

0.92	Cell division cycle and apoptosis regulator protein 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0051301	cell division
0.54	GO:0030335	positive regulation of cell migration
0.53	GO:0008284	positive regulation of cell proliferation
0.50	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0006915	apoptotic process
0.36	GO:0007049	cell cycle
0.35	GO:0043065	positive regulation of apoptotic process

0.56	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.55	GO:0001047	core promoter binding
0.55	GO:0003714	transcription corepressor activity
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.39	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005641	nuclear envelope lumen
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IX15|HOMEZ_HUMAN
Homeobox and leucine zipper protein Homez
Search

HOMEZ

0.95	Homeobox and leucine zipper protein Homez

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.47	GO:0051253	negative regulation of RNA metabolic process
0.47	GO:0010558	negative regulation of macromolecule biosynthetic process
0.47	GO:0031327	negative regulation of cellular biosynthetic process
0.36	GO:0006351	transcription, DNA-templated
0.32	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0048015	phosphatidylinositol-mediated signaling
0.32	GO:0034968	histone lysine methylation

0.55	GO:0003677	DNA binding
0.51	GO:0003714	transcription corepressor activity
0.43	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding
0.32	GO:0004519	endonuclease activity
0.32	GO:0018024	histone-lysine N-methyltransferase activity
0.32	GO:0004012	phospholipid-translocating ATPase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0004540	ribonuclease activity
0.31	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.52	GO:0031974	membrane-enclosed lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:2.1.1.43

GO:0018024

sp|Q8IX18|DHX40_HUMAN
Probable ATP-dependent RNA helicase DHX40
Search

DHX40

0.95	DEAH (Asp-Glu-Ala-His) box polypeptide 40

0.51

GO:0000398

mRNA splicing, via spliceosome

0.67	GO:0004386	helicase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008186	RNA-dependent ATPase activity
0.48	GO:0003676	nucleic acid binding
0.44	GO:0140098	catalytic activity, acting on RNA

0.51	GO:0005681	spliceosomal complex
0.39	GO:0005737	cytoplasm

sp|Q8IX19|MCEM1_HUMAN
Mast cell-expressed membrane protein 1
Search

MCEMP1

0.97	Mast cell-expressed membrane protein 1

0.46

GO:0043312

neutrophil degranulation

0.47	GO:0035579	specific granule membrane
0.47	GO:0070821	tertiary granule membrane
0.37	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q8IX21|SLF2_HUMAN
SMC5-SMC6 complex localization factor protein 2
Search

SLF2

0.97	SMC5-SMC6 complex localization factor protein 2

0.87	GO:1990166	protein localization to site of double-strand break
0.87	GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion
0.86	GO:2000781	positive regulation of double-strand break repair
0.78	GO:0031334	positive regulation of protein complex assembly
0.64	GO:0006974	cellular response to DNA damage stimulus
0.40	GO:0006259	DNA metabolic process

0.77	GO:0031625	ubiquitin protein ligase binding
0.73	GO:0032403	protein complex binding

0.83	GO:0035861	site of double-strand break
0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.45	GO:0005615	extracellular space

sp|Q8IX29|FBX16_HUMAN
F-box only protein 16
Search

FBXO16

0.97	F-box only protein 16

sp|Q8IX30|SCUB3_HUMAN
Signal peptide, CUB and EGF-like domain-containing protein 3
Search

SCUBE3

0.89	Signal peptide, CUB domain and EGF like domain containing 3

0.59	GO:0045880	positive regulation of smoothened signaling pathway
0.56	GO:0051291	protein heterooligomerization
0.54	GO:0051260	protein homooligomerization
0.48	GO:0030154	cell differentiation
0.43	GO:0007165	signal transduction
0.42	GO:0007519	skeletal muscle tissue development
0.39	GO:0022617	extracellular matrix disassembly
0.36	GO:0007512	adult heart development
0.36	GO:0003158	endothelium development
0.35	GO:0007596	blood coagulation

0.70	GO:0005509	calcium ion binding
0.39	GO:0046982	protein heterodimerization activity
0.39	GO:0042802	identical protein binding

0.55	GO:0009986	cell surface
0.47	GO:0005615	extracellular space
0.43	GO:0005886	plasma membrane
0.39	GO:0019898	extrinsic component of membrane
0.39	GO:0098552	side of membrane

sp|Q8IX90|SKA3_HUMAN
Spindle and kinetochore-associated protein 3
Search

SKA3

0.97	Spindle and kinetochore associated complex subunit 3

0.73	GO:0007059	chromosome segregation
0.63	GO:0031110	regulation of microtubule polymerization or depolymerization
0.58	GO:0000278	mitotic cell cycle
0.40	GO:0051301	cell division

0.35	GO:0005515	protein binding
0.35	GO:0019706	protein-cysteine S-palmitoyltransferase activity

0.82	GO:0000940	condensed chromosome outer kinetochore
0.62	GO:0005876	spindle microtubule
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

GO:0019706

sp|Q8IX94|CTGE4_HUMAN
cTAGE family member 4
Search

0.83	Cutaneous T-cell lymphoma-associated antigen 1

0.30

GO:0044425

membrane part

sp|Q8IX95|CTGE3_HUMAN
Putative cTAGE family member 3
Search

0.12	Putative cTAGE family member 3

0.30

GO:0044425

membrane part

sp|Q8IXA5|SACA3_HUMAN
Sperm acrosome membrane-associated protein 3
Search

0.96	LOW QUALITY PROTEIN: sperm acrosome membrane-associated protein 3

0.82	GO:0009566	fertilization
0.66	GO:0045026	plasma membrane fusion
0.64	GO:0009988	cell-cell recognition
0.62	GO:0022412	cellular process involved in reproduction in multicellular organism
0.54	GO:0050830	defense response to Gram-positive bacterium
0.53	GO:0050829	defense response to Gram-negative bacterium
0.50	GO:0016998	cell wall macromolecule catabolic process
0.42	GO:0042117	monocyte activation
0.42	GO:0043032	positive regulation of macrophage activation
0.41	GO:0050766	positive regulation of phagocytosis

0.79	GO:0003796	lysozyme activity
0.38	GO:0005515	protein binding

0.72	GO:0002080	acrosomal membrane
0.71	GO:0043159	acrosomal matrix
0.49	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.79

EC:3.2.1.17

GO:0003796

sp|Q8IXB1|DJC10_HUMAN
DnaJ homolog subfamily C member 10
Search

DNAJC10

0.91	DnaJ like protein subfamily C member 10

0.79	GO:0034975	protein folding in endoplasmic reticulum
0.71	GO:0030433	ubiquitin-dependent ERAD pathway
0.69	GO:0045454	cell redox homeostasis
0.65	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.59	GO:0032781	positive regulation of ATPase activity
0.57	GO:0001933	negative regulation of protein phosphorylation
0.50	GO:0055114	oxidation-reduction process
0.36	GO:0007018	microtubule-based movement

0.66	GO:0015036	disulfide oxidoreductase activity
0.66	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.65	GO:0030544	Hsp70 protein binding
0.65	GO:0051787	misfolded protein binding
0.64	GO:0051117	ATPase binding
0.59	GO:0001671	ATPase activator activity
0.59	GO:0051087	chaperone binding
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding
0.35	GO:0016853	isomerase activity

0.72	GO:0005788	endoplasmic reticulum lumen
0.67	GO:0034663	endoplasmic reticulum chaperone complex
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:1.8.4

GO:0016671

sp|Q8IXB3|TUSC5_HUMAN
Tumor suppressor candidate 5
Search

TUSC5

0.97	Tumor suppressor candidate 5 transcript variant 1

0.70	GO:0009607	response to biotic stimulus
0.70	GO:0044381	glucose import in response to insulin stimulus
0.69	GO:0099638	endosome to plasma membrane protein transport
0.64	GO:0045026	plasma membrane fusion
0.43	GO:0048675	axon extension

0.35

GO:0005515

protein binding

0.59	GO:0030659	cytoplasmic vesicle membrane
0.46	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IXE1|OR4N5_HUMAN
Olfactory receptor 4N5
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IXF0|NPAS3_HUMAN
Neuronal PAS domain-containing protein 3
Search

NPAS3

0.95	Neuronal PAS domain-containing protein 3

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.52	GO:0006351	transcription, DNA-templated
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:0032502	developmental process
0.38	GO:0042711	maternal behavior
0.37	GO:0001964	startle response
0.36	GO:0007626	locomotory behavior

0.62	GO:0046983	protein dimerization activity
0.43	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.37	GO:0003677	DNA binding

0.57	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

sp|Q8IXF9|AQ12A_HUMAN
Aquaporin-12A
Search

0.67

Aquaporin

0.54	GO:0055085	transmembrane transport
0.35	GO:0071391	cellular response to estrogen stimulus
0.34	GO:0042981	regulation of apoptotic process
0.34	GO:0006468	protein phosphorylation

0.67	GO:0015267	channel activity
0.35	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.35

GO:0004674

sp|Q8IXH6|T53I2_HUMAN
Tumor protein p53-inducible nuclear protein 2
Search

TP53INP2

0.90	Tumor protein p53-inducible nuclear protein 2

0.75	GO:0010508	positive regulation of autophagy
0.70	GO:0045893	positive regulation of transcription, DNA-templated
0.61	GO:0000045	autophagosome assembly
0.60	GO:0001649	osteoblast differentiation
0.59	GO:1903828	negative regulation of cellular protein localization
0.59	GO:0001894	tissue homeostasis
0.53	GO:0006511	ubiquitin-dependent protein catabolic process
0.39	GO:0008285	negative regulation of cell proliferation
0.38	GO:0035076	ecdysone receptor-mediated signaling pathway
0.36	GO:0006357	regulation of transcription by RNA polymerase II

0.58	GO:0043130	ubiquitin binding
0.38	GO:0035258	steroid hormone receptor binding
0.38	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.33	GO:0001106	RNA polymerase II transcription corepressor activity
0.33	GO:0019212	phosphatase inhibitor activity
0.33	GO:0003682	chromatin binding
0.33	GO:0016209	antioxidant activity
0.32	GO:0016301	kinase activity

0.62	GO:0005776	autophagosome
0.51	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0000428	DNA-directed RNA polymerase complex

sp|Q8IXH7|NELFD_HUMAN
Negative elongation factor C/D
Search

NELFCD

0.94	Negative elongation factor D

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.55	GO:0006414	translational elongation
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0050434	positive regulation of viral transcription

0.56	GO:0003746	translation elongation factor activity
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043234	protein complex
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q8IXH8|CAD26_HUMAN
Cadherin-like protein 26
Search

CDH26

0.97	Cadherin 26, tandem duplicate 1

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0072137	condensed mesenchymal cell proliferation
0.37	GO:0007166	cell surface receptor signaling pathway
0.37	GO:0048731	system development
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007267	cell-cell signaling
0.34	GO:0022405	hair cycle process
0.34	GO:0071773	cellular response to BMP stimulus
0.34	GO:0009913	epidermal cell differentiation
0.33	GO:0060471	cortical granule exocytosis

0.70	GO:0005509	calcium ion binding
0.37	GO:0004930	G-protein coupled receptor activity
0.32	GO:0004725	protein tyrosine phosphatase activity

0.55	GO:0005886	plasma membrane
0.34	GO:0030057	desmosome
0.30	GO:0016021	integral component of membrane

0.32

EC:3.1.3.48

GO:0004725

sp|Q8IXI1|MIRO2_HUMAN
Mitochondrial Rho GTPase 2
Search

RHOT2

0.72	Mitochondrial Rho GTPase

0.71	GO:0007005	mitochondrion organization
0.60	GO:1905710	positive regulation of membrane permeability
0.60	GO:0047497	mitochondrion transport along microtubule
0.56	GO:0097190	apoptotic signaling pathway
0.54	GO:0006839	mitochondrial transport
0.49	GO:0019725	cellular homeostasis
0.49	GO:0061024	membrane organization
0.37	GO:0034640	establishment of mitochondrion localization by microtubule attachment
0.37	GO:1902513	regulation of organelle transport along microtubule
0.36	GO:0046928	regulation of neurotransmitter secretion

0.68	GO:0005509	calcium ion binding
0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.78	GO:0031307	integral component of mitochondrial outer membrane
0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.34	GO:0019866	organelle inner membrane
0.33	GO:0005886	plasma membrane
0.33	GO:0005840	ribosome

sp|Q8IXI2|MIRO1_HUMAN
Mitochondrial Rho GTPase 1
Search

RHOT1

0.70	Mitochondrial Rho GTPase

0.73	GO:0007005	mitochondrion organization
0.53	GO:1905710	positive regulation of membrane permeability
0.53	GO:0047497	mitochondrion transport along microtubule
0.50	GO:0097190	apoptotic signaling pathway
0.49	GO:0006839	mitochondrial transport
0.45	GO:0019725	cellular homeostasis
0.45	GO:0061024	membrane organization
0.40	GO:0034640	establishment of mitochondrion localization by microtubule attachment
0.39	GO:1902513	regulation of organelle transport along microtubule
0.38	GO:0046928	regulation of neurotransmitter secretion

0.69	GO:0005509	calcium ion binding
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.80	GO:0031307	integral component of mitochondrial outer membrane
0.33	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.32	GO:0005886	plasma membrane

sp|Q8IXJ6|SIR2_HUMAN
NAD-dependent protein deacetylase sirtuin-2
Search

SIRT2

0.60	NAD-dependent protein deacetylase

0.77	GO:0016575	histone deacetylation
0.59	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
0.58	GO:0061433	cellular response to caloric restriction
0.58	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.58	GO:0090042	tubulin deacetylation
0.57	GO:1900195	positive regulation of oocyte maturation
0.57	GO:0034983	peptidyl-lysine deacetylation
0.57	GO:0071872	cellular response to epinephrine stimulus
0.57	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.57	GO:1900425	negative regulation of defense response to bacterium

0.79	GO:0017136	NAD-dependent histone deacetylase activity
0.77	GO:0070403	NAD+ binding
0.61	GO:0008270	zinc ion binding
0.58	GO:0042903	tubulin deacetylase activity
0.57	GO:0034739	histone deacetylase activity (H4-K16 specific)
0.55	GO:0035035	histone acetyltransferase binding
0.53	GO:0042826	histone deacetylase binding
0.52	GO:0043130	ubiquitin binding
0.51	GO:0003682	chromatin binding
0.48	GO:0008134	transcription factor binding

0.57	GO:0033010	paranodal junction
0.56	GO:0043220	Schmidt-Lanterman incisure
0.55	GO:0072687	meiotic spindle
0.54	GO:0043204	perikaryon
0.53	GO:0030496	midbody
0.53	GO:0005814	centriole
0.52	GO:0072686	mitotic spindle
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005813	centrosome
0.49	GO:0005730	nucleolus

0.35

EC:2.4.2.30

GO:0003950

sp|Q8IXJ9|ASXL1_HUMAN
Putative Polycomb group protein ASXL1
Search

ASXL1

0.95	Additional sex combs like 1, transcriptional regulator

0.72	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway
0.72	GO:0048386	positive regulation of retinoic acid receptor signaling pathway
0.71	GO:0048539	bone marrow development
0.71	GO:0060430	lung saccule development
0.69	GO:0035521	monoubiquitinated histone deubiquitination
0.68	GO:0045599	negative regulation of fat cell differentiation
0.67	GO:0048538	thymus development
0.67	GO:0032526	response to retinoic acid
0.64	GO:0003007	heart morphogenesis
0.63	GO:0030097	hemopoiesis

0.71	GO:0042975	peroxisome proliferator activated receptor binding
0.69	GO:0042974	retinoic acid receptor binding
0.62	GO:0003713	transcription coactivator activity
0.55	GO:0003677	DNA binding

