Queries 9001 to 10000

GO:0016740

sp|Q15648|MED1_HUMAN
Mediator of RNA polymerase II transcription subunit 1
Search

MED1

0.75	Mediator of RNA polymerase II transcription subunit 1

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.63	GO:0002154	thyroid hormone mediated signaling pathway
0.62	GO:0048822	enucleate erythrocyte development
0.62	GO:0006702	androgen biosynthetic process
0.62	GO:0070318	positive regulation of G0 to G1 transition
0.61	GO:0097067	cellular response to thyroid hormone stimulus
0.61	GO:2000347	positive regulation of hepatocyte proliferation
0.61	GO:0070562	regulation of vitamin D receptor signaling pathway
0.61	GO:0060332	positive regulation of response to interferon-gamma
0.61	GO:0045618	positive regulation of keratinocyte differentiation

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.63	GO:0030375	thyroid hormone receptor coactivator activity
0.62	GO:0042809	vitamin D receptor binding
0.62	GO:0046966	thyroid hormone receptor binding
0.61	GO:0042975	peroxisome proliferator activated receptor binding
0.61	GO:0050693	LBD domain binding
0.61	GO:0042974	retinoic acid receptor binding
0.60	GO:0036033	mediator complex binding
0.59	GO:0016922	ligand-dependent nuclear receptor binding
0.59	GO:0030331	estrogen receptor binding

0.76	GO:0016592	mediator complex
0.52	GO:0005730	nucleolus
0.38	GO:0000151	ubiquitin ligase complex
0.37	GO:0000785	chromatin
0.37	GO:0032993	protein-DNA complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q15649|ZNHI3_HUMAN
Zinc finger HIT domain-containing protein 3
Search

ZNHIT3

0.96	Zinc finger HIT domain-containing protein 3

0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression

0.53	GO:0046872	metal ion binding
0.37	GO:0046966	thyroid hormone receptor binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0003676	nucleic acid binding

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q15650|TRIP4_HUMAN
Activating signal cointegrator 1
Search

TRIP4

0.94	Thyroid hormone receptor interactor 4

0.59	GO:0030520	intracellular estrogen receptor signaling pathway
0.57	GO:0045661	regulation of myoblast differentiation
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.55	GO:1901998	toxin transport
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:0061055	myotome development
0.45	GO:0001966	thigmotaxis
0.44	GO:0007528	neuromuscular junction development

0.62	GO:0008270	zinc ion binding
0.60	GO:0016922	ligand-dependent nuclear receptor binding
0.59	GO:0035035	histone acetyltransferase binding
0.59	GO:0030331	estrogen receptor binding
0.57	GO:0002020	protease binding
0.56	GO:0003713	transcription coactivator activity
0.55	GO:0044389	ubiquitin-like protein ligase binding
0.54	GO:0019901	protein kinase binding
0.35	GO:0008073	ornithine decarboxylase inhibitor activity
0.33	GO:0004082	bisphosphoglycerate mutase activity

0.61	GO:0099053	activating signal cointegrator 1 complex
0.61	GO:0005634	nucleus
0.57	GO:0031594	neuromuscular junction
0.54	GO:0005813	centrosome
0.48	GO:0031974	membrane-enclosed lumen
0.39	GO:0005737	cytoplasm

0.33

EC:5.4.2.4

GO:0004082

sp|Q15651|HMGN3_HUMAN
High mobility group nucleosome-binding domain-containing protein 3
Search

HMGN3

0.97	High mobility group nucleosome-binding domain-containing protein 3

0.78	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0051091	positive regulation of DNA binding transcription factor activity
0.38	GO:0016569	covalent chromatin modification

0.81	GO:0031492	nucleosomal DNA binding
0.36	GO:0046966	thyroid hormone receptor binding

0.68	GO:0000785	chromatin
0.58	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.34	GO:0043233	organelle lumen

sp|Q15652|JHD2C_HUMAN
Probable JmjC domain-containing histone demethylation protein 2C
Search

JMJD1C

0.95	Jumonji domain-containing 1 C splice variant (Fragment)

0.85	GO:0033169	histone H3-K9 demethylation
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:1990636	reproductive senescence
0.47	GO:0036098	male germ-line stem cell population maintenance
0.47	GO:0072520	seminiferous tubule development
0.46	GO:0048468	cell development
0.44	GO:0030855	epithelial cell differentiation
0.43	GO:0030099	myeloid cell differentiation

0.86	GO:0032454	histone demethylase activity (H3-K9 specific)
0.82	GO:0031490	chromatin DNA binding
0.76	GO:0000976	transcription regulatory region sequence-specific DNA binding

0.71	GO:0000785	chromatin
0.60	GO:0005634	nucleus

sp|Q15653|IKBB_HUMAN
NF-kappa-B inhibitor beta
Search

NFKBIB

0.97	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

0.83	GO:0071222	cellular response to lipopolysaccharide
0.42	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.42	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.39	GO:0007165	signal transduction
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0002009	morphogenesis of an epithelium
0.33	GO:0006468	protein phosphorylation
0.33	GO:0045944	positive regulation of transcription by RNA polymerase II
0.32	GO:0006508	proteolysis
0.32	GO:0055114	oxidation-reduction process

0.41	GO:0051059	NF-kappaB binding
0.40	GO:0003713	transcription coactivator activity
0.37	GO:0004871	signal transducer activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0003677	DNA binding
0.33	GO:0001067	regulatory region nucleic acid binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0070001	aspartic-type peptidase activity

0.42	GO:0033256	I-kappaB/NF-kappaB complex
0.41	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.33	GO:1905369	endopeptidase complex

0.33

EC:1.3.1.74

GO:0032440

sp|Q15654|TRIP6_HUMAN
Thyroid receptor-interacting protein 6
Search

TRIP6

0.84	Lipoma-preferred partner

0.70	GO:0008588	release of cytoplasmic sequestered NF-kappaB
0.61	GO:0030335	positive regulation of cell migration
0.39	GO:0007155	cell adhesion
0.38	GO:0007045	cell-substrate adherens junction assembly
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0060030	dorsal convergence
0.33	GO:0055085	transmembrane transport

0.66	GO:0005149	interleukin-1 receptor binding
0.60	GO:0019900	kinase binding
0.54	GO:0046872	metal ion binding
0.38	GO:0046966	thyroid hormone receptor binding
0.36	GO:0003723	RNA binding

0.70	GO:0045323	interleukin-1 receptor complex
0.62	GO:0005925	focal adhesion
0.54	GO:0005829	cytosol
0.39	GO:0005856	cytoskeleton
0.37	GO:0005634	nucleus

sp|Q15661|TRYB1_HUMAN
Tryptase alpha/beta-1
Search

0.80	Mast cell tryptase beta III

0.61	GO:0006508	proteolysis
0.38	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.38	GO:0060672	epithelial cell morphogenesis involved in placental branching
0.37	GO:0022617	extracellular matrix disassembly
0.37	GO:0030216	keratinocyte differentiation
0.37	GO:0001843	neural tube closure
0.36	GO:0050878	regulation of body fluid levels
0.36	GO:0050819	negative regulation of coagulation
0.36	GO:0061045	negative regulation of wound healing
0.35	GO:0006952	defense response

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0008201	heparin binding
0.36	GO:0005515	protein binding
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0005509	calcium ion binding

0.44	GO:0005576	extracellular region
0.37	GO:0042629	mast cell granule
0.37	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0016323	basolateral plasma membrane
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0043025	neuronal cell body
0.32	GO:0031982	vesicle
0.32	GO:0005887	integral component of plasma membrane

0.69

GO:0004252

sp|Q15669|RHOH_HUMAN
Rho-related GTP-binding protein RhoH
Search

RHOH

0.97	GTP-binding protein TTF

0.75	GO:0007264	small GTPase mediated signal transduction
0.59	GO:0045576	mast cell activation
0.58	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.57	GO:0030217	T cell differentiation
0.52	GO:0042326	negative regulation of phosphorylation
0.35	GO:0034260	negative regulation of GTPase activity
0.34	GO:0051056	regulation of small GTPase mediated signal transduction
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.56	GO:0019210	kinase inhibitor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005095	GTPase inhibitor activity
0.34	GO:0017048	Rho GTPase binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0004664	prephenate dehydratase activity

0.58	GO:0001772	immunological synapse
0.45	GO:0005622	intracellular
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.33

EC:4.2.1.51

GO:0004664

sp|Q15672|TWST1_HUMAN
Twist-related protein 1
Search

TWIST1

0.91	Basic helix-loop-helix transcription factor twist

0.55	GO:0045668	negative regulation of osteoblast differentiation
0.52	GO:2000793	cell proliferation involved in heart valve development
0.52	GO:0140051	positive regulation of endocardial cushion to mesenchymal transition
0.52	GO:2000800	regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
0.51	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity
0.51	GO:0033128	negative regulation of histone phosphorylation
0.51	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway
0.51	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis
0.50	GO:0003180	aortic valve morphogenesis
0.50	GO:0032000	positive regulation of fatty acid beta-oxidation

0.68	GO:0046983	protein dimerization activity
0.49	GO:0043425	bHLH transcription factor binding
0.49	GO:0070888	E-box binding
0.46	GO:0019904	protein domain specific binding
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.44	GO:0042802	identical protein binding
0.35	GO:0001158	enhancer sequence-specific DNA binding
0.35	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.35	GO:0003682	chromatin binding

0.47	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex

sp|Q15678|PTN14_HUMAN
Tyrosine-protein phosphatase non-receptor type 14
Search

PTPN14

0.75	Tyrosine-protein phosphatase non-receptor type

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.60	GO:0001946	lymphangiogenesis
0.58	GO:0046825	regulation of protein export from nucleus
0.55	GO:0008285	negative regulation of cell proliferation
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:0001837	epithelial to mesenchymal transition
0.37	GO:0001756	somitogenesis
0.36	GO:0003007	heart morphogenesis
0.35	GO:0071345	cellular response to cytokine stimulus
0.34	GO:0006351	transcription, DNA-templated

0.74	GO:0004725	protein tyrosine phosphatase activity
0.58	GO:0030971	receptor tyrosine kinase binding
0.53	GO:0003712	transcription cofactor activity

0.68	GO:0005856	cytoskeleton
0.50	GO:0005654	nucleoplasm
0.46	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0004725

sp|Q15691|MARE1_HUMAN
Microtubule-associated protein RP/EB family member 1
Search

MAPRE1

0.92	DNA methyltransferase 3 beta

0.79	GO:0070507	regulation of microtubule cytoskeleton organization
0.56	GO:0035372	protein localization to microtubule
0.53	GO:1903031	regulation of microtubule plus-end binding
0.53	GO:0032272	negative regulation of protein polymerization
0.52	GO:1904528	positive regulation of microtubule binding
0.52	GO:1902904	negative regulation of supramolecular fiber organization
0.52	GO:0051494	negative regulation of cytoskeleton organization
0.50	GO:0032273	positive regulation of protein polymerization
0.50	GO:1902905	positive regulation of supramolecular fiber organization
0.49	GO:0051495	positive regulation of cytoskeleton organization

0.84	GO:0051010	microtubule plus-end binding
0.51	GO:0045296	cadherin binding
0.49	GO:0019901	protein kinase binding
0.47	GO:0042802	identical protein binding
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0008168	methyltransferase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0003714	transcription corepressor activity
0.33	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.72	GO:0005874	microtubule
0.56	GO:0030981	cortical microtubule cytoskeleton
0.51	GO:0005819	spindle
0.50	GO:0005815	microtubule organizing center
0.49	GO:0031253	cell projection membrane
0.45	GO:0005794	Golgi apparatus
0.34	GO:0005829	cytosol
0.32	GO:0005654	nucleoplasm

0.34

GO:0008168

sp|Q15695|U2AFL_HUMAN
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1
Search

ZRSR2

0.95	Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 1

0.75	GO:0000398	mRNA splicing, via spliceosome
0.41	GO:0022618	ribonucleoprotein complex assembly

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.84	GO:0089701	U2AF
0.55	GO:0019013	viral nucleocapsid
0.53	GO:1990904	ribonucleoprotein complex
0.36	GO:0031981	nuclear lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q15696|U2AFM_HUMAN
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
Search

ZRSR2

0.95	Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2

0.75	GO:0000398	mRNA splicing, via spliceosome
0.41	GO:0022618	ribonucleoprotein complex assembly

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.84	GO:0089701	U2AF
0.55	GO:0019013	viral nucleocapsid
0.53	GO:1990904	ribonucleoprotein complex
0.36	GO:0031981	nuclear lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q15697|ZN174_HUMAN
Zinc finger protein 174
Search

ZNF174

0.96	LOW QUALITY PROTEIN: zinc finger protein 174

0.67	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0006351	transcription, DNA-templated
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0051606	detection of stimulus
0.35	GO:0032501	multicellular organismal process
0.35	GO:0070895	negative regulation of transposon integration
0.33	GO:0042221	response to chemical
0.33	GO:0048856	anatomical structure development
0.32	GO:0009416	response to light stimulus

0.57	GO:0003700	DNA binding transcription factor activity
0.57	GO:0044212	transcription regulatory region DNA binding
0.56	GO:0042803	protein homodimerization activity
0.50	GO:0043565	sequence-specific DNA binding
0.50	GO:0046872	metal ion binding
0.35	GO:0004930	G-protein coupled receptor activity
0.35	GO:0003690	double-stranded DNA binding
0.35	GO:0004984	olfactory receptor activity
0.33	GO:0003682	chromatin binding
0.32	GO:0009881	photoreceptor activity

0.56	GO:0015629	actin cytoskeleton
0.56	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.52	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.45	GO:0005886	plasma membrane
0.33	GO:0001750	photoreceptor outer segment
0.30	GO:0031224	intrinsic component of membrane

sp|Q15699|ALX1_HUMAN
ALX homeobox protein 1
Search

ALX1

0.97	ALX homeobox protein 1

0.81	GO:0001755	neural crest cell migration
0.66	GO:0048704	embryonic skeletal system morphogenesis
0.59	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.59	GO:0030326	embryonic limb morphogenesis
0.57	GO:0060021	palate development
0.57	GO:0001843	neural tube closure
0.56	GO:0007389	pattern specification process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.63	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0046982	protein heterodimerization activity
0.51	GO:0003690	double-stranded DNA binding
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0003714	transcription corepressor activity

0.60	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.51	GO:0005794	Golgi apparatus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

sp|Q156A1|ATX8_HUMAN
Ataxin-8
Search

0.10

Ataxin-8

0.30	GO:0044464	cell part
0.30	GO:0043226	organelle

sp|Q15700|DLG2_HUMAN
Disks large homolog 2
Search

DLG2

0.93	Disks large like protein 2

0.83	GO:0019233	sensory perception of pain
0.82	GO:0010923	negative regulation of phosphatase activity
0.82	GO:0097120	receptor localization to synapse
0.81	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.81	GO:0043113	receptor clustering
0.78	GO:0007268	chemical synaptic transmission
0.74	GO:0046710	GDP metabolic process
0.71	GO:0046037	GMP metabolic process
0.70	GO:0007399	nervous system development
0.55	GO:0071695	anatomical structure maturation

0.84	GO:0035255	ionotropic glutamate receptor binding
0.75	GO:0019900	kinase binding
0.74	GO:0004385	guanylate kinase activity
0.57	GO:0030165	PDZ domain binding
0.56	GO:0019903	protein phosphatase binding
0.55	GO:0008022	protein C-terminus binding
0.51	GO:0046982	protein heterodimerization activity

0.85	GO:0044224	juxtaparanode region of axon
0.84	GO:0014069	postsynaptic density
0.80	GO:0008328	ionotropic glutamate receptor complex
0.79	GO:0045211	postsynaptic membrane
0.77	GO:0016323	basolateral plasma membrane
0.72	GO:0030054	cell junction
0.70	GO:0008076	voltage-gated potassium channel complex
0.54	GO:0043025	neuronal cell body
0.54	GO:0030425	dendrite
0.49	GO:0005829	cytosol

0.74

EC:2.7.4.8

GO:0004385

sp|Q15714|T22D1_HUMAN
TSC22 domain family protein 1
Search

TSC22D1

0.92	TSC22 domain family protein 1 isoform 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0008284	positive regulation of cell proliferation
0.37	GO:0043065	positive regulation of apoptotic process
0.37	GO:0043066	negative regulation of apoptotic process
0.32	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding
0.33	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q15717|ELAV1_HUMAN
ELAV-like protein 1
Search

ELAVL1

0.84	ELAV-like protein 1-B

0.55	GO:0070935	3'-UTR-mediated mRNA stabilization
0.55	GO:0060965	negative regulation of gene silencing by miRNA
0.53	GO:2000036	regulation of stem cell population maintenance
0.42	GO:0045766	positive regulation of angiogenesis
0.37	GO:0008298	intracellular mRNA localization
0.37	GO:0007369	gastrulation
0.36	GO:0051259	protein oligomerization
0.35	GO:0031440	regulation of mRNA 3'-end processing
0.34	GO:0000398	mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.50	GO:0019901	protein kinase binding
0.49	GO:0042803	protein homodimerization activity

0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.43	GO:1990904	ribonucleoprotein complex
0.36	GO:0005938	cell cortex
0.34	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

sp|Q15722|LT4R1_HUMAN
Leukotriene B4 receptor 1
Search

LTB4R

0.97	Leukotriene B4 receptor

0.85	GO:0061737	leukotriene signaling pathway
0.57	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.54	GO:0007218	neuropeptide signaling pathway
0.48	GO:0051546	keratinocyte migration
0.44	GO:0006954	inflammatory response
0.42	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.40	GO:0038178	complement component C5a signaling pathway
0.39	GO:0050679	positive regulation of epithelial cell proliferation
0.39	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.37	GO:0006935	chemotaxis

0.85	GO:0004974	leukotriene receptor activity
0.53	GO:0008528	G-protein coupled peptide receptor activity
0.40	GO:0004878	complement component C5a receptor activity
0.34	GO:0004989	octopamine receptor activity
0.34	GO:0005515	protein binding
0.33	GO:0042277	peptide binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0051378	serotonin binding
0.33	GO:0036094	small molecule binding
0.33	GO:0099589	serotonin receptor activity

0.48	GO:0005887	integral component of plasma membrane
0.42	GO:0098857	membrane microdomain
0.42	GO:0005654	nucleoplasm
0.39	GO:0009986	cell surface
0.36	GO:0009925	basal plasma membrane
0.35	GO:0045177	apical part of cell

sp|Q15723|ELF2_HUMAN
ETS-related transcription factor Elf-2
Search

ELF2

0.96	E74 like ETS transcription factor 2

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.43	GO:0030154	cell differentiation
0.37	GO:0051253	negative regulation of RNA metabolic process
0.37	GO:0010558	negative regulation of macromolecule biosynthetic process
0.37	GO:0031327	negative regulation of cellular biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part

sp|Q15726|KISS1_HUMAN
Metastasis-suppressor KiSS-1
Search

KISS1

0.97	Metastasis-suppressor KiSS-1

0.73	GO:0046697	decidualization
0.69	GO:0060112	generation of ovulation cycle rhythm
0.67	GO:0033686	positive regulation of luteinizing hormone secretion
0.66	GO:0060124	positive regulation of growth hormone secretion
0.65	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0050806	positive regulation of synaptic transmission
0.60	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.59	GO:0043410	positive regulation of MAPK cascade
0.58	GO:0008285	negative regulation of cell proliferation
0.47	GO:0016192	vesicle-mediated transport

0.71	GO:0031773	kisspeptin receptor binding
0.39	GO:0070001	aspartic-type peptidase activity
0.38	GO:0004175	endopeptidase activity

0.60	GO:0016324	apical plasma membrane
0.59	GO:0043025	neuronal cell body
0.57	GO:0043005	neuron projection
0.55	GO:0005615	extracellular space
0.41	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q15735|PI5PA_HUMAN
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
Search

INPP5J

0.96	Inositol polyphosphate-5-phosphatase Ja

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.72	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.68	GO:0010977	negative regulation of neuron projection development
0.39	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.39	GO:0090315	negative regulation of protein targeting to membrane
0.39	GO:0045719	negative regulation of glycogen biosynthetic process
0.39	GO:0043922	negative regulation by host of viral transcription
0.39	GO:0051497	negative regulation of stress fiber assembly
0.38	GO:0097178	ruffle assembly
0.38	GO:0071364	cellular response to epidermal growth factor stimulus

0.73	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
0.39	GO:0016312	inositol bisphosphate phosphatase activity
0.39	GO:0046030	inositol trisphosphate phosphatase activity
0.39	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
0.37	GO:0005000	vasopressin receptor activity

0.70	GO:0043198	dendritic shaft
0.68	GO:0001726	ruffle
0.68	GO:0030426	growth cone
0.48	GO:0005886	plasma membrane
0.43	GO:0005737	cytoplasm
0.36	GO:0031984	organelle subcompartment
0.36	GO:0012505	endomembrane system
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.39	EC:3.1.3	GO:0016312
0.39	KEGG:R04404	GO:0004439

sp|Q15738|NSDHL_HUMAN
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
Search

NSDHL

0.94	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0060716	labyrinthine layer blood vessel development
0.51	GO:0007224	smoothened signaling pathway
0.51	GO:0008203	cholesterol metabolic process
0.51	GO:0001942	hair follicle development
0.46	GO:0001878	response to yeast
0.38	GO:1902653	secondary alcohol biosynthetic process
0.31	GO:0006468	protein phosphorylation

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.42	GO:0103067	4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity
0.42	GO:0103066	4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity
0.42	GO:0047012	sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity
0.36	GO:0000252	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
0.31	GO:0004672	protein kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005811	lipid droplet
0.49	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.1.1.145

GO:0003854

sp|Q15742|NAB2_HUMAN
NGFI-A-binding protein 2
Search

NAB2

0.97	NGFI-A binding protein 2

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.70	GO:0001958	endochondral ossification
0.69	GO:0014037	Schwann cell differentiation
0.68	GO:0045682	regulation of epidermis development
0.67	GO:0042552	myelination
0.66	GO:0006359	regulation of transcription by RNA polymerase III
0.43	GO:1902949	positive regulation of tau-protein kinase activity
0.37	GO:0008283	cell proliferation
0.36	GO:0006351	transcription, DNA-templated

0.60	GO:0042802	identical protein binding
0.59	GO:0008134	transcription factor binding
0.38	GO:0003714	transcription corepressor activity

0.61

GO:0005634

nucleus

sp|Q15743|OGR1_HUMAN
Ovarian cancer G-protein coupled receptor 1
Search

GPR68

0.94	Ovarian cancer G-protein coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0009268	response to pH
0.51	GO:2001206	positive regulation of osteoclast development
0.51	GO:0045656	negative regulation of monocyte differentiation
0.50	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.46	GO:0072144	glomerular mesangial cell development
0.46	GO:0071214	cellular response to abiotic stimulus
0.45	GO:0060055	angiogenesis involved in wound healing
0.45	GO:0035025	positive regulation of Rho protein signal transduction
0.44	GO:0016525	negative regulation of angiogenesis

0.72

GO:0004930

G-protein coupled receptor activity

0.42

GO:0005887

integral component of plasma membrane

sp|Q15744|CEBPE_HUMAN
CCAAT/enhancer-binding protein epsilon
Search

CEBPE

0.97	CCAAT/enhancer-binding protein epsilon

0.80	GO:0042089	cytokine biosynthetic process
0.79	GO:0030225	macrophage differentiation
0.79	GO:0030851	granulocyte differentiation
0.74	GO:0006909	phagocytosis
0.70	GO:0042742	defense response to bacterium
0.68	GO:0006366	transcription by RNA polymerase II
0.67	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0071222	cellular response to lipopolysaccharide

0.73	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.72	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity

0.63

GO:0005654

nucleoplasm

sp|Q15746|MYLK_HUMAN
Myosin light chain kinase, smooth muscle
Search

MYLK

0.55	Myosin light chain kinase

0.63	GO:0060414	aorta smooth muscle tissue morphogenesis
0.63	GO:0006468	protein phosphorylation
0.62	GO:0032060	bleb assembly
0.60	GO:0071476	cellular hypotonic response
0.60	GO:0090303	positive regulation of wound healing
0.59	GO:0051928	positive regulation of calcium ion transport
0.57	GO:2000145	regulation of cell motility
0.57	GO:0051272	positive regulation of cellular component movement
0.56	GO:0040017	positive regulation of locomotion
0.48	GO:0006939	smooth muscle contraction

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005516	calmodulin binding
0.41	GO:0003779	actin binding
0.36	GO:0046872	metal ion binding
0.36	GO:0019899	enzyme binding

0.60	GO:0097610	cell surface furrow
0.59	GO:0097517	contractile actin filament bundle
0.59	GO:0042641	actomyosin
0.58	GO:0030027	lamellipodium
0.58	GO:0032155	cell division site part
0.43	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.40	GO:0070062	extracellular exosome
0.36	GO:0005911	cell-cell junction

sp|Q15750|TAB1_HUMAN
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Search

TAB1

0.96	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1

0.71	GO:0006470	protein dephosphorylation
0.59	GO:0060976	coronary vasculature development
0.59	GO:0035904	aorta development
0.59	GO:0000185	activation of MAPKKK activity
0.58	GO:0003279	cardiac septum development
0.57	GO:0030324	lung development
0.57	GO:0007179	transforming growth factor beta receptor signaling pathway
0.56	GO:0003007	heart morphogenesis
0.54	GO:0001701	in utero embryonic development
0.49	GO:0016310	phosphorylation

0.76	GO:0004722	protein serine/threonine phosphatase activity
0.57	GO:0019209	kinase activator activity
0.51	GO:0016301	kinase activity
0.42	GO:0048273	mitogen-activated protein kinase p38 binding
0.39	GO:0032403	protein complex binding
0.37	GO:0003830	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.55	GO:0016607	nuclear speck
0.49	GO:0005829	cytosol
0.36	GO:0043234	protein complex
0.35	GO:0010008	endosome membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.37

EC:2.4.1.144

GO:0003830

sp|Q15751|HERC1_HUMAN
Probable E3 ubiquitin-protein ligase HERC1
Search

HERC1

0.62	probable E3 ubiquitin-protein ligase HERC1

0.72	GO:0016567	protein ubiquitination
0.30	GO:0021697	cerebellar cortex formation
0.30	GO:0021692	cerebellar Purkinje cell layer morphogenesis
0.30	GO:0009892	negative regulation of metabolic process
0.30	GO:0030182	neuron differentiation
0.30	GO:0120036	plasma membrane bounded cell projection organization
0.30	GO:0021533	cell differentiation in hindbrain
0.30	GO:0048523	negative regulation of cellular process
0.30	GO:0065009	regulation of molecular function
0.30	GO:0050885	neuromuscular process controlling balance

0.72	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0016874	ligase activity
0.30	GO:0005515	protein binding
0.30	GO:0098772	molecular function regulator

0.30	GO:0016020	membrane
0.30	GO:0044464	cell part
0.30	GO:0043226	organelle

0.62	EC:6	GO:0016874
0.72	KEGG:R03876	GO:0004842

sp|Q15758|AAAT_HUMAN
Neutral amino acid transporter B(0)
Search

SLC1A5

0.45	Amino acid transporter

0.55	GO:0055085	transmembrane transport
0.50	GO:0015825	L-serine transport
0.49	GO:0034589	hydroxyproline transport
0.48	GO:0015811	L-cystine transport
0.47	GO:0015808	L-alanine transport
0.45	GO:0015826	threonine transport
0.45	GO:0050890	cognition
0.45	GO:0015824	proline transport
0.43	GO:0006821	chloride transport
0.42	GO:0036229	L-glutamine import

0.72	GO:0015293	symporter activity
0.50	GO:0015194	L-serine transmembrane transporter activity
0.49	GO:0034590	L-hydroxyproline transmembrane transporter activity
0.48	GO:0015184	L-cystine transmembrane transporter activity
0.48	GO:0015180	L-alanine transmembrane transporter activity
0.47	GO:0015195	L-threonine transmembrane transporter activity
0.45	GO:0015193	L-proline transmembrane transporter activity
0.44	GO:0005254	chloride channel activity
0.37	GO:0015186	L-glutamine transmembrane transporter activity
0.36	GO:0104005	hijacked molecular function

0.44	GO:0005882	intermediate filament
0.44	GO:0005813	centrosome
0.42	GO:0042470	melanosome
0.42	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.35	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q15759|MK11_HUMAN
Mitogen-activated protein kinase 11
Search

MAPK11

0.58	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.60	GO:2001184	positive regulation of interleukin-12 secretion
0.57	GO:0060043	regulation of cardiac muscle cell proliferation
0.55	GO:0098586	cellular response to virus
0.53	GO:0061117	negative regulation of heart growth
0.52	GO:0055026	negative regulation of cardiac muscle tissue development
0.50	GO:0010628	positive regulation of gene expression
0.49	GO:0045648	positive regulation of erythrocyte differentiation
0.49	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration
0.48	GO:0008285	negative regulation of cell proliferation

0.81	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0048273	mitogen-activated protein kinase p38 binding
0.48	GO:0051525	NFAT protein binding
0.46	GO:0019903	protein phosphatase binding
0.35	GO:0004708	MAP kinase kinase activity
0.34	GO:0008022	protein C-terminus binding

0.45	GO:0005622	intracellular
0.42	GO:0031974	membrane-enclosed lumen
0.41	GO:0043227	membrane-bounded organelle
0.39	GO:0044422	organelle part
0.39	GO:0043228	non-membrane-bounded organelle
0.35	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.33	GO:0012505	endomembrane system
0.30	GO:0044425	membrane part

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|Q15760|GPR19_HUMAN
Probable G-protein coupled receptor 19
Search

GPR19

0.97	G protein-coupled receptor 19

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0007631	feeding behavior
0.46	GO:0098916	anterograde trans-synaptic signaling
0.32	GO:1901652	response to peptide
0.32	GO:0032870	cellular response to hormone stimulus

0.72	GO:0004930	G-protein coupled receptor activity
0.40	GO:0001653	peptide receptor activity
0.32	GO:0030594	neurotransmitter receptor activity
0.32	GO:0042277	peptide binding

0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q15761|NPY5R_HUMAN
Neuropeptide Y receptor type 5
Search

NPY5R

0.97	Neuropeptide Y receptor type 5

0.80	GO:0007218	neuropeptide signaling pathway
0.70	GO:0003214	cardiac left ventricle morphogenesis
0.67	GO:0003151	outflow tract morphogenesis
0.63	GO:0007268	chemical synaptic transmission
0.57	GO:0007631	feeding behavior
0.53	GO:0008015	blood circulation
0.49	GO:0060112	generation of ovulation cycle rhythm
0.48	GO:0014050	negative regulation of glutamate secretion
0.48	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.48	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus

0.84	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0016494	C-X-C chemokine receptor activity
0.33	GO:0050254	rhodopsin kinase activity
0.32	GO:0042923	neuropeptide binding

0.61	GO:0043005	neuron projection
0.38	GO:0005886	plasma membrane
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.11.14

GO:0050254

sp|Q15762|CD226_HUMAN
CD226 antigen
Search

sp|Q15768|EFNB3_HUMAN
Ephrin-B3
Search

0.68	GO:0048013	ephrin receptor signaling pathway
0.62	GO:0031295	T cell costimulation
0.58	GO:0016198	axon choice point recognition
0.58	GO:0010977	negative regulation of neuron projection development
0.57	GO:0007628	adult walking behavior
0.57	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.55	GO:0050770	regulation of axonogenesis
0.44	GO:0048513	animal organ development
0.44	GO:0001667	ameboidal-type cell migration
0.43	GO:0009888	tissue development

0.70	GO:0046875	ephrin receptor binding
0.37	GO:0001618	virus receptor activity
0.37	GO:0005005	transmembrane-ephrin receptor activity
0.36	GO:0003777	microtubule motor activity
0.34	GO:0016887	ATPase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008144	drug binding

0.45	GO:0005886	plasma membrane
0.40	GO:0098857	membrane microdomain
0.36	GO:0005634	nucleus
0.35	GO:0005925	focal adhesion
0.35	GO:0030286	dynein complex
0.34	GO:0005737	cytoplasm
0.33	GO:0070062	extracellular exosome
0.33	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

sp|Q15771|RAB30_HUMAN
Ras-related protein Rab-30
Search

RAB30

0.90	Putative rab subfamily protein of small gtpase

0.54	GO:0007030	Golgi organization
0.44	GO:0046528	imaginal disc fusion
0.44	GO:0007390	germ-band shortening
0.43	GO:0008258	head involution
0.43	GO:0007391	dorsal closure
0.34	GO:0032482	Rab protein signal transduction
0.33	GO:0016192	vesicle-mediated transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.32	GO:0005515	protein binding

0.57	GO:0005802	trans-Golgi network
0.54	GO:0005801	cis-Golgi network
0.53	GO:0031985	Golgi cisterna
0.40	GO:0045202	synapse
0.40	GO:0005768	endosome
0.34	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|Q15772|SPEG_HUMAN
Striated muscle preferentially expressed protein kinase
Search

SPEG

0.85	striated muscle preferentially expressed protein kinase

0.63	GO:0006468	protein phosphorylation
0.37	GO:0061061	muscle structure development
0.36	GO:0048513	animal organ development
0.33	GO:0030154	cell differentiation
0.32	GO:0001701	in utero embryonic development
0.32	GO:0060541	respiratory system development
0.32	GO:0014706	striated muscle tissue development
0.32	GO:0072358	cardiovascular system development
0.32	GO:0008285	negative regulation of cell proliferation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0005515	protein binding

0.37	GO:0030018	Z disc
0.34	GO:0005634	nucleus

0.70

GO:0004674

sp|Q15773|MLF2_HUMAN
Myeloid leukemia factor 2
Search

MLF2

0.97	Myelodysplasia-myeloid leukemia factor 2

0.65	GO:0006952	defense response
0.38	GO:0007050	cell cycle arrest

0.40	GO:0005515	protein binding
0.37	GO:0003950	NAD+ ADP-ribosyltransferase activity

0.56	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.37

GO:0003950

sp|Q15776|ZKSC8_HUMAN
Zinc finger protein with KRAB and SCAN domains 8
Search

0.71	zinc finger protein with KRAB and SCAN domains 4

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0006351	transcription, DNA-templated
0.41	GO:0015074	DNA integration
0.36	GO:2000773	negative regulation of cellular senescence
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0007040	lysosome organization
0.35	GO:0007219	Notch signaling pathway
0.35	GO:0010507	negative regulation of autophagy

0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.37	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.35	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome

sp|Q15777|MPPD2_HUMAN
Metallophosphoesterase MPPED2
Search

MPPED2

0.97	Metallophosphoesterase domain containing 2

0.37	GO:0072015	glomerular visceral epithelial cell development
0.34	GO:0007399	nervous system development

0.50	GO:0016787	hydrolase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.30

GO:0016020

membrane

0.50

GO:0016787

sp|Q15782|CH3L2_HUMAN
Chitinase-3-like protein 2
Search

0.46	Acidic mammalian chitinase

0.64	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.52	GO:0045766	positive regulation of angiogenesis
0.51	GO:1901072	glucosamine-containing compound catabolic process
0.48	GO:0006026	aminoglycan catabolic process
0.47	GO:0042737	drug catabolic process
0.45	GO:0072606	interleukin-8 secretion
0.44	GO:0070741	response to interleukin-6
0.44	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.44	GO:0007250	activation of NF-kappaB-inducing kinase activity

0.77	GO:0008061	chitin binding
0.58	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0030246	carbohydrate binding

0.64	GO:0005576	extracellular region
0.40	GO:0005783	endoplasmic reticulum
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005764	lysosome
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.30	GO:0016020	membrane

0.58

GO:0004553

sp|Q15784|NDF2_HUMAN
Neurogenic differentiation factor 2
Search

NEUROD2

0.90	Neurogenic differentiation factor

0.77	GO:0090128	regulation of synapse maturation
0.74	GO:0048699	generation of neurons
0.72	GO:0060284	regulation of cell development
0.62	GO:0048468	cell development
0.61	GO:0021549	cerebellum development
0.60	GO:0051091	positive regulation of DNA binding transcription factor activity
0.59	GO:0051962	positive regulation of nervous system development
0.58	GO:0031915	positive regulation of synaptic plasticity
0.58	GO:0045597	positive regulation of cell differentiation
0.57	GO:0071257	cellular response to electrical stimulus

0.68	GO:0046983	protein dimerization activity
0.63	GO:0070888	E-box binding
0.60	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0003712	transcription cofactor activity
0.50	GO:0001102	RNA polymerase II activating transcription factor binding
0.50	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.49	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0003682	chromatin binding
0.33	GO:0005509	calcium ion binding

0.58	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen

sp|Q15785|TOM34_HUMAN
Mitochondrial import receptor subunit TOM34
Search

TOMM34

0.92	Translocase of outer mitochondrial membrane 34

0.74	GO:0006626	protein targeting to mitochondrion
0.41	GO:0070286	axonemal dynein complex assembly
0.39	GO:0007338	single fertilization

0.73	GO:0031072	heat shock protein binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016787	hydrolase activity

0.73	GO:0005741	mitochondrial outer membrane
0.68	GO:0005829	cytosol
0.66	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0016787

sp|Q15788|NCOA1_HUMAN
Nuclear receptor coactivator 1
Search

NCOA1

0.96	LOW QUALITY PROTEIN: nuclear receptor coactivator 1

0.62	GO:1904017	cellular response to Thyroglobulin triiodothyronine
0.61	GO:0000435	positive regulation of transcription from RNA polymerase II promoter by galactose
0.61	GO:0002155	regulation of thyroid hormone mediated signaling pathway
0.58	GO:0060713	labyrinthine layer morphogenesis
0.57	GO:2001038	regulation of cellular response to drug
0.57	GO:0043967	histone H4 acetylation
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0045666	positive regulation of neuron differentiation
0.54	GO:0043065	positive regulation of apoptotic process
0.47	GO:0032870	cellular response to hormone stimulus

0.85	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.82	GO:0035257	nuclear hormone receptor binding
0.66	GO:0046983	protein dimerization activity
0.62	GO:0017162	aryl hydrocarbon receptor binding
0.59	GO:0047485	protein N-terminus binding
0.53	GO:0003682	chromatin binding
0.52	GO:0019899	enzyme binding
0.42	GO:0003677	DNA binding
0.39	GO:0004402	histone acetyltransferase activity
0.39	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.52	GO:0000785	chromatin
0.50	GO:0070013	intracellular organelle lumen
0.50	GO:0005829	cytosol
0.46	GO:0043234	protein complex
0.43	GO:0005886	plasma membrane
0.38	GO:0043005	neuron projection
0.30	GO:0044425	membrane part

0.39

GO:0004402

sp|Q15796|SMAD2_HUMAN
Mothers against decapentaplegic homolog 2
Search

SMAD2

0.64	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.59	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
0.59	GO:0007352	zygotic specification of dorsal/ventral axis
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0007182	common-partner SMAD protein phosphorylation
0.58	GO:0038092	nodal signaling pathway
0.58	GO:0007183	SMAD protein complex assembly
0.57	GO:0048340	paraxial mesoderm morphogenesis
0.57	GO:0070723	response to cholesterol
0.57	GO:0048617	embryonic foregut morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.57	GO:0070410	co-SMAD binding
0.57	GO:0070878	primary miRNA binding
0.57	GO:0070411	I-SMAD binding
0.57	GO:0034713	type I transforming growth factor beta receptor binding
0.57	GO:0070412	R-SMAD binding
0.56	GO:0097718	disordered domain specific binding
0.55	GO:0033613	activating transcription factor binding
0.55	GO:0003677	DNA binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.57	GO:0071141	SMAD protein complex
0.49	GO:0000785	chromatin
0.49	GO:0005737	cytoplasm
0.47	GO:0070013	intracellular organelle lumen
0.35	GO:0097708	intracellular vesicle
0.30	GO:0016020	membrane

sp|Q15797|SMAD1_HUMAN
Mothers against decapentaplegic homolog 1
Search

SMAD1

0.64	Mothers against decapentaplegic homolog

0.82	GO:0007179	transforming growth factor beta receptor signaling pathway
0.59	GO:0002051	osteoblast fate commitment
0.59	GO:0030509	BMP signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0045669	positive regulation of osteoblast differentiation
0.56	GO:0060395	SMAD protein signal transduction
0.56	GO:0007183	SMAD protein complex assembly
0.56	GO:0001657	ureteric bud development
0.56	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
0.55	GO:0001710	mesodermal cell fate commitment

0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0017151	DEAD/H-box RNA helicase binding
0.56	GO:0070410	co-SMAD binding
0.56	GO:0070878	primary miRNA binding
0.56	GO:0070411	I-SMAD binding
0.54	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0019901	protein kinase binding
0.50	GO:0046982	protein heterodimerization activity
0.49	GO:0042803	protein homodimerization activity

0.74	GO:0005667	transcription factor complex
0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.46	GO:0012505	endomembrane system
0.44	GO:0019866	organelle inner membrane
0.38	GO:0070013	intracellular organelle lumen
0.35	GO:0071141	SMAD protein complex
0.34	GO:0097708	intracellular vesicle
0.30	GO:0016021	integral component of membrane

sp|Q15800|MSMO1_HUMAN
Methylsterol monooxygenase 1
Search

MSMO1

0.92	Methylsterol monooxygenase 1

0.65	GO:0008610	lipid biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0016125	sterol metabolic process
0.48	GO:1901617	organic hydroxy compound biosynthetic process
0.40	GO:1901362	organic cyclic compound biosynthetic process
0.35	GO:1902652	secondary alcohol metabolic process
0.34	GO:0006631	fatty acid metabolic process
0.34	GO:0044283	small molecule biosynthetic process
0.33	GO:0044107	cellular alcohol metabolic process
0.33	GO:0016128	phytosteroid metabolic process

0.62	GO:0005506	iron ion binding
0.57	GO:0004497	monooxygenase activity
0.45	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0004318	enoyl-[acyl-carrier-protein] reductase (NADH) activity

0.47	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005835	fatty acid synthase complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.45

GO:0016705

sp|Q15811|ITSN1_HUMAN
Intersectin-1
Search

ITSN1

0.92	Intersectin-1 isoform ITSN-l

0.72	GO:0035023	regulation of Rho protein signal transduction
0.62	GO:0065009	regulation of molecular function
0.59	GO:0035556	intracellular signal transduction
0.51	GO:0051897	positive regulation of protein kinase B signaling
0.51	GO:0043524	negative regulation of neuron apoptotic process
0.48	GO:0042327	positive regulation of phosphorylation
0.36	GO:0006897	endocytosis
0.36	GO:0036465	synaptic vesicle recycling
0.36	GO:2001288	positive regulation of caveolin-mediated endocytosis
0.35	GO:0048013	ephrin receptor signaling pathway

0.72	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.69	GO:0005509	calcium ion binding
0.54	GO:0070064	proline-rich region binding
0.51	GO:0032947	protein complex scaffold activity
0.50	GO:0019209	kinase activator activity

0.51	GO:0005905	clathrin-coated pit
0.50	GO:0030027	lamellipodium
0.49	GO:0030139	endocytic vesicle
0.41	GO:0005886	plasma membrane
0.37	GO:0043005	neuron projection
0.37	GO:0045202	synapse
0.37	GO:0030054	cell junction
0.35	GO:0005829	cytosol
0.34	GO:0043025	neuronal cell body
0.34	GO:0120038	plasma membrane bounded cell projection part

sp|Q15813|TBCE_HUMAN
Tubulin-specific chaperone E
Search

TBCE

0.89	Tubulin-specific chaperone E

0.85	GO:0048936	peripheral nervous system neuron axonogenesis
0.85	GO:0014889	muscle atrophy
0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.81	GO:0007052	mitotic spindle organization
0.80	GO:0008344	adult locomotory behavior
0.76	GO:0048589	developmental growth
0.75	GO:0009791	post-embryonic development
0.41	GO:0007021	tubulin complex assembly
0.34	GO:0098655	cation transmembrane transport
0.33	GO:0006518	peptide metabolic process

0.41	GO:0051087	chaperone binding
0.38	GO:0051082	unfolded protein binding
0.34	GO:0008324	cation transmembrane transporter activity
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0008080	N-acetyltransferase activity

0.50	GO:0005856	cytoskeleton
0.40	GO:0005737	cytoplasm
0.40	GO:0099512	supramolecular fiber
0.36	GO:0044446	intracellular organelle part
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.33

GO:0008080

sp|Q15814|TBCC_HUMAN
Tubulin-specific chaperone C
Search

TBCC

0.91	Tubulin-specific chaperone C

0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.51	GO:0007021	tubulin complex assembly
0.34	GO:0007601	visual perception
0.34	GO:0000226	microtubule cytoskeleton organization
0.33	GO:0043547	positive regulation of GTPase activity

0.73	GO:0015631	tubulin binding
0.60	GO:0032550	purine ribonucleoside binding
0.59	GO:0032561	guanyl ribonucleotide binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0003924	GTPase activity
0.35	GO:0051087	chaperone binding
0.33	GO:0005096	GTPase activator activity

0.58	GO:0032391	photoreceptor connecting cilium
0.48	GO:0005829	cytosol
0.35	GO:0005874	microtubule
0.33	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|Q15818|NPTX1_HUMAN
Neuronal pentraxin-1
Search

NPTX1

0.97	Neuronal pentraxin I

0.81	GO:0060385	axonogenesis involved in innervation
0.55	GO:0008306	associative learning
0.40	GO:0035865	cellular response to potassium ion
0.40	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.40	GO:0007268	chemical synaptic transmission
0.39	GO:0071333	cellular response to glucose stimulus
0.38	GO:0007417	central nervous system development
0.38	GO:0006839	mitochondrial transport
0.37	GO:0048168	regulation of neuronal synaptic plasticity
0.37	GO:0042752	regulation of circadian rhythm

0.41	GO:0046872	metal ion binding
0.35	GO:0030246	carbohydrate binding

0.43	GO:0030133	transport vesicle
0.43	GO:0005576	extracellular region
0.38	GO:0043005	neuron projection
0.35	GO:0005739	mitochondrion
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q15819|UB2V2_HUMAN
Ubiquitin-conjugating enzyme E2 variant 2
Search

UBE2V2

0.58	Ubiquitin-conjugating enzyme

0.75	GO:0006301	postreplication repair
0.72	GO:0070534	protein K63-linked ubiquitination
0.68	GO:0000729	DNA double-strand break processing
0.52	GO:0048584	positive regulation of response to stimulus
0.50	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.49	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.49	GO:0048522	positive regulation of cellular process
0.48	GO:0043524	negative regulation of neuron apoptotic process
0.48	GO:0051963	regulation of synapse assembly
0.48	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process

0.70	GO:0061631	ubiquitin conjugating enzyme activity
0.61	GO:0031625	ubiquitin protein ligase binding
0.59	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0003678	DNA helicase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0031371	ubiquitin conjugating enzyme complex
0.62	GO:0005654	nucleoplasm
0.48	GO:0000151	ubiquitin ligase complex
0.43	GO:0005737	cytoplasm
0.41	GO:0070062	extracellular exosome
0.37	GO:0042555	MCM complex
0.30	GO:0016020	membrane

sp|Q15822|ACHA2_HUMAN
Neuronal acetylcholine receptor subunit alpha-2
Search

CHRNA2

0.93	Nicotinic acetylcholine receptor alpha 2 subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.57	GO:0035094	response to nicotine
0.57	GO:0007271	synaptic transmission, cholinergic
0.53	GO:0007274	neuromuscular synaptic transmission
0.48	GO:0060080	inhibitory postsynaptic potential
0.47	GO:0014059	regulation of dopamine secretion
0.47	GO:0035640	exploration behavior
0.47	GO:0007585	respiratory gaseous exchange
0.47	GO:0051899	membrane depolarization

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.55	GO:0042166	acetylcholine binding
0.34	GO:0005515	protein binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.63	GO:0005892	acetylcholine-gated channel complex
0.45	GO:0009897	external side of plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite

sp|Q15825|ACHA6_HUMAN
Neuronal acetylcholine receptor subunit alpha-6
Search

CHRNA6

0.88	Neuronal acetylcholine receptor subunit alpha-6

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.58	GO:0035094	response to nicotine
0.57	GO:0007274	neuromuscular synaptic transmission
0.53	GO:0060073	micturition
0.50	GO:0007271	synaptic transmission, cholinergic
0.49	GO:0030534	adult behavior
0.46	GO:0007399	nervous system development
0.46	GO:0051952	regulation of amine transport
0.45	GO:2001023	regulation of response to drug

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.50	GO:0042166	acetylcholine binding
0.43	GO:0022850	serotonin-gated cation-selective channel activity
0.36	GO:0005515	protein binding
0.33	GO:0051537	2 iron, 2 sulfur cluster binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.58	GO:0005892	acetylcholine-gated channel complex
0.34	GO:0044853	plasma membrane raft
0.34	GO:0014069	postsynaptic density
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite

sp|Q15828|CYTM_HUMAN
Cystatin-M
Search

CST6

0.69	Cystatin-M

0.76	GO:0010951	negative regulation of endopeptidase activity
0.65	GO:0008544	epidermis development
0.52	GO:2000116	regulation of cysteine-type endopeptidase activity
0.37	GO:0009653	anatomical structure morphogenesis

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.53	GO:0002020	protease binding
0.34	GO:0003677	DNA binding

0.69	GO:0001533	cornified envelope
0.48	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q15831|STK11_HUMAN
Serine/threonine-protein kinase STK11
Search

STK11

0.95	Serine/threonine-protein kinase 11

0.63	GO:0006468	protein phosphorylation
0.59	GO:0036399	TCR signalosome assembly
0.58	GO:0071493	cellular response to UV-B
0.57	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development
0.57	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.57	GO:0043276	anoikis
0.57	GO:0045059	positive thymic T cell selection
0.57	GO:0097484	dendrite extension
0.57	GO:0048871	multicellular organismal homeostasis
0.57	GO:0042593	glucose homeostasis

0.68	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0030275	LRR domain binding
0.56	GO:0030295	protein kinase activator activity
0.55	GO:0002039	p53 binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0000287	magnesium ion binding
0.34	GO:0019901	protein kinase binding

0.58	GO:0036398	TCR signalosome
0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.68

GO:0004674

sp|Q15833|STXB2_HUMAN
Syntaxin-binding protein 2
Search

STXBP2

0.90	Syntaxin-binding protein 2

0.80	GO:0006904	vesicle docking involved in exocytosis
0.56	GO:0043312	neutrophil degranulation
0.55	GO:0071346	cellular response to interferon-gamma
0.55	GO:0001909	leukocyte mediated cytotoxicity
0.45	GO:0002576	platelet degranulation
0.44	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.44	GO:0007412	axon target recognition
0.44	GO:0099011	neuronal dense core vesicle exocytosis
0.43	GO:0016188	synaptic vesicle maturation
0.43	GO:1903305	regulation of regulated secretory pathway

0.59	GO:0030348	syntaxin-3 binding
0.57	GO:0017075	syntaxin-1 binding
0.35	GO:0043274	phospholipase binding
0.35	GO:0098772	molecular function regulator
0.34	GO:0047485	protein N-terminus binding
0.34	GO:0005102	receptor binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0042802	identical protein binding
0.32	GO:0003723	RNA binding

0.57	GO:0044194	cytolytic granule
0.57	GO:0070820	tertiary granule
0.56	GO:0042582	azurophil granule
0.56	GO:0042581	specific granule
0.55	GO:0042589	zymogen granule membrane
0.54	GO:0045335	phagocytic vesicle
0.53	GO:0031201	SNARE complex
0.51	GO:0098590	plasma membrane region
0.51	GO:0045177	apical part of cell
0.50	GO:0005829	cytosol

sp|Q15834|CC85B_HUMAN
Coiled-coil domain-containing protein 85B
Search

CCDC85B

0.96	Delta-interacting protein A

0.74	GO:0045599	negative regulation of fat cell differentiation
0.71	GO:0030308	negative regulation of cell growth
0.62	GO:0045892	negative regulation of transcription, DNA-templated
0.56	GO:0001843	neural tube closure
0.49	GO:0016246	RNA interference
0.41	GO:0030154	cell differentiation
0.38	GO:0006351	transcription, DNA-templated
0.33	GO:0055085	transmembrane transport
0.33	GO:0016310	phosphorylation

0.39	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0022857	transmembrane transporter activity
0.33	GO:0016301	kinase activity

0.67	GO:0005813	centrosome
0.54	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q15835|RK_HUMAN
Rhodopsin kinase
Search

GRK1

0.69	G protein-coupled receptor kinase

0.77	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.67	GO:0007601	visual perception
0.63	GO:0006468	protein phosphorylation
0.60	GO:0007165	signal transduction
0.43	GO:0048601	oocyte morphogenesis
0.42	GO:0009886	post-embryonic animal morphogenesis
0.42	GO:0003384	apical constriction involved in gastrulation
0.42	GO:0008592	regulation of Toll signaling pathway
0.41	GO:0043950	positive regulation of cAMP-mediated signaling
0.41	GO:0002805	regulation of antimicrobial peptide biosynthetic process

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.80	GO:0050254	rhodopsin kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0047696	beta-adrenergic receptor kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0008020	G-protein coupled photoreceptor activity

0.41	GO:0001750	photoreceptor outer segment
0.38	GO:0060170	ciliary membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.7.11.16

GO:0004703

sp|Q15836|VAMP3_HUMAN
Vesicle-associated membrane protein 3
Search

VAMP3

0.96	Sodium channel epithelial 1 alpha subunit

0.69	GO:0016192	vesicle-mediated transport
0.59	GO:0061951	establishment of protein localization to plasma membrane
0.57	GO:0090174	organelle membrane fusion
0.56	GO:1903530	regulation of secretion by cell
0.56	GO:0001921	positive regulation of receptor recycling
0.55	GO:0016050	vesicle organization
0.54	GO:0034446	substrate adhesion-dependent cell spreading
0.53	GO:0071346	cellular response to interferon-gamma
0.52	GO:0032940	secretion by cell
0.52	GO:0051048	negative regulation of secretion

0.54	GO:0000149	SNARE binding
0.49	GO:0005484	SNAP receptor activity
0.46	GO:0005516	calmodulin binding
0.45	GO:0005543	phospholipid binding
0.39	GO:0008022	protein C-terminus binding
0.39	GO:0048306	calcium-dependent protein binding
0.38	GO:0044325	ion channel binding
0.38	GO:0017022	myosin binding
0.36	GO:0032403	protein complex binding
0.36	GO:0042802	identical protein binding

0.61	GO:0031201	SNARE complex
0.57	GO:0030141	secretory granule
0.56	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0055037	recycling endosome
0.52	GO:0045335	phagocytic vesicle
0.52	GO:0030136	clathrin-coated vesicle
0.49	GO:0009986	cell surface
0.49	GO:0030672	synaptic vesicle membrane
0.47	GO:0005829	cytosol
0.47	GO:0005802	trans-Golgi network

0.33

EC:1.13.11

GO:0016702

sp|Q15842|KCNJ8_HUMAN
ATP-sensitive inward rectifier potassium channel 8
Search

KCNJ8

0.97	ATP-sensitive inward rectifier potassium channel 8

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.61	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.60	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.60	GO:0086005	ventricular cardiac muscle cell action potential
0.58	GO:0014070	response to organic cyclic compound
0.57	GO:0099587	inorganic ion import across plasma membrane
0.57	GO:1901698	response to nitrogen compound
0.56	GO:0032496	response to lipopolysaccharide

0.86	GO:0015272	ATP-activated inward rectifier potassium channel activity
0.61	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
0.50	GO:0030506	ankyrin binding
0.48	GO:0044325	ion channel binding
0.43	GO:0017098	sulfonylurea receptor binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.37	GO:0008022	protein C-terminus binding

0.55	GO:0030016	myofibril
0.54	GO:0008282	inward rectifying potassium channel
0.47	GO:0042383	sarcolemma
0.39	GO:0070852	cell body fiber
0.38	GO:0030673	axolemma
0.38	GO:0014704	intercalated disc
0.37	GO:0001669	acrosomal vesicle
0.37	GO:0043209	myelin sheath
0.37	GO:0005739	mitochondrion
0.37	GO:0043025	neuronal cell body

sp|Q15843|NEDD8_HUMAN
NEDD8
Search

NEDD8

0.75	Neural precursor cell expressed, developmentally down-regulated 8

0.77	GO:0045116	protein neddylation
0.61	GO:0036099	female germ-line stem cell population maintenance
0.60	GO:0030431	sleep
0.59	GO:2000736	regulation of stem cell differentiation
0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0008589	regulation of smoothened signaling pathway
0.57	GO:0051438	regulation of ubiquitin-protein transferase activity
0.56	GO:0008283	cell proliferation
0.55	GO:0031647	regulation of protein stability
0.55	GO:0008104	protein localization

0.65	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0016791	phosphatase activity
0.39	GO:0031386	protein tag
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0004519	endonuclease activity

0.58	GO:0005654	nucleoplasm
0.57	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome

0.45

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q15846|CLUL1_HUMAN
Clusterin-like protein 1
Search

CLUL1

0.94

Clusterin

sp|Q15847|ADIRF_HUMAN
Adipogenesis regulatory factor
Search

ADIRF

0.97	Adipogenesis regulatory factor

0.85	GO:0045600	positive regulation of fat cell differentiation
0.78	GO:0072719	cellular response to cisplatin
0.71	GO:2001023	regulation of response to drug
0.68	GO:0071478	cellular response to radiation
0.64	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated

0.61	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.41	GO:0070062	extracellular exosome

sp|Q15848|ADIPO_HUMAN
Adiponectin
Search

ADIPOQ

0.97	Adiponectin

0.65	GO:2000534	positive regulation of renal albumin absorption
0.64	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process
0.63	GO:2000481	positive regulation of cAMP-dependent protein kinase activity
0.63	GO:1904753	negative regulation of vascular associated smooth muscle cell migration
0.63	GO:0045650	negative regulation of macrophage differentiation
0.62	GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development
0.62	GO:2000590	negative regulation of metanephric mesenchymal cell migration
0.62	GO:0033034	positive regulation of myeloid cell apoptotic process
0.62	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.62	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway

0.60	GO:0033691	sialic acid binding
0.56	GO:0005179	hormone activity
0.51	GO:0042803	protein homodimerization activity
0.35	GO:0005125	cytokine activity

0.78	GO:0005581	collagen trimer
0.66	GO:0005576	extracellular region
0.54	GO:0009986	cell surface
0.50	GO:0005783	endoplasmic reticulum
0.44	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0071944	cell periphery
0.36	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q15849|UT2_HUMAN
Urea transporter 2
Search

0.10	Urea transporter 2

0.84	GO:0071918	urea transmembrane transport
0.37	GO:0006833	water transport

0.84	GO:0015204	urea transmembrane transporter activity
0.37	GO:0005372	water transmembrane transporter activity
0.35	GO:0022838	substrate-specific channel activity
0.30	GO:0050839	cell adhesion molecule binding

0.52	GO:0005886	plasma membrane
0.37	GO:0045177	apical part of cell
0.35	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

sp|Q15853|USF2_HUMAN
Upstream stimulatory factor 2
Search

USF2

0.93	Upstream transcription factor 2, c-fos interacting

0.60	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose
0.56	GO:0007595	lactation
0.54	GO:0055088	lipid homeostasis
0.51	GO:0006366	transcription by RNA polymerase II
0.38	GO:0019086	late viral transcription
0.34	GO:0032869	cellular response to insulin stimulus
0.34	GO:0006265	DNA topological change
0.34	GO:0001666	response to hypoxia
0.34	GO:0009411	response to UV

0.67	GO:0046983	protein dimerization activity
0.58	GO:0043425	bHLH transcription factor binding
0.56	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.51	GO:0042802	identical protein binding
0.46	GO:0043565	sequence-specific DNA binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0061505	DNA topoisomerase II activity
0.34	GO:0042826	histone deacetylase binding
0.34	GO:0008094	DNA-dependent ATPase activity

0.49	GO:0005654	nucleoplasm
0.34	GO:0016589	NURF complex
0.34	GO:0034708	methyltransferase complex
0.34	GO:0005667	transcription factor complex

sp|Q15858|SCN9A_HUMAN
Sodium channel protein type 9 subunit alpha
Search

0.66	Sodium voltage-gated channel alpha subunit 9

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0035725	sodium ion transmembrane transport
0.71	GO:0048266	behavioral response to pain
0.65	GO:0006954	inflammatory response
0.62	GO:0019233	sensory perception of pain
0.58	GO:0019228	neuronal action potential
0.55	GO:0086010	membrane depolarization during action potential
0.53	GO:0009791	post-embryonic development
0.48	GO:0098870	action potential propagation
0.48	GO:0009636	response to toxic substance

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.72	GO:0022839	ion gated channel activity
0.72	GO:0008381	mechanosensitive ion channel activity
0.39	GO:0031402	sodium ion binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.48	GO:0043194	axon initial segment
0.48	GO:0033268	node of Ranvier
0.47	GO:0030315	T-tubule
0.47	GO:0014704	intercalated disc
0.46	GO:0030018	Z disc
0.45	GO:0043025	neuronal cell body
0.44	GO:0016604	nuclear body
0.35	GO:0033270	paranode region of axon

sp|Q15878|CAC1E_HUMAN
Voltage-dependent R-type calcium channel subunit alpha-1E
Search

CACNA1E

0.89	Voltage-dependent R-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.51	GO:0086010	membrane depolarization during action potential
0.40	GO:0050796	regulation of insulin secretion
0.40	GO:0090273	regulation of somatostatin secretion
0.39	GO:0048266	behavioral response to pain
0.38	GO:0001662	behavioral fear response
0.38	GO:0008542	visual learning
0.38	GO:0019233	sensory perception of pain
0.38	GO:0019226	transmission of nerve impulse

0.82	GO:0005245	voltage-gated calcium channel activity
0.64	GO:0005509	calcium ion binding
0.38	GO:0047485	protein N-terminus binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.36	GO:0043204	perikaryon

sp|Q15884|F1892_HUMAN
Protein FAM189A2
Search

sp|Q15904|VAS1_HUMAN
V-type proton ATPase subunit S1
Search

ATP6AP1

0.92	ATPase H+ transporting accessory protein 1

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.72	GO:2001206	positive regulation of osteoclast development
0.70	GO:0046852	positive regulation of bone remodeling
0.70	GO:0036295	cellular response to increased oxygen levels
0.69	GO:0045124	regulation of bone resorption
0.68	GO:0045669	positive regulation of osteoblast differentiation
0.67	GO:0045851	pH reduction
0.67	GO:0045921	positive regulation of exocytosis
0.66	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.65	GO:0032846	positive regulation of homeostatic process

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.64	GO:0017137	Rab GTPase binding
0.39	GO:0005093	Rab GDP-dissociation inhibitor activity

0.81	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.38	GO:0005886	plasma membrane
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q15906|VPS72_HUMAN
Vacuolar protein sorting-associated protein 72 homolog
Search

VPS72

0.96	Vacuolar protein sorting-associated protein 72

0.84	GO:0043486	histone exchange
0.58	GO:0035019	somatic stem cell population maintenance
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0016569	covalent chromatin modification
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0048519	negative regulation of biological process
0.34	GO:0018393	internal peptidyl-lysine acetylation
0.33	GO:0030834	regulation of actin filament depolymerization

0.54	GO:0042393	histone binding
0.35	GO:0003677	DNA binding
0.34	GO:0004402	histone acetyltransferase activity
0.33	GO:0005523	tropomyosin binding
0.33	GO:0004017	adenylate kinase activity
0.33	GO:0051015	actin filament binding
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.45	GO:0043234	protein complex
0.44	GO:0044446	intracellular organelle part
0.33	GO:0031248	protein acetyltransferase complex

0.34

GO:0004402

sp|Q15907|RB11B_HUMAN
Ras-related protein Rab-11B
Search

0.45	GTP-binding protein YPT3

0.65	GO:0032402	melanosome transport
0.57	GO:0006887	exocytosis
0.57	GO:0060627	regulation of vesicle-mediated transport
0.56	GO:0010796	regulation of multivesicular body size
0.56	GO:0097734	extracellular exosome biogenesis
0.56	GO:0030953	astral microtubule organization
0.55	GO:0036258	multivesicular body assembly
0.55	GO:0045773	positive regulation of axon extension
0.54	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.54	GO:0072657	protein localization to membrane

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.63	GO:0031489	myosin V binding
0.50	GO:0019003	GDP binding
0.49	GO:0008017	microtubule binding
0.48	GO:0045296	cadherin binding
0.34	GO:0019905	syntaxin binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0016874	ligase activity

0.61	GO:0055037	recycling endosome
0.60	GO:0045335	phagocytic vesicle
0.54	GO:0005771	multivesicular body
0.54	GO:0032154	cleavage furrow
0.54	GO:0005828	kinetochore microtubule
0.52	GO:0070062	extracellular exosome
0.52	GO:0030424	axon
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005802	trans-Golgi network
0.51	GO:0000922	spindle pole

0.33

GO:0016874

sp|Q15910|EZH2_HUMAN
Histone-lysine N-methyltransferase EZH2
Search

EZH2

0.95	Enhancer of zeste 2 polycomb repressive complex 2 subunit

0.77	GO:0034968	histone lysine methylation
0.57	GO:1904772	response to tetrachloromethane
0.57	GO:0036333	hepatocyte homeostasis
0.57	GO:0035983	response to trichostatin A
0.56	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
0.56	GO:0070314	G1 to G0 transition
0.55	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.55	GO:0045605	negative regulation of epidermal cell differentiation
0.55	GO:0097421	liver regeneration
0.55	GO:0071236	cellular response to antibiotic

0.78	GO:0018024	histone-lysine N-methyltransferase activity
0.55	GO:1990841	promoter-specific chromatin binding
0.55	GO:0070878	primary miRNA binding
0.54	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.52	GO:0031490	chromatin DNA binding
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0043021	ribonucleoprotein complex binding
0.35	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.55	GO:0035098	ESC/E(Z) complex
0.54	GO:0045120	pronucleus
0.49	GO:0000790	nuclear chromatin
0.33	GO:0005737	cytoplasm

0.78

EC:2.1.1.43

GO:0018024

sp|Q15911|ZFHX3_HUMAN
Zinc finger homeobox protein 3
Search

ZFHX3

0.82	LOW QUALITY PROTEIN: zinc finger homeobox protein 3

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:1904059	regulation of locomotor rhythm
0.42	GO:0045662	negative regulation of myoblast differentiation
0.41	GO:0045663	positive regulation of myoblast differentiation
0.41	GO:0007050	cell cycle arrest
0.41	GO:0048513	animal organ development
0.40	GO:0071559	response to transforming growth factor beta
0.40	GO:0007623	circadian rhythm

0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.40	GO:0001047	core promoter binding
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.38	GO:0019899	enzyme binding
0.30	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.30	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.30	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0005739	mitochondrion
0.36	GO:0044446	intracellular organelle part

sp|Q15915|ZIC1_HUMAN
Zinc finger protein ZIC 1
Search

ZIC1

0.66	Zinc finger of the cerebellum 1

0.56	GO:0007420	brain development
0.48	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.47	GO:0008589	regulation of smoothened signaling pathway
0.47	GO:0061351	neural precursor cell proliferation
0.46	GO:0007628	adult walking behavior
0.46	GO:0021510	spinal cord development
0.46	GO:0042307	positive regulation of protein import into nucleus
0.46	GO:0007389	pattern specification process
0.44	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0006366	transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.46	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q15916|ZBTB6_HUMAN
Zinc finger and BTB domain-containing protein 6
Search

ZBTB6

0.90	Zinc finger and BTB domain-containing protein 6

0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.33	GO:0006886	intracellular protein transport

0.51	GO:0003676	nucleic acid binding
0.42	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding
0.33	GO:0008536	Ran GTPase binding

0.48	GO:0005634	nucleus
0.47	GO:0005739	mitochondrion

sp|Q15928|ZN141_HUMAN
Zinc finger protein 141
Search

0.78	Zinc finger protein 736

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:0021762	substantia nigra development
0.35	GO:0030154	cell differentiation
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0044092	negative regulation of molecular function
0.30	GO:0060173	limb development
0.30	GO:0009653	anatomical structure morphogenesis

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003682	chromatin binding

0.45	GO:0005622	intracellular
0.40	GO:0031974	membrane-enclosed lumen
0.40	GO:0043227	membrane-bounded organelle
0.38	GO:0043228	non-membrane-bounded organelle
0.37	GO:0044422	organelle part

sp|Q15929|ZNF56_HUMAN
Putative zinc finger protein 56
Search

0.10	Putative zinc finger protein 56

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.41	GO:0070895	negative regulation of transposon integration
0.40	GO:0006351	transcription, DNA-templated
0.37	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.41	GO:0043227	membrane-bounded organelle
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043228	non-membrane-bounded organelle
0.37	GO:0044422	organelle part
0.35	GO:0043230	extracellular organelle
0.34	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|Q15935|ZNF77_HUMAN
Zinc finger protein 77
Search

ZNF699

0.76	Zinc finger domain-containing protein (Fragment)

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0033554	cellular response to stress
0.33	GO:0071300	cellular response to retinoic acid
0.33	GO:0007283	spermatogenesis
0.33	GO:0009408	response to heat

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.36	GO:0004930	G-protein coupled receptor activity
0.36	GO:0004984	olfactory receptor activity
0.35	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q15937|ZNF79_HUMAN
Zinc finger protein 79
Search

ZNF79

0.81	Zinc finger protein 79

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0007275	multicellular organism development
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.51	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding
0.33	GO:0004930	G-protein coupled receptor activity

0.43	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q15940|ZNF67_HUMAN
Putative zinc finger protein 726P1
Search

sp|Q15942|ZYX_HUMAN
Zyxin
Search

ZYX

0.97	Putative focal adhesion adaptor protein paxillin (Fragment)

0.57	GO:0043149	stress fiber assembly
0.55	GO:0071346	cellular response to interferon-gamma
0.54	GO:0007179	transforming growth factor beta receptor signaling pathway
0.53	GO:0007160	cell-matrix adhesion
0.53	GO:0007229	integrin-mediated signaling pathway
0.40	GO:0060030	dorsal convergence
0.40	GO:0050727	regulation of inflammatory response
0.35	GO:0007267	cell-cell signaling
0.34	GO:0016032	viral process
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.53	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding
0.35	GO:0003723	RNA binding

0.58	GO:0005925	focal adhesion
0.56	GO:0097517	contractile actin filament bundle
0.55	GO:0042641	actomyosin
0.54	GO:0045335	phagocytic vesicle
0.54	GO:0005913	cell-cell adherens junction
0.50	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.34	GO:0005887	integral component of plasma membrane

sp|Q15973|ZN124_HUMAN
Zinc finger protein 124
Search

0.94	Zinc finger protein 20

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0006351	transcription, DNA-templated
0.35	GO:1902679	negative regulation of RNA biosynthetic process

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.39	GO:0005515	protein binding
0.36	GO:0003714	transcription corepressor activity

0.45	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle

sp|Q16048|MCHL1_HUMAN
Putative pro-MCH-like protein 1
Search

PMCHL1

0.81	Pro-melanin concentrating hormone

0.78	GO:0007268	chemical synaptic transmission
0.76	GO:0010469	regulation of receptor activity
0.61	GO:0007631	feeding behavior
0.40	GO:0007218	neuropeptide signaling pathway
0.37	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep
0.37	GO:0032227	negative regulation of synaptic transmission, dopaminergic
0.36	GO:0007595	lactation
0.36	GO:0045776	negative regulation of blood pressure
0.36	GO:0048168	regulation of neuronal synaptic plasticity
0.36	GO:0002027	regulation of heart rate

0.87	GO:0030354	melanin-concentrating hormone activity
0.37	GO:0031777	type 1 melanin-concentrating hormone receptor binding

0.48	GO:0005634	nucleus
0.39	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q16082|HSPB2_HUMAN
Heat shock protein beta-2
Search

HSPB2

0.97	Heat shock protein beta-2

0.65	GO:0007525	somatic muscle development
0.38	GO:0009408	response to heat
0.37	GO:0006986	response to unfolded protein
0.36	GO:0043085	positive regulation of catalytic activity
0.34	GO:0045766	positive regulation of angiogenesis
0.34	GO:0061077	chaperone-mediated protein folding

0.79	GO:0005212	structural constituent of eye lens
0.36	GO:0008047	enzyme activator activity
0.35	GO:0005515	protein binding

0.37	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

sp|Q16099|GRIK4_HUMAN
Glutamate receptor ionotropic, kainate 4
Search

GRIK4

0.97	Glutamate ionotropic receptor kainate type subunit 4

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.46	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane
0.45	GO:0035249	synaptic transmission, glutamatergic
0.36	GO:0043525	positive regulation of neuron apoptotic process
0.36	GO:0043113	receptor clustering
0.36	GO:0071333	cellular response to glucose stimulus
0.36	GO:0006621	protein retention in ER lumen
0.35	GO:0031960	response to corticosteroid

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.45	GO:0099094	ligand-gated cation channel activity
0.45	GO:0005272	sodium channel activity
0.44	GO:0098782	mechanosensitived potassium channel activity
0.36	GO:0030165	PDZ domain binding
0.35	GO:0017124	SH3 domain binding
0.35	GO:0042802	identical protein binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.61	GO:0032983	kainate selective glutamate receptor complex
0.58	GO:0042734	presynaptic membrane
0.40	GO:0005783	endoplasmic reticulum
0.39	GO:0005634	nucleus
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon
0.38	GO:0043204	perikaryon
0.37	GO:0043679	axon terminus

sp|Q16134|ETFD_HUMAN
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
Search

ETFDH

0.53	Electron transfer flavoprotein ubiquinone oxidoreductase

0.65	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.57	GO:0006979	response to oxidative stress
0.56	GO:0022904	respiratory electron transport chain

0.72	GO:0048039	ubiquinone binding
0.70	GO:0016649	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor
0.56	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0043783	oxidoreductase activity, oxidizing metal ions with flavin as acceptor
0.52	GO:0009055	electron transfer activity
0.37	GO:0046872	metal ion binding
0.37	GO:0050660	flavin adenine dinucleotide binding

0.65	GO:0031305	integral component of mitochondrial inner membrane
0.56	GO:0045251	electron transfer flavoprotein complex
0.48	GO:0005759	mitochondrial matrix
0.48	GO:0098798	mitochondrial protein complex

0.70

EC:1.5.5

GO:0016649

sp|Q16143|SYUB_HUMAN
Beta-synuclein
Search

SNCB

0.91	Gamma-synuclein

0.67	GO:0014059	regulation of dopamine secretion
0.61	GO:0042417	dopamine metabolic process
0.59	GO:0043524	negative regulation of neuron apoptotic process
0.58	GO:0050808	synapse organization
0.56	GO:0007268	chemical synaptic transmission
0.49	GO:0051945	negative regulation of catecholamine uptake involved in synaptic transmission
0.49	GO:0051621	regulation of norepinephrine uptake
0.49	GO:1903284	positive regulation of glutathione peroxidase activity
0.49	GO:1903285	positive regulation of hydrogen peroxide catabolic process
0.49	GO:1904715	negative regulation of chaperone-mediated autophagy

0.62	GO:1903136	cuprous ion binding
0.51	GO:0005509	calcium ion binding
0.48	GO:0048156	tau protein binding
0.48	GO:0050544	arachidonic acid binding
0.48	GO:0043014	alpha-tubulin binding
0.47	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.47	GO:0030544	Hsp70 protein binding
0.46	GO:0019894	kinesin binding
0.46	GO:0070840	dynein complex binding
0.46	GO:0051219	phosphoprotein binding

0.59	GO:0016234	inclusion body
0.55	GO:0045202	synapse
0.48	GO:0031092	platelet alpha granule membrane
0.48	GO:0043025	neuronal cell body
0.47	GO:0030424	axon
0.47	GO:0030426	growth cone
0.46	GO:0005739	mitochondrion
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005615	extracellular space
0.44	GO:0005829	cytosol

0.37

GO:0016491

sp|Q16181|SEPT7_HUMAN
Septin-7
Search

SEPT7

0.92	Septin-7 isoform A

0.42	GO:0016476	regulation of embryonic cell shape
0.40	GO:0060271	cilium assembly
0.40	GO:0007283	spermatogenesis
0.38	GO:1902857	positive regulation of non-motile cilium assembly
0.38	GO:0051301	cell division
0.38	GO:0030154	cell differentiation
0.38	GO:0051291	protein heterooligomerization
0.38	GO:0031270	pseudopodium retraction
0.38	GO:0007049	cell cycle
0.37	GO:0097061	dendritic spine organization

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0045296	cadherin binding
0.36	GO:0042802	identical protein binding
0.35	GO:0046982	protein heterodimerization activity
0.33	GO:0005198	structural molecule activity

0.85	GO:0031105	septin complex
0.41	GO:0032154	cleavage furrow
0.41	GO:0030496	midbody
0.41	GO:0005930	axoneme
0.40	GO:0016324	apical plasma membrane
0.40	GO:0000777	condensed chromosome kinetochore
0.40	GO:0005819	spindle
0.38	GO:0097227	sperm annulus
0.38	GO:0097517	contractile actin filament bundle
0.38	GO:0042641	actomyosin

sp|Q16186|ADRM1_HUMAN
Proteasomal ubiquitin receptor ADRM1
Search

ADRM1

0.90	Adhesion regulating molecule 1

0.56	GO:0010950	positive regulation of endopeptidase activity
0.53	GO:0043248	proteasome assembly
0.52	GO:0006368	transcription elongation from RNA polymerase II promoter
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0060399	positive regulation of growth hormone receptor signaling pathway
0.37	GO:0060009	Sertoli cell development
0.37	GO:0072520	seminiferous tubule development
0.37	GO:0033081	regulation of T cell differentiation in thymus
0.37	GO:0042699	follicle-stimulating hormone signaling pathway
0.37	GO:0060612	adipose tissue development

