Queries 13001 to 14000

GO:0003887

sp|O35799|HFE_RAT
Hereditary hemochromatosis protein homolog
Search

HFE

0.55	Hereditary hemochromatosis protein homolog

0.84	GO:0002626	negative regulation of T cell antigen processing and presentation
0.82	GO:0098711	iron ion import across plasma membrane
0.70	GO:0006879	cellular iron ion homeostasis
0.57	GO:1904283	negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
0.57	GO:2001186	negative regulation of CD8-positive, alpha-beta T cell activation
0.56	GO:1904440	positive regulation of ferrous iron import across plasma membrane
0.56	GO:1904435	regulation of transferrin receptor binding
0.56	GO:1904434	positive regulation of ferrous iron binding
0.55	GO:0002725	negative regulation of T cell cytokine production
0.55	GO:1900122	positive regulation of receptor binding

0.83	GO:1990459	transferrin receptor binding
0.55	GO:0030881	beta-2-microglobulin binding
0.55	GO:0039706	co-receptor binding
0.40	GO:0042605	peptide antigen binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0046703	natural killer cell lectin-like receptor binding

0.81	GO:1990712	HFE-transferrin receptor complex
0.52	GO:0045178	basal part of cell
0.51	GO:0055037	recycling endosome
0.51	GO:0009897	external side of plasma membrane
0.50	GO:0045177	apical part of cell
0.50	GO:0005769	early endosome
0.50	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005615	extracellular space
0.43	GO:0042612	MHC class I protein complex
0.41	GO:1990357	terminal web

sp|O35800|HIF1A_RAT
Hypoxia-inducible factor 1-alpha
Search

HIF1A

0.89	Hypoxia inducible factor 1 alpha subunit

0.61	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.61	GO:0051541	elastin metabolic process
0.61	GO:0060574	intestinal epithelial cell maturation
0.60	GO:0021502	neural fold elevation formation
0.60	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.60	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway
0.60	GO:0032364	oxygen homeostasis
0.60	GO:0019896	axonal transport of mitochondrion
0.60	GO:0001922	B-1 B cell homeostasis
0.60	GO:0010573	vascular endothelial growth factor production

0.66	GO:0046983	protein dimerization activity
0.62	GO:0035035	histone acetyltransferase binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0070888	E-box binding
0.57	GO:0051879	Hsp90 protein binding
0.56	GO:0042826	histone deacetylase binding
0.56	GO:0002039	p53 binding
0.55	GO:0035257	nuclear hormone receptor binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.58	GO:1904115	axon cytoplasm
0.54	GO:0031514	motile cilium
0.51	GO:0005667	transcription factor complex
0.50	GO:0043233	organelle lumen
0.49	GO:0005829	cytosol
0.45	GO:0044446	intracellular organelle part

sp|O35806|LTBP2_RAT
Latent-transforming growth factor beta-binding protein 2
Search

LTBP2

0.63	Latent transforming growth factor beta binding protein 2

0.51	GO:0097435	supramolecular fiber organization
0.41	GO:0060976	coronary vasculature development
0.41	GO:0035904	aorta development
0.41	GO:0003281	ventricular septum development
0.39	GO:0071363	cellular response to growth factor stimulus
0.38	GO:0071495	cellular response to endogenous stimulus
0.37	GO:0071559	response to transforming growth factor beta
0.37	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.37	GO:0071107	response to parathyroid hormone
0.37	GO:0071305	cellular response to vitamin D

0.70	GO:0005509	calcium ion binding
0.43	GO:0019838	growth factor binding
0.43	GO:0050436	microfibril binding
0.41	GO:0019955	cytokine binding
0.39	GO:0008201	heparin binding
0.35	GO:0005201	extracellular matrix structural constituent
0.32	GO:0005024	transforming growth factor beta-activated receptor activity

0.53	GO:0031012	extracellular matrix
0.52	GO:0005615	extracellular space
0.39	GO:0099512	supramolecular fiber
0.38	GO:0038045	large latent transforming growth factor-beta complex
0.37	GO:1903561	extracellular vesicle
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.36	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005739	mitochondrion
0.32	GO:0005788	endoplasmic reticulum lumen

sp|O35811|P2RY4_RAT
P2Y purinoceptor 4
Search

P2RY4

0.87	Neuropeptide FF receptor 2

0.84	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.80	GO:0030321	transepithelial chloride transport
0.60	GO:0070257	positive regulation of mucus secretion
0.58	GO:0071380	cellular response to prostaglandin E stimulus
0.58	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.56	GO:0097746	regulation of blood vessel diameter
0.36	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.35	GO:0060406	positive regulation of penile erection
0.35	GO:0032308	positive regulation of prostaglandin secretion
0.35	GO:0071415	cellular response to purine-containing compound

0.85	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.62	GO:0045030	UTP-activated nucleotide receptor activity
0.36	GO:0019103	pyrimidine nucleotide binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0031686	A1 adenosine receptor binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016787	hydrolase activity

0.41	GO:0016323	basolateral plasma membrane
0.41	GO:0016324	apical plasma membrane
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0005769	early endosome
0.34	GO:0005764	lysosome
0.33	GO:0005739	mitochondrion

0.32

GO:0016787

sp|O35814|STIP1_RAT
Stress-induced-phosphoprotein 1
Search

STIP1

0.78	stress-induced-phosphoprotein 1

0.43	GO:0007229	integrin-mediated signaling pathway
0.34	GO:0006412	translation

0.44	GO:0008483	transaminase activity
0.43	GO:0031072	heat shock protein binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.30	GO:0008022	protein C-terminus binding
0.30	GO:0051087	chaperone binding

0.70	GO:0043209	myelin sheath
0.54	GO:0043234	protein complex
0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.44

EC:2.6.1

GO:0008483

sp|O35815|ATX3_RAT
Ataxin-3
Search

ATXN3

0.89	Ataxin 3 variant ref

0.76	GO:0016579	protein deubiquitination
0.50	GO:0035640	exploration behavior
0.49	GO:0071218	cellular response to misfolded protein
0.49	GO:0010810	regulation of cell-substrate adhesion
0.47	GO:0034605	cellular response to heat
0.47	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.42	GO:1904327	protein localization to cytosolic proteasome complex
0.41	GO:1904294	positive regulation of ERAD pathway
0.40	GO:0045104	intermediate filament cytoskeleton organization

0.80	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0051117	ATPase binding
0.40	GO:0061578	Lys63-specific deubiquitinase activity
0.40	GO:1990380	Lys48-specific deubiquitinase activity
0.38	GO:0042802	identical protein binding
0.37	GO:0004407	histone deacetylase activity
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding

0.50	GO:0042405	nuclear inclusion body
0.45	GO:0005759	mitochondrial matrix
0.41	GO:0031966	mitochondrial membrane
0.41	GO:0005730	nucleolus
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.35	GO:0016363	nuclear matrix
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.5.1.98

GO:0004407

sp|O35817|AKA14_RAT
A-kinase anchor protein 14
Search

AKAP14

0.69	A-kinase anchor protein 14

0.51	GO:0007283	spermatogenesis
0.47	GO:0016310	phosphorylation
0.39	GO:0006402	mRNA catabolic process
0.39	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.38	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0006364	rRNA processing
0.37	GO:0008033	tRNA processing
0.37	GO:0006413	translational initiation
0.36	GO:0060377	negative regulation of mast cell differentiation
0.36	GO:0045403	negative regulation of interleukin-4 biosynthetic process

0.63	GO:0034237	protein kinase A regulatory subunit binding
0.49	GO:0016301	kinase activity
0.41	GO:0042302	structural constituent of cuticle
0.41	GO:0008995	ribonuclease E activity
0.39	GO:0003924	GTPase activity
0.39	GO:0005525	GTP binding
0.38	GO:0004521	endoribonuclease activity
0.38	GO:0003723	RNA binding
0.37	GO:0000287	magnesium ion binding
0.37	GO:0008270	zinc ion binding

0.61	GO:0005952	cAMP-dependent protein kinase complex
0.59	GO:0005930	axoneme
0.56	GO:0035686	sperm fibrous sheath
0.40	GO:0044459	plasma membrane part
0.39	GO:0098562	cytoplasmic side of membrane
0.37	GO:0009360	DNA polymerase III complex
0.35	GO:0017053	transcriptional repressor complex
0.34	GO:0005667	transcription factor complex
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.36

GO:0003887

sp|O35819|KLF6_RAT
Krueppel-like factor 6
Search

KLF6

0.97	Kruppel like factor 6

0.50	GO:0006366	transcription by RNA polymerase II
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0021634	optic nerve formation
0.41	GO:0043249	erythrocyte maturation
0.40	GO:0035265	organ growth
0.40	GO:0031016	pancreas development
0.40	GO:0001889	liver development
0.39	GO:0048565	digestive tract development
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0019221	cytokine-mediated signaling pathway

0.53	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001158	enhancer sequence-specific DNA binding
0.39	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38	GO:0003682	chromatin binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.53	GO:0001650	fibrillar center
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|O35820|DNPH1_RAT
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Search

DNPH1

0.94	2'-deoxynucleoside 5'-phosphate N-hydrolase 1

0.82	GO:0009159	deoxyribonucleoside monophosphate catabolic process
0.63	GO:0009116	nucleoside metabolic process
0.58	GO:0009117	nucleotide metabolic process
0.50	GO:0030855	epithelial cell differentiation
0.43	GO:0030307	positive regulation of cell growth
0.35	GO:0008283	cell proliferation
0.35	GO:0072523	purine-containing compound catabolic process
0.34	GO:0007021	tubulin complex assembly
0.34	GO:0007023	post-chaperonin tubulin folding pathway
0.33	GO:0043547	positive regulation of GTPase activity

0.82	GO:0070694	deoxyribonucleoside 5'-monophosphate N-glycosidase activity
0.82	GO:0050144	nucleoside deoxyribosyltransferase activity
0.54	GO:0042803	protein homodimerization activity
0.34	GO:0048487	beta-tubulin binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0016491	oxidoreductase activity

0.54	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.82

EC:3.2.2

GO:0070694

sp|O35821|MBB1A_RAT
Myb-binding protein 1A
Search

MYBBP1A

0.94	Myb-binding protein 1A

0.67	GO:2000210	positive regulation of anoikis
0.67	GO:0071897	DNA biosynthetic process
0.63	GO:0071158	positive regulation of cell cycle arrest
0.62	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.62	GO:0032922	circadian regulation of gene expression
0.61	GO:0042149	cellular response to glucose starvation
0.58	GO:0006351	transcription, DNA-templated
0.54	GO:0006913	nucleocytoplasmic transport
0.54	GO:0045892	negative regulation of transcription, DNA-templated
0.51	GO:0022904	respiratory electron transport chain

0.70	GO:0003887	DNA-directed DNA polymerase activity
0.60	GO:0001047	core promoter binding
0.59	GO:0003714	transcription corepressor activity
0.40	GO:0043565	sequence-specific DNA binding
0.38	GO:0008134	transcription factor binding
0.36	GO:0003723	RNA binding
0.35	GO:0008270	zinc ion binding

0.64	GO:0042564	NLS-dependent protein nuclear import complex
0.55	GO:0005730	nucleolus
0.41	GO:0005737	cytoplasm
0.35	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.70

GO:0003887

sp|O35824|DNJA2_RAT
DnaJ homolog subfamily A member 2
Search

DNAJA2

0.90	DnaJ like protein subfamily A member 2

0.67	GO:0006457	protein folding
0.65	GO:0009408	response to heat
0.54	GO:0032781	positive regulation of ATPase activity
0.37	GO:0018885	carbon tetrachloride metabolic process
0.35	GO:0008284	positive regulation of cell proliferation

0.75	GO:0031072	heat shock protein binding
0.70	GO:0051082	unfolded protein binding
0.54	GO:0001671	ATPase activator activity
0.52	GO:0046872	metal ion binding
0.52	GO:0051087	chaperone binding
0.49	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|O35826|GLCNE_RAT
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
Search

GNE

0.93	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

0.79	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.57	GO:0016310	phosphorylation
0.46	GO:0006045	N-acetylglucosamine biosynthetic process
0.40	GO:0006054	N-acetylneuraminate metabolic process
0.40	GO:0044262	cellular carbohydrate metabolic process
0.35	GO:0007155	cell adhesion
0.34	GO:0046394	carboxylic acid biosynthetic process

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.59	GO:0016301	kinase activity
0.46	GO:0008761	UDP-N-acetylglucosamine 2-epimerase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.37

GO:0005829

cytosol

0.66

EC:3.2.1

GO:0004553

sp|O35827|APBB3_RAT
Amyloid beta A4 precursor protein-binding family B member 3
Search

APBB3

0.97	Amyloid beta precursor protein binding family B member 3

0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.40	GO:0042981	regulation of apoptotic process
0.39	GO:0043069	negative regulation of programmed cell death
0.37	GO:0043068	positive regulation of programmed cell death
0.37	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006974	cellular response to DNA damage stimulus
0.33	GO:0030308	negative regulation of cell growth

0.67	GO:0001540	amyloid-beta binding
0.58	GO:0008134	transcription factor binding
0.39	GO:0070064	proline-rich region binding
0.37	GO:0042393	histone binding
0.37	GO:0003682	chromatin binding
0.36	GO:0005540	hyaluronic acid binding

0.69	GO:0015629	actin cytoskeleton
0.64	GO:0005829	cytosol
0.51	GO:0005634	nucleus
0.39	GO:0030426	growth cone
0.38	GO:0030027	lamellipodium
0.37	GO:0045202	synapse
0.34	GO:0005886	plasma membrane

sp|O35828|CORO7_RAT
Coronin-7
Search

CORO7

0.68

Coronin

0.53	GO:0007030	Golgi organization
0.52	GO:0030010	establishment of cell polarity
0.51	GO:0016477	cell migration
0.51	GO:0007015	actin filament organization
0.42	GO:0006895	Golgi to endosome transport
0.40	GO:0051258	protein polymerization
0.38	GO:0015031	protein transport

0.39

GO:0003779

actin binding

0.72	GO:0005794	Golgi apparatus
0.39	GO:0031410	cytoplasmic vesicle
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0005829	cytosol
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

sp|O35831|CDK17_RAT
Cyclin-dependent kinase 17
Search

CDK17

0.96	Serine/threonine-protein kinase PCTAIRE-2

0.63	GO:0006468	protein phosphorylation
0.36	GO:0051301	cell division
0.34	GO:0031175	neuron projection development
0.34	GO:0006887	exocytosis

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0060089	molecular transducer activity
0.33	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.34	GO:0098793	presynapse
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|O35832|CKD18_RAT
Cyclin-dependent kinase 18
Search

CDK18

0.93	PCTAIRE-motif protein kinase 3

0.63	GO:0006468	protein phosphorylation
0.36	GO:0051726	regulation of cell cycle
0.35	GO:0006368	transcription elongation from RNA polymerase II promoter
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0051301	cell division

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0097472	cyclin-dependent protein kinase activity
0.35	GO:0030332	cyclin binding
0.34	GO:0044212	transcription regulatory region DNA binding
0.34	GO:0008134	transcription factor binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.34	GO:0005694	chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.67

GO:0004674

sp|O35854|BCAT2_RAT
Branched-chain-amino-acid aminotransferase, mitochondrial
Search

BCAT2

0.49	Branched-chain-amino-acid aminotransferase

0.70	GO:0009081	branched-chain amino acid metabolic process
0.61	GO:0008652	cellular amino acid biosynthetic process
0.51	GO:1990830	cellular response to leukemia inhibitory factor
0.47	GO:0010817	regulation of hormone levels
0.45	GO:0009063	cellular amino acid catabolic process
0.45	GO:1901605	alpha-amino acid metabolic process
0.35	GO:0007595	lactation
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0008283	cell proliferation

0.78	GO:0004084	branched-chain-amino-acid transaminase activity
0.34	GO:0016491	oxidoreductase activity
0.33	GO:0042802	identical protein binding
0.33	GO:0019843	rRNA binding
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.78

EC:2.6.1.42

GO:0004084

sp|O35867|NEB1_RAT
Neurabin-1
Search

PPP1R9A

0.91	LOW QUALITY PROTEIN: neurabin-1

0.83	GO:0019722	calcium-mediated signaling
0.74	GO:0007015	actin filament organization
0.61	GO:0031175	neuron projection development
0.54	GO:1904049	negative regulation of spontaneous neurotransmitter secretion
0.52	GO:1900454	positive regulation of long term synaptic depression
0.52	GO:0051823	regulation of synapse structural plasticity
0.52	GO:1900272	negative regulation of long-term synaptic potentiation
0.51	GO:0051497	negative regulation of stress fiber assembly
0.51	GO:0060999	positive regulation of dendritic spine development
0.51	GO:0061001	regulation of dendritic spine morphogenesis

0.52	GO:0008157	protein phosphatase 1 binding
0.50	GO:0044325	ion channel binding
0.49	GO:0008022	protein C-terminus binding
0.47	GO:0019901	protein kinase binding
0.47	GO:0003779	actin binding
0.46	GO:0019904	protein domain specific binding
0.46	GO:0042803	protein homodimerization activity
0.46	GO:0032403	protein complex binding
0.46	GO:0051020	GTPase binding

0.85	GO:0043197	dendritic spine
0.84	GO:0030175	filopodium
0.80	GO:0030864	cortical actin cytoskeleton
0.65	GO:0030426	growth cone
0.49	GO:0031594	neuromuscular junction
0.49	GO:0014069	postsynaptic density
0.49	GO:0030027	lamellipodium
0.48	GO:0043025	neuronal cell body
0.44	GO:0005829	cytosol
0.43	GO:0030054	cell junction

sp|O35870|FANCC_RAT
Fanconi anemia group C protein homolog
Search

FANCC

0.97	Fanconi anemia complementation group C

0.64	GO:0006281	DNA repair
0.62	GO:0097150	neuronal stem cell population maintenance
0.61	GO:0048854	brain morphogenesis
0.60	GO:0002262	myeloid cell homeostasis
0.57	GO:0007281	germ cell development
0.56	GO:0034599	cellular response to oxidative stress
0.55	GO:0000303	response to superoxide
0.55	GO:0006801	superoxide metabolic process
0.54	GO:1901701	cellular response to oxygen-containing compound
0.51	GO:0098869	cellular oxidant detoxification

0.34

GO:0005515

protein binding

0.77	GO:0043240	Fanconi anaemia nuclear complex
0.51	GO:0005829	cytosol
0.36	GO:0000785	chromatin

sp|O35876|SMN_RAT
Survival motor neuron protein
Search

0.87	Survival of motor neuron

0.69	GO:0006397	mRNA processing
0.50	GO:0007399	nervous system development
0.49	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.49	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.49	GO:0000904	cell morphogenesis involved in differentiation
0.49	GO:0051960	regulation of nervous system development
0.49	GO:0060284	regulation of cell development
0.49	GO:0007019	microtubule depolymerization
0.48	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.48	GO:0033120	positive regulation of RNA splicing

0.59	GO:0003723	RNA binding
0.40	GO:0042802	identical protein binding
0.38	GO:0017134	fibroblast growth factor binding

0.61	GO:0005634	nucleus
0.50	GO:0032797	SMN complex
0.49	GO:0043204	perikaryon
0.49	GO:0034719	SMN-Sm protein complex
0.49	GO:0030018	Z disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0043005	neuron projection
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0005829	cytosol
0.41	GO:0044446	intracellular organelle part

sp|O35878|HSPB2_RAT
Heat shock protein beta-2
Search

HSPB2

0.97	Heat shock protein beta-2

0.65	GO:0007525	somatic muscle development
0.38	GO:0009408	response to heat
0.37	GO:0006986	response to unfolded protein
0.35	GO:0043085	positive regulation of catalytic activity
0.34	GO:0045766	positive regulation of angiogenesis
0.34	GO:0061077	chaperone-mediated protein folding

0.79	GO:0005212	structural constituent of eye lens
0.36	GO:0008047	enzyme activator activity
0.35	GO:0005515	protein binding

0.37	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

sp|O35881|P2Y14_RAT
P2Y purinoceptor 14
Search

P2RY14

0.97	Purinergic receptor P2Y G-protein coupled 14 transcript variant 2

0.85	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.46	GO:0007194	negative regulation of adenylate cyclase activity
0.46	GO:0007596	blood coagulation
0.40	GO:0001774	microglial cell activation
0.34	GO:0006955	immune response

0.85	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.36	GO:0045029	UDP-activated nucleotide receptor activity

0.44

GO:0005887

integral component of plasma membrane

sp|O35889|AFAD_RAT
Afadin
Search

AFDN

0.92	Afadin, adherens junction formation factor

0.60	GO:0007165	signal transduction
0.55	GO:0034332	adherens junction organization
0.53	GO:0070445	regulation of oligodendrocyte progenitor proliferation
0.53	GO:0060019	radial glial cell differentiation
0.52	GO:1902414	protein localization to cell junction
0.52	GO:0034331	cell junction maintenance
0.51	GO:0048854	brain morphogenesis
0.51	GO:0060563	neuroepithelial cell differentiation
0.51	GO:0021987	cerebral cortex development
0.48	GO:0048872	homeostasis of number of cells

0.52	GO:0050839	cell adhesion molecule binding
0.38	GO:0017016	Ras GTPase binding
0.36	GO:0030274	LIM domain binding
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0005911	cell-cell junction
0.52	GO:0005912	adherens junction
0.51	GO:0016607	nuclear speck
0.49	GO:0045177	apical part of cell
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane

sp|O35910|MOT4_RAT
Monocarboxylate transporter 4
Search

SLC16A3

0.95	Monocarboxylic acid transporter 4

0.81	GO:0035873	lactate transmembrane transport
0.35	GO:0050900	leukocyte migration
0.34	GO:0006090	pyruvate metabolic process

0.81	GO:0015129	lactate transmembrane transporter activity
0.37	GO:0015293	symporter activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.55	GO:0031965	nuclear membrane

sp|O35913|SO1A4_RAT
Solute carrier organic anion transporter family member 1A4
Search

SLCO1A2

0.61	Solute carrier organic anion transporter family member

0.58	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0071702	organic substance transport
0.42	GO:0010876	lipid localization
0.41	GO:0035634	response to stilbenoid
0.41	GO:0031100	animal organ regeneration
0.40	GO:0070327	thyroid hormone transport
0.40	GO:0033574	response to testosterone
0.38	GO:0050892	intestinal absorption
0.38	GO:0008206	bile acid metabolic process

0.56

GO:0005215

transporter activity

0.55	GO:0005886	plasma membrane
0.37	GO:0005903	brush border
0.36	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

sp|O35920|CAN9_RAT
Calpain-9
Search

CAPN9

0.95	Neutral protease calpain 9a

0.78	GO:0007586	digestion
0.61	GO:0006508	proteolysis
0.35	GO:0043066	negative regulation of apoptotic process
0.34	GO:0051493	regulation of cytoskeleton organization
0.33	GO:0051260	protein homooligomerization
0.32	GO:0045214	sarcomere organization

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.70	GO:0005509	calcium ion binding

0.45	GO:0005622	intracellular
0.37	GO:0097223	sperm part
0.36	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|O35921|EAA4_RAT
Excitatory amino acid transporter 4
Search

SLC1A6

0.45	Amino acid transporter

0.56	GO:0089711	L-glutamate transmembrane transport
0.50	GO:0042391	regulation of membrane potential
0.48	GO:0089718	amino acid import across plasma membrane
0.48	GO:1903802	L-glutamate(1-) import across plasma membrane
0.48	GO:0001504	neurotransmitter uptake
0.46	GO:0089712	L-aspartate transmembrane transport
0.45	GO:0070779	D-aspartate import
0.45	GO:0009449	gamma-aminobutyric acid biosynthetic process
0.44	GO:0031223	auditory behavior
0.43	GO:0021545	cranial nerve development

0.72	GO:0015293	symporter activity
0.56	GO:0005313	L-glutamate transmembrane transporter activity
0.45	GO:0016595	glutamate binding
0.43	GO:0015081	sodium ion transmembrane transporter activity
0.40	GO:0022853	active ion transmembrane transporter activity
0.36	GO:0015183	L-aspartate transmembrane transporter activity
0.35	GO:0046872	metal ion binding

0.51	GO:0045111	intermediate filament cytoskeleton
0.47	GO:0005794	Golgi apparatus
0.42	GO:0043025	neuronal cell body
0.41	GO:0043005	neuron projection
0.41	GO:0005887	integral component of plasma membrane
0.41	GO:0009986	cell surface
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0098794	postsynapse
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0019866	organelle inner membrane

sp|O35923|BRCA2_RAT
Breast cancer type 2 susceptibility protein homolog
Search

BRCA2

0.85	Breast cancer susceptibility protein 2

0.76	GO:0000724	double-strand break repair via homologous recombination
0.55	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.54	GO:0070200	establishment of protein localization to telomere
0.53	GO:0001833	inner cell mass cell proliferation
0.53	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.53	GO:0010225	response to UV-C
0.53	GO:0001556	oocyte maturation
0.53	GO:0007141	male meiosis I
0.52	GO:0010165	response to X-ray
0.52	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

0.52	GO:0010485	H4 histone acetyltransferase activity
0.52	GO:0010484	H3 histone acetyltransferase activity
0.51	GO:0002020	protease binding
0.51	GO:0043015	gamma-tubulin binding
0.50	GO:0008022	protein C-terminus binding
0.47	GO:0003697	single-stranded DNA binding
0.47	GO:0042802	identical protein binding

0.56	GO:0033593	BRCA2-MAGE-D1 complex
0.53	GO:0000800	lateral element
0.50	GO:0030141	secretory granule
0.50	GO:0000784	nuclear chromosome, telomeric region
0.49	GO:0005813	centrosome
0.43	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol

sp|O35932|PD2RL_RAT
Prostaglandin D2 receptor-like
Search

0.96	Prostaglandin E receptor 2

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0071379	cellular response to prostaglandin stimulus
0.60	GO:0034695	response to prostaglandin E
0.58	GO:1901655	cellular response to ketone
0.57	GO:0097306	cellular response to alcohol
0.49	GO:0032570	response to progesterone
0.49	GO:0097755	positive regulation of blood vessel diameter
0.49	GO:0019933	cAMP-mediated signaling
0.49	GO:0071798	response to prostaglandin D
0.48	GO:0032496	response to lipopolysaccharide

0.85	GO:0004954	prostanoid receptor activity
0.34	GO:0005515	protein binding
0.31	GO:0046872	metal ion binding

0.44	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|O35952|GLO2_RAT
Hydroxyacylglutathione hydrolase, mitochondrial
Search

HAGH

0.47	Mitochondrial hydroxyacylglutathione hydrolase

0.77	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
0.52	GO:0006750	glutathione biosynthetic process
0.35	GO:0019853	L-ascorbic acid biosynthetic process
0.35	GO:0007283	spermatogenesis
0.34	GO:0006090	pyruvate metabolic process

0.77	GO:0004416	hydroxyacylglutathione hydrolase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.42	GO:0005759	mitochondrial matrix
0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.77

EC:3.1.2.6

GO:0004416

sp|O35956|S22A6_RAT
Solute carrier family 22 member 6
Search

SLC22A6

0.87	Solute carrier family 22 (organic anion transporter), member 6, like

0.62	GO:0097254	renal tubular secretion
0.61	GO:0015742	alpha-ketoglutarate transport
0.53	GO:0043252	sodium-independent organic anion transport
0.53	GO:0055085	transmembrane transport
0.52	GO:0015698	inorganic anion transport
0.51	GO:0015747	urate transport
0.42	GO:0031427	response to methotrexate
0.39	GO:0051260	protein homooligomerization
0.33	GO:0009636	response to toxic substance
0.33	GO:0008643	carbohydrate transport

0.60	GO:0005452	inorganic anion exchanger activity
0.53	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.51	GO:0015143	urate transmembrane transporter activity
0.41	GO:0031404	chloride ion binding
0.40	GO:0015301	anion:anion antiporter activity
0.38	GO:0042803	protein homodimerization activity

0.58	GO:0016323	basolateral plasma membrane
0.50	GO:0005887	integral component of plasma membrane
0.40	GO:0005901	caveola
0.38	GO:0070062	extracellular exosome
0.36	GO:0043234	protein complex

sp|O35964|SH3G1_RAT
Endophilin-A2
Search

SH3GL1

0.95	Kinase C and casein kinase II substrate protein 3

0.71	GO:0006897	endocytosis
0.61	GO:0072318	clathrin coat disassembly
0.58	GO:0036465	synaptic vesicle recycling
0.57	GO:0099003	vesicle-mediated transport in synapse
0.47	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.47	GO:0030100	regulation of endocytosis
0.47	GO:0097484	dendrite extension
0.41	GO:1903421	regulation of synaptic vesicle recycling
0.41	GO:0098815	modulation of excitatory postsynaptic potential
0.39	GO:0099050	vesicle scission

0.53	GO:0042802	identical protein binding
0.53	GO:0045296	cadherin binding
0.42	GO:0031697	beta-1 adrenergic receptor binding
0.42	GO:0008022	protein C-terminus binding
0.40	GO:0044325	ion channel binding
0.40	GO:0019902	phosphatase binding
0.39	GO:0008289	lipid binding
0.39	GO:0017124	SH3 domain binding
0.38	GO:0051020	GTPase binding
0.36	GO:0019901	protein kinase binding

0.53	GO:0045202	synapse
0.49	GO:0005737	cytoplasm
0.44	GO:0097708	intracellular vesicle
0.42	GO:0012505	endomembrane system
0.41	GO:0002102	podosome
0.38	GO:0030054	cell junction
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0042995	cell projection
0.35	GO:0070062	extracellular exosome

tr|O35977|O35977_RAT
GDNF family receptor alpha 2
Search

GFRA2

0.97	GDNF family receptor alpha

0.50	GO:0007399	nervous system development
0.50	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.39	GO:0031953	negative regulation of protein autophosphorylation
0.36	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0048468	cell development
0.36	GO:0000165	MAPK cascade
0.36	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.35	GO:0006928	movement of cell or subcellular component
0.35	GO:0040011	locomotion

0.65	GO:0004872	receptor activity
0.36	GO:0004871	signal transducer activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0005102	receptor binding
0.34	GO:0050839	cell adhesion molecule binding
0.33	GO:0032403	protein complex binding

0.70	GO:0031225	anchored component of membrane
0.51	GO:0005886	plasma membrane
0.35	GO:0019898	extrinsic component of membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.33	GO:0043235	receptor complex
0.33	GO:0009986	cell surface
0.33	GO:0098552	side of membrane
0.32	GO:0098796	membrane protein complex

sp|O35986|ZRAB2_RAT
Zinc finger Ran-binding domain-containing protein 2
Search

ZRANB2

0.92	Zinc finger Ran-binding domain-containing protein 2

0.42	GO:0042742	defense response to bacterium
0.39	GO:0008380	RNA splicing
0.38	GO:0006397	mRNA processing
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.54	GO:0003723	RNA binding
0.53	GO:0046872	metal ion binding
0.46	GO:0030882	lipid antigen binding
0.43	GO:0001530	lipopolysaccharide binding
0.35	GO:0004960	thromboxane receptor activity
0.35	GO:0004957	prostaglandin E receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0016746	transferase activity, transferring acyl groups

0.57	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0016746

sp|O35987|NSF1C_RAT
NSFL1 cofactor p47
Search

NSFL1C

0.97	NSFL1 cofactor

0.67	GO:0031468	nuclear envelope reassembly
0.64	GO:0000045	autophagosome assembly
0.64	GO:0007030	Golgi organization
0.61	GO:0043666	regulation of phosphoprotein phosphatase activity
0.60	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.55	GO:0061025	membrane fusion

0.63	GO:0043130	ubiquitin binding
0.62	GO:0019888	protein phosphatase regulator activity
0.49	GO:0008289	lipid binding
0.48	GO:0051117	ATPase binding
0.38	GO:0043168	anion binding

0.77	GO:0045111	intermediate filament cytoskeleton
0.69	GO:0005829	cytosol
0.68	GO:0005654	nucleoplasm
0.55	GO:0005886	plasma membrane
0.52	GO:0005795	Golgi stack
0.51	GO:1990730	VCP-NSFL1C complex
0.46	GO:0005694	chromosome

sp|O54697|NALDL_RAT
N-acetylated-alpha-linked acidic dipeptidase-like protein
Search

NAALADL1

0.88	N-acetylated alpha-linked acidic dipeptidase like 1

0.47	GO:0006508	proteolysis
0.37	GO:0042135	neurotransmitter catabolic process

0.53	GO:0004180	carboxypeptidase activity
0.42	GO:0016805	dipeptidase activity
0.40	GO:0008237	metallopeptidase activity
0.39	GO:0050129	N-formylglutamate deformylase activity
0.36	GO:0046872	metal ion binding

0.43	GO:0016324	apical plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.42	EC:3.4.13	GO:0016805
0.39	KEGG:R00525	GO:0050129

sp|O54698|S29A1_RAT
Equilibrative nucleoside transporter 1
Search

SLC29A1

0.89	NBMPR-sensitive equilibrative nucleoside transporter

0.79	GO:1901642	nucleoside transmembrane transport
0.40	GO:0015862	uridine transport
0.39	GO:0007595	lactation
0.39	GO:0030431	sleep
0.39	GO:0071333	cellular response to glucose stimulus
0.39	GO:0071456	cellular response to hypoxia
0.38	GO:0060079	excitatory postsynaptic potential
0.32	GO:0006457	protein folding
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process

0.78	GO:0005337	nucleoside transmembrane transporter activity
0.32	GO:0051082	unfolded protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0005887	integral component of plasma membrane
0.53	GO:0016323	basolateral plasma membrane
0.52	GO:0016324	apical plasma membrane
0.38	GO:0098794	postsynapse

sp|O54699|S29A2_RAT
Equilibrative nucleoside transporter 2
Search

SLC29A2

0.89	Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter

0.79	GO:1901642	nucleoside transmembrane transport
0.39	GO:0015862	uridine transport
0.38	GO:0007595	lactation
0.38	GO:0035364	thymine transport
0.37	GO:0035344	hypoxanthine transport
0.37	GO:0015853	adenine transport
0.37	GO:0015854	guanine transport
0.36	GO:1901701	cellular response to oxygen-containing compound
0.36	GO:0071310	cellular response to organic substance
0.36	GO:0030431	sleep

0.78	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0005515	protein binding

0.66	GO:0005887	integral component of plasma membrane
0.57	GO:0016323	basolateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.37	GO:0031965	nuclear membrane
0.35	GO:0098794	postsynapse
0.34	GO:0005730	nucleolus

sp|O54701|NCKX2_RAT
Sodium/potassium/calcium exchanger 2
Search

SLC24A2

0.92	Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

0.75	GO:0007601	visual perception
0.74	GO:0035725	sodium ion transmembrane transport
0.71	GO:0060292	long term synaptic depression
0.68	GO:0060291	long-term synaptic potentiation
0.65	GO:0007613	memory
0.65	GO:0007612	learning
0.64	GO:0006874	cellular calcium ion homeostasis
0.62	GO:0070588	calcium ion transmembrane transport

0.83	GO:0008273	calcium, potassium:sodium antiporter activity
0.63	GO:0005262	calcium channel activity
0.49	GO:0031402	sodium ion binding
0.47	GO:0030955	potassium ion binding
0.45	GO:0005509	calcium ion binding

0.44

GO:0005887

integral component of plasma membrane

sp|O54702|CHSTA_RAT
Carbohydrate sulfotransferase 10
Search

CHST10

0.67	Carbohydrate sulfotransferase

0.66	GO:0016051	carbohydrate biosynthetic process
0.37	GO:0007616	long-term memory
0.37	GO:0007612	learning
0.34	GO:0007155	cell adhesion

0.77

GO:0008146

sulfotransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0008146

sp|O54715|VAS1_RAT
V-type proton ATPase subunit S1
Search

ATP6AP1

0.91	ATPase H+ transporting accessory protein 1

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.73	GO:2001206	positive regulation of osteoclast development
0.71	GO:0046852	positive regulation of bone remodeling
0.71	GO:0036295	cellular response to increased oxygen levels
0.70	GO:0045124	regulation of bone resorption
0.69	GO:0045669	positive regulation of osteoblast differentiation
0.68	GO:0045851	pH reduction
0.68	GO:0045921	positive regulation of exocytosis
0.67	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.66	GO:0032846	positive regulation of homeostatic process

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.65	GO:0017137	Rab GTPase binding
0.39	GO:0005093	Rab GDP-dissociation inhibitor activity

0.81	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.39	GO:0005886	plasma membrane
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|O54728|PLB1_RAT
Phospholipase B1, membrane-associated
Search

PLB1

0.65	Phospholipase B1, membrane-associated

0.54	GO:2000344	positive regulation of acrosome reaction
0.53	GO:0006629	lipid metabolic process
0.40	GO:1901575	organic substance catabolic process
0.36	GO:0006470	protein dephosphorylation
0.30	GO:0010817	regulation of hormone levels
0.30	GO:0044281	small molecule metabolic process
0.30	GO:1901615	organic hydroxy compound metabolic process
0.30	GO:0019637	organophosphate metabolic process

0.62	GO:0016298	lipase activity
0.47	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.47	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.36	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0046872	metal ion binding
0.30	GO:0050253	retinyl-palmitate esterase activity

0.46	GO:0016324	apical plasma membrane
0.30	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane
0.30	GO:0098862	cluster of actin-based cell projections

0.62	EC:3.1.1	GO:0016298
0.30	KEGG:R02368	GO:0050253

sp|O54735|PDE5A_RAT
cGMP-specific 3',5'-cyclic phosphodiesterase
Search

PDE5A

0.58	Phosphodiesterase

0.61	GO:0046069	cGMP catabolic process
0.60	GO:0007165	signal transduction
0.57	GO:0055118	negative regulation of cardiac muscle contraction
0.57	GO:0055119	relaxation of cardiac muscle
0.56	GO:0060282	positive regulation of oocyte development
0.55	GO:0014742	positive regulation of muscle hypertrophy
0.55	GO:0010611	regulation of cardiac muscle hypertrophy
0.55	GO:0030823	regulation of cGMP metabolic process
0.54	GO:0042130	negative regulation of T cell proliferation
0.52	GO:0043406	positive regulation of MAP kinase activity

0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.55	GO:0030553	cGMP binding
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.36

GO:0005829

cytosol

0.78

GO:0004114

sp|O54747|DPOD1_RAT
DNA polymerase delta catalytic subunit
Search

POLD1

0.48	DNA polymerase delta catalytic subunit

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0006287	base-excision repair, gap-filling
0.50	GO:0006297	nucleotide-excision repair, DNA gap filling
0.42	GO:0055089	fatty acid homeostasis
0.41	GO:0034644	cellular response to UV
0.36	GO:0042769	DNA damage response, detection of DNA damage
0.35	GO:0006301	postreplication repair
0.35	GO:0006283	transcription-coupled nucleotide-excision repair

0.71	GO:0008408	3'-5' exonuclease activity
0.70	GO:0003887	DNA-directed DNA polymerase activity
0.64	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0003677	DNA binding
0.52	GO:1901265	nucleoside phosphate binding
0.52	GO:0046872	metal ion binding
0.51	GO:0036094	small molecule binding
0.45	GO:0019899	enzyme binding
0.45	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.40	GO:0003682	chromatin binding

0.59	GO:0005634	nucleus
0.51	GO:0016235	aggresome
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0030894	replisome
0.44	GO:0005829	cytosol
0.44	GO:0042575	DNA polymerase complex
0.38	GO:0000781	chromosome, telomeric region
0.37	GO:1990391	DNA repair complex
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.70

GO:0003887

sp|O54748|STK3_RAT
Serine/threonine-protein kinase 3
Search

STK3

0.92	Serine/threonine-protein kinase 3

0.65	GO:0060800	regulation of cell differentiation involved in embryonic placenta development
0.64	GO:0097284	hepatocyte apoptotic process
0.63	GO:0035329	hippo signaling
0.63	GO:0003157	endocardium development
0.63	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.63	GO:0060215	primitive hemopoiesis
0.63	GO:0006468	protein phosphorylation
0.62	GO:0046621	negative regulation of organ growth
0.61	GO:0045600	positive regulation of fat cell differentiation
0.61	GO:0032092	positive regulation of protein binding

0.67	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0042802	identical protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0000287	magnesium ion binding
0.46	GO:0008134	transcription factor binding
0.45	GO:0046983	protein dimerization activity
0.36	GO:0043539	protein serine/threonine kinase activator activity

0.48	GO:0016604	nuclear body
0.47	GO:0043234	protein complex
0.45	GO:0005829	cytosol

0.67

GO:0004674

sp|O54753|H17B6_RAT
17-beta-hydroxysteroid dehydrogenase type 6
Search

0.94	Retinol dehydrogenase similar protein 2

0.50	GO:0055114	oxidation-reduction process
0.47	GO:0001523	retinoid metabolic process
0.43	GO:0034754	cellular hormone metabolic process
0.42	GO:0008202	steroid metabolic process
0.42	GO:0016102	diterpenoid biosynthetic process
0.38	GO:0034308	primary alcohol metabolic process
0.37	GO:0072330	monocarboxylic acid biosynthetic process
0.36	GO:0035118	embryonic pectoral fin morphogenesis
0.36	GO:0031017	exocrine pancreas development
0.36	GO:0031018	endocrine pancreas development

0.58	GO:0004745	retinol dehydrogenase activity
0.43	GO:0016229	steroid dehydrogenase activity
0.36	GO:0042803	protein homodimerization activity
0.34	GO:0009055	electron transfer activity

0.40	GO:0005783	endoplasmic reticulum
0.39	GO:0005730	nucleolus
0.38	GO:0005829	cytosol
0.37	GO:0031090	organelle membrane
0.36	GO:0005769	early endosome
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0044440	endosomal part
0.36	GO:0031984	organelle subcompartment
0.35	GO:0098805	whole membrane
0.30	GO:0031224	intrinsic component of membrane

0.58

EC:1.1.1.105

GO:0004745

sp|O54766|ZP1_RAT
Zona pellucida sperm-binding protein 1
Search

ZP1

0.92	Egg envelope component ZPB

0.53	GO:0007338	single fertilization
0.52	GO:2000360	negative regulation of binding of sperm to zona pellucida
0.51	GO:2000344	positive regulation of acrosome reaction
0.50	GO:0002922	positive regulation of humoral immune response
0.49	GO:0042102	positive regulation of T cell proliferation
0.48	GO:0017156	calcium ion regulated exocytosis
0.39	GO:0009988	cell-cell recognition

0.52	GO:0032190	acrosin binding
0.45	GO:0042802	identical protein binding

0.62	GO:0005576	extracellular region
0.38	GO:0005886	plasma membrane
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|O54767|ZP2_RAT
Zona pellucida sperm-binding protein 2
Search

ZP2

0.97	Zona pellucida protein subunit A

0.71	GO:0060468	prevention of polyspermy
0.67	GO:0007339	binding of sperm to zona pellucida
0.42	GO:0060046	regulation of acrosome reaction
0.37	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.34	GO:0007165	signal transduction

0.69	GO:0032190	acrosin binding
0.57	GO:0042802	identical protein binding
0.37	GO:0015026	coreceptor activity

0.67	GO:0005771	multivesicular body
0.60	GO:0005576	extracellular region
0.56	GO:0005783	endoplasmic reticulum
0.47	GO:0005886	plasma membrane
0.37	GO:0016234	inclusion body
0.35	GO:0042597	periplasmic space
0.30	GO:0044425	membrane part

sp|O54769|FGF16_RAT
Fibroblast growth factor 16
Search

FGF16

0.62	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.59	GO:0090287	regulation of cellular response to growth factor stimulus
0.57	GO:2001028	positive regulation of endothelial cell chemotaxis
0.53	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.53	GO:0035107	appendage morphogenesis
0.52	GO:0048513	animal organ development
0.52	GO:0032927	positive regulation of activin receptor signaling pathway
0.52	GO:0046546	development of primary male sexual characteristics
0.51	GO:0048505	regulation of timing of cell differentiation

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.39	GO:0008201	heparin binding
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|O54772|SMRD2_RAT
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
Search

SMARCD2

0.97	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

0.79	GO:0043044	ATP-dependent chromatin remodeling
0.54	GO:0031498	chromatin disassembly
0.54	GO:0032986	protein-DNA complex disassembly
0.50	GO:0034728	nucleosome organization
0.45	GO:0030223	neutrophil differentiation
0.44	GO:0002244	hematopoietic progenitor cell differentiation
0.38	GO:0016569	covalent chromatin modification
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.37	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0031492	nucleosomal DNA binding
0.37	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0003713	transcription coactivator activity
0.33	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0016514	SWI/SNF complex
0.48	GO:0005654	nucleoplasm
0.46	GO:0071565	nBAF complex
0.46	GO:0071564	npBAF complex
0.34	GO:0043234	protein complex
0.33	GO:0048475	coated membrane
0.32	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

sp|O54783|CHKB_RAT
Choline/ethanolamine kinase
Search

CHKB

0.66	Choline kinase alpha

0.61	GO:0006657	CDP-choline pathway
0.57	GO:0016310	phosphorylation
0.53	GO:0006646	phosphatidylethanolamine biosynthetic process
0.46	GO:0007517	muscle organ development
0.38	GO:1904681	response to 3-methylcholanthrene
0.36	GO:0006580	ethanolamine metabolic process
0.36	GO:0019695	choline metabolic process
0.35	GO:0009636	response to toxic substance
0.33	GO:0006869	lipid transport
0.32	GO:0007165	signal transduction

0.62	GO:0004103	choline kinase activity
0.59	GO:0004305	ethanolamine kinase activity
0.51	GO:0004104	cholinesterase activity
0.47	GO:0042803	protein homodimerization activity
0.41	GO:0008144	drug binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0033265	choline binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004871	signal transducer activity

0.36

GO:0005829

cytosol

0.62	EC:2.7.1.32	GO:0004103
0.62	KEGG:R01021	GO:0004103

sp|O54800|CADH8_RAT
Cadherin-8
Search

CDH8

0.92	Cadherin-8 isoform B

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.51	GO:0035249	synaptic transmission, glutamatergic
0.48	GO:0009409	response to cold
0.35	GO:0034332	adherens junction organization
0.35	GO:0021957	corticospinal tract morphogenesis
0.35	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.46	GO:0042802	identical protein binding

0.55	GO:0005886	plasma membrane
0.51	GO:0043083	synaptic cleft
0.50	GO:0043679	axon terminus
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|O54814|CCR3_RAT
C-C chemokine receptor type 3
Search

CCR3

0.97	C-C motif chemokine receptor 3

0.82	GO:0070098	chemokine-mediated signaling pathway
0.79	GO:0006954	inflammatory response
0.70	GO:0006935	chemotaxis
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0090026	positive regulation of monocyte chemotaxis
0.65	GO:0006955	immune response
0.57	GO:0051094	positive regulation of developmental process
0.57	GO:0051240	positive regulation of multicellular organismal process
0.56	GO:2000026	regulation of multicellular organismal development
0.53	GO:0001938	positive regulation of endothelial cell proliferation

0.85	GO:0016493	C-C chemokine receptor activity
0.66	GO:0019957	C-C chemokine binding
0.46	GO:0004435	phosphatidylinositol phospholipase C activity
0.44	GO:0031727	CCR2 chemokine receptor binding
0.37	GO:0003779	actin binding
0.33	GO:0042803	protein homodimerization activity

0.51	GO:0009897	external side of plasma membrane
0.39	GO:0005768	endosome
0.36	GO:0043025	neuronal cell body
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0005615	extracellular space
0.34	GO:0030425	dendrite
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol

0.46	EC:3.1.4.11	GO:0004435
0.46	KEGG:R03435	GO:0004435

sp|O54835|SMAD9_RAT
Mothers against decapentaplegic homolog 9
Search

SMAD9

0.59	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.54	GO:0030901	midbrain development
0.54	GO:0060395	SMAD protein signal transduction
0.54	GO:0001657	ureteric bud development
0.53	GO:0071773	cellular response to BMP stimulus
0.53	GO:0030902	hindbrain development

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.46	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part

sp|O54838|DUS5_RAT
Dual specificity protein phosphatase 5
Search

DUSP5

0.71	Dual specificity protein phosphatase

0.85	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.59	GO:0035970	peptidyl-threonine dephosphorylation
0.50	GO:0001706	endoderm formation
0.41	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.38	GO:0042981	regulation of apoptotic process
0.36	GO:0045906	negative regulation of vasoconstriction
0.36	GO:0071850	mitotic cell cycle arrest
0.36	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.36	GO:0051447	negative regulation of meiotic cell cycle

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.43	GO:0008330	protein tyrosine/threonine phosphatase activity
0.43	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.34	GO:0005515	protein binding
0.33	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.32	GO:0012505	endomembrane system
0.32	GO:0031090	organelle membrane
0.32	GO:0031975	envelope
0.30	GO:0016021	integral component of membrane

0.85

GO:0017017

sp|O54842|NUPR1_RAT
Nuclear protein 1
Search

NUPR1

0.96	Nuclear protein 1, transcriptional regulator

0.79	GO:2000194	regulation of female gonad development
0.78	GO:0048147	negative regulation of fibroblast proliferation
0.77	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.76	GO:0002526	acute inflammatory response
0.76	GO:0035914	skeletal muscle cell differentiation
0.74	GO:0008584	male gonad development
0.70	GO:0045786	negative regulation of cell cycle
0.70	GO:0008283	cell proliferation
0.69	GO:0043065	positive regulation of apoptotic process
0.68	GO:0006473	protein acetylation

0.71	GO:0003682	chromatin binding
0.51	GO:0003677	DNA binding
0.36	GO:0005515	protein binding

0.63	GO:0032993	protein-DNA complex
0.60	GO:0005829	cytosol
0.59	GO:0005634	nucleus

sp|O54852|KCNH7_RAT
Potassium voltage-gated channel subfamily H member 7
Search

KCNH7

0.93	Potassium voltage-gated channel subfamily H member 7

0.75	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.46	GO:0042391	regulation of membrane potential
0.42	GO:0023014	signal transduction by protein phosphorylation
0.41	GO:0000160	phosphorelay signal transduction system
0.36	GO:0051291	protein heterooligomerization
0.35	GO:0007623	circadian rhythm

0.77	GO:0005249	voltage-gated potassium channel activity
0.42	GO:0000155	phosphorelay sensor kinase activity
0.35	GO:0099094	ligand-gated cation channel activity

0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0005622	intracellular

0.42

GO:0000155

sp|O54853|KCNH6_RAT
Potassium voltage-gated channel subfamily H member 6
Search

KCNH6

0.85	Potassium voltage-gated channel subfamily H member 6

0.76	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.52	GO:0086091	regulation of heart rate by cardiac conduction
0.49	GO:0042391	regulation of membrane potential
0.40	GO:0060047	heart contraction
0.39	GO:0043267	negative regulation of potassium ion transport
0.39	GO:0051291	protein heterooligomerization
0.39	GO:0070252	actin-mediated cell contraction
0.38	GO:0043268	positive regulation of potassium ion transport
0.38	GO:0006941	striated muscle contraction

0.78	GO:0005249	voltage-gated potassium channel activity
0.41	GO:0099094	ligand-gated cation channel activity
0.40	GO:0055131	C3HC4-type RING finger domain binding
0.39	GO:0097110	scaffold protein binding
0.38	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0000155	phosphorelay sensor kinase activity
0.34	GO:0008237	metallopeptidase activity

0.44	GO:0005887	integral component of plasma membrane
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0034705	potassium channel complex
0.37	GO:0009986	cell surface

0.35

GO:0000155

tr|O54854|O54854_RAT
Kallikrein 6, isoform CRA_a
Search

0.94	Brain serine protease

0.61	GO:0006508	proteolysis
0.56	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.53	GO:0070997	neuron death
0.47	GO:1903035	negative regulation of response to wounding
0.46	GO:0032102	negative regulation of response to external stimulus
0.46	GO:0051239	regulation of multicellular organismal process
0.46	GO:0009611	response to wounding
0.46	GO:0032501	multicellular organismal process
0.44	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.44	GO:0048856	anatomical structure development

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:1904854	proteasome core complex binding
0.38	GO:1990405	protein antigen binding
0.37	GO:0034185	apolipoprotein binding
0.37	GO:0019900	kinase binding
0.36	GO:0051087	chaperone binding
0.36	GO:0019904	protein domain specific binding
0.35	GO:0005102	receptor binding
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0016301	kinase activity

0.50	GO:0005576	extracellular region
0.44	GO:0097180	serine protease inhibitor complex
0.43	GO:0030141	secretory granule
0.37	GO:0031232	extrinsic component of external side of plasma membrane
0.34	GO:0044218	other organism cell membrane
0.34	GO:0005730	nucleolus
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0060205	cytoplasmic vesicle lumen
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|O54857|O54857_RAT
Phosphatase and tensin homolog
Search

PTEN

0.85	Phosphatase and tensin homolog A

0.86	GO:0051895	negative regulation of focal adhesion assembly
0.85	GO:0051898	negative regulation of protein kinase B signaling
0.83	GO:0030336	negative regulation of cell migration
0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.80	GO:0046855	inositol phosphate dephosphorylation
0.79	GO:0008285	negative regulation of cell proliferation
0.79	GO:0031647	regulation of protein stability
0.78	GO:2000808	negative regulation of synaptic vesicle clustering
0.77	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.76	GO:1903689	regulation of wound healing, spreading of epidermal cells

0.87	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
0.87	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
0.85	GO:0030165	PDZ domain binding
0.79	GO:0051717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.74	GO:1990381	ubiquitin-specific protease binding
0.73	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.70	GO:0010997	anaphase-promoting complex binding
0.65	GO:0019901	protein kinase binding

0.75	GO:0035749	myelin sheath adaxonal region
0.74	GO:0043220	Schmidt-Lanterman incisure
0.68	GO:0016324	apical plasma membrane
0.65	GO:0043005	neuron projection
0.64	GO:0009898	cytoplasmic side of plasma membrane
0.60	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol
0.38	GO:0036477	somatodendritic compartment
0.38	GO:0045211	postsynaptic membrane
0.38	GO:0120038	plasma membrane bounded cell projection part

0.87

EC:3.1.3.67

GO:0016314

sp|O54858|CBPZ_RAT
Carboxypeptidase Z
Search

CPZ

0.97	Carboxypeptidase Z

0.60	GO:0006508	proteolysis
0.43	GO:0051604	protein maturation
0.39	GO:0006518	peptide metabolic process
0.39	GO:0016055	Wnt signaling pathway
0.34	GO:0007275	multicellular organism development

0.77	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding
0.44	GO:0004185	serine-type carboxypeptidase activity

0.43	GO:0005615	extracellular space
0.39	GO:0005578	proteinaceous extracellular matrix
0.37	GO:1903561	extracellular vesicle

0.77

EC:3.4.17

GO:0004181

sp|O54861|SORT_RAT
Sortilin
Search

SORT1

0.78

Sortilin

0.59	GO:0051005	negative regulation of lipoprotein lipase activity
0.59	GO:0038180	nerve growth factor signaling pathway
0.58	GO:0048227	plasma membrane to endosome transport
0.57	GO:0048011	neurotrophin TRK receptor signaling pathway
0.57	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.56	GO:0045599	negative regulation of fat cell differentiation
0.56	GO:0046323	glucose import
0.56	GO:0008333	endosome to lysosome transport
0.55	GO:0006895	Golgi to endosome transport
0.55	GO:0014902	myotube differentiation

0.60	GO:0030379	neurotensin receptor activity, non-G-protein coupled
0.60	GO:0010465	nerve growth factor receptor activity
0.59	GO:0048406	nerve growth factor binding
0.49	GO:0019899	enzyme binding
0.36	GO:0016492	G-protein coupled neurotensin receptor activity
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0004175	endopeptidase activity

0.69	GO:0005794	Golgi apparatus
0.54	GO:0030140	trans-Golgi network transport vesicle
0.53	GO:0005905	clathrin-coated pit
0.53	GO:0005769	early endosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0030659	cytoplasmic vesicle membrane
0.51	GO:0009986	cell surface
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.39	GO:0005765	lysosomal membrane

sp|O54874|MRCKA_RAT
Serine/threonine-protein kinase MRCK alpha
Search

CDC42BPA

0.82	Serine/threonine-protein kinase MRCK alpha

0.73	GO:0030036	actin cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.43	GO:0016477	cell migration
0.40	GO:0007097	nuclear migration
0.38	GO:0000226	microtubule cytoskeleton organization
0.36	GO:0051056	regulation of small GTPase mediated signal transduction

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.42	GO:0042802	identical protein binding

0.45	GO:0042641	actomyosin
0.41	GO:0030027	lamellipodium
0.39	GO:0070062	extracellular exosome
0.38	GO:0005911	cell-cell junction
0.34	GO:0005737	cytoplasm

0.70

GO:0004674

sp|O54880|RPH3L_RAT
Rab effector Noc2
Search

RPH3AL

0.97	LOW QUALITY PROTEIN: rab effector Noc2

0.77	GO:0017157	regulation of exocytosis
0.69	GO:0006886	intracellular protein transport
0.55	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.52	GO:0042593	glucose homeostasis
0.45	GO:0006887	exocytosis
0.43	GO:0050714	positive regulation of protein secretion
0.42	GO:0048489	synaptic vesicle transport
0.42	GO:0099504	synaptic vesicle cycle
0.42	GO:0099643	signal release from synapse
0.42	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.81	GO:0017137	Rab GTPase binding
0.53	GO:0046872	metal ion binding
0.50	GO:0005544	calcium-dependent phospholipid binding
0.41	GO:0030274	LIM domain binding
0.39	GO:0019905	syntaxin binding
0.38	GO:0030276	clathrin binding
0.34	GO:0008092	cytoskeletal protein binding

0.45	GO:0005622	intracellular
0.42	GO:0098793	presynapse
0.42	GO:0031982	vesicle
0.40	GO:0012505	endomembrane system
0.39	GO:0005886	plasma membrane
0.39	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle

sp|O54888|RPA2_RAT
DNA-directed RNA polymerase I subunit RPA2
Search

POLR1B

0.41	DNA-directed RNA polymerase subunit beta

0.58	GO:0017126	nucleologenesis
0.57	GO:0006351	transcription, DNA-templated
0.55	GO:0007566	embryo implantation
0.47	GO:0016072	rRNA metabolic process
0.36	GO:0040029	regulation of gene expression, epigenetic
0.35	GO:0016458	gene silencing
0.34	GO:0006325	chromatin organization
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0010628	positive regulation of gene expression

0.69	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.64	GO:0001882	nucleoside binding
0.54	GO:0003677	DNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.52	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0031974	membrane-enclosed lumen
0.48	GO:0005829	cytosol
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part

0.69

EC:2.7.7.6

GO:0003899

sp|O54889|RPA1_RAT
DNA-directed RNA polymerase I subunit RPA1
Search

POLR1A

0.49	DNA-directed RNA polymerase subunit

0.65	GO:1904750	negative regulation of protein localization to nucleolus
0.59	GO:0006360	transcription by RNA polymerase I
0.44	GO:0048703	embryonic viscerocranium morphogenesis
0.43	GO:0014032	neural crest cell development
0.37	GO:0040029	regulation of gene expression, epigenetic
0.36	GO:0009303	rRNA transcription
0.35	GO:0016458	gene silencing
0.35	GO:0006354	DNA-templated transcription, elongation
0.34	GO:0006353	DNA-templated transcription, termination
0.34	GO:0006325	chromatin organization

0.69	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0003682	chromatin binding
0.54	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0008373	sialyltransferase activity

0.60	GO:0005634	nucleus
0.54	GO:0000428	DNA-directed RNA polymerase complex
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.45	GO:0044446	intracellular organelle part

0.69

EC:2.7.7.6

GO:0003899

sp|O54898|CAC1G_RAT
Voltage-dependent T-type calcium channel subunit alpha-1G
Search

CACNA1G

0.85	Voltage-dependent T-type calcium channel subunit alpha

0.84	GO:0070509	calcium ion import
0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0034765	regulation of ion transmembrane transport
0.57	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.56	GO:0086046	membrane depolarization during SA node cell action potential
0.56	GO:0086045	membrane depolarization during AV node cell action potential
0.54	GO:0086002	cardiac muscle cell action potential involved in contraction
0.54	GO:0086091	regulation of heart rate by cardiac conduction
0.54	GO:0010045	response to nickel cation
0.51	GO:0007268	chemical synaptic transmission

0.86	GO:0008332	low voltage-gated calcium channel activity
0.57	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential
0.57	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential
0.56	GO:0097110	scaffold protein binding
0.44	GO:0005248	voltage-gated sodium channel activity
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.80	GO:0005891	voltage-gated calcium channel complex
0.39	GO:0005737	cytoplasm
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite

sp|O54902|NRAM2_RAT
Natural resistance-associated macrophage protein 2
Search

SLC11A2

0.87	Natural resistance-associated macrophage protein 2

0.66	GO:0030001	metal ion transport
0.49	GO:0060586	multicellular organismal iron ion homeostasis
0.48	GO:0048821	erythrocyte development
0.47	GO:0010039	response to iron ion
0.47	GO:0048813	dendrite morphogenesis
0.46	GO:0007611	learning or memory
0.43	GO:0072511	divalent inorganic cation transport
0.43	GO:0006783	heme biosynthetic process
0.42	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.40	GO:1902600	hydrogen ion transmembrane transport

0.69	GO:0046873	metal ion transmembrane transporter activity
0.51	GO:0015094	lead ion transmembrane transporter activity
0.49	GO:0046870	cadmium ion binding
0.45	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.45	GO:0015295	solute:proton symporter activity
0.42	GO:0070835	chromium ion transmembrane transporter activity
0.36	GO:0050897	cobalt ion binding
0.36	GO:0016151	nickel cation binding
0.36	GO:0030145	manganese ion binding
0.35	GO:0005507	copper ion binding

0.50	GO:0070826	paraferritin complex
0.48	GO:0031526	brush border membrane
0.47	GO:0045178	basal part of cell
0.47	GO:0031902	late endosome membrane
0.47	GO:0055037	recycling endosome
0.46	GO:0005765	lysosomal membrane
0.46	GO:0016324	apical plasma membrane
0.46	GO:1903561	extracellular vesicle
0.46	GO:0005769	early endosome
0.45	GO:0048471	perinuclear region of cytoplasm

sp|O54912|KCNK3_RAT
Potassium channel subfamily K member 3
Search

KCNK3

0.93	Potassium two pore domain channel subfamily K member 3

0.71	GO:0071805	potassium ion transmembrane transport
0.64	GO:0010469	regulation of receptor activity
0.54	GO:0030322	stabilization of membrane potential
0.48	GO:0060047	heart contraction
0.41	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.41	GO:0071294	cellular response to zinc ion
0.40	GO:0090102	cochlea development
0.40	GO:0071456	cellular response to hypoxia
0.39	GO:0007420	brain development
0.37	GO:0042493	response to drug

0.78	GO:0005252	open rectifier potassium channel activity
0.67	GO:0008083	growth factor activity
0.59	GO:0022841	potassium ion leak channel activity
0.53	GO:0044548	S100 protein binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.39	GO:0008022	protein C-terminus binding

0.63	GO:0005615	extracellular space
0.45	GO:0005887	integral component of plasma membrane
0.38	GO:0008021	synaptic vesicle

sp|O54921|EXOC2_RAT
Exocyst complex component 2
Search

EXOC2

0.93	Exocyst complex component 2

0.82	GO:0006893	Golgi to plasma membrane transport
0.59	GO:2000535	regulation of entry of bacterium into host cell
0.51	GO:0001927	exocyst assembly
0.36	GO:0015031	protein transport
0.35	GO:0045921	positive regulation of exocytosis

0.58	GO:0017160	Ral GTPase binding
0.56	GO:0047485	protein N-terminus binding
0.53	GO:0019901	protein kinase binding
0.36	GO:0030742	GTP-dependent protein binding

0.77	GO:0000145	exocyst
0.40	GO:0090543	Flemming body
0.37	GO:0097544	ciliary shaft
0.36	GO:0097546	ciliary base
0.35	GO:0097731	9+0 non-motile cilium
0.34	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane

sp|O54922|EXOC7_RAT
Exocyst complex component 7
Search

EXOC7

0.72	Exocyst complex component 7

0.77	GO:0006887	exocytosis
0.48	GO:2000535	regulation of entry of bacterium into host cell
0.36	GO:0015031	protein transport

0.33

GO:0005515

protein binding

0.79	GO:0000145	exocyst
0.48	GO:0032584	growth cone membrane
0.47	GO:0034451	centriolar satellite
0.39	GO:0090543	Flemming body
0.38	GO:0097546	ciliary base
0.38	GO:0097731	9+0 non-motile cilium
0.36	GO:0005829	cytosol

sp|O54923|EXOC6_RAT
Exocyst complex component 6
Search

EXOC6

0.76	Exocyst complex component

0.79	GO:0006904	vesicle docking involved in exocytosis
0.37	GO:0030218	erythrocyte differentiation
0.36	GO:0015031	protein transport
0.34	GO:0055114	oxidation-reduction process

0.37	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.36	GO:0020037	heme binding
0.36	GO:0005506	iron ion binding
0.34	GO:0005515	protein binding

0.77	GO:0000145	exocyst
0.40	GO:0090543	Flemming body
0.39	GO:0030426	growth cone
0.38	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016705

sp|O54924|EXOC8_RAT
Exocyst complex component 8
Search

EXOC8

0.96	Exocyst complex component 8

0.76	GO:0006887	exocytosis
0.60	GO:0022617	extracellular matrix disassembly
0.58	GO:0007032	endosome organization
0.52	GO:0051601	exocyst localization
0.48	GO:0048278	vesicle docking
0.45	GO:0043623	cellular protein complex assembly
0.39	GO:0015031	protein transport
0.36	GO:0016241	regulation of macroautophagy
0.32	GO:0055114	oxidation-reduction process

0.60	GO:0017160	Ral GTPase binding
0.35	GO:0035091	phosphatidylinositol binding
0.35	GO:0031418	L-ascorbic acid binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0005506	iron ion binding

0.78	GO:0000145	exocyst
0.56	GO:0005770	late endosome
0.50	GO:0005829	cytosol
0.44	GO:0030426	growth cone
0.42	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0031252	cell leading edge
0.36	GO:0097546	ciliary base
0.36	GO:0097731	9+0 non-motile cilium
0.34	GO:0005886	plasma membrane

0.34

GO:0016705

sp|O54937|PDK4_RAT
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
Search

PDK4

0.97	Pyruvate dehydrogenase kinase isozyme 4

0.72	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.67	GO:0008286	insulin receptor signaling pathway
0.65	GO:0010906	regulation of glucose metabolic process
0.63	GO:0042593	glucose homeostasis
0.63	GO:2000811	negative regulation of anoikis
0.62	GO:0071398	cellular response to fatty acid
0.62	GO:0046320	regulation of fatty acid oxidation
0.62	GO:0045124	regulation of bone resorption
0.62	GO:0006885	regulation of pH
0.61	GO:0031669	cellular response to nutrient levels

0.59	GO:0016301	kinase activity
0.51	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.48	GO:0140096	catalytic activity, acting on a protein
0.46	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0042803	protein homodimerization activity
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032403	protein complex binding
0.34	GO:0046982	protein heterodimerization activity

0.51	GO:0044429	mitochondrial part
0.48	GO:0045254	pyruvate dehydrogenase complex
0.47	GO:0019866	organelle inner membrane
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0005829	cytosol
0.43	GO:0044428	nuclear part

0.51

GO:0016773

sp|O54939|DHB3_RAT
Testosterone 17-beta-dehydrogenase 3
Search

HSD17B3

0.71	Very-long-chain 3-oxoacyl-CoA reductase

0.78	GO:0061370	testosterone biosynthetic process
0.75	GO:0030539	male genitalia development
0.51	GO:0055114	oxidation-reduction process
0.43	GO:0010811	positive regulation of cell-substrate adhesion
0.42	GO:0030198	extracellular matrix organization
0.41	GO:0006702	androgen biosynthetic process
0.38	GO:0018879	biphenyl metabolic process
0.38	GO:0017143	insecticide metabolic process
0.38	GO:0033591	response to L-ascorbic acid
0.38	GO:0033197	response to vitamin E

0.78	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity
0.44	GO:0001968	fibronectin binding
0.42	GO:0005518	collagen binding
0.42	GO:0008201	heparin binding
0.40	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.40	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.38	GO:0102341	3-oxo-lignoceroyl-CoA reductase activity
0.38	GO:0102340	3-oxo-behenoyl-CoA reductase activity
0.38	GO:0102342	3-oxo-cerotoyl-CoA reductase activity
0.38	GO:0102339	3-oxo-arachidoyl-CoA reductase activity

0.51	GO:0005783	endoplasmic reticulum
0.41	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.78	EC:1.1.1.64	GO:0047045
0.78	KEGG:R01838	GO:0047045

sp|O54947|HAVR1_RAT
Hepatitis A virus cellular receptor 1 homolog
Search

HAVCR1

0.85	T-cell immunoglobulin and mucin domain-containing protein 2

0.47	GO:0033005	positive regulation of mast cell activation
0.46	GO:0006508	proteolysis
0.43	GO:0010046	response to mycotoxin
0.43	GO:0033574	response to testosterone
0.42	GO:0006911	phagocytosis, engulfment
0.41	GO:0007584	response to nutrient
0.40	GO:0097286	iron ion import
0.39	GO:0046677	response to antibiotic
0.39	GO:0042493	response to drug
0.38	GO:0051806	entry into cell of other organism involved in symbiotic interaction

0.51	GO:0004252	serine-type endopeptidase activity
0.46	GO:0001786	phosphatidylserine binding
0.43	GO:0104005	hijacked molecular function
0.41	GO:0070287	ferritin receptor activity
0.36	GO:0005515	protein binding

0.45	GO:0009986	cell surface
0.43	GO:0005576	extracellular region
0.41	GO:0045335	phagocytic vesicle
0.41	GO:0016324	apical plasma membrane
0.41	GO:0031514	motile cilium
0.36	GO:0005887	integral component of plasma membrane

0.51

GO:0004252

sp|O54952|BRCA1_RAT
Breast cancer type 1 susceptibility protein homolog
Search

BRCA1

0.84	Breast cancer type 1 susceptibility protein homolog

0.74	GO:0085020	protein K6-linked ubiquitination
0.70	GO:0051865	protein autoubiquitination
0.65	GO:0006281	DNA repair
0.57	GO:0007049	cell cycle
0.56	GO:0006310	DNA recombination
0.55	GO:0070512	positive regulation of histone H4-K20 methylation
0.54	GO:0009048	dosage compensation by inactivation of X chromosome
0.54	GO:2000620	positive regulation of histone H4-K16 acetylation
0.53	GO:0071681	cellular response to indole-3-methanol
0.53	GO:0051572	negative regulation of histone H3-K4 methylation

0.74	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.53	GO:0001105	RNA polymerase II transcription coactivator activity
0.50	GO:0070063	RNA polymerase binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0003723	RNA binding
0.39	GO:0003682	chromatin binding
0.35	GO:0015631	tubulin binding

0.73	GO:0031436	BRCA1-BARD1 complex
0.57	GO:0005694	chromosome
0.52	GO:0070531	BRCA1-A complex
0.44	GO:0031981	nuclear lumen
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0005886	plasma membrane
0.39	GO:0005815	microtubule organizing center
0.39	GO:0005759	mitochondrial matrix

0.74

GO:0004842

sp|O54960|CAPON_RAT
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Search

NOS1AP

0.95	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 3

0.86	GO:0003062	regulation of heart rate by chemical signal
0.84	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.53	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
0.52	GO:1901841	regulation of high voltage-gated calcium channel activity
0.51	GO:0098901	regulation of cardiac muscle cell action potential
0.51	GO:0050999	regulation of nitric-oxide synthase activity
0.51	GO:0045428	regulation of nitric oxide biosynthetic process
0.50	GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation
0.49	GO:0010750	positive regulation of nitric oxide mediated signal transduction
0.49	GO:1903116	positive regulation of actin filament-based movement

0.84	GO:0050998	nitric-oxide synthase binding
0.42	GO:0030165	PDZ domain binding
0.42	GO:0002020	protease binding
0.40	GO:0004672	protein kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003676	nucleic acid binding

0.81	GO:0030315	T-tubule
0.80	GO:0033017	sarcoplasmic reticulum membrane
0.78	GO:0005901	caveola
0.78	GO:0030018	Z disc
0.57	GO:0005739	mitochondrion
0.49	GO:1902937	inward rectifier potassium channel complex
0.46	GO:0005891	voltage-gated calcium channel complex
0.45	GO:0031965	nuclear membrane
0.44	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005829	cytosol

sp|O54963|REST_RAT
RE1-silencing transcription factor
Search

REST

0.78	Neural-restrictive silencer factor

0.84	GO:0045665	negative regulation of neuron differentiation
0.79	GO:0043065	positive regulation of apoptotic process
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.60	GO:2000797	regulation of amniotic stem cell differentiation
0.60	GO:2000740	negative regulation of mesenchymal stem cell differentiation
0.59	GO:0032345	negative regulation of aldosterone metabolic process
0.59	GO:2000065	negative regulation of cortisol biosynthetic process
0.58	GO:0032347	regulation of aldosterone biosynthetic process
0.58	GO:0071257	cellular response to electrical stimulus
0.58	GO:0043922	negative regulation by host of viral transcription

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.57	GO:0015271	outward rectifier potassium channel activity
0.54	GO:0001046	core promoter sequence-specific DNA binding
0.49	GO:0008134	transcription factor binding
0.49	GO:0003682	chromatin binding
0.38	GO:0032403	protein complex binding
0.37	GO:0046872	metal ion binding
0.33	GO:0004407	histone deacetylase activity

0.61	GO:0005634	nucleus
0.53	GO:0017053	transcriptional repressor complex
0.45	GO:0005829	cytosol
0.38	GO:0000785	chromatin
0.36	GO:0043234	protein complex
0.32	GO:0070013	intracellular organelle lumen

0.33

EC:3.5.1.98

GO:0004407

sp|O54968|NF2L2_RAT
Nuclear factor erythroid 2-related factor 2
Search

NFE2L2

0.97	Nuclear factor, erythroid 2 like 2

0.75	GO:0034599	cellular response to oxidative stress
0.59	GO:1903786	regulation of glutathione biosynthetic process
0.58	GO:0071499	cellular response to laminar fluid shear stress
0.58	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.58	GO:0036499	PERK-mediated unfolded protein response
0.57	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.57	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.57	GO:1901032	negative regulation of response to reactive oxygen species
0.57	GO:2001039	negative regulation of cellular response to drug
0.56	GO:1903205	regulation of hydrogen peroxide-induced cell death

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0019904	protein domain specific binding
0.40	GO:0001221	transcription cofactor binding
0.39	GO:0046982	protein heterodimerization activity
0.35	GO:0120013	intermembrane lipid transfer activity

0.61	GO:0005634	nucleus
0.52	GO:0005813	centrosome
0.49	GO:0005794	Golgi apparatus
0.48	GO:0000785	chromatin
0.48	GO:0005829	cytosol
0.48	GO:0032993	protein-DNA complex
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0005886	plasma membrane
0.38	GO:0005667	transcription factor complex

sp|O54975|XPP1_RAT
Xaa-Pro aminopeptidase 1
Search

XPNPEP1

0.87	X-prolyl aminopeptidase

0.60	GO:0006508	proteolysis
0.59	GO:0010815	bradykinin catabolic process

0.76	GO:0070006	metalloaminopeptidase activity
0.53	GO:0046872	metal ion binding
0.51	GO:0042803	protein homodimerization activity

0.48	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome

sp|O54980|SNG2_RAT
Synaptogyrin-2
Search

SYNGR2

0.87	Synaptogyrin

0.46	GO:0045055	regulated exocytosis
0.43	GO:0032411	positive regulation of transporter activity
0.42	GO:0048499	synaptic vesicle membrane organization
0.40	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.39	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.39	GO:0071310	cellular response to organic substance
0.39	GO:1990823	response to leukemia inhibitory factor
0.37	GO:0060976	coronary vasculature development
0.37	GO:0035904	aorta development
0.37	GO:0000185	activation of MAPKKK activity

0.44	GO:0042169	SH2 domain binding
0.43	GO:0047485	protein N-terminus binding
0.37	GO:0004722	protein serine/threonine phosphatase activity
0.37	GO:0019209	kinase activator activity
0.34	GO:0016972	thiol oxidase activity
0.32	GO:0016301	kinase activity

0.59	GO:0008021	synaptic vesicle
0.52	GO:0031594	neuromuscular junction
0.50	GO:0099501	exocytic vesicle membrane
0.40	GO:0030054	cell junction
0.37	GO:0070062	extracellular exosome
0.37	GO:0016607	nuclear speck
0.35	GO:0005829	cytosol
0.35	GO:0005811	lipid droplet
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.8.3.2

GO:0016972

sp|O55000|PP1RA_RAT
Serine/threonine-protein phosphatase 1 regulatory subunit 10
Search

PPP1R10

0.95	Phosphatase 1 nuclear targeting subunit

0.48	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.37	GO:0006606	protein import into nucleus

0.52	GO:0046872	metal ion binding
0.48	GO:0004864	protein phosphatase inhibitor activity
0.40	GO:0003723	RNA binding
0.38	GO:0003677	DNA binding
0.38	GO:0008157	protein phosphatase 1 binding

0.68	GO:0072357	PTW/PP1 phosphatase complex
0.66	GO:0000784	nuclear chromosome, telomeric region
0.63	GO:0016604	nuclear body
0.59	GO:0000785	chromatin

sp|O55004|RNAS4_RAT
Ribonuclease 4
Search

RNASE4

0.94	Ribonuclease pancreatic

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0016070	RNA metabolic process
0.37	GO:0009267	cellular response to starvation
0.34	GO:0098542	defense response to other organism
0.34	GO:0009615	response to virus
0.34	GO:0002252	immune effector process
0.33	GO:0050691	regulation of defense response to virus by host
0.33	GO:0001525	angiogenesis
0.33	GO:0009617	response to bacterium
0.32	GO:0009966	regulation of signal transduction

0.65	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.47	GO:0004540	ribonuclease activity
0.34	GO:0005515	protein binding

0.51	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.33	GO:0046658	anchored component of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O55005|ROBO1_RAT
Roundabout homolog 1
Search

ROBO1

0.97	Roundabout guidance receptor 1

0.85	GO:0035385	Roundabout signaling pathway
0.81	GO:0007411	axon guidance
0.80	GO:0007507	heart development
0.57	GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration
0.57	GO:0050925	negative regulation of negative chemotaxis
0.56	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.56	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.56	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway
0.55	GO:0002042	cell migration involved in sprouting angiogenesis
0.54	GO:0035025	positive regulation of Rho protein signal transduction

0.55	GO:0030275	LRR domain binding
0.48	GO:0042802	identical protein binding
0.39	GO:0008046	axon guidance receptor activity

0.49	GO:0009986	cell surface
0.42	GO:0005886	plasma membrane
0.39	GO:0030424	axon
0.38	GO:0005737	cytoplasm
0.37	GO:0031252	cell leading edge
0.36	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

sp|O55006|ROB1_RAT
Protein RoBo-1
Search

0.77

GO:0046849

bone remodeling

0.60

GO:0005576

extracellular region

sp|O55007|RGPA1_RAT
Ral GTPase-activating protein subunit alpha-1
Search

RALGAPA1

0.90	Ral GTPase activating protein catalytic alpha subunit 1

0.76	GO:0043547	positive regulation of GTPase activity
0.74	GO:0051056	regulation of small GTPase mediated signal transduction
0.45	GO:0007420	brain development
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.33	GO:0006413	translational initiation

0.76	GO:0005096	GTPase activator activity
0.40	GO:0046982	protein heterodimerization activity
0.33	GO:0031369	translation initiation factor binding
0.33	GO:0003743	translation initiation factor activity

0.61	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.32	GO:0043234	protein complex

sp|O55012|PICAL_RAT
Phosphatidylinositol-binding clathrin assembly protein
Search

PICALM

0.86	Phosphatidylinositol-binding clathrin assembly protein isoform 3

0.82	GO:0048268	clathrin coat assembly
0.71	GO:0006897	endocytosis
0.57	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
0.57	GO:0097753	membrane bending
0.57	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
0.57	GO:1900223	positive regulation of amyloid-beta clearance
0.56	GO:1904684	negative regulation of metalloendopeptidase activity
0.56	GO:1902004	positive regulation of amyloid-beta formation
0.56	GO:0097494	regulation of vesicle size
0.56	GO:1905247	positive regulation of aspartic-type peptidase activity

0.84	GO:0005545	1-phosphatidylinositol binding
0.80	GO:0030276	clathrin binding
0.54	GO:0050750	low-density lipoprotein particle receptor binding
0.53	GO:0098748	endocytic adaptor activity
0.51	GO:0045296	cadherin binding
0.51	GO:0017137	Rab GTPase binding
0.38	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0017124	SH3 domain binding
0.35	GO:0042802	identical protein binding
0.34	GO:0003735	structural constituent of ribosome

0.79	GO:0030136	clathrin-coated vesicle
0.57	GO:0070381	endosome to plasma membrane transport vesicle
0.55	GO:0097418	neurofibrillary tangle
0.52	GO:0030666	endocytic vesicle membrane
0.52	GO:0005905	clathrin-coated pit
0.51	GO:0043025	neuronal cell body
0.51	GO:0005769	early endosome
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0030131	clathrin adaptor complex
0.50	GO:0030120	vesicle coat

sp|O55034|SPAG4_RAT
Sperm-associated antigen 4 protein
Search

SPAG4

0.95	SUN domain-containing protein 5

0.55	GO:0090286	cytoskeletal anchoring at nuclear membrane
0.55	GO:0006998	nuclear envelope organization
0.54	GO:0007283	spermatogenesis
0.42	GO:0030154	cell differentiation
0.41	GO:0090292	nuclear matrix anchoring at nuclear membrane
0.40	GO:0030473	nuclear migration along microtubule
0.40	GO:0021799	cerebral cortex radially oriented cell migration
0.40	GO:0051642	centrosome localization
0.39	GO:0070197	meiotic attachment of telomere to nuclear envelope
0.39	GO:0007129	synapsis

0.55	GO:0043495	protein membrane anchor
0.40	GO:0005521	lamin binding
0.36	GO:0042802	identical protein binding
0.34	GO:0005198	structural molecule activity

0.62	GO:0005637	nuclear inner membrane
0.58	GO:0106094	nuclear membrane microtubule tethering complex
0.58	GO:0034992	microtubule organizing center attachment site
0.57	GO:0044453	nuclear membrane part
0.54	GO:0031301	integral component of organelle membrane
0.48	GO:0097224	sperm connecting piece
0.39	GO:0002080	acrosomal membrane
0.38	GO:0005856	cytoskeleton
0.35	GO:0099512	supramolecular fiber
0.34	GO:0031981	nuclear lumen

sp|O55035|PPIG_RAT
Peptidyl-prolyl cis-trans isomerase G
Search

PPIG

0.95	Peptidyl-prolyl cis-trans isomerase G

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.67	GO:0006457	protein folding
0.36	GO:0008380	RNA splicing
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.38	GO:0016018	cyclosporin A binding
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity

0.59	GO:0016607	nuclear speck
0.52	GO:0005829	cytosol
0.42	GO:0016363	nuclear matrix
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:5.2.1.8

GO:0003755

sp|O55043|ARHG7_RAT
Rho guanine nucleotide exchange factor 7
Search

ARHGEF7

0.90	PAK-interacting exchange factor

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.61	GO:0035556	intracellular signal transduction
0.54	GO:0060124	positive regulation of growth hormone secretion
0.53	GO:0030032	lamellipodium assembly
0.51	GO:0002244	hematopoietic progenitor cell differentiation
0.51	GO:0007030	Golgi organization
0.50	GO:0043065	positive regulation of apoptotic process
0.41	GO:0071896	protein localization to adherens junction
0.41	GO:0055113	epiboly involved in gastrulation with mouth forming second

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.49	GO:0019901	protein kinase binding

0.51	GO:0043025	neuronal cell body
0.50	GO:0030027	lamellipodium
0.49	GO:0000322	storage vacuole
0.49	GO:0043005	neuron projection
0.45	GO:0005829	cytosol
0.42	GO:0043234	protein complex
0.40	GO:0005886	plasma membrane
0.38	GO:0001726	ruffle
0.37	GO:0005925	focal adhesion
0.37	GO:0005938	cell cortex

sp|O55081|RBL2_RAT
Retinoblastoma-like protein 2
Search

RBL2

0.97	RB transcriptional corepressor like 2

0.73	GO:0051726	regulation of cell cycle
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.67	GO:0007049	cell cycle
0.58	GO:0043550	regulation of lipid kinase activity
0.49	GO:0010629	negative regulation of gene expression
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0048522	positive regulation of cellular process
0.34	GO:0048523	negative regulation of cellular process

0.60	GO:1990841	promoter-specific chromatin binding
0.36	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|O55096|DPP3_RAT
Dipeptidyl peptidase 3
Search

DPP3

0.75	Dipeptidyl peptidase 3

0.59	GO:0006508	proteolysis
0.35	GO:0008063	Toll signaling pathway

0.76	GO:0008239	dipeptidyl-peptidase activity
0.65	GO:0008237	metallopeptidase activity
0.52	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.53	GO:0016607	nuclear speck
0.49	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome

sp|O55099|AURKB_RAT
Aurora kinase B
Search

AURKB

0.94	Aurora kinase B-A

0.72	GO:0035404	histone-serine phosphorylation
0.68	GO:0007051	spindle organization
0.64	GO:0000278	mitotic cell cycle
0.64	GO:0032467	positive regulation of cytokinesis
0.61	GO:0031577	spindle checkpoint
0.59	GO:0000280	nuclear division
0.59	GO:0032091	negative regulation of protein binding
0.58	GO:0070925	organelle assembly
0.57	GO:0036089	cleavage furrow formation
0.57	GO:0051321	meiotic cell cycle

0.68	GO:0004674	protein serine/threonine kinase activity
0.65	GO:0035173	histone kinase activity
0.55	GO:0019900	kinase binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding
0.52	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0046982	protein heterodimerization activity

0.74	GO:0032133	chromosome passenger complex
0.62	GO:0051233	spindle midzone
0.60	GO:0031616	spindle pole centrosome
0.59	GO:0030496	midbody
0.58	GO:0000793	condensed chromosome
0.56	GO:0005876	spindle microtubule
0.56	GO:0000775	chromosome, centromeric region
0.56	GO:0072686	mitotic spindle
0.54	GO:0044454	nuclear chromosome part
0.52	GO:0010369	chromocenter

0.68

GO:0004674

sp|O55145|X3CL1_RAT
Fractalkine
Search

CX3CL1

0.87	Fractalkine

0.88	GO:0050902	leukocyte adhesive activation
0.82	GO:0060326	cell chemotaxis
0.80	GO:0019221	cytokine-mediated signaling pathway
0.74	GO:0006955	immune response
0.73	GO:0051041	positive regulation of calcium-independent cell-cell adhesion
0.68	GO:0032914	positive regulation of transforming growth factor beta1 production
0.67	GO:0033622	integrin activation
0.67	GO:0002523	leukocyte migration involved in inflammatory response
0.66	GO:1905517	macrophage migration
0.66	GO:0060055	angiogenesis involved in wound healing

0.84	GO:0008009	chemokine activity
0.70	GO:0031737	CX3C chemokine receptor binding
0.63	GO:0005178	integrin binding
0.59	GO:0048020	CCR chemokine receptor binding

0.66	GO:0005576	extracellular region
0.60	GO:0009986	cell surface
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0098794	postsynapse
0.43	GO:0005886	plasma membrane
0.42	GO:0042995	cell projection
0.30	GO:0016021	integral component of membrane

sp|O55148|GAS7_RAT
Growth arrest-specific protein 7
Search

GAS7

0.97	Growth arrest-specific protein 7

0.70	GO:0007399	nervous system development
0.68	GO:0030154	cell differentiation
0.63	GO:0043009	chordate embryonic development
0.57	GO:0030041	actin filament polymerization
0.57	GO:0051017	actin filament bundle assembly
0.55	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.53	GO:0120036	plasma membrane bounded cell projection organization
0.50	GO:0008360	regulation of cell shape
0.49	GO:0007050	cell cycle arrest
0.40	GO:1903506	regulation of nucleic acid-templated transcription

0.54	GO:0051015	actin filament binding
0.45	GO:0042302	structural constituent of cuticle
0.41	GO:0003700	DNA binding transcription factor activity

0.57	GO:0001726	ruffle
0.57	GO:0005884	actin filament
0.42	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O55156|CLIP2_RAT
CAP-Gly domain-containing linker protein 2
Search

CLIP2

0.96	CAP-Gly domain-containing linker protein 2

0.44	GO:0031110	regulation of microtubule polymerization or depolymerization
0.43	GO:1902903	regulation of supramolecular fiber organization
0.42	GO:1901880	negative regulation of protein depolymerization
0.42	GO:0051494	negative regulation of cytoskeleton organization
0.38	GO:0044861	protein transport into plasma membrane raft
0.37	GO:0001578	microtubule bundle formation
0.36	GO:0032273	positive regulation of protein polymerization
0.36	GO:0051495	positive regulation of cytoskeleton organization

0.85	GO:0051010	microtubule plus-end binding
0.34	GO:0008270	zinc ion binding

0.85	GO:0035371	microtubule plus-end
0.84	GO:0005881	cytoplasmic microtubule
0.45	GO:1901588	dendritic microtubule
0.44	GO:0042599	lamellar body
0.41	GO:0005875	microtubule associated complex
0.38	GO:0044352	pinosome
0.36	GO:0005813	centrosome
0.36	GO:0005635	nuclear envelope
0.30	GO:0016020	membrane

tr|O55158|O55158_RAT
Tetraspanin
Search

TSPAN8

0.55	Tetraspanin

0.52	GO:0007283	spermatogenesis
0.45	GO:0007166	cell surface receptor signaling pathway
0.41	GO:0060255	regulation of macromolecule metabolic process
0.39	GO:0030195	negative regulation of blood coagulation
0.34	GO:0016477	cell migration
0.34	GO:0045807	positive regulation of endocytosis
0.34	GO:0050821	protein stabilization
0.34	GO:0008283	cell proliferation
0.33	GO:1901741	positive regulation of myoblast fusion
0.33	GO:0045661	regulation of myoblast differentiation

0.39

GO:0005178

integrin binding

0.50	GO:0009986	cell surface
0.43	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0030054	cell junction
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0001772	immunological synapse
0.33	GO:0005654	nucleoplasm

sp|O55159|EPCAM_RAT
Epithelial cell adhesion molecule
Search

EPCAM

0.96	Epithelial cell adhesion molecule

0.56	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin
0.55	GO:0001657	ureteric bud development
0.55	GO:0023019	signal transduction involved in regulation of gene expression
0.54	GO:2000648	positive regulation of stem cell proliferation
0.52	GO:0048863	stem cell differentiation
0.50	GO:0098609	cell-cell adhesion
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
0.44	GO:1900028	negative regulation of ruffle assembly
0.44	GO:2000738	positive regulation of stem cell differentiation

0.50	GO:0098641	cadherin binding involved in cell-cell adhesion
0.49	GO:0032403	protein complex binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0030983	mismatched DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0016328	lateral plasma membrane
0.56	GO:0016323	basolateral plasma membrane
0.54	GO:0005923	bicellular tight junction
0.52	GO:0016324	apical plasma membrane
0.49	GO:0009986	cell surface
0.44	GO:0005887	integral component of plasma membrane
0.43	GO:0045178	basal part of cell
0.42	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.38	GO:0048471	perinuclear region of cytoplasm

0.33

GO:0004222

sp|O55162|LYPD3_RAT
Ly6/PLAUR domain-containing protein 3
Search

LYPD3

0.97	Ly6/PLAUR domain-containing protein 3

0.80	GO:0007160	cell-matrix adhesion
0.49	GO:0006501	C-terminal protein lipidation

0.85

GO:0043236

laminin binding

0.60	GO:0031225	anchored component of membrane
0.53	GO:0005886	plasma membrane
0.51	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|O55164|MPDZ_RAT
Multiple PDZ domain protein
Search

MPDZ

0.84	Multiple PDZ domain crumbs cell polarity complex component

0.71	GO:0007155	cell adhesion
0.44	GO:0042552	myelination
0.39	GO:0035556	intracellular signal transduction
0.38	GO:0016032	viral process

0.83

GO:0008022

protein C-terminus binding

0.86	GO:0043220	Schmidt-Lanterman incisure
0.85	GO:0016327	apicolateral plasma membrane
0.80	GO:0016324	apical plasma membrane
0.79	GO:0005923	bicellular tight junction
0.71	GO:0031410	cytoplasmic vesicle
0.49	GO:0014069	postsynaptic density
0.48	GO:0030425	dendrite
0.47	GO:0045211	postsynaptic membrane
0.40	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

sp|O55165|KIF3C_RAT
Kinesin-like protein KIF3C
Search

sp|O55166|VPS52_RAT
Vacuolar protein sorting-associated protein 52 homolog
Search

VPS52

0.93	VPS52, GARP complex subunit

0.84	GO:0007041	lysosomal transport
0.84	GO:0032456	endocytic recycling
0.74	GO:0048611	embryonic ectodermal digestive tract development
0.73	GO:0010668	ectodermal cell differentiation
0.61	GO:0006896	Golgi to vacuole transport
0.58	GO:0042147	retrograde transport, endosome to Golgi

0.83	GO:0019905	syntaxin binding
0.58	GO:0017137	Rab GTPase binding

0.85	GO:1990745	EARP complex
0.85	GO:0000938	GARP complex
0.76	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|O55170|SOX10_RAT
Transcription factor SOX-10
Search

SOX10

0.97	LOW QUALITY PROTEIN: transcription factor SOX-10

0.58	GO:0030318	melanocyte differentiation
0.57	GO:0032808	lacrimal gland development
0.57	GO:0022010	central nervous system myelination
0.57	GO:0048484	enteric nervous system development
0.56	GO:0001755	neural crest cell migration
0.56	GO:0002052	positive regulation of neuroblast proliferation
0.55	GO:0007422	peripheral nervous system development
0.55	GO:0014015	positive regulation of gliogenesis
0.54	GO:0048546	digestive tract morphogenesis
0.54	GO:0090090	negative regulation of canonical Wnt signaling pathway

0.55	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003682	chromatin binding
0.49	GO:0042802	identical protein binding
0.49	GO:0008134	transcription factor binding
0.35	GO:0003713	transcription coactivator activity
0.35	GO:0019899	enzyme binding

0.60	GO:0005634	nucleus
0.57	GO:0031315	extrinsic component of mitochondrial outer membrane
0.46	GO:0070013	intracellular organelle lumen
0.38	GO:0000785	chromatin

sp|O55171|ACOT2_RAT
Acyl-coenzyme A thioesterase 2, mitochondrial
Search

0.55	Acyl-coenzyme A thioesterase 2, mitochondrial

0.73	GO:0035383	thioester metabolic process
0.64	GO:0032789	unsaturated monocarboxylic acid metabolic process
0.64	GO:0032788	saturated monocarboxylic acid metabolic process
0.63	GO:0006732	coenzyme metabolic process
0.61	GO:0000038	very long-chain fatty acid metabolic process
0.59	GO:0001676	long-chain fatty acid metabolic process
0.54	GO:0006793	phosphorus metabolic process
0.53	GO:0043649	dicarboxylic acid catabolic process
0.53	GO:0046459	short-chain fatty acid metabolic process
0.39	GO:0070849	response to epidermal growth factor

0.76	GO:0016790	thiolester hydrolase activity
0.52	GO:0005102	receptor binding
0.47	GO:0052689	carboxylic ester hydrolase activity

0.55	GO:0005777	peroxisome
0.42	GO:0005829	cytosol
0.41	GO:0005759	mitochondrial matrix
0.40	GO:0070062	extracellular exosome
0.37	GO:0031907	microbody lumen

0.76	EC:3.1.2	GO:0016790
0.47	KEGG:R00630	GO:0052689

sp|O55173|PDPK1_RAT
3-phosphoinositide-dependent protein kinase 1
Search

PDPK1

0.91	Phosphoinositide-dependent protein kinase-1 beta

0.63	GO:0006468	protein phosphorylation
0.56	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.55	GO:0032148	activation of protein kinase B activity
0.55	GO:0071364	cellular response to epidermal growth factor stimulus
0.55	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.55	GO:0010518	positive regulation of phospholipase activity
0.54	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.54	GO:1903078	positive regulation of protein localization to plasma membrane
0.54	GO:0007173	epidermal growth factor receptor signaling pathway
0.53	GO:0097191	extrinsic apoptotic signaling pathway

0.64	GO:0004672	protein kinase activity
0.56	GO:0016004	phospholipase activator activity
0.56	GO:0043274	phospholipase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.38	GO:0005158	insulin receptor binding
0.37	GO:0019901	protein kinase binding

0.49	GO:0014069	postsynaptic density
0.46	GO:0042995	cell projection
0.45	GO:0031410	cytoplasmic vesicle
0.41	GO:0005886	plasma membrane
0.38	GO:0043204	perikaryon
0.38	GO:0005925	focal adhesion
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|O55174|ZNT4_RAT
Zinc transporter 4
Search

SLC30A4

0.97	Zinc transporter 4

0.62	GO:0055069	zinc ion homeostasis
0.62	GO:0061088	regulation of sequestering of zinc ion
0.61	GO:0098655	cation transmembrane transport
0.53	GO:0006829	zinc II ion transport
0.50	GO:0010043	response to zinc ion
0.49	GO:0009636	response to toxic substance
0.46	GO:0072503	cellular divalent inorganic cation homeostasis
0.45	GO:0098660	inorganic ion transmembrane transport
0.44	GO:0046916	cellular transition metal ion homeostasis
0.39	GO:0051238	sequestering of metal ion

0.61	GO:0008324	cation transmembrane transporter activity
0.44	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.36	GO:0042803	protein homodimerization activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.56	GO:0005770	late endosome
0.39	GO:0005765	lysosomal membrane
0.38	GO:0010008	endosome membrane
0.38	GO:0030141	secretory granule
0.35	GO:0005886	plasma membrane
0.33	GO:0030658	transport vesicle membrane
0.32	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|O55193|CCR2_RAT
C-C chemokine receptor type 2
Search

CCR5

0.85	C-C motif chemokine receptor 2

0.83	GO:0070098	chemokine-mediated signaling pathway
0.79	GO:0006954	inflammatory response
0.73	GO:0006955	immune response
0.70	GO:0006935	chemotaxis
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:0090026	positive regulation of monocyte chemotaxis
0.63	GO:0001974	blood vessel remodeling
0.55	GO:2000464	positive regulation of astrocyte chemotaxis
0.53	GO:0043310	negative regulation of eosinophil degranulation
0.53	GO:2000473	positive regulation of hematopoietic stem cell migration

0.85	GO:0016493	C-C chemokine receptor activity
0.57	GO:0019957	C-C chemokine binding
0.54	GO:0031727	CCR2 chemokine receptor binding
0.42	GO:0003779	actin binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0019901	protein kinase binding

0.52	GO:0009897	external side of plasma membrane
0.42	GO:0005768	endosome
0.38	GO:0043204	perikaryon
0.38	GO:0030425	dendrite
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005829	cytosol
0.35	GO:0005887	integral component of plasma membrane

sp|O55197|C3AR_RAT
C3a anaphylatoxin chemotactic receptor
Search

C3AR1

0.97	Complement component 3A receptor 1

0.83	GO:0002430	complement receptor mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0010759	positive regulation of macrophage chemotaxis
0.66	GO:0006935	chemotaxis
0.64	GO:0090023	positive regulation of neutrophil chemotaxis
0.64	GO:0010575	positive regulation of vascular endothelial growth factor production
0.62	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.61	GO:0045766	positive regulation of angiogenesis
0.50	GO:0006954	inflammatory response
0.50	GO:0050900	leukocyte migration

0.84	GO:0004876	complement component C3a receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.45	GO:0004878	complement component C5a receptor activity
0.40	GO:0001850	complement component C3a binding
0.38	GO:0001653	peptide receptor activity
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0050254	rhodopsin kinase activity
0.33	GO:0042923	neuropeptide binding

0.45	GO:0005887	integral component of plasma membrane
0.37	GO:0035579	specific granule membrane
0.37	GO:0035577	azurophil granule membrane
0.34	GO:0005840	ribosome
0.33	GO:0009925	basal plasma membrane
0.33	GO:0045177	apical part of cell
0.32	GO:0043005	neuron projection

0.33

GO:0050254

sp|O55207|SYNJ2_RAT
Synaptojanin-2
Search

SYNJ2

0.87	Synaptojanin-2

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.53	GO:0048488	synaptic vesicle endocytosis
0.38	GO:1904980	positive regulation of endosome organization
0.38	GO:0046855	inositol phosphate dephosphorylation
0.38	GO:0051640	organelle localization
0.37	GO:0072318	clathrin coat disassembly
0.37	GO:0007420	brain development
0.37	GO:0098884	postsynaptic neurotransmitter receptor internalization
0.37	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.37	GO:0007268	chemical synaptic transmission

0.85	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.58	GO:0003723	RNA binding
0.43	GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity
0.41	GO:0052744	phosphatidylinositol monophosphate phosphatase activity
0.40	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity
0.38	GO:0046030	inositol trisphosphate phosphatase activity
0.37	GO:0017124	SH3 domain binding
0.37	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.36	GO:0030165	PDZ domain binding
0.35	GO:0008022	protein C-terminus binding

0.49	GO:0045202	synapse
0.40	GO:0098589	membrane region
0.39	GO:0043005	neuron projection
0.38	GO:0098590	plasma membrane region
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005856	cytoskeleton
0.37	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0099512	supramolecular fiber
0.37	GO:0031315	extrinsic component of mitochondrial outer membrane
0.37	GO:0030118	clathrin coat

0.37	EC:3.1.3	GO:0052629
0.34	KEGG:R03430	GO:0052659

sp|O55227|UNC50_RAT
Protein unc-50 homolog
Search

UNC50

0.97	Unc-50 inner nuclear membrane RNA binding protein (Fragment)

0.38	GO:0015031	protein transport
0.36	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process

0.37	GO:0003723	RNA binding
0.36	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity

0.50	GO:0005794	Golgi apparatus
0.45	GO:0031301	integral component of organelle membrane
0.44	GO:0098588	bounding membrane of organelle
0.43	GO:0031984	organelle subcompartment
0.42	GO:0005637	nuclear inner membrane

0.36

EC:3.1.3.66

GO:0016316

sp|O55232|OREX_RAT
Orexin
Search

HCRT

0.89	Hypocretin neuropeptide precursor

0.84	GO:0007631	feeding behavior
0.80	GO:0007218	neuropeptide signaling pathway
0.59	GO:0042746	circadian sleep/wake cycle, wakefulness
0.55	GO:0030431	sleep
0.54	GO:0033555	multicellular organismal response to stress
0.51	GO:0042594	response to starvation
0.36	GO:0035556	intracellular signal transduction
0.30	GO:0001659	temperature homeostasis
0.30	GO:0031645	negative regulation of neurological system process
0.30	GO:0031646	positive regulation of neurological system process

0.30	GO:0005515	protein binding
0.30	GO:0030545	receptor regulator activity

0.49	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0044456	synapse part
0.30	GO:0043229	intracellular organelle
0.30	GO:0012505	endomembrane system

sp|O70127|ABCBB_RAT
Bile salt export pump
Search

ABCB11

0.92	ATP binding cassette subfamily B member 11

0.80	GO:0015721	bile acid and bile salt transport
0.55	GO:0055085	transmembrane transport
0.53	GO:0046717	acid secretion

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.60	GO:0015126	canalicular bile acid transmembrane transporter activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0046581	intercellular canaliculus
0.63	GO:0045177	apical part of cell
0.30	GO:0016020	membrane

sp|O70132|FEV_RAT
Protein FEV
Search

FEV

0.97	FEV, ETS transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0048665	neuron fate specification
0.54	GO:0042551	neuron maturation
0.52	GO:0010604	positive regulation of macromolecule metabolic process
0.51	GO:2000504	positive regulation of blood vessel remodeling
0.51	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation
0.49	GO:0003197	endocardial cushion development
0.46	GO:0016477	cell migration

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0003690	double-stranded DNA binding
0.35	GO:0003714	transcription corepressor activity
0.34	GO:0035326	enhancer binding
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005515	protein binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.61	GO:0005634	nucleus
0.46	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0043025	neuronal cell body
0.33	GO:0019773	proteasome core complex, alpha-subunit complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016773

sp|O70141|SEM6B_RAT
Semaphorin-6B
Search

SEMA6B

0.91	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba

0.45	GO:2001224	positive regulation of neuron migration
0.44	GO:0051642	centrosome localization
0.43	GO:0001764	neuron migration
0.43	GO:0071526	semaphorin-plexin signaling pathway
0.43	GO:0007411	axon guidance
0.36	GO:1903671	negative regulation of sprouting angiogenesis
0.34	GO:0006915	apoptotic process

0.60	GO:0030215	semaphorin receptor binding
0.40	GO:0099600	transmembrane receptor activity
0.39	GO:0038023	signaling receptor activity
0.35	GO:0042802	identical protein binding

0.45	GO:0005887	integral component of plasma membrane
0.34	GO:0030424	axon

sp|O70142|SHC2_RAT
SHC-transforming protein 2
Search

SHC2

0.88	RNA polymerase mitochondrial

0.76	GO:0000187	activation of MAPK activity
0.62	GO:0035556	intracellular signal transduction
0.51	GO:0032502	developmental process
0.49	GO:0032501	multicellular organismal process
0.48	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.43	GO:0042127	regulation of cell proliferation
0.40	GO:0035249	synaptic transmission, glutamatergic
0.38	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.38	GO:0007610	behavior
0.38	GO:0071363	cellular response to growth factor stimulus

0.81	GO:0030971	receptor tyrosine kinase binding
0.43	GO:0001784	phosphotyrosine residue binding
0.40	GO:0048408	epidermal growth factor binding
0.40	GO:0005168	neurotrophin TRKA receptor binding
0.39	GO:0005159	insulin-like growth factor receptor binding
0.39	GO:0005158	insulin receptor binding
0.39	GO:0046875	ephrin receptor binding
0.37	GO:0019904	protein domain specific binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.45	GO:0005622	intracellular
0.40	GO:0005886	plasma membrane
0.34	GO:0009295	nucleoid
0.33	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.33	GO:0043233	organelle lumen
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.33

