Queries 14001 to 15000

GO:0004252

sp|P17074|RS19_RAT
40S ribosomal protein S19
Search

RPS19

0.55	Ribosomal protein S19

0.60	GO:0006518	peptide metabolic process
0.60	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.56	GO:0000028	ribosomal small subunit assembly
0.54	GO:0030218	erythrocyte differentiation
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.54	GO:0060265	positive regulation of respiratory burst involved in inflammatory response
0.53	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.53	GO:0009059	macromolecule biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.51	GO:0017134	fibroblast growth factor binding
0.48	GO:0019901	protein kinase binding
0.46	GO:0042803	protein homodimerization activity
0.36	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0031369	translation initiation factor binding
0.34	GO:0046872	metal ion binding
0.34	GO:0032403	protein complex binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.46	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005581	collagen trimer
0.34	GO:0030008	TRAPP complex
0.30	GO:0016020	membrane

0.34	EC:1.8.1.9	GO:0004791
0.34	KEGG:R02016	GO:0004791

sp|P17077|RL9_RAT
60S ribosomal protein L9
Search

RPL9

0.72	Ribosomal protein L9, pseudogene 6

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:1990090	cellular response to nerve growth factor stimulus
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P17078|RL35_RAT
60S ribosomal protein L35
Search

RPL35

0.76	Ribosomal protein L35

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.47	GO:0042273	ribosomal large subunit biogenesis
0.45	GO:0016072	rRNA metabolic process
0.41	GO:0030218	erythrocyte differentiation
0.40	GO:0043009	chordate embryonic development
0.39	GO:0051726	regulation of cell cycle
0.35	GO:0071493	cellular response to UV-B

0.62	GO:0003735	structural constituent of ribosome
0.47	GO:0003729	mRNA binding
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005634	nucleus
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P17084|COL_RAT
Colipase
Search

CLPS

0.97	Pancreatic colipase

0.84	GO:0007586	digestion
0.73	GO:0043085	positive regulation of catalytic activity
0.72	GO:0016042	lipid catabolic process
0.57	GO:0032094	response to food
0.38	GO:0001523	retinoid metabolic process
0.38	GO:0009791	post-embryonic development

0.75

GO:0008047

enzyme activator activity

0.66	GO:0005576	extracellular region
0.39	GO:0031982	vesicle

sp|P17105|IP3KA_RAT
Inositol-trisphosphate 3-kinase A
Search

ITPKA

0.53	Inositol-trisphosphate 3-kinase A

0.86	GO:0097062	dendritic spine maintenance
0.86	GO:0061003	positive regulation of dendritic spine morphogenesis
0.83	GO:0032958	inositol phosphate biosynthetic process
0.81	GO:0048167	regulation of synaptic plasticity
0.76	GO:0006020	inositol metabolic process
0.71	GO:0030036	actin cytoskeleton organization
0.61	GO:0006468	protein phosphorylation
0.47	GO:0007165	signal transduction

0.86	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity
0.83	GO:0048365	Rac GTPase binding
0.80	GO:0004683	calmodulin-dependent protein kinase activity
0.76	GO:0005516	calmodulin binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0043197	dendritic spine
0.51	GO:0005829	cytosol

0.86	EC:2.7.1.127	GO:0008440
0.86	KEGG:R03433	GO:0008440

sp|P17108|IL2_RAT
Interleukin-2
Search

IL2

0.96	Interleukin-2

0.83	GO:0002250	adaptive immune response
0.76	GO:0010469	regulation of receptor activity
0.65	GO:0046013	regulation of T cell homeostatic proliferation
0.64	GO:0051024	positive regulation of immunoglobulin secretion
0.64	GO:0002903	negative regulation of B cell apoptotic process
0.64	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.63	GO:2000320	negative regulation of T-helper 17 cell differentiation
0.63	GO:0042104	positive regulation of activated T cell proliferation
0.63	GO:0032740	positive regulation of interleukin-17 production
0.62	GO:0038034	signal transduction in absence of ligand

0.87	GO:0005134	interleukin-2 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.43	GO:0031851	kappa-type opioid receptor binding
0.42	GO:0043208	glycosphingolipid binding
0.38	GO:0030246	carbohydrate binding
0.38	GO:0019209	kinase activator activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.73	GO:0005615	extracellular space
0.32	GO:0005622	intracellular

sp|P17136|RSMB_RAT
Small nuclear ribonucleoprotein-associated protein B (Fragment)
Search

SNRPB

0.85	Small nuclear ribonucleoprotein-associated proteins B and B'

0.51	GO:0000398	mRNA splicing, via spliceosome
0.47	GO:0022618	ribonucleoprotein complex assembly
0.45	GO:0008213	protein alkylation
0.43	GO:0043414	macromolecule methylation
0.36	GO:0008334	histone mRNA metabolic process
0.36	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0007420	brain development
0.35	GO:0051170	nuclear import
0.34	GO:0009725	response to hormone

0.57	GO:0003723	RNA binding
0.37	GO:1990447	U2 snRNP binding
0.36	GO:1990446	U1 snRNP binding
0.34	GO:0005515	protein binding

0.61	GO:0030529	intracellular ribonucleoprotein complex
0.59	GO:0005634	nucleus
0.58	GO:0019013	viral nucleocapsid
0.53	GO:0034709	methylosome
0.52	GO:0034719	SMN-Sm protein complex
0.45	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome

sp|P17164|FUCO_RAT
Tissue alpha-L-fucosidase
Search

FUCA1

0.89	Tissue alpha-L-fucosidase

0.79	GO:0006004	fucose metabolic process
0.57	GO:0016139	glycoside catabolic process
0.37	GO:0019377	glycolipid catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006027	glycosaminoglycan catabolic process

0.80	GO:0004560	alpha-L-fucosidase activity
0.35	GO:0004419	hydroxymethylglutaryl-CoA lyase activity
0.34	GO:0030246	carbohydrate binding
0.32	GO:0003676	nucleic acid binding

0.40	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:3.2.1.51	GO:0004560
0.35	KEGG:R01360	GO:0004419

sp|P17178|CP27A_RAT
Sterol 26-hydroxylase, mitochondrial
Search

CYP27A1

0.96	Sterol 26-hydroxylase, mitochondrial

0.53	GO:0055114	oxidation-reduction process
0.37	GO:0036378	calcitriol biosynthetic process from calciol
0.37	GO:0016125	sterol metabolic process
0.36	GO:0006706	steroid catabolic process
0.36	GO:0006699	bile acid biosynthetic process
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.37	GO:0030343	vitamin D3 25-hydroxylase activity
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P17209|MYL4_RAT
Myosin light chain 4
Search

MYL4

0.95	Myosin light polypeptide 3

0.64	GO:0002026	regulation of the force of heart contraction
0.62	GO:0060048	cardiac muscle contraction
0.53	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.52	GO:0006942	regulation of striated muscle contraction
0.52	GO:0032781	positive regulation of ATPase activity
0.38	GO:0007519	skeletal muscle tissue development
0.37	GO:0030049	muscle filament sliding
0.35	GO:0060055	angiogenesis involved in wound healing
0.35	GO:0070527	platelet aggregation
0.35	GO:0007044	cell-substrate junction assembly

0.70	GO:0005509	calcium ion binding
0.62	GO:0003785	actin monomer binding
0.50	GO:0051015	actin filament binding
0.37	GO:0032038	myosin II heavy chain binding
0.37	GO:0003774	motor activity
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004872	receptor activity

0.62	GO:0031672	A band
0.51	GO:0031674	I band
0.42	GO:0016459	myosin complex
0.34	GO:0005829	cytosol
0.34	GO:0008305	integrin complex

0.33

GO:0004252

sp|P17220|PSA2_RAT
Proteasome subunit alpha type-2
Search

PSMA2

0.48	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.67	GO:0043632	modification-dependent macromolecule catabolic process
0.35	GO:0009615	response to virus
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.77	GO:0004298	threonine-type endopeptidase activity
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0005515	protein binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.57	GO:0005634	nucleus
0.51	GO:0000932	P-body
0.38	GO:0070062	extracellular exosome
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0101002	ficolin-1-rich granule
0.35	GO:0031983	vesicle lumen
0.34	GO:0005829	cytosol
0.34	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.77

GO:0004298

sp|P17246|TGFB1_RAT
Transforming growth factor beta-1
Search

TGFB1

0.92	Transforming growth factor beta

0.79	GO:0016049	cell growth
0.76	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.76	GO:1901664	regulation of NAD+ ADP-ribosyltransferase activity
0.76	GO:0043932	ossification involved in bone remodeling
0.75	GO:0048298	positive regulation of isotype switching to IgA isotypes
0.75	GO:0010936	negative regulation of macrophage cytokine production
0.75	GO:0007182	common-partner SMAD protein phosphorylation
0.74	GO:0007183	SMAD protein complex assembly
0.74	GO:0010763	positive regulation of fibroblast migration
0.74	GO:0032740	positive regulation of interleukin-17 production

0.84	GO:0005160	transforming growth factor beta receptor binding
0.75	GO:0008083	growth factor activity
0.71	GO:0003823	antigen binding
0.58	GO:0043539	protein serine/threonine kinase activator activity
0.53	GO:0042802	identical protein binding
0.51	GO:0019899	enzyme binding
0.48	GO:0005125	cytokine activity
0.41	GO:0047485	protein N-terminus binding
0.39	GO:0046982	protein heterodimerization activity
0.35	GO:0050431	transforming growth factor beta binding

0.72	GO:0005615	extracellular space
0.63	GO:0009986	cell surface
0.60	GO:0005902	microvillus
0.56	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.39	GO:0097708	intracellular vesicle
0.38	GO:0012505	endomembrane system

sp|P17256|KIME_RAT
Mevalonate kinase
Search

MVK

0.59	Mevalonate kinase

0.83	GO:0006695	cholesterol biosynthetic process
0.80	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway
0.57	GO:0050728	negative regulation of inflammatory response
0.57	GO:0016310	phosphorylation
0.38	GO:0045540	regulation of cholesterol biosynthetic process
0.35	GO:0017148	negative regulation of translation
0.34	GO:0010142	farnesyl diphosphate biosynthetic process, mevalonate pathway
0.33	GO:0006696	ergosterol biosynthetic process

0.81	GO:0004496	mevalonate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.36	GO:1990825	sequence-specific mRNA binding
0.36	GO:0005534	galactose binding

0.50	GO:0005829	cytosol
0.38	GO:0005777	peroxisome
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81	EC:2.7.1.36	GO:0004496
0.81	KEGG:R02245	GO:0004496

sp|P17267|IF_RAT
Gastric intrinsic factor
Search

GIF

0.97	Gastric intrinsic factor

0.78	GO:0015889	cobalamin transport
0.45	GO:0006824	cobalt ion transport
0.39	GO:0009235	cobalamin metabolic process
0.38	GO:0043043	peptide biosynthetic process
0.37	GO:0044267	cellular protein metabolic process
0.36	GO:0010467	gene expression
0.36	GO:0009059	macromolecule biosynthetic process
0.35	GO:0006886	intracellular protein transport
0.35	GO:0016192	vesicle-mediated transport

0.75	GO:0031419	cobalamin binding
0.39	GO:0003735	structural constituent of ribosome
0.36	GO:0019843	rRNA binding

0.71	GO:0005902	microvillus
0.68	GO:0016324	apical plasma membrane
0.63	GO:0005768	endosome
0.62	GO:0005615	extracellular space
0.39	GO:0043202	lysosomal lumen
0.38	GO:0005840	ribosome
0.36	GO:0030117	membrane coat

sp|P17325|JUN_RAT
Transcription factor AP-1
Search

JUN

0.89	Transcription factor jun-B

0.57	GO:0035026	leading edge cell differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0001774	microglial cell activation
0.56	GO:0046686	response to cadmium ion
0.56	GO:0010468	regulation of gene expression
0.56	GO:0061029	eyelid development in camera-type eye
0.56	GO:0031953	negative regulation of protein autophosphorylation
0.56	GO:1903131	mononuclear cell differentiation
0.56	GO:0035994	response to muscle stretch

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0070412	R-SMAD binding
0.55	GO:0003677	DNA binding
0.54	GO:0001102	RNA polymerase II activating transcription factor binding
0.53	GO:0003713	transcription coactivator activity
0.53	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0003682	chromatin binding
0.50	GO:0005096	GTPase activator activity
0.49	GO:0042803	protein homodimerization activity

0.56	GO:0035976	transcription factor AP-1 complex
0.53	GO:0005719	nuclear euchromatin
0.52	GO:0017053	transcriptional repressor complex
0.47	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.33	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P17425|HMCS1_RAT
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
Search

HMGCS1

0.67	3-hydroxy-3-methylglutaryl coenzyme A synthase

0.78	GO:0016126	sterol biosynthetic process
0.71	GO:0008299	isoprenoid biosynthetic process
0.45	GO:0014003	oligodendrocyte development
0.36	GO:0033197	response to vitamin E
0.35	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.35	GO:0071397	cellular response to cholesterol
0.35	GO:0009645	response to low light intensity stimulus
0.35	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.35	GO:0046690	response to tellurium ion
0.35	GO:0008584	male gonad development

0.83	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.35	GO:0008009	chemokine activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0043177	organic acid binding
0.33	GO:0016853	isomerase activity
0.32	GO:0008144	drug binding

0.33	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.83	EC:2.3.3.10	GO:0004421
0.83	KEGG:R01978	GO:0004421

sp|P17431|TISB_RAT
mRNA decay activator protein ZFP36L1
Search

ZFP36L1

0.96	ZFP36 ring finger protein like 1

0.76	GO:1904582	positive regulation of intracellular mRNA localization
0.75	GO:0061158	3'-UTR-mediated mRNA destabilization
0.75	GO:0097403	cellular response to raffinose
0.75	GO:1902172	regulation of keratinocyte apoptotic process
0.74	GO:0045657	positive regulation of monocyte differentiation
0.74	GO:0045647	negative regulation of erythrocyte differentiation
0.73	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.73	GO:0003343	septum transversum development
0.72	GO:0070371	ERK1 and ERK2 cascade
0.72	GO:0045616	regulation of keratinocyte differentiation

0.73	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.72	GO:0071889	14-3-3 protein binding
0.54	GO:0046872	metal ion binding

0.66	GO:0000932	P-body
0.52	GO:0005634	nucleus
0.46	GO:0005829	cytosol

sp|P17438|PRPH2_RAT
Peripherin-2
Search

PRPH2

0.97	Retinal degeneration, slow (Retinitis pigmentosa 7)

0.78	GO:0007601	visual perception
0.55	GO:0060041	retina development in camera-type eye
0.44	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0007155	cell adhesion
0.35	GO:0009645	response to low light intensity stimulus
0.35	GO:1903525	regulation of membrane tubulation
0.35	GO:0051289	protein homotetramerization
0.34	GO:0051258	protein polymerization

0.34	GO:0042803	protein homodimerization activity
0.34	GO:0015631	tubulin binding

0.56	GO:0001750	photoreceptor outer segment
0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0055037	recycling endosome
0.34	GO:0005795	Golgi stack
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0043234	protein complex

sp|P17475|A1AT_RAT
Alpha-1-antiproteinase
Search

SERPINA1

0.88	Hibernation-specific plasma protein HP-55

0.56	GO:0010951	negative regulation of endopeptidase activity
0.45	GO:0006953	acute-phase response
0.42	GO:0008211	glucocorticoid metabolic process
0.40	GO:0034097	response to cytokine
0.39	GO:0043434	response to peptide hormone
0.36	GO:0046687	response to chromate
0.36	GO:0033986	response to methanol
0.36	GO:0034014	response to triglyceride
0.36	GO:0006487	protein N-linked glycosylation
0.36	GO:0010288	response to lead ion

0.57	GO:0004867	serine-type endopeptidase inhibitor activity
0.51	GO:0002020	protease binding
0.47	GO:0042802	identical protein binding
0.42	GO:0005496	steroid binding
0.33	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.46	GO:0005794	Golgi apparatus
0.46	GO:0005783	endoplasmic reticulum
0.37	GO:1903561	extracellular vesicle
0.35	GO:0031093	platelet alpha granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.34	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0031984	organelle subcompartment

0.33

GO:0008233

sp|P17490|INHA_RAT
Inhibin alpha chain
Search

INHA

0.95	Inhibin alpha subunit

0.75	GO:0010469	regulation of receptor activity
0.71	GO:0042541	hemoglobin biosynthetic process
0.59	GO:0042127	regulation of cell proliferation
0.57	GO:0051726	regulation of cell cycle
0.54	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.53	GO:0060395	SMAD protein signal transduction
0.53	GO:0030509	BMP signaling pathway
0.50	GO:0043408	regulation of MAPK cascade
0.49	GO:0048468	cell development
0.48	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.73	GO:0005179	hormone activity
0.53	GO:0005160	transforming growth factor beta receptor binding
0.51	GO:0005125	cytokine activity
0.44	GO:0034711	inhibin binding
0.40	GO:0046982	protein heterodimerization activity

0.70	GO:0043512	inhibin A complex
0.69	GO:0034673	inhibin-betaglycan-ActRII complex
0.45	GO:0043513	inhibin B complex
0.43	GO:0001917	photoreceptor inner segment
0.42	GO:0001750	photoreceptor outer segment
0.41	GO:0043025	neuronal cell body
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P17491|INHBB_RAT
Inhibin beta B chain
Search

INHBB

0.95	Inhibin beta B subunit

0.75	GO:0010469	regulation of receptor activity
0.62	GO:0032686	negative regulation of hepatocyte growth factor production
0.62	GO:0048176	regulation of hepatocyte growth factor biosynthetic process
0.62	GO:0046882	negative regulation of follicle-stimulating hormone secretion
0.61	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.60	GO:0060279	positive regulation of ovulation
0.59	GO:0042036	negative regulation of cytokine biosynthetic process
0.59	GO:0032924	activin receptor signaling pathway
0.58	GO:0046676	negative regulation of insulin secretion
0.56	GO:0045444	fat cell differentiation

0.78	GO:0008083	growth factor activity
0.77	GO:0005179	hormone activity
0.52	GO:0042803	protein homodimerization activity
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.36	GO:0034711	inhibin binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0046812	host cell surface binding
0.33	GO:0070699	type II activin receptor binding
0.33	GO:0003924	GTPase activity

0.66	GO:0005576	extracellular region
0.54	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0071944	cell periphery
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P17559|UTER_RAT
Uteroglobin
Search

SCGB1A1

0.93	Uteroglobin

0.75	GO:0034021	response to silicon dioxide
0.71	GO:0032696	negative regulation of interleukin-13 production
0.71	GO:0032714	negative regulation of interleukin-5 production
0.71	GO:0032713	negative regulation of interleukin-4 production
0.70	GO:0010193	response to ozone
0.68	GO:0032689	negative regulation of interferon-gamma production
0.67	GO:0042130	negative regulation of T cell proliferation
0.67	GO:0043086	negative regulation of catalytic activity
0.67	GO:0051384	response to glucocorticoid
0.65	GO:0043488	regulation of mRNA stability

0.84	GO:0019834	phospholipase A2 inhibitor activity
0.76	GO:0097160	polychlorinated biphenyl binding

0.64	GO:0005791	rough endoplasmic reticulum
0.63	GO:0030141	secretory granule
0.62	GO:0005576	extracellular region
0.60	GO:0005635	nuclear envelope

sp|P17625|GYS2_RAT
Glycogen [starch] synthase, liver
Search

GYS2

0.69	Glycogen [starch] synthase

0.76	GO:0005978	glycogen biosynthetic process
0.41	GO:0009743	response to carbohydrate
0.37	GO:0007507	heart development
0.36	GO:0045819	positive regulation of glycogen catabolic process
0.36	GO:0061723	glycophagy
0.36	GO:0090664	response to high population density
0.34	GO:0009267	cellular response to starvation
0.34	GO:0032868	response to insulin
0.34	GO:1901701	cellular response to oxygen-containing compound
0.34	GO:0071310	cellular response to organic substance

0.80	GO:0004373	glycogen (starch) synthase activity
0.38	GO:0019901	protein kinase binding
0.36	GO:0061547	glycogen synthase activity, transferring glucose-1-phosphate
0.35	GO:0005536	glucose binding
0.34	GO:0009011	starch synthase activity
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0008026	ATP-dependent helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.41	GO:0043265	ectoplasm
0.38	GO:0030864	cortical actin cytoskeleton
0.38	GO:0016234	inclusion body
0.36	GO:0005829	cytosol

0.80

EC:2.4.1.11

GO:0004373

sp|P17659|KCNA6_RAT
Potassium voltage-gated channel subfamily A member 6
Search

KCNA6

0.84	Potassium voltage-gated channel subfamily A member 6

0.77	GO:0051260	protein homooligomerization
0.76	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.41	GO:0086052	membrane repolarization during SA node cell action potential
0.41	GO:0086050	membrane repolarization during bundle of His cell action potential
0.41	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.41	GO:0060081	membrane hyperpolarization
0.40	GO:0086091	regulation of heart rate by cardiac conduction
0.39	GO:0043266	regulation of potassium ion transport
0.38	GO:0019229	regulation of vasoconstriction

0.78	GO:0005249	voltage-gated potassium channel activity
0.54	GO:0030955	potassium ion binding
0.40	GO:0051393	alpha-actinin binding
0.40	GO:0097110	scaffold protein binding
0.39	GO:0019870	potassium channel inhibitor activity
0.38	GO:0019901	protein kinase binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.78	GO:0008076	voltage-gated potassium channel complex
0.56	GO:0043679	axon terminus
0.55	GO:0030424	axon
0.40	GO:0014704	intercalated disc
0.39	GO:0045121	membrane raft
0.34	GO:0098889	intrinsic component of presynaptic membrane
0.34	GO:0098936	intrinsic component of postsynaptic membrane
0.34	GO:0099699	integral component of synaptic membrane
0.34	GO:0012505	endomembrane system
0.34	GO:0043198	dendritic shaft

0.33

EC:2.4

GO:0016757

sp|P17702|RL28_RAT
60S ribosomal protein L28
Search

RPL28

0.73	Ribosomal protein L28

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.44	GO:1903146	regulation of autophagy of mitochondrion
0.44	GO:1903955	positive regulation of protein targeting to mitochondrion
0.37	GO:0043009	chordate embryonic development
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0016787	hydrolase activity
0.33	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.43	GO:0030425	dendrite
0.43	GO:0044297	cell body
0.42	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.33	GO:0099512	supramolecular fiber
0.33	GO:0015630	microtubule cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

sp|P17708|DCAM_RAT
S-adenosylmethionine decarboxylase proenzyme
Search

AMD1

0.55	S-adenosylmethionine decarboxylase proenzyme

0.83	GO:0006597	spermine biosynthetic process
0.76	GO:0008295	spermidine biosynthetic process
0.68	GO:0006557	S-adenosylmethioninamine biosynthetic process
0.37	GO:0001701	in utero embryonic development
0.34	GO:0046500	S-adenosylmethionine metabolic process

0.80	GO:0004014	adenosylmethionine decarboxylase activity
0.49	GO:0019810	putrescine binding
0.33	GO:0005515	protein binding

0.43

GO:0005829

cytosol

0.80	EC:4.1.1.50	GO:0004014
0.80	KEGG:R00178	GO:0004014

sp|P17712|HXK4_RAT
Glucokinase
Search

GCK

0.58	Phosphotransferase

0.81	GO:0001678	cellular glucose homeostasis
0.73	GO:0046835	carbohydrate phosphorylation
0.70	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.57	GO:0034287	detection of monosaccharide stimulus
0.57	GO:0045725	positive regulation of glycogen biosynthetic process
0.57	GO:0050796	regulation of insulin secretion
0.56	GO:0090277	positive regulation of peptide hormone secretion

0.82	GO:0005536	glucose binding
0.79	GO:0004396	hexokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005509	calcium ion binding

0.49	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.43	GO:0005739	mitochondrion

0.79

EC:2.7.1.1

GO:0004396

sp|P17764|THIL_RAT
Acetyl-CoA acetyltransferase, mitochondrial
Search

ACAT1

0.40	Acetyl-CoA acetyltransferase

0.59	GO:1902860	propionyl-CoA biosynthetic process
0.57	GO:0006550	isoleucine catabolic process
0.56	GO:0046356	acetyl-CoA catabolic process
0.54	GO:0046952	ketone body catabolic process
0.50	GO:0006085	acetyl-CoA biosynthetic process
0.50	GO:0015937	coenzyme A biosynthetic process
0.46	GO:0006635	fatty acid beta-oxidation
0.41	GO:0072229	metanephric proximal convoluted tubule development
0.40	GO:0060612	adipose tissue development
0.39	GO:0001889	liver development

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.50	GO:0016885	ligase activity, forming carbon-carbon bonds
0.46	GO:0016830	carbon-carbon lyase activity
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0019899	enzyme binding
0.36	GO:0046872	metal ion binding
0.35	GO:0050662	coenzyme binding
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0015035	protein disulfide oxidoreductase activity
0.33	GO:0004222	metalloendopeptidase activity

0.45	GO:0005739	mitochondrion
0.44	GO:0019866	organelle inner membrane
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.34	GO:0005777	peroxisome
0.34	GO:0031012	extracellular matrix
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.64

GO:0016747

sp|P17777|LIF_RAT
Leukemia inhibitory factor
Search

LIF

0.94	LIF, interleukin 6 family cytokine

0.85	GO:1901676	positive regulation of histone H3-K27 acetylation
0.84	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
0.84	GO:0048861	leukemia inhibitory factor signaling pathway
0.83	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation
0.82	GO:0060708	spongiotrophoblast differentiation
0.82	GO:0060426	lung vasculature development
0.82	GO:0060463	lung lobe morphogenesis
0.82	GO:0007260	tyrosine phosphorylation of STAT protein
0.82	GO:0045651	positive regulation of macrophage differentiation
0.81	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein

0.87	GO:0005146	leukemia inhibitory factor receptor binding
0.81	GO:0005125	cytokine activity
0.72	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.63	GO:0005829	cytosol

sp|P17945|HGF_RAT
Hepatocyte growth factor
Search

HGF

0.94	Hepatocyte growth factor a

0.68	GO:0010469	regulation of receptor activity
0.68	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.65	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
0.64	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death
0.64	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.63	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.62	GO:1902947	regulation of tau-protein kinase activity
0.62	GO:0051450	myoblast proliferation
0.61	GO:0050918	positive chemotaxis
0.61	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.70	GO:0008083	growth factor activity
0.69	GO:0004252	serine-type endopeptidase activity
0.63	GO:0042056	chemoattractant activity
0.54	GO:0042802	identical protein binding
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity

0.48	GO:0005615	extracellular space
0.38	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

0.69	EC:3.4.21	GO:0004252
0.38	KEGG:R04545	GO:0046934

sp|P17955|NUP62_RAT
Nuclear pore glycoprotein p62
Search

NUP62

0.92	Nucleoporin 62 like

0.70	GO:0051169	nuclear transport
0.60	GO:0046601	positive regulation of centriole replication
0.59	GO:1904781	positive regulation of protein localization to centrosome
0.58	GO:0007100	mitotic centrosome separation
0.57	GO:1903438	positive regulation of mitotic cytokinetic process
0.56	GO:0007080	mitotic metaphase plate congression
0.56	GO:0098534	centriole assembly
0.56	GO:0045840	positive regulation of mitotic nuclear division
0.56	GO:0060236	regulation of mitotic spindle organization
0.55	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.80	GO:0017056	structural constituent of nuclear pore
0.58	GO:0046966	thyroid hormone receptor binding
0.57	GO:0042169	SH2 domain binding
0.57	GO:0030159	receptor signaling complex scaffold activity
0.55	GO:0051425	PTB domain binding
0.54	GO:0043130	ubiquitin binding
0.53	GO:0051879	Hsp90 protein binding
0.53	GO:0030544	Hsp70 protein binding
0.44	GO:0005543	phospholipid binding
0.34	GO:0019894	kinesin binding

0.78	GO:0005643	nuclear pore
0.58	GO:0090543	Flemming body
0.54	GO:0072686	mitotic spindle
0.53	GO:0031965	nuclear membrane
0.53	GO:0000922	spindle pole
0.53	GO:0005813	centrosome
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0005737	cytoplasm
0.35	GO:0005642	annulate lamellae

sp|P17977|CATG_RAT
Cathepsin G (Fragment)
Search

0.88	Cathepsin G (Fragment)

0.66	GO:0070946	neutrophil mediated killing of gram-positive bacterium
0.61	GO:0006508	proteolysis
0.60	GO:0044130	negative regulation of growth of symbiont in host
0.58	GO:0019731	antibacterial humoral response
0.58	GO:0050832	defense response to fungus
0.57	GO:0071222	cellular response to lipopolysaccharide
0.57	GO:0050829	defense response to Gram-negative bacterium
0.54	GO:0050778	positive regulation of immune response
0.47	GO:0006468	protein phosphorylation
0.42	GO:0008626	granzyme-mediated apoptotic signaling pathway

0.69	GO:0004252	serine-type endopeptidase activity
0.56	GO:0008201	heparin binding

0.59	GO:0030141	secretory granule
0.55	GO:0010494	cytoplasmic stress granule
0.52	GO:0031012	extracellular matrix
0.52	GO:0005615	extracellular space
0.43	GO:0005886	plasma membrane
0.39	GO:1903561	extracellular vesicle
0.38	GO:0005882	intermediate filament
0.36	GO:0005634	nucleus

0.69

GO:0004252

sp|P17982|NAR2A_RAT
T-cell ecto-ADP-ribosyltransferase 1
Search

0.74	T-cell ecto-ADP-ribosyltransferase 1

0.84	GO:0006471	protein ADP-ribosylation
0.46	GO:0019677	NAD catabolic process
0.41	GO:0018195	peptidyl-arginine modification
0.34	GO:0046677	response to antibiotic
0.33	GO:0006501	C-terminal protein lipidation

0.85	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.49	GO:0003953	NAD+ nucleosidase activity
0.43	GO:0003950	NAD+ ADP-ribosyltransferase activity

0.43	GO:0046658	anchored component of plasma membrane
0.42	GO:0031233	intrinsic component of external side of plasma membrane
0.39	GO:0005576	extracellular region
0.36	GO:0044194	cytolytic granule
0.36	GO:0019897	extrinsic component of plasma membrane
0.32	GO:0031982	vesicle
0.32	GO:0005887	integral component of plasma membrane

0.85

EC:2.4.2.31

GO:0003956

sp|P17988|ST1A1_RAT
Sulfotransferase 1A1
Search

0.56	Sulfotransferase

0.52	GO:0051923	sulfation
0.49	GO:0018958	phenol-containing compound metabolic process
0.47	GO:0006805	xenobiotic metabolic process
0.46	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.46	GO:0006068	ethanol catabolic process
0.45	GO:0042445	hormone metabolic process
0.42	GO:0008202	steroid metabolic process
0.42	GO:0006575	cellular modified amino acid metabolic process
0.41	GO:0009812	flavonoid metabolic process
0.37	GO:0000103	sulfate assimilation

0.78	GO:0008146	sulfotransferase activity
0.36	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.36	GO:0005515	protein binding
0.35	GO:0043199	sulfate binding

0.38

GO:0005829

cytosol

0.78

GO:0008146

sp|P18088|DCE1_RAT
Glutamate decarboxylase 1
Search

GAD1

0.52	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.57	GO:0035641	locomotory exploration behavior
0.56	GO:0035176	social behavior
0.46	GO:0042136	neurotransmitter biosynthetic process
0.39	GO:0016053	organic acid biosynthetic process
0.38	GO:0042493	response to drug
0.37	GO:1901566	organonitrogen compound biosynthetic process
0.36	GO:0018352	protein-pyridoxal-5-phosphate linkage
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.42	GO:0016595	glutamate binding
0.41	GO:0047485	protein N-terminus binding
0.39	GO:0046982	protein heterodimerization activity

0.57	GO:0060077	inhibitory synapse
0.55	GO:0043679	axon terminus
0.54	GO:0048786	presynaptic active zone
0.53	GO:0030424	axon
0.51	GO:0005938	cell cortex
0.44	GO:0005739	mitochondrion
0.36	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle
0.35	GO:0030665	clathrin-coated vesicle membrane
0.33	GO:0005886	plasma membrane

0.68

EC:4.1.1

GO:0016831

sp|P18090|ADRB1_RAT
Beta-1 adrenergic receptor
Search

0.87	Beta-1 adrenergic receptor

0.84	GO:0071875	adrenergic receptor signaling pathway
0.81	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.74	GO:0045823	positive regulation of heart contraction
0.68	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.65	GO:0001659	temperature homeostasis
0.64	GO:0043950	positive regulation of cAMP-mediated signaling
0.63	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine
0.63	GO:0030819	positive regulation of cAMP biosynthetic process
0.61	GO:0002024	diet induced thermogenesis
0.61	GO:0002027	regulation of heart rate

0.85	GO:0004939	beta-adrenergic receptor activity
0.64	GO:0051380	norepinephrine binding
0.61	GO:0031690	adrenergic receptor binding
0.59	GO:0051379	epinephrine binding
0.58	GO:0005057	signal transducer activity, downstream of receptor
0.57	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.54	GO:0030165	PDZ domain binding
0.51	GO:0046983	protein dimerization activity
0.46	GO:0042802	identical protein binding
0.39	GO:0050824	water binding

0.58	GO:0005769	early endosome
0.54	GO:0005886	plasma membrane
0.47	GO:0043235	receptor complex
0.37	GO:0098794	postsynapse
0.37	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P18113|THB_RAT
Thyroid hormone receptor beta
Search

THRB

0.94	Thyroid hormone receptor beta

0.80	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0008050	female courtship behavior
0.55	GO:0060509	Type I pneumocyte differentiation
0.55	GO:0007621	negative regulation of female receptivity
0.51	GO:0008016	regulation of heart contraction

0.85	GO:0004887	thyroid hormone receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.56	GO:0070324	thyroid hormone binding
0.52	GO:0031490	chromatin DNA binding
0.46	GO:0019899	enzyme binding
0.38	GO:0000989	transcription factor activity, transcription factor binding
0.36	GO:0003690	double-stranded DNA binding
0.34	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.45	GO:0031974	membrane-enclosed lumen
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P18125|CP7A1_RAT
Cholesterol 7-alpha-monooxygenase
Search

CYP7A1

0.97	Cholesterol 7-alpha-monooxygenase

0.86	GO:0006707	cholesterol catabolic process
0.86	GO:0006699	bile acid biosynthetic process
0.85	GO:0071333	cellular response to glucose stimulus
0.84	GO:0042632	cholesterol homeostasis
0.61	GO:0070857	regulation of bile acid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0071397	cellular response to cholesterol
0.36	GO:1904253	positive regulation of bile acid metabolic process
0.36	GO:0010893	positive regulation of steroid biosynthetic process
0.34	GO:0031328	positive regulation of cellular biosynthetic process

0.86	GO:0008123	cholesterol 7-alpha-monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity

0.66	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.33	GO:0005740	mitochondrial envelope
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:1.14.13.17

GO:0008123

sp|P18163|ACSL1_RAT
Long-chain-fatty-acid--CoA ligase 1
Search

ACSL1

0.60	Long-chain fatty acid CoA ligase

0.56	GO:0033211	adiponectin-activated signaling pathway
0.56	GO:0044539	long-chain fatty acid import
0.54	GO:0001676	long-chain fatty acid metabolic process
0.51	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.45	GO:0008610	lipid biosynthetic process
0.39	GO:0034201	response to oleic acid
0.38	GO:0007584	response to nutrient
0.38	GO:0006641	triglyceride metabolic process
0.37	GO:0007405	neuroblast proliferation
0.37	GO:0042178	xenobiotic catabolic process

0.55	GO:0004467	long-chain fatty acid-CoA ligase activity
0.44	GO:0102391	decanoate--CoA ligase activity
0.35	GO:0003987	acetate-CoA ligase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004197	cysteine-type endopeptidase activity

0.44	GO:0005739	mitochondrion
0.38	GO:0031903	microbody membrane
0.38	GO:0044439	peroxisomal part
0.38	GO:0031968	organelle outer membrane
0.37	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.55

EC:6.2.1.3

GO:0004467

sp|P18211|HB2D_RAT
Rano class II histocompatibility antigen, D-1 beta chain
Search

0.42	MHC class II histocompatibility antigen, DR beta chain

0.79	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.72	GO:0006955	immune response
0.41	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.37	GO:0002377	immunoglobulin production
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:2001179	regulation of interleukin-10 secretion
0.37	GO:0032673	regulation of interleukin-4 production
0.37	GO:0032689	negative regulation of interferon-gamma production
0.37	GO:0016045	detection of bacterium
0.37	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus

0.38	GO:0042605	peptide antigen binding
0.36	GO:0023026	MHC class II protein complex binding
0.35	GO:1990405	protein antigen binding
0.34	GO:0042609	CD4 receptor binding
0.34	GO:0015643	toxic substance binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0008134	transcription factor binding

0.74	GO:0042613	MHC class II protein complex
0.40	GO:0005770	late endosome
0.40	GO:0005765	lysosomal membrane
0.39	GO:0010008	endosome membrane
0.37	GO:0009897	external side of plasma membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0005769	early endosome
0.33	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|P18265|GSK3A_RAT
Glycogen synthase kinase-3 alpha
Search

GSK3A

0.83	LOW QUALITY PROTEIN: glycogen synthase kinase-3 alpha

0.63	GO:0006468	protein phosphorylation
0.57	GO:0036015	response to interleukin-3
0.57	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development
0.57	GO:2000467	positive regulation of glycogen (starch) synthase activity
0.56	GO:0106071	positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.56	GO:0044027	hypermethylation of CpG island
0.56	GO:0071879	positive regulation of adrenergic receptor signaling pathway
0.56	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.56	GO:0003007	heart morphogenesis
0.55	GO:0071285	cellular response to lithium ion

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0005102	receptor binding
0.46	GO:0050321	tau-protein kinase activity
0.44	GO:0034236	protein kinase A catalytic subunit binding
0.41	GO:0034452	dynactin binding
0.41	GO:0051059	NF-kappaB binding

0.43	GO:0005739	mitochondrion
0.43	GO:0030877	beta-catenin destruction complex
0.39	GO:0015630	microtubule cytoskeleton
0.39	GO:0044430	cytoskeletal part
0.38	GO:0005634	nucleus
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.36	GO:0005829	cytosol
0.36	GO:0098794	postsynapse
0.35	GO:0099512	supramolecular fiber

0.69

GO:0004674

sp|P18266|GSK3B_RAT
Glycogen synthase kinase-3 beta
Search

GSK3B

0.80	Glycogen synthase kinase-3 beta

0.63	GO:0006468	protein phosphorylation
0.58	GO:0071109	superior temporal gyrus development
0.57	GO:0051534	negative regulation of NFAT protein import into nucleus
0.57	GO:1904779	regulation of protein localization to centrosome
0.56	GO:0006983	ER overload response
0.54	GO:0001954	positive regulation of cell-matrix adhesion
0.54	GO:0046827	positive regulation of protein export from nucleus
0.54	GO:1901216	positive regulation of neuron death
0.54	GO:0001837	epithelial to mesenchymal transition
0.54	GO:0021766	hippocampus development

0.69	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0050321	tau-protein kinase activity
0.56	GO:0034452	dynactin binding
0.55	GO:0051059	NF-kappaB binding
0.55	GO:0034236	protein kinase A catalytic subunit binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0002039	p53 binding

0.55	GO:0030877	beta-catenin destruction complex
0.51	GO:0005813	centrosome
0.44	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.41	GO:1990909	Wnt signalosome
0.39	GO:0043198	dendritic shaft
0.39	GO:0030426	growth cone
0.39	GO:0014069	postsynaptic density
0.38	GO:0043025	neuronal cell body
0.38	GO:0048471	perinuclear region of cytoplasm

0.69

GO:0004674

sp|P18280|NTF3_RAT
Neurotrophin-3
Search

NTF3

0.62	Neurotrophin-3

0.75	GO:0010469	regulation of receptor activity
0.55	GO:0050930	induction of positive chemotaxis
0.55	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.55	GO:0032148	activation of protein kinase B activity
0.55	GO:0002092	positive regulation of receptor internalization
0.54	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.54	GO:0050918	positive chemotaxis
0.53	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.53	GO:0090630	activation of GTPase activity
0.53	GO:0000187	activation of MAPK activity

0.85	GO:0005165	neurotrophin receptor binding
0.78	GO:0008083	growth factor activity
0.55	GO:0042056	chemoattractant activity
0.35	GO:0048406	nerve growth factor binding

0.41	GO:0031410	cytoplasmic vesicle
0.40	GO:0005576	extracellular region
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P18291|GRAB_RAT
Granzyme B
Search

GZMB

0.94	Endogenous granzyme B

0.71	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.66	GO:0001909	leukocyte mediated cytotoxicity
0.66	GO:0002228	natural killer cell mediated immunity
0.61	GO:0006508	proteolysis
0.40	GO:0019835	cytolysis
0.39	GO:0002456	T cell mediated immunity
0.39	GO:0051873	killing by host of symbiont cells
0.39	GO:0044130	negative regulation of growth of symbiont in host
0.38	GO:0002446	neutrophil mediated immunity
0.38	GO:0022617	extracellular matrix disassembly

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0008201	heparin binding
0.36	GO:0005515	protein binding

0.66	GO:0030141	secretory granule
0.40	GO:0044194	cytolytic granule
0.38	GO:0031012	extracellular matrix
0.37	GO:0010494	cytoplasmic stress granule
0.36	GO:0005615	extracellular space
0.35	GO:0005769	early endosome
0.35	GO:0001772	immunological synapse
0.35	GO:0005829	cytosol
0.35	GO:0005766	primary lysosome
0.34	GO:0060205	cytoplasmic vesicle lumen

0.69

GO:0004252

sp|P18292|THRB_RAT
Prothrombin
Search

0.96	Prothrombin

0.82	GO:0007596	blood coagulation
0.81	GO:0006953	acute-phase response
0.61	GO:0006508	proteolysis
0.52	GO:0051838	cytolysis by host of symbiont cells
0.51	GO:0070945	neutrophil mediated killing of gram-negative bacterium
0.51	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
0.51	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.51	GO:0048712	negative regulation of astrocyte differentiation
0.50	GO:0042730	fibrinolysis
0.50	GO:0032967	positive regulation of collagen biosynthetic process

0.70	GO:0005509	calcium ion binding
0.69	GO:0004252	serine-type endopeptidase activity
0.51	GO:0070053	thrombospondin receptor activity
0.48	GO:0008201	heparin binding
0.48	GO:0001530	lipopolysaccharide binding
0.44	GO:0005102	receptor binding
0.39	GO:0070051	fibrinogen binding

0.66	GO:0005576	extracellular region
0.47	GO:0009897	external side of plasma membrane
0.30	GO:0031982	vesicle

0.69

GO:0004252

sp|P18297|SPRE_RAT
Sepiapterin reductase
Search

SPR

0.85	Sepiapterin reductase a

0.77	GO:0046146	tetrahydrobiopterin metabolic process
0.77	GO:0034312	diol biosynthetic process
0.69	GO:0042559	pteridine-containing compound biosynthetic process
0.62	GO:0009108	coenzyme biosynthetic process
0.56	GO:0006809	nitric oxide biosynthetic process
0.51	GO:0055114	oxidation-reduction process
0.40	GO:0019889	pteridine metabolic process
0.39	GO:0050882	voluntary musculoskeletal movement
0.39	GO:0042415	norepinephrine metabolic process
0.39	GO:0042428	serotonin metabolic process

0.85	GO:0004757	sepiapterin reductase activity
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0102306	benzil reductase [(S)-benzoin-forming] activity
0.36	GO:0004033	aldo-keto reductase (NADP) activity
0.34	GO:0050661	NADP binding
0.32	GO:0022857	transmembrane transporter activity

0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:1.1.1.153

GO:0004757

sp|P18298|METK2_RAT
S-adenosylmethionine synthase isoform type-2
Search

MAT2A

0.54	S-adenosylmethionine synthase

0.78	GO:0006556	S-adenosylmethionine biosynthetic process
0.72	GO:0006730	one-carbon metabolic process
0.55	GO:0034214	protein hexamerization
0.53	GO:0051291	protein heterooligomerization
0.52	GO:1990830	cellular response to leukemia inhibitory factor
0.42	GO:0055013	cardiac muscle cell development
0.41	GO:0009087	methionine catabolic process
0.40	GO:0072358	cardiovascular system development
0.40	GO:0051289	protein homotetramerization
0.35	GO:0051591	response to cAMP

0.79	GO:0004478	methionine adenosyltransferase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.50	GO:0042802	identical protein binding
0.34	GO:0008488	gamma-glutamyl carboxylase activity
0.34	GO:0016597	amino acid binding

0.59	GO:0048269	methionine adenosyltransferase complex
0.43	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:2.5.1.6

GO:0004478

sp|P18331|INHBA_RAT
Inhibin beta A chain
Search

INHBA

0.97	Inhibin beta A subunit

0.76	GO:0010469	regulation of receptor activity
0.65	GO:0042701	progesterone secretion
0.64	GO:0046880	regulation of follicle-stimulating hormone secretion
0.63	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.63	GO:0042541	hemoglobin biosynthetic process
0.62	GO:0060279	positive regulation of ovulation
0.62	GO:0032924	activin receptor signaling pathway
0.62	GO:0045648	positive regulation of erythrocyte differentiation
0.61	GO:0021773	striatal medium spiny neuron differentiation
0.61	GO:0061029	eyelid development in camera-type eye

0.78	GO:0008083	growth factor activity
0.73	GO:0005179	hormone activity
0.62	GO:0070699	type II activin receptor binding
0.58	GO:0017046	peptide hormone binding
0.58	GO:0005125	cytokine activity
0.52	GO:0042802	identical protein binding
0.48	GO:0005160	transforming growth factor beta receptor binding
0.43	GO:0034711	inhibin binding
0.39	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.54	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0043234	protein complex

sp|P18395|CSDE1_RAT
Cold shock domain-containing protein E1
Search

CSDE1

0.91	Cold shock domain-containing protein E1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0006401	RNA catabolic process
0.42	GO:0016071	mRNA metabolic process
0.41	GO:0010605	negative regulation of macromolecule metabolic process
0.33	GO:0008584	male gonad development
0.32	GO:0007165	signal transduction

0.55	GO:0003677	DNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0003723	RNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005515	protein binding

0.48	GO:0070937	CRD-mediated mRNA stability complex
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005829	cytosol
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P18418|CALR_RAT
Calreticulin
Search

CALR

0.77	Calreticulin like

0.69	GO:0006457	protein folding
0.59	GO:0002502	peptide antigen assembly with MHC class I protein complex
0.58	GO:1901164	negative regulation of trophoblast cell migration
0.58	GO:2000510	positive regulation of dendritic cell chemotaxis
0.58	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.57	GO:0090398	cellular senescence
0.56	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.56	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway
0.56	GO:0071157	negative regulation of cell cycle arrest
0.56	GO:0050766	positive regulation of phagocytosis

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.57	GO:0050681	androgen receptor binding
0.55	GO:0005178	integrin binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0003729	mRNA binding
0.49	GO:0030246	carbohydrate binding
0.39	GO:0042562	hormone binding
0.38	GO:0042277	peptide binding
0.36	GO:0001849	complement component C1q binding

0.70	GO:0005783	endoplasmic reticulum
0.54	GO:0005844	polysome
0.53	GO:0009897	external side of plasma membrane
0.53	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005635	nuclear envelope
0.50	GO:0005615	extracellular space
0.49	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.48	GO:0070013	intracellular organelle lumen
0.47	GO:0005829	cytosol
0.47	GO:0031984	organelle subcompartment

sp|P18420|PSA1_RAT
Proteasome subunit alpha type-1
Search

PSMA1

0.49	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.70	GO:0043632	modification-dependent macromolecule catabolic process
0.53	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
0.38	GO:0002376	immune system process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.77	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.50	GO:0001530	lipopolysaccharide binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.59	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.44	GO:0005813	centrosome
0.41	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.34	GO:0005844	polysome
0.30	GO:0016021	integral component of membrane

sp|P18421|PSB1_RAT
Proteasome subunit beta type-1
Search

PSMB1

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.76	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0044446	intracellular organelle part
0.33	GO:0012505	endomembrane system

sp|P18422|PSA3_RAT
Proteasome subunit alpha type-3
Search

PSMA3

0.49	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.71	GO:0043632	modification-dependent macromolecule catabolic process
0.50	GO:0052548	regulation of endopeptidase activity
0.36	GO:0007224	smoothened signaling pathway
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.60	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.38	GO:0045202	synapse
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|P18424|LCAT_RAT
Phosphatidylcholine-sterol acyltransferase
Search

LCAT

0.92	Phosphatidylcholine-sterol acyltransferase

0.79	GO:0034435	cholesterol esterification
0.79	GO:0090107	regulation of high-density lipoprotein particle assembly
0.76	GO:0034372	very-low-density lipoprotein particle remodeling
0.75	GO:0034375	high-density lipoprotein particle remodeling
0.74	GO:0043691	reverse cholesterol transport
0.72	GO:0008203	cholesterol metabolic process
0.71	GO:0046470	phosphatidylcholine metabolic process
0.71	GO:0042632	cholesterol homeostasis
0.64	GO:0042158	lipoprotein biosynthetic process
0.63	GO:0046474	glycerophospholipid biosynthetic process

0.79	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity
0.77	GO:0034186	apolipoprotein A-I binding
0.39	GO:0004623	phospholipase A2 activity

0.73	GO:0034364	high-density lipoprotein particle
0.42	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.79

EC:2.3.1.43

GO:0004607

sp|P18427|FSHB_RAT
Follitropin subunit beta
Search

FSHB

0.95	Follicle stimulating hormone beta subunit

0.76	GO:0010469	regulation of receptor activity
0.59	GO:0042699	follicle-stimulating hormone signaling pathway
0.58	GO:0060011	Sertoli cell proliferation
0.57	GO:0007179	transforming growth factor beta receptor signaling pathway
0.57	GO:0046852	positive regulation of bone remodeling
0.56	GO:0045124	regulation of bone resorption
0.55	GO:0045670	regulation of osteoclast differentiation
0.54	GO:0032846	positive regulation of homeostatic process
0.49	GO:0010628	positive regulation of gene expression
0.45	GO:0007267	cell-cell signaling

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.40	GO:0005737	cytoplasm
0.35	GO:0031982	vesicle
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P18437|HMGN2_RAT
Non-histone chromosomal protein HMG-17
Search

HMGN2

0.94	High mobility group nucleosome-binding domain-containing protein 4

0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0031640	killing of cells of other organism
0.36	GO:0040034	regulation of development, heterochronic
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0007283	spermatogenesis
0.33	GO:0006334	nucleosome assembly
0.33	GO:0006508	proteolysis

0.85	GO:0031492	nucleosomal DNA binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0004181	metallocarboxypeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0008270	zinc ion binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.36	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm

0.34

GO:0004181

sp|P18445|RL27A_RAT
60S ribosomal protein L27a
Search

RPL27A

0.82	Ribosomal protein L27a

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.62	GO:0003735	structural constituent of ribosome
0.41	GO:0003723	RNA binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.66	GO:0015934	large ribosomal subunit
0.48	GO:0022626	cytosolic ribosome
0.41	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|P18484|AP2A2_RAT
AP-2 complex subunit alpha-2
Search

AP2A2

0.69	AP-2 complex subunit alpha

0.71	GO:0072583	clathrin-dependent endocytosis
0.69	GO:0006886	intracellular protein transport
0.38	GO:0060218	hematopoietic stem cell differentiation
0.38	GO:0009950	dorsal/ventral axis specification
0.35	GO:0032802	low-density lipoprotein particle receptor catabolic process
0.35	GO:2000026	regulation of multicellular organismal development
0.35	GO:0034383	low-density lipoprotein particle clearance
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0043312	neutrophil degranulation
0.35	GO:2000736	regulation of stem cell differentiation

0.85	GO:0035615	clathrin adaptor activity
0.64	GO:0008565	protein transporter activity
0.52	GO:0097718	disordered domain specific binding
0.49	GO:0019901	protein kinase binding
0.37	GO:0008289	lipid binding
0.34	GO:0032403	protein complex binding
0.32	GO:0043168	anion binding

0.78	GO:0030131	clathrin adaptor complex
0.73	GO:0005905	clathrin-coated pit
0.47	GO:0031410	cytoplasmic vesicle
0.40	GO:0005794	Golgi apparatus
0.37	GO:0012506	vesicle membrane
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0098797	plasma membrane protein complex
0.34	GO:0098793	presynapse
0.34	GO:0005764	lysosome
0.34	GO:0044446	intracellular organelle part

sp|P18506|GBRD_RAT
Gamma-aminobutyric acid receptor subunit delta
Search

GABRD

0.97	Gamma-aminobutyric acid type A receptor delta subunit

0.60	GO:0007165	signal transduction
0.59	GO:0034220	ion transmembrane transport
0.39	GO:0007268	chemical synaptic transmission
0.38	GO:0006821	chloride transport
0.36	GO:0007601	visual perception

0.82	GO:0004890	GABA-A receptor activity
0.74	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0005254	chloride channel activity
0.34	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.48	GO:1902711	GABA-A receptor complex
0.39	GO:0034707	chloride channel complex
0.39	GO:0098794	postsynapse
0.38	GO:0030054	cell junction

sp|P18508|GBRG2_RAT
Gamma-aminobutyric acid receptor subunit gamma-2
Search

GABRG2

0.95	Gamma-aminobutyric acid receptor subunit epsilon

0.85	GO:0007214	gamma-aminobutyric acid signaling pathway
0.77	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0071420	cellular response to histamine
0.52	GO:0030534	adult behavior
0.50	GO:0009791	post-embryonic development
0.50	GO:0007268	chemical synaptic transmission

0.84	GO:0004890	GABA-A receptor activity
0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.50	GO:0005254	chloride channel activity
0.36	GO:0008503	benzodiazepine receptor activity
0.35	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.55	GO:1902711	GABA-A receptor complex
0.51	GO:0030424	axon
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.39	GO:0030425	dendrite
0.39	GO:0030054	cell junction
0.39	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0060077	inhibitory synapse
0.36	GO:0031252	cell leading edge

sp|P18576|NFYA_RAT
Nuclear transcription factor Y subunit alpha
Search

NFYA

0.93	Nuclear transcription factor Y subunit alpha

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.38	GO:0048511	rhythmic process
0.37	GO:0051254	positive regulation of RNA metabolic process
0.37	GO:0010557	positive regulation of macromolecule biosynthetic process
0.37	GO:0031328	positive regulation of cellular biosynthetic process
0.37	GO:2000036	regulation of stem cell population maintenance
0.37	GO:2000648	positive regulation of stem cell proliferation
0.37	GO:0006366	transcription by RNA polymerase II

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.39	GO:0001046	core promoter sequence-specific DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0001221	transcription cofactor binding

0.81	GO:0016602	CCAAT-binding factor complex
0.48	GO:0032993	protein-DNA complex
0.47	GO:0005654	nucleoplasm

sp|P18588|MX1_RAT
Interferon-induced GTP-binding protein Mx1
Search

MX1

0.82	Myxovirus resistance protein 2

0.41	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.40	GO:0051607	defense response to virus
0.40	GO:0035455	response to interferon-alpha
0.40	GO:0000266	mitochondrial fission
0.39	GO:0046822	regulation of nucleocytoplasmic transport
0.39	GO:0045087	innate immune response
0.38	GO:0051726	regulation of cell cycle
0.37	GO:0061025	membrane fusion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008017	microtubule binding

0.38	GO:0005643	nuclear pore
0.36	GO:0031966	mitochondrial membrane

sp|P18589|MX2_RAT
Interferon-induced GTP-binding protein Mx2
Search

MX1

0.82	Myxovirus resistance protein 2

0.42	GO:0035455	response to interferon-alpha
0.41	GO:0051607	defense response to virus
0.40	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.40	GO:0046822	regulation of nucleocytoplasmic transport
0.39	GO:0000266	mitochondrial fission
0.38	GO:0051726	regulation of cell cycle
0.38	GO:0045087	innate immune response
0.37	GO:0061025	membrane fusion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008017	microtubule binding

0.39	GO:0005643	nuclear pore
0.36	GO:0031966	mitochondrial membrane

sp|P18590|MX3_RAT
Interferon-induced GTP-binding protein Mx3
Search

MX1

0.82	Myxovirus resistance protein 2

0.42	GO:0035455	response to interferon-alpha
0.41	GO:0051607	defense response to virus
0.40	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.40	GO:0046822	regulation of nucleocytoplasmic transport
0.39	GO:0000266	mitochondrial fission
0.38	GO:0051726	regulation of cell cycle
0.38	GO:0045087	innate immune response
0.37	GO:0061025	membrane fusion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008017	microtubule binding

0.39	GO:0005643	nuclear pore
0.36	GO:0031966	mitochondrial membrane

sp|P18596|AT2A3_RAT
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
Search

ATP2A3

0.58	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:1903779	regulation of cardiac conduction
0.33	GO:0006260	DNA replication

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.76	GO:0033017	sarcoplasmic reticulum membrane
0.35	GO:0031095	platelet dense tubular network membrane
0.34	GO:0031965	nuclear membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.6.3.8

GO:0005388

sp|P18598|ATP4B_RAT
Potassium-transporting ATPase subunit beta
Search

ATP4B

0.80	Potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.41	GO:0032496	response to lipopolysaccharide
0.40	GO:0007155	cell adhesion
0.40	GO:0048923	posterior lateral line neuromast hair cell differentiation
0.40	GO:0010243	response to organonitrogen compound
0.39	GO:0048840	otolith development
0.39	GO:0001964	startle response
0.39	GO:0033577	protein glycosylation in endoplasmic reticulum
0.38	GO:0042472	inner ear morphogenesis

0.42	GO:0008900	potassium:proton exchanging ATPase activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0051117	ATPase binding
0.33	GO:0005391	sodium:potassium-exchanging ATPase activity
0.33	GO:0001671	ATPase activator activity

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.36	GO:0005783	endoplasmic reticulum

0.42

EC:3.6.3.10

GO:0008900

sp|P18614|ITA1_RAT
Integrin alpha-1
Search

ITGA1

0.97	Laminin and collagen receptor

0.79	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.60	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.59	GO:0045123	cellular extravasation
0.59	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.58	GO:0030593	neutrophil chemotaxis
0.55	GO:0008285	negative regulation of cell proliferation
0.40	GO:0043525	positive regulation of neuron apoptotic process
0.40	GO:0042311	vasodilation
0.40	GO:0000187	activation of MAPK activity

0.62	GO:0098639	collagen binding involved in cell-matrix adhesion
0.57	GO:0019903	protein phosphatase binding
0.38	GO:0038064	collagen receptor activity
0.38	GO:0005102	receptor binding
0.35	GO:0046872	metal ion binding
0.34	GO:0001540	amyloid-beta binding
0.32	GO:0008168	methyltransferase activity
0.31	GO:0003676	nucleic acid binding

0.81	GO:0008305	integrin complex
0.58	GO:0045178	basal part of cell
0.57	GO:0005925	focal adhesion
0.56	GO:0009897	external side of plasma membrane
0.40	GO:0043204	perikaryon
0.40	GO:0001669	acrosomal vesicle
0.39	GO:0045121	membrane raft
0.39	GO:0043005	neuron projection
0.38	GO:0070062	extracellular exosome
0.35	GO:0005581	collagen trimer

0.32

GO:0008168

sp|P18645|GALE_RAT
UDP-glucose 4-epimerase
Search

GALE

0.40	UDP-galactose-4-epimerase

0.76	GO:0006012	galactose metabolic process
0.51	GO:0019320	hexose catabolic process
0.36	GO:0061622	glycolytic process through glucose-1-phosphate
0.34	GO:0042125	protein galactosylation

0.78	GO:0003978	UDP-glucose 4-epimerase activity
0.50	GO:0042803	protein homodimerization activity
0.42	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity
0.37	GO:0004419	hydroxymethylglutaryl-CoA lyase activity
0.37	GO:0050662	coenzyme binding
0.33	GO:0030246	carbohydrate binding

0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.78	EC:5.1.3.2	GO:0003978
0.37	KEGG:R01360	GO:0004419

sp|P18665|RM03_RAT
39S ribosomal protein L3, mitochondrial
Search

MRPL3

0.96	Mitochondrial ribosomal protein L3

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.52	GO:0005759	mitochondrial matrix
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P18666|ML12B_RAT
Myosin regulatory light chain 12B
Search

MYL12B

0.89	Myosin regulatory light chain

0.48	GO:0008360	regulation of cell shape
0.45	GO:0072659	protein localization to plasma membrane
0.36	GO:0070527	platelet aggregation
0.36	GO:0006936	muscle contraction
0.34	GO:0048013	ephrin receptor signaling pathway
0.34	GO:0031032	actomyosin structure organization

0.68	GO:0005509	calcium ion binding
0.53	GO:0032036	myosin heavy chain binding
0.46	GO:0035254	glutamate receptor binding
0.35	GO:0030898	actin-dependent ATPase activity
0.34	GO:0051015	actin filament binding
0.34	GO:0051020	GTPase binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0016460	myosin II complex
0.56	GO:0097517	contractile actin filament bundle
0.56	GO:0042641	actomyosin
0.55	GO:0030018	Z disc
0.50	GO:0005903	brush border
0.50	GO:0099738	cell cortex region
0.49	GO:0045177	apical part of cell
0.37	GO:0070062	extracellular exosome
0.35	GO:0097513	myosin II filament
0.34	GO:0005829	cytosol

sp|P18757|CGL_RAT
Cystathionine gamma-lyase
Search

CTH

0.82	Cystathionase (Cystathionine gamma-lyase)

0.51	GO:0019346	transsulfuration
0.49	GO:0019343	cysteine biosynthetic process via cystathionine
0.47	GO:0071266	'de novo' L-methionine biosynthetic process
0.42	GO:1904831	positive regulation of aortic smooth muscle cell differentiation
0.42	GO:0044524	protein sulfhydration
0.42	GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine
0.40	GO:0051289	protein homotetramerization
0.40	GO:1990823	response to leukemia inhibitory factor
0.40	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.40	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.67	GO:0070279	vitamin B6 binding
0.60	GO:0050662	coenzyme binding
0.53	GO:0043168	anion binding
0.52	GO:0016829	lyase activity
0.49	GO:0003962	cystathionine gamma-synthase activity
0.38	GO:0042802	identical protein binding

0.37

GO:0005737

cytoplasm

0.52

EC:4

GO:0016829

sp|P18863|HXB8_RAT
Homeobox protein Hox-B8 (Fragment)
Search

0.73	Homeobox transcription factor (Fragment)

0.66	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0007625	grooming behavior
0.51	GO:0019233	sensory perception of pain
0.51	GO:0045638	negative regulation of myeloid cell differentiation
0.50	GO:0008344	adult locomotory behavior
0.50	GO:0009653	anatomical structure morphogenesis
0.50	GO:1902679	negative regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.39	GO:0015630	microtubule cytoskeleton

sp|P18864|HXB7_RAT
Homeobox protein Hox-B7
Search

HOXB7

0.97	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

0.65	GO:0007275	multicellular organism development
0.60	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0002376	immune system process
0.54	GO:0009653	anatomical structure morphogenesis
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.51	GO:0030154	cell differentiation

0.62	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.59	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

sp|P18865|HXC4_RAT
Homeobox protein Hox-C4 (Fragment)
Search

0.67	Deformed protein (Fragment)

0.65	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0006366	transcription by RNA polymerase II
0.50	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process
0.50	GO:0009653	anatomical structure morphogenesis
0.49	GO:0048863	stem cell differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.48	GO:0071837	HMG box domain binding
0.47	GO:0035326	enhancer binding

0.61	GO:0005634	nucleus
0.45	GO:0030054	cell junction
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.36	GO:0015630	microtubule cytoskeleton

sp|P18866|HXC8_RAT
Homeobox protein Hox-C8 (Fragment)
Search

0.84	Homeobox protein Hox-C8

0.65	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0009653	anatomical structure morphogenesis
0.50	GO:1902679	negative regulation of RNA biosynthetic process
0.48	GO:0007625	grooming behavior
0.47	GO:0019233	sensory perception of pain
0.47	GO:0045638	negative regulation of myeloid cell differentiation
0.46	GO:0008344	adult locomotory behavior

0.65	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.46	GO:0015630	microtubule cytoskeleton
0.44	GO:0044446	intracellular organelle part

sp|P18867|HXD3_RAT
Homeobox protein Hox-D3 (Fragment)
Search

HOXD3

0.94	Homeobox protein Hox-D3 (Fragment)

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0061448	connective tissue development
0.50	GO:0009653	anatomical structure morphogenesis
0.49	GO:0007219	Notch signaling pathway
0.49	GO:0007160	cell-matrix adhesion
0.49	GO:0048522	positive regulation of cellular process
0.48	GO:0051962	positive regulation of nervous system development

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0071837	HMG box domain binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0016235	aggresome
0.47	GO:0043233	organelle lumen
0.43	GO:0044446	intracellular organelle part

sp|P18886|CPT2_RAT
Carnitine O-palmitoyltransferase 2, mitochondrial
Search

CPT2

0.89	Mitochondrial carnitine palmitoyltransferase II

0.40	GO:0006635	fatty acid beta-oxidation
0.37	GO:0015909	long-chain fatty acid transport
0.36	GO:1902001	fatty acid transmembrane transport
0.35	GO:0032365	intracellular lipid transport
0.35	GO:1990542	mitochondrial transmembrane transport
0.35	GO:0019216	regulation of lipid metabolic process

0.62

GO:0016746

transferase activity, transferring acyl groups

0.53	GO:0005730	nucleolus
0.51	GO:0005654	nucleoplasm
0.48	GO:0005739	mitochondrion
0.38	GO:0019866	organelle inner membrane

0.62

EC:2.3

GO:0016746

sp|P18889|PORF1_RAT
Putative preoptic regulatory factor 1
Search

0.37	Putative preoptic regulatory factor 1

0.75

GO:0010469

regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P18890|RHG39_RAT
Rho GTPase-activating protein 39 (Fragment)
Search

ARHGAP39

0.58	Rho GTPase-activating protein 39 (Fragment)

0.61	GO:0007165	signal transduction
0.34	GO:0051056	regulation of small GTPase mediated signal transduction
0.34	GO:0043547	positive regulation of GTPase activity

0.34

GO:0005096

GTPase activator activity

0.68	GO:0005856	cytoskeleton
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol

sp|P18897|SMR2_RAT
SMR2 protein
Search

0.69	Glutamine/glutamic acid-rich protein B

sp|P18901|DRD1_RAT
D(1A) dopamine receptor
Search

DRD1

0.97	Dopamine receptor D1

0.84	GO:0007212	dopamine receptor signaling pathway
0.84	GO:0042311	vasodilation
0.82	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.60	GO:1903351	cellular response to dopamine
0.59	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.59	GO:0007190	activation of adenylate cyclase activity
0.59	GO:0046960	sensitization
0.58	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.58	GO:0035106	operant conditioning
0.58	GO:0001661	conditioned taste aversion

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.60	GO:0035240	dopamine binding
0.36	GO:0031750	D3 dopamine receptor binding
0.36	GO:0031701	angiotensin receptor binding
0.35	GO:0001965	G-protein alpha-subunit binding
0.35	GO:0051117	ATPase binding
0.35	GO:0019903	protein phosphatase binding
0.34	GO:0032403	protein complex binding
0.34	GO:0046982	protein heterodimerization activity

0.66	GO:0005887	integral component of plasma membrane
0.58	GO:0060170	ciliary membrane
0.57	GO:0097730	non-motile cilium
0.48	GO:0005783	endoplasmic reticulum
0.43	GO:0005634	nucleus
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.38	GO:0031526	brush border membrane
0.36	GO:0044326	dendritic spine neck
0.36	GO:0044327	dendritic spine head

sp|P18910|ANPRA_RAT
Atrial natriuretic peptide receptor 1
Search

NPR1

0.57	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0007168	receptor guanylyl cyclase signaling pathway
0.48	GO:1900194	negative regulation of oocyte maturation
0.48	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.47	GO:0048513	animal organ development
0.46	GO:0051447	negative regulation of meiotic cell cycle
0.45	GO:0014855	striated muscle cell proliferation
0.45	GO:0001501	skeletal system development

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.63	GO:0016941	natriuretic peptide receptor activity
0.58	GO:0017046	peptide hormone binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0004016	adenylate cyclase activity
0.43	GO:0042802	identical protein binding
0.37	GO:0019901	protein kinase binding

0.48	GO:0043235	receptor complex
0.47	GO:0008074	guanylate cyclase complex, soluble
0.41	GO:0005887	integral component of plasma membrane

0.82

GO:0004383

sp|P18916|ACHG_RAT
Acetylcholine receptor subunit gamma
Search

CHRNG

0.95	Acetylcholine receptor subunit gamma

0.78	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.52	GO:0007271	synaptic transmission, cholinergic
0.51	GO:0035094	response to nicotine
0.51	GO:0007274	neuromuscular synaptic transmission
0.43	GO:0006936	muscle contraction
0.40	GO:0050881	musculoskeletal movement
0.40	GO:0006812	cation transport

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.52	GO:0042166	acetylcholine binding
0.37	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.52	GO:0005892	acetylcholine-gated channel complex

sp|P19020|DRD3_RAT
D(3) dopamine receptor
Search

DRD3

0.90	Dopamine receptor 3

0.84	GO:0007212	dopamine receptor signaling pathway
0.80	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.65	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.65	GO:0048148	behavioral response to cocaine
0.64	GO:0014059	regulation of dopamine secretion
0.64	GO:0060134	prepulse inhibition
0.64	GO:0034776	response to histamine
0.63	GO:0043278	response to morphine
0.63	GO:0001975	response to amphetamine
0.62	GO:0045776	negative regulation of blood pressure

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.54	GO:0035240	dopamine binding
0.43	GO:0042802	identical protein binding
0.43	GO:0004935	adrenergic receptor activity
0.43	GO:0031748	D1 dopamine receptor binding
0.40	GO:0019904	protein domain specific binding
0.37	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0015459	potassium channel regulator activity

0.66	GO:0005887	integral component of plasma membrane
0.47	GO:0060170	ciliary membrane
0.46	GO:0097458	neuron part
0.46	GO:0097730	non-motile cilium
0.44	GO:0099501	exocytic vesicle membrane
0.42	GO:0030139	endocytic vesicle
0.42	GO:0044456	synapse part
0.40	GO:0045177	apical part of cell
0.37	GO:0016328	lateral plasma membrane
0.36	GO:0036126	sperm flagellum

sp|P19024|KCNA5_RAT
Potassium voltage-gated channel subfamily A member 5
Search

KCNA5

0.90	Delayed rectifier K+ channel

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071804	cellular potassium ion transport
0.62	GO:0098662	inorganic cation transmembrane transport
0.60	GO:0086052	membrane repolarization during SA node cell action potential
0.60	GO:0086050	membrane repolarization during bundle of His cell action potential
0.59	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.58	GO:0060081	membrane hyperpolarization
0.56	GO:0086091	regulation of heart rate by cardiac conduction
0.54	GO:0043266	regulation of potassium ion transport

0.78	GO:0005249	voltage-gated potassium channel activity
0.56	GO:0051393	alpha-actinin binding
0.56	GO:0097110	scaffold protein binding
0.56	GO:0019870	potassium channel inhibitor activity
0.53	GO:0030955	potassium ion binding
0.52	GO:0019901	protein kinase binding
0.37	GO:0005102	receptor binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.55	GO:0014704	intercalated disc
0.53	GO:0045121	membrane raft
0.41	GO:0046691	intracellular canaliculus
0.39	GO:0030424	axon
0.39	GO:0030018	Z disc
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0005794	Golgi apparatus
0.36	GO:0098793	presynapse

sp|P19103|PPR1A_RAT
Protein phosphatase 1 regulatory subunit 1A
Search

PPP1R1A

0.97	Phosphatase 1, regulatory (Inhibitor) subunit 1B

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.48	GO:0006469	negative regulation of protein kinase activity
0.41	GO:0005977	glycogen metabolic process
0.35	GO:0006470	protein dephosphorylation

0.83	GO:0004864	protein phosphatase inhibitor activity
0.35	GO:0005515	protein binding
0.35	GO:0004721	phosphoprotein phosphatase activity

0.39	GO:0005615	extracellular space
0.37	GO:0005737	cytoplasm
0.35	GO:0099512	supramolecular fiber
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

GO:0004721

sp|P19112|F16P1_RAT
Fructose-1,6-bisphosphatase 1
Search

FBP1

0.52	Acipenser baerii fructose 1,6-bisphosphatase mRNA

0.68	GO:0016311	dephosphorylation
0.60	GO:0005975	carbohydrate metabolic process
0.58	GO:0071286	cellular response to magnesium ion
0.57	GO:0045820	negative regulation of glycolytic process
0.55	GO:0006002	fructose 6-phosphate metabolic process
0.54	GO:0051289	protein homotetramerization
0.54	GO:0006111	regulation of gluconeogenesis
0.54	GO:0046580	negative regulation of Ras protein signal transduction
0.54	GO:0030308	negative regulation of cell growth
0.52	GO:0035690	cellular response to drug

0.79	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity
0.54	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.53	GO:0042802	identical protein binding
0.52	GO:0016208	AMP binding
0.42	GO:0048029	monosaccharide binding
0.41	GO:0046872	metal ion binding

0.46	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0030018	Z disc
0.36	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.79

EC:3.1.3.11

GO:0042132

sp|P19132|FRIH_RAT
Ferritin heavy chain
Search

FTH1

0.54	Ferritin heavy chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.50	GO:0051238	sequestering of metal ion
0.47	GO:0051651	maintenance of location in cell
0.44	GO:0008285	negative regulation of cell proliferation
0.42	GO:0006955	immune response
0.40	GO:0048145	regulation of fibroblast proliferation
0.38	GO:0055114	oxidation-reduction process
0.35	GO:0060547	negative regulation of necrotic cell death
0.35	GO:0002446	neutrophil mediated immunity

0.76	GO:0008199	ferric iron binding
0.46	GO:0004322	ferroxidase activity
0.35	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding

0.40	GO:0044754	autolysosome
0.36	GO:0005739	mitochondrion
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0070288	ferritin complex
0.35	GO:0005615	extracellular space
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol

0.46

EC:1.16.3.1

GO:0004322

sp|P19139|CSK21_RAT
Casein kinase II subunit alpha
Search

CSNK2A1

0.78	Casein kinase II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.44	GO:0030307	positive regulation of cell growth
0.43	GO:0045732	positive regulation of protein catabolic process
0.43	GO:0008284	positive regulation of cell proliferation
0.42	GO:0051336	regulation of hydrolase activity
0.42	GO:0032268	regulation of cellular protein metabolic process
0.42	GO:0030177	positive regulation of Wnt signaling pathway
0.42	GO:0035303	regulation of dephosphorylation
0.41	GO:1905818	regulation of chromosome separation
0.40	GO:0043066	negative regulation of apoptotic process

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008013	beta-catenin binding
0.42	GO:0019888	protein phosphatase regulator activity
0.41	GO:0047485	protein N-terminus binding
0.38	GO:0042802	identical protein binding
0.36	GO:0043021	ribonucleoprotein complex binding

0.42	GO:0031519	PcG protein complex
0.41	GO:0016580	Sin3 complex
0.41	GO:0090545	CHD-type complex
0.40	GO:0090568	nuclear transcriptional repressor complex
0.40	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.68

GO:0004674

sp|P19218|GP2_RAT
Pancreatic secretory granule membrane major glycoprotein GP2
Search

GP2

0.93	Pancreatic zymogen granule membrane protein GP-2

0.55	GO:0072233	metanephric thick ascending limb development
0.54	GO:0072221	metanephric distal convoluted tubule development
0.54	GO:0072021	ascending thin limb development
0.54	GO:0072236	metanephric loop of Henle development
0.52	GO:0007588	excretion
0.52	GO:0007159	leukocyte cell-cell adhesion
0.51	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.51	GO:1990266	neutrophil migration
0.50	GO:2000021	regulation of ion homeostasis
0.46	GO:0048878	chemical homeostasis

0.54	GO:0005509	calcium ion binding
0.54	GO:0019864	IgG binding
0.40	GO:0003823	antigen binding
0.37	GO:0051537	2 iron, 2 sulfur cluster binding

0.64	GO:0005576	extracellular region
0.53	GO:0031225	anchored component of membrane
0.52	GO:0016324	apical plasma membrane
0.51	GO:0016323	basolateral plasma membrane
0.50	GO:0000922	spindle pole
0.48	GO:0005929	cilium
0.40	GO:0031253	cell projection membrane
0.38	GO:0031982	vesicle
0.38	GO:0098588	bounding membrane of organelle
0.35	GO:0045121	membrane raft

sp|P19222|CBPA2_RAT
Carboxypeptidase A2
Search

CPA2

0.82	Carboxypeptidase A2 isoform A

0.61	GO:0006508	proteolysis
0.35	GO:0007039	protein catabolic process in the vacuole
0.34	GO:0016573	histone acetylation

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding

0.50	GO:0005576	extracellular region
0.34	GO:0005773	vacuole
0.30	GO:0016020	membrane

0.78

GO:0004181

sp|P19223|CBPB1_RAT
Carboxypeptidase B
Search

CPB1

0.80	Pancreatic carboxypeptidase B

0.59	GO:0006508	proteolysis
0.50	GO:0002002	regulation of angiotensin levels in blood
0.35	GO:0071466	cellular response to xenobiotic stimulus

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding

0.50	GO:0044421	extracellular region part
0.37	GO:0046658	anchored component of plasma membrane
0.35	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

0.76

GO:0004181

sp|P19225|CP270_RAT
Cytochrome P450 2C70
Search

0.96	Cytochrome P450 family 2 subfamily C member 8

0.59	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0043651	linoleic acid metabolic process
0.41	GO:0042738	exogenous drug catabolic process
0.40	GO:0002933	lipid hydroxylation
0.39	GO:0070988	demethylation
0.38	GO:0008202	steroid metabolic process
0.36	GO:0006805	xenobiotic metabolic process
0.36	GO:0002244	hematopoietic progenitor cell differentiation
0.35	GO:0016098	monoterpenoid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0034875	caffeine oxidase activity
0.40	GO:0019825	oxygen binding
0.33	GO:0005515	protein binding

0.46	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P19234|NDUV2_RAT
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
Search

NDUFV2

0.86	NADH:ubiquinone oxidoreductase core subunit V2

0.75	GO:0048738	cardiac muscle tissue development
0.69	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.67	GO:0007399	nervous system development

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.64	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.54	GO:0046872	metal ion binding

0.75	GO:0005747	mitochondrial respiratory chain complex I
0.58	GO:0045272	plasma membrane respiratory chain complex I
0.56	GO:0043209	myelin sheath

0.64

EC:1.6.5.3

GO:0008137

sp|P19313|CYTS_RAT
Cystatin-S
Search

0.59	Cystatin-S

0.76	GO:0010951	negative regulation of endopeptidase activity
0.67	GO:2000116	regulation of cysteine-type endopeptidase activity
0.61	GO:0046687	response to chromate
0.57	GO:0001562	response to protozoan
0.56	GO:0048678	response to axon injury
0.55	GO:0007431	salivary gland development
0.53	GO:0008285	negative regulation of cell proliferation
0.52	GO:0001906	cell killing
0.51	GO:0014070	response to organic cyclic compound
0.51	GO:0009725	response to hormone

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.68	GO:0002020	protease binding

0.60	GO:0005615	extracellular space
0.53	GO:0030141	secretory granule

sp|P19327|5HT1A_RAT
5-hydroxytryptamine receptor 1A
Search

HTR1A

0.93	5-hydroxytryptamine receptor

0.84	GO:0042310	vasoconstriction
0.84	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.83	GO:0050795	regulation of behavior
0.81	GO:0046883	regulation of hormone secretion
0.78	GO:0008283	cell proliferation
0.63	GO:0014062	regulation of serotonin secretion
0.62	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.62	GO:0042053	regulation of dopamine metabolic process
0.61	GO:0042428	serotonin metabolic process
0.61	GO:0035640	exploration behavior

0.84	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.63	GO:0090722	receptor-receptor interaction
0.51	GO:0051378	serotonin binding
0.36	GO:0001965	G-protein alpha-subunit binding
0.33	GO:0008144	drug binding

0.66	GO:0005887	integral component of plasma membrane
0.36	GO:0043203	axon hillock
0.31	GO:0005622	intracellular

sp|P19328|ADA2B_RAT
Alpha-2B adrenergic receptor
Search

ADRA2B

0.84	LOW QUALITY PROTEIN: alpha-2B adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.85	GO:0006940	regulation of smooth muscle contraction
0.85	GO:0019229	regulation of vasoconstriction
0.85	GO:0030168	platelet activation
0.51	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.50	GO:0032148	activation of protein kinase B activity
0.47	GO:0045666	positive regulation of neuron differentiation
0.47	GO:0043410	positive regulation of MAPK cascade
0.42	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.40	GO:0007267	cell-cell signaling

0.86	GO:0004938	alpha2-adrenergic receptor activity
0.51	GO:0051379	epinephrine binding
0.34	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.51	GO:0005886	plasma membrane
0.34	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.33

GO:0004222

sp|P19332|TAU_RAT
Microtubule-associated protein tau
Search

MAPT

0.74	Microtubule-associated protein tau

0.79	GO:0045773	positive regulation of axon extension
0.79	GO:0031116	positive regulation of microtubule polymerization
0.71	GO:0000226	microtubule cytoskeleton organization
0.68	GO:0090258	negative regulation of mitochondrial fission
0.67	GO:1902474	positive regulation of protein localization to synapse
0.67	GO:0010917	negative regulation of mitochondrial membrane potential
0.67	GO:1903748	negative regulation of establishment of protein localization to mitochondrion
0.66	GO:1990000	amyloid fibril formation
0.66	GO:0032930	positive regulation of superoxide anion generation
0.65	GO:0047497	mitochondrion transport along microtubule

0.74	GO:0008017	microtubule binding
0.66	GO:0034185	apolipoprotein binding
0.65	GO:0071813	lipoprotein particle binding
0.59	GO:0017124	SH3 domain binding
0.59	GO:0051879	Hsp90 protein binding
0.59	GO:0051721	protein phosphatase 2A binding
0.57	GO:0048018	receptor ligand activity
0.57	GO:0042803	protein homodimerization activity
0.54	GO:0019901	protein kinase binding
0.53	GO:0099077	histone-dependent DNA binding

0.83	GO:0045298	tubulin complex
0.79	GO:0030424	axon
0.77	GO:0030426	growth cone
0.72	GO:0005874	microtubule
0.67	GO:0005829	cytosol
0.67	GO:0097418	neurofibrillary tangle
0.63	GO:0032589	neuron projection membrane
0.63	GO:0005875	microtubule associated complex
0.60	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.60	GO:0034399	nuclear periphery

sp|P19335|MYF6_RAT
Myogenic factor 6
Search

MYF6

0.86	Myogenic regulatory factor 4

0.81	GO:0007517	muscle organ development
0.61	GO:0014706	striated muscle tissue development
0.57	GO:0001756	somitogenesis
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006366	transcription by RNA polymerase II
0.56	GO:0048743	positive regulation of skeletal muscle fiber development
0.55	GO:1902680	positive regulation of RNA biosynthetic process
0.54	GO:1901739	regulation of myoblast fusion

0.68	GO:0046983	protein dimerization activity
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.50	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0003682	chromatin binding
0.33	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005667	transcription factor complex
0.35	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

0.33

GO:0004725

sp|P19356|HEM3_RAT
Porphobilinogen deaminase
Search

HMBS

0.45	Hydroxymethylbilane synthase a

0.79	GO:0018160	peptidyl-pyrromethane cofactor linkage
0.69	GO:0033014	tetrapyrrole biosynthetic process
0.45	GO:0042168	heme metabolic process
0.45	GO:0046148	pigment biosynthetic process
0.42	GO:0051188	cofactor biosynthetic process

0.80

GO:0004418

hydroxymethylbilane synthase activity

0.37

GO:0005737

cytoplasm

0.80	EC:2.5.1.61	GO:0004418
0.80	KEGG:R00084	GO:0004418

sp|P19357|GTR4_RAT
Solute carrier family 2, facilitated glucose transporter member 4
Search

SLC2A4

0.87	Solute carrier family 2, facilitated glucose transporter member 4

0.77	GO:1904659	glucose transmembrane transport
0.73	GO:0032868	response to insulin
0.68	GO:0071375	cellular response to peptide hormone stimulus
0.56	GO:0010021	amylopectin biosynthetic process
0.55	GO:0050873	brown fat cell differentiation
0.55	GO:0046323	glucose import
0.53	GO:0071356	cellular response to tumor necrosis factor
0.53	GO:0071470	cellular response to osmotic stress
0.52	GO:0042593	glucose homeostasis
0.48	GO:0071548	response to dexamethasone

0.77	GO:0005355	glucose transmembrane transporter activity
0.48	GO:0043621	protein self-association
0.46	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.43	GO:0042802	identical protein binding
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.36	GO:0019900	kinase binding
0.36	GO:0009679	hexose:proton symporter activity

0.57	GO:0032593	insulin-responsive compartment
0.55	GO:0045121	membrane raft
0.54	GO:0042383	sarcolemma
0.52	GO:0070062	extracellular exosome
0.52	GO:0009897	external side of plasma membrane
0.52	GO:0030140	trans-Golgi network transport vesicle
0.52	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0012506	vesicle membrane
0.50	GO:0005887	integral component of plasma membrane
0.49	GO:0005768	endosome

sp|P19359|ASCL1_RAT
Achaete-scute homolog 1
Search

ASCL1

0.29	Transcriptional regulator

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0061549	sympathetic ganglion development
0.59	GO:0035270	endocrine system development
0.59	GO:0030902	hindbrain development
0.58	GO:0003359	noradrenergic neuron fate commitment
0.58	GO:0060165	regulation of timing of subpallium neuron differentiation
0.58	GO:0061103	carotid body glomus cell differentiation
0.58	GO:0061102	stomach neuroendocrine cell differentiation
0.58	GO:0061100	lung neuroendocrine cell differentiation
0.57	GO:0060163	subpallium neuron fate commitment

0.68	GO:0046983	protein dimerization activity
0.58	GO:0070888	E-box binding
0.57	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0043425	bHLH transcription factor binding
0.49	GO:0000989	transcription factor activity, transcription factor binding
0.49	GO:0003682	chromatin binding
0.38	GO:0042802	identical protein binding

0.51	GO:0043025	neuronal cell body
0.47	GO:0090575	RNA polymerase II transcription factor complex
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P19360|ASCL2_RAT
Achaete-scute homolog 2
Search

ASCL2

0.23	Transcriptional regulator

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0060712	spongiotrophoblast layer development
0.54	GO:0030154	cell differentiation
0.54	GO:0007399	nervous system development
0.54	GO:0001666	response to hypoxia
0.54	GO:0035019	somatic stem cell population maintenance
0.53	GO:0051960	regulation of nervous system development
0.53	GO:0060284	regulation of cell development
0.53	GO:0035270	endocrine system development
0.53	GO:0045892	negative regulation of transcription, DNA-templated

0.68	GO:0046983	protein dimerization activity
0.62	GO:0070888	E-box binding
0.60	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0043425	bHLH transcription factor binding
0.45	GO:0000989	transcription factor activity, transcription factor binding
0.44	GO:0003682	chromatin binding
0.36	GO:0042802	identical protein binding

0.49	GO:0090575	RNA polymerase II transcription factor complex
0.45	GO:0043025	neuronal cell body
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P19377|CD3D_RAT
T-cell surface glycoprotein CD3 delta chain
Search

CD3D

0.97	T-cell surface glycoprotein CD3 delta chain

0.71	GO:0007166	cell surface receptor signaling pathway
0.59	GO:0045059	positive thymic T cell selection
0.55	GO:0051260	protein homooligomerization
0.53	GO:0002250	adaptive immune response
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0070228	regulation of lymphocyte apoptotic process
0.45	GO:0007163	establishment or maintenance of cell polarity
0.41	GO:0015031	protein transport
0.40	GO:0031295	T cell costimulation
0.39	GO:0002757	immune response-activating signal transduction

0.70	GO:0004888	transmembrane signaling receptor activity
0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0042803	protein homodimerization activity
0.53	GO:0003713	transcription coactivator activity
0.37	GO:0042608	T cell receptor binding
0.36	GO:0030159	receptor signaling complex scaffold activity

0.77	GO:0042101	T cell receptor complex
0.39	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0005887	integral component of plasma membrane

sp|P19468|GSH1_RAT
Glutamate--cysteine ligase catalytic subunit
Search

GCLC

0.80	Glutamate--cysteine ligase catalytic subunit

0.77	GO:0006750	glutathione biosynthetic process
0.59	GO:0051900	regulation of mitochondrial depolarization
0.58	GO:0008637	apoptotic mitochondrial changes
0.57	GO:0019852	L-ascorbic acid metabolic process
0.57	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.57	GO:0031397	negative regulation of protein ubiquitination
0.57	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0050880	regulation of blood vessel size
0.55	GO:0046685	response to arsenic-containing substance
0.53	GO:0009410	response to xenobiotic stimulus

0.77	GO:0004357	glutamate-cysteine ligase activity
0.60	GO:0016595	glutamate binding
0.52	GO:0043531	ADP binding
0.52	GO:0046982	protein heterodimerization activity
0.47	GO:0000287	magnesium ion binding
0.45	GO:0050662	coenzyme binding
0.34	GO:0005524	ATP binding
0.33	GO:0003676	nucleic acid binding

0.62	GO:0017109	glutamate-cysteine ligase complex
0.49	GO:0005829	cytosol

0.77	EC:6.3.2.2	GO:0004357
0.77	KEGG:R00894	GO:0004357

sp|P19488|UDB37_RAT
UDP-glucuronosyltransferase 2B37
Search

0.53	UDP-glucuronosyltransferase

0.48	GO:0052695	cellular glucuronidation
0.39	GO:0008209	androgen metabolic process
0.38	GO:0071394	cellular response to testosterone stimulus
0.38	GO:0071361	cellular response to ethanol
0.38	GO:0071378	cellular response to growth hormone stimulus
0.38	GO:0071385	cellular response to glucocorticoid stimulus
0.37	GO:0070980	biphenyl catabolic process
0.37	GO:0032496	response to lipopolysaccharide
0.32	GO:0017144	drug metabolic process

0.80	GO:0015020	glucuronosyltransferase activity
0.40	GO:0001972	retinoic acid binding

0.43	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0005740	mitochondrial envelope
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0015020

sp|P19490|GRIA1_RAT
Glutamate receptor 1
Search

GRIA1

0.93	Glutamate ionotropic receptor AMPA type subunit 1

0.79	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.56	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration
0.54	GO:0060292	long term synaptic depression
0.53	GO:0031623	receptor internalization
0.53	GO:0007616	long-term memory
0.37	GO:0060992	response to fungicide
0.37	GO:0010226	response to lithium ion
0.37	GO:0001919	regulation of receptor recycling

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.76	GO:0004970	ionotropic glutamate receptor activity
0.56	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.54	GO:0099094	ligand-gated cation channel activity
0.51	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.38	GO:0001540	amyloid-beta binding
0.38	GO:0030165	PDZ domain binding
0.36	GO:0005272	sodium channel activity
0.36	GO:0098782	mechanosensitived potassium channel activity
0.36	GO:0031698	beta-2 adrenergic receptor binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.58	GO:0032281	AMPA glutamate receptor complex
0.55	GO:0044308	axonal spine
0.55	GO:0032591	dendritic spine membrane
0.53	GO:0014069	postsynaptic density
0.51	GO:0008021	synaptic vesicle
0.51	GO:0055037	recycling endosome
0.51	GO:0043025	neuronal cell body
0.49	GO:0009986	cell surface

sp|P19491|GRIA2_RAT
Glutamate receptor 2
Search

GRIA2

0.93	Glutamate ionotropic receptor AMPA type subunit 2

0.79	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.42	GO:0048899	anterior lateral line development
0.41	GO:0048915	posterior lateral line system development
0.40	GO:0014032	neural crest cell development
0.40	GO:0048701	embryonic cranial skeleton morphogenesis
0.38	GO:0007399	nervous system development
0.35	GO:0060992	response to fungicide
0.35	GO:0010226	response to lithium ion

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.76	GO:0004970	ionotropic glutamate receptor activity
0.46	GO:0099094	ligand-gated cation channel activity
0.38	GO:0005272	sodium channel activity
0.38	GO:0098782	mechanosensitived potassium channel activity
0.37	GO:0001540	amyloid-beta binding
0.35	GO:0016934	extracellularly glycine-gated chloride channel activity
0.35	GO:0005515	protein binding
0.35	GO:0005246	calcium channel regulator activity

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.48	GO:0032281	AMPA glutamate receptor complex
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0099240	intrinsic component of synaptic membrane
0.37	GO:0106003	amyloid-beta complex
0.37	GO:0036477	somatodendritic compartment
0.37	GO:0043005	neuron projection
0.36	GO:0014069	postsynaptic density
0.36	GO:0008021	synaptic vesicle

sp|P19492|GRIA3_RAT
Glutamate receptor 3
Search

GRIA3

0.65	Glutamate ionotropic receptor AMPA type subunit 3

0.79	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.35	GO:0060992	response to fungicide
0.35	GO:0010226	response to lithium ion
0.35	GO:0001919	regulation of receptor recycling

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.76	GO:0004970	ionotropic glutamate receptor activity
0.55	GO:0099094	ligand-gated cation channel activity
0.37	GO:0001540	amyloid-beta binding
0.35	GO:0030165	PDZ domain binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.57	GO:0032281	AMPA glutamate receptor complex
0.35	GO:0043083	synaptic cleft
0.35	GO:0043198	dendritic shaft
0.35	GO:0043204	perikaryon
0.35	GO:0043195	terminal bouton
0.35	GO:0043197	dendritic spine
0.35	GO:0030666	endocytic vesicle membrane
0.35	GO:0014069	postsynaptic density

sp|P19493|GRIA4_RAT
Glutamate receptor 4
Search

GRIA4

0.95	Glutamate ionotropic receptor AMPA type subunit 4

0.78	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.35	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.35	GO:0060992	response to fungicide
0.35	GO:0050803	regulation of synapse structure or activity

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.76	GO:0004970	ionotropic glutamate receptor activity
0.55	GO:0099094	ligand-gated cation channel activity
0.34	GO:0005515	protein binding
0.33	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.32	GO:0000287	magnesium ion binding

0.77	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.47	GO:0032281	AMPA glutamate receptor complex
0.41	GO:0030425	dendrite
0.40	GO:0043025	neuronal cell body
0.39	GO:0032983	kainate selective glutamate receptor complex
0.37	GO:0044309	neuron spine
0.36	GO:1903561	extracellular vesicle
0.35	GO:0043195	terminal bouton
0.35	GO:0030666	endocytic vesicle membrane

0.33

EC:2.7.8.7

GO:0008897

sp|P19511|AT5F1_RAT
ATP synthase F(0) complex subunit B1, mitochondrial
Search

ATP5F1

0.42	ATP synthase peripheral stalk-membrane subunit b

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.43	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0021762	substantia nigra development
0.35	GO:0042407	cristae formation
0.34	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.44	GO:0016887	ATPase activity
0.43	GO:0022853	active ion transmembrane transporter activity
0.42	GO:0015399	primary active transmembrane transporter activity
0.33	GO:0005515	protein binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.50	GO:0043209	myelin sheath
0.46	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.44

GO:0016887

sp|P19527|NFL_RAT
Neurofilament light polypeptide
Search

NEFL

0.97	Neurofilament light polypeptide

0.74	GO:0061564	axon development
0.63	GO:0033693	neurofilament bundle assembly
0.61	GO:0019896	axonal transport of mitochondrion
0.61	GO:0008090	retrograde axonal transport
0.60	GO:0008089	anterograde axonal transport
0.58	GO:0031133	regulation of axon diameter
0.57	GO:0031102	neuron projection regeneration
0.56	GO:0048678	response to axon injury
0.56	GO:0050885	neuromuscular process controlling balance
0.55	GO:0050772	positive regulation of axonogenesis

0.62	GO:0005198	structural molecule activity
0.57	GO:0008022	protein C-terminus binding
0.53	GO:0030674	protein binding, bridging
0.52	GO:0042802	identical protein binding
0.40	GO:0043274	phospholipase binding
0.38	GO:0019904	protein domain specific binding
0.38	GO:0046982	protein heterodimerization activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.85	GO:0005883	neurofilament
0.60	GO:0033596	TSC1-TSC2 complex
0.59	GO:1904115	axon cytoplasm
0.56	GO:0043209	myelin sheath
0.40	GO:0031965	nuclear membrane
0.40	GO:0036464	cytoplasmic ribonucleoprotein granule
0.39	GO:0030426	growth cone
0.38	GO:0005654	nucleoplasm
0.35	GO:0045098	type III intermediate filament

sp|P19627|GNAZ_RAT
Guanine nucleotide-binding protein G(z) subunit alpha
Search

GNAZ

0.97	G protein subunit alpha z

0.73	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.34	GO:0006457	protein folding
0.32	GO:0055085	transmembrane transport

0.76	GO:0031683	G-protein beta/gamma-subunit complex binding
0.64	GO:0003924	GTPase activity
0.62	GO:0032550	purine ribonucleoside binding
0.62	GO:0019001	guanyl nucleotide binding
0.60	GO:0004871	signal transducer activity
0.51	GO:0032555	purine ribonucleotide binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0001664	G-protein coupled receptor binding
0.34	GO:0046872	metal ion binding
0.32	GO:0022857	transmembrane transporter activity

0.50	GO:0030425	dendrite
0.50	GO:0044297	cell body
0.46	GO:1905360	GTPase complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0098797	plasma membrane protein complex
0.37	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005635	nuclear envelope
0.34	GO:0005783	endoplasmic reticulum

sp|P19629|LDHC_RAT
L-lactate dehydrogenase C chain
Search

0.53	L-lactate dehydrogenase C chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0030317	flagellated sperm motility
0.46	GO:1901617	organic hydroxy compound biosynthetic process
0.45	GO:0006754	ATP biosynthetic process
0.42	GO:0016053	organic acid biosynthetic process
0.37	GO:0051591	response to cAMP
0.37	GO:0043627	response to estrogen
0.37	GO:0009749	response to glucose

0.81	GO:0004459	L-lactate dehydrogenase activity
0.41	GO:0045296	cadherin binding
0.40	GO:0042802	identical protein binding
0.36	GO:0019900	kinase binding
0.35	GO:0051287	NAD binding

0.49	GO:0031514	motile cilium
0.48	GO:0005737	cytoplasm
0.40	GO:0045121	membrane raft
0.39	GO:0043209	myelin sheath
0.38	GO:0070062	extracellular exosome
0.36	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0097223	sperm part
0.35	GO:0044441	ciliary part
0.30	GO:0016021	integral component of membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P19633|CASQ1_RAT
Calsequestrin-1
Search

CASQ1

0.90	Calsequestrin

0.57	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
0.56	GO:1901341	positive regulation of store-operated calcium channel activity
0.55	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.55	GO:2001256	regulation of store-operated calcium entry
0.54	GO:0045214	sarcomere organization
0.51	GO:0007029	endoplasmic reticulum organization
0.51	GO:0051258	protein polymerization
0.48	GO:0009408	response to heat
0.40	GO:0014894	response to denervation involved in regulation of muscle adaptation
0.38	GO:0010033	response to organic substance

0.70	GO:0005509	calcium ion binding
0.49	GO:0042802	identical protein binding
0.38	GO:0048306	calcium-dependent protein binding
0.35	GO:0005391	sodium:potassium-exchanging ATPase activity
0.34	GO:0030955	potassium ion binding
0.34	GO:0046983	protein dimerization activity
0.33	GO:0000287	magnesium ion binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.58	GO:0033018	sarcoplasmic reticulum lumen
0.49	GO:0005759	mitochondrial matrix
0.44	GO:0031674	I band
0.43	GO:0014802	terminal cisterna
0.41	GO:0033017	sarcoplasmic reticulum membrane
0.39	GO:0030315	T-tubule
0.38	GO:0030314	junctional membrane complex
0.37	GO:0005794	Golgi apparatus
0.35	GO:0005790	smooth endoplasmic reticulum
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.35

EC:3.6.3.9

GO:0005391

sp|P19637|TPA_RAT
Tissue-type plasminogen activator
Search

PLAT

0.94	Salivary plasminogen activator gamma

0.86	GO:0031639	plasminogen activation
0.63	GO:0014909	smooth muscle cell migration
0.61	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.58	GO:0001666	response to hypoxia
0.54	GO:0045861	negative regulation of proteolysis
0.39	GO:0042060	wound healing
0.39	GO:0071373	cellular response to luteinizing hormone stimulus
0.39	GO:0060279	positive regulation of ovulation
0.38	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.38	GO:0071549	cellular response to dexamethasone stimulus

0.69	GO:0004252	serine-type endopeptidase activity
0.59	GO:0051219	phosphoprotein binding
0.53	GO:0005102	receptor binding
0.38	GO:0097655	serpin family protein binding
0.34	GO:0005509	calcium ion binding

0.65	GO:0005576	extracellular region
0.57	GO:0030141	secretory granule
0.57	GO:0045177	apical part of cell
0.54	GO:0009986	cell surface
0.36	GO:0045202	synapse

0.69

GO:0004252

sp|P19643|AOFB_RAT
Amine oxidase [flavin-containing] B
Search

MAOB

0.49	Amine oxidase [flavin-containing] B

0.52	GO:0055114	oxidation-reduction process
0.51	GO:0042420	dopamine catabolic process
0.41	GO:0042135	neurotransmitter catabolic process
0.39	GO:0014063	negative regulation of serotonin secretion
0.39	GO:0010269	response to selenium ion
0.39	GO:0045964	positive regulation of dopamine metabolic process
0.39	GO:0051412	response to corticosterone
0.39	GO:0010044	response to aluminum ion
0.38	GO:0045471	response to ethanol
0.38	GO:0032496	response to lipopolysaccharide

0.54	GO:0016491	oxidoreductase activity
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0051378	serotonin binding

0.48	GO:0005739	mitochondrion
0.46	GO:0031967	organelle envelope
0.46	GO:0031090	organelle membrane
0.43	GO:0098805	whole membrane
0.41	GO:0019867	outer membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.54

GO:0016491

sp|P19686|GCYA3_RAT
Guanylate cyclase soluble subunit alpha-3
Search

GUCY1A3

0.97	Guanylate cyclase soluble subunit alpha-3

0.80	GO:0006182	cGMP biosynthetic process
0.63	GO:0052565	response to defense-related host nitric oxide production
0.61	GO:0030828	positive regulation of cGMP biosynthetic process
0.61	GO:0035556	intracellular signal transduction
0.61	GO:0060087	relaxation of vascular smooth muscle
0.57	GO:0008217	regulation of blood pressure
0.43	GO:0090594	inflammatory response to wounding
0.35	GO:0009635	response to herbicide
0.35	GO:0006171	cAMP biosynthetic process
0.35	GO:0014070	response to organic cyclic compound

0.81	GO:0004383	guanylate cyclase activity
0.60	GO:0020037	heme binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.47	GO:0004016	adenylate cyclase activity
0.37	GO:0047805	cytidylate cyclase activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0043168	anion binding
0.35	GO:0005515	protein binding
0.33	GO:0004872	receptor activity

0.62	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81	EC:4.6.1.2	GO:0004383
0.37	KEGG:R00574	GO:0047805

sp|P19804|NDKB_RAT
Nucleoside diphosphate kinase B
Search

0.47	Nucleoside diphosphate kinase B

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.48	GO:0050679	positive regulation of epithelial cell proliferation
0.48	GO:0042981	regulation of apoptotic process
0.46	GO:0007595	lactation
0.45	GO:0043388	positive regulation of DNA binding
0.44	GO:2000026	regulation of multicellular organismal development
0.42	GO:0045597	positive regulation of cell differentiation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.45	GO:0043024	ribosomal small subunit binding
0.42	GO:0042802	identical protein binding
0.41	GO:0004536	deoxyribonuclease activity
0.41	GO:0019215	intermediate filament binding
0.40	GO:0046872	metal ion binding

0.49	GO:0001726	ruffle
0.46	GO:0043209	myelin sheath
0.44	GO:0031256	leading edge membrane
0.44	GO:0031253	cell projection membrane
0.44	GO:0030027	lamellipodium
0.42	GO:0005634	nucleus
0.42	GO:0005829	cytosol
0.41	GO:0005925	focal adhesion
0.40	GO:0005739	mitochondrion
0.39	GO:0070062	extracellular exosome

0.79

EC:2.7.4.6

GO:0004550

sp|P19814|TGON3_RAT
Trans-Golgi network integral membrane protein TGN38
Search

TGOLN2

0.96	Trans-Golgi network integral membrane protein 2

0.54	GO:0006895	Golgi to endosome transport
0.40	GO:0043547	positive regulation of GTPase activity
0.37	GO:0060070	canonical Wnt signaling pathway
0.36	GO:0043687	post-translational protein modification
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0061024	membrane organization

0.40	GO:0005096	GTPase activator activity
0.38	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.78	GO:0005802	trans-Golgi network
0.52	GO:0030140	trans-Golgi network transport vesicle
0.51	GO:0005768	endosome
0.47	GO:0005829	cytosol
0.43	GO:0005654	nucleoplasm
0.36	GO:0005886	plasma membrane
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0030665	clathrin-coated vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|P19836|PCY1A_RAT
Choline-phosphate cytidylyltransferase A
Search

PCYT1A

0.97	Choline-phosphate cytidylyltransferase A

0.53	GO:0006656	phosphatidylcholine biosynthetic process
0.34	GO:0001541	ovarian follicle development
0.34	GO:0007283	spermatogenesis

0.55	GO:0016779	nucleotidyltransferase activity
0.38	GO:0031210	phosphatidylcholine binding
0.37	GO:0005516	calmodulin binding
0.37	GO:0042803	protein homodimerization activity

0.56	GO:0042587	glycogen granule
0.47	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0005635	nuclear envelope
0.36	GO:0005829	cytosol
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0005886	plasma membrane

0.55

EC:2.7.7

GO:0016779

sp|P19939|APOC1_RAT
Apolipoprotein C-I
Search

APOC1

0.97	Apolipoprotein C-I

0.75	GO:0042157	lipoprotein metabolic process
0.68	GO:0010900	negative regulation of phosphatidylcholine catabolic process
0.66	GO:0034447	very-low-density lipoprotein particle clearance
0.66	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.66	GO:0006869	lipid transport
0.66	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.65	GO:0051005	negative regulation of lipoprotein lipase activity
0.65	GO:0010985	negative regulation of lipoprotein particle clearance
0.64	GO:0032375	negative regulation of cholesterol transport
0.64	GO:0048261	negative regulation of receptor-mediated endocytosis

0.63	GO:0004859	phospholipase inhibitor activity
0.62	GO:0005504	fatty acid binding
0.39	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.39	GO:0031210	phosphatidylcholine binding

0.70	GO:0034361	very-low-density lipoprotein particle
0.62	GO:0034364	high-density lipoprotein particle
0.52	GO:0005783	endoplasmic reticulum
0.42	GO:0070062	extracellular exosome
0.39	GO:0042627	chylomicron

sp|P19944|RLA1_RAT
60S acidic ribosomal protein P1
Search

RPLP1

0.73	Ribosomal protein lateral stalk subunit P1

0.69	GO:0006414	translational elongation
0.50	GO:0032147	activation of protein kinase activity
0.49	GO:0002181	cytoplasmic translation
0.44	GO:0030218	erythrocyte differentiation
0.36	GO:0006417	regulation of translation
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0034250	positive regulation of cellular amide metabolic process
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.51	GO:0030295	protein kinase activator activity
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0005515	protein binding
0.32	GO:0003777	microtubule motor activity
0.32	GO:0016740	transferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0008144	drug binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|P19945|RLA0_RAT
60S acidic ribosomal protein P0
Search

RPLP0

0.67	60S acidic ribosomal protein P0

0.66	GO:0042254	ribosome biogenesis
0.48	GO:0071353	cellular response to interleukin-4
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0010269	response to selenium ion
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.35	GO:0007595	lactation
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0043009	chordate embryonic development

0.43	GO:0003735	structural constituent of ribosome
0.34	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.60	GO:0005840	ribosome
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.46	GO:0044445	cytosolic part
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0030425	dendrite
0.43	GO:0005634	nucleus
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P19969|GBRA5_RAT
Gamma-aminobutyric acid receptor subunit alpha-5
Search

GABRA5

0.95	Gamma-aminobutyric acid receptor subunit alpha-5

0.85	GO:0007214	gamma-aminobutyric acid signaling pathway
0.76	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.53	GO:0060384	innervation
0.52	GO:0001662	behavioral fear response
0.52	GO:0090102	cochlea development
0.52	GO:0060119	inner ear receptor cell development
0.51	GO:0008306	associative learning
0.51	GO:0043524	negative regulation of neuron apoptotic process
0.50	GO:0007605	sensory perception of sound

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.42	GO:0005254	chloride channel activity
0.40	GO:0099095	ligand-gated anion channel activity
0.38	GO:0050811	GABA receptor binding
0.38	GO:0008503	benzodiazepine receptor activity
0.38	GO:0022835	transmitter-gated channel activity
0.36	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

0.56	GO:0005886	plasma membrane
0.55	GO:0030425	dendrite
0.55	GO:0044297	cell body
0.54	GO:1902711	GABA-A receptor complex
0.49	GO:0060077	inhibitory synapse
0.48	GO:0098794	postsynapse
0.46	GO:0030424	axon
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:0034707	chloride channel complex

sp|P19999|MBL1_RAT
Mannose-binding protein A
Search

MBL2

0.85	Pulmonary surfactant-associated protein A

0.86	GO:0001867	complement activation, lectin pathway
0.52	GO:0044130	negative regulation of growth of symbiont in host
0.51	GO:0006958	complement activation, classical pathway
0.51	GO:0050830	defense response to Gram-positive bacterium
0.49	GO:0048525	negative regulation of viral process
0.47	GO:0051873	killing by host of symbiont cells
0.46	GO:0050766	positive regulation of phagocytosis
0.38	GO:0070207	protein homotrimerization
0.36	GO:0051289	protein homotetramerization
0.36	GO:0008228	opsonization

0.85	GO:0005537	mannose binding
0.50	GO:0048306	calcium-dependent protein binding
0.45	GO:0005102	receptor binding
0.43	GO:0005509	calcium ion binding
0.38	GO:0005201	extracellular matrix structural constituent
0.38	GO:0002020	protease binding
0.37	GO:0070273	phosphatidylinositol-4-phosphate binding
0.36	GO:0001871	pattern binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0043621	protein self-association

0.72	GO:0005581	collagen trimer
0.50	GO:0005576	extracellular region
0.34	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004252

sp|P20037|HA2B_RAT
Rano class II histocompatibility antigen, B alpha chain
Search

0.42	Major histocompatibility complex class II DQ alpha chain

0.82	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.47	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.46	GO:0045582	positive regulation of T cell differentiation
0.39	GO:0034097	response to cytokine
0.38	GO:0006952	defense response
0.35	GO:0071385	cellular response to glucocorticoid stimulus
0.35	GO:0042130	negative regulation of T cell proliferation
0.35	GO:0031295	T cell costimulation
0.35	GO:0050852	T cell receptor signaling pathway

0.47	GO:0042605	peptide antigen binding
0.38	GO:0005515	protein binding
0.35	GO:0032395	MHC class II receptor activity

0.75	GO:0042613	MHC class II protein complex
0.45	GO:0009897	external side of plasma membrane
0.44	GO:0005764	lysosome
0.35	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.35	GO:0032588	trans-Golgi network membrane
0.34	GO:0030669	clathrin-coated endocytic vesicle membrane
0.34	GO:0012507	ER to Golgi transport vesicle membrane
0.34	GO:0098852	lytic vacuole membrane
0.34	GO:0010008	endosome membrane
0.33	GO:0005887	integral component of plasma membrane

sp|P20059|HEMO_RAT
Hemopexin
Search

HPX

0.93

Hemopexin

0.77	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin
0.77	GO:0060332	positive regulation of response to interferon-gamma
0.75	GO:0020027	hemoglobin metabolic process
0.75	GO:0060334	regulation of interferon-gamma-mediated signaling pathway
0.74	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.73	GO:0002639	positive regulation of immunoglobulin production
0.73	GO:0015886	heme transport
0.73	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.73	GO:0006879	cellular iron ion homeostasis
0.61	GO:0042168	heme metabolic process

0.74	GO:0015232	heme transporter activity
0.54	GO:0046872	metal ion binding
0.38	GO:0004415	hyalurononglucosaminidase activity
0.37	GO:0020037	heme binding
0.35	GO:0005515	protein binding

0.62	GO:0005615	extracellular space
0.42	GO:1903561	extracellular vesicle
0.40	GO:0071682	endocytic vesicle lumen
0.30	GO:0016020	membrane

0.38

EC:3.2.1.35

GO:0004415

sp|P20068|NEUT_RAT
Neurotensin/neuromedin N
Search

NTS

0.97	Neurotensin/neuromedin N

0.76	GO:0010469	regulation of receptor activity
0.43	GO:0050880	regulation of blood vessel size
0.38	GO:0097332	response to antipsychotic drug
0.38	GO:0051412	response to corticosterone
0.38	GO:0071285	cellular response to lithium ion
0.38	GO:0071549	cellular response to dexamethasone stimulus
0.38	GO:0001975	response to amphetamine
0.37	GO:1990090	cellular response to nerve growth factor stimulus
0.37	GO:0042220	response to cocaine
0.37	GO:0048678	response to axon injury

0.85

GO:0005184

neuropeptide hormone activity

0.66	GO:0005576	extracellular region
0.51	GO:0043679	axon terminus
0.42	GO:0030133	transport vesicle
0.36	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|P20069|MPPA_RAT
Mitochondrial-processing peptidase subunit alpha
Search

PMPCA

0.88	Mitochondrial-processing peptidase subunit alpha

0.80	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.35	GO:0006851	mitochondrial calcium ion transmembrane transport

0.65	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding

0.59	GO:0005739	mitochondrion
0.47	GO:0019866	organelle inner membrane
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0005615	extracellular space

0.65

GO:0004222

sp|P20070|NB5R3_RAT
NADH-cytochrome b5 reductase 3
Search

CYB5R3

0.64	NADH-cytochrome b5 reductase

0.52	GO:0055114	oxidation-reduction process
0.42	GO:0006695	cholesterol biosynthetic process
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0008015	blood circulation
0.34	GO:0006805	xenobiotic metabolic process
0.33	GO:0006508	proteolysis

0.80	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
0.37	GO:0016208	AMP binding
0.37	GO:0043531	ADP binding
0.37	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0051287	NAD binding
0.34	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity

0.50	GO:0005811	lipid droplet
0.47	GO:0005783	endoplasmic reticulum
0.44	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.40	GO:0031968	organelle outer membrane
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.38	GO:0070062	extracellular exosome
0.35	GO:0035578	azurophil granule lumen
0.35	GO:0005833	hemoglobin complex

0.80

EC:1.6.2.2

GO:0004128

sp|P20096|IL4_RAT
Interleukin-4
Search

IL4

0.65	Interleukin-4

0.78	GO:0042113	B cell activation
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.62	GO:0070351	negative regulation of white fat cell proliferation
0.60	GO:1903660	negative regulation of complement-dependent cytotoxicity
0.59	GO:0031296	B cell costimulation
0.59	GO:0048295	positive regulation of isotype switching to IgE isotypes
0.58	GO:0045348	positive regulation of MHC class II biosynthetic process
0.58	GO:2000320	negative regulation of T-helper 17 cell differentiation
0.58	GO:0045080	positive regulation of chemokine biosynthetic process