0.71

GO:0035517

PR-DUB complex

sp|Q8IXK0|PHC2_HUMAN
Polyhomeotic-like protein 2
Search

PHC2

0.94	Polyhomeotic homolog 2

0.69

GO:0007283

spermatogenesis

0.66	GO:0042802	identical protein binding
0.63	GO:0008270	zinc ion binding

0.77	GO:0035102	PRC1 complex
0.71	GO:0000792	heterochromatin
0.63	GO:0005654	nucleoplasm

sp|Q8IXK2|GLT12_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 12
Search

GALNT12

0.64	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0006486	protein glycosylation
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.32	GO:0005975	carbohydrate metabolic process

0.68	GO:0030246	carbohydrate binding
0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0046872	metal ion binding

0.72	GO:0000139	Golgi membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0016757

sp|Q8IXL6|FA20C_HUMAN
Extracellular serine/threonine protein kinase FAM20C
Search

FAM20C

0.88	Dentin matrix protein 4

0.56	GO:0036179	osteoclast maturation
0.56	GO:0006468	protein phosphorylation
0.56	GO:0031214	biomineral tissue development
0.55	GO:0071895	odontoblast differentiation
0.53	GO:0097187	dentinogenesis
0.53	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.52	GO:0030501	positive regulation of bone mineralization
0.52	GO:0045669	positive regulation of osteoblast differentiation
0.52	GO:0097186	amelogenesis
0.46	GO:0051174	regulation of phosphorus metabolic process

0.61	GO:0004674	protein serine/threonine kinase activity
0.49	GO:0030145	manganese ion binding
0.46	GO:0005509	calcium ion binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0005515	protein binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005615	extracellular space
0.49	GO:0005794	Golgi apparatus
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005634	nucleus
0.34	GO:0031301	integral component of organelle membrane
0.33	GO:0098796	membrane protein complex
0.33	GO:0019866	organelle inner membrane

0.61

GO:0004674

sp|Q8IXL7|MSRB3_HUMAN
Methionine-R-sulfoxide reductase B3
Search

MSRB3

0.97	Methionine sulfoxide reductase B3 transcript variant 1

0.73	GO:0030091	protein repair
0.67	GO:0006979	response to oxidative stress
0.51	GO:0055114	oxidation-reduction process
0.45	GO:0048839	inner ear development

0.74	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.48	GO:0008270	zinc ion binding
0.39	GO:0033745	L-methionine-(R)-S-oxide reductase activity
0.34	GO:0005515	protein binding

0.51	GO:0005783	endoplasmic reticulum
0.46	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol
0.34	GO:0009570	chloroplast stroma
0.30	GO:0031224	intrinsic component of membrane

0.74	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.74	KEGG:R07607	GO:0033743

sp|Q8IXL9|IQCF2_HUMAN
IQ domain-containing protein F2
Search

0.97	IQ domain-containing protein F2

0.62	GO:2000344	positive regulation of acrosome reaction
0.61	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.35	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0060216	definitive hemopoiesis
0.34	GO:0009059	macromolecule biosynthetic process

0.75	GO:0005516	calmodulin binding
0.36	GO:0003735	structural constituent of ribosome
0.34	GO:0003676	nucleic acid binding

0.64	GO:0001669	acrosomal vesicle
0.36	GO:0005840	ribosome
0.34	GO:0031514	motile cilium
0.30	GO:0016020	membrane

sp|Q8IXM2|BAP18_HUMAN
Chromatin complexes subunit BAP18
Search

0.94	Chromatin complexes subunit BAP18

0.37

GO:0016569

covalent chromatin modification

0.53	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.84	GO:0016589	NURF complex
0.82	GO:0071339	MLL1 complex
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IXM3|RM41_HUMAN
39S ribosomal protein L41, mitochondrial
Search

MRPL41

0.96	Mitochondrial ribosomal protein L41

0.49	GO:0043043	peptide biosynthetic process
0.46	GO:0044267	cellular protein metabolic process
0.45	GO:0010467	gene expression
0.44	GO:0009059	macromolecule biosynthetic process
0.43	GO:0006915	apoptotic process
0.40	GO:0007049	cell cycle
0.36	GO:0043624	cellular protein complex disassembly
0.33	GO:0006633	fatty acid biosynthetic process
0.32	GO:0036211	protein modification process
0.32	GO:0016310	phosphorylation

0.51	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0005762	mitochondrial large ribosomal subunit
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004674

sp|Q8IXM6|NRM_HUMAN
Nurim
Search

NRM

0.97	Nurim (nuclear envelope membrane protein)

0.37

GO:0005515

protein binding

0.68	GO:0031965	nuclear membrane
0.43	GO:0019866	organelle inner membrane
0.39	GO:0005652	nuclear lamina
0.30	GO:0044425	membrane part

sp|Q8IXM7|OD3L1_HUMAN
Outer dense fiber protein 3-like protein 1
Search

ODF3L1

0.96	Outer dense fiber of sperm tails 3 like 1

0.56	GO:0005881	cytoplasmic microtubule
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IXN7|RIMKA_HUMAN
N-acetylaspartylglutamate synthase A
Search

RIMKLA

0.97	N-acetylaspartyl-glutamate synthetase A

0.60	GO:0006464	cellular protein modification process
0.34	GO:0008652	cellular amino acid biosynthetic process

0.69	GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0072591	citrate-L-glutamate ligase activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding

0.41

GO:0005737

cytoplasm

sp|Q8IXP5|CK053_HUMAN
Uncharacterized protein C11orf53
Search

sp|Q8IXQ3|CI040_HUMAN
Uncharacterized protein C9orf40
Search

sp|Q8IXQ4|GPAM1_HUMAN
GPALPP motifs-containing protein 1
Search

GPALPP1

0.95	GPALPP motifs-containing protein 1

0.51	GO:0006367	transcription initiation from RNA polymerase II promoter
0.44	GO:0032049	cardiolipin biosynthetic process
0.41	GO:0045859	regulation of protein kinase activity

0.44	GO:0004605	phosphatidate cytidylyltransferase activity
0.43	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity

0.53	GO:0005674	transcription factor TFIIF complex
0.41	GO:0016592	mediator complex
0.30	GO:0016020	membrane

0.44

EC:2.7.7.41

GO:0004605

sp|Q8IXQ5|KLHL7_HUMAN
Kelch-like protein 7
Search

KLHL7

0.96	Kelch like family member 7

0.73	GO:0016567	protein ubiquitination
0.32	GO:0006412	translation

0.51	GO:0042803	protein homodimerization activity
0.44	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003735	structural constituent of ribosome

0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.53	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.32	GO:0005840	ribosome

0.44

GO:0004842

sp|Q8IXQ6|PARP9_HUMAN
Poly [ADP-ribose] polymerase 9
Search

PARP9

0.54	Poly [ADP-ribose] polymerase

0.62	GO:0060332	positive regulation of response to interferon-gamma
0.61	GO:0035563	positive regulation of chromatin binding
0.60	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining
0.60	GO:0060334	regulation of interferon-gamma-mediated signaling pathway
0.60	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.59	GO:0002230	positive regulation of defense response to virus by host
0.59	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.57	GO:0006471	protein ADP-ribosylation
0.57	GO:1900182	positive regulation of protein localization to nucleus
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.63	GO:0072570	ADP-D-ribose binding
0.62	GO:0097677	STAT family protein binding
0.58	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.55	GO:0042393	histone binding
0.55	GO:0044389	ubiquitin-like protein ligase binding
0.52	GO:0004857	enzyme inhibitor activity
0.37	GO:0070403	NAD+ binding
0.36	GO:0061608	nuclear import signal receptor activity
0.34	GO:0008565	protein transporter activity

0.57	GO:0090734	site of DNA damage
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.45	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.81

EC:2.4.2.30

GO:0003950

sp|Q8IXQ8|PDZD9_HUMAN
PDZ domain-containing protein 9
Search

PDZD9

0.97	PDZ domain-containing protein 9

sp|Q8IXQ9|ETKMT_HUMAN
Electron transfer flavoprotein beta subunit lysine methyltransferase
Search

ETFBKMT

0.97	Electron transfer flavoprotein beta subunit lysine methyltransferase

0.67	GO:1904733	negative regulation of electron transfer activity
0.67	GO:1904736	negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.62	GO:0018023	peptidyl-lysine trimethylation
0.33	GO:0006414	translational elongation

0.61	GO:0008168	methyltransferase activity
0.56	GO:0031072	heat shock protein binding
0.46	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0003735	structural constituent of ribosome

0.55	GO:0005759	mitochondrial matrix
0.46	GO:0043234	protein complex
0.35	GO:0005840	ribosome

0.61

GO:0008168

sp|Q8IXR5|F178B_HUMAN
Protein FAM178B
Search

0.52	GO:0008270	zinc ion binding
0.38	GO:0019901	protein kinase binding

0.40	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q8IXR9|CL056_HUMAN
Uncharacterized protein C12orf56
Search

0.42

GO:0016884

carbon-nitrogen ligase activity, with glutamine as amido-N-donor

0.42

EC:6.3.5

GO:0016884

sp|Q8IXS0|F217A_HUMAN
Protein FAM217A
Search

sp|Q8IXS2|CCD65_HUMAN
Coiled-coil domain-containing protein 65
Search

CCDC65

0.91	Coiled-coil domain-containing protein 65

0.86	GO:0003352	regulation of cilium movement
0.76	GO:0060271	cilium assembly
0.34	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.32	GO:0006508	proteolysis

0.35	GO:0003723	RNA binding
0.34	GO:0004521	endoribonuclease activity
0.33	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.36	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IXS6|PALM2_HUMAN
Paralemmin-2
Search

PALM2

0.95	Paralemmin

0.69	GO:0008360	regulation of cell shape
0.42	GO:0071257	cellular response to electrical stimulus
0.42	GO:0060074	synapse maturation
0.42	GO:0007194	negative regulation of adenylate cyclase activity
0.42	GO:0051491	positive regulation of filopodium assembly
0.42	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.41	GO:0072659	protein localization to plasma membrane
0.41	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.38	GO:0007010	cytoskeleton organization
0.37	GO:0016310	phosphorylation

0.43	GO:0031750	D3 dopamine receptor binding
0.38	GO:0016301	kinase activity

0.42	GO:0031527	filopodium membrane
0.41	GO:0014069	postsynaptic density
0.41	GO:0044309	neuron spine
0.36	GO:0016327	apicolateral plasma membrane
0.36	GO:0097060	synaptic membrane
0.36	GO:0005634	nucleus
0.36	GO:0016323	basolateral plasma membrane
0.36	GO:0030425	dendrite
0.36	GO:0030424	axon
0.35	GO:0044306	neuron projection terminus

sp|Q8IXS8|F126B_HUMAN
Protein FAM126B
Search

0.79	Putative beta-catenin-tcf/lef signaling pathway component drctnnb1a

0.40	GO:0072659	protein localization to plasma membrane
0.38	GO:0046854	phosphatidylinositol phosphorylation
0.37	GO:0042552	myelination
0.36	GO:0006260	DNA replication

0.36

GO:0005515

protein binding

0.45	GO:0005622	intracellular
0.40	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part
0.34	GO:0043227	membrane-bounded organelle

sp|Q8IXT1|DDIAS_HUMAN
DNA damage-induced apoptosis suppressor protein
Search

DDIAS

0.97	DNA damage induced apoptosis suppressor

0.87	GO:0097752	regulation of DNA stability
0.85	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.49	GO:0007050	cell cycle arrest
0.46	GO:0006915	apoptotic process
0.44	GO:2000270	negative regulation of fibroblast apoptotic process
0.44	GO:0071447	cellular response to hydroperoxide
0.43	GO:0071480	cellular response to gamma radiation
0.42	GO:0034644	cellular response to UV
0.42	GO:0007286	spermatid development
0.41	GO:0030097	hemopoiesis

0.36

GO:0003735

structural constituent of ribosome

0.41	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q8IXT2|DMRTD_HUMAN
Doublesex- and mab-3-related transcription factor C2
Search

DMRTC2

0.97	Doublesex- and mab-3-related transcription factor C2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0007290	spermatid nucleus elongation
0.47	GO:1900114	positive regulation of histone H3-K9 trimethylation
0.47	GO:1900111	positive regulation of histone H3-K9 dimethylation
0.46	GO:0007141	male meiosis I
0.43	GO:0007548	sex differentiation
0.43	GO:2000287	positive regulation of myotome development
0.42	GO:0014807	regulation of somitogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0046872	metal ion binding
0.47	GO:0042803	protein homodimerization activity
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.35	GO:0003735	structural constituent of ribosome
0.32	GO:0043015	gamma-tubulin binding
0.32	GO:0005544	calcium-dependent phospholipid binding
0.32	GO:0008081	phosphoric diester hydrolase activity

0.61	GO:0005634	nucleus
0.46	GO:0001741	XY body
0.34	GO:0005840	ribosome
0.33	GO:0044430	cytoskeletal part
0.32	GO:0045111	intermediate filament cytoskeleton
0.32	GO:0099512	supramolecular fiber
0.32	GO:0015630	microtubule cytoskeleton
0.30	GO:0016021	integral component of membrane

0.32

EC:3.1.4

GO:0008081

sp|Q8IXT5|RB12B_HUMAN
RNA-binding protein 12B
Search

RBM12B

0.92	RNA binding motif protein 12B

0.31

GO:0030001

metal ion transport

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.31	GO:0046872	metal ion binding

0.36	GO:0005654	nucleoplasm
0.32	GO:0031965	nuclear membrane
0.32	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0044425	membrane part

sp|Q8IXU6|S35F2_HUMAN
Solute carrier family 35 member F2
Search

SLC35F2

0.97	Info solute carrier family 35, member F2, like

0.54

GO:0055085

transmembrane transport

0.56

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|Q8IXV7|KLD8B_HUMAN
Kelch domain-containing protein 8B
Search

KLHDC8B

0.97	LOW QUALITY PROTEIN: kelch domain-containing protein 8B

0.60	GO:0016567	protein ubiquitination
0.43	GO:0051301	cell division
0.43	GO:0007049	cell cycle

0.60

GO:0004842

ubiquitin-protein transferase activity

0.67	GO:0031463	Cul3-RING ubiquitin ligase complex
0.62	GO:0005829	cytosol
0.49	GO:0030496	midbody
0.30	GO:0031224	intrinsic component of membrane

0.60

GO:0004842

sp|Q8IXW0|LMTD2_HUMAN
Lamin tail domain-containing protein 2
Search

LMNTD2

0.97	Lamin tail domain-containing protein 2

0.86

GO:0048026

positive regulation of mRNA splicing, via spliceosome

sp|Q8IXW5|RPAP2_HUMAN
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Search

RPAP2

0.51	Ubiquitin carboxyl-terminal hydrolase

0.85	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain
0.83	GO:0009301	snRNA transcription
0.39	GO:0006366	transcription by RNA polymerase II
0.37	GO:0006511	ubiquitin-dependent protein catabolic process
0.33	GO:0006569	tryptophan catabolic process
0.33	GO:0009435	NAD biosynthetic process

0.85	GO:0008420	CTD phosphatase activity
0.40	GO:0046872	metal ion binding
0.38	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.37	GO:0005515	protein binding
0.34	GO:0030429	kynureninase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0003676	nucleic acid binding

0.71	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.68	GO:0005730	nucleolus
0.64	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.7.1.3

GO:0030429

sp|Q8IXX5|T183A_HUMAN
Transmembrane protein 183A
Search

TMEM183A

0.93	Transmembrane domain-containing protein (Fragment)

0.33

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q8IXY8|PPIL6_HUMAN
Peptidyl-prolyl cis-trans isomerase-like 6
Search

PPIL6

0.39	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.47	GO:0006457	protein folding
0.32	GO:0006367	transcription initiation from RNA polymerase II promoter
0.32	GO:0034605	cellular response to heat
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0007018	microtubule-based movement

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0016018	cyclosporin A binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding
0.32	GO:0003777	microtubule motor activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0005802	trans-Golgi network
0.33	GO:0005829	cytosol
0.33	GO:0005768	endosome
0.32	GO:0005672	transcription factor TFIIA complex
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.72