0.58	GO:0061133	endopeptidase activator activity
0.55	GO:0070628	proteasome binding
0.53	GO:0002020	protease binding
0.46	GO:0043130	ubiquitin binding

0.61	GO:0005634	nucleus
0.51	GO:1905369	endopeptidase complex
0.49	GO:0005737	cytoplasm
0.46	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q16204|CCDC6_HUMAN
Coiled-coil domain-containing protein 6
Search

CCDC6

0.95	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 6

0.43	GO:0007165	signal transduction
0.39	GO:0055085	transmembrane transport
0.38	GO:0007010	cytoskeleton organization
0.37	GO:0018108	peptidyl-tyrosine phosphorylation

0.43	GO:0017124	SH3 domain binding
0.39	GO:0005200	structural constituent of cytoskeleton
0.37	GO:0004713	protein tyrosine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0005829	cytosol
0.40	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.37

GO:0004713

sp|Q16206|ENOX2_HUMAN
Ecto-NOX disulfide-thiol exchanger 2
Search

ENOX2

0.97	Ecto-NOX disulfide-thiol exchanger 2

0.57	GO:0007624	ultradian rhythm
0.40	GO:0055114	oxidation-reduction process
0.36	GO:0040008	regulation of growth
0.35	GO:0016049	cell growth

0.58	GO:0003723	RNA binding
0.48	GO:0015035	protein disulfide oxidoreductase activity
0.34	GO:0005515	protein binding

0.52	GO:0009897	external side of plasma membrane
0.36	GO:0005615	extracellular space
0.34	GO:0005829	cytosol

sp|Q16222|UAP1_HUMAN
UDP-N-acetylhexosamine pyrophosphorylase
Search

UAP1

0.89	UDP-N-acetylhexosamine pyrophosphorylase

0.46	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.45	GO:0046349	amino sugar biosynthetic process
0.44	GO:0009226	nucleotide-sugar biosynthetic process
0.36	GO:0016310	phosphorylation
0.36	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.36	GO:0038065	collagen-activated signaling pathway
0.36	GO:0018212	peptidyl-tyrosine modification

0.75	GO:0070569	uridylyltransferase activity
0.50	GO:0042802	identical protein binding
0.37	GO:0016301	kinase activity
0.36	GO:0030246	carbohydrate binding
0.36	GO:0038064	collagen receptor activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.42	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016773

sp|Q16236|NF2L2_HUMAN
Nuclear factor erythroid 2-related factor 2
Search

NFE2L2

0.97	Nuclear factor, erythroid 2 like 2

0.75	GO:0034599	cellular response to oxidative stress
0.59	GO:1903786	regulation of glutathione biosynthetic process
0.58	GO:0071499	cellular response to laminar fluid shear stress
0.58	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.58	GO:0036499	PERK-mediated unfolded protein response
0.57	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.57	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.57	GO:1901032	negative regulation of response to reactive oxygen species
0.57	GO:2001039	negative regulation of cellular response to drug
0.56	GO:1903205	regulation of hydrogen peroxide-induced cell death

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0003677	DNA binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0019904	protein domain specific binding
0.39	GO:0001221	transcription cofactor binding
0.38	GO:0046982	protein heterodimerization activity
0.35	GO:0120013	intermembrane lipid transfer activity
0.33	GO:0047485	protein N-terminus binding

0.61	GO:0005634	nucleus
0.52	GO:0005813	centrosome
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.48	GO:0000785	chromatin
0.48	GO:0032993	protein-DNA complex
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0005886	plasma membrane
0.37	GO:0005667	transcription factor complex

sp|Q16254|E2F4_HUMAN
Transcription factor E2F4
Search

E2F4

0.95	E2F transcription factor 4

0.75	GO:0000278	mitotic cell cycle
0.68	GO:0006884	cell volume homeostasis
0.67	GO:0044843	cell cycle G1/S phase transition
0.66	GO:0002064	epithelial cell development
0.65	GO:0008015	blood circulation
0.64	GO:0060271	cilium assembly
0.63	GO:0009887	animal organ morphogenesis
0.62	GO:0042127	regulation of cell proliferation
0.62	GO:0006366	transcription by RNA polymerase II
0.62	GO:0045944	positive regulation of transcription by RNA polymerase II

0.70	GO:1990841	promoter-specific chromatin binding
0.68	GO:0046983	protein dimerization activity
0.65	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.65	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.63	GO:0019904	protein domain specific binding
0.60	GO:0008134	transcription factor binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0000790	nuclear chromatin
0.58	GO:0005654	nucleoplasm

sp|Q16270|IBP7_HUMAN
Insulin-like growth factor-binding protein 7
Search

IGFBP7

0.97	Insulin like growth factor binding protein like 1

0.79	GO:0001558	regulation of cell growth
0.50	GO:0007155	cell adhesion
0.42	GO:0051414	response to cortisol
0.41	GO:0007566	embryo implantation
0.41	GO:0071228	cellular response to tumor cell
0.41	GO:0050810	regulation of steroid biosynthetic process
0.41	GO:0032526	response to retinoic acid
0.40	GO:0048839	inner ear development
0.39	GO:0032870	cellular response to hormone stimulus
0.39	GO:0009408	response to heat

0.84	GO:0005520	insulin-like growth factor binding
0.36	GO:0042802	identical protein binding
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005509	calcium ion binding
0.32	GO:0043236	laminin binding

0.66	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0004252

sp|Q16280|CNGA2_HUMAN
Cyclic nucleotide-gated olfactory channel
Search

CNGA2

0.97	Cyclic nucleotide-gated olfactory channel

0.60	GO:0034220	ion transmembrane transport
0.57	GO:0071804	cellular potassium ion transport
0.50	GO:0007608	sensory perception of smell
0.47	GO:0042391	regulation of membrane potential
0.41	GO:0032026	response to magnesium ion
0.40	GO:0051591	response to cAMP
0.40	GO:0046549	retinal cone cell development
0.40	GO:0031960	response to corticosteroid
0.36	GO:0007165	signal transduction
0.35	GO:0060271	cilium assembly

0.70	GO:0005216	ion channel activity
0.58	GO:0022832	voltage-gated channel activity
0.57	GO:0015079	potassium ion transmembrane transporter activity
0.46	GO:0030553	cGMP binding
0.42	GO:0022834	ligand-gated channel activity
0.41	GO:0030552	cAMP binding
0.40	GO:0005516	calmodulin binding
0.40	GO:0008022	protein C-terminus binding
0.36	GO:0004871	signal transducer activity

0.43	GO:0005887	integral component of plasma membrane
0.42	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.41	GO:0060170	ciliary membrane
0.41	GO:0043204	perikaryon
0.40	GO:0001750	photoreceptor outer segment
0.39	GO:0030425	dendrite
0.35	GO:0030660	Golgi-associated vesicle membrane
0.34	GO:0000139	Golgi membrane

sp|Q16281|CNGA3_HUMAN
Cyclic nucleotide-gated cation channel alpha-3
Search

CNGA3

0.95	Cyclic nucleotide-gated channel cone photoreceptor subunit alpha

0.60	GO:0034220	ion transmembrane transport
0.54	GO:0071804	cellular potassium ion transport
0.46	GO:0042391	regulation of membrane potential
0.44	GO:0007600	sensory perception
0.43	GO:0032026	response to magnesium ion
0.42	GO:0051591	response to cAMP
0.42	GO:0031960	response to corticosteroid
0.42	GO:0046549	retinal cone cell development
0.36	GO:0007165	signal transduction
0.35	GO:0051290	protein heterotetramerization

0.70	GO:0005216	ion channel activity
0.57	GO:0022836	gated channel activity
0.54	GO:0030553	cGMP binding
0.54	GO:0015079	potassium ion transmembrane transporter activity
0.42	GO:0008022	protein C-terminus binding
0.39	GO:0030552	cAMP binding
0.37	GO:0005516	calmodulin binding
0.36	GO:0004871	signal transducer activity

0.45	GO:1902495	transmembrane transporter complex
0.43	GO:0042622	photoreceptor outer segment membrane
0.43	GO:0043204	perikaryon
0.43	GO:0005887	integral component of plasma membrane
0.41	GO:0030425	dendrite
0.35	GO:0005737	cytoplasm
0.33	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0031984	organelle subcompartment
0.33	GO:0012505	endomembrane system

sp|Q16288|NTRK3_HUMAN
NT-3 growth factor receptor
Search

NTRK3

0.67	Tyrosine-protein kinase receptor

0.80	GO:0038179	neurotrophin signaling pathway
0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.52	GO:0048687	positive regulation of sprouting of injured axon
0.52	GO:0048690	regulation of axon extension involved in regeneration
0.51	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.51	GO:0050927	positive regulation of positive chemotaxis
0.51	GO:0032148	activation of protein kinase B activity
0.51	GO:0070306	lens fiber cell differentiation
0.50	GO:0045773	positive regulation of axon extension

0.82	GO:0005030	neurotrophin receptor activity
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.49	GO:0002039	p53 binding
0.36	GO:0043121	neurotrophin binding
0.35	GO:0004675	transmembrane receptor protein serine/threonine kinase activity

0.65	GO:0005887	integral component of plasma membrane
0.47	GO:0043235	receptor complex
0.37	GO:0005737	cytoplasm
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle

0.80

EC:2.7.10.1

GO:0004714

sp|Q16322|KCA10_HUMAN
Potassium voltage-gated channel subfamily A member 10
Search

KCNA10

0.97	cGMP-gated potassium channel

0.78	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.39	GO:0071286	cellular response to magnesium ion
0.39	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.38	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.38	GO:0010960	magnesium ion homeostasis
0.38	GO:0001964	startle response
0.38	GO:0019228	neuronal action potential
0.38	GO:0007405	neuroblast proliferation

0.78	GO:0005249	voltage-gated potassium channel activity
0.38	GO:0097718	disordered domain specific binding
0.36	GO:0005221	intracellular cyclic nucleotide activated cation channel activity

0.78	GO:0008076	voltage-gated potassium channel complex
0.38	GO:0044224	juxtaparanode region of axon
0.38	GO:0043679	axon terminus
0.38	GO:0033270	paranode region of axon
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.36	GO:0009986	cell surface
0.36	GO:0030054	cell junction

sp|Q16342|PDCD2_HUMAN
Programmed cell death protein 2
Search

PDCD2

0.90	Programmed cell death 2 alternative transcript

0.60	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.58	GO:1901532	regulation of hematopoietic progenitor cell differentiation
0.56	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0060218	hematopoietic stem cell differentiation
0.45	GO:0030218	erythrocyte differentiation
0.43	GO:0007088	regulation of mitotic nuclear division
0.41	GO:0012501	programmed cell death
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.49	GO:0019899	enzyme binding
0.35	GO:0003677	DNA binding
0.35	GO:0046872	metal ion binding
0.32	GO:0008408	3'-5' exonuclease activity
0.32	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003723	RNA binding
0.31	GO:1901265	nucleoside phosphate binding
0.31	GO:0036094	small molecule binding

0.48	GO:0005737	cytoplasm
0.38	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.32	GO:0042575	DNA polymerase complex
0.32	GO:0044427	chromosomal part
0.32	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

0.32

EC:2.7.7.7

GO:0003887

sp|Q16348|S15A2_HUMAN
Solute carrier family 15 member 2
Search

SLC15A2

0.96	Solute carrier family 15 (oligopeptide transporter), member 2

0.75	GO:0006857	oligopeptide transport
0.54	GO:0055085	transmembrane transport
0.45	GO:0001878	response to yeast
0.38	GO:0015804	neutral amino acid transport
0.37	GO:0015031	protein transport
0.36	GO:0015893	drug transport
0.35	GO:1901998	toxin transport
0.34	GO:0015992	proton transport
0.33	GO:0006508	proteolysis

0.69	GO:0035673	oligopeptide transmembrane transporter activity
0.44	GO:0042936	dipeptide transporter activity
0.39	GO:0015291	secondary active transmembrane transporter activity
0.38	GO:0015175	neutral amino acid transmembrane transporter activity
0.36	GO:0042895	antibiotic transmembrane transporter activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0005515	protein binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity

0.38	GO:0070062	extracellular exosome
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0005903	brush border

sp|Q16352|AINX_HUMAN
Alpha-internexin
Search

INA

0.97	Internexin neuronal intermediate filament protein alpha

0.73	GO:0007399	nervous system development
0.58	GO:0120036	plasma membrane bounded cell projection organization
0.58	GO:0060052	neurofilament cytoskeleton organization
0.58	GO:0048468	cell development
0.55	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.38	GO:0048857	neural nucleus development
0.38	GO:0060322	head development
0.37	GO:0045110	intermediate filament bundle assembly
0.37	GO:0048513	animal organ development

0.62	GO:0005198	structural molecule activity
0.36	GO:0005515	protein binding
0.34	GO:0015643	toxic substance binding

0.85	GO:0005883	neurofilament
0.55	GO:0043209	myelin sheath
0.54	GO:0036464	cytoplasmic ribonucleoprotein granule
0.54	GO:0031965	nuclear membrane
0.49	GO:0005654	nucleoplasm
0.49	GO:0097418	neurofibrillary tangle
0.36	GO:0005615	extracellular space
0.36	GO:0030424	axon
0.35	GO:0031594	neuromuscular junction
0.35	GO:0014069	postsynaptic density

sp|Q16363|LAMA4_HUMAN
Laminin subunit alpha-4
Search

LAMA4

0.78	Laminin subunit alpha 4

0.75	GO:0045995	regulation of embryonic development
0.71	GO:0030334	regulation of cell migration
0.71	GO:0007155	cell adhesion
0.69	GO:0030155	regulation of cell adhesion
0.48	GO:0050873	brown fat cell differentiation
0.47	GO:0001568	blood vessel development
0.37	GO:0016203	muscle attachment
0.37	GO:0007017	microtubule-based process
0.37	GO:0030903	notochord development
0.37	GO:0001885	endothelial cell development

0.66	GO:0005102	receptor binding
0.37	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0005201	extracellular matrix structural constituent

0.49	GO:0005605	basal lamina
0.44	GO:0005615	extracellular space
0.37	GO:0005874	microtubule
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0043230	extracellular organelle

sp|Q16378|PROL4_HUMAN
Proline-rich protein 4
Search

PRR4

0.93	Proline-rich protein 4

0.85	GO:0001895	retina homeostasis
0.78	GO:0007601	visual perception

0.73

GO:0005615

extracellular space

sp|Q16384|SSX1_HUMAN
Protein SSX1
Search

0.97	SSX family member 1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0051253	negative regulation of RNA metabolic process
0.51	GO:0010558	negative regulation of macromolecule biosynthetic process
0.51	GO:0031327	negative regulation of cellular biosynthetic process
0.40	GO:0006351	transcription, DNA-templated

0.56	GO:0003714	transcription corepressor activity
0.50	GO:0003676	nucleic acid binding
0.38	GO:0005515	protein binding
0.38	GO:0003713	transcription coactivator activity

0.58	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q16385|SSX2_HUMAN
Protein SSX2
Search

0.97	SSX family member 3

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process
0.50	GO:0031327	negative regulation of cellular biosynthetic process
0.40	GO:0006351	transcription, DNA-templated

0.56	GO:0003714	transcription corepressor activity
0.50	GO:0003676	nucleic acid binding
0.39	GO:0005515	protein binding
0.38	GO:0003713	transcription coactivator activity

0.58	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q16394|EXT1_HUMAN
Exostosin-1
Search

EXT1

0.88	Exostosin glycosyltransferase 1

0.85	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.74	GO:0043413	macromolecule glycosylation
0.60	GO:0036211	protein modification process
0.59	GO:0072498	embryonic skeletal joint development
0.58	GO:0021772	olfactory bulb development
0.57	GO:0007492	endoderm development
0.56	GO:0007498	mesoderm development
0.56	GO:0001503	ossification
0.55	GO:0044267	cellular protein metabolic process
0.55	GO:0007369	gastrulation

0.82	GO:0015020	glucuronosyltransferase activity
0.62	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.36	GO:0046872	metal ion binding
0.36	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity

0.70	GO:0005783	endoplasmic reticulum
0.51	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.51	GO:0005794	Golgi apparatus
0.49	GO:0031984	organelle subcompartment
0.39	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.82

EC:2.4.1.17

GO:0015020

sp|Q16401|PSMD5_HUMAN
26S proteasome non-ATPase regulatory subunit 5
Search

PSMD5

0.95	26S proteasome non-ATPase regulatory subunit 5

0.81	GO:0043248	proteasome assembly
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation
0.36	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.36	GO:0070498	interleukin-1-mediated signaling pathway
0.36	GO:0038061	NIK/NF-kappaB signaling

0.33

GO:0005515

protein binding

0.69	GO:1905369	endopeptidase complex
0.56	GO:0043234	protein complex
0.43	GO:0044424	intracellular part
0.34	GO:0043233	organelle lumen
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0044425	membrane part

sp|Q16445|GBRA6_HUMAN
Gamma-aminobutyric acid receptor subunit alpha-6
Search

GABRA6

0.97	Neurotransmitter receptor subunit

0.81	GO:0007214	gamma-aminobutyric acid signaling pathway
0.72	GO:0006821	chloride transport
0.59	GO:0034220	ion transmembrane transport
0.49	GO:2001023	regulation of response to drug
0.47	GO:0007417	central nervous system development
0.36	GO:0051932	synaptic transmission, GABAergic
0.35	GO:0051291	protein heterooligomerization

0.82	GO:0004890	GABA-A receptor activity
0.74	GO:0005230	extracellular ligand-gated ion channel activity
0.41	GO:0005254	chloride channel activity
0.40	GO:0008503	benzodiazepine receptor activity
0.35	GO:0099095	ligand-gated anion channel activity
0.34	GO:0022835	transmitter-gated channel activity
0.32	GO:0008144	drug binding

0.55	GO:0005886	plasma membrane
0.51	GO:1902711	GABA-A receptor complex
0.42	GO:0034707	chloride channel complex
0.41	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0098793	presynapse

sp|Q16473|TENXA_HUMAN
Putative tenascin-XA
Search

0.10	Putative tenascin-XA

0.85	GO:0030199	collagen fibril organization
0.44	GO:0043506	regulation of JUN kinase activity
0.43	GO:0007160	cell-matrix adhesion
0.43	GO:0006641	triglyceride metabolic process
0.42	GO:0098609	cell-cell adhesion
0.40	GO:0006631	fatty acid metabolic process

0.43	GO:0005518	collagen binding
0.43	GO:0008201	heparin binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005615	extracellular space
0.48	GO:1903561	extracellular vesicle

sp|Q16478|GRIK5_HUMAN
Glutamate receptor ionotropic, kainate 5
Search

GRIK5

0.96	Glutamate ionotropic receptor kainate type subunit 5

0.80	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.55	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane
0.52	GO:0035249	synaptic transmission, glutamatergic
0.39	GO:0043525	positive regulation of neuron apoptotic process
0.39	GO:0043113	receptor clustering
0.39	GO:0071333	cellular response to glucose stimulus
0.38	GO:0006621	protein retention in ER lumen
0.36	GO:0051649	establishment of localization in cell

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.51	GO:0099094	ligand-gated cation channel activity
0.51	GO:0005272	sodium channel activity
0.50	GO:0098782	mechanosensitived potassium channel activity
0.39	GO:0030165	PDZ domain binding
0.38	GO:0017124	SH3 domain binding
0.37	GO:0042802	identical protein binding
0.35	GO:0005391	sodium:potassium-exchanging ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.61	GO:0032983	kainate selective glutamate receptor complex
0.57	GO:0042734	presynaptic membrane
0.46	GO:0005783	endoplasmic reticulum
0.43	GO:0005634	nucleus
0.40	GO:0030425	dendrite
0.40	GO:0043204	perikaryon
0.40	GO:0043195	terminal bouton
0.38	GO:0014069	postsynaptic density

0.35

EC:3.6.3.9

GO:0005391

sp|Q16512|PKN1_HUMAN
Serine/threonine-protein kinase N1
Search

PKN1

0.49	Serine/threonine-protein kinase N1

0.63	GO:0006468	protein phosphorylation
0.59	GO:0007165	signal transduction
0.55	GO:0002634	regulation of germinal center formation
0.55	GO:0001783	B cell apoptotic process
0.54	GO:0030889	negative regulation of B cell proliferation
0.53	GO:0001782	B cell homeostasis
0.53	GO:0048536	spleen development
0.53	GO:0002637	regulation of immunoglobulin production
0.53	GO:0010631	epithelial cell migration
0.53	GO:0018210	peptidyl-threonine modification

0.83	GO:0017049	GTP-Rho binding
0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0050681	androgen receptor binding
0.54	GO:0035173	histone kinase activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0048365	Rac GTPase binding
0.53	GO:0005080	protein kinase C binding

0.53	GO:0097610	cell surface furrow
0.52	GO:0030496	midbody
0.52	GO:0032155	cell division site part
0.49	GO:0005768	endosome
0.43	GO:0005634	nucleus
0.42	GO:0043234	protein complex
0.35	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

0.70

GO:0004674

sp|Q16513|PKN2_HUMAN
Serine/threonine-protein kinase N2
Search

PKN2

0.49	Serine/threonine-protein kinase N2

0.63	GO:0006468	protein phosphorylation
0.60	GO:0007165	signal transduction
0.57	GO:0045070	positive regulation of viral genome replication
0.56	GO:0043297	apical junction assembly
0.56	GO:0032467	positive regulation of cytokinesis
0.55	GO:0010631	epithelial cell migration
0.54	GO:0045931	positive regulation of mitotic cell cycle
0.53	GO:2000145	regulation of cell motility
0.47	GO:0018209	peptidyl-serine modification
0.37	GO:0006915	apoptotic process

0.79	GO:0017049	GTP-Rho binding
0.66	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0042826	histone deacetylase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0045296	cadherin binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0070063	RNA polymerase binding
0.35	GO:0003723	RNA binding
0.34	GO:0004386	helicase activity

0.56	GO:0097610	cell surface furrow
0.55	GO:0030496	midbody
0.55	GO:0030027	lamellipodium
0.54	GO:0032155	cell division site part
0.54	GO:0043296	apical junction complex
0.53	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0045111	intermediate filament cytoskeleton
0.52	GO:0005813	centrosome
0.52	GO:0016604	nuclear body
0.48	GO:0005829	cytosol

0.66

GO:0004674

sp|Q16514|TAF12_HUMAN
Transcription initiation factor TFIID subunit 12
Search

TAF12

0.89	Transcription initiation factor TFIID subunit 12

0.69	GO:0006352	DNA-templated transcription, initiation
0.59	GO:0006413	translational initiation
0.57	GO:0043966	histone H3 acetylation
0.52	GO:0006366	transcription by RNA polymerase II
0.51	GO:0051091	positive regulation of DNA binding transcription factor activity
0.47	GO:0065004	protein-DNA complex assembly
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.34	GO:0006354	DNA-templated transcription, elongation

0.74	GO:0046982	protein heterodimerization activity
0.60	GO:0003743	translation initiation factor activity
0.55	GO:0004402	histone acetyltransferase activity
0.51	GO:0008134	transcription factor binding
0.50	GO:0003713	transcription coactivator activity
0.43	GO:0003700	DNA binding transcription factor activity
0.42	GO:0003677	DNA binding

0.82	GO:0046695	SLIK (SAGA-like) complex
0.80	GO:0000124	SAGA complex
0.80	GO:0005669	transcription factor TFIID complex
0.55	GO:0030914	STAGA complex
0.54	GO:0033276	transcription factor TFTC complex
0.41	GO:0000125	PCAF complex
0.30	GO:0016020	membrane

0.55

GO:0004402

sp|Q16515|ASIC2_HUMAN
Acid-sensing ion channel 2
Search

ASIC2

0.84	Amiloride-sensitive sodium channel subunit alpha

0.73	GO:0035725	sodium ion transmembrane transport
0.53	GO:0050915	sensory perception of sour taste
0.52	GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
0.50	GO:0035418	protein localization to synapse
0.49	GO:0010447	response to acidic pH
0.49	GO:0050974	detection of mechanical stimulus involved in sensory perception
0.49	GO:0051965	positive regulation of synapse assembly
0.48	GO:0019229	regulation of vasoconstriction
0.47	GO:0007605	sensory perception of sound
0.47	GO:0042391	regulation of membrane potential

0.77	GO:0005272	sodium channel activity
0.70	GO:0099094	ligand-gated cation channel activity
0.37	GO:0005515	protein binding

0.48	GO:0043197	dendritic spine
0.47	GO:0043025	neuronal cell body
0.44	GO:0005887	integral component of plasma membrane
0.34	GO:0005794	Golgi apparatus

sp|Q16517|NNAT_HUMAN
Neuronatin
Search

NNAT

0.97	Neuronatin isoform alpha

0.79	GO:0007420	brain development
0.58	GO:0032024	positive regulation of insulin secretion
0.44	GO:0009749	response to glucose
0.42	GO:0030182	neuron differentiation
0.39	GO:0009249	protein lipoylation

0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q16518|RPE65_HUMAN
Retinoid isomerohydrolase
Search

RPE65

0.97	Retinal Mueller cells isomerohydrolase

0.66	GO:0001523	retinoid metabolic process
0.62	GO:1901827	zeaxanthin biosynthetic process
0.61	GO:0034308	primary alcohol metabolic process
0.61	GO:0034754	cellular hormone metabolic process
0.57	GO:0007468	regulation of rhodopsin gene expression
0.57	GO:0050908	detection of light stimulus involved in visual perception
0.56	GO:0071257	cellular response to electrical stimulus
0.55	GO:0001895	retina homeostasis
0.54	GO:0008286	insulin receptor signaling pathway
0.54	GO:0060042	retina morphogenesis in camera-type eye

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.71	GO:0052885	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
0.68	GO:1901612	cardiolipin binding
0.67	GO:0031210	phosphatidylcholine binding
0.66	GO:0001786	phosphatidylserine binding
0.60	GO:0004744	retinal isomerase activity
0.53	GO:0046872	metal ion binding
0.50	GO:0052884	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
0.36	GO:0050251	retinol isomerase activity
0.34	GO:0005515	protein binding

0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0044297	cell body
0.37	GO:0031090	organelle membrane
0.37	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol

0.75	EC:1.13.11	GO:0016702
0.71	KEGG:R08388	GO:0052885

sp|Q16520|BATF_HUMAN
Basic leucine zipper transcriptional factor ATF-like
Search

BATF

0.97	Basic leucine zipper transcriptional factor ATF

0.71	GO:0030154	cell differentiation
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.70	GO:0072538	T-helper 17 type immune response
0.69	GO:0042092	type 2 immune response
0.68	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.68	GO:0042832	defense response to protozoan
0.68	GO:0001773	myeloid dendritic cell activation
0.68	GO:0002287	alpha-beta T cell activation involved in immune response
0.67	GO:0035710	CD4-positive, alpha-beta T cell activation
0.67	GO:0002312	B cell activation involved in immune response

0.62	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0005515	protein binding

0.55	GO:0005654	nucleoplasm
0.42	GO:0005737	cytoplasm

sp|Q16526|CRY1_HUMAN
Cryptochrome-1
Search

CRY1

0.80	Cryptochrome circadian clock 1

0.72	GO:0009649	entrainment of circadian clock
0.70	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.70	GO:0006975	DNA damage induced protein phosphorylation
0.70	GO:2000847	negative regulation of corticosteroid hormone secretion
0.69	GO:0033762	response to glucagon
0.69	GO:0042754	negative regulation of circadian rhythm
0.68	GO:2000849	regulation of glucocorticoid secretion
0.68	GO:2000001	regulation of DNA damage checkpoint
0.67	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.66	GO:0032922	circadian regulation of gene expression

0.67	GO:0035257	nuclear hormone receptor binding
0.66	GO:0019902	phosphatase binding
0.64	GO:0042826	histone deacetylase binding
0.64	GO:0001047	core promoter binding
0.60	GO:0000989	transcription factor activity, transcription factor binding
0.60	GO:0019901	protein kinase binding
0.59	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.47	GO:0009881	photoreceptor activity
0.44	GO:0016829	lyase activity
0.38	GO:1901265	nucleoside phosphate binding

0.56	GO:0097381	photoreceptor disc membrane
0.56	GO:0042622	photoreceptor outer segment membrane
0.53	GO:0005634	nucleus
0.49	GO:0005739	mitochondrion
0.46	GO:0005829	cytosol
0.44	GO:0005667	transcription factor complex
0.35	GO:0005576	extracellular region
0.32	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.44

EC:4

GO:0016829

sp|Q16527|CSRP2_HUMAN
Cysteine and glycine-rich protein 2
Search

CSRP2

0.93	Cysteine and glycine rich protein 2

0.39	GO:0030154	cell differentiation
0.38	GO:0032501	multicellular organismal process
0.38	GO:0048856	anatomical structure development
0.34	GO:0034109	homotypic cell-cell adhesion
0.34	GO:0007254	JNK cascade
0.34	GO:0006937	regulation of muscle contraction
0.34	GO:0007599	hemostasis
0.34	GO:0001667	ameboidal-type cell migration
0.34	GO:0042060	wound healing
0.34	GO:0001775	cell activation

0.53	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.42	GO:0005925	focal adhesion
0.41	GO:0097517	contractile actin filament bundle
0.41	GO:0042641	actomyosin
0.40	GO:0005634	nucleus
0.40	GO:0031252	cell leading edge
0.34	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.33	GO:0099512	supramolecular fiber
0.32	GO:0043234	protein complex

sp|Q16531|DDB1_HUMAN
DNA damage-binding protein 1
Search

DDB1

0.88	Damage specific DNA binding protein 1

0.65	GO:0006281	DNA repair
0.58	GO:0046726	positive regulation by virus of viral protein levels in host cell
0.57	GO:1902188	positive regulation of viral release from host cell
0.57	GO:0035518	histone H2A monoubiquitination
0.56	GO:0045070	positive regulation of viral genome replication
0.55	GO:0051702	interaction with symbiont
0.54	GO:0034644	cellular response to UV
0.54	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.54	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.52	GO:0045732	positive regulation of protein catabolic process

0.58	GO:0071987	WD40-repeat domain binding
0.56	GO:0097602	cullin family protein binding
0.53	GO:0030674	protein binding, bridging
0.51	GO:0003684	damaged DNA binding
0.50	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.59	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex
0.57	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.47	GO:0043233	organelle lumen
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|Q16533|SNPC1_HUMAN
snRNA-activating protein complex subunit 1
Search

SNAPC1

0.97	Small nuclear RNA activating complex polypeptide 1

0.68	GO:0042796	snRNA transcription by RNA polymerase III
0.67	GO:0042795	snRNA transcription by RNA polymerase II
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:0010468	regulation of gene expression

0.52	GO:0043565	sequence-specific DNA binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003700	DNA binding transcription factor activity

0.71	GO:0005730	nucleolus
0.68	GO:0019185	snRNA-activating protein complex
0.37	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q16534|HLF_HUMAN
Hepatic leukemia factor
Search

HLF

0.90	HLF, PAR bZIP transcription factor

0.82	GO:0035914	skeletal muscle cell differentiation
0.73	GO:0006366	transcription by RNA polymerase II
0.72	GO:0045944	positive regulation of transcription by RNA polymerase II

0.78	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|Q16537|2A5E_HUMAN
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
Search

PPP2R5E

0.61	Serine/threonine protein phosphatase 2A regulatory subunit

0.78	GO:0043666	regulation of phosphoprotein phosphatase activity
0.60	GO:0007165	signal transduction

0.79	GO:0019888	protein phosphatase regulator activity
0.34	GO:0005515	protein binding

0.80	GO:0000159	protein phosphatase type 2A complex
0.47	GO:0005829	cytosol

sp|Q16538|GP162_HUMAN
Probable G-protein coupled receptor 162
Search

GPR162

0.92	G protein-coupled receptor 162

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0006481	C-terminal protein methylation
0.34	GO:0055114	oxidation-reduction process

0.72	GO:0004930	G-protein coupled receptor activity
0.39	GO:0031418	L-ascorbic acid binding
0.37	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.37	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
0.36	GO:0005506	iron ion binding

0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005886	plasma membrane
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.37	EC:1.14	GO:0016705
0.37	KEGG:R04496	GO:0004671

sp|Q16539|MK14_HUMAN
Mitogen-activated protein kinase 14
Search

MAPK14

0.57	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.59	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration
0.59	GO:2001184	positive regulation of interleukin-12 secretion
0.58	GO:0090336	positive regulation of brown fat cell differentiation
0.58	GO:1905050	positive regulation of metallopeptidase activity
0.58	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.58	GO:0090400	stress-induced premature senescence
0.58	GO:0071223	cellular response to lipoteichoic acid
0.57	GO:1901741	positive regulation of myoblast fusion
0.57	GO:0010759	positive regulation of macrophage chemotaxis

0.81	GO:0004707	MAP kinase activity
0.59	GO:0048273	mitogen-activated protein kinase p38 binding
0.59	GO:0051525	NFAT protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0019903	protein phosphatase binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004708	MAP kinase kinase activity
0.34	GO:0008022	protein C-terminus binding

0.53	GO:0016607	nuclear speck
0.52	GO:0000922	spindle pole
0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|Q16540|RM23_HUMAN
39S ribosomal protein L23, mitochondrial
Search

MRPL23

0.96	Mitochondrial ribosomal protein L23

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.38	GO:0006942	regulation of striated muscle contraction
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0005759	mitochondrial matrix
0.39	GO:0001650	fibrillar center
0.37	GO:0005861	troponin complex
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

sp|Q16543|CDC37_HUMAN
Hsp90 co-chaperone Cdc37
Search

CDC37

0.88	Hsp90 chaperone protein kinase-targeting subunit

0.55	GO:0060330	regulation of response to interferon-gamma
0.54	GO:0098779	positive regulation of mitophagy in response to mitochondrial depolarization
0.49	GO:0060338	regulation of type I interferon-mediated signaling pathway
0.48	GO:0045859	regulation of protein kinase activity
0.47	GO:0050821	protein stabilization
0.46	GO:0010608	posttranscriptional regulation of gene expression
0.43	GO:0006457	protein folding
0.41	GO:0051301	cell division
0.38	GO:0018108	peptidyl-tyrosine phosphorylation
0.36	GO:0038128	ERBB2 signaling pathway

0.77	GO:0019901	protein kinase binding
0.54	GO:0097110	scaffold protein binding
0.54	GO:0031072	heat shock protein binding
0.49	GO:0019887	protein kinase regulator activity
0.46	GO:0051087	chaperone binding
0.44	GO:0051082	unfolded protein binding
0.38	GO:0004713	protein tyrosine kinase activity
0.35	GO:0008022	protein C-terminus binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.55	GO:1990565	HSP90-CDC37 chaperone complex
0.47	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.35	GO:0032587	ruffle membrane
0.34	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.38

GO:0004713

sp|Q16548|B2LA1_HUMAN
Bcl-2-related protein A1
Search

0.78	GO:0043066	negative regulation of apoptotic process
0.56	GO:0001836	release of cytochrome c from mitochondria
0.56	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.55	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.54	GO:0008053	mitochondrial fusion
0.51	GO:0043065	positive regulation of apoptotic process
0.41	GO:0055085	transmembrane transport
0.39	GO:0048513	animal organ development
0.38	GO:0050852	T cell receptor signaling pathway
0.38	GO:0007568	aging

0.50	GO:0046982	protein heterodimerization activity
0.50	GO:0042803	protein homodimerization activity
0.47	GO:0022803	passive transmembrane transporter activity
0.40	GO:0051400	BH domain binding
0.39	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.35	GO:0016874	ligase activity

0.51	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0016874

sp|Q16549|PCSK7_HUMAN
Proprotein convertase subtilisin/kexin type 7
Search

PCSK7

0.97	Proprotein convertase subtilisin/kexin type 7

0.61	GO:0006508	proteolysis
0.50	GO:0051604	protein maturation
0.44	GO:0048840	otolith development
0.42	GO:0001654	eye development
0.42	GO:0043009	chordate embryonic development
0.42	GO:0007420	brain development
0.35	GO:0042445	hormone metabolic process
0.33	GO:0048899	anterior lateral line development
0.33	GO:0006518	peptide metabolic process
0.33	GO:0048884	neuromast development

0.69

GO:0004252

serine-type endopeptidase activity

0.55	GO:0030173	integral component of Golgi membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005802	trans-Golgi network

0.69

GO:0004252

sp|Q16552|IL17_HUMAN
Interleukin-17A
Search

IL17A

0.96	Viral interleukin-17

0.79	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.65	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.65	GO:2000778	positive regulation of interleukin-6 secretion
0.61	GO:0072537	fibroblast activation
0.60	GO:0032747	positive regulation of interleukin-23 production
0.59	GO:0045672	positive regulation of osteoclast differentiation
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0071347	cellular response to interleukin-1
0.55	GO:0050832	defense response to fungus

0.80	GO:0005125	cytokine activity
0.47	GO:0019955	cytokine binding
0.47	GO:0005126	cytokine receptor binding
0.45	GO:0042803	protein homodimerization activity
0.34	GO:0004386	helicase activity
0.33	GO:0008233	peptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.55	GO:0009897	external side of plasma membrane
0.33	GO:0042555	MCM complex
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005813	centrosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.33

GO:0008233

sp|Q16553|LY6E_HUMAN
Lymphocyte antigen 6E
Search

LY6E

0.88	Lymphocyte antigen 6 family member E

0.67	GO:0048242	epinephrine secretion
0.63	GO:0042415	norepinephrine metabolic process
0.61	GO:0030325	adrenal gland development
0.61	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.61	GO:2000272	negative regulation of receptor activity
0.60	GO:0035265	organ growth
0.60	GO:0095500	acetylcholine receptor signaling pathway
0.58	GO:0001701	in utero embryonic development
0.49	GO:0006501	C-terminal protein lipidation
0.44	GO:0007166	cell surface receptor signaling pathway

0.62	GO:0033130	acetylcholine receptor binding
0.62	GO:0030550	acetylcholine receptor inhibitor activity

0.51	GO:0031225	anchored component of membrane
0.42	GO:0005887	integral component of plasma membrane
0.42	GO:0005576	extracellular region

sp|Q16555|DPYL2_HUMAN
Dihydropyrimidinase-related protein 2
Search

DPYSL2

0.95	Dihydropyrimidinase-related protein 2 isoform B

0.84	GO:0030516	regulation of axon extension
0.81	GO:0007411	axon guidance
0.79	GO:0007420	brain development
0.71	GO:0007010	cytoskeleton organization
0.42	GO:0014049	positive regulation of glutamate secretion
0.41	GO:0001975	response to amphetamine
0.41	GO:0042220	response to cocaine
0.40	GO:0021510	spinal cord development
0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0097480	establishment of synaptic vesicle localization

0.74	GO:0008017	microtubule binding
0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.44	GO:0019901	protein kinase binding
0.38	GO:0042802	identical protein binding

0.48	GO:0005737	cytoplasm
0.45	GO:0043209	myelin sheath
0.45	GO:0043025	neuronal cell body
0.45	GO:0030425	dendrite
0.45	GO:0030424	axon
0.40	GO:0005874	microtubule
0.40	GO:0043679	axon terminus
0.40	GO:0030426	growth cone
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0005886	plasma membrane

0.65

EC:3.5

GO:0016810

sp|Q16557|PSG3_HUMAN
Pregnancy-specific beta-1-glycoprotein 3
Search

0.94	Pregnancy-specific beta-1-glycoprotein 3

0.80	GO:0007565	female pregnancy
0.41	GO:0006952	defense response
0.40	GO:0043317	regulation of cytotoxic T cell degranulation
0.40	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.39	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.39	GO:0043301	negative regulation of leukocyte degranulation
0.39	GO:0016477	cell migration
0.39	GO:0050860	negative regulation of T cell receptor signaling pathway
0.39	GO:0090505	epiboly involved in wound healing
0.38	GO:0050868	negative regulation of T cell activation

0.39	GO:0031005	filamin binding
0.38	GO:1990782	protein tyrosine kinase binding
0.38	GO:0019903	protein phosphatase binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0003779	actin binding

0.51	GO:0005576	extracellular region
0.41	GO:0031982	vesicle
0.39	GO:0042101	T cell receptor complex
0.37	GO:0005911	cell-cell junction
0.37	GO:0009986	cell surface
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0044446	intracellular organelle part
0.33	GO:0044444	cytoplasmic part

sp|Q16558|KCMB1_HUMAN
Calcium-activated potassium channel subunit beta-1
Search

KCNMB1

0.97	Calcium-activated potassium channel beta subunit

0.73	GO:0071805	potassium ion transmembrane transport
0.55	GO:0005513	detection of calcium ion
0.50	GO:0007268	chemical synaptic transmission
0.45	GO:0065009	regulation of molecular function
0.43	GO:1903413	cellular response to bile acid
0.42	GO:0071361	cellular response to ethanol
0.42	GO:0097755	positive regulation of blood vessel diameter
0.41	GO:1901381	positive regulation of potassium ion transmembrane transport
0.41	GO:0071456	cellular response to hypoxia
0.40	GO:0007568	aging

0.84	GO:0015269	calcium-activated potassium channel activity
0.55	GO:0015459	potassium channel regulator activity
0.34	GO:0005515	protein binding

0.50

GO:0008076

voltage-gated potassium channel complex

sp|Q16559|TAL2_HUMAN
T-cell acute lymphocytic leukemia protein 2
Search

TAL2

0.97	T-cell acute lymphocytic leukemia protein 2

0.58	GO:0021794	thalamus development
0.56	GO:0030901	midbrain development
0.55	GO:0035264	multicellular organism growth
0.52	GO:0009791	post-embryonic development
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0021514	ventral spinal cord interneuron differentiation
0.34	GO:0060214	endocardium formation
0.34	GO:0060217	hemangioblast cell differentiation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0060218	hematopoietic stem cell differentiation

0.68	GO:0046983	protein dimerization activity
0.47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0005261	cation channel activity

0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q16560|U1SBP_HUMAN
U11/U12 small nuclear ribonucleoprotein 35 kDa protein
Search

SNRNP35

0.96	Small nuclear ribonucleoprotein U11/U12 subunit 35

0.46	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0006413	translational initiation

0.59

GO:0003723

RNA binding

0.60	GO:0005689	U12-type spliceosomal complex
0.59	GO:0019013	viral nucleocapsid
0.52	GO:0005730	nucleolus
0.49	GO:0071011	precatalytic spliceosome
0.49	GO:0000243	commitment complex
0.35	GO:0034693	U11/U12 snRNP
0.34	GO:0005654	nucleoplasm

sp|Q16563|SYPL1_HUMAN
Synaptophysin-like protein 1
Search

SYPL1

0.90	Synaptophysin-like protein 1 isoform a

0.37	GO:0098916	anterograde trans-synaptic signaling
0.34	GO:0006508	proteolysis

0.34

GO:0004252

serine-type endopeptidase activity

0.82	GO:0008021	synaptic vesicle
0.46	GO:0030141	secretory granule
0.45	GO:0099501	exocytic vesicle membrane
0.43	GO:0031301	integral component of organelle membrane
0.42	GO:0070062	extracellular exosome
0.41	GO:0042470	melanosome
0.36	GO:0005887	integral component of plasma membrane

0.34

GO:0004252

sp|Q16566|KCC4_HUMAN
Calcium/calmodulin-dependent protein kinase type IV
Search

CAMK4

0.95	LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type IV

0.63	GO:0006468	protein phosphorylation
0.57	GO:0043011	myeloid dendritic cell differentiation
0.56	GO:0007616	long-term memory
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0018209	peptidyl-serine modification
0.42	GO:0035556	intracellular signal transduction
0.40	GO:0002372	myeloid dendritic cell cytokine production
0.40	GO:0060216	definitive hemopoiesis
0.39	GO:0002250	adaptive immune response
0.38	GO:0006954	inflammatory response

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005516	calmodulin binding
0.35	GO:0046875	ephrin receptor binding
0.33	GO:0048038	quinone binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0046872	metal ion binding

0.54	GO:0001650	fibrillar center
0.48	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.33

EC:1.6.5.3

GO:0008137

sp|Q16568|CART_HUMAN
Cocaine- and amphetamine-regulated transcript protein
Search

CARTPT

0.97	Cocaine-and amphetamine-regulated transcript

0.86	GO:0032099	negative regulation of appetite
0.86	GO:0008343	adult feeding behavior
0.84	GO:0000186	activation of MAPKK activity
0.82	GO:0001678	cellular glucose homeostasis
0.78	GO:0009267	cellular response to starvation
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0032812	positive regulation of epinephrine secretion
0.62	GO:0051971	positive regulation of transmission of nerve impulse
0.61	GO:0045779	negative regulation of bone resorption
0.60	GO:0045777	positive regulation of blood pressure

0.50

GO:0005184

neuropeptide hormone activity

0.73	GO:0005615	extracellular space
0.56	GO:0030141	secretory granule
0.30	GO:0016020	membrane

sp|Q16570|ACKR1_HUMAN
Atypical chemokine receptor 1
Search

DARC

0.96	Duffy antigen chemokine receptor

0.84	GO:0070098	chemokine-mediated signaling pathway
0.80	GO:0006954	inflammatory response
0.40	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0032642	regulation of chemokine production

0.85	GO:0019956	chemokine binding
0.41	GO:0004930	G-protein coupled receptor activity

0.43	GO:0055037	recycling endosome
0.43	GO:0005769	early endosome
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q16572|VACHT_HUMAN
Vesicular acetylcholine transporter
Search

SLC18A3

0.95	Vesicular acetylcholine transporter

0.57	GO:0006855	drug transmembrane transport
0.51	GO:1901374	acetate ester transport
0.46	GO:0006836	neurotransmitter transport
0.45	GO:0072488	ammonium transmembrane transport
0.45	GO:0015695	organic cation transport
0.36	GO:0015844	monoamine transport
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.34	GO:0001505	regulation of neurotransmitter levels
0.34	GO:0051649	establishment of localization in cell

0.56	GO:0015238	drug transmembrane transporter activity
0.51	GO:1901375	acetate ester transmembrane transporter activity
0.50	GO:0042166	acetylcholine binding
0.46	GO:0015101	organic cation transmembrane transporter activity
0.46	GO:0005326	neurotransmitter transporter activity
0.45	GO:0008519	ammonium transmembrane transporter activity
0.42	GO:0016746	transferase activity, transferring acyl groups
0.36	GO:0008504	monoamine transmembrane transporter activity
0.33	GO:0005515	protein binding

0.49	GO:0030121	AP-1 adaptor complex
0.48	GO:0030122	AP-2 adaptor complex
0.42	GO:0060200	clathrin-sculpted acetylcholine transport vesicle
0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0098793	presynapse
0.38	GO:0044306	neuron projection terminus
0.37	GO:0033267	axon part
0.35	GO:0070382	exocytic vesicle

0.42

GO:0016746

sp|Q16576|RBBP7_HUMAN
Histone-binding protein RBBP7
Search

RBBP7

0.84	RB binding protein 7, chromatin remodeling factor

0.56	GO:0070370	cellular heat acclimation
0.54	GO:0030308	negative regulation of cell growth
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0006335	DNA replication-dependent nucleosome assembly
0.46	GO:0006336	DNA replication-independent nucleosome assembly
0.44	GO:0006338	chromatin remodeling
0.42	GO:0016569	covalent chromatin modification
0.40	GO:0006260	DNA replication
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:0009725	response to hormone

0.45	GO:0042826	histone deacetylase binding
0.43	GO:0003723	RNA binding
0.41	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.34	GO:0031492	nucleosomal DNA binding
0.34	GO:0004407	histone deacetylase activity
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.57	GO:0017053	transcriptional repressor complex
0.56	GO:0034708	methyltransferase complex
0.52	GO:0000785	chromatin
0.51	GO:0031974	membrane-enclosed lumen
0.50	GO:0005829	cytosol
0.49	GO:1904949	ATPase complex
0.48	GO:0033186	CAF-1 complex

0.34

GO:0004407

sp|Q16581|C3AR_HUMAN
C3a anaphylatoxin chemotactic receptor
Search

C3AR1

0.97	Complement component 3a receptor 1

0.85	GO:0002430	complement receptor mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.68	GO:0006935	chemotaxis
0.67	GO:0010759	positive regulation of macrophage chemotaxis
0.66	GO:0090022	regulation of neutrophil chemotaxis
0.66	GO:0071624	positive regulation of granulocyte chemotaxis
0.66	GO:0010575	positive regulation of vascular endothelial growth factor production
0.66	GO:1902624	positive regulation of neutrophil migration
0.63	GO:0045766	positive regulation of angiogenesis
0.63	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.85	GO:0004875	complement receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.54	GO:0001847	opsonin receptor activity
0.38	GO:0001848	complement binding
0.38	GO:0001653	peptide receptor activity
0.34	GO:0042277	peptide binding
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0015464	acetylcholine receptor activity

0.45	GO:0005887	integral component of plasma membrane
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0045177	apical part of cell
0.39	GO:0035579	specific granule membrane
0.39	GO:0035577	azurophil granule membrane
0.37	GO:0045178	basal part of cell
0.34	GO:0005840	ribosome
0.33	GO:0043005	neuron projection
0.33	GO:0009986	cell surface
0.32	GO:0005654	nucleoplasm

sp|Q16584|M3K11_HUMAN
Mitogen-activated protein kinase kinase kinase 11
Search

MAP3K11

0.77	Mitogen-activated protein kinase kinase kinase

0.76	GO:0007256	activation of JNKK activity
0.62	GO:0007257	activation of JUN kinase activity
0.56	GO:0046777	protein autophosphorylation
0.55	GO:0008283	cell proliferation
0.51	GO:0007017	microtubule-based process
0.47	GO:0043065	positive regulation of apoptotic process
0.42	GO:1901216	positive regulation of neuron death
0.41	GO:0043523	regulation of neuron apoptotic process
0.40	GO:0008219	cell death
0.33	GO:0018108	peptidyl-tyrosine phosphorylation

0.77	GO:0004706	JUN kinase kinase kinase activity
0.60	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0042803	protein homodimerization activity
0.43	GO:0031434	mitogen-activated protein kinase kinase binding
0.42	GO:0048365	Rac GTPase binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0004713	protein tyrosine kinase activity

0.55	GO:0005813	centrosome
0.52	GO:0005874	microtubule
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.77

GO:0004706

sp|Q16585|SGCB_HUMAN
Beta-sarcoglycan
Search

SGCB

0.97	Beta-sarcoglycan

0.81	GO:0007517	muscle organ development
0.59	GO:0097084	vascular smooth muscle cell development
0.57	GO:0055013	cardiac muscle cell development
0.56	GO:0048747	muscle fiber development
0.43	GO:0061024	membrane organization

0.85	GO:0016012	sarcoglycan complex
0.60	GO:0042383	sarcolemma
0.38	GO:0005856	cytoskeleton
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0005737	cytoplasm

sp|Q16586|SGCA_HUMAN
Alpha-sarcoglycan
Search

SGCA

0.66	alpha-sarcoglycan precursor

0.49	GO:0003012	muscle system process
0.43	GO:0061024	membrane organization
0.42	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation
0.41	GO:0043403	skeletal muscle tissue regeneration
0.37	GO:0007517	muscle organ development
0.34	GO:0007160	cell-matrix adhesion
0.34	GO:0001822	kidney development
0.34	GO:0014706	striated muscle tissue development
0.33	GO:0007420	brain development
0.33	GO:0006334	nucleosome assembly

0.60	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.85	GO:0016012	sarcoglycan complex
0.57	GO:0042383	sarcolemma
0.54	GO:0045121	membrane raft
0.52	GO:0005911	cell-cell junction
0.49	GO:0032590	dendrite membrane
0.43	GO:0005794	Golgi apparatus
0.39	GO:0005856	cytoskeleton
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0000786	nucleosome
0.32	GO:0005634	nucleus

sp|Q16587|ZNF74_HUMAN
Zinc finger protein 74
Search

ZNF606

0.88	zinc finger protein 74

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:0007275	multicellular organism development
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0006413	translational initiation
0.35	GO:1902679	negative regulation of RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.49	GO:0005634	nucleus
0.44	GO:0015629	actin cytoskeleton
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.35	GO:0015630	microtubule cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q16589|CCNG2_HUMAN
Cyclin-G2
Search

0.73	GO:0051726	regulation of cell cycle
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.34	GO:0006949	syncytium formation
0.33	GO:0007420	brain development
0.33	GO:0043066	negative regulation of apoptotic process
0.33	GO:0071900	regulation of protein serine/threonine kinase activity
0.33	GO:0010243	response to organonitrogen compound
0.32	GO:0006974	cellular response to DNA damage stimulus

0.34	GO:0005515	protein binding
0.33	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity
0.32	GO:0016787	hydrolase activity

0.35	GO:0005634	nucleus
0.33	GO:0043025	neuronal cell body
0.33	GO:0030425	dendrite
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.8.2.8

GO:0015016

sp|Q16594|TAF9_HUMAN
Transcription initiation factor TFIID subunit 9
Search

0.73	TATA-box binding protein associated factor 9

0.69	GO:0006352	DNA-templated transcription, initiation
0.68	GO:0030307	positive regulation of cell growth
0.66	GO:0050821	protein stabilization
0.65	GO:0043066	negative regulation of apoptotic process
0.63	GO:0000122	negative regulation of transcription by RNA polymerase II
0.58	GO:0043966	histone H3 acetylation
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0065004	protein-DNA complex assembly
0.52	GO:0006366	transcription by RNA polymerase II
0.41	GO:0000492	box C/D snoRNP assembly

0.74	GO:0046982	protein heterodimerization activity
0.59	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.56	GO:0004402	histone acetyltransferase activity
0.54	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0008134	transcription factor binding
0.42	GO:0070742	C2H2 zinc finger domain binding
0.41	GO:0051117	ATPase binding
0.41	GO:0002039	p53 binding
0.39	GO:0003713	transcription coactivator activity
0.38	GO:0003743	translation initiation factor activity

0.72	GO:0033276	transcription factor TFTC complex
0.68	GO:0005669	transcription factor TFIID complex
0.54	GO:0000124	SAGA complex
0.42	GO:0000125	PCAF complex
0.42	GO:0070761	pre-snoRNP complex
0.41	GO:0030914	STAGA complex
0.40	GO:0071339	MLL1 complex

0.56

GO:0004402

sp|Q16595|FRDA_HUMAN
Frataxin, mitochondrial
Search

FXN

0.89	Frataxin, mitochondrial

0.74	GO:0016226	iron-sulfur cluster assembly
0.61	GO:0010722	regulation of ferrochelatase activity
0.60	GO:1904231	positive regulation of succinate dehydrogenase activity
0.60	GO:1904234	positive regulation of aconitate hydratase activity
0.60	GO:0018282	metal incorporation into metallo-sulfur cluster
0.58	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.56	GO:0010039	response to iron ion
0.56	GO:0070301	cellular response to hydrogen peroxide
0.56	GO:0016540	protein autoprocessing
0.56	GO:0019230	proprioception

0.79	GO:0004322	ferroxidase activity
0.76	GO:0008199	ferric iron binding
0.60	GO:0034986	iron chaperone activity
0.53	GO:0008198	ferrous iron binding
0.50	GO:0051537	2 iron, 2 sulfur cluster binding
0.38	GO:0016307	phosphatidylinositol phosphate kinase activity
0.35	GO:0005515	protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding

0.59	GO:0005739	mitochondrion
0.48	GO:0005829	cytosol
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0005923	bicellular tight junction
0.34	GO:0044446	intracellular organelle part
0.33	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

0.79

EC:1.16.3.1

GO:0004322

sp|Q16600|ZN239_HUMAN
Zinc finger protein 239
Search

0.64	Zinc finger protein-interacting with ribonucleoprotein K

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.42	GO:0006351	transcription, DNA-templated
0.38	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0070895	negative regulation of transposon integration
0.37	GO:2000773	negative regulation of cellular senescence
0.36	GO:0007040	lysosome organization
0.35	GO:0010507	negative regulation of autophagy
0.35	GO:1902680	positive regulation of RNA biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.37	GO:0042802	identical protein binding
0.36	GO:0003682	chromatin binding
0.32	GO:0008168	methyltransferase activity

0.44	GO:0005634	nucleus
0.39	GO:0019013	viral nucleocapsid
0.37	GO:0005829	cytosol
0.37	GO:0043233	organelle lumen
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0044446	intracellular organelle part

0.32

GO:0008168

sp|Q16602|CALRL_HUMAN
Calcitonin gene-related peptide type 1 receptor
Search

CALCRL

0.97	Calcitonin receptor like receptor

0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.58	GO:0071329	cellular response to sucrose stimulus
0.56	GO:0031623	receptor internalization
0.55	GO:0019933	cAMP-mediated signaling
0.54	GO:0001525	angiogenesis
0.51	GO:0006816	calcium ion transport
0.50	GO:0048661	positive regulation of smooth muscle cell proliferation
0.47	GO:0007507	heart development
0.46	GO:0015031	protein transport

0.85	GO:0004948	calcitonin receptor activity
0.59	GO:1990409	adrenomedullin binding
0.59	GO:0001635	calcitonin gene-related peptide receptor activity
0.59	GO:0001605	adrenomedullin receptor activity
0.49	GO:0008565	protein transporter activity
0.37	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0005515	protein binding

0.59	GO:1990406	CGRP receptor complex
0.59	GO:1903143	adrenomedullin receptor complex
0.53	GO:0005764	lysosome
0.51	GO:0005768	endosome
0.48	GO:0005783	endoplasmic reticulum
0.36	GO:0001669	acrosomal vesicle
0.35	GO:0005929	cilium

sp|Q16609|LPAL2_HUMAN
Putative apolipoprotein(a)-like protein 2
Search

0.68

Plasmin

0.58	GO:0006508	proteolysis
0.57	GO:0042730	fibrinolysis
0.55	GO:0048771	tissue remodeling
0.54	GO:0007596	blood coagulation
0.50	GO:0016477	cell migration
0.48	GO:0021684	cerebellar granular layer formation
0.47	GO:0021533	cell differentiation in hindbrain
0.47	GO:0045445	myoblast differentiation
0.47	GO:0046716	muscle cell cellular homeostasis
0.46	GO:0060707	trophoblast giant cell differentiation

0.65	GO:0004252	serine-type endopeptidase activity
0.45	GO:0004713	protein tyrosine kinase activity
0.44	GO:0034185	apolipoprotein binding
0.44	GO:0019900	kinase binding
0.41	GO:0001968	fibronectin binding
0.40	GO:1904854	proteasome core complex binding
0.40	GO:1990405	protein antigen binding
0.39	GO:0008201	heparin binding
0.38	GO:0004866	endopeptidase inhibitor activity
0.38	GO:0005524	ATP binding

0.50	GO:0005576	extracellular region
0.44	GO:0019897	extrinsic component of plasma membrane
0.40	GO:1990777	lipoprotein particle
0.38	GO:0009897	external side of plasma membrane
0.36	GO:0044218	other organism cell membrane
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0004252

sp|Q16610|ECM1_HUMAN
Extracellular matrix protein 1
Search

ECM1

0.96	Truncated extracellular matrix protein 1

0.71	GO:0030502	negative regulation of bone mineralization
0.70	GO:0002828	regulation of type 2 immune response
0.70	GO:2000404	regulation of T cell migration
0.68	GO:0001938	positive regulation of endothelial cell proliferation
0.67	GO:0045766	positive regulation of angiogenesis
0.64	GO:0006954	inflammatory response
0.61	GO:0010466	negative regulation of peptidase activity
0.61	GO:0007165	signal transduction
0.60	GO:0060761	negative regulation of response to cytokine stimulus
0.60	GO:0001959	regulation of cytokine-mediated signaling pathway

0.71	GO:0005134	interleukin-2 receptor binding
0.69	GO:0043236	laminin binding
0.67	GO:0002020	protease binding
0.66	GO:0008022	protein C-terminus binding
0.38	GO:0004871	signal transducer activity

0.73	GO:0005615	extracellular space
0.60	GO:0031012	extracellular matrix
0.42	GO:0031089	platelet dense granule lumen
0.41	GO:1903561	extracellular vesicle

sp|Q16611|BAK_HUMAN
Bcl-2 homologous antagonist/killer
Search

BAK1

0.97	Pro-apoptotic protein BAKM variant

0.79	GO:0043065	positive regulation of apoptotic process
0.62	GO:0002352	B cell negative selection
0.62	GO:0001836	release of cytochrome c from mitochondria
0.62	GO:0044346	fibroblast apoptotic process
0.61	GO:0048597	post-embryonic camera-type eye morphogenesis
0.61	GO:0010046	response to mycotoxin
0.61	GO:0070242	thymocyte apoptotic process
0.61	GO:0038034	signal transduction in absence of ligand
0.60	GO:0043497	regulation of protein heterodimerization activity
0.60	GO:1902262	apoptotic process involved in blood vessel morphogenesis

0.57	GO:0044325	ion channel binding
0.54	GO:0042803	protein homodimerization activity
0.53	GO:0046982	protein heterodimerization activity
0.43	GO:0051400	BH domain binding
0.40	GO:0031072	heat shock protein binding
0.40	GO:0051087	chaperone binding
0.34	GO:0046872	metal ion binding
0.32	GO:0015267	channel activity

0.63	GO:0097145	BAK complex
0.56	GO:0031307	integral component of mitochondrial outer membrane
0.54	GO:0046930	pore complex
0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005829	cytosol

sp|Q16612|NREP_HUMAN
Neuronal regeneration-related protein
Search

NREP

0.97	Neuronal regeneration-related protein isoform a

0.72	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.57	GO:0031103	axon regeneration
0.53	GO:0045664	regulation of neuron differentiation

0.47

GO:0005515

protein binding

0.45	GO:0005737	cytoplasm
0.44	GO:0005634	nucleus

sp|Q16613|SNAT_HUMAN
Serotonin N-acetyltransferase
Search

AANAT

0.94	Arylalkylamine-N-acetyl-transferase

0.63	GO:0030187	melatonin biosynthetic process
0.59	GO:0071320	cellular response to cAMP
0.58	GO:0007623	circadian rhythm
0.55	GO:0006474	N-terminal protein amino acid acetylation
0.46	GO:0009416	response to light stimulus
0.41	GO:0051412	response to corticosterone
0.40	GO:0034695	response to prostaglandin E
0.40	GO:0010043	response to zinc ion
0.39	GO:0051592	response to calcium ion
0.39	GO:0032868	response to insulin

0.69	GO:0004059	aralkylamine N-acetyltransferase activity
0.57	GO:0004060	arylamine N-acetyltransferase activity
0.40	GO:0071889	14-3-3 protein binding

0.55	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005829	cytosol

0.69

EC:2.3.1.87

GO:0004059

sp|Q16617|NKG7_HUMAN
Protein NKG7
Search

NKG7

0.97	Natural killer cell granule protein 7

0.30

GO:0044425

membrane part

sp|Q16619|CTF1_HUMAN
Cardiotrophin-1
Search

CTF1

0.97	Cardiotrophin-1

0.84	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.76	GO:0048666	neuron development
0.63	GO:0010469	regulation of receptor activity
0.60	GO:0007166	cell surface receptor signaling pathway
0.43	GO:0007517	muscle organ development
0.42	GO:0008283	cell proliferation
0.42	GO:0008284	positive regulation of cell proliferation
0.42	GO:0071345	cellular response to cytokine stimulus
0.41	GO:0007267	cell-cell signaling
0.40	GO:0006955	immune response

0.66	GO:0005125	cytokine activity
0.58	GO:0005146	leukemia inhibitory factor receptor binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0003677	DNA binding

0.55

GO:0005576

extracellular region

sp|Q16620|NTRK2_HUMAN
BDNF/NT-3 growth factors receptor
Search

NTRK2

0.65	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.78	GO:0038179	neurotrophin signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0099538	synaptic signaling via neuropeptide
0.60	GO:0099550	trans-synaptic signaling, modulating synaptic transmission
0.59	GO:0014047	glutamate secretion
0.59	GO:0046548	retinal rod cell development
0.59	GO:0010975	regulation of neuron projection development
0.58	GO:2000811	negative regulation of anoikis
0.58	GO:0048935	peripheral nervous system neuron development

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.80	GO:0005030	neurotrophin receptor activity
0.61	GO:0048403	brain-derived neurotrophic factor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.46	GO:0022832	voltage-gated channel activity
0.45	GO:0022839	ion gated channel activity
0.45	GO:0008381	mechanosensitive ion channel activity

0.66	GO:0005887	integral component of plasma membrane
0.57	GO:0043195	terminal bouton
0.55	GO:0014069	postsynaptic density
0.54	GO:0005769	early endosome
0.53	GO:0045211	postsynaptic membrane
0.52	GO:0043235	receptor complex
0.48	GO:0005829	cytosol
0.35	GO:0044297	cell body

0.80

EC:2.7.10.1

GO:0004714

sp|Q16621|NFE2_HUMAN
Transcription factor NF-E2 45 kDa subunit
Search

NFE2

0.96	Nuclear factor, erythroid-derived 2 45 kDa subunit

0.64	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0034599	cellular response to oxidative stress
0.56	GO:0006351	transcription, DNA-templated
0.50	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:1903786	regulation of glutathione biosynthetic process
0.45	GO:0071499	cellular response to laminar fluid shear stress
0.44	GO:0036499	PERK-mediated unfolded protein response
0.44	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.44	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.44	GO:1901032	negative regulation of response to reactive oxygen species

0.62	GO:0050699	WW domain binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0047485	protein N-terminus binding
0.60	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.43	GO:0035326	enhancer binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0046982	protein heterodimerization activity
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0001221	transcription cofactor binding

0.61	GO:0005634	nucleus
0.55	GO:0032993	protein-DNA complex
0.43	GO:0005737	cytoplasm
0.42	GO:0005813	centrosome
0.41	GO:0070013	intracellular organelle lumen
0.40	GO:0000785	chromatin
0.39	GO:0012505	endomembrane system
0.39	GO:0005667	transcription factor complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q16623|STX1A_HUMAN
Syntaxin-1A
Search

STX1A

0.74	Syntaxin-1A isoform A

0.77	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.61	GO:0001956	positive regulation of neurotransmitter secretion
0.61	GO:2000463	positive regulation of excitatory postsynaptic potential
0.60	GO:1902803	regulation of synaptic vesicle transport
0.60	GO:0098693	regulation of synaptic vesicle cycle
0.55	GO:0097480	establishment of synaptic vesicle localization
0.55	GO:0099504	synaptic vesicle cycle

0.80	GO:0005484	SNAP receptor activity
0.76	GO:0000149	SNARE binding
0.55	GO:0019900	kinase binding
0.54	GO:0019869	chloride channel inhibitor activity
0.53	GO:0019855	calcium channel inhibitor activity
0.46	GO:0017022	myosin binding
0.45	GO:0005102	receptor binding
0.41	GO:0043008	ATP-dependent protein binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0048306	calcium-dependent protein binding

0.57	GO:0098793	presynapse
0.57	GO:0031201	SNARE complex
0.56	GO:0030424	axon
0.55	GO:0070382	exocytic vesicle
0.49	GO:0030658	transport vesicle membrane
0.49	GO:0031965	nuclear membrane
0.45	GO:0005887	integral component of plasma membrane
0.41	GO:0097060	synaptic membrane
0.40	GO:0034705	potassium channel complex
0.40	GO:0042641	actomyosin

sp|Q16625|OCLN_HUMAN
Occludin
Search

OCLN

0.95	Occludin antigen

0.85	GO:0070830	bicellular tight junction assembly
0.42	GO:0070673	response to interleukin-18
0.41	GO:0071356	cellular response to tumor necrosis factor
0.36	GO:2000810	regulation of bicellular tight junction assembly
0.35	GO:0007605	sensory perception of sound
0.34	GO:0006461	protein complex assembly
0.34	GO:0006414	translational elongation
0.34	GO:0032259	methylation

0.54	GO:0019904	protein domain specific binding
0.36	GO:0008119	thiopurine S-methyltransferase activity
0.34	GO:0003746	translation elongation factor activity

0.79	GO:0005923	bicellular tight junction
0.61	GO:0016327	apicolateral plasma membrane
0.57	GO:0016324	apical plasma membrane
0.57	GO:0030139	endocytic vesicle
0.41	GO:0016328	lateral plasma membrane
0.37	GO:0009986	cell surface
0.35	GO:0061689	tricellular tight junction
0.30	GO:0016021	integral component of membrane

0.36

EC:2.1.1.67

GO:0008119

sp|Q16626|MEA1_HUMAN
Male-enhanced antigen 1
Search

MEA1

0.97	Male-enhanced antigen 1

0.80	GO:0007283	spermatogenesis
0.41	GO:0030154	cell differentiation
0.41	GO:0007275	multicellular organism development
0.36	GO:0007548	sex differentiation
0.33	GO:0022900	electron transport chain

0.34	GO:0005515	protein binding
0.33	GO:0020037	heme binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0046872	metal ion binding

0.41

GO:0005737

cytoplasm

sp|Q16627|CCL14_HUMAN
C-C motif chemokine 14
Search

CCL14

0.74	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.67	GO:0010469	regulation of receptor activity
0.51	GO:0071674	mononuclear cell migration
0.50	GO:0072676	lymphocyte migration
0.50	GO:0097529	myeloid leukocyte migration
0.50	GO:0071347	cellular response to interleukin-1
0.49	GO:0071356	cellular response to tumor necrosis factor
0.49	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.49	GO:0070098	chemokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.51	GO:0048020	CCR chemokine receptor binding
0.39	GO:0042056	chemoattractant activity
0.39	GO:0004698	calcium-dependent protein kinase C activity
0.38	GO:0016004	phospholipase activator activity

0.66	GO:0005576	extracellular region
0.35	GO:0005829	cytosol

0.39

GO:0004698

sp|Q16629|SRSF7_HUMAN
Serine/arginine-rich splicing factor 7
Search

SRSF7

0.92	Serine and arginine rich splicing factor 7

0.53	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.51	GO:1990823	response to leukemia inhibitory factor
0.48	GO:0071345	cellular response to cytokine stimulus
0.47	GO:0008380	RNA splicing
0.37	GO:0051028	mRNA transport
0.37	GO:0006397	mRNA processing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing
0.34	GO:0006405	RNA export from nucleus

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.48	GO:0019904	protein domain specific binding

0.46	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0019013	viral nucleocapsid
0.33	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex

sp|Q16630|CPSF6_HUMAN
Cleavage and polyadenylation specificity factor subunit 6
Search

CPSF6

0.95	Cleavage and polyadenylation specificity factor subunit 6

0.58	GO:0046833	positive regulation of RNA export from nucleus
0.56	GO:0051290	protein heterotetramerization
0.56	GO:0098789	pre-mRNA cleavage required for polyadenylation
0.53	GO:0006378	mRNA polyadenylation
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0009059	macromolecule biosynthetic process

0.58	GO:1990448	exon-exon junction complex binding
0.58	GO:0003723	RNA binding
0.51	GO:0043023	ribosomal large subunit binding
0.34	GO:0003735	structural constituent of ribosome

0.80	GO:0005849	mRNA cleavage factor complex
0.58	GO:0035061	interchromatin granule
0.58	GO:0005726	perichromatin fibrils
0.57	GO:0042382	paraspeckles
0.53	GO:0016607	nuclear speck
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q16633|OBF1_HUMAN
POU domain class 2-associating factor 1
Search

POU2AF1

0.97	POU domain class 2-associating factor

0.76	GO:0006366	transcription by RNA polymerase II
0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0006959	humoral immune response

0.85	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.85	GO:0001105	RNA polymerase II transcription coactivator activity
0.40	GO:0005515	protein binding

0.77	GO:0090575	RNA polymerase II transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q16635|TAZ_HUMAN
Tafazzin
Search

TAZ

0.76	Tafazzin (Predicted)

0.67	GO:0006644	phospholipid metabolic process
0.58	GO:0007507	heart development
0.58	GO:0007007	inner mitochondrial membrane organization
0.57	GO:0060048	cardiac muscle contraction
0.56	GO:0032981	mitochondrial respiratory chain complex I assembly
0.56	GO:0007519	skeletal muscle tissue development
0.54	GO:0030097	hemopoiesis
0.52	GO:0046486	glycerolipid metabolic process
0.50	GO:0042775	mitochondrial ATP synthesis coupled electron transport
0.47	GO:0008610	lipid biosynthetic process

0.63

GO:0016746

transferase activity, transferring acyl groups

0.48	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.45	GO:0005634	nucleus
0.41	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.63

GO:0016746

sp|Q16637|SMN_HUMAN
Survival motor neuron protein
Search

SMN1

0.85	Survival of motor neuron

0.69	GO:0006397	mRNA processing
0.50	GO:0007399	nervous system development
0.49	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.49	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.48	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.48	GO:0000904	cell morphogenesis involved in differentiation
0.48	GO:0051960	regulation of nervous system development
0.48	GO:0060284	regulation of cell development
0.48	GO:0007019	microtubule depolymerization
0.47	GO:0120036	plasma membrane bounded cell projection organization

0.59	GO:0003723	RNA binding
0.39	GO:0042802	identical protein binding
0.37	GO:0017134	fibroblast growth factor binding

0.61	GO:0005634	nucleus
0.50	GO:0032797	SMN complex
0.50	GO:0043204	perikaryon
0.50	GO:0034719	SMN-Sm protein complex
0.49	GO:0030018	Z disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.46	GO:0043005	neuron projection
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0005829	cytosol
0.41	GO:0044446	intracellular organelle part

sp|Q16643|DREB_HUMAN
Drebrin
Search

DBN1

0.97

Drebrin E

0.75	GO:0007015	actin filament organization
0.63	GO:0010643	cell communication by chemical coupling
0.61	GO:0010644	cell communication by electrical coupling
0.58	GO:0061351	neural precursor cell proliferation
0.55	GO:0032507	maintenance of protein location in cell
0.53	GO:0048699	generation of neurons
0.38	GO:0050773	regulation of dendrite development
0.38	GO:0050804	modulation of chemical synaptic transmission
0.36	GO:1904113	negative regulation of muscle filament sliding
0.36	GO:0090327	negative regulation of locomotion involved in locomotory behavior

0.74	GO:0003779	actin binding
0.55	GO:0045296	cadherin binding
0.41	GO:0005522	profilin binding
0.34	GO:0046872	metal ion binding
0.34	GO:0032403	protein complex binding
0.32	GO:0008017	microtubule binding
0.32	GO:0004721	phosphoprotein phosphatase activity
0.31	GO:0004222	metalloendopeptidase activity

0.58	GO:0030426	growth cone
0.56	GO:0005921	gap junction
0.52	GO:0015629	actin cytoskeleton
0.43	GO:0005886	plasma membrane
0.39	GO:0005938	cell cortex
0.38	GO:0030425	dendrite
0.36	GO:0044430	cytoskeletal part
0.36	GO:0044308	axonal spine
0.35	GO:0060076	excitatory synapse
0.35	GO:0030175	filopodium

0.32

GO:0004721

sp|Q16644|MAPK3_HUMAN
MAP kinase-activated protein kinase 3
Search

MAPKAPK3

0.96	Mitogen-activated protein kinase-activated protein kinase 3

0.61	GO:0006468	protein phosphorylation
0.60	GO:0044351	macropinocytosis
0.57	GO:0018209	peptidyl-serine modification
0.55	GO:0002224	toll-like receptor signaling pathway
0.55	GO:0032496	response to lipopolysaccharide
0.55	GO:0034097	response to cytokine
0.46	GO:0007166	cell surface receptor signaling pathway
0.43	GO:0035556	intracellular signal transduction
0.42	GO:0070935	3'-UTR-mediated mRNA stabilization
0.42	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process

0.65	GO:0004674	protein serine/threonine kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0051019	mitogen-activated protein kinase binding
0.50	GO:0010857	calcium-dependent protein kinase activity
0.47	GO:0005516	calmodulin binding
0.42	GO:0004871	signal transducer activity
0.35	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.34	GO:0008276	protein methyltransferase activity

0.51	GO:0005654	nucleoplasm
0.40	GO:0005813	centrosome
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.65

GO:0004674

sp|Q16647|PTGIS_HUMAN
Prostacyclin synthase
Search

PTGIS

0.96	Prostacyclin synthase

0.80	GO:0046457	prostanoid biosynthetic process
0.79	GO:0006693	prostaglandin metabolic process
0.60	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.59	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.59	GO:1900119	positive regulation of execution phase of apoptosis
0.58	GO:0071354	cellular response to interleukin-6
0.56	GO:0071347	cellular response to interleukin-1
0.56	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.56	GO:0050728	negative regulation of inflammatory response
0.56	GO:0071456	cellular response to hypoxia

0.84	GO:0008116	prostaglandin-I synthase activity
0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0005515	protein binding

0.66	GO:0005789	endoplasmic reticulum membrane
0.56	GO:0005901	caveola
0.46	GO:0005615	extracellular space
0.45	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.84	EC:5.3.99.4	GO:0008116
0.84	KEGG:R02267	GO:0008116

sp|Q16649|NFIL3_HUMAN
Nuclear factor interleukin-3-regulated protein
Search

NFIL3

0.97	Interleukin 3 regulated nuclear factor

0.81	GO:0007623	circadian rhythm
0.74	GO:0006366	transcription by RNA polymerase II
0.73	GO:0006955	immune response
0.61	GO:0071353	cellular response to interleukin-4
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0051253	negative regulation of RNA metabolic process
0.53	GO:0010558	negative regulation of macromolecule biosynthetic process
0.53	GO:0031327	negative regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0003714	transcription corepressor activity
0.35	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

sp|Q16650|TBR1_HUMAN
T-box brain protein 1
Search

TBR1

0.67	T-box transcription factor Eomesodermin

0.60	GO:0021764	amygdala development
0.60	GO:0001661	conditioned taste aversion
0.60	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain
0.59	GO:0010092	specification of animal organ identity
0.58	GO:1902667	regulation of axon guidance
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0030902	hindbrain development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0001102	RNA polymerase II activating transcription factor binding
0.39	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.39	GO:0019901	protein kinase binding
0.38	GO:0003682	chromatin binding
0.35	GO:0005452	inorganic anion exchanger activity