EC:2.7.7.6

GO:0003899

sp|O70143|SHC3_RAT
SHC-transforming protein 3
Search

SHC3

0.90	SHC-transforming protein 3

0.73	GO:0007417	central nervous system development
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0035249	synaptic transmission, glutamatergic
0.54	GO:0007611	learning or memory
0.51	GO:0048863	stem cell differentiation
0.50	GO:0007173	epidermal growth factor receptor signaling pathway
0.49	GO:0008284	positive regulation of cell proliferation
0.41	GO:0001525	angiogenesis
0.41	GO:0006915	apoptotic process
0.37	GO:0098535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation

0.61	GO:0030971	receptor tyrosine kinase binding
0.57	GO:0001784	phosphotyrosine residue binding
0.41	GO:0019904	protein domain specific binding
0.36	GO:0004713	protein tyrosine kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0048408	epidermal growth factor binding
0.34	GO:0005168	neurotrophin TRKA receptor binding
0.34	GO:0004871	signal transducer activity
0.34	GO:0005159	insulin-like growth factor receptor binding
0.34	GO:0005158	insulin receptor binding

0.45	GO:0005622	intracellular
0.40	GO:0005886	plasma membrane
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0098794	postsynapse
0.33	GO:0044422	organelle part
0.33	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.36

EC:2.7.10

GO:0004713

tr|O70149|O70149_RAT
High sulfur protein B2F
Search

KAP1.3

0.97	Keratin intermediate-filament type I protein variant 2

0.83

GO:0045095

keratin filament

sp|O70150|KCC1B_RAT
Calcium/calmodulin-dependent protein kinase type 1B
Search

PNCK

0.54	Pregnancy up-regulated non-ubiquitously expressed CaM kinase

0.63	GO:0006468	protein phosphorylation
0.47	GO:0018210	peptidyl-threonine modification
0.47	GO:0018209	peptidyl-serine modification
0.41	GO:0045475	locomotor rhythm
0.41	GO:0035556	intracellular signal transduction
0.37	GO:0043009	chordate embryonic development
0.34	GO:0045664	regulation of neuron differentiation
0.33	GO:0006633	fatty acid biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.64	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005516	calmodulin binding
0.34	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

0.41	GO:0005954	calcium- and calmodulin-dependent protein kinase complex
0.36	GO:0012505	endomembrane system
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.64

GO:0004674

tr|O70153|O70153_RAT
B29/Ig-beta/CD79b
Search

CD79B

0.97	B-cell antigen receptor complex-associated protein beta chain

0.69	GO:0007166	cell surface receptor signaling pathway
0.64	GO:0002757	immune response-activating signal transduction
0.61	GO:0051260	protein homooligomerization
0.53	GO:0030183	B cell differentiation
0.41	GO:0002250	adaptive immune response
0.37	GO:0035725	sodium ion transmembrane transport
0.35	GO:0010469	regulation of receptor activity
0.35	GO:0034765	regulation of ion transmembrane transport

0.67	GO:0004888	transmembrane signaling receptor activity
0.59	GO:0042803	protein homodimerization activity
0.38	GO:0005248	voltage-gated sodium channel activity
0.35	GO:0005179	hormone activity
0.35	GO:0005244	voltage-gated ion channel activity

0.72	GO:0019815	B cell receptor complex
0.65	GO:0009897	external side of plasma membrane
0.57	GO:0005794	Golgi apparatus
0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol
0.46	GO:0005887	integral component of plasma membrane
0.41	GO:0070062	extracellular exosome
0.38	GO:0034706	sodium channel complex

sp|O70156|OLR1_RAT
Oxidized low-density lipoprotein receptor 1
Search

0.61	Oxidized low density lipoprotein receptor 1

0.45	GO:0006954	inflammatory response
0.42	GO:0007155	cell adhesion
0.42	GO:0002376	immune system process
0.41	GO:0008015	blood circulation
0.40	GO:0016192	vesicle-mediated transport
0.39	GO:0032930	positive regulation of superoxide anion generation
0.38	GO:0098657	import into cell
0.38	GO:0035296	regulation of tube diameter
0.38	GO:0003018	vascular process in circulatory system
0.38	GO:0001775	cell activation

0.68	GO:0030246	carbohydrate binding
0.58	GO:0042802	identical protein binding
0.42	GO:0005041	low-density lipoprotein receptor activity
0.35	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.35	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.34	GO:0003682	chromatin binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0043235	receptor complex
0.57	GO:0005654	nucleoplasm
0.48	GO:0005886	plasma membrane
0.45	GO:0045121	membrane raft
0.41	GO:0005576	extracellular region
0.39	GO:0035579	specific granule membrane
0.39	GO:0070821	tertiary granule membrane
0.35	GO:0001674	female germ cell nucleus
0.35	GO:0001673	male germ cell nucleus
0.35	GO:0005700	polytene chromosome

sp|O70173|P3C2G_RAT
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
Search

PIK3C2G

0.96	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma

0.81	GO:0048015	phosphatidylinositol-mediated signaling
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.52	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.47	GO:0016477	cell migration
0.39	GO:0001525	angiogenesis
0.39	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.38	GO:0006935	chemotaxis
0.38	GO:0039694	viral RNA genome replication
0.37	GO:0048268	clathrin coat assembly
0.37	GO:0006897	endocytosis

0.75	GO:0035004	phosphatidylinositol 3-kinase activity
0.74	GO:0035091	phosphatidylinositol binding
0.66	GO:0016307	phosphatidylinositol phosphate kinase activity
0.52	GO:0052742	phosphatidylinositol kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003735	structural constituent of ribosome

0.48	GO:0005942	phosphatidylinositol 3-kinase complex
0.45	GO:0005622	intracellular
0.40	GO:0005886	plasma membrane
0.37	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.34	GO:0031975	envelope
0.34	GO:0044422	organelle part
0.33	GO:1990904	ribonucleoprotein complex
0.32	GO:0043228	non-membrane-bounded organelle

0.75

GO:0035004

tr|O70185|O70185_RAT
Nuclear factor 1
Search

NFIB

0.79	Nuclear factor 1 B-type

0.66	GO:0006260	DNA replication
0.63	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis
0.63	GO:0061141	lung ciliated cell differentiation
0.63	GO:0021740	principal sensory nucleus of trigeminal nerve development
0.63	GO:2000790	regulation of mesenchymal cell proliferation involved in lung development
0.62	GO:0060486	Clara cell differentiation
0.62	GO:0060509	Type I pneumocyte differentiation
0.62	GO:0060510	Type II pneumocyte differentiation
0.61	GO:0021960	anterior commissure morphogenesis
0.61	GO:0072201	negative regulation of mesenchymal cell proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001106	RNA polymerase II transcription corepressor activity

0.61	GO:0044300	cerebellar mossy fiber
0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part

tr|O70188|O70188_RAT
Nuclear factor 1
Search

NFIC

0.78	Nuclear factor 1 C-type

0.65	GO:0006260	DNA replication
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0042475	odontogenesis of dentin-containing tooth
0.47	GO:0051254	positive regulation of RNA metabolic process
0.47	GO:0010557	positive regulation of macromolecule biosynthetic process
0.47	GO:0031328	positive regulation of cellular biosynthetic process
0.46	GO:0051253	negative regulation of RNA metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|O70196|PPCE_RAT
Prolyl endopeptidase
Search

PREP

0.66	Prolyl endopeptidase

0.59

GO:0006508

proteolysis

0.71	GO:0070008	serine-type exopeptidase activity
0.67	GO:0004252	serine-type endopeptidase activity
0.35	GO:0042277	peptide binding
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005515	protein binding

0.49	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0070008

sp|O70199|UGDH_RAT
UDP-glucose 6-dehydrogenase
Search

UGDH

0.45	UDP-glucose 6-dehydrogenase

0.56	GO:0001702	gastrulation with mouth forming second
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0003190	atrioventricular valve formation
0.46	GO:0045880	positive regulation of smoothened signaling pathway
0.45	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.45	GO:0007368	determination of left/right symmetry
0.44	GO:0006024	glycosaminoglycan biosynthetic process
0.43	GO:0006065	UDP-glucuronate biosynthetic process
0.34	GO:0006011	UDP-glucose metabolic process
0.34	GO:0000271	polysaccharide biosynthetic process

0.77	GO:0003979	UDP-glucose 6-dehydrogenase activity
0.68	GO:0051287	NAD binding
0.33	GO:0009055	electron transfer activity

0.48	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.77	EC:1.1.1.22	GO:0003979
0.77	KEGG:R00286	GO:0003979

sp|O70210|CHAD_RAT
Chondroadherin
Search

CHAD

0.97	Chondroadherin

0.84	GO:1900155	negative regulation of bone trabecula formation
0.75	GO:0060348	bone development
0.64	GO:0046426	negative regulation of JAK-STAT cascade
0.60	GO:0006469	negative regulation of protein kinase activity
0.60	GO:0019221	cytokine-mediated signaling pathway
0.57	GO:1904027	negative regulation of collagen fibril organization
0.54	GO:0032331	negative regulation of chondrocyte differentiation
0.40	GO:0001502	cartilage condensation
0.35	GO:0048699	generation of neurons
0.34	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.62	GO:0004860	protein kinase inhibitor activity
0.57	GO:0098633	collagen fibril binding
0.52	GO:0005518	collagen binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0030246	carbohydrate binding

0.54	GO:0031012	extracellular matrix
0.41	GO:0005737	cytoplasm
0.32	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.33

GO:0004674

sp|O70215|NKG2D_RAT
NKG2-D type II integral membrane protein
Search

KLRK1

0.96	Killer cell lectin like receptor K1

0.69	GO:2000502	negative regulation of natural killer cell chemotaxis
0.68	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
0.66	GO:0042267	natural killer cell mediated cytotoxicity
0.65	GO:0034260	negative regulation of GTPase activity
0.65	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.62	GO:0030101	natural killer cell activation
0.62	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.62	GO:0032729	positive regulation of interferon-gamma production
0.61	GO:0050830	defense response to Gram-positive bacterium
0.60	GO:0071222	cellular response to lipopolysaccharide

0.69	GO:0030246	carbohydrate binding
0.68	GO:0032394	MHC class Ib receptor activity
0.64	GO:0042288	MHC class I protein binding
0.55	GO:0042803	protein homodimerization activity
0.41	GO:0019900	kinase binding

0.59	GO:0009986	cell surface
0.55	GO:0098552	side of membrane
0.48	GO:0044459	plasma membrane part
0.30	GO:0016021	integral component of membrane

sp|O70239|AXIN1_RAT
Axin-1
Search

AXIN1

0.93	Axin protein 1 transcript variant 1

0.74	GO:0016055	Wnt signaling pathway
0.55	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.54	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.54	GO:0032147	activation of protein kinase activity
0.53	GO:0045732	positive regulation of protein catabolic process
0.50	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0048320	axial mesoderm formation
0.49	GO:0030910	olfactory placode formation
0.49	GO:0001743	optic placode formation
0.49	GO:0021797	forebrain anterior/posterior pattern specification

0.85	GO:0030159	receptor signaling complex scaffold activity
0.58	GO:0070411	I-SMAD binding
0.55	GO:0008013	beta-catenin binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0042802	identical protein binding
0.45	GO:0004871	signal transducer activity
0.44	GO:0005096	GTPase activator activity
0.38	GO:0046983	protein dimerization activity
0.38	GO:0070016	armadillo repeat domain binding
0.38	GO:0070412	R-SMAD binding

0.86	GO:0030877	beta-catenin destruction complex
0.55	GO:0016328	lateral plasma membrane
0.52	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005634	nucleus
0.38	GO:1990909	Wnt signalosome
0.37	GO:0031410	cytoplasmic vesicle
0.37	GO:0005881	cytoplasmic microtubule
0.36	GO:0005938	cell cortex
0.35	GO:0014069	postsynaptic density
0.35	GO:0005829	cytosol

sp|O70240|AXIN2_RAT
Axin-2
Search

AXIN2

0.97	Axin 2 (conductin, axil)

0.76	GO:0016055	Wnt signaling pathway
0.70	GO:0032423	regulation of mismatch repair
0.69	GO:0070602	regulation of centromeric sister chromatid cohesion
0.68	GO:0001957	intramembranous ossification
0.68	GO:0035414	negative regulation of catenin import into nucleus
0.67	GO:0003139	secondary heart field specification
0.66	GO:0061181	regulation of chondrocyte development
0.66	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis
0.66	GO:0048255	mRNA stabilization
0.66	GO:0010718	positive regulation of epithelial to mesenchymal transition

0.66	GO:0070411	I-SMAD binding
0.61	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0005096	GTPase activator activity
0.39	GO:0008013	beta-catenin binding
0.36	GO:0019901	protein kinase binding

0.60	GO:0005813	centrosome
0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.40	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|O70244|CUBN_RAT
Cubilin
Search

0.10

Cubilin

0.47	GO:0042953	lipoprotein transport
0.45	GO:0006898	receptor-mediated endocytosis
0.43	GO:0006508	proteolysis
0.34	GO:0007219	Notch signaling pathway
0.33	GO:0007275	multicellular organism development
0.32	GO:0032259	methylation
0.30	GO:0020028	hemoglobin import
0.30	GO:0042221	response to chemical
0.30	GO:0009111	vitamin catabolic process
0.30	GO:0042737	drug catabolic process

0.67	GO:0005509	calcium ion binding
0.47	GO:0004222	metalloendopeptidase activity
0.46	GO:0042803	protein homodimerization activity
0.34	GO:0005112	Notch binding
0.33	GO:0005044	scavenger receptor activity
0.32	GO:0008168	methyltransferase activity
0.30	GO:0048037	cofactor binding
0.30	GO:1901363	heterocyclic compound binding
0.30	GO:0036094	small molecule binding
0.30	GO:0008144	drug binding

0.49	GO:0005903	brush border
0.48	GO:0016324	apical plasma membrane
0.48	GO:0030139	endocytic vesicle
0.48	GO:0070062	extracellular exosome
0.48	GO:0005905	clathrin-coated pit
0.46	GO:0005768	endosome
0.44	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0120038	plasma membrane bounded cell projection part

0.47

GO:0004222

sp|O70247|SC5A6_RAT
Sodium-dependent multivitamin transporter
Search

SLC5A6

0.91	Sodium-dependent multivitamin transporter

0.55	GO:0055085	transmembrane transport
0.39	GO:0015878	biotin transport
0.38	GO:0006814	sodium ion transport
0.38	GO:0072337	modified amino acid transport
0.34	GO:0006768	biotin metabolic process
0.34	GO:0015939	pantothenate metabolic process

0.57

GO:0022857

transmembrane transporter activity

0.39	GO:0031526	brush border membrane
0.38	GO:0012506	vesicle membrane
0.34	GO:0005887	integral component of plasma membrane

sp|O70248|APBA3_RAT
Amyloid beta A4 precursor protein-binding family A member 3
Search

APBA3

0.93	Amyloid beta precursor protein binding family A member 3

0.68	GO:0043086	negative regulation of catalytic activity
0.59	GO:0007268	chemical synaptic transmission
0.53	GO:0001701	in utero embryonic development
0.43	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0006461	protein complex assembly
0.37	GO:0015031	protein transport
0.36	GO:0035264	multicellular organism growth
0.36	GO:0007626	locomotory behavior
0.33	GO:0014051	gamma-aminobutyric acid secretion
0.33	GO:0014047	glutamate secretion

0.85	GO:0001540	amyloid-beta binding
0.70	GO:0004857	enzyme inhibitor activity
0.49	GO:0019899	enzyme binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0008021	synaptic vesicle
0.32	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|O70249|OGG1_RAT
N-glycosylase/DNA lyase
Search

OGG1

0.52	8-oxoguanine DNA glycosylase

0.72	GO:0006289	nucleotide-excision repair
0.72	GO:0006284	base-excision repair
0.63	GO:1901291	negative regulation of double-strand break repair via single-strand annealing
0.60	GO:0033158	regulation of protein import into nucleus, translocation
0.53	GO:0009314	response to radiation
0.50	GO:0006979	response to oxidative stress
0.47	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0051593	response to folic acid
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.78	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.72	GO:0003684	damaged DNA binding
0.54	GO:0008017	microtubule binding
0.48	GO:0016829	lyase activity
0.34	GO:0004519	endonuclease activity
0.33	GO:0046872	metal ion binding

0.57	GO:0016363	nuclear matrix
0.55	GO:0016607	nuclear speck
0.46	GO:0005739	mitochondrion
0.45	GO:0043234	protein complex
0.32	GO:0000775	chromosome, centromeric region
0.30	GO:0016020	membrane

0.78

EC:3.2.2.23

GO:0008534

sp|O70257|STX7_RAT
Syntaxin-7
Search

STX7

0.93	Syntaxin 7 (Predicted)

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.61	GO:1902685	positive regulation of receptor localization to synapse
0.59	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.57	GO:1903076	regulation of protein localization to plasma membrane
0.54	GO:0051640	organelle localization
0.51	GO:0070925	organelle assembly
0.48	GO:0065009	regulation of molecular function
0.47	GO:0048284	organelle fusion

0.80	GO:0005484	SNAP receptor activity
0.60	GO:0019869	chloride channel inhibitor activity
0.57	GO:0000149	SNARE binding
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.34	GO:0032403	protein complex binding
0.34	GO:0005507	copper ion binding

0.59	GO:0070820	tertiary granule
0.59	GO:0005766	primary lysosome
0.58	GO:0001772	immunological synapse
0.56	GO:0055037	recycling endosome
0.56	GO:0030139	endocytic vesicle
0.55	GO:0005769	early endosome
0.55	GO:0005770	late endosome
0.54	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0031201	SNARE complex
0.39	GO:0098805	whole membrane

0.34

EC:1.14.17

GO:0016715

sp|O70260|PIAS3_RAT
E3 SUMO-protein ligase PIAS3
Search

PIAS3

0.92	Protein inhibitor of activated STAT 3

0.77	GO:0016925	protein sumoylation
0.64	GO:0033235	positive regulation of protein sumoylation
0.64	GO:0033234	negative regulation of protein sumoylation
0.50	GO:0060766	negative regulation of androgen receptor signaling pathway
0.49	GO:0045667	regulation of osteoblast differentiation
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0006351	transcription, DNA-templated

0.78	GO:0019789	SUMO transferase activity
0.63	GO:0008270	zinc ion binding
0.60	GO:0008022	protein C-terminus binding
0.57	GO:0019899	enzyme binding
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.45	GO:0008134	transcription factor binding
0.39	GO:0003677	DNA binding

0.51	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.41	GO:0005737	cytoplasm
0.39	GO:0044446	intracellular organelle part

sp|O70276|RPE65_RAT
Retinoid isomerohydrolase
Search

RPE65

0.97	Retinal Mueller cells isomerohydrolase

0.66	GO:0001523	retinoid metabolic process
0.62	GO:1901827	zeaxanthin biosynthetic process
0.61	GO:0034308	primary alcohol metabolic process
0.61	GO:0034754	cellular hormone metabolic process
0.57	GO:0007468	regulation of rhodopsin gene expression
0.56	GO:0050908	detection of light stimulus involved in visual perception
0.56	GO:0071257	cellular response to electrical stimulus
0.55	GO:0001895	retina homeostasis
0.54	GO:0008286	insulin receptor signaling pathway
0.54	GO:0060042	retina morphogenesis in camera-type eye

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.71	GO:0052885	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
0.68	GO:1901612	cardiolipin binding
0.67	GO:0031210	phosphatidylcholine binding
0.66	GO:0001786	phosphatidylserine binding
0.60	GO:0004744	retinal isomerase activity
0.53	GO:0046872	metal ion binding
0.50	GO:0052884	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
0.36	GO:0050251	retinol isomerase activity
0.34	GO:0005515	protein binding

0.40	GO:0005783	endoplasmic reticulum
0.38	GO:0044297	cell body
0.37	GO:0031090	organelle membrane
0.37	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol

0.75	EC:1.13.11	GO:0016702
0.71	KEGG:R08388	GO:0052885

sp|O70277|TRIM3_RAT
Tripartite motif-containing protein 3
Search

0.72	Tripartite motif-containing protein 3

0.42	GO:0016567	protein ubiquitination
0.39	GO:0060215	primitive hemopoiesis
0.38	GO:0030099	myeloid cell differentiation
0.30	GO:0008104	protein localization
0.30	GO:0006810	transport

0.63	GO:0008270	zinc ion binding
0.42	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0061659	ubiquitin-like protein ligase activity
0.30	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.30	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0097447	dendritic tree
0.30	GO:0031982	vesicle
0.30	GO:0012505	endomembrane system

0.42

GO:0004842

sp|O70280|WFDC1_RAT
WAP four-disulfide core domain protein 1
Search

WFDC1

0.97	WAP four-disulfide core domain protein 1

0.75	GO:0010466	negative regulation of peptidase activity
0.55	GO:0061045	negative regulation of wound healing
0.54	GO:0050728	negative regulation of inflammatory response
0.48	GO:0001558	regulation of cell growth
0.42	GO:0032355	response to estradiol
0.42	GO:0050680	negative regulation of epithelial cell proliferation
0.40	GO:0052548	regulation of endopeptidase activity
0.39	GO:0042493	response to drug
0.39	GO:0070588	calcium ion transmembrane transport
0.37	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.75	GO:0030414	peptidase inhibitor activity
0.40	GO:0061135	endopeptidase regulator activity
0.39	GO:0005388	calcium-transporting ATPase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.65	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.39

GO:0005388

sp|O70301|PSPN_RAT
Persephin
Search

PSPN

0.97

Persephin

0.76	GO:0010469	regulation of receptor activity
0.48	GO:0001658	branching involved in ureteric bud morphogenesis
0.39	GO:0007411	axon guidance
0.39	GO:0000165	MAPK cascade
0.39	GO:0007417	central nervous system development

0.78	GO:0008083	growth factor activity
0.39	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.66	GO:0005576	extracellular region
0.33	GO:0005622	intracellular

sp|O70351|HCD2_RAT
3-hydroxyacyl-CoA dehydrogenase type-2
Search

HSD17B10

0.96	Hydroxysteroid 17-beta dehydrogenase 10

0.68	GO:0097745	mitochondrial tRNA 5'-end processing
0.67	GO:1990180	mitochondrial tRNA 3'-end processing
0.66	GO:0070901	mitochondrial tRNA methylation
0.62	GO:0051289	protein homotetramerization
0.57	GO:0007005	mitochondrion organization
0.53	GO:0055114	oxidation-reduction process

0.67	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.58	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.53	GO:0000049	tRNA binding

0.67

GO:0030678

mitochondrial ribonuclease P complex

0.67

EC:1.1.1.51

GO:0030283

sp|O70352|CD82_RAT
CD82 antigen
Search

CD82

0.61	Tetraspanin

0.43

GO:0007166

cell surface receptor signaling pathway

0.41

GO:0005887

integral component of plasma membrane

sp|O70367|LECT1_RAT
Leukocyte cell-derived chemotaxin 1
Search

CNMD

0.97	Leukocyte cell-derived chemotaxin 1

0.63	GO:0016525	negative regulation of angiogenesis
0.44	GO:0051216	cartilage development
0.41	GO:0030154	cell differentiation
0.40	GO:0007585	respiratory gaseous exchange
0.40	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.39	GO:0001937	negative regulation of endothelial cell proliferation
0.39	GO:0003158	endothelium development
0.37	GO:0000902	cell morphogenesis
0.36	GO:0006029	proteoglycan metabolic process
0.36	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.35

GO:0005509

calcium ion binding

0.42	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0012505	endomembrane system
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O70377|SNP23_RAT
Synaptosomal-associated protein 23
Search

SNAP23

0.77	Synaptosomal-associated protein (Fragment)

0.80	GO:0002441	histamine secretion involved in inflammatory response
0.76	GO:0002279	mast cell activation involved in immune response
0.76	GO:0002448	mast cell mediated immunity
0.75	GO:0006887	exocytosis
0.74	GO:0032418	lysosome localization
0.71	GO:0051656	establishment of organelle localization
0.67	GO:0046907	intracellular transport
0.67	GO:0099643	signal release from synapse
0.66	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.61	GO:1990926	short-term synaptic potentiation

0.81	GO:0019905	syntaxin binding
0.58	GO:0005484	SNAP receptor activity

0.81	GO:0031201	SNARE complex
0.75	GO:0042629	mast cell granule
0.75	GO:0005766	primary lysosome
0.75	GO:0042581	specific granule
0.71	GO:0005913	cell-cell adherens junction
0.64	GO:0098793	presynapse
0.62	GO:0005654	nucleoplasm
0.57	GO:0031083	BLOC-1 complex
0.55	GO:0043209	myelin sheath
0.55	GO:0005886	plasma membrane

sp|O70417|PIP_RAT
Prolactin-inducible protein homolog
Search

PIP

0.89	Prolactin-inducible protein homolog

0.64	GO:0070233	negative regulation of T cell apoptotic process
0.63	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.54	GO:0002682	regulation of immune system process
0.54	GO:0010628	positive regulation of gene expression
0.49	GO:0001895	retina homeostasis
0.47	GO:0006508	proteolysis

0.66	GO:0019864	IgG binding
0.53	GO:0070001	aspartic-type peptidase activity
0.52	GO:0046983	protein dimerization activity
0.50	GO:0004175	endopeptidase activity

0.66	GO:0005576	extracellular region
0.61	GO:0016324	apical plasma membrane
0.48	GO:0005634	nucleus
0.44	GO:0031982	vesicle

sp|O70418|RN112_RAT
RING finger protein 112
Search

RNF112

0.97	RING finger protein 112

0.60	GO:0045687	positive regulation of glial cell differentiation
0.60	GO:0071158	positive regulation of cell cycle arrest
0.57	GO:0045666	positive regulation of neuron differentiation
0.35	GO:0016567	protein ubiquitination
0.34	GO:0006855	drug transmembrane transport
0.33	GO:0097264	self proteolysis
0.32	GO:0045087	innate immune response
0.32	GO:0016558	protein import into peroxisome matrix
0.32	GO:0051607	defense response to virus
0.32	GO:0006914	autophagy

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0015238	drug transmembrane transporter activity
0.34	GO:0015297	antiporter activity
0.31	GO:0030554	adenyl nucleotide binding

0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.32	GO:0031301	integral component of organelle membrane
0.32	GO:0098805	whole membrane
0.32	GO:0098588	bounding membrane of organelle
0.31	GO:0044446	intracellular organelle part

0.35

GO:0004842

sp|O70436|SMAD2_RAT
Mothers against decapentaplegic homolog 2
Search

SMAD2

0.64	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.59	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
0.59	GO:0007352	zygotic specification of dorsal/ventral axis
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0007182	common-partner SMAD protein phosphorylation
0.58	GO:0038092	nodal signaling pathway
0.58	GO:0007183	SMAD protein complex assembly
0.57	GO:0048340	paraxial mesoderm morphogenesis
0.57	GO:0070723	response to cholesterol
0.57	GO:0048617	embryonic foregut morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.57	GO:0070410	co-SMAD binding
0.57	GO:0070878	primary miRNA binding
0.57	GO:0070411	I-SMAD binding
0.57	GO:0034713	type I transforming growth factor beta receptor binding
0.57	GO:0070412	R-SMAD binding
0.56	GO:0097718	disordered domain specific binding
0.55	GO:0033613	activating transcription factor binding
0.55	GO:0003677	DNA binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.57	GO:0071141	SMAD protein complex
0.49	GO:0000785	chromatin
0.49	GO:0005737	cytoplasm
0.47	GO:0070013	intracellular organelle lumen
0.35	GO:0097708	intracellular vesicle
0.30	GO:0016020	membrane

sp|O70437|SMAD4_RAT
Mothers against decapentaplegic homolog 4
Search

SMAD4

0.65	Mothers against decapentaplegic homolog

0.82	GO:0007179	transforming growth factor beta receptor signaling pathway
0.60	GO:0003251	positive regulation of cell proliferation involved in heart valve morphogenesis
0.60	GO:1905305	negative regulation of cardiac myofibril assembly
0.60	GO:0061040	female gonad morphogenesis
0.60	GO:0003220	left ventricular cardiac muscle tissue morphogenesis
0.60	GO:0072134	nephrogenic mesenchyme morphogenesis
0.59	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.59	GO:0033686	positive regulation of luteinizing hormone secretion
0.59	GO:0072133	metanephric mesenchyme morphogenesis
0.59	GO:0003360	brainstem development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0030616	transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
0.59	GO:0043199	sulfate binding
0.57	GO:0070411	I-SMAD binding
0.57	GO:0070412	R-SMAD binding
0.55	GO:0001085	RNA polymerase II transcription factor binding
0.54	GO:0005518	collagen binding
0.54	GO:0003677	DNA binding
0.52	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.52	GO:0003682	chromatin binding

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.58	GO:0071141	SMAD protein complex
0.52	GO:0005813	centrosome
0.49	GO:0000785	chromatin
0.48	GO:0005737	cytoplasm
0.47	GO:0070013	intracellular organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|O70441|SYN3_RAT
Synapsin-3
Search

SYN3

0.94	Synapsin IIIa

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0051649	establishment of localization in cell
0.37	GO:0032228	regulation of synaptic transmission, GABAergic

0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0032555	purine ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.82	GO:0008021	synaptic vesicle
0.58	GO:0099501	exocytic vesicle membrane
0.57	GO:0014069	postsynaptic density
0.39	GO:0030054	cell junction

sp|O70444|PIM3_RAT
Serine/threonine-protein kinase pim-3
Search

PIM3

0.93	Proto-oncogene serine/threonine-protein kinase pim-1

0.77	GO:0043066	negative regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.51	GO:0007346	regulation of mitotic cell cycle
0.50	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.50	GO:1905062	positive regulation of cardioblast proliferation
0.48	GO:0070561	vitamin D receptor signaling pathway
0.48	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.46	GO:0043433	negative regulation of DNA binding transcription factor activity
0.45	GO:0008283	cell proliferation
0.41	GO:0006915	apoptotic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0043024	ribosomal small subunit binding
0.43	GO:0008134	transcription factor binding
0.43	GO:0030145	manganese ion binding
0.33	GO:0005509	calcium ion binding

0.48	GO:0005829	cytosol
0.43	GO:0005730	nucleolus
0.33	GO:0005886	plasma membrane
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

sp|O70453|HMOX3_RAT
Putative heme oxygenase 3
Search

0.54	Heme oxygenase 2

0.82	GO:0006788	heme oxidation
0.51	GO:0042167	heme catabolic process
0.47	GO:0055072	iron ion homeostasis
0.46	GO:0006979	response to oxidative stress
0.38	GO:0001666	response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0046916	cellular transition metal ion homeostasis

0.82	GO:0004392	heme oxygenase (decyclizing) activity
0.47	GO:0046872	metal ion binding
0.42	GO:0020037	heme binding
0.34	GO:0005515	protein binding

0.38	GO:0005783	endoplasmic reticulum
0.35	GO:0035579	specific granule membrane
0.34	GO:0005886	plasma membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.82

EC:1.14.99.3

GO:0004392

sp|O70454|BUD31_RAT
Protein BUD31 homolog
Search

BUD31

0.90	Putative g10 protein/ nuclear transcription regulator

0.57	GO:2000825	positive regulation of androgen receptor activity
0.51	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0007275	multicellular organism development

0.53	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.53	GO:0035257	nuclear hormone receptor binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.48	GO:0000785	chromatin
0.46	GO:0031974	membrane-enclosed lumen
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

sp|O70461|MOT3_RAT
Monocarboxylate transporter 3
Search

SLC16A3

0.92	Proton-coupled monocarboxylate transporter 3

0.81	GO:0035873	lactate transmembrane transport
0.36	GO:0050900	leukocyte migration
0.34	GO:0006090	pyruvate metabolic process

0.81	GO:0015129	lactate transmembrane transporter activity
0.39	GO:0015293	symporter activity
0.36	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.52	GO:0031965	nuclear membrane
0.36	GO:0009925	basal plasma membrane

sp|O70467|ANM3_RAT
Protein arginine N-methyltransferase 3
Search

PRMT3

0.95	Heterogeneous nuclear ribonucleoprotein methyltransferase-like 3 (S. cerevisiae)

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.56	GO:0018195	peptidyl-arginine modification
0.56	GO:0031397	negative regulation of protein ubiquitination
0.46	GO:0016570	histone modification
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:0010468	regulation of gene expression
0.36	GO:0060997	dendritic spine morphogenesis
0.33	GO:0043242	negative regulation of protein complex disassembly

0.63	GO:0008168	methyltransferase activity
0.44	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.35	GO:0072341	modified amino acid binding
0.34	GO:0046872	metal ion binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0051287	NAD binding
0.32	GO:0004386	helicase activity
0.31	GO:0005524	ATP binding

0.50	GO:0005829	cytosol
0.45	GO:0005840	ribosome
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.63

EC:2.1.1

GO:0008168

sp|O70489|PPT2_RAT
Lysosomal thioesterase PPT2
Search

PPT2

0.94	Palmitoyl-protein thioesterase 2

0.85	GO:0098734	macromolecule depalmitoylation
0.36	GO:0046949	fatty-acyl-CoA biosynthetic process

0.85	GO:0008474	palmitoyl-(protein) hydrolase activity
0.34	GO:0005509	calcium ion binding

0.40	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.35	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.1.2.22

GO:0008474

sp|O70490|ACSM2_RAT
Acyl-coenzyme A synthetase ACSM2, mitochondrial
Search

0.89	Acyl-coenzyme A synthetase ACSM2, mitochondrial

0.52	GO:0035383	thioester metabolic process
0.51	GO:0006633	fatty acid biosynthetic process
0.46	GO:0006732	coenzyme metabolic process
0.46	GO:1901568	fatty acid derivative metabolic process
0.44	GO:0055088	lipid homeostasis
0.42	GO:0006793	phosphorus metabolic process
0.41	GO:0006805	xenobiotic metabolic process
0.39	GO:0042593	glucose homeostasis
0.39	GO:0003008	system process
0.38	GO:0019605	butyrate metabolic process

0.63	GO:0003996	acyl-CoA ligase activity
0.63	GO:0047760	butyrate-CoA ligase activity
0.60	GO:0004321	fatty-acyl-CoA synthase activity
0.56	GO:0015645	fatty acid ligase activity
0.43	GO:0030554	adenyl nucleotide binding
0.42	GO:0032553	ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.39	GO:0032550	purine ribonucleoside binding

0.54	GO:0005759	mitochondrial matrix
0.38	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome

0.63

EC:6.2.1

GO:0003996

sp|O70511|ANK3_RAT
Ankyrin-3
Search

ANK3

0.49

Ankyrin-3

0.62	GO:0072660	maintenance of protein location in plasma membrane
0.61	GO:0007165	signal transduction
0.57	GO:0043001	Golgi to plasma membrane protein transport
0.55	GO:0007009	plasma membrane organization
0.55	GO:0000281	mitotic cytokinesis
0.53	GO:0071709	membrane assembly
0.50	GO:0007010	cytoskeleton organization
0.42	GO:1900827	positive regulation of membrane depolarization during cardiac muscle cell action potential
0.42	GO:0010650	positive regulation of cell communication by electrical coupling
0.41	GO:0071286	cellular response to magnesium ion

0.53	GO:0005200	structural constituent of cytoskeleton
0.48	GO:0030507	spectrin binding
0.40	GO:0044325	ion channel binding
0.39	GO:0045296	cadherin binding
0.39	GO:0030674	protein binding, bridging
0.31	GO:0019899	enzyme binding

0.60	GO:0043194	axon initial segment
0.58	GO:0009925	basal plasma membrane
0.57	GO:0016328	lateral plasma membrane
0.57	GO:0042383	sarcolemma
0.55	GO:0005923	bicellular tight junction
0.49	GO:0043034	costamere
0.41	GO:0033268	node of Ranvier
0.41	GO:0014731	spectrin-associated cytoskeleton
0.40	GO:0033270	paranode region of axon
0.40	GO:0014704	intercalated disc

sp|O70512|CISH_RAT
Cytokine-inducible SH2-containing protein (Fragment)
Search

CISH

0.97	Cytokine-inducible inhibitor of signalling type IV

0.66	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.53	GO:0046426	negative regulation of JAK-STAT cascade
0.50	GO:0046627	negative regulation of insulin receptor signaling pathway
0.48	GO:0006469	negative regulation of protein kinase activity
0.48	GO:0019221	cytokine-mediated signaling pathway
0.44	GO:0040008	regulation of growth
0.38	GO:0051128	regulation of cellular component organization
0.37	GO:0098761	cellular response to interleukin-7

0.49	GO:0004860	protein kinase inhibitor activity
0.41	GO:0008269	JAK pathway signal transduction adaptor activity
0.41	GO:0005159	insulin-like growth factor receptor binding
0.33	GO:0005131	growth hormone receptor binding

0.45	GO:0005622	intracellular
0.43	GO:0005886	plasma membrane

sp|O70513|LG3BP_RAT
Galectin-3-binding protein
Search

LGALS3BP

0.96	galectin-3-binding protein precursor

0.72	GO:0006898	receptor-mediated endocytosis
0.44	GO:0007155	cell adhesion
0.38	GO:0006968	cellular defense response
0.38	GO:0002576	platelet degranulation
0.37	GO:0006334	nucleosome assembly
0.34	GO:0007165	signal transduction
0.33	GO:0006508	proteolysis
0.32	GO:0055114	oxidation-reduction process

0.81	GO:0005044	scavenger receptor activity
0.37	GO:0017110	nucleoside-diphosphatase activity
0.37	GO:0005515	protein binding
0.36	GO:0005509	calcium ion binding
0.34	GO:0004252	serine-type endopeptidase activity
0.32	GO:0030246	carbohydrate binding
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.32	GO:0005507	copper ion binding

0.58	GO:0031012	extracellular matrix
0.57	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.39	GO:0031089	platelet dense granule lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.6.1.6

GO:0017110

sp|O70521|RGS19_RAT
Regulator of G-protein signaling 19
Search

RGS19

0.97	Regulator of G-protein signaling protein GAIP

0.70	GO:0043547	positive regulation of GTPase activity
0.53	GO:0009968	negative regulation of signal transduction
0.45	GO:0006914	autophagy
0.43	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.41	GO:0007264	small GTPase mediated signal transduction
0.40	GO:0007186	G-protein coupled receptor signaling pathway

0.70	GO:0005096	GTPase activator activity
0.54	GO:0001965	G-protein alpha-subunit binding

0.68	GO:0031410	cytoplasmic vesicle
0.57	GO:0005802	trans-Golgi network
0.52	GO:0005886	plasma membrane
0.52	GO:0005903	brush border
0.51	GO:0045121	membrane raft
0.42	GO:1905360	GTPase complex
0.41	GO:0000139	Golgi membrane
0.41	GO:0098562	cytoplasmic side of membrane
0.41	GO:0019898	extrinsic component of membrane
0.38	GO:0005634	nucleus

sp|O70531|S26A2_RAT
Sulfate transporter
Search

SLC26A2

0.55	Sulfate transporter

0.77	GO:0001503	ossification
0.74	GO:1902358	sulfate transmembrane transport
0.61	GO:0019532	oxalate transport
0.56	GO:1902476	chloride transmembrane transport
0.50	GO:0015701	bicarbonate transport
0.49	GO:0051453	regulation of intracellular pH
0.47	GO:0042391	regulation of membrane potential
0.45	GO:0036269	swimming behavior
0.45	GO:0032474	otolith morphogenesis
0.45	GO:0048884	neuromast development

0.77	GO:0008271	secondary active sulfate transmembrane transporter activity
0.62	GO:0019531	oxalate transmembrane transporter activity
0.60	GO:0015301	anion:anion antiporter activity
0.56	GO:0015108	chloride transmembrane transporter activity
0.50	GO:0015106	bicarbonate transmembrane transporter activity
0.46	GO:0005253	anion channel activity
0.33	GO:0008270	zinc ion binding

0.56	GO:0005887	integral component of plasma membrane
0.40	GO:0031528	microvillus membrane
0.38	GO:0016324	apical plasma membrane
0.37	GO:0070062	extracellular exosome
0.32	GO:0005622	intracellular

tr|O70534|O70534_RAT
Delta-like 1 homolog (Drosophila)
Search

DLK1

0.97	Delta like non-canonical Notch ligand 1

0.60	GO:0045746	negative regulation of Notch signaling pathway
0.43	GO:1905563	negative regulation of vascular endothelial cell proliferation
0.42	GO:0046852	positive regulation of bone remodeling
0.42	GO:0045124	regulation of bone resorption
0.41	GO:0030282	bone mineralization
0.41	GO:0045599	negative regulation of fat cell differentiation
0.41	GO:0030154	cell differentiation
0.41	GO:0035264	multicellular organism growth
0.41	GO:0048706	embryonic skeletal system development
0.40	GO:0032846	positive regulation of homeostatic process

0.69	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.32	GO:0004872	receptor activity
0.32	GO:0004222	metalloendopeptidase activity

0.52	GO:0005615	extracellular space
0.40	GO:0009897	external side of plasma membrane
0.32	GO:0016324	apical plasma membrane
0.31	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.32

GO:0004222

sp|O70535|LIFR_RAT
Leukemia inhibitory factor receptor
Search

LIFR

0.95	Leukemia inhibitory factor receptor alpha

0.78	GO:0019221	cytokine-mediated signaling pathway
0.54	GO:0048861	leukemia inhibitory factor signaling pathway
0.49	GO:0008284	positive regulation of cell proliferation
0.40	GO:0010656	negative regulation of muscle cell apoptotic process
0.39	GO:0031100	animal organ regeneration
0.38	GO:0048812	neuron projection morphogenesis
0.38	GO:0014070	response to organic cyclic compound
0.36	GO:0001959	regulation of cytokine-mediated signaling pathway

0.80	GO:0004896	cytokine receptor activity
0.54	GO:0005127	ciliary neurotrophic factor receptor binding
0.50	GO:0019838	growth factor binding
0.39	GO:0019955	cytokine binding
0.37	GO:0046982	protein heterodimerization activity

0.48	GO:0043235	receptor complex
0.45	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O70536|SOAT1_RAT
Sterol O-acyltransferase 1
Search

SOAT1

0.63	O-acyltransferase

0.72	GO:0034435	cholesterol esterification
0.66	GO:0042632	cholesterol homeostasis
0.59	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process
0.59	GO:0010878	cholesterol storage
0.58	GO:0034379	very-low-density lipoprotein particle assembly
0.58	GO:0010742	macrophage derived foam cell differentiation
0.57	GO:0008203	cholesterol metabolic process
0.56	GO:0033344	cholesterol efflux
0.35	GO:0034383	low-density lipoprotein particle clearance
0.32	GO:0006414	translational elongation

0.74	GO:0008374	O-acyltransferase activity
0.54	GO:0015485	cholesterol binding
0.53	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0005201	extracellular matrix structural constituent
0.33	GO:0005515	protein binding
0.32	GO:0003746	translation elongation factor activity

0.66	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005903	brush border
0.30	GO:0016021	integral component of membrane

0.74

EC:2.3.1

GO:0008374

sp|O70540|MADCA_RAT
Mucosal addressin cell adhesion molecule 1
Search

MADCAM1

0.97	Mucosal vascular addressin cell adhesion molecule 1 transcript variant 1

0.86	GO:2000403	positive regulation of lymphocyte migration
0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0050901	leukocyte tethering or rolling
0.61	GO:0034113	heterotypic cell-cell adhesion
0.55	GO:0043113	receptor clustering
0.47	GO:0030216	keratinocyte differentiation
0.46	GO:0007568	aging
0.37	GO:0030198	extracellular matrix organization
0.36	GO:0006955	immune response

0.87

GO:0098640

integrin binding involved in cell-matrix adhesion

0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O70593|SGTA_RAT
Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Search

SGTA

0.95	Kidney epithelial small glutamine rich tricopeptide-containing protein alpha

0.86	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process
0.86	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process
0.85	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.79	GO:0030433	ubiquitin-dependent ERAD pathway
0.37	GO:0006260	DNA replication
0.36	GO:0016032	viral process
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0006355	regulation of transcription, DNA-templated

0.86	GO:1904288	BAT3 complex binding
0.82	GO:0043621	protein self-association
0.41	GO:0042803	protein homodimerization activity
0.41	GO:0046982	protein heterodimerization activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003677	DNA binding

0.66	GO:0005829	cytosol
0.60	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|O70594|S22A5_RAT
Solute carrier family 22 member 5
Search

SLC22A5

0.89	LOW QUALITY PROTEIN: solute carrier family 22 member 5

0.66	GO:1902603	carnitine transmembrane transport
0.59	GO:0060731	positive regulation of intestinal epithelial structure maintenance
0.59	GO:0070715	sodium-dependent organic cation transport
0.58	GO:0052097	interspecies quorum sensing
0.57	GO:0009437	carnitine metabolic process
0.51	GO:0006641	triglyceride metabolic process
0.46	GO:0072337	modified amino acid transport
0.45	GO:0051701	interaction with host
0.45	GO:0015711	organic anion transport
0.40	GO:0006814	sodium ion transport

0.66	GO:0015226	carnitine transmembrane transporter activity
0.63	GO:0030165	PDZ domain binding
0.54	GO:0015491	cation:cation antiporter activity
0.46	GO:0008514	organic anion transmembrane transporter activity
0.40	GO:0015293	symporter activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008513	secondary active organic cation transmembrane transporter activity
0.36	GO:0015238	drug transmembrane transporter activity

0.61	GO:0016324	apical plasma membrane
0.55	GO:0031526	brush border membrane
0.44	GO:0005887	integral component of plasma membrane
0.43	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.35	GO:0031231	intrinsic component of peroxisomal membrane
0.35	GO:0016323	basolateral plasma membrane

sp|O70595|ABCB6_RAT
ATP-binding cassette sub-family B member 6, mitochondrial
Search

ABCB6

0.84	Dedicator of cytokinesis protein 1

0.55	GO:0043588	skin development
0.55	GO:0055085	transmembrane transport
0.53	GO:0007420	brain development
0.52	GO:0015886	heme transport
0.49	GO:0006779	porphyrin-containing compound biosynthetic process
0.44	GO:0097325	melanocyte proliferation
0.44	GO:0061072	iris morphogenesis
0.35	GO:0046686	response to cadmium ion
0.35	GO:0006879	cellular iron ion homeostasis
0.33	GO:0042908	xenobiotic transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0015232	heme transporter activity
0.50	GO:0015562	efflux transmembrane transporter activity
0.45	GO:0020037	heme binding
0.33	GO:0042910	xenobiotic transmembrane transporter activity
0.33	GO:0015238	drug transmembrane transporter activity

0.55	GO:0031307	integral component of mitochondrial outer membrane
0.51	GO:0005768	endosome
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005783	endoplasmic reticulum
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0044433	cytoplasmic vesicle part
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

sp|O70596|KCJ14_RAT
ATP-sensitive inward rectifier potassium channel 14
Search

0.82	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.58	GO:0014861	regulation of skeletal muscle contraction via regulation of action potential
0.58	GO:0090076	relaxation of skeletal muscle
0.57	GO:0055119	relaxation of cardiac muscle
0.56	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.55	GO:0086002	cardiac muscle cell action potential involved in contraction
0.55	GO:0086091	regulation of heart rate by cardiac conduction
0.54	GO:0051289	protein homotetramerization

0.84	GO:0005242	inward rectifier potassium channel activity
0.56	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
0.54	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.48	GO:0042802	identical protein binding
0.34	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.51	GO:0008076	voltage-gated potassium channel complex
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite
0.38	GO:0005790	smooth endoplasmic reticulum
0.38	GO:0030315	T-tubule
0.38	GO:0014704	intercalated disc
0.38	GO:0044309	neuron spine
0.37	GO:0005791	rough endoplasmic reticulum
0.37	GO:0098794	postsynapse
0.36	GO:0005794	Golgi apparatus

sp|O70597|PX11A_RAT
Peroxisomal membrane protein 11A
Search

PEX11A

0.96	Peroxisomal biogenesis factor 11 alpha

0.83	GO:0016559	peroxisome fission
0.72	GO:0044375	regulation of peroxisome size
0.67	GO:0050873	brown fat cell differentiation
0.50	GO:0007165	signal transduction
0.48	GO:0016557	peroxisome membrane biogenesis
0.37	GO:0019216	regulation of lipid metabolic process

0.59

GO:0042803

protein homodimerization activity

0.81	GO:0005779	integral component of peroxisomal membrane
0.49	GO:0043234	protein complex

sp|O70600|RSAD2_RAT
Radical S-adenosyl methionine domain-containing protein 2
Search

RSAD2

0.95	Radical S-adenosyl methionine domain-containing protein 2

0.77	GO:0051607	defense response to virus
0.61	GO:0034157	positive regulation of toll-like receptor 7 signaling pathway
0.60	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway
0.60	GO:2000553	positive regulation of T-helper 2 cell cytokine production
0.58	GO:0043367	CD4-positive, alpha-beta T cell differentiation
0.57	GO:0045071	negative regulation of viral genome replication
0.57	GO:0050709	negative regulation of protein secretion
0.42	GO:0045087	innate immune response
0.35	GO:0030278	regulation of ossification
0.35	GO:0001503	ossification

0.63	GO:0051536	iron-sulfur cluster binding
0.57	GO:0043621	protein self-association
0.36	GO:0046872	metal ion binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016874	ligase activity

0.82	GO:0005811	lipid droplet
0.71	GO:0005789	endoplasmic reticulum membrane
0.55	GO:0001650	fibrillar center
0.53	GO:0005741	mitochondrial outer membrane
0.45	GO:0019866	organelle inner membrane
0.34	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.33	EC:6	GO:0016874
0.34	KEGG:R03876	GO:0004842

sp|O70601|LAT_RAT
Linker for activation of T-cells family member 1
Search

LAT

0.97	Linker for activation of T cells

0.65	GO:0019722	calcium-mediated signaling
0.64	GO:0007265	Ras protein signal transduction
0.64	GO:0002260	lymphocyte homeostasis
0.62	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0045860	positive regulation of protein kinase activity
0.60	GO:0006954	inflammatory response
0.60	GO:0050863	regulation of T cell activation
0.60	GO:0009967	positive regulation of signal transduction
0.58	GO:0006955	immune response
0.46	GO:0002448	mast cell mediated immunity

0.66	GO:0005070	SH3/SH2 adaptor activity
0.61	GO:0019901	protein kinase binding
0.39	GO:0005057	signal transducer activity, downstream of receptor

0.69	GO:0001772	immunological synapse
0.60	GO:0008180	COP9 signalosome
0.58	GO:0005911	cell-cell junction
0.57	GO:0005794	Golgi apparatus
0.46	GO:0042629	mast cell granule
0.37	GO:0005887	integral component of plasma membrane

sp|O70608|SYCP2_RAT
Synaptonemal complex protein 2
Search

SYCP2

0.87	Synaptonemal complex protein 2

0.85	GO:0048808	male genitalia morphogenesis
0.84	GO:0007143	female meiotic nuclear division
0.83	GO:0007140	male meiotic nuclear division
0.80	GO:0009566	fertilization
0.76	GO:0060548	negative regulation of cell death
0.72	GO:0042981	regulation of apoptotic process
0.47	GO:0051301	cell division
0.43	GO:0007130	synaptonemal complex assembly

0.72	GO:0046982	protein heterodimerization activity
0.42	GO:0003677	DNA binding

0.85	GO:0000800	lateral element
0.46	GO:0005654	nucleoplasm
0.45	GO:0000780	condensed nuclear chromosome, centromeric region
0.34	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|O70609|O70609_RAT
Putative integral membrane transport protein
Search

0.96	Solute carrier family 22 (organic cation transporter), member 26

0.59	GO:0015747	urate transport
0.58	GO:0043252	sodium-independent organic anion transport
0.54	GO:0055085	transmembrane transport
0.48	GO:0015698	inorganic anion transport
0.46	GO:0015913	short-chain fatty acid import
0.43	GO:0009914	hormone transport
0.40	GO:0046415	urate metabolic process
0.39	GO:1901998	toxin transport
0.37	GO:0042493	response to drug

0.60	GO:0015143	urate transmembrane transporter activity
0.58	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.54	GO:0005452	inorganic anion exchanger activity
0.47	GO:0015636	short-chain fatty acid transmembrane transporter activity
0.43	GO:0015301	anion:anion antiporter activity
0.40	GO:0019534	toxin transmembrane transporter activity
0.40	GO:0030165	PDZ domain binding

0.47	GO:0005887	integral component of plasma membrane
0.45	GO:0098590	plasma membrane region
0.41	GO:0045177	apical part of cell

sp|O70610|CXD2_RAT
Gap junction delta-2 protein
Search

GJD2

0.64	Gap junction delta-2 protein (Fragment)

0.60	GO:0007154	cell communication
0.56	GO:0001508	action potential
0.53	GO:0007601	visual perception
0.45	GO:0023052	signaling
0.39	GO:0007416	synapse assembly
0.34	GO:0055085	transmembrane transport
0.34	GO:0006811	ion transport

0.38	GO:0005243	gap junction channel activity
0.35	GO:0022832	voltage-gated channel activity
0.35	GO:0022839	ion gated channel activity
0.35	GO:0008381	mechanosensitive ion channel activity
0.33	GO:0005515	protein binding

0.84	GO:0005922	connexin complex
0.30	GO:0031224	intrinsic component of membrane

sp|O70617|KCJ13_RAT
Inward rectifier potassium channel 13
Search

KCNJ13

0.97	Inward rectifier potassium channel 13

0.77	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.45	GO:0051876	pigment granule dispersal
0.44	GO:0051877	pigment granule aggregation in cell center
0.44	GO:0097324	melanocyte migration
0.43	GO:0030318	melanocyte differentiation
0.41	GO:0098660	inorganic ion transmembrane transport
0.34	GO:0046662	regulation of oviposition
0.33	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway

0.84	GO:0005242	inward rectifier potassium channel activity
0.31	GO:0008270	zinc ion binding
0.31	GO:0003676	nucleic acid binding

0.43	GO:0005887	integral component of plasma membrane
0.33	GO:0043025	neuronal cell body
0.33	GO:0043005	neuron projection

sp|O88177|PEX12_RAT
Peroxisome assembly protein 12
Search

PEX12

0.88	Peroxisome assembly protein 12

0.80	GO:0072662	protein localization to peroxisome
0.80	GO:0043574	peroxisomal transport
0.72	GO:0072594	establishment of protein localization to organelle
0.70	GO:0006605	protein targeting
0.55	GO:0017038	protein import
0.54	GO:0065002	intracellular protein transmembrane transport
0.49	GO:0006513	protein monoubiquitination
0.32	GO:0016310	phosphorylation

0.82	GO:0008022	protein C-terminus binding
0.62	GO:0008270	zinc ion binding
0.45	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016874	ligase activity
0.32	GO:0016301	kinase activity

0.79	GO:0005779	integral component of peroxisomal membrane
0.49	GO:1990429	peroxisomal importomer complex

0.33	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

sp|O88178|B3GT4_RAT
Beta-1,3-galactosyltransferase 4
Search

B3GALT4

0.44	Hexosyltransferase

0.74	GO:0006486	protein glycosylation
0.64	GO:0001574	ganglioside biosynthetic process
0.36	GO:0035235	ionotropic glutamate receptor signaling pathway
0.34	GO:0034220	ion transmembrane transport
0.33	GO:0008039	synaptic target recognition
0.32	GO:0007194	negative regulation of adenylate cyclase activity
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.81	GO:0008378	galactosyltransferase activity
0.54	GO:0008194	UDP-glycosyltransferase activity
0.36	GO:0030594	neurotransmitter receptor activity
0.36	GO:0008066	glutamate receptor activity
0.35	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding
0.32	GO:0008227	G-protein coupled amine receptor activity

0.72	GO:0000139	Golgi membrane
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.4.1

GO:0008378

sp|O88181|BARH2_RAT
BarH-like 2 homeobox protein
Search

BARHL2

0.97	BarH-class homeodomain transcription factor

0.61	GO:0001764	neuron migration
0.58	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0030516	regulation of axon extension
0.57	GO:0001709	cell fate determination
0.53	GO:0045727	positive regulation of translation
0.53	GO:0030182	neuron differentiation
0.48	GO:0030901	midbrain development
0.47	GO:0043524	negative regulation of neuron apoptotic process
0.46	GO:0007605	sensory perception of sound

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.59	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|O88182|FGF18_RAT
Fibroblast growth factor 18
Search

FGF18

0.61	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.58	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor
0.58	GO:0001957	intramembranous ossification
0.57	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.57	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.57	GO:2001028	positive regulation of endothelial cell chemotaxis
0.56	GO:0032332	positive regulation of chondrocyte differentiation
0.56	GO:0001958	endochondral ossification
0.56	GO:0002063	chondrocyte development

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.49	GO:0005730	nucleolus
0.32	GO:0005737	cytoplasm

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|O88201|CLC11_RAT
C-type lectin domain family 11 member A
Search

CLEC11A

0.97	Stem cell growth factor; lymphocyte secreted C-type lectin

0.64	GO:0008284	positive regulation of cell proliferation
0.62	GO:0010469	regulation of receptor activity
0.46	GO:0001503	ossification

0.64	GO:0008083	growth factor activity
0.63	GO:0030246	carbohydrate binding

0.55	GO:0005576	extracellular region
0.36	GO:0005737	cytoplasm

sp|O88202|LPP60_RAT
60 kDa lysophospholipase
Search

ASPG

0.42	Lysophospholipase

0.54	GO:0006520	cellular amino acid metabolic process
0.46	GO:0072329	monocarboxylic acid catabolic process
0.43	GO:1901565	organonitrogen compound catabolic process
0.41	GO:0043603	cellular amide metabolic process
0.38	GO:0016042	lipid catabolic process
0.35	GO:0007018	microtubule-based movement
0.35	GO:0006644	phospholipid metabolic process
0.34	GO:0046394	carboxylic acid biosynthetic process
0.34	GO:0006486	protein glycosylation

0.79	GO:0004067	asparaginase activity
0.42	GO:0004622	lysophospholipase activity
0.40	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.34	GO:0004576	oligosaccharyl transferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:3.5.1.1

GO:0004067

sp|O88204|LRP3_RAT
Low-density lipoprotein receptor-related protein 3
Search

LRP3

0.95	LDL receptor related protein 3

0.45	GO:0001764	neuron migration
0.43	GO:0031175	neuron projection development

0.39

GO:0005887

integral component of plasma membrane

tr|O88205|O88205_RAT
Cysteine-rich secretory protein 2
Search

0.92	Cysteine-Rich Secretory Protein B

0.39	GO:0098609	cell-cell adhesion
0.38	GO:0007283	spermatogenesis
0.37	GO:0009405	pathogenesis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0009566	fertilization
0.34	GO:0045087	innate immune response

0.37

GO:0090729

toxin activity

0.66	GO:0005576	extracellular region
0.44	GO:0042581	specific granule
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0030133	transport vesicle
0.30	GO:0016020	membrane

tr|O88206|O88206_RAT
Spongiotrophoblast specific protein
Search

TPBPA

0.97	Trophoblast-specific protein alpha

0.58	GO:0006508	proteolysis
0.49	GO:0007565	female pregnancy
0.45	GO:0007254	JNK cascade
0.43	GO:0071407	cellular response to organic cyclic compound
0.37	GO:0044257	cellular protein catabolic process

0.68	GO:0008234	cysteine-type peptidase activity
0.36	GO:0004175	endopeptidase activity

0.44	GO:0005615	extracellular space
0.38	GO:0005764	lysosome

0.68

GO:0008234

sp|O88267|ACOT1_RAT
Acyl-coenzyme A thioesterase 1
Search

0.54	Acyl-coenzyme A thioesterase 2, mitochondrial

0.73	GO:0035383	thioester metabolic process
0.64	GO:0032789	unsaturated monocarboxylic acid metabolic process
0.64	GO:0032788	saturated monocarboxylic acid metabolic process
0.63	GO:0006732	coenzyme metabolic process
0.61	GO:0000038	very long-chain fatty acid metabolic process
0.59	GO:0001676	long-chain fatty acid metabolic process
0.54	GO:0006793	phosphorus metabolic process
0.53	GO:0043649	dicarboxylic acid catabolic process
0.53	GO:0046459	short-chain fatty acid metabolic process
0.38	GO:0070849	response to epidermal growth factor

0.76	GO:0016790	thiolester hydrolase activity
0.52	GO:0005102	receptor binding
0.47	GO:0052689	carboxylic ester hydrolase activity

0.55	GO:0005777	peroxisome
0.42	GO:0005829	cytosol
0.41	GO:0005759	mitochondrial matrix
0.40	GO:0070062	extracellular exosome
0.37	GO:0031907	microbody lumen

0.76	EC:3.1.2	GO:0016790
0.47	KEGG:R00630	GO:0052689

sp|O88269|MRP6_RAT
Multidrug resistance-associated protein 6
Search

ABCC6

0.71	Multidrug resistance-associated protein 6

0.55	GO:0055085	transmembrane transport
0.38	GO:0030500	regulation of bone mineralization
0.38	GO:0071585	detoxification of cadmium ion
0.38	GO:0043009	chordate embryonic development
0.37	GO:0042493	response to drug
0.37	GO:0006820	anion transport
0.37	GO:0042908	xenobiotic transport
0.36	GO:0042939	tripeptide transport
0.35	GO:0072337	modified amino acid transport
0.35	GO:0007601	visual perception

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0034634	glutathione transmembrane transporter activity
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.36	GO:0015238	drug transmembrane transporter activity
0.35	GO:0046623	sphingolipid-translocating ATPase activity
0.34	GO:0004012	phospholipid-translocating ATPase activity

0.44	GO:0016323	basolateral plasma membrane
0.42	GO:0005634	nucleus
0.41	GO:0016328	lateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.39	GO:0005887	integral component of plasma membrane
0.35	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005856	cytoskeleton

0.34

EC:3.6.3.1

GO:0004012

sp|O88272|MMP23_RAT
Matrix metalloproteinase-23
Search

MMP23B

0.97	Matrix metalloproteinase-23

0.61	GO:0006508	proteolysis
0.47	GO:0000003	reproduction
0.40	GO:0001889	liver development
0.36	GO:0016567	protein ubiquitination
0.32	GO:0034769	basement membrane disassembly
0.32	GO:0006886	intracellular protein transport
0.32	GO:0016192	vesicle-mediated transport

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0016874	ligase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0031012	extracellular matrix
0.38	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0030131	clathrin adaptor complex
0.32	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.70	EC:3.4.24	GO:0004222
0.37	KEGG:R03876	GO:0004842

sp|O88275|PPARG_RAT
Peroxisome proliferator-activated receptor gamma
Search

PPARG

0.93	Peroxisome proliferator-activated receptor gamma

0.80	GO:0048511	rhythmic process
0.79	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0010742	macrophage derived foam cell differentiation
0.60	GO:0045713	low-density lipoprotein particle receptor biosynthetic process
0.59	GO:1905563	negative regulation of vascular endothelial cell proliferation
0.59	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.59	GO:0010887	negative regulation of cholesterol storage
0.59	GO:0060331	negative regulation of response to interferon-gamma
0.59	GO:0010871	negative regulation of receptor biosynthetic process

0.82	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.59	GO:0050692	DBD domain binding
0.59	GO:0050693	LBD domain binding
0.58	GO:0046965	retinoid X receptor binding
0.57	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.57	GO:0051393	alpha-actinin binding
0.56	GO:0043621	protein self-association

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.48	GO:0005737	cytoplasm
0.43	GO:0044446	intracellular organelle part
0.35	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

sp|O88277|FAT2_RAT
Protocadherin Fat 2
Search

FAT2

0.70	FAT atypical cadherin 2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.63	GO:0010631	epithelial cell migration
0.33	GO:0007163	establishment or maintenance of cell polarity
0.33	GO:0007015	actin filament organization

0.70

GO:0005509

calcium ion binding

0.63	GO:0005913	cell-cell adherens junction
0.56	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.36	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0030175	filopodium
0.34	GO:0030027	lamellipodium
0.30	GO:0044425	membrane part

sp|O88278|CELR3_RAT
Cadherin EGF LAG seven-pass G-type receptor 3
Search

CELSR3

0.88	Cadherin EGF LAG seven-pass G-type receptor 3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.71	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0036515	serotonergic neuron axon guidance
0.60	GO:0036514	dopaminergic neuron axon guidance
0.58	GO:0090175	regulation of establishment of planar polarity
0.58	GO:0007413	axonal fasciculation
0.57	GO:0001764	neuron migration
0.54	GO:0198738	cell-cell signaling by wnt
0.54	GO:0060271	cilium assembly

0.72	GO:0004930	G-protein coupled receptor activity
0.70	GO:0005509	calcium ion binding
0.45	GO:0008271	secondary active sulfate transmembrane transporter activity
0.35	GO:0005515	protein binding
0.32	GO:0016301	kinase activity

0.55	GO:0005886	plasma membrane
0.37	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|O88279|SLIT1_RAT
Slit homolog 1 protein
Search

0.66	Slit guidance ligand 1

0.55	GO:0048846	axon extension involved in axon guidance
0.54	GO:0050919	negative chemotaxis
0.53	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb
0.53	GO:0008045	motor neuron axon guidance
0.49	GO:0031290	retinal ganglion cell axon guidance
0.47	GO:0021891	olfactory bulb interneuron development
0.47	GO:0033563	dorsal/ventral axon guidance
0.45	GO:0007097	nuclear migration
0.43	GO:0050770	regulation of axonogenesis
0.43	GO:0021972	corticospinal neuron axon guidance through spinal cord

0.70	GO:0005509	calcium ion binding
0.56	GO:0048495	Roundabout binding
0.42	GO:0043237	laminin-1 binding
0.42	GO:0005095	GTPase inhibitor activity
0.41	GO:0043394	proteoglycan binding
0.40	GO:0008201	heparin binding
0.39	GO:0042803	protein homodimerization activity

0.50	GO:0005576	extracellular region
0.35	GO:0005622	intracellular
0.32	GO:0005886	plasma membrane

sp|O88280|SLIT3_RAT
Slit homolog 3 protein
Search

SLIT3

0.86	Slit guidance ligand 3

0.55	GO:0030308	negative regulation of cell growth
0.53	GO:0007409	axonogenesis
0.53	GO:0061364	apoptotic process involved in luteolysis
0.53	GO:0051414	response to cortisol
0.53	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.52	GO:1902284	neuron projection extension involved in neuron projection guidance
0.51	GO:0050771	negative regulation of axonogenesis
0.51	GO:0050919	negative chemotaxis
0.51	GO:0035385	Roundabout signaling pathway
0.51	GO:0021954	central nervous system neuron development

0.70	GO:0005509	calcium ion binding
0.53	GO:0048495	Roundabout binding
0.44	GO:0043237	laminin-1 binding
0.44	GO:0005095	GTPase inhibitor activity
0.43	GO:0043394	proteoglycan binding
0.42	GO:0008201	heparin binding
0.40	GO:0042803	protein homodimerization activity
0.36	GO:0004963	follicle-stimulating hormone receptor activity
0.32	GO:0004594	pantothenate kinase activity
0.31	GO:0030554	adenyl nucleotide binding

0.54	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm
0.34	GO:0009986	cell surface
0.34	GO:0031982	vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.32

EC:2.7.1.33

GO:0004594

sp|O88281|MEGF6_RAT
Multiple epidermal growth factor-like domains protein 6
Search

MEGF6

0.74	Multiple EGF like domains 6

0.40

GO:0001558

regulation of cell growth

0.69	GO:0005509	calcium ion binding
0.41	GO:0005520	insulin-like growth factor binding

0.40	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|O88298|RHD_RAT
Blood group Rh(D) polypeptide
Search

RHCE

0.95	Rh blood group Rhce antigen variant

0.77	GO:0072488	ammonium transmembrane transport
0.42	GO:0015695	organic cation transport
0.39	GO:0060586	multicellular organismal iron ion homeostasis
0.38	GO:0048821	erythrocyte development

0.77

GO:0008519

ammonium transmembrane transporter activity

0.40

GO:0005887

integral component of plasma membrane

sp|O88302|GNA15_RAT
Guanine nucleotide-binding protein subunit alpha-15
Search

GNA15

0.87	Guanine nucleotide binding protein, q polypeptide

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.48	GO:0045634	regulation of melanocyte differentiation
0.47	GO:0001508	action potential
0.46	GO:0007603	phototransduction, visible light
0.46	GO:0071467	cellular response to pH
0.46	GO:0009649	entrainment of circadian clock
0.46	GO:0048066	developmental pigmentation
0.46	GO:0095500	acetylcholine receptor signaling pathway
0.44	GO:0001501	skeletal system development

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.78	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.36	GO:0046872	metal ion binding

0.50	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0001750	photoreceptor outer segment
0.44	GO:0098797	plasma membrane protein complex
0.36	GO:0005765	lysosomal membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.36

EC:3.1.4.39

GO:0047391

tr|O88321|O88321_RAT
Antisecretory factor
Search

PSMD4

0.89	26S proteasome non-ATPase regulatory subunit 4

0.66	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0043248	proteasome assembly
0.43	GO:0010498	proteasomal protein catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation
0.36	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.45	GO:0031593	polyubiquitin modification-dependent protein binding
0.37	GO:0042802	identical protein binding
0.37	GO:0008134	transcription factor binding
0.34	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.75	GO:0008540	proteasome regulatory particle, base subcomplex
0.47	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome

sp|O88339|EPN1_RAT
Epsin-1
Search

EPN1

0.77	Phosphatidylinositol-binding clathrin assembly protein

0.71	GO:1903671	negative regulation of sprouting angiogenesis
0.64	GO:0007565	female pregnancy
0.62	GO:0006897	endocytosis
0.62	GO:0001701	in utero embryonic development
0.62	GO:0007219	Notch signaling pathway
0.60	GO:0048568	embryonic organ development
0.48	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.47	GO:0045747	positive regulation of Notch signaling pathway
0.44	GO:1905443	regulation of clathrin coat assembly
0.41	GO:0031334	positive regulation of protein complex assembly

0.46	GO:0045296	cadherin binding
0.43	GO:0008289	lipid binding
0.42	GO:0035615	clathrin adaptor activity
0.42	GO:0044325	ion channel binding
0.39	GO:0008134	transcription factor binding
0.34	GO:0003723	RNA binding

0.69	GO:0030128	clathrin coat of endocytic vesicle
0.56	GO:0005829	cytosol
0.46	GO:0005905	clathrin-coated pit
0.45	GO:0098890	extrinsic component of postsynaptic membrane
0.45	GO:0098888	extrinsic component of presynaptic membrane
0.42	GO:0043195	terminal bouton
0.42	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

sp|O88350|RBBP9_RAT
Putative hydrolase RBBP9
Search

RBBP9

0.97	Retinoblastoma binding protein 9

0.40	GO:0042127	regulation of cell proliferation
0.35	GO:0009312	oligosaccharide biosynthetic process
0.34	GO:0006446	regulation of translational initiation
0.34	GO:0006413	translational initiation
0.32	GO:0006429	leucyl-tRNA aminoacylation
0.32	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.51	GO:0016787	hydrolase activity
0.35	GO:0005515	protein binding
0.34	GO:0043022	ribosome binding
0.34	GO:0003743	translation initiation factor activity
0.32	GO:0004823	leucine-tRNA ligase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005654	nucleoplasm
0.38	GO:0070062	extracellular exosome
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:1905369	endopeptidase complex

0.51	EC:3	GO:0016787
0.32	KEGG:R03657	GO:0004823

sp|O88368|MITF_RAT
Microphthalmia-associated transcription factor (Fragment)
Search

0.53	Microphthalmia-associated transcription factor (Fragment)

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.54	GO:0030318	melanocyte differentiation
0.52	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process
0.50	GO:0030316	osteoclast differentiation
0.50	GO:0045670	regulation of osteoclast differentiation
0.50	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.50	GO:0046849	bone remodeling
0.48	GO:0043010	camera-type eye development
0.47	GO:0045165	cell fate commitment
0.46	GO:0006366	transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0070888	E-box binding
0.46	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

sp|O88370|PI42C_RAT
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Search

PIP4K2C

0.95	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.59	GO:2000786	positive regulation of autophagosome assembly
0.39	GO:0035855	megakaryocyte development
0.37	GO:0006661	phosphatidylinositol biosynthetic process
0.37	GO:0007018	microtubule-based movement
0.37	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.34	GO:0001558	regulation of cell growth

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042802	identical protein binding
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.34	GO:0005520	insulin-like growth factor binding

0.57	GO:0005776	autophagosome
0.37	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005654	nucleoplasm
0.32	GO:0005886	plasma membrane

0.82

GO:0016307

sp|O88377|PI42B_RAT
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Search

PIP4K2B

0.93	Phosphatidylinositol-4-phosphate 5-kinase type II beta

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.61	GO:2000786	positive regulation of autophagosome assembly
0.47	GO:0035855	megakaryocyte development
0.36	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.35	GO:0006661	phosphatidylinositol biosynthetic process
0.34	GO:0007166	cell surface receptor signaling pathway

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.58	GO:0005776	autophagosome
0.47	GO:0005654	nucleoplasm
0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol

0.82

GO:0016307

sp|O88382|MAGI2_RAT
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Search

MAGI2

0.93	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

0.58	GO:0032926	negative regulation of activin receptor signaling pathway
0.57	GO:0007165	signal transduction
0.57	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.56	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.56	GO:2000809	positive regulation of synaptic vesicle clustering
0.56	GO:0002092	positive regulation of receptor internalization
0.55	GO:0051898	negative regulation of protein kinase B signaling
0.49	GO:0072015	glomerular visceral epithelial cell development
0.49	GO:0016310	phosphorylation
0.49	GO:0071850	mitotic cell cycle arrest

0.76	GO:0032947	protein complex scaffold activity
0.60	GO:0070699	type II activin receptor binding
0.58	GO:0031697	beta-1 adrenergic receptor binding
0.56	GO:0046332	SMAD binding
0.53	GO:0019902	phosphatase binding
0.51	GO:0016301	kinase activity
0.46	GO:0004871	signal transducer activity
0.36	GO:0019894	kinesin binding
0.35	GO:0032403	protein complex binding
0.32	GO:0008270	zinc ion binding

0.76	GO:0005923	bicellular tight junction
0.51	GO:0097458	neuron part
0.50	GO:0036057	slit diaphragm
0.49	GO:0120038	plasma membrane bounded cell projection part
0.47	GO:0032279	asymmetric synapse
0.47	GO:0099572	postsynaptic specialization
0.46	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.39	GO:0005770	late endosome

sp|O88387|FGD4_RAT
FYVE, RhoGEF and PH domain-containing protein 4
Search

FGD4

0.96	FYVE, RhoGEF and PH domain-containing protein 4

0.76	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.50	GO:0030035	microspike assembly
0.48	GO:0030032	lamellipodium assembly
0.38	GO:0007254	JNK cascade
0.37	GO:0046330	positive regulation of JNK cascade
0.36	GO:0046847	filopodium assembly
0.35	GO:0008360	regulation of cell shape
0.35	GO:0043065	positive regulation of apoptotic process
0.34	GO:0030036	actin cytoskeleton organization

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.53	GO:0046872	metal ion binding
0.37	GO:0003779	actin binding
0.35	GO:0032403	protein complex binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0030175	filopodium
0.47	GO:0030027	lamellipodium
0.38	GO:0005622	intracellular
0.35	GO:0001726	ruffle
0.35	GO:0043228	non-membrane-bounded organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0043227	membrane-bounded organelle

sp|O88397|SO1A5_RAT
Solute carrier organic anion transporter family member 1A5
Search

SLCO1A2

0.62	Solute carrier organic anion transporter family member

0.58	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0071702	organic substance transport
0.42	GO:0010876	lipid localization
0.42	GO:0035634	response to stilbenoid
0.41	GO:0031100	animal organ regeneration
0.40	GO:0070327	thyroid hormone transport
0.40	GO:0033574	response to testosterone
0.39	GO:0050892	intestinal absorption
0.38	GO:0008206	bile acid metabolic process

0.56

GO:0005215

transporter activity

0.55	GO:0005886	plasma membrane
0.38	GO:0005903	brush border
0.37	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

sp|O88406|SMAD7_RAT
Mothers against decapentaplegic homolog 7
Search

SMAD7

0.65	Mothers against decapentaplegic homolog

0.76	GO:0007179	transforming growth factor beta receptor signaling pathway
0.60	GO:0010944	negative regulation of transcription by competitive promoter binding
0.60	GO:0034616	response to laminar fluid shear stress
0.59	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.59	GO:2000320	negative regulation of T-helper 17 cell differentiation
0.59	GO:0002725	negative regulation of T cell cytokine production
0.59	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.58	GO:0032925	regulation of activin receptor signaling pathway
0.58	GO:0051444	negative regulation of ubiquitin-protein transferase activity
0.58	GO:0060389	pathway-restricted SMAD protein phosphorylation

0.61	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
0.60	GO:0048185	activin binding
0.60	GO:0070411	I-SMAD binding
0.59	GO:0034713	type I transforming growth factor beta receptor binding
0.57	GO:0003700	DNA binding transcription factor activity
0.56	GO:0008013	beta-catenin binding
0.55	GO:0005518	collagen binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0046872	metal ion binding

0.69	GO:0005667	transcription factor complex
0.58	GO:0016342	catenin complex
0.57	GO:0005634	nucleus
0.56	GO:0005913	cell-cell adherens junction
0.53	GO:0005813	centrosome
0.48	GO:0005829	cytosol
0.48	GO:0070013	intracellular organelle lumen
0.37	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

sp|O88407|LFG2_RAT
Protein lifeguard 2
Search

FAIM2

0.97	Fas apoptotic inhibitory molecule 2

0.59	GO:0021681	cerebellar granular layer development
0.59	GO:0021702	cerebellar Purkinje cell differentiation
0.59	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.58	GO:0002931	response to ischemia
0.56	GO:0043523	regulation of neuron apoptotic process
0.56	GO:1901215	negative regulation of neuron death
0.40	GO:0006915	apoptotic process
0.36	GO:1902045	negative regulation of Fas signaling pathway
0.36	GO:1903077	negative regulation of protein localization to plasma membrane
0.34	GO:0015689	molybdate ion transport

0.36	GO:0005123	death receptor binding
0.34	GO:0015098	molybdate ion transmembrane transporter activity

0.55	GO:0045121	membrane raft
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005783	endoplasmic reticulum
0.40	GO:0045211	postsynaptic membrane
0.39	GO:0030054	cell junction
0.35	GO:0005765	lysosomal membrane
0.35	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

sp|O88419|B4GT6_RAT
Beta-1,4-galactosyltransferase 6
Search

B4GALT6

0.97	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5

0.61	GO:0001572	lactosylceramide biosynthetic process
0.60	GO:0005975	carbohydrate metabolic process
0.39	GO:0009101	glycoprotein biosynthetic process
0.38	GO:0043413	macromolecule glycosylation
0.37	GO:0048840	otolith development
0.37	GO:0018146	keratan sulfate biosynthetic process
0.37	GO:0009950	dorsal/ventral axis specification
0.37	GO:0030513	positive regulation of BMP signaling pathway
0.37	GO:0006029	proteoglycan metabolic process
0.35	GO:0036211	protein modification process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0046872	metal ion binding

0.39	GO:0032580	Golgi cisterna membrane
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:2.4

GO:0016757

sp|O88420|SCN8A_RAT
Sodium channel protein type 8 subunit alpha
Search

SCN8A

0.66	Sodium voltage-gated channel alpha subunit 8

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.48	GO:0019228	neuronal action potential
0.48	GO:0086010	membrane depolarization during action potential
0.38	GO:0007626	locomotory behavior
0.38	GO:0048731	system development
0.37	GO:0050905	neuromuscular process
0.37	GO:0030534	adult behavior
0.37	GO:0007605	sensory perception of sound
0.37	GO:0061061	muscle structure development

0.84	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.39	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.35	GO:0031402	sodium ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.40	GO:0033268	node of Ranvier
0.39	GO:0030018	Z disc
0.38	GO:0043194	axon initial segment
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.34	GO:0031410	cytoplasmic vesicle

sp|O88422|GALT5_RAT
Polypeptide N-acetylgalactosaminyltransferase 5
Search

GALNT5

0.53	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0006486	protein glycosylation
0.35	GO:0006024	glycosaminoglycan biosynthetic process
0.34	GO:0018210	peptidyl-threonine modification
0.33	GO:0009226	nucleotide-sugar biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.68	GO:0030246	carbohydrate binding
0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.46	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0046872	metal ion binding
0.34	GO:0005112	Notch binding
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0004497	monooxygenase activity
0.32	GO:0048037	cofactor binding
0.32	GO:0046906	tetrapyrrole binding

0.72	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:2.4

GO:0016757

sp|O88426|NDK6_RAT
Nucleoside diphosphate kinase 6 (Fragment)
Search

NME6

0.45	Nucleoside diphosphate kinase

0.77	GO:0006228	UTP biosynthetic process
0.77	GO:0006183	GTP biosynthetic process
0.74	GO:0046036	CTP metabolic process
0.69	GO:0006165	nucleoside diphosphate phosphorylation
0.39	GO:0030308	negative regulation of cell growth
0.38	GO:0045839	negative regulation of mitotic nuclear division
0.36	GO:0015949	nucleobase-containing small molecule interconversion
0.35	GO:0006915	apoptotic process
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.78	GO:0004550	nucleoside diphosphate kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0046872	metal ion binding
0.33	GO:0004519	endonuclease activity

0.45	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol

0.78

EC:2.7.4.6

GO:0004550

sp|O88436|PAX4_RAT
Paired box protein Pax-4
Search

PAX4

0.97	Paired box protein Pax-4

0.71	GO:0031016	pancreas development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0045597	positive regulation of cell differentiation
0.52	GO:0051253	negative regulation of RNA metabolic process
0.52	GO:0010558	negative regulation of macromolecule biosynthetic process
0.52	GO:0031327	negative regulation of cellular biosynthetic process
0.48	GO:0060041	retina development in camera-type eye

0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.56	GO:0035326	enhancer binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.46	GO:0070410	co-SMAD binding
0.46	GO:0071837	HMG box domain binding
0.45	GO:0070412	R-SMAD binding
0.45	GO:0035035	histone acetyltransferase binding
0.44	GO:0001047	core promoter binding

0.61	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0000785	chromatin
0.40	GO:0005829	cytosol
0.36	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.35

GO:0004842

sp|O88446|S22A3_RAT
Solute carrier family 22 member 3
Search

SLC22A3

0.94	Organic cation transporter 3

0.60	GO:0051615	histamine uptake
0.58	GO:0015844	monoamine transport
0.56	GO:0032098	regulation of appetite
0.55	GO:0055085	transmembrane transport
0.55	GO:0015697	quaternary ammonium group transport
0.47	GO:0015850	organic hydroxy compound transport
0.44	GO:0015893	drug transport
0.43	GO:0015711	organic anion transport
0.40	GO:1901998	toxin transport
0.35	GO:1901374	acetate ester transport

0.58	GO:0015651	quaternary ammonium group transmembrane transporter activity
0.52	GO:0005329	dopamine transmembrane transporter activity
0.44	GO:0008514	organic anion transmembrane transporter activity
0.40	GO:0019534	toxin transmembrane transporter activity
0.35	GO:0008513	secondary active organic cation transmembrane transporter activity
0.35	GO:0005333	norepinephrine transmembrane transporter activity
0.35	GO:0005277	acetylcholine transmembrane transporter activity
0.35	GO:0005515	protein binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.44

GO:0005887

integral component of plasma membrane

sp|O88450|DEAF1_RAT
Deformed epidermal autoregulatory factor 1 homolog
Search

DEAF1

0.89	DEAF1 transcription factor

0.73	GO:0033599	regulation of mammary gland epithelial cell proliferation
0.73	GO:0001662	behavioral fear response
0.72	GO:0008542	visual learning
0.70	GO:0001843	neural tube closure
0.69	GO:0048706	embryonic skeletal system development
0.65	GO:0000122	negative regulation of transcription by RNA polymerase II
0.63	GO:0006366	transcription by RNA polymerase II
0.61	GO:0045893	positive regulation of transcription, DNA-templated

0.68	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.65	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.69	GO:0001650	fibrillar center
0.63	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|O88453|SAFB1_RAT
Scaffold attachment factor B1
Search

0.74	GO:0050684	regulation of mRNA processing
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0030520	intracellular estrogen receptor signaling pathway
0.48	GO:0040007	growth
0.47	GO:0042445	hormone metabolic process
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.46	GO:0060765	regulation of androgen receptor signaling pathway
0.46	GO:0010628	positive regulation of gene expression
0.45	GO:0060008	Sertoli cell differentiation

0.59	GO:0003723	RNA binding
0.50	GO:0001047	core promoter binding
0.48	GO:0003682	chromatin binding
0.46	GO:0003690	double-stranded DNA binding
0.43	GO:0043565	sequence-specific DNA binding
0.42	GO:0042802	identical protein binding
0.32	GO:0003700	DNA binding transcription factor activity

0.48	GO:0005654	nucleoplasm
0.34	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm

sp|O88457|SCNBA_RAT
Sodium channel protein type 11 subunit alpha
Search

SCN11A

0.53	Sodium channel protein type 4 subunit alpha A

0.77	GO:0035725	sodium ion transmembrane transport
0.77	GO:0034765	regulation of ion transmembrane transport
0.66	GO:0051930	regulation of sensory perception of pain
0.56	GO:0019228	neuronal action potential
0.56	GO:0086010	membrane depolarization during action potential
0.51	GO:0019233	sensory perception of pain
0.42	GO:0086043	bundle of His cell action potential
0.42	GO:0086016	AV node cell action potential
0.42	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.41	GO:0055117	regulation of cardiac muscle contraction

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.72	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.41	GO:0044325	ion channel binding
0.34	GO:0005509	calcium ion binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.69	GO:0044299	C-fiber
0.41	GO:0070062	extracellular exosome
0.35	GO:0071439	clathrin complex

sp|O88480|CABIN_RAT
Calcineurin-binding protein cabin-1
Search

CABIN1

0.91	Calcineurin binding protein 1

0.85	GO:0006336	DNA replication-independent nucleosome assembly
0.43	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.38	GO:0007165	signal transduction

0.52	GO:0031491	nucleosome binding
0.44	GO:0004864	protein phosphatase inhibitor activity

0.66	GO:0016235	aggresome
0.55	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol

sp|O88483|PDP1_RAT
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
Search

PDP1

0.89	Pyruvate dehydrogenase acetyl-transferring-phosphatase 1

0.72	GO:0006470	protein dephosphorylation
0.36	GO:0010826	negative regulation of centrosome duplication
0.36	GO:0060271	cilium assembly
0.35	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.34	GO:0043085	positive regulation of catalytic activity

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.54	GO:0046872	metal ion binding
0.41	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity
0.34	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.38	GO:0005759	mitochondrial matrix
0.36	GO:0036038	MKS complex
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:3.1.3.43

GO:0004741

sp|O88484|PDP2_RAT
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial
Search

PDP2

0.97	Pyruvate dehydrogenase acetyl-transferring-phosphatase 2

0.72	GO:0006470	protein dephosphorylation
0.37	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.36	GO:0009758	carbohydrate utilization
0.33	GO:0006730	one-carbon metabolic process

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.53	GO:0046872	metal ion binding
0.45	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity
0.34	GO:0004089	carbonate dehydratase activity
0.33	GO:0005515	protein binding

0.45	GO:0005739	mitochondrion
0.37	GO:0045253	pyruvate dehydrogenase (lipoamide) phosphatase complex
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

0.45

EC:3.1.3.43

GO:0004741

sp|O88488|PTPRQ_RAT
Phosphatidylinositol phosphatase PTPRQ
Search

0.64	Phosphatidylinositol phosphatase PTPRQ

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.54	GO:0060116	vestibular receptor cell morphogenesis
0.52	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.51	GO:0050885	neuromuscular process controlling balance
0.50	GO:0002244	hematopoietic progenitor cell differentiation
0.35	GO:0045598	regulation of fat cell differentiation
0.34	GO:0046373	L-arabinose metabolic process
0.33	GO:0000272	polysaccharide catabolic process

0.74	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0046556	alpha-L-arabinofuranosidase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0030246	carbohydrate binding

0.50	GO:0032421	stereocilium bundle
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0071944	cell periphery

0.74

GO:0004725

sp|O88496|VKGC_RAT
Vitamin K-dependent gamma-carboxylase
Search

GGCX

0.79	Vitamin K-dependent gamma-glutamyl carboxylase

0.85	GO:0017187	peptidyl-glutamic acid carboxylation
0.37	GO:1904016	response to Thyroglobulin triiodothyronine
0.37	GO:0032571	response to vitamin K
0.37	GO:0060437	lung growth
0.36	GO:0010042	response to manganese ion
0.36	GO:0071107	response to parathyroid hormone
0.36	GO:0033280	response to vitamin D
0.36	GO:0071548	response to dexamethasone
0.35	GO:0070482	response to oxygen levels
0.35	GO:0007596	blood coagulation

0.85	GO:0008488	gamma-glutamyl carboxylase activity
0.35	GO:0042277	peptide binding
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.34	GO:0019842	vitamin binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004478	methionine adenosyltransferase activity
0.32	GO:0046872	metal ion binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:4.1.1

GO:0008488

sp|O88498|B2L11_RAT
Bcl-2-like protein 11
Search

sp|O88501|CAN6_RAT
Calpain-6
Search

CAPN6

0.93	Calpamodulin

0.67	GO:0051493	regulation of cytoskeleton organization
0.61	GO:0006508	proteolysis
0.56	GO:0001578	microtubule bundle formation
0.35	GO:0007165	signal transduction
0.34	GO:0007608	sensory perception of smell
0.33	GO:0043066	negative regulation of apoptotic process
0.32	GO:0007586	digestion

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.51	GO:0008017	microtubule binding
0.36	GO:0005509	calcium ion binding
0.33	GO:0004871	signal transducer activity

0.55	GO:0005876	spindle microtubule
0.54	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005829	cytosol
0.37	GO:0009986	cell surface

sp|O88506|STK39_RAT
STE20/SPS1-related proline-alanine-rich protein kinase
Search

STK39

0.96	Serine threonine kinase 39

0.60	GO:0006468	protein phosphorylation
0.40	GO:0035556	intracellular signal transduction
0.40	GO:0032147	activation of protein kinase activity
0.39	GO:0007346	regulation of mitotic cell cycle
0.39	GO:0042981	regulation of apoptotic process
0.37	GO:0033554	cellular response to stress

0.63	GO:0004674	protein serine/threonine kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0005057	signal transducer activity, downstream of receptor

0.35

GO:0005622

intracellular

0.63

GO:0004674

sp|O88514|DEFB4_RAT
Beta-defensin 4
Search

0.61	Lingual antimicrobial peptide

0.75	GO:0042742	defense response to bacterium
0.48	GO:0006935	chemotaxis
0.48	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.46	GO:0031640	killing of cells of other organism
0.40	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.40	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.39	GO:0019933	cAMP-mediated signaling
0.37	GO:0045087	innate immune response
0.37	GO:0016477	cell migration
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.59	GO:0031731	CCR6 chemokine receptor binding
0.39	GO:0042056	chemoattractant activity
0.37	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.41	GO:0005796	Golgi lumen
0.40	GO:0097225	sperm midpiece
0.37	GO:0019898	extrinsic component of membrane
0.37	GO:0031982	vesicle

tr|O88550|O88550_RAT
Caspase 7
Search

CASP7

0.97	'Caspase 7, apoptosis-related cysteine peptidase'

0.61	GO:0006508	proteolysis
0.60	GO:0097194	execution phase of apoptosis
0.58	GO:0051402	neuron apoptotic process
0.55	GO:0009411	response to UV
0.55	GO:0007507	heart development
0.51	GO:0051604	protein maturation
0.46	GO:0072733	response to staurosporine
0.44	GO:0071312	cellular response to alkaloid
0.43	GO:0071242	cellular response to ammonium ion
0.43	GO:0030216	keratinocyte differentiation

0.75	GO:0004197	cysteine-type endopeptidase activity
0.50	GO:0004190	aspartic-type endopeptidase activity
0.40	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.37	GO:0005515	protein binding
0.35	GO:0016005	phospholipase A2 activator activity
0.34	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0044877	macromolecular complex binding

0.41	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.35	GO:0097179	protease inhibitor complex
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0031264	death-inducing signaling complex
0.34	GO:0044446	intracellular organelle part
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0043197	dendritic spine
0.34	GO:0014069	postsynaptic density

0.75

EC:3.4.22

GO:0004197

sp|O88553|ZFP37_RAT
Zinc finger protein 37
Search

ZFP37

0.70	Zinc finger protein 37

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:0032502	developmental process
0.37	GO:0032501	multicellular organismal process
0.37	GO:0008283	cell proliferation
0.37	GO:0019953	sexual reproduction

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle

sp|O88563|MRP3_RAT
Canalicular multispecific organic anion transporter 2
Search

ABCC3

0.85	Canalicular multispecific organic anion transporter 2

0.55	GO:0055085	transmembrane transport
0.46	GO:0015722	canalicular bile acid transport
0.42	GO:0042908	xenobiotic transport
0.40	GO:0015893	drug transport
0.38	GO:0032355	response to estradiol
0.38	GO:0032496	response to lipopolysaccharide
0.37	GO:0010243	response to organonitrogen compound
0.36	GO:0099133	ATP hydrolysis coupled anion transmembrane transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042910	xenobiotic transmembrane transporter activity
0.42	GO:0015125	bile acid transmembrane transporter activity
0.40	GO:0015238	drug transmembrane transporter activity

0.43	GO:0016323	basolateral plasma membrane
0.39	GO:0005887	integral component of plasma membrane

sp|O88582|SOCS2_RAT
Suppressor of cytokine signaling 2
Search

SOCS2

0.97	Suppressor of cytokine-signaling 2

0.85	GO:0046426	negative regulation of JAK-STAT cascade
0.77	GO:0001558	regulation of cell growth
0.66	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0040015	negative regulation of multicellular organism growth
0.60	GO:0060396	growth hormone receptor signaling pathway
0.59	GO:0032355	response to estradiol
0.59	GO:0061377	mammary gland lobule development
0.58	GO:0007595	lactation
0.57	GO:0045666	positive regulation of neuron differentiation

0.85	GO:0008269	JAK pathway signal transduction adaptor activity
0.85	GO:0005159	insulin-like growth factor receptor binding
0.59	GO:0005131	growth hormone receptor binding
0.48	GO:0019210	kinase inhibitor activity
0.47	GO:0019887	protein kinase regulator activity
0.35	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0019901	protein kinase binding
0.35	GO:0070513	death domain binding
0.32	GO:0003779	actin binding

0.49	GO:0005737	cytoplasm
0.35	GO:0035770	ribonucleoprotein granule
0.34	GO:0005654	nucleoplasm

sp|O88583|SOCS3_RAT
Suppressor of cytokine signaling 3
Search

SOCS3

0.97	Suppressor of cytokine signaling 3

0.85	GO:0007259	JAK-STAT cascade
0.78	GO:0043066	negative regulation of apoptotic process
0.68	GO:0016567	protein ubiquitination
0.64	GO:0060708	spongiotrophoblast differentiation
0.64	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.64	GO:0046627	negative regulation of insulin receptor signaling pathway
0.63	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.63	GO:0060707	trophoblast giant cell differentiation
0.62	GO:0060674	placenta blood vessel development
0.61	GO:0050728	negative regulation of inflammatory response

0.62	GO:0001784	phosphotyrosine residue binding
0.49	GO:0004860	protein kinase inhibitor activity
0.36	GO:0008269	JAK pathway signal transduction adaptor activity
0.36	GO:0005159	insulin-like growth factor receptor binding

0.45

GO:0005622

intracellular

sp|O88588|PACS1_RAT
Phosphofurin acidic cluster sorting protein 1
Search

PACS1

0.95	Phosphofurin acidic cluster sorting protein 1

0.77	GO:0000042	protein targeting to Golgi
0.77	GO:0072659	protein localization to plasma membrane
0.43	GO:0034497	protein localization to phagophore assembly site
0.40	GO:0032092	positive regulation of protein binding
0.38	GO:0050690	regulation of defense response to virus by virus

0.83

GO:0044325

ion channel binding

0.71	GO:0030137	COPI-coated vesicle
0.44	GO:0012505	endomembrane system
0.40	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|O88599|MYBPH_RAT
Myosin-binding protein H
Search

MYBPH

0.97	Myosin binding protein H like

0.80	GO:0071688	striated muscle myosin thick filament assembly
0.77	GO:0045214	sarcomere organization
0.75	GO:0006941	striated muscle contraction
0.67	GO:0007015	actin filament organization
0.52	GO:0060537	muscle tissue development
0.48	GO:0007517	muscle organ development
0.46	GO:0007155	cell adhesion
0.45	GO:0014904	myotube cell development
0.45	GO:0048747	muscle fiber development
0.43	GO:0003208	cardiac ventricle morphogenesis

0.81	GO:0097493	structural molecule activity conferring elasticity
0.81	GO:0051371	muscle alpha-actinin binding
0.80	GO:0008307	structural constituent of muscle
0.70	GO:0051015	actin filament binding
0.44	GO:0032036	myosin heavy chain binding
0.40	GO:0042802	identical protein binding
0.37	GO:0001671	ATPase activator activity
0.36	GO:0070003	threonine-type peptidase activity
0.35	GO:0004175	endopeptidase activity

0.81	GO:0005859	muscle myosin complex
0.80	GO:0031672	A band
0.75	GO:0030018	Z disc
0.56	GO:0032982	myosin filament
0.44	GO:0097512	cardiac myofibril
0.42	GO:0036379	myofilament
0.38	GO:0005794	Golgi apparatus
0.37	GO:0019773	proteasome core complex, alpha-subunit complex
0.30	GO:0031224	intrinsic component of membrane

sp|O88600|HSP74_RAT
Heat shock 70 kDa protein 4
Search

HSPA4

0.94	Epididymis secretory sperm binding protein Li 5a

0.54	GO:0045040	protein import into mitochondrial outer membrane
0.53	GO:0051131	chaperone-mediated protein complex assembly
0.35	GO:0043392	negative regulation of DNA binding
0.35	GO:0032092	positive regulation of protein binding
0.35	GO:0045766	positive regulation of angiogenesis
0.35	GO:0001822	kidney development
0.35	GO:0006986	response to unfolded protein
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0009408	response to heat
0.34	GO:0001933	negative regulation of protein phosphorylation

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0046872	metal ion binding

0.53	GO:0070062	extracellular exosome
0.47	GO:0005829	cytosol
0.35	GO:0005811	lipid droplet
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|O88618|FTCD_RAT
Formimidoyltransferase-cyclodeaminase
Search

FTCD

0.80	Formimidoyltransferase-cyclodeaminase

0.39	GO:0019557	histidine catabolic process to glutamate and formate
0.39	GO:0043606	formamide metabolic process
0.39	GO:0035999	tetrahydrofolate interconversion
0.37	GO:0007010	cytoskeleton organization
0.33	GO:0006352	DNA-templated transcription, initiation
0.33	GO:0015074	DNA integration
0.33	GO:0006310	DNA recombination

0.84	GO:0005542	folic acid binding
0.51	GO:0016740	transferase activity
0.50	GO:0008017	microtubule binding
0.43	GO:0030412	formimidoyltetrahydrofolate cyclodeaminase activity
0.36	GO:0019215	intermediate filament binding
0.33	GO:0016866	intramolecular transferase activity
0.33	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity
0.32	GO:0003677	DNA binding

0.59	GO:0030868	smooth endoplasmic reticulum membrane
0.52	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.40	GO:0005814	centriole
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.51	EC:2	GO:0016740
0.43	KEGG:R02302	GO:0030412

sp|O88626|GALR3_RAT
Galanin receptor type 3
Search

GALR3

0.95	Galanin receptor type 3

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0007194	negative regulation of adenylate cyclase activity
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:1902606	regulation of large conductance calcium-activated potassium channel activity
0.50	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.49	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.49	GO:2001259	positive regulation of cation channel activity
0.46	GO:0031175	neuron projection development
0.37	GO:0019933	cAMP-mediated signaling
0.37	GO:0007631	feeding behavior

0.70	GO:0004930	G-protein coupled receptor activity
0.61	GO:0001653	peptide receptor activity
0.60	GO:0017046	peptide hormone binding
0.38	GO:0042923	neuropeptide binding
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0005515	protein binding

0.51	GO:0097730	non-motile cilium
0.44	GO:0005887	integral component of plasma membrane
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane

sp|O88628|O51E2_RAT
Olfactory receptor 51E2
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:1900135	positive regulation of renin secretion into blood stream
0.56	GO:0045777	positive regulation of blood pressure
0.55	GO:0071398	cellular response to fatty acid
0.52	GO:0043401	steroid hormone mediated signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.52	GO:0003707	steroid hormone receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O88637|PCY2_RAT
Ethanolamine-phosphate cytidylyltransferase
Search

PCYT2

0.83	Ethanolamine-phosphate cytidylyltransferase

0.49	GO:0009058	biosynthetic process
0.39	GO:0046337	phosphatidylethanolamine metabolic process

0.55	GO:0016779	nucleotidyltransferase activity
0.39	GO:0070403	NAD+ binding
0.34	GO:0003723	RNA binding

0.34

GO:0005789

endoplasmic reticulum membrane

0.55

GO:0016779

sp|O88644|GRIFN_RAT
Grifin
Search

GRIFIN

0.61

Galectin

0.36

GO:1902476

chloride transmembrane transport

0.70	GO:0030246	carbohydrate binding
0.36	GO:0005254	chloride channel activity
0.36	GO:0005515	protein binding
0.35	GO:0016936	galactoside binding

0.37	GO:0034707	chloride channel complex
0.34	GO:0005886	plasma membrane

sp|O88656|ARC1B_RAT
Actin-related protein 2/3 complex subunit 1B
Search

ARPC1B

0.75	Actin-related protein 2/3 complex subunit

0.80	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.40	GO:0032355	response to estradiol
0.40	GO:0043627	response to estrogen
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0048013	ephrin receptor signaling pathway

0.69	GO:0003779	actin binding
0.52	GO:0032403	protein complex binding
0.51	GO:0005200	structural constituent of cytoskeleton

0.79	GO:0005885	Arp2/3 protein complex
0.47	GO:0005737	cytoplasm
0.45	GO:0036195	muscle cell projection membrane
0.42	GO:0036284	tubulobulbar complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

sp|O88658|KIF1B_RAT
Kinesin-like protein KIF1B
Search

KIF1B

0.96	Kinesin family member 1Bbeta isoform III

0.74	GO:0007018	microtubule-based movement
0.64	GO:0007270	neuron-neuron synaptic transmission
0.63	GO:0051654	establishment of mitochondrion localization
0.63	GO:0007274	neuromuscular synaptic transmission
0.62	GO:0030705	cytoskeleton-dependent intracellular transport
0.56	GO:0048917	posterior lateral line ganglion development
0.55	GO:0048918	posterior lateral line nerve development
0.54	GO:1990535	neuron projection maintenance
0.53	GO:0030225	macrophage differentiation
0.52	GO:0048675	axon extension

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0016887	ATPase activity

0.62	GO:1904115	axon cytoplasm
0.58	GO:0005875	microtubule associated complex
0.57	GO:0030659	cytoplasmic vesicle membrane
0.48	GO:0005739	mitochondrion

0.49

GO:0016887

sp|O88664|TAOK1_RAT
Serine/threonine-protein kinase TAO1
Search

TAOK1

0.93	LOW QUALITY PROTEIN: serine/threonine-protein kinase TAO1

0.63	GO:0006468	protein phosphorylation
0.58	GO:0097194	execution phase of apoptosis
0.57	GO:0007095	mitotic G2 DNA damage checkpoint
0.56	GO:0046330	positive regulation of JNK cascade
0.48	GO:0000186	activation of MAPKK activity
0.48	GO:0031098	stress-activated protein kinase signaling cascade
0.46	GO:0007399	nervous system development
0.45	GO:0042981	regulation of apoptotic process
0.38	GO:0051493	regulation of cytoskeleton organization
0.38	GO:0060322	head development

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0043539	protein serine/threonine kinase activator activity
0.35	GO:0019901	protein kinase binding
0.35	GO:0031489	myosin V binding
0.35	GO:0038191	neuropilin binding
0.35	GO:0008022	protein C-terminus binding

0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0043235	receptor complex
0.33	GO:0005730	nucleolus
0.33	GO:0097708	intracellular vesicle

sp|O88671|DLL3_RAT
Delta-like protein 3
Search

DLL3

0.97	Delta like canonical Notch ligand 3

0.69	GO:0007386	compartment pattern specification
0.66	GO:0048339	paraxial mesoderm development
0.65	GO:0007219	Notch signaling pathway
0.65	GO:0001756	somitogenesis
0.63	GO:0050768	negative regulation of neurogenesis
0.61	GO:0001501	skeletal system development
0.49	GO:0045165	cell fate commitment
0.49	GO:0008593	regulation of Notch signaling pathway
0.47	GO:1903670	regulation of sprouting angiogenesis
0.47	GO:0021510	spinal cord development

0.70	GO:0005509	calcium ion binding
0.53	GO:0005112	Notch binding
0.41	GO:0030957	Tat protein binding
0.40	GO:0097110	scaffold protein binding
0.33	GO:0005201	extracellular matrix structural constituent
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0030165	PDZ domain binding
0.32	GO:0042802	identical protein binding

0.39	GO:0016324	apical plasma membrane
0.39	GO:0098857	membrane microdomain
0.39	GO:0005912	adherens junction
0.38	GO:0031410	cytoplasmic vesicle
0.33	GO:0005938	cell cortex
0.33	GO:0005578	proteinaceous extracellular matrix
0.32	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005887	integral component of plasma membrane
0.31	GO:0005634	nucleus

sp|O88677|BTG3_RAT
Protein BTG3
Search

BTG3

0.92	BTG anti-proliferation factor 3

0.67	GO:0008285	negative regulation of cell proliferation
0.65	GO:0045930	negative regulation of mitotic cell cycle
0.37	GO:0006979	response to oxidative stress
0.34	GO:0021542	dentate gyrus development
0.34	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.34	GO:0035914	skeletal muscle cell differentiation
0.34	GO:0008306	associative learning
0.34	GO:0021954	central nervous system neuron development
0.34	GO:2000177	regulation of neural precursor cell proliferation
0.34	GO:0009952	anterior/posterior pattern specification

0.38	GO:0005515	protein binding
0.35	GO:0016286	small conductance calcium-activated potassium channel activity

0.43	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O88751|CABP1_RAT
Calcium-binding protein 1
Search

CABP1

0.86	Calcium binding protein 1

0.70	GO:0005509	calcium ion binding
0.44	GO:0048306	calcium-dependent protein binding

0.44	GO:0005794	Golgi apparatus
0.44	GO:0014069	postsynaptic density
0.40	GO:0098588	bounding membrane of organelle
0.40	GO:0031984	organelle subcompartment
0.38	GO:0005886	plasma membrane

tr|O88752|O88752_RAT
Epsilon 1 globin
Search

0.78	hemoglobin subunit epsilon

0.79	GO:0015671	oxygen transport
0.40	GO:0051291	protein heterooligomerization
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0014070	response to organic cyclic compound
0.37	GO:0007596	blood coagulation
0.36	GO:0070293	renal absorption
0.36	GO:0042542	response to hydrogen peroxide
0.35	GO:0010942	positive regulation of cell death
0.35	GO:0042744	hydrogen peroxide catabolic process
0.34	GO:0098869	cellular oxidant detoxification