EC:5.2.1.8

GO:0003755

sp|Q8IXZ2|ZC3H3_HUMAN
Zinc finger CCCH domain-containing protein 3
Search

ZC3H3

0.88	Zinc finger CCCH domain-containing protein 3

0.66	GO:0010793	regulation of mRNA export from nucleus
0.64	GO:0032927	positive regulation of activin receptor signaling pathway
0.63	GO:0016973	poly(A)+ mRNA export from nucleus
0.61	GO:0006378	mRNA polyadenylation
0.46	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.63	GO:0070412	R-SMAD binding
0.54	GO:0046872	metal ion binding
0.46	GO:0004521	endoribonuclease activity
0.41	GO:0003723	RNA binding
0.36	GO:0003677	DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.60

GO:0005847

mRNA cleavage and polyadenylation specificity factor complex

sp|Q8IXZ3|SP8_HUMAN
Transcription factor Sp8
Search

0.96	Specificity protein 8

0.55	GO:0030326	embryonic limb morphogenesis
0.50	GO:0009954	proximal/distal pattern formation
0.48	GO:0009953	dorsal/ventral pattern formation
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0035118	embryonic pectoral fin morphogenesis
0.44	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.38	GO:0007480	imaginal disc-derived leg morphogenesis
0.37	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0046872	metal ion binding

0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q8IY17|PLPL6_HUMAN
Neuropathy target esterase
Search

PNPLA6

0.93	LOW QUALITY PROTEIN: neuropathy target esterase

0.81	GO:0046470	phosphatidylcholine metabolic process
0.71	GO:0016042	lipid catabolic process
0.44	GO:0032502	developmental process
0.40	GO:0030514	negative regulation of BMP signaling pathway
0.40	GO:0032501	multicellular organismal process
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.34	GO:0046434	organophosphate catabolic process
0.33	GO:0044248	cellular catabolic process

0.81	GO:0004622	lysophospholipase activity
0.35	GO:0030507	spectrin binding
0.34	GO:0005516	calmodulin binding
0.34	GO:0008017	microtubule binding

0.43	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.34	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.81

EC:3.1.1.5

GO:0004622

sp|Q8IY18|SMC5_HUMAN
Structural maintenance of chromosomes protein 5
Search

0.78	GO:0007062	sister chromatid cohesion
0.77	GO:0000724	double-strand break repair via homologous recombination
0.65	GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion
0.62	GO:0090398	cellular senescence
0.61	GO:0000722	telomere maintenance via recombination
0.38	GO:0006303	double-strand break repair via nonhomologous end joining
0.37	GO:0051301	cell division
0.32	GO:0043043	peptide biosynthetic process
0.31	GO:0044267	cellular protein metabolic process
0.31	GO:0010467	gene expression

0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.81	GO:0030915	Smc5-Smc6 complex
0.64	GO:0035061	interchromatin granule
0.61	GO:0016605	PML body
0.59	GO:0035861	site of double-strand break
0.58	GO:0000781	chromosome, telomeric region
0.57	GO:0016607	nuclear speck
0.54	GO:0030054	cell junction
0.41	GO:0000803	sex chromosome
0.36	GO:0055044	symplast
0.32	GO:0005840	ribosome

sp|Q8IY21|DDX60_HUMAN
Probable ATP-dependent RNA helicase DDX60
Search

DDX60

0.96	DEAD-box helicase 60 like

0.73	GO:1900245	positive regulation of MDA-5 signaling pathway
0.72	GO:1900246	positive regulation of RIG-I signaling pathway
0.63	GO:0009615	response to virus
0.62	GO:0002252	immune effector process
0.61	GO:0098542	defense response to other organism

0.64	GO:0003727	single-stranded RNA binding
0.61	GO:0003725	double-stranded RNA binding
0.58	GO:0003690	double-stranded DNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0004386	helicase activity

0.63	GO:0045111	intermediate filament cytoskeleton
0.56	GO:0005829	cytosol

sp|Q8IY22|CMIP_HUMAN
C-Maf-inducing protein
Search

CMIP

0.97	C-Maf-inducing protein isoform C-Mip

0.37

GO:0005515

protein binding

0.69	GO:0005654	nucleoplasm
0.68	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IY26|PLPP6_HUMAN
Phospholipid phosphatase 6
Search

PLPP6

0.93	Phospholipid phosphatase 6

0.68	GO:0046839	phospholipid dephosphorylation
0.47	GO:0010832	negative regulation of myotube differentiation
0.40	GO:0006695	cholesterol biosynthetic process

0.74

GO:0042577

lipid phosphatase activity

0.43	GO:0005635	nuclear envelope
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IY31|IFT20_HUMAN
Intraflagellar transport protein 20 homolog
Search

IFT20

0.96	Intraflagellar transport protein 20

0.59	GO:0036372	opsin transport
0.58	GO:0051642	centrosome localization
0.58	GO:0061512	protein localization to cilium
0.57	GO:0035845	photoreceptor cell outer segment organization
0.56	GO:0042073	intraciliary transport
0.56	GO:0090102	cochlea development
0.56	GO:0034067	protein localization to Golgi apparatus
0.56	GO:0060122	inner ear receptor cell stereocilium organization
0.56	GO:0008542	visual learning
0.56	GO:2000785	regulation of autophagosome assembly

0.59	GO:0002046	opsin binding
0.54	GO:0017137	Rab GTPase binding

0.77	GO:0031514	motile cilium
0.59	GO:1902636	kinociliary basal body
0.57	GO:0044292	dendrite terminus
0.57	GO:0030992	intraciliary transport particle B
0.56	GO:0097546	ciliary base
0.56	GO:0005814	centriole
0.56	GO:0032391	photoreceptor connecting cilium
0.55	GO:0032420	stereocilium
0.55	GO:0005902	microvillus
0.55	GO:0001750	photoreceptor outer segment

sp|Q8IY33|MILK2_HUMAN
MICAL-like protein 2
Search

MICALL2

0.83	MICAL like 2

0.84	GO:0032456	endocytic recycling
0.64	GO:1903955	positive regulation of protein targeting to mitochondrion
0.61	GO:0070830	bicellular tight junction assembly
0.61	GO:0034446	substrate adhesion-dependent cell spreading
0.59	GO:0030041	actin filament polymerization
0.57	GO:0031175	neuron projection development
0.55	GO:0031532	actin cytoskeleton reorganization
0.39	GO:1990126	retrograde transport, endosome to plasma membrane
0.39	GO:0036010	protein localization to endosome
0.39	GO:0097320	plasma membrane tubulation

0.81	GO:0017137	Rab GTPase binding
0.66	GO:0031005	filamin binding
0.59	GO:0042805	actinin binding
0.56	GO:0051015	actin filament binding
0.52	GO:0046872	metal ion binding
0.39	GO:0070300	phosphatidic acid binding
0.38	GO:0045296	cadherin binding
0.37	GO:0042802	identical protein binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003743	translation initiation factor activity

0.60	GO:0097517	contractile actin filament bundle
0.60	GO:0042641	actomyosin
0.60	GO:0055037	recycling endosome
0.58	GO:0005923	bicellular tight junction
0.44	GO:0005886	plasma membrane
0.42	GO:0043005	neuron projection
0.39	GO:0005829	cytosol
0.38	GO:0005770	late endosome
0.37	GO:0010008	endosome membrane
0.37	GO:0019898	extrinsic component of membrane

sp|Q8IY34|S15A3_HUMAN
Solute carrier family 15 member 3
Search

SLC15A3

0.96	Solute carrier family 15 (oligopeptide transporter), member 4

0.66	GO:0006857	oligopeptide transport
0.54	GO:0055085	transmembrane transport
0.39	GO:0015031	protein transport
0.35	GO:0006812	cation transport
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0015802	basic amino acid transport
0.34	GO:0030163	protein catabolic process
0.34	GO:0045117	azole transport
0.34	GO:0015807	L-amino acid transport
0.33	GO:0015893	drug transport

0.56	GO:0022857	transmembrane transporter activity
0.37	GO:0015197	peptide transporter activity
0.35	GO:0005515	protein binding

0.43	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.36	GO:0044446	intracellular organelle part
0.35	GO:0044444	cytoplasmic part
0.34	GO:0012506	vesicle membrane
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IY37|DHX37_HUMAN
Probable ATP-dependent RNA helicase DHX37
Search

DHX37

0.97	DEAH (Asp-Glu-Ala-His) box polypeptide 37

0.46	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.42	GO:0006396	RNA processing
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0042254	ribosome biogenesis

0.67	GO:0004386	helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0003676	nucleic acid binding
0.47	GO:0008186	RNA-dependent ATPase activity
0.41	GO:0140098	catalytic activity, acting on RNA

0.46	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

sp|Q8IY42|CD019_HUMAN
Uncharacterized protein C4orf19
Search

0.39

GO:0005515

protein binding

0.75	GO:0030054	cell junction
0.70	GO:0005654	nucleoplasm

sp|Q8IY45|AMN1_HUMAN
Protein AMN1 homolog
Search

AMN1

0.97	Antagonist of mitotic exit network 1

0.43

GO:0016032

viral process

0.42

GO:0016874

ligase activity

0.42

GO:0016874

sp|Q8IY47|KBTB2_HUMAN
Kelch repeat and BTB domain-containing protein 2
Search

KBTBD2

0.96	Kelch repeat and BTB domain-containing protein 2

0.71

GO:0016567

protein ubiquitination

0.72

GO:0004842

ubiquitin-protein transferase activity

0.82	GO:0031463	Cul3-RING ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0004842

sp|Q8IY49|PAQRA_HUMAN
Monocyte to macrophage differentiation factor 2
Search

MMD2

0.72	Monocyte to macrophage differentiation associated

0.61	GO:0045666	positive regulation of neuron differentiation
0.60	GO:0046579	positive regulation of Ras protein signal transduction
0.59	GO:0045860	positive regulation of protein kinase activity
0.56	GO:0032880	regulation of protein localization
0.50	GO:0006468	protein phosphorylation
0.45	GO:0019835	cytolysis
0.44	GO:0003007	heart morphogenesis
0.37	GO:0007165	signal transduction

0.50

GO:0004672

protein kinase activity

0.56	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005794	Golgi apparatus
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

sp|Q8IY50|S35F3_HUMAN
Putative thiamine transporter SLC35F3
Search

SLC35F3

0.96	Solute carrier family 35 member F3

0.53	GO:0015888	thiamine transport
0.44	GO:0055085	transmembrane transport

0.45

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|Q8IY51|TIGD4_HUMAN
Tigger transposable element-derived protein 4
Search

TIGD4

0.94	Tigger transposable element-derived protein 4

0.55	GO:0003677	DNA binding
0.33	GO:0003682	chromatin binding

0.37	GO:0005634	nucleus
0.33	GO:0000775	chromosome, centromeric region

sp|Q8IY57|YAF2_HUMAN
YY1-associated factor 2
Search

YAF2

0.95	YY1-associated factor 2 isoform B

0.70	GO:1903507	negative regulation of nucleic acid-templated transcription
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0030900	forebrain development
0.43	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.43	GO:0043066	negative regulation of apoptotic process
0.42	GO:0010629	negative regulation of gene expression
0.36	GO:0070317	negative regulation of G0 to G1 transition
0.34	GO:0006351	transcription, DNA-templated

0.80	GO:0003714	transcription corepressor activity
0.78	GO:0003713	transcription coactivator activity
0.48	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.43	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol

sp|Q8IY63|AMOL1_HUMAN
Angiomotin-like protein 1
Search

AMOTL1

0.83	Angiomotin like 1

0.87	GO:0003365	establishment of cell polarity involved in ameboidal cell migration
0.85	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.84	GO:0035329	hippo signaling
0.40	GO:0043534	blood vessel endothelial cell migration
0.39	GO:0034260	negative regulation of GTPase activity
0.39	GO:0001702	gastrulation with mouth forming second
0.39	GO:0040019	positive regulation of embryonic development
0.39	GO:0042074	cell migration involved in gastrulation
0.39	GO:0001570	vasculogenesis
0.39	GO:0016525	negative regulation of angiogenesis

0.72	GO:0042802	identical protein binding
0.40	GO:0043532	angiostatin binding
0.36	GO:0004872	receptor activity

0.82	GO:0030027	lamellipodium
0.81	GO:0005923	bicellular tight junction
0.80	GO:0016324	apical plasma membrane
0.80	GO:0008180	COP9 signalosome
0.72	GO:0031410	cytoplasmic vesicle
0.39	GO:0001726	ruffle
0.39	GO:0005884	actin filament
0.38	GO:0009897	external side of plasma membrane
0.32	GO:0097517	contractile actin filament bundle
0.32	GO:0042641	actomyosin

sp|Q8IY67|RAVR1_HUMAN
Ribonucleoprotein PTB-binding 1
Search

RAVER1

0.92	Ribonucleoprotein PTB-binding 1

0.46	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0022900	electron transport chain
0.33	GO:0035556	intracellular signal transduction

0.59	GO:0003723	RNA binding
0.36	GO:0004713	protein tyrosine kinase activity
0.35	GO:0051537	2 iron, 2 sulfur cluster binding
0.34	GO:0009055	electron transfer activity
0.34	GO:0005515	protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0019013	viral nucleocapsid
0.51	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.33	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.36

EC:2.7.10

GO:0004713

sp|Q8IY81|SPB1_HUMAN
pre-rRNA processing protein FTSJ3
Search

FTSJ3

0.97	pre-rRNA processing protein FTSJ3

0.73	GO:0000453	enzyme-directed rRNA 2'-O-methylation
0.49	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.69	GO:0008649	rRNA methyltransferase activity
0.46	GO:0008171	O-methyltransferase activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.77	GO:0030688	preribosome, small subunit precursor
0.69	GO:0005730	nucleolus
0.49	GO:0030687	preribosome, large subunit precursor

0.69

GO:0008649

sp|Q8IY82|DRC7_HUMAN
Dynein regulatory complex subunit 7
Search

DRC7

0.93	Dynein regulatory complex subunit 7

0.30

GO:0005488

binding

0.49	GO:0005737	cytoplasm
0.42	GO:0031514	motile cilium
0.40	GO:0005856	cytoskeleton

sp|Q8IY84|NIM1_HUMAN
Serine/threonine-protein kinase NIM1
Search

NIM1K

0.97	Serine/threonine-protein kinase NIM1

0.63	GO:0006468	protein phosphorylation
0.42	GO:0035556	intracellular signal transduction
0.33	GO:0007229	integrin-mediated signaling pathway

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0000287	magnesium ion binding
0.33	GO:0005509	calcium ion binding

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004674

sp|Q8IY85|EFC13_HUMAN
EF-hand calcium-binding domain-containing protein 13
Search

EFCAB13

0.97	EF-hand calcium-binding domain-containing protein 13

0.70

GO:0005509

calcium ion binding

sp|Q8IY92|SLX4_HUMAN
Structure-specific endonuclease subunit SLX4
Search

SLX4

0.61	LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4

0.73	GO:1904431	positive regulation of t-circle formation
0.73	GO:0001325	formation of extrachromosomal circular DNA
0.73	GO:0090737	telomere maintenance via telomere trimming
0.72	GO:0061820	telomeric D-loop disassembly
0.72	GO:0072429	response to intra-S DNA damage checkpoint signaling
0.71	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing
0.69	GO:1904357	negative regulation of telomere maintenance via telomere lengthening
0.63	GO:0006260	DNA replication
0.62	GO:0000724	double-strand break repair via homologous recombination
0.59	GO:0043085	positive regulation of catalytic activity