0.86	GO:0005136	interleukin-4 receptor binding
0.78	GO:0008083	growth factor activity
0.75	GO:0005125	cytokine activity

0.68	GO:0005615	extracellular space
0.54	GO:0009897	external side of plasma membrane

sp|P20156|VGF_RAT
Neurosecretory protein VGF
Search

VGF

0.96	VGF nerve growth factor inducible

0.75	GO:0010469	regulation of receptor activity
0.66	GO:0002021	response to dietary excess
0.65	GO:0051591	response to cAMP
0.65	GO:0030073	insulin secretion
0.64	GO:0001541	ovarian follicle development
0.63	GO:0033500	carbohydrate homeostasis
0.62	GO:0032868	response to insulin
0.61	GO:0009409	response to cold
0.58	GO:0019953	sexual reproduction
0.54	GO:0048167	regulation of synaptic plasticity

0.85	GO:0005184	neuropeptide hormone activity
0.44	GO:0008083	growth factor activity
0.32	GO:0016788	hydrolase activity, acting on ester bonds
0.31	GO:0140098	catalytic activity, acting on RNA
0.31	GO:0003723	RNA binding
0.31	GO:0140096	catalytic activity, acting on a protein

0.59	GO:0005615	extracellular space
0.57	GO:0031410	cytoplasmic vesicle
0.55	GO:0005794	Golgi apparatus
0.39	GO:0043025	neuronal cell body
0.39	GO:0005788	endoplasmic reticulum lumen
0.39	GO:0043005	neuron projection
0.38	GO:0012506	vesicle membrane
0.38	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.33	GO:0005634	nucleus

0.32

EC:3.1

GO:0016788

sp|P20171|RASH_RAT
GTPase HRas
Search

HRAS

0.53	V-Ha-ras Harvey rat sarcoma viral oncogene homolog a

0.61	GO:0007165	signal transduction
0.55	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.53	GO:2000630	positive regulation of miRNA metabolic process
0.53	GO:0043524	negative regulation of neuron apoptotic process
0.52	GO:1900029	positive regulation of ruffle assembly
0.52	GO:0008284	positive regulation of cell proliferation
0.52	GO:0090398	cellular senescence
0.52	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.51	GO:0071480	cellular response to gamma radiation
0.51	GO:0001934	positive regulation of protein phosphorylation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.51	GO:0019003	GDP binding
0.50	GO:0008022	protein C-terminus binding
0.41	GO:0032403	protein complex binding
0.37	GO:0019002	GMP binding
0.36	GO:0030275	LRR domain binding
0.33	GO:0042802	identical protein binding
0.33	GO:0005198	structural molecule activity
0.32	GO:0030554	adenyl nucleotide binding

0.46	GO:0005794	Golgi apparatus
0.42	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.36	GO:0020002	host cell plasma membrane
0.35	GO:0098857	membrane microdomain
0.34	GO:0005829	cytosol
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005925	focal adhesion
0.33	GO:0005739	mitochondrion

sp|P20236|GBRA3_RAT
Gamma-aminobutyric acid receptor subunit alpha-3
Search

GABRA3

0.97	Gamma-aminobutyric acid receptor subunit alpha-3

0.68	GO:0007214	gamma-aminobutyric acid signaling pathway
0.61	GO:0006821	chloride transport
0.58	GO:0034220	ion transmembrane transport
0.37	GO:0060384	innervation
0.37	GO:0001662	behavioral fear response
0.37	GO:0090102	cochlea development
0.37	GO:0060119	inner ear receptor cell development
0.37	GO:0008306	associative learning
0.37	GO:0043524	negative regulation of neuron apoptotic process
0.36	GO:0007605	sensory perception of sound

0.81	GO:0004890	GABA-A receptor activity
0.73	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0005254	chloride channel activity
0.36	GO:0008503	benzodiazepine receptor activity
0.34	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.48	GO:1902711	GABA-A receptor complex
0.39	GO:0034707	chloride channel complex
0.39	GO:0098794	postsynapse
0.38	GO:0030054	cell junction
0.36	GO:0030425	dendrite
0.36	GO:0044297	cell body
0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol

sp|P20266|PO4F1_RAT
POU domain, class 4, transcription factor 1
Search

POU4F1

0.95	POU domain, class 4, transcription factor 1

0.58	GO:0045672	positive regulation of osteoclast differentiation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0050885	neuromuscular process controlling balance
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048513	animal organ development
0.54	GO:0007399	nervous system development
0.54	GO:0007600	sensory perception
0.53	GO:1902867	negative regulation of retina development in camera-type eye

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003714	transcription corepressor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003682	chromatin binding
0.50	GO:0003690	double-stranded DNA binding
0.48	GO:0035326	enhancer binding
0.47	GO:0003713	transcription coactivator activity
0.44	GO:0003697	single-stranded DNA binding
0.44	GO:0051020	GTPase binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.45	GO:0043005	neuron projection
0.44	GO:0000785	chromatin
0.39	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P20267|PO3F1_RAT
POU domain, class 3, transcription factor 1
Search

POU3F1

0.96	POU domain, class 3, transcription factor 1

0.76	GO:0007420	brain development
0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.53	GO:0022008	neurogenesis
0.52	GO:0032292	peripheral nervous system axon ensheathment
0.51	GO:0030216	keratinocyte differentiation
0.51	GO:0007422	peripheral nervous system development
0.51	GO:0042552	myelination
0.50	GO:2001054	negative regulation of mesenchymal cell apoptotic process
0.49	GO:0090103	cochlea morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0001105	RNA polymerase II transcription coactivator activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part

sp|P20272|CNR1_RAT
Cannabinoid receptor 1
Search

CNR1

0.91	Cannabinoid receptor

0.86	GO:0038171	cannabinoid signaling pathway
0.58	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.55	GO:0099553	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
0.52	GO:0007413	axonal fasciculation
0.49	GO:0042593	glucose homeostasis
0.41	GO:0033602	negative regulation of dopamine secretion
0.41	GO:0060405	regulation of penile erection
0.41	GO:0051966	regulation of synaptic transmission, glutamatergic
0.40	GO:0031999	negative regulation of fatty acid beta-oxidation
0.40	GO:0031622	positive regulation of fever generation

0.86	GO:0004949	cannabinoid receptor activity
0.36	GO:1904483	synthetic cannabinoid binding
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.52	GO:0042734	presynaptic membrane
0.51	GO:0030426	growth cone
0.50	GO:0030424	axon
0.40	GO:0005741	mitochondrial outer membrane
0.39	GO:0098857	membrane microdomain
0.35	GO:0030175	filopodium
0.34	GO:0044297	cell body
0.33	GO:0005887	integral component of plasma membrane

sp|P20280|RL21_RAT
60S ribosomal protein L21
Search

RPL21

0.70	Ribosomal protein L21

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.35	GO:0019083	viral transcription
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.42	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0016787

sp|P20289|VEGP1_RAT
Von Ebner gland protein 1
Search

LCN1

0.97	von Ebner gland protein 1

0.50	GO:0050909	sensory perception of taste
0.46	GO:0001895	retina homeostasis
0.40	GO:0050896	response to stimulus
0.39	GO:0015909	long-chain fatty acid transport
0.38	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0006508	proteolysis

0.51	GO:0036094	small molecule binding
0.50	GO:0031404	chloride ion binding
0.44	GO:0005102	receptor binding
0.42	GO:0043621	protein self-association
0.41	GO:0008270	zinc ion binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0004869	cysteine-type endopeptidase inhibitor activity

0.46	GO:0005576	extracellular region
0.42	GO:0031982	vesicle

sp|P20291|AL5AP_RAT
Arachidonate 5-lipoxygenase-activating protein
Search

ALOX5AP

0.97	Arachidonate 5-lipoxygenase-activating protein isoform 1

0.86	GO:0006691	leukotriene metabolic process
0.73	GO:0043085	positive regulation of catalytic activity
0.66	GO:0002540	leukotriene production involved in inflammatory response
0.65	GO:0046456	icosanoid biosynthetic process
0.44	GO:0001525	angiogenesis
0.42	GO:0019372	lipoxygenase pathway
0.42	GO:0070207	protein homotrimerization
0.40	GO:0002675	positive regulation of acute inflammatory response
0.40	GO:0071277	cellular response to calcium ion
0.37	GO:2001300	lipoxin metabolic process

0.75	GO:0008047	enzyme activator activity
0.54	GO:0004464	leukotriene-C4 synthase activity
0.49	GO:0050544	arachidonic acid binding
0.49	GO:0004364	glutathione transferase activity
0.49	GO:0004602	glutathione peroxidase activity
0.41	GO:0004051	arachidonate 5-lipoxygenase activity
0.40	GO:0047485	protein N-terminus binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0019899	enzyme binding

0.49	GO:0005634	nucleus
0.47	GO:0005783	endoplasmic reticulum
0.43	GO:0031967	organelle envelope
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.37	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.54	EC:4.4.1.20	GO:0004464
0.54	KEGG:R03059	GO:0004464

sp|P20294|CNTF_RAT
Ciliary neurotrophic factor
Search

CNTF

0.97	Ciliary neurotrophic factor

0.78	GO:0040007	growth
0.75	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway
0.72	GO:0046533	negative regulation of photoreceptor cell differentiation
0.72	GO:0046668	regulation of retinal cell programmed cell death
0.71	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.69	GO:0043524	negative regulation of neuron apoptotic process
0.69	GO:0048644	muscle organ morphogenesis
0.65	GO:0008284	positive regulation of cell proliferation
0.64	GO:0010469	regulation of receptor activity
0.63	GO:0048666	neuron development

0.72	GO:0005138	interleukin-6 receptor binding
0.66	GO:0008083	growth factor activity
0.57	GO:0005127	ciliary neurotrophic factor receptor binding
0.52	GO:0005125	cytokine activity
0.37	GO:0019888	protein phosphatase regulator activity
0.33	GO:0003676	nucleic acid binding

0.75	GO:0097058	CRLF-CLCF1 complex
0.52	GO:0030424	axon
0.49	GO:0005737	cytoplasm
0.38	GO:0043025	neuronal cell body
0.37	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0000159	protein phosphatase type 2A complex
0.35	GO:0005634	nucleus

sp|P20395|FSHR_RAT
Follicle-stimulating hormone receptor
Search

FSHR

0.83	Follicle-stimulating hormone receptor

0.86	GO:0042699	follicle-stimulating hormone signaling pathway
0.64	GO:0001545	primary ovarian follicle growth
0.60	GO:0060408	regulation of acetylcholine metabolic process
0.59	GO:0045670	regulation of osteoclast differentiation
0.59	GO:0060011	Sertoli cell proliferation
0.58	GO:0009992	cellular water homeostasis
0.58	GO:0035093	spermatogenesis, exchange of chromosomal proteins
0.58	GO:0045779	negative regulation of bone resorption
0.58	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.58	GO:0060009	Sertoli cell development

0.86	GO:0004963	follicle-stimulating hormone receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.45	GO:0001653	peptide receptor activity
0.41	GO:0017046	peptide hormone binding
0.35	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.51	GO:0009986	cell surface
0.39	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

sp|P20411|FCERG_RAT
High affinity immunoglobulin epsilon receptor subunit gamma
Search

FCER1G

0.97	High affinity immunoglobulin epsilon receptor subunit gamma

0.72	GO:0001812	positive regulation of type I hypersensitivity
0.72	GO:0001805	positive regulation of type III hypersensitivity
0.72	GO:0032765	positive regulation of mast cell cytokine production
0.72	GO:0033026	negative regulation of mast cell apoptotic process
0.72	GO:0002894	positive regulation of type II hypersensitivity
0.72	GO:0001796	regulation of type IIa hypersensitivity
0.71	GO:0002554	serotonin secretion by platelet
0.70	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.70	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
0.69	GO:0033008	positive regulation of mast cell activation involved in immune response

0.72	GO:0019767	IgE receptor activity
0.72	GO:0019863	IgE binding
0.70	GO:0019864	IgG binding
0.58	GO:0042803	protein homodimerization activity
0.38	GO:0048038	quinone binding
0.38	GO:0051287	NAD binding
0.37	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.71	GO:0032997	Fc receptor complex
0.63	GO:0009897	external side of plasma membrane
0.54	GO:0005887	integral component of plasma membrane
0.40	GO:0101003	ficolin-1-rich granule membrane
0.39	GO:0070821	tertiary granule membrane
0.38	GO:0098857	membrane microdomain

0.37

EC:1.6

GO:0016651

sp|P20417|PTN1_RAT
Tyrosine-protein phosphatase non-receptor type 1
Search

PTPN1

0.75	Tyrosine-protein phosphatase non-receptor type

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:1903898	negative regulation of PERK-mediated unfolded protein response
0.58	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway
0.57	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway
0.57	GO:2000646	positive regulation of receptor catabolic process
0.57	GO:0036498	IRE1-mediated unfolded protein response
0.56	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.56	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.55	GO:0007257	activation of JUN kinase activity
0.55	GO:0008286	insulin receptor signaling pathway

0.75	GO:0004725	protein tyrosine phosphatase activity
0.55	GO:0030971	receptor tyrosine kinase binding
0.55	GO:0046875	ephrin receptor binding
0.52	GO:0045296	cadherin binding
0.44	GO:0008270	zinc ion binding
0.41	GO:0005158	insulin receptor binding
0.41	GO:0051721	protein phosphatase 2A binding
0.37	GO:0097677	STAT family protein binding
0.35	GO:0005178	integrin binding
0.35	GO:0019905	syntaxin binding

0.57	GO:0097443	sorting endosome
0.55	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane
0.52	GO:0005769	early endosome
0.41	GO:0005886	plasma membrane
0.38	GO:0005829	cytosol
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:0031225	anchored component of membrane
0.34	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.75

GO:0004725

sp|P20420|ACHA5_RAT
Neuronal acetylcholine receptor subunit alpha-5
Search

CHRNA5

0.92	Neuronal acetylcholine receptor subunit alpha-5

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.52	GO:0035094	response to nicotine
0.48	GO:0007271	synaptic transmission, cholinergic
0.48	GO:0007274	neuromuscular synaptic transmission
0.45	GO:0030534	adult behavior
0.38	GO:0006812	cation transport

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.69	GO:0004888	transmembrane signaling receptor activity
0.49	GO:0042166	acetylcholine binding
0.37	GO:0005515	protein binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.51	GO:0005892	acetylcholine-gated channel complex
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite

sp|P20428|MYOG_RAT
Myogenin
Search

MYOG

0.77	Myogenic factor MYOG

0.81	GO:0007517	muscle organ development
0.63	GO:0014737	positive regulation of muscle atrophy
0.63	GO:0048743	positive regulation of skeletal muscle fiber development
0.62	GO:0014894	response to denervation involved in regulation of muscle adaptation
0.62	GO:1901739	regulation of myoblast fusion
0.62	GO:0014891	striated muscle atrophy
0.61	GO:0045663	positive regulation of myoblast differentiation
0.61	GO:0071285	cellular response to lithium ion
0.61	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.60	GO:0071392	cellular response to estradiol stimulus

0.68	GO:0046983	protein dimerization activity
0.59	GO:0070888	E-box binding
0.57	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0031490	chromatin DNA binding
0.57	GO:0001047	core promoter binding
0.55	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.40	GO:0032993	protein-DNA complex
0.35	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.33

GO:0004725

sp|P20595|GCYB1_RAT
Guanylate cyclase soluble subunit beta-1
Search

GUCY1B3

0.95	Guanylate cyclase soluble subunit beta-1

0.81	GO:0006182	cGMP biosynthetic process
0.61	GO:0035556	intracellular signal transduction
0.56	GO:0099555	trans-synaptic signaling by nitric oxide, modulating synaptic transmission
0.41	GO:0071732	cellular response to nitric oxide
0.36	GO:0006171	cAMP biosynthetic process
0.35	GO:0008015	blood circulation

0.81	GO:0004383	guanylate cyclase activity
0.62	GO:0020037	heme binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.46	GO:0004016	adenylate cyclase activity
0.40	GO:0047805	cytidylate cyclase activity
0.38	GO:0051879	Hsp90 protein binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0046872	metal ion binding

0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.38	GO:0048786	presynaptic active zone
0.30	GO:0016021	integral component of membrane

0.81	EC:4.6.1.2	GO:0004383
0.40	KEGG:R00574	GO:0047805

sp|P20607|IL6_RAT
Interleukin-6
Search

IL6

0.70	Interleukin-6

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.68	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment
0.68	GO:0070091	glucagon secretion
0.66	GO:0001781	neutrophil apoptotic process
0.65	GO:0045079	negative regulation of chemokine biosynthetic process
0.65	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.64	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.64	GO:2000553	positive regulation of T-helper 2 cell cytokine production
0.64	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis

0.86	GO:0005138	interleukin-6 receptor binding
0.80	GO:0005125	cytokine activity
0.51	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.58	GO:0009897	external side of plasma membrane
0.52	GO:0005896	interleukin-6 receptor complex
0.38	GO:0005737	cytoplasm

sp|P20611|PPAL_RAT
Lysosomal acid phosphatase
Search

ACP2

0.84	Lysosomal acid phosphatase

0.57	GO:0007040	lysosome organization
0.55	GO:0001501	skeletal system development
0.50	GO:0016311	dephosphorylation
0.36	GO:0048102	autophagic cell death
0.35	GO:0007268	chemical synaptic transmission
0.34	GO:0010033	response to organic substance
0.34	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.34	GO:0051930	regulation of sensory perception of pain
0.34	GO:0046085	adenosine metabolic process
0.34	GO:0051289	protein homotetramerization

0.55	GO:0003993	acid phosphatase activity
0.36	GO:0001784	phosphotyrosine residue binding
0.34	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0052642	lysophosphatidic acid phosphatase activity
0.33	GO:0008253	5'-nucleotidase activity
0.33	GO:0042803	protein homodimerization activity

0.55	GO:0005764	lysosome
0.43	GO:0005775	vacuolar lumen
0.42	GO:0098852	lytic vacuole membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0120025	plasma membrane bounded cell projection
0.35	GO:0097458	neuron part
0.34	GO:0031410	cytoplasmic vesicle
0.33	GO:0012506	vesicle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.55

EC:3.1.3.2

GO:0003993

sp|P20646|PPAP_RAT
Prostatic acid phosphatase
Search

ACPP

0.85	Prostatic acid phosphatase

0.66	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.64	GO:0051930	regulation of sensory perception of pain
0.62	GO:0046085	adenosine metabolic process
0.57	GO:0051289	protein homotetramerization
0.53	GO:0006772	thiamine metabolic process
0.53	GO:0016311	dephosphorylation
0.51	GO:0006144	purine nucleobase metabolic process
0.44	GO:0009117	nucleotide metabolic process
0.41	GO:0007040	lysosome organization
0.41	GO:0001501	skeletal system development

0.67	GO:0052642	lysophosphatidic acid phosphatase activity
0.65	GO:0042131	thiamine phosphate phosphatase activity
0.57	GO:0008253	5'-nucleotidase activity
0.52	GO:0042803	protein homodimerization activity
0.36	GO:0033265	choline binding
0.34	GO:0001784	phosphotyrosine residue binding
0.33	GO:0004721	phosphoprotein phosphatase activity

0.56	GO:0030175	filopodium
0.55	GO:0012506	vesicle membrane
0.55	GO:0005615	extracellular space
0.45	GO:0005886	plasma membrane
0.44	GO:0005764	lysosome
0.41	GO:0098852	lytic vacuole membrane
0.38	GO:1903561	extracellular vesicle
0.38	GO:0005775	vacuolar lumen
0.37	GO:0030141	secretory granule
0.36	GO:0005771	multivesicular body

0.57

EC:3.1.3.5

GO:0008253

sp|P20650|PPM1A_RAT
Protein phosphatase 1A
Search

0.95	LOW QUALITY PROTEIN: protein phosphatase 1A

0.68	GO:0006470	protein dephosphorylation
0.58	GO:0010991	negative regulation of SMAD protein complex assembly
0.57	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.55	GO:0006499	N-terminal protein myristoylation
0.55	GO:0046827	positive regulation of protein export from nucleus
0.54	GO:0030514	negative regulation of BMP signaling pathway
0.54	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.54	GO:0030177	positive regulation of Wnt signaling pathway
0.53	GO:0071560	cellular response to transforming growth factor beta stimulus
0.51	GO:0016055	Wnt signaling pathway

0.73	GO:0004722	protein serine/threonine phosphatase activity
0.68	GO:0030145	manganese ion binding
0.61	GO:0000287	magnesium ion binding
0.57	GO:0070412	R-SMAD binding
0.36	GO:0004871	signal transducer activity
0.35	GO:0008022	protein C-terminus binding
0.32	GO:0003677	DNA binding

0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.34	GO:0034704	calcium channel complex
0.34	GO:0043005	neuron projection
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|P20651|PP2BB_RAT
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
Search

PPP3CB

0.50	Serine/threonine-protein phosphatase

0.71	GO:0006470	protein dephosphorylation
0.57	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.56	GO:0031987	locomotion involved in locomotory behavior
0.56	GO:0035690	cellular response to drug
0.56	GO:0033173	calcineurin-NFAT signaling cascade
0.55	GO:0001946	lymphangiogenesis
0.55	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.54	GO:0043029	T cell homeostasis
0.54	GO:0035176	social behavior
0.53	GO:0030217	T cell differentiation

0.72	GO:0004721	phosphoprotein phosphatase activity
0.62	GO:0030346	protein phosphatase 2B binding
0.55	GO:0005516	calmodulin binding
0.51	GO:0005509	calcium ion binding
0.46	GO:0046983	protein dimerization activity
0.42	GO:0008144	drug binding
0.35	GO:0019855	calcium channel inhibitor activity

0.61	GO:0005955	calcineurin complex
0.54	GO:0030315	T-tubule
0.53	GO:0030018	Z disc
0.36	GO:0005829	cytosol
0.35	GO:0043204	perikaryon
0.34	GO:0030424	axon
0.34	GO:0005654	nucleoplasm
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0004721

sp|P20673|ARLY_RAT
Argininosuccinate lyase
Search

ASL

0.44	Argininosuccinate lyase

0.77	GO:0042450	arginine biosynthetic process via ornithine
0.52	GO:0019676	ammonia assimilation cycle
0.49	GO:0007626	locomotory behavior
0.48	GO:0009791	post-embryonic development
0.42	GO:0000050	urea cycle
0.36	GO:0000053	argininosuccinate metabolic process
0.36	GO:0060539	diaphragm development
0.36	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0007494	midgut development
0.36	GO:0071549	cellular response to dexamethasone stimulus

0.79	GO:0004056	argininosuccinate lyase activity
0.40	GO:0005212	structural constituent of eye lens
0.37	GO:0042802	identical protein binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0003723	RNA binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.37	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0070852	cell body fiber
0.35	GO:0043204	perikaryon
0.35	GO:0031968	organelle outer membrane
0.34	GO:0012505	endomembrane system
0.33	GO:0005634	nucleus

0.79

EC:4.3.2.1

GO:0004056

sp|P20689|MYLK2_RAT
Myosin light chain kinase 2, skeletal/cardiac muscle
Search

MYLK2

0.95	Gallus domesticus skeletal muscle mRNA

0.63	GO:0006468	protein phosphorylation
0.62	GO:0032971	regulation of muscle filament sliding
0.60	GO:0014816	skeletal muscle satellite cell differentiation
0.59	GO:0018210	peptidyl-threonine modification
0.58	GO:0007274	neuromuscular synaptic transmission
0.58	GO:0048738	cardiac muscle tissue development
0.57	GO:0060415	muscle tissue morphogenesis
0.57	GO:0006941	striated muscle contraction
0.55	GO:0003007	heart morphogenesis
0.51	GO:0010628	positive regulation of gene expression

0.65	GO:0004687	myosin light chain kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0004683	calmodulin-dependent protein kinase activity
0.41	GO:0005516	calmodulin binding
0.37	GO:0032027	myosin light chain binding

0.45	GO:0005634	nucleus
0.41	GO:0015629	actin cytoskeleton
0.41	GO:0005737	cytoplasm
0.37	GO:0043195	terminal bouton
0.36	GO:0043197	dendritic spine
0.36	GO:0014069	postsynaptic density
0.36	GO:0043025	neuronal cell body
0.35	GO:0012505	endomembrane system
0.35	GO:0097708	intracellular vesicle
0.34	GO:0099512	supramolecular fiber

0.65

EC:2.7.11.18

GO:0004687

sp|P20695|IFRD1_RAT
Interferon-related developmental regulator 1
Search

IFRD1

0.94	Interferon-related developmental regulator 1

0.86	GO:0048671	negative regulation of collateral sprouting
0.86	GO:0043403	skeletal muscle tissue regeneration
0.85	GO:0030517	negative regulation of axon extension
0.80	GO:0014706	striated muscle tissue development
0.80	GO:0042692	muscle cell differentiation
0.43	GO:0051091	positive regulation of DNA binding transcription factor activity
0.42	GO:0007518	myoblast fate determination
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0014009	glial cell proliferation
0.40	GO:0007405	neuroblast proliferation

0.46

GO:0061629

RNA polymerase II sequence-specific DNA binding transcription factor binding

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.35	GO:0005886	plasma membrane

sp|P20717|PADI2_RAT
Protein-arginine deiminase type-2
Search

PADI2

0.97	Peptidyl arginine deiminase 2

0.80	GO:0018101	protein citrullination
0.60	GO:0010848	regulation of chromatin disassembly
0.60	GO:1901624	negative regulation of lymphocyte chemotaxis
0.59	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.58	GO:0048096	chromatin-mediated maintenance of transcription
0.58	GO:0030520	intracellular estrogen receptor signaling pathway
0.55	GO:1990823	response to leukemia inhibitory factor
0.54	GO:0016570	histone modification
0.52	GO:0071345	cellular response to cytokine stimulus
0.40	GO:0019546	arginine deiminase pathway

0.79	GO:0004668	protein-arginine deiminase activity
0.68	GO:0005509	calcium ion binding
0.57	GO:0030331	estrogen receptor binding
0.40	GO:0016990	arginine deiminase activity
0.38	GO:0034618	arginine binding
0.37	GO:0042803	protein homodimerization activity

0.56	GO:0035327	transcriptionally active chromatin
0.48	GO:0005737	cytoplasm
0.43	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.38	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex
0.34	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system

0.79

EC:3.5.3.15

GO:0004668

sp|P20720|UD12_RAT
UDP-glucuronosyltransferase 1-2
Search

0.54	UDP-glucuronosyltransferase

0.61	GO:0052695	cellular glucuronidation
0.57	GO:0009812	flavonoid metabolic process
0.53	GO:0006805	xenobiotic metabolic process
0.47	GO:2001030	negative regulation of cellular glucuronidation
0.46	GO:1904223	regulation of glucuronosyltransferase activity
0.44	GO:0043086	negative regulation of catalytic activity
0.43	GO:0045922	negative regulation of fatty acid metabolic process
0.42	GO:0001889	liver development
0.42	GO:0042440	pigment metabolic process
0.41	GO:0031100	animal organ regeneration

0.81	GO:0015020	glucuronosyltransferase activity
0.51	GO:0001972	retinoic acid binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.47	GO:0019899	enzyme binding
0.45	GO:0005496	steroid binding
0.44	GO:0004857	enzyme inhibitor activity
0.41	GO:0005504	fatty acid binding
0.35	GO:0008144	drug binding
0.34	GO:0032403	protein complex binding

0.50	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0070062	extracellular exosome
0.37	GO:0043234	protein complex
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

0.81

GO:0015020

sp|P20759|IGHG1_RAT
Ig gamma-1 chain C region
Search

0.93	Immunoglobulin heavy constant mu

0.67	GO:0006910	phagocytosis, recognition
0.67	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.66	GO:0006911	phagocytosis, engulfment
0.65	GO:0050853	B cell receptor signaling pathway
0.64	GO:0006956	complement activation
0.64	GO:0050871	positive regulation of B cell activation
0.61	GO:0042742	defense response to bacterium
0.60	GO:0045087	innate immune response
0.52	GO:0002673	regulation of acute inflammatory response
0.50	GO:0002697	regulation of immune effector process

0.71	GO:0003823	antigen binding
0.68	GO:0034987	immunoglobulin receptor binding
0.40	GO:0004252	serine-type endopeptidase activity

0.68	GO:0042571	immunoglobulin complex, circulating
0.67	GO:0072562	blood microparticle
0.63	GO:0009897	external side of plasma membrane
0.48	GO:0070062	extracellular exosome
0.38	GO:0005771	multivesicular body
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.40

GO:0004252

sp|P20760|IGG2A_RAT
Ig gamma-2A chain C region
Search

0.93	Immunoglobulin heavy constant mu

0.66	GO:0006910	phagocytosis, recognition
0.66	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.66	GO:0006911	phagocytosis, engulfment
0.64	GO:0050853	B cell receptor signaling pathway
0.64	GO:0006956	complement activation
0.64	GO:0050871	positive regulation of B cell activation
0.61	GO:0042742	defense response to bacterium
0.60	GO:0045087	innate immune response
0.50	GO:0002673	regulation of acute inflammatory response
0.48	GO:0002697	regulation of immune effector process

0.71	GO:0003823	antigen binding
0.67	GO:0034987	immunoglobulin receptor binding
0.38	GO:0004252	serine-type endopeptidase activity

0.67	GO:0042571	immunoglobulin complex, circulating
0.67	GO:0072562	blood microparticle
0.63	GO:0009897	external side of plasma membrane
0.46	GO:0070062	extracellular exosome
0.39	GO:0005771	multivesicular body
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.38

GO:0004252

sp|P20761|IGG2B_RAT
Ig gamma-2B chain C region
Search

0.95	Immunoglobulin heavy constant mu

0.67	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.67	GO:0006910	phagocytosis, recognition
0.67	GO:0006911	phagocytosis, engulfment
0.66	GO:0050853	B cell receptor signaling pathway
0.65	GO:0050871	positive regulation of B cell activation
0.65	GO:0006956	complement activation
0.62	GO:0042742	defense response to bacterium
0.61	GO:0045087	innate immune response
0.51	GO:0002673	regulation of acute inflammatory response
0.49	GO:0002697	regulation of immune effector process

0.72	GO:0003823	antigen binding
0.69	GO:0034987	immunoglobulin receptor binding
0.40	GO:0004252	serine-type endopeptidase activity

0.68	GO:0042571	immunoglobulin complex, circulating
0.68	GO:0072562	blood microparticle
0.64	GO:0009897	external side of plasma membrane
0.46	GO:0070062	extracellular exosome
0.39	GO:0005771	multivesicular body
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.40

GO:0004252

sp|P20762|IGG2C_RAT
Ig gamma-2C chain C region
Search

0.94	Immunoglobulin heavy constant mu

0.66	GO:0006910	phagocytosis, recognition
0.66	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.65	GO:0006911	phagocytosis, engulfment
0.64	GO:0050853	B cell receptor signaling pathway
0.64	GO:0050871	positive regulation of B cell activation
0.64	GO:0006956	complement activation
0.61	GO:0042742	defense response to bacterium
0.60	GO:0045087	innate immune response
0.50	GO:0002673	regulation of acute inflammatory response
0.49	GO:0002697	regulation of immune effector process

0.71	GO:0003823	antigen binding
0.68	GO:0034987	immunoglobulin receptor binding
0.39	GO:0004252	serine-type endopeptidase activity

0.67	GO:0042571	immunoglobulin complex, circulating
0.66	GO:0072562	blood microparticle
0.62	GO:0009897	external side of plasma membrane
0.46	GO:0070062	extracellular exosome
0.38	GO:0005771	multivesicular body
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.39

GO:0004252

sp|P20766|LAC1_RAT
Ig lambda-1 chain C region
Search

0.97	Ig lambda chain C regions

0.77	GO:0006910	phagocytosis, recognition
0.76	GO:0006911	phagocytosis, engulfment
0.76	GO:0050853	B cell receptor signaling pathway
0.76	GO:0006958	complement activation, classical pathway
0.75	GO:0050871	positive regulation of B cell activation
0.70	GO:0045087	innate immune response
0.69	GO:0042742	defense response to bacterium
0.48	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.48	GO:0050900	leukocyte migration
0.48	GO:0038095	Fc-epsilon receptor signaling pathway

0.82	GO:0003823	antigen binding
0.78	GO:0034987	immunoglobulin receptor binding
0.42	GO:0004252	serine-type endopeptidase activity

0.78	GO:0072562	blood microparticle
0.77	GO:0042571	immunoglobulin complex, circulating
0.72	GO:0009897	external side of plasma membrane
0.50	GO:0070062	extracellular exosome
0.42	GO:0019815	B cell receptor complex

0.42

GO:0004252

sp|P20767|LAC2_RAT
Ig lambda-2 chain C region
Search

0.97	Ig lambda chain C regions

0.75	GO:0006910	phagocytosis, recognition
0.75	GO:0006911	phagocytosis, engulfment
0.74	GO:0002250	adaptive immune response
0.74	GO:0050853	B cell receptor signaling pathway
0.73	GO:0050871	positive regulation of B cell activation
0.73	GO:0002449	lymphocyte mediated immunity
0.72	GO:0006956	complement activation
0.68	GO:0045087	innate immune response
0.68	GO:0042742	defense response to bacterium
0.51	GO:0002377	immunoglobulin production

0.79	GO:0003823	antigen binding
0.76	GO:0034987	immunoglobulin receptor binding
0.40	GO:0004252	serine-type endopeptidase activity

0.76	GO:0072562	blood microparticle
0.75	GO:0042571	immunoglobulin complex, circulating
0.71	GO:0009897	external side of plasma membrane
0.50	GO:0070062	extracellular exosome

0.40

GO:0004252

sp|P20781|GLRB_RAT
Glycine receptor subunit beta
Search

GLRB

0.97	Glycine receptor subunit beta

0.77	GO:0060079	excitatory postsynaptic potential
0.74	GO:1902476	chloride transmembrane transport
0.61	GO:0060012	synaptic transmission, glycinergic
0.60	GO:0097112	gamma-aminobutyric acid receptor clustering
0.59	GO:0060013	righting reflex
0.58	GO:0001964	startle response
0.57	GO:0007628	adult walking behavior
0.57	GO:0007340	acrosome reaction
0.56	GO:0007218	neuropeptide signaling pathway
0.53	GO:0007601	visual perception

0.85	GO:0016934	extracellularly glycine-gated chloride channel activity
0.68	GO:0099600	transmembrane receptor activity
0.63	GO:0038023	signaling receptor activity
0.60	GO:0016594	glycine binding
0.35	GO:0005515	protein binding

0.77	GO:0045211	postsynaptic membrane
0.61	GO:0016935	glycine-gated chloride channel complex
0.60	GO:0098982	GABA-ergic synapse
0.39	GO:0030425	dendrite
0.38	GO:0030054	cell junction
0.35	GO:0043204	perikaryon
0.35	GO:0009897	external side of plasma membrane
0.34	GO:0005783	endoplasmic reticulum

sp|P20786|PGFRA_RAT
Platelet-derived growth factor receptor alpha
Search

PDGFRA

0.68	Platelet-derived growth factor receptor alpha

0.85	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.64	GO:0006935	chemotaxis
0.63	GO:0007275	multicellular organism development
0.59	GO:0023019	signal transduction involved in regulation of gene expression
0.58	GO:0008210	estrogen metabolic process
0.58	GO:0060325	face morphogenesis
0.57	GO:0022602	ovulation cycle process
0.57	GO:0060021	palate development
0.57	GO:1904888	cranial skeletal system development

0.85	GO:0005018	platelet-derived growth factor alpha-receptor activity
0.60	GO:0048407	platelet-derived growth factor binding
0.54	GO:0038085	vascular endothelial growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005161	platelet-derived growth factor receptor binding
0.52	GO:0032403	protein complex binding
0.51	GO:0005021	vascular endothelial growth factor-activated receptor activity

0.57	GO:0005902	microvillus
0.55	GO:0009897	external side of plasma membrane
0.46	GO:0030054	cell junction
0.46	GO:0005634	nucleus
0.44	GO:0031226	intrinsic component of plasma membrane
0.41	GO:0043234	protein complex
0.40	GO:0070013	intracellular organelle lumen
0.40	GO:0005737	cytoplasm
0.37	GO:0044446	intracellular organelle part
0.35	GO:0030424	axon

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P20788|UCRI_RAT
Cytochrome b-c1 complex subunit Rieske, mitochondrial
Search

UQCRFS1

0.69	Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

0.61	GO:0022900	electron transport chain
0.37	GO:0009725	response to hormone
0.37	GO:0046677	response to antibiotic
0.36	GO:0042493	response to drug
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.74	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.38	GO:0046872	metal ion binding
0.37	GO:0032403	protein complex binding

0.61	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.47	GO:0098798	mitochondrial protein complex
0.45	GO:0070069	cytochrome complex
0.45	GO:1990204	oxidoreductase complex
0.42	GO:0098796	membrane protein complex
0.41	GO:0043209	myelin sheath
0.30	GO:0016021	integral component of membrane

0.74

EC:1.10.2

GO:0016681

sp|P20789|NTR1_RAT
Neurotensin receptor type 1
Search

NTSR1

0.96	Neurotensin receptor type 1

0.77	GO:0007218	neuropeptide signaling pathway
0.60	GO:0008344	adult locomotory behavior
0.57	GO:0043066	negative regulation of apoptotic process
0.44	GO:0014054	positive regulation of gamma-aminobutyric acid secretion
0.44	GO:0097151	positive regulation of inhibitory postsynaptic potential
0.44	GO:0090238	positive regulation of arachidonic acid secretion
0.44	GO:0014049	positive regulation of glutamate secretion
0.44	GO:0070779	D-aspartate import
0.44	GO:0098712	L-glutamate import across plasma membrane
0.43	GO:0060732	positive regulation of inositol phosphate biosynthetic process

0.85	GO:0016492	G-protein coupled neurotensin receptor activity
0.54	GO:0042802	identical protein binding
0.48	GO:0016520	growth hormone-releasing hormone receptor activity
0.47	GO:0001607	neuromedin U receptor activity
0.42	GO:0047485	protein N-terminus binding
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0004997	thyrotropin-releasing hormone receptor activity

0.58	GO:0098857	membrane microdomain
0.50	GO:0005887	integral component of plasma membrane
0.44	GO:0032280	symmetric synapse
0.43	GO:0043198	dendritic shaft
0.42	GO:0043204	perikaryon
0.42	GO:0043195	terminal bouton
0.42	GO:0043197	dendritic spine
0.40	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0009986	cell surface
0.39	GO:0005794	Golgi apparatus

0.35

GO:0051353

sp|P20793|MAK_RAT
Serine/threonine-protein kinase MAK
Search

MAK

0.86	Male germ cell associated kinase

0.66	GO:0046777	protein autophosphorylation
0.56	GO:0042073	intraciliary transport
0.54	GO:0060271	cilium assembly
0.50	GO:0060255	regulation of macromolecule metabolic process
0.48	GO:0080090	regulation of primary metabolic process
0.48	GO:0031326	regulation of cellular biosynthetic process
0.48	GO:0051171	regulation of nitrogen compound metabolic process
0.46	GO:0035556	intracellular signal transduction

0.64	GO:0003713	transcription coactivator activity
0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0001917	photoreceptor inner segment
0.67	GO:0030496	midbody
0.66	GO:0072686	mitotic spindle
0.64	GO:0005813	centrosome
0.53	GO:0005634	nucleus
0.52	GO:0005929	cilium
0.39	GO:0005737	cytoplasm

sp|P20812|CP2A3_RAT
Cytochrome P450 2A3
Search

0.97	Felis catus cytochrome P450, family 2, subfamily A, polypeptide 13

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0019373	epoxygenase P450 pathway

0.77	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0008392	arachidonic acid epoxygenase activity
0.45	GO:0008395	steroid hydroxylase activity

0.77

GO:0016712

sp|P20814|CP2CD_RAT
Cytochrome P450 2C13, male-specific
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.59	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0042738	exogenous drug catabolic process
0.44	GO:0043651	linoleic acid metabolic process
0.43	GO:0008202	steroid metabolic process
0.43	GO:0016098	monoterpenoid metabolic process
0.43	GO:0070988	demethylation
0.43	GO:0002933	lipid hydroxylation
0.37	GO:0019627	urea metabolic process
0.37	GO:0006805	xenobiotic metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.48	GO:0034875	caffeine oxidase activity
0.38	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding

0.47	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P20816|CP4A2_RAT
Cytochrome P450 4A2
Search

0.97	Fatty acid omega-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0006690	icosanoid metabolic process
0.44	GO:0033559	unsaturated fatty acid metabolic process
0.43	GO:0001676	long-chain fatty acid metabolic process
0.42	GO:0048252	lauric acid metabolic process
0.40	GO:1901569	fatty acid derivative catabolic process
0.39	GO:0001822	kidney development
0.39	GO:0009062	fatty acid catabolic process
0.39	GO:1901616	organic hydroxy compound catabolic process
0.38	GO:1901570	fatty acid derivative biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0103002	16-hydroxypalmitate dehydrogenase activity
0.36	GO:0050544	arachidonic acid binding
0.34	GO:0019825	oxygen binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0016324	apical plasma membrane
0.39	GO:0031090	organelle membrane
0.39	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P20817|CP4AE_RAT
Cytochrome P450 4A14
Search

0.97	Fatty acid omega-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0006690	icosanoid metabolic process
0.44	GO:0033559	unsaturated fatty acid metabolic process
0.43	GO:0001676	long-chain fatty acid metabolic process
0.42	GO:0048252	lauric acid metabolic process
0.41	GO:1901569	fatty acid derivative catabolic process
0.39	GO:0009062	fatty acid catabolic process
0.39	GO:0001822	kidney development
0.39	GO:1901616	organic hydroxy compound catabolic process
0.38	GO:1901570	fatty acid derivative biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0103002	16-hydroxypalmitate dehydrogenase activity
0.36	GO:0050544	arachidonic acid binding
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0016324	apical plasma membrane
0.39	GO:0031090	organelle membrane
0.39	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P20850|CO9A1_RAT
Collagen alpha-1(IX) chain (Fragment)
Search

COL9A1

0.75	Collagen alpha-1(IX) chain

0.45	GO:0061304	retinal blood vessel morphogenesis
0.44	GO:0071711	basement membrane organization
0.44	GO:0009888	tissue development
0.43	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.43	GO:0007528	neuromuscular junction development
0.43	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0001763	morphogenesis of a branching structure
0.42	GO:0072001	renal system development
0.42	GO:0001525	angiogenesis
0.42	GO:0035239	tube morphogenesis

0.51	GO:0005201	extracellular matrix structural constituent
0.44	GO:0048407	platelet-derived growth factor binding
0.35	GO:0042302	structural constituent of cuticle
0.35	GO:0046872	metal ion binding
0.35	GO:0097493	structural molecule activity conferring elasticity

0.76	GO:0005581	collagen trimer
0.48	GO:0005578	proteinaceous extracellular matrix
0.47	GO:0044420	extracellular matrix component
0.40	GO:0005615	extracellular space
0.40	GO:0099081	supramolecular polymer
0.38	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P20909|COBA1_RAT
Collagen alpha-1(XI) chain
Search

0.73	Collagen, type XI, alpha 1a

0.81

GO:0005201

extracellular matrix structural constituent

0.52	GO:0005581	collagen trimer
0.30	GO:0044425	membrane part

sp|P20942|PHOS_RAT
Phosducin
Search

PDC

0.72	Phosducin b

0.57	GO:0008616	queuosine biosynthetic process
0.52	GO:0007601	visual perception
0.42	GO:0050896	response to stimulus
0.38	GO:0019371	cyclooxygenase pathway
0.37	GO:0043086	negative regulation of catalytic activity
0.37	GO:0008217	regulation of blood pressure
0.35	GO:0023052	signaling
0.35	GO:0007154	cell communication
0.34	GO:0050789	regulation of biological process
0.33	GO:0055114	oxidation-reduction process

0.61	GO:0008479	queuine tRNA-ribosyltransferase activity
0.40	GO:0004859	phospholipase inhibitor activity
0.38	GO:0004666	prostaglandin-endoperoxide synthase activity
0.36	GO:0004601	peroxidase activity
0.35	GO:0020037	heme binding

0.83	GO:0001750	photoreceptor outer segment
0.55	GO:0001917	photoreceptor inner segment
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus

0.61	EC:2.4.2.29	GO:0008479
0.36	KEGG:R03532	GO:0004601

sp|P20961|PAI1_RAT
Plasminogen activator inhibitor 1
Search

SERPINE1

0.94	Clade E serpine peptidase inhibitor

0.67	GO:0010757	negative regulation of plasminogen activation
0.64	GO:1901331	positive regulation of odontoblast differentiation
0.64	GO:0035490	regulation of leukotriene production involved in inflammatory response
0.64	GO:0061044	negative regulation of vascular wound healing
0.63	GO:0097187	dentinogenesis
0.63	GO:2000098	negative regulation of smooth muscle cell-matrix adhesion
0.62	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.62	GO:0030193	regulation of blood coagulation
0.61	GO:0090399	replicative senescence
0.61	GO:0014912	negative regulation of smooth muscle cell migration

0.61	GO:0004867	serine-type endopeptidase inhibitor activity
0.58	GO:0002020	protease binding
0.55	GO:0005102	receptor binding
0.44	GO:0008201	heparin binding
0.36	GO:0035375	zymogen binding
0.33	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.32	GO:0008233	peptidase activity
0.32	GO:0046872	metal ion binding

0.73	GO:0005615	extracellular space
0.57	GO:1903561	extracellular vesicle
0.56	GO:0031012	extracellular matrix
0.47	GO:0031232	extrinsic component of external side of plasma membrane
0.47	GO:0031091	platelet alpha granule
0.45	GO:0031594	neuromuscular junction
0.41	GO:0005829	cytosol
0.37	GO:0042583	chromaffin granule
0.36	GO:0034774	secretory granule lumen
0.34	GO:0030117	membrane coat

0.32

GO:0008233

sp|P21139|MA2C1_RAT
Alpha-mannosidase 2C1
Search

MAN2C1

0.47	Alpha-mannosidase

0.80	GO:0006013	mannose metabolic process
0.48	GO:0006517	protein deglycosylation
0.35	GO:0009313	oligosaccharide catabolic process
0.34	GO:1903507	negative regulation of nucleic acid-templated transcription
0.32	GO:0006355	regulation of transcription, DNA-templated

0.79	GO:0004559	alpha-mannosidase activity
0.69	GO:0030246	carbohydrate binding
0.48	GO:0046872	metal ion binding
0.34	GO:0003714	transcription corepressor activity

0.48	GO:0005654	nucleoplasm
0.44	GO:0005773	vacuole
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005829	cytosol
0.34	GO:0000790	nuclear chromatin
0.33	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.2.1.24

GO:0004559

sp|P21213|HUTH_RAT
Histidine ammonia-lyase
Search

HAL

0.58	Histidine ammonia-lyase

0.76	GO:0019557	histidine catabolic process to glutamate and formate
0.76	GO:0043606	formamide metabolic process
0.45	GO:0060218	hematopoietic stem cell differentiation

0.80

GO:0004397

histidine ammonia-lyase activity

0.48

GO:0005737

cytoplasm

0.80

EC:4.3.1.3

GO:0004397

sp|P21263|NEST_RAT
Nestin
Search

NES

0.85

Nestin

0.65	GO:0000086	G2/M transition of mitotic cell cycle
0.65	GO:0072089	stem cell proliferation
0.64	GO:0032091	negative regulation of protein binding
0.56	GO:0043086	negative regulation of catalytic activity
0.48	GO:0030842	regulation of intermediate filament depolymerization
0.45	GO:2000179	positive regulation of neural precursor cell proliferation
0.45	GO:0031076	embryonic camera-type eye development
0.45	GO:1901881	positive regulation of protein depolymerization
0.43	GO:0007420	brain development
0.43	GO:0051495	positive regulation of cytoskeleton organization

0.86	GO:0019215	intermediate filament binding
0.62	GO:0005198	structural molecule activity
0.37	GO:0008289	lipid binding
0.30	GO:0005102	receptor binding

0.79	GO:0005882	intermediate filament
0.42	GO:0005737	cytoplasm
0.39	GO:0031012	extracellular matrix

sp|P21272|CEBPB_RAT
CCAAT/enhancer-binding protein beta
Search

CEBPB

0.92	CCAAT enhancer binding protein beta

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0001889	liver development
0.56	GO:0045600	positive regulation of fat cell differentiation
0.55	GO:0045669	positive regulation of osteoblast differentiation
0.55	GO:0045444	fat cell differentiation
0.53	GO:0001892	embryonic placenta development
0.53	GO:0009617	response to bacterium
0.52	GO:0008285	negative regulation of cell proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0035035	histone acetyltransferase binding
0.51	GO:0019900	kinase binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0042826	histone deacetylase binding
0.50	GO:0001047	core promoter binding
0.48	GO:0044389	ubiquitin-like protein ligase binding
0.47	GO:0003682	chromatin binding

0.50	GO:0016363	nuclear matrix
0.50	GO:0005654	nucleoplasm
0.48	GO:0000779	condensed chromosome, centromeric region
0.47	GO:0000790	nuclear chromatin
0.46	GO:0090575	RNA polymerase II transcription factor complex
0.37	GO:0005737	cytoplasm
0.35	GO:0005730	nucleolus
0.32	GO:0005886	plasma membrane

sp|P21396|AOFA_RAT
Amine oxidase [flavin-containing] A
Search

MAOA

0.48	Amine oxidase [flavin-containing] A

0.55	GO:0042420	dopamine catabolic process
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0042135	neurotransmitter catabolic process
0.36	GO:0042443	phenylethylamine metabolic process
0.35	GO:0042428	serotonin metabolic process
0.35	GO:0014063	negative regulation of serotonin secretion
0.35	GO:0010269	response to selenium ion
0.35	GO:0021762	substantia nigra development
0.35	GO:0045915	positive regulation of catecholamine metabolic process
0.35	GO:0051412	response to corticosterone

0.54	GO:0016491	oxidoreductase activity
0.35	GO:0051378	serotonin binding
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0005515	protein binding

0.46	GO:0005739	mitochondrion
0.43	GO:0031968	organelle outer membrane
0.40	GO:0019866	organelle inner membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.54

GO:0016491

sp|P21451|EDNRB_RAT
Endothelin B receptor
Search

EDNRB

0.96	Endothelin receptor type B

0.83	GO:0086100	endothelin receptor signaling pathway
0.82	GO:0048484	enteric nervous system development
0.80	GO:0042310	vasoconstriction
0.77	GO:0008217	regulation of blood pressure
0.61	GO:0035645	enteric smooth muscle cell differentiation
0.61	GO:0007497	posterior midgut development
0.60	GO:0014043	negative regulation of neuron maturation
0.59	GO:0050931	pigment cell differentiation
0.59	GO:0048246	macrophage chemotaxis
0.59	GO:0014821	phasic smooth muscle contraction

0.83	GO:0004962	endothelin receptor activity
0.58	GO:0017046	peptide hormone binding
0.42	GO:0031702	type 1 angiotensin receptor binding

0.43	GO:0005886	plasma membrane
0.39	GO:0098857	membrane microdomain
0.39	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

sp|P21463|TSHR_RAT
Thyrotropin receptor
Search

TSHR

0.95	Thyrotropin receptor

0.86	GO:0038194	thyroid-stimulating hormone signaling pathway
0.59	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.57	GO:0090103	cochlea morphogenesis
0.57	GO:0071542	dopaminergic neuron differentiation
0.56	GO:0060122	inner ear receptor cell stereocilium organization
0.56	GO:0040018	positive regulation of multicellular organism growth
0.55	GO:0030183	B cell differentiation
0.55	GO:0008344	adult locomotory behavior
0.52	GO:0040012	regulation of locomotion
0.52	GO:0007190	activation of adenylate cyclase activity

0.86	GO:0004996	thyroid-stimulating hormone receptor activity
0.48	GO:0008528	G-protein coupled peptide receptor activity
0.42	GO:0032403	protein complex binding

0.54	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.38	GO:0043235	receptor complex
0.35	GO:0045121	membrane raft
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P21531|RL3_RAT
60S ribosomal protein L3
Search

RPL3

0.61	Ribosomal protein L3

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.50	GO:0071353	cellular response to interleukin-4
0.46	GO:0031017	exocrine pancreas development
0.43	GO:0000027	ribosomal large subunit assembly
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.62	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.60	GO:0005840	ribosome
0.47	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.32

GO:0016787

sp|P21533|RL6_RAT
60S ribosomal protein L6
Search

RPL6

0.71	LOW QUALITY PROTEIN: 60S ribosomal protein L6

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.45	GO:0000027	ribosomal large subunit assembly
0.37	GO:0031016	pancreas development
0.36	GO:0043009	chordate embryonic development
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.45	GO:0045296	cadherin binding
0.40	GO:0003723	RNA binding
0.33	GO:0003677	DNA binding
0.33	GO:0009982	pseudouridine synthase activity
0.33	GO:0016874	ligase activity

0.60	GO:0005840	ribosome
0.47	GO:0005844	polysome
0.47	GO:0044445	cytosolic part
0.44	GO:0036464	cytoplasmic ribonucleoprotein granule
0.41	GO:0044446	intracellular organelle part
0.39	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.35	GO:0031672	A band
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane

0.33

EC:5.4.99.12

GO:0009982

sp|P21555|NPY1R_RAT
Neuropeptide Y receptor type 1
Search

NPY1R

0.97	Neuropeptide Y receptor type 1

0.79	GO:0007218	neuropeptide signaling pathway
0.58	GO:0007631	feeding behavior
0.58	GO:0003151	outflow tract morphogenesis
0.57	GO:0019233	sensory perception of pain
0.56	GO:0040014	regulation of multicellular organism growth
0.56	GO:0008015	blood circulation
0.55	GO:0007626	locomotory behavior
0.50	GO:0006006	glucose metabolic process
0.46	GO:0007268	chemical synaptic transmission
0.46	GO:0065008	regulation of biological quality

0.83	GO:0004983	neuropeptide Y receptor activity
0.44	GO:0042923	neuropeptide binding
0.34	GO:0017046	peptide hormone binding
0.33	GO:0005515	protein binding

0.37	GO:0005886	plasma membrane
0.35	GO:0008021	synaptic vesicle
0.35	GO:0030424	axon
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P21571|ATP5J_RAT
ATP synthase-coupling factor 6, mitochondrial
Search

ATP5J

0.95	ATP synthase-coupling factor 6, mitochondrial

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0021762	substantia nigra development
0.35	GO:0042407	cristae formation
0.34	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.43	GO:0016887	ATPase activity
0.36	GO:0047624	adenosine-tetraphosphatase activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.43

GO:0016887

sp|P21575|DYN1_RAT
Dynamin-1
Search

DNM1

0.94	Dynamin 1 short form

0.73	GO:0072583	clathrin-dependent endocytosis
0.54	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane
0.53	GO:0051932	synaptic transmission, GABAergic
0.51	GO:0007032	endosome organization
0.50	GO:0008344	adult locomotory behavior
0.49	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.49	GO:0007605	sensory perception of sound
0.49	GO:1901998	toxin transport
0.49	GO:0051262	protein tetramerization
0.47	GO:0000266	mitochondrial fission

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0042802	identical protein binding
0.44	GO:0046983	protein dimerization activity
0.44	GO:0008017	microtubule binding
0.40	GO:0031749	D2 dopamine receptor binding
0.39	GO:0050998	nitric-oxide synthase binding
0.39	GO:0008022	protein C-terminus binding
0.36	GO:0032403	protein complex binding

0.51	GO:0001917	photoreceptor inner segment
0.50	GO:0043209	myelin sheath
0.47	GO:0045202	synapse
0.47	GO:0030117	membrane coat
0.46	GO:0005654	nucleoplasm
0.40	GO:0031966	mitochondrial membrane
0.39	GO:0043196	varicosity
0.38	GO:0099503	secretory vesicle
0.37	GO:0005874	microtubule
0.37	GO:0030133	transport vesicle

sp|P21581|SCF_RAT
Kit ligand
Search

KITLG

0.97	Kit ligand

0.71	GO:0007155	cell adhesion
0.65	GO:0010469	regulation of receptor activity
0.63	GO:0033026	negative regulation of mast cell apoptotic process
0.63	GO:0070668	positive regulation of mast cell proliferation
0.62	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.62	GO:0045636	positive regulation of melanocyte differentiation
0.61	GO:0035162	embryonic hemopoiesis
0.61	GO:0035234	ectopic germ cell programmed cell death
0.61	GO:0045740	positive regulation of DNA replication
0.60	GO:0008584	male gonad development

0.86	GO:0005173	stem cell factor receptor binding
0.66	GO:0008083	growth factor activity
0.56	GO:0005125	cytokine activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.63	GO:0030175	filopodium
0.62	GO:0030027	lamellipodium
0.52	GO:0005615	extracellular space
0.50	GO:0005886	plasma membrane
0.44	GO:0005856	cytoskeleton
0.41	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|P21588|5NTD_RAT
5'-nucleotidase
Search

NT5E

0.49	Snake venom 5'-nucleotidase

0.75	GO:0009166	nucleotide catabolic process
0.59	GO:0046086	adenosine biosynthetic process
0.57	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.57	GO:0007159	leukocyte cell-cell adhesion
0.56	GO:0050728	negative regulation of inflammatory response
0.52	GO:0072523	purine-containing compound catabolic process
0.51	GO:0046033	AMP metabolic process
0.50	GO:0016311	dephosphorylation
0.49	GO:0042737	drug catabolic process
0.49	GO:1901136	carbohydrate derivative catabolic process

0.59	GO:0016788	hydrolase activity, acting on ester bonds
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0046872	metal ion binding
0.51	GO:0036094	small molecule binding

0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.41	GO:0031225	anchored component of membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0009986	cell surface
0.35	GO:0044456	synapse part
0.30	GO:0016021	integral component of membrane

0.59

EC:3.1

GO:0016788

sp|P21643|T23O_RAT
Tryptophan 2,3-dioxygenase
Search

TDO2

0.63	Tryptophan 2,3-dioxygenase A

0.78	GO:0019441	tryptophan catabolic process to kynurenine
0.59	GO:0051289	protein homotetramerization
0.54	GO:0019442	tryptophan catabolic process to acetyl-CoA
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0033060	ocellus pigmentation
0.49	GO:0006726	eye pigment biosynthetic process
0.44	GO:0044550	secondary metabolite biosynthetic process
0.38	GO:0018130	heterocycle biosynthetic process
0.38	GO:1901362	organic cyclic compound biosynthetic process
0.38	GO:0019438	aromatic compound biosynthetic process

0.83	GO:0004833	tryptophan 2,3-dioxygenase activity
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.52	GO:0042802	identical protein binding
0.39	GO:0019825	oxygen binding
0.38	GO:0016597	amino acid binding
0.35	GO:0008234	cysteine-type peptidase activity

0.34

GO:0005829

cytosol

0.83

EC:1.13.11.11

GO:0004833

sp|P21670|PSA4_RAT
Proteasome subunit alpha type-4
Search

PSMA4

0.49	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.71	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0010608	posttranscriptional regulation of gene expression
0.36	GO:0032269	negative regulation of cellular protein metabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0034249	negative regulation of cellular amide metabolic process
0.35	GO:0006879	cellular iron ion homeostasis
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway

0.77	GO:0004298	threonine-type endopeptidase activity
0.37	GO:0030350	iron-responsive element binding
0.36	GO:0030371	translation repressor activity
0.33	GO:0005515	protein binding
0.32	GO:0016301	kinase activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.60	GO:0005634	nucleus
0.51	GO:0000932	P-body
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.77

GO:0004298

sp|P21674|FST_RAT
Follistatin
Search

FST

0.97	Follistatin

0.85	GO:0032926	negative regulation of activin receptor signaling pathway
0.84	GO:0051798	positive regulation of hair follicle development
0.80	GO:0002244	hematopoietic progenitor cell differentiation
0.73	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0043616	keratinocyte proliferation
0.44	GO:0031069	hair follicle morphogenesis
0.44	GO:0045596	negative regulation of cell differentiation
0.44	GO:0001501	skeletal system development
0.43	GO:0007389	pattern specification process
0.43	GO:0042475	odontogenesis of dentin-containing tooth

0.85	GO:0048185	activin binding
0.49	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.36	GO:0004871	signal transducer activity

0.49	GO:0005576	extracellular region
0.37	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

0.36

EC:1.6

GO:0016651

sp|P21677|TFE2_RAT
Transcription factor E2-alpha
Search

TCF3

0.94	Transcription factor 3 variant 3

0.59	GO:0033152	immunoglobulin V(D)J recombination
0.54	GO:0051091	positive regulation of DNA binding transcription factor activity
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0045666	positive regulation of neuron differentiation
0.43	GO:0002326	B cell lineage commitment
0.43	GO:0006351	transcription, DNA-templated
0.42	GO:0030890	positive regulation of B cell proliferation
0.41	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.40	GO:0045787	positive regulation of cell cycle

0.68	GO:0046983	protein dimerization activity
0.58	GO:0070644	vitamin D response element binding
0.58	GO:0043425	bHLH transcription factor binding
0.57	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.56	GO:0070888	E-box binding
0.55	GO:0070491	repressing transcription factor binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0003713	transcription coactivator activity
0.51	GO:0042802	identical protein binding
0.40	GO:0035326	enhancer binding

0.52	GO:0005667	transcription factor complex
0.52	GO:0016607	nuclear speck
0.50	GO:0000790	nuclear chromatin
0.39	GO:0005737	cytoplasm
0.37	GO:0000786	nucleosome

sp|P21702|PR3D1_RAT
Prolactin-3D1
Search

0.97	Placental lactogen I mosaic

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0042976	activation of Janus kinase activity
0.41	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.39	GO:0016525	negative regulation of angiogenesis

0.79	GO:0005179	hormone activity
0.44	GO:0005148	prolactin receptor binding
0.38	GO:0005125	cytokine activity

0.66

GO:0005576

extracellular region

sp|P21704|DNAS1_RAT
Deoxyribonuclease-1
Search

DNASE1

0.63	Deoxyribonuclease

0.76	GO:0006308	DNA catabolic process
0.60	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.58	GO:0002283	neutrophil activation involved in immune response
0.58	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0002673	regulation of acute inflammatory response
0.48	GO:0003335	corneocyte development
0.45	GO:0001942	hair follicle development
0.43	GO:0006915	apoptotic process
0.35	GO:0010623	programmed cell death involved in cell development
0.34	GO:0022411	cellular component disassembly

0.71	GO:0004536	deoxyribonuclease activity
0.60	GO:0004519	endonuclease activity
0.42	GO:0003779	actin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.42	GO:0005635	nuclear envelope
0.40	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

sp|P21707|SYT1_RAT
Synaptotagmin-1
Search

SYT1

0.88	Synaptotagmin Ia

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.75	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.62	GO:1903861	positive regulation of dendrite extension
0.59	GO:0017158	regulation of calcium ion-dependent exocytosis
0.57	GO:0017156	calcium ion regulated exocytosis
0.56	GO:0097479	synaptic vesicle localization
0.56	GO:0099003	vesicle-mediated transport in synapse

0.81	GO:0005544	calcium-dependent phospholipid binding
0.57	GO:0050750	low-density lipoprotein particle receptor binding
0.56	GO:0019905	syntaxin binding
0.55	GO:0048306	calcium-dependent protein binding
0.50	GO:0005509	calcium ion binding
0.49	GO:0030276	clathrin binding
0.47	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.41	GO:0001786	phosphatidylserine binding
0.40	GO:0005516	calmodulin binding
0.40	GO:0008022	protein C-terminus binding

0.81	GO:0008021	synaptic vesicle
0.59	GO:0099501	exocytic vesicle membrane
0.57	GO:0031045	dense core granule
0.55	GO:0042734	presynaptic membrane
0.52	GO:0030424	axon
0.48	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.45	GO:0042584	chromaffin granule membrane
0.41	GO:0030054	cell junction
0.40	GO:0060076	excitatory synapse

sp|P21708|MK03_RAT
Mitogen-activated protein kinase 3
Search

MAPK3

0.57	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.59	GO:0060440	trachea formation
0.59	GO:0042473	outer ear morphogenesis
0.59	GO:1903351	cellular response to dopamine
0.59	GO:0061308	cardiac neural crest cell development involved in heart development
0.59	GO:0060020	Bergmann glial cell differentiation
0.58	GO:1904355	positive regulation of telomere capping
0.58	GO:0070849	response to epidermal growth factor
0.58	GO:0030878	thyroid gland development
0.57	GO:0051973	positive regulation of telomerase activity

0.81	GO:0004707	MAP kinase activity
0.58	GO:0004708	MAP kinase kinase activity
0.57	GO:0001784	phosphotyrosine residue binding
0.55	GO:0019902	phosphatase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042802	identical protein binding
0.45	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity

0.58	GO:0031143	pseudopodium
0.50	GO:0005829	cytosol
0.50	GO:0005901	caveola
0.49	GO:0005925	focal adhesion
0.48	GO:0005770	late endosome
0.48	GO:0005769	early endosome
0.48	GO:0005635	nuclear envelope
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005856	cytoskeleton
0.43	GO:0005739	mitochondrion

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P21743|IBP1_RAT
Insulin-like growth factor-binding protein 1
Search

IGFBP1

0.93	Insulin like growth factor binding protein 1

0.76	GO:0001558	regulation of cell growth
0.51	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.43	GO:0031099	regeneration
0.41	GO:0008286	insulin receptor signaling pathway
0.40	GO:0045927	positive regulation of growth
0.40	GO:0007568	aging
0.40	GO:0042060	wound healing
0.40	GO:0048589	developmental growth
0.39	GO:0009888	tissue development
0.39	GO:0001666	response to hypoxia

0.84	GO:0005520	insulin-like growth factor binding
0.34	GO:0005102	receptor binding

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|P21744|IBP4_RAT
Insulin-like growth factor-binding protein 4
Search

IGFBP4

0.97	Insulin like growth factor binding protein 4

0.77	GO:0001558	regulation of cell growth
0.62	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.61	GO:0044342	type B pancreatic cell proliferation
0.57	GO:0010906	regulation of glucose metabolic process
0.55	GO:0043410	positive regulation of MAPK cascade
0.42	GO:0042127	regulation of cell proliferation
0.40	GO:0014912	negative regulation of smooth muscle cell migration
0.40	GO:0045663	positive regulation of myoblast differentiation
0.40	GO:0006954	inflammatory response
0.39	GO:0032868	response to insulin

0.84	GO:0005520	insulin-like growth factor binding
0.41	GO:0008160	protein tyrosine phosphatase activator activity
0.39	GO:0001968	fibronectin binding
0.35	GO:0005102	receptor binding

0.66	GO:0005576	extracellular region
0.41	GO:0036454	growth factor complex
0.36	GO:0005634	nucleus
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0031091	platelet alpha granule
0.33	GO:0000792	heterochromatin
0.32	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P21769|ODFP1_RAT
Outer dense fiber protein 1
Search

ODF1

0.97	LOW QUALITY PROTEIN: outer dense fiber protein 1

0.48	GO:0007283	spermatogenesis
0.45	GO:0030154	cell differentiation
0.44	GO:0048856	anatomical structure development
0.38	GO:0097722	sperm motility
0.37	GO:0035082	axoneme assembly
0.37	GO:0022412	cellular process involved in reproduction in multicellular organism
0.37	GO:0003006	developmental process involved in reproduction
0.36	GO:0001558	regulation of cell growth
0.33	GO:0007018	microtubule-based movement
0.33	GO:0022900	electron transport chain

0.42	GO:0019904	protein domain specific binding
0.37	GO:0005520	insulin-like growth factor binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0020037	heme binding
0.33	GO:0009055	electron transfer activity
0.32	GO:0004601	peroxidase activity
0.32	GO:0042803	protein homodimerization activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032550	purine ribonucleoside binding

0.86	GO:0001520	outer dense fiber
0.37	GO:0005634	nucleus
0.35	GO:0005882	intermediate filament
0.35	GO:0005576	extracellular region
0.34	GO:0005581	collagen trimer
0.33	GO:0097227	sperm annulus
0.33	GO:0031105	septin complex
0.33	GO:0030496	midbody
0.32	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005819	spindle

0.32	EC:1.11.1.7	GO:0004601
0.32	KEGG:R03532	GO:0004601

sp|P21775|THIKA_RAT
3-ketoacyl-CoA thiolase A, peroxisomal
Search

ACAA1

0.84	Acetyl-Coenzyme A acyltransferase 1

0.70	GO:0008206	bile acid metabolic process
0.67	GO:0000038	very long-chain fatty acid metabolic process
0.62	GO:0006635	fatty acid beta-oxidation

0.75	GO:0016401	palmitoyl-CoA oxidase activity
0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.62

GO:0042579

microbody

0.75

EC:1.3.3

GO:0016401

sp|P21794|HIP70_RAT
Hormone-induced protein 70 kDa (Fragment)
Search

0.44	Hormone-induced protein 70 kDa (Fragment)

sp|P21807|PERI_RAT
Peripherin
Search

PRPH

0.92	Muscle-specific intermediate filament desmin (Predicted)

0.53	GO:0045104	intermediate filament cytoskeleton organization
0.48	GO:0097435	supramolecular fiber organization
0.47	GO:0060020	Bergmann glial cell differentiation
0.47	GO:0032967	positive regulation of collagen biosynthetic process
0.47	GO:0070307	lens fiber cell development
0.46	GO:0014002	astrocyte development
0.46	GO:0060395	SMAD protein signal transduction
0.45	GO:0071346	cellular response to interferon-gamma
0.45	GO:0043488	regulation of mRNA stability
0.45	GO:0010977	negative regulation of neuron projection development

0.62	GO:0005198	structural molecule activity
0.48	GO:1990254	keratin filament binding
0.47	GO:0042802	identical protein binding
0.46	GO:0097110	scaffold protein binding
0.45	GO:0008022	protein C-terminus binding
0.43	GO:0019904	protein domain specific binding
0.43	GO:0003725	double-stranded RNA binding
0.41	GO:0008092	cytoskeletal protein binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0051721	protein phosphatase 2A binding

0.79	GO:0005882	intermediate filament
0.47	GO:0005916	fascia adherens
0.46	GO:0030018	Z disc
0.46	GO:0097512	cardiac myofibril
0.45	GO:0042383	sarcolemma
0.45	GO:0031594	neuromuscular junction
0.45	GO:0005844	polysome
0.45	GO:0045335	phagocytic vesicle
0.44	GO:0043005	neuron projection
0.44	GO:0031252	cell leading edge

sp|P21816|CDO1_RAT
Cysteine dioxygenase type 1
Search

CDO1

0.58	Cysteine dioxygenase type I

0.51	GO:0055114	oxidation-reduction process
0.44	GO:0046305	alkanesulfonate biosynthetic process
0.42	GO:0019530	taurine metabolic process
0.40	GO:0019448	L-cysteine catabolic process
0.39	GO:0033762	response to glucagon
0.39	GO:0007595	lactation
0.39	GO:0051591	response to cAMP
0.39	GO:0051384	response to glucocorticoid
0.39	GO:0045471	response to ethanol
0.39	GO:0043200	response to amino acid

0.72	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.61	GO:0005506	iron ion binding

0.47	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

0.72

EC:1.13.11

GO:0016702

sp|P21818|STMN2_RAT
Stathmin-2
Search

STMN2

0.85

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.60	GO:0048699	generation of neurons
0.56	GO:0120036	plasma membrane bounded cell projection organization
0.56	GO:0031122	cytoplasmic microtubule organization
0.55	GO:0048468	cell development
0.54	GO:1990090	cellular response to nerve growth factor stimulus
0.52	GO:1901881	positive regulation of protein depolymerization
0.51	GO:0031346	positive regulation of cell projection organization
0.51	GO:0032272	negative regulation of protein polymerization
0.51	GO:0031345	negative regulation of cell projection organization

0.54	GO:0015631	tubulin binding
0.52	GO:0048306	calcium-dependent protein binding
0.38	GO:0019904	protein domain specific binding

0.53	GO:0030426	growth cone
0.51	GO:0030027	lamellipodium
0.51	GO:0043025	neuronal cell body
0.49	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0030424	axon
0.37	GO:0031982	vesicle
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|P21913|SDHB_RAT
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Search

SDHB

0.69	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

0.69	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.37	GO:0006105	succinate metabolic process
0.34	GO:0018101	protein citrullination

0.77	GO:0051538	3 iron, 4 sulfur cluster binding
0.77	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.69	GO:0051537	2 iron, 2 sulfur cluster binding
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.61	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding
0.43	GO:0048039	ubiquinone binding
0.34	GO:0004668	protein-arginine deiminase activity
0.34	GO:0005515	protein binding

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.53	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.53	GO:0045283	fumarate reductase complex
0.48	GO:0098798	mitochondrial protein complex
0.45	GO:0005654	nucleoplasm
0.40	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome

0.77	EC:1.3.5.1	GO:0008177
0.77	KEGG:R02164	GO:0008177

sp|P21932|ADCY3_RAT
Adenylate cyclase type 3
Search

ADCY3

0.94	Adenylate cyclase type 3

0.76	GO:0006171	cAMP biosynthetic process
0.65	GO:1904321	response to forskolin
0.64	GO:0008355	olfactory learning
0.63	GO:0007340	acrosome reaction
0.62	GO:0035556	intracellular signal transduction
0.62	GO:0030317	flagellated sperm motility
0.62	GO:1901655	cellular response to ketone
0.60	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.59	GO:0035690	cellular response to drug
0.57	GO:0071396	cellular response to lipid

0.76	GO:0004016	adenylate cyclase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0004383	guanylate cyclase activity
0.40	GO:0005516	calmodulin binding
0.38	GO:0004045	aminoacyl-tRNA hydrolase activity
0.35	GO:0046872	metal ion binding

0.57	GO:0005929	cilium
0.54	GO:0005886	plasma membrane
0.51	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005794	Golgi apparatus
0.36	GO:0045121	membrane raft
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.76

GO:0004016

sp|P21961|CBPA3_RAT
Mast cell carboxypeptidase A (Fragment)
Search

CPA3

0.79	Pancreatic carboxypeptidase B

0.61	GO:0006508	proteolysis
0.56	GO:0002002	regulation of angiotensin levels in blood
0.45	GO:0042730	fibrinolysis
0.34	GO:0042445	hormone metabolic process
0.34	GO:0051604	protein maturation
0.33	GO:0007596	blood coagulation
0.33	GO:0006518	peptide metabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.32	GO:0003779	actin binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.52	GO:0044421	extracellular region part
0.37	GO:0030133	transport vesicle
0.35	GO:0030141	secretory granule
0.33	GO:0046658	anchored component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

GO:0004181

sp|P21994|CXB2_RAT
Gap junction beta-2 protein
Search

GJB2

0.63	Gap junction protein (Fragment)

0.60	GO:0007154	cell communication
0.57	GO:0016264	gap junction assembly
0.53	GO:0007605	sensory perception of sound
0.52	GO:0043583	ear development
0.49	GO:0048562	embryonic organ morphogenesis
0.49	GO:0090596	sensory organ morphogenesis
0.43	GO:0023052	signaling
0.43	GO:0032496	response to lipopolysaccharide
0.43	GO:0007568	aging
0.42	GO:1905867	epididymis development

0.57	GO:0005243	gap junction channel activity
0.49	GO:0042802	identical protein binding

0.83	GO:0005922	connexin complex
0.41	GO:0097449	astrocyte projection
0.40	GO:0016328	lateral plasma membrane
0.40	GO:0005829	cytosol
0.39	GO:0016324	apical plasma membrane
0.39	GO:0044297	cell body
0.39	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.30	GO:0016021	integral component of membrane

sp|P21996|PNEU_RAT
Pneumadin
Search

0.10

Pneumadin

sp|P22002|CAC1C_RAT
Voltage-dependent L-type calcium channel subunit alpha-1C
Search

CACNA1C

0.73	Voltage-dependent L-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.49	GO:0008016	regulation of heart contraction
0.48	GO:0086010	membrane depolarization during action potential
0.48	GO:0003012	muscle system process
0.47	GO:0007507	heart development
0.47	GO:0048598	embryonic morphogenesis
0.46	GO:0098900	regulation of action potential
0.46	GO:1903115	regulation of actin filament-based movement
0.46	GO:0086001	cardiac muscle cell action potential

0.82	GO:0005245	voltage-gated calcium channel activity
0.46	GO:0051393	alpha-actinin binding
0.43	GO:0005516	calmodulin binding
0.40	GO:1905030	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.36	GO:0051721	protein phosphatase 2A binding
0.36	GO:0044325	ion channel binding
0.36	GO:0031369	translation initiation factor binding
0.35	GO:0019904	protein domain specific binding
0.34	GO:0046872	metal ion binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.46	GO:0030315	T-tubule
0.45	GO:0014069	postsynaptic density
0.40	GO:0002095	caveolar macromolecular signaling complex
0.38	GO:0043198	dendritic shaft
0.38	GO:0030018	Z disc
0.37	GO:0043025	neuronal cell body
0.37	GO:0045211	postsynaptic membrane
0.36	GO:0042734	presynaptic membrane
0.34	GO:0005634	nucleus

sp|P22006|SVS2_RAT
Seminal vesicle secretory protein 2
Search

sp|P22057|PTGDS_RAT
Prostaglandin-H2 D-isomerase
Search

PTGDS

0.83	Prostaglandin D synthase

0.73	GO:0046457	prostanoid biosynthetic process
0.72	GO:0006693	prostaglandin metabolic process
0.69	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.66	GO:2000255	negative regulation of male germ cell proliferation
0.43	GO:0051384	response to glucocorticoid
0.39	GO:0044793	negative regulation by host of viral process
0.38	GO:0019369	arachidonic acid metabolic process
0.38	GO:0045071	negative regulation of viral genome replication
0.37	GO:0006303	double-strand break repair via nonhomologous end joining

0.77	GO:0004667	prostaglandin-D synthase activity
0.67	GO:0005501	retinoid binding
0.51	GO:0036094	small molecule binding
0.37	GO:0005515	protein binding
0.36	GO:0043168	anion binding

0.59	GO:0005791	rough endoplasmic reticulum
0.57	GO:0005576	extracellular region
0.55	GO:0031965	nuclear membrane
0.54	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005794	Golgi apparatus
0.39	GO:0031982	vesicle
0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:5.3.99.2	GO:0004667
0.77	KEGG:R02266	GO:0004667

sp|P22062|PIMT_RAT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Search

PCMT1

0.43	L-isoaspartyl protein carboxyl methyltransferase

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.35	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.35	GO:0045471	response to ethanol
0.35	GO:0071456	cellular response to hypoxia
0.34	GO:0007568	aging
0.34	GO:0046498	S-adenosylhomocysteine metabolic process
0.34	GO:0046500	S-adenosylmethionine metabolic process
0.34	GO:0030091	protein repair
0.32	GO:0042254	ribosome biogenesis

0.79	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
0.36	GO:0045296	cadherin binding

0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0031526	brush border membrane
0.35	GO:0043204	perikaryon
0.35	GO:0016323	basolateral plasma membrane
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.79

EC:2.1.1.77

GO:0004719

sp|P22063|CNTN2_RAT
Contactin-2
Search

CNTN2

0.97	LOW QUALITY PROTEIN: contactin-2

0.78	GO:0031175	neuron projection development
0.62	GO:0071206	establishment of protein localization to juxtaparanode region of axon
0.62	GO:0045163	clustering of voltage-gated potassium channels
0.61	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.61	GO:0021853	cerebral cortex GABAergic interneuron migration
0.61	GO:0031133	regulation of axon diameter
0.60	GO:0097090	presynaptic membrane organization
0.59	GO:0022010	central nervous system myelination
0.59	GO:0010954	positive regulation of protein processing
0.59	GO:0048710	regulation of astrocyte differentiation

0.57	GO:0043621	protein self-association
0.51	GO:0030246	carbohydrate binding
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0042802	identical protein binding

0.60	GO:0044224	juxtaparanode region of axon
0.60	GO:0033268	node of Ranvier
0.57	GO:0043209	myelin sheath
0.55	GO:0043025	neuronal cell body
0.53	GO:0008076	voltage-gated potassium channel complex
0.52	GO:0009986	cell surface
0.40	GO:0031225	anchored component of membrane
0.36	GO:0045202	synapse
0.35	GO:0045121	membrane raft
0.34	GO:0070062	extracellular exosome

sp|P22071|3BHS1_RAT
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
Search

0.50	3 beta-hydroxysteroid dehydrogenase isomerase VI

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0034754	cellular hormone metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.39	GO:0051412	response to corticosterone
0.39	GO:0010288	response to lead ion
0.38	GO:0033327	Leydig cell differentiation
0.38	GO:0034698	response to gonadotropin
0.38	GO:0021766	hippocampus development
0.38	GO:0035634	response to stilbenoid

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.54	GO:0102294	cholesterol dehydrogenase activity
0.54	GO:0004769	steroid delta-isomerase activity
0.38	GO:0010181	FMN binding
0.37	GO:0005496	steroid binding
0.37	GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity
0.36	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.35	GO:0051287	NAD binding
0.35	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.33	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.46	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.44	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.39	GO:0097425	smooth endoplasmic reticulum part
0.36	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.83

EC:1.1.1.145

GO:0003854

sp|P22072|3BHS2_RAT
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
Search

0.50	3 beta-hydroxysteroid dehydrogenase isomerase VI

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0034754	cellular hormone metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.38	GO:0014070	response to organic cyclic compound
0.38	GO:0010288	response to lead ion
0.38	GO:0033327	Leydig cell differentiation
0.38	GO:0034698	response to gonadotropin
0.38	GO:0021766	hippocampus development
0.37	GO:0008211	glucocorticoid metabolic process

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.54	GO:0102294	cholesterol dehydrogenase activity
0.54	GO:0004769	steroid delta-isomerase activity
0.38	GO:0010181	FMN binding
0.37	GO:0005496	steroid binding
0.37	GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity
0.36	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.35	GO:0051287	NAD binding
0.35	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.33	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.46	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.44	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.39	GO:0097425	smooth endoplasmic reticulum part
0.36	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.1.1.145

GO:0003854

sp|P22086|ADA2C_RAT
Alpha-2C adrenergic receptor
Search

ADRA2C

0.90	Alpha-2 adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.83	GO:0006940	regulation of smooth muscle contraction
0.83	GO:0019229	regulation of vasoconstriction
0.83	GO:0030168	platelet activation
0.47	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.47	GO:0051930	regulation of sensory perception of pain
0.46	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.46	GO:0045932	negative regulation of muscle contraction
0.46	GO:0032148	activation of protein kinase B activity
0.46	GO:1903524	positive regulation of blood circulation

0.85	GO:0004938	alpha2-adrenergic receptor activity
0.48	GO:0031694	alpha-2A adrenergic receptor binding
0.47	GO:0051379	epinephrine binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity

0.54	GO:0005886	plasma membrane
0.45	GO:0043679	axon terminus
0.44	GO:0030424	axon
0.37	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

sp|P22199|MCR_RAT
Mineralocorticoid receptor
Search

NR3C2

0.88	Mineralocorticoid receptor

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.41	GO:1904045	cellular response to aldosterone
0.41	GO:0006883	cellular sodium ion homeostasis
0.41	GO:0071386	cellular response to corticosterone stimulus
0.41	GO:0007588	excretion
0.41	GO:0060126	somatotropin secreting cell differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003707	steroid hormone receptor activity
0.50	GO:0005496	steroid binding
0.42	GO:0042562	hormone binding
0.36	GO:0005515	protein binding
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.41	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0043235	receptor complex
0.38	GO:0005829	cytosol

sp|P22273|IL6RA_RAT
Interleukin-6 receptor subunit alpha
Search

IL6R

0.97	Interleukin-6 receptor subunit alpha

0.78	GO:0019221	cytokine-mediated signaling pathway
0.67	GO:0071354	cellular response to interleukin-6
0.66	GO:0048661	positive regulation of smooth muscle cell proliferation
0.65	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.65	GO:0031018	endocrine pancreas development
0.65	GO:0032722	positive regulation of chemokine production
0.65	GO:0032755	positive regulation of interleukin-6 production
0.50	GO:0032966	negative regulation of collagen biosynthetic process
0.49	GO:0010536	positive regulation of activation of Janus kinase activity
0.45	GO:0043410	positive regulation of MAPK cascade

0.80	GO:0004896	cytokine receptor activity
0.72	GO:0070119	ciliary neurotrophic factor binding
0.70	GO:0019981	interleukin-6 binding
0.67	GO:0005138	interleukin-6 receptor binding
0.58	GO:0042803	protein homodimerization activity
0.56	GO:0019899	enzyme binding

0.69	GO:0005896	interleukin-6 receptor complex
0.69	GO:0070110	ciliary neurotrophic factor receptor complex
0.62	GO:0016324	apical plasma membrane
0.53	GO:0005576	extracellular region
0.42	GO:0009986	cell surface
0.42	GO:0032809	neuronal cell body membrane
0.38	GO:0016323	basolateral plasma membrane

sp|P22282|22P1_RAT
Cystatin-related protein 1
Search

0.53

Cystatin

0.76

GO:0010951

negative regulation of endopeptidase activity

0.83

GO:0004869

cysteine-type endopeptidase inhibitor activity

sp|P22283|22P2_RAT
Cystatin-related protein 2
Search

0.53

Cystatin

0.76

GO:0010951

negative regulation of endopeptidase activity

0.83

GO:0004869

cysteine-type endopeptidase inhibitor activity

sp|P22288|GCH1_RAT
GTP cyclohydrolase 1
Search

GCH1

0.44	GTP cyclohydrolase I

0.75	GO:0046654	tetrahydrofolate biosynthetic process
0.57	GO:0014916	regulation of lung blood pressure
0.56	GO:0042416	dopamine biosynthetic process
0.55	GO:0051000	positive regulation of nitric-oxide synthase activity
0.55	GO:0010460	positive regulation of heart rate
0.55	GO:2000121	regulation of removal of superoxide radicals
0.55	GO:0050884	neuromuscular process controlling posture
0.53	GO:0046146	tetrahydrobiopterin metabolic process
0.53	GO:0034312	diol biosynthetic process
0.53	GO:0034341	response to interferon-gamma

0.79	GO:0003934	GTP cyclohydrolase I activity
0.55	GO:0051019	mitogen-activated protein kinase binding
0.49	GO:0042803	protein homodimerization activity
0.47	GO:0032550	purine ribonucleoside binding
0.47	GO:0019001	guanyl nucleotide binding
0.46	GO:0003924	GTPase activity
0.46	GO:0008270	zinc ion binding
0.42	GO:0030742	GTP-dependent protein binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0031965	nuclear membrane
0.49	GO:0005737	cytoplasm
0.48	GO:0097708	intracellular vesicle
0.47	GO:0005654	nucleoplasm
0.43	GO:0043234	protein complex
0.35	GO:0044306	neuron projection terminus

0.79	EC:3.5.4.16	GO:0003934
0.79	KEGG:R00424	GO:0003934

sp|P22355|PSPB_RAT
Pulmonary surfactant-associated protein B
Search

SFTPB

0.96	Pulmonary surfactant-associated protein B

0.71	GO:0006665	sphingolipid metabolic process
0.59	GO:0007585	respiratory gaseous exchange
0.52	GO:0009887	animal organ morphogenesis
0.50	GO:0043085	positive regulation of catalytic activity
0.45	GO:0050828	regulation of liquid surface tension
0.45	GO:0033189	response to vitamin A
0.44	GO:0071732	cellular response to nitric oxide
0.44	GO:0055093	response to hyperoxia
0.44	GO:0070741	response to interleukin-6
0.44	GO:0070849	response to epidermal growth factor

0.54	GO:0001664	G-protein coupled receptor binding
0.51	GO:0008047	enzyme activator activity

0.71	GO:0005764	lysosome
0.59	GO:0097208	alveolar lamellar body
0.57	GO:0005771	multivesicular body
0.52	GO:0005615	extracellular space
0.43	GO:0031906	late endosome lumen
0.41	GO:0045334	clathrin-coated endocytic vesicle
0.38	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005654	nucleoplasm

sp|P22388|EDN1_RAT
Endothelin-1
Search

EDN1

0.97	Preproendothelin

0.85	GO:0019229	regulation of vasoconstriction
0.69	GO:0042310	vasoconstriction
0.68	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity
0.67	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.66	GO:0014820	tonic smooth muscle contraction
0.65	GO:0014821	phasic smooth muscle contraction
0.65	GO:0010460	positive regulation of heart rate
0.65	GO:0042313	protein kinase C deactivation
0.64	GO:0030185	nitric oxide transport
0.64	GO:0046457	prostanoid biosynthetic process

0.68	GO:0031708	endothelin B receptor binding
0.65	GO:0031707	endothelin A receptor binding
0.59	GO:0005179	hormone activity
0.57	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.45	GO:0048237	rough endoplasmic reticulum lumen
0.44	GO:0033093	Weibel-Palade body
0.43	GO:0045178	basal part of cell
0.35	GO:0030133	transport vesicle
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0051353

sp|P22443|CP19A_RAT
Aromatase
Search

CYP19A1

0.81

Aromatase

0.62	GO:2000866	positive regulation of estradiol secretion
0.61	GO:0006710	androgen catabolic process
0.61	GO:0002677	negative regulation of chronic inflammatory response
0.61	GO:0010760	negative regulation of macrophage chemotaxis
0.60	GO:0061370	testosterone biosynthetic process
0.60	GO:0060736	prostate gland growth
0.59	GO:0030540	female genitalia development
0.59	GO:0060065	uterus development
0.57	GO:0008585	female gonad development
0.55	GO:0030879	mammary gland development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0019825	oxygen binding
0.33	GO:0009055	electron transfer activity

0.50	GO:0005783	endoplasmic reticulum
0.39	GO:0044297	cell body
0.38	GO:0043195	terminal bouton
0.38	GO:0030425	dendrite
0.35	GO:0044309	neuron spine
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0008021	synaptic vesicle
0.35	GO:0098794	postsynapse
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005829	cytosol

0.68

GO:0016705

sp|P22449|HNF4A_RAT
Hepatocyte nuclear factor 4-alpha
Search

HNF4A

0.94	Hepatocyte nuclear factor 4-alpha

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.76	GO:0030522	intracellular receptor signaling pathway
0.59	GO:2000189	positive regulation of cholesterol homeostasis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0055091	phospholipid homeostasis
0.57	GO:0023019	signal transduction involved in regulation of gene expression
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0070328	triglyceride homeostasis
0.56	GO:0010470	regulation of gastrulation

0.80	GO:0003707	steroid hormone receptor activity
0.78	GO:0004879	nuclear receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.55	GO:0005504	fatty acid binding
0.55	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.47	GO:0043233	organelle lumen
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.33	GO:0005667	transcription factor complex

0.35

EC:3.1.2.2

GO:0016290

sp|P22462|KCNC2_RAT
Potassium voltage-gated channel subfamily C member 2
Search

KCNC2

0.89	LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily C member 2

0.72	GO:0071805	potassium ion transmembrane transport
0.71	GO:0051260	protein homooligomerization
0.71	GO:0034765	regulation of ion transmembrane transport
0.48	GO:0046928	regulation of neurotransmitter secretion
0.45	GO:0038060	nitric oxide-cGMP-mediated signaling pathway
0.43	GO:0071732	cellular response to nitric oxide
0.43	GO:0021759	globus pallidus development
0.42	GO:0051291	protein heterooligomerization
0.42	GO:0032026	response to magnesium ion
0.42	GO:1990089	response to nerve growth factor

0.76	GO:0005249	voltage-gated potassium channel activity
0.43	GO:0044325	ion channel binding
0.36	GO:0019894	kinesin binding

0.76	GO:0008076	voltage-gated potassium channel complex
0.50	GO:0043679	axon terminus
0.47	GO:0031594	neuromuscular junction
0.44	GO:0032809	neuronal cell body membrane
0.43	GO:0030673	axolemma
0.43	GO:0030425	dendrite
0.42	GO:0043204	perikaryon
0.42	GO:0016323	basolateral plasma membrane
0.41	GO:0016324	apical plasma membrane
0.40	GO:0042734	presynaptic membrane

sp|P22509|FBRL_RAT
rRNA 2'-O-methyltransferase fibrillarin
Search

FBL

0.77	LOW QUALITY PROTEIN: rRNA 2'-O-methyltransferase fibrillarin

0.66	GO:0006364	rRNA processing
0.64	GO:0008033	tRNA processing
0.61	GO:0032259	methylation
0.55	GO:0016074	snoRNA metabolic process
0.54	GO:0048254	snoRNA localization
0.50	GO:0016570	histone modification
0.50	GO:0008213	protein alkylation
0.47	GO:0043628	ncRNA 3'-end processing
0.43	GO:0009451	RNA modification
0.38	GO:0001649	osteoblast differentiation

0.61	GO:0008168	methyltransferase activity
0.57	GO:0003723	RNA binding
0.53	GO:0001094	TFIID-class transcription factor binding
0.51	GO:0051117	ATPase binding
0.45	GO:0140102	catalytic activity, acting on a rRNA
0.43	GO:0140096	catalytic activity, acting on a protein

0.57	GO:0001650	fibrillar center
0.55	GO:0015030	Cajal body
0.53	GO:0001652	granular component
0.50	GO:0031428	box C/D snoRNP complex
0.48	GO:0032040	small-subunit processome
0.41	GO:0001651	dense fibrillar component
0.37	GO:0070062	extracellular exosome
0.36	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.61

GO:0008168

sp|P22717|GCYB2_RAT
Guanylate cyclase soluble subunit beta-2
Search

0.97	Guanylate cyclase soluble subunit beta-2

0.82	GO:0006182	cGMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.37	GO:0006468	protein phosphorylation
0.34	GO:0007631	feeding behavior
0.34	GO:0070482	response to oxygen levels

0.83	GO:0004383	guanylate cyclase activity
0.61	GO:0020037	heme binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.48	GO:0004016	adenylate cyclase activity
0.37	GO:0004672	protein kinase activity
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0043168	anion binding
0.35	GO:0008144	drug binding
0.33	GO:0046872	metal ion binding

0.51	GO:0008074	guanylate cyclase complex, soluble
0.40	GO:0005886	plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.30	GO:0016021	integral component of membrane

0.83

GO:0004383

sp|P22734|COMT_RAT
Catechol O-methyltransferase
Search

COMT

0.54	Membrane bound catechol-O-methyltransferase

0.81	GO:0006584	catecholamine metabolic process
0.70	GO:0042135	neurotransmitter catabolic process
0.63	GO:0032259	methylation
0.54	GO:0016036	cellular response to phosphate starvation
0.52	GO:0019614	catechol-containing compound catabolic process
0.50	GO:0097164	ammonium ion metabolic process
0.48	GO:0042737	drug catabolic process
0.46	GO:1901565	organonitrogen compound catabolic process
0.43	GO:0050668	positive regulation of homocysteine metabolic process
0.42	GO:0045963	negative regulation of dopamine metabolic process

0.84	GO:0016206	catechol O-methyltransferase activity
0.61	GO:0000287	magnesium ion binding
0.45	GO:0102084	L-dopa O-methyltransferase activity
0.45	GO:0102938	orcinol O-methyltransferase activity
0.33	GO:0005515	protein binding

0.44	GO:0005739	mitochondrion
0.40	GO:0043197	dendritic spine
0.39	GO:0044297	cell body
0.39	GO:0030424	axon
0.39	GO:0045211	postsynaptic membrane
0.37	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.84

EC:2.1.1.6

GO:0016206

sp|P22756|GRIK1_RAT
Glutamate receptor ionotropic, kainate 1
Search

GRIK1

0.94	Glutamate ionotropic receptor kainate type subunit 1

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.37	GO:0051966	regulation of synaptic transmission, glutamatergic
0.36	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.36	GO:0014054	positive regulation of gamma-aminobutyric acid secretion
0.36	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.36	GO:0060080	inhibitory postsynaptic potential
0.36	GO:0007399	nervous system development
0.36	GO:0048172	regulation of short-term neuronal synaptic plasticity

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.37	GO:0099094	ligand-gated cation channel activity
0.37	GO:0005272	sodium channel activity
0.36	GO:0098782	mechanosensitived potassium channel activity
0.36	GO:0016595	glutamate binding
0.35	GO:0022843	voltage-gated cation channel activity
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0008144	drug binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.36	GO:0032983	kainate selective glutamate receptor complex
0.35	GO:0042734	presynaptic membrane
0.35	GO:0043195	terminal bouton
0.35	GO:0014069	postsynaptic density
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite

sp|P22771|GLRA2_RAT
Glycine receptor subunit alpha-2
Search

GLRA2

0.90	Glycine receptor subunit alpha-2

0.69	GO:0060079	excitatory postsynaptic potential
0.67	GO:1902476	chloride transmembrane transport
0.61	GO:0043200	response to amino acid
0.58	GO:0071294	cellular response to zinc ion
0.57	GO:0071361	cellular response to ethanol
0.57	GO:0007218	neuropeptide signaling pathway
0.53	GO:0071229	cellular response to acid chemical
0.53	GO:0071417	cellular response to organonitrogen compound
0.52	GO:0060012	synaptic transmission, glycinergic
0.35	GO:0007416	synapse assembly

0.85	GO:0016594	glycine binding
0.77	GO:0016934	extracellularly glycine-gated chloride channel activity
0.76	GO:0022824	transmitter-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.34	GO:0046872	metal ion binding

0.68	GO:0098794	postsynapse
0.66	GO:0005887	integral component of plasma membrane
0.65	GO:0097060	synaptic membrane
0.39	GO:0034707	chloride channel complex
0.37	GO:0030054	cell junction
0.36	GO:0042995	cell projection
0.34	GO:0043204	perikaryon

sp|P22789|ST2A2_RAT
Alcohol sulfotransferase A
Search

0.54	Alcohol sulfotransferase A

0.52	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.51	GO:0008202	steroid metabolic process
0.50	GO:0051923	sulfation
0.49	GO:0006068	ethanol catabolic process
0.41	GO:0071305	cellular response to vitamin D
0.41	GO:0017085	response to insecticide
0.41	GO:0045606	positive regulation of epidermal cell differentiation
0.41	GO:0014823	response to activity
0.40	GO:0042403	thyroid hormone metabolic process
0.39	GO:0007568	aging

0.78	GO:0008146	sulfotransferase activity
0.42	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.42	GO:1990239	steroid hormone binding
0.40	GO:0015485	cholesterol binding
0.35	GO:0008144	drug binding
0.34	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.46	GO:0005829	cytosol
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0043229	intracellular organelle
0.35	GO:0012505	endomembrane system
0.35	GO:0043230	extracellular organelle
0.34	GO:0005615	extracellular space
0.33	GO:0031975	envelope
0.33	GO:0044422	organelle part
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043228	non-membrane-bounded organelle

0.78

GO:0008146

sp|P22791|HMCS2_RAT
Hydroxymethylglutaryl-CoA synthase, mitochondrial
Search

HMGCS2

0.67	3-hydroxy-3-methylglutaryl coenzyme A synthase

0.78	GO:0016126	sterol biosynthetic process
0.71	GO:0008299	isoprenoid biosynthetic process
0.44	GO:0014003	oligodendrocyte development
0.35	GO:0033197	response to vitamin E
0.35	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.35	GO:0071397	cellular response to cholesterol
0.35	GO:0009645	response to low light intensity stimulus
0.35	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.34	GO:0046690	response to tellurium ion
0.34	GO:0008584	male gonad development

0.83	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.34	GO:0008009	chemokine activity
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0043177	organic acid binding
0.33	GO:0016853	isomerase activity
0.32	GO:0008144	drug binding

0.43	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.33	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.83	EC:2.3.3.10	GO:0004421
0.83	KEGG:R01978	GO:0004421

sp|P22829|NR4A1_RAT
Nuclear receptor subfamily 4 group A member 1
Search

NR4A1

0.95	Orphan nuclear receptor HMR

0.80	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.62	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.58	GO:0045444	fat cell differentiation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0035914	skeletal muscle cell differentiation
0.55	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0046982	protein heterodimerization activity
0.51	GO:0042803	protein homodimerization activity
0.47	GO:0035259	glucocorticoid receptor binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.49	GO:0005829	cytosol
0.49	GO:0012505	endomembrane system
0.46	GO:0031967	organelle envelope
0.46	GO:0031090	organelle membrane
0.39	GO:0070013	intracellular organelle lumen

sp|P22831|SYNPR_RAT
Synaptoporin
Search

SYNPR

0.97	Synaptophysin IIa

0.52	GO:0048168	regulation of neuronal synaptic plasticity
0.45	GO:0048488	synaptic vesicle endocytosis
0.42	GO:0071310	cellular response to organic substance
0.39	GO:2000474	regulation of opioid receptor signaling pathway
0.34	GO:0048499	synaptic vesicle membrane organization
0.34	GO:0016188	synaptic vesicle maturation
0.34	GO:0045920	negative regulation of exocytosis
0.34	GO:0043029	T cell homeostasis
0.34	GO:0050856	regulation of T cell receptor signaling pathway
0.33	GO:0007601	visual perception

0.46	GO:0042169	SH2 domain binding
0.45	GO:0015485	cholesterol binding
0.42	GO:0042802	identical protein binding
0.36	GO:0017075	syntaxin-1 binding
0.34	GO:0008331	high voltage-gated calcium channel activity
0.34	GO:0043621	protein self-association
0.33	GO:0046914	transition metal ion binding
0.33	GO:0032403	protein complex binding
0.33	GO:0051020	GTPase binding
0.33	GO:0003924	GTPase activity

0.82	GO:0008021	synaptic vesicle
0.54	GO:0099501	exocytic vesicle membrane
0.47	GO:0031301	integral component of organelle membrane
0.46	GO:0060076	excitatory synapse
0.45	GO:0042734	presynaptic membrane
0.45	GO:0043005	neuron projection
0.45	GO:0031594	neuromuscular junction
0.44	GO:0048786	presynaptic active zone
0.42	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0030054	cell junction

sp|P22909|ADA2A_RAT
Alpha-2A adrenergic receptor
Search

ADRA2A

0.69	Adrenoceptor alpha 2A

0.85	GO:0071875	adrenergic receptor signaling pathway
0.82	GO:0006940	regulation of smooth muscle contraction
0.81	GO:0019229	regulation of vasoconstriction
0.81	GO:0030168	platelet activation
0.73	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.73	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.71	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.71	GO:0050995	negative regulation of lipid catabolic process
0.71	GO:0032148	activation of protein kinase B activity
0.70	GO:0030818	negative regulation of cAMP biosynthetic process

0.85	GO:0004935	adrenergic receptor activity
0.75	GO:0031696	alpha-2C adrenergic receptor binding
0.74	GO:0032795	heterotrimeric G-protein binding
0.73	GO:0051380	norepinephrine binding
0.73	GO:0051379	epinephrine binding
0.72	GO:0031996	thioesterase binding
0.63	GO:0019901	protein kinase binding
0.61	GO:0042803	protein homodimerization activity
0.60	GO:0046982	protein heterodimerization activity

0.63	GO:0043235	receptor complex
0.55	GO:0005887	integral component of plasma membrane
0.43	GO:0005737	cytoplasm

sp|P22934|TNR1A_RAT
Tumor necrosis factor receptor superfamily member 1A
Search

TNFRSF1A

0.94	Tumor necrosis factor type I

0.84	GO:0006692	prostanoid metabolic process
0.84	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.79	GO:0006954	inflammatory response
0.65	GO:1903140	regulation of establishment of endothelial barrier
0.63	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.63	GO:0071260	cellular response to mechanical stimulus
0.62	GO:0050728	negative regulation of inflammatory response
0.62	GO:0097190	apoptotic signaling pathway
0.62	GO:0050729	positive regulation of inflammatory response
0.61	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.85	GO:0005031	tumor necrosis factor-activated receptor activity
0.55	GO:0043120	tumor necrosis factor binding
0.39	GO:0005272	sodium channel activity
0.39	GO:0042802	identical protein binding
0.37	GO:0099094	ligand-gated cation channel activity
0.34	GO:0046872	metal ion binding
0.30	GO:0002020	protease binding
0.30	GO:0032403	protein complex binding

0.59	GO:0098857	membrane microdomain
0.58	GO:0043235	receptor complex
0.57	GO:0000139	Golgi membrane
0.56	GO:0009986	cell surface
0.55	GO:0005615	extracellular space
0.44	GO:0005887	integral component of plasma membrane
0.42	GO:0005739	mitochondrion
0.30	GO:0120025	plasma membrane bounded cell projection
0.30	GO:0097458	neuron part
0.30	GO:0043234	protein complex

sp|P22985|XDH_RAT
Xanthine dehydrogenase/oxidase
Search

XDH

0.52	XDH xanthine dehydrogenase

0.65	GO:0009115	xanthine catabolic process
0.62	GO:2001213	negative regulation of vasculogenesis
0.60	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.59	GO:0045602	negative regulation of endothelial cell differentiation
0.59	GO:1900745	positive regulation of p38MAPK cascade
0.58	GO:0022900	electron transport chain
0.58	GO:0001937	negative regulation of endothelial cell proliferation
0.57	GO:0051898	negative regulation of protein kinase B signaling
0.57	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:2000379	positive regulation of reactive oxygen species metabolic process

0.79	GO:0016727	oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
0.78	GO:0004854	xanthine dehydrogenase activity
0.74	GO:0043546	molybdopterin cofactor binding
0.68	GO:0051537	2 iron, 2 sulfur cluster binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.64	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.62	GO:0005506	iron ion binding
0.59	GO:0009055	electron transfer activity
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0030151	molybdenum ion binding

0.55	GO:0016529	sarcoplasmic reticulum
0.45	GO:0005829	cytosol
0.43	GO:0005615	extracellular space
0.40	GO:0005777	peroxisome
0.37	GO:0002197	xanthine dehydrogenase complex
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.17.3

GO:0016727

sp|P23097|MMP13_RAT
Collagenase 3 (Fragment)
Search

MMP13

0.72	Matrix metalloproteinase

0.82	GO:0030574	collagen catabolic process
0.61	GO:0006508	proteolysis
0.59	GO:0022617	extracellular matrix disassembly
0.57	GO:0003417	growth plate cartilage development
0.56	GO:0001958	endochondral ossification
0.56	GO:0030282	bone mineralization
0.46	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.44	GO:0032461	positive regulation of protein oligomerization
0.42	GO:0030334	regulation of cell migration
0.42	GO:0044267	cellular protein metabolic process

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.56	GO:0005518	collagen binding
0.50	GO:0005509	calcium ion binding
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0001968	fibronectin binding
0.36	GO:0050750	low-density lipoprotein particle receptor binding
0.36	GO:0048306	calcium-dependent protein binding
0.34	GO:0001047	core promoter binding
0.33	GO:0043565	sequence-specific DNA binding

0.74	GO:0031012	extracellular matrix
0.41	GO:0005581	collagen trimer
0.38	GO:0005615	extracellular space
0.36	GO:0046581	intercellular canaliculus
0.35	GO:0005764	lysosome
0.34	GO:0005794	Golgi apparatus
0.34	GO:1903561	extracellular vesicle
0.34	GO:0030425	dendrite
0.34	GO:0044297	cell body
0.33	GO:0005634	nucleus

0.70

GO:0004222

sp|P23265|O1078_RAT
Olfactory receptor 1078
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P23266|O1361_RAT
Olfactory receptor 1361
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0032467	positive regulation of cytokinesis

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005549	odorant binding
0.33	GO:0005509	calcium ion binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P23267|OL287_RAT
Olfactory receptor 287
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.42	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P23268|O1082_RAT
Olfactory receptor 1082
Search

0.45	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.74	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005549	odorant binding

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P23269|O1496_RAT
Olfactory receptor 1496
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007020	microtubule nucleation

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0043015	gamma-tubulin binding

0.55	GO:0005886	plasma membrane
0.34	GO:0000922	spindle pole
0.34	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

sp|P23270|OL226_RAT
Olfactory receptor 226
Search

0.44	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.37	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P23271|O1493_RAT
Olfactory receptor 1493
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007020	microtubule nucleation

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0043015	gamma-tubulin binding

0.55	GO:0005886	plasma membrane
0.34	GO:0000922	spindle pole
0.34	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

sp|P23272|OLFI9_RAT
Olfactory receptor-like protein I9
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0007020	microtubule nucleation

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.36	GO:0043015	gamma-tubulin binding

0.55	GO:0005886	plasma membrane
0.35	GO:0000922	spindle pole
0.35	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

sp|P23273|O1500_RAT
Olfactory receptor 1500
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007020	microtubule nucleation

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0043015	gamma-tubulin binding

0.55	GO:0005886	plasma membrane
0.34	GO:0000922	spindle pole
0.34	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

sp|P23274|O1468_RAT
Olfactory receptor 1468
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007020	microtubule nucleation

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0043015	gamma-tubulin binding

0.55	GO:0005886	plasma membrane
0.34	GO:0000922	spindle pole
0.34	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

sp|P23347|B3A2_RAT
Anion exchange protein 2
Search

SLC4A2

0.65	Anion exchange protein 2

0.69	GO:0098656	anion transmembrane transport
0.69	GO:0015698	inorganic anion transport
0.48	GO:0015701	bicarbonate transport
0.48	GO:0051453	regulation of intracellular pH
0.45	GO:0035725	sodium ion transmembrane transport
0.38	GO:0048565	digestive tract development
0.38	GO:0007283	spermatogenesis

0.82	GO:0005452	inorganic anion exchanger activity
0.50	GO:0008510	sodium:bicarbonate symporter activity
0.49	GO:0015301	anion:anion antiporter activity
0.37	GO:0019899	enzyme binding
0.36	GO:0015108	chloride transmembrane transporter activity
0.35	GO:0015280	ligand-gated sodium channel activity

0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0016323	basolateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.37	GO:0005925	focal adhesion

sp|P23348|B3A3_RAT
Anion exchange protein 3
Search

SLC4A3

0.64	Anion exchange protein 3

0.69	GO:0015698	inorganic anion transport
0.69	GO:0098656	anion transmembrane transport
0.57	GO:0051453	regulation of intracellular pH
0.51	GO:0015701	bicarbonate transport
0.47	GO:0035725	sodium ion transmembrane transport
0.37	GO:0048565	digestive tract development
0.37	GO:0007283	spermatogenesis

0.83	GO:0005452	inorganic anion exchanger activity
0.56	GO:0015301	anion:anion antiporter activity
0.52	GO:0008510	sodium:bicarbonate symporter activity
0.37	GO:0019899	enzyme binding
0.35	GO:0015108	chloride transmembrane transporter activity

0.43	GO:0005887	integral component of plasma membrane
0.38	GO:0016323	basolateral plasma membrane
0.37	GO:0016324	apical plasma membrane
0.36	GO:0005925	focal adhesion

sp|P23358|RL12_RAT
60S ribosomal protein L12
Search

RPL12

0.72	Alpha-tubulin N-acetyltransferase 1 (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000027	ribosomal large subunit assembly
0.34	GO:0045901	positive regulation of translational elongation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0019843	rRNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016740	transferase activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|P23363|BDNF_RAT
Brain-derived neurotrophic factor
Search

BDNF

0.59	Brain-derived neurotrophic factor

0.75	GO:0010469	regulation of receptor activity
0.51	GO:1900122	positive regulation of receptor binding
0.51	GO:0048672	positive regulation of collateral sprouting
0.51	GO:0048668	collateral sprouting
0.49	GO:0051965	positive regulation of synapse assembly
0.49	GO:0007416	synapse assembly
0.43	GO:0043524	negative regulation of neuron apoptotic process
0.41	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.41	GO:0007267	cell-cell signaling
0.38	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway

0.78	GO:0008083	growth factor activity
0.45	GO:0005169	neurotrophin TRKB receptor binding

0.66	GO:0005576	extracellular region
0.47	GO:0016607	nuclear speck
0.41	GO:0005739	mitochondrion
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0031410	cytoplasmic vesicle
0.36	GO:0030425	dendrite
0.36	GO:0030424	axon
0.36	GO:0098794	postsynapse
0.35	GO:0043204	perikaryon
0.35	GO:0043679	axon terminus

sp|P23377|FURIN_RAT
Furin
Search

FURIN

0.95	Truncated furin endoprotease

0.62	GO:0090472	dibasic protein processing
0.61	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.61	GO:0032902	nerve growth factor production
0.60	GO:0032911	negative regulation of transforming growth factor beta1 production
0.59	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process
0.57	GO:0016486	peptide hormone processing
0.57	GO:0031638	zymogen activation
0.54	GO:0008283	cell proliferation
0.54	GO:0006465	signal peptide processing
0.52	GO:0010951	negative regulation of endopeptidase activity

0.69	GO:0004252	serine-type endopeptidase activity
0.60	GO:0048406	nerve growth factor binding
0.56	GO:0002020	protease binding
0.54	GO:0042277	peptide binding
0.54	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0046872	metal ion binding

0.55	GO:0030140	trans-Golgi network transport vesicle
0.54	GO:0098857	membrane microdomain
0.54	GO:0005802	trans-Golgi network
0.52	GO:0009986	cell surface
0.51	GO:0000139	Golgi membrane
0.49	GO:0005783	endoplasmic reticulum
0.40	GO:0010008	endosome membrane
0.38	GO:0005576	extracellular region
0.36	GO:0005796	Golgi lumen
0.35	GO:0005886	plasma membrane

0.69

GO:0004252

sp|P23385|GRM1_RAT
Metabotropic glutamate receptor 1
Search

GRM1

0.81	Bifunctional metabotropic receptor for extracellular calcium and glutamate

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration
0.60	GO:0071257	cellular response to electrical stimulus
0.59	GO:0051930	regulation of sensory perception of pain
0.57	GO:0019233	sensory perception of pain
0.56	GO:0000187	activation of MAPK activity
0.56	GO:0000186	activation of MAPKK activity
0.56	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.55	GO:0007626	locomotory behavior
0.54	GO:0007215	glutamate receptor signaling pathway

0.71	GO:0004930	G-protein coupled receptor activity
0.61	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.54	GO:0008066	glutamate receptor activity
0.38	GO:0042802	identical protein binding
0.37	GO:0030331	estrogen receptor binding

0.62	GO:0038038	G-protein coupled receptor homodimeric complex
0.57	GO:0014069	postsynaptic density
0.55	GO:0030425	dendrite
0.50	GO:0042734	presynaptic membrane
0.45	GO:0005634	nucleus
0.39	GO:0044309	neuron spine
0.38	GO:0045211	postsynaptic membrane
0.36	GO:0043025	neuronal cell body
0.36	GO:0030424	axon
0.33	GO:0044422	organelle part

sp|P23441|NKX21_RAT
Homeobox protein Nkx-2.1
Search

NKX2-1

0.89	Thyroid transcription factor 1

0.63	GO:0021536	diencephalon development
0.62	GO:0021761	limbic system development
0.59	GO:0060486	Clara cell differentiation
0.59	GO:0030878	thyroid gland development
0.58	GO:0060510	Type II pneumocyte differentiation
0.58	GO:0021798	forebrain dorsal/ventral pattern formation
0.58	GO:0060430	lung saccule development
0.58	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.58	GO:0021892	cerebral cortex GABAergic interneuron differentiation
0.58	GO:0060441	epithelial tube branching involved in lung morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0044213	intronic transcription regulatory region DNA binding
0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.55	GO:0001047	core promoter binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.50	GO:0019899	enzyme binding
0.37	GO:0008134	transcription factor binding
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.39	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part

sp|P23457|DIDH_RAT
3-alpha-hydroxysteroid dehydrogenase
Search

0.59	3-alpha-hydroxysteroid dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0044597	daunorubicin metabolic process
0.49	GO:0071395	cellular response to jasmonic acid stimulus
0.48	GO:0044598	doxorubicin metabolic process
0.47	GO:0008202	steroid metabolic process
0.46	GO:0071798	response to prostaglandin D
0.45	GO:1900053	negative regulation of retinoic acid biosynthetic process
0.45	GO:0016488	farnesol catabolic process
0.44	GO:0071379	cellular response to prostaglandin stimulus
0.44	GO:2000224	regulation of testosterone biosynthetic process

0.54	GO:0016491	oxidoreductase activity
0.42	GO:0032052	bile acid binding
0.36	GO:0005496	steroid binding
0.35	GO:0070401	NADP+ binding
0.35	GO:0070402	NADPH binding
0.35	GO:0015125	bile acid transmembrane transporter activity
0.33	GO:0005515	protein binding