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.41	GO:0030492	hemoglobin binding
0.37	GO:0031720	haptoglobin binding
0.34	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.38	GO:0072562	blood microparticle
0.37	GO:0031838	haptoglobin-hemoglobin complex

0.34	EC:1.11.1.7	GO:0004601
0.34	KEGG:R03532	GO:0004601

tr|O88753|O88753_RAT
Epsilon 2 globin
Search

0.80	G-gamma globin Paulinia variant

0.79	GO:0015671	oxygen transport
0.42	GO:0051291	protein heterooligomerization
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0014070	response to organic cyclic compound
0.37	GO:0007596	blood coagulation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0031721	hemoglobin alpha binding

0.83	GO:0005833	hemoglobin complex
0.37	GO:0072562	blood microparticle

tr|O88754|O88754_RAT
Epsilon 3 globin
Search

0.82	Hemoglobin subunit epsilon

0.79	GO:0015671	oxygen transport
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0051291	protein heterooligomerization
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.41	GO:0031721	hemoglobin alpha binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity

0.83	GO:0005833	hemoglobin complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O88758|KCNS1_RAT
Potassium voltage-gated channel subfamily S member 1
Search

KCNS1

0.96	Potassium voltage-gated channel modifier subfamily S member 1

0.77	GO:0051260	protein homooligomerization
0.76	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.63	GO:0043266	regulation of potassium ion transport
0.62	GO:0022898	regulation of transmembrane transporter activity
0.44	GO:0050794	regulation of cellular process
0.37	GO:0052547	regulation of peptidase activity
0.37	GO:0051346	negative regulation of hydrolase activity
0.37	GO:0051248	negative regulation of protein metabolic process

0.78	GO:0005249	voltage-gated potassium channel activity
0.58	GO:0015459	potassium channel regulator activity
0.37	GO:0030414	peptidase inhibitor activity
0.34	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.60	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005576	extracellular region

sp|O88759|KCNS3_RAT
Potassium voltage-gated channel subfamily S member 3
Search

KCNS3

0.97	Potassium voltage-gated channel delayed rectifier subfamily S member 3

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.47	GO:0043266	regulation of potassium ion transport
0.46	GO:0022898	regulation of transmembrane transporter activity
0.37	GO:0050794	regulation of cellular process
0.34	GO:0002791	regulation of peptide secretion
0.34	GO:0051223	regulation of protein transport
0.34	GO:0010817	regulation of hormone levels
0.34	GO:0023051	regulation of signaling

0.78	GO:0005249	voltage-gated potassium channel activity
0.39	GO:0015459	potassium channel regulator activity
0.32	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.51	GO:0005794	Golgi apparatus
0.49	GO:0005829	cytosol
0.45	GO:0048471	perinuclear region of cytoplasm

sp|O88761|PSMD1_RAT
26S proteasome non-ATPase regulatory subunit 1
Search

PSMD1

0.91	26S proteasome non-ATPase regulatory subunit 1

0.74	GO:0042176	regulation of protein catabolic process
0.67	GO:0050790	regulation of catalytic activity
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.69	GO:0030234	enzyme regulator activity
0.41	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding

0.71	GO:1905369	endopeptidase complex
0.58	GO:0043234	protein complex
0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.34	GO:0012505	endomembrane system
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part
0.31	GO:0099023	tethering complex

sp|O88763|PK3C3_RAT
Phosphatidylinositol 3-kinase catalytic subunit type 3
Search

PIK3C3

0.92	Phosphatidylinositol 3-kinase catalytic subunit type 3

0.81	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.79	GO:0048015	phosphatidylinositol-mediated signaling
0.73	GO:0046854	phosphatidylinositol phosphorylation
0.56	GO:0045022	early endosome to late endosome transport
0.55	GO:0000045	autophagosome assembly
0.54	GO:0042149	cellular response to glucose starvation
0.52	GO:0032465	regulation of cytokinesis
0.51	GO:0006497	protein lipidation
0.48	GO:0030242	autophagy of peroxisome
0.46	GO:0034613	cellular protein localization

0.82	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.44	GO:0004672	protein kinase activity
0.35	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0044754	autolysosome
0.55	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.54	GO:0030496	midbody
0.53	GO:0045335	phagocytic vesicle
0.52	GO:0005770	late endosome
0.47	GO:0005829	cytosol
0.47	GO:0000407	phagophore assembly site
0.45	GO:0005777	peroxisome
0.37	GO:0005930	axoneme
0.35	GO:0030666	endocytic vesicle membrane

0.82	EC:2.7.1.137	GO:0016303
0.82	KEGG:R03362	GO:0016303

sp|O88764|DAPK3_RAT
Death-associated protein kinase 3
Search

DAPK3

0.96	Death-associated protein kinase 3

0.62	GO:0006468	protein phosphorylation
0.59	GO:0006915	apoptotic process
0.57	GO:0043519	regulation of myosin II filament organization
0.55	GO:0071346	cellular response to interferon-gamma
0.54	GO:2000249	regulation of actin cytoskeleton reorganization
0.54	GO:0090109	regulation of cell-substrate junction assembly
0.54	GO:1903391	regulation of adherens junction organization
0.53	GO:0001952	regulation of cell-matrix adhesion
0.53	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.53	GO:0030335	positive regulation of cell migration

0.66	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0043522	leucine zipper domain binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.50	GO:0017048	Rho GTPase binding
0.50	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.40	GO:0008022	protein C-terminus binding

0.54	GO:0016605	PML body
0.40	GO:0005884	actin filament
0.40	GO:0098857	membrane microdomain
0.38	GO:0005737	cytoplasm
0.37	GO:0000775	chromosome, centromeric region
0.35	GO:0012505	endomembrane system
0.35	GO:0005815	microtubule organizing center
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.66

GO:0004674

sp|O88766|MMP8_RAT
Neutrophil collagenase
Search

MMP8

0.56	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.55	GO:0035987	endodermal cell differentiation
0.49	GO:0032461	positive regulation of protein oligomerization
0.44	GO:0030574	collagen catabolic process
0.37	GO:0022617	extracellular matrix disassembly
0.36	GO:0002376	immune system process
0.36	GO:0001503	ossification
0.35	GO:0016477	cell migration
0.35	GO:0045055	regulated exocytosis
0.35	GO:0001775	cell activation

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.47	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005509	calcium ion binding

0.74	GO:0031012	extracellular matrix
0.49	GO:0005615	extracellular space
0.41	GO:0005581	collagen trimer
0.39	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|O88767|PARK7_RAT
Protein DJ-1
Search

PARK7

0.96	Parkinsonism associated deglycase

0.84	GO:0036530	protein deglycation, methylglyoxal removal
0.84	GO:0140041	cellular detoxification of methylglyoxal
0.84	GO:0106044	guanine deglycation
0.83	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity
0.82	GO:0033864	positive regulation of NAD(P)H oxidase activity
0.81	GO:1903189	glyoxal metabolic process
0.81	GO:0036471	cellular response to glyoxal
0.81	GO:0010273	detoxification of copper ion
0.81	GO:1903178	positive regulation of tyrosine 3-monooxygenase activity
0.81	GO:0036528	peptidyl-lysine deglycation

0.81	GO:0036470	tyrosine 3-monooxygenase activator activity
0.81	GO:0036478	L-dopa decarboxylase activator activity
0.78	GO:0044388	small protein activating enzyme binding
0.78	GO:1903135	cupric ion binding
0.77	GO:0016532	superoxide dismutase copper chaperone activity
0.77	GO:1903136	cuprous ion binding
0.76	GO:1990381	ubiquitin-specific protease binding
0.75	GO:0050681	androgen receptor binding
0.74	GO:0036524	protein deglycase activity
0.74	GO:0097110	scaffold protein binding

0.72	GO:0016605	PML body
0.71	GO:0005913	cell-cell adherens junction
0.70	GO:0005747	mitochondrial respiratory chain complex I
0.69	GO:0044297	cell body
0.68	GO:0048471	perinuclear region of cytoplasm
0.68	GO:0098793	presynapse
0.68	GO:0005758	mitochondrial intermembrane space
0.66	GO:0043005	neuron projection
0.64	GO:0005759	mitochondrial matrix
0.62	GO:0000785	chromatin

0.64

EC:1.11.1.15

GO:0051920

sp|O88775|EMB_RAT
Embigin
Search

EMB

0.96

Embigin

0.46	GO:0035879	plasma membrane lactate transport
0.37	GO:0007155	cell adhesion

0.36	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.35	GO:0005515	protein binding

0.41	GO:0045202	synapse
0.41	GO:0030054	cell junction
0.39	GO:0005887	integral component of plasma membrane

sp|O88777|PSN2_RAT
Presenilin-2
Search

PSEN2

0.80	Presenilin

0.81	GO:0007219	Notch signaling pathway
0.80	GO:0042987	amyloid precursor protein catabolic process
0.75	GO:0016485	protein processing
0.58	GO:0006509	membrane protein ectodomain proteolysis
0.56	GO:0035556	intracellular signal transduction
0.53	GO:0050435	amyloid-beta metabolic process
0.49	GO:0043085	positive regulation of catalytic activity
0.49	GO:0007220	Notch receptor processing
0.45	GO:0043066	negative regulation of apoptotic process
0.44	GO:0006816	calcium ion transport

0.76	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving
0.34	GO:0005515	protein binding
0.33	GO:0008324	cation transmembrane transporter activity

0.73	GO:0000139	Golgi membrane
0.71	GO:0005789	endoplasmic reticulum membrane
0.54	GO:0005637	nuclear inner membrane
0.52	GO:0000776	kinetochore
0.52	GO:0005813	centrosome
0.49	GO:0035253	ciliary rootlet
0.48	GO:0043198	dendritic shaft
0.48	GO:0005887	integral component of plasma membrane
0.48	GO:0031594	neuromuscular junction
0.48	GO:0030426	growth cone

0.76

GO:0042500

sp|O88778|BSN_RAT
Protein bassoon
Search

BSN

0.97	Bassoon presynaptic cytomatrix protein

0.85	GO:0007416	synapse assembly
0.71	GO:0099526	presynapse to nucleus signaling pathway
0.67	GO:0035418	protein localization to synapse
0.41	GO:0048790	maintenance of presynaptic active zone structure
0.41	GO:0008090	retrograde axonal transport
0.38	GO:0007268	chemical synaptic transmission
0.38	GO:0007010	cytoskeleton organization
0.36	GO:0006508	proteolysis
0.32	GO:0030073	insulin secretion
0.32	GO:0019933	cAMP-mediated signaling

0.52	GO:0046872	metal ion binding
0.42	GO:0098882	structural constituent of presynaptic active zone
0.41	GO:0001222	transcription corepressor binding
0.40	GO:0045503	dynein light chain binding
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.33	GO:0005522	profilin binding

0.83	GO:0048786	presynaptic active zone
0.64	GO:0044306	neuron projection terminus
0.64	GO:0014069	postsynaptic density
0.63	GO:0099738	cell cortex region
0.62	GO:0030425	dendrite
0.61	GO:0030424	axon
0.59	GO:0009986	cell surface
0.47	GO:0060076	excitatory synapse
0.45	GO:0099569	presynaptic cytoskeleton
0.43	GO:0030054	cell junction

sp|O88779|RHBL1_RAT
Rhomboid-related protein 1 (Fragment)
Search

0.41	Rhomboid-like protein (Fragment)

0.61	GO:0006508	proteolysis
0.43	GO:0051604	protein maturation
0.33	GO:0043547	positive regulation of GTPase activity
0.33	GO:0016567	protein ubiquitination

0.69	GO:0004252	serine-type endopeptidase activity
0.54	GO:0005509	calcium ion binding
0.33	GO:1902936	phosphatidylinositol bisphosphate binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.69	EC:3.4.21	GO:0004252
0.33	KEGG:R03876	GO:0004842

sp|O88780|KLK8_RAT
Kallikrein-8
Search

0.93	LOW QUALITY PROTEIN: kallikrein-8

0.61	GO:0006508	proteolysis
0.55	GO:0031642	negative regulation of myelination
0.54	GO:0043616	keratinocyte proliferation
0.53	GO:0048681	negative regulation of axon regeneration
0.52	GO:0007613	memory
0.51	GO:0050807	regulation of synapse organization
0.50	GO:0050808	synapse organization
0.50	GO:0009611	response to wounding
0.50	GO:0008219	cell death
0.49	GO:0048812	neuron projection morphogenesis

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.34	GO:0005515	protein binding

0.55	GO:0097180	serine protease inhibitor complex
0.49	GO:0005615	extracellular space
0.38	GO:0005737	cytoplasm
0.37	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0012505	endomembrane system
0.34	GO:0043229	intracellular organelle
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|O88788|AG10B_RAT
Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
Search

0.89	Asparagine-linked glycosylation 10

0.83	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.54	GO:0060117	auditory receptor cell development
0.51	GO:0007605	sensory perception of sound
0.39	GO:1901980	positive regulation of inward rectifier potassium channel activity
0.38	GO:0060050	positive regulation of protein glycosylation
0.37	GO:0006486	protein glycosylation
0.33	GO:0048366	leaf development
0.33	GO:0009651	response to salt stress
0.32	GO:0006468	protein phosphorylation

0.85	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
0.43	GO:0106073	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity
0.38	GO:0015459	potassium channel regulator activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.1

GO:0004583

tr|O88791|O88791_RAT
High mobility group AT-hook 2
Search

HMGA2

0.95	High mobility group protein HMGI-C

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0090402	oncogene-induced cell senescence
0.54	GO:0035986	senescence-associated heterochromatin focus assembly
0.53	GO:2000774	positive regulation of cellular senescence
0.49	GO:0031052	chromosome breakage
0.49	GO:0035978	histone H2A-S139 phosphorylation
0.49	GO:0003131	mesodermal-endodermal cell signaling
0.48	GO:2000685	positive regulation of cellular response to X-ray

0.55	GO:0003677	DNA binding
0.49	GO:0035501	MH1 domain binding
0.48	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.48	GO:0035500	MH2 domain binding
0.47	GO:0070742	C2H2 zinc finger domain binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.46	GO:0004677	DNA-dependent protein kinase activity
0.46	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0042975	peroxisome proliferator activated receptor binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.47	GO:0071141	SMAD protein complex
0.42	GO:0032993	protein-DNA complex
0.41	GO:0070013	intracellular organelle lumen
0.36	GO:0005667	transcription factor complex
0.35	GO:0005925	focal adhesion
0.33	GO:0005829	cytosol

0.47

EC:4.2.99.18

GO:0003906

sp|O88794|PNPO_RAT
Pyridoxine-5'-phosphate oxidase
Search

PNPO

0.47	Pyridoxamine 5'-phosphate oxidase

0.77	GO:0008615	pyridoxine biosynthetic process
0.76	GO:0042823	pyridoxal phosphate biosynthetic process
0.52	GO:0055114	oxidation-reduction process

0.81	GO:0004733	pyridoxamine-phosphate oxidase activity
0.70	GO:0010181	FMN binding
0.38	GO:0042803	protein homodimerization activity
0.36	GO:0030170	pyridoxal phosphate binding
0.33	GO:0052856	NADHX epimerase activity
0.32	GO:0046872	metal ion binding

0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome

0.81

EC:1.4.3.5

GO:0004733

sp|O88797|DAB2_RAT
Disabled homolog 2
Search

DAB2

0.97	Differentially-expressed protein 2

0.87	GO:0035026	leading edge cell differentiation
0.86	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.86	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway
0.86	GO:2000643	positive regulation of early endosome to late endosome transport
0.86	GO:0060766	negative regulation of androgen receptor signaling pathway
0.86	GO:0060391	positive regulation of SMAD protein import into nucleus
0.85	GO:1903077	negative regulation of protein localization to plasma membrane
0.85	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.85	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.85	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation

0.84	GO:0035615	clathrin adaptor activity
0.83	GO:0046332	SMAD binding
0.81	GO:0008022	protein C-terminus binding
0.79	GO:0038024	cargo receptor activity
0.47	GO:0035612	AP-2 adaptor complex binding
0.45	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.45	GO:0005178	integrin binding

0.87	GO:0070022	transforming growth factor beta receptor complex
0.81	GO:0001650	fibrillar center
0.79	GO:0005905	clathrin-coated pit
0.78	GO:0030136	clathrin-coated vesicle
0.45	GO:0030662	coated vesicle membrane
0.44	GO:0016324	apical plasma membrane
0.44	GO:0005925	focal adhesion
0.44	GO:0070062	extracellular exosome
0.43	GO:0030118	clathrin coat
0.40	GO:0098797	plasma membrane protein complex

sp|O88801|HOME2_RAT
Homer protein homolog 2
Search

HOMER2

0.88	Homer protein like protein 2

0.70	GO:0048875	chemical homeostasis within a tissue
0.69	GO:0048148	behavioral response to cocaine
0.68	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.65	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.64	GO:0007605	sensory perception of sound
0.55	GO:0006468	protein phosphorylation
0.41	GO:0007216	G-protein coupled glutamate receptor signaling pathway
0.37	GO:0021628	olfactory nerve formation
0.37	GO:0071699	olfactory placode morphogenesis

0.72	GO:0030160	GKAP/Homer scaffold activity
0.61	GO:0035256	G-protein coupled glutamate receptor binding
0.60	GO:0004674	protein serine/threonine kinase activity
0.58	GO:0003779	actin binding
0.49	GO:0032559	adenyl ribonucleotide binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0019904	protein domain specific binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity

0.69	GO:0032426	stereocilium tip
0.63	GO:0045177	apical part of cell
0.42	GO:0005737	cytoplasm
0.42	GO:0014069	postsynaptic density
0.42	GO:0043025	neuronal cell body
0.42	GO:0030425	dendrite
0.41	GO:0045211	postsynaptic membrane
0.40	GO:0030054	cell junction

0.60

GO:0004674

sp|O88806|PADI1_RAT
Protein-arginine deiminase type-1
Search

0.92	Peptidylarginine deiminase type III

0.81	GO:0018101	protein citrullination
0.54	GO:0016570	histone modification
0.52	GO:0019546	arginine deiminase pathway
0.49	GO:0019827	stem cell population maintenance
0.48	GO:0006338	chromatin remodeling
0.47	GO:0006334	nucleosome assembly
0.40	GO:0010848	regulation of chromatin disassembly
0.39	GO:1901624	negative regulation of lymphocyte chemotaxis
0.39	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.39	GO:0030520	intracellular estrogen receptor signaling pathway

0.80	GO:0004668	protein-arginine deiminase activity
0.69	GO:0005509	calcium ion binding
0.51	GO:0042802	identical protein binding
0.48	GO:0016990	arginine deiminase activity
0.48	GO:0034618	arginine binding
0.43	GO:0046983	protein dimerization activity
0.39	GO:0030331	estrogen receptor binding

0.49	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.40	GO:0043234	protein complex
0.37	GO:0070062	extracellular exosome
0.36	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.5.3.15

GO:0004668

sp|O88807|PADI4_RAT
Protein-arginine deiminase type-4
Search

0.91	Peptidylarginine deiminase type III

0.81	GO:0018101	protein citrullination
0.57	GO:0019546	arginine deiminase pathway
0.55	GO:0016570	histone modification
0.53	GO:0019827	stem cell population maintenance
0.51	GO:0006338	chromatin remodeling
0.51	GO:0006334	nucleosome assembly
0.39	GO:0045087	innate immune response
0.37	GO:0010848	regulation of chromatin disassembly
0.37	GO:1901624	negative regulation of lymphocyte chemotaxis
0.37	GO:0070100	negative regulation of chemokine-mediated signaling pathway

0.79	GO:0004668	protein-arginine deiminase activity
0.69	GO:0005509	calcium ion binding
0.54	GO:0042802	identical protein binding
0.52	GO:0016990	arginine deiminase activity
0.52	GO:0034618	arginine binding
0.46	GO:0046983	protein dimerization activity
0.36	GO:0030331	estrogen receptor binding

0.49	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.43	GO:0043233	organelle lumen
0.43	GO:0043234	protein complex
0.40	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.34	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.79

EC:3.5.3.15

GO:0004668

sp|O88808|TUB_RAT
Tubby protein homolog
Search

TUB

0.89	Tubby bipartite transcription factor

0.87	GO:0097500	receptor localization to non-motile cilium
0.87	GO:1903546	protein localization to photoreceptor outer segment
0.85	GO:0050766	positive regulation of phagocytosis
0.84	GO:0006910	phagocytosis, recognition
0.84	GO:0045494	photoreceptor cell maintenance
0.81	GO:0060041	retina development in camera-type eye
0.79	GO:0007605	sensory perception of sound
0.59	GO:0009725	response to hormone

0.75	GO:0032403	protein complex binding
0.68	GO:0035091	phosphatidylinositol binding

0.68	GO:0005929	cilium
0.66	GO:0005829	cytosol
0.64	GO:0005576	extracellular region
0.50	GO:0005634	nucleus
0.47	GO:0005886	plasma membrane

sp|O88813|ACSL5_RAT
Long-chain-fatty-acid--CoA ligase 5
Search

ACSL5

0.78	LOW QUALITY PROTEIN: long-chain-fatty-acid--CoA ligase 5

0.42	GO:0001676	long-chain fatty acid metabolic process
0.42	GO:0044539	long-chain fatty acid import
0.41	GO:0033211	adiponectin-activated signaling pathway
0.39	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.38	GO:2001236	regulation of extrinsic apoptotic signaling pathway
0.38	GO:0008610	lipid biosynthetic process
0.37	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport
0.36	GO:0032000	positive regulation of fatty acid beta-oxidation
0.36	GO:0010867	positive regulation of triglyceride biosynthetic process
0.36	GO:0070723	response to cholesterol

0.52	GO:0016874	ligase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.32	GO:0005509	calcium ion binding

0.49	GO:0005730	nucleolus
0.45	GO:0005739	mitochondrion
0.45	GO:0019866	organelle inner membrane
0.37	GO:0031968	organelle outer membrane
0.36	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.52

EC:6

GO:0016874

sp|O88823|JTB_RAT
Protein JTB
Search

JTB

0.97	Jumping translocation breakpoint

0.72	GO:0008637	apoptotic mitochondrial changes
0.68	GO:0000281	mitotic cytokinesis
0.66	GO:0045860	positive regulation of protein kinase activity
0.64	GO:0042127	regulation of cell proliferation

0.66

GO:0019901

protein kinase binding

0.70	GO:0030496	midbody
0.66	GO:0005813	centrosome
0.65	GO:0005819	spindle
0.53	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|O88828|RPAB2_RAT
DNA-directed RNA polymerases I, II, and III subunit RPABC2
Search

POLR2F

0.93	RNA polymerase II subunit F

0.58	GO:0006351	transcription, DNA-templated
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0032481	positive regulation of type I interferon production
0.35	GO:0060964	regulation of gene silencing by miRNA
0.35	GO:0045815	positive regulation of gene expression, epigenetic
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.33	GO:0004427	inorganic diphosphatase activity
0.33	GO:0000287	magnesium ion binding

0.79	GO:0005665	DNA-directed RNA polymerase II, core complex
0.47	GO:0005736	DNA-directed RNA polymerase I complex
0.47	GO:0005666	DNA-directed RNA polymerase III complex
0.37	GO:0001650	fibrillar center
0.33	GO:0005829	cytosol

0.70	EC:2.7.7.6	GO:0003899
0.33	KEGG:R00004	GO:0004427

sp|O88831|KKCC2_RAT
Calcium/calmodulin-dependent protein kinase kinase 2
Search

CAMKK2

0.95	Calcium/calmodulin-dependent protein kinase kinase 2 beta

0.63	GO:0006468	protein phosphorylation
0.61	GO:0061762	CAMKK-AMPK signaling cascade
0.54	GO:0001934	positive regulation of protein phosphorylation
0.47	GO:0018210	peptidyl-threonine modification
0.46	GO:0018209	peptidyl-serine modification
0.45	GO:0033674	positive regulation of kinase activity
0.45	GO:0045859	regulation of protein kinase activity
0.36	GO:1903599	positive regulation of autophagy of mitochondrion
0.35	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0034614	cellular response to reactive oxygen species

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005509	calcium ion binding
0.46	GO:0005516	calmodulin binding
0.35	GO:0030295	protein kinase activator activity

0.49	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.36	GO:0042995	cell projection

sp|O88846|RNF4_RAT
E3 ubiquitin-protein ligase RNF4
Search

RNF4

0.90	Ring finger protein 4

0.85	GO:0090234	regulation of kinetochore assembly
0.81	GO:0090169	regulation of spindle assembly
0.77	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.76	GO:0046685	response to arsenic-containing substance
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0016567	protein ubiquitination

0.69	GO:0042802	identical protein binding
0.67	GO:0008134	transcription factor binding
0.58	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0046872	metal ion binding

0.84	GO:0016605	PML body
0.47	GO:0005737	cytoplasm

sp|O88850|HIPK3_RAT
Homeodomain-interacting protein kinase 3
Search

HIPK3

0.97	Homeodomain interacting protein kinase 3

0.68	GO:0043508	negative regulation of JUN kinase activity
0.67	GO:0009299	mRNA transcription
0.64	GO:0018107	peptidyl-threonine phosphorylation
0.62	GO:0018105	peptidyl-serine phosphorylation
0.61	GO:0043066	negative regulation of apoptotic process
0.35	GO:0071466	cellular response to xenobiotic stimulus

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003677	DNA binding

0.65	GO:0016605	PML body
0.55	GO:0005829	cytosol

sp|O88867|KMO_RAT
Kynurenine 3-monooxygenase
Search

KMO

0.73	Kynurenine 3-monooxygenase

0.74	GO:0019805	quinolinate biosynthetic process
0.73	GO:0006569	tryptophan catabolic process
0.72	GO:0043420	anthranilate metabolic process
0.72	GO:0034354	'de novo' NAD biosynthetic process from tryptophan
0.54	GO:0070189	kynurenine metabolic process
0.54	GO:0009651	response to salt stress
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0044550	secondary metabolite biosynthetic process
0.35	GO:0001878	response to yeast
0.35	GO:0072015	glomerular visceral epithelial cell development

0.81	GO:0004502	kynurenine 3-monooxygenase activity
0.72	GO:0071949	FAD binding
0.59	GO:0016174	NAD(P)H oxidase activity

0.67	GO:0005741	mitochondrial outer membrane
0.43	GO:0019866	organelle inner membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.81	EC:1.14.13.9	GO:0004502
0.81	KEGG:R01960	GO:0004502

sp|O88869|RASF9_RAT
Ras association domain-containing protein 9
Search

RASSF9

0.97	Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor

0.75	GO:0016197	endosomal transport
0.60	GO:0007165	signal transduction
0.36	GO:0006605	protein targeting
0.34	GO:0055114	oxidation-reduction process

0.37	GO:0004497	monooxygenase activity
0.36	GO:0005515	protein binding
0.34	GO:0005215	transporter activity

0.57	GO:0012510	trans-Golgi network transport vesicle membrane
0.53	GO:0005768	endosome
0.50	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.33	GO:0000922	spindle pole
0.33	GO:0005815	microtubule organizing center

sp|O88871|GABR2_RAT
Gamma-aminobutyric acid type B receptor subunit 2
Search

GABBR2

0.92	LOW QUALITY PROTEIN: gamma-aminobutyric acid type B receptor subunit 2

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0007194	negative regulation of adenylate cyclase activity
0.35	GO:0007268	chemical synaptic transmission

0.84	GO:0004965	G-protein coupled GABA receptor activity
0.52	GO:0046982	protein heterodimerization activity

0.62	GO:0038039	G-protein coupled receptor heterodimeric complex
0.60	GO:1902710	GABA receptor complex
0.53	GO:0043005	neuron projection
0.39	GO:0045211	postsynaptic membrane
0.39	GO:0005737	cytoplasm
0.38	GO:0030054	cell junction
0.36	GO:0043204	perikaryon
0.35	GO:0120038	plasma membrane bounded cell projection part

sp|O88873|GMEB2_RAT
Glucocorticoid modulatory element-binding protein 2
Search

GMEB2

0.97	Glucocorticoid modulatory element-binding protein 2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.37	GO:0006366	transcription by RNA polymerase II
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.32	GO:0018108	peptidyl-tyrosine phosphorylation

0.79	GO:0003713	transcription coactivator activity
0.55	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.32	GO:0003723	RNA binding
0.31	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.50	GO:0043233	organelle lumen
0.45	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:2.7.10.2

GO:0004715

sp|O88881|BEGIN_RAT
Brain-enriched guanylate kinase-associated protein
Search

BEGAIN

0.97	Brain enriched guanylate kinase associated

0.56

GO:0016310

phosphorylation

0.58	GO:0016301	kinase activity
0.38	GO:0005515	protein binding

0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|O88884|AKAP1_RAT
A-kinase anchor protein 1, mitochondrial
Search

AKAP1

0.88	A-kinase anchoring protein 1

0.85

GO:0010738

regulation of protein kinase A signaling

0.85	GO:0034237	protein kinase A regulatory subunit binding
0.59	GO:0003723	RNA binding

0.61	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|O88900|GRB14_RAT
Growth factor receptor-bound protein 14
Search

GRB14

0.94	Growth factor receptor-bound protein 14

0.74	GO:0009967	positive regulation of signal transduction
0.70	GO:0046627	negative regulation of insulin receptor signaling pathway
0.60	GO:0007165	signal transduction
0.42	GO:0046325	negative regulation of glucose import
0.41	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.40	GO:0030178	negative regulation of Wnt signaling pathway
0.39	GO:0042326	negative regulation of phosphorylation
0.37	GO:1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation
0.36	GO:0032869	cellular response to insulin stimulus
0.35	GO:0050900	leukocyte migration

0.84	GO:0005070	SH3/SH2 adaptor activity
0.59	GO:0005102	receptor binding
0.56	GO:1990782	protein tyrosine kinase binding
0.53	GO:0032403	protein complex binding
0.52	GO:0042803	protein homodimerization activity
0.36	GO:0051219	phosphoprotein binding

0.43	GO:0043227	membrane-bounded organelle
0.42	GO:0005886	plasma membrane
0.41	GO:0043229	intracellular organelle
0.39	GO:0005737	cytoplasm
0.38	GO:0098805	whole membrane
0.37	GO:0012505	endomembrane system
0.36	GO:0043234	protein complex
0.35	GO:0044422	organelle part

sp|O88902|PTN23_RAT
Tyrosine-protein phosphatase non-receptor type 23 (Fragment)
Search

PTPN23

0.75	Tyrosine-protein phosphatase non-receptor type 23

0.84	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.79	GO:0060271	cilium assembly
0.78	GO:0030334	regulation of cell migration
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.59	GO:1903387	positive regulation of homophilic cell adhesion
0.57	GO:0061357	positive regulation of Wnt protein secretion
0.57	GO:2000643	positive regulation of early endosome to late endosome transport
0.56	GO:1903393	positive regulation of adherens junction organization
0.56	GO:0045022	early endosome to late endosome transport
0.54	GO:0032456	endocytic recycling

0.75	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0019901	protein kinase binding

0.53	GO:0036064	ciliary basal body
0.52	GO:0005769	early endosome
0.49	GO:0016604	nuclear body
0.47	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome

0.75

GO:0004725

sp|O88917|AGRL1_RAT
Adhesion G protein-coupled receptor L1
Search

0.74	Adhesion G protein-coupled receptor L1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0007166	cell surface receptor signaling pathway
0.53	GO:0051965	positive regulation of synapse assembly
0.40	GO:0090129	positive regulation of synapse maturation
0.40	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.39	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0016079	synaptic vesicle exocytosis
0.38	GO:0007420	brain development

0.72	GO:0004930	G-protein coupled receptor activity
0.68	GO:0030246	carbohydrate binding
0.41	GO:0016524	latrotoxin receptor activity
0.39	GO:0015643	toxic substance binding
0.38	GO:0050839	cell adhesion molecule binding

0.39	GO:0042734	presynaptic membrane
0.39	GO:0030426	growth cone
0.39	GO:0014069	postsynaptic density
0.38	GO:0030424	axon
0.37	GO:0030054	cell junction
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|O88923|AGRL2_RAT
Adhesion G protein-coupled receptor L2
Search

ADGRL2

0.89	Adhesion G protein-coupled receptor L2

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0051965	positive regulation of synapse assembly
0.35	GO:0048513	animal organ development
0.35	GO:0060322	head development
0.35	GO:0007417	central nervous system development
0.33	GO:0072359	circulatory system development
0.33	GO:0009888	tissue development
0.33	GO:0030154	cell differentiation
0.33	GO:0009653	anatomical structure morphogenesis

0.72	GO:0004930	G-protein coupled receptor activity
0.69	GO:0030246	carbohydrate binding
0.36	GO:0030165	PDZ domain binding
0.36	GO:0016524	latrotoxin receptor activity

0.35	GO:0043005	neuron projection
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|O88941|MOGS_RAT
Mannosyl-oligosaccharide glucosidase
Search

MOGS

0.83	Mannosyl-oligosaccharide glucosidase

0.72	GO:0009311	oligosaccharide metabolic process
0.35	GO:0043413	macromolecule glycosylation
0.35	GO:0009101	glycoprotein biosynthetic process
0.34	GO:0006457	protein folding
0.34	GO:0006464	cellular protein modification process

0.83	GO:0004573	mannosyl-oligosaccharide glucosidase activity
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.50	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0070062	extracellular exosome
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:3.2.1.106

GO:0004573

sp|O88943|KCNQ2_RAT
Potassium voltage-gated channel subfamily KQT member 2
Search

KCNQ2

0.95	Potassium voltage-gated channel subfamily KQT member 2

0.73	GO:0071805	potassium ion transmembrane transport
0.37	GO:0019226	transmission of nerve impulse
0.37	GO:0034765	regulation of ion transmembrane transport
0.34	GO:0007268	chemical synaptic transmission
0.33	GO:0007399	nervous system development
0.33	GO:0006414	translational elongation

0.77	GO:0005249	voltage-gated potassium channel activity
0.53	GO:0030506	ankyrin binding
0.49	GO:0005516	calmodulin binding
0.36	GO:0047485	protein N-terminus binding
0.33	GO:0003746	translation elongation factor activity
0.33	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding

0.77	GO:0008076	voltage-gated potassium channel complex
0.39	GO:0043194	axon initial segment
0.39	GO:0033268	node of Ranvier
0.36	GO:0009986	cell surface
0.33	GO:0043234	protein complex
0.31	GO:0005737	cytoplasm

sp|O88944|KCNQ3_RAT
Potassium voltage-gated channel subfamily KQT member 3
Search

KCNQ3

0.58	Voltage-gated potassium channel

0.73	GO:0071805	potassium ion transmembrane transport
0.60	GO:0060081	membrane hyperpolarization
0.40	GO:0034765	regulation of ion transmembrane transport
0.36	GO:0007268	chemical synaptic transmission
0.36	GO:0061548	ganglion development
0.36	GO:0014003	oligodendrocyte development
0.36	GO:0071242	cellular response to ammonium ion
0.33	GO:0042472	inner ear morphogenesis
0.33	GO:0007605	sensory perception of sound

0.77	GO:0005249	voltage-gated potassium channel activity
0.54	GO:0005516	calmodulin binding
0.36	GO:0044325	ion channel binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0019901	protein kinase binding

0.77	GO:0008076	voltage-gated potassium channel complex
0.60	GO:0043194	axon initial segment
0.60	GO:0033268	node of Ranvier
0.53	GO:0009986	cell surface
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.36	GO:0045121	membrane raft

sp|O88954|MPP3_RAT
MAGUK p55 subfamily member 3
Search

MPP3

0.97	Membrane palmitoylated protein 3

0.53	GO:0035335	peptidyl-tyrosine dephosphorylation
0.49	GO:0046710	GDP metabolic process
0.48	GO:0046037	GMP metabolic process
0.42	GO:0007165	signal transduction
0.41	GO:0016310	phosphorylation

0.68	GO:0030165	PDZ domain binding
0.55	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.53	GO:0004725	protein tyrosine phosphatase activity
0.49	GO:0004385	guanylate kinase activity

0.44

GO:0005887

integral component of plasma membrane

0.55

GO:0008138

sp|O88959|INHBE_RAT
Inhibin beta E chain
Search

INHBE

0.96	Inhibin beta E subunit

0.75	GO:0010469	regulation of receptor activity
0.57	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.57	GO:0060395	SMAD protein signal transduction
0.53	GO:0043408	regulation of MAPK cascade
0.51	GO:0048468	cell development
0.51	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.76	GO:0005179	hormone activity
0.57	GO:0005160	transforming growth factor beta receptor binding
0.54	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

sp|O88969|CST8_RAT
Cystatin-8
Search

CST8

0.69

Cystatin

0.76	GO:0010951	negative regulation of endopeptidase activity
0.57	GO:2000116	regulation of cysteine-type endopeptidase activity

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.59	GO:0002020	protease binding

0.64	GO:0009986	cell surface
0.58	GO:0005576	extracellular region
0.44	GO:0005737	cytoplasm

sp|O88984|NXF1_RAT
Nuclear RNA export factor 1
Search

NXF1

0.87	Nuclear RNA export factor 1

0.79	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0051028	mRNA transport
0.74	GO:0006405	RNA export from nucleus
0.53	GO:0010467	gene expression
0.33	GO:0016032	viral process
0.33	GO:0007275	multicellular organism development

0.58	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.56	GO:0016234	inclusion body
0.48	GO:0005737	cytoplasm
0.48	GO:0031974	membrane-enclosed lumen
0.48	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.44	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|O88989|MDHC_RAT
Malate dehydrogenase, cytoplasmic
Search

MDH1

0.46	Malate dehydrogenase

0.78	GO:0006108	malate metabolic process
0.69	GO:0006099	tricarboxylic acid cycle
0.60	GO:0005975	carbohydrate metabolic process
0.48	GO:0006734	NADH metabolic process
0.46	GO:0006107	oxaloacetate metabolic process
0.33	GO:0044283	small molecule biosynthetic process
0.32	GO:1901576	organic substance biosynthetic process

0.78	GO:0030060	L-malate dehydrogenase activity
0.36	GO:0051287	NAD binding
0.36	GO:0047860	diiodophenylpyruvate reductase activity
0.34	GO:0004470	malic enzyme activity
0.33	GO:0005515	protein binding

0.50	GO:0043209	myelin sheath
0.43	GO:0005739	mitochondrion
0.42	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.78	EC:1.1.1.37	GO:0030060
0.36	KEGG:R03431	GO:0047860

sp|O88994|MARC2_RAT
Mitochondrial amidoxime reducing component 2
Search

MARC2

0.90	MOCO sulfurase C-terminal domain containing 2

0.54	GO:0042126	nitrate metabolic process
0.43	GO:0055114	oxidation-reduction process
0.36	GO:0051410	detoxification of nitrogen compound
0.36	GO:0006805	xenobiotic metabolic process
0.32	GO:0006091	generation of precursor metabolites and energy

0.76	GO:0030151	molybdenum ion binding
0.67	GO:0030170	pyridoxal phosphate binding
0.56	GO:0008940	nitrate reductase activity
0.54	GO:0043546	molybdopterin cofactor binding
0.32	GO:0051537	2 iron, 2 sulfur cluster binding
0.32	GO:0009055	electron transfer activity

0.48	GO:0031966	mitochondrial membrane
0.47	GO:0019866	organelle inner membrane
0.42	GO:0031968	organelle outer membrane
0.40	GO:0005777	peroxisome
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.56

EC:1.7.99.4

GO:0008940

tr|O88996|O88996_RAT
BCL-W
Search

BCL2L2

0.96

BCL-WEL

0.76	GO:0006915	apoptotic process
0.74	GO:0042981	regulation of apoptotic process
0.64	GO:0038034	signal transduction in absence of ligand
0.63	GO:0060011	Sertoli cell proliferation
0.60	GO:0043069	negative regulation of programmed cell death
0.54	GO:0007166	cell surface receptor signaling pathway
0.51	GO:1902532	negative regulation of intracellular signal transduction
0.50	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
0.45	GO:0006974	cellular response to DNA damage stimulus
0.44	GO:0035556	intracellular signal transduction

0.63	GO:0097718	disordered domain specific binding
0.57	GO:0046982	protein heterodimerization activity
0.57	GO:0042802	identical protein binding
0.46	GO:0051400	BH domain binding
0.42	GO:0003723	RNA binding

0.65	GO:0097136	Bcl-2 family protein complex
0.50	GO:0005741	mitochondrial outer membrane
0.50	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.36	GO:0016607	nuclear speck
0.30	GO:0016021	integral component of membrane

sp|O89000|DPYD_RAT
Dihydropyrimidine dehydrogenase [NADP(+)]
Search

DPYD

0.89	Dihydropyrimidine dehydrogenase [NADP(+)]

0.85	GO:0019483	beta-alanine biosynthetic process
0.61	GO:0006214	thymidine catabolic process
0.58	GO:0006210	thymine catabolic process
0.55	GO:0006212	uracil catabolic process
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0006145	purine nucleobase catabolic process
0.49	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.35	GO:0051384	response to glucocorticoid
0.35	GO:0007584	response to nutrient
0.35	GO:0007623	circadian rhythm

0.85	GO:0017113	dihydropyrimidine dehydrogenase (NADP+) activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.51	GO:0004152	dihydroorotate dehydrogenase activity
0.51	GO:0042803	protein homodimerization activity
0.37	GO:0050661	NADP binding
0.36	GO:0002058	uracil binding
0.35	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0046872	metal ion binding
0.35	GO:0004159	dihydrouracil dehydrogenase (NAD+) activity
0.34	GO:0010181	FMN binding

0.48	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85	EC:1.3.1.2	GO:0017113
0.51	KEGG:R01868	GO:0004152

tr|O89035|O89035_RAT
Mitochondrial dicarboxylate carrier
Search

SLC25A10

0.89	Mitochondrial dicarboxylate carrier

0.64	GO:0006839	mitochondrial transport
0.49	GO:1902356	oxaloacetate(2-) transmembrane transport
0.49	GO:0071422	succinate transmembrane transport
0.48	GO:0071423	malate transmembrane transport
0.46	GO:0015709	thiosulfate transport
0.44	GO:0035435	phosphate ion transmembrane transport
0.44	GO:1902358	sulfate transmembrane transport
0.38	GO:0043043	peptide biosynthetic process
0.37	GO:0044267	cellular protein metabolic process
0.36	GO:0010467	gene expression

0.49	GO:0015131	oxaloacetate transmembrane transporter activity
0.49	GO:0015141	succinate transmembrane transporter activity
0.48	GO:0015140	malate transmembrane transporter activity
0.46	GO:0015117	thiosulfate transmembrane transporter activity
0.45	GO:0015291	secondary active transmembrane transporter activity
0.44	GO:0015116	sulfate transmembrane transporter activity
0.39	GO:0003735	structural constituent of ribosome
0.36	GO:0004967	glucagon receptor activity
0.36	GO:0015114	phosphate ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.53	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.39	GO:0005654	nucleoplasm
0.38	GO:0005840	ribosome
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O89038|MEF2D_RAT
Myocyte-specific enhancer factor 2D
Search

MEF2D

0.94	Myocyte-specific enhancer factor 2D

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0007512	adult heart development
0.56	GO:0001958	endochondral ossification
0.56	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.55	GO:0035914	skeletal muscle cell differentiation
0.55	GO:0002062	chondrocyte differentiation
0.54	GO:0001649	osteoblast differentiation
0.42	GO:0030241	skeletal muscle myosin thick filament assembly
0.41	GO:0060914	heart formation

0.76	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.67	GO:0046983	protein dimerization activity
0.54	GO:0033613	activating transcription factor binding
0.54	GO:0042826	histone deacetylase binding
0.53	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000987	proximal promoter sequence-specific DNA binding
0.49	GO:0042802	identical protein binding

0.60	GO:0005634	nucleus
0.46	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm

sp|O89039|ACKR3_RAT
Atypical chemokine receptor 3
Search

ACKR3

0.97	C-X-C chemokine receptor type 7

0.85	GO:0001570	vasculogenesis
0.81	GO:0001525	angiogenesis
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.71	GO:0006935	chemotaxis
0.61	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.60	GO:0031623	receptor internalization
0.59	GO:0070098	chemokine-mediated signaling pathway
0.59	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.46	GO:0048920	posterior lateral line neuromast primordium migration
0.42	GO:1905322	positive regulation of mesenchymal stem cell migration

0.85	GO:0019956	chemokine binding
0.85	GO:0015026	coreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.58	GO:0004896	cytokine receptor activity
0.57	GO:0005044	scavenger receptor activity
0.56	GO:0001653	peptide receptor activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0042923	neuropeptide binding
0.33	GO:0016500	protein-hormone receptor activity
0.32	GO:0030594	neurotransmitter receptor activity

0.57	GO:0005905	clathrin-coated pit
0.54	GO:0009986	cell surface
0.54	GO:0005768	endosome
0.44	GO:0005886	plasma membrane
0.44	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0061827	sperm head
0.33	GO:0097225	sperm midpiece
0.32	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

sp|O89040|PLCB2_RAT
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
Search

PLCB2

0.53	Phosphoinositide phospholipase C

0.72	GO:0016042	lipid catabolic process
0.62	GO:0035556	intracellular signal transduction
0.55	GO:0050913	sensory perception of bitter taste
0.50	GO:0007420	brain development
0.47	GO:0051726	regulation of cell cycle
0.41	GO:2000560	positive regulation of CD24 biosynthetic process
0.41	GO:2000438	negative regulation of monocyte extravasation
0.40	GO:0035723	interleukin-15-mediated signaling pathway
0.40	GO:0035722	interleukin-12-mediated signaling pathway
0.40	GO:2000344	positive regulation of acrosome reaction

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.65	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.40	GO:0005521	lamin binding
0.39	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.38	GO:0005516	calmodulin binding
0.38	GO:0005096	GTPase activator activity
0.37	GO:0019899	enzyme binding

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043209	myelin sheath
0.36	GO:0043233	organelle lumen
0.35	GO:0043228	non-membrane-bounded organelle

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

sp|O89042|DPOLA_RAT
DNA polymerase alpha catalytic subunit (Fragment)
Search

POLA1

0.48	DNA polymerase alpha catalytic subunit

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0022616	DNA strand elongation
0.49	GO:0006303	double-strand break repair via nonhomologous end joining
0.42	GO:0070914	UV-damage excision repair
0.41	GO:0008283	cell proliferation
0.39	GO:0016070	RNA metabolic process
0.36	GO:0006289	nucleotide-excision repair
0.36	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle

0.71	GO:0008408	3'-5' exonuclease activity
0.71	GO:0003887	DNA-directed DNA polymerase activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.64	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.50	GO:0046982	protein heterodimerization activity
0.41	GO:0003682	chromatin binding
0.39	GO:0019901	protein kinase binding

0.60	GO:0005634	nucleus
0.53	GO:0000428	DNA-directed RNA polymerase complex
0.53	GO:0030894	replisome
0.50	GO:0031974	membrane-enclosed lumen
0.48	GO:0005829	cytosol
0.40	GO:0000785	chromatin
0.39	GO:0012505	endomembrane system
0.37	GO:0031967	organelle envelope
0.35	GO:0016035	zeta DNA polymerase complex

0.71

GO:0003887

sp|O89043|DPOA2_RAT
DNA polymerase alpha subunit B
Search

POLA2

0.75	DNA polymerase alpha subunit B

0.65	GO:0071897	DNA biosynthetic process
0.64	GO:0006260	DNA replication
0.60	GO:0000060	protein import into nucleus, translocation
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0000723	telomere maintenance
0.34	GO:0019725	cellular homeostasis
0.33	GO:0048193	Golgi vesicle transport
0.33	GO:0043087	regulation of GTPase activity

0.69	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding

0.62	GO:0005658	alpha DNA polymerase:primase complex
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0003887

sp|O89044|PRI2_RAT
DNA primase large subunit
Search

PRIM2

0.72	DNA primase large subunit

0.73	GO:0006269	DNA replication, synthesis of RNA primer
0.44	GO:0071897	DNA biosynthetic process
0.36	GO:0032201	telomere maintenance via semi-conservative replication
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0006270	DNA replication initiation

0.75	GO:0003896	DNA primase activity
0.63	GO:0051539	4 iron, 4 sulfur cluster binding
0.51	GO:0046872	metal ion binding
0.50	GO:0003677	DNA binding
0.45	GO:0003887	DNA-directed DNA polymerase activity
0.35	GO:0005515	protein binding

0.51	GO:0005658	alpha DNA polymerase:primase complex
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.75

GO:0003896

sp|O89046|COR1B_RAT
Coronin-1B
Search

CORO1B

0.66

Coronin

0.71	GO:0030036	actin cytoskeleton organization
0.65	GO:2000394	positive regulation of lamellipodium morphogenesis
0.62	GO:1902463	protein localization to cell leading edge
0.62	GO:0071672	negative regulation of smooth muscle cell chemotaxis
0.60	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.59	GO:0035767	endothelial cell chemotaxis
0.59	GO:0031529	ruffle organization
0.58	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation
0.55	GO:0042060	wound healing
0.52	GO:0097435	supramolecular fiber organization

0.75	GO:0051015	actin filament binding
0.58	GO:0071933	Arp2/3 complex binding
0.56	GO:0045296	cadherin binding
0.52	GO:0042802	identical protein binding
0.44	GO:0048365	Rac GTPase binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.71	GO:0015629	actin cytoskeleton
0.59	GO:0030027	lamellipodium
0.54	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0099513	polymeric cytoskeletal fiber
0.49	GO:0005829	cytosol
0.45	GO:0016600	flotillin complex
0.45	GO:0016328	lateral plasma membrane
0.42	GO:0031982	vesicle
0.37	GO:0005925	focal adhesion
0.37	GO:0043230	extracellular organelle

0.34

GO:0008138

sp|O89047|KCNH3_RAT
Potassium voltage-gated channel subfamily H member 3
Search

KCNH3

0.93	Potassium voltage-gated channel subfamily H member 3

0.76	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.65	GO:0023014	signal transduction by protein phosphorylation
0.62	GO:0000160	phosphorelay signal transduction system
0.50	GO:0042391	regulation of membrane potential
0.33	GO:0007631	feeding behavior
0.33	GO:0007218	neuropeptide signaling pathway

0.77	GO:0005249	voltage-gated potassium channel activity
0.66	GO:0000155	phosphorelay sensor kinase activity
0.39	GO:0043855	cyclic nucleotide-gated ion channel activity
0.37	GO:0042802	identical protein binding
0.33	GO:0030551	cyclic nucleotide binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005887	integral component of plasma membrane
0.45	GO:0005622	intracellular
0.35	GO:0034705	potassium channel complex

0.66

GO:0000155

sp|O89049|TRXR1_RAT
Thioredoxin reductase 1, cytoplasmic
Search

TXNRD1

0.74	LOW QUALITY PROTEIN: thioredoxin reductase 1, cytoplasmic

0.68	GO:0098869	cellular oxidant detoxification
0.67	GO:0045454	cell redox homeostasis
0.59	GO:0022900	electron transport chain
0.53	GO:0001707	mesoderm formation
0.50	GO:0008283	cell proliferation
0.43	GO:0000305	response to oxygen radical
0.37	GO:0070276	halogen metabolic process
0.36	GO:0070995	NADPH oxidation
0.36	GO:0010269	response to selenium ion
0.36	GO:0071280	cellular response to copper ion

0.77	GO:0004791	thioredoxin-disulfide reductase activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.60	GO:0009055	electron transfer activity
0.54	GO:0015035	protein disulfide oxidoreductase activity
0.37	GO:0098623	selenite reductase activity
0.37	GO:0098626	methylseleninic acid reductase activity
0.37	GO:0098625	methylselenol reductase activity
0.36	GO:0033797	selenate reductase activity
0.36	GO:0016174	NAD(P)H oxidase activity
0.35	GO:0045340	mercury ion binding

0.54	GO:0001650	fibrillar center
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.35	GO:0043025	neuronal cell body
0.34	GO:0005783	endoplasmic reticulum
0.31	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:1.8.1.9	GO:0004791
0.77	KEGG:R02016	GO:0004791

sp|O89107|DNSL3_RAT
Deoxyribonuclease gamma
Search

DNASE1L3

0.63	Deoxyribonuclease gamma

0.76	GO:0006308	DNA catabolic process
0.62	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.60	GO:0002283	neutrophil activation involved in immune response
0.59	GO:0002673	regulation of acute inflammatory response
0.57	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0030262	apoptotic nuclear changes
0.55	GO:0010623	programmed cell death involved in cell development
0.38	GO:0002088	lens development in camera-type eye
0.38	GO:0060041	retina development in camera-type eye
0.34	GO:0003335	corneocyte development

0.71	GO:0004536	deoxyribonuclease activity
0.58	GO:0004519	endonuclease activity
0.35	GO:0003779	actin binding
0.35	GO:0003677	DNA binding
0.34	GO:0005509	calcium ion binding

0.48	GO:0005783	endoplasmic reticulum
0.46	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.34	GO:0031967	organelle envelope
0.34	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|O89117|DEFB1_RAT
Beta-defensin 1
Search

DEFB1

0.81	Beta-defensin 1

0.80	GO:0033574	response to testosterone
0.77	GO:0002526	acute inflammatory response
0.74	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.71	GO:0045087	innate immune response
0.71	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.69	GO:0009617	response to bacterium
0.67	GO:0019933	cAMP-mediated signaling
0.61	GO:0098542	defense response to other organism
0.60	GO:0002385	mucosal immune response
0.59	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

0.75	GO:0031731	CCR6 chemokine receptor binding
0.60	GO:0042802	identical protein binding

0.74	GO:1990742	microvesicle
0.71	GO:0097225	sperm midpiece
0.61	GO:0019898	extrinsic component of membrane
0.60	GO:0005615	extracellular space
0.40	GO:0005622	intracellular

sp|P00159|CYB_RAT
Cytochrome b
Search

CYTB

0.41	Cytochrome b

0.70	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.35	GO:0033590	response to cobalamin
0.35	GO:0033762	response to glucagon
0.35	GO:0055093	response to hyperoxia
0.35	GO:0031100	animal organ regeneration
0.35	GO:0042538	hyperosmotic salinity response
0.34	GO:0045471	response to ethanol
0.34	GO:0051592	response to calcium ion
0.34	GO:0046686	response to cadmium ion
0.34	GO:0001666	response to hypoxia

0.70	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding
0.34	GO:0032403	protein complex binding

0.69	GO:0045275	respiratory chain complex III
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.35	GO:0031301	integral component of organelle membrane

0.70

EC:1.10.2

GO:0016681

sp|P00173|CYB5_RAT
Cytochrome b5
Search

CYB5A

0.63	Microsomal cytochrome b5 type A

0.42	GO:0071466	cellular response to xenobiotic stimulus
0.39	GO:0046686	response to cadmium ion
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0006091	generation of precursor metabolites and energy
0.34	GO:0006631	fatty acid metabolic process
0.33	GO:1902600	hydrogen ion transmembrane transport

0.60	GO:0020037	heme binding
0.52	GO:0046872	metal ion binding
0.48	GO:0019899	enzyme binding
0.35	GO:0004768	stearoyl-CoA 9-desaturase activity
0.35	GO:0004033	aldo-keto reductase (NADP) activity
0.34	GO:0009055	electron transfer activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.41	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0098805	whole membrane
0.33	GO:0019867	outer membrane
0.33	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

0.35

EC:1.14.19.1

GO:0004768

sp|P00176|CP2B1_RAT
Cytochrome P450 2B1
Search

CYP2B

0.97	Testosterone 16a-hydroxylase type b

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0019373	epoxygenase P450 pathway
0.47	GO:0042738	exogenous drug catabolic process
0.44	GO:0006805	xenobiotic metabolic process
0.43	GO:0008202	steroid metabolic process
0.41	GO:0042180	cellular ketone metabolic process
0.38	GO:0014070	response to organic cyclic compound
0.37	GO:0051592	response to calcium ion
0.36	GO:0010477	response to sulfur dioxide
0.36	GO:0018933	nicotine metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.52	GO:0008392	arachidonic acid epoxygenase activity
0.50	GO:0008395	steroid hydroxylase activity
0.37	GO:0019825	oxygen binding
0.34	GO:0004721	phosphoprotein phosphatase activity

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P00185|CP1A1_RAT
Cytochrome P450 1A1
Search

sp|P00388|NCPR_RAT
NADPH--cytochrome P450 reductase
Search

POR

0.66	NADPH--cytochrome P450 reductase

0.55	GO:0090345	cellular organohalogen metabolic process
0.53	GO:0032770	positive regulation of monooxygenase activity
0.52	GO:0055114	oxidation-reduction process
0.40	GO:0043602	nitrate catabolic process
0.40	GO:0003420	regulation of growth plate cartilage chondrocyte proliferation
0.40	GO:0046210	nitric oxide catabolic process
0.39	GO:0045542	positive regulation of cholesterol biosynthetic process
0.39	GO:0090031	positive regulation of steroid hormone biosynthetic process
0.39	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.39	GO:0060192	negative regulation of lipase activity

0.81	GO:0003958	NADPH-hemoprotein reductase activity
0.69	GO:0010181	FMN binding
0.64	GO:0050661	NADP binding
0.61	GO:0050660	flavin adenine dinucleotide binding
0.40	GO:0047726	iron-cytochrome-c reductase activity
0.38	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
0.38	GO:0008941	nitric oxide dioxygenase activity
0.36	GO:0019899	enzyme binding
0.35	GO:0009055	electron transfer activity
0.34	GO:0016787	hydrolase activity

0.67	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.81

EC:1.6.2.4

GO:0003958

sp|P00406|COX2_RAT
Cytochrome c oxidase subunit 2
Search

COX2

0.44	Cytochrome c oxidase subunit 2

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.38	GO:0007595	lactation
0.37	GO:0009409	response to cold
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0045333	cellular respiration

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.49	GO:0070069	cytochrome complex
0.45	GO:0098796	membrane protein complex
0.35	GO:0098798	mitochondrial protein complex
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P00481|OTC_RAT
Ornithine carbamoyltransferase, mitochondrial
Search

OTC

0.45	Mitochondrial ornithine carbamoyltransferase

0.66	GO:0019240	citrulline biosynthetic process
0.65	GO:0000050	urea cycle
0.65	GO:0097272	ammonia homeostasis
0.63	GO:0006593	ornithine catabolic process
0.50	GO:0042450	arginine biosynthetic process via ornithine
0.44	GO:0070781	response to biotin
0.42	GO:0007494	midgut development
0.42	GO:0070207	protein homotrimerization
0.42	GO:0010043	response to zinc ion
0.41	GO:0001889	liver development

0.74	GO:0016743	carboxyl- or carbamoyltransferase activity
0.74	GO:0016597	amino acid binding
0.40	GO:0042301	phosphate ion binding
0.39	GO:0005543	phospholipid binding

0.49	GO:0005739	mitochondrion
0.48	GO:0019866	organelle inner membrane
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:2.1.3

GO:0016743

sp|P00502|GSTA1_RAT
Glutathione S-transferase alpha-1
Search

0.44	Glutathione S-transferase

0.47	GO:0006749	glutathione metabolic process
0.45	GO:0043651	linoleic acid metabolic process
0.45	GO:0060429	epithelium development
0.43	GO:0042221	response to chemical
0.42	GO:0046222	aflatoxin metabolic process
0.42	GO:0030154	cell differentiation
0.41	GO:1901377	organic heteropentacyclic compound catabolic process
0.40	GO:1901687	glutathione derivative biosynthetic process
0.39	GO:0001823	mesonephros development
0.39	GO:0007568	aging

0.76	GO:0004364	glutathione transferase activity
0.42	GO:0004602	glutathione peroxidase activity
0.40	GO:0043295	glutathione binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0008144	drug binding

0.46	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.40	GO:0005640	nuclear outer membrane

0.76

GO:0004364

sp|P00507|AATM_RAT
Aspartate aminotransferase, mitochondrial
Search

GOT2

0.49	Aspartate aminotransferase

0.59	GO:0006520	cellular amino acid metabolic process
0.53	GO:0043649	dicarboxylic acid catabolic process
0.52	GO:0045471	response to ethanol
0.50	GO:0015908	fatty acid transport
0.49	GO:0006103	2-oxoglutarate metabolic process
0.48	GO:0009058	biosynthetic process
0.46	GO:0006107	oxaloacetate metabolic process
0.46	GO:1901565	organonitrogen compound catabolic process
0.45	GO:0006106	fumarate metabolic process
0.41	GO:0042537	benzene-containing compound metabolic process

0.81	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.77	GO:0070546	L-phenylalanine aminotransferase activity
0.66	GO:0030170	pyridoxal phosphate binding
0.45	GO:0016212	kynurenine-oxoglutarate transaminase activity
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0016597	amino acid binding
0.37	GO:0005543	phospholipid binding
0.36	GO:0019899	enzyme binding
0.36	GO:0047578	4-hydroxyglutamate transaminase activity
0.34	GO:0003723	RNA binding

0.47	GO:0043209	myelin sheath
0.45	GO:0005739	mitochondrion
0.41	GO:0005886	plasma membrane
0.40	GO:0019866	organelle inner membrane
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0043204	perikaryon
0.38	GO:0009986	cell surface
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.81	EC:2.6.1.1	GO:0004069
0.81	KEGG:R00355	GO:0004069

sp|P00539|MOS_RAT
Proto-oncogene serine/threonine-protein kinase mos
Search

MOS

0.51	Serine/threonine-protein kinase-transforming protein mos

0.63	GO:0006468	protein phosphorylation
0.46	GO:1902103	negative regulation of metaphase/anaphase transition of meiotic cell cycle
0.45	GO:0051296	establishment of meiotic spindle orientation
0.43	GO:0043410	positive regulation of MAPK cascade
0.43	GO:0000212	meiotic spindle organization
0.42	GO:0043405	regulation of MAP kinase activity
0.42	GO:0032147	activation of protein kinase activity
0.42	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.40	GO:0006325	chromatin organization
0.39	GO:0035556	intracellular signal transduction

0.64	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005198	structural molecule activity
0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.35	GO:0005829	cytosol
0.35	GO:0019028	viral capsid
0.34	GO:0036338	viral membrane
0.33	GO:0015935	small ribosomal subunit

0.64

GO:0004674

sp|P00564|KCRM_RAT
Creatine kinase M-type
Search

CKM

0.92	Cytoplasmic creatine kinases

0.57	GO:0046314	phosphocreatine biosynthetic process
0.57	GO:0016310	phosphorylation
0.49	GO:0009408	response to heat
0.35	GO:0006600	creatine metabolic process

0.64	GO:0004111	creatine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.49	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.34	GO:0043209	myelin sheath
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.64	EC:2.7.3.2	GO:0004111
0.64	KEGG:R01881	GO:0004111

sp|P00684|RNS1B_RAT
Ribonuclease pancreatic beta-type
Search

RNASE1

0.91	Ribonuclease pancreatic alpha-type

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.46	GO:0016070	RNA metabolic process
0.36	GO:0051607	defense response to virus

0.66	GO:0004522	ribonuclease A activity
0.50	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding

0.51	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.30	GO:0044425	membrane part

0.66

EC:3.1.27.5

GO:0004522

sp|P00689|AMYP_RAT
Pancreatic alpha-amylase
Search

0.43	Pancreatic alpha-amylase

0.60	GO:0005975	carbohydrate metabolic process
0.37	GO:0007586	digestion
0.36	GO:1901575	organic substance catabolic process

0.81	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.80	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding
0.41	GO:0031404	chloride ion binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.41	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle

0.80

EC:3.2.1.1

GO:0004556

sp|P00697|LYSC1_RAT
Lysozyme C-1
Search

LYZ

0.55	Lysozyme C

0.77	GO:0042742	defense response to bacterium
0.77	GO:0019835	cytolysis
0.47	GO:0031640	killing of cells of other organism
0.44	GO:0016998	cell wall macromolecule catabolic process
0.41	GO:0007586	digestion
0.37	GO:0001895	retina homeostasis
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0019730	antimicrobial humoral response
0.34	GO:0006954	inflammatory response
0.33	GO:0044267	cellular protein metabolic process

0.78	GO:0003796	lysozyme activity
0.46	GO:0042802	identical protein binding
0.32	GO:0003735	structural constituent of ribosome

0.49	GO:0005576	extracellular region
0.36	GO:0030141	secretory granule
0.36	GO:0048237	rough endoplasmic reticulum lumen
0.35	GO:0000137	Golgi cis cisterna
0.35	GO:0005902	microvillus
0.35	GO:0030140	trans-Golgi network transport vesicle
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen
0.32	GO:0005840	ribosome

0.78

EC:3.2.1.17

GO:0003796

sp|P00714|LALBA_RAT
Alpha-lactalbumin
Search

LALBA

0.91	Alpha-lactalbumin protein variant D

0.86	GO:0005989	lactose biosynthetic process
0.45	GO:0050830	defense response to Gram-positive bacterium
0.45	GO:0050829	defense response to Gram-negative bacterium
0.44	GO:1903496	response to 11-deoxycorticosterone
0.44	GO:1903494	response to dehydroepiandrosterone
0.43	GO:0016998	cell wall macromolecule catabolic process
0.43	GO:0032570	response to progesterone
0.42	GO:0032355	response to estradiol
0.35	GO:0006915	apoptotic process
0.34	GO:0007267	cell-cell signaling

0.86	GO:0004461	lactose synthase activity
0.70	GO:0005509	calcium ion binding
0.44	GO:0003796	lysozyme activity
0.35	GO:0005515	protein binding

0.45	GO:0005576	extracellular region
0.36	GO:0005796	Golgi lumen
0.34	GO:0000139	Golgi membrane

0.86

EC:2.4.1.22

GO:0004461

sp|P00731|CBPA1_RAT
Carboxypeptidase A1
Search

CPA1

0.88	Carboxypeptidase A

0.59	GO:0006508	proteolysis
0.34	GO:0044257	cellular protein catabolic process

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.50

GO:0005615

extracellular space

0.76

EC:3.4.17

GO:0004181

sp|P00758|KLK1_RAT
Kallikrein-1
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.41	GO:0002675	positive regulation of acute inflammatory response
0.40	GO:0009405	pathogenesis
0.40	GO:0007584	response to nutrient
0.39	GO:0042127	regulation of cell proliferation
0.39	GO:0043065	positive regulation of apoptotic process
0.39	GO:0051604	protein maturation
0.38	GO:0008015	blood circulation
0.38	GO:0072376	protein activation cascade
0.37	GO:0035296	regulation of tube diameter

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.41	GO:0090729	toxin activity
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0008083	growth factor activity
0.34	GO:0046872	metal ion binding
0.32	GO:0019899	enzyme binding
0.32	GO:0016301	kinase activity

0.48	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.41	GO:0030141	secretory granule
0.40	GO:0097223	sperm part
0.40	GO:0005634	nucleus
0.40	GO:0045177	apical part of cell
0.39	GO:0043234	protein complex
0.33	GO:0009986	cell surface
0.33	GO:0005766	primary lysosome
0.33	GO:0060205	cytoplasmic vesicle lumen

0.69

GO:0004252

sp|P00759|KLK2_RAT
Tonin
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.42	GO:0002675	positive regulation of acute inflammatory response
0.40	GO:0007584	response to nutrient
0.40	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043065	positive regulation of apoptotic process
0.38	GO:0051604	protein maturation
0.38	GO:0008015	blood circulation
0.37	GO:0035296	regulation of tube diameter
0.37	GO:0003018	vascular process in circulatory system
0.37	GO:0002936	bradykinin biosynthetic process

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0090729	toxin activity
0.37	GO:0005102	receptor binding
0.36	GO:0030545	receptor regulator activity
0.35	GO:0046872	metal ion binding
0.34	GO:0019899	enzyme binding
0.33	GO:0043395	heparan sulfate proteoglycan binding
0.33	GO:0008201	heparin binding

0.48	GO:0005615	extracellular space
0.43	GO:0030141	secretory granule
0.41	GO:1903561	extracellular vesicle
0.40	GO:0005634	nucleus
0.40	GO:0097223	sperm part
0.40	GO:0045177	apical part of cell
0.40	GO:0043234	protein complex
0.36	GO:0005766	primary lysosome
0.36	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P00762|TRY1_RAT
Anionic trypsin-1
Search

0.77	Pancreatic anionic trypsinogen

0.61	GO:0006508	proteolysis
0.54	GO:0007586	digestion
0.40	GO:0030574	collagen catabolic process
0.38	GO:0031000	response to caffeine
0.38	GO:0007584	response to nutrient
0.38	GO:0043542	endothelial cell migration
0.38	GO:0035094	response to nicotine
0.36	GO:0022617	extracellular matrix disassembly
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0019730	antimicrobial humoral response

0.69	GO:0004252	serine-type endopeptidase activity
0.40	GO:0005509	calcium ion binding
0.35	GO:0097655	serpin family protein binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0004222	metalloendopeptidase activity

0.52	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.35	GO:0030141	secretory granule
0.35	GO:0097180	serine protease inhibitor complex
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0005766	primary lysosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0005775	vacuolar lumen
0.34	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P00763|TRY2_RAT
Anionic trypsin-2
Search

0.76	Pancreatic anionic trypsinogen

0.61	GO:0006508	proteolysis
0.54	GO:0007586	digestion
0.40	GO:0030574	collagen catabolic process
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.38	GO:0035094	response to nicotine
0.36	GO:0022617	extracellular matrix disassembly
0.36	GO:0043542	endothelial cell migration
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0019730	antimicrobial humoral response

0.69	GO:0004252	serine-type endopeptidase activity
0.40	GO:0005509	calcium ion binding
0.35	GO:0097655	serpin family protein binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0004222	metalloendopeptidase activity

0.52	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0097180	serine protease inhibitor complex
0.35	GO:0035578	azurophil granule lumen
0.34	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P00770|MCPT2_RAT
Mast cell protease 2
Search

0.97	Skeletal muscle neutral protease mekratin

0.61	GO:0006508	proteolysis
0.50	GO:0042222	interleukin-1 biosynthetic process
0.49	GO:0034769	basement membrane disassembly
0.48	GO:0032611	interleukin-1 beta production
0.47	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.44	GO:0001909	leukocyte mediated cytotoxicity
0.43	GO:0002228	natural killer cell mediated immunity
0.37	GO:0030901	midbrain development
0.37	GO:0071333	cellular response to glucose stimulus
0.37	GO:0019835	cytolysis

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0042277	peptide binding
0.36	GO:0008201	heparin binding
0.34	GO:1904854	proteasome core complex binding
0.33	GO:1990405	protein antigen binding
0.33	GO:0034185	apolipoprotein binding
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0004531	deoxyribonuclease II activity
0.33	GO:0019900	kinase binding
0.33	GO:0051087	chaperone binding

0.55	GO:0030141	secretory granule
0.44	GO:0005576	extracellular region
0.39	GO:0042629	mast cell granule
0.34	GO:0044194	cytolytic granule
0.34	GO:0010494	cytoplasmic stress granule
0.33	GO:0031232	extrinsic component of external side of plasma membrane
0.32	GO:0044218	other organism cell membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P00773|CELA1_RAT
Chymotrypsin-like elastase family member 1
Search

CELA1

0.92	Pancreatic elastase

0.61	GO:0006508	proteolysis
0.58	GO:0060309	elastin catabolic process
0.56	GO:0061113	pancreas morphogenesis
0.55	GO:0031017	exocrine pancreas development
0.53	GO:0035264	multicellular organism growth
0.53	GO:0048771	tissue remodeling
0.53	GO:0045766	positive regulation of angiogenesis
0.51	GO:0006954	inflammatory response
0.51	GO:0009791	post-embryonic development
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0008483	transaminase activity
0.32	GO:0030170	pyridoxal phosphate binding

0.45	GO:0005615	extracellular space
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P00774|CEL2A_RAT
Chymotrypsin-like elastase family member 2A
Search

0.85	Chymotrypsin C

0.61	GO:0006508	proteolysis
0.48	GO:0061436	establishment of skin barrier
0.36	GO:0008203	cholesterol metabolic process
0.35	GO:0070268	cornification
0.34	GO:0007596	blood coagulation
0.34	GO:0006874	cellular calcium ion homeostasis
0.33	GO:0009235	cobalamin metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.45	GO:0005615	extracellular space
0.43	GO:0036457	keratohyalin granule
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P00786|CATH_RAT
Pro-cathepsin H
Search

CTSH

0.97	Cathepsin H transcript variant 3

0.61	GO:0006508	proteolysis
0.59	GO:0010813	neuropeptide catabolic process
0.59	GO:0010815	bradykinin catabolic process
0.58	GO:0043129	surfactant homeostasis
0.58	GO:0097067	cellular response to thyroid hormone stimulus
0.57	GO:0060448	dichotomous subdivision of terminal units involved in lung branching
0.57	GO:0070371	ERK1 and ERK2 cascade
0.56	GO:0001913	T cell mediated cytotoxicity
0.56	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:0031648	protein destabilization

0.72	GO:0008234	cysteine-type peptidase activity
0.60	GO:0030108	HLA-A specific activating MHC class I receptor activity
0.59	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.57	GO:0070324	thyroid hormone binding
0.50	GO:0004177	aminopeptidase activity
0.47	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.32	GO:0030554	adenyl nucleotide binding

0.58	GO:0097208	alveolar lamellar body
0.53	GO:0005764	lysosome
0.52	GO:0036464	cytoplasmic ribonucleoprotein granule
0.51	GO:0005615	extracellular space
0.48	GO:0005829	cytosol
0.37	GO:1903561	extracellular vesicle
0.36	GO:0097486	multivesicular body lumen
0.36	GO:0001520	outer dense fiber
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen

0.72

GO:0008234

sp|P00787|CATB_RAT
Cathepsin B
Search

CTSB

0.82	Cathepsin B

0.68	GO:0050790	regulation of catalytic activity
0.61	GO:0006508	proteolysis
0.56	GO:0097067	cellular response to thyroid hormone stimulus
0.56	GO:0030574	collagen catabolic process
0.52	GO:0046697	decidualization
0.52	GO:0030855	epithelial cell differentiation
0.50	GO:0044257	cellular protein catabolic process
0.46	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.46	GO:0044409	entry into host
0.44	GO:0019058	viral life cycle

0.74	GO:0004197	cysteine-type endopeptidase activity
0.55	GO:0043394	proteoglycan binding
0.53	GO:0005518	collagen binding
0.36	GO:0030984	kininogen binding
0.35	GO:0043621	protein self-association
0.34	GO:0042277	peptide binding
0.33	GO:0004252	serine-type endopeptidase activity

0.53	GO:0005764	lysosome
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005615	extracellular space
0.49	GO:0005730	nucleolus
0.43	GO:0005739	mitochondrion
0.42	GO:0042470	melanosome
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031904	endosome lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0042383	sarcolemma

0.74

EC:3.4.22

GO:0004197

sp|P00884|ALDOB_RAT
Fructose-bisphosphate aldolase B
Search

ALDOB

0.54	Fructose-bisphosphate aldolase B

0.70	GO:0006096	glycolytic process
0.60	GO:0006116	NADH oxidation
0.57	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.56	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.56	GO:0006000	fructose metabolic process
0.55	GO:0032781	positive regulation of ATPase activity
0.37	GO:0001889	liver development
0.36	GO:0019320	hexose catabolic process
0.35	GO:0006735	NADH regeneration
0.35	GO:0070741	response to interleukin-6

0.78	GO:0004332	fructose-bisphosphate aldolase activity
0.63	GO:0061609	fructose-1-phosphate aldolase activity
0.61	GO:0070061	fructose binding
0.58	GO:0051117	ATPase binding
0.52	GO:0042802	identical protein binding
0.50	GO:0008092	cytoskeletal protein binding
0.35	GO:0031210	phosphatidylcholine binding
0.34	GO:0004707	MAP kinase activity

0.58	GO:0034451	centriolar satellite
0.37	GO:0070062	extracellular exosome
0.36	GO:0030868	smooth endoplasmic reticulum membrane
0.36	GO:0005829	cytosol
0.35	GO:0030867	rough endoplasmic reticulum membrane
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005764	lysosome
0.33	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78	EC:4.1.2.13	GO:0004332
0.34	KEGG:R00162	GO:0004707

sp|P01015|ANGT_RAT
Angiotensinogen
Search

AGT

0.95	Angiotensinogen

0.85	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.68	GO:1903598	positive regulation of gap junction assembly
0.68	GO:0010536	positive regulation of activation of Janus kinase activity
0.68	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway
0.67	GO:0010873	positive regulation of cholesterol esterification
0.66	GO:1901201	regulation of extracellular matrix assembly
0.66	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.66	GO:1903779	regulation of cardiac conduction
0.65	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.64	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway

0.71	GO:0031703	type 2 angiotensin receptor binding
0.69	GO:0031702	type 1 angiotensin receptor binding
0.48	GO:0004867	serine-type endopeptidase inhibitor activity
0.43	GO:0005179	hormone activity
0.37	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.37	GO:0017080	sodium channel regulator activity
0.36	GO:0008083	growth factor activity

0.73	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.35	GO:0005737	cytoplasm
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P01026|CO3_RAT
Complement C3
Search

0.90	Ophiophagus venom factor

0.84	GO:0006956	complement activation
0.74	GO:0010951	negative regulation of endopeptidase activity
0.66	GO:0006954	inflammatory response
0.58	GO:0001970	positive regulation of activation of membrane attack complex
0.58	GO:0002894	positive regulation of type II hypersensitivity
0.58	GO:0001796	regulation of type IIa hypersensitivity
0.58	GO:0010866	regulation of triglyceride biosynthetic process
0.57	GO:0097242	amyloid-beta clearance
0.57	GO:0010884	positive regulation of lipid storage
0.57	GO:2000427	positive regulation of apoptotic cell clearance

0.75	GO:0004866	endopeptidase inhibitor activity
0.61	GO:0031715	C5L2 anaphylatoxin chemotactic receptor binding
0.38	GO:0090729	toxin activity
0.36	GO:0005164	tumor necrosis factor receptor binding
0.35	GO:0004252	serine-type endopeptidase activity
0.35	GO:0008289	lipid binding
0.34	GO:0046872	metal ion binding
0.33	GO:0048037	cofactor binding
0.32	GO:0016491	oxidoreductase activity

0.73	GO:0005615	extracellular space
0.43	GO:0043234	protein complex
0.38	GO:1903561	extracellular vesicle
0.36	GO:0035578	azurophil granule lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004252

sp|P01039|CYTA_RAT
Cystatin-A
Search

CSTA

0.89	Cysteine protease inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.58	GO:0030216	keratinocyte differentiation
0.57	GO:0018149	peptide cross-linking
0.53	GO:0098609	cell-cell adhesion
0.40	GO:0008344	adult locomotory behavior
0.35	GO:0012501	programmed cell death
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0006508	proteolysis

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.60	GO:0002020	protease binding
0.56	GO:0030674	protein binding, bridging
0.47	GO:0005198	structural molecule activity
0.33	GO:0008233	peptidase activity
0.33	GO:0008168	methyltransferase activity

0.60	GO:0001533	cornified envelope
0.54	GO:0005615	extracellular space
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.40	GO:0031012	extracellular matrix
0.39	GO:1903561	extracellular vesicle
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.33

GO:0008233

sp|P01041|CYTB_RAT
Cystatin-B
Search

CSTB

0.96	Cystatin-B

0.76	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:0008344	adult locomotory behavior
0.36	GO:0043312	neutrophil degranulation
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.53	GO:0002020	protease binding
0.35	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0036094	small molecule binding

0.48	GO:0005730	nucleolus
0.48	GO:0005615	extracellular space
0.46	GO:0005829	cytosol
0.38	GO:1903561	extracellular vesicle
0.37	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.33	GO:0005840	ribosome

sp|P01048|KNT1_RAT
T-kininogen 1
Search

KNG1

0.94	High molecular weight kininogen II

0.76	GO:0010951	negative regulation of endopeptidase activity
0.63	GO:0030195	negative regulation of blood coagulation
0.60	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.55	GO:0007162	negative regulation of cell adhesion
0.48	GO:0042311	vasodilation
0.46	GO:0006954	inflammatory response
0.43	GO:0007596	blood coagulation
0.39	GO:0072376	protein activation cascade
0.38	GO:0002675	positive regulation of acute inflammatory response
0.37	GO:0010954	positive regulation of protein processing

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.53	GO:0005102	receptor binding
0.37	GO:0002020	protease binding
0.36	GO:0008201	heparin binding
0.34	GO:0008270	zinc ion binding

0.56	GO:0005615	extracellular space
0.54	GO:0031012	extracellular matrix
0.39	GO:1903561	extracellular vesicle
0.37	GO:0043204	perikaryon
0.37	GO:0031093	platelet alpha granule lumen
0.36	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005886	plasma membrane

sp|P01134|TGFA_RAT
Protransforming growth factor alpha
Search

TGFA

0.97	Protransforming growth factor alpha

0.61	GO:0072574	hepatocyte proliferation
0.61	GO:0007173	epidermal growth factor receptor signaling pathway
0.58	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.58	GO:0061377	mammary gland lobule development
0.58	GO:0008284	positive regulation of cell proliferation
0.55	GO:0001525	angiogenesis
0.50	GO:0000187	activation of MAPK activity
0.47	GO:0010469	regulation of receptor activity
0.45	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.45	GO:0051781	positive regulation of cell division

0.63	GO:0005154	epidermal growth factor receptor binding
0.48	GO:0008083	growth factor activity

0.48	GO:0005615	extracellular space
0.43	GO:0005887	integral component of plasma membrane
0.40	GO:0016323	basolateral plasma membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0009986	cell surface
0.39	GO:0031410	cytoplasmic vesicle
0.37	GO:0005634	nucleus
0.37	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0012506	vesicle membrane
0.35	GO:0000139	Golgi membrane

sp|P01143|CRF_RAT
Corticoliberin
Search

CRH

0.97	Corticotropin releasing hormone b

0.76	GO:0010469	regulation of receptor activity
0.64	GO:2000851	positive regulation of glucocorticoid secretion
0.64	GO:0051461	positive regulation of corticotropin secretion
0.64	GO:0051462	regulation of cortisol secretion
0.62	GO:0001963	synaptic transmission, dopaminergic
0.61	GO:1900449	regulation of glutamate receptor signaling pathway
0.61	GO:2001025	positive regulation of response to drug
0.60	GO:0006704	glucocorticoid biosynthetic process
0.59	GO:2001257	regulation of cation channel activity
0.59	GO:0035641	locomotory exploration behavior

0.79	GO:0005179	hormone activity
0.45	GO:0051430	corticotropin-releasing hormone receptor 1 binding
0.44	GO:0051431	corticotropin-releasing hormone receptor 2 binding
0.33	GO:0004601	peroxidase activity
0.33	GO:0004849	uridine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.66	GO:0005576	extracellular region
0.44	GO:0043196	varicosity
0.43	GO:0043204	perikaryon
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33	EC:1.11.1.7	GO:0004601
0.33	KEGG:R03532	GO:0004601

sp|P01150|TRH_RAT
Pro-thyrotropin-releasing hormone
Search

TRH

0.78	Pro-thyrotropin-releasing hormone

0.77	GO:0009755	hormone-mediated signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0014050	negative regulation of glutamate secretion
0.57	GO:0014054	positive regulation of gamma-aminobutyric acid secretion
0.56	GO:0001692	histamine metabolic process
0.55	GO:0007628	adult walking behavior
0.55	GO:0042755	eating behavior
0.54	GO:0032024	positive regulation of insulin secretion
0.50	GO:0051412	response to corticosterone
0.50	GO:2000252	negative regulation of feeding behavior

0.87

GO:0008437

thyrotropin-releasing hormone activity

0.66	GO:0005576	extracellular region
0.51	GO:0030141	secretory granule
0.43	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane

sp|P01159|SCOTP_RAT
Scotophobin
Search

sp|P01161|ANF_RAT
Natriuretic peptides A
Search

NPPA

0.97	Atrial natriuretic peptide hormone

0.77	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.67	GO:0007168	receptor guanylyl cyclase signaling pathway
0.67	GO:1903766	positive regulation of potassium ion export across plasma membrane
0.65	GO:1902261	positive regulation of delayed rectifier potassium channel activity
0.65	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization
0.64	GO:0060452	positive regulation of cardiac muscle contraction
0.63	GO:0010460	positive regulation of heart rate
0.62	GO:0007565	female pregnancy
0.62	GO:0006182	cGMP biosynthetic process

0.79	GO:0005179	hormone activity
0.62	GO:0071855	neuropeptide receptor binding
0.60	GO:0051427	hormone receptor binding

0.66	GO:0005576	extracellular region
0.46	GO:0043234	protein complex
0.42	GO:0042629	mast cell granule
0.40	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P01174|WAP_RAT
Whey acidic protein
Search

WAP

0.80	Whey acidic protein (Fragment)

0.76	GO:0010466	negative regulation of peptidase activity
0.39	GO:0042742	defense response to bacterium
0.37	GO:0052548	regulation of endopeptidase activity
0.36	GO:0006468	protein phosphorylation

0.76	GO:0030414	peptidase inhibitor activity
0.40	GO:0045735	nutrient reservoir activity
0.38	GO:0061135	endopeptidase regulator activity
0.36	GO:0004672	protein kinase activity

0.66	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P01179|NEU1_RAT
Oxytocin-neurophysin 1
Search

OXT

0.96	Prepropeptide for oxytocin and neurophysin

0.76	GO:0010469	regulation of receptor activity
0.51	GO:0032094	response to food
0.49	GO:0070528	protein kinase C signaling
0.49	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.49	GO:0070371	ERK1 and ERK2 cascade
0.48	GO:0009612	response to mechanical stimulus
0.48	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.48	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.45	GO:0006915	apoptotic process
0.45	GO:0002125	maternal aggressive behavior

0.86	GO:0005185	neurohypophyseal hormone activity
0.52	GO:0031894	V1A vasopressin receptor binding
0.49	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.43	GO:0031855	oxytocin receptor binding
0.41	GO:0004871	signal transducer activity
0.41	GO:0004672	protein kinase activity
0.39	GO:0031895	V1B vasopressin receptor binding
0.36	GO:0031896	V2 vasopressin receptor binding
0.33	GO:0052795	exo-alpha-(2->6)-sialidase activity
0.33	GO:0052796	exo-alpha-(2->8)-sialidase activity

0.66	GO:0005576	extracellular region
0.43	GO:0043005	neuron projection
0.43	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0030141	secretory granule
0.40	GO:0036477	somatodendritic compartment
0.39	GO:0098793	presynapse
0.38	GO:0044297	cell body
0.34	GO:0030665	clathrin-coated vesicle membrane
0.33	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.33

EC:3.2.1.18

GO:0052795

sp|P01186|NEU2_RAT
Vasopressin-neurophysin 2-copeptin
Search

0.96	Prepropeptide for oxytocin and neurophysin

0.76	GO:0010469	regulation of receptor activity
0.52	GO:0070528	protein kinase C signaling
0.52	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.51	GO:0070371	ERK1 and ERK2 cascade
0.50	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.50	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.49	GO:0032094	response to food
0.47	GO:0006915	apoptotic process
0.46	GO:0009612	response to mechanical stimulus
0.45	GO:0008015	blood circulation

0.86	GO:0005185	neurohypophyseal hormone activity
0.55	GO:0031894	V1A vasopressin receptor binding
0.51	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.42	GO:0004871	signal transducer activity
0.42	GO:0004672	protein kinase activity
0.42	GO:0031855	oxytocin receptor binding
0.42	GO:0031895	V1B vasopressin receptor binding
0.37	GO:0031896	V2 vasopressin receptor binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0052795	exo-alpha-(2->6)-sialidase activity

0.66	GO:0005576	extracellular region
0.43	GO:0043005	neuron projection
0.43	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0030141	secretory granule
0.41	GO:0036477	somatodendritic compartment
0.38	GO:0044297	cell body
0.38	GO:0098793	presynapse
0.35	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.33	EC:3.2.1.18	GO:0052795
0.33	KEGG:R03876	GO:0004842

sp|P01194|COLI_RAT
Pro-opiomelanocortin
Search

POMC

0.57	Proopiomelanocortin (Adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)

0.75	GO:0010469	regulation of receptor activity
0.59	GO:2000852	regulation of corticosterone secretion
0.55	GO:0032098	regulation of appetite
0.55	GO:0032720	negative regulation of tumor necrosis factor production
0.55	GO:0070873	regulation of glycogen metabolic process
0.54	GO:0033059	cellular pigmentation
0.53	GO:0008217	regulation of blood pressure
0.52	GO:0042593	glucose homeostasis
0.50	GO:0007267	cell-cell signaling
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II

0.78	GO:0005179	hormone activity
0.58	GO:0070996	type 1 melanocortin receptor binding
0.58	GO:0031781	type 3 melanocortin receptor binding
0.58	GO:0031782	type 4 melanocortin receptor binding

0.66	GO:0005576	extracellular region
0.53	GO:0030141	secretory granule
0.36	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0031907	microbody lumen
0.35	GO:0044439	peroxisomal part

sp|P01230|LSHB_RAT
Lutropin subunit beta
Search

LHB

0.91	LOW QUALITY PROTEIN: lutropin subunit beta

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0030728	ovulation
0.52	GO:0009755	hormone-mediated signaling pathway
0.52	GO:0007267	cell-cell signaling
0.49	GO:0007186	G-protein coupled receptor signaling pathway
0.44	GO:0030823	regulation of cGMP metabolic process
0.40	GO:0006701	progesterone biosynthetic process
0.38	GO:0009914	hormone transport
0.38	GO:0016486	peptide hormone processing
0.38	GO:0008584	male gonad development

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.39	GO:0031982	vesicle
0.39	GO:0005737	cytoplasm
0.36	GO:0012505	endomembrane system
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P01237|PRL_RAT
Prolactin
Search

PRL

0.90	prolactin precursor

0.75	GO:0010469	regulation of receptor activity
0.54	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.54	GO:0001937	negative regulation of endothelial cell proliferation
0.53	GO:0046427	positive regulation of JAK-STAT cascade
0.52	GO:0040014	regulation of multicellular organism growth
0.51	GO:0007595	lactation
0.45	GO:0030072	peptide hormone secretion
0.44	GO:0045723	positive regulation of fatty acid biosynthetic process
0.42	GO:0043066	negative regulation of apoptotic process
0.40	GO:1903489	positive regulation of lactation

0.79	GO:0005179	hormone activity
0.48	GO:0005148	prolactin receptor binding
0.35	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.38	GO:0030141	secretory granule
0.35	GO:0031904	endosome lumen
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P01244|SOMA_RAT
Somatotropin
Search

0.76	somatotropin precursor

0.76	GO:0010469	regulation of receptor activity
0.56	GO:1903408	positive regulation of sodium:potassium-exchanging ATPase activity
0.56	GO:0030073	insulin secretion
0.55	GO:0032930	positive regulation of superoxide anion generation
0.54	GO:0032094	response to food
0.53	GO:0010960	magnesium ion homeostasis
0.53	GO:0055078	sodium ion homeostasis
0.53	GO:0042538	hyperosmotic salinity response
0.50	GO:0040018	positive regulation of multicellular organism growth
0.50	GO:0055074	calcium ion homeostasis

0.85	GO:0005131	growth hormone receptor binding
0.79	GO:0005179	hormone activity
0.40	GO:0046872	metal ion binding
0.36	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process
0.35	GO:0005148	prolactin receptor binding
0.35	GO:0004346	glucose-6-phosphatase activity
0.34	GO:0008083	growth factor activity
0.33	GO:0004888	transmembrane signaling receptor activity

0.73	GO:0005615	extracellular space
0.48	GO:0030141	secretory granule
0.48	GO:0005802	trans-Golgi network
0.41	GO:0005634	nucleus
0.39	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0070195	growth hormone receptor complex
0.35	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.3.9	GO:0004346
0.35	KEGG:R00303	GO:0004346

sp|P01257|CALC_RAT
Calcitonin
Search

CALCA

0.93	Salmon calcitonin-V

0.76	GO:0010469	regulation of receptor activity
0.67	GO:0001984	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
0.64	GO:0031645	negative regulation of neurological system process
0.64	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.64	GO:0045779	negative regulation of bone resorption
0.63	GO:0045986	negative regulation of smooth muscle contraction
0.63	GO:0007190	activation of adenylate cyclase activity
0.63	GO:1990090	cellular response to nerve growth factor stimulus
0.62	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.62	GO:0048265	response to pain

0.79	GO:0005179	hormone activity
0.67	GO:0031716	calcitonin receptor binding
0.54	GO:0042802	identical protein binding
0.41	GO:0032403	protein complex binding

0.66	GO:0005576	extracellular region
0.61	GO:0043195	terminal bouton
0.58	GO:0043025	neuronal cell body
0.41	GO:0005737	cytoplasm
0.40	GO:0005634	nucleus

sp|P01283|VIP_RAT
VIP peptides
Search

VIP

0.97	Vasoactive intestinal polypeptide

0.76	GO:0070459	prolactin secretion
0.76	GO:0010469	regulation of receptor activity
0.72	GO:0048255	mRNA stabilization
0.60	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.60	GO:0019933	cAMP-mediated signaling
0.54	GO:0045732	positive regulation of protein catabolic process
0.54	GO:0032880	regulation of protein localization
0.44	GO:0007218	neuropeptide signaling pathway
0.43	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.43	GO:0010562	positive regulation of phosphorus metabolic process

0.79	GO:0005179	hormone activity
0.43	GO:0051428	peptide hormone receptor binding
0.36	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding
0.36	GO:0005057	signal transducer activity, downstream of receptor

0.66	GO:0005576	extracellular region
0.38	GO:0005622	intracellular
0.38	GO:0097458	neuron part
0.37	GO:0044297	cell body
0.36	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0044456	synapse part
0.34	GO:0044463	cell projection part
0.30	GO:0016020	membrane

sp|P01322|INS1_RAT
Insulin-1
Search

INS

0.95

Insulin

0.76	GO:0010469	regulation of receptor activity
0.70	GO:0006006	glucose metabolic process
0.50	GO:0045818	negative regulation of glycogen catabolic process
0.50	GO:0010243	response to organonitrogen compound
0.50	GO:0050995	negative regulation of lipid catabolic process
0.50	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.50	GO:1902952	positive regulation of dendritic spine maintenance
0.50	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.49	GO:0046628	positive regulation of insulin receptor signaling pathway
0.49	GO:0002674	negative regulation of acute inflammatory response

0.79	GO:0005179	hormone activity
0.53	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0005158	insulin receptor binding
0.49	GO:0002020	protease binding
0.44	GO:0042802	identical protein binding
0.37	GO:0051087	chaperone binding

0.66	GO:0005576	extracellular region
0.42	GO:0030141	secretory granule
0.39	GO:0060205	cytoplasmic vesicle lumen
0.37	GO:0005829	cytosol
0.37	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0031904	endosome lumen
0.36	GO:0005796	Golgi lumen
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0030133	transport vesicle

sp|P01323|INS2_RAT
Insulin-2
Search

INS

0.95

Insulin

0.76	GO:0010469	regulation of receptor activity
0.71	GO:0006006	glucose metabolic process
0.50	GO:0045818	negative regulation of glycogen catabolic process
0.50	GO:0010243	response to organonitrogen compound
0.50	GO:0050995	negative regulation of lipid catabolic process
0.50	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.50	GO:1902952	positive regulation of dendritic spine maintenance
0.50	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.49	GO:2000252	negative regulation of feeding behavior
0.49	GO:0046628	positive regulation of insulin receptor signaling pathway

0.79	GO:0005179	hormone activity
0.53	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0005158	insulin receptor binding
0.49	GO:0002020	protease binding
0.44	GO:0042802	identical protein binding
0.36	GO:0051087	chaperone binding

0.66	GO:0005576	extracellular region
0.42	GO:0030141	secretory granule
0.39	GO:0060205	cytoplasmic vesicle lumen
0.37	GO:0005829	cytosol
0.37	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0031904	endosome lumen
0.36	GO:0005796	Golgi lumen
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005634	nucleus

sp|P01346|IGF2_RAT
Insulin-like growth factor II
Search

IGF2

0.94	Insulin like growth factor 2

0.75	GO:0010469	regulation of receptor activity
0.54	GO:0046628	positive regulation of insulin receptor signaling pathway
0.53	GO:0042104	positive regulation of activated T cell proliferation
0.52	GO:0051897	positive regulation of protein kinase B signaling
0.51	GO:0045840	positive regulation of mitotic nuclear division
0.49	GO:0043410	positive regulation of MAPK cascade
0.44	GO:0060669	embryonic placenta morphogenesis
0.44	GO:0032868	response to insulin
0.44	GO:0051781	positive regulation of cell division
0.44	GO:0051147	regulation of muscle cell differentiation

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.54	GO:0005159	insulin-like growth factor receptor binding
0.53	GO:0005158	insulin receptor binding
0.39	GO:0043539	protein serine/threonine kinase activator activity
0.34	GO:0004511	tyrosine 3-monooxygenase activity
0.32	GO:0005506	iron ion binding

0.73	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0031093	platelet alpha granule lumen
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:1.14.16.2

GO:0004511

sp|P01347|REL1_RAT
Prorelaxin 1
Search

RLN1

0.97	Prorelaxin

0.76	GO:0010469	regulation of receptor activity
0.72	GO:0060618	nipple development
0.70	GO:0010749	regulation of nitric oxide mediated signal transduction
0.69	GO:0060736	prostate gland growth
0.67	GO:0060443	mammary gland morphogenesis
0.63	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.62	GO:0007283	spermatogenesis
0.58	GO:0042981	regulation of apoptotic process
0.54	GO:0050878	regulation of body fluid levels
0.53	GO:0043069	negative regulation of programmed cell death

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P01355|CCKN_RAT
Cholecystokinin
Search

CCK

0.97	Preprocholecystokinin

0.76	GO:0010469	regulation of receptor activity
0.60	GO:0042755	eating behavior
0.58	GO:0001764	neuron migration
0.56	GO:0007409	axonogenesis
0.43	GO:0031667	response to nutrient levels
0.43	GO:0014049	positive regulation of glutamate secretion
0.43	GO:0051901	positive regulation of mitochondrial depolarization
0.42	GO:0051930	regulation of sensory perception of pain
0.42	GO:0001836	release of cytochrome c from mitochondria
0.42	GO:0032096	negative regulation of response to food

0.79	GO:0005179	hormone activity
0.33	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.56	GO:0030424	axon
0.41	GO:0043204	perikaryon
0.41	GO:0043679	axon terminus
0.40	GO:0030425	dendrite
0.30	GO:0031224	intrinsic component of membrane

sp|P01581|IFNG_RAT
Interferon gamma
Search

IFNG

0.77	Interferon gamma

0.74	GO:0006955	immune response
0.72	GO:0040008	regulation of growth
0.72	GO:0051607	defense response to virus
0.70	GO:0010469	regulation of receptor activity
0.54	GO:0060552	positive regulation of fructose 1,6-bisphosphate metabolic process
0.54	GO:0060550	positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity
0.54	GO:0032834	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
0.54	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.54	GO:0010508	positive regulation of autophagy
0.54	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity

0.86	GO:0005133	interferon-gamma receptor binding
0.74	GO:0005125	cytokine activity

0.68	GO:0005615	extracellular space
0.49	GO:0043204	perikaryon
0.47	GO:0009897	external side of plasma membrane
0.46	GO:0043005	neuron projection
0.36	GO:0005737	cytoplasm

sp|P01681|KVX01_RAT
Ig kappa chain V region S211
Search

0.91	Ig kappa chain V-I region Walker

0.75	GO:0002377	immunoglobulin production
0.69	GO:0006955	immune response
0.55	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.55	GO:0038095	Fc-epsilon receptor signaling pathway
0.54	GO:0030449	regulation of complement activation
0.52	GO:0002449	lymphocyte mediated immunity
0.52	GO:0072376	protein activation cascade
0.52	GO:0050900	leukocyte migration
0.47	GO:0006898	receptor-mediated endocytosis
0.43	GO:0006508	proteolysis

0.64	GO:0003823	antigen binding
0.46	GO:0004252	serine-type endopeptidase activity
0.36	GO:0042802	identical protein binding
0.36	GO:0003964	RNA-directed DNA polymerase activity

0.68	GO:0005615	extracellular space
0.47	GO:1903561	extracellular vesicle
0.43	GO:0005886	plasma membrane
0.42	GO:0071745	IgA immunoglobulin complex
0.42	GO:0071753	IgM immunoglobulin complex
0.30	GO:0016021	integral component of membrane

0.46

GO:0004252

sp|P01805|HVR01_RAT
Ig heavy chain V region IR2
Search

0.71	Anti-staphylococcal enterotoxin D heavy chain variable region (Fragment)

0.72	GO:0006910	phagocytosis, recognition
0.72	GO:0006958	complement activation, classical pathway
0.72	GO:0006911	phagocytosis, engulfment
0.72	GO:0050853	B cell receptor signaling pathway
0.71	GO:0050871	positive regulation of B cell activation
0.66	GO:0045087	innate immune response
0.65	GO:0042742	defense response to bacterium
0.39	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.39	GO:0038095	Fc-epsilon receptor signaling pathway
0.38	GO:0030449	regulation of complement activation

0.84	GO:0003823	antigen binding
0.73	GO:0034987	immunoglobulin receptor binding
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0042571	immunoglobulin complex, circulating
0.72	GO:0072562	blood microparticle
0.68	GO:0009897	external side of plasma membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.36

GO:0004252

sp|P01830|THY1_RAT
Thy-1 membrane glycoprotein
Search

THY1

0.96	Thy-1 cell surface antigen

0.79	GO:0030334	regulation of cell migration
0.72	GO:0007155	cell adhesion
0.67	GO:0046549	retinal cone cell development
0.66	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity
0.66	GO:0050860	negative regulation of T cell receptor signaling pathway
0.65	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.65	GO:0051894	positive regulation of focal adhesion assembly
0.63	GO:0010977	negative regulation of neuron projection development
0.62	GO:0070570	regulation of neuron projection regeneration
0.61	GO:0001525	angiogenesis

0.84	GO:0005178	integrin binding
0.57	GO:0034235	GPI anchor binding
0.50	GO:0005096	GTPase activator activity
0.48	GO:0019901	protein kinase binding
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.64	GO:0031362	anchored component of external side of plasma membrane
0.60	GO:0043209	myelin sheath
0.60	GO:0016324	apical plasma membrane
0.59	GO:0030425	dendrite
0.59	GO:0098857	membrane microdomain
0.53	GO:0005783	endoplasmic reticulum
0.49	GO:0030426	growth cone
0.43	GO:0032809	neuronal cell body membrane
0.43	GO:0030673	axolemma
0.39	GO:0005829	cytosol

0.35

EC:3.4.19.12

GO:0036459

sp|P01835|KACB_RAT
Ig kappa chain C region, B allele
Search

IGKC

0.92	Ig kappa chain C region

0.64	GO:0002250	adaptive immune response
0.62	GO:0006910	phagocytosis, recognition
0.61	GO:0006911	phagocytosis, engulfment
0.61	GO:0050853	B cell receptor signaling pathway
0.60	GO:0030183	B cell differentiation
0.60	GO:0050871	positive regulation of B cell activation
0.60	GO:0002449	lymphocyte mediated immunity
0.60	GO:0006956	complement activation
0.57	GO:0045087	innate immune response
0.56	GO:0042742	defense response to bacterium

0.78	GO:0003823	antigen binding
0.62	GO:0034987	immunoglobulin receptor binding
0.43	GO:0046872	metal ion binding

0.62	GO:0042571	immunoglobulin complex, circulating
0.61	GO:0072562	blood microparticle
0.58	GO:0009897	external side of plasma membrane
0.50	GO:0070062	extracellular exosome

sp|P01836|KACA_RAT
Ig kappa chain C region, A allele
Search

IGKC

0.95	Immunoglobulin kappa constant

0.70	GO:0002250	adaptive immune response
0.69	GO:0006910	phagocytosis, recognition
0.69	GO:0006911	phagocytosis, engulfment
0.69	GO:0050853	B cell receptor signaling pathway
0.68	GO:0050871	positive regulation of B cell activation
0.67	GO:0002449	lymphocyte mediated immunity
0.67	GO:0006956	complement activation
0.63	GO:0045087	innate immune response
0.63	GO:0042742	defense response to bacterium
0.59	GO:0030183	B cell differentiation

0.79	GO:0003823	antigen binding
0.70	GO:0034987	immunoglobulin receptor binding
0.42	GO:0004252	serine-type endopeptidase activity
0.42	GO:0046872	metal ion binding

0.69	GO:0042571	immunoglobulin complex, circulating
0.69	GO:0072562	blood microparticle
0.65	GO:0009897	external side of plasma membrane
0.55	GO:0070062	extracellular exosome

0.42

GO:0004252

sp|P01855|IGHE_RAT
Ig epsilon chain C region
Search

IGHE

0.95	Immunoglobulin heavy constant epsilon

0.73	GO:0006910	phagocytosis, recognition
0.72	GO:0006911	phagocytosis, engulfment
0.72	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.72	GO:0050853	B cell receptor signaling pathway
0.71	GO:0050871	positive regulation of B cell activation
0.70	GO:0006956	complement activation
0.66	GO:0045087	innate immune response
0.66	GO:0042742	defense response to bacterium
0.45	GO:0038093	Fc receptor signaling pathway
0.43	GO:0002673	regulation of acute inflammatory response

0.77	GO:0003823	antigen binding
0.74	GO:0034987	immunoglobulin receptor binding
0.37	GO:0004252	serine-type endopeptidase activity

0.73	GO:0042571	immunoglobulin complex, circulating
0.72	GO:0072562	blood microparticle
0.68	GO:0009897	external side of plasma membrane
0.40	GO:0070062	extracellular exosome
0.36	GO:0005771	multivesicular body
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.37

GO:0004252

sp|P01883|IGHD_RAT
Ig delta chain C region (Fragment)
Search

IGHD

0.97	Ig delta chain C region membrane-bound form

0.69	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.66	GO:0006955	immune response
0.52	GO:0016446	somatic hypermutation of immunoglobulin genes
0.51	GO:0030890	positive regulation of B cell proliferation
0.49	GO:0002449	lymphocyte mediated immunity
0.46	GO:0050776	regulation of immune response
0.44	GO:0006910	phagocytosis, recognition
0.44	GO:0006911	phagocytosis, engulfment
0.43	GO:0072376	protein activation cascade
0.42	GO:0048584	positive regulation of response to stimulus