0.77	GO:0017108	5'-flap endonuclease activity
0.75	GO:0048257	3'-flap endonuclease activity
0.65	GO:0008821	crossover junction endodeoxyribonuclease activity
0.60	GO:0008047	enzyme activator activity
0.38	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.80	GO:0033557	Slx1-Slx4 complex
0.72	GO:0070522	ERCC4-ERCC1 complex
0.65	GO:0000784	nuclear chromosome, telomeric region
0.63	GO:0048476	Holliday junction resolvase complex
0.61	GO:0000790	nuclear chromatin
0.60	GO:0030054	cell junction
0.57	GO:0005654	nucleoplasm
0.56	GO:0005829	cytosol

0.65

EC:3.1.22.4

GO:0008821

sp|Q8IY95|TM192_HUMAN
Transmembrane protein 192
Search

TMEM192

0.80	Transmembrane protein 192

0.54

GO:0042803

protein homodimerization activity

0.59	GO:0005765	lysosomal membrane
0.58	GO:0005770	late endosome
0.57	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005654	nucleoplasm
0.38	GO:0070062	extracellular exosome
0.37	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q8IYA2|C144C_HUMAN
Putative coiled-coil domain-containing protein 144C
Search

0.12	Putative coiled-coil domain-containing protein 144C

0.62	GO:0045599	negative regulation of fat cell differentiation
0.56	GO:0040015	negative regulation of multicellular organism growth
0.56	GO:0060259	regulation of feeding behavior
0.55	GO:0046621	negative regulation of organ growth
0.55	GO:0046627	negative regulation of insulin receptor signaling pathway
0.54	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:0019217	regulation of fatty acid metabolic process
0.52	GO:0042593	glucose homeostasis
0.37	GO:0007018	microtubule-based movement
0.35	GO:0007062	sister chromatid cohesion

0.47	GO:0005515	protein binding
0.40	GO:0044877	macromolecular complex binding
0.37	GO:0003777	microtubule motor activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003677	DNA binding

0.70	GO:0005813	centrosome
0.53	GO:0005884	actin filament
0.41	GO:0005829	cytosol
0.38	GO:0016459	myosin complex
0.34	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|Q8IYA6|CKP2L_HUMAN
Cytoskeleton-associated protein 2-like
Search

CKAP2L

0.68	Cytoskeleton associated protein 2 like

0.42	GO:0001660	fever generation
0.41	GO:0051781	positive regulation of cell division
0.39	GO:0010469	regulation of receptor activity
0.39	GO:0006955	immune response
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter
0.34	GO:0016570	histone modification

0.42	GO:0005149	interleukin-1 receptor binding
0.40	GO:0005125	cytokine activity

0.80	GO:0072686	mitotic spindle
0.77	GO:0005813	centrosome
0.68	GO:0005829	cytosol
0.48	GO:0000922	spindle pole
0.39	GO:0005615	extracellular space
0.34	GO:0016593	Cdc73/Paf1 complex

sp|Q8IYA7|MKX_HUMAN
Homeobox protein Mohawk
Search

MKX

0.97	Homeobox protein mohawk A

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.42	GO:0061061	muscle structure development
0.40	GO:0048513	animal organ development
0.40	GO:1904888	cranial skeletal system development
0.40	GO:0048706	embryonic skeletal system development
0.39	GO:0030154	cell differentiation
0.39	GO:0009653	anatomical structure morphogenesis
0.39	GO:1902679	negative regulation of RNA biosynthetic process

0.61	GO:0043565	sequence-specific DNA binding
0.37	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0001085	RNA polymerase II transcription factor binding
0.37	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding

0.59	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex

sp|Q8IYA8|IHO1_HUMAN
Interactor of HORMAD1 protein 1
Search

CCDC36

0.96	Coiled-coil domain-containing protein 36

0.85	GO:0042138	meiotic DNA double-strand break formation
0.75	GO:0060629	regulation of homologous chromosome segregation
0.69	GO:0007129	synapsis
0.67	GO:0048477	oogenesis
0.66	GO:0007283	spermatogenesis
0.65	GO:0006310	DNA recombination

0.65

GO:0000794

condensed nuclear chromosome

sp|Q8IYB0|YK038_HUMAN
Putative uncharacterized protein MGC39545
Search

sp|Q8IYB1|M21D2_HUMAN
Protein MB21D2
Search

MB21D2

0.95	Mab-21 domain containing 2

0.81	GO:0045296	cadherin binding
0.74	GO:0032403	protein complex binding

0.30

GO:0031224

intrinsic component of membrane

sp|Q8IYB3|SRRM1_HUMAN
Serine/arginine repetitive matrix protein 1
Search

SRRM1

0.76	Serine and arginine repetitive matrix 1

0.68	GO:0006397	mRNA processing
0.38	GO:0008380	RNA splicing
0.36	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0031123	RNA 3'-end processing
0.35	GO:0051028	mRNA transport
0.35	GO:0006405	RNA export from nucleus

0.36	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.54	GO:0016607	nuclear speck
0.52	GO:0071013	catalytic step 2 spliceosome
0.39	GO:0016363	nuclear matrix
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q8IYB4|PEX5R_HUMAN
PEX5-related protein
Search

PEX5L

0.97	Peroxisomal biogenesis factor 5 like

0.66	GO:0016560	protein import into peroxisome matrix, docking
0.49	GO:0043949	regulation of cAMP-mediated signaling
0.43	GO:0045185	maintenance of protein location
0.42	GO:0042391	regulation of membrane potential
0.42	GO:0051461	positive regulation of corticotropin secretion
0.40	GO:0045055	regulated exocytosis
0.36	GO:0098655	cation transmembrane transport

0.86	GO:0000268	peroxisome targeting sequence binding
0.71	GO:0031267	small GTPase binding
0.41	GO:0005221	intracellular cyclic nucleotide activated cation channel activity

0.74	GO:0043235	receptor complex
0.63	GO:0031903	microbody membrane
0.62	GO:0044439	peroxisomal part
0.56	GO:0005829	cytosol
0.43	GO:0030425	dendrite
0.42	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.40	GO:0051286	cell tip
0.39	GO:0048471	perinuclear region of cytoplasm

sp|Q8IYB5|SMAP1_HUMAN
Stromal membrane-associated protein 1
Search

SMAP1

0.96	Small ArfGAP 1

0.76	GO:0043547	positive regulation of GTPase activity
0.75	GO:2000369	regulation of clathrin-dependent endocytosis
0.74	GO:0045648	positive regulation of erythrocyte differentiation
0.36	GO:0031532	actin cytoskeleton reorganization

0.76	GO:0005096	GTPase activator activity
0.68	GO:0030276	clathrin binding
0.53	GO:0046872	metal ion binding

0.44

GO:0005737

cytoplasm

sp|Q8IYB7|DI3L2_HUMAN
DIS3-like exonuclease 2
Search

DIS3L2

0.93	DIS3 like 3'-5' exoribonuclease 2

0.81	GO:0010587	miRNA catabolic process
0.68	GO:0051306	mitotic sister chromatid separation
0.68	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.64	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic
0.63	GO:0019827	stem cell population maintenance
0.61	GO:0008285	negative regulation of cell proliferation
0.56	GO:0006364	rRNA processing
0.54	GO:0048793	pronephros development
0.50	GO:0006914	autophagy

0.72	GO:0000175	3'-5'-exoribonuclease activity
0.65	GO:0008266	poly(U) RNA binding
0.51	GO:0000287	magnesium ion binding

0.72	GO:0000932	P-body
0.64	GO:0000178	exosome (RNase complex)

0.72

EC:3.1.13

GO:0000175

sp|Q8IYB8|SUV3_HUMAN
ATP-dependent RNA helicase SUPV3L1, mitochondrial
Search

SUPV3L1

0.90	ATP-dependent RNA helicase DDX55

0.62	GO:0035945	mitochondrial ncRNA surveillance
0.62	GO:0035946	mitochondrial mRNA surveillance
0.61	GO:0000965	mitochondrial RNA 3'-end processing
0.61	GO:0000962	positive regulation of mitochondrial RNA catabolic process
0.61	GO:0000958	mitochondrial mRNA catabolic process
0.59	GO:0070827	chromatin maintenance
0.58	GO:0070584	mitochondrion morphogenesis
0.56	GO:0030307	positive regulation of cell growth
0.53	GO:0043066	negative regulation of apoptotic process
0.49	GO:0032392	DNA geometric change

0.58	GO:0016817	hydrolase activity, acting on acid anhydrides
0.53	GO:0003725	double-stranded RNA binding
0.51	GO:0042803	protein homodimerization activity
0.46	GO:0140098	catalytic activity, acting on RNA
0.46	GO:0140097	catalytic activity, acting on DNA
0.42	GO:0003677	DNA binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0045025	mitochondrial degradosome
0.56	GO:0042645	mitochondrial nucleoid
0.45	GO:0005634	nucleus

0.58

EC:3.6

GO:0016817

sp|Q8IYB9|ZN595_HUMAN
Zinc finger protein 595
Search

0.75	Zinc finger protein 732

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0097659	nucleic acid-templated transcription
0.39	GO:0010467	gene expression
0.39	GO:0034645	cellular macromolecule biosynthetic process

0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle

sp|Q8IYD1|ERF3B_HUMAN
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B
Search

GSPT1

0.91	G1 to S phase transition 2

0.55	GO:0006415	translational termination
0.52	GO:0008213	protein alkylation
0.49	GO:0043414	macromolecule methylation
0.48	GO:0002181	cytoplasmic translation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.55	GO:0008079	translation termination factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0018444	translation release factor complex
0.44	GO:0005829	cytosol

sp|Q8IYD2|KLD8A_HUMAN
Kelch domain-containing protein 8A
Search

KLHDC8A

0.97	Kelch domain-containing protein 8A

0.65	GO:0016567	protein ubiquitination
0.41	GO:0051301	cell division
0.41	GO:0007049	cell cycle
0.36	GO:0006468	protein phosphorylation

0.66	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0031463	Cul3-RING ubiquitin ligase complex
0.54	GO:0005829	cytosol
0.46	GO:0030496	midbody
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004842

sp|Q8IYD8|FANCM_HUMAN
Fanconi anemia group M protein
Search

FANCM

0.84	Fanconi anemia complementation group M

0.67	GO:0000712	resolution of meiotic recombination intermediates
0.65	GO:0031297	replication fork processing
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.39	GO:0036297	interstrand cross-link repair

0.63	GO:0004518	nuclease activity
0.60	GO:0003682	chromatin binding
0.55	GO:0003677	DNA binding
0.52	GO:0030554	adenyl nucleotide binding
0.51	GO:0032555	purine ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004386	helicase activity
0.36	GO:0005515	protein binding

0.67	GO:0071821	FANCM-MHF complex
0.66	GO:0043240	Fanconi anaemia nuclear complex
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:3.1

GO:0004518

sp|Q8IYD9|LAS2_HUMAN
Lung adenoma susceptibility protein 2
Search

0.86	Lung adenoma susceptibility protein 2

0.68

GO:0008285

negative regulation of cell proliferation

0.53	GO:0005515	protein binding
0.36	GO:0003676	nucleic acid binding

0.56

GO:0005576

extracellular region

sp|Q8IYE0|CC146_HUMAN
Coiled-coil domain-containing protein 146
Search

CCDC146

0.97	Coiled-coil domain-containing protein 146

0.38

GO:0005515

protein binding

0.82

GO:0005814

centriole

sp|Q8IYE1|CCD13_HUMAN
Coiled-coil domain-containing protein 13
Search

CCDC13

0.95	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 13

0.84	GO:1905515	non-motile cilium assembly
0.83	GO:0031122	cytoplasmic microtubule organization
0.64	GO:0006974	cellular response to DNA damage stimulus
0.33	GO:0000413	protein peptidyl-prolyl isomerization
0.32	GO:0006457	protein folding
0.32	GO:0006886	intracellular protein transport
0.32	GO:0061025	membrane fusion
0.32	GO:0016192	vesicle-mediated transport

0.37	GO:0005515	protein binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.85	GO:0034451	centriolar satellite
0.68	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.41	GO:0042995	cell projection
0.30	GO:0016020	membrane

0.33

EC:5.2.1.8

GO:0003755

sp|Q8IYF1|ELOA2_HUMAN
Elongin-A2
Search

ELOA

0.68	Transcription elongation factor B polypeptide 3

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0006414	translational elongation
0.48	GO:0006368	transcription elongation from RNA polymerase II promoter
0.42	GO:0032784	regulation of DNA-templated transcription, elongation
0.37	GO:0055114	oxidation-reduction process
0.32	GO:0006508	proteolysis

0.50	GO:0003746	translation elongation factor activity
0.39	GO:0005515	protein binding
0.37	GO:0016491	oxidoreductase activity
0.37	GO:0003735	structural constituent of ribosome
0.32	GO:0008233	peptidase activity

0.85	GO:0070449	elongin complex
0.37	GO:0005840	ribosome

0.37

GO:0016491

sp|Q8IYF3|TEX11_HUMAN
Testis-expressed protein 11
Search

TEX11

0.97	Testis-expressed protein 11

0.78	GO:0051321	meiotic cell cycle
0.56	GO:0035822	gene conversion
0.55	GO:0070193	synaptonemal complex organization
0.54	GO:0008584	male gonad development
0.53	GO:0009566	fertilization
0.53	GO:0035825	homologous recombination
0.52	GO:0048232	male gamete generation
0.52	GO:0051304	chromosome separation
0.52	GO:0022412	cellular process involved in reproduction in multicellular organism
0.51	GO:0043066	negative regulation of apoptotic process

0.36	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.57	GO:0000801	central element
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IYG6|LRC56_HUMAN
Leucine-rich repeat-containing protein 56
Search

LRRC56

0.94	LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 56

0.59	GO:0070507	regulation of microtubule cytoskeleton organization
0.48	GO:0007165	signal transduction

sp|Q8IYH5|ZZZ3_HUMAN
ZZ-type zinc finger-containing protein 3
Search

ZZZ3

0.97	ZZ-type zinc finger-containing protein 3

0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.62	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.55	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.50	GO:0005730	nucleolus

sp|Q8IYI0|CT196_HUMAN
Uncharacterized protein C20orf196
Search

sp|Q8IYI6|EXOC8_HUMAN
Exocyst complex component 8
Search

EXOC8

0.96	Exocyst complex component 8

0.76	GO:0006887	exocytosis
0.61	GO:0022617	extracellular matrix disassembly
0.59	GO:0007032	endosome organization
0.52	GO:0051601	exocyst localization
0.49	GO:0048278	vesicle docking
0.45	GO:0043623	cellular protein complex assembly
0.39	GO:0015031	protein transport
0.36	GO:0016241	regulation of macroautophagy
0.32	GO:0055114	oxidation-reduction process

0.61	GO:0017160	Ral GTPase binding
0.35	GO:0035091	phosphatidylinositol binding
0.35	GO:0031418	L-ascorbic acid binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0005506	iron ion binding

0.78	GO:0000145	exocyst
0.56	GO:0005770	late endosome
0.50	GO:0005829	cytosol
0.44	GO:0030426	growth cone
0.42	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0031252	cell leading edge
0.36	GO:0097546	ciliary base
0.36	GO:0097731	9+0 non-motile cilium
0.34	GO:0005886	plasma membrane

0.34

GO:0016705

sp|Q8IYI8|ZN440_HUMAN
Zinc finger protein 440
Search

0.87	Zinc finger protein 440

0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression
0.41	GO:0097659	nucleic acid-templated transcription
0.40	GO:0010467	gene expression
0.39	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0005515	protein binding
0.36	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle

sp|Q8IYJ0|PIANP_HUMAN
PILR alpha-associated neural protein
Search

PIANP

0.97	PILR alpha-associated neural protein isoform a

0.36

GO:0050776

regulation of immune response

0.45	GO:0016323	basolateral plasma membrane
0.44	GO:0005912	adherens junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IYJ1|CPNE9_HUMAN
Copine-9
Search

CPNE9

0.81	Copine VIII

0.85	GO:1903861	positive regulation of dendrite extension
0.37	GO:0035335	peptidyl-tyrosine dephosphorylation

0.37	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0003676	nucleic acid binding