0.39	GO:0070062	extracellular exosome
0.39	GO:0005829	cytosol
0.38	GO:0005634	nucleus

0.54

GO:0016491

sp|P23505|GP42_RAT
Cell surface glycoprotein gp42
Search

FCRL6

0.71	Fc receptor-like protein 6

0.72	GO:0042289	MHC class II protein binding
0.68	GO:0019903	protein phosphatase binding

0.66	GO:0009897	external side of plasma membrane
0.48	GO:0043235	receptor complex
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P23512|FOXA1_RAT
Hepatocyte nuclear factor 3-alpha
Search

FOXA2

0.96	Hepatocyte nuclear factor 3-alpha

0.63	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.60	GO:1902691	respiratory basal cell differentiation
0.59	GO:0061144	alveolar secondary septum development
0.59	GO:0060741	prostate gland stromal morphogenesis
0.59	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development
0.58	GO:0060743	epithelial cell maturation involved in prostate gland development
0.58	GO:0051090	regulation of DNA binding transcription factor activity
0.58	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
0.58	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.57	GO:0021904	dorsal/ventral neural tube patterning

0.76	GO:0019904	protein domain specific binding
0.72	GO:0008134	transcription factor binding
0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0044212	transcription regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0005902	microvillus
0.51	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.45	GO:0030054	cell junction
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0005737	cytoplasm

sp|P23514|COPB_RAT
Coatomer subunit beta
Search

COPB1

0.62	Coatomer subunit beta

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.45	GO:0030903	notochord development
0.45	GO:0061053	somite development
0.35	GO:0002283	neutrophil activation involved in immune response
0.35	GO:0002446	neutrophil mediated immunity
0.33	GO:0032940	secretion by cell
0.33	GO:0016032	viral process
0.33	GO:0007165	signal transduction

0.61	GO:0005198	structural molecule activity
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0030126	COPI vesicle coat
0.72	GO:0000139	Golgi membrane
0.48	GO:0005829	cytosol
0.41	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0005886	plasma membrane
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0030133	transport vesicle
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

sp|P23562|B3AT_RAT
Band 3 anion transport protein
Search

SLC4A1

0.64	Anion exchange protein (Fragment)

0.69	GO:0015698	inorganic anion transport
0.68	GO:0098656	anion transmembrane transport
0.59	GO:0015701	bicarbonate transport
0.47	GO:0051453	regulation of intracellular pH
0.46	GO:0098660	inorganic ion transmembrane transport
0.44	GO:0006814	sodium ion transport
0.40	GO:0098655	cation transmembrane transport
0.36	GO:0010037	response to carbon dioxide
0.36	GO:0010446	response to alkaline pH
0.36	GO:0014823	response to activity

0.82	GO:0005452	inorganic anion exchanger activity
0.59	GO:0015106	bicarbonate transmembrane transporter activity
0.58	GO:0030506	ankyrin binding
0.58	GO:0015301	anion:anion antiporter activity
0.53	GO:0015108	chloride transmembrane transporter activity
0.51	GO:0042803	protein homodimerization activity
0.45	GO:0015296	anion:cation symporter activity
0.44	GO:0015081	sodium ion transmembrane transporter activity
0.36	GO:0008022	protein C-terminus binding
0.36	GO:0043495	protein membrane anchor

0.56	GO:0016323	basolateral plasma membrane
0.54	GO:0030863	cortical cytoskeleton
0.49	GO:0005887	integral component of plasma membrane
0.43	GO:0030018	Z disc
0.38	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome
0.37	GO:0016324	apical plasma membrane
0.36	GO:0014704	intercalated disc
0.35	GO:0009986	cell surface

sp|P23565|AINX_RAT
Alpha-internexin
Search

INA

0.94	Internexin neuronal intermediate filament protein alpha

0.73	GO:0007399	nervous system development
0.59	GO:0120036	plasma membrane bounded cell projection organization
0.58	GO:0060052	neurofilament cytoskeleton organization
0.58	GO:0048468	cell development
0.55	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.38	GO:0048857	neural nucleus development
0.38	GO:0060322	head development
0.37	GO:0045110	intermediate filament bundle assembly
0.37	GO:0048513	animal organ development

0.62	GO:0005198	structural molecule activity
0.36	GO:0005515	protein binding
0.34	GO:0015643	toxic substance binding

0.85	GO:0005883	neurofilament
0.55	GO:0043209	myelin sheath
0.54	GO:0036464	cytoplasmic ribonucleoprotein granule
0.54	GO:0031965	nuclear membrane
0.49	GO:0097418	neurofibrillary tangle
0.49	GO:0005654	nucleoplasm
0.36	GO:0005615	extracellular space
0.36	GO:0030424	axon
0.35	GO:0031594	neuromuscular junction
0.35	GO:0014069	postsynaptic density

sp|P23570|IRF1_RAT
Interferon regulatory factor 1
Search

IRF1

0.92	Interferon regulatory factor

0.78	GO:0008285	negative regulation of cell proliferation
0.77	GO:0006915	apoptotic process
0.71	GO:0050776	regulation of immune response
0.65	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation
0.65	GO:0045590	negative regulation of regulatory T cell differentiation
0.64	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.64	GO:0035458	cellular response to interferon-beta
0.63	GO:0043374	CD8-positive, alpha-beta T cell differentiation
0.63	GO:0032728	positive regulation of interferon-beta production
0.63	GO:0060333	interferon-gamma-mediated signaling pathway

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:1990837	sequence-specific double-stranded DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0030545	receptor regulator activity

0.61	GO:0005634	nucleus
0.54	GO:0000785	chromatin
0.51	GO:0070013	intracellular organelle lumen
0.41	GO:0005737	cytoplasm
0.35	GO:0005925	focal adhesion
0.33	GO:0005576	extracellular region

sp|P23571|3MG_RAT
DNA-3-methyladenine glycosylase (Fragment)
Search

MPG

0.51	N-methylpurine DNA glycosylase

0.73	GO:0006284	base-excision repair
0.35	GO:0006307	DNA dealkylation involved in DNA repair

0.78	GO:0003905	alkylbase DNA N-glycosylase activity
0.55	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.39	GO:0042645	mitochondrial nucleoid
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.2.2.21

GO:0003905

sp|P23574|GBRG1_RAT
Gamma-aminobutyric acid receptor subunit gamma-1
Search

GABRG1

0.94	Gamma-aminobutyric acid receptor subunit epsilon

0.85	GO:0007214	gamma-aminobutyric acid signaling pathway
0.77	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.54	GO:0007268	chemical synaptic transmission
0.48	GO:0071420	cellular response to histamine
0.45	GO:0030534	adult behavior
0.43	GO:0009791	post-embryonic development

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.45	GO:0005254	chloride channel activity
0.39	GO:0050811	GABA receptor binding
0.35	GO:0008503	benzodiazepine receptor activity

0.56	GO:0005886	plasma membrane
0.47	GO:1902711	GABA-A receptor complex
0.44	GO:0030424	axon
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.38	GO:0030425	dendrite
0.38	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0060077	inhibitory synapse
0.35	GO:0031252	cell leading edge

sp|P23576|GBRA2_RAT
Gamma-aminobutyric acid receptor subunit alpha-2
Search

GABRA2

0.97	Gamma-aminobutyric acid receptor subunit alpha-2

0.85	GO:0007214	gamma-aminobutyric acid signaling pathway
0.77	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.43	GO:0060078	regulation of postsynaptic membrane potential
0.39	GO:0071420	cellular response to histamine
0.39	GO:0051932	synaptic transmission, GABAergic
0.37	GO:0006836	neurotransmitter transport
0.36	GO:0001505	regulation of neurotransmitter levels

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.47	GO:0099095	ligand-gated anion channel activity
0.45	GO:0005254	chloride channel activity
0.44	GO:0022835	transmitter-gated channel activity
0.43	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.41	GO:0008503	benzodiazepine receptor activity
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.56	GO:0005886	plasma membrane
0.54	GO:1902711	GABA-A receptor complex
0.54	GO:0060077	inhibitory synapse
0.51	GO:0098794	postsynapse
0.51	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.50	GO:0030424	axon
0.41	GO:0034707	chloride channel complex
0.40	GO:0030659	cytoplasmic vesicle membrane
0.40	GO:0030054	cell junction

sp|P23593|APOD_RAT
Apolipoprotein D
Search

APOD

0.86	Apolipoprotein D

0.75	GO:0007568	aging
0.69	GO:0006869	lipid transport
0.65	GO:0034443	negative regulation of lipoprotein oxidation
0.65	GO:0060587	regulation of lipoprotein lipid oxidation
0.64	GO:2000098	negative regulation of smooth muscle cell-matrix adhesion
0.64	GO:2000405	negative regulation of T cell migration
0.63	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.62	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.62	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.61	GO:0051895	negative regulation of focal adhesion assembly

0.68	GO:0008289	lipid binding
0.58	GO:0043178	alcohol binding
0.51	GO:0031409	pigment binding
0.38	GO:0097159	organic cyclic compound binding
0.37	GO:0005215	transporter activity
0.36	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.34	GO:0008242	omega peptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0050662	coenzyme binding

0.56	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005615	extracellular space
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.49	GO:0022626	cytosolic ribosome
0.46	GO:0005783	endoplasmic reticulum
0.37	GO:1903561	extracellular vesicle
0.35	GO:0044462	external encapsulating structure part
0.34	GO:0019867	outer membrane
0.34	GO:0030313	cell envelope

0.34

EC:1.3.99.3

GO:0003995

sp|P23606|TGM1_RAT
Protein-glutamine gamma-glutamyltransferase K
Search

TGM1

0.97	Glutamine gamma-glutamyltransferase K

0.84	GO:0018149	peptide cross-linking
0.61	GO:0010838	positive regulation of keratinocyte proliferation
0.58	GO:0030216	keratinocyte differentiation
0.55	GO:0045787	positive regulation of cell cycle
0.37	GO:0009887	animal organ morphogenesis
0.36	GO:0072378	blood coagulation, fibrin clot formation
0.35	GO:0043163	cell envelope organization
0.35	GO:0012501	programmed cell death
0.33	GO:0051262	protein tetramerization
0.33	GO:0098869	cellular oxidant detoxification

0.84	GO:0003810	protein-glutamine gamma-glutamyltransferase activity
0.36	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.33	GO:0004096	catalase activity
0.32	GO:0020037	heme binding
0.32	GO:0003677	DNA binding

0.38	GO:0005913	cell-cell adherens junction
0.38	GO:0070062	extracellular exosome
0.36	GO:0001533	cornified envelope
0.34	GO:0005737	cytoplasm
0.33	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0031012	extracellular matrix
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.84

EC:2.3.2.13

GO:0003810

sp|P23640|RB27A_RAT
Ras-related protein Rab-27A
Search

RAB27A

0.91	Putative rab subfamily protein of small gtpase

0.63	GO:0045921	positive regulation of exocytosis
0.61	GO:0032400	melanosome localization
0.60	GO:0097278	complement-dependent cytotoxicity
0.60	GO:1903433	regulation of constitutive secretory pathway
0.60	GO:0051904	pigment granule transport
0.59	GO:0071985	multivesicular body sorting pathway
0.58	GO:1990182	exosomal secretion
0.58	GO:0043316	cytotoxic T cell degranulation
0.57	GO:0036257	multivesicular body organization
0.57	GO:0043320	natural killer cell degranulation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.62	GO:0031489	myosin V binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019904	protein domain specific binding

0.64	GO:0032585	multivesicular body membrane
0.63	GO:0042470	melanosome
0.57	GO:0030133	transport vesicle
0.57	GO:0099503	secretory vesicle
0.54	GO:0001750	photoreceptor outer segment
0.53	GO:0030425	dendrite
0.53	GO:0005764	lysosome
0.52	GO:0005794	Golgi apparatus
0.49	GO:0030136	clathrin-coated vesicle
0.46	GO:0005798	Golgi-associated vesicle

sp|P23680|SAMP_RAT
Serum amyloid P-component
Search

0.83	Serum amyloid P-component

0.57	GO:0044870	modulation by host of viral glycoprotein metabolic process
0.57	GO:0052403	negative regulation by host of symbiont catalytic activity
0.57	GO:1903016	negative regulation of exo-alpha-sialidase activity
0.57	GO:0044867	modulation by host of viral catalytic activity
0.55	GO:0044793	negative regulation by host of viral process
0.55	GO:0045656	negative regulation of monocyte differentiation
0.55	GO:0046597	negative regulation of viral entry into host cell
0.55	GO:1903019	negative regulation of glycoprotein metabolic process
0.50	GO:0045087	innate immune response
0.40	GO:0006953	acute-phase response

0.57	GO:0001849	complement component C1q binding
0.56	GO:0046790	virion binding
0.53	GO:0046872	metal ion binding
0.49	GO:0042802	identical protein binding
0.39	GO:0030169	low-density lipoprotein particle binding
0.39	GO:0050750	low-density lipoprotein particle receptor binding
0.39	GO:0030246	carbohydrate binding
0.34	GO:0051082	unfolded protein binding
0.33	GO:0005044	scavenger receptor activity

0.65	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.34	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P23693|TNNI3_RAT
Troponin I, cardiac muscle
Search

TNNI3

0.89	High Mr cardiac troponin I

0.58	GO:0006941	striated muscle contraction
0.57	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions
0.56	GO:0060047	heart contraction
0.54	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.54	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.53	GO:0001570	vasculogenesis
0.51	GO:0050881	musculoskeletal movement
0.51	GO:0006874	cellular calcium ion homeostasis
0.50	GO:0032780	negative regulation of ATPase activity
0.40	GO:0006940	regulation of smooth muscle contraction

0.57	GO:0031014	troponin T binding
0.55	GO:0030172	troponin C binding
0.54	GO:0019855	calcium channel inhibitor activity
0.53	GO:0048306	calcium-dependent protein binding
0.51	GO:0003779	actin binding
0.49	GO:0019901	protein kinase binding
0.49	GO:0019904	protein domain specific binding
0.48	GO:0032403	protein complex binding
0.37	GO:0046872	metal ion binding
0.33	GO:0016887	ATPase activity

0.82	GO:0005861	troponin complex
0.54	GO:0097512	cardiac myofibril
0.35	GO:0005634	nucleus
0.34	GO:0005829	cytosol

0.33

GO:0016887

sp|P23711|HMOX2_RAT
Heme oxygenase 2
Search

HMOX2

0.58	Heme oxygenase

0.82	GO:0006788	heme oxidation
0.51	GO:0042167	heme catabolic process
0.46	GO:0055072	iron ion homeostasis
0.46	GO:0006979	response to oxidative stress
0.41	GO:0001666	response to hypoxia
0.39	GO:0002246	wound healing involved in inflammatory response
0.39	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron
0.39	GO:0071243	cellular response to arsenic-containing substance
0.39	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.39	GO:0072719	cellular response to cisplatin

0.82	GO:0004392	heme oxygenase (decyclizing) activity
0.47	GO:0046872	metal ion binding
0.42	GO:0020037	heme binding
0.37	GO:0042803	protein homodimerization activity
0.32	GO:0004871	signal transducer activity

0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0035579	specific granule membrane
0.35	GO:0005634	nucleus
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:1.14.99.3

GO:0004392

sp|P23739|SUIS_RAT
Sucrase-isomaltase, intestinal
Search

0.10	Sucrase-isomaltase, intestinal

0.60	GO:0005975	carbohydrate metabolic process
0.30	GO:0031667	response to nutrient levels
0.30	GO:0032868	response to insulin
0.30	GO:0048545	response to steroid hormone
0.30	GO:0009746	response to hexose
0.30	GO:0009744	response to sucrose
0.30	GO:0006950	response to stress
0.30	GO:0007568	aging

0.70	GO:0030246	carbohydrate binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.30	GO:0005515	protein binding

0.30	GO:0098590	plasma membrane region
0.30	GO:0005903	brush border
0.30	GO:0045177	apical part of cell
0.30	GO:0098589	membrane region
0.30	GO:1903561	extracellular vesicle
0.30	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:3.2.1

GO:0004553

sp|P23749|MRGRF_RAT
Mas-related G-protein coupled receptor member F
Search

MRGPRF

0.85	Beta-alanine receptor

0.71

GO:0007186

G-protein coupled receptor signaling pathway

0.72

GO:0004930

G-protein coupled receptor activity

0.44	GO:0031965	nuclear membrane
0.37	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P23764|GPX3_RAT
Glutathione peroxidase 3
Search

0.47	Epididymal secretory glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0051289	protein homotetramerization
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0042744	hydrogen peroxide catabolic process
0.43	GO:0033554	cellular response to stress
0.36	GO:0010269	response to selenium ion
0.36	GO:0051412	response to corticosterone
0.36	GO:0002238	response to molecule of fungal origin
0.35	GO:0006749	glutathione metabolic process

0.79	GO:0004602	glutathione peroxidase activity
0.53	GO:0008430	selenium binding
0.34	GO:0008134	transcription factor binding

0.54	GO:0005615	extracellular space
0.53	GO:0097524	sperm plasma membrane
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.79

EC:1.11.1.9

GO:0004602

sp|P23785|GRN_RAT
Granulins
Search

0.52	Granulin b

0.83	GO:0048675	axon extension
0.69	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.65	GO:0001889	liver development
0.30	GO:0061351	neural precursor cell proliferation
0.30	GO:0050679	positive regulation of epithelial cell proliferation
0.30	GO:0050769	positive regulation of neurogenesis
0.30	GO:0042221	response to chemical
0.30	GO:0006810	transport
0.30	GO:0007565	female pregnancy
0.30	GO:0001701	in utero embryonic development

0.30	GO:0005515	protein binding
0.30	GO:1901363	heterocyclic compound binding
0.30	GO:0030545	receptor regulator activity
0.30	GO:0097159	organic cyclic compound binding

0.46	GO:0005886	plasma membrane
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane
0.30	GO:0043230	extracellular organelle
0.30	GO:0043229	intracellular organelle
0.30	GO:0045202	synapse
0.30	GO:0005737	cytoplasm

sp|P23811|SCTR_RAT
Secretin receptor
Search

SCTR

0.97	Secretin receptor transcript variant 1

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0043950	positive regulation of cAMP-mediated signaling
0.37	GO:0007588	excretion
0.36	GO:0007420	brain development
0.36	GO:0007586	digestion

0.72	GO:0004930	G-protein coupled receptor activity
0.36	GO:0042277	peptide binding

0.63	GO:0005881	cytoplasmic microtubule
0.51	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P23897|GUC2C_RAT
Heat-stable enterotoxin receptor
Search

GUCY2C

0.57	Heat-stable enterotoxin receptor

0.78	GO:0006182	cGMP biosynthetic process
0.62	GO:0042127	regulation of cell proliferation
0.61	GO:0035556	intracellular signal transduction
0.59	GO:0006468	protein phosphorylation
0.56	GO:0009636	response to toxic substance
0.53	GO:0007168	receptor guanylyl cyclase signaling pathway
0.51	GO:0007586	digestion

0.78	GO:0004383	guanylate cyclase activity
0.69	GO:0004016	adenylate cyclase activity
0.67	GO:0015643	toxic substance binding
0.61	GO:0032550	purine ribonucleoside binding
0.61	GO:0019001	guanyl nucleotide binding
0.60	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005515	protein binding

0.75	GO:0008074	guanylate cyclase complex, soluble
0.67	GO:0005789	endoplasmic reticulum membrane
0.52	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

GO:0004383

sp|P23899|HNF1B_RAT
Hepatocyte nuclear factor 1-beta
Search

HNF1B

0.95	Hepatocyte nuclear factor 1-beta-A

0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.59	GO:0035565	regulation of pronephros size
0.59	GO:0061296	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
0.58	GO:0072181	mesonephric duct formation
0.58	GO:1900211	regulation of mesenchymal cell apoptotic process involved in metanephros development
0.58	GO:0039020	pronephric nephron tubule development
0.58	GO:0061017	hepatoblast differentiation
0.57	GO:0072095	regulation of branch elongation involved in ureteric bud branching
0.57	GO:0060677	ureteric bud elongation
0.57	GO:0072217	negative regulation of metanephros development

0.55	GO:0003677	DNA binding
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.38	GO:0032403	protein complex binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P23928|CRYAB_RAT
Alpha-crystallin B chain
Search

CRYAB

0.96	Alpha-crystallin B chain

0.62	GO:1905907	negative regulation of amyloid fibril formation
0.61	GO:0032463	negative regulation of protein homooligomerization
0.60	GO:0060561	apoptotic process involved in morphogenesis
0.59	GO:0071480	cellular response to gamma radiation
0.59	GO:0032387	negative regulation of intracellular transport
0.58	GO:0002088	lens development in camera-type eye
0.58	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:0007021	tubulin complex assembly
0.57	GO:0042542	response to hydrogen peroxide
0.57	GO:0001666	response to hypoxia

0.83	GO:0005212	structural constituent of eye lens
0.59	GO:0001540	amyloid-beta binding
0.55	GO:0042803	protein homodimerization activity
0.53	GO:0032403	protein complex binding
0.51	GO:0051082	unfolded protein binding
0.39	GO:0008017	microtubule binding
0.38	GO:0046872	metal ion binding
0.36	GO:0008426	protein kinase C inhibitor activity
0.35	GO:0005080	protein kinase C binding
0.35	GO:0044183	protein binding involved in protein folding

0.58	GO:0030018	Z disc
0.57	GO:0043209	myelin sheath
0.50	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.46	GO:0005739	mitochondrion
0.43	GO:0005886	plasma membrane
0.42	GO:0097512	cardiac myofibril
0.41	GO:0031430	M band
0.41	GO:0043204	perikaryon
0.41	GO:0043197	dendritic spine

0.33

EC:2.4

GO:0016757

sp|P23943|EDN2_RAT
Endothelin-2
Search

EDN2

0.96	Endothelin-2

0.85	GO:0019229	regulation of vasoconstriction
0.79	GO:0042310	vasoconstriction
0.69	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity
0.68	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.67	GO:0014820	tonic smooth muscle contraction
0.66	GO:0014821	phasic smooth muscle contraction
0.66	GO:0010460	positive regulation of heart rate
0.65	GO:0046457	prostanoid biosynthetic process
0.64	GO:0006693	prostaglandin metabolic process
0.64	GO:0051353	positive regulation of oxidoreductase activity

0.69	GO:0031708	endothelin B receptor binding
0.60	GO:0005179	hormone activity
0.49	GO:0031707	endothelin A receptor binding
0.44	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.39	GO:0005622	intracellular
0.37	GO:0045178	basal part of cell
0.35	GO:0031982	vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

0.64

GO:0051353

sp|P23944|ADA1D_RAT
Alpha-1D adrenergic receptor
Search

ADRA1D

0.84	LOW QUALITY PROTEIN: alpha-1D adrenergic receptor

0.82	GO:0071875	adrenergic receptor signaling pathway
0.65	GO:0019229	regulation of vasoconstriction
0.64	GO:0055117	regulation of cardiac muscle contraction
0.50	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
0.48	GO:0045987	positive regulation of smooth muscle contraction
0.47	GO:1903524	positive regulation of blood circulation
0.47	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.47	GO:0001983	baroreceptor response to increased systemic arterial blood pressure
0.45	GO:0045822	negative regulation of heart contraction
0.45	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway

0.85	GO:0004937	alpha1-adrenergic receptor activity
0.39	GO:0046982	protein heterodimerization activity

0.53	GO:0005886	plasma membrane
0.40	GO:0031965	nuclear membrane
0.38	GO:0030018	Z disc
0.38	GO:0045121	membrane raft
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P23965|ECI1_RAT
Enoyl-CoA delta isomerase 1, mitochondrial
Search

ECI1

0.90	Enoyl-CoA delta isomerase 1, mitochondrial

0.51

GO:0006635

fatty acid beta-oxidation

0.55	GO:0016853	isomerase activity
0.45	GO:0004300	enoyl-CoA hydratase activity
0.34	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding

0.44	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0070013	intracellular organelle lumen

0.55

EC:5

GO:0016853

sp|P23977|SC6A3_RAT
Sodium-dependent dopamine transporter
Search

SLC6A3

0.65	Solute carrier family 6 (neurotransmitter transporter), member 3

0.78	GO:0051937	catecholamine transport
0.76	GO:0006836	neurotransmitter transport
0.64	GO:0015696	ammonium transport
0.64	GO:0042420	dopamine catabolic process
0.63	GO:0060134	prepulse inhibition
0.63	GO:0042416	dopamine biosynthetic process
0.63	GO:0042053	regulation of dopamine metabolic process
0.63	GO:0021984	adenohypophysis development
0.62	GO:0007595	lactation
0.62	GO:0042220	response to cocaine

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.77	GO:0008504	monoamine transmembrane transporter activity
0.69	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.65	GO:0008519	ammonium transmembrane transporter activity
0.63	GO:0035240	dopamine binding
0.61	GO:0015238	drug transmembrane transporter activity
0.60	GO:0047485	protein N-terminus binding
0.45	GO:0043014	alpha-tubulin binding
0.45	GO:0048487	beta-tubulin binding

0.63	GO:0016600	flotillin complex
0.62	GO:0043005	neuron projection
0.59	GO:0005887	integral component of plasma membrane
0.58	GO:0043025	neuronal cell body
0.58	GO:0009986	cell surface
0.56	GO:0098793	presynapse

sp|P23978|SC6A1_RAT
Sodium- and chloride-dependent GABA transporter 1
Search

SLC6A1

0.58	Sodium- and chloride-dependent GABA transporter 1

0.85	GO:0015812	gamma-aminobutyric acid transport
0.66	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.66	GO:0014054	positive regulation of gamma-aminobutyric acid secretion
0.65	GO:0010288	response to lead ion
0.63	GO:0042220	response to cocaine
0.62	GO:0009744	response to sucrose
0.62	GO:0032355	response to estradiol
0.61	GO:0043090	amino acid import
0.61	GO:0051592	response to calcium ion
0.60	GO:0007612	learning

0.86	GO:0005332	gamma-aminobutyric acid:sodium symporter activity
0.43	GO:0046872	metal ion binding
0.41	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.65	GO:0030424	axon
0.55	GO:0009986	cell surface

sp|P23999|MYCS_RAT
Protein S-Myc
Search

MYCN

0.83	MYCN proto-oncogene, bHLH transcription factor

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0045607	regulation of inner ear auditory receptor cell differentiation
0.52	GO:0048712	negative regulation of astrocyte differentiation
0.52	GO:0002053	positive regulation of mesenchymal cell proliferation
0.52	GO:0001502	cartilage condensation
0.51	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.51	GO:0042733	embryonic digit morphogenesis
0.50	GO:0048754	branching morphogenesis of an epithelial tube

0.67	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0019900	kinase binding
0.38	GO:0032403	protein complex binding
0.36	GO:0071074	eukaryotic initiation factor eIF2 binding
0.35	GO:0070491	repressing transcription factor binding
0.35	GO:0033613	activating transcription factor binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0003729	mRNA binding

0.61	GO:0005634	nucleus
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0030424	axon
0.33	GO:0005739	mitochondrion
0.33	GO:0031975	envelope
0.33	GO:0043234	protein complex

sp|P24008|S5A1_RAT
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Search

SRD5A1

0.94	Steroid-5-alpha-reductase alpha polypeptide 1

0.69	GO:0008202	steroid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0030540	female genitalia development
0.48	GO:0030539	male genitalia development
0.46	GO:0034754	cellular hormone metabolic process
0.46	GO:0042446	hormone biosynthetic process
0.43	GO:0042180	cellular ketone metabolic process
0.43	GO:0008610	lipid biosynthetic process
0.41	GO:0042747	circadian sleep/wake cycle, REM sleep
0.40	GO:0071394	cellular response to testosterone stimulus

0.79	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity
0.43	GO:0047751	cholestenone 5-alpha-reductase activity
0.38	GO:0070402	NADPH binding
0.37	GO:0033218	amide binding
0.33	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity
0.33	GO:0008519	ammonium transmembrane transporter activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0016779	nucleotidyltransferase activity
0.32	GO:0003723	RNA binding

0.49	GO:0005737	cytoplasm
0.40	GO:0070852	cell body fiber
0.39	GO:0043209	myelin sheath
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0043025	neuronal cell body
0.38	GO:0031984	organelle subcompartment
0.36	GO:0031090	organelle membrane
0.36	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0035770	ribonucleoprotein granule
0.32	GO:0031974	membrane-enclosed lumen

0.79	EC:1.3.99.5	GO:0003865
0.43	KEGG:R02610	GO:0047751

sp|P24049|RL17_RAT
60S ribosomal protein L17
Search

RPL17

0.64	W-linked ribosomal protein L17

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.37	GO:1990928	response to amino acid starvation
0.36	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.36	GO:0034198	cellular response to amino acid starvation
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.35	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0070180	large ribosomal subunit rRNA binding
0.35	GO:0005515	protein binding

0.70	GO:0015934	large ribosomal subunit
0.37	GO:0022626	cytosolic ribosome
0.36	GO:0031672	A band
0.36	GO:0005844	polysome
0.35	GO:0005634	nucleus

sp|P24050|RS5_RAT
40S ribosomal protein S5
Search

RPS5

0.73	Ribosomal protein S5

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.46	GO:0006450	regulation of translational fidelity
0.45	GO:0000028	ribosomal small subunit assembly
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.62	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.67	GO:0015935	small ribosomal subunit
0.50	GO:0022626	cytosolic ribosome
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P24051|RS27L_RAT
40S ribosomal protein S27-like
Search

0.70	40S ribosomal protein S27

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0000028	ribosomal small subunit assembly
0.47	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.47	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.46	GO:0031571	mitotic G1 DNA damage checkpoint
0.46	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0045727	positive regulation of translation

0.64	GO:0003735	structural constituent of ribosome
0.54	GO:0046872	metal ion binding
0.48	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.47	GO:0008494	translation activator activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.42	GO:0005634	nucleus
0.40	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|P24053|NMBR_RAT
Neuromedin-B receptor
Search

NMBR

0.97	Neuromedin-B receptor

0.82	GO:0031989	bombesin receptor signaling pathway
0.41	GO:0036343	psychomotor behavior
0.41	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.40	GO:0035176	social behavior
0.40	GO:0007218	neuropeptide signaling pathway
0.38	GO:0042127	regulation of cell proliferation
0.37	GO:0043207	response to external biotic stimulus

0.82

GO:0004946

bombesin receptor activity

0.48	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P24054|SPRL1_RAT
SPARC-like protein 1
Search

SPARCL1

0.97	Proliferation-inducing protein 33

0.60	GO:0007165	signal transduction
0.43	GO:0048856	anatomical structure development
0.38	GO:0001937	negative regulation of endothelial cell proliferation
0.37	GO:0010595	positive regulation of endothelial cell migration
0.37	GO:0016525	negative regulation of angiogenesis
0.37	GO:0034101	erythrocyte homeostasis
0.37	GO:0032501	multicellular organismal process
0.37	GO:0043473	pigmentation
0.36	GO:0071363	cellular response to growth factor stimulus
0.35	GO:0022604	regulation of cell morphogenesis

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0005518	collagen binding
0.70	GO:0005509	calcium ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.73	GO:0005615	extracellular space
0.38	GO:0031092	platelet alpha granule membrane
0.37	GO:1903561	extracellular vesicle
0.37	GO:0016363	nuclear matrix
0.36	GO:0009986	cell surface
0.36	GO:0045202	synapse
0.35	GO:0044420	extracellular matrix component
0.34	GO:0005788	endoplasmic reticulum lumen

sp|P24062|IGF1R_RAT
Insulin-like growth factor 1 receptor
Search

IGF1R

0.67	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.72	GO:0046777	protein autophosphorylation
0.57	GO:0051389	inactivation of MAPKK activity
0.57	GO:0097242	amyloid-beta clearance
0.55	GO:1904646	cellular response to amyloid-beta
0.54	GO:0045740	positive regulation of DNA replication
0.53	GO:0046328	regulation of JNK cascade
0.52	GO:0043066	negative regulation of apoptotic process
0.52	GO:0051262	protein tetramerization

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.80	GO:0043560	insulin receptor substrate binding
0.78	GO:0043548	phosphatidylinositol 3-kinase binding
0.62	GO:0005520	insulin-like growth factor binding
0.57	GO:0043559	insulin binding
0.55	GO:0005158	insulin receptor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding

0.57	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.51	GO:0043235	receptor complex
0.41	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0030315	T-tubule
0.35	GO:0005901	caveola
0.35	GO:0043025	neuronal cell body
0.35	GO:0030424	axon
0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005737	cytoplasm

0.80

GO:0004714

sp|P24090|FETUA_RAT
Alpha-2-HS-glycoprotein
Search

AHSG

0.97

Fetuin-A

0.76	GO:0010951	negative regulation of endopeptidase activity
0.68	GO:0070168	negative regulation of biomineral tissue development
0.66	GO:0006953	acute-phase response
0.66	GO:0050766	positive regulation of phagocytosis
0.65	GO:0030279	negative regulation of ossification
0.65	GO:0030500	regulation of bone mineralization
0.62	GO:0050727	regulation of inflammatory response
0.62	GO:0001503	ossification
0.40	GO:0046627	negative regulation of insulin receptor signaling pathway
0.38	GO:0046852	positive regulation of bone remodeling

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.39	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity
0.35	GO:0005515	protein binding

0.71	GO:0005615	extracellular space
0.58	GO:0031012	extracellular matrix
0.54	GO:0005794	Golgi apparatus
0.41	GO:0043230	extracellular organelle
0.39	GO:0031982	vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0043234	protein complex
0.34	GO:0005886	plasma membrane

sp|P24135|PLCG2_RAT
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Search

PLCG2

0.53	Phosphoinositide phospholipase C

0.77	GO:0009395	phospholipid catabolic process
0.62	GO:0002316	follicular B cell differentiation
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0032959	inositol trisphosphate biosynthetic process
0.59	GO:0032237	activation of store-operated calcium channel activity
0.59	GO:0002092	positive regulation of receptor internalization
0.58	GO:0050852	T cell receptor signaling pathway
0.57	GO:0032481	positive regulation of type I interferon production
0.57	GO:0051209	release of sequestered calcium ion into cytosol
0.57	GO:0050853	B cell receptor signaling pathway

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.63	GO:0004871	signal transducer activity
0.57	GO:0001784	phosphotyrosine residue binding
0.40	GO:0005509	calcium ion binding

0.49	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

sp|P24155|THOP1_RAT
Thimet oligopeptidase
Search

THOP1

0.91	Thimet oligopeptidase

0.57	GO:0006508	proteolysis
0.39	GO:0006518	peptide metabolic process
0.35	GO:0000209	protein polyubiquitination
0.34	GO:0035556	intracellular signal transduction

0.65	GO:0004222	metalloendopeptidase activity
0.51	GO:0046872	metal ion binding
0.38	GO:0042277	peptide binding
0.35	GO:0005515	protein binding

0.45	GO:0005758	mitochondrial intermembrane space
0.34	GO:0005829	cytosol

0.65

GO:0004222

sp|P24268|CATD_RAT
Cathepsin D
Search

CTSD

0.86	Cathepsin D preproprotein (Predicted)

0.60	GO:0006508	proteolysis
0.44	GO:0003406	retinal pigment epithelium development
0.42	GO:0006914	autophagy
0.42	GO:0061061	muscle structure development
0.41	GO:0009617	response to bacterium
0.40	GO:0030163	protein catabolic process
0.38	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.37	GO:0007033	vacuole organization
0.36	GO:0070925	organelle assembly
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

0.69	GO:0070001	aspartic-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.35	GO:0042277	peptide binding
0.34	GO:0008234	cysteine-type peptidase activity
0.34	GO:0017171	serine hydrolase activity
0.33	GO:0005515	protein binding

0.74	GO:0005764	lysosome
0.43	GO:0042470	melanosome
0.41	GO:0005615	extracellular space
0.39	GO:0045121	membrane raft
0.38	GO:0031012	extracellular matrix
0.37	GO:1903561	extracellular vesicle
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0005775	vacuolar lumen

0.34

GO:0008234

sp|P24329|THTR_RAT
Thiosulfate sulfurtransferase
Search

TST

0.51	Thiosulfate sulfurtransferase

0.61	GO:0035928	rRNA import into mitochondrion
0.54	GO:0030855	epithelial cell differentiation
0.36	GO:0009440	cyanate catabolic process
0.34	GO:0016226	iron-sulfur cluster assembly
0.34	GO:0019221	cytokine-mediated signaling pathway
0.32	GO:0006508	proteolysis

0.78	GO:0004792	thiosulfate sulfurtransferase activity
0.54	GO:0008097	5S rRNA binding
0.34	GO:0004896	cytokine receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity

0.46	GO:0044429	mitochondrial part
0.46	GO:0019866	organelle inner membrane
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:2.8.1.1	GO:0004792
0.78	KEGG:R01931	GO:0004792

sp|P24338|AREG_RAT
Amphiregulin
Search

AREG

0.97	Amphiregulin short form

0.69	GO:0060598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
0.67	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation
0.67	GO:0060744	mammary gland branching involved in thelarche
0.65	GO:0007173	epidermal growth factor receptor signaling pathway
0.65	GO:0032355	response to estradiol
0.65	GO:0060749	mammary gland alveolus development
0.64	GO:0045740	positive regulation of DNA replication
0.63	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.61	GO:0008284	positive regulation of cell proliferation
0.55	GO:0007186	G-protein coupled receptor signaling pathway

0.54	GO:0005154	epidermal growth factor receptor binding
0.50	GO:0008083	growth factor activity
0.42	GO:0005125	cytokine activity

0.58	GO:0009986	cell surface
0.57	GO:0005615	extracellular space
0.49	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.36	GO:0012506	vesicle membrane
0.36	GO:0097708	intracellular vesicle
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment

sp|P24368|PPIB_RAT
Peptidyl-prolyl cis-trans isomerase B
Search

PPIB

0.48	Peptidyl-prolyl cis-trans isomerase B

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.56	GO:0044829	positive regulation by host of viral genome replication
0.54	GO:0040018	positive regulation of multicellular organism growth
0.53	GO:0060348	bone development
0.52	GO:0050821	protein stabilization
0.37	GO:1901873	regulation of post-translational protein modification
0.34	GO:0051169	nuclear transport

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.50	GO:0070063	RNA polymerase binding
0.49	GO:0032403	protein complex binding
0.34	GO:0003723	RNA binding
0.34	GO:0051082	unfolded protein binding
0.32	GO:0046872	metal ion binding

0.55	GO:0034663	endoplasmic reticulum chaperone complex
0.51	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005634	nucleus
0.40	GO:0005788	endoplasmic reticulum lumen
0.40	GO:0042470	melanosome
0.40	GO:0005790	smooth endoplasmic reticulum
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.72

EC:5.2.1.8

GO:0003755

sp|P24388|CRHBP_RAT
Corticotropin-releasing factor-binding protein
Search

CRHBP

0.96	Corticotropin releasing hormone binding protein (Fragment)

0.63	GO:1900010	regulation of corticotropin-releasing hormone receptor activity
0.63	GO:0051460	negative regulation of corticotropin secretion
0.62	GO:0002125	maternal aggressive behavior
0.62	GO:0035865	cellular response to potassium ion
0.60	GO:0097211	cellular response to gonadotropin-releasing hormone
0.60	GO:0071392	cellular response to estradiol stimulus
0.60	GO:2000310	regulation of NMDA receptor activity
0.60	GO:0001963	synaptic transmission, dopaminergic
0.60	GO:0071391	cellular response to estrogen stimulus
0.59	GO:0048149	behavioral response to ethanol

0.86	GO:0051424	corticotropin-releasing hormone binding
0.33	GO:0005515	protein binding

0.62	GO:0005576	extracellular region
0.56	GO:0030141	secretory granule
0.46	GO:0005634	nucleus
0.42	GO:0043196	varicosity
0.41	GO:0005767	secondary lysosome
0.41	GO:0005771	multivesicular body
0.40	GO:0043204	perikaryon
0.40	GO:0043679	axon terminus
0.40	GO:0030425	dendrite
0.38	GO:0005874	microtubule

sp|P24389|IOD1_RAT
Type I iodothyronine deiodinase
Search

DIO1

0.75	Type I iodothyronine deiodinase

0.78	GO:0042446	hormone biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.40	GO:0061074	regulation of neural retina development
0.37	GO:0006590	thyroid hormone generation
0.35	GO:0045454	cell redox homeostasis
0.34	GO:0006091	generation of precursor metabolites and energy

0.85	GO:0004800	thyroxine 5'-deiodinase activity
0.41	GO:0008430	selenium binding

0.45	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:1.97.1.10

GO:0004800

sp|P24392|PEX2_RAT
Peroxisome biogenesis factor 2
Search

PEX2

0.83	Peroxisomal biogenesis factor 2

0.59	GO:0048147	negative regulation of fibroblast proliferation
0.58	GO:0031648	protein destabilization
0.57	GO:0050680	negative regulation of epithelial cell proliferation
0.57	GO:0000038	very long-chain fatty acid metabolic process
0.56	GO:0016558	protein import into peroxisome matrix
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0006635	fatty acid beta-oxidation
0.38	GO:0045540	regulation of cholesterol biosynthetic process
0.38	GO:0006699	bile acid biosynthetic process
0.38	GO:0042632	cholesterol homeostasis

0.53	GO:0046872	metal ion binding
0.38	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity
0.33	GO:0005515	protein binding
0.32	GO:0051538	3 iron, 4 sulfur cluster binding
0.32	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.32	GO:0051537	2 iron, 2 sulfur cluster binding
0.32	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0009055	electron transfer activity

0.55	GO:0016593	Cdc73/Paf1 complex
0.55	GO:0005779	integral component of peroxisomal membrane
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane

0.35	EC:6	GO:0016874
0.32	KEGG:R02164	GO:0008177

sp|P24393|GRP_RAT
Gastrin-releasing peptide
Search

GRP

0.97	Gastrin-releasing peptide

0.80	GO:0007218	neuropeptide signaling pathway
0.74	GO:0010469	regulation of receptor activity
0.74	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
0.71	GO:0036343	psychomotor behavior
0.67	GO:0035176	social behavior
0.56	GO:0043207	response to external biotic stimulus
0.52	GO:0090277	positive regulation of peptide hormone secretion
0.37	GO:0048565	digestive tract development

0.83

GO:0005184

neuropeptide hormone activity

0.61	GO:0005615	extracellular space
0.53	GO:0034774	secretory granule lumen

sp|P24464|CP4AC_RAT
Cytochrome P450 4A12
Search

0.97	Fatty acid omega-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0006690	icosanoid metabolic process
0.45	GO:0033559	unsaturated fatty acid metabolic process
0.44	GO:0001676	long-chain fatty acid metabolic process
0.41	GO:0048252	lauric acid metabolic process
0.41	GO:1901569	fatty acid derivative catabolic process
0.40	GO:0009062	fatty acid catabolic process
0.39	GO:1901616	organic hydroxy compound catabolic process
0.39	GO:0001822	kidney development
0.38	GO:0003095	pressure natriuresis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0103002	16-hydroxypalmitate dehydrogenase activity
0.35	GO:0050544	arachidonic acid binding
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0016324	apical plasma membrane
0.40	GO:0005615	extracellular space
0.39	GO:0031090	organelle membrane
0.35	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P24470|CP2CN_RAT
Cytochrome P450 2C23
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.61	GO:0042738	exogenous drug catabolic process
0.59	GO:0016098	monoterpenoid metabolic process
0.55	GO:0019373	epoxygenase P450 pathway
0.54	GO:0008202	steroid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0070988	demethylation
0.45	GO:0019627	urea metabolic process
0.45	GO:0002933	lipid hydroxylation
0.36	GO:0046483	heterocycle metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.59	GO:0034875	caffeine oxidase activity
0.43	GO:0019899	enzyme binding
0.39	GO:0008144	drug binding

0.40	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P24473|GSTK1_RAT
Glutathione S-transferase kappa 1
Search

GSTK1

0.68	Glutathione S-transferase kappa

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0030855	epithelial cell differentiation
0.48	GO:0006749	glutathione metabolic process
0.46	GO:0098869	cellular oxidant detoxification
0.36	GO:1901687	glutathione derivative biosynthetic process
0.33	GO:0006468	protein phosphorylation

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.72	GO:0004364	glutathione transferase activity
0.51	GO:0004602	glutathione peroxidase activity
0.47	GO:0005102	receptor binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0018845	2-hydroxychromene-2-carboxylate isomerase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005777	peroxisome
0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.37	GO:0005759	mitochondrial matrix
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.72	EC:2.5.1.18	GO:0004364
0.32	KEGG:R05137	GO:0018845

sp|P24483|ADX_RAT
Adrenodoxin, mitochondrial
Search

FDX1

0.61	Adrenodoxin, mitochondrial

0.61	GO:0022900	electron transport chain
0.56	GO:1904321	response to forskolin
0.54	GO:0071320	cellular response to cAMP
0.53	GO:1901655	cellular response to ketone
0.53	GO:0008203	cholesterol metabolic process
0.52	GO:0035690	cellular response to drug
0.51	GO:0042446	hormone biosynthetic process
0.50	GO:0071396	cellular response to lipid
0.43	GO:1904087	negative regulation of epiboly involved in gastrulation with mouth forming second
0.42	GO:0006694	steroid biosynthetic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.36	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.36	GO:0015039	NADPH-adrenodoxin reductase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0019899	enzyme binding
0.34	GO:0042803	protein homodimerization activity

0.44	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0044425	membrane part

0.36

EC:1.14.15.6

GO:0008386

sp|P24485|CD53_RAT
Leukocyte surface antigen CD53
Search

CD53

0.53	Tetraspanin

0.58	GO:1901741	positive regulation of myoblast fusion
0.46	GO:0007166	cell surface receptor signaling pathway
0.39	GO:0006461	protein complex assembly
0.38	GO:0045661	regulation of myoblast differentiation
0.37	GO:0007283	spermatogenesis
0.37	GO:0098609	cell-cell adhesion
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0040008	regulation of growth
0.34	GO:1900047	negative regulation of hemostasis
0.34	GO:0050819	negative regulation of coagulation

0.43	GO:0005178	integrin binding
0.42	GO:0003823	antigen binding

0.57	GO:0001772	immunological synapse
0.52	GO:0005911	cell-cell junction
0.45	GO:0005887	integral component of plasma membrane
0.42	GO:0097197	tetraspanin-enriched microdomain
0.41	GO:0031982	vesicle
0.41	GO:0009986	cell surface
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.35	GO:0005925	focal adhesion
0.34	GO:0098805	whole membrane

sp|P24524|GLRA3_RAT
Glycine receptor subunit alpha-3
Search

GLRA3

0.90	Glycine receptor subunit alpha-3

0.68	GO:0060079	excitatory postsynaptic potential
0.66	GO:1902476	chloride transmembrane transport
0.51	GO:0051260	protein homooligomerization
0.51	GO:0060012	synaptic transmission, glycinergic
0.49	GO:0043200	response to amino acid
0.48	GO:0007218	neuropeptide signaling pathway
0.41	GO:0071294	cellular response to zinc ion
0.41	GO:0071361	cellular response to ethanol
0.39	GO:0071229	cellular response to acid chemical
0.39	GO:0071417	cellular response to organonitrogen compound

0.85	GO:0016594	glycine binding
0.75	GO:0022824	transmitter-gated ion channel activity
0.75	GO:0016934	extracellularly glycine-gated chloride channel activity
0.69	GO:0099600	transmembrane receptor activity
0.39	GO:0043210	alkanesulfonate binding
0.35	GO:0046872	metal ion binding

0.67	GO:0098794	postsynapse
0.66	GO:0097060	synaptic membrane
0.66	GO:0005887	integral component of plasma membrane
0.53	GO:0034707	chloride channel complex
0.40	GO:0043025	neuronal cell body
0.39	GO:0043005	neuron projection
0.38	GO:0098978	glutamatergic synapse
0.38	GO:0098982	GABA-ergic synapse
0.38	GO:0060077	inhibitory synapse
0.37	GO:0009897	external side of plasma membrane

sp|P24528|MGMT_RAT
Methylated-DNA--protein-cysteine methyltransferase
Search

MGMT

0.45	Methylated-DNA--protein-cysteine methyltransferase

0.65	GO:0006281	DNA repair
0.63	GO:0032259	methylation
0.53	GO:2000781	positive regulation of double-strand break repair
0.52	GO:0035510	DNA dealkylation
0.51	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.49	GO:0060548	negative regulation of cell death
0.43	GO:0051593	response to folic acid
0.43	GO:0060644	mammary gland epithelial cell differentiation
0.42	GO:0071479	cellular response to ionizing radiation
0.42	GO:0045471	response to ethanol

0.78	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity
0.38	GO:0005509	calcium ion binding
0.38	GO:0003677	DNA binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0008270	zinc ion binding
0.35	GO:0009008	DNA-methyltransferase activity
0.33	GO:0015095	magnesium ion transmembrane transporter activity
0.32	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0030145	manganese ion binding
0.32	GO:0015197	peptide transporter activity

0.46	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.1.1.63

GO:0003908

sp|P24587|AKAP5_RAT
A-kinase anchor protein 5
Search

AKAP5

0.69	A-kinase anchor protein 5

0.70	GO:0006605	protein targeting
0.70	GO:0036394	amylase secretion
0.63	GO:0010738	regulation of protein kinase A signaling
0.62	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.55	GO:0014850	response to muscle activity
0.55	GO:0045762	positive regulation of adenylate cyclase activity
0.55	GO:0051602	response to electrical stimulus
0.55	GO:0043267	negative regulation of potassium ion transport
0.55	GO:0050775	positive regulation of dendrite morphogenesis
0.54	GO:0007194	negative regulation of adenylate cyclase activity

0.69	GO:0008179	adenylate cyclase binding
0.66	GO:0030346	protein phosphatase 2B binding
0.64	GO:0035254	glutamate receptor binding
0.64	GO:0034237	protein kinase A regulatory subunit binding
0.63	GO:0097110	scaffold protein binding
0.59	GO:0017124	SH3 domain binding
0.57	GO:0005516	calmodulin binding
0.57	GO:0031698	beta-2 adrenergic receptor binding
0.55	GO:0050811	GABA receptor binding
0.52	GO:0045296	cadherin binding

0.56	GO:0032591	dendritic spine membrane
0.55	GO:0031527	filopodium membrane
0.54	GO:0060076	excitatory synapse
0.54	GO:0043198	dendritic shaft
0.52	GO:0014069	postsynaptic density
0.52	GO:0016323	basolateral plasma membrane
0.52	GO:0005856	cytoskeleton
0.51	GO:0043025	neuronal cell body
0.51	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0043234	protein complex

sp|P24594|IBP5_RAT
Insulin-like growth factor-binding protein 5
Search

IGFBP5

0.95	Insulin like growth factor binding protein 5

0.74	GO:0001558	regulation of cell growth
0.63	GO:0060416	response to growth hormone
0.61	GO:1904205	negative regulation of skeletal muscle hypertrophy
0.61	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.59	GO:0044342	type B pancreatic cell proliferation
0.59	GO:0060056	mammary gland involution
0.58	GO:0014912	negative regulation of smooth muscle cell migration
0.57	GO:0048286	lung alveolus development
0.57	GO:0045668	negative regulation of osteoblast differentiation
0.57	GO:1901862	negative regulation of muscle tissue development

0.84	GO:0005520	insulin-like growth factor binding
0.61	GO:0001968	fibronectin binding

0.66	GO:0005576	extracellular region
0.59	GO:0036454	growth factor complex
0.35	GO:0005788	endoplasmic reticulum lumen

sp|P24623|CRYAA_RAT
Alpha-crystallin A chain
Search

CRYAA

0.95	Alpha-crystallin A chain

0.58	GO:0070309	lens fiber cell morphogenesis
0.58	GO:0070141	response to UV-A
0.57	GO:0060561	apoptotic process involved in morphogenesis
0.57	GO:0048596	embryonic camera-type eye morphogenesis
0.55	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.55	GO:0007021	tubulin complex assembly
0.55	GO:0042542	response to hydrogen peroxide
0.55	GO:0030307	positive regulation of cell growth
0.54	GO:0001666	response to hypoxia
0.52	GO:0001934	positive regulation of protein phosphorylation

0.85	GO:0005212	structural constituent of eye lens
0.44	GO:0046872	metal ion binding
0.39	GO:0042802	identical protein binding
0.39	GO:0051082	unfolded protein binding

0.47	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.38	GO:0070062	extracellular exosome
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part

sp|P24800|PR6A1_RAT
Prolactin-6A1
Search

0.92	Prolactin family 6, subfamily a, member 1

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.43	GO:0016525	negative regulation of angiogenesis

0.79	GO:0005179	hormone activity
0.42	GO:0005125	cytokine activity

0.66

GO:0005576

extracellular region

sp|P24898|JUNB_RAT
Transcription factor jun-B
Search

0.93	Transcription factor jun-B

0.69	GO:0051726	regulation of cell cycle
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0033687	osteoblast proliferation
0.62	GO:0071277	cellular response to calcium ion
0.62	GO:0060136	embryonic process involved in female pregnancy
0.61	GO:0002573	myeloid leukocyte differentiation
0.61	GO:0001944	vasculature development
0.60	GO:0001829	trophectodermal cell differentiation
0.60	GO:0046697	decidualization
0.59	GO:0060711	labyrinthine layer development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0003713	transcription coactivator activity
0.50	GO:0008134	transcription factor binding
0.45	GO:0070412	R-SMAD binding
0.44	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0003682	chromatin binding
0.42	GO:0005096	GTPase activator activity
0.42	GO:0042803	protein homodimerization activity

0.64	GO:0035976	transcription factor AP-1 complex
0.53	GO:0031981	nuclear lumen
0.50	GO:0000785	chromatin
0.43	GO:0017053	transcriptional repressor complex
0.35	GO:0005829	cytosol
0.32	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P24942|EAA1_RAT
Excitatory amino acid transporter 1
Search

SLC1A3

0.45	Amino acid transporter

0.60	GO:0140016	D-aspartate import across plasma membrane
0.60	GO:0140009	L-aspartate import across plasma membrane
0.59	GO:0009449	gamma-aminobutyric acid biosynthetic process
0.59	GO:0098712	L-glutamate import across plasma membrane
0.58	GO:0031223	auditory behavior
0.56	GO:0021545	cranial nerve development
0.56	GO:0050885	neuromuscular process controlling balance
0.55	GO:0050806	positive regulation of synaptic transmission
0.54	GO:0007605	sensory perception of sound
0.52	GO:0048667	cell morphogenesis involved in neuron differentiation

0.72	GO:0015293	symporter activity
0.58	GO:0016595	glutamate binding
0.55	GO:0005313	L-glutamate transmembrane transporter activity
0.51	GO:0015081	sodium ion transmembrane transporter activity
0.48	GO:0022853	active ion transmembrane transporter activity
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.53	GO:0043025	neuronal cell body
0.52	GO:0043005	neuron projection
0.51	GO:0009986	cell surface
0.47	GO:0005887	integral component of plasma membrane
0.35	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0016323	basolateral plasma membrane
0.34	GO:0098794	postsynapse
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005794	Golgi apparatus
0.33	GO:0019866	organelle inner membrane

sp|P25023|BKRB2_RAT
B2 bradykinin receptor
Search

BDKRB2

0.97	Bradykinin receptor, beta 2

0.82	GO:0006939	smooth muscle contraction
0.81	GO:0042310	vasoconstriction
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:1902238	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
0.62	GO:0006950	response to stress
0.61	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.60	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.59	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.59	GO:0042311	vasodilation
0.57	GO:0050482	arachidonic acid secretion

0.86	GO:0004947	bradykinin receptor activity
0.63	GO:0031702	type 1 angiotensin receptor binding
0.59	GO:0002020	protease binding
0.53	GO:0046982	protein heterodimerization activity
0.37	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0004982	N-formyl peptide receptor activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.35	GO:0005124	scavenger receptor binding
0.35	GO:0008188	neuropeptide receptor activity
0.34	GO:0042277	peptide binding

0.54	GO:0005768	endosome
0.44	GO:0005886	plasma membrane
0.33	GO:0005635	nuclear envelope
0.33	GO:0099513	polymeric cytoskeletal fiber
0.33	GO:0043005	neuron projection
0.32	GO:0015629	actin cytoskeleton
0.32	GO:0005794	Golgi apparatus
0.32	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0045111	intermediate filament cytoskeleton
0.32	GO:0005783	endoplasmic reticulum

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P25030|K1C20_RAT
Keratin, type I cytoskeletal 20
Search

0.91	Keratin, type I cytoskeletal 20

0.64	GO:0045104	intermediate filament cytoskeleton organization
0.55	GO:0042633	hair cycle
0.55	GO:0097435	supramolecular fiber organization
0.51	GO:0030855	epithelial cell differentiation
0.51	GO:0050708	regulation of protein secretion
0.51	GO:0009267	cellular response to starvation
0.50	GO:0007568	aging
0.47	GO:0043588	skin development
0.46	GO:0008544	epidermis development
0.44	GO:0002009	morphogenesis of an epithelium

0.62	GO:0005198	structural molecule activity
0.50	GO:1990254	keratin filament binding
0.44	GO:0032395	MHC class II receptor activity
0.43	GO:0042289	MHC class II protein binding

0.79	GO:0005882	intermediate filament
0.47	GO:0045178	basal part of cell
0.46	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.39	GO:0071944	cell periphery
0.37	GO:0070062	extracellular exosome

sp|P25031|REG3B_RAT
Regenerating islet-derived protein 3-beta
Search

0.97	Pancreatic beta cell growth factor

0.67	GO:0044278	cell wall disruption in other organism
0.63	GO:0045617	negative regulation of keratinocyte differentiation
0.63	GO:0010838	positive regulation of keratinocyte proliferation
0.62	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.61	GO:0050830	defense response to Gram-positive bacterium
0.60	GO:0090303	positive regulation of wound healing
0.59	GO:0050829	defense response to Gram-negative bacterium
0.59	GO:0051715	cytolysis in other organism
0.59	GO:0006953	acute-phase response
0.51	GO:0002755	MyD88-dependent toll-like receptor signaling pathway

0.62	GO:0070492	oligosaccharide binding
0.56	GO:0042834	peptidoglycan binding
0.54	GO:0042802	identical protein binding
0.43	GO:0008083	growth factor activity
0.41	GO:0019838	growth factor binding
0.40	GO:0019903	protein phosphatase binding
0.37	GO:0046983	protein dimerization activity
0.37	GO:2001065	mannan binding
0.35	GO:0008201	heparin binding
0.33	GO:0008270	zinc ion binding

0.53	GO:0030141	secretory granule
0.52	GO:0005576	extracellular region
0.42	GO:0044216	other organism cell
0.41	GO:0032809	neuronal cell body membrane
0.41	GO:0032590	dendrite membrane
0.41	GO:0045178	basal part of cell
0.41	GO:0045177	apical part of cell
0.40	GO:0030426	growth cone
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0043234	protein complex

sp|P25086|IL1RA_RAT
Interleukin-1 receptor antagonist protein
Search

IL1RN

0.81	Interleukin 1 receptor antagonist

0.80	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.64	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.62	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.59	GO:0030073	insulin secretion
0.59	GO:0051384	response to glucocorticoid
0.51	GO:0031649	heat generation
0.51	GO:0019221	cytokine-mediated signaling pathway
0.48	GO:1902714	negative regulation of interferon-gamma secretion

0.85	GO:0005149	interleukin-1 receptor binding
0.80	GO:0005125	cytokine activity
0.72	GO:0005152	interleukin-1 receptor antagonist activity

0.73	GO:0005615	extracellular space
0.51	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.33	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane

sp|P25093|FAAA_RAT
Fumarylacetoacetase
Search

FAH

0.49	Fumarylacetoacetate hydrolase

0.69	GO:0009072	aromatic amino acid family metabolic process
0.50	GO:0006527	arginine catabolic process
0.39	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.37	GO:0042737	drug catabolic process
0.36	GO:1901361	organic cyclic compound catabolic process
0.36	GO:0019439	aromatic compound catabolic process
0.34	GO:0006396	RNA processing
0.34	GO:0043066	negative regulation of apoptotic process
0.33	GO:0090501	RNA phosphodiester bond hydrolysis
0.33	GO:0001510	RNA methylation

0.83	GO:0004334	fumarylacetoacetase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0005515	protein binding
0.33	GO:0004518	nuclease activity
0.33	GO:0016829	lyase activity
0.33	GO:0008168	methyltransferase activity
0.32	GO:0003723	RNA binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.83	EC:3.7.1.2	GO:0004334
0.83	KEGG:R01364	GO:0004334

sp|P25094|PMP22_RAT
Peripheral myelin protein 22
Search

PMP22

0.97	Peripheral myelin protein 22

0.63	GO:0032060	bleb assembly
0.56	GO:0008219	cell death
0.47	GO:0016049	cell growth
0.44	GO:0003093	regulation of glomerular filtration
0.44	GO:0001913	T cell mediated cytotoxicity
0.44	GO:2001212	regulation of vasculogenesis
0.44	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.44	GO:0042127	regulation of cell proliferation
0.44	GO:0007566	embryo implantation
0.44	GO:0043534	blood vessel endothelial cell migration

0.42	GO:0005178	integrin binding
0.41	GO:0019901	protein kinase binding

0.44	GO:0005886	plasma membrane
0.42	GO:0045121	membrane raft
0.42	GO:0045177	apical part of cell
0.41	GO:0043218	compact myelin
0.41	GO:0009986	cell surface
0.40	GO:0031410	cytoplasmic vesicle
0.40	GO:0005794	Golgi apparatus
0.39	GO:0005923	bicellular tight junction
0.39	GO:0005829	cytosol
0.35	GO:0098588	bounding membrane of organelle

sp|P25095|AGTRA_RAT
Type-1A angiotensin II receptor
Search

AGTR1

0.97	Type-1 angiotensin II receptor

0.85	GO:0038166	angiotensin-activated signaling pathway
0.82	GO:0019229	regulation of vasoconstriction
0.42	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.42	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.41	GO:0042756	drinking behavior
0.41	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure
0.41	GO:0071549	cellular response to dexamethasone stimulus
0.41	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.40	GO:0045777	positive regulation of blood pressure

0.85	GO:0004945	angiotensin type II receptor activity
0.44	GO:0001596	angiotensin type I receptor activity
0.41	GO:0031711	bradykinin receptor binding
0.40	GO:0017046	peptide hormone binding
0.40	GO:0043621	protein self-association
0.38	GO:0031748	D1 dopamine receptor binding
0.37	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0019901	protein kinase binding

0.40	GO:0031983	vesicle lumen
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0012506	vesicle membrane
0.37	GO:0055037	recycling endosome
0.37	GO:0030425	dendrite
0.36	GO:0031968	organelle outer membrane
0.35	GO:0005794	Golgi apparatus
0.34	GO:0005887	integral component of plasma membrane

sp|P25099|AA1R_RAT
Adenosine receptor A1
Search

ADORA1

0.97	Adenosine receptor A1

0.85	GO:0001973	adenosine receptor signaling pathway
0.61	GO:0070256	negative regulation of mucus secretion
0.61	GO:1900453	negative regulation of long term synaptic depression
0.60	GO:0003093	regulation of glomerular filtration
0.59	GO:0051930	regulation of sensory perception of pain
0.58	GO:0002686	negative regulation of leukocyte migration
0.56	GO:0050728	negative regulation of inflammatory response
0.54	GO:0060079	excitatory postsynaptic potential
0.43	GO:0008285	negative regulation of cell proliferation
0.42	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.40	GO:0032795	heterotrimeric G-protein binding
0.38	GO:0031683	G-protein beta/gamma-subunit complex binding
0.38	GO:0001664	G-protein coupled receptor binding
0.38	GO:0004629	phospholipase C activity
0.37	GO:0031072	heat shock protein binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0001883	purine nucleoside binding

0.56	GO:0043197	dendritic spine
0.55	GO:0005886	plasma membrane
0.39	GO:0043195	terminal bouton
0.39	GO:0044304	main axon
0.38	GO:0014069	postsynaptic density
0.38	GO:0048786	presynaptic active zone
0.38	GO:0043025	neuronal cell body
0.38	GO:0031252	cell leading edge
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0042629	mast cell granule

sp|P25102|HRH2_RAT
Histamine H2 receptor
Search

HRH2

0.97	Histamine H2 receptor

0.83	GO:0001696	gastric acid secretion
0.81	GO:0045907	positive regulation of vasoconstriction
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0008542	visual learning
0.54	GO:0003382	epithelial cell morphogenesis
0.53	GO:0007613	memory
0.52	GO:0048167	regulation of synaptic plasticity
0.52	GO:0048565	digestive tract development
0.51	GO:0048732	gland development
0.51	GO:1901998	toxin transport

0.81	GO:0004969	histamine receptor activity
0.44	GO:0004952	dopamine neurotransmitter receptor activity
0.38	GO:0099589	serotonin receptor activity
0.35	GO:0051378	serotonin binding
0.35	GO:0004935	adrenergic receptor activity
0.34	GO:0001594	trace-amine receptor activity
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.33	GO:0009881	photoreceptor activity

0.41

GO:0005887

integral component of plasma membrane

0.34

GO:0004715

sp|P25108|ACHA_RAT
Acetylcholine receptor subunit alpha
Search

CHRNA1

0.94	Nicotinic acetylcholine recepter alpha-subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.47	GO:0007274	neuromuscular synaptic transmission
0.47	GO:0048630	skeletal muscle tissue growth
0.46	GO:0035094	response to nicotine
0.46	GO:0007271	synaptic transmission, cholinergic
0.46	GO:0070050	neuron cellular homeostasis
0.46	GO:0003009	skeletal muscle contraction
0.45	GO:0019228	neuronal action potential
0.45	GO:0046716	muscle cell cellular homeostasis

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.48	GO:0042166	acetylcholine binding
0.36	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.47	GO:0005892	acetylcholine-gated channel complex
0.45	GO:0031594	neuromuscular junction
0.42	GO:0009986	cell surface

sp|P25109|ACHB_RAT
Acetylcholine receptor subunit beta
Search

CHRNB1

0.97	Acetylcholine receptor subunit beta

0.79	GO:0060079	excitatory postsynaptic potential
0.64	GO:0007271	synaptic transmission, cholinergic
0.61	GO:0035094	response to nicotine
0.60	GO:0034220	ion transmembrane transport
0.60	GO:0007274	neuromuscular synaptic transmission
0.59	GO:0001941	postsynaptic membrane organization
0.57	GO:0048747	muscle fiber development
0.56	GO:0030534	adult behavior
0.56	GO:0006936	muscle contraction
0.51	GO:0050877	nervous system process

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.61	GO:0042166	acetylcholine binding
0.34	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.65	GO:0005892	acetylcholine-gated channel complex

sp|P25110|ACHD_RAT
Acetylcholine receptor subunit delta
Search

CHRND

0.90	Acetylcholine receptor subunit delta

0.78	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.50	GO:0048630	skeletal muscle tissue growth
0.49	GO:0035094	response to nicotine
0.49	GO:0007271	synaptic transmission, cholinergic
0.49	GO:0007274	neuromuscular synaptic transmission
0.48	GO:0050881	musculoskeletal movement
0.43	GO:0006941	striated muscle contraction
0.39	GO:0006812	cation transport
0.37	GO:0050905	neuromuscular process

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.53	GO:0042166	acetylcholine binding
0.37	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005515	protein binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.51	GO:0005892	acetylcholine-gated channel complex
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol

0.37

GO:0004252

sp|P25113|PGAM1_RAT
Phosphoglycerate mutase 1
Search

PGAM1

0.49	Phosphoglycerate mutase

0.68	GO:0006757	ATP generation from ADP
0.67	GO:0006090	pyruvate metabolic process
0.66	GO:0016052	carbohydrate catabolic process
0.65	GO:0019362	pyridine nucleotide metabolic process
0.53	GO:0043456	regulation of pentose-phosphate shunt
0.45	GO:0019319	hexose biosynthetic process
0.45	GO:0006006	glucose metabolic process
0.42	GO:0045730	respiratory burst
0.42	GO:0006110	regulation of glycolytic process
0.35	GO:1902093	positive regulation of flagellated sperm motility

0.79	GO:0004082	bisphosphoglycerate mutase activity
0.75	GO:0004619	phosphoglycerate mutase activity
0.40	GO:0019901	protein kinase binding
0.35	GO:0016787	hydrolase activity

0.47	GO:0043209	myelin sheath
0.45	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0097228	sperm principal piece
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.79

EC:5.4.2.4

GO:0004082

sp|P25114|F264_RAT
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
Search

PFKFB4

0.96	6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase-4 transcript variant 4

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.40	GO:0016311	dephosphorylation
0.35	GO:0045821	positive regulation of glycolytic process

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity

0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

sp|P25115|DRD5_RAT
D(1B) dopamine receptor
Search

DRD5

0.97	Dopamine receptor 5

0.85	GO:0007212	dopamine receptor signaling pathway
0.83	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.67	GO:0097746	regulation of blood vessel diameter
0.59	GO:0046960	sensitization
0.59	GO:0071870	cellular response to catecholamine stimulus
0.58	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.57	GO:0060292	long term synaptic depression
0.57	GO:0001975	response to amphetamine
0.56	GO:0042220	response to cocaine
0.56	GO:0001992	regulation of systemic arterial blood pressure by vasopressin

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.59	GO:0035240	dopamine binding
0.36	GO:0001965	G-protein alpha-subunit binding

0.67	GO:0005887	integral component of plasma membrane
0.57	GO:0060170	ciliary membrane
0.55	GO:0097730	non-motile cilium
0.54	GO:0031526	brush border membrane
0.45	GO:0005622	intracellular
0.37	GO:0012505	endomembrane system
0.35	GO:0043197	dendritic spine
0.35	GO:0043025	neuronal cell body
0.35	GO:0030424	axon

sp|P25122|KCNC1_RAT
Potassium voltage-gated channel subfamily C member 1
Search

KCNC1

0.96	Voltage-gated potassium channel type 3

0.74	GO:0051260	protein homooligomerization
0.74	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.54	GO:0051262	protein tetramerization
0.39	GO:0021759	globus pallidus development
0.39	GO:0035864	response to potassium ion
0.39	GO:1990089	response to nerve growth factor
0.39	GO:0014075	response to amine
0.39	GO:0010996	response to auditory stimulus
0.38	GO:0043268	positive regulation of potassium ion transport

0.78	GO:0005249	voltage-gated potassium channel activity
0.56	GO:0019894	kinesin binding
0.56	GO:0044325	ion channel binding
0.34	GO:0046983	protein dimerization activity
0.33	GO:0003676	nucleic acid binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.58	GO:0032809	neuronal cell body membrane
0.57	GO:0032590	dendrite membrane
0.57	GO:0030673	axolemma
0.37	GO:0009986	cell surface
0.34	GO:0043679	axon terminus
0.34	GO:0031594	neuromuscular junction
0.33	GO:0005634	nucleus
0.31	GO:0042734	presynaptic membrane
0.31	GO:0043204	perikaryon

sp|P25235|RPN2_RAT
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Search

RPN2

0.81	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

0.80	GO:0006487	protein N-linked glycosylation
0.40	GO:0007568	aging
0.38	GO:0042493	response to drug
0.36	GO:0018196	peptidyl-asparagine modification

0.49	GO:0016740	transferase activity
0.38	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding

0.82	GO:0008250	oligosaccharyltransferase complex
0.41	GO:0000421	autophagosome membrane
0.40	GO:0005791	rough endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0016740

sp|P25236|SEPP1_RAT
Selenoprotein P
Search

0.87	LOW QUALITY PROTEIN: selenoprotein P

0.49	GO:0001887	selenium compound metabolic process
0.49	GO:0007626	locomotory behavior
0.48	GO:0007420	brain development
0.47	GO:0009791	post-embryonic development
0.47	GO:0040007	growth
0.47	GO:0019953	sexual reproduction
0.44	GO:0010269	response to selenium ion
0.41	GO:0002576	platelet degranulation
0.37	GO:0006979	response to oxidative stress

0.85	GO:0008430	selenium binding
0.37	GO:0005515	protein binding

0.46	GO:0005576	extracellular region
0.42	GO:0031089	platelet dense granule lumen
0.30	GO:0016020	membrane

sp|P25286|VPP1_RAT
V-type proton ATPase 116 kDa subunit a isoform 1
Search

ATP6V0A1

0.58	V-type proton ATPase subunit a

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.53	GO:0016241	regulation of macroautophagy
0.51	GO:1901998	toxin transport
0.47	GO:0007035	vacuolar acidification
0.46	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.42	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.42	GO:0006754	ATP biosynthetic process
0.39	GO:0090382	phagosome maturation
0.38	GO:0097352	autophagosome maturation
0.37	GO:0001755	neural crest cell migration

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.56	GO:0051117	ATPase binding
0.45	GO:0036442	proton-exporting ATPase activity
0.43	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism

0.83	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain
0.51	GO:0016607	nuclear speck
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.46	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.42	GO:0042470	melanosome
0.42	GO:0005886	plasma membrane
0.40	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0099503	secretory vesicle

sp|P25304|AGRIN_RAT
Agrin
Search

AGRN

0.76	Agrin isoform C

0.75	GO:0043113	receptor clustering
0.74	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.45	GO:0007422	peripheral nervous system development
0.45	GO:0007417	central nervous system development
0.45	GO:0009952	anterior/posterior pattern specification
0.44	GO:0048699	generation of neurons
0.44	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.44	GO:0120036	plasma membrane bounded cell projection organization
0.44	GO:0000904	cell morphogenesis involved in differentiation
0.43	GO:0006898	receptor-mediated endocytosis

0.76	GO:0043236	laminin binding
0.70	GO:0005509	calcium ion binding
0.46	GO:0005044	scavenger receptor activity
0.38	GO:0099602	neurotransmitter receptor regulator activity
0.38	GO:0002162	dystroglycan binding
0.37	GO:0005539	glycosaminoglycan binding
0.36	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.36	GO:0033691	sialic acid binding
0.36	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.54	GO:0005605	basal lamina
0.51	GO:0005886	plasma membrane
0.45	GO:0005829	cytosol
0.38	GO:0045178	basal part of cell
0.38	GO:0031594	neuromuscular junction
0.37	GO:0030424	axon
0.36	GO:0005615	extracellular space
0.35	GO:0098857	membrane microdomain
0.35	GO:0030054	cell junction
0.30	GO:0031982	vesicle

0.34

GO:0004725

sp|P25305|CXB3_RAT
Gap junction beta-3 protein
Search

GJB3

0.64	Gap junction beta-3 protein (Fragment)

0.59	GO:0007154	cell communication
0.51	GO:0001890	placenta development
0.45	GO:0042048	olfactory behavior
0.42	GO:0007608	sensory perception of smell
0.39	GO:0001701	in utero embryonic development
0.39	GO:0071300	cellular response to retinoic acid
0.38	GO:0043588	skin development
0.38	GO:0007283	spermatogenesis
0.36	GO:1905867	epididymis development
0.35	GO:0048568	embryonic organ development

0.35	GO:0005243	gap junction channel activity
0.33	GO:0005515	protein binding

0.81	GO:0005922	connexin complex
0.42	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0005737	cytoplasm
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P25409|ALAT1_RAT
Alanine aminotransferase 1
Search

GPT

0.86	Mitochondrial alanine aminotransferase

0.49	GO:0009058	biosynthetic process
0.49	GO:0042851	L-alanine metabolic process
0.47	GO:0006103	2-oxoglutarate metabolic process
0.41	GO:0009080	pyruvate family amino acid catabolic process

0.67	GO:0030170	pyridoxal phosphate binding
0.61	GO:0008483	transaminase activity

0.46	GO:0005615	extracellular space
0.40	GO:0005739	mitochondrion
0.36	GO:1903561	extracellular vesicle
0.34	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

0.61

EC:2.6.1

GO:0008483

sp|P25427|NGF_RAT
Beta-nerve growth factor
Search

NGF

0.73	Beta-nerve growth factor

0.74	GO:0010469	regulation of receptor activity
0.54	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.52	GO:0048812	neuron projection morphogenesis
0.52	GO:0010951	negative regulation of endopeptidase activity
0.47	GO:0010628	positive regulation of gene expression
0.47	GO:0043524	negative regulation of neuron apoptotic process
0.45	GO:0045664	regulation of neuron differentiation
0.45	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.43	GO:0007267	cell-cell signaling
0.39	GO:0038179	neurotrophin signaling pathway

0.77	GO:0008083	growth factor activity
0.59	GO:0005163	nerve growth factor receptor binding
0.56	GO:0008191	metalloendopeptidase inhibitor activity
0.39	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0038177	death receptor agonist activity
0.36	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process

0.44	GO:0005576	extracellular region
0.43	GO:0031410	cytoplasmic vesicle
0.38	GO:0005796	Golgi lumen
0.37	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0044306	neuron projection terminus
0.30	GO:0016020	membrane

sp|P25809|KCRU_RAT
Creatine kinase U-type, mitochondrial
Search

0.87	Creatine kinase U-typeserine-threonine

0.57	GO:0016310	phosphorylation
0.46	GO:0032091	negative regulation of protein binding
0.44	GO:0043066	negative regulation of apoptotic process
0.36	GO:0006600	creatine metabolic process
0.36	GO:0021549	cerebellum development
0.36	GO:0007519	skeletal muscle tissue development
0.36	GO:0048565	digestive tract development
0.36	GO:0001822	kidney development

0.60	GO:0016301	kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.35	GO:0005515	protein binding

0.46	GO:0043209	myelin sheath
0.43	GO:0005739	mitochondrion
0.38	GO:0019866	organelle inner membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:0043204	perikaryon
0.30	GO:0044425	membrane part

0.40

EC:2.7.3

GO:0016775

sp|P25886|RL29_RAT
60S ribosomal protein L29
Search

RPL29

0.70	60S ribosomal protein L29

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0035264	multicellular organism growth
0.37	GO:0031589	cell-substrate adhesion
0.36	GO:0008283	cell proliferation
0.35	GO:0007566	embryo implantation
0.35	GO:0000188	inactivation of MAPK activity
0.35	GO:0007568	aging

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0045296	cadherin binding
0.38	GO:0008201	heparin binding
0.35	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.34	GO:0003723	RNA binding
0.32	GO:0016301	kinase activity

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.37	GO:0005844	polysome
0.36	GO:0019898	extrinsic component of membrane
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:1902493	acetyltransferase complex

0.35

EC:3.1.3

GO:0017017

sp|P25961|PTH1R_RAT
Parathyroid hormone/parathyroid hormone-related peptide receptor
Search

PTH1R

0.92	Parathyroid hormone 1 receptor a

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0002076	osteoblast development
0.59	GO:0045453	bone resorption
0.58	GO:0030282	bone mineralization
0.58	GO:0019933	cAMP-mediated signaling
0.57	GO:0002062	chondrocyte differentiation
0.55	GO:0048469	cell maturation
0.54	GO:0006874	cellular calcium ion homeostasis
0.54	GO:0008285	negative regulation of cell proliferation

0.86	GO:0004991	parathyroid hormone receptor activity
0.62	GO:0017046	peptide hormone binding
0.58	GO:0043621	protein self-association
0.53	GO:0042803	protein homodimerization activity
0.35	GO:0001653	peptide receptor activity

0.51	GO:0005886	plasma membrane
0.40	GO:0005903	brush border
0.40	GO:0045177	apical part of cell
0.39	GO:0043235	receptor complex
0.39	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P25977|UBF1_RAT
Nucleolar transcription factor 1
Search

UBTF

0.91	Nucleolar transcription factor 1

0.47	GO:0006360	transcription by RNA polymerase I
0.43	GO:0045943	positive regulation of transcription by RNA polymerase I
0.42	GO:1902659	regulation of glucose mediated signaling pathway
0.41	GO:0006354	DNA-templated transcription, elongation
0.41	GO:0000183	chromatin silencing at rDNA
0.41	GO:1990830	cellular response to leukemia inhibitory factor
0.36	GO:0006353	DNA-templated transcription, termination
0.36	GO:0006352	DNA-templated transcription, initiation

0.55	GO:0003677	DNA binding
0.48	GO:0097110	scaffold protein binding
0.45	GO:0003682	chromatin binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part

sp|P26051|CD44_RAT
CD44 antigen
Search

CD44

0.61	CD44 molecule (Indian blood group)

0.72	GO:0007155	cell adhesion
0.65	GO:1900623	regulation of monocyte aggregation
0.64	GO:2000392	regulation of lamellipodium morphogenesis
0.64	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.63	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.63	GO:0030214	hyaluronan catabolic process
0.63	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.62	GO:0044319	wound healing, spreading of cells
0.60	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.60	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.83	GO:0005540	hyaluronic acid binding
0.58	GO:0004896	cytokine receptor activity
0.45	GO:0005114	type II transforming growth factor beta receptor binding
0.43	GO:0019955	cytokine binding
0.42	GO:0005154	epidermal growth factor receptor binding
0.41	GO:0051219	phosphoprotein binding
0.40	GO:0019901	protein kinase binding
0.37	GO:0005518	collagen binding

0.65	GO:0035692	macrophage migration inhibitory factor receptor complex
0.63	GO:0031258	lamellipodium membrane
0.58	GO:0016324	apical plasma membrane
0.55	GO:0009986	cell surface
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005829	cytosol
0.47	GO:0016323	basolateral plasma membrane
0.45	GO:0005902	microvillus
0.42	GO:0005925	focal adhesion
0.42	GO:0070062	extracellular exosome

sp|P26255|ADRB3_RAT
Beta-3 adrenergic receptor
Search

ADRB3

0.96	Beta-3 adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.83	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.69	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.65	GO:0002024	diet induced thermogenesis
0.65	GO:0001659	temperature homeostasis
0.64	GO:0040015	negative regulation of multicellular organism growth
0.62	GO:0007190	activation of adenylate cyclase activity
0.62	GO:0050873	brown fat cell differentiation
0.61	GO:0044057	regulation of system process
0.60	GO:1902533	positive regulation of intracellular signal transduction

0.85	GO:0004939	beta-adrenergic receptor activity
0.67	GO:0051380	norepinephrine binding
0.63	GO:0031690	adrenergic receptor binding
0.57	GO:0051379	epinephrine binding
0.54	GO:0042803	protein homodimerization activity
0.48	GO:0005057	signal transducer activity, downstream of receptor
0.48	GO:0030165	PDZ domain binding
0.48	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.44	GO:0046982	protein heterodimerization activity
0.41	GO:0008179	adenylate cyclase binding

0.56	GO:0043235	receptor complex
0.55	GO:0005886	plasma membrane
0.49	GO:0005769	early endosome
0.39	GO:0045177	apical part of cell
0.39	GO:0005634	nucleus
0.34	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

0.35

EC:2.6.1

GO:0008483

sp|P26260|SDC1_RAT
Syndecan-1
Search

SDC1

0.79

Syndecan

0.72	GO:0042060	wound healing
0.63	GO:0048627	myoblast development
0.62	GO:1903553	positive regulation of extracellular exosome assembly
0.60	GO:1903543	positive regulation of exosomal secretion
0.57	GO:0060070	canonical Wnt signaling pathway
0.57	GO:0055002	striated muscle cell development
0.46	GO:0016477	cell migration
0.43	GO:0060009	Sertoli cell development
0.42	GO:0051591	response to cAMP
0.42	GO:0051384	response to glucocorticoid

0.57	GO:0008022	protein C-terminus binding
0.54	GO:0042802	identical protein binding
0.37	GO:0050840	extracellular matrix binding
0.33	GO:0003723	RNA binding
0.33	GO:0019838	growth factor binding
0.32	GO:0050694	galactose 3-O-sulfotransferase activity
0.32	GO:0005509	calcium ion binding

0.56	GO:0009897	external side of plasma membrane
0.45	GO:0044421	extracellular region part
0.41	GO:0031982	vesicle
0.40	GO:0005796	Golgi lumen
0.37	GO:0043202	lysosomal lumen
0.37	GO:0043234	protein complex
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0030424	axon

0.32

GO:0050694

sp|P26284|ODPA_RAT
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
Search

PDHA1

0.52	Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

0.79	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0006101	citrate metabolic process
0.42	GO:0019362	pyridine nucleotide metabolic process
0.41	GO:0006091	generation of precursor metabolites and energy
0.41	GO:0006006	glucose metabolic process
0.37	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate

0.78	GO:0004738	pyruvate dehydrogenase activity
0.76	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
0.45	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0005515	protein binding

0.55	GO:0043231	intracellular membrane-bounded organelle
0.49	GO:0045254	pyruvate dehydrogenase complex
0.47	GO:0043209	myelin sheath
0.47	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0043232	intracellular non-membrane-bounded organelle

0.76

EC:1.2.4

GO:0016624

sp|P26342|TGBR3_RAT
Transforming growth factor beta receptor type 3
Search

TGFBR3

0.96	Transforming growth factor beta receptor type 3

0.64	GO:0034699	response to luteinizing hormone
0.63	GO:0032354	response to follicle-stimulating hormone
0.62	GO:0060317	cardiac epithelial to mesenchymal transition
0.61	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.61	GO:0034695	response to prostaglandin E
0.59	GO:0030509	BMP signaling pathway
0.58	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0051271	negative regulation of cellular component movement
0.53	GO:0006955	immune response
0.47	GO:0035556	intracellular signal transduction

0.66	GO:0070123	transforming growth factor beta receptor activity, type III
0.63	GO:0050431	transforming growth factor beta binding
0.62	GO:0005114	type II transforming growth factor beta receptor binding
0.60	GO:0015026	coreceptor activity
0.59	GO:0046332	SMAD binding
0.45	GO:0005539	glycosaminoglycan binding
0.42	GO:0048185	activin binding
0.41	GO:0017134	fibroblast growth factor binding
0.40	GO:0030165	PDZ domain binding
0.39	GO:1901681	sulfur compound binding

0.63	GO:0034673	inhibin-betaglycan-ActRII complex
0.63	GO:0005576	extracellular region
0.57	GO:0009897	external side of plasma membrane
0.55	GO:0043235	receptor complex
0.41	GO:0005887	integral component of plasma membrane
0.38	GO:0005622	intracellular
0.36	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system

sp|P26376|IFM3_RAT
Interferon-induced transmembrane protein 3
Search

IFITM3

0.95	Interferon-induced transmembrane protein 3

0.70	GO:0009607	response to biotic stimulus
0.47	GO:0046597	negative regulation of viral entry into host cell
0.45	GO:0035455	response to interferon-alpha
0.45	GO:0035456	response to interferon-beta
0.45	GO:0045071	negative regulation of viral genome replication
0.44	GO:0034341	response to interferon-gamma
0.43	GO:0002252	immune effector process
0.42	GO:0060337	type I interferon signaling pathway
0.41	GO:0009605	response to external stimulus
0.40	GO:0032897	negative regulation of viral transcription

0.34	GO:0005515	protein binding
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0005765	lysosomal membrane
0.38	GO:0012505	endomembrane system
0.38	GO:0045177	apical part of cell
0.37	GO:0009986	cell surface
0.37	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P26431|SL9A1_RAT
Sodium/hydrogen exchanger 1
Search

SLC9A1

0.59	Sodium/hydrogen exchanger

0.79	GO:0006885	regulation of pH
0.77	GO:0035725	sodium ion transmembrane transport
0.63	GO:0086092	regulation of the force of heart contraction by cardiac conduction
0.63	GO:1903281	positive regulation of calcium:sodium antiporter activity
0.63	GO:1902600	hydrogen ion transmembrane transport
0.62	GO:0098735	positive regulation of the force of heart contraction
0.62	GO:0071872	cellular response to epinephrine stimulus
0.61	GO:0071468	cellular response to acidic pH
0.61	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade
0.61	GO:0006883	cellular sodium ion homeostasis

0.82	GO:0015385	sodium:proton antiporter activity
0.61	GO:0030346	protein phosphatase 2B binding
0.60	GO:0048306	calcium-dependent protein binding
0.47	GO:0015386	potassium:proton antiporter activity
0.42	GO:0005516	calmodulin binding
0.35	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0032947	protein complex scaffold activity
0.35	GO:0030674	protein binding, bridging

0.58	GO:0090533	cation-transporting ATPase complex
0.56	GO:0016324	apical plasma membrane
0.56	GO:0098857	membrane microdomain
0.50	GO:0005654	nucleoplasm
0.49	GO:0005887	integral component of plasma membrane
0.41	GO:0030315	T-tubule
0.41	GO:0014704	intercalated disc
0.40	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0016323	basolateral plasma membrane

sp|P26433|SL9A3_RAT
Sodium/hydrogen exchanger 3
Search

SLC9A3

0.58	Sodium/hydrogen exchanger

0.79	GO:0006885	regulation of pH
0.77	GO:0035725	sodium ion transmembrane transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0099587	inorganic ion import across plasma membrane
0.50	GO:0030004	cellular monovalent inorganic cation homeostasis
0.46	GO:0071805	potassium ion transmembrane transport
0.38	GO:0051384	response to glucocorticoid
0.36	GO:0010037	response to carbon dioxide
0.36	GO:0002028	regulation of sodium ion transport
0.36	GO:1901654	response to ketone

0.82	GO:0015385	sodium:proton antiporter activity
0.57	GO:0030165	PDZ domain binding
0.51	GO:0015386	potassium:proton antiporter activity

0.59	GO:0031526	brush border membrane
0.57	GO:0016324	apical plasma membrane
0.54	GO:0070062	extracellular exosome
0.36	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P26434|SL9A4_RAT
Sodium/hydrogen exchanger 4
Search

SLC9A4

0.59	Sodium/hydrogen exchanger

0.79	GO:0006885	regulation of pH
0.77	GO:0035725	sodium ion transmembrane transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.56	GO:0001696	gastric acid secretion
0.52	GO:0002064	epithelial cell development
0.51	GO:0099587	inorganic ion import across plasma membrane
0.50	GO:0030004	cellular monovalent inorganic cation homeostasis
0.47	GO:0071805	potassium ion transmembrane transport
0.44	GO:0008104	protein localization
0.35	GO:0007165	signal transduction

0.82	GO:0015385	sodium:proton antiporter activity
0.51	GO:0015386	potassium:proton antiporter activity

0.40	GO:0005886	plasma membrane
0.39	GO:0045177	apical part of cell
0.34	GO:0005903	brush border
0.30	GO:0016021	integral component of membrane

sp|P26435|NTCP_RAT
Sodium/bile acid cotransporter
Search

SLC10A1

0.96	Hepatic sodium-dependent bile acid transporter

0.82	GO:0015721	bile acid and bile salt transport
0.38	GO:0006814	sodium ion transport
0.38	GO:0030534	adult behavior
0.36	GO:0042493	response to drug
0.35	GO:0043251	sodium-dependent organic anion transport
0.35	GO:0055085	transmembrane transport
0.34	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.34	GO:0044409	entry into host
0.33	GO:0019058	viral life cycle

0.84	GO:0008508	bile acid:sodium symporter activity
0.35	GO:0104005	hijacked molecular function
0.35	GO:0043250	sodium-dependent organic anion transmembrane transporter activity

0.45	GO:0098590	plasma membrane region
0.44	GO:0045177	apical part of cell
0.34	GO:0005887	integral component of plasma membrane

sp|P26453|BASI_RAT
Basigin
Search

BSG

0.95	Leukocyte activation antigen M6

0.42	GO:0072659	protein localization to plasma membrane
0.41	GO:0046697	decidualization
0.41	GO:0007566	embryo implantation
0.41	GO:0051591	response to cAMP
0.41	GO:0042475	odontogenesis of dentin-containing tooth
0.40	GO:0043434	response to peptide hormone
0.40	GO:0046689	response to mercury ion
0.39	GO:0002027	regulation of heart rate
0.37	GO:0071805	potassium ion transmembrane transport
0.37	GO:0006814	sodium ion transport

0.50	GO:0045296	cadherin binding
0.42	GO:0005537	mannose binding
0.39	GO:0030552	cAMP binding
0.38	GO:0005249	voltage-gated potassium channel activity
0.36	GO:0004252	serine-type endopeptidase activity
0.35	GO:0008028	monocarboxylic acid transmembrane transporter activity

0.53	GO:0002080	acrosomal membrane
0.43	GO:0042470	melanosome
0.40	GO:0005886	plasma membrane
0.40	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0045121	membrane raft
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.36

GO:0004252

sp|P26644|APOH_RAT
Beta-2-glycoprotein 1
Search

APOH

0.88	Apolipoprotein H

0.86	GO:0007597	blood coagulation, intrinsic pathway
0.86	GO:0034392	negative regulation of smooth muscle cell apoptotic process
0.86	GO:0051918	negative regulation of fibrinolysis
0.85	GO:0051006	positive regulation of lipoprotein lipase activity
0.85	GO:0033033	negative regulation of myeloid cell apoptotic process
0.84	GO:0031639	plasminogen activation
0.84	GO:0001937	negative regulation of endothelial cell proliferation
0.84	GO:0010596	negative regulation of endothelial cell migration
0.84	GO:0030195	negative regulation of blood coagulation
0.81	GO:0016525	negative regulation of angiogenesis

0.86	GO:0060230	lipoprotein lipase activator activity
0.73	GO:0005543	phospholipid binding
0.72	GO:0042802	identical protein binding
0.50	GO:0008201	heparin binding
0.38	GO:0004875	complement receptor activity
0.38	GO:0001848	complement binding
0.35	GO:0046983	protein dimerization activity
0.33	GO:0003677	DNA binding

0.84	GO:0042627	chylomicron
0.84	GO:0034361	very-low-density lipoprotein particle
0.84	GO:0034364	high-density lipoprotein particle
0.73	GO:0009986	cell surface
0.72	GO:0031012	extracellular matrix
0.46	GO:0070062	extracellular exosome
0.38	GO:0005886	plasma membrane
0.36	GO:0043235	receptor complex
0.36	GO:0098552	side of membrane
0.36	GO:0005737	cytoplasm

sp|P26684|EDNRA_RAT
Endothelin-1 receptor
Search

EDNRA

0.97	Endothelin receptor type A

0.86	GO:0086100	endothelin receptor signaling pathway
0.85	GO:0048484	enteric nervous system development
0.85	GO:0042310	vasoconstriction
0.83	GO:0008217	regulation of blood pressure
0.61	GO:0014820	tonic smooth muscle contraction
0.59	GO:0001569	branching involved in blood vessel morphogenesis
0.58	GO:0007585	respiratory gaseous exchange
0.57	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.57	GO:0014032	neural crest cell development
0.56	GO:0015758	glucose transport

0.86	GO:0004962	endothelin receptor activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding
0.32	GO:0003735	structural constituent of ribosome

0.36	GO:0005886	plasma membrane
0.35	GO:0098857	membrane microdomain
0.35	GO:0031965	nuclear membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P26769|ADCY2_RAT
Adenylate cyclase type 2
Search

ADCY2

0.83	Adenylate cyclase type 2

0.79	GO:0006171	cAMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.47	GO:0006182	cGMP biosynthetic process
0.40	GO:1904321	response to forskolin
0.39	GO:1901655	cellular response to ketone
0.38	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.38	GO:0035690	cellular response to drug
0.38	GO:0007190	activation of adenylate cyclase activity
0.38	GO:0071396	cellular response to lipid
0.38	GO:0071407	cellular response to organic cyclic compound

0.79	GO:0004016	adenylate cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.48	GO:0043168	anion binding
0.47	GO:0004383	guanylate cyclase activity
0.40	GO:0008179	adenylate cyclase binding
0.37	GO:0046982	protein heterodimerization activity
0.37	GO:0030145	manganese ion binding

0.55	GO:0005886	plasma membrane
0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0030425	dendrite
0.37	GO:0045121	membrane raft
0.30	GO:0016021	integral component of membrane

0.79

GO:0004016

sp|P26770|ADCY4_RAT
Adenylate cyclase type 4
Search

ADCY4

0.79	Adenylate cyclase type 4

0.79	GO:0006171	cAMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.54	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.51	GO:0006182	cGMP biosynthetic process
0.39	GO:0007190	activation of adenylate cyclase activity
0.37	GO:1904321	response to forskolin
0.36	GO:1901701	cellular response to oxygen-containing compound
0.36	GO:0071310	cellular response to organic substance
0.36	GO:0034199	activation of protein kinase A activity
0.36	GO:0035690	cellular response to drug

0.80	GO:0004016	adenylate cyclase activity
0.56	GO:0005080	protein kinase C binding
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0008144	drug binding
0.51	GO:0036094	small molecule binding
0.51	GO:0004383	guanylate cyclase activity
0.50	GO:0043168	anion binding
0.37	GO:0031683	G-protein beta/gamma-subunit complex binding
0.37	GO:0008179	adenylate cyclase binding

0.55	GO:0005886	plasma membrane
0.53	GO:0030425	dendrite
0.52	GO:0008074	guanylate cyclase complex, soluble
0.34	GO:0045121	membrane raft
0.30	GO:0016021	integral component of membrane

0.80

GO:0004016

sp|P26772|CH10_RAT
10 kDa heat shock protein, mitochondrial
Search

HSPE1

0.83	Heat shock protein, mitochondrial

0.68	GO:0006457	protein folding
0.50	GO:0006986	response to unfolded protein
0.38	GO:0001649	osteoblast differentiation
0.36	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process

0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0051087	chaperone binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0051082	unfolded protein binding
0.39	GO:0046872	metal ion binding
0.35	GO:0003723	RNA binding

0.48	GO:0005737	cytoplasm
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P26794|PIM1_RAT
Serine/threonine-protein kinase pim-1
Search

PIM1

0.93	Proto-oncogene serine/threonine-protein kinase pim-1

0.76	GO:0043066	negative regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.56	GO:1905062	positive regulation of cardioblast proliferation
0.54	GO:0070561	vitamin D receptor signaling pathway
0.53	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.51	GO:0043433	negative regulation of DNA binding transcription factor activity
0.50	GO:0007346	regulation of mitotic cell cycle
0.49	GO:0008283	cell proliferation
0.46	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.44	GO:0007634	optokinetic behavior

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0043024	ribosomal small subunit binding
0.47	GO:0008134	transcription factor binding
0.47	GO:0030145	manganese ion binding
0.33	GO:0005509	calcium ion binding

0.49	GO:0005829	cytosol
0.47	GO:0005730	nucleolus
0.34	GO:0005886	plasma membrane
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

sp|P26801|CEBPG_RAT
CCAAT/enhancer-binding protein gamma
Search

CEBPG

0.97	CCAAT/enhancer-binding protein gamma

0.60	GO:0043353	enucleate erythrocyte differentiation
0.60	GO:0045078	positive regulation of interferon-gamma biosynthetic process
0.59	GO:0042267	natural killer cell mediated cytotoxicity
0.57	GO:0045739	positive regulation of DNA repair
0.57	GO:0030183	B cell differentiation
0.56	GO:0043433	negative regulation of DNA binding transcription factor activity
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0016071	mRNA metabolic process
0.41	GO:0001889	liver development

0.57	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.51	GO:0008134	transcription factor binding
0.40	GO:0044374	sequence-specific DNA binding, bending

0.49	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P26817|ARBK1_RAT
Beta-adrenergic receptor kinase 1
Search

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0007165	signal transduction
0.60	GO:0031623	receptor internalization
0.57	GO:0003108	negative regulation of the force of heart contraction by chemical signal
0.55	GO:0045988	negative regulation of striated muscle contraction
0.55	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway
0.53	GO:0060048	cardiac muscle contraction
0.52	GO:0007507	heart development
0.52	GO:0018210	peptidyl-threonine modification
0.51	GO:0018209	peptidyl-serine modification

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.57	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0047696	beta-adrenergic receptor kinase activity
0.37	GO:0031694	alpha-2A adrenergic receptor binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004725	protein tyrosine phosphatase activity

0.38	GO:0005737	cytoplasm
0.36	GO:0120025	plasma membrane bounded cell projection
0.36	GO:0005886	plasma membrane
0.34	GO:0045121	membrane raft
0.34	GO:0045177	apical part of cell
0.34	GO:0036477	somatodendritic compartment
0.34	GO:0098794	postsynapse
0.34	GO:0044463	cell projection part
0.33	GO:0043226	organelle

0.85

EC:2.7.11.16

GO:0004703

sp|P26819|ARBK2_RAT
Beta-adrenergic receptor kinase 2
Search

GRK3

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0031623	receptor internalization
0.61	GO:0007165	signal transduction
0.52	GO:0003108	negative regulation of the force of heart contraction by chemical signal
0.51	GO:0045988	negative regulation of striated muscle contraction
0.50	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway
0.49	GO:0007507	heart development
0.49	GO:0060048	cardiac muscle contraction
0.47	GO:0018210	peptidyl-threonine modification
0.47	GO:0018209	peptidyl-serine modification

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.46	GO:0047696	beta-adrenergic receptor kinase activity
0.37	GO:0031694	alpha-2A adrenergic receptor binding
0.35	GO:0031748	D1 dopamine receptor binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding

0.37	GO:0005737	cytoplasm
0.36	GO:0005929	cilium
0.35	GO:0044292	dendrite terminus
0.35	GO:0043198	dendritic shaft
0.35	GO:0005886	plasma membrane
0.35	GO:0043197	dendritic spine
0.35	GO:0097223	sperm part
0.34	GO:0030424	axon
0.34	GO:0099512	supramolecular fiber
0.33	GO:0043232	intracellular non-membrane-bounded organelle

0.85

EC:2.7.11.16

GO:0004703

sp|P26824|PAR1_RAT
Proteinase-activated receptor 1
Search

F2R

0.97	Coagulation factor II thrombin receptor

0.85	GO:0070493	thrombin-activated receptor signaling pathway
0.81	GO:0007596	blood coagulation
0.69	GO:1900133	regulation of renin secretion into blood stream
0.68	GO:0035025	positive regulation of Rho protein signal transduction
0.66	GO:2000484	positive regulation of interleukin-8 secretion
0.65	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.65	GO:1903524	positive regulation of blood circulation
0.65	GO:2000778	positive regulation of interleukin-6 secretion
0.65	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.64	GO:0030193	regulation of blood coagulation

0.85	GO:0015057	thrombin-activated receptor activity
0.68	GO:0031681	G-protein beta-subunit binding
0.66	GO:0001965	G-protein alpha-subunit binding
0.51	GO:0005102	receptor binding
0.38	GO:0032795	heterotrimeric G-protein binding
0.37	GO:0004994	somatostatin receptor activity
0.33	GO:0008233	peptidase activity

0.62	GO:0031094	platelet dense tubular network
0.58	GO:0005901	caveola
0.58	GO:0005769	early endosome
0.55	GO:0005770	late endosome
0.52	GO:0009986	cell surface
0.50	GO:0031594	neuromuscular junction
0.48	GO:0045211	postsynaptic membrane
0.48	GO:0031143	pseudopodium
0.46	GO:0005887	integral component of plasma membrane
0.35	GO:0005794	Golgi apparatus

0.33

GO:0008233

sp|P26896|IL2RB_RAT
Interleukin-2 receptor subunit beta
Search

IL2RB

0.97	Interleukin-2 receptor subunit beta

0.78	GO:0019221	cytokine-mediated signaling pathway
0.68	GO:0071352	cellular response to interleukin-2
0.60	GO:0043066	negative regulation of apoptotic process
0.42	GO:0030101	natural killer cell activation
0.39	GO:0071350	cellular response to interleukin-15
0.37	GO:0000165	MAPK cascade
0.36	GO:0006461	protein complex assembly
0.35	GO:0065009	regulation of molecular function
0.35	GO:0016032	viral process

0.80	GO:0004896	cytokine receptor activity
0.68	GO:0019976	interleukin-2 binding
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.61	GO:0009897	external side of plasma membrane
0.37	GO:0005768	endosome
0.36	GO:0005829	cytosol
0.36	GO:0005887	integral component of plasma membrane

sp|P26897|IL2RA_RAT
Interleukin-2 receptor subunit alpha
Search

IL2RA

0.97	Interleukin-2 receptor subunit alpha

0.87	GO:0038110	interleukin-2-mediated signaling pathway
0.71	GO:0002664	regulation of T cell tolerance induction
0.69	GO:0046013	regulation of T cell homeostatic proliferation
0.69	GO:0006924	activation-induced cell death of T cells
0.66	GO:0042104	positive regulation of activated T cell proliferation
0.65	GO:0042130	negative regulation of T cell proliferation
0.64	GO:0050728	negative regulation of inflammatory response
0.62	GO:0007219	Notch signaling pathway
0.53	GO:0006954	inflammatory response
0.50	GO:0006955	immune response

0.87	GO:0004911	interleukin-2 receptor activity
0.87	GO:0019976	interleukin-2 binding
0.38	GO:0008144	drug binding
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.62	GO:0009897	external side of plasma membrane
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P27008|PARP1_RAT
Poly [ADP-ribose] polymerase 1
Search

PARP1

0.57	Poly [ADP-ribose] polymerase

0.83	GO:0006471	protein ADP-ribosylation
0.63	GO:1990966	ATP generation from poly-ADP-D-ribose
0.62	GO:1903518	positive regulation of single strand break repair
0.61	GO:2001170	negative regulation of ATP biosynthetic process
0.59	GO:0043504	mitochondrial DNA repair
0.57	GO:0032869	cellular response to insulin stimulus
0.57	GO:0018209	peptidyl-serine modification
0.56	GO:0034644	cellular response to UV
0.53	GO:0006915	apoptotic process
0.53	GO:0006302	double-strand break repair

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.65	GO:0051287	NAD binding
0.63	GO:1990404	protein ADP-ribosylase activity
0.62	GO:0008270	zinc ion binding
0.57	GO:0047485	protein N-terminus binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.54	GO:0019901	protein kinase binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0042802	identical protein binding

0.59	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.50	GO:0032993	protein-DNA complex
0.49	GO:0070013	intracellular organelle lumen
0.49	GO:0012505	endomembrane system
0.46	GO:0031967	organelle envelope
0.45	GO:0005739	mitochondrion
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.81

EC:2.4.2.30

GO:0003950

sp|P27049|BTG2_RAT
Protein BTG2
Search

BTG2

0.96	B-cell translocation gene 2, anti-proliferative

0.79	GO:0008285	negative regulation of cell proliferation
0.57	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.56	GO:0021542	dentate gyrus development
0.55	GO:0035914	skeletal muscle cell differentiation
0.54	GO:0008306	associative learning
0.54	GO:0021954	central nervous system neuron development
0.54	GO:2000177	regulation of neural precursor cell proliferation
0.53	GO:0009952	anterior/posterior pattern specification
0.52	GO:0031175	neuron projection development
0.51	GO:0017148	negative regulation of translation

0.44	GO:0019899	enzyme binding
0.39	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003712	transcription cofactor activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome

sp|P27139|CAH2_RAT
Carbonic anhydrase 2
Search

CA2

0.44	Erythrocyte carbonic anhydrase

0.70	GO:0006730	one-carbon metabolic process
0.56	GO:0038166	angiotensin-activated signaling pathway
0.55	GO:0015670	carbon dioxide transport
0.55	GO:0044070	regulation of anion transport
0.55	GO:2000878	positive regulation of oligopeptide transport
0.55	GO:2001148	regulation of dipeptide transmembrane transport
0.53	GO:0032849	positive regulation of cellular pH reduction
0.52	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.50	GO:0034764	positive regulation of transmembrane transport
0.47	GO:0002009	morphogenesis of an epithelium

0.75	GO:0004089	carbonate dehydratase activity
0.61	GO:0008270	zinc ion binding
0.55	GO:0004064	arylesterase activity
0.34	GO:0005515	protein binding
0.33	GO:0016151	nickel cation binding

0.52	GO:0045177	apical part of cell
0.49	GO:0043209	myelin sheath
0.44	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.39	GO:0005902	microvillus
0.38	GO:0030424	axon
0.37	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.75

EC:4.2.1.1

GO:0004089

sp|P27158|KITH_RAT
Thymidine kinase, cytosolic (Fragment)
Search

0.38	Thymidine kinase

0.76	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
0.67	GO:0071897	DNA biosynthetic process
0.57	GO:0016310	phosphorylation
0.55	GO:0051289	protein homotetramerization
0.47	GO:0046104	thymidine metabolic process
0.36	GO:0060138	fetal process involved in parturition
0.36	GO:0014856	skeletal muscle cell proliferation
0.36	GO:0051414	response to cortisol
0.35	GO:0009165	nucleotide biosynthetic process
0.35	GO:0001889	liver development

0.81	GO:0004797	thymidine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042802	identical protein binding
0.45	GO:0008270	zinc ion binding

0.35

GO:0005829

cytosol

0.81

EC:2.7.1.21

GO:0004797

sp|P27213|PTPS_RAT
6-pyruvoyl tetrahydrobiopterin synthase
Search

PTS

0.71	6-pyruvoyl tetrahydrobiopterin synthase

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.65	GO:0009108	coenzyme biosynthetic process
0.34	GO:0007417	central nervous system development
0.34	GO:0046655	folic acid metabolic process
0.33	GO:0007018	microtubule-based movement
0.33	GO:0006979	response to oxidative stress
0.33	GO:0042398	cellular modified amino acid biosynthetic process
0.33	GO:0043650	dicarboxylic acid biosynthetic process

0.86	GO:0003874	6-pyruvoyltetrahydropterin synthase activity
0.48	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.45	GO:0046872	metal ion binding
0.34	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol

0.86	EC:4.2.3.12	GO:0003874
0.86	KEGG:R04286	GO:0003874

sp|P27274|CD59_RAT
CD59 glycoprotein
Search

CD59

0.79	CD59 molecule (CD59 blood group)

0.87	GO:0001971	negative regulation of activation of membrane attack complex
0.47	GO:0045918	negative regulation of cytolysis
0.45	GO:0042102	positive regulation of T cell proliferation
0.43	GO:0043066	negative regulation of apoptotic process
0.41	GO:0007166	cell surface receptor signaling pathway

0.46

GO:0001848

complement binding

0.48	GO:0031362	anchored component of external side of plasma membrane
0.46	GO:0043218	compact myelin
0.45	GO:0042383	sarcolemma
0.44	GO:0005925	focal adhesion
0.44	GO:0070062	extracellular exosome

sp|P27321|ICAL_RAT
Calpastatin
Search

CAST

0.44	Calpastatin

0.65	GO:0010951	negative regulation of endopeptidase activity
0.61	GO:2000675	negative regulation of type B pancreatic cell apoptotic process
0.60	GO:0097341	zymogen inhibition
0.56	GO:2000116	regulation of cysteine-type endopeptidase activity
0.37	GO:0030163	protein catabolic process
0.30	GO:0031100	animal organ regeneration
0.30	GO:0010948	negative regulation of cell cycle process
0.30	GO:0060322	head development
0.30	GO:0001889	liver development
0.30	GO:0009987	cellular process

0.73	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity
0.55	GO:0045296	cadherin binding
0.30	GO:0003723	RNA binding
0.30	GO:0002020	protease binding

0.63	GO:0005783	endoplasmic reticulum
0.61	GO:0005829	cytosol
0.30	GO:0016020	membrane
0.30	GO:0005634	nucleus

sp|P27364|3BHS5_RAT
3 beta-hydroxysteroid dehydrogenase type 5
Search

0.50	3 beta-hydroxysteroid dehydrogenase isomerase VI

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0034754	cellular hormone metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.39	GO:0014070	response to organic cyclic compound
0.38	GO:0010288	response to lead ion
0.38	GO:0033327	Leydig cell differentiation
0.38	GO:0034698	response to gonadotropin
0.37	GO:0008211	glucocorticoid metabolic process
0.37	GO:0021766	hippocampus development

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.54	GO:0102294	cholesterol dehydrogenase activity
0.54	GO:0004769	steroid delta-isomerase activity
0.38	GO:0010181	FMN binding
0.37	GO:0005496	steroid binding
0.36	GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity
0.36	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.35	GO:0051287	NAD binding
0.35	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.33	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.46	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0031966	mitochondrial membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.41	GO:0019866	organelle inner membrane
0.39	GO:0097425	smooth endoplasmic reticulum part
0.36	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.83

EC:1.1.1.145

GO:0003854

sp|P27435|TRYB1_RAT
Tryptase
Search

0.80	Mast cell tryptase beta III

0.61	GO:0006508	proteolysis
0.39	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.38	GO:0022617	extracellular matrix disassembly
0.37	GO:0050878	regulation of body fluid levels
0.37	GO:0050819	negative regulation of coagulation
0.37	GO:0061045	negative regulation of wound healing
0.36	GO:0050817	coagulation
0.36	GO:0042060	wound healing
0.35	GO:0006952	defense response
0.34	GO:0048771	tissue remodeling

0.69	GO:0004252	serine-type endopeptidase activity
0.40	GO:0008201	heparin binding
0.35	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0005044	scavenger receptor activity

0.43	GO:0005576	extracellular region
0.38	GO:0042629	mast cell granule
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P27590|UROM_RAT
Uromodulin
Search

UMOD

0.93	Pancreatic zymogen granule membrane protein GP-2

0.62	GO:0072233	metanephric thick ascending limb development
0.61	GO:0072221	metanephric distal convoluted tubule development
0.61	GO:0072021	ascending thin limb development
0.61	GO:0072236	metanephric loop of Henle development
0.58	GO:0007588	excretion
0.58	GO:0007159	leukocyte cell-cell adhesion
0.57	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.57	GO:1990266	neutrophil migration
0.55	GO:2000021	regulation of ion homeostasis
0.51	GO:0048878	chemical homeostasis

0.62	GO:0005509	calcium ion binding
0.60	GO:0019864	IgG binding
0.36	GO:0003823	antigen binding
0.35	GO:0005201	extracellular matrix structural constituent
0.35	GO:0051537	2 iron, 2 sulfur cluster binding
0.32	GO:0016301	kinase activity
0.32	GO:0004930	G-protein coupled receptor activity

0.64	GO:0005576	extracellular region
0.57	GO:0016324	apical plasma membrane
0.56	GO:0016323	basolateral plasma membrane
0.56	GO:0031225	anchored component of membrane
0.55	GO:0000922	spindle pole
0.53	GO:0005929	cilium
0.44	GO:0031253	cell projection membrane
0.41	GO:0098588	bounding membrane of organelle
0.38	GO:0031982	vesicle
0.37	GO:0005794	Golgi apparatus

sp|P27605|HPRT_RAT
Hypoxanthine-guanine phosphoribosyltransferase
Search

HPRT1

0.50	Hypoxanthine-guanine phosphoribosyltransferase

0.78	GO:0032264	IMP salvage
0.75	GO:0006166	purine ribonucleoside salvage
0.59	GO:0046038	GMP catabolic process
0.58	GO:0006178	guanine salvage
0.58	GO:0045915	positive regulation of catecholamine metabolic process
0.57	GO:0042053	regulation of dopamine metabolic process
0.54	GO:0051289	protein homotetramerization
0.54	GO:0046100	hypoxanthine metabolic process
0.54	GO:0007625	grooming behavior
0.54	GO:0021756	striatum development

0.79	GO:0004422	hypoxanthine phosphoribosyltransferase activity
0.79	GO:0052657	guanine phosphoribosyltransferase activity
0.53	GO:0046872	metal ion binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0036094	small molecule binding

0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome

0.79	EC:2.4.2.8	GO:0004422
0.79	KEGG:R01132	GO:0004422

sp|P27615|SCRB2_RAT
Lysosome membrane protein 2
Search

SCARB2

0.87	Scavenger receptor class B member 2

0.72	GO:1905123	regulation of glucosylceramidase activity
0.70	GO:0006622	protein targeting to lysosome
0.66	GO:0001508	action potential
0.44	GO:0030903	notochord development
0.38	GO:0010976	positive regulation of neuron projection development

0.65	GO:0004872	receptor activity
0.58	GO:0019899	enzyme binding

0.79	GO:0005764	lysosome
0.67	GO:0005775	vacuolar lumen
0.62	GO:0098852	lytic vacuole membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P27645|FCGR3_RAT
Low affinity immunoglobulin gamma Fc region receptor III
Search