0.64	GO:0003823	antigen binding
0.44	GO:0034987	immunoglobulin receptor binding
0.41	GO:0042802	identical protein binding
0.37	GO:0023026	MHC class II protein complex binding

0.64	GO:0042613	MHC class II protein complex
0.52	GO:0019815	B cell receptor complex
0.49	GO:0009897	external side of plasma membrane
0.44	GO:0042571	immunoglobulin complex, circulating
0.44	GO:0072562	blood microparticle
0.36	GO:0031902	late endosome membrane
0.36	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

sp|P01946|HBA_RAT
Hemoglobin subunit alpha-1/2
Search

HBA

0.80	Hemoglobin subunit alpha

0.79	GO:0015671	oxygen transport
0.38	GO:0051291	protein heterooligomerization
0.37	GO:0048821	erythrocyte development
0.36	GO:0042542	response to hydrogen peroxide
0.36	GO:0001701	in utero embryonic development
0.36	GO:0010942	positive regulation of cell death
0.36	GO:0042744	hydrogen peroxide catabolic process
0.36	GO:0014070	response to organic cyclic compound
0.35	GO:0051930	regulation of sensory perception of pain
0.35	GO:0045776	negative regulation of blood pressure

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.38	GO:0031720	haptoglobin binding
0.35	GO:0004601	peroxidase activity
0.35	GO:0001540	amyloid-beta binding
0.33	GO:0043177	organic acid binding

0.83	GO:0005833	hemoglobin complex
0.38	GO:0031838	haptoglobin-hemoglobin complex
0.37	GO:0072562	blood microparticle
0.36	GO:0070062	extracellular exosome
0.36	GO:0022627	cytosolic small ribosomal subunit
0.35	GO:0043209	myelin sheath
0.34	GO:0045202	synapse
0.30	GO:0016020	membrane

0.35	EC:1.11.1.7	GO:0004601
0.35	KEGG:R03532	GO:0004601

sp|P02091|HBB1_RAT
Hemoglobin subunit beta-1
Search

0.81	Hemoglobin beta chain subunit

0.79	GO:0015671	oxygen transport
0.42	GO:0070293	renal absorption
0.41	GO:0051291	protein heterooligomerization
0.41	GO:0042542	response to hydrogen peroxide
0.40	GO:0010942	positive regulation of cell death
0.39	GO:0042744	hydrogen peroxide catabolic process
0.39	GO:0098869	cellular oxidant detoxification
0.38	GO:0048821	erythrocyte development
0.38	GO:0010999	regulation of eIF2 alpha phosphorylation by heme
0.37	GO:0070527	platelet aggregation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0031720	haptoglobin binding
0.43	GO:0030492	hemoglobin binding
0.39	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.45	GO:0031838	haptoglobin-hemoglobin complex
0.41	GO:0005615	extracellular space
0.36	GO:0043209	myelin sheath
0.36	GO:1903561	extracellular vesicle
0.35	GO:0071682	endocytic vesicle lumen
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen

0.39	EC:1.11.1.7	GO:0004601
0.39	KEGG:R03532	GO:0004601

sp|P02262|H2A1_RAT
Histone H2A type 1
Search

sp|P02317|STP1_RAT
Spermatid nuclear transition protein 1
Search

TNP1

0.97	Spermatid nuclear transition protein 1

0.80	GO:0007283	spermatogenesis
0.75	GO:0000012	single strand break repair
0.73	GO:0031498	chromatin disassembly
0.73	GO:0032986	protein-DNA complex disassembly
0.72	GO:0030317	flagellated sperm motility
0.72	GO:0010954	positive regulation of protein processing
0.70	GO:0006997	nucleus organization
0.69	GO:0006342	chromatin silencing
0.69	GO:0043486	histone exchange
0.69	GO:0007281	germ cell development

0.55	GO:0003677	DNA binding
0.35	GO:0005515	protein binding

0.75	GO:0000786	nucleosome
0.62	GO:0000790	nuclear chromatin
0.57	GO:0001673	male germ cell nucleus

sp|P02401|RLA2_RAT
60S acidic ribosomal protein P2
Search

RPLP2

0.79	Renal carcinoma antigen NY-REN-44

0.69	GO:0006414	translational elongation
0.46	GO:0002181	cytoplasmic translation
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0043009	chordate embryonic development
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0042254	ribosome biogenesis
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0045727	positive regulation of translation
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0030218	erythrocyte differentiation

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0005506	iron ion binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P02454|CO1A1_RAT
Collagen alpha-1(I) chain
Search

COL1A1

0.82	Collagen type II alpha 1 chain

0.60	GO:0030199	collagen fibril organization
0.60	GO:0001958	endochondral ossification
0.60	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.58	GO:0048706	embryonic skeletal system development
0.58	GO:0007605	sensory perception of sound
0.57	GO:0032964	collagen biosynthetic process
0.57	GO:0034505	tooth mineralization
0.57	GO:0043589	skin morphogenesis
0.56	GO:0001957	intramembranous ossification
0.56	GO:0060346	bone trabecula formation

0.77	GO:0005201	extracellular matrix structural constituent
0.62	GO:0048407	platelet-derived growth factor binding
0.54	GO:0002020	protease binding
0.53	GO:0042802	identical protein binding
0.49	GO:0042289	MHC class II protein binding
0.36	GO:0046872	metal ion binding

0.72	GO:0005581	collagen trimer
0.62	GO:0098643	banded collagen fibril
0.55	GO:0005615	extracellular space
0.46	GO:0005604	basement membrane
0.40	GO:0005737	cytoplasm
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P02466|CO1A2_RAT
Collagen alpha-2(I) chain
Search

COL1A2

0.86	Collagen type II alpha 1 chain

0.66	GO:0043589	skin morphogenesis
0.66	GO:0070208	protein heterotrimerization
0.64	GO:0030199	collagen fibril organization
0.63	GO:0071230	cellular response to amino acid stimulus
0.62	GO:0007266	Rho protein signal transduction
0.62	GO:0007179	transforming growth factor beta receptor signaling pathway
0.61	GO:0008217	regulation of blood pressure
0.60	GO:0001501	skeletal system development
0.60	GO:0001568	blood vessel development
0.38	GO:0030574	collagen catabolic process

0.79	GO:0005201	extracellular matrix structural constituent
0.67	GO:0048407	platelet-derived growth factor binding
0.63	GO:0046332	SMAD binding
0.62	GO:0002020	protease binding
0.60	GO:0030674	protein binding, bridging
0.56	GO:0042802	identical protein binding
0.37	GO:0042289	MHC class II protein binding
0.36	GO:0046872	metal ion binding

0.74	GO:0005581	collagen trimer
0.67	GO:0098643	banded collagen fibril
0.58	GO:0005615	extracellular space
0.55	GO:0005783	endoplasmic reticulum
0.38	GO:1903561	extracellular vesicle
0.36	GO:0005604	basement membrane
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P02523|CRBB1_RAT
Beta-crystallin B1
Search

CRYBB1

0.71	Acyl-CoA dehydrogenase, C-2 to C-3 short chain

0.76	GO:0007601	visual perception
0.36	GO:0006478	peptidyl-tyrosine sulfation
0.35	GO:0043010	camera-type eye development
0.32	GO:0055114	oxidation-reduction process

0.83	GO:0005212	structural constituent of eye lens
0.36	GO:0008476	protein-tyrosine sulfotransferase activity
0.35	GO:0005515	protein binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.30

GO:0031224

intrinsic component of membrane

0.36

EC:2.8.2.20

GO:0008476

sp|P02524|CRBB3_RAT
Beta-crystallin B3
Search

CRYBB3

0.97	Beta-crystallin B3

0.73	GO:0007601	visual perception
0.39	GO:0043010	camera-type eye development
0.34	GO:0006478	peptidyl-tyrosine sulfation
0.34	GO:0006468	protein phosphorylation
0.33	GO:0007165	signal transduction

0.80	GO:0005212	structural constituent of eye lens
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0047696	beta-adrenergic receptor kinase activity
0.35	GO:0004703	G-protein coupled receptor kinase activity
0.34	GO:0008476	protein-tyrosine sulfotransferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.37

EC:2.7.11.15

GO:0047696

sp|P02528|CRGE_RAT
Gamma-crystallin E
Search

0.96	Gamma-crystallin E

0.77	GO:0002088	lens development in camera-type eye
0.62	GO:0030855	epithelial cell differentiation
0.61	GO:0007601	visual perception
0.58	GO:0048593	camera-type eye morphogenesis
0.55	GO:0000904	cell morphogenesis involved in differentiation
0.51	GO:0034614	cellular response to reactive oxygen species
0.42	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0005515	protein binding
0.35	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P02529|CRGC_RAT
Gamma-crystallin C
Search

0.97	Gamma-crystallin C

0.73	GO:0002088	lens development in camera-type eye
0.63	GO:0007601	visual perception
0.58	GO:0030855	epithelial cell differentiation
0.56	GO:0048593	camera-type eye morphogenesis
0.54	GO:0000904	cell morphogenesis involved in differentiation
0.44	GO:0034614	cellular response to reactive oxygen species
0.38	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.77	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0005515	protein binding
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P02563|MYH6_RAT
Myosin-6
Search

MYH7

0.89	Cardiac myosin heavy chain-alpha

0.74	GO:0007018	microtubule-based movement
0.56	GO:0030049	muscle filament sliding
0.55	GO:0007512	adult heart development
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0014887	cardiac muscle adaptation
0.54	GO:0003300	cardiac muscle hypertrophy
0.54	GO:0002026	regulation of the force of heart contraction
0.54	GO:0048738	cardiac muscle tissue development
0.54	GO:0006941	striated muscle contraction
0.53	GO:0060415	muscle tissue morphogenesis

0.76	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030898	actin-dependent ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.44	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.53	GO:0030016	myofibril
0.53	GO:0097517	contractile actin filament bundle
0.53	GO:0044449	contractile fiber part
0.53	GO:0042641	actomyosin
0.34	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.33

GO:0004190

sp|P02564|MYH7_RAT
Myosin-7
Search

MYH7

0.90	Cardiac myosin heavy chain-alpha

0.74	GO:0007018	microtubule-based movement
0.56	GO:0030049	muscle filament sliding
0.55	GO:0007512	adult heart development
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0014887	cardiac muscle adaptation
0.54	GO:0003300	cardiac muscle hypertrophy
0.54	GO:0002026	regulation of the force of heart contraction
0.54	GO:0055008	cardiac muscle tissue morphogenesis
0.53	GO:0003229	ventricular cardiac muscle tissue development
0.53	GO:0060048	cardiac muscle contraction

0.75	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030898	actin-dependent ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.44	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.53	GO:0030016	myofibril
0.53	GO:0044449	contractile fiber part
0.53	GO:0097517	contractile actin filament bundle
0.53	GO:0042641	actomyosin
0.33	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.33

GO:0004190

sp|P02600|MYL1_RAT
Myosin light chain 1/3, skeletal muscle isoform
Search

MYL1

0.89	Myosin essential light chain fast

0.55	GO:0006936	muscle contraction
0.43	GO:0060047	heart contraction
0.40	GO:0002026	regulation of the force of heart contraction
0.39	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.39	GO:0006942	regulation of striated muscle contraction
0.37	GO:0033275	actin-myosin filament sliding
0.36	GO:0007519	skeletal muscle tissue development
0.36	GO:0043520	regulation of myosin II filament assembly
0.34	GO:0032781	positive regulation of ATPase activity
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.39	GO:0003785	actin monomer binding
0.37	GO:0008307	structural constituent of muscle
0.35	GO:0032038	myosin II heavy chain binding
0.35	GO:0003774	motor activity
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.55	GO:0030016	myofibril
0.42	GO:0016459	myosin complex
0.39	GO:0044449	contractile fiber part
0.35	GO:0005829	cytosol

0.34

EC:1.3.99.3

GO:0003995

sp|P02625|PRVA_RAT
Parvalbumin alpha
Search

PVALB

0.85	Parvalbumin alpha

0.39

GO:0051480

regulation of cytosolic calcium ion concentration

0.70	GO:0005509	calcium ion binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0030424	axon
0.43	GO:0043679	axon terminus
0.42	GO:0036477	somatodendritic compartment
0.38	GO:0044297	cell body
0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.35	GO:0043234	protein complex

sp|P02631|ONCO_RAT
Oncomodulin
Search

0.90	Parvalbumin alpha

0.39	GO:1905591	regulation of optical nerve axon regeneration
0.39	GO:1902336	positive regulation of retinal ganglion cell axon guidance
0.38	GO:0048687	positive regulation of sprouting of injured axon
0.38	GO:0048690	regulation of axon extension involved in regeneration
0.38	GO:0070207	protein homotrimerization
0.38	GO:0045773	positive regulation of axon extension
0.37	GO:0051289	protein homotetramerization
0.37	GO:0051480	regulation of cytosolic calcium ion concentration
0.37	GO:0009611	response to wounding
0.34	GO:0010941	regulation of cell death

0.70	GO:0005509	calcium ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.40	GO:0030424	axon
0.36	GO:0005615	extracellular space
0.36	GO:0099512	supramolecular fiber
0.36	GO:0031982	vesicle
0.35	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.34	GO:0043234	protein complex

sp|P02634|S100G_RAT
Protein S100-G
Search

sp|P02650|APOE_RAT
Apolipoprotein E
Search

APOE

0.97	Apolipoprotein E

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.70	GO:1903000	regulation of lipid transport across blood brain barrier
0.70	GO:1905860	positive regulation of heparan sulfate proteoglycan binding
0.70	GO:1905890	regulation of cellular response to very-low-density lipoprotein particle stimulus
0.70	GO:1901630	negative regulation of presynaptic membrane organization
0.70	GO:1905853	regulation of heparan sulfate binding
0.70	GO:1902995	positive regulation of phospholipid efflux
0.70	GO:0034372	very-low-density lipoprotein particle remodeling
0.70	GO:0010873	positive regulation of cholesterol esterification

0.73	GO:0008201	heparin binding
0.72	GO:0008289	lipid binding
0.71	GO:0070326	very-low-density lipoprotein particle receptor binding
0.71	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.70	GO:0046911	metal chelating activity
0.69	GO:0001540	amyloid-beta binding
0.68	GO:0048156	tau protein binding
0.68	GO:0050750	low-density lipoprotein particle receptor binding
0.67	GO:0017127	cholesterol transporter activity
0.66	GO:0071813	lipoprotein particle binding

0.77	GO:0042627	chylomicron
0.77	GO:0034385	triglyceride-rich plasma lipoprotein particle
0.77	GO:0034364	high-density lipoprotein particle
0.68	GO:0034362	low-density lipoprotein particle
0.67	GO:0106003	amyloid-beta complex
0.57	GO:0031012	extracellular matrix
0.55	GO:0005794	Golgi apparatus
0.55	GO:0005783	endoplasmic reticulum
0.48	GO:0072562	blood microparticle
0.46	GO:0005886	plasma membrane

sp|P02651|APOA4_RAT
Apolipoprotein A-IV
Search

APOA4

0.97	Apolipoprotein A-IV

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.71	GO:0034444	regulation of plasma lipoprotein oxidation
0.71	GO:0034372	very-low-density lipoprotein particle remodeling
0.70	GO:0051006	positive regulation of lipoprotein lipase activity
0.70	GO:0010873	positive regulation of cholesterol esterification
0.70	GO:0006982	response to lipid hydroperoxide
0.70	GO:0044240	multicellular organismal lipid catabolic process
0.69	GO:0045723	positive regulation of fatty acid biosynthetic process
0.69	GO:0010898	positive regulation of triglyceride catabolic process

0.72	GO:0008289	lipid binding
0.71	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.69	GO:0050997	quaternary ammonium group binding
0.68	GO:0017127	cholesterol transporter activity
0.65	GO:0070405	ammonium ion binding
0.58	GO:0042803	protein homodimerization activity
0.56	GO:0005507	copper ion binding
0.55	GO:0016209	antioxidant activity
0.51	GO:0043178	alcohol binding
0.45	GO:0043168	anion binding

0.70	GO:0042627	chylomicron
0.69	GO:0034364	high-density lipoprotein particle
0.66	GO:0034361	very-low-density lipoprotein particle
0.59	GO:0009986	cell surface
0.58	GO:0031012	extracellular matrix
0.52	GO:0072562	blood microparticle
0.41	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol
0.37	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005769	early endosome

sp|P02661|CASA1_RAT
Alpha-S1-casein
Search

CSN1S1

0.83	Alpha-S1-casein

0.39

GO:0043984

histone H4-K16 acetylation

0.66	GO:0005576	extracellular region
0.38	GO:0072487	MSL complex
0.30	GO:0031224	intrinsic component of membrane

sp|P02665|CASB_RAT
Beta-casein
Search

CSN2

0.93	Beta-casein

0.62	GO:0007595	lactation
0.60	GO:2000117	negative regulation of cysteine-type endopeptidase activity
0.58	GO:1903488	negative regulation of lactation
0.49	GO:0006816	calcium ion transport
0.39	GO:1903720	negative regulation of I-kappaB phosphorylation
0.39	GO:1903494	response to dehydroepiandrosterone
0.39	GO:1903496	response to 11-deoxycorticosterone
0.38	GO:0009408	response to heat
0.38	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.38	GO:0032570	response to progesterone

0.59	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.47	GO:0005509	calcium ion binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0019870	potassium channel inhibitor activity
0.37	GO:0008191	metalloendopeptidase inhibitor activity
0.35	GO:0016209	antioxidant activity

0.66	GO:0005576	extracellular region
0.38	GO:0005796	Golgi lumen

sp|P02667|CS2LA_RAT
Alpha-S2-casein-like A
Search

0.11	Alpha s2 casein

0.38	GO:1903494	response to dehydroepiandrosterone
0.38	GO:1903496	response to 11-deoxycorticosterone
0.38	GO:0032570	response to progesterone
0.37	GO:0060416	response to growth hormone
0.37	GO:0032355	response to estradiol
0.36	GO:0042742	defense response to bacterium

0.62	GO:0035375	zymogen binding
0.52	GO:0042803	protein homodimerization activity

0.66	GO:0005576	extracellular region
0.38	GO:0005796	Golgi lumen

sp|P02680|FIBG_RAT
Fibrinogen gamma chain
Search

FGG

0.97	Fibrinogen gamma polypeptide

0.82	GO:0007596	blood coagulation
0.76	GO:0001775	cell activation
0.74	GO:0051258	protein polymerization
0.61	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.61	GO:0042730	fibrinolysis
0.61	GO:0072376	protein activation cascade
0.60	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.60	GO:0045907	positive regulation of vasoconstriction
0.60	GO:2000352	negative regulation of endothelial cell apoptotic process
0.60	GO:0031639	plasminogen activation

0.77	GO:0030674	protein binding, bridging
0.70	GO:0005102	receptor binding
0.56	GO:0050839	cell adhesion molecule binding
0.46	GO:0005198	structural molecule activity
0.38	GO:0042803	protein homodimerization activity
0.36	GO:0046872	metal ion binding

0.84	GO:0005577	fibrinogen complex
0.60	GO:0031091	platelet alpha granule
0.57	GO:0009897	external side of plasma membrane
0.40	GO:0072562	blood microparticle
0.38	GO:0070062	extracellular exosome
0.37	GO:0005938	cell cortex
0.36	GO:0034774	secretory granule lumen
0.36	GO:0005788	endoplasmic reticulum lumen

sp|P02683|NSG1_RAT
Neuron-specific protein family member 1
Search

HGNC:18790

0.97	Neuronal vesicle trafficking-associated protein 1

0.85	GO:0007212	dopamine receptor signaling pathway
0.83	GO:0048268	clathrin coat assembly
0.58	GO:0099627	neurotransmitter receptor cycle
0.57	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane
0.55	GO:0042982	amyloid precursor protein metabolic process
0.55	GO:0001881	receptor recycling
0.50	GO:0006915	apoptotic process
0.43	GO:0098814	spontaneous synaptic transmission
0.42	GO:1900271	regulation of long-term synaptic potentiation
0.40	GO:0001921	positive regulation of receptor recycling

0.85	GO:0032051	clathrin light chain binding
0.37	GO:0005102	receptor binding
0.34	GO:0003677	DNA binding
0.33	GO:0003730	mRNA 3'-UTR binding
0.33	GO:0045182	translation regulator activity

0.54	GO:0005770	late endosome
0.53	GO:0016328	lateral plasma membrane
0.51	GO:0045211	postsynaptic membrane
0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005794	Golgi apparatus
0.45	GO:0043202	lysosomal lumen
0.44	GO:0010008	endosome membrane
0.43	GO:0030659	cytoplasmic vesicle membrane
0.43	GO:0030425	dendrite
0.42	GO:0005769	early endosome

sp|P02688|MBP_RAT
Myelin basic protein
Search

MBP

0.73	Myelin basic protein transcript variant 1

0.55	GO:0042552	myelination
0.51	GO:0007605	sensory perception of sound
0.45	GO:0009636	response to toxic substance
0.45	GO:0061024	membrane organization
0.44	GO:0007417	central nervous system development
0.42	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion
0.42	GO:0035633	maintenance of permeability of blood-brain barrier
0.42	GO:1904685	positive regulation of metalloendopeptidase activity
0.41	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.41	GO:0034115	negative regulation of heterotypic cell-cell adhesion

0.86	GO:0019911	structural constituent of myelin sheath
0.52	GO:0002020	protease binding
0.51	GO:0005516	calmodulin binding
0.34	GO:0005543	phospholipid binding

0.59	GO:0033269	internode region of axon
0.55	GO:0043209	myelin sheath
0.53	GO:0043025	neuronal cell body
0.43	GO:0043234	protein complex
0.42	GO:0071944	cell periphery
0.33	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P02692|FABPL_RAT
Fatty acid-binding protein, liver
Search

FABP1

0.85	Fatty acid-binding protein, liver

0.57	GO:0070301	cellular response to hydrogen peroxide
0.57	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:0071456	cellular response to hypoxia
0.49	GO:0098869	cellular oxidant detoxification
0.43	GO:0032000	positive regulation of fatty acid beta-oxidation
0.42	GO:0050892	intestinal absorption
0.40	GO:0015909	long-chain fatty acid transport
0.39	GO:0051345	positive regulation of hydrolase activity
0.36	GO:0051977	lysophospholipid transport
0.36	GO:0019082	viral protein processing

0.74	GO:0005504	fatty acid binding
0.69	GO:0032052	bile acid binding
0.52	GO:0003682	chromatin binding
0.49	GO:0016209	antioxidant activity
0.42	GO:0005324	long-chain fatty acid transporter activity
0.39	GO:0005543	phospholipid binding
0.36	GO:0051978	lysophospholipid transporter activity
0.35	GO:0008144	drug binding
0.35	GO:0005515	protein binding

0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.42	GO:0045179	apical cortex
0.41	GO:0031907	microbody lumen
0.40	GO:0044439	peroxisomal part
0.37	GO:0070062	extracellular exosome
0.36	GO:0043234	protein complex

sp|P02693|FABPI_RAT
Fatty acid-binding protein, intestinal
Search

FABP2

0.97	Intestinal fatty acid binding protein 2

0.37	GO:0007586	digestion
0.35	GO:0019433	triglyceride catabolic process
0.35	GO:0015909	long-chain fatty acid transport
0.34	GO:0003008	system process
0.34	GO:0006631	fatty acid metabolic process

0.85	GO:0005504	fatty acid binding
0.35	GO:0005324	long-chain fatty acid transporter activity
0.33	GO:0005515	protein binding

0.38	GO:0031526	brush border membrane
0.38	GO:0005622	intracellular
0.35	GO:0005902	microvillus
0.35	GO:0045177	apical part of cell
0.34	GO:0043227	membrane-bounded organelle

sp|P02696|RET1_RAT
Retinol-binding protein 1
Search

RBP1

0.97	Nicotinamide nucleotide adenylyltransferase 3

0.85	GO:0006776	vitamin A metabolic process
0.84	GO:0002138	retinoic acid biosynthetic process
0.55	GO:0033189	response to vitamin A
0.54	GO:0030852	regulation of granulocyte differentiation
0.53	GO:0042572	retinol metabolic process
0.39	GO:0055088	lipid homeostasis
0.35	GO:0009435	NAD biosynthetic process
0.34	GO:0009611	response to wounding

0.72	GO:0008289	lipid binding
0.43	GO:0019842	vitamin binding
0.41	GO:0043178	alcohol binding
0.38	GO:0016779	nucleotidyltransferase activity
0.32	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0005829	cytosol
0.51	GO:0005811	lipid droplet
0.47	GO:0005654	nucleoplasm
0.38	GO:0044297	cell body
0.34	GO:0070062	extracellular exosome
0.32	GO:0005739	mitochondrion

0.38

GO:0016779

sp|P02706|ASGR1_RAT
Asialoglycoprotein receptor 1
Search

0.96	Asialoglycoprotein receptor 1

0.49	GO:0031668	cellular response to extracellular stimulus
0.47	GO:0055088	lipid homeostasis
0.46	GO:0031647	regulation of protein stability
0.45	GO:0009100	glycoprotein metabolic process
0.41	GO:0006897	endocytosis
0.38	GO:0030282	bone mineralization
0.37	GO:0018196	peptidyl-asparagine modification
0.36	GO:0043413	macromolecule glycosylation
0.34	GO:1901137	carbohydrate derivative biosynthetic process
0.34	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.51	GO:0042803	protein homodimerization activity
0.45	GO:0004873	asialoglycoprotein receptor activity
0.35	GO:0046872	metal ion binding

0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005576	extracellular region

sp|P02761|MUP_RAT
Major urinary protein
Search

0.73	Salivary lipocalin

0.50	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.49	GO:0031649	heat generation
0.49	GO:0010888	negative regulation of lipid storage
0.48	GO:0070584	mitochondrion morphogenesis
0.48	GO:0045475	locomotor rhythm
0.48	GO:0010907	positive regulation of glucose metabolic process
0.48	GO:0008286	insulin receptor signaling pathway
0.47	GO:0045721	negative regulation of gluconeogenesis
0.47	GO:0051897	positive regulation of protein kinase B signaling
0.47	GO:0045834	positive regulation of lipid metabolic process

0.51	GO:0005550	pheromone binding
0.51	GO:0036094	small molecule binding
0.50	GO:0005009	insulin-activated receptor activity
0.38	GO:0004866	endopeptidase inhibitor activity
0.38	GO:0005186	pheromone activity

0.45	GO:0005615	extracellular space
0.42	GO:0005829	cytosol
0.40	GO:0005634	nucleus

sp|P02764|A1AG_RAT
Alpha-1-acid glycoprotein
Search

0.97	Alpha-1-acid glycoprotein 1

0.71	GO:0002682	regulation of immune system process
0.61	GO:0006953	acute-phase response
0.53	GO:1904469	positive regulation of tumor necrosis factor secretion
0.53	GO:0050718	positive regulation of interleukin-1 beta secretion
0.50	GO:0032715	negative regulation of interleukin-6 production
0.50	GO:0032720	negative regulation of tumor necrosis factor production
0.45	GO:0002439	chronic inflammatory response to antigenic stimulus
0.45	GO:0033197	response to vitamin E
0.44	GO:0002438	acute inflammatory response to antigenic stimulus
0.43	GO:0031100	animal organ regeneration

0.36	GO:0008144	drug binding
0.35	GO:0005515	protein binding

0.73	GO:0005615	extracellular space
0.47	GO:0031012	extracellular matrix
0.46	GO:1903561	extracellular vesicle
0.44	GO:0035580	specific granule lumen
0.44	GO:0031093	platelet alpha granule lumen
0.40	GO:1904724	tertiary granule lumen
0.40	GO:0035578	azurophil granule lumen

sp|P02767|TTHY_RAT
Transthyretin
Search

TTR

0.95	Transthyretin

0.85	GO:0070327	thyroid hormone transport
0.85	GO:0042572	retinol metabolic process
0.47	GO:0010469	regulation of receptor activity
0.45	GO:0006144	purine nucleobase metabolic process
0.38	GO:0051262	protein tetramerization
0.37	GO:0051260	protein homooligomerization
0.35	GO:0042403	thyroid hormone metabolic process
0.35	GO:0001555	oocyte growth
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0030198	extracellular matrix organization

0.86	GO:0070324	thyroid hormone binding
0.48	GO:0042802	identical protein binding
0.48	GO:0005179	hormone activity
0.39	GO:0046982	protein heterodimerization activity
0.37	GO:0033971	hydroxyisourate hydrolase activity
0.34	GO:0019904	protein domain specific binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0036094	small molecule binding

0.66	GO:0005576	extracellular region
0.36	GO:0043234	protein complex
0.36	GO:0031982	vesicle
0.35	GO:0060417	yolk
0.35	GO:0005766	primary lysosome
0.35	GO:0005775	vacuolar lumen
0.33	GO:0012505	endomembrane system
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:3.5.2.17	GO:0033971
0.37	KEGG:R06601	GO:0033971

sp|P02770|ALBU_RAT
Serum albumin
Search

ALB

0.94	serum albumin precursor

0.61	GO:0051659	maintenance of mitochondrion location
0.58	GO:0019836	hemolysis by symbiont of host erythrocytes
0.53	GO:0009267	cellular response to starvation
0.53	GO:0043066	negative regulation of apoptotic process
0.37	GO:0001895	retina homeostasis
0.37	GO:0070541	response to platinum ion
0.37	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
0.36	GO:0007584	response to nutrient
0.36	GO:0042311	vasodilation
0.35	GO:0002576	platelet degranulation

0.57	GO:0005504	fatty acid binding
0.56	GO:0015643	toxic substance binding
0.54	GO:0019825	oxygen binding
0.49	GO:0051087	chaperone binding
0.48	GO:0042802	identical protein binding
0.48	GO:0030170	pyridoxal phosphate binding
0.42	GO:0003677	DNA binding
0.39	GO:0046872	metal ion binding
0.35	GO:0004817	cysteine-tRNA ligase activity
0.34	GO:0019899	enzyme binding

0.73	GO:0005615	extracellular space
0.51	GO:0043209	myelin sheath
0.51	GO:1903561	extracellular vesicle
0.48	GO:0005794	Golgi apparatus
0.47	GO:0005783	endoplasmic reticulum
0.44	GO:0043234	protein complex
0.36	GO:0031093	platelet alpha granule lumen
0.35	GO:0005604	basement membrane
0.35	GO:0060417	yolk
0.34	GO:0005634	nucleus

0.35

EC:6.1.1.16

GO:0004817

sp|P02773|FETA_RAT
Alpha-fetoprotein
Search

0.80	Alpha-fetoprotein (Fragment)

0.63	GO:0001542	ovulation from ovarian follicle
0.63	GO:0042448	progesterone metabolic process
0.60	GO:0060395	SMAD protein signal transduction
0.43	GO:0071693	protein transport within extracellular region
0.40	GO:0050821	protein stabilization
0.39	GO:0051180	vitamin transport
0.38	GO:0031100	animal organ regeneration
0.37	GO:0031016	pancreas development
0.37	GO:0001889	liver development
0.37	GO:0051659	maintenance of mitochondrion location

0.43	GO:0008431	vitamin E binding
0.38	GO:0046872	metal ion binding
0.36	GO:0005504	fatty acid binding
0.36	GO:0015643	toxic substance binding
0.36	GO:0005515	protein binding
0.35	GO:0019825	oxygen binding
0.34	GO:0030170	pyridoxal phosphate binding
0.33	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.40	GO:0005737	cytoplasm
0.37	GO:1903561	extracellular vesicle
0.36	GO:0043209	myelin sheath
0.36	GO:0012505	endomembrane system
0.34	GO:0043233	organelle lumen
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part

sp|P02780|SG2A2_RAT
Secretoglobin family 2A member 2
Search

SCGB2A2

0.94	Mammaglobin-A

0.66	GO:0030521	androgen receptor signaling pathway
0.62	GO:0051262	protein tetramerization

0.75	GO:0005496	steroid binding
0.58	GO:0046982	protein heterodimerization activity

0.62

GO:0005576

extracellular region

sp|P02781|PSC2_RAT
Prostatic steroid-binding protein C2
Search

0.84	Secretoglobin family 1D member 2

0.56

GO:0007165

signal transduction

0.52

GO:0005615

extracellular space

sp|P02782|PSC1_RAT
Prostatic steroid-binding protein C1
Search

0.90	Prostatic steroid-binding protein C1

0.82

GO:0005496

steroid binding

0.73

GO:0005615

extracellular space

sp|P02783|SVS4_RAT
Seminal vesicle secretory protein 4
Search

SVS4

0.93	Seminal vesicle secretory protein 4

0.77

GO:0070207

protein homotrimerization

0.75	GO:0043621	protein self-association
0.66	GO:0042802	identical protein binding

0.73	GO:0005615	extracellular space
0.54	GO:0043234	protein complex

sp|P02793|FRIL1_RAT
Ferritin light chain 1
Search

FTL

0.55	Ferritin light chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.57	GO:0051238	sequestering of metal ion
0.53	GO:0051651	maintenance of location in cell
0.36	GO:0010288	response to lead ion
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0055114	oxidation-reduction process

0.75	GO:0008199	ferric iron binding
0.38	GO:0042802	identical protein binding
0.36	GO:0004322	ferroxidase activity
0.32	GO:0016874	ligase activity

0.49	GO:0070288	ferritin complex
0.41	GO:0044754	autolysosome
0.37	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0005766	primary lysosome
0.35	GO:0005775	vacuolar lumen
0.35	GO:0030139	endocytic vesicle
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.16.3.1

GO:0004322

sp|P02803|MT1_RAT
Metallothionein-1
Search

0.75	Metallothionein-II, hippocampal

0.63	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.46	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.43	GO:0010273	detoxification of copper ion
0.42	GO:0007263	nitric oxide mediated signal transduction
0.41	GO:0006882	cellular zinc ion homeostasis
0.41	GO:0035690	cellular response to drug
0.41	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.35	GO:0008144	drug binding
0.35	GO:0005515	protein binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.38	GO:0005764	lysosome
0.37	GO:0005829	cytosol

sp|P03889|NU1M_RAT
NADH-ubiquinone oxidoreductase chain 1
Search

ND1

0.44	NADH-ubiquinone oxidoreductase chain 1

0.52	GO:0055114	oxidation-reduction process
0.38	GO:0033194	response to hydroperoxide
0.36	GO:0014070	response to organic cyclic compound
0.36	GO:0042493	response to drug
0.34	GO:0006091	generation of precursor metabolites and energy

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.41	GO:0045271	respiratory chain complex I
0.40	GO:0098798	mitochondrial protein complex
0.39	GO:1990204	oxidoreductase complex
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P03926|NU6M_RAT
NADH-ubiquinone oxidoreductase chain 6
Search

ND6

0.49	NADH-ubiquinone oxidoreductase chain 6

0.53	GO:0055114	oxidation-reduction process
0.38	GO:0042220	response to cocaine
0.38	GO:0035094	response to nicotine
0.38	GO:0042542	response to hydrogen peroxide

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.36	GO:0070469	respiratory chain
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P03957|MMP3_RAT
Stromelysin-1
Search

0.70	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.57	GO:0030574	collagen catabolic process
0.57	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.54	GO:0032461	positive regulation of protein oligomerization
0.48	GO:0030334	regulation of cell migration
0.47	GO:0022617	extracellular matrix disassembly
0.45	GO:0003417	growth plate cartilage development
0.45	GO:0001958	endochondral ossification
0.44	GO:0030282	bone mineralization
0.42	GO:0042060	wound healing

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.47	GO:0005518	collagen binding
0.43	GO:0005509	calcium ion binding
0.40	GO:0001047	core promoter binding
0.38	GO:0004252	serine-type endopeptidase activity
0.37	GO:0043565	sequence-specific DNA binding
0.34	GO:0001968	fibronectin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.42	GO:0005615	extracellular space
0.39	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.37	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0030425	dendrite
0.35	GO:0044297	cell body
0.35	GO:0005581	collagen trimer
0.35	GO:0005739	mitochondrion
0.35	GO:0046581	intercellular canaliculus

0.70

GO:0004222

sp|P03994|HPLN1_RAT
Hyaluronan and proteoglycan link protein 1
Search

HAPLN1

0.97	Hyaluronan and proteoglycan link protein 1

0.71	GO:0007155	cell adhesion
0.48	GO:0001501	skeletal system development
0.47	GO:0007417	central nervous system development
0.40	GO:0031101	fin regeneration
0.35	GO:0030198	extracellular matrix organization
0.35	GO:0002040	sprouting angiogenesis

0.83	GO:0005540	hyaluronic acid binding
0.49	GO:0005201	extracellular matrix structural constituent

0.53	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|P04041|GPX1_RAT
Glutathione peroxidase 1
Search

GPX1

0.47	Glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.54	GO:0009609	response to symbiotic bacterium
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
0.52	GO:0051450	myoblast proliferation
0.52	GO:0010269	response to selenium ion
0.51	GO:0001659	temperature homeostasis
0.51	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.51	GO:0043403	skeletal muscle tissue regeneration

0.79	GO:0004602	glutathione peroxidase activity
0.47	GO:0017124	SH3 domain binding
0.37	GO:0003924	GTPase activity
0.36	GO:0005525	GTP binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0031685	adenosine receptor binding
0.33	GO:0009055	electron transfer activity
0.32	GO:0042802	identical protein binding

0.51	GO:0097413	Lewy body
0.45	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.39	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.31	GO:0005886	plasma membrane

0.79

EC:1.11.1.9

GO:0004602

sp|P04055|PA21B_RAT
Phospholipase A2
Search

PLA2G1B

0.67	Phospholipase A2, major isoenzyme

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.54	GO:0002227	innate immune response in mucosa
0.54	GO:0044241	lipid digestion
0.53	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.53	GO:0044243	multicellular organismal catabolic process
0.53	GO:0019731	antibacterial humoral response
0.53	GO:0045740	positive regulation of DNA replication
0.52	GO:0050830	defense response to Gram-positive bacterium

0.82	GO:0004623	phospholipase A2 activity
0.79	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.79	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.70	GO:0005509	calcium ion binding
0.47	GO:0005102	receptor binding
0.42	GO:0090729	toxin activity
0.37	GO:0032052	bile acid binding
0.33	GO:0003723	RNA binding
0.32	GO:0016301	kinase activity

0.65	GO:0005576	extracellular region
0.49	GO:0009986	cell surface
0.46	GO:0005829	cytosol
0.38	GO:0030141	secretory granule
0.37	GO:0072556	other organism presynaptic membrane
0.30	GO:0016020	membrane

0.82

EC:3.1.1.4

GO:0004623

sp|P04073|PEPC_RAT
Gastricsin
Search

PGC

0.93	Progastricsin

0.61	GO:0006508	proteolysis
0.56	GO:0002803	positive regulation of antibacterial peptide production
0.48	GO:0006914	autophagy
0.46	GO:0007586	digestion
0.45	GO:0030163	protein catabolic process
0.39	GO:0051604	protein maturation
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.33	GO:0042803	protein homodimerization activity

0.49	GO:0005615	extracellular space
0.37	GO:0031982	vesicle
0.37	GO:0043230	extracellular organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0044444	cytoplasmic part
0.33	GO:0043229	intracellular organelle
0.30	GO:0016020	membrane

sp|P04089|PTHY_RAT
Parathyroid hormone
Search

PTH

0.97	Parathyroid hormone

0.81	GO:0046326	positive regulation of glucose import
0.80	GO:0006874	cellular calcium ion homeostasis
0.76	GO:0010469	regulation of receptor activity
0.69	GO:0090290	positive regulation of osteoclast proliferation
0.69	GO:0071865	regulation of apoptotic process in bone marrow
0.69	GO:0060732	positive regulation of inositol phosphate biosynthetic process
0.68	GO:0045725	positive regulation of glycogen biosynthetic process
0.68	GO:0071864	positive regulation of cell proliferation in bone marrow
0.68	GO:0007202	activation of phospholipase C activity
0.67	GO:0030819	positive regulation of cAMP biosynthetic process

0.79	GO:0005179	hormone activity
0.72	GO:0031856	parathyroid hormone receptor binding
0.68	GO:0051428	peptide hormone receptor binding
0.65	GO:0047485	protein N-terminus binding
0.64	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.66	GO:0005576	extracellular region
0.39	GO:0005622	intracellular

sp|P04094|PENK_RAT
Proenkephalin-A
Search

PENK

0.95	Proenkephalin-A-A

0.80	GO:0007218	neuropeptide signaling pathway
0.61	GO:0010469	regulation of receptor activity
0.60	GO:0002118	aggressive behavior
0.59	GO:0001964	startle response
0.59	GO:0001662	behavioral fear response
0.58	GO:0019233	sensory perception of pain
0.56	GO:0007626	locomotory behavior
0.46	GO:0007268	chemical synaptic transmission
0.43	GO:0051867	general adaptation syndrome, behavioral process
0.43	GO:2000987	positive regulation of behavioral fear response

0.71	GO:0001515	opioid peptide activity
0.52	GO:0031628	opioid receptor binding
0.49	GO:0005184	neuropeptide hormone activity
0.33	GO:0016849	phosphorus-oxygen lyase activity

0.54	GO:0005576	extracellular region
0.49	GO:0043679	axon terminus
0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.43	GO:0032280	symmetric synapse
0.42	GO:0070852	cell body fiber
0.40	GO:0030424	axon
0.39	GO:0005886	plasma membrane
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:4.6

GO:0016849

sp|P04143|THRSP_RAT
Thyroid hormone-inducible hepatic protein
Search

THRSP

0.97	Thyroid hormone responsive

0.86	GO:0010866	regulation of triglyceride biosynthetic process
0.44	GO:0006853	carnitine shuttle
0.43	GO:0006629	lipid metabolic process
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.75

GO:0042803

protein homodimerization activity

0.69	GO:0005654	nucleoplasm
0.69	GO:0005829	cytosol

sp|P04157|PTPRC_RAT
Receptor-type tyrosine-protein phosphatase C
Search

PTPRC

0.44	Receptor-type tyrosine-protein phosphatase C

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.67	GO:0050852	T cell receptor signaling pathway
0.45	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.44	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway
0.44	GO:0042100	B cell proliferation
0.44	GO:0050853	B cell receptor signaling pathway
0.43	GO:0042102	positive regulation of T cell proliferation
0.43	GO:0051209	release of sequestered calcium ion into cytosol
0.43	GO:0030217	T cell differentiation
0.42	GO:0006469	negative regulation of protein kinase activity

0.75	GO:0004725	protein tyrosine phosphatase activity
0.42	GO:0019901	protein kinase binding
0.39	GO:0043395	heparan sulfate proteoglycan binding
0.39	GO:0008201	heparin binding
0.38	GO:0019198	transmembrane receptor protein phosphatase activity
0.36	GO:0019887	protein kinase regulator activity

0.42	GO:0005925	focal adhesion
0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0009897	external side of plasma membrane
0.38	GO:0098857	membrane microdomain
0.36	GO:0070062	extracellular exosome
0.36	GO:0009898	cytoplasmic side of plasma membrane
0.31	GO:0030667	secretory granule membrane

0.75

GO:0004725

sp|P04166|CYB5B_RAT
Cytochrome b5 type B
Search

CYB5B

0.62	Outer mitochondrial membrane cytochrome b5 isoform B

0.37	GO:0043085	positive regulation of catalytic activity
0.36	GO:0006366	transcription by RNA polymerase II
0.35	GO:0071466	cellular response to xenobiotic stimulus
0.35	GO:0055114	oxidation-reduction process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.33	GO:0006091	generation of precursor metabolites and energy

0.61	GO:0020037	heme binding
0.52	GO:0046872	metal ion binding
0.37	GO:0008047	enzyme activator activity
0.37	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0045153	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.43	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.40	GO:0031968	organelle outer membrane
0.30	GO:0016021	integral component of membrane

sp|P04167|CP2B2_RAT
Cytochrome P450 2B2
Search

CYP2B

0.97	Testosterone 16a-hydroxylase type b

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0019373	epoxygenase P450 pathway
0.47	GO:0042738	exogenous drug catabolic process
0.44	GO:0006805	xenobiotic metabolic process
0.43	GO:0008202	steroid metabolic process
0.41	GO:0042180	cellular ketone metabolic process
0.38	GO:0014070	response to organic cyclic compound
0.37	GO:0051592	response to calcium ion
0.36	GO:0018933	nicotine metabolic process
0.36	GO:0010477	response to sulfur dioxide

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.51	GO:0008392	arachidonic acid epoxygenase activity
0.49	GO:0008395	steroid hydroxylase activity
0.37	GO:0019825	oxygen binding
0.34	GO:0004721	phosphoprotein phosphatase activity

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P04176|PH4H_RAT
Phenylalanine-4-hydroxylase
Search

PAH

0.65	Phenylalanine hydroxylase

0.77	GO:0006559	L-phenylalanine catabolic process
0.53	GO:0055114	oxidation-reduction process
0.44	GO:0071391	cellular response to estrogen stimulus
0.36	GO:0006726	eye pigment biosynthetic process
0.36	GO:0007616	long-term memory
0.35	GO:0042423	catecholamine biosynthetic process
0.35	GO:0018126	protein hydroxylation
0.35	GO:0046146	tetrahydrobiopterin metabolic process
0.34	GO:0006571	tyrosine biosynthetic process
0.34	GO:0042136	neurotransmitter biosynthetic process

0.83	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
0.63	GO:0005506	iron ion binding
0.34	GO:0016597	amino acid binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0048037	cofactor binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.83

EC:1.14.16

GO:0016714

sp|P04177|TY3H_RAT
Tyrosine 3-monooxygenase
Search

0.88	Tyrosine hydroxylase

0.79	GO:0042423	catecholamine biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.61	GO:0007617	mating behavior
0.60	GO:0042417	dopamine metabolic process
0.56	GO:0007625	grooming behavior
0.56	GO:0071625	vocalization behavior
0.56	GO:0035176	social behavior
0.56	GO:0042414	epinephrine metabolic process
0.55	GO:0060416	response to growth hormone
0.54	GO:0001963	synaptic transmission, dopaminergic

0.82	GO:0004511	tyrosine 3-monooxygenase activity
0.62	GO:0005506	iron ion binding
0.46	GO:0019899	enzyme binding
0.42	GO:0004510	tryptophan 5-monooxygenase activity
0.39	GO:0034617	tetrahydrobiopterin binding
0.38	GO:0035240	dopamine binding
0.37	GO:0019825	oxygen binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0016597	amino acid binding
0.34	GO:0005179	hormone activity

0.54	GO:0033162	melanosome membrane
0.53	GO:0043204	perikaryon
0.53	GO:0005790	smooth endoplasmic reticulum
0.50	GO:0030424	axon
0.48	GO:0009898	cytoplasmic side of plasma membrane
0.43	GO:0005634	nucleus
0.37	GO:0043679	axon terminus
0.37	GO:0008021	synaptic vesicle
0.37	GO:0030425	dendrite
0.35	GO:0070852	cell body fiber

0.82

EC:1.14.16.2

GO:0004511

sp|P04182|OAT_RAT
Ornithine aminotransferase, mitochondrial
Search

OAT

0.54	Ornithine aminotransferaseserine-threonine

0.56	GO:0034214	protein hexamerization
0.38	GO:0055129	L-proline biosynthetic process
0.34	GO:0007601	visual perception
0.34	GO:0006591	ornithine metabolic process

0.83	GO:0004587	ornithine-oxo-acid transaminase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.43	GO:0042802	identical protein binding
0.34	GO:0003992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
0.33	GO:0008453	alanine-glyoxylate transaminase activity

0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.83	EC:2.6.1.13	GO:0004587
0.34	KEGG:R02283	GO:0003992

sp|P04218|OX2G_RAT
OX-2 membrane glycoprotein
Search

CD200

0.91	OX-2 membrane glycoprotein isoform a

0.86	GO:0043031	negative regulation of macrophage activation
0.72	GO:0050776	regulation of immune response
0.52	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.49	GO:0008037	cell recognition
0.48	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.49	GO:0050839	cell adhesion molecule binding
0.47	GO:0042803	protein homodimerization activity
0.46	GO:0005102	receptor binding
0.43	GO:0004872	receptor activity

0.50	GO:0005913	cell-cell adherens junction
0.44	GO:0005887	integral component of plasma membrane

sp|P04256|ROA1_RAT
Heterogeneous nuclear ribonucleoprotein A1
Search

HNRNPA1

0.88	Heterogeneous nuclear ribonucleoprotein A1

0.53	GO:1903936	cellular response to sodium arsenite
0.48	GO:0032211	negative regulation of telomere maintenance via telomerase
0.48	GO:0032212	positive regulation of telomere maintenance via telomerase
0.47	GO:0042149	cellular response to glucose starvation
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.44	GO:0051168	nuclear export
0.44	GO:0051170	nuclear import
0.43	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.49	GO:0098505	G-rich strand telomeric DNA binding
0.45	GO:0019904	protein domain specific binding
0.38	GO:0036310	annealing helicase activity
0.38	GO:0042802	identical protein binding
0.36	GO:0008134	transcription factor binding

0.65	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0044428	nuclear part
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:1902494	catalytic complex
0.39	GO:0070062	extracellular exosome
0.38	GO:0030117	membrane coat
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P04276|VTDB_RAT
Vitamin D-binding protein
Search

0.97	vitamin D-binding protein isoform X1

0.81	GO:0035461	vitamin transmembrane transport
0.64	GO:0042359	vitamin D metabolic process
0.38	GO:0007595	lactation
0.38	GO:0032355	response to estradiol
0.38	GO:0007565	female pregnancy
0.37	GO:0048545	response to steroid hormone
0.37	GO:0031667	response to nutrient levels

0.87	GO:0005499	vitamin D binding
0.76	GO:0090482	vitamin transmembrane transporter activity
0.56	GO:0003779	actin binding
0.44	GO:0008144	drug binding

0.73	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.38	GO:0043202	lysosomal lumen
0.37	GO:0005829	cytosol
0.37	GO:0030424	axon
0.37	GO:0048471	perinuclear region of cytoplasm

sp|P04355|MT2_RAT
Metallothionein-2
Search

0.75	Metallothionein-II, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.48	GO:0071276	cellular response to cadmium ion
0.45	GO:0036015	response to interleukin-3
0.43	GO:0010273	detoxification of copper ion
0.43	GO:0007263	nitric oxide mediated signal transduction
0.42	GO:0006882	cellular zinc ion homeostasis
0.41	GO:0035690	cellular response to drug
0.40	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.36	GO:0008144	drug binding

0.54	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.37	GO:0005764	lysosome

sp|P04462|MYH8_RAT
Myosin-8 (Fragment)
Search

0.52	Skeletal muscle myosin heavy chain type IIa (Fragment)

0.72	GO:0007018	microtubule-based movement
0.56	GO:0006936	muscle contraction
0.55	GO:0070252	actin-mediated cell contraction
0.52	GO:0014823	response to activity
0.50	GO:0050881	musculoskeletal movement
0.46	GO:0001778	plasma membrane repair
0.41	GO:0046034	ATP metabolic process
0.39	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.76	GO:0051015	actin filament binding
0.73	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005516	calmodulin binding
0.42	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.49	GO:0014704	intercalated disc
0.45	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0005826	actomyosin contractile ring
0.41	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.42

GO:0016887

sp|P04466|MLRS_RAT
Myosin regulatory light chain 2, skeletal muscle isoform
Search

MYLPF

0.92	Phosphorylatable fast skeletal muscle myosin light chain

0.54	GO:0014706	striated muscle tissue development
0.54	GO:0007517	muscle organ development
0.43	GO:0098735	positive regulation of the force of heart contraction
0.42	GO:0042694	muscle cell fate specification
0.42	GO:0006936	muscle contraction
0.41	GO:0060047	heart contraction
0.41	GO:0055006	cardiac cell development
0.41	GO:0003208	cardiac ventricle morphogenesis
0.41	GO:0048747	muscle fiber development
0.41	GO:0030239	myofibril assembly

0.70	GO:0005509	calcium ion binding
0.55	GO:0008307	structural constituent of muscle
0.41	GO:0003785	actin monomer binding

0.43	GO:0015629	actin cytoskeleton
0.43	GO:0043292	contractile fiber
0.39	GO:0044430	cytoskeletal part
0.37	GO:0043234	protein complex
0.36	GO:0005765	lysosomal membrane
0.33	GO:0005829	cytosol
0.32	GO:0005739	mitochondrion

sp|P04468|CASK_RAT
Kappa-casein
Search

CSN3

0.94	Kappa-casein

0.71	GO:0007595	lactation
0.65	GO:0050821	protein stabilization
0.41	GO:1903496	response to 11-deoxycorticosterone
0.41	GO:1903494	response to dehydroepiandrosterone
0.40	GO:0032570	response to progesterone
0.40	GO:0032355	response to estradiol
0.38	GO:0051260	protein homooligomerization

0.41	GO:0035375	zymogen binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.40	GO:0005796	Golgi lumen

sp|P04474|PRP3_RAT
Acidic proline-rich protein PRP33
Search

0.57	Proline-rich proteoglycan 2

0.49	GO:0007269	neurotransmitter secretion
0.40	GO:0036211	protein modification process
0.39	GO:0016310	phosphorylation
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0097091	synaptic vesicle clustering
0.36	GO:0006325	chromatin organization
0.36	GO:0050829	defense response to Gram-negative bacterium
0.36	GO:0050794	regulation of cellular process
0.36	GO:0006508	proteolysis
0.36	GO:0010556	regulation of macromolecule biosynthetic process

0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0003713	transcription coactivator activity
0.38	GO:0052861	glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group
0.38	GO:0005515	protein binding
0.38	GO:0005509	calcium ion binding
0.37	GO:0005544	calcium-dependent phospholipid binding

0.49	GO:0008021	synaptic vesicle
0.46	GO:0005576	extracellular region
0.39	GO:0044454	nuclear chromosome part
0.38	GO:0099501	exocytic vesicle membrane
0.37	GO:0000794	condensed nuclear chromosome
0.37	GO:0005856	cytoskeleton
0.37	GO:0014069	postsynaptic density
0.37	GO:0048786	presynaptic active zone
0.37	GO:0043209	myelin sheath
0.37	GO:0030424	axon

0.40

GO:0004674

sp|P04550|PTMS_RAT
Parathymosin
Search

PTMS

0.97	Parathymosin

0.51	GO:0002376	immune system process
0.44	GO:0045905	positive regulation of translational termination
0.44	GO:0045901	positive regulation of translational elongation
0.44	GO:0006452	translational frameshifting
0.42	GO:0042254	ribosome biogenesis
0.41	GO:0050790	regulation of catalytic activity
0.41	GO:0060195	negative regulation of antisense RNA transcription
0.40	GO:0006260	DNA replication
0.40	GO:0044092	negative regulation of molecular function
0.40	GO:0006886	intracellular protein transport

0.42	GO:0008270	zinc ion binding
0.42	GO:0008135	translation factor activity, RNA binding
0.42	GO:0030234	enzyme regulator activity
0.41	GO:0043022	ribosome binding
0.39	GO:1901265	nucleoside phosphate binding
0.39	GO:0008144	drug binding
0.39	GO:0097367	carbohydrate derivative binding
0.38	GO:0043168	anion binding
0.38	GO:0036094	small molecule binding
0.37	GO:0008565	protein transporter activity

0.47	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.39	GO:0043234	protein complex
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:1990234	transferase complex
0.36	GO:0030686	90S preribosome

0.36

GO:0016779

sp|P04563|GAST_RAT
Gastrin
Search

GAST

0.97

Gastrin

0.75	GO:0010469	regulation of receptor activity
0.63	GO:0032094	response to food
0.51	GO:0007186	G-protein coupled receptor signaling pathway

0.78

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P04631|S100B_RAT
Protein S100-B
Search

S100B

0.41	S100 calcium binding protein B

0.53	GO:0048168	regulation of neuronal synaptic plasticity
0.52	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.52	GO:0007613	memory
0.49	GO:0050727	regulation of inflammatory response
0.48	GO:0045087	innate immune response
0.42	GO:0048708	astrocyte differentiation
0.42	GO:0031643	positive regulation of myelination
0.42	GO:0051597	response to methylmercury
0.42	GO:2001015	negative regulation of skeletal muscle cell differentiation
0.41	GO:0060291	long-term synaptic potentiation

0.70	GO:0005509	calcium ion binding
0.63	GO:0050786	RAGE receptor binding
0.63	GO:0008270	zinc ion binding
0.56	GO:0044548	S100 protein binding
0.55	GO:0048306	calcium-dependent protein binding
0.52	GO:0035662	Toll-like receptor 4 binding
0.52	GO:0050544	arachidonic acid binding
0.51	GO:0042803	protein homodimerization activity
0.48	GO:0008092	cytoskeletal protein binding
0.35	GO:0019210	kinase inhibitor activity

0.54	GO:0001726	ruffle
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0043025	neuronal cell body
0.45	GO:0005634	nucleus
0.40	GO:0005576	extracellular region
0.39	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0005829	cytosol
0.37	GO:0012505	endomembrane system
0.36	GO:0045178	basal part of cell
0.36	GO:0031967	organelle envelope

sp|P04633|UCP1_RAT
Mitochondrial brown fat uncoupling protein 1
Search

UCP1

0.87	Mitochondrial brown fat uncoupling protein 1

0.76	GO:0006839	mitochondrial transport
0.62	GO:1990845	adaptive thermogenesis
0.56	GO:0070542	response to fatty acid
0.55	GO:1903426	regulation of reactive oxygen species biosynthetic process
0.53	GO:0009266	response to temperature stimulus
0.53	GO:0002021	response to dietary excess
0.53	GO:0071229	cellular response to acid chemical
0.53	GO:0050873	brown fat cell differentiation
0.52	GO:0000302	response to reactive oxygen species
0.51	GO:0071396	cellular response to lipid

0.64	GO:0017077	oxidative phosphorylation uncoupler activity
0.57	GO:0036041	long-chain fatty acid binding
0.48	GO:1901612	cardiolipin binding
0.41	GO:0032555	purine ribonucleotide binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0031966	mitochondrial membrane
0.47	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|P04634|LIPG_RAT
Gastric triacylglycerol lipase
Search

0.60	Lipase A, lysosomal acid type

0.44	GO:0048873	homeostasis of number of cells within a tissue
0.43	GO:0048771	tissue remodeling
0.43	GO:0001816	cytokine production
0.43	GO:0030324	lung development
0.42	GO:0006954	inflammatory response
0.42	GO:0008283	cell proliferation
0.41	GO:0000902	cell morphogenesis
0.36	GO:0006629	lipid metabolic process

0.60

GO:0016788

hydrolase activity, acting on ester bonds

0.43

GO:0001650

fibrillar center

0.60

EC:3.1

GO:0016788

sp|P04636|MDHM_RAT
Malate dehydrogenase, mitochondrial
Search

MDH2

0.46	Malate dehydrogenase, mitochondrial

0.78	GO:0006108	malate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0005975	carbohydrate metabolic process
0.52	GO:0006475	internal protein amino acid acetylation
0.39	GO:0006734	NADH metabolic process
0.38	GO:0006107	oxaloacetate metabolic process
0.33	GO:0044283	small molecule biosynthetic process
0.32	GO:1901576	organic substance biosynthetic process

0.79	GO:0030060	L-malate dehydrogenase activity
0.40	GO:0046554	malate dehydrogenase (NADP+) activity
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0043621	protein self-association
0.34	GO:0051087	chaperone binding
0.34	GO:0003723	RNA binding

0.52	GO:0043209	myelin sheath
0.45	GO:0044429	mitochondrial part
0.44	GO:0019866	organelle inner membrane
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.79	EC:1.1.1.37	GO:0030060
0.40	KEGG:R00343	GO:0046554

sp|P04638|APOA2_RAT
Apolipoprotein A-II
Search

APOA2

0.97	Apolipoprotein A-II

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.72	GO:0060695	negative regulation of cholesterol transporter activity
0.71	GO:0018158	protein oxidation
0.71	GO:0060621	negative regulation of cholesterol import
0.71	GO:0045416	positive regulation of interleukin-8 biosynthetic process
0.70	GO:0046340	diacylglycerol catabolic process
0.70	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
0.70	GO:0034380	high-density lipoprotein particle assembly
0.70	GO:0034374	low-density lipoprotein particle remodeling

0.72	GO:0008289	lipid binding
0.71	GO:0070653	high-density lipoprotein particle receptor binding
0.71	GO:0034190	apolipoprotein receptor binding
0.70	GO:0008035	high-density lipoprotein particle binding
0.69	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.68	GO:0050997	quaternary ammonium group binding
0.67	GO:0055102	lipase inhibitor activity
0.67	GO:0017127	cholesterol transporter activity
0.64	GO:0070405	ammonium ion binding
0.64	GO:0043178	alcohol binding

0.75	GO:0034364	high-density lipoprotein particle
0.68	GO:0042627	chylomicron
0.68	GO:0034361	very-low-density lipoprotein particle
0.55	GO:0072562	blood microparticle
0.41	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol
0.37	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005769	early endosome

sp|P04639|APOA1_RAT
Apolipoprotein A-I
Search

APOA1

0.96	apolipoprotein A-I precursor

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.73	GO:0008203	cholesterol metabolic process
0.73	GO:0060354	negative regulation of cell adhesion molecule production
0.73	GO:0030300	regulation of intestinal cholesterol absorption
0.72	GO:0018158	protein oxidation
0.72	GO:0034380	high-density lipoprotein particle assembly
0.72	GO:0010873	positive regulation of cholesterol esterification
0.72	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
0.71	GO:0050713	negative regulation of interleukin-1 beta secretion

0.74	GO:0070653	high-density lipoprotein particle receptor binding
0.73	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.72	GO:0008289	lipid binding
0.72	GO:0008035	high-density lipoprotein particle binding
0.72	GO:0034191	apolipoprotein A-I receptor binding
0.70	GO:0045499	chemorepellent activity
0.70	GO:0017127	cholesterol transporter activity
0.68	GO:0001540	amyloid-beta binding
0.66	GO:0043178	alcohol binding
0.61	GO:0031072	heat shock protein binding

0.76	GO:0034364	high-density lipoprotein particle
0.69	GO:0034385	triglyceride-rich plasma lipoprotein particle
0.64	GO:0030139	endocytic vesicle
0.59	GO:0031012	extracellular matrix
0.52	GO:0042627	chylomicron
0.51	GO:0072562	blood microparticle
0.44	GO:0034362	low-density lipoprotein particle
0.40	GO:0009986	cell surface
0.40	GO:0070062	extracellular exosome
0.37	GO:0034774	secretory granule lumen

sp|P04640|OSTCN_RAT
Osteocalcin
Search

BGLAP

0.97	Osteocalcin

0.85	GO:0030500	regulation of bone mineralization
0.65	GO:0033280	response to vitamin D
0.63	GO:0031214	biomineral tissue development
0.63	GO:0001649	osteoblast differentiation
0.43	GO:0033594	response to hydroxyisoflavone
0.43	GO:0032571	response to vitamin K
0.42	GO:0033574	response to testosterone
0.42	GO:0071295	cellular response to vitamin
0.42	GO:0014823	response to activity
0.42	GO:0071363	cellular response to growth factor stimulus

0.70	GO:0005509	calcium ion binding
0.44	GO:0008147	structural constituent of bone
0.42	GO:0046848	hydroxyapatite binding
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0046914	transition metal ion binding

0.66	GO:0005576	extracellular region
0.44	GO:0005737	cytoplasm
0.41	GO:0043204	perikaryon
0.40	GO:0030425	dendrite
0.38	GO:0031982	vesicle
0.38	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|P04642|LDHA_RAT
L-lactate dehydrogenase A chain
Search

LDHA

0.54	L-lactate dehydrogenase A chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.38	GO:0051591	response to cAMP
0.38	GO:0043627	response to estrogen
0.37	GO:0009749	response to glucose
0.37	GO:0042542	response to hydrogen peroxide
0.37	GO:0048569	post-embryonic animal organ development
0.37	GO:0001666	response to hypoxia
0.37	GO:0007584	response to nutrient

0.81	GO:0004459	L-lactate dehydrogenase activity
0.42	GO:0045296	cadherin binding
0.37	GO:0019900	kinase binding
0.36	GO:0042802	identical protein binding
0.35	GO:0051287	NAD binding

0.48	GO:0005737	cytoplasm
0.37	GO:0035686	sperm fibrous sheath
0.36	GO:0070062	extracellular exosome
0.36	GO:0000439	core TFIIH complex
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P04644|RS17_RAT
40S ribosomal protein S17
Search

RPS17

0.71	Ribosomal protein S17

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000028	ribosomal small subunit assembly
0.47	GO:0034101	erythrocyte homeostasis
0.42	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0045182	translation regulator activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

sp|P04646|RL35A_RAT
60S ribosomal protein L35a
Search

RPL35A

0.67	Ribosomal protein L35

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0042273	ribosomal large subunit biogenesis
0.43	GO:0016072	rRNA metabolic process
0.43	GO:0030218	erythrocyte differentiation
0.41	GO:0043009	chordate embryonic development
0.36	GO:0007155	cell adhesion
0.35	GO:0006508	proteolysis

0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0000049	tRNA binding
0.36	GO:0004222	metalloendopeptidase activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0030234	enzyme regulator activity
0.33	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005739	mitochondrion
0.35	GO:0031012	extracellular matrix
0.34	GO:0070062	extracellular exosome
0.33	GO:1905369	endopeptidase complex
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.36

GO:0004222

sp|P04652|TSHB_RAT
Thyrotropin subunit beta
Search

TSHB

0.86	Thyroid stimulating hormone beta subunit

0.76	GO:0010469	regulation of receptor activity
0.40	GO:0010033	response to organic substance
0.39	GO:0071495	cellular response to endogenous stimulus
0.39	GO:0007267	cell-cell signaling
0.38	GO:0033273	response to vitamin
0.38	GO:0043627	response to estrogen
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0051592	response to calcium ion
0.37	GO:0070887	cellular response to chemical stimulus

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P04692|TPM1_RAT
Tropomyosin alpha-1 chain
Search

TPM1

0.87	Tropomyosin alpha-1 chain

0.75	GO:0060048	cardiac muscle contraction
0.71	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.70	GO:1904753	negative regulation of vascular associated smooth muscle cell migration
0.68	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.65	GO:0045214	sarcomere organization
0.61	GO:0003065	positive regulation of heart rate by epinephrine
0.59	GO:0034614	cellular response to reactive oxygen species
0.55	GO:0008360	regulation of cell shape
0.54	GO:0007015	actin filament organization
0.52	GO:0001701	in utero embryonic development

0.64	GO:0008307	structural constituent of muscle
0.63	GO:0008092	cytoskeletal protein binding
0.58	GO:0032403	protein complex binding
0.53	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.47	GO:0097718	disordered domain specific binding
0.44	GO:0005200	structural constituent of cytoskeleton
0.42	GO:0047485	protein N-terminus binding

0.74	GO:0015629	actin cytoskeleton
0.70	GO:0032059	bleb
0.65	GO:0032587	ruffle membrane
0.63	GO:0044430	cytoskeletal part
0.62	GO:0030016	myofibril
0.62	GO:0005829	cytosol
0.60	GO:0044449	contractile fiber part
0.42	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P04694|ATTY_RAT
Tyrosine aminotransferase
Search

TAT

0.87	Tyrosine aminotransferase

0.71	GO:0009074	aromatic amino acid family catabolic process
0.55	GO:0006103	2-oxoglutarate metabolic process
0.53	GO:0006570	tyrosine metabolic process
0.51	GO:0006536	glutamate metabolic process
0.49	GO:1901606	alpha-amino acid catabolic process
0.48	GO:0009058	biosynthetic process
0.38	GO:0051384	response to glucocorticoid
0.38	GO:0006558	L-phenylalanine metabolic process
0.38	GO:0046689	response to mercury ion
0.37	GO:0042737	drug catabolic process

0.85	GO:0070547	L-tyrosine aminotransferase activity
0.65	GO:0030170	pyridoxal phosphate binding
0.39	GO:0070546	L-phenylalanine aminotransferase activity
0.38	GO:0016597	amino acid binding
0.34	GO:0005515	protein binding

0.45	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P04757|ACHA3_RAT
Neuronal acetylcholine receptor subunit alpha-3
Search

CHRNA3

0.89	Cholinergic receptor nicotinic alpha 3 subunit

0.80	GO:0060079	excitatory postsynaptic potential
0.66	GO:0060084	synaptic transmission involved in micturition
0.65	GO:0035095	behavioral response to nicotine
0.60	GO:0034220	ion transmembrane transport
0.55	GO:0007399	nervous system development
0.41	GO:0006812	cation transport
0.38	GO:0007271	synaptic transmission, cholinergic

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.51	GO:0022850	serotonin-gated cation-selective channel activity
0.39	GO:0042166	acetylcholine binding
0.35	GO:0051537	2 iron, 2 sulfur cluster binding

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.63	GO:0005892	acetylcholine-gated channel complex

sp|P04762|CATA_RAT
Catalase
Search

CAT

0.54

Catalase

0.76	GO:0042744	hydrogen peroxide catabolic process
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.55	GO:0009650	UV protection
0.55	GO:0020027	hemoglobin metabolic process
0.53	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.53	GO:0051289	protein homotetramerization
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.52	GO:0055114	oxidation-reduction process

0.77	GO:0004096	catalase activity
0.63	GO:0020037	heme binding
0.53	GO:0004046	aminoacylase activity
0.53	GO:0046872	metal ion binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0005102	receptor binding
0.47	GO:0019899	enzyme binding
0.47	GO:0050661	NADP binding
0.35	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity

0.52	GO:0005777	peroxisome
0.51	GO:0031903	microbody membrane
0.44	GO:0005739	mitochondrion
0.37	GO:0031970	organelle envelope lumen
0.37	GO:0005764	lysosome
0.36	GO:0005615	extracellular space
0.36	GO:0005925	focal adhesion
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum

0.77

EC:1.11.1.6

GO:0004096

sp|P04764|ENOA_RAT
Alpha-enolase
Search

ENO1

0.72	Alpha-enolase

0.71	GO:0006096	glycolytic process
0.51	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.51	GO:0010756	positive regulation of plasminogen activation
0.50	GO:0061718	glucose catabolic process to pyruvate
0.50	GO:2001171	positive regulation of ATP biosynthetic process
0.50	GO:0006735	NADH regeneration
0.50	GO:1900038	negative regulation of cellular response to hypoxia
0.49	GO:0045933	positive regulation of muscle contraction
0.48	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.48	GO:0030308	negative regulation of cell growth

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0045296	cadherin binding
0.46	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.45	GO:0042803	protein homodimerization activity
0.45	GO:0051020	GTPase binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0003723	RNA binding
0.34	GO:0005212	structural constituent of eye lens

0.77	GO:0000015	phosphopyruvate hydratase complex
0.48	GO:0099738	cell cortex region
0.45	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.39	GO:0043209	myelin sheath
0.37	GO:0019898	extrinsic component of membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0097458	neuron part
0.35	GO:0031430	M band
0.34	GO:0098857	membrane microdomain

0.78

EC:4.2.1.11

GO:0004634

sp|P04774|SCN1A_RAT
Sodium channel protein type 1 subunit alpha
Search

0.66	Sodium channel protein type 1 subunit alpha

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.59	GO:0019228	neuronal action potential
0.54	GO:0086010	membrane depolarization during action potential
0.52	GO:0098870	action potential propagation
0.52	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.52	GO:0086002	cardiac muscle cell action potential involved in contraction
0.51	GO:0050884	neuromuscular process controlling posture
0.51	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress
0.51	GO:0007628	adult walking behavior

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.36	GO:0031402	sodium ion binding
0.35	GO:0043522	leucine zipper domain binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.58	GO:0030315	T-tubule
0.58	GO:0014704	intercalated disc
0.57	GO:0044304	main axon
0.49	GO:0030018	Z disc
0.48	GO:0043025	neuronal cell body
0.48	GO:0016604	nuclear body

sp|P04775|SCN2A_RAT
Sodium channel protein type 2 subunit alpha
Search

SCN2A

0.66	Sodium channel protein type 2 subunit alpha

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.57	GO:0019228	neuronal action potential
0.54	GO:0086010	membrane depolarization during action potential
0.52	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress
0.50	GO:0051402	neuron apoptotic process
0.48	GO:0098870	action potential propagation
0.48	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.48	GO:0086002	cardiac muscle cell action potential involved in contraction
0.48	GO:0050884	neuromuscular process controlling posture

0.84	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.36	GO:0031402	sodium ion binding
0.35	GO:0043522	leucine zipper domain binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.56	GO:0030315	T-tubule
0.56	GO:0014704	intercalated disc
0.55	GO:0044304	main axon
0.46	GO:0030018	Z disc
0.45	GO:0043025	neuronal cell body
0.44	GO:0016604	nuclear body

sp|P04785|PDIA1_RAT
Protein disulfide-isomerase
Search

P4HB

0.48	Dolichyl-diphosphooligosaccharide--protein glycotransferase

0.68	GO:0045454	cell redox homeostasis
0.57	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.56	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
0.56	GO:0046598	positive regulation of viral entry into host cell
0.53	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0071456	cellular response to hypoxia
0.42	GO:0006457	protein folding
0.41	GO:0055114	oxidation-reduction process
0.36	GO:0034378	chylomicron assembly
0.36	GO:0038155	interleukin-23-mediated signaling pathway

0.79	GO:0003756	protein disulfide isomerase activity
0.56	GO:0031545	peptidyl-proline 4-dioxygenase activity
0.54	GO:0019798	procollagen-proline dioxygenase activity
0.53	GO:0005178	integrin binding
0.52	GO:0015037	peptide disulfide oxidoreductase activity
0.51	GO:0046982	protein heterodimerization activity
0.37	GO:0019899	enzyme binding
0.34	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.69	GO:0005783	endoplasmic reticulum
0.52	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0009897	external side of plasma membrane
0.47	GO:1990204	oxidoreductase complex
0.43	GO:0042470	melanosome
0.43	GO:0044446	intracellular organelle part
0.43	GO:0043234	protein complex
0.40	GO:0043233	organelle lumen
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.79

EC:5.3.4.1

GO:0003756

sp|P04797|G3P_RAT
Glyceraldehyde-3-phosphate dehydrogenase
Search

GAPDH

0.52	Glyceraldehyde-3-phosphate dehydrogenase

0.68	GO:0006006	glucose metabolic process
0.67	GO:0006757	ATP generation from ADP
0.65	GO:0006090	pyruvate metabolic process
0.64	GO:0016052	carbohydrate catabolic process
0.64	GO:0019362	pyridine nucleotide metabolic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.48	GO:0051402	neuron apoptotic process
0.46	GO:0051873	killing by host of symbiont cells
0.46	GO:0050821	protein stabilization

0.78	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.66	GO:0050661	NADP binding
0.64	GO:0051287	NAD binding
0.51	GO:0035605	peptidyl-cysteine S-nitrosylase activity
0.47	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.45	GO:0097718	disordered domain specific binding
0.44	GO:0008017	microtubule binding
0.41	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding

0.52	GO:0097452	GAIT complex
0.45	GO:0005829	cytosol
0.44	GO:0005811	lipid droplet
0.43	GO:0015630	microtubule cytoskeleton
0.43	GO:0031965	nuclear membrane
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome

0.78

EC:1.2.1.12

GO:0004365

sp|P04799|CP1A2_RAT
Cytochrome P450 1A2
Search

sp|P04800|CP3A1_RAT
Cytochrome P450 3A1
Search

0.79	Cytochrome P450 family 3 subfamily A polypeptide 4

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0002933	lipid hydroxylation
0.49	GO:0009822	alkaloid catabolic process
0.48	GO:0008202	steroid metabolic process
0.46	GO:0070988	demethylation
0.42	GO:0016098	monoterpenoid metabolic process
0.42	GO:0042738	exogenous drug catabolic process
0.42	GO:0042445	hormone metabolic process
0.42	GO:0042362	fat-soluble vitamin biosynthetic process
0.40	GO:1901615	organic hydroxy compound metabolic process

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.54	GO:0008395	steroid hydroxylase activity
0.43	GO:0030343	vitamin D3 25-hydroxylase activity
0.43	GO:0034875	caffeine oxidase activity
0.43	GO:0070576	vitamin D 24-hydroxylase activity
0.40	GO:0005496	steroid binding
0.38	GO:0019899	enzyme binding
0.37	GO:0032451	demethylase activity

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.14.14	GO:0016712
0.35	KEGG:R07203	GO:0033777

sp|P04812|SVS5_RAT
Seminal vesicle secretory protein 5
Search

SVS5

0.95	Seminal vesicle secretory protein 5

0.73

GO:0005615

extracellular space

sp|P04823|IL3_RAT
Interleukin-3
Search

IL3

0.83	Interleukin-3

0.77	GO:0038156	interleukin-3-mediated signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.75	GO:0033026	negative regulation of mast cell apoptotic process
0.74	GO:0070668	positive regulation of mast cell proliferation
0.74	GO:0033028	myeloid cell apoptotic process
0.74	GO:0006955	immune response
0.73	GO:0042976	activation of Janus kinase activity
0.71	GO:1903131	mononuclear cell differentiation
0.70	GO:0038034	signal transduction in absence of ligand
0.70	GO:0006110	regulation of glycolytic process

0.88	GO:0005135	interleukin-3 receptor binding
0.81	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.64	GO:0005149	interleukin-1 receptor binding

0.73

GO:0005615

extracellular space

sp|P04897|GNAI2_RAT
Guanine nucleotide-binding protein G(i) subunit alpha-2
Search

GNAI2

0.93	Guanine nucleotide binding protein alpha inhibiting 2

0.81	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.51	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.49	GO:0008283	cell proliferation
0.48	GO:0001973	adenosine receptor signaling pathway
0.47	GO:0007214	gamma-aminobutyric acid signaling pathway
0.47	GO:0051301	cell division
0.38	GO:0050805	negative regulation of synaptic transmission
0.38	GO:0007049	cell cycle
0.37	GO:0000186	activation of MAPKK activity
0.37	GO:0051924	regulation of calcium ion transport

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0001664	G-protein coupled receptor binding
0.35	GO:0046872	metal ion binding

0.54	GO:0030496	midbody
0.51	GO:0005813	centrosome
0.50	GO:0030425	dendrite
0.50	GO:0044297	cell body
0.47	GO:1905360	GTPase complex
0.47	GO:0005654	nucleoplasm
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0005829	cytosol
0.42	GO:0098797	plasma membrane protein complex
0.37	GO:0045121	membrane raft

sp|P04905|GSTM1_RAT
Glutathione S-transferase Mu 1
Search

0.44	Glutathione S-transferase mu

0.53	GO:0018916	nitrobenzene metabolic process
0.50	GO:0006749	glutathione metabolic process
0.48	GO:0070458	cellular detoxification of nitrogen compound
0.47	GO:0042178	xenobiotic catabolic process
0.44	GO:0035690	cellular response to drug
0.42	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.42	GO:0071415	cellular response to purine-containing compound
0.42	GO:0043651	linoleic acid metabolic process
0.42	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.42	GO:0031000	response to caffeine

0.78	GO:0004364	glutathione transferase activity
0.51	GO:0043295	glutathione binding
0.50	GO:0042802	identical protein binding
0.45	GO:0046983	protein dimerization activity
0.45	GO:0019899	enzyme binding
0.40	GO:0004602	glutathione peroxidase activity
0.38	GO:0005102	receptor binding
0.35	GO:0005496	steroid binding
0.34	GO:0016151	nickel cation binding
0.33	GO:0003735	structural constituent of ribosome

0.54	GO:0045171	intercellular bridge
0.48	GO:0005829	cytosol
0.41	GO:0016529	sarcoplasmic reticulum
0.38	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex
0.33	GO:0005840	ribosome
0.32	GO:0005886	plasma membrane

0.78

GO:0004364

sp|P04906|GSTP1_RAT
Glutathione S-transferase P
Search

GSTP1

0.69	Glutathione S-transferase pi

0.56	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
0.55	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.55	GO:0043508	negative regulation of JUN kinase activity
0.55	GO:0032691	negative regulation of interleukin-1 beta production
0.54	GO:0043651	linoleic acid metabolic process
0.53	GO:0032720	negative regulation of tumor necrosis factor production
0.53	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.50	GO:0071466	cellular response to xenobiotic stimulus
0.50	GO:0006749	glutathione metabolic process

0.76	GO:0004364	glutathione transferase activity
0.58	GO:0035730	S-nitrosoglutathione binding
0.51	GO:0035731	dinitrosyl-iron complex binding
0.51	GO:0004602	glutathione peroxidase activity
0.41	GO:0008432	JUN kinase binding
0.39	GO:0019207	kinase regulator activity
0.39	GO:0043295	glutathione binding
0.37	GO:0070026	nitric oxide binding
0.35	GO:0008144	drug binding

0.57	GO:0097057	TRAF2-GSTP1 complex
0.46	GO:0005829	cytosol
0.45	GO:0005739	mitochondrion
0.42	GO:0098788	dendritic knob
0.41	GO:0005634	nucleus
0.40	GO:0071683	sensory dendrite
0.39	GO:0097014	ciliary plasm
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0070062	extracellular exosome
0.37	GO:1904813	ficolin-1-rich granule lumen

0.76

GO:0004364

sp|P04916|RET4_RAT
Retinol-binding protein 4
Search

RBP4

0.97	Plasma retinol binding protein 4

0.86	GO:0034633	retinol transport
0.55	GO:0032526	response to retinoic acid
0.55	GO:0030277	maintenance of gastrointestinal epithelium
0.54	GO:0042572	retinol metabolic process
0.54	GO:0032024	positive regulation of insulin secretion
0.53	GO:0001654	eye development
0.52	GO:0042593	glucose homeostasis
0.48	GO:0019319	hexose biosynthetic process
0.47	GO:0006006	glucose metabolic process
0.39	GO:0060157	urinary bladder development

0.86	GO:0034632	retinol transmembrane transporter activity
0.83	GO:0005501	retinoid binding
0.54	GO:0043178	alcohol binding
0.46	GO:0019842	vitamin binding
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0019904	protein domain specific binding
0.33	GO:0005102	receptor binding

0.50	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0060418	yolk plasma
0.35	GO:0043234	protein complex
0.34	GO:0030136	clathrin-coated vesicle
0.34	GO:0033165	interphotoreceptor matrix
0.33	GO:0005829	cytosol

sp|P04917|SRGN_RAT
Serglycin
Search

SRGN

0.86

Serglycin

0.86	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.86	GO:0030502	negative regulation of bone mineralization
0.78	GO:0033366	protein localization to secretory granule
0.77	GO:0033364	mast cell secretory granule organization
0.68	GO:0033371	T cell secretory granule organization
0.61	GO:0050710	negative regulation of cytokine secretion
0.58	GO:0051651	maintenance of location in cell
0.58	GO:0045185	maintenance of protein location
0.55	GO:0016485	protein processing
0.55	GO:0031214	biomineral tissue development

0.49	GO:0005518	collagen binding
0.35	GO:0009055	electron transfer activity

0.71	GO:0005615	extracellular space
0.70	GO:0005794	Golgi apparatus
0.62	GO:0042629	mast cell granule
0.52	GO:0042588	zymogen granule
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.44	GO:0031093	platelet alpha granule lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P04937|FINC_RAT
Fibronectin
Search

FN1

0.49	Fibronectin

0.62	GO:1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate
0.62	GO:2001202	negative regulation of transforming growth factor-beta secretion
0.61	GO:0007161	calcium-independent cell-matrix adhesion
0.61	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction
0.60	GO:0033622	integrin activation
0.58	GO:0045773	positive regulation of axon extension
0.58	GO:0048146	positive regulation of fibroblast proliferation
0.58	GO:0035987	endodermal cell differentiation
0.58	GO:0007044	cell-substrate junction assembly
0.58	GO:0034446	substrate adhesion-dependent cell spreading

0.58	GO:0097718	disordered domain specific binding
0.57	GO:0005178	integrin binding
0.57	GO:0002020	protease binding
0.56	GO:0016504	peptidase activator activity
0.56	GO:0008022	protein C-terminus binding
0.53	GO:0051087	chaperone binding
0.51	GO:0042802	identical protein binding
0.39	GO:0008201	heparin binding
0.35	GO:0045340	mercury ion binding
0.35	GO:0005201	extracellular matrix structural constituent

0.66	GO:0005576	extracellular region
0.56	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.55	GO:0016324	apical plasma membrane
0.51	GO:0031982	vesicle
0.44	GO:0043234	protein complex
0.33	GO:0005788	endoplasmic reticulum lumen

sp|P04961|PCNA_RAT
Proliferating cell nuclear antigen
Search

PCNA

0.66	Proliferating cell nuclear antigen

0.76	GO:0006275	regulation of DNA replication
0.65	GO:0006260	DNA replication
0.58	GO:0019985	translesion synthesis
0.58	GO:0032077	positive regulation of deoxyribonuclease activity
0.56	GO:0045739	positive regulation of DNA repair
0.55	GO:0034644	cellular response to UV
0.53	GO:0030855	epithelial cell differentiation
0.52	GO:0006298	mismatch repair
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process

0.84	GO:0030337	DNA polymerase processivity factor activity
0.60	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity
0.59	GO:0032405	MutLalpha complex binding
0.58	GO:0032139	dinucleotide insertion or deletion binding
0.57	GO:0070182	DNA polymerase binding
0.57	GO:0035035	histone acetyltransferase binding
0.56	GO:0030971	receptor tyrosine kinase binding
0.52	GO:0003682	chromatin binding
0.50	GO:0042802	identical protein binding
0.50	GO:0003684	damaged DNA binding

0.61	GO:0070557	PCNA-p21 complex
0.60	GO:0043626	PCNA complex
0.54	GO:0043596	nuclear replication fork
0.52	GO:0005813	centrosome
0.52	GO:0016604	nuclear body
0.38	GO:0005652	nuclear lamina
0.38	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.36	GO:0000784	nuclear chromosome, telomeric region
0.36	GO:0070062	extracellular exosome
0.35	GO:0005663	DNA replication factor C complex

0.60

EC:3.2.2

GO:0000701

sp|P05011|IFNA1_RAT
Interferon alpha-1
Search

0.94	Interferon alpha B

0.78	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.60	GO:0002323	natural killer cell activation involved in immune response
0.59	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.58	GO:0042100	B cell proliferation
0.58	GO:0002286	T cell activation involved in immune response
0.57	GO:0043330	response to exogenous dsRNA
0.57	GO:0030183	B cell differentiation
0.55	GO:0002250	adaptive immune response
0.55	GO:0006959	humoral immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.52	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P05065|ALDOA_RAT
Fructose-bisphosphate aldolase A
Search

ALDOA

0.54	Fructose-bisphosphate aldolase A

0.71	GO:0006096	glycolytic process
0.55	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.48	GO:0046716	muscle cell cellular homeostasis
0.48	GO:0007339	binding of sperm to zona pellucida
0.47	GO:0006000	fructose metabolic process
0.47	GO:0006941	striated muscle contraction
0.47	GO:0030855	epithelial cell differentiation
0.43	GO:0006754	ATP biosynthetic process
0.42	GO:0008360	regulation of cell shape
0.41	GO:0051289	protein homotetramerization

0.79	GO:0004332	fructose-bisphosphate aldolase activity
0.50	GO:0070061	fructose binding
0.49	GO:0008092	cytoskeletal protein binding
0.46	GO:0045296	cadherin binding
0.37	GO:0042802	identical protein binding
0.36	GO:0002020	protease binding
0.35	GO:0061609	fructose-1-phosphate aldolase activity
0.35	GO:0051117	ATPase binding
0.34	GO:0003723	RNA binding
0.33	GO:0004672	protein kinase activity

0.49	GO:0061827	sperm head
0.46	GO:0070062	extracellular exosome
0.44	GO:0015629	actin cytoskeleton
0.43	GO:0005829	cytosol
0.41	GO:0031430	M band
0.41	GO:0005739	mitochondrion
0.40	GO:0031674	I band
0.40	GO:0035686	sperm fibrous sheath
0.37	GO:1904724	tertiary granule lumen
0.37	GO:1904813	ficolin-1-rich granule lumen

0.79

EC:4.1.2.13

GO:0004332

sp|P05178|CP2C6_RAT
Cytochrome P450 2C6
Search

0.96	Cytochrome P450 family 2 subfamily C polypeptide 9

0.56	GO:0042738	exogenous drug catabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0002933	lipid hydroxylation
0.50	GO:0008202	steroid metabolic process
0.49	GO:0070988	demethylation
0.47	GO:0016098	monoterpenoid metabolic process
0.46	GO:0019373	epoxygenase P450 pathway
0.39	GO:0097267	omega-hydroxylase P450 pathway
0.39	GO:0019627	urea metabolic process
0.37	GO:0006805	xenobiotic metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.54	GO:0034875	caffeine oxidase activity
0.38	GO:0019899	enzyme binding
0.37	GO:0019825	oxygen binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P05179|CP2C7_RAT
Cytochrome P450 2C7
Search

0.95	Cytochrome P450 family 2 subfamily C polypeptide 9

0.56	GO:0042738	exogenous drug catabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0019373	epoxygenase P450 pathway
0.49	GO:0002933	lipid hydroxylation
0.49	GO:0008202	steroid metabolic process
0.48	GO:0070988	demethylation
0.48	GO:0016098	monoterpenoid metabolic process
0.42	GO:0097267	omega-hydroxylase P450 pathway
0.39	GO:0006805	xenobiotic metabolic process
0.39	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.54	GO:0034875	caffeine oxidase activity
0.39	GO:0019899	enzyme binding
0.39	GO:0019825	oxygen binding

0.45	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P05182|CP2E1_RAT
Cytochrome P450 2E1
Search

CYP2E1

0.85	Cytochrome P450 family 2 subfamily e polypeptide 1

0.56	GO:0019373	epoxygenase P450 pathway
0.55	GO:0016098	monoterpenoid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0008202	steroid metabolic process
0.42	GO:0017144	drug metabolic process
0.40	GO:0010193	response to ozone
0.39	GO:0045471	response to ethanol
0.38	GO:0006805	xenobiotic metabolic process
0.38	GO:0006641	triglyceride metabolic process
0.38	GO:0010243	response to organonitrogen compound

0.70	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.57	GO:0008392	arachidonic acid epoxygenase activity
0.54	GO:0008395	steroid hydroxylase activity
0.46	GO:0019899	enzyme binding
0.40	GO:0019825	oxygen binding
0.37	GO:0071614	linoleic acid epoxygenase activity
0.37	GO:0034875	caffeine oxidase activity
0.34	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

0.48	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.37	GO:0044431	Golgi apparatus part
0.35	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.70

GO:0016712

sp|P05183|CP3A2_RAT
Cytochrome P450 3A2
Search

0.78	Cytochrome P450 family 3 subfamily A polypeptide 4

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0002933	lipid hydroxylation
0.49	GO:0009822	alkaloid catabolic process
0.48	GO:0008202	steroid metabolic process
0.46	GO:0070988	demethylation
0.42	GO:0016098	monoterpenoid metabolic process
0.42	GO:0042738	exogenous drug catabolic process
0.42	GO:0042445	hormone metabolic process
0.42	GO:0042362	fat-soluble vitamin biosynthetic process
0.41	GO:1901615	organic hydroxy compound metabolic process

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.54	GO:0008395	steroid hydroxylase activity
0.43	GO:0030343	vitamin D3 25-hydroxylase activity
0.43	GO:0034875	caffeine oxidase activity
0.43	GO:0070576	vitamin D 24-hydroxylase activity
0.40	GO:0005496	steroid binding
0.38	GO:0019899	enzyme binding
0.37	GO:0032451	demethylase activity

0.44	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.14.14	GO:0016712
0.35	KEGG:R07203	GO:0033777

sp|P05197|EF2_RAT
Elongation factor 2
Search

EEF2

0.56	Eukaryotic translation elongation factor 2

0.65	GO:0006414	translational elongation
0.50	GO:0002244	hematopoietic progenitor cell differentiation
0.48	GO:0045727	positive regulation of translation
0.40	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.40	GO:0051593	response to folic acid
0.40	GO:0014009	glial cell proliferation
0.40	GO:0002931	response to ischemia
0.40	GO:0003009	skeletal muscle contraction
0.39	GO:0032355	response to estradiol
0.39	GO:0035914	skeletal muscle cell differentiation

0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.64	GO:0003746	translation elongation factor activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0045296	cadherin binding
0.48	GO:0019901	protein kinase binding
0.39	GO:0002039	p53 binding
0.38	GO:0008097	5S rRNA binding

0.52	GO:0016235	aggresome
0.49	GO:0005844	polysome
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.38	GO:0045121	membrane raft
0.38	GO:0005634	nucleus
0.37	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen

sp|P05369|FPPS_RAT
Farnesyl pyrophosphate synthase
Search

FDPS

0.50	Farnesyl pyrophosphate synthetase

0.69	GO:0008299	isoprenoid biosynthetic process
0.49	GO:0045338	farnesyl diphosphate metabolic process
0.45	GO:0033383	geranyl diphosphate metabolic process
0.43	GO:0006695	cholesterol biosynthetic process
0.42	GO:0008654	phospholipid biosynthetic process
0.40	GO:0045540	regulation of cholesterol biosynthetic process
0.38	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development
0.37	GO:0090205	positive regulation of cholesterol metabolic process
0.37	GO:0033574	response to testosterone
0.37	GO:0070723	response to cholesterol

0.49	GO:0016740	transferase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0003723	RNA binding

0.44	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.36	GO:0005777	peroxisome
0.30	GO:0016021	integral component of membrane

0.49

EC:2

GO:0016740

sp|P05370|G6PD_RAT
Glucose-6-phosphate 1-dehydrogenase
Search

G6PD

0.42	Glucose-6-phosphate 1-dehydrogenase X

0.71	GO:0006098	pentose-phosphate shunt
0.71	GO:0006006	glucose metabolic process
0.56	GO:0019322	pentose biosynthetic process
0.56	GO:0010734	negative regulation of protein glutathionylation
0.54	GO:0043249	erythrocyte maturation
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0006695	cholesterol biosynthetic process
0.48	GO:0006749	glutathione metabolic process
0.47	GO:0034599	cellular response to oxidative stress
0.44	GO:0046390	ribose phosphate biosynthetic process

0.79	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.70	GO:0050661	NADP binding
0.50	GO:0005536	glucose binding
0.48	GO:0042803	protein homodimerization activity

0.48	GO:0009898	cytoplasmic side of plasma membrane
0.45	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.1.1.49

GO:0004345

sp|P05371|CLUS_RAT
Clusterin
Search

CLU

0.96

Clusterin

0.75	GO:1902847	regulation of neuronal signal transduction
0.75	GO:1905895	negative regulation of cellular response to tunicamycin
0.75	GO:1905892	negative regulation of cellular response to thapsigargin
0.75	GO:1902998	positive regulation of neurofibrillary tangle assembly
0.75	GO:0032463	negative regulation of protein homooligomerization
0.75	GO:0061518	microglial cell proliferation
0.74	GO:1902949	positive regulation of tau-protein kinase activity
0.74	GO:1905907	negative regulation of amyloid fibril formation
0.73	GO:0032286	central nervous system myelin maintenance
0.73	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.72	GO:0051787	misfolded protein binding
0.70	GO:0050750	low-density lipoprotein particle receptor binding
0.69	GO:0001540	amyloid-beta binding
0.66	GO:0031625	ubiquitin protein ligase binding
0.61	GO:0032403	protein complex binding
0.42	GO:0016887	ATPase activity
0.39	GO:0051087	chaperone binding
0.39	GO:0047485	protein N-terminus binding
0.37	GO:0097099	structural constituent of albumen

0.75	GO:0034366	spherical high-density lipoprotein particle
0.72	GO:0097418	neurofibrillary tangle
0.72	GO:0097440	apical dendrite
0.71	GO:0106003	amyloid-beta complex
0.66	GO:0048471	perinuclear region of cytoplasm
0.62	GO:0031012	extracellular matrix
0.61	GO:0009986	cell surface
0.55	GO:0042583	chromaffin granule
0.53	GO:0005739	mitochondrion
0.47	GO:0071944	cell periphery

0.42

GO:0016887

sp|P05426|RL7_RAT
60S ribosomal protein L7
Search

RPL7

0.64	Ribosomal protein L7

0.51	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.50	GO:0002181	cytoplasmic translation
0.38	GO:0051726	regulation of cell cycle
0.36	GO:0097421	liver regeneration
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0006413	translational initiation
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.44	GO:0003735	structural constituent of ribosome
0.43	GO:0003723	RNA binding
0.41	GO:0042803	protein homodimerization activity
0.36	GO:0003677	DNA binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity

0.60	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.48	GO:0005844	polysome
0.43	GO:0044446	intracellular organelle part
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.36	GO:0031672	A band
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

sp|P05432|ERRFI_RAT
ERBB receptor feedback inhibitor 1
Search

ERRFI1

0.97	ERBB receptor feedback inhibitor 1

0.81	GO:0060426	lung vasculature development
0.80	GO:0043589	skin morphogenesis
0.80	GO:0031953	negative regulation of protein autophosphorylation
0.80	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.79	GO:0045616	regulation of keratinocyte differentiation
0.78	GO:0060428	lung epithelium development
0.77	GO:0048286	lung alveolus development
0.54	GO:0018108	peptidyl-tyrosine phosphorylation
0.53	GO:0032966	negative regulation of collagen biosynthetic process
0.52	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress

0.70	GO:0019900	kinase binding
0.56	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.54	GO:0004713	protein tyrosine kinase activity
0.48	GO:0017124	SH3 domain binding
0.46	GO:0031267	small GTPase binding
0.44	GO:0005154	epidermal growth factor receptor binding
0.43	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.62	GO:0005829	cytosol
0.45	GO:0070436	Grb2-EGFR complex
0.43	GO:0005905	clathrin-coated pit
0.42	GO:0030136	clathrin-coated vesicle
0.42	GO:0005634	nucleus
0.37	GO:0005912	adherens junction
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0005768	endosome
0.35	GO:0030426	growth cone

0.56

EC:2.7.12.1

GO:0004712

sp|P05503|COX1_RAT
Cytochrome c oxidase subunit 1
Search

0.30	Cytochrome c oxidase subunit 1

0.64	GO:0006119	oxidative phosphorylation
0.64	GO:0009060	aerobic respiration
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.38	GO:0051602	response to electrical stimulus
0.37	GO:0021549	cerebellum development
0.37	GO:0046688	response to copper ion
0.37	GO:0007568	aging
0.35	GO:0006979	response to oxidative stress

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0020037	heme binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.63	GO:0005506	iron ion binding
0.62	GO:0009055	electron transfer activity

0.75	GO:0045277	respiratory chain complex IV
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.37	GO:0098798	mitochondrial protein complex
0.37	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P05504|ATP6_RAT
ATP synthase subunit a
Search

ATP6

0.42	ATP synthase subunit a

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0055093	response to hyperoxia
0.37	GO:0007568	aging

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0016887	ATPase activity

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.42	GO:0098798	mitochondrial protein complex
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.38

GO:0016887

sp|P05505|COX3_RAT
Cytochrome c oxidase subunit 3
Search

COX3

0.44	Cytochrome c oxidase subunit 3

0.76	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport
0.40	GO:0008535	respiratory chain complex IV assembly

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.39	GO:0045277	respiratory chain complex IV
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P05506|NU3M_RAT
NADH-ubiquinone oxidoreductase chain 3
Search

ND3

0.46	NADH-ubiquinone oxidoreductase chain 3

0.53	GO:0055114	oxidation-reduction process
0.37	GO:0071385	cellular response to glucocorticoid stimulus
0.37	GO:0009642	response to light intensity
0.35	GO:0006979	response to oxidative stress

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.59	GO:0070469	respiratory chain
0.59	GO:0031967	organelle envelope
0.58	GO:0031090	organelle membrane
0.40	GO:0030964	NADH dehydrogenase complex
0.38	GO:1990204	oxidoreductase complex
0.36	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P05507|NU4LM_RAT
NADH-ubiquinone oxidoreductase chain 4L
Search

ND4L

0.50	NADH-ubiquinone oxidoreductase chain 4L

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.38	GO:0070469	respiratory chain
0.38	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.36	GO:0030964	NADH dehydrogenase complex
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P05508|NU4M_RAT
NADH-ubiquinone oxidoreductase chain 4
Search

ND4

0.44	NADH-ubiquinone oxidoreductase chain 4

0.74	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.38	GO:0035094	response to nicotine
0.38	GO:0045471	response to ethanol
0.38	GO:0021549	cerebellum development
0.37	GO:0001666	response to hypoxia
0.37	GO:0001701	in utero embryonic development
0.37	GO:0007568	aging

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.41	GO:0045271	respiratory chain complex I
0.38	GO:1990204	oxidoreductase complex
0.37	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P05539|CO2A1_RAT
Collagen alpha-1(II) chain
Search

COL2A1

0.86	Collagen type II alpha 1 chain

0.64	GO:0060272	embryonic skeletal joint morphogenesis
0.63	GO:0060174	limb bud formation
0.62	GO:0001502	cartilage condensation
0.62	GO:0030199	collagen fibril organization
0.62	GO:0071599	otic vesicle development
0.62	GO:0001958	endochondral ossification
0.62	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.62	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.62	GO:0030903	notochord development
0.60	GO:0002062	chondrocyte differentiation

0.80	GO:0005201	extracellular matrix structural constituent
0.64	GO:0048407	platelet-derived growth factor binding
0.64	GO:0042289	MHC class II protein binding
0.54	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding

0.73	GO:0005581	collagen trimer
0.64	GO:0098643	banded collagen fibril
0.58	GO:0005604	basement membrane
0.54	GO:0005615	extracellular space
0.40	GO:0005737	cytoplasm
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P05540|CD4_RAT
T-cell surface glycoprotein CD4
Search

CD4

0.91	T-cell surface glycoprotein CD4

0.73	GO:0006955	immune response
0.72	GO:0007155	cell adhesion
0.60	GO:0007165	signal transduction
0.59	GO:0045058	T cell selection
0.58	GO:0006948	induction by virus of host cell-cell fusion
0.57	GO:0071350	cellular response to interleukin-15
0.56	GO:0046598	positive regulation of viral entry into host cell
0.56	GO:0045657	positive regulation of monocyte differentiation
0.56	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.54	GO:0035397	helper T cell enhancement of adaptive immune response

0.85	GO:0015026	coreceptor activity
0.58	GO:0042012	interleukin-16 receptor activity
0.58	GO:0042011	interleukin-16 binding
0.56	GO:0042289	MHC class II protein binding
0.54	GO:1990782	protein tyrosine kinase binding
0.49	GO:0042803	protein homodimerization activity
0.44	GO:0008270	zinc ion binding
0.39	GO:0019865	immunoglobulin binding
0.36	GO:0001618	virus receptor activity
0.35	GO:0005201	extracellular matrix structural constituent

0.52	GO:0009897	external side of plasma membrane
0.51	GO:0098857	membrane microdomain
0.49	GO:0005788	endoplasmic reticulum lumen
0.46	GO:0005887	integral component of plasma membrane
0.45	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0042101	T cell receptor complex
0.35	GO:0030665	clathrin-coated vesicle membrane
0.35	GO:0005769	early endosome

sp|P05541|CD8B_RAT
T-cell surface glycoprotein CD8 beta chain
Search

CD8B

0.93	T-cell surface glycoprotein CD8 beta chain

0.50

GO:0002250

adaptive immune response

0.37

GO:0005515

protein binding

0.52	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P05544|SPA3L_RAT
Serine protease inhibitor A3L
Search

0.73	Serine protease inhibitor

0.55	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0043434	response to peptide hormone
0.42	GO:0034097	response to cytokine
0.39	GO:0008211	glucocorticoid metabolic process
0.38	GO:0006954	inflammatory response
0.37	GO:0006508	proteolysis
0.36	GO:0006955	immune response
0.36	GO:0034516	response to vitamin B6
0.36	GO:0001937	negative regulation of endothelial cell proliferation
0.36	GO:0016525	negative regulation of angiogenesis

0.57	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0005496	steroid binding
0.37	GO:0008233	peptidase activity
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.43	GO:0042583	chromaffin granule
0.37	GO:1903561	extracellular vesicle
0.35	GO:0031093	platelet alpha granule lumen
0.35	GO:0035578	azurophil granule lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0008233

sp|P05545|SPA3K_RAT
Serine protease inhibitor A3K
Search

0.73	Serine protease inhibitor

0.56	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0043434	response to peptide hormone
0.42	GO:0034097	response to cytokine
0.39	GO:0006954	inflammatory response
0.38	GO:0006508	proteolysis
0.37	GO:0006955	immune response
0.36	GO:0001937	negative regulation of endothelial cell proliferation
0.36	GO:0019216	regulation of lipid metabolic process
0.36	GO:0034516	response to vitamin B6
0.36	GO:0016525	negative regulation of angiogenesis

0.57	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0008233	peptidase activity
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.34	GO:0005515	protein binding
0.34	GO:0005496	steroid binding
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.44	GO:0042583	chromaffin granule
0.37	GO:1903561	extracellular vesicle
0.35	GO:0031093	platelet alpha granule lumen
0.35	GO:0035578	azurophil granule lumen
0.34	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0008233

sp|P05554|CEBPA_RAT
CCAAT/enhancer-binding protein alpha
Search

CEBPA

0.88	CCAAT/enhancer-binding protein alpha

0.62	GO:0030851	granulocyte differentiation
0.60	GO:0030225	macrophage differentiation
0.59	GO:0001889	liver development
0.57	GO:0045600	positive regulation of fat cell differentiation
0.57	GO:0045669	positive regulation of osteoblast differentiation
0.57	GO:0045444	fat cell differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0071285	cellular response to lithium ion

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0000987	proximal promoter sequence-specific DNA binding
0.53	GO:0019900	kinase binding
0.53	GO:0042803	protein homodimerization activity
0.51	GO:0003713	transcription coactivator activity
0.48	GO:0008134	transcription factor binding
0.45	GO:0042826	histone deacetylase binding
0.44	GO:0035035	histone acetyltransferase binding
0.44	GO:0001046	core promoter sequence-specific DNA binding

0.52	GO:0005654	nucleoplasm
0.50	GO:0090575	RNA polymerase II transcription factor complex
0.45	GO:0016363	nuclear matrix
0.42	GO:0000779	condensed chromosome, centromeric region
0.41	GO:0000790	nuclear chromatin
0.40	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane

sp|P05696|KPCA_RAT
Protein kinase C alpha type
Search

PRKCA

0.76	Protein kinase C alpha type

0.64	GO:0035408	histone H3-T6 phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.59	GO:0045766	positive regulation of angiogenesis
0.59	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.59	GO:0034351	negative regulation of glial cell apoptotic process
0.58	GO:0090330	regulation of platelet aggregation
0.57	GO:0002159	desmosome assembly
0.56	GO:0001938	positive regulation of endothelial cell proliferation
0.56	GO:0010595	positive regulation of endothelial cell migration
0.55	GO:0043535	regulation of blood vessel endothelial cell migration