0.55	GO:0043025	neuronal cell body
0.53	GO:0043005	neuron projection
0.45	GO:0070062	extracellular exosome

0.37

EC:3.1.3.48

GO:0004725

sp|Q8IYJ2|CJ067_HUMAN
Uncharacterized protein C10orf67, mitochondrial
Search

sp|Q8IYJ3|SYTL1_HUMAN
Synaptotagmin-like protein 1
Search

SYTL1

0.97	Synaptotagmin like 1

0.77	GO:0006887	exocytosis
0.64	GO:0006886	intracellular protein transport
0.52	GO:0017158	regulation of calcium ion-dependent exocytosis
0.51	GO:0048489	synaptic vesicle transport
0.51	GO:0099504	synaptic vesicle cycle
0.51	GO:0006906	vesicle fusion
0.50	GO:0099643	signal release from synapse
0.50	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.48	GO:0006836	neurotransmitter transport
0.47	GO:0001505	regulation of neurotransmitter levels

0.78	GO:0017137	Rab GTPase binding
0.51	GO:0019905	syntaxin binding
0.50	GO:0005544	calcium-dependent phospholipid binding
0.50	GO:0030276	clathrin binding
0.46	GO:0005509	calcium ion binding
0.45	GO:0042043	neurexin family protein binding
0.36	GO:0001786	phosphatidylserine binding
0.35	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0019902	phosphatase binding

0.50	GO:0070382	exocytic vesicle
0.48	GO:0098793	presynapse
0.46	GO:0005886	plasma membrane
0.45	GO:0042470	melanosome
0.42	GO:0019898	extrinsic component of membrane
0.40	GO:0070062	extracellular exosome
0.37	GO:0005902	microvillus
0.36	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

sp|Q8IYK2|CC105_HUMAN
Coiled-coil domain-containing protein 105
Search

CCDC105

0.97	Coiled-coil domain-containing protein 105

0.49

GO:0006508

proteolysis

0.59

GO:0004197

cysteine-type endopeptidase activity

0.63

GO:0070062

extracellular exosome

0.59

EC:3.4.22

GO:0004197

sp|Q8IYK4|GT252_HUMAN
Procollagen galactosyltransferase 2
Search

COLGALT2

0.96	Procollagen galactosyltransferase 2

0.47	GO:1904028	positive regulation of collagen fibril organization
0.33	GO:0006412	translation

0.59	GO:0016757	transferase activity, transferring glycosyl groups
0.39	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0005515	protein binding
0.34	GO:0003735	structural constituent of ribosome

0.46	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.59

GO:0016757

sp|Q8IYK8|REM2_HUMAN
GTP-binding protein REM 2
Search

REM2

0.92	GTP-binding protein RAD

0.79	GO:1901841	regulation of high voltage-gated calcium channel activity
0.73	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.61	GO:0007165	signal transduction
0.35	GO:0071542	dopaminergic neuron differentiation
0.34	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0030308	negative regulation of cell growth
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005246	calcium channel regulator activity
0.36	GO:0005516	calmodulin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003700	DNA binding transcription factor activity

0.36	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q8IYL2|TRM44_HUMAN
Probable tRNA (uracil-O(2)-)-methyltransferase
Search

TRMT44

0.91	Methyltransferase like 19

0.63	GO:0032259	methylation
0.44	GO:0006400	tRNA modification
0.37	GO:0044260	cellular macromolecule metabolic process

0.63	GO:0008168	methyltransferase activity
0.52	GO:0046872	metal ion binding
0.43	GO:0140101	catalytic activity, acting on a tRNA

0.34

GO:0005737

cytoplasm

0.63

GO:0008168

sp|Q8IYL3|CA174_HUMAN
UPF0688 protein C1orf174
Search

sp|Q8IYL9|PSYR_HUMAN
Psychosine receptor
Search

GPR65

0.97	Psychosine receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0010447	response to acidic pH
0.59	GO:0051496	positive regulation of stress fiber assembly
0.58	GO:0090630	activation of GTPase activity
0.58	GO:0019933	cAMP-mediated signaling
0.54	GO:0031532	actin cytoskeleton reorganization
0.52	GO:0035025	positive regulation of Rho protein signal transduction
0.50	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.46	GO:0072144	glomerular mesangial cell development
0.45	GO:0060055	angiogenesis involved in wound healing

0.72	GO:0004930	G-protein coupled receptor activity
0.36	GO:0001614	purinergic nucleotide receptor activity
0.34	GO:0001653	peptide receptor activity
0.34	GO:0030594	neurotransmitter receptor activity

0.44	GO:0005887	integral component of plasma membrane
0.38	GO:0005622	intracellular

sp|Q8IYM0|F186B_HUMAN
Protein FAM186B
Search

sp|Q8IYM1|SEP12_HUMAN
Septin-12
Search

SEPT12

0.92	neuronal-specific septin-3-like isoform X2

0.54	GO:0007049	cell cycle
0.53	GO:0097722	sperm motility
0.38	GO:0007283	spermatogenesis
0.37	GO:0051301	cell division
0.36	GO:0030154	cell differentiation
0.33	GO:0002098	tRNA wobble uridine modification

0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.47	GO:0046983	protein dimerization activity
0.36	GO:0035091	phosphatidylinositol binding

0.58	GO:0097227	sperm annulus
0.56	GO:0031105	septin complex
0.54	GO:0030496	midbody
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005819	spindle
0.37	GO:0097517	contractile actin filament bundle
0.37	GO:0032154	cleavage furrow
0.37	GO:0042641	actomyosin
0.34	GO:0033588	Elongator holoenzyme complex
0.33	GO:0045202	synapse

sp|Q8IYM2|SLN12_HUMAN
Schlafen family member 12
Search

0.89	Schlafen family member 12 like

0.52	GO:0036345	platelet maturation
0.49	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.46	GO:0016075	rRNA catabolic process
0.46	GO:0051607	defense response to virus
0.45	GO:0006402	mRNA catabolic process
0.44	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0071287	cellular response to manganese ion
0.38	GO:0071286	cellular response to magnesium ion
0.38	GO:0008285	negative regulation of cell proliferation
0.35	GO:0050868	negative regulation of T cell activation

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0043022	ribosome binding
0.44	GO:0004521	endoribonuclease activity
0.43	GO:0000049	tRNA binding
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.50	GO:0005634	nucleus
0.40	GO:0016235	aggresome
0.37	GO:0005737	cytoplasm
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q8IYM9|TRI22_HUMAN
E3 ubiquitin-protein ligase TRIM22
Search

0.92	tripartite motif-containing protein 6

0.56	GO:0009615	response to virus
0.56	GO:0045087	innate immune response
0.55	GO:0002252	immune effector process
0.54	GO:0006914	autophagy
0.54	GO:0016567	protein ubiquitination
0.54	GO:0098542	defense response to other organism
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.52	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.52	GO:0070206	protein trimerization
0.49	GO:0031325	positive regulation of cellular metabolic process

0.62	GO:0008270	zinc ion binding
0.54	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0030674	protein binding, bridging
0.50	GO:0019901	protein kinase binding
0.43	GO:0038187	pattern recognition receptor activity
0.40	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0016874	ligase activity
0.38	GO:0038023	signaling receptor activity
0.38	GO:0008134	transcription factor binding
0.35	GO:0003714	transcription corepressor activity

0.46	GO:0016604	nuclear body
0.44	GO:0005794	Golgi apparatus
0.42	GO:0000932	P-body
0.39	GO:0005829	cytosol
0.35	GO:1990462	omegasome

0.39	EC:6	GO:0016874
0.54	KEGG:R03876	GO:0004842

sp|Q8IYN0|ZN100_HUMAN
Zinc finger protein 100
Search

0.85	Zinc finger protein 680

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0097659	nucleic acid-templated transcription
0.41	GO:0010467	gene expression
0.40	GO:0034645	cellular macromolecule biosynthetic process

0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.42	GO:0043227	membrane-bounded organelle

sp|Q8IYN2|TCAL8_HUMAN
Transcription elongation factor A protein-like 8
Search

TCEAL8

0.97	Transcription elongation factor A like 8

0.65	GO:0006414	translational elongation
0.55	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0097659	nucleic acid-templated transcription

0.66	GO:0050699	WW domain binding
0.66	GO:0003746	translation elongation factor activity

0.49

GO:0005634

nucleus

sp|Q8IYN6|UBAD2_HUMAN
UBA-like domain-containing protein 2
Search

UBALD2

0.96	UBA like domain containing 2

0.43	GO:0030097	hemopoiesis
0.43	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.43	GO:0018108	peptidyl-tyrosine phosphorylation
0.41	GO:0030154	cell differentiation

0.43	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.43

EC:2.7.10.1

GO:0004714

sp|Q8IYP2|PRS58_HUMAN
Serine protease 58
Search

PRSS58

0.94	cationic trypsin-3

0.61	GO:0006508	proteolysis
0.44	GO:2000344	positive regulation of acrosome reaction
0.43	GO:0007339	binding of sperm to zona pellucida
0.43	GO:0070613	regulation of protein processing
0.41	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.41	GO:0070997	neuron death
0.41	GO:0016477	cell migration
0.40	GO:0051604	protein maturation
0.39	GO:0032501	multicellular organismal process
0.39	GO:0042060	wound healing

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005509	calcium ion binding
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0097655	serpin family protein binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0008083	growth factor activity
0.32	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H

0.45	GO:0005576	extracellular region
0.44	GO:0030141	secretory granule
0.43	GO:0097223	sperm part
0.38	GO:0005794	Golgi apparatus
0.34	GO:0097180	serine protease inhibitor complex
0.34	GO:0045177	apical part of cell
0.33	GO:0005634	nucleus
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0043233	organelle lumen
0.32	GO:0005739	mitochondrion

0.69

GO:0004252

sp|Q8IYP9|ZDH23_HUMAN
Palmitoyltransferase ZDHHC23
Search

ZDHHC23

0.55	Palmitoyltransferase

0.58	GO:0018345	protein palmitoylation
0.57	GO:0072659	protein localization to plasma membrane

0.79

GO:0019706

protein-cysteine S-palmitoyltransferase activity

0.30

GO:0031224

intrinsic component of membrane

0.79

GO:0019706

sp|Q8IYQ7|THNS1_HUMAN
Threonine synthase-like 1
Search

THNSL1

0.97	Threonine synthase like 1

0.59

GO:0006520

cellular amino acid metabolic process

0.65	GO:0030170	pyridoxal phosphate binding
0.38	GO:0004795	threonine synthase activity

0.30

GO:0031224

intrinsic component of membrane

0.38

EC:4.2.3.1

GO:0004795

sp|Q8IYR0|CF206_HUMAN
Cilia- and flagella-associated protein 206
Search

CFAP206

0.80	CMP-sialic acid transporter

0.65	GO:0035082	axoneme assembly
0.65	GO:0003341	cilium movement
0.36	GO:0009132	nucleoside diphosphate metabolic process
0.35	GO:0006518	peptide metabolic process
0.35	GO:0043604	amide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:1901566	organonitrogen compound biosynthetic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.40	GO:0005515	protein binding
0.36	GO:0030145	manganese ion binding
0.35	GO:0000287	magnesium ion binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

0.79	GO:0031514	motile cilium
0.74	GO:0097649	A axonemal microtubule
0.73	GO:0001534	radial spoke
0.35	GO:0005840	ribosome

0.34

EC:3.6.1

GO:0016818

sp|Q8IYR2|SMYD4_HUMAN
SET and MYND domain-containing protein 4
Search

SMYD4

0.88	SET and MYND domain-containing protein 4

0.61	GO:0032259	methylation
0.39	GO:0042051	compound eye photoreceptor development
0.33	GO:0055114	oxidation-reduction process

0.62	GO:0008168	methyltransferase activity
0.53	GO:0046872	metal ion binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.62

GO:0008168

sp|Q8IYR6|TEFF1_HUMAN
Tomoregulin-1
Search

0.97	Transmembrane protein with EGF like and two follistatin like domains 1

0.41	GO:0045720	negative regulation of integrin biosynthetic process
0.40	GO:0051497	negative regulation of stress fiber assembly
0.40	GO:0090505	epiboly involved in wound healing
0.39	GO:0030336	negative regulation of cell migration
0.38	GO:0016477	cell migration
0.37	GO:0007275	multicellular organism development
0.33	GO:0035023	regulation of Rho protein signal transduction

0.32

GO:0003723

RNA binding

0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IYS0|GRM1C_HUMAN
GRAM domain-containing protein 1C
Search

GRAMD1C

0.97	GRAM domain-containing protein 1C

0.34

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q8IYS1|P20D2_HUMAN
Peptidase M20 domain-containing protein 2
Search

PM20D2

0.95	Peptidase M20 domain-containing protein 2

0.55	GO:0032268	regulation of cellular protein metabolic process
0.50	GO:0006508	proteolysis
0.35	GO:0001522	pseudouridine synthesis
0.34	GO:0042254	ribosome biogenesis

0.61	GO:0016805	dipeptidase activity
0.36	GO:0030515	snoRNA binding

0.56	GO:0005654	nucleoplasm
0.39	GO:0070062	extracellular exosome

0.61

EC:3.4.13

GO:0016805

sp|Q8IYS2|K2013_HUMAN
Uncharacterized protein KIAA2013
Search

0.35	GO:0009190	cyclic nucleotide biosynthetic process
0.34	GO:0046068	cGMP metabolic process
0.34	GO:0035556	intracellular signal transduction
0.33	GO:0009152	purine ribonucleotide biosynthetic process

0.35	GO:0016849	phosphorus-oxygen lyase activity
0.34	GO:0009975	cyclase activity
0.33	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:4.6

GO:0016849

sp|Q8IYS4|CP071_HUMAN
Uncharacterized protein C16orf71
Search

sp|Q8IYS5|OSCAR_HUMAN
Osteoclast-associated immunoglobulin-like receptor
Search

OSCAR

0.97	Osteoclast-associated receptor isoform 3 (Predicted)

0.59	GO:0043312	neutrophil degranulation
0.50	GO:0050776	regulation of immune response

0.61	GO:1904724	tertiary granule lumen
0.61	GO:0035580	specific granule lumen
0.61	GO:0070062	extracellular exosome
0.46	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q8IYS8|BD1L2_HUMAN
Biorientation of chromosomes in cell division protein 1-like 2
Search

0.63	GO:0051301	cell division
0.51	GO:0071962	mitotic sister chromatid cohesion, centromeric
0.51	GO:1990758	mitotic sister chromatid biorientation
0.49	GO:0071459	protein localization to chromosome, centromeric region
0.48	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.48	GO:0031297	replication fork processing
0.41	GO:0006974	cellular response to DNA damage stimulus
0.36	GO:0010469	regulation of receptor activity

0.50	GO:0051721	protein phosphatase 2A binding
0.48	GO:0004864	protein phosphatase inhibitor activity
0.37	GO:0005179	hormone activity
0.33	GO:0003677	DNA binding

0.50	GO:0000777	condensed chromosome kinetochore
0.48	GO:0005815	microtubule organizing center
0.48	GO:0005876	spindle microtubule
0.47	GO:0000922	spindle pole
0.43	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.35	GO:0005576	extracellular region

sp|Q8IYT1|FA71A_HUMAN
Protein FAM71A
Search

sp|Q8IYT2|CMTR2_HUMAN
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2
Search

CMTR2

0.97	FtsJ methyltransferase domain-containing protein 1

0.64	GO:0097310	cap2 mRNA methylation
0.53	GO:0006370	7-methylguanosine mRNA capping
0.36	GO:0007424	open tracheal system development
0.33	GO:0035239	tube morphogenesis
0.32	GO:0016477	cell migration
0.31	GO:0055114	oxidation-reduction process

0.63	GO:0008168	methyltransferase activity
0.46	GO:0140098	catalytic activity, acting on RNA
0.32	GO:0016491	oxidoreductase activity

0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.32	GO:0012505	endomembrane system
0.32	GO:0031967	organelle envelope
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.63