FCGR2A

0.95	Low affinity immunoglobulin gamma Fc region receptor III-A

0.46	GO:0038094	Fc-gamma receptor signaling pathway
0.44	GO:0002274	myeloid leukocyte activation
0.43	GO:0001810	regulation of type I hypersensitivity
0.42	GO:0006909	phagocytosis
0.42	GO:0002443	leukocyte mediated immunity
0.41	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.41	GO:0050766	positive regulation of phagocytosis
0.41	GO:0099024	plasma membrane invagination
0.41	GO:0051239	regulation of multicellular organismal process
0.41	GO:0050778	positive regulation of immune response

0.49	GO:0019864	IgG binding
0.46	GO:0019770	IgG receptor activity
0.40	GO:0019767	IgE receptor activity
0.38	GO:0001540	amyloid-beta binding
0.36	GO:0034987	immunoglobulin receptor binding
0.34	GO:0019863	IgE binding
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.42	GO:0009986	cell surface
0.39	GO:0098552	side of membrane
0.38	GO:0070062	extracellular exosome
0.38	GO:0005886	plasma membrane
0.37	GO:0043197	dendritic spine
0.37	GO:0044297	cell body
0.36	GO:0030667	secretory granule membrane
0.35	GO:0055037	recycling endosome
0.34	GO:0098857	membrane microdomain
0.34	GO:0031225	anchored component of membrane

sp|P27653|C1TC_RAT
C-1-tetrahydrofolate synthase, cytoplasmic
Search

MTHFD1

0.90	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

0.60	GO:0009257	10-formyltetrahydrofolate biosynthetic process
0.56	GO:0001780	neutrophil homeostasis
0.56	GO:0019346	transsulfuration
0.54	GO:0001843	neural tube closure
0.54	GO:0061053	somite development
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0007507	heart development
0.50	GO:0035999	tetrahydrofolate interconversion
0.49	GO:0009086	methionine biosynthetic process
0.48	GO:0009070	serine family amino acid biosynthetic process

0.81	GO:0004329	formate-tetrahydrofolate ligase activity
0.78	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.56	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity
0.38	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
0.33	GO:0005515	protein binding

0.47	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81	EC:6.3.4.3	GO:0004329
0.78	KEGG:R01220	GO:0004488

sp|P27657|LIPP_RAT
Pancreatic triacylglycerol lipase
Search

0.59	Pancreatic triacylglycerol lipase

0.69	GO:0016042	lipid catabolic process
0.59	GO:0007586	digestion
0.55	GO:0061365	positive regulation of triglyceride lipase activity
0.53	GO:0030301	cholesterol transport
0.50	GO:0006968	cellular defense response
0.48	GO:0003008	system process
0.36	GO:0042750	hibernation
0.35	GO:0043434	response to peptide hormone
0.35	GO:0001523	retinoid metabolic process
0.35	GO:0009791	post-embryonic development

0.78	GO:0004806	triglyceride lipase activity
0.36	GO:0046872	metal ion binding

0.65

GO:0005576

extracellular region

0.78

EC:3.1.1.3

GO:0004806

sp|P27682|7B2_RAT
Neuroendocrine protein 7B2
Search

SCG5

0.90	Secretogranin V

0.80	GO:0007218	neuropeptide signaling pathway
0.58	GO:0016486	peptide hormone processing
0.56	GO:0046883	regulation of hormone secretion
0.51	GO:0043086	negative regulation of catalytic activity
0.50	GO:0006886	intracellular protein transport

0.52	GO:0004857	enzyme inhibitor activity
0.51	GO:0051082	unfolded protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0030141	secretory granule
0.38	GO:0005576	extracellular region
0.35	GO:0031514	motile cilium
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P27704|MK06_RAT
Mitogen-activated protein kinase 6
Search

MAPK6

0.97	Mitogen-activated protein kinase 6

0.79	GO:0000165	MAPK cascade
0.52	GO:0060999	positive regulation of dendritic spine development
0.46	GO:0071310	cellular response to organic substance
0.40	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0007049	cell cycle

0.81	GO:0004707	MAP kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0019901	protein kinase binding
0.48	GO:0046982	protein heterodimerization activity
0.38	GO:0042803	protein homodimerization activity

0.50	GO:0032156	septin cytoskeleton
0.46	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P27732|CAC1D_RAT
Voltage-dependent L-type calcium channel subunit alpha-1D
Search

CACNA1D

0.72	Voltage-dependent L-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.56	GO:0086046	membrane depolarization during SA node cell action potential
0.54	GO:0086002	cardiac muscle cell action potential involved in contraction
0.54	GO:0086091	regulation of heart rate by cardiac conduction
0.54	GO:0007605	sensory perception of sound
0.53	GO:0051928	positive regulation of calcium ion transport
0.53	GO:0070509	calcium ion import
0.51	GO:0043266	regulation of potassium ion transport
0.51	GO:0022898	regulation of transmembrane transporter activity

0.82	GO:0005245	voltage-gated calcium channel activity
0.54	GO:0051393	alpha-actinin binding
0.54	GO:0030506	ankyrin binding
0.36	GO:0030165	PDZ domain binding
0.35	GO:0046872	metal ion binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.54	GO:0030315	T-tubule
0.51	GO:0030018	Z disc
0.42	GO:0097470	ribbon synapse
0.42	GO:0009925	basal plasma membrane
0.37	GO:0032590	dendrite membrane
0.36	GO:0016324	apical plasma membrane
0.36	GO:0043025	neuronal cell body
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

sp|P27768|TNNI2_RAT
Troponin I, fast skeletal muscle
Search

TNNI2

0.92	Fast skeletal troponin I

0.54	GO:0003009	skeletal muscle contraction
0.46	GO:0060048	cardiac muscle contraction
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0090257	regulation of muscle system process
0.36	GO:0006887	exocytosis
0.35	GO:0030049	muscle filament sliding
0.34	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.33	GO:0048583	regulation of response to stimulus
0.32	GO:0007165	signal transduction

0.53	GO:0031014	troponin T binding
0.46	GO:0003779	actin binding
0.34	GO:0046872	metal ion binding
0.32	GO:0004871	signal transducer activity

0.84	GO:0005861	troponin complex
0.41	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P27775|IPKB_RAT
cAMP-dependent protein kinase inhibitor beta
Search

PKIB

0.96	cAMP-dependent protein kinase inhibitor beta

0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.57	GO:1904355	positive regulation of telomere capping
0.57	GO:0051973	positive regulation of telomerase activity
0.56	GO:0032212	positive regulation of telomere maintenance via telomerase
0.49	GO:0016310	phosphorylation
0.49	GO:2000479	regulation of cAMP-dependent protein kinase activity

0.86	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.51	GO:0016301	kinase activity
0.34	GO:0008289	lipid binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

sp|P27791|KAPCA_RAT
cAMP-dependent protein kinase catalytic subunit alpha
Search

PRKACA

0.82	cAMP-dependent protein kinase catalytic subunit alpha

0.63	GO:0006468	protein phosphorylation
0.59	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.56	GO:0001843	neural tube closure
0.56	GO:0070613	regulation of protein processing
0.51	GO:2000810	regulation of bicellular tight junction assembly
0.51	GO:0071374	cellular response to parathyroid hormone stimulus
0.50	GO:0048240	sperm capacitation
0.49	GO:0034605	cellular response to heat
0.49	GO:0071333	cellular response to glucose stimulus
0.49	GO:0071158	positive regulation of cell cycle arrest

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.52	GO:0034237	protein kinase A regulatory subunit binding
0.49	GO:0060089	molecular transducer activity
0.48	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.47	GO:0019901	protein kinase binding

0.57	GO:0097546	ciliary base
0.57	GO:0045171	intercellular bridge
0.53	GO:0005813	centrosome
0.51	GO:0005952	cAMP-dependent protein kinase complex
0.50	GO:0036126	sperm flagellum
0.50	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0001669	acrosomal vesicle
0.49	GO:0005829	cytosol
0.49	GO:0044853	plasma membrane raft
0.48	GO:0043197	dendritic spine

0.69

GO:0004674

sp|P27867|DHSO_RAT
Sorbitol dehydrogenase
Search

SORD

0.60	Sorbitol dehydrogenase

0.61	GO:0046370	fructose biosynthetic process
0.61	GO:0006062	sorbitol catabolic process
0.59	GO:0051160	L-xylitol catabolic process
0.55	GO:0030317	flagellated sperm motility
0.53	GO:0055114	oxidation-reduction process
0.38	GO:0046686	response to cadmium ion
0.38	GO:0046688	response to copper ion
0.37	GO:0006970	response to osmotic stress
0.37	GO:0031667	response to nutrient levels
0.37	GO:0009725	response to hormone

0.62	GO:0008270	zinc ion binding
0.58	GO:0003939	L-iditol 2-dehydrogenase activity
0.50	GO:0042802	identical protein binding
0.48	GO:0051287	NAD binding
0.39	GO:0046526	D-xylulose reductase activity
0.34	GO:0030246	carbohydrate binding
0.33	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.53	GO:0070062	extracellular exosome
0.53	GO:0031514	motile cilium
0.44	GO:0005739	mitochondrion
0.38	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.34	GO:0032991	macromolecular complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.58	EC:1.1.1.14	GO:0003939
0.39	KEGG:R01896	GO:0046526

sp|P27881|HXK2_RAT
Hexokinase-2
Search

0.38	Phosphotransferase

0.82	GO:0001678	cellular glucose homeostasis
0.74	GO:0046835	carbohydrate phosphorylation
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.30	GO:0050878	regulation of body fluid levels
0.30	GO:0019222	regulation of metabolic process
0.30	GO:0008104	protein localization
0.30	GO:0010827	regulation of glucose transport

0.83	GO:0005536	glucose binding
0.79	GO:0004396	hexokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane
0.30	GO:0044464	cell part
0.30	GO:0044422	organelle part

0.79

EC:2.7.1.1

GO:0004396

sp|P27926|HXK3_RAT
Hexokinase-3
Search

0.35	Phosphotransferase

0.82	GO:0001678	cellular glucose homeostasis
0.74	GO:0046835	carbohydrate phosphorylation
0.70	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.41	GO:0051156	glucose 6-phosphate metabolic process
0.30	GO:0010941	regulation of cell death
0.30	GO:0005996	monosaccharide metabolic process
0.30	GO:2001039	negative regulation of cellular response to drug

0.83	GO:0005536	glucose binding
0.79	GO:0004396	hexokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0019899	enzyme binding
0.30	GO:0042562	hormone binding

0.43	GO:0005739	mitochondrion
0.41	GO:0005829	cytosol
0.30	GO:0043234	protein complex

0.79

EC:2.7.1.1

GO:0004396

sp|P27952|RS2_RAT
40S ribosomal protein S2
Search

RPS2

0.51	Ribosomal protein S2

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.45	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.42	GO:0071353	cellular response to interleukin-4
0.36	GO:0045471	response to ethanol
0.36	GO:0000028	ribosomal small subunit assembly
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.48	GO:0017134	fibroblast growth factor binding
0.47	GO:0045296	cadherin binding
0.43	GO:0019899	enzyme binding
0.35	GO:0032403	protein complex binding

0.69	GO:0015935	small ribosomal subunit
0.48	GO:0022626	cytosolic ribosome
0.43	GO:0005654	nucleoplasm
0.38	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.36	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|P28023|DCTN1_RAT
Dynactin subunit 1
Search

DCTN1

0.86	Dynactin subunit 1

0.81	GO:0010970	transport along microtubule
0.56	GO:0090063	positive regulation of microtubule nucleation
0.55	GO:0051081	nuclear envelope disassembly
0.54	GO:0010457	centriole-centriole cohesion
0.54	GO:0032402	melanosome transport
0.53	GO:0034454	microtubule anchoring at centrosome
0.53	GO:0000132	establishment of mitotic spindle orientation
0.53	GO:0060236	regulation of mitotic spindle organization
0.52	GO:1905515	non-motile cilium assembly
0.50	GO:0042147	retrograde transport, endosome to Golgi

0.84	GO:0070840	dynein complex binding
0.49	GO:0019901	protein kinase binding
0.48	GO:0008017	microtubule binding
0.38	GO:0003774	motor activity
0.34	GO:0042802	identical protein binding

0.81	GO:0005869	dynactin complex
0.54	GO:0120103	centriolar subdistal appendage
0.54	GO:0035371	microtubule plus-end
0.52	GO:0099738	cell cortex region
0.52	GO:0005814	centriole
0.51	GO:0030904	retromer complex
0.50	GO:0005813	centrosome
0.50	GO:0031252	cell leading edge
0.50	GO:0000776	kinetochore
0.50	GO:0000922	spindle pole

sp|P28037|AL1L1_RAT
Cytosolic 10-formyltetrahydrofolate dehydrogenase
Search

ALDH1L1

0.91	Mitochondrial 10-formyltetrahydrofolate dehydrogenase

0.85	GO:0009258	10-formyltetrahydrofolate catabolic process
0.69	GO:0006730	one-carbon metabolic process
0.51	GO:0055114	oxidation-reduction process
0.48	GO:0009058	biosynthetic process
0.46	GO:0048885	neuromast deposition
0.44	GO:0048703	embryonic viscerocranium morphogenesis
0.44	GO:0001755	neural crest cell migration
0.43	GO:0007369	gastrulation
0.42	GO:0007507	heart development
0.36	GO:0046655	folic acid metabolic process

0.85	GO:0016155	formyltetrahydrofolate dehydrogenase activity
0.71	GO:0016742	hydroxymethyl-, formyl- and related transferase activity
0.67	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.35	GO:0016787	hydrolase activity
0.34	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.47	GO:0005737	cytoplasm
0.42	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0070062	extracellular exosome
0.33	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.85	EC:1.5.1.6	GO:0016155
0.85	KEGG:R00941	GO:0016155

sp|P28042|SSBP_RAT
Single-stranded DNA-binding protein, mitochondrial
Search

SSBP1

0.39	Single-stranded DNA-binding protein, mitochondrial

0.66	GO:0006260	DNA replication
0.58	GO:0051096	positive regulation of helicase activity
0.56	GO:0070584	mitochondrion morphogenesis
0.35	GO:0030968	endoplasmic reticulum unfolded protein response
0.34	GO:0050909	sensory perception of taste
0.34	GO:0006468	protein phosphorylation
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.73	GO:0003697	single-stranded DNA binding
0.52	GO:0003682	chromatin binding
0.35	GO:0035497	cAMP response element binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0003723	RNA binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0005515	protein binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0042645	mitochondrial nucleoid
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P28064|PSB8_RAT
Proteasome subunit beta type-8
Search

PSMB8

0.53	Proteasome subunit beta type

0.71	GO:0051603	proteolysis involved in cellular protein catabolic process
0.53	GO:0045444	fat cell differentiation
0.49	GO:0019882	antigen processing and presentation
0.49	GO:0052548	regulation of endopeptidase activity
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0060337	type I interferon signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.77	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.75	GO:0005839	proteasome core complex
0.61	GO:0005634	nucleus
0.55	GO:1990111	spermatoproteasome complex
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

sp|P28073|PSB6_RAT
Proteasome subunit beta type-6
Search

PSMB6

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.54	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.50	GO:0045296	cadherin binding

0.76	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome

sp|P28075|PSB5_RAT
Proteasome subunit beta type-5
Search

PSMB5

0.53	Proteasome subunit beta type

0.72	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.48	GO:0006979	response to oxidative stress
0.41	GO:0080129	proteasome core complex assembly
0.40	GO:0010499	proteasomal ubiquitin-independent protein catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.75	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.51	GO:0005813	centrosome
0.48	GO:0005737	cytoplasm
0.46	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome

sp|P28077|PSB9_RAT
Proteasome subunit beta type-9
Search

PSMB9

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.65	GO:0002376	immune system process
0.54	GO:2000116	regulation of cysteine-type endopeptidase activity
0.49	GO:0043632	modification-dependent macromolecule catabolic process
0.37	GO:0071347	cellular response to interleukin-1
0.36	GO:1901423	response to benzene
0.36	GO:0009628	response to abiotic stimulus
0.35	GO:0014889	muscle atrophy
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

0.77	GO:0004298	threonine-type endopeptidase activity
0.35	GO:0070628	proteasome binding
0.34	GO:0045296	cadherin binding

0.76	GO:0005839	proteasome core complex
0.59	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.44	GO:1990111	spermatoproteasome complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005773	vacuole
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

0.77

GO:0004298

sp|P28232|CXB5_RAT
Gap junction beta-5 protein
Search

GJB5

0.64	Gap junction protein beta 5

0.60	GO:0007154	cell communication
0.58	GO:0060708	spongiotrophoblast differentiation
0.56	GO:0060707	trophoblast giant cell differentiation
0.56	GO:0060713	labyrinthine layer morphogenesis
0.50	GO:0042048	olfactory behavior
0.46	GO:0007608	sensory perception of smell
0.42	GO:1905867	epididymis development
0.35	GO:0008544	epidermis development

0.83	GO:0005922	connexin complex
0.45	GO:0005730	nucleolus
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P28233|CXA6_RAT
Gap junction alpha-6 protein
Search

GJA1

0.64	Gap junction alpha-1 protein (Fragment)

0.77	GO:0007507	heart development
0.73	GO:0007267	cell-cell signaling
0.55	GO:0010644	cell communication by electrical coupling
0.54	GO:0055085	transmembrane transport
0.51	GO:0060156	milk ejection reflex
0.51	GO:0042246	tissue regeneration
0.51	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization
0.51	GO:0035107	appendage morphogenesis
0.51	GO:0010643	cell communication by chemical coupling
0.51	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization

0.59	GO:0005243	gap junction channel activity
0.48	GO:0097110	scaffold protein binding
0.48	GO:1990782	protein tyrosine kinase binding
0.47	GO:0048487	beta-tubulin binding
0.44	GO:0004871	signal transducer activity
0.44	GO:0005102	receptor binding
0.42	GO:0015075	ion transmembrane transporter activity
0.40	GO:0022832	voltage-gated channel activity
0.38	GO:0030165	PDZ domain binding
0.38	GO:0071253	connexin binding

0.83	GO:0005922	connexin complex
0.56	GO:0014704	intercalated disc
0.48	GO:0016328	lateral plasma membrane
0.47	GO:0005913	cell-cell adherens junction
0.47	GO:0016324	apical plasma membrane
0.46	GO:0043292	contractile fiber
0.46	GO:0005654	nucleoplasm
0.46	GO:0005882	intermediate filament
0.44	GO:0012505	endomembrane system
0.42	GO:0005739	mitochondrion

sp|P28234|CXA5_RAT
Gap junction alpha-5 protein
Search

GJA5

0.65	Gap junction alpha-5 protein (Fragment)

0.64	GO:0086044	atrial cardiac muscle cell to AV node cell communication by electrical coupling
0.63	GO:0086054	bundle of His cell to Purkinje myocyte communication by electrical coupling
0.63	GO:0098906	regulation of Purkinje myocyte action potential
0.63	GO:0098905	regulation of bundle of His cell action potential
0.63	GO:0098904	regulation of AV node cell action potential
0.63	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling
0.62	GO:0003193	pulmonary valve formation
0.62	GO:0098910	regulation of atrial cardiac muscle cell action potential
0.62	GO:0016264	gap junction assembly
0.62	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization

0.65	GO:0005243	gap junction channel activity
0.41	GO:0071253	connexin binding
0.41	GO:0097718	disordered domain specific binding

0.83	GO:0005922	connexin complex
0.59	GO:0014704	intercalated disc
0.49	GO:0005887	integral component of plasma membrane
0.37	GO:0042995	cell projection

sp|P28470|CANB2_RAT
Calcineurin subunit B type 2
Search

0.78	Calcineurin subunit B type

0.43	GO:0051531	NFAT protein import into nucleus
0.42	GO:0033173	calcineurin-NFAT signaling cascade
0.41	GO:0060487	lung epithelial cell differentiation
0.41	GO:0001569	branching involved in blood vessel morphogenesis
0.41	GO:0022011	myelination in peripheral nervous system
0.41	GO:0001837	epithelial to mesenchymal transition
0.40	GO:0007507	heart development
0.39	GO:0006470	protein dephosphorylation
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0007321	sperm displacement

0.70	GO:0005509	calcium ion binding
0.41	GO:0016018	cyclosporin A binding
0.39	GO:0004721	phosphoprotein phosphatase activity
0.38	GO:0019904	protein domain specific binding
0.35	GO:0019899	enzyme binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0005516	calmodulin binding

0.41	GO:0005955	calcineurin complex
0.41	GO:0042383	sarcolemma
0.37	GO:0005829	cytosol
0.34	GO:0000796	condensin complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.39

GO:0004721

sp|P28471|GBRA4_RAT
Gamma-aminobutyric acid receptor subunit alpha-4
Search

GABRA4

0.97	LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-4

0.80	GO:0007214	gamma-aminobutyric acid signaling pathway
0.72	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.60	GO:2001023	regulation of response to drug
0.56	GO:0007417	central nervous system development

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.40	GO:0005254	chloride channel activity
0.37	GO:0008503	benzodiazepine receptor activity

0.55	GO:0005886	plasma membrane
0.52	GO:1902711	GABA-A receptor complex
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.39	GO:0030054	cell junction

sp|P28473|GBRG3_RAT
Gamma-aminobutyric acid receptor subunit gamma-3
Search

0.94	Gamma-aminobutyric acid type A receptor epsilon subunit

0.81	GO:0007214	gamma-aminobutyric acid signaling pathway
0.72	GO:0006821	chloride transport
0.59	GO:0034220	ion transmembrane transport
0.37	GO:0042493	response to drug
0.36	GO:0007268	chemical synaptic transmission

0.80	GO:0004890	GABA-A receptor activity
0.72	GO:0005230	extracellular ligand-gated ion channel activity
0.40	GO:0005254	chloride channel activity
0.35	GO:0050811	GABA receptor binding

0.53	GO:0005886	plasma membrane
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.34	GO:0043235	receptor complex

sp|P28480|TCPA_RAT
T-complex protein 1 subunit alpha
Search

TCP1

0.77	T-complex protein 1 subunit alpha

0.65	GO:0006457	protein folding
0.61	GO:0044053	translocation of peptides or proteins into host cell cytoplasm
0.60	GO:0090670	RNA localization to Cajal body
0.59	GO:2000109	regulation of macrophage apoptotic process
0.59	GO:1904869	regulation of protein localization to Cajal body
0.59	GO:1904851	positive regulation of establishment of protein localization to telomere
0.58	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.57	GO:0051973	positive regulation of telomerase activity
0.57	GO:0007339	binding of sperm to zona pellucida
0.57	GO:0032212	positive regulation of telomere maintenance via telomerase

0.67	GO:0051082	unfolded protein binding
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0044183	protein binding involved in protein folding
0.34	GO:0003723	RNA binding
0.33	GO:0005216	ion channel activity

0.58	GO:0002199	zona pellucida receptor complex
0.58	GO:0005832	chaperonin-containing T-complex
0.57	GO:0000242	pericentriolar material
0.56	GO:0001669	acrosomal vesicle
0.56	GO:0005720	nuclear heterochromatin
0.55	GO:0043209	myelin sheath
0.54	GO:0044297	cell body
0.50	GO:0005874	microtubule
0.50	GO:0005794	Golgi apparatus
0.37	GO:0070062	extracellular exosome

sp|P28492|GLSL_RAT
Glutaminase liver isoform, mitochondrial
Search

GLS2

0.50	Glutaminase kidney

0.70	GO:0006541	glutamine metabolic process
0.55	GO:1903955	positive regulation of protein targeting to mitochondrion
0.52	GO:0006537	glutamate biosynthetic process
0.51	GO:0001967	suckling behavior
0.51	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.51	GO:0009065	glutamine family amino acid catabolic process
0.50	GO:0042981	regulation of apoptotic process
0.49	GO:0072593	reactive oxygen species metabolic process
0.49	GO:0051289	protein homotetramerization
0.47	GO:0007268	chemical synaptic transmission

0.77	GO:0004359	glutaminase activity
0.35	GO:0005515	protein binding

0.48	GO:0005739	mitochondrion
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol

0.77

EC:3.5.1.2

GO:0004359

sp|P28494|MA2A1_RAT
Alpha-mannosidase 2
Search

MAN2A1

0.47	Alpha-mannosidase

0.81	GO:0006013	mannose metabolic process
0.57	GO:0006491	N-glycan processing
0.56	GO:0007585	respiratory gaseous exchange
0.56	GO:0048286	lung alveolus development
0.55	GO:0060042	retina morphogenesis in camera-type eye
0.55	GO:0001889	liver development
0.53	GO:0050769	positive regulation of neurogenesis
0.52	GO:0007033	vacuole organization
0.52	GO:0006517	protein deglycosylation
0.52	GO:0001701	in utero embryonic development

0.79	GO:0004559	alpha-mannosidase activity
0.70	GO:0030246	carbohydrate binding
0.53	GO:0046872	metal ion binding
0.52	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds

0.57	GO:0005797	Golgi medial cisterna
0.53	GO:0005801	cis-Golgi network
0.52	GO:0000139	Golgi membrane
0.49	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.79

EC:3.2.1.24

GO:0004559

sp|P28564|5HT1B_RAT
5-hydroxytryptamine receptor 1B
Search

HTR1B

0.97	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

0.81	GO:0046849	bone remodeling
0.80	GO:0042310	vasoconstriction
0.80	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.79	GO:0050795	regulation of behavior
0.79	GO:0007631	feeding behavior
0.73	GO:0007268	chemical synaptic transmission
0.63	GO:0014063	negative regulation of serotonin secretion
0.61	GO:0071312	cellular response to alkaloid
0.59	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.59	GO:0071502	cellular response to temperature stimulus

0.80	GO:0099589	serotonin receptor activity
0.77	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.77	GO:0008227	G-protein coupled amine receptor activity
0.58	GO:0051378	serotonin binding
0.41	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.63	GO:0005887	integral component of plasma membrane
0.39	GO:0005737	cytoplasm

sp|P28565|5HT1D_RAT
5-hydroxytryptamine receptor 1D
Search

HTR1D

0.97	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled

0.85	GO:0042310	vasoconstriction
0.85	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.84	GO:0050795	regulation of behavior
0.78	GO:0007268	chemical synaptic transmission
0.76	GO:0006939	smooth muscle contraction
0.69	GO:0040012	regulation of locomotion
0.63	GO:0046849	bone remodeling
0.61	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.61	GO:0007631	feeding behavior
0.50	GO:0014063	negative regulation of serotonin secretion

0.85	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.61	GO:0051378	serotonin binding
0.37	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.36	GO:0005737	cytoplasm

sp|P28570|SC6A8_RAT
Sodium- and chloride-dependent creatine transporter 1
Search

SLC6A8

0.66	Sodium- and chloride-dependent creatine transporter 1

0.78	GO:1902598	creatine transmembrane transport
0.76	GO:0006836	neurotransmitter transport
0.51	GO:0006814	sodium ion transport
0.48	GO:1990403	embryonic brain development
0.44	GO:0015695	organic cation transport
0.44	GO:0015696	ammonium transport
0.43	GO:0006600	creatine metabolic process
0.41	GO:0006936	muscle contraction

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.78	GO:0005309	creatine:sodium symporter activity
0.47	GO:0015220	choline transmembrane transporter activity

0.58

GO:0005887

integral component of plasma membrane

sp|P28572|SC6A9_RAT
Sodium- and chloride-dependent glycine transporter 1
Search

SLC6A9

0.56	Solute carrier family 6 (neurotransmitter transporter, glycine), member 9

0.76	GO:0006836	neurotransmitter transport
0.69	GO:0003333	amino acid transmembrane transport
0.54	GO:0060092	regulation of synaptic transmission, glycinergic
0.53	GO:0015807	L-amino acid transport
0.52	GO:0007268	chemical synaptic transmission
0.52	GO:0015804	neutral amino acid transport
0.49	GO:0015893	drug transport
0.48	GO:0007626	locomotory behavior
0.47	GO:0060078	regulation of postsynaptic membrane potential
0.46	GO:0099643	signal release from synapse

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.73	GO:0005283	sodium:amino acid symporter activity
0.57	GO:0015187	glycine transmembrane transporter activity

0.63	GO:0005887	integral component of plasma membrane
0.52	GO:0044456	synapse part
0.44	GO:0097458	neuron part

sp|P28573|SC6A7_RAT
Sodium-dependent proline transporter
Search

SLC6A7

0.47	Sodium-dependent proline transporter

0.76	GO:0006836	neurotransmitter transport
0.56	GO:0035524	proline transmembrane transport
0.36	GO:0043092	L-amino acid import
0.35	GO:0089718	amino acid import across plasma membrane
0.35	GO:0042752	regulation of circadian rhythm
0.35	GO:1902475	L-alpha-amino acid transmembrane transport
0.34	GO:0015893	drug transport
0.34	GO:0001505	regulation of neurotransmitter levels
0.34	GO:0007275	multicellular organism development
0.33	GO:0060012	synaptic transmission, glycinergic

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.56	GO:0015193	L-proline transmembrane transporter activity
0.40	GO:0005283	sodium:amino acid symporter activity
0.37	GO:0015296	anion:cation symporter activity
0.36	GO:0015187	glycine transmembrane transporter activity
0.35	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity
0.34	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.33	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.33	GO:0003677	DNA binding

0.45	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

sp|P28576|PDGFA_RAT
Platelet-derived growth factor subunit A
Search

PDGFA

0.96	Platelet-derived growth factor alpha polypeptide b

0.74	GO:0010469	regulation of receptor activity
0.59	GO:1900238	regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
0.59	GO:2000591	positive regulation of metanephric mesenchymal cell migration
0.58	GO:0031954	positive regulation of protein autophosphorylation
0.57	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
0.57	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.57	GO:0010544	negative regulation of platelet activation
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.56	GO:0014910	regulation of smooth muscle cell migration
0.56	GO:0050919	negative chemotaxis

0.77	GO:0008083	growth factor activity
0.59	GO:0005161	platelet-derived growth factor receptor binding
0.56	GO:0048407	platelet-derived growth factor binding
0.54	GO:0005518	collagen binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.51	GO:0005615	extracellular space
0.51	GO:0009986	cell surface
0.39	GO:0005902	microvillus
0.36	GO:0031093	platelet alpha granule lumen
0.36	GO:0005796	Golgi lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0000139	Golgi membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P28646|SSR1_RAT
Somatostatin receptor type 1
Search

SSTR1

0.97	Somatostatin receptor type 1 subtype A

0.86	GO:0038169	somatostatin receptor signaling pathway
0.77	GO:0009755	hormone-mediated signaling pathway
0.55	GO:0007218	neuropeptide signaling pathway
0.54	GO:1990823	response to leukemia inhibitory factor
0.52	GO:0071345	cellular response to cytokine stimulus
0.51	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.51	GO:0007215	glutamate receptor signaling pathway
0.50	GO:0071392	cellular response to estradiol stimulus
0.48	GO:0008285	negative regulation of cell proliferation
0.44	GO:0071385	cellular response to glucocorticoid stimulus

0.86	GO:0004994	somatostatin receptor activity
0.53	GO:0042923	neuropeptide binding
0.43	GO:0030165	PDZ domain binding
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0017046	peptide hormone binding
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0004985	opioid receptor activity

0.48	GO:0043005	neuron projection
0.44	GO:0005886	plasma membrane
0.39	GO:0005829	cytosol
0.36	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

sp|P28647|AA3R_RAT
Adenosine receptor A3
Search

ADORA3

0.76	Adenosine receptor A3

0.85	GO:0001973	adenosine receptor signaling pathway
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0030336	negative regulation of cell migration
0.50	GO:0008285	negative regulation of cell proliferation
0.41	GO:0070255	regulation of mucus secretion
0.40	GO:0002441	histamine secretion involved in inflammatory response
0.40	GO:0043306	positive regulation of mast cell degranulation
0.39	GO:0043303	mast cell degranulation
0.39	GO:0002685	regulation of leukocyte migration
0.39	GO:0050727	regulation of inflammatory response

0.85

GO:0001609

G-protein coupled adenosine receptor activity

0.55	GO:0005886	plasma membrane
0.39	GO:0042629	mast cell granule
0.37	GO:0044456	synapse part
0.36	GO:0097458	neuron part
0.34	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

sp|P28648|CD63_RAT
CD63 antigen
Search

CD63

0.55	Tetraspanin

0.43	GO:0035188	hatching
0.42	GO:0007166	cell surface receptor signaling pathway
0.42	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.41	GO:0006461	protein complex assembly
0.41	GO:0050931	pigment cell differentiation
0.41	GO:0045807	positive regulation of endocytosis
0.40	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.40	GO:0043482	cellular pigment accumulation
0.40	GO:0002090	regulation of receptor internalization
0.40	GO:0016477	cell migration

0.46	GO:0003823	antigen binding
0.46	GO:0005178	integrin binding

0.44	GO:0031982	vesicle
0.41	GO:0031226	intrinsic component of plasma membrane
0.40	GO:0005764	lysosome
0.39	GO:0043230	extracellular organelle
0.38	GO:0012505	endomembrane system
0.38	GO:0098852	lytic vacuole membrane
0.38	GO:0009986	cell surface
0.37	GO:0005615	extracellular space
0.34	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

sp|P28818|RGRF1_RAT
Ras-specific guanine nucleotide-releasing factor 1
Search

RASGRF1

0.92	RAS protein-specific guanine nucleotide-releasing factor 1

0.78	GO:0035023	regulation of Rho protein signal transduction
0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.55	GO:0034976	response to endoplasmic reticulum stress
0.51	GO:0035020	regulation of Rac protein signal transduction
0.50	GO:1900449	regulation of glutamate receptor signaling pathway
0.50	GO:0048168	regulation of neuronal synaptic plasticity
0.48	GO:1904062	regulation of cation transmembrane transport
0.48	GO:0008283	cell proliferation
0.47	GO:0031175	neuron projection development

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.51	GO:0035254	glutamate receptor binding
0.35	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0005516	calmodulin binding
0.35	GO:0008022	protein C-terminus binding
0.35	GO:0005096	GTPase activator activity
0.34	GO:0008234	cysteine-type peptidase activity
0.31	GO:0004797	thymidine kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding

0.49	GO:0030426	growth cone
0.45	GO:0005622	intracellular
0.42	GO:0012505	endomembrane system
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0097440	apical dendrite
0.36	GO:0016327	apicolateral plasma membrane
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0043025	neuronal cell body
0.33	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.34

GO:0008234

sp|P28826|MEP1B_RAT
Meprin A subunit beta
Search

MEP1B

0.89	Meprin A subunit beta

0.63	GO:1901998	toxin transport
0.61	GO:0006508	proteolysis
0.42	GO:0006954	inflammatory response
0.37	GO:0007586	digestion

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.59	GO:0042802	identical protein binding
0.34	GO:0005509	calcium ion binding

0.39	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

sp|P28840|NEC1_RAT
Neuroendocrine convertase 1
Search

PCSK1

0.96	Proprotein convertase subtilisin kexin type 1 variant 1

0.61	GO:0006508	proteolysis
0.51	GO:0042445	hormone metabolic process
0.50	GO:0051604	protein maturation
0.44	GO:0043043	peptide biosynthetic process
0.36	GO:0010157	response to chlorate
0.36	GO:0043278	response to morphine
0.36	GO:0048678	response to axon injury
0.36	GO:0021983	pituitary gland development
0.35	GO:0070542	response to fatty acid
0.35	GO:0051384	response to glucocorticoid

0.69	GO:0004252	serine-type endopeptidase activity
0.50	GO:0042802	identical protein binding
0.36	GO:0043559	insulin binding
0.35	GO:0051087	chaperone binding
0.34	GO:0032403	protein complex binding

0.52	GO:0005615	extracellular space
0.40	GO:0030133	transport vesicle
0.39	GO:0034774	secretory granule lumen
0.35	GO:0043204	perikaryon
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0043679	axon terminus
0.35	GO:0030425	dendrite
0.35	GO:0005802	trans-Golgi network
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P28841|NEC2_RAT
Neuroendocrine convertase 2
Search

PCSK2

0.95	Proprotein convertase subtilisin kexin type 2 variant 1

0.59	GO:0034230	enkephalin processing
0.59	GO:0030070	insulin processing
0.55	GO:0016540	protein autoprocessing
0.50	GO:0007399	nervous system development
0.41	GO:0034231	islet amyloid polypeptide processing

0.67	GO:0004252	serine-type endopeptidase activity
0.37	GO:0032403	protein complex binding

0.51	GO:0005615	extracellular space
0.45	GO:0005634	nucleus
0.40	GO:0030133	transport vesicle
0.39	GO:0034774	secretory granule lumen
0.39	GO:0043204	perikaryon
0.38	GO:0030425	dendrite
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0004252

sp|P28902|GUC2A_RAT
Guanylin
Search

GUCA2A

0.97	Preprouroguanylin

0.86	GO:0031284	positive regulation of guanylate cyclase activity
0.39	GO:0007586	digestion
0.38	GO:0010469	regulation of receptor activity

0.86	GO:0030250	guanylate cyclase activator activity
0.38	GO:0005179	hormone activity

0.66	GO:0005576	extracellular region
0.41	GO:0031982	vesicle

sp|P29066|ARRB1_RAT
Beta-arrestin-1
Search

ARRB1

0.95	Beta-arrestin-1

0.61	GO:0007165	signal transduction
0.57	GO:0045746	negative regulation of Notch signaling pathway
0.55	GO:0043393	regulation of protein binding
0.54	GO:0090240	positive regulation of histone H4 acetylation
0.54	GO:0002031	G-protein coupled receptor internalization
0.54	GO:0002092	positive regulation of receptor internalization
0.54	GO:0032717	negative regulation of interleukin-8 production
0.54	GO:0043149	stress fiber assembly
0.53	GO:0032715	negative regulation of interleukin-6 production
0.53	GO:0035025	positive regulation of Rho protein signal transduction

0.55	GO:1990763	arrestin family protein binding
0.55	GO:0031701	angiotensin receptor binding
0.54	GO:0031434	mitogen-activated protein kinase kinase binding
0.53	GO:0005159	insulin-like growth factor receptor binding
0.53	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.49	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0005096	GTPase activator activity
0.48	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0008134	transcription factor binding
0.40	GO:0035612	AP-2 adaptor complex binding

0.54	GO:0031143	pseudopodium
0.49	GO:0016604	nuclear body
0.47	GO:0031410	cytoplasmic vesicle
0.47	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.40	GO:0005905	clathrin-coated pit
0.38	GO:0043197	dendritic spine
0.38	GO:0014069	postsynaptic density
0.38	GO:0016323	basolateral plasma membrane
0.37	GO:0045211	postsynaptic membrane

0.36

EC:2.3.1.48

GO:0004402

sp|P29067|ARRB2_RAT
Beta-arrestin-2
Search

ARRB2

0.97	Beta arrestin 2 variant 4

0.61	GO:0007165	signal transduction
0.53	GO:0043393	regulation of protein binding
0.53	GO:0002031	G-protein coupled receptor internalization
0.53	GO:0032226	positive regulation of synaptic transmission, dopaminergic
0.53	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.52	GO:0002092	positive regulation of receptor internalization
0.52	GO:0032691	negative regulation of interleukin-1 beta production
0.52	GO:0032695	negative regulation of interleukin-12 production
0.52	GO:2000727	positive regulation of cardiac muscle cell differentiation
0.51	GO:0034122	negative regulation of toll-like receptor signaling pathway

0.52	GO:0031701	angiotensin receptor binding
0.52	GO:0043422	protein kinase B binding
0.48	GO:0032947	protein complex scaffold activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0031859	platelet activating factor receptor binding
0.42	GO:0031691	alpha-1A adrenergic receptor binding
0.41	GO:0031692	alpha-1B adrenergic receptor binding
0.41	GO:0031762	follicle-stimulating hormone receptor binding
0.41	GO:0031826	type 2A serotonin receptor binding
0.41	GO:0031748	D1 dopamine receptor binding

0.49	GO:0030139	endocytic vesicle
0.42	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.39	GO:0005905	clathrin-coated pit
0.39	GO:0043197	dendritic spine
0.39	GO:0014069	postsynaptic density
0.35	GO:0005829	cytosol

sp|P29089|AGTRB_RAT
Type-1B angiotensin II receptor
Search

AGTR1

0.97	type-1 angiotensin II receptor

0.84	GO:0038166	angiotensin-activated signaling pathway
0.82	GO:0019229	regulation of vasoconstriction
0.42	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.42	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.41	GO:0042756	drinking behavior
0.41	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure
0.41	GO:0071549	cellular response to dexamethasone stimulus
0.41	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.41	GO:0045777	positive regulation of blood pressure

0.85	GO:0004945	angiotensin type II receptor activity
0.44	GO:0001596	angiotensin type I receptor activity
0.40	GO:0031711	bradykinin receptor binding
0.40	GO:0017046	peptide hormone binding
0.40	GO:0043621	protein self-association
0.38	GO:0031748	D1 dopamine receptor binding
0.37	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0019901	protein kinase binding

0.40	GO:0031983	vesicle lumen
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0012506	vesicle membrane
0.37	GO:0055037	recycling endosome
0.37	GO:0030425	dendrite
0.36	GO:0031968	organelle outer membrane
0.35	GO:0005794	Golgi apparatus
0.34	GO:0005887	integral component of plasma membrane

sp|P29101|SYT2_RAT
Synaptotagmin-2
Search

SYT2

0.84	Synaptotagmin IIa

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.67	GO:1903861	positive regulation of dendrite extension
0.58	GO:0017158	regulation of calcium ion-dependent exocytosis
0.56	GO:0017156	calcium ion regulated exocytosis
0.56	GO:0097479	synaptic vesicle localization
0.56	GO:0099003	vesicle-mediated transport in synapse

0.81	GO:0005544	calcium-dependent phospholipid binding
0.56	GO:0019905	syntaxin binding
0.54	GO:0050750	low-density lipoprotein particle receptor binding
0.52	GO:0048306	calcium-dependent protein binding
0.50	GO:0030276	clathrin binding
0.50	GO:0005509	calcium ion binding
0.45	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.41	GO:0001786	phosphatidylserine binding
0.39	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding
0.39	GO:0005516	calmodulin binding

0.82	GO:0008021	synaptic vesicle
0.59	GO:0099501	exocytic vesicle membrane
0.53	GO:0031045	dense core granule
0.52	GO:0042734	presynaptic membrane
0.50	GO:0030424	axon
0.46	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.45	GO:0042584	chromaffin granule membrane
0.41	GO:0030054	cell junction
0.40	GO:0043679	axon terminus

sp|P29117|PPIF_RAT
Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Search

PPIF

0.49	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.57	GO:0010849	regulation of proton-transporting ATPase activity, rotational mechanism
0.57	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity
0.56	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.56	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death
0.56	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
0.56	GO:0090324	negative regulation of oxidative phosphorylation
0.55	GO:0070301	cellular response to hydrogen peroxide
0.54	GO:0071243	cellular response to arsenic-containing substance

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.41	GO:0016018	cyclosporin A binding
0.37	GO:0043424	protein histidine kinase binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005757	mitochondrial permeability transition pore complex
0.42	GO:0005759	mitochondrial matrix
0.38	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.37	GO:0009533	chloroplast stromal thylakoid
0.36	GO:0031977	thylakoid lumen
0.35	GO:0009535	chloroplast thylakoid membrane
0.33	GO:0005750	mitochondrial respiratory chain complex III

0.72

EC:5.2.1.8

GO:0003755

sp|P29147|BDH_RAT
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
Search

BDH1

0.48	D-beta-hydroxybutyrate dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.36	GO:0051412	response to corticosterone
0.36	GO:0060612	adipose tissue development
0.35	GO:0060416	response to growth hormone
0.35	GO:0032355	response to estradiol
0.35	GO:0046951	ketone body biosynthetic process
0.35	GO:0045471	response to ethanol
0.35	GO:0001889	liver development
0.35	GO:0046686	response to cadmium ion
0.35	GO:0032868	response to insulin

0.54	GO:0016491	oxidoreductase activity
0.34	GO:0005543	phospholipid binding

0.47	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.44	GO:0019866	organelle inner membrane
0.42	GO:0098576	lumenal side of membrane
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

sp|P29188|NEUAX_RAT
Putative N-acylneuraminate cytidylyltransferase (Fragment)
Search

0.94	Putative N-acylneuraminate cytidylyltransferase (Fragment)

0.80

GO:0006054

N-acetylneuraminate metabolic process

0.85

GO:0008781

N-acylneuraminate cytidylyltransferase activity

0.61

GO:0005634

nucleus

0.85

EC:2.7.7.43

GO:0008781

sp|P29266|3HIDH_RAT
3-hydroxyisobutyrate dehydrogenase, mitochondrial
Search

HIBADH

0.54	3-hydroxyisobutyrate dehydrogenase, mitochondrial

0.78	GO:0006574	valine catabolic process
0.53	GO:0055114	oxidation-reduction process

0.81	GO:0008442	3-hydroxyisobutyrate dehydrogenase activity
0.76	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.67	GO:0051287	NAD binding

0.43	GO:0005739	mitochondrion
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:1.1.1.31

GO:0008442

sp|P29276|AA2BR_RAT
Adenosine receptor A2b
Search

ADORA2B

0.92	Adenosine receptor A2

0.85	GO:0001973	adenosine receptor signaling pathway
0.56	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.56	GO:0002880	regulation of chronic inflammatory response to non-antigenic stimulus
0.54	GO:0002678	positive regulation of chronic inflammatory response
0.54	GO:0060087	relaxation of vascular smooth muscle
0.54	GO:0033008	positive regulation of mast cell activation involved in immune response
0.53	GO:0043302	positive regulation of leukocyte degranulation
0.53	GO:0002888	positive regulation of myeloid leukocyte mediated immunity
0.53	GO:0031284	positive regulation of guanylate cyclase activity
0.53	GO:0043304	regulation of mast cell degranulation

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.42	GO:0042802	identical protein binding
0.41	GO:0019899	enzyme binding
0.37	GO:0031802	type 5 metabotropic glutamate receptor binding
0.36	GO:0051393	alpha-actinin binding
0.35	GO:0046982	protein heterodimerization activity

0.55	GO:0005886	plasma membrane
0.43	GO:0098794	postsynapse
0.37	GO:0005622	intracellular
0.36	GO:0044304	main axon
0.36	GO:0032279	asymmetric synapse
0.36	GO:0048786	presynaptic active zone
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0031252	cell leading edge
0.35	GO:0009986	cell surface

sp|P29288|PPA5_RAT
Tartrate-resistant acid phosphatase type 5
Search

ACP5

0.89	Tartrate-resistant acid phosphatase type 5

0.59	GO:0016311	dephosphorylation
0.58	GO:0032929	negative regulation of superoxide anion generation
0.56	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.56	GO:0032691	negative regulation of interleukin-1 beta production
0.56	GO:0032695	negative regulation of interleukin-12 production
0.56	GO:0045453	bone resorption
0.55	GO:0032720	negative regulation of tumor necrosis factor production
0.54	GO:0060349	bone morphogenesis
0.54	GO:0050728	negative regulation of inflammatory response
0.54	GO:0050830	defense response to Gram-positive bacterium

0.67	GO:0003993	acid phosphatase activity
0.58	GO:0008198	ferrous iron binding
0.57	GO:0008199	ferric iron binding
0.33	GO:0003723	RNA binding

0.52	GO:0005764	lysosome
0.38	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.67

EC:3.1.3.2

GO:0003993

sp|P29293|ACRO_RAT
Acrosin
Search

ACR

0.97

Acrosin-b

0.60	GO:0006508	proteolysis
0.57	GO:0007190	activation of adenylate cyclase activity
0.57	GO:0007340	acrosome reaction
0.55	GO:0007341	penetration of zona pellucida
0.53	GO:0007339	binding of sperm to zona pellucida
0.39	GO:0048545	response to steroid hormone
0.37	GO:0006898	receptor-mediated endocytosis
0.36	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.35	GO:0007306	eggshell chorion assembly
0.34	GO:0044257	cellular protein catabolic process

0.68	GO:0004252	serine-type endopeptidase activity
0.56	GO:0005537	mannose binding
0.45	GO:0042806	fucose binding
0.42	GO:0004040	amidase activity
0.39	GO:0005044	scavenger receptor activity
0.37	GO:0008144	drug binding
0.36	GO:0005515	protein binding
0.36	GO:0005507	copper ion binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0005509	calcium ion binding

0.81	GO:0001669	acrosomal vesicle
0.45	GO:0044437	vacuolar part
0.44	GO:0044433	cytoplasmic vesicle part
0.43	GO:0043234	protein complex
0.39	GO:0005798	Golgi-associated vesicle
0.35	GO:0005634	nucleus
0.35	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.68

GO:0004252

sp|P29314|RS9_RAT
40S ribosomal protein S9
Search

RPS9

0.45	Ribosomal protein S9 (Predicted)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0045903	positive regulation of translational fidelity
0.48	GO:0008284	positive regulation of cell proliferation
0.35	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0034660	ncRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0045182	translation regulator activity
0.36	GO:0000213	tRNA-intron endonuclease activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.70	GO:0015935	small ribosomal subunit
0.50	GO:0022626	cytosolic ribosome
0.46	GO:0005730	nucleolus
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0000228	nuclear chromosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.1.27.9

GO:0000213

sp|P29315|RINI_RAT
Ribonuclease inhibitor
Search

RNH1

0.77	Ribonuclease inhibitor

0.72	GO:0045765	regulation of angiogenesis
0.64	GO:0043086	negative regulation of catalytic activity
0.39	GO:0006954	inflammatory response
0.38	GO:0042981	regulation of apoptotic process
0.38	GO:0006402	mRNA catabolic process
0.38	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.37	GO:0045087	innate immune response
0.37	GO:1904784	NLRP1 inflammasome complex assembly
0.37	GO:0043068	positive regulation of programmed cell death
0.36	GO:0002674	negative regulation of acute inflammatory response

0.72	GO:0008428	ribonuclease inhibitor activity
0.39	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0016874	ligase activity

0.82	GO:0032311	angiogenin-PRI complex
0.64	GO:0005654	nucleoplasm
0.63	GO:0005829	cytosol
0.43	GO:0070062	extracellular exosome

0.32

GO:0016874

sp|P29321|EPHA8_RAT
Ephrin type-A receptor 8 (Fragment)
Search

0.94	Ephrin type-A receptor 8 (Fragment)

0.81	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.45	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.44	GO:0006929	substrate-dependent cell migration
0.44	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.44	GO:0016322	neuron remodeling
0.44	GO:0033628	regulation of cell adhesion mediated by integrin
0.42	GO:0046777	protein autophosphorylation
0.42	GO:0007411	axon guidance
0.42	GO:0043410	positive regulation of MAPK cascade

0.84	GO:0005004	GPI-linked ephrin receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.61	GO:0005887	integral component of plasma membrane
0.42	GO:0031901	early endosome membrane
0.42	GO:0043005	neuron projection

sp|P29348|GNAT3_RAT
Guanine nucleotide-binding protein G(t) subunit alpha-3
Search

GNAT3

0.97	Guanine nucleotide-binding protein Gt subunit alpha-X

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.63	GO:0050917	sensory perception of umami taste
0.60	GO:0050913	sensory perception of bitter taste
0.59	GO:0050908	detection of light stimulus involved in visual perception
0.57	GO:0050916	sensory perception of sweet taste
0.57	GO:0042462	eye photoreceptor cell development
0.56	GO:0060041	retina development in camera-type eye
0.54	GO:0007602	phototransduction
0.52	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.51	GO:0048593	camera-type eye morphogenesis

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0001664	G-protein coupled receptor binding
0.36	GO:0000035	acyl binding
0.36	GO:0046872	metal ion binding

0.62	GO:0001917	photoreceptor inner segment
0.61	GO:0001750	photoreceptor outer segment
0.51	GO:1905360	GTPase complex
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.47	GO:0043234	protein complex
0.47	GO:0032391	photoreceptor connecting cilium
0.42	GO:0098590	plasma membrane region
0.41	GO:0045177	apical part of cell
0.39	GO:0005737	cytoplasm
0.39	GO:0097223	sperm part

sp|P29410|KAD2_RAT
Adenylate kinase 2, mitochondrial
Search

AK2

0.58	Adenylate kinase 2, mitochondrial

0.75	GO:0006172	ADP biosynthetic process
0.68	GO:0046939	nucleotide phosphorylation
0.63	GO:0046033	AMP metabolic process
0.54	GO:0046034	ATP metabolic process
0.44	GO:0060218	hematopoietic stem cell differentiation
0.42	GO:0002521	leukocyte differentiation
0.36	GO:0046060	dATP metabolic process
0.35	GO:0097066	response to thyroid hormone
0.35	GO:0015949	nucleobase-containing small molecule interconversion
0.35	GO:0001889	liver development

0.77	GO:0004017	adenylate kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:0005758	mitochondrial intermembrane space
0.55	GO:0097226	sperm mitochondrial sheath
0.42	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.38	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

0.77

EC:2.7.4.3

GO:0004017

sp|P29411|KAD3_RAT
GTP:AMP phosphotransferase AK3, mitochondrial
Search

AK3

0.97	Adenylate kinase 3

0.75	GO:0046041	ITP metabolic process
0.74	GO:0006172	ADP biosynthetic process
0.69	GO:0046939	nucleotide phosphorylation
0.69	GO:0046039	GTP metabolic process
0.68	GO:0046033	AMP metabolic process
0.54	GO:0046051	UTP metabolic process
0.41	GO:0061515	myeloid cell development
0.40	GO:0046034	ATP metabolic process
0.40	GO:0032261	purine nucleotide salvage
0.37	GO:0009142	nucleoside triphosphate biosynthetic process

0.79	GO:0046899	nucleoside triphosphate adenylate kinase activity
0.78	GO:0004017	adenylate kinase activity
0.58	GO:0032550	purine ribonucleoside binding
0.58	GO:0019001	guanyl nucleotide binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0004550	nucleoside diphosphate kinase activity
0.36	GO:0008270	zinc ion binding

0.68	GO:0005759	mitochondrial matrix
0.35	GO:0005758	mitochondrial intermembrane space
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

0.79

EC:2.7.4.10

GO:0046899

sp|P29414|CXA3_RAT
Gap junction alpha-3 protein
Search

GJA3

0.64	Gap junction protein (Fragment)

0.73	GO:0007601	visual perception
0.60	GO:0007154	cell communication
0.52	GO:0055085	transmembrane transport
0.46	GO:0048050	post-embryonic eye morphogenesis
0.45	GO:0003161	cardiac conduction system development
0.44	GO:0055008	cardiac muscle tissue morphogenesis
0.44	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.43	GO:0008016	regulation of heart contraction
0.36	GO:0042542	response to hydrogen peroxide
0.36	GO:0009268	response to pH

0.83	GO:0005243	gap junction channel activity
0.35	GO:0042802	identical protein binding

0.84	GO:0005922	connexin complex
0.36	GO:0045121	membrane raft
0.33	GO:0005887	integral component of plasma membrane

sp|P29418|ATP5E_RAT
ATP synthase subunit epsilon, mitochondrial
Search

ATP5E

0.88	ATP synthase subunit epsilonserine-threonine

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0042407	cristae formation
0.37	GO:0006839	mitochondrial transport
0.35	GO:0046907	intracellular transport

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.37	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism

0.84	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.36	GO:0005759	mitochondrial matrix

0.37

EC:3.6.3.6

GO:0008553

sp|P29419|ATP5I_RAT
ATP synthase subunit e, mitochondrial
Search

ATP5I

0.83	Mitochondrial ATP synthase subunit e

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.36	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.35	GO:0001666	response to hypoxia
0.35	GO:0032570	response to progesterone
0.35	GO:0043627	response to estrogen
0.34	GO:0046907	intracellular transport
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.46	GO:0016887	ATPase activity
0.39	GO:0033142	progesterone receptor binding
0.37	GO:0031490	chromatin DNA binding
0.37	GO:0047624	adenosine-tetraphosphatase activity
0.35	GO:0008013	beta-catenin binding
0.33	GO:0022853	active ion transmembrane transporter activity
0.33	GO:0015399	primary active transmembrane transporter activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.36	GO:0000790	nuclear chromatin
0.36	GO:0032993	protein-DNA complex
0.34	GO:0016363	nuclear matrix
0.30	GO:0016021	integral component of membrane

0.46

GO:0016887

sp|P29456|IL10_RAT
Interleukin-10
Search

IL10

0.92	Interleukin-10

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.63	GO:0002904	positive regulation of B cell apoptotic process
0.63	GO:0032800	receptor biosynthetic process
0.63	GO:0002740	negative regulation of cytokine secretion involved in immune response
0.62	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.62	GO:0030889	negative regulation of B cell proliferation
0.62	GO:0032715	negative regulation of interleukin-6 production
0.60	GO:0051384	response to glucocorticoid
0.59	GO:0050715	positive regulation of cytokine secretion

0.80	GO:0005125	cytokine activity
0.45	GO:0005141	interleukin-10 receptor binding
0.34	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

sp|P29457|SERPH_RAT
Serpin H1
Search

SERPINH1

0.97	Serpin peptidase inhibitor clade H member 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.58	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis
0.57	GO:0032964	collagen biosynthetic process
0.57	GO:0030199	collagen fibril organization
0.49	GO:0051604	protein maturation
0.45	GO:0031101	fin regeneration
0.35	GO:0006986	response to unfolded protein

0.83	GO:0005518	collagen binding
0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.48	GO:0051082	unfolded protein binding
0.34	GO:0003723	RNA binding

0.73	GO:0005615	extracellular space
0.56	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.54	GO:0045121	membrane raft
0.53	GO:0005783	endoplasmic reticulum
0.40	GO:0005581	collagen trimer
0.38	GO:0043233	organelle lumen
0.37	GO:1903561	extracellular vesicle
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P29476|NOS1_RAT
Nitric oxide synthase, brain
Search

NOS1

0.72	Neuronal nitric oxide synthase

0.84	GO:0006809	nitric oxide biosynthetic process
0.57	GO:0098924	retrograde trans-synaptic signaling by nitric oxide
0.57	GO:1901206	positive regulation of adrenergic receptor signaling pathway involved in heart process
0.57	GO:0051612	negative regulation of serotonin uptake
0.56	GO:0097755	positive regulation of blood vessel diameter
0.56	GO:0042738	exogenous drug catabolic process
0.56	GO:0098735	positive regulation of the force of heart contraction
0.56	GO:0018119	peptidyl-cysteine S-nitrosylation
0.55	GO:0007263	nitric oxide mediated signal transduction
0.54	GO:0043267	negative regulation of potassium ion transport

0.84	GO:0004517	nitric-oxide synthase activity
0.77	GO:0005516	calmodulin binding
0.70	GO:0010181	FMN binding
0.68	GO:0050661	NADP binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.62	GO:0020037	heme binding
0.62	GO:0005506	iron ion binding
0.47	GO:0003958	NADPH-hemoprotein reductase activity
0.38	GO:0046870	cadmium ion binding
0.38	GO:0017080	sodium channel regulator activity

0.54	GO:0030315	T-tubule
0.53	GO:0033017	sarcoplasmic reticulum membrane
0.52	GO:0005901	caveola
0.52	GO:0030018	Z disc
0.49	GO:0045202	synapse
0.47	GO:0005654	nucleoplasm
0.46	GO:0005856	cytoskeleton
0.43	GO:0005739	mitochondrion
0.40	GO:0044309	neuron spine
0.40	GO:0036477	somatodendritic compartment

0.84

EC:1.14.13.39

GO:0004517

sp|P29524|PAI2_RAT
Plasminogen activator inhibitor 2 type A
Search

SERPINB2

0.84	Leukocyte elastase inhibitor

0.69	GO:0010951	negative regulation of endopeptidase activity
0.65	GO:0043066	negative regulation of apoptotic process
0.41	GO:0042060	wound healing
0.39	GO:0030193	regulation of blood coagulation
0.38	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.38	GO:2000257	regulation of protein activation cascade
0.37	GO:0043627	response to estrogen
0.37	GO:0090136	epithelial cell-cell adhesion
0.37	GO:0002444	myeloid leukocyte mediated immunity
0.36	GO:0035722	interleukin-12-mediated signaling pathway

0.71	GO:0004867	serine-type endopeptidase inhibitor activity
0.39	GO:0002020	protease binding
0.38	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.37	GO:0008201	heparin binding
0.36	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process
0.33	GO:0042802	identical protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.37	GO:0005829	cytosol
0.35	GO:0012505	endomembrane system
0.35	GO:0097180	serine protease inhibitor complex
0.34	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0032010	phagolysosome
0.34	GO:1903561	extracellular vesicle
0.34	GO:0099503	secretory vesicle

0.32

GO:0008233

sp|P29534|VCAM1_RAT
Vascular cell adhesion protein 1
Search

0.64	Vascular cell adhesion molecule

0.77	GO:0098609	cell-cell adhesion
0.30	GO:0060711	labyrinthine layer development
0.30	GO:0051251	positive regulation of lymphocyte activation
0.30	GO:0050670	regulation of lymphocyte proliferation
0.30	GO:0071331	cellular response to hexose stimulus
0.30	GO:0040011	locomotion
0.30	GO:0070482	response to oxygen levels
0.30	GO:0016032	viral process
0.30	GO:0032496	response to lipopolysaccharide
0.30	GO:0022409	positive regulation of cell-cell adhesion

0.30	GO:0050839	cell adhesion molecule binding
0.30	GO:0032403	protein complex binding
0.30	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors
0.30	GO:0005102	receptor binding

0.30	GO:0045177	apical part of cell
0.30	GO:0043234	protein complex
0.30	GO:0009986	cell surface
0.30	GO:0044459	plasma membrane part
0.30	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane
0.30	GO:0005769	early endosome
0.30	GO:0120025	plasma membrane bounded cell projection
0.30	GO:0005783	endoplasmic reticulum
0.30	GO:0043230	extracellular organelle

0.30

EC:1.4

GO:0016638

sp|P29596|ATF3_RAT
Cyclic AMP-dependent transcription factor ATF-3
Search

ATF3

0.97	Cyclic AMP-dependent transcription factor ATF-3

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.58	GO:0035914	skeletal muscle cell differentiation
0.58	GO:0034198	cellular response to amino acid starvation
0.58	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.57	GO:0030968	endoplasmic reticulum unfolded protein response
0.57	GO:0043620	regulation of DNA-templated transcription in response to stress
0.52	GO:0045892	negative regulation of transcription, DNA-templated
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0019319	hexose biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.37	GO:0003682	chromatin binding
0.35	GO:0003714	transcription corepressor activity

0.62	GO:1990622	CHOP-ATF3 complex
0.60	GO:0005634	nucleus
0.49	GO:0043233	organelle lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.37	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|P29598|UROK_RAT
Urokinase-type plasminogen activator
Search

PLAU

0.97	Urokinase-type plasminogen activator

0.80	GO:0031639	plasminogen activation
0.66	GO:2000097	regulation of smooth muscle cell-matrix adhesion
0.65	GO:0014909	smooth muscle cell migration
0.64	GO:0042730	fibrinolysis
0.63	GO:0014910	regulation of smooth muscle cell migration
0.63	GO:0033628	regulation of cell adhesion mediated by integrin
0.59	GO:0001666	response to hypoxia
0.59	GO:0030335	positive regulation of cell migration
0.56	GO:0042127	regulation of cell proliferation
0.56	GO:0010469	regulation of receptor activity

0.69	GO:0004252	serine-type endopeptidase activity
0.50	GO:0016301	kinase activity
0.37	GO:0090729	toxin activity
0.35	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0005044	scavenger receptor activity
0.32	GO:0005057	signal transducer activity, downstream of receptor
0.32	GO:0004222	metalloendopeptidase activity
0.31	GO:0008270	zinc ion binding

0.62	GO:0005576	extracellular region
0.56	GO:0009986	cell surface
0.38	GO:0005925	focal adhesion
0.38	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.35	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0044444	cytoplasmic part
0.34	GO:0043229	intracellular organelle
0.34	GO:0097223	sperm part

0.69

GO:0004252

sp|P29676|EPO_RAT
Erythropoietin
Search

EPO

0.97	Erythropoietin

0.84	GO:0043249	erythrocyte maturation
0.76	GO:0010469	regulation of receptor activity
0.75	GO:0038162	erythropoietin-mediated signaling pathway
0.73	GO:1902250	regulation of erythrocyte apoptotic process
0.70	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.70	GO:0033033	negative regulation of myeloid cell apoptotic process
0.68	GO:0042541	hemoglobin biosynthetic process
0.67	GO:0010523	negative regulation of calcium ion transport into cytosol
0.67	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.67	GO:2001258	negative regulation of cation channel activity

0.87	GO:0005128	erythropoietin receptor binding
0.79	GO:0005179	hormone activity
0.63	GO:0030295	protein kinase activator activity
0.62	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.59	GO:0009986	cell surface
0.45	GO:0044297	cell body
0.30	GO:0016020	membrane

sp|P29826|HB2B_RAT
Rano class II histocompatibility antigen, B-1 beta chain
Search

0.42	MHC class II histocompatibility antigen, DQ beta chain

0.82	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.46	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.44	GO:0002377	immunoglobulin production
0.44	GO:0002449	lymphocyte mediated immunity
0.41	GO:0002343	peripheral B cell selection
0.40	GO:0002579	positive regulation of antigen processing and presentation
0.40	GO:0002827	positive regulation of T-helper 1 type immune response
0.40	GO:0046635	positive regulation of alpha-beta T cell activation
0.39	GO:0071345	cellular response to cytokine stimulus

0.46	GO:0042605	peptide antigen binding
0.41	GO:1990405	protein antigen binding
0.39	GO:0015643	toxic substance binding
0.38	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0008134	transcription factor binding
0.35	GO:0032395	MHC class II receptor activity
0.34	GO:0046982	protein heterodimerization activity

0.75	GO:0042613	MHC class II protein complex
0.44	GO:0005771	multivesicular body
0.43	GO:0009897	external side of plasma membrane
0.42	GO:0005769	early endosome
0.41	GO:0005794	Golgi apparatus
0.35	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.34	GO:0030669	clathrin-coated endocytic vesicle membrane
0.34	GO:0005765	lysosomal membrane
0.34	GO:0012507	ER to Golgi transport vesicle membrane
0.34	GO:0010008	endosome membrane

sp|P29975|AQP1_RAT
Aquaporin-1
Search

AQP1

0.89	Aquaporin 1, Colton blood group antigen

0.58	GO:0085018	maintenance of symbiont-containing vacuole by host
0.57	GO:0003097	renal water transport
0.56	GO:0072230	metanephric proximal straight tubule development
0.56	GO:0072232	metanephric proximal convoluted tubule segment 2 development
0.56	GO:0072220	metanephric descending thin limb development
0.56	GO:0051458	corticotropin secretion
0.56	GO:0021670	lateral ventricle development
0.55	GO:0072239	metanephric glomerulus vasculature development
0.55	GO:0055085	transmembrane transport
0.54	GO:0044241	lipid digestion

0.69	GO:0022803	passive transmembrane transporter activity
0.56	GO:0005372	water transmembrane transporter activity
0.54	GO:0035379	carbon dioxide transmembrane transporter activity
0.53	GO:0046875	ephrin receptor binding
0.49	GO:0015079	potassium ion transmembrane transporter activity
0.48	GO:0030184	nitric oxide transmembrane transporter activity
0.47	GO:0008519	ammonium transmembrane transporter activity
0.47	GO:0015168	glycerol transmembrane transporter activity
0.39	GO:0042802	identical protein binding

0.55	GO:0020003	symbiont-containing vacuole
0.55	GO:0009925	basal plasma membrane
0.54	GO:0005903	brush border
0.52	GO:0016324	apical plasma membrane
0.52	GO:0005901	caveola
0.51	GO:0070062	extracellular exosome
0.50	GO:0030424	axon
0.44	GO:0042383	sarcolemma
0.44	GO:0031253	cell projection membrane
0.43	GO:0031965	nuclear membrane

sp|P29994|ITPR1_RAT
Inositol 1,4,5-trisphosphate receptor type 1
Search

ITPR1

0.93	'Inositol 1,4,5-trisphosphate receptor type 1'

0.85	GO:0048016	inositol phosphate-mediated signaling
0.76	GO:0070588	calcium ion transmembrane transport
0.56	GO:0050882	voluntary musculoskeletal movement
0.56	GO:0051283	negative regulation of sequestering of calcium ion
0.55	GO:0042045	epithelial fluid transport
0.55	GO:0060402	calcium ion transport into cytosol
0.55	GO:0050849	negative regulation of calcium-mediated signaling
0.54	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.54	GO:0032469	endoplasmic reticulum calcium ion homeostasis
0.52	GO:0001666	response to hypoxia

0.85	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.85	GO:0070679	inositol 1,4,5 trisphosphate binding
0.56	GO:0019855	calcium channel inhibitor activity
0.49	GO:0035091	phosphatidylinositol binding
0.43	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.70	GO:0005783	endoplasmic reticulum
0.57	GO:0031088	platelet dense granule membrane
0.56	GO:0031094	platelet dense tubular network
0.56	GO:0005955	calcineurin complex
0.53	GO:0016528	sarcoplasm
0.52	GO:0014069	postsynaptic density
0.52	GO:0005637	nuclear inner membrane
0.48	GO:0005730	nucleolus
0.48	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.46	GO:0031984	organelle subcompartment

sp|P29995|ITPR2_RAT
Inositol 1,4,5-trisphosphate receptor type 2
Search

ITPR2

0.90	Inositol trisphosphate receptor type 2

0.84	GO:0048016	inositol phosphate-mediated signaling
0.76	GO:0070588	calcium ion transmembrane transport
0.57	GO:0051283	negative regulation of sequestering of calcium ion
0.57	GO:0060402	calcium ion transport into cytosol
0.56	GO:0071361	cellular response to ethanol
0.55	GO:0071320	cellular response to cAMP
0.55	GO:0001666	response to hypoxia
0.40	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.40	GO:0050882	voluntary musculoskeletal movement
0.40	GO:0042045	epithelial fluid transport

0.85	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.84	GO:0070679	inositol 1,4,5 trisphosphate binding
0.56	GO:0097110	scaffold protein binding
0.52	GO:0035091	phosphatidylinositol binding
0.44	GO:0005509	calcium ion binding
0.40	GO:0019855	calcium channel inhibitor activity
0.34	GO:0051287	NAD binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.69	GO:0005783	endoplasmic reticulum
0.57	GO:0016528	sarcoplasm
0.52	GO:0043235	receptor complex
0.51	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.50	GO:0005938	cell cortex
0.50	GO:0098588	bounding membrane of organelle
0.49	GO:0031984	organelle subcompartment
0.45	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.42	GO:0031094	platelet dense tubular network

0.34

EC:1.1.1

GO:0016616

sp|P30009|MARCS_RAT
Myristoylated alanine-rich C-kinase substrate
Search

MARCKS

0.97	Myristoylated alanine-rich protein kinase C substrate a

0.59	GO:0051764	actin crosslink formation
0.56	GO:0051017	actin filament bundle assembly
0.54	GO:0051260	protein homooligomerization
0.49	GO:0010842	retina layer formation
0.49	GO:0014706	striated muscle tissue development
0.48	GO:0007420	brain development
0.47	GO:0060538	skeletal muscle organ development
0.47	GO:0060541	respiratory system development
0.45	GO:0030154	cell differentiation
0.43	GO:0016310	phosphorylation

0.78	GO:0005516	calmodulin binding
0.58	GO:0005080	protein kinase C binding
0.54	GO:0051015	actin filament binding
0.52	GO:0042802	identical protein binding
0.44	GO:0016301	kinase activity
0.40	GO:0001786	phosphatidylserine binding
0.32	GO:0004540	ribonuclease activity
0.32	GO:0003723	RNA binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein

0.60	GO:0042585	germinal vesicle
0.57	GO:0032432	actin filament bundle
0.54	GO:0005813	centrosome
0.53	GO:0005938	cell cortex
0.42	GO:0070062	extracellular exosome
0.42	GO:0044307	dendritic branch
0.41	GO:0005925	focal adhesion
0.41	GO:0032059	bleb
0.41	GO:0001520	outer dense fiber
0.40	GO:0033391	chromatoid body

0.32

GO:0016773

sp|P30082|GLR_RAT
Glucagon receptor
Search

GCGR

0.96	Glucagon receptor a

0.74	GO:0071377	cellular response to glucagon stimulus
0.65	GO:0007166	cell surface receptor signaling pathway
0.65	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0010906	regulation of glucose metabolic process
0.56	GO:0019933	cAMP-mediated signaling
0.54	GO:0032881	regulation of polysaccharide metabolic process
0.52	GO:0043467	regulation of generation of precursor metabolites and energy
0.52	GO:0042593	glucose homeostasis
0.51	GO:0042594	response to starvation
0.40	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.75	GO:0004967	glucagon receptor activity
0.59	GO:0016519	gastric inhibitory peptide receptor activity
0.48	GO:0017046	peptide hormone binding
0.43	GO:0044508	glucagon-like peptide 1 receptor activity
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0003735	structural constituent of ribosome

0.51	GO:0005886	plasma membrane
0.38	GO:0005768	endosome
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

sp|P30083|VIPR1_RAT
Vasoactive intestinal polypeptide receptor 1
Search

VIPR1

0.92	Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0007586	digestion
0.35	GO:0006936	muscle contraction
0.35	GO:0002121	inter-male aggressive behavior
0.35	GO:0008284	positive regulation of cell proliferation
0.35	GO:0098916	anterograde trans-synaptic signaling
0.34	GO:0006955	immune response

0.86	GO:0004999	vasoactive intestinal polypeptide receptor activity
0.33	GO:0005515	protein binding

0.52	GO:0005886	plasma membrane
0.50	GO:0043235	receptor complex
0.30	GO:0044425	membrane part

sp|P30099|C11B2_RAT
Cytochrome P450 11B2, mitochondrial
Search

0.76	Cholesterol side-chain cleavage enzyme, mitochondrial

0.68	GO:0006700	C21-steroid hormone biosynthetic process
0.59	GO:0032341	aldosterone metabolic process
0.59	GO:0006705	mineralocorticoid biosynthetic process
0.58	GO:0008211	glucocorticoid metabolic process
0.54	GO:0008203	cholesterol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0046184	aldehyde biosynthetic process
0.49	GO:1901617	organic hydroxy compound biosynthetic process
0.49	GO:0042181	ketone biosynthetic process
0.49	GO:0002017	regulation of blood volume by renal aldosterone

0.69	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
0.68	GO:0008395	steroid hydroxylase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.36	GO:0061899	11-cis-retinal 3,4-desaturase activity
0.36	GO:0061898	all-trans retinoic acid 3,4-desaturase activity
0.36	GO:0061897	all-trans retinal 3,4-desaturase activity
0.36	GO:0061896	all-trans retinol 3,4-desaturase activity
0.36	GO:0008289	lipid binding
0.36	GO:0043178	alcohol binding

0.55	GO:0005739	mitochondrion
0.48	GO:0031967	organelle envelope
0.48	GO:0031090	organelle membrane
0.36	GO:0036477	somatodendritic compartment
0.35	GO:0043005	neuron projection
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0030176	integral component of endoplasmic reticulum membrane
0.33	GO:0044297	cell body
0.33	GO:0070013	intracellular organelle lumen

0.69

EC:1.14.15

GO:0016713

sp|P30100|C11B3_RAT
Cytochrome P450 11B3, mitochondrial
Search

0.76	Cholesterol side-chain cleavage enzyme, mitochondrial

0.68	GO:0006700	C21-steroid hormone biosynthetic process
0.59	GO:0032341	aldosterone metabolic process
0.59	GO:0006705	mineralocorticoid biosynthetic process
0.58	GO:0008211	glucocorticoid metabolic process
0.54	GO:0008203	cholesterol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0046184	aldehyde biosynthetic process
0.49	GO:1901617	organic hydroxy compound biosynthetic process
0.49	GO:0042181	ketone biosynthetic process
0.49	GO:0002017	regulation of blood volume by renal aldosterone

0.69	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
0.68	GO:0008395	steroid hydroxylase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.36	GO:0061899	11-cis-retinal 3,4-desaturase activity
0.36	GO:0061898	all-trans retinoic acid 3,4-desaturase activity
0.36	GO:0061897	all-trans retinal 3,4-desaturase activity
0.36	GO:0061896	all-trans retinol 3,4-desaturase activity
0.36	GO:0008289	lipid binding
0.36	GO:0043178	alcohol binding

0.55	GO:0005739	mitochondrion
0.48	GO:0031967	organelle envelope
0.48	GO:0031090	organelle membrane
0.36	GO:0036477	somatodendritic compartment
0.35	GO:0043005	neuron projection
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0030176	integral component of endoplasmic reticulum membrane
0.33	GO:0044297	cell body
0.33	GO:0070013	intracellular organelle lumen

0.69

EC:1.14.15

GO:0016713

sp|P30120|TIMP1_RAT
Metalloproteinase inhibitor 1
Search

TIMP1

0.97	Tissue inhibitor of metalloproteinase 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.71	GO:2001044	regulation of integrin-mediated signaling pathway
0.70	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.67	GO:1901164	negative regulation of trophoblast cell migration
0.67	GO:1905049	negative regulation of metallopeptidase activity
0.63	GO:0008284	positive regulation of cell proliferation
0.61	GO:0010469	regulation of receptor activity
0.50	GO:0034097	response to cytokine
0.49	GO:0009725	response to hormone
0.44	GO:0051216	cartilage development

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.64	GO:0005125	cytokine activity
0.53	GO:0002020	protease binding
0.51	GO:0008083	growth factor activity
0.50	GO:0008270	zinc ion binding
0.34	GO:0008237	metallopeptidase activity

0.66	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.37	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0005581	collagen trimer

sp|P30121|TIMP2_RAT
Metalloproteinase inhibitor 2
Search

TIMP2

0.92	Tissue inhibitor of metalloproteinase 2

0.75	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:1905049	negative regulation of metallopeptidase activity
0.48	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.45	GO:0034097	response to cytokine
0.44	GO:0009725	response to hormone
0.42	GO:0032487	regulation of Rap protein signal transduction
0.42	GO:0030814	regulation of cAMP metabolic process
0.41	GO:0051349	positive regulation of lyase activity
0.41	GO:0031281	positive regulation of cyclase activity
0.41	GO:0045664	regulation of neuron differentiation

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.51	GO:0002020	protease binding
0.42	GO:0005178	integrin binding
0.42	GO:0098770	FBXO family protein binding
0.42	GO:0008270	zinc ion binding
0.37	GO:0008047	enzyme activator activity
0.36	GO:0008237	metallopeptidase activity

0.65	GO:0005576	extracellular region
0.40	GO:0030426	growth cone
0.40	GO:0009986	cell surface
0.40	GO:0043025	neuronal cell body
0.37	GO:1904724	tertiary granule lumen
0.37	GO:0035580	specific granule lumen
0.37	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005634	nucleus

sp|P30152|NGAL_RAT
Neutrophil gelatinase-associated lipocalin
Search

LCN2

0.97	Neutrophil gelatinase-associated lipocalin

0.60	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.56	GO:0045087	innate immune response
0.55	GO:0015891	siderophore transport
0.54	GO:0009615	response to virus
0.46	GO:0010046	response to mycotoxin
0.45	GO:0070207	protein homotrimerization
0.44	GO:0071345	cellular response to cytokine stimulus
0.44	GO:0070301	cellular response to hydrogen peroxide
0.44	GO:0070555	response to interleukin-1
0.44	GO:0071222	cellular response to lipopolysaccharide

0.51	GO:0036094	small molecule binding
0.48	GO:0005506	iron ion binding
0.44	GO:0002020	protease binding
0.42	GO:0042803	protein homodimerization activity

0.57	GO:0005615	extracellular space
0.42	GO:1903561	extracellular vesicle
0.40	GO:0035580	specific granule lumen
0.40	GO:0005829	cytosol

sp|P30191|GBRA6_RAT
Gamma-aminobutyric acid receptor subunit alpha-6
Search

GABRA6

0.95	Gamma-aminobutyric acid receptor subunit alpha-6

0.82	GO:0007214	gamma-aminobutyric acid signaling pathway
0.73	GO:0006821	chloride transport
0.59	GO:0034220	ion transmembrane transport
0.50	GO:2001023	regulation of response to drug
0.48	GO:0007417	central nervous system development
0.36	GO:0051932	synaptic transmission, GABAergic
0.36	GO:0051291	protein heterooligomerization

0.83	GO:0004890	GABA-A receptor activity
0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.41	GO:0005254	chloride channel activity
0.40	GO:0008503	benzodiazepine receptor activity
0.36	GO:0099095	ligand-gated anion channel activity
0.35	GO:0022835	transmitter-gated channel activity
0.33	GO:0008144	drug binding

0.55	GO:0005886	plasma membrane
0.52	GO:1902711	GABA-A receptor complex
0.42	GO:0034707	chloride channel complex
0.41	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0098793	presynapse

sp|P30277|CCNB1_RAT
G2/mitotic-specific cyclin-B1
Search

CCNB1

0.77	Cyclin B1 transcript variant 1

0.56	GO:2000775	histone H3-S10 phosphorylation involved in chromosome condensation
0.55	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.55	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.53	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore
0.52	GO:0048146	positive regulation of fibroblast proliferation
0.52	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.52	GO:0007080	mitotic metaphase plate congression
0.52	GO:0001701	in utero embryonic development
0.51	GO:0007052	mitotic spindle organization
0.50	GO:0045931	positive regulation of mitotic cell cycle

0.54	GO:0005113	patched binding
0.52	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.49	GO:0044389	ubiquitin-like protein ligase binding
0.49	GO:0019901	protein kinase binding
0.42	GO:0016301	kinase activity
0.42	GO:0045296	cadherin binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0060089	molecular transducer activity
0.33	GO:0008324	cation transmembrane transporter activity

0.61	GO:0005634	nucleus
0.55	GO:0097125	cyclin B1-CDK1 complex
0.52	GO:0005813	centrosome
0.50	GO:0000940	condensed chromosome outer kinetochore
0.49	GO:0000922	spindle pole
0.48	GO:0005759	mitochondrial matrix
0.48	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.37

GO:0016773

sp|P30337|CHIN_RAT
N-chimaerin
Search

CHN1

0.93	N-chimaerin

0.74	GO:0043547	positive regulation of GTPase activity
0.63	GO:0051056	regulation of small GTPase mediated signal transduction
0.62	GO:0035556	intracellular signal transduction
0.54	GO:0008045	motor neuron axon guidance
0.53	GO:0050770	regulation of axonogenesis
0.42	GO:0021622	oculomotor nerve morphogenesis
0.41	GO:0021603	cranial nerve formation
0.39	GO:0048013	ephrin receptor signaling pathway
0.34	GO:0009967	positive regulation of signal transduction

0.74	GO:0005096	GTPase activator activity
0.53	GO:0046875	ephrin receptor binding
0.53	GO:0046872	metal ion binding
0.44	GO:0001565	phorbol ester receptor activity
0.35	GO:0005070	SH3/SH2 adaptor activity

0.45

GO:0005622

intracellular

sp|P30348|CXCL2_RAT
C-X-C motif chemokine 2
Search

0.88	C-X-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.72	GO:0006952	defense response
0.57	GO:1990266	neutrophil migration
0.55	GO:0042119	neutrophil activation
0.52	GO:0090023	positive regulation of neutrophil chemotaxis
0.51	GO:0002237	response to molecule of bacterial origin
0.50	GO:0070098	chemokine-mediated signaling pathway
0.48	GO:0033993	response to lipid

0.84	GO:0008009	chemokine activity
0.63	GO:0045236	CXCR chemokine receptor binding
0.41	GO:0008083	growth factor activity
0.35	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.33	GO:0008047	enzyme activator activity
0.33	GO:0005355	glucose transmembrane transporter activity
0.33	GO:0016787	hydrolase activity

0.71	GO:0005615	extracellular space
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0034774	secretory granule lumen
0.34	GO:0042581	specific granule
0.34	GO:0031091	platelet alpha granule
0.30	GO:0016020	membrane

0.35	EC:1.5.1.5	GO:0004488
0.35	KEGG:R01220	GO:0004488

sp|P30349|LKHA4_RAT
Leukotriene A-4 hydrolase
Search

LTA4H

0.79	Leukotriene A-4 hydrolase

0.85	GO:0019370	leukotriene biosynthetic process
0.60	GO:0006508	proteolysis
0.56	GO:0043171	peptide catabolic process
0.45	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.44	GO:0030593	neutrophil chemotaxis
0.42	GO:0006954	inflammatory response
0.42	GO:0044267	cellular protein metabolic process
0.42	GO:0044255	cellular lipid metabolic process
0.36	GO:0060509	Type I pneumocyte differentiation
0.35	GO:0043312	neutrophil degranulation

0.80	GO:0004463	leukotriene-A4 hydrolase activity
0.67	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.61	GO:0004301	epoxide hydrolase activity
0.53	GO:0004177	aminopeptidase activity
0.47	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen

0.80	EC:3.3.2.6	GO:0004463
0.80	KEGG:R03057	GO:0004463

sp|P30427|PLEC_RAT
Plectin
Search

0.71

Plectin b

0.48	GO:0031581	hemidesmosome assembly
0.37	GO:0007519	skeletal muscle tissue development
0.37	GO:0007626	locomotory behavior
0.33	GO:0007565	female pregnancy
0.33	GO:0007584	response to nutrient
0.33	GO:0030855	epithelial cell differentiation
0.32	GO:0007010	cytoskeleton organization

0.73	GO:0003779	actin binding
0.48	GO:0030506	ankyrin binding
0.46	GO:0045296	cadherin binding
0.36	GO:0008017	microtubule binding
0.35	GO:0008307	structural constituent of muscle
0.35	GO:0005509	calcium ion binding
0.33	GO:0047485	protein N-terminus binding
0.33	GO:0005200	structural constituent of cytoskeleton
0.32	GO:0003723	RNA binding

0.69	GO:0005856	cytoskeleton
0.49	GO:0005903	brush border
0.49	GO:0030056	hemidesmosome
0.48	GO:0043292	contractile fiber
0.47	GO:0042383	sarcolemma
0.46	GO:0005925	focal adhesion
0.42	GO:0005829	cytosol
0.34	GO:0031012	extracellular matrix
0.34	GO:0016528	sarcoplasm
0.34	GO:0070062	extracellular exosome

sp|P30543|AA2AR_RAT
Adenosine receptor A2a
Search

ADORA2A

0.95	Adenosine receptor A2

0.85	GO:0001973	adenosine receptor signaling pathway
0.58	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.58	GO:0060080	inhibitory postsynaptic potential
0.57	GO:0001963	synaptic transmission, dopaminergic
0.57	GO:0001975	response to amphetamine
0.57	GO:0042755	eating behavior
0.57	GO:0046636	negative regulation of alpha-beta T cell activation
0.57	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.55	GO:0050728	negative regulation of inflammatory response
0.55	GO:2001235	positive regulation of apoptotic signaling pathway

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.50	GO:0042802	identical protein binding
0.49	GO:0019899	enzyme binding
0.42	GO:0031802	type 5 metabotropic glutamate receptor binding
0.41	GO:0051393	alpha-actinin binding
0.39	GO:0046982	protein heterodimerization activity
0.34	GO:0016519	gastric inhibitory peptide receptor activity

0.55	GO:0005886	plasma membrane
0.52	GO:0098794	postsynapse
0.41	GO:0044304	main axon
0.40	GO:0032279	asymmetric synapse
0.40	GO:0048786	presynaptic active zone
0.40	GO:0043025	neuronal cell body
0.40	GO:0030425	dendrite
0.40	GO:0031252	cell leading edge
0.39	GO:0005882	intermediate filament
0.37	GO:0012505	endomembrane system

sp|P30551|CCKAR_RAT
Cholecystokinin receptor type A
Search

CCKAR

0.96	Cholecystokinin receptor type A

0.79	GO:0038188	cholecystokinin signaling pathway
0.57	GO:0001764	neuron migration
0.55	GO:0030900	forebrain development
0.55	GO:0007409	axonogenesis
0.47	GO:0007631	feeding behavior
0.47	GO:0007586	digestion
0.47	GO:0046883	regulation of hormone secretion
0.46	GO:1901652	response to peptide
0.44	GO:0032870	cellular response to hormone stimulus
0.37	GO:0007584	response to nutrient

0.79	GO:0004951	cholecystokinin receptor activity
0.69	GO:0015054	gastrin receptor activity
0.45	GO:0042277	peptide binding

0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0043195	terminal bouton
0.35	GO:0005764	lysosome
0.35	GO:0005768	endosome
0.34	GO:0005783	endoplasmic reticulum

sp|P30553|GASR_RAT
Gastrin/cholecystokinin type B receptor
Search

CCKBR

0.90	Cholecystokinin receptor type A

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0001696	gastric acid secretion
0.55	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0048565	digestive tract development
0.52	GO:0048732	gland development
0.37	GO:0007610	behavior
0.37	GO:0090274	positive regulation of somatostatin secretion
0.37	GO:0001821	histamine secretion
0.37	GO:0044849	estrous cycle

0.85	GO:0015054	gastrin receptor activity
0.60	GO:0031741	type B gastrin/cholecystokinin receptor binding
0.54	GO:0004951	cholecystokinin receptor activity
0.36	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0042277	peptide binding
0.32	GO:0005216	ion channel activity

0.37	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P30560|V1AR_RAT
Vasopressin V1a receptor
Search

AVPR1A

0.96	Vasotocin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0001992	regulation of systemic arterial blood pressure by vasopressin
0.48	GO:0045907	positive regulation of vasoconstriction
0.47	GO:0042711	maternal behavior
0.45	GO:1901652	response to peptide
0.44	GO:0009725	response to hormone
0.43	GO:0071495	cellular response to endogenous stimulus
0.43	GO:0071310	cellular response to organic substance
0.42	GO:0043084	penile erection
0.42	GO:0002125	maternal aggressive behavior

0.85	GO:0005000	vasopressin receptor activity
0.45	GO:0042277	peptide binding
0.43	GO:0031894	V1A vasopressin receptor binding
0.40	GO:0042562	hormone binding
0.35	GO:0005080	protein kinase C binding

0.50	GO:0005886	plasma membrane
0.38	GO:0031410	cytoplasmic vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0043204	perikaryon
0.34	GO:0043005	neuron projection
0.33	GO:0012505	endomembrane system
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P30680|SSR2_RAT
Somatostatin receptor type 2
Search

SSTR2

0.97	Somatostatin receptor type 2

0.85	GO:0038169	somatostatin receptor signaling pathway
0.76	GO:0009755	hormone-mediated signaling pathway
0.56	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.53	GO:0007218	neuropeptide signaling pathway
0.51	GO:0071385	cellular response to glucocorticoid stimulus
0.50	GO:0071392	cellular response to estradiol stimulus
0.48	GO:0008285	negative regulation of cell proliferation
0.40	GO:0030432	peristalsis
0.39	GO:0021549	cerebellum development
0.38	GO:0006937	regulation of muscle contraction

0.85	GO:0004994	somatostatin receptor activity
0.56	GO:0030165	PDZ domain binding
0.51	GO:0042923	neuropeptide binding
0.35	GO:0017046	peptide hormone binding
0.34	GO:0046982	protein heterodimerization activity

0.48	GO:0005829	cytosol
0.47	GO:0043005	neuron projection
0.43	GO:0005887	integral component of plasma membrane
0.35	GO:0098802	plasma membrane receptor complex

sp|P30710|GPX5_RAT
Epididymal secretory glutathione peroxidase
Search

0.47	Epididymal secretory glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0051289	protein homotetramerization
0.45	GO:0033554	cellular response to stress
0.44	GO:0042744	hydrogen peroxide catabolic process
0.35	GO:0010269	response to selenium ion
0.35	GO:0051412	response to corticosterone
0.35	GO:0002238	response to molecule of fungal origin
0.34	GO:0006749	glutathione metabolic process

0.79	GO:0004602	glutathione peroxidase activity
0.51	GO:0008430	selenium binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.33	GO:0004556	alpha-amylase activity
0.32	GO:0042802	identical protein binding
0.32	GO:0043169	cation binding

0.57	GO:0097524	sperm plasma membrane
0.55	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.32	GO:0005654	nucleoplasm
0.32	GO:0005739	mitochondrion
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.79

EC:1.11.1.9

GO:0004602

sp|P30713|GSTT2_RAT
Glutathione S-transferase theta-2
Search

0.81	Glutathione S-transferase theta-2

0.54	GO:0006749	glutathione metabolic process
0.47	GO:1990823	response to leukemia inhibitory factor
0.45	GO:0071345	cellular response to cytokine stimulus
0.39	GO:1901685	glutathione derivative metabolic process
0.37	GO:0009751	response to salicylic acid
0.36	GO:0098869	cellular oxidant detoxification
0.36	GO:0006336	DNA replication-independent nucleosome assembly
0.35	GO:0044272	sulfur compound biosynthetic process
0.34	GO:0006338	chromatin remodeling
0.34	GO:1901566	organonitrogen compound biosynthetic process

0.57	GO:0004364	glutathione transferase activity
0.38	GO:0004602	glutathione peroxidase activity
0.33	GO:0005515	protein binding

0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.41	GO:0070062	extracellular exosome
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome

0.57

EC:2.5.1.18

GO:0004364

sp|P30729|DRD4_RAT
D(4) dopamine receptor
Search

DRD4

0.88	D(4) dopamine receptor isoform A

0.85	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway
0.58	GO:0032417	positive regulation of sodium:proton antiporter activity
0.57	GO:0034776	response to histamine
0.56	GO:0060080	inhibitory postsynaptic potential
0.56	GO:0042053	regulation of dopamine metabolic process
0.56	GO:0048148	behavioral response to cocaine
0.56	GO:0001975	response to amphetamine
0.55	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.55	GO:0042596	fear response
0.53	GO:0008344	adult locomotory behavior

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.57	GO:0051380	norepinephrine binding
0.57	GO:0051379	epinephrine binding
0.56	GO:0035240	dopamine binding
0.52	GO:0017124	SH3 domain binding
0.49	GO:0042802	identical protein binding
0.36	GO:0015459	potassium channel regulator activity
0.35	GO:0046872	metal ion binding

0.66	GO:0005887	integral component of plasma membrane
0.51	GO:0098794	postsynapse
0.38	GO:0043195	terminal bouton
0.37	GO:0044309	neuron spine
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.36	GO:0012506	vesicle membrane
0.36	GO:0005938	cell cortex

sp|P30823|CTR1_RAT
High affinity cationic amino acid transporter 1
Search

SLC7A1

0.65	High affinity cationic amino acid transporter

0.69	GO:0006865	amino acid transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0006812	cation transport
0.35	GO:0002537	nitric oxide production involved in inflammatory response
0.35	GO:0032006	regulation of TOR signaling
0.34	GO:0043030	regulation of macrophage activation
0.34	GO:0042116	macrophage activation
0.34	GO:0006809	nitric oxide biosynthetic process
0.34	GO:0050727	regulation of inflammatory response
0.33	GO:0098657	import into cell

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0005515	protein binding

0.34	GO:0005886	plasma membrane
0.33	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|P30835|PFKAL_RAT
ATP-dependent 6-phosphofructokinase, liver type
Search

PFKL

0.45	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.57	GO:0046676	negative regulation of insulin secretion
0.56	GO:0009749	response to glucose
0.56	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.50	GO:0051259	protein oligomerization
0.36	GO:1990830	cellular response to leukemia inhibitory factor
0.36	GO:0061718	glucose catabolic process to pyruvate
0.36	GO:0006735	NADH regeneration
0.36	GO:0043312	neutrophil degranulation

0.79	GO:0003872	6-phosphofructokinase activity
0.61	GO:0070095	fructose-6-phosphate binding
0.60	GO:0070061	fructose binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0019900	kinase binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042802	identical protein binding
0.50	GO:0046872	metal ion binding
0.36	GO:0045296	cadherin binding

0.59	GO:0005945	6-phosphofructokinase complex
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.7.1.11

GO:0003872

sp|P30836|LYAM1_RAT
L-selectin
Search

SELL

0.93	L-selectin

0.72	GO:0007155	cell adhesion
0.71	GO:0050900	leukocyte migration
0.53	GO:0033198	response to ATP
0.50	GO:0010572	positive regulation of platelet activation
0.50	GO:0033623	regulation of integrin activation
0.49	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.48	GO:0002687	positive regulation of leukocyte migration
0.48	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.46	GO:0006954	inflammatory response
0.40	GO:0007202	activation of phospholipase C activity

0.64	GO:0070492	oligosaccharide binding
0.57	GO:0005509	calcium ion binding
0.54	GO:0002020	protease binding
0.53	GO:0033691	sialic acid binding
0.51	GO:0050839	cell adhesion molecule binding
0.49	GO:0042806	fucose binding
0.48	GO:0048306	calcium-dependent protein binding
0.48	GO:0008201	heparin binding
0.47	GO:0001530	lipopolysaccharide binding
0.40	GO:0043274	phospholipase binding

0.57	GO:0009897	external side of plasma membrane
0.52	GO:0005887	integral component of plasma membrane
0.50	GO:0031092	platelet alpha granule membrane
0.46	GO:0005615	extracellular space
0.39	GO:0005901	caveola
0.39	GO:0005905	clathrin-coated pit
0.38	GO:0030863	cortical cytoskeleton
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0031088	platelet dense granule membrane

0.33

EC:3.1.4

GO:0008081

sp|P30839|AL3A2_RAT
Fatty aldehyde dehydrogenase
Search

ALDH3A2

0.43	Fatty aldehyde dehydrogenase

0.67	GO:0006081	cellular aldehyde metabolic process
0.57	GO:0033306	phytol metabolic process
0.53	GO:0007422	peripheral nervous system development
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0008544	epidermis development
0.50	GO:0007417	central nervous system development
0.39	GO:0006714	sesquiterpenoid metabolic process
0.35	GO:0030148	sphingolipid biosynthetic process
0.34	GO:0000302	response to reactive oxygen species
0.34	GO:0009062	fatty acid catabolic process

0.77	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.54	GO:0046577	long-chain-alcohol oxidase activity
0.54	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.41	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.39	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity

0.47	GO:0005783	endoplasmic reticulum
0.42	GO:0031090	organelle membrane
0.41	GO:0005740	mitochondrial envelope
0.38	GO:0005829	cytosol
0.38	GO:0042579	microbody
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0098805	whole membrane
0.35	GO:0005886	plasma membrane

0.77

EC:1.2.1.5

GO:0004030

sp|P30904|MIF_RAT
Macrophage migration inhibitory factor
Search

MIF

0.85	Macrophage migration inhibitory factor

0.79	GO:0010760	negative regulation of macrophage chemotaxis
0.78	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.78	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.77	GO:0010739	positive regulation of protein kinase A signaling
0.76	GO:0090344	negative regulation of cell aging
0.76	GO:0070207	protein homotrimerization
0.76	GO:0048146	positive regulation of fibroblast proliferation
0.75	GO:0071157	negative regulation of cell cycle arrest
0.75	GO:0046457	prostanoid biosynthetic process
0.75	GO:0030890	positive regulation of B cell proliferation

0.85	GO:0050178	phenylpyruvate tautomerase activity
0.84	GO:0004167	dopachrome isomerase activity
0.76	GO:0042056	chemoattractant activity
0.74	GO:0005125	cytokine activity
0.68	GO:0005126	cytokine receptor binding
0.66	GO:0002020	protease binding
0.64	GO:0042802	identical protein binding
0.49	GO:0042289	MHC class II protein binding
0.38	GO:0032403	protein complex binding
0.33	GO:0003676	nucleic acid binding

0.68	GO:0005615	extracellular space
0.66	GO:0009986	cell surface
0.65	GO:0043209	myelin sheath
0.61	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.42	GO:1903561	extracellular vesicle
0.40	GO:1904813	ficolin-1-rich granule lumen
0.39	GO:0034774	secretory granule lumen

0.85	EC:5.3.2.1	GO:0050178
0.84	KEGG:R03673	GO:0004167

sp|P30919|ASPG_RAT
N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase
Search

AGA

0.75	Aspartylglucosaminidase

0.59	GO:0006517	protein deglycosylation
0.49	GO:0051604	protein maturation
0.36	GO:0006508	proteolysis
0.35	GO:0043312	neutrophil degranulation

0.62	GO:0003948	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity
0.40	GO:0043621	protein self-association
0.36	GO:0008233	peptidase activity

0.55	GO:0005764	lysosome
0.51	GO:0005615	extracellular space
0.50	GO:0005783	endoplasmic reticulum
0.37	GO:1903561	extracellular vesicle
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.62	EC:3.5.1.26	GO:0003948
0.62	KEGG:R03421	GO:0003948

sp|P30936|SSR3_RAT
Somatostatin receptor type 3
Search

SSTR3

0.95	Type-three somatostatin receptor subtype B

0.86	GO:0038169	somatostatin receptor signaling pathway
0.77	GO:0009755	hormone-mediated signaling pathway
0.49	GO:0032467	positive regulation of cytokinesis
0.49	GO:0090276	regulation of peptide hormone secretion
0.49	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.48	GO:0007268	chemical synaptic transmission
0.47	GO:0042593	glucose homeostasis
0.47	GO:0050708	regulation of protein secretion
0.46	GO:0007218	neuropeptide signaling pathway
0.45	GO:0071385	cellular response to glucocorticoid stimulus

0.86	GO:0004994	somatostatin receptor activity
0.52	GO:0042923	neuropeptide binding
0.50	GO:0005102	receptor binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0060170	ciliary membrane
0.55	GO:0097730	non-motile cilium
0.48	GO:0043005	neuron projection
0.44	GO:0005887	integral component of plasma membrane
0.36	GO:0005581	collagen trimer
0.34	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm

sp|P30937|SSR4_RAT
Somatostatin receptor type 4
Search

SSTR4

0.96	Somatostatin receptor subtype 1

0.86	GO:0038169	somatostatin receptor signaling pathway
0.77	GO:0009755	hormone-mediated signaling pathway
0.51	GO:1990830	cellular response to leukemia inhibitory factor
0.49	GO:0007218	neuropeptide signaling pathway
0.49	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.48	GO:0071396	cellular response to lipid
0.48	GO:0071407	cellular response to organic cyclic compound
0.48	GO:0008285	negative regulation of cell proliferation
0.48	GO:0007215	glutamate receptor signaling pathway
0.46	GO:0051384	response to glucocorticoid

0.86	GO:0004994	somatostatin receptor activity
0.52	GO:0042923	neuropeptide binding
0.36	GO:0005515	protein binding
0.36	GO:0017046	peptide hormone binding

0.47	GO:0043005	neuron projection
0.44	GO:0005887	integral component of plasma membrane
0.35	GO:0098802	plasma membrane receptor complex
0.35	GO:0005737	cytoplasm

sp|P30938|SSR5_RAT
Somatostatin receptor type 5
Search

SSTR5

0.97	Somatostatin receptor subtype 5

0.86	GO:0038170	somatostatin signaling pathway
0.54	GO:0032467	positive regulation of cytokinesis
0.54	GO:0090276	regulation of peptide hormone secretion
0.52	GO:0050708	regulation of protein secretion
0.52	GO:0042593	glucose homeostasis
0.49	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.48	GO:0071385	cellular response to glucocorticoid stimulus
0.48	GO:0007268	chemical synaptic transmission
0.45	GO:0008285	negative regulation of cell proliferation
0.42	GO:0007218	neuropeptide signaling pathway

0.86	GO:0004994	somatostatin receptor activity
0.52	GO:0042923	neuropeptide binding
0.44	GO:0005102	receptor binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0120025	plasma membrane bounded cell projection
0.47	GO:0097458	neuron part
0.46	GO:0098590	plasma membrane region
0.44	GO:0098588	bounding membrane of organelle
0.44	GO:0005887	integral component of plasma membrane
0.44	GO:0044463	cell projection part
0.34	GO:0005581	collagen trimer
0.33	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region

sp|P30940|5HT1F_RAT
5-hydroxytryptamine receptor 1F
Search

HTR1F

0.97	5-hydroxytryptamine (Serotonin) receptor 1F

0.85	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.74	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.37	GO:0098916	anterograde trans-synaptic signaling

0.85	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.76	GO:0051378	serotonin binding

0.67

GO:0005887

integral component of plasma membrane

sp|P30951|GPR12_RAT
G-protein coupled receptor 12
Search

GPR12

0.66	G-protein coupled receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0006874	cellular calcium ion homeostasis
0.43	GO:0090520	sphingolipid mediated signaling pathway
0.36	GO:0040020	regulation of meiotic nuclear division

0.71	GO:0004930	G-protein coupled receptor activity
0.57	GO:0031210	phosphatidylcholine binding

0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P30969|GNRHR_RAT
Gonadotropin-releasing hormone receptor
Search

GNRHR

0.86	Pituitary gonadotropin releasing hormone receptor

0.76	GO:0097211	cellular response to gonadotropin-releasing hormone
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0021764	amygdala development
0.36	GO:0060996	dendritic spine development
0.35	GO:0021766	hippocampus development
0.35	GO:0007623	circadian rhythm
0.35	GO:0007612	learning
0.35	GO:0006508	proteolysis
0.35	GO:0008285	negative regulation of cell proliferation
0.35	GO:0007626	locomotory behavior

0.84	GO:0016500	protein-hormone receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.47	GO:0042277	peptide binding
0.39	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.38	GO:0001653	peptide receptor activity
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005515	protein binding

0.43	GO:0005887	integral component of plasma membrane
0.32	GO:0005737	cytoplasm

0.35

GO:0004252

sp|P30994|5HT2B_RAT
5-hydroxytryptamine receptor 2B
Search

HTR2B

0.97	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

0.85	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.85	GO:0006939	smooth muscle contraction
0.83	GO:0050795	regulation of behavior
0.80	GO:0042310	vasoconstriction
0.75	GO:0007507	heart development
0.64	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.62	GO:0007202	activation of phospholipase C activity
0.62	GO:0071502	cellular response to temperature stimulus
0.62	GO:0070528	protein kinase C signaling
0.61	GO:0051000	positive regulation of nitric-oxide synthase activity

0.85	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.63	GO:0051378	serotonin binding
0.60	GO:0001965	G-protein alpha-subunit binding
0.53	GO:0005096	GTPase activator activity
0.43	GO:0008144	drug binding

0.65	GO:0005887	integral component of plasma membrane
0.53	GO:0043198	dendritic shaft
0.50	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm
0.38	GO:0045202	synapse
0.38	GO:0030054	cell junction
0.35	GO:0043025	neuronal cell body

sp|P31000|VIME_RAT
Vimentin
Search

VIM

0.85	Putative nuclear envelope protein lamin intermediate filament superfamily

0.59	GO:0060020	Bergmann glial cell differentiation
0.58	GO:0070307	lens fiber cell development
0.58	GO:0010714	positive regulation of collagen metabolic process
0.58	GO:0032965	regulation of collagen biosynthetic process
0.58	GO:0014002	astrocyte development
0.58	GO:0045109	intermediate filament organization
0.56	GO:0060395	SMAD protein signal transduction
0.56	GO:0071346	cellular response to interferon-gamma
0.56	GO:0010977	negative regulation of neuron projection development
0.56	GO:0043488	regulation of mRNA stability

0.62	GO:0005198	structural molecule activity
0.60	GO:1990254	keratin filament binding
0.57	GO:0097110	scaffold protein binding
0.55	GO:0008022	protein C-terminus binding
0.52	GO:0019904	protein domain specific binding
0.52	GO:0003725	double-stranded RNA binding
0.51	GO:0042802	identical protein binding
0.35	GO:0051721	protein phosphatase 2A binding
0.34	GO:0019901	protein kinase binding

0.79	GO:0005882	intermediate filament
0.55	GO:0045335	phagocytic vesicle
0.55	GO:0005844	polysome
0.54	GO:0031252	cell leading edge
0.52	GO:0043005	neuron projection
0.52	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

sp|P31016|DLG4_RAT
Disks large homolog 4
Search

DLG4

0.89	Disks large like protein 4

0.79	GO:2000821	regulation of grooming behavior
0.77	GO:0035641	locomotory exploration behavior
0.76	GO:0071625	vocalization behavior
0.76	GO:0060997	dendritic spine morphogenesis
0.76	GO:0016188	synaptic vesicle maturation
0.76	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.76	GO:0035418	protein localization to synapse
0.75	GO:0097120	receptor localization to synapse
0.74	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.74	GO:0035176	social behavior

0.84	GO:0035255	ionotropic glutamate receptor binding
0.75	GO:0031811	G-protein coupled nucleotide receptor binding
0.74	GO:0097110	scaffold protein binding
0.71	GO:0008022	protein C-terminus binding
0.71	GO:0031697	beta-1 adrenergic receptor binding
0.71	GO:0097109	neuroligin family protein binding
0.70	GO:0031748	D1 dopamine receptor binding
0.68	GO:0004385	guanylate kinase activity
0.67	GO:0033130	acetylcholine receptor binding
0.67	GO:0019900	kinase binding

0.81	GO:0008328	ionotropic glutamate receptor complex
0.78	GO:0014069	postsynaptic density
0.78	GO:0044300	cerebellar mossy fiber
0.77	GO:0044224	juxtaparanode region of axon
0.77	GO:0099634	postsynaptic specialization membrane
0.75	GO:0060076	excitatory synapse
0.73	GO:0043197	dendritic spine
0.72	GO:0044306	neuron projection terminus
0.71	GO:0016323	basolateral plasma membrane
0.70	GO:0008021	synaptic vesicle

0.68

EC:2.7.4.8

GO:0004385

sp|P31042|CD28_RAT
T-cell-specific surface glycoprotein CD28
Search

CD28

0.96	T-cell-specific surface glycoprotein CD28

0.73	GO:0006955	immune response
0.67	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.64	GO:0042102	positive regulation of T cell proliferation
0.63	GO:0045840	positive regulation of mitotic nuclear division
0.61	GO:0045066	regulatory T cell differentiation
0.61	GO:0032753	positive regulation of interleukin-4 production
0.61	GO:0032733	positive regulation of interleukin-10 production
0.60	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.60	GO:0002863	positive regulation of inflammatory response to antigenic stimulus
0.60	GO:0045060	negative thymic T cell selection

0.58	GO:0005070	SH3/SH2 adaptor activity
0.57	GO:0002020	protease binding
0.54	GO:0019901	protein kinase binding
0.39	GO:0015026	coreceptor activity
0.37	GO:0042802	identical protein binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0046983	protein dimerization activity

0.58	GO:0001772	immunological synapse
0.56	GO:0009897	external side of plasma membrane
0.56	GO:0098636	protein complex involved in cell adhesion
0.40	GO:0044214	spanning component of plasma membrane
0.36	GO:0045121	membrane raft
0.34	GO:0005829	cytosol

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P31044|PEBP1_RAT
Phosphatidylethanolamine-binding protein 1
Search

PEBP1

0.64	Phosphatidylethanolamine-binding protein 1

0.55	GO:0010951	negative regulation of endopeptidase activity
0.53	GO:0060409	positive regulation of acetylcholine metabolic process
0.53	GO:0048240	sperm capacitation
0.51	GO:0051412	response to corticosterone
0.50	GO:0043950	positive regulation of cAMP-mediated signaling
0.50	GO:0051602	response to electrical stimulus
0.50	GO:0010243	response to organonitrogen compound
0.49	GO:0042755	eating behavior
0.49	GO:0002026	regulation of the force of heart contraction
0.49	GO:0014823	response to activity

0.70	GO:0019901	protein kinase binding
0.56	GO:0004867	serine-type endopeptidase inhibitor activity
0.53	GO:0008289	lipid binding
0.44	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0005102	receptor binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019210	kinase inhibitor activity
0.38	GO:0003723	RNA binding

0.50	GO:0043209	myelin sheath
0.48	GO:0043679	axon terminus
0.48	GO:0009986	cell surface
0.47	GO:0005791	rough endoplasmic reticulum
0.47	GO:0008021	synaptic vesicle
0.47	GO:0043025	neuronal cell body
0.47	GO:0045177	apical part of cell
0.46	GO:0005615	extracellular space
0.46	GO:0005741	mitochondrial outer membrane
0.44	GO:0005794	Golgi apparatus

sp|P31053|CD37_RAT
Leukocyte antigen CD37
Search

CD37

0.61	Tetraspanin

0.44

GO:0007166

cell surface receptor signaling pathway

0.62	GO:0001772	immunological synapse
0.42	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus

sp|P31210|AK1D1_RAT
3-oxo-5-beta-steroid 4-dehydrogenase
Search

AKR1D1

0.96	3-oxo-5-beta-steroid 4-dehydrogenase

0.58	GO:0006707	cholesterol catabolic process
0.58	GO:0006699	bile acid biosynthetic process
0.58	GO:0008209	androgen metabolic process
0.58	GO:0008207	C21-steroid hormone metabolic process
0.56	GO:0007586	digestion
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0030573	bile acid catabolic process
0.34	GO:0008284	positive regulation of cell proliferation
0.34	GO:0042446	hormone biosynthetic process
0.34	GO:0006836	neurotransmitter transport

0.54	GO:0016491	oxidoreductase activity
0.36	GO:0005212	structural constituent of eye lens
0.35	GO:0005496	steroid binding
0.34	GO:0005328	neurotransmitter:sodium symporter activity

0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.54

GO:0016491

sp|P31211|CBG_RAT
Corticosteroid-binding globulin
Search

SERPINA6

0.84	corticosteroid-binding globulin precursor

0.55	GO:0008211	glucocorticoid metabolic process
0.52	GO:0010951	negative regulation of endopeptidase activity
0.42	GO:0070327	thyroid hormone transport
0.39	GO:0006953	acute-phase response
0.36	GO:0043434	response to peptide hormone
0.36	GO:0034097	response to cytokine
0.35	GO:0034516	response to vitamin B6
0.34	GO:0002576	platelet degranulation
0.34	GO:0006955	immune response
0.34	GO:0030277	maintenance of gastrointestinal epithelium

0.54	GO:0005496	steroid binding
0.53	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0002020	protease binding
0.37	GO:0042802	identical protein binding
0.34	GO:0008233	peptidase activity
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0031093	platelet alpha granule lumen
0.35	GO:0035578	azurophil granule lumen
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0008233

sp|P31214|S5A2_RAT
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Search

SRD5A2

0.97	Steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

0.68	GO:0008202	steroid metabolic process
0.57	GO:0046661	male sex differentiation
0.56	GO:0008406	gonad development
0.56	GO:0048806	genitalia development
0.55	GO:0042446	hormone biosynthetic process
0.55	GO:0034754	cellular hormone metabolic process
0.52	GO:0055114	oxidation-reduction process
0.52	GO:1901617	organic hydroxy compound biosynthetic process
0.51	GO:0042181	ketone biosynthetic process
0.49	GO:0008610	lipid biosynthetic process

0.77	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity
0.62	GO:0009917	sterol 5-alpha reductase activity
0.62	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.45	GO:0047751	cholestenone 5-alpha-reductase activity
0.37	GO:0033218	amide binding

0.49	GO:0005737	cytoplasm
0.41	GO:0070852	cell body fiber
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0043025	neuronal cell body
0.38	GO:0031984	organelle subcompartment
0.37	GO:0031090	organelle membrane
0.36	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.77	EC:1.3.99.5	GO:0003865
0.45	KEGG:R02610	GO:0047751

sp|P31232|TAGL_RAT
Transgelin
Search

TAGLN

0.80	Transgelin

0.50	GO:0030855	epithelial cell differentiation
0.43	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0007010	cytoskeleton organization
0.39	GO:0000902	cell morphogenesis
0.38	GO:0030029	actin filament-based process
0.36	GO:0033227	dsRNA transport
0.34	GO:0048731	system development
0.34	GO:0061061	muscle structure development

0.77	GO:0051015	actin filament binding
0.36	GO:0051032	nucleic acid transmembrane transporter activity
0.34	GO:0030674	protein binding, bridging

0.44	GO:0043209	myelin sheath
0.39	GO:0005634	nucleus
0.38	GO:0015629	actin cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P31246|HXA2_RAT
Homeobox protein Hox-A2
Search

HOXA2

0.79	Homeobox protein Hox-A2

0.67	GO:0007275	multicellular organism development
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.38	GO:0002076	osteoblast development
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0071300	cellular response to retinoic acid
0.37	GO:0045668	negative regulation of osteoblast differentiation
0.37	GO:0001709	cell fate determination
0.37	GO:1904888	cranial skeletal system development