0.82	GO:0004697	protein kinase C activity
0.64	GO:0035403	histone kinase activity (H3-T6 specific)
0.62	GO:0008270	zinc ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0019899	enzyme binding
0.47	GO:0050681	androgen receptor binding
0.46	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

0.51	GO:0005829	cytosol
0.49	GO:0005886	plasma membrane
0.48	GO:0005783	endoplasmic reticulum
0.41	GO:0005654	nucleoplasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0070062	extracellular exosome
0.38	GO:0001750	photoreceptor outer segment
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.36	GO:0045177	apical part of cell

0.82

GO:0004697

sp|P05708|HXK1_RAT
Hexokinase-1
Search

HK1

0.34	Phosphotransferase

0.82	GO:0001678	cellular glucose homeostasis
0.74	GO:0046835	carbohydrate phosphorylation
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.49	GO:0051156	glucose 6-phosphate metabolic process
0.48	GO:0072656	maintenance of protein location in mitochondrion
0.48	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.48	GO:0050718	positive regulation of interleukin-1 beta secretion

0.83	GO:0005536	glucose binding
0.79	GO:0004396	hexokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042834	peptidoglycan binding
0.30	GO:0042803	protein homodimerization activity
0.30	GO:0032403	protein complex binding
0.30	GO:0016887	ATPase activity
0.30	GO:0004672	protein kinase activity

0.48	GO:0005829	cytosol
0.47	GO:0097228	sperm principal piece
0.45	GO:0045121	membrane raft
0.39	GO:0005739	mitochondrion
0.30	GO:0032991	macromolecular complex
0.30	GO:0044459	plasma membrane part
0.30	GO:0098588	bounding membrane of organelle
0.30	GO:0031975	envelope
0.30	GO:0044446	intracellular organelle part
0.30	GO:0019867	outer membrane

0.79

EC:2.7.1.1

GO:0004396

sp|P05710|PRLR_RAT
Prolactin receptor
Search

PRLR

0.65	Prolactin receptor long form

0.84	GO:0038161	prolactin signaling pathway
0.61	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.53	GO:0007595	lactation
0.53	GO:0060736	prostate gland growth
0.53	GO:0060644	mammary gland epithelial cell differentiation
0.52	GO:0061377	mammary gland lobule development
0.51	GO:0007259	JAK-STAT cascade
0.50	GO:0030856	regulation of epithelial cell differentiation
0.47	GO:0030155	regulation of cell adhesion
0.40	GO:0042976	activation of Janus kinase activity

0.85	GO:0004925	prolactin receptor activity
0.59	GO:0017046	peptide hormone binding
0.38	GO:0005515	protein binding
0.37	GO:0046872	metal ion binding
0.37	GO:0042978	ornithine decarboxylase activator activity

0.53	GO:0009986	cell surface
0.37	GO:0031904	endosome lumen
0.36	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P05712|RAB2A_RAT
Ras-related protein Rab-2A
Search

RAB2A

0.93	RAS oncogene family member RAB2

0.62

GO:0007030

Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58

GO:0005794

Golgi apparatus

sp|P05714|RAB4A_RAT
Ras-related protein Rab-4A
Search

RAB4A

0.97	RAB4A, member RAS oncogene family variant (Fragment)

0.61	GO:0030100	regulation of endocytosis
0.55	GO:0019882	antigen processing and presentation
0.49	GO:0015031	protein transport
0.48	GO:0001944	vasculature development
0.38	GO:0032482	Rab protein signal transduction
0.37	GO:0032781	positive regulation of ATPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008565	protein transporter activity
0.38	GO:0035255	ionotropic glutamate receptor binding
0.37	GO:0051117	ATPase binding
0.37	GO:0019905	syntaxin binding
0.37	GO:0001671	ATPase activator activity

0.58	GO:0070062	extracellular exosome
0.57	GO:0005768	endosome
0.57	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0032593	insulin-responsive compartment
0.36	GO:0098794	postsynapse
0.35	GO:0005829	cytosol
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P05765|RS21_RAT
40S ribosomal protein S21
Search

RPS21

0.71	Ribosomal protein S21

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.45	GO:0042274	ribosomal small subunit biogenesis
0.44	GO:0016072	rRNA metabolic process
0.44	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.37	GO:0048542	lymph gland development
0.36	GO:0006417	regulation of translation
0.36	GO:0042127	regulation of cell proliferation

0.63	GO:0003735	structural constituent of ribosome
0.52	GO:0047485	protein N-terminus binding
0.38	GO:0043022	ribosome binding
0.34	GO:0003723	RNA binding

0.60	GO:0005840	ribosome
0.53	GO:0005844	polysome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

sp|P05942|S10A4_RAT
Protein S100-A4
Search

sp|P05943|S10AA_RAT
Protein S100-A10
Search

S100A10

0.97	S100 calcium binding protein A10

0.56	GO:0051894	positive regulation of focal adhesion assembly
0.56	GO:0051290	protein heterotetramerization
0.56	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.55	GO:0051496	positive regulation of stress fiber assembly
0.55	GO:0001765	membrane raft assembly
0.53	GO:0072659	protein localization to plasma membrane
0.53	GO:0006900	vesicle budding from membrane
0.52	GO:0051099	positive regulation of binding
0.50	GO:0043547	positive regulation of GTPase activity
0.46	GO:0042127	regulation of cell proliferation

0.68	GO:0005509	calcium ion binding
0.54	GO:0044325	ion channel binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0048306	calcium-dependent protein binding
0.36	GO:0008289	lipid binding
0.32	GO:0046914	transition metal ion binding

0.52	GO:0045121	membrane raft
0.49	GO:0019897	extrinsic component of plasma membrane
0.46	GO:0005576	extracellular region
0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0031982	vesicle
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P05964|S10A6_RAT
Protein S100-A6
Search

0.86	S100 calcium binding protein A6

0.49	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.45	GO:0008016	regulation of heart contraction
0.36	GO:0051000	positive regulation of nitric-oxide synthase activity
0.36	GO:0043542	endothelial cell migration
0.36	GO:1903672	positive regulation of sprouting angiogenesis
0.34	GO:0048168	regulation of neuronal synaptic plasticity
0.34	GO:0007613	memory
0.33	GO:0034220	ion transmembrane transport

0.68	GO:0005509	calcium ion binding
0.55	GO:0042802	identical protein binding
0.55	GO:0044548	S100 protein binding
0.54	GO:0048306	calcium-dependent protein binding
0.53	GO:0005523	tropomyosin binding
0.51	GO:0050786	RAGE receptor binding
0.51	GO:0046914	transition metal ion binding
0.47	GO:0046983	protein dimerization activity
0.38	GO:0019899	enzyme binding
0.33	GO:0003779	actin binding

0.57	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0001726	ruffle
0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.50	GO:0005576	extracellular region
0.49	GO:0005635	nuclear envelope
0.47	GO:0005829	cytosol
0.36	GO:0097458	neuron part
0.36	GO:0044297	cell body
0.35	GO:0016529	sarcoplasmic reticulum

sp|P05982|NQO1_RAT
NAD(P)H dehydrogenase [quinone] 1
Search

NQO1

0.96	NAD(P)H quinone oxidoreductase 1

0.70	GO:0043086	negative regulation of catalytic activity
0.68	GO:0006979	response to oxidative stress
0.55	GO:1904880	response to hydrogen sulfide
0.53	GO:0051602	response to electrical stimulus
0.52	GO:0043525	positive regulation of neuron apoptotic process
0.51	GO:0032355	response to estradiol
0.51	GO:0055114	oxidation-reduction process
0.51	GO:0045471	response to ethanol
0.50	GO:0071248	cellular response to metal ion
0.50	GO:0007584	response to nutrient

0.78	GO:0003955	NAD(P)H dehydrogenase (quinone) activity
0.71	GO:0042802	identical protein binding
0.48	GO:0004784	superoxide dismutase activity
0.43	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
0.38	GO:0003723	RNA binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0005829	cytosol
0.49	GO:0043025	neuronal cell body
0.49	GO:0030425	dendrite
0.44	GO:0070062	extracellular exosome

0.78

EC:1.6.5.2

GO:0003955

sp|P06211|ESR1_RAT
Estrogen receptor
Search

ESR1

0.94	Estrogen receptor

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0060523	prostate epithelial cord elongation
0.60	GO:0071392	cellular response to estradiol stimulus
0.59	GO:0001547	antral ovarian follicle growth
0.59	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA
0.59	GO:0060526	prostate glandular acinus morphogenesis
0.59	GO:0060687	regulation of branching involved in prostate gland morphogenesis
0.58	GO:0060068	vagina development
0.58	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0006351	transcription, DNA-templated

0.85	GO:0030284	estrogen receptor activity
0.81	GO:0005496	steroid binding
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001093	TFIIB-class transcription factor binding
0.58	GO:0001223	transcription coactivator binding
0.58	GO:0030331	estrogen receptor binding
0.57	GO:0051117	ATPase binding
0.55	GO:0008013	beta-catenin binding

0.61	GO:0005634	nucleus
0.58	GO:0097550	transcriptional preinitiation complex
0.56	GO:0035327	transcriptionally active chromatin
0.48	GO:0070013	intracellular organelle lumen
0.44	GO:0043234	protein complex
0.43	GO:0005886	plasma membrane
0.40	GO:0005794	Golgi apparatus
0.35	GO:0043204	perikaryon
0.35	GO:0043195	terminal bouton
0.35	GO:0048471	perinuclear region of cytoplasm

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P06214|HEM2_RAT
Delta-aminolevulinic acid dehydratase
Search

ALAD

0.49	Delta-aminolevulinic acid dehydratase

0.69	GO:0006779	porphyrin-containing compound biosynthetic process
0.57	GO:0071353	cellular response to interleukin-4
0.56	GO:1901799	negative regulation of proteasomal protein catabolic process
0.52	GO:0051260	protein homooligomerization
0.52	GO:0042168	heme metabolic process
0.51	GO:0046148	pigment biosynthetic process
0.42	GO:0070541	response to platinum ion
0.41	GO:0071284	cellular response to lead ion
0.41	GO:0010266	response to vitamin B1
0.41	GO:0033197	response to vitamin E

0.80	GO:0004655	porphobilinogen synthase activity
0.54	GO:0046872	metal ion binding
0.50	GO:0042802	identical protein binding
0.41	GO:1904854	proteasome core complex binding

0.43	GO:0005829	cytosol
0.38	GO:0005839	proteasome core complex
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80	EC:4.2.1.24	GO:0004655
0.80	KEGG:R00036	GO:0004655

sp|P06238|A2MG_RAT
Alpha-2-macroglobulin
Search

A2M

0.63	Alpha-macroglobulin

0.75	GO:0010951	negative regulation of endopeptidase activity
0.55	GO:0001869	negative regulation of complement activation, lectin pathway
0.43	GO:0007565	female pregnancy
0.42	GO:0048863	stem cell differentiation
0.39	GO:0007275	multicellular organism development
0.38	GO:0006953	acute-phase response
0.37	GO:0009611	response to wounding
0.37	GO:0002438	acute inflammatory response to antigenic stimulus
0.37	GO:0010037	response to carbon dioxide
0.37	GO:0034695	response to prostaglandin E

0.76	GO:0004866	endopeptidase inhibitor activity
0.55	GO:0043120	tumor necrosis factor binding
0.54	GO:0019959	interleukin-8 binding
0.53	GO:0019966	interleukin-1 binding
0.51	GO:0048306	calcium-dependent protein binding
0.51	GO:0002020	protease binding
0.46	GO:0005102	receptor binding
0.39	GO:0048403	brain-derived neurotrophic factor binding
0.38	GO:0048406	nerve growth factor binding
0.35	GO:0042803	protein homodimerization activity

0.73	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.36	GO:0031093	platelet alpha granule lumen
0.34	GO:0005829	cytosol
0.32	GO:0019866	organelle inner membrane
0.32	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P06300|PDYN_RAT
Proenkephalin-B
Search

PDYN

0.97	Beta-neoendorphin-dynorphin

0.80	GO:0007218	neuropeptide signaling pathway
0.64	GO:0010469	regulation of receptor activity
0.50	GO:0098916	anterograde trans-synaptic signaling
0.48	GO:0007600	sensory perception
0.39	GO:0046928	regulation of neurotransmitter secretion

0.74	GO:0001515	opioid peptide activity
0.56	GO:0031628	opioid receptor binding
0.52	GO:0005184	neuropeptide hormone activity

0.56	GO:0005576	extracellular region
0.52	GO:0043679	axon terminus
0.51	GO:0043025	neuronal cell body
0.51	GO:0030425	dendrite
0.46	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm

sp|P06302|PTMA_RAT
Prothymosin alpha
Search

PTMA

0.96	Prothymosin alpha

0.62	GO:0043486	histone exchange
0.42	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.42	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.41	GO:0008283	cell proliferation
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0030154	cell differentiation
0.38	GO:0016024	CDP-diacylglycerol biosynthetic process
0.38	GO:0032049	cardiolipin biosynthetic process
0.36	GO:0006351	transcription, DNA-templated

0.66	GO:0033613	activating transcription factor binding
0.59	GO:0042393	histone binding
0.39	GO:0035091	phosphatidylinositol binding
0.38	GO:0004605	phosphatidate cytidylyltransferase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003676	nucleic acid binding

0.59	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol
0.45	GO:0070062	extracellular exosome
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

0.38

EC:2.7.7.41

GO:0004605

sp|P06303|PAHO_RAT
Pancreatic prohormone
Search

PPY

0.97	Pancreatic prohormone precursor

0.76	GO:0010469	regulation of receptor activity
0.60	GO:0032098	regulation of appetite
0.58	GO:0007631	feeding behavior
0.58	GO:0007586	digestion
0.56	GO:0007218	neuropeptide signaling pathway
0.53	GO:0007267	cell-cell signaling
0.37	GO:0009306	protein secretion

0.79	GO:0005179	hormone activity
0.66	GO:0001664	G-protein coupled receptor binding

0.66	GO:0005576	extracellular region
0.42	GO:0005737	cytoplasm

sp|P06341|HB2A_RAT
Rano class II histocompatibility antigen, A beta chain (Fragment)
Search

HLA-DQB1

0.43	Major histocompatibility complex class II antigen DQB

0.82	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.40	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.39	GO:0002343	peripheral B cell selection
0.39	GO:0002579	positive regulation of antigen processing and presentation
0.39	GO:0002827	positive regulation of T-helper 1 type immune response
0.38	GO:0046635	positive regulation of alpha-beta T cell activation
0.38	GO:0002377	immunoglobulin production
0.38	GO:0002449	lymphocyte mediated immunity
0.37	GO:0071345	cellular response to cytokine stimulus

0.40	GO:0042605	peptide antigen binding
0.39	GO:1990405	protein antigen binding
0.38	GO:0015643	toxic substance binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0008134	transcription factor binding
0.34	GO:0046982	protein heterodimerization activity

0.75	GO:0042613	MHC class II protein complex
0.38	GO:0005771	multivesicular body
0.38	GO:0009986	cell surface
0.37	GO:0005769	early endosome
0.36	GO:0098552	side of membrane
0.36	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|P06349|H1T_RAT
Histone H1t
Search

0.97	Testicular H1 histone

0.79	GO:0006334	nucleosome assembly
0.53	GO:0098532	histone H3-K27 trimethylation
0.51	GO:0080182	histone H3-K4 trimethylation
0.51	GO:0016584	nucleosome positioning
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0007283	spermatogenesis
0.44	GO:0048260	positive regulation of receptor-mediated endocytosis
0.39	GO:0030154	cell differentiation
0.39	GO:0007339	binding of sperm to zona pellucida
0.38	GO:0030317	flagellated sperm motility

0.60	GO:0031490	chromatin DNA binding
0.43	GO:0008201	heparin binding
0.40	GO:0032564	dATP binding
0.39	GO:0003690	double-stranded DNA binding
0.37	GO:0005515	protein binding
0.37	GO:0016208	AMP binding
0.37	GO:0043531	ADP binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.56	GO:0000791	euchromatin
0.52	GO:0031974	membrane-enclosed lumen
0.46	GO:0000792	heterochromatin
0.45	GO:0035327	transcriptionally active chromatin
0.41	GO:0009986	cell surface
0.41	GO:0031982	vesicle
0.37	GO:0000793	condensed chromosome
0.35	GO:0043230	extracellular organelle

sp|P06399|FIBA_RAT
Fibrinogen alpha chain
Search

FGA

0.70	Fibrinogen alpha chain

0.82	GO:0007596	blood coagulation
0.74	GO:0001775	cell activation
0.72	GO:0051258	protein polymerization
0.61	GO:0043152	induction of bacterial agglutination
0.60	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.60	GO:0042730	fibrinolysis
0.59	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.59	GO:0045907	positive regulation of vasoconstriction
0.59	GO:2000352	negative regulation of endothelial cell apoptotic process
0.59	GO:0031639	plasminogen activation

0.74	GO:0030674	protein binding, bridging
0.68	GO:0005102	receptor binding
0.55	GO:0050839	cell adhesion molecule binding
0.46	GO:0005198	structural molecule activity
0.36	GO:0046872	metal ion binding

0.81	GO:0005577	fibrinogen complex
0.59	GO:0031091	platelet alpha granule
0.56	GO:0009897	external side of plasma membrane
0.53	GO:0005938	cell cortex
0.40	GO:0072562	blood microparticle
0.39	GO:0070062	extracellular exosome
0.39	GO:0005791	rough endoplasmic reticulum
0.32	GO:0034774	secretory granule lumen
0.32	GO:0005788	endoplasmic reticulum lumen

sp|P06494|ERBB2_RAT
Receptor tyrosine-protein kinase erbB-2
Search

ERBB2

0.67	Receptor protein-tyrosine kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.75	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.64	GO:0033088	negative regulation of immature T cell proliferation in thymus
0.63	GO:0023014	signal transduction by protein phosphorylation
0.63	GO:0090314	positive regulation of protein targeting to membrane
0.62	GO:0045945	positive regulation of transcription by RNA polymerase III
0.62	GO:0071364	cellular response to epidermal growth factor stimulus
0.61	GO:0045943	positive regulation of transcription by RNA polymerase I
0.60	GO:0008045	motor neuron axon guidance
0.60	GO:0014065	phosphatidylinositol 3-kinase signaling

0.82	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.79	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.64	GO:0001042	RNA polymerase I core binding
0.58	GO:0019903	protein phosphatase binding
0.58	GO:0008022	protein C-terminus binding
0.58	GO:0019838	growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0046982	protein heterodimerization activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0043209	myelin sheath
0.58	GO:0016323	basolateral plasma membrane
0.58	GO:0016324	apical plasma membrane
0.56	GO:0043235	receptor complex
0.56	GO:0010008	endosome membrane
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.42	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0045178	basal part of cell
0.37	GO:0005902	microvillus

0.82	EC:2.7.10	GO:0004716
0.37	KEGG:R04545	GO:0046934

sp|P06536|GCR_RAT
Glucocorticoid receptor
Search

NR3C1

0.87	Glucocorticoid receptor variant gamma

0.86	GO:0043402	glucocorticoid mediated signaling pathway
0.85	GO:0042921	glucocorticoid receptor signaling pathway
0.60	GO:0071549	cellular response to dexamethasone stimulus
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0071560	cellular response to transforming growth factor beta stimulus
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.54	GO:0010467	gene expression

0.86	GO:0004883	glucocorticoid receptor activity
0.81	GO:0005496	steroid binding
0.66	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0042562	hormone binding
0.59	GO:0032183	SUMO binding
0.59	GO:0051879	Hsp90 protein binding
0.56	GO:0001047	core promoter binding

0.61	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.50	GO:0005829	cytosol
0.45	GO:0044446	intracellular organelle part
0.45	GO:0043234	protein complex
0.43	GO:0015630	microtubule cytoskeleton
0.40	GO:0005739	mitochondrion
0.35	GO:0043197	dendritic spine
0.35	GO:0014069	postsynaptic density
0.30	GO:0016020	membrane

sp|P06685|AT1A1_RAT
Sodium/potassium-transporting ATPase subunit alpha-1
Search

ATP1A1

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.54	GO:1903416	response to glycoside
0.53	GO:0006883	cellular sodium ion homeostasis
0.53	GO:0086009	membrane repolarization
0.53	GO:0031947	negative regulation of glucocorticoid biosynthetic process
0.52	GO:0045989	positive regulation of striated muscle contraction
0.52	GO:0045822	negative regulation of heart contraction

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0046872	metal ion binding
0.53	GO:1990239	steroid hormone binding
0.47	GO:0051087	chaperone binding
0.44	GO:0016791	phosphatase activity
0.38	GO:0030506	ankyrin binding

0.53	GO:0042383	sarcolemma
0.51	GO:0005890	sodium:potassium-exchanging ATPase complex
0.49	GO:0014069	postsynaptic density
0.49	GO:0043209	myelin sheath
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0016324	apical plasma membrane
0.41	GO:0043234	protein complex
0.38	GO:0014704	intercalated disc
0.37	GO:0005901	caveola
0.37	GO:0031410	cytoplasmic vesicle

0.85

GO:0005391

sp|P06686|AT1A2_RAT
Sodium/potassium-transporting ATPase subunit alpha-2
Search

ATP1A2

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.60	GO:0006883	cellular sodium ion homeostasis
0.58	GO:0008542	visual learning
0.57	GO:0030007	cellular potassium ion homeostasis
0.57	GO:0140115	export across plasma membrane
0.57	GO:0008344	adult locomotory behavior
0.56	GO:0008015	blood circulation

0.84	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:1990239	steroid hormone binding
0.53	GO:0046872	metal ion binding
0.53	GO:0051087	chaperone binding
0.48	GO:0001540	amyloid-beta binding
0.44	GO:1901681	sulfur compound binding

0.57	GO:0005890	sodium:potassium-exchanging ATPase complex
0.57	GO:0042383	sarcolemma
0.56	GO:0043209	myelin sheath
0.48	GO:0036477	somatodendritic compartment
0.47	GO:0043005	neuron projection
0.46	GO:0044297	cell body
0.44	GO:0012505	endomembrane system
0.42	GO:0098794	postsynapse
0.41	GO:0005634	nucleus
0.41	GO:0098590	plasma membrane region

0.84

GO:0005391

sp|P06687|AT1A3_RAT
Sodium/potassium-transporting ATPase subunit alpha-3
Search

ATP1A3

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.76	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.56	GO:0006883	cellular sodium ion homeostasis
0.55	GO:0007626	locomotory behavior
0.54	GO:0008542	visual learning
0.53	GO:0030007	cellular potassium ion homeostasis
0.53	GO:0140115	export across plasma membrane
0.53	GO:0086036	regulation of cardiac muscle cell membrane potential

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.50	GO:0051087	chaperone binding
0.50	GO:0001540	amyloid-beta binding
0.46	GO:1990239	steroid hormone binding
0.45	GO:1901681	sulfur compound binding

0.54	GO:0005890	sodium:potassium-exchanging ATPase complex
0.54	GO:0042383	sarcolemma
0.53	GO:0043209	myelin sheath
0.48	GO:0036477	somatodendritic compartment
0.48	GO:0044297	cell body
0.48	GO:0043005	neuron projection
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.42	GO:0098794	postsynapse
0.42	GO:0005634	nucleus

0.85

GO:0005391

sp|P06757|ADH1_RAT
Alcohol dehydrogenase 1
Search

0.39	Alcohol dehydrogenase E chain

0.51	GO:0055114	oxidation-reduction process
0.45	GO:0006067	ethanol metabolic process
0.41	GO:0001523	retinoid metabolic process
0.41	GO:0045471	response to ethanol
0.41	GO:0033574	response to testosterone
0.41	GO:0032526	response to retinoic acid
0.40	GO:0034310	primary alcohol catabolic process
0.40	GO:0030534	adult behavior
0.39	GO:0034754	cellular hormone metabolic process
0.39	GO:0048545	response to steroid hormone

0.61	GO:0008270	zinc ion binding
0.56	GO:0004022	alcohol dehydrogenase (NAD) activity
0.41	GO:0004745	retinol dehydrogenase activity
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0035276	ethanol binding
0.35	GO:0004031	aldehyde oxidase activity
0.35	GO:0019841	retinol binding
0.35	GO:0048019	receptor antagonist activity
0.34	GO:0051287	NAD binding

0.43	GO:0005829	cytosol
0.43	GO:0005654	nucleoplasm
0.39	GO:0005886	plasma membrane
0.36	GO:0005739	mitochondrion
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.56

EC:1.1.1.1

GO:0004022

sp|P06759|APOC3_RAT
Apolipoprotein C-III
Search

APOC3

0.96	Apolipoprotein C-III

0.82	GO:0010987	negative regulation of high-density lipoprotein particle clearance
0.81	GO:0010897	negative regulation of triglyceride catabolic process
0.80	GO:0010989	negative regulation of low-density lipoprotein particle clearance
0.80	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.79	GO:0051005	negative regulation of lipoprotein lipase activity
0.78	GO:0060621	negative regulation of cholesterol import
0.77	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
0.76	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.76	GO:0019433	triglyceride catabolic process
0.76	GO:0071827	plasma lipoprotein particle organization

0.80	GO:0070653	high-density lipoprotein particle receptor binding
0.75	GO:0055102	lipase inhibitor activity
0.72	GO:0008289	lipid binding
0.48	GO:0043168	anion binding
0.45	GO:0005319	lipid transporter activity

0.79	GO:0034363	intermediate-density lipoprotein particle
0.78	GO:0034366	spherical high-density lipoprotein particle
0.76	GO:0042627	chylomicron
0.75	GO:0034361	very-low-density lipoprotein particle
0.63	GO:0031012	extracellular matrix
0.46	GO:0070062	extracellular exosome
0.41	GO:0005829	cytosol

sp|P06760|BGLR_RAT
Beta-glucuronidase
Search

GUSB

0.51	Beta-glucuronidase

0.60	GO:0005975	carbohydrate metabolic process
0.36	GO:0046677	response to antibiotic
0.36	GO:0006027	glycosaminoglycan catabolic process
0.35	GO:0006907	pinocytosis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008333	endosome to lysosome transport
0.35	GO:0030212	hyaluronan metabolic process
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0046395	carboxylic acid catabolic process

0.81	GO:0004566	beta-glucuronidase activity
0.51	GO:0019904	protein domain specific binding
0.49	GO:0005102	receptor binding
0.34	GO:0030246	carbohydrate binding

0.74	GO:0005764	lysosome
0.49	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:0009986	cell surface
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.81

EC:3.2.1.31

GO:0004566

sp|P06761|GRP78_RAT
78 kDa glucose-regulated protein
Search

HSPA5

0.73	Glucose-regulated protein 78

0.54	GO:1903895	negative regulation of IRE1-mediated unfolded protein response
0.53	GO:0090074	negative regulation of protein homodimerization activity
0.50	GO:0035437	maintenance of protein localization in endoplasmic reticulum
0.49	GO:0030335	positive regulation of cell migration
0.49	GO:0021589	cerebellum structural organization
0.48	GO:0006987	activation of signaling protein activity involved in unfolded protein response
0.47	GO:0006983	ER overload response
0.47	GO:0071353	cellular response to interleukin-4
0.46	GO:0021680	cerebellar Purkinje cell layer development
0.46	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0051787	misfolded protein binding
0.45	GO:0045296	cadherin binding
0.44	GO:0019904	protein domain specific binding
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0016887	ATPase activity
0.43	GO:0043022	ribosome binding

0.53	GO:0005788	endoplasmic reticulum lumen
0.48	GO:0042470	melanosome
0.47	GO:0034663	endoplasmic reticulum chaperone complex
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.45	GO:0030496	midbody
0.45	GO:0043209	myelin sheath
0.45	GO:0030176	integral component of endoplasmic reticulum membrane
0.45	GO:0008180	COP9 signalosome
0.43	GO:0009986	cell surface
0.42	GO:0005790	smooth endoplasmic reticulum

0.43

GO:0016887

sp|P06762|HMOX1_RAT
Heme oxygenase 1
Search

HMOX1

0.58	Heme oxygenase

0.81	GO:0006788	heme oxidation
0.60	GO:0042167	heme catabolic process
0.59	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron
0.59	GO:0072719	cellular response to cisplatin
0.59	GO:0002246	wound healing involved in inflammatory response
0.58	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.58	GO:0071243	cellular response to arsenic-containing substance
0.57	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.57	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.57	GO:0048662	negative regulation of smooth muscle cell proliferation

0.81	GO:0004392	heme oxygenase (decyclizing) activity
0.51	GO:0042803	protein homodimerization activity
0.47	GO:0020037	heme binding
0.47	GO:0046872	metal ion binding
0.41	GO:0004630	phospholipase D activity
0.38	GO:0019899	enzyme binding
0.35	GO:0004871	signal transducer activity

0.53	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005783	endoplasmic reticulum
0.45	GO:0005634	nucleus
0.41	GO:0005901	caveola
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.38	GO:0005829	cytosol
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0035579	specific granule membrane

0.81

EC:1.14.99.3

GO:0004392

sp|P06765|PLF4_RAT
Platelet factor 4
Search

0.77	C-X-C motif chemokine

0.83	GO:0030168	platelet activation
0.83	GO:0030595	leukocyte chemotaxis
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.72	GO:0006952	defense response
0.59	GO:0001562	response to protozoan
0.52	GO:0019221	cytokine-mediated signaling pathway
0.52	GO:0045347	negative regulation of MHC class II biosynthetic process
0.51	GO:0045653	negative regulation of megakaryocyte differentiation
0.51	GO:0045918	negative regulation of cytolysis

0.84	GO:0008009	chemokine activity
0.81	GO:0008201	heparin binding
0.56	GO:0045236	CXCR chemokine receptor binding

0.73	GO:0005615	extracellular space
0.52	GO:0097679	other organism cytoplasm
0.51	GO:0020005	symbiont-containing vacuole membrane
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P06766|DPOLB_RAT
DNA polymerase beta
Search

POLB

0.90	LOW QUALITY PROTEIN: DNA polymerase beta

0.65	GO:0071897	DNA biosynthetic process
0.63	GO:0006281	DNA repair
0.58	GO:0071707	immunoglobulin heavy chain V-D-J recombination
0.56	GO:0016446	somatic hypermutation of immunoglobulin genes
0.55	GO:0048535	lymph node development
0.55	GO:0048536	spleen development
0.54	GO:0051402	neuron apoptotic process
0.54	GO:0007435	salivary gland morphogenesis
0.54	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.51	GO:0006954	inflammatory response

0.68	GO:0003887	DNA-directed DNA polymerase activity
0.53	GO:0003677	DNA binding
0.51	GO:0008017	microtubule binding
0.49	GO:0019899	enzyme binding
0.45	GO:0016829	lyase activity
0.35	GO:0046872	metal ion binding

0.59	GO:0005634	nucleus
0.54	GO:0005876	spindle microtubule
0.44	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0000793	condensed chromosome
0.34	GO:0044427	chromosomal part
0.30	GO:0016021	integral component of membrane

0.68

GO:0003887

sp|P06767|TKN1_RAT
Protachykinin-1
Search

0.73	Tachykinin precursor 1

0.85	GO:0007217	tachykinin receptor signaling pathway
0.50	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.49	GO:0006954	inflammatory response
0.49	GO:1990090	cellular response to nerve growth factor stimulus
0.48	GO:0048265	response to pain
0.48	GO:0019233	sensory perception of pain
0.43	GO:0007267	cell-cell signaling
0.43	GO:0007218	neuropeptide signaling pathway
0.30	GO:0050671	positive regulation of lymphocyte proliferation
0.30	GO:0051272	positive regulation of cellular component movement

0.41

GO:0005102

receptor binding

0.46	GO:0005576	extracellular region
0.46	GO:0043025	neuronal cell body
0.46	GO:0030424	axon
0.30	GO:0016020	membrane
0.30	GO:0071944	cell periphery

sp|P06768|RET2_RAT
Retinol-binding protein 2
Search

RBP2

0.97	Cellular retinol-binding protein type II

0.46	GO:0006776	vitamin A metabolic process
0.45	GO:0002138	retinoic acid biosynthetic process
0.35	GO:0042572	retinol metabolic process
0.35	GO:0008544	epidermis development
0.34	GO:0060972	left/right pattern formation
0.34	GO:0061371	determination of heart left/right asymmetry
0.34	GO:0009435	NAD biosynthetic process
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0043043	peptide biosynthetic process

0.72	GO:0008289	lipid binding
0.41	GO:0043178	alcohol binding
0.38	GO:0019842	vitamin binding
0.37	GO:0016779	nucleotidyltransferase activity
0.33	GO:0005198	structural molecule activity
0.33	GO:0005515	protein binding

0.42	GO:0005829	cytosol
0.34	GO:0030663	COPI-coated vesicle membrane
0.33	GO:0030117	membrane coat
0.33	GO:0000139	Golgi membrane
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016779

sp|P06866|HPT_RAT
Haptoglobin
Search

0.86	Haptoglobin

0.58	GO:0006508	proteolysis
0.53	GO:0007219	Notch signaling pathway
0.51	GO:0006953	acute-phase response
0.47	GO:0042742	defense response to bacterium
0.45	GO:0002376	immune system process
0.44	GO:0098869	cellular oxidant detoxification
0.40	GO:2000296	negative regulation of hydrogen peroxide catabolic process
0.39	GO:0051354	negative regulation of oxidoreductase activity
0.38	GO:0042542	response to hydrogen peroxide
0.38	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process

0.80	GO:0030492	hemoglobin binding
0.66	GO:0004252	serine-type endopeptidase activity
0.44	GO:0016209	antioxidant activity
0.39	GO:0004152	dihydroorotate dehydrogenase activity
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0005509	calcium ion binding
0.31	GO:0016740	transferase activity

0.61	GO:0005576	extracellular region
0.40	GO:0031838	haptoglobin-hemoglobin complex
0.36	GO:0031982	vesicle
0.36	GO:1990777	lipoprotein particle
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.66	EC:3.4.21	GO:0004252
0.39	KEGG:R01868	GO:0004152

sp|P06882|THYG_RAT
Thyroglobulin
Search

0.48	Thyroglobulin

0.83	GO:0015705	iodide transport
0.79	GO:0042403	thyroid hormone metabolic process
0.79	GO:0031641	regulation of myelination
0.78	GO:0030878	thyroid gland development
0.35	GO:0097105	presynaptic membrane assembly
0.34	GO:0097104	postsynaptic membrane assembly
0.34	GO:0007158	neuron cell-cell adhesion
0.34	GO:0048488	synaptic vesicle endocytosis
0.34	GO:0050804	modulation of chemical synaptic transmission
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.45	GO:0004104	cholinesterase activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0042043	neurexin family protein binding
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding
0.33	GO:0004872	receptor activity
0.30	GO:0042803	protein homodimerization activity
0.30	GO:0032403	protein complex binding
0.30	GO:0098772	molecular function regulator
0.30	GO:0043168	anion binding

0.66	GO:0005615	extracellular space
0.35	GO:0042579	microbody
0.34	GO:0005634	nucleus
0.33	GO:0009986	cell surface
0.33	GO:0045202	synapse
0.33	GO:0005887	integral component of plasma membrane
0.30	GO:0032991	macromolecular complex
0.30	GO:0005783	endoplasmic reticulum
0.30	GO:0005794	Golgi apparatus
0.30	GO:0048471	perinuclear region of cytoplasm

0.45

EC:3.1.1.8

GO:0004104

sp|P06883|GLUC_RAT
Glucagon
Search

GCG

0.97	Preproglucagon B

0.76	GO:0010469	regulation of receptor activity
0.62	GO:0010737	protein kinase A signaling
0.61	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.61	GO:1900118	negative regulation of execution phase of apoptosis
0.61	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.60	GO:0090280	positive regulation of calcium ion import
0.60	GO:0051571	positive regulation of histone H3-K4 methylation
0.60	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.59	GO:0032099	negative regulation of appetite
0.58	GO:0033138	positive regulation of peptidyl-serine phosphorylation

0.79	GO:0005179	hormone activity
0.53	GO:0042802	identical protein binding
0.52	GO:0031769	glucagon receptor binding
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.33	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.40	GO:0005737	cytoplasm
0.38	GO:0031983	vesicle lumen
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|P06907|MYP0_RAT
Myelin protein P0
Search

MPZ

0.97	Myelin protein zero

0.59	GO:0098743	cell aggregation
0.58	GO:0042552	myelination
0.55	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules
0.45	GO:0023052	signaling
0.44	GO:0007154	cell communication
0.43	GO:0051716	cellular response to stimulus
0.41	GO:0065007	biological regulation
0.39	GO:0045217	cell-cell junction maintenance
0.35	GO:0060028	convergent extension involved in axis elongation

0.35	GO:0000062	fatty-acyl-CoA binding
0.35	GO:0005515	protein binding
0.34	GO:0005198	structural molecule activity

0.77	GO:0043209	myelin sheath
0.67	GO:0005887	integral component of plasma membrane
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0005791	rough endoplasmic reticulum
0.38	GO:0005764	lysosome
0.33	GO:0005925	focal adhesion
0.33	GO:0009986	cell surface

sp|P06911|LCN5_RAT
Epididymal-specific lipocalin-5
Search

LCN5

0.92	Epididymal-specific lipocalin-5

0.65

GO:0042573

retinoic acid metabolic process

0.62	GO:0005501	retinoid binding
0.50	GO:0036094	small molecule binding
0.37	GO:0003723	RNA binding

0.63

GO:0005576

extracellular region

sp|P07092|GDN_RAT
Glia-derived nexin
Search

SERPINE2

0.97	Serine protease inhibitor clade E member 2

0.60	GO:0061108	seminal vesicle epithelium development
0.59	GO:0042628	mating plug formation
0.58	GO:0010757	negative regulation of plasminogen activation
0.57	GO:0090331	negative regulation of platelet aggregation
0.57	GO:0021683	cerebellar granular layer morphogenesis
0.57	GO:0010766	negative regulation of sodium ion transport
0.57	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.57	GO:0048505	regulation of timing of cell differentiation
0.57	GO:0048711	positive regulation of astrocyte differentiation
0.56	GO:0060384	innervation

0.54	GO:0004867	serine-type endopeptidase inhibitor activity
0.54	GO:0008201	heparin binding
0.50	GO:0005102	receptor binding
0.36	GO:0008233	peptidase activity
0.33	GO:0002020	protease binding
0.32	GO:0046872	metal ion binding

0.73	GO:0005615	extracellular space
0.58	GO:0031232	extrinsic component of external side of plasma membrane
0.56	GO:0031091	platelet alpha granule
0.55	GO:0031594	neuromuscular junction
0.50	GO:0031012	extracellular matrix
0.47	GO:0005829	cytosol
0.37	GO:1903561	extracellular vesicle
0.35	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

0.36

GO:0008233

sp|P07150|ANXA1_RAT
Annexin A1
Search

ANXA1

0.61

Annexin

0.72	GO:0043086	negative regulation of catalytic activity
0.62	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.62	GO:0045627	positive regulation of T-helper 1 cell differentiation
0.60	GO:0002548	monocyte chemotaxis
0.60	GO:0045920	negative regulation of exocytosis
0.60	GO:0014839	myoblast migration involved in skeletal muscle regeneration
0.60	GO:0032743	positive regulation of interleukin-2 production
0.60	GO:0071385	cellular response to glucocorticoid stimulus
0.60	GO:0097350	neutrophil clearance
0.60	GO:0033031	positive regulation of neutrophil apoptotic process

0.85	GO:0004859	phospholipase inhibitor activity
0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.58	GO:0098641	cadherin binding involved in cell-cell adhesion
0.57	GO:0048306	calcium-dependent protein binding
0.54	GO:0030674	protein binding, bridging
0.45	GO:0005198	structural molecule activity
0.43	GO:0033676	double-stranded DNA-dependent ATPase activity
0.41	GO:0036310	annealing helicase activity
0.40	GO:0003727	single-stranded RNA binding

0.62	GO:0031232	extrinsic component of external side of plasma membrane
0.58	GO:0016328	lateral plasma membrane
0.57	GO:0001533	cornified envelope
0.56	GO:0070062	extracellular exosome
0.56	GO:0016324	apical plasma membrane
0.56	GO:0042383	sarcolemma
0.55	GO:0031514	motile cilium
0.55	GO:0005913	cell-cell adherens junction
0.55	GO:0005884	actin filament
0.53	GO:0005768	endosome

sp|P07151|B2MG_RAT
Beta-2-microglobulin
Search

B2M

0.87	Beta-2-microglobulin

0.81	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.74	GO:0006955	immune response
0.57	GO:1904440	positive regulation of ferrous iron import across plasma membrane
0.57	GO:1904434	positive regulation of ferrous iron binding
0.57	GO:1904435	regulation of transferrin receptor binding
0.57	GO:0071283	cellular response to iron(III) ion
0.56	GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
0.56	GO:1900122	positive regulation of receptor binding
0.55	GO:0002726	positive regulation of T cell cytokine production
0.55	GO:1900121	negative regulation of receptor binding

0.48	GO:0042802	identical protein binding
0.32	GO:0046872	metal ion binding

0.81	GO:0042612	MHC class I protein complex
0.66	GO:0005576	extracellular region
0.55	GO:1990712	HFE-transferrin receptor complex
0.51	GO:0009897	external side of plasma membrane
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.37	GO:0030670	phagocytic vesicle membrane
0.37	GO:0005925	focal adhesion
0.36	GO:0031905	early endosome lumen
0.35	GO:1904724	tertiary granule lumen

sp|P07152|MMP10_RAT
Stromelysin-2
Search

MMP3

0.70	Matrix metalloproteinase

0.61	GO:0030574	collagen catabolic process
0.61	GO:0006508	proteolysis
0.55	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.53	GO:0032461	positive regulation of protein oligomerization
0.48	GO:0030334	regulation of cell migration
0.48	GO:0022617	extracellular matrix disassembly
0.46	GO:0003417	growth plate cartilage development
0.46	GO:0001958	endochondral ossification
0.45	GO:0030282	bone mineralization
0.43	GO:0042060	wound healing

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.48	GO:0005518	collagen binding
0.44	GO:0005509	calcium ion binding
0.41	GO:0001047	core promoter binding
0.37	GO:0004252	serine-type endopeptidase activity
0.37	GO:0043565	sequence-specific DNA binding
0.34	GO:0001968	fibronectin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.42	GO:0005615	extracellular space
0.37	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.37	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0005581	collagen trimer
0.35	GO:0030425	dendrite
0.34	GO:0044297	cell body
0.34	GO:0046581	intercellular canaliculus
0.34	GO:0005739	mitochondrion

0.70

GO:0004222

sp|P07153|RPN1_RAT
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Search

RPN1

0.69	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

0.74	GO:0006486	protein glycosylation
0.57	GO:0018196	peptidyl-asparagine modification
0.33	GO:0042886	amide transport
0.33	GO:0071702	organic substance transport

0.84	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.53	GO:0005791	rough endoplasmic reticulum
0.47	GO:0005829	cytosol
0.43	GO:1990234	transferase complex
0.41	GO:0042470	melanosome
0.37	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.1.119

GO:0004579

sp|P07154|CATL1_RAT
Cathepsin L1
Search

0.71	Cathepsin L

0.61	GO:0006508	proteolysis
0.51	GO:0010839	negative regulation of keratinocyte proliferation
0.50	GO:0046697	decidualization
0.50	GO:0031069	hair follicle morphogenesis
0.49	GO:2000249	regulation of actin cytoskeleton reorganization
0.47	GO:0044257	cellular protein catabolic process
0.45	GO:0097067	cellular response to thyroid hormone stimulus
0.45	GO:0030574	collagen catabolic process
0.44	GO:0051604	protein maturation
0.44	GO:0002250	adaptive immune response

0.72	GO:0008234	cysteine-type peptidase activity
0.51	GO:0042393	histone binding
0.47	GO:0097655	serpin family protein binding
0.45	GO:0001968	fibronectin binding
0.45	GO:0004175	endopeptidase activity
0.45	GO:0043394	proteoglycan binding
0.44	GO:0004180	carboxypeptidase activity
0.44	GO:0032403	protein complex binding
0.42	GO:0030984	kininogen binding
0.39	GO:0042277	peptide binding

0.54	GO:0005764	lysosome
0.51	GO:0005615	extracellular space
0.45	GO:0031410	cytoplasmic vesicle
0.45	GO:0005730	nucleolus
0.41	GO:0043204	perikaryon
0.41	GO:0005902	microvillus
0.40	GO:0009897	external side of plasma membrane
0.40	GO:0045177	apical part of cell
0.39	GO:0043005	neuron projection
0.38	GO:0012505	endomembrane system

0.72

GO:0008234

sp|P07171|CALB1_RAT
Calbindin
Search

CALB1

0.96	Cerebellar calbindin

0.74	GO:0055074	calcium ion homeostasis
0.61	GO:0072027	connecting tubule development
0.60	GO:0072221	metanephric distal convoluted tubule development
0.60	GO:0035502	metanephric part of ureteric bud development
0.60	GO:0072205	metanephric collecting duct development
0.59	GO:0007614	short-term memory
0.58	GO:1900271	regulation of long-term synaptic potentiation
0.58	GO:0007616	long-term memory
0.58	GO:0010842	retina layer formation
0.55	GO:0007626	locomotory behavior

0.70	GO:0005509	calcium ion binding
0.46	GO:0008270	zinc ion binding
0.43	GO:0005499	vitamin D binding
0.33	GO:0005515	protein binding

0.55	GO:0043005	neuron projection
0.55	GO:0043025	neuronal cell body
0.54	GO:0045202	synapse
0.53	GO:0120038	plasma membrane bounded cell projection part
0.52	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.44	GO:0005921	gap junction
0.36	GO:0070062	extracellular exosome
0.34	GO:0098590	plasma membrane region
0.34	GO:0012506	vesicle membrane

sp|P07174|TNR16_RAT
Tumor necrosis factor receptor superfamily member 16
Search

NGFR

0.95	Nerve growth factor receptor b

0.75	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.73	GO:1904646	cellular response to amyloid-beta
0.72	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.71	GO:0051402	neuron apoptotic process
0.70	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.69	GO:0007266	Rho protein signal transduction
0.69	GO:1900182	positive regulation of protein localization to nucleus
0.54	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.53	GO:0010977	negative regulation of neuron projection development
0.52	GO:0032496	response to lipopolysaccharide

0.73	GO:0005035	death receptor activity
0.70	GO:0015026	coreceptor activity
0.65	GO:0031625	ubiquitin protein ligase binding
0.65	GO:0005516	calmodulin binding
0.56	GO:0048406	nerve growth factor binding

0.50	GO:0043005	neuron projection
0.49	GO:0005886	plasma membrane
0.43	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P07308|ACOD1_RAT
Acyl-CoA desaturase 1
Search

SCD

0.47	River buffalo stearoyl CoA desaturase

0.70	GO:0006633	fatty acid biosynthetic process
0.58	GO:0033559	unsaturated fatty acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0070542	response to fatty acid
0.40	GO:1903699	tarsal gland development
0.39	GO:0034435	cholesterol esterification
0.39	GO:0050872	white fat cell differentiation
0.39	GO:0044130	negative regulation of growth of symbiont in host
0.39	GO:0033561	regulation of water loss via skin
0.39	GO:0050873	brown fat cell differentiation

0.80	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
0.45	GO:0005506	iron ion binding
0.33	GO:0008173	RNA methyltransferase activity
0.32	GO:0005102	receptor binding

0.50	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005730	nucleolus
0.36	GO:0031090	organelle membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.80

EC:1.14.19

GO:0016717

sp|P07314|GGT1_RAT
Gamma-glutamyltranspeptidase 1
Search

GGT1

0.70	Glutathione hydrolase 1 proenzyme

0.79	GO:0006751	glutathione catabolic process
0.61	GO:0006508	proteolysis
0.50	GO:0050727	regulation of inflammatory response
0.50	GO:0006750	glutathione biosynthetic process
0.49	GO:0007283	spermatogenesis
0.47	GO:0019344	cysteine biosynthetic process
0.46	GO:0002682	regulation of immune system process
0.45	GO:1901748	leukotriene D4 metabolic process
0.43	GO:0019370	leukotriene biosynthetic process
0.39	GO:0051604	protein maturation

0.80	GO:0036374	glutathione hydrolase activity
0.41	GO:0103068	leukotriene C4 gamma-glutamyl transferase activity
0.41	GO:0102953	hypoglycin A gamma-glutamyl transpeptidase activity
0.41	GO:0002951	leukotriene-C(4) hydrolase
0.41	GO:0000048	peptidyltransferase activity
0.33	GO:0005515	protein binding

0.47	GO:0031982	vesicle
0.40	GO:0043230	extracellular organelle
0.38	GO:0005615	extracellular space
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005783	endoplasmic reticulum

0.80	EC:3.4.19.13	GO:0036374
0.80	KEGG:R00494	GO:0036374

sp|P07323|ENOG_RAT
Gamma-enolase
Search

ENO2

0.95	Neuron-specific enolase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0046496	nicotinamide nucleotide metabolic process
0.36	GO:0043403	skeletal muscle tissue regeneration
0.36	GO:0019319	hexose biosynthetic process
0.36	GO:0006006	glucose metabolic process
0.35	GO:0007568	aging
0.35	GO:0042493	response to drug
0.35	GO:0051290	protein heterotetramerization

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0019899	enzyme binding

0.77	GO:0000015	phosphopyruvate hydratase complex
0.54	GO:0001917	photoreceptor inner segment
0.53	GO:0043204	perikaryon
0.52	GO:0043209	myelin sheath
0.43	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0030426	growth cone
0.34	GO:0099738	cell cortex region
0.34	GO:0045121	membrane raft
0.34	GO:0044456	synapse part

0.78

EC:4.2.1.11

GO:0004634

sp|P07335|KCRB_RAT
Creatine kinase B-type
Search

CKB

0.93	Brain-subtype creatine kinase

0.56	GO:0016310	phosphorylation
0.44	GO:0030644	cellular chloride ion homeostasis
0.41	GO:0007420	brain development
0.37	GO:0048857	neural nucleus development
0.35	GO:0046314	phosphocreatine biosynthetic process
0.35	GO:0006600	creatine metabolic process
0.34	GO:0009408	response to heat
0.34	GO:0006754	ATP biosynthetic process

0.59	GO:0004111	creatine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031625	ubiquitin protein ligase binding

0.50	GO:0043209	myelin sheath
0.47	GO:0005615	extracellular space
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.38	GO:0043230	extracellular organelle
0.36	GO:0005634	nucleus
0.35	GO:0031982	vesicle

0.59	EC:2.7.3.2	GO:0004111
0.59	KEGG:R01881	GO:0004111

sp|P07338|CTRB1_RAT
Chymotrypsinogen B
Search

0.83	Chymotrypsinogen B

0.61	GO:0006508	proteolysis
0.43	GO:0007586	digestion
0.37	GO:0022617	extracellular matrix disassembly
0.35	GO:0032094	response to food
0.35	GO:0009235	cobalamin metabolic process
0.35	GO:0007584	response to nutrient
0.35	GO:0043434	response to peptide hormone
0.35	GO:0043065	positive regulation of apoptotic process
0.34	GO:0034097	response to cytokine
0.34	GO:0030163	protein catabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0097655	serpin family protein binding
0.33	GO:0005509	calcium ion binding

0.40	GO:0005615	extracellular space
0.35	GO:0097180	serine protease inhibitor complex
0.35	GO:0005764	lysosome

0.69

GO:0004252

sp|P07340|AT1B1_RAT
Sodium/potassium-transporting ATPase subunit beta-1
Search

ATP1B1

0.80	Sodium/potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.61	GO:1903281	positive regulation of calcium:sodium antiporter activity
0.61	GO:1903288	positive regulation of potassium ion import
0.61	GO:1903275	positive regulation of sodium ion export
0.61	GO:1903276	regulation of sodium ion export across plasma membrane
0.60	GO:0055119	relaxation of cardiac muscle
0.60	GO:0006883	cellular sodium ion homeostasis
0.60	GO:0086009	membrane repolarization
0.59	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.58	GO:0005391	sodium:potassium-exchanging ATPase activity
0.58	GO:0051117	ATPase binding
0.56	GO:0008022	protein C-terminus binding
0.55	GO:0001671	ATPase activator activity
0.55	GO:0031402	sodium ion binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0030955	potassium ion binding
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.58	GO:0014704	intercalated disc
0.57	GO:0042383	sarcolemma
0.56	GO:0043209	myelin sheath
0.56	GO:0016323	basolateral plasma membrane
0.55	GO:0016324	apical plasma membrane
0.41	GO:0005901	caveola
0.37	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome

0.58

GO:0005391

sp|P07379|PCKGC_RAT
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
Search

PCK1

0.97	Phosphoenolpyruvate carboxykinase, cytosolic

0.73	GO:0019319	hexose biosynthetic process
0.71	GO:0006006	glucose metabolic process
0.59	GO:0046327	glycerol biosynthetic process from pyruvate
0.58	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
0.58	GO:0051365	cellular response to potassium ion starvation
0.54	GO:0032868	response to insulin
0.52	GO:0006475	internal protein amino acid acetylation
0.52	GO:0016310	phosphorylation
0.46	GO:0009746	response to hexose
0.43	GO:0048878	chemical homeostasis

0.83	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.66	GO:0005525	GTP binding
0.54	GO:0016301	kinase activity
0.49	GO:0030145	manganese ion binding
0.48	GO:0043177	organic acid binding
0.45	GO:0000287	magnesium ion binding
0.38	GO:0019003	GDP binding
0.36	GO:0019157	malate oxidase activity
0.35	GO:0050692	DBD domain binding
0.35	GO:0051379	epinephrine binding

0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0005739	mitochondrion

0.83	EC:4.1.1.32	GO:0004613
0.36	KEGG:R00360	GO:0019157

sp|P07448|DFTS_RAT
Dentinal fluid transport-stimulating peptide
Search

0.40	Dentinal fluid transport-stimulating peptide

0.75

GO:0010469

regulation of receptor activity

0.79

GO:0005179

hormone activity

sp|P07483|FABPH_RAT
Fatty acid-binding protein, heart
Search

FABP3

0.78	Fatty acid binding protein 3, muscle and heart (Mammary-derived growth inhibitor)

0.59	GO:0042632	cholesterol homeostasis
0.54	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.54	GO:0050727	regulation of inflammatory response
0.54	GO:0055091	phospholipid homeostasis
0.54	GO:0044539	long-chain fatty acid import
0.53	GO:0046320	regulation of fatty acid oxidation
0.52	GO:0050872	white fat cell differentiation
0.52	GO:0071285	cellular response to lithium ion
0.51	GO:0050873	brown fat cell differentiation
0.50	GO:0001816	cytokine production

0.70	GO:0008289	lipid binding
0.58	GO:0033293	monocarboxylic acid binding
0.48	GO:0008092	cytoskeletal protein binding
0.40	GO:0005324	long-chain fatty acid transporter activity

0.50	GO:0005615	extracellular space
0.40	GO:0016528	sarcoplasm
0.38	GO:1903561	extracellular vesicle
0.38	GO:0005829	cytosol
0.37	GO:0043025	neuronal cell body
0.36	GO:0005911	cell-cell junction
0.36	GO:0005811	lipid droplet
0.36	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0042995	cell projection
0.34	GO:0043233	organelle lumen

sp|P07490|GON1_RAT
Progonadoliberin-1
Search

GNRH1

0.90	Gonadotropin-releasing hormone

0.76	GO:0010469	regulation of receptor activity
0.71	GO:2000354	regulation of ovarian follicle development
0.70	GO:2001223	negative regulation of neuron migration
0.66	GO:0045471	response to ethanol
0.61	GO:0048545	response to steroid hormone
0.47	GO:1990637	response to prolactin
0.47	GO:0060255	regulation of macromolecule metabolic process
0.46	GO:0044849	estrous cycle
0.46	GO:0033087	negative regulation of immature T cell proliferation
0.46	GO:0035864	response to potassium ion

0.87	GO:0005183	gonadotropin hormone-releasing hormone activity
0.37	GO:0031530	gonadotropin-releasing hormone receptor binding

0.66	GO:0005576	extracellular region
0.48	GO:1990008	neurosecretory vesicle
0.46	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.46	GO:0043204	perikaryon
0.44	GO:0043679	axon terminus
0.43	GO:0030425	dendrite
0.42	GO:0005798	Golgi-associated vesicle
0.38	GO:0005739	mitochondrion
0.37	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|P07522|EGF_RAT
Pro-epidermal growth factor
Search

EGF

0.97	Pro-epidermal growth factor

0.73	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification
0.68	GO:0060070	canonical Wnt signaling pathway
0.63	GO:0010469	regulation of receptor activity
0.63	GO:0007262	STAT protein import into nucleus
0.60	GO:1900127	positive regulation of hyaluronan biosynthetic process
0.60	GO:0090370	negative regulation of cholesterol efflux
0.59	GO:0035413	positive regulation of catenin import into nucleus
0.59	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation
0.58	GO:0043388	positive regulation of DNA binding
0.58	GO:0070371	ERK1 and ERK2 cascade

0.70	GO:0005509	calcium ion binding
0.69	GO:0017147	Wnt-protein binding
0.69	GO:0042813	Wnt-activated receptor activity
0.65	GO:0008083	growth factor activity
0.57	GO:0005154	epidermal growth factor receptor binding
0.39	GO:0004713	protein tyrosine kinase activity
0.37	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0005041	low-density lipoprotein receptor activity

0.64	GO:0043235	receptor complex
0.55	GO:0070062	extracellular exosome
0.44	GO:0005886	plasma membrane
0.39	GO:0005765	lysosomal membrane
0.37	GO:0031093	platelet alpha granule lumen
0.36	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0097443	sorting endosome
0.34	GO:1990666	PCSK9-LDLR complex
0.34	GO:0005770	late endosome
0.34	GO:0045177	apical part of cell

0.39	EC:2.7.10	GO:0004713
0.37	KEGG:R04545	GO:0046934

sp|P07631|SUH2_RAT
Probable alcohol sulfotransferase
Search

0.53	Bile salt sulfotransferase

0.53	GO:0051923	sulfation
0.50	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.49	GO:0008202	steroid metabolic process
0.48	GO:0006068	ethanol catabolic process
0.45	GO:0042403	thyroid hormone metabolic process
0.42	GO:0006805	xenobiotic metabolic process
0.41	GO:0017085	response to insecticide
0.40	GO:0014823	response to activity
0.40	GO:0071305	cellular response to vitamin D
0.39	GO:0045606	positive regulation of epidermal cell differentiation

0.78	GO:0008146	sulfotransferase activity
0.42	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.39	GO:1990239	steroid hormone binding
0.38	GO:0015485	cholesterol binding
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding
0.32	GO:0003735	structural constituent of ribosome

0.45	GO:0005829	cytosol
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:0012505	endomembrane system
0.35	GO:0043230	extracellular organelle
0.34	GO:0043229	intracellular organelle
0.34	GO:0005615	extracellular space
0.33	GO:0031975	envelope
0.32	GO:0044422	organelle part
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043228	non-membrane-bounded organelle

0.78

GO:0008146

sp|P07632|SODC_RAT
Superoxide dismutase [Cu-Zn]
Search

SOD1

0.54	Superoxide dismutase [Cu-Zn]

0.75	GO:0006801	superoxide metabolic process
0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.69	GO:0098869	cellular oxidant detoxification
0.58	GO:0045541	negative regulation of cholesterol biosynthetic process
0.57	GO:0060087	relaxation of vascular smooth muscle
0.56	GO:0050665	hydrogen peroxide biosynthetic process
0.56	GO:0060088	auditory receptor cell stereocilium organization
0.56	GO:0032287	peripheral nervous system myelin maintenance
0.56	GO:0060052	neurofilament cytoskeleton organization

0.77	GO:0004784	superoxide dismutase activity
0.58	GO:0030346	protein phosphatase 2B binding
0.54	GO:0046872	metal ion binding
0.52	GO:0048365	Rac GTPase binding
0.51	GO:0051087	chaperone binding
0.48	GO:0042802	identical protein binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0004842	ubiquitin-protein transferase activity

0.56	GO:0032839	dendrite cytoplasm
0.53	GO:0043025	neuronal cell body
0.51	GO:0005615	extracellular space
0.51	GO:1904115	axon cytoplasm
0.50	GO:0043209	myelin sheath
0.50	GO:0031012	extracellular matrix
0.49	GO:0031410	cytoplasmic vesicle
0.48	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.46	GO:0005634	nucleus

0.77	EC:1.15.1.1	GO:0004784
0.34	KEGG:R03876	GO:0004842

sp|P07633|PCCB_RAT
Propionyl-CoA carboxylase beta chain, mitochondrial
Search

PCCB

0.94	Propionyl coenzyme A carboxylase, beta polypeptide

0.44

GO:0009062

fatty acid catabolic process

0.62

GO:0016874

ligase activity

0.36

GO:0005739

mitochondrion

0.62

EC:6

GO:0016874

sp|P07647|KLK9_RAT
Submandibular glandular kallikrein-9
Search

0.93	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.41	GO:0002675	positive regulation of acute inflammatory response
0.40	GO:0007584	response to nutrient
0.40	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043065	positive regulation of apoptotic process
0.39	GO:0032501	multicellular organismal process
0.38	GO:0051604	protein maturation
0.38	GO:0072672	neutrophil extravasation
0.37	GO:0035296	regulation of tube diameter
0.37	GO:0045217	cell-cell junction maintenance

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0005102	receptor binding
0.37	GO:0090729	toxin activity
0.36	GO:0030545	receptor regulator activity
0.35	GO:0046872	metal ion binding
0.35	GO:0019899	enzyme binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0043395	heparan sulfate proteoglycan binding

0.47	GO:0005615	extracellular space
0.42	GO:0030141	secretory granule
0.40	GO:0097223	sperm part
0.40	GO:1903561	extracellular vesicle
0.40	GO:0045177	apical part of cell
0.39	GO:0043234	protein complex
0.38	GO:0005634	nucleus
0.37	GO:0005766	primary lysosome
0.37	GO:0060205	cytoplasmic vesicle lumen
0.37	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P07687|HYEP_RAT
Epoxide hydrolase 1
Search

EPHX1

0.56	Epoxide hydrolase

0.59	GO:0019439	aromatic compound catabolic process
0.57	GO:0097176	epoxide metabolic process
0.46	GO:0014070	response to organic cyclic compound
0.37	GO:0009636	response to toxic substance
0.35	GO:0001889	liver development
0.35	GO:0070887	cellular response to chemical stimulus
0.35	GO:0034312	diol biosynthetic process
0.35	GO:0033993	response to lipid
0.34	GO:0009725	response to hormone
0.34	GO:0071495	cellular response to endogenous stimulus

0.80	GO:0033961	cis-stilbene-oxide hydrolase activity
0.55	GO:0004301	epoxide hydrolase activity
0.34	GO:0019899	enzyme binding

0.62	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:3.3.2.9

GO:0033961

sp|P07722|MAG_RAT
Myelin-associated glycoprotein
Search

MAG

0.97	Sialic-acid binding protein-4

0.61	GO:0031643	positive regulation of myelination
0.60	GO:0022010	central nervous system myelination
0.57	GO:0010977	negative regulation of neuron projection development
0.57	GO:0043524	negative regulation of neuron apoptotic process
0.42	GO:0048711	positive regulation of astrocyte differentiation
0.42	GO:0071260	cellular response to mechanical stimulus
0.42	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.41	GO:0030516	regulation of axon extension
0.41	GO:0048640	negative regulation of developmental growth
0.41	GO:0030308	negative regulation of cell growth

0.62	GO:1905576	ganglioside GT1b binding
0.61	GO:0033691	sialic acid binding
0.53	GO:0042802	identical protein binding
0.49	GO:0046983	protein dimerization activity
0.41	GO:0030246	carbohydrate binding
0.40	GO:0019901	protein kinase binding
0.39	GO:0005102	receptor binding
0.35	GO:0005509	calcium ion binding

0.60	GO:0043218	compact myelin
0.59	GO:0033270	paranode region of axon
0.48	GO:0005887	integral component of plasma membrane
0.44	GO:0097453	mesaxon
0.43	GO:0035749	myelin sheath adaxonal region
0.40	GO:0045121	membrane raft
0.34	GO:0005737	cytoplasm
0.34	GO:0005604	basement membrane
0.33	GO:0030054	cell junction
0.32	GO:0019013	viral nucleocapsid

sp|P07725|CD8A_RAT
T-cell surface glycoprotein CD8 alpha chain
Search

CD8A

0.83	T-cell surface glycoprotein CD8 alpha chain

0.59	GO:0045065	cytotoxic T cell differentiation
0.55	GO:0002456	T cell mediated immunity
0.48	GO:0007166	cell surface receptor signaling pathway
0.45	GO:0050850	positive regulation of calcium-mediated signaling
0.43	GO:0051607	defense response to virus
0.39	GO:0006954	inflammatory response
0.36	GO:0019882	antigen processing and presentation
0.35	GO:0050776	regulation of immune response

0.42	GO:0042803	protein homodimerization activity
0.41	GO:0019901	protein kinase binding
0.38	GO:0042288	MHC class I protein binding
0.37	GO:0015026	coreceptor activity

0.61	GO:0009897	external side of plasma membrane
0.59	GO:0044853	plasma membrane raft
0.43	GO:0044214	spanning component of plasma membrane
0.37	GO:0042101	T cell receptor complex
0.35	GO:0005576	extracellular region

sp|P07727|GLRA1_RAT
Glycine receptor subunit alpha-1
Search

GLRA1

0.96	Glycine receptor subunit alpha-1

0.71	GO:0060079	excitatory postsynaptic potential
0.69	GO:1902476	chloride transmembrane transport
0.59	GO:0060012	synaptic transmission, glycinergic
0.59	GO:0051970	negative regulation of transmission of nerve impulse
0.58	GO:0071294	cellular response to zinc ion
0.58	GO:0071361	cellular response to ethanol
0.57	GO:2000344	positive regulation of acrosome reaction
0.57	GO:0060080	inhibitory postsynaptic potential
0.57	GO:0060013	righting reflex
0.57	GO:0002087	regulation of respiratory gaseous exchange by neurological system process

0.85	GO:0016594	glycine binding
0.79	GO:0016934	extracellularly glycine-gated chloride channel activity
0.76	GO:0022824	transmitter-gated ion channel activity
0.69	GO:0004888	transmembrane signaling receptor activity
0.60	GO:0043210	alkanesulfonate binding
0.45	GO:0008270	zinc ion binding
0.36	GO:0042802	identical protein binding

0.71	GO:0045211	postsynaptic membrane
0.66	GO:0005887	integral component of plasma membrane
0.57	GO:0060077	inhibitory synapse
0.53	GO:0043025	neuronal cell body
0.53	GO:0009897	external side of plasma membrane
0.52	GO:0043005	neuron projection
0.42	GO:0034707	chloride channel complex
0.42	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0030054	cell junction

sp|P07756|CPSM_RAT
Carbamoyl-phosphate synthase [ammonia], mitochondrial
Search

CPS1

0.63	Carbamoyl-phosphate synthetase I

0.71	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.68	GO:0006541	glutamine metabolic process
0.61	GO:0070409	carbamoyl phosphate biosynthetic process
0.60	GO:1903718	cellular response to ammonia
0.57	GO:0019433	triglyceride catabolic process
0.57	GO:0042311	vasodilation
0.55	GO:0046209	nitric oxide metabolic process
0.55	GO:0050667	homocysteine metabolic process
0.55	GO:0032496	response to lipopolysaccharide
0.54	GO:0000050	urea cycle

0.74	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
0.66	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0046872	metal ion binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0072341	modified amino acid binding
0.40	GO:0016595	glutamate binding
0.37	GO:0005543	phospholipid binding

0.55	GO:0042645	mitochondrial nucleoid
0.51	GO:0005730	nucleolus
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.35	GO:0043234	protein complex

0.74	EC:6.3.5.5	GO:0004088
0.66	KEGG:R00149	GO:0004087

sp|P07808|NPY_RAT
Pro-neuropeptide Y
Search

NPY

0.95	Prepro-neuropeptide Y

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0007218	neuropeptide signaling pathway
0.56	GO:0021954	central nervous system neuron development
0.56	GO:0021987	cerebral cortex development
0.55	GO:0008217	regulation of blood pressure
0.53	GO:0031175	neuron projection development
0.49	GO:0032098	regulation of appetite
0.48	GO:0007631	feeding behavior
0.45	GO:0007267	cell-cell signaling
0.44	GO:0032097	positive regulation of response to food

0.79	GO:0005179	hormone activity
0.56	GO:0001664	G-protein coupled receptor binding
0.35	GO:0005246	calcium channel regulator activity
0.34	GO:0004930	G-protein coupled receptor activity

0.66	GO:0005576	extracellular region
0.49	GO:0005794	Golgi apparatus
0.35	GO:0043204	perikaryon
0.35	GO:0043195	terminal bouton
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P07824|ARGI1_RAT
Arginase-1
Search

ARG1

0.58	Arginase-2, mitochondrial

0.85	GO:0000050	urea cycle
0.70	GO:0006525	arginine metabolic process
0.64	GO:0002829	negative regulation of type 2 immune response
0.63	GO:0042130	negative regulation of T cell proliferation
0.61	GO:0002831	regulation of response to biotic stimulus
0.60	GO:0001818	negative regulation of cytokine production
0.59	GO:0070960	positive regulation of neutrophil mediated cytotoxicity
0.58	GO:0032101	regulation of response to external stimulus
0.58	GO:0060331	negative regulation of response to interferon-gamma
0.57	GO:0043900	regulation of multi-organism process

0.83	GO:0004053	arginase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0003933	GTP cyclohydrolase activity
0.35	GO:0050998	nitric-oxide synthase binding

0.49	GO:0005615	extracellular space
0.43	GO:0005739	mitochondrion
0.38	GO:0043025	neuronal cell body
0.37	GO:0043005	neuron projection
0.37	GO:0031968	organelle outer membrane
0.37	GO:1903561	extracellular vesicle
0.36	GO:0035580	specific granule lumen
0.36	GO:0035578	azurophil granule lumen
0.34	GO:0005634	nucleus
0.34	GO:0005829	cytosol

0.83

EC:3.5.3.1

GO:0004053

sp|P07825|SYPH_RAT
Synaptophysin
Search

SYP

0.94	Synaptophysin a

0.76	GO:0048168	regulation of neuronal synaptic plasticity
0.52	GO:0048488	synaptic vesicle endocytosis
0.47	GO:0071310	cellular response to organic substance
0.39	GO:2000474	regulation of opioid receptor signaling pathway
0.38	GO:0045920	negative regulation of exocytosis
0.36	GO:0048499	synaptic vesicle membrane organization
0.36	GO:0016188	synaptic vesicle maturation
0.35	GO:0043029	T cell homeostasis
0.35	GO:0050856	regulation of T cell receptor signaling pathway
0.35	GO:0007601	visual perception

0.53	GO:0042169	SH2 domain binding
0.52	GO:0015485	cholesterol binding
0.48	GO:0042802	identical protein binding
0.36	GO:0051020	GTPase binding
0.36	GO:0008331	high voltage-gated calcium channel activity
0.35	GO:0043621	protein self-association
0.33	GO:0008270	zinc ion binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.82	GO:0008021	synaptic vesicle
0.58	GO:0099501	exocytic vesicle membrane
0.53	GO:0060076	excitatory synapse
0.52	GO:0042734	presynaptic membrane
0.52	GO:0043195	terminal bouton
0.52	GO:0031594	neuromuscular junction
0.51	GO:0048786	presynaptic active zone
0.47	GO:0031301	integral component of organelle membrane
0.39	GO:0030054	cell junction
0.38	GO:0042584	chromaffin granule membrane

sp|P07861|NEP_RAT
Neprilysin
Search

MME

0.91	Membrane metallo-endopeptidase

0.62	GO:0071492	cellular response to UV-A
0.61	GO:0006508	proteolysis
0.61	GO:0071493	cellular response to UV-B
0.60	GO:0046449	creatinine metabolic process
0.60	GO:0090399	replicative senescence
0.60	GO:0050435	amyloid-beta metabolic process
0.58	GO:0019233	sensory perception of pain
0.56	GO:0001822	kidney development
0.55	GO:0071345	cellular response to cytokine stimulus
0.40	GO:0097242	amyloid-beta clearance

0.70	GO:0004222	metalloendopeptidase activity
0.48	GO:0008238	exopeptidase activity
0.48	GO:0042277	peptide binding
0.47	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.58	GO:0005903	brush border
0.57	GO:0044306	neuron projection terminus
0.56	GO:0008021	synaptic vesicle
0.55	GO:0030425	dendrite
0.55	GO:0030424	axon
0.43	GO:0005886	plasma membrane
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.35	GO:0030667	secretory granule membrane
0.33	GO:0005794	Golgi apparatus

0.70

GO:0004222

sp|P07867|LIPC_RAT
Hepatic triacylglycerol lipase
Search

LIPC

0.97	Hepatic triacylglycerol lipase

0.61	GO:0006629	lipid metabolic process
0.55	GO:0034372	very-low-density lipoprotein particle remodeling
0.55	GO:0034374	low-density lipoprotein particle remodeling
0.55	GO:0034375	high-density lipoprotein particle remodeling
0.54	GO:0070328	triglyceride homeostasis
0.53	GO:0042632	cholesterol homeostasis
0.53	GO:0030301	cholesterol transport
0.50	GO:1902652	secondary alcohol metabolic process
0.46	GO:0072330	monocarboxylic acid biosynthetic process
0.44	GO:0044248	cellular catabolic process

0.77	GO:0004806	triglyceride lipase activity
0.41	GO:0008201	heparin binding
0.38	GO:0034185	apolipoprotein binding
0.38	GO:0030169	low-density lipoprotein particle binding
0.37	GO:0035478	chylomicron binding
0.36	GO:0004620	phospholipase activity
0.36	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:0047372	acylglycerol lipase activity
0.35	GO:0008289	lipid binding
0.34	GO:0016746	transferase activity, transferring acyl groups

0.64	GO:0005576	extracellular region
0.41	GO:1990777	lipoprotein particle
0.36	GO:0005902	microvillus
0.35	GO:0005770	late endosome
0.35	GO:0005769	early endosome
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0009986	cell surface

0.77

EC:3.1.1.3

GO:0004806

sp|P07871|THIKB_RAT
3-ketoacyl-CoA thiolase B, peroxisomal
Search

ACAA1

0.84	Acetyl-Coenzyme A acyltransferase 1

0.70	GO:0008206	bile acid metabolic process
0.67	GO:0000038	very long-chain fatty acid metabolic process
0.63	GO:0006635	fatty acid beta-oxidation

0.75	GO:0016401	palmitoyl-CoA oxidase activity
0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.63

GO:0042579

microbody

0.75

EC:1.3.3

GO:0016401

sp|P07872|ACOX1_RAT
Peroxisomal acyl-coenzyme A oxidase 1
Search

ACOX1

0.61	Acyl-coenzyme A oxidase

0.77	GO:0006635	fatty acid beta-oxidation
0.57	GO:0006692	prostanoid metabolic process
0.55	GO:0000038	very long-chain fatty acid metabolic process
0.52	GO:0007283	spermatogenesis
0.44	GO:0006091	generation of precursor metabolites and energy
0.40	GO:2000189	positive regulation of cholesterol homeostasis
0.38	GO:0016559	peroxisome fission
0.38	GO:0055088	lipid homeostasis
0.36	GO:0036109	alpha-linolenic acid metabolic process
0.34	GO:0019216	regulation of lipid metabolic process

0.82	GO:0003997	acyl-CoA oxidase activity
0.72	GO:0071949	FAD binding
0.55	GO:0047485	protein N-terminus binding
0.55	GO:0030165	PDZ domain binding
0.49	GO:0005102	receptor binding
0.43	GO:0003995	acyl-CoA dehydrogenase activity
0.35	GO:0005504	fatty acid binding
0.34	GO:0042803	protein homodimerization activity

0.76	GO:0005777	peroxisome
0.52	GO:0031903	microbody membrane
0.49	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.35	GO:0031907	microbody lumen

0.82

EC:1.3.3.6

GO:0003997

sp|P07882|CEL_RAT
Bile salt-activated lipase
Search

CEL

0.44	Carboxylic ester hydrolase

0.62	GO:0006629	lipid metabolic process
0.44	GO:1901565	organonitrogen compound catabolic process
0.43	GO:0044248	cellular catabolic process
0.42	GO:0043603	cellular amide metabolic process
0.36	GO:0030299	intestinal cholesterol absorption
0.35	GO:0006775	fat-soluble vitamin metabolic process
0.35	GO:0016049	cell growth
0.35	GO:1902652	secondary alcohol metabolic process
0.34	GO:0046164	alcohol catabolic process
0.34	GO:0030154	cell differentiation

0.60	GO:0016788	hydrolase activity, acting on ester bonds
0.33	GO:0005515	protein binding

0.34	GO:0005794	Golgi apparatus
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.60

EC:3.1

GO:0016788

sp|P07895|SODM_RAT
Superoxide dismutase [Mn], mitochondrial
Search

SOD2

0.46	Superoxide dismutase

0.76	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0001306	age-dependent response to oxidative stress
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0003070	regulation of systemic arterial blood pressure by neurotransmitter
0.49	GO:0048773	erythrophore differentiation
0.48	GO:0003085	negative regulation of systemic arterial blood pressure
0.47	GO:0001836	release of cytochrome c from mitochondria

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.37	GO:0042802	identical protein binding
0.37	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding
0.34	GO:0003677	DNA binding

0.45	GO:0043209	myelin sheath
0.44	GO:0005759	mitochondrial matrix
0.39	GO:0031966	mitochondrial membrane
0.39	GO:0019866	organelle inner membrane
0.36	GO:0009295	nucleoid
0.36	GO:0070062	extracellular exosome
0.34	GO:0043232	intracellular non-membrane-bounded organelle

0.77

EC:1.15.1.1

GO:0004784

sp|P07896|ECHP_RAT
Peroxisomal bifunctional enzyme
Search

EHHADH

0.77	Peroxisomal bifunctional enzyme

0.69	GO:0006631	fatty acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0006475	internal protein amino acid acetylation
0.51	GO:0044242	cellular lipid catabolic process
0.50	GO:0030258	lipid modification
0.49	GO:0072329	monocarboxylic acid catabolic process
0.38	GO:0035383	thioester metabolic process
0.36	GO:0006732	coenzyme metabolic process
0.34	GO:0006793	phosphorus metabolic process

0.76	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.52	GO:0004165	dodecenoyl-CoA delta-isomerase activity
0.49	GO:0004300	enoyl-CoA hydratase activity
0.46	GO:0005102	receptor binding
0.46	GO:0019899	enzyme binding
0.43	GO:0070403	NAD+ binding
0.41	GO:0016508	long-chain-enoyl-CoA hydratase activity

0.51	GO:0005777	peroxisome
0.42	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0031907	microbody lumen
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:1.1.1.35

GO:0003857

sp|P07897|PGCA_RAT
Aggrecan core protein
Search

ACAN

0.94	Aggrecan core protein isoform B

0.72	GO:0007155	cell adhesion
0.64	GO:0001502	cartilage condensation
0.64	GO:0002063	chondrocyte development
0.63	GO:0030199	collagen fibril organization
0.62	GO:0030166	proteoglycan biosynthetic process
0.59	GO:0007507	heart development
0.50	GO:0007417	central nervous system development
0.41	GO:0060591	chondroblast differentiation
0.40	GO:0009629	response to gravity
0.40	GO:0010447	response to acidic pH

0.84	GO:0005540	hyaluronic acid binding
0.60	GO:0005509	calcium ion binding
0.52	GO:0005201	extracellular matrix structural constituent
0.43	GO:0030246	carbohydrate binding
0.38	GO:0005515	protein binding

0.60	GO:0005604	basement membrane
0.55	GO:0005615	extracellular space
0.41	GO:0072534	perineuronal net
0.39	GO:0043025	neuronal cell body
0.39	GO:0043005	neuron projection
0.37	GO:0043202	lysosomal lumen
0.37	GO:0005796	Golgi lumen
0.30	GO:0016020	membrane

sp|P07936|NEUM_RAT
Neuromodulin
Search

GAP43

0.93	Neuromodulin

0.78	GO:0040008	regulation of growth
0.58	GO:0016198	axon choice point recognition
0.58	GO:0051489	regulation of filopodium assembly
0.55	GO:0010001	glial cell differentiation
0.54	GO:0045165	cell fate commitment
0.43	GO:0042246	tissue regeneration
0.40	GO:0007339	binding of sperm to zona pellucida
0.40	GO:0031103	axon regeneration
0.35	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway

0.46	GO:0005516	calmodulin binding
0.42	GO:0035727	lysophosphatidic acid binding
0.41	GO:0001786	phosphatidylserine binding
0.39	GO:1901981	phosphatidylinositol phosphate binding

0.61	GO:0031527	filopodium membrane
0.57	GO:0014069	postsynaptic density
0.54	GO:0043005	neuron projection
0.46	GO:0030427	site of polarized growth
0.44	GO:0030054	cell junction
0.39	GO:0005737	cytoplasm
0.37	GO:0097060	synaptic membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0098793	presynapse

sp|P07943|ALDR_RAT
Aldose reductase
Search

AKR1B1

0.39	Aldo-keto reductase

0.54	GO:0044598	doxorubicin metabolic process
0.54	GO:0044597	daunorubicin metabolic process
0.53	GO:0071475	cellular hyperosmotic salinity response
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0003091	renal water homeostasis
0.50	GO:0035809	regulation of urine volume
0.47	GO:0072001	renal system development
0.46	GO:0043066	negative regulation of apoptotic process
0.43	GO:0006061	sorbitol biosynthetic process
0.42	GO:0090420	naphthalene-containing compound metabolic process

0.55	GO:0004032	alditol:NADP+ 1-oxidoreductase activity
0.55	GO:0043795	glyceraldehyde oxidoreductase activity
0.35	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.33	GO:0009055	electron transfer activity

0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:0097454	Schwann cell microvillus
0.41	GO:0033010	paranodal junction
0.41	GO:0043220	Schmidt-Lanterman incisure
0.41	GO:0042629	mast cell granule
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle

0.55	EC:1.1.1.21	GO:0004032
0.55	KEGG:R02820	GO:0004032

sp|P07953|F261_RAT
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
Search

PFKFB1

0.90	6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1 splice variant 2

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.47	GO:0016311	dephosphorylation
0.41	GO:0033133	positive regulation of glucokinase activity
0.40	GO:0033762	response to glucagon
0.40	GO:0031100	animal organ regeneration
0.40	GO:0051591	response to cAMP
0.39	GO:0051384	response to glucocorticoid
0.39	GO:0032868	response to insulin

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.57	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042802	identical protein binding
0.41	GO:0070095	fructose-6-phosphate binding
0.38	GO:0019900	kinase binding
0.35	GO:0003968	RNA-directed 5'-3' RNA polymerase activity

0.57	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

sp|P08009|GSTM4_RAT
Glutathione S-transferase Yb-3
Search

0.42	Glutathione S-transferase

0.53	GO:0018916	nitrobenzene metabolic process
0.50	GO:0006749	glutathione metabolic process
0.48	GO:0042178	xenobiotic catabolic process
0.47	GO:0070458	cellular detoxification of nitrogen compound
0.44	GO:0035690	cellular response to drug
0.43	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.43	GO:0071415	cellular response to purine-containing compound
0.42	GO:0043651	linoleic acid metabolic process
0.42	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.42	GO:0031000	response to caffeine

0.79	GO:0004364	glutathione transferase activity
0.51	GO:0043295	glutathione binding
0.50	GO:0042802	identical protein binding
0.45	GO:0046983	protein dimerization activity
0.45	GO:0019899	enzyme binding
0.40	GO:0004602	glutathione peroxidase activity
0.39	GO:0005102	receptor binding
0.34	GO:0005496	steroid binding
0.34	GO:0016151	nickel cation binding
0.33	GO:0003735	structural constituent of ribosome

0.55	GO:0045171	intercellular bridge
0.48	GO:0005829	cytosol
0.41	GO:0016529	sarcoplasmic reticulum
0.38	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex
0.33	GO:0005840	ribosome
0.32	GO:0005886	plasma membrane

0.79

GO:0004364

sp|P08010|GSTM2_RAT
Glutathione S-transferase Mu 2
Search

0.42	Glutathione S-transferase

0.53	GO:0018916	nitrobenzene metabolic process
0.49	GO:0006749	glutathione metabolic process
0.47	GO:0042178	xenobiotic catabolic process
0.47	GO:0070458	cellular detoxification of nitrogen compound
0.43	GO:0035690	cellular response to drug
0.42	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.41	GO:0071415	cellular response to purine-containing compound
0.41	GO:0043651	linoleic acid metabolic process
0.41	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.41	GO:0031000	response to caffeine

0.78	GO:0004364	glutathione transferase activity
0.50	GO:0043295	glutathione binding
0.49	GO:0042802	identical protein binding
0.45	GO:0046983	protein dimerization activity
0.45	GO:0019899	enzyme binding
0.39	GO:0004602	glutathione peroxidase activity
0.38	GO:0005102	receptor binding
0.34	GO:0005496	steroid binding
0.34	GO:0016151	nickel cation binding
0.33	GO:0003735	structural constituent of ribosome

0.53	GO:0045171	intercellular bridge
0.46	GO:0005829	cytosol
0.40	GO:0016529	sarcoplasmic reticulum
0.37	GO:0043209	myelin sheath
0.35	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex
0.33	GO:0005840	ribosome
0.33	GO:0005886	plasma membrane

0.78

GO:0004364

sp|P08011|MGST1_RAT
Microsomal glutathione S-transferase 1
Search

MGST1

0.58	Microsomal glutathione S-transferase

0.62	GO:0071449	cellular response to lipid hydroperoxide
0.49	GO:0098869	cellular oxidant detoxification
0.43	GO:0070207	protein homotrimerization
0.41	GO:0055114	oxidation-reduction process
0.39	GO:0033327	Leydig cell differentiation
0.38	GO:0032496	response to lipopolysaccharide
0.37	GO:0010243	response to organonitrogen compound
0.36	GO:0042493	response to drug
0.36	GO:0006749	glutathione metabolic process
0.36	GO:1901685	glutathione derivative metabolic process

0.55	GO:0004364	glutathione transferase activity
0.54	GO:0004602	glutathione peroxidase activity
0.39	GO:0043295	glutathione binding
0.37	GO:0042803	protein homodimerization activity

0.45	GO:0005739	mitochondrion
0.39	GO:0031968	organelle outer membrane
0.39	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0045177	apical part of cell
0.38	GO:0031903	microbody membrane
0.38	GO:0031984	organelle subcompartment
0.38	GO:0044439	peroxisomal part
0.36	GO:0035577	azurophil granule membrane
0.35	GO:0005634	nucleus

0.55

GO:0004364

sp|P08025|IGF1_RAT
Insulin-like growth factor I
Search

IGF1

0.88	IGF-I splicing variant class 1

0.76	GO:0010469	regulation of receptor activity
0.59	GO:0045725	positive regulation of glycogen biosynthetic process
0.59	GO:0048009	insulin-like growth factor receptor signaling pathway
0.58	GO:0046326	positive regulation of glucose import
0.56	GO:1904073	regulation of trophectodermal cell proliferation
0.56	GO:2001234	negative regulation of apoptotic signaling pathway
0.55	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development
0.55	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process
0.55	GO:0010560	positive regulation of glycoprotein biosynthetic process
0.55	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.59	GO:0005159	insulin-like growth factor receptor binding
0.53	GO:0005158	insulin receptor binding
0.52	GO:0005178	integrin binding
0.35	GO:0043539	protein serine/threonine kinase activator activity
0.35	GO:0005496	steroid binding

0.73	GO:0005615	extracellular space
0.60	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.55	GO:0036454	growth factor complex
0.46	GO:0070382	exocytic vesicle
0.39	GO:0005829	cytosol
0.37	GO:0031091	platelet alpha granule
0.35	GO:0005614	interstitial matrix
0.35	GO:0034774	secretory granule lumen
0.35	GO:0043025	neuronal cell body
0.30	GO:0031224	intrinsic component of membrane

sp|P08033|CXB1_RAT
Gap junction beta-1 protein
Search

GJB1

0.64	Gap junction beta-1 protein (Fragment)

0.60	GO:0007154	cell communication
0.45	GO:0016264	gap junction assembly
0.40	GO:1905867	epididymis development
0.39	GO:0015868	purine ribonucleotide transport
0.37	GO:0023052	signaling
0.37	GO:0055085	transmembrane transport
0.36	GO:0051259	protein oligomerization
0.34	GO:0007399	nervous system development
0.34	GO:0007605	sensory perception of sound

0.52	GO:0042802	identical protein binding
0.47	GO:0046983	protein dimerization activity
0.46	GO:0005243	gap junction channel activity

0.83	GO:0005922	connexin complex
0.39	GO:0005737	cytoplasm
0.38	GO:0016328	lateral plasma membrane
0.36	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

sp|P08050|CXA1_RAT
Gap junction alpha-1 protein
Search

GJA1

0.64	Gap junction alpha-1 protein (Fragment)

0.80	GO:0007507	heart development
0.75	GO:0007267	cell-cell signaling
0.55	GO:0010644	cell communication by electrical coupling
0.55	GO:0055085	transmembrane transport
0.52	GO:0060156	milk ejection reflex
0.51	GO:0010643	cell communication by chemical coupling
0.50	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization
0.50	GO:0030308	negative regulation of cell growth
0.50	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.50	GO:0002070	epithelial cell maturation

0.57	GO:0022857	transmembrane transporter activity
0.49	GO:0097110	scaffold protein binding
0.48	GO:1990782	protein tyrosine kinase binding
0.48	GO:0048487	beta-tubulin binding
0.44	GO:0004871	signal transducer activity
0.44	GO:0005102	receptor binding
0.39	GO:0030165	PDZ domain binding
0.38	GO:0071253	connexin binding
0.38	GO:0017124	SH3 domain binding
0.38	GO:0097718	disordered domain specific binding

0.84	GO:0005922	connexin complex
0.56	GO:0014704	intercalated disc
0.48	GO:0016328	lateral plasma membrane
0.47	GO:0005913	cell-cell adherens junction
0.47	GO:0016324	apical plasma membrane
0.47	GO:0005654	nucleoplasm
0.47	GO:0043292	contractile fiber
0.46	GO:0005882	intermediate filament
0.44	GO:0012505	endomembrane system
0.43	GO:0005739	mitochondrion

sp|P08081|CLCA_RAT
Clathrin light chain A
Search

CLTA

0.68	Clathrin light chain A

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.53	GO:0048268	clathrin coat assembly
0.45	GO:0098657	import into cell
0.37	GO:0051301	cell division
0.37	GO:0007049	cell cycle
0.37	GO:0032802	low-density lipoprotein particle receptor catabolic process
0.36	GO:0034383	low-density lipoprotein particle clearance
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0007018	microtubule-based movement

0.62	GO:0005198	structural molecule activity
0.59	GO:0032050	clathrin heavy chain binding
0.39	GO:0042277	peptide binding
0.38	GO:0032403	protein complex binding
0.38	GO:0051020	GTPase binding

0.83	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.82	GO:0030132	clathrin coat of coated pit
0.54	GO:0071439	clathrin complex
0.40	GO:0030672	synaptic vesicle membrane
0.40	GO:0099631	postsynaptic endocytic zone cytoplasmic component
0.39	GO:0005819	spindle
0.38	GO:0045334	clathrin-coated endocytic vesicle
0.37	GO:0036020	endolysosome membrane
0.37	GO:0005802	trans-Golgi network
0.36	GO:0030666	endocytic vesicle membrane

sp|P08082|CLCB_RAT
Clathrin light chain B
Search

CLTB

0.67	Clathrin light chain B

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.45	GO:0098657	import into cell
0.41	GO:0048268	clathrin coat assembly
0.36	GO:0036465	synaptic vesicle recycling
0.35	GO:0097480	establishment of synaptic vesicle localization
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.35	GO:0061024	membrane organization
0.35	GO:0016050	vesicle organization

0.62	GO:0005198	structural molecule activity
0.53	GO:0032050	clathrin heavy chain binding
0.38	GO:0042277	peptide binding
0.35	GO:0005326	neurotransmitter transporter activity
0.34	GO:0000287	magnesium ion binding

0.83	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.82	GO:0030132	clathrin coat of coated pit
0.56	GO:0060170	ciliary membrane
0.53	GO:0005802	trans-Golgi network
0.48	GO:0005829	cytosol
0.41	GO:0071439	clathrin complex
0.35	GO:0045334	clathrin-coated endocytic vesicle
0.35	GO:0098793	presynapse
0.34	GO:0005819	spindle
0.33	GO:0019028	viral capsid

sp|P08104|SCN3A_RAT
Sodium channel protein type 3 subunit alpha
Search

SCN3A

0.56	Sodium channel protein type 3 subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0035725	sodium ion transmembrane transport
0.50	GO:0019228	neuronal action potential
0.50	GO:0086010	membrane depolarization during action potential
0.43	GO:0046684	response to pyrethroid
0.41	GO:0071236	cellular response to antibiotic
0.41	GO:0019233	sensory perception of pain
0.39	GO:0009611	response to wounding
0.38	GO:0007399	nervous system development

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.72	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.40	GO:0031402	sodium ion binding
0.39	GO:0005516	calmodulin binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.39	GO:0005737	cytoplasm

sp|P08154|EGR1_RAT
Early growth response protein 1
Search

EGR1

0.82	Early growth response protein 1-A

0.60	GO:0050722	regulation of interleukin-1 beta biosynthetic process
0.60	GO:0045362	positive regulation of interleukin-1 biosynthetic process
0.60	GO:2000182	regulation of progesterone biosynthetic process
0.60	GO:0098758	response to interleukin-8
0.59	GO:0044849	estrous cycle
0.58	GO:0045080	positive regulation of chemokine biosynthetic process
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0046886	positive regulation of hormone biosynthetic process
0.57	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.57	GO:0002931	response to ischemia

0.60	GO:0044729	hemi-methylated DNA-binding
0.58	GO:0010385	double-stranded methylated DNA binding
0.57	GO:1990841	promoter-specific chromatin binding
0.56	GO:0035035	histone acetyltransferase binding
0.54	GO:0046872	metal ion binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.35	GO:0001046	core promoter sequence-specific DNA binding
0.34	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm

sp|P08289|PPBT_RAT
Alkaline phosphatase, tissue-nonspecific isozyme
Search

ALPL

0.47	Alkaline phosphatase, tissue-nonspecific isozyme

0.68	GO:0016311	dephosphorylation
0.57	GO:0033280	response to vitamin D
0.57	GO:0001958	endochondral ossification
0.51	GO:0071407	cellular response to organic cyclic compound
0.51	GO:0003006	developmental process involved in reproduction
0.50	GO:0046677	response to antibiotic
0.44	GO:0009612	response to mechanical stimulus
0.42	GO:0071529	cementum mineralization
0.40	GO:0051384	response to glucocorticoid
0.39	GO:0032496	response to lipopolysaccharide

0.81	GO:0004035	alkaline phosphatase activity
0.43	GO:0016462	pyrophosphatase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0002020	protease binding

0.58	GO:0065010	extracellular membrane-bounded organelle
0.51	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005886	plasma membrane
0.41	GO:0031225	anchored component of membrane
0.38	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.81

EC:3.1.3.1

GO:0004035

sp|P08290|ASGR2_RAT
Asialoglycoprotein receptor 2
Search

0.96	Asialoglycoprotein receptor 2

0.57	GO:0055088	lipid homeostasis
0.56	GO:0031647	regulation of protein stability
0.53	GO:0009100	glycoprotein metabolic process
0.50	GO:0031668	cellular response to extracellular stimulus
0.44	GO:0030282	bone mineralization
0.44	GO:0006897	endocytosis
0.39	GO:0018196	peptidyl-asparagine modification
0.38	GO:0043413	macromolecule glycosylation
0.36	GO:1901137	carbohydrate derivative biosynthetic process
0.35	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.52	GO:0042803	protein homodimerization activity
0.46	GO:0004873	asialoglycoprotein receptor activity
0.35	GO:0046872	metal ion binding

0.35	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P08413|KCC2B_RAT
Calcium/calmodulin-dependent protein kinase type II subunit beta
Search

CAMK2B

0.92	Calmodulin dependent protein kinase II beta subunit

0.63	GO:0006468	protein phosphorylation
0.46	GO:0018210	peptidyl-threonine modification
0.45	GO:0018209	peptidyl-serine modification
0.42	GO:0007399	nervous system development
0.42	GO:0090129	positive regulation of synapse maturation
0.42	GO:0060999	positive regulation of dendritic spine development
0.42	GO:0030154	cell differentiation
0.41	GO:0099175	regulation of postsynapse organization
0.41	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.40	GO:0031346	positive regulation of cell projection organization

0.81	GO:0004683	calmodulin-dependent protein kinase activity
0.78	GO:0005516	calmodulin binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.48	GO:0042803	protein homodimerization activity
0.36	GO:0043274	phospholipase binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.43	GO:0043005	neuron projection
0.41	GO:0033017	sarcoplasmic reticulum membrane
0.39	GO:0005815	microtubule organizing center
0.38	GO:0051233	spindle midzone
0.38	GO:0014069	postsynaptic density
0.37	GO:0005829	cytosol
0.36	GO:0043204	perikaryon
0.35	GO:0030666	endocytic vesicle membrane
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005654	nucleoplasm

0.81

EC:2.7.11.17

GO:0004683

sp|P08424|RENI_RAT
Renin
Search

REN

0.97

Pro-renin

0.61	GO:0006508	proteolysis
0.59	GO:0002002	regulation of angiotensin levels in blood
0.58	GO:0002018	renin-angiotensin regulation of aldosterone production
0.57	GO:0042756	drinking behavior
0.54	GO:0001823	mesonephros development
0.54	GO:0008584	male gonad development
0.53	GO:0042445	hormone metabolic process
0.53	GO:0048469	cell maturation
0.51	GO:0051604	protein maturation
0.51	GO:0043408	regulation of MAPK cascade

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.48	GO:0005102	receptor binding
0.34	GO:0004983	neuropeptide Y receptor activity

0.52	GO:0045177	apical part of cell
0.49	GO:0005615	extracellular space
0.37	GO:0005622	intracellular
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P08426|TRY3_RAT
Cationic trypsin-3
Search

0.46	Pancreatic anionic trypsinogen

0.61	GO:0006508	proteolysis
0.53	GO:0007586	digestion
0.39	GO:0030574	collagen catabolic process
0.38	GO:0043542	endothelial cell migration
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.37	GO:0035094	response to nicotine
0.36	GO:0022617	extracellular matrix disassembly
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0019730	antimicrobial humoral response

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005509	calcium ion binding
0.35	GO:0097655	serpin family protein binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0004222	metalloendopeptidase activity

0.51	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0030141	secretory granule
0.35	GO:0097180	serine protease inhibitor complex
0.35	GO:0044433	cytoplasmic vesicle part
0.34	GO:0005766	primary lysosome
0.34	GO:0031983	vesicle lumen
0.34	GO:0005775	vacuolar lumen
0.33	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P08427|SFTPA_RAT
Pulmonary surfactant-associated protein A
Search

SFTPA1

0.95	Pulmonary surfactant-associated protein A

0.58	GO:0007585	respiratory gaseous exchange
0.51	GO:0008228	opsonization
0.44	GO:0033189	response to vitamin A
0.44	GO:0048518	positive regulation of biological process
0.44	GO:0071732	cellular response to nitric oxide
0.44	GO:0055093	response to hyperoxia
0.44	GO:0070741	response to interleukin-6
0.43	GO:0070849	response to epidermal growth factor
0.43	GO:0071260	cellular response to mechanical stimulus
0.43	GO:0050764	regulation of phagocytosis

0.51	GO:0030246	carbohydrate binding
0.48	GO:0005201	extracellular matrix structural constituent
0.41	GO:0046872	metal ion binding
0.41	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0005515	protein binding
0.37	GO:0005319	lipid transporter activity
0.35	GO:0004478	methionine adenosyltransferase activity
0.35	GO:0036094	small molecule binding
0.35	GO:0044877	macromolecular complex binding
0.33	GO:0042302	structural constituent of cuticle

0.71	GO:0005581	collagen trimer
0.58	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0005615	extracellular space
0.50	GO:0044420	extracellular matrix component
0.43	GO:0005771	multivesicular body
0.42	GO:0005783	endoplasmic reticulum
0.42	GO:0042599	lamellar body
0.41	GO:0045334	clathrin-coated endocytic vesicle
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment

0.35

EC:2.5.1.6

GO:0004478

sp|P08430|UD16_RAT
UDP-glucuronosyltransferase 1-6
Search

0.54	UDP-glucuronosyltransferase

0.61	GO:0052695	cellular glucuronidation
0.56	GO:0009812	flavonoid metabolic process
0.52	GO:0006805	xenobiotic metabolic process
0.47	GO:2001030	negative regulation of cellular glucuronidation
0.46	GO:1904223	regulation of glucuronosyltransferase activity
0.44	GO:0043086	negative regulation of catalytic activity
0.43	GO:0045922	negative regulation of fatty acid metabolic process
0.42	GO:0001889	liver development
0.41	GO:0042440	pigment metabolic process
0.41	GO:0071385	cellular response to glucocorticoid stimulus

0.81	GO:0015020	glucuronosyltransferase activity
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.50	GO:0001972	retinoic acid binding
0.47	GO:0019899	enzyme binding
0.45	GO:0005496	steroid binding
0.44	GO:0004857	enzyme inhibitor activity
0.41	GO:0005504	fatty acid binding
0.35	GO:0008144	drug binding
0.34	GO:0032403	protein complex binding

0.50	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0070062	extracellular exosome
0.38	GO:0043234	protein complex
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

0.81

GO:0015020

sp|P08435|TKNK_RAT
Tachykinin-3
Search

TAC3

0.97	Neurokinin B

0.85	GO:0007217	tachykinin receptor signaling pathway
0.47	GO:0007218	neuropeptide signaling pathway
0.41	GO:0007018	microtubule-based movement
0.41	GO:0043278	response to morphine
0.40	GO:0045777	positive regulation of blood pressure
0.38	GO:1902093	positive regulation of flagellated sperm motility
0.38	GO:0007565	female pregnancy

0.41	GO:0003777	microtubule motor activity
0.41	GO:0008017	microtubule binding
0.41	GO:0003779	actin binding
0.40	GO:0031836	neuromedin K receptor binding
0.40	GO:0031837	substance K receptor binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005576	extracellular region
0.41	GO:0016459	myosin complex
0.39	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P08460|NID1_RAT
Nidogen-1 (Fragment)
Search

0.82	GO:0007160	cell-matrix adhesion
0.60	GO:0032836	glomerular basement membrane development
0.57	GO:0010811	positive regulation of cell-substrate adhesion
0.36	GO:0022617	extracellular matrix disassembly
0.36	GO:0071711	basement membrane organization
0.32	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.67	GO:0005509	calcium ion binding
0.61	GO:0043237	laminin-1 binding
0.60	GO:0043394	proteoglycan binding
0.58	GO:0005518	collagen binding
0.32	GO:0008146	sulfotransferase activity

0.59	GO:0005605	basal lamina
0.52	GO:0005615	extracellular space
0.43	GO:0071944	cell periphery
0.38	GO:1903561	extracellular vesicle
0.33	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008146

sp|P08461|ODP2_RAT
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
Search

0.40	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

0.67	GO:0006090	pyruvate metabolic process
0.35	GO:0006006	glucose metabolic process
0.35	GO:0006099	tricarboxylic acid cycle
0.30	GO:0051188	cofactor biosynthetic process
0.30	GO:0035383	thioester metabolic process
0.30	GO:0032501	multicellular organismal process
0.30	GO:1901576	organic substance biosynthetic process
0.30	GO:0006732	coenzyme metabolic process
0.30	GO:0044272	sulfur compound biosynthetic process
0.30	GO:0006793	phosphorus metabolic process

0.79	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity
0.30	GO:0005515	protein binding
0.30	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors
0.30	GO:1901363	heterocyclic compound binding
0.30	GO:0036094	small molecule binding
0.30	GO:0097159	organic cyclic compound binding

0.78	GO:0045254	pyruvate dehydrogenase complex
0.72	GO:0005759	mitochondrial matrix
0.30	GO:0043209	myelin sheath

0.79

EC:2.3.1.12

GO:0004742

sp|P08462|GRPB_RAT
Submandibular gland secretory Glx-rich protein CB
Search

0.65	GO:0031214	biomineral tissue development
0.56	GO:0001895	retina homeostasis
0.43	GO:0030216	keratinocyte differentiation
0.38	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0031297	replication fork processing
0.38	GO:0060548	negative regulation of cell death
0.38	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:0043666	regulation of phosphoprotein phosphatase activity
0.37	GO:0006801	superoxide metabolic process
0.36	GO:0006470	protein dephosphorylation

0.58	GO:0046848	hydroxyapatite binding
0.39	GO:0016307	phosphatidylinositol phosphate kinase activity
0.38	GO:0005544	calcium-dependent phospholipid binding
0.37	GO:0030983	mismatched DNA binding
0.37	GO:0005515	protein binding
0.37	GO:0019888	protein phosphatase regulator activity
0.37	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0032559	adenyl ribonucleotide binding

0.57	GO:0005576	extracellular region
0.43	GO:0001533	cornified envelope
0.38	GO:0030289	protein phosphatase 4 complex
0.37	GO:0005856	cytoskeleton
0.36	GO:0005654	nucleoplasm
0.35	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.39

GO:0016307

sp|P08482|ACM1_RAT
Muscarinic acetylcholine receptor M1
Search

CHRM1

0.77	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.82	GO:0022600	digestive system process
0.79	GO:0032941	secretion by tissue
0.77	GO:0007589	body fluid secretion
0.68	GO:0050890	cognition
0.64	GO:0040012	regulation of locomotion
0.60	GO:0007603	phototransduction, visible light
0.60	GO:0006940	regulation of smooth muscle contraction
0.59	GO:0009649	entrainment of circadian clock
0.57	GO:0043270	positive regulation of ion transport

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.37	GO:0004435	phosphatidylinositol phospholipase C activity
0.35	GO:0008144	drug binding
0.34	GO:0016934	extracellularly glycine-gated chloride channel activity
0.34	GO:0042562	hormone binding
0.34	GO:0070405	ammonium ion binding
0.34	GO:0042165	neurotransmitter binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.42	GO:0043679	axon terminus
0.41	GO:0014069	postsynaptic density
0.41	GO:0030425	dendrite
0.34	GO:0016323	basolateral plasma membrane