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q16651|PRSS8_HUMAN
Prostasin
Search

PRSS8

0.41	Serine protease

0.61	GO:0006508	proteolysis
0.48	GO:0010765	positive regulation of sodium ion transport
0.43	GO:0030216	keratinocyte differentiation
0.42	GO:0065009	regulation of molecular function
0.42	GO:0060672	epithelial cell morphogenesis involved in placental branching
0.40	GO:0001843	neural tube closure
0.39	GO:0070633	transepithelial transport
0.37	GO:0033993	response to lipid
0.37	GO:1901700	response to oxygen-containing compound
0.37	GO:0097327	response to antineoplastic agent

0.69	GO:0004252	serine-type endopeptidase activity
0.49	GO:0017080	sodium channel regulator activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0008201	heparin binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.32	GO:0046914	transition metal ion binding

0.49	GO:0046658	anchored component of plasma membrane
0.49	GO:0019897	extrinsic component of plasma membrane
0.41	GO:0005576	extracellular region
0.37	GO:0045121	membrane raft
0.37	GO:0031982	vesicle
0.36	GO:0016323	basolateral plasma membrane
0.33	GO:0005737	cytoplasm
0.33	GO:0005887	integral component of plasma membrane

0.69

GO:0004252

sp|Q16653|MOG_HUMAN
Myelin-oligodendrocyte glycoprotein
Search

MOG

0.97	myelin-oligodendrocyte glycoprotein isoform X1

0.59	GO:0007155	cell adhesion
0.37	GO:0032502	developmental process
0.37	GO:0051593	response to folic acid
0.36	GO:0032501	multicellular organismal process
0.35	GO:0033993	response to lipid
0.34	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.34	GO:0044409	entry into host
0.34	GO:0019058	viral life cycle
0.34	GO:0050863	regulation of T cell activation
0.33	GO:0045621	positive regulation of lymphocyte differentiation

0.37	GO:0104005	hijacked molecular function
0.34	GO:0042608	T cell receptor binding

0.38	GO:0043209	myelin sheath
0.36	GO:0045121	membrane raft
0.35	GO:0009986	cell surface
0.34	GO:0071944	cell periphery
0.30	GO:0016021	integral component of membrane

sp|Q16654|PDK4_HUMAN
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
Search

PDK4

0.97	Pyruvate dehydrogenase kinase isozyme 4

0.72	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.67	GO:0008286	insulin receptor signaling pathway
0.65	GO:0010906	regulation of glucose metabolic process
0.63	GO:0042593	glucose homeostasis
0.63	GO:2000811	negative regulation of anoikis
0.62	GO:0071398	cellular response to fatty acid
0.62	GO:0046320	regulation of fatty acid oxidation
0.62	GO:0006885	regulation of pH
0.62	GO:0045124	regulation of bone resorption
0.61	GO:0031669	cellular response to nutrient levels

0.59	GO:0016301	kinase activity
0.51	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.48	GO:0140096	catalytic activity, acting on a protein
0.46	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0042803	protein homodimerization activity
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032403	protein complex binding
0.34	GO:0046982	protein heterodimerization activity

0.51	GO:0044429	mitochondrial part
0.48	GO:0045254	pyruvate dehydrogenase complex
0.47	GO:0019866	organelle inner membrane
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0005829	cytosol
0.43	GO:0044428	nuclear part

0.51

GO:0016773

sp|Q16655|MAR1_HUMAN
Melanoma antigen recognized by T-cells 1
Search

MLANA

0.97	Melanoma antigen recognized by T-cells 1

0.36

GO:0005515

protein binding

0.85	GO:0042470	melanosome
0.67	GO:0005802	trans-Golgi network
0.62	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005887	integral component of plasma membrane

sp|Q16656|NRF1_HUMAN
Nuclear respiratory factor 1
Search

NRF1

0.97	LOW QUALITY PROTEIN: nuclear respiratory factor 1

0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0014823	response to activity
0.49	GO:0045494	photoreceptor cell maintenance
0.49	GO:0003407	neural retina development
0.48	GO:0070417	cellular response to cold
0.38	GO:0007005	mitochondrion organization
0.34	GO:0006091	generation of precursor metabolites and energy

0.80	GO:0001046	core promoter sequence-specific DNA binding
0.72	GO:0042803	protein homodimerization activity
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.36	GO:0005667	transcription factor complex

sp|Q16658|FSCN1_HUMAN
Fascin
Search

0.92	Fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) b (Fragment)

0.75	GO:0007015	actin filament organization
0.73	GO:0016477	cell migration
0.49	GO:1900107	regulation of nodal signaling pathway
0.49	GO:0007163	establishment or maintenance of cell polarity
0.48	GO:0009653	anatomical structure morphogenesis
0.48	GO:0048485	sympathetic nervous system development
0.47	GO:0007492	endoderm development
0.47	GO:0014032	neural crest cell development
0.47	GO:1904888	cranial skeletal system development
0.46	GO:0048706	embryonic skeletal system development

0.80	GO:0030674	protein binding, bridging
0.78	GO:0051015	actin filament binding
0.41	GO:0045296	cadherin binding
0.35	GO:0008144	drug binding
0.30	GO:1901363	heterocyclic compound binding
0.30	GO:0097159	organic cyclic compound binding

0.64	GO:0005856	cytoskeleton
0.47	GO:0005737	cytoplasm
0.45	GO:0005902	microvillus
0.45	GO:0030175	filopodium
0.45	GO:0030426	growth cone
0.44	GO:0001726	ruffle
0.44	GO:0030027	lamellipodium
0.44	GO:0099512	supramolecular fiber
0.44	GO:0044393	microspike
0.44	GO:0031253	cell projection membrane

sp|Q16659|MK06_HUMAN
Mitogen-activated protein kinase 6
Search

MAPK6

0.97	Mitogen-activated protein kinase 6

0.79	GO:0000165	MAPK cascade
0.52	GO:0060999	positive regulation of dendritic spine development
0.45	GO:0071310	cellular response to organic substance
0.39	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0007049	cell cycle

0.81	GO:0004707	MAP kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0019901	protein kinase binding
0.48	GO:0046982	protein heterodimerization activity
0.36	GO:0042803	protein homodimerization activity

0.50	GO:0032156	septin cytoskeleton
0.47	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|Q16661|GUC2B_HUMAN
Guanylate cyclase activator 2B
Search

GUCA2B

0.97	Guanylate cyclase activator 2B

0.86	GO:0031284	positive regulation of guanylate cyclase activity
0.76	GO:0045776	negative regulation of blood pressure
0.76	GO:0007588	excretion
0.75	GO:0007589	body fluid secretion
0.72	GO:0006182	cGMP biosynthetic process
0.40	GO:0007586	digestion
0.38	GO:0030104	water homeostasis
0.36	GO:0050801	ion homeostasis

0.86	GO:0010853	cyclase activator activity
0.86	GO:0030249	guanylate cyclase regulator activity
0.75	GO:0008047	enzyme activator activity

0.74	GO:0001750	photoreceptor outer segment
0.66	GO:0005576	extracellular region
0.39	GO:0031982	vesicle

sp|Q16663|CCL15_HUMAN
C-C motif chemokine 15
Search

0.60	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.57	GO:0097529	myeloid leukocyte migration
0.56	GO:0071674	mononuclear cell migration
0.56	GO:0072676	lymphocyte migration
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.53	GO:0071347	cellular response to interleukin-1
0.53	GO:0006954	inflammatory response
0.53	GO:0071356	cellular response to tumor necrosis factor

0.84	GO:0008009	chemokine activity
0.59	GO:0048020	CCR chemokine receptor binding
0.46	GO:0042056	chemoattractant activity
0.46	GO:0004698	calcium-dependent protein kinase C activity
0.45	GO:0016004	phospholipase activator activity
0.41	GO:0008201	heparin binding
0.35	GO:0042802	identical protein binding
0.34	GO:0045236	CXCR chemokine receptor binding
0.33	GO:0003735	structural constituent of ribosome

0.70	GO:0005615	extracellular space
0.40	GO:0005829	cytosol
0.33	GO:0015934	large ribosomal subunit
0.32	GO:0043234	protein complex

0.46

GO:0004698

sp|Q16665|HIF1A_HUMAN
Hypoxia-inducible factor 1-alpha
Search

HIF1A

0.89	Hypoxia inducible factor 1 alpha subunit

0.61	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.61	GO:0051541	elastin metabolic process
0.60	GO:0060574	intestinal epithelial cell maturation
0.60	GO:0021502	neural fold elevation formation
0.60	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.60	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway
0.60	GO:0032364	oxygen homeostasis
0.60	GO:0019896	axonal transport of mitochondrion
0.60	GO:0001922	B-1 B cell homeostasis
0.60	GO:0010573	vascular endothelial growth factor production

0.66	GO:0046983	protein dimerization activity
0.62	GO:0035035	histone acetyltransferase binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0070888	E-box binding
0.57	GO:0051879	Hsp90 protein binding
0.56	GO:0042826	histone deacetylase binding
0.56	GO:0002039	p53 binding
0.55	GO:0035257	nuclear hormone receptor binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.58	GO:1904115	axon cytoplasm
0.54	GO:0031514	motile cilium
0.51	GO:0005667	transcription factor complex
0.50	GO:0070013	intracellular organelle lumen
0.49	GO:0005829	cytosol
0.45	GO:0044446	intracellular organelle part

sp|Q16666|IF16_HUMAN
Gamma-interferon-inducible protein 16
Search

0.10	Gamma-interferon-inducible protein 16

0.71	GO:0035458	cellular response to interferon-beta
0.64	GO:0070269	pyroptosis
0.64	GO:0050702	interleukin-1 beta secretion
0.62	GO:0050718	positive regulation of interleukin-1 beta secretion
0.62	GO:0032461	positive regulation of protein oligomerization
0.62	GO:0002230	positive regulation of defense response to virus by host
0.60	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.60	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.60	GO:0002253	activation of immune response
0.59	GO:2001056	positive regulation of cysteine-type endopeptidase activity

0.65	GO:0042802	identical protein binding
0.64	GO:0003690	double-stranded DNA binding
0.62	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.62	GO:0001047	core promoter binding
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0008134	transcription factor binding
0.51	GO:0043565	sequence-specific DNA binding
0.42	GO:0003712	transcription cofactor activity
0.30	GO:0003723	RNA binding

0.66	GO:0031981	nuclear lumen
0.64	GO:0005829	cytosol
0.52	GO:0043232	intracellular non-membrane-bounded organelle
0.48	GO:0005739	mitochondrion
0.46	GO:0043234	protein complex
0.46	GO:0042405	nuclear inclusion body
0.30	GO:0016020	membrane

sp|Q16667|CDKN3_HUMAN
Cyclin-dependent kinase inhibitor 3
Search

CDKN3

0.97	Mutant cyclin-dependent kinase associated protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:0007050	cell cycle arrest
0.49	GO:0016310	phosphorylation
0.49	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.35	GO:0008285	negative regulation of cell proliferation
0.34	GO:0006974	cellular response to DNA damage stimulus

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0004722	protein serine/threonine phosphatase activity
0.51	GO:0016301	kinase activity
0.48	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.35	GO:0005515	protein binding

0.65	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.75

GO:0004725

sp|Q16670|ZSC26_HUMAN
Zinc finger and SCAN domain-containing protein 26
Search

0.44	Zinc finger with KRAB and SCAN domains 3

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0006351	transcription, DNA-templated
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0007219	Notch signaling pathway
0.32	GO:0006898	receptor-mediated endocytosis

0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0046872	metal ion binding
0.49	GO:0003676	nucleic acid binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0003682	chromatin binding
0.33	GO:0005044	scavenger receptor activity

0.60	GO:0005634	nucleus
0.46	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.40	GO:0005856	cytoskeleton
0.37	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q16671|AMHR2_HUMAN
Anti-Muellerian hormone type-2 receptor
Search

AMHR2

0.54	Receptor protein serine/threonine kinase

0.79	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.73	GO:1990262	anti-Mullerian hormone signaling pathway
0.73	GO:1902612	regulation of anti-Mullerian hormone signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.63	GO:0007548	sex differentiation
0.58	GO:0009968	negative regulation of signal transduction
0.43	GO:0071560	cellular response to transforming growth factor beta stimulus
0.42	GO:0048608	reproductive structure development
0.40	GO:0048513	animal organ development
0.39	GO:0060033	anatomical structure regression

0.78	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.76	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.73	GO:1990272	anti-Mullerian hormone receptor activity
0.66	GO:0042562	hormone binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.33	GO:0004713	protein tyrosine kinase activity

0.39	GO:0005887	integral component of plasma membrane
0.35	GO:0043235	receptor complex
0.32	GO:0005882	intermediate filament

0.78

GO:0004702

sp|Q16674|MIA_HUMAN
Melanoma-derived growth regulatory protein
Search

0.92	melanoma-derived growth regulatory protein isoform X2

0.69	GO:0010469	regulation of receptor activity
0.60	GO:0007160	cell-matrix adhesion
0.59	GO:0030198	extracellular matrix organization
0.53	GO:0008283	cell proliferation

0.71	GO:0008083	growth factor activity
0.43	GO:0003924	GTPase activity
0.42	GO:0001883	purine nucleoside binding
0.42	GO:0019001	guanyl nucleotide binding
0.42	GO:0032549	ribonucleoside binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q16676|FOXD1_HUMAN
Forkhead box protein D1
Search

0.93	Winged helix protein CWH-1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0051254	positive regulation of RNA metabolic process
0.52	GO:0030154	cell differentiation
0.51	GO:0009653	anatomical structure morphogenesis
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process
0.48	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.45	GO:0008301	DNA binding, bending
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.43	GO:0000785	chromatin
0.41	GO:0070013	intracellular organelle lumen
0.34	GO:0005667	transcription factor complex

sp|Q16678|CP1B1_HUMAN
Cytochrome P450 1B1
Search

CYP1B1

0.97	Cytochrome P450 family 1 subfamily B polypeptide 1

0.79	GO:0042572	retinol metabolic process
0.72	GO:0006805	xenobiotic metabolic process
0.71	GO:0008202	steroid metabolic process
0.60	GO:0002930	trabecular meshwork development
0.59	GO:0071603	endothelial cell-cell adhesion
0.59	GO:0061304	retinal blood vessel morphogenesis
0.59	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.58	GO:0042574	retinal metabolic process
0.58	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.57	GO:0010575	positive regulation of vascular endothelial growth factor production

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.62	GO:0005506	iron ion binding
0.35	GO:0019825	oxygen binding

0.44	GO:0005739	mitochondrion
0.44	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q16690|DUS5_HUMAN
Dual specificity protein phosphatase 5
Search

DUSP5

0.71	Dual specificity protein phosphatase

0.84	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.60	GO:0035970	peptidyl-threonine dephosphorylation
0.50	GO:0001706	endoderm formation
0.38	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.37	GO:0042981	regulation of apoptotic process
0.36	GO:0071850	mitotic cell cycle arrest
0.36	GO:0045906	negative regulation of vasoconstriction
0.36	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.36	GO:0051447	negative regulation of meiotic cell cycle

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.40	GO:0008330	protein tyrosine/threonine phosphatase activity
0.39	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.34	GO:0005515	protein binding
0.32	GO:0016301	kinase activity

0.40	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.85

GO:0017017

sp|Q16695|H31T_HUMAN
Histone H3.1t
Search

0.10

Histone 3

0.49	GO:0032460	negative regulation of protein oligomerization
0.49	GO:0051290	protein heterotetramerization
0.48	GO:0006334	nucleosome assembly
0.35	GO:0016233	telomere capping
0.35	GO:0006303	double-strand break repair via nonhomologous end joining
0.35	GO:0051382	kinetochore assembly
0.34	GO:0000070	mitotic sister chromatid segregation
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.42	GO:0031491	nucleosome binding

0.74	GO:0000786	nucleosome
0.60	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.36	GO:0098687	chromosomal region
0.35	GO:0070062	extracellular exosome
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q16696|CP2AD_HUMAN
Cytochrome P450 2A13
Search

0.97	Felis catus cytochrome P450, family 2, subfamily A, polypeptide 13

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0019373	epoxygenase P450 pathway

0.77	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0008392	arachidonic acid epoxygenase activity
0.45	GO:0008395	steroid hydroxylase activity

0.77

EC:1.14.14

GO:0016712

sp|Q16698|DECR_HUMAN
2,4-dienoyl-CoA reductase, mitochondrial
Search

DECR1

0.48	2,4-dienoyl-CoA reductase, mitochondrial

0.82	GO:0051289	protein homotetramerization
0.74	GO:0006635	fatty acid beta-oxidation

0.83	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity
0.76	GO:0070402	NADPH binding
0.37	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.59	GO:0005739	mitochondrion
0.43	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.3.1.34

GO:0008670

sp|Q16706|MA2A1_HUMAN
Alpha-mannosidase 2
Search

MAN2A1

0.47	Alpha-mannosidase

0.81	GO:0006013	mannose metabolic process
0.57	GO:0006491	N-glycan processing
0.56	GO:0007585	respiratory gaseous exchange
0.56	GO:0048286	lung alveolus development
0.55	GO:0060042	retina morphogenesis in camera-type eye
0.55	GO:0001889	liver development
0.53	GO:0050769	positive regulation of neurogenesis
0.53	GO:0007033	vacuole organization
0.52	GO:0001701	in utero embryonic development
0.51	GO:0006517	protein deglycosylation

0.79	GO:0004559	alpha-mannosidase activity
0.70	GO:0030246	carbohydrate binding
0.53	GO:0046872	metal ion binding
0.52	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds

0.58	GO:0005797	Golgi medial cisterna
0.54	GO:0005801	cis-Golgi network
0.52	GO:0000139	Golgi membrane
0.50	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.79

EC:3.2.1.24

GO:0004559

sp|Q16718|NDUA5_HUMAN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Search

NDUFA5

0.79	NADH:ubiquinone oxidoreductase subunit A5

0.74	GO:0032981	mitochondrial respiratory chain complex I assembly
0.67	GO:0022904	respiratory electron transport chain

0.67

GO:0016651

oxidoreductase activity, acting on NAD(P)H

0.71

GO:0005747

mitochondrial respiratory chain complex I

0.67

EC:1.6

GO:0016651

sp|Q16719|KYNU_HUMAN
Kynureninase
Search

KYNU

0.62	Kynureninase

0.76	GO:0006569	tryptophan catabolic process
0.72	GO:0097053	L-kynurenine catabolic process
0.72	GO:0009435	NAD biosynthetic process
0.71	GO:0043420	anthranilate metabolic process
0.69	GO:0019805	quinolinate biosynthetic process
0.60	GO:0034516	response to vitamin B6
0.55	GO:0034341	response to interferon-gamma
0.37	GO:0006084	acetyl-CoA metabolic process

0.81	GO:0030429	kynureninase activity
0.66	GO:0030170	pyridoxal phosphate binding
0.50	GO:0042803	protein homodimerization activity

0.48	GO:0005737	cytoplasm
0.48	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.7.1.3

GO:0030429

sp|Q16720|AT2B3_HUMAN
Plasma membrane calcium-transporting ATPase 3
Search

ATP2B3

0.57	Plasma membrane calcium-transporting ATPase 3

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.58	GO:1990034	calcium ion export across plasma membrane
0.55	GO:0006874	cellular calcium ion homeostasis
0.40	GO:0007605	sensory perception of sound
0.39	GO:0007399	nervous system development
0.38	GO:0030154	cell differentiation
0.37	GO:0007423	sensory organ development
0.36	GO:0031214	biomineral tissue development
0.36	GO:0060322	head development

0.81	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0030165	PDZ domain binding
0.37	GO:0005516	calmodulin binding
0.35	GO:0030899	calcium-dependent ATPase activity
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0046872	metal ion binding

0.48	GO:0005794	Golgi apparatus
0.42	GO:0005887	integral component of plasma membrane
0.36	GO:1903561	extracellular vesicle
0.34	GO:0045121	membrane raft
0.34	GO:0016324	apical plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0005929	cilium
0.34	GO:0045202	synapse
0.34	GO:0030054	cell junction
0.33	GO:0005783	endoplasmic reticulum

0.81

EC:3.6.3.8

GO:0005388

sp|Q16739|CEGT_HUMAN
Ceramide glucosyltransferase
Search

UGCG

0.74	UDP-glucose ceramide glucosyltransferase

0.56	GO:1903955	positive regulation of protein targeting to mitochondrion
0.54	GO:0006687	glycosphingolipid metabolic process
0.50	GO:0046513	ceramide biosynthetic process
0.45	GO:0009247	glycolipid biosynthetic process
0.38	GO:0019377	glycolipid catabolic process
0.38	GO:0030149	sphingolipid catabolic process
0.37	GO:0048856	anatomical structure development
0.36	GO:0032501	multicellular organismal process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0003677	DNA binding

0.39	GO:0000139	Golgi membrane
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.65

GO:0016757

sp|Q16740|CLPP_HUMAN
ATP-dependent Clp protease proteolytic subunit, mitochondrial
Search

CLPP

0.42	ATP-dependent Clp protease proteolytic subunit

0.61	GO:0006508	proteolysis
0.47	GO:0044257	cellular protein catabolic process
0.37	GO:0051260	protein homooligomerization

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0042802	identical protein binding

0.55	GO:0009368	endopeptidase Clp complex
0.49	GO:0005759	mitochondrial matrix
0.30	GO:0044425	membrane part

0.69

GO:0004252

sp|Q16760|DGKD_HUMAN
Diacylglycerol kinase delta
Search

DGKD

0.49	Diacylglycerol kinase delta

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.52	GO:0051260	protein homooligomerization
0.49	GO:0010033	response to organic substance
0.39	GO:0046486	glycerolipid metabolic process
0.38	GO:0006638	neutral lipid metabolic process
0.37	GO:0006644	phospholipid metabolic process
0.35	GO:0007173	epidermal growth factor receptor signaling pathway
0.35	GO:0030168	platelet activation

0.80	GO:0004143	diacylglycerol kinase activity
0.75	GO:0003951	NAD+ kinase activity
0.69	GO:0042803	protein homodimerization activity
0.68	GO:0046982	protein heterodimerization activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0019992	diacylglycerol binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0004252	serine-type endopeptidase activity

0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.40	GO:0031410	cytoplasmic vesicle
0.37	GO:0012505	endomembrane system
0.34	GO:0005576	extracellular region
0.33	GO:0005634	nucleus

0.80	EC:2.7.1.107	GO:0004143
0.75	KEGG:R00104	GO:0003951

sp|Q16762|THTR_HUMAN
Thiosulfate sulfurtransferase
Search

TST

0.50	Thiosulfate sulfurtransferase

0.60	GO:0035928	rRNA import into mitochondrion
0.53	GO:0030855	epithelial cell differentiation
0.36	GO:0009440	cyanate catabolic process
0.34	GO:0016226	iron-sulfur cluster assembly
0.33	GO:0019221	cytokine-mediated signaling pathway
0.32	GO:0006508	proteolysis

0.78	GO:0004792	thiosulfate sulfurtransferase activity
0.54	GO:0008097	5S rRNA binding
0.33	GO:0004896	cytokine receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity

0.45	GO:0044429	mitochondrial part
0.45	GO:0019866	organelle inner membrane
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:2.8.1.1	GO:0004792
0.78	KEGG:R01931	GO:0004792

sp|Q16763|UBE2S_HUMAN
Ubiquitin-conjugating enzyme E2 S
Search

UBE2S

0.86	Ubiquitin-conjugating enzyme E2 S-A

0.64	GO:0010458	exit from mitosis
0.63	GO:0010994	free ubiquitin chain polymerization
0.61	GO:0070979	protein K11-linked ubiquitination
0.61	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.60	GO:0035519	protein K29-linked ubiquitination
0.60	GO:0044314	protein K27-linked ubiquitination
0.59	GO:0085020	protein K6-linked ubiquitination
0.59	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.57	GO:0070534	protein K63-linked ubiquitination
0.45	GO:0051301	cell division

0.57	GO:0061631	ubiquitin conjugating enzyme activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity

0.57	GO:0005680	anaphase-promoting complex
0.37	GO:0005737	cytoplasm
0.35	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.35

GO:0016874

sp|Q16769|QPCT_HUMAN
Glutaminyl-peptide cyclotransferase
Search

QPCT

0.88	Glutaminyl-peptide cyclotransferases

0.58	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
0.36	GO:0043312	neutrophil degranulation

0.84	GO:0016603	glutaminyl-peptide cyclotransferase activity
0.47	GO:0008270	zinc ion binding

0.39	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.3.2.5

GO:0016603

sp|Q16772|GSTA3_HUMAN
Glutathione S-transferase A3
Search

0.42	Glutathione S-transferase alpha I

0.46	GO:0006749	glutathione metabolic process
0.45	GO:0043651	linoleic acid metabolic process
0.44	GO:0060429	epithelium development
0.43	GO:0046222	aflatoxin metabolic process
0.42	GO:0098754	detoxification
0.41	GO:0030154	cell differentiation
0.41	GO:1901377	organic heteropentacyclic compound catabolic process
0.40	GO:1901685	glutathione derivative metabolic process
0.40	GO:0070887	cellular response to chemical stimulus
0.39	GO:0001823	mesonephros development

0.76	GO:0004364	glutathione transferase activity
0.42	GO:0004602	glutathione peroxidase activity
0.37	GO:0043295	glutathione binding
0.33	GO:0005515	protein binding
0.33	GO:0008144	drug binding

0.46	GO:0005829	cytosol
0.41	GO:0070062	extracellular exosome
0.37	GO:0005640	nuclear outer membrane

0.76

EC:2.5.1.18

GO:0004364

sp|Q16773|KAT1_HUMAN
Kynurenine--oxoglutarate transaminase 1
Search

0.95	Kynurenine--oxoglutarate transaminase 1

0.82	GO:0097052	L-kynurenine metabolic process
0.68	GO:0006575	cellular modified amino acid metabolic process
0.49	GO:0009058	biosynthetic process
0.41	GO:0042182	ketone catabolic process
0.39	GO:1901606	alpha-amino acid catabolic process
0.38	GO:1901361	organic cyclic compound catabolic process
0.38	GO:0019439	aromatic compound catabolic process
0.36	GO:0006558	L-phenylalanine metabolic process
0.36	GO:0042402	cellular biogenic amine catabolic process
0.36	GO:0006568	tryptophan metabolic process

0.86	GO:0047804	cysteine-S-conjugate beta-lyase activity
0.86	GO:0016212	kynurenine-oxoglutarate transaminase activity
0.78	GO:0070548	L-glutamine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.45	GO:0047312	L-phenylalanine:pyruvate aminotransferase activity
0.40	GO:0042803	protein homodimerization activity

0.40	GO:0005829	cytosol
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0044428	nuclear part
0.34	GO:0044429	mitochondrial part

0.86	EC:4.4.1.13	GO:0047804
0.45	KEGG:R00692	GO:0047312

sp|Q16774|KGUA_HUMAN
Guanylate kinase
Search

GUK1

0.45	Guanylate kinase

0.77	GO:0046710	GDP metabolic process
0.74	GO:0046037	GMP metabolic process
0.48	GO:0016310	phosphorylation
0.41	GO:0006185	dGDP biosynthetic process
0.41	GO:0046054	dGMP metabolic process
0.40	GO:0034436	glycoprotein transport
0.40	GO:0046060	dATP metabolic process
0.39	GO:0009180	purine ribonucleoside diphosphate biosynthetic process
0.38	GO:0019673	GDP-mannose metabolic process
0.37	GO:1901070	guanosine-containing compound biosynthetic process

0.78	GO:0004385	guanylate kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005829	cytosol
0.37	GO:0005922	connexin complex

0.78

EC:2.7.4.8

GO:0004385

sp|Q16775|GLO2_HUMAN
Hydroxyacylglutathione hydrolase, mitochondrial
Search

HAGH

0.47	Mitochondrial hydroxyacylglutathione hydrolase

0.79	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
0.52	GO:0006750	glutathione biosynthetic process
0.35	GO:0019853	L-ascorbic acid biosynthetic process
0.35	GO:0007283	spermatogenesis
0.34	GO:0006090	pyruvate metabolic process

0.79	GO:0004416	hydroxyacylglutathione hydrolase activity
0.37	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.42	GO:0005759	mitochondrial matrix
0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.79

EC:3.1.2.6

GO:0004416

sp|Q16777|H2A2C_HUMAN
Histone H2A type 2-C
Search

0.97	Histone H2A type 2-C

0.52	GO:0006342	chromatin silencing
0.36	GO:0006333	chromatin assembly or disassembly
0.36	GO:0034728	nucleosome organization
0.35	GO:0065004	protein-DNA complex assembly
0.35	GO:0006323	DNA packaging
0.34	GO:0032986	protein-DNA complex disassembly
0.34	GO:0070914	UV-damage excision repair

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.33	GO:0019899	enzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.39	GO:0070062	extracellular exosome

sp|Q16778|H2B2E_HUMAN
Histone H2B type 2-E
Search

sp|Q16787|LAMA3_HUMAN
Laminin subunit alpha-3
Search

0.54	Laminin subunit alpha 3

0.82	GO:0045995	regulation of embryonic development
0.78	GO:0030334	regulation of cell migration
0.75	GO:0030155	regulation of cell adhesion
0.72	GO:0007155	cell adhesion
0.56	GO:0035987	endodermal cell differentiation
0.46	GO:0031581	hemidesmosome assembly
0.34	GO:0060445	branching involved in salivary gland morphogenesis
0.34	GO:0008544	epidermis development
0.34	GO:0001658	branching involved in ureteric bud morphogenesis
0.34	GO:0001755	neural crest cell migration

0.71	GO:0005102	receptor binding
0.34	GO:0050839	cell adhesion molecule binding
0.33	GO:0032403	protein complex binding
0.32	GO:0005198	structural molecule activity

0.59	GO:0005610	laminin-5 complex
0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005608	laminin-3 complex
0.46	GO:0030056	hemidesmosome
0.44	GO:0005913	cell-cell adherens junction
0.43	GO:0070062	extracellular exosome
0.34	GO:0043259	laminin-10 complex
0.34	GO:0043083	synaptic cleft
0.31	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q16790|CAH9_HUMAN
Carbonic anhydrase 9
Search

CA9

0.95	Carbonic anhydrase XIV

0.71	GO:0006730	one-carbon metabolic process
0.61	GO:0002009	morphogenesis of an epithelium
0.55	GO:0046903	secretion
0.46	GO:0033574	response to testosterone
0.44	GO:0001666	response to hypoxia
0.41	GO:0042493	response to drug
0.38	GO:0015701	bicarbonate transport
0.38	GO:0036294	cellular response to decreased oxygen levels
0.38	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress
0.34	GO:0055064	chloride ion homeostasis

0.76	GO:0004089	carbonate dehydratase activity
0.62	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding

0.46	GO:0005886	plasma membrane
0.40	GO:0005902	microvillus
0.38	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0005730	nucleolus
0.33	GO:0031225	anchored component of membrane
0.30	GO:0016021	integral component of membrane

0.76

EC:4.2.1.1

GO:0004089

sp|Q16795|NDUA9_HUMAN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
Search

NDUFA9

0.37	NADH-ubiquinone oxidoreductase 39 kDa subunit

0.54	GO:1901006	ubiquinone-6 biosynthetic process
0.45	GO:0032981	mitochondrial respiratory chain complex I assembly
0.42	GO:0007623	circadian rhythm
0.41	GO:0055114	oxidation-reduction process
0.39	GO:0001666	response to hypoxia
0.38	GO:0006694	steroid biosynthetic process
0.37	GO:0009749	response to glucose
0.35	GO:0009651	response to salt stress
0.35	GO:0006814	sodium ion transport
0.34	GO:0006119	oxidative phosphorylation

0.54	GO:0050662	coenzyme binding
0.46	GO:0003954	NADH dehydrogenase activity
0.39	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.37	GO:0032403	protein complex binding
0.35	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.33	GO:0036094	small molecule binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0016831	carboxy-lyase activity
0.32	GO:0008144	drug binding
0.32	GO:0043168	anion binding

0.55	GO:0005747	mitochondrial respiratory chain complex I
0.42	GO:0005759	mitochondrial matrix
0.36	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.46

EC:1.6.99.3

GO:0003954

sp|Q16798|MAON_HUMAN
NADP-dependent malic enzyme, mitochondrial
Search

ME3

0.56	NADP-dependent malic enzyme, mitochondrial

0.54	GO:0006108	malate metabolic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006090	pyruvate metabolic process
0.39	GO:1902031	regulation of NADP metabolic process
0.38	GO:0051262	protein tetramerization
0.36	GO:0072592	oxygen metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.78	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity
0.67	GO:0051287	NAD binding
0.57	GO:0004473	malate dehydrogenase (decarboxylating) (NADP+) activity
0.54	GO:0046872	metal ion binding
0.38	GO:0008948	oxaloacetate decarboxylase activity

0.45	GO:0005739	mitochondrion
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.1.1.38 EC:1.1.1.39	GO:0004471
0.78	KEGG:R00214	GO:0004471

sp|Q16799|RTN1_HUMAN
Reticulon-1
Search

RTN1

0.78

Reticulon

0.38

GO:0030182

neuron differentiation

0.34	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005790	smooth endoplasmic reticulum
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q16816|PHKG1_HUMAN
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
Search

PHKG1

0.97	Phosphorylase kinase catalytic subunit gamma 1

0.76	GO:0005978	glycogen biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.49	GO:0018210	peptidyl-threonine modification
0.48	GO:0018209	peptidyl-serine modification
0.41	GO:0035556	intracellular signal transduction
0.39	GO:0001525	angiogenesis
0.35	GO:0005980	glycogen catabolic process

0.86	GO:0004689	phosphorylase kinase activity
0.79	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0050321	tau-protein kinase activity
0.36	GO:0019899	enzyme binding

0.85	GO:0005964	phosphorylase kinase complex
0.37	GO:0005829	cytosol
0.36	GO:0098723	skeletal muscle myofibril
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.7.11.19

GO:0004689

sp|Q16819|MEP1A_HUMAN
Meprin A subunit alpha
Search

MEP1A

0.92	Meprin A subunit alpha

0.61	GO:0006508	proteolysis
0.43	GO:0045766	positive regulation of angiogenesis
0.38	GO:0007586	digestion

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding

0.47	GO:0017090	meprin A complex
0.40	GO:0070062	extracellular exosome
0.36	GO:0005887	integral component of plasma membrane

0.70

GO:0004222

sp|Q16820|MEP1B_HUMAN
Meprin A subunit beta
Search

MEP1B

0.87	Meprin A subunit beta

0.64	GO:1901998	toxin transport
0.61	GO:0006508	proteolysis
0.42	GO:0006954	inflammatory response
0.38	GO:0007586	digestion

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.60	GO:0042802	identical protein binding

0.39	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

sp|Q16821|PPR3A_HUMAN
Protein phosphatase 1 regulatory subunit 3A
Search

PPP1R3A

0.95	Protein phosphatase 1 regulatory subunit 3A

0.40	GO:0005977	glycogen metabolic process
0.39	GO:0006470	protein dephosphorylation

0.39

GO:0004721

phosphoprotein phosphatase activity

0.30

GO:0031224

intrinsic component of membrane

0.39

GO:0004721

sp|Q16822|PCKGM_HUMAN
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
Search

PCK2

0.92	Acipenser baerii mitochondrial phosphoenolpyruvate carboxykinase mRNA

0.73	GO:0019319	hexose biosynthetic process
0.71	GO:0006006	glucose metabolic process
0.49	GO:0016310	phosphorylation
0.43	GO:0009749	response to glucose
0.41	GO:0071548	response to dexamethasone
0.41	GO:0006734	NADH metabolic process
0.40	GO:0048878	chemical homeostasis
0.40	GO:0071331	cellular response to hexose stimulus
0.40	GO:0071356	cellular response to tumor necrosis factor
0.39	GO:0032496	response to lipopolysaccharide

0.82	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.66	GO:0005525	GTP binding
0.51	GO:0016301	kinase activity
0.36	GO:0030145	manganese ion binding
0.35	GO:0019157	malate oxidase activity
0.35	GO:0047134	protein-disulfide reductase activity
0.35	GO:0019904	protein domain specific binding
0.35	GO:0003729	mRNA binding
0.35	GO:0051379	epinephrine binding
0.35	GO:0043177	organic acid binding

0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

0.82	EC:4.1.1.32	GO:0004613
0.35	KEGG:R00360	GO:0019157

sp|Q16825|PTN21_HUMAN
Tyrosine-protein phosphatase non-receptor type 21
Search

PTPN21

0.61	Tyrosine-protein phosphatase non-receptor type

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.43	GO:0001837	epithelial to mesenchymal transition
0.43	GO:0001756	somitogenesis
0.42	GO:0072359	circulatory system development
0.41	GO:0009887	animal organ morphogenesis
0.36	GO:0046825	regulation of protein export from nucleus
0.35	GO:0008285	negative regulation of cell proliferation
0.34	GO:0007010	cytoskeleton organization
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.74	GO:0004725	protein tyrosine phosphatase activity
0.36	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0003712	transcription cofactor activity

0.68	GO:0005856	cytoskeleton
0.45	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.74

GO:0004725

sp|Q16827|PTPRO_HUMAN
Receptor-type tyrosine-protein phosphatase O
Search

PTPRO

0.45	Receptor-type tyrosine-protein phosphatase O

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.64	GO:0036060	slit diaphragm assembly
0.62	GO:0003093	regulation of glomerular filtration
0.61	GO:0002548	monocyte chemotaxis
0.61	GO:0072112	glomerular visceral epithelial cell differentiation
0.60	GO:0030032	lamellipodium assembly
0.58	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.56	GO:0007411	axon guidance
0.49	GO:0051241	negative regulation of multicellular organismal process
0.40	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway

0.73	GO:0004725	protein tyrosine phosphatase activity
0.59	GO:0017147	Wnt-protein binding
0.53	GO:0042803	protein homodimerization activity
0.37	GO:0019198	transmembrane receptor protein phosphatase activity

0.59	GO:0016328	lateral plasma membrane
0.59	GO:0043197	dendritic spine
0.57	GO:0016324	apical plasma membrane
0.38	GO:0030426	growth cone
0.38	GO:0030027	lamellipodium
0.38	GO:0070062	extracellular exosome
0.37	GO:0030424	axon
0.34	GO:0005887	integral component of plasma membrane

0.73

GO:0004725

sp|Q16828|DUS6_HUMAN
Dual specificity protein phosphatase 6
Search

DUSP6

0.72	Dual specificity protein phosphatase

0.84	GO:0000188	inactivation of MAPK activity
0.71	GO:0006470	protein dephosphorylation
0.59	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.56	GO:0060420	regulation of heart growth
0.55	GO:0051409	response to nitrosative stress
0.53	GO:0010942	positive regulation of cell death
0.52	GO:0042663	regulation of endodermal cell fate specification
0.51	GO:0042981	regulation of apoptotic process
0.51	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.49	GO:0009953	dorsal/ventral pattern formation

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.68	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0016301	kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.42	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.32	GO:0005840	ribosome

0.85

GO:0017017

sp|Q16829|DUS7_HUMAN
Dual specificity protein phosphatase 7
Search

DUSP7

0.72	Dual specificity protein phosphatase

0.84	GO:0000188	inactivation of MAPK activity
0.71	GO:0006470	protein dephosphorylation
0.40	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.39	GO:0051409	response to nitrosative stress
0.38	GO:0043065	positive regulation of apoptotic process
0.38	GO:0060420	regulation of heart growth
0.37	GO:0042663	regulation of endodermal cell fate specification
0.36	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.36	GO:0009953	dorsal/ventral pattern formation
0.35	GO:0000187	activation of MAPK activity

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.66	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.47	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome

0.85

GO:0017017

sp|Q16831|UPP1_HUMAN
Uridine phosphorylase 1
Search

UPP1

0.59	Uridine phosphorylase

0.77	GO:0044206	UMP salvage
0.74	GO:0009166	nucleotide catabolic process
0.55	GO:0046108	uridine metabolic process
0.50	GO:0046135	pyrimidine nucleoside catabolic process
0.49	GO:0042454	ribonucleoside catabolic process
0.39	GO:0042149	cellular response to glucose starvation

0.82	GO:0004850	uridine phosphorylase activity
0.35	GO:0042802	identical protein binding

0.48	GO:0005737	cytoplasm
0.48	GO:0045098	type III intermediate filament
0.46	GO:0005654	nucleoplasm

0.82

EC:2.4.2.3

GO:0004850

sp|Q16832|DDR2_HUMAN
Discoidin domain-containing receptor 2
Search

DDR2

0.85	Discoidin domain receptor tyrosine kinase 2

0.85	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0090091	positive regulation of extracellular matrix disassembly
0.60	GO:0010763	positive regulation of fibroblast migration
0.60	GO:0035988	chondrocyte proliferation
0.59	GO:0003416	endochondral bone growth
0.58	GO:0048146	positive regulation of fibroblast proliferation
0.58	GO:0031214	biomineral tissue development
0.58	GO:0030199	collagen fibril organization
0.58	GO:0045669	positive regulation of osteoblast differentiation

0.85	GO:0038062	protein tyrosine kinase collagen receptor activity
0.56	GO:0005518	collagen binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0070569	uridylyltransferase activity

0.65	GO:0005887	integral component of plasma membrane
0.52	GO:0015629	actin cytoskeleton
0.41	GO:0016324	apical plasma membrane
0.39	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome

sp|Q16836|HCDH_HUMAN
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
Search

HADH

0.93	Mitochondrial hydroxyacyl-coenzyme a dehydrogenase

0.69	GO:0006631	fatty acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.39	GO:0046676	negative regulation of insulin secretion
0.39	GO:0014823	response to activity
0.38	GO:0032868	response to insulin
0.38	GO:0044242	cellular lipid catabolic process
0.37	GO:0030258	lipid modification
0.37	GO:0072329	monocarboxylic acid catabolic process
0.36	GO:0042493	response to drug
0.35	GO:0032958	inositol phosphate biosynthetic process

0.76	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.74	GO:0070403	NAD+ binding
0.34	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.34	GO:0008692	3-hydroxybutyryl-CoA epimerase activity
0.33	GO:0004300	enoyl-CoA hydratase activity
0.33	GO:0016301	kinase activity

0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.44	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:1.1.1.35

GO:0003857

sp|Q16842|SIA4B_HUMAN
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2
Search

ST3GAL2

0.94	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.53	GO:0030259	lipid glycosylation
0.51	GO:0009311	oligosaccharide metabolic process
0.50	GO:0009247	glycolipid biosynthetic process
0.48	GO:0016051	carbohydrate biosynthetic process
0.47	GO:0018196	peptidyl-asparagine modification
0.37	GO:0006468	protein phosphorylation
0.36	GO:0018146	keratan sulfate biosynthetic process
0.34	GO:0006054	N-acetylneuraminate metabolic process

0.84

GO:0008373

sialyltransferase activity

0.69	GO:0005794	Golgi apparatus
0.43	GO:0098588	bounding membrane of organelle
0.42	GO:0031984	organelle subcompartment
0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.99

GO:0008373

sp|Q16849|PTPRN_HUMAN
Receptor-type tyrosine-protein phosphatase-like N
Search

PTPRN

0.93	Protein tyrosine phosphatase receptor type N

0.77	GO:1904692	positive regulation of type B pancreatic cell proliferation
0.75	GO:1990502	dense core granule maturation
0.71	GO:0030073	insulin secretion
0.62	GO:0045944	positive regulation of transcription by RNA polymerase II
0.62	GO:0000302	response to reactive oxygen species
0.54	GO:0035335	peptidyl-tyrosine dephosphorylation
0.39	GO:0051591	response to cAMP
0.39	GO:0043627	response to estrogen
0.39	GO:0009749	response to glucose
0.38	GO:0032868	response to insulin

0.70	GO:0030507	spectrin binding
0.65	GO:0044389	ubiquitin-like protein ligase binding
0.60	GO:0008134	transcription factor binding
0.55	GO:0004725	protein tyrosine phosphatase activity
0.37	GO:0051020	GTPase binding

0.52	GO:0005634	nucleus
0.39	GO:0043679	axon terminus
0.38	GO:0043025	neuronal cell body
0.38	GO:0030141	secretory granule
0.37	GO:0005768	endosome
0.37	GO:0005794	Golgi apparatus
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.55

GO:0004725

sp|Q16850|CP51A_HUMAN
Lanosterol 14-alpha demethylase
Search

CYP51A1

0.88	Cytochrome P450 family 51 subfamily A member 1

0.58	GO:0070988	demethylation
0.57	GO:0001878	response to yeast
0.54	GO:0033488	cholesterol biosynthetic process via 24,25-dihydrolanosterol
0.53	GO:0055114	oxidation-reduction process
0.35	GO:0032259	methylation

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.59	GO:0032451	demethylase activity
0.35	GO:0008168	methyltransferase activity

0.59	GO:0005783	endoplasmic reticulum
0.39	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q16851|UGPA_HUMAN
UTP--glucose-1-phosphate uridylyltransferase
Search

UGP2

0.55	UTP--glucose-1-phosphate uridylyltransferase

0.76	GO:0006011	UDP-glucose metabolic process
0.44	GO:0005977	glycogen metabolic process
0.40	GO:0019255	glucose 1-phosphate metabolic process
0.35	GO:0006065	UDP-glucuronate biosynthetic process
0.34	GO:0009250	glucan biosynthetic process

0.77	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity
0.48	GO:0042802	identical protein binding
0.40	GO:0032557	pyrimidine ribonucleotide binding
0.38	GO:0005536	glucose binding
0.34	GO:0046872	metal ion binding

0.37	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77	EC:2.7.7.9	GO:0003983
0.77	KEGG:R00289	GO:0003983

sp|Q16853|AOC3_HUMAN
Membrane primary amine oxidase
Search

0.49	Retina-specific copper amine oxidase

0.70	GO:0009308	amine metabolic process
0.60	GO:0007601	visual perception
0.53	GO:1902283	negative regulation of primary amine oxidase activity
0.53	GO:0055114	oxidation-reduction process
0.46	GO:0007155	cell adhesion
0.45	GO:0046677	response to antibiotic
0.37	GO:0006954	inflammatory response
0.36	GO:0006584	catecholamine metabolic process
0.36	GO:0006805	xenobiotic metabolic process
0.36	GO:0035902	response to immobilization stress

0.83	GO:0008131	primary amine oxidase activity
0.72	GO:0048038	quinone binding
0.72	GO:0005507	copper ion binding
0.47	GO:0052593	tryptamine:oxygen oxidoreductase (deaminating) activity
0.47	GO:0052596	phenethylamine:oxygen oxidoreductase (deaminating) activity
0.47	GO:0052594	aminoacetone:oxygen oxidoreductase(deaminating) activity
0.47	GO:0052595	aliphatic-amine oxidase activity
0.45	GO:0046982	protein heterodimerization activity
0.44	GO:0005509	calcium ion binding
0.36	GO:0042803	protein homodimerization activity

0.49	GO:0005902	microvillus
0.47	GO:0005769	early endosome
0.47	GO:0009986	cell surface
0.44	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.40	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.36	GO:0008537	proteasome activator complex
0.30	GO:0016021	integral component of membrane

0.83	EC:1.4.3.21	GO:0008131
0.83	KEGG:R01853	GO:0008131

sp|Q16854|DGUOK_HUMAN
Deoxyguanosine kinase, mitochondrial
Search

DGUOK

0.65	Deoxyguanosine kinase, mitochondrial

0.62	GO:0046122	purine deoxyribonucleoside metabolic process
0.61	GO:0009165	nucleotide biosynthetic process
0.58	GO:0046070	dGTP metabolic process
0.56	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
0.53	GO:0016310	phosphorylation
0.45	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process
0.41	GO:0010977	negative regulation of neuron projection development
0.40	GO:0006220	pyrimidine nucleotide metabolic process
0.36	GO:0008617	guanosine metabolic process

0.75	GO:0019206	nucleoside kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042803	protein homodimerization activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0051213	dioxygenase activity
0.35	GO:0032546	deoxyribonucleoside binding
0.34	GO:0001884	pyrimidine nucleoside binding
0.34	GO:0003677	DNA binding

0.49	GO:0005829	cytosol
0.45	GO:0005739	mitochondrion
0.40	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|Q16864|VATF_HUMAN
V-type proton ATPase subunit F
Search

ATP6V1F

0.72	V-type proton ATPase subunit F

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.46	GO:1901207	regulation of heart looping
0.45	GO:0060036	notochord cell vacuolation
0.44	GO:0070121	Kupffer's vesicle development
0.44	GO:1902017	regulation of cilium assembly
0.43	GO:0060041	retina development in camera-type eye
0.41	GO:0042127	regulation of cell proliferation
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0008286	insulin receptor signaling pathway

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.34	GO:0004749	ribose phosphate diphosphokinase activity
0.34	GO:0042624	ATPase activity, uncoupled
0.33	GO:0000287	magnesium ion binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.46	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.43	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.34	EC:2.7.6.1	GO:0004749
0.34	KEGG:R01049	GO:0004749

sp|Q16873|LTC4S_HUMAN
Leukotriene C4 synthase
Search

LTC4S

0.96	Microsomal glutathione S-transferase 2

0.84	GO:0006691	leukotriene metabolic process
0.70	GO:0043085	positive regulation of catalytic activity
0.54	GO:0046456	icosanoid biosynthetic process
0.46	GO:0098869	cellular oxidant detoxification
0.38	GO:0071299	cellular response to vitamin A
0.38	GO:2001300	lipoxin metabolic process
0.37	GO:0019372	lipoxygenase pathway
0.36	GO:0006636	unsaturated fatty acid biosynthetic process
0.36	GO:0048678	response to axon injury
0.36	GO:0071222	cellular response to lipopolysaccharide

0.71	GO:0008047	enzyme activator activity
0.68	GO:0004464	leukotriene-C4 synthase activity
0.54	GO:0042802	identical protein binding
0.54	GO:0008289	lipid binding
0.50	GO:0004364	glutathione transferase activity
0.50	GO:0004602	glutathione peroxidase activity
0.36	GO:0043295	glutathione binding
0.35	GO:0046982	protein heterodimerization activity

0.57	GO:0005635	nuclear envelope
0.54	GO:0005783	endoplasmic reticulum
0.42	GO:0031968	organelle outer membrane
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.68	EC:4.4.1.20	GO:0004464
0.68	KEGG:R03059	GO:0004464

sp|Q16875|F263_HUMAN
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
Search

PFKFB3

0.96	Inducible 6-phosphofructo-2-kinase

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.39	GO:0016311	dephosphorylation
0.37	GO:0007420	brain development
0.37	GO:0006110	regulation of glycolytic process
0.35	GO:0051197	positive regulation of coenzyme metabolic process
0.35	GO:1903580	positive regulation of ATP metabolic process
0.35	GO:0045913	positive regulation of carbohydrate metabolic process
0.34	GO:0031331	positive regulation of cellular catabolic process

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity

0.49	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

sp|Q16877|F264_HUMAN
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
Search

PFKFB4

0.96	6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.40	GO:0016311	dephosphorylation
0.35	GO:0045821	positive regulation of glycolytic process

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity

0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

sp|Q16878|CDO1_HUMAN
Cysteine dioxygenase type 1
Search

CDO1

0.58	Cysteine dioxygenase type I

0.51	GO:0055114	oxidation-reduction process
0.44	GO:0046305	alkanesulfonate biosynthetic process
0.42	GO:0019530	taurine metabolic process
0.40	GO:0019448	L-cysteine catabolic process
0.39	GO:0033762	response to glucagon
0.39	GO:0007595	lactation
0.39	GO:0051591	response to cAMP
0.39	GO:0051384	response to glucocorticoid
0.39	GO:0045471	response to ethanol
0.38	GO:0043200	response to amino acid

0.72	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.61	GO:0005506	iron ion binding

0.47	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

0.72

EC:1.13.11

GO:0016702

sp|Q16880|CGT_HUMAN
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
Search

UGT8

0.53	UDP-galactose ceramide galactosyltransferase

0.58	GO:0002175	protein localization to paranode region of axon
0.57	GO:0030913	paranodal junction assembly
0.51	GO:0048812	neuron projection morphogenesis
0.48	GO:0007010	cytoskeleton organization
0.39	GO:0006682	galactosylceramide biosynthetic process
0.35	GO:0007422	peripheral nervous system development
0.35	GO:0007417	central nervous system development

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.55	GO:0008194	UDP-glycosyltransferase activity

0.38	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0016758

sp|Q16881|TRXR1_HUMAN
Thioredoxin reductase 1, cytoplasmic
Search

TXNRD1

0.75	LOW QUALITY PROTEIN: thioredoxin reductase 1, cytoplasmic

0.68	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.59	GO:0022900	electron transport chain
0.53	GO:0001707	mesoderm formation
0.51	GO:0008283	cell proliferation
0.44	GO:0000305	response to oxygen radical
0.36	GO:0070276	halogen metabolic process
0.36	GO:0015949	nucleobase-containing small molecule interconversion
0.36	GO:0070995	NADPH oxidation
0.36	GO:0010269	response to selenium ion

0.78	GO:0004791	thioredoxin-disulfide reductase activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.60	GO:0009055	electron transfer activity
0.54	GO:0015035	protein disulfide oxidoreductase activity
0.38	GO:0098626	methylseleninic acid reductase activity
0.38	GO:0098625	methylselenol reductase activity
0.37	GO:0098623	selenite reductase activity
0.36	GO:0033797	selenate reductase activity
0.35	GO:0016174	NAD(P)H oxidase activity
0.35	GO:0045340	mercury ion binding

0.55	GO:0001650	fibrillar center
0.51	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.45	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.35	GO:0043025	neuronal cell body
0.34	GO:0005783	endoplasmic reticulum
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.8.1.9	GO:0004791
0.78	KEGG:R02016	GO:0004791

sp|Q16890|TPD53_HUMAN
Tumor protein D53
Search

TPD52L1

0.97	Tumor protein D52 like 1

0.76	GO:0000086	G2/M transition of mitotic cell cycle
0.71	GO:0046330	positive regulation of JNK cascade
0.70	GO:2001235	positive regulation of apoptotic signaling pathway
0.68	GO:0043406	positive regulation of MAP kinase activity
0.55	GO:0030183	B cell differentiation

0.72	GO:0042803	protein homodimerization activity
0.68	GO:0046982	protein heterodimerization activity
0.48	GO:0005509	calcium ion binding

0.76	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0005769	early endosome
0.48	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|Q16891|MIC60_HUMAN
MICOS complex subunit MIC60
Search

IMMT

0.71	MICOS complex subunit MIC60

0.57	GO:0051560	mitochondrial calcium ion homeostasis
0.56	GO:0042407	cristae formation
0.34	GO:0009409	response to cold

0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.54	GO:0043209	myelin sheath
0.52	GO:0031301	integral component of organelle membrane
0.51	GO:0098798	mitochondrial protein complex
0.45	GO:0098796	membrane protein complex

sp|Q17R31|TATD3_HUMAN
Putative deoxyribonuclease TATDN3
Search

TATDN3

0.95	TatD DNase domain containing 3

0.34

GO:0006259

DNA metabolic process

0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.34	GO:0140097	catalytic activity, acting on DNA

0.61

GO:0016788

sp|Q17R55|F187B_HUMAN
Protein FAM187B
Search

sp|Q17R60|IMPG1_HUMAN
Interphotoreceptor matrix proteoglycan 1
Search

IMPG1

0.92	Interphotoreceptor matrix proteoglycan 1

0.56

GO:0007601

visual perception

0.57	GO:0005201	extracellular matrix structural constituent
0.37	GO:0051015	actin filament binding
0.37	GO:0003774	motor activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0005576	extracellular region
0.37	GO:0016459	myosin complex
0.30	GO:0044425	membrane part

sp|Q17R89|RHG44_HUMAN
Rho GTPase-activating protein 44
Search

ARHGAP44

0.94	Rho GTPase-activating protein 44

0.75	GO:0043547	positive regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.56	GO:0098886	modification of dendritic spine
0.56	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane
0.55	GO:0035021	negative regulation of Rac protein signal transduction
0.53	GO:0061001	regulation of dendritic spine morphogenesis
0.49	GO:0032956	regulation of actin cytoskeleton organization
0.37	GO:0006887	exocytosis
0.35	GO:0099003	vesicle-mediated transport in synapse

0.76	GO:0005096	GTPase activator activity
0.53	GO:0048365	Rac GTPase binding
0.50	GO:0005543	phospholipid binding

0.54	GO:0031256	leading edge membrane
0.52	GO:0043197	dendritic spine
0.49	GO:0005737	cytoplasm
0.38	GO:0030054	cell junction
0.37	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.35	GO:0014069	postsynaptic density
0.35	GO:0048786	presynaptic active zone
0.34	GO:0005887	integral component of plasma membrane

sp|Q17R98|ZN827_HUMAN
Zinc finger protein 827
Search

ZNF827

0.82	Zinc finger protein 827

0.32	GO:0097659	nucleic acid-templated transcription
0.32	GO:0006355	regulation of transcription, DNA-templated
0.32	GO:0010467	gene expression
0.32	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.32	GO:0046872	metal ion binding
0.31	GO:0005515	protein binding

0.32

GO:0005634

nucleus

sp|Q17RA5|CMAS1_HUMAN
Putative uncharacterized protein C21orf62-AS1
Search

sp|Q17RB0|F127C_HUMAN
Protein FAM127C
Search

0.97	Mammalian retrotransposon derived protein 8B

0.63

GO:0005515

protein binding

sp|Q17RB8|LONF1_HUMAN
LON peptidase N-terminal domain and RING finger protein 1
Search

LONRF1

0.90	LON peptidase N-terminal domain and RING finger protein 1

0.64	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.62	GO:0000209	protein polyubiquitination
0.35	GO:0006879	cellular iron ion homeostasis

0.65	GO:0031624	ubiquitin conjugating enzyme binding
0.60	GO:0004842	ubiquitin-protein transferase activity
0.58	GO:0061659	ubiquitin-like protein ligase activity
0.51	GO:0046872	metal ion binding

0.39	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.60

GO:0004842

sp|Q17RC7|EX3L4_HUMAN
Exocyst complex component 3-like protein 4
Search

EXOC3L4

0.97	Exocyst complex component 3 like 4

0.77	GO:0006887	exocytosis
0.61	GO:0051601	exocyst localization
0.34	GO:0006757	ATP generation from ADP
0.34	GO:0006090	pyruvate metabolic process
0.34	GO:0016052	carbohydrate catabolic process
0.34	GO:0046496	nicotinamide nucleotide metabolic process

0.56	GO:0000149	SNARE binding
0.34	GO:0004634	phosphopyruvate hydratase activity
0.33	GO:0000287	magnesium ion binding

0.79	GO:0000145	exocyst
0.34	GO:0000015	phosphopyruvate hydratase complex

0.34

EC:4.2.1.11

GO:0004634

sp|Q17RD7|SYT16_HUMAN
Synaptotagmin-16
Search

SYT16

0.97	Synaptotagmin-16 isoform A

0.75	GO:0006887	exocytosis
0.51	GO:0017158	regulation of calcium ion-dependent exocytosis
0.50	GO:0048489	synaptic vesicle transport
0.50	GO:0099504	synaptic vesicle cycle
0.50	GO:0006906	vesicle fusion
0.49	GO:0099643	signal release from synapse
0.49	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.47	GO:0006836	neurotransmitter transport
0.46	GO:0001505	regulation of neurotransmitter levels

0.54	GO:0005543	phospholipid binding
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.50	GO:0019905	syntaxin binding
0.49	GO:0030276	clathrin binding
0.45	GO:0005509	calcium ion binding

0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q17RF5|CD026_HUMAN
Uncharacterized protein C4orf26
Search

ODAPH

0.86	Odontogenesis associated phosphoprotein

0.87

GO:0070175

positive regulation of enamel mineralization

0.51

GO:0005515

protein binding

0.54

GO:0005576

extracellular region

sp|Q17RG1|KCD19_HUMAN
BTB/POZ domain-containing protein KCTD19
Search

KCTD19

0.96	Potassium channel tetramerization domain containing 19

0.78	GO:0051260	protein homooligomerization
0.37	GO:0007406	negative regulation of neuroblast proliferation
0.37	GO:0045879	negative regulation of smoothened signaling pathway
0.37	GO:0045666	positive regulation of neuron differentiation

0.35

GO:0042802

identical protein binding

0.33

GO:0005737

cytoplasm

sp|Q17RH7|TPRXL_HUMAN
Putative protein TPRXL
Search

0.11	Putative protein TPRXL

0.43	GO:0006508	proteolysis
0.42	GO:0006281	DNA repair
0.42	GO:0006396	RNA processing
0.41	GO:0016072	rRNA metabolic process
0.41	GO:0045332	phospholipid translocation
0.41	GO:0006266	DNA ligation
0.41	GO:0042254	ribosome biogenesis
0.40	GO:0070588	calcium ion transmembrane transport
0.39	GO:0006629	lipid metabolic process
0.39	GO:0071897	DNA biosynthetic process

0.43	GO:0016787	hydrolase activity
0.43	GO:0000166	nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.42	GO:0004484	mRNA guanylyltransferase activity
0.42	GO:0030983	mismatched DNA binding
0.42	GO:0008144	drug binding
0.41	GO:0008270	zinc ion binding

0.44	GO:0032300	mismatch repair complex
0.35	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.43

GO:0016787

sp|Q17RM4|CC142_HUMAN
Coiled-coil domain-containing protein 142
Search

CCDC142

0.97	Coiled-coil domain-containing protein 142

0.30

GO:0044425

membrane part

sp|Q17RN3|FA98C_HUMAN
Protein FAM98C
Search

sp|Q17RP2|TIGD6_HUMAN
Tigger transposable element-derived protein 6
Search

TIGD6

0.77	LOW QUALITY PROTEIN: tigger transposable element-derived protein 6

0.54

GO:0003677

DNA binding

0.55

GO:0005634

nucleus

sp|Q17RQ9|NKPD1_HUMAN
NTPase KAP family P-loop domain-containing protein 1
Search

NKPD1

0.97	NTPase KAP family P-loop domain-containing protein 1

0.34

GO:0003676

nucleic acid binding

0.30

GO:0044425

membrane part

sp|Q17RR3|LIPR3_HUMAN
Pancreatic lipase-related protein 3
Search

0.58	Pancreatic triacylglycerol lipase

0.66	GO:0016042	lipid catabolic process
0.49	GO:0007586	digestion
0.45	GO:0006968	cellular defense response
0.44	GO:0061365	positive regulation of triglyceride lipase activity
0.43	GO:0030301	cholesterol transport
0.40	GO:0003008	system process
0.39	GO:0019374	galactolipid metabolic process
0.36	GO:0046434	organophosphate catabolic process
0.36	GO:1901136	carbohydrate derivative catabolic process
0.36	GO:0006644	phospholipid metabolic process

0.78	GO:0004806	triglyceride lipase activity
0.40	GO:0102549	1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity
0.40	GO:0047714	galactolipase activity
0.38	GO:0047372	acylglycerol lipase activity
0.38	GO:0005509	calcium ion binding
0.37	GO:0004620	phospholipase activity
0.33	GO:0005515	protein binding
0.33	GO:0043565	sequence-specific DNA binding

0.66	GO:0005576	extracellular region
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.78

EC:3.1.1.3

GO:0004806

sp|Q17RS7|GEN_HUMAN
Flap endonuclease GEN homolog 1
Search

GEN1

0.96	Flap endonuclease GEN like protein 1

0.66	GO:0071140	resolution of mitotic recombination intermediates
0.64	GO:0006281	DNA repair
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.63	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.60	GO:0010824	regulation of centrosome duplication

0.63	GO:0004518	nuclease activity
0.52	GO:0003677	DNA binding
0.48	GO:0140097	catalytic activity, acting on DNA
0.34	GO:0046872	metal ion binding

0.56	GO:0005813	centrosome
0.39	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0004518

sp|Q17RW2|COOA1_HUMAN
Collagen alpha-1(XXIV) chain
Search

COL24A1

0.70	Collagen type XXVII alpha 1 chain

0.53	GO:0048513	animal organ development
0.52	GO:0030154	cell differentiation
0.51	GO:0003416	endochondral bone growth
0.49	GO:0002520	immune system development
0.48	GO:0061448	connective tissue development
0.48	GO:0001501	skeletal system development
0.48	GO:0030198	extracellular matrix organization
0.45	GO:0009653	anatomical structure morphogenesis
0.34	GO:0001503	ossification
0.34	GO:0009790	embryo development

0.76	GO:0005201	extracellular matrix structural constituent
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.67	GO:0005581	collagen trimer
0.51	GO:0098643	banded collagen fibril
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q17RY0|CPEB4_HUMAN
Cytoplasmic polyadenylation element-binding protein 4
Search

CPEB4

0.94	Cytoplasmic polyadenylation element binding protein 4

0.71	GO:0006417	regulation of translation
0.57	GO:0002931	response to ischemia
0.55	GO:0071230	cellular response to amino acid stimulus
0.45	GO:0034249	negative regulation of cellular amide metabolic process
0.43	GO:0032269	negative regulation of cellular protein metabolic process
0.43	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.42	GO:0010629	negative regulation of gene expression
0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0042149	cellular response to glucose starvation
0.39	GO:0036294	cellular response to decreased oxygen levels

0.82	GO:0003730	mRNA 3'-UTR binding
0.82	GO:0045182	translation regulator activity
0.44	GO:0043022	ribosome binding
0.42	GO:0008135	translation factor activity, RNA binding
0.35	GO:0032051	clathrin light chain binding
0.33	GO:0046872	metal ion binding

0.55	GO:0014069	postsynaptic density
0.53	GO:0043005	neuron projection
0.53	GO:0036477	somatodendritic compartment
0.51	GO:0120038	plasma membrane bounded cell projection part
0.49	GO:1990124	messenger ribonucleoprotein complex
0.49	GO:0005783	endoplasmic reticulum
0.46	GO:0005634	nucleus
0.37	GO:0030427	site of polarized growth
0.37	GO:0045211	postsynaptic membrane
0.37	GO:0048471	perinuclear region of cytoplasm

sp|Q17RY6|LY6K_HUMAN
Lymphocyte antigen 6K
Search

LY6K

0.93	Lymphocyte antigen 6 family member K

0.58

GO:0006501

C-terminal protein lipidation

0.56	GO:0001669	acrosomal vesicle
0.54	GO:0098857	membrane microdomain
0.54	GO:0031225	anchored component of membrane
0.48	GO:0005576	extracellular region
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q18PE1|DOK7_HUMAN
Protein Dok-7
Search

DOK7

0.97	Docking protein 7

0.85	GO:0061098	positive regulation of protein tyrosine kinase activity
0.44	GO:0007528	neuromuscular junction development
0.42	GO:0048741	skeletal muscle fiber development
0.38	GO:0043113	receptor clustering
0.33	GO:0006508	proteolysis
0.32	GO:0016310	phosphorylation

0.78	GO:0019901	protein kinase binding
0.38	GO:0008289	lipid binding
0.33	GO:0043168	anion binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0016301	kinase activity

0.49	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.39	GO:0045202	synapse
0.38	GO:0030054	cell junction
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004252

sp|Q19AV6|ZSWM7_HUMAN
Zinc finger SWIM domain-containing protein 7
Search

ZSWIM7

0.96	Zinc finger SWIM domain-containing protein 7

0.59	GO:0050821	protein stabilization
0.58	GO:0000724	double-strand break repair via homologous recombination

0.63	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding

0.65	GO:0097196	Shu complex
0.37	GO:0005634	nucleus

sp|Q19T08|ECSCR_HUMAN
Endothelial cell-specific chemotaxis regulator
Search

ECSCR

0.97	Endothelial cell surface-expressed chemotaxis and apoptosis regulator

0.55	GO:0016525	negative regulation of angiogenesis
0.52	GO:2000353	positive regulation of endothelial cell apoptotic process
0.51	GO:0001525	angiogenesis
0.50	GO:0006915	apoptotic process
0.49	GO:1901800	positive regulation of proteasomal protein catabolic process
0.47	GO:0030154	cell differentiation
0.47	GO:0006935	chemotaxis

0.39

GO:0005515

protein binding

0.48	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.43	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|Q1A5X6|IQCJ_HUMAN
IQ domain-containing protein J
Search

IQCJ

0.97	IQ domain-containing protein J

0.70

GO:0031492

nucleosomal DNA binding

0.60	GO:0000785	chromatin
0.52	GO:0005634	nucleus

sp|Q1A5X7|WHAL1_HUMAN
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1
Search

WHAMM

0.67	WAS protein homolog associated with actin, golgi membranes and microtubules

0.69	GO:0048041	focal adhesion assembly
0.68	GO:0030032	lamellipodium assembly
0.68	GO:0097320	plasma membrane tubulation
0.67	GO:0051127	positive regulation of actin nucleation
0.64	GO:0006888	ER to Golgi vesicle-mediated transport
0.62	GO:0007015	actin filament organization
0.61	GO:0031532	actin cytoskeleton reorganization
0.57	GO:0007050	cell cycle arrest

0.73	GO:0003779	actin binding
0.71	GO:0071933	Arp2/3 complex binding
0.70	GO:0017049	GTP-Rho binding
0.59	GO:0008017	microtubule binding

0.70	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.59	GO:0000139	Golgi membrane
0.55	GO:0005829	cytosol
0.40	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0005874	microtubule

sp|Q1AE95|T183B_HUMAN
Transmembrane protein 183B
Search

TMEM183A

0.93	Transmembrane domain-containing protein (Fragment)

0.33

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q1ED39|KNOP1_HUMAN
Lysine-rich nucleolar protein 1
Search

KNOP1

0.97	Lysine-rich nucleolar protein 1

0.53

GO:0003723

RNA binding

0.67

GO:0005730

nucleolus

sp|Q1EHB4|SC5AC_HUMAN
Sodium-coupled monocarboxylate transporter 2
Search

SLC5A12

0.94	Solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12

0.66

GO:0035873

lactate transmembrane transport

0.66

GO:0015129

lactate transmembrane transporter activity

0.39	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q1HG43|DOXA1_HUMAN
Dual oxidase maturation factor 1
Search

DUOXA1

0.95	Dual oxidase maturation factor 1 alpha

0.66	GO:2000609	regulation of thyroid hormone generation
0.64	GO:0015031	protein transport
0.60	GO:0050727	regulation of inflammatory response
0.57	GO:0042743	hydrogen peroxide metabolic process
0.55	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.54	GO:0045666	positive regulation of neuron differentiation

0.33

GO:0005515

protein binding

0.70	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q1HG44|DOXA2_HUMAN
Dual oxidase maturation factor 2
Search

DUOXA2

0.94	Dual oxidase maturation factor 1 alpha

0.70	GO:2000609	regulation of thyroid hormone generation
0.65	GO:0015031	protein transport
0.63	GO:0050727	regulation of inflammatory response
0.60	GO:0042743	hydrogen peroxide metabolic process
0.52	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.50	GO:0045666	positive regulation of neuron differentiation

0.33

GO:0005515

protein binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q1KMD3|HNRL2_HUMAN
Heterogeneous nuclear ribonucleoprotein U-like protein 2
Search

0.84	Heterogeneous nuclear ribonucleoprotein U

0.45	GO:1990280	RNA localization to chromatin
0.44	GO:0070934	CRD-mediated mRNA stabilization
0.44	GO:1902889	protein localization to spindle microtubule
0.44	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore
0.44	GO:0009615	response to virus
0.44	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.44	GO:2000737	negative regulation of stem cell differentiation
0.43	GO:0032211	negative regulation of telomere maintenance via telomerase
0.43	GO:1901673	regulation of mitotic spindle assembly
0.43	GO:0051457	maintenance of protein location in nucleus

0.45	GO:0017130	poly(C) RNA binding
0.45	GO:0001097	TFIIH-class transcription factor binding
0.44	GO:0034046	poly(G) binding
0.44	GO:0099122	RNA polymerase II C-terminal domain binding
0.44	GO:0070034	telomerase RNA binding
0.43	GO:1990841	promoter-specific chromatin binding
0.43	GO:0008143	poly(A) binding
0.43	GO:0036002	pre-mRNA binding
0.42	GO:0031490	chromatin DNA binding
0.42	GO:0003730	mRNA 3'-UTR binding

0.59	GO:0019013	viral nucleocapsid
0.54	GO:0005634	nucleus
0.53	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0098577	inactive sex chromosome
0.44	GO:0070937	CRD-mediated mRNA stability complex
0.44	GO:1990498	mitotic spindle microtubule
0.43	GO:1990023	mitotic spindle midzone
0.42	GO:0030496	midbody
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0000776	kinetochore

sp|Q1L5Z9|LONF2_HUMAN
LON peptidase N-terminal domain and RING finger protein 2
Search

LONRF2

0.91	LON peptidase N-terminal domain and RING finger protein 2

0.64	GO:0016567	protein ubiquitination
0.63	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.37	GO:0006879	cellular iron ion homeostasis

0.65	GO:0031624	ubiquitin conjugating enzyme binding
0.65	GO:0004842	ubiquitin-protein transferase activity
0.58	GO:0061659	ubiquitin-like protein ligase activity
0.48	GO:0046872	metal ion binding

0.39	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.65

GO:0004842

sp|Q1L6U9|MSMP_HUMAN
Prostate-associated microseminoprotein
Search

MSMP

0.93	Microseminoprotein, prostate associated

0.67	GO:0005615	extracellular space
0.46	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q1MSJ5|CSPP1_HUMAN
Centrosome and spindle pole-associated protein 1
Search

CSPP1

0.96	Centrosome and spindle pole-associated protein 1

0.84

GO:0032467

positive regulation of cytokinesis

0.36

GO:0005515

protein binding

0.79	GO:0000922	spindle pole
0.77	GO:0005813	centrosome
0.73	GO:0005874	microtubule
0.34	GO:0005737	cytoplasm

sp|Q1MX18|INSC_HUMAN
Protein inscuteable homolog
Search

INSC

0.97	INSC, spindle orientation adaptor protein (Fragment)

0.79

GO:0031647

regulation of protein stability

0.80	GO:0030674	protein binding, bridging
0.77	GO:0019904	protein domain specific binding

0.76	GO:0005938	cell cortex
0.60	GO:0043234	protein complex
0.56	GO:0005886	plasma membrane

sp|Q1RMZ1|BMT2_HUMAN
Probable methyltransferase BMT2 homolog
Search

BMT2

0.87	Probable methyltransferase BMT2 homolog

0.71	GO:0031167	rRNA methylation
0.65	GO:1904262	negative regulation of TORC1 signaling
0.63	GO:0034198	cellular response to amino acid starvation
0.34	GO:0050790	regulation of catalytic activity

0.76	GO:0016433	rRNA (adenine) methyltransferase activity
0.58	GO:1904047	S-adenosyl-L-methionine binding
0.35	GO:0030695	GTPase regulator activity
0.31	GO:0003676	nucleic acid binding

0.67	GO:0140007	KICSTOR complex
0.65	GO:1990130	GATOR1 complex
0.46	GO:0005730	nucleolus

0.76

GO:0016433

sp|Q1RN00|YC018_HUMAN
Putative uncharacterized protein LOC151760
Search

sp|Q1T7F1|CCB42_HUMAN
Putative chemokine-related protein B42
Search

sp|Q1W209|ESRG_HUMAN
Embryonic stem cell-related gene protein
Search

0.93	Embryonic stem cell related protein (Fragment)

0.61

GO:0005634

nucleus

sp|Q1W4C9|ISK13_HUMAN
Serine protease inhibitor Kazal-type 13
Search

SPINK13

0.97	Serine protease inhibitor Kazal-type 13

0.78	GO:1900004	negative regulation of serine-type endopeptidase activity
0.77	GO:0060046	regulation of acrosome reaction
0.68	GO:0060467	negative regulation of fertilization
0.43	GO:0006508	proteolysis

0.68	GO:0004867	serine-type endopeptidase inhibitor activity
0.44	GO:0008233	peptidase activity

0.72	GO:0001669	acrosomal vesicle
0.64	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.44

GO:0008233

sp|Q1W6H9|F110C_HUMAN
Protein FAM110C
Search

0.72	GO:0051897	positive regulation of protein kinase B signaling
0.69	GO:0030335	positive regulation of cell migration
0.68	GO:0060491	regulation of cell projection assembly

0.74

GO:0043014

alpha-tubulin binding

0.65	GO:0005938	cell cortex
0.55	GO:0005829	cytosol
0.50	GO:0005815	microtubule organizing center
0.50	GO:0005739	mitochondrion
0.47	GO:0000922	spindle pole
0.45	GO:0005874	microtubule
0.41	GO:0005634	nucleus

sp|Q1X8D7|LRC36_HUMAN
Leucine-rich repeat-containing protein 36
Search

LRRC36

0.97	Leucine-rich repeat-containing protein 36

sp|Q1XH10|SKDA1_HUMAN
SKI/DACH domain-containing protein 1
Search

SKIDA1

0.96	SKI/DACH domain-containing protein 1

sp|Q1ZYL8|IZUM4_HUMAN
Izumo sperm-egg fusion protein 4
Search

IZUMO4

0.97	Izumo sperm-egg fusion protein 4

0.44	GO:0034729	histone H3-K79 methylation
0.41	GO:0051726	regulation of cell cycle

0.44

GO:0031151

histone methyltransferase activity (H3-K79 specific)

0.59	GO:0005634	nucleus
0.52	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q1ZZU3|SWI5_HUMAN
DNA repair protein SWI5 homolog
Search

SWI5

0.94	DNA repair protein SWI5 homolog

0.81	GO:0071479	cellular response to ionizing radiation
0.75	GO:0000724	double-strand break repair via homologous recombination
0.73	GO:0090735	DNA repair complex assembly
0.65	GO:0065004	protein-DNA complex assembly
0.40	GO:0072583	clathrin-dependent endocytosis
0.34	GO:0016310	phosphorylation
0.34	GO:0045454	cell redox homeostasis