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P31325|PHKG2_RAT
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
Search

PHKG2

0.55	Phosphorylase kinase catalytic subunit gamma 2

0.76	GO:0005978	glycogen biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.51	GO:0018210	peptidyl-threonine modification
0.50	GO:0018209	peptidyl-serine modification
0.43	GO:0035556	intracellular signal transduction
0.36	GO:0001525	angiogenesis
0.36	GO:0005980	glycogen catabolic process
0.35	GO:0045819	positive regulation of glycogen catabolic process

0.85	GO:0004689	phosphorylase kinase activity
0.78	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0050321	tau-protein kinase activity
0.38	GO:0019899	enzyme binding
0.32	GO:0003677	DNA binding

0.85	GO:0005964	phosphorylase kinase complex
0.48	GO:0005829	cytosol
0.35	GO:0098723	skeletal muscle myofibril
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.7.11.19

GO:0004689

sp|P31388|5HT6R_RAT
5-hydroxytryptamine receptor 6
Search

HTR6

0.92	5-hydroxytryptamine receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0007210	serotonin receptor signaling pathway
0.57	GO:0021795	cerebral cortex cell migration
0.54	GO:0032008	positive regulation of TOR signaling
0.43	GO:0019933	cAMP-mediated signaling
0.41	GO:0045823	positive regulation of heart contraction
0.39	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.38	GO:0001659	temperature homeostasis
0.38	GO:0014058	negative regulation of acetylcholine secretion, neurotransmission
0.38	GO:0014053	negative regulation of gamma-aminobutyric acid secretion

0.72	GO:0004930	G-protein coupled receptor activity
0.70	GO:0099589	serotonin receptor activity
0.63	GO:0030594	neurotransmitter receptor activity
0.39	GO:0051380	norepinephrine binding
0.38	GO:0031699	beta-3 adrenergic receptor binding
0.37	GO:0051379	epinephrine binding
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0032795	heterotrimeric G-protein binding
0.34	GO:0001653	peptide receptor activity
0.33	GO:0008373	sialyltransferase activity

0.52	GO:0005929	cilium
0.38	GO:0005886	plasma membrane
0.36	GO:0030425	dendrite
0.36	GO:0043235	receptor complex
0.34	GO:0061617	MICOS complex
0.32	GO:0005840	ribosome

0.33

EC:2.4.99

GO:0008373

sp|P31390|HRH1_RAT
Histamine H1 receptor
Search

HRH1

0.97	Histamine H1 receptor

0.85	GO:0048245	eosinophil chemotaxis
0.85	GO:0043114	regulation of vascular permeability
0.85	GO:0045907	positive regulation of vasoconstriction
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0008542	visual learning
0.61	GO:0050804	modulation of chemical synaptic transmission
0.60	GO:0007613	memory
0.49	GO:0071420	cellular response to histamine
0.49	GO:0006954	inflammatory response
0.39	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process

0.85	GO:0004969	histamine receptor activity
0.38	GO:0051381	histamine binding
0.37	GO:0015085	calcium ion transmembrane transporter activity
0.35	GO:0016907	G-protein coupled acetylcholine receptor activity

0.52	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P31392|GP182_RAT
G-protein coupled receptor 182
Search

GPR182

0.59	G-protein coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0001570	vasculogenesis
0.55	GO:0001525	angiogenesis
0.50	GO:0006935	chemotaxis
0.43	GO:0071310	cellular response to organic substance
0.42	GO:0035556	intracellular signal transduction
0.42	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.42	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.42	GO:0031623	receptor internalization
0.41	GO:0034097	response to cytokine

0.72	GO:0004930	G-protein coupled receptor activity
0.57	GO:0019956	chemokine binding
0.57	GO:0015026	coreceptor activity
0.45	GO:0001653	peptide receptor activity
0.41	GO:0004896	cytokine receptor activity
0.41	GO:0005044	scavenger receptor activity
0.36	GO:0030284	estrogen receptor activity
0.35	GO:1990239	steroid hormone binding
0.34	GO:0003682	chromatin binding
0.33	GO:0035091	phosphatidylinositol binding

0.41	GO:0005905	clathrin-coated pit
0.40	GO:0005768	endosome
0.39	GO:0009986	cell surface
0.38	GO:0005886	plasma membrane
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0045095	keratin filament
0.34	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0031984	organelle subcompartment
0.33	GO:0031967	organelle envelope

sp|P31394|PROC_RAT
Vitamin K-dependent protein C
Search

PROC

0.91	Vitamin K-dependent protein C

0.76	GO:0007596	blood coagulation
0.60	GO:0006508	proteolysis
0.60	GO:1901552	positive regulation of endothelial cell development
0.59	GO:1903140	regulation of establishment of endothelial barrier
0.59	GO:0050819	negative regulation of coagulation
0.58	GO:1900047	negative regulation of hemostasis
0.58	GO:0044537	regulation of circulating fibrinogen levels
0.58	GO:0061045	negative regulation of wound healing
0.57	GO:0030193	regulation of blood coagulation
0.57	GO:0050728	negative regulation of inflammatory response

0.69	GO:0004252	serine-type endopeptidase activity
0.67	GO:0005509	calcium ion binding
0.38	GO:0070012	oligopeptidase activity
0.37	GO:0043621	protein self-association
0.36	GO:0005543	phospholipid binding
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0030247	polysaccharide binding
0.34	GO:0004143	diacylglycerol kinase activity
0.33	GO:0003951	NAD+ kinase activity
0.33	GO:0003677	DNA binding

0.64	GO:0005576	extracellular region
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005783	endoplasmic reticulum
0.39	GO:1905286	serine-type peptidase complex
0.34	GO:0043233	organelle lumen
0.34	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.32	GO:0030141	secretory granule
0.30	GO:0016020	membrane

0.69	EC:3.4.21	GO:0004252
0.33	KEGG:R00104	GO:0003951

sp|P31399|ATP5H_RAT
ATP synthase subunit d, mitochondrial
Search

ATP5H

0.74	ATP synthase subunit d, mitochondrial

0.69	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.69	GO:0006754	ATP biosynthetic process
0.49	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0042407	cristae formation
0.34	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport

0.62	GO:0015078	hydrogen ion transmembrane transporter activity
0.50	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.49	GO:0019829	cation-transporting ATPase activity

0.76	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.58	GO:0045265	proton-transporting ATP synthase, stator stalk
0.47	GO:0043209	myelin sheath
0.44	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome

sp|P31421|GRM2_RAT
Metabotropic glutamate receptor 2
Search

GRM2

0.92	Metabotropic glutamate receptor 2

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0007215	glutamate receptor signaling pathway
0.54	GO:0051966	regulation of synaptic transmission, glutamatergic
0.52	GO:0065009	regulation of molecular function
0.40	GO:0014047	glutamate secretion
0.37	GO:0030818	negative regulation of cAMP biosynthetic process
0.37	GO:0007268	chemical synaptic transmission
0.36	GO:0019233	sensory perception of pain
0.35	GO:0046928	regulation of neurotransmitter secretion
0.35	GO:0051930	regulation of sensory perception of pain

0.71	GO:0004930	G-protein coupled receptor activity
0.64	GO:0005246	calcium channel regulator activity
0.59	GO:0008066	glutamate receptor activity
0.35	GO:0005515	protein binding

0.57	GO:0043005	neuron projection
0.55	GO:0005886	plasma membrane
0.50	GO:0014069	postsynaptic density
0.50	GO:0036477	somatodendritic compartment
0.50	GO:0098793	presynapse
0.49	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0030054	cell junction
0.35	GO:0097449	astrocyte projection
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P31422|GRM3_RAT
Metabotropic glutamate receptor 3
Search

GRM3

0.96	Metabotropic glutamate receptor 3

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0007215	glutamate receptor signaling pathway
0.48	GO:0051966	regulation of synaptic transmission, glutamatergic
0.48	GO:0065009	regulation of molecular function
0.37	GO:0019233	sensory perception of pain
0.36	GO:0007268	chemical synaptic transmission
0.35	GO:0051930	regulation of sensory perception of pain
0.35	GO:0030818	negative regulation of cAMP biosynthetic process
0.35	GO:0014047	glutamate secretion

0.71	GO:0004930	G-protein coupled receptor activity
0.58	GO:0005246	calcium channel regulator activity
0.54	GO:0008066	glutamate receptor activity

0.56	GO:0042734	presynaptic membrane
0.55	GO:0043197	dendritic spine
0.54	GO:0014069	postsynaptic density
0.53	GO:0030424	axon
0.52	GO:0045211	postsynaptic membrane
0.42	GO:0005887	integral component of plasma membrane
0.36	GO:0097449	astrocyte projection
0.35	GO:0048786	presynaptic active zone
0.33	GO:0030054	cell junction
0.31	GO:0005622	intracellular

sp|P31423|GRM4_RAT
Metabotropic glutamate receptor 4
Search

GRM4

0.93	Metabotropic glutamate receptor 4

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0007215	glutamate receptor signaling pathway
0.52	GO:0000187	activation of MAPK activity
0.49	GO:0051966	regulation of synaptic transmission, glutamatergic
0.37	GO:0007268	chemical synaptic transmission
0.37	GO:0007612	learning
0.37	GO:0043523	regulation of neuron apoptotic process
0.36	GO:0006836	neurotransmitter transport
0.35	GO:0050805	negative regulation of synaptic transmission
0.35	GO:0046903	secretion

0.71	GO:0004930	G-protein coupled receptor activity
0.53	GO:0008066	glutamate receptor activity
0.35	GO:0048306	calcium-dependent protein binding
0.35	GO:0005516	calmodulin binding

0.55	GO:0005886	plasma membrane
0.47	GO:0031410	cytoplasmic vesicle
0.46	GO:0098793	presynapse
0.36	GO:0043005	neuron projection
0.35	GO:0036477	somatodendritic compartment
0.34	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

sp|P31424|GRM5_RAT
Metabotropic glutamate receptor 5
Search

GRM5

0.93	Metabotropic glutamate receptor 5 splice variant f

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.66	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration
0.66	GO:1902938	regulation of intracellular calcium activated chloride channel activity
0.65	GO:0090647	modulation of age-related behavioral decline
0.64	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.64	GO:1904646	cellular response to amyloid-beta
0.64	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.62	GO:0061098	positive regulation of protein tyrosine kinase activity
0.61	GO:0007612	learning
0.60	GO:0007626	locomotory behavior

0.72	GO:0004930	G-protein coupled receptor activity
0.67	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.59	GO:0008066	glutamate receptor activity
0.41	GO:1990782	protein tyrosine kinase binding
0.40	GO:0031687	A2A adenosine receptor binding
0.38	GO:0030296	protein tyrosine kinase activator activity
0.38	GO:0030165	PDZ domain binding
0.37	GO:0005516	calmodulin binding

0.60	GO:0098794	postsynapse
0.58	GO:0097458	neuron part
0.55	GO:0032279	asymmetric synapse
0.55	GO:0120025	plasma membrane bounded cell projection
0.55	GO:0005886	plasma membrane
0.41	GO:0043226	organelle
0.41	GO:0005737	cytoplasm
0.39	GO:0005615	extracellular space
0.36	GO:0044463	cell projection part
0.30	GO:0016021	integral component of membrane

sp|P31430|DPEP1_RAT
Dipeptidase 1
Search

DPEP1

0.58	Dipeptidase

0.60	GO:0006508	proteolysis
0.58	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:0030336	negative regulation of cell migration
0.57	GO:0050667	homocysteine metabolic process
0.56	GO:0035690	cellular response to drug
0.54	GO:0006915	apoptotic process
0.54	GO:0016999	antibiotic metabolic process
0.44	GO:0071731	response to nitric oxide
0.44	GO:1902170	cellular response to reactive nitrogen species
0.44	GO:0071277	cellular response to calcium ion

0.77	GO:0016805	dipeptidase activity
0.75	GO:0008239	dipeptidyl-peptidase activity
0.70	GO:0008235	metalloexopeptidase activity
0.60	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.54	GO:0046872	metal ion binding
0.53	GO:0072341	modified amino acid binding
0.45	GO:0034235	GPI anchor binding
0.33	GO:0005515	protein binding
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.78	GO:0031225	anchored component of membrane
0.56	GO:0045177	apical part of cell
0.51	GO:0030054	cell junction
0.45	GO:0005634	nucleus
0.44	GO:0005886	plasma membrane
0.42	GO:0005902	microvillus
0.41	GO:0005615	extracellular space
0.40	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:1903561	extracellular vesicle
0.34	GO:0005789	endoplasmic reticulum membrane

0.77

EC:3.4.13

GO:0016805

sp|P31503|PO2F1_RAT
POU domain, class 2, transcription factor 1 (Fragment)
Search

POU2F1

0.71	POU domain, class 2, transcription factor 1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.48	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process
0.48	GO:0031327	negative regulation of cellular biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001047	core promoter binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.37	GO:0001223	transcription coactivator binding
0.35	GO:0003682	chromatin binding
0.34	GO:0005102	receptor binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0043233	organelle lumen
0.43	GO:0044446	intracellular organelle part

sp|P31596|EAA2_RAT
Excitatory amino acid transporter 2
Search

SLC1A2

0.45	Amino acid transporter

0.58	GO:0070777	D-aspartate transport
0.57	GO:0098712	L-glutamate import across plasma membrane
0.55	GO:0070207	protein homotrimerization
0.55	GO:0046326	positive regulation of glucose import
0.55	GO:0007632	visual behavior
0.54	GO:0035264	multicellular organism growth
0.54	GO:0010259	multicellular organism aging
0.54	GO:0043200	response to amino acid
0.53	GO:0021537	telencephalon development
0.53	GO:0030534	adult behavior

0.72	GO:0015293	symporter activity
0.53	GO:0005313	L-glutamate transmembrane transporter activity
0.49	GO:0015081	sodium ion transmembrane transporter activity
0.47	GO:0022853	active ion transmembrane transporter activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.55	GO:0030673	axolemma
0.50	GO:0009986	cell surface
0.46	GO:0005887	integral component of plasma membrane
0.35	GO:0043198	dendritic shaft
0.35	GO:0042734	presynaptic membrane
0.35	GO:0043197	dendritic spine

sp|P31643|SC6A6_RAT
Sodium- and chloride-dependent taurine transporter
Search

SLC6A6

0.46	Sodium- and chloride-dependent taurine transporter

0.82	GO:0015734	taurine transport
0.76	GO:0006836	neurotransmitter transport
0.54	GO:0055085	transmembrane transport
0.42	GO:0006865	amino acid transport
0.33	GO:0006520	cellular amino acid metabolic process

0.86	GO:0005369	taurine:sodium symporter activity
0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.36	GO:0043210	alkanesulfonate binding
0.34	GO:0015171	amino acid transmembrane transporter activity

0.66

GO:0005887

integral component of plasma membrane

sp|P31646|S6A13_RAT
Sodium- and chloride-dependent GABA transporter 2
Search

SLC6A13

0.56	Solute carrier family 6 member 13

0.76	GO:0006836	neurotransmitter transport
0.57	GO:0015718	monocarboxylic acid transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0006865	amino acid transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.64	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.63	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.59	GO:0005283	sodium:amino acid symporter activity
0.58	GO:0015296	anion:cation symporter activity

0.54

GO:0005887

integral component of plasma membrane

sp|P31647|S6A11_RAT
Sodium- and chloride-dependent GABA transporter 3
Search

SLC6A11

0.44	Sodium- and chloride-dependent GABA transporter 3

0.76	GO:0006836	neurotransmitter transport
0.60	GO:0015718	monocarboxylic acid transport
0.57	GO:0006865	amino acid transport
0.55	GO:0055085	transmembrane transport
0.37	GO:0007420	brain development
0.36	GO:0042493	response to drug
0.32	GO:0006812	cation transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.68	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.67	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.62	GO:0005283	sodium:amino acid symporter activity
0.62	GO:0015296	anion:cation symporter activity
0.38	GO:0042165	neurotransmitter binding
0.34	GO:0015193	L-proline transmembrane transporter activity

0.56	GO:0005887	integral component of plasma membrane
0.36	GO:0042995	cell projection
0.33	GO:0005737	cytoplasm

sp|P31652|SC6A4_RAT
Sodium-dependent serotonin transporter
Search

SLC6A4

0.48	Sodium-dependent serotonin transporter

0.81	GO:0006837	serotonin transport
0.67	GO:0090067	regulation of thalamus size
0.62	GO:0098810	neurotransmitter reuptake
0.57	GO:0046621	negative regulation of organ growth
0.57	GO:0035176	social behavior
0.57	GO:0048854	brain morphogenesis
0.55	GO:0055085	transmembrane transport
0.53	GO:0045787	positive regulation of cell cycle
0.51	GO:0090494	dopamine uptake
0.50	GO:0001963	synaptic transmission, dopaminergic

0.82	GO:0015222	serotonin transmembrane transporter activity
0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.59	GO:0050998	nitric-oxide synthase binding
0.54	GO:0017137	Rab GTPase binding
0.51	GO:0005329	dopamine transmembrane transporter activity
0.40	GO:0019811	cocaine binding
0.40	GO:0051015	actin filament binding
0.39	GO:0017075	syntaxin-1 binding
0.38	GO:0017022	myosin binding
0.37	GO:0051378	serotonin binding

0.60	GO:0005887	integral component of plasma membrane
0.55	GO:0098793	presynapse
0.54	GO:0045121	membrane raft
0.48	GO:0005829	cytosol
0.48	GO:0012505	endomembrane system
0.46	GO:0043005	neuron projection
0.39	GO:0044433	cytoplasmic vesicle part
0.39	GO:0098588	bounding membrane of organelle
0.36	GO:0016324	apical plasma membrane

sp|P31662|S6A17_RAT
Sodium-dependent neutral amino acid transporter SLC6A17
Search

SLC6A17

0.57	Sodium-dependent neutral amino acid transporter SLC6A17

0.76	GO:0006836	neurotransmitter transport
0.62	GO:0015820	leucine transport
0.56	GO:0015824	proline transport
0.55	GO:0055085	transmembrane transport
0.53	GO:0015807	L-amino acid transport
0.53	GO:0032328	alanine transport
0.52	GO:0007420	brain development
0.49	GO:0015893	drug transport
0.39	GO:0006814	sodium ion transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.51	GO:0015171	amino acid transmembrane transporter activity
0.40	GO:0005343	organic acid:sodium symporter activity
0.40	GO:0015296	anion:cation symporter activity
0.39	GO:0015238	drug transmembrane transporter activity

0.65	GO:0005887	integral component of plasma membrane
0.56	GO:0030672	synaptic vesicle membrane
0.51	GO:0030054	cell junction

sp|P31720|C1QA_RAT
Complement C1q subcomponent subunit A
Search

C1QA

0.92	Complement component 1, q subcomponent, A chain

0.78	GO:0006958	complement activation, classical pathway
0.42	GO:0010039	response to iron ion
0.42	GO:0045087	innate immune response
0.39	GO:0007155	cell adhesion
0.38	GO:0007275	multicellular organism development
0.37	GO:0051093	negative regulation of developmental process
0.37	GO:0051241	negative regulation of multicellular organismal process
0.37	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.37	GO:2000026	regulation of multicellular organismal development
0.37	GO:0007492	endoderm development

0.50	GO:0005201	extracellular matrix structural constituent
0.37	GO:0005515	protein binding
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0042302	structural constituent of cuticle
0.32	GO:0044877	macromolecular complex binding
0.32	GO:0005509	calcium ion binding

0.77	GO:0005581	collagen trimer
0.64	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.36	GO:0099081	supramolecular polymer
0.33	GO:0005788	endoplasmic reticulum lumen
0.32	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0004252

sp|P31721|C1QB_RAT
Complement C1q subcomponent subunit B
Search

C1QB

0.96	Complement 1 subcomponent q polypeptide beta (Fragment)

0.72	GO:0006958	complement activation, classical pathway
0.57	GO:0048839	inner ear development
0.50	GO:0045650	negative regulation of macrophage differentiation
0.50	GO:0030853	negative regulation of granulocyte differentiation
0.41	GO:0045087	innate immune response
0.38	GO:0030449	regulation of complement activation
0.37	GO:0051384	response to glucocorticoid
0.36	GO:0007568	aging
0.36	GO:0007420	brain development
0.34	GO:0006508	proteolysis

0.53	GO:0042803	protein homodimerization activity
0.36	GO:0004252	serine-type endopeptidase activity

0.71	GO:0005581	collagen trimer
0.61	GO:0005576	extracellular region
0.38	GO:0031982	vesicle

0.36

GO:0004252

sp|P31722|C1QC_RAT
Complement C1q subcomponent subunit C
Search

C1QC

0.96	Complement 1 subcomponent q polypeptide gamma (Fragment)

0.61	GO:0045650	negative regulation of macrophage differentiation
0.61	GO:0030853	negative regulation of granulocyte differentiation
0.56	GO:0006958	complement activation, classical pathway
0.43	GO:0048839	inner ear development
0.41	GO:0045087	innate immune response
0.37	GO:0030449	regulation of complement activation
0.37	GO:0051259	protein oligomerization
0.35	GO:0052548	regulation of endopeptidase activity
0.34	GO:0051384	response to glucocorticoid
0.34	GO:0006508	proteolysis

0.43	GO:0042802	identical protein binding
0.40	GO:0005201	extracellular matrix structural constituent
0.40	GO:0046983	protein dimerization activity
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0005178	integrin binding
0.33	GO:0042302	structural constituent of cuticle

0.76	GO:0005581	collagen trimer
0.64	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0099081	supramolecular polymer
0.32	GO:0005829	cytosol
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0005634	nucleus
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.35

GO:0004252

sp|P31977|EZRI_RAT
Ezrin
Search

EZR

0.97	Epididymis secretory protein Li 105

0.56	GO:1902965	regulation of protein localization to early endosome
0.56	GO:2000643	positive regulation of early endosome to late endosome transport
0.56	GO:1905668	positive regulation of protein localization to endosome
0.55	GO:0022614	membrane to membrane docking
0.55	GO:0061028	establishment of endothelial barrier
0.53	GO:1900041	negative regulation of interleukin-2 secretion
0.53	GO:0007159	leukocyte cell-cell adhesion
0.53	GO:1902896	terminal web assembly
0.53	GO:0030033	microvillus assembly
0.53	GO:0001951	intestinal D-glucose absorption

0.73	GO:0003779	actin binding
0.52	GO:0051117	ATPase binding
0.52	GO:0050839	cell adhesion molecule binding
0.52	GO:0034236	protein kinase A catalytic subunit binding
0.51	GO:0044548	S100 protein binding
0.51	GO:0034237	protein kinase A regulatory subunit binding
0.51	GO:0097718	disordered domain specific binding
0.50	GO:0008022	protein C-terminus binding
0.47	GO:0032403	protein complex binding
0.46	GO:0008017	microtubule binding

0.69	GO:0005856	cytoskeleton
0.55	GO:0071437	invadopodium
0.54	GO:0005902	microvillus
0.53	GO:0001931	uropod
0.53	GO:0030175	filopodium
0.53	GO:0016324	apical plasma membrane
0.52	GO:0005925	focal adhesion
0.51	GO:0043209	myelin sheath
0.51	GO:0001772	immunological synapse
0.51	GO:0001726	ruffle

0.34

GO:0004714

sp|P32038|CFAD_RAT
Complement factor D
Search

CFD

0.75	Complement factor D

0.73	GO:0006957	complement activation, alternative pathway
0.61	GO:0006508	proteolysis
0.44	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.43	GO:0070997	neuron death
0.37	GO:0051239	regulation of multicellular organismal process
0.37	GO:0032501	multicellular organismal process
0.36	GO:0048856	anatomical structure development
0.36	GO:0007219	Notch signaling pathway
0.36	GO:0022617	extracellular matrix disassembly
0.36	GO:0002576	platelet degranulation

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:1904854	proteasome core complex binding
0.34	GO:1990405	protein antigen binding
0.34	GO:0034185	apolipoprotein binding
0.34	GO:0008201	heparin binding
0.33	GO:0019900	kinase binding
0.33	GO:0051087	chaperone binding
0.33	GO:0019904	protein domain specific binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005102	receptor binding

0.50	GO:0005615	extracellular space
0.40	GO:0030141	secretory granule
0.38	GO:1903561	extracellular vesicle
0.37	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005766	primary lysosome
0.34	GO:0005775	vacuolar lumen
0.34	GO:0031232	extrinsic component of external side of plasma membrane
0.33	GO:0005730	nucleolus
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0044218	other organism cell membrane

0.69

GO:0004252

sp|P32089|TXTP_RAT
Tricarboxylate transport protein, mitochondrial
Search

SLC25A1

0.48	Plasma membrane citrate carrier

0.51	GO:0006843	mitochondrial citrate transport
0.49	GO:0055085	transmembrane transport
0.40	GO:0010821	regulation of mitochondrion organization
0.39	GO:0048268	clathrin coat assembly
0.37	GO:0006886	intracellular protein transport
0.37	GO:0016192	vesicle-mediated transport
0.36	GO:0046326	positive regulation of glucose import
0.36	GO:0016482	cytosolic transport
0.35	GO:0016197	endosomal transport
0.35	GO:0000278	mitotic cell cycle

0.49	GO:0015137	citrate transmembrane transporter activity
0.39	GO:0032051	clathrin light chain binding
0.35	GO:0005198	structural molecule activity

0.44	GO:0031090	organelle membrane
0.43	GO:0005740	mitochondrial envelope
0.39	GO:0071439	clathrin complex
0.39	GO:0030140	trans-Golgi network transport vesicle
0.39	GO:0030132	clathrin coat of coated pit
0.38	GO:0044433	cytoplasmic vesicle part
0.37	GO:0044431	Golgi apparatus part
0.37	GO:0097443	sorting endosome
0.36	GO:0070062	extracellular exosome
0.36	GO:0005770	late endosome

sp|P32182|FOXA2_RAT
Hepatocyte nuclear factor 3-beta
Search

FOXA2

0.95	Hepatocyte nuclear factor 3-alpha

0.60	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.58	GO:0071542	dopaminergic neuron differentiation
0.57	GO:0031018	endocrine pancreas development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:1900046	regulation of hemostasis
0.56	GO:0050818	regulation of coagulation
0.56	GO:0061041	regulation of wound healing
0.53	GO:1902680	positive regulation of RNA biosynthetic process

0.76	GO:0019904	protein domain specific binding
0.72	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0044212	transcription regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.36	GO:0046332	SMAD binding
0.35	GO:0019900	kinase binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.51	GO:0030054	cell junction
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.40	GO:0005902	microvillus
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005737	cytoplasm

sp|P32183|FOXA3_RAT
Hepatocyte nuclear factor 3-gamma
Search

FOXA3

0.83	Forkhead box protein A2

0.70	GO:0042593	glucose homeostasis
0.66	GO:0045944	positive regulation of transcription by RNA polymerase II
0.65	GO:0007283	spermatogenesis
0.64	GO:0009267	cellular response to starvation
0.60	GO:0055082	cellular chemical homeostasis
0.56	GO:0009653	anatomical structure morphogenesis
0.55	GO:1902691	respiratory basal cell differentiation
0.55	GO:0021915	neural tube development
0.55	GO:0061144	alveolar secondary septum development
0.54	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development

0.73	GO:0019904	protein domain specific binding
0.69	GO:0008134	transcription factor binding
0.67	GO:0044212	transcription regulatory region DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003690	double-stranded DNA binding

0.62	GO:0005654	nucleoplasm
0.61	GO:0015629	actin cytoskeleton
0.51	GO:0005902	microvillus
0.51	GO:0001650	fibrillar center

sp|P32198|CPT1A_RAT
Carnitine O-palmitoyltransferase 1, liver isoform
Search

CPT1A

0.89	Carnitine O-palmitoyltransferase

0.53	GO:0009437	carnitine metabolic process
0.51	GO:0001676	long-chain fatty acid metabolic process
0.51	GO:0030855	epithelial cell differentiation
0.42	GO:0032000	positive regulation of fatty acid beta-oxidation
0.42	GO:0042755	eating behavior
0.41	GO:0071398	cellular response to fatty acid
0.41	GO:0050796	regulation of insulin secretion
0.40	GO:0006641	triglyceride metabolic process
0.39	GO:0051260	protein homooligomerization
0.39	GO:0014070	response to organic cyclic compound

0.63	GO:0016746	transferase activity, transferring acyl groups
0.39	GO:0042802	identical protein binding

0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.40	GO:0031968	organelle outer membrane
0.39	GO:0031301	integral component of organelle membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005840	ribosome

0.63

EC:2.3

GO:0016746

sp|P32214|CALCR_RAT
Calcitonin receptor
Search

CALCR

0.76	Calcitonin receptor

0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0019933	cAMP-mediated signaling
0.55	GO:0030316	osteoclast differentiation
0.55	GO:0030279	negative regulation of ossification
0.54	GO:0043488	regulation of mRNA stability
0.53	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.42	GO:0031623	receptor internalization
0.42	GO:0010739	positive regulation of protein kinase A signaling
0.42	GO:0045762	positive regulation of adenylate cyclase activity

0.85	GO:0004948	calcitonin receptor activity
0.46	GO:0097644	calcitonin family binding
0.43	GO:0097643	amylin receptor activity
0.41	GO:0001635	calcitonin gene-related peptide receptor activity
0.41	GO:0001605	adrenomedullin receptor activity
0.41	GO:0008565	protein transporter activity
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.54	GO:0001669	acrosomal vesicle
0.51	GO:0005929	cilium
0.50	GO:0005886	plasma membrane
0.43	GO:0043235	receptor complex
0.38	GO:0005764	lysosome
0.38	GO:0005768	endosome
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0043025	neuronal cell body
0.37	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|P32215|PACR_RAT
Pituitary adenylate cyclase-activating polypeptide type I receptor
Search

ADCYAP1R1

0.86	Pituitary adenylate cyclase-activating polypeptide type IA receptor

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0060732	positive regulation of inositol phosphate biosynthetic process
0.40	GO:0043950	positive regulation of cAMP-mediated signaling
0.40	GO:0007202	activation of phospholipase C activity
0.40	GO:0010524	positive regulation of calcium ion transport into cytosol
0.40	GO:0032355	response to estradiol
0.40	GO:0033555	multicellular organismal response to stress
0.40	GO:0051057	positive regulation of small GTPase mediated signal transduction
0.40	GO:0045471	response to ethanol

0.86	GO:0004999	vasoactive intestinal polypeptide receptor activity
0.42	GO:0001634	pituitary adenylate cyclase-activating polypeptide receptor activity
0.40	GO:0008179	adenylate cyclase binding
0.40	GO:0042923	neuropeptide binding
0.40	GO:0030306	ADP-ribosylation factor binding

0.57	GO:0043235	receptor complex
0.53	GO:0005886	plasma membrane
0.45	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0005923	bicellular tight junction
0.39	GO:0045121	membrane raft
0.38	GO:0043005	neuron projection
0.38	GO:0009986	cell surface
0.38	GO:0005768	endosome
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment

sp|P32232|CBS_RAT
Cystathionine beta-synthase
Search

CBS

0.62	Cystathionine beta-synthase

0.84	GO:0019343	cysteine biosynthetic process via cystathionine
0.76	GO:0006535	cysteine biosynthetic process from serine
0.56	GO:0051593	response to folic acid
0.54	GO:0001958	endochondral ossification
0.54	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.54	GO:0001974	blood vessel remodeling
0.54	GO:0030823	regulation of cGMP metabolic process
0.53	GO:0021587	cerebellum morphogenesis
0.53	GO:0043506	regulation of JUN kinase activity
0.53	GO:0050667	homocysteine metabolic process

0.84	GO:0004122	cystathionine beta-synthase activity
0.42	GO:0030170	pyridoxal phosphate binding
0.40	GO:0020037	heme binding
0.39	GO:0070025	carbon monoxide binding
0.39	GO:0070026	nitric oxide binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0050421	nitrite reductase (NO-forming) activity
0.37	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0019825	oxygen binding
0.37	GO:1904047	S-adenosyl-L-methionine binding

0.49	GO:0005737	cytoplasm
0.37	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.84

EC:4.2.1.22

GO:0004122

sp|P32244|MC3R_RAT
Melanocortin receptor 3
Search

MC3R

0.97	Melanocortin receptor 3

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0019933	cAMP-mediated signaling
0.54	GO:0060259	regulation of feeding behavior
0.54	GO:0045475	locomotor rhythm
0.53	GO:0032922	circadian regulation of gene expression
0.41	GO:0042309	homoiothermy
0.40	GO:0055078	sodium ion homeostasis
0.39	GO:0002027	regulation of heart rate
0.39	GO:0008217	regulation of blood pressure
0.35	GO:0030819	positive regulation of cAMP biosynthetic process

0.84	GO:0004977	melanocortin receptor activity
0.55	GO:0042923	neuropeptide binding
0.41	GO:0042562	hormone binding
0.35	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P32301|GLP1R_RAT
Glucagon-like peptide 1 receptor
Search

GLP1R

0.96	Glucagon like peptide 1 receptor

0.83	GO:0071377	cellular response to glucagon stimulus
0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0019933	cAMP-mediated signaling
0.57	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0045777	positive regulation of blood pressure
0.51	GO:0008016	regulation of heart contraction
0.51	GO:0007611	learning or memory
0.46	GO:0010906	regulation of glucose metabolic process
0.44	GO:0006950	response to stress

0.84	GO:0004967	glucagon receptor activity
0.64	GO:0044508	glucagon-like peptide 1 receptor activity
0.54	GO:0016519	gastric inhibitory peptide receptor activity
0.44	GO:0017046	peptide hormone binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0005515	protein binding

0.51	GO:0005886	plasma membrane
0.39	GO:0005622	intracellular
0.34	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.33	GO:1902494	catalytic complex
0.33	GO:0043234	protein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

sp|P32305|5HT7R_RAT
5-hydroxytryptamine receptor 7
Search

HTR7

0.91	Serotonin 5-hydroxytryptamine 7-a receptor

0.84	GO:0006939	smooth muscle contraction
0.83	GO:0042310	vasoconstriction
0.83	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.80	GO:0007623	circadian rhythm
0.76	GO:0007268	chemical synaptic transmission
0.46	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.37	GO:0007192	adenylate cyclase-activating serotonin receptor signaling pathway
0.36	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep
0.36	GO:0014063	negative regulation of serotonin secretion
0.36	GO:0051412	response to corticosterone

0.83	GO:0099589	serotonin receptor activity
0.80	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.80	GO:0008227	G-protein coupled amine receptor activity
0.47	GO:0051378	serotonin binding

0.49	GO:0005887	integral component of plasma membrane
0.35	GO:0043679	axon terminus
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0008021	synaptic vesicle
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite

sp|P32362|DCUP_RAT
Uroporphyrinogen decarboxylase (Fragment)
Search

UROD

0.49	Uroporphyrinogen decarboxylase

0.72	GO:0006782	protoporphyrinogen IX biosynthetic process
0.36	GO:0046502	uroporphyrinogen III metabolic process
0.36	GO:0051597	response to methylmercury
0.36	GO:0060992	response to fungicide
0.36	GO:0071243	cellular response to arsenic-containing substance
0.36	GO:0014075	response to amine
0.35	GO:0032355	response to estradiol
0.35	GO:0010039	response to iron ion
0.35	GO:0045471	response to ethanol
0.35	GO:0001889	liver development

0.78	GO:0004853	uroporphyrinogen decarboxylase activity
0.35	GO:0008198	ferrous iron binding
0.33	GO:0005515	protein binding

0.50	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm

0.78

EC:4.1.1.37

GO:0004853

sp|P32551|QCR2_RAT
Cytochrome b-c1 complex subunit 2, mitochondrial
Search

UQCRC2

0.83	Ubiquinol-cytochrome c reductase core protein II

0.51	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.34	GO:0022900	electron transport chain

0.58	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.34	GO:0009055	electron transfer activity

0.60	GO:0005750	mitochondrial respiratory chain complex III
0.59	GO:0005751	mitochondrial respiratory chain complex IV
0.59	GO:0043209	myelin sheath
0.51	GO:0005654	nucleoplasm

0.58

GO:0004222

sp|P32577|CSK_RAT
Tyrosine-protein kinase CSK
Search

CSK

0.59	Tyrosine-protein kinase

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.57	GO:0042997	negative regulation of Golgi to plasma membrane protein transport
0.51	GO:0042127	regulation of cell proliferation
0.49	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway
0.46	GO:0034332	adherens junction organization
0.45	GO:0060027	convergent extension involved in gastrulation
0.45	GO:0046777	protein autophosphorylation
0.44	GO:0001817	regulation of cytokine production
0.44	GO:0007417	central nervous system development
0.44	GO:0045087	innate immune response

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0034236	protein kinase A catalytic subunit binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.42	GO:0005102	receptor binding
0.35	GO:0070064	proline-rich region binding
0.35	GO:0019903	protein phosphatase binding
0.35	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

0.49	GO:0005911	cell-cell junction
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0098857	membrane microdomain
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0004715

sp|P32736|OPCM_RAT
Opioid-binding protein/cell adhesion molecule
Search

OPCML

0.87	Opioid binding protein/cell adhesion molecule like

0.63	GO:0007155	cell adhesion
0.52	GO:0006501	C-terminal protein lipidation
0.50	GO:0008038	neuron recognition
0.44	GO:0032355	response to estradiol
0.44	GO:0021549	cerebellum development
0.44	GO:0010977	negative regulation of neuron projection development

0.42

GO:0005515

protein binding

0.69	GO:0031225	anchored component of membrane
0.50	GO:0005886	plasma membrane
0.50	GO:0070062	extracellular exosome
0.44	GO:0060076	excitatory synapse
0.42	GO:0030424	axon
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P32738|CLAT_RAT
Choline O-acetyltransferase
Search

CHAT

0.96	Choline O-acetyltransferase a

0.55	GO:0060416	response to growth hormone
0.43	GO:0007626	locomotory behavior
0.40	GO:0042136	neurotransmitter biosynthetic process
0.39	GO:0007529	establishment of synaptic specificity at neuromuscular junction
0.39	GO:0043179	rhythmic excitation
0.38	GO:0007268	chemical synaptic transmission
0.38	GO:0007622	rhythmic behavior
0.37	GO:0016358	dendrite development
0.37	GO:0030534	adult behavior
0.37	GO:0007517	muscle organ development

0.62	GO:0016746	transferase activity, transferring acyl groups
0.35	GO:0033265	choline binding

0.37	GO:0097458	neuron part
0.37	GO:0044297	cell body
0.36	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0044456	synapse part
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part

0.62

EC:2.3

GO:0016746

sp|P32755|HPPD_RAT
4-hydroxyphenylpyruvate dioxygenase
Search

HPD

0.58	4-hydroxyphenylpyruvate dioxygenase

0.69	GO:0009072	aromatic amino acid family metabolic process
0.53	GO:0055114	oxidation-reduction process
0.44	GO:1901606	alpha-amino acid catabolic process
0.43	GO:1901361	organic cyclic compound catabolic process
0.43	GO:0019439	aromatic compound catabolic process
0.40	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process
0.38	GO:0042737	drug catabolic process
0.33	GO:0032392	DNA geometric change
0.33	GO:0006260	DNA replication

0.82	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
0.52	GO:0046872	metal ion binding
0.45	GO:0004462	lactoylglutathione lyase activity
0.33	GO:0003678	DNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0000139	Golgi membrane
0.44	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.82	EC:1.13.11.27	GO:0003868
0.45	KEGG:R02530	GO:0004462

sp|P32821|TRYA_RAT
Trypsin V-A
Search

0.46	Cationic trypsinogen

0.61	GO:0006508	proteolysis
0.51	GO:0007586	digestion
0.38	GO:0043542	endothelial cell migration
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.37	GO:0030574	collagen catabolic process
0.37	GO:0035094	response to nicotine
0.35	GO:0051604	protein maturation
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0022617	extracellular matrix disassembly

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005509	calcium ion binding
0.35	GO:0097655	serpin family protein binding
0.33	GO:0046982	protein heterodimerization activity

0.51	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0097180	serine protease inhibitor complex
0.35	GO:1904724	tertiary granule lumen
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P32822|TRYB_RAT
Trypsin V-B
Search

0.46	Cationic trypsinogen

0.61	GO:0006508	proteolysis
0.51	GO:0007586	digestion
0.38	GO:0043542	endothelial cell migration
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.37	GO:0030574	collagen catabolic process
0.37	GO:0035094	response to nicotine
0.35	GO:0051604	protein maturation
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0022617	extracellular matrix disassembly

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0005509	calcium ion binding
0.35	GO:0097655	serpin family protein binding
0.33	GO:0046982	protein heterodimerization activity

0.51	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0097180	serine protease inhibitor complex
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P32851|STX1A_RAT
Syntaxin-1A
Search

STX1A

0.74	Syntaxin-1A isoform A

0.78	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.62	GO:0001956	positive regulation of neurotransmitter secretion
0.61	GO:2000463	positive regulation of excitatory postsynaptic potential
0.61	GO:1902803	regulation of synaptic vesicle transport
0.60	GO:0098693	regulation of synaptic vesicle cycle
0.55	GO:0097480	establishment of synaptic vesicle localization
0.55	GO:0099504	synaptic vesicle cycle

0.80	GO:0005484	SNAP receptor activity
0.76	GO:0000149	SNARE binding
0.55	GO:0019900	kinase binding
0.54	GO:0019869	chloride channel inhibitor activity
0.53	GO:0019855	calcium channel inhibitor activity
0.46	GO:0017022	myosin binding
0.45	GO:0005102	receptor binding
0.41	GO:0043008	ATP-dependent protein binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0048306	calcium-dependent protein binding

0.57	GO:0098793	presynapse
0.57	GO:0031201	SNARE complex
0.56	GO:0030424	axon
0.55	GO:0070382	exocytic vesicle
0.49	GO:0030658	transport vesicle membrane
0.49	GO:0031965	nuclear membrane
0.45	GO:0005887	integral component of plasma membrane
0.41	GO:0097060	synaptic membrane
0.40	GO:0034705	potassium channel complex
0.40	GO:0042641	actomyosin

sp|P33124|ACSL6_RAT
Long-chain-fatty-acid--CoA ligase 6
Search

ACSL6

0.92	Long-chain-fatty-acid--CoA ligase 6

0.44	GO:0007405	neuroblast proliferation
0.44	GO:0001676	long-chain fatty acid metabolic process
0.39	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport
0.38	GO:0010867	positive regulation of triglyceride biosynthetic process
0.38	GO:0009629	response to gravity
0.37	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.37	GO:0032869	cellular response to insulin stimulus
0.37	GO:0010976	positive regulation of neuron projection development
0.37	GO:0001666	response to hypoxia
0.37	GO:0007584	response to nutrient

0.61	GO:0016874	ligase activity
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0019899	enzyme binding
0.36	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004359	glutaminase activity

0.41	GO:0031903	microbody membrane
0.41	GO:0044439	peroxisomal part
0.40	GO:0005741	mitochondrial outer membrane
0.39	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.61

GO:0016874

sp|P33272|CP2BC_RAT
Cytochrome P450 2B12
Search

CYP2B

0.97	Testosterone 16a-hydroxylase type b

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0019373	epoxygenase P450 pathway
0.47	GO:0042738	exogenous drug catabolic process
0.44	GO:0006805	xenobiotic metabolic process
0.43	GO:0008202	steroid metabolic process
0.41	GO:0042180	cellular ketone metabolic process
0.38	GO:0014070	response to organic cyclic compound
0.36	GO:0051592	response to calcium ion
0.36	GO:0010477	response to sulfur dioxide
0.36	GO:0018933	nicotine metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.51	GO:0008392	arachidonic acid epoxygenase activity
0.50	GO:0008395	steroid hydroxylase activity
0.37	GO:0019825	oxygen binding
0.34	GO:0004721	phosphoprotein phosphatase activity

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P33273|CP255_RAT
Cytochrome P450 2C55
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.66	GO:0042738	exogenous drug catabolic process
0.58	GO:0070989	oxidative demethylation
0.57	GO:0002933	lipid hydroxylation
0.57	GO:0008202	steroid metabolic process
0.55	GO:0019369	arachidonic acid metabolic process
0.55	GO:0016098	monoterpenoid metabolic process
0.44	GO:0043651	linoleic acid metabolic process
0.43	GO:0019627	urea metabolic process
0.35	GO:0046483	heterocycle metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0008395	steroid hydroxylase activity
0.65	GO:0034875	caffeine oxidase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.42	GO:0019899	enzyme binding
0.38	GO:0008144	drug binding

0.39	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.68

GO:0016705

sp|P33274|CP4F1_RAT
Cytochrome P450 4F1
Search

0.84	Cytochrome P450, family 4, subfamily F, polypeptide 2

0.61	GO:0042361	menaquinone catabolic process
0.61	GO:0042377	vitamin K catabolic process
0.61	GO:0042376	phylloquinone catabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0006631	fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.56	GO:0005504	fatty acid binding

0.30

GO:0031224

intrinsic component of membrane

0.68

GO:0016705

sp|P33436|MMP2_RAT
72 kDa type IV collagenase
Search

MMP2

0.44	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.44	GO:0001957	intramembranous ossification
0.44	GO:0060346	bone trabecula formation
0.44	GO:0001955	blood vessel maturation
0.44	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.44	GO:0007566	embryo implantation
0.44	GO:0030574	collagen catabolic process
0.43	GO:0060325	face morphogenesis
0.43	GO:0035987	endodermal cell differentiation
0.43	GO:0071230	cellular response to amino acid stimulus

0.70	GO:0004222	metalloendopeptidase activity
0.61	GO:0008270	zinc ion binding
0.30	GO:0005515	protein binding
0.30	GO:0004252	serine-type endopeptidase activity

0.72	GO:0031012	extracellular matrix
0.42	GO:0030017	sarcomere
0.40	GO:0005615	extracellular space
0.37	GO:0005739	mitochondrion
0.36	GO:0005886	plasma membrane
0.30	GO:0005634	nucleus

0.70

GO:0004222

sp|P33533|OPRD_RAT
Delta-type opioid receptor
Search

OPRD1

0.97	Delta-type opioid receptor

0.86	GO:0038003	opioid receptor signaling pathway
0.62	GO:0007218	neuropeptide signaling pathway
0.58	GO:0032460	negative regulation of protein oligomerization
0.57	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.56	GO:0000060	protein import into nucleus, translocation
0.56	GO:0030534	adult behavior
0.56	GO:0051881	regulation of mitochondrial membrane potential
0.56	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.55	GO:0071456	cellular response to hypoxia
0.55	GO:0007626	locomotory behavior

0.86	GO:0004985	opioid receptor activity
0.52	GO:0004977	melanocortin receptor activity
0.52	GO:0008188	neuropeptide receptor activity
0.52	GO:0042923	neuropeptide binding
0.52	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.44	GO:0001965	G-protein alpha-subunit binding
0.41	GO:0031681	G-protein beta-subunit binding
0.37	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0031005	filamin binding
0.34	GO:0008022	protein C-terminus binding

0.49	GO:0031226	intrinsic component of plasma membrane
0.48	GO:0043005	neuron projection
0.42	GO:0045203	integral component of cell outer membrane
0.41	GO:0036477	somatodendritic compartment
0.40	GO:0031256	leading edge membrane
0.40	GO:0031253	cell projection membrane
0.40	GO:0098857	membrane microdomain
0.39	GO:0098794	postsynapse
0.39	GO:0031982	vesicle
0.39	GO:0097060	synaptic membrane

sp|P33535|OPRM_RAT
Mu-type opioid receptor
Search

OPRM1

0.97	Mu opioid receptor variant

0.85	GO:0038003	opioid receptor signaling pathway
0.79	GO:0007218	neuropeptide signaling pathway
0.60	GO:0061358	negative regulation of Wnt protein secretion
0.57	GO:0019233	sensory perception of pain
0.55	GO:0071315	cellular response to morphine
0.54	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.53	GO:0048149	behavioral response to ethanol
0.52	GO:0050769	positive regulation of neurogenesis
0.52	GO:0007212	dopamine receptor signaling pathway
0.51	GO:0019933	cAMP-mediated signaling

0.86	GO:0004979	beta-endorphin receptor activity
0.58	GO:0001965	G-protein alpha-subunit binding
0.55	GO:0038047	morphine receptor activity
0.49	GO:0031681	G-protein beta-subunit binding
0.49	GO:0042923	neuropeptide binding
0.45	GO:0038046	enkephalin receptor activity
0.43	GO:0005245	voltage-gated calcium channel activity
0.39	GO:0031005	filamin binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.46	GO:0043005	neuron projection
0.44	GO:0043204	perikaryon
0.42	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0005768	endosome
0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0042383	sarcolemma
0.38	GO:0031256	leading edge membrane
0.38	GO:0005925	focal adhesion
0.38	GO:0098857	membrane microdomain
0.37	GO:0098794	postsynapse

sp|P33568|RB_RAT
Retinoblastoma-associated protein
Search

RB1

0.96	RB transcriptional corepressor 1

0.85	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.79	GO:0008285	negative regulation of cell proliferation
0.78	GO:0006915	apoptotic process
0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.61	GO:0043353	enucleate erythrocyte differentiation
0.61	GO:0045651	positive regulation of macrophage differentiation
0.60	GO:0071922	regulation of cohesin loading
0.60	GO:0034088	maintenance of mitotic sister chromatid cohesion
0.59	GO:0045445	myoblast differentiation

0.73	GO:0008134	transcription factor binding
0.60	GO:0061676	importin-alpha family protein binding
0.58	GO:0097718	disordered domain specific binding
0.57	GO:0051219	phosphoprotein binding
0.56	GO:0001047	core promoter binding
0.54	GO:0019900	kinase binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0042802	identical protein binding
0.35	GO:0051427	hormone receptor binding
0.35	GO:0003713	transcription coactivator activity

0.86	GO:0035189	Rb-E2F complex
0.59	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.58	GO:0016605	PML body
0.54	GO:0005819	spindle
0.35	GO:0016514	SWI/SNF complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P33578|PR8A7_RAT
Prolactin-8A7
Search

0.97	Prolactin-like protein-C variant

0.76	GO:0010469	regulation of receptor activity
0.50	GO:0007565	female pregnancy
0.42	GO:0001666	response to hypoxia
0.40	GO:0048609	multicellular organismal reproductive process
0.36	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.36	GO:0001937	negative regulation of endothelial cell proliferation
0.36	GO:0046427	positive regulation of JAK-STAT cascade
0.36	GO:0040014	regulation of multicellular organism growth

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P33579|PR8A5_RAT
Prolactin-8A5
Search

0.97	Prolactin-like protein-C variant

0.76	GO:0010469	regulation of receptor activity
0.50	GO:0007565	female pregnancy
0.40	GO:0001666	response to hypoxia
0.39	GO:0048609	multicellular organismal reproductive process

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P33580|PR8A4_RAT
Prolactin-8A4
Search

0.97	Prolactin-like protein-C variant

0.76	GO:0010469	regulation of receptor activity
0.50	GO:0007565	female pregnancy
0.42	GO:0001666	response to hypoxia
0.41	GO:0048609	multicellular organismal reproductive process

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P33581|GHR4_RAT
Growth hormone-related protein 4 (Fragment)
Search

0.19	Growth hormone-related protein 4 (Fragment)

0.76	GO:0010469	regulation of receptor activity
0.57	GO:0007565	female pregnancy

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P33671|SDC3_RAT
Syndecan-3
Search

SDC3

0.82

Syndecan

0.47	GO:0016477	cell migration
0.43	GO:0042060	wound healing
0.42	GO:0048627	myoblast development
0.42	GO:1903553	positive regulation of extracellular exosome assembly
0.41	GO:1903543	positive regulation of exosomal secretion
0.40	GO:0060070	canonical Wnt signaling pathway
0.40	GO:0055002	striated muscle cell development
0.39	GO:0003419	growth plate cartilage chondrocyte proliferation
0.37	GO:0035988	chondrocyte proliferation
0.37	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading

0.54	GO:0042802	identical protein binding
0.40	GO:0008022	protein C-terminus binding
0.35	GO:0019838	growth factor binding
0.33	GO:0050840	extracellular matrix binding

0.53	GO:0031012	extracellular matrix
0.48	GO:0009986	cell surface
0.40	GO:0005796	Golgi lumen
0.38	GO:0098552	side of membrane
0.37	GO:0043202	lysosomal lumen
0.36	GO:0005886	plasma membrane
0.36	GO:0030424	axon
0.35	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P34058|HS90B_RAT
Heat shock protein HSP 90-beta
Search

HSP90AB1

0.71	Heat shock cognate protein HSP 90-beta

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.59	GO:1901389	negative regulation of transforming growth factor beta activation
0.56	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.56	GO:1905323	telomerase holoenzyme complex assembly
0.55	GO:0071157	negative regulation of cell cycle arrest
0.55	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.54	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.54	GO:2000010	positive regulation of protein localization to cell surface
0.54	GO:0060330	regulation of response to interferon-gamma

0.71	GO:0051082	unfolded protein binding
0.55	GO:0043008	ATP-dependent protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:1990226	histone methyltransferase binding
0.54	GO:0070182	DNA polymerase binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0097718	disordered domain specific binding
0.52	GO:0042826	histone deacetylase binding

0.55	GO:0034751	aryl hydrocarbon receptor complex
0.50	GO:0008180	COP9 signalosome
0.46	GO:0005576	extracellular region
0.46	GO:0005829	cytosol
0.43	GO:0042470	melanosome
0.42	GO:1990917	ooplasm
0.42	GO:1990913	sperm head plasma membrane
0.41	GO:0005739	mitochondrion
0.40	GO:0031526	brush border membrane
0.40	GO:0016234	inclusion body

sp|P34064|PSA5_RAT
Proteasome subunit alpha type-5
Search

PSMA5

0.48	Proteasome endopeptidase complex

0.76	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0045595	regulation of cell differentiation
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0051005	negative regulation of lipoprotein lipase activity
0.35	GO:0071310	cellular response to organic substance

0.77	GO:0004298	threonine-type endopeptidase activity
0.35	GO:0030379	neurotensin receptor activity, non-G-protein coupled
0.35	GO:0010465	nerve growth factor receptor activity
0.35	GO:0048406	nerve growth factor binding
0.33	GO:0019899	enzyme binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.58	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.35	GO:0012505	endomembrane system
0.35	GO:0031983	vesicle lumen
0.35	GO:0097708	intracellular vesicle
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0098589	membrane region

0.77

GO:0004298

sp|P34067|PSB4_RAT
Proteasome subunit beta type-4
Search

PSMB4

0.57	Proteasome subunit beta

0.71	GO:0051603	proteolysis involved in cellular protein catabolic process
0.59	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.55	GO:0001530	lipopolysaccharide binding
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.75	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

sp|P34080|AQP2_RAT
Aquaporin-2
Search

AQP2

0.95	Aquaporin-2

0.60	GO:0071288	cellular response to mercury ion
0.59	GO:0071280	cellular response to copper ion
0.59	GO:0015793	glycerol transport
0.58	GO:0072205	metanephric collecting duct development
0.58	GO:0003097	renal water transport
0.57	GO:0042631	cellular response to water deprivation
0.55	GO:0055085	transmembrane transport
0.38	GO:0006811	ion transport
0.36	GO:0033762	response to glucagon
0.36	GO:0010226	response to lithium ion

0.69	GO:0022803	passive transmembrane transporter activity
0.59	GO:0015168	glycerol transmembrane transporter activity
0.57	GO:0005372	water transmembrane transporter activity
0.35	GO:0030165	PDZ domain binding
0.34	GO:0003779	actin binding
0.34	GO:0042802	identical protein binding

0.57	GO:0016324	apical plasma membrane
0.54	GO:0055037	recycling endosome
0.54	GO:0070062	extracellular exosome
0.44	GO:0016323	basolateral plasma membrane
0.42	GO:0030659	cytoplasmic vesicle membrane
0.41	GO:0005794	Golgi apparatus
0.40	GO:0005887	integral component of plasma membrane
0.36	GO:0046930	pore complex
0.36	GO:0030133	transport vesicle
0.36	GO:0031303	integral component of endosome membrane

sp|P34131|NTF4_RAT
Neurotrophin-4
Search

NTF3

0.61	Neurotrophin-4

0.75	GO:0010469	regulation of receptor activity
0.56	GO:0061193	taste bud development
0.56	GO:0007402	ganglion mother cell fate determination
0.54	GO:0008052	sensory organ boundary specification
0.53	GO:0060384	innervation
0.52	GO:0007616	long-term memory
0.52	GO:0042490	mechanoreceptor differentiation
0.52	GO:0008344	adult locomotory behavior
0.51	GO:0008544	epidermis development
0.50	GO:0060548	negative regulation of cell death

0.78	GO:0008083	growth factor activity
0.68	GO:0005165	neurotrophin receptor binding
0.44	GO:0008191	metalloendopeptidase inhibitor activity
0.42	GO:0090729	toxin activity

0.55	GO:0005576	extracellular region
0.43	GO:0031410	cytoplasmic vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P34158|CFTR_RAT
Cystic fibrosis transmembrane conductance regulator
Search

CFTR

0.93	Cystic fibrosis transmembrane conductance regulator

0.76	GO:1902476	chloride transmembrane transport
0.71	GO:0035377	transepithelial water transport
0.70	GO:0060081	membrane hyperpolarization
0.69	GO:0045852	pH elevation
0.69	GO:1904322	cellular response to forskolin
0.68	GO:0048240	sperm capacitation
0.68	GO:0015701	bicarbonate transport
0.67	GO:0071320	cellular response to cAMP
0.66	GO:0050891	multicellular organismal water homeostasis
0.65	GO:0051453	regulation of intracellular pH

0.86	GO:0005260	intracellularly ATP-gated chloride channel activity
0.68	GO:0019869	chloride channel inhibitor activity
0.68	GO:0015106	bicarbonate transmembrane transporter activity
0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.54	GO:0030165	PDZ domain binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.48	GO:0019899	enzyme binding

0.81	GO:0034707	chloride channel complex
0.64	GO:0016324	apical plasma membrane
0.64	GO:0055037	recycling endosome
0.62	GO:0005769	early endosome
0.57	GO:0005789	endoplasmic reticulum membrane
0.56	GO:0098588	bounding membrane of organelle
0.55	GO:0044440	endosomal part
0.54	GO:0005887	integral component of plasma membrane
0.53	GO:0005791	rough endoplasmic reticulum
0.52	GO:0098805	whole membrane

0.86

EC:3.6.3.49

GO:0005260

sp|P34207|PR3D4_RAT
Prolactin-3D4
Search

0.74	Placental lactogen I mosaic

0.76	GO:0010469	regulation of receptor activity
0.51	GO:0046427	positive regulation of JAK-STAT cascade
0.50	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.50	GO:0001937	negative regulation of endothelial cell proliferation
0.49	GO:0040014	regulation of multicellular organism growth
0.40	GO:0007595	lactation
0.39	GO:0001666	response to hypoxia
0.38	GO:0032147	activation of protein kinase activity
0.38	GO:0008284	positive regulation of cell proliferation
0.38	GO:0018108	peptidyl-tyrosine phosphorylation

0.79	GO:0005179	hormone activity
0.44	GO:0005148	prolactin receptor binding

0.66	GO:0005576	extracellular region
0.36	GO:0031904	endosome lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P34900|SDC2_RAT
Syndecan-2
Search

SDC2

0.82

Syndecan

0.55	GO:0048814	regulation of dendrite morphogenesis
0.48	GO:0016477	cell migration
0.47	GO:0048813	dendrite morphogenesis
0.42	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.42	GO:0070121	Kupffer's vesicle development
0.41	GO:0002040	sprouting angiogenesis
0.41	GO:0048565	digestive tract development
0.40	GO:0007507	heart development
0.39	GO:0097435	supramolecular fiber organization
0.37	GO:0042060	wound healing

0.57	GO:0030165	PDZ domain binding
0.51	GO:0042802	identical protein binding
0.34	GO:0070053	thrombospondin receptor activity
0.33	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.52	GO:0031012	extracellular matrix
0.45	GO:0009986	cell surface
0.38	GO:0005796	Golgi lumen
0.36	GO:0043202	lysosomal lumen
0.35	GO:0043025	neuronal cell body
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0045202	synapse
0.34	GO:0005886	plasma membrane
0.33	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

sp|P34901|SDC4_RAT
Syndecan-4
Search

SDC4

0.80

Syndecan

0.59	GO:1903553	positive regulation of extracellular exosome assembly
0.58	GO:1903543	positive regulation of exosomal secretion
0.58	GO:0042060	wound healing
0.57	GO:0010762	regulation of fibroblast migration
0.57	GO:0002009	morphogenesis of an epithelium
0.57	GO:0060122	inner ear receptor cell stereocilium organization
0.57	GO:0042130	negative regulation of T cell proliferation
0.56	GO:0060606	tube closure
0.55	GO:0021915	neural tube development
0.54	GO:0048598	embryonic morphogenesis

0.60	GO:0070053	thrombospondin receptor activity
0.53	GO:0042802	identical protein binding
0.42	GO:0030165	PDZ domain binding
0.41	GO:0005080	protein kinase C binding
0.40	GO:0001968	fibronectin binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.35	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0046983	protein dimerization activity
0.33	GO:0030554	adenyl nucleotide binding

0.53	GO:0009986	cell surface
0.41	GO:0005925	focal adhesion
0.40	GO:0005576	extracellular region
0.40	GO:0043034	costamere
0.39	GO:0098857	membrane microdomain
0.38	GO:0005796	Golgi lumen
0.36	GO:0043202	lysosomal lumen
0.35	GO:0031982	vesicle
0.35	GO:0005886	plasma membrane
0.33	GO:0005788	endoplasmic reticulum lumen

0.35

GO:0004714

sp|P34926|MAP1A_RAT
Microtubule-associated protein 1A
Search

MAP1A

0.86	Microtubule-associated protein 1A

0.76	GO:0000226	microtubule cytoskeleton organization
0.46	GO:0045494	photoreceptor cell maintenance
0.45	GO:0007605	sensory perception of sound
0.42	GO:0007026	negative regulation of microtubule depolymerization

0.74	GO:0008017	microtubule binding
0.41	GO:0005518	collagen binding
0.39	GO:0003779	actin binding
0.34	GO:0005198	structural molecule activity

0.73	GO:0005874	microtubule
0.46	GO:0001750	photoreceptor outer segment
0.45	GO:0014069	postsynaptic density
0.41	GO:0005875	microtubule associated complex
0.41	GO:0005829	cytosol
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon

sp|P34975|OPRK_RAT
Kappa-type opioid receptor
Search

OPRK1

0.97	Kappa-type opioid receptor

0.85	GO:0038003	opioid receptor signaling pathway
0.57	GO:0019233	sensory perception of pain
0.57	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.57	GO:0046877	regulation of saliva secretion
0.52	GO:0051607	defense response to virus
0.52	GO:0007626	locomotory behavior
0.51	GO:0007218	neuropeptide signaling pathway
0.51	GO:0006955	immune response
0.46	GO:0007268	chemical synaptic transmission
0.43	GO:0043278	response to morphine

0.85	GO:0004985	opioid receptor activity
0.50	GO:0042923	neuropeptide binding
0.43	GO:0004977	melanocortin receptor activity
0.43	GO:0008188	neuropeptide receptor activity
0.43	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.36	GO:0005515	protein binding
0.34	GO:0005245	voltage-gated calcium channel activity

0.49	GO:0005887	integral component of plasma membrane
0.48	GO:0005829	cytosol
0.47	GO:0043005	neuron projection
0.45	GO:0005634	nucleus
0.41	GO:0043204	perikaryon
0.39	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0098793	presynapse
0.36	GO:0045203	integral component of cell outer membrane
0.33	GO:0005768	endosome

sp|P34978|TA2R_RAT
Thromboxane A2 receptor
Search

TBXA2R

0.97	Thromboxane A2 receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.59	GO:0032496	response to lipopolysaccharide
0.59	GO:0019229	regulation of vasoconstriction
0.58	GO:0045987	positive regulation of smooth muscle contraction
0.57	GO:0019932	second-messenger-mediated signaling
0.55	GO:0006954	inflammatory response
0.49	GO:0045777	positive regulation of blood pressure
0.48	GO:1903524	positive regulation of blood circulation
0.47	GO:0071799	cellular response to prostaglandin D stimulus

0.85	GO:0004954	prostanoid receptor activity
0.35	GO:0005515	protein binding
0.34	GO:0098772	molecular function regulator

0.55	GO:0016607	nuclear speck
0.45	GO:0005886	plasma membrane
0.42	GO:0001669	acrosomal vesicle
0.40	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P34980|PE2R3_RAT
Prostaglandin E2 receptor EP3 subtype
Search

PTGER3

0.97	Prostaglandin E receptor 3

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0060455	negative regulation of gastric acid secretion
0.52	GO:0014827	intestine smooth muscle contraction
0.41	GO:0031622	positive regulation of fever generation
0.39	GO:0035810	positive regulation of urine volume
0.39	GO:0001660	fever generation
0.38	GO:0015701	bicarbonate transport
0.38	GO:0032496	response to lipopolysaccharide
0.38	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.38	GO:1990767	prostaglandin receptor internalization

0.85	GO:0004957	prostaglandin E receptor activity
0.49	GO:0004960	thromboxane receptor activity
0.35	GO:0005515	protein binding
0.33	GO:0004958	prostaglandin F receptor activity
0.32	GO:0046872	metal ion binding

0.37	GO:1990769	proximal neuron projection
0.36	GO:0005635	nuclear envelope
0.36	GO:0005886	plasma membrane
0.36	GO:0005903	brush border
0.35	GO:0043025	neuronal cell body
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0009986	cell surface
0.33	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|P34987|OL867_RAT
Olfactory receptor 867
Search

0.44	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P34997|CXCR5_RAT
C-X-C chemokine receptor type 5
Search

CXCR5

0.92	C-X-C motif chemokine receptor 5

0.81	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.69	GO:0006935	chemotaxis
0.69	GO:0048535	lymph node development
0.65	GO:0042113	B cell activation
0.65	GO:0006955	immune response
0.58	GO:0006954	inflammatory response
0.54	GO:0032467	positive regulation of cytokinesis
0.54	GO:0016477	cell migration
0.47	GO:0090026	positive regulation of monocyte chemotaxis

0.82	GO:0004950	chemokine receptor activity
0.49	GO:0019956	chemokine binding
0.41	GO:0004983	neuropeptide Y receptor activity
0.39	GO:0004435	phosphatidylinositol phospholipase C activity
0.38	GO:0004982	N-formyl peptide receptor activity
0.35	GO:0004875	complement receptor activity
0.34	GO:0003779	actin binding
0.33	GO:0004535	poly(A)-specific ribonuclease activity
0.33	GO:0005124	scavenger receptor binding
0.33	GO:0005044	scavenger receptor activity

0.57	GO:0009897	external side of plasma membrane
0.37	GO:0043025	neuronal cell body
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0005768	endosome
0.33	GO:0101003	ficolin-1-rich granule membrane
0.33	GO:0035577	azurophil granule membrane
0.32	GO:0005615	extracellular space
0.32	GO:0005739	mitochondrion

0.39	EC:3.1.4.11	GO:0004435
0.39	KEGG:R03435	GO:0004435

sp|P35000|VIPR2_RAT
Vasoactive intestinal polypeptide receptor 2
Search

VIPR2

0.95	Vasoactive intestinal polypeptide receptor

0.68	GO:0007166	cell surface receptor signaling pathway
0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0007190	activation of adenylate cyclase activity
0.41	GO:0048662	negative regulation of smooth muscle cell proliferation
0.34	GO:0007267	cell-cell signaling

0.84

GO:0004999

vasoactive intestinal polypeptide receptor activity

0.50	GO:0005886	plasma membrane
0.36	GO:0043235	receptor complex
0.35	GO:0005929	cilium
0.30	GO:0044425	membrane part

sp|P35053|GPC1_RAT
Glypican-1
Search

GPC1

0.97	Glypican-1 isoform B

0.70	GO:0009966	regulation of signal transduction
0.63	GO:2001016	positive regulation of skeletal muscle cell differentiation
0.58	GO:0030200	heparan sulfate proteoglycan catabolic process
0.54	GO:1902724	positive regulation of skeletal muscle satellite cell proliferation
0.52	GO:1902723	negative regulation of skeletal muscle satellite cell proliferation
0.52	GO:1902725	negative regulation of satellite cell differentiation
0.52	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.48	GO:0023057	negative regulation of signaling
0.48	GO:0010648	negative regulation of cell communication
0.40	GO:0032288	myelin assembly

0.85	GO:0043395	heparan sulfate proteoglycan binding
0.54	GO:0017134	fibroblast growth factor binding
0.54	GO:0043236	laminin binding
0.48	GO:0005507	copper ion binding
0.37	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.37	GO:0070052	collagen V binding
0.35	GO:0033549	MAP kinase phosphatase activity

0.83	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix
0.52	GO:0045121	membrane raft
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.41	GO:0005615	extracellular space
0.39	GO:0005768	endosome
0.39	GO:0005796	Golgi lumen
0.37	GO:1903561	extracellular vesicle
0.36	GO:0043202	lysosomal lumen

0.37

EC:3.1.3

GO:0008138

sp|P35171|CX7A2_RAT
Cytochrome c oxidase subunit 7A2, mitochondrial
Search

COX7A2

0.97	Cytochrome c oxidase polypeptide VIIa-liver/heart, mitochondrial

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity

0.78	GO:0005746	mitochondrial respiratory chain
0.38	GO:0070062	extracellular exosome
0.34	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9

GO:0016675

sp|P35213|1433B_RAT
14-3-3 protein beta/alpha
Search

YWHAB

0.96	14-3-3 protein beta/alpha

0.51	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.49	GO:0051220	cytoplasmic sequestering of protein
0.48	GO:0035308	negative regulation of protein dephosphorylation
0.45	GO:0006605	protein targeting
0.44	GO:0043085	positive regulation of catalytic activity
0.39	GO:0090168	Golgi reassembly
0.39	GO:0051683	establishment of Golgi localization
0.39	GO:0051291	protein heterooligomerization
0.38	GO:0010941	regulation of cell death
0.37	GO:0045892	negative regulation of transcription, DNA-templated

0.73	GO:0019904	protein domain specific binding
0.50	GO:0050815	phosphoserine residue binding
0.49	GO:0045296	cadherin binding
0.48	GO:0042826	histone deacetylase binding
0.46	GO:0042802	identical protein binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0044325	ion channel binding
0.38	GO:0003714	transcription corepressor activity
0.38	GO:0032403	protein complex binding
0.37	GO:0031625	ubiquitin protein ligase binding

0.47	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0042470	melanosome
0.43	GO:0005829	cytosol
0.38	GO:0017053	transcriptional repressor complex
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.36	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0005739	mitochondrion
0.35	GO:0043234	protein complex

sp|P35231|REG3A_RAT
Regenerating islet-derived protein 3-alpha
Search

0.97	Regenerating islet-derived protein 3-alpha

0.75	GO:0045617	negative regulation of keratinocyte differentiation
0.75	GO:0010838	positive regulation of keratinocyte proliferation
0.71	GO:0090303	positive regulation of wound healing
0.69	GO:0044278	cell wall disruption in other organism
0.68	GO:0006953	acute-phase response
0.66	GO:0050830	defense response to Gram-positive bacterium
0.65	GO:0019730	antimicrobial humoral response
0.63	GO:0050829	defense response to Gram-negative bacterium
0.61	GO:0051715	cytolysis in other organism
0.57	GO:0002755	MyD88-dependent toll-like receptor signaling pathway

0.64	GO:0070492	oligosaccharide binding
0.58	GO:0042834	peptidoglycan binding
0.55	GO:0042802	identical protein binding
0.42	GO:0019838	growth factor binding

0.56	GO:0030141	secretory granule
0.54	GO:0005576	extracellular region
0.45	GO:0044217	other organism part
0.41	GO:0045177	apical part of cell
0.37	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P35233|PTN2_RAT
Tyrosine-protein phosphatase non-receptor type 2
Search

PTPN2

0.74	Tyrosine-protein phosphatase non-receptor type

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.56	GO:1902206	negative regulation of interleukin-2-mediated signaling pathway
0.56	GO:1902215	negative regulation of interleukin-4-mediated signaling pathway
0.56	GO:1902233	negative regulation of positive thymic T cell selection
0.56	GO:0070104	negative regulation of interleukin-6-mediated signaling pathway
0.55	GO:1902227	negative regulation of macrophage colony-stimulating factor signaling pathway
0.55	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway
0.54	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway
0.54	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.54	GO:0060331	negative regulation of response to interferon-gamma

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0097677	STAT family protein binding
0.52	GO:0030971	receptor tyrosine kinase binding
0.51	GO:0005178	integrin binding
0.50	GO:0019905	syntaxin binding
0.34	GO:0046875	ephrin receptor binding
0.34	GO:0045296	cadherin binding
0.33	GO:0003677	DNA binding
0.33	GO:0008270	zinc ion binding

0.51	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.46	GO:0005654	nucleoplasm
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.35	GO:0031965	nuclear membrane
0.34	GO:0097443	sorting endosome
0.34	GO:0005769	early endosome
0.33	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.75

GO:0004725

sp|P35234|PTN5_RAT
Tyrosine-protein phosphatase non-receptor type 5
Search

PTPN5

0.97	Tyrosine-protein phosphatase non-receptor type 5

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.46	GO:0038128	ERBB2 signaling pathway
0.45	GO:0010633	negative regulation of epithelial cell migration
0.44	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.44	GO:0001701	in utero embryonic development
0.36	GO:1903492	response to acetylsalicylate
0.35	GO:0035902	response to immobilization stress
0.35	GO:1900273	positive regulation of long-term synaptic potentiation
0.35	GO:0033160	positive regulation of protein import into nucleus, translocation
0.35	GO:0001975	response to amphetamine

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0001784	phosphotyrosine residue binding
0.43	GO:0019901	protein kinase binding
0.35	GO:0035254	glutamate receptor binding
0.34	GO:0019198	transmembrane receptor protein phosphatase activity

0.42	GO:0030054	cell junction
0.41	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:1990635	proximal dendrite
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0043204	perikaryon
0.35	GO:0031984	organelle subcompartment
0.34	GO:0030424	axon
0.34	GO:0005654	nucleoplasm

0.75

GO:0004725

sp|P35248|SFTPD_RAT
Pulmonary surfactant-associated protein D
Search

SFTPD

0.97	Pulmonary surfactant-associated protein D

0.66	GO:1905226	regulation of adhesion of symbiont to host epithelial cell
0.65	GO:0043129	surfactant homeostasis
0.64	GO:0043152	induction of bacterial agglutination
0.64	GO:0052405	negative regulation by host of symbiont molecular function
0.63	GO:0048286	lung alveolus development
0.48	GO:0007585	respiratory gaseous exchange
0.45	GO:0045087	innate immune response
0.41	GO:0032703	negative regulation of interleukin-2 production
0.41	GO:0050766	positive regulation of phagocytosis
0.41	GO:0042130	negative regulation of T cell proliferation

0.45	GO:0042802	identical protein binding
0.44	GO:0030246	carbohydrate binding
0.43	GO:0005201	extracellular matrix structural constituent
0.38	GO:0001530	lipopolysaccharide binding
0.35	GO:0036094	small molecule binding
0.34	GO:0005178	integrin binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.32	GO:0004713	protein tyrosine kinase activity
0.32	GO:0005509	calcium ion binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005581	collagen trimer
0.47	GO:0031012	extracellular matrix
0.43	GO:0005615	extracellular space
0.38	GO:0005771	multivesicular body
0.38	GO:0005783	endoplasmic reticulum
0.38	GO:0042599	lamellar body
0.37	GO:0045334	clathrin-coated endocytic vesicle
0.36	GO:0005764	lysosome
0.36	GO:0019867	outer membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.32

GO:0004713

sp|P35280|RAB8A_RAT
Ras-related protein Rab-8A
Search

RAB8A

0.92	Oncogene c-mel

0.57	GO:0048210	Golgi vesicle fusion to target membrane
0.54	GO:0006904	vesicle docking involved in exocytosis
0.52	GO:0060271	cilium assembly
0.50	GO:0010506	regulation of autophagy
0.50	GO:0072659	protein localization to plasma membrane
0.48	GO:0017157	regulation of exocytosis
0.45	GO:0048666	neuron development
0.44	GO:0009306	protein secretion
0.43	GO:0032402	melanosome transport
0.43	GO:0032869	cellular response to insulin stimulus

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.56	GO:0031489	myosin V binding
0.55	GO:0019003	GDP binding
0.40	GO:0017137	Rab GTPase binding
0.38	GO:0019901	protein kinase binding
0.36	GO:0071532	ankyrin repeat binding
0.36	GO:0032794	GTPase activating protein binding
0.35	GO:0030911	TPR domain binding
0.35	GO:0005102	receptor binding

0.56	GO:0055038	recycling endosome membrane
0.54	GO:0045335	phagocytic vesicle
0.54	GO:0097546	ciliary base
0.53	GO:0097730	non-motile cilium
0.53	GO:0030133	transport vesicle
0.52	GO:0036064	ciliary basal body
0.51	GO:0005813	centrosome
0.50	GO:0030136	clathrin-coated vesicle
0.49	GO:0005798	Golgi-associated vesicle
0.48	GO:0030667	secretory granule membrane

sp|P35281|RAB10_RAT
Ras-related protein Rab-10
Search

RAB10

0.83	Putative rab subfamily protein of small gtpase

0.59	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane
0.57	GO:0071786	endoplasmic reticulum tubular network organization
0.55	GO:0032869	cellular response to insulin stimulus
0.53	GO:0016197	endosomal transport
0.52	GO:0072659	protein localization to plasma membrane
0.51	GO:0098609	cell-cell adhesion
0.51	GO:0019882	antigen processing and presentation
0.48	GO:0016192	vesicle-mediated transport
0.47	GO:0017157	regulation of exocytosis
0.46	GO:0061564	axon development

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.57	GO:0098641	cadherin binding involved in cell-cell adhesion
0.57	GO:0031489	myosin V binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0051021	GDP-dissociation inhibitor binding

0.61	GO:0032593	insulin-responsive compartment
0.56	GO:0071782	endoplasmic reticulum tubular network
0.55	GO:0055037	recycling endosome
0.54	GO:0005913	cell-cell adherens junction
0.53	GO:0070382	exocytic vesicle
0.52	GO:0005929	cilium
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0005886	plasma membrane
0.42	GO:0030670	phagocytic vesicle membrane

sp|P35284|RAB12_RAT
Ras-related protein Rab-12
Search

RAB12

0.96	RAB12, member RAS oncogene family

0.55	GO:0008333	endosome to lysosome transport
0.54	GO:0071346	cellular response to interferon-gamma
0.54	GO:0016239	positive regulation of macroautophagy
0.48	GO:0044257	cellular protein catabolic process
0.39	GO:0006914	autophagy
0.37	GO:0015031	protein transport
0.33	GO:0032869	cellular response to insulin stimulus
0.33	GO:0017157	regulation of exocytosis
0.33	GO:0006904	vesicle docking involved in exocytosis
0.33	GO:0002790	peptide secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.55	GO:0055038	recycling endosome membrane
0.53	GO:0005776	autophagosome
0.53	GO:0045335	phagocytic vesicle
0.51	GO:0005764	lysosome
0.44	GO:0005794	Golgi apparatus
0.39	GO:0098852	lytic vacuole membrane
0.37	GO:0031984	organelle subcompartment
0.36	GO:0030141	secretory granule
0.34	GO:0005829	cytosol
0.33	GO:0005769	early endosome

sp|P35286|RAB13_RAT
Ras-related protein Rab-13
Search

RAB13

0.81	LOW QUALITY PROTEIN: ras-related protein Rab-13

0.57	GO:1902463	protein localization to cell leading edge
0.55	GO:0010737	protein kinase A signaling
0.55	GO:0035767	endothelial cell chemotaxis
0.54	GO:0070830	bicellular tight junction assembly
0.53	GO:0072659	protein localization to plasma membrane
0.53	GO:0032456	endocytic recycling
0.50	GO:0031175	neuron projection development
0.45	GO:0044795	trans-Golgi network to recycling endosome transport
0.45	GO:0061865	polarized secretion of basement membrane proteins in epithelium
0.43	GO:0003006	developmental process involved in reproduction

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.39	GO:0071532	ankyrin repeat binding
0.39	GO:0034236	protein kinase A catalytic subunit binding
0.38	GO:0032794	GTPase activating protein binding

0.56	GO:0055037	recycling endosome
0.53	GO:0016328	lateral plasma membrane
0.52	GO:0097458	neuron part
0.52	GO:0030027	lamellipodium
0.51	GO:0030139	endocytic vesicle
0.51	GO:0005923	bicellular tight junction
0.51	GO:0005802	trans-Golgi network
0.45	GO:0005829	cytosol
0.43	GO:0032593	insulin-responsive compartment
0.42	GO:0010008	endosome membrane

sp|P35289|RAB15_RAT
Ras-related protein Rab-15
Search

RAB15

0.92	Putative rab subfamily protein of small gtpase

0.54	GO:0017157	regulation of exocytosis
0.49	GO:1903532	positive regulation of secretion by cell
0.48	GO:0006904	vesicle docking involved in exocytosis
0.46	GO:0045046	protein import into peroxisome membrane
0.44	GO:0009306	protein secretion
0.43	GO:0019882	antigen processing and presentation
0.40	GO:0072659	protein localization to plasma membrane
0.37	GO:0009653	anatomical structure morphogenesis
0.37	GO:0051459	regulation of corticotropin secretion
0.37	GO:0006979	response to oxidative stress

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.45	GO:0019003	GDP binding
0.42	GO:0005102	receptor binding
0.38	GO:0004602	glutathione peroxidase activity
0.37	GO:0030911	TPR domain binding
0.34	GO:0071532	ankyrin repeat binding
0.34	GO:0032794	GTPase activating protein binding
0.32	GO:0046983	protein dimerization activity
0.31	GO:0016740	transferase activity

0.50	GO:0031410	cytoplasmic vesicle
0.49	GO:0098805	whole membrane
0.49	GO:0098588	bounding membrane of organelle
0.49	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005929	cilium
0.45	GO:0012505	endomembrane system
0.43	GO:0044438	microbody part
0.43	GO:0016604	nuclear body
0.43	GO:0005777	peroxisome
0.40	GO:0098793	presynapse

0.38

EC:1.11.1.9

GO:0004602

sp|P35332|HPCL4_RAT
Hippocalcin-like protein 4
Search

HPCAL4

0.97	Hippocalcin like 4

0.54	GO:0065009	regulation of molecular function
0.50	GO:0007165	signal transduction
0.47	GO:0046676	negative regulation of insulin secretion
0.47	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.46	GO:0045921	positive regulation of exocytosis
0.34	GO:0007417	central nervous system development

0.70	GO:0005509	calcium ion binding
0.66	GO:0005246	calcium channel regulator activity
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.42	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P35345|MC5R_RAT
Melanocortin receptor 5
Search

MC5R

0.97	Melanocortin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0019933	cAMP-mediated signaling
0.41	GO:0030819	positive regulation of cAMP biosynthetic process
0.40	GO:2000252	negative regulation of feeding behavior
0.40	GO:0097009	energy homeostasis
0.38	GO:0040008	regulation of growth
0.38	GO:0006112	energy reserve metabolic process

0.84	GO:0004977	melanocortin receptor activity
0.39	GO:0042562	hormone binding
0.33	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.36	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P35349|GRM6_RAT
Metabotropic glutamate receptor 6
Search

0.76	Metabotropic glutamate receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0050908	detection of light stimulus involved in visual perception
0.59	GO:0007215	glutamate receptor signaling pathway
0.57	GO:0090280	positive regulation of calcium ion import
0.54	GO:0051966	regulation of synaptic transmission, glutamatergic
0.51	GO:0060041	retina development in camera-type eye
0.50	GO:0007626	locomotory behavior
0.40	GO:0007268	chemical synaptic transmission
0.36	GO:0050954	sensory perception of mechanical stimulus
0.35	GO:0019220	regulation of phosphate metabolic process

0.71	GO:0004930	G-protein coupled receptor activity
0.59	GO:0008066	glutamate receptor activity
0.50	GO:0042803	protein homodimerization activity
0.35	GO:0010855	adenylate cyclase inhibitor activity
0.35	GO:0070905	serine binding

0.55	GO:0005886	plasma membrane
0.54	GO:0035841	new growing cell tip
0.50	GO:0098793	presynapse
0.50	GO:0000139	Golgi membrane
0.49	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0036477	somatodendritic compartment
0.40	GO:0043005	neuron projection
0.39	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0098794	postsynapse
0.34	GO:0044297	cell body

sp|P35351|AGTR2_RAT
Type-2 angiotensin II receptor
Search

AGTR2

0.97	Type-2 angiotensin II receptor

0.78	GO:0038166	angiotensin-activated signaling pathway
0.74	GO:0097746	regulation of blood vessel diameter
0.71	GO:0006954	inflammatory response
0.67	GO:0042981	regulation of apoptotic process
0.66	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway
0.64	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.61	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
0.61	GO:0035566	regulation of metanephros size
0.61	GO:0002035	brain renin-angiotensin system
0.61	GO:0003072	renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure

0.81	GO:0004945	angiotensin type II receptor activity
0.49	GO:0019956	chemokine binding
0.47	GO:0004950	chemokine receptor activity
0.45	GO:0005044	scavenger receptor activity
0.42	GO:0015026	coreceptor activity
0.40	GO:0017046	peptide hormone binding
0.38	GO:0016520	growth hormone-releasing hormone receptor activity
0.38	GO:0008134	transcription factor binding
0.36	GO:0001965	G-protein alpha-subunit binding
0.36	GO:0048019	receptor antagonist activity

0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005886	plasma membrane
0.37	GO:0005768	endosome
0.35	GO:0005905	clathrin-coated pit
0.35	GO:0009986	cell surface
0.35	GO:0043005	neuron projection
0.34	GO:0005576	extracellular region
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.35

EC:2.7.11.14

GO:0050254

sp|P35353|CRFR1_RAT
Corticotropin-releasing factor receptor 1
Search

CRHR1

0.95	Corticotrophin-releasing factor type 1 alpha receptor

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0051458	corticotropin secretion
0.49	GO:2000852	regulation of corticosterone secretion
0.49	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.46	GO:0019933	cAMP-mediated signaling
0.45	GO:0051867	general adaptation syndrome, behavioral process
0.43	GO:0030325	adrenal gland development
0.43	GO:0042596	fear response
0.43	GO:0048149	behavioral response to ethanol

0.72	GO:0004930	G-protein coupled receptor activity
0.41	GO:0043404	corticotropin-releasing hormone receptor activity
0.40	GO:0051424	corticotropin-releasing hormone binding
0.40	GO:0001965	G-protein alpha-subunit binding
0.38	GO:0032403	protein complex binding

0.48	GO:0005886	plasma membrane
0.40	GO:0005768	endosome
0.39	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0045177	apical part of cell
0.38	GO:0005802	trans-Golgi network
0.37	GO:0044309	neuron spine
0.36	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

sp|P35355|PGH2_RAT
Prostaglandin G/H synthase 2
Search

PTGS2

0.96	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase)

0.86	GO:0019371	cyclooxygenase pathway
0.83	GO:0008217	regulation of blood pressure
0.80	GO:0006954	inflammatory response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.59	GO:0071471	cellular response to non-ionic osmotic stress
0.59	GO:0031394	positive regulation of prostaglandin biosynthetic process
0.58	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.57	GO:0031622	positive regulation of fever generation
0.57	GO:0090336	positive regulation of brown fat cell differentiation

0.86	GO:0004666	prostaglandin-endoperoxide synthase activity
0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0019899	enzyme binding
0.40	GO:0051213	dioxygenase activity
0.36	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
0.36	GO:0046872	metal ion binding

0.52	GO:0043005	neuron projection
0.50	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.38	GO:0031090	organelle membrane
0.38	GO:0005901	caveola
0.34	GO:0043234	protein complex
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

0.86	EC:1.14.99.1	GO:0004666
0.72	KEGG:R03532	GO:0004601

sp|P35364|5HT5A_RAT
5-hydroxytryptamine receptor 5A
Search

HTR5A

0.97	5-hydroxytryptamine (Serotonin) receptor 5A, G protein-coupled

0.83	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.58	GO:0019933	cAMP-mediated signaling
0.49	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.41	GO:0032355	response to estradiol
0.41	GO:0021766	hippocampus development

0.83	GO:0099589	serotonin receptor activity
0.80	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.80	GO:0008227	G-protein coupled amine receptor activity
0.51	GO:0051378	serotonin binding
0.33	GO:0008144	drug binding

0.62	GO:0005887	integral component of plasma membrane
0.41	GO:0043204	perikaryon
0.40	GO:0005791	rough endoplasmic reticulum
0.40	GO:0030425	dendrite
0.38	GO:0005794	Golgi apparatus

sp|P35365|5HT5B_RAT
5-hydroxytryptamine receptor 5B
Search

HTR5A

0.96	5-hydroxytryptamine (Serotonin) receptor 5A, G protein-coupled

0.83	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.56	GO:0019933	cAMP-mediated signaling
0.49	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.40	GO:0032355	response to estradiol
0.40	GO:0021766	hippocampus development

0.83	GO:0099589	serotonin receptor activity
0.80	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.80	GO:0008227	G-protein coupled amine receptor activity
0.51	GO:0051378	serotonin binding
0.34	GO:0008144	drug binding

0.62	GO:0005887	integral component of plasma membrane
0.40	GO:0043204	perikaryon
0.39	GO:0005791	rough endoplasmic reticulum
0.39	GO:0030425	dendrite
0.37	GO:0005794	Golgi apparatus

sp|P35370|OPRX_RAT
Nociceptin receptor
Search

OPRL1

0.97	Nociceptin receptor

0.86	GO:0038003	opioid receptor signaling pathway
0.64	GO:0019233	sensory perception of pain
0.62	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.59	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.49	GO:0007218	neuropeptide signaling pathway
0.48	GO:0007268	chemical synaptic transmission
0.44	GO:0060454	positive regulation of gastric acid secretion
0.44	GO:1904058	positive regulation of sensory perception of pain
0.43	GO:0044849	estrous cycle
0.43	GO:0106072	negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway

0.87	GO:0001626	nociceptin receptor activity
0.52	GO:0042923	neuropeptide binding
0.41	GO:0008022	protein C-terminus binding

0.52	GO:0005887	integral component of plasma membrane
0.47	GO:0043005	neuron projection
0.41	GO:0031410	cytoplasmic vesicle

sp|P35400|GRM7_RAT
Metabotropic glutamate receptor 7
Search

GRM7

0.92	Metabotropic glutamate receptor 7

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0031279	regulation of cyclase activity
0.49	GO:0007605	sensory perception of sound
0.49	GO:0007215	glutamate receptor signaling pathway
0.47	GO:0007268	chemical synaptic transmission
0.45	GO:0051966	regulation of synaptic transmission, glutamatergic
0.41	GO:0001662	behavioral fear response
0.40	GO:0001661	conditioned taste aversion
0.40	GO:0007614	short-term memory
0.39	GO:0019226	transmission of nerve impulse

0.70	GO:0004930	G-protein coupled receptor activity
0.54	GO:0010855	adenylate cyclase inhibitor activity
0.53	GO:0070905	serine binding
0.49	GO:0008066	glutamate receptor activity
0.45	GO:0005246	calcium channel regulator activity
0.41	GO:0016595	glutamate binding
0.39	GO:0030165	PDZ domain binding
0.39	GO:0005245	voltage-gated calcium channel activity
0.37	GO:0005509	calcium ion binding
0.36	GO:0048306	calcium-dependent protein binding

0.53	GO:0005886	plasma membrane
0.49	GO:0030425	dendrite
0.48	GO:0043235	receptor complex
0.47	GO:0005938	cell cortex
0.44	GO:0098793	presynapse
0.37	GO:0032279	asymmetric synapse
0.37	GO:0030424	axon
0.37	GO:0098794	postsynapse
0.36	GO:0044306	neuron projection terminus
0.35	GO:0005791	rough endoplasmic reticulum

sp|P35407|CXCR2_RAT
C-X-C chemokine receptor type 2
Search

0.97	High affinity interleukin-8 receptor B

0.83	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0006935	chemotaxis
0.56	GO:0038112	interleukin-8-mediated signaling pathway
0.52	GO:0031623	receptor internalization
0.49	GO:0006968	cellular defense response
0.49	GO:0002376	immune system process
0.48	GO:0016477	cell migration
0.47	GO:0001775	cell activation
0.46	GO:0006954	inflammatory response

0.85	GO:0016494	C-X-C chemokine receptor activity
0.78	GO:0019959	interleukin-8 binding
0.47	GO:0016493	C-C chemokine receptor activity
0.39	GO:0019957	C-C chemokine binding
0.37	GO:0051916	granulocyte colony-stimulating factor binding
0.35	GO:0031727	CCR2 chemokine receptor binding
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0019960	C-X3-C chemokine binding
0.33	GO:0008289	lipid binding

0.48	GO:0042629	mast cell granule
0.46	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.38	GO:0098552	side of membrane
0.38	GO:0097225	sperm midpiece
0.38	GO:0097228	sperm principal piece
0.36	GO:0030667	secretory granule membrane
0.33	GO:0043025	neuronal cell body
0.33	GO:0005576	extracellular region
0.32	GO:0005654	nucleoplasm

sp|P35411|CX3C1_RAT
CX3C chemokine receptor 1
Search

CX3CR1

0.97	C-X3-C motif chemokine receptor 1

0.84	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0006935	chemotaxis
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0007155	cell adhesion
0.53	GO:0006955	immune response
0.50	GO:0090026	positive regulation of monocyte chemotaxis
0.50	GO:0097529	myeloid leukocyte migration
0.50	GO:0016525	negative regulation of angiogenesis
0.49	GO:0001974	blood vessel remodeling
0.49	GO:0001774	microglial cell activation

0.85	GO:0004950	chemokine receptor activity
0.62	GO:0019956	chemokine binding
0.45	GO:0031727	CCR2 chemokine receptor binding
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0004435	phosphatidylinositol phospholipase C activity

0.50	GO:0005654	nucleoplasm
0.41	GO:0032809	neuronal cell body membrane
0.41	GO:0009897	external side of plasma membrane
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0043005	neuron projection
0.36	GO:0043204	perikaryon
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005829	cytosol

0.33	EC:3.1.4.11	GO:0004435
0.33	KEGG:R03435	GO:0004435

sp|P35426|CDK4_RAT
Cyclin-dependent kinase 4
Search

CDK4

0.80	Cyclin dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.59	GO:0042127	regulation of cell proliferation
0.58	GO:0051726	regulation of cell cycle
0.57	GO:0043697	cell dedifferentiation
0.56	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.55	GO:1904636	response to ionomycin
0.55	GO:0071362	cellular response to ether
0.55	GO:0000082	G1/S transition of mitotic cell cycle
0.53	GO:0071353	cellular response to interleukin-4
0.53	GO:0060612	adipose tissue development

0.67	GO:0004674	protein serine/threonine kinase activity
0.65	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030332	cyclin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.41	GO:0098770	FBXO family protein binding
0.39	GO:0032403	protein complex binding
0.36	GO:0030234	enzyme regulator activity

0.56	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.50	GO:0005923	bicellular tight junction
0.50	GO:0031965	nuclear membrane
0.48	GO:0005667	transcription factor complex
0.47	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.46	GO:0000785	chromatin
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0001726	ruffle
0.38	GO:0005654	nucleoplasm

0.67

GO:0004674

sp|P35427|RL13A_RAT
60S ribosomal protein L13a
Search

RPL13A

0.90	Ribosomal protein 13A, pseudogene 1

0.60	GO:0006518	peptide metabolic process
0.60	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:1901194	negative regulation of formation of translation preinitiation complex
0.44	GO:0071346	cellular response to interferon-gamma
0.39	GO:0010469	regulation of receptor activity
0.39	GO:0048246	macrophage chemotaxis

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0003729	mRNA binding
0.40	GO:0005125	cytokine activity
0.35	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.71	GO:0015934	large ribosomal subunit
0.49	GO:0097452	GAIT complex
0.45	GO:0022626	cytosolic ribosome
0.36	GO:0005925	focal adhesion
0.35	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.35

EC:1.2.1

GO:0016620

sp|P35429|HES2_RAT
Transcription factor HES-2
Search

HES2

0.94	Transcription factor HES-2

0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0006355	regulation of transcription, DNA-templated
0.45	GO:2000974	negative regulation of pro-B cell differentiation
0.45	GO:0050767	regulation of neurogenesis
0.45	GO:0007219	Notch signaling pathway
0.45	GO:0007262	STAT protein import into nucleus
0.45	GO:0051961	negative regulation of nervous system development
0.45	GO:0010721	negative regulation of cell development
0.45	GO:0061106	negative regulation of stomach neuroendocrine cell differentiation
0.44	GO:2000227	negative regulation of pancreatic A cell differentiation

0.68	GO:0046983	protein dimerization activity
0.53	GO:0003677	DNA binding
0.46	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0042826	histone deacetylase binding
0.41	GO:0042802	identical protein binding
0.40	GO:0051087	chaperone binding
0.40	GO:0008134	transcription factor binding
0.35	GO:0008432	JUN kinase binding
0.34	GO:0003682	chromatin binding

0.59	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0005737	cytoplasm
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|P35433|PUR1_RAT
Amidophosphoribosyltransferase
Search

PPAT

0.52	Amidophosphoribosyltransferase

0.73	GO:0009113	purine nucleobase biosynthetic process
0.65	GO:0006189	'de novo' IMP biosynthetic process
0.65	GO:0009116	nucleoside metabolic process
0.40	GO:0007595	lactation
0.40	GO:0031100	animal organ regeneration
0.40	GO:0060135	maternal process involved in female pregnancy
0.40	GO:0051289	protein homotetramerization
0.40	GO:0032869	cellular response to insulin stimulus
0.39	GO:0000082	G1/S transition of mitotic cell cycle
0.39	GO:0006543	glutamine catabolic process

0.77	GO:0004044	amidophosphoribosyltransferase activity
0.61	GO:0051536	iron-sulfur cluster binding
0.52	GO:0046872	metal ion binding

0.35

GO:0005829

cytosol

0.77	EC:2.4.2.14	GO:0004044
0.77	KEGG:R01072	GO:0004044

sp|P35434|ATPD_RAT
ATP synthase subunit delta, mitochondrial
Search

ATP5D

0.45	Mitochondrial ATP synthase subunit delta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0042407	cristae formation
0.35	GO:0046688	response to copper ion
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.33	GO:0006119	oxidative phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.35	GO:0032403	protein complex binding
0.34	GO:0043531	ADP binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.33	GO:0005524	ATP binding
0.32	GO:0003723	RNA binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.54	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005759	mitochondrial matrix

0.34

EC:1.1.1

GO:0016616

sp|P35435|ATPG_RAT
ATP synthase subunit gamma, mitochondrial
Search

ATP5C1

0.72	ATP synthase subunit gamma

0.69	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.69	GO:0006754	ATP biosynthetic process
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0051457	maintenance of protein location in nucleus
0.35	GO:0043433	negative regulation of DNA binding transcription factor activity
0.35	GO:0042407	cristae formation
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0006839	mitochondrial transport
0.33	GO:0046907	intracellular transport

0.70	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.35	GO:0002039	p53 binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0003723	RNA binding

0.71	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.51	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0090575	RNA polymerase II transcription factor complex
0.34	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.30	GO:0016021	integral component of membrane

sp|P35439|NMDZ1_RAT
Glutamate receptor ionotropic, NMDA 1
Search

GRIN1

0.93	Glutamate ionotropic receptor NMDA type subunit 1

0.77	GO:0060079	excitatory postsynaptic potential
0.74	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.54	GO:0018964	propylene metabolic process
0.53	GO:0021586	pons maturation
0.53	GO:0001661	conditioned taste aversion
0.52	GO:1905429	response to glycine
0.52	GO:0060134	prepulse inhibition
0.52	GO:0043278	response to morphine
0.52	GO:0008355	olfactory learning

0.79	GO:0005234	extracellularly glutamate-gated ion channel activity
0.75	GO:0004970	ionotropic glutamate receptor activity
0.53	GO:0016594	glycine binding
0.51	GO:0016595	glutamate binding
0.51	GO:0099094	ligand-gated cation channel activity
0.49	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.49	GO:0022843	voltage-gated cation channel activity
0.49	GO:0005262	calcium channel activity
0.48	GO:0005516	calmodulin binding
0.46	GO:0005102	receptor binding

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.54	GO:0017146	NMDA selective glutamate receptor complex
0.50	GO:0043197	dendritic spine
0.50	GO:0014069	postsynaptic density
0.49	GO:0008021	synaptic vesicle
0.47	GO:0009986	cell surface
0.45	GO:0005783	endoplasmic reticulum
0.40	GO:0044422	organelle part
0.38	GO:0043083	synaptic cleft

sp|P35444|COMP_RAT
Cartilage oligomeric matrix protein
Search

COMP

0.77	Cartilage oligomeric matrix protein variant (Fragment)

0.81	GO:0030198	extracellular matrix organization
0.72	GO:0007155	cell adhesion
0.53	GO:0003417	growth plate cartilage development
0.51	GO:0060173	limb development
0.49	GO:0043066	negative regulation of apoptotic process
0.49	GO:0051451	myoblast migration
0.49	GO:0048266	behavioral response to pain
0.48	GO:0090023	positive regulation of neutrophil chemotaxis
0.48	GO:0034103	regulation of tissue remodeling
0.47	GO:0001938	positive regulation of endothelial cell proliferation

0.70	GO:0005509	calcium ion binding
0.57	GO:0008201	heparin binding
0.53	GO:0043395	heparan sulfate proteoglycan binding
0.53	GO:0032403	protein complex binding
0.52	GO:0002020	protease binding
0.46	GO:0050839	cell adhesion molecule binding
0.43	GO:0005102	receptor binding
0.36	GO:0030545	receptor regulator activity
0.33	GO:0043237	laminin-1 binding
0.33	GO:0001968	fibronectin binding

0.74	GO:0031012	extracellular matrix
0.52	GO:0005615	extracellular space
0.47	GO:0016529	sarcoplasmic reticulum
0.34	GO:1903561	extracellular vesicle
0.33	GO:0031594	neuromuscular junction

sp|P35446|SPON1_RAT
Spondin-1
Search

SPON1

0.70	F-spondin extracellular matrix protein

0.35

GO:0007155

cell adhesion

0.33

GO:0046872

metal ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.43	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|P35465|PAK1_RAT
Serine/threonine-protein kinase PAK 1
Search

PAK1

0.88	LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 1

0.63	GO:0006468	protein phosphorylation
0.58	GO:0060244	negative regulation of cell proliferation involved in contact inhibition
0.57	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.57	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.56	GO:0043406	positive regulation of MAP kinase activity
0.56	GO:0042981	regulation of apoptotic process
0.56	GO:0051496	positive regulation of stress fiber assembly
0.55	GO:0031116	positive regulation of microtubule polymerization
0.55	GO:0043506	regulation of JUN kinase activity
0.55	GO:0033138	positive regulation of peptidyl-serine phosphorylation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0005518	collagen binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0048365	Rac GTPase binding
0.45	GO:0004708	MAP kinase kinase activity
0.39	GO:0042802	identical protein binding
0.37	GO:0019901	protein kinase binding

0.56	GO:0071437	invadopodium
0.54	GO:0001726	ruffle
0.51	GO:0005911	cell-cell junction
0.48	GO:0005829	cytosol
0.43	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.39	GO:0005925	focal adhesion
0.39	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0097447	dendritic tree
0.38	GO:0030424	axon

0.70

GO:0004674

sp|P35467|S10A1_RAT
Protein S100-A1
Search

sp|P35524|CLCN1_RAT
Chloride channel protein 1
Search

CLCN1

0.51	Chloride voltage-gated channel 1

0.77	GO:1902476	chloride transmembrane transport
0.64	GO:0098870	action potential propagation
0.61	GO:0019226	transmission of nerve impulse
0.60	GO:0006936	muscle contraction
0.49	GO:0060689	cell differentiation involved in salivary gland development
0.46	GO:0060041	retina development in camera-type eye
0.42	GO:0034765	regulation of ion transmembrane transport
0.34	GO:0030324	lung development

0.78	GO:0005247	voltage-gated chloride channel activity
0.56	GO:0042803	protein homodimerization activity

0.60	GO:0042383	sarcolemma
0.51	GO:0005887	integral component of plasma membrane
0.43	GO:0034707	chloride channel complex
0.34	GO:0043204	perikaryon
0.34	GO:0030425	dendrite
0.34	GO:0015629	actin cytoskeleton

sp|P35525|CLCN2_RAT
Chloride channel protein 2
Search

CLCN2

0.51	Chloride voltage-gated channel 2

0.76	GO:1902476	chloride transmembrane transport
0.61	GO:0060689	cell differentiation involved in salivary gland development
0.56	GO:0060041	retina development in camera-type eye
0.40	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0030324	lung development
0.34	GO:0010469	regulation of receptor activity

0.78	GO:0005247	voltage-gated chloride channel activity
0.35	GO:0005515	protein binding
0.34	GO:0030545	receptor regulator activity

0.41	GO:0030054	cell junction
0.41	GO:0034707	chloride channel complex
0.36	GO:0043204	perikaryon
0.35	GO:0030425	dendrite
0.35	GO:0005886	plasma membrane
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0005576	extracellular region

sp|P35559|IDE_RAT
Insulin-degrading enzyme
Search

IDE

0.85	Insulin-degrading enzyme

0.60	GO:0006508	proteolysis
0.59	GO:1901143	insulin catabolic process
0.58	GO:0010815	bradykinin catabolic process
0.56	GO:0050435	amyloid-beta metabolic process
0.56	GO:0032461	positive regulation of protein oligomerization
0.56	GO:0010992	ubiquitin recycling
0.54	GO:0008340	determination of adult lifespan
0.51	GO:0051260	protein homooligomerization
0.48	GO:0044257	cellular protein catabolic process
0.47	GO:1990798	pancreas regeneration

0.69	GO:0004222	metalloendopeptidase activity
0.58	GO:0043559	insulin binding
0.57	GO:0140036	ubiquitin-dependent protein binding
0.54	GO:0046872	metal ion binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0005102	receptor binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0031626	beta-endorphin binding

0.50	GO:0005777	peroxisome
0.50	GO:0009986	cell surface
0.49	GO:0005615	extracellular space
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.38	GO:0031907	microbody lumen
0.36	GO:1905369	endopeptidase complex
0.34	GO:0005886	plasma membrane
0.34	GO:0043234	protein complex

0.69

GO:0004222

sp|P35560|KCNJ1_RAT
ATP-sensitive inward rectifier potassium channel 1
Search

KCNJ1

0.97	LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.38	GO:0070294	renal sodium ion absorption
0.37	GO:0043266	regulation of potassium ion transport
0.37	GO:0001894	tissue homeostasis
0.37	GO:0022898	regulation of transmembrane transporter activity
0.37	GO:0001822	kidney development
0.36	GO:0072358	cardiovascular system development

0.84	GO:0005242	inward rectifier potassium channel activity
0.56	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0042277	peptide binding
0.34	GO:0030955	potassium ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005887	integral component of plasma membrane
0.34	GO:0034705	potassium channel complex

sp|P35563|5HT3A_RAT
5-hydroxytryptamine receptor 3A
Search

HTR3A

0.97	5-hydroxytryptamine type 3A receptor

0.59	GO:0007165	signal transduction
0.59	GO:0034220	ion transmembrane transport
0.46	GO:0006812	cation transport
0.41	GO:0042220	response to cocaine
0.40	GO:0045471	response to ethanol
0.40	GO:0032414	positive regulation of ion transmembrane transporter activity
0.39	GO:0071363	cellular response to growth factor stimulus
0.38	GO:0007268	chemical synaptic transmission
0.35	GO:0060078	regulation of postsynaptic membrane potential

0.73	GO:0015276	ligand-gated ion channel activity
0.68	GO:0004888	transmembrane signaling receptor activity
0.59	GO:0051378	serotonin binding
0.54	GO:0022835	transmitter-gated channel activity
0.53	GO:0140135	mechanosensitive cation channel activity
0.37	GO:0042802	identical protein binding
0.35	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

0.76	GO:0045211	postsynaptic membrane
0.61	GO:1904602	serotonin-activated cation-selective channel complex
0.57	GO:0097610	cell surface furrow
0.55	GO:0032155	cell division site part
0.40	GO:0097458	neuron part
0.39	GO:0030054	cell junction
0.39	GO:0044297	cell body
0.38	GO:0120025	plasma membrane bounded cell projection
0.36	GO:0099501	exocytic vesicle membrane
0.35	GO:0031301	integral component of organelle membrane

sp|P35565|CALX_RAT
Calnexin
Search

CANX

0.86	LOW QUALITY PROTEIN: calnexin

0.69	GO:0006457	protein folding
0.56	GO:0048488	synaptic vesicle endocytosis
0.50	GO:0072583	clathrin-dependent endocytosis
0.42	GO:0048916	posterior lateral line development
0.39	GO:0007568	aging
0.36	GO:0070757	interleukin-35-mediated signaling pathway
0.36	GO:0070106	interleukin-27-mediated signaling pathway
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.34	GO:0007339	binding of sperm to zona pellucida

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.40	GO:0034185	apolipoprotein binding
0.40	GO:0035255	ionotropic glutamate receptor binding
0.38	GO:0030246	carbohydrate binding
0.34	GO:0044183	protein binding involved in protein folding
0.34	GO:0003723	RNA binding
0.33	GO:0005198	structural molecule activity

0.70	GO:0005783	endoplasmic reticulum
0.54	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.54	GO:0044233	ER-mitochondrion membrane contact site
0.53	GO:0043209	myelin sheath
0.52	GO:0031984	organelle subcompartment
0.51	GO:0045202	synapse
0.40	GO:0042470	melanosome
0.40	GO:0032839	dendrite cytoplasm
0.39	GO:0044309	neuron spine
0.39	GO:0043025	neuronal cell body

sp|P35570|IRS1_RAT
Insulin receptor substrate 1
Search

IRS1

0.93	Insulin receptor substrate 1

0.85	GO:0048009	insulin-like growth factor receptor signaling pathway
0.85	GO:0032000	positive regulation of fatty acid beta-oxidation
0.85	GO:0045725	positive regulation of glycogen biosynthetic process
0.85	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.84	GO:0046676	negative regulation of insulin secretion
0.84	GO:0008286	insulin receptor signaling pathway
0.83	GO:0014065	phosphatidylinositol 3-kinase signaling
0.50	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.47	GO:0046628	positive regulation of insulin receptor signaling pathway
0.47	GO:0008284	positive regulation of cell proliferation

0.85	GO:0005158	insulin receptor binding
0.85	GO:0043548	phosphatidylinositol 3-kinase binding
0.85	GO:0005159	insulin-like growth factor receptor binding
0.81	GO:0001784	phosphotyrosine residue binding
0.54	GO:0042169	SH2 domain binding
0.53	GO:0004871	signal transducer activity
0.47	GO:0019901	protein kinase binding
0.45	GO:0035591	signaling adaptor activity
0.44	GO:0030674	protein binding, bridging
0.42	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.79	GO:0005901	caveola
0.67	GO:0005829	cytosol
0.60	GO:0005634	nucleus
0.48	GO:0005899	insulin receptor complex
0.45	GO:0036064	ciliary basal body

0.42	EC:2.7.1.153	GO:0046934
0.42	KEGG:R04545	GO:0046934

sp|P35571|GPDM_RAT
Glycerol-3-phosphate dehydrogenase, mitochondrial
Search

GPD2

0.51	Glycerol-3-phosphate dehydrogenase, mitochondrial

0.76	GO:0006072	glycerol-3-phosphate metabolic process
0.53	GO:0035264	multicellular organism growth
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0043010	camera-type eye development
0.48	GO:0019319	hexose biosynthetic process
0.47	GO:0006006	glucose metabolic process
0.40	GO:0019563	glycerol catabolic process
0.37	GO:0006734	NADH metabolic process
0.34	GO:0042180	cellular ketone metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.79	GO:0004368	glycerol-3-phosphate dehydrogenase activity
0.68	GO:0005509	calcium ion binding
0.35	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.76	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:1.1.5.3	GO:0004368
0.35	KEGG:R00842	GO:0004367

sp|P35572|IBP6_RAT
Insulin-like growth factor-binding protein 6
Search

IGFBP6

0.97	Insulin like growth factor binding protein 6

0.78	GO:0001558	regulation of cell growth
0.55	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.40	GO:0008285	negative regulation of cell proliferation
0.39	GO:0044342	type B pancreatic cell proliferation
0.39	GO:0014912	negative regulation of smooth muscle cell migration
0.38	GO:0045663	positive regulation of myoblast differentiation
0.38	GO:0001649	osteoblast differentiation
0.38	GO:0048660	regulation of smooth muscle cell proliferation
0.38	GO:0010906	regulation of glucose metabolic process
0.37	GO:0090090	negative regulation of canonical Wnt signaling pathway

0.84	GO:0005520	insulin-like growth factor binding
0.39	GO:0001968	fibronectin binding
0.39	GO:0008160	protein tyrosine phosphatase activator activity
0.36	GO:0005102	receptor binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0008374	O-acyltransferase activity

0.72	GO:0042568	insulin-like growth factor binary complex
0.41	GO:0005794	Golgi apparatus
0.41	GO:0070062	extracellular exosome
0.39	GO:0042567	insulin-like growth factor ternary complex
0.35	GO:0005634	nucleus
0.35	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008374

sp|P35577|THBG_RAT
Thyroxine-binding globulin
Search

SERPINA7

0.93	Corticosteroid binding globulin

0.57	GO:0070327	thyroid hormone transport
0.53	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0033189	response to vitamin A
0.37	GO:0051412	response to corticosterone
0.36	GO:0034695	response to prostaglandin E
0.36	GO:0043434	response to peptide hormone
0.36	GO:0007568	aging
0.35	GO:0009791	post-embryonic development
0.34	GO:0042493	response to drug
0.34	GO:0002576	platelet degranulation

0.54	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0015349	thyroid hormone transmembrane transporter activity
0.36	GO:0042562	hormone binding
0.35	GO:0002020	protease binding
0.34	GO:0032190	acrosin binding
0.34	GO:0001972	retinoic acid binding
0.34	GO:0031210	phosphatidylcholine binding
0.34	GO:0005496	steroid binding
0.33	GO:0042802	identical protein binding
0.33	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.35	GO:0030141	secretory granule
0.34	GO:0097182	protein C inhibitor-coagulation factor Xa complex
0.34	GO:0097183	protein C inhibitor-coagulation factor XI complex
0.34	GO:0097181	protein C inhibitor-coagulation factor V complex
0.34	GO:0036030	protein C inhibitor-plasma kallikrein complex
0.34	GO:0036028	protein C inhibitor-thrombin complex
0.34	GO:0036029	protein C inhibitor-KLK3 complex
0.34	GO:0036024	protein C inhibitor-TMPRSS7 complex

0.33

GO:0008233

sp|P35704|PRDX2_RAT
Peroxiredoxin-2
Search

PRDX2

0.38	Natural killer cell enhancing factor

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0072593	reactive oxygen species metabolic process
0.51	GO:0071450	cellular response to oxygen radical
0.51	GO:0000303	response to superoxide
0.47	GO:0042981	regulation of apoptotic process
0.46	GO:0030101	natural killer cell activation
0.45	GO:0042267	natural killer cell mediated cytotoxicity
0.45	GO:0042345	regulation of NF-kappaB import into nucleus

0.73	GO:0051920	peroxiredoxin activity
0.52	GO:0004601	peroxidase activity
0.45	GO:0045296	cadherin binding
0.41	GO:0042802	identical protein binding
0.35	GO:0008430	selenium binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0020037	heme binding
0.32	GO:0003723	RNA binding

0.45	GO:0043209	myelin sheath
0.39	GO:0005634	nucleus
0.39	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.35	GO:0031012	extracellular matrix
0.34	GO:0031907	microbody lumen
0.34	GO:0000791	euchromatin
0.34	GO:0044439	peroxisomal part
0.33	GO:1905369	endopeptidase complex