0.37	EC:3.1.4.11	GO:0004435
0.37	KEGG:R03435	GO:0004435

sp|P08483|ACM3_RAT
Muscarinic acetylcholine receptor M3
Search

CHRM3

0.81	Muscarinic acetylcholine receptor

0.85	GO:0046541	saliva secretion
0.84	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.83	GO:0045987	positive regulation of smooth muscle contraction
0.51	GO:0003056	regulation of vascular smooth muscle contraction
0.50	GO:0007271	synaptic transmission, cholinergic
0.50	GO:0001696	gastric acid secretion
0.49	GO:0006939	smooth muscle contraction
0.49	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.49	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.44	GO:0015872	dopamine transport

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.46	GO:0042166	acetylcholine binding
0.35	GO:0005515	protein binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0016934	extracellularly glycine-gated chloride channel activity
0.34	GO:0098772	molecular function regulator

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.66	GO:0005887	integral component of plasma membrane
0.43	GO:0016323	basolateral plasma membrane
0.41	GO:0043679	axon terminus
0.41	GO:0032279	asymmetric synapse
0.40	GO:0030425	dendrite

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P08485|ACM4_RAT
Muscarinic acetylcholine receptor M4
Search

CHRM4

0.82	Muscarinic acetylcholine receptor

0.84	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.70	GO:0040012	regulation of locomotion
0.60	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.56	GO:0008016	regulation of heart contraction
0.51	GO:0007271	synaptic transmission, cholinergic
0.50	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.46	GO:0009615	response to virus
0.43	GO:0006940	regulation of smooth muscle contraction
0.37	GO:1903523	negative regulation of blood circulation
0.35	GO:0007194	negative regulation of adenylate cyclase activity

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.51	GO:1990763	arrestin family protein binding
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0008144	drug binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.66	GO:0005887	integral component of plasma membrane
0.38	GO:0043679	axon terminus
0.38	GO:0032279	asymmetric synapse
0.38	GO:0032280	symmetric synapse
0.38	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.35	GO:0042383	sarcolemma
0.35	GO:0099572	postsynaptic specialization

sp|P08494|MGP_RAT
Matrix Gla protein
Search

MGP

0.89	Matrix Gla protein (Fragment)

0.74	GO:0030500	regulation of bone mineralization
0.49	GO:0051216	cartilage development
0.48	GO:0001503	ossification
0.45	GO:0030154	cell differentiation
0.37	GO:0009653	anatomical structure morphogenesis
0.37	GO:0051384	response to glucocorticoid
0.37	GO:0051592	response to calcium ion
0.37	GO:0030324	lung development
0.37	GO:0009612	response to mechanical stimulus
0.37	GO:0007584	response to nutrient

0.70	GO:0005509	calcium ion binding
0.49	GO:0005201	extracellular matrix structural constituent
0.39	GO:0008147	structural constituent of bone
0.37	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.39	GO:0070062	extracellular exosome
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P08503|ACADM_RAT
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADM

0.93	Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight chain

0.75	GO:0006635	fatty acid beta-oxidation
0.57	GO:0019254	carnitine metabolic process, CoA-linked
0.55	GO:0051791	medium-chain fatty acid metabolic process
0.53	GO:0055007	cardiac muscle cell differentiation
0.53	GO:0001889	liver development
0.53	GO:0006111	regulation of gluconeogenesis
0.51	GO:0009409	response to cold
0.50	GO:0009791	post-embryonic development
0.50	GO:0042594	response to starvation
0.49	GO:0005978	glycogen biosynthetic process

0.86	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding

0.59	GO:0005739	mitochondrion
0.52	GO:0016607	nuclear speck

0.86

EC:1.3.99

GO:0070991

sp|P08516|CP4AA_RAT
Cytochrome P450 4A10
Search

0.97	Fatty acid omega-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0006690	icosanoid metabolic process
0.45	GO:0033559	unsaturated fatty acid metabolic process
0.44	GO:0001676	long-chain fatty acid metabolic process
0.42	GO:1901569	fatty acid derivative catabolic process
0.41	GO:0048252	lauric acid metabolic process
0.40	GO:0009062	fatty acid catabolic process
0.40	GO:1901616	organic hydroxy compound catabolic process
0.39	GO:0001822	kidney development
0.38	GO:1901570	fatty acid derivative biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.64	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0103002	16-hydroxypalmitate dehydrogenase activity
0.35	GO:0050544	arachidonic acid binding
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0016324	apical plasma membrane
0.40	GO:0005615	extracellular space
0.39	GO:0031090	organelle membrane
0.35	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P08523|OMP_RAT
Olfactory marker protein
Search

OMP

0.97	Olfactory marker protein a

0.76	GO:0007608	sensory perception of smell
0.61	GO:0007165	signal transduction
0.45	GO:0098916	anterograde trans-synaptic signaling
0.44	GO:0022008	neurogenesis
0.38	GO:0006508	proteolysis

0.64	GO:0004871	signal transducer activity
0.44	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.37	GO:0042277	peptide binding
0.35	GO:0005515	protein binding

0.48	GO:0043025	neuronal cell body
0.48	GO:0030424	axon
0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus

sp|P08541|UD2B2_RAT
UDP-glucuronosyltransferase 2B2
Search

0.54	UDP-glucuronosyltransferase

0.50	GO:0052695	cellular glucuronidation
0.39	GO:0008209	androgen metabolic process
0.38	GO:0071394	cellular response to testosterone stimulus
0.38	GO:0071361	cellular response to ethanol
0.38	GO:0071378	cellular response to growth hormone stimulus
0.38	GO:0071385	cellular response to glucocorticoid stimulus
0.37	GO:0070980	biphenyl catabolic process
0.37	GO:0032496	response to lipopolysaccharide
0.32	GO:0017144	drug metabolic process

0.80	GO:0015020	glucuronosyltransferase activity
0.41	GO:0001972	retinoic acid binding

0.44	GO:0005783	endoplasmic reticulum
0.44	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0005740	mitochondrial envelope
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0015020

sp|P08542|UDB17_RAT
UDP-glucuronosyltransferase 2B17
Search

0.53	UDP-glucuronosyltransferase

0.49	GO:0052695	cellular glucuronidation
0.39	GO:0008209	androgen metabolic process
0.38	GO:0071394	cellular response to testosterone stimulus
0.38	GO:0071361	cellular response to ethanol
0.38	GO:0071378	cellular response to growth hormone stimulus
0.38	GO:0071385	cellular response to glucocorticoid stimulus
0.37	GO:0032496	response to lipopolysaccharide
0.37	GO:0070980	biphenyl catabolic process
0.32	GO:0017144	drug metabolic process

0.80	GO:0015020	glucuronosyltransferase activity
0.41	GO:0001972	retinoic acid binding

0.44	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0005740	mitochondrial envelope
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0015020

sp|P08568|GRPA_RAT
Submandibular gland secretory Glx-rich protein CA
Search

0.66	GO:0031214	biomineral tissue development
0.55	GO:0001895	retina homeostasis
0.43	GO:0030216	keratinocyte differentiation
0.41	GO:0031297	replication fork processing
0.39	GO:0006974	cellular response to DNA damage stimulus
0.38	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0060548	negative regulation of cell death
0.37	GO:0045859	regulation of protein kinase activity
0.37	GO:0006801	superoxide metabolic process
0.35	GO:0006518	peptide metabolic process

0.61	GO:0046848	hydroxyapatite binding
0.39	GO:0016307	phosphatidylinositol phosphate kinase activity
0.39	GO:0005515	protein binding
0.39	GO:0005544	calcium-dependent phospholipid binding
0.38	GO:0030983	mismatched DNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005576	extracellular region
0.43	GO:0001533	cornified envelope
0.38	GO:0031588	nucleotide-activated protein kinase complex
0.38	GO:0005654	nucleoplasm
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.39

GO:0016307

sp|P08592|A4_RAT
Amyloid beta A4 protein
Search

APP

0.93	Testicular tissue protein Li 2

0.74	GO:0007399	nervous system development
0.71	GO:0010951	negative regulation of endopeptidase activity
0.59	GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis
0.58	GO:1905908	positive regulation of amyloid fibril formation
0.58	GO:0032640	tumor necrosis factor production
0.58	GO:0150003	regulation of spontaneous synaptic transmission
0.57	GO:0007176	regulation of epidermal growth factor-activated receptor activity
0.57	GO:1903980	positive regulation of microglial cell activation
0.57	GO:1990535	neuron projection maintenance
0.57	GO:1900272	negative regulation of long-term synaptic potentiation

0.81	GO:0008201	heparin binding
0.73	GO:0004867	serine-type endopeptidase inhibitor activity
0.58	GO:0051425	PTB domain binding
0.57	GO:0046914	transition metal ion binding
0.49	GO:0042802	identical protein binding
0.49	GO:0005102	receptor binding
0.48	GO:0019899	enzyme binding
0.42	GO:0003677	DNA binding
0.41	GO:0016504	peptidase activator activity
0.37	GO:0097645	amylin binding

0.56	GO:0035253	ciliary rootlet
0.56	GO:0005790	smooth endoplasmic reticulum
0.56	GO:0005641	nuclear envelope lumen
0.55	GO:0043198	dendritic shaft
0.54	GO:0031594	neuromuscular junction
0.54	GO:0043197	dendritic spine
0.54	GO:0051233	spindle midzone
0.54	GO:0030424	axon
0.52	GO:0045177	apical part of cell
0.52	GO:0098589	membrane region

0.34

GO:0008233

sp|P08635|SAST_RAT
S-acyl fatty acid synthase thioesterase, medium chain
Search

OLAH

0.85	S-acyl fatty acid synthase thioesterase medium chain

0.49	GO:0009058	biosynthetic process
0.41	GO:0006629	lipid metabolic process
0.37	GO:0032787	monocarboxylic acid metabolic process
0.34	GO:0071770	DIM/DIP cell wall layer assembly
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0052562	negative regulation by symbiont of host immune response

0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.40	GO:0004312	fatty acid synthase activity
0.38	GO:0031177	phosphopantetheine binding
0.34	GO:0016874	ligase activity
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.32	GO:0009507	chloroplast
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.61

EC:3.1

GO:0016788

sp|P08644|RASK_RAT
GTPase KRas
Search

KRAS

0.90	-Ha-ras Harvey rat sarcoma viral oncogene homolog b

0.61	GO:0007165	signal transduction
0.56	GO:0038002	endocrine signaling
0.55	GO:0021897	forebrain astrocyte development
0.54	GO:0035022	positive regulation of Rac protein signal transduction
0.53	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.53	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.52	GO:0048873	homeostasis of number of cells within a tissue
0.52	GO:0032228	regulation of synaptic transmission, GABAergic
0.52	GO:0008542	visual learning
0.52	GO:0008284	positive regulation of cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.48	GO:0032403	protein complex binding
0.41	GO:0019002	GMP binding
0.40	GO:0030275	LRR domain binding
0.40	GO:0019003	GDP binding
0.36	GO:0042802	identical protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0005737	cytoplasm
0.39	GO:0098857	membrane microdomain
0.36	GO:0005925	focal adhesion
0.35	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0020002	host cell plasma membrane
0.33	GO:0012505	endomembrane system

sp|P08649|CO4_RAT
Complement C4
Search

0.95	Complement component 4

0.76	GO:0006956	complement activation
0.74	GO:0010951	negative regulation of endopeptidase activity
0.72	GO:0006954	inflammatory response
0.58	GO:0016064	immunoglobulin mediated immune response
0.43	GO:2000427	positive regulation of apoptotic cell clearance
0.42	GO:0045087	innate immune response
0.40	GO:0032490	detection of molecule of bacterial origin
0.39	GO:0030449	regulation of complement activation
0.37	GO:0008228	opsonization
0.36	GO:0043687	post-translational protein modification

0.75	GO:0004866	endopeptidase inhibitor activity
0.44	GO:0001848	complement binding
0.43	GO:0001846	opsonin binding
0.38	GO:0030246	carbohydrate binding
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding

0.72	GO:0005615	extracellular space
0.44	GO:0030425	dendrite
0.44	GO:0030424	axon
0.43	GO:0045202	synapse
0.41	GO:0030054	cell junction
0.41	GO:0043025	neuronal cell body
0.40	GO:1903561	extracellular vesicle
0.37	GO:0044217	other organism part
0.36	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005886	plasma membrane

0.36

GO:0004252

sp|P08650|CO5_RAT
Complement C5 (Fragment)
Search

0.95	Complement C5a anaphylatoxin

0.74	GO:0006956	complement activation
0.73	GO:0010951	negative regulation of endopeptidase activity
0.73	GO:0010760	negative regulation of macrophage chemotaxis
0.72	GO:0090197	positive regulation of chemokine secretion
0.71	GO:0006954	inflammatory response
0.71	GO:0010575	positive regulation of vascular endothelial growth factor production
0.66	GO:0045766	positive regulation of angiogenesis
0.65	GO:0001701	in utero embryonic development
0.49	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.46	GO:0045087	innate immune response

0.74	GO:0004866	endopeptidase inhibitor activity
0.42	GO:0031714	C5a anaphylatoxin chemotactic receptor binding
0.38	GO:0008009	chemokine activity

0.69	GO:0005615	extracellular space
0.69	GO:0005579	membrane attack complex
0.42	GO:1903561	extracellular vesicle

sp|P08661|MBL2_RAT
Mannose-binding protein C
Search

MBL2

0.87	Pulmonary surfactant-associated protein A

0.80	GO:0001867	complement activation, lectin pathway
0.53	GO:0044130	negative regulation of growth of symbiont in host
0.51	GO:0050830	defense response to Gram-positive bacterium
0.50	GO:0048525	negative regulation of viral process
0.50	GO:0006958	complement activation, classical pathway
0.48	GO:0051873	killing by host of symbiont cells
0.47	GO:0050766	positive regulation of phagocytosis
0.39	GO:0007155	cell adhesion
0.38	GO:0030903	notochord development
0.38	GO:0060174	limb bud formation

0.78	GO:0005537	mannose binding
0.51	GO:0048306	calcium-dependent protein binding
0.47	GO:0005201	extracellular matrix structural constituent
0.47	GO:0005102	receptor binding
0.44	GO:0005509	calcium ion binding
0.41	GO:0005540	hyaluronic acid binding
0.38	GO:0048407	platelet-derived growth factor binding
0.37	GO:0042802	identical protein binding
0.37	GO:0002020	protease binding
0.37	GO:0070273	phosphatidylinositol-4-phosphate binding

0.71	GO:0005581	collagen trimer
0.49	GO:0005576	extracellular region
0.36	GO:0099081	supramolecular polymer
0.34	GO:0009986	cell surface
0.33	GO:0005737	cytoplasm
0.32	GO:0031594	neuromuscular junction
0.32	GO:0019867	outer membrane
0.32	GO:0012505	endomembrane system
0.32	GO:0070013	intracellular organelle lumen
0.31	GO:0044446	intracellular organelle part

0.34

GO:0004252

sp|P08683|CP2CB_RAT
Cytochrome P450 2C11
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.58	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0042738	exogenous drug catabolic process
0.45	GO:0043651	linoleic acid metabolic process
0.45	GO:0016098	monoterpenoid metabolic process
0.44	GO:0008202	steroid metabolic process
0.43	GO:0070988	demethylation
0.43	GO:0002933	lipid hydroxylation
0.38	GO:0006805	xenobiotic metabolic process
0.38	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.49	GO:0034875	caffeine oxidase activity
0.38	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P08689|SHBG_RAT
Sex hormone-binding globulin
Search

SHBG

0.96	Sex hormone-binding globulin

0.60

GO:0007285

primary spermatocyte growth

0.83	GO:0005496	steroid binding
0.60	GO:0005497	androgen binding
0.49	GO:0005515	protein binding

0.65	GO:0005576	extracellular region
0.55	GO:0031982	vesicle

sp|P08699|LEG3_RAT
Galectin-3
Search

LGALS3

0.64

Galectin

0.60	GO:0048246	macrophage chemotaxis
0.60	GO:0048245	eosinophil chemotaxis
0.59	GO:0090280	positive regulation of calcium ion import
0.59	GO:0002548	monocyte chemotaxis
0.59	GO:0071677	positive regulation of mononuclear cell migration
0.59	GO:0070232	regulation of T cell apoptotic process
0.59	GO:0045806	negative regulation of endocytosis
0.58	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.58	GO:0030593	neutrophil chemotaxis
0.58	GO:0050918	positive chemotaxis

0.69	GO:0030246	carbohydrate binding
0.62	GO:0019863	IgE binding
0.59	GO:0042056	chemoattractant activity
0.59	GO:0043236	laminin binding
0.38	GO:0050785	advanced glycation end-product receptor activity
0.38	GO:0034988	Fc-gamma receptor I complex binding
0.35	GO:0003723	RNA binding
0.34	GO:0005543	phospholipid binding
0.34	GO:0043130	ubiquitin binding
0.33	GO:0005509	calcium ion binding

0.58	GO:0001772	immunological synapse
0.52	GO:0031012	extracellular matrix
0.46	GO:0005634	nucleus
0.46	GO:0031966	mitochondrial membrane
0.46	GO:0019866	organelle inner membrane
0.40	GO:0097386	glial cell projection
0.38	GO:0009897	external side of plasma membrane
0.38	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.38	GO:0030529	intracellular ribonucleoprotein complex

0.33

GO:0004252

sp|P08721|OSTP_RAT
Osteopontin
Search

SPP1

0.95	Secreted phosphoprotein 1

0.83	GO:0001503	ossification
0.72	GO:0007155	cell adhesion
0.67	GO:0006710	androgen catabolic process
0.67	GO:2000866	positive regulation of estradiol secretion
0.66	GO:0071394	cellular response to testosterone stimulus
0.64	GO:0033280	response to vitamin D
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.53	GO:0046852	positive regulation of bone remodeling
0.53	GO:0045124	regulation of bone resorption
0.51	GO:0032846	positive regulation of homeostatic process

0.50	GO:0050840	extracellular matrix binding
0.45	GO:0005125	cytokine activity
0.33	GO:0016301	kinase activity

0.56	GO:0005615	extracellular space
0.56	GO:0005794	Golgi apparatus
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0045177	apical part of cell
0.41	GO:1903561	extracellular vesicle
0.39	GO:0042995	cell projection
0.36	GO:0005788	endoplasmic reticulum lumen

sp|P08723|SPBP_RAT
Prostatic spermine-binding protein
Search

SBP

0.82	prostatic spermine-binding protein-like

0.41	GO:0001895	retina homeostasis
0.37	GO:0030001	metal ion transport
0.36	GO:0006396	RNA processing
0.36	GO:0000055	ribosomal large subunit export from nucleus
0.36	GO:0019538	protein metabolic process
0.35	GO:0042273	ribosomal large subunit biogenesis
0.35	GO:0055114	oxidation-reduction process
0.35	GO:0030036	actin cytoskeleton organization
0.35	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0051716	cellular response to stimulus

0.44	GO:0019808	polyamine binding
0.44	GO:0030246	carbohydrate binding
0.41	GO:0003723	RNA binding
0.38	GO:0005509	calcium ion binding
0.36	GO:0008146	sulfotransferase activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0016787	hydrolase activity
0.35	GO:0016491	oxidoreductase activity
0.35	GO:0005525	GTP binding
0.34	GO:0016209	antioxidant activity

0.40	GO:0005576	extracellular region
0.39	GO:0043227	membrane-bounded organelle
0.36	GO:0043229	intracellular organelle
0.36	GO:0019867	outer membrane
0.36	GO:0044462	external encapsulating structure part
0.35	GO:0030313	cell envelope
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0030688	preribosome, small subunit precursor
0.35	GO:1990234	transferase complex
0.35	GO:0044422	organelle part

0.36

GO:0008146

sp|P08733|MLRV_RAT
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
Search

MYL2

0.96	Cardiac ventricular myosin light chain-2

0.59	GO:0098735	positive regulation of the force of heart contraction
0.58	GO:0042694	muscle cell fate specification
0.57	GO:0055003	cardiac myofibril assembly
0.55	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.55	GO:0060047	heart contraction
0.55	GO:0048747	muscle fiber development
0.54	GO:0006941	striated muscle contraction
0.54	GO:0030308	negative regulation of cell growth
0.52	GO:0009791	post-embryonic development
0.36	GO:0061049	cell growth involved in cardiac muscle cell development

0.69	GO:0005509	calcium ion binding
0.55	GO:0003785	actin monomer binding
0.35	GO:0032036	myosin heavy chain binding
0.35	GO:0008307	structural constituent of muscle

0.57	GO:0097512	cardiac myofibril
0.51	GO:0015629	actin cytoskeleton
0.40	GO:0031672	A band
0.38	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.35	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P08753|GNAI3_RAT
Guanine nucleotide-binding protein G(k) subunit alpha
Search

GNAI3

0.78	Guanine nucleotide binding protein alpha inhibiting 3

0.80	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.44	GO:0007212	dopamine receptor signaling pathway
0.43	GO:1904778	positive regulation of protein localization to cell cortex
0.43	GO:0016239	positive regulation of macroautophagy
0.42	GO:0051301	cell division
0.42	GO:0046039	GTP metabolic process
0.42	GO:0060236	regulation of mitotic spindle organization
0.41	GO:1904321	response to forskolin
0.41	GO:0043949	regulation of cAMP-mediated signaling
0.40	GO:1901655	cellular response to ketone

0.79	GO:0031683	G-protein beta/gamma-subunit complex binding
0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.63	GO:0004871	signal transducer activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0031821	G-protein coupled serotonin receptor binding
0.42	GO:0032794	GTPase activating protein binding
0.38	GO:0019904	protein domain specific binding

0.47	GO:0030496	midbody
0.46	GO:0005813	centrosome
0.45	GO:1905360	GTPase complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0005730	nucleolus
0.41	GO:0099738	cell cortex region
0.41	GO:0098797	plasma membrane protein complex
0.40	GO:0000139	Golgi membrane
0.40	GO:0042588	zymogen granule
0.40	GO:0005789	endoplasmic reticulum membrane

sp|P08909|5HT2C_RAT
5-hydroxytryptamine receptor 2C
Search

HTR2C

0.97	5-hydroxytryptamine (Serotonin) receptor 2C long isoform

0.82	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.81	GO:0007631	feeding behavior
0.78	GO:0007626	locomotory behavior
0.65	GO:0043397	regulation of corticotropin-releasing hormone secretion
0.64	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.62	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.62	GO:0001662	behavioral fear response
0.61	GO:0032098	regulation of appetite
0.61	GO:0051209	release of sequestered calcium ion into cytosol
0.61	GO:0031644	regulation of neurological system process

0.82	GO:0099589	serotonin receptor activity
0.79	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.78	GO:0008227	G-protein coupled amine receptor activity
0.66	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
0.63	GO:0051378	serotonin binding
0.34	GO:0005515	protein binding

0.64	GO:0005887	integral component of plasma membrane
0.38	GO:0009897	external side of plasma membrane
0.33	GO:0005622	intracellular

sp|P08911|ACM5_RAT
Muscarinic acetylcholine receptor M5
Search

CHRM5

0.81	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.84	GO:0022600	digestive system process
0.70	GO:0046717	acid secretion
0.65	GO:0032941	secretion by tissue
0.64	GO:0015872	dopamine transport
0.64	GO:0007589	body fluid secretion
0.61	GO:0019226	transmission of nerve impulse
0.58	GO:0045987	positive regulation of smooth muscle contraction
0.54	GO:0007271	synaptic transmission, cholinergic
0.53	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.43	GO:0042166	acetylcholine binding
0.37	GO:0004435	phosphatidylinositol phospholipase C activity
0.36	GO:0016934	extracellularly glycine-gated chloride channel activity
0.34	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.41	GO:0016323	basolateral plasma membrane
0.39	GO:0043679	axon terminus
0.39	GO:0032279	asymmetric synapse
0.38	GO:0030425	dendrite

0.37	EC:3.1.4.11	GO:0004435
0.37	KEGG:R03435	GO:0004435

sp|P08921|CD2_RAT
T-cell surface antigen CD2
Search

CD2

0.92	T-lymphocyte surface CD2 antigen

0.78	GO:1902715	positive regulation of interferon-gamma secretion
0.77	GO:2000484	positive regulation of interleukin-8 secretion
0.76	GO:0034113	heterotypic cell-cell adhesion
0.74	GO:0032760	positive regulation of tumor necrosis factor production
0.44	GO:0042110	T cell activation
0.42	GO:0030887	positive regulation of myeloid dendritic cell activation
0.40	GO:0001766	membrane raft polarization
0.39	GO:0030101	natural killer cell activation
0.39	GO:0045580	regulation of T cell differentiation
0.39	GO:0050900	leukocyte migration

0.63	GO:0005102	receptor binding
0.54	GO:0042803	protein homodimerization activity
0.42	GO:0003823	antigen binding
0.42	GO:0043621	protein self-association
0.42	GO:1990782	protein tyrosine kinase binding
0.36	GO:0004872	receptor activity

0.71	GO:0009897	external side of plasma membrane
0.58	GO:0046658	anchored component of plasma membrane
0.55	GO:0005911	cell-cell junction
0.55	GO:0009898	cytoplasmic side of plasma membrane
0.50	GO:0005576	extracellular region
0.41	GO:0045121	membrane raft
0.37	GO:0043234	protein complex
0.36	GO:0005887	integral component of plasma membrane

sp|P08932|KNT2_RAT
T-kininogen 2
Search

KNG1

0.95	High molecular weight kininogen II

0.76	GO:0010951	negative regulation of endopeptidase activity
0.62	GO:0030195	negative regulation of blood coagulation
0.59	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0007162	negative regulation of cell adhesion
0.48	GO:0042311	vasodilation
0.46	GO:0006954	inflammatory response
0.43	GO:0007596	blood coagulation
0.39	GO:0072376	protein activation cascade
0.37	GO:0002675	positive regulation of acute inflammatory response
0.37	GO:0010954	positive regulation of protein processing

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.52	GO:0005102	receptor binding
0.37	GO:0002020	protease binding
0.36	GO:0008201	heparin binding
0.34	GO:0008270	zinc ion binding

0.56	GO:0005615	extracellular space
0.53	GO:0031012	extracellular matrix
0.38	GO:1903561	extracellular vesicle
0.37	GO:0043204	perikaryon
0.37	GO:0031093	platelet alpha granule lumen
0.36	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005886	plasma membrane

sp|P08934|KNG1_RAT
Kininogen-1
Search

KNG1

0.94	High molecular weight kininogen II

0.76	GO:0010951	negative regulation of endopeptidase activity
0.63	GO:0030195	negative regulation of blood coagulation
0.60	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.56	GO:0007162	negative regulation of cell adhesion
0.48	GO:0042311	vasodilation
0.45	GO:0006954	inflammatory response
0.44	GO:0007596	blood coagulation
0.40	GO:0072376	protein activation cascade
0.39	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0010954	positive regulation of protein processing

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.53	GO:0005102	receptor binding
0.38	GO:0002020	protease binding
0.36	GO:0008201	heparin binding
0.34	GO:0008270	zinc ion binding

0.56	GO:0005615	extracellular space
0.54	GO:0031012	extracellular matrix
0.40	GO:1903561	extracellular vesicle
0.39	GO:0043204	perikaryon
0.37	GO:0031093	platelet alpha granule lumen
0.36	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005886	plasma membrane

sp|P08937|OBP_RAT
Odorant-binding protein
Search

0.48	Odorant binding protein 1

0.51

GO:0036094

small molecule binding

sp|P09005|SPI21_RAT
Serine protease inhibitor 2.1 (Fragment)
Search

0.73	Alpha-1-antichymotrypsin

0.54	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0043434	response to peptide hormone
0.40	GO:0034097	response to cytokine
0.38	GO:0006953	acute-phase response
0.38	GO:0006508	proteolysis
0.37	GO:1901342	regulation of vasculature development
0.36	GO:0090362	positive regulation of platelet-derived growth factor production
0.36	GO:0048522	positive regulation of cellular process
0.36	GO:0042127	regulation of cell proliferation
0.36	GO:0032914	positive regulation of transforming growth factor beta1 production

0.56	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0008233	peptidase activity
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.35	GO:0002020	protease binding
0.34	GO:0042802	identical protein binding
0.33	GO:0005496	steroid binding
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.42	GO:0042583	chromaffin granule
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031093	platelet alpha granule lumen
0.35	GO:0035578	azurophil granule lumen
0.34	GO:0005634	nucleus
0.34	GO:0005794	Golgi apparatus
0.34	GO:0005783	endoplasmic reticulum
0.32	GO:0005886	plasma membrane
0.32	GO:0031012	extracellular matrix

0.38

GO:0008233

sp|P09006|SPA3N_RAT
Serine protease inhibitor A3N
Search

0.74	Serine protease inhibitor

0.55	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0043434	response to peptide hormone
0.42	GO:0034097	response to cytokine
0.39	GO:0006954	inflammatory response
0.38	GO:0006508	proteolysis
0.37	GO:0034516	response to vitamin B6
0.37	GO:0006955	immune response
0.37	GO:0002576	platelet degranulation
0.36	GO:0071320	cellular response to cAMP
0.36	GO:0071385	cellular response to glucocorticoid stimulus

0.56	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0008233	peptidase activity
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.34	GO:0005515	protein binding
0.34	GO:0005496	steroid binding
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.43	GO:0042583	chromaffin granule
0.37	GO:1903561	extracellular vesicle
0.36	GO:0034774	secretory granule lumen
0.35	GO:0005766	primary lysosome
0.35	GO:0031091	platelet alpha granule
0.35	GO:0005775	vacuolar lumen
0.34	GO:0042827	platelet dense granule
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0008233

sp|P09011|MIP_RAT
Lens fiber major intrinsic protein (Fragment)
Search

MIP

0.94	Major intrinsic protein of eye lens fiber

0.65	GO:0006833	water transport
0.64	GO:1990349	gap junction-mediated intercellular transport
0.63	GO:0002088	lens development in camera-type eye
0.58	GO:0051289	protein homotetramerization
0.55	GO:0055085	transmembrane transport
0.54	GO:0045785	positive regulation of cell adhesion
0.53	GO:0007601	visual perception
0.41	GO:0006811	ion transport
0.40	GO:0071288	cellular response to mercury ion
0.39	GO:0071280	cellular response to copper ion

0.69	GO:0022803	passive transmembrane transporter activity
0.65	GO:0005372	water transmembrane transporter activity
0.58	GO:0005212	structural constituent of eye lens
0.42	GO:0005516	calmodulin binding
0.40	GO:0015168	glycerol transmembrane transporter activity
0.34	GO:0046983	protein dimerization activity

0.51	GO:0016324	apical plasma membrane
0.51	GO:0005783	endoplasmic reticulum
0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0005921	gap junction
0.38	GO:0009925	basal plasma membrane
0.38	GO:0070062	extracellular exosome
0.38	GO:0016328	lateral plasma membrane
0.37	GO:0055037	recycling endosome
0.35	GO:0009897	external side of plasma membrane
0.34	GO:0046930	pore complex

sp|P09034|ASSY_RAT
Argininosuccinate synthase
Search

ASS1

0.45	Argininosuccinate synthetase

0.72	GO:0006526	arginine biosynthetic process
0.62	GO:0000053	argininosuccinate metabolic process
0.59	GO:0000050	urea cycle
0.56	GO:0071499	cellular response to laminar fluid shear stress
0.55	GO:0000052	citrulline metabolic process
0.54	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.53	GO:1903038	negative regulation of leukocyte cell-cell adhesion
0.53	GO:0007623	circadian rhythm
0.52	GO:0006531	aspartate metabolic process
0.36	GO:0071418	cellular response to amine stimulus

0.80	GO:0004055	argininosuccinate synthase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0016597	amino acid binding
0.48	GO:0042802	identical protein binding
0.35	GO:0015643	toxic substance binding
0.34	GO:0003723	RNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.52	GO:0043209	myelin sheath
0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.36	GO:0070852	cell body fiber
0.35	GO:0043204	perikaryon
0.35	GO:0005764	lysosome
0.35	GO:0031968	organelle outer membrane
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus

0.80

EC:6.3.4.5

GO:0004055

sp|P09057|DCOR_RAT
Ornithine decarboxylase
Search

ODC1

0.48	Ornithine decarboxylase

0.74	GO:0006596	polyamine biosynthetic process
0.57	GO:0009445	putrescine metabolic process
0.55	GO:0001822	kidney development
0.54	GO:0006591	ornithine metabolic process
0.54	GO:0042176	regulation of protein catabolic process
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0009615	response to virus
0.44	GO:0042462	eye photoreceptor cell development
0.35	GO:0006521	regulation of cellular amino acid metabolic process

0.60	GO:0004586	ornithine decarboxylase activity
0.53	GO:0042803	protein homodimerization activity

0.49	GO:0005829	cytosol
0.39	GO:0048471	perinuclear region of cytoplasm

0.60	EC:4.1.1.17	GO:0004586
0.60	KEGG:R00670	GO:0004586

sp|P09117|ALDOC_RAT
Fructose-bisphosphate aldolase C
Search

ALDOC

0.55	Fructose-bisphosphate aldolase C

0.70	GO:0006096	glycolytic process
0.58	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.52	GO:0030855	epithelial cell differentiation
0.44	GO:0006000	fructose metabolic process
0.44	GO:0046716	muscle cell cellular homeostasis
0.44	GO:0007339	binding of sperm to zona pellucida
0.44	GO:0006941	striated muscle contraction
0.41	GO:0051289	protein homotetramerization
0.40	GO:0006754	ATP biosynthetic process
0.40	GO:0008360	regulation of cell shape

0.78	GO:0004332	fructose-bisphosphate aldolase activity
0.51	GO:0008092	cytoskeletal protein binding
0.46	GO:0070061	fructose binding
0.43	GO:0045296	cadherin binding
0.37	GO:0042802	identical protein binding
0.36	GO:0002020	protease binding
0.35	GO:0061609	fructose-1-phosphate aldolase activity
0.34	GO:0051117	ATPase binding
0.33	GO:0003723	RNA binding
0.33	GO:0004672	protein kinase activity

0.45	GO:0061827	sperm head
0.44	GO:0005739	mitochondrion
0.44	GO:0070062	extracellular exosome
0.41	GO:0015629	actin cytoskeleton
0.40	GO:0005829	cytosol
0.40	GO:0031430	M band
0.40	GO:0031674	I band
0.37	GO:1904724	tertiary granule lumen
0.37	GO:1904813	ficolin-1-rich granule lumen
0.37	GO:0035686	sperm fibrous sheath

0.78

EC:4.1.2.13

GO:0004332

sp|P09118|URIC_RAT
Uricase
Search

0.66

Uricase

0.77	GO:0019628	urate catabolic process
0.73	GO:0006144	purine nucleobase metabolic process
0.52	GO:0055114	oxidation-reduction process
0.43	GO:0007031	peroxisome organization
0.35	GO:0046113	nucleobase catabolic process
0.33	GO:0009877	nodulation

0.84	GO:0004846	urate oxidase activity
0.33	GO:0008270	zinc ion binding

0.69	GO:0005777	peroxisome
0.43	GO:0005739	mitochondrion
0.36	GO:0031907	microbody lumen
0.33	GO:0045335	phagocytic vesicle
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:1.7.3.3

GO:0004846

sp|P09139|SPYA_RAT
Serine--pyruvate aminotransferase, mitochondrial
Search

AGXT

0.84	Serine--pyruvate aminotransferase

0.61	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate
0.60	GO:0046724	oxalic acid secretion
0.60	GO:0019448	L-cysteine catabolic process
0.56	GO:0009436	glyoxylate catabolic process
0.54	GO:0007219	Notch signaling pathway
0.54	GO:0042853	L-alanine catabolic process
0.40	GO:0051591	response to cAMP
0.40	GO:0051384	response to glucocorticoid
0.39	GO:0071391	cellular response to estrogen stimulus
0.39	GO:0042866	pyruvate biosynthetic process

0.80	GO:0004760	serine-pyruvate transaminase activity
0.80	GO:0008453	alanine-glyoxylate transaminase activity
0.57	GO:0043621	protein self-association
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0016597	amino acid binding
0.50	GO:0005102	receptor binding
0.47	GO:0070279	vitamin B6 binding
0.44	GO:0050662	coenzyme binding
0.36	GO:0004038	allantoinase activity
0.36	GO:0050897	cobalt ion binding

0.56	GO:0031907	microbody lumen
0.54	GO:0005777	peroxisome
0.40	GO:0005759	mitochondrial matrix

0.80	EC:2.6.1.51	GO:0004760
0.80	KEGG:R00585	GO:0004760

sp|P09215|KPCD_RAT
Protein kinase C delta type
Search

PRKCD

0.97	Protein kinase C delta type

0.68	GO:0006915	apoptotic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.60	GO:2000753	positive regulation of glucosylceramide catabolic process
0.60	GO:2000755	positive regulation of sphingomyelin catabolic process
0.59	GO:1900163	positive regulation of phospholipid scramblase activity
0.59	GO:0023021	termination of signal transduction
0.58	GO:2000304	positive regulation of ceramide biosynthetic process
0.58	GO:0051490	negative regulation of filopodium assembly
0.58	GO:0032613	interleukin-10 production

0.82	GO:0004697	protein kinase C activity
0.56	GO:0043560	insulin receptor substrate binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0046872	metal ion binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0008047	enzyme activator activity
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.67	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0005634	nucleus
0.51	GO:0005911	cell-cell junction
0.48	GO:0005783	endoplasmic reticulum
0.48	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0042582	azurophil granule

0.82

GO:0004697

sp|P09216|KPCE_RAT
Protein kinase C epsilon type
Search

PRKCE

0.97	Protein kinase C epsilon type

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0035669	TRAM-dependent toll-like receptor 4 signaling pathway
0.61	GO:2001031	positive regulation of cellular glucuronidation
0.59	GO:0010763	positive regulation of fibroblast migration
0.59	GO:0002281	macrophage activation involved in immune response
0.59	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.59	GO:0070257	positive regulation of mucus secretion
0.58	GO:0043278	response to morphine
0.58	GO:0071380	cellular response to prostaglandin E stimulus

0.80	GO:0004697	protein kinase C activity
0.60	GO:0035276	ethanol binding
0.59	GO:0030546	receptor activator activity
0.58	GO:0071889	14-3-3 protein binding
0.57	GO:0003785	actin monomer binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.51	GO:0008047	enzyme activator activity

0.57	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005856	cytoskeleton
0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.45	GO:0005739	mitochondrion
0.44	GO:0005886	plasma membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment

0.80

GO:0004697

sp|P09217|KPCZ_RAT
Protein kinase C zeta type
Search

PRKCZ

0.84	Protein kinase C zeta type

0.62	GO:0006468	protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.56	GO:2001181	positive regulation of interleukin-10 secretion
0.56	GO:2000667	positive regulation of interleukin-13 secretion
0.56	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.56	GO:2000664	positive regulation of interleukin-5 secretion
0.56	GO:2000553	positive regulation of T-helper 2 cell cytokine production
0.54	GO:0032753	positive regulation of interleukin-4 production
0.53	GO:0046627	negative regulation of insulin receptor signaling pathway
0.53	GO:0018209	peptidyl-serine modification

0.79	GO:0004697	protein kinase C activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.52	GO:0046872	metal ion binding
0.39	GO:0043274	phospholipase binding
0.39	GO:0071889	14-3-3 protein binding
0.39	GO:0015459	potassium channel regulator activity
0.37	GO:0019901	protein kinase binding

0.55	GO:0035748	myelin sheath abaxonal region
0.55	GO:0043203	axon hillock
0.54	GO:0045179	apical cortex
0.52	GO:0016363	nuclear matrix
0.51	GO:0016324	apical plasma membrane
0.51	GO:0005923	bicellular tight junction
0.49	GO:0005635	nuclear envelope
0.48	GO:0005815	microtubule organizing center
0.47	GO:0031982	vesicle
0.46	GO:0005829	cytosol

0.79

GO:0004697

sp|P09320|PR4A1_RAT
Prolactin-4A1
Search

PRL

0.91

Prolactin

0.76	GO:0010469	regulation of receptor activity
0.53	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.52	GO:0001937	negative regulation of endothelial cell proliferation
0.52	GO:0046427	positive regulation of JAK-STAT cascade
0.51	GO:0040014	regulation of multicellular organism growth
0.46	GO:0007595	lactation
0.44	GO:0001666	response to hypoxia
0.37	GO:0010817	regulation of hormone levels
0.36	GO:0051602	response to electrical stimulus
0.36	GO:0009648	photoperiodism

0.79	GO:0005179	hormone activity
0.40	GO:0005148	prolactin receptor binding
0.35	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.35	GO:0031904	endosome lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P09321|PR3B1_RAT
Prolactin-3B1
Search

PRL

0.64	Chorionic somatomammotropin hormone 2

0.76	GO:0010469	regulation of receptor activity
0.41	GO:0050678	regulation of epithelial cell proliferation
0.40	GO:0008284	positive regulation of cell proliferation
0.40	GO:0048609	multicellular organismal reproductive process
0.39	GO:0007262	STAT protein import into nucleus
0.39	GO:0007567	parturition
0.39	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.39	GO:0007595	lactation
0.38	GO:0032355	response to estradiol
0.38	GO:0046427	positive regulation of JAK-STAT cascade

0.79	GO:0005179	hormone activity
0.40	GO:0005148	prolactin receptor binding

0.66	GO:0005576	extracellular region
0.40	GO:0030141	secretory granule
0.30	GO:0016020	membrane

sp|P09330|PRPS2_RAT
Ribose-phosphate pyrophosphokinase 2
Search

PRPS2

0.85	Phosphoribosyl pyrophosphate synthetase 2

0.66	GO:0009116	nucleoside metabolic process
0.64	GO:0009156	ribonucleoside monophosphate biosynthetic process
0.64	GO:0009165	nucleotide biosynthetic process
0.60	GO:0034418	urate biosynthetic process
0.54	GO:0046101	hypoxanthine biosynthetic process
0.50	GO:0007399	nervous system development
0.44	GO:0006163	purine nucleotide metabolic process
0.38	GO:0016310	phosphorylation

0.78	GO:0004749	ribose phosphate diphosphokinase activity
0.64	GO:0000287	magnesium ion binding
0.59	GO:0042802	identical protein binding
0.48	GO:0046983	protein dimerization activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016301	kinase activity

0.78	EC:2.7.6.1	GO:0004749
0.78	KEGG:R01049	GO:0004749

sp|P09367|SDHL_RAT
L-serine dehydratase/L-threonine deaminase
Search

SDS

0.55	L-serine dehydratase/L-threonine deaminase

0.64	GO:0006565	L-serine catabolic process
0.59	GO:0042866	pyruvate biosynthetic process
0.39	GO:0019319	hexose biosynthetic process
0.39	GO:0006006	glucose metabolic process
0.39	GO:0033590	response to cobalamin
0.37	GO:0043200	response to amino acid
0.33	GO:0006567	threonine catabolic process
0.33	GO:0006468	protein phosphorylation

0.64	GO:0030170	pyridoxal phosphate binding
0.58	GO:0003941	L-serine ammonia-lyase activity
0.56	GO:0042802	identical protein binding
0.51	GO:0046983	protein dimerization activity
0.42	GO:0004794	L-threonine ammonia-lyase activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005829	cytosol
0.47	GO:0005739	mitochondrion
0.35	GO:0070062	extracellular exosome
0.33	GO:0009295	nucleoid
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.58

EC:4.3.1.17

GO:0003941

sp|P09414|NFIA_RAT
Nuclear factor 1 A-type
Search

NFIA

0.77	Nuclear factor 1 A-type

0.66	GO:0006260	DNA replication
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0060074	synapse maturation
0.54	GO:0072189	ureter development
0.49	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.49	GO:0003682	chromatin binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.48	GO:0030054	cell junction
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P09416|MYC_RAT
Myc proto-oncogene protein
Search

MYC

0.93	MYC proto-oncogene, bHLH transcription factor

0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0045656	negative regulation of monocyte differentiation
0.55	GO:0048146	positive regulation of fibroblast proliferation
0.54	GO:0010332	response to gamma radiation
0.54	GO:2000573	positive regulation of DNA biosynthetic process
0.53	GO:0060070	canonical Wnt signaling pathway
0.53	GO:2001022	positive regulation of response to DNA damage stimulus
0.53	GO:0032204	regulation of telomere maintenance
0.53	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.53	GO:0050679	positive regulation of epithelial cell proliferation

0.62	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0070888	E-box binding
0.49	GO:0032403	protein complex binding
0.39	GO:0070491	repressing transcription factor binding
0.39	GO:0033613	activating transcription factor binding
0.39	GO:0071074	eukaryotic initiation factor eIF2 binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0003729	mRNA binding

0.61	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005791	rough endoplasmic reticulum
0.37	GO:0030424	axon
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0042025	host cell nucleus
0.35	GO:0005739	mitochondrion
0.35	GO:0043234	protein complex

sp|P09456|KAP0_RAT
cAMP-dependent protein kinase type I-alpha regulatory subunit
Search

PRKAR1A

0.97	cAMP-dependent protein kinase type I-alpha regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.57	GO:0046007	negative regulation of activated T cell proliferation
0.56	GO:0060038	cardiac muscle cell proliferation
0.56	GO:0033673	negative regulation of kinase activity
0.54	GO:0045214	sarcomere organization
0.54	GO:0001707	mesoderm formation
0.53	GO:0001933	negative regulation of protein phosphorylation
0.50	GO:0016310	phosphorylation
0.42	GO:0007611	learning or memory
0.40	GO:0051445	regulation of meiotic cell cycle

0.84	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.60	GO:0034236	protein kinase A catalytic subunit binding
0.59	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.52	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0016301	kinase activity
0.51	GO:0019904	protein domain specific binding
0.34	GO:0042802	identical protein binding
0.33	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.56	GO:0001772	immunological synapse
0.55	GO:0031588	nucleotide-activated protein kinase complex
0.54	GO:0044853	plasma membrane raft
0.54	GO:0031594	neuromuscular junction
0.53	GO:0005930	axoneme
0.35	GO:0097546	ciliary base
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.32

GO:0016773

sp|P09483|ACHA4_RAT
Neuronal acetylcholine receptor subunit alpha-4
Search

CHRNA4

0.94	Cholinergic receptor nicotinic alpha 4 subunit

0.78	GO:0060079	excitatory postsynaptic potential
0.74	GO:0035094	response to nicotine
0.70	GO:0007271	synaptic transmission, cholinergic
0.70	GO:0060080	inhibitory postsynaptic potential
0.68	GO:0014059	regulation of dopamine secretion
0.68	GO:0035640	exploration behavior
0.68	GO:0007585	respiratory gaseous exchange
0.67	GO:0051899	membrane depolarization
0.67	GO:0019233	sensory perception of pain
0.66	GO:0001508	action potential

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.71	GO:0015464	acetylcholine receptor activity
0.56	GO:0042166	acetylcholine binding

0.77	GO:0045211	postsynaptic membrane
0.73	GO:0005892	acetylcholine-gated channel complex
0.72	GO:0030054	cell junction
0.64	GO:0009897	external side of plasma membrane

sp|P09495|TPM4_RAT
Tropomyosin alpha-4 chain
Search

TPM4

0.84	Cytoskeletal tropomyosin

0.70	GO:0006936	muscle contraction
0.63	GO:0097435	supramolecular fiber organization
0.63	GO:0030036	actin cytoskeleton organization
0.56	GO:0055013	cardiac muscle cell development
0.55	GO:0060047	heart contraction
0.54	GO:0010927	cellular component assembly involved in morphogenesis
0.49	GO:0070925	organelle assembly
0.44	GO:0001649	osteoblast differentiation
0.41	GO:0033275	actin-myosin filament sliding

0.68	GO:0008307	structural constituent of muscle
0.61	GO:0051015	actin filament binding
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0046982	protein heterodimerization activity
0.39	GO:0046872	metal ion binding
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0005884	actin filament
0.71	GO:0097517	contractile actin filament bundle
0.71	GO:0042641	actomyosin
0.70	GO:0005862	muscle thin filament tropomyosin
0.66	GO:0002102	podosome
0.62	GO:0030863	cortical cytoskeleton
0.43	GO:0005925	focal adhesion
0.43	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P09527|RAB7A_RAT
Ras-related protein Rab-7a
Search

RAB7A

0.94	RAB7A, member RAS oncogene family

0.58	GO:0061724	lipophagy
0.57	GO:0007174	epidermal growth factor catabolic process
0.56	GO:0090383	phagosome acidification
0.56	GO:0090385	phagosome-lysosome fusion
0.56	GO:1903542	negative regulation of exosomal secretion
0.55	GO:0022615	protein to membrane docking
0.55	GO:0045022	early endosome to late endosome transport
0.54	GO:1903543	positive regulation of exosomal secretion
0.54	GO:0006622	protein targeting to lysosome
0.53	GO:0008333	endosome to lysosome transport

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.56	GO:1905394	retromer complex binding
0.53	GO:0019003	GDP binding
0.40	GO:0048365	Rac GTPase binding

0.57	GO:0032419	extrinsic component of lysosome membrane
0.55	GO:0005770	late endosome
0.53	GO:0045335	phagocytic vesicle
0.52	GO:0005811	lipid droplet
0.52	GO:0034045	phagophore assembly site membrane
0.52	GO:0010008	endosome membrane
0.51	GO:0030904	retromer complex
0.47	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.42	GO:0033162	melanosome membrane

sp|P09605|KCRS_RAT
Creatine kinase S-type, mitochondrial
Search

CKMT2

0.97	Mitochondrial creatine kinase

0.56	GO:0016310	phosphorylation
0.38	GO:0006600	creatine metabolic process
0.37	GO:0032091	negative regulation of protein binding
0.37	GO:0006599	phosphagen metabolic process
0.36	GO:0043066	negative regulation of apoptotic process
0.35	GO:0007519	skeletal muscle tissue development
0.35	GO:0006936	muscle contraction
0.35	GO:0007507	heart development

0.59	GO:0016301	kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.36	GO:1901612	cardiolipin binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005739	mitochondrion
0.39	GO:0019866	organelle inner membrane
0.37	GO:0043209	myelin sheath
0.35	GO:0070062	extracellular exosome

0.41

GO:0016775

sp|P09606|GLNA_RAT
Glutamine synthetase
Search

GLUL

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.49	GO:0008283	cell proliferation
0.49	GO:0009749	response to glucose
0.46	GO:0009267	cellular response to starvation
0.39	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.39	GO:0019676	ammonia assimilation cycle
0.39	GO:0032024	positive regulation of insulin secretion
0.38	GO:0050679	positive regulation of epithelial cell proliferation
0.38	GO:0051260	protein homooligomerization
0.35	GO:0001505	regulation of neurotransmitter levels

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042802	identical protein binding
0.43	GO:0004351	glutamate decarboxylase activity
0.40	GO:0016595	glutamate binding
0.39	GO:0045503	dynein light chain binding
0.37	GO:0030145	manganese ion binding
0.36	GO:0000287	magnesium ion binding

0.51	GO:0097386	glial cell projection
0.48	GO:0043209	myelin sheath
0.47	GO:0044297	cell body
0.45	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0036477	somatodendritic compartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|P09626|ATP4A_RAT
Potassium-transporting ATPase alpha chain 1
Search

ATP4A

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.83	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.74	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.71	GO:0006814	sodium ion transport
0.70	GO:0006813	potassium ion transport
0.62	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.57	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient
0.40	GO:0006885	regulation of pH
0.39	GO:0055075	potassium ion homeostasis
0.38	GO:0010155	regulation of proton transport
0.36	GO:0001696	gastric acid secretion

0.83	GO:0005391	sodium:potassium-exchanging ATPase activity
0.69	GO:0008900	potassium:proton exchanging ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.36	GO:0046982	protein heterodimerization activity

0.39	GO:0098590	plasma membrane region
0.36	GO:0045177	apical part of cell
0.36	GO:0005615	extracellular space
0.34	GO:0005887	integral component of plasma membrane

0.83

GO:0005391

sp|P09634|HXA7_RAT
Homeobox protein Hox-A7 (Fragment)
Search

HOXA7

0.73	Homeobox protein Hox-A7

0.64	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0045617	negative regulation of keratinocyte differentiation
0.57	GO:0045656	negative regulation of monocyte differentiation
0.56	GO:0010468	regulation of gene expression
0.55	GO:0002686	negative regulation of leukocyte migration
0.55	GO:0001953	negative regulation of cell-matrix adhesion
0.52	GO:0048863	stem cell differentiation
0.50	GO:0006366	transcription by RNA polymerase II

0.65	GO:0043565	sequence-specific DNA binding
0.57	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.49	GO:0008134	transcription factor binding
0.35	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.46	GO:0012505	endomembrane system
0.46	GO:0043233	organelle lumen
0.43	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane

sp|P09635|HXA4_RAT
Homeobox protein Hox-A4 (Fragment)
Search

0.83	Homeobox protein Hox-A4 (Fragment)

0.64	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0009653	anatomical structure morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part

sp|P09650|MCPT1_RAT
Mast cell protease 1
Search

0.94	Skeletal muscle neutral protease mekratin

0.61	GO:0006508	proteolysis
0.52	GO:0042222	interleukin-1 biosynthetic process
0.50	GO:0034769	basement membrane disassembly
0.50	GO:0032611	interleukin-1 beta production
0.45	GO:0001909	leukocyte mediated cytotoxicity
0.45	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.44	GO:0002443	leukocyte mediated immunity
0.43	GO:0051873	killing by host of symbiont cells
0.42	GO:0050830	defense response to Gram-positive bacterium
0.42	GO:0019731	antibacterial humoral response

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0008201	heparin binding
0.38	GO:0042277	peptide binding
0.33	GO:0005515	protein binding

0.58	GO:0030141	secretory granule
0.47	GO:0031012	extracellular matrix
0.41	GO:0010494	cytoplasmic stress granule
0.41	GO:0005615	extracellular space
0.39	GO:0042629	mast cell granule
0.35	GO:0005886	plasma membrane
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen
0.34	GO:1903561	extracellular vesicle

0.69

GO:0004252

sp|P09655|ISK1_RAT
Serine protease inhibitor Kazal-type 1
Search

SPINK1

0.60	pancreatic secretory trypsin inhibitor

0.64	GO:0010951	negative regulation of endopeptidase activity
0.63	GO:1902572	negative regulation of serine-type peptidase activity
0.63	GO:1900003	regulation of serine-type endopeptidase activity
0.62	GO:0060046	regulation of acrosome reaction
0.61	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.59	GO:0090281	negative regulation of calcium ion import
0.59	GO:0048240	sperm capacitation
0.58	GO:2001256	regulation of store-operated calcium entry
0.58	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.48	GO:1901699	cellular response to nitrogen compound

0.66	GO:0004867	serine-type endopeptidase inhibitor activity
0.48	GO:0043236	laminin binding
0.47	GO:0008233	peptidase activity
0.45	GO:0005509	calcium ion binding
0.36	GO:0008061	chitin binding
0.36	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.34	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0016788	hydrolase activity, acting on ester bonds

0.53	GO:0005615	extracellular space
0.52	GO:0001669	acrosomal vesicle
0.42	GO:1903561	extracellular vesicle
0.38	GO:0005886	plasma membrane
0.36	GO:0005605	basal lamina
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.47

GO:0008233

sp|P09656|ISK1L_RAT
Serine protease inhibitor Kazal-type 1-like
Search

SPINK1

0.95	pancreatic secretory trypsin inhibitor

0.73	GO:1900004	negative regulation of serine-type endopeptidase activity
0.67	GO:0060046	regulation of acrosome reaction
0.64	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.62	GO:0090281	negative regulation of calcium ion import
0.62	GO:0048240	sperm capacitation
0.61	GO:2001256	regulation of store-operated calcium entry
0.61	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.50	GO:0002787	negative regulation of antibacterial peptide production
0.46	GO:0009913	epidermal cell differentiation
0.44	GO:0030155	regulation of cell adhesion

0.73	GO:0004867	serine-type endopeptidase inhibitor activity
0.44	GO:0008233	peptidase activity
0.39	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding

0.58	GO:0030141	secretory granule
0.57	GO:0005615	extracellular space
0.54	GO:0097223	sperm part
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005938	cell cortex
0.43	GO:0005789	endoplasmic reticulum membrane
0.43	GO:1903561	extracellular vesicle
0.42	GO:0005829	cytosol
0.38	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0008233

sp|P09660|ACHE_RAT
Acetylcholine receptor subunit epsilon
Search

CHRNE

0.91	Nicotinic acetylcholine receptor subunit epsilon

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.54	GO:0007271	synaptic transmission, cholinergic
0.53	GO:0035094	response to nicotine
0.52	GO:0007274	neuromuscular synaptic transmission
0.43	GO:0006936	muscle contraction
0.41	GO:0050881	musculoskeletal movement
0.41	GO:0006812	cation transport

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.54	GO:0042166	acetylcholine binding
0.35	GO:0005515	protein binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.53	GO:0005892	acetylcholine-gated channel complex

sp|P09739|TNNT3_RAT
Troponin T, fast skeletal muscle
Search

TNNT3

0.94	Troponin T fast skeletal muscle type

0.84	GO:0006942	regulation of striated muscle contraction
0.52	GO:0003009	skeletal muscle contraction
0.48	GO:0043462	regulation of ATPase activity
0.35	GO:0030049	muscle filament sliding
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.54	GO:0030899	calcium-dependent ATPase activity
0.54	GO:0030172	troponin C binding
0.54	GO:0031013	troponin I binding
0.51	GO:0048306	calcium-dependent protein binding
0.51	GO:0005523	tropomyosin binding
0.47	GO:0003779	actin binding
0.35	GO:0031014	troponin T binding
0.34	GO:0003735	structural constituent of ribosome

0.82	GO:0005861	troponin complex
0.33	GO:0005840	ribosome
0.33	GO:0005829	cytosol

sp|P09759|EPHB1_RAT
Ephrin type-B receptor 1
Search

EPHB1

0.96	EPH receptor B1

0.83	GO:0048013	ephrin receptor signaling pathway
0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.74	GO:0014719	skeletal muscle satellite cell activation
0.73	GO:1902723	negative regulation of skeletal muscle satellite cell proliferation
0.73	GO:0021631	optic nerve morphogenesis
0.72	GO:1902725	negative regulation of satellite cell differentiation
0.72	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.71	GO:0060997	dendritic spine morphogenesis
0.70	GO:0021952	central nervous system projection neuron axonogenesis
0.70	GO:0031290	retinal ganglion cell axon guidance

0.84	GO:0005003	ephrin receptor activity
0.73	GO:0008046	axon guidance receptor activity
0.61	GO:0032403	protein complex binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0032433	filopodium tip
0.66	GO:0005887	integral component of plasma membrane
0.66	GO:0031901	early endosome membrane
0.65	GO:0045121	membrane raft
0.65	GO:0030424	axon
0.56	GO:0005783	endoplasmic reticulum
0.55	GO:0005829	cytosol

sp|P09760|FER_RAT
Tyrosine-protein kinase Fer
Search

FER

0.61	Tyrosine-protein kinase

0.81	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.80	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.77	GO:0030335	positive regulation of cell migration
0.76	GO:0008283	cell proliferation
0.73	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0031532	actin cytoskeleton reorganization
0.61	GO:0050904	diapedesis
0.60	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase
0.60	GO:0036005	response to macrophage colony-stimulating factor
0.60	GO:0033006	regulation of mast cell activation involved in immune response

0.83	GO:0005154	epidermal growth factor receptor binding
0.77	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.57	GO:0008157	protein phosphatase 1 binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008289	lipid binding

0.63	GO:0005856	cytoskeleton
0.56	GO:0030027	lamellipodium
0.55	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.52	GO:0000790	nuclear chromatin
0.52	GO:0030054	cell junction
0.49	GO:0005829	cytosol

0.77

EC:2.7.10.2

GO:0004715

sp|P09810|TPH1_RAT
Tryptophan 5-hydroxylase 1
Search

TPH1

0.94	Tryptophan hydroxylase

0.85	GO:0042427	serotonin biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.55	GO:0046849	bone remodeling
0.55	GO:0045600	positive regulation of fat cell differentiation
0.54	GO:0061377	mammary gland lobule development
0.52	GO:0055114	oxidation-reduction process
0.41	GO:0035902	response to immobilization stress
0.40	GO:0007623	circadian rhythm
0.40	GO:0030279	negative regulation of ossification
0.36	GO:0006586	indolalkylamine metabolic process

0.85	GO:0004510	tryptophan 5-monooxygenase activity
0.62	GO:0005506	iron ion binding

0.42	GO:0043005	neuron projection
0.38	GO:0005737	cytoplasm

0.85

EC:1.14.16.4

GO:0004510

sp|P09811|PYGL_RAT
Glycogen phosphorylase, liver form
Search

PYGL

0.50	Alpha-1,4 glucan phosphorylase

0.60	GO:0005975	carbohydrate metabolic process
0.53	GO:0070266	necroptotic process
0.52	GO:0006112	energy reserve metabolic process
0.50	GO:0042593	glucose homeostasis
0.43	GO:0009057	macromolecule catabolic process
0.41	GO:0044248	cellular catabolic process
0.39	GO:0044260	cellular macromolecule metabolic process

0.80	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.80	GO:0102499	SHG alpha-glucan phosphorylase activity
0.79	GO:0008184	glycogen phosphorylase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.55	GO:0002060	purine nucleobase binding
0.53	GO:0032052	bile acid binding
0.49	GO:0016208	AMP binding
0.40	GO:0005524	ATP binding

0.37	GO:0045177	apical part of cell
0.37	GO:0048471	perinuclear region of cytoplasm

sp|P09812|PYGM_RAT
Glycogen phosphorylase, muscle form
Search

PYGM

0.71	Glycogen phosphorylase, muscle form

0.74	GO:0005977	glycogen metabolic process
0.68	GO:0009251	glucan catabolic process
0.68	GO:0044247	cellular polysaccharide catabolic process
0.46	GO:0051591	response to cAMP
0.46	GO:0043312	neutrophil degranulation
0.45	GO:0001666	response to hypoxia
0.45	GO:0006874	cellular calcium ion homeostasis

0.80	GO:0008184	glycogen phosphorylase activity
0.79	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.79	GO:0102499	SHG alpha-glucan phosphorylase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.48	GO:0005515	protein binding
0.46	GO:0030246	carbohydrate binding
0.46	GO:1901265	nucleoside phosphate binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0043169	cation binding

0.58	GO:0070062	extracellular exosome
0.50	GO:0030016	myofibril
0.49	GO:0030424	axon
0.47	GO:0035578	azurophil granule lumen
0.46	GO:0016529	sarcoplasmic reticulum
0.45	GO:0044449	contractile fiber part
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P09875|UD2B1_RAT
UDP-glucuronosyltransferase 2B1
Search

0.53	UDP-glucuronosyltransferase

0.51	GO:0052695	cellular glucuronidation
0.39	GO:0008202	steroid metabolic process
0.39	GO:0070980	biphenyl catabolic process
0.38	GO:0071394	cellular response to testosterone stimulus
0.37	GO:0071361	cellular response to ethanol
0.37	GO:0071378	cellular response to growth hormone stimulus
0.37	GO:0071385	cellular response to glucocorticoid stimulus
0.37	GO:0032496	response to lipopolysaccharide
0.37	GO:0034754	cellular hormone metabolic process
0.36	GO:0007608	sensory perception of smell

0.80	GO:0015020	glucuronosyltransferase activity
0.41	GO:0001972	retinoic acid binding

0.42	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.39	GO:0031090	organelle membrane
0.37	GO:0044444	cytoplasmic part
0.34	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0015020

sp|P09895|RL5_RAT
60S ribosomal protein L5
Search

RPL5

0.61	Ribosomal protein L5 (Predicted)

0.60	GO:0006518	peptide metabolic process
0.60	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0000027	ribosomal large subunit assembly
0.47	GO:2000435	negative regulation of protein neddylation
0.46	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.46	GO:1904667	negative regulation of ubiquitin protein ligase activity

0.79	GO:0008097	5S rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.47	GO:1990948	ubiquitin ligase inhibitor activity
0.44	GO:0003730	mRNA 3'-UTR binding
0.44	GO:0048027	mRNA 5'-UTR binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0017048	Rho GTPase binding
0.33	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein

0.61	GO:0005840	ribosome
0.45	GO:0005829	cytosol
0.44	GO:0005730	nucleolus
0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0005654	nucleoplasm
0.38	GO:0043234	protein complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.33

GO:0016773

sp|P09916|SLIB_RAT
Somatoliberin
Search

GHRH

0.88	somatoliberin precursor

0.76	GO:0010469	regulation of receptor activity
0.72	GO:0030252	growth hormone secretion
0.71	GO:0060124	positive regulation of growth hormone secretion
0.70	GO:0021984	adenohypophysis development
0.70	GO:0032094	response to food
0.68	GO:0040018	positive regulation of multicellular organism growth
0.66	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.63	GO:0008284	positive regulation of cell proliferation
0.56	GO:0030819	positive regulation of cAMP biosynthetic process
0.55	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep

0.79	GO:0005179	hormone activity
0.74	GO:0031770	growth hormone-releasing hormone receptor binding

0.67	GO:0043195	terminal bouton
0.66	GO:0005576	extracellular region
0.50	GO:0043204	perikaryon
0.40	GO:0005622	intracellular

sp|P09951|SYN1_RAT
Synapsin-1
Search

SYN1

0.90	Synapsin IIb

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0051649	establishment of localization in cell
0.55	GO:0097479	synaptic vesicle localization
0.38	GO:0099177	regulation of trans-synaptic signaling
0.37	GO:1902803	regulation of synaptic vesicle transport
0.37	GO:0098693	regulation of synaptic vesicle cycle
0.37	GO:0051588	regulation of neurotransmitter transport

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0019901	protein kinase binding
0.39	GO:0048306	calcium-dependent protein binding
0.39	GO:0003779	actin binding
0.35	GO:0046983	protein dimerization activity
0.33	GO:0005215	transporter activity
0.33	GO:0046872	metal ion binding

0.82	GO:0008021	synaptic vesicle
0.59	GO:0099501	exocytic vesicle membrane
0.57	GO:0014069	postsynaptic density
0.57	GO:0043209	myelin sheath
0.56	GO:0000795	synaptonemal complex
0.55	GO:0048786	presynaptic active zone
0.54	GO:0030424	axon
0.49	GO:0005856	cytoskeleton
0.41	GO:0031201	SNARE complex
0.40	GO:0030054	cell junction

sp|P0C089|PTPM1_RAT
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Search

PTPMT1

0.94	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.41	GO:0033566	gamma-tubulin complex localization
0.38	GO:0032049	cardiolipin biosynthetic process
0.36	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.36	GO:0016567	protein ubiquitination
0.36	GO:0046488	phosphatidylinositol metabolic process
0.34	GO:0006497	protein lipidation
0.33	GO:0009247	glycolipid biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
0.39	GO:0008962	phosphatidylglycerophosphatase activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0005515	protein binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.41	GO:0008274	gamma-tubulin ring complex
0.40	GO:0005739	mitochondrion
0.37	GO:0005680	anaphase-promoting complex
0.36	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.78	EC:3.1.3	GO:0008138
0.51	KEGG:R04404	GO:0004439

sp|P0C0A1|VPS25_RAT
Vacuolar protein-sorting-associated protein 25
Search

VPS25

0.91	WNK lysine deficient protein kinase 4

0.81	GO:0071985	multivesicular body sorting pathway
0.54	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.47	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.47	GO:0045324	late endosome to vacuole transport
0.47	GO:0072666	establishment of protein localization to vacuole
0.43	GO:0006886	intracellular protein transport
0.39	GO:0006468	protein phosphorylation
0.38	GO:0070294	renal sodium ion absorption
0.36	GO:0036258	multivesicular body assembly
0.35	GO:0006351	transcription, DNA-templated

0.53	GO:0047485	protein N-terminus binding
0.51	GO:0042803	protein homodimerization activity
0.40	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0005198	structural molecule activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding
0.35	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity
0.34	GO:0019869	chloride channel inhibitor activity

0.83	GO:0000814	ESCRT II complex
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.35	GO:0031515	tRNA (m1A) methyltransferase complex
0.34	GO:0005739	mitochondrion
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005923	bicellular tight junction

0.40

GO:0004674

sp|P0C0A2|VPS36_RAT
Vacuolar protein-sorting-associated protein 36
Search

VPS36

0.91	Vacuolar protein-sorting-associated protein 36

0.78	GO:0032509	endosome transport via multivesicular body sorting pathway
0.48	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.47	GO:0045324	late endosome to vacuole transport
0.47	GO:0072666	establishment of protein localization to vacuole
0.43	GO:0006886	intracellular protein transport
0.35	GO:0036258	multivesicular body assembly
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.79	GO:0032266	phosphatidylinositol-3-phosphate binding
0.77	GO:0043130	ubiquitin binding
0.55	GO:0008022	protein C-terminus binding
0.35	GO:0003730	mRNA 3'-UTR binding

0.79	GO:0000814	ESCRT II complex
0.56	GO:0031902	late endosome membrane
0.53	GO:0005764	lysosome
0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus

sp|P0C0A9|SVIP_RAT
Small VCP/p97-interacting protein
Search

SVIP

0.97	Small VCP interacting protein

0.87	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process
0.87	GO:1903061	positive regulation of protein lipidation
0.87	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.81	GO:0031333	negative regulation of protein complex assembly
0.80	GO:0010508	positive regulation of autophagy
0.62	GO:1904239	regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly
0.45	GO:0043312	neutrophil degranulation

0.85	GO:0051117	ATPase binding
0.85	GO:0043621	protein self-association

0.86	GO:0036513	Derlin-1 retrotranslocation complex
0.80	GO:0031225	anchored component of membrane
0.63	GO:0030868	smooth endoplasmic reticulum membrane
0.53	GO:0000139	Golgi membrane
0.49	GO:0070062	extracellular exosome
0.46	GO:0070821	tertiary granule membrane
0.43	GO:0005886	plasma membrane

sp|P0C0K5|HAVR2_RAT
Hepatitis A virus cellular receptor 2 homolog
Search

HAVCR2

0.97	Hepatitis A virus cellular receptor 2

0.68	GO:0071656	negative regulation of granulocyte colony-stimulating factor production
0.68	GO:0032712	negative regulation of interleukin-3 production
0.68	GO:0002519	natural killer cell tolerance induction
0.68	GO:2000521	negative regulation of immunological synapse formation
0.68	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.68	GO:2001189	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.67	GO:0002652	regulation of tolerance induction dependent upon immune response
0.66	GO:0002826	negative regulation of T-helper 1 type immune response
0.66	GO:0030886	negative regulation of myeloid dendritic cell activation
0.66	GO:0032687	negative regulation of interferon-alpha production

0.47	GO:0001104	RNA polymerase II transcription cofactor activity
0.37	GO:0005515	protein binding
0.37	GO:0003713	transcription coactivator activity
0.37	GO:0046872	metal ion binding
0.35	GO:0001786	phosphatidylserine binding

0.62	GO:0001772	immunological synapse
0.59	GO:0005769	early endosome
0.56	GO:0009986	cell surface
0.47	GO:0016592	mediator complex
0.43	GO:0030054	cell junction
0.42	GO:0070062	extracellular exosome
0.37	GO:0016604	nuclear body
0.36	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

sp|P0C0K7|EPHB6_RAT
Ephrin type-B receptor 6
Search

EPHB6

0.80	EPH receptor B6

0.83	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0001806	type IV hypersensitivity
0.75	GO:2000525	positive regulation of T cell costimulation
0.74	GO:0050798	activated T cell proliferation
0.71	GO:0050663	cytokine secretion
0.69	GO:0032092	positive regulation of protein binding
0.63	GO:0006468	protein phosphorylation
0.51	GO:0018212	peptidyl-tyrosine modification
0.36	GO:0070121	Kupffer's vesicle development

0.84	GO:0005003	ephrin receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005887	integral component of plasma membrane
0.62	GO:0009986	cell surface
0.34	GO:0070062	extracellular exosome

sp|P0C0L6|NPSR1_RAT
Neuropeptide S receptor
Search

NPSR1

0.97	Neuropeptide S receptor

0.77	GO:0007218	neuropeptide signaling pathway
0.61	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.38	GO:2000293	negative regulation of defecation
0.37	GO:1903999	negative regulation of eating behavior
0.37	GO:0060013	righting reflex
0.37	GO:0042755	eating behavior
0.36	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.35	GO:0003376	sphingosine-1-phosphate signaling pathway
0.33	GO:0038166	angiotensin-activated signaling pathway
0.33	GO:0097746	regulation of blood vessel diameter

0.79	GO:0008188	neuropeptide receptor activity
0.78	GO:0005000	vasopressin receptor activity
0.35	GO:0038036	sphingosine-1-phosphate receptor activity
0.35	GO:0008227	G-protein coupled amine receptor activity
0.33	GO:0004945	angiotensin type II receptor activity
0.33	GO:0016500	protein-hormone receptor activity
0.33	GO:0004997	thyrotropin-releasing hormone receptor activity

0.50	GO:0005887	integral component of plasma membrane
0.34	GO:0005737	cytoplasm
0.32	GO:0043227	membrane-bounded organelle
0.31	GO:0043229	intracellular organelle

sp|P0C0P7|NPS_RAT
Neuropeptide S
Search

NPS

0.97	Neuropeptide S

0.80	GO:0007218	neuropeptide signaling pathway
0.67	GO:0045760	positive regulation of action potential
0.66	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.66	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.64	GO:0008542	visual learning
0.48	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P0C0R5|PI3R4_RAT
Phosphoinositide 3-kinase regulatory subunit 4
Search

PIK3R4

0.91	Phosphoinositide 3-kinase regulatory subunit 4

0.62	GO:0006468	protein phosphorylation
0.60	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.57	GO:0042149	cellular response to glucose starvation
0.56	GO:0032801	receptor catabolic process
0.55	GO:0032465	regulation of cytokinesis
0.49	GO:0030242	autophagy of peroxisome
0.49	GO:0006623	protein targeting to vacuole
0.48	GO:0045324	late endosome to vacuole transport
0.47	GO:0016236	macroautophagy
0.36	GO:0034162	toll-like receptor 9 signaling pathway

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005515	protein binding

0.58	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.58	GO:0005770	late endosome
0.55	GO:0005930	axoneme
0.51	GO:0015630	microtubule cytoskeleton
0.50	GO:0071561	nucleus-vacuole junction
0.46	GO:0005643	nuclear pore
0.41	GO:0005776	autophagosome
0.36	GO:0030670	phagocytic vesicle membrane
0.34	GO:0005829	cytosol

0.36	EC:2.7.1.137	GO:0016303
0.36	KEGG:R03362	GO:0016303

sp|P0C0S7|H2AZ_RAT
Histone H2A.Z
Search

sp|P0C0T0|LITAF_RAT
Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog
Search

LITAF

0.90	Lipopolysaccharide induced TNF factor

0.85	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.81	GO:0071222	cellular response to lipopolysaccharide
0.77	GO:0001817	regulation of cytokine production
0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.38	GO:0007165	signal transduction

0.85	GO:0050699	WW domain binding
0.79	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.38	GO:0004871	signal transducer activity

0.87	GO:0098560	cytoplasmic side of late endosome membrane
0.87	GO:0098559	cytoplasmic side of early endosome membrane
0.86	GO:0098574	cytoplasmic side of lysosomal membrane
0.75	GO:0009898	cytoplasmic side of plasma membrane
0.70	GO:0005794	Golgi apparatus
0.69	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P0C0T2|ANKS6_RAT
Ankyrin repeat and SAM domain-containing protein 6
Search

ANKS6

0.92	Ankyrin repeat and sterile alpha motif domain containing 6

0.72	GO:0007368	determination of left/right symmetry
0.68	GO:0007507	heart development
0.50	GO:0048793	pronephros development
0.38	GO:0006414	translational elongation
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.55	GO:0042803	protein homodimerization activity
0.38	GO:0003746	translation elongation factor activity
0.36	GO:0008270	zinc ion binding
0.36	GO:0003700	DNA binding transcription factor activity

0.76	GO:0005929	cilium
0.47	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus

sp|P0C0W8|GP139_RAT
Probable G-protein coupled receptor 139
Search

GPR139

0.94	G-protein coupled receptor 139

0.74	GO:0007218	neuropeptide signaling pathway
0.59	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway

0.75	GO:0008188	neuropeptide receptor activity
0.50	GO:0046983	protein dimerization activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P0C152|MKS3_RAT
Meckelin
Search

TMEM67

0.95	Transmembrane protein 67

0.85	GO:0010826	negative regulation of centrosome duplication
0.80	GO:0060271	cilium assembly
0.57	GO:0030433	ubiquitin-dependent ERAD pathway
0.45	GO:0060028	convergent extension involved in axis elongation
0.44	GO:0060027	convergent extension involved in gastrulation
0.43	GO:0003341	cilium movement
0.38	GO:0048754	branching morphogenesis of an epithelial tube
0.38	GO:0007368	determination of left/right symmetry
0.37	GO:0007507	heart development
0.37	GO:1902857	positive regulation of non-motile cilium assembly

0.61	GO:0031005	filamin binding
0.51	GO:0051082	unfolded protein binding
0.36	GO:0051787	misfolded protein binding
0.32	GO:0004721	phosphoprotein phosphatase activity
0.31	GO:0046872	metal ion binding

0.85	GO:0036038	MKS complex
0.59	GO:0060170	ciliary membrane
0.55	GO:0005813	centrosome
0.54	GO:0030659	cytoplasmic vesicle membrane
0.52	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005930	axoneme
0.30	GO:0016021	integral component of membrane

0.32

EC:3.1.3.16

GO:0004721

sp|P0C169|H2A1C_RAT
Histone H2A type 1-C
Search

0.97	Histone H2A type 1-C

0.57	GO:0006342	chromatin silencing
0.48	GO:0008285	negative regulation of cell proliferation
0.44	GO:0031498	chromatin disassembly
0.44	GO:0032986	protein-DNA complex disassembly
0.44	GO:0070914	UV-damage excision repair
0.42	GO:0034728	nucleosome organization
0.34	GO:0031497	chromatin assembly
0.34	GO:0065004	protein-DNA complex assembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.37	GO:0019899	enzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.40	GO:0070062	extracellular exosome

sp|P0C170|H2A1E_RAT
Histone H2A type 1-E
Search

0.97	Histone H2A type 1-E

0.57	GO:0006342	chromatin silencing
0.49	GO:0008285	negative regulation of cell proliferation
0.43	GO:0031498	chromatin disassembly
0.43	GO:0032986	protein-DNA complex disassembly
0.43	GO:0070914	UV-damage excision repair
0.42	GO:0034728	nucleosome organization
0.35	GO:0031497	chromatin assembly
0.35	GO:0065004	protein-DNA complex assembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.37	GO:0019899	enzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.40	GO:0070062	extracellular exosome

sp|P0C172|TIP39_RAT
Tuberoinfundibular peptide of 39 residues
Search

PTH2

0.97	Tuberoinfundibular peptide of 39 residues

0.80	GO:0007218	neuropeptide signaling pathway
0.44	GO:0006171	cAMP biosynthetic process
0.40	GO:0010469	regulation of receptor activity

0.42	GO:0005102	receptor binding
0.40	GO:0030545	receptor regulator activity

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P0C1G7|WBP1L_RAT
WW domain binding protein 1-like
Search

WBP1L

0.97	Outcome predictor in acute leukemia 1

0.33

GO:0034220

ion transmembrane transport

0.33	GO:0005515	protein binding
0.33	GO:0015075	ion transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|P0C1G9|SOX11_RAT
Transcription factor SOX-11
Search

SOX11

0.96	SRY (Sex determining region Y)-box

0.56	GO:0060253	negative regulation of glial cell proliferation
0.56	GO:0061386	closure of optic fissure
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:2000648	positive regulation of stem cell proliferation
0.54	GO:2001109	regulation of lens epithelial cell proliferation
0.54	GO:0045669	positive regulation of osteoblast differentiation
0.54	GO:0072395	signal transduction involved in cell cycle checkpoint
0.54	GO:0050672	negative regulation of lymphocyte proliferation

0.59	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0001105	RNA polymerase II transcription coactivator activity
0.50	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0008135	translation factor activity, RNA binding
0.37	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.33	GO:0005667	transcription factor complex
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

sp|P0C1Q3|PCAT2_RAT
Lysophosphatidylcholine acyltransferase 2
Search

LPCAT2

0.96	LOW QUALITY PROTEIN: lysophosphatidylcholine acyltransferase 2

0.62	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.58	GO:0006663	platelet activating factor biosynthetic process
0.46	GO:0061024	membrane organization
0.40	GO:2001246	negative regulation of phosphatidylcholine biosynthetic process
0.39	GO:0043129	surfactant homeostasis
0.38	GO:0060041	retina development in camera-type eye
0.38	GO:0045732	positive regulation of protein catabolic process
0.33	GO:0006508	proteolysis

0.69	GO:0005509	calcium ion binding
0.63	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.57	GO:0005811	lipid droplet
0.51	GO:0005795	Golgi stack
0.51	GO:0005783	endoplasmic reticulum
0.38	GO:0000139	Golgi membrane
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

0.63

GO:0016746

sp|P0C1S9|DGLB_RAT
Sn1-specific diacylglycerol lipase beta
Search

DAGLB

0.95	Diacylglycerol lipase beta

0.61	GO:0006629	lipid metabolic process
0.57	GO:0007405	neuroblast proliferation
0.57	GO:0006690	icosanoid metabolic process
0.52	GO:0042136	neurotransmitter biosynthetic process
0.47	GO:0032787	monocarboxylic acid metabolic process
0.36	GO:1901575	organic substance catabolic process

0.50	GO:0016787	hydrolase activity
0.34	GO:0046872	metal ion binding

0.45	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.38	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016787

sp|P0C1T0|MMEL1_RAT
Membrane metallo-endopeptidase-like 1
Search

MMEL1

0.94	Membrane metalloendopeptidase like 1

0.57	GO:0006508	proteolysis
0.45	GO:0071492	cellular response to UV-A
0.45	GO:0071493	cellular response to UV-B
0.45	GO:0050435	amyloid-beta metabolic process
0.44	GO:0046449	creatinine metabolic process
0.44	GO:0090399	replicative senescence
0.44	GO:0019233	sensory perception of pain
0.43	GO:0001822	kidney development
0.42	GO:0071345	cellular response to cytokine stimulus

0.66	GO:0004222	metalloendopeptidase activity
0.39	GO:0008238	exopeptidase activity
0.39	GO:0008270	zinc ion binding
0.35	GO:0042277	peptide binding

0.43	GO:0044306	neuron projection terminus
0.43	GO:0005903	brush border
0.43	GO:0008021	synaptic vesicle
0.42	GO:0030425	dendrite
0.42	GO:0030424	axon
0.36	GO:0005886	plasma membrane
0.36	GO:0005576	extracellular region
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.66

GO:0004222

sp|P0C1X8|AAK1_RAT
AP2-associated protein kinase 1
Search

AAK1

0.89	AP2-associated protein kinase 1

0.67	GO:2000369	regulation of clathrin-dependent endocytosis
0.65	GO:0045747	positive regulation of Notch signaling pathway
0.63	GO:0006468	protein phosphorylation
0.61	GO:0050821	protein stabilization
0.57	GO:0032880	regulation of protein localization
0.42	GO:0006897	endocytosis
0.35	GO:0061024	membrane organization

0.69	GO:0035612	AP-2 adaptor complex binding
0.65	GO:0005112	Notch binding
0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0043195	terminal bouton
0.45	GO:0005905	clathrin-coated pit
0.45	GO:0031252	cell leading edge
0.44	GO:0019897	extrinsic component of plasma membrane
0.43	GO:0030136	clathrin-coated vesicle
0.38	GO:0071439	clathrin complex
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P0C1X9|LAIR1_RAT
Leukocyte-associated immunoglobulin-like receptor 1
Search

LAIR1

0.82	Leukocyte-associated immunoglobulin-like receptor 1

0.39	GO:0043312	neutrophil degranulation
0.38	GO:0002250	adaptive immune response
0.36	GO:0050776	regulation of immune response

0.35

GO:0005515

protein binding

0.48	GO:0070062	extracellular exosome
0.41	GO:0005886	plasma membrane
0.39	GO:0035579	specific granule membrane
0.39	GO:0070821	tertiary granule membrane
0.30	GO:0044425	membrane part

sp|P0C219|SLMAP_RAT
Sarcolemmal membrane-associated protein
Search

SLMAP

0.87	Sarcolemma associated protein (Fragment)

0.83	GO:0006936	muscle contraction
0.76	GO:1905150	regulation of voltage-gated sodium channel activity
0.74	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential
0.67	GO:0072659	protein localization to plasma membrane

0.52	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P0C279|CPEB1_RAT
Cytoplasmic polyadenylation element-binding protein 1
Search

CPEB1

0.97	Cytoplasmic polyadenylation element-binding protein 1

0.71	GO:0006417	regulation of translation
0.44	GO:0034249	negative regulation of cellular amide metabolic process
0.43	GO:0032269	negative regulation of cellular protein metabolic process
0.43	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.42	GO:0071456	cellular response to hypoxia
0.42	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0032869	cellular response to insulin stimulus
0.42	GO:0010629	negative regulation of gene expression
0.39	GO:0006397	mRNA processing
0.38	GO:0006518	peptide metabolic process

0.82	GO:0003730	mRNA 3'-UTR binding
0.81	GO:0045182	translation regulator activity
0.43	GO:0017091	AU-rich element binding
0.41	GO:0043022	ribosome binding
0.40	GO:0008135	translation factor activity, RNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.46	GO:1990124	messenger ribonucleoprotein complex
0.43	GO:0043005	neuron projection
0.43	GO:0045202	synapse
0.40	GO:0005634	nucleus
0.39	GO:0000932	P-body
0.38	GO:0036477	somatodendritic compartment
0.38	GO:0098590	plasma membrane region
0.38	GO:0005819	spindle
0.38	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0030054	cell junction

sp|P0C2B9|RM42_RAT
28S ribosomal protein L42, mitochondrial
Search

MRPL42

0.96	Mitochondrial ribosomal protein L42

0.38	GO:0070126	mitochondrial translational termination
0.37	GO:0070125	mitochondrial translational elongation
0.35	GO:0046426	negative regulation of JAK-STAT cascade
0.34	GO:0001558	regulation of cell growth
0.34	GO:0016567	protein ubiquitination
0.33	GO:0006886	intracellular protein transport
0.33	GO:0035556	intracellular signal transduction

0.36	GO:0003723	RNA binding
0.35	GO:0008269	JAK pathway signal transduction adaptor activity
0.35	GO:0005159	insulin-like growth factor receptor binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0008536	Ran GTPase binding

0.61	GO:0005840	ribosome
0.56	GO:0005759	mitochondrial matrix
0.45	GO:0005886	plasma membrane
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus

sp|P0C2C0|RM22_RAT
39S ribosomal protein L22, mitochondrial
Search

MRPL22

0.94	Mitochondrial ribosomal protein L22

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding

0.71	GO:0015934	large ribosomal subunit
0.54	GO:0005761	mitochondrial ribosome
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C2C1|RM30_RAT
39S ribosomal protein L30, mitochondrial
Search

MRPL30

0.94	Mitochondrial ribosomal protein L30

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0043624	cellular protein complex disassembly

0.64

GO:0003735

structural constituent of ribosome

0.71	GO:0015934	large ribosomal subunit
0.45	GO:0005761	mitochondrial ribosome
0.36	GO:0019866	organelle inner membrane
0.36	GO:0031966	mitochondrial membrane

sp|P0C2C4|RM10_RAT
39S ribosomal protein L10, mitochondrial
Search

MRPL10

0.97	Mitochondrial ribosomal protein L10

0.64	GO:0042254	ribosome biogenesis
0.50	GO:0032543	mitochondrial translation
0.35	GO:0006415	translational termination
0.35	GO:0006869	lipid transport
0.34	GO:0006414	translational elongation
0.33	GO:0006508	proteolysis

0.43	GO:0003735	structural constituent of ribosome
0.35	GO:0016805	dipeptidase activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.58	GO:0005762	mitochondrial large ribosomal subunit
0.51	GO:0005654	nucleoplasm
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

0.35

EC:3.4.13

GO:0016805

sp|P0C2N5|KMT5B_RAT
Histone-lysine N-methyltransferase KMT5B
Search

KMT5B

0.51	Histone-lysine N-methyltransferase

0.85	GO:0034773	histone H4-K20 trimethylation
0.41	GO:0040014	regulation of multicellular organism growth
0.41	GO:0007517	muscle organ development
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.85	GO:0042799	histone methyltransferase activity (H4-K20 specific)
0.34	GO:0005515	protein binding

0.54	GO:0000780	condensed nuclear chromosome, centromeric region
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P0C2N6|KMT5C_RAT
Histone-lysine N-methyltransferase KMT5C
Search

KMT5C

0.45	Histone-lysine N-methyltransferase

0.85	GO:0034773	histone H4-K20 trimethylation
0.43	GO:0040014	regulation of multicellular organism growth
0.38	GO:0007517	muscle organ development
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.85	GO:0042799	histone methyltransferase activity (H4-K20 specific)
0.34	GO:0005515	protein binding

0.57	GO:0000780	condensed nuclear chromosome, centromeric region
0.55	GO:0005721	pericentric heterochromatin
0.55	GO:0005720	nuclear heterochromatin
0.49	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P0C2X9|AL4A1_RAT
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
Search

ALDH4A1

0.59	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.78	GO:0010133	proline catabolic process to glutamate
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0007005	mitochondrion organization
0.36	GO:0019470	4-hydroxyproline catabolic process
0.35	GO:0046487	glyoxylate metabolic process
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006091	generation of precursor metabolites and energy

0.79	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity
0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.47	GO:0042802	identical protein binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0009055	electron transfer activity

0.43	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.5.1.12

GO:0003842

sp|P0C546|S2542_RAT
Mitochondrial coenzyme A transporter SLC25A42
Search

SLC25A42

0.95	Mitochondrial coenzyme A transporter SLC25A42

0.60	GO:0080121	AMP transport
0.59	GO:0071106	adenosine 3',5'-bisphosphate transmembrane transport
0.59	GO:0015880	coenzyme A transport
0.57	GO:0015866	ADP transport
0.55	GO:0015867	ATP transport
0.49	GO:0098656	anion transmembrane transport
0.48	GO:0006839	mitochondrial transport
0.34	GO:0007006	mitochondrial membrane organization

0.60	GO:0080122	AMP transmembrane transporter activity
0.59	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity
0.59	GO:0043262	adenosine-diphosphatase activity
0.57	GO:0015217	ADP transmembrane transporter activity
0.55	GO:0005347	ATP transmembrane transporter activity
0.54	GO:0051185	coenzyme transmembrane transporter activity
0.35	GO:0015297	antiporter activity

0.57	GO:0031966	mitochondrial membrane
0.57	GO:0019866	organelle inner membrane
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P0C548|PLPL2_RAT
Patatin-like phospholipase domain-containing protein 2
Search

PNPLA2

0.94	Patatin like phospholipase domain containing 2

0.81	GO:0010898	positive regulation of triglyceride catabolic process
0.72	GO:0016042	lipid catabolic process
0.59	GO:0010891	negative regulation of sequestering of triglyceride
0.56	GO:0034389	lipid particle organization
0.55	GO:0006641	triglyceride metabolic process
0.54	GO:0019915	lipid storage
0.47	GO:0055088	lipid homeostasis
0.46	GO:0044248	cellular catabolic process
0.37	GO:0001889	liver development
0.36	GO:0036155	acylglycerol acyl-chain remodeling

0.74	GO:0004806	triglyceride lipase activity
0.35	GO:0005515	protein binding
0.35	GO:0016411	acylglycerol O-acyltransferase activity

0.56	GO:0005811	lipid droplet
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005886	plasma membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.74

EC:3.1.1.3

GO:0004806

sp|P0C588|CNNM4_RAT
Metal transporter CNNM4
Search

CNNM4

0.91	Cyclin and CBS domain divalent metal cation transport mediator 4

0.72	GO:0010960	magnesium ion homeostasis
0.67	GO:0070166	enamel mineralization
0.64	GO:1903830	magnesium ion transmembrane transport
0.59	GO:0035725	sodium ion transmembrane transport
0.38	GO:0060041	retina development in camera-type eye

0.64	GO:0015095	magnesium ion transmembrane transporter activity
0.57	GO:0015081	sodium ion transmembrane transporter activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0016323	basolateral plasma membrane
0.49	GO:0043234	protein complex
0.40	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|P0C595|DUPD1_RAT
Dual specificity phosphatase DUPD1
Search

DUPD1

0.97	Dual specificity phosphatase and pro isomerase domain containing 1

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:1902310	positive regulation of peptidyl-serine dephosphorylation
0.34	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.33	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.33	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0045785	positive regulation of cell adhesion
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.73	GO:0004725	protein tyrosine phosphatase activity
0.52	GO:0042803	protein homodimerization activity
0.33	GO:0001102	RNA polymerase II activating transcription factor binding
0.33	GO:0002039	p53 binding
0.33	GO:0004647	phosphoserine phosphatase activity
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0043234	protein complex
0.37	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0012505	endomembrane system
0.32	GO:0005634	nucleus

0.78

GO:0008138

sp|P0C5E3|PALLD_RAT
Palladin (Fragment)
Search

PALLD

0.85	Palladin, cytoskeletal associated protein (Fragment)

0.77	GO:0016477	cell migration
0.74	GO:0030036	actin cytoskeleton organization
0.57	GO:0003334	keratinocyte development
0.55	GO:0003382	epithelial cell morphogenesis
0.39	GO:0071803	positive regulation of podosome assembly
0.39	GO:0060707	trophoblast giant cell differentiation
0.38	GO:0031529	ruffle organization
0.38	GO:0071456	cellular response to hypoxia
0.37	GO:0042060	wound healing
0.37	GO:0031175	neuron projection development

0.36

GO:0003779

actin binding

0.51	GO:0005884	actin filament
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.39	GO:0044295	axonal growth cone
0.38	GO:0002102	podosome
0.38	GO:0001725	stress fiber
0.38	GO:0030175	filopodium
0.38	GO:0030018	Z disc
0.38	GO:0001726	ruffle

sp|P0C5E9|CRBS_RAT
Beta-crystallin S
Search

CRYGS

0.97	Crystallin gamma S

0.80	GO:0002088	lens development in camera-type eye
0.74	GO:0002009	morphogenesis of an epithelium

0.85	GO:0005212	structural constituent of eye lens
0.35	GO:0005515	protein binding

0.30

GO:0044425

membrane part

sp|P0C5H6|TUTLA_RAT
Protein turtle homolog A
Search

IGSF9

0.41	MAM domain-containing glycosylphosphatidylinositol anchor protein 2

0.59	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.58	GO:0016358	dendrite development
0.58	GO:0050807	regulation of synapse organization
0.50	GO:0097151	positive regulation of inhibitory postsynaptic potential
0.41	GO:0007399	nervous system development
0.39	GO:0030154	cell differentiation
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation

0.61	GO:0098632	cell-cell adhesion mediator activity
0.45	GO:0019900	kinase binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.66	GO:0060077	inhibitory synapse
0.61	GO:0030425	dendrite
0.56	GO:0030424	axon
0.46	GO:0043025	neuronal cell body
0.41	GO:0030054	cell junction
0.36	GO:0005886	plasma membrane
0.36	GO:0014069	postsynaptic density
0.30	GO:0016021	integral component of membrane

0.34

GO:0004725

sp|P0C5H9|MANF_RAT
Mesencephalic astrocyte-derived neurotrophic factor
Search

MANF

0.97	Mesencephalic astrocyte-derived neurotrophic factor

0.75	GO:0071542	dopaminergic neuron differentiation
0.61	GO:0031175	neuron projection development
0.47	GO:0010469	regulation of receptor activity
0.46	GO:0006986	response to unfolded protein
0.46	GO:0002014	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure
0.41	GO:0006508	proteolysis
0.41	GO:0007264	small GTPase mediated signal transduction
0.39	GO:0002576	platelet degranulation
0.39	GO:0006886	intracellular protein transport

0.48	GO:0008083	growth factor activity
0.45	GO:0004222	metalloendopeptidase activity
0.45	GO:0005509	calcium ion binding
0.42	GO:0008270	zinc ion binding
0.41	GO:0005085	guanyl-nucleotide exchange factor activity
0.39	GO:0003723	RNA binding

0.59	GO:0005615	extracellular space
0.59	GO:0005783	endoplasmic reticulum
0.43	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.45

GO:0004222

sp|P0C5I0|CDNF_RAT
Cerebral dopamine neurotrophic factor
Search

CDNF

0.96	Mesencephalic astrocyte derived neurotrophic factor

0.82	GO:0071542	dopaminergic neuron differentiation
0.69	GO:0031175	neuron projection development
0.49	GO:0010469	regulation of receptor activity
0.44	GO:0006986	response to unfolded protein
0.44	GO:0002014	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure
0.38	GO:0002576	platelet degranulation
0.36	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0006886	intracellular protein transport

0.50	GO:0008083	growth factor activity
0.38	GO:0003723	RNA binding
0.36	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0005509	calcium ion binding

0.66	GO:0005615	extracellular space
0.64	GO:0005783	endoplasmic reticulum
0.42	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P0C5J2|B9D1_RAT
B9 domain-containing protein 1
Search

B9D1

0.96	B9 domain-containing protein 1

0.84	GO:0060563	neuroepithelial cell differentiation
0.84	GO:0042733	embryonic digit morphogenesis
0.84	GO:0007224	smoothened signaling pathway
0.80	GO:0060271	cilium assembly
0.79	GO:0043010	camera-type eye development
0.78	GO:0001944	vasculature development
0.76	GO:0001701	in utero embryonic development
0.73	GO:0032880	regulation of protein localization
0.40	GO:0140056	organelle localization by membrane tethering

0.86	GO:0008158	hedgehog receptor activity
0.37	GO:0005515	protein binding

0.85	GO:0036038	MKS complex
0.82	GO:0036064	ciliary basal body
0.78	GO:0005813	centrosome
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0C5J3|B9D2_RAT
B9 domain-containing protein 2
Search

B9D2

0.93	Transforming growth factor beta 1

0.75	GO:0060271	cilium assembly
0.60	GO:0036372	opsin transport
0.56	GO:0001736	establishment of planar polarity
0.53	GO:0007163	establishment or maintenance of cell polarity
0.45	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.45	GO:1901664	regulation of NAD+ ADP-ribosyltransferase activity
0.45	GO:0043932	ossification involved in bone remodeling
0.45	GO:0048298	positive regulation of isotype switching to IgA isotypes
0.44	GO:0007182	common-partner SMAD protein phosphorylation
0.44	GO:0010936	negative regulation of macrophage cytokine production

0.71	GO:0043015	gamma-tubulin binding
0.45	GO:0034714	type III transforming growth factor beta receptor binding
0.44	GO:0005114	type II transforming growth factor beta receptor binding
0.44	GO:0034713	type I transforming growth factor beta receptor binding
0.43	GO:0003823	antigen binding
0.42	GO:0008083	growth factor activity
0.34	GO:0004190	aspartic-type endopeptidase activity

0.76	GO:0036038	MKS complex
0.74	GO:0036064	ciliary basal body
0.69	GO:0005813	centrosome
0.43	GO:0072562	blood microparticle
0.42	GO:0005634	nucleus
0.41	GO:0009986	cell surface
0.38	GO:0005737	cytoplasm
0.37	GO:0044292	dendrite terminus
0.30	GO:0016020	membrane

0.34

GO:0004190

sp|P0C5J5|WFKN1_RAT
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1
Search

WFIKKN2

0.97	Growth and differentiation factor-associated serum protein 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.68	GO:1900116	extracellular negative regulation of signal transduction
0.66	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.66	GO:0043392	negative regulation of DNA binding
0.66	GO:0060021	palate development
0.66	GO:0048747	muscle fiber development
0.66	GO:0032091	negative regulation of protein binding
0.62	GO:0001501	skeletal system development
0.54	GO:0007179	transforming growth factor beta receptor signaling pathway
0.33	GO:0035556	intracellular signal transduction

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.69	GO:0050431	transforming growth factor beta binding
0.69	GO:0048019	receptor antagonist activity
0.44	GO:0008191	metalloendopeptidase inhibitor activity
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0140096	catalytic activity, acting on a protein

0.66	GO:0005576	extracellular region
0.32	GO:0005622	intracellular
0.32	GO:0030054	cell junction
0.31	GO:0005887	integral component of plasma membrane

0.32

GO:0016773

sp|P0C5J9|SHKB1_RAT
SH3KBP1-binding protein 1
Search

SHKBP1

0.72	SH3KBP1-binding protein 1

0.78	GO:0051260	protein homooligomerization
0.61	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.38	GO:0032958	inositol phosphate biosynthetic process
0.34	GO:0016310	phosphorylation

0.41	GO:0005515	protein binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0016301	kinase activity

0.52

GO:0005764

lysosome

sp|P0C5W1|MAP1S_RAT
Microtubule-associated protein 1S
Search

MAP1S

0.95	Microtubule-associated protein 1S

0.77	GO:0006915	apoptotic process
0.76	GO:0000226	microtubule cytoskeleton organization
0.69	GO:0010848	regulation of chromatin disassembly
0.60	GO:0048812	neuron projection morphogenesis
0.52	GO:0007420	brain development
0.38	GO:0047497	mitochondrion transport along microtubule
0.36	GO:0006914	autophagy

0.78	GO:0051015	actin filament binding
0.74	GO:0008017	microtubule binding
0.63	GO:0048487	beta-tubulin binding
0.49	GO:0042802	identical protein binding
0.45	GO:0003677	DNA binding
0.40	GO:0004536	deoxyribonuclease activity

0.73	GO:0005874	microtubule
0.60	GO:0048471	perinuclear region of cytoplasm
0.58	GO:0045202	synapse
0.55	GO:0030054	cell junction
0.55	GO:0005730	nucleolus
0.54	GO:0042995	cell projection
0.54	GO:0005829	cytosol
0.52	GO:0043025	neuronal cell body
0.46	GO:0005819	spindle

sp|P0C5X8|TTYH1_RAT
Protein tweety homolog 1
Search

sp|P0C5Y8|ALS2_RAT
Alsin
Search

ALS2

0.93	Amyotrophic lateral sclerosis 2 (Juvenile)

0.75	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.61	GO:0051036	regulation of endosome size
0.60	GO:0001881	receptor recycling
0.60	GO:0001662	behavioral fear response
0.60	GO:0035249	synaptic transmission, glutamatergic
0.58	GO:0007528	neuromuscular junction development
0.58	GO:0007032	endosome organization
0.56	GO:0007626	locomotory behavior
0.55	GO:0048812	neuron projection morphogenesis

0.75	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.59	GO:0048365	Rac GTPase binding
0.58	GO:0043539	protein serine/threonine kinase activator activity
0.58	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.53	GO:0042803	protein homodimerization activity
0.35	GO:0005096	GTPase activator activity

0.58	GO:0043197	dendritic spine
0.57	GO:0014069	postsynaptic density
0.57	GO:0001726	ruffle
0.57	GO:0030027	lamellipodium
0.56	GO:0005769	early endosome
0.55	GO:0005813	centrosome
0.50	GO:0005829	cytosol
0.45	GO:0043234	protein complex
0.40	GO:0030426	growth cone
0.39	GO:0043025	neuronal cell body

sp|P0C606|SGF29_RAT
SAGA-associated factor 29
Search

SGF29

0.85	Coiled-coil domain-containing protein 101

0.80	GO:0000124	SAGA complex
0.45	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex

sp|P0C627|UBX2B_RAT
UBX domain-containing protein 2B
Search

UBXN2B

0.97	UBX domain-containing protein 2B

0.78	GO:0031468	nuclear envelope reassembly
0.74	GO:0000045	autophagosome assembly
0.74	GO:0007030	Golgi organization
0.70	GO:0043666	regulation of phosphoprotein phosphatase activity
0.69	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.62	GO:0061025	membrane fusion
0.35	GO:0051028	mRNA transport

0.73	GO:0043130	ubiquitin binding
0.71	GO:0019888	protein phosphatase regulator activity
0.45	GO:0051117	ATPase binding
0.44	GO:0008289	lipid binding
0.36	GO:0043168	anion binding

0.68	GO:0005829	cytosol
0.63	GO:0045111	intermediate filament cytoskeleton
0.61	GO:0005634	nucleus
0.55	GO:0031974	membrane-enclosed lumen
0.51	GO:0005794	Golgi apparatus
0.49	GO:0044446	intracellular organelle part
0.48	GO:1990730	VCP-NSFL1C complex
0.47	GO:0005886	plasma membrane
0.46	GO:0005783	endoplasmic reticulum
0.41	GO:0005694	chromosome

sp|P0C643|GRP2_RAT
RAS guanyl-releasing protein 2
Search

RASGRP2

0.97	RAS guanyl releasing protein 2 (calcium and DAG-regulated)

0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.52	GO:0071277	cellular response to calcium ion
0.34	GO:0001558	regulation of cell growth
0.33	GO:0000165	MAPK cascade
0.33	GO:0005975	carbohydrate metabolic process

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.69	GO:0005509	calcium ion binding
0.58	GO:0005096	GTPase activator activity
0.41	GO:0019900	kinase binding
0.41	GO:0017016	Ras GTPase binding
0.36	GO:0019992	diacylglycerol binding
0.35	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.35	GO:0102499	SHG alpha-glucan phosphorylase activity
0.35	GO:0008184	glycogen phosphorylase activity
0.34	GO:0030170	pyridoxal phosphate binding

0.46	GO:0005829	cytosol
0.43	GO:0032045	guanyl-nucleotide exchange factor complex
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005886	plasma membrane
0.39	GO:0043005	neuron projection
0.39	GO:0001726	ruffle
0.39	GO:0045202	synapse
0.39	GO:0030054	cell junction
0.38	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

sp|P0C644|VIP1_RAT
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
Search

PPIP5K1

0.90	Diphosphoinositol pentakisphosphate kinase 1

0.59	GO:0006020	inositol metabolic process
0.57	GO:0016310	phosphorylation
0.48	GO:0032958	inositol phosphate biosynthetic process

0.85	GO:0000829	inositol heptakisphosphate kinase activity
0.67	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity
0.67	GO:0000828	inositol hexakisphosphate kinase activity
0.66	GO:0000827	inositol-1,3,4,5,6-pentakisphosphate kinase activity

0.53	GO:0005829	cytosol
0.53	GO:0005654	nucleoplasm

0.67

EC:2.7.4.24

GO:0033857

sp|P0C6B1|S35E1_RAT
Solute carrier family 35 member E1
Search

SLC35E1

0.95	Solute carrier family 35 member E1

0.50	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

sp|P0C6B3|PTCRA_RAT
Pre T-cell antigen receptor alpha
Search

PTCRA

0.97	Pre T-cell antigen receptor alpha

0.78

GO:0070244

negative regulation of thymocyte apoptotic process

0.46

GO:0005515

protein binding

0.43	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P0C6B8|SVEP1_RAT
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1
Search