0.41	GO:0005515	protein binding
0.39	GO:0003924	GTPase activity
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003677	DNA binding
0.34	GO:0016301	kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding

0.86

GO:0032798

Swi5-Sfr1 complex

sp|Q24JP5|T132A_HUMAN
Transmembrane protein 132A
Search

TMEM132A

0.92	Transmembrane protein 132A

0.41	GO:0043687	post-translational protein modification
0.40	GO:0007420	brain development
0.40	GO:0043069	negative regulation of programmed cell death
0.34	GO:0010923	negative regulation of phosphatase activity

0.37

GO:0005515

protein binding

0.47	GO:0005794	Golgi apparatus
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0070062	extracellular exosome
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0098588	bounding membrane of organelle
0.43	GO:0031984	organelle subcompartment
0.38	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

sp|Q24JQ0|TM241_HUMAN
Transmembrane protein 241
Search

TMEM241

0.97	Transmembrane protein 241

0.52

GO:1990570

GDP-mannose transmembrane transport

0.50

GO:0005338

nucleotide-sugar transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|Q27J81|INF2_HUMAN
Inverted formin-2
Search

INF2

0.83	LOW QUALITY PROTEIN: inverted formin-2

0.73	GO:0030036	actin cytoskeleton organization
0.59	GO:0090140	regulation of mitochondrial fission
0.33	GO:0032535	regulation of cellular component size

0.73	GO:0003779	actin binding
0.71	GO:0017048	Rho GTPase binding

0.54

GO:0048471

perinuclear region of cytoplasm

sp|Q29980|MICB_HUMAN
MHC class I polypeptide-related sequence B
Search

0.55	MICA protein (Fragment)

0.30

GO:0044425

membrane part

sp|Q29983|MICA_HUMAN
MHC class I polypeptide-related sequence A
Search

MICA

0.66	MICA protein (Fragment)

0.30

GO:0044425

membrane part

sp|Q29RF7|PDS5A_HUMAN
Sister chromatid cohesion protein PDS5 homolog A
Search

PDS5A

0.93	Sister chromatid cohesion protein PDS5 like protein A

0.80	GO:0007064	mitotic sister chromatid cohesion
0.75	GO:0008156	negative regulation of DNA replication
0.51	GO:0006281	DNA repair
0.45	GO:0051301	cell division
0.45	GO:0008285	negative regulation of cell proliferation
0.34	GO:0055114	oxidation-reduction process

0.38	GO:0003677	DNA binding
0.37	GO:0005515	protein binding
0.36	GO:0051287	NAD binding
0.36	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.70	GO:0000785	chromatin
0.65	GO:0005654	nucleoplasm
0.51	GO:0005886	plasma membrane
0.38	GO:0000775	chromosome, centromeric region
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.1.1

GO:0016616

sp|Q2HXU8|CL12B_HUMAN
C-type lectin domain family 12 member B
Search

CLEC12B

0.97	Macrophage antigen H

0.74	GO:0002769	natural killer cell inhibitory signaling pathway
0.71	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.67	GO:2000272	negative regulation of receptor activity
0.36	GO:0050715	positive regulation of cytokine secretion
0.35	GO:0006898	receptor-mediated endocytosis

0.69	GO:0030246	carbohydrate binding
0.67	GO:0030547	receptor inhibitor activity
0.65	GO:0019903	protein phosphatase binding
0.33	GO:0042802	identical protein binding

0.64	GO:0009897	external side of plasma membrane
0.49	GO:0043234	protein complex
0.34	GO:0043235	receptor complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|Q2I0M4|LRC26_HUMAN
Leucine-rich repeat-containing protein 26
Search

LRRC26

0.96	Leucine-rich repeat-containing protein 26

0.78	GO:1903818	positive regulation of voltage-gated potassium channel activity
0.65	GO:0071805	potassium ion transmembrane transport
0.40	GO:0006468	protein phosphorylation
0.36	GO:0002376	immune system process
0.35	GO:0002718	regulation of cytokine production involved in immune response
0.35	GO:0045089	positive regulation of innate immune response
0.35	GO:0002764	immune response-regulating signaling pathway
0.34	GO:0006952	defense response

0.81	GO:0099103	channel activator activity
0.77	GO:0015459	potassium channel regulator activity
0.74	GO:0044325	ion channel binding
0.68	GO:0005249	voltage-gated potassium channel activity
0.40	GO:0004672	protein kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0001530	lipopolysaccharide binding

0.68	GO:0008076	voltage-gated potassium channel complex
0.45	GO:0070062	extracellular exosome
0.43	GO:0005856	cytoskeleton
0.36	GO:0005737	cytoplasm
0.35	GO:0046696	lipopolysaccharide receptor complex

sp|Q2I0M5|RSPO4_HUMAN
R-spondin-4
Search

RSPO4

0.96	LOW QUALITY PROTEIN: R-spondin-4

0.86	GO:0035878	nail development
0.43	GO:0016055	Wnt signaling pathway
0.43	GO:0030177	positive regulation of Wnt signaling pathway
0.38	GO:2000050	regulation of non-canonical Wnt signaling pathway
0.38	GO:0001974	blood vessel remodeling
0.37	GO:0002040	sprouting angiogenesis
0.37	GO:0060828	regulation of canonical Wnt signaling pathway

0.46	GO:0008201	heparin binding
0.37	GO:0005109	frizzled binding

0.41	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q2KHM9|MOONR_HUMAN
Protein moonraker
Search

0.85	GO:0007099	centriole replication
0.63	GO:0071539	protein localization to centrosome

0.30

GO:0005515

protein binding

0.63	GO:0034451	centriolar satellite
0.52	GO:0005829	cytosol
0.30	GO:0005814	centriole

sp|Q2KHN1|RN151_HUMAN
RING finger protein 151
Search

RNF151

0.97	LOW QUALITY PROTEIN: RING finger protein 151

0.57	GO:0016567	protein ubiquitination
0.40	GO:0007283	spermatogenesis
0.39	GO:0016055	Wnt signaling pathway
0.38	GO:0030154	cell differentiation
0.35	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.34	GO:0036503	ERAD pathway
0.34	GO:0030968	endoplasmic reticulum unfolded protein response
0.33	GO:0006364	rRNA processing
0.33	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process

0.62	GO:0008270	zinc ion binding
0.58	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0072572	poly-ADP-D-ribose binding
0.40	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:1990381	ubiquitin-specific protease binding
0.34	GO:0016874	ligase activity
0.33	GO:0031624	ubiquitin conjugating enzyme binding
0.32	GO:0051082	unfolded protein binding

0.49	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.34	GO:0032040	small-subunit processome
0.33	GO:0000151	ubiquitin ligase complex
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.32	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.34	EC:6	GO:0016874
0.58	KEGG:R03876	GO:0004842

sp|Q2KHR2|RFX7_HUMAN
DNA-binding protein RFX7
Search

RFX7

0.88	Regulatory factor X domain containing 2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0003700	DNA binding transcription factor activity

0.47

GO:0005634

nucleus

sp|Q2KHR3|QSER1_HUMAN
Glutamine and serine-rich protein 1
Search

QSER1

0.97	Glutamine and serine-rich protein 1

0.57

GO:0005509

calcium ion binding

0.55	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q2KHT3|CL16A_HUMAN
Protein CLEC16A
Search

CLEC16A

0.97	C-type lectin domain containing 16A

0.85	GO:1904766	negative regulation of macroautophagy by TORC1 signaling
0.83	GO:1901097	negative regulation of autophagosome maturation
0.83	GO:1901525	negative regulation of mitophagy
0.82	GO:1901098	positive regulation of autophagosome maturation
0.79	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.76	GO:1904263	positive regulation of TORC1 signaling
0.71	GO:0009267	cellular response to starvation
0.41	GO:0006914	autophagy

0.50	GO:0030246	carbohydrate binding
0.35	GO:0005515	protein binding

0.84	GO:0036020	endolysosome membrane
0.65	GO:0005794	Golgi apparatus
0.63	GO:0005829	cytosol

sp|Q2KHT4|GSG1_HUMAN
Germ cell-specific gene 1 protein
Search

GSG1

0.91	Germ cell-specific protein 1

0.36	GO:2000311	regulation of AMPA receptor activity
0.35	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity

0.49

GO:0070063

RNA polymerase binding

0.49	GO:0099146	intrinsic component of postsynaptic density membrane
0.49	GO:0099060	integral component of postsynaptic specialization membrane
0.47	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.36	GO:0030054	cell junction

sp|Q2KJY2|KI26B_HUMAN
Kinesin-like protein KIF26B
Search

KIF26B

0.86	Kinesin family member 26Ba

0.76	GO:0072092	ureteric bud invasion
0.74	GO:0007018	microtubule-based movement
0.67	GO:0030010	establishment of cell polarity
0.63	GO:0022409	positive regulation of cell-cell adhesion
0.45	GO:0001560	regulation of cell growth by extracellular stimulus
0.44	GO:0048484	enteric nervous system development
0.40	GO:0009968	negative regulation of signal transduction

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0016887	ATPase activity

0.62

GO:0005871

kinesin complex

0.49

GO:0016887

sp|Q2L4Q9|PRS53_HUMAN
Serine protease 53
Search

PRSS53

0.97	Serine protease 53

0.61	GO:0006508	proteolysis
0.48	GO:0007596	blood coagulation
0.35	GO:0048518	positive regulation of biological process
0.35	GO:0072376	protein activation cascade
0.35	GO:0006959	humoral immune response
0.35	GO:0048583	regulation of response to stimulus
0.35	GO:1900046	regulation of hemostasis
0.35	GO:0050818	regulation of coagulation
0.35	GO:0048609	multicellular organismal reproductive process
0.34	GO:0019953	sexual reproduction

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0005509	calcium ion binding
0.34	GO:0017080	sodium channel regulator activity
0.34	GO:0047058	vitamin-K-epoxide reductase (warfarin-insensitive) activity
0.34	GO:0047057	vitamin-K-epoxide reductase (warfarin-sensitive) activity
0.33	GO:0005537	mannose binding
0.32	GO:0003995	acyl-CoA dehydrogenase activity
0.32	GO:0050660	flavin adenine dinucleotide binding

0.39	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm
0.37	GO:0097223	sperm part
0.36	GO:0046658	anchored component of plasma membrane
0.36	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0043204	perikaryon
0.35	GO:0030425	dendrite
0.34	GO:0005887	integral component of plasma membrane

0.69

GO:0004252

sp|Q2LD37|K1109_HUMAN
Uncharacterized protein KIAA1109
Search

ADAD1-1

0.72	Adenosine deaminase domain-containing protein 1 isoform C

0.38	GO:0001558	regulation of cell growth
0.37	GO:0060612	adipose tissue development
0.37	GO:0051647	nucleus localization
0.37	GO:0030856	regulation of epithelial cell differentiation
0.37	GO:0045444	fat cell differentiation
0.36	GO:0019915	lipid storage
0.36	GO:0007283	spermatogenesis
0.34	GO:0006629	lipid metabolic process
0.33	GO:0006396	RNA processing

0.34	GO:0005515	protein binding
0.34	GO:0004000	adenosine deaminase activity
0.32	GO:0003723	RNA binding

0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:3.5.4.4

GO:0004000

sp|Q2M1K9|ZN423_HUMAN
Zinc finger protein 423
Search

ZNF521

0.81	Early hematopoietic zinc finger protein (Fragment)

0.48	GO:0048663	neuron fate commitment
0.46	GO:0030513	positive regulation of BMP signaling pathway
0.44	GO:0007219	Notch signaling pathway
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.47	GO:0019904	protein domain specific binding
0.35	GO:0046872	metal ion binding
0.31	GO:0042803	protein homodimerization activity
0.31	GO:0046982	protein heterodimerization activity

0.44	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q2M1P5|KIF7_HUMAN
Kinesin-like protein KIF7
Search

KIF7

0.94	Kinesin family member 7

0.74	GO:0007018	microtubule-based movement
0.40	GO:0045880	positive regulation of smoothened signaling pathway
0.40	GO:0045879	negative regulation of smoothened signaling pathway
0.40	GO:0060976	coronary vasculature development
0.40	GO:0035904	aorta development
0.39	GO:0003279	cardiac septum development

0.75	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042623	ATPase activity, coupled
0.38	GO:0042802	identical protein binding

0.62	GO:0005929	cilium
0.55	GO:0005871	kinesin complex
0.38	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005815	microtubule organizing center

sp|Q2M1V0|ISX_HUMAN
Intestine-specific homeobox
Search

ISX

0.97	Pancreas-intestine homeodomain transcription factor

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0042705	ocellus photoreceptor cell differentiation
0.43	GO:1901738	regulation of vitamin A metabolic process
0.42	GO:0042052	rhabdomere development
0.42	GO:1904479	negative regulation of intestinal absorption
0.40	GO:0006366	transcription by RNA polymerase II
0.39	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:1902679	negative regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.42	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0003690	double-stranded DNA binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q2M1Z3|RHG31_HUMAN
Rho GTPase-activating protein 31
Search

ARHGAP31

0.96	Rho GTPase-activating protein 31

0.60	GO:0007165	signal transduction
0.60	GO:0043547	positive regulation of GTPase activity
0.37	GO:0051056	regulation of small GTPase mediated signal transduction
0.37	GO:0015031	protein transport

0.61	GO:0017124	SH3 domain binding
0.60	GO:0005096	GTPase activator activity
0.40	GO:0035091	phosphatidylinositol binding

0.63	GO:0030027	lamellipodium
0.40	GO:0005925	focal adhesion
0.40	GO:0005622	intracellular
0.32	GO:0043226	organelle
0.32	GO:0071944	cell periphery
0.30	GO:0016020	membrane

sp|Q2M218|ZN630_HUMAN
Zinc finger protein 630
Search

ZNF182

0.49	Zinc finger protein 21

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.48	GO:0006366	transcription by RNA polymerase II
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0006468	protein phosphorylation

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.50	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.47	GO:0005730	nucleolus
0.36	GO:0005654	nucleoplasm
0.36	GO:0005856	cytoskeleton
0.34	GO:0005829	cytosol

sp|Q2M238|RN3P1_HUMAN
Putative RRN3-like protein RRN3P1
Search

sp|Q2M243|CCD27_HUMAN
Coiled-coil domain-containing protein 27
Search

CCDC27

0.97	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 27

0.49	GO:0006915	apoptotic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:0010468	regulation of gene expression

0.48	GO:0044212	transcription regulatory region DNA binding
0.43	GO:0003700	DNA binding transcription factor activity

0.43	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q2M296|MTHSD_HUMAN
Methenyltetrahydrofolate synthase domain-containing protein
Search

MTHFSD

0.96	Methenyltetrahydrofolate synthetase domain containing

0.50	GO:0008298	intracellular mRNA localization
0.31	GO:0055085	transmembrane transport

0.56	GO:0003723	RNA binding
0.34	GO:0016874	ligase activity
0.32	GO:0022857	transmembrane transporter activity

0.37	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.34

GO:0016874

sp|Q2M2D7|TBC28_HUMAN
TBC1 domain family member 28
Search

TBC1D26

0.97	TBC1 domain family member 28

0.85	GO:0031338	regulation of vesicle fusion
0.84	GO:0090630	activation of GTPase activity
0.69	GO:0006886	intracellular protein transport

0.81	GO:0017137	Rab GTPase binding
0.76	GO:0005096	GTPase activator activity

0.67	GO:0012505	endomembrane system
0.45	GO:0005622	intracellular

sp|Q2M2E3|ODFP4_HUMAN
Outer dense fiber protein 4
Search

ODF4

0.93	LOW QUALITY PROTEIN: outer dense fiber protein 4

0.48	GO:0007283	spermatogenesis
0.45	GO:0030154	cell differentiation
0.44	GO:0007275	multicellular organism development

0.41

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q2M2E5|CE064_HUMAN
Uncharacterized protein C5orf64
Search

sp|Q2M2H8|MGAL_HUMAN
Probable maltase-glucoamylase 2
Search

MGAM2

0.64	Maltase-glucoamylase, intestinal

0.60

GO:0005975

carbohydrate metabolic process

0.69	GO:0030246	carbohydrate binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.30

GO:0044425

membrane part

0.66

GO:0004553

sp|Q2M2I3|FA83E_HUMAN
Protein FAM83E
Search

0.58	GO:1902480	protein localization to mitotic spindle
0.54	GO:0030509	BMP signaling pathway
0.54	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.54	GO:0001837	epithelial to mesenchymal transition
0.54	GO:0051310	metaphase plate congression
0.52	GO:0070372	regulation of ERK1 and ERK2 cascade
0.52	GO:0008283	cell proliferation
0.51	GO:0032006	regulation of TOR signaling
0.51	GO:0042176	regulation of protein catabolic process
0.50	GO:0016477	cell migration

0.73	GO:0019901	protein kinase binding
0.53	GO:0019894	kinesin binding
0.49	GO:0008017	microtubule binding
0.39	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.36	GO:1990254	keratin filament binding
0.32	GO:0003676	nucleic acid binding

0.55	GO:0097431	mitotic spindle pole
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.35	GO:0045095	keratin filament
0.30	GO:0031224	intrinsic component of membrane

sp|Q2M2I5|K1C24_HUMAN
Keratin, type I cytoskeletal 24
Search

KRT24

0.96	Adult keratin XAK-C

0.42	GO:0030216	keratinocyte differentiation
0.41	GO:0018149	peptide cross-linking
0.38	GO:0007010	cytoskeleton organization
0.37	GO:0045103	intermediate filament-based process
0.35	GO:0012501	programmed cell death
0.35	GO:0071277	cellular response to calcium ion
0.34	GO:0002064	epithelial cell development
0.34	GO:0097435	supramolecular fiber organization

0.62	GO:0005198	structural molecule activity
0.37	GO:0097110	scaffold protein binding
0.33	GO:0008092	cytoskeletal protein binding

0.79	GO:0005882	intermediate filament
0.41	GO:0001533	cornified envelope
0.39	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.33	GO:0036338	viral membrane

sp|Q2M2I8|AAK1_HUMAN
AP2-associated protein kinase 1
Search

AAK1

0.86	AP2-associated protein kinase 1

0.67	GO:2000369	regulation of clathrin-dependent endocytosis
0.64	GO:0045747	positive regulation of Notch signaling pathway
0.63	GO:0006468	protein phosphorylation
0.60	GO:0050821	protein stabilization
0.57	GO:0032880	regulation of protein localization
0.41	GO:0006897	endocytosis
0.35	GO:0061024	membrane organization

0.68	GO:0035612	AP-2 adaptor complex binding
0.64	GO:0005112	Notch binding
0.63	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0043195	terminal bouton
0.44	GO:0005905	clathrin-coated pit
0.44	GO:0031252	cell leading edge
0.43	GO:0019897	extrinsic component of plasma membrane
0.42	GO:0030136	clathrin-coated vesicle
0.37	GO:0071439	clathrin complex
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q2M2W7|CQ058_HUMAN
UPF0450 protein C17orf58
Search

0.11	Procollagen C-endopeptidase enhancer (Fragment)

0.66

GO:0005576

extracellular region

sp|Q2M2Z5|KIZ_HUMAN
Centrosomal protein kizuna
Search

KIZ

0.96	Centrosomal protein kizuna

0.80

GO:0007051

spindle organization

0.58

GO:0019901

protein kinase binding

0.78	GO:0005813	centrosome
0.41	GO:0005737	cytoplasm
0.39	GO:0042995	cell projection
0.30	GO:0031224	intrinsic component of membrane

sp|Q2M329|CCD96_HUMAN
Coiled-coil domain-containing protein 96
Search

CCDC96

0.88	Coiled-coil domain-containing protein 96

0.40	GO:0070932	histone H3 deacetylation
0.38	GO:0007166	cell surface receptor signaling pathway
0.37	GO:0006468	protein phosphorylation
0.36	GO:0005975	carbohydrate metabolic process
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0006413	translational initiation
0.34	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.40	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.38	GO:0004888	transmembrane signaling receptor activity
0.37	GO:0004672	protein kinase activity
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0004527	exonuclease activity
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0004519	endonuclease activity

0.65	GO:0005815	microtubule organizing center
0.44	GO:0005737	cytoplasm
0.40	GO:0031514	motile cilium
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0032041

sp|Q2M385|MPEG1_HUMAN
Macrophage-expressed gene 1 protein
Search

MPEG1

0.97	Macrophage expressed gene 1

0.38	GO:0042742	defense response to bacterium
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0065009	regulation of molecular function

0.33

GO:0005085

guanyl-nucleotide exchange factor activity

0.31	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q2M389|WASC4_HUMAN
WASH complex subunit 4
Search

WASHC4

0.96	WASH complex subunit 4

0.54	GO:0016197	endosomal transport
0.50	GO:0007032	endosome organization
0.35	GO:0015031	protein transport

0.84	GO:0071203	WASH complex
0.53	GO:0005768	endosome
0.49	GO:0005654	nucleoplasm
0.38	GO:0031083	BLOC-1 complex
0.30	GO:0016020	membrane

sp|Q2M3A8|MRAS1_HUMAN
Putative uncharacterized protein MRGPRG-AS1
Search

sp|Q2M3C6|TM266_HUMAN
Transmembrane protein 266
Search

TMEM266

0.45	Transmembrane protein 266

0.53	GO:0034220	ion transmembrane transport
0.31	GO:0071804	cellular potassium ion transport

0.60	GO:0005216	ion channel activity
0.31	GO:0015079	potassium ion transmembrane transporter activity

0.51	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q2M3C7|SPKAP_HUMAN
A-kinase anchor protein SPHKAP
Search

SPHKAP

0.97	A-kinase anchor protein SPHKAP

0.56	GO:0016310	phosphorylation
0.46	GO:0010738	regulation of protein kinase A signaling

0.58	GO:0016301	kinase activity
0.49	GO:0051018	protein kinase A binding

0.42	GO:0070062	extracellular exosome
0.41	GO:0030018	Z disc
0.39	GO:0005739	mitochondrion

sp|Q2M3D2|EX3L2_HUMAN
Exocyst complex component 3-like protein 2
Search

EXOC3L2

0.96	Exocyst complex component 3 like 2

0.77	GO:0006887	exocytosis
0.56	GO:0051601	exocyst localization

0.52

GO:0000149

SNARE binding

0.79

GO:0000145

exocyst

sp|Q2M3G0|ABCB5_HUMAN
ATP-binding cassette sub-family B member 5
Search

0.44	Multidrug resistance protein 1

0.54	GO:0055085	transmembrane transport
0.51	GO:1901557	response to fenofibrate
0.50	GO:1903413	cellular response to bile acid
0.49	GO:0061092	positive regulation of phospholipid translocation
0.49	GO:0032782	bile acid secretion
0.48	GO:0032376	positive regulation of cholesterol transport
0.47	GO:0048058	compound eye corneal lens development
0.46	GO:0055088	lipid homeostasis
0.45	GO:0045332	phospholipid translocation
0.43	GO:1901998	toxin transport

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.44	GO:0019534	toxin transmembrane transporter activity
0.43	GO:0015562	efflux transmembrane transporter activity
0.42	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.30	GO:0042910	xenobiotic transmembrane transporter activity
0.30	GO:0015238	drug transmembrane transporter activity

0.49	GO:0046581	intercellular canaliculus
0.46	GO:0005925	focal adhesion
0.46	GO:0016324	apical plasma membrane
0.43	GO:0015629	actin cytoskeleton
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.40	GO:0005887	integral component of plasma membrane

sp|Q2M3G4|SHRM1_HUMAN
Protein Shroom1
Search

SHROOM1

0.97	Shroom family member 1 (Predicted)

0.62	GO:0051017	actin filament bundle assembly
0.57	GO:0000902	cell morphogenesis

0.78	GO:0051015	actin filament binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032555	purine ribonucleotide binding

0.64	GO:0016460	myosin II complex
0.39	GO:0005874	microtubule
0.34	GO:0005737	cytoplasm

sp|Q2M3M2|SC5A9_HUMAN
Sodium/glucose cotransporter 4
Search

SLC5A9

0.97	Sodium/glucose cotransporter 4

0.55	GO:0055085	transmembrane transport
0.50	GO:0015758	glucose transport
0.47	GO:0006814	sodium ion transport

0.57

GO:0022857

transmembrane transporter activity

0.44	GO:0005887	integral component of plasma membrane
0.39	GO:0070062	extracellular exosome

sp|Q2M3R5|S35G1_HUMAN
Solute carrier family 35 member G1
Search

SLC35G1

0.90	Transmembrane protein 20

0.61	GO:1990034	calcium ion export across plasma membrane
0.55	GO:0051480	regulation of cytosolic calcium ion concentration

0.34

GO:0005515

protein binding

0.50	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q2M3T9|HYAL4_HUMAN
Hyaluronidase-4
Search

HYAL4

0.72	Hyaluronidase

0.62	GO:0030207	chondroitin sulfate catabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.42	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.39	GO:0042117	monocyte activation
0.39	GO:0010764	negative regulation of fibroblast migration
0.39	GO:0060586	multicellular organismal iron ion homeostasis
0.39	GO:2000484	positive regulation of interleukin-8 secretion
0.39	GO:0030214	hyaluronan catabolic process
0.39	GO:0071493	cellular response to UV-B
0.38	GO:2000778	positive regulation of interleukin-6 secretion

0.85	GO:0004415	hyalurononglucosaminidase activity
0.39	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity
0.39	GO:0033906	hyaluronoglucuronidase activity
0.39	GO:0104005	hijacked molecular function
0.38	GO:0050431	transforming growth factor beta binding
0.38	GO:0001105	RNA polymerase II transcription coactivator activity
0.38	GO:0030971	receptor tyrosine kinase binding
0.38	GO:0005540	hyaluronic acid binding
0.35	GO:0005525	GTP binding

0.53	GO:0009986	cell surface
0.38	GO:0005902	microvillus
0.38	GO:0046658	anchored component of plasma membrane
0.37	GO:0016324	apical plasma membrane
0.37	GO:0030139	endocytic vesicle
0.37	GO:0098857	membrane microdomain
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005764	lysosome
0.37	GO:0090575	RNA polymerase II transcription factor complex
0.37	GO:0098552	side of membrane

0.85

EC:3.2.1.35

GO:0004415

sp|Q2M3V2|SWAHA_HUMAN
Ankyrin repeat domain-containing protein SOWAHA
Search

SOWAHA

0.97	Ankyrin repeat domain-containing protein SOWAHA

sp|Q2M3W8|ZN181_HUMAN
Zinc finger protein 181
Search

ZNF181

0.66	Zinc finger domain-containing protein (Fragment)

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0043230	extracellular organelle
0.34	GO:0005615	extracellular space
0.32	GO:0012505	endomembrane system
0.32	GO:0031975	envelope
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|Q2M3X9|ZN674_HUMAN
Zinc finger protein 674
Search

0.71	Zinc finger protein 84

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.46	GO:0006366	transcription by RNA polymerase II
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0051607	defense response to virus
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.48	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.43	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0031981	nuclear lumen
0.42	GO:0045111	intermediate filament cytoskeleton
0.40	GO:0005829	cytosol
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q2M5E4|RGS21_HUMAN
Regulator of G-protein signaling 21
Search

RGS21

0.91	regulator of G-protein signaling 2

0.71	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.70	GO:0043547	positive regulation of GTPase activity
0.59	GO:0009968	negative regulation of signal transduction
0.53	GO:0010519	negative regulation of phospholipase activity
0.53	GO:0060087	relaxation of vascular smooth muscle
0.53	GO:0060452	positive regulation of cardiac muscle contraction
0.53	GO:0055119	relaxation of cardiac muscle
0.53	GO:0010614	negative regulation of cardiac muscle hypertrophy
0.52	GO:0043949	regulation of cAMP-mediated signaling
0.50	GO:0050873	brown fat cell differentiation

0.70	GO:0005096	GTPase activator activity
0.61	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0048487	beta-tubulin binding
0.34	GO:0005092	GDP-dissociation inhibitor activity
0.34	GO:0005516	calmodulin binding
0.32	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding

0.48	GO:0005829	cytosol
0.47	GO:0009898	cytoplasmic side of plasma membrane
0.45	GO:0005634	nucleus
0.38	GO:0043005	neuron projection
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0043025	neuronal cell body
0.35	GO:0098793	presynapse
0.35	GO:0098794	postsynapse
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q2MJR0|SPRE3_HUMAN
Sprouty-related, EVH1 domain-containing protein 3
Search

SPRED3

0.91	Sprouty-related, EVH1 domain-containing protein 3

0.69	GO:0007275	multicellular organism development
0.69	GO:0009966	regulation of signal transduction
0.46	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.43	GO:0023057	negative regulation of signaling
0.43	GO:0010648	negative regulation of cell communication
0.43	GO:0048585	negative regulation of response to stimulus
0.42	GO:0090311	regulation of protein deacetylation
0.42	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.41	GO:2001022	positive regulation of response to DNA damage stimulus
0.40	GO:0023056	positive regulation of signaling

0.49	GO:0005173	stem cell factor receptor binding
0.41	GO:0030291	protein serine/threonine kinase inhibitor activity
0.41	GO:0019901	protein kinase binding
0.38	GO:0019902	phosphatase binding

0.39	GO:0031410	cytoplasmic vesicle
0.37	GO:0005886	plasma membrane
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q2MKA7|RSPO1_HUMAN
R-spondin-1
Search

RSPO1

0.97	Ovarian R-spondin member 1

0.83	GO:0002090	regulation of receptor internalization
0.81	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.73	GO:0001934	positive regulation of protein phosphorylation
0.49	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.48	GO:0001525	angiogenesis
0.46	GO:2000052	positive regulation of non-canonical Wnt signaling pathway
0.45	GO:0016055	Wnt signaling pathway
0.44	GO:2000254	regulation of male germ cell proliferation
0.43	GO:0007140	male meiotic nuclear division
0.40	GO:0033337	dorsal fin development

0.77	GO:0001664	G-protein coupled receptor binding
0.47	GO:0008201	heparin binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0004252	serine-type endopeptidase activity

0.44	GO:0005794	Golgi apparatus
0.43	GO:0005829	cytosol
0.42	GO:0005576	extracellular region
0.39	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

GO:0004252

sp|Q2MV58|TECT1_HUMAN
Tectonic-1
Search

TCTN1

0.89	Tectonic-1 isoform B

0.87	GO:0021956	central nervous system interneuron axonogenesis
0.86	GO:1904491	protein localization to ciliary transition zone
0.86	GO:0021523	somatic motor neuron differentiation
0.85	GO:0021904	dorsal/ventral neural tube patterning
0.83	GO:0008589	regulation of smoothened signaling pathway
0.82	GO:0001841	neural tube formation
0.80	GO:0021537	telencephalon development
0.78	GO:0060271	cilium assembly
0.75	GO:0001701	in utero embryonic development
0.43	GO:0007224	smoothened signaling pathway

0.37	GO:0005515	protein binding
0.34	GO:0098772	molecular function regulator
0.33	GO:0046872	metal ion binding
0.32	GO:0003735	structural constituent of ribosome

0.84	GO:0036038	MKS complex
0.71	GO:0005615	extracellular space
0.41	GO:0005856	cytoskeleton
0.39	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.34	GO:0000793	condensed chromosome
0.34	GO:0044427	chromosomal part
0.33	GO:0060170	ciliary membrane
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:1903561	extracellular vesicle

sp|Q2NKJ3|CTC1_HUMAN
CST complex subunit CTC1
Search

CTC1

0.91	CST telomere replication complex component 1

0.76	GO:0048539	bone marrow development
0.74	GO:0071425	hematopoietic stem cell proliferation
0.74	GO:0090399	replicative senescence
0.73	GO:0032211	negative regulation of telomere maintenance via telomerase
0.73	GO:0045740	positive regulation of DNA replication
0.73	GO:0010833	telomere maintenance via telomere lengthening
0.73	GO:0048536	spleen development
0.72	GO:0048146	positive regulation of fibroblast proliferation
0.72	GO:0048538	thymus development
0.71	GO:0035264	multicellular organism growth

0.76	GO:0098505	G-rich strand telomeric DNA binding
0.37	GO:0005515	protein binding

0.74	GO:1990879	CST complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q2NKQ1|SGSM1_HUMAN
Small G protein signaling modulator 1
Search

SGSM1

0.75	Small G protein signaling modulator 1

0.76	GO:0043547	positive regulation of GTPase activity
0.52	GO:0031338	regulation of vesicle fusion
0.47	GO:0046907	intracellular transport
0.46	GO:0034613	cellular protein localization
0.44	GO:0015031	protein transport
0.38	GO:0048193	Golgi vesicle transport
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II

0.76	GO:0005096	GTPase activator activity
0.60	GO:0017137	Rab GTPase binding

0.55	GO:0030659	cytoplasmic vesicle membrane
0.50	GO:0005829	cytosol
0.45	GO:0012505	endomembrane system
0.40	GO:0042470	melanosome
0.35	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q2NKX8|ERC6L_HUMAN
DNA excision repair protein ERCC-6-like
Search

ERCC6L

0.86	ERCC excision repair 6 like, spindle assembly checkpoint helicase

0.39	GO:0051301	cell division
0.38	GO:0007049	cell cycle
0.36	GO:0007059	chromosome segregation
0.35	GO:0051276	chromosome organization
0.35	GO:0016539	intein-mediated protein splicing

0.65	GO:0015616	DNA translocase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004386	helicase activity
0.36	GO:0003677	DNA binding
0.35	GO:0005515	protein binding

0.41	GO:0000777	condensed chromosome kinetochore
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q2NKX9|CB068_HUMAN
UPF0561 protein C2orf68
Search

sp|Q2NL67|PARP6_HUMAN
Poly [ADP-ribose] polymerase 6
Search

PARP6

0.57	Poly [ADP-ribose] polymerase

0.35	GO:0012501	programmed cell death
0.34	GO:0006757	ATP generation from ADP
0.34	GO:0006090	pyruvate metabolic process
0.34	GO:0016052	carbohydrate catabolic process
0.34	GO:0019362	pyridine nucleotide metabolic process

0.80	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.35	GO:0045296	cadherin binding
0.35	GO:0004743	pyruvate kinase activity
0.33	GO:0003723	RNA binding

0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.80

GO:0003950

sp|Q2NL68|PRSR3_HUMAN
Proline and serine-rich protein 3
Search

PROSER3

0.97	Proline and serine-rich protein 3

0.62

GO:0035091

phosphatidylinositol binding

sp|Q2NL82|TSR1_HUMAN
Pre-rRNA-processing protein TSR1 homolog
Search

TSR1

0.94	TSR1, ribosome maturation factor

0.67	GO:0042254	ribosome biogenesis
0.49	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.48	GO:0016072	rRNA metabolic process
0.46	GO:0034470	ncRNA processing

0.57	GO:0034511	U3 snoRNA binding
0.48	GO:0003924	GTPase activity
0.47	GO:0032550	purine ribonucleoside binding
0.47	GO:0019001	guanyl nucleotide binding
0.41	GO:0032553	ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.55	GO:0030688	preribosome, small subunit precursor

sp|Q2NL98|VMAC_HUMAN
Vimentin-type intermediate filament-associated coiled-coil protein
Search

VMAC

0.97	vimentin-type intermediate filament-associated coiled-coil protein-like

0.46

GO:0005515

protein binding

0.71	GO:0045098	type III intermediate filament
0.49	GO:0005737	cytoplasm

sp|Q2PPJ7|RGPA2_HUMAN
Ral GTPase-activating protein subunit alpha-2
Search

RALGAPA2

0.95	Ral GTPase activating protein catalytic alpha subunit 2

0.75	GO:0043547	positive regulation of GTPase activity
0.74	GO:0051056	regulation of small GTPase mediated signal transduction
0.42	GO:0032484	Ral protein signal transduction
0.41	GO:0060178	regulation of exocyst localization

0.76	GO:0005096	GTPase activator activity
0.40	GO:0046982	protein heterodimerization activity
0.33	GO:0003676	nucleic acid binding

0.61	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.38	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q2PZI1|D19L1_HUMAN
Probable C-mannosyltransferase DPY19L1
Search

DPY19L1

0.96	Dpy-19 like 1

0.64	GO:0018317	protein C-linked glycosylation via tryptophan
0.60	GO:0035268	protein mannosylation
0.58	GO:0007286	spermatid development

0.56

GO:0000030

mannosyltransferase activity

0.62	GO:0005637	nuclear inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.56

GO:0000030

sp|Q2Q1W2|LIN41_HUMAN
E3 ubiquitin-protein ligase TRIM71
Search

TRIM71

0.87	Tripartite motif-containing protein 71

0.75	GO:0061158	3'-UTR-mediated mRNA destabilization
0.72	GO:0035196	production of miRNAs involved in gene silencing by miRNA
0.68	GO:0010586	miRNA metabolic process
0.68	GO:2000637	positive regulation of gene silencing by miRNA
0.66	GO:0035278	miRNA mediated inhibition of translation
0.66	GO:0072089	stem cell proliferation
0.65	GO:0051865	protein autoubiquitination
0.65	GO:2000177	regulation of neural precursor cell proliferation
0.65	GO:0001843	neural tube closure
0.64	GO:0008543	fibroblast growth factor receptor signaling pathway

0.74	GO:0035198	miRNA binding
0.73	GO:0030371	translation repressor activity
0.63	GO:0008270	zinc ion binding
0.60	GO:0061630	ubiquitin protein ligase activity

0.69

GO:0000932

P-body

sp|Q2QD12|RPEL1_HUMAN
Ribulose-phosphate 3-epimerase-like protein 1
Search

RPE

0.42	Ribulose-phosphate 3-epimerase

0.67	GO:0006098	pentose-phosphate shunt
0.60	GO:0005975	carbohydrate metabolic process
0.43	GO:0060271	cilium assembly
0.43	GO:0044282	small molecule catabolic process
0.41	GO:1901575	organic substance catabolic process

0.73	GO:0004750	ribulose-phosphate 3-epimerase activity
0.51	GO:0046872	metal ion binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0048029	monosaccharide binding

0.43	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0043231	intracellular membrane-bounded organelle

0.73	EC:5.1.3.1	GO:0004750
0.73	KEGG:R01529	GO:0004750

sp|Q2QGD7|ZXDC_HUMAN
Zinc finger protein ZXDC
Search

ZXDC

0.97	Zinc finger protein ZXDC

0.51	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0006351	transcription, DNA-templated

0.60	GO:0070742	C2H2 zinc finger domain binding
0.60	GO:0030275	LRR domain binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0003700	DNA binding transcription factor activity
0.37	GO:0016153	urocanate hydratase activity
0.34	GO:0046872	metal ion binding

0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.37	EC:4.2.1.49	GO:0016153
0.37	KEGG:R02914	GO:0016153

sp|Q2QL34|MP17L_HUMAN
Mpv17-like protein
Search

0.10	MPV17 mitochondrial inner membrane protein-like

0.47	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process
0.46	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.41	GO:0072593	reactive oxygen species metabolic process

0.41

GO:0005102

receptor binding

0.44	GO:0005739	mitochondrion
0.43	GO:0005777	peroxisome
0.41	GO:0031903	microbody membrane
0.30	GO:0016021	integral component of membrane

sp|Q2T9J0|TYSD1_HUMAN
Peroxisomal leader peptide-processing protease
Search

TYSND1

0.96	Trypsin domain containing 1

0.86	GO:0031998	regulation of fatty acid beta-oxidation
0.78	GO:0051260	protein homooligomerization
0.75	GO:0016485	protein processing

0.84	GO:0002020	protease binding
0.69	GO:0004252	serine-type endopeptidase activity
0.40	GO:0042802	identical protein binding

0.76	GO:0042579	microbody
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|Q2T9K0|TMM44_HUMAN
Transmembrane protein 44
Search

TMEM44

0.83	Transmembrane protein 44

0.56	GO:0015189	L-lysine transmembrane transporter activity
0.54	GO:0015181	arginine transmembrane transporter activity

0.53	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

sp|Q2T9L4|CO059_HUMAN
UPF0583 protein C15orf59
Search

0.57	GO:0045793	positive regulation of cell size
0.52	GO:0045727	positive regulation of translation

sp|Q2TAA2|IAH1_HUMAN
Isoamyl acetate-hydrolyzing esterase 1 homolog
Search

IAH1

0.95	Isoamyl acetate-hydrolyzing esterase 1

0.61

GO:0016042

lipid catabolic process

0.51

GO:0016788

hydrolase activity, acting on ester bonds

0.55

GO:0070062

extracellular exosome

0.51

GO:0016788

sp|Q2TAA5|ALG11_HUMAN
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Search

ALG11

0.47	Asparagine-linked glycosylation protein 11

0.78	GO:0097502	mannosylation
0.52	GO:0033577	protein glycosylation in endoplasmic reticulum
0.49	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process

0.85

GO:0004377

GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.4.1.131

GO:0004377

sp|Q2TAA8|TXIP1_HUMAN
Translin-associated factor X-interacting protein 1
Search

TSNAXIP1

0.97	LOW QUALITY PROTEIN: translin-associated factor X-interacting protein 1

0.43	GO:0007283	spermatogenesis
0.41	GO:0030154	cell differentiation
0.41	GO:0007275	multicellular organism development

0.36	GO:0005515	protein binding
0.35	GO:0005509	calcium ion binding

0.48

GO:0005737

cytoplasm

sp|Q2TAC2|CCD57_HUMAN
Coiled-coil domain-containing protein 57
Search

CCDC57

0.97	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 57

0.57

GO:0005515

protein binding

sp|Q2TAC6|KIF19_HUMAN
Kinesin-like protein KIF19
Search

KIF19

0.96	Kinesin-1 heavy chain

0.74	GO:0007018	microtubule-based movement
0.64	GO:0060404	axonemal microtubule depolymerization
0.63	GO:0070462	plus-end specific microtubule depolymerization
0.37	GO:0060271	cilium assembly
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0001731	formation of translation preinitiation complex
0.34	GO:0006446	regulation of translational initiation

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0016887	ATPase activity
0.35	GO:0004930	G-protein coupled receptor activity
0.34	GO:0031369	translation initiation factor binding
0.33	GO:0003723	RNA binding
0.32	GO:0005509	calcium ion binding

0.65	GO:0005874	microtubule
0.57	GO:0005930	axoneme
0.52	GO:0005871	kinesin complex
0.37	GO:0031514	motile cilium
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0031224	intrinsic component of membrane

0.47

GO:0016887

sp|Q2TAK8|MUM1_HUMAN
PWWP domain-containing protein MUM1
Search

MUM1

0.96	Mutated melanoma-associated antigen 1

0.71	GO:0006325	chromatin organization
0.64	GO:0006281	DNA repair
0.35	GO:0055114	oxidation-reduction process
0.33	GO:0006468	protein phosphorylation

0.82	GO:0031491	nucleosome binding
0.39	GO:0048038	quinone binding
0.38	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.38	GO:0051539	4 iron, 4 sulfur cluster binding
0.36	GO:0005515	protein binding
0.35	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome

0.38

EC:1.6.5.3

GO:0008137

sp|Q2TAL5|SMTL2_HUMAN
Smoothelin-like protein 2
Search

SMTNL2

0.96	Smoothelin like 2

0.68	GO:0043009	chordate embryonic development
0.57	GO:0060452	positive regulation of cardiac muscle contraction
0.56	GO:0003085	negative regulation of systemic arterial blood pressure
0.42	GO:0006939	smooth muscle contraction
0.41	GO:0007517	muscle organ development

0.65	GO:0003779	actin binding
0.43	GO:0008307	structural constituent of muscle
0.36	GO:0003677	DNA binding

0.40	GO:0015629	actin cytoskeleton
0.34	GO:0005737	cytoplasm

sp|Q2TAL6|VWC2_HUMAN
Brorin
Search

VWC2

0.94	von Willebrand factor C domain containing 2

0.79	GO:0030514	negative regulation of BMP signaling pathway
0.76	GO:0045666	positive regulation of neuron differentiation
0.70	GO:0010811	positive regulation of cell-substrate adhesion
0.49	GO:0030900	forebrain development

0.34

GO:0005515

protein binding

0.81	GO:0032281	AMPA glutamate receptor complex
0.73	GO:0005614	interstitial matrix
0.68	GO:0005615	extracellular space
0.68	GO:0005604	basement membrane
0.43	GO:0045202	synapse
0.43	GO:0030054	cell junction

sp|Q2TAL8|QRIC1_HUMAN
Glutamine-rich protein 1
Search

QRICH1

0.97	Glutamine-rich protein 1

0.56	GO:0007010	cytoskeleton organization
0.55	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0007275	multicellular organism development
0.55	GO:0022604	regulation of cell morphogenesis

0.57	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.46	GO:0003677	DNA binding
0.36	GO:0005515	protein binding

0.70	GO:0005654	nucleoplasm
0.42	GO:0005737	cytoplasm

sp|Q2TAM9|TUSC1_HUMAN
Tumor suppressor candidate gene 1 protein
Search

sp|Q2TAP0|GOG7B_HUMAN
Golgin subfamily A member 7B
Search

GOLGA7B

0.97	Golgi autoantigen, golgin subfamily a, 7B

0.85	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.82	GO:0018345	protein palmitoylation
0.79	GO:0072659	protein localization to plasma membrane
0.69	GO:0090150	establishment of protein localization to membrane
0.67	GO:0006893	Golgi to plasma membrane transport
0.63	GO:0050821	protein stabilization
0.62	GO:0015031	protein transport
0.60	GO:0046907	intracellular transport
0.39	GO:0043312	neutrophil degranulation

0.69	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.40	GO:0008376	acetylgalactosaminyltransferase activity
0.35	GO:0005515	protein binding

0.83	GO:0002178	palmitoyltransferase complex
0.65	GO:0005795	Golgi stack
0.64	GO:0031228	intrinsic component of Golgi membrane
0.41	GO:0070062	extracellular exosome
0.40	GO:1904724	tertiary granule lumen
0.30	GO:0016021	integral component of membrane

0.69

EC:2.3.1.225

GO:0019706

sp|Q2TAY7|SMU1_HUMAN
WD40 repeat-containing protein SMU1
Search

SMU1

0.94	DNA replication regulator and spliceosomal factor

0.80	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.70	GO:0008380	RNA splicing
0.67	GO:0006397	mRNA processing
0.45	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.40	GO:0006468	protein phosphorylation

0.48	GO:0016905	myosin heavy chain kinase activity
0.45	GO:0031683	G-protein beta/gamma-subunit complex binding
0.41	GO:0003924	GTPase activity
0.40	GO:0032550	purine ribonucleoside binding
0.40	GO:0019001	guanyl nucleotide binding
0.40	GO:0004871	signal transducer activity
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0016607	nuclear speck
0.70	GO:0005681	spliceosomal complex
0.47	GO:0005737	cytoplasm

0.48

EC:2.7.11.7

GO:0016905

sp|Q2TAZ0|ATG2A_HUMAN
Autophagy-related protein 2 homolog A
Search

ATG2A

0.89	Autophagy-related protein 2 like protein A

0.77	GO:0006914	autophagy
0.50	GO:0061726	mitochondrion disassembly
0.48	GO:0007033	vacuole organization
0.45	GO:0070925	organelle assembly
0.32	GO:0055085	transmembrane transport
0.32	GO:0006508	proteolysis

0.35	GO:0005515	protein binding
0.33	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity

0.51	GO:0005829	cytosol
0.49	GO:0000407	phagophore assembly site
0.48	GO:0005634	nucleus
0.47	GO:0019898	extrinsic component of membrane
0.39	GO:0005811	lipid droplet
0.37	GO:0098805	whole membrane
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q2TB10|ZN800_HUMAN
Zinc finger protein 800
Search

ZNF800

0.97	Zinc finger protein 800 (Predicted)

0.34	GO:0097659	nucleic acid-templated transcription
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0010467	gene expression
0.33	GO:0034645	cellular macromolecule biosynthetic process

0.50	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding

0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q2TB18|ASTE1_HUMAN
Protein asteroid homolog 1
Search

ASTE1

0.97	Asteroid homolog 1

0.64	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.64	GO:0004518	nuclease activity
0.36	GO:0005515	protein binding

0.64

GO:0004518

sp|Q2TB90|HKDC1_HUMAN
Putative hexokinase HKDC1
Search

HK1

0.44	Hexokinase domain containing 1

0.82	GO:0001678	cellular glucose homeostasis
0.74	GO:0046835	carbohydrate phosphorylation
0.70	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.35	GO:0051156	glucose 6-phosphate metabolic process
0.30	GO:0005996	monosaccharide metabolic process

0.83	GO:0005536	glucose binding
0.79	GO:0004396	hexokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol

0.79

EC:2.7.1.1

GO:0004396

sp|Q2TBA0|KLH40_HUMAN
Kelch-like protein 40
Search

KLHL40

0.97	Kelch repeat and BTB domain-containing protein 5

0.85	GO:0048741	skeletal muscle fiber development
0.77	GO:0031397	negative regulation of protein ubiquitination
0.58	GO:0035914	skeletal muscle cell differentiation
0.55	GO:0045214	sarcomere organization
0.49	GO:0036268	swimming
0.49	GO:0016567	protein ubiquitination
0.49	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.48	GO:2000291	regulation of myoblast proliferation
0.47	GO:2001014	regulation of skeletal muscle cell differentiation
0.47	GO:0045661	regulation of myoblast differentiation

0.46	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0005515	protein binding
0.34	GO:0004252	serine-type endopeptidase activity
0.32	GO:0003676	nucleic acid binding

0.55	GO:0031672	A band
0.54	GO:0031463	Cul3-RING ubiquitin ligase complex
0.48	GO:0031674	I band
0.47	GO:0033017	sarcoplasmic reticulum membrane
0.41	GO:0005856	cytoskeleton
0.41	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.38	GO:0005886	plasma membrane
0.36	GO:0034464	BBSome
0.34	GO:0031143	pseudopodium

0.34	EC:3.4.21	GO:0004252
0.46	KEGG:R03876	GO:0004842

sp|Q2TBC4|PRIC4_HUMAN
Prickle-like protein 4
Search

PRICKLE4

0.97	Prickle planar cell polarity protein 4

0.43	GO:0021535	cell migration in hindbrain
0.41	GO:0001764	neuron migration
0.41	GO:0060027	convergent extension involved in gastrulation
0.40	GO:0035622	intrahepatic bile duct development
0.40	GO:0071910	determination of liver left/right asymmetry
0.40	GO:0071907	determination of digestive tract left/right asymmetry
0.40	GO:0070121	Kupffer's vesicle development
0.39	GO:0042074	cell migration involved in gastrulation
0.39	GO:0003407	neural retina development
0.39	GO:0001947	heart looping

0.62	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003676	nucleic acid binding

0.39	GO:0005813	centrosome
0.37	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.33	GO:0005886	plasma membrane

sp|Q2TBE0|C19L2_HUMAN
CWF19-like protein 2
Search

CWF19L2

0.97	CWF19 like 2, cell cycle control (S. pombe)

0.48

GO:0006468

protein phosphorylation

0.48	GO:0004672	protein kinase activity
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

sp|Q2TBF2|WSCD2_HUMAN
WSC domain-containing protein 2
Search

WSCD2

0.96	WSC domain-containing protein 2

0.72

GO:0008146

sulfotransferase activity

0.30

GO:0044425

membrane part

0.72

EC:2.8.2

GO:0008146

sp|Q2TV78|MST1L_HUMAN
Putative macrophage stimulating 1-like protein
Search

MST1

0.89	Macrophage stimulating 1

0.74	GO:0060763	mammary duct terminal end bud growth
0.74	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.72	GO:0010758	regulation of macrophage chemotaxis
0.71	GO:1904036	negative regulation of epithelial cell apoptotic process
0.71	GO:0007566	embryo implantation
0.68	GO:0046425	regulation of JAK-STAT cascade
0.61	GO:0006508	proteolysis
0.60	GO:0010628	positive regulation of gene expression
0.46	GO:0030282	bone mineralization
0.44	GO:0006954	inflammatory response

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0030971	receptor tyrosine kinase binding

0.62	GO:0005773	vacuole
0.52	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle

0.69

GO:0004252

sp|Q2UY09|COSA1_HUMAN
Collagen alpha-1(XXVIII) chain
Search

0.92	Collagen type XXVIII alpha 1 chain

0.64	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0007155	cell adhesion

0.66

GO:0004867

serine-type endopeptidase inhibitor activity

0.68	GO:0005581	collagen trimer
0.49	GO:0005604	basement membrane
0.34	GO:0005788	endoplasmic reticulum lumen

sp|Q2V2M9|FHOD3_HUMAN
FH1/FH2 domain-containing protein 3
Search

FHOD3

0.80	Formin homology 2 domain containing 3

0.75	GO:0007015	actin filament organization
0.63	GO:0055003	cardiac myofibril assembly
0.61	GO:0045214	sarcomere organization
0.58	GO:0030837	negative regulation of actin filament polymerization

0.58

GO:0030017

sarcomere

sp|Q2VIQ3|KIF4B_HUMAN
Chromosome-associated kinesin KIF4B
Search

KIF4A

0.96	Kinesin family member 4

0.74	GO:0007018	microtubule-based movement
0.49	GO:0051256	mitotic spindle midzone assembly
0.46	GO:0000281	mitotic cytokinesis
0.38	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.37	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.35	GO:0030705	cytoskeleton-dependent intracellular transport
0.34	GO:0006629	lipid metabolic process
0.33	GO:0022008	neurogenesis
0.33	GO:0030030	cell projection organization

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042623	ATPase activity, coupled
0.35	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.35	GO:0003677	DNA binding

0.48	GO:0005871	kinesin complex
0.46	GO:0045171	intercellular bridge
0.44	GO:0030496	midbody
0.42	GO:0005874	microtubule
0.42	GO:0005654	nucleoplasm
0.38	GO:0016363	nuclear matrix
0.37	GO:0005694	chromosome
0.36	GO:0005829	cytosol
0.36	GO:1904115	axon cytoplasm
0.35	GO:0005819	spindle

0.35

EC:3.1.4.46

GO:0008889

sp|Q2VIR3|IF2GL_HUMAN
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
Search

EIF2S3

0.78	Eukaryotic translation initiation factor 2 subunit gamma X

0.62	GO:0006413	translational initiation
0.32	GO:0055085	transmembrane transport

0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.63	GO:0003743	translation initiation factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0045296	cadherin binding

0.44	GO:0005850	eukaryotic translation initiation factor 2 complex
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q2VPA4|CR1L_HUMAN
Complement component receptor 1-like protein
Search

0.76	Complement receptor type 2

0.64	GO:0042100	B cell proliferation
0.63	GO:0030183	B cell differentiation
0.48	GO:0045916	negative regulation of complement activation
0.48	GO:0002430	complement receptor mediated signaling pathway
0.38	GO:0006958	complement activation, classical pathway
0.37	GO:0045087	innate immune response

0.69	GO:0001848	complement binding
0.57	GO:0042803	protein homodimerization activity
0.48	GO:0004875	complement receptor activity
0.45	GO:0003677	DNA binding

0.64	GO:0043235	receptor complex
0.47	GO:0005576	extracellular region
0.45	GO:0009897	external side of plasma membrane
0.41	GO:0031982	vesicle
0.37	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q2VPB7|AP5B1_HUMAN
AP-5 complex subunit beta-1
Search

AP5B1

0.97	AP-5 complex subunit beta-1

0.78	GO:0016197	endosomal transport
0.47	GO:0015031	protein transport

0.39

GO:0005515

protein binding

0.78	GO:0030119	AP-type membrane coat adaptor complex
0.48	GO:0005765	lysosomal membrane

sp|Q2VPJ9|LR75B_HUMAN
Leucine-rich repeat-containing protein 75B
Search

LRRC75B

0.54	Leucine-rich repeat-containing protein 75B

0.53

GO:0003682

chromatin binding

0.30

GO:0044425

membrane part

sp|Q2VPK5|CTU2_HUMAN
Cytoplasmic tRNA 2-thiolation protein 2
Search

CTU2

0.77	Cytoplasmic tRNA 2-thiolation protein 2-B

0.79	GO:0032447	protein urmylation
0.77	GO:0034227	tRNA thio-modification
0.76	GO:0002098	tRNA wobble uridine modification

0.68	GO:0000049	tRNA binding
0.60	GO:0016779	nucleotidyltransferase activity
0.47	GO:0016783	sulfurtransferase activity
0.35	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.36	GO:0043234	protein complex

0.60

EC:2.7.7

GO:0016779

sp|Q2VWA4|SKOR2_HUMAN
SKI family transcriptional corepressor 2
Search

SKOR2

0.75	SKI family transcriptional corepressor 2

0.84	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.72	GO:1903507	negative regulation of nucleic acid-templated transcription
0.70	GO:0030514	negative regulation of BMP signaling pathway
0.62	GO:0030182	neuron differentiation
0.61	GO:0045595	regulation of cell differentiation
0.61	GO:0021936	regulation of cerebellar granule cell precursor proliferation
0.60	GO:0048468	cell development
0.60	GO:0021694	cerebellar Purkinje cell layer formation
0.60	GO:0021533	cell differentiation in hindbrain
0.59	GO:0045880	positive regulation of smoothened signaling pathway

0.85	GO:0046332	SMAD binding
0.81	GO:0003714	transcription corepressor activity
0.58	GO:0042826	histone deacetylase binding
0.54	GO:0003682	chromatin binding
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.37	GO:0005667	transcription factor complex

sp|Q2VWP7|PRTG_HUMAN
Protogenin
Search

PRTG

0.97	Protogenin homolog b (Gallus gallus)

0.69

GO:0007275

multicellular organism development

0.36	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|Q2VY69|ZN284_HUMAN
Zinc finger protein 284
Search

0.67	Zinc finger protein 221

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.39	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.37	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.41	GO:0017053	transcriptional repressor complex
0.40	GO:0043227	membrane-bounded organelle
0.38	GO:0012505	endomembrane system
0.37	GO:0044422	organelle part
0.37	GO:0031975	envelope
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|Q2VYF4|LETM2_HUMAN
LETM1 domain-containing protein LETM2, mitochondrial
Search

LETM2

0.95	Leucine zipper and EF-hand containing transmembrane protein 2

0.48

GO:0006875

cellular metal ion homeostasis

0.74	GO:0043022	ribosome binding
0.41	GO:0005509	calcium ion binding

0.61	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

sp|Q2WEN9|CEA16_HUMAN
Carcinoembryonic antigen-related cell adhesion molecule 16
Search

CEACAM16

0.86	Carcinoembryonic antigen related cell adhesion molecule 16

0.65	GO:0007605	sensory perception of sound
0.55	GO:0035385	Roundabout signaling pathway
0.53	GO:0001822	kidney development
0.52	GO:0007411	axon guidance
0.40	GO:0050925	negative regulation of negative chemotaxis
0.40	GO:0061364	apoptotic process involved in luteolysis
0.39	GO:0050772	positive regulation of axonogenesis
0.38	GO:0009888	tissue development
0.38	GO:0007420	brain development
0.38	GO:0035295	tube development

0.61	GO:0042802	identical protein binding
0.40	GO:0005509	calcium ion binding

0.71	GO:0032426	stereocilium tip
0.60	GO:0005615	extracellular space
0.55	GO:0030673	axolemma
0.38	GO:0009986	cell surface
0.36	GO:0005604	basement membrane
0.35	GO:0005938	cell cortex
0.35	GO:0030054	cell junction
0.34	GO:1903561	extracellular vesicle
0.34	GO:0032155	cell division site part
0.30	GO:0031224	intrinsic component of membrane

sp|Q2WGJ6|KLH38_HUMAN
Kelch-like protein 38
Search

KLHL38

0.97	Kelch like family member 38

0.73

GO:0016567

protein ubiquitination

0.74	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0005515	protein binding

0.83

GO:0031463

Cul3-RING ubiquitin ligase complex

0.74

GO:0004842

sp|Q2WGJ8|TM249_HUMAN
Transmembrane protein 249
Search

TMEM249

0.72	Transmembrane domain-containing protein (Fragment)

0.30

GO:0044425

membrane part

sp|Q2WGJ9|FR1L6_HUMAN
Fer-1-like protein 6
Search

FER1L6

0.94	Fer-1 like family member 6

0.30

GO:0044425

membrane part

sp|Q2WGN9|GAB4_HUMAN
GRB2-associated-binding protein 4
Search

GAB4

0.88	GRB2 associated binding protein family member 4

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0090668	endothelial cell chemotaxis to vascular endothelial growth factor
0.71	GO:0048731	system development
0.68	GO:0048518	positive regulation of biological process
0.67	GO:0045765	regulation of angiogenesis
0.63	GO:0031532	actin cytoskeleton reorganization
0.63	GO:0042127	regulation of cell proliferation
0.62	GO:0048646	anatomical structure formation involved in morphogenesis
0.60	GO:0030154	cell differentiation
0.60	GO:0002376	immune system process

0.74

GO:0005068

transmembrane receptor protein tyrosine kinase adaptor activity

0.48	GO:0005886	plasma membrane
0.43	GO:0005737	cytoplasm

tr|Q2XQG4|Q2XQG4_HUMAN
Kallikrein 9 (Fragment)
Search

0.68	Kallikrein-11

0.61	GO:0006508	proteolysis
0.40	GO:0009611	response to wounding
0.40	GO:0031642	negative regulation of myelination
0.39	GO:0043616	keratinocyte proliferation
0.39	GO:0048681	negative regulation of axon regeneration
0.39	GO:0007613	memory
0.38	GO:0050807	regulation of synapse organization
0.38	GO:0050808	synapse organization
0.38	GO:0048812	neuron projection morphogenesis
0.37	GO:0008219	cell death

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005509	calcium ion binding

0.43	GO:0005576	extracellular region
0.40	GO:0097180	serine protease inhibitor complex
0.38	GO:0030141	secretory granule
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|Q2Y0W8|S4A8_HUMAN
Electroneutral sodium bicarbonate exchanger 1
Search

SLC4A8

0.64	Anion exchange protein (Fragment)

0.69	GO:0098656	anion transmembrane transport
0.69	GO:0015698	inorganic anion transport
0.47	GO:0030641	regulation of cellular pH
0.46	GO:0015701	bicarbonate transport
0.43	GO:0035725	sodium ion transmembrane transport
0.40	GO:0021860	pyramidal neuron development
0.39	GO:0035641	locomotory exploration behavior
0.39	GO:0048854	brain morphogenesis
0.39	GO:0035264	multicellular organism growth
0.38	GO:0009791	post-embryonic development

0.83	GO:0005452	inorganic anion exchanger activity
0.48	GO:0008510	sodium:bicarbonate symporter activity
0.38	GO:0015301	anion:anion antiporter activity

0.56	GO:0032809	neuronal cell body membrane
0.52	GO:0043005	neuron projection
0.41	GO:0005887	integral component of plasma membrane
0.38	GO:0016323	basolateral plasma membrane
0.37	GO:0120038	plasma membrane bounded cell projection part

sp|Q2YD98|UVSSA_HUMAN
UV-stimulated scaffold protein A
Search

sp|Q30154|DRB5_HUMAN
HLA class II histocompatibility antigen, DR beta 5 chain
Search

0.52	HLA class II histocompatibility antigen, DR beta 5 chain

0.82	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.64	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.64	GO:0031295	T cell costimulation
0.63	GO:0050852	T cell receptor signaling pathway
0.58	GO:0019221	cytokine-mediated signaling pathway
0.54	GO:0006952	defense response
0.48	GO:2001179	regulation of interleukin-10 secretion
0.47	GO:0032673	regulation of interleukin-4 production
0.47	GO:0032689	negative regulation of interferon-gamma production

0.57	GO:0032395	MHC class II receptor activity
0.55	GO:0042605	peptide antigen binding

0.75	GO:0042613	MHC class II protein complex
0.67	GO:0031902	late endosome membrane
0.66	GO:0005765	lysosomal membrane
0.64	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.62	GO:0032588	trans-Golgi network membrane
0.62	GO:0030669	clathrin-coated endocytic vesicle membrane
0.59	GO:0012507	ER to Golgi transport vesicle membrane
0.51	GO:0070062	extracellular exosome
0.45	GO:0009897	external side of plasma membrane
0.41	GO:0005887	integral component of plasma membrane

sp|Q30201|HFE_HUMAN
Hereditary hemochromatosis protein
Search

HFE

0.97	Hereditary hemochromatosis protein homolog

0.87	GO:0002626	negative regulation of T cell antigen processing and presentation
0.86	GO:0098711	iron ion import across plasma membrane
0.75	GO:0006879	cellular iron ion homeostasis
0.61	GO:1904283	negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
0.61	GO:2001186	negative regulation of CD8-positive, alpha-beta T cell activation
0.60	GO:1904440	positive regulation of ferrous iron import across plasma membrane
0.60	GO:1904435	regulation of transferrin receptor binding
0.60	GO:1904434	positive regulation of ferrous iron binding
0.59	GO:0002725	negative regulation of T cell cytokine production
0.59	GO:1900122	positive regulation of receptor binding

0.86	GO:1990459	transferrin receptor binding
0.59	GO:0030881	beta-2-microglobulin binding
0.59	GO:0039706	co-receptor binding
0.40	GO:0042605	peptide antigen binding

0.86	GO:1990712	HFE-transferrin receptor complex
0.56	GO:0045178	basal part of cell
0.55	GO:0055037	recycling endosome
0.54	GO:0009897	external side of plasma membrane
0.54	GO:0045177	apical part of cell
0.54	GO:0005769	early endosome
0.53	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005615	extracellular space
0.42	GO:1990357	terminal web
0.39	GO:0042612	MHC class I protein complex

sp|Q309B1|TR16L_HUMAN
Tripartite motif-containing protein 16-like protein
Search

TRIM16

0.88	Tripartite motif-containing protein 16

0.45	GO:0048386	positive regulation of retinoic acid receptor signaling pathway
0.44	GO:0045618	positive regulation of keratinocyte differentiation
0.44	GO:0050718	positive regulation of interleukin-1 beta secretion
0.43	GO:0060416	response to growth hormone
0.43	GO:0043966	histone H3 acetylation
0.42	GO:0043967	histone H4 acetylation
0.41	GO:0032526	response to retinoic acid
0.41	GO:0046683	response to organophosphorus
0.40	GO:0045893	positive regulation of transcription, DNA-templated

0.62	GO:0008270	zinc ion binding
0.46	GO:0032089	NACHT domain binding
0.44	GO:0019966	interleukin-1 binding
0.36	GO:0003677	DNA binding
0.34	GO:0016874	ligase activity
0.34	GO:0051087	chaperone binding

0.45	GO:0005622	intracellular
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0005886	plasma membrane
0.36	GO:0044422	organelle part
0.36	GO:0043227	membrane-bounded organelle

0.34

GO:0016874

sp|Q30KP8|DB136_HUMAN
Beta-defensin 136
Search

DEFB136

0.97	Beta-defensin 136

0.78

GO:0042742

defense response to bacterium

0.44

GO:0005576

extracellular region

sp|Q30KP9|DB135_HUMAN
Beta-defensin 135
Search

DEFB135

0.59	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.55	GO:0009986	cell surface

sp|Q30KQ1|DB133_HUMAN
Beta-defensin 133
Search

DEFB133

0.57	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.52	GO:0009986	cell surface

sp|Q30KQ2|DB130_HUMAN
Beta-defensin 130
Search

0.71	GO:0006952	defense response
0.50	GO:0009617	response to bacterium
0.45	GO:0001562	response to protozoan
0.45	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.45	GO:0051801	cytolysis in other organism involved in symbiotic interaction
0.44	GO:0051851	modification by host of symbiont morphology or physiology

0.66	GO:0005576	extracellular region
0.42	GO:0044164	host cell cytosol

sp|Q30KQ4|DB116_HUMAN
Beta-defensin 116
Search

DEFB116

0.60	Beta-defensin

0.79	GO:0045087	innate immune response
0.76	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.57	GO:0009986	cell surface
0.30	GO:0044425	membrane part

sp|Q30KQ5|DB115_HUMAN
Beta-defensin 115
Search

DEFB115

0.57	Beta-defensin

0.79	GO:0045087	innate immune response
0.63	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.57	GO:0009986	cell surface

sp|Q30KQ6|DB114_HUMAN
Beta-defensin 114
Search

DEFB114

0.55	Beta-defensin

0.86	GO:0061760	antifungal innate immune response
0.85	GO:1904468	negative regulation of tumor necrosis factor secretion
0.85	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.80	GO:0050830	defense response to Gram-positive bacterium
0.79	GO:0043407	negative regulation of MAP kinase activity
0.79	GO:0050729	positive regulation of inflammatory response
0.79	GO:0050829	defense response to Gram-negative bacterium

0.78

GO:0001530

lipopolysaccharide binding

0.65	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q30KQ7|DB113_HUMAN
Beta-defensin 113
Search

DEFB113

0.61	Beta-defensin

0.78	GO:0045087	innate immune response
0.77	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q30KQ8|DB112_HUMAN
Beta-defensin 112
Search

DEFB112

0.58	Beta-defensin

0.79	GO:0045087	innate immune response
0.76	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.52	GO:0009986	cell surface

sp|Q30KQ9|DB110_HUMAN
Beta-defensin 110
Search

DEFB110

0.63	Beta-defensin

0.79	GO:0045087	innate immune response
0.77	GO:0042742	defense response to bacterium
0.38	GO:0060046	regulation of acrosome reaction
0.38	GO:0007339	binding of sperm to zona pellucida
0.35	GO:0065009	regulation of molecular function

0.38

GO:0005246

calcium channel regulator activity

0.66	GO:0005576	extracellular region
0.54	GO:0009986	cell surface
0.30	GO:0044425	membrane part

sp|Q30KR1|DB109_HUMAN
Beta-defensin 109
Search

0.55	Beta-defensin

0.72	GO:0006952	defense response
0.60	GO:0009617	response to bacterium
0.52	GO:0006955	immune response

0.66

GO:0005576

extracellular region

sp|Q31612|1B73_HUMAN
HLA class I histocompatibility antigen, B-73 alpha chain
Search

0.40	Chimpanzee MHC class I ChlA chain

0.74	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.67	GO:0006955	immune response
0.39	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.38	GO:0019221	cytokine-mediated signaling pathway
0.37	GO:0006952	defense response
0.37	GO:0050776	regulation of immune response
0.35	GO:0016032	viral process
0.34	GO:2000568	positive regulation of memory T cell activation
0.34	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation
0.34	GO:0051290	protein heterotetramerization

0.39	GO:0042605	peptide antigen binding
0.36	GO:0030881	beta-2-microglobulin binding
0.35	GO:0005102	receptor binding
0.34	GO:0046977	TAP binding
0.33	GO:0032403	protein complex binding
0.33	GO:0003723	RNA binding

0.73	GO:0042612	MHC class I protein complex
0.39	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.39	GO:0030670	phagocytic vesicle membrane
0.39	GO:0055038	recycling endosome membrane
0.38	GO:0031901	early endosome membrane
0.38	GO:0012507	ER to Golgi transport vesicle membrane
0.37	GO:0009986	cell surface
0.37	GO:0000139	Golgi membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0070971	endoplasmic reticulum exit site

sp|Q32M45|ANO4_HUMAN
Anoctamin-4
Search

ANO4

0.67

Anoctamin

0.85	GO:0061588	calcium activated phospholipid scrambling
0.50	GO:0006821	chloride transport
0.48	GO:0098661	inorganic anion transmembrane transport
0.37	GO:0006869	lipid transport

0.67	GO:0046983	protein dimerization activity
0.56	GO:0017128	phospholipid scramblase activity
0.56	GO:0061778	intracellular chloride channel activity
0.49	GO:0022839	ion gated channel activity
0.48	GO:0008381	mechanosensitive ion channel activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q32M78|ZN699_HUMAN
Zinc finger protein 699
Search

0.69	Zinc finger protein 699

0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0010468	regulation of gene expression
0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle

sp|Q32M84|BTBDG_HUMAN
BTB/POZ domain-containing protein 16
Search

BTBD16

0.97	BTB/POZ domain-containing protein 16

0.76	GO:0000151	ubiquitin ligase complex
0.61	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q32M88|PGGHG_HUMAN
Protein-glucosylgalactosylhydroxylysine glucosidase
Search

PGGHG

0.97	Protein-glucosylgalactosylhydroxylysine glucosidase

0.59

GO:0005975

carbohydrate metabolic process

0.61	GO:0047402	protein-glucosylgalactosylhydroxylysine glucosidase activity
0.34	GO:0030246	carbohydrate binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005829	cytosol
0.45	GO:0005618	cell wall
0.30	GO:0031224	intrinsic component of membrane

0.61

EC:3.2.1.107

GO:0047402

sp|Q32M92|CO032_HUMAN
Uncharacterized protein C15orf32
Search

sp|Q32MH5|F214A_HUMAN
Protein FAM214A
Search

sp|Q32MK0|MYLK3_HUMAN
Myosin light chain kinase 3
Search

MYLK3

0.97	Myosin light chain kinase 3

0.66	GO:0002528	regulation of vascular permeability involved in acute inflammatory response
0.63	GO:0006468	protein phosphorylation
0.61	GO:0071347	cellular response to interleukin-1
0.61	GO:0045214	sarcomere organization
0.53	GO:0018210	peptidyl-threonine modification
0.53	GO:0048769	sarcomerogenesis
0.52	GO:0018209	peptidyl-serine modification
0.52	GO:0055003	cardiac myofibril assembly
0.44	GO:0035556	intracellular signal transduction
0.41	GO:0060298	positive regulation of sarcomere organization

0.68	GO:0004687	myosin light chain kinase activity
0.59	GO:0004683	calmodulin-dependent protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0015629	actin cytoskeleton
0.41	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome
0.35	GO:0030906	retromer, cargo-selective complex
0.30	GO:0016021	integral component of membrane

0.68

EC:2.7.11.18

GO:0004687

sp|Q32MQ0|ZN750_HUMAN
Zinc finger protein 750
Search

ZNF750

0.96	LOW QUALITY PROTEIN: zinc finger protein 750

0.82	GO:0008544	epidermis development
0.76	GO:0006366	transcription by RNA polymerase II
0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0030154	cell differentiation

0.85	GO:1990841	promoter-specific chromatin binding
0.84	GO:0001046	core promoter sequence-specific DNA binding
0.82	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|Q32MZ4|LRRF1_HUMAN
Leucine-rich repeat flightless-interacting protein 1
Search

LRRFIP1

0.93	Leucine-rich repeat flightless-interacting protein 1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process
0.48	GO:0031327	negative regulation of cellular biosynthetic process
0.41	GO:0032481	positive regulation of type I interferon production
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0044093	positive regulation of molecular function

0.53	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0045296	cadherin binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0042803	protein homodimerization activity
0.39	GO:0003725	double-stranded RNA binding

0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0005856	cytoskeleton
0.37	GO:0005634	nucleus

sp|Q32NB8|PGPS1_HUMAN
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
Search

PGS1

0.42	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

0.79	GO:0032049	cardiolipin biosynthetic process
0.40	GO:0046339	diacylglycerol metabolic process
0.34	GO:0007018	microtubule-based movement

0.79	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0016887	ATPase activity

0.51	GO:0005783	endoplasmic reticulum
0.47	GO:0005739	mitochondrion
0.35	GO:0019866	organelle inner membrane

0.79	EC:2.7.8.5	GO:0008444
0.79	KEGG:R01801	GO:0008444

sp|Q32NC0|CR021_HUMAN
UPF0711 protein C18orf21
Search

sp|Q32P28|P3H1_HUMAN
Prolyl 3-hydroxylase 1
Search

P3H1

0.97	LOW QUALITY PROTEIN: prolyl 3-hydroxylase 1

0.62	GO:0018126	protein hydroxylation
0.60	GO:1901874	negative regulation of post-translational protein modification
0.55	GO:0032963	collagen metabolic process
0.55	GO:0060348	bone development
0.53	GO:0050821	protein stabilization
0.53	GO:0050708	regulation of protein secretion
0.52	GO:0055114	oxidation-reduction process
0.49	GO:0018208	peptidyl-proline modification
0.48	GO:0006457	protein folding
0.46	GO:0008285	negative regulation of cell proliferation

0.77	GO:0031418	L-ascorbic acid binding
0.66	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.61	GO:0005506	iron ion binding
0.48	GO:0051213	dioxygenase activity
0.42	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0005518	collagen binding

0.53	GO:0005783	endoplasmic reticulum
0.48	GO:0005604	basement membrane
0.43	GO:0005794	Golgi apparatus
0.38	GO:0070062	extracellular exosome
0.37	GO:0016528	sarcoplasm
0.35	GO:0043233	organelle lumen
0.35	GO:0005634	nucleus
0.34	GO:0044446	intracellular organelle part
0.34	GO:0032991	macromolecular complex
0.33	GO:0005886	plasma membrane

0.66

GO:0016705

sp|Q32P41|TRM5_HUMAN
tRNA (guanine(37)-N1)-methyltransferase
Search

TRMT5

0.72	tRNA (Guanine-N(1)-)-methyltransferase (Fragment)

0.73	GO:0030488	tRNA methylation
0.58	GO:0070900	mitochondrial tRNA modification

0.78

GO:0009019

tRNA (guanine-N1-)-methyltransferase activity

0.74	GO:0005759	mitochondrial matrix
0.60	GO:0005634	nucleus

0.78

GO:0009019

sp|Q32P44|EMAL3_HUMAN
Echinoderm microtubule-associated protein-like 3
Search

EML3

0.97	Echinoderm microtubule associated protein like 3

0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression

0.57	GO:0008017	microtubule binding
0.46	GO:0003682	chromatin binding
0.41	GO:0043565	sequence-specific DNA binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.30	GO:0003824	catalytic activity

0.55	GO:0015630	microtubule cytoskeleton
0.42	GO:0090545	CHD-type complex
0.41	GO:0090568	nuclear transcriptional repressor complex
0.41	GO:0000118	histone deacetylase complex
0.41	GO:0099513	polymeric cytoskeletal fiber
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q32P51|RA1L2_HUMAN
Heterogeneous nuclear ribonucleoprotein A1-like 2
Search