0.73	EC:1.11.1.15	GO:0051920
0.52	KEGG:R03532	GO:0004601

sp|P35738|ODBB_RAT
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
Search

BCKDHB

0.92	Branched chain keto acid dehydrogenase E1 beta polypeptide

0.61	GO:0009083	branched-chain amino acid catabolic process
0.44	GO:0055114	oxidation-reduction process

0.61	GO:0003826	alpha-ketoacid dehydrogenase activity
0.36	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity

0.66

GO:0005947

mitochondrial alpha-ketoglutarate dehydrogenase complex

0.36

EC:1.2.4.1

GO:0004739

sp|P35739|NTRK1_RAT
High affinity nerve growth factor receptor
Search

NTRK1

0.65	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.75	GO:0038179	neurotrophin signaling pathway
0.59	GO:0061368	behavioral response to formalin induced pain
0.58	GO:0060385	axonogenesis involved in innervation
0.57	GO:1990090	cellular response to nerve growth factor stimulus
0.56	GO:0048485	sympathetic nervous system development
0.56	GO:0046579	positive regulation of Ras protein signal transduction
0.55	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.55	GO:0051965	positive regulation of synapse assembly

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.77	GO:0005030	neurotrophin receptor activity
0.59	GO:0048406	nerve growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042803	protein homodimerization activity
0.35	GO:0042289	MHC class II protein binding

0.65	GO:0005887	integral component of plasma membrane
0.53	GO:0005770	late endosome
0.52	GO:0005769	early endosome
0.52	GO:0030424	axon
0.52	GO:0043235	receptor complex
0.50	GO:0009986	cell surface

0.80

GO:0004714

sp|P35745|ACYP2_RAT
Acylphosphatase-2
Search

ACYP2

0.51	Acylphosphatase

0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.45	GO:0018108	peptidyl-tyrosine phosphorylation
0.35	GO:0046944	protein carbamoylation
0.34	GO:0051693	actin filament capping
0.33	GO:1901642	nucleoside transmembrane transport
0.33	GO:0007010	cytoskeleton organization

0.80	GO:0003998	acylphosphatase activity
0.46	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0042802	identical protein binding
0.34	GO:0003725	double-stranded RNA binding
0.34	GO:0016743	carboxyl- or carbamoyltransferase activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0005543	phospholipid binding

0.42	GO:0005739	mitochondrion
0.34	GO:0008091	spectrin
0.33	GO:0005887	integral component of plasma membrane

0.80

EC:3.6.1.7

GO:0003998

sp|P35763|PERF_RAT
Perforin-1
Search

PRF1

0.93	Perforin 1 (Pore forming protein)

0.75	GO:0019835	cytolysis
0.69	GO:0002418	immune response to tumor cell
0.69	GO:0002357	defense response to tumor cell
0.68	GO:0001771	immunological synapse formation
0.62	GO:0051712	positive regulation of killing of cells of other organism
0.59	GO:0051260	protein homooligomerization
0.59	GO:0051607	defense response to virus
0.45	GO:0055085	transmembrane transport
0.39	GO:0006915	apoptotic process
0.38	GO:0045471	response to ethanol

0.68	GO:0005509	calcium ion binding
0.58	GO:0022829	wide pore channel activity
0.57	GO:0042802	identical protein binding
0.32	GO:0003676	nucleic acid binding

0.68	GO:0044194	cytolytic granule
0.56	GO:0031410	cytoplasmic vesicle
0.53	GO:0005829	cytosol
0.49	GO:0005579	membrane attack complex
0.39	GO:0012505	endomembrane system
0.39	GO:0031974	membrane-enclosed lumen
0.39	GO:0005576	extracellular region
0.37	GO:0044446	intracellular organelle part

sp|P35815|PPM1B_RAT
Protein phosphatase 1B
Search

sp|P35859|ALS_RAT
Insulin-like growth factor-binding protein complex acid labile subunit
Search

IGFALS

0.85	Insulin like growth factor binding protein acid labile subunit

0.48	GO:0034162	toll-like receptor 9 signaling pathway
0.46	GO:0007155	cell adhesion
0.46	GO:0050729	positive regulation of inflammatory response
0.46	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.45	GO:0050707	regulation of cytokine secretion
0.45	GO:0002237	response to molecule of bacterial origin
0.44	GO:0045087	innate immune response
0.42	GO:0071549	cellular response to dexamethasone stimulus
0.42	GO:0071364	cellular response to epidermal growth factor stimulus
0.42	GO:0071378	cellular response to growth hormone stimulus

0.64	GO:0005520	insulin-like growth factor binding
0.42	GO:0004888	transmembrane signaling receptor activity
0.41	GO:0008022	protein C-terminus binding
0.40	GO:0004416	hydroxyacylglutathione hydrolase activity
0.35	GO:0005149	interleukin-1 receptor binding
0.34	GO:0003779	actin binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0017076	purine nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0042567	insulin-like growth factor ternary complex
0.63	GO:0005654	nucleoplasm
0.44	GO:0070062	extracellular exosome
0.36	GO:0036019	endolysosome
0.36	GO:0032009	early phagosome
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005886	plasma membrane
0.33	GO:0005765	lysosomal membrane
0.33	GO:0045177	apical part of cell

0.40	EC:3.1.2.6	GO:0004416
0.33	KEGG:R03362	GO:0016303

sp|P35894|GU01_RAT
Putative gustatory receptor clone PTE01 (Fragment)
Search

OR7

0.43	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.76	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.54	GO:0005886	plasma membrane
0.31	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|P35895|GU03_RAT
Putative gustatory receptor clone PTE03 (Fragment)
Search

0.39	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.38	GO:0005549	odorant binding
0.32	GO:0003676	nucleic acid binding

0.55	GO:0005886	plasma membrane
0.31	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|P35896|O1174_RAT
Olfactory receptor 1174
Search

0.45	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.69	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P35897|GU38_RAT
Putative gustatory receptor clone PTE38 (Fragment)
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P35898|O1073_RAT
Olfactory receptor 1073
Search

0.43	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005509	calcium ion binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P35899|O1571_RAT
Olfactory receptor 1571 (Fragment)
Search

OR7

0.43	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005509	calcium ion binding

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P35952|LDLR_RAT
Low-density lipoprotein receptor
Search

LDLR

0.90	Low density lipoprotein receptor a

0.56	GO:0090118	receptor-mediated endocytosis involved in cholesterol transport
0.54	GO:0061889	negative regulation of astrocyte activation
0.54	GO:1903979	negative regulation of microglial cell activation
0.54	GO:0061771	response to caloric restriction
0.53	GO:0030299	intestinal cholesterol absorption
0.53	GO:1905167	positive regulation of lysosomal protein catabolic process
0.53	GO:0010899	regulation of phosphatidylcholine catabolic process
0.53	GO:0070508	cholesterol import
0.53	GO:1905907	negative regulation of amyloid fibril formation
0.53	GO:0010986	positive regulation of lipoprotein particle clearance

0.70	GO:0005509	calcium ion binding
0.55	GO:0005041	low-density lipoprotein receptor activity
0.53	GO:0030229	very-low-density lipoprotein particle receptor activity
0.53	GO:0030169	low-density lipoprotein particle binding
0.50	GO:0001540	amyloid-beta binding
0.50	GO:0002020	protease binding
0.46	GO:0042802	identical protein binding
0.33	GO:0032050	clathrin heavy chain binding
0.33	GO:0104005	hijacked molecular function
0.33	GO:0004930	G-protein coupled receptor activity

0.54	GO:1990666	PCSK9-LDLR complex
0.52	GO:0097443	sorting endosome
0.50	GO:0005905	clathrin-coated pit
0.50	GO:0005770	late endosome
0.50	GO:0005769	early endosome
0.49	GO:0005764	lysosome
0.49	GO:0009897	external side of plasma membrane
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0043235	receptor complex
0.48	GO:0045177	apical part of cell

sp|P36198|LHX2_RAT
LIM/homeobox protein Lhx2
Search

LHX2

0.97	Lim homeobox transcription factor 2

0.63	GO:0030900	forebrain development
0.62	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.61	GO:0007411	axon guidance
0.61	GO:0043010	camera-type eye development
0.61	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.60	GO:0048675	axon extension
0.59	GO:0001843	neural tube closure
0.58	GO:0007498	mesoderm development
0.58	GO:0009953	dorsal/ventral pattern formation
0.57	GO:0001942	hair follicle development

0.63	GO:0043565	sequence-specific DNA binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003682	chromatin binding
0.53	GO:0046872	metal ion binding
0.52	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|P36201|CRIP2_RAT
Cysteine-rich protein 2
Search

0.51	Cysteine-rich protein 3

0.43	GO:0030097	hemopoiesis
0.43	GO:0008284	positive regulation of cell proliferation

0.54	GO:0046872	metal ion binding
0.43	GO:0046982	protein heterodimerization activity
0.37	GO:0003677	DNA binding

0.43	GO:0000786	nucleosome
0.42	GO:0005938	cell cortex
0.42	GO:0031012	extracellular matrix
0.39	GO:0005634	nucleus

sp|P36202|PDLI4_RAT
PDZ and LIM domain protein 4
Search

PDLIM4

0.97	PDZ and LIM domain protein 4

0.55	GO:0031532	actin cytoskeleton reorganization
0.45	GO:0098976	excitatory chemical synaptic transmission
0.40	GO:0098609	cell-cell adhesion
0.36	GO:0051496	positive regulation of stress fiber assembly
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0001666	response to hypoxia
0.35	GO:0060173	limb development
0.34	GO:0055085	transmembrane transport

0.61	GO:0051393	alpha-actinin binding
0.59	GO:0019903	protein phosphatase binding
0.54	GO:0042803	protein homodimerization activity
0.53	GO:0046872	metal ion binding
0.42	GO:0098641	cadherin binding involved in cell-cell adhesion
0.40	GO:0003713	transcription coactivator activity
0.34	GO:0051015	actin filament binding
0.34	GO:0022857	transmembrane transporter activity

0.60	GO:0097517	contractile actin filament bundle
0.60	GO:0031941	filamentous actin
0.60	GO:0042641	actomyosin
0.58	GO:0030027	lamellipodium
0.56	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.45	GO:0034777	recycling endosome lumen
0.45	GO:0031905	early endosome lumen
0.43	GO:0030054	cell junction
0.43	GO:0055038	recycling endosome membrane

sp|P36364|FGF9_RAT
Fibroblast growth factor 9
Search

FGF9

0.62	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.59	GO:0060043	regulation of cardiac muscle cell proliferation
0.58	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.57	GO:0048839	inner ear development
0.56	GO:0060484	lung-associated mesenchyme development
0.56	GO:0032927	positive regulation of activin receptor signaling pathway
0.56	GO:0008584	male gonad development
0.56	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.56	GO:0048505	regulation of timing of cell differentiation

0.83	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.48	GO:0090722	receptor-receptor interaction
0.41	GO:0008201	heparin binding
0.38	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity
0.34	GO:0043395	heparan sulfate proteoglycan binding

0.65	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38	EC:2.7.1.153	GO:0046934
0.38	KEGG:R04545	GO:0046934

sp|P36365|FMO1_RAT
Dimethylaniline monooxygenase [N-oxide-forming] 1
Search

FMO1

0.59	Flavin-containing monooxygenase

0.63	GO:0070995	NADPH oxidation
0.51	GO:0009404	toxin metabolic process
0.47	GO:0072592	oxygen metabolic process
0.44	GO:0006082	organic acid metabolic process
0.43	GO:0006805	xenobiotic metabolic process
0.40	GO:0042737	drug catabolic process
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:0006970	response to osmotic stress

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.69	GO:0050661	NADP binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0034899	trimethylamine monooxygenase activity
0.34	GO:0005515	protein binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.78	EC:1.14.13.8	GO:0004499
0.37	KEGG:R05623	GO:0034899

sp|P36370|TAP1_RAT
Antigen peptide transporter 1
Search

TAP1

0.94	Transporter associated with antigen processing 1

0.85	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.65	GO:0042886	amide transport
0.61	GO:0071702	organic substance transport
0.59	GO:0046967	cytosol to ER transport
0.55	GO:0055085	transmembrane transport
0.49	GO:0006952	defense response
0.43	GO:0002488	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
0.43	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.42	GO:0001910	regulation of leukocyte mediated cytotoxicity
0.42	GO:0002706	regulation of lymphocyte mediated immunity

0.85	GO:0042287	MHC protein binding
0.85	GO:0015440	peptide-transporting ATPase activity
0.84	GO:0046977	TAP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0046980	tapasin binding
0.39	GO:0042605	peptide antigen binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.86	GO:0042825	TAP complex
0.50	GO:0005815	microtubule organizing center
0.44	GO:0005739	mitochondrion
0.39	GO:0030670	phagocytic vesicle membrane
0.37	GO:0042613	MHC class II protein complex
0.37	GO:0016607	nuclear speck
0.36	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0005839	proteasome core complex
0.32	GO:0005887	integral component of plasma membrane

0.85

EC:3.6.3.43

GO:0015440

sp|P36372|TAP2_RAT
Antigen peptide transporter 2
Search

TAP2

0.31	Major histocompatibility complex class I

0.85	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.64	GO:0042886	amide transport
0.61	GO:0071702	organic substance transport
0.55	GO:0055085	transmembrane transport
0.52	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
0.50	GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
0.49	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.48	GO:0046967	cytosol to ER transport
0.46	GO:0002237	response to molecule of bacterial origin
0.43	GO:0006955	immune response

0.85	GO:0042287	MHC protein binding
0.85	GO:0015440	peptide-transporting ATPase activity
0.64	GO:0046977	TAP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046980	tapasin binding
0.38	GO:0042605	peptide antigen binding
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0046982	protein heterodimerization activity

0.86	GO:0042825	TAP complex
0.41	GO:0005815	microtubule organizing center
0.40	GO:0016607	nuclear speck
0.40	GO:0042613	MHC class II protein complex
0.38	GO:0005739	mitochondrion
0.37	GO:0030670	phagocytic vesicle membrane
0.36	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0005839	proteasome core complex
0.33	GO:0005887	integral component of plasma membrane

0.85

EC:3.6.3.43

GO:0015440

sp|P36373|KLK7_RAT
Glandular kallikrein-7, submandibular/renal
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.41	GO:0002675	positive regulation of acute inflammatory response
0.40	GO:0007584	response to nutrient
0.39	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043065	positive regulation of apoptotic process
0.39	GO:0002778	antibacterial peptide production
0.38	GO:0051604	protein maturation
0.38	GO:0008015	blood circulation
0.37	GO:0035296	regulation of tube diameter
0.37	GO:0003018	vascular process in circulatory system

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0008083	growth factor activity
0.34	GO:0046872	metal ion binding

0.48	GO:0005615	extracellular space
0.42	GO:0030141	secretory granule
0.41	GO:1903561	extracellular vesicle
0.41	GO:0005634	nucleus
0.40	GO:0043234	protein complex
0.40	GO:0097223	sperm part
0.40	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P36374|KLK6_RAT
Prostatic glandular kallikrein-6
Search

0.97	Epidermal growth factor-binding protein type B

0.61	GO:0006508	proteolysis
0.41	GO:0032101	regulation of response to external stimulus
0.40	GO:0031349	positive regulation of defense response
0.40	GO:0032501	multicellular organismal process
0.39	GO:0050878	regulation of body fluid levels
0.39	GO:0009611	response to wounding
0.39	GO:0007584	response to nutrient
0.39	GO:0042981	regulation of apoptotic process
0.38	GO:0008284	positive regulation of cell proliferation
0.38	GO:0043068	positive regulation of programmed cell death

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.38	GO:0005509	calcium ion binding
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0005102	receptor binding
0.35	GO:0030545	receptor regulator activity
0.35	GO:0090729	toxin activity
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0019899	enzyme binding
0.32	GO:0043395	heparan sulfate proteoglycan binding

0.47	GO:0005615	extracellular space
0.41	GO:0030141	secretory granule
0.40	GO:1903561	extracellular vesicle
0.40	GO:0043234	protein complex
0.39	GO:0097223	sperm part
0.39	GO:0005634	nucleus
0.39	GO:0045177	apical part of cell
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P36375|KLK10_RAT
Glandular kallikrein-10
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.40	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0002778	antibacterial peptide production
0.39	GO:0007584	response to nutrient
0.39	GO:0008284	positive regulation of cell proliferation
0.38	GO:0043065	positive regulation of apoptotic process
0.38	GO:0051604	protein maturation
0.37	GO:0008015	blood circulation
0.36	GO:0035296	regulation of tube diameter
0.36	GO:0003018	vascular process in circulatory system

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0005102	receptor binding
0.35	GO:0030545	receptor regulator activity
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0090729	toxin activity
0.34	GO:0046872	metal ion binding
0.34	GO:0019899	enzyme binding
0.32	GO:0043395	heparan sulfate proteoglycan binding

0.48	GO:0005615	extracellular space
0.41	GO:0030141	secretory granule
0.40	GO:1903561	extracellular vesicle
0.40	GO:0043234	protein complex
0.39	GO:0005634	nucleus
0.39	GO:0097223	sperm part
0.39	GO:0045177	apical part of cell
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P36376|KLK12_RAT
Glandular kallikrein-12, submandibular/renal
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.41	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0007584	response to nutrient
0.39	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043065	positive regulation of apoptotic process
0.39	GO:0002778	antibacterial peptide production
0.38	GO:0032501	multicellular organismal process
0.38	GO:0051604	protein maturation
0.36	GO:0035296	regulation of tube diameter
0.36	GO:0009653	anatomical structure morphogenesis

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0008083	growth factor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005044	scavenger receptor activity
0.32	GO:0003746	translation elongation factor activity

0.48	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.40	GO:0030141	secretory granule
0.40	GO:0043234	protein complex
0.40	GO:0005634	nucleus
0.39	GO:0097223	sperm part
0.39	GO:0045177	apical part of cell
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P36380|CXB4_RAT
Gap junction beta-4 protein
Search

0.64	Gap junction beta-4 protein (Fragment)

0.59	GO:0007154	cell communication
0.55	GO:0001890	placenta development
0.53	GO:0042048	olfactory behavior
0.49	GO:0001701	in utero embryonic development
0.49	GO:0007608	sensory perception of smell
0.48	GO:0048568	embryonic organ development
0.47	GO:0048598	embryonic morphogenesis
0.46	GO:0009888	tissue development
0.45	GO:0030154	cell differentiation
0.39	GO:1905867	epididymis development

0.34	GO:0005243	gap junction channel activity
0.33	GO:0005515	protein binding

0.82	GO:0005922	connexin complex
0.47	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P36394|SRY_RAT
Sex-determining region Y protein (Fragment)
Search

SRY

0.69	Sex-determining region Y protein (Fragment)

0.85	GO:0030238	male sex determination
0.80	GO:0007548	sex differentiation
0.71	GO:0030154	cell differentiation
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0048608	reproductive structure development
0.37	GO:2000020	positive regulation of male gonad development
0.37	GO:0048513	animal organ development

0.78	GO:0005516	calmodulin binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0008134	transcription factor binding
0.34	GO:0019899	enzyme binding

0.79	GO:0016607	nuclear speck
0.37	GO:0044798	nuclear transcription factor complex
0.36	GO:0005737	cytoplasm

sp|P36407|TRI23_RAT
E3 ubiquitin-protein ligase TRIM23
Search

TRIM23

0.53	GTP-binding protein ARD-1

0.50	GO:0016567	protein ubiquitination
0.35	GO:0006471	protein ADP-ribosylation
0.34	GO:0045087	innate immune response
0.34	GO:0043085	positive regulation of catalytic activity
0.33	GO:0016032	viral process
0.33	GO:0010898	positive regulation of triglyceride catabolic process
0.32	GO:0016042	lipid catabolic process

0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.62	GO:0008270	zinc ion binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042802	identical protein binding
0.50	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0016874	ligase activity
0.49	GO:0003676	nucleic acid binding
0.48	GO:0003924	GTPase activity

0.54	GO:0005765	lysosomal membrane
0.51	GO:0000139	Golgi membrane
0.45	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.50	EC:6	GO:0016874
0.50	KEGG:R03876	GO:0004842

sp|P36506|MP2K2_RAT
Dual specificity mitogen-activated protein kinase kinase 2
Search

MAP2K2

0.91	Dual specificity mitogen-activated protein kinase kinase 2

0.63	GO:0006468	protein phosphorylation
0.56	GO:0060502	epithelial cell proliferation involved in lung morphogenesis
0.55	GO:0060440	trachea formation
0.54	GO:0030878	thyroid gland development
0.53	GO:0048679	regulation of axon regeneration
0.53	GO:0048538	thymus development
0.53	GO:0060324	face development
0.53	GO:0050772	positive regulation of axonogenesis
0.51	GO:0001932	regulation of protein phosphorylation
0.50	GO:0007507	heart development

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0032947	protein complex scaffold activity
0.47	GO:0004708	MAP kinase kinase activity
0.46	GO:0097110	scaffold protein binding
0.46	GO:0043539	protein serine/threonine kinase activator activity
0.43	GO:0030165	PDZ domain binding

0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0030054	cell junction
0.41	GO:0015630	microtubule cytoskeleton
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0044430	cytoskeletal part
0.40	GO:0005794	Golgi apparatus
0.40	GO:0099512	supramolecular fiber
0.39	GO:0005829	cytosol
0.38	GO:0005770	late endosome

0.68

GO:0004674

sp|P36510|UD2A1_RAT
UDP-glucuronosyltransferase 2A1
Search

0.54	UDP-glucuronosyltransferase

0.55	GO:0052695	cellular glucuronidation
0.38	GO:0008202	steroid metabolic process
0.37	GO:0007608	sensory perception of smell
0.37	GO:0034754	cellular hormone metabolic process
0.37	GO:0006805	xenobiotic metabolic process
0.35	GO:0018879	biphenyl metabolic process
0.35	GO:0071394	cellular response to testosterone stimulus
0.35	GO:0009636	response to toxic substance
0.34	GO:0071378	cellular response to growth hormone stimulus
0.34	GO:0071385	cellular response to glucocorticoid stimulus

0.80	GO:0015020	glucuronosyltransferase activity
0.40	GO:0001972	retinoic acid binding

0.42	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.38	GO:0031090	organelle membrane
0.36	GO:0044444	cytoplasmic part
0.34	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

GO:0015020

sp|P36511|UDB15_RAT
UDP-glucuronosyltransferase 2B15
Search

0.54	UDP-glucuronosyltransferase

0.49	GO:0052695	cellular glucuronidation
0.39	GO:0008209	androgen metabolic process
0.38	GO:0071394	cellular response to testosterone stimulus
0.38	GO:0071361	cellular response to ethanol
0.38	GO:0071378	cellular response to growth hormone stimulus
0.38	GO:0071385	cellular response to glucocorticoid stimulus
0.37	GO:0070980	biphenyl catabolic process
0.37	GO:0032496	response to lipopolysaccharide
0.33	GO:0007608	sensory perception of smell
0.33	GO:0009593	detection of chemical stimulus

0.80	GO:0015020	glucuronosyltransferase activity
0.41	GO:0001972	retinoic acid binding

0.43	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0044429	mitochondrial part
0.34	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

0.80

GO:0015020

sp|P36576|ARRC_RAT
Arrestin-C (Fragment)
Search

0.73	Arrestin-C (Fragment)

0.61	GO:0007165	signal transduction
0.47	GO:0001932	regulation of protein phosphorylation
0.47	GO:0006897	endocytosis
0.41	GO:0007601	visual perception
0.36	GO:0040010	positive regulation of growth rate
0.35	GO:0009966	regulation of signal transduction
0.34	GO:0048523	negative regulation of cellular process
0.34	GO:0023057	negative regulation of signaling
0.34	GO:0048585	negative regulation of response to stimulus
0.34	GO:0071482	cellular response to light stimulus

0.61	GO:0002046	opsin binding
0.57	GO:0051219	phosphoprotein binding
0.35	GO:0019904	protein domain specific binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.34	GO:0004864	protein phosphatase inhibitor activity
0.33	GO:0008289	lipid binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0001917	photoreceptor inner segment
0.57	GO:0001750	photoreceptor outer segment
0.48	GO:0045202	synapse
0.33	GO:0043204	perikaryon
0.33	GO:0030425	dendrite
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P36577|ARRD_RAT
Arrestin-D (Fragment)
Search

0.10	Arrestin-D (Fragment)

0.56

GO:0050896

response to stimulus

sp|P36633|AOC1_RAT
Amiloride-sensitive amine oxidase [copper-containing]
Search

AOC1

0.50	Amiloride-sensitive amine oxidase [copper-containing]

0.70	GO:0009308	amine metabolic process
0.61	GO:0097185	cellular response to azide
0.61	GO:0035874	cellular response to copper ion starvation
0.59	GO:0071420	cellular response to histamine
0.58	GO:0071280	cellular response to copper ion
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0046677	response to antibiotic
0.50	GO:0007601	visual perception
0.49	GO:0042493	response to drug
0.36	GO:0043312	neutrophil degranulation

0.83	GO:0008131	primary amine oxidase activity
0.72	GO:0048038	quinone binding
0.72	GO:0005507	copper ion binding
0.61	GO:0052597	diamine oxidase activity
0.54	GO:0008201	heparin binding
0.51	GO:0032403	protein complex binding
0.48	GO:0042803	protein homodimerization activity
0.46	GO:0005509	calcium ion binding
0.46	GO:0004872	receptor activity
0.45	GO:0008270	zinc ion binding

0.51	GO:0070062	extracellular exosome
0.48	GO:0005923	bicellular tight junction
0.42	GO:0005886	plasma membrane
0.36	GO:0035580	specific granule lumen
0.35	GO:0008537	proteasome activator complex
0.35	GO:0005777	peroxisome
0.34	GO:0005902	microvillus
0.34	GO:0005769	early endosome
0.33	GO:0009986	cell surface
0.33	GO:0005794	Golgi apparatus

0.83	EC:1.4.3.21	GO:0008131
0.83	KEGG:R01853	GO:0008131

sp|P36860|RALB_RAT
Ras-related protein Ral-B
Search

RALB

0.45	RAS like proto-oncogene B

0.83	GO:0007265	Ras protein signal transduction
0.55	GO:0071360	cellular response to exogenous dsRNA
0.55	GO:2000786	positive regulation of autophagosome assembly
0.53	GO:0032092	positive regulation of protein binding
0.53	GO:0032091	negative regulation of protein binding
0.51	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.50	GO:0009267	cellular response to starvation
0.46	GO:0017157	regulation of exocytosis
0.45	GO:0051665	membrane raft localization
0.44	GO:0051491	positive regulation of filopodium assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.57	GO:0051117	ATPase binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.43	GO:0017022	myosin binding
0.35	GO:0004713	protein tyrosine kinase activity

0.56	GO:0005886	plasma membrane
0.54	GO:0030496	midbody
0.52	GO:0005776	autophagosome
0.50	GO:0000145	exocyst
0.44	GO:0097610	cell surface furrow
0.43	GO:0032155	cell division site part
0.42	GO:0030139	endocytic vesicle
0.42	GO:0043209	myelin sheath
0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.35

GO:0004713

sp|P36876|2ABA_RAT
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
Search

PPP2R2A

0.66	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B

0.78	GO:0043666	regulation of phosphoprotein phosphatase activity
0.55	GO:0043278	response to morphine
0.49	GO:0006470	protein dephosphorylation
0.43	GO:0032502	developmental process
0.43	GO:0000278	mitotic cell cycle
0.38	GO:0032501	multicellular organismal process
0.35	GO:0031468	nuclear envelope reassembly
0.35	GO:0044839	cell cycle G2/M phase transition
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0043065	positive regulation of apoptotic process

0.79	GO:0019888	protein phosphatase regulator activity
0.51	GO:0004722	protein serine/threonine phosphatase activity
0.40	GO:0048156	tau protein binding
0.39	GO:0051721	protein phosphatase 2A binding
0.37	GO:0032403	protein complex binding

0.80	GO:0000159	protein phosphatase type 2A complex
0.41	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.33	GO:0005740	mitochondrial envelope
0.30	GO:0031224	intrinsic component of membrane

sp|P36877|2ABB_RAT
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Search

PPP2R2B

0.66	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.47	GO:0070262	peptidyl-serine dephosphorylation
0.43	GO:0000278	mitotic cell cycle
0.41	GO:0032502	developmental process
0.37	GO:0006915	apoptotic process
0.35	GO:0043525	positive regulation of neuron apoptotic process
0.35	GO:0000266	mitochondrial fission
0.34	GO:0007283	spermatogenesis
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism
0.34	GO:0006626	protein targeting to mitochondrion

0.80	GO:0019888	protein phosphatase regulator activity
0.44	GO:0004722	protein serine/threonine phosphatase activity
0.34	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.42	GO:0005829	cytosol
0.40	GO:0005856	cytoskeleton
0.37	GO:0005741	mitochondrial outer membrane

sp|P36940|TNFL6_RAT
Tumor necrosis factor ligand superfamily member 6
Search

FASLG

0.97	Tumor necrosis factor ligand superfamily member 6

0.73	GO:0006955	immune response
0.71	GO:0006915	apoptotic process
0.69	GO:0010469	regulation of receptor activity
0.67	GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum
0.67	GO:0097527	necroptotic signaling pathway
0.66	GO:2000353	positive regulation of endothelial cell apoptotic process
0.66	GO:0046666	retinal cell programmed cell death
0.63	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.62	GO:0016525	negative regulation of angiogenesis
0.62	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.83	GO:0005164	tumor necrosis factor receptor binding
0.73	GO:0005125	cytokine activity
0.45	GO:0005123	death receptor binding

0.68	GO:0005615	extracellular space
0.60	GO:1903561	extracellular vesicle
0.59	GO:0009897	external side of plasma membrane
0.49	GO:0005634	nucleus
0.49	GO:0043202	lysosomal lumen
0.49	GO:0060205	cytoplasmic vesicle lumen
0.43	GO:0005901	caveola
0.42	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005887	integral component of plasma membrane

sp|P36953|AFAM_RAT
Afamin
Search

AFM

0.97	LOW QUALITY PROTEIN: afamin

0.72	GO:0071693	protein transport within extracellular region
0.61	GO:0050821	protein stabilization
0.58	GO:0051180	vitamin transport
0.36	GO:0001542	ovulation from ovarian follicle
0.36	GO:0042448	progesterone metabolic process
0.36	GO:0051659	maintenance of mitochondrion location
0.35	GO:0060395	SMAD protein signal transduction
0.35	GO:0019836	hemolysis by symbiont of host erythrocytes
0.34	GO:0009267	cellular response to starvation
0.34	GO:0043066	negative regulation of apoptotic process

0.71	GO:0008431	vitamin E binding
0.37	GO:0005515	protein binding
0.35	GO:0005504	fatty acid binding
0.35	GO:0015643	toxic substance binding
0.35	GO:0019825	oxygen binding
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.42	GO:1903561	extracellular vesicle
0.35	GO:0043209	myelin sheath
0.34	GO:0005794	Golgi apparatus
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0043234	protein complex

sp|P36972|APT_RAT
Adenine phosphoribosyltransferase
Search

APRT

0.47	Adenine phosphoribosyltransferase

0.77	GO:0006168	adenine salvage
0.66	GO:0009116	nucleoside metabolic process
0.57	GO:0044209	AMP salvage
0.54	GO:0007625	grooming behavior
0.54	GO:1901659	glycosyl compound biosynthetic process
0.38	GO:0007595	lactation
0.38	GO:0032869	cellular response to insulin stimulus
0.35	GO:0043312	neutrophil degranulation

0.78	GO:0003999	adenine phosphoribosyltransferase activity
0.57	GO:0002055	adenine binding
0.50	GO:0016208	AMP binding
0.34	GO:0008484	sulfuric ester hydrolase activity
0.32	GO:0003723	RNA binding

0.48	GO:0005737	cytoplasm
0.46	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.78

EC:2.4.2.7

GO:0003999

sp|P37089|SCNNA_RAT
Amiloride-sensitive sodium channel subunit alpha
Search

SCNN1A

0.97	Amiloride-sensitive sodium channel subunit alpha

0.77	GO:0035725	sodium ion transmembrane transport
0.61	GO:0055078	sodium ion homeostasis
0.60	GO:0050891	multicellular organismal water homeostasis
0.44	GO:0050909	sensory perception of taste
0.37	GO:0050896	response to stimulus
0.36	GO:0008217	regulation of blood pressure
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0016567	protein ubiquitination

0.85	GO:0015280	ligand-gated sodium channel activity
0.59	GO:0050699	WW domain binding
0.35	GO:0003779	actin binding
0.34	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0008270	zinc ion binding

0.60	GO:0060170	ciliary membrane
0.59	GO:0034706	sodium channel complex
0.58	GO:0016324	apical plasma membrane
0.57	GO:0031514	motile cilium
0.55	GO:0070062	extracellular exosome
0.50	GO:0005887	integral component of plasma membrane
0.40	GO:0005737	cytoplasm
0.38	GO:0009897	external side of plasma membrane
0.37	GO:0015629	actin cytoskeleton
0.35	GO:0044430	cytoskeletal part

sp|P37090|SCNNB_RAT
Amiloride-sensitive sodium channel subunit beta
Search

SCNN1B

0.97	Amiloride-sensitive sodium channel subunit beta

0.77	GO:0035725	sodium ion transmembrane transport
0.65	GO:0055078	sodium ion homeostasis
0.64	GO:0050891	multicellular organismal water homeostasis
0.44	GO:0050909	sensory perception of taste
0.37	GO:0050896	response to stimulus
0.37	GO:0090504	epiboly
0.36	GO:0002028	regulation of sodium ion transport
0.36	GO:0007588	excretion
0.36	GO:0016477	cell migration

0.85	GO:0015280	ligand-gated sodium channel activity
0.64	GO:0050699	WW domain binding

0.62	GO:0034706	sodium channel complex
0.60	GO:0009897	external side of plasma membrane
0.60	GO:0070062	extracellular exosome
0.52	GO:0005887	integral component of plasma membrane
0.47	GO:0016324	apical plasma membrane
0.45	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0005654	nucleoplasm
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0060170	ciliary membrane
0.33	GO:0031514	motile cilium

sp|P37091|SCNNG_RAT
Amiloride-sensitive sodium channel subunit gamma
Search

SCNN1G

0.97	Amiloride-sensitive sodium channel subunit gamma

0.77	GO:0035725	sodium ion transmembrane transport
0.65	GO:0055078	sodium ion homeostasis
0.64	GO:0050891	multicellular organismal water homeostasis
0.46	GO:0050909	sensory perception of taste
0.38	GO:0050896	response to stimulus
0.36	GO:0090504	epiboly
0.36	GO:0007588	excretion
0.35	GO:0016477	cell migration
0.33	GO:0008217	regulation of blood pressure

0.85	GO:0015280	ligand-gated sodium channel activity
0.64	GO:0050699	WW domain binding
0.33	GO:0003779	actin binding

0.63	GO:0034706	sodium channel complex
0.60	GO:0070062	extracellular exosome
0.58	GO:0009897	external side of plasma membrane
0.52	GO:0005887	integral component of plasma membrane
0.50	GO:0016324	apical plasma membrane
0.50	GO:0005654	nucleoplasm
0.44	GO:0060170	ciliary membrane
0.43	GO:0031514	motile cilium
0.35	GO:0005737	cytoplasm
0.35	GO:0012506	vesicle membrane

sp|P37136|ACES_RAT
Acetylcholinesterase
Search

ACHE

0.44	Carboxylic ester hydrolase

0.59	GO:0006581	acetylcholine catabolic process
0.55	GO:0045212	neurotransmitter receptor biosynthetic process
0.55	GO:0002076	osteoblast development
0.52	GO:0001919	regulation of receptor recycling
0.52	GO:0031623	receptor internalization
0.50	GO:0060041	retina development in camera-type eye
0.49	GO:0051262	protein tetramerization
0.47	GO:0007155	cell adhesion
0.44	GO:0071405	cellular response to methanol
0.42	GO:0050808	synapse organization

0.83	GO:0004104	cholinesterase activity
0.55	GO:0042166	acetylcholine binding
0.54	GO:0043236	laminin binding
0.52	GO:0005518	collagen binding
0.51	GO:0043621	protein self-association
0.51	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.45	GO:0017171	serine hydrolase activity
0.37	GO:0001540	amyloid-beta binding
0.35	GO:0033265	choline binding

0.52	GO:0005605	basal lamina
0.51	GO:0045202	synapse
0.50	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0009986	cell surface
0.47	GO:0012505	endomembrane system
0.47	GO:0005615	extracellular space
0.42	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0030054	cell junction
0.41	GO:0005886	plasma membrane
0.41	GO:0031225	anchored component of membrane

0.83

EC:3.1.1.8

GO:0004104

sp|P37199|NU155_RAT
Nuclear pore complex protein Nup155
Search

NUP155

0.79	Nuclear pore complex protein Nup155

0.72	GO:0006913	nucleocytoplasmic transport
0.60	GO:0086014	atrial cardiac muscle cell action potential
0.58	GO:0006998	nuclear envelope organization
0.56	GO:0034504	protein localization to nucleus
0.55	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.54	GO:0017038	protein import
0.53	GO:0072594	establishment of protein localization to organelle
0.53	GO:0051028	mRNA transport
0.49	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
0.44	GO:0072657	protein localization to membrane

0.80	GO:0017056	structural constituent of nuclear pore
0.35	GO:0005515	protein binding
0.35	GO:0015288	porin activity

0.78	GO:0005643	nuclear pore
0.54	GO:0031965	nuclear membrane
0.35	GO:0046930	pore complex
0.34	GO:0044215	other organism
0.32	GO:0005737	cytoplasm

sp|P37200|ARRE_RAT
Arrestin-E (Fragment)
Search

0.10	Arrestin-E (Fragment)

0.56

GO:0050896

response to stimulus

sp|P37230|PPARA_RAT
Peroxisome proliferator-activated receptor alpha
Search

PPARA

0.96	Peroxisome proliferator-activated receptor alpha

0.78	GO:0030522	intracellular receptor signaling pathway
0.76	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
0.59	GO:0072363	regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
0.58	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
0.58	GO:0010887	negative regulation of cholesterol storage
0.58	GO:0010871	negative regulation of receptor biosynthetic process
0.58	GO:0010891	negative regulation of sequestering of triglyceride
0.58	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.57	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II

0.80	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.56	GO:0001103	RNA polymerase II repressing transcription factor binding
0.56	GO:0031624	ubiquitin conjugating enzyme binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.53	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding

0.60	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part

sp|P37285|KLC1_RAT
Kinesin light chain 1
Search

KLC1

0.81	Kinesin light chain 1

0.46	GO:0097193	intrinsic apoptotic signaling pathway
0.40	GO:0035617	stress granule disassembly
0.38	GO:0035418	protein localization to synapse
0.38	GO:0008088	axo-dendritic transport
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0006886	intracellular protein transport
0.35	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.33	GO:0016032	viral process

0.73	GO:0003777	microtubule motor activity
0.36	GO:0005515	protein binding

0.80	GO:0005871	kinesin complex
0.41	GO:0030426	growth cone
0.39	GO:0031982	vesicle
0.38	GO:0030424	axon
0.38	GO:0005874	microtubule
0.38	GO:0035253	ciliary rootlet
0.37	GO:0043025	neuronal cell body
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P37361|MT3_RAT
Metallothionein-3
Search

0.75	Metallothionein-II, hippocampal

0.58	GO:0071248	cellular response to metal ion
0.57	GO:0045926	negative regulation of growth
0.57	GO:0097214	positive regulation of lysosomal membrane permeability
0.56	GO:2000376	positive regulation of oxygen metabolic process
0.56	GO:0055073	cadmium ion homeostasis
0.55	GO:0010940	positive regulation of necrotic cell death
0.55	GO:0060547	negative regulation of necrotic cell death
0.55	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.54	GO:0071732	cellular response to nitric oxide
0.54	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress

0.55	GO:0046870	cadmium ion binding
0.54	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.51	GO:0030295	protein kinase activator activity
0.48	GO:0008270	zinc ion binding
0.47	GO:0005507	copper ion binding
0.40	GO:0008144	drug binding
0.35	GO:0005515	protein binding
0.34	GO:0016209	antioxidant activity

0.56	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0016234	inclusion body
0.51	GO:0008021	synaptic vesicle
0.43	GO:0005634	nucleus
0.42	GO:0097450	astrocyte end-foot
0.41	GO:0043197	dendritic spine
0.40	GO:0014069	postsynaptic density
0.40	GO:0005791	rough endoplasmic reticulum
0.40	GO:0030424	axon
0.39	GO:0005741	mitochondrial outer membrane

sp|P37377|SYUA_RAT
Alpha-synuclein
Search

SNCA

0.97	Alpha-synuclein

0.82	GO:0014059	regulation of dopamine secretion
0.60	GO:0042417	dopamine metabolic process
0.59	GO:0051945	negative regulation of catecholamine uptake involved in synaptic transmission
0.59	GO:0051621	regulation of norepinephrine uptake
0.59	GO:1903284	positive regulation of glutathione peroxidase activity
0.59	GO:1903285	positive regulation of hydrogen peroxide catabolic process
0.59	GO:1904715	negative regulation of chaperone-mediated autophagy
0.59	GO:0032227	negative regulation of synaptic transmission, dopaminergic
0.58	GO:0043524	negative regulation of neuron apoptotic process
0.58	GO:0051612	negative regulation of serotonin uptake

0.62	GO:1903136	cuprous ion binding
0.57	GO:0048156	tau protein binding
0.57	GO:0050544	arachidonic acid binding
0.56	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.55	GO:0043014	alpha-tubulin binding
0.55	GO:0030544	Hsp70 protein binding
0.54	GO:0019894	kinesin binding
0.54	GO:0070840	dynein complex binding
0.54	GO:0051219	phosphoprotein binding
0.52	GO:0042393	histone binding

0.59	GO:0016234	inclusion body
0.57	GO:0031092	platelet alpha granule membrane
0.56	GO:0045202	synapse
0.54	GO:0030426	growth cone
0.53	GO:0043025	neuronal cell body
0.52	GO:0030424	axon
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005615	extracellular space
0.50	GO:0005938	cell cortex
0.49	GO:0005829	cytosol

0.41

GO:0016491

sp|P37397|CNN3_RAT
Calponin-3
Search

CNN3

0.87

Calponin

0.82	GO:0031032	actomyosin structure organization
0.51	GO:0030855	epithelial cell differentiation
0.50	GO:0098609	cell-cell adhesion
0.37	GO:0032780	negative regulation of ATPase activity
0.36	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.34	GO:1904706	negative regulation of vascular smooth muscle cell proliferation

0.77	GO:0005516	calmodulin binding
0.74	GO:0003779	actin binding
0.55	GO:0098641	cadherin binding involved in cell-cell adhesion
0.37	GO:0008017	microtubule binding
0.30	GO:0060090	molecular adaptor activity

0.52	GO:0005913	cell-cell adherens junction
0.48	GO:0015629	actin cytoskeleton
0.46	GO:0005829	cytosol
0.37	GO:0043197	dendritic spine
0.37	GO:0014069	postsynaptic density
0.37	GO:0043025	neuronal cell body
0.35	GO:0005925	focal adhesion
0.30	GO:0099081	supramolecular polymer
0.30	GO:0044422	organelle part
0.30	GO:0015630	microtubule cytoskeleton

sp|P37727|RAE1_RAT
Rab proteins geranylgeranyltransferase component A 1
Search

CHM

0.94	Rab proteins geranylgeranyltransferase component A 1

0.84	GO:0018344	protein geranylgeranylation
0.77	GO:0007264	small GTPase mediated signal transduction
0.69	GO:0006886	intracellular protein transport
0.69	GO:0050790	regulation of catalytic activity
0.48	GO:0090150	establishment of protein localization to membrane
0.44	GO:0048798	swim bladder inflation
0.43	GO:0050935	iridophore differentiation
0.43	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.42	GO:0010842	retina layer formation
0.42	GO:0042491	inner ear auditory receptor cell differentiation

0.83	GO:0005092	GDP-dissociation inhibitor activity
0.54	GO:0017137	Rab GTPase binding
0.44	GO:0016740	transferase activity
0.39	GO:0005096	GTPase activator activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0032403	protein complex binding
0.34	GO:0004930	G-protein coupled receptor activity

0.84	GO:0005968	Rab-protein geranylgeranyltransferase complex
0.48	GO:0005829	cytosol
0.40	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.44

GO:0016740

sp|P37805|TAGL3_RAT
Transgelin-3
Search

TAGLN3

0.81	Transgelin

0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0030855	epithelial cell differentiation
0.36	GO:0000902	cell morphogenesis
0.36	GO:0030036	actin cytoskeleton organization
0.34	GO:0002576	platelet degranulation
0.34	GO:0007417	central nervous system development
0.34	GO:0006508	proteolysis

0.71	GO:0051015	actin filament binding
0.43	GO:0045296	cadherin binding
0.34	GO:0004252	serine-type endopeptidase activity

0.51	GO:0043209	myelin sheath
0.43	GO:0005634	nucleus
0.36	GO:0015629	actin cytoskeleton
0.35	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

GO:0004252

sp|P37996|ARL3_RAT
ADP-ribosylation factor-like protein 3
Search

ARL3

0.93	ADP ribosylation factor like GTPase 3

0.54	GO:0042461	photoreceptor cell development
0.53	GO:0000281	mitotic cytokinesis
0.53	GO:0001822	kidney development
0.53	GO:0060271	cilium assembly
0.52	GO:0042073	intraciliary transport
0.52	GO:0007224	smoothened signaling pathway
0.52	GO:0006892	post-Golgi vesicle-mediated transport
0.51	GO:0007264	small GTPase mediated signal transduction

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008017	microtubule binding
0.47	GO:0003924	GTPase activity
0.34	GO:0046872	metal ion binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.56	GO:0032391	photoreceptor connecting cilium
0.54	GO:0005881	cytoplasmic microtubule
0.54	GO:0030496	midbody
0.54	GO:0005876	spindle microtubule
0.52	GO:0005813	centrosome
0.51	GO:0036064	ciliary basal body
0.51	GO:0005930	axoneme
0.49	GO:0005794	Golgi apparatus
0.44	GO:0005634	nucleus
0.39	GO:0098588	bounding membrane of organelle

sp|P38062|MAP2_RAT
Methionine aminopeptidase 2
Search

METAP2

0.63	Methionine aminopeptidase 2

0.69	GO:0070084	protein initiator methionine removal
0.60	GO:0006508	proteolysis
0.58	GO:0018206	peptidyl-methionine modification
0.53	GO:0031365	N-terminal protein amino acid modification
0.50	GO:0051604	protein maturation
0.41	GO:0060218	hematopoietic stem cell differentiation
0.41	GO:0060216	definitive hemopoiesis
0.39	GO:0016055	Wnt signaling pathway
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0045766	positive regulation of angiogenesis

0.73	GO:0008235	metalloexopeptidase activity
0.71	GO:0004177	aminopeptidase activity
0.53	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:3.4.11

GO:0004177

sp|P38406|GNAL_RAT
Guanine nucleotide-binding protein G(olf) subunit alpha
Search

GNAL

0.79	Guanine nucleotide binding protein, alpha stimulating, olfactory type

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0019933	cAMP-mediated signaling
0.46	GO:0050877	nervous system process
0.43	GO:0043950	positive regulation of cAMP-mediated signaling
0.42	GO:0030819	positive regulation of cAMP biosynthetic process
0.40	GO:0050790	regulation of catalytic activity
0.40	GO:2000828	regulation of parathyroid hormone secretion
0.39	GO:0060789	hair follicle placode formation
0.39	GO:0040032	post-embryonic body morphogenesis
0.39	GO:0044093	positive regulation of molecular function

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.47	GO:0001664	G-protein coupled receptor binding
0.39	GO:0035255	ionotropic glutamate receptor binding
0.39	GO:0051428	peptide hormone receptor binding
0.39	GO:0005159	insulin-like growth factor receptor binding
0.37	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.37	GO:0031681	G-protein beta-subunit binding

0.48	GO:1905360	GTPase complex
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0098797	plasma membrane protein complex
0.38	GO:0070062	extracellular exosome
0.38	GO:0030425	dendrite
0.37	GO:0032588	trans-Golgi network membrane
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0042383	sarcolemma
0.36	GO:0005829	cytosol
0.36	GO:0001726	ruffle

0.37

EC:3.1.4.39

GO:0047391

sp|P38438|TGFR2_RAT
TGF-beta receptor type-2
Search

TGFBR2

0.74	Serine/threonine-protein kinase receptor

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.73	GO:0071560	cellular response to transforming growth factor beta stimulus
0.66	GO:0023014	signal transduction by protein phosphorylation
0.63	GO:0006915	apoptotic process
0.61	GO:0040008	regulation of growth
0.59	GO:0030154	cell differentiation
0.57	GO:1905317	inferior endocardial cushion morphogenesis
0.57	GO:0002651	positive regulation of tolerance induction to self antigen
0.57	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation
0.56	GO:0060434	bronchus morphogenesis

0.86	GO:0005026	transforming growth factor beta receptor activity, type II
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.56	GO:0034713	type I transforming growth factor beta receptor binding
0.56	GO:0050431	transforming growth factor beta binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.53	GO:0046332	SMAD binding

0.69	GO:0043235	receptor complex
0.52	GO:0005901	caveola
0.51	GO:0009897	external side of plasma membrane
0.37	GO:1902554	serine/threonine protein kinase complex
0.35	GO:0005829	cytosol
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0031012	extracellular matrix

0.79

GO:0004702

sp|P38444|AVR2A_RAT
Activin receptor type-2A
Search

ACVR2A

0.74	Serine/threonine-protein kinase receptor

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.59	GO:0043084	penile erection
0.59	GO:0032927	positive regulation of activin receptor signaling pathway
0.59	GO:0042713	sperm ejaculation
0.58	GO:0060011	Sertoli cell proliferation
0.58	GO:0045648	positive regulation of erythrocyte differentiation
0.57	GO:0030501	positive regulation of bone mineralization
0.57	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.57	GO:0045669	positive regulation of osteoblast differentiation

0.81	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.59	GO:0048185	activin binding
0.59	GO:0034711	inhibin binding
0.57	GO:0015026	coreceptor activity
0.55	GO:0043621	protein self-association
0.55	GO:0030165	PDZ domain binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0034673	inhibin-betaglycan-ActRII complex
0.54	GO:0043235	receptor complex
0.51	GO:0009986	cell surface
0.39	GO:0005737	cytoplasm
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:1902554	serine/threonine protein kinase complex

0.81

GO:0004675

sp|P38445|AVR2B_RAT
Activin receptor type-2B
Search

ACVR2B

0.74	Serine/threonine-protein kinase receptor

0.79	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.54	GO:0032927	positive regulation of activin receptor signaling pathway
0.54	GO:0060836	lymphatic endothelial cell differentiation
0.54	GO:0048617	embryonic foregut morphogenesis
0.53	GO:0061298	retina vasculature development in camera-type eye
0.53	GO:0060841	venous blood vessel development
0.53	GO:0030501	positive regulation of bone mineralization
0.53	GO:0001946	lymphangiogenesis
0.53	GO:0045669	positive regulation of osteoblast differentiation

0.81	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0048185	activin binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.51	GO:0019838	growth factor binding
0.50	GO:0004712	protein serine/threonine/tyrosine kinase activity

0.49	GO:0043235	receptor complex
0.42	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm
0.36	GO:0045178	basal part of cell
0.35	GO:0005886	plasma membrane
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.81

GO:0004675

sp|P38483|ABEC1_RAT
C->U-editing enzyme APOBEC-1
Search

APOBEC1

0.96	Apolipoprotein B mRNA editing enzyme catalytic subunit 1

0.69	GO:0090310	negative regulation of methylation-dependent chromatin silencing
0.66	GO:0090209	negative regulation of triglyceride metabolic process
0.64	GO:0016554	cytidine to uridine editing
0.64	GO:0080111	DNA demethylation
0.63	GO:0048255	mRNA stabilization
0.62	GO:0010332	response to gamma radiation
0.59	GO:0006641	triglyceride metabolic process
0.58	GO:0016556	mRNA modification
0.58	GO:0042953	lipoprotein transport
0.56	GO:0042127	regulation of cell proliferation

0.71	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.63	GO:0008270	zinc ion binding
0.63	GO:0017091	AU-rich element binding
0.44	GO:0019904	protein domain specific binding
0.44	GO:0003729	mRNA binding
0.43	GO:0008047	enzyme activator activity
0.43	GO:0043021	ribonucleoprotein complex binding
0.43	GO:0019239	deaminase activity
0.35	GO:0008083	growth factor activity

0.42	GO:0005737	cytoplasm
0.40	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005576	extracellular region
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:3.5.4

GO:0016814

sp|P38552|LEG4_RAT
Galectin-4
Search

LGALS4

0.61

Galectin

0.39	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation
0.39	GO:2001181	positive regulation of interleukin-10 secretion
0.39	GO:0070241	positive regulation of activated T cell autonomous cell death
0.38	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.38	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.38	GO:0043301	negative regulation of leukocyte degranulation
0.38	GO:0045591	positive regulation of regulatory T cell differentiation
0.38	GO:1902713	regulation of interferon-gamma secretion
0.38	GO:0002519	natural killer cell tolerance induction
0.38	GO:2000778	positive regulation of interleukin-6 secretion

0.70	GO:0030246	carbohydrate binding
0.64	GO:0016936	galactoside binding
0.36	GO:0005515	protein binding
0.35	GO:0043539	protein serine/threonine kinase activator activity
0.33	GO:0004871	signal transducer activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0036094	small molecule binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.53	GO:0005615	extracellular space
0.38	GO:0005829	cytosol
0.35	GO:1903561	extracellular vesicle
0.34	GO:0005634	nucleus

0.35

GO:0051353

sp|P38650|DYHC1_RAT
Cytoplasmic dynein 1 heavy chain 1
Search

DYNC1H1

0.85	Dynein heavy chain, cytoplasmic

0.72	GO:0007018	microtubule-based movement
0.52	GO:1905832	positive regulation of spindle assembly
0.51	GO:0090235	regulation of metaphase plate congression
0.51	GO:0033962	cytoplasmic mRNA processing body assembly
0.50	GO:0034063	stress granule assembly
0.49	GO:0060236	regulation of mitotic spindle organization
0.49	GO:0051293	establishment of spindle localization
0.49	GO:0032388	positive regulation of intracellular transport
0.47	GO:0099518	vesicle cytoskeletal trafficking
0.47	GO:0031122	cytoplasmic microtubule organization

0.73	GO:0003777	microtubule motor activity
0.59	GO:0016887	ATPase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0051959	dynein light intermediate chain binding
0.48	GO:0045503	dynein light chain binding
0.47	GO:0045505	dynein intermediate chain binding
0.34	GO:0003723	RNA binding

0.74	GO:0030286	dynein complex
0.49	GO:0030175	filopodium
0.47	GO:0005813	centrosome
0.45	GO:0005874	microtubule
0.38	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.36	GO:0002177	manchette
0.36	GO:0031983	vesicle lumen
0.36	GO:0012505	endomembrane system

0.59

GO:0016887

sp|P38652|PGM1_RAT
Phosphoglucomutase-1
Search

PGM1

0.83	Phosphoglucomutase-1

0.60	GO:0005975	carbohydrate metabolic process
0.43	GO:0006112	energy reserve metabolic process
0.41	GO:0044282	small molecule catabolic process
0.40	GO:1901575	organic substance catabolic process
0.37	GO:0009059	macromolecule biosynthetic process
0.36	GO:0071259	cellular response to magnetism
0.36	GO:0044260	cellular macromolecule metabolic process
0.36	GO:0044249	cellular biosynthetic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006874	cellular calcium ion homeostasis

0.74	GO:0016868	intramolecular transferase activity, phosphotransferases
0.64	GO:0000287	magnesium ion binding
0.39	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.47	GO:0015629	actin cytoskeleton
0.42	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0016529	sarcoplasmic reticulum
0.35	GO:0030018	Z disc
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:5.4.2

GO:0016868

sp|P38656|LA_RAT
Lupus La protein homolog
Search

SSB

0.90	Sjogren syndrome antigen B

0.76	GO:0071045	nuclear histone mRNA catabolic process
0.73	GO:1903608	protein localization to cytoplasmic stress granule
0.73	GO:0075522	IRES-dependent viral translational initiation
0.71	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.70	GO:0051031	tRNA transport
0.69	GO:0097064	ncRNA export from nucleus
0.64	GO:0001682	tRNA 5'-leader removal
0.64	GO:0042780	tRNA 3'-end processing

0.73	GO:1990825	sequence-specific mRNA binding
0.70	GO:0008266	poly(U) RNA binding
0.57	GO:0000049	tRNA binding

0.61	GO:0005634	nucleus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0005737	cytoplasm

sp|P38659|PDIA4_RAT
Protein disulfide-isomerase A4
Search

PDIA4

0.83	Protein disulfide-isomerase A4

0.69	GO:0045454	cell redox homeostasis
0.52	GO:0034976	response to endoplasmic reticulum stress
0.47	GO:0006457	protein folding
0.39	GO:0055114	oxidation-reduction process
0.30	GO:1903334	positive regulation of protein folding

0.81	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds
0.57	GO:0140096	catalytic activity, acting on a protein
0.51	GO:0015037	peptide disulfide oxidoreductase activity
0.30	GO:0005515	protein binding
0.30	GO:0003676	nucleic acid binding

0.81	GO:0005788	endoplasmic reticulum lumen
0.48	GO:0009986	cell surface
0.47	GO:0005615	extracellular space
0.30	GO:0032991	macromolecular complex
0.30	GO:0048770	pigment granule
0.30	GO:0005790	smooth endoplasmic reticulum

0.81

EC:5.3.4

GO:0016864

sp|P38718|MPC2_RAT
Mitochondrial pyruvate carrier 2
Search

MPC2

0.61	Mitochondrial pyruvate carrier

0.84	GO:0006850	mitochondrial pyruvate transmembrane transport
0.57	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate
0.54	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus

0.58

GO:0050833

pyruvate transmembrane transporter activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.46	GO:0031301	integral component of organelle membrane
0.34	GO:0005634	nucleus

sp|P38918|ARK73_RAT
Aflatoxin B1 aldehyde reductase member 3
Search

AKR7A2

0.86	Aflatoxin B1 aldehyde reductase member 3

0.53	GO:0044598	doxorubicin metabolic process
0.53	GO:0044597	daunorubicin metabolic process
0.49	GO:0055114	oxidation-reduction process
0.40	GO:0006805	xenobiotic metabolic process
0.39	GO:0046223	aflatoxin catabolic process
0.37	GO:0006081	cellular aldehyde metabolic process
0.35	GO:0006091	generation of precursor metabolites and energy
0.34	GO:0005975	carbohydrate metabolic process

0.55	GO:0019119	phenanthrene-9,10-epoxide hydrolase activity
0.50	GO:0016491	oxidoreductase activity
0.40	GO:0042802	identical protein binding

0.46	GO:0005829	cytosol
0.45	GO:0005739	mitochondrion
0.44	GO:0070062	extracellular exosome
0.39	GO:0005794	Golgi apparatus
0.35	GO:0031984	organelle subcompartment

0.55

EC:3.3.2

GO:0019119

sp|P38983|RSSA_RAT
40S ribosomal protein SA
Search

RPSA

0.72	40S ribosomal protein SA

0.77	GO:0000028	ribosomal small subunit assembly
0.66	GO:0007155	cell adhesion
0.58	GO:0006518	peptide metabolic process
0.58	GO:0043604	amide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:1901566	organonitrogen compound biosynthetic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.47	GO:0006407	rRNA export from nucleus
0.42	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.85	GO:0005055	laminin receptor activity
0.79	GO:0043236	laminin binding
0.62	GO:0003735	structural constituent of ribosome
0.38	GO:0104005	hijacked molecular function
0.36	GO:0043022	ribosome binding
0.33	GO:0003723	RNA binding

0.74	GO:0022627	cytosolic small ribosomal subunit
0.58	GO:0005634	nucleus
0.53	GO:0005886	plasma membrane
0.45	GO:0030686	90S preribosome
0.37	GO:0005604	basement membrane
0.37	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.33	GO:0043233	organelle lumen

sp|P39020|MEOX2_RAT
Homeobox protein MOX-2
Search

MEOX2

0.97	Homeobox protein MOX-2

0.67	GO:0001757	somite specification
0.63	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.62	GO:0070997	neuron death
0.61	GO:0060021	palate development
0.59	GO:0007519	skeletal muscle tissue development
0.59	GO:0060173	limb development
0.59	GO:0006366	transcription by RNA polymerase II
0.58	GO:0001525	angiogenesis
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0061056	sclerotome development

0.63	GO:0043565	sequence-specific DNA binding
0.63	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.63	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0035326	enhancer binding
0.59	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.45	GO:0071837	HMG box domain binding
0.44	GO:0001047	core promoter binding
0.44	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

sp|P39032|RL36_RAT
60S ribosomal protein L36
Search

RPL36

0.70	60S ribosomal protein L36 pseudogene

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.43	GO:0007420	brain development
0.41	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0070840	dynein complex binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0008134	transcription factor binding
0.32	GO:0016491	oxidoreductase activity

0.60	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.45	GO:0005844	polysome
0.43	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

sp|P39052|DYN2_RAT
Dynamin-2
Search

DNM2

0.94	Putative vacuolar sorting protein vps1 dynamin

0.71	GO:0006897	endocytosis
0.55	GO:1903526	negative regulation of membrane tubulation
0.53	GO:0033572	transferrin transport
0.53	GO:0060976	coronary vasculature development
0.53	GO:0035904	aorta development
0.52	GO:0003281	ventricular septum development
0.50	GO:0043112	receptor metabolic process
0.48	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.46	GO:0000266	mitochondrial fission
0.43	GO:0060026	convergent extension

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.49	GO:0017124	SH3 domain binding
0.43	GO:0008017	microtubule binding
0.40	GO:0031749	D2 dopamine receptor binding
0.39	GO:0050998	nitric-oxide synthase binding
0.39	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.39	GO:0050699	WW domain binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0032403	protein complex binding

0.73	GO:0005874	microtubule
0.53	GO:0001917	photoreceptor inner segment
0.50	GO:0045211	postsynaptic membrane
0.46	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.40	GO:0030670	phagocytic vesicle membrane
0.40	GO:0001891	phagocytic cup
0.39	GO:0031966	mitochondrial membrane
0.39	GO:0030426	growth cone
0.39	GO:0014069	postsynaptic density

sp|P39069|KAD1_RAT
Adenylate kinase isoenzyme 1
Search

AK1

0.91	Adenylate kinase isoenzyme 1

0.76	GO:0006172	ADP biosynthetic process
0.66	GO:0046033	AMP metabolic process
0.66	GO:0046939	nucleotide phosphorylation
0.64	GO:0009142	nucleoside triphosphate biosynthetic process
0.60	GO:0046034	ATP metabolic process
0.51	GO:0007050	cell cycle arrest
0.37	GO:0097503	sialylation
0.37	GO:0033993	response to lipid
0.36	GO:0015949	nucleobase-containing small molecule interconversion
0.36	GO:0006486	protein glycosylation

0.74	GO:0004017	adenylate kinase activity
0.73	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008373	sialyltransferase activity
0.36	GO:0019206	nucleoside kinase activity
0.35	GO:0030695	GTPase regulator activity

0.53	GO:0001520	outer dense fiber
0.48	GO:0005829	cytosol
0.41	GO:0005815	microtubule organizing center
0.40	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0030017	sarcomere
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.74

EC:2.7.4.3

GO:0004017

sp|P39878|PA2GC_RAT
Group IIC secretory phospholipase A2
Search

PLA2G2C

0.65	Group IIC secretory phospholipase A2

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.47	GO:0042130	negative regulation of T cell proliferation
0.36	GO:0051173	positive regulation of nitrogen compound metabolic process
0.36	GO:0010604	positive regulation of macromolecule metabolic process
0.36	GO:0031325	positive regulation of cellular metabolic process
0.36	GO:0032501	multicellular organismal process
0.36	GO:0046486	glycerolipid metabolic process
0.36	GO:0090238	positive regulation of arachidonic acid secretion

0.84	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.84	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.82	GO:0004623	phospholipase A2 activity
0.70	GO:0005509	calcium ion binding
0.36	GO:0090729	toxin activity
0.34	GO:0005543	phospholipid binding
0.34	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0005102	receptor binding
0.34	GO:0008201	heparin binding
0.33	GO:0015446	ATPase-coupled arsenite transmembrane transporter activity

0.66	GO:0005576	extracellular region
0.34	GO:0005829	cytosol
0.34	GO:0009986	cell surface
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.82

EC:3.1.1.4

GO:0004623

sp|P39947|CCNC_RAT
Cyclin-C
Search

CCNC

0.90

Cyclin-C

0.76	GO:0045859	regulation of protein kinase activity
0.49	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.47	GO:0072015	glomerular visceral epithelial cell development
0.46	GO:0045787	positive regulation of cell cycle
0.46	GO:0033674	positive regulation of kinase activity
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0090209	negative regulation of triglyceride metabolic process
0.34	GO:0016567	protein ubiquitination
0.33	GO:0016310	phosphorylation

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0016301	kinase activity
0.33	GO:0005515	protein binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.77	GO:0016592	mediator complex
0.47	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.34	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

0.82

GO:0016538

sp|P39948|CCND1_RAT
G1/S-specific cyclin-D1
Search

CCND1

0.97	G1/S-specific cyclin-D1

0.67	GO:0007049	cell cycle
0.58	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.58	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.57	GO:1901992	positive regulation of mitotic cell cycle phase transition
0.57	GO:0070141	response to UV-A
0.56	GO:0044783	G1 DNA damage checkpoint
0.56	GO:0071157	negative regulation of cell cycle arrest
0.55	GO:1902807	negative regulation of cell cycle G1/S phase transition
0.55	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.55	GO:0097421	liver regeneration

0.54	GO:0070064	proline-rich region binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0003714	transcription corepressor activity
0.53	GO:0042826	histone deacetylase binding
0.51	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.48	GO:0008134	transcription factor binding
0.44	GO:0004672	protein kinase activity
0.39	GO:0032403	protein complex binding
0.35	GO:0060089	molecular transducer activity

0.61	GO:0005634	nucleus
0.58	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.53	GO:0017053	transcriptional repressor complex
0.51	GO:0005923	bicellular tight junction
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.41	GO:0005829	cytosol
0.40	GO:0005694	chromosome
0.40	GO:0012505	endomembrane system
0.38	GO:0031090	organelle membrane

0.51

GO:0016538

sp|P39949|CCNE1_RAT
G1/S-specific cyclin-E1
Search

CCNE1

0.91

Cyclin E

0.83	GO:0000082	G1/S transition of mitotic cell cycle
0.73	GO:0051726	regulation of cell cycle
0.57	GO:0007129	synapsis
0.54	GO:0000723	telomere maintenance
0.53	GO:1903827	regulation of cellular protein localization
0.53	GO:0045859	regulation of protein kinase activity
0.53	GO:0006270	DNA replication initiation
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0016055	Wnt signaling pathway
0.46	GO:0006468	protein phosphorylation

0.56	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.53	GO:0019901	protein kinase binding
0.44	GO:0016301	kinase activity
0.35	GO:0050681	androgen receptor binding
0.34	GO:0032403	protein complex binding
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.60	GO:0097134	cyclin E1-CDK2 complex
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.41	GO:0097135	cyclin E2-CDK2 complex
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0005829	cytosol

0.56

GO:0016538

sp|P39950|CCNG1_RAT
Cyclin-G1
Search

0.73	GO:0051726	regulation of cell cycle
0.38	GO:0051301	cell division
0.38	GO:0007049	cell cycle
0.35	GO:0006949	syncytium formation
0.35	GO:0007420	brain development
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:0010243	response to organonitrogen compound
0.34	GO:0071900	regulation of protein serine/threonine kinase activity
0.33	GO:0006974	cellular response to DNA damage stimulus
0.33	GO:0015991	ATP hydrolysis coupled proton transport

0.33	GO:0005515	protein binding
0.33	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005634	nucleus
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P39951|CDK1_RAT
Cyclin-dependent kinase 1
Search

CDK1

0.87	LOW QUALITY PROTEIN: cyclin-dependent kinase 1

0.63	GO:0006468	protein phosphorylation
0.55	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.53	GO:0051726	regulation of cell cycle
0.53	GO:0044772	mitotic cell cycle phase transition
0.52	GO:0034501	protein localization to kinetochore
0.52	GO:0018210	peptidyl-threonine modification
0.51	GO:1900182	positive regulation of protein localization to nucleus
0.51	GO:0018209	peptidyl-serine modification
0.50	GO:0016570	histone modification
0.50	GO:0030855	epithelial cell differentiation

0.66	GO:0004674	protein serine/threonine kinase activity
0.58	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0035173	histone kinase activity
0.52	GO:0030544	Hsp70 protein binding
0.51	GO:0030332	cyclin binding
0.48	GO:0003682	chromatin binding

0.56	GO:0097125	cyclin B1-CDK1 complex
0.53	GO:0072686	mitotic spindle
0.51	GO:0030496	midbody
0.51	GO:0005876	spindle microtubule
0.50	GO:0005815	microtubule organizing center
0.48	GO:0005759	mitochondrial matrix
0.46	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:0000781	chromosome, telomeric region

0.66

GO:0004674

sp|P40112|PSB3_RAT
Proteasome subunit beta type-3
Search

PSMB3

0.53	Proteasome subunit beta type

0.77	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0070498	interleukin-1-mediated signaling pathway
0.35	GO:0038061	NIK/NF-kappaB signaling

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.81	GO:0019774	proteasome core complex, beta-subunit complex
0.58	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|P40146|ADCY8_RAT
Adenylate cyclase type 8
Search

ADCY8

0.94	LOW QUALITY PROTEIN: adenylate cyclase type 8

0.76	GO:0006171	cAMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.59	GO:0007616	long-term memory
0.50	GO:0006182	cGMP biosynthetic process
0.45	GO:0016199	axon midline choice point recognition
0.44	GO:0031290	retinal ganglion cell axon guidance
0.38	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.37	GO:0034199	activation of protein kinase A activity
0.37	GO:0071377	cellular response to glucagon stimulus
0.37	GO:0003091	renal water homeostasis

0.77	GO:0004016	adenylate cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.50	GO:0004383	guanylate cyclase activity
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.47	GO:0043168	anion binding
0.36	GO:0047485	protein N-terminus binding
0.36	GO:0008022	protein C-terminus binding
0.36	GO:0005516	calmodulin binding

0.54	GO:0005886	plasma membrane
0.52	GO:0008074	guanylate cyclase complex, soluble
0.30	GO:0016021	integral component of membrane

0.77

GO:0004016

sp|P40190|IL6RB_RAT
Interleukin-6 receptor subunit beta
Search

IL6ST

0.96	Interleukin-6 receptor subunit beta

0.76	GO:0019221	cytokine-mediated signaling pathway
0.65	GO:0048861	leukemia inhibitory factor signaling pathway
0.63	GO:0048711	positive regulation of astrocyte differentiation
0.63	GO:0071354	cellular response to interleukin-6
0.62	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.61	GO:0045669	positive regulation of osteoblast differentiation
0.61	GO:0042102	positive regulation of T cell proliferation
0.59	GO:0008593	regulation of Notch signaling pathway
0.54	GO:0005977	glycogen metabolic process
0.42	GO:0070104	negative regulation of interleukin-6-mediated signaling pathway

0.78	GO:0004896	cytokine receptor activity
0.66	GO:0019981	interleukin-6 binding
0.66	GO:0019970	interleukin-11 binding
0.65	GO:0005127	ciliary neurotrophic factor receptor binding
0.63	GO:0005138	interleukin-6 receptor binding
0.36	GO:0046983	protein dimerization activity
0.35	GO:0042802	identical protein binding

0.65	GO:0005900	oncostatin-M receptor complex
0.65	GO:0005896	interleukin-6 receptor complex
0.65	GO:0070110	ciliary neurotrophic factor receptor complex
0.58	GO:0009897	external side of plasma membrane
0.58	GO:0043025	neuronal cell body
0.58	GO:0030425	dendrite
0.38	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.37	GO:0044298	cell body membrane

sp|P40241|CD9_RAT
CD9 antigen
Search

CD9

0.60	Tetraspanin

0.56	GO:0090331	negative regulation of platelet aggregation
0.54	GO:0030913	paranodal junction assembly
0.54	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.54	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.53	GO:0031623	receptor internalization
0.52	GO:0051271	negative regulation of cellular component movement
0.50	GO:0008285	negative regulation of cell proliferation
0.48	GO:0007155	cell adhesion
0.40	GO:0007166	cell surface receptor signaling pathway

0.52	GO:0070062	extracellular exosome
0.51	GO:0009897	external side of plasma membrane
0.39	GO:0005887	integral component of plasma membrane

sp|P40307|PSB2_RAT
Proteasome subunit beta type-2
Search

PSMB2

0.53	Proteasome subunit beta type

0.70	GO:0051603	proteolysis involved in cellular protein catabolic process
0.38	GO:0010243	response to organonitrogen compound
0.38	GO:0014070	response to organic cyclic compound
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.74	GO:0005839	proteasome core complex
0.56	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0005737	cytoplasm
0.43	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P40329|SYRC_RAT
Arginine--tRNA ligase, cytoplasmic
Search

RARS

0.66	Arginyl-tRNA synthetase

0.77	GO:0006420	arginyl-tRNA aminoacylation
0.34	GO:0006364	rRNA processing
0.34	GO:0008033	tRNA processing
0.34	GO:0032259	methylation

0.78	GO:0004814	arginine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0045296	cadherin binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0034618	arginine binding
0.36	GO:0000049	tRNA binding
0.34	GO:0008168	methyltransferase activity

0.58	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.49	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.78

EC:6.1.1.19

GO:0004814

sp|P40615|DKC1_RAT
H/ACA ribonucleoprotein complex subunit 4
Search

DKC1

0.91	Dyskerin pseudouridine synthase 1

0.72	GO:0001522	pseudouridine synthesis
0.67	GO:0090669	telomerase RNA stabilization
0.66	GO:1904851	positive regulation of establishment of protein localization to telomere
0.66	GO:0033979	box H/ACA snoRNA metabolic process
0.65	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.64	GO:0051973	positive regulation of telomerase activity
0.64	GO:0007004	telomere maintenance via telomerase
0.63	GO:0006396	RNA processing
0.61	GO:0032212	positive regulation of telomere maintenance via telomerase
0.55	GO:0016072	rRNA metabolic process

0.72	GO:0009982	pseudouridine synthase activity
0.65	GO:0034513	box H/ACA snoRNA binding
0.65	GO:0070034	telomerase RNA binding
0.63	GO:0003720	telomerase activity

0.66	GO:0090661	box H/ACA telomerase RNP complex
0.64	GO:0031429	box H/ACA snoRNP complex
0.61	GO:0001650	fibrillar center
0.60	GO:0015030	Cajal body
0.39	GO:0019013	viral nucleocapsid

0.72

EC:5.4.99.12

GO:0009982

sp|P40748|SYT3_RAT
Synaptotagmin-3
Search

SYT3

0.78	Synaptotagmin III

0.72	GO:0017156	calcium ion regulated exocytosis
0.70	GO:0017158	regulation of calcium ion-dependent exocytosis
0.61	GO:1903861	positive regulation of dendrite extension
0.60	GO:0050796	regulation of insulin secretion
0.49	GO:0048489	synaptic vesicle transport
0.49	GO:0099504	synaptic vesicle cycle
0.49	GO:0006906	vesicle fusion
0.49	GO:0099643	signal release from synapse
0.49	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.47	GO:0006836	neurotransmitter transport

0.50	GO:0000149	SNARE binding
0.49	GO:0005544	calcium-dependent phospholipid binding
0.48	GO:0030276	clathrin binding
0.45	GO:0005509	calcium ion binding
0.39	GO:0001786	phosphatidylserine binding
0.39	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.37	GO:0042802	identical protein binding
0.30	GO:0046982	protein heterodimerization activity

0.54	GO:0005768	endosome
0.48	GO:0098793	presynapse
0.39	GO:0005886	plasma membrane
0.39	GO:0031045	dense core granule
0.35	GO:0099501	exocytic vesicle membrane
0.35	GO:0030667	secretory granule membrane
0.34	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|P41034|TTPA_RAT
Alpha-tocopherol transfer protein
Search

TTPA

0.72	Gamma-glutamyl hydrolase

0.85	GO:0090212	negative regulation of establishment of blood-brain barrier
0.81	GO:0042360	vitamin E metabolic process
0.75	GO:0120009	intermembrane lipid transfer
0.74	GO:0043009	chordate embryonic development
0.68	GO:0001890	placenta development
0.68	GO:0051180	vitamin transport
0.64	GO:0048568	embryonic organ development
0.61	GO:0009636	response to toxic substance
0.57	GO:0007417	central nervous system development
0.55	GO:0051452	intracellular pH reduction

0.84	GO:0008431	vitamin E binding
0.79	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.76	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.75	GO:0120013	intermembrane lipid transfer activity
0.38	GO:0005515	protein binding
0.37	GO:0034722	gamma-glutamyl-peptidase activity
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.53	GO:0005770	late endosome
0.48	GO:0005829	cytosol
0.35	GO:0005773	vacuole
0.35	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.37

EC:3.4.19.9

GO:0034722

sp|P41123|RL13_RAT
60S ribosomal protein L13
Search

RPL13

0.68	Ribosomal protein L13

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.41	GO:0051726	regulation of cell cycle
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006508	proteolysis
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.36	GO:0004222	metalloendopeptidase activity
0.34	GO:0005515	protein binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.47	GO:0005829	cytosol
0.45	GO:0005730	nucleolus
0.44	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.36

GO:0004222

sp|P41135|ID1_RAT
DNA-binding protein inhibitor ID-1
Search

ID1

0.97	DNA-binding protein inhibitor

0.70	GO:0045892	negative regulation of transcription, DNA-templated
0.60	GO:0090074	negative regulation of protein homodimerization activity
0.60	GO:0060426	lung vasculature development
0.59	GO:0001886	endothelial cell morphogenesis
0.58	GO:0045667	regulation of osteoblast differentiation
0.58	GO:0043392	negative regulation of DNA binding
0.58	GO:0060425	lung morphogenesis
0.58	GO:0032963	collagen metabolic process
0.57	GO:0045596	negative regulation of cell differentiation
0.57	GO:0031648	protein destabilization

0.67	GO:0046983	protein dimerization activity
0.57	GO:0043621	protein self-association
0.45	GO:0003700	DNA binding transcription factor activity
0.45	GO:0003677	DNA binding
0.43	GO:0008134	transcription factor binding
0.41	GO:0047485	protein N-terminus binding
0.40	GO:0070628	proteasome binding
0.40	GO:0008022	protein C-terminus binding
0.39	GO:0042802	identical protein binding
0.35	GO:1901707	leptomycin B binding

0.60	GO:0005634	nucleus
0.50	GO:0005794	Golgi apparatus
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.38	GO:0015630	microtubule cytoskeleton

sp|P41137|ID2_RAT
DNA-binding protein inhibitor ID-2
Search

ID2

0.97	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.59	GO:0061031	endodermal digestive tract morphogenesis
0.57	GO:0045578	negative regulation of B cell differentiation
0.57	GO:0045777	positive regulation of blood pressure
0.57	GO:0003166	bundle of His development
0.57	GO:0048557	embryonic digestive tract morphogenesis
0.57	GO:0090398	cellular senescence
0.57	GO:2000178	negative regulation of neural precursor cell proliferation
0.56	GO:0001966	thigmotaxis
0.56	GO:0071158	positive regulation of cell cycle arrest

0.68	GO:0046983	protein dimerization activity
0.55	GO:0044325	ion channel binding
0.47	GO:0003677	DNA binding
0.39	GO:0043425	bHLH transcription factor binding
0.34	GO:1901707	leptomycin B binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.44	GO:0043234	protein complex
0.34	GO:0000785	chromatin

sp|P41138|ID3_RAT
DNA-binding protein inhibitor ID-3
Search

ID3

0.97	DNA-binding protein inhibitor ID-3-A

0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.65	GO:0072750	cellular response to leptomycin B
0.62	GO:0045667	regulation of osteoblast differentiation
0.62	GO:0045662	negative regulation of myoblast differentiation
0.61	GO:0030903	notochord development
0.61	GO:0048511	rhythmic process
0.60	GO:0030279	negative regulation of ossification
0.60	GO:0001656	metanephros development
0.59	GO:0043433	negative regulation of DNA binding transcription factor activity
0.59	GO:0042476	odontogenesis

0.68	GO:0046983	protein dimerization activity
0.66	GO:1901707	leptomycin B binding
0.56	GO:0008134	transcription factor binding
0.55	GO:0019904	protein domain specific binding
0.47	GO:0003700	DNA binding transcription factor activity
0.45	GO:0003677	DNA binding
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex

0.34

EC:1.8.4 EC:1.8.4.11

GO:0008113

sp|P41156|ETS1_RAT
Protein C-ets-1
Search

ETS1

0.71	ETS proto-oncogene 1, transcription factor

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030578	PML body organization
0.55	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell
0.54	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.54	GO:0045648	positive regulation of erythrocyte differentiation
0.53	GO:0010595	positive regulation of endothelial cell migration
0.52	GO:0043535	regulation of blood vessel endothelial cell migration
0.51	GO:0045765	regulation of angiogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0042802	identical protein binding
0.47	GO:0003690	double-stranded DNA binding
0.40	GO:0035035	histone acetyltransferase binding
0.34	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.33	GO:0042025	host cell nucleus
0.33	GO:0005737	cytoplasm

sp|P41224|TEF_RAT
Thyrotroph embryonic factor
Search

TEF

0.96	Thyrotrophic embryonic factor

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0006366	transcription by RNA polymerase II
0.43	GO:0007275	multicellular organism development
0.40	GO:0071482	cellular response to light stimulus
0.39	GO:0048511	rhythmic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003690	double-stranded DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|P41232|P2RY2_RAT
P2Y purinoceptor 2
Search

P2RY2

0.97	Purinergic receptor P2Y, G-protein coupled, 2

0.85	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.77	GO:0070257	positive regulation of mucus secretion
0.73	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.71	GO:0097746	regulation of blood vessel diameter
0.68	GO:0030321	transepithelial chloride transport
0.51	GO:0071380	cellular response to prostaglandin E stimulus
0.37	GO:0060406	positive regulation of penile erection
0.37	GO:0006873	cellular ion homeostasis
0.36	GO:0032308	positive regulation of prostaglandin secretion
0.36	GO:0071415	cellular response to purine-containing compound

0.85	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.54	GO:0045030	UTP-activated nucleotide receptor activity
0.37	GO:0031686	A1 adenosine receptor binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0019103	pyrimidine nucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0016324	apical plasma membrane
0.35	GO:0005769	early endosome
0.35	GO:0005764	lysosome
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005739	mitochondrion

sp|P41237|CTXN1_RAT
Cortexin-1
Search

CTXN1

0.97	Cortexin-1

0.36

GO:0007417

central nervous system development

0.30

GO:0044425

membrane part

sp|P41243|MATK_RAT
Megakaryocyte-associated tyrosine-protein kinase
Search

MATK

0.59	Megakaryocyte-associated tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.48	GO:0042127	regulation of cell proliferation
0.46	GO:0030154	cell differentiation
0.46	GO:0046777	protein autophosphorylation
0.45	GO:0045087	innate immune response
0.45	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0034334	adherens junction maintenance
0.43	GO:0010669	epithelial structure maintenance
0.43	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.42	GO:0048167	regulation of synaptic plasticity

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005102	receptor binding
0.33	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.32	GO:0008270	zinc ion binding
0.31	GO:0003676	nucleic acid binding

0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0005911	cell-cell junction
0.35	GO:0005856	cytoskeleton
0.34	GO:0005737	cytoplasm
0.32	GO:0005887	integral component of plasma membrane

0.80

GO:0004715

sp|P41244|VEGP2_RAT
Von Ebner gland protein 2
Search

0.69	von Ebner gland protein 2

0.47	GO:0050909	sensory perception of taste
0.45	GO:0001895	retina homeostasis
0.39	GO:0050896	response to stimulus
0.38	GO:0015909	long-chain fatty acid transport
0.37	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0006508	proteolysis

0.51	GO:0036094	small molecule binding
0.49	GO:0031404	chloride ion binding
0.44	GO:0005102	receptor binding
0.42	GO:0043621	protein self-association
0.41	GO:0008270	zinc ion binding
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0004869	cysteine-type endopeptidase inhibitor activity

0.46	GO:0005576	extracellular region
0.41	GO:0031982	vesicle

sp|P41350|CAV1_RAT
Caveolin-1
Search

CAV1

0.82

Caveolin

0.85	GO:0070836	caveola assembly
0.66	GO:0031295	T cell costimulation
0.64	GO:0031623	receptor internalization
0.63	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.62	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation
0.62	GO:1903609	negative regulation of inward rectifier potassium channel activity
0.61	GO:0033484	nitric oxide homeostasis
0.61	GO:0086098	angiotensin-activated signaling pathway involved in heart process
0.61	GO:0060355	positive regulation of cell adhesion molecule production
0.61	GO:0048550	negative regulation of pinocytosis

0.62	GO:0070320	inward rectifier potassium channel inhibitor activity
0.60	GO:0050998	nitric-oxide synthase binding
0.58	GO:0044325	ion channel binding
0.57	GO:0048365	Rac GTPase binding
0.57	GO:0051117	ATPase binding
0.56	GO:0016504	peptidase activator activity
0.55	GO:0032947	protein complex scaffold activity
0.54	GO:0030674	protein binding, bridging
0.54	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.58	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.58	GO:0002080	acrosomal membrane
0.57	GO:0005768	endosome
0.55	GO:0005925	focal adhesion
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005929	cilium
0.52	GO:0005938	cell cortex
0.48	GO:0005887	integral component of plasma membrane

sp|P41413|PCSK5_RAT
Proprotein convertase subtilisin/kexin type 5
Search

PCSK5

0.69	proprotein convertase subtilisin/kexin type 5

0.61	GO:0006508	proteolysis
0.50	GO:0002001	renin secretion into blood stream
0.48	GO:0042089	cytokine biosynthetic process
0.47	GO:0048566	embryonic digestive tract development
0.47	GO:0060976	coronary vasculature development
0.46	GO:0003279	cardiac septum development
0.46	GO:0048706	embryonic skeletal system development
0.46	GO:0035108	limb morphogenesis
0.46	GO:0007368	determination of left/right symmetry
0.46	GO:0030323	respiratory tube development

0.69	GO:0004252	serine-type endopeptidase activity
0.45	GO:0042277	peptide binding
0.33	GO:0005515	protein binding
0.32	GO:0008201	heparin binding

0.45	GO:0030141	secretory granule
0.44	GO:0005794	Golgi apparatus
0.43	GO:0005615	extracellular space
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005783	endoplasmic reticulum
0.32	GO:0009986	cell surface
0.32	GO:0031012	extracellular matrix
0.30	GO:0042995	cell projection
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P41498|PPAC_RAT
Low molecular weight phosphotyrosine protein phosphatase
Search

ACP1

0.61	Low molecular weight phosphotyrosine protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.46	GO:0048793	pronephros development
0.34	GO:0098916	anterograde trans-synaptic signaling

0.85	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity
0.78	GO:0003993	acid phosphatase activity
0.34	GO:0017124	SH3 domain binding

0.50	GO:0042383	sarcolemma
0.49	GO:0009898	cytoplasmic side of plasma membrane
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.78

EC:3.1.3.2

GO:0003993

sp|P41499|PTN11_RAT
Tyrosine-protein phosphatase non-receptor type 11
Search

PTPN11

0.61	Tyrosine-protein phosphatase non-receptor type

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.60	GO:0051463	negative regulation of cortisol secretion
0.60	GO:0060125	negative regulation of growth hormone secretion
0.59	GO:0061582	intestinal epithelial cell migration
0.59	GO:0033277	abortive mitotic cell cycle
0.58	GO:0036302	atrioventricular canal development
0.58	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.58	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.58	GO:0060020	Bergmann glial cell differentiation
0.57	GO:0071364	cellular response to epidermal growth factor stimulus

0.73	GO:0004725	protein tyrosine phosphatase activity
0.57	GO:0005158	insulin receptor binding
0.57	GO:0051428	peptide hormone receptor binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.55	GO:0030971	receptor tyrosine kinase binding
0.53	GO:0050839	cell adhesion molecule binding
0.40	GO:0031748	D1 dopamine receptor binding
0.40	GO:0043274	phospholipase binding
0.39	GO:0043560	insulin receptor substrate binding
0.37	GO:0019904	protein domain specific binding

0.45	GO:0005737	cytoplasm
0.45	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.73	EC:3.1.3.48	GO:0004725
0.36	KEGG:R04545	GO:0046934

sp|P41516|TOP2A_RAT
DNA topoisomerase 2-alpha
Search

TOP2A

0.64	DNA topoisomerase 2-alpha

0.72	GO:0006265	DNA topological change
0.61	GO:0045870	positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.60	GO:0030263	apoptotic chromosome condensation
0.59	GO:1905463	negative regulation of DNA duplex unwinding
0.58	GO:0040016	embryonic cleavage
0.57	GO:0048513	animal organ development
0.55	GO:0030154	cell differentiation
0.55	GO:0042752	regulation of circadian rhythm
0.53	GO:0007059	chromosome segregation
0.53	GO:0043065	positive regulation of apoptotic process

0.74	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity
0.64	GO:0005080	protein kinase C binding
0.63	GO:0042826	histone deacetylase binding
0.62	GO:0008022	protein C-terminus binding
0.58	GO:0003682	chromatin binding
0.56	GO:0046982	protein heterodimerization activity
0.56	GO:0008301	DNA binding, bending
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0043130	ubiquitin binding
0.54	GO:0097367	carbohydrate derivative binding

0.58	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)
0.54	GO:0005814	centriole
0.54	GO:0005654	nucleoplasm
0.53	GO:0005694	chromosome
0.51	GO:0005730	nucleolus
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005829	cytosol
0.36	GO:0019035	viral integration complex
0.31	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.74

EC:5.99.1.3

GO:0003918

sp|P41542|USO1_RAT
General vesicular transport factor p115
Search

USO1

0.92	USO1 vesicle transport factor

0.85	GO:0048280	vesicle fusion with Golgi apparatus
0.69	GO:0006886	intracellular protein transport
0.56	GO:0007030	Golgi organization
0.52	GO:0048211	Golgi vesicle docking
0.52	GO:0045056	transcytosis
0.48	GO:0006888	ER to Golgi vesicle-mediated transport

0.68	GO:0008565	protein transporter activity
0.58	GO:0045296	cadherin binding

0.74	GO:0000139	Golgi membrane
0.59	GO:0001650	fibrillar center
0.55	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005829	cytosol
0.48	GO:0012507	ER to Golgi transport vesicle membrane
0.48	GO:0005795	Golgi stack
0.45	GO:0005783	endoplasmic reticulum
0.36	GO:0070382	exocytic vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P41562|IDHC_RAT
Isocitrate dehydrogenase [NADP] cytoplasmic
Search

IDH1

0.49	Isocitrate dehydrogenase [NADP] cytoplasmic

0.81	GO:0006102	isocitrate metabolic process
0.60	GO:0006099	tricarboxylic acid cycle
0.53	GO:0006103	2-oxoglutarate metabolic process
0.53	GO:0060696	regulation of phospholipid catabolic process
0.51	GO:0071071	regulation of phospholipid biosynthetic process
0.47	GO:0006749	glutathione metabolic process
0.46	GO:0006979	response to oxidative stress
0.42	GO:0048513	animal organ development
0.41	GO:0006097	glyoxylate cycle
0.40	GO:0002520	immune system development

0.78	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.67	GO:0051287	NAD binding
0.64	GO:0000287	magnesium ion binding
0.52	GO:0045296	cadherin binding
0.50	GO:0042803	protein homodimerization activity
0.48	GO:0005102	receptor binding
0.39	GO:0051990	(R)-2-hydroxyglutarate dehydrogenase activity
0.36	GO:0050661	NADP binding

0.50	GO:0005777	peroxisome
0.47	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0031907	microbody lumen

0.78

EC:1.1.1.42

GO:0004450

sp|P41565|IDHG1_RAT
Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial
Search

IDH3G

0.65	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

0.69	GO:0006099	tricarboxylic acid cycle
0.39	GO:0006102	isocitrate metabolic process
0.35	GO:0006734	NADH metabolic process
0.35	GO:0045926	negative regulation of growth
0.35	GO:0006103	2-oxoglutarate metabolic process
0.33	GO:0005975	carbohydrate metabolic process

0.83	GO:0004449	isocitrate dehydrogenase (NAD+) activity
0.67	GO:0051287	NAD binding
0.63	GO:0000287	magnesium ion binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0005739	mitochondrion
0.47	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.35	GO:0045242	isocitrate dehydrogenase complex (NAD+)

0.83

EC:1.1.1.41

GO:0004449

sp|P41682|ADH7_RAT
Alcohol dehydrogenase class 4 mu/sigma chain
Search

ADH7

0.69	Alcohol dehydrogenase class I

0.53	GO:0006068	ethanol catabolic process
0.53	GO:0010430	fatty acid omega-oxidation
0.51	GO:0042573	retinoic acid metabolic process
0.51	GO:0045471	response to ethanol
0.51	GO:0042572	retinol metabolic process
0.50	GO:1900116	extracellular negative regulation of signal transduction
0.50	GO:0006069	ethanol oxidation
0.46	GO:0009617	response to bacterium
0.39	GO:0033574	response to testosterone
0.38	GO:0032526	response to retinoic acid

0.60	GO:0008270	zinc ion binding
0.54	GO:0004024	alcohol dehydrogenase activity, zinc-dependent
0.53	GO:0035276	ethanol binding
0.52	GO:0004745	retinol dehydrogenase activity
0.52	GO:0004031	aldehyde oxidase activity
0.51	GO:0019841	retinol binding
0.50	GO:0048019	receptor antagonist activity
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0051287	NAD binding
0.33	GO:0003735	structural constituent of ribosome

0.45	GO:0005829	cytosol
0.43	GO:0005576	extracellular region
0.40	GO:0005886	plasma membrane
0.37	GO:0005654	nucleoplasm
0.35	GO:0005739	mitochondrion
0.34	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.33	GO:0019866	organelle inner membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.52

GO:0004745

sp|P41738|AHR_RAT
Aryl hydrocarbon receptor
Search

AHR

0.74	Aryl hydrocarbon receptor

0.79	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0009410	response to xenobiotic stimulus
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.55	GO:0014070	response to organic cyclic compound
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:0007623	circadian rhythm
0.48	GO:0030888	regulation of B cell proliferation

0.85	GO:0004874	aryl hydrocarbon receptor activity
0.65	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0070888	E-box binding
0.49	GO:0001094	TFIID-class transcription factor binding
0.49	GO:0001223	transcription coactivator binding
0.48	GO:0051879	Hsp90 protein binding
0.47	GO:0035326	enhancer binding
0.46	GO:0017025	TBP-class protein binding
0.38	GO:0051087	chaperone binding

0.85	GO:0034751	aryl hydrocarbon receptor complex
0.59	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.40	GO:0005737	cytoplasm
0.37	GO:0044446	intracellular organelle part
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

sp|P41739|ARNT_RAT
Aryl hydrocarbon receptor nuclear translocator
Search

ARNT

0.90	Aryl hydrocarbon receptor nuclear translocator

0.61	GO:0033235	positive regulation of protein sumoylation
0.61	GO:0046886	positive regulation of hormone biosynthetic process
0.60	GO:0010575	positive regulation of vascular endothelial growth factor production
0.60	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0001666	response to hypoxia
0.56	GO:0001892	embryonic placenta development
0.56	GO:0030522	intracellular receptor signaling pathway
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0030154	cell differentiation

0.68	GO:0046983	protein dimerization activity
0.65	GO:0017162	aryl hydrocarbon receptor binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0004874	aryl hydrocarbon receptor activity
0.58	GO:0035326	enhancer binding
0.55	GO:0003713	transcription coactivator activity
0.50	GO:0043565	sequence-specific DNA binding
0.45	GO:0001047	core promoter binding
0.43	GO:0003690	double-stranded DNA binding
0.35	GO:0008234	cysteine-type peptidase activity

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0043233	organelle lumen
0.49	GO:0005737	cytoplasm
0.48	GO:0034751	aryl hydrocarbon receptor complex
0.44	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.35

GO:0008234

sp|P41740|ANPRC_RAT
Atrial natriuretic peptide receptor 3
Search

NPR3

0.96	Atrial natriuretic peptide clearance receptor

0.59	GO:0002158	osteoclast proliferation
0.58	GO:0035810	positive regulation of urine volume
0.57	GO:0033688	regulation of osteoblast proliferation
0.54	GO:0008217	regulation of blood pressure
0.53	GO:0001501	skeletal system development
0.45	GO:0007165	signal transduction
0.44	GO:0060038	cardiac muscle cell proliferation
0.42	GO:0030157	pancreatic juice secretion
0.41	GO:0051000	positive regulation of nitric-oxide synthase activity
0.41	GO:0007194	negative regulation of adenylate cyclase activity

0.61	GO:0016941	natriuretic peptide receptor activity
0.58	GO:0031404	chloride ion binding
0.58	GO:0017046	peptide hormone binding
0.52	GO:0042803	protein homodimerization activity
0.39	GO:0008528	G-protein coupled peptide receptor activity

0.44	GO:0043234	protein complex
0.38	GO:0070062	extracellular exosome
0.36	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

sp|P41777|NOLC1_RAT
Nucleolar and coiled-body phosphoprotein 1
Search

NOLC1

0.64	Nucleolar and coiled-body phosphoprotein 1

0.79	GO:0014029	neural crest formation
0.77	GO:0007000	nucleolus organization
0.75	GO:0014032	neural crest cell development
0.64	GO:0006417	regulation of translation
0.46	GO:0048701	embryonic cranial skeleton morphogenesis
0.42	GO:0000451	rRNA 2'-O-methylation
0.37	GO:0033979	box H/ACA snoRNA metabolic process
0.36	GO:0042306	regulation of protein import into nucleus
0.36	GO:0000278	mitotic cell cycle
0.36	GO:0006970	response to osmotic stress

0.80	GO:0001042	RNA polymerase I core binding
0.66	GO:0046982	protein heterodimerization activity
0.40	GO:0016758	transferase activity, transferring hexosyl groups
0.37	GO:0034512	box C/D snoRNA binding
0.37	GO:0034513	box H/ACA snoRNA binding
0.37	GO:0008139	nuclear localization sequence binding
0.37	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0046872	metal ion binding

0.75	GO:0015030	Cajal body
0.74	GO:0001650	fibrillar center
0.37	GO:0031428	box C/D snoRNP complex
0.37	GO:0030532	small nuclear ribonucleoprotein complex
0.37	GO:0031429	box H/ACA snoRNP complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:2.4.1

GO:0016758

sp|P42123|LDHB_RAT
L-lactate dehydrogenase B chain
Search

LDHB

0.54	L-lactate dehydrogenase B chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.37	GO:0019674	NAD metabolic process
0.36	GO:1901615	organic hydroxy compound metabolic process
0.33	GO:0016053	organic acid biosynthetic process
0.32	GO:0006091	generation of precursor metabolites and energy
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0044260	cellular macromolecule metabolic process

0.81	GO:0004459	L-lactate dehydrogenase activity
0.48	GO:0042802	identical protein binding
0.38	GO:0019900	kinase binding
0.36	GO:0051287	NAD binding
0.35	GO:0005212	structural constituent of eye lens
0.34	GO:0004373	glycogen (starch) synthase activity

0.52	GO:0043209	myelin sheath
0.51	GO:0045121	membrane raft
0.48	GO:0005737	cytoplasm
0.41	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P42203|IL13_RAT
Interleukin-13
Search

IL13

0.97	Interleukin 13 (Predicted)

0.74	GO:0006955	immune response
0.70	GO:1903660	negative regulation of complement-dependent cytotoxicity
0.66	GO:0043306	positive regulation of mast cell degranulation
0.66	GO:2000352	negative regulation of endothelial cell apoptotic process
0.66	GO:0043032	positive regulation of macrophage activation
0.64	GO:0002639	positive regulation of immunoglobulin production
0.60	GO:0006954	inflammatory response
0.59	GO:0071345	cellular response to cytokine stimulus
0.49	GO:0010469	regulation of receptor activity
0.46	GO:2000231	positive regulation of pancreatic stellate cell proliferation

0.79	GO:0005126	cytokine receptor binding
0.51	GO:0005125	cytokine activity
0.36	GO:0016887	ATPase activity
0.34	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.61	GO:0009897	external side of plasma membrane
0.41	GO:0005737	cytoplasm
0.40	GO:0030870	Mre11 complex
0.30	GO:0016021	integral component of membrane

0.36

GO:0016887

sp|P42260|GRIK2_RAT
Glutamate receptor ionotropic, kainate 2
Search

GRIK2

0.82	Glutamate ionotropic receptor kainate type subunit 2

0.78	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.56	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.55	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.54	GO:0060080	inhibitory postsynaptic potential
0.54	GO:0050806	positive regulation of synaptic transmission
0.53	GO:0035249	synaptic transmission, glutamatergic
0.53	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.53	GO:0001662	behavioral fear response

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.75	GO:0004970	ionotropic glutamate receptor activity
0.52	GO:0099094	ligand-gated cation channel activity
0.52	GO:0005272	sodium channel activity
0.50	GO:0098782	mechanosensitived potassium channel activity
0.39	GO:0031624	ubiquitin conjugating enzyme binding
0.38	GO:0030165	PDZ domain binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0016595	glutamate binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.55	GO:0032983	kainate selective glutamate receptor complex
0.53	GO:0042734	presynaptic membrane
0.51	GO:0014069	postsynaptic density
0.50	GO:0043025	neuronal cell body
0.40	GO:0030425	dendrite
0.39	GO:0030424	axon
0.39	GO:0043679	axon terminus
0.38	GO:0120111	neuron projection cytoplasm

sp|P42264|GRIK3_RAT
Glutamate receptor ionotropic, kainate 3
Search

GRIK3

0.93	Glutamate ionotropic receptor kainate type subunit 3

0.79	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
0.51	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.50	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.49	GO:0060080	inhibitory postsynaptic potential
0.48	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.48	GO:0001662	behavioral fear response
0.48	GO:0035249	synaptic transmission, glutamatergic

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.57	GO:0099094	ligand-gated cation channel activity
0.57	GO:0005272	sodium channel activity
0.57	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
0.55	GO:0098782	mechanosensitived potassium channel activity
0.38	GO:0031624	ubiquitin conjugating enzyme binding
0.37	GO:0030165	PDZ domain binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0042803	protein homodimerization activity

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.50	GO:0032983	kainate selective glutamate receptor complex
0.48	GO:0042734	presynaptic membrane
0.47	GO:0043025	neuronal cell body
0.47	GO:0014069	postsynaptic density
0.40	GO:0032839	dendrite cytoplasm
0.40	GO:0043195	terminal bouton
0.35	GO:0043197	dendritic spine

sp|P42335|IP3KB_RAT
Inositol-trisphosphate 3-kinase B
Search

ITPKB

0.64	Inositol-trisphosphate 3-kinase B

0.86	GO:0033030	negative regulation of neutrophil apoptotic process
0.85	GO:0035726	common myeloid progenitor cell proliferation
0.85	GO:0045059	positive thymic T cell selection
0.83	GO:0032958	inositol phosphate biosynthetic process
0.82	GO:0046638	positive regulation of alpha-beta T cell differentiation
0.81	GO:0032957	inositol trisphosphate metabolic process
0.81	GO:0071277	cellular response to calcium ion
0.81	GO:0045638	negative regulation of myeloid cell differentiation
0.80	GO:0046579	positive regulation of Ras protein signal transduction
0.79	GO:0002262	myeloid cell homeostasis

0.85	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity
0.74	GO:0005516	calmodulin binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005829	cytosol
0.58	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85	EC:2.7.1.127	GO:0008440
0.85	KEGG:R03433	GO:0008440

sp|P42346|MTOR_RAT
Serine/threonine-protein kinase mTOR
Search

MTOR

0.92	Serine/threonine-protein kinase mTOR

0.71	GO:1903691	positive regulation of wound healing, spreading of epidermal cells
0.70	GO:0051534	negative regulation of NFAT protein import into nucleus
0.70	GO:0050882	voluntary musculoskeletal movement
0.69	GO:0071233	cellular response to leucine
0.69	GO:1990253	cellular response to leucine starvation
0.69	GO:0051549	positive regulation of keratinocyte migration
0.69	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.69	GO:0048714	positive regulation of oligodendrocyte differentiation
0.68	GO:0045792	negative regulation of cell size
0.68	GO:0010592	positive regulation of lamellipodium assembly

0.70	GO:0004674	protein serine/threonine kinase activity
0.70	GO:0044877	macromolecular complex binding
0.70	GO:0001156	TFIIIC-class transcription factor binding
0.69	GO:0001031	RNA polymerase III type 2 promoter DNA binding
0.69	GO:0001030	RNA polymerase III type 1 promoter DNA binding
0.69	GO:0001032	RNA polymerase III type 3 promoter DNA binding
0.65	GO:0051219	phosphoprotein binding
0.58	GO:0042802	identical protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding

0.65	GO:0016605	PML body
0.64	GO:0031931	TORC1 complex
0.63	GO:0031932	TORC2 complex
0.62	GO:0030425	dendrite
0.62	GO:0005764	lysosome
0.55	GO:0005829	cytosol
0.54	GO:0012505	endomembrane system
0.42	GO:0043025	neuronal cell body
0.41	GO:0005741	mitochondrial outer membrane
0.41	GO:0098852	lytic vacuole membrane

0.70

GO:0004674

sp|P42533|TF_RAT
Tissue factor
Search

0.97	Coagulation factor III, tissue factor

0.82	GO:0007596	blood coagulation
0.79	GO:0002541	activation of plasma proteins involved in acute inflammatory response
0.76	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.71	GO:0001938	positive regulation of endothelial cell proliferation
0.71	GO:0051897	positive regulation of protein kinase B signaling
0.71	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.70	GO:0045766	positive regulation of angiogenesis
0.51	GO:0019221	cytokine-mediated signaling pathway
0.42	GO:0030335	positive regulation of cell migration
0.42	GO:0071404	cellular response to low-density lipoprotein particle stimulus

0.68	GO:0002020	protease binding
0.63	GO:0005543	phospholipid binding
0.57	GO:0004252	serine-type endopeptidase activity
0.52	GO:0004896	cytokine receptor activity

0.73	GO:1905286	serine-type peptidase complex
0.64	GO:0009986	cell surface
0.63	GO:0031012	extracellular matrix
0.62	GO:0005615	extracellular space
0.42	GO:1903561	extracellular vesicle
0.41	GO:0005886	plasma membrane
0.36	GO:0098552	side of membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.57

GO:0004252

sp|P42571|PO2F3_RAT
POU domain, class 2, transcription factor 3
Search

POU2F3

0.73	POU domain, class 2, transcription factor 3

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0043922	negative regulation by host of viral transcription
0.57	GO:0006355	regulation of transcription, DNA-templated
0.53	GO:1903508	positive regulation of nucleic acid-templated transcription
0.52	GO:0010628	positive regulation of gene expression
0.47	GO:0002380	immunoglobulin secretion involved in immune response
0.45	GO:0002335	mature B cell differentiation
0.44	GO:0048469	cell maturation
0.39	GO:0008544	epidermis development
0.37	GO:0043588	skin development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.42	GO:0019904	protein domain specific binding
0.35	GO:0046983	protein dimerization activity
0.35	GO:0001047	core promoter binding

0.61	GO:0005634	nucleus
0.40	GO:0043233	organelle lumen
0.38	GO:0005667	transcription factor complex
0.38	GO:0044446	intracellular organelle part
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|P42667|SC11A_RAT
Signal peptidase complex catalytic subunit SEC11A
Search

SEC11A

0.72	Signal peptidase complex catalytic subunit SEC11

0.80

GO:0006465

signal peptide processing

0.67

GO:0008236

serine-type peptidase activity

0.82	GO:0005787	signal peptidase complex
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P42676|NEUL_RAT
Neurolysin, mitochondrial
Search

NLN

0.97	Neurolysin, mitochondrial

0.61	GO:0006508	proteolysis
0.58	GO:1902809	regulation of skeletal muscle fiber differentiation
0.54	GO:0006111	regulation of gluconeogenesis
0.40	GO:0006518	peptide metabolic process
0.33	GO:0035556	intracellular signal transduction

0.70	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.52	GO:0042277	peptide binding
0.36	GO:0070012	oligopeptidase activity

0.47	GO:0005758	mitochondrial intermembrane space
0.41	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|P42854|REG3G_RAT
Regenerating islet-derived protein 3-gamma
Search

0.97	Pancreatic beta cell growth factor

0.68	GO:0044278	cell wall disruption in other organism
0.64	GO:0045617	negative regulation of keratinocyte differentiation
0.63	GO:0010838	positive regulation of keratinocyte proliferation
0.63	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.61	GO:0090303	positive regulation of wound healing
0.60	GO:0050830	defense response to Gram-positive bacterium
0.60	GO:0051715	cytolysis in other organism
0.58	GO:0006953	acute-phase response
0.58	GO:0050829	defense response to Gram-negative bacterium
0.52	GO:0002755	MyD88-dependent toll-like receptor signaling pathway

0.63	GO:0070492	oligosaccharide binding
0.59	GO:0005539	glycosaminoglycan binding
0.51	GO:0042802	identical protein binding
0.48	GO:2001065	mannan binding
0.43	GO:0008083	growth factor activity
0.41	GO:1901681	sulfur compound binding
0.39	GO:0019838	growth factor binding
0.38	GO:0019903	protein phosphatase binding
0.36	GO:0043168	anion binding
0.36	GO:0046983	protein dimerization activity

0.52	GO:0005576	extracellular region
0.52	GO:0030141	secretory granule
0.43	GO:0044216	other organism cell
0.39	GO:0045177	apical part of cell
0.38	GO:0032809	neuronal cell body membrane
0.38	GO:0032590	dendrite membrane
0.38	GO:0045178	basal part of cell
0.38	GO:0030426	growth cone
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0043234	protein complex

0.35	EC:2.3.3.10	GO:0004421
0.35	KEGG:R01978	GO:0004421

sp|P42893|ECE1_RAT
Endothelin-converting enzyme 1
Search

ECE1

0.76	Endothelin converting enzyme

0.85	GO:0016486	peptide hormone processing
0.57	GO:0010814	substance P catabolic process
0.57	GO:0010816	calcitonin catabolic process
0.56	GO:0010815	bradykinin catabolic process
0.55	GO:0001921	positive regulation of receptor recycling
0.54	GO:0060037	pharyngeal system development
0.54	GO:0002002	regulation of angiotensin levels in blood
0.53	GO:0042733	embryonic digit morphogenesis
0.51	GO:0043583	ear development
0.50	GO:0007507	heart development

0.70	GO:0004222	metalloendopeptidase activity
0.49	GO:0042803	protein homodimerization activity
0.43	GO:0008270	zinc ion binding
0.35	GO:0017046	peptide hormone binding
0.34	GO:0000339	RNA cap binding
0.33	GO:0003743	translation initiation factor activity

0.55	GO:0033093	Weibel-Palade body
0.51	GO:0009897	external side of plasma membrane
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005768	endosome
0.37	GO:0044433	cytoplasmic vesicle part
0.37	GO:0012506	vesicle membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0031300	intrinsic component of organelle membrane
0.34	GO:0005794	Golgi apparatus

0.70

GO:0004222

sp|P42930|HSPB1_RAT
Heat shock protein beta-1
Search

HSPB1

0.90	LOW QUALITY PROTEIN: heat shock protein beta-1

0.85	GO:0099641	anterograde axonal protein transport
0.82	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
0.81	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.79	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.79	GO:0032731	positive regulation of interleukin-1 beta production
0.76	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.74	GO:0045766	positive regulation of angiogenesis
0.73	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.73	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.72	GO:0061077	chaperone-mediated protein folding

0.84	GO:0008426	protein kinase C inhibitor activity
0.79	GO:0044183	protein binding involved in protein folding
0.78	GO:0005080	protein kinase C binding
0.69	GO:0042803	protein homodimerization activity
0.45	GO:0043130	ubiquitin binding
0.40	GO:0005212	structural constituent of eye lens
0.37	GO:0003723	RNA binding
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0046872	metal ion binding

0.78	GO:1904115	axon cytoplasm
0.75	GO:0030018	Z disc
0.61	GO:0005634	nucleus
0.51	GO:0005886	plasma membrane
0.51	GO:0005819	spindle
0.43	GO:0031012	extracellular matrix
0.42	GO:1905369	endopeptidase complex
0.42	GO:0005925	focal adhesion
0.42	GO:0070062	extracellular exosome
0.41	GO:0097512	cardiac myofibril

0.35

EC:3.1.4.17

GO:0004114

sp|P43114|PE2R4_RAT
Prostaglandin E2 receptor EP4 subtype
Search

PTGER4

0.93	Prostaglandin E receptor 4

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:2000419	regulation of eosinophil extravasation
0.63	GO:2000417	negative regulation of eosinophil migration
0.62	GO:0033624	negative regulation of integrin activation
0.61	GO:0002692	negative regulation of cellular extravasation
0.58	GO:0050728	negative regulation of inflammatory response
0.58	GO:0042093	T-helper cell differentiation
0.57	GO:0050710	negative regulation of cytokine secretion
0.57	GO:0071260	cellular response to mechanical stimulus
0.56	GO:0050715	positive regulation of cytokine secretion

0.85	GO:0004957	prostaglandin E receptor activity
0.33	GO:0005515	protein binding

0.36	GO:0005886	plasma membrane
0.36	GO:0044306	neuron projection terminus
0.35	GO:0043025	neuronal cell body
0.35	GO:0031965	nuclear membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P43118|PF2R_RAT
Prostaglandin F2-alpha receptor
Search

PTGFR

0.97	Ovarian prostaglandin F receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0071798	response to prostaglandin D
0.62	GO:0071379	cellular response to prostaglandin stimulus
0.61	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.60	GO:0032355	response to estradiol
0.58	GO:0032496	response to lipopolysaccharide
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0043066	negative regulation of apoptotic process
0.52	GO:0010628	positive regulation of gene expression
0.36	GO:0007567	parturition

0.85	GO:0004958	prostaglandin F receptor activity
0.54	GO:0004960	thromboxane receptor activity
0.51	GO:0004957	prostaglandin E receptor activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.49	GO:0005576	extracellular region
0.44	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

EC:1.2.1

GO:0016620

sp|P43138|APEX1_RAT
DNA-(apurinic or apyrimidinic site) lyase
Search

APEX1

0.65	DNA-(apurinic or apyrimidinic site) lyase

0.64	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.56	GO:0043247	telomere maintenance in response to DNA damage
0.56	GO:0080111	DNA demethylation
0.55	GO:0043488	regulation of mRNA stability
0.51	GO:0042981	regulation of apoptotic process
0.48	GO:0045454	cell redox homeostasis
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:0014912	negative regulation of smooth muscle cell migration
0.42	GO:0071320	cellular response to cAMP

0.77	GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) lyase activity
0.77	GO:0140078	class I DNA-(apurinic or apyrimidinic site) lyase activity
0.65	GO:0004519	endonuclease activity
0.58	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.56	GO:0003691	double-stranded telomeric DNA binding
0.55	GO:0031490	chromatin DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:0003713	transcription coactivator activity
0.51	GO:0008408	3'-5' exonuclease activity
0.50	GO:0003684	damaged DNA binding

0.58	GO:0005634	nucleus
0.58	GO:0005739	mitochondrion
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005813	centrosome
0.48	GO:0031974	membrane-enclosed lumen
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0005667	transcription factor complex
0.35	GO:0000781	chromosome, telomeric region
0.33	GO:0005840	ribosome