SVEP1

0.62	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

0.53	GO:0001945	lymph vessel development
0.31	GO:0007155	cell adhesion

0.70	GO:0005509	calcium ion binding
0.51	GO:0003682	chromatin binding

0.49	GO:0005615	extracellular space
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0C6C0|SPKAP_RAT
A-kinase anchor protein SPHKAP
Search

SPHKAP

0.90	A-kinase anchor protein SPHKAP

0.57	GO:0016310	phosphorylation
0.35	GO:0010738	regulation of protein kinase A signaling

0.60	GO:0016301	kinase activity
0.38	GO:0051018	protein kinase A binding

0.33	GO:0005739	mitochondrion
0.30	GO:0070062	extracellular exosome
0.30	GO:0044422	organelle part
0.30	GO:0043292	contractile fiber

sp|P0C6P5|ARG28_RAT
Rho guanine nucleotide exchange factor 28
Search

ARHGEF28

0.77	Rho-guanine nucleotide exchange factor

0.77	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.61	GO:0035556	intracellular signal transduction
0.38	GO:0060052	neurofilament cytoskeleton organization
0.37	GO:0021955	central nervous system neuron axonogenesis
0.36	GO:0048013	ephrin receptor signaling pathway
0.32	GO:0006468	protein phosphorylation

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.51	GO:0046872	metal ion binding
0.35	GO:0003723	RNA binding
0.33	GO:0004691	cAMP-dependent protein kinase activity

0.44	GO:0005622	intracellular
0.35	GO:0005886	plasma membrane

0.33

EC:2.7.11.11

GO:0004691

sp|P0C6P6|TYY2_RAT
Transcription factor YY2
Search

0.93	Transcriptional repressor protein YY1

0.44	GO:0010628	positive regulation of gene expression
0.42	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.42	GO:0032688	negative regulation of interferon-beta production
0.42	GO:0010225	response to UV-C
0.42	GO:0048513	animal organ development
0.41	GO:0034644	cellular response to UV
0.41	GO:0009952	anterior/posterior pattern specification
0.40	GO:0007283	spermatogenesis
0.40	GO:0000724	double-strand break repair via homologous recombination
0.39	GO:1903508	positive regulation of nucleic acid-templated transcription

0.51	GO:0003676	nucleic acid binding
0.41	GO:0046332	SMAD binding
0.41	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.41	GO:0031519	PcG protein complex
0.40	GO:0031011	Ino80 complex
0.39	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004222

sp|P0C6P7|FEM1B_RAT
Protein fem-1 homolog B
Search

FEM1B

0.97	Fem-1 homolog b (C. elegans)

0.87	GO:0060743	epithelial cell maturation involved in prostate gland development
0.86	GO:0060442	branching involved in prostate gland morphogenesis
0.86	GO:2000001	regulation of DNA damage checkpoint
0.85	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.81	GO:0051438	regulation of ubiquitin-protein transferase activity
0.73	GO:0016567	protein ubiquitination
0.50	GO:0006915	apoptotic process
0.40	GO:0043687	post-translational protein modification

0.86	GO:0005123	death receptor binding
0.72	GO:0004842	ubiquitin-protein transferase activity

0.69	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol

0.72

GO:0004842

sp|P0C6R4|IFFO2_RAT
Intermediate filament family orphan 2
Search

IFFO2

0.91	Intermediate filament family orphan 2

0.42	GO:0010133	proline catabolic process to glutamate
0.36	GO:0055114	oxidation-reduction process
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006364	rRNA processing
0.32	GO:0032259	methylation

0.59	GO:0005198	structural molecule activity
0.42	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity
0.40	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0042802	identical protein binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.32	GO:0003723	RNA binding

0.74	GO:0005882	intermediate filament
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.42

EC:1.5.1.12

GO:0003842

sp|P0C6S7|ANS1B_RAT
Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Search

ANKS1B

0.84	Ankyrin repeat and sterile alpha motif domain-containing protein 1B

0.86

GO:1900383

regulation of synaptic plasticity by receptor localization to synapse

0.57

GO:0046875

ephrin receptor binding

0.48	GO:0005829	cytosol
0.43	GO:0043231	intracellular membrane-bounded organelle
0.43	GO:0005886	plasma membrane
0.42	GO:0043197	dendritic spine
0.42	GO:0014069	postsynaptic density
0.40	GO:0030054	cell junction
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

sp|P0C6T3|PRR7_RAT
Proline-rich protein 7
Search

PRR7

0.97	Proline-rich protein 7

0.45	GO:0002250	adaptive immune response
0.39	GO:0030217	T cell differentiation
0.34	GO:0008359	regulation of bicoid mRNA localization
0.34	GO:0006468	protein phosphorylation
0.34	GO:0003002	regionalization
0.34	GO:0035295	tube development
0.34	GO:0008103	oocyte microtubule cytoskeleton polarization
0.34	GO:0030182	neuron differentiation
0.34	GO:0051716	cellular response to stimulus
0.34	GO:0007317	regulation of pole plasm oskar mRNA localization

0.37	GO:0004703	G-protein coupled receptor kinase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0003676	nucleic acid binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008144	drug binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0005199	structural constituent of cell wall
0.32	GO:0004871	signal transducer activity

0.44	GO:0030425	dendrite
0.44	GO:0045211	postsynaptic membrane
0.44	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0030054	cell junction
0.39	GO:0005634	nucleus
0.34	GO:0005703	polytene chromosome puff
0.33	GO:1905360	GTPase complex
0.32	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.32	GO:0098797	plasma membrane protein complex
0.30	GO:0016021	integral component of membrane

0.37

EC:2.7.11.16

GO:0004703

sp|P0C6Y7|PRDM9_RAT
Histone-lysine N-methyltransferase PRDM9
Search

0.67	Histone-lysine N-methyltransferase PRDM9

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.51	GO:0006311	meiotic gene conversion
0.51	GO:0010845	positive regulation of reciprocal meiotic recombination
0.44	GO:0032259	methylation
0.43	GO:0016570	histone modification
0.42	GO:0018205	peptidyl-lysine modification
0.42	GO:0008213	protein alkylation
0.36	GO:0007283	spermatogenesis

0.50	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.44	GO:0008168	methyltransferase activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0033971	hydroxyisourate hydrolase activity
0.34	GO:0005515	protein binding

0.58	GO:0005634	nucleus
0.38	GO:0005694	chromosome
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm

0.44	EC:2.1.1	GO:0008168
0.35	KEGG:R06601	GO:0033971

sp|P0C7J6|LRFN1_RAT
Leucine-rich repeat and fibronectin type III domain-containing protein 1
Search

LRFN1

0.86	Leucine-rich repeat and fibronectin type III domain-containing protein 1

0.50	GO:0007409	axonogenesis
0.36	GO:0007155	cell adhesion
0.35	GO:0007259	JAK-STAT cascade
0.34	GO:0050778	positive regulation of immune response
0.34	GO:0051607	defense response to virus
0.34	GO:0010469	regulation of receptor activity

0.35	GO:0005515	protein binding
0.34	GO:0030545	receptor regulator activity

0.54	GO:0009986	cell surface
0.48	GO:0005578	proteinaceous extracellular matrix
0.47	GO:0005615	extracellular space
0.41	GO:0045211	postsynaptic membrane
0.40	GO:0030054	cell junction
0.40	GO:0097458	neuron part
0.40	GO:0032279	asymmetric synapse
0.39	GO:0099572	postsynaptic specialization
0.36	GO:0120038	plasma membrane bounded cell projection part
0.32	GO:0005622	intracellular

sp|P0C7L8|PPR3E_RAT
Protein phosphatase 1 regulatory subunit 3E
Search

PPP1R3E

0.97	LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 3E

0.75	GO:0005977	glycogen metabolic process
0.61	GO:0005981	regulation of glycogen catabolic process
0.61	GO:0005979	regulation of glycogen biosynthetic process
0.52	GO:0006470	protein dephosphorylation

0.52

GO:0004721

phosphoprotein phosphatase activity

0.63

GO:0042587

glycogen granule

0.52

EC:3.1.3.16

GO:0004721

sp|P0C7N0|RWDD3_RAT
RWD domain-containing protein 3
Search

RWDD3

0.97	RWD domain-containing protein 3

0.88	GO:1902073	positive regulation of hypoxia-inducible factor-1alpha signaling pathway
0.86	GO:0033235	positive regulation of protein sumoylation
0.84	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.37

GO:0005515

protein binding

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

sp|P0C7N2|ERIC4_RAT
Glutamate-rich protein 4
Search

ERICH4

0.97	Glutamate-rich protein 4

sp|P0C865|MK07_RAT
Mitogen-activated protein kinase 7
Search

MAPK7

0.50	Mitogen-activated protein kinase

0.76	GO:0000165	MAPK cascade
0.65	GO:0070377	negative regulation of ERK5 cascade
0.63	GO:0071499	cellular response to laminar fluid shear stress
0.63	GO:0051534	negative regulation of NFAT protein import into nucleus
0.62	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.61	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.61	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.61	GO:2000352	negative regulation of endothelial cell apoptotic process
0.59	GO:0070301	cellular response to hydrogen peroxide
0.59	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress

0.78	GO:0004707	MAP kinase activity
0.61	GO:0051019	mitogen-activated protein kinase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.32	GO:0003677	DNA binding

0.59	GO:0016605	PML body
0.51	GO:0005829	cytosol
0.36	GO:0030128	clathrin coat of endocytic vesicle
0.30	GO:0016021	integral component of membrane

0.78	EC:2.7.11.24	GO:0004707
0.78	KEGG:R00162	GO:0004707

sp|P0C8E4|M3K7_RAT
Mitogen-activated protein kinase kinase kinase 7
Search

MAP3K7

0.94	Mitogen-activated protein kinase kinase kinase 7

0.84	GO:0000186	activation of MAPKK activity
0.79	GO:0000165	MAPK cascade
0.67	GO:0007252	I-kappaB phosphorylation
0.66	GO:0043507	positive regulation of JUN kinase activity
0.59	GO:0002726	positive regulation of T cell cytokine production
0.58	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.58	GO:0032743	positive regulation of interleukin-2 production
0.56	GO:0043966	histone H3 acetylation
0.56	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.56	GO:0000187	activation of MAPK activity

0.85	GO:0004709	MAP kinase kinase kinase activity
0.64	GO:0000287	magnesium ion binding
0.57	GO:0097110	scaffold protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042802	identical protein binding
0.36	GO:0004708	MAP kinase kinase activity

0.59	GO:0008385	IkappaB kinase complex
0.56	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.45	GO:0005886	plasma membrane
0.36	GO:0014069	postsynaptic density
0.35	GO:0010008	endosome membrane

0.85

EC:2.7.11 EC:2.7.11.25

GO:0004709

sp|P0C8N6|NEMP2_RAT
Nuclear envelope integral membrane protein 2
Search

NEMP2

0.95	Nuclear envelope integral membrane protein 2

0.54	GO:0005635	nuclear envelope
0.42	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P0C927|ASB14_RAT
Ankyrin repeat and SOCS box protein 14
Search

ASB14

0.97	Ankyrin repeat and SOCS box containing 14

0.66	GO:0016567	protein ubiquitination
0.61	GO:0035556	intracellular signal transduction
0.35	GO:0043687	post-translational protein modification

0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0004842	ubiquitin-protein transferase activity

0.46	GO:0000151	ubiquitin ligase complex
0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

0.45

GO:0004842

sp|P0CAX5|OPHN1_RAT
Oligophrenin-1
Search

OPHN1

0.94	Rho GTPase-activating protein 42

0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.56	GO:0045198	establishment of epithelial cell apical/basal polarity
0.56	GO:0021684	cerebellar granular layer formation
0.55	GO:0021895	cerebral cortex neuron differentiation
0.54	GO:0021533	cell differentiation in hindbrain
0.53	GO:0034329	cell junction assembly
0.53	GO:0051966	regulation of synaptic transmission, glutamatergic
0.53	GO:0048488	synaptic vesicle endocytosis
0.52	GO:1901799	negative regulation of proteasomal protein catabolic process

0.74	GO:0005096	GTPase activator activity
0.49	GO:0005543	phospholipid binding
0.47	GO:0003779	actin binding
0.40	GO:0035255	ionotropic glutamate receptor binding

0.53	GO:0043197	dendritic spine
0.52	GO:0043195	terminal bouton
0.47	GO:0015629	actin cytoskeleton
0.40	GO:0030054	cell junction
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0CB49|YLPM1_RAT
YLP motif-containing protein 1
Search

YLPM1

0.71	YLP motif-containing protein 1

0.50	GO:0032204	regulation of telomere maintenance
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0006351	transcription, DNA-templated

0.50	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0005515	protein binding
0.38	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0005829	cytosol
0.41	GO:0044446	intracellular organelle part

sp|P0CC09|H2A2A_RAT
Histone H2A type 2-A
Search

0.95	Histone H2A type 2-A

0.53	GO:0006342	chromatin silencing
0.35	GO:0006333	chromatin assembly or disassembly
0.35	GO:0034728	nucleosome organization
0.34	GO:0032986	protein-DNA complex disassembly
0.34	GO:0070914	UV-damage excision repair
0.34	GO:0065004	protein-DNA complex assembly
0.34	GO:0006323	DNA packaging

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.35	GO:0019899	enzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.39	GO:0070062	extracellular exosome

sp|P0CC10|LRC4B_RAT
Leucine-rich repeat-containing protein 4B
Search

LRRC4B

0.94	Leucine-rich repeat-containing protein 4

0.72	GO:0051960	regulation of nervous system development
0.67	GO:0050807	regulation of synapse organization
0.64	GO:0044089	positive regulation of cellular component biogenesis
0.63	GO:0051094	positive regulation of developmental process
0.63	GO:0051240	positive regulation of multicellular organismal process
0.61	GO:0051130	positive regulation of cellular component organization
0.57	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.55	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.53	GO:0048699	generation of neurons
0.51	GO:0046426	negative regulation of JAK-STAT cascade

0.50	GO:0004860	protein kinase inhibitor activity
0.48	GO:0005102	receptor binding
0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0050661	NADP binding
0.32	GO:0016491	oxidoreductase activity

0.56	GO:0044300	cerebellar mossy fiber
0.41	GO:0042734	presynaptic membrane
0.39	GO:0030054	cell junction
0.37	GO:0005737	cytoplasm
0.32	GO:0045211	postsynaptic membrane
0.31	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.32

EC:1

GO:0016491

sp|P0CD94|UQCC3_RAT
Ubiquinol-cytochrome-c reductase complex assembly factor 3
Search

UQCC3

0.90	Ubiquinol-cytochrome-c reductase complex assembly factor 3

0.84	GO:0017062	respiratory chain complex III assembly
0.84	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.81	GO:0033108	mitochondrial respiratory chain complex assembly
0.75	GO:0042407	cristae formation
0.66	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.49	GO:0006754	ATP biosynthetic process

0.80	GO:1901612	cardiolipin binding
0.78	GO:0070300	phosphatidic acid binding
0.39	GO:0016301	kinase activity

0.73	GO:0005750	mitochondrial respiratory chain complex III
0.71	GO:0031305	integral component of mitochondrial inner membrane

sp|P0CD95|CQ067_RAT
Uncharacterized protein C17orf67 homolog
Search

0.43

GO:0005515

protein binding

0.55	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P0CD96|OCC1_RAT
Overexpressed in colon carcinoma 1 protein homolog
Search

0.97	Overexpressed in colon carcinoma 1 protein homolog

sp|P0CE43|GRB10_RAT
Growth factor receptor-bound protein 10
Search

GRB10

0.92	Growth factor receptor-bound protein 10

0.80	GO:0046627	negative regulation of insulin receptor signaling pathway
0.70	GO:0009967	positive regulation of signal transduction
0.60	GO:0007165	signal transduction
0.56	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.55	GO:0046325	negative regulation of glucose import
0.54	GO:0030178	negative regulation of Wnt signaling pathway
0.49	GO:0042326	negative regulation of phosphorylation
0.39	GO:0045719	negative regulation of glycogen biosynthetic process
0.37	GO:0032869	cellular response to insulin stimulus
0.36	GO:0042327	positive regulation of phosphorylation

0.80	GO:0005158	insulin receptor binding
0.78	GO:0005070	SH3/SH2 adaptor activity
0.36	GO:0042802	identical protein binding
0.34	GO:0001784	phosphotyrosine residue binding

0.43	GO:0043234	protein complex
0.34	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane

sp|P0CE46|ZNT8_RAT
Zinc transporter 8
Search

SLC30A8

0.87	Solute carrier family 30 (zinc transporter), member 8

0.76	GO:0006882	cellular zinc ion homeostasis
0.74	GO:0071577	zinc II ion transmembrane transport
0.68	GO:0030073	insulin secretion
0.68	GO:0051238	sequestering of metal ion
0.66	GO:0061088	regulation of sequestering of zinc ion
0.66	GO:0009749	response to glucose
0.57	GO:0010043	response to zinc ion
0.55	GO:0032846	positive regulation of homeostatic process
0.49	GO:0048522	positive regulation of cellular process
0.46	GO:0003323	type B pancreatic cell development

0.75	GO:0005385	zinc ion transmembrane transporter activity
0.56	GO:0042803	protein homodimerization activity

0.64	GO:0031410	cytoplasmic vesicle
0.60	GO:0012505	endomembrane system
0.48	GO:0005886	plasma membrane
0.42	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|P0CF24|FOXP2_RAT
Forkhead box protein P2
Search

FOXP2

0.94	Forkhead box transcription factor

0.62	GO:0021758	putamen development
0.62	GO:0021757	caudate nucleus development
0.56	GO:0098596	imitative learning
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0098598	learned vocalization behavior or vocal learning
0.56	GO:0031223	auditory behavior
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.55	GO:0006351	transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0042803	protein homodimerization activity
0.50	GO:0044212	transcription regulatory region DNA binding
0.48	GO:0046982	protein heterodimerization activity
0.48	GO:0003690	double-stranded DNA binding
0.40	GO:0050681	androgen receptor binding
0.37	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.37	GO:0044297	cell body
0.30	GO:0031224	intrinsic component of membrane

sp|P0CG51|UBB_RAT
Polyubiquitin-B
Search

0.49	Polyubiquitin-B Ubiquitin

0.46	GO:0019082	viral protein processing
0.41	GO:0006508	proteolysis
0.30	GO:0140013	meiotic nuclear division
0.30	GO:1901796	regulation of signal transduction by p53 class mediator
0.30	GO:0042176	regulation of protein catabolic process
0.30	GO:0048468	cell development
0.30	GO:0051247	positive regulation of protein metabolic process
0.30	GO:0010942	positive regulation of cell death
0.30	GO:0051881	regulation of mitochondrial membrane potential
0.30	GO:0060322	head development

0.44

GO:0004252

serine-type endopeptidase activity

0.60	GO:0005840	ribosome
0.30	GO:0005615	extracellular space
0.30	GO:0005634	nucleus
0.30	GO:0043230	extracellular organelle
0.30	GO:0043209	myelin sheath
0.30	GO:0097458	neuron part
0.30	GO:0031982	vesicle
0.30	GO:0042995	cell projection
0.30	GO:0044297	cell body
0.30	GO:0005739	mitochondrion

0.44

GO:0004252

sp|P0CH38|FBSP1_RAT
F-box/SPRY domain-containing protein 1 (Fragment)
Search

FBXO45

0.70	F-box/SPRY domain-containing protein 1

0.75	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.73	GO:0007274	neuromuscular synaptic transmission
0.73	GO:0016567	protein ubiquitination
0.70	GO:0007399	nervous system development
0.68	GO:0045732	positive regulation of protein catabolic process
0.58	GO:0010629	negative regulation of gene expression
0.56	GO:0050808	synapse organization
0.56	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.55	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.55	GO:0060322	head development

0.44	GO:0005515	protein binding
0.40	GO:0004842	ubiquitin-protein transferase activity

0.74	GO:0019005	SCF ubiquitin ligase complex
0.72	GO:0045495	pole plasm
0.71	GO:0031594	neuromuscular junction
0.69	GO:0030054	cell junction
0.65	GO:0005938	cell cortex
0.58	GO:0014069	postsynaptic density
0.55	GO:0042734	presynaptic membrane
0.54	GO:0005634	nucleus
0.52	GO:0045211	postsynaptic membrane
0.43	GO:0043204	perikaryon

0.40

GO:0004842

sp|P0CI71|K0319_RAT
Dyslexia-associated protein KIAA0319 homolog
Search

KIAA0319L

0.95	Dyslexia-associated protein KIAA0319 homolog

0.53	GO:2000171	negative regulation of dendrite development
0.51	GO:0001764	neuron migration
0.35	GO:0061024	membrane organization

0.36

GO:0005515

protein binding

0.55	GO:0031410	cytoplasmic vesicle
0.45	GO:0012505	endomembrane system
0.41	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0005886	plasma membrane
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0098805	whole membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0044446	intracellular organelle part
0.37	GO:0012506	vesicle membrane
0.30	GO:0044425	membrane part

sp|P0DJJ3|SGIP1_RAT
SH3-containing GRB2-like protein 3-interacting protein 1
Search

SGIP1

0.85	SH3 domain GRB2 like endophilin interacting protein 1

0.70	GO:0072583	clathrin-dependent endocytosis
0.65	GO:0097320	plasma membrane tubulation
0.65	GO:0048260	positive regulation of receptor-mediated endocytosis
0.41	GO:0015031	protein transport
0.33	GO:2000507	positive regulation of energy homeostasis
0.33	GO:2000253	positive regulation of feeding behavior
0.33	GO:0002021	response to dietary excess

0.60	GO:0017124	SH3 domain binding
0.58	GO:0005543	phospholipid binding
0.57	GO:0008017	microtubule binding

0.64	GO:0030122	AP-2 adaptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|P0DKR2|TCAIM_RAT
T-cell activation inhibitor, mitochondrial
Search

TCAIM

0.95	T-cell activation inhibitor

0.60	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|P0DL28|FBXW8_RAT
F-box/WD repeat-containing protein 8
Search

FBXW8

0.97	F-box and WD repeat domain containing 8

0.86	GO:0050775	positive regulation of dendrite morphogenesis
0.84	GO:0060712	spongiotrophoblast layer development
0.84	GO:0060716	labyrinthine layer blood vessel development
0.82	GO:0007030	Golgi organization
0.79	GO:0008283	cell proliferation
0.72	GO:0016567	protein ubiquitination
0.41	GO:0043687	post-translational protein modification
0.40	GO:0006511	ubiquitin-dependent protein catabolic process

0.73	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0005515	protein binding

0.86	GO:1990393	3M complex
0.86	GO:0031467	Cul7-RING ubiquitin ligase complex
0.82	GO:0019005	SCF ubiquitin ligase complex
0.79	GO:0048471	perinuclear region of cytoplasm
0.71	GO:0005794	Golgi apparatus
0.68	GO:0005829	cytosol

0.73

GO:0004842

sp|P0DMW0|HS71A_RAT
Heat shock 70 kDa protein 1A
Search

0.53	Inducible heat shock protein 70

0.52	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0010638	positive regulation of organelle organization
0.51	GO:0042026	protein refolding
0.50	GO:0010821	regulation of mitochondrion organization
0.50	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.50	GO:1903533	regulation of protein targeting
0.50	GO:0090316	positive regulation of intracellular protein transport
0.48	GO:0010968	regulation of microtubule nucleation
0.47	GO:1901673	regulation of mitotic spindle assembly
0.44	GO:0032273	positive regulation of protein polymerization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0031072	heat shock protein binding
0.47	GO:0051082	unfolded protein binding
0.41	GO:0055131	C3HC4-type RING finger domain binding
0.41	GO:0031249	denatured protein binding
0.41	GO:0001106	RNA polymerase II transcription corepressor activity

0.53	GO:0002199	zona pellucida receptor complex
0.49	GO:0044297	cell body
0.49	GO:0008180	COP9 signalosome
0.46	GO:0005829	cytosol
0.44	GO:0005813	centrosome
0.41	GO:0072562	blood microparticle
0.40	GO:0016235	aggresome
0.39	GO:0005814	centriole
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0070062	extracellular exosome

0.34	EC:6.1.1.9	GO:0004832
0.34	KEGG:R03665	GO:0004832

sp|P0DMW1|HS71B_RAT
Heat shock 70 kDa protein 1B
Search

0.53	Inducible heat shock protein 70

0.52	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0010638	positive regulation of organelle organization
0.51	GO:0042026	protein refolding
0.50	GO:0010821	regulation of mitochondrion organization
0.50	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.50	GO:1903533	regulation of protein targeting
0.50	GO:0090316	positive regulation of intracellular protein transport
0.48	GO:0010968	regulation of microtubule nucleation
0.47	GO:1901673	regulation of mitotic spindle assembly
0.44	GO:0032273	positive regulation of protein polymerization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0031072	heat shock protein binding
0.47	GO:0051082	unfolded protein binding
0.41	GO:0055131	C3HC4-type RING finger domain binding
0.41	GO:0031249	denatured protein binding
0.41	GO:0001106	RNA polymerase II transcription corepressor activity

0.53	GO:0002199	zona pellucida receptor complex
0.49	GO:0044297	cell body
0.49	GO:0008180	COP9 signalosome
0.46	GO:0005829	cytosol
0.44	GO:0005813	centrosome
0.41	GO:0072562	blood microparticle
0.40	GO:0016235	aggresome
0.39	GO:0005814	centriole
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0070062	extracellular exosome

0.34	EC:6.1.1.9	GO:0004832
0.34	KEGG:R03665	GO:0004832

sp|P0DN35|NDUB1_RAT
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
Search

NDUFB1

0.97	Mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

0.57	GO:0032981	mitochondrial respiratory chain complex I assembly
0.53	GO:0055114	oxidation-reduction process
0.35	GO:0006119	oxidative phosphorylation

0.69	GO:0003954	NADH dehydrogenase activity
0.36	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

0.61	GO:0005739	mitochondrion
0.55	GO:0045271	respiratory chain complex I
0.50	GO:1990204	oxidoreductase complex
0.46	GO:0016607	nuclear speck
0.46	GO:0019866	organelle inner membrane
0.41	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.69

EC:1.6.99.3

GO:0003954

sp|P0DO93|ENOL_RAT
Putative protein T-ENOL
Search

sp|P10037|PIT1_RAT
Pituitary-specific positive transcription factor 1
Search

POU1F1

0.60	Pituitary-specific positive transcription factor 1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0010468	regulation of gene expression
0.54	GO:0060133	somatotropin secreting cell development
0.54	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.54	GO:0001708	cell fate specification
0.52	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.51	GO:0040018	positive regulation of multicellular organism growth
0.51	GO:0051254	positive regulation of RNA metabolic process

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001105	RNA polymerase II transcription coactivator activity
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.48	GO:0003682	chromatin binding
0.41	GO:0003714	transcription corepressor activity
0.41	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|P10065|CRGA_RAT
Gamma-crystallin A
Search

0.96	Gamma-crystallin A

0.75	GO:0002088	lens development in camera-type eye
0.63	GO:0007601	visual perception
0.60	GO:0030855	epithelial cell differentiation
0.55	GO:0048593	camera-type eye morphogenesis
0.53	GO:0000904	cell morphogenesis involved in differentiation
0.49	GO:0034614	cellular response to reactive oxygen species
0.41	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0005515	protein binding
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P10066|CRGB_RAT
Gamma-crystallin B
Search

0.97	Gamma-crystallin B

0.75	GO:0002088	lens development in camera-type eye
0.62	GO:0007601	visual perception
0.61	GO:0030855	epithelial cell differentiation
0.59	GO:0048593	camera-type eye morphogenesis
0.56	GO:0000904	cell morphogenesis involved in differentiation
0.47	GO:0034614	cellular response to reactive oxygen species
0.38	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.77	GO:0005212	structural constituent of eye lens
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding

0.55	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.35

GO:0004450

sp|P10067|CRGD_RAT
Gamma-crystallin D
Search

0.96	Gamma-crystallin D

0.77	GO:0002088	lens development in camera-type eye
0.62	GO:0007601	visual perception
0.62	GO:0030855	epithelial cell differentiation
0.57	GO:0048593	camera-type eye morphogenesis
0.54	GO:0000904	cell morphogenesis involved in differentiation
0.51	GO:0034614	cellular response to reactive oxygen species
0.42	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0005515	protein binding
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P10068|CRGF_RAT
Gamma-crystallin F
Search

0.96	Gamma-crystallin F

0.76	GO:0002088	lens development in camera-type eye
0.62	GO:0007601	visual perception
0.61	GO:0030855	epithelial cell differentiation
0.56	GO:0048593	camera-type eye morphogenesis
0.54	GO:0000904	cell morphogenesis involved in differentiation
0.50	GO:0034614	cellular response to reactive oxygen species
0.42	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0005515	protein binding
0.35	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.54	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P10093|CALCB_RAT
Calcitonin gene-related peptide 2
Search

0.96	Calcitonin receptor-stimulating peptide 1

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0055074	calcium ion homeostasis
0.42	GO:0045779	negative regulation of bone resorption
0.41	GO:0001984	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
0.41	GO:0019233	sensory perception of pain
0.41	GO:0007190	activation of adenylate cyclase activity
0.40	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.40	GO:0031645	negative regulation of neurological system process
0.40	GO:0050961	detection of temperature stimulus involved in sensory perception
0.40	GO:0072503	cellular divalent inorganic cation homeostasis

0.79	GO:0005179	hormone activity
0.41	GO:0031716	calcitonin receptor binding
0.36	GO:0042802	identical protein binding
0.35	GO:0032403	protein complex binding

0.66	GO:0005576	extracellular region
0.40	GO:0043025	neuronal cell body
0.39	GO:0043195	terminal bouton
0.34	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P10111|PPIA_RAT
Peptidyl-prolyl cis-trans isomerase A
Search

PPIA

0.48	Peptidyl-prolyl cis-trans isomerase A

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.67	GO:0006457	protein folding
0.49	GO:0045069	regulation of viral genome replication
0.41	GO:0034389	lipid particle organization
0.41	GO:1903902	positive regulation of viral life cycle
0.40	GO:0050714	positive regulation of protein secretion
0.37	GO:0030182	neuron differentiation
0.35	GO:0019061	uncoating of virus
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0043312	neutrophil degranulation

0.71	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0016018	cyclosporin A binding
0.35	GO:0046790	virion binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding

0.43	GO:0005829	cytosol
0.43	GO:0005576	extracellular region
0.41	GO:0005634	nucleus
0.37	GO:0043209	myelin sheath
0.36	GO:0005925	focal adhesion
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0030496	midbody
0.30	GO:0016020	membrane

0.71

EC:5.2.1.8

GO:0003755

sp|P10118|HSP1_RAT
Sperm protamine P1
Search

PRM1

0.96	Protamine 1

0.79	GO:0007283	spermatogenesis
0.75	GO:0030261	chromosome condensation
0.71	GO:0030154	cell differentiation
0.68	GO:0007275	multicellular organism development
0.41	GO:0022412	cellular process involved in reproduction in multicellular organism
0.40	GO:0003006	developmental process involved in reproduction
0.40	GO:0006997	nucleus organization

0.54

GO:0003677

DNA binding

0.73	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

sp|P10158|FOSL1_RAT
Fos-related antigen 1
Search

FOSL1

0.93	FBJ murine osteosarcoma viral oncogene homolog B

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.65	GO:0007296	vitellogenesis
0.64	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.63	GO:0060674	placenta blood vessel development
0.61	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.59	GO:0001701	in utero embryonic development
0.53	GO:0031668	cellular response to extracellular stimulus
0.47	GO:0051412	response to corticosterone
0.47	GO:0071277	cellular response to calcium ion
0.46	GO:0032570	response to progesterone

0.62	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding
0.32	GO:0005509	calcium ion binding

0.60	GO:0005634	nucleus
0.54	GO:0031974	membrane-enclosed lumen
0.48	GO:0044446	intracellular organelle part
0.44	GO:0042734	presynaptic membrane
0.42	GO:0043005	neuron projection
0.40	GO:0005829	cytosol
0.35	GO:0005667	transcription factor complex
0.32	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P10164|PRP2_RAT
Acidic proline-rich protein PRP25 (Fragment)
Search

0.59	Basic salivary proline-rich protein 4

0.44	GO:0006342	chromatin silencing
0.42	GO:0006888	ER to Golgi vesicle-mediated transport
0.42	GO:0006338	chromatin remodeling
0.42	GO:1904263	positive regulation of TORC1 signaling
0.41	GO:0048194	Golgi vesicle budding
0.39	GO:0015031	protein transport
0.39	GO:0050829	defense response to Gram-negative bacterium
0.37	GO:0030163	protein catabolic process
0.37	GO:0007269	neurotransmitter secretion
0.36	GO:0051301	cell division

0.42	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.41	GO:0003682	chromatin binding
0.39	GO:0008270	zinc ion binding
0.37	GO:0005544	calcium-dependent phospholipid binding
0.37	GO:0005198	structural molecule activity
0.37	GO:0004222	metalloendopeptidase activity
0.37	GO:0140110	transcription regulator activity
0.37	GO:0003723	RNA binding
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding

0.50	GO:0005576	extracellular region
0.43	GO:0030133	transport vesicle
0.43	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.42	GO:0030120	vesicle coat
0.42	GO:0030660	Golgi-associated vesicle membrane
0.39	GO:0000139	Golgi membrane
0.38	GO:0005634	nucleus
0.36	GO:0099503	secretory vesicle
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0098793	presynapse

0.37

GO:0004222

sp|P10165|PRPG2_RAT
Proline-rich proteoglycan 2
Search

0.64	Basic salivary proline-rich protein 1

0.42	GO:0018298	protein-chromophore linkage
0.41	GO:1904263	positive regulation of TORC1 signaling
0.41	GO:0090114	COPII-coated vesicle budding
0.41	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0050829	defense response to Gram-negative bacterium
0.39	GO:0099643	signal release from synapse
0.39	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.38	GO:0007602	phototransduction
0.38	GO:0007601	visual perception
0.38	GO:0006836	neurotransmitter transport

0.43	GO:0009881	photoreceptor activity
0.41	GO:0004930	G-protein coupled receptor activity
0.38	GO:0016918	retinal binding
0.37	GO:0004222	metalloendopeptidase activity
0.37	GO:0005198	structural molecule activity
0.37	GO:0016887	ATPase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0005515	protein binding
0.36	GO:0008270	zinc ion binding
0.36	GO:0008144	drug binding

0.51	GO:0005576	extracellular region
0.43	GO:0030133	transport vesicle
0.40	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.40	GO:0030120	vesicle coat
0.40	GO:0030660	Golgi-associated vesicle membrane
0.39	GO:0000139	Golgi membrane
0.39	GO:0099503	secretory vesicle
0.39	GO:0098793	presynapse
0.38	GO:0005581	collagen trimer
0.35	GO:0005886	plasma membrane

0.37

GO:0004222

sp|P10247|HG2A_RAT
H-2 class II histocompatibility antigen gamma chain
Search

CD74

0.94	Major histocompatibility complex class II invariant chain

0.73	GO:0070206	protein trimerization
0.69	GO:0019882	antigen processing and presentation
0.66	GO:0006955	immune response
0.64	GO:0035691	macrophage migration inhibitory factor signaling pathway
0.62	GO:0006886	intracellular protein transport
0.62	GO:0002905	regulation of mature B cell apoptotic process
0.62	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.62	GO:0002606	positive regulation of dendritic cell antigen processing and presentation
0.62	GO:0060907	positive regulation of macrophage cytokine production
0.61	GO:0045059	positive thymic T cell selection

0.81	GO:0042289	MHC class II protein binding
0.62	GO:0035718	macrophage migration inhibitory factor binding
0.61	GO:0023026	MHC class II protein complex binding
0.61	GO:0050998	nitric-oxide synthase binding
0.58	GO:0001540	amyloid-beta binding
0.58	GO:0044183	protein binding involved in protein folding
0.56	GO:0004896	cytokine receptor activity
0.54	GO:0042609	CD4 receptor binding
0.51	GO:0005509	calcium ion binding
0.42	GO:0043237	laminin-1 binding

0.63	GO:0035693	NOS2-CD74 complex
0.63	GO:0035692	macrophage migration inhibitory factor receptor complex
0.59	GO:0005771	multivesicular body
0.56	GO:0009897	external side of plasma membrane
0.55	GO:0005764	lysosome
0.53	GO:0042613	MHC class II protein complex
0.51	GO:0005794	Golgi apparatus
0.51	GO:0005783	endoplasmic reticulum
0.48	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0005615	extracellular space

0.37

EC:2.7.10.1

GO:0004714

sp|P10252|CD48_RAT
CD48 antigen
Search

sp|P10354|CMGA_RAT
Chromogranin-A
Search

CHGA

0.97	Chromogranin A

0.66	GO:2000707	positive regulation of dense core granule biogenesis
0.66	GO:0032762	mast cell cytokine production
0.65	GO:0002551	mast cell chemotaxis
0.65	GO:0033604	negative regulation of catecholamine secretion
0.63	GO:0002279	mast cell activation involved in immune response
0.63	GO:0002448	mast cell mediated immunity
0.62	GO:0043299	leukocyte degranulation
0.61	GO:0032418	lysosome localization
0.60	GO:0050830	defense response to Gram-positive bacterium
0.60	GO:0050829	defense response to Gram-negative bacterium

0.37	GO:0005515	protein binding
0.35	GO:0005223	intracellular cGMP activated cation channel activity
0.35	GO:0005222	intracellular cAMP activated cation channel activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0030553	cGMP binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0016787	hydrolase activity

0.77	GO:0030141	secretory granule
0.63	GO:0042629	mast cell granule
0.56	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0030658	transport vesicle membrane
0.41	GO:0005615	extracellular space
0.35	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.34	GO:0043195	terminal bouton
0.34	GO:0001750	photoreceptor outer segment
0.33	GO:0005634	nucleus
0.33	GO:0044427	chromosomal part

0.32

GO:0016787

sp|P10361|P53_RAT
Cellular tumor antigen p53
Search

TP53

0.85	Cellular tumor antigen p53

0.78	GO:0006915	apoptotic process
0.74	GO:0051262	protein tetramerization
0.67	GO:0007049	cell cycle
0.61	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.61	GO:0000733	DNA strand renaturation
0.59	GO:0030308	negative regulation of cell growth
0.58	GO:0007569	cell aging
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0072717	cellular response to actinomycin D
0.57	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001084	transcription factor activity, TFIID-class binding
0.55	GO:0001094	TFIID-class transcription factor binding
0.55	GO:0002039	p53 binding
0.55	GO:0035035	histone acetyltransferase binding
0.54	GO:0051721	protein phosphatase 2A binding
0.54	GO:0097718	disordered domain specific binding
0.54	GO:1990837	sequence-specific double-stranded DNA binding
0.54	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.51	GO:0005667	transcription factor complex
0.49	GO:0000785	chromatin
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0005737	cytoplasm
0.45	GO:0012505	endomembrane system
0.42	GO:0005657	replication fork
0.37	GO:0035861	site of double-strand break
0.33	GO:0005886	plasma membrane

sp|P10362|SCG2_RAT
Secretogranin-2
Search

SCG2

0.97	Secretogranin II

0.62	GO:0048245	eosinophil chemotaxis
0.62	GO:0050930	induction of positive chemotaxis
0.61	GO:2000352	negative regulation of endothelial cell apoptotic process
0.60	GO:0050918	positive chemotaxis
0.59	GO:0001938	positive regulation of endothelial cell proliferation
0.59	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.57	GO:0001525	angiogenesis
0.56	GO:0000165	MAPK cascade
0.54	GO:0010469	regulation of receptor activity
0.37	GO:0001937	negative regulation of endothelial cell proliferation

0.61	GO:0042056	chemoattractant activity
0.56	GO:0005125	cytokine activity

0.81	GO:0030141	secretory granule
0.53	GO:0005615	extracellular space
0.52	GO:0097458	neuron part
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0030117	membrane coat
0.34	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

sp|P10499|KCNA1_RAT
Potassium voltage-gated channel subfamily A member 1
Search

KCNA1

0.91	Potassium channel

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.57	GO:0071286	cellular response to magnesium ion
0.57	GO:0010960	magnesium ion homeostasis
0.57	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.57	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.56	GO:0019228	neuronal action potential
0.55	GO:0001964	startle response
0.55	GO:0007405	neuroblast proliferation

0.77	GO:0005249	voltage-gated potassium channel activity
0.56	GO:0097718	disordered domain specific binding
0.34	GO:0019894	kinesin binding

0.77	GO:0008076	voltage-gated potassium channel complex
0.62	GO:0044224	juxtaparanode region of axon
0.58	GO:0043679	axon terminus
0.57	GO:0033270	paranode region of axon
0.56	GO:0043025	neuronal cell body
0.56	GO:0030425	dendrite
0.50	GO:0030054	cell junction
0.50	GO:0009986	cell surface
0.45	GO:0044298	cell body membrane
0.40	GO:0042734	presynaptic membrane

sp|P10536|RAB1B_RAT
Ras-related protein Rab-1B
Search

RAB1B

0.85	Ras-related protein ORAB-1

0.56	GO:1903020	positive regulation of glycoprotein metabolic process
0.54	GO:0006888	ER to Golgi vesicle-mediated transport
0.50	GO:2000785	regulation of autophagosome assembly
0.48	GO:0019068	virion assembly
0.48	GO:0072606	interleukin-8 secretion
0.48	GO:0030252	growth hormone secretion
0.47	GO:0032402	melanosome transport
0.46	GO:0034446	substrate adhesion-dependent cell spreading
0.46	GO:0006914	autophagy
0.46	GO:0047496	vesicle transport along microtubule

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0045296	cadherin binding
0.35	GO:0003777	microtubule motor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.51	GO:0005794	Golgi apparatus
0.51	GO:0034045	phagophore assembly site membrane
0.49	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.47	GO:0042470	melanosome
0.47	GO:0098588	bounding membrane of organelle
0.46	GO:0031984	organelle subcompartment
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.45	GO:0044432	endoplasmic reticulum part
0.41	GO:0005739	mitochondrion
0.38	GO:0005769	early endosome

0.34

EC:2.7.10

GO:0004713

sp|P10608|ADRB2_RAT
Beta-2 adrenergic receptor
Search

ADRB2

0.87	Beta-2 adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.85	GO:0006940	regulation of smooth muscle contraction
0.84	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.82	GO:0097746	regulation of blood vessel diameter
0.54	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin
0.53	GO:0007190	activation of adenylate cyclase activity
0.52	GO:1904502	regulation of lipophagy
0.52	GO:1901098	positive regulation of autophagosome maturation
0.51	GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine
0.50	GO:0061885	positive regulation of mini excitatory postsynaptic potential

0.86	GO:0004941	beta2-adrenergic receptor activity
0.54	GO:0051380	norepinephrine binding
0.49	GO:0008179	adenylate cyclase binding
0.49	GO:0015459	potassium channel regulator activity
0.48	GO:0001540	amyloid-beta binding
0.47	GO:0042803	protein homodimerization activity
0.46	GO:0051379	epinephrine binding
0.44	GO:0032403	protein complex binding
0.37	GO:0031713	B2 bradykinin receptor binding
0.36	GO:0090722	receptor-receptor interaction

0.49	GO:0043235	receptor complex
0.46	GO:0016324	apical plasma membrane
0.46	GO:0005769	early endosome
0.43	GO:0005887	integral component of plasma membrane
0.40	GO:0005634	nucleus
0.36	GO:0032809	neuronal cell body membrane
0.36	GO:0098805	whole membrane
0.36	GO:0043197	dendritic spine
0.36	GO:0042383	sarcolemma
0.35	GO:0030424	axon

sp|P10610|CP2G1_RAT
Cytochrome P450 2G1
Search

0.96	Felis catus cytochrome P450, family 2, subfamily A, polypeptide 13

0.62	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0090420	naphthalene-containing compound metabolic process
0.48	GO:0043651	linoleic acid metabolic process
0.41	GO:0009636	response to toxic substance
0.39	GO:0017144	drug metabolic process

0.74	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.64	GO:0008392	arachidonic acid epoxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.57	GO:0008395	steroid hydroxylase activity
0.49	GO:0071614	linoleic acid epoxygenase activity
0.45	GO:0019825	oxygen binding
0.43	GO:0005515	protein binding

0.30

GO:0031224

intrinsic component of membrane

0.74

GO:0016712

sp|P10631|PYY_RAT
Peptide YY
Search

PYY

0.91	Pro-neuropeptide Y

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0007218	neuropeptide signaling pathway
0.56	GO:0007631	feeding behavior
0.56	GO:0032098	regulation of appetite
0.53	GO:0007586	digestion
0.50	GO:0007267	cell-cell signaling
0.38	GO:0032096	negative regulation of response to food
0.38	GO:0008217	regulation of blood pressure
0.36	GO:0008283	cell proliferation
0.36	GO:0021954	central nervous system neuron development

0.79	GO:0005179	hormone activity
0.53	GO:0001664	G-protein coupled receptor binding
0.35	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.35	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|P10633|CP2D1_RAT
Cytochrome P450 2D1
Search

0.97	Cytochrome P450, family 2, subfamily d, polypeptide 5

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0019369	arachidonic acid metabolic process
0.39	GO:0007565	female pregnancy
0.38	GO:0090349	negative regulation of cellular organohalogen metabolic process
0.38	GO:0090348	regulation of cellular organofluorine metabolic process
0.37	GO:0042738	exogenous drug catabolic process
0.37	GO:0009822	alkaloid catabolic process
0.37	GO:0033076	isoquinoline alkaloid metabolic process
0.37	GO:0006587	serotonin biosynthetic process from tryptophan
0.37	GO:0009804	coumarin metabolic process

0.80	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.50	GO:0008395	steroid hydroxylase activity
0.37	GO:0008391	arachidonic acid monooxygenase activity
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0016712

sp|P10634|CP2DQ_RAT
Cytochrome P450 2D26
Search

0.95	Cytochrome P450, family 2, subfamily d, polypeptide 5

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0019369	arachidonic acid metabolic process
0.39	GO:0007565	female pregnancy
0.38	GO:0090349	negative regulation of cellular organohalogen metabolic process
0.38	GO:0090348	regulation of cellular organofluorine metabolic process
0.37	GO:0009822	alkaloid catabolic process
0.37	GO:0033076	isoquinoline alkaloid metabolic process
0.37	GO:0006587	serotonin biosynthetic process from tryptophan
0.37	GO:0008202	steroid metabolic process
0.37	GO:0009804	coumarin metabolic process

0.80	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.50	GO:0008395	steroid hydroxylase activity
0.37	GO:0008391	arachidonic acid monooxygenase activity
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0016712

sp|P10683|GALA_RAT
Galanin peptides
Search

GAL

0.97	Galanin and GMAP prepropeptide

0.75	GO:0010469	regulation of receptor activity
0.63	GO:1902890	regulation of root hair elongation
0.62	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
0.62	GO:1905422	negative regulation of plant organ morphogenesis
0.62	GO:1903889	negative regulation of plant epidermal cell differentiation
0.61	GO:0051795	positive regulation of timing of catagen
0.61	GO:0051464	positive regulation of cortisol secretion
0.60	GO:1903430	negative regulation of cell maturation
0.60	GO:0010737	protein kinase A signaling
0.58	GO:0007218	neuropeptide signaling pathway

0.79	GO:0005179	hormone activity
0.65	GO:0031763	galanin receptor binding
0.62	GO:0004966	galanin receptor activity

0.66	GO:0005576	extracellular region
0.55	GO:0043025	neuronal cell body
0.49	GO:0030141	secretory granule
0.40	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|P10686|PLCG1_RAT
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Search

PLCG1

0.52	Phosphoinositide phospholipase C

0.76	GO:0009395	phospholipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.56	GO:1901342	regulation of vasculature development
0.55	GO:0071364	cellular response to epidermal growth factor stimulus
0.55	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.55	GO:0030334	regulation of cell migration
0.54	GO:0050852	T cell receptor signaling pathway
0.54	GO:0007173	epidermal growth factor receptor signaling pathway
0.51	GO:2000147	positive regulation of cell motility
0.50	GO:0016477	cell migration

0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.63	GO:0004871	signal transducer activity
0.62	GO:0005509	calcium ion binding
0.56	GO:0005168	neurotrophin TRKA receptor binding
0.55	GO:0035254	glutamate receptor binding
0.54	GO:0030971	receptor tyrosine kinase binding

0.52	GO:0001726	ruffle
0.52	GO:0030027	lamellipodium
0.52	GO:0008180	COP9 signalosome
0.50	GO:0005911	cell-cell junction
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

sp|P10687|PLCB1_RAT
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
Search

PLCB1

0.52	Phosphoinositide phospholipase C

0.79	GO:0007420	brain development
0.72	GO:0051726	regulation of cell cycle
0.72	GO:0016042	lipid catabolic process
0.62	GO:0035556	intracellular signal transduction
0.57	GO:2000560	positive regulation of CD24 biosynthetic process
0.57	GO:2000438	negative regulation of monocyte extravasation
0.56	GO:0035723	interleukin-15-mediated signaling pathway
0.56	GO:0035722	interleukin-12-mediated signaling pathway
0.55	GO:2000344	positive regulation of acrosome reaction
0.55	GO:0048009	insulin-like growth factor receptor signaling pathway

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.69	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.54	GO:0005521	lamin binding
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.51	GO:0005516	calmodulin binding
0.49	GO:0005096	GTPase activator activity
0.47	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.51	GO:0043209	myelin sheath
0.48	GO:0005737	cytoplasm
0.47	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

sp|P10688|PLCD1_RAT
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
Search

PLCD1

0.52	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

0.85	GO:0060716	labyrinthine layer blood vessel development
0.79	GO:0001525	angiogenesis
0.74	GO:0042127	regulation of cell proliferation
0.70	GO:0016042	lipid catabolic process
0.64	GO:0034696	response to prostaglandin F
0.63	GO:0010701	positive regulation of norepinephrine secretion
0.63	GO:0035556	intracellular signal transduction
0.61	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.60	GO:0010044	response to aluminum ion
0.59	GO:0055093	response to hyperoxia

0.85	GO:0032794	GTPase activating protein binding
0.85	GO:0070300	phosphatidic acid binding
0.85	GO:0001786	phosphatidylserine binding
0.83	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.68	GO:0005509	calcium ion binding
0.62	GO:0004871	signal transducer activity
0.58	GO:0070679	inositol 1,4,5 trisphosphate binding
0.55	GO:0005544	calcium-dependent phospholipid binding

0.67	GO:0005829	cytosol
0.65	GO:0070062	extracellular exosome
0.55	GO:0045121	membrane raft
0.46	GO:0031966	mitochondrial membrane
0.46	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

sp|P10715|CYC2_RAT
Cytochrome c, testis-specific
Search

CYCS

0.63	Cytochrome c, somatic A

0.61	GO:0022900	electron transport chain
0.53	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0006119	oxidative phosphorylation
0.44	GO:0009060	aerobic respiration
0.38	GO:0006915	apoptotic process
0.38	GO:0042743	hydrogen peroxide metabolic process

0.63	GO:0020037	heme binding
0.62	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding

0.62	GO:0070469	respiratory chain
0.61	GO:0005739	mitochondrion
0.58	GO:0031970	organelle envelope lumen
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.39	GO:0043209	myelin sheath

sp|P10716|CLC4F_RAT
C-type lectin domain family 4 member F
Search

CLEC4F

0.81	C-type lectin domain family 4 member F

0.52	GO:0051132	NK T cell activation
0.46	GO:0006897	endocytosis
0.39	GO:0002764	immune response-regulating signaling pathway
0.38	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.38	GO:0055088	lipid homeostasis
0.38	GO:0060355	positive regulation of cell adhesion molecule production
0.38	GO:0071360	cellular response to exogenous dsRNA
0.38	GO:0031647	regulation of protein stability
0.37	GO:0006955	immune response
0.37	GO:0009100	glycoprotein metabolic process

0.69	GO:0030246	carbohydrate binding
0.51	GO:0051861	glycolipid binding
0.41	GO:0004872	receptor activity
0.38	GO:0030169	low-density lipoprotein particle binding
0.38	GO:0036094	small molecule binding
0.35	GO:0004871	signal transducer activity

0.46	GO:0005581	collagen trimer
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P10719|ATPB_RAT
ATP synthase subunit beta, mitochondrial
Search

ATP5B

0.43	Mitochondrial ATP synthase subunit beta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.54	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration
0.53	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.51	GO:0051453	regulation of intracellular pH
0.51	GO:0001525	angiogenesis
0.42	GO:0006629	lipid metabolic process
0.37	GO:0001649	osteoblast differentiation
0.35	GO:0040039	inductive cell migration

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0043532	angiostatin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0042288	MHC class I protein binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.35	GO:0030228	lipoprotein particle receptor activity
0.34	GO:0019904	protein domain specific binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0042645	mitochondrial nucleoid
0.50	GO:0043209	myelin sheath
0.49	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.48	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0098857	membrane microdomain

sp|P10758|LITH_RAT
Lithostathine
Search

0.95	Regenerating islet-derived protein 3-gamma

0.61	GO:1904697	regulation of acinar cell proliferation
0.61	GO:1990867	response to gastrin
0.61	GO:1990864	response to growth hormone-releasing hormone
0.61	GO:1903492	response to acetylsalicylate
0.60	GO:0010469	regulation of receptor activity
0.60	GO:1990785	response to water-immersion restraint stress
0.59	GO:1904692	positive regulation of type B pancreatic cell proliferation
0.58	GO:0007399	nervous system development
0.57	GO:1990868	response to chemokine
0.57	GO:1990798	pancreas regeneration

0.62	GO:0008083	growth factor activity
0.61	GO:2001065	mannan binding
0.55	GO:0008201	heparin binding
0.54	GO:0019903	protein phosphatase binding
0.50	GO:0042803	protein homodimerization activity
0.41	GO:0070492	oligosaccharide binding
0.39	GO:0042834	peptidoglycan binding
0.37	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.36	GO:0005509	calcium ion binding

0.57	GO:0042588	zymogen granule
0.56	GO:0032809	neuronal cell body membrane
0.56	GO:0032590	dendrite membrane
0.55	GO:0045178	basal part of cell
0.54	GO:0005615	extracellular space
0.54	GO:0030426	growth cone
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:1903561	extracellular vesicle
0.47	GO:0005829	cytosol
0.43	GO:0043234	protein complex

0.37	EC:2.3.3.10	GO:0004421
0.37	KEGG:R01978	GO:0004421

sp|P10759|AMPD1_RAT
AMP deaminase 1
Search

AMPD1

0.74	Adenosine monophosphate deaminase 1

0.79	GO:0032264	IMP salvage
0.41	GO:0097009	energy homeostasis
0.40	GO:0034101	erythrocyte homeostasis
0.38	GO:0046039	GTP metabolic process
0.38	GO:0046033	AMP metabolic process
0.37	GO:0046031	ADP metabolic process
0.37	GO:0010033	response to organic substance
0.36	GO:0046034	ATP metabolic process
0.33	GO:0007165	signal transduction

0.84	GO:0003876	AMP deaminase activity
0.50	GO:0046872	metal ion binding
0.39	GO:0032036	myosin heavy chain binding
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.84

EC:3.5.4.6

GO:0003876

sp|P10760|SAHH_RAT
Adenosylhomocysteinase
Search

AHCY

0.56	Adenosylhomocysteinase A

0.77	GO:0019510	S-adenosylhomocysteine catabolic process
0.72	GO:0006730	one-carbon metabolic process
0.48	GO:0033353	S-adenosylmethionine cycle
0.38	GO:0002439	chronic inflammatory response to antigenic stimulus
0.37	GO:0042745	circadian sleep/wake cycle
0.36	GO:0071268	homocysteine biosynthetic process
0.36	GO:0001666	response to hypoxia
0.36	GO:0007584	response to nutrient
0.34	GO:0048033	heme o metabolic process
0.33	GO:0006783	heme biosynthetic process

0.80	GO:0004013	adenosylhomocysteinase activity
0.65	GO:0051287	NAD binding
0.38	GO:0043621	protein self-association
0.36	GO:0098604	adenosylselenohomocysteinase activity
0.36	GO:0005507	copper ion binding
0.35	GO:0042802	identical protein binding
0.34	GO:0008495	protoheme IX farnesyltransferase activity
0.33	GO:0030554	adenyl nucleotide binding

0.47	GO:0005829	cytosol
0.41	GO:0042470	melanosome
0.36	GO:0070062	extracellular exosome
0.36	GO:0043005	neuron projection
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80

EC:3.3.1.1

GO:0004013

sp|P10817|CX6A2_RAT
Cytochrome c oxidase subunit 6A2, mitochondrial (Fragment)
Search

COX6A2

0.81	Cytochrome c oxidase subunit 6A, mitochondrial

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.43	GO:0050790	regulation of catalytic activity
0.41	GO:0006119	oxidative phosphorylation
0.41	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.44	GO:0030234	enzyme regulator activity

0.84	GO:0005751	mitochondrial respiratory chain complex IV
0.35	GO:0043209	myelin sheath
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

sp|P10818|CX6A1_RAT
Cytochrome c oxidase subunit 6A1, mitochondrial
Search

COX6A1

0.81	Cytochrome c oxidase subunit 6A, mitochondrial

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.43	GO:0050790	regulation of catalytic activity
0.42	GO:0006119	oxidative phosphorylation
0.42	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.44	GO:0030234	enzyme regulator activity

0.84	GO:0005751	mitochondrial respiratory chain complex IV
0.37	GO:0043209	myelin sheath
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016676

sp|P10824|GNAI1_RAT
Guanine nucleotide-binding protein G(i) subunit alpha-1
Search

GNAI1

0.79	Guanine nucleotide binding protein alpha inhibiting 1

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.57	GO:1904778	positive regulation of protein localization to cell cortex
0.54	GO:0060236	regulation of mitotic spindle organization
0.49	GO:0051301	cell division
0.44	GO:0007212	dopamine receptor signaling pathway
0.44	GO:0016239	positive regulation of macroautophagy
0.44	GO:1904321	response to forskolin
0.43	GO:0043949	regulation of cAMP-mediated signaling
0.42	GO:1901655	cellular response to ketone
0.42	GO:0046039	GTP metabolic process

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031821	G-protein coupled serotonin receptor binding
0.38	GO:0032794	GTPase activating protein binding
0.38	GO:0000287	magnesium ion binding

0.57	GO:0030496	midbody
0.54	GO:0005813	centrosome
0.53	GO:0099738	cell cortex region
0.51	GO:0005730	nucleolus
0.47	GO:1905360	GTPase complex
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0098797	plasma membrane protein complex
0.41	GO:0000139	Golgi membrane
0.41	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0045121	membrane raft

sp|P10860|DHE3_RAT
Glutamate dehydrogenase 1, mitochondrial
Search

GLUD1

0.45	Glutamate dehydrogenase

0.57	GO:0006520	cellular amino acid metabolic process
0.51	GO:0055114	oxidation-reduction process
0.47	GO:0032024	positive regulation of insulin secretion
0.43	GO:0072350	tricarboxylic acid metabolic process
0.42	GO:0043649	dicarboxylic acid catabolic process
0.40	GO:0032094	response to food
0.39	GO:0043650	dicarboxylic acid biosynthetic process
0.39	GO:1901565	organonitrogen compound catabolic process
0.38	GO:0021762	substantia nigra development
0.38	GO:0010044	response to aluminum ion

0.72	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.44	GO:0070728	leucine binding
0.40	GO:0043531	ADP binding
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.38	GO:0070403	NAD+ binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.46	GO:0005759	mitochondrial matrix
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane

0.72

EC:1.4.1

GO:0016639

sp|P10867|GGLO_RAT
L-gulonolactone oxidase
Search

GULO

0.77	L-gulono-gamma-lactone oxidase

0.56	GO:0019853	L-ascorbic acid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.35	GO:0006508	proteolysis

0.82	GO:0003885	D-arabinono-1,4-lactone oxidase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.58	GO:0050105	L-gulonolactone oxidase activity
0.36	GO:0004222	metalloendopeptidase activity

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.1.3.37	GO:0003885
0.82	KEGG:R02715	GO:0003885

sp|P10868|GAMT_RAT
Guanidinoacetate N-methyltransferase
Search

GAMT

0.97	Guanidinoacetate N-methyltransferase A

0.77	GO:0006601	creatine biosynthetic process
0.61	GO:0032259	methylation
0.53	GO:0040014	regulation of multicellular organism growth
0.51	GO:0007283	spermatogenesis
0.50	GO:0009887	animal organ morphogenesis
0.45	GO:0046498	S-adenosylhomocysteine metabolic process
0.45	GO:0046500	S-adenosylmethionine metabolic process
0.37	GO:1990402	embryonic liver development
0.35	GO:0006936	muscle contraction

0.84	GO:0030731	guanidinoacetate N-methyltransferase activity
0.35	GO:0042803	protein homodimerization activity

0.40	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.36	GO:0005902	microvillus
0.30	GO:0016020	membrane

0.84	EC:2.1.1.2	GO:0030731
0.84	KEGG:R01883	GO:0030731

sp|P10888|COX41_RAT
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Search

COX4I1

0.56	Mitochondrial cytochrome c oxidase subunit IV

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.41	GO:0001666	response to hypoxia
0.40	GO:0006119	oxidative phosphorylation
0.40	GO:0009060	aerobic respiration
0.39	GO:0007584	response to nutrient
0.34	GO:0006470	protein dephosphorylation
0.34	GO:0050829	defense response to Gram-negative bacterium
0.34	GO:0007017	microtubule-based process
0.33	GO:0007010	cytoskeleton organization

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.35	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0001530	lipopolysaccharide binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity

0.55	GO:0005751	mitochondrial respiratory chain complex IV
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P10937|PNMT_RAT
Phenylethanolamine N-methyltransferase
Search

PNMT

0.94	Phenylethanolamine N-methyltransferase

0.63	GO:0032259	methylation
0.45	GO:0042418	epinephrine biosynthetic process
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0035900	response to isolation stress
0.37	GO:0048513	animal organ development
0.37	GO:0035902	response to immobilization stress
0.37	GO:0045472	response to ether
0.37	GO:0042415	norepinephrine metabolic process
0.37	GO:0031099	regeneration
0.37	GO:0071549	cellular response to dexamethasone stimulus

0.63	GO:0008168	methyltransferase activity
0.32	GO:0005515	protein binding

0.44	GO:0005829	cytosol
0.37	GO:0043196	varicosity
0.36	GO:0043204	perikaryon
0.36	GO:0043195	terminal bouton
0.36	GO:0030425	dendrite
0.33	GO:0005634	nucleus

0.63

EC:2.1.1

GO:0008168

sp|P10959|EST1C_RAT
Carboxylesterase 1C
Search

0.57	Liver carboxylesterase

0.55	GO:0051791	medium-chain fatty acid metabolic process
0.55	GO:0034377	plasma lipoprotein particle assembly
0.53	GO:0006695	cholesterol biosynthetic process
0.51	GO:0019626	short-chain fatty acid catabolic process
0.50	GO:0030855	epithelial cell differentiation
0.50	GO:0046464	acylglycerol catabolic process
0.47	GO:0090122	cholesterol ester hydrolysis involved in cholesterol transport
0.46	GO:0090320	regulation of chylomicron remnant clearance
0.43	GO:0090207	regulation of triglyceride metabolic process
0.43	GO:0009636	response to toxic substance

0.69	GO:0052689	carboxylic ester hydrolase activity
0.49	GO:0016298	lipase activity
0.44	GO:0016290	palmitoyl-CoA hydrolase activity
0.41	GO:0019213	deacetylase activity

0.76	GO:0005788	endoplasmic reticulum lumen
0.51	GO:0005811	lipid droplet
0.48	GO:0005829	cytosol
0.41	GO:0005576	extracellular region

0.69	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.69	KEGG:R00630	GO:0052689

sp|P10960|SAP_RAT
Prosaposin
Search

PSAP

0.64	Prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)

0.79	GO:0006665	sphingolipid metabolic process
0.55	GO:1905572	ganglioside GM1 transport to membrane
0.53	GO:0060742	epithelial cell differentiation involved in prostate gland development
0.53	GO:0060736	prostate gland growth
0.52	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.52	GO:1901032	negative regulation of response to reactive oxygen species
0.52	GO:2001039	negative regulation of cellular response to drug
0.51	GO:1903205	regulation of hydrogen peroxide-induced cell death
0.51	GO:1903202	negative regulation of oxidative stress-induced cell death
0.49	GO:0019216	regulation of lipid metabolic process

0.55	GO:1905577	ganglioside GP1c binding
0.55	GO:1905574	ganglioside GM2 binding
0.55	GO:1905575	ganglioside GM3 binding
0.54	GO:1905573	ganglioside GM1 binding
0.54	GO:1905576	ganglioside GT1b binding
0.50	GO:0001664	G-protein coupled receptor binding
0.48	GO:0004565	beta-galactosidase activity
0.47	GO:0005543	phospholipid binding
0.47	GO:0042803	protein homodimerization activity
0.42	GO:0008047	enzyme activator activity

0.79	GO:0005764	lysosome
0.48	GO:0005615	extracellular space
0.47	GO:0031012	extracellular matrix
0.41	GO:0005739	mitochondrion
0.38	GO:1903561	extracellular vesicle

0.48

EC:3.2.1.23

GO:0004565

sp|P10980|ACM2_RAT
Muscarinic acetylcholine receptor M2
Search

CHRM2

0.81	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.76	GO:0008016	regulation of heart contraction
0.54	GO:0040012	regulation of locomotion
0.53	GO:0009615	response to virus
0.50	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.48	GO:0007271	synaptic transmission, cholinergic
0.48	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.48	GO:0006940	regulation of smooth muscle contraction
0.40	GO:1903523	negative regulation of blood circulation
0.38	GO:0046541	saliva secretion

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.61	GO:1990763	arrestin family protein binding
0.34	GO:0008144	drug binding

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.41	GO:0032280	symmetric synapse
0.39	GO:0043679	axon terminus
0.39	GO:0032279	asymmetric synapse
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.35	GO:0030665	clathrin-coated vesicle membrane

sp|P11030|ACBP_RAT
Acyl-CoA-binding protein
Search

DBI

0.62	Benzodiazepine receptor ligand

0.47	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.38	GO:0021670	lateral ventricle development
0.37	GO:0001662	behavioral fear response
0.37	GO:0032228	regulation of synaptic transmission, GABAergic
0.37	GO:0060291	long-term synaptic potentiation
0.37	GO:0001942	hair follicle development
0.37	GO:0018345	protein palmitoylation
0.37	GO:0007611	learning or memory
0.36	GO:0006641	triglyceride metabolic process
0.36	GO:0001300	chronological cell aging

0.82	GO:0000062	fatty-acyl-CoA binding
0.41	GO:0046983	protein dimerization activity
0.41	GO:0008289	lipid binding
0.37	GO:0030156	benzodiazepine receptor binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0008483	transaminase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0016853	isomerase activity

0.40	GO:0005794	Golgi apparatus
0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005576	extracellular region
0.37	GO:0008021	synaptic vesicle
0.35	GO:0043292	contractile fiber
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005739	mitochondrion
0.34	GO:0043209	myelin sheath
0.33	GO:0070013	intracellular organelle lumen

0.33

GO:0016746

sp|P11101|STP2_RAT
Nuclear transition protein 2
Search

TNP2

0.96	Nuclear transition protein 2

0.80	GO:0007283	spermatogenesis
0.70	GO:0030154	cell differentiation
0.69	GO:0007341	penetration of zona pellucida
0.68	GO:0007275	multicellular organism development
0.68	GO:0010954	positive regulation of protein processing
0.66	GO:0007340	acrosome reaction
0.64	GO:0043486	histone exchange
0.63	GO:0006997	nucleus organization
0.61	GO:0022412	cellular process involved in reproduction in multicellular organism
0.60	GO:0003006	developmental process involved in reproduction

0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding

0.75	GO:0000786	nucleosome
0.63	GO:0001673	male germ cell nucleus
0.59	GO:0000790	nuclear chromatin
0.43	GO:0005730	nucleolus

sp|P11167|GTR1_RAT
Solute carrier family 2, facilitated glucose transporter member 1
Search

SLC2A1

0.87	Solute carrier family 2, facilitated glucose transporter member 1

0.72	GO:1904659	glucose transmembrane transport
0.54	GO:0070837	dehydroascorbic acid transport
0.51	GO:0032868	response to insulin
0.51	GO:0071548	response to dexamethasone
0.51	GO:0042149	cellular response to glucose starvation
0.47	GO:0006461	protein complex assembly
0.41	GO:0002040	sprouting angiogenesis
0.40	GO:1904016	response to Thyroglobulin triiodothyronine
0.39	GO:0071260	cellular response to mechanical stimulus
0.39	GO:0071474	cellular hyperosmotic response

0.73	GO:0005355	glucose transmembrane transporter activity
0.54	GO:0043621	protein self-association
0.54	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.48	GO:0042802	identical protein binding
0.38	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0019900	kinase binding

0.54	GO:0001939	female pronucleus
0.52	GO:0030864	cortical actin cytoskeleton
0.52	GO:0030496	midbody
0.50	GO:0016323	basolateral plasma membrane
0.50	GO:0016324	apical plasma membrane
0.49	GO:0045121	membrane raft
0.47	GO:0031982	vesicle
0.46	GO:0005887	integral component of plasma membrane
0.45	GO:0005829	cytosol
0.39	GO:0014704	intercalated disc

sp|P11232|THIO_RAT
Thioredoxin
Search

TXN

0.50	Thioredoxin

0.74	GO:0006662	glycerol ether metabolic process
0.67	GO:0045454	cell redox homeostasis
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0046822	regulation of nucleocytoplasmic transport
0.49	GO:0051223	regulation of protein transport
0.49	GO:0043388	positive regulation of DNA binding
0.48	GO:0051457	maintenance of protein location in nucleus
0.47	GO:1900180	regulation of protein localization to nucleus
0.47	GO:0032386	regulation of intracellular transport
0.46	GO:1904950	negative regulation of establishment of protein localization

0.71	GO:0015035	protein disulfide oxidoreductase activity
0.46	GO:0015037	peptide disulfide oxidoreductase activity
0.46	GO:0004791	thioredoxin-disulfide reductase activity
0.46	GO:0047134	protein-disulfide reductase activity
0.44	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.43	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0005576	extracellular region
0.40	GO:0005739	mitochondrion
0.35	GO:0031982	vesicle
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon

0.46	EC:1.8.1.9	GO:0004791
0.46	KEGG:R02016	GO:0004791

sp|P11240|COX5A_RAT
Cytochrome c oxidase subunit 5A, mitochondrial
Search

COX5A

0.87	Cytochrome c oxidase polypeptide Va

0.61	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.41	GO:0006119	oxidative phosphorylation
0.41	GO:0009060	aerobic respiration
0.37	GO:0021522	spinal cord motor neuron differentiation
0.36	GO:0048568	embryonic organ development

0.63	GO:0015002	heme-copper terminal oxidase activity
0.63	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.62	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.40	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.51	GO:0043209	myelin sheath
0.51	GO:0045277	respiratory chain complex IV
0.50	GO:0098798	mitochondrial protein complex
0.37	GO:0070062	extracellular exosome

0.63

GO:0016676

sp|P11248|PRM2_RAT
Protamine-2
Search

PRM2

0.97	Protamine-2

0.82	GO:0007286	spermatid development
0.75	GO:0006323	DNA packaging
0.53	GO:0007275	multicellular organism development
0.49	GO:0006997	nucleus organization
0.38	GO:0006325	chromatin organization
0.38	GO:0065004	protein-DNA complex assembly

0.55	GO:0003677	DNA binding
0.49	GO:0046870	cadmium ion binding
0.40	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding

0.56	GO:0000786	nucleosome
0.49	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.35	GO:0031974	membrane-enclosed lumen

sp|P11250|RL34_RAT
60S ribosomal protein L34
Search

RPL34

0.73	Ribosomal protein L34

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.41	GO:0042254	ribosome biogenesis
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0016072	rRNA metabolic process

0.62	GO:0003735	structural constituent of ribosome
0.47	GO:0045296	cadherin binding
0.38	GO:0003723	RNA binding

0.60	GO:0005840	ribosome
0.42	GO:0044445	cytosolic part
0.41	GO:0005739	mitochondrion
0.38	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P11275|KCC2A_RAT
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Search

CAMK2A

0.97	Calcium/calmodulin-dependent protein kinase type II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.58	GO:0010666	positive regulation of cardiac muscle cell apoptotic process
0.56	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process
0.56	GO:0002931	response to ischemia
0.55	GO:0038166	angiotensin-activated signaling pathway
0.55	GO:0046928	regulation of neurotransmitter secretion
0.55	GO:0048168	regulation of neuronal synaptic plasticity
0.54	GO:0051928	positive regulation of calcium ion transport
0.54	GO:0048813	dendrite morphogenesis
0.54	GO:0018209	peptidyl-serine modification

0.81	GO:0004683	calmodulin-dependent protein kinase activity
0.77	GO:0005516	calmodulin binding
0.56	GO:0035254	glutamate receptor binding
0.56	GO:0009931	calcium-dependent protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.50	GO:0042803	protein homodimerization activity
0.35	GO:0032794	GTPase activating protein binding

0.54	GO:0014069	postsynaptic density
0.45	GO:0043005	neuron projection
0.44	GO:0005739	mitochondrion
0.39	GO:0042734	presynaptic membrane
0.37	GO:0030054	cell junction
0.36	GO:0099524	postsynaptic cytosol
0.35	GO:0099634	postsynaptic specialization membrane
0.35	GO:0030666	endocytic vesicle membrane
0.34	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.34	GO:0043025	neuronal cell body

0.81	EC:2.7.11.17	GO:0004683
0.33	KEGG:R00162	GO:0004707

sp|P11345|RAF1_RAT
RAF proto-oncogene serine/threonine-protein kinase
Search

RAF1

0.92	RAF proto-oncogene serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.49	GO:0000186	activation of MAPKK activity
0.48	GO:0071550	death-inducing signaling complex assembly
0.47	GO:0035773	insulin secretion involved in cellular response to glucose stimulus
0.47	GO:0035994	response to muscle stretch
0.47	GO:0043066	negative regulation of apoptotic process
0.47	GO:0048011	neurotrophin TRK receptor signaling pathway
0.47	GO:0007190	activation of adenylate cyclase activity
0.46	GO:0030878	thyroid gland development

0.77	GO:0005057	signal transducer activity, downstream of receptor
0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.47	GO:0031434	mitogen-activated protein kinase kinase binding
0.44	GO:0010856	adenylate cyclase activator activity
0.43	GO:0031267	small GTPase binding

0.46	GO:0031143	pseudopodium
0.44	GO:0005622	intracellular
0.41	GO:0012505	endomembrane system
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0005886	plasma membrane
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0044422	organelle part
0.35	GO:0098805	whole membrane
0.35	GO:0019867	outer membrane
0.34	GO:0031975	envelope

0.69

GO:0004674

sp|P11348|DHPR_RAT
Dihydropteridine reductase
Search

QDPR

0.64	Quinoid dihydropteridine reductase a

0.51	GO:0055114	oxidation-reduction process
0.41	GO:0010288	response to lead ion
0.41	GO:0010044	response to aluminum ion
0.41	GO:0046146	tetrahydrobiopterin metabolic process
0.41	GO:0034312	diol biosynthetic process
0.41	GO:0033762	response to glucagon
0.40	GO:0001889	liver development
0.39	GO:0042559	pteridine-containing compound biosynthetic process
0.39	GO:0035690	cellular response to drug
0.39	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process

0.53	GO:0016491	oxidoreductase activity
0.41	GO:0070404	NADH binding
0.39	GO:0070402	NADPH binding
0.38	GO:0042803	protein homodimerization activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.32	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0005524	ATP binding

0.45	GO:0005739	mitochondrion
0.39	GO:0043005	neuron projection
0.37	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.53

EC:1

GO:0016491

sp|P11384|SECR_RAT
Secretin
Search

SCT

0.54

Secretin

0.76	GO:0010469	regulation of receptor activity
0.56	GO:1903640	negative regulation of gastrin-induced gastric acid secretion
0.55	GO:0021542	dentate gyrus development
0.55	GO:0090274	positive regulation of somatostatin secretion
0.55	GO:0097150	neuronal stem cell population maintenance
0.54	GO:0090187	positive regulation of pancreatic juice secretion
0.54	GO:0008542	visual learning
0.53	GO:0043524	negative regulation of neuron apoptotic process
0.52	GO:0043950	positive regulation of cAMP-mediated signaling
0.51	GO:0048566	embryonic digestive tract development

0.79	GO:0005179	hormone activity
0.50	GO:0047485	protein N-terminus binding

0.66

GO:0005576

extracellular region

sp|P11442|CLH1_RAT
Clathrin heavy chain 1
Search

CLTC

0.65	Clathrin heavy chain

0.82	GO:0048268	clathrin coat assembly
0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.40	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.38	GO:0033572	transferrin transport
0.38	GO:1903077	negative regulation of protein localization to plasma membrane
0.37	GO:0060236	regulation of mitotic spindle organization
0.37	GO:0006914	autophagy
0.37	GO:0043112	receptor metabolic process
0.37	GO:0016482	cytosolic transport

0.85	GO:0032051	clathrin light chain binding
0.61	GO:0005198	structural molecule activity
0.46	GO:0019901	protein kinase binding
0.40	GO:0097718	disordered domain specific binding
0.38	GO:1990381	ubiquitin-specific protease binding
0.38	GO:0050750	low-density lipoprotein particle receptor binding
0.36	GO:0003725	double-stranded RNA binding
0.35	GO:0004386	helicase activity
0.35	GO:1990763	arrestin family protein binding
0.35	GO:0030506	ankyrin binding

0.84	GO:0071439	clathrin complex
0.82	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.82	GO:0030132	clathrin coat of coated pit
0.47	GO:0043209	myelin sheath
0.47	GO:0072686	mitotic spindle
0.46	GO:0005764	lysosome
0.45	GO:0005768	endosome
0.40	GO:0005739	mitochondrion
0.38	GO:0042470	melanosome
0.37	GO:0005876	spindle microtubule

sp|P11466|OCTC_RAT
Peroxisomal carnitine O-octanoyltransferase
Search

CROT

0.97	Peroxisomal carnitine O-octanoyltransferase

0.60	GO:0051791	medium-chain fatty acid metabolic process
0.55	GO:0009437	carnitine metabolic process
0.54	GO:0015908	fatty acid transport
0.53	GO:0006635	fatty acid beta-oxidation
0.51	GO:0015936	coenzyme A metabolic process
0.45	GO:0006091	generation of precursor metabolites and energy
0.35	GO:0010243	response to organonitrogen compound
0.34	GO:0042493	response to drug

0.63	GO:0008458	carnitine O-octanoyltransferase activity
0.51	GO:0005102	receptor binding
0.39	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0003677	DNA binding

0.53	GO:0005777	peroxisome
0.44	GO:0005739	mitochondrion
0.35	GO:0031907	microbody lumen
0.30	GO:0016020	membrane

0.63	EC:2.3.1.137	GO:0008458
0.63	KEGG:R03779	GO:0008458

sp|P11475|ERR2_RAT
Steroid hormone receptor ERR2
Search

ESRRB

0.94	Estrogen-related receptor beta type 1

0.75	GO:0043401	steroid hormone mediated signaling pathway
0.61	GO:0048384	retinoic acid receptor signaling pathway
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:0019827	stem cell population maintenance
0.55	GO:0010468	regulation of gene expression
0.46	GO:0045935	positive regulation of nucleobase-containing compound metabolic process
0.46	GO:0010557	positive regulation of macromolecule biosynthetic process
0.46	GO:0031328	positive regulation of cellular biosynthetic process

0.78	GO:0005496	steroid binding
0.77	GO:0003707	steroid hormone receptor activity
0.62	GO:0043565	sequence-specific DNA binding
0.62	GO:0003708	retinoic acid receptor activity
0.61	GO:0008270	zinc ion binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.38	GO:0050682	AF-2 domain binding
0.35	GO:0005516	calmodulin binding

0.59	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P11497|ACACA_RAT
Acetyl-CoA carboxylase 1
Search

ACACA

0.55	Acetyl-coenzyme A carboxylase alpha

0.69	GO:0006633	fatty acid biosynthetic process
0.57	GO:0044268	multicellular organismal protein metabolic process
0.55	GO:0071380	cellular response to prostaglandin E stimulus
0.54	GO:0051289	protein homotetramerization
0.53	GO:0001894	tissue homeostasis
0.52	GO:0055088	lipid homeostasis
0.50	GO:0006084	acetyl-CoA metabolic process
0.41	GO:2001295	malonyl-CoA biosynthetic process
0.37	GO:0006853	carnitine shuttle
0.36	GO:0045540	regulation of cholesterol biosynthetic process

0.74	GO:0003989	acetyl-CoA carboxylase activity
0.74	GO:0004075	biotin carboxylase activity
0.54	GO:0005524	ATP binding
0.52	GO:0046872	metal ion binding
0.49	GO:0042802	identical protein binding
0.36	GO:0009374	biotin binding
0.35	GO:0032810	sterol response element binding
0.35	GO:0050692	DBD domain binding
0.34	GO:0046966	thyroid hormone receptor binding

0.53	GO:0001650	fibrillar center
0.49	GO:0015629	actin cytoskeleton
0.48	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:6.4.1.2

GO:0003989

sp|P11505|AT2B1_RAT
Plasma membrane calcium-transporting ATPase 1
Search

ATP2B1

0.60	Plasma membrane calcium-transporting ATPase 1

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.57	GO:1990034	calcium ion export across plasma membrane
0.53	GO:0006874	cellular calcium ion homeostasis
0.40	GO:0007423	sensory organ development
0.40	GO:0034505	tooth mineralization
0.39	GO:0048916	posterior lateral line development
0.39	GO:0071386	cellular response to corticosterone stimulus
0.39	GO:0007399	nervous system development
0.39	GO:0030282	bone mineralization

0.80	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0030165	PDZ domain binding
0.39	GO:0005516	calmodulin binding
0.36	GO:0036487	nitric-oxide synthase inhibitor activity
0.36	GO:0030346	protein phosphatase 2B binding
0.36	GO:0050998	nitric-oxide synthase binding

0.44	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.38	GO:0043197	dendritic spine
0.37	GO:0043025	neuronal cell body
0.37	GO:0070062	extracellular exosome
0.37	GO:0098857	membrane microdomain
0.37	GO:0045177	apical part of cell
0.37	GO:0031252	cell leading edge
0.37	GO:0098562	cytoplasmic side of membrane
0.35	GO:0036126	sperm flagellum

0.80

GO:0005388

sp|P11506|AT2B2_RAT
Plasma membrane calcium-transporting ATPase 2
Search

ATP2B2

0.59	Plasma membrane calcium-transporting ATPase 2

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.53	GO:0006874	cellular calcium ion homeostasis
0.52	GO:0007605	sensory perception of sound
0.50	GO:0030182	neuron differentiation
0.38	GO:0045299	otolith mineralization
0.37	GO:0021684	cerebellar granular layer formation
0.37	GO:0021694	cerebellar Purkinje cell layer formation
0.37	GO:0042428	serotonin metabolic process
0.37	GO:0007595	lactation

0.80	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.47	GO:0030165	PDZ domain binding
0.38	GO:0005516	calmodulin binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0030899	calcium-dependent ATPase activity
0.36	GO:0005509	calcium ion binding

0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0005737	cytoplasm
0.38	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0045202	synapse
0.36	GO:0030054	cell junction
0.36	GO:0070062	extracellular exosome
0.36	GO:0005929	cilium
0.36	GO:0016324	apical plasma membrane
0.36	GO:0043025	neuronal cell body
0.35	GO:0044298	cell body membrane

0.80

GO:0005388

sp|P11507|AT2A2_RAT
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Search

ATP2A2

0.54	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.57	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration
0.57	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter
0.57	GO:0033292	T-tubule organization
0.56	GO:0014883	transition between fast and slow fiber
0.56	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.55	GO:0008016	regulation of heart contraction
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0014887	cardiac muscle adaptation

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0044548	S100 protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019899	enzyme binding
0.47	GO:0005509	calcium ion binding
0.39	GO:0031775	lutropin-choriogonadotropic hormone receptor binding
0.38	GO:0008022	protein C-terminus binding

0.56	GO:0097470	ribbon synapse
0.54	GO:0016529	sarcoplasmic reticulum
0.48	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005654	nucleoplasm
0.39	GO:0090534	calcium ion-transporting ATPase complex
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0014704	intercalated disc
0.37	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0012506	vesicle membrane

0.80

GO:0005388

sp|P11510|CP2CC_RAT
Cytochrome P450 2C12, female-specific
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.60	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0042738	exogenous drug catabolic process
0.45	GO:0043651	linoleic acid metabolic process
0.44	GO:0016098	monoterpenoid metabolic process
0.44	GO:0008202	steroid metabolic process
0.43	GO:0070988	demethylation
0.42	GO:0002933	lipid hydroxylation
0.38	GO:0006805	xenobiotic metabolic process
0.38	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.48	GO:0034875	caffeine oxidase activity
0.38	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding

0.47	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P11517|HBB2_RAT
Hemoglobin subunit beta-2
Search

0.79	Hemoglobin beta chain subunit

0.79	GO:0015671	oxygen transport
0.42	GO:0070293	renal absorption
0.41	GO:0051291	protein heterooligomerization
0.41	GO:0042542	response to hydrogen peroxide
0.40	GO:0010942	positive regulation of cell death
0.39	GO:0042744	hydrogen peroxide catabolic process
0.39	GO:0098869	cellular oxidant detoxification
0.38	GO:0048821	erythrocyte development
0.37	GO:0010999	regulation of eIF2 alpha phosphorylation by heme
0.37	GO:0070527	platelet aggregation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0031720	haptoglobin binding
0.43	GO:0030492	hemoglobin binding
0.39	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.45	GO:0031838	haptoglobin-hemoglobin complex
0.41	GO:0005615	extracellular space
0.36	GO:0043209	myelin sheath
0.36	GO:1903561	extracellular vesicle
0.35	GO:0071682	endocytic vesicle lumen
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen

0.39	EC:1.11.1.7	GO:0004601
0.39	KEGG:R03532	GO:0004601

sp|P11530|DMD_RAT
Dystrophin
Search

DMD

0.70	Dystrophin

0.52	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
0.51	GO:0021629	olfactory nerve structural organization
0.51	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.51	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.50	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.50	GO:0008065	establishment of blood-nerve barrier
0.50	GO:0035994	response to muscle stretch
0.50	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.50	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.50	GO:0045213	neurotransmitter receptor metabolic process

0.86	GO:0002162	dystroglycan binding
0.74	GO:0003779	actin binding
0.60	GO:0008270	zinc ion binding
0.51	GO:0050998	nitric-oxide synthase binding
0.43	GO:0017166	vinculin binding
0.43	GO:0005521	lamin binding
0.43	GO:0008307	structural constituent of muscle
0.42	GO:0030165	PDZ domain binding
0.42	GO:0005178	integrin binding
0.42	GO:0017022	myosin binding

0.63	GO:0045211	postsynaptic membrane
0.60	GO:0030054	cell junction
0.56	GO:0005856	cytoskeleton
0.50	GO:0042383	sarcolemma
0.48	GO:0044306	neuron projection terminus
0.48	GO:0030018	Z disc
0.48	GO:0016010	dystrophin-associated glycoprotein complex
0.47	GO:0098857	membrane microdomain
0.44	GO:0099617	matrix side of mitochondrial inner membrane
0.43	GO:0097449	astrocyte projection

sp|P11598|PDIA3_RAT
Protein disulfide-isomerase A3
Search

PDIA3

0.62	Protein disulfide-isomerase A3

0.69	GO:0045454	cell redox homeostasis
0.68	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.64	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0006457	protein folding
0.53	GO:1904148	cellular response to nonylphenol
0.52	GO:1901423	response to benzene
0.52	GO:1903334	positive regulation of protein folding
0.51	GO:0033595	response to genistein
0.49	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.49	GO:0071305	cellular response to vitamin D

0.72	GO:0003756	protein disulfide isomerase activity
0.64	GO:0015037	peptide disulfide oxidoreductase activity
0.59	GO:0042802	identical protein binding
0.50	GO:0019153	protein-disulfide reductase (glutathione) activity
0.49	GO:0042288	MHC class I protein binding
0.46	GO:0004629	phospholipase C activity
0.44	GO:0004197	cysteine-type endopeptidase activity
0.43	GO:0003723	RNA binding

0.74	GO:0042470	melanosome
0.73	GO:0005788	endoplasmic reticulum lumen
0.65	GO:0043209	myelin sheath
0.63	GO:0009986	cell surface
0.59	GO:0005615	extracellular space
0.53	GO:0005925	focal adhesion
0.53	GO:1903561	extracellular vesicle
0.49	GO:0042825	TAP complex
0.49	GO:0005790	smooth endoplasmic reticulum
0.47	GO:0055038	recycling endosome membrane

0.72

EC:5.3.4.1

GO:0003756

sp|P11608|ATP8_RAT
ATP synthase protein 8
Search

ATP8

0.49	ATP synthase protein 8

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.35	GO:0055093	response to hyperoxia
0.32	GO:0055114	oxidation-reduction process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016787	hydrolase activity
0.32	GO:0016491	oxidoreductase activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.34

GO:0016787

sp|P11654|PO210_RAT
Nuclear pore membrane glycoprotein 210
Search

NUP210

0.96	Nuclear pore membrane glycoprotein 210

0.39	GO:0051028	mRNA transport
0.37	GO:0007077	mitotic nuclear envelope disassembly
0.37	GO:0015031	protein transport
0.36	GO:1900034	regulation of cellular response to heat
0.36	GO:0006110	regulation of glycolytic process
0.36	GO:0051031	tRNA transport
0.36	GO:0060964	regulation of gene silencing by miRNA
0.36	GO:0097064	ncRNA export from nucleus
0.36	GO:0016925	protein sumoylation
0.35	GO:0071166	ribonucleoprotein complex localization

0.37	GO:0046983	protein dimerization activity
0.36	GO:0017056	structural constituent of nuclear pore

0.52	GO:0005635	nuclear envelope
0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.36	GO:0043234	protein complex
0.34	GO:0044215	other organism
0.30	GO:0031224	intrinsic component of membrane

sp|P11661|NU5M_RAT
NADH-ubiquinone oxidoreductase chain 5
Search

ND5

0.48	NADH-ubiquinone oxidoreductase chain 5

0.69	GO:0042773	ATP synthesis coupled electron transport
0.35	GO:0042542	response to hydrogen peroxide
0.35	GO:0001666	response to hypoxia
0.34	GO:0010243	response to organonitrogen compound

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.41	GO:0030964	NADH dehydrogenase complex
0.39	GO:0098798	mitochondrial protein complex
0.39	GO:1990204	oxidoreductase complex
0.37	GO:0098796	membrane protein complex
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P11662|NU2M_RAT
NADH-ubiquinone oxidoreductase chain 2
Search

ND2

0.42	NADH-ubiquinone oxidoreductase chain 2

0.75	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.37	GO:0072593	reactive oxygen species metabolic process

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.35	GO:0035255	ionotropic glutamate receptor binding
0.34	GO:0019901	protein kinase binding

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.40	GO:0030964	NADH dehydrogenase complex
0.38	GO:0098798	mitochondrial protein complex
0.38	GO:1990204	oxidoreductase complex
0.36	GO:0098796	membrane protein complex
0.35	GO:0014069	postsynaptic density
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P11685|PSPC_RAT
Pulmonary surfactant-associated protein C
Search

SFTPC

0.97	Pulmonary surfactant-associated protein C

0.85	GO:0007585	respiratory gaseous exchange
0.41	GO:0050828	regulation of liquid surface tension
0.41	GO:0033189	response to vitamin A
0.41	GO:0071732	cellular response to nitric oxide
0.41	GO:0055093	response to hyperoxia
0.41	GO:0070741	response to interleukin-6
0.40	GO:0051591	response to cAMP
0.40	GO:0071260	cellular response to mechanical stimulus
0.40	GO:0032526	response to retinoic acid
0.40	GO:0051384	response to glucocorticoid

0.54	GO:0042802	identical protein binding
0.37	GO:0046983	protein dimerization activity

0.66	GO:0005576	extracellular region
0.44	GO:0042599	lamellar body
0.43	GO:0005771	multivesicular body
0.41	GO:0031906	late endosome lumen
0.39	GO:0045334	clathrin-coated endocytic vesicle
0.37	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P11711|CP2A1_RAT
Cytochrome P450 2A1
Search

0.61	Cytochrome P450 family 2 subfamily A member 6

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0019373	epoxygenase P450 pathway
0.42	GO:0009804	coumarin metabolic process
0.42	GO:0090420	naphthalene-containing compound metabolic process
0.40	GO:0035634	response to stilbenoid
0.39	GO:0071276	cellular response to cadmium ion
0.39	GO:0007608	sensory perception of smell
0.37	GO:0009636	response to toxic substance
0.37	GO:0042168	heme metabolic process
0.36	GO:0017144	drug metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.51	GO:0008392	arachidonic acid epoxygenase activity
0.50	GO:0008395	steroid hydroxylase activity
0.42	GO:0019825	oxygen binding

0.45	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P11715|CP17A_RAT
Steroid 17-alpha-hydroxylase/17,20 lyase
Search

CYP17A1

0.94	steroid 17-alpha-hydroxylase/17,20 lyase precursor

0.71	GO:0006694	steroid biosynthetic process
0.67	GO:0042448	progesterone metabolic process
0.66	GO:0007548	sex differentiation
0.60	GO:0042446	hormone biosynthetic process
0.58	GO:0008211	glucocorticoid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0042181	ketone biosynthetic process
0.38	GO:0008209	androgen metabolic process
0.37	GO:0018879	biphenyl metabolic process
0.37	GO:0018963	phthalate metabolic process

0.84	GO:0004508	steroid 17-alpha-monooxygenase activity
0.84	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.35	GO:0019825	oxygen binding

0.54	GO:0043025	neuronal cell body
0.54	GO:0030424	axon
0.44	GO:0005739	mitochondrion
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:1.14.99.9

GO:0004508

sp|P11730|KCC2G_RAT
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Search

CAMK2G

0.89	Calcium/calmodulin-dependent protein kinase type II subunit gamma

0.62	GO:0006468	protein phosphorylation
0.52	GO:1901897	regulation of relaxation of cardiac muscle
0.49	GO:0000082	G1/S transition of mitotic cell cycle
0.46	GO:0006816	calcium ion transport
0.45	GO:0051259	protein oligomerization
0.44	GO:0018210	peptidyl-threonine modification
0.43	GO:0018209	peptidyl-serine modification
0.42	GO:0007399	nervous system development
0.41	GO:0030154	cell differentiation
0.39	GO:0035556	intracellular signal transduction

0.80	GO:0004683	calmodulin-dependent protein kinase activity
0.76	GO:0005516	calmodulin binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042803	protein homodimerization activity
0.35	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004707	MAP kinase activity

0.49	GO:0014069	postsynaptic density
0.42	GO:0043005	neuron projection
0.39	GO:0033017	sarcoplasmic reticulum membrane
0.34	GO:0030666	endocytic vesicle membrane
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80	EC:2.7.11.17	GO:0004683
0.34	KEGG:R00162	GO:0004707

sp|P11762|LEG1_RAT
Galectin-1
Search

LGALS1

0.66

Galectin

0.56	GO:0046598	positive regulation of viral entry into host cell
0.56	GO:0002317	plasma cell differentiation
0.54	GO:0031295	T cell costimulation
0.54	GO:0045445	myoblast differentiation
0.44	GO:0006915	apoptotic process
0.41	GO:0034120	positive regulation of erythrocyte aggregation
0.41	GO:0035900	response to isolation stress
0.40	GO:0048678	response to axon injury
0.39	GO:0010812	negative regulation of cell-substrate adhesion
0.39	GO:0071333	cellular response to glucose stimulus

0.70	GO:0030246	carbohydrate binding
0.40	GO:0043236	laminin binding
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0004871	signal transducer activity
0.34	GO:0003723	RNA binding
0.32	GO:0036094	small molecule binding

0.51	GO:0031012	extracellular matrix
0.49	GO:0005615	extracellular space
0.38	GO:0009986	cell surface
0.37	GO:1903561	extracellular vesicle
0.37	GO:0005622	intracellular
0.34	GO:0012505	endomembrane system
0.34	GO:0043233	organelle lumen

sp|P11883|AL3A1_RAT
Aldehyde dehydrogenase, dimeric NADP-preferring
Search

ALDH3A1

0.43	Aldehyde dehydrogenase, dimeric NADP-preferring

0.66	GO:0006081	cellular aldehyde metabolic process
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0033306	phytol metabolic process
0.47	GO:0007422	peripheral nervous system development
0.46	GO:0008544	epidermis development
0.45	GO:0007417	central nervous system development
0.37	GO:0051591	response to cAMP
0.37	GO:0051384	response to glucocorticoid
0.37	GO:0001666	response to hypoxia
0.37	GO:0007584	response to nutrient

0.76	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.55	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.53	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.48	GO:0046577	long-chain-alcohol oxidase activity
0.46	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity
0.33	GO:0005515	protein binding

0.49	GO:0005783	endoplasmic reticulum
0.46	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0031090	organelle membrane
0.39	GO:0005740	mitochondrial envelope
0.37	GO:0005615	extracellular space
0.36	GO:0042579	microbody
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:1903561	extracellular vesicle

0.76

EC:1.2.1.5

GO:0004030

sp|P11884|ALDH2_RAT
Aldehyde dehydrogenase, mitochondrial
Search

ALDH2

0.39	Mitochondrial aldehyde dehydrogenase 2

0.52	GO:0055114	oxidation-reduction process
0.46	GO:0006068	ethanol catabolic process
0.36	GO:0033574	response to testosterone
0.36	GO:0055093	response to hyperoxia
0.36	GO:0032570	response to progesterone
0.36	GO:0035094	response to nicotine
0.36	GO:0071398	cellular response to fatty acid
0.36	GO:0032355	response to estradiol
0.36	GO:0001889	liver development
0.35	GO:0032496	response to lipopolysaccharide

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.39	GO:0051287	NAD binding
0.35	GO:0005515	protein binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0043168	anion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.45	GO:0005739	mitochondrion
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome

0.69

EC:1.2.1

GO:0016620

sp|P11915|NLTP_RAT
Non-specific lipid-transfer protein
Search

SCP2

0.61	Sterol carrier protein 2

0.61	GO:1901373	lipid hydroperoxide transport
0.60	GO:0032379	positive regulation of intracellular lipid transport
0.59	GO:0032380	regulation of intracellular sterol transport
0.58	GO:0032376	positive regulation of cholesterol transport
0.53	GO:0007031	peroxisome organization
0.45	GO:0015918	sterol transport
0.43	GO:0015914	phospholipid transport
0.43	GO:0006694	steroid biosynthetic process
0.40	GO:0032959	inositol trisphosphate biosynthetic process
0.39	GO:0042448	progesterone metabolic process

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.60	GO:0070538	oleic acid binding
0.59	GO:0036042	long-chain fatty acyl-CoA binding
0.56	GO:0032934	sterol binding
0.54	GO:0043178	alcohol binding
0.50	GO:0005102	receptor binding
0.46	GO:0015248	sterol transporter activity
0.39	GO:0008526	phosphatidylinositol transporter activity
0.37	GO:0005518	collagen binding
0.36	GO:1904121	phosphatidylethanolamine transporter activity

0.52	GO:0005777	peroxisome
0.48	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.44	GO:0043234	protein complex
0.38	GO:0005615	extracellular space
0.37	GO:0031907	microbody lumen
0.36	GO:1903561	extracellular vesicle
0.36	GO:0031012	extracellular matrix
0.35	GO:0031312	extrinsic component of organelle membrane
0.35	GO:0031968	organelle outer membrane

0.64

EC:2.3.1

GO:0016747

sp|P11950|CX6C1_RAT
Cytochrome c oxidase subunit 6C-1
Search

COX6C

0.96	Cytochrome c oxidase polypeptide VIc

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.50	GO:0031966	mitochondrial membrane
0.50	GO:0019866	organelle inner membrane
0.38	GO:0045277	respiratory chain complex IV
0.36	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9

GO:0016675

sp|P11951|CX6C2_RAT
Cytochrome c oxidase subunit 6C-2
Search

COX6C

0.95	Cytochrome c oxidase polypeptide VIc

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.49	GO:0031966	mitochondrial membrane
0.49	GO:0019866	organelle inner membrane
0.38	GO:0045277	respiratory chain complex IV
0.36	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9

GO:0016675

sp|P11960|ODBA_RAT
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (Fragment)
Search

BCKDHA

0.87	Branched chain keto acid dehydrogenase E1 alpha polypeptide

0.81	GO:0009083	branched-chain amino acid catabolic process
0.53	GO:0055114	oxidation-reduction process

0.83	GO:0003826	alpha-ketoacid dehydrogenase activity
0.83	GO:0003863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity

0.83

EC:1.2.4.4

GO:0003863

sp|P11962|GLHA_RAT
Glycoprotein hormones alpha chain
Search

CGA

0.93	Glycoprotein hormones alpha chain

0.76	GO:0010469	regulation of receptor activity
0.53	GO:0046884	follicle-stimulating hormone secretion
0.53	GO:0032275	luteinizing hormone secretion
0.52	GO:0006590	thyroid hormone generation
0.51	GO:0030878	thyroid gland development
0.51	GO:0046621	negative regulation of organ growth
0.49	GO:0008406	gonad development
0.48	GO:0048589	developmental growth
0.47	GO:0032870	cellular response to hormone stimulus

0.79	GO:0005179	hormone activity
0.44	GO:0046982	protein heterodimerization activity
0.36	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P11980|KPYM_RAT
Pyruvate kinase PKM
Search

PKM

0.46	Pyruvate kinase PKM

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.47	GO:0012501	programmed cell death
0.47	GO:0032868	response to insulin
0.46	GO:0071375	cellular response to peptide hormone stimulus
0.39	GO:0014870	response to muscle inactivity
0.38	GO:0043403	skeletal muscle tissue regeneration
0.38	GO:0031100	animal organ regeneration

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.49	GO:0045296	cadherin binding
0.39	GO:0070324	thyroid hormone binding
0.37	GO:0023026	MHC class II protein complex binding
0.37	GO:0043531	ADP binding
0.36	GO:0042802	identical protein binding
0.36	GO:0005524	ATP binding

0.49	GO:0043209	myelin sheath
0.47	GO:0005929	cilium
0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.40	GO:1902912	pyruvate kinase complex
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.78

EC:2.7.1.40

GO:0004743

sp|P12001|RL18_RAT
60S ribosomal protein L18
Search

RPL18

0.73	Ribosomal protein L18

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0097421	liver regeneration
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.48	GO:0005844	polysome
0.47	GO:0044445	cytosolic part
0.44	GO:0005730	nucleolus
0.43	GO:0005783	endoplasmic reticulum
0.36	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

sp|P12007|IVD_RAT
Isovaleryl-CoA dehydrogenase, mitochondrial
Search

IVD

0.52	Isovaleryl Coenzyme A dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.42	GO:0006552	leucine catabolic process
0.37	GO:0009062	fatty acid catabolic process
0.36	GO:0030258	lipid modification
0.34	GO:0051260	protein homooligomerization
0.33	GO:0006508	proteolysis
0.33	GO:0044257	cellular protein catabolic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0004175	endopeptidase activity
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0003735	structural constituent of ribosome

0.47	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.33	GO:0005839	proteasome core complex
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:1.3.99.3

GO:0003995

sp|P12020|CRIS1_RAT
Cysteine-rich secretory protein 1
Search

0.95	Cysteine-rich secretory protein A

0.40	GO:0019953	sexual reproduction
0.39	GO:0060046	regulation of acrosome reaction
0.39	GO:0009988	cell-cell recognition
0.38	GO:0098609	cell-cell adhesion
0.37	GO:0048609	multicellular organismal reproductive process
0.36	GO:0065009	regulation of molecular function
0.35	GO:0009405	pathogenesis
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0045087	innate immune response
0.32	GO:0006757	ATP generation from ADP

0.39	GO:0005246	calcium channel regulator activity
0.36	GO:0090729	toxin activity
0.32	GO:0004618	phosphoglycerate kinase activity
0.32	GO:0005216	ion channel activity

0.66	GO:0005576	extracellular region
0.45	GO:0042581	specific granule
0.36	GO:0030133	transport vesicle
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0034774	secretory granule lumen
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32	EC:2.7.2.3	GO:0004618
0.32	KEGG:R01512	GO:0004618

sp|P12075|COX5B_RAT
Cytochrome c oxidase subunit 5B, mitochondrial
Search

COX5B

0.86	Cytochrome c oxidase polypeptide Vb

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.48	GO:0006839	mitochondrial transport
0.45	GO:0006754	ATP biosynthetic process
0.44	GO:0046907	intracellular transport
0.43	GO:0006119	oxidative phosphorylation
0.43	GO:0009060	aerobic respiration
0.35	GO:0007585	respiratory gaseous exchange
0.35	GO:0043434	response to peptide hormone
0.35	GO:0033617	mitochondrial respiratory chain complex IV assembly

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.62	GO:0044429	mitochondrial part
0.62	GO:0031967	organelle envelope
0.47	GO:0045277	respiratory chain complex IV
0.43	GO:0031090	organelle membrane
0.37	GO:0043209	myelin sheath
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P12336|GTR2_RAT
Solute carrier family 2, facilitated glucose transporter member 2
Search

SLC2A2

0.95	Faciliated glucose transporter 2

0.67	GO:0008643	carbohydrate transport
0.62	GO:0070837	dehydroascorbic acid transport
0.54	GO:0055085	transmembrane transport
0.43	GO:0001889	liver development
0.42	GO:0007420	brain development
0.37	GO:0002040	sprouting angiogenesis
0.37	GO:0061300	cerebellum vasculature development
0.36	GO:0009758	carbohydrate utilization
0.36	GO:0001885	endothelial cell development
0.36	GO:0031018	endocrine pancreas development

0.67	GO:0005355	glucose transmembrane transporter activity
0.62	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.36	GO:0005158	insulin receptor binding

0.57	GO:0005903	brush border
0.56	GO:0016324	apical plasma membrane
0.53	GO:0005911	cell-cell junction
0.40	GO:0005737	cytoplasm
0.36	GO:0016323	basolateral plasma membrane
0.36	GO:0031253	cell projection membrane
0.35	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0005887	integral component of plasma membrane

sp|P12346|TRFE_RAT
Serotransferrin
Search

0.48	Lactotransferrin

0.57	GO:0043086	negative regulation of catalytic activity
0.56	GO:1900229	negative regulation of single-species biofilm formation in or on host organism
0.55	GO:1902732	positive regulation of chondrocyte proliferation
0.55	GO:0044793	negative regulation by host of viral process
0.55	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.55	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
0.55	GO:0002227	innate immune response in mucosa
0.54	GO:0033690	positive regulation of osteoblast proliferation
0.54	GO:0019732	antifungal humoral response
0.53	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