HNRNPA1

0.85	Heterogeneous nuclear ribonucleoprotein A1

0.53	GO:1903936	cellular response to sodium arsenite
0.48	GO:0032211	negative regulation of telomere maintenance via telomerase
0.48	GO:0032212	positive regulation of telomere maintenance via telomerase
0.47	GO:0042149	cellular response to glucose starvation
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.44	GO:0051168	nuclear export
0.44	GO:0051170	nuclear import
0.43	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.49	GO:0098505	G-rich strand telomeric DNA binding
0.45	GO:0019904	protein domain specific binding
0.38	GO:0036310	annealing helicase activity
0.38	GO:0042802	identical protein binding
0.36	GO:0008134	transcription factor binding

0.65	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0044428	nuclear part
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:1902494	catalytic complex
0.39	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.33	GO:0048475	coated membrane
0.32	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q32Q52|CL074_HUMAN
Uncharacterized protein C12orf74
Search

sp|Q32ZL2|PLPR5_HUMAN
Phospholipid phosphatase-related protein type 5
Search

PLPPR5

0.96	Phospholipid phosphatase-related protein type 5

0.72	GO:0051491	positive regulation of filopodium assembly
0.69	GO:0010976	positive regulation of neuron projection development
0.56	GO:0046839	phospholipid dephosphorylation
0.49	GO:0006644	phospholipid metabolic process
0.46	GO:0007165	signal transduction

0.60	GO:0042577	lipid phosphatase activity
0.59	GO:0008195	phosphatidate phosphatase activity

0.50	GO:0005886	plasma membrane
0.39	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.59

EC:3.1.3.4

GO:0008195

sp|Q330K2|NDUF6_HUMAN
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
Search

NDUFAF6

0.96	NADH:ubiquinone oxidoreductase complex assembly factor 6

0.59	GO:0032981	mitochondrial respiratory chain complex I assembly
0.49	GO:0009058	biosynthetic process
0.33	GO:0050821	protein stabilization

0.51	GO:0016740	transferase activity
0.32	GO:0003723	RNA binding

0.46	GO:0005739	mitochondrion
0.46	GO:0019866	organelle inner membrane
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.51

GO:0016740

sp|Q33E94|RFX4_HUMAN
Transcription factor RFX4
Search

RFX4

0.92	Transcription factor RFX4

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
0.43	GO:0021516	dorsal spinal cord development
0.42	GO:0021696	cerebellar cortex morphogenesis
0.42	GO:0030901	midbrain development
0.42	GO:0021537	telencephalon development
0.41	GO:0006366	transcription by RNA polymerase II
0.41	GO:1902680	positive regulation of RNA biosynthetic process

0.55	GO:0003677	DNA binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.37

GO:0005634

nucleus

sp|Q38SD2|LRRK1_HUMAN
Leucine-rich repeat serine/threonine-protein kinase 1
Search

LRRK1

0.94	Leucine-rich repeat serine/threonine-protein kinase 1

0.63	GO:0036035	osteoclast development
0.62	GO:0006468	protein phosphorylation
0.61	GO:0045453	bone resorption
0.60	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.60	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.58	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.55	GO:1902533	positive regulation of intracellular signal transduction
0.41	GO:0035556	intracellular signal transduction

0.63	GO:0004672	protein kinase activity
0.54	GO:0042802	identical protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004871	signal transducer activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0046872	metal ion binding

0.51	GO:0005829	cytosol
0.47	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|Q3B726|RPA43_HUMAN
DNA-directed RNA polymerase I subunit RPA43
Search

TWISTNB

0.93	TWIST neighbor

0.58	GO:0006351	transcription, DNA-templated
0.54	GO:1990823	response to leukemia inhibitory factor
0.51	GO:0071345	cellular response to cytokine stimulus

0.70

GO:0003899

DNA-directed 5'-3' RNA polymerase activity

0.57

GO:0005736

DNA-directed RNA polymerase I complex

0.70

EC:2.7.7.6

GO:0003899

sp|Q3B7I2|CNPY1_HUMAN
Protein canopy homolog 1
Search

CNPY1

0.97	Canopy FGF signaling regulator 1

0.71	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process
0.69	GO:0010988	regulation of low-density lipoprotein particle clearance
0.67	GO:0007167	enzyme linked receptor protein signaling pathway
0.66	GO:0009888	tissue development
0.54	GO:0010629	negative regulation of gene expression
0.46	GO:0070121	Kupffer's vesicle development
0.46	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.45	GO:0007368	determination of left/right symmetry
0.44	GO:0044344	cellular response to fibroblast growth factor stimulus
0.44	GO:0009952	anterior/posterior pattern specification

0.42	GO:0004108	citrate (Si)-synthase activity
0.39	GO:0004535	poly(A)-specific ribonuclease activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.62	GO:0005783	endoplasmic reticulum
0.39	GO:0031251	PAN complex
0.39	GO:0000932	P-body
0.35	GO:0005759	mitochondrial matrix
0.35	GO:0005634	nucleus
0.35	GO:0005887	integral component of plasma membrane

0.42

EC:2.3.3.1

GO:0004108

sp|Q3B7J2|GFOD2_HUMAN
Glucose-fructose oxidoreductase domain-containing protein 2
Search

GFOD2

0.44	Glucose-fructose oxidoreductase domain-containing protein 2

0.53	GO:0030198	extracellular matrix organization
0.52	GO:0055114	oxidation-reduction process
0.36	GO:0042843	D-xylose catabolic process

0.53	GO:0016491	oxidoreductase activity
0.33	GO:0005515	protein binding

0.52	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0044425	membrane part

0.53

GO:0016491

sp|Q3B7S5|SMI21_HUMAN
Small integral membrane protein 21
Search

SMIM21

0.97	Small integral membrane protein 21

0.30

GO:0044425

membrane part

sp|Q3B7T1|EDRF1_HUMAN
Erythroid differentiation-related factor 1
Search

EDRF1

0.96	Erythroid differentiation regulatory factor 1

0.72	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0097659	nucleic acid-templated transcription
0.37	GO:0010467	gene expression
0.37	GO:0034645	cellular macromolecule biosynthetic process

0.36

GO:0005515

protein binding

0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q3B7T3|BEAN1_HUMAN
Protein BEAN1
Search

BEAN1

0.97	Brain expressed associated with NEDD4 1

0.33	GO:0016575	histone deacetylation
0.33	GO:0042545	cell wall modification
0.32	GO:0045490	pectin catabolic process
0.32	GO:0016042	lipid catabolic process
0.32	GO:0035556	intracellular signal transduction
0.32	GO:0055085	transmembrane transport

0.35	GO:0005515	protein binding
0.33	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0045330	aspartyl esterase activity
0.33	GO:0030599	pectinesterase activity
0.32	GO:0031177	phosphopantetheine binding
0.32	GO:0004871	signal transducer activity
0.32	GO:0008270	zinc ion binding

0.32	GO:0005618	cell wall
0.32	GO:0005576	extracellular region
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33	EC:3.1.4.11	GO:0004435
0.33	KEGG:R03435	GO:0004435

sp|Q3B820|F161A_HUMAN
Protein FAM161A
Search

sp|Q3B8N2|LEG9B_HUMAN
Galectin-9B
Search

LGALS9

0.59

Galectin

0.43	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation
0.43	GO:2001181	positive regulation of interleukin-10 secretion
0.43	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.43	GO:0043301	negative regulation of leukocyte degranulation
0.43	GO:0070241	positive regulation of activated T cell autonomous cell death
0.43	GO:0045591	positive regulation of regulatory T cell differentiation
0.43	GO:1902713	regulation of interferon-gamma secretion
0.43	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.43	GO:2000778	positive regulation of interleukin-6 secretion
0.42	GO:0032689	negative regulation of interferon-gamma production

0.70	GO:0030246	carbohydrate binding
0.42	GO:0016936	galactoside binding
0.39	GO:0005515	protein binding
0.38	GO:0043539	protein serine/threonine kinase activator activity
0.36	GO:0004871	signal transducer activity
0.34	GO:0036094	small molecule binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.42	GO:0005829	cytosol
0.40	GO:0005576	extracellular region
0.38	GO:0005634	nucleus
0.37	GO:0031982	vesicle

0.38

EC:1.97.1

GO:0051353

sp|Q3B8N5|PROX2_HUMAN
Prospero homeobox protein 2
Search

PROX2

0.97	Prospero homeobox protein 2

0.60	GO:0060836	lymphatic endothelial cell differentiation
0.60	GO:0070309	lens fiber cell morphogenesis
0.59	GO:0001946	lymphangiogenesis
0.57	GO:0055007	cardiac muscle cell differentiation
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0030182	neuron differentiation
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:2000979	positive regulation of forebrain neuron differentiation
0.47	GO:0090425	acinar cell differentiation
0.47	GO:0002194	hepatocyte cell migration

0.55	GO:0003677	DNA binding
0.53	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0050692	DBD domain binding
0.47	GO:0050693	LBD domain binding
0.46	GO:0016922	ligand-dependent nuclear receptor binding
0.44	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.44	GO:0003714	transcription corepressor activity
0.42	GO:0001067	regulatory region nucleic acid binding

0.48	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q3BBV0|NBPF1_HUMAN
Neuroblastoma breakpoint family member 1
Search

0.10	Neuroblastoma breakpoint family member 1

0.42	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q3BBV1|NBPFK_HUMAN
Neuroblastoma breakpoint family member 20
Search

0.10	Neuroblastoma breakpoint family member 20

0.45	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q3BBV2|NBPF8_HUMAN
Putative neuroblastoma breakpoint family member 8
Search

0.82	Neuroblastoma breakpoint family member 9

0.49

GO:0005737

cytoplasm

sp|Q3BBW0|NBPF9_HUMAN
Neuroblastoma breakpoint family member 9
Search

0.10	Neuroblastoma breakpoint family member 9

0.37

GO:0003723

RNA binding

0.47	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q3C1V0|M4A18_HUMAN
Membrane-spanning 4-domains subfamily A member 18
Search

MS4A18

0.96	Membrane-spanning 4-domains subfamily A member 18

0.33

GO:0005887

integral component of plasma membrane

sp|Q3C1V1|CK091_HUMAN
Uncharacterized protein C11orf91
Search

sp|Q3C1V8|BSH_HUMAN
Brain-specific homeobox protein homolog
Search

BSX

0.96	Hematopoietically-expressed homeobox protein hhex

0.62	GO:0060056	mammary gland involution
0.62	GO:0042755	eating behavior
0.58	GO:0007626	locomotory behavior
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0007420	brain development
0.40	GO:0048663	neuron fate commitment
0.37	GO:0006366	transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.47	GO:0003700	DNA binding transcription factor activity
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0030545	receptor regulator activity

0.61	GO:0005634	nucleus
0.54	GO:0005667	transcription factor complex
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q3C1V9|YK041_HUMAN
Putative uncharacterized protein ENSP00000334305
Search

sp|Q3I5F7|ACOT6_HUMAN
Putative acyl-coenzyme A thioesterase 6
Search

ACOT6

0.88	Acyl-coenzyme A thioesterase 2, mitochondrial

0.71	GO:0035383	thioester metabolic process
0.61	GO:0006732	coenzyme metabolic process
0.60	GO:0032789	unsaturated monocarboxylic acid metabolic process
0.60	GO:0032788	saturated monocarboxylic acid metabolic process
0.57	GO:0000038	very long-chain fatty acid metabolic process
0.55	GO:0001676	long-chain fatty acid metabolic process
0.53	GO:0006793	phosphorus metabolic process
0.50	GO:0043649	dicarboxylic acid catabolic process
0.50	GO:0046459	short-chain fatty acid metabolic process
0.36	GO:0070849	response to epidermal growth factor

0.74	GO:0016790	thiolester hydrolase activity
0.49	GO:0005102	receptor binding
0.45	GO:0052689	carboxylic ester hydrolase activity

0.53	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.40	GO:0031907	microbody lumen
0.39	GO:0005759	mitochondrial matrix
0.38	GO:0070062	extracellular exosome

0.74	EC:3.1.2	GO:0016790
0.45	KEGG:R00630	GO:0052689

sp|Q3KNS1|PTHD3_HUMAN
Patched domain-containing protein 3
Search

PTCHD3

0.74	Patched domain-containing protein 3

0.38	GO:0007286	spermatid development
0.32	GO:0055085	transmembrane transport
0.32	GO:0007165	signal transduction
0.31	GO:0006508	proteolysis

0.33	GO:0008158	hedgehog receptor activity
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0003676	nucleic acid binding
0.31	GO:0004252	serine-type endopeptidase activity

0.44	GO:0097225	sperm midpiece
0.30	GO:0016020	membrane

0.31

GO:0004252

sp|Q3KNS6|ZN829_HUMAN
Zinc finger protein 829
Search

0.42	Zinc finger protein 829

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.36	GO:0097659	nucleic acid-templated transcription
0.35	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0003700	DNA binding transcription factor activity

0.48	GO:0031965	nuclear membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q3KNT7|NSN5B_HUMAN
Putative NOL1/NOP2/Sun domain family member 5B
Search

NSUN5

0.60	NOP2/Sun RNA methyltransferase family member 5

0.63	GO:0032259	methylation
0.47	GO:0000154	rRNA modification
0.38	GO:0044260	cellular macromolecule metabolic process
0.37	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.32	GO:0006400	tRNA modification

0.63	GO:0008168	methyltransferase activity
0.59	GO:0003723	RNA binding
0.43	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0008270	zinc ion binding
0.33	GO:0016874	ligase activity

0.53	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.63

GO:0008168

sp|Q3KNT9|TMM95_HUMAN
Transmembrane protein 95
Search

TMEM95

0.97	Transmembrane protein 95

0.30

GO:0044425

membrane part

sp|Q3KNV8|PCGF3_HUMAN
Polycomb group RING finger protein 3
Search

PCGF3

0.95	Polycomb group RING finger protein 3

0.86	GO:0060819	inactivation of X chromosome by genetic imprinting
0.86	GO:0036353	histone H2A-K119 monoubiquitination
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.41	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity
0.39	GO:0003924	GTPase activity
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.38	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.84	GO:0000805	X chromosome
0.81	GO:0031519	PcG protein complex
0.68	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:2.3.1.97

GO:0004379

sp|Q3KNW1|SNAI3_HUMAN
Zinc finger protein SNAI3
Search

SNAI3

0.89	Zinc-finger transcription factor

0.59	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0035921	desmosome disassembly
0.56	GO:0070563	negative regulation of vitamin D receptor signaling pathway
0.55	GO:0010957	negative regulation of vitamin D biosynthetic process
0.55	GO:2000810	regulation of bicellular tight junction assembly
0.54	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.54	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.54	GO:0035414	negative regulation of catenin import into nucleus
0.54	GO:0010839	negative regulation of keratinocyte proliferation
0.54	GO:2000811	negative regulation of anoikis

0.62	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.61	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0005507	copper ion binding
0.44	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0003682	chromatin binding
0.35	GO:0005515	protein binding

0.50	GO:0005667	transcription factor complex
0.49	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.45	GO:0070013	intracellular organelle lumen
0.35	GO:0005737	cytoplasm
0.35	GO:0000775	chromosome, centromeric region

sp|Q3KNW5|SOAT_HUMAN
Solute carrier family 10 member 6
Search

0.96	Solute carrier family 10 (Sodium/bile acid cotransporter family), member 2

0.81	GO:0043251	sodium-dependent organic anion transport
0.67	GO:0015721	bile acid and bile salt transport
0.41	GO:0006814	sodium ion transport
0.36	GO:0055085	transmembrane transport

0.81	GO:0043250	sodium-dependent organic anion transmembrane transporter activity
0.69	GO:0008508	bile acid:sodium symporter activity

0.62	GO:0016324	apical plasma membrane
0.51	GO:0005902	microvillus
0.30	GO:0016021	integral component of membrane

sp|Q3KP22|MAJIN_HUMAN
Membrane-anchored junction protein
Search

MAJIN

0.75	Membrane-anchored junction protein

0.70	GO:0070197	meiotic attachment of telomere to nuclear envelope
0.67	GO:0007129	synapsis

0.55

GO:0003677

DNA binding

0.67	GO:0031229	intrinsic component of nuclear inner membrane
0.65	GO:0000784	nuclear chromosome, telomeric region
0.62	GO:0031301	integral component of organelle membrane

sp|Q3KP31|ZN791_HUMAN
Zinc finger protein 791
Search

0.67	Zinc finger protein 791

0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression
0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process
0.33	GO:0006974	cellular response to DNA damage stimulus

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding
0.36	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle

sp|Q3KP44|ANR55_HUMAN
Ankyrin repeat domain-containing protein 55
Search

ANKRD55

0.97	LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 55

0.77	GO:0003323	type B pancreatic cell development
0.70	GO:0042593	glucose homeostasis
0.39	GO:0030001	metal ion transport
0.36	GO:0016567	protein ubiquitination
0.36	GO:0055085	transmembrane transport
0.35	GO:0035556	intracellular signal transduction
0.35	GO:0016310	phosphorylation

0.39	GO:0046873	metal ion transmembrane transporter activity
0.35	GO:0016301	kinase activity

0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q3KP66|CA106_HUMAN
Uncharacterized protein C1orf106
Search

INAVA

0.97	Innate immunity activator

0.75	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
0.74	GO:0032494	response to peptidoglycan
0.73	GO:0032495	response to muramyl dipeptide
0.73	GO:0002367	cytokine production involved in immune response
0.73	GO:0032731	positive regulation of interleukin-1 beta production
0.73	GO:0032733	positive regulation of interleukin-10 production
0.70	GO:0032755	positive regulation of interleukin-6 production
0.69	GO:0000187	activation of MAPK activity
0.69	GO:0032874	positive regulation of stress-activated MAPK cascade
0.69	GO:1903409	reactive oxygen species biosynthetic process

0.46	GO:0030674	protein binding, bridging
0.32	GO:0008092	cytoskeletal protein binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding
0.32	GO:0004222	metalloendopeptidase activity
0.31	GO:0046872	metal ion binding

0.53	GO:0005856	cytoskeleton
0.53	GO:0005634	nucleus
0.46	GO:0005923	bicellular tight junction
0.44	GO:0005737	cytoplasm
0.35	GO:0005912	adherens junction
0.33	GO:0001726	ruffle
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.32

GO:0004222

sp|Q3KPI0|CEA21_HUMAN
Carcinoembryonic antigen-related cell adhesion molecule 21
Search

0.89	Pregnancy-specific beta-1-glycoprotein 1

0.47	GO:0043317	regulation of cytotoxic T cell degranulation
0.46	GO:0016477	cell migration
0.46	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.45	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.45	GO:0043301	negative regulation of leukocyte degranulation
0.45	GO:0030334	regulation of cell migration
0.44	GO:0050860	negative regulation of T cell receptor signaling pathway
0.44	GO:0007565	female pregnancy
0.44	GO:0090505	epiboly involved in wound healing
0.43	GO:0050868	negative regulation of T cell activation

0.44	GO:0031005	filamin binding
0.43	GO:1990782	protein tyrosine kinase binding
0.43	GO:0019903	protein phosphatase binding
0.42	GO:0042803	protein homodimerization activity
0.41	GO:0003779	actin binding
0.40	GO:0015125	bile acid transmembrane transporter activity
0.38	GO:0005516	calmodulin binding
0.38	GO:0034235	GPI anchor binding
0.37	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.37	GO:0046790	virion binding

0.48	GO:0005615	extracellular space
0.44	GO:0042101	T cell receptor complex
0.43	GO:0009986	cell surface
0.42	GO:0031225	anchored component of membrane
0.42	GO:1903561	extracellular vesicle
0.42	GO:0030667	secretory granule membrane
0.41	GO:0005911	cell-cell junction
0.41	GO:0016323	basolateral plasma membrane
0.41	GO:0070820	tertiary granule
0.40	GO:0042582	azurophil granule

sp|Q3KQU3|MA7D1_HUMAN
MAP7 domain-containing protein 1
Search

MAP7D1

0.94	MAP7 domain-containing protein 1

0.75	GO:0000226	microtubule cytoskeleton organization
0.32	GO:0005975	carbohydrate metabolic process

0.42	GO:0005198	structural molecule activity
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.70	GO:0015630	microtubule cytoskeleton
0.50	GO:0005829	cytosol
0.37	GO:0044430	cytoskeletal part

0.32

GO:0004553

sp|Q3KQV3|ZN792_HUMAN
Zinc finger protein 792
Search

0.65	Zinc finger protein 792

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.39	GO:0072707	cellular response to sodium dodecyl sulfate
0.38	GO:0045654	positive regulation of megakaryocyte differentiation
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:0048523	negative regulation of cellular process
0.38	GO:0045648	positive regulation of erythrocyte differentiation
0.37	GO:1901989	positive regulation of cell cycle phase transition
0.37	GO:0010558	negative regulation of macromolecule biosynthetic process

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0042802	identical protein binding
0.39	GO:0003700	DNA binding transcription factor activity
0.36	GO:0016758	transferase activity, transferring hexosyl groups

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part
0.30	GO:0016020	membrane

0.36

GO:0016758

sp|Q3KQV9|UAP1L_HUMAN
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
Search

UAP1L1

0.97	UDP-N-acetylglucosamine pyrophosphorylase 1 like 1

0.47	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.46	GO:0046349	amino sugar biosynthetic process
0.45	GO:0009226	nucleotide-sugar biosynthetic process
0.35	GO:0006491	N-glycan processing
0.34	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.33	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0006508	proteolysis

0.75	GO:0070569	uridylyltransferase activity
0.38	GO:0042802	identical protein binding
0.36	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0038062	protein tyrosine kinase collagen receptor activity
0.34	GO:0030246	carbohydrate binding
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.45	GO:0005829	cytosol
0.37	GO:0005654	nucleoplasm
0.35	GO:0005886	plasma membrane
0.34	GO:0000139	Golgi membrane
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.36	EC:3.2.1.113	GO:0004571
0.36	KEGG:R05982 KEGG:R06722	GO:0004571

sp|Q3KQZ1|S2535_HUMAN
Solute carrier family 25 member 35
Search

SLC25A35

0.88	LOW QUALITY PROTEIN: solute carrier family 25 member 35

0.49	GO:0006839	mitochondrial transport
0.40	GO:0055085	transmembrane transport
0.36	GO:0090226	regulation of microtubule nucleation by Ran protein signal transduction
0.36	GO:0098905	regulation of bundle of His cell action potential
0.36	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential
0.36	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction
0.36	GO:2000010	positive regulation of protein localization to cell surface
0.35	GO:0032527	protein exit from endoplasmic reticulum
0.35	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.35	GO:1903078	positive regulation of protein localization to plasma membrane

0.41	GO:0022857	transmembrane transporter activity
0.36	GO:0005087	Ran guanyl-nucleotide exchange factor activity
0.35	GO:0017080	sodium channel regulator activity
0.35	GO:0044325	ion channel binding
0.34	GO:0008565	protein transporter activity

0.47	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.35	GO:0014704	intercalated disc
0.35	GO:0005901	caveola
0.35	GO:0005791	rough endoplasmic reticulum
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q3KR16|PKHG6_HUMAN
Pleckstrin homology domain-containing family G member 6
Search

PLEKHG6

0.93	Pleckstrin homology and RhoGEF domain containing G6

0.76	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.48	GO:0035767	endothelial cell chemotaxis
0.35	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.34	GO:0007165	signal transduction
0.34	GO:0043065	positive regulation of apoptotic process
0.33	GO:0045087	innate immune response

0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0005096	GTPase activator activity
0.34	GO:0004871	signal transducer activity

0.60	GO:0030054	cell junction
0.59	GO:0005813	centrosome
0.46	GO:0030027	lamellipodium
0.46	GO:0030139	endocytic vesicle
0.40	GO:0032154	cleavage furrow
0.40	GO:0005902	microvillus
0.39	GO:0005819	spindle
0.38	GO:0005886	plasma membrane
0.36	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol

sp|Q3KR37|GRM1B_HUMAN
GRAM domain-containing protein 1B
Search

GRAMD1B

0.92	GRAM domain-containing protein 1B

0.30

GO:0044425

membrane part

sp|Q3KRA6|CB076_HUMAN
UPF0538 protein C2orf76
Search

sp|Q3KRA9|ALKB6_HUMAN
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6
Search

ALKBH6

0.63	Alpha-ketoglutarate-dependent dioxygenase alkB

0.52	GO:0055114	oxidation-reduction process
0.37	GO:0006508	proteolysis
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.55	GO:0051213	dioxygenase activity
0.48	GO:0008198	ferrous iron binding
0.38	GO:0008233	peptidase activity
0.37	GO:0030145	manganese ion binding
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0005515	protein binding
0.32	GO:0004930	G-protein coupled receptor activity

0.51	GO:0005925	focal adhesion
0.47	GO:0044428	nuclear part
0.45	GO:0031974	membrane-enclosed lumen
0.38	GO:0012505	endomembrane system
0.37	GO:0098796	membrane protein complex
0.37	GO:0031967	organelle envelope
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.38

GO:0008233

sp|Q3KRB8|RHGBB_HUMAN
Rho GTPase-activating protein 11B
Search

0.70	Rho GTPase-activating protein 11B

0.61	GO:0007165	signal transduction
0.47	GO:0043547	positive regulation of GTPase activity
0.37	GO:0051056	regulation of small GTPase mediated signal transduction
0.36	GO:0021987	cerebral cortex development

0.47

GO:0005096

GTPase activator activity

0.41	GO:0030141	secretory granule
0.36	GO:0005829	cytosol
0.32	GO:0005856	cytoskeleton
0.30	GO:0044425	membrane part

sp|Q3L8U1|CHD9_HUMAN
Chromodomain-helicase-DNA-binding protein 9
Search

CHD9

0.91	Chromodomain-helicase-DNA-binding protein 9

0.38	GO:0006325	chromatin organization
0.37	GO:0019216	regulation of lipid metabolic process
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0021545	cranial nerve development
0.35	GO:0042472	inner ear morphogenesis
0.35	GO:0043412	macromolecule modification
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0060041	retina development in camera-type eye
0.35	GO:0010468	regulation of gene expression

0.57	GO:0016817	hydrolase activity, acting on acid anhydrides
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.34	GO:1990841	promoter-specific chromatin binding
0.34	GO:0003729	mRNA binding
0.33	GO:0001067	regulatory region nucleic acid binding

0.58	GO:0005634	nucleus
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.32	GO:0043234	protein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.57

EC:3.6

GO:0016817

sp|Q3LFD5|UBP41_HUMAN
Putative ubiquitin carboxyl-terminal hydrolase 41
Search

USP18

0.97	Ubl carboxyl-terminal hydrolase 18

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.49	GO:0050727	regulation of inflammatory response
0.43	GO:0035634	response to stilbenoid
0.37	GO:0060338	regulation of type I interferon-mediated signaling pathway

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.48	GO:0019785	ISG15-specific protease activity
0.37	GO:0005515	protein binding

0.42	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0036459

sp|Q3LHN0|KR251_HUMAN
Keratin-associated protein 25-1
Search

KRTAP25-1

0.86	Keratin-associated protein 25-1

0.86

GO:0031424

keratinization

0.79	GO:0005882	intermediate filament
0.68	GO:0005829	cytosol

sp|Q3LHN1|KR213_HUMAN
Keratin-associated protein 21-3
Search

KRTAP21-3

0.83	Glycine/tyrosine-rich keratin-associated protein 22-1

0.82

GO:0031424

keratinization

0.73	GO:0005882	intermediate filament
0.64	GO:0005829	cytosol

sp|Q3LHN2|KR192_HUMAN
Keratin-associated protein 19-2
Search

0.93	Keratin associated protein 19-2

sp|Q3LI54|KR198_HUMAN
Keratin-associated protein 19-8
Search

0.95	Keratin-associated protein 6-3

0.61	GO:0031424	keratinization
0.40	GO:0043480	pigment accumulation in tissues
0.40	GO:0031077	post-embryonic camera-type eye development
0.39	GO:0001942	hair follicle development
0.38	GO:0048589	developmental growth
0.38	GO:0008283	cell proliferation
0.37	GO:0051726	regulation of cell cycle
0.35	GO:0007165	signal transduction

0.40	GO:0005515	protein binding
0.37	GO:0005198	structural molecule activity

0.65	GO:0005882	intermediate filament
0.50	GO:0005829	cytosol
0.37	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|Q3LI58|KR211_HUMAN
Keratin-associated protein 21-1
Search

0.95	High glycine/tyrosine keratin associated protein 6-L

0.52	GO:0043588	skin development
0.52	GO:0008544	epidermis development
0.49	GO:0060429	epithelium development
0.45	GO:0043480	pigment accumulation in tissues
0.45	GO:0030154	cell differentiation
0.44	GO:0031077	post-embryonic camera-type eye development
0.43	GO:0022405	hair cycle process
0.41	GO:0048589	developmental growth
0.41	GO:0008283	cell proliferation
0.40	GO:0051726	regulation of cell cycle

0.41	GO:0005200	structural constituent of cytoskeleton
0.39	GO:0008061	chitin binding
0.33	GO:0003676	nucleic acid binding

0.72	GO:0005882	intermediate filament
0.43	GO:0005829	cytosol
0.38	GO:0071986	Ragulator complex
0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q3LI59|KR212_HUMAN
Keratin-associated protein 21-2
Search

0.95	High glycine/tyrosine keratin associated protein 6-L

0.53	GO:0043588	skin development
0.53	GO:0008544	epidermis development
0.50	GO:0060429	epithelium development
0.46	GO:0030154	cell differentiation
0.43	GO:0043480	pigment accumulation in tissues
0.43	GO:0031077	post-embryonic camera-type eye development
0.41	GO:0022405	hair cycle process
0.40	GO:0048589	developmental growth
0.40	GO:0008283	cell proliferation
0.40	GO:0016560	protein import into peroxisome matrix, docking

0.34

GO:0005198

structural molecule activity

0.74	GO:0005882	intermediate filament
0.45	GO:0005829	cytosol
0.39	GO:0005777	peroxisome
0.30	GO:0016020	membrane

sp|Q3LI60|KR203_HUMAN
Keratin-associated protein 20-3
Search

0.86	Keratin associated protein 6-2

0.79

GO:0005882

intermediate filament

sp|Q3LI61|KR202_HUMAN
Keratin-associated protein 20-2
Search

0.97	Keratin-associated protein 6-3

0.55	GO:0031424	keratinization
0.45	GO:0007218	neuropeptide signaling pathway
0.38	GO:0045226	extracellular polysaccharide biosynthetic process
0.37	GO:0009103	lipopolysaccharide biosynthetic process
0.37	GO:0050829	defense response to Gram-negative bacterium
0.37	GO:0050832	defense response to fungus
0.36	GO:0031640	killing of cells of other organism
0.35	GO:0018108	peptidyl-tyrosine phosphorylation

0.36	GO:0003723	RNA binding
0.36	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.35	GO:0005515	protein binding
0.35	GO:0003690	double-stranded DNA binding
0.33	GO:0016787	hydrolase activity

0.65	GO:0005882	intermediate filament
0.46	GO:0005829	cytosol
0.36	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.36

EC:2.7.10.2

GO:0004715

sp|Q3LI62|KR204_HUMAN
Putative keratin-associated protein 20-4
Search

KRTAP20-4

0.10	Putative keratin-associated protein 20-4

0.79

GO:0005882

intermediate filament

sp|Q3LI63|KR201_HUMAN
Keratin-associated protein 20-1
Search

0.97	Truncated keratin associated protein 6

0.50	GO:0031424	keratinization
0.40	GO:0070830	bicellular tight junction assembly
0.37	GO:0007010	cytoskeleton organization
0.36	GO:0010466	negative regulation of peptidase activity

0.39	GO:0003676	nucleic acid binding
0.38	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0030414	peptidase inhibitor activity

0.68	GO:0005882	intermediate filament
0.43	GO:0005829	cytosol
0.39	GO:0005923	bicellular tight junction
0.39	GO:0019013	viral nucleocapsid
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q3LI64|KRA61_HUMAN
Keratin-associated protein 6-1
Search

0.95	Truncated keratin associated protein 6

0.79

GO:0005882

intermediate filament

sp|Q3LI66|KRA62_HUMAN
Keratin-associated protein 6-2
Search

0.94	Truncated keratin associated protein 6

0.79

GO:0005882

intermediate filament

sp|Q3LI67|KRA63_HUMAN
Keratin-associated protein 6-3
Search

0.96	Truncated keratin associated protein 6

0.79

GO:0005882

intermediate filament

sp|Q3LI68|KR222_HUMAN
Keratin-associated protein 22-2
Search

KRTAP22-2

0.95	Keratin associated protein 22-2

sp|Q3LI70|KR196_HUMAN
Keratin-associated protein 19-6
Search

0.91	High tyrosine-glycine keratin-associated protein 19.1

0.66	GO:0031424	keratinization
0.44	GO:0016043	cellular component organization
0.43	GO:0015919	peroxisomal membrane transport
0.42	GO:0044743	protein transmembrane import into intracellular organelle
0.41	GO:0065002	intracellular protein transmembrane transport
0.40	GO:0006605	protein targeting
0.38	GO:0030001	metal ion transport
0.38	GO:0044085	cellular component biogenesis
0.37	GO:0009405	pathogenesis

0.43	GO:0005200	structural constituent of cytoskeleton
0.41	GO:0030280	structural constituent of epidermis
0.39	GO:0004386	helicase activity
0.39	GO:0005515	protein binding
0.37	GO:0030246	carbohydrate binding
0.37	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0046872	metal ion binding

0.67	GO:0005882	intermediate filament
0.54	GO:0005829	cytosol
0.42	GO:0005923	bicellular tight junction
0.41	GO:0042579	microbody
0.40	GO:0001533	cornified envelope
0.30	GO:0016021	integral component of membrane

sp|Q3LI72|KR195_HUMAN
Keratin-associated protein 19-5
Search

0.97	High tyrosine-glycine keratin-associated protein 19.1

0.55	GO:0031424	keratinization
0.36	GO:0046379	extracellular polysaccharide metabolic process
0.35	GO:0009103	lipopolysaccharide biosynthetic process
0.35	GO:0009405	pathogenesis

0.39	GO:0005515	protein binding
0.37	GO:0030246	carbohydrate binding
0.34	GO:0005198	structural molecule activity

0.74	GO:0005882	intermediate filament
0.47	GO:0005829	cytosol
0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q3LI73|KR194_HUMAN
Keratin-associated protein 19-4
Search

0.96	High tyrosine-glycine keratin-associated protein 19.1

0.68

GO:0031424

keratinization

0.39	GO:0005515	protein binding
0.39	GO:0042302	structural constituent of cuticle

0.71	GO:0005882	intermediate filament
0.55	GO:0005829	cytosol
0.38	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|Q3LI76|KR151_HUMAN
Keratin-associated protein 15-1
Search

0.97	Keratin-associated protein 14

0.64

GO:0031424

keratinization

0.39

GO:0005515

protein binding

0.77	GO:0005882	intermediate filament
0.53	GO:0005829	cytosol

sp|Q3LI77|KR134_HUMAN
Keratin-associated protein 13-4
Search

0.97	Keratin-associated protein 14

0.58	GO:0031424	keratinization
0.36	GO:0042633	hair cycle
0.36	GO:0007568	aging

0.38

GO:0005515

protein binding

0.76	GO:0005882	intermediate filament
0.49	GO:0005829	cytosol

sp|Q3LI81|KR271_HUMAN
Keratin-associated protein 27-1
Search

KRTAP27-1

0.97	Keratin associated protein 27-1

sp|Q3LI83|KR241_HUMAN
Keratin-associated protein 24-1
Search

KRTAP24-1

0.89	Keratin-associated protein 24-1

0.49

GO:0031424

keratinization

0.62

GO:0005198

structural molecule activity

0.83	GO:0045095	keratin filament
0.42	GO:0005829	cytosol

sp|Q3LIE5|ADPRM_HUMAN
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Search

ADPRM

0.96	Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase

0.38	GO:0034656	nucleobase-containing small molecule catabolic process
0.33	GO:0006468	protein phosphorylation

0.50	GO:0016787	hydrolase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0003677	DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.50

GO:0016787

sp|Q3LXA3|TKFC_HUMAN
Triokinase/FMN cyclase
Search

TKFC

0.50	Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase

0.76	GO:0006071	glycerol metabolic process
0.61	GO:0039534	negative regulation of MDA-5 signaling pathway
0.57	GO:0016310	phosphorylation
0.39	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
0.35	GO:0045087	innate immune response
0.34	GO:0046031	ADP metabolic process
0.34	GO:0006090	pyruvate metabolic process
0.34	GO:0019362	pyridine nucleotide metabolic process
0.33	GO:0046034	ATP metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.79	GO:0004371	glycerone kinase activity
0.62	GO:0050354	triokinase activity
0.62	GO:0034012	FAD-AMP lyase (cyclizing) activity
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.31	GO:0016491	oxidoreductase activity

0.37	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.33	GO:0030127	COPII vesicle coat

0.79	EC:2.7.1.29	GO:0004371
0.79	KEGG:R01011	GO:0004371

sp|Q3MHD2|LSM12_HUMAN
Protein LSM12 homolog
Search

0.45	GO:0070932	histone H3 deacetylation
0.45	GO:0040029	regulation of gene expression, epigenetic
0.40	GO:0006749	glutathione metabolic process
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.46	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.41	GO:0004364	glutathione transferase activity

0.39	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.46

GO:0032041

sp|Q3MII6|TBC25_HUMAN
TBC1 domain family member 25
Search

TBC1D25

0.96	Ornithine aminotransferase-like 1 (Predicted)

0.81	GO:1901096	regulation of autophagosome maturation
0.71	GO:0043547	positive regulation of GTPase activity
0.63	GO:0031338	regulation of vesicle fusion
0.54	GO:0006886	intracellular protein transport
0.42	GO:0006914	autophagy
0.40	GO:0016125	sterol metabolic process

0.72	GO:0005096	GTPase activator activity
0.61	GO:0017137	Rab GTPase binding
0.46	GO:0008483	transaminase activity
0.42	GO:0047750	cholestenol delta-isomerase activity
0.34	GO:0003723	RNA binding

0.78	GO:0005776	autophagosome
0.53	GO:0012505	endomembrane system
0.40	GO:0031410	cytoplasmic vesicle
0.30	GO:0016020	membrane

0.46

EC:2.6.1

GO:0008483

sp|Q3MIN7|RGL3_HUMAN
Ral guanine nucleotide dissociation stimulator-like 3
Search

RGL3

0.76	ral guanine nucleotide dissociation stimulator

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.34	GO:0070286	axonemal dynein complex assembly
0.34	GO:0003341	cilium movement
0.34	GO:0019221	cytokine-mediated signaling pathway

0.76	GO:0008321	Ral guanyl-nucleotide exchange factor activity
0.42	GO:0030695	GTPase regulator activity
0.34	GO:0004896	cytokine receptor activity

0.45	GO:0005622	intracellular
0.44	GO:0005903	brush border
0.37	GO:0043227	membrane-bounded organelle
0.34	GO:0005929	cilium
0.30	GO:0016020	membrane

sp|Q3MIP1|IPIL2_HUMAN
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2
Search

ITPRIPL2

0.97	Inositol 1,4,5-trisphosphate receptor interacting protein like 2

0.30

GO:0044425

membrane part

sp|Q3MIR4|CC50B_HUMAN
Cell cycle control protein 50B
Search

TMEM30B

0.86	Cell cycle control protein 50B

0.58	GO:0015914	phospholipid transport
0.56	GO:0070863	positive regulation of protein exit from endoplasmic reticulum
0.44	GO:0071705	nitrogen compound transport
0.36	GO:0036010	protein localization to endosome
0.36	GO:0010976	positive regulation of neuron projection development
0.35	GO:0034204	lipid translocation
0.35	GO:0006855	drug transmembrane transport
0.33	GO:0017148	negative regulation of translation

0.58	GO:0015247	aminophospholipid transmembrane transporter activity
0.34	GO:0008483	transaminase activity
0.34	GO:0030597	RNA glycosylase activity
0.34	GO:0030170	pyridoxal phosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0140102	catalytic activity, acting on a rRNA

0.35	GO:0005886	plasma membrane
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.34

EC:2.6.1

GO:0008483

sp|Q3MIS6|ZN528_HUMAN
Zinc finger protein 528
Search

0.80	Zinc finger protein 813

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.40	GO:0097659	nucleic acid-templated transcription
0.38	GO:0010467	gene expression
0.38	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part

sp|Q3MIT2|PUS10_HUMAN
Putative tRNA pseudouridine synthase Pus10
Search

PUS10

0.91	Pseudouridylate synthase 10

0.72	GO:0001522	pseudouridine synthesis
0.48	GO:0006400	tRNA modification

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding

0.72

EC:5.4.99.12

GO:0009982

sp|Q3MIV0|KR221_HUMAN
Keratin-associated protein 22-1
Search

KRTAP22-1

0.88	Keratin-associated protein 22-1

0.86

GO:0031424

keratinization

0.79	GO:0005882	intermediate filament
0.68	GO:0005829	cytosol

sp|Q3MIW9|DPCR1_HUMAN
Diffuse panbronchiolitis critical region protein 1
Search

DPCR1

0.97	Diffuse panbronchiolitis critical region protein 1

0.58

GO:1903955

positive regulation of protein targeting to mitochondrion

0.30

GO:0016021

integral component of membrane

sp|Q3MIX3|ADCK5_HUMAN
Uncharacterized aarF domain-containing protein kinase 5
Search

ADCK5

0.93	AarF domain-containing protein kinase

0.53	GO:0016310	phosphorylation
0.39	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process
0.34	GO:0055088	lipid homeostasis
0.34	GO:0007005	mitochondrion organization
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0016301	kinase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0004497	monooxygenase activity
0.33	GO:0020037	heme binding

0.38	GO:0005739	mitochondrion
0.34	GO:0005576	extracellular region
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016773

sp|Q3MJ13|WDR72_HUMAN
WD repeat-containing protein 72
Search

WDR72

0.97	LOW QUALITY PROTEIN: WD repeat-containing protein 72

0.82

GO:0070166

enamel mineralization

0.69	GO:0005768	endosome
0.30	GO:0044425	membrane part

sp|Q3MJ16|PA24E_HUMAN
Cytosolic phospholipase A2 epsilon
Search

PLA2G4E

0.66	Cytosolic phospholipase A2 epsilon

0.80	GO:0009395	phospholipid catabolic process
0.42	GO:0046503	glycerolipid catabolic process
0.40	GO:0006650	glycerophospholipid metabolic process
0.37	GO:0097164	ammonium ion metabolic process
0.36	GO:0006575	cellular modified amino acid metabolic process
0.34	GO:0045017	glycerolipid biosynthetic process
0.34	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0007567	parturition
0.34	GO:0019369	arachidonic acid metabolic process
0.34	GO:0008654	phospholipid biosynthetic process

0.83	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.83	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.80	GO:0004623	phospholipase A2 activity
0.53	GO:0046872	metal ion binding
0.39	GO:0004622	lysophospholipase activity
0.38	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.33	GO:0005544	calcium-dependent phospholipid binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding

0.48	GO:0005737	cytoplasm
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0005576	extracellular region
0.32	GO:0031975	envelope

0.80

EC:3.1.1.4

GO:0004623

sp|Q3MJ40|C144B_HUMAN
Coiled-coil domain-containing protein 144B
Search

0.76	Coiled-coil domain-containing protein 144A

sp|Q3MJ62|ZSC23_HUMAN
Zinc finger and SCAN domain-containing protein 23
Search

0.90	Zinc finger protein with KRAB and SCAN domains 8

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.41	GO:0015074	DNA integration
0.33	GO:0006898	receptor-mediated endocytosis

0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0046872	metal ion binding
0.49	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.33	GO:0005044	scavenger receptor activity

0.60	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q3MUY2|PIGY_HUMAN
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
Search

PIGY

0.97	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

0.78

GO:0006506

GPI anchor biosynthetic process

0.59

GO:0016757

transferase activity, transferring glycosyl groups

0.86	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.59

GO:0016757

sp|Q3SX64|OD3L2_HUMAN
Outer dense fiber protein 3-like protein 2
Search

ODF3L2

0.90	Outer dense fiber of sperm tails 3 like 2

0.45	GO:0007605	sensory perception of sound
0.44	GO:0007286	spermatid development
0.41	GO:0000187	activation of MAPK activity
0.37	GO:0035556	intracellular signal transduction

0.41

GO:0030971

receptor tyrosine kinase binding

0.78

GO:0005881

cytoplasmic microtubule

sp|Q3SXM0|DC4L1_HUMAN
DDB1- and CUL4-associated factor 4-like protein 1
Search

DCAF4

0.96	WD repeat-containing protein 21B

0.65	GO:0008380	RNA splicing
0.43	GO:0016567	protein ubiquitination
0.41	GO:0043687	post-translational protein modification

0.53

GO:0003723

RNA binding

0.74	GO:0071011	precatalytic spliceosome
0.73	GO:0005682	U5 snRNP
0.72	GO:0071013	catalytic step 2 spliceosome
0.70	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.39	GO:0005654	nucleoplasm

sp|Q3SXM5|HSDL1_HUMAN
Inactive hydroxysteroid dehydrogenase-like protein 1
Search

HSDL1

0.96	Hydroxysteroid dehydrogenase like 1

0.47	GO:0055114	oxidation-reduction process
0.39	GO:0006703	estrogen biosynthetic process
0.37	GO:0010811	positive regulation of cell-substrate adhesion
0.37	GO:0030198	extracellular matrix organization
0.36	GO:0006633	fatty acid biosynthetic process
0.33	GO:0006508	proteolysis
0.32	GO:0007154	cell communication

0.48	GO:0016491	oxidoreductase activity
0.38	GO:0001968	fibronectin binding
0.37	GO:0005518	collagen binding
0.37	GO:0008201	heparin binding
0.33	GO:0004252	serine-type endopeptidase activity

0.49	GO:0005739	mitochondrion
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0005922	connexin complex
0.30	GO:0016021	integral component of membrane

0.48

GO:0016491

sp|Q3SXP7|K1644_HUMAN
Uncharacterized protein KIAA1644
Search

CACNA2D3

0.97	Calcium channel, voltage-dependent, alpha 2/delta subunit 3 (Fragment)

0.30

GO:0044425

membrane part

sp|Q3SXR2|CC036_HUMAN
Uncharacterized protein C3orf36
Search

sp|Q3SXY7|LRIT3_HUMAN
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3
Search

LRIT3

0.95	LOW QUALITY PROTEIN: leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3

0.63	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.58	GO:0007601	visual perception
0.38	GO:0018298	protein-chromophore linkage
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0001522	pseudouridine synthesis
0.35	GO:0042254	ribosome biogenesis
0.32	GO:0007413	axonal fasciculation
0.32	GO:0042552	myelination
0.31	GO:0007155	cell adhesion

0.39	GO:0009881	photoreceptor activity
0.37	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005509	calcium ion binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0043204	perikaryon
0.39	GO:0030425	dendrite
0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031429	box H/ACA snoRNP complex
0.31	GO:0005887	integral component of plasma membrane

sp|Q3SXY8|AR13B_HUMAN
ADP-ribosylation factor-like protein 13B
Search

ARL13B

0.95	ADP ribosylation factor like GTPase 13B

0.62	GO:0021943	formation of radial glial scaffolds
0.61	GO:0021830	interneuron migration from the subpallium to the cortex
0.60	GO:0070986	left/right axis specification
0.58	GO:0021532	neural tube patterning
0.57	GO:0001947	heart looping
0.57	GO:1905515	non-motile cilium assembly
0.57	GO:0007224	smoothened signaling pathway
0.56	GO:0009953	dorsal/ventral pattern formation
0.43	GO:0035845	photoreceptor cell outer segment organization
0.41	GO:0010226	response to lithium ion

0.63	GO:0032550	purine ribonucleoside binding
0.63	GO:0019001	guanyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0030742	GTP-dependent protein binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.58	GO:0060170	ciliary membrane
0.56	GO:0005930	axoneme
0.55	GO:0031514	motile cilium
0.37	GO:0097544	ciliary shaft
0.36	GO:0097546	ciliary base
0.35	GO:0097731	9+0 non-motile cilium
0.33	GO:0005840	ribosome

0.33

GO:0008168

sp|Q3SXZ3|ZN718_HUMAN
Zinc finger protein 718
Search

0.83	Zinc finger protein 626

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:0070895	negative regulation of transposon integration
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0035108	limb morphogenesis

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|Q3SXZ7|TTLL9_HUMAN
Probable tubulin polyglutamylase TTLL9
Search

TTLL9

0.88	Tubulin Tyrosine Ligase Like

0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.33	GO:0007165	signal transduction
0.33	GO:0034220	ion transmembrane transport

0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016874	ligase activity
0.35	GO:0005230	extracellular ligand-gated ion channel activity
0.34	GO:0004888	transmembrane signaling receptor activity

0.36	GO:0005929	cilium
0.36	GO:0005874	microtubule
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016874

sp|Q3SY00|T10IP_HUMAN
Testis-specific protein 10-interacting protein
Search

TSGA10IP

0.97	Testis specific 10 interacting protein

sp|Q3SY05|CA157_HUMAN
Putative uncharacterized protein encoded by LINC00303
Search

sp|Q3SY17|S2552_HUMAN
Solute carrier family 25 member 52
Search

SLC25A51

0.97	Mitochondrial carrier triple repeat protein 1

0.48	GO:0006839	mitochondrial transport
0.39	GO:0055085	transmembrane transport
0.33	GO:0006379	mRNA cleavage
0.32	GO:0007015	actin filament organization
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006835	dicarboxylic acid transport
0.32	GO:0016310	phosphorylation

0.40	GO:0022857	transmembrane transporter activity
0.34	GO:0005198	structural molecule activity
0.33	GO:0003785	actin monomer binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0004386	helicase activity
0.32	GO:0019205	nucleobase-containing compound kinase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005739	mitochondrion
0.42	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7.6

GO:0003899

sp|Q3SY46|KR133_HUMAN
Keratin-associated protein 13-3
Search

0.97	Keratin-associated protein 14

0.65

GO:0031424

keratinization

0.42

GO:0005515

protein binding

0.75	GO:0005882	intermediate filament
0.53	GO:0005829	cytosol

sp|Q3SY52|ZIK1_HUMAN
Zinc finger protein interacting with ribonucleoprotein K
Search

0.70	zinc finger protein interacting with ribonucleoprotein K

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.35	GO:0016503	pheromone receptor activity
0.35	GO:0003700	DNA binding transcription factor activity

0.45	GO:0019013	viral nucleocapsid
0.44	GO:0005622	intracellular
0.41	GO:1990904	ribonucleoprotein complex
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q3SY56|SP6_HUMAN
Transcription factor Sp6
Search

SP6

0.70	Sp6 transcription factor

0.63	GO:0042481	regulation of odontogenesis
0.58	GO:0008284	positive regulation of cell proliferation
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0006366	transcription by RNA polymerase II
0.34	GO:0009887	animal organ morphogenesis
0.34	GO:0035218	leg disc development
0.34	GO:0036342	post-anal tail morphogenesis
0.34	GO:0035120	post-embryonic appendage morphogenesis
0.34	GO:0035114	imaginal disc-derived appendage morphogenesis
0.33	GO:0048707	instar larval or pupal morphogenesis

0.51	GO:0003676	nucleic acid binding
0.47	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0016805	dipeptidase activity
0.32	GO:0016301	kinase activity

0.49	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

EC:3.4.13

GO:0016805

sp|Q3SY69|AL1L2_HUMAN
Mitochondrial 10-formyltetrahydrofolate dehydrogenase
Search

ALDH1L2

0.93	Mitochondrial 10-formyltetrahydrofolate dehydrogenase

0.85	GO:0009258	10-formyltetrahydrofolate catabolic process
0.69	GO:0006730	one-carbon metabolic process
0.51	GO:0055114	oxidation-reduction process
0.48	GO:0009058	biosynthetic process
0.45	GO:0048885	neuromast deposition
0.43	GO:0048703	embryonic viscerocranium morphogenesis
0.43	GO:0001755	neural crest cell migration
0.42	GO:0007369	gastrulation
0.42	GO:0007507	heart development
0.36	GO:0046655	folic acid metabolic process

0.85	GO:0016155	formyltetrahydrofolate dehydrogenase activity
0.71	GO:0016742	hydroxymethyl-, formyl- and related transferase activity
0.67	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.35	GO:0016787	hydrolase activity

0.47	GO:0005737	cytoplasm
0.44	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.85	EC:1.5.1.6	GO:0016155
0.85	KEGG:R00941	GO:0016155

sp|Q3SY77|UD3A2_HUMAN
UDP-glucuronosyltransferase 3A2
Search

0.51	UDP-glucuronosyltransferase

0.48	GO:0071412	cellular response to genistein
0.36	GO:0052695	cellular glucuronidation
0.34	GO:0070980	biphenyl catabolic process
0.34	GO:0030573	bile acid catabolic process
0.34	GO:0071394	cellular response to testosterone stimulus
0.34	GO:0071361	cellular response to ethanol
0.33	GO:0071378	cellular response to growth hormone stimulus
0.33	GO:0071385	cellular response to glucocorticoid stimulus
0.33	GO:0032496	response to lipopolysaccharide
0.33	GO:0016042	lipid catabolic process

0.78

GO:0015020

glucuronosyltransferase activity

0.45	GO:0043541	UDP-N-acetylglucosamine transferase complex
0.34	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:2.4.1.17

GO:0015020

sp|Q3SY84|K2C71_HUMAN
Keratin, type II cytoskeletal 71
Search

0.95	Keratin, type II cytoskeletal 71

0.57	GO:0045104	intermediate filament cytoskeleton organization
0.53	GO:0031069	hair follicle morphogenesis
0.47	GO:0097435	supramolecular fiber organization
0.40	GO:0070268	cornification
0.36	GO:0050680	negative regulation of epithelial cell proliferation

0.62	GO:0005198	structural molecule activity
0.48	GO:1990254	keratin filament binding

0.83	GO:0045095	keratin filament
0.41	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.35	GO:0009986	cell surface
0.34	GO:0005634	nucleus

sp|Q3SY89|ELB3B_HUMAN
Elongin-A3 member B
Search

0.95	Elongin-A3 member B

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.53	GO:0006368	transcription elongation from RNA polymerase II promoter
0.46	GO:0006414	translational elongation
0.35	GO:0032784	regulation of DNA-templated transcription, elongation
0.34	GO:0055114	oxidation-reduction process
0.32	GO:0006402	mRNA catabolic process
0.32	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.32	GO:0006364	rRNA processing
0.32	GO:0008033	tRNA processing
0.31	GO:0006508	proteolysis

0.46	GO:0003746	translation elongation factor activity
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0003690	double-stranded DNA binding
0.32	GO:0016787	hydrolase activity
0.32	GO:0000287	magnesium ion binding
0.31	GO:0008270	zinc ion binding
0.31	GO:0140098	catalytic activity, acting on RNA
0.31	GO:0140096	catalytic activity, acting on a protein

0.84	GO:0070449	elongin complex
0.35	GO:0005840	ribosome
0.35	GO:0005615	extracellular space
0.32	GO:0009898	cytoplasmic side of plasma membrane

0.34

GO:0016491

sp|Q3SYA9|P12L1_HUMAN
Putative POM121-like protein 1
Search

0.45	GO:0006606	protein import into nucleus
0.44	GO:0006405	RNA export from nucleus
0.41	GO:0035461	vitamin transmembrane transport

0.50	GO:0005515	protein binding
0.47	GO:0008139	nuclear localization sequence binding
0.45	GO:0017056	structural constituent of nuclear pore
0.40	GO:0090482	vitamin transmembrane transporter activity
0.39	GO:0003774	motor activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0044613	nuclear pore central transport channel
0.48	GO:0044615	nuclear pore nuclear basket
0.40	GO:0016459	myosin complex
0.38	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q3SYB3|FX4L6_HUMAN
Forkhead box protein D4-like 6
Search

0.92	Forkhead box protein D4

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0030154	cell differentiation
0.51	GO:0009653	anatomical structure morphogenesis
0.44	GO:0006351	transcription, DNA-templated
0.42	GO:0051254	positive regulation of RNA metabolic process
0.42	GO:0010557	positive regulation of macromolecule biosynthetic process
0.42	GO:0031328	positive regulation of cellular biosynthetic process
0.40	GO:0072127	renal capsule development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.40	GO:0008301	DNA binding, bending
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0001106	RNA polymerase II transcription corepressor activity

0.61

GO:0005634

nucleus

sp|Q3SYC2|MOGT2_HUMAN
2-acylglycerol O-acyltransferase 2
Search

MOGAT2

0.92	Monoacylglycerol O-acyltransferase 2

0.58	GO:0006651	diacylglycerol biosynthetic process
0.55	GO:0050892	intestinal absorption
0.53	GO:0019432	triglyceride biosynthetic process
0.44	GO:0001878	response to yeast
0.37	GO:0006071	glycerol metabolic process
0.36	GO:0046462	monoacylglycerol metabolic process

0.64

GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

0.48	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016747

sp|Q3SYF9|KR197_HUMAN
Keratin-associated protein 19-7
Search

0.97	High tyrosine-glycine keratin-associated protein 19.1

0.66	GO:0031424	keratinization
0.41	GO:0007304	chorion-containing eggshell formation

0.42	GO:0005213	structural constituent of chorion
0.41	GO:0005515	protein binding

0.67	GO:0005882	intermediate filament
0.53	GO:0005829	cytosol
0.41	GO:0042600	chorion
0.30	GO:0031224	intrinsic component of membrane

sp|Q3SYG4|PTHB1_HUMAN
Protein PTHB1
Search

BBS9

0.96	Bardet-Biedl syndrome 9

0.65	GO:0061512	protein localization to cilium
0.64	GO:0060271	cilium assembly
0.60	GO:0045444	fat cell differentiation
0.51	GO:0097205	renal filtration
0.50	GO:0010842	retina layer formation
0.50	GO:0048793	pronephros development
0.49	GO:0001843	neural tube closure
0.48	GO:0007369	gastrulation

0.84	GO:0034464	BBSome
0.66	GO:0000242	pericentriolar material
0.66	GO:0034451	centriolar satellite
0.63	GO:0035869	ciliary transition zone
0.30	GO:0016020	membrane

sp|Q3T8J9|GON4L_HUMAN
GON-4-like protein
Search

GON4L

0.96	Gon-4 like

0.85	GO:0030183	B cell differentiation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0008283	cell proliferation
0.35	GO:0051726	regulation of cell cycle
0.35	GO:0006351	transcription, DNA-templated

0.81	GO:0003714	transcription corepressor activity
0.52	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.36	GO:0033202	DNA helicase complex
0.35	GO:0005694	chromosome
0.35	GO:1904949	ATPase complex
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q3T906|GNPTA_HUMAN
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
Search

GNPTAB

0.96	N-acetylglucosamine-1-phosphate transferase alpha and beta subunits

0.66	GO:0016256	N-glycan processing to lysosome
0.63	GO:0033299	secretion of lysosomal enzymes
0.59	GO:0007040	lysosome organization
0.54	GO:0046835	carbohydrate phosphorylation

0.68	GO:0005509	calcium ion binding
0.65	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
0.34	GO:0005515	protein binding

0.54	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.65

EC:2.7.8.17

GO:0003976

sp|Q3V5L5|MGT5B_HUMAN
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
Search

MGAT5B

0.97	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

0.80

GO:0006487

protein N-linked glycosylation

0.86	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.50	GO:0005794	Golgi apparatus
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.4.1.155

GO:0030144

sp|Q3V6T2|GRDN_HUMAN
Girdin
Search

CCDC88A

0.89	Coiled-coil domain containing 88A

0.78	GO:0016477	cell migration
0.77	GO:0032956	regulation of actin cytoskeleton organization
0.71	GO:1903566	positive regulation of protein localization to cilium
0.68	GO:0032148	activation of protein kinase B activity
0.67	GO:0045724	positive regulation of cilium assembly
0.67	GO:0030032	lamellipodium assembly
0.64	GO:0031929	TOR signaling
0.63	GO:0010975	regulation of neuron projection development
0.60	GO:0006275	regulation of DNA replication
0.60	GO:0042127	regulation of cell proliferation

0.74	GO:0003779	actin binding
0.70	GO:0043422	protein kinase B binding
0.59	GO:0035091	phosphatidylinositol binding
0.59	GO:0008017	microtubule binding
0.59	GO:0042803	protein homodimerization activity
0.49	GO:0051959	dynein light intermediate chain binding

0.63	GO:0036064	ciliary basal body
0.63	GO:0030027	lamellipodium
0.63	GO:0005814	centriole
0.57	GO:0031410	cytoplasmic vesicle
0.56	GO:0005794	Golgi apparatus
0.56	GO:0005783	endoplasmic reticulum
0.54	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane
0.46	GO:0005813	centrosome

sp|Q3Y452|TDRG1_HUMAN
Testis development-related protein 1
Search

sp|Q3YBM2|T176B_HUMAN
Transmembrane protein 176B
Search

TMEM176B

0.97	Transmembrane protein 176B isoform a

0.73	GO:2001199	negative regulation of dendritic cell differentiation
0.44	GO:0030154	cell differentiation
0.39	GO:0009887	animal organ morphogenesis

0.35

GO:0005515

protein binding

0.47	GO:0031965	nuclear membrane
0.30	GO:0044425	membrane part

sp|Q3YBR2|TBRG1_HUMAN
Transforming growth factor beta regulator 1
Search

TBRG1

0.97	Transforming growth factor beta regulator

0.65	GO:1990173	protein localization to nucleoplasm
0.59	GO:0007050	cell cycle arrest
0.57	GO:0050821	protein stabilization
0.56	GO:0008285	negative regulation of cell proliferation
0.49	GO:0006260	DNA replication
0.43	GO:0006351	transcription, DNA-templated
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.34	GO:0035385	Roundabout signaling pathway

0.34

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.33	GO:0030424	axon
0.32	GO:0005737	cytoplasm

sp|Q3YEC7|RABL6_HUMAN
Rab-like protein 6
Search

RABL6

0.96	RAB, member RAS oncogene family like 6

0.37

GO:0006614

SRP-dependent cotranslational protein targeting to membrane

0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003924	GTPase activity
0.38	GO:0008312	7S RNA binding

0.73	GO:0005813	centrosome
0.65	GO:0005829	cytosol
0.58	GO:0005634	nucleus
0.38	GO:0048500	signal recognition particle

sp|Q3ZAQ7|VMA21_HUMAN
Vacuolar ATPase assembly integral membrane protein VMA21
Search

VMA21

0.82	Vacuolar ATPase assembly integral membrane protein VMA21

0.84	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.35	GO:0043462	regulation of ATPase activity

0.78	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.72	GO:0012507	ER to Golgi transport vesicle membrane
0.65	GO:0005789	endoplasmic reticulum membrane
0.50	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q3ZCM7|TBB8_HUMAN
Tubulin beta-8 chain
Search

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.39	GO:0001556	oocyte maturation
0.39	GO:0007143	female meiotic nuclear division
0.37	GO:0007435	salivary gland morphogenesis
0.37	GO:0070925	organelle assembly
0.35	GO:1902669	positive regulation of axon guidance
0.34	GO:0001764	neuron migration

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046982	protein heterodimerization activity

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.39	GO:0072687	meiotic spindle
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q3ZCN5|OTOGL_HUMAN
Otogelin-like protein
Search

OTOGL

0.57	Otogelin like

0.82	GO:0007605	sensory perception of sound
0.76	GO:0046373	L-arabinose metabolic process
0.62	GO:0008344	adult locomotory behavior
0.55	GO:0032474	otolith morphogenesis
0.50	GO:0048752	semicircular canal morphogenesis
0.46	GO:0035889	otolith tethering
0.41	GO:0048646	anatomical structure formation involved in morphogenesis

0.78	GO:0046556	alpha-L-arabinofuranosidase activity
0.49	GO:0005198	structural molecule activity

0.55	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.2.1.55

GO:0046556

sp|Q3ZCQ2|AX2R_HUMAN
Annexin-2 receptor
Search

ANXA2R

0.97	Annexin II receptor

0.65

GO:0060089

molecular transducer activity

sp|Q3ZCQ3|F174B_HUMAN
Membrane protein FAM174B
Search

FAM174B

0.97	Membrane protein FAM174B

0.30

GO:0044425

membrane part

sp|Q3ZCQ8|TIM50_HUMAN
Mitochondrial import inner membrane translocase subunit TIM50
Search

TIMM50

0.89	Translocase of inner mitochondrial membrane 50

0.63	GO:0015031	protein transport
0.55	GO:0001836	release of cytochrome c from mitochondria
0.53	GO:0007006	mitochondrial membrane organization
0.50	GO:0035335	peptidyl-tyrosine dephosphorylation
0.45	GO:1990542	mitochondrial transmembrane transport
0.44	GO:0072655	establishment of protein localization to mitochondrion
0.41	GO:0046907	intracellular transport

0.56	GO:0005134	interleukin-2 receptor binding
0.51	GO:0004722	protein serine/threonine phosphatase activity
0.50	GO:0004725	protein tyrosine phosphatase activity
0.49	GO:0043021	ribonucleoprotein complex binding
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0003723	RNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.51	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0004725

sp|Q3ZCT1|ZN260_HUMAN
Zinc finger protein 260
Search

ZNF260

0.85	Zinc finger domain-containing protein (Fragment)

0.50	GO:1903506	regulation of nucleic acid-templated transcription
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.38	GO:0007275	multicellular organism development
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0003006	developmental process involved in reproduction
0.33	GO:0009653	anatomical structure morphogenesis

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.45	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.48	GO:0005829	cytosol
0.48	GO:0031981	nuclear lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q3ZCT8|KBTBC_HUMAN
Kelch repeat and BTB domain-containing protein 12
Search

KBTBD12

0.97	Kelch repeat and BTB domain-containing protein 12

0.73

GO:0016567

protein ubiquitination

0.74

GO:0004842

ubiquitin-protein transferase activity

0.83

GO:0031463

Cul3-RING ubiquitin ligase complex

0.74

GO:0004842

sp|Q3ZCU0|YK006_HUMAN
Putative uncharacterized protein FLJ37770
Search

0.51	GO:0032502	developmental process
0.51	GO:0016579	protein deubiquitination
0.50	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.44	GO:1900037	regulation of cellular response to hypoxia
0.44	GO:0048642	negative regulation of skeletal muscle tissue development
0.44	GO:1904292	regulation of ERAD pathway
0.44	GO:1901799	negative regulation of proteasomal protein catabolic process
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0010033	response to organic substance

0.51	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.45	GO:0042803	protein homodimerization activity
0.44	GO:0051879	Hsp90 protein binding
0.44	GO:1990380	Lys48-specific deubiquitinase activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.39	GO:0003682	chromatin binding
0.38	GO:0001158	enhancer sequence-specific DNA binding
0.38	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.46	GO:0005654	nucleoplasm
0.42	GO:0033256	I-kappaB/NF-kappaB complex
0.42	GO:0005829	cytosol
0.41	GO:0012505	endomembrane system
0.39	GO:0031984	organelle subcompartment
0.39	GO:0005815	microtubule organizing center
0.37	GO:0035869	ciliary transition zone
0.37	GO:0005667	transcription factor complex
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane

0.51

GO:0036459

sp|Q3ZCV2|LEXM_HUMAN
Lymphocyte expansion molecule
Search

LEXM

0.97	Lymphocyte expansion molecule

0.61

GO:0005739

mitochondrion

sp|Q3ZCW2|LEGL_HUMAN
Galectin-related protein
Search

LGALSL

0.66

Galectin

0.38	GO:0015844	monoamine transport
0.37	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.33	GO:0006468	protein phosphorylation

0.69	GO:0030246	carbohydrate binding
0.37	GO:0008022	protein C-terminus binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0019899	enzyme binding

0.38	GO:0005622	intracellular
0.37	GO:0042734	presynaptic membrane
0.34	GO:0012505	endomembrane system
0.34	GO:0043227	membrane-bounded organelle

sp|Q3ZCX4|ZN568_HUMAN
Zinc finger protein 568
Search

ZNF510

0.71	Zinc finger protein 568

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0014022	neural plate elongation
0.39	GO:0060029	convergent extension involved in organogenesis
0.38	GO:0060028	convergent extension involved in axis elongation
0.38	GO:0060669	embryonic placenta morphogenesis
0.38	GO:0060027	convergent extension involved in gastrulation
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:1902679	negative regulation of RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.39	GO:0001222	transcription corepressor binding

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.36	GO:0017053	transcriptional repressor complex
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044422	organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q3ZLR7|SP201_HUMAN
Transcription factor SPT20 homolog-like 1
Search

SUPT20H

0.91	Suppressor of Ty 20

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:0045722	positive regulation of gluconeogenesis
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0010628	positive regulation of gene expression
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0007369	gastrulation
0.34	GO:0006914	autophagy

0.76	GO:0003712	transcription cofactor activity
0.33	GO:0005515	protein binding

0.80	GO:0000124	SAGA complex
0.50	GO:0001650	fibrillar center
0.34	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|Q3ZM63|Q3ZM63_HUMAN
Long intergenic non-protein coding RNA 633
Search

sp|Q400G9|AMZ1_HUMAN
Archaemetzincin-1
Search

AMZ1

0.97	Archaemetzincin-1

0.61

GO:0006508

proteolysis

0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding

sp|Q401N2|ZACN_HUMAN
Zinc-activated ligand-gated ion channel
Search

ZACN

0.97	Zinc-activated ligand-gated ion channel

0.79	GO:0010043	response to zinc ion
0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.44	GO:0006812	cation transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity
0.51	GO:0140135	mechanosensitive cation channel activity
0.37	GO:0008270	zinc ion binding

0.52	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q460N3|PAR15_HUMAN
Poly [ADP-ribose] polymerase 15
Search

PARP15

0.47	Poly [ADP-ribose] polymerase

0.65	GO:0070212	protein poly-ADP-ribosylation
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:1902216	positive regulation of interleukin-4-mediated signaling pathway
0.36	GO:0060331	negative regulation of response to interferon-gamma
0.36	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0060334	regulation of interferon-gamma-mediated signaling pathway
0.36	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.35	GO:0045087	innate immune response
0.35	GO:0001960	negative regulation of cytokine-mediated signaling pathway

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.60	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.56	GO:0070403	NAD+ binding
0.37	GO:0005515	protein binding
0.34	GO:0003676	nucleic acid binding

0.37	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.82

GO:0003950

sp|Q460N5|PAR14_HUMAN
Poly [ADP-ribose] polymerase 14
Search

PARP14

0.46	Poly [ADP-ribose] polymerase

0.57	GO:1902216	positive regulation of interleukin-4-mediated signaling pathway
0.56	GO:0060331	negative regulation of response to interferon-gamma
0.55	GO:0060334	regulation of interferon-gamma-mediated signaling pathway
0.54	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.53	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.53	GO:0006471	protein ADP-ribosylation
0.49	GO:0001960	negative regulation of cytokine-mediated signaling pathway
0.46	GO:0010629	negative regulation of gene expression
0.38	GO:0045087	innate immune response
0.37	GO:1903507	negative regulation of nucleic acid-templated transcription

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.47	GO:0019899	enzyme binding
0.43	GO:0070403	NAD+ binding
0.40	GO:0003676	nucleic acid binding
0.39	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.35	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.46	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0003950

sp|Q494R0|FBAS1_HUMAN
Putative uncharacterized protein FBXL19-AS1
Search

sp|Q494R4|CC153_HUMAN
Coiled-coil domain-containing protein 153
Search

CCDC153

0.97	Coiled-coil domain-containing protein 153

0.56

GO:0005515

protein binding

sp|Q494U1|PKHN1_HUMAN
Pleckstrin homology domain-containing family N member 1
Search

PLEKHN1

0.97	Pleckstrin like proteiny domain-containing family N member 1

0.63

GO:0005515

protein binding

0.53

GO:0005886

plasma membrane

sp|Q494V2|CP100_HUMAN
Cilia- and flagella-associated protein 100
Search

CFAP100

0.91	Coiled-coil domain-containing protein 37

0.73	GO:0036159	inner dynein arm assembly
0.71	GO:2000574	regulation of microtubule motor activity
0.70	GO:0003341	cilium movement
0.39	GO:0070932	histone H3 deacetylation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:0010468	regulation of gene expression

0.70	GO:0070840	dynein complex binding
0.39	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)

0.80	GO:0097545	axonemal outer doublet
0.76	GO:0031514	motile cilium
0.36	GO:0005634	nucleus

0.39

GO:0032041

sp|Q494W8|CRFM7_HUMAN
CHRNA7-FAM7A fusion protein
Search

CHRNA7

0.90	LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-7

0.75	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0035094	response to nicotine
0.49	GO:1905920	positive regulation of CoA-transferase activity
0.49	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
0.49	GO:0050893	sensory processing
0.48	GO:0060112	generation of ovulation cycle rhythm
0.48	GO:0032720	negative regulation of tumor necrosis factor production
0.48	GO:0140059	dendrite arborization
0.48	GO:1905906	regulation of amyloid fibril formation

0.78	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.42	GO:0017081	chloride channel regulator activity
0.42	GO:0042166	acetylcholine binding
0.41	GO:0001540	amyloid-beta binding
0.41	GO:0015643	toxic substance binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0008179	adenylate cyclase binding
0.35	GO:0097110	scaffold protein binding
0.35	GO:0051117	ATPase binding

0.74	GO:0045211	postsynaptic membrane
0.70	GO:0030054	cell junction
0.54	GO:0030424	axon
0.53	GO:0043204	perikaryon
0.52	GO:0120038	plasma membrane bounded cell projection part
0.51	GO:0097447	dendritic tree
0.45	GO:0031256	leading edge membrane
0.45	GO:0005892	acetylcholine-gated channel complex
0.44	GO:0009897	external side of plasma membrane
0.44	GO:0016324	apical plasma membrane

sp|Q494X1|F153C_HUMAN
Protein FAM153C
Search

sp|Q494X3|ZN404_HUMAN
Zinc finger protein 404
Search

0.66	Zinc finger protein 84

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:0008283	cell proliferation
0.34	GO:0030154	cell differentiation

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.39	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding
0.34	GO:0016746	transferase activity, transferring acyl groups

0.44	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

GO:0016746

sp|Q495A1|TIGIT_HUMAN
T-cell immunoreceptor with Ig and ITIM domains
Search

sp|Q495B1|AKD1A_HUMAN
Ankyrin repeat and death domain-containing protein 1A
Search

ANKDD1A

0.96	Ankyrin repeat and death domain-containing protein 1A

0.60

GO:0007165

signal transduction

sp|Q495C1|RN212_HUMAN
Probable E3 SUMO-protein ligase RNF212
Search

RNF212

0.97	Ring finger protein 212

0.86	GO:0006311	meiotic gene conversion
0.85	GO:0051026	chiasma assembly
0.67	GO:0016925	protein sumoylation

0.69

GO:0019789

SUMO transferase activity

0.85

GO:0000795

synaptonemal complex

sp|Q495D7|CL036_HUMAN
Putative uncharacterized protein encoded by LINC01559
Search

sp|Q495M3|S36A2_HUMAN
Proton-coupled amino acid transporter 2
Search

0.64	Proton-coupled amino acid transporter 2

0.67	GO:0015808	L-alanine transport
0.65	GO:0015816	glycine transport
0.61	GO:0035524	proline transmembrane transport
0.50	GO:1902600	hydrogen ion transmembrane transport
0.36	GO:1900923	regulation of glycine import
0.36	GO:0070881	regulation of proline transport
0.35	GO:0051957	positive regulation of amino acid transport
0.35	GO:0051590	positive regulation of neurotransmitter transport
0.35	GO:0010155	regulation of proton transport
0.35	GO:2001025	positive regulation of response to drug

0.67	GO:0015180	L-alanine transmembrane transporter activity
0.65	GO:0015187	glycine transmembrane transporter activity
0.64	GO:0005280	amino acid:proton symporter activity
0.61	GO:0015193	L-proline transmembrane transporter activity
0.40	GO:0005302	L-tyrosine transmembrane transporter activity

0.48	GO:0005774	vacuolar membrane
0.46	GO:0005783	endoplasmic reticulum
0.42	GO:0005886	plasma membrane
0.38	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q495M9|USH1G_HUMAN
Usher syndrome type-1G protein
Search

USH1G

0.94	USH1 protein network component sans

0.86	GO:0050957	equilibrioception
0.85	GO:0045494	photoreceptor cell maintenance
0.84	GO:0060122	inner ear receptor cell stereocilium organization
0.82	GO:0042472	inner ear morphogenesis
0.82	GO:0007605	sensory perception of sound
0.78	GO:0050953	sensory perception of light stimulus

0.84	GO:0030507	spectrin binding
0.73	GO:0042803	protein homodimerization activity

0.84	GO:0001917	photoreceptor inner segment
0.84	GO:0032391	photoreceptor connecting cilium
0.81	GO:0036064	ciliary basal body
0.72	GO:0015629	actin cytoskeleton
0.48	GO:0005737	cytoplasm

sp|Q495N2|S36A3_HUMAN
Proton-coupled amino acid transporter 3
Search

SLC36A1

0.65	Proton-coupled amino acid transporter 3

0.67	GO:0015808	L-alanine transport
0.63	GO:0015816	glycine transport
0.61	GO:0035524	proline transmembrane transport
0.49	GO:1902600	hydrogen ion transmembrane transport
0.41	GO:0015827	tryptophan transport
0.36	GO:1900923	regulation of glycine import
0.35	GO:0070881	regulation of proline transport
0.35	GO:0051957	positive regulation of amino acid transport
0.35	GO:0051590	positive regulation of neurotransmitter transport
0.35	GO:0010155	regulation of proton transport

0.67	GO:0015180	L-alanine transmembrane transporter activity
0.63	GO:0015187	glycine transmembrane transporter activity
0.63	GO:0005280	amino acid:proton symporter activity
0.61	GO:0015193	L-proline transmembrane transporter activity
0.42	GO:0015173	aromatic amino acid transmembrane transporter activity