0.49

EC:3.1.4

GO:0008081

sp|P43140|ADA1A_RAT
Alpha-1A adrenergic receptor
Search

ADRA1A

0.93	Alpha-1a adrenoceptor transcript variant 1

0.85	GO:0071875	adrenergic receptor signaling pathway
0.79	GO:0055117	regulation of cardiac muscle contraction
0.79	GO:0019229	regulation of vasoconstriction
0.70	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
0.67	GO:0045987	positive regulation of smooth muscle contraction
0.66	GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
0.65	GO:1903524	positive regulation of blood circulation
0.65	GO:1903995	regulation of non-membrane spanning protein tyrosine kinase activity
0.65	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.64	GO:0003057	regulation of the force of heart contraction by chemical signal

0.85	GO:0004935	adrenergic receptor activity
0.58	GO:0046982	protein heterodimerization activity

0.61	GO:0031965	nuclear membrane
0.56	GO:0005886	plasma membrane
0.42	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P43143|ACHA6_RAT
Neuronal acetylcholine receptor subunit alpha-6
Search

CHRNA6

0.91	Neuronal acetylcholine receptor subunit alpha-6

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.53	GO:0035094	response to nicotine
0.53	GO:0007274	neuromuscular synaptic transmission
0.49	GO:0007271	synaptic transmission, cholinergic
0.46	GO:0014059	regulation of dopamine secretion
0.46	GO:0051899	membrane depolarization
0.45	GO:0060073	micturition
0.43	GO:0030534	adult behavior
0.41	GO:0007399	nervous system development

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.50	GO:0042166	acetylcholine binding
0.37	GO:0022850	serotonin-gated cation-selective channel activity
0.34	GO:0005515	protein binding
0.33	GO:0051537	2 iron, 2 sulfur cluster binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.54	GO:0005892	acetylcholine-gated channel complex

sp|P43144|ACHA9_RAT
Neuronal acetylcholine receptor subunit alpha-9
Search

CHRNA9

0.97	LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-9

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.57	GO:0042472	inner ear morphogenesis
0.56	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.45	GO:0006812	cation transport
0.33	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.38	GO:0005262	calcium channel activity
0.35	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.58	GO:0005892	acetylcholine-gated channel complex

sp|P43145|ADML_RAT
ADM
Search

ADM

0.97	Adrenomedullin

0.76	GO:0010469	regulation of receptor activity
0.67	GO:1990410	adrenomedullin receptor signaling pathway
0.67	GO:0097647	amylin receptor signaling pathway
0.67	GO:0045906	negative regulation of vasoconstriction
0.66	GO:0002031	G-protein coupled receptor internalization
0.66	GO:0035809	regulation of urine volume
0.65	GO:2001214	positive regulation of vasculogenesis
0.65	GO:0097084	vascular smooth muscle cell development
0.65	GO:0010460	positive regulation of heart rate
0.65	GO:0043116	negative regulation of vascular permeability

0.79	GO:0005179	hormone activity
0.69	GO:0031700	adrenomedullin receptor binding

0.66	GO:0005576	extracellular region
0.41	GO:0005737	cytoplasm

sp|P43165|CAH5A_RAT
Carbonic anhydrase 5A, mitochondrial
Search

CA5A

0.97	Carbonic anhydrase VB, mitochondrial

0.72	GO:0006730	one-carbon metabolic process
0.44	GO:2000021	regulation of ion homeostasis
0.43	GO:2001225	regulation of chloride transport
0.43	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.43	GO:0006885	regulation of pH
0.41	GO:0032846	positive regulation of homeostatic process
0.41	GO:0030004	cellular monovalent inorganic cation homeostasis
0.41	GO:0015670	carbon dioxide transport
0.39	GO:0042539	hypotonic salinity response
0.38	GO:0097369	sodium ion import

0.77	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding
0.36	GO:0004064	arylesterase activity

0.54	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.36	GO:0045177	apical part of cell
0.35	GO:0043209	myelin sheath
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005886	plasma membrane
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:4.2.1.1

GO:0004089

sp|P43219|GIPR_RAT
Gastric inhibitory polypeptide receptor
Search

GIPR

0.97	Gastric inhibitory polypeptide receptor

0.87	GO:0038192	gastric inhibitory peptide signaling pathway
0.71	GO:0007166	cell surface receptor signaling pathway
0.69	GO:0031018	endocrine pancreas development
0.47	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway
0.47	GO:0043950	positive regulation of cAMP-mediated signaling
0.46	GO:0048678	response to axon injury
0.46	GO:0070542	response to fatty acid
0.46	GO:0032024	positive regulation of insulin secretion
0.46	GO:0051592	response to calcium ion
0.46	GO:0009749	response to glucose

0.87	GO:0016519	gastric inhibitory peptide receptor activity
0.46	GO:0017046	peptide hormone binding
0.37	GO:0004967	glucagon receptor activity
0.35	GO:0005515	protein binding

0.53	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P43244|MATR3_RAT
Matrin-3
Search

MATR3

0.91	Nuclear protein matrin 3

0.44	GO:0003170	heart valve development
0.44	GO:0003281	ventricular septum development
0.38	GO:0002218	activation of innate immune response
0.38	GO:0045087	innate immune response
0.37	GO:0010608	posttranscriptional regulation of gene expression

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.37	GO:0042802	identical protein binding
0.33	GO:0005198	structural molecule activity

0.58	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0012505	endomembrane system
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.32	GO:0005737	cytoplasm

sp|P43245|MDR1_RAT
Multidrug resistance protein 1
Search

ABCB1

0.48	Multi-drug resistance P-glycoprotein 1

0.65	GO:0099040	ceramide translocation
0.63	GO:1901529	positive regulation of anion channel activity
0.62	GO:2001225	regulation of chloride transport
0.60	GO:0047484	regulation of response to osmotic stress
0.59	GO:0000086	G2/M transition of mitotic cell cycle
0.59	GO:0072089	stem cell proliferation
0.56	GO:0045332	phospholipid translocation
0.55	GO:0055085	transmembrane transport
0.39	GO:0042908	xenobiotic transport
0.37	GO:0015893	drug transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.65	GO:0099038	ceramide-translocating ATPase activity
0.64	GO:0090555	phosphatidylethanolamine-translocating ATPase activity
0.63	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0015238	drug transmembrane transporter activity
0.35	GO:0005515	protein binding

0.57	GO:0016324	apical plasma membrane
0.54	GO:0009986	cell surface
0.38	GO:0070062	extracellular exosome
0.30	GO:0044422	organelle part
0.30	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane
0.30	GO:0005794	Golgi apparatus
0.30	GO:0005739	mitochondrion

sp|P43253|PI2R_RAT
Prostacyclin receptor
Search

PTGIR

0.94	Prostacyclin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0019933	cAMP-mediated signaling
0.59	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.59	GO:0032496	response to lipopolysaccharide
0.58	GO:0048662	negative regulation of smooth muscle cell proliferation
0.48	GO:0071379	cellular response to prostaglandin stimulus
0.48	GO:0034695	response to prostaglandin E
0.47	GO:1901655	cellular response to ketone
0.46	GO:0097306	cellular response to alcohol
0.45	GO:0032570	response to progesterone

0.73	GO:0004954	prostanoid receptor activity
0.35	GO:0005085	guanyl-nucleotide exchange factor activity

0.49	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P43278|H10_RAT
Histone H1.0
Search

H1F0

0.52	Glycine C-acetyltransferase

0.79	GO:0006334	nucleosome assembly
0.40	GO:0030261	chromosome condensation
0.37	GO:0006567	threonine catabolic process
0.37	GO:0032439	endosome localization
0.37	GO:0001919	regulation of receptor recycling
0.37	GO:0042632	cholesterol homeostasis
0.37	GO:0071230	cellular response to amino acid stimulus
0.37	GO:0007040	lysosome organization
0.36	GO:0032008	positive regulation of TOR signaling
0.36	GO:0043410	positive regulation of MAPK cascade

0.55	GO:0003677	DNA binding
0.48	GO:0003682	chromatin binding
0.38	GO:0008890	glycine C-acetyltransferase activity
0.35	GO:0030170	pyridoxal phosphate binding
0.35	GO:0016874	ligase activity
0.34	GO:0044877	macromolecular complex binding
0.34	GO:0003723	RNA binding
0.33	GO:0042302	structural constituent of cuticle
0.32	GO:0005515	protein binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.52	GO:0000791	euchromatin
0.47	GO:0015629	actin cytoskeleton
0.46	GO:0005794	Golgi apparatus
0.45	GO:0031974	membrane-enclosed lumen
0.37	GO:0071986	Ragulator complex
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:2.3.1.29	GO:0008890
0.38	KEGG:R00371	GO:0008890

sp|P43301|EGR3_RAT
Early growth response protein 3
Search

EGR3

0.82	Early growth response protein 3

0.57	GO:0002042	cell migration involved in sprouting angiogenesis
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0035767	endothelial cell chemotaxis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0001938	positive regulation of endothelial cell proliferation
0.55	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.54	GO:0044344	cellular response to fibroblast growth factor stimulus
0.52	GO:0043066	negative regulation of apoptotic process

0.54	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.35	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.60

GO:0005634

nucleus

sp|P43303|IL1R2_RAT
Interleukin-1 receptor type 2
Search

IL1R2

0.97	Interleukin-1 receptor type II

0.79	GO:0019221	cytokine-mediated signaling pathway
0.73	GO:0032690	negative regulation of interleukin-1 alpha production
0.72	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.71	GO:0050705	regulation of interleukin-1 alpha secretion
0.70	GO:0050711	negative regulation of interleukin-1 secretion
0.70	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.67	GO:0010955	negative regulation of protein processing
0.38	GO:0071347	cellular response to interleukin-1
0.37	GO:0006955	immune response

0.87	GO:0004910	interleukin-1, Type II, blocking receptor activity
0.69	GO:0019966	interleukin-1 binding

0.42	GO:0005737	cytoplasm
0.42	GO:0005576	extracellular region
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P43322|NRG1_RAT
Pro-neuregulin-1, membrane-bound isoform
Search

NRG1

0.96	Pro-neuregulin-1, membrane-bound

0.77	GO:0009790	embryo development
0.57	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex
0.56	GO:0045213	neurotransmitter receptor metabolic process
0.56	GO:0031643	positive regulation of myelination
0.55	GO:2001223	negative regulation of neuron migration
0.55	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade
0.55	GO:0003161	cardiac conduction system development
0.55	GO:2000010	positive regulation of protein localization to cell surface
0.55	GO:0021781	glial cell fate commitment
0.54	GO:0060999	positive regulation of dendritic spine development

0.73	GO:0005102	receptor binding
0.51	GO:0003712	transcription cofactor activity
0.49	GO:0050839	cell adhesion molecule binding
0.49	GO:0030545	receptor regulator activity
0.47	GO:0032403	protein complex binding
0.46	GO:1990782	protein tyrosine kinase binding
0.37	GO:0030296	protein tyrosine kinase activator activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.54	GO:0030673	axolemma
0.53	GO:0031594	neuromuscular junction
0.51	GO:0009897	external side of plasma membrane
0.51	GO:0030425	dendrite
0.51	GO:0044297	cell body
0.47	GO:0005576	extracellular region
0.45	GO:0005887	integral component of plasma membrane
0.45	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm
0.37	GO:0016324	apical plasma membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P43424|GALT_RAT
Galactose-1-phosphate uridylyltransferase
Search

GALT

0.58	Galactose-1-phosphate uridylyltransferase

0.82	GO:0033499	galactose catabolic process via UDP-galactose
0.51	GO:0006011	UDP-glucose metabolic process
0.42	GO:0009227	nucleotide-sugar catabolic process
0.40	GO:0019221	cytokine-mediated signaling pathway
0.39	GO:0061623	glycolytic process from galactose

0.81	GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity
0.63	GO:0008270	zinc ion binding
0.40	GO:0004896	cytokine receptor activity
0.35	GO:0005536	glucose binding
0.35	GO:0005534	galactose binding
0.34	GO:0005515	protein binding

0.48	GO:0005794	Golgi apparatus
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.81	EC:2.7.7.12	GO:0008108
0.81	KEGG:R00955	GO:0008108

sp|P43425|GBG7_RAT
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Search

GNG7

0.70	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.37	GO:0021987	cerebral cortex development
0.37	GO:0001662	behavioral fear response
0.36	GO:0032496	response to lipopolysaccharide
0.36	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0045761	regulation of adenylate cyclase activity
0.36	GO:0007626	locomotory behavior
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006915	apoptotic process

0.64	GO:0004871	signal transducer activity
0.51	GO:0030165	PDZ domain binding
0.36	GO:0042301	phosphate ion binding
0.34	GO:0051015	actin filament binding
0.34	GO:0008017	microtubule binding
0.32	GO:0016787	hydrolase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.38	GO:0070062	extracellular exosome
0.37	GO:0005884	actin filament
0.34	GO:0005874	microtubule

0.32

GO:0016787

sp|P43427|GTR5_RAT
Solute carrier family 2, facilitated glucose transporter member 5
Search

SLC2A5

0.93	Solute carrier family 2, facilitated glucose transporter member 5

0.62	GO:0008643	carbohydrate transport
0.56	GO:0071332	cellular response to fructose stimulus
0.55	GO:0055085	transmembrane transport
0.52	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal
0.47	GO:0098657	import into cell
0.35	GO:0050892	intestinal absorption
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0005975	carbohydrate metabolic process

0.62	GO:0005353	fructose transmembrane transporter activity
0.43	GO:0070061	fructose binding
0.37	GO:0005355	glucose transmembrane transporter activity

0.51	GO:0016324	apical plasma membrane
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0042383	sarcolemma
0.37	GO:0070062	extracellular exosome
0.36	GO:0035579	specific granule membrane

sp|P43428|G6PC_RAT
Glucose-6-phosphatase
Search

G6PC

0.84	Acipenser baerii glucose-6-phosphatase mRNA

0.67	GO:0016311	dephosphorylation
0.63	GO:0006094	gluconeogenesis
0.57	GO:0015712	hexose phosphate transport
0.55	GO:0042593	glucose homeostasis
0.54	GO:0046415	urate metabolic process
0.53	GO:0035264	multicellular organism growth
0.53	GO:0042632	cholesterol homeostasis
0.52	GO:0006641	triglyceride metabolic process
0.51	GO:0005980	glycogen catabolic process
0.51	GO:0051156	glucose 6-phosphate metabolic process

0.85	GO:0004346	glucose-6-phosphatase activity
0.51	GO:0042301	phosphate ion binding
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0008131	primary amine oxidase activity
0.34	GO:0048038	quinone binding
0.34	GO:0005507	copper ion binding

0.61	GO:0005783	endoplasmic reticulum
0.61	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.58	GO:0031984	organelle subcompartment
0.35	GO:0008537	proteasome activator complex
0.30	GO:0016021	integral component of membrane

0.85	EC:3.1.3.9	GO:0004346
0.85	KEGG:R00303	GO:0004346

sp|P43429|GATA1_RAT
Erythroid transcription factor
Search

GATA1

0.92	Erythroid transcription factor

0.78	GO:0030222	eosinophil differentiation
0.77	GO:0030221	basophil differentiation
0.74	GO:0030219	megakaryocyte differentiation
0.72	GO:0048821	erythrocyte development
0.66	GO:0010725	regulation of primitive erythrocyte differentiation
0.64	GO:0010724	regulation of definitive erythrocyte differentiation
0.63	GO:0045648	positive regulation of erythrocyte differentiation
0.63	GO:0071733	transcriptional activation by promoter-enhancer looping
0.62	GO:0030220	platelet formation
0.62	GO:0097067	cellular response to thyroid hormone stimulus

0.65	GO:0070742	C2H2 zinc finger domain binding
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0001085	RNA polymerase II transcription factor binding
0.61	GO:0035326	enhancer binding
0.59	GO:0008301	DNA binding, bending
0.59	GO:0002039	p53 binding
0.59	GO:0031490	chromatin DNA binding
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding

0.58	GO:0005634	nucleus
0.57	GO:0017053	transcriptional repressor complex
0.56	GO:0005667	transcription factor complex
0.52	GO:0032993	protein-DNA complex
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part

0.35

EC:3.5.1.98

GO:0032041

sp|P43527|CASP1_RAT
Caspase-1
Search

CASP1

0.87	Caspase 4, apoptosis-related cysteine peptidase

0.70	GO:0042981	regulation of apoptotic process
0.61	GO:0006508	proteolysis
0.56	GO:0012501	programmed cell death
0.55	GO:0050727	regulation of inflammatory response
0.54	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.52	GO:0050718	positive regulation of interleukin-1 beta secretion
0.51	GO:0071260	cellular response to mechanical stimulus
0.50	GO:0051882	mitochondrial depolarization
0.49	GO:0050717	positive regulation of interleukin-1 alpha secretion
0.49	GO:0071310	cellular response to organic substance

0.75	GO:0004197	cysteine-type endopeptidase activity
0.54	GO:0050700	CARD domain binding
0.46	GO:0019900	kinase binding
0.45	GO:0042802	identical protein binding
0.37	GO:0097110	scaffold protein binding
0.36	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.34	GO:0002020	protease binding

0.62	GO:0097169	AIM2 inflammasome complex
0.61	GO:0072559	NLRP3 inflammasome complex
0.61	GO:0072557	IPAF inflammasome complex
0.56	GO:0072558	NLRP1 inflammasome complex
0.51	GO:0097179	protease inhibitor complex
0.42	GO:0005783	endoplasmic reticulum
0.42	GO:0005576	extracellular region
0.41	GO:0005739	mitochondrion
0.36	GO:0043005	neuron projection
0.35	GO:0005886	plasma membrane

0.75

EC:3.4.22

GO:0004197

sp|P43884|PLIN1_RAT
Perilipin-1
Search

PLIN1

0.78

Perilipin

0.69	GO:0016042	lipid catabolic process
0.47	GO:0050995	negative regulation of lipid catabolic process
0.38	GO:0007018	microtubule-based movement

0.39	GO:0005515	protein binding
0.39	GO:0008289	lipid binding
0.38	GO:0003777	microtubule motor activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008144	drug binding

0.79	GO:0005811	lipid droplet
0.66	GO:0005829	cytosol
0.45	GO:0005783	endoplasmic reticulum
0.37	GO:0071944	cell periphery
0.30	GO:0031224	intrinsic component of membrane

sp|P45352|TYSY_RAT
Thymidylate synthase
Search

TYMS

0.46	Thymidylate synthetase

0.78	GO:0006231	dTMP biosynthetic process
0.63	GO:0032259	methylation
0.54	GO:0046683	response to organophosphorus
0.51	GO:0017148	negative regulation of translation
0.50	GO:0035999	tetrahydrofolate interconversion
0.45	GO:0060041	retina development in camera-type eye
0.43	GO:0019088	immortalization of host cell by virus
0.42	GO:0060574	intestinal epithelial cell maturation
0.42	GO:0033189	response to vitamin A
0.42	GO:0051593	response to folic acid

0.80	GO:0004799	thymidylate synthase activity
0.57	GO:1990825	sequence-specific mRNA binding
0.57	GO:0000900	translation repressor activity, nucleic acid binding
0.40	GO:0005542	folic acid binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0048037	cofactor binding
0.35	GO:1901265	nucleoside phosphate binding

0.51	GO:0005759	mitochondrial matrix
0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.45	GO:0005634	nucleus
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.80	EC:2.1.1.45	GO:0004799
0.80	KEGG:R02101	GO:0004799

sp|P45380|S26A1_RAT
Sulfate anion transporter 1
Search

SLC26A1

0.97	Sulfate anion transporter 1

0.78	GO:0019532	oxalate transport
0.74	GO:1902358	sulfate transmembrane transport
0.70	GO:1902476	chloride transmembrane transport
0.58	GO:0001503	ossification
0.50	GO:0015701	bicarbonate transport
0.49	GO:0051453	regulation of intracellular pH
0.47	GO:0042391	regulation of membrane potential
0.37	GO:0036269	swimming behavior
0.37	GO:0032474	otolith morphogenesis
0.37	GO:0048884	neuromast development

0.78	GO:0019531	oxalate transmembrane transporter activity
0.77	GO:0008271	secondary active sulfate transmembrane transporter activity
0.75	GO:0015301	anion:anion antiporter activity
0.70	GO:0015108	chloride transmembrane transporter activity
0.51	GO:0015106	bicarbonate transmembrane transporter activity
0.47	GO:0005253	anion channel activity

0.62	GO:0005887	integral component of plasma membrane
0.39	GO:0098590	plasma membrane region
0.35	GO:0005902	microvillus
0.35	GO:0045177	apical part of cell
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0070062	extracellular exosome

sp|P45446|RORB_RAT
Nuclear receptor ROR-beta
Search

RORB

0.93	Nuclear orphan receptor ROR-beta

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.63	GO:0046548	retinal rod cell development
0.62	GO:0046549	retinal cone cell development
0.61	GO:0045668	negative regulation of osteoblast differentiation
0.58	GO:0042752	regulation of circadian rhythm
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.82	GO:0004879	nuclear receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0008134	transcription factor binding
0.52	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|P45479|PPT1_RAT
Palmitoyl-protein thioesterase 1
Search

PPT1

0.83	Palmitoyl-protein thioesterase

0.84	GO:0002084	protein depalmitoylation
0.57	GO:0032429	regulation of phospholipase A2 activity
0.56	GO:0007625	grooming behavior
0.55	GO:0007040	lysosome organization
0.54	GO:0008306	associative learning
0.54	GO:0008344	adult locomotory behavior
0.53	GO:0099643	signal release from synapse
0.53	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.52	GO:0007601	visual perception
0.50	GO:0006836	neurotransmitter transport

0.83	GO:0008474	palmitoyl-(protein) hydrolase activity
0.43	GO:0016290	palmitoyl-CoA hydrolase activity
0.35	GO:0005515	protein binding

0.54	GO:0005764	lysosome
0.53	GO:0030424	axon
0.53	GO:0098793	presynapse
0.52	GO:0043025	neuronal cell body
0.52	GO:0030425	dendrite
0.49	GO:0005615	extracellular space
0.42	GO:0070382	exocytic vesicle
0.41	GO:0045121	membrane raft
0.39	GO:0005794	Golgi apparatus
0.39	GO:0005829	cytosol

0.83

EC:3.1.2.22

GO:0008474

sp|P45592|COF1_RAT
Cofilin-1
Search

CFL1

0.92	Cofilin 1, non-muscle

0.84	GO:0030042	actin filament depolymerization
0.59	GO:0030836	positive regulation of actin filament depolymerization
0.54	GO:0046716	muscle cell cellular homeostasis
0.53	GO:0009888	tissue development
0.53	GO:0045214	sarcomere organization
0.52	GO:0048513	animal organ development
0.48	GO:0044794	positive regulation by host of viral process
0.47	GO:0061001	regulation of dendritic spine morphogenesis
0.47	GO:0048864	stem cell development
0.47	GO:0043200	response to amino acid

0.74	GO:0003779	actin binding
0.55	GO:0032403	protein complex binding
0.43	GO:0005102	receptor binding
0.37	GO:0019903	protein phosphatase binding
0.37	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0046872	metal ion binding

0.74	GO:0015629	actin cytoskeleton
0.52	GO:0030018	Z disc
0.48	GO:0030027	lamellipodium
0.45	GO:0030863	cortical cytoskeleton
0.44	GO:0005911	cell-cell junction
0.44	GO:0016363	nuclear matrix
0.44	GO:0005615	extracellular space
0.42	GO:0044430	cytoskeletal part
0.41	GO:0032587	ruffle membrane
0.38	GO:1903561	extracellular vesicle

sp|P45953|ACADV_RAT
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADVL

0.95	Very long-chain specific acyl-CoA dehydrogenaseserine-threonine

0.57	GO:0046322	negative regulation of fatty acid oxidation
0.56	GO:0090181	regulation of cholesterol metabolic process
0.55	GO:0001659	temperature homeostasis
0.54	GO:0045717	negative regulation of fatty acid biosynthetic process
0.54	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.52	GO:0030855	epithelial cell differentiation
0.52	GO:0009409	response to cold
0.43	GO:0060322	head development
0.36	GO:0042760	very long-chain fatty acid catabolic process
0.36	GO:0036498	IRE1-mediated unfolded protein response

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0000062	fatty-acyl-CoA binding

0.54	GO:0042645	mitochondrial nucleoid
0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.45	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.34	GO:0036128	CatSper complex

0.74

EC:1.3.99.3

GO:0003995

sp|P46002|PTAFR_RAT
Platelet-activating factor receptor
Search

PTAFR

0.97	Platelet-activating factor receptor

0.69	GO:0006935	chemotaxis
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0032959	inositol trisphosphate biosynthetic process
0.60	GO:0031663	lipopolysaccharide-mediated signaling pathway
0.59	GO:0001816	cytokine production
0.58	GO:0048015	phosphatidylinositol-mediated signaling
0.57	GO:0006954	inflammatory response
0.50	GO:0035590	purinergic nucleotide receptor signaling pathway
0.42	GO:1904317	cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
0.42	GO:1904303	positive regulation of maternal process involved in parturition

0.86	GO:0004992	platelet activating factor receptor activity
0.61	GO:0001875	lipopolysaccharide receptor activity
0.58	GO:0001530	lipopolysaccharide binding
0.55	GO:0005543	phospholipid binding
0.51	GO:0001608	G-protein coupled nucleotide receptor activity
0.50	GO:0001614	purinergic nucleotide receptor activity
0.40	GO:0051019	mitogen-activated protein kinase binding
0.33	GO:0015057	thrombin-activated receptor activity

0.44	GO:0005887	integral component of plasma membrane
0.38	GO:0005622	intracellular
0.35	GO:0012506	vesicle membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system

sp|P46090|GPR1_RAT
G-protein coupled receptor 1
Search

GPR1

0.92	G-protein coupled receptor 1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0007268	chemical synaptic transmission
0.39	GO:0002430	complement receptor mediated signaling pathway
0.38	GO:0002283	neutrophil activation involved in immune response
0.38	GO:0050900	leukocyte migration
0.37	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0060326	cell chemotaxis
0.37	GO:0006954	inflammatory response
0.33	GO:0006939	smooth muscle contraction
0.33	GO:0042310	vasoconstriction

0.72	GO:0004930	G-protein coupled receptor activity
0.50	GO:0042923	neuropeptide binding
0.39	GO:0004875	complement receptor activity
0.38	GO:0001653	peptide receptor activity
0.34	GO:0005515	protein binding
0.33	GO:0004749	ribose phosphate diphosphokinase activity
0.33	GO:0000287	magnesium ion binding

0.50	GO:0005654	nucleoplasm
0.46	GO:0043005	neuron projection
0.44	GO:0005886	plasma membrane
0.34	GO:0060417	yolk
0.32	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:2.7.6.1	GO:0004749
0.33	KEGG:R01049	GO:0004749

sp|P46101|DPP6_RAT
Dipeptidyl aminopeptidase-like protein 6
Search

DPP6

0.92	Dipeptidyl peptidase like 6

0.58	GO:0006508	proteolysis
0.54	GO:1901379	regulation of potassium ion transmembrane transport
0.46	GO:0065009	regulation of molecular function
0.41	GO:0072659	protein localization to plasma membrane
0.38	GO:0019228	neuronal action potential
0.37	GO:0043268	positive regulation of potassium ion transport
0.37	GO:1904064	positive regulation of cation transmembrane transport
0.36	GO:1903078	positive regulation of protein localization to plasma membrane
0.35	GO:0048522	positive regulation of cellular process

0.64	GO:0017171	serine hydrolase activity
0.60	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.55	GO:0015459	potassium channel regulator activity
0.35	GO:0005515	protein binding

0.51	GO:0008076	voltage-gated potassium channel complex
0.37	GO:0070062	extracellular exosome
0.35	GO:0043025	neuronal cell body
0.35	GO:0009986	cell surface

sp|P46152|GATA4_RAT
Transcription factor GATA-4
Search

GATA4

0.92	GATA binding protein 4

0.76	GO:0003290	atrial septum secundum morphogenesis
0.75	GO:0060575	intestinal epithelial cell differentiation
0.72	GO:0045893	positive regulation of transcription, DNA-templated
0.71	GO:0003197	endocardial cushion development
0.69	GO:0008584	male gonad development
0.65	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0042493	response to drug
0.54	GO:0003260	cardioblast migration
0.54	GO:0048797	swim bladder formation
0.54	GO:0003318	cell migration to the midline involved in heart development

0.73	GO:0070410	co-SMAD binding
0.67	GO:0044212	transcription regulatory region DNA binding
0.65	GO:0003713	transcription coactivator activity
0.65	GO:0043565	sequence-specific DNA binding
0.64	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.63	GO:0008270	zinc ion binding
0.63	GO:0008134	transcription factor binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0003690	double-stranded DNA binding
0.49	GO:0003682	chromatin binding

0.64	GO:0016604	nuclear body
0.64	GO:0005667	transcription factor complex

sp|P46153|GATA6_RAT
Transcription factor GATA-6
Search

GATA6

0.88	Transcription factor GATA-6

0.70	GO:0045893	positive regulation of transcription, DNA-templated
0.65	GO:0048645	animal organ formation
0.64	GO:0001889	liver development
0.63	GO:0007493	endodermal cell fate determination
0.62	GO:0032912	negative regulation of transforming growth factor beta2 production
0.62	GO:0060486	Clara cell differentiation
0.62	GO:0048565	digestive tract development
0.62	GO:0110024	positive regulation of cardiac muscle myoblast proliferation
0.62	GO:0060510	Type II pneumocyte differentiation
0.62	GO:0051891	positive regulation of cardioblast differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0001085	RNA polymerase II transcription factor binding
0.59	GO:0070491	repressing transcription factor binding
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.57	GO:0003682	chromatin binding
0.55	GO:0003690	double-stranded DNA binding
0.54	GO:0019901	protein kinase binding
0.42	GO:0035326	enhancer binding

0.59	GO:0005634	nucleus
0.56	GO:0005667	transcription factor complex
0.48	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.45	GO:0031090	organelle membrane
0.35	GO:0070013	intracellular organelle lumen

sp|P46413|GSHB_RAT
Glutathione synthetase
Search

GSS

0.53	Glutathione synthetase

0.78	GO:0006750	glutathione biosynthetic process
0.57	GO:0046686	response to cadmium ion
0.41	GO:0043200	response to amino acid
0.41	GO:0034612	response to tumor necrosis factor
0.40	GO:0007568	aging
0.40	GO:0006520	cellular amino acid metabolic process
0.39	GO:0009410	response to xenobiotic stimulus
0.39	GO:0031667	response to nutrient levels
0.34	GO:0007399	nervous system development
0.34	GO:0006979	response to oxidative stress

0.80	GO:0004363	glutathione synthase activity
0.79	GO:0043295	glutathione binding
0.69	GO:0042803	protein homodimerization activity
0.60	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0042165	neurotransmitter binding
0.39	GO:0016597	amino acid binding

0.44	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome

0.80	EC:6.3.2.3	GO:0004363
0.80	KEGG:R00497	GO:0004363

sp|P46462|TERA_RAT
Transitional endoplasmic reticulum ATPase
Search

VCP

0.77	Transitional endoplasmic reticulum ATPase

0.59	GO:0061857	endoplasmic reticulum stress-induced pre-emptive quality control
0.58	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway
0.58	GO:1903007	positive regulation of Lys63-specific deubiquitinase activity
0.58	GO:0042728	flavin-containing compound catabolic process
0.57	GO:0070842	aggresome assembly
0.57	GO:2000158	positive regulation of ubiquitin-specific protease activity
0.56	GO:0034214	protein hexamerization
0.56	GO:0010918	positive regulation of mitochondrial membrane potential
0.56	GO:1903862	positive regulation of oxidative phosphorylation
0.56	GO:0097352	autophagosome maturation

0.57	GO:0035800	deubiquitinase activator activity
0.57	GO:1904288	BAT3 complex binding
0.56	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.56	GO:0042288	MHC class I protein binding
0.56	GO:1990381	ubiquitin-specific protease binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.53	GO:0019903	protein phosphatase binding

0.58	GO:1990730	VCP-NSFL1C complex
0.55	GO:0036513	Derlin-1 retrotranslocation complex
0.55	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.54	GO:0035861	site of double-strand break
0.53	GO:0043209	myelin sheath
0.52	GO:0005811	lipid droplet
0.51	GO:0048471	perinuclear region of cytoplasm
0.48	GO:1905369	endopeptidase complex
0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm

0.50

GO:0016787

sp|P46720|SO1A1_RAT
Solute carrier organic anion transporter family member 1A1
Search

SLCO1A2

0.62	Solute carrier organic anion transporter family member

0.58	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.46	GO:0071702	organic substance transport
0.44	GO:0010876	lipid localization
0.42	GO:0035634	response to stilbenoid
0.41	GO:0031100	animal organ regeneration
0.40	GO:0033574	response to testosterone
0.40	GO:0070327	thyroid hormone transport
0.38	GO:0050892	intestinal absorption
0.38	GO:0008206	bile acid metabolic process

0.58	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.49	GO:0015125	bile acid transmembrane transporter activity
0.41	GO:0015349	thyroid hormone transmembrane transporter activity
0.36	GO:0015350	methotrexate transmembrane transporter activity
0.35	GO:0035673	oligopeptide transmembrane transporter activity

0.55	GO:0005886	plasma membrane
0.38	GO:0005903	brush border
0.36	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

sp|P46844|BIEA_RAT
Biliverdin reductase A
Search

BLVRA

0.97	Biliverdin reductase A

0.85	GO:0042167	heme catabolic process
0.52	GO:0055114	oxidation-reduction process

0.86	GO:0004074	biliverdin reductase activity
0.62	GO:0008270	zinc ion binding
0.36	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity
0.34	GO:0005515	protein binding
0.33	GO:0000166	nucleotide binding

0.48	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.86	EC:1.3.1.24	GO:0004074
0.36	KEGG:R02082	GO:0004420

sp|P46892|CD11B_RAT
Cyclin-dependent kinase 11B
Search

CDK11B

0.67	Cyclin-dependent kinase 11B

0.63	GO:0006468	protein phosphorylation
0.44	GO:0007224	smoothened signaling pathway
0.42	GO:0007346	regulation of mitotic cell cycle
0.41	GO:0001824	blastocyst development
0.41	GO:2001234	negative regulation of apoptotic signaling pathway
0.40	GO:0051783	regulation of nuclear division
0.39	GO:0050684	regulation of mRNA processing
0.39	GO:0010564	regulation of cell cycle process
0.38	GO:0001558	regulation of cell growth
0.37	GO:0007049	cell cycle

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0060089	molecular transducer activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.39	GO:0005634	nucleus
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0012505	endomembrane system
0.35	GO:0044446	intracellular organelle part
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0031090	organelle membrane
0.34	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

sp|P46933|APBB1_RAT
Amyloid beta A4 precursor protein-binding family B member 1
Search

APBB1

0.97	Amyloid beta precursor protein binding family B member 1

0.75	GO:0043065	positive regulation of apoptotic process
0.74	GO:0000122	negative regulation of transcription by RNA polymerase II
0.70	GO:0045893	positive regulation of transcription, DNA-templated
0.62	GO:0006974	cellular response to DNA damage stimulus
0.55	GO:0050760	negative regulation of thymidylate synthase biosynthetic process
0.53	GO:0045739	positive regulation of DNA repair
0.52	GO:0043967	histone H4 acetylation
0.50	GO:0045664	regulation of neuron differentiation
0.50	GO:0010039	response to iron ion
0.49	GO:0030308	negative regulation of cell growth

0.84	GO:0070064	proline-rich region binding
0.84	GO:0001540	amyloid-beta binding
0.76	GO:0042393	histone binding
0.73	GO:0003682	chromatin binding
0.58	GO:0008134	transcription factor binding
0.52	GO:0048156	tau protein binding
0.46	GO:0032403	protein complex binding
0.42	GO:0035035	histone acetyltransferase binding

0.80	GO:0030426	growth cone
0.78	GO:0030027	lamellipodium
0.72	GO:0045202	synapse
0.60	GO:0005634	nucleus
0.55	GO:0005886	plasma membrane
0.50	GO:0044304	main axon
0.50	GO:0044309	neuron spine
0.49	GO:0030175	filopodium
0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite

sp|P46953|3HAO_RAT
3-hydroxyanthranilate 3,4-dioxygenase
Search

HAAO

0.61	3-hydroxyanthranilate 3,4-dioxygenase

0.71	GO:0043420	anthranilate metabolic process
0.71	GO:0034354	'de novo' NAD biosynthetic process from tryptophan
0.69	GO:0046874	quinolinate metabolic process
0.67	GO:0006569	tryptophan catabolic process
0.62	GO:0043650	dicarboxylic acid biosynthetic process
0.58	GO:0070050	neuron cellular homeostasis
0.57	GO:0010043	response to zinc ion
0.55	GO:0046686	response to cadmium ion
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.85	GO:0000334	3-hydroxyanthranilate 3,4-dioxygenase activity
0.70	GO:0008198	ferrous iron binding
0.35	GO:0019825	oxygen binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0009055	electron transfer activity

0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.33	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

0.85	EC:1.13.11.6	GO:0000334
0.85	KEGG:R02665	GO:0000334

sp|P47196|AKT1_RAT
RAC-alpha serine/threonine-protein kinase
Search

AKT1

0.41	RAC-alpha serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.62	GO:1990418	response to insulin-like growth factor stimulus
0.59	GO:0060416	response to growth hormone
0.56	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.55	GO:1903721	positive regulation of I-kappaB phosphorylation
0.55	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.55	GO:0010918	positive regulation of mitochondrial membrane potential
0.55	GO:0006924	activation-induced cell death of T cells
0.55	GO:0032287	peripheral nervous system myelin maintenance
0.55	GO:0031999	negative regulation of fatty acid beta-oxidation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030235	nitric-oxide synthase regulator activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0071889	14-3-3 protein binding
0.54	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.53	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.51	GO:0004712	protein serine/threonine/tyrosine kinase activity

0.52	GO:0036064	ciliary basal body
0.49	GO:0005819	spindle
0.49	GO:0005911	cell-cell junction
0.47	GO:0031982	vesicle
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.43	GO:0005739	mitochondrion
0.43	GO:0043234	protein complex
0.41	GO:0005886	plasma membrane
0.36	GO:0001726	ruffle

0.70

GO:0004674

sp|P47197|AKT2_RAT
RAC-beta serine/threonine-protein kinase
Search

AKT2

0.54	RAC-beta serine/threonine-protein kinase A

0.63	GO:0006468	protein phosphorylation
0.59	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.58	GO:0010918	positive regulation of mitochondrial membrane potential
0.58	GO:0046326	positive regulation of glucose import
0.58	GO:0032287	peripheral nervous system myelin maintenance
0.57	GO:0045725	positive regulation of glycogen biosynthetic process
0.57	GO:0043434	response to peptide hormone
0.57	GO:0031998	regulation of fatty acid beta-oxidation
0.56	GO:0097473	retinal rod cell apoptotic process
0.55	GO:1901653	cellular response to peptide

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.44	GO:0030235	nitric-oxide synthase regulator activity
0.43	GO:0071889	14-3-3 protein binding
0.43	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.43	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.43	GO:0019901	protein kinase binding

0.53	GO:0032587	ruffle membrane
0.49	GO:0005938	cell cortex
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.43	GO:0036064	ciliary basal body
0.42	GO:0005819	spindle
0.42	GO:0005911	cell-cell junction
0.41	GO:0031982	vesicle
0.38	GO:0005739	mitochondrion

0.70

GO:0004674

sp|P47198|RL22_RAT
60S ribosomal protein L22
Search

RPL22

0.59	Chromodomain helicase DNA binding protein 5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:0030217	T cell differentiation
0.44	GO:0046631	alpha-beta T cell activation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0008201	heparin binding
0.41	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.38	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0098562	cytoplasmic side of membrane

sp|P47245|NRDC_RAT
Nardilysin
Search

NRDC

0.89	Nardilysin convertase

0.60	GO:0006508	proteolysis
0.40	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.38	GO:0052548	regulation of endopeptidase activity
0.36	GO:0007528	neuromuscular junction development
0.35	GO:0008283	cell proliferation
0.35	GO:0016477	cell migration
0.33	GO:0051604	protein maturation

0.69	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0048408	epidermal growth factor binding

0.35	GO:0005739	mitochondrion
0.35	GO:0009986	cell surface
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004222

sp|P47709|RP3A_RAT
Rabphilin-3A
Search

RPH3A

0.97

Rabphilin

0.69	GO:0006886	intracellular protein transport
0.51	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.51	GO:0017158	regulation of calcium ion-dependent exocytosis
0.49	GO:0006906	vesicle fusion
0.36	GO:0010817	regulation of hormone levels
0.35	GO:0007420	brain development
0.35	GO:0031340	positive regulation of vesicle fusion
0.35	GO:1903307	positive regulation of regulated secretory pathway
0.35	GO:0050714	positive regulation of protein secretion
0.34	GO:0023056	positive regulation of signaling

0.77	GO:0017137	Rab GTPase binding
0.53	GO:0046872	metal ion binding
0.50	GO:0019905	syntaxin binding
0.49	GO:0005544	calcium-dependent phospholipid binding
0.49	GO:0030276	clathrin binding
0.40	GO:0070679	inositol 1,4,5 trisphosphate binding
0.40	GO:0008430	selenium binding
0.40	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0032403	protein complex binding
0.39	GO:0042301	phosphate ion binding

0.49	GO:0098793	presynapse
0.49	GO:0070382	exocytic vesicle
0.40	GO:0030141	secretory granule
0.40	GO:0005886	plasma membrane
0.39	GO:0030054	cell junction
0.39	GO:0030658	transport vesicle membrane
0.38	GO:0043005	neuron projection
0.38	GO:0019898	extrinsic component of membrane
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005829	cytosol

sp|P47727|CBR1_RAT
Carbonyl reductase [NADPH] 1
Search

CBR1

0.72	Non-inducible carbony reductase

0.52	GO:0055114	oxidation-reduction process
0.51	GO:0042373	vitamin K metabolic process
0.45	GO:0050890	cognition
0.44	GO:0030855	epithelial cell differentiation
0.40	GO:0017144	drug metabolic process
0.40	GO:0042376	phylloquinone catabolic process
0.37	GO:0006692	prostanoid metabolic process
0.36	GO:1901523	icosanoid catabolic process
0.36	GO:0001542	ovulation from ovarian follicle
0.36	GO:0033574	response to testosterone

0.56	GO:0004090	carbonyl reductase (NADPH) activity
0.46	GO:0047021	15-hydroxyprostaglandin dehydrogenase (NADP+) activity
0.45	GO:0050221	prostaglandin-E2 9-reductase activity
0.44	GO:0070402	NADPH binding
0.41	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.37	GO:0000253	3-keto sterol reductase activity
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.41	GO:0005829	cytosol
0.41	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0005902	microvillus
0.33	GO:0005840	ribosome
0.33	GO:0005886	plasma membrane

0.56	EC:1.1.1.184	GO:0004090
0.46	KEGG:R04552	GO:0047021

sp|P47728|CALB2_RAT
Calretinin
Search

CALB2

0.94	Testicular secretory protein Li 8

0.58	GO:0055074	calcium ion homeostasis
0.48	GO:0072027	connecting tubule development
0.48	GO:0072503	cellular divalent inorganic cation homeostasis
0.48	GO:0072221	metanephric distal convoluted tubule development
0.48	GO:0035502	metanephric part of ureteric bud development
0.47	GO:0072205	metanephric collecting duct development
0.47	GO:0007614	short-term memory
0.46	GO:1900271	regulation of long-term synaptic potentiation
0.46	GO:0007616	long-term memory
0.46	GO:0010842	retina layer formation

0.70	GO:0005509	calcium ion binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0005499	vitamin D binding

0.52	GO:0005829	cytosol
0.51	GO:0005921	gap junction
0.50	GO:0043005	neuron projection
0.49	GO:0045202	synapse
0.45	GO:0120038	plasma membrane bounded cell projection part
0.44	GO:0043025	neuronal cell body
0.43	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P47742|GBRR2_RAT
Gamma-aminobutyric acid receptor subunit rho-2
Search

GABRR2

0.97	Gamma-aminobutyric acid receptor subunit rho-2

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0007601	visual perception
0.38	GO:0006821	chloride transport
0.37	GO:0042462	eye photoreceptor cell development
0.34	GO:0007268	chemical synaptic transmission

0.78	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0005254	chloride channel activity
0.37	GO:0019904	protein domain specific binding
0.32	GO:0003676	nucleic acid binding

0.56	GO:0005886	plasma membrane
0.50	GO:1902711	GABA-A receptor complex
0.39	GO:0034707	chloride channel complex
0.38	GO:0098794	postsynapse
0.38	GO:0030054	cell junction
0.34	GO:0030424	axon

sp|P47752|S1PR2_RAT
Sphingosine 1-phosphate receptor 2
Search

S1PR2

0.94	Sphingosine 1-phosphate receptor 2

0.85	GO:0003376	sphingosine-1-phosphate signaling pathway
0.58	GO:1901552	positive regulation of endothelial cell development
0.57	GO:0090394	negative regulation of excitatory postsynaptic potential
0.57	GO:1903140	regulation of establishment of endothelial barrier
0.56	GO:0046847	filopodium assembly
0.56	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.54	GO:0031532	actin cytoskeleton reorganization
0.47	GO:0003007	heart morphogenesis
0.46	GO:0001944	vasculature development
0.45	GO:0048729	tissue morphogenesis

0.86	GO:0038036	sphingosine-1-phosphate receptor activity
0.56	GO:0001664	G-protein coupled receptor binding
0.54	GO:0005178	integrin binding
0.35	GO:0008289	lipid binding
0.35	GO:0003886	DNA (cytosine-5-)-methyltransferase activity
0.34	GO:0003682	chromatin binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003677	DNA binding
0.32	GO:0016491	oxidoreductase activity

0.43	GO:0005886	plasma membrane
0.41	GO:0009986	cell surface
0.41	GO:0098552	side of membrane
0.41	GO:0005654	nucleoplasm
0.35	GO:0098857	membrane microdomain
0.34	GO:0005768	endosome
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.1.1.37

GO:0003886

sp|P47816|PDCD2_RAT
Programmed cell death protein 2
Search

PDCD2

0.91	Programmed cell death 2 alternative transcript

0.61	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.59	GO:1901532	regulation of hematopoietic progenitor cell differentiation
0.58	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.47	GO:0060218	hematopoietic stem cell differentiation
0.46	GO:0030218	erythrocyte differentiation
0.44	GO:0007088	regulation of mitotic nuclear division
0.42	GO:0012501	programmed cell death
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.50	GO:0019899	enzyme binding
0.36	GO:0003677	DNA binding
0.36	GO:0046872	metal ion binding

0.48	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P47819|GFAP_RAT
Glial fibrillary acidic protein
Search

GFAP

0.97	Glial fibrillary acidic protein transcript variant alpha

0.59	GO:0060020	Bergmann glial cell differentiation
0.59	GO:0045109	intermediate filament organization
0.58	GO:0014002	astrocyte development
0.58	GO:0010625	positive regulation of Schwann cell proliferation
0.57	GO:1904714	regulation of chaperone-mediated autophagy
0.56	GO:0010977	negative regulation of neuron projection development
0.55	GO:0051580	regulation of neurotransmitter uptake
0.55	GO:0031102	neuron projection regeneration
0.54	GO:0060291	long-term synaptic potentiation
0.51	GO:0030198	extracellular matrix organization

0.62	GO:0005198	structural molecule activity
0.51	GO:0042802	identical protein binding
0.45	GO:1990254	keratin filament binding
0.43	GO:0097110	scaffold protein binding
0.42	GO:0008022	protein C-terminus binding
0.41	GO:0019904	protein domain specific binding
0.41	GO:0003725	double-stranded RNA binding
0.39	GO:0005178	integrin binding
0.38	GO:0019900	kinase binding
0.33	GO:0008092	cytoskeletal protein binding

0.79	GO:0005882	intermediate filament
0.57	GO:0097450	astrocyte end-foot
0.52	GO:0043209	myelin sheath
0.52	GO:0044297	cell body
0.42	GO:0005844	polysome
0.42	GO:0045335	phagocytic vesicle
0.41	GO:0031252	cell leading edge
0.41	GO:0042579	microbody
0.41	GO:0043005	neuron projection
0.40	GO:0098574	cytoplasmic side of lysosomal membrane

sp|P47820|ACE_RAT
Angiotensin-converting enzyme
Search

0.39	Angiotensin-converting enzyme

0.61	GO:0006508	proteolysis
0.30	GO:0001655	urogenital system development
0.30	GO:0040012	regulation of locomotion
0.30	GO:0050435	amyloid-beta metabolic process
0.30	GO:0070482	response to oxygen levels
0.30	GO:0071407	cellular response to organic cyclic compound
0.30	GO:1901655	cellular response to ketone
0.30	GO:0007276	gamete generation
0.30	GO:0007507	heart development
0.30	GO:0009792	embryo development ending in birth or egg hatching

0.84	GO:0008241	peptidyl-dipeptidase activity
0.72	GO:0004180	carboxypeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.54	GO:0046872	metal ion binding
0.30	GO:0019900	kinase binding
0.30	GO:0008092	cytoskeletal protein binding
0.30	GO:0008236	serine-type peptidase activity
0.30	GO:0008144	drug binding
0.30	GO:0043168	anion binding
0.30	GO:0016805	dipeptidase activity

0.30	GO:0005615	extracellular space
0.30	GO:0031410	cytoplasmic vesicle
0.30	GO:0098590	plasma membrane region
0.30	GO:0000323	lytic vacuole
0.30	GO:0031514	motile cilium
0.30	GO:0005903	brush border
0.30	GO:0044441	ciliary part
0.30	GO:0043230	extracellular organelle
0.30	GO:0016021	integral component of membrane
0.30	GO:0009897	external side of plasma membrane

0.84

EC:3.4.15

GO:0008241

sp|P47824|P2RX1_RAT
P2X purinoceptor 1
Search

0.25	Purinergic receptor P2X, ligand-gated ion channel, 1 (Fragment)

0.85	GO:0033198	response to ATP
0.84	GO:0035590	purinergic nucleotide receptor signaling pathway
0.80	GO:0060079	excitatory postsynaptic potential
0.61	GO:0098655	cation transmembrane transport

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.85	GO:0016502	nucleotide receptor activity
0.84	GO:0035586	purinergic receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0098794	postsynapse
0.67	GO:0005887	integral component of plasma membrane

sp|P47853|PGS1_RAT
Biglycan
Search

BGN

0.96

Biglycan

0.60	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.49	GO:0046426	negative regulation of JAK-STAT cascade
0.47	GO:0006469	negative regulation of protein kinase activity
0.47	GO:0019221	cytokine-mediated signaling pathway
0.42	GO:0001974	blood vessel remodeling
0.37	GO:0030207	chondroitin sulfate catabolic process
0.37	GO:0030208	dermatan sulfate biosynthetic process
0.36	GO:0030206	chondroitin sulfate biosynthetic process
0.35	GO:0030198	extracellular matrix organization

0.57	GO:0050840	extracellular matrix binding
0.53	GO:0005539	glycosaminoglycan binding
0.48	GO:0004860	protein kinase inhibitor activity
0.35	GO:0005201	extracellular matrix structural constituent
0.31	GO:0005515	protein binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.56	GO:0042383	sarcolemma
0.54	GO:0030133	transport vesicle
0.53	GO:0009986	cell surface
0.51	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen

sp|P47858|PFKAM_RAT
ATP-dependent 6-phosphofructokinase, muscle type
Search

PFKM

0.46	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.57	GO:0061718	glucose catabolic process to pyruvate
0.56	GO:0006735	NADH regeneration
0.55	GO:0050796	regulation of insulin secretion
0.55	GO:0046716	muscle cell cellular homeostasis
0.54	GO:0090277	positive regulation of peptide hormone secretion
0.53	GO:0050714	positive regulation of protein secretion
0.52	GO:0042593	glucose homeostasis
0.52	GO:0005980	glycogen catabolic process

0.79	GO:0003872	6-phosphofructokinase activity
0.60	GO:0070061	fructose binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008022	protein C-terminus binding
0.53	GO:0019900	kinase binding
0.51	GO:0042802	identical protein binding
0.50	GO:0046872	metal ion binding
0.47	GO:0046983	protein dimerization activity

0.59	GO:0005945	6-phosphofructokinase complex
0.55	GO:0097228	sperm principal piece
0.52	GO:0016324	apical plasma membrane
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.7.1.11

GO:0003872

sp|P47860|PFKAP_RAT
ATP-dependent 6-phosphofructokinase, platelet type
Search

PFKP

0.44	ATP-dependent 6-phosphofructokinase, platelet type

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.52	GO:1990830	cellular response to leukemia inhibitory factor
0.35	GO:0061718	glucose catabolic process to pyruvate
0.35	GO:0006735	NADH regeneration
0.35	GO:0051289	protein homotetramerization
0.35	GO:0030388	fructose 1,6-bisphosphate metabolic process

0.79	GO:0003872	6-phosphofructokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.50	GO:0045296	cadherin binding
0.48	GO:0032403	protein complex binding
0.36	GO:0042802	identical protein binding
0.36	GO:0070095	fructose-6-phosphate binding

0.49	GO:0005737	cytoplasm
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.34	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.30	GO:0016020	membrane

0.79

EC:2.7.1.11

GO:0003872

sp|P47861|SYT5_RAT
Synaptotagmin-5
Search

SYT5

0.81	Synaptotagmin Ib

0.73	GO:0099643	signal release from synapse
0.73	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.71	GO:0017158	regulation of calcium ion-dependent exocytosis
0.67	GO:0006836	neurotransmitter transport
0.64	GO:0001505	regulation of neurotransmitter levels
0.61	GO:0051649	establishment of localization in cell
0.57	GO:1903861	positive regulation of dendrite extension
0.54	GO:0017156	calcium ion regulated exocytosis
0.53	GO:0097479	synaptic vesicle localization
0.53	GO:0099003	vesicle-mediated transport in synapse

0.75	GO:0005544	calcium-dependent phospholipid binding
0.59	GO:0000149	SNARE binding
0.55	GO:0001786	phosphatidylserine binding
0.54	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.52	GO:0005509	calcium ion binding
0.49	GO:0030276	clathrin binding
0.49	GO:0046982	protein heterodimerization activity
0.46	GO:0050750	low-density lipoprotein particle receptor binding
0.44	GO:0048306	calcium-dependent protein binding
0.38	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding

0.73	GO:0099503	secretory vesicle
0.70	GO:0097458	neuron part
0.69	GO:0030133	transport vesicle
0.68	GO:0044456	synapse part
0.52	GO:0120025	plasma membrane bounded cell projection
0.51	GO:0044297	cell body
0.51	GO:0030659	cytoplasmic vesicle membrane
0.51	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0098805	whole membrane
0.48	GO:0098588	bounding membrane of organelle

sp|P47862|AQP3_RAT
Aquaporin-3
Search

AQP3

0.56	Aquaporin 3 (Gill blood group)

0.61	GO:0015793	glycerol transport
0.60	GO:0090650	cellular response to oxygen-glucose deprivation
0.59	GO:0070295	renal water absorption
0.57	GO:0015840	urea transport
0.56	GO:0032526	response to retinoic acid
0.55	GO:0071456	cellular response to hypoxia
0.55	GO:0055085	transmembrane transport
0.54	GO:0042476	odontogenesis
0.51	GO:0002684	positive regulation of immune system process
0.41	GO:0015700	arsenite transport

0.69	GO:0022803	passive transmembrane transporter activity
0.61	GO:0015168	glycerol transmembrane transporter activity
0.44	GO:0005372	water transmembrane transporter activity
0.42	GO:0015204	urea transmembrane transporter activity
0.41	GO:0015105	arsenite transmembrane transporter activity

0.54	GO:0016323	basolateral plasma membrane
0.52	GO:0005911	cell-cell junction
0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.34	GO:0046930	pore complex
0.33	GO:0005887	integral component of plasma membrane

sp|P47863|AQP4_RAT
Aquaporin-4
Search

AQP4

0.95	Aquaporin 4 transcript variant a

0.58	GO:0050891	multicellular organismal water homeostasis
0.57	GO:0071346	cellular response to interferon-gamma
0.55	GO:0055085	transmembrane transport
0.48	GO:0006833	water transport
0.39	GO:0006811	ion transport
0.38	GO:0003014	renal system process
0.36	GO:0007605	sensory perception of sound
0.36	GO:0060354	negative regulation of cell adhesion molecule production
0.36	GO:0015670	carbon dioxide transport
0.35	GO:0032691	negative regulation of interleukin-1 beta production

0.69	GO:0022803	passive transmembrane transporter activity
0.48	GO:0005372	water transmembrane transporter activity
0.37	GO:0042802	identical protein binding
0.34	GO:0008146	sulfotransferase activity

0.55	GO:0009897	external side of plasma membrane
0.46	GO:0016323	basolateral plasma membrane
0.41	GO:0005887	integral component of plasma membrane
0.39	GO:0005737	cytoplasm
0.36	GO:0005911	cell-cell junction
0.36	GO:0046930	pore complex
0.35	GO:0030315	T-tubule
0.35	GO:0045178	basal part of cell
0.35	GO:0031253	cell projection membrane
0.33	GO:0098588	bounding membrane of organelle

0.34

GO:0008146

sp|P47864|AQP5_RAT
Aquaporin-5
Search

AQP5

0.54	LOW QUALITY PROTEIN: aquaporin-5

0.57	GO:0006833	water transport
0.56	GO:0030157	pancreatic juice secretion
0.55	GO:0015670	carbon dioxide transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0046541	saliva secretion
0.52	GO:0042476	odontogenesis
0.51	GO:0048593	camera-type eye morphogenesis
0.47	GO:0071288	cellular response to mercury ion
0.46	GO:0071280	cellular response to copper ion
0.46	GO:0015793	glycerol transport

0.69	GO:0022803	passive transmembrane transporter activity
0.57	GO:0005372	water transmembrane transporter activity
0.48	GO:0042802	identical protein binding
0.46	GO:0015168	glycerol transmembrane transporter activity
0.34	GO:0030165	PDZ domain binding
0.34	GO:0005179	hormone activity
0.33	GO:0003779	actin binding

0.56	GO:0016324	apical plasma membrane
0.53	GO:0009925	basal plasma membrane
0.52	GO:0005902	microvillus
0.48	GO:0012505	endomembrane system
0.44	GO:0070062	extracellular exosome
0.42	GO:0044444	cytoplasmic part
0.41	GO:0005887	integral component of plasma membrane
0.41	GO:0097708	intracellular vesicle
0.41	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0012506	vesicle membrane

sp|P47866|CRFR2_RAT
Corticotropin-releasing factor receptor 2
Search

CRHR2

0.92	Corticotropin releasing factor receptor type 2 beta

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0043435	response to corticotropin-releasing hormone
0.40	GO:0032099	negative regulation of appetite
0.38	GO:0009755	hormone-mediated signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.42	GO:0043404	corticotropin-releasing hormone receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P47868|SCG3_RAT
Secretogranin-3
Search

SCG3

0.97	Secretogranin III

0.55	GO:0002576	platelet degranulation
0.51	GO:0043687	post-translational protein modification

0.47	GO:0003723	RNA binding
0.44	GO:0005515	protein binding
0.36	GO:0003677	DNA binding

0.75	GO:0030658	transport vesicle membrane
0.64	GO:0005576	extracellular region
0.54	GO:0034774	secretory granule lumen
0.52	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P47875|CSRP1_RAT
Cysteine and glycine-rich protein 1
Search

CSRP1

0.92	Cysteine and glycine-rich protein 1

0.40	GO:0031102	neuron projection regeneration
0.40	GO:0060027	convergent extension involved in gastrulation
0.40	GO:0042074	cell migration involved in gastrulation
0.40	GO:0007254	JNK cascade
0.39	GO:0003007	heart morphogenesis
0.38	GO:0016055	Wnt signaling pathway
0.37	GO:0070527	platelet aggregation
0.34	GO:0006937	regulation of muscle contraction
0.34	GO:0030036	actin cytoskeleton organization

0.54	GO:0046872	metal ion binding
0.35	GO:0051393	alpha-actinin binding
0.34	GO:0051219	phosphoprotein binding
0.34	GO:0003723	RNA binding

0.52	GO:0097517	contractile actin filament bundle
0.52	GO:0042641	actomyosin
0.51	GO:0005925	focal adhesion
0.50	GO:0031252	cell leading edge
0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0099512	supramolecular fiber
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex

sp|P47940|RES18_RAT
Regulated endocrine-specific protein 18
Search

RESP18

0.97	Regulated endocrine-specific protein 18

0.78	GO:0001701	in utero embryonic development
0.37	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0006508	proteolysis

0.37	GO:0004725	protein tyrosine phosphatase activity
0.36	GO:0004177	aminopeptidase activity
0.35	GO:0008270	zinc ion binding

0.70	GO:0005783	endoplasmic reticulum
0.55	GO:0005794	Golgi apparatus
0.52	GO:0005576	extracellular region
0.50	GO:0043204	perikaryon
0.48	GO:0030141	secretory granule
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.37

GO:0004725

sp|P47942|DPYL2_RAT
Dihydropyrimidinase-related protein 2
Search

DPYSL2

0.95	Dihydropyrimidinase-related protein 2 isoform B

0.84	GO:0030516	regulation of axon extension
0.81	GO:0007411	axon guidance
0.79	GO:0007420	brain development
0.71	GO:0007010	cytoskeleton organization
0.42	GO:0014049	positive regulation of glutamate secretion
0.41	GO:0001975	response to amphetamine
0.41	GO:0042220	response to cocaine
0.40	GO:0021510	spinal cord development
0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0097480	establishment of synaptic vesicle localization

0.74	GO:0008017	microtubule binding
0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.44	GO:0019901	protein kinase binding
0.38	GO:0042802	identical protein binding

0.48	GO:0005737	cytoplasm
0.46	GO:0043209	myelin sheath
0.45	GO:0043025	neuronal cell body
0.45	GO:0030425	dendrite
0.45	GO:0030424	axon
0.40	GO:0005874	microtubule
0.40	GO:0043679	axon terminus
0.40	GO:0030426	growth cone
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0005886	plasma membrane

0.65

EC:3.5

GO:0016810

sp|P47967|LEG5_RAT
Galectin-5
Search

0.39

Galectin

0.46	GO:0008039	synaptic target recognition
0.36	GO:1904977	lymphatic endothelial cell migration
0.35	GO:0098792	xenophagy
0.35	GO:0002376	immune system process
0.35	GO:0098586	cellular response to virus
0.34	GO:0006468	protein phosphorylation
0.34	GO:0035556	intracellular signal transduction

0.70	GO:0030246	carbohydrate binding
0.48	GO:0016936	galactoside binding
0.35	GO:0005178	integrin binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.41	GO:0005829	cytosol
0.35	GO:0005576	extracellular region
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P47971|NPTX1_RAT
Neuronal pentraxin-1
Search

NPTX1

0.97	Neuronal pentraxin I

0.81	GO:0060385	axonogenesis involved in innervation
0.53	GO:0008306	associative learning
0.41	GO:0035865	cellular response to potassium ion
0.40	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.40	GO:0007268	chemical synaptic transmission
0.39	GO:0071333	cellular response to glucose stimulus
0.39	GO:0050804	modulation of chemical synaptic transmission
0.38	GO:0007417	central nervous system development
0.38	GO:0006839	mitochondrial transport
0.37	GO:0042752	regulation of circadian rhythm

0.41	GO:0046872	metal ion binding
0.35	GO:0030246	carbohydrate binding

0.43	GO:0030133	transport vesicle
0.43	GO:0005576	extracellular region
0.38	GO:0043005	neuron projection
0.35	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P47973|TTP_RAT
mRNA decay activator protein ZFP36
Search

ZFP36

0.96	Tristetraproline

0.68	GO:1904246	negative regulation of polynucleotide adenylyltransferase activity
0.66	GO:0045085	negative regulation of interleukin-2 biosynthetic process
0.65	GO:0061158	3'-UTR-mediated mRNA destabilization
0.65	GO:0038066	p38MAPK cascade
0.64	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.62	GO:0045600	positive regulation of fat cell differentiation
0.62	GO:0035278	miRNA mediated inhibition of translation
0.62	GO:0045638	negative regulation of myeloid cell differentiation
0.61	GO:0071356	cellular response to tumor necrosis factor
0.60	GO:0071222	cellular response to lipopolysaccharide

0.64	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.64	GO:0071889	14-3-3 protein binding
0.57	GO:0070063	RNA polymerase binding
0.54	GO:0046872	metal ion binding
0.42	GO:0019957	C-C chemokine binding
0.42	GO:0031072	heat shock protein binding
0.40	GO:0019901	protein kinase binding
0.37	GO:0003677	DNA binding
0.36	GO:0003727	single-stranded RNA binding
0.33	GO:0070577	lysine-acetylated histone binding

0.60	GO:0030014	CCR4-NOT complex
0.52	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.48	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0098745	Dcp1-Dcp2 complex
0.45	GO:0070578	RISC-loading complex
0.43	GO:0000178	exosome (RNase complex)
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P47987|PLLP_RAT
Plasmolipin
Search

PLLP

0.97	Plasmolipin

0.53	GO:0001766	membrane raft polarization
0.51	GO:0042552	myelination
0.43	GO:0008104	protein localization
0.40	GO:0048546	digestive tract morphogenesis
0.40	GO:0030100	regulation of endocytosis
0.39	GO:0009611	response to wounding
0.36	GO:0006811	ion transport
0.35	GO:0010469	regulation of receptor activity
0.34	GO:0006935	chemotaxis
0.33	GO:0006072	glycerol-3-phosphate metabolic process

0.52	GO:0019911	structural constituent of myelin sheath
0.35	GO:0005125	cytokine activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity

0.50	GO:0045121	membrane raft
0.42	GO:0005654	nucleoplasm
0.41	GO:0043218	compact myelin
0.37	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.33	GO:0005840	ribosome
0.33	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.30	GO:0016021	integral component of membrane

0.33	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.33	KEGG:R00842	GO:0004367

sp|P48004|PSA7_RAT
Proteasome subunit alpha type-7
Search

PSMA7

0.49	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.67	GO:0043632	modification-dependent macromolecule catabolic process
0.37	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.37	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.37	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.37	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:1902036	regulation of hematopoietic stem cell differentiation
0.37	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.36	GO:0070498	interleukin-1-mediated signaling pathway
0.36	GO:0038061	NIK/NF-kappaB signaling

0.77	GO:0004298	threonine-type endopeptidase activity
0.49	GO:0042802	identical protein binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.57	GO:0005634	nucleus
0.50	GO:0098794	postsynapse
0.49	GO:0005737	cytoplasm
0.48	GO:1990111	spermatoproteasome complex
0.38	GO:0070062	extracellular exosome
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005667	transcription factor complex

0.77

GO:0004298

sp|P48032|TIMP3_RAT
Metalloproteinase inhibitor 3
Search

TIMP3

0.93	TIMP metallopeptidase inhibitor 3

0.76	GO:0010951	negative regulation of endopeptidase activity
0.74	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.73	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.68	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.61	GO:1904683	regulation of metalloendopeptidase activity
0.61	GO:1905049	negative regulation of metallopeptidase activity
0.55	GO:0010033	response to organic substance
0.49	GO:0070887	cellular response to chemical stimulus

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.51	GO:0002020	protease binding

0.66

GO:0005576

extracellular region

sp|P48037|ANXA6_RAT
Annexin A6
Search

ANXA6

0.52

Annexin

0.63	GO:0051560	mitochondrial calcium ion homeostasis
0.60	GO:0006937	regulation of muscle contraction
0.59	GO:0097190	apoptotic signaling pathway
0.57	GO:0006816	calcium ion transport
0.56	GO:0051260	protein homooligomerization
0.47	GO:0034220	ion transmembrane transport
0.41	GO:0051283	negative regulation of sequestering of calcium ion
0.39	GO:0003418	growth plate cartilage chondrocyte differentiation
0.38	GO:0031214	biomineral tissue development
0.37	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.61	GO:0048306	calcium-dependent protein binding
0.60	GO:0015485	cholesterol binding
0.56	GO:0015276	ligand-gated ion channel activity
0.55	GO:0042803	protein homodimerization activity
0.50	GO:0032550	purine ribonucleoside binding
0.50	GO:0019001	guanyl nucleotide binding
0.43	GO:0032555	purine ribonucleotide binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0031902	late endosome membrane
0.59	GO:0005765	lysosomal membrane
0.58	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005739	mitochondrion
0.44	GO:0042470	melanosome
0.42	GO:0005925	focal adhesion
0.40	GO:0070062	extracellular exosome
0.39	GO:0042584	chromaffin granule membrane
0.38	GO:0014704	intercalated disc
0.38	GO:0042383	sarcolemma

sp|P48056|S6A12_RAT
Sodium- and chloride-dependent betaine transporter
Search

SLC6A12

0.49	Sodium- and chloride-dependent betaine transporter

0.74	GO:0015812	gamma-aminobutyric acid transport
0.54	GO:0055085	transmembrane transport
0.36	GO:0009992	cellular water homeostasis
0.35	GO:0071474	cellular hyperosmotic response
0.34	GO:0010033	response to organic substance
0.34	GO:0032259	methylation

0.78	GO:0005332	gamma-aminobutyric acid:sodium symporter activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.60	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

0.34

GO:0008168

sp|P48199|CRP_RAT
C-reactive protein
Search

CRP

0.83

Pentaxin

0.54	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.54	GO:2000482	regulation of interleukin-8 secretion
0.54	GO:0032930	positive regulation of superoxide anion generation
0.54	GO:0010888	negative regulation of lipid storage
0.52	GO:0097756	negative regulation of blood vessel diameter
0.47	GO:0010628	positive regulation of gene expression
0.46	GO:0052403	negative regulation by host of symbiont catalytic activity
0.46	GO:0044867	modulation by host of viral catalytic activity
0.46	GO:1903016	negative regulation of exo-alpha-sialidase activity
0.46	GO:0044870	modulation by host of viral glycoprotein metabolic process

0.59	GO:0001849	complement component C1q binding
0.54	GO:0030169	low-density lipoprotein particle binding
0.53	GO:0046872	metal ion binding
0.53	GO:0050750	low-density lipoprotein particle receptor binding
0.50	GO:0042802	identical protein binding
0.47	GO:0046790	virion binding
0.35	GO:0015485	cholesterol binding
0.35	GO:0030246	carbohydrate binding
0.34	GO:0033265	choline binding
0.34	GO:0046983	protein dimerization activity

0.65	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.35	GO:0030175	filopodium
0.35	GO:0030426	growth cone
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P48284|CAH4_RAT
Carbonic anhydrase 4
Search

CA4

0.97	Carbonic anhydrase IV b

0.64	GO:0006730	one-carbon metabolic process
0.55	GO:0015701	bicarbonate transport
0.37	GO:0015670	carbon dioxide transport
0.36	GO:0006885	regulation of pH
0.36	GO:0048545	response to steroid hormone
0.35	GO:0048513	animal organ development
0.34	GO:0035813	regulation of renal sodium excretion
0.34	GO:0035810	positive regulation of urine volume

0.75	GO:0004089	carbonate dehydratase activity
0.61	GO:0008270	zinc ion binding
0.36	GO:0005515	protein binding

0.71	GO:0031225	anchored component of membrane
0.55	GO:0031233	intrinsic component of external side of plasma membrane
0.55	GO:0031526	brush border membrane
0.54	GO:0030667	secretory granule membrane
0.53	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.53	GO:0016324	apical plasma membrane
0.53	GO:0005791	rough endoplasmic reticulum
0.52	GO:0070062	extracellular exosome
0.52	GO:0005802	trans-Golgi network
0.51	GO:0048471	perinuclear region of cytoplasm

0.75

EC:4.2.1.1

GO:0004089

sp|P48303|S1PR1_RAT
Sphingosine 1-phosphate receptor 1
Search

S1PR1

0.93	Endothelial differentiation, sphingolipid G-protein-coupled receptor, 1

0.85	GO:0003376	sphingosine-1-phosphate signaling pathway
0.56	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis
0.54	GO:0001955	blood vessel maturation
0.54	GO:0072678	T cell migration
0.53	GO:0045124	regulation of bone resorption
0.53	GO:0061384	heart trabecula morphogenesis
0.53	GO:0030032	lamellipodium assembly
0.52	GO:0030500	regulation of bone mineralization
0.52	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.51	GO:0030595	leukocyte chemotaxis

0.86	GO:0038036	sphingosine-1-phosphate receptor activity
0.50	GO:0001664	G-protein coupled receptor binding
0.38	GO:0046625	sphingolipid binding

0.50	GO:0009897	external side of plasma membrane
0.46	GO:0005654	nucleoplasm
0.45	GO:0031226	intrinsic component of plasma membrane
0.38	GO:0045121	membrane raft
0.37	GO:0005768	endosome
0.34	GO:0098590	plasma membrane region
0.30	GO:0016021	integral component of membrane

sp|P48317|GA45A_RAT
Growth arrest and DNA damage-inducible protein GADD45 alpha
Search

GADD45A

0.97	Growth arrest and DNA-damage-inducible protein alpha

0.72	GO:0051726	regulation of cell cycle
0.63	GO:0000185	activation of MAPKKK activity
0.63	GO:1900745	positive regulation of p38MAPK cascade
0.61	GO:0006950	response to stress
0.60	GO:0046330	positive regulation of JNK cascade
0.57	GO:0006469	negative regulation of protein kinase activity
0.57	GO:0043065	positive regulation of apoptotic process
0.56	GO:0071260	cellular response to mechanical stimulus
0.55	GO:0071479	cellular response to ionizing radiation
0.55	GO:2000379	positive regulation of reactive oxygen species metabolic process

0.56	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.55	GO:0047485	protein N-terminus binding
0.52	GO:0019900	kinase binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.33	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.47	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

sp|P48442|CASR_RAT
Extracellular calcium-sensing receptor
Search

CASR

0.90	Extracellular calcium-sensing receptor

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0005513	detection of calcium ion
0.61	GO:0055074	calcium ion homeostasis
0.60	GO:0070509	calcium ion import
0.58	GO:0072503	cellular divalent inorganic cation homeostasis
0.58	GO:0051924	regulation of calcium ion transport
0.57	GO:0032781	positive regulation of ATPase activity
0.55	GO:0006875	cellular metal ion homeostasis
0.53	GO:0010628	positive regulation of gene expression
0.45	GO:0042311	vasodilation

0.70	GO:0004930	G-protein coupled receptor activity
0.56	GO:0016597	amino acid binding
0.55	GO:0042803	protein homodimerization activity
0.53	GO:0005509	calcium ion binding
0.43	GO:0044325	ion channel binding
0.42	GO:0005178	integrin binding
0.41	GO:0019808	polyamine binding
0.41	GO:0019901	protein kinase binding
0.38	GO:0000287	magnesium ion binding
0.36	GO:0004435	phosphatidylinositol phospholipase C activity

0.53	GO:0005886	plasma membrane
0.44	GO:0043679	axon terminus
0.42	GO:0043025	neuronal cell body
0.41	GO:0045177	apical part of cell
0.41	GO:0030424	axon
0.40	GO:0009986	cell surface
0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.36	EC:3.1.4.11	GO:0004435
0.36	KEGG:R03435	GO:0004435

sp|P48450|ERG7_RAT
Lanosterol synthase
Search

LSS

0.69	Terpene cyclase/mutase family member

0.54	GO:0006695	cholesterol biosynthetic process
0.51	GO:0031647	regulation of protein stability

0.66

GO:0016866

intramolecular transferase activity

0.53	GO:0005811	lipid droplet
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:5.4

GO:0016866

sp|P48500|TPIS_RAT
Triosephosphate isomerase
Search

TPI1

0.47	Triosephosphate isomerase B

0.73	GO:0019319	hexose biosynthetic process
0.72	GO:0006098	pentose-phosphate shunt
0.71	GO:0006006	glucose metabolic process
0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.49	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.45	GO:0007275	multicellular organism development
0.44	GO:0046174	polyol catabolic process
0.44	GO:0006071	glycerol metabolic process

0.78	GO:0004807	triose-phosphate isomerase activity
0.48	GO:0031625	ubiquitin protein ligase binding

0.42	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.78	EC:5.3.1.1	GO:0004807
0.78	KEGG:R01015	GO:0004807

sp|P48508|GSH0_RAT
Glutamate--cysteine ligase regulatory subunit
Search

GCLM

0.89	Gamma-glutamylcysteine synthetase regulatory subunit

0.78	GO:0006750	glutathione biosynthetic process
0.63	GO:0035227	regulation of glutamate-cysteine ligase activity
0.62	GO:0051351	positive regulation of ligase activity
0.59	GO:0051900	regulation of mitochondrial depolarization
0.57	GO:0008637	apoptotic mitochondrial changes
0.57	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.57	GO:1990830	cellular response to leukemia inhibitory factor
0.55	GO:0050880	regulation of blood vessel size
0.51	GO:0006534	cysteine metabolic process
0.51	GO:0006536	glutamate metabolic process

0.85	GO:0035226	glutamate-cysteine ligase catalytic subunit binding
0.56	GO:0016874	ligase activity
0.51	GO:0046982	protein heterodimerization activity
0.44	GO:0030234	enzyme regulator activity
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0016740	transferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0017109	glutamate-cysteine ligase complex
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.56

GO:0016874

sp|P48548|KCNJ5_RAT
G protein-activated inward rectifier potassium channel 4
Search

KCNJ5

0.97	G protein-activated inward rectifier potassium channel 4

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.59	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.56	GO:0086091	regulation of heart rate by cardiac conduction
0.55	GO:0099587	inorganic ion import across plasma membrane
0.35	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential
0.35	GO:0071315	cellular response to morphine
0.34	GO:0051602	response to electrical stimulus

0.84	GO:0015467	G-protein activated inward rectifier potassium channel activity
0.59	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
0.35	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
0.35	GO:0005515	protein binding

0.52	GO:0008076	voltage-gated potassium channel complex
0.38	GO:0030315	T-tubule
0.37	GO:0009897	external side of plasma membrane
0.34	GO:0032809	neuronal cell body membrane
0.34	GO:0005794	Golgi apparatus
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

sp|P48550|KCNJ6_RAT
G protein-activated inward rectifier potassium channel 2
Search

KCNJ6

0.97	G protein-activated inward rectifier potassium channel 2

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.42	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.41	GO:0086091	regulation of heart rate by cardiac conduction
0.40	GO:0098739	import across plasma membrane
0.36	GO:0071315	cellular response to morphine
0.35	GO:0051602	response to electrical stimulus
0.35	GO:0099625	ventricular cardiac muscle cell membrane repolarization

0.86	GO:0015467	G-protein activated inward rectifier potassium channel activity
0.42	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
0.35	GO:0001965	G-protein alpha-subunit binding
0.35	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

0.44	GO:0005887	integral component of plasma membrane
0.40	GO:0034705	potassium channel complex
0.35	GO:0032809	neuronal cell body membrane
0.35	GO:0009986	cell surface
0.35	GO:0005794	Golgi apparatus
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.34	GO:0030315	T-tubule
0.33	GO:0098552	side of membrane

sp|P48675|DESM_RAT
Desmin
Search

DES

0.97	Muscle-specific intermediate filament desmin (Predicted)

0.58	GO:0045109	intermediate filament organization
0.47	GO:0006936	muscle contraction
0.47	GO:0007517	muscle organ development
0.46	GO:0007626	locomotory behavior
0.44	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.43	GO:0045214	sarcomere organization
0.43	GO:0060047	heart contraction
0.42	GO:0014706	striated muscle tissue development
0.36	GO:0045107	intermediate filament polymerization
0.36	GO:0033275	actin-myosin filament sliding

0.62	GO:0005198	structural molecule activity
0.50	GO:0042802	identical protein binding
0.49	GO:0008092	cytoskeletal protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0005882	intermediate filament
0.59	GO:0030018	Z disc
0.58	GO:0005916	fascia adherens
0.58	GO:0097512	cardiac myofibril
0.57	GO:0042383	sarcolemma
0.56	GO:0031594	neuromuscular junction
0.45	GO:0005634	nucleus
0.44	GO:0097433	dense body
0.36	GO:0070062	extracellular exosome
0.35	GO:0005921	gap junction

0.33

GO:0004674

sp|P48679|LMNA_RAT
Prelamin-A/C
Search

LMNA

0.95	Lamin A/C transcript variant 1

0.61	GO:0035105	sterol regulatory element binding protein import into nucleus
0.61	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress
0.60	GO:0090343	positive regulation of cell aging
0.59	GO:0072201	negative regulation of mesenchymal cell proliferation
0.59	GO:0055015	ventricular cardiac muscle cell development
0.58	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.58	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.56	GO:0071456	cellular response to hypoxia
0.56	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.56	GO:0006998	nuclear envelope organization

0.62	GO:0005198	structural molecule activity
0.37	GO:0042802	identical protein binding
0.36	GO:0008157	protein phosphatase 1 binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005882	intermediate filament
0.59	GO:0005652	nuclear lamina
0.54	GO:0031965	nuclear membrane
0.50	GO:0005654	nucleoplasm
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0031012	extracellular matrix
0.36	GO:0016363	nuclear matrix
0.34	GO:0005829	cytosol
0.34	GO:0019031	viral envelope

sp|P48721|GRP75_RAT
Stress-70 protein, mitochondrial
Search

HSPA9

0.84	LOW QUALITY PROTEIN: stress-70 protein, mitochondrial

0.68	GO:0006457	protein folding
0.63	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.62	GO:0045647	negative regulation of erythrocyte differentiation
0.59	GO:0030218	erythrocyte differentiation
0.56	GO:0006611	protein export from nucleus
0.53	GO:0016226	iron-sulfur cluster assembly
0.41	GO:0071345	cellular response to cytokine stimulus
0.41	GO:0060548	negative regulation of cell death
0.40	GO:0097068	response to thyroxine
0.40	GO:0051593	response to folic acid

0.70	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0017134	fibroblast growth factor binding
0.38	GO:0031072	heat shock protein binding
0.38	GO:0051087	chaperone binding
0.37	GO:0003723	RNA binding

0.54	GO:0042645	mitochondrial nucleoid
0.54	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.42	GO:0031012	extracellular matrix
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome

sp|P48750|CSF2_RAT
Granulocyte-macrophage colony-stimulating factor
Search

CSF2

0.97	Granulocyte-macrophage colony-stimulating factor

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.69	GO:0045918	negative regulation of cytolysis
0.69	GO:0032747	positive regulation of interleukin-23 production
0.68	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.68	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.68	GO:0071803	positive regulation of podosome assembly
0.67	GO:0043011	myeloid dendritic cell differentiation
0.66	GO:1901099	negative regulation of signal transduction in absence of ligand
0.66	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.87	GO:0005129	granulocyte macrophage colony-stimulating factor receptor binding
0.78	GO:0008083	growth factor activity
0.64	GO:0005125	cytokine activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.46	GO:0043227	membrane-bounded organelle
0.44	GO:0043229	intracellular organelle

0.36

GO:0004713

sp|P48763|SL9A2_RAT
Sodium/hydrogen exchanger 2
Search

SLC9A2

0.59	Sodium/hydrogen exchanger

0.79	GO:0006885	regulation of pH
0.77	GO:0035725	sodium ion transmembrane transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.52	GO:0099587	inorganic ion import across plasma membrane
0.50	GO:0030004	cellular monovalent inorganic cation homeostasis
0.50	GO:0001696	gastric acid secretion
0.47	GO:0002064	epithelial cell development
0.47	GO:0008104	protein localization
0.47	GO:0071805	potassium ion transmembrane transport
0.34	GO:0042539	hypotonic salinity response

0.82	GO:0015385	sodium:proton antiporter activity
0.52	GO:0015386	potassium:proton antiporter activity

0.40	GO:0005886	plasma membrane
0.38	GO:0045177	apical part of cell
0.37	GO:0005903	brush border
0.30	GO:0016021	integral component of membrane

sp|P48768|NAC2_RAT
Sodium/calcium exchanger 2
Search

0.81	Solute carrier family 8 (sodium/calcium exchanger), member 3

0.77	GO:0035725	sodium ion transmembrane transport
0.77	GO:0006816	calcium ion transport
0.60	GO:0007154	cell communication
0.59	GO:0060291	long-term synaptic potentiation
0.57	GO:0007613	memory
0.57	GO:0007612	learning
0.56	GO:0006874	cellular calcium ion homeostasis
0.52	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.51	GO:0014819	regulation of skeletal muscle contraction
0.49	GO:0048709	oligodendrocyte differentiation

0.85	GO:0005432	calcium:sodium antiporter activity
0.53	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential

0.49	GO:0031594	neuromuscular junction
0.49	GO:0031226	intrinsic component of plasma membrane
0.49	GO:0042383	sarcolemma
0.48	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005741	mitochondrial outer membrane
0.44	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|P48769|DCK_RAT
Deoxycytidine kinase
Search

DCK

0.61	Deoxynucleoside kinase

0.63	GO:0009165	nucleotide biosynthetic process
0.52	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
0.51	GO:0016310	phosphorylation
0.48	GO:0006220	pyrimidine nucleotide metabolic process
0.36	GO:0046092	deoxycytidine metabolic process
0.34	GO:0046053	dAMP metabolic process
0.34	GO:0043097	pyrimidine nucleoside salvage
0.34	GO:0072522	purine-containing compound biosynthetic process
0.33	GO:0046385	deoxyribose phosphate biosynthetic process
0.33	GO:0009127	purine nucleoside monophosphate biosynthetic process

0.77	GO:0019206	nucleoside kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042803	protein homodimerization activity
0.36	GO:0032548	pyrimidine deoxyribonucleoside binding
0.33	GO:0000287	magnesium ion binding
0.32	GO:0046982	protein heterodimerization activity
0.31	GO:0003677	DNA binding

0.45	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.32	GO:0000786	nucleosome

sp|P48807|FGF5_RAT
Fibroblast growth factor 5
Search

FGF5

0.62	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.74	GO:0010469	regulation of receptor activity
0.62	GO:0023019	signal transduction involved in regulation of gene expression
0.59	GO:0010001	glial cell differentiation
0.57	GO:0008284	positive regulation of cell proliferation
0.46	GO:0061550	cranial ganglion development
0.42	GO:0051781	positive regulation of cell division
0.37	GO:0008283	cell proliferation
0.36	GO:0001502	cartilage condensation
0.36	GO:0045445	myoblast differentiation

0.84	GO:0005104	fibroblast growth factor receptor binding
0.77	GO:0008083	growth factor activity
0.37	GO:0005163	nerve growth factor receptor binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.65	GO:0005576	extracellular region
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P48961|CCND3_RAT
G1/S-specific cyclin-D3
Search

CCND3

0.87	Cyclin D3 (Predicted)

0.67	GO:0007049	cell cycle
0.58	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.58	GO:0042098	T cell proliferation
0.57	GO:0046626	regulation of insulin receptor signaling pathway
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.54	GO:0042127	regulation of cell proliferation
0.46	GO:0007165	signal transduction
0.44	GO:0070141	response to UV-A
0.44	GO:0044783	G1 DNA damage checkpoint
0.44	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle

0.57	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.56	GO:0019901	protein kinase binding
0.42	GO:0003714	transcription corepressor activity
0.42	GO:0070064	proline-rich region binding
0.41	GO:0042826	histone deacetylase binding
0.40	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.39	GO:0008134	transcription factor binding
0.36	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.58	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.42	GO:0017053	transcriptional repressor complex
0.40	GO:0005923	bicellular tight junction
0.40	GO:0005737	cytoplasm
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.57

EC:2.7.11.22

GO:0004693

sp|P48965|MPIP1_RAT
M-phase inducer phosphatase 1
Search

CDC25A

0.96	Cell division cycle 25 homolog A

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.64	GO:0034644	cellular response to UV
0.48	GO:0051301	cell division
0.47	GO:0045931	positive regulation of mitotic cell cycle
0.45	GO:0009794	regulation of mitotic cell cycle, embryonic
0.43	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.42	GO:0007144	female meiosis I
0.42	GO:0032467	positive regulation of cytokinesis
0.42	GO:0001556	oocyte maturation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.62	GO:0019901	protein kinase binding
0.59	GO:0051087	chaperone binding

0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.41	GO:0000922	spindle pole
0.40	GO:0005813	centrosome

0.75

GO:0004725

sp|P48966|MPIP2_RAT
M-phase inducer phosphatase 2
Search

CDC25B

0.89	Cell division cycle 25 homolog B

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.66	GO:0007144	female meiosis I
0.65	GO:0001556	oocyte maturation
0.64	GO:0045931	positive regulation of mitotic cell cycle
0.63	GO:0032467	positive regulation of cytokinesis
0.59	GO:0045860	positive regulation of protein kinase activity
0.50	GO:0006468	protein phosphorylation
0.48	GO:0051301	cell division
0.47	GO:0009794	regulation of mitotic cell cycle, embryonic

0.75	GO:0004725	protein tyrosine phosphatase activity
0.62	GO:0019901	protein kinase binding
0.44	GO:0051087	chaperone binding

0.60	GO:0000922	spindle pole
0.59	GO:0005813	centrosome
0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm

0.75

GO:0004725

sp|P48973|CXL10_RAT
C-X-C motif chemokine 10
Search

CXCL10

0.79	C-X-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:1901740	negative regulation of myoblast fusion
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.73	GO:1901509	regulation of endothelial tube morphogenesis
0.72	GO:0006952	defense response
0.72	GO:0043950	positive regulation of cAMP-mediated signaling
0.71	GO:0072678	T cell migration
0.71	GO:0010819	regulation of T cell chemotaxis
0.71	GO:0042118	endothelial cell activation

0.84	GO:0008009	chemokine activity
0.74	GO:0048248	CXCR3 chemokine receptor binding
0.65	GO:0008201	heparin binding
0.37	GO:0008603	cAMP-dependent protein kinase regulator activity

0.72	GO:0005615	extracellular space
0.65	GO:0009897	external side of plasma membrane

sp|P48974|V1BR_RAT
Vasopressin V1b receptor
Search

AVPR1B

0.92	Pituitary vasotocin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0001992	regulation of systemic arterial blood pressure by vasopressin
0.51	GO:0045907	positive regulation of vasoconstriction
0.49	GO:1901652	response to peptide
0.47	GO:0009725	response to hormone
0.46	GO:0071495	cellular response to endogenous stimulus
0.46	GO:0071310	cellular response to organic substance
0.40	GO:0043270	positive regulation of ion transport
0.39	GO:0032849	positive regulation of cellular pH reduction
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.85	GO:0005000	vasopressin receptor activity
0.48	GO:0042277	peptide binding
0.42	GO:0004990	oxytocin receptor activity
0.38	GO:0042562	hormone binding
0.36	GO:0031894	V1A vasopressin receptor binding
0.35	GO:0005080	protein kinase C binding
0.35	GO:0042803	protein homodimerization activity

0.54	GO:0005886	plasma membrane
0.38	GO:0043204	perikaryon
0.36	GO:0031410	cytoplasmic vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0043005	neuron projection
0.33	GO:0012506	vesicle membrane
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P48998|INVO_RAT
Involucrin
Search

IVL

0.95	Involucrin

0.85	GO:0030216	keratinocyte differentiation
0.46	GO:0010224	response to UV-B
0.45	GO:0018149	peptide cross-linking

0.44	GO:0030674	protein binding, bridging
0.39	GO:0005198	structural molecule activity

0.85	GO:0001533	cornified envelope
0.44	GO:0070062	extracellular exosome
0.41	GO:0005737	cytoplasm

sp|P49000|MIS_RAT
Muellerian-inhibiting factor
Search

AMH

0.87	Muellerian-inhibiting factor

0.83	GO:0008406	gonad development
0.77	GO:0001880	Mullerian duct regression
0.76	GO:0010469	regulation of receptor activity
0.66	GO:0007498	mesoderm development
0.66	GO:0060485	mesenchyme development
0.65	GO:0001655	urogenital system development
0.60	GO:0007267	cell-cell signaling
0.60	GO:2000355	negative regulation of ovarian follicle development
0.59	GO:0048162	multi-layer follicle stage
0.56	GO:0010628	positive regulation of gene expression

0.78	GO:0008083	growth factor activity
0.63	GO:0005179	hormone activity
0.61	GO:0005160	transforming growth factor beta receptor binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus

sp|P49001|BMP2_RAT
Bone morphogenetic protein 2
Search

BMP2

0.74	Bone morphogenetic protein 2-A

0.75	GO:0010469	regulation of receptor activity
0.62	GO:0003134	endodermal-mesodermal cell signaling involved in heart induction
0.61	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development
0.61	GO:0035630	bone mineralization involved in bone maturation
0.60	GO:0051042	negative regulation of calcium-independent cell-cell adhesion
0.60	GO:2000726	negative regulation of cardiac muscle cell differentiation
0.60	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.59	GO:0060395	SMAD protein signal transduction
0.59	GO:0032345	negative regulation of aldosterone metabolic process
0.59	GO:2000065	negative regulation of cortisol biosynthetic process

0.78	GO:0008083	growth factor activity
0.61	GO:0070700	BMP receptor binding
0.58	GO:0039706	co-receptor binding
0.57	GO:0046332	SMAD binding
0.57	GO:0019211	phosphatase activator activity
0.56	GO:0004745	retinol dehydrogenase activity
0.50	GO:0046982	protein heterodimerization activity
0.47	GO:0005125	cytokine activity
0.47	GO:0005160	transforming growth factor beta receptor binding
0.34	GO:0019904	protein domain specific binding

0.66	GO:0005576	extracellular region
0.59	GO:0070724	BMP receptor complex
0.53	GO:0009986	cell surface
0.42	GO:0043227	membrane-bounded organelle
0.40	GO:0043229	intracellular organelle
0.33	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm

0.56

GO:0004745

sp|P49002|BMP3_RAT
Bone morphogenetic protein 3
Search

BMP3

0.96	Bone morphogenetic protein 3

0.74	GO:0010469	regulation of receptor activity
0.72	GO:0001649	osteoblast differentiation
0.53	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.50	GO:0060395	SMAD protein signal transduction
0.49	GO:0030509	BMP signaling pathway
0.47	GO:0043408	regulation of MAPK cascade
0.46	GO:0048856	anatomical structure development
0.45	GO:0042981	regulation of apoptotic process
0.44	GO:0045668	negative regulation of osteoblast differentiation
0.43	GO:0045444	fat cell differentiation

0.77	GO:0008083	growth factor activity
0.65	GO:0005125	cytokine activity
0.61	GO:0070700	BMP receptor binding
0.50	GO:0005160	transforming growth factor beta receptor binding
0.35	GO:0016015	morphogen activity

0.65	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|P49088|ASNS_RAT
Asparagine synthetase [glutamine-hydrolyzing]
Search

ASNS

0.63	Asparagine synthetase

0.75	GO:0006529	asparagine biosynthetic process
0.66	GO:0006541	glutamine metabolic process
0.56	GO:0042149	cellular response to glucose starvation
0.54	GO:0045931	positive regulation of mitotic cell cycle
0.52	GO:0043066	negative regulation of apoptotic process
0.43	GO:0070982	L-asparagine metabolic process
0.40	GO:0031427	response to methotrexate
0.39	GO:0032354	response to follicle-stimulating hormone
0.38	GO:0001889	liver development
0.38	GO:0043200	response to amino acid

0.75	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity
0.53	GO:0005524	ATP binding
0.44	GO:0042803	protein homodimerization activity
0.34	GO:0048037	cofactor binding

0.48

GO:0005829

cytosol

0.75

EC:6.3.5.4

GO:0004066

sp|P49134|ITB1_RAT
Integrin beta-1
Search

ITGB1

0.67	Integrin beta

0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0010710	regulation of collagen catabolic process
0.58	GO:0033627	cell adhesion mediated by integrin
0.57	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.57	GO:1903078	positive regulation of protein localization to plasma membrane
0.56	GO:0021943	formation of radial glial scaffolds
0.56	GO:2000811	negative regulation of anoikis
0.56	GO:0050901	leukocyte tethering or rolling
0.56	GO:0031623	receptor internalization

0.65	GO:0004872	receptor activity
0.58	GO:0001968	fibronectin binding
0.57	GO:0019960	C-X3-C chemokine binding
0.57	GO:0098639	collagen binding involved in cell-matrix adhesion
0.54	GO:0043236	laminin binding
0.54	GO:0002020	protease binding
0.53	GO:0046982	protein heterodimerization activity
0.52	GO:0005178	integrin binding
0.52	GO:0045296	cadherin binding
0.49	GO:0003779	actin binding

0.81	GO:0008305	integrin complex
0.60	GO:0071438	invadopodium membrane
0.57	GO:0032587	ruffle membrane
0.55	GO:0035748	myelin sheath abaxonal region
0.55	GO:0005925	focal adhesion
0.54	GO:0042383	sarcolemma
0.54	GO:0031594	neuromuscular junction
0.54	GO:0030175	filopodium
0.53	GO:0014704	intercalated disc
0.53	GO:0043197	dendritic spine

sp|P49185|MK08_RAT
Mitogen-activated protein kinase 8
Search

MAPK8

0.58	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.57	GO:1902595	regulation of DNA replication origin binding
0.56	GO:0090045	positive regulation of deacetylase activity
0.55	GO:0031098	stress-activated protein kinase signaling cascade
0.54	GO:0031063	regulation of histone deacetylation
0.54	GO:0031281	positive regulation of cyclase activity
0.54	GO:0071276	cellular response to cadmium ion
0.53	GO:0034198	cellular response to amino acid starvation
0.53	GO:0009612	response to mechanical stimulus
0.53	GO:0032091	negative regulation of protein binding

0.81	GO:0004707	MAP kinase activity
0.57	GO:0035033	histone deacetylase regulator activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.53	GO:0042826	histone deacetylase binding
0.35	GO:0019894	kinesin binding

0.45	GO:0005622	intracellular
0.44	GO:0043005	neuron projection
0.42	GO:0043227	membrane-bounded organelle
0.37	GO:0036477	somatodendritic compartment
0.36	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0044297	cell body
0.34	GO:0044422	organelle part
0.33	GO:0043234	protein complex
0.33	GO:0043228	non-membrane-bounded organelle

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P49186|MK09_RAT
Mitogen-activated protein kinase 9
Search

MAPK9

0.59	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.59	GO:0071276	cellular response to cadmium ion
0.58	GO:0061833	protein localization to tricellular tight junction
0.57	GO:0031098	stress-activated protein kinase signaling cascade
0.57	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.56	GO:0018105	peptidyl-serine phosphorylation
0.56	GO:0071803	positive regulation of podosome assembly
0.53	GO:2001235	positive regulation of apoptotic signaling pathway
0.53	GO:0034614	cellular response to reactive oxygen species
0.53	GO:0042752	regulation of circadian rhythm

0.81	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0008134	transcription factor binding
0.47	GO:0035033	histone deacetylase regulator activity
0.44	GO:0042826	histone deacetylase binding
0.35	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.35	GO:0031435	mitogen-activated protein kinase kinase kinase binding

0.46	GO:0005829	cytosol
0.45	GO:0043005	neuron projection
0.43	GO:0005739	mitochondrion
0.42	GO:0005634	nucleus
0.35	GO:0043204	perikaryon
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P49187|MK10_RAT
Mitogen-activated protein kinase 10
Search

MAPK10

0.58	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.47	GO:0007399	nervous system development
0.46	GO:0031098	stress-activated protein kinase signaling cascade
0.45	GO:0001889	liver development
0.43	GO:0048468	cell development
0.38	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0042752	regulation of circadian rhythm
0.37	GO:0048511	rhythmic process
0.36	GO:0009416	response to light stimulus
0.36	GO:0007626	locomotory behavior

0.81	GO:0004707	MAP kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004708	MAP kinase kinase activity
0.35	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.44	GO:0043005	neuron projection
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0014069	postsynaptic density
0.35	GO:0043204	perikaryon
0.34	GO:0005886	plasma membrane
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044422	organelle part

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P49192|CART_RAT
Cocaine- and amphetamine-regulated transcript protein
Search

CARTPT

0.97	Cocaine-and amphetamine-regulated transcript

0.86	GO:0032099	negative regulation of appetite
0.86	GO:0008343	adult feeding behavior
0.84	GO:0000186	activation of MAPKK activity
0.82	GO:0001678	cellular glucose homeostasis
0.78	GO:0009267	cellular response to starvation
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0032812	positive regulation of epinephrine secretion
0.63	GO:0051971	positive regulation of transmission of nerve impulse
0.62	GO:0045779	negative regulation of bone resorption
0.61	GO:0045777	positive regulation of blood pressure

0.50

GO:0005184

neuropeptide hormone activity

0.73	GO:0005615	extracellular space
0.57	GO:0030141	secretory granule
0.30	GO:0016020	membrane

sp|P49218|MTR1A_RAT
Melatonin receptor type 1A (Fragment)
Search

MTNR1A

0.84	Melatonin receptor type 1A

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0030828	positive regulation of cGMP biosynthetic process
0.45	GO:0007623	circadian rhythm
0.37	GO:0051051	negative regulation of transport
0.37	GO:0045820	negative regulation of glycolytic process
0.36	GO:0046324	regulation of glucose import
0.35	GO:0050796	regulation of insulin secretion
0.34	GO:0007617	mating behavior
0.34	GO:1904950	negative regulation of establishment of protein localization
0.34	GO:0043010	camera-type eye development

0.85	GO:0008502	melatonin receptor activity
0.53	GO:0042562	hormone binding
0.36	GO:0097159	organic cyclic compound binding
0.35	GO:0031784	melatonin receptor binding
0.35	GO:0033218	amide binding
0.33	GO:0008144	drug binding
0.32	GO:1901363	heterocyclic compound binding

0.50	GO:0043235	receptor complex
0.45	GO:0005887	integral component of plasma membrane
0.34	GO:0043025	neuronal cell body

sp|P49242|RS3A_RAT
40S ribosomal protein S3a
Search

sp|P49287|MTR1B_RAT
Melatonin receptor type 1B (Fragment)
Search

0.87	Melatonin receptor isoform 1 (Fragment)

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0030823	regulation of cGMP metabolic process
0.47	GO:0030804	positive regulation of cyclic nucleotide biosynthetic process
0.46	GO:1900373	positive regulation of purine nucleotide biosynthetic process
0.46	GO:0050796	regulation of insulin secretion
0.45	GO:0042593	glucose homeostasis
0.44	GO:0007623	circadian rhythm
0.37	GO:0090278	negative regulation of peptide hormone secretion
0.37	GO:0050709	negative regulation of protein secretion
0.36	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep

0.85	GO:0008502	melatonin receptor activity
0.46	GO:0042562	hormone binding
0.35	GO:0097159	organic cyclic compound binding
0.34	GO:0005515	protein binding

0.44	GO:0043235	receptor complex
0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0043025	neuronal cell body

sp|P49301|CLC10_RAT
C-type lectin domain family 10 member A
Search

0.94	Macrophage galactose N-acetyl-galactosamine-specific lectin 2

0.45	GO:0031668	cellular response to extracellular stimulus
0.45	GO:0055088	lipid homeostasis
0.44	GO:0031647	regulation of protein stability
0.43	GO:0009100	glycoprotein metabolic process
0.40	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.40	GO:0006897	endocytosis
0.37	GO:0030282	bone mineralization
0.36	GO:0018196	peptidyl-asparagine modification
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0043413	macromolecule glycosylation

0.69	GO:0030246	carbohydrate binding
0.47	GO:0042803	protein homodimerization activity
0.42	GO:0004873	asialoglycoprotein receptor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0051861	glycolipid binding
0.32	GO:0003676	nucleic acid binding
0.31	GO:0036094	small molecule binding

0.34	GO:0005886	plasma membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P49430|THAS_RAT
Thromboxane-A synthase
Search

TBXAS1

0.96	Thromboxane-A synthase

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0046457	prostanoid biosynthetic process
0.44	GO:0006693	prostaglandin metabolic process
0.40	GO:0030644	cellular chloride ion homeostasis
0.39	GO:0045907	positive regulation of vasoconstriction
0.39	GO:0070542	response to fatty acid
0.39	GO:0045471	response to ethanol
0.37	GO:0042448	progesterone metabolic process
0.36	GO:0006704	glucocorticoid biosynthetic process
0.36	GO:0019369	arachidonic acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.62	GO:0004796	thromboxane-A synthase activity
0.38	GO:0036134	12-hydroxyheptadecatrienoic acid synthase activity
0.37	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity

0.41	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0043025	neuronal cell body
0.35	GO:0030424	axon
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.68	EC:1.14	GO:0016705
0.62	KEGG:R02268	GO:0004796

sp|P49432|ODPB_RAT
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Search

PDHB

0.55	Mitochondrial pyruvate dehydrogenase e1 component subunit beta

0.58	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.51	GO:0006099	tricarboxylic acid cycle
0.46	GO:0043473	pigmentation
0.40	GO:0019362	pyridine nucleotide metabolic process
0.40	GO:0005975	carbohydrate metabolic process
0.40	GO:0006757	ATP generation from ADP
0.38	GO:1901575	organic substance catabolic process
0.36	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate

0.62	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.47	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity
0.34	GO:0005515	protein binding

0.55	GO:0045254	pyruvate dehydrogenase complex
0.51	GO:0031974	membrane-enclosed lumen
0.49	GO:0044428	nuclear part
0.47	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome

0.62	EC:1.2.1	GO:0034604
0.62	KEGG:R00209	GO:0034604

sp|P49445|PTN7_RAT
Tyrosine-protein phosphatase non-receptor type 7
Search

PTPN7

0.97	LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 7

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.41	GO:0038128	ERBB2 signaling pathway
0.40	GO:0010633	negative regulation of epithelial cell migration
0.40	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.36	GO:0071345	cellular response to cytokine stimulus

0.73	GO:0004725	protein tyrosine phosphatase activity
0.45	GO:0001784	phosphotyrosine residue binding
0.37	GO:0019901	protein kinase binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity

0.53	GO:0009898	cytoplasmic side of plasma membrane
0.50	GO:0005829	cytosol
0.38	GO:0030054	cell junction
0.37	GO:0005856	cytoskeleton
0.35	GO:0005654	nucleoplasm
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.73

GO:0004725

sp|P49616|UPAR_RAT
Urokinase plasminogen activator surface receptor
Search

PLAUR

0.97	Urokinase plasminogen activator surface receptor

0.87	GO:0038195	urokinase plasminogen activator signaling pathway
0.74	GO:0030162	regulation of proteolysis
0.70	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.69	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.68	GO:0043388	positive regulation of DNA binding
0.67	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.62	GO:0001934	positive regulation of protein phosphorylation
0.60	GO:0051346	negative regulation of hydrolase activity
0.58	GO:0032269	negative regulation of cellular protein metabolic process
0.47	GO:0016310	phosphorylation

0.87	GO:0030377	urokinase plasminogen activator receptor activity
0.61	GO:0019904	protein domain specific binding
0.59	GO:0005102	receptor binding
0.58	GO:0019899	enzyme binding
0.49	GO:0016301	kinase activity

0.61	GO:0009986	cell surface
0.55	GO:0005887	integral component of plasma membrane
0.50	GO:0031225	anchored component of membrane
0.48	GO:0071438	invadopodium membrane
0.46	GO:0030054	cell junction
0.41	GO:0070062	extracellular exosome
0.39	GO:0045177	apical part of cell
0.39	GO:0035579	specific granule membrane
0.38	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0019898	extrinsic component of membrane

sp|P49620|DGKG_RAT
Diacylglycerol kinase gamma
Search

DGKG

0.47	Diacylglycerol kinase gamma

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.51	GO:0030258	lipid modification
0.50	GO:0046486	glycerolipid metabolic process
0.39	GO:0048666	neuron development
0.36	GO:0030168	platelet activation
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.80	GO:0004143	diacylglycerol kinase activity
0.75	GO:0003951	NAD+ kinase activity
0.69	GO:0005509	calcium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane
0.33	GO:0043227	membrane-bounded organelle

0.80	EC:2.7.1.107	GO:0004143
0.75	KEGG:R00104	GO:0003951

sp|P49621|DGKB_RAT
Diacylglycerol kinase beta
Search

DGKB

0.49	Diacylglycerol kinase beta

0.79	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.48	GO:0030258	lipid modification
0.47	GO:0046486	glycerolipid metabolic process
0.35	GO:0030168	platelet activation

0.79	GO:0004143	diacylglycerol kinase activity
0.74	GO:0003951	NAD+ kinase activity
0.69	GO:0005509	calcium ion binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.41	GO:0005886	plasma membrane
0.34	GO:0043227	membrane-bounded organelle

0.79	EC:2.7.1.107	GO:0004143
0.74	KEGG:R00104	GO:0003951

sp|P49651|P2RY1_RAT
P2Y purinoceptor 1
Search

P2RY1

0.97	Purinergic receptor P2Y, G-protein coupled 1

0.83	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.80	GO:0090075	relaxation of muscle
0.78	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.76	GO:0030168	platelet activation
0.55	GO:0051050	positive regulation of transport
0.54	GO:0071407	cellular response to organic cyclic compound
0.52	GO:0043269	regulation of ion transport
0.47	GO:0030321	transepithelial chloride transport
0.44	GO:0097746	regulation of blood vessel diameter
0.43	GO:0051046	regulation of secretion

0.83	GO:0001608	G-protein coupled nucleotide receptor activity
0.81	GO:0001614	purinergic nucleotide receptor activity
0.42	GO:0045031	ATP-activated adenosine receptor activity
0.42	GO:0045032	ADP-activated adenosine receptor activity
0.42	GO:0031686	A1 adenosine receptor binding
0.40	GO:0097110	scaffold protein binding
0.38	GO:0043531	ADP binding
0.38	GO:0045125	bioactive lipid receptor activity
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0015057	thrombin-activated receptor activity

0.43	GO:0005886	plasma membrane
0.40	GO:0045177	apical part of cell
0.39	GO:0014069	postsynaptic density
0.38	GO:0030425	dendrite
0.38	GO:0044297	cell body
0.36	GO:0009986	cell surface
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.32

GO:0008233

sp|P49653|P2RX2_RAT
P2X purinoceptor 2
Search

sp|P49654|P2RX3_RAT
P2X purinoceptor 3
Search

0.85	GO:0033198	response to ATP
0.85	GO:0035590	purinergic nucleotide receptor signaling pathway
0.80	GO:0060079	excitatory postsynaptic potential
0.61	GO:0098655	cation transmembrane transport
0.61	GO:0030432	peristalsis
0.60	GO:0014832	urinary bladder smooth muscle contraction
0.60	GO:0048266	behavioral response to pain
0.58	GO:0007274	neuromuscular synaptic transmission
0.57	GO:0048167	regulation of synaptic plasticity
0.57	GO:0009612	response to mechanical stimulus

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.85	GO:0001614	purinergic nucleotide receptor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.38	GO:0019103	pyrimidine nucleotide binding
0.37	GO:0099604	ligand-gated calcium channel activity
0.37	GO:0045296	cadherin binding
0.34	GO:0004930	G-protein coupled receptor activity

0.78	GO:0098794	postsynapse
0.67	GO:0005887	integral component of plasma membrane
0.55	GO:0030424	axon
0.54	GO:0043235	receptor complex
0.51	GO:0005639	integral component of nuclear inner membrane
0.39	GO:0044309	neuron spine
0.39	GO:0043679	axon terminus
0.39	GO:0005791	rough endoplasmic reticulum
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite

sp|P49655|KCJ10_RAT
ATP-sensitive inward rectifier potassium channel 10
Search

KCNJ10

0.96	Potassium inwardly-rectifying channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.57	GO:0051933	amino acid neurotransmitter reuptake
0.56	GO:0060075	regulation of resting membrane potential
0.56	GO:0098712	L-glutamate import across plasma membrane
0.55	GO:0022010	central nervous system myelination
0.55	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.54	GO:0007628	adult walking behavior
0.53	GO:0055075	potassium ion homeostasis

0.84	GO:0005242	inward rectifier potassium channel activity
0.35	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0016323	basolateral plasma membrane
0.50	GO:0098793	presynapse
0.42	GO:0005887	integral component of plasma membrane
0.36	GO:0097449	astrocyte projection
0.35	GO:0005902	microvillus
0.35	GO:0016324	apical plasma membrane

sp|P49684|UR2R_RAT
Urotensin-2 receptor
Search

UTS2R

0.97	Urotensin II receptor

0.83	GO:0008217	regulation of blood pressure
0.82	GO:0097746	regulation of blood vessel diameter
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep
0.42	GO:0035814	negative regulation of renal sodium excretion
0.42	GO:0035811	negative regulation of urine volume
0.42	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness
0.40	GO:0048146	positive regulation of fibroblast proliferation
0.40	GO:1903524	positive regulation of blood circulation
0.40	GO:0045766	positive regulation of angiogenesis

0.86

GO:0001604

urotensin II receptor activity

0.43	GO:0005887	integral component of plasma membrane
0.40	GO:0055037	recycling endosome
0.39	GO:0005769	early endosome
0.33	GO:0005681	spliceosomal complex

sp|P49743|RXRB_RAT
Retinoic acid receptor RXR-beta (Fragment)
Search

RXRB

0.97	Retinoid X nuclear receptor beta

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0030522	intracellular receptor signaling pathway
0.50	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process
0.39	GO:0060038	cardiac muscle cell proliferation

0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.38	GO:0042809	vitamin D receptor binding
0.37	GO:0035326	enhancer binding
0.36	GO:0050692	DBD domain binding
0.36	GO:0050693	LBD domain binding

0.61	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0043235	receptor complex
0.35	GO:0005581	collagen trimer
0.35	GO:0005667	transcription factor complex
0.34	GO:0000785	chromatin
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|P49744|TSP4_RAT
Thrombospondin-4
Search

THBS4

0.97	thrombospondin-4-B

0.81	GO:0030198	extracellular matrix organization
0.72	GO:0007155	cell adhesion
0.63	GO:0051451	myoblast migration
0.62	GO:0048266	behavioral response to pain
0.62	GO:0090023	positive regulation of neutrophil chemotaxis
0.61	GO:0034103	regulation of tissue remodeling
0.60	GO:0001938	positive regulation of endothelial cell proliferation
0.59	GO:0016525	negative regulation of angiogenesis
0.59	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.57	GO:0034976	response to endoplasmic reticulum stress

0.70	GO:0005509	calcium ion binding
0.60	GO:0008201	heparin binding
0.60	GO:0005178	integrin binding
0.42	GO:0005518	collagen binding
0.41	GO:0043395	heparan sulfate proteoglycan binding
0.41	GO:0002020	protease binding
0.40	GO:0008083	growth factor activity
0.37	GO:0043237	laminin-1 binding
0.36	GO:0001968	fibronectin binding

0.74	GO:0031012	extracellular matrix
0.60	GO:0016529	sarcoplasmic reticulum
0.55	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0031594	neuromuscular junction

sp|P49745|TPO_RAT
Thrombopoietin
Search

THPO

0.97	Thrombopoietin

0.80	GO:0008283	cell proliferation
0.77	GO:0038163	thrombopoietin-mediated signaling pathway
0.76	GO:0045654	positive regulation of megakaryocyte differentiation
0.76	GO:0010469	regulation of receptor activity
0.75	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.71	GO:0051897	positive regulation of protein kinase B signaling
0.69	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.68	GO:0030099	myeloid cell differentiation
0.40	GO:0071222	cellular response to lipopolysaccharide

0.81	GO:0005125	cytokine activity
0.79	GO:0005179	hormone activity
0.38	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

sp|P49791|NU153_RAT
Nuclear pore complex protein Nup153
Search

NUP153

0.70	Nucleoporin 153

0.66	GO:0046832	negative regulation of RNA export from nucleus
0.63	GO:0051292	nuclear pore complex assembly
0.58	GO:0006913	nucleocytoplasmic transport
0.51	GO:0001525	angiogenesis
0.51	GO:0034504	protein localization to nucleus
0.49	GO:0017038	protein import
0.48	GO:0051236	establishment of RNA localization
0.48	GO:0050657	nucleic acid transport
0.48	GO:0072594	establishment of protein localization to organelle