GO:0008168

sp|Q8IYT3|CC170_HUMAN
Coiled-coil domain-containing protein 170
Search

CCDC170

0.97	Coiled-coil domain-containing protein 170

0.50

GO:0005515

protein binding

sp|Q8IYT4|KATL2_HUMAN
Katanin p60 ATPase-containing subunit A-like 2
Search

KATNAL2

0.93	Katanin p60 ATPase-containing subunit A-like 2

0.78

GO:0051013

microtubule severing

0.79	GO:0008568	microtubule-severing ATPase activity
0.68	GO:0008017	microtubule binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0000922	spindle pole
0.68	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.6.4.3

GO:0008568

sp|Q8IYT8|ULK2_HUMAN
Serine/threonine-protein kinase ULK2
Search

ULK2

0.91	Unc-51 like autophagy activating kinase 2

0.71	GO:0075044	autophagy of host cells involved in interaction with symbiont
0.67	GO:0048667	cell morphogenesis involved in neuron differentiation
0.67	GO:0048812	neuron projection morphogenesis
0.64	GO:0046777	protein autophosphorylation
0.64	GO:0048588	developmental cell growth
0.63	GO:0061564	axon development
0.63	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.63	GO:0010975	regulation of neuron projection development
0.63	GO:0060560	developmental growth involved in morphogenesis
0.59	GO:0061387	regulation of extent of cell growth

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.66	GO:0034045	phagophore assembly site membrane
0.36	GO:0097635	extrinsic component of autophagosome membrane
0.36	GO:0097629	extrinsic component of omegasome membrane
0.35	GO:0032045	guanyl-nucleotide exchange factor complex
0.35	GO:1990316	Atg1/ULK1 kinase complex
0.34	GO:0005829	cytosol

0.70

GO:0004674

sp|Q8IYU2|HACE1_HUMAN
E3 ubiquitin-protein ligase HACE1
Search

HACE1

0.93	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

0.72	GO:0016567	protein ubiquitination
0.64	GO:0007030	Golgi organization
0.61	GO:0030334	regulation of cell migration
0.60	GO:0006511	ubiquitin-dependent protein catabolic process
0.55	GO:0061025	membrane fusion

0.73	GO:0004842	ubiquitin-protein transferase activity
0.66	GO:0048365	Rac GTPase binding
0.63	GO:0017137	Rab GTPase binding
0.50	GO:0061659	ubiquitin-like protein ligase activity
0.49	GO:0016874	ligase activity

0.61	GO:0016604	nuclear body
0.58	GO:0000139	Golgi membrane
0.56	GO:0005783	endoplasmic reticulum

0.49	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q8IYU4|UBQLN_HUMAN
Ubiquilin-like protein
Search

UBQLNL

0.97	Ubiquilin like

0.79	GO:1901340	negative regulation of store-operated calcium channel activity
0.78	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process
0.76	GO:0035973	aggrephagy
0.75	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway
0.72	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.72	GO:0097352	autophagosome maturation
0.70	GO:0030433	ubiquitin-dependent ERAD pathway
0.70	GO:0071456	cellular response to hypoxia
0.68	GO:0000045	autophagosome assembly
0.68	GO:0031398	positive regulation of protein ubiquitination

0.71	GO:0031593	polyubiquitin modification-dependent protein binding
0.65	GO:0019900	kinase binding
0.62	GO:0042802	identical protein binding
0.50	GO:0004984	olfactory receptor activity
0.49	GO:0004930	G-protein coupled receptor activity
0.39	GO:0019215	intermediate filament binding
0.37	GO:0019904	protein domain specific binding
0.37	GO:0005102	receptor binding
0.36	GO:0016746	transferase activity, transferring acyl groups

0.72	GO:0016235	aggresome
0.70	GO:0005776	autophagosome
0.66	GO:0048471	perinuclear region of cytoplasm
0.60	GO:0005783	endoplasmic reticulum
0.59	GO:0005829	cytosol
0.58	GO:0005654	nucleoplasm
0.53	GO:0005886	plasma membrane
0.52	GO:0043234	protein complex
0.43	GO:1905369	endopeptidase complex
0.43	GO:0031410	cytoplasmic vesicle

0.36

GO:0016746

sp|Q8IYU8|MICU2_HUMAN
Calcium uptake protein 2, mitochondrial
Search

MICU2

0.95	Mitochondrial calcium uptake 2

0.63	GO:0051562	negative regulation of mitochondrial calcium ion concentration
0.61	GO:0006851	mitochondrial calcium ion transmembrane transport
0.59	GO:0051561	positive regulation of mitochondrial calcium ion concentration
0.59	GO:0070509	calcium ion import
0.58	GO:0060401	cytosolic calcium ion transport
0.33	GO:0007059	chromosome segregation
0.33	GO:0007229	integrin-mediated signaling pathway
0.33	GO:0010469	regulation of receptor activity

0.69	GO:0005509	calcium ion binding
0.53	GO:0046982	protein heterodimerization activity
0.34	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0008083	growth factor activity

0.60	GO:1990246	uniplex complex
0.56	GO:0005758	mitochondrial intermembrane space
0.33	GO:0000940	condensed chromosome outer kinetochore

0.34

GO:0019706

sp|Q8IYV9|IZUM1_HUMAN
Izumo sperm-egg fusion protein 1
Search

IZUMO1

0.97	Izumo sperm-egg fusion protein 1

0.85	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.85	GO:0035036	sperm-egg recognition
0.46	GO:0034113	heterotypic cell-cell adhesion

0.73	GO:0005102	receptor binding
0.47	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.42	GO:0042803	protein homodimerization activity

0.41	GO:0002080	acrosomal membrane
0.37	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q8IYW2|CFA46_HUMAN
Cilia- and flagella-associated protein 46
Search

CFAP46

0.89	Cilia- and flagella-associated protein 46

0.70	GO:0060294	cilium movement involved in cell motility
0.53	GO:0035082	axoneme assembly

0.75	GO:0005929	cilium
0.64	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.56	GO:0044430	cytoskeletal part

sp|Q8IYW4|ENTD1_HUMAN
ENTH domain-containing protein 1
Search

ENTHD1

0.97	ENTH domain-containing protein 1

0.75	GO:1903671	negative regulation of sprouting angiogenesis
0.68	GO:0007565	female pregnancy
0.66	GO:0001701	in utero embryonic development
0.65	GO:0007219	Notch signaling pathway
0.64	GO:0048568	embryonic organ development
0.51	GO:0006897	endocytosis
0.42	GO:1905443	regulation of clathrin coat assembly
0.40	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.39	GO:0031334	positive regulation of protein complex assembly
0.37	GO:0006397	mRNA processing

0.43	GO:0008289	lipid binding
0.40	GO:0035615	clathrin adaptor activity
0.40	GO:0044325	ion channel binding
0.38	GO:0008134	transcription factor binding
0.35	GO:0003723	RNA binding

0.61	GO:0005829	cytosol
0.53	GO:0030128	clathrin coat of endocytic vesicle
0.45	GO:0005905	clathrin-coated pit
0.42	GO:0098890	extrinsic component of postsynaptic membrane
0.42	GO:0098888	extrinsic component of presynaptic membrane
0.41	GO:0005634	nucleus
0.40	GO:0043195	terminal bouton
0.39	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IYW5|RN168_HUMAN
E3 ubiquitin-protein ligase RNF168
Search

RNF168

0.96	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF168

0.80	GO:0033522	histone H2A ubiquitination
0.78	GO:0045739	positive regulation of DNA repair
0.75	GO:0010212	response to ionizing radiation
0.73	GO:0006302	double-strand break repair
0.64	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.63	GO:0070534	protein K63-linked ubiquitination
0.61	GO:0010390	histone monoubiquitination
0.55	GO:0006511	ubiquitin-dependent protein catabolic process
0.45	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.44	GO:0002312	B cell activation involved in immune response

0.74	GO:0043130	ubiquitin binding
0.73	GO:0042393	histone binding
0.71	GO:0004842	ubiquitin-protein transferase activity
0.70	GO:0003682	chromatin binding
0.63	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.53	GO:0044877	macromolecular complex binding
0.52	GO:0016874	ligase activity
0.51	GO:0046872	metal ion binding

0.69	GO:0000151	ubiquitin ligase complex
0.61	GO:0035861	site of double-strand break
0.57	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0043234	protein complex
0.37	GO:1990391	DNA repair complex
0.30	GO:0016020	membrane

0.52	EC:6	GO:0016874
0.71	KEGG:R03876	GO:0004842

sp|Q8IYX0|ZN679_HUMAN
Zinc finger protein 679
Search

0.86	Zinc finger protein 98

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0070895	negative regulation of transposon integration
0.36	GO:0021762	substantia nigra development
0.34	GO:1902679	negative regulation of RNA biosynthetic process

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.30	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|Q8IYX1|TBC21_HUMAN
TBC1 domain family member 21
Search

TBC1D21

0.97	TBC1 domain family member 21 isoform A

0.66	GO:0031338	regulation of vesicle fusion
0.66	GO:0090630	activation of GTPase activity
0.56	GO:0006886	intracellular protein transport
0.49	GO:1902017	regulation of cilium assembly
0.44	GO:0007283	spermatogenesis
0.41	GO:0030154	cell differentiation
0.34	GO:0055114	oxidation-reduction process

0.71	GO:0003779	actin binding
0.65	GO:0017137	Rab GTPase binding
0.61	GO:0005096	GTPase activator activity
0.37	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.36	GO:0005507	copper ion binding

0.82	GO:0001669	acrosomal vesicle
0.47	GO:0070062	extracellular exosome
0.41	GO:0005856	cytoskeleton

0.37

EC:1.4.3

GO:0016641

sp|Q8IYX3|CC116_HUMAN
Coiled-coil domain-containing protein 116
Search

CCDC116

0.97	Coiled-coil domain-containing protein 116

0.41

GO:0005515

protein binding

0.77	GO:0005813	centrosome
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q8IYX4|DND1_HUMAN
Dead end protein homolog 1
Search

DND1

0.97	DND microRNA-mediated repression inhibitor 1

0.62	GO:0060965	negative regulation of gene silencing by miRNA
0.59	GO:0016554	cytidine to uridine editing
0.57	GO:0007281	germ cell development
0.42	GO:0002244	hematopoietic progenitor cell differentiation
0.37	GO:0006418	tRNA aminoacylation for protein translation
0.34	GO:2000742	regulation of anterior head development
0.34	GO:0008354	germ cell migration
0.34	GO:0048255	mRNA stabilization
0.34	GO:0060047	heart contraction
0.33	GO:2000145	regulation of cell motility

0.61	GO:0017091	AU-rich element binding
0.41	GO:0035198	miRNA binding
0.37	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.37	GO:0140101	catalytic activity, acting on a tRNA
0.36	GO:0003729	mRNA binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0005515	protein binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.38	GO:0019013	viral nucleocapsid
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.37

EC:6.1

GO:0016875

sp|Q8IYX7|SAXO1_HUMAN
Stabilizer of axonemal microtubules 1
Search

SAXO1

0.94	Stabilizer of axonemal microtubules 1

0.60	GO:0009631	cold acclimation
0.60	GO:0045724	positive regulation of cilium assembly
0.57	GO:0070417	cellular response to cold
0.55	GO:0050821	protein stabilization
0.37	GO:0030030	cell projection organization

0.74

GO:0008017

microtubule binding

0.61	GO:0005879	axonemal microtubule
0.57	GO:0036126	sperm flagellum
0.56	GO:0036064	ciliary basal body
0.56	GO:0005814	centriole

sp|Q8IYX8|CE57L_HUMAN
Centrosomal protein CEP57L1
Search

CEP57L1

0.97	Centrosomal protein 57 like 1

0.49	GO:0034453	microtubule anchoring
0.48	GO:0000070	mitotic sister chromatid segregation
0.35	GO:0000060	protein import into nucleus, translocation
0.33	GO:0008543	fibroblast growth factor receptor signaling pathway
0.33	GO:0007286	spermatid development
0.33	GO:0051260	protein homooligomerization

0.81	GO:0043015	gamma-tubulin binding
0.73	GO:0042802	identical protein binding
0.72	GO:0008017	microtubule binding
0.34	GO:0017134	fibroblast growth factor binding
0.33	GO:0046983	protein dimerization activity

0.47	GO:0005813	centrosome
0.37	GO:0005874	microtubule
0.33	GO:0005737	cytoplasm
0.32	GO:0012505	endomembrane system
0.32	GO:0005634	nucleus

sp|Q8IYY4|DZI1L_HUMAN
Zinc finger protein DZIP1L
Search

DZIP1L

0.96	DAZ interacting zinc finger protein 1 like

0.63	GO:0060271	cilium assembly
0.56	GO:0032880	regulation of protein localization
0.39	GO:0051220	cytoplasmic sequestering of protein
0.38	GO:0007224	smoothened signaling pathway
0.35	GO:0045184	establishment of protein localization
0.34	GO:0097359	UDP-glucosylation
0.34	GO:0010620	negative regulation of transcription by transcription factor catabolism
0.34	GO:0008589	regulation of smoothened signaling pathway
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:0009101	glycoprotein biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.34	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity

0.65	GO:0036064	ciliary basal body
0.61	GO:0005814	centriole
0.39	GO:0097539	ciliary transition fiber
0.36	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

GO:0003980

sp|Q8IZ02|LRC34_HUMAN
Leucine-rich repeat-containing protein 34
Search

LRRC34

0.93	Leucine-rich repeat-containing protein 34

0.69	GO:0030154	cell differentiation
0.41	GO:0006412	translation

0.42

GO:0003735

structural constituent of ribosome

0.70	GO:0005730	nucleolus
0.49	GO:0005737	cytoplasm
0.41	GO:1990904	ribonucleoprotein complex

sp|Q8IZ07|AN13A_HUMAN
Ankyrin repeat domain-containing protein 13A
Search

ANKRD13A

0.95	Ankyrin repeat domain-containing protein 13A

0.36	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0006914	autophagy

0.36	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0004725	protein tyrosine phosphatase activity

0.53	GO:0005886	plasma membrane
0.43	GO:0005770	late endosome
0.30	GO:0044425	membrane part

0.36

EC:3.1.3

GO:0008138

sp|Q8IZ08|GP135_HUMAN
Probable G-protein coupled receptor 135
Search

GPR135

0.97	Leukocyte platelet-activating factor receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0001696	gastric acid secretion
0.41	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0008284	positive regulation of cell proliferation
0.40	GO:0048565	digestive tract development
0.40	GO:0048732	gland development
0.34	GO:0045907	positive regulation of vasoconstriction
0.33	GO:0007610	behavior
0.33	GO:0090274	positive regulation of somatostatin secretion
0.33	GO:0001821	histamine secretion

0.72	GO:0004930	G-protein coupled receptor activity
0.46	GO:0001653	peptide receptor activity
0.43	GO:0031741	type B gastrin/cholecystokinin receptor binding
0.38	GO:0050346	trans-L-3-hydroxyproline dehydratase activity
0.34	GO:0030594	neurotransmitter receptor activity
0.33	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity
0.33	GO:0004435	phosphatidylinositol phospholipase C activity
0.32	GO:0005216	ion channel activity

0.44	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.38	EC:4.2.1.77	GO:0050346
0.38	KEGG:R04374	GO:0050346

sp|Q8IZ13|ZBED8_HUMAN
Protein ZBED8
Search

ZBED8

0.97	Zinc finger BED-type containing 8

0.53

GO:0006357

regulation of transcription by RNA polymerase II

0.54	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.44	GO:0003677	DNA binding
0.41	GO:0046983	protein dimerization activity

0.68	GO:0005654	nucleoplasm
0.41	GO:0005737	cytoplasm

sp|Q8IZ16|CG061_HUMAN
Uncharacterized protein C7orf61
Search

sp|Q8IZ20|ZN683_HUMAN
Tissue-resident T-cell transcription regulator protein ZNF683
Search