0.49	GO:0005774	vacuolar membrane
0.46	GO:0005783	endoplasmic reticulum
0.40	GO:0005886	plasma membrane
0.38	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q495T6|MMEL1_HUMAN
Membrane metallo-endopeptidase-like 1
Search

MMEL1

0.94	Membrane metalloendopeptidase like 1

0.61	GO:0006508	proteolysis
0.45	GO:0071492	cellular response to UV-A
0.45	GO:0071493	cellular response to UV-B
0.45	GO:0046449	creatinine metabolic process
0.45	GO:0090399	replicative senescence
0.44	GO:0050435	amyloid-beta metabolic process
0.43	GO:0019233	sensory perception of pain
0.43	GO:0001822	kidney development
0.42	GO:0071345	cellular response to cytokine stimulus
0.36	GO:0097242	amyloid-beta clearance

0.70	GO:0004222	metalloendopeptidase activity
0.39	GO:0008238	exopeptidase activity
0.39	GO:0008270	zinc ion binding
0.38	GO:0042277	peptide binding

0.43	GO:0005903	brush border
0.43	GO:0044306	neuron projection terminus
0.42	GO:0008021	synaptic vesicle
0.42	GO:0030425	dendrite
0.42	GO:0030424	axon
0.36	GO:0005886	plasma membrane
0.36	GO:0005576	extracellular region
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0005925	focal adhesion

0.70

GO:0004222

sp|Q495W5|FUT11_HUMAN
Alpha-(1,3)-fucosyltransferase 11
Search

FUT11

0.78	Fucosyltransferase 11

0.81	GO:0036065	fucosylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0006886	intracellular protein transport
0.34	GO:0035459	cargo loading into vesicle
0.34	GO:0051668	localization within membrane
0.33	GO:0048194	Golgi vesicle budding

0.81	GO:0008417	fucosyltransferase activity
0.34	GO:0005515	protein binding
0.34	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.80	GO:0032580	Golgi cisterna membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0030127	COPII vesicle coat
0.33	GO:0005829	cytosol
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.81

GO:0008417

sp|Q495X7|TRI60_HUMAN
Tripartite motif-containing protein 60
Search

0.93	Tripartite motif-containing protein 60

0.39	GO:0007275	multicellular organism development
0.36	GO:0016567	protein ubiquitination
0.36	GO:0060765	regulation of androgen receptor signaling pathway
0.36	GO:0071641	negative regulation of macrophage inflammatory protein 1 alpha production
0.36	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly
0.35	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.35	GO:0032691	negative regulation of interleukin-1 beta production
0.35	GO:0032695	negative regulation of interleukin-12 production
0.35	GO:0034341	response to interferon-gamma
0.35	GO:2001056	positive regulation of cysteine-type endopeptidase activity

0.59	GO:0008270	zinc ion binding
0.37	GO:0016874	ligase activity
0.36	GO:0050681	androgen receptor binding
0.36	GO:0035035	histone acetyltransferase binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0042802	identical protein binding
0.34	GO:0003779	actin binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.43	GO:0005622	intracellular
0.34	GO:0005615	extracellular space
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0012505	endomembrane system
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.37	EC:6	GO:0016874
0.35	KEGG:R03876	GO:0004842

sp|Q495Y7|SPDE7_HUMAN
Putative speedy protein E7
Search

0.86	Speedy protein B

0.72	GO:0045859	regulation of protein kinase activity
0.65	GO:0008315	G2/MI transition of meiotic cell cycle
0.61	GO:0001556	oocyte maturation
0.60	GO:0051446	positive regulation of meiotic cell cycle
0.56	GO:0006378	mRNA polyadenylation
0.56	GO:0043410	positive regulation of MAPK cascade
0.55	GO:0033674	positive regulation of kinase activity
0.51	GO:0007275	multicellular organism development

0.77	GO:0019901	protein kinase binding
0.57	GO:0030332	cyclin binding

0.49	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q495Y8|SPDE2_HUMAN
Speedy protein E2
Search

0.85	Speedy protein E4

0.68	GO:0045859	regulation of protein kinase activity
0.67	GO:0008315	G2/MI transition of meiotic cell cycle
0.62	GO:0001556	oocyte maturation
0.61	GO:0051446	positive regulation of meiotic cell cycle
0.58	GO:0006378	mRNA polyadenylation
0.57	GO:0043410	positive regulation of MAPK cascade
0.56	GO:0033674	positive regulation of kinase activity
0.52	GO:0007275	multicellular organism development

0.73	GO:0019901	protein kinase binding
0.58	GO:0030332	cyclin binding

0.50	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q495Z4|ASAS1_HUMAN
Putative uncharacterized protein ASB16-AS1
Search

sp|Q496A3|SPAS1_HUMAN
Spermatogenesis-associated serine-rich protein 1
Search

SPATS1

0.97	Spermatogenesis associated serine rich 1

sp|Q496F6|CLM2_HUMAN
CMRF35-like molecule 2
Search

0.95	Polymeric immunoglobulin receptor 4

0.45	GO:0034125	negative regulation of MyD88-dependent toll-like receptor signaling pathway
0.45	GO:0051134	negative regulation of NK T cell activation
0.45	GO:1902569	negative regulation of activation of Janus kinase activity
0.45	GO:1902567	negative regulation of eosinophil activation
0.44	GO:2000417	negative regulation of eosinophil migration
0.44	GO:0060101	negative regulation of phagocytosis, engulfment
0.44	GO:1902564	negative regulation of neutrophil activation
0.44	GO:0033004	negative regulation of mast cell activation
0.44	GO:0050859	negative regulation of B cell receptor signaling pathway
0.44	GO:0002887	negative regulation of myeloid leukocyte mediated immunity

0.43	GO:0001786	phosphatidylserine binding
0.43	GO:0008429	phosphatidylethanolamine binding
0.38	GO:0038023	signaling receptor activity
0.37	GO:0001618	virus receptor activity
0.36	GO:0005515	protein binding
0.35	GO:0097001	ceramide binding
0.34	GO:0099600	transmembrane receptor activity

0.41	GO:0070062	extracellular exosome
0.38	GO:0005886	plasma membrane
0.35	GO:0005764	lysosome
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0005581	collagen trimer
0.34	GO:0005769	early endosome
0.30	GO:0016021	integral component of membrane

sp|Q496H8|NRN1L_HUMAN
Neuritin-like protein
Search

NRN1L

0.97	Neuritin 1 like

0.74	GO:0007399	nervous system development
0.61	GO:0048588	developmental cell growth
0.60	GO:0060560	developmental growth involved in morphogenesis
0.58	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.57	GO:0120036	plasma membrane bounded cell projection organization
0.40	GO:0006501	C-terminal protein lipidation
0.39	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.33	GO:0006468	protein phosphorylation

0.56	GO:0042803	protein homodimerization activity
0.55	GO:0046982	protein heterodimerization activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0046658	anchored component of plasma membrane
0.59	GO:0030424	axon
0.55	GO:0005615	extracellular space
0.43	GO:0000932	P-body
0.40	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|Q496J9|SV2C_HUMAN
Synaptic vesicle glycoprotein 2C
Search

SV2C

0.94	Synaptic vesicle glycoprotein 2C

0.76	GO:0007268	chemical synaptic transmission
0.54	GO:0055085	transmembrane transport
0.44	GO:0006874	cellular calcium ion homeostasis
0.38	GO:0006836	neurotransmitter transport
0.35	GO:0014052	regulation of gamma-aminobutyric acid secretion

0.56	GO:0022857	transmembrane transporter activity
0.43	GO:0019901	protein kinase binding
0.39	GO:0004872	receptor activity

0.56	GO:0008021	synaptic vesicle
0.45	GO:0031594	neuromuscular junction
0.44	GO:0048786	presynaptic active zone
0.44	GO:0030054	cell junction
0.43	GO:0043005	neuron projection
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0099501	exocytic vesicle membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0031301	integral component of organelle membrane
0.33	GO:0120038	plasma membrane bounded cell projection part

sp|Q496M5|PLK5_HUMAN
Inactive serine/threonine-protein kinase PLK5
Search

PLK5

0.96	Inactive serine/threonine-protein kinase PLK5

0.63	GO:0006468	protein phosphorylation
0.52	GO:0002357	defense response to tumor cell
0.48	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.48	GO:0010976	positive regulation of neuron projection development
0.47	GO:0071363	cellular response to growth factor stimulus
0.45	GO:0042981	regulation of apoptotic process
0.39	GO:0008285	negative regulation of cell proliferation
0.38	GO:0051301	cell division
0.38	GO:0007049	cell cycle
0.36	GO:0006974	cellular response to DNA damage stimulus

0.63	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.32	GO:0004721	phosphoprotein phosphatase activity

0.41	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004721

sp|Q496Y0|LONF3_HUMAN
LON peptidase N-terminal domain and RING finger protein 3
Search

LONRF3

0.93	LON peptidase N-terminal domain and RING finger protein 3

0.64	GO:0016567	protein ubiquitination
0.59	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process

0.65	GO:0004842	ubiquitin-protein transferase activity
0.60	GO:0031624	ubiquitin conjugating enzyme binding
0.54	GO:0061659	ubiquitin-like protein ligase activity
0.46	GO:0046872	metal ion binding

0.38

GO:0005622

intracellular

0.65

GO:0004842

sp|Q499Y3|YJ016_HUMAN
Putative uncharacterized protein C10orf88-like
Search

sp|Q499Z3|SLNL1_HUMAN
Schlafen-like protein 1
Search

SLFNL1

0.97	Schlafen like 1

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.35	GO:0003723	RNA binding

sp|Q499Z4|ZN672_HUMAN
Zinc finger protein 672
Search

ZNF672

0.43	myeloid zinc finger 1

0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.44	GO:0006366	transcription by RNA polymerase II
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:1990823	response to leukemia inhibitory factor
0.33	GO:0071345	cellular response to cytokine stimulus
0.33	GO:1904668	positive regulation of ubiquitin protein ligase activity

0.51	GO:0003676	nucleic acid binding
0.46	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0042803	protein homodimerization activity
0.42	GO:0046872	metal ion binding
0.33	GO:0097027	ubiquitin-protein transferase activator activity
0.33	GO:0010997	anaphase-promoting complex binding

0.48	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q49A17|GLTL6_HUMAN
Polypeptide N-acetylgalactosaminyltransferase-like 6
Search

GALNT10

0.65	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0043413	macromolecule glycosylation
0.72	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0006464	cellular protein modification process

0.68	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.45	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0046872	metal ion binding

0.72	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

sp|Q49A26|GLYR1_HUMAN
Putative oxidoreductase GLYR1
Search

GLYR1

0.96	Glyoxylate reductase 1 homolog

0.53

GO:0055114

oxidation-reduction process

0.76	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.68	GO:0051287	NAD binding
0.66	GO:0140034	methylation-dependent protein binding
0.63	GO:0042393	histone binding

0.63	GO:0016607	nuclear speck
0.60	GO:0000786	nucleosome
0.58	GO:0005794	Golgi apparatus
0.56	GO:0005829	cytosol

0.76

EC:1.1.1.44

GO:0004616

sp|Q49A33|Z876P_HUMAN
Putative zinc finger protein 876
Search

0.61	Zinc finger protein 383

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:0070895	negative regulation of transposon integration
0.37	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle

sp|Q49A88|CCD14_HUMAN
Coiled-coil domain-containing protein 14
Search

CCDC14

0.97	Coiled-coil domain-containing protein 14

0.85	GO:0071539	protein localization to centrosome
0.51	GO:0021762	substantia nigra development

0.39

GO:0005515

protein binding

0.85	GO:0034451	centriolar satellite
0.30	GO:0031224	intrinsic component of membrane

sp|Q49A92|CH034_HUMAN
Uncharacterized protein C8orf34
Search

0.56	GO:0035023	regulation of Rho protein signal transduction
0.50	GO:0065009	regulation of molecular function
0.48	GO:0035556	intracellular signal transduction

0.63

GO:0030676

Rac guanyl-nucleotide exchange factor activity

0.38	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q49AA0|ZFP69_HUMAN
Zinc finger protein ZFP69
Search

0.87	Zinc finger imprinted 3

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.46	GO:0006351	transcription, DNA-templated
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:1902680	positive regulation of RNA biosynthetic process
0.33	GO:0007219	Notch signaling pathway
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0006259	DNA metabolic process
0.32	GO:0032259	methylation

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.49	GO:0003700	DNA binding transcription factor activity
0.34	GO:0045145	single-stranded DNA 5'-3' exodeoxyribonuclease activity
0.34	GO:0005515	protein binding
0.33	GO:0003682	chromatin binding
0.32	GO:0008168	methyltransferase activity

0.49	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.32

GO:0008168

sp|Q49AG3|ZBED5_HUMAN
Zinc finger BED domain-containing protein 5
Search

ZBED5

0.25	Zinc finger BED domain-containing protein 5

0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0015074	DNA integration
0.37	GO:0007010	cytoskeleton organization
0.37	GO:0022604	regulation of cell morphogenesis
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0007275	multicellular organism development

0.52	GO:0003677	DNA binding
0.50	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.42	GO:0046983	protein dimerization activity
0.38	GO:0004531	deoxyribonuclease II activity
0.38	GO:0046872	metal ion binding

0.49	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.34	GO:0005681	spliceosomal complex

0.38

EC:3.1.22.1

GO:0004531

sp|Q49AH0|CDNF_HUMAN
Cerebral dopamine neurotrophic factor
Search

0.96	Mesencephalic astrocyte derived neurotrophic factor

0.83	GO:0071542	dopaminergic neuron differentiation
0.69	GO:0031175	neuron projection development
0.48	GO:0010469	regulation of receptor activity
0.44	GO:0006986	response to unfolded protein
0.44	GO:0002014	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure
0.38	GO:0002576	platelet degranulation
0.36	GO:0007264	small GTPase mediated signal transduction
0.34	GO:0006886	intracellular protein transport

0.49	GO:0008083	growth factor activity
0.38	GO:0003723	RNA binding
0.36	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0005509	calcium ion binding

0.66	GO:0005615	extracellular space
0.64	GO:0005783	endoplasmic reticulum
0.42	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q49AJ0|F135B_HUMAN
Protein FAM135B
Search

sp|Q49AM1|MTEF2_HUMAN
Transcription termination factor 2, mitochondrial
Search

MTERF2

0.88	Mitochondrial transcription termination factor 2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006393	termination of mitochondrial transcription

0.72

GO:0003690

double-stranded DNA binding

0.60

GO:0042645

mitochondrial nucleoid

sp|Q49AM3|TTC31_HUMAN
Tetratricopeptide repeat protein 31
Search

TTC31

0.95	Tetratricopeptide repeat protein 31

0.44

GO:0000226

microtubule cytoskeleton organization

0.57	GO:0003723	RNA binding
0.39	GO:0046872	metal ion binding

0.42

GO:0015630

microtubule cytoskeleton

sp|Q49AN0|CRY2_HUMAN
Cryptochrome-2
Search

CRY2

0.88	Cryptochrome circadian clock 2

0.79	GO:2000850	negative regulation of glucocorticoid secretion
0.79	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.77	GO:0042754	negative regulation of circadian rhythm
0.77	GO:0043153	entrainment of circadian clock by photoperiod
0.74	GO:0032922	circadian regulation of gene expression
0.71	GO:0032868	response to insulin
0.71	GO:0019915	lipid storage
0.70	GO:0042593	glucose homeostasis
0.67	GO:0045892	negative regulation of transcription, DNA-templated
0.67	GO:0006606	protein import into nucleus

0.71	GO:0035257	nuclear hormone receptor binding
0.67	GO:0019901	protein kinase binding
0.66	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.63	GO:0071949	FAD binding
0.46	GO:0019902	phosphatase binding
0.45	GO:0009881	photoreceptor activity
0.44	GO:0000989	transcription factor activity, transcription factor binding
0.43	GO:0016829	lyase activity
0.42	GO:0001047	core promoter binding
0.41	GO:0042826	histone deacetylase binding

0.67	GO:0016607	nuclear speck
0.60	GO:0005829	cytosol
0.53	GO:0005739	mitochondrion
0.46	GO:0005667	transcription factor complex
0.45	GO:0097381	photoreceptor disc membrane
0.44	GO:0042622	photoreceptor outer segment membrane
0.37	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.43

EC:4

GO:0016829

sp|Q49AR2|CE022_HUMAN
UPF0489 protein C5orf22
Search

0.50

GO:0046580

negative regulation of Ras protein signal transduction

0.50	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.30

GO:0031224

intrinsic component of membrane

sp|Q49AS3|L37A5_HUMAN
Putative protein LRRC37A5P
Search

sp|Q49B96|COX19_HUMAN
Cytochrome c oxidase assembly protein COX19
Search

COX19

0.91	Mitochondrial cytochrome c oxidase assembly protein COX19

0.69	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.67	GO:0006878	cellular copper ion homeostasis
0.53	GO:0009060	aerobic respiration
0.39	GO:0043547	positive regulation of GTPase activity
0.38	GO:0030001	metal ion transport

0.40	GO:1902936	phosphatidylinositol bisphosphate binding
0.39	GO:0005507	copper ion binding
0.39	GO:0005096	GTPase activator activity
0.38	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.36	GO:0005515	protein binding
0.36	GO:0004633	phosphopantothenoylcysteine decarboxylase activity
0.33	GO:0003676	nucleic acid binding

0.75	GO:0005758	mitochondrial intermembrane space
0.59	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:1.6.5.3	GO:0008137
0.36	KEGG:R03269	GO:0004633

sp|Q49MG5|MAP9_HUMAN
Microtubule-associated protein 9
Search

MAP9

0.96	Microtubule-associated protein 9

0.82	GO:0051225	spindle assembly
0.79	GO:0007088	regulation of mitotic nuclear division
0.72	GO:0000910	cytokinesis
0.59	GO:0060236	regulation of mitotic spindle organization
0.59	GO:0046605	regulation of centrosome cycle
0.58	GO:0007052	mitotic spindle organization
0.57	GO:1902412	regulation of mitotic cytokinesis
0.56	GO:0140014	mitotic nuclear division
0.37	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.32	GO:0001123	transcription initiation from bacterial-type RNA polymerase promoter

0.54	GO:0008017	microtubule binding
0.32	GO:0051287	NAD binding
0.32	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.31	GO:0000996	promoter selection factor activity
0.31	GO:0003700	DNA binding transcription factor activity
0.31	GO:0003677	DNA binding

0.61	GO:0000235	astral microtubule
0.59	GO:0051233	spindle midzone
0.58	GO:0072686	mitotic spindle
0.35	GO:0005813	centrosome

0.32

EC:1.1.1

GO:0016616

sp|Q49MI3|CERKL_HUMAN
Ceramide kinase-like protein
Search

CERKL

0.89	Ceramide kinase like

0.61	GO:0030148	sphingolipid biosynthetic process
0.57	GO:0016310	phosphorylation
0.51	GO:0043066	negative regulation of apoptotic process
0.47	GO:2000425	regulation of apoptotic cell clearance
0.46	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.46	GO:0010842	retina layer formation
0.46	GO:1903202	negative regulation of oxidative stress-induced cell death
0.45	GO:0042461	photoreceptor cell development
0.43	GO:1902532	negative regulation of intracellular signal transduction

0.73	GO:0003951	NAD+ kinase activity
0.65	GO:0046625	sphingolipid binding
0.51	GO:0001729	ceramide kinase activity

0.63	GO:0001917	photoreceptor inner segment
0.62	GO:0001750	photoreceptor outer segment
0.58	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005829	cytosol
0.50	GO:0005634	nucleus
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part

0.73	EC:2.7.1.23	GO:0003951
0.73	KEGG:R00104	GO:0003951

sp|Q49SQ1|GPR33_HUMAN
Probable G-protein coupled receptor 33
Search

GPR33

0.80	G protein-coupled receptor 33 variant 1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0002430	complement receptor mediated signaling pathway
0.52	GO:0050900	leukocyte migration
0.52	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.51	GO:0060326	cell chemotaxis
0.51	GO:0006954	inflammatory response
0.36	GO:0006629	lipid metabolic process
0.35	GO:0002283	neutrophil activation involved in immune response

0.72	GO:0004930	G-protein coupled receptor activity
0.56	GO:0004875	complement receptor activity
0.35	GO:0001847	opsonin receptor activity
0.35	GO:0001653	peptide receptor activity

0.45

GO:0005887

integral component of plasma membrane

sp|Q4AC94|C2CD3_HUMAN
C2 domain-containing protein 3
Search

C2CD3

0.94	LOW QUALITY PROTEIN: C2 domain-containing protein 3

0.87	GO:0061511	centriole elongation
0.87	GO:0021997	neural plate axis specification
0.85	GO:0071539	protein localization to centrosome
0.85	GO:0042733	embryonic digit morphogenesis
0.85	GO:0001947	heart looping
0.84	GO:0008589	regulation of smoothened signaling pathway
0.84	GO:1905515	non-motile cilium assembly
0.83	GO:0021915	neural tube development
0.80	GO:0001701	in utero embryonic development
0.79	GO:0007420	brain development

0.39

GO:0005515

protein binding

0.85	GO:0034451	centriolar satellite
0.82	GO:0005814	centriole
0.82	GO:0036064	ciliary basal body
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q4AC99|1A1L2_HUMAN
Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2
Search

ACCS

0.95	1-aminocyclopropane-1-carboxylate synthase homolog

0.49	GO:0009058	biosynthetic process
0.35	GO:0043413	macromolecule glycosylation
0.35	GO:0009100	glycoprotein metabolic process
0.35	GO:0072662	protein localization to peroxisome
0.35	GO:0043574	peroxisomal transport
0.34	GO:0072594	establishment of protein localization to organelle
0.34	GO:0036211	protein modification process
0.34	GO:0006605	protein targeting
0.33	GO:0044267	cellular protein metabolic process

0.67	GO:0030170	pyridoxal phosphate binding
0.45	GO:0042802	identical protein binding
0.39	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity
0.34	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0042623	ATPase activity, coupled
0.33	GO:0046983	protein dimerization activity
0.32	GO:0005524	ATP binding

0.34	GO:0031903	microbody membrane
0.34	GO:0044439	peroxisomal part
0.30	GO:0016021	integral component of membrane

0.39	EC:4.4.1.14	GO:0016847
0.39	KEGG:R00179	GO:0016847

sp|Q4ADV7|RIC1_HUMAN
RAB6A-GEF complex partner protein 1
Search

RIC1

0.97	RAB6A GEF complex partner 1

0.84	GO:1903363	negative regulation of cellular protein catabolic process
0.81	GO:0042147	retrograde transport, endosome to Golgi
0.75	GO:0043547	positive regulation of GTPase activity
0.53	GO:0006886	intracellular protein transport

0.85

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.86	GO:0034066	RIC1-RGP1 guanyl-nucleotide exchange factor complex
0.69	GO:0005829	cytosol
0.56	GO:0000139	Golgi membrane

sp|Q4AE62|GTDC1_HUMAN
Glycosyltransferase-like domain-containing protein 1
Search

GTDC1

0.94	Glycosyltransferase like domain containing 1

0.44

GO:0007417

central nervous system development

0.50

GO:0016740

transferase activity

0.50

GO:0016740

sp|Q4FZB7|KMT5B_HUMAN
Histone-lysine N-methyltransferase KMT5B
Search

KMT5B

0.51	Histone-lysine N-methyltransferase

0.85	GO:0034773	histone H4-K20 trimethylation
0.41	GO:0007517	muscle organ development
0.40	GO:0040014	regulation of multicellular organism growth
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.85	GO:0042799	histone methyltransferase activity (H4-K20 specific)
0.34	GO:0005515	protein binding

0.55	GO:0000780	condensed nuclear chromosome, centromeric region
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q4G0A6|MINY4_HUMAN
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4
Search

MINDY4

0.97	Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

0.51	GO:0006508	proteolysis
0.46	GO:0055085	transmembrane transport
0.44	GO:0006833	water transport
0.42	GO:0015670	carbon dioxide transport
0.41	GO:0072220	metanephric descending thin limb development
0.41	GO:0072032	proximal convoluted tubule segment 2 development
0.41	GO:0072230	metanephric proximal straight tubule development
0.41	GO:0072229	metanephric proximal convoluted tubule development
0.41	GO:0085018	maintenance of symbiont-containing vacuole by host
0.41	GO:0051458	corticotropin secretion

0.62	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.56	GO:0022803	passive transmembrane transporter activity
0.44	GO:0005372	water transmembrane transporter activity
0.42	GO:0035379	carbon dioxide transmembrane transporter activity
0.40	GO:0046875	ephrin receptor binding
0.39	GO:0008519	ammonium transmembrane transporter activity
0.38	GO:0015079	potassium ion transmembrane transporter activity
0.37	GO:0008061	chitin binding
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.43	GO:0016323	basolateral plasma membrane
0.41	GO:0020003	symbiont-containing vacuole
0.40	GO:0045178	basal part of cell
0.39	GO:0005903	brush border
0.39	GO:0005901	caveola
0.39	GO:0016324	apical plasma membrane
0.39	GO:0070062	extracellular exosome
0.39	GO:0030424	axon
0.37	GO:0005887	integral component of plasma membrane

0.62

GO:0036459

sp|Q4G0F5|VP26B_HUMAN
Vacuolar protein sorting-associated protein 26B
Search

VPS26B

0.94	Vacuolar protein sorting-associated protein 26B-A

0.61	GO:0007165	signal transduction
0.55	GO:0042147	retrograde transport, endosome to Golgi
0.54	GO:0071346	cellular response to interferon-gamma
0.43	GO:0006886	intracellular protein transport
0.35	GO:0016241	regulation of macroautophagy

0.43	GO:0008565	protein transporter activity
0.33	GO:0005515	protein binding

0.55	GO:0030904	retromer complex
0.54	GO:0045335	phagocytic vesicle
0.53	GO:0005768	endosome
0.49	GO:0005829	cytosol
0.34	GO:0044433	cytoplasmic vesicle part
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

sp|Q4G0G2|H1AS1_HUMAN
Putative uncharacterized protein H1FX-AS1
Search

sp|Q4G0G5|SC2B2_HUMAN
Secretoglobin family 2B member 2
Search

SCGB2B2

0.97	Secretoglobin family 2B member 2

0.66

GO:0005576

extracellular region

sp|Q4G0I0|CSMT1_HUMAN
Protein CCSMST1
Search

0.30

GO:0044425

membrane part

sp|Q4G0J3|LARP7_HUMAN
La-related protein 7
Search

LARP7

0.94	La ribonucleoprotein domain family member 7

0.61	GO:0006396	RNA processing
0.38	GO:0036093	germ cell proliferation
0.38	GO:0035562	negative regulation of chromatin binding
0.38	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.36	GO:0000122	negative regulation of transcription by RNA polymerase II
0.32	GO:0061026	cardiac muscle tissue regeneration
0.32	GO:0060043	regulation of cardiac muscle cell proliferation
0.31	GO:0006468	protein phosphorylation
0.31	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0004519	endonuclease activity
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0046872	metal ion binding

0.60	GO:0005634	nucleus
0.60	GO:0030529	intracellular ribonucleoprotein complex
0.49	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.40	GO:0019013	viral nucleocapsid
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004674

sp|Q4G0M1|ERFE_HUMAN
Erythroferrone
Search

ERFE

0.97	Erythroferrone

0.79	GO:2000193	positive regulation of fatty acid transport
0.72	GO:0019217	regulation of fatty acid metabolic process
0.67	GO:0006879	cellular iron ion homeostasis
0.66	GO:0010469	regulation of receptor activity
0.38	GO:0048856	anatomical structure development
0.37	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.37	GO:0006955	immune response
0.36	GO:0021700	developmental maturation
0.36	GO:0007155	cell adhesion
0.35	GO:0032528	microvillus organization

0.69	GO:0005179	hormone activity
0.66	GO:0042803	protein homodimerization activity
0.52	GO:0042302	structural constituent of cuticle
0.38	GO:0005164	tumor necrosis factor receptor binding
0.35	GO:0005201	extracellular matrix structural constituent
0.35	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.34	GO:0030246	carbohydrate binding

0.65	GO:0005615	extracellular space
0.51	GO:0005581	collagen trimer
0.36	GO:0031012	extracellular matrix
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q4G0N0|GGTA1_HUMAN
Inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase
Search

0.92	Inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase

0.62	GO:0033580	protein galactosylation at cell surface
0.60	GO:0005975	carbohydrate metabolic process
0.45	GO:0030259	lipid glycosylation
0.44	GO:0009247	glycolipid biosynthetic process
0.42	GO:1901748	leukotriene D4 metabolic process
0.41	GO:0019370	leukotriene biosynthetic process
0.37	GO:0044272	sulfur compound biosynthetic process
0.36	GO:0043043	peptide biosynthetic process

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.49	GO:0008194	UDP-glycosyltransferase activity
0.40	GO:0046872	metal ion binding

0.54	GO:0031985	Golgi cisterna
0.50	GO:0000139	Golgi membrane
0.44	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016758

sp|Q4G0N4|NAKD2_HUMAN
NAD kinase 2, mitochondrial
Search

NADK2

0.93	NAD kinase 2, mitochondrial

0.73	GO:0006741	NADP biosynthetic process
0.67	GO:0019674	NAD metabolic process
0.55	GO:0016310	phosphorylation

0.71	GO:0003951	NAD+ kinase activity
0.67	GO:0042803	protein homodimerization activity
0.50	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.71	EC:2.7.1.23	GO:0003951
0.71	KEGG:R00104	GO:0003951

sp|Q4G0N7|F229B_HUMAN
Protein FAM229B
Search

sp|Q4G0N8|SL9C1_HUMAN
Sodium/hydrogen exchanger 10
Search

SLC9C1

0.97	Solute carrier family 9 member C1

0.85	GO:0030317	flagellated sperm motility
0.63	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0098719	sodium ion import across plasma membrane
0.57	GO:0051453	regulation of intracellular pH
0.52	GO:0071804	cellular potassium ion transport

0.74	GO:0015299	solute:proton antiporter activity
0.57	GO:0022821	potassium ion antiporter activity
0.54	GO:0015491	cation:cation antiporter activity
0.53	GO:0005216	ion channel activity
0.52	GO:0015081	sodium ion transmembrane transporter activity

0.72	GO:0031514	motile cilium
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q4G0P3|HYDIN_HUMAN
Hydrocephalus-inducing protein homolog
Search

HYDIN

0.88	LOW QUALITY PROTEIN: hydrocephalus-inducing protein homolog

0.87	GO:1904158	axonemal central apparatus assembly
0.85	GO:0060438	trachea development
0.85	GO:0021591	ventricular system development
0.83	GO:0003341	cilium movement
0.81	GO:0002064	epithelial cell development
0.37	GO:0010469	regulation of receptor activity
0.34	GO:0032259	methylation

0.37	GO:0005179	hormone activity
0.37	GO:0030976	thiamine pyrophosphate binding
0.36	GO:0000287	magnesium ion binding
0.34	GO:0008168	methyltransferase activity

0.88	GO:1990718	axonemal central pair projection
0.36	GO:0005576	extracellular region

0.34

GO:0008168

sp|Q4G0S4|C27C1_HUMAN
Cytochrome P450 27C1
Search

CYP27C1

0.97	Excision repair cross-complementation group 3

0.55	GO:0042574	retinal metabolic process
0.55	GO:0042573	retinoic acid metabolic process
0.54	GO:0042572	retinol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0036378	calcitriol biosynthetic process from calciol
0.40	GO:0071425	hematopoietic stem cell proliferation
0.38	GO:0070564	positive regulation of vitamin D receptor signaling pathway
0.38	GO:0042369	vitamin D catabolic process
0.38	GO:0010979	regulation of vitamin D 24-hydroxylase activity
0.38	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.58	GO:1904768	all-trans-retinol binding
0.57	GO:0005503	all-trans retinal binding
0.56	GO:0005502	11-cis retinal binding
0.55	GO:0001972	retinoic acid binding
0.32	GO:0004003	ATP-dependent DNA helicase activity
0.31	GO:0030554	adenyl nucleotide binding

0.42	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.33	GO:0031967	organelle envelope
0.33	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q4G0S7|CC152_HUMAN
Coiled-coil domain-containing protein 152
Search

CCDC152

0.97	Coiled-coil domain-containing protein 152

sp|Q4G0T1|SRCRM_HUMAN
Scavenger receptor cysteine-rich domain-containing protein SCART1
Search

0.86	Scavenger receptor cysteine-rich domain-containing protein SCART1

0.72	GO:0006898	receptor-mediated endocytosis
0.35	GO:0002438	acute inflammatory response to antigenic stimulus
0.35	GO:0001771	immunological synapse formation
0.35	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.35	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.35	GO:0031663	lipopolysaccharide-mediated signaling pathway
0.35	GO:0042102	positive regulation of T cell proliferation
0.34	GO:0034755	iron ion transmembrane transport
0.34	GO:0006879	cellular iron ion homeostasis
0.30	GO:0002443	leukocyte mediated immunity

0.81	GO:0005044	scavenger receptor activity
0.35	GO:0070891	lipoteichoic acid binding
0.35	GO:0070287	ferritin receptor activity
0.34	GO:0001530	lipopolysaccharide binding
0.34	GO:0042802	identical protein binding
0.33	GO:0005509	calcium ion binding

0.47	GO:0005903	brush border
0.36	GO:0005737	cytoplasm
0.36	GO:0005576	extracellular region
0.35	GO:0042101	T cell receptor complex
0.35	GO:0001772	immunological synapse
0.34	GO:0031226	intrinsic component of plasma membrane
0.34	GO:0012506	vesicle membrane
0.33	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

sp|Q4G0U5|PCDP1_HUMAN
Cilia- and flagella-associated protein 221
Search

CFAP221

0.97	Primary ciliary dyskinesia protein 1

0.84	GO:0003341	cilium movement
0.79	GO:0060271	cilium assembly

0.57	GO:0005516	calmodulin binding
0.33	GO:0004040	amidase activity

0.76	GO:0005929	cilium
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.37	GO:0044430	cytoskeletal part
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.5.1.4

GO:0004040

sp|Q4G0W2|DUS28_HUMAN
Dual specificity phosphatase 28
Search

DUSP28

0.97	Dual specificity phosphatase 28

0.72	GO:0006470	protein dephosphorylation
0.70	GO:0000188	inactivation of MAPK activity
0.32	GO:0006508	proteolysis

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.70	GO:0033549	MAP kinase phosphatase activity
0.40	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0043395	heparan sulfate proteoglycan binding
0.33	GO:0070006	metalloaminopeptidase activity
0.32	GO:0008270	zinc ion binding

0.38	GO:0046658	anchored component of plasma membrane
0.37	GO:0005578	proteinaceous extracellular matrix

0.78

GO:0008138

sp|Q4G0X4|KCD21_HUMAN
BTB/POZ domain-containing protein KCTD21
Search

KCTD21

0.97	Potassium channel tetramerization domain containing 21

0.78	GO:0051260	protein homooligomerization
0.61	GO:0045879	negative regulation of smoothened signaling pathway
0.53	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0040008	regulation of growth
0.36	GO:0016567	protein ubiquitination
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0007406	negative regulation of neuroblast proliferation
0.33	GO:0045666	positive regulation of neuron differentiation
0.33	GO:0006012	galactose metabolic process
0.33	GO:0046835	carbohydrate phosphorylation

0.62	GO:0097602	cullin family protein binding
0.60	GO:0042826	histone deacetylase binding
0.54	GO:0042802	identical protein binding
0.35	GO:0003714	transcription corepressor activity
0.34	GO:0030506	ankyrin binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0004335	galactokinase activity
0.33	GO:0005534	galactose binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.33	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33	EC:2.7.1.6	GO:0004335
0.33	KEGG:R01092	GO:0004335

sp|Q4G0X9|CCD40_HUMAN
Coiled-coil domain-containing protein 40
Search

CCDC40

0.97	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 40

0.84	GO:0035082	axoneme assembly
0.70	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.67	GO:0035469	determination of pancreatic left/right asymmetry
0.66	GO:0071910	determination of liver left/right asymmetry
0.66	GO:0001947	heart looping
0.66	GO:0003356	regulation of cilium beat frequency
0.66	GO:0071907	determination of digestive tract left/right asymmetry
0.64	GO:0044458	motile cilium assembly
0.63	GO:0030317	flagellated sperm motility
0.62	GO:0030324	lung development

0.34	GO:0030246	carbohydrate binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.64	GO:0005930	axoneme
0.35	GO:0031514	motile cilium

0.34

GO:0004553

sp|Q4G0Z9|MCMD2_HUMAN
MCM domain-containing protein 2
Search

MCMDC2

0.97	MCM domain-containing protein 2

0.75	GO:0006270	DNA replication initiation
0.48	GO:0042140	late meiotic recombination nodule assembly
0.47	GO:1990918	double-strand break repair involved in meiotic recombination
0.45	GO:0007130	synaptonemal complex assembly
0.44	GO:0048477	oogenesis
0.44	GO:0007283	spermatogenesis

0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

sp|Q4G112|HSF5_HUMAN
Heat shock factor protein 5
Search

HSF5

0.97	Heat shock transcription factor 5

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.47	GO:0007179	transforming growth factor beta receptor signaling pathway
0.44	GO:0035335	peptidyl-tyrosine dephosphorylation
0.37	GO:0006351	transcription, DNA-templated
0.34	GO:0034605	cellular response to heat

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.45	GO:0004722	protein serine/threonine phosphatase activity
0.44	GO:0004725	protein tyrosine phosphatase activity
0.37	GO:0046872	metal ion binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.34	GO:0034708	methyltransferase complex
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0004725

sp|Q4G148|GXLT1_HUMAN
Glucoside xylosyltransferase 1
Search

GXYLT1

0.97	Glycosyltransferase 8 domain-containing protein 3

0.55

GO:0016266

O-glycan processing

0.65

GO:0016757

transferase activity, transferring glycosyl groups

0.30

GO:0031224

intrinsic component of membrane

0.65

GO:0016757

sp|Q4G163|FBX43_HUMAN
F-box only protein 43
Search

FBXO43

0.97	Regulator of G protein signaling 22

0.69	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.65	GO:0045835	negative regulation of meiotic nuclear division
0.60	GO:0007088	regulation of mitotic nuclear division
0.45	GO:0051321	meiotic cell cycle
0.42	GO:0016567	protein ubiquitination
0.39	GO:0042177	negative regulation of protein catabolic process
0.37	GO:0001556	oocyte maturation
0.36	GO:0051225	spindle assembly
0.36	GO:0046785	microtubule polymerization
0.36	GO:0016050	vesicle organization

0.49	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding
0.38	GO:1990948	ubiquitin ligase inhibitor activity
0.36	GO:0015002	heme-copper terminal oxidase activity
0.36	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.35	GO:0015078	hydrogen ion transmembrane transporter activity
0.35	GO:0009055	electron transfer activity

0.50	GO:0005634	nucleus
0.36	GO:0005819	spindle
0.35	GO:0031974	membrane-enclosed lumen
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

EC:1.9.3

GO:0016676

sp|Q4G176|ACSF3_HUMAN
Acyl-CoA synthetase family member 3, mitochondrial
Search

ACSF3

0.92	Acyl-CoA synthetase family member 3, mitochondrial

0.64	GO:0090410	malonate catabolic process
0.51	GO:0006633	fatty acid biosynthetic process
0.37	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.64	GO:0090409	malonyl-CoA synthetase activity
0.37	GO:0031957	very long-chain fatty acid-CoA ligase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0032553	ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005509	calcium ion binding

0.47	GO:0005739	mitochondrion
0.35	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:6.2.1

GO:0090409

sp|Q4G1C9|GRPL2_HUMAN
GLIPR1-like protein 2
Search

GLIPR1

0.97	GLI pathogenesis related 1 like 2

0.55	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q4J6C6|PPCEL_HUMAN
Prolyl endopeptidase-like
Search

PREPL

0.70	Prolyl endopeptidase

0.65	GO:2000300	regulation of synaptic vesicle exocytosis
0.60	GO:0006508	proteolysis

0.72	GO:0070008	serine-type exopeptidase activity
0.67	GO:0004252	serine-type endopeptidase activity

0.55	GO:0005794	Golgi apparatus
0.54	GO:0005856	cytoskeleton
0.40	GO:0005829	cytosol

0.72

GO:0070008

sp|Q4JDL3|PTN20_HUMAN
Tyrosine-protein phosphatase non-receptor type 20
Search

PTPN20

0.57	Tyrosine-protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0070830	bicellular tight junction assembly
0.36	GO:0071310	cellular response to organic substance
0.36	GO:0030073	insulin secretion
0.35	GO:0034097	response to cytokine
0.35	GO:0006469	negative regulation of protein kinase activity
0.35	GO:0009749	response to glucose
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.35	GO:0001678	cellular glucose homeostasis

0.75	GO:0004725	protein tyrosine phosphatase activity
0.36	GO:0033549	MAP kinase phosphatase activity
0.34	GO:0019198	transmembrane receptor protein phosphatase activity

0.50	GO:0005856	cytoskeleton
0.40	GO:0044446	intracellular organelle part
0.37	GO:0099512	supramolecular fiber
0.36	GO:0005634	nucleus
0.35	GO:0008021	synaptic vesicle
0.35	GO:0030141	secretory granule
0.35	GO:0043235	receptor complex
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0012506	vesicle membrane
0.34	GO:0098805	whole membrane

0.75

GO:0004725

sp|Q4KMG0|CDON_HUMAN
Cell adhesion molecule-related/down-regulated by oncogenes
Search

CDON

0.93	Cell adhesion associated, oncogene regulated

0.85	GO:0045663	positive regulation of myoblast differentiation
0.81	GO:0007224	smoothened signaling pathway
0.77	GO:0045664	regulation of neuron differentiation
0.76	GO:0048598	embryonic morphogenesis
0.62	GO:0014816	skeletal muscle satellite cell differentiation
0.61	GO:0043497	regulation of protein heterodimerization activity
0.60	GO:0048643	positive regulation of skeletal muscle tissue development
0.59	GO:2000179	positive regulation of neural precursor cell proliferation
0.59	GO:0007520	myoblast fusion
0.59	GO:0002088	lens development in camera-type eye

0.36

GO:0005515

protein binding

0.65	GO:0005887	integral component of plasma membrane
0.37	GO:0009986	cell surface
0.36	GO:0005654	nucleoplasm
0.35	GO:0031012	extracellular matrix

sp|Q4KMG9|TM52B_HUMAN
Transmembrane protein 52B
Search

TMEM52B

0.97	Transmembrane protein 52B

0.39	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q4KMP7|TB10B_HUMAN
TBC1 domain family member 10B
Search

TBC1D10B

0.95	TBC1 domain family member 3

0.79	GO:0042147	retrograde transport, endosome to Golgi
0.75	GO:0043547	positive regulation of GTPase activity
0.66	GO:0031338	regulation of vesicle fusion
0.56	GO:0006886	intracellular protein transport
0.49	GO:1902017	regulation of cilium assembly
0.42	GO:0097202	activation of cysteine-type endopeptidase activity

0.75	GO:0005096	GTPase activator activity
0.63	GO:0017137	Rab GTPase binding
0.41	GO:0030165	PDZ domain binding
0.40	GO:0045296	cadherin binding
0.36	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0003723	RNA binding

0.67	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.54	GO:0012505	endomembrane system
0.38	GO:0005902	microvillus
0.37	GO:0070062	extracellular exosome

sp|Q4KMQ1|TPRN_HUMAN
Taperin
Search

TPRN

0.91

Taperin

0.80	GO:0007605	sensory perception of sound
0.33	GO:0006511	ubiquitin-dependent protein catabolic process
0.32	GO:0040017	positive regulation of locomotion
0.32	GO:0006897	endocytosis
0.32	GO:0006090	pyruvate metabolic process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0071897	DNA biosynthetic process
0.32	GO:0000160	phosphorelay signal transduction system
0.31	GO:0006355	regulation of transcription, DNA-templated

0.82	GO:0019902	phosphatase binding
0.33	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding

0.54	GO:0032420	stereocilium
0.32	GO:0045254	pyruvate dehydrogenase complex
0.32	GO:0005759	mitochondrial matrix
0.32	GO:0045202	synapse
0.30	GO:0016020	membrane

0.32

EC:2.3.1.12

GO:0004742

sp|Q4KMQ2|ANO6_HUMAN
Anoctamin-6
Search

ANO6

0.67

Anoctamin

0.86	GO:0002407	dendritic cell chemotaxis
0.85	GO:0061588	calcium activated phospholipid scrambling
0.85	GO:0030501	positive regulation of bone mineralization
0.81	GO:0034767	positive regulation of ion transmembrane transport
0.80	GO:0007596	blood coagulation
0.76	GO:1902476	chloride transmembrane transport
0.58	GO:0097045	phosphatidylserine exposure on blood platelet
0.58	GO:0002543	activation of blood coagulation via clotting cascade
0.57	GO:0035630	bone mineralization involved in bone maturation
0.57	GO:0045794	negative regulation of cell volume

0.68	GO:0046983	protein dimerization activity
0.56	GO:0017128	phospholipid scramblase activity
0.56	GO:0005229	intracellular calcium activated chloride channel activity
0.53	GO:0005227	calcium activated cation channel activity
0.51	GO:0005247	voltage-gated chloride channel activity
0.49	GO:0042802	identical protein binding

0.52	GO:0034707	chloride channel complex
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0009986	cell surface
0.36	GO:0035579	specific granule membrane
0.36	GO:0070821	tertiary granule membrane

sp|Q4KMX7|F106A_HUMAN
Protein FAM106A
Search

sp|Q4KMZ1|IQCC_HUMAN
IQ domain-containing protein C
Search

IQCC

0.97	LOW QUALITY PROTEIN: IQ domain-containing protein C

0.52	GO:0035556	intracellular signal transduction
0.40	GO:0001731	formation of translation preinitiation complex
0.40	GO:0006446	regulation of translational initiation

0.58	GO:0019905	syntaxin binding
0.38	GO:0003743	translation initiation factor activity

0.40	GO:0005622	intracellular
0.36	GO:1990904	ribonucleoprotein complex
0.36	GO:0043234	protein complex

sp|Q4KMZ8|NKAI1_HUMAN
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1
Search

NKAIN1

0.97	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

0.49

GO:0002028

regulation of sodium ion transport

0.41

GO:0051117

ATPase binding

0.39	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q4KN68|CT062_HUMAN
Uncharacterized protein encoded by LINC01620
Search

sp|Q4KWH8|PLCH1_HUMAN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
Search

PLCH1

0.52	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

0.80	GO:0048015	phosphatidylinositol-mediated signaling
0.66	GO:0016042	lipid catabolic process
0.61	GO:0043647	inositol phosphate metabolic process

0.86	GO:0050429	calcium-dependent phospholipase C activity
0.75	GO:0004435	phosphatidylinositol phospholipase C activity
0.64	GO:0005509	calcium ion binding
0.59	GO:0004871	signal transducer activity

0.63	GO:0005829	cytosol
0.52	GO:0043231	intracellular membrane-bounded organelle
0.46	GO:0005886	plasma membrane

0.75	EC:3.1.4.11	GO:0004435
0.75	KEGG:R03435	GO:0004435

sp|Q4L180|FIL1L_HUMAN
Filamin A-interacting protein 1-like
Search

FILIP1L

0.95	Filamin A interacting protein 1 like

0.32

GO:0006807

nitrogen compound metabolic process

0.61	GO:0015629	actin cytoskeleton
0.61	GO:0005730	nucleolus
0.48	GO:0005886	plasma membrane
0.42	GO:0005737	cytoplasm

sp|Q4L235|ACSF4_HUMAN
Acyl-CoA synthetase family member 4
Search

AASDH

0.88	Aminoadipate-semialdehyde dehydrogenase

0.80	GO:0043041	amino acid activation for nonribosomal peptide biosynthetic process
0.76	GO:0019482	beta-alanine metabolic process

0.30

GO:0003824

catalytic activity

0.30

GO:0031224

intrinsic component of membrane

sp|Q4LDE5|SVEP1_HUMAN
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1
Search

SVEP1

0.57	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

0.59	GO:0001945	lymph vessel development
0.37	GO:0007155	cell adhesion

0.70	GO:0005509	calcium ion binding
0.52	GO:0003682	chromatin binding

0.50	GO:0005615	extracellular space
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q4LDG9|DNAL1_HUMAN
Dynein light chain 1, axonemal
Search

DNAL1

0.95	Dynein axonemal light chain 1

0.84	GO:0036158	outer dynein arm assembly
0.37	GO:0035383	thioester metabolic process
0.37	GO:0006631	fatty acid metabolic process
0.37	GO:0016973	poly(A)+ mRNA export from nucleus
0.36	GO:0006732	coenzyme metabolic process
0.34	GO:0006793	phosphorus metabolic process
0.33	GO:0055114	oxidation-reduction process

0.84	GO:0045504	dynein heavy chain binding
0.82	GO:0043014	alpha-tubulin binding
0.50	GO:0003774	motor activity
0.39	GO:0047617	acyl-CoA hydrolase activity
0.37	GO:0030246	carbohydrate binding
0.34	GO:0003723	RNA binding
0.33	GO:0016491	oxidoreductase activity

0.52	GO:0030286	dynein complex
0.50	GO:0005874	microtubule
0.48	GO:0042995	cell projection
0.41	GO:0099568	cytoplasmic region
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39

EC:3.1.2 EC:3.1.2.20

GO:0047617

sp|Q4LDR2|CTXN3_HUMAN
Cortexin-3
Search

CTXN3

0.94	Cortexin-3

0.30

GO:0044425

membrane part

sp|Q4LE39|ARI4B_HUMAN
AT-rich interactive domain-containing protein 4B
Search

ARID4B

0.96	LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 4B

0.63	GO:0097368	establishment of Sertoli cell barrier
0.63	GO:0036124	histone H3-K9 trimethylation
0.60	GO:0034773	histone H4-K20 trimethylation
0.60	GO:0006349	regulation of gene expression by genetic imprinting
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0007283	spermatogenesis
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0010628	positive regulation of gene expression
0.36	GO:0016575	histone deacetylation

0.54	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0004407	histone deacetylase activity
0.35	GO:0005515	protein binding
0.35	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.36	GO:0005742	mitochondrial outer membrane translocase complex
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004407

sp|Q4LEZ3|AARD_HUMAN
Alanine and arginine-rich domain-containing protein
Search

AARD

0.97	Alanine and arginine-rich domain-containing protein (Fragment)

0.84

GO:0030324

lung development

sp|Q4QY38|DB134_HUMAN
Beta-defensin 134
Search

DEFB134

0.62	Beta-defensin

0.79	GO:0045087	innate immune response
0.70	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.49	GO:0009986	cell surface

sp|Q4U2R6|RM51_HUMAN
39S ribosomal protein L51, mitochondrial
Search

MRPL51

0.97	Mitochondrial ribosomal protein L51

0.48	GO:0043043	peptide biosynthetic process
0.45	GO:0044267	cellular protein metabolic process
0.44	GO:0010467	gene expression
0.44	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.62	GO:0005762	mitochondrial large ribosomal subunit
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

0.32

GO:0016787

sp|Q4U2R8|S22A6_HUMAN
Solute carrier family 22 member 6
Search

SLC22A6

0.86	Solute carrier family 22 (Organic anion transporter), member 6, like

0.62	GO:0097254	renal tubular secretion
0.62	GO:0015742	alpha-ketoglutarate transport
0.52	GO:0055085	transmembrane transport
0.52	GO:0043252	sodium-independent organic anion transport
0.51	GO:0015698	inorganic anion transport
0.50	GO:0015747	urate transport
0.42	GO:0031427	response to methotrexate
0.39	GO:0051260	protein homooligomerization
0.33	GO:0009636	response to toxic substance

0.58	GO:0005452	inorganic anion exchanger activity
0.52	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.50	GO:0015143	urate transmembrane transporter activity
0.40	GO:0031404	chloride ion binding
0.39	GO:0015301	anion:anion antiporter activity
0.38	GO:0042803	protein homodimerization activity

0.57	GO:0016323	basolateral plasma membrane
0.50	GO:0005887	integral component of plasma membrane
0.40	GO:0005901	caveola
0.38	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

sp|Q4UJ75|A20A4_HUMAN
Ankyrin repeat domain-containing protein 20A4
Search

0.95	Ankyrin repeat domain-containing protein 20B

0.51	GO:0045599	negative regulation of fat cell differentiation
0.48	GO:0040015	negative regulation of multicellular organism growth
0.47	GO:0060259	regulation of feeding behavior
0.47	GO:0046621	negative regulation of organ growth
0.47	GO:0046627	negative regulation of insulin receptor signaling pathway
0.46	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.46	GO:0019217	regulation of fatty acid metabolic process
0.45	GO:0042593	glucose homeostasis
0.38	GO:0065009	regulation of molecular function
0.36	GO:2001141	regulation of RNA biosynthetic process

0.42	GO:0005515	protein binding
0.42	GO:0008200	ion channel inhibitor activity
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003677	DNA binding

0.55	GO:0005813	centrosome
0.46	GO:0005884	actin filament
0.45	GO:0005886	plasma membrane
0.44	GO:0070062	extracellular exosome
0.40	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q4V321|GAG13_HUMAN
G antigen 13
Search

0.97	G antigen 5

0.63

GO:0006968

cellular defense response

0.58

GO:0005515

protein binding

sp|Q4V326|GAG2E_HUMAN
G antigen 2E
Search

0.97	G antigen 5

0.63

GO:0006968

cellular defense response

0.58

GO:0005515

protein binding

sp|Q4V328|GRAP1_HUMAN
GRIP1-associated protein 1
Search

GRIPAP1

0.91	GRIP1-associated protein 1 isoform B

0.52	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane
0.52	GO:1905244	regulation of modification of synaptic structure
0.38	GO:0051260	protein homooligomerization
0.37	GO:0071805	potassium ion transmembrane transport
0.37	GO:0006914	autophagy

0.42	GO:0005515	protein binding
0.38	GO:0005249	voltage-gated potassium channel activity

0.68	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.53	GO:0098837	postsynaptic recycling endosome
0.48	GO:0055038	recycling endosome membrane
0.48	GO:0031901	early endosome membrane
0.47	GO:0030425	dendrite
0.46	GO:0030424	axon
0.46	GO:0072562	blood microparticle
0.45	GO:0030054	cell junction
0.38	GO:0008076	voltage-gated potassium channel complex

sp|Q4V339|CBWD6_HUMAN
COBW domain-containing protein 6
Search

0.71	Cobalamin synthase W domain-containing protein 3

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding

sp|Q4V348|Z658B_HUMAN
Zinc finger protein 658B
Search

0.71	Zinc finger protein 658

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.44	GO:0071294	cellular response to zinc ion
0.40	GO:0006351	transcription, DNA-templated
0.39	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0042254	ribosome biogenesis

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity

0.51	GO:0031965	nuclear membrane
0.46	GO:0005829	cytosol
0.33	GO:0031981	nuclear lumen
0.33	GO:0015630	microtubule cytoskeleton
0.32	GO:0005886	plasma membrane

sp|Q4V9L6|TM119_HUMAN
Transmembrane protein 119
Search

TMEM119

0.49	Transmembrane domain-containing protein (Fragment)

0.83	GO:0001503	ossification
0.68	GO:1903012	positive regulation of bone development
0.68	GO:0033690	positive regulation of osteoblast proliferation
0.66	GO:0030501	positive regulation of bone mineralization
0.65	GO:0045669	positive regulation of osteoblast differentiation
0.63	GO:0048515	spermatid differentiation
0.41	GO:0031214	biomineral tissue development

0.34

GO:0005515

protein binding

0.55	GO:0005783	endoplasmic reticulum
0.46	GO:0005886	plasma membrane
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|Q4VC05|BCL7A_HUMAN
B-cell CLL/lymphoma 7 protein family member A
Search

BCL7A

0.93	BCL tumor suppressor 7A

sp|Q4VC12|MSS51_HUMAN
Putative protein MSS51 homolog, mitochondrial
Search

MSS51

0.97	MSS51 mitochondrial translational activator

0.85

GO:0035176

social behavior

0.38

GO:0046872

metal ion binding

sp|Q4VC31|CCD58_HUMAN
Coiled-coil domain-containing protein 58
Search

CCDC58

0.96	Coiled-coil domain-containing protein 58

0.61

GO:0005739

mitochondrion

sp|Q4VC39|HIG2B_HUMAN
Putative HIG1 domain family member 2B
Search

HIGD2A

0.59	HIG1 hypoxia inducible domain family member 2B

0.64	GO:0097250	mitochondrial respiratory chain supercomplex assembly
0.49	GO:0043066	negative regulation of apoptotic process
0.34	GO:0055114	oxidation-reduction process

0.47	GO:0005739	mitochondrion
0.36	GO:0019866	organelle inner membrane
0.35	GO:0070469	respiratory chain
0.30	GO:0031224	intrinsic component of membrane

sp|Q4VC44|FWCH1_HUMAN
FLYWCH-type zinc finger-containing protein 1
Search

0.10	FLYWCH-type zinc finger-containing protein 1

0.30	GO:0097159	organic cyclic compound binding
0.30	GO:0043167	ion binding
0.30	GO:1901363	heterocyclic compound binding

0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0005737	cytoplasm
0.30	GO:0005634	nucleus
0.30	GO:0044422	organelle part

sp|Q4VCS5|AMOT_HUMAN
Angiomotin
Search

AMOT

0.86	Angiomotin like 1

0.83	GO:0003365	establishment of cell polarity involved in ameboidal cell migration
0.82	GO:0043534	blood vessel endothelial cell migration
0.80	GO:0035329	hippo signaling
0.78	GO:0034260	negative regulation of GTPase activity
0.78	GO:0016525	negative regulation of angiogenesis
0.77	GO:0001702	gastrulation with mouth forming second
0.77	GO:0040019	positive regulation of embryonic development
0.77	GO:0042074	cell migration involved in gastrulation
0.76	GO:0001570	vasculogenesis
0.74	GO:0030334	regulation of cell migration

0.85	GO:0043532	angiostatin binding
0.61	GO:0004872	receptor activity
0.45	GO:0042802	identical protein binding

0.77	GO:0030027	lamellipodium
0.77	GO:0001726	ruffle
0.77	GO:0005884	actin filament
0.76	GO:0008180	COP9 signalosome
0.76	GO:0009897	external side of plasma membrane
0.75	GO:0030139	endocytic vesicle
0.73	GO:0005923	bicellular tight junction
0.45	GO:0097517	contractile actin filament bundle
0.45	GO:0042641	actomyosin
0.40	GO:0016324	apical plasma membrane

sp|Q4VNC0|AT135_HUMAN
Probable cation-transporting ATPase 13A5
Search

ATP13A5

0.63	Cation-transporting ATPase

0.60	GO:0006812	cation transport
0.51	GO:0006874	cellular calcium ion homeostasis
0.46	GO:0099131	ATP hydrolysis coupled ion transmembrane transport
0.43	GO:0098660	inorganic ion transmembrane transport

0.60	GO:0016887	ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.50	GO:0015085	calcium ion transmembrane transporter activity
0.47	GO:0022853	active ion transmembrane transporter activity
0.45	GO:0015399	primary active transmembrane transporter activity

0.46	GO:0005887	integral component of plasma membrane
0.41	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0044444	cytoplasmic part

0.60

GO:0016887

sp|Q4VNC1|AT134_HUMAN
Probable cation-transporting ATPase 13A4
Search

ATP13A4

0.63	Cation-transporting ATPase

0.60	GO:0006812	cation transport
0.51	GO:0006874	cellular calcium ion homeostasis
0.46	GO:0099131	ATP hydrolysis coupled ion transmembrane transport
0.43	GO:0098660	inorganic ion transmembrane transport

0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.50	GO:0015085	calcium ion transmembrane transporter activity
0.47	GO:0022853	active ion transmembrane transporter activity
0.45	GO:0015399	primary active transmembrane transporter activity
0.32	GO:0003723	RNA binding

0.46	GO:0005887	integral component of plasma membrane
0.41	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.33	GO:0044444	cytoplasmic part

0.61

GO:0016887

sp|Q4VX62|CF099_HUMAN
Putative uncharacterized protein C6orf99
Search

sp|Q4VX76|SYTL3_HUMAN
Synaptotagmin-like protein 3
Search

SYTL3

0.97	Synaptotagmin like 3

0.74	GO:0006887	exocytosis
0.65	GO:0006886	intracellular protein transport
0.50	GO:0017158	regulation of calcium ion-dependent exocytosis
0.49	GO:0048489	synaptic vesicle transport
0.49	GO:0099504	synaptic vesicle cycle
0.49	GO:0006906	vesicle fusion
0.49	GO:0099643	signal release from synapse
0.49	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.46	GO:0006836	neurotransmitter transport
0.45	GO:0001505	regulation of neurotransmitter levels

0.79	GO:0017137	Rab GTPase binding
0.77	GO:0005544	calcium-dependent phospholipid binding
0.61	GO:0042043	neurexin family protein binding
0.49	GO:0019905	syntaxin binding
0.48	GO:0030276	clathrin binding
0.44	GO:0005509	calcium ion binding
0.41	GO:0035004	phosphatidylinositol 3-kinase activity
0.40	GO:0035091	phosphatidylinositol binding
0.35	GO:0052742	phosphatidylinositol kinase activity
0.34	GO:0016307	phosphatidylinositol phosphate kinase activity

0.55	GO:0019897	extrinsic component of plasma membrane
0.48	GO:0070382	exocytic vesicle
0.48	GO:0098793	presynapse
0.34	GO:0005942	phosphatidylinositol 3-kinase complex
0.34	GO:0005634	nucleus
0.32	GO:0070062	extracellular exosome
0.32	GO:0030136	clathrin-coated vesicle
0.32	GO:0005840	ribosome
0.32	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.41

GO:0035004

sp|Q4VXA5|KHDC1_HUMAN
KH homology domain-containing protein 1
Search

KHDC1

0.97	KH homology domain-containing protein 1

0.40	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.39	GO:0006915	apoptotic process

0.59	GO:0003723	RNA binding
0.41	GO:0042802	identical protein binding

0.35	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q4VXF1|F74A3_HUMAN
Putative protein FAM74A3
Search

sp|Q4VXU2|PAP1L_HUMAN
Polyadenylate-binding protein 1-like
Search

0.61	Polyadenylate-binding protein 1-B

0.57	GO:0048096	chromatin-mediated maintenance of transcription
0.57	GO:0001556	oocyte maturation
0.55	GO:0051647	nucleus localization
0.53	GO:0006378	mRNA polyadenylation
0.40	GO:0048513	animal organ development
0.39	GO:0043488	regulation of mRNA stability
0.38	GO:0072359	circulatory system development
0.37	GO:0002520	immune system development
0.36	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.35	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

0.58	GO:0003723	RNA binding
0.35	GO:0031370	eukaryotic initiation factor 4G binding
0.35	GO:0043621	protein self-association

0.48	GO:0005737	cytoplasm
0.37	GO:0035770	ribonucleoprotein granule
0.37	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.35	GO:0005844	polysome

sp|Q4W4Y0|CN028_HUMAN
Uncharacterized protein C14orf28
Search

sp|Q4W5G0|TIGD2_HUMAN
Tigger transposable element-derived protein 2
Search

TIGD2

0.94	Tigger transposable element-derived protein 2

0.35	GO:0007417	central nervous system development
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.31	GO:0006351	transcription, DNA-templated

0.54	GO:0003677	DNA binding
0.40	GO:0003729	mRNA binding
0.34	GO:0004519	endonuclease activity
0.31	GO:0008270	zinc ion binding

0.39	GO:0005634	nucleus
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005737	cytoplasm
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q4W5N1|ABCAB_HUMAN
Putative ATP-binding cassette sub-family A member 11
Search

0.11	Putative ATP-binding cassette sub-family A member 11

0.55	GO:0006869	lipid transport
0.53	GO:0055085	transmembrane transport
0.35	GO:0042908	xenobiotic transport
0.34	GO:0015893	drug transport

0.63	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0042910	xenobiotic transmembrane transporter activity
0.34	GO:0015238	drug transmembrane transporter activity

0.46	GO:0043231	intracellular membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.43	GO:0044444	cytoplasmic part
0.42	GO:0031974	membrane-enclosed lumen
0.42	GO:0031090	organelle membrane
0.41	GO:0031975	envelope
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q4W5P6|TM155_HUMAN
Protein TMEM155
Search

sp|Q4ZG55|GREB1_HUMAN
Protein GREB1
Search

GREB1

0.90	Growth regulation by estrogen in breast cancer 1 like

0.64

GO:0001822

kidney development

0.58	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q4ZHG4|FNDC1_HUMAN
Fibronectin type III domain-containing protein 1
Search

FNDC1

0.91	Fibronectin type III domain-containing protein 1

0.46	GO:0010666	positive regulation of cardiac muscle cell apoptotic process
0.44	GO:0071456	cellular response to hypoxia
0.42	GO:0051223	regulation of protein transport
0.42	GO:0001934	positive regulation of protein phosphorylation

0.79	GO:0016607	nuclear speck
0.42	GO:0005576	extracellular region
0.42	GO:0005911	cell-cell junction
0.38	GO:0031966	mitochondrial membrane
0.37	GO:0005886	plasma membrane

sp|Q4ZIN3|MBRL_HUMAN
Membralin
Search

TMEM259

0.92	Transmembrane protein 259

0.67	GO:1904294	positive regulation of ERAD pathway
0.63	GO:1901215	negative regulation of neuron death
0.61	GO:0034976	response to endoplasmic reticulum stress

0.55	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|Q4ZJI4|SL9B1_HUMAN
Sodium/hydrogen exchanger 9B1
Search

SLC9B2

0.93	Mitochondrial sodium/hydrogen exchanger NHA2

0.72	GO:0006814	sodium ion transport
0.62	GO:1902600	hydrogen ion transmembrane transport
0.52	GO:0030317	flagellated sperm motility
0.52	GO:2001206	positive regulation of osteoclast development
0.50	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.45	GO:0072583	clathrin-dependent endocytosis
0.40	GO:0051453	regulation of intracellular pH
0.39	GO:0007338	single fertilization
0.34	GO:0007018	microtubule-based movement
0.33	GO:0055114	oxidation-reduction process

0.74	GO:0015299	solute:proton antiporter activity
0.47	GO:0015491	cation:cation antiporter activity
0.46	GO:0015081	sodium ion transmembrane transporter activity
0.45	GO:0042802	identical protein binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.53	GO:0097228	sperm principal piece
0.51	GO:0030672	synaptic vesicle membrane
0.49	GO:0016323	basolateral plasma membrane
0.48	GO:0010008	endosome membrane
0.42	GO:0031966	mitochondrial membrane
0.37	GO:0030054	cell junction
0.34	GO:0019866	organelle inner membrane
0.34	GO:0016324	apical plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016491

sp|Q502W6|VWA3B_HUMAN
von Willebrand factor A domain-containing protein 3B
Search

VWA3B

0.97	von Willebrand factor A domain-containing protein 3B

0.43	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q502W7|CCD38_HUMAN
Coiled-coil domain-containing protein 38
Search

CCDC38

0.97	Coiled-coil domain-containing protein 38

0.78	GO:0005813	centrosome
0.37	GO:0005737	cytoplasm

sp|Q502X0|MORN2_HUMAN
MORN repeat-containing protein 2
Search

MORN2

0.97	MORN repeat-containing protein 2

0.52	GO:0034968	histone lysine methylation
0.48	GO:0007283	spermatogenesis
0.48	GO:0016310	phosphorylation
0.45	GO:0030154	cell differentiation

0.52	GO:0018024	histone-lysine N-methyltransferase activity
0.49	GO:0016301	kinase activity
0.39	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding

0.49	GO:0001669	acrosomal vesicle
0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.52

EC:2.1.1.43

GO:0018024

sp|Q504Q3|PAN2_HUMAN
PAB-dependent poly(A)-specific ribonuclease subunit PAN2
Search

PAN2

0.76	PAN2-PAN3 deadenylation complex catalytic subunit PAN2

0.81	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.79	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.71	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.66	GO:0006397	mRNA processing
0.36	GO:0006099	tricarboxylic acid cycle
0.35	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic
0.33	GO:0007165	signal transduction
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.80	GO:0004535	poly(A)-specific ribonuclease activity
0.51	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.38	GO:0004108	citrate (Si)-synthase activity
0.35	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.80	GO:0031251	PAN complex
0.76	GO:0000932	P-body
0.58	GO:0005634	nucleus
0.34	GO:0005829	cytosol

0.80

EC:3.1.13.4

GO:0004535

sp|Q504T8|MIDN_HUMAN
Midnolin
Search

MIDN

0.94	LOW QUALITY PROTEIN: midnolin

0.54	GO:0033132	negative regulation of glucokinase activity
0.52	GO:0046676	negative regulation of insulin secretion

0.48

GO:0019900

kinase binding

0.72	GO:0005730	nucleolus
0.68	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q504U0|CD046_HUMAN
Renal cancer differentiation gene 1 protein
Search

0.50

GO:0005515

protein binding

0.49

GO:0005737

cytoplasm

sp|Q504Y0|S39AC_HUMAN
Zinc transporter ZIP12
Search

SLC39A12

0.93	Zinc transporter ZIP12 isoform B

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.42	GO:0006882	cellular zinc ion homeostasis
0.42	GO:0031113	regulation of microtubule polymerization
0.41	GO:0010975	regulation of neuron projection development
0.39	GO:0072511	divalent inorganic cation transport
0.37	GO:0007165	signal transduction

0.68	GO:0046873	metal ion transmembrane transporter activity
0.40	GO:0072509	divalent inorganic cation transmembrane transporter activity

0.40	GO:0048471	perinuclear region of cytoplasm
0.38	GO:1903561	extracellular vesicle
0.38	GO:0005887	integral component of plasma membrane

sp|Q504Y2|PKDCC_HUMAN
Extracellular tyrosine-protein kinase PKDCC
Search

PKDCC

0.87	Extracellular tyrosine-protein kinase PKDCC

0.59	GO:0006468	protein phosphorylation
0.57	GO:0042997	negative regulation of Golgi to plasma membrane protein transport
0.56	GO:0032332	positive regulation of chondrocyte differentiation
0.55	GO:0030282	bone mineralization
0.55	GO:0048286	lung alveolus development
0.55	GO:0048566	embryonic digestive tract development
0.55	GO:0030501	positive regulation of bone mineralization
0.54	GO:0060021	palate development
0.54	GO:0035264	multicellular organism growth
0.53	GO:0035108	limb morphogenesis

0.60	GO:0016301	kinase activity
0.58	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.55	GO:0140096	catalytic activity, acting on a protein
0.51	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005794	Golgi apparatus
0.46	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.58

GO:0016773

sp|Q504Y3|ZCPW2_HUMAN
Zinc finger CW-type PWWP domain protein 2
Search

ZCWPW2

0.96	Zinc finger CW-type PWWP domain protein 2

0.63

GO:0008270

zinc ion binding

0.30

GO:0044425

membrane part

sp|Q50LG9|LRC24_HUMAN
Leucine-rich repeat-containing protein 24
Search

LRRC24

0.95	LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 24

0.58	GO:0051965	positive regulation of synapse assembly
0.36	GO:0008056	ocellus development
0.35	GO:0046426	negative regulation of JAK-STAT cascade
0.35	GO:0006469	negative regulation of protein kinase activity
0.35	GO:0019221	cytokine-mediated signaling pathway

0.35	GO:0004860	protein kinase inhibitor activity
0.34	GO:0005515	protein binding

0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q52LA3|LIN52_HUMAN
Protein lin-52 homolog
Search

LIN52

0.97	Lin-52 DREAM MuvB core complex component

0.67	GO:0007049	cell cycle
0.58	GO:0006351	transcription, DNA-templated
0.34	GO:0051726	regulation of cell cycle
0.33	GO:0007275	multicellular organism development

0.86

GO:0070176

DRM complex

sp|Q52LC2|VAS1L_HUMAN
V-type proton ATPase subunit S1-like protein
Search

ATP6AP1L

0.97	ATPase H+ transporting accessory protein 1 like

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.35	GO:1901207	regulation of heart looping
0.35	GO:0008057	eye pigment granule organization
0.35	GO:0003406	retinal pigment epithelium development
0.35	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.35	GO:0070121	Kupffer's vesicle development
0.35	GO:0032438	melanosome organization
0.35	GO:1902017	regulation of cilium assembly
0.34	GO:0030641	regulation of cellular pH
0.34	GO:0072659	protein localization to plasma membrane

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.33	GO:0097027	ubiquitin-protein transferase activator activity
0.33	GO:0010997	anaphase-promoting complex binding

0.81	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q52LD8|RFTN2_HUMAN
Raftlin-2
Search

RFTN2

0.97	Raftlin-2 isoform B

0.83	GO:0033227	dsRNA transport
0.82	GO:0043330	response to exogenous dsRNA
0.69	GO:0032596	protein transport into membrane raft
0.65	GO:0050851	antigen receptor-mediated signaling pathway
0.43	GO:0034138	toll-like receptor 3 signaling pathway
0.43	GO:0001765	membrane raft assembly
0.41	GO:0040007	growth
0.36	GO:0002457	T cell antigen processing and presentation
0.36	GO:0032620	interleukin-17 production

0.40

GO:0003725

double-stranded RNA binding

0.62	GO:0045121	membrane raft
0.42	GO:0005737	cytoplasm
0.40	GO:0005886	plasma membrane
0.40	GO:0097708	intracellular vesicle
0.38	GO:0012505	endomembrane system
0.37	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q52LG2|KR132_HUMAN
Keratin-associated protein 13-2
Search

0.97	Keratin-associated protein 14

0.65

GO:0031424

keratinization

0.39

GO:0005515

protein binding

0.75	GO:0005882	intermediate filament
0.53	GO:0005829	cytosol

sp|Q52LJ0|FA98B_HUMAN
Protein FAM98B
Search

0.77	GO:0008284	positive regulation of cell proliferation
0.72	GO:0008213	protein alkylation
0.71	GO:0010628	positive regulation of gene expression
0.66	GO:0043414	macromolecule methylation
0.64	GO:1900029	positive regulation of ruffle assembly
0.62	GO:0032418	lysosome localization
0.38	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation

0.72	GO:0008276	protein methyltransferase activity
0.64	GO:0042802	identical protein binding
0.38	GO:0003723	RNA binding

0.81	GO:0072669	tRNA-splicing ligase complex
0.61	GO:0005654	nucleoplasm
0.45	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0008276

sp|Q52LR7|EPC2_HUMAN
Enhancer of polycomb homolog 2
Search

EPC2

0.92	Enhancer of polycomb like protein 2

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.48	GO:0016573	histone acetylation
0.40	GO:0060319	primitive erythrocyte differentiation
0.39	GO:0045814	negative regulation of gene expression, epigenetic
0.38	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0006281	DNA repair

0.49

GO:0004402

histone acetyltransferase activity

0.84	GO:0032777	Piccolo NuA4 histone acetyltransferase complex
0.39	GO:0031965	nuclear membrane

0.49

GO:0004402

sp|Q52LW3|RHG29_HUMAN
Rho GTPase-activating protein 29
Search

ARHGAP29

0.92	Rho GTPase-activating protein 29

0.75	GO:0043547	positive regulation of GTPase activity
0.62	GO:0035556	intracellular signal transduction
0.36	GO:0051056	regulation of small GTPase mediated signal transduction

0.75	GO:0005096	GTPase activator activity
0.64	GO:0030165	PDZ domain binding
0.51	GO:0046872	metal ion binding

0.45

GO:0005622

intracellular

sp|Q52M58|CN177_HUMAN
Putative uncharacterized protein C14orf177
Search

sp|Q52M75|CE027_HUMAN
Putative uncharacterized protein encoded by LINC01554
Search

sp|Q52M93|Z585B_HUMAN
Zinc finger protein 585B
Search

0.60	Zinc finger protein 27

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.42	GO:0048522	positive regulation of cellular process
0.41	GO:0071156	regulation of cell cycle arrest
0.40	GO:0006366	transcription by RNA polymerase II
0.40	GO:0040017	positive regulation of locomotion
0.40	GO:0008285	negative regulation of cell proliferation
0.40	GO:0030334	regulation of cell migration

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.38	GO:0043228	non-membrane-bounded organelle
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044422	organelle part

sp|Q52MB2|CC184_HUMAN
Coiled-coil domain-containing protein 184
Search

CCDC184

0.97	Coiled-coil domain-containing protein 184

0.38

GO:0005515

protein binding

0.49

GO:0005737

cytoplasm

sp|Q52WX2|SBK1_HUMAN
Serine/threonine-protein kinase SBK1
Search

SBK1

0.93	Serine/threonine-protein kinase SBK1

0.63	GO:0006468	protein phosphorylation
0.50	GO:0018210	peptidyl-threonine modification
0.49	GO:0018209	peptidyl-serine modification
0.35	GO:0007420	brain development
0.33	GO:0007266	Rho protein signal transduction
0.33	GO:0031098	stress-activated protein kinase signaling cascade
0.33	GO:0032147	activation of protein kinase activity
0.33	GO:0043408	regulation of MAPK cascade
0.33	GO:0016477	cell migration
0.33	GO:0007346	regulation of mitotic cell cycle

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0048365	Rac GTPase binding
0.32	GO:0008080	N-acetyltransferase activity
0.31	GO:0003676	nucleic acid binding

0.45	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.67

GO:0004674

sp|Q537H7|SPT45_HUMAN
Spermatogenesis-associated protein 45
Search

SPATA45

0.97	Spermatogenesis-associated protein 45

sp|Q538Z0|LUZP6_HUMAN
Leucine zipper protein 6
Search

0.30

GO:0044425

membrane part

sp|Q53EL6|PDCD4_HUMAN
Programmed cell death protein 4
Search

PDCD4

0.96	Programmed Cell death 4 (Neoplastic transformation inhibitor)

0.85	GO:1904761	negative regulation of myofibroblast differentiation
0.85	GO:1905064	negative regulation of vascular smooth muscle cell differentiation
0.84	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.82	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.82	GO:2000353	positive regulation of endothelial cell apoptotic process
0.82	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.79	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.77	GO:0030509	BMP signaling pathway
0.76	GO:0050729	positive regulation of inflammatory response
0.76	GO:0071222	cellular response to lipopolysaccharide