0.80	GO:0017056	structural constituent of nuclear pore
0.63	GO:0043495	protein membrane anchor
0.55	GO:0042802	identical protein binding
0.53	GO:0046872	metal ion binding
0.53	GO:0008139	nuclear localization sequence binding

0.69	GO:0044615	nuclear pore nuclear basket
0.63	GO:0042405	nuclear inclusion body
0.59	GO:0034399	nuclear periphery
0.58	GO:0031965	nuclear membrane
0.54	GO:0005730	nucleolus
0.54	GO:0044613	nuclear pore central transport channel
0.52	GO:0005829	cytosol

sp|P49793|NUP98_RAT
Nuclear pore complex protein Nup98-Nup96
Search

NUP98

0.74	Nuclear pore complex protein Nup98-Nup96

0.72	GO:0006913	nucleocytoplasmic transport
0.51	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.51	GO:0051292	nuclear pore complex assembly
0.46	GO:0006366	transcription by RNA polymerase II
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
0.44	GO:0034398	telomere tethering at nuclear periphery
0.43	GO:0051236	establishment of RNA localization
0.43	GO:0050657	nucleic acid transport
0.43	GO:0006260	DNA replication

0.80	GO:0017056	structural constituent of nuclear pore
0.50	GO:1990841	promoter-specific chromatin binding
0.50	GO:0001105	RNA polymerase II transcription coactivator activity
0.46	GO:0003729	mRNA binding
0.44	GO:0008139	nuclear localization sequence binding
0.35	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.33	GO:0022835	transmitter-gated channel activity
0.33	GO:0140135	mechanosensitive cation channel activity
0.33	GO:0018024	histone-lysine N-methyltransferase activity

0.78	GO:0005643	nuclear pore
0.51	GO:0042405	nuclear inclusion body
0.48	GO:0034399	nuclear periphery
0.48	GO:0031965	nuclear membrane
0.47	GO:0000776	kinetochore
0.47	GO:0016604	nuclear body
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0045211	postsynaptic membrane
0.33	GO:0030054	cell junction
0.31	GO:0005829	cytosol

0.33

EC:2.1.1.43

GO:0018024

sp|P49797|RGS3_RAT
Regulator of G-protein signaling 3
Search

0.73	Regulator of G-protein signaling 3

0.59	GO:0043547	positive regulation of GTPase activity
0.53	GO:0009968	negative regulation of signal transduction
0.46	GO:0007340	acrosome reaction
0.46	GO:0023052	signaling
0.46	GO:0007154	cell communication
0.44	GO:0051716	cellular response to stimulus
0.42	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.42	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.41	GO:0043405	regulation of MAP kinase activity
0.40	GO:0018105	peptidyl-serine phosphorylation

0.59	GO:0005096	GTPase activator activity
0.39	GO:0005515	protein binding
0.38	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.37	GO:0005544	calcium-dependent phospholipid binding
0.35	GO:0005509	calcium ion binding

0.64	GO:0005654	nucleoplasm
0.63	GO:0005829	cytosol
0.47	GO:0005886	plasma membrane
0.37	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

0.38

GO:0004674

sp|P49799|RGS4_RAT
Regulator of G-protein signaling 4
Search

RGS4

0.97	LOW QUALITY PROTEIN: regulator of G-protein signaling 4

0.72	GO:0043547	positive regulation of GTPase activity
0.66	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.44	GO:0009968	negative regulation of signal transduction
0.39	GO:0031018	endocrine pancreas development
0.39	GO:0007626	locomotory behavior
0.38	GO:0007409	axonogenesis
0.36	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.35	GO:0043405	regulation of MAP kinase activity
0.34	GO:0010519	negative regulation of phospholipase activity

0.73	GO:0005096	GTPase activator activity
0.40	GO:0001965	G-protein alpha-subunit binding
0.35	GO:0005516	calmodulin binding

0.45	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.39	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0019898	extrinsic component of membrane

sp|P49800|RGS5_RAT
Regulator of G-protein signaling 5
Search

RGS5

0.96	Regulator of G-protein signaling 5

0.64	GO:0043547	positive regulation of GTPase activity
0.52	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0009968	negative regulation of signal transduction
0.43	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.36	GO:0007601	visual perception

0.65	GO:0005096	GTPase activator activity
0.36	GO:0005516	calmodulin binding

0.61	GO:0005829	cytosol
0.47	GO:0005886	plasma membrane
0.36	GO:0045121	membrane raft
0.30	GO:0031224	intrinsic component of membrane

sp|P49801|RGS6_RAT
Regulator of G-protein signaling 6 (Fragment)
Search

0.73	Regulator of G-protein signalling 6 (Fragment)

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0043547	positive regulation of GTPase activity
0.54	GO:0035556	intracellular signal transduction

0.64	GO:0005096	GTPase activator activity
0.64	GO:0004871	signal transducer activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex

sp|P49803|RGS7_RAT
Regulator of G-protein signaling 7
Search

RGS7

0.93	Regulator of G-protein signalling 7

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0035556	intracellular signal transduction
0.50	GO:0043547	positive regulation of GTPase activity
0.37	GO:0009968	negative regulation of signal transduction
0.37	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006457	protein folding

0.63	GO:0004871	signal transducer activity
0.55	GO:0031681	G-protein beta-subunit binding
0.50	GO:0005096	GTPase activator activity

0.80	GO:0005834	heterotrimeric G-protein complex
0.46	GO:0005829	cytosol
0.37	GO:0044292	dendrite terminus
0.34	GO:0005634	nucleus

sp|P49804|RGS8_RAT
Regulator of G-protein signaling 8
Search

RGS8

0.97	Regulator of G-protein signaling 8

0.70	GO:0043547	positive regulation of GTPase activity
0.66	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0060159	regulation of dopamine receptor signaling pathway
0.39	GO:0009968	negative regulation of signal transduction
0.39	GO:0095500	acetylcholine receptor signaling pathway
0.34	GO:0008591	regulation of Wnt signaling pathway, calcium modulating pathway
0.34	GO:0061053	somite development
0.33	GO:0007601	visual perception

0.70	GO:0005096	GTPase activator activity
0.35	GO:0001965	G-protein alpha-subunit binding
0.33	GO:0005516	calmodulin binding

0.40	GO:0032809	neuronal cell body membrane
0.39	GO:0043204	perikaryon
0.38	GO:0030425	dendrite
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.33	GO:0045121	membrane raft
0.30	GO:0031224	intrinsic component of membrane

sp|P49805|RGS9_RAT
Regulator of G-protein signaling 9
Search

RGS9

0.94	Regulator of G-protein signaling 9

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.46	GO:0043547	positive regulation of GTPase activity
0.40	GO:0007601	visual perception
0.40	GO:0043627	response to estrogen
0.40	GO:0009968	negative regulation of signal transduction
0.40	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.38	GO:0007399	nervous system development
0.34	GO:0006457	protein folding

0.63	GO:0004871	signal transducer activity
0.46	GO:0005096	GTPase activator activity
0.38	GO:0032403	protein complex binding
0.37	GO:0031681	G-protein beta-subunit binding

0.80	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.58	GO:0001917	photoreceptor inner segment
0.57	GO:0001750	photoreceptor outer segment
0.38	GO:0060170	ciliary membrane
0.37	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.34	GO:0044292	dendrite terminus
0.30	GO:0031224	intrinsic component of membrane

sp|P49806|RGS10_RAT
Regulator of G-protein signaling 10
Search

RGS10

0.97	Regulator of G-protein signalling 10

0.77	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.57	GO:0043547	positive regulation of GTPase activity
0.56	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.46	GO:0009968	negative regulation of signal transduction
0.37	GO:0010519	negative regulation of phospholipase activity
0.37	GO:0060087	relaxation of vascular smooth muscle
0.37	GO:0060452	positive regulation of cardiac muscle contraction
0.37	GO:0055119	relaxation of cardiac muscle
0.37	GO:0010614	negative regulation of cardiac muscle hypertrophy
0.37	GO:0043949	regulation of cAMP-mediated signaling

0.78	GO:0001965	G-protein alpha-subunit binding
0.61	GO:0030695	GTPase regulator activity
0.56	GO:0008047	enzyme activator activity
0.47	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.40	GO:0043197	dendritic spine
0.40	GO:0043679	axon terminus
0.40	GO:0043025	neuronal cell body
0.39	GO:0005886	plasma membrane
0.35	GO:0098562	cytoplasmic side of membrane

0.33

EC:2.7.7.7

GO:0003887

sp|P49807|RGS11_RAT
Regulator of G-protein signaling 11 (Fragment)
Search

0.79	Regulators of G protein signaling XRGSIV (Fragment)

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0035556	intracellular signal transduction
0.46	GO:0043547	positive regulation of GTPase activity
0.39	GO:0009968	negative regulation of signal transduction
0.39	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.37	GO:0007601	visual perception
0.37	GO:0043627	response to estrogen
0.35	GO:0007399	nervous system development
0.33	GO:0006457	protein folding

0.63	GO:0004871	signal transducer activity
0.51	GO:0031681	G-protein beta-subunit binding
0.46	GO:0005096	GTPase activator activity
0.36	GO:0032403	protein complex binding

0.80	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.50	GO:0001917	photoreceptor inner segment
0.50	GO:0001750	photoreceptor outer segment
0.37	GO:0044292	dendrite terminus
0.37	GO:0005737	cytoplasm
0.36	GO:0060170	ciliary membrane
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P49816|TSC2_RAT
Tuberin
Search

TSC2

0.83	Tuberous sclerosis 2

0.84	GO:0032007	negative regulation of TOR signaling
0.76	GO:0043547	positive regulation of GTPase activity
0.75	GO:0051056	regulation of small GTPase mediated signal transduction
0.68	GO:0043276	anoikis
0.64	GO:0016239	positive regulation of macroautophagy
0.51	GO:0046627	negative regulation of insulin receptor signaling pathway
0.51	GO:0051898	negative regulation of protein kinase B signaling
0.49	GO:0030178	negative regulation of Wnt signaling pathway
0.46	GO:0060575	intestinal epithelial cell differentiation
0.46	GO:0051726	regulation of cell cycle

0.76	GO:0005096	GTPase activator activity
0.63	GO:0019902	phosphatase binding
0.58	GO:0031267	small GTPase binding
0.58	GO:0042803	protein homodimerization activity

0.85	GO:0033596	TSC1-TSC2 complex
0.61	GO:0005634	nucleus
0.60	GO:0048471	perinuclear region of cytoplasm
0.60	GO:0005764	lysosome
0.56	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|P49864|GRAK_RAT
Granzyme K
Search

GZMK

0.84	Prostatic glandular kallikrein-6

0.61	GO:0006508	proteolysis
0.38	GO:0009405	pathogenesis
0.37	GO:0065008	regulation of biological quality
0.37	GO:0050817	coagulation
0.36	GO:0042060	wound healing
0.36	GO:0050819	negative regulation of coagulation
0.36	GO:0061045	negative regulation of wound healing
0.36	GO:0051604	protein maturation
0.35	GO:0008015	blood circulation
0.35	GO:0048518	positive regulation of biological process

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0090729	toxin activity
0.36	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.36	GO:0015035	protein disulfide oxidoreductase activity
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0009055	electron transfer activity
0.35	GO:0005509	calcium ion binding
0.33	GO:0008201	heparin binding
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0005057	signal transducer activity, downstream of receptor

0.41	GO:0005576	extracellular region
0.35	GO:0043234	protein complex
0.34	GO:0035578	azurophil granule lumen
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0005634	nucleus
0.32	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P49889|ST1E3_RAT
Estrogen sulfotransferase, isoform 3
Search

0.54	Estrogen sulfotransferase

0.85	GO:0006711	estrogen catabolic process
0.81	GO:0006068	ethanol catabolic process
0.80	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.77	GO:0045600	positive regulation of fat cell differentiation
0.74	GO:0051923	sulfation
0.72	GO:0007565	female pregnancy

0.88	GO:0004304	estrone sulfotransferase activity
0.86	GO:0050294	steroid sulfotransferase activity
0.85	GO:0047894	flavonol 3-sulfotransferase activity
0.83	GO:0005496	steroid binding
0.50	GO:0004062	aryl sulfotransferase activity
0.41	GO:0005515	protein binding

0.54	GO:0031965	nuclear membrane
0.49	GO:0005829	cytosol

0.88	EC:2.8.2.4	GO:0004304
0.85	KEGG:R02159	GO:0047894

sp|P49897|IOD3_RAT
Thyroxine 5-deiodinase
Search

DIO3

0.89	Thyroxine 5-deiodinase

0.76	GO:0042446	hormone biosynthetic process
0.71	GO:0042404	thyroid hormone catabolic process
0.66	GO:0046549	retinal cone cell development
0.64	GO:0040018	positive regulation of multicellular organism growth
0.58	GO:0006915	apoptotic process
0.55	GO:0070342	brown fat cell proliferation
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0006590	thyroid hormone generation
0.48	GO:0001666	response to hypoxia

0.86	GO:0004800	thyroxine 5'-deiodinase activity
0.72	GO:0033798	thyroxine 5-deiodinase activity

0.76	GO:0010008	endosome membrane
0.54	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.86

EC:1.97.1.10

GO:0004800

sp|P49911|AN32A_RAT
Acidic leucine-rich nuclear phosphoprotein 32 family member A
Search

ANP32A

0.91	Acidic leucine-rich nuclear phosphoprotein 32 family member A

0.71	GO:0006913	nucleocytoplasmic transport
0.69	GO:0043486	histone exchange
0.66	GO:0006334	nucleosome assembly
0.62	GO:0042981	regulation of apoptotic process
0.45	GO:0006351	transcription, DNA-templated
0.45	GO:0035067	negative regulation of histone acetylation
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.44	GO:0010977	negative regulation of neuron projection development

0.66	GO:0042393	histone binding
0.44	GO:0005178	integrin binding
0.44	GO:0008022	protein C-terminus binding
0.40	GO:0003723	RNA binding

0.74	GO:0048471	perinuclear region of cytoplasm
0.66	GO:0005783	endoplasmic reticulum
0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.40	GO:0005829	cytosol

sp|P49950|BCL2_RAT
Apoptosis regulator Bcl-2
Search

BCL2

0.87	3-ketodihydrosphingosine reductase

0.78	GO:0043066	negative regulation of apoptotic process
0.74	GO:0006915	apoptotic process
0.64	GO:0032848	negative regulation of cellular pH reduction
0.64	GO:0043375	CD8-positive, alpha-beta T cell lineage commitment
0.63	GO:0014042	positive regulation of neuron maturation
0.62	GO:0021747	cochlear nucleus development
0.62	GO:0002326	B cell lineage commitment
0.62	GO:0046671	negative regulation of retinal cell programmed cell death
0.62	GO:0045636	positive regulation of melanocyte differentiation
0.62	GO:0038034	signal transduction in absence of ligand

0.61	GO:0051434	BH3 domain binding
0.59	GO:0051721	protein phosphatase 2A binding
0.57	GO:0002020	protease binding
0.57	GO:0016248	channel inhibitor activity
0.54	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0042803	protein homodimerization activity
0.52	GO:0008134	transcription factor binding
0.49	GO:0022803	passive transmembrane transporter activity
0.47	GO:0043565	sequence-specific DNA binding

0.57	GO:0043209	myelin sheath
0.57	GO:0031965	nuclear membrane
0.56	GO:0005741	mitochondrial outer membrane
0.53	GO:0046930	pore complex
0.52	GO:0005789	endoplasmic reticulum membrane
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0097136	Bcl-2 family protein complex
0.33	GO:0005813	centrosome

0.31

GO:0016491

sp|P49952|WT1_RAT
Wilms tumor protein homolog
Search

WT1

0.97	Wilm's tumor suppressor-1

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0072112	glomerular visceral epithelial cell differentiation
0.52	GO:0061032	visceral serous pericardium development
0.50	GO:0030325	adrenal gland development
0.49	GO:0008285	negative regulation of cell proliferation
0.48	GO:0072284	metanephric S-shaped body morphogenesis
0.48	GO:0072299	negative regulation of metanephric glomerulus development
0.48	GO:2001076	positive regulation of metanephric ureteric bud development

0.50	GO:0044729	hemi-methylated DNA-binding
0.49	GO:0010385	double-stranded methylated DNA binding
0.44	GO:0070742	C2H2 zinc finger domain binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.41	GO:0043565	sequence-specific DNA binding
0.40	GO:0008270	zinc ion binding
0.39	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.50	GO:0005829	cytosol
0.46	GO:0044446	intracellular organelle part
0.36	GO:0043232	intracellular non-membrane-bounded organelle

sp|P50115|S10A8_RAT
Protein S100-A8
Search

S100A8

0.95	S100 calcium binding protein A8

0.81	GO:0050727	regulation of inflammatory response
0.78	GO:0045087	innate immune response
0.76	GO:0070488	neutrophil aggregation
0.74	GO:0018119	peptidyl-cysteine S-nitrosylation
0.73	GO:0002523	leukocyte migration involved in inflammatory response
0.70	GO:0030593	neutrophil chemotaxis
0.70	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.70	GO:0014002	astrocyte development
0.69	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.66	GO:0032103	positive regulation of response to external stimulus

0.86	GO:0035662	Toll-like receptor 4 binding
0.86	GO:0050544	arachidonic acid binding
0.86	GO:0050786	RAGE receptor binding
0.74	GO:0008017	microtubule binding
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding
0.40	GO:0048306	calcium-dependent protein binding

0.64	GO:0045111	intermediate filament cytoskeleton
0.60	GO:0005615	extracellular space
0.57	GO:0005829	cytosol

sp|P50116|S10A9_RAT
Protein S100-A9
Search

0.68	EF-HAND 2 containing protein

0.88	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.88	GO:0070488	neutrophil aggregation
0.87	GO:0045113	regulation of integrin biosynthetic process
0.86	GO:0002523	leukocyte migration involved in inflammatory response
0.86	GO:0014002	astrocyte development
0.86	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.85	GO:0030194	positive regulation of blood coagulation
0.85	GO:0030593	neutrophil chemotaxis
0.85	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.85	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process

0.87	GO:0035662	Toll-like receptor 4 binding
0.87	GO:0050544	arachidonic acid binding
0.86	GO:0050786	RAGE receptor binding
0.74	GO:0008017	microtubule binding
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding

0.75	GO:0030054	cell junction
0.73	GO:0005615	extracellular space
0.70	GO:0005654	nucleoplasm
0.68	GO:0005829	cytosol

sp|P50123|AMPE_RAT
Glutamyl aminopeptidase
Search

ENPEP

0.54	Glutamyl aminopeptidase

0.86	GO:0002003	angiotensin maturation
0.56	GO:0032835	glomerulus development
0.56	GO:0008283	cell proliferation
0.55	GO:0016477	cell migration
0.54	GO:0001525	angiogenesis
0.46	GO:0043171	peptide catabolic process
0.36	GO:0044266	multicellular organismal macromolecule catabolic process
0.36	GO:0044256	protein digestion
0.36	GO:0044268	multicellular organismal protein metabolic process
0.35	GO:0044243	multicellular organismal catabolic process

0.76	GO:0070006	metalloaminopeptidase activity
0.63	GO:0008270	zinc ion binding
0.46	GO:0042277	peptide binding

0.55	GO:0005903	brush border
0.54	GO:0009897	external side of plasma membrane
0.54	GO:0016324	apical plasma membrane
0.49	GO:0031410	cytoplasmic vesicle
0.47	GO:0005765	lysosomal membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0031983	vesicle lumen
0.35	GO:0012506	vesicle membrane
0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005789	endoplasmic reticulum membrane

sp|P50137|TKT_RAT
Transketolase
Search

TKT

0.46	Transketolase

0.57	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.51	GO:0040008	regulation of growth
0.37	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.36	GO:0009052	pentose-phosphate shunt, non-oxidative branch
0.36	GO:0005999	xylulose biosynthetic process
0.36	GO:0043085	positive regulation of catalytic activity
0.33	GO:0046390	ribose phosphate biosynthetic process

0.53	GO:0004802	transketolase activity
0.50	GO:0042803	protein homodimerization activity
0.41	GO:0048037	cofactor binding
0.36	GO:0008047	enzyme activator activity
0.35	GO:0046872	metal ion binding
0.34	GO:0048029	monosaccharide binding
0.34	GO:1901681	sulfur compound binding
0.33	GO:0019842	vitamin binding
0.32	GO:0043168	anion binding
0.32	GO:1901363	heterocyclic compound binding

0.53	GO:0043209	myelin sheath
0.52	GO:0016607	nuclear speck
0.36	GO:0070062	extracellular exosome
0.36	GO:0042579	microbody
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol

0.53

EC:2.2.1.1

GO:0004802

sp|P50169|RDH3_RAT
Retinol dehydrogenase 3
Search

0.94	Retinol dehydrogenase similar protein 2

0.51	GO:0055114	oxidation-reduction process
0.49	GO:0001523	retinoid metabolic process
0.44	GO:0034754	cellular hormone metabolic process
0.42	GO:0008202	steroid metabolic process
0.42	GO:0016102	diterpenoid biosynthetic process
0.40	GO:0034308	primary alcohol metabolic process
0.38	GO:0072330	monocarboxylic acid biosynthetic process
0.38	GO:0035138	pectoral fin morphogenesis
0.37	GO:0031017	exocrine pancreas development
0.37	GO:0035050	embryonic heart tube development

0.58	GO:0004745	retinol dehydrogenase activity
0.43	GO:0016229	steroid dehydrogenase activity
0.36	GO:0042803	protein homodimerization activity
0.34	GO:0009055	electron transfer activity

0.40	GO:0005783	endoplasmic reticulum
0.39	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0005829	cytosol
0.37	GO:0031090	organelle membrane
0.36	GO:0005634	nucleus
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0005769	early endosome
0.35	GO:0098805	whole membrane

0.58

GO:0004745

sp|P50170|RDH2_RAT
Retinol dehydrogenase 2
Search

0.93	Retinol dehydrogenase similar protein 2

0.51	GO:0055114	oxidation-reduction process
0.49	GO:0001523	retinoid metabolic process
0.44	GO:0034754	cellular hormone metabolic process
0.43	GO:0008202	steroid metabolic process
0.43	GO:0016102	diterpenoid biosynthetic process
0.39	GO:0034308	primary alcohol metabolic process
0.38	GO:0072330	monocarboxylic acid biosynthetic process
0.37	GO:0017144	drug metabolic process
0.35	GO:0035118	embryonic pectoral fin morphogenesis
0.35	GO:0031017	exocrine pancreas development

0.57	GO:0004745	retinol dehydrogenase activity
0.44	GO:0016229	steroid dehydrogenase activity
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0009055	electron transfer activity

0.40	GO:0005783	endoplasmic reticulum
0.38	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0031090	organelle membrane
0.36	GO:0005829	cytosol
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0005769	early endosome
0.35	GO:0005634	nucleus
0.35	GO:0098805	whole membrane
0.35	GO:0043232	intracellular non-membrane-bounded organelle

0.57

GO:0004745

sp|P50229|CCL3_RAT
C-C motif chemokine 3
Search

0.75	C-C motif chemokine

0.80	GO:0060326	cell chemotaxis
0.73	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.59	GO:0097529	myeloid leukocyte migration
0.58	GO:0071674	mononuclear cell migration
0.57	GO:0072676	lymphocyte migration
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.56	GO:0043615	astrocyte cell migration
0.54	GO:0006954	inflammatory response
0.54	GO:0071347	cellular response to interleukin-1

0.82	GO:0008009	chemokine activity
0.56	GO:0048020	CCR chemokine receptor binding
0.53	GO:0004698	calcium-dependent protein kinase C activity
0.51	GO:0016004	phospholipase activator activity
0.50	GO:0042056	chemoattractant activity
0.41	GO:0042802	identical protein binding
0.35	GO:0008201	heparin binding
0.33	GO:0003735	structural constituent of ribosome

0.70	GO:0005615	extracellular space
0.43	GO:0005829	cytosol
0.34	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0015934	large ribosomal subunit
0.30	GO:0044425	membrane part

0.53

GO:0004698

sp|P50230|CCL4_RAT
C-C motif chemokine 4
Search

CCL4

0.74	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.71	GO:0010469	regulation of receptor activity
0.55	GO:0070098	chemokine-mediated signaling pathway
0.54	GO:0006954	inflammatory response
0.52	GO:0071674	mononuclear cell migration
0.52	GO:1990266	neutrophil migration
0.51	GO:0072676	lymphocyte migration
0.51	GO:0071347	cellular response to interleukin-1
0.50	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0008009	chemokine activity
0.58	GO:0048020	CCR chemokine receptor binding
0.39	GO:0004698	calcium-dependent protein kinase C activity
0.39	GO:0042802	identical protein binding
0.39	GO:0016004	phospholipase activator activity
0.38	GO:0042056	chemoattractant activity
0.34	GO:0008201	heparin binding
0.33	GO:0003735	structural constituent of ribosome

0.70	GO:0005615	extracellular space
0.36	GO:0005829	cytosol
0.33	GO:0015934	large ribosomal subunit
0.30	GO:0016020	membrane

0.39

GO:0004698

sp|P50231|CCL5_RAT
C-C motif chemokine 5
Search

CCL5

0.76	C-C motif chemokine

0.82	GO:0070098	chemokine-mediated signaling pathway
0.82	GO:0060326	cell chemotaxis
0.79	GO:0006954	inflammatory response
0.75	GO:0009615	response to virus
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.63	GO:0010820	positive regulation of T cell chemotaxis
0.62	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin
0.62	GO:2000503	positive regulation of natural killer cell chemotaxis
0.62	GO:0031584	activation of phospholipase D activity

0.86	GO:0031729	CCR4 chemokine receptor binding
0.86	GO:0031726	CCR1 chemokine receptor binding
0.86	GO:0031730	CCR5 chemokine receptor binding
0.84	GO:0008009	chemokine activity
0.63	GO:0046817	chemokine receptor antagonist activity
0.61	GO:0016004	phospholipase activator activity
0.61	GO:0030298	receptor signaling protein tyrosine kinase activator activity
0.60	GO:0042056	chemoattractant activity
0.58	GO:0043621	protein self-association
0.56	GO:0004435	phosphatidylinositol phospholipase C activity

0.73	GO:0005615	extracellular space
0.39	GO:0005737	cytoplasm

0.56	EC:3.1.4.11	GO:0004435
0.56	KEGG:R03435	GO:0004435

sp|P50232|SYT4_RAT
Synaptotagmin-4
Search

SYT4

0.96	Synaptotagmin IV

0.74	GO:0006887	exocytosis
0.60	GO:0033604	negative regulation of catecholamine secretion
0.58	GO:1903861	positive regulation of dendrite extension
0.52	GO:1905433	negative regulation of retrograde trans-synaptic signaling by neuropeptide
0.52	GO:0048174	negative regulation of short-term neuronal synaptic plasticity
0.52	GO:0017158	regulation of calcium ion-dependent exocytosis
0.51	GO:0007269	neurotransmitter secretion
0.51	GO:0014049	positive regulation of glutamate secretion
0.50	GO:0050709	negative regulation of protein secretion
0.50	GO:0014059	regulation of dopamine secretion

0.51	GO:0005544	calcium-dependent phospholipid binding
0.48	GO:0000149	SNARE binding
0.46	GO:0030276	clathrin binding
0.46	GO:0005509	calcium ion binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0001786	phosphatidylserine binding
0.39	GO:0048487	beta-tubulin binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0031369	translation initiation factor binding
0.37	GO:0046982	protein heterodimerization activity

0.51	GO:1990742	microvesicle
0.51	GO:0097449	astrocyte projection
0.50	GO:0031045	dense core granule
0.50	GO:0098793	presynapse
0.48	GO:0043005	neuron projection
0.47	GO:0043025	neuronal cell body
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0120038	plasma membrane bounded cell projection part
0.44	GO:0005794	Golgi apparatus
0.43	GO:0005886	plasma membrane

sp|P50233|DHI2_RAT
Corticosteroid 11-beta-dehydrogenase isozyme 2
Search

HSD11B2

0.97	Corticosteroid 11-beta-dehydrogenase isozyme 2

0.55	GO:0007565	female pregnancy
0.51	GO:0055114	oxidation-reduction process
0.43	GO:0008211	glucocorticoid metabolic process
0.42	GO:0002017	regulation of blood volume by renal aldosterone
0.40	GO:0032094	response to food
0.40	GO:0051384	response to glucocorticoid
0.39	GO:0032868	response to insulin
0.39	GO:0001666	response to hypoxia
0.37	GO:0042493	response to drug
0.36	GO:0033555	multicellular organismal response to stress

0.52	GO:0016491	oxidoreductase activity
0.39	GO:0005496	steroid binding
0.37	GO:0051287	NAD binding
0.32	GO:0016829	lyase activity
0.32	GO:0016301	kinase activity

0.40	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016491

sp|P50235|SUH3_RAT
Alcohol sulfotransferase
Search

0.53	Alcohol sulfotransferase A

0.53	GO:0051923	sulfation
0.53	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.50	GO:0008202	steroid metabolic process
0.49	GO:0006068	ethanol catabolic process
0.46	GO:0042403	thyroid hormone metabolic process
0.43	GO:0006805	xenobiotic metabolic process
0.42	GO:0045606	positive regulation of epidermal cell differentiation
0.40	GO:0071305	cellular response to vitamin D
0.40	GO:0017085	response to insecticide
0.40	GO:0008285	negative regulation of cell proliferation

0.78	GO:0008146	sulfotransferase activity
0.43	GO:1990239	steroid hormone binding
0.41	GO:0015485	cholesterol binding
0.41	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.35	GO:0003676	nucleic acid binding
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.46	GO:0005829	cytosol
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0043230	extracellular organelle
0.35	GO:0043229	intracellular organelle
0.35	GO:0005615	extracellular space
0.34	GO:0012505	endomembrane system
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0008146

sp|P50237|ST1C1_RAT
Sulfotransferase 1C1
Search

SULT1C3

0.57	Sulfotransferase

0.50	GO:0051923	sulfation
0.48	GO:0006068	ethanol catabolic process
0.47	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.39	GO:0042403	thyroid hormone metabolic process
0.38	GO:0006805	xenobiotic metabolic process
0.34	GO:0009812	flavonoid metabolic process
0.34	GO:0030855	epithelial cell differentiation

0.78

GO:0008146

sulfotransferase activity

0.41	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.34	GO:0005764	lysosome

0.78

GO:0008146

sp|P50279|STX2_RAT
Syntaxin-2
Search

STX2

0.97	Epimorphin

0.82	GO:0007340	acrosome reaction
0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0030154	cell differentiation
0.67	GO:0006886	intracellular protein transport
0.66	GO:0061025	membrane fusion
0.55	GO:1903575	cornified envelope assembly
0.54	GO:0033194	response to hydroperoxide
0.53	GO:0097480	establishment of synaptic vesicle localization
0.53	GO:0099504	synaptic vesicle cycle
0.53	GO:0007269	neurotransmitter secretion

0.78	GO:0005484	SNAP receptor activity
0.49	GO:0000149	SNARE binding
0.45	GO:0046983	protein dimerization activity
0.43	GO:0019901	protein kinase binding
0.42	GO:0005102	receptor binding
0.38	GO:0048306	calcium-dependent protein binding
0.36	GO:0019904	protein domain specific binding

0.52	GO:0098793	presynapse
0.51	GO:0030027	lamellipodium
0.51	GO:0016323	basolateral plasma membrane
0.50	GO:0031201	SNARE complex
0.49	GO:0070382	exocytic vesicle
0.47	GO:0005615	extracellular space
0.44	GO:0030424	axon
0.37	GO:0005652	nuclear lamina
0.37	GO:0097060	synaptic membrane
0.37	GO:0005911	cell-cell junction

sp|P50280|MMP7_RAT
Matrilysin
Search

MMP7

0.64	Macrophage metalloelastase

0.61	GO:0006508	proteolysis
0.46	GO:0030574	collagen catabolic process
0.44	GO:0009653	anatomical structure morphogenesis
0.44	GO:0009888	tissue development
0.44	GO:0042060	wound healing
0.44	GO:0042127	regulation of cell proliferation
0.43	GO:0045089	positive regulation of innate immune response
0.43	GO:0030154	cell differentiation
0.42	GO:0072359	circulatory system development
0.42	GO:0009605	response to external stimulus

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.40	GO:0005518	collagen binding
0.39	GO:0001047	core promoter binding
0.38	GO:0008201	heparin binding
0.38	GO:0005509	calcium ion binding
0.38	GO:0004252	serine-type endopeptidase activity
0.36	GO:0043565	sequence-specific DNA binding
0.32	GO:0016746	transferase activity, transferring acyl groups

0.74	GO:0031012	extracellular matrix
0.43	GO:0005615	extracellular space
0.40	GO:0009986	cell surface
0.38	GO:0030425	dendrite
0.37	GO:0098552	side of membrane
0.37	GO:0030017	sarcomere
0.37	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|P50282|MMP9_RAT
Matrix metalloproteinase-9
Search

0.64	Matrix metalloproteinase

0.76	GO:0030574	collagen catabolic process
0.71	GO:0050900	leukocyte migration
0.71	GO:0001503	ossification
0.61	GO:0006508	proteolysis
0.58	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.58	GO:1900122	positive regulation of receptor binding
0.58	GO:0051549	positive regulation of keratinocyte migration
0.58	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.57	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.56	GO:0007566	embryo implantation

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.50	GO:0042802	identical protein binding
0.40	GO:0001968	fibronectin binding
0.38	GO:0032403	protein complex binding
0.37	GO:0004252	serine-type endopeptidase activity

0.74	GO:0031012	extracellular matrix
0.51	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.35	GO:0030017	sarcomere
0.35	GO:0043234	protein complex
0.33	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|P50297|ARY1_RAT
Arylamine N-acetyltransferase 1
Search

NAT1

0.75	N-acetyltransferase 1

0.30

GO:0008152

metabolic process

0.67

GO:0016407

acetyltransferase activity

0.67

GO:0016407

sp|P50298|ARY2_RAT
Arylamine N-acetyltransferase 2
Search

NAT1

0.62	Arylamine N-acetyltransferase

0.39	GO:0097068	response to thyroxine
0.37	GO:0001889	liver development
0.37	GO:0007568	aging
0.37	GO:0009410	response to xenobiotic stimulus
0.36	GO:1902475	L-alpha-amino acid transmembrane transport
0.35	GO:0048565	digestive tract development
0.35	GO:0032496	response to lipopolysaccharide
0.35	GO:0001666	response to hypoxia
0.34	GO:0070887	cellular response to chemical stimulus
0.30	GO:0044237	cellular metabolic process

0.67	GO:0016407	acetyltransferase activity
0.46	GO:0016410	N-acyltransferase activity
0.36	GO:0015179	L-amino acid transmembrane transporter activity
0.33	GO:0005515	protein binding

0.37	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.67

GO:0016407

sp|P50339|CMA1_RAT
Chymase
Search

CMA1

0.96	Skeletal muscle neutral protease mekratin

0.61	GO:0006508	proteolysis
0.56	GO:0042222	interleukin-1 biosynthetic process
0.54	GO:0034769	basement membrane disassembly
0.53	GO:0032611	interleukin-1 beta production
0.48	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.48	GO:0001909	leukocyte mediated cytotoxicity
0.47	GO:0002228	natural killer cell mediated immunity
0.39	GO:0030901	midbrain development
0.39	GO:0071333	cellular response to glucose stimulus
0.39	GO:0045766	positive regulation of angiogenesis

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.34	GO:0008201	heparin binding

0.55	GO:0030141	secretory granule
0.47	GO:0031012	extracellular matrix
0.37	GO:0005615	extracellular space
0.36	GO:0044194	cytolytic granule
0.34	GO:0001772	immunological synapse
0.34	GO:0005829	cytosol
0.34	GO:0010494	cytoplasmic stress granule
0.34	GO:0005769	early endosome
0.32	GO:0005634	nucleus
0.32	GO:0005739	mitochondrion

0.69

GO:0004252

sp|P50343|TRYB2_RAT
Tryptase beta-2
Search

0.79	Mast cell tryptase beta III

0.61	GO:0006508	proteolysis
0.40	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.39	GO:0050878	regulation of body fluid levels
0.38	GO:0050817	coagulation
0.38	GO:0042060	wound healing
0.37	GO:0050819	negative regulation of coagulation
0.37	GO:0061045	negative regulation of wound healing
0.37	GO:0022617	extracellular matrix disassembly
0.35	GO:0006952	defense response
0.35	GO:0048771	tissue remodeling

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0008201	heparin binding
0.36	GO:0005515	protein binding
0.35	GO:0005509	calcium ion binding
0.33	GO:0005044	scavenger receptor activity

0.44	GO:0005576	extracellular region
0.37	GO:0042629	mast cell granule
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P50393|PA24A_RAT
Cytosolic phospholipase A2
Search

PLA2G4A

0.66	Cytosolic phospholipase A2

0.80	GO:0009395	phospholipid catabolic process
0.58	GO:0071236	cellular response to antibiotic
0.56	GO:0046456	icosanoid biosynthetic process
0.54	GO:0050482	arachidonic acid secretion
0.51	GO:0042127	regulation of cell proliferation
0.43	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.37	GO:0019369	arachidonic acid metabolic process
0.37	GO:0022602	ovulation cycle process
0.37	GO:0008585	female gonad development
0.36	GO:0036150	phosphatidylserine acyl-chain remodeling

0.82	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.82	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.79	GO:0004623	phospholipase A2 activity
0.57	GO:0005544	calcium-dependent phospholipid binding
0.53	GO:0046872	metal ion binding
0.45	GO:0004622	lysophospholipase activity
0.35	GO:0035035	histone acetyltransferase binding
0.35	GO:0008970	phosphatidylcholine 1-acylhydrolase activity

0.56	GO:0005811	lipid droplet
0.49	GO:0005829	cytosol
0.49	GO:0005794	Golgi apparatus
0.49	GO:0005783	endoplasmic reticulum
0.42	GO:0031410	cytoplasmic vesicle
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0005634	nucleus
0.33	GO:0031966	mitochondrial membrane

0.79

EC:3.1.1.4

GO:0004623

sp|P50398|GDIA_RAT
Rab GDP dissociation inhibitor alpha
Search

GDI1

0.68	Rab GDP dissociation inhibitor alpha

0.77	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.55	GO:0090315	negative regulation of protein targeting to membrane
0.43	GO:0050771	negative regulation of axonogenesis
0.39	GO:0045773	positive regulation of axon extension
0.39	GO:0051592	response to calcium ion
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0043312	neutrophil degranulation

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.76	GO:0005096	GTPase activator activity
0.39	GO:0031267	small GTPase binding
0.32	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.53	GO:0043209	myelin sheath
0.50	GO:0030496	midbody
0.49	GO:0005737	cytoplasm
0.42	GO:0012505	endomembrane system
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0043025	neuronal cell body
0.38	GO:0030424	axon
0.37	GO:0043229	intracellular organelle
0.35	GO:0043234	protein complex
0.34	GO:0005925	focal adhesion

0.32

GO:0016740

sp|P50399|GDIB_RAT
Rab GDP dissociation inhibitor beta
Search

GDI2

0.68	Rab GDP dissociation inhibitor beta

0.76	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.49	GO:0090315	negative regulation of protein targeting to membrane
0.41	GO:0050771	negative regulation of axonogenesis
0.38	GO:0045773	positive regulation of axon extension
0.37	GO:0051592	response to calcium ion
0.36	GO:0016192	vesicle-mediated transport
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0002283	neutrophil activation involved in immune response

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.76	GO:0005096	GTPase activator activity
0.39	GO:0031267	small GTPase binding
0.34	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.52	GO:0043209	myelin sheath
0.48	GO:0005737	cytoplasm
0.45	GO:0030496	midbody
0.44	GO:0012505	endomembrane system
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043229	intracellular organelle
0.37	GO:0043230	extracellular organelle
0.37	GO:0043025	neuronal cell body
0.37	GO:0030424	axon
0.36	GO:0005615	extracellular space

sp|P50408|VATF_RAT
V-type proton ATPase subunit F
Search

ATP6V1F

0.72	V-type proton ATPase subunit F

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.46	GO:1901207	regulation of heart looping
0.46	GO:0060036	notochord cell vacuolation
0.45	GO:0070121	Kupffer's vesicle development
0.44	GO:1902017	regulation of cilium assembly
0.44	GO:0060041	retina development in camera-type eye
0.42	GO:0042127	regulation of cell proliferation
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0008286	insulin receptor signaling pathway

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.35	GO:0042624	ATPase activity, uncoupled
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.81	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.47	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.37	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P50411|IPP2_RAT
Protein phosphatase inhibitor 2
Search

PPP1R2

0.88	Protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 3

0.80	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.68	GO:0009966	regulation of signal transduction
0.42	GO:0005977	glycogen metabolic process
0.36	GO:0032091	negative regulation of protein binding
0.35	GO:0006470	protein dephosphorylation

0.81	GO:0004864	protein phosphatase inhibitor activity
0.37	GO:0005515	protein binding
0.35	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0031409	pigment binding

0.50	GO:0000164	protein phosphatase type 1 complex
0.37	GO:0098723	skeletal muscle myofibril
0.36	GO:0043197	dendritic spine
0.36	GO:0030426	growth cone
0.30	GO:0016020	membrane

0.35

GO:0004721

sp|P50430|ARSB_RAT
Arylsulfatase B
Search

ARSB

0.89	Arylsulfatase B

0.59	GO:0061580	colon epithelial cell migration
0.53	GO:0010632	regulation of epithelial cell migration
0.42	GO:0010976	positive regulation of neuron projection development
0.41	GO:0051597	response to methylmercury
0.40	GO:0043627	response to estrogen
0.40	GO:0009268	response to pH
0.40	GO:0007584	response to nutrient
0.39	GO:0007417	central nervous system development
0.39	GO:0006914	autophagy
0.36	GO:0006687	glycosphingolipid metabolic process

0.74	GO:0008484	sulfuric ester hydrolase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0005515	protein binding

0.41	GO:0005764	lysosome
0.40	GO:0009986	cell surface
0.40	GO:0005791	rough endoplasmic reticulum
0.38	GO:0005794	Golgi apparatus
0.37	GO:0005576	extracellular region
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0005739	mitochondrion
0.36	GO:0031982	vesicle
0.35	GO:0005775	vacuolar lumen

0.74

EC:3.1.6

GO:0008484

sp|P50442|GATM_RAT
Glycine amidinotransferase, mitochondrial
Search

GATM

0.88	LOW QUALITY PROTEIN: glycine amidinotransferase, mitochondrial

0.65	GO:0006601	creatine biosynthetic process
0.63	GO:0014889	muscle atrophy
0.58	GO:0007611	learning or memory
0.51	GO:0007275	multicellular organism development
0.36	GO:0042246	tissue regeneration
0.35	GO:0007584	response to nutrient
0.35	GO:0043434	response to peptide hormone
0.35	GO:0046689	response to mercury ion
0.34	GO:0006979	response to oxidative stress

0.84

GO:0015067

amidinotransferase activity

0.56	GO:0005758	mitochondrial intermembrane space
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.1.4

GO:0015067

sp|P50463|CSRP3_RAT
Cysteine and glycine-rich protein 3
Search

CSRP3

0.86	Cysteine and glycine rich protein 3

0.57	GO:0060047	heart contraction
0.57	GO:0030239	myofibril assembly
0.52	GO:0035995	detection of muscle stretch
0.51	GO:0003300	cardiac muscle hypertrophy
0.50	GO:0002026	regulation of the force of heart contraction
0.49	GO:0006941	striated muscle contraction
0.49	GO:0055013	cardiac muscle cell development
0.47	GO:0006874	cellular calcium ion homeostasis
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0033365	protein localization to organelle

0.54	GO:0046872	metal ion binding
0.52	GO:0031433	telethonin binding
0.51	GO:0008307	structural constituent of muscle
0.48	GO:0042805	actinin binding
0.45	GO:0042802	identical protein binding
0.30	GO:0008134	transcription factor binding
0.30	GO:0003779	actin binding

0.50	GO:0030018	Z disc
0.37	GO:0005634	nucleus
0.35	GO:0015629	actin cytoskeleton

sp|P50475|SYAC_RAT
Alanine--tRNA ligase, cytoplasmic
Search

AARS

0.64	LOW QUALITY PROTEIN: alanine--tRNA ligase, cytoplasmic

0.78	GO:0006419	alanyl-tRNA aminoacylation
0.55	GO:0021680	cerebellar Purkinje cell layer development
0.54	GO:0050885	neuromuscular process controlling balance
0.53	GO:0043524	negative regulation of neuron apoptotic process
0.51	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.48	GO:0006400	tRNA modification
0.36	GO:0140018	regulation of cytoplasmic translational fidelity
0.33	GO:0006414	translational elongation
0.32	GO:0006413	translational initiation

0.78	GO:0004813	alanine-tRNA ligase activity
0.65	GO:0000049	tRNA binding
0.59	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0002161	aminoacyl-tRNA editing activity
0.45	GO:0016597	amino acid binding
0.34	GO:0008135	translation factor activity, RNA binding
0.33	GO:0005515	protein binding

0.49	GO:0005737	cytoplasm
0.39	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0070062	extracellular exosome
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.78

EC:6.1.1.7

GO:0004813

sp|P50480|ISL2_RAT
Insulin gene enhancer protein ISL-2
Search

ISL2

0.89	Insulin gene enhancer protein ISL-2

0.63	GO:0048665	neuron fate specification
0.62	GO:0021524	visceral motor neuron differentiation
0.59	GO:0007409	axonogenesis
0.58	GO:0097485	neuron projection guidance
0.57	GO:0045665	negative regulation of neuron differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0031016	pancreas development
0.52	GO:0048732	gland development

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.48	GO:0043425	bHLH transcription factor binding
0.47	GO:0001105	RNA polymerase II transcription coactivator activity
0.47	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0035326	enhancer binding
0.46	GO:1990841	promoter-specific chromatin binding
0.43	GO:0003690	double-stranded DNA binding
0.37	GO:0016922	ligand-dependent nuclear receptor binding
0.36	GO:0030331	estrogen receptor binding

0.61	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P50503|F10A1_RAT
Hsc70-interacting protein
Search

ST13

0.92	Testis secretory sperm-binding protein Li 233m

0.43	GO:0061084	negative regulation of protein refolding
0.41	GO:0051289	protein homotetramerization
0.40	GO:0051085	chaperone cofactor-dependent protein refolding
0.33	GO:0006351	transcription, DNA-templated

0.65	GO:0046983	protein dimerization activity
0.43	GO:0032564	dATP binding
0.41	GO:0030544	Hsp70 protein binding
0.39	GO:0051087	chaperone binding
0.39	GO:0019904	protein domain specific binding
0.39	GO:0032403	protein complex binding
0.39	GO:0042802	identical protein binding
0.38	GO:0051082	unfolded protein binding
0.35	GO:0030674	protein binding, bridging

0.45	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.36	GO:0043234	protein complex
0.33	GO:0005634	nucleus

sp|P50545|HCK_RAT
Tyrosine-protein kinase HCK
Search

HCK

0.58	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.51	GO:0046777	protein autophosphorylation
0.51	GO:0070666	regulation of mast cell proliferation
0.50	GO:0002774	Fc receptor mediated inhibitory signaling pathway
0.50	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway
0.50	GO:2000670	positive regulation of dendritic cell apoptotic process
0.49	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.49	GO:1905247	positive regulation of aspartic-type peptidase activity
0.49	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
0.49	GO:0002513	tolerance induction to self antigen

0.81	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0140031	phosphorylation-dependent protein binding
0.48	GO:0046875	ephrin receptor binding
0.47	GO:0044325	ion channel binding
0.45	GO:0017124	SH3 domain binding
0.44	GO:0032403	protein complex binding

0.48	GO:0005654	nucleoplasm
0.46	GO:0045121	membrane raft
0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0005794	Golgi apparatus
0.35	GO:0034666	integrin alpha2-beta1 complex
0.35	GO:0042629	mast cell granule
0.35	GO:0030061	mitochondrial crista
0.34	GO:0014069	postsynaptic density
0.34	GO:0005913	cell-cell adherens junction

0.81

GO:0004715

sp|P50554|GABT_RAT
4-aminobutyrate aminotransferase, mitochondrial
Search

ABAT

0.52	Mitochondrial 4-aminobutyrate aminotransferase

0.77	GO:0009448	gamma-aminobutyric acid metabolic process
0.58	GO:0048148	behavioral response to cocaine
0.42	GO:1904448	regulation of aspartate secretion
0.42	GO:0014053	negative regulation of gamma-aminobutyric acid secretion
0.42	GO:1902722	positive regulation of prolactin secretion
0.42	GO:0033602	negative regulation of dopamine secretion
0.41	GO:0070474	positive regulation of uterine smooth muscle contraction
0.41	GO:0097151	positive regulation of inhibitory postsynaptic potential
0.41	GO:0045915	positive regulation of catecholamine metabolic process
0.41	GO:0031652	positive regulation of heat generation

0.79	GO:0003867	4-aminobutyrate transaminase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.51	GO:0042803	protein homodimerization activity
0.43	GO:0047298	(S)-3-amino-2-methylpropionate transaminase activity
0.42	GO:0032145	succinate-semialdehyde dehydrogenase binding
0.37	GO:0051536	iron-sulfur cluster binding
0.35	GO:0046872	metal ion binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0005524	ATP binding

0.60	GO:0032144	4-aminobutyrate transaminase complex
0.45	GO:0005739	mitochondrion
0.38	GO:0043005	neuron projection
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0070062	extracellular exosome
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.33	GO:0043234	protein complex

0.79	EC:2.6.1.19	GO:0003867
0.43	KEGG:R04188	GO:0047298

sp|P50569|STF1_RAT
Steroidogenic factor 1
Search

NR5A1

0.92	Steroidogenic factor 1 nuclear receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:2000195	negative regulation of female gonad development
0.59	GO:2000020	positive regulation of male gonad development
0.59	GO:0030325	adrenal gland development
0.59	GO:0001553	luteinization
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0051457	maintenance of protein location in nucleus
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:0008584	male gonad development

0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0035326	enhancer binding
0.57	GO:0003682	chromatin binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0005543	phospholipid binding
0.54	GO:0003690	double-stranded DNA binding
0.49	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.56	GO:0005667	transcription factor complex
0.46	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.33	GO:0005694	chromosome
0.33	GO:1905369	endopeptidase complex

sp|P50572|GBRR1_RAT
Gamma-aminobutyric acid receptor subunit rho-1
Search

GABRR1

0.96	LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit rho-1

0.59	GO:0007165	signal transduction
0.59	GO:0034220	ion transmembrane transport
0.45	GO:0007601	visual perception
0.38	GO:0006821	chloride transport
0.34	GO:0007268	chemical synaptic transmission

0.76	GO:0004890	GABA-A receptor activity
0.74	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0005254	chloride channel activity
0.34	GO:0019904	protein domain specific binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity

0.55	GO:0005886	plasma membrane
0.52	GO:1902711	GABA-A receptor complex
0.39	GO:0034707	chloride channel complex
0.38	GO:0098794	postsynapse
0.38	GO:0030054	cell junction

sp|P50573|GBRR3_RAT
Gamma-aminobutyric acid receptor subunit rho-3
Search

GABRR3

0.96	LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit rho-3

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.41	GO:0007601	visual perception
0.37	GO:0006821	chloride transport
0.36	GO:0007268	chemical synaptic transmission
0.35	GO:0032259	methylation

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity
0.38	GO:0019904	protein domain specific binding
0.37	GO:0005254	chloride channel activity
0.35	GO:0008168	methyltransferase activity

0.55	GO:0005886	plasma membrane
0.51	GO:1902711	GABA-A receptor complex
0.38	GO:0034707	chloride channel complex
0.37	GO:0098794	postsynapse
0.37	GO:0030054	cell junction

0.35

GO:0008168

sp|P50575|DLX5_RAT
Homeobox protein DLX-5
Search

DLX5

0.97	Distal-less homeo box 5

0.64	GO:0060166	olfactory pit development
0.64	GO:0097376	interneuron axon guidance
0.62	GO:0021889	olfactory bulb interneuron differentiation
0.61	GO:0001958	endochondral ossification
0.61	GO:0060325	face morphogenesis
0.59	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
0.59	GO:0060021	palate development
0.59	GO:0001649	osteoblast differentiation
0.59	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.59	GO:0030509	BMP signaling pathway

0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0071837	HMG box domain binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0000785	chromatin
0.50	GO:0031974	membrane-enclosed lumen
0.40	GO:0005737	cytoplasm

sp|P50596|LEP_RAT
Leptin
Search

LEP

0.97

Leptin

0.76	GO:0010469	regulation of receptor activity
0.64	GO:1990051	activation of protein kinase C activity
0.64	GO:0032615	interleukin-12 production
0.64	GO:0072604	interleukin-6 secretion
0.63	GO:0032310	prostaglandin secretion
0.63	GO:0072606	interleukin-8 secretion
0.63	GO:0032817	regulation of natural killer cell proliferation
0.62	GO:0032868	response to insulin
0.62	GO:0090335	regulation of brown fat cell differentiation
0.62	GO:0032099	negative regulation of appetite

0.79	GO:0005179	hormone activity
0.49	GO:0051428	peptide hormone receptor binding
0.35	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P50609|FMOD_RAT
Fibromodulin
Search

FMOD

0.97	Fibromodulin

0.65	GO:0030199	collagen fibril organization
0.48	GO:0032501	multicellular organismal process
0.48	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.48	GO:0000904	cell morphogenesis involved in differentiation
0.47	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0032914	positive regulation of transforming growth factor beta1 production
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0042340	keratan sulfate catabolic process
0.36	GO:0070848	response to growth factor
0.36	GO:0018146	keratan sulfate biosynthetic process

0.42	GO:0005518	collagen binding
0.32	GO:0004930	G-protein coupled receptor activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.56	GO:0005615	extracellular space
0.39	GO:0044420	extracellular matrix component
0.38	GO:0005581	collagen trimer
0.37	GO:0099512	supramolecular fiber
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen
0.33	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P50617|DEND_RAT
Dendrin
Search

DDN

0.97

Dendrin

0.57

GO:0045944

positive regulation of transcription by RNA polymerase II

0.60	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.60	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0005515	protein binding

0.68	GO:0042995	cell projection
0.61	GO:0005634	nucleus
0.56	GO:0005886	plasma membrane
0.54	GO:0043204	perikaryon
0.51	GO:0031252	cell leading edge
0.50	GO:0098794	postsynapse
0.49	GO:0005737	cytoplasm
0.48	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.46	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|P50745|SH2B3_RAT
SH2B adapter protein 3
Search

0.70	SH2B adapter protein 3

0.76	GO:0009967	positive regulation of signal transduction
0.63	GO:0030097	hemopoiesis
0.61	GO:0007165	signal transduction
0.45	GO:0045589	regulation of regulatory T cell differentiation
0.45	GO:1903671	negative regulation of sprouting angiogenesis
0.44	GO:0048568	embryonic organ development
0.42	GO:0030154	cell differentiation

0.84	GO:0035591	signaling adaptor activity
0.61	GO:0004871	signal transducer activity
0.42	GO:0042301	phosphate ion binding
0.41	GO:0032403	protein complex binding

0.44	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P50753|TNNT2_RAT
Troponin T, cardiac muscle
Search

TNNT2

0.92	Cardiac troponin T

0.83	GO:0006937	regulation of muscle contraction
0.61	GO:0030049	muscle filament sliding
0.61	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.59	GO:0008016	regulation of heart contraction
0.57	GO:0051592	response to calcium ion
0.57	GO:0060047	heart contraction
0.57	GO:0006941	striated muscle contraction
0.56	GO:0032780	negative regulation of ATPase activity
0.55	GO:0032781	positive regulation of ATPase activity
0.44	GO:0045214	sarcomere organization

0.62	GO:0030172	troponin C binding
0.61	GO:0031013	troponin I binding
0.58	GO:0005523	tropomyosin binding
0.52	GO:0003779	actin binding
0.37	GO:0030674	protein binding, bridging
0.36	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0016887	ATPase activity
0.32	GO:0046872	metal ion binding

0.84	GO:0005861	troponin complex
0.57	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

GO:0016887

sp|P50878|RL4_RAT
60S ribosomal protein L4
Search

RPL4

0.71	Ribosomal protein L4

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0003360	brainstem development
0.35	GO:0045773	positive regulation of axon extension
0.35	GO:0071417	cellular response to organonitrogen compound
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0007420	brain development
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.48	GO:0005791	rough endoplasmic reticulum
0.43	GO:0044445	cytosolic part
0.41	GO:0005634	nucleus
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031672	A band
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P50904|RASA1_RAT
Ras GTPase-activating protein 1
Search

RASA1

0.95	Ras GTPase-activating protein 1

0.83	GO:0046580	negative regulation of Ras protein signal transduction
0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.57	GO:0001953	negative regulation of cell-matrix adhesion
0.57	GO:0001568	blood vessel development
0.53	GO:0043066	negative regulation of apoptotic process
0.53	GO:0030833	regulation of actin filament polymerization
0.50	GO:0009653	anatomical structure morphogenesis
0.40	GO:1901215	negative regulation of neuron death
0.40	GO:0043523	regulation of neuron apoptotic process

0.75	GO:0005096	GTPase activator activity
0.56	GO:0001784	phosphotyrosine residue binding
0.51	GO:0051020	GTPase binding
0.50	GO:0005102	receptor binding
0.36	GO:0043422	protein kinase B binding
0.36	GO:0019870	potassium channel inhibitor activity
0.35	GO:1990782	protein tyrosine kinase binding
0.35	GO:0044325	ion channel binding
0.34	GO:0032403	protein complex binding
0.34	GO:0008134	transcription factor binding

0.54	GO:0001726	ruffle
0.48	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0031965	nuclear membrane

sp|P51111|HD_RAT
Huntingtin
Search

HTT

0.91	Huntingtin

0.63	GO:1905335	regulation of aggrephagy
0.62	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.61	GO:0098596	imitative learning
0.61	GO:1904504	positive regulation of lipophagy
0.60	GO:0098598	learned vocalization behavior or vocal learning
0.60	GO:0031223	auditory behavior
0.59	GO:1903599	positive regulation of autophagy of mitochondrion
0.59	GO:0045724	positive regulation of cilium assembly
0.58	GO:0031648	protein destabilization
0.57	GO:0047496	vesicle transport along microtubule

0.60	GO:0034452	dynactin binding
0.60	GO:0005522	profilin binding
0.58	GO:0045505	dynein intermediate chain binding
0.57	GO:0002039	p53 binding
0.57	GO:0044325	ion channel binding
0.57	GO:0048487	beta-tubulin binding
0.54	GO:0019900	kinase binding
0.53	GO:0031072	heat shock protein binding
0.52	GO:0042802	identical protein binding
0.45	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.57	GO:0016234	inclusion body
0.57	GO:0005776	autophagosome
0.56	GO:0005814	centriole
0.55	GO:0030425	dendrite
0.55	GO:0005770	late endosome
0.55	GO:0030424	axon
0.54	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0030659	cytoplasmic vesicle membrane
0.50	GO:0005794	Golgi apparatus

sp|P51145|FOSL2_RAT
Fos-related antigen 2
Search

FOSL2

0.97	FOS like 2, AP-1 transcription factor subunit

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0003334	keratinocyte development
0.57	GO:0048146	positive regulation of fibroblast proliferation
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0035994	response to muscle stretch
0.46	GO:0045672	positive regulation of osteoclast differentiation
0.46	GO:0071277	cellular response to calcium ion
0.46	GO:0035914	skeletal muscle cell differentiation
0.46	GO:0071276	cellular response to cadmium ion

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0003682	chromatin binding
0.46	GO:0070412	R-SMAD binding
0.45	GO:0001102	RNA polymerase II activating transcription factor binding
0.45	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.45	GO:0001046	core promoter sequence-specific DNA binding
0.44	GO:0000987	proximal promoter sequence-specific DNA binding
0.42	GO:0046982	protein heterodimerization activity

0.52	GO:0005654	nucleoplasm
0.47	GO:0005667	transcription factor complex
0.42	GO:0032993	protein-DNA complex
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005829	cytosol
0.35	GO:0070552	BRISC complex
0.35	GO:0070531	BRCA1-A complex
0.35	GO:0043005	neuron projection
0.33	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P51146|RAB4B_RAT
Ras-related protein Rab-4B
Search

RAB4B

0.76	Ras-related protein Rab-4B

0.48	GO:0030100	regulation of endocytosis
0.39	GO:0046323	glucose import
0.39	GO:0015031	protein transport
0.37	GO:0002376	immune system process
0.36	GO:0032482	Rab protein signal transduction
0.35	GO:0045055	regulated exocytosis
0.35	GO:0001775	cell activation
0.35	GO:0032781	positive regulation of ATPase activity

0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0032561	guanyl ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0008565	protein transporter activity
0.35	GO:0051117	ATPase binding
0.35	GO:0019905	syntaxin binding
0.35	GO:0001671	ATPase activator activity

0.51	GO:0032593	insulin-responsive compartment
0.46	GO:0005768	endosome
0.42	GO:0005739	mitochondrion
0.40	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0044433	cytoplasmic vesicle part
0.37	GO:0098805	whole membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0012506	vesicle membrane
0.36	GO:0005886	plasma membrane

sp|P51156|RAB26_RAT
Ras-related protein Rab-26
Search

RAB26

0.89	Putative rab subfamily protein of small gtpase

0.56	GO:0043001	Golgi to plasma membrane protein transport
0.56	GO:0035272	exocrine system development
0.55	GO:0045055	regulated exocytosis
0.46	GO:0017157	regulation of exocytosis
0.45	GO:0006904	vesicle docking involved in exocytosis
0.42	GO:0009306	protein secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity

0.56	GO:0030667	secretory granule membrane
0.51	GO:0000139	Golgi membrane
0.45	GO:0008021	synaptic vesicle
0.43	GO:0005768	endosome
0.38	GO:0005886	plasma membrane
0.38	GO:0030658	transport vesicle membrane
0.30	GO:0044425	membrane part

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P51158|RAB28_RAT
Ras-related protein Rab-28
Search

RAB28

0.97	LOW QUALITY PROTEIN: ras-related protein Rab-28-like

0.48

GO:1901998

toxin transport

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0035253	ciliary rootlet
0.41	GO:0036064	ciliary basal body
0.35	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P51179|NR4A3_RAT
Nuclear receptor subfamily 4 group A member 3
Search

NR4A3

0.95	Neuron-derived orphan receptor-1 alfa

0.80	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.66	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.61	GO:0045444	fat cell differentiation
0.61	GO:0043524	negative regulation of neuron apoptotic process
0.61	GO:0038097	positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway
0.61	GO:0009444	pyruvate oxidation
0.60	GO:0032765	positive regulation of mast cell cytokine production
0.60	GO:0030534	adult behavior
0.60	GO:0030900	forebrain development

0.82	GO:0004879	nuclear receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.60	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0001223	transcription coactivator binding
0.57	GO:0035035	histone acetyltransferase binding
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0001047	core promoter binding
0.54	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.57	GO:0042629	mast cell granule
0.51	GO:0005667	transcription factor complex
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part

sp|P51400|RED1_RAT
Double-stranded RNA-specific editase 1
Search

ADARB1

0.82	Double-stranded RNA-specific editase 1

0.63	GO:0006396	RNA processing
0.48	GO:0021618	hypoglossal nerve morphogenesis
0.48	GO:0097049	motor neuron apoptotic process
0.48	GO:0021965	spinal cord ventral commissure morphogenesis
0.47	GO:0061744	motor behavior
0.47	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.47	GO:0021610	facial nerve morphogenesis
0.47	GO:0050884	neuromuscular process controlling posture
0.46	GO:0060384	innervation
0.46	GO:0045070	positive regulation of viral genome replication

0.79	GO:0004000	adenosine deaminase activity
0.59	GO:0003723	RNA binding
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0046872	metal ion binding

0.42	GO:0005730	nucleolus
0.41	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol

0.79

EC:3.5.4.4

GO:0004000

sp|P51433|PA2G5_RAT
Calcium-dependent phospholipase A2
Search

PLA2G5

0.63	Acidic phospholipase A2 daboiatoxin A chain

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.52	GO:0010518	positive regulation of phospholipase activity
0.51	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.49	GO:0009405	pathogenesis
0.39	GO:0019370	leukotriene biosynthetic process
0.39	GO:0051591	response to cAMP
0.38	GO:0034374	low-density lipoprotein particle remodeling
0.38	GO:0043030	regulation of macrophage activation

0.82	GO:0004623	phospholipase A2 activity
0.72	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.72	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.70	GO:0005509	calcium ion binding
0.51	GO:0090729	toxin activity
0.38	GO:0008201	heparin binding
0.37	GO:0019834	phospholipase A2 inhibitor activity
0.36	GO:0005102	receptor binding

0.66	GO:0005576	extracellular region
0.40	GO:0072556	other organism presynaptic membrane
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005794	Golgi apparatus
0.36	GO:0009986	cell surface
0.35	GO:0035792	other organism postsynaptic membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:3.1.1.4

GO:0004623

sp|P51489|OPSD_RAT
Rhodopsin
Search

RHO

0.57

Rhodopsin

0.79	GO:0007602	phototransduction
0.75	GO:0007601	visual perception
0.71	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0016037	light absorption
0.59	GO:0071482	cellular response to light stimulus
0.56	GO:0045494	photoreceptor cell maintenance
0.55	GO:0060041	retina development in camera-type eye
0.51	GO:0009584	detection of visible light
0.45	GO:0006468	protein phosphorylation

0.75	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.53	GO:0005502	11-cis retinal binding
0.40	GO:0042802	identical protein binding
0.39	GO:0046872	metal ion binding
0.38	GO:0046983	protein dimerization activity
0.37	GO:0030507	spectrin binding
0.36	GO:0002046	opsin binding
0.35	GO:1990763	arrestin family protein binding
0.35	GO:0001965	G-protein alpha-subunit binding

0.66	GO:0060342	photoreceptor inner segment membrane
0.65	GO:0097381	photoreceptor disc membrane
0.64	GO:0042622	photoreceptor outer segment membrane
0.52	GO:0005911	cell-cell junction
0.50	GO:0005794	Golgi apparatus
0.36	GO:0031984	organelle subcompartment
0.35	GO:0097648	G-protein coupled receptor complex
0.35	GO:0005791	rough endoplasmic reticulum
0.34	GO:0030660	Golgi-associated vesicle membrane
0.34	GO:0000786	nucleosome

sp|P51514|HTF4_RAT
Transcription factor 12
Search

TCF12

0.93	Transcription factor 4 isoform C

0.57	GO:0045666	positive regulation of neuron differentiation
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0006366	transcription by RNA polymerase II
0.32	GO:1902036	regulation of hematopoietic stem cell differentiation
0.32	GO:0007517	muscle organ development
0.32	GO:0006955	immune response

0.67	GO:0046983	protein dimerization activity
0.60	GO:0043425	bHLH transcription factor binding
0.60	GO:0070888	E-box binding
0.57	GO:0046332	SMAD binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0042802	identical protein binding
0.42	GO:0071837	HMG box domain binding
0.41	GO:0035497	cAMP response element binding
0.32	GO:0035326	enhancer binding

0.55	GO:0016607	nuclear speck
0.53	GO:0005667	transcription factor complex
0.52	GO:0000790	nuclear chromatin
0.39	GO:0005737	cytoplasm

sp|P51538|CP3A9_RAT
Cytochrome P450 3A9
Search

0.96	Cytochrome P450 family 3 subfamily A polypeptide 4

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0002933	lipid hydroxylation
0.48	GO:0009822	alkaloid catabolic process
0.48	GO:0008202	steroid metabolic process
0.45	GO:0070988	demethylation
0.43	GO:0042445	hormone metabolic process
0.42	GO:0016098	monoterpenoid metabolic process
0.41	GO:0042738	exogenous drug catabolic process
0.41	GO:0042362	fat-soluble vitamin biosynthetic process
0.41	GO:1901615	organic hydroxy compound metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.53	GO:0008395	steroid hydroxylase activity
0.42	GO:0030343	vitamin D3 25-hydroxylase activity
0.42	GO:0034875	caffeine oxidase activity
0.42	GO:0070576	vitamin D 24-hydroxylase activity
0.40	GO:0005496	steroid binding
0.38	GO:0019899	enzyme binding
0.37	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P51556|DGKA_RAT
Diacylglycerol kinase alpha
Search

DGKA

0.48	Diacylglycerol kinase alpha

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.56	GO:0046339	diacylglycerol metabolic process
0.52	GO:0006654	phosphatidic acid biosynthetic process
0.50	GO:0030258	lipid modification
0.36	GO:0032501	multicellular organismal process
0.35	GO:0007599	hemostasis
0.35	GO:0042060	wound healing
0.35	GO:0001775	cell activation

0.80	GO:0004143	diacylglycerol kinase activity
0.75	GO:0003951	NAD+ kinase activity
0.69	GO:0005509	calcium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0005543	phospholipid binding

0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane

0.80	EC:2.7.1.107	GO:0004143
0.75	KEGG:R00104	GO:0003951

sp|P51574|S15A1_RAT
Solute carrier family 15 member 1
Search

SLC15A1

0.55	Proton-dependent gastrointestinal peptide transporter

0.78	GO:0006857	oligopeptide transport
0.55	GO:0055085	transmembrane transport
0.41	GO:0015804	neutral amino acid transport
0.37	GO:0015031	protein transport
0.36	GO:0051956	negative regulation of amino acid transport
0.35	GO:0007586	digestion
0.34	GO:0065009	regulation of molecular function
0.34	GO:0042121	alginic acid biosynthetic process
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0015992	proton transport

0.70	GO:0035673	oligopeptide transmembrane transporter activity
0.49	GO:0015291	secondary active transmembrane transporter activity
0.41	GO:0015175	neutral amino acid transmembrane transporter activity
0.35	GO:0016248	channel inhibitor activity
0.33	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.56	GO:0005903	brush border
0.34	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

sp|P51577|P2RX4_RAT
P2X purinoceptor 4
Search

P2RX4

0.92	Purinergic receptor P2X 4

0.85	GO:0033198	response to ATP
0.84	GO:0035590	purinergic nucleotide receptor signaling pathway
0.79	GO:0060079	excitatory postsynaptic potential
0.61	GO:0098655	cation transmembrane transport
0.58	GO:0055119	relaxation of cardiac muscle
0.58	GO:2001028	positive regulation of endothelial cell chemotaxis
0.58	GO:0010614	negative regulation of cardiac muscle hypertrophy
0.57	GO:0034405	response to fluid shear stress
0.57	GO:0051924	regulation of calcium ion transport
0.57	GO:0006937	regulation of muscle contraction

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.84	GO:0001614	purinergic nucleotide receptor activity
0.55	GO:0099604	ligand-gated calcium channel activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0045296	cadherin binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.37	GO:0042802	identical protein binding
0.37	GO:0005102	receptor binding

0.77	GO:0098794	postsynapse
0.66	GO:0005887	integral component of plasma membrane
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0030054	cell junction
0.50	GO:0005639	integral component of nuclear inner membrane
0.43	GO:0009897	external side of plasma membrane
0.42	GO:0097060	synaptic membrane
0.40	GO:0097458	neuron part
0.39	GO:0120025	plasma membrane bounded cell projection
0.39	GO:0044297	cell body

sp|P51578|P2RX5_RAT
P2X purinoceptor 5
Search

sp|P51579|P2RX6_RAT
P2X purinoceptor 6
Search

P2RX6

0.87	Purinergic receptor P2X 6

0.85	GO:0033198	response to ATP
0.85	GO:0035590	purinergic nucleotide receptor signaling pathway
0.80	GO:0060079	excitatory postsynaptic potential
0.69	GO:0051260	protein homooligomerization
0.61	GO:0098655	cation transmembrane transport

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.85	GO:0016502	nucleotide receptor activity
0.84	GO:0035586	purinergic receptor activity
0.66	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0098794	postsynapse
0.67	GO:0005887	integral component of plasma membrane
0.66	GO:0030054	cell junction
0.47	GO:0005737	cytoplasm

sp|P51583|PUR6_RAT
Multifunctional protein ADE2
Search

PAICS

0.70	Phosphoribosylaminoimidazole carboxylase/ phosphoribosylaminoimidazole succinocarboxamide synthetase

0.71	GO:0006189	'de novo' IMP biosynthetic process
0.39	GO:0043473	pigmentation
0.39	GO:0060041	retina development in camera-type eye
0.39	GO:0043009	chordate embryonic development
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0009113	purine nucleobase biosynthetic process

0.79	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
0.48	GO:0045296	cadherin binding
0.45	GO:0042802	identical protein binding
0.39	GO:0004638	phosphoribosylaminoimidazole carboxylase activity
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.79	EC:6.3.2.6	GO:0004639
0.79	KEGG:R04591	GO:0004639

sp|P51590|CP2J3_RAT
Cytochrome P450 2J3
Search

CYP2J2

0.94	Cytochrome P450 family 2 subfamily J member 2

0.53	GO:0043651	linoleic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0019373	epoxygenase P450 pathway
0.41	GO:0032966	negative regulation of collagen biosynthetic process
0.41	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway
0.40	GO:1903532	positive regulation of secretion by cell
0.40	GO:1904467	regulation of tumor necrosis factor secretion
0.40	GO:0032760	positive regulation of tumor necrosis factor production
0.39	GO:0007565	female pregnancy
0.39	GO:0001523	retinoid metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.55	GO:0008404	arachidonic acid 14,15-epoxygenase activity
0.55	GO:0008405	arachidonic acid 11,12-epoxygenase activity
0.54	GO:0071614	linoleic acid epoxygenase activity
0.39	GO:0003958	NADPH-hemoprotein reductase activity
0.34	GO:0008395	steroid hydroxylase activity
0.33	GO:0051015	actin filament binding
0.33	GO:0005200	structural constituent of cytoskeleton

0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0070062	extracellular exosome
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0031090	organelle membrane
0.33	GO:0001726	ruffle
0.33	GO:0005925	focal adhesion
0.33	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.79

GO:0016712

sp|P51593|HUWE1_RAT
E3 ubiquitin-protein ligase HUWE1 (Fragment)
Search

HUWE1

0.73	HECT, UBA and WWE domain containing 1

0.73	GO:0016567	protein ubiquitination
0.48	GO:1903955	positive regulation of protein targeting to mitochondrion
0.45	GO:0016570	histone modification
0.44	GO:0006284	base-excision repair
0.42	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0030154	cell differentiation
0.35	GO:0043312	neutrophil degranulation
0.32	GO:0006355	regulation of transcription, DNA-templated

0.74	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0016874	ligase activity
0.51	GO:0008270	zinc ion binding
0.43	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0005515	protein binding
0.34	GO:0003677	DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

sp|P51607|RENBP_RAT
N-acylglucosamine 2-epimerase
Search

RENBP

0.60	N-acylglucosamine 2-epimerase

0.54	GO:0006044	N-acetylglucosamine metabolic process
0.46	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0019262	N-acetylneuraminate catabolic process
0.39	GO:0006050	mannosamine metabolic process
0.35	GO:0008217	regulation of blood pressure
0.35	GO:0006048	UDP-N-acetylglucosamine biosynthetic process
0.33	GO:0033198	response to ATP
0.33	GO:0006468	protein phosphorylation
0.33	GO:0035590	purinergic nucleotide receptor signaling pathway
0.33	GO:0060079	excitatory postsynaptic potential

0.63	GO:0050121	N-acylglucosamine 2-epimerase activity
0.46	GO:0004866	endopeptidase inhibitor activity
0.38	GO:0042803	protein homodimerization activity
0.36	GO:0008080	N-acetyltransferase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004931	extracellularly ATP-gated cation channel activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0016502	nucleotide receptor activity

0.37	GO:0070062	extracellular exosome
0.37	GO:0071339	MLL1 complex
0.37	GO:0048188	Set1C/COMPASS complex
0.34	GO:0005829	cytosol
0.33	GO:0098794	postsynapse
0.32	GO:0005887	integral component of plasma membrane

0.63

EC:5.1.3.8

GO:0050121

sp|P51635|AK1A1_RAT
Alcohol dehydrogenase [NADP(+)]
Search

AKR1A1

0.39	Alcohol dehydrogenase

0.59	GO:0042840	D-glucuronate catabolic process
0.57	GO:0019853	L-ascorbic acid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0046185	aldehyde catabolic process
0.36	GO:0019640	glucuronate catabolic process to xylulose 5-phosphate
0.36	GO:1901685	glutathione derivative metabolic process
0.35	GO:0006335	DNA replication-dependent nucleosome assembly
0.34	GO:0006336	DNA replication-independent nucleosome assembly
0.34	GO:0006006	glucose metabolic process
0.33	GO:0044272	sulfur compound biosynthetic process

0.60	GO:0047939	L-glucuronate reductase activity
0.58	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.34	GO:0042393	histone binding
0.33	GO:0009055	electron transfer activity

0.53	GO:0016324	apical plasma membrane
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0000790	nuclear chromatin
0.33	GO:0005654	nucleoplasm
0.33	GO:0043234	protein complex

0.60	EC:1.1.1.19	GO:0047939
0.60	KEGG:R01481	GO:0047939

sp|P51638|CAV3_RAT
Caveolin-3
Search

CAV3

0.85

Caveolin

0.85	GO:0070836	caveola assembly
0.76	GO:0046716	muscle cell cellular homeostasis
0.67	GO:0023051	regulation of signaling
0.65	GO:0031623	receptor internalization
0.65	GO:0051001	negative regulation of nitric-oxide synthase activity
0.64	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus
0.63	GO:0098901	regulation of cardiac muscle cell action potential
0.62	GO:0060306	regulation of membrane repolarization
0.62	GO:0086004	regulation of cardiac muscle cell contraction
0.61	GO:0042632	cholesterol homeostasis

0.78	GO:0044325	ion channel binding
0.75	GO:0032947	protein complex scaffold activity
0.60	GO:0099106	ion channel regulator activity
0.57	GO:0071253	connexin binding
0.55	GO:0043014	alpha-tubulin binding
0.55	GO:0050998	nitric-oxide synthase binding
0.54	GO:0017080	sodium channel regulator activity
0.53	GO:0008022	protein C-terminus binding
0.51	GO:0016248	channel inhibitor activity
0.51	GO:0048365	Rac GTPase binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.57	GO:0042383	sarcolemma
0.53	GO:0016010	dystrophin-associated glycoprotein complex
0.53	GO:0005783	endoplasmic reticulum
0.51	GO:0002080	acrosomal membrane
0.50	GO:0005768	endosome
0.49	GO:0005925	focal adhesion
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005929	cilium

sp|P51639|HMDH_RAT
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Search

HMGCR

0.56	3-hydroxy-3-methylglutaryl-coenzyme A reductase

0.74	GO:0015936	coenzyme A metabolic process
0.71	GO:0008299	isoprenoid biosynthetic process
0.58	GO:0006695	cholesterol biosynthetic process
0.56	GO:0008542	visual learning
0.54	GO:0043407	negative regulation of MAP kinase activity
0.53	GO:0051262	protein tetramerization
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0061061	muscle structure development
0.40	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.40	GO:0010666	positive regulation of cardiac muscle cell apoptotic process

0.82	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity
0.70	GO:0050661	NADP binding
0.56	GO:0042282	hydroxymethylglutaryl-CoA reductase activity
0.41	GO:0043168	anion binding
0.40	GO:0051721	protein phosphatase 2A binding
0.38	GO:0042803	protein homodimerization activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.55	GO:0031903	microbody membrane
0.54	GO:0044439	peroxisomal part
0.30	GO:0016021	integral component of membrane

0.82	EC:1.1.1.34	GO:0004420
0.82	KEGG:R02082	GO:0004420

sp|P51646|ARL5A_RAT
ADP-ribosylation factor-like protein 5A
Search

ARL5A

0.97	ADP ribosylation factor like GTPase 5A

0.56	GO:1903292	protein localization to Golgi membrane
0.34	GO:0070588	calcium ion transmembrane transport

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003779	actin binding
0.35	GO:0005245	voltage-gated calcium channel activity

0.45	GO:0005622	intracellular
0.35	GO:0005891	voltage-gated calcium channel complex

sp|P51647|AL1A1_RAT
Retinal dehydrogenase 1
Search

ALDH1A1

0.81	Retinal dehydrogenase 1

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0042572	retinol metabolic process
0.44	GO:0042904	9-cis-retinoic acid biosynthetic process
0.43	GO:0002072	optic cup morphogenesis involved in camera-type eye development
0.41	GO:0043065	positive regulation of apoptotic process
0.39	GO:0042493	response to drug
0.38	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
0.38	GO:0044849	estrous cycle
0.38	GO:0007494	midgut development
0.37	GO:0032355	response to estradiol

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.41	GO:0051287	NAD binding
0.38	GO:0005497	androgen binding
0.36	GO:0042802	identical protein binding
0.36	GO:0005096	GTPase activator activity

0.47	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.69

EC:1.2.1

GO:0016620

sp|P51650|SSDH_RAT
Succinate-semialdehyde dehydrogenase, mitochondrial
Search

ALDH5A1

0.47	Succinate-semialdehyde dehydrogenase

0.77	GO:0009450	gamma-aminobutyric acid catabolic process
0.56	GO:0051289	protein homotetramerization
0.56	GO:0006681	galactosylceramide metabolic process
0.56	GO:0006678	glucosylceramide metabolic process
0.54	GO:0006105	succinate metabolic process
0.53	GO:0007417	central nervous system development
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0046459	short-chain fatty acid metabolic process
0.52	GO:0009791	post-embryonic development
0.52	GO:0006083	acetate metabolic process

0.77	GO:0009013	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
0.60	GO:0004777	succinate-semialdehyde dehydrogenase (NAD+) activity
0.42	GO:0051287	NAD binding
0.39	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.34	GO:0047949	glutarate-semialdehyde dehydrogenase activity
0.34	GO:0031406	carboxylic acid binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0005388	calcium-transporting ATPase activity
0.32	GO:0005524	ATP binding

0.46	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:1.2.1.16

GO:0009013

sp|P51651|GPR6_RAT
G-protein coupled receptor 6
Search

GPR6

0.65	G-protein coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0090520	sphingolipid mediated signaling pathway
0.54	GO:0006874	cellular calcium ion homeostasis
0.48	GO:0040020	regulation of meiotic nuclear division
0.35	GO:0019933	cAMP-mediated signaling
0.35	GO:1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation
0.34	GO:0030816	positive regulation of cAMP metabolic process
0.34	GO:0008285	negative regulation of cell proliferation

0.72	GO:0004930	G-protein coupled receptor activity
0.43	GO:0031210	phosphatidylcholine binding
0.33	GO:0005515	protein binding

0.35	GO:0005886	plasma membrane
0.34	GO:0031965	nuclear membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P51652|AKC1H_RAT
Aldo-keto reductase family 1 member C18
Search

0.95	3-hydroxyhexobarbital dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0044597	daunorubicin metabolic process
0.50	GO:0071395	cellular response to jasmonic acid stimulus
0.49	GO:0044598	doxorubicin metabolic process
0.48	GO:0008202	steroid metabolic process
0.46	GO:0071799	cellular response to prostaglandin D stimulus
0.46	GO:1900053	negative regulation of retinoic acid biosynthetic process
0.45	GO:0016488	farnesol catabolic process
0.45	GO:2000224	regulation of testosterone biosynthetic process
0.45	GO:0042574	retinal metabolic process

0.54	GO:0016491	oxidoreductase activity
0.42	GO:0032052	bile acid binding
0.36	GO:0005496	steroid binding
0.35	GO:0070401	NADP+ binding
0.35	GO:0070402	NADPH binding
0.35	GO:0015125	bile acid transmembrane transporter activity
0.33	GO:0005515	protein binding

0.40	GO:0070062	extracellular exosome
0.39	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.54

GO:0016491

sp|P51653|GPC2_RAT
Glypican-2
Search

0.91	Glypican 6, like

0.70	GO:0009966	regulation of signal transduction
0.43	GO:0016477	cell migration
0.39	GO:0007224	smoothened signaling pathway
0.38	GO:0030182	neuron differentiation
0.38	GO:0001523	retinoid metabolic process
0.37	GO:0006027	glycosaminoglycan catabolic process
0.36	GO:0006024	glycosaminoglycan biosynthetic process
0.35	GO:0060071	Wnt signaling pathway, planar cell polarity pathway

0.77	GO:0043395	heparan sulfate proteoglycan binding
0.35	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

0.83	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0005783	endoplasmic reticulum
0.42	GO:0005796	Golgi lumen
0.42	GO:0005615	extracellular space
0.39	GO:0043202	lysosomal lumen
0.36	GO:0009897	external side of plasma membrane
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

sp|P51657|DHB1_RAT
Estradiol 17-beta-dehydrogenase 1
Search

HSD17B1

0.89	17-beta hydroxysteroid dehydrogenase type 1 splice variant

0.82	GO:0006703	estrogen biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0008209	androgen metabolic process
0.43	GO:0061370	testosterone biosynthetic process
0.42	GO:0060348	bone development
0.42	GO:0071248	cellular response to metal ion
0.35	GO:0015937	coenzyme A biosynthetic process
0.34	GO:0042572	retinol metabolic process
0.33	GO:0007601	visual perception
0.33	GO:0016310	phosphorylation

0.81	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.47	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.43	GO:1903924	estradiol binding
0.39	GO:0070401	NADP+ binding
0.36	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.36	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.36	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.35	GO:0004140	dephospho-CoA kinase activity
0.34	GO:0004745	retinol dehydrogenase activity
0.34	GO:0031132	serine 3-dehydrogenase activity

0.48

GO:0005829

cytosol

0.81	EC:1.1.1.62	GO:0004303
0.47	KEGG:R01836	GO:0047035

sp|P51672|XCL1_RAT
Lymphotactin
Search

XCL1

0.96	Viral Lymphotactin

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.65	GO:2000557	regulation of immunoglobulin production in mucosal tissue
0.65	GO:2000554	regulation of T-helper 1 cell cytokine production
0.64	GO:2000412	positive regulation of thymocyte migration
0.64	GO:0072676	lymphocyte migration
0.64	GO:2000537	regulation of B cell chemotaxis
0.64	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation
0.63	GO:2000503	positive regulation of natural killer cell chemotaxis
0.63	GO:2000553	positive regulation of T-helper 2 cell cytokine production

0.84	GO:0008009	chemokine activity
0.56	GO:0048020	CCR chemokine receptor binding
0.40	GO:0042803	protein homodimerization activity

0.66	GO:0005576	extracellular region
0.30	GO:0005623	cell

sp|P51673|RABP2_RAT
Cellular retinoic acid-binding protein 2
Search

CRABP2

0.94	Cellular retinoic acid binding protein I

0.75	GO:0042573	retinoic acid metabolic process
0.73	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.68	GO:0042363	fat-soluble vitamin catabolic process
0.68	GO:0016103	diterpenoid catabolic process
0.57	GO:0072329	monocarboxylic acid catabolic process
0.57	GO:0048672	positive regulation of collateral sprouting
0.55	GO:0035115	embryonic forelimb morphogenesis
0.43	GO:0021575	hindbrain morphogenesis
0.35	GO:0016102	diterpenoid biosynthetic process
0.34	GO:0008544	epidermis development

0.85	GO:0001972	retinoic acid binding
0.46	GO:0019841	retinol binding
0.45	GO:0016918	retinal binding
0.37	GO:0019215	intermediate filament binding
0.34	GO:0030332	cyclin binding
0.34	GO:0005198	structural molecule activity
0.33	GO:0042802	identical protein binding

0.51	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.46	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0070852	cell body fiber
0.36	GO:0070062	extracellular exosome
0.36	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0030424	axon
0.35	GO:0099512	supramolecular fiber

sp|P51740|PPBI2_RAT
Intestinal-type alkaline phosphatase 2
Search

0.48	Intestinal-type alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.41	GO:0071773	cellular response to BMP stimulus
0.38	GO:0006501	C-terminal protein lipidation
0.37	GO:0009612	response to mechanical stimulus
0.35	GO:0007586	digestion
0.35	GO:0006654	phosphatidic acid biosynthetic process
0.35	GO:0033280	response to vitamin D

0.80	GO:0004035	alkaline phosphatase activity
0.45	GO:0002020	protease binding
0.39	GO:0000287	magnesium ion binding
0.39	GO:0008270	zinc ion binding
0.35	GO:0042803	protein homodimerization activity
0.32	GO:0016462	pyrophosphatase activity

0.43	GO:0009986	cell surface
0.42	GO:0031225	anchored component of membrane
0.41	GO:0005886	plasma membrane
0.39	GO:0098552	side of membrane
0.38	GO:0030016	myofibril
0.35	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.80

EC:3.1.3.1

GO:0004035

sp|P51774|EGR2_RAT
E3 SUMO-protein ligase EGR2
Search

EGR2

0.74	Early growth response protein 2

0.64	GO:0021666	rhombomere 5 formation
0.64	GO:0021660	rhombomere 3 formation
0.62	GO:0035283	central nervous system segmentation
0.61	GO:0021612	facial nerve structural organization
0.59	GO:0014037	Schwann cell differentiation
0.59	GO:0007622	rhythmic behavior
0.59	GO:0006611	protein export from nucleus
0.59	GO:0035914	skeletal muscle cell differentiation
0.59	GO:0008045	motor neuron axon guidance
0.58	GO:0045444	fat cell differentiation

0.59	GO:0001102	RNA polymerase II activating transcription factor binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0003682	chromatin binding
0.53	GO:0046872	metal ion binding
0.44	GO:0071837	HMG box domain binding
0.43	GO:0016874	ligase activity

0.61	GO:0005634	nucleus
0.50	GO:0043233	organelle lumen
0.45	GO:0044446	intracellular organelle part
0.40	GO:0005737	cytoplasm

0.43

GO:0016874

sp|P51792|CLCN3_RAT
H(+)/Cl(-) exchange transporter 3
Search

CLCN3

0.51	Chloride channel protein (Fragment)

0.76	GO:1902476	chloride transmembrane transport
0.56	GO:0045794	negative regulation of cell volume

0.78	GO:0005247	voltage-gated chloride channel activity
0.57	GO:0072320	volume-sensitive chloride channel activity
0.53	GO:0030165	PDZ domain binding
0.48	GO:0046982	protein heterodimerization activity

0.54	GO:0042581	specific granule
0.52	GO:0045335	phagocytic vesicle
0.51	GO:0005770	late endosome
0.51	GO:0005769	early endosome
0.51	GO:0008021	synaptic vesicle
0.51	GO:0009897	external side of plasma membrane
0.49	GO:0012506	vesicle membrane
0.47	GO:0005794	Golgi apparatus
0.40	GO:0005887	integral component of plasma membrane

sp|P51794|CLCN4_RAT
H(+)/Cl(-) exchange transporter 4
Search

CLCN4

0.52	Chloride channel protein (Fragment)

0.76

GO:1902476

chloride transmembrane transport

0.77	GO:0005247	voltage-gated chloride channel activity
0.47	GO:0015297	antiporter activity
0.41	GO:0042802	identical protein binding

0.48	GO:0012505	endomembrane system
0.45	GO:0031984	organelle subcompartment
0.43	GO:0045177	apical part of cell
0.42	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0044444	cytoplasmic part
0.40	GO:0005887	integral component of plasma membrane
0.35	GO:0097708	intracellular vesicle

sp|P51796|CLCN5_RAT
H(+)/Cl(-) exchange transporter 5
Search

CLCN5

0.57	H(+)/Cl(-) exchange transporter 5

0.77	GO:1902476	chloride transmembrane transport
0.49	GO:0006897	endocytosis
0.49	GO:0007588	excretion

0.78	GO:0005247	voltage-gated chloride channel activity
0.67	GO:0015297	antiporter activity
0.54	GO:0042802	identical protein binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0010008	endosome membrane
0.67	GO:0000139	Golgi membrane
0.58	GO:0045177	apical part of cell
0.56	GO:0005887	integral component of plasma membrane
0.53	GO:0005765	lysosomal membrane
0.47	GO:0005829	cytosol
0.45	GO:0005770	late endosome
0.45	GO:0005769	early endosome
0.42	GO:0005789	endoplasmic reticulum membrane

sp|P51799|CLCN7_RAT
H(+)/Cl(-) exchange transporter 7
Search

CLCN7

0.51	Chloride voltage-gated channel 7

0.76	GO:1902476	chloride transmembrane transport
0.35	GO:0009268	response to pH

0.77

GO:0005247

voltage-gated chloride channel activity

0.47	GO:0005654	nucleoplasm
0.34	GO:0031410	cytoplasmic vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P51802|CLCKB_RAT
Chloride channel protein ClC-Kb
Search

0.51	Chloride voltage-gated channel Ka

0.77	GO:1902476	chloride transmembrane transport
0.43	GO:0034765	regulation of ion transmembrane transport
0.41	GO:0072053	renal inner medulla development
0.39	GO:0050878	regulation of body fluid levels
0.38	GO:0007588	excretion
0.37	GO:0030321	transepithelial chloride transport
0.36	GO:0051592	response to calcium ion
0.35	GO:0009268	response to pH
0.35	GO:0009414	response to water deprivation
0.34	GO:0046903	secretion

0.78	GO:0005247	voltage-gated chloride channel activity
0.39	GO:0042802	identical protein binding
0.37	GO:0046872	metal ion binding

0.45	GO:0034707	chloride channel complex
0.39	GO:0016323	basolateral plasma membrane
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:0012505	endomembrane system
0.35	GO:0016324	apical plasma membrane
0.35	GO:0030054	cell junction
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part

sp|P51839|GUC2D_RAT
Olfactory guanylyl cyclase GC-D
Search

0.57	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.47	GO:0007601	visual perception
0.46	GO:0050962	detection of light stimulus involved in sensory perception
0.45	GO:0035845	photoreceptor cell outer segment organization
0.43	GO:0009584	detection of visible light
0.34	GO:0006898	receptor-mediated endocytosis

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004016	adenylate cyclase activity
0.35	GO:0005044	scavenger receptor activity

0.50	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

sp|P51840|GUC2E_RAT
Guanylyl cyclase GC-E
Search

GUCY2D

0.57	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.47	GO:0007601	visual perception
0.45	GO:0050962	detection of light stimulus involved in sensory perception
0.44	GO:0035845	photoreceptor cell outer segment organization
0.43	GO:0009584	detection of visible light

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004016	adenylate cyclase activity

0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

sp|P51842|GUC2F_RAT
Retinal guanylyl cyclase 2
Search

GUCY2F

0.57	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.50	GO:0007601	visual perception
0.49	GO:0050962	detection of light stimulus involved in sensory perception
0.47	GO:0009584	detection of visible light
0.45	GO:0035845	photoreceptor cell outer segment organization

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004016	adenylate cyclase activity

0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

sp|P51868|CASQ2_RAT
Calsequestrin-2
Search

CASQ2

0.90	Calsequestrin

0.58	GO:0051208	sequestering of calcium ion
0.58	GO:0071313	cellular response to caffeine
0.58	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.58	GO:0010649	regulation of cell communication by electrical coupling
0.57	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.57	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.56	GO:1901017	negative regulation of potassium ion transmembrane transporter activity
0.55	GO:0060306	regulation of membrane repolarization
0.55	GO:0045214	sarcomere organization
0.55	GO:0060048	cardiac muscle contraction

0.70	GO:0005509	calcium ion binding
0.55	GO:0048306	calcium-dependent protein binding
0.38	GO:0042802	identical protein binding
0.35	GO:0046983	protein dimerization activity
0.35	GO:0005080	protein kinase C binding
0.34	GO:0030955	potassium ion binding
0.33	GO:0000287	magnesium ion binding
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding

0.60	GO:0033018	sarcoplasmic reticulum lumen
0.56	GO:0030314	junctional membrane complex
0.54	GO:0030018	Z disc
0.42	GO:0014802	terminal cisterna
0.36	GO:0033017	sarcoplasmic reticulum membrane
0.36	GO:0005891	voltage-gated calcium channel complex
0.36	GO:0005759	mitochondrial matrix

0.32

GO:0016887

sp|P51869|CP4F4_RAT
Cytochrome P450 4F4
Search

0.86	Cytochrome P450, family 4, subfamily F, polypeptide 2

0.63	GO:0042361	menaquinone catabolic process
0.63	GO:0042377	vitamin K catabolic process
0.62	GO:0042376	phylloquinone catabolic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006631	fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.58	GO:0005504	fatty acid binding

0.30

GO:0031224

intrinsic component of membrane

0.68

GO:0016705

sp|P51870|CP4F5_RAT
Cytochrome P450 4F5
Search

0.92	Cytochrome P450 family 4 subfamily F member 3

0.57	GO:0036102	leukotriene B4 metabolic process
0.57	GO:0036100	leukotriene catabolic process
0.54	GO:0042758	long-chain fatty acid catabolic process
0.53	GO:0003095	pressure natriuresis
0.53	GO:0006775	fat-soluble vitamin metabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0003091	renal water homeostasis
0.51	GO:0019373	epoxygenase P450 pathway
0.50	GO:0055078	sodium ion homeostasis
0.49	GO:0000038	very long-chain fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0005504	fatty acid binding
0.41	GO:0019825	oxygen binding
0.34	GO:0003676	nucleic acid binding

0.48	GO:0016324	apical plasma membrane
0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P51871|CP4F6_RAT
Cytochrome P450 4F6
Search

0.86	Cytochrome P450 family 4 subfamily F member 2

0.58	GO:0036102	leukotriene B4 metabolic process
0.58	GO:0036100	leukotriene catabolic process
0.55	GO:0042758	long-chain fatty acid catabolic process
0.54	GO:0003095	pressure natriuresis
0.54	GO:0006775	fat-soluble vitamin metabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0003091	renal water homeostasis
0.51	GO:0019373	epoxygenase P450 pathway
0.50	GO:0055078	sodium ion homeostasis
0.49	GO:0000038	very long-chain fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0005504	fatty acid binding
0.41	GO:0019825	oxygen binding
0.34	GO:0003676	nucleic acid binding

0.48	GO:0016324	apical plasma membrane
0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P51882|CD5_RAT
T-cell surface glycoprotein CD5
Search

CD5

0.97	T-cell surface glycoprotein CD5

0.72	GO:0006898	receptor-mediated endocytosis
0.63	GO:0031295	T cell costimulation
0.59	GO:0097190	apoptotic signaling pathway
0.36	GO:0009966	regulation of signal transduction
0.36	GO:0008037	cell recognition
0.36	GO:0008283	cell proliferation

0.81	GO:0005044	scavenger receptor activity
0.38	GO:0005515	protein binding
0.35	GO:0099600	transmembrane receptor activity
0.34	GO:0038023	signaling receptor activity

0.59	GO:0009897	external side of plasma membrane
0.39	GO:0044214	spanning component of plasma membrane

sp|P51886|LUM_RAT
Lumican
Search

LUM

0.97	Keratan sulfate proteoglycan lumican

0.84	GO:0030199	collagen fibril organization
0.73	GO:0007601	visual perception
0.59	GO:0032914	positive regulation of transforming growth factor beta1 production
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0007409	axonogenesis
0.42	GO:0048596	embryonic camera-type eye morphogenesis
0.38	GO:0051216	cartilage development
0.38	GO:0070848	response to growth factor
0.37	GO:0042340	keratan sulfate catabolic process
0.37	GO:0014070	response to organic cyclic compound

0.57	GO:0005518	collagen binding
0.35	GO:0005201	extracellular matrix structural constituent
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.55	GO:0005615	extracellular space
0.54	GO:0044420	extracellular matrix component
0.53	GO:0005581	collagen trimer
0.50	GO:0099512	supramolecular fiber
0.37	GO:0043202	lysosomal lumen
0.37	GO:1903561	extracellular vesicle
0.37	GO:0005796	Golgi lumen
0.30	GO:0016020	membrane

sp|P51907|EAA3_RAT
Excitatory amino acid transporter 3
Search

SLC1A1

0.45	Amino acid transporter

0.61	GO:1903712	cysteine transmembrane transport
0.61	GO:0140009	L-aspartate import across plasma membrane
0.61	GO:0140016	D-aspartate import across plasma membrane
0.60	GO:0098712	L-glutamate import across plasma membrane
0.58	GO:0010460	positive regulation of heart rate
0.53	GO:1902476	chloride transmembrane transport
0.52	GO:0051260	protein homooligomerization
0.36	GO:0014047	glutamate secretion
0.34	GO:0007268	chemical synaptic transmission

0.72	GO:0015293	symporter activity
0.61	GO:0033229	cysteine transmembrane transporter activity
0.56	GO:0005313	L-glutamate transmembrane transporter activity
0.53	GO:0015108	chloride transmembrane transporter activity
0.51	GO:0015081	sodium ion transmembrane transporter activity
0.49	GO:0022853	active ion transmembrane transporter activity
0.40	GO:0016595	glutamate binding
0.35	GO:0005515	protein binding
0.35	GO:0046872	metal ion binding

0.55	GO:0016324	apical plasma membrane
0.48	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome

sp|P51952|CDK7_RAT
Cyclin-dependent kinase 7 (Fragment)
Search

CDK7

0.95	Cell division protein kinase 7

0.61	GO:0006468	protein phosphorylation
0.53	GO:0050821	protein stabilization
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0006366	transcription by RNA polymerase II
0.45	GO:0051726	regulation of cell cycle
0.42	GO:0051301	cell division
0.37	GO:0007049	cell cycle
0.36	GO:0022414	reproductive process
0.36	GO:1900195	positive regulation of oocyte maturation
0.36	GO:0006294	nucleotide-excision repair, preincision complex assembly

0.80	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.55	GO:0008022	protein C-terminus binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.49	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0050681	androgen receptor binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0032403	protein complex binding

0.80	GO:0070985	TFIIK complex
0.58	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.37	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0042585	germinal vesicle
0.34	GO:0005856	cytoskeleton
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.80

EC:2.7.11.23

GO:0008353

sp|P51974|PAX8_RAT
Paired box protein Pax-8
Search

PAX8

0.83	Paired box protein Pax-8

0.69	GO:0007275	multicellular organism development
0.61	GO:2000611	positive regulation of thyroid hormone generation
0.60	GO:2000612	regulation of thyroid-stimulating hormone secretion
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1900218	negative regulation of apoptotic process involved in metanephric nephron tubule development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0071371	cellular response to gonadotropin stimulus
0.57	GO:0060231	mesenchymal to epithelial transition
0.56	GO:0010468	regulation of gene expression

0.56	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.40	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0004996	thyroid-stimulating hormone receptor activity
0.36	GO:0035326	enhancer binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex

sp|P52020|ERG1_RAT
Squalene monooxygenase
Search

SQLE

0.85	Squalene monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0008203	cholesterol metabolic process
0.48	GO:0016126	sterol biosynthetic process
0.39	GO:0010033	response to organic substance
0.36	GO:1902653	secondary alcohol biosynthetic process
0.36	GO:0045540	regulation of cholesterol biosynthetic process
0.34	GO:0006725	cellular aromatic compound metabolic process
0.34	GO:0008204	ergosterol metabolic process
0.34	GO:0044108	cellular alcohol biosynthetic process
0.34	GO:0016129	phytosteroid biosynthetic process

0.85	GO:0004506	squalene monooxygenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0043023	ribosomal large subunit binding
0.33	GO:0043022	ribosome binding
0.33	GO:0003743	translation initiation factor activity
0.32	GO:0008144	drug binding

0.45	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0031090	organelle membrane
0.34	GO:0005811	lipid droplet
0.33	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

0.85	EC:1.14.13.132	GO:0004506
0.85	KEGG:R02874	GO:0004506

sp|P52164|MAX_RAT
Protein max
Search

MAX

0.95	MYC associated factor X

0.52

GO:0000122

negative regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.57	GO:0070888	E-box binding
0.56	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.76	GO:0090575	RNA polymerase II transcription factor complex
0.51	GO:0000790	nuclear chromatin
0.50	GO:0032993	protein-DNA complex

sp|P52188|KCJ12_RAT
ATP-sensitive inward rectifier potassium channel 12
Search

KCNJ12

0.80	Inwardly-rectifying potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.41	GO:0098660	inorganic ion transmembrane transport
0.40	GO:0051289	protein homotetramerization
0.36	GO:0061337	cardiac conduction
0.35	GO:0006936	muscle contraction

0.84	GO:0005242	inward rectifier potassium channel activity
0.42	GO:0030165	PDZ domain binding

0.43	GO:0005887	integral component of plasma membrane
0.41	GO:0016323	basolateral plasma membrane
0.35	GO:0030315	T-tubule
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.33	GO:0045211	postsynaptic membrane
0.33	GO:0034705	potassium channel complex
0.33	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0030054	cell junction

sp|P52190|KCNJ4_RAT
Inward rectifier potassium channel 4
Search

KCNJ4

0.97	Inward rectifier potassium channel 4

0.74	GO:0034765	regulation of ion transmembrane transport
0.68	GO:0006813	potassium ion transport
0.59	GO:0098655	cation transmembrane transport
0.36	GO:0098660	inorganic ion transmembrane transport
0.36	GO:0071260	cellular response to mechanical stimulus
0.36	GO:0061337	cardiac conduction
0.35	GO:0051289	protein homotetramerization

0.80	GO:0005242	inward rectifier potassium channel activity
0.45	GO:0030165	PDZ domain binding

0.44	GO:0016323	basolateral plasma membrane
0.40	GO:0045211	postsynaptic membrane
0.39	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0030054	cell junction
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0034705	potassium channel complex

sp|P52191|KCJ16_RAT
Inward rectifier potassium channel 16
Search

KCNJ16

0.97	Inward rectifier potassium channel 16

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.33	GO:0032012	regulation of ARF protein signal transduction
0.32	GO:0065009	regulation of molecular function
0.30	GO:0009987	cellular process

0.84	GO:0005242	inward rectifier potassium channel activity
0.34	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator

0.44	GO:0005886	plasma membrane
0.35	GO:0034705	potassium channel complex

sp|P52287|GBB3_RAT
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Search

GNB3

0.97	GTP-binding protein beta-3 subunit

0.61	GO:0007165	signal transduction
0.47	GO:0060041	retina development in camera-type eye
0.46	GO:0050909	sensory perception of taste
0.46	GO:0008283	cell proliferation
0.38	GO:0010659	cardiac muscle cell apoptotic process
0.38	GO:0070208	protein heterotrimerization
0.37	GO:0071456	cellular response to hypoxia
0.37	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.36	GO:0071417	cellular response to organonitrogen compound
0.35	GO:0032870	cellular response to hormone stimulus

0.54	GO:0051020	GTPase binding
0.44	GO:0032403	protein complex binding
0.43	GO:0003924	GTPase activity
0.42	GO:0030507	spectrin binding
0.38	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.38	GO:0031702	type 1 angiotensin receptor binding
0.38	GO:0004871	signal transducer activity

0.56	GO:0043005	neuron projection
0.55	GO:0120038	plasma membrane bounded cell projection part
0.53	GO:0036477	somatodendritic compartment
0.47	GO:0097731	9+0 non-motile cilium
0.47	GO:1905360	GTPase complex
0.47	GO:0043209	myelin sheath
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0098797	plasma membrane protein complex
0.41	GO:0044297	cell body
0.39	GO:0044422	organelle part

0.38

EC:3.1.4.39

GO:0047391

sp|P52296|IMB1_RAT
Importin subunit beta-1
Search

KPNB1

0.85	Karyopherin subunit beta 1

0.71	GO:0007079	mitotic chromosome movement towards spindle pole
0.70	GO:0006610	ribosomal protein import into nucleus
0.70	GO:0031291	Ran protein signal transduction
0.70	GO:0030953	astral microtubule organization
0.69	GO:0006886	intracellular protein transport
0.66	GO:0007080	mitotic metaphase plate congression
0.66	GO:0090307	mitotic spindle assembly
0.66	GO:0040001	establishment of mitotic spindle localization
0.53	GO:0006607	NLS-bearing protein import into nucleus

0.80	GO:0008536	Ran GTPase binding
0.66	GO:0051879	Hsp90 protein binding
0.61	GO:0019904	protein domain specific binding
0.57	GO:0008565	protein transporter activity
0.53	GO:0008139	nuclear localization sequence binding

0.67	GO:0071782	endoplasmic reticulum tubular network
0.64	GO:0031965	nuclear membrane
0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol
0.51	GO:0034399	nuclear periphery
0.49	GO:0043234	protein complex

sp|P52303|AP1B1_RAT
AP-1 complex subunit beta-1
Search

AP1B1

0.64	AP complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.51	GO:0007368	determination of left/right symmetry
0.50	GO:0048513	animal organ development
0.49	GO:0072359	circulatory system development
0.44	GO:0048882	lateral line development
0.44	GO:0050974	detection of mechanical stimulus involved in sensory perception
0.44	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.44	GO:0035315	hair cell differentiation
0.44	GO:1903076	regulation of protein localization to plasma membrane

0.79	GO:0030276	clathrin binding
0.49	GO:0019901	protein kinase binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0005215	transporter activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0030131	clathrin adaptor complex
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.37	GO:0030665	clathrin-coated vesicle membrane
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P52481|CAP2_RAT
Adenylyl cyclase-associated protein 2
Search

CAP2

0.74	Adenylyl cyclase-associated protein 2

0.71	GO:0007010	cytoskeleton organization
0.59	GO:0030029	actin filament-based process
0.51	GO:0000902	cell morphogenesis
0.51	GO:0045761	regulation of adenylate cyclase activity
0.49	GO:0007163	establishment or maintenance of cell polarity
0.47	GO:0097435	supramolecular fiber organization
0.47	GO:0001667	ameboidal-type cell migration
0.43	GO:0006898	receptor-mediated endocytosis
0.42	GO:0007165	signal transduction
0.37	GO:0007190	activation of adenylate cyclase activity

0.74	GO:0003779	actin binding
0.53	GO:0008179	adenylate cyclase binding
0.50	GO:0042802	identical protein binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.55	GO:0014069	postsynaptic density
0.54	GO:0030864	cortical actin cytoskeleton
0.44	GO:0005615	extracellular space
0.36	GO:0005886	plasma membrane
0.35	GO:0005925	focal adhesion
0.35	GO:1903561	extracellular vesicle
0.35	GO:0035578	azurophil granule lumen
0.33	GO:0015934	large ribosomal subunit
0.33	GO:0005829	cytosol

sp|P52500|GRPR_RAT
Gastrin-releasing peptide receptor
Search

GRPR

0.97	Gastrin-releasing peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0036343	psychomotor behavior
0.56	GO:0035176	social behavior
0.51	GO:0042127	regulation of cell proliferation
0.48	GO:0043207	response to external biotic stimulus
0.35	GO:0007611	learning or memory
0.34	GO:0008283	cell proliferation

0.79	GO:0008528	G-protein coupled peptide receptor activity
0.36	GO:0042923	neuropeptide binding
0.33	GO:0005515	protein binding

0.48	GO:0005887	integral component of plasma membrane
0.37	GO:0005829	cytosol

sp|P52504|NDUS6_RAT
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
Search

NDUFS6

0.94	Mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 6

0.72	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.56	GO:0070584	mitochondrion morphogenesis
0.55	GO:0035264	multicellular organism growth
0.54	GO:0010259	multicellular organism aging
0.54	GO:0006936	muscle contraction
0.52	GO:0072358	cardiovascular system development
0.52	GO:0061458	reproductive system development
0.47	GO:0006631	fatty acid metabolic process
0.36	GO:0032981	mitochondrial respiratory chain complex I assembly

0.35	GO:0003954	NADH dehydrogenase activity
0.34	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.34	GO:0009055	electron transfer activity

0.79

GO:0005747

mitochondrial respiratory chain complex I

0.35

EC:1.6.99.3

GO:0003954

sp|P52555|ERP29_RAT
Endoplasmic reticulum resident protein 29
Search

ERP29

0.97	Endoplasmic reticulum resident protein 29

0.70	GO:0009306	protein secretion
0.67	GO:0000187	activation of MAPK activity
0.67	GO:0050709	negative regulation of protein secretion
0.63	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.58	GO:0010628	positive regulation of gene expression
0.55	GO:0010629	negative regulation of gene expression
0.48	GO:0006886	intracellular protein transport
0.48	GO:0006457	protein folding
0.37	GO:0034976	response to endoplasmic reticulum stress
0.37	GO:0043335	protein unfolding

0.42	GO:0051087	chaperone binding
0.42	GO:0042803	protein homodimerization activity
0.37	GO:0003756	protein disulfide isomerase activity
0.34	GO:0016887	ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0005788	endoplasmic reticulum lumen
0.71	GO:0042470	melanosome
0.61	GO:0009986	cell surface
0.45	GO:0005790	smooth endoplasmic reticulum
0.43	GO:0030133	transport vesicle
0.40	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:5.3.4.1

GO:0003756

sp|P52590|NU107_RAT
Nuclear pore complex protein Nup107
Search

NUP107

0.91	Nucleoporin 107

0.77	GO:0051292	nuclear pore complex assembly
0.72	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.69	GO:0008585	female gonad development
0.68	GO:0051028	mRNA transport
0.67	GO:0006405	RNA export from nucleus
0.57	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
0.53	GO:0006606	protein import into nucleus
0.50	GO:0010467	gene expression
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.80

GO:0017056

structural constituent of nuclear pore

0.78	GO:0005643	nuclear pore
0.67	GO:0034399	nuclear periphery
0.66	GO:0031965	nuclear membrane
0.65	GO:0000776	kinetochore
0.30	GO:0016021	integral component of membrane

sp|P52591|PO121_RAT
Nuclear envelope pore membrane protein POM 121
Search

POM121C

0.97	nuclear envelope pore membrane protein POM 121

0.59	GO:0006606	protein import into nucleus
0.56	GO:0006405	RNA export from nucleus
0.46	GO:0048268	clathrin coat assembly
0.45	GO:0007077	mitotic nuclear envelope disassembly
0.45	GO:0006915	apoptotic process
0.44	GO:1900034	regulation of cellular response to heat
0.44	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.44	GO:0006110	regulation of glycolytic process
0.44	GO:0051031	tRNA transport
0.43	GO:0060964	regulation of gene silencing by miRNA

0.62	GO:0008139	nuclear localization sequence binding
0.58	GO:0017056	structural constituent of nuclear pore
0.46	GO:0030276	clathrin binding
0.44	GO:0035091	phosphatidylinositol binding
0.44	GO:0003779	actin binding
0.41	GO:0008009	chemokine activity
0.35	GO:0032190	acrosin binding

0.63	GO:0044613	nuclear pore central transport channel
0.63	GO:0044615	nuclear pore nuclear basket
0.47	GO:0031965	nuclear membrane
0.45	GO:0030136	clathrin-coated vesicle
0.42	GO:0005654	nucleoplasm
0.40	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0044216	other organism cell
0.38	GO:0018995	host
0.38	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P52631|STAT3_RAT
Signal transducer and activator of transcription 3
Search

STAT3

0.69	Signal transducer and activator of transcription

0.61	GO:0007165	signal transduction
0.58	GO:1904685	positive regulation of metalloendopeptidase activity
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.57	GO:0072540	T-helper 17 cell lineage commitment
0.56	GO:0042755	eating behavior
0.56	GO:0048592	eye morphogenesis
0.56	GO:0060019	radial glial cell differentiation
0.56	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.56	GO:2001223	negative regulation of neuron migration

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001103	RNA polymerase II repressing transcription factor binding
0.55	GO:0003677	DNA binding
0.53	GO:0019903	protein phosphatase binding
0.51	GO:0019901	protein kinase binding
0.50	GO:0003682	chromatin binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0042803	protein homodimerization activity
0.39	GO:0031730	CCR5 chemokine receptor binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0005737	cytoplasm
0.48	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.41	GO:0005886	plasma membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|P52632|STA5B_RAT
Signal transducer and activator of transcription 5B
Search

STAT5B

0.70	Signal transducer and activator of transcription

0.86	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0046543	development of secondary female sexual characteristics
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0046544	development of secondary male sexual characteristics
0.56	GO:0045647	negative regulation of erythrocyte differentiation
0.56	GO:0001779	natural killer cell differentiation

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.52	GO:0035259	glucocorticoid receptor binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0046983	protein dimerization activity
0.39	GO:0003682	chromatin binding
0.35	GO:0004713	protein tyrosine kinase activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.35