ZNF683

0.52	Tissue-resident T-cell transcription regulator protein ZNF683

0.56	GO:0033082	regulation of extrathymic T cell differentiation
0.54	GO:0051136	regulation of NK T cell differentiation
0.54	GO:0032823	regulation of natural killer cell differentiation
0.48	GO:1990654	sebum secreting cell proliferation
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0048513	animal organ development
0.47	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.47	GO:0060576	intestinal epithelial cell development
0.47	GO:0045579	positive regulation of B cell differentiation
0.47	GO:0030889	negative regulation of B cell proliferation

0.52	GO:1990841	promoter-specific chromatin binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0042826	histone deacetylase binding
0.38	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.34	GO:0046872	metal ion binding
0.32	GO:0008168	methyltransferase activity

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

0.32

GO:0008168

sp|Q8IZ21|PHAR4_HUMAN
Phosphatase and actin regulator 4
Search

PHACTR4

0.76	Phosphatase and actin regulator

0.81	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.62	GO:2001045	negative regulation of integrin-mediated signaling pathway
0.61	GO:0061386	closure of optic fissure
0.59	GO:0048484	enteric nervous system development
0.58	GO:0001755	neural crest cell migration
0.58	GO:0001843	neural tube closure
0.57	GO:0007266	Rho protein signal transduction
0.52	GO:0030036	actin cytoskeleton organization
0.52	GO:0051726	regulation of cell cycle
0.51	GO:0043085	positive regulation of catalytic activity

0.84	GO:0008157	protein phosphatase 1 binding
0.81	GO:0004864	protein phosphatase inhibitor activity
0.73	GO:0003779	actin binding
0.60	GO:0072542	protein phosphatase activator activity
0.33	GO:0005199	structural constituent of cell wall

0.56	GO:0030027	lamellipodium
0.38	GO:0005622	intracellular

sp|Q8IZ26|ZNF34_HUMAN
Zinc finger protein 34
Search

ZNF34

0.65	Zinc finger domain-containing protein (Fragment)

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0044789	modulation by host of viral release from host cell
0.36	GO:1902188	positive regulation of viral release from host cell
0.36	GO:0044794	positive regulation by host of viral process
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.33	GO:0007275	multicellular organism development

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.45	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.42	GO:0031974	membrane-enclosed lumen
0.41	GO:0043227	membrane-bounded organelle
0.39	GO:0044422	organelle part
0.34	GO:1990904	ribonucleoprotein complex
0.34	GO:0043228	non-membrane-bounded organelle

sp|Q8IZ40|RCOR2_HUMAN
REST corepressor 2
Search

RCOR2

0.95	REST corepressor 2

0.49	GO:0045892	negative regulation of transcription, DNA-templated
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated

0.54	GO:0003677	DNA binding
0.54	GO:0003714	transcription corepressor activity
0.47	GO:0019899	enzyme binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.44	GO:0008134	transcription factor binding
0.34	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.34	GO:0001104	RNA polymerase II transcription cofactor activity

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.47	GO:0017053	transcriptional repressor complex
0.34	GO:0000785	chromatin

sp|Q8IZ41|RASEF_HUMAN
Ras and EF-hand domain-containing protein
Search

RASEF

0.89	RAS and EF-hand domain containing

0.52

GO:0051260

protein homooligomerization

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.61	GO:0005509	calcium ion binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042802	identical protein binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005829	cytosol

sp|Q8IZ52|CHSS2_HUMAN
Chondroitin sulfate synthase 2
Search

CHPF

0.55	Hexosyltransferase

0.54

GO:0030206

chondroitin sulfate biosynthetic process

0.85	GO:0008376	acetylgalactosaminyltransferase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

GO:0008376

sp|Q8IZ57|NRSN1_HUMAN
Neurensin-1
Search

NRSN1

0.97	Vesicular membrane protein of 24 kDa

0.72

GO:0007399

nervous system development

0.33

GO:0005515

protein binding

0.77	GO:0030133	transport vesicle
0.57	GO:0043025	neuronal cell body
0.57	GO:0030426	growth cone
0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q8IZ63|PRR22_HUMAN
Proline-rich protein 22
Search

PRR22

0.97	Proline-rich protein 22

sp|Q8IZ69|TRM2A_HUMAN
tRNA (uracil-5-)-methyltransferase homolog A
Search

TRMT2A

0.95	tRNA (Uracil-5-)-methyltransferase like protein A

0.67	GO:0001510	RNA methylation
0.61	GO:0006396	RNA processing

0.67	GO:0008173	RNA methyltransferase activity
0.55	GO:0003723	RNA binding
0.33	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.33	GO:0140101	catalytic activity, acting on a tRNA

0.30

GO:0031224

intrinsic component of membrane

0.67

GO:0008173

sp|Q8IZ73|RUSD2_HUMAN
RNA pseudouridylate synthase domain-containing protein 2
Search

RPUSD2

0.94	RNA pseudouridylate synthase domain-containing protein 2

0.72	GO:0001522	pseudouridine synthesis
0.50	GO:0000154	rRNA modification
0.34	GO:0008213	protein alkylation
0.34	GO:0043414	macromolecule methylation

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding
0.50	GO:0019239	deaminase activity
0.35	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity

0.72

EC:5.4.99.12

GO:0009982

sp|Q8IZ81|ELMD2_HUMAN
ELMO domain-containing protein 2
Search

ELMOD2

0.96	ELMO domain-containing protein 2

0.75	GO:0043547	positive regulation of GTPase activity
0.56	GO:0050688	regulation of defense response to virus
0.35	GO:0051607	defense response to virus
0.35	GO:1903955	positive regulation of protein targeting to mitochondrion
0.34	GO:0031647	regulation of protein stability
0.33	GO:0090175	regulation of establishment of planar polarity
0.33	GO:0000281	mitotic cytokinesis

0.76

GO:0005096

GTPase activator activity

0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q8IZ83|A16A1_HUMAN
Aldehyde dehydrogenase family 16 member A1
Search

ALDH16A1

0.39	NAD-dependent aldehyde dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.38	GO:0010469	regulation of receptor activity
0.36	GO:0009450	gamma-aminobutyric acid catabolic process
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process
0.32	GO:0055085	transmembrane transport

0.73	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.39	GO:0005125	cytokine activity
0.37	GO:0009013	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
0.35	GO:0003735	structural constituent of ribosome
0.33	GO:0015293	symporter activity

0.38	GO:0070062	extracellular exosome
0.36	GO:0015934	large ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

0.73

EC:1.2.1.3

GO:0004029

sp|Q8IZ96|CKLF1_HUMAN
CKLF-like MARVEL transmembrane domain-containing protein 1
Search

CMTM1

0.81	CKLF like MARVEL transmembrane domain containing 1

0.47	GO:0010469	regulation of receptor activity
0.45	GO:0006935	chemotaxis

0.49

GO:0005125

cytokine activity

0.46	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|Q8IZA0|K319L_HUMAN
Dyslexia-associated protein KIAA0319-like protein
Search

KIAA0319L

0.96	Dyslexia susceptibility 2-like

0.38	GO:2000171	negative regulation of dendrite development
0.37	GO:0001764	neuron migration

0.30

GO:0005515

protein binding

0.44	GO:0031410	cytoplasmic vesicle
0.39	GO:0070062	extracellular exosome
0.38	GO:0012505	endomembrane system
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.36	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IZA3|H1FOO_HUMAN
Histone H1oo
Search

H1FOO

0.97	Oocyte-specific H1 histone

0.79	GO:0006334	nucleosome assembly
0.67	GO:2000737	negative regulation of stem cell differentiation
0.67	GO:0044030	regulation of DNA methylation
0.66	GO:0016584	nucleosome positioning

0.66	GO:0031492	nucleosomal DNA binding
0.35	GO:0046982	protein heterodimerization activity

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.54	GO:0031974	membrane-enclosed lumen
0.38	GO:0070062	extracellular exosome

sp|Q8IZC4|RTKN2_HUMAN
Rhotekin-2
Search

RTKN2

0.97	Rhotekin-2

0.74	GO:0030097	hemopoiesis
0.58	GO:0007165	signal transduction
0.56	GO:0032185	septin cytoskeleton organization
0.36	GO:0008284	positive regulation of cell proliferation
0.35	GO:0034260	negative regulation of GTPase activity
0.34	GO:0042981	regulation of apoptotic process
0.33	GO:0006915	apoptotic process

0.57	GO:0017049	GTP-Rho binding
0.35	GO:0005095	GTPase inhibitor activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane

sp|Q8IZC6|CORA1_HUMAN
Collagen alpha-1(XXVII) chain
Search

COL27A1

0.82	Collagen type XXVII alpha 1 chain

0.63	GO:0003431	growth plate cartilage chondrocyte development
0.57	GO:0030198	extracellular matrix organization
0.40	GO:0002244	hematopoietic progenitor cell differentiation
0.37	GO:0048570	notochord morphogenesis
0.37	GO:0030282	bone mineralization

0.79	GO:0005201	extracellular matrix structural constituent
0.35	GO:0046872	metal ion binding

0.73	GO:0005581	collagen trimer
0.62	GO:0098643	banded collagen fibril
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IZC7|ZN101_HUMAN
Zinc finger protein 101
Search

0.81	Zinc finger protein 14

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.36	GO:0014022	neural plate elongation
0.35	GO:0060029	convergent extension involved in organogenesis
0.35	GO:0060028	convergent extension involved in axis elongation
0.35	GO:0060669	embryonic placenta morphogenesis
0.35	GO:0060027	convergent extension involved in gastrulation
0.34	GO:0051253	negative regulation of RNA metabolic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.38	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|Q8IZD0|SAM14_HUMAN
Sterile alpha motif domain-containing protein 14
Search

SAMD14

0.97	Sterile alpha motif domain-containing protein 14

0.67	GO:0050804	modulation of chemical synaptic transmission
0.63	GO:0042127	regulation of cell proliferation
0.55	GO:0019722	calcium-mediated signaling
0.51	GO:0007015	actin filament organization
0.37	GO:0006265	DNA topological change
0.35	GO:0006508	proteolysis

0.70	GO:0008157	protein phosphatase 1 binding
0.61	GO:0003779	actin binding
0.38	GO:0061505	DNA topoisomerase II activity
0.37	GO:0008094	DNA-dependent ATPase activity
0.37	GO:0004252	serine-type endopeptidase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0043197	dendritic spine
0.56	GO:0030175	filopodium
0.54	GO:0030864	cortical actin cytoskeleton
0.30	GO:0016020	membrane

0.37

GO:0004252

sp|Q8IZD2|KMT2E_HUMAN
Histone-lysine N-methyltransferase 2E
Search

KMT2E

0.73	Histone-lysine N-methyltransferase MLL5

0.58	GO:1905437	positive regulation of histone H3-K4 trimethylation
0.55	GO:0002446	neutrophil mediated immunity
0.54	GO:0042119	neutrophil activation
0.54	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.53	GO:0030218	erythrocyte differentiation
0.52	GO:0032259	methylation
0.49	GO:0006305	DNA alkylation
0.49	GO:0044728	DNA methylation or demethylation
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0045010	actin nucleation

0.53	GO:0035064	methylated histone binding
0.53	GO:0046872	metal ion binding
0.47	GO:0019899	enzyme binding
0.47	GO:0008168	methyltransferase activity
0.36	GO:0052795	exo-alpha-(2->6)-sialidase activity
0.36	GO:0052796	exo-alpha-(2->8)-sialidase activity
0.36	GO:0052794	exo-alpha-(2->3)-sialidase activity
0.35	GO:0008017	microtubule binding
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0003713	transcription coactivator activity

0.53	GO:0035327	transcriptionally active chromatin
0.43	GO:0005634	nucleus
0.43	GO:0043234	protein complex
0.35	GO:0005884	actin filament
0.32	GO:0070013	intracellular organelle lumen
0.31	GO:0005886	plasma membrane
0.31	GO:0005737	cytoplasm

0.47

GO:0008168

sp|Q8IZD4|DCP1B_HUMAN
mRNA-decapping enzyme 1B
Search

DCP1B

0.84	DCP1 decapping enzyme homolog B

0.84	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.73	GO:0043085	positive regulation of catalytic activity
0.54	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA

0.75	GO:0008047	enzyme activator activity
0.49	GO:0003729	mRNA binding

0.57	GO:0005829	cytosol
0.51	GO:0000932	P-body
0.48	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q8IZD6|S22AF_HUMAN
Solute carrier family 22 member 15
Search

SLC22A15

0.97	Solute carrier family 22 (Organic cation transporter), member 15

0.54	GO:0055085	transmembrane transport
0.43	GO:0015711	organic anion transport

0.56

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|Q8IZD9|DOCK3_HUMAN
Dedicator of cytokinesis protein 3
Search

DOCK3

0.95	Dedicator of cytokinesis protein 3

0.76	GO:0007264	small GTPase mediated signal transduction
0.65	GO:0065009	regulation of molecular function

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.37	GO:0017124	SH3 domain binding

0.45

GO:0005829

cytosol

sp|Q8IZE3|PACE1_HUMAN
Protein-associating with the carboxyl-terminal domain of ezrin
Search

SCYL3

0.92	Protein-associating with the carboxyl-terminal domain of ezrin

0.63	GO:0006468	protein phosphorylation
0.38	GO:0016477	cell migration

0.63	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0019894	kinesin binding

0.44	GO:0030027	lamellipodium
0.41	GO:0005794	Golgi apparatus
0.36	GO:0005871	kinesin complex
0.30	GO:0044425	membrane part

sp|Q8IZF0|NALCN_HUMAN
Sodium leak channel non-selective protein
Search

NALCN

0.94	Brain voltage-gated cation channel

0.61	GO:0098655	cation transmembrane transport
0.50	GO:0086010	membrane depolarization during action potential
0.46	GO:0006816	calcium ion transport
0.40	GO:0060075	regulation of resting membrane potential
0.38	GO:0034765	regulation of ion transmembrane transport
0.37	GO:0071804	cellular potassium ion transport
0.37	GO:0006814	sodium ion transport
0.35	GO:0098660	inorganic ion transmembrane transport
0.34	GO:0030866	cortical actin cytoskeleton organization

0.74	GO:0005261	cation channel activity
0.39	GO:0022842	narrow pore channel activity
0.37	GO:0022832	voltage-gated channel activity
0.37	GO:0015081	sodium ion transmembrane transporter activity
0.37	GO:0022839	ion gated channel activity
0.37	GO:0008381	mechanosensitive ion channel activity
0.35	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.39	GO:0005886	plasma membrane
0.33	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

sp|Q8IZF2|AGRF5_HUMAN
Adhesion G protein-coupled receptor F5
Search

ADGRF5

0.86	Adhesion G protein-coupled receptor F5

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0043129	surfactant homeostasis
0.59	GO:0043031	negative regulation of macrophage activation
0.58	GO:0071073	positive regulation of phospholipid biosynthetic process
0.57	GO:0045444	fat cell differentiation
0.55	GO:0042593	glucose homeostasis
0.52	GO:0006112	energy reserve metabolic process
0.35	GO:0032793	positive regulation of CREB transcription factor activity
0.35	GO:0007416	synapse assembly

0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0009881	photoreceptor activity

0.55	GO:0045177	apical part of cell
0.52	GO:0009986	cell surface
0.51	GO:0031410	cytoplasmic vesicle
0.36	GO:0005886	plasma membrane
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q8IZF3|AGRF4_HUMAN
Adhesion G protein-coupled receptor F4
Search

0.97	Adhesion G protein-coupled receptor F4

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0032793	positive regulation of CREB transcription factor activity
0.44	GO:0007416	synapse assembly
0.44	GO:0007613	memory
0.44	GO:0019933	cAMP-mediated signaling
0.42	GO:0031175	neuron projection development
0.36	GO:0043129	surfactant homeostasis
0.36	GO:0043031	negative regulation of macrophage activation
0.36	GO:0071073	positive regulation of phospholipid biosynthetic process