0.40	GO:0003723	RNA binding
0.38	GO:0005515	protein binding

0.63	GO:0005829	cytosol
0.58	GO:0005634	nucleus

sp|Q53EL9|SEZ6_HUMAN
Seizure protein 6 homolog
Search

SEZ6

0.97	Seizure protein 6

0.58	GO:0060074	synapse maturation
0.57	GO:2000171	negative regulation of dendrite development
0.56	GO:0090036	regulation of protein kinase C signaling
0.56	GO:0021680	cerebellar Purkinje cell layer development
0.56	GO:1900006	positive regulation of dendrite development
0.55	GO:0008344	adult locomotory behavior
0.53	GO:0060079	excitatory postsynaptic potential

0.58	GO:0097440	apical dendrite
0.56	GO:0043198	dendritic shaft
0.55	GO:0043197	dendritic spine
0.53	GO:0043025	neuronal cell body
0.52	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005615	extracellular space
0.48	GO:0005783	endoplasmic reticulum
0.35	GO:0030054	cell junction
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q53EP0|FND3B_HUMAN
Fibronectin type III domain-containing protein 3B
Search

FNDC3B

0.94	Fibronectin type III domain-containing protein 3B

0.39	GO:0060510	Type II pneumocyte differentiation
0.38	GO:0045668	negative regulation of osteoblast differentiation
0.38	GO:0048146	positive regulation of fibroblast proliferation
0.38	GO:0045600	positive regulation of fat cell differentiation
0.38	GO:0034446	substrate adhesion-dependent cell spreading
0.37	GO:0016477	cell migration

0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|Q53EQ6|TIGD5_HUMAN
Tigger transposable element-derived protein 5
Search

TIGD5

0.97	LOW QUALITY PROTEIN: tigger transposable element-derived protein 5

0.54	GO:0003677	DNA binding
0.37	GO:0005515	protein binding

0.42

GO:0005634

nucleus

sp|Q53ET0|CRTC2_HUMAN
CREB-regulated transcription coactivator 2
Search

CRTC2

0.95	CREB-regulated transcription coactivator 2

0.85	GO:0032793	positive regulation of CREB transcription factor activity
0.79	GO:0051289	protein homotetramerization
0.63	GO:0043970	histone H3-K9 acetylation
0.58	GO:0042593	glucose homeostasis
0.57	GO:1901998	toxin transport
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:0019319	hexose biosynthetic process
0.53	GO:0006006	glucose metabolic process
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0009628	response to abiotic stimulus

0.84	GO:0008140	cAMP response element binding protein binding
0.40	GO:0003682	chromatin binding
0.35	GO:0046873	metal ion transmembrane transporter activity

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.49	GO:0005737	cytoplasm
0.45	GO:0044446	intracellular organelle part
0.39	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q53EU6|GPAT3_HUMAN
Glycerol-3-phosphate acyltransferase 3
Search

GPAT3

0.94	Glycerol-3-phosphate acyltransferase 3

0.57	GO:0019432	triglyceride biosynthetic process
0.50	GO:0032006	regulation of TOR signaling
0.49	GO:0002071	glandular epithelial cell maturation
0.47	GO:0046339	diacylglycerol metabolic process
0.47	GO:0007595	lactation
0.46	GO:0006656	phosphatidylcholine biosynthetic process
0.46	GO:0040014	regulation of multicellular organism growth
0.43	GO:0035383	thioester metabolic process
0.42	GO:0016024	CDP-diacylglycerol biosynthetic process
0.41	GO:0006631	fatty acid metabolic process

0.61

GO:0016746

transferase activity, transferring acyl groups

0.51	GO:0005783	endoplasmic reticulum
0.49	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.47	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.61

GO:0016746

sp|Q53EV4|LRC23_HUMAN
Leucine-rich repeat-containing protein 23
Search

LRRC23

0.97	Leucine-rich repeat-containing protein 23

0.45	GO:0006757	ATP generation from ADP
0.44	GO:0006090	pyruvate metabolic process
0.44	GO:0016052	carbohydrate catabolic process
0.43	GO:0046496	nicotinamide nucleotide metabolic process
0.37	GO:0006470	protein dephosphorylation
0.36	GO:0009190	cyclic nucleotide biosynthetic process
0.34	GO:0035556	intracellular signal transduction

0.47	GO:0004634	phosphopyruvate hydratase activity
0.45	GO:0004807	triose-phosphate isomerase activity
0.42	GO:0000287	magnesium ion binding
0.37	GO:0004721	phosphoprotein phosphatase activity
0.36	GO:0016849	phosphorus-oxygen lyase activity
0.34	GO:0016301	kinase activity

0.53	GO:0005829	cytosol
0.41	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

0.47	EC:4.2.1.11	GO:0004634
0.45	KEGG:R01015	GO:0004807

sp|Q53EZ4|CEP55_HUMAN
Centrosomal protein of 55 kDa
Search

CEP55

0.97	Centrosomal protein of

0.84	GO:0000920	cell separation after cytokinesis
0.83	GO:1904888	cranial skeletal system development
0.79	GO:0000281	mitotic cytokinesis
0.77	GO:0072001	renal system development
0.64	GO:0045184	establishment of protein localization
0.47	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.47	GO:0021549	cerebellum development
0.47	GO:0051896	regulation of protein kinase B signaling
0.44	GO:0007080	mitotic metaphase plate congression
0.43	GO:0006997	nucleus organization

0.38	GO:0005515	protein binding
0.34	GO:0004930	G-protein coupled receptor activity

0.84	GO:0090543	Flemming body
0.80	GO:0045171	intercellular bridge
0.74	GO:0005813	centrosome
0.54	GO:0005886	plasma membrane
0.47	GO:0032154	cleavage furrow
0.46	GO:0005814	centriole
0.30	GO:0031224	intrinsic component of membrane

sp|Q53F19|NCBP3_HUMAN
Nuclear cap-binding protein subunit 3
Search

NCBP3

0.97	Nuclear cap-binding protein subunit 3

0.69	GO:0051607	defense response to virus
0.46	GO:0051028	mRNA transport
0.46	GO:0006370	7-methylguanosine mRNA capping

0.85	GO:0000340	RNA 7-methylguanosine cap binding
0.76	GO:0003729	mRNA binding
0.36	GO:0005515	protein binding

0.71	GO:0016607	nuclear speck
0.46	GO:0005737	cytoplasm
0.39	GO:0034518	RNA cap binding complex

sp|Q53F39|MPPE1_HUMAN
Metallophosphoesterase 1
Search

MPPE1

0.94	Metallophosphoesterase 1

0.77	GO:0006888	ER to Golgi vesicle-mediated transport
0.48	GO:0006506	GPI anchor biosynthetic process

0.50	GO:0016787	hydrolase activity
0.46	GO:0034235	GPI anchor binding
0.42	GO:0030145	manganese ion binding
0.34	GO:0005515	protein binding

0.51	GO:0005794	Golgi apparatus
0.49	GO:0005654	nucleoplasm
0.46	GO:0070971	endoplasmic reticulum exit site
0.45	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.44	GO:0005801	cis-Golgi network
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016787

sp|Q53FA7|QORX_HUMAN
Quinone oxidoreductase PIG3
Search

TP53I3

0.61	Quinone oxidoreductase PIG3

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006739	NADP metabolic process
0.34	GO:0042981	regulation of apoptotic process

0.55	GO:0003960	NADPH:quinone reductase activity
0.52	GO:0070402	NADPH binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0048038	quinone binding
0.35	GO:0003779	actin binding
0.33	GO:0004022	alcohol dehydrogenase (NAD) activity

0.35	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.55

EC:1.6.5.5

GO:0003960

sp|Q53FD0|ZC21C_HUMAN
Zinc finger C2HC domain-containing protein 1C
Search

ZC2HC1C

0.96	Zinc finger C2HC domain-containing protein 1C homolog

0.53	GO:0005515	protein binding
0.51	GO:0046872	metal ion binding

sp|Q53FE4|CD017_HUMAN
Uncharacterized protein C4orf17
Search

sp|Q53FP2|TM35A_HUMAN
Transmembrane protein 35A
Search

TMEM35A

0.97	Transmembrane protein 35

0.37

GO:0034508

centromere complex assembly

0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0032555	purine ribonucleotide binding

0.42	GO:0005778	peroxisomal membrane
0.41	GO:0031410	cytoplasmic vesicle
0.37	GO:0000776	kinetochore
0.30	GO:0031224	intrinsic component of membrane

sp|Q53FT3|HIKES_HUMAN
Protein Hikeshi
Search

HIKESHI

0.97	Hikeshi, heat shock protein nuclear import factor

0.81	GO:0034605	cellular response to heat
0.81	GO:0006606	protein import into nucleus
0.78	GO:0030324	lung development
0.77	GO:0007030	Golgi organization

0.85	GO:0030544	Hsp70 protein binding
0.71	GO:0008565	protein transporter activity

0.69	GO:0005829	cytosol
0.61	GO:0005634	nucleus

sp|Q53FV1|ORML2_HUMAN
ORM1-like protein 2
Search

ORMDL2

0.92	ORMDL sphingolipid biosynthesis regulator 2

0.82	GO:0006672	ceramide metabolic process
0.81	GO:0090155	negative regulation of sphingolipid biosynthetic process
0.71	GO:0090156	cellular sphingolipid homeostasis
0.63	GO:2000303	regulation of ceramide biosynthetic process
0.55	GO:0034249	negative regulation of cellular amide metabolic process
0.34	GO:0042176	regulation of protein catabolic process
0.33	GO:0050790	regulation of catalytic activity

0.33

GO:0030234

enzyme regulator activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.55	GO:0002178	palmitoyltransferase complex
0.33	GO:1905369	endopeptidase complex
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q53FZ2|ACSM3_HUMAN
Acyl-coenzyme A synthetase ACSM3, mitochondrial
Search

ACSM3

0.97	Acyl-CoA synthetase medium chain family member 3

0.64	GO:0006633	fatty acid biosynthetic process
0.55	GO:0006637	acyl-CoA metabolic process
0.33	GO:0055114	oxidation-reduction process

0.72	GO:0015645	fatty acid ligase activity
0.67	GO:0003996	acyl-CoA ligase activity
0.65	GO:0004321	fatty-acyl-CoA synthase activity
0.37	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen

0.69

GO:0005759

mitochondrial matrix

0.72

EC:6.2.1

GO:0015645

sp|Q53G44|IF44L_HUMAN
Interferon-induced protein 44-like
Search

0.93	Interferon-inducible microtubular aggregate protein 44

0.54	GO:0009615	response to virus
0.54	GO:0002252	immune effector process
0.53	GO:0098542	defense response to other organism
0.37	GO:0006955	immune response
0.30	GO:0008152	metabolic process

0.61	GO:0032550	purine ribonucleoside binding
0.61	GO:0019001	guanyl nucleotide binding
0.51	GO:0032553	ribonucleotide binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q53G59|KLH12_HUMAN
Kelch-like protein 12
Search

KLHL12

0.89	Kelch like family member 12

0.83	GO:0048208	COPII vesicle coating
0.82	GO:0014029	neural crest formation
0.81	GO:0006513	protein monoubiquitination
0.79	GO:0014032	neural crest cell development
0.71	GO:0016055	Wnt signaling pathway
0.40	GO:0060028	convergent extension involved in axis elongation
0.39	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.38	GO:0009952	anterior/posterior pattern specification
0.37	GO:0007264	small GTPase mediated signal transduction
0.36	GO:0065009	regulation of molecular function

0.67	GO:0042802	identical protein binding
0.59	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0031463	Cul3-RING ubiquitin ligase complex
0.77	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.73	GO:0030658	transport vesicle membrane
0.72	GO:0000139	Golgi membrane
0.72	GO:0030120	vesicle coat
0.72	GO:0030660	Golgi-associated vesicle membrane
0.68	GO:0005815	microtubule organizing center
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.59

GO:0004842

sp|Q53GA4|PHLA2_HUMAN
Pleckstrin homology-like domain family A member 2
Search

PHLDA2

0.97	Pleckstrin homology like domain family A member 2

0.85	GO:1903547	regulation of growth hormone activity
0.85	GO:0060721	regulation of spongiotrophoblast cell proliferation
0.79	GO:0070873	regulation of glycogen metabolic process
0.74	GO:0001890	placenta development
0.71	GO:0030334	regulation of cell migration
0.70	GO:0009887	animal organ morphogenesis
0.52	GO:0010468	regulation of gene expression
0.47	GO:0006915	apoptotic process
0.45	GO:0051898	negative regulation of protein kinase B signaling
0.44	GO:0072331	signal transduction by p53 class mediator

0.45	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.45	GO:0010314	phosphatidylinositol-5-phosphate binding
0.45	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.44	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.44	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.44	GO:0032266	phosphatidylinositol-3-phosphate binding
0.35	GO:0031177	phosphopantetheine binding
0.34	GO:0004312	fatty acid synthase activity

0.40	GO:0005737	cytoplasm
0.37	GO:0005730	nucleolus
0.37	GO:0015629	actin cytoskeleton
0.37	GO:0005886	plasma membrane
0.37	GO:0099512	supramolecular fiber
0.36	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.3.1.85

GO:0004312

sp|Q53GD3|CTL4_HUMAN
Choline transporter-like protein 4
Search

SLC44A4

0.90	Testicular tissue protein Li 48

0.62	GO:0061526	acetylcholine secretion
0.61	GO:0008292	acetylcholine biosynthetic process
0.61	GO:0030974	thiamine pyrophosphate transmembrane transport
0.57	GO:0030307	positive regulation of cell growth
0.56	GO:0015871	choline transport
0.45	GO:0032475	otolith formation
0.45	GO:0035675	neuromast hair cell development
0.37	GO:0006656	phosphatidylcholine biosynthetic process
0.35	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.34	GO:0043312	neutrophil degranulation

0.62	GO:0090422	thiamine pyrophosphate transmembrane transporter activity
0.58	GO:0015220	choline transmembrane transporter activity
0.34	GO:0004871	signal transducer activity
0.33	GO:0005515	protein binding

0.56	GO:0016324	apical plasma membrane
0.39	GO:0070062	extracellular exosome
0.35	GO:0005765	lysosomal membrane
0.35	GO:0035579	specific granule membrane
0.30	GO:0016021	integral component of membrane

sp|Q53GG5|PDLI3_HUMAN
PDZ and LIM domain protein 3
Search

PDLIM3

0.96	PDZ and LIM domain protein 3

0.57	GO:0007507	heart development
0.54	GO:0007015	actin filament organization
0.36	GO:0007519	skeletal muscle tissue development

0.61	GO:0008307	structural constituent of muscle
0.53	GO:0046872	metal ion binding
0.52	GO:0008092	cytoskeletal protein binding

0.54	GO:0015629	actin cytoskeleton
0.42	GO:0030018	Z disc

sp|Q53GI3|ZN394_HUMAN
Zinc finger protein 394
Search

0.67	Zinc finger protein with KRAB and SCAN domains 8

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.36	GO:0015074	DNA integration
0.33	GO:0006468	protein phosphorylation

0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0046872	metal ion binding
0.49	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q53GL0|PKHO1_HUMAN
Pleckstrin homology domain-containing family O member 1
Search

PLEKHO1

0.97	Pleckstrin like proteiny domain-containing family O member 1

0.84	GO:0072673	lamellipodium morphogenesis
0.83	GO:0051451	myoblast migration
0.80	GO:0007520	myoblast fusion
0.66	GO:0022603	regulation of anatomical structure morphogenesis
0.63	GO:0051128	regulation of cellular component organization
0.59	GO:0065008	regulation of biological quality
0.49	GO:0010830	regulation of myotube differentiation
0.42	GO:0006904	vesicle docking involved in exocytosis

0.38

GO:0005515

protein binding

0.85	GO:0036195	muscle cell projection membrane
0.79	GO:0032587	ruffle membrane
0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q53GL7|PAR10_HUMAN
Poly [ADP-ribose] polymerase 10
Search

PARP10

0.46	Poly [ADP-ribose] polymerase

0.52	GO:0033159	negative regulation of protein import into nucleus, translocation
0.51	GO:0070213	protein auto-ADP-ribosylation
0.51	GO:0070212	protein poly-ADP-ribosylation
0.51	GO:1900045	negative regulation of protein K63-linked ubiquitination
0.50	GO:0048147	negative regulation of fibroblast proliferation
0.50	GO:0010847	regulation of chromatin assembly
0.49	GO:0045071	negative regulation of viral genome replication
0.49	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.43	GO:0010629	negative regulation of gene expression
0.33	GO:0007015	actin filament organization

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.49	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.35	GO:0003676	nucleic acid binding
0.34	GO:0008270	zinc ion binding
0.32	GO:0016491	oxidoreductase activity

0.57	GO:0005730	nucleolus
0.54	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0003950

sp|Q53GQ0|DHB12_HUMAN
Very-long-chain 3-oxoacyl-CoA reductase
Search

HSD17B12

0.71	Very-long-chain 3-oxoacyl-CoA reductase-B

0.52	GO:0010811	positive regulation of cell-substrate adhesion
0.51	GO:0055114	oxidation-reduction process
0.50	GO:0030198	extracellular matrix organization
0.46	GO:0042446	hormone biosynthetic process
0.46	GO:0006694	steroid biosynthetic process
0.45	GO:0008210	estrogen metabolic process
0.42	GO:0030539	male genitalia development
0.40	GO:0006633	fatty acid biosynthetic process
0.39	GO:1901617	organic hydroxy compound biosynthetic process
0.39	GO:0042181	ketone biosynthetic process

0.54	GO:0001968	fibronectin binding
0.52	GO:0016491	oxidoreductase activity
0.51	GO:0005518	collagen binding
0.51	GO:0008201	heparin binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.32	GO:0005840	ribosome
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.52

GO:0016491

sp|Q53GS7|GLE1_HUMAN
Nucleoporin GLE1
Search

GLE1

0.88	Putative nuclear-export-signal nes-containing protein/polyadenylated-rna export factor

0.84	GO:0016973	poly(A)+ mRNA export from nucleus
0.54	GO:0006449	regulation of translational termination
0.53	GO:0006446	regulation of translational initiation

0.61	GO:0042802	identical protein binding
0.59	GO:0000822	inositol hexakisphosphate binding
0.55	GO:0031369	translation initiation factor binding
0.52	GO:0005543	phospholipid binding

0.78	GO:0005643	nuclear pore
0.65	GO:0031965	nuclear membrane
0.60	GO:0005730	nucleolus
0.57	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q53GS9|SNUT2_HUMAN
U4/U6.U5 tri-snRNP-associated protein 2
Search

USP39

0.90	Ubiquitin carboxyl-terminal hydrolase 3

0.82	GO:0000245	spliceosomal complex assembly
0.76	GO:0016579	protein deubiquitination
0.59	GO:0048855	adenohypophysis morphogenesis
0.54	GO:1904888	cranial skeletal system development
0.53	GO:0043484	regulation of RNA splicing

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.62	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.55

GO:0005654

nucleoplasm

0.77

GO:0036459

sp|Q53GT1|KLH22_HUMAN
Kelch-like protein 22
Search

KLHL22

0.87	Scavenger receptor class F member 2

0.72	GO:0016567	protein ubiquitination
0.66	GO:0051301	cell division
0.60	GO:0007094	mitotic spindle assembly checkpoint
0.56	GO:0000070	mitotic sister chromatid segregation
0.35	GO:0043687	post-translational protein modification
0.34	GO:2000042	negative regulation of double-strand break repair via homologous recombination
0.34	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system
0.33	GO:0045454	cell redox homeostasis
0.32	GO:0006260	DNA replication
0.32	GO:0009409	response to cold

0.48	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0005515	protein binding
0.33	GO:0061731	ribonucleoside-diphosphate reductase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003677	DNA binding

0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.65	GO:0005827	polar microtubule
0.59	GO:0072686	mitotic spindle
0.57	GO:0005813	centrosome
0.41	GO:0005737	cytoplasm
0.32	GO:0005634	nucleus

0.48

GO:0004842

sp|Q53H12|AGK_HUMAN
Acylglycerol kinase, mitochondrial
Search

AGK

0.95	Acylglycerol kinase, mitochondrial

0.62	GO:0045039	protein import into mitochondrial inner membrane
0.61	GO:0046513	ceramide biosynthetic process
0.56	GO:0016310	phosphorylation
0.53	GO:0030258	lipid modification
0.39	GO:0046486	glycerolipid metabolic process
0.34	GO:0008654	phospholipid biosynthetic process

0.74	GO:0003951	NAD+ kinase activity
0.64	GO:0001729	ceramide kinase activity
0.46	GO:0047620	acylglycerol kinase activity
0.41	GO:0004143	diacylglycerol kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0042721	mitochondrial inner membrane protein insertion complex
0.60	GO:0031305	integral component of mitochondrial inner membrane
0.59	GO:0005758	mitochondrial intermembrane space
0.35	GO:0005741	mitochondrial outer membrane
0.34	GO:0005829	cytosol

0.74	EC:2.7.1.23	GO:0003951
0.74	KEGG:R00104	GO:0003951

sp|Q53H47|SETMR_HUMAN
Histone-lysine N-methyltransferase SETMAR
Search

SETMAR

0.49	SET domain and mariner transposase fusion gene

0.70	GO:0034968	histone lysine methylation
0.50	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
0.49	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining
0.48	GO:0071157	negative regulation of cell cycle arrest
0.48	GO:0000729	DNA double-strand break processing
0.48	GO:0018027	peptidyl-lysine dimethylation
0.47	GO:0031297	replication fork processing
0.47	GO:0044774	mitotic DNA integrity checkpoint
0.47	GO:0000737	DNA catabolic process, endonucleolytic
0.46	GO:0006303	double-strand break repair via nonhomologous end joining

0.70	GO:0018024	histone-lysine N-methyltransferase activity
0.57	GO:0008270	zinc ion binding
0.50	GO:0044547	DNA topoisomerase binding
0.47	GO:0000014	single-stranded DNA endodeoxyribonuclease activity
0.44	GO:0042803	protein homodimerization activity
0.44	GO:0003697	single-stranded DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004722	protein serine/threonine phosphatase activity

0.60	GO:0005694	chromosome
0.56	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.70

EC:2.1.1.43

GO:0018024

sp|Q53H54|TYW2_HUMAN
tRNA wybutosine-synthesizing protein 2 homolog
Search

TRMT12

0.81	tRNA wybutosine-synthesizing protein 2

0.62	GO:0008033	tRNA processing
0.37	GO:0032259	methylation

0.51	GO:0016740	transferase activity
0.41	GO:0140101	catalytic activity, acting on a tRNA
0.35	GO:0005515	protein binding

0.30

GO:0031224

intrinsic component of membrane

0.51

GO:0016740

sp|Q53H64|CQ073_HUMAN
Putative uncharacterized protein encoded by LINC00483
Search

sp|Q53H76|PLA1A_HUMAN
Phospholipase A1 member A
Search

PLA1A

0.96	Phospholipase A1 member A

0.62	GO:0006629	lipid metabolic process
0.39	GO:1901575	organic substance catabolic process
0.34	GO:0006575	cellular modified amino acid metabolic process
0.33	GO:0019637	organophosphate metabolic process
0.33	GO:0006796	phosphate-containing compound metabolic process
0.32	GO:0035556	intracellular signal transduction

0.70	GO:0052689	carboxylic ester hydrolase activity
0.53	GO:0016298	lipase activity
0.34	GO:0008201	heparin binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0008081	phosphoric diester hydrolase activity

0.66	GO:0005576	extracellular region
0.57	GO:0002080	acrosomal membrane
0.30	GO:0016021	integral component of membrane

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

sp|Q53H80|AKIR2_HUMAN
Akirin-2
Search

AKIRIN2

0.93	Capra hircus Akirin 2 mRNA

0.80	GO:0032755	positive regulation of interleukin-6 production
0.77	GO:0032496	response to lipopolysaccharide
0.73	GO:0009792	embryo development ending in birth or egg hatching
0.70	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0045087	innate immune response
0.46	GO:0010950	positive regulation of endopeptidase activity
0.45	GO:0008284	positive regulation of cell proliferation
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0006351	transcription, DNA-templated
0.37	GO:0006420	arginyl-tRNA aminoacylation

0.68	GO:0019899	enzyme binding
0.37	GO:0004814	arginine-tRNA ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0005654	nucleoplasm
0.48	GO:0017053	transcriptional repressor complex
0.30	GO:0016020	membrane

0.37

EC:6.1.1.19

GO:0004814

sp|Q53H82|LACB2_HUMAN
Endoribonuclease LACTB2
Search

LACTB2

0.92	Lactamase beta 2

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.39	GO:0017001	antibiotic catabolic process

0.79	GO:0003727	single-stranded RNA binding
0.70	GO:0004521	endoribonuclease activity
0.63	GO:0008270	zinc ion binding
0.39	GO:0008800	beta-lactamase activity

0.75

GO:0005759

mitochondrial matrix

0.39

EC:3.5.2.6

GO:0008800

sp|Q53H96|P5CR3_HUMAN
Pyrroline-5-carboxylate reductase 3
Search

PYCR3

0.50	Pyrroline-5-carboxylate reductase

0.75	GO:0006561	proline biosynthetic process
0.55	GO:0017144	drug metabolic process
0.52	GO:0055114	oxidation-reduction process
0.35	GO:0009972	cytidine deamination
0.32	GO:0006508	proteolysis

0.78	GO:0004735	pyrroline-5-carboxylate reductase activity
0.51	GO:0042802	identical protein binding
0.35	GO:0004126	cytidine deaminase activity
0.34	GO:0016920	pyroglutamyl-peptidase activity

0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78

EC:1.5.1.2

GO:0004735

sp|Q53HC0|CCD92_HUMAN
Coiled-coil domain-containing protein 92
Search

CCDC92

0.97	Coiled-coil domain-containing protein 92

0.36

GO:0005515

protein binding

0.82	GO:0005814	centriole
0.75	GO:0005813	centrosome
0.68	GO:0005654	nucleoplasm

sp|Q53HC5|KLH26_HUMAN
Kelch-like protein 26
Search

KLHL26

0.97	Kelch like family member 26

0.84	GO:0008584	male gonad development
0.83	GO:0007286	spermatid development
0.82	GO:0009566	fertilization
0.73	GO:0016567	protein ubiquitination

0.74

GO:0004842

ubiquitin-protein transferase activity

0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.49	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0004842

sp|Q53HC9|TSSC1_HUMAN
Protein TSSC1
Search

EIPR1

0.94	EARP complex and GARP complex interacting protein 1

sp|Q53HI1|UNC50_HUMAN
Protein unc-50 homolog
Search

UNC50

0.97	Unc-50 inner nuclear membrane RNA binding protein (Fragment)

0.65	GO:0005794	Golgi apparatus
0.50	GO:0031301	integral component of organelle membrane
0.48	GO:0098588	bounding membrane of organelle
0.47	GO:0031984	organelle subcompartment

sp|Q53HL2|BOREA_HUMAN
Borealin
Search

CDCA8

0.95	Cell division cycle associated 8

0.82	GO:0007080	mitotic metaphase plate congression
0.41	GO:0051301	cell division

0.84	GO:0032133	chromosome passenger complex
0.83	GO:0010369	chromocenter
0.82	GO:0045171	intercellular bridge
0.80	GO:0030496	midbody
0.74	GO:0000775	chromosome, centromeric region
0.70	GO:0005730	nucleolus
0.57	GO:0051233	spindle midzone
0.30	GO:0031224	intrinsic component of membrane

sp|Q53HV7|SMUG1_HUMAN
Single-strand selective monofunctional uracil DNA glycosylase
Search

SMUG1

0.96	Single-strand selective monofunctional uracil DNA glycosylase

0.57	GO:0006284	base-excision repair
0.39	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.36	GO:0006304	DNA modification

0.73	GO:0017065	single-strand selective uracil DNA N-glycosylase activity
0.59	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
0.48	GO:0003677	DNA binding
0.37	GO:0004807	triose-phosphate isomerase activity
0.35	GO:0005515	protein binding

0.57	GO:0005730	nucleolus
0.36	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.73	EC:3.2.2	GO:0017065
0.37	KEGG:R01015	GO:0004807

sp|Q53LP3|SWAHC_HUMAN
Ankyrin repeat domain-containing protein SOWAHC
Search

SOWAHC

0.94	Ankyrin repeat domain-containing protein SOWAHC

0.42	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.41	GO:0070941	eisosome assembly
0.40	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.43	GO:0000213	tRNA-intron endonuclease activity
0.35	GO:0003676	nucleic acid binding

0.41	GO:0032126	eisosome
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:3.1.27.9

GO:0000213

sp|Q53QV2|LBH_HUMAN
Protein LBH
Search

LBH

0.95	Limb bud and heart development

0.57	GO:1904677	positive regulation of somatic stem cell division
0.57	GO:2000101	regulation of mammary stem cell proliferation
0.57	GO:1904674	positive regulation of somatic stem cell population maintenance
0.55	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.54	GO:2000737	negative regulation of stem cell differentiation
0.52	GO:0060644	mammary gland epithelial cell differentiation
0.50	GO:0008284	positive regulation of cell proliferation

0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q53QW1|TEX44_HUMAN
Testis-expressed protein 44
Search

TEX44

0.97	Testis-expressed protein 44

0.45

GO:0005515

protein binding

0.49

GO:0005737

cytoplasm

sp|Q53QZ3|RHG15_HUMAN
Rho GTPase-activating protein 15
Search

ARHGAP15

0.97	LOW QUALITY PROTEIN: rho GTPase-activating protein 15

0.69	GO:0043547	positive regulation of GTPase activity
0.59	GO:0007165	signal transduction
0.50	GO:0008360	regulation of cell shape
0.42	GO:0006911	phagocytosis, engulfment
0.41	GO:0051058	negative regulation of small GTPase mediated signal transduction
0.41	GO:0002011	morphogenesis of an epithelial sheet
0.39	GO:0007015	actin filament organization

0.69	GO:0005096	GTPase activator activity
0.44	GO:0005543	phospholipid binding

0.42	GO:0001891	phagocytic cup
0.34	GO:0005737	cytoplasm

sp|Q53R12|T4S20_HUMAN
Transmembrane 4 L6 family member 20
Search

TM4SF20

0.97	Transmembrane 4 L six family member 20

0.69

GO:0045861

negative regulation of proteolysis

0.73	GO:0005925	focal adhesion
0.65	GO:0005789	endoplasmic reticulum membrane
0.51	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q53R41|FAKD1_HUMAN
FAST kinase domain-containing protein 1, mitochondrial
Search

FASTKD1

0.97	FAST kinase domain-containing protein 1

0.64	GO:0044528	regulation of mitochondrial mRNA stability
0.62	GO:0006468	protein phosphorylation
0.59	GO:0000959	mitochondrial RNA metabolic process
0.36	GO:0045333	cellular respiration

0.62	GO:0004672	protein kinase activity
0.35	GO:0003723	RNA binding

0.47	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q53RD9|FBLN7_HUMAN
Fibulin-7
Search

FBLN7

0.97

Fibulin-7

0.36	GO:0007155	cell adhesion
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.32	GO:0030198	extracellular matrix organization
0.32	GO:0007219	Notch signaling pathway
0.32	GO:0010466	negative regulation of peptidase activity

0.70	GO:0005509	calcium ion binding
0.38	GO:0008201	heparin binding
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005201	extracellular matrix structural constituent
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005112	Notch binding
0.32	GO:0003677	DNA binding
0.32	GO:0030414	peptidase inhibitor activity

0.38	GO:0044421	extracellular region part
0.38	GO:0005925	focal adhesion
0.36	GO:0031982	vesicle
0.30	GO:0016020	membrane

0.35

GO:0004713

sp|Q53RE8|ANR39_HUMAN
Ankyrin repeat domain-containing protein 39
Search

ANKRD39

0.97	Ankyrin repeat domain-containing protein 39

0.40	GO:0006471	protein ADP-ribosylation
0.40	GO:0009116	nucleoside metabolic process
0.38	GO:0006508	proteolysis
0.38	GO:0007219	Notch signaling pathway
0.36	GO:0070682	proteasome regulatory particle assembly
0.36	GO:0030154	cell differentiation
0.36	GO:0050793	regulation of developmental process
0.35	GO:0034220	ion transmembrane transport
0.35	GO:0035556	intracellular signal transduction
0.34	GO:0016310	phosphorylation

0.47	GO:0031432	titin binding
0.40	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.38	GO:0004175	endopeptidase activity
0.37	GO:0005216	ion channel activity
0.37	GO:0070001	aspartic-type peptidase activity
0.36	GO:0017171	serine hydrolase activity
0.34	GO:0016301	kinase activity
0.34	GO:0003723	RNA binding

0.49	GO:1905369	endopeptidase complex
0.43	GO:0043234	protein complex
0.37	GO:0005622	intracellular
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.40

GO:0003950

sp|Q53RT3|APRV1_HUMAN
Retroviral-like aspartic protease 1
Search

ASPRV1

0.97	Aspartic peptidase retroviral like 1

0.68	GO:0043588	skin development
0.63	GO:0016485	protein processing

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

sp|Q53RY4|KCP3_HUMAN
Keratinocyte-associated protein 3
Search

KRTCAP3

0.66	Keratinocyte-associated protein 3

0.35	GO:0006464	cellular protein modification process
0.34	GO:0016310	phosphorylation

0.35	GO:0004672	protein kinase activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016874	ligase activity
0.32	GO:0046872	metal ion binding

0.33	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:6	GO:0016874
0.34	KEGG:R03876	GO:0004842

tr|Q53S08|Q53S08_HUMAN
Putative uncharacterized protein RAB6C
Search

RAB6A

0.91	Ras-related protein Rab-6A isoform a

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.38

GO:0005794

Golgi apparatus

sp|Q53S33|BOLA3_HUMAN
BolA-like protein 3
Search

BOLA3

0.97	BolA protein 3

0.39	GO:1902600	hydrogen ion transmembrane transport
0.39	GO:0022900	electron transport chain
0.38	GO:0036086	positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation
0.38	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.38	GO:0051220	cytoplasmic sequestering of protein
0.38	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.37	GO:0006879	cellular iron ion homeostasis
0.36	GO:0034396	negative regulation of transcription from RNA polymerase II promoter in response to iron
0.35	GO:0016310	phosphorylation

0.40	GO:0015002	heme-copper terminal oxidase activity
0.40	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.39	GO:0015078	hydrogen ion transmembrane transporter activity
0.39	GO:0009055	electron transfer activity
0.36	GO:0051213	dioxygenase activity
0.36	GO:0051537	2 iron, 2 sulfur cluster binding
0.35	GO:0016301	kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0032555	purine ribonucleotide binding

0.57	GO:0005739	mitochondrion
0.37	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40

EC:1.9.3

GO:0016676

tr|Q53S48|Q53S48_HUMAN
Putative uncharacterized protein ALF
Search

STON1

0.95	TFIIA-alpha and beta-like factor

0.75	GO:0030100	regulation of endocytosis
0.67	GO:0006897	endocytosis
0.66	GO:0006367	transcription initiation from RNA polymerase II promoter
0.38	GO:0015031	protein transport
0.37	GO:0046907	intracellular transport
0.37	GO:0034613	cellular protein localization
0.37	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:0050890	cognition
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.43	GO:0003713	transcription coactivator activity
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.69	GO:0005672	transcription factor TFIIA complex
0.39	GO:0030131	clathrin adaptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q53S58|TM177_HUMAN
Transmembrane protein 177
Search

TMEM177

0.93	Transmembrane domain-containing protein (Fragment)

0.36

GO:0005515

protein binding

0.61

GO:0031305

integral component of mitochondrial inner membrane

sp|Q53S99|CB083_HUMAN
Folate transporter-like protein C2orf83
Search

sp|Q53SF7|COBL1_HUMAN
Cordon-bleu protein-like 1
Search

COBLL1

0.96	Cordon-bleu WH2 repeat protein like 1

0.68	GO:0051639	actin filament network formation
0.64	GO:0030041	actin filament polymerization
0.37	GO:0007165	signal transduction
0.36	GO:0030097	hemopoiesis

0.72	GO:0003779	actin binding
0.42	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0045296	cadherin binding

0.36	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q53SZ7|PRR30_HUMAN
Proline-rich protein 30
Search

sp|Q53T59|H1BP3_HUMAN
HCLS1-binding protein 3
Search

HS1BP3

0.97	HCLS1-binding protein 3

0.55	GO:0042981	regulation of apoptotic process
0.36	GO:0030217	T cell differentiation
0.35	GO:0007166	cell surface receptor signaling pathway

0.75	GO:0035091	phosphatidylinositol binding
0.34	GO:0005515	protein binding

0.52	GO:0005783	endoplasmic reticulum
0.47	GO:0005739	mitochondrion

sp|Q53T94|TAF1B_HUMAN
TATA box-binding protein-associated factor RNA polymerase I subunit B
Search

TAF1B

0.97	TATA box-binding protein-associated factor RNA polymerase I subunit B

0.85	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.38	GO:0006362	transcription elongation from RNA polymerase I promoter
0.37	GO:0006363	termination of RNA polymerase I transcription
0.35	GO:0010604	positive regulation of macromolecule metabolic process

0.85	GO:0001187	RNA polymerase I CORE element sequence-specific DNA binding
0.37	GO:0046872	metal ion binding
0.37	GO:0017025	TBP-class protein binding
0.34	GO:0003700	DNA binding transcription factor activity

0.85	GO:0070860	RNA polymerase I core factor complex
0.55	GO:0005668	RNA polymerase transcription factor SL1 complex
0.39	GO:0070062	extracellular exosome
0.37	GO:0005654	nucleoplasm

sp|Q53TN4|CYBR1_HUMAN
Cytochrome b reductase 1
Search

CYBRD1

0.96	Cytochrome b reductase 1

0.81	GO:0010039	response to iron ion
0.53	GO:0055114	oxidation-reduction process
0.35	GO:0006879	cellular iron ion homeostasis
0.33	GO:0007018	microtubule-based movement

0.83	GO:0000293	ferric-chelate reductase activity
0.40	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.82	GO:0031526	brush border membrane
0.55	GO:0005765	lysosomal membrane
0.49	GO:0031902	late endosome membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0005868	cytoplasmic dynein complex
0.33	GO:0005813	centrosome
0.33	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.83

EC:1.16.1.7

GO:0000293

sp|Q53TQ3|IN80D_HUMAN
INO80 complex subunit D
Search

INO80D

0.95	INO80 complex subunit Da

0.48	GO:0006310	DNA recombination
0.48	GO:0006281	DNA repair
0.44	GO:0016579	protein deubiquitination
0.44	GO:0006351	transcription, DNA-templated
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part

sp|Q53TS8|AL2SA_HUMAN
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein
Search

C2CD6

0.86	C2 calcium-dependent domain-containing protein 6

0.59

GO:0005515

protein binding

sp|Q562E7|WDR81_HUMAN
WD repeat-containing protein 81
Search

WDR81

0.90	WD repeat-containing protein 81

0.87	GO:0035973	aggrephagy
0.86	GO:0045022	early endosome to late endosome transport
0.85	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.82	GO:0010923	negative regulation of phosphatase activity
0.80	GO:0050821	protein stabilization
0.74	GO:0007005	mitochondrion organization
0.73	GO:0006511	ubiquitin-dependent protein catabolic process

0.85	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.85	GO:0035014	phosphatidylinositol 3-kinase regulator activity

0.86	GO:0031313	extrinsic component of endosome membrane
0.85	GO:0000421	autophagosome membrane
0.85	GO:0031901	early endosome membrane
0.83	GO:0031902	late endosome membrane
0.82	GO:0005765	lysosomal membrane
0.69	GO:0005829	cytosol
0.61	GO:0005739	mitochondrion
0.45	GO:0005789	endoplasmic reticulum membrane
0.45	GO:0005794	Golgi apparatus

sp|Q562F6|SGO2_HUMAN
Shugoshin 2
Search

SGO2

0.73	Shugoshin 2

0.86	GO:0051754	meiotic sister chromatid cohesion, centromeric
0.30	GO:0051301	cell division

0.30

GO:0005515

protein binding

0.77	GO:0000775	chromosome, centromeric region
0.68	GO:0030892	mitotic cohesin complex
0.63	GO:0016604	nuclear body
0.30	GO:0005737	cytoplasm

sp|Q562R1|ACTBL_HUMAN
Beta-actin-like protein 2
Search

0.61	Skeletal muscle actin

0.64	GO:0090131	mesenchyme migration
0.53	GO:0010628	positive regulation of gene expression
0.48	GO:0030240	skeletal muscle thin filament assembly
0.47	GO:0033275	actin-myosin filament sliding
0.47	GO:0072359	circulatory system development
0.47	GO:0060047	heart contraction
0.46	GO:0060415	muscle tissue morphogenesis
0.45	GO:0014706	striated muscle tissue development
0.44	GO:0043066	negative regulation of apoptotic process
0.42	GO:0072143	mesangial cell development

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0017022	myosin binding
0.39	GO:0016887	ATPase activity
0.35	GO:0019901	protein kinase binding

0.60	GO:0030175	filopodium
0.59	GO:0030027	lamellipodium
0.58	GO:0044297	cell body
0.48	GO:0042643	actomyosin, actin portion
0.46	GO:0044449	contractile fiber part
0.45	GO:0030016	myofibril
0.39	GO:0070062	extracellular exosome
0.36	GO:0072562	blood microparticle
0.36	GO:0001725	stress fiber
0.36	GO:0005925	focal adhesion

0.39

GO:0016887

sp|Q567U6|CCD93_HUMAN
Coiled-coil domain-containing protein 93
Search

CCDC93

0.96	Coiled-coil domain-containing protein 93

0.82	GO:0006893	Golgi to plasma membrane transport
0.44	GO:0015031	protein transport

0.36

GO:0005515

protein binding

0.54	GO:0043227	membrane-bounded organelle
0.51	GO:0043229	intracellular organelle
0.45	GO:0012505	endomembrane system
0.40	GO:0044444	cytoplasmic part

sp|Q567V2|M17L2_HUMAN
Mpv17-like protein 2
Search

MPV17L2

0.97	MPV17 mitochondrial inner membrane protein like 2

0.64	GO:0061668	mitochondrial ribosome assembly
0.59	GO:0070131	positive regulation of mitochondrial translation
0.33	GO:0034614	cellular response to reactive oxygen species

0.56	GO:0005762	mitochondrial large ribosomal subunit
0.47	GO:0031966	mitochondrial membrane
0.47	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q569G3|CE047_HUMAN
Uncharacterized protein C5orf47
Search

sp|Q569H4|LARGN_HUMAN
Protein Largen
Search

PRR16

0.97	Proline-rich protein 16

0.86	GO:0045793	positive regulation of cell size
0.78	GO:0045727	positive regulation of translation

sp|Q569K4|Z385B_HUMAN
Zinc finger protein 385B
Search

ZNF385B

0.96	Zinc finger protein 385B isoform A

0.58

GO:0072332

intrinsic apoptotic signaling pathway by p53 class mediator

0.62	GO:0008270	zinc ion binding
0.58	GO:0002039	p53 binding
0.50	GO:0003676	nucleic acid binding

0.56	GO:0001650	fibrillar center
0.30	GO:0031224	intrinsic component of membrane

sp|Q569K6|CC157_HUMAN
Coiled-coil domain-containing protein 157
Search

CCDC157

0.85	Coiled-coil domain-containing protein 157

0.49

GO:0003676

nucleic acid binding

sp|Q56A73|SPIN4_HUMAN
Spindlin-4
Search

SPIN4

0.97	Z-linked spindlin 1

0.78	GO:0007276	gamete generation
0.47	GO:0009303	rRNA transcription
0.46	GO:0030177	positive regulation of Wnt signaling pathway
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0051321	meiotic cell cycle
0.37	GO:0016055	Wnt signaling pathway
0.36	GO:0016569	covalent chromatin modification
0.36	GO:0007275	multicellular organism development
0.34	GO:0046294	formaldehyde catabolic process
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism

0.59	GO:0140034	methylation-dependent protein binding
0.57	GO:0042393	histone binding
0.34	GO:0018738	S-formylglutathione hydrolase activity
0.33	GO:0003677	DNA binding
0.33	GO:0052689	carboxylic ester hydrolase activity

0.45	GO:0031965	nuclear membrane
0.44	GO:0005819	spindle
0.43	GO:0005730	nucleolus
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:3.1.2.12	GO:0018738
0.34	KEGG:R00527	GO:0018738

sp|Q56NI9|ESCO2_HUMAN
N-acetyltransferase ESCO2
Search

ESCO2

0.95	Establishment of sister chromatid cohesion N-acetyltransferase 2

0.79	GO:0034421	post-translational protein acetylation
0.68	GO:0006275	regulation of DNA replication
0.66	GO:0071168	protein localization to chromatin
0.65	GO:0007059	chromosome segregation
0.64	GO:0002244	hematopoietic progenitor cell differentiation
0.58	GO:0006302	double-strand break repair
0.52	GO:0022402	cell cycle process
0.50	GO:0051276	chromosome organization
0.44	GO:0018394	peptidyl-lysine acetylation
0.42	GO:1990523	bone regeneration

0.68	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
0.45	GO:0061733	peptide-lysine-N-acetyltransferase activity
0.40	GO:0008270	zinc ion binding
0.35	GO:0005044	scavenger receptor activity
0.33	GO:0042802	identical protein binding

0.66	GO:0001741	XY body
0.65	GO:0010369	chromocenter
0.64	GO:0031618	nuclear pericentric heterochromatin
0.63	GO:0035861	site of double-strand break
0.57	GO:0030054	cell junction
0.55	GO:0005794	Golgi apparatus
0.36	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.68

EC:2.3.1.32

GO:0004468

sp|Q56P03|EAPP_HUMAN
E2F-associated phosphoprotein
Search

EAPP

0.96	E2F-associated phosphoprotein isoform X2

0.84	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.78	GO:0008284	positive regulation of cell proliferation
0.77	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.33	GO:0006468	protein phosphorylation
0.33	GO:0055114	oxidation-reduction process

0.33	GO:0004672	protein kinase activity
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0016491

sp|Q56P42|PYDC2_HUMAN
Pyrin domain-containing protein 2
Search

0.80	Pyrin domain-containing protein 2

0.72	GO:0050706	regulation of interleukin-1 beta secretion
0.70	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.62	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly
0.61	GO:0050711	negative regulation of interleukin-1 secretion
0.61	GO:0050716	positive regulation of interleukin-1 secretion
0.60	GO:0032731	positive regulation of interleukin-1 beta production
0.60	GO:0032691	negative regulation of interleukin-1 beta production
0.60	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.58	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.58	GO:0042347	negative regulation of NF-kappaB import into nucleus

0.64	GO:0032090	Pyrin domain binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0000784	nuclear chromosome, telomeric region
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005829	cytosol

sp|Q56UN5|M3K19_HUMAN
Mitogen-activated protein kinase kinase kinase 19
Search

MAP3K19

0.95	Mitogen-activated protein kinase kinase kinase 19

0.63	GO:0006468	protein phosphorylation
0.52	GO:0031098	stress-activated protein kinase signaling cascade
0.50	GO:0032147	activation of protein kinase activity
0.49	GO:0007346	regulation of mitotic cell cycle
0.48	GO:0042981	regulation of apoptotic process
0.35	GO:0043622	cortical microtubule organization
0.33	GO:0043406	positive regulation of MAP kinase activity
0.33	GO:2000071	regulation of defense response by callose deposition
0.33	GO:0099120	socially cooperative development
0.33	GO:0071323	cellular response to chitin

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.33	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.33	GO:0004623	phospholipase A2 activity
0.32	GO:0005057	signal transducer activity, downstream of receptor

0.38	GO:0005737	cytoplasm
0.35	GO:0048046	apoplast
0.32	GO:0005874	microtubule
0.32	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.33

EC:1.3.1.74

GO:0032440

sp|Q56UQ5|TPT1L_HUMAN
TPT1-like protein
Search

TPT1

0.73	Translationally-controlled tumor

0.69	GO:2000384	negative regulation of ectoderm development
0.62	GO:0019827	stem cell population maintenance
0.58	GO:0030154	cell differentiation
0.46	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.41	GO:0007283	spermatogenesis
0.41	GO:0009615	response to virus
0.40	GO:1903575	cornified envelope assembly
0.38	GO:0006874	cellular calcium ion homeostasis
0.38	GO:0008283	cell proliferation
0.38	GO:0006816	calcium ion transport

0.59	GO:0008017	microtubule binding
0.58	GO:0005509	calcium ion binding
0.56	GO:0008134	transcription factor binding
0.38	GO:0003723	RNA binding
0.37	GO:0051082	unfolded protein binding
0.35	GO:0008270	zinc ion binding

0.61	GO:0005615	extracellular space
0.57	GO:0045298	tubulin complex
0.57	GO:0005829	cytosol
0.55	GO:0005771	multivesicular body
0.54	GO:0005654	nucleoplasm
0.45	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

sp|Q56VL3|OCAD2_HUMAN
OCIA domain-containing protein 2
Search

OCIAD2

0.97	LOW QUALITY PROTEIN: OCIA domain-containing protein 2

0.36

GO:2000736

regulation of stem cell differentiation

0.58	GO:0031966	mitochondrial membrane
0.58	GO:0019866	organelle inner membrane
0.46	GO:0005768	endosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q57Z89|Q57Z89_HUMAN
HCG1732469
Search

sp|Q580R0|CB027_HUMAN
Uncharacterized protein C2orf27
Search

sp|Q587I9|SFT2C_HUMAN
Vesicle transport protein SFT2C
Search

SFT2D3

0.66	Vesicle transport protein (Fragment)

0.69	GO:0016192	vesicle-mediated transport
0.65	GO:0015031	protein transport

0.30

GO:0044425

membrane part

sp|Q587J7|TDR12_HUMAN
Putative ATP-dependent RNA helicase TDRD12
Search

TDRD12

0.75	LOW QUALITY PROTEIN: putative ATP-dependent RNA helicase TDRD12

0.66	GO:0043046	DNA methylation involved in gamete generation
0.65	GO:0034587	piRNA metabolic process
0.64	GO:1903955	positive regulation of protein targeting to mitochondrion
0.63	GO:0007140	male meiotic nuclear division
0.62	GO:0009566	fertilization
0.60	GO:0007283	spermatogenesis
0.60	GO:0031047	gene silencing by RNA
0.55	GO:0030154	cell differentiation
0.54	GO:0007275	multicellular organism development

0.63	GO:0004386	helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding

0.68	GO:1990923	PET complex
0.40	GO:0005829	cytosol

sp|Q587J8|KHD3L_HUMAN
KHDC3-like protein
Search

KHDC3L

0.97	KH domain containing 3 like, subcortical maternal complex member

0.59

GO:0003723

RNA binding

0.57

GO:0043234

protein complex

sp|Q58A44|PCOTH_HUMAN
Prostate collagen triple helix protein
Search

0.57	IgA FC receptor (Fragment)

sp|Q58A45|PAN3_HUMAN
PAB-dependent poly(A)-specific ribonuclease subunit PAN3
Search

PAN3

0.85	PAB-dependent poly(A)-specific ribonuclease subunit 3 (Fragment)

0.85	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.70	GO:0006397	mRNA processing
0.63	GO:0006468	protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.59	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0046872	metal ion binding

0.85	GO:0031251	PAN complex
0.30	GO:0016020	membrane

sp|Q58DX5|NADL2_HUMAN
Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2
Search

NAALADL2

0.96	N-acetylated alpha-linked acidic dipeptidase like 2

0.32

GO:0006508

proteolysis

0.35	GO:0005515	protein binding
0.32	GO:0004180	carboxypeptidase activity

0.55	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q58EX2|SDK2_HUMAN
Protein sidekick-2
Search

SDK2

0.87	Sidekick cell adhesion molecule 2

0.53	GO:0060219	camera-type eye photoreceptor cell differentiation
0.53	GO:0010842	retina layer formation
0.51	GO:0007416	synapse assembly
0.49	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:0045216	cell-cell junction organization

0.35	GO:0042802	identical protein binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.48	GO:0045202	synapse
0.37	GO:0030054	cell junction
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.33

GO:0004553

sp|Q58EX7|PKHG4_HUMAN
Puratrophin-1
Search

PLEKHG4

0.87	Pleckstrin homology and RhoGEF domain containing G4

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.35	GO:0006885	regulation of pH
0.35	GO:0035725	sodium ion transmembrane transport
0.33	GO:1902600	hydrogen ion transmembrane transport

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.35	GO:0015385	sodium:proton antiporter activity

0.30

GO:0016021

integral component of membrane

sp|Q58F21|BRDT_HUMAN
Bromodomain testis-specific protein
Search

BRDT

0.94	Bromodomain testis associated

0.86	GO:0001207	histone displacement
0.86	GO:0051039	positive regulation of transcription involved in meiotic cell cycle
0.85	GO:0007141	male meiosis I
0.81	GO:0043484	regulation of RNA splicing
0.79	GO:0007283	spermatogenesis
0.76	GO:0006338	chromatin remodeling
0.50	GO:0016569	covalent chromatin modification
0.49	GO:0030154	cell differentiation
0.48	GO:0008380	RNA splicing
0.47	GO:0006397	mRNA processing

0.84	GO:0070577	lysine-acetylated histone binding
0.42	GO:0003713	transcription coactivator activity
0.36	GO:0016301	kinase activity
0.35	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0003677	DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35

GO:0003980

sp|Q58FF3|ENPLL_HUMAN
Putative endoplasmin-like protein
Search

0.60	endoplasmin

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.57	GO:0031247	actin rod assembly
0.56	GO:0071318	cellular response to ATP
0.54	GO:1903513	endoplasmic reticulum to cytosol transport
0.54	GO:0032527	protein exit from endoplasmic reticulum
0.52	GO:0036293	response to decreased oxygen levels
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.50	GO:0043666	regulation of phosphoprotein phosphatase activity
0.50	GO:0043066	negative regulation of apoptotic process

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0050750	low-density lipoprotein particle receptor binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019903	protein phosphatase binding
0.42	GO:0003723	RNA binding
0.34	GO:0019104	DNA N-glycosylase activity
0.33	GO:0005509	calcium ion binding

0.54	GO:0005788	endoplasmic reticulum lumen
0.52	GO:0030496	midbody
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0034663	endoplasmic reticulum chaperone complex
0.47	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0005829	cytosol
0.43	GO:0042470	melanosome
0.39	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.34

EC:3.2.2

GO:0019104

sp|Q58FF6|H90B4_HUMAN
Putative heat shock protein HSP 90-beta 4
Search

0.10	Putative heat shock protein HSP 90-beta 4

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.59	GO:1901389	negative regulation of transforming growth factor beta activation
0.57	GO:1905323	telomerase holoenzyme complex assembly
0.56	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.56	GO:0071157	negative regulation of cell cycle arrest
0.55	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.55	GO:2000010	positive regulation of protein localization to cell surface
0.55	GO:0060330	regulation of response to interferon-gamma

0.71	GO:0051082	unfolded protein binding
0.56	GO:0043008	ATP-dependent protein binding
0.56	GO:1990226	histone methyltransferase binding
0.55	GO:0070182	DNA polymerase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097718	disordered domain specific binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0042826	histone deacetylase binding

0.55	GO:0034751	aryl hydrocarbon receptor complex
0.51	GO:0008180	COP9 signalosome
0.47	GO:0005829	cytosol
0.46	GO:0005576	extracellular region
0.43	GO:0042470	melanosome
0.43	GO:1990917	ooplasm
0.42	GO:1990913	sperm head plasma membrane
0.41	GO:0005739	mitochondrion
0.41	GO:0031526	brush border membrane
0.40	GO:0016234	inclusion body

0.33

GO:0016887

sp|Q58FF7|H90B3_HUMAN
Putative heat shock protein HSP 90-beta-3
Search

0.83	Heat shock protein 90 alpha family class B member 1

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0070062	extracellular exosome
0.38	GO:0005737	cytoplasm

sp|Q58FF8|H90B2_HUMAN
Putative heat shock protein HSP 90-beta 2
Search

0.86	Putative heat shock protein HSP 90-beta 2

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.48	GO:1901389	negative regulation of transforming growth factor beta activation
0.47	GO:1905323	telomerase holoenzyme complex assembly
0.46	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.46	GO:0071157	negative regulation of cell cycle arrest
0.46	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.46	GO:0051973	positive regulation of telomerase activity
0.46	GO:0007004	telomere maintenance via telomerase
0.46	GO:0032516	positive regulation of phosphoprotein phosphatase activity

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.46	GO:0070182	DNA polymerase binding
0.46	GO:0043008	ATP-dependent protein binding
0.46	GO:1990226	histone methyltransferase binding
0.46	GO:0097718	disordered domain specific binding
0.45	GO:0042826	histone deacetylase binding

0.46	GO:0034751	aryl hydrocarbon receptor complex
0.43	GO:0008180	COP9 signalosome
0.43	GO:0005576	extracellular region
0.41	GO:0005829	cytosol
0.39	GO:0031982	vesicle
0.38	GO:0005739	mitochondrion
0.35	GO:0032587	ruffle membrane
0.35	GO:0043209	myelin sheath

0.33

GO:0016887

sp|Q58FG0|HS905_HUMAN
Putative heat shock protein HSP 90-alpha A5
Search

0.69	Heat shock protein HSP 90-alpha (Fragment)

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.53	GO:0009266	response to temperature stimulus
0.52	GO:0046677	response to antibiotic
0.43	GO:1905323	telomerase holoenzyme complex assembly
0.42	GO:0051973	positive regulation of telomerase activity
0.42	GO:0007004	telomere maintenance via telomerase
0.42	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.41	GO:0045040	protein import into mitochondrial outer membrane
0.41	GO:0051131	chaperone-mediated protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0030235	nitric-oxide synthase regulator activity
0.43	GO:0030911	TPR domain binding
0.42	GO:0070182	DNA polymerase binding
0.42	GO:0097110	scaffold protein binding
0.42	GO:0097718	disordered domain specific binding
0.41	GO:1990782	protein tyrosine kinase binding

0.46	GO:0005634	nucleus
0.41	GO:0032587	ruffle membrane
0.41	GO:0005737	cytoplasm
0.41	GO:0043209	myelin sheath
0.36	GO:0043234	protein complex
0.36	GO:0097708	intracellular vesicle

0.38

GO:0016887

sp|Q58FG1|HS904_HUMAN
Putative heat shock protein HSP 90-alpha A4
Search

0.79	Heat shock protein 90 alpha family class A member 1

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.55	GO:0009266	response to temperature stimulus
0.54	GO:0046677	response to antibiotic
0.43	GO:1905323	telomerase holoenzyme complex assembly
0.43	GO:0043627	response to estrogen
0.42	GO:0051973	positive regulation of telomerase activity
0.42	GO:0007004	telomere maintenance via telomerase
0.42	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.42	GO:0045040	protein import into mitochondrial outer membrane

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0030235	nitric-oxide synthase regulator activity
0.43	GO:0030911	TPR domain binding
0.43	GO:0070182	DNA polymerase binding
0.42	GO:0097110	scaffold protein binding
0.42	GO:0097718	disordered domain specific binding
0.42	GO:1990782	protein tyrosine kinase binding

0.48	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.42	GO:0032587	ruffle membrane
0.41	GO:0043209	myelin sheath
0.36	GO:0043234	protein complex

0.37

GO:0016887

sp|Q58G82|SY14L_HUMAN
Putative synaptotagmin-14-like protein
Search

0.10	Synaptotagmin-14 isoform 2 (Fragment)

0.61	GO:0006887	exocytosis
0.51	GO:0017158	regulation of calcium ion-dependent exocytosis
0.50	GO:0097480	establishment of synaptic vesicle localization
0.50	GO:0099504	synaptic vesicle cycle
0.50	GO:0099003	vesicle-mediated transport in synapse
0.49	GO:0006906	vesicle fusion
0.49	GO:0099643	signal release from synapse
0.49	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.47	GO:0006836	neurotransmitter transport
0.46	GO:0001505	regulation of neurotransmitter levels

0.50	GO:0019905	syntaxin binding
0.49	GO:0005544	calcium-dependent phospholipid binding
0.49	GO:0030276	clathrin binding
0.45	GO:0005509	calcium ion binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity
0.35	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity

0.40	GO:0005886	plasma membrane
0.34	GO:0098793	presynapse
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.154	GO:0035005
0.35	KEGG:R05795	GO:0035005

sp|Q58HT5|AWAT1_HUMAN
Acyl-CoA wax alcohol acyltransferase 1
Search

0.88	LOW QUALITY PROTEIN: acyl-CoA wax alcohol acyltransferase 1

0.51	GO:0010025	wax biosynthetic process
0.38	GO:0006629	lipid metabolic process
0.37	GO:0001878	response to yeast
0.36	GO:0034308	primary alcohol metabolic process
0.36	GO:0034754	cellular hormone metabolic process
0.36	GO:0050892	intestinal absorption
0.36	GO:0006690	icosanoid metabolic process
0.34	GO:0032787	monocarboxylic acid metabolic process
0.33	GO:0006071	glycerol metabolic process
0.33	GO:0009966	regulation of signal transduction

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.37	GO:0003924	GTPase activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008475	procollagen-lysine 5-dioxygenase activity
0.33	GO:0031418	L-ascorbic acid binding
0.32	GO:0005506	iron ion binding
0.32	GO:0003777	microtubule motor activity

0.46	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.64

GO:0016747

sp|Q58WW2|DCAF6_HUMAN
DDB1- and CUL4-associated factor 6
Search

DCAF6

0.95	DDB1-and CUL4-associated factor 6 isoform b

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0016567	protein ubiquitination
0.43	GO:0043687	post-translational protein modification

0.83	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.38	GO:0005515	protein binding
0.35	GO:0003723	RNA binding

0.84	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.80	GO:0005925	focal adhesion
0.67	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part

sp|Q59EK9|RUN3A_HUMAN
RUN domain-containing protein 3A
Search

RUNDC3A

0.97	RUN domain-containing protein 3A

0.86	GO:0031284	positive regulation of guanylate cyclase activity
0.57	GO:0007264	small GTPase mediated signal transduction

0.86	GO:0030250	guanylate cyclase activator activity
0.86	GO:0051428	peptide hormone receptor binding
0.57	GO:0030695	GTPase regulator activity

0.69	GO:0005829	cytosol
0.56	GO:0005886	plasma membrane

sp|Q59GN2|R39L5_HUMAN
Putative 60S ribosomal protein L39-like 5
Search

RPL39

0.83	Angiomotin like 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.42	GO:0007283	spermatogenesis
0.38	GO:0002227	innate immune response in mucosa
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005615	extracellular space
0.34	GO:0005844	polysome

sp|Q59H18|TNI3K_HUMAN
Serine/threonine-protein kinase TNNI3K
Search

TNNI3K

0.85	Serine/threonine-protein kinase TNNI3K

0.62	GO:0006468	protein phosphorylation
0.48	GO:1903779	regulation of cardiac conduction
0.47	GO:0002027	regulation of heart rate
0.46	GO:0086069	bundle of His cell to Purkinje myocyte communication
0.45	GO:0055117	regulation of cardiac muscle contraction
0.41	GO:0018212	peptidyl-tyrosine modification
0.39	GO:0006508	proteolysis
0.39	GO:0035556	intracellular signal transduction

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0031013	troponin I binding
0.44	GO:0008022	protein C-terminus binding
0.42	GO:0070001	aspartic-type peptidase activity
0.40	GO:0004175	endopeptidase activity
0.39	GO:0004871	signal transducer activity
0.37	GO:0046872	metal ion binding

0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q5BIV9|SPRN_HUMAN
Shadow of prion protein
Search

SPRN

0.97	Shadoo protein Sho

0.50	GO:0006606	protein import into nucleus
0.37	GO:0006501	C-terminal protein lipidation
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0007165	signal transduction
0.32	GO:0006508	proteolysis

0.38	GO:0003676	nucleic acid binding
0.33	GO:0005198	structural molecule activity
0.33	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.32	GO:0008233	peptidase activity
0.32	GO:0046872	metal ion binding

0.78	GO:0031225	anchored component of membrane
0.47	GO:0005730	nucleolus
0.46	GO:0031982	vesicle
0.45	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.35	GO:0005576	extracellular region
0.33	GO:0005882	intermediate filament
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.4.17

GO:0004114

sp|Q5BJD5|TM41B_HUMAN
Transmembrane protein 41B
Search

TMEM41B

0.97	Transmembrane protein 41B

0.45	GO:0007399	nervous system development
0.43	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.43	GO:0000904	cell morphogenesis involved in differentiation
0.42	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0006935	chemotaxis
0.40	GO:0006928	movement of cell or subcellular component

0.32

GO:0003676

nucleic acid binding

0.30

GO:0044425

membrane part

sp|Q5BJE1|CC178_HUMAN
Coiled-coil domain-containing protein 178
Search

CCDC178

0.97	Coiled-coil domain-containing protein 178

sp|Q5BJF2|TMM97_HUMAN
Transmembrane protein 97
Search

TMEM97

0.97	Transmembrane protein 97

0.61	GO:0042632	cholesterol homeostasis
0.37	GO:0051642	centrosome localization
0.37	GO:0061512	protein localization to cilium
0.36	GO:0042073	intraciliary transport
0.36	GO:0060271	cilium assembly
0.30	GO:0001558	regulation of cell growth

0.30

GO:0005515

protein binding

0.74	GO:0005791	rough endoplasmic reticulum
0.72	GO:0031965	nuclear membrane
0.71	GO:0005764	lysosome
0.64	GO:0005789	endoplasmic reticulum membrane
0.63	GO:0098588	bounding membrane of organelle
0.52	GO:0005829	cytosol
0.52	GO:0005886	plasma membrane
0.36	GO:0030992	intraciliary transport particle B
0.36	GO:0005813	centrosome
0.36	GO:0005929	cilium

sp|Q5BJF6|ODFP2_HUMAN
Outer dense fiber protein 2
Search

ODF2

0.94	LOW QUALITY PROTEIN: outer dense fiber protein 2

0.85	GO:0010457	centriole-centriole cohesion
0.63	GO:0008104	protein localization
0.55	GO:0007283	spermatogenesis
0.51	GO:1902017	regulation of cilium assembly
0.51	GO:0030154	cell differentiation
0.50	GO:0007275	multicellular organism development
0.48	GO:0022412	cellular process involved in reproduction in multicellular organism
0.47	GO:0003006	developmental process involved in reproduction
0.44	GO:0097711	ciliary basal body-plasma membrane docking
0.42	GO:0000086	G2/M transition of mitotic cell cycle

0.49	GO:0017137	Rab GTPase binding
0.40	GO:0005200	structural constituent of cytoskeleton

0.85	GO:0120103	centriolar subdistal appendage
0.84	GO:0097539	ciliary transition fiber
0.82	GO:0005814	centriole
0.75	GO:0005813	centrosome
0.53	GO:0000922	spindle pole
0.53	GO:0001520	outer dense fiber
0.52	GO:0005874	microtubule
0.50	GO:0036064	ciliary basal body
0.40	GO:0005634	nucleus
0.39	GO:0005829	cytosol

sp|Q5BJH2|TM128_HUMAN
Transmembrane protein 128
Search

TMEM128

0.53	Transmembrane domain-containing protein (Fragment)

0.35	GO:0007212	dopamine receptor signaling pathway
0.35	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway

0.36	GO:0004952	dopamine neurotransmitter receptor activity
0.34	GO:0005515	protein binding

0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005622	intracellular

sp|Q5BJH7|YIF1B_HUMAN
Protein YIF1B
Search

YIF1B

0.97	Yip1 interacting factor homolog B

0.47

GO:0006888

ER to Golgi vesicle-mediated transport

0.50	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.49	GO:0030173	integral component of Golgi membrane
0.48	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.45	GO:0005789	endoplasmic reticulum membrane

sp|Q5BKT4|AG10A_HUMAN
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
Search

0.88	Asparagine-linked glycosylation 10

0.83	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.54	GO:0060117	auditory receptor cell development
0.51	GO:0007605	sensory perception of sound
0.39	GO:1901980	positive regulation of inward rectifier potassium channel activity
0.38	GO:0060050	positive regulation of protein glycosylation
0.38	GO:0006486	protein glycosylation
0.34	GO:0048366	leaf development
0.33	GO:0009651	response to salt stress
0.32	GO:0006468	protein phosphorylation

0.85	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
0.43	GO:0106073	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity
0.37	GO:0015459	potassium channel regulator activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

GO:0004583

sp|Q5BKU9|OXLD1_HUMAN
Oxidoreductase-like domain-containing protein 1
Search

OXLD1

0.96	Oxidoreductase like domain containing 1

0.49

GO:0007601

visual perception

0.53	GO:0030553	cGMP binding
0.49	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

0.56	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:3.1.4.17

GO:0004114

sp|Q5BKX5|CS054_HUMAN
UPF0692 protein C19orf54
Search

0.42	GO:0006744	ubiquinone biosynthetic process
0.38	GO:0016310	phosphorylation

0.38

GO:0016301

kinase activity

0.38	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q5BKX6|S45A4_HUMAN
Solute carrier family 45 member 4
Search

SLC45A4

0.97	Solute carrier family 45 member 4

0.57	GO:0015770	sucrose transport
0.47	GO:0055085	transmembrane transport

0.59

GO:0008506

sucrose:proton symporter activity

0.30

GO:0016020

membrane

sp|Q5BKX8|MURC_HUMAN
Muscle-related coiled-coil protein
Search

CAVIN4

0.97	Caveolae-associated protein 4

0.77	GO:0035023	regulation of Rho protein signal transduction
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0007517	muscle organ development
0.42	GO:0030154	cell differentiation
0.39	GO:0014706	striated muscle tissue development
0.38	GO:0007009	plasma membrane organization
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0007266	Rho protein signal transduction
0.36	GO:0031032	actomyosin structure organization
0.36	GO:0010927	cellular component assembly involved in morphogenesis

0.36	GO:0005515	protein binding
0.35	GO:0005096	GTPase activator activity
0.35	GO:0008307	structural constituent of muscle

0.62	GO:0005901	caveola
0.58	GO:0030018	Z disc
0.42	GO:0042383	sarcolemma
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q5BKY1|LRC10_HUMAN
Leucine-rich repeat-containing protein 10
Search

LRRC10

0.91	LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 10

0.79	GO:0055013	cardiac muscle cell development
0.56	GO:0001947	heart looping
0.56	GO:0060047	heart contraction
0.36	GO:0006468	protein phosphorylation
0.34	GO:0016485	protein processing
0.33	GO:0006952	defense response
0.33	GO:0009190	cyclic nucleotide biosynthetic process
0.33	GO:0006518	peptide metabolic process
0.33	GO:0007165	signal transduction
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0051393	alpha-actinin binding
0.67	GO:0003779	actin binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0004181	metallocarboxypeptidase activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0043168	anion binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0004185	serine-type carboxypeptidase activity

0.74	GO:0030017	sarcomere
0.63	GO:0005856	cytoskeleton
0.57	GO:0005634	nucleus
0.56	GO:0005739	mitochondrion
0.34	GO:0009986	cell surface
0.34	GO:0005615	extracellular space
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0004674

sp|Q5BKY6|YV018_HUMAN
Putative uncharacterized protein DKFZp434K191
Search

sp|Q5BKY9|F133B_HUMAN
Protein FAM133B
Search

0.44

GO:0006468

protein phosphorylation

0.47	GO:0003723	RNA binding
0.44	GO:0004672	protein kinase activity
0.43	GO:0005515	protein binding
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005509	calcium ion binding

0.30

GO:0031224

intrinsic component of membrane

sp|Q5BKZ1|ZN326_HUMAN
DBIRD complex subunit ZNF326
Search

ZNF326

0.84	DBIRD complex subunit ZNF326

0.55	GO:0043484	regulation of RNA splicing
0.52	GO:0032784	regulation of DNA-templated transcription, elongation
0.51	GO:0008380	RNA splicing
0.49	GO:0006397	mRNA processing
0.42	GO:0006351	transcription, DNA-templated
0.39	GO:0045893	positive regulation of transcription, DNA-templated

0.57	GO:0000993	RNA polymerase II core binding
0.55	GO:0003677	DNA binding
0.42	GO:0046872	metal ion binding
0.37	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.60	GO:0044609	DBIRD complex
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0044446	intracellular organelle part

sp|Q5BLP8|CD048_HUMAN
Neuropeptide-like protein C4orf48
Search

NAT8L

0.68	N-acetyltransferase 8 like

0.76	GO:0007218	neuropeptide signaling pathway
0.35	GO:0034968	histone lysine methylation

0.41	GO:0017188	aspartate N-acetyltransferase activity
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.41	GO:0005576	extracellular region
0.34	GO:0031966	mitochondrial membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:2.3.1.17	GO:0017188
0.41	KEGG:R00487	GO:0017188

sp|Q5BN46|CI116_HUMAN
UPF0691 protein C9orf116
Search

0.55

GO:0005515

protein binding

sp|Q5BVD1|TTMP_HUMAN
TPA-induced transmembrane protein
Search

0.93	TPA-induced transmembrane protein homolog

0.36

GO:0005515

protein binding

0.40	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q5C9Z4|NOM1_HUMAN
Nucleolar MIF4G domain-containing protein 1
Search

NOM1

0.93	LOW QUALITY PROTEIN: nucleolar MIF4G domain-containing protein 1

0.57	GO:0048820	hair follicle maturation
0.45	GO:0042254	ribosome biogenesis
0.44	GO:0022008	neurogenesis

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.51

GO:0005730

nucleolus

sp|Q5CZ79|AN20B_HUMAN
Ankyrin repeat domain-containing protein 20B
Search

0.95	Ankyrin repeat domain-containing protein 20B

0.51	GO:0045599	negative regulation of fat cell differentiation
0.47	GO:0040015	negative regulation of multicellular organism growth
0.47	GO:0060259	regulation of feeding behavior
0.47	GO:0046621	negative regulation of organ growth
0.47	GO:0046627	negative regulation of insulin receptor signaling pathway
0.46	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.45	GO:0019217	regulation of fatty acid metabolic process
0.45	GO:0042593	glucose homeostasis
0.38	GO:0065009	regulation of molecular function
0.36	GO:2001141	regulation of RNA biosynthetic process

0.42	GO:0005515	protein binding
0.42	GO:0008200	ion channel inhibitor activity
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.36	GO:0003677	DNA binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005813	centrosome
0.45	GO:0005884	actin filament
0.45	GO:0005886	plasma membrane
0.44	GO:0070062	extracellular exosome
0.40	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.3.1.225

GO:0019706

sp|Q5CZA5|ZN805_HUMAN
Zinc finger protein 805
Search

0.67	Zinc finger protein 805

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.37	GO:0006468	protein phosphorylation
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0043043	peptide biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.37	GO:0004672	protein kinase activity
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003735	structural constituent of ribosome

0.43	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0043228	non-membrane-bounded organelle

sp|Q5CZC0|FSIP2_HUMAN
Fibrous sheath-interacting protein 2
Search

FSIP2

0.88	Fibrous sheath interacting protein 2

0.35	GO:0046872	metal ion binding
0.32	GO:0005515	protein binding

0.60	GO:0005739	mitochondrion
0.32	GO:0031514	motile cilium

sp|Q5D0E6|DALD3_HUMAN
DALR anticodon-binding domain-containing protein 3
Search

DALRD3

0.97	DALR anticodon-binding domain-containing protein 3

0.77	GO:0006420	arginyl-tRNA aminoacylation
0.33	GO:0006177	GMP biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.77	GO:0004814	arginine-tRNA ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0003938	IMP dehydrogenase activity
0.33	GO:0031418	L-ascorbic acid binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0005506	iron ion binding

0.32	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:6.1.1.19

GO:0004814

sp|Q5D1E8|ZC12A_HUMAN
Endoribonuclease ZC3H12A
Search

ZC3H12A

0.94	Zinc finger CCCH-type containing 12A

0.68	GO:2000625	regulation of miRNA catabolic process
0.67	GO:0044828	negative regulation by host of viral genome replication
0.66	GO:1904636	response to ionomycin
0.66	GO:1990869	cellular response to chemokine
0.66	GO:1903003	positive regulation of protein deubiquitination
0.66	GO:2000630	positive regulation of miRNA metabolic process
0.66	GO:1903936	cellular response to sodium arsenite
0.66	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA
0.66	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.66	GO:0071362	cellular response to ether

0.64	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.64	GO:0035198	miRNA binding
0.64	GO:0035613	RNA stem-loop binding
0.59	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.58	GO:0003682	chromatin binding
0.56	GO:0004532	exoribonuclease activity
0.55	GO:0043022	ribosome binding
0.53	GO:0004521	endoribonuclease activity
0.51	GO:0046872	metal ion binding
0.45	GO:0003677	DNA binding

0.64	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.60	GO:0000932	P-body
0.59	GO:0005791	rough endoplasmic reticulum
0.53	GO:0005654	nucleoplasm
0.53	GO:0005856	cytoskeleton
0.47	GO:0043234	protein complex
0.38	GO:0098588	bounding membrane of organelle

sp|Q5D862|FILA2_HUMAN
Filaggrin-2
Search

FLG2

0.92

Hornerin

0.60	GO:0061436	establishment of skin barrier
0.41	GO:0043312	neutrophil degranulation
0.41	GO:0031424	keratinization
0.38	GO:0043163	cell envelope organization
0.36	GO:0002244	hematopoietic progenitor cell differentiation
0.35	GO:0018149	peptide cross-linking
0.34	GO:0012501	programmed cell death
0.32	GO:0006606	protein import into nucleus
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.68	GO:0005509	calcium ion binding
0.57	GO:0046914	transition metal ion binding
0.51	GO:0005198	structural molecule activity
0.33	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0008139	nuclear localization sequence binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0001533	cornified envelope
0.44	GO:0036457	keratohyalin granule
0.40	GO:0070062	extracellular exosome
0.40	GO:0030141	secretory granule
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0044433	cytoplasmic vesicle part
0.38	GO:0005766	primary lysosome
0.38	GO:0031983	vesicle lumen
0.38	GO:0005775	vacuolar lumen
0.37	GO:0005634	nucleus

sp|Q5DID0|UROL1_HUMAN
Uromodulin-like 1
Search

UMODL1

0.77	Uromodulin like 1

0.71	GO:0010466	negative regulation of peptidase activity
0.60	GO:2000354	regulation of ovarian follicle development
0.59	GO:0097211	cellular response to gonadotropin-releasing hormone
0.58	GO:0060612	adipose tissue development
0.55	GO:0007338	single fertilization
0.53	GO:0048609	multicellular organismal reproductive process
0.51	GO:0042981	regulation of apoptotic process
0.43	GO:0010468	regulation of gene expression

0.71	GO:0030414	peptidase inhibitor activity
0.69	GO:0005509	calcium ion binding
0.33	GO:0005201	extracellular matrix structural constituent

0.62	GO:0005576	extracellular region
0.55	GO:0009897	external side of plasma membrane
0.30	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q5DJT8|CT452_HUMAN
Cancer/testis antigen family 45 member A2
Search

sp|Q5DT21|ISK9_HUMAN
Serine protease inhibitor Kazal-type 9
Search

SPINK9

0.97	Serine protease inhibitor Kazal-type 9

0.72	GO:0010951	negative regulation of endopeptidase activity
0.62	GO:1902572	negative regulation of serine-type peptidase activity
0.62	GO:1900003	regulation of serine-type endopeptidase activity
0.61	GO:0060046	regulation of acrosome reaction
0.46	GO:0070268	cornification
0.41	GO:0006508	proteolysis
0.36	GO:0001558	regulation of cell growth
0.34	GO:0016310	phosphorylation

0.75	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0008233	peptidase activity
0.40	GO:0005515	protein binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0017171	serine hydrolase activity
0.34	GO:0016301	kinase activity

0.58	GO:0001669	acrosomal vesicle
0.52	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.41

GO:0008233

sp|Q5DX21|IGS11_HUMAN
Immunoglobulin superfamily member 11
Search

IGSF11

0.97	Immunoglobulin superfamily member 11

0.50	GO:0050934	late stripe melanocyte differentiation
0.48	GO:0097324	melanocyte migration
0.41	GO:0040008	regulation of growth
0.41	GO:0007155	cell adhesion
0.40	GO:0048565	digestive tract development
0.33	GO:0045663	positive regulation of myoblast differentiation
0.33	GO:0007224	smoothened signaling pathway
0.33	GO:0045664	regulation of neuron differentiation
0.32	GO:0048598	embryonic morphogenesis

0.33

GO:0005515

protein binding

0.41	GO:0005923	bicellular tight junction
0.40	GO:0005881	cytoplasmic microtubule
0.39	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane
0.36	GO:0005912	adherens junction
0.33	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

sp|Q5EB52|MEST_HUMAN
Mesoderm-specific transcript homolog protein
Search

MEST

0.97	Mesoderm specific transcript

0.37	GO:0010883	regulation of lipid storage
0.37	GO:0032526	response to retinoic acid
0.35	GO:0007498	mesoderm development
0.33	GO:0043547	positive regulation of GTPase activity
0.32	GO:0007049	cell cycle

0.35	GO:0016787	hydrolase activity
0.33	GO:0005096	GTPase activator activity

0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016787

sp|Q5EBL2|ZN628_HUMAN
Zinc finger protein 628
Search

ZNF628

0.96	LOW QUALITY PROTEIN: zinc finger protein 628

0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.35	GO:0006898	receptor-mediated endocytosis
0.31	GO:0006468	protein phosphorylation

0.51	GO:0003676	nucleic acid binding
0.50	GO:0003700	DNA binding transcription factor activity
0.39	GO:0046872	metal ion binding
0.36	GO:0005044	scavenger receptor activity
0.33	GO:0008080	N-acetyltransferase activity
0.31	GO:0004672	protein kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0008080

sp|Q5EBL4|RIPL1_HUMAN
RILP-like protein 1
Search

RILPL1

0.97	Rab interacting lysosomal protein like 1

0.61	GO:1903445	protein transport from ciliary membrane to plasma membrane
0.58	GO:0003382	epithelial cell morphogenesis
0.55	GO:1901214	regulation of neuron death
0.47	GO:0060271	cilium assembly
0.33	GO:0006915	apoptotic process
0.33	GO:0072583	clathrin-dependent endocytosis

0.68	GO:0046983	protein dimerization activity
0.49	GO:0051959	dynein light intermediate chain binding
0.45	GO:0031267	small GTPase binding
0.33	GO:0030276	clathrin binding
0.33	GO:0035091	phosphatidylinositol binding
0.33	GO:0003779	actin binding

0.54	GO:0005929	cilium
0.53	GO:0005813	centrosome
0.49	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.45	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0005886	plasma membrane
0.35	GO:0005814	centriole
0.33	GO:0005905	clathrin-coated pit
0.33	GO:0030136	clathrin-coated vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q5EBL8|PDZ11_HUMAN
PDZ domain-containing protein 11
Search

PDZD11

0.97	PDZ domain-containing protein 11

0.80	GO:1903361	protein localization to basolateral plasma membrane
0.77	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.71	GO:0099643	signal release from synapse
0.71	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.66	GO:0006836	neurotransmitter transport
0.63	GO:0001505	regulation of neurotransmitter levels
0.60	GO:0051649	establishment of localization in cell
0.60	GO:0060119	inner ear receptor cell development
0.57	GO:0090596	sensory organ morphogenesis
0.55	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound

0.64	GO:0008022	protein C-terminus binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0046982	protein heterodimerization activity
0.34	GO:0005096	GTPase activator activity

0.74	GO:0016323	basolateral plasma membrane
0.70	GO:0097458	neuron part
0.67	GO:0005911	cell-cell junction
0.66	GO:0044456	synapse part
0.56	GO:1990696	USH2 complex
0.54	GO:0005829	cytosol
0.52	GO:0098862	cluster of actin-based cell projections
0.50	GO:0005929	cilium
0.43	GO:0005634	nucleus
0.39	GO:0005576	extracellular region

sp|Q5EBM0|CMPK2_HUMAN
UMP-CMP kinase 2, mitochondrial
Search

CMPK2

0.97	Cytidine/uridine monophosphate kinase 2

0.65	GO:0071222	cellular response to lipopolysaccharide
0.61	GO:0009132	nucleoside diphosphate metabolic process
0.60	GO:0046939	nucleotide phosphorylation
0.58	GO:0009142	nucleoside triphosphate biosynthetic process
0.55	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process
0.51	GO:0046075	dTTP metabolic process

0.65	GO:0009041	uridylate kinase activity
0.64	GO:0004127	cytidylate kinase activity
0.64	GO:0004550	nucleoside diphosphate kinase activity
0.57	GO:0004798	thymidylate kinase activity
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.51

GO:0005739

mitochondrion

0.65

EC:2.7.4

GO:0009041

sp|Q5EBM4|ZN542_HUMAN
Putative zinc finger protein 542
Search

0.10	Putative zinc finger protein 542

0.52	GO:2001141	regulation of RNA biosynthetic process
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.40	GO:0051253	negative regulation of RNA metabolic process
0.40	GO:0010558	negative regulation of macromolecule biosynthetic process
0.40	GO:0031327	negative regulation of cellular biosynthetic process
0.39	GO:0035118	embryonic pectoral fin morphogenesis
0.39	GO:0007576	nucleolar fragmentation
0.39	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.38	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.40	GO:0003682	chromatin binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding
0.32	GO:0008168	methyltransferase activity

0.43	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.32

GO:0008168

sp|Q5EBN2|TRI61_HUMAN
Putative tripartite motif-containing protein 61
Search

TRIM61

0.97	Tripartite motif containing 61

0.37	GO:0046596	regulation of viral entry into host cell
0.36	GO:1903901	negative regulation of viral life cycle
0.36	GO:0045087	innate immune response
0.35	GO:0048518	positive regulation of biological process
0.35	GO:0051090	regulation of DNA binding transcription factor activity
0.35	GO:0032897	negative regulation of viral transcription
0.35	GO:1902186	regulation of viral release from host cell
0.35	GO:0048251	elastic fiber assembly
0.35	GO:0044093	positive regulation of molecular function
0.34	GO:0016567	protein ubiquitination

0.60	GO:0008270	zinc ion binding
0.35	GO:0016874	ligase activity
0.34	GO:0004937	alpha1-adrenergic receptor activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0031624	ubiquitin conjugating enzyme binding
0.34	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0002039	p53 binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0019767	IgE receptor activity
0.33	GO:0019864	IgG binding

0.44	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0005615	extracellular space
0.33	GO:0032997	Fc receptor complex
0.33	GO:0043233	organelle lumen
0.33	GO:0030315	T-tubule
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0009897	external side of plasma membrane
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0120114	Sm-like protein family complex

0.35	EC:6	GO:0016874
0.34	KEGG:R03876	GO:0004842

sp|Q5EE01|CENPW_HUMAN
Centromere protein W
Search

CENPW

0.97	Centromere protein W

0.84	GO:0051382	kinetochore assembly
0.75	GO:0000278	mitotic cell cycle
0.59	GO:0007059	chromosome segregation
0.40	GO:0051301	cell division
0.39	GO:0034080	CENP-A containing nucleosome assembly
0.33	GO:0032259	methylation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.33	GO:0008168	methyltransferase activity

0.64	GO:0000776	kinetochore
0.58	GO:0005654	nucleoplasm
0.43	GO:0000779	condensed chromosome, centromeric region
0.43	GO:0016363	nuclear matrix
0.40	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

sp|Q5EG05|CAR16_HUMAN
Caspase recruitment domain-containing protein 16
Search

0.55	Caspase recruitment domain-containing protein 16

0.74	GO:0042981	regulation of apoptotic process
0.58	GO:0050706	regulation of interleukin-1 beta secretion
0.56	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
0.55	GO:0006508	proteolysis
0.55	GO:0071222	cellular response to lipopolysaccharide
0.54	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.53	GO:2000116	regulation of cysteine-type endopeptidase activity
0.53	GO:0032101	regulation of response to external stimulus
0.52	GO:0050716	positive regulation of interleukin-1 secretion
0.52	GO:0032731	positive regulation of interleukin-1 beta production

0.67	GO:0004197	cysteine-type endopeptidase activity
0.57	GO:0050700	CARD domain binding
0.51	GO:0019900	kinase binding
0.51	GO:0042802	identical protein binding
0.48	GO:0089720	caspase binding
0.44	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.37	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.36	GO:0097110	scaffold protein binding

0.58	GO:0097179	protease inhibitor complex
0.58	GO:0097169	AIM2 inflammasome complex
0.58	GO:0072559	NLRP3 inflammasome complex
0.57	GO:0072558	NLRP1 inflammasome complex
0.56	GO:0072557	IPAF inflammasome complex
0.42	GO:0005576	extracellular region
0.40	GO:0005739	mitochondrion
0.35	GO:0043005	neuron projection
0.33	GO:0005634	nucleus

0.67

EC:3.4.22

GO:0004197

sp|Q5F1R6|DJC21_HUMAN
DnaJ homolog subfamily C member 21
Search

DNAJC21

0.94	DnaJ heat shock protein family (Hsp40) member C21

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

sp|Q5FBB7|SGO1_HUMAN
Shugoshin 1
Search

SGO1

0.97	Shugoshin 1

0.87	GO:0071962	mitotic sister chromatid cohesion, centromeric
0.81	GO:0045132	meiotic chromosome segregation
0.70	GO:0010457	centriole-centriole cohesion
0.66	GO:0008608	attachment of spindle microtubules to kinetochore
0.38	GO:0051301	cell division
0.33	GO:0008016	regulation of heart contraction
0.32	GO:0007135	meiosis II
0.32	GO:0070192	chromosome organization involved in meiotic cell cycle

0.62

GO:0019900

kinase binding

0.77	GO:0000775	chromosome, centromeric region
0.63	GO:0000922	spindle pole
0.62	GO:0005813	centrosome
0.61	GO:0000793	condensed chromosome
0.61	GO:0005634	nucleus
0.56	GO:0005829	cytosol
0.56	GO:0031974	membrane-enclosed lumen
0.50	GO:0043234	protein complex
0.32	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

sp|Q5FVE4|ACBG2_HUMAN
Long-chain-fatty-acid--CoA ligase ACSBG2
Search

ACSBG2

0.95	Acyl-CoA synthetase bubblegum family member 2

0.61	GO:0001676	long-chain fatty acid metabolic process
0.45	GO:0051384	response to glucocorticoid
0.44	GO:0000038	very long-chain fatty acid metabolic process

0.62	GO:0004467	long-chain fatty acid-CoA ligase activity
0.59	GO:0047617	acyl-CoA hydrolase activity
0.45	GO:0031957	very long-chain fatty acid-CoA ligase activity

0.52	GO:0005829	cytosol
0.48	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.62

EC:6.2.1.3

GO:0004467

sp|Q5FWE3|PRRT3_HUMAN
Proline-rich transmembrane protein 3
Search

PRRT3

0.97	Proline-rich transmembrane protein 3

0.34	GO:0042138	meiotic DNA double-strand break formation
0.33	GO:0006310	DNA recombination

0.30

GO:0044425

membrane part

sp|Q5FWF4|ZRAB3_HUMAN
DNA annealing helicase and endonuclease ZRANB3
Search

ZRANB3

0.92	Zinc finger Ran-binding domain-containing protein 3

0.68	GO:0036292	DNA rewinding
0.66	GO:0000733	DNA strand renaturation
0.65	GO:0048478	replication fork protection
0.64	GO:0031297	replication fork processing
0.62	GO:0009411	response to UV
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.62	GO:0045910	negative regulation of DNA recombination
0.52	GO:0006281	DNA repair

0.67	GO:0036310	annealing helicase activity
0.66	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.64	GO:0004519	endonuclease activity
0.55	GO:0004536	deoxyribonuclease activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.33	GO:0003678	DNA helicase activity

0.63	GO:0043596	nuclear replication fork
0.30	GO:0031224	intrinsic component of membrane

sp|Q5FWF5|ESCO1_HUMAN
N-acetyltransferase ESCO1
Search

ESCO1

0.97	Establishment of sister chromatid cohesion N-acetyltransferase 1

0.86	GO:0034421	post-translational protein acetylation
0.77	GO:0007062	sister chromatid cohesion
0.76	GO:0006275	regulation of DNA replication
0.55	GO:0018394	peptidyl-lysine acetylation
0.39	GO:0071168	protein localization to chromatin
0.39	GO:0002244	hematopoietic progenitor cell differentiation
0.37	GO:0006302	double-strand break repair
0.36	GO:1990523	bone regeneration
0.35	GO:0031101	fin regeneration
0.35	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.56	GO:0061733	peptide-lysine-N-acetyltransferase activity
0.48	GO:0008270	zinc ion binding
0.40	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
0.38	GO:0042802	identical protein binding
0.32	GO:0016787	hydrolase activity

0.72	GO:0000785	chromatin
0.39	GO:0001741	XY body
0.39	GO:0010369	chromocenter
0.38	GO:0035861	site of double-strand break
0.38	GO:0031981	nuclear lumen
0.38	GO:0000775	chromosome, centromeric region
0.36	GO:0030054	cell junction
0.36	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.40

EC:2.3.1.32

GO:0004468

sp|Q5FWF6|ZN789_HUMAN
Zinc finger protein 789
Search

ZNF789

0.83	Zinc finger protein 30

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.41	GO:1902459	positive regulation of stem cell population maintenance
0.40	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.46	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding

0.47	GO:0005634	nucleus
0.44	GO:0005813	centrosome
0.42	GO:0031974	membrane-enclosed lumen
0.41	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome

sp|Q5FWF7|FBX48_HUMAN
F-box only protein 48
Search

FBXO48

0.97	LOW QUALITY PROTEIN: F-box only protein 48

sp|Q5FYA8|ARSH_HUMAN
Arylsulfatase H
Search

ARSH

0.46	Arylsulfatase H

0.39	GO:0006687	glycosphingolipid metabolic process
0.39	GO:0043687	post-translational protein modification
0.34	GO:0001501	skeletal system development

0.74	GO:0008484	sulfuric ester hydrolase activity
0.35	GO:0046872	metal ion binding

0.43	GO:0005794	Golgi apparatus
0.39	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0070062	extracellular exosome
0.34	GO:0031984	organelle subcompartment
0.34	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:3.1.6

GO:0008484

sp|Q5FYB0|ARSJ_HUMAN
Arylsulfatase J
Search

ARSJ

0.97	Arylsulfatase J

0.35	GO:0006687	glycosphingolipid metabolic process
0.35	GO:0043687	post-translational protein modification

0.74	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0046872	metal ion binding

0.36	GO:0005576	extracellular region
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:3.1.6

GO:0008484

sp|Q5FYB1|ARSI_HUMAN
Arylsulfatase I
Search

ARSI

0.97	Arylsulfatase I

0.36	GO:0006687	glycosphingolipid metabolic process
0.36	GO:0043687	post-translational protein modification

0.74	GO:0008484	sulfuric ester hydrolase activity
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0005576	extracellular region
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:3.1.6

GO:0008484

sp|Q5GAN3|RNS13_HUMAN
Probable inactive ribonuclease-like protein 13
Search

RNASE13

0.97	Ribonuclease A family member 13 (inactive)

0.51	GO:0003676	nucleic acid binding
0.49	GO:0004540	ribonuclease activity
0.48	GO:0004519	endonuclease activity

0.43

GO:0005576

extracellular region

sp|Q5GAN4|RNS12_HUMAN
Probable inactive ribonuclease-like protein 12
Search

RAI1

0.96	Probable inactive ribonuclease-like protein 12

0.48

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.51	GO:0003676	nucleic acid binding
0.51	GO:0004540	ribonuclease activity
0.49	GO:0004519	endonuclease activity

0.49	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q5GAN6|RNS10_HUMAN
Inactive ribonuclease-like protein 10
Search

sp|Q5GFL6|VWA2_HUMAN
von Willebrand factor A domain-containing protein 2
Search

VWA2

0.97	von Willebrand factor A domain-containing protein 2

0.65	GO:0007161	calcium-independent cell-matrix adhesion
0.61	GO:0046626	regulation of insulin receptor signaling pathway
0.56	GO:0051260	protein homooligomerization
0.47	GO:0010669	epithelial structure maintenance

0.68	GO:0005509	calcium ion binding
0.54	GO:0042802	identical protein binding

0.81	GO:0005604	basement membrane
0.72	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q5GH70|XKR9_HUMAN
XK-related protein 9
Search

XKR9

0.97	XK-related protein 9

0.30

GO:0044425

membrane part

sp|Q5GH72|XKR7_HUMAN
XK-related protein 7
Search

0.95	XK-related protein 7

0.30

GO:0044425

membrane part

sp|Q5GH73|XKR6_HUMAN
XK-related protein 6
Search

XKR6

0.94	XK-related protein 6

0.30

GO:0044425

membrane part

sp|Q5GH76|XKR4_HUMAN
XK-related protein 4
Search

XKR4

0.97	XK-related protein 4

0.30

GO:0044425

membrane part

sp|Q5GH77|XKR3_HUMAN
XK-related protein 3
Search

0.97	Membrane transport protein XK

0.50	GO:0031133	regulation of axon diameter
0.50	GO:0010961	cellular magnesium ion homeostasis
0.48	GO:0048741	skeletal muscle fiber development
0.48	GO:0042552	myelination
0.47	GO:0008361	regulation of cell size
0.46	GO:0006874	cellular calcium ion homeostasis
0.35	GO:0006865	amino acid transport
0.33	GO:0007338	single fertilization

0.35	GO:0005515	protein binding
0.32	GO:0005215	transporter activity

0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q5GJ75|TP8L3_HUMAN
Tumor necrosis factor alpha-induced protein 8-like protein 3
Search

TNFAIP8L3

0.97	LOW QUALITY PROTEIN: tumor necrosis factor alpha-induced protein 8-like protein 3

0.73	GO:0042981	regulation of apoptotic process
0.42	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.41	GO:0051897	positive regulation of protein kinase B signaling
0.41	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.41	GO:0006869	lipid transport
0.40	GO:0048017	inositol lipid-mediated signaling
0.39	GO:0015748	organophosphate ester transport
0.38	GO:0015711	organic anion transport
0.36	GO:0032007	negative regulation of TOR signaling
0.35	GO:0006644	phospholipid metabolic process

0.42	GO:0008526	phosphatidylinositol transporter activity
0.40	GO:0035091	phosphatidylinositol binding

0.39	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q5GLZ8|HERC4_HUMAN
Probable E3 ubiquitin-protein ligase HERC4
Search

HERC4

0.94	HECT and RLD domain containing E3 ubiquitin protein ligase 4

0.73	GO:0016567	protein ubiquitination
0.60	GO:0007283	spermatogenesis

0.73	GO:0004842	ubiquitin-protein transferase activity
0.49	GO:0061659	ubiquitin-like protein ligase activity
0.43	GO:0016874	ligase activity

0.63	GO:0001650	fibrillar center
0.54	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.43	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q5H8A3|NMS_HUMAN
Neuromedin-S
Search

NMS

0.97	Neuromedin-S

0.71	GO:0006940	regulation of smooth muscle contraction
0.69	GO:0007218	neuropeptide signaling pathway
0.67	GO:0045475	locomotor rhythm
0.58	GO:2000821	regulation of grooming behavior
0.56	GO:0097009	energy homeostasis
0.55	GO:0060259	regulation of feeding behavior
0.55	GO:0001659	temperature homeostasis
0.45	GO:0044497	positive regulation of blood pressure in other organism
0.45	GO:0120060	regulation of gastric emptying
0.45	GO:1902722	positive regulation of prolactin secretion

0.69	GO:0001664	G-protein coupled receptor binding
0.35	GO:0005179	hormone activity

0.50	GO:0005576	extracellular region
0.42	GO:0043195	terminal bouton
0.30	GO:0016020	membrane

sp|Q5H8A4|PIGG_HUMAN
GPI ethanolamine phosphate transferase 2
Search

PIGG

0.90	Phosphatidylinositol glycan anchor biosynthesis class G

0.76

GO:0006506

GPI anchor biosynthetic process

0.82

GO:0051377

mannose-ethanolamine phosphotransferase activity

0.51	GO:0005783	endoplasmic reticulum
0.46	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|Q5H8C1|FREM1_HUMAN
FRAS1-related extracellular matrix protein 1
Search

FREM1

0.89	FRAS1-related extracellular matrix protein 1

0.81	GO:0007160	cell-matrix adhesion
0.69	GO:0097094	craniofacial suture morphogenesis
0.58	GO:0007154	cell communication
0.36	GO:0033334	fin morphogenesis
0.31	GO:0015074	DNA integration

0.38	GO:0030246	carbohydrate binding
0.35	GO:0046872	metal ion binding
0.31	GO:0003676	nucleic acid binding

0.81	GO:0005604	basement membrane
0.30	GO:0044425	membrane part

sp|Q5H913|AR13A_HUMAN
ADP-ribosylation factor-like protein 13A
Search

ARL13A

0.96	ADP ribosylation factor like GTPase 13A

0.43	GO:0021943	formation of radial glial scaffolds
0.43	GO:0021830	interneuron migration from the subpallium to the cortex
0.43	GO:0070986	left/right axis specification
0.42	GO:0021532	neural tube patterning
0.42	GO:0001947	heart looping
0.42	GO:1905515	non-motile cilium assembly
0.41	GO:0007224	smoothened signaling pathway
0.41	GO:0009953	dorsal/ventral pattern formation
0.35	GO:0010226	response to lithium ion
0.34	GO:0009558	embryo sac cellularization

0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.45	GO:0005622	intracellular
0.42	GO:0005929	cilium
0.41	GO:0031253	cell projection membrane
0.39	GO:0098588	bounding membrane of organelle
0.36	GO:0043228	non-membrane-bounded organelle
0.33	GO:0043233	organelle lumen
0.32	GO:1990904	ribonucleoprotein complex

0.33

GO:0008168

sp|Q5H943|KKLC1_HUMAN
Kita-kyushu lung cancer antigen 1
Search

CT83

0.97	Cancer/testis antigen 83

0.30

GO:0044425

membrane part

sp|Q5H9B9|BM2KL_HUMAN
Putative BMP-2-inducible kinase-like protein
Search

0.96	BMP-2-inducible protein kinase

0.57	GO:0016310	phosphorylation
0.49	GO:0036211	protein modification process
0.47	GO:0044267	cellular protein metabolic process
0.45	GO:2000369	regulation of clathrin-dependent endocytosis
0.44	GO:0045747	positive regulation of Notch signaling pathway
0.44	GO:0030500	regulation of bone mineralization
0.39	GO:0050790	regulation of catalytic activity

0.60	GO:0016301	kinase activity
0.51	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.48	GO:0140096	catalytic activity, acting on a protein
0.46	GO:0032559	adenyl ribonucleotide binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0035612	AP-2 adaptor complex binding
0.42	GO:0019208	phosphatase regulator activity

0.43	GO:0016607	nuclear speck
0.35	GO:0005737	cytoplasm

0.51

GO:0016773

sp|Q5H9E4|S2553_HUMAN
Solute carrier family 25 member 53
Search

SLC25A53

0.96	Mitochondrial carrier triple repeat protein 6

0.51	GO:0006839	mitochondrial transport
0.41	GO:0055085	transmembrane transport
0.37	GO:0007015	actin filament organization

0.42	GO:0022857	transmembrane transporter activity
0.39	GO:0003785	actin monomer binding

0.44	GO:0005743	mitochondrial inner membrane
0.30	GO:0044425	membrane part

sp|Q5H9F3|BCORL_HUMAN
BCL-6 corepressor-like protein 1
Search

BCORL1

0.87	BCL6 corepressor like 1

0.48	GO:0016569	covalent chromatin modification
0.44	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.43	GO:0009887	animal organ morphogenesis
0.42	GO:0021915	neural tube development
0.42	GO:0060041	retina development in camera-type eye
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:0010468	regulation of gene expression
0.40	GO:0000415	negative regulation of histone H3-K36 methylation

0.38	GO:0042826	histone deacetylase binding
0.38	GO:0003714	transcription corepressor activity
0.37	GO:0031072	heat shock protein binding
0.37	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0008134	transcription factor binding

0.68	GO:0005654	nucleoplasm
0.55	GO:0005886	plasma membrane
0.38	GO:0031519	PcG protein complex
0.36	GO:0032040	small-subunit processome

0.37

GO:0004842

sp|Q5H9I0|TFDP3_HUMAN
Transcription factor Dp family member 3
Search

TFDP1

0.90	LOW QUALITY PROTEIN: transcription factor Dp-1

0.66	GO:0007049	cell cycle
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0070345	negative regulation of fat cell proliferation
0.53	GO:0043276	anoikis
0.49	GO:0008544	epidermis development
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:0051052	regulation of DNA metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.45	GO:0008134	transcription factor binding
0.43	GO:0019904	protein domain specific binding
0.43	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0003712	transcription cofactor activity
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0015299	solute:proton antiporter activity

0.74	GO:0005667	transcription factor complex
0.60	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.40	GO:0005829	cytosol
0.39	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q5H9J7|BEX5_HUMAN
Protein BEX5
Search

0.97	Brain expressed X-linked 5

0.54	GO:0051091	positive regulation of DNA binding transcription factor activity
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.47	GO:0042981	regulation of apoptotic process
0.46	GO:0051726	regulation of cell cycle

0.66	GO:0042802	identical protein binding
0.56	GO:0001102	RNA polymerase II activating transcription factor binding
0.50	GO:0005123	death receptor binding

0.61	GO:0005829	cytosol
0.51	GO:0005667	transcription factor complex

sp|Q5H9J9|T11X2_HUMAN
T-complex protein 11 X-linked protein 2
Search

TCP11

0.92	Nuclear RNA export factor 2

0.53	GO:1902490	regulation of sperm capacitation
0.50	GO:0010737	protein kinase A signaling
0.50	GO:0043949	regulation of cAMP-mediated signaling
0.47	GO:0007283	spermatogenesis
0.44	GO:0030154	cell differentiation
0.44	GO:0007275	multicellular organism development
0.36	GO:0019068	virion assembly
0.34	GO:0006351	transcription, DNA-templated

0.39	GO:0005515	protein binding
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0032549	ribonucleoside binding
0.33	GO:0003677	DNA binding

0.79	GO:0036126	sperm flagellum
0.79	GO:0001669	acrosomal vesicle
0.46	GO:0044441	ciliary part
0.38	GO:0005874	microtubule
0.30	GO:0016020	membrane

0.35

EC:2.7.7.6

GO:0003899

sp|Q5H9K5|ZMAT1_HUMAN
Zinc finger matrin-type protein 1
Search

ZMAT1

0.80	Zinc finger matrin-type protein 1

0.63	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.37	GO:0032501	multicellular organismal process
0.37	GO:0009888	tissue development
0.36	GO:0007164	establishment of tissue polarity
0.36	GO:0016567	protein ubiquitination
0.36	GO:0048523	negative regulation of cellular process
0.36	GO:0030154	cell differentiation
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0022414	reproductive process

0.63	GO:0002039	p53 binding
0.54	GO:0008270	zinc ion binding
0.49	GO:0003676	nucleic acid binding
0.35	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0031870	thromboxane A2 receptor binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.34	GO:0005096	GTPase activator activity
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0016874	ligase activity

0.40	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0044422	organelle part
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0097362	MCM8-MCM9 complex
0.35	GO:0005929	cilium
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0031594	neuromuscular junction
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0005911	cell-cell junction

0.34

GO:0016874

sp|Q5H9L2|TCAL5_HUMAN
Transcription elongation factor A protein-like 5
Search

0.97	Transcription elongation factor A like 5

0.62	GO:0006414	translational elongation
0.55	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0006351	transcription, DNA-templated
0.33	GO:0045892	negative regulation of transcription, DNA-templated

0.66	GO:0050699	WW domain binding
0.62	GO:0003746	translation elongation factor activity
0.35	GO:0010385	double-stranded methylated DNA binding
0.34	GO:0008270	zinc ion binding

0.50	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q5H9L4|TAF7L_HUMAN
Transcription initiation factor TFIID subunit 7-like
Search

TAF7L

0.87	TATA-box binding protein associated factor 7 like

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.57	GO:0006413	translational initiation
0.51	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.46	GO:0035067	negative regulation of histone acetylation
0.44	GO:0006469	negative regulation of protein kinase activity
0.42	GO:0030520	intracellular estrogen receptor signaling pathway
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0007283	spermatogenesis

0.58	GO:0003743	translation initiation factor activity
0.58	GO:0035035	histone acetyltransferase binding
0.53	GO:0003713	transcription coactivator activity
0.52	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0008134	transcription factor binding
0.48	GO:0061628	H3K27me3 modified histone binding
0.44	GO:0051427	hormone receptor binding
0.42	GO:0046982	protein heterodimerization activity
0.39	GO:0003700	DNA binding transcription factor activity

0.80	GO:0005669	transcription factor TFIID complex
0.46	GO:0033276	transcription factor TFTC complex
0.46	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.45	GO:0071339	MLL1 complex
0.41	GO:0005794	Golgi apparatus
0.35	GO:0010369	chromocenter
0.30	GO:0016020	membrane

sp|Q5H9M0|MUML1_HUMAN
PWWP domain-containing protein MUM1L1
Search

MUM1

0.95	Mutated melanoma-associated antigen 1

0.69	GO:0006325	chromatin organization
0.62	GO:0006281	DNA repair
0.36	GO:0055114	oxidation-reduction process
0.33	GO:0006468	protein phosphorylation

0.79	GO:0031491	nucleosome binding
0.40	GO:0048038	quinone binding
0.39	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.39	GO:0051539	4 iron, 4 sulfur cluster binding
0.36	GO:0046872	metal ion binding
0.36	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding

0.59	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.44	GO:0070062	extracellular exosome

0.39

EC:1.6.5.3

GO:0008137

sp|Q5H9R4|ARMX4_HUMAN
Armadillo repeat-containing X-linked protein 4
Search

0.86	Armadillo repeat-containing X-linked protein 4

0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0070727	cellular macromolecule localization
0.46	GO:0008104	protein localization

0.34

GO:0005515

protein binding

0.54	GO:0031307	integral component of mitochondrial outer membrane
0.37	GO:0005634	nucleus

sp|Q5H9R7|PP6R3_HUMAN
Serine/threonine-protein phosphatase 6 regulatory subunit 3
Search

PPP6R3

0.94	Sporulation-induced transcript 4-associated protein SAPLa

0.76	GO:0043666	regulation of phosphoprotein phosphatase activity
0.42	GO:0010469	regulation of receptor activity
0.40	GO:0048208	COPII vesicle coating

0.80	GO:0019903	protein phosphatase binding
0.43	GO:0005179	hormone activity

0.68	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.40	GO:0005576	extracellular region
0.38	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q5H9S7|DCA17_HUMAN
DDB1- and CUL4-associated factor 17
Search

DCAF17

0.97	DDB1- and CUL4-associated factor 17

0.72	GO:0016567	protein ubiquitination
0.36	GO:0043687	post-translational protein modification

0.34

GO:0005515

protein binding

0.60	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.38	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q5H9T9|FSCB_HUMAN
Fibrous sheath CABYR-binding protein
Search

FSCB

0.93	LOW QUALITY PROTEIN: fibrous sheath CABYR-binding protein

0.73	GO:0033234	negative regulation of protein sumoylation
0.40	GO:0006402	mRNA catabolic process
0.39	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0006364	rRNA processing
0.38	GO:0008033	tRNA processing
0.37	GO:0015889	cobalamin transport
0.37	GO:0051301	cell division
0.37	GO:0007049	cell cycle
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0009236	cobalamin biosynthetic process

0.43	GO:0005509	calcium ion binding
0.43	GO:0005515	protein binding
0.42	GO:0060090	molecular adaptor activity
0.41	GO:0008995	ribonuclease E activity
0.39	GO:0004521	endoribonuclease activity
0.38	GO:0008939	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
0.38	GO:0015420	cobalamin-transporting ATPase activity
0.37	GO:0000287	magnesium ion binding
0.37	GO:0003723	RNA binding
0.37	GO:0008270	zinc ion binding

0.66	GO:0031514	motile cilium
0.45	GO:0097223	sperm part
0.43	GO:0044441	ciliary part
0.40	GO:0009898	cytoplasmic side of plasma membrane
0.38	GO:0044462	external encapsulating structure part
0.38	GO:0019867	outer membrane
0.38	GO:0030313	cell envelope
0.37	GO:0005737	cytoplasm
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle

0.38	EC:2.4.2.21	GO:0008939
0.38	KEGG:R04148	GO:0008939

sp|Q5H9U9|DDX6L_HUMAN
Probable ATP-dependent RNA helicase DDX60-like
Search

DDX60

0.96	DEAD-box helicase 60 like

0.67	GO:1900245	positive regulation of MDA-5 signaling pathway
0.66	GO:1900246	positive regulation of RIG-I signaling pathway
0.58	GO:0009615	response to virus
0.57	GO:0002252	immune effector process
0.56	GO:0098542	defense response to other organism

0.59	GO:0003727	single-stranded RNA binding
0.57	GO:0003725	double-stranded RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0003690	double-stranded DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004386	helicase activity

0.58	GO:0045111	intermediate filament cytoskeleton
0.52	GO:0005829	cytosol
0.32	GO:0005634	nucleus

sp|Q5HY64|FA47C_HUMAN
Putative protein FAM47C
Search

0.51	GO:0031505	fungal-type cell wall organization
0.51	GO:0098507	polynucleotide 5' dephosphorylation

0.52	GO:0005199	structural constituent of cell wall
0.51	GO:0004651	polynucleotide 5'-phosphatase activity
0.39	GO:0003676	nucleic acid binding

0.51	GO:0009277	fungal-type cell wall
0.41	GO:0005634	nucleus

0.51

EC:3.1.3.33

GO:0004651

sp|Q5HY92|FIGN_HUMAN
Fidgetin
Search

FIGN

0.96	Fidgetin, microtubule severing factor

0.49	GO:0010569	regulation of double-strand break repair via homologous recombination
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008022	protein C-terminus binding
0.40	GO:0016887	ATPase activity

0.54	GO:0016363	nuclear matrix
0.37	GO:0005815	microtubule organizing center
0.37	GO:0005874	microtubule
0.33	GO:0005737	cytoplasm

0.40

GO:0016887

sp|Q5HY98|ZN766_HUMAN
Zinc finger protein 766
Search

0.71	Zinc finger protein 83

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044422	organelle part
0.33	GO:0043228	non-membrane-bounded organelle

sp|Q5HYA8|MKS3_HUMAN
Meckelin
Search

TMEM67

0.95	Transmembrane protein 67

0.85	GO:0010826	negative regulation of centrosome duplication
0.80	GO:0060271	cilium assembly
0.57	GO:0030433	ubiquitin-dependent ERAD pathway
0.45	GO:0060028	convergent extension involved in axis elongation
0.44	GO:0060027	convergent extension involved in gastrulation
0.43	GO:0003341	cilium movement
0.37	GO:0048754	branching morphogenesis of an epithelial tube
0.37	GO:0007368	determination of left/right symmetry
0.37	GO:0007507	heart development
0.36	GO:1902857	positive regulation of non-motile cilium assembly

0.61	GO:0031005	filamin binding
0.51	GO:0051082	unfolded protein binding
0.36	GO:0051787	misfolded protein binding
0.32	GO:0004721	phosphoprotein phosphatase activity
0.31	GO:0046872	metal ion binding

0.85	GO:0036038	MKS complex
0.59	GO:0060170	ciliary membrane
0.55	GO:0005813	centrosome
0.54	GO:0030659	cytoplasmic vesicle membrane
0.52	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005930	axoneme
0.30	GO:0016021	integral component of membrane

0.32

GO:0004721

sp|Q5HYC2|K2026_HUMAN
Uncharacterized protein KIAA2026
Search

sp|Q5HYI7|MTX3_HUMAN
Metaxin-3
Search

MTX3

0.97	Metaxin-3 isoform A

0.79

GO:0006626

protein targeting to mitochondrion

0.78	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

sp|Q5HYI8|RABL3_HUMAN
Rab-like protein 3
Search

RABL3

0.43	Homogentisate 1,2-dioxygenase

0.44	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.43	GO:0006570	tyrosine metabolic process
0.43	GO:0006558	L-phenylalanine metabolic process
0.43	GO:0009074	aromatic amino acid family catabolic process
0.41	GO:0042737	drug catabolic process
0.36	GO:0055114	oxidation-reduction process

0.64	GO:0001883	purine nucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.64	GO:0032549	ribonucleoside binding
0.61	GO:0003924	GTPase activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004411	homogentisate 1,2-dioxygenase activity
0.39	GO:0042802	identical protein binding

0.44	EC:1.13.11.5	GO:0004411
0.44	KEGG:R02519	GO:0004411

sp|Q5HYJ1|TECRL_HUMAN
Trans-2,3-enoyl-CoA reductase-like
Search

TECRL

0.90	Very-long-chain enoyl-CoA reductase

0.62	GO:0006629	lipid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0072330	monocarboxylic acid biosynthetic process
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:1901362	organic cyclic compound biosynthetic process
0.32	GO:0016070	RNA metabolic process
0.32	GO:0018130	heterocycle biosynthetic process
0.32	GO:0019438	aromatic compound biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.67	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.33	GO:0001104	RNA polymerase II transcription cofactor activity

0.51	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.33	GO:0016592	mediator complex
0.30	GO:0016021	integral component of membrane

0.67

EC:1.3

GO:0016627

sp|Q5HYJ3|FA76B_HUMAN
Protein FAM76B
Search

0.36

GO:0006413

translational initiation

0.36	GO:0003743	translation initiation factor activity
0.36	GO:0005515	protein binding

0.77	GO:0016607	nuclear speck
0.30	GO:0044425	membrane part

sp|Q5HYK3|COQ5_HUMAN
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
Search

COQ5

0.74	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

0.72	GO:0006744	ubiquinone biosynthetic process
0.62	GO:0032259	methylation

0.79	GO:0102005	2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity
0.75	GO:0008425	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
0.34	GO:0005515	protein binding

0.76	GO:0031314	extrinsic component of mitochondrial inner membrane
0.55	GO:0005759	mitochondrial matrix
0.46	GO:0043234	protein complex

0.79

EC:2.1.1.201

GO:0102005

sp|Q5HYK7|SH319_HUMAN
SH3 domain-containing protein 19
Search

SH3D19

0.93	SH3 domain-containing protein 19

0.86	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.70	GO:0007010	cytoskeleton organization
0.69	GO:0022604	regulation of cell morphogenesis
0.34	GO:0043547	positive regulation of GTPase activity
0.33	GO:0035023	regulation of Rho protein signal transduction
0.32	GO:0006886	intracellular protein transport

0.52	GO:0070064	proline-rich region binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.32	GO:0003779	actin binding

0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane

sp|Q5HYK9|ZN667_HUMAN
Zinc finger protein 667
Search

0.41	Zinc finger protein 23

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0035108	limb morphogenesis
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.50	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.47	GO:0031965	nuclear membrane
0.34	GO:0005730	nucleolus
0.33	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q5HYL7|TM196_HUMAN
Transmembrane protein 196
Search

TMEM196

0.79	Transmembrane protein 196

0.30

GO:0044425

membrane part

sp|Q5HYM0|ZC12B_HUMAN
Probable ribonuclease ZC3H12B
Search

ZC3H12B

0.72	Zinc finger CCCH-type containing 12B

0.35

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.53	GO:0046872	metal ion binding
0.35	GO:0004519	endonuclease activity

sp|Q5HYN5|CT451_HUMAN
Cancer/testis antigen family 45 member A1
Search

sp|Q5HYR2|DMRTC_HUMAN
Doublesex- and mab-3-related transcription factor C1
Search

0.97	Doublesex and mab-3 related transcription factor 8.2 isoform a

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0006351	transcription, DNA-templated
0.42	GO:0007548	sex differentiation
0.40	GO:0030154	cell differentiation
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0043565	sequence-specific DNA binding
0.41	GO:0046872	metal ion binding
0.34	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.34	GO:0005840	ribosome

sp|Q5HYW2|NHSL2_HUMAN
NHS-like protein 2
Search

NHSL2

0.94	NHS like 2

0.72	GO:0030154	cell differentiation
0.65	GO:0002088	lens development in camera-type eye

0.59	GO:0016604	nuclear body
0.57	GO:0030054	cell junction
0.55	GO:0005794	Golgi apparatus

sp|Q5HYW3|RGAG4_HUMAN
Retrotransposon gag domain-containing protein 4
Search

RTL5

0.97	Retrotransposon gag domain-containing protein 4

0.56	GO:0006260	DNA replication
0.50	GO:0097659	nucleic acid-templated transcription
0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.47	GO:0010467	gene expression

0.53	GO:0003700	DNA binding transcription factor activity
0.48	GO:0003677	DNA binding

0.53

GO:0005634

nucleus

sp|Q5I0G3|MDH1B_HUMAN
Putative malate dehydrogenase 1B
Search

MDH1B

0.97	Malate dehydrogenase 1B

0.76	GO:0006108	malate metabolic process
0.59	GO:0005975	carbohydrate metabolic process
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0006734	NADH metabolic process
0.50	GO:0006107	oxaloacetate metabolic process
0.46	GO:0006101	citrate metabolic process
0.42	GO:0006091	generation of precursor metabolites and energy
0.35	GO:0045454	cell redox homeostasis

0.74	GO:0016615	malate dehydrogenase activity
0.65	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.36	GO:0008270	zinc ion binding
0.35	GO:0015035	protein disulfide oxidoreductase activity
0.34	GO:0009055	electron transfer activity

0.37

GO:0005737

cytoplasm

0.65

EC:1.1.1

GO:0016616

sp|Q5I0X4|CF226_HUMAN
Uncharacterized protein C6orf226
Search

sp|Q5I0X7|TTC32_HUMAN
Tetratricopeptide repeat protein 32
Search

TTC32

0.97	Novel protein containing a tetratricopeptide repeat

0.63

GO:0042802

identical protein binding

0.30

GO:0044425

membrane part

sp|Q5I7T1|AG10B_HUMAN
Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
Search

0.89	Asparagine-linked glycosylation 10

0.83	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.54	GO:0060117	auditory receptor cell development
0.51	GO:0007605	sensory perception of sound
0.40	GO:1901980	positive regulation of inward rectifier potassium channel activity
0.38	GO:0060050	positive regulation of protein glycosylation
0.38	GO:0006486	protein glycosylation
0.34	GO:0048366	leaf development
0.33	GO:0009651	response to salt stress
0.32	GO:0006468	protein phosphorylation

0.85	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
0.44	GO:0106073	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity
0.37	GO:0015459	potassium channel regulator activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

GO:0004583

sp|Q5IJ48|CRUM2_HUMAN
Protein crumbs homolog 2
Search

0.10	Crumbs 2, cell polarity complex component

0.51	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.50	GO:0055111	ingression involved in gastrulation with mouth forming second
0.48	GO:0014028	notochord formation
0.48	GO:0035090	maintenance of apical/basal cell polarity
0.47	GO:0072358	cardiovascular system development
0.47	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.47	GO:0010470	regulation of gastrulation
0.47	GO:0030513	positive regulation of BMP signaling pathway
0.46	GO:0001707	mesoderm formation
0.46	GO:0001756	somitogenesis

0.69	GO:0005509	calcium ion binding
0.49	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.43	GO:0019899	enzyme binding
0.36	GO:0008061	chitin binding
0.35	GO:0004872	receptor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0045296	cadherin binding
0.33	GO:0030695	GTPase regulator activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0042802	identical protein binding

0.45	GO:0016324	apical plasma membrane
0.41	GO:0043234	protein complex
0.35	GO:0005576	extracellular region
0.34	GO:0005634	nucleus
0.34	GO:0043235	receptor complex
0.33	GO:0015629	actin cytoskeleton
0.33	GO:0031982	vesicle
0.33	GO:0005829	cytosol
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0005887	integral component of plasma membrane

0.34

GO:0004713

sp|Q5J5C9|DB121_HUMAN
Beta-defensin 121
Search

DEFB121

0.61	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium

0.38

GO:0005515

protein binding

0.66	GO:0005576	extracellular region
0.50	GO:0009986	cell surface

sp|Q5J8M3|EMC4_HUMAN
ER membrane protein complex subunit 4
Search

EMC4

0.76	ER membrane protein complex subunit 4

0.50	GO:0034975	protein folding in endoplasmic reticulum
0.39	GO:0006915	apoptotic process

0.59

GO:0072546

ER membrane protein complex

sp|Q5J8X5|M4A13_HUMAN
Membrane-spanning 4-domains subfamily A member 13
Search

MS4A13

0.97	Testis-expressed transmembrane protein 4

0.30

GO:0044425

membrane part

sp|Q5JNZ3|ZN311_HUMAN
Zinc finger protein 311
Search

0.72	Zinc finger protein 311

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.48	GO:0042552	myelination
0.47	GO:0006351	transcription, DNA-templated
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0007219	Notch signaling pathway
0.33	GO:0006468	protein phosphorylation

0.51	GO:0046872	metal ion binding
0.51	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.33	GO:0003682	chromatin binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50

GO:0005634

nucleus

sp|Q5JNZ5|RS26L_HUMAN
Putative 40S ribosomal protein S26-like 1
Search

RPS26

0.68	40S ribosomal protein S26

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.42	GO:0033119	negative regulation of RNA splicing
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.47	GO:0003729	mRNA binding
0.40	GO:0045296	cadherin binding
0.34	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.44	GO:0005844	polysome
0.44	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm

0.34

EC:2.7.10.1

GO:0004714

sp|Q5JPB2|ZN831_HUMAN
Zinc finger protein 831
Search

ZNF831

0.93	Zinc finger protein 831

0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0006366	transcription by RNA polymerase II
0.50	GO:0007275	multicellular organism development
0.45	GO:0007165	signal transduction
0.37	GO:0030154	cell differentiation
0.37	GO:0007398	ectoderm development
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0016358	dendrite development
0.36	GO:0008283	cell proliferation
0.36	GO:0045705	negative regulation of salivary gland boundary specification

0.59	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0043565	sequence-specific DNA binding
0.37	GO:0046872	metal ion binding
0.37	GO:0001105	RNA polymerase II transcription coactivator activity
0.37	GO:0001102	RNA polymerase II activating transcription factor binding
0.35	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.46	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q5JPE7|NOMO2_HUMAN
Nodal modulator 2
Search

NOMO1

0.91	Nodal modulator 2

0.45	GO:1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
0.37	GO:0031648	protein destabilization

0.69	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q5JPF3|AN36C_HUMAN
Ankyrin repeat domain-containing protein 36C
Search

0.82	Ankyrin repeat domain-containing protein 36A

0.57	GO:0007283	spermatogenesis
0.46	GO:0040015	negative regulation of multicellular organism growth
0.45	GO:0060259	regulation of feeding behavior
0.45	GO:0046621	negative regulation of organ growth
0.45	GO:0046627	negative regulation of insulin receptor signaling pathway
0.45	GO:0045599	negative regulation of fat cell differentiation
0.45	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.44	GO:0019217	regulation of fatty acid metabolic process
0.43	GO:0042593	glucose homeostasis
0.30	GO:0065009	regulation of molecular function

0.45	GO:0005515	protein binding
0.30	GO:0098772	molecular function regulator

0.49	GO:0005813	centrosome
0.44	GO:0005884	actin filament
0.41	GO:0005886	plasma membrane
0.37	GO:0005829	cytosol

sp|Q5JPH6|SYEM_HUMAN
Probable glutamate--tRNA ligase, mitochondrial
Search

EARS2

0.95	Glutamyl-tRNA synthetase 2, mitochondrial

0.76	GO:0006424	glutamyl-tRNA aminoacylation
0.56	GO:0070127	tRNA aminoacylation for mitochondrial protein translation
0.37	GO:0006886	intracellular protein transport
0.37	GO:0016192	vesicle-mediated transport

0.77	GO:0004818	glutamate-tRNA ligase activity
0.67	GO:0000049	tRNA binding
0.61	GO:0008270	zinc ion binding
0.60	GO:0050561	glutamate-tRNA(Gln) ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005737	cytoplasm
0.43	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0048475	coated membrane
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0098796	membrane protein complex

0.77

EC:6.1.1.17

GO:0004818

sp|Q5JPI3|CC038_HUMAN
Uncharacterized protein C3orf38
Search

0.76	GO:0043065	positive regulation of apoptotic process
0.47	GO:0006915	apoptotic process

0.36

GO:0003676

nucleic acid binding

0.60	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q5JPI9|MET10_HUMAN
Protein-lysine N-methyltransferase METTL10
Search

0.74	S-adenosyl-L-methionine-dependent methyltransferase (Fragment)

0.69	GO:0018022	peptidyl-lysine methylation
0.41	GO:0016192	vesicle-mediated transport
0.32	GO:2000765	regulation of cytoplasmic translation

0.69

GO:0016279

protein-lysine N-methyltransferase activity

0.53	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016279

sp|Q5JQC4|CT47A_HUMAN
Cancer/testis antigen 47A
Search

CT47B1

0.97	Cancer/testis antigen 47A

0.44	GO:0035950	regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter
0.44	GO:2000879	negative regulation of dipeptide transport
0.44	GO:2000531	regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter
0.43	GO:0016584	nucleosome positioning
0.42	GO:0035567	non-canonical Wnt signaling pathway
0.42	GO:0060070	canonical Wnt signaling pathway
0.42	GO:0051301	cell division
0.42	GO:0010629	negative regulation of gene expression
0.42	GO:0009057	macromolecule catabolic process
0.41	GO:0045491	xylan metabolic process

0.43	GO:0005515	protein binding
0.43	GO:0016746	transferase activity, transferring acyl groups
0.42	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.42	GO:0042813	Wnt-activated receptor activity
0.42	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.42	GO:0031176	endo-1,4-beta-xylanase activity
0.42	GO:0008995	ribonuclease E activity
0.42	GO:0043168	anion binding
0.41	GO:0008144	drug binding
0.41	GO:0036094	small molecule binding

0.42	GO:0043189	H4/H2A histone acetyltransferase complex
0.41	GO:0017053	transcriptional repressor complex
0.40	GO:0044459	plasma membrane part
0.40	GO:0098562	cytoplasmic side of membrane
0.37	GO:0005737	cytoplasm
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.43

GO:0016746

sp|Q5JQC9|AKAP4_HUMAN
A-kinase anchor protein 4
Search

AKAP4

0.97	A-kinase anchoring protein 4

0.70	GO:0044458	motile cilium assembly
0.69	GO:0030317	flagellated sperm motility
0.66	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.58	GO:0010738	regulation of protein kinase A signaling
0.55	GO:0008104	protein localization
0.50	GO:0016310	phosphorylation
0.46	GO:0051234	establishment of localization
0.39	GO:0007338	single fertilization

0.70	GO:0051018	protein kinase A binding
0.52	GO:0016301	kinase activity

0.75	GO:0035686	sperm fibrous sheath
0.73	GO:0097228	sperm principal piece
0.68	GO:0030018	Z disc
0.64	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0001669	acrosomal vesicle
0.39	GO:0005952	cAMP-dependent protein kinase complex
0.37	GO:0005634	nucleus
0.37	GO:0005856	cytoskeleton

sp|Q5JQD4|PYY3_HUMAN
Putative peptide YY-3
Search

PYY

0.96	Peptide YY

0.76	GO:0010469	regulation of receptor activity
0.62	GO:0007631	feeding behavior
0.61	GO:0032098	regulation of appetite
0.59	GO:0007586	digestion
0.57	GO:0007218	neuropeptide signaling pathway
0.54	GO:0007267	cell-cell signaling
0.40	GO:0032096	negative regulation of response to food
0.39	GO:0008283	cell proliferation
0.37	GO:0007010	cytoskeleton organization

0.79	GO:0005179	hormone activity
0.57	GO:0001664	G-protein coupled receptor binding

0.66

GO:0005576

extracellular region

sp|Q5JQF7|CF100_HUMAN
Putative uncharacterized protein encoded by LINC01556
Search

sp|Q5JQF8|PAP1M_HUMAN
Polyadenylate-binding protein 1-like 2
Search

0.54	Poly A-binding protein, cytoplasmic 1 b

0.44	GO:0048096	chromatin-mediated maintenance of transcription
0.43	GO:0001556	oocyte maturation
0.43	GO:0051647	nucleus localization
0.42	GO:0006378	mRNA polyadenylation
0.42	GO:0061013	regulation of mRNA catabolic process
0.40	GO:0043487	regulation of RNA stability
0.40	GO:0061515	myeloid cell development
0.38	GO:1902369	negative regulation of RNA catabolic process
0.38	GO:1903313	positive regulation of mRNA metabolic process
0.37	GO:0045070	positive regulation of viral genome replication

0.59	GO:0003723	RNA binding
0.37	GO:0008022	protein C-terminus binding
0.34	GO:0031370	eukaryotic initiation factor 4G binding
0.34	GO:0043621	protein self-association
0.32	GO:0016491	oxidoreductase activity

0.45	GO:0005737	cytoplasm
0.40	GO:0035770	ribonucleoprotein granule
0.38	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.36	GO:1990124	messenger ribonucleoprotein complex
0.35	GO:0030425	dendrite
0.34	GO:1902494	catalytic complex
0.34	GO:0005844	polysome
0.34	GO:0005925	focal adhesion
0.34	GO:0044446	intracellular organelle part

0.32

GO:0016491

sp|Q5JQS5|OR2BB_HUMAN
Olfactory receptor 2B11
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0005549	odorant binding
0.32	GO:0003676	nucleic acid binding

0.56	GO:0005886	plasma membrane
0.35	GO:0005938	cell cortex
0.33	GO:0000786	nucleosome
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q5JQS6|GSAML_HUMAN
Germinal center-associated signaling and motility-like protein
Search

sp|Q5JR12|PPM1J_HUMAN
Protein phosphatase 1J
Search

sp|Q5JR59|MTUS2_HUMAN
Microtubule-associated tumor suppressor candidate 2
Search

MTUS2

0.92	Microtubule-associated tumor suppressor candidate 2

0.49	GO:0042803	protein homodimerization activity
0.48	GO:0008017	microtubule binding

0.83	GO:0045171	intercellular bridge
0.71	GO:0015630	microtubule cytoskeleton
0.47	GO:0099513	polymeric cytoskeletal fiber
0.43	GO:0005634	nucleus
0.40	GO:0044444	cytoplasmic part

sp|Q5JR98|TC1D4_HUMAN
Tctex1 domain-containing protein 4
Search

TCTEX1D4

0.97	Tctex1 domain-containing protein 4

0.85

GO:0008157

protein phosphatase 1 binding

0.85	GO:0036126	sperm flagellum
0.84	GO:0001669	acrosomal vesicle
0.82	GO:0005930	axoneme
0.76	GO:0005815	microtubule organizing center
0.61	GO:0005634	nucleus

sp|Q5JRA6|MIA3_HUMAN
Melanoma inhibitory activity protein 3
Search

MIA3

0.82	Melanoma inhibitory activity protein 3

0.83	GO:0090110	cargo loading into COPII-coated vesicle
0.78	GO:0002687	positive regulation of leukocyte migration
0.76	GO:0007162	negative regulation of cell adhesion
0.76	GO:0030336	negative regulation of cell migration
0.73	GO:0042060	wound healing
0.73	GO:0042953	lipoprotein transport
0.72	GO:0006887	exocytosis
0.43	GO:0043687	post-translational protein modification
0.43	GO:0002063	chondrocyte development
0.42	GO:0030501	positive regulation of bone mineralization

0.73	GO:0042954	lipoprotein transporter activity
0.38	GO:0005515	protein binding

0.81	GO:0070971	endoplasmic reticulum exit site
0.69	GO:0000139	Golgi membrane
0.67	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|Q5JRC9|FA47A_HUMAN
Protein FAM47A
Search

sp|Q5JRK9|GGEE3_HUMAN
Putative G antigen family E member 3
Search

0.88	PAGE family member 5

sp|Q5JRM2|CX066_HUMAN
Uncharacterized protein CXorf66
Search

0.40	40S ribosomal protein SA

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64

GO:0003735

structural constituent of ribosome

0.61

GO:0005840

ribosome

sp|Q5JRS4|O10J3_HUMAN
Olfactory receptor 10J3
Search

0.40	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0007210	serotonin receptor signaling pathway
0.34	GO:0007338	single fertilization

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.38	GO:0099589	serotonin receptor activity
0.37	GO:0030594	neurotransmitter receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q5JRV8|T255A_HUMAN
Transmembrane protein 255A
Search

TMEM255A

0.96	Transmembrane protein 255A

0.30

GO:0044425

membrane part

sp|Q5JRX3|PREP_HUMAN
Presequence protease, mitochondrial
Search

PITRM1

0.97	Pitrilysin metalloproteinase 1

0.60

GO:0006508

proteolysis

0.58	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding

0.61	GO:0005759	mitochondrial matrix
0.30	GO:0044425	membrane part

0.58

GO:0004222

sp|Q5JS13|RGPS1_HUMAN
Ras-specific guanine nucleotide-releasing factor RalGPS1
Search

RALGPS1

0.85	Ral GEF with PH domain and SH3 binding motif 1

0.77	GO:0032485	regulation of Ral protein signal transduction
0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.67	GO:0017160	Ral GTPase binding

0.45

GO:0005622

intracellular

sp|Q5JS37|NHLC3_HUMAN
NHL repeat-containing protein 3
Search

NHLRC3

0.97	NHL repeat-containing protein 3

0.49

GO:0043312

neutrophil degranulation

0.52	GO:0070062	extracellular exosome
0.50	GO:0035578	azurophil granule lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q5JS54|PSMG4_HUMAN
Proteasome assembly chaperone 4
Search

PSMG4

0.95	Proteasome assembly chaperone 4

0.77

GO:0043248

proteasome assembly

0.58	GO:1905369	endopeptidase complex
0.49	GO:0043234	protein complex
0.40	GO:0044424	intracellular part
0.30	GO:0031224	intrinsic component of membrane

sp|Q5JSH3|WDR44_HUMAN
WD repeat-containing protein 44
Search

WDR44

0.91	WD repeat-containing protein 44

0.38	GO:0030334	regulation of cell migration
0.34	GO:0019221	cytokine-mediated signaling pathway
0.34	GO:0007264	small GTPase mediated signal transduction
0.34	GO:0016539	intein-mediated protein splicing
0.33	GO:0065009	regulation of molecular function

0.38	GO:0017137	Rab GTPase binding
0.35	GO:0004896	cytokine receptor activity
0.34	GO:0005085	guanyl-nucleotide exchange factor activity

0.71	GO:0005794	Golgi apparatus
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0010008	endosome membrane
0.44	GO:0005829	cytosol
0.37	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

sp|Q5JSJ4|INT6L_HUMAN
Integrator complex subunit 6-like
Search

INTS6L

0.76	Integrator complex subunit 6 like

0.75	GO:0016180	snRNA processing
0.42	GO:0042795	snRNA transcription by RNA polymerase II
0.36	GO:0007165	signal transduction

0.38	GO:0004888	transmembrane signaling receptor activity
0.37	GO:0005515	protein binding

0.76	GO:0032039	integrator complex
0.68	GO:0015629	actin cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q5JSL3|DOC11_HUMAN
Dedicator of cytokinesis protein 11
Search

DOCK11

0.92	Dedicator of cytokinesis protein 9

0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.53	GO:0002315	marginal zone B cell differentiation
0.52	GO:0001782	B cell homeostasis
0.51	GO:0051491	positive regulation of filopodium assembly
0.35	GO:0007596	blood coagulation
0.33	GO:0019221	cytokine-mediated signaling pathway

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.47	GO:0017048	Rho GTPase binding
0.33	GO:0004896	cytokine receptor activity

0.45	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q5JSP0|FGD3_HUMAN
FYVE, RhoGEF and PH domain-containing protein 3
Search

FGD3

0.97	FYVE, RhoGEF and PH domain-containing protein 3

0.75	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.47	GO:0046847	filopodium assembly
0.42	GO:0030036	actin cytoskeleton organization
0.40	GO:0008360	regulation of cell shape
0.36	GO:0043065	positive regulation of apoptotic process
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0009887	animal organ morphogenesis

0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.52	GO:0046872	metal ion binding

0.44	GO:0001726	ruffle
0.43	GO:0030027	lamellipodium
0.41	GO:0005794	Golgi apparatus
0.38	GO:0005856	cytoskeleton
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q5JSQ8|KHDCL_HUMAN
Putative KHDC1-like protein
Search

0.97	KH like proteiny domain-containing protein 1

0.41	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.39	GO:0006915	apoptotic process

0.59	GO:0003723	RNA binding
0.42	GO:0042802	identical protein binding

0.35	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q5JSS6|MEIG1_HUMAN
Meiosis expressed gene 1 protein homolog
Search

MEIG1

0.97	Meiosis/spermiogenesis associated 1

0.61	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q5JST6|EFHC2_HUMAN
EF-hand domain-containing family member C2
Search

EFHC2

0.82	EF-hand domain-containing family member C2

0.58	GO:1990823	response to leukemia inhibitory factor
0.54	GO:0071345	cellular response to cytokine stimulus

0.65	GO:0005509	calcium ion binding
0.41	GO:0005515	protein binding

0.41	GO:0005615	extracellular space
0.30	GO:0005623	cell

sp|Q5JSZ5|PRC2B_HUMAN
Protein PRRC2B
Search

PRRC2B

0.97	Proline rich coiled-coil 2B

0.70

GO:0030154

cell differentiation

0.44

GO:0003723

RNA binding

sp|Q5JT25|RAB41_HUMAN
Ras-related protein Rab-41
Search

0.81	Putative rab subfamily protein of small gtpase

0.45	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.45	GO:0006891	intra-Golgi vesicle-mediated transport
0.45	GO:0042147	retrograde transport, endosome to Golgi
0.39	GO:0060471	cortical granule exocytosis
0.36	GO:1904515	positive regulation of TORC2 signaling
0.35	GO:0015031	protein transport
0.34	GO:0010452	histone H3-K36 methylation
0.34	GO:0018027	peptidyl-lysine dimethylation
0.34	GO:0018026	peptidyl-lysine monomethylation
0.34	GO:0018023	peptidyl-lysine trimethylation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031489	myosin V binding
0.34	GO:0046975	histone methyltransferase activity (H3-K36 specific)
0.34	GO:0003713	transcription coactivator activity

0.47	GO:0005794	Golgi apparatus
0.42	GO:0005829	cytosol
0.38	GO:0060473	cortical granule
0.37	GO:0031984	organelle subcompartment
0.36	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0098588	bounding membrane of organelle
0.32	GO:0005886	plasma membrane

sp|Q5JT78|CA137_HUMAN
Putative uncharacterized protein C1orf137
Search

sp|Q5JT82|KLF17_HUMAN
Krueppel-like factor 17
Search

KLF17

0.97	Kruppel like factor 17

0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0048523	negative regulation of cellular process
0.36	GO:0007276	gamete generation
0.35	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation
0.35	GO:0010605	negative regulation of macromolecule metabolic process
0.35	GO:2000317	negative regulation of T-helper 17 type immune response
0.35	GO:0010604	positive regulation of macromolecule metabolic process

0.51	GO:0003676	nucleic acid binding
0.41	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0005515	protein binding
0.32	GO:0004984	olfactory receptor activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003735	structural constituent of ribosome

0.42	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.33	GO:0015630	microtubule cytoskeleton
0.32	GO:0005840	ribosome
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008168

sp|Q5JTB6|PLAC9_HUMAN
Placenta-specific protein 9
Search

PLAC9

0.97	Placenta-specific protein 9

0.47

GO:0005515

protein binding

0.63	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q5JTC6|AMER1_HUMAN
APC membrane recruitment protein 1
Search

AMER1

0.92	APC membrane recruitment protein 1

0.84	GO:2001012	mesenchymal cell differentiation involved in renal system development
0.83	GO:0072074	kidney mesenchyme development
0.82	GO:0060828	regulation of canonical Wnt signaling pathway
0.81	GO:0030177	positive regulation of Wnt signaling pathway
0.81	GO:0030178	negative regulation of Wnt signaling pathway
0.81	GO:0060612	adipose tissue development
0.80	GO:0061005	cell differentiation involved in kidney development
0.79	GO:0031398	positive regulation of protein ubiquitination
0.78	GO:1903364	positive regulation of cellular protein catabolic process
0.77	GO:0060348	bone development

0.87	GO:1904713	beta-catenin destruction complex binding
0.85	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.83	GO:0008013	beta-catenin binding

0.75	GO:0016604	nuclear body
0.56	GO:0005886	plasma membrane
0.40	GO:0005829	cytosol

sp|Q5JTD0|TJAP1_HUMAN
Tight junction-associated protein 1
Search

TJAP1

0.96	Tight junction-associated protein 1

0.55

GO:0007030

Golgi organization

0.35

GO:0005515

protein binding

0.81	GO:0005923	bicellular tight junction
0.54	GO:0005802	trans-Golgi network
0.52	GO:0005768	endosome
0.42	GO:0005886	plasma membrane

sp|Q5JTD7|LRC73_HUMAN
Leucine-rich repeat-containing protein 73
Search

LRRC73

0.97	Leucine-rich repeat-containing protein 73

sp|Q5JTH9|RRP12_HUMAN
RRP12-like protein
Search

RRP12

0.97	Ribosomal RNA processing 12 homolog

0.38

GO:0007165

signal transduction

0.37	GO:0003723	RNA binding
0.34	GO:0004930	G-protein coupled receptor activity

0.70	GO:0005730	nucleolus
0.45	GO:0031965	nuclear membrane
0.30	GO:0044425	membrane part

sp|Q5JTJ3|COA6_HUMAN
Cytochrome c oxidase assembly factor 6 homolog
Search

COA6

0.87	Molybdenum cofactor synthesis protein cinnamon

0.45	GO:0042774	plasma membrane ATP synthesis coupled electron transport
0.41	GO:0008535	respiratory chain complex IV assembly
0.37	GO:1902600	hydrogen ion transmembrane transport
0.37	GO:0007507	heart development
0.34	GO:0015031	protein transport

0.39	GO:0005507	copper ion binding
0.38	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.38	GO:0015002	heme-copper terminal oxidase activity
0.37	GO:0015078	hydrogen ion transmembrane transporter activity
0.37	GO:0009055	electron transfer activity
0.35	GO:0005515	protein binding
0.35	GO:0003723	RNA binding

0.61	GO:0005739	mitochondrion
0.41	GO:0031970	organelle envelope lumen
0.40	GO:0072492	host cell mitochondrial intermembrane space
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:1.9.3

GO:0016676

sp|Q5JTN6|WDR38_HUMAN
WD repeat-containing protein 38
Search

WDR38

0.93	WD repeat-containing protein 38

0.74	GO:0002244	hematopoietic progenitor cell differentiation
0.45	GO:0006468	protein phosphorylation
0.34	GO:0042254	ribosome biogenesis
0.34	GO:0072486	signal transduction involved in spindle assembly checkpoint
0.34	GO:0072477	signal transduction involved in mitotic spindle checkpoint
0.34	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0007094	mitotic spindle assembly checkpoint
0.34	GO:0070925	organelle assembly
0.34	GO:0009116	nucleoside metabolic process
0.34	GO:0034613	cellular protein localization

0.45	GO:0004672	protein kinase activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008144	drug binding
0.36	GO:0043565	sequence-specific DNA binding
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.36	GO:0005730	nucleolus
0.35	GO:0000242	pericentriolar material
0.34	GO:0036064	ciliary basal body
0.34	GO:0005814	centriole
0.34	GO:1990298	bub1-bub3 complex
0.34	GO:0045177	apical part of cell
0.34	GO:0000922	spindle pole
0.34	GO:0000778	condensed nuclear chromosome kinetochore
0.30	GO:0016020	membrane

sp|Q5JTV8|TOIP1_HUMAN
Torsin-1A-interacting protein 1
Search

TOR1AIP1

0.96	Torsin A interacting protein 1

0.67	GO:0006998	nuclear envelope organization
0.66	GO:0032781	positive regulation of ATPase activity
0.65	GO:0034504	protein localization to nucleus
0.49	GO:0007029	endoplasmic reticulum organization

0.68	GO:0051117	ATPase binding
0.66	GO:0001671	ATPase activator activity
0.54	GO:0008092	cytoskeletal protein binding
0.44	GO:0005521	lamin binding

0.63	GO:0031965	nuclear membrane
0.45	GO:0005783	endoplasmic reticulum
0.40	GO:0019866	organelle inner membrane
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|Q5JTW2|CEP78_HUMAN
Centrosomal protein of 78 kDa
Search

CEP78

0.46	Phosphoserine aminotransferase

0.72	GO:0044782	cilium organization
0.42	GO:0000086	G2/M transition of mitotic cell cycle
0.41	GO:0006564	L-serine biosynthetic process
0.41	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.40	GO:0140056	organelle localization by membrane tethering
0.40	GO:0120031	plasma membrane bounded cell projection assembly
0.39	GO:0070925	organelle assembly
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.42	GO:0004648	O-phospho-L-serine:2-oxoglutarate aminotransferase activity
0.34	GO:0004871	signal transducer activity

0.77	GO:0005813	centrosome
0.75	GO:0036064	ciliary basal body
0.45	GO:0005814	centriole
0.38	GO:0005829	cytosol
0.36	GO:1905360	GTPase complex
0.36	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0098797	plasma membrane protein complex

0.42

EC:2.6.1.52

GO:0004648

sp|Q5JTY5|CBWD3_HUMAN
COBW domain-containing protein 3
Search

0.71	Cobalamin synthase W domain-containing protein 3

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding

sp|Q5JTZ5|CI152_HUMAN
Uncharacterized protein C9orf152
Search

sp|Q5JTZ9|SYAM_HUMAN
Alanine--tRNA ligase, mitochondrial
Search

AARS2

0.44	LOW QUALITY PROTEIN: alanine--tRNA ligase, mitochondrial

0.78	GO:0006419	alanyl-tRNA aminoacylation
0.63	GO:0070127	tRNA aminoacylation for mitochondrial protein translation
0.55	GO:0033108	mitochondrial respiratory chain complex assembly
0.43	GO:0006400	tRNA modification
0.33	GO:0046686	response to cadmium ion
0.33	GO:0002181	cytoplasmic translation
0.33	GO:0006413	translational initiation

0.78	GO:0004813	alanine-tRNA ligase activity
0.64	GO:0000049	tRNA binding
0.58	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0016597	amino acid binding
0.33	GO:0003743	translation initiation factor activity

0.49	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.33	GO:0009507	chloroplast
0.30	GO:0016020	membrane

0.78

EC:6.1.1.7

GO:0004813

sp|Q5JU00|TCTE1_HUMAN
T-complex-associated testis-expressed protein 1
Search

TCTE1

0.97	T-complex-associated testis-expressed protein 1

0.30

GO:0044425

membrane part

sp|Q5JU67|CF157_HUMAN
Cilia- and flagella-associated protein 157
Search

CFAP157

0.97	Cilia- and flagella-associated protein 157

0.85	GO:0007288	sperm axoneme assembly
0.38	GO:0006904	vesicle docking involved in exocytosis
0.34	GO:0035735	intraciliary transport involved in cilium assembly
0.33	GO:0010564	regulation of cell cycle process
0.33	GO:0021591	ventricular system development
0.33	GO:0051310	metaphase plate congression
0.33	GO:0001822	kidney development
0.33	GO:0070507	regulation of microtubule cytoskeleton organization
0.32	GO:0007346	regulation of mitotic cell cycle
0.32	GO:0000278	mitotic cell cycle

0.71	GO:0008017	microtubule binding
0.33	GO:0070840	dynein complex binding
0.33	GO:0008022	protein C-terminus binding
0.32	GO:0042803	protein homodimerization activity
0.32	GO:0008134	transcription factor binding

0.79	GO:0036064	ciliary basal body
0.65	GO:0005829	cytosol
0.53	GO:0043231	intracellular membrane-bounded organelle
0.53	GO:0005886	plasma membrane
0.39	GO:0031514	motile cilium
0.33	GO:0034451	centriolar satellite
0.33	GO:0097539	ciliary transition fiber
0.33	GO:0030496	midbody
0.33	GO:0000940	condensed chromosome outer kinetochore
0.33	GO:0000922	spindle pole

sp|Q5JU69|TOR2A_HUMAN
Torsin-2A
Search

TOR2A

0.97	Prosalusin

0.72	GO:0051085	chaperone cofactor-dependent protein refolding
0.60	GO:0072321	chaperone-mediated protein transport
0.58	GO:0045104	intermediate filament cytoskeleton organization
0.58	GO:0006998	nuclear envelope organization
0.57	GO:0048489	synaptic vesicle transport
0.56	GO:0051260	protein homooligomerization
0.54	GO:0031175	neuron projection development
0.51	GO:0007155	cell adhesion
0.39	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.39	GO:0051940	regulation of catecholamine uptake involved in synaptic transmission

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008092	cytoskeletal protein binding
0.51	GO:0051082	unfolded protein binding
0.38	GO:0051787	misfolded protein binding
0.37	GO:0098772	molecular function regulator
0.36	GO:0005102	receptor binding
0.35	GO:0051020	GTPase binding

0.73	GO:0005788	endoplasmic reticulum lumen
0.53	GO:0005635	nuclear envelope
0.53	GO:0045202	synapse
0.38	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.37	GO:0070382	exocytic vesicle
0.37	GO:0005829	cytosol
0.37	GO:0097458	neuron part
0.36	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.35

GO:0016887

sp|Q5JU85|IQEC2_HUMAN
IQ motif and SEC7 domain-containing protein 2
Search

IQSEC2

0.89	IQ motif and SEC7 domain-containing protein 2

0.80	GO:0032012	regulation of ARF protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.47	GO:0030036	actin cytoskeleton organization
0.37	GO:1900454	positive regulation of long term synaptic depression
0.36	GO:0001946	lymphangiogenesis
0.36	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.36	GO:0001525	angiogenesis

0.80	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.33	GO:0008289	lipid binding

0.35	GO:0005730	nucleolus
0.34	GO:0005737	cytoplasm

sp|Q5JUK2|SOLH1_HUMAN
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
Search

SOHLH1

0.96	Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

0.82	GO:0048477	oogenesis
0.80	GO:0007283	spermatogenesis
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0006366	transcription by RNA polymerase II
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.46	GO:0007275	multicellular organism development

0.66	GO:0046983	protein dimerization activity
0.55	GO:0001046	core promoter sequence-specific DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|Q5JUK3|KCNT1_HUMAN
Potassium channel subfamily T member 1
Search

KCNT1

0.96	Potassium sodium-activated channel subfamily T member 1

0.71	GO:0006813	potassium ion transport
0.41	GO:0098662	inorganic cation transmembrane transport
0.30	GO:0009987	cellular process

0.47	GO:0015269	calcium-activated potassium channel activity
0.46	GO:0005249	voltage-gated potassium channel activity

0.46

GO:0008076

voltage-gated potassium channel complex

sp|Q5JUK9|PAGE3_HUMAN
P antigen family member 3
Search

PAGE3

0.97	P antigen family member 3

0.63

GO:0005515

protein binding

sp|Q5JUQ0|FA78A_HUMAN
Protein FAM78A
Search

sp|Q5JUR7|TEX30_HUMAN
Testis-expressed protein 30
Search

TEX30

0.97	Testis-expressed protein 30

0.35	GO:0090630	activation of GTPase activity
0.34	GO:0051056	regulation of small GTPase mediated signal transduction

0.51	GO:0016787	hydrolase activity
0.34	GO:0005096	GTPase activator activity

0.30

GO:0031224

intrinsic component of membrane

0.51