0.72	GO:0004930	G-protein coupled receptor activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0005515	protein binding
0.32	GO:0009881	photoreceptor activity

0.37	GO:0005886	plasma membrane
0.35	GO:0045177	apical part of cell
0.35	GO:0009986	cell surface
0.34	GO:0031410	cytoplasmic vesicle
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q8IZF4|AGRG5_HUMAN
Adhesion G-protein coupled receptor G5
Search

ADGRG5

0.96	Adhesion G-protein coupled receptor G5

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0010573	vascular endothelial growth factor production
0.50	GO:2001223	negative regulation of neuron migration
0.50	GO:0021819	layer formation in cerebral cortex
0.50	GO:0070528	protein kinase C signaling
0.50	GO:0021796	cerebral cortex regionalization
0.49	GO:0035025	positive regulation of Rho protein signal transduction
0.49	GO:0072520	seminiferous tubule development
0.48	GO:2000179	positive regulation of neural precursor cell proliferation

0.72	GO:0004930	G-protein coupled receptor activity
0.48	GO:0050840	extracellular matrix binding
0.48	GO:0005518	collagen binding
0.48	GO:0008201	heparin binding
0.34	GO:0030246	carbohydrate binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0097451	glial limiting end-foot
0.38	GO:0045121	membrane raft
0.36	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.34	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

sp|Q8IZF5|AGRF3_HUMAN
Adhesion G-protein coupled receptor F3
Search

ADGRF3

0.97	Adhesion G-protein coupled receptor F3

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0006631	fatty acid metabolic process
0.35	GO:0032793	positive regulation of CREB transcription factor activity
0.35	GO:0007416	synapse assembly
0.35	GO:0007613	memory
0.35	GO:0019933	cAMP-mediated signaling
0.34	GO:0031175	neuron projection development
0.33	GO:0055114	oxidation-reduction process
0.31	GO:0006950	response to stress

0.72	GO:0004930	G-protein coupled receptor activity
0.36	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity

0.32	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.36

EC:1.1.1.35

GO:0003857

sp|Q8IZF6|AGRG4_HUMAN
Adhesion G-protein coupled receptor G4
Search

ADGRG4

0.86	LOW QUALITY PROTEIN: adhesion G-protein coupled receptor G4

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0005977	glycogen metabolic process
0.34	GO:0007283	spermatogenesis
0.33	GO:0016310	phosphorylation

0.72	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005516	calmodulin binding
0.33	GO:0016301	kinase activity

0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.38	GO:0045177	apical part of cell
0.36	GO:0070062	extracellular exosome
0.35	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q8IZF7|AGRF2_HUMAN
Adhesion G-protein coupled receptor F2
Search

ADGRF2

0.97	Adhesion G-protein coupled receptor F2

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0043129	surfactant homeostasis
0.51	GO:0043031	negative regulation of macrophage activation
0.51	GO:0071073	positive regulation of phospholipid biosynthetic process
0.50	GO:0045444	fat cell differentiation
0.48	GO:0042593	glucose homeostasis
0.46	GO:0006112	energy reserve metabolic process

0.72

GO:0004930

G-protein coupled receptor activity

0.48	GO:0045177	apical part of cell
0.46	GO:0009986	cell surface
0.45	GO:0031410	cytoplasmic vesicle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IZH2|XRN1_HUMAN
5'-3' exoribonuclease 1
Search

XRN1

0.79	5'-3' exoribonuclease 1

0.75	GO:0000956	nuclear-transcribed mRNA catabolic process
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.61	GO:0008334	histone mRNA metabolic process
0.59	GO:0071027	nuclear RNA surveillance
0.55	GO:0016075	rRNA catabolic process
0.41	GO:1905795	cellular response to puromycin
0.40	GO:0071409	cellular response to cycloheximide
0.40	GO:0033574	response to testosterone
0.38	GO:0017148	negative regulation of translation
0.36	GO:0032211	negative regulation of telomere maintenance via telomerase

0.74	GO:0008409	5'-3' exonuclease activity
0.54	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters
0.52	GO:0003723	RNA binding
0.40	GO:0051880	G-quadruplex DNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.50	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.44	GO:0005886	plasma membrane
0.40	GO:0000932	P-body
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

0.54

EC:3.1.13

GO:0016896

sp|Q8IZI9|IFNL3_HUMAN
Interferon lambda-3
Search

0.97	Interferon lambda

0.85	GO:0007259	JAK-STAT cascade
0.79	GO:0050778	positive regulation of immune response
0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0050863	regulation of T cell activation
0.54	GO:0045087	innate immune response
0.52	GO:0045345	positive regulation of MHC class I biosynthetic process
0.52	GO:0032696	negative regulation of interleukin-13 production
0.51	GO:0032714	negative regulation of interleukin-5 production
0.51	GO:0002829	negative regulation of type 2 immune response

0.81	GO:0005125	cytokine activity
0.53	GO:0032003	interleukin-28 receptor binding

0.52	GO:0032002	interleukin-28 receptor complex
0.52	GO:0005615	extracellular space
0.45	GO:0005622	intracellular

sp|Q8IZJ0|IFNL2_HUMAN
Interferon lambda-2
Search

0.97	Interferon lambda

0.85	GO:0007259	JAK-STAT cascade
0.79	GO:0050778	positive regulation of immune response
0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0050863	regulation of T cell activation
0.55	GO:0045087	innate immune response
0.52	GO:0045345	positive regulation of MHC class I biosynthetic process
0.52	GO:0032696	negative regulation of interleukin-13 production
0.52	GO:0032714	negative regulation of interleukin-5 production
0.51	GO:0002829	negative regulation of type 2 immune response

0.81	GO:0005125	cytokine activity
0.53	GO:0032003	interleukin-28 receptor binding

0.52	GO:0032002	interleukin-28 receptor complex
0.52	GO:0005615	extracellular space
0.45	GO:0005622	intracellular

sp|Q8IZJ1|UNC5B_HUMAN
Netrin receptor UNC5B
Search

UNC5B

0.97	Unc-5 netrin receptor B

0.85	GO:0038007	netrin-activated signaling pathway
0.59	GO:0033564	anterior/posterior axon guidance
0.56	GO:1901099	negative regulation of signal transduction in absence of ligand
0.55	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.55	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.54	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.54	GO:0043524	negative regulation of neuron apoptotic process
0.45	GO:0001569	branching involved in blood vessel morphogenesis
0.44	GO:0016525	negative regulation of angiogenesis
0.41	GO:0043065	positive regulation of apoptotic process

0.85	GO:0005042	netrin receptor activity
0.37	GO:0005515	protein binding
0.34	GO:0005337	nucleoside transmembrane transporter activity

0.38	GO:0045121	membrane raft
0.37	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q8IZJ3|CPMD8_HUMAN
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8
Search

CPAMD8

0.95	C3 and PZP like, alpha-2-macroglobulin domain containing 8

0.74	GO:0010951	negative regulation of endopeptidase activity
0.53	GO:0001654	eye development

0.75

GO:0004866

endopeptidase inhibitor activity

0.72	GO:0005615	extracellular space
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IZJ4|RGDSR_HUMAN
Ral-GDS-related protein
Search

RGL4

0.97	Ral guanine nucleotide dissociation stimulator like 4

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.34	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.33	GO:0006289	nucleotide-excision repair
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0007166	cell surface receptor signaling pathway
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.43	GO:0030695	GTPase regulator activity
0.35	GO:0017160	Ral GTPase binding
0.33	GO:0003684	damaged DNA binding
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0004930	G-protein coupled receptor activity

0.46	GO:0005903	brush border
0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.33

GO:0016491

sp|Q8IZJ6|TDH_HUMAN
Inactive L-threonine 3-dehydrogenase, mitochondrial
Search

TDH

0.54	L-threonine dehydrogenase

0.49	GO:0006567	threonine catabolic process
0.39	GO:0055114	oxidation-reduction process
0.37	GO:0006544	glycine metabolic process
0.37	GO:0042737	drug catabolic process

0.60	GO:0050662	coenzyme binding
0.51	GO:0008743	L-threonine 3-dehydrogenase activity
0.47	GO:0042802	identical protein binding

0.42	GO:0005739	mitochondrion
0.33	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

0.51	EC:1.1.1.103	GO:0008743
0.51	KEGG:R01465	GO:0008743

sp|Q8IZK6|MCLN2_HUMAN
Mucolipin-2
Search

MCOLN2

0.89	Mucolipin-2 isoform B

0.59	GO:0071642	positive regulation of macrophage inflammatory protein 1 alpha production
0.59	GO:0035926	chemokine (C-C motif) ligand 2 secretion
0.58	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.58	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.58	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.57	GO:1905517	macrophage migration
0.55	GO:1990266	neutrophil migration
0.50	GO:0042491	inner ear auditory receptor cell differentiation
0.49	GO:0051259	protein oligomerization
0.48	GO:0007626	locomotory behavior

0.37	GO:0005262	calcium channel activity
0.35	GO:0097682	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity
0.34	GO:0008289	lipid binding
0.32	GO:0043168	anion binding

0.54	GO:0055037	recycling endosome
0.39	GO:0005886	plasma membrane
0.38	GO:0005765	lysosomal membrane
0.38	GO:0010008	endosome membrane
0.37	GO:0005770	late endosome
0.36	GO:0000421	autophagosome membrane
0.35	GO:0005769	early endosome
0.34	GO:0031166	integral component of vacuolar membrane
0.34	GO:0032420	stereocilium
0.34	GO:0031252	cell leading edge

sp|Q8IZL2|MAML2_HUMAN
Mastermind-like protein 2
Search

MAML2

0.93	Mastermind like transcriptional coactivator 2

0.81	GO:0007219	Notch signaling pathway
0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0045747	positive regulation of Notch signaling pathway
0.42	GO:0006367	transcription initiation from RNA polymerase II promoter

0.79

GO:0003713

transcription coactivator activity

0.68	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

sp|Q8IZL8|PELP1_HUMAN
Proline-, glutamic acid- and leucine-rich protein 1
Search

PELP1

0.91	Proline, glutamate and leucine rich protein 1

0.86

GO:0071391

cellular response to estrogen stimulus

0.63

GO:0005730

nucleolus

sp|Q8IZL9|CDK20_HUMAN
Cyclin-dependent kinase 20
Search

CDK20

0.96	Cell division protein kinase 20

0.63	GO:0006468	protein phosphorylation
0.50	GO:1904031	positive regulation of cyclin-dependent protein kinase activity
0.42	GO:0060271	cilium assembly
0.38	GO:0051301	cell division
0.38	GO:0007275	multicellular organism development
0.38	GO:0007049	cell cycle
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation

0.69	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019912	cyclin-dependent protein kinase activating kinase activity
0.51	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.34	GO:0005515	protein binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.69	GO:0070985	TFIIK complex
0.40	GO:0005929	cilium
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.7.11.23

GO:0008353

sp|Q8IZM0|CNG1O_HUMAN
Putative CNGA1-overlapping antisense gene protein
Search

0.44	Putative CNGA1-overlapping antisense gene protein

sp|Q8IZM8|ZN654_HUMAN
Zinc finger protein 654
Search

ZNF654

0.76	Zinc finger protein 654

0.36	GO:0097659	nucleic acid-templated transcription
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding

0.36

GO:0005634

nucleus

sp|Q8IZM9|S38A6_HUMAN
Probable sodium-coupled neutral amino acid transporter 6
Search

SLC38A6

0.93	Probable sodium-coupled neutral amino acid transporter 6

0.45	GO:0003333	amino acid transmembrane transport
0.37	GO:0006814	sodium ion transport

0.45

GO:0015171

amino acid transmembrane transporter activity

0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8IZN3|ZDH14_HUMAN
Probable palmitoyltransferase ZDHHC14
Search

ZDHHC14

0.57	Palmitoyltransferase

0.55	GO:0018345	protein palmitoylation
0.34	GO:0000281	mitotic cytokinesis
0.33	GO:0006338	chromatin remodeling
0.33	GO:0006897	endocytosis
0.33	GO:0006886	intracellular protein transport

0.78	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0035091	phosphatidylinositol binding
0.32	GO:0003677	DNA binding

0.48	GO:0005783	endoplasmic reticulum
0.34	GO:0071565	nBAF complex
0.34	GO:0016514	SWI/SNF complex
0.30	GO:0016020	membrane

0.78

GO:0019706

sp|Q8IZN7|D107A_HUMAN
Beta-defensin 107
Search

0.63	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium

0.40

GO:0008289

lipid binding

0.66	GO:0005576	extracellular region
0.49	GO:0009986	cell surface

sp|Q8IZP0|ABI1_HUMAN
Abl interactor 1
Search

ABI1

0.86	Abl interactor 1

0.85	GO:0061098	positive regulation of protein tyrosine kinase activity
0.81	GO:0008154	actin polymerization or depolymerization
0.63	GO:0072673	lamellipodium morphogenesis
0.62	GO:0035855	megakaryocyte development
0.60	GO:0001756	somitogenesis
0.60	GO:0048813	dendrite morphogenesis
0.57	GO:0018108	peptidyl-tyrosine phosphorylation
0.40	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.39	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.38	GO:0008285	negative regulation of cell proliferation

0.86	GO:0030296	protein tyrosine kinase activator activity
0.60	GO:0045296	cadherin binding
0.59	GO:0017124	SH3 domain binding
0.56	GO:0032403	protein complex binding
0.37	GO:0008092	cytoskeletal protein binding
0.35	GO:0031492	nucleosomal DNA binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0003735	structural constituent of ribosome

0.64	GO:0032433	filopodium tip
0.64	GO:0031209	SCAR complex
0.61	GO:0030027	lamellipodium
0.56	GO:0043005	neuron projection
0.40	GO:0014069	postsynaptic density
0.39	GO:0070062	extracellular exosome
0.39	GO:0030427	site of polarized growth
0.39	GO:0045211	postsynaptic membrane
0.38	GO:0030054	cell junction
0.37	GO:0005856	cytoskeleton

sp|Q8IZP1|TBC3A_HUMAN
TBC1 domain family member 3
Search

0.97	TBC1 domain family member 3

0.85	GO:0031338	regulation of vesicle fusion
0.84	GO:0090630	activation of GTPase activity
0.69	GO:0006886	intracellular protein transport
0.47	GO:1902017	regulation of cilium assembly

0.81	GO:0017137	Rab GTPase binding
0.76	GO:0005096	GTPase activator activity

0.67	GO:0012505	endomembrane system
0.54	GO:0005886	plasma membrane
0.45	GO:0005622	intracellular
0.42	GO:0031982	vesicle
0.42	GO:0098805	whole membrane
0.42	GO:0098588	bounding membrane of organelle

sp|Q8IZP2|ST134_HUMAN
Putative protein FAM10A4
Search

0.97	Testis secretory sperm-binding protein Li 233m

0.41	GO:0061084	negative regulation of protein refolding
0.39	GO:0051289	protein homotetramerization
0.39	GO:0051085	chaperone cofactor-dependent protein refolding
0.33	GO:0006351	transcription, DNA-templated

0.63	GO:0046983	protein dimerization activity
0.41	GO:0032564	dATP binding
0.40	GO:0030544	Hsp70 protein binding
0.38	GO:0051087	chaperone binding
0.38	GO:0019904	protein domain specific binding
0.38	GO:0032403	protein complex binding
0.37	GO:0042802	identical protein binding
0.37	GO:0051082	unfolded protein binding
0.35	GO:0030674	protein binding, bridging

0.44	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex
0.33	GO:0005634	nucleus

sp|Q8IZP6|R113B_HUMAN
RING finger protein 113B
Search

RNF113A

0.65	Zinc finger protein 183

0.52	GO:0034247	snoRNA splicing
0.49	GO:0045292	mRNA cis splicing, via spliceosome

0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0016874	ligase activity

0.49

GO:0005684

U2-type spliceosomal complex

0.33