0.58	GO:0004857	enzyme inhibitor activity
0.53	GO:0015091	ferric iron transmembrane transporter activity
0.52	GO:0043539	protein serine/threonine kinase activator activity
0.51	GO:0008201	heparin binding
0.51	GO:0001530	lipopolysaccharide binding
0.50	GO:0008199	ferric iron binding
0.49	GO:0061135	endopeptidase regulator activity
0.46	GO:0004252	serine-type endopeptidase activity
0.30	GO:1990459	transferrin receptor binding
0.30	GO:0008198	ferrous iron binding

0.69	GO:0005615	extracellular space
0.53	GO:0042581	specific granule
0.48	GO:0009986	cell surface
0.45	GO:0044218	other organism cell membrane
0.42	GO:0043234	protein complex
0.30	GO:0051286	cell tip
0.30	GO:0043230	extracellular organelle
0.30	GO:0098590	plasma membrane region
0.30	GO:0098805	whole membrane
0.30	GO:0055037	recycling endosome

0.46

GO:0004252

sp|P12368|KAP2_RAT
cAMP-dependent protein kinase type II-alpha regulatory subunit
Search

PRKAR2A

0.94	cAMP-dependent protein kinase type II-alpha regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.56	GO:0033673	negative regulation of kinase activity
0.53	GO:0001933	negative regulation of protein phosphorylation
0.51	GO:0016310	phosphorylation
0.45	GO:0007612	learning
0.41	GO:0006631	fatty acid metabolic process
0.39	GO:0097338	response to clozapine
0.36	GO:1904146	positive regulation of meiotic cell cycle process involved in oocyte maturation
0.35	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0003091	renal water homeostasis

0.84	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.59	GO:0034236	protein kinase A catalytic subunit binding
0.59	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.55	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0016301	kinase activity
0.50	GO:0019904	protein domain specific binding
0.36	GO:0031698	beta-2 adrenergic receptor binding
0.34	GO:0005476	carnitine:acyl carnitine antiporter activity
0.34	GO:0015226	carnitine transmembrane transporter activity

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.54	GO:0044441	ciliary part
0.54	GO:0005813	centrosome
0.53	GO:0031588	nucleotide-activated protein kinase complex
0.53	GO:0044853	plasma membrane raft
0.52	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.46	GO:0043198	dendritic shaft
0.46	GO:0043197	dendritic spine
0.37	GO:0070062	extracellular exosome
0.37	GO:0048471	perinuclear region of cytoplasm

sp|P12369|KAP3_RAT
cAMP-dependent protein kinase type II-beta regulatory subunit
Search

PRKAR2B

0.97	cAMP-dependent protein kinase type II-beta regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.57	GO:0033673	negative regulation of kinase activity
0.55	GO:0007612	learning
0.54	GO:0001933	negative regulation of protein phosphorylation
0.51	GO:0016310	phosphorylation
0.48	GO:0006631	fatty acid metabolic process
0.42	GO:0097338	response to clozapine
0.37	GO:0071377	cellular response to glucagon stimulus
0.37	GO:0003091	renal water homeostasis
0.36	GO:0007596	blood coagulation

0.85	GO:0008603	cAMP-dependent protein kinase regulator activity
0.84	GO:0030552	cAMP binding
0.61	GO:0034236	protein kinase A catalytic subunit binding
0.61	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.56	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0016301	kinase activity
0.46	GO:0019904	protein domain specific binding
0.33	GO:0003735	structural constituent of ribosome

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.56	GO:0097546	ciliary base
0.56	GO:0043198	dendritic shaft
0.56	GO:0005813	centrosome
0.55	GO:0043197	dendritic spine
0.47	GO:0098857	membrane microdomain
0.47	GO:0031588	nucleotide-activated protein kinase complex
0.46	GO:0005930	axoneme
0.44	GO:0098590	plasma membrane region
0.39	GO:0043025	neuronal cell body

sp|P12371|FCERA_RAT
High affinity immunoglobulin epsilon receptor subunit alpha
Search

FCER1A

0.93	Fc of IgE, high affinity I, receptor for alpha polypeptide

0.47	GO:0002445	type II hypersensitivity
0.47	GO:0001812	positive regulation of type I hypersensitivity
0.47	GO:0001805	positive regulation of type III hypersensitivity
0.47	GO:0001798	positive regulation of type IIa hypersensitivity
0.46	GO:0001820	serotonin secretion
0.46	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
0.46	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.46	GO:0038094	Fc-gamma receptor signaling pathway
0.45	GO:0001909	leukocyte mediated cytotoxicity
0.45	GO:0045576	mast cell activation

0.47	GO:0019770	IgG receptor activity
0.46	GO:0019864	IgG binding
0.41	GO:0034987	immunoglobulin receptor binding

0.62	GO:0009986	cell surface
0.42	GO:0098552	side of membrane
0.39	GO:0070062	extracellular exosome
0.39	GO:0044459	plasma membrane part
0.30	GO:0016021	integral component of membrane

sp|P12389|ACHA2_RAT
Neuronal acetylcholine receptor subunit alpha-2
Search

CHRNA2

0.93	Nicotinic acetylcholine receptor alpha 2 subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0035094	response to nicotine
0.56	GO:0007271	synaptic transmission, cholinergic
0.52	GO:0007274	neuromuscular synaptic transmission
0.47	GO:0060080	inhibitory postsynaptic potential
0.46	GO:0014059	regulation of dopamine secretion
0.46	GO:0035640	exploration behavior
0.46	GO:0007585	respiratory gaseous exchange
0.46	GO:0051899	membrane depolarization

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.54	GO:0042166	acetylcholine binding
0.34	GO:0005515	protein binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.62	GO:0005892	acetylcholine-gated channel complex
0.44	GO:0009897	external side of plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite

sp|P12390|ACHB2_RAT
Neuronal acetylcholine receptor subunit beta-2
Search

CHRNB2

0.91	Neuronal nicotinic acetylcholine receptor beta 2 subunit

0.80	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.50	GO:0035094	response to nicotine
0.50	GO:0007274	neuromuscular synaptic transmission
0.49	GO:0060073	micturition
0.49	GO:0021771	lateral geniculate nucleus development
0.49	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep
0.48	GO:0033603	positive regulation of dopamine secretion
0.48	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep
0.48	GO:0001661	conditioned taste aversion

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.48	GO:0042166	acetylcholine binding
0.40	GO:0046982	protein heterodimerization activity

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.50	GO:0005892	acetylcholine-gated channel complex
0.45	GO:0009897	external side of plasma membrane
0.42	GO:0044853	plasma membrane raft
0.42	GO:0043204	perikaryon
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon
0.34	GO:0005737	cytoplasm

sp|P12391|ACHB3_RAT
Neuronal acetylcholine receptor subunit beta-3
Search

CHRNB3

0.93	Neuronal acetylcholine receptor subunit non-alpha-3

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.46	GO:0035094	response to nicotine
0.46	GO:0007271	synaptic transmission, cholinergic
0.45	GO:0007274	neuromuscular synaptic transmission
0.40	GO:0051291	protein heterooligomerization
0.38	GO:0006812	cation transport

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.46	GO:0042166	acetylcholine binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.45	GO:0005892	acetylcholine-gated channel complex
0.39	GO:0043005	neuron projection

sp|P12392|ACHB4_RAT
Neuronal acetylcholine receptor subunit beta-4
Search

CHRNB4

0.95	Neuronal acetylcholine receptor subunit beta-4

0.80	GO:0060079	excitatory postsynaptic potential
0.63	GO:0060084	synaptic transmission involved in micturition
0.61	GO:0035094	response to nicotine
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0006939	smooth muscle contraction
0.56	GO:0001508	action potential
0.55	GO:0030534	adult behavior
0.55	GO:0051971	positive regulation of transmission of nerve impulse
0.54	GO:0007626	locomotory behavior
0.52	GO:0006940	regulation of smooth muscle contraction

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.57	GO:0042166	acetylcholine binding
0.40	GO:0046982	protein heterodimerization activity

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.63	GO:0005892	acetylcholine-gated channel complex
0.43	GO:0009897	external side of plasma membrane
0.39	GO:0043005	neuron projection
0.36	GO:0098805	whole membrane
0.36	GO:0070820	tertiary granule
0.36	GO:0042581	specific granule
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0098588	bounding membrane of organelle

sp|P12526|MAS_RAT
Proto-oncogene Mas
Search

MAS1

0.94	MAS1 proto-oncogene, G protein-coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.69	GO:0070528	protein kinase C signaling
0.67	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.66	GO:1904385	cellular response to angiotensin
0.62	GO:0050727	regulation of inflammatory response
0.40	GO:0060732	positive regulation of inositol phosphate biosynthetic process
0.40	GO:0034698	response to gonadotropin
0.39	GO:0014823	response to activity
0.39	GO:0021766	hippocampus development
0.39	GO:0045740	positive regulation of DNA replication

0.72	GO:0004930	G-protein coupled receptor activity
0.61	GO:0042277	peptide binding
0.61	GO:0001653	peptide receptor activity
0.39	GO:0042562	hormone binding

0.47	GO:0005886	plasma membrane
0.40	GO:0005622	intracellular
0.37	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P12527|LOX5_RAT
Arachidonate 5-lipoxygenase
Search

ALOX5

0.97	Arachidonate 5-lipoxygenase a

0.61	GO:0019370	leukotriene biosynthetic process
0.59	GO:0002540	leukotriene production involved in inflammatory response
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0033559	unsaturated fatty acid metabolic process
0.39	GO:0019372	lipoxygenase pathway
0.38	GO:0001676	long-chain fatty acid metabolic process
0.36	GO:0035655	interleukin-18-mediated signaling pathway
0.36	GO:0055093	response to hyperoxia
0.36	GO:0045907	positive regulation of vasoconstriction
0.36	GO:0043312	neutrophil degranulation

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.38	GO:0004464	leukotriene-C4 synthase activity
0.38	GO:0008391	arachidonic acid monooxygenase activity
0.36	GO:0005515	protein binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0005509	calcium ion binding

0.60	GO:0005641	nuclear envelope lumen
0.58	GO:0016363	nuclear matrix
0.56	GO:0031965	nuclear membrane
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0005615	extracellular space
0.36	GO:0034774	secretory granule lumen
0.36	GO:0042383	sarcolemma
0.35	GO:0030425	dendrite

0.75	EC:1.13.11	GO:0016702
0.38	KEGG:R03059	GO:0004464

sp|P12711|ADHX_RAT
Alcohol dehydrogenase class-3
Search

ADH5

0.60	S-(hydroxymethyl)glutathione dehydrogenase

0.80	GO:0006069	ethanol oxidation
0.52	GO:0018119	peptidyl-cysteine S-nitrosylation
0.51	GO:0003016	respiratory system process
0.51	GO:0045777	positive regulation of blood pressure
0.50	GO:0051775	response to redox state
0.50	GO:0001523	retinoid metabolic process
0.49	GO:0051409	response to nitrosative stress
0.49	GO:0032496	response to lipopolysaccharide
0.48	GO:0046294	formaldehyde catabolic process
0.35	GO:0006068	ethanol catabolic process

0.80	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.62	GO:0008270	zinc ion binding
0.53	GO:0018467	formaldehyde dehydrogenase activity
0.52	GO:0005504	fatty acid binding
0.50	GO:0004022	alcohol dehydrogenase (NAD) activity
0.46	GO:0042803	protein homodimerization activity
0.33	GO:0009055	electron transfer activity

0.41	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80	EC:1.1.1.284	GO:0051903
0.80	KEGG:R06983 KEGG:R07140	GO:0051903

sp|P12749|RL26_RAT
60S ribosomal protein L26
Search

RPL26

0.79	Ribosomal protein L26, pseudogene 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.55	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.54	GO:1904803	regulation of translation involved in cellular response to UV
0.54	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.54	GO:0010467	gene expression
0.53	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0042273	ribosomal large subunit biogenesis
0.52	GO:0071480	cellular response to gamma radiation

0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.71	GO:0015934	large ribosomal subunit
0.52	GO:0022626	cytosolic ribosome
0.46	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0043195	terminal bouton
0.30	GO:0031224	intrinsic component of membrane

sp|P12760|NMU_RAT
Neuromedin-U
Search

NMU

0.95	Neuromedin U peptide

0.84	GO:0006940	regulation of smooth muscle contraction
0.67	GO:2000821	regulation of grooming behavior
0.64	GO:0097009	energy homeostasis
0.64	GO:0060259	regulation of feeding behavior
0.63	GO:0001659	temperature homeostasis
0.61	GO:0007218	neuropeptide signaling pathway
0.51	GO:0044495	modulation of blood pressure in other organism
0.51	GO:0120060	regulation of gastric emptying
0.51	GO:1902722	positive regulation of prolactin secretion
0.50	GO:1904058	positive regulation of sensory perception of pain

0.69	GO:0042922	neuromedin U receptor binding
0.35	GO:0005179	hormone activity

0.47	GO:0043195	terminal bouton
0.41	GO:0005576	extracellular region

sp|P12785|FAS_RAT
Fatty acid synthase
Search

FASN

0.73	Fatty acid synthase

0.56	GO:0071353	cellular response to interleukin-4
0.53	GO:0030879	mammary gland development
0.52	GO:0055114	oxidation-reduction process
0.49	GO:0006633	fatty acid biosynthetic process
0.38	GO:0001649	osteoblast differentiation
0.38	GO:0032100	positive regulation of appetite
0.38	GO:0006084	acetyl-CoA metabolic process
0.37	GO:0030223	neutrophil differentiation
0.37	GO:1903131	mononuclear cell differentiation
0.36	GO:0008611	ether lipid biosynthetic process

0.84	GO:0004317	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
0.84	GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity
0.83	GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity
0.83	GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity
0.83	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity
0.82	GO:0004319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
0.76	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity
0.74	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.74	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity
0.73	GO:0031177	phosphopantetheine binding

0.59	GO:0042587	glycogen granule
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.41	GO:0042470	melanosome
0.37	GO:0070062	extracellular exosome

0.84	EC:4.2.1.61	GO:0004317
0.84	KEGG:R04462	GO:0004317

sp|P12788|TRY4_RAT
Trypsin-4
Search

0.47	Pancreatic anionic trypsinogen

0.61	GO:0006508	proteolysis
0.51	GO:0007586	digestion
0.39	GO:0030574	collagen catabolic process
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.38	GO:0035094	response to nicotine
0.34	GO:0043542	endothelial cell migration
0.34	GO:0007596	blood coagulation
0.33	GO:0051604	protein maturation

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0005509	calcium ion binding
0.35	GO:0097655	serpin family protein binding
0.34	GO:0046982	protein heterodimerization activity

0.50	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0097180	serine protease inhibitor complex
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P12839|NFM_RAT
Neurofilament medium polypeptide
Search

NEFM

0.96	Neurofilament medium polypeptide

0.77	GO:0061564	axon development
0.48	GO:0060052	neurofilament cytoskeleton organization
0.44	GO:1990830	cellular response to leukemia inhibitory factor
0.41	GO:0045110	intermediate filament bundle assembly
0.40	GO:0031133	regulation of axon diameter
0.39	GO:0008088	axo-dendritic transport
0.38	GO:0045105	intermediate filament polymerization or depolymerization
0.38	GO:1903937	response to acrylamide
0.37	GO:0000226	microtubule cytoskeleton organization
0.37	GO:0007420	brain development

0.62	GO:0005198	structural molecule activity
0.36	GO:0015643	toxic substance binding
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0005102	receptor binding
0.34	GO:0008017	microtubule binding

0.85	GO:0005883	neurofilament
0.59	GO:0097418	neurofibrillary tangle
0.45	GO:0043209	myelin sheath
0.42	GO:0036464	cytoplasmic ribonucleoprotein granule
0.42	GO:0031965	nuclear membrane
0.40	GO:0005654	nucleoplasm
0.39	GO:0030424	axon
0.39	GO:0031594	neuromuscular junction
0.38	GO:0014069	postsynaptic density
0.36	GO:0043204	perikaryon

sp|P12841|FOS_RAT
Proto-oncogene c-Fos
Search

FOS

0.96	Proto-oncogene protein c-FOS

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0035994	response to muscle stretch
0.62	GO:0045672	positive regulation of osteoclast differentiation
0.60	GO:0071277	cellular response to calcium ion
0.60	GO:0035914	skeletal muscle cell differentiation
0.60	GO:0071276	cellular response to cadmium ion
0.60	GO:0060395	SMAD protein signal transduction
0.58	GO:0007179	transforming growth factor beta receptor signaling pathway
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0034614	cellular response to reactive oxygen species

0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0070412	R-SMAD binding
0.60	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.60	GO:0001102	RNA polymerase II activating transcription factor binding
0.59	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003682	chromatin binding
0.54	GO:0046982	protein heterodimerization activity
0.33	GO:0005198	structural molecule activity

0.74	GO:0005667	transcription factor complex
0.52	GO:0032993	protein-DNA complex
0.51	GO:0005654	nucleoplasm
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0005829	cytosol
0.39	GO:0043005	neuron projection
0.35	GO:0042025	host cell nucleus
0.33	GO:0019028	viral capsid
0.30	GO:0016020	membrane

sp|P12843|IBP2_RAT
Insulin-like growth factor-binding protein 2
Search

IGFBP2

0.96	Insulin like growth factor binding protein 2

0.71	GO:0001558	regulation of cell growth
0.59	GO:0042104	positive regulation of activated T cell proliferation
0.53	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.52	GO:0032868	response to insulin
0.42	GO:0032501	multicellular organismal process
0.42	GO:0010226	response to lithium ion
0.42	GO:0032502	developmental process
0.41	GO:0048640	negative regulation of developmental growth
0.41	GO:0032355	response to estradiol
0.41	GO:0043627	response to estrogen

0.83	GO:0005520	insulin-like growth factor binding
0.35	GO:0005102	receptor binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.66	GO:0005576	extracellular region
0.40	GO:0016324	apical plasma membrane
0.38	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

0.33

GO:0016746

sp|P12847|MYH3_RAT
Myosin-3
Search

0.83	Developmental myosin heavy chain embryonic

0.74	GO:0007018	microtubule-based movement
0.60	GO:0006936	muscle contraction
0.58	GO:0050881	musculoskeletal movement
0.52	GO:0033275	actin-myosin filament sliding
0.46	GO:0046034	ATP metabolic process
0.45	GO:0014823	response to activity
0.40	GO:0001778	plasma membrane repair
0.35	GO:0030036	actin cytoskeleton organization
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0060325	face morphogenesis

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.60	GO:0000146	microfilament motor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0016887	ATPase activity
0.44	GO:0005516	calmodulin binding
0.37	GO:0017018	myosin phosphatase activity

0.77	GO:0016459	myosin complex
0.58	GO:0043292	contractile fiber
0.45	GO:0014704	intercalated disc
0.41	GO:0036464	cytoplasmic ribonucleoprotein granule
0.39	GO:0005826	actomyosin contractile ring
0.37	GO:0005794	Golgi apparatus
0.36	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.45

GO:0016887

sp|P12928|KPYR_RAT
Pyruvate kinase PKLR
Search

PKLR

0.47	Pyruvate kinase PKLR

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.47	GO:0032869	cellular response to insulin stimulus
0.40	GO:0012501	programmed cell death
0.39	GO:0071872	cellular response to epinephrine stimulus
0.39	GO:0010226	response to lithium ion
0.39	GO:0051591	response to cAMP
0.38	GO:0033198	response to ATP

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.40	GO:0045296	cadherin binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005248	voltage-gated sodium channel activity
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity

0.41	GO:0005829	cytosol
0.41	GO:0043209	myelin sheath
0.39	GO:0005929	cilium
0.37	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:0005739	mitochondrion
0.33	GO:0005887	integral component of plasma membrane

0.78

EC:2.7.1.40

GO:0004743

sp|P12938|CP2D3_RAT
Cytochrome P450 2D3
Search

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0019369	arachidonic acid metabolic process
0.39	GO:0007565	female pregnancy
0.38	GO:0090349	negative regulation of cellular organohalogen metabolic process
0.38	GO:0090348	regulation of cellular organofluorine metabolic process
0.37	GO:0009822	alkaloid catabolic process
0.37	GO:0033076	isoquinoline alkaloid metabolic process
0.37	GO:0006587	serotonin biosynthetic process from tryptophan
0.37	GO:0009804	coumarin metabolic process
0.37	GO:0016098	monoterpenoid metabolic process

0.80	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.50	GO:0008395	steroid hydroxylase activity
0.37	GO:0008391	arachidonic acid monooxygenase activity
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.80

GO:0016712

sp|P12939|CP2DA_RAT
Cytochrome P450 2D10
Search

0.97	Cytochrome P450, family 2, subfamily d, polypeptide 5

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0019369	arachidonic acid metabolic process
0.38	GO:0007565	female pregnancy
0.38	GO:0090349	negative regulation of cellular organohalogen metabolic process
0.38	GO:0090348	regulation of cellular organofluorine metabolic process
0.37	GO:0042738	exogenous drug catabolic process
0.37	GO:0009822	alkaloid catabolic process
0.37	GO:0033076	isoquinoline alkaloid metabolic process
0.37	GO:0006587	serotonin biosynthetic process from tryptophan
0.37	GO:0009804	coumarin metabolic process

0.80	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.50	GO:0008395	steroid hydroxylase activity
0.37	GO:0008391	arachidonic acid monooxygenase activity
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0016712

sp|P12969|IAPP_RAT
Islet amyloid polypeptide
Search

IAPP

0.95	islet amyloid polypeptide precursor

0.76	GO:0010469	regulation of receptor activity
0.66	GO:0045779	negative regulation of bone resorption
0.63	GO:0019233	sensory perception of pain
0.59	GO:0045596	negative regulation of cell differentiation
0.47	GO:0097647	amylin receptor signaling pathway
0.46	GO:0042755	eating behavior
0.41	GO:0030816	positive regulation of cAMP metabolic process
0.39	GO:0031018	endocrine pancreas development
0.38	GO:1905907	negative regulation of amyloid fibril formation
0.38	GO:1900019	regulation of protein kinase C activity

0.79	GO:0005179	hormone activity
0.55	GO:0042802	identical protein binding
0.37	GO:0001540	amyloid-beta binding

0.66	GO:0005576	extracellular region
0.60	GO:0043025	neuronal cell body
0.38	GO:0030141	secretory granule
0.37	GO:0016234	inclusion body
0.36	GO:0005829	cytosol

sp|P13053|VDR_RAT
Vitamin D3 receptor
Search

VDR

0.97	Vitamin D receptor

0.86	GO:0070561	vitamin D receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0038183	bile acid signaling pathway
0.57	GO:0010980	positive regulation of vitamin D 24-hydroxylase activity
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0045618	positive regulation of keratinocyte differentiation
0.56	GO:0010839	negative regulation of keratinocyte proliferation

0.87	GO:0008434	calcitriol receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.59	GO:1902098	calcitriol binding
0.59	GO:1902121	lithocholic acid binding
0.58	GO:0038186	lithocholic acid receptor activity
0.56	GO:0046965	retinoid X receptor binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0043235	receptor complex
0.49	GO:0005667	transcription factor complex
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.37	GO:0005901	caveola
0.35	GO:0030315	T-tubule
0.35	GO:0005737	cytoplasm
0.34	GO:0005694	chromosome

sp|P13084|NPM_RAT
Nucleophosmin
Search

NPM1

0.93	Nucleophosmin

0.51	GO:0060735	regulation of eIF2 alpha phosphorylation by dsRNA
0.49	GO:0010824	regulation of centrosome duplication
0.49	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.48	GO:0032071	regulation of endodeoxyribonuclease activity
0.48	GO:1904751	positive regulation of protein localization to nucleolus
0.47	GO:0090068	positive regulation of cell cycle process
0.47	GO:0007569	cell aging
0.47	GO:0007098	centrosome cycle
0.47	GO:0008284	positive regulation of cell proliferation
0.47	GO:0060699	regulation of endoribonuclease activity

0.50	GO:0003676	nucleic acid binding
0.49	GO:0051059	NF-kappaB binding
0.48	GO:0030957	Tat protein binding
0.47	GO:0043024	ribosomal small subunit binding
0.46	GO:0001105	RNA polymerase II transcription coactivator activity
0.46	GO:0004860	protein kinase inhibitor activity
0.46	GO:0033613	activating transcription factor binding
0.45	GO:0047485	protein N-terminus binding
0.45	GO:0019901	protein kinase binding
0.45	GO:0042393	histone binding

0.47	GO:0031616	spindle pole centrosome
0.47	GO:0001652	granular component
0.44	GO:0005654	nucleoplasm
0.42	GO:0032993	protein-DNA complex
0.41	GO:0005829	cytosol
0.41	GO:0015934	large ribosomal subunit
0.41	GO:0015935	small ribosomal subunit
0.39	GO:0016363	nuclear matrix
0.39	GO:0043234	protein complex
0.37	GO:0005925	focal adhesion

sp|P13085|PTHR_RAT
Parathyroid hormone-related protein
Search

PTHLH

0.97	Parathyroid hormone like hormone

0.85	GO:0032330	regulation of chondrocyte differentiation
0.75	GO:0010469	regulation of receptor activity
0.61	GO:0061037	negative regulation of cartilage development
0.60	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.60	GO:0030819	positive regulation of cAMP biosynthetic process
0.56	GO:0045596	negative regulation of cell differentiation
0.56	GO:0001501	skeletal system development
0.52	GO:0002076	osteoblast development
0.44	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0042127	regulation of cell proliferation

0.79	GO:0005179	hormone activity
0.64	GO:0051428	peptide hormone receptor binding

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol

sp|P13086|SUCA_RAT
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
Search

SUCLG1

0.88	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

0.65	GO:0006099	tricarboxylic acid cycle
0.35	GO:0006104	succinyl-CoA metabolic process
0.34	GO:0006105	succinate metabolic process

0.80	GO:0004776	succinate-CoA ligase (GDP-forming) activity
0.71	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.54	GO:0048037	cofactor binding
0.49	GO:1901265	nucleoside phosphate binding
0.48	GO:0036094	small molecule binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0003723	RNA binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0043168	anion binding

0.56	GO:0005739	mitochondrion
0.45	GO:0005829	cytosol
0.42	GO:0019866	organelle inner membrane
0.41	GO:0031974	membrane-enclosed lumen
0.40	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0042709	succinate-CoA ligase complex

0.80	EC:6.2.1.4	GO:0004776
0.80	KEGG:R00432	GO:0004776

sp|P13107|CP2B3_RAT
Cytochrome P450 2B3
Search

CYP2B

0.97	Testosterone 16a-hydroxylase type b

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0019373	epoxygenase P450 pathway
0.47	GO:0042738	exogenous drug catabolic process
0.44	GO:0006805	xenobiotic metabolic process
0.43	GO:0008202	steroid metabolic process
0.42	GO:0042180	cellular ketone metabolic process
0.38	GO:0014070	response to organic cyclic compound
0.37	GO:0051592	response to calcium ion
0.36	GO:0010477	response to sulfur dioxide
0.36	GO:0018933	nicotine metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.52	GO:0008392	arachidonic acid epoxygenase activity
0.51	GO:0008395	steroid hydroxylase activity
0.38	GO:0019825	oxygen binding
0.34	GO:0004721	phosphoprotein phosphatase activity

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P13108|CP2D4_RAT
Cytochrome P450 2D4
Search

CYP2D6

0.97	Cytochrome P450, family 2, subfamily D, polypeptide 6

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0019369	arachidonic acid metabolic process
0.39	GO:0007565	female pregnancy
0.38	GO:0090349	negative regulation of cellular organohalogen metabolic process
0.38	GO:0090348	regulation of cellular organofluorine metabolic process
0.38	GO:0042738	exogenous drug catabolic process
0.38	GO:0006587	serotonin biosynthetic process from tryptophan
0.38	GO:0009822	alkaloid catabolic process
0.38	GO:0033076	isoquinoline alkaloid metabolic process
0.38	GO:0009804	coumarin metabolic process

0.80	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.49	GO:0008395	steroid hydroxylase activity
0.37	GO:0008391	arachidonic acid monooxygenase activity
0.34	GO:0019825	oxygen binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0016712

sp|P13109|FGF2_RAT
Fibroblast growth factor 2
Search

FGF2

0.61	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.64	GO:0001525	angiogenesis
0.61	GO:0051781	positive regulation of cell division
0.58	GO:0045766	positive regulation of angiogenesis
0.57	GO:0030154	cell differentiation
0.57	GO:0001759	organ induction
0.57	GO:0010595	positive regulation of endothelial cell migration
0.55	GO:0042127	regulation of cell proliferation
0.55	GO:0035295	tube development

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.61	GO:0008201	heparin binding
0.50	GO:0044548	S100 protein binding
0.49	GO:0005178	integrin binding
0.39	GO:0090722	receptor-receptor interaction
0.38	GO:0042056	chemoattractant activity
0.38	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.37	GO:0005125	cytokine activity
0.37	GO:0030544	Hsp70 protein binding

0.66	GO:0005576	extracellular region
0.54	GO:0005938	cell cortex
0.50	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P13195|HEM1_RAT
5-aminolevulinate synthase, nonspecific, mitochondrial
Search

ALAS1

0.63	5-aminolevulinate synthase, nonspecific, mitochondrial

0.71	GO:0006782	protoporphyrinogen IX biosynthetic process
0.36	GO:0070541	response to platinum ion
0.36	GO:0032025	response to cobalt ion
0.35	GO:0034698	response to gonadotropin
0.35	GO:0051591	response to cAMP
0.35	GO:0045471	response to ethanol
0.35	GO:0010045	response to nickel cation
0.35	GO:0032869	cellular response to insulin stimulus
0.35	GO:0009635	response to herbicide
0.35	GO:0001666	response to hypoxia

0.84	GO:0003870	5-aminolevulinate synthase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.50	GO:0042802	identical protein binding
0.34	GO:0016874	ligase activity

0.74	GO:0005759	mitochondrial matrix
0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

0.84	EC:2.3.1.37	GO:0003870
0.84	KEGG:R00830	GO:0003870

sp|P13205|ANFB_RAT
Natriuretic peptides B
Search

NPPB

0.92	Brain natriuretic peptide

0.79	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.61	GO:0007168	receptor guanylyl cyclase signaling pathway
0.60	GO:0003299	muscle hypertrophy in response to stress
0.60	GO:0014887	cardiac muscle adaptation
0.60	GO:0003300	cardiac muscle hypertrophy
0.57	GO:0006182	cGMP biosynthetic process
0.53	GO:1903816	positive regulation of collecting lymphatic vessel constriction
0.50	GO:0003298	physiological muscle hypertrophy
0.50	GO:0035815	positive regulation of renal sodium excretion

0.79	GO:0005179	hormone activity
0.53	GO:0051427	hormone receptor binding
0.39	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0043234	protein complex
0.40	GO:0005634	nucleus

sp|P13207|EDN3_RAT
Endothelin-3
Search

EDN3

0.88	Endothelin A

0.85	GO:0019229	regulation of vasoconstriction
0.51	GO:0014033	neural crest cell differentiation
0.50	GO:0014031	mesenchymal cell development
0.50	GO:0048864	stem cell development
0.49	GO:0006874	cellular calcium ion homeostasis
0.49	GO:0014826	vein smooth muscle contraction
0.49	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.48	GO:0008284	positive regulation of cell proliferation
0.48	GO:0030334	regulation of cell migration
0.48	GO:0051050	positive regulation of transport

0.49	GO:0031708	endothelin B receptor binding
0.46	GO:0031707	endothelin A receptor binding
0.45	GO:0005179	hormone activity
0.42	GO:0005125	cytokine activity
0.35	GO:0004459	L-lactate dehydrogenase activity
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.35	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.35

EC:1.1.1.27

GO:0004459

sp|P13221|AATC_RAT
Aspartate aminotransferase, cytoplasmic
Search

GOT1

0.49	Aspartate aminotransferase

0.61	GO:0006114	glycerol biosynthetic process
0.61	GO:0006532	aspartate biosynthetic process
0.61	GO:0019550	glutamate catabolic process to aspartate
0.60	GO:0006533	aspartate catabolic process
0.59	GO:0055089	fatty acid homeostasis
0.57	GO:0051384	response to glucocorticoid
0.56	GO:0032869	cellular response to insulin stimulus
0.56	GO:0006103	2-oxoglutarate metabolic process
0.55	GO:0007219	Notch signaling pathway
0.55	GO:0006107	oxaloacetate metabolic process

0.81	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.78	GO:0070546	L-phenylalanine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.54	GO:0004609	phosphatidylserine decarboxylase activity
0.48	GO:0047801	L-cysteine:2-oxoglutarate aminotransferase activity
0.37	GO:0031406	carboxylic acid binding

0.50	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.40	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome

0.81	EC:2.6.1.1	GO:0004069
0.81	KEGG:R00355	GO:0004069

sp|P13233|CN37_RAT
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Search

CNP

0.95	2',3'-cyclic-nucleotide 3'-phosphodiesterase

0.84	GO:0009214	cyclic nucleotide catabolic process
0.59	GO:0048709	oligodendrocyte differentiation
0.58	GO:0008344	adult locomotory behavior
0.56	GO:0061564	axon development
0.55	GO:0048667	cell morphogenesis involved in neuron differentiation
0.55	GO:0048812	neuron projection morphogenesis
0.49	GO:0009636	response to toxic substance
0.41	GO:0046902	regulation of mitochondrial membrane permeability
0.41	GO:0032496	response to lipopolysaccharide
0.41	GO:0000226	microtubule cytoskeleton organization

0.81	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
0.49	GO:0003723	RNA binding
0.40	GO:0030551	cyclic nucleotide binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005525	GTP binding
0.34	GO:0016301	kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.65	GO:0042470	melanosome
0.57	GO:0043209	myelin sheath
0.52	GO:0005615	extracellular space
0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.42	GO:0031143	pseudopodium
0.41	GO:0005902	microvillus
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005741	mitochondrial outer membrane
0.39	GO:0005874	microtubule

0.81

EC:3.1.4.37

GO:0004113

sp|P13234|KCC4_RAT
Calcium/calmodulin-dependent protein kinase type IV
Search

CAMK4

0.95	LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type IV

0.63	GO:0006468	protein phosphorylation
0.56	GO:0043011	myeloid dendritic cell differentiation
0.55	GO:0007616	long-term memory
0.51	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0018209	peptidyl-serine modification
0.42	GO:0035556	intracellular signal transduction
0.40	GO:0002372	myeloid dendritic cell cytokine production
0.40	GO:0060216	definitive hemopoiesis
0.39	GO:0002250	adaptive immune response
0.39	GO:0006954	inflammatory response

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005516	calmodulin binding
0.35	GO:0046875	ephrin receptor binding
0.34	GO:0048038	quinone binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0046872	metal ion binding

0.53	GO:0001650	fibrillar center
0.47	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.33

GO:0008137

sp|P13255|GNMT_RAT
Glycine N-methyltransferase
Search

GNMT

0.97	Glycine N-methyltransferase

0.63	GO:0032259	methylation
0.56	GO:0051289	protein homotetramerization
0.55	GO:0006111	regulation of gluconeogenesis
0.55	GO:0046500	S-adenosylmethionine metabolic process
0.52	GO:0006555	methionine metabolic process
0.51	GO:0005977	glycogen metabolic process
0.50	GO:0006730	one-carbon metabolic process
0.46	GO:1901052	sarcosine metabolic process
0.43	GO:0070328	triglyceride homeostasis
0.42	GO:0008340	determination of adult lifespan

0.85	GO:0017174	glycine N-methyltransferase activity
0.59	GO:0016594	glycine binding
0.50	GO:0042802	identical protein binding
0.41	GO:0052729	dimethylglycine N-methyltransferase activity
0.40	GO:0052730	sarcosine N-methyltransferase activity
0.40	GO:0005542	folic acid binding
0.37	GO:0098603	selenol Se-methyltransferase activity
0.35	GO:1904047	S-adenosyl-L-methionine binding
0.33	GO:0030145	manganese ion binding
0.32	GO:0003723	RNA binding

0.48	GO:0005829	cytosol
0.34	GO:0034708	methyltransferase complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85	EC:2.1.1.156 EC:2.1.1.162 EC:2.1.1.20	GO:0017174
0.85	KEGG:R00367	GO:0017174

sp|P13264|GLSK_RAT
Glutaminase kidney isoform, mitochondrial
Search

GLS

0.49	Glutaminase kidney

0.71	GO:0006541	glutamine metabolic process
0.56	GO:0001967	suckling behavior
0.56	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.53	GO:0051289	protein homotetramerization
0.52	GO:0006537	glutamate biosynthetic process
0.51	GO:0009065	glutamine family amino acid catabolic process
0.50	GO:0007268	chemical synaptic transmission
0.36	GO:0014047	glutamate secretion

0.79	GO:0004359	glutaminase activity
0.36	GO:0042802	identical protein binding

0.45	GO:0005759	mitochondrial matrix
0.36	GO:0005829	cytosol

0.79

EC:3.5.1.2

GO:0004359

sp|P13265|GPC3_RAT
Glypican-3
Search

GPC3

0.96	Intestinal protein OCI-5 (Fragment)

0.70	GO:0009966	regulation of signal transduction
0.61	GO:0061209	cell proliferation involved in mesonephros development
0.61	GO:0072180	mesonephric duct morphogenesis
0.61	GO:0072203	cell proliferation involved in metanephros development
0.59	GO:0010463	mesenchymal cell proliferation
0.59	GO:0035116	embryonic hindlimb morphogenesis
0.58	GO:0030282	bone mineralization
0.58	GO:0030316	osteoclast differentiation
0.58	GO:0046326	positive regulation of glucose import
0.58	GO:0060976	coronary vasculature development

0.83	GO:0043395	heparan sulfate proteoglycan binding
0.63	GO:0060422	peptidyl-dipeptidase inhibitor activity
0.32	GO:0003735	structural constituent of ribosome

0.83	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix
0.54	GO:0005764	lysosome
0.40	GO:0005796	Golgi lumen
0.39	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.36	GO:0005775	vacuolar lumen
0.36	GO:0005887	integral component of plasma membrane
0.36	GO:0005788	endoplasmic reticulum lumen
0.32	GO:0005840	ribosome

sp|P13286|PHKG1_RAT
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
Search

PHKG1

0.97	Phosphorylase kinase catalytic subunit gamma 1

0.76	GO:0005978	glycogen biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.49	GO:0018210	peptidyl-threonine modification
0.48	GO:0018209	peptidyl-serine modification
0.42	GO:0035556	intracellular signal transduction
0.39	GO:0001525	angiogenesis
0.34	GO:0005980	glycogen catabolic process

0.86	GO:0004689	phosphorylase kinase activity
0.79	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0050321	tau-protein kinase activity
0.36	GO:0019899	enzyme binding

0.85	GO:0005964	phosphorylase kinase complex
0.36	GO:0005829	cytosol
0.36	GO:0098723	skeletal muscle myofibril
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.7.11.19

GO:0004689

sp|P13383|NUCL_RAT
Nucleolin
Search

NCL

0.87

Nucleolin

0.56	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.55	GO:0071364	cellular response to epidermal growth factor stimulus
0.54	GO:1990830	cellular response to leukemia inhibitory factor
0.52	GO:0072359	circulatory system development
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0017148	negative regulation of translation
0.49	GO:0009653	anatomical structure morphogenesis
0.42	GO:0009303	rRNA transcription
0.41	GO:0007368	determination of left/right symmetry
0.40	GO:0048513	animal organ development

0.59	GO:0003723	RNA binding
0.56	GO:0044547	DNA topoisomerase binding
0.53	GO:0042162	telomeric DNA binding
0.52	GO:0008022	protein C-terminus binding
0.48	GO:0042802	identical protein binding
0.39	GO:1990631	ErbB-4 class receptor binding
0.37	GO:0043236	laminin binding
0.36	GO:0042393	histone binding
0.35	GO:0003697	single-stranded DNA binding
0.35	GO:0005509	calcium ion binding

0.50	GO:0036464	cytoplasmic ribonucleoprotein granule
0.50	GO:0005730	nucleolus
0.49	GO:0005938	cell cortex
0.47	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.32	EC:2.8.3.16	GO:0033608
0.32	KEGG:R07290	GO:0033608

sp|P13386|FCERB_RAT
High affinity immunoglobulin epsilon receptor subunit beta
Search

MS4A2

0.97	Membrane spanning 4-domains A2

0.86	GO:0038095	Fc-epsilon receptor signaling pathway
0.80	GO:0006954	inflammatory response
0.70	GO:0006955	immune response

0.85

GO:0019863

IgE binding

0.87	GO:0032997	Fc receptor complex
0.77	GO:0009897	external side of plasma membrane
0.67	GO:0005887	integral component of plasma membrane

sp|P13413|TNNI1_RAT
Troponin I, slow skeletal muscle
Search

TNNI1

0.92	Slow skeletal troponin I

0.55	GO:0014883	transition between fast and slow fiber
0.53	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.46	GO:0003009	skeletal muscle contraction
0.46	GO:0060048	cardiac muscle contraction
0.36	GO:0006937	regulation of muscle contraction
0.36	GO:0030049	muscle filament sliding
0.35	GO:1901876	regulation of calcium ion binding

0.37	GO:0003779	actin binding
0.34	GO:0046872	metal ion binding

0.83	GO:0005861	troponin complex
0.34	GO:0005829	cytosol

sp|P13432|SMR1_RAT
SMR1 protein
Search

0.15	Submaxillary gland androgen-regulated protein 3B

0.86	GO:0051930	regulation of sensory perception of pain
0.84	GO:0071222	cellular response to lipopolysaccharide
0.76	GO:0010951	negative regulation of endopeptidase activity
0.75	GO:0010469	regulation of receptor activity

0.79	GO:0005179	hormone activity
0.77	GO:0004866	endopeptidase inhibitor activity

0.81

GO:0070062

extracellular exosome

sp|P13437|THIM_RAT
3-ketoacyl-CoA thiolase, mitochondrial
Search

ACAA2

0.48	Acetyl-Coenzyme A acyltransferase 2

0.57	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process
0.57	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.53	GO:0071456	cellular response to hypoxia
0.45	GO:0006635	fatty acid beta-oxidation
0.35	GO:0006695	cholesterol biosynthetic process
0.34	GO:0006084	acetyl-CoA metabolic process
0.34	GO:0007018	microtubule-based movement

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.35	GO:0003779	actin binding
0.35	GO:0003774	motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0016459	myosin complex
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:2.3.1

GO:0016747

sp|P13444|METK1_RAT
S-adenosylmethionine synthase isoform type-1
Search

MAT1A

0.54	S-adenosylmethionine synthase

0.78	GO:0006556	S-adenosylmethionine biosynthetic process
0.72	GO:0006730	one-carbon metabolic process
0.59	GO:0009087	methionine catabolic process
0.55	GO:0051259	protein oligomerization
0.50	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:0055013	cardiac muscle cell development
0.39	GO:0072358	cardiovascular system development
0.34	GO:0001887	selenium compound metabolic process
0.34	GO:0032259	methylation

0.79	GO:0004478	methionine adenosyltransferase activity
0.55	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.36	GO:0098601	selenomethionine adenosyltransferase activity
0.34	GO:0016597	amino acid binding
0.33	GO:0046983	protein dimerization activity

0.55	GO:0048269	methionine adenosyltransferase complex
0.45	GO:0005829	cytosol
0.35	GO:0016363	nuclear matrix

0.79

EC:2.5.1.6

GO:0004478

sp|P13471|RS14_RAT
40S ribosomal protein S14
Search

RPS14

0.62	Ribosomal protein S14

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.54	GO:0030218	erythrocyte differentiation
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0000028	ribosomal small subunit assembly
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0006417	regulation of translation
0.44	GO:0061515	myeloid cell development
0.43	GO:0071695	anatomical structure maturation

0.64	GO:0003735	structural constituent of ribosome
0.51	GO:0048027	mRNA 5'-UTR binding
0.49	GO:0045182	translation regulator activity
0.44	GO:0070181	small ribosomal subunit rRNA binding
0.39	GO:0042289	MHC class II protein binding
0.34	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0005516	calmodulin binding
0.34	GO:0008146	sulfotransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.45	GO:0005730	nucleolus
0.40	GO:0005739	mitochondrion
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.11.17

GO:0004683

sp|P13589|PACA_RAT
Pituitary adenylate cyclase-activating polypeptide
Search

ADCYAP1

0.94	Pituitary adenylate cyclase-activating polypeptide

0.75	GO:0010469	regulation of receptor activity
0.60	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.59	GO:0007218	neuropeptide signaling pathway
0.57	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.57	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.57	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.54	GO:0007399	nervous system development
0.54	GO:0045860	positive regulation of protein kinase activity
0.53	GO:0120036	plasma membrane bounded cell projection organization
0.53	GO:0043547	positive regulation of GTPase activity

0.79	GO:0005179	hormone activity
0.60	GO:0051428	peptide hormone receptor binding
0.44	GO:0005057	signal transducer activity, downstream of receptor
0.44	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding

0.66	GO:0005576	extracellular region
0.41	GO:0043195	terminal bouton
0.38	GO:0005622	intracellular
0.37	GO:0070852	cell body fiber
0.36	GO:0043204	perikaryon
0.30	GO:0031224	intrinsic component of membrane

sp|P13596|NCAM1_RAT
Neural cell adhesion molecule 1
Search

NCAM1

0.91	Neural cell adhesion molecule 1

0.71	GO:0007155	cell adhesion
0.38	GO:0001928	regulation of exocyst assembly
0.37	GO:0031175	neuron projection development
0.37	GO:0050850	positive regulation of calcium-mediated signaling
0.36	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0010288	response to lead ion
0.35	GO:0021794	thalamus development
0.35	GO:0051930	regulation of sensory perception of pain
0.35	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.35	GO:0042220	response to cocaine

0.37	GO:0042802	identical protein binding
0.36	GO:0008201	heparin binding
0.35	GO:0030275	LRR domain binding
0.35	GO:0104005	hijacked molecular function
0.35	GO:0019899	enzyme binding
0.35	GO:0005104	fibroblast growth factor receptor binding
0.34	GO:0008092	cytoskeletal protein binding
0.34	GO:0098772	molecular function regulator

0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0009986	cell surface
0.37	GO:0098552	side of membrane
0.37	GO:0030426	growth cone
0.37	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.36	GO:0043025	neuronal cell body
0.36	GO:0030424	axon

sp|P13599|FCGRN_RAT
IgG receptor FcRn large subunit p51
Search

FCGRT

0.97	Neonatal Fc receptor FcRn alpha chain

0.55	GO:0038094	Fc-gamma receptor signaling pathway
0.39	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor
0.38	GO:0006959	humoral immune response
0.33	GO:0019882	antigen processing and presentation

0.67	GO:0019864	IgG binding
0.57	GO:0019770	IgG receptor activity
0.57	GO:0030881	beta-2-microglobulin binding
0.45	GO:0042605	peptide antigen binding
0.37	GO:0005509	calcium ion binding

0.42	GO:0005886	plasma membrane
0.32	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P13601|AL1A7_RAT
Aldehyde dehydrogenase, cytosolic 1
Search

ALDH1A1

0.79	Retinal dehydrogenase 1

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0042572	retinol metabolic process
0.43	GO:0042904	9-cis-retinoic acid biosynthetic process
0.43	GO:0002072	optic cup morphogenesis involved in camera-type eye development
0.40	GO:0043065	positive regulation of apoptotic process
0.39	GO:0042493	response to drug
0.38	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
0.38	GO:0044849	estrous cycle
0.38	GO:0007494	midgut development
0.37	GO:0032355	response to estradiol

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.41	GO:0051287	NAD binding
0.38	GO:0005497	androgen binding
0.36	GO:0005096	GTPase activator activity
0.36	GO:0042802	identical protein binding

0.47	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.69

EC:1.2.1

GO:0016620

sp|P13635|CERU_RAT
Ceruloplasmin
Search

0.69	Hephaestin-like protein 1

0.78	GO:0006825	copper ion transport
0.76	GO:0006879	cellular iron ion homeostasis
0.53	GO:0055114	oxidation-reduction process

0.81	GO:0004322	ferroxidase activity
0.72	GO:0005507	copper ion binding

0.30

GO:0005623

cell

0.81

EC:1.16.3.1

GO:0004322

sp|P13638|AT1B2_RAT
Sodium/potassium-transporting ATPase subunit beta-2
Search

ATP1B2

0.78	Sodium/potassium-transporting ATPase subunit beta

0.72	GO:0006814	sodium ion transport
0.70	GO:0006813	potassium ion transport
0.65	GO:1903288	positive regulation of potassium ion import
0.65	GO:1903278	positive regulation of sodium ion export across plasma membrane
0.63	GO:0006883	cellular sodium ion homeostasis
0.63	GO:0086009	membrane repolarization
0.62	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.61	GO:0030007	cellular potassium ion homeostasis
0.60	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.60	GO:0140115	export across plasma membrane

0.61	GO:0051117	ATPase binding
0.60	GO:0005391	sodium:potassium-exchanging ATPase activity
0.59	GO:0001671	ATPase activator activity

0.83	GO:0005890	sodium:potassium-exchanging ATPase complex
0.56	GO:0016324	apical plasma membrane
0.40	GO:0005737	cytoplasm
0.35	GO:0005901	caveola
0.35	GO:0097708	intracellular vesicle
0.35	GO:0070062	extracellular exosome

0.60

GO:0005391

sp|P13668|STMN1_RAT
Stathmin
Search

STMN1

0.86

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.55	GO:0007019	microtubule depolymerization
0.55	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.55	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.54	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.53	GO:0051497	negative regulation of stress fiber assembly
0.53	GO:0061436	establishment of skin barrier
0.53	GO:0035024	negative regulation of Rho protein signal transduction
0.52	GO:0032272	negative regulation of protein polymerization
0.51	GO:0031175	neuron projection development

0.49	GO:0015631	tubulin binding
0.38	GO:0048306	calcium-dependent protein binding
0.37	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.33	GO:0004871	signal transducer activity

0.46	GO:0043005	neuron projection
0.45	GO:0005829	cytosol
0.40	GO:0005874	microtubule
0.37	GO:0030027	lamellipodium
0.37	GO:0043025	neuronal cell body
0.37	GO:0030427	site of polarized growth
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.1.1.47

GO:0003847

sp|P13676|ACPH_RAT
Acylamino-acid-releasing enzyme
Search

APEH

0.81	N-acylaminoacyl-peptide hydrolase

0.60	GO:0006508	proteolysis
0.59	GO:0050435	amyloid-beta metabolic process
0.38	GO:0007416	synapse assembly
0.36	GO:0043312	neutrophil degranulation
0.34	GO:0006415	translational termination

0.66	GO:0017171	serine hydrolase activity
0.61	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.51	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.54	GO:0031965	nuclear membrane
0.49	GO:0005829	cytosol
0.38	GO:0048786	presynaptic active zone
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen

sp|P13697|MAOX_RAT
NADP-dependent malic enzyme
Search

ME1

0.53	NADP-dependent malic enzyme

0.58	GO:1902031	regulation of NADP metabolic process
0.56	GO:0006108	malate metabolic process
0.53	GO:0051262	protein tetramerization
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0006090	pyruvate metabolic process
0.38	GO:0009725	response to hormone
0.35	GO:0072592	oxygen metabolic process
0.35	GO:0009743	response to carbohydrate
0.34	GO:0019216	regulation of lipid metabolic process
0.34	GO:0006741	NADP biosynthetic process

0.78	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity
0.67	GO:0051287	NAD binding
0.59	GO:0004473	malate dehydrogenase (decarboxylating) (NADP+) activity
0.53	GO:0046872	metal ion binding
0.41	GO:0008948	oxaloacetate decarboxylase activity
0.35	GO:0050661	NADP binding
0.34	GO:0043531	ADP binding
0.33	GO:0005515	protein binding
0.33	GO:0009055	electron transfer activity

0.47	GO:0005739	mitochondrion
0.37	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.1.1.38 EC:1.1.1.39	GO:0004471
0.78	KEGG:R00214	GO:0004471

sp|P13721|SIAT1_RAT
Beta-galactoside alpha-2,6-sialyltransferase 1
Search

ST6GAL1

0.97	Beta-galactoside alpha-2,6-sialyltransferase

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.58	GO:0018196	peptidyl-asparagine modification
0.54	GO:0006054	N-acetylneuraminate metabolic process
0.47	GO:0009311	oligosaccharide metabolic process
0.37	GO:2000110	negative regulation of macrophage apoptotic process
0.36	GO:0050922	negative regulation of chemotaxis
0.36	GO:1900024	regulation of substrate adhesion-dependent cell spreading
0.36	GO:0045471	response to ethanol
0.36	GO:0032946	positive regulation of mononuclear cell proliferation

0.83	GO:0008373	sialyltransferase activity
0.33	GO:0005515	protein binding

0.65	GO:0005794	Golgi apparatus
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.37	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.83

EC:2.4.99

GO:0008373

sp|P13803|ETFA_RAT
Electron transfer flavoprotein subunit alpha, mitochondrial
Search

ETFA

0.65	Electron transferring flavoprotein, alpha polypeptide

0.61	GO:0022900	electron transport chain
0.46	GO:0031998	regulation of fatty acid beta-oxidation
0.46	GO:0070584	mitochondrion morphogenesis
0.43	GO:0009887	animal organ morphogenesis

0.66	GO:0050660	flavin adenine dinucleotide binding
0.62	GO:0009055	electron transfer activity

0.39

GO:0005739

mitochondrion

sp|P13832|MRLCA_RAT
Myosin regulatory light chain RLC-A
Search

0.87	Myosin regulatory light chain RLC-A

0.47	GO:0072659	protein localization to plasma membrane
0.43	GO:0008360	regulation of cell shape
0.36	GO:0031032	actomyosin structure organization
0.35	GO:0045652	regulation of megakaryocyte differentiation
0.34	GO:0070527	platelet aggregation
0.34	GO:0055002	striated muscle cell development
0.34	GO:0006937	regulation of muscle contraction
0.34	GO:0006936	muscle contraction
0.34	GO:0010927	cellular component assembly involved in morphogenesis
0.33	GO:0097435	supramolecular fiber organization

0.70	GO:0005509	calcium ion binding
0.49	GO:0035254	glutamate receptor binding
0.44	GO:0032036	myosin heavy chain binding
0.36	GO:0008307	structural constituent of muscle
0.35	GO:0045159	myosin II binding
0.35	GO:0030898	actin-dependent ATPase activity
0.34	GO:0051015	actin filament binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0032550	purine ribonucleoside binding

0.53	GO:0016460	myosin II complex
0.51	GO:0097517	contractile actin filament bundle
0.51	GO:0042641	actomyosin
0.51	GO:0030018	Z disc
0.39	GO:0099738	cell cortex region
0.35	GO:0097513	myosin II filament
0.34	GO:0005903	brush border
0.34	GO:0045177	apical part of cell
0.34	GO:0045202	synapse
0.33	GO:0005829	cytosol

sp|P13838|LEUK_RAT
Leukosialin (Fragment)
Search

SPN

0.97	Leukosialin

0.63	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.62	GO:0002296	T-helper 1 cell lineage commitment
0.60	GO:0032609	interferon-gamma production
0.55	GO:0042742	defense response to bacterium
0.55	GO:0001808	negative regulation of type IV hypersensitivity
0.54	GO:0050901	leukocyte tethering or rolling
0.54	GO:2000406	positive regulation of T cell migration
0.53	GO:0042130	negative regulation of T cell proliferation
0.53	GO:0045060	negative thymic T cell selection
0.52	GO:0001562	response to protozoan

0.59	GO:0030544	Hsp70 protein binding
0.42	GO:0019904	protein domain specific binding
0.42	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
0.37	GO:0051015	actin filament binding
0.37	GO:0005199	structural constituent of cell wall
0.36	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0008017	microtubule binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.54	GO:0009986	cell surface
0.54	GO:0001931	uropod
0.52	GO:0044421	extracellular region part
0.50	GO:0005902	microvillus
0.47	GO:0098552	side of membrane
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0031982	vesicle
0.43	GO:0032155	cell division site part
0.36	GO:0005618	cell wall
0.36	GO:0030117	membrane coat

0.42	EC:2.4.2.19	GO:0004514
0.42	KEGG:R03348	GO:0004514

sp|P13839|SIAL_RAT
Bone sialoprotein 2
Search

IBSP

0.97	Bone sialoprotein II

0.82	GO:0001503	ossification
0.72	GO:0007155	cell adhesion
0.68	GO:0031214	biomineral tissue development
0.65	GO:0030198	extracellular matrix organization
0.65	GO:0071363	cellular response to growth factor stimulus
0.61	GO:0045785	positive regulation of cell adhesion
0.40	GO:0007229	integrin-mediated signaling pathway
0.38	GO:0030154	cell differentiation
0.33	GO:0016310	phosphorylation
0.33	GO:0006464	cellular protein modification process

0.67	GO:0005178	integrin binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0004017	adenylate kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0017111	nucleoside-triphosphatase activity
0.32	GO:0008017	microtubule binding
0.32	GO:0050662	coenzyme binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.53	GO:0031982	vesicle
0.33	GO:0005634	nucleus
0.32	GO:0010494	cytoplasmic stress granule
0.32	GO:0005694	chromosome
0.32	GO:0043233	organelle lumen
0.31	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0004674

sp|P13852|PRIO_RAT
Major prion protein
Search

PRNP

0.81	Prion protein type B (Fragment)

0.78	GO:0051260	protein homooligomerization
0.54	GO:1902938	regulation of intracellular calcium activated chloride channel activity
0.53	GO:0071280	cellular response to copper ion
0.53	GO:1904646	cellular response to amyloid-beta
0.53	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.52	GO:1902951	negative regulation of dendritic spine maintenance
0.52	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade
0.52	GO:0043525	positive regulation of neuron apoptotic process
0.52	GO:1990535	neuron projection maintenance
0.52	GO:1902430	negative regulation of amyloid-beta formation

0.55	GO:0031802	type 5 metabotropic glutamate receptor binding
0.54	GO:0046872	metal ion binding
0.52	GO:0001540	amyloid-beta binding
0.49	GO:0002020	protease binding
0.47	GO:0032403	protein complex binding
0.47	GO:0008017	microtubule binding
0.47	GO:0042802	identical protein binding
0.46	GO:0005539	glycosaminoglycan binding
0.42	GO:0004872	receptor activity
0.42	GO:0004871	signal transducer activity

0.58	GO:0098857	membrane microdomain
0.55	GO:0005886	plasma membrane
0.53	GO:0031225	anchored component of membrane
0.53	GO:0106003	amyloid-beta complex
0.52	GO:0005794	Golgi apparatus
0.51	GO:0016234	inclusion body
0.49	GO:0030425	dendrite
0.49	GO:0031965	nuclear membrane
0.47	GO:0009986	cell surface
0.45	GO:0005829	cytosol

sp|P13941|CO3A1_RAT
Collagen alpha-1(III) chain
Search

COL3A1

0.76	Collagen type III alpha 1 chain

0.58	GO:0030199	collagen fibril organization
0.57	GO:0060414	aorta smooth muscle tissue morphogenesis
0.56	GO:2001223	negative regulation of neuron migration
0.56	GO:0043588	skin development
0.55	GO:0071230	cellular response to amino acid stimulus
0.55	GO:0071560	cellular response to transforming growth factor beta stimulus
0.55	GO:0035025	positive regulation of Rho protein signal transduction
0.55	GO:0018149	peptide cross-linking
0.54	GO:0042060	wound healing
0.54	GO:0021987	cerebral cortex development

0.80	GO:0005201	extracellular matrix structural constituent
0.60	GO:0048407	platelet-derived growth factor binding
0.57	GO:0002020	protease binding
0.55	GO:0005178	integrin binding
0.53	GO:0046332	SMAD binding
0.39	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding

0.74	GO:0005581	collagen trimer
0.60	GO:0098643	banded collagen fibril
0.51	GO:0005615	extracellular space
0.38	GO:0030141	secretory granule
0.38	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|P14056|ARAF_RAT
Serine/threonine-protein kinase A-Raf
Search

ARAF

0.97	A-Raf proto-oncogene serine/threonine-protein kinase

0.64	GO:0020021	immortalization of host cell
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.54	GO:0000186	activation of MAPKK activity
0.53	GO:0009968	negative regulation of signal transduction
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.51	GO:0043066	negative regulation of apoptotic process
0.50	GO:1900107	regulation of nodal signaling pathway
0.49	GO:0030154	cell differentiation
0.48	GO:0007167	enzyme linked receptor protein signaling pathway

0.77	GO:0005057	signal transducer activity, downstream of receptor
0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0031434	mitogen-activated protein kinase kinase binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.48	GO:0046332	SMAD binding
0.39	GO:0017016	Ras GTPase binding
0.39	GO:0042802	identical protein binding

0.48	GO:0005739	mitochondrion
0.47	GO:0005829	cytosol
0.42	GO:0031143	pseudopodium
0.40	GO:0016607	nuclear speck
0.39	GO:0005794	Golgi apparatus
0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.69

GO:0004674

sp|P14095|GROA_RAT
Growth-regulated alpha protein
Search

0.89	C-X-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.72	GO:0006952	defense response
0.53	GO:0090023	positive regulation of neutrophil chemotaxis
0.52	GO:0002237	response to molecule of bacterial origin
0.51	GO:0070098	chemokine-mediated signaling pathway
0.49	GO:0042127	regulation of cell proliferation
0.49	GO:0033993	response to lipid
0.47	GO:1901700	response to oxygen-containing compound

0.84	GO:0008009	chemokine activity
0.55	GO:0045236	CXCR chemokine receptor binding
0.43	GO:0008083	growth factor activity
0.36	GO:0008201	heparin binding
0.35	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.34	GO:0008047	enzyme activator activity
0.33	GO:0016787	hydrolase activity

0.71	GO:0005615	extracellular space
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.30	GO:0016020	membrane

0.35	EC:1.5.1.5	GO:0004488
0.35	KEGG:R01220	GO:0004488

sp|P14137|CP11A_RAT
Cholesterol side-chain cleavage enzyme, mitochondrial
Search

CYP11A1

0.96	Cholesterol side-chain cleavage enzyme, mitochondrial

0.86	GO:0006700	C21-steroid hormone biosynthetic process
0.82	GO:0008203	cholesterol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.38	GO:0042359	vitamin D metabolic process
0.38	GO:0060429	epithelium development
0.38	GO:0033595	response to genistein
0.38	GO:0018879	biphenyl metabolic process
0.38	GO:0018963	phthalate metabolic process
0.37	GO:0018894	dibenzo-p-dioxin metabolic process
0.37	GO:0033591	response to L-ascorbic acid

0.86	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.36	GO:0015485	cholesterol binding
0.35	GO:0004507	steroid 11-beta-monooxygenase activity
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.36	GO:0043204	perikaryon
0.35	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:1.14.15.6

GO:0008386

sp|P14141|CAH3_RAT
Carbonic anhydrase 3
Search

CA3

0.97	Carbonic anhydrase 3

0.71	GO:0006730	one-carbon metabolic process
0.41	GO:0038166	angiotensin-activated signaling pathway
0.41	GO:2000878	positive regulation of oligopeptide transport
0.41	GO:2001148	regulation of dipeptide transmembrane transport
0.41	GO:0044070	regulation of anion transport
0.40	GO:0015670	carbon dioxide transport
0.39	GO:0051453	regulation of intracellular pH
0.39	GO:0034764	positive regulation of transmembrane transport
0.39	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.39	GO:0045471	response to ethanol

0.77	GO:0004089	carbonate dehydratase activity
0.62	GO:0008270	zinc ion binding
0.49	GO:0016151	nickel cation binding
0.42	GO:0004064	arylesterase activity
0.36	GO:0016791	phosphatase activity

0.49	GO:0005829	cytosol
0.43	GO:0043209	myelin sheath
0.39	GO:0045177	apical part of cell
0.36	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0005886	plasma membrane

0.77

EC:4.2.1.1

GO:0004089

sp|P14173|DDC_RAT
Aromatic-L-amino-acid decarboxylase
Search

DDC

0.74	Aromatic-L-amino-acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.48	GO:0009636	response to toxic substance
0.45	GO:0042416	dopamine biosynthetic process
0.43	GO:0033076	isoquinoline alkaloid metabolic process
0.42	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.42	GO:0007275	multicellular organism development
0.42	GO:0052314	phytoalexin metabolic process
0.42	GO:0060322	head development
0.42	GO:0042427	serotonin biosynthetic process
0.42	GO:0071312	cellular response to alkaloid

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.49	GO:0019899	enzyme binding
0.39	GO:0019904	protein domain specific binding
0.39	GO:0016597	amino acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0008021	synaptic vesicle
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.68

EC:4.1.1

GO:0016831

sp|P14200|MCH_RAT
Pro-MCH
Search

PMCH

0.97	Pro-melanin-concentrating hormone

0.78	GO:0007268	chemical synaptic transmission
0.76	GO:0010469	regulation of receptor activity
0.62	GO:0007631	feeding behavior
0.41	GO:0007218	neuropeptide signaling pathway
0.38	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep
0.38	GO:0032227	negative regulation of synaptic transmission, dopaminergic
0.37	GO:0007595	lactation
0.37	GO:0045776	negative regulation of blood pressure
0.37	GO:0048168	regulation of neuronal synaptic plasticity
0.37	GO:0002027	regulation of heart rate

0.87	GO:0030354	melanin-concentrating hormone activity
0.39	GO:0031777	type 1 melanin-concentrating hormone receptor binding

0.49	GO:0005634	nucleus
0.40	GO:0005576	extracellular region
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P14270|PDE4D_RAT
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Search

PDE4D

0.55	Phosphodiesterase

0.61	GO:0007165	signal transduction
0.54	GO:1901898	negative regulation of relaxation of cardiac muscle
0.53	GO:0071872	cellular response to epinephrine stimulus
0.52	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.52	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.52	GO:0045822	negative regulation of heart contraction
0.52	GO:0032754	positive regulation of interleukin-5 production
0.51	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.51	GO:0086004	regulation of cardiac muscle cell contraction
0.51	GO:0030593	neutrophil chemotaxis

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.51	GO:0051117	ATPase binding
0.51	GO:0044325	ion channel binding
0.50	GO:0097110	scaffold protein binding
0.50	GO:0030552	cAMP binding
0.39	GO:0008144	drug binding
0.38	GO:0031698	beta-2 adrenergic receptor binding
0.36	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0017124	SH3 domain binding

0.49	GO:0034704	calcium channel complex
0.48	GO:0031965	nuclear membrane
0.48	GO:0005813	centrosome
0.45	GO:0005829	cytosol
0.42	GO:0044459	plasma membrane part
0.36	GO:0045177	apical part of cell
0.35	GO:0030016	myofibril
0.34	GO:0005794	Golgi apparatus

0.80

GO:0004114

sp|P14272|KLKB1_RAT
Plasma kallikrein
Search

F11

0.87	Coagulation factor XI

0.82	GO:0007596	blood coagulation
0.68	GO:0051919	positive regulation of fibrinolysis
0.65	GO:0031639	plasminogen activation
0.38	GO:0072376	protein activation cascade

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0008201	heparin binding
0.39	GO:0070009	serine-type aminopeptidase activity
0.37	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P14408|FUMH_RAT
Fumarate hydratase, mitochondrial
Search

0.53	Fumarate hydratase, mitochondrial

0.78	GO:0006106	fumarate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.52	GO:0048873	homeostasis of number of cells within a tissue
0.46	GO:0006108	malate metabolic process
0.34	GO:0022900	electron transport chain
0.34	GO:0007034	vacuolar transport

0.79	GO:0004333	fumarate hydratase activity
0.36	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.35	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0005515	protein binding

0.77	GO:0045239	tricarboxylic acid cycle enzyme complex
0.45	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0044446	intracellular organelle part
0.34	GO:0031090	organelle membrane
0.34	GO:0031975	envelope
0.33	GO:0031974	membrane-enclosed lumen

0.79	EC:4.2.1.2	GO:0004333
0.79	KEGG:R01082	GO:0004333

sp|P14423|PA2GA_RAT
Phospholipase A2, membrane associated
Search

0.69	Group IID secretory phospholipase A2

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.50	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.49	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.48	GO:0042130	negative regulation of T cell proliferation
0.44	GO:0046486	glycerolipid metabolic process
0.40	GO:0010518	positive regulation of phospholipase activity
0.37	GO:0034374	low-density lipoprotein particle remodeling
0.36	GO:0010744	positive regulation of macrophage derived foam cell differentiation

0.83	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.83	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.82	GO:0004623	phospholipase A2 activity
0.70	GO:0005509	calcium ion binding
0.48	GO:0043395	heparan sulfate proteoglycan binding
0.46	GO:0008201	heparin binding
0.46	GO:0005543	phospholipid binding
0.35	GO:0090729	toxin activity
0.33	GO:0008061	chitin binding

0.66	GO:0005576	extracellular region
0.44	GO:0005783	endoplasmic reticulum
0.38	GO:0030141	secretory granule
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0071944	cell periphery
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0072556	other organism presynaptic membrane
0.34	GO:0031984	organelle subcompartment
0.33	GO:0099568	cytoplasmic region
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.82

EC:3.1.1.4

GO:0004623

sp|P14480|FIBB_RAT
Fibrinogen beta chain
Search

FGB

0.72	Fibrinogen beta chain

0.82	GO:0030168	platelet activation
0.75	GO:0051258	protein polymerization
0.62	GO:0072378	blood coagulation, fibrin clot formation
0.62	GO:0043152	induction of bacterial agglutination
0.61	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.61	GO:0042730	fibrinolysis
0.60	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.60	GO:0045907	positive regulation of vasoconstriction
0.60	GO:2000352	negative regulation of endothelial cell apoptotic process
0.59	GO:0031639	plasminogen activation

0.78	GO:0030674	protein binding, bridging
0.70	GO:0005102	receptor binding
0.56	GO:0050839	cell adhesion molecule binding
0.54	GO:0051087	chaperone binding
0.46	GO:0005198	structural molecule activity
0.32	GO:0046872	metal ion binding

0.85	GO:0005577	fibrinogen complex
0.60	GO:0031091	platelet alpha granule
0.56	GO:0009897	external side of plasma membrane
0.54	GO:0005938	cell cortex
0.51	GO:0005783	endoplasmic reticulum
0.41	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome
0.35	GO:0034774	secretory granule lumen

sp|P14562|LAMP1_RAT
Lysosome-associated membrane glycoprotein 1
Search

LAMP1

0.94	Lysosomal-associated membrane glycoprotein 1

0.59	GO:0043323	positive regulation of natural killer cell degranulation
0.58	GO:1902513	regulation of organelle transport along microtubule
0.58	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.57	GO:0090160	Golgi to lysosome transport
0.53	GO:0050821	protein stabilization
0.49	GO:0072594	establishment of protein localization to organelle
0.44	GO:0048102	autophagic cell death
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0007283	spermatogenesis
0.34	GO:0006511	ubiquitin-dependent protein catabolic process

0.51	GO:0019904	protein domain specific binding
0.49	GO:0019899	enzyme binding
0.36	GO:0104005	hijacked molecular function
0.34	GO:0005509	calcium ion binding
0.34	GO:0004252	serine-type endopeptidase activity

0.82	GO:0005765	lysosomal membrane
0.58	GO:0044194	cytolytic granule
0.58	GO:0032010	phagolysosome
0.57	GO:0044754	autolysosome
0.57	GO:0030670	phagocytic vesicle membrane
0.56	GO:0005771	multivesicular body
0.55	GO:0042470	melanosome
0.55	GO:0042383	sarcolemma
0.54	GO:0008021	synaptic vesicle
0.54	GO:0009897	external side of plasma membrane

0.34

GO:0004252

sp|P14600|NK1R_RAT
Substance-P receptor
Search

TACR1

0.97	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.61	GO:1902093	positive regulation of flagellated sperm motility
0.55	GO:0070472	regulation of uterine smooth muscle contraction
0.54	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.53	GO:0048265	response to pain
0.48	GO:0045987	positive regulation of smooth muscle contraction
0.44	GO:0007268	chemical synaptic transmission
0.42	GO:0072347	response to anesthetic
0.42	GO:0043279	response to alkaloid
0.41	GO:0060359	response to ammonium ion

0.86	GO:0004995	tachykinin receptor activity
0.34	GO:0050254	rhodopsin kinase activity
0.33	GO:0005515	protein binding

0.59	GO:0097225	sperm midpiece
0.58	GO:0061827	sperm head
0.56	GO:0005886	plasma membrane
0.38	GO:0030425	dendrite
0.38	GO:0044297	cell body
0.37	GO:0009986	cell surface
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0050254

sp|P14604|ECHM_RAT
Enoyl-CoA hydratase, mitochondrial
Search

ECHS1

0.38	Enoyl-CoA hydrataseserine-threonine

0.52	GO:0006635	fatty acid beta-oxidation
0.33	GO:0005996	monosaccharide metabolic process

0.53	GO:0004300	enoyl-CoA hydratase activity
0.35	GO:0016508	long-chain-enoyl-CoA hydratase activity
0.33	GO:0048029	monosaccharide binding
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0016853	isomerase activity
0.32	GO:0003723	RNA binding

0.44	GO:0005739	mitochondrion
0.37	GO:0043233	organelle lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.53

EC:4.2.1.17

GO:0004300

sp|P14630|APOM_RAT
Apolipoprotein M
Search

APOM

0.97	Apolipoprotein M

0.87	GO:0034444	regulation of plasma lipoprotein oxidation
0.87	GO:0034384	high-density lipoprotein particle clearance
0.86	GO:0034380	high-density lipoprotein particle assembly
0.86	GO:0034375	high-density lipoprotein particle remodeling
0.86	GO:0043691	reverse cholesterol transport
0.85	GO:0033344	cholesterol efflux
0.77	GO:0051241	negative regulation of multicellular organismal process
0.76	GO:0051129	negative regulation of cellular component organization
0.74	GO:0042157	lipoprotein metabolic process
0.68	GO:0098869	cellular oxidant detoxification

0.76	GO:0005319	lipid transporter activity
0.74	GO:0005543	phospholipid binding
0.69	GO:0016209	antioxidant activity
0.37	GO:0005515	protein binding

0.88	GO:0034365	discoidal high-density lipoprotein particle
0.86	GO:0034366	spherical high-density lipoprotein particle
0.86	GO:0034362	low-density lipoprotein particle
0.85	GO:0034361	very-low-density lipoprotein particle
0.45	GO:0070062	extracellular exosome
0.38	GO:0005887	integral component of plasma membrane

sp|P14644|PDE4C_RAT
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Fragment)
Search

PDE4D

0.56	Phosphodiesterase

0.61	GO:0007165	signal transduction
0.45	GO:0006198	cAMP catabolic process
0.45	GO:1901898	negative regulation of relaxation of cardiac muscle
0.44	GO:0032754	positive regulation of interleukin-5 production
0.44	GO:0071872	cellular response to epinephrine stimulus
0.44	GO:0032743	positive regulation of interleukin-2 production
0.43	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.43	GO:0032729	positive regulation of interferon-gamma production
0.43	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.43	GO:0045822	negative regulation of heart contraction

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.43	GO:0097110	scaffold protein binding
0.43	GO:0051117	ATPase binding
0.43	GO:0044325	ion channel binding
0.43	GO:0030552	cAMP binding
0.36	GO:0008144	drug binding
0.35	GO:0003924	GTPase activity
0.34	GO:0005525	GTP binding

0.47	GO:0005929	cilium
0.42	GO:0034704	calcium channel complex
0.42	GO:0031965	nuclear membrane
0.41	GO:0005813	centrosome
0.40	GO:0005829	cytosol
0.37	GO:0044459	plasma membrane part
0.35	GO:0005615	extracellular space
0.34	GO:0045177	apical part of cell

0.80

GO:0004114

sp|P14646|PDE4B_RAT
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Search

PDE4B

0.57	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.57	GO:0032743	positive regulation of interleukin-2 production
0.56	GO:0032729	positive regulation of interferon-gamma production
0.56	GO:0001780	neutrophil homeostasis
0.56	GO:0006198	cAMP catabolic process
0.54	GO:0030593	neutrophil chemotaxis
0.53	GO:0002253	activation of immune response
0.53	GO:0071222	cellular response to lipopolysaccharide
0.52	GO:0035690	cellular response to drug
0.43	GO:0006939	smooth muscle contraction

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.55	GO:0030552	cAMP binding
0.54	GO:0046872	metal ion binding
0.52	GO:0043015	gamma-tubulin binding
0.38	GO:0044325	ion channel binding

0.55	GO:0060076	excitatory synapse
0.54	GO:0043197	dendritic spine
0.53	GO:0014069	postsynaptic density
0.53	GO:0000930	gamma-tubulin complex
0.52	GO:0008021	synaptic vesicle
0.51	GO:0005813	centrosome
0.47	GO:0005829	cytosol
0.41	GO:0071944	cell periphery
0.38	GO:0030018	Z disc
0.38	GO:0034704	calcium channel complex

0.79

GO:0004114

sp|P14650|PERT_RAT
Thyroid peroxidase
Search

TPO

0.97	Myeloid-specific peroxidase

0.84	GO:0006590	thyroid hormone generation
0.67	GO:0006979	response to oxidative stress
0.65	GO:0098869	cellular oxidant detoxification
0.57	GO:0035162	embryonic hemopoiesis
0.50	GO:0055114	oxidation-reduction process
0.42	GO:0042446	hormone biosynthetic process
0.41	GO:0042744	hydrogen peroxide catabolic process
0.37	GO:1902170	cellular response to reactive nitrogen species
0.37	GO:0097366	response to bronchodilator
0.37	GO:0006952	defense response

0.84	GO:0004447	iodide peroxidase activity
0.62	GO:0005509	calcium ion binding
0.60	GO:0020037	heme binding

0.45	GO:0005615	extracellular space
0.45	GO:0005739	mitochondrion
0.37	GO:0009986	cell surface
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:1.11.1.8

GO:0004447

sp|P14659|HSP72_RAT
Heat shock-related 70 kDa protein 2
Search

HSPA2

0.61	Inducible heat shock protein 70

0.64	GO:0009409	response to cold
0.60	GO:0009408	response to heat
0.56	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.56	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.55	GO:0070194	synaptonemal complex disassembly
0.54	GO:0090084	negative regulation of inclusion body assembly
0.54	GO:0007141	male meiosis I
0.51	GO:0007286	spermatid development
0.48	GO:0042026	protein refolding
0.39	GO:0032570	response to progesterone

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0051861	glycolipid binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.53	GO:0097718	disordered domain specific binding
0.47	GO:0019899	enzyme binding
0.46	GO:0051082	unfolded protein binding
0.40	GO:0033142	progesterone receptor binding
0.35	GO:0055131	C3HC4-type RING finger domain binding

0.54	GO:0036128	CatSper complex
0.54	GO:0072687	meiotic spindle
0.54	GO:0001673	male germ cell nucleus
0.52	GO:0000795	synaptonemal complex
0.51	GO:0043209	myelin sheath
0.48	GO:0009986	cell surface
0.46	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0043204	perikaryon
0.38	GO:0072562	blood microparticle

0.33

GO:0016887

sp|P14668|ANXA5_RAT
Annexin A5
Search

ANXA5

0.57

Annexin

0.85	GO:0050819	negative regulation of coagulation
0.49	GO:0010033	response to organic substance
0.42	GO:2000145	regulation of cell motility
0.41	GO:0007596	blood coagulation
0.36	GO:1902721	negative regulation of prolactin secretion
0.36	GO:0071284	cellular response to lead ion
0.36	GO:0006816	calcium ion transport
0.36	GO:0042981	regulation of apoptotic process
0.35	GO:0002576	platelet degranulation
0.35	GO:1900047	negative regulation of hemostasis

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.36	GO:0015085	calcium ion transmembrane transporter activity
0.36	GO:0035374	chondroitin sulfate binding
0.35	GO:0017046	peptide hormone binding
0.35	GO:0004859	phospholipase inhibitor activity
0.35	GO:0008201	heparin binding
0.34	GO:0060090	molecular adaptor activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

0.59	GO:0072563	endothelial microparticle
0.53	GO:0009897	external side of plasma membrane
0.38	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome
0.36	GO:0005925	focal adhesion
0.35	GO:0014704	intercalated disc
0.35	GO:0043204	perikaryon
0.35	GO:0043679	axon terminus
0.35	GO:0042383	sarcolemma
0.35	GO:0030425	dendrite

sp|P14669|ANXA3_RAT
Annexin A3
Search

0.64

Annexin

0.66	GO:0043086	negative regulation of catalytic activity
0.57	GO:0006909	phagocytosis
0.56	GO:0043312	neutrophil degranulation
0.56	GO:0010595	positive regulation of endothelial cell migration
0.55	GO:0045766	positive regulation of angiogenesis
0.53	GO:0051091	positive regulation of DNA binding transcription factor activity
0.51	GO:0042742	defense response to bacterium
0.41	GO:0051241	negative regulation of multicellular organismal process
0.41	GO:0031099	regeneration
0.41	GO:0051592	response to calcium ion

0.81	GO:0005544	calcium-dependent phospholipid binding
0.79	GO:0004859	phospholipase inhibitor activity
0.70	GO:0005509	calcium ion binding
0.59	GO:0048306	calcium-dependent protein binding
0.47	GO:0008429	phosphatidylethanolamine binding
0.43	GO:0044548	S100 protein binding
0.40	GO:0098641	cadherin binding involved in cell-cell adhesion
0.40	GO:0033676	double-stranded DNA-dependent ATPase activity
0.39	GO:0036310	annealing helicase activity
0.39	GO:0030674	protein binding, bridging

0.58	GO:0042581	specific granule
0.56	GO:0030670	phagocytic vesicle membrane
0.50	GO:0005829	cytosol
0.42	GO:0030496	midbody
0.42	GO:0005886	plasma membrane
0.42	GO:0005764	lysosome
0.41	GO:0005654	nucleoplasm
0.41	GO:0044430	cytoskeletal part
0.41	GO:0005635	nuclear envelope
0.40	GO:0015630	microtubule cytoskeleton

sp|P14730|WFD18_RAT
WAP four-disulfide core domain protein 18 (Fragment)
Search

0.73	Extracellular peptidase inhibitor

0.76	GO:0010466	negative regulation of peptidase activity
0.42	GO:0052548	regulation of endopeptidase activity
0.36	GO:0097155	fasciculation of sensory neuron axon
0.36	GO:0048920	posterior lateral line neuromast primordium migration
0.36	GO:0007411	axon guidance
0.36	GO:0097154	GABAergic neuron differentiation
0.36	GO:0071542	dopaminergic neuron differentiation
0.36	GO:0021772	olfactory bulb development
0.35	GO:0007155	cell adhesion
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway

0.76	GO:0030414	peptidase inhibitor activity
0.42	GO:0061135	endopeptidase regulator activity
0.34	GO:0008201	heparin binding
0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0008061	chitin binding
0.33	GO:0005515	protein binding
0.33	GO:0008233	peptidase activity

0.66	GO:0005576	extracellular region
0.35	GO:0009986	cell surface
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0008233

sp|P14740|DPP4_RAT
Dipeptidyl peptidase 4
Search

DPP4

0.86	Venom dipeptidylpeptidase IV

0.61

GO:0006508

proteolysis

0.69

GO:0004252

serine-type endopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.69

GO:0004252

sp|P14841|CYTC_RAT
Cystatin-C
Search

0.74	Cystatin-C

0.76	GO:0010951	negative regulation of endopeptidase activity
0.62	GO:0010711	negative regulation of collagen catabolic process
0.62	GO:0060311	negative regulation of elastin catabolic process
0.61	GO:0060313	negative regulation of blood vessel remodeling
0.60	GO:0010716	negative regulation of extracellular matrix disassembly
0.53	GO:2000116	regulation of cysteine-type endopeptidase activity
0.51	GO:0097435	supramolecular fiber organization
0.50	GO:0006952	defense response
0.49	GO:0042747	circadian sleep/wake cycle, REM sleep
0.47	GO:0060009	Sertoli cell development

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.62	GO:0002020	protease binding
0.57	GO:0001540	amyloid-beta binding
0.51	GO:0042802	identical protein binding

0.56	GO:0005615	extracellular space
0.46	GO:0005771	multivesicular body
0.45	GO:0005604	basement membrane
0.45	GO:0043025	neuronal cell body
0.44	GO:0043292	contractile fiber
0.44	GO:0030424	axon
0.44	GO:0031965	nuclear membrane
0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005764	lysosome
0.42	GO:1903561	extracellular vesicle

sp|P14842|5HT2A_RAT
5-hydroxytryptamine receptor 2A
Search

HTR2A

0.97	5-hydroxytryptamine (Serotonin) receptor 2 A

0.80	GO:0006939	smooth muscle contraction
0.80	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.79	GO:0050795	regulation of behavior
0.77	GO:0046883	regulation of hormone secretion
0.60	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.59	GO:0007202	activation of phospholipase C activity
0.57	GO:0051209	release of sequestered calcium ion into cytosol
0.57	GO:0014065	phosphatidylinositol 3-kinase signaling
0.56	GO:0045821	positive regulation of glycolytic process
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.80	GO:0099589	serotonin receptor activity
0.77	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.77	GO:0008227	G-protein coupled amine receptor activity
0.61	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
0.59	GO:0051378	serotonin binding
0.41	GO:0001965	G-protein alpha-subunit binding
0.39	GO:0032403	protein complex binding
0.36	GO:0018738	S-formylglutathione hydrolase activity
0.36	GO:0104005	hijacked molecular function

0.82	GO:0043198	dendritic shaft
0.63	GO:0005887	integral component of plasma membrane
0.45	GO:0005901	caveola
0.44	GO:0030424	axon
0.42	GO:0031410	cytoplasmic vesicle
0.42	GO:0070852	cell body fiber
0.40	GO:0043025	neuronal cell body
0.37	GO:0005829	cytosol

0.36	EC:3.1.2.12	GO:0018738
0.36	KEGG:R00527	GO:0018738

sp|P14844|CCL2_RAT
C-C motif chemokine 2
Search

CCL2

0.57	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.67	GO:0071347	cellular response to interleukin-1
0.66	GO:0050900	leukocyte migration
0.66	GO:0071356	cellular response to tumor necrosis factor
0.65	GO:0002688	regulation of leukocyte chemotaxis
0.63	GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages
0.62	GO:0006954	inflammatory response
0.61	GO:0002687	positive regulation of leukocyte migration

0.84	GO:0008009	chemokine activity
0.67	GO:0031727	CCR2 chemokine receptor binding
0.55	GO:0008201	heparin binding
0.47	GO:0031726	CCR1 chemokine receptor binding

0.73	GO:0005615	extracellular space
0.59	GO:0044299	C-fiber
0.55	GO:0043204	perikaryon
0.54	GO:0043679	axon terminus
0.53	GO:0005791	rough endoplasmic reticulum
0.53	GO:0030139	endocytic vesicle
0.53	GO:0030425	dendrite
0.52	GO:0048471	perinuclear region of cytoplasm

sp|P14881|CRBA1_RAT
Beta-crystallin A3
Search

CRYBA1

0.97	Beta crystallin A3 chain transcript CN (Fragment)

0.66	GO:0007601	visual perception
0.45	GO:2000210	positive regulation of anoikis
0.44	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.44	GO:0043010	camera-type eye development
0.43	GO:0051898	negative regulation of protein kinase B signaling
0.43	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.43	GO:0032007	negative regulation of TOR signaling
0.43	GO:0001818	negative regulation of cytokine production

0.68	GO:0005212	structural constituent of eye lens
0.39	GO:0042803	protein homodimerization activity

0.37	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|P14882|PCCA_RAT
Propionyl-CoA carboxylase alpha chain, mitochondrial
Search

PCCA

0.77	Propionyl-Coenzyme A carboxylase, alpha polypeptide

0.76	GO:0004075	biotin carboxylase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.46	GO:0004658	propionyl-CoA carboxylase activity
0.42	GO:0019899	enzyme binding
0.34	GO:0003676	nucleic acid binding

0.39

GO:0005739

mitochondrion

0.76

EC:6.3.4.14

GO:0004075

sp|P14925|AMD_RAT
Peptidyl-glycine alpha-amidating monooxygenase
Search

PAM

0.94	Peptidyl-glycine alpha-amidating monooxygenase

0.63	GO:0001519	peptide amidation
0.52	GO:0055114	oxidation-reduction process
0.42	GO:0018032	protein amidation
0.40	GO:0007595	lactation
0.40	GO:0060135	maternal process involved in female pregnancy
0.40	GO:0032355	response to estradiol
0.40	GO:0051384	response to glucocorticoid
0.40	GO:0042476	odontogenesis
0.40	GO:0022602	ovulation cycle process
0.40	GO:0009268	response to pH

0.82	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.69	GO:0005507	copper ion binding
0.63	GO:0004598	peptidylamidoglycolate lyase activity
0.47	GO:0008270	zinc ion binding
0.40	GO:0031418	L-ascorbic acid binding
0.39	GO:0019901	protein kinase binding
0.37	GO:0005509	calcium ion binding

0.41	GO:0030659	cytoplasmic vesicle membrane
0.40	GO:0043204	perikaryon
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0030141	secretory granule
0.39	GO:0030133	transport vesicle
0.39	GO:0005802	trans-Golgi network
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0043005	neuron projection
0.38	GO:0009986	cell surface

0.82

EC:1.14.17

GO:0016715

sp|P14942|GSTA4_RAT
Glutathione S-transferase alpha-4
Search

0.42	Glutathione S-transferase

0.40	GO:0043390	aflatoxin B1 metabolic process
0.40	GO:0006749	glutathione metabolic process
0.38	GO:0006805	xenobiotic metabolic process
0.38	GO:0071285	cellular response to lithium ion
0.38	GO:0009636	response to toxic substance
0.38	GO:0010043	response to zinc ion
0.36	GO:0042493	response to drug
0.35	GO:0006950	response to stress
0.34	GO:0016567	protein ubiquitination

0.77	GO:0004364	glutathione transferase activity
0.38	GO:0043295	glutathione binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0008144	drug binding

0.36	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.34	GO:0005615	extracellular space

0.77	EC:2.5.1.18	GO:0004364
0.34	KEGG:R03876	GO:0004842

sp|P15063|MYCB_RAT
Protein B-Myc
Search

MYC

0.84	Brain expressed myelocytomatosis oncogene

0.57	GO:0006355	regulation of transcription, DNA-templated
0.53	GO:0045656	negative regulation of monocyte differentiation
0.52	GO:0048146	positive regulation of fibroblast proliferation
0.51	GO:0010332	response to gamma radiation
0.51	GO:2000573	positive regulation of DNA biosynthetic process
0.51	GO:0060070	canonical Wnt signaling pathway
0.51	GO:2001022	positive regulation of response to DNA damage stimulus
0.50	GO:0032204	regulation of telomere maintenance
0.50	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.50	GO:0050679	positive regulation of epithelial cell proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0046983	protein dimerization activity
0.52	GO:0070888	E-box binding
0.47	GO:0032403	protein complex binding
0.38	GO:0070491	repressing transcription factor binding
0.38	GO:0033613	activating transcription factor binding
0.38	GO:0071074	eukaryotic initiation factor eIF2 binding
0.36	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0003729	mRNA binding
0.33	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.49	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0042025	host cell nucleus
0.36	GO:0005791	rough endoplasmic reticulum
0.36	GO:0030424	axon
0.36	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005739	mitochondrion
0.34	GO:0043234	protein complex

sp|P15083|PIGR_RAT
Polymeric immunoglobulin receptor
Search

PIGR

0.97	Polymeric immunoglobulin receptor

0.80	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
0.75	GO:0038093	Fc receptor signaling pathway
0.75	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.74	GO:0043113	receptor clustering
0.74	GO:0007173	epidermal growth factor receptor signaling pathway
0.45	GO:0001895	retina homeostasis
0.40	GO:0043312	neutrophil degranulation

0.81	GO:0001792	polymeric immunoglobulin receptor activity
0.42	GO:0005154	epidermal growth factor receptor binding

0.67	GO:0043235	receptor complex
0.63	GO:0005615	extracellular space
0.51	GO:0005886	plasma membrane
0.44	GO:1903561	extracellular vesicle
0.42	GO:0055038	recycling endosome membrane
0.41	GO:0035577	azurophil granule membrane
0.40	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

sp|P15087|CBPE_RAT
Carboxypeptidase E
Search

CPE

0.96	Carboxypeptidase E

0.62	GO:0030070	insulin processing
0.59	GO:0003214	cardiac left ventricle morphogenesis
0.53	GO:0016055	Wnt signaling pathway
0.51	GO:0072657	protein localization to membrane
0.37	GO:2000173	negative regulation of branching morphogenesis of a nerve
0.36	GO:0034230	enkephalin processing
0.35	GO:0007218	neuropeptide signaling pathway
0.35	GO:0043171	peptide catabolic process
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.75	GO:0004181	metallocarboxypeptidase activity
0.61	GO:0008270	zinc ion binding
0.58	GO:0042043	neurexin family protein binding
0.54	GO:0050839	cell adhesion molecule binding
0.45	GO:0004185	serine-type carboxypeptidase activity
0.35	GO:0050897	cobalt ion binding
0.35	GO:0019904	protein domain specific binding

0.52	GO:0005615	extracellular space
0.51	GO:0005794	Golgi apparatus
0.47	GO:0043025	neuronal cell body
0.47	GO:0030141	secretory granule
0.46	GO:0097060	synaptic membrane
0.42	GO:0030658	transport vesicle membrane
0.37	GO:1903561	extracellular vesicle
0.35	GO:0030425	dendrite
0.35	GO:0045121	membrane raft
0.33	GO:0005634	nucleus

0.75

EC:3.4.17

GO:0004181

sp|P15127|INSR_RAT
Insulin receptor
Search

INSR

0.67	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.76	GO:0046777	protein autophosphorylation
0.55	GO:0060267	positive regulation of respiratory burst
0.55	GO:0045821	positive regulation of glycolytic process
0.54	GO:0045725	positive regulation of glycogen biosynthetic process
0.54	GO:0051290	protein heterotetramerization
0.54	GO:0032148	activation of protein kinase B activity
0.53	GO:0046326	positive regulation of glucose import
0.53	GO:0045429	positive regulation of nitric oxide biosynthetic process

0.83	GO:0043560	insulin receptor substrate binding
0.82	GO:0043548	phosphatidylinositol 3-kinase binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0051425	PTB domain binding
0.55	GO:0043559	insulin binding
0.55	GO:0031995	insulin-like growth factor II binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0031994	insulin-like growth factor I binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005899	insulin receptor complex
0.54	GO:0106003	amyloid-beta complex
0.52	GO:0005901	caveola
0.48	GO:0005635	nuclear envelope
0.45	GO:0031981	nuclear lumen
0.38	GO:0032809	neuronal cell body membrane
0.38	GO:0032590	dendrite membrane
0.37	GO:0009897	external side of plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0005768	endosome

0.80

EC:2.7.10.1

GO:0004714

sp|P15129|CP4B1_RAT
Cytochrome P450 4B1
Search

CYP4B1

0.97	Cytochrome P450 family 4 subfamily B polypeptide 1

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0018917	fluorene metabolic process
0.42	GO:0018879	biphenyl metabolic process
0.41	GO:0042738	exogenous drug catabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.63	GO:0004497	monooxygenase activity
0.40	GO:0015643	toxic substance binding
0.35	GO:0019825	oxygen binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P15146|MTAP2_RAT
Microtubule-associated protein 2
Search

MAP2

0.56	Microtubule-associated protein (Fragment)

0.85	GO:0021954	central nervous system neuron development
0.83	GO:0001578	microtubule bundle formation
0.58	GO:0048813	dendrite morphogenesis
0.55	GO:0050770	regulation of axonogenesis
0.54	GO:0030010	establishment of cell polarity
0.53	GO:0007409	axonogenesis
0.50	GO:0071310	cellular response to organic substance

0.73	GO:0015631	tubulin binding
0.60	GO:0002162	dystroglycan binding

0.72	GO:0005874	microtubule
0.59	GO:0097442	CA3 pyramidal cell dendrite
0.57	GO:0043198	dendritic shaft
0.55	GO:0014069	postsynaptic density
0.54	GO:0034399	nuclear periphery
0.54	GO:0043025	neuronal cell body
0.53	GO:0005730	nucleolus
0.50	GO:0005829	cytosol
0.44	GO:0005875	microtubule associated complex

sp|P15149|CP2A2_RAT
Cytochrome P450 2A2
Search

0.61	Cytochrome P450 family 2 subfamily A member 6

0.53	GO:0019373	epoxygenase P450 pathway
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0035634	response to stilbenoid
0.42	GO:0071276	cellular response to cadmium ion
0.42	GO:0090420	naphthalene-containing compound metabolic process
0.42	GO:0009804	coumarin metabolic process
0.39	GO:0042168	heme metabolic process
0.37	GO:0009636	response to toxic substance
0.36	GO:0007608	sensory perception of smell
0.35	GO:0017144	drug metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.54	GO:0008392	arachidonic acid epoxygenase activity
0.52	GO:0008395	steroid hydroxylase activity
0.42	GO:0019825	oxygen binding
0.41	GO:0008389	coumarin 7-hydroxylase activity
0.36	GO:0019899	enzyme binding

0.46	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0031090	organelle membrane
0.38	GO:0005881	cytoplasmic microtubule
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P15178|SYDC_RAT
Aspartate--tRNA ligase, cytoplasmic
Search

DARS

0.64	Aspartyl-tRNA synthetase

0.79	GO:0006422	aspartyl-tRNA aminoacylation
0.38	GO:0040007	growth
0.33	GO:0006461	protein complex assembly

0.79	GO:0004815	aspartate-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003676	nucleic acid binding
0.35	GO:0004046	aminoacylase activity
0.34	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.58	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.49	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.79

EC:6.1.1.12

GO:0004815

sp|P15205|MAP1B_RAT
Microtubule-associated protein 1B
Search

MAP1B

0.87	Microtubule-associated protein 1B

0.76	GO:0000226	microtubule cytoskeleton organization
0.74	GO:0007399	nervous system development
0.61	GO:0047497	mitochondrion transport along microtubule
0.60	GO:0061162	establishment of monopolar cell polarity
0.59	GO:0032387	negative regulation of intracellular transport
0.58	GO:0061387	regulation of extent of cell growth
0.58	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.58	GO:0016358	dendrite development
0.58	GO:0048588	developmental cell growth
0.58	GO:0030307	positive regulation of cell growth

0.74	GO:0008017	microtubule binding
0.38	GO:0005543	phospholipid binding
0.38	GO:0032403	protein complex binding
0.38	GO:0003779	actin binding
0.33	GO:0005519	cytoskeletal regulatory protein binding
0.32	GO:0005198	structural molecule activity

0.73	GO:0005874	microtubule
0.59	GO:0001750	photoreceptor outer segment
0.58	GO:0014069	postsynaptic density
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.42	GO:0097441	basal dendrite
0.42	GO:0097457	hippocampal mossy fiber
0.41	GO:0097440	apical dendrite
0.41	GO:0043196	varicosity
0.40	GO:0043197	dendritic spine

sp|P15207|ANDR_RAT
Androgen receptor
Search

0.76	Androgen receptor splice variant 5

0.80	GO:0030521	androgen receptor signaling pathway
0.63	GO:0045720	negative regulation of integrin biosynthetic process
0.58	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.58	GO:1903076	regulation of protein localization to plasma membrane
0.57	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.56	GO:0045726	positive regulation of integrin biosynthetic process
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0019102	male somatic sex determination
0.55	GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development
0.55	GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis

0.82	GO:0004882	androgen receptor activity
0.75	GO:0005496	steroid binding
0.63	GO:0005497	androgen binding
0.62	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.57	GO:0008013	beta-catenin binding
0.56	GO:0070974	POU domain binding
0.53	GO:0051117	ATPase binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0001085	RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.51	GO:0000785	chromatin
0.49	GO:0070013	intracellular organelle lumen
0.42	GO:0043234	protein complex
0.40	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.36	GO:0030425	dendrite
0.36	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|P15242|TEST2_RAT
Testin-2
Search

0.69	Cathepsin V

0.61	GO:0006508	proteolysis
0.48	GO:0044257	cellular protein catabolic process
0.46	GO:0010839	negative regulation of keratinocyte proliferation
0.46	GO:0046697	decidualization
0.46	GO:0031069	hair follicle morphogenesis
0.45	GO:2000249	regulation of actin cytoskeleton reorganization
0.44	GO:0097067	cellular response to thyroid hormone stimulus
0.44	GO:0030574	collagen catabolic process
0.42	GO:0002250	adaptive immune response
0.41	GO:0051604	protein maturation

0.72	GO:0008234	cysteine-type peptidase activity
0.47	GO:0042393	histone binding
0.46	GO:0004175	endopeptidase activity
0.46	GO:0097655	serpin family protein binding
0.44	GO:0001968	fibronectin binding
0.43	GO:0043394	proteoglycan binding
0.42	GO:0005518	collagen binding
0.41	GO:0004180	carboxypeptidase activity
0.37	GO:0030984	kininogen binding
0.35	GO:0042277	peptide binding

0.55	GO:0005764	lysosome
0.51	GO:0005615	extracellular space
0.42	GO:0031410	cytoplasmic vesicle
0.42	GO:0005730	nucleolus
0.36	GO:0005775	vacuolar lumen
0.36	GO:0043204	perikaryon
0.36	GO:0030054	cell junction
0.36	GO:0005902	microvillus
0.36	GO:0009897	external side of plasma membrane
0.36	GO:1903561	extracellular vesicle

0.72

GO:0008234

sp|P15257|HNF1A_RAT
Hepatocyte nuclear factor 1-alpha
Search

HNF1A

0.96	Hepatocyte nuclear factor 1-alpha-A

0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.64	GO:0035623	renal glucose absorption
0.61	GO:0048341	paraxial mesoderm formation
0.60	GO:0030073	insulin secretion
0.60	GO:0006699	bile acid biosynthetic process
0.60	GO:0045453	bone resorption
0.59	GO:0043691	reverse cholesterol transport
0.59	GO:0031018	endocrine pancreas development
0.59	GO:0015721	bile acid and bile salt transport
0.59	GO:0046323	glucose import

0.56	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0000987	proximal promoter sequence-specific DNA binding
0.53	GO:0042803	protein homodimerization activity
0.53	GO:0046982	protein heterodimerization activity
0.41	GO:0001221	transcription cofactor binding
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.61	GO:0005634	nucleus
0.57	GO:0001750	photoreceptor outer segment
0.53	GO:0005667	transcription factor complex
0.40	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|P15304|LIPS_RAT
Hormone-sensitive lipase
Search

LIPE

0.87	Hormone-sensitive lipase variant B

0.83	GO:0008203	cholesterol metabolic process
0.72	GO:0016042	lipid catabolic process
0.58	GO:0046339	diacylglycerol metabolic process
0.55	GO:0006641	triglyceride metabolic process
0.53	GO:0001676	long-chain fatty acid metabolic process
0.50	GO:0072329	monocarboxylic acid catabolic process
0.43	GO:0006363	termination of RNA polymerase I transcription
0.43	GO:0006361	transcription initiation from RNA polymerase I promoter
0.37	GO:0007565	female pregnancy
0.35	GO:0042221	response to chemical

0.75	GO:0016298	lipase activity
0.52	GO:0019901	protein kinase binding
0.50	GO:0052689	carboxylic ester hydrolase activity
0.47	GO:0017171	serine hydrolase activity
0.43	GO:0042134	rRNA primary transcript binding

0.56	GO:0005811	lipid droplet
0.50	GO:0005829	cytosol
0.43	GO:0005901	caveola
0.37	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.75	EC:3.1.1	GO:0016298
0.50	KEGG:R00630	GO:0052689

sp|P15337|CREB1_RAT
Cyclic AMP-responsive element-binding protein 1
Search

CREB1

0.86	Cyclic AMP-responsive element-binding protein 1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0033762	response to glucagon
0.49	GO:0060509	Type I pneumocyte differentiation
0.48	GO:0060430	lung saccule development
0.48	GO:0045600	positive regulation of fat cell differentiation
0.48	GO:0071294	cellular response to zinc ion
0.48	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.48	GO:0046889	positive regulation of lipid biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.47	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.44	GO:0001225	RNA polymerase II transcription coactivator binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.44	GO:1990763	arrestin family protein binding
0.43	GO:0042802	identical protein binding
0.43	GO:0035035	histone acetyltransferase binding
0.42	GO:0030544	Hsp70 protein binding

0.61	GO:0005634	nucleus
0.47	GO:0000791	euchromatin
0.44	GO:0005667	transcription factor complex
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0030424	axon
0.37	GO:0044429	mitochondrial part

sp|P15383|KCNE1_RAT
Potassium voltage-gated channel subfamily E member 1
Search

KCNE1

0.96	Potassium channel, voltage-gated subfamily E regulatory beta subunit 1

0.73	GO:0071804	cellular potassium ion transport
0.64	GO:0002070	epithelial cell maturation
0.64	GO:0086091	regulation of heart rate by cardiac conduction
0.63	GO:0060047	heart contraction
0.62	GO:0098662	inorganic cation transmembrane transport
0.62	GO:1902260	negative regulation of delayed rectifier potassium channel activity
0.54	GO:0006487	protein N-linked glycosylation
0.54	GO:0006493	protein O-linked glycosylation
0.52	GO:0090315	negative regulation of protein targeting to membrane
0.50	GO:1901387	positive regulation of voltage-gated calcium channel activity

0.78	GO:0005249	voltage-gated potassium channel activity
0.69	GO:0015459	potassium channel regulator activity
0.47	GO:0044325	ion channel binding
0.45	GO:0031433	telethonin binding
0.44	GO:0046982	protein heterodimerization activity

0.65	GO:0016324	apical plasma membrane
0.54	GO:0008076	voltage-gated potassium channel complex
0.54	GO:0045121	membrane raft
0.49	GO:0030018	Z disc
0.43	GO:0005794	Golgi apparatus
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0005764	lysosome
0.41	GO:0009986	cell surface

sp|P15384|KCNA3_RAT
Potassium voltage-gated channel subfamily A member 3
Search

KCNA3

0.94	Glibenclamide-sensitive voltage-gated potassium channel

0.78	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport

0.78	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.50	GO:0030424	axon
0.37	GO:0045121	membrane raft

sp|P15385|KCNA4_RAT
Potassium voltage-gated channel subfamily A member 4
Search

KCNA4

0.97	Potassium channel shaker alpha subunit pKv 1.4

0.76	GO:0051260	protein homooligomerization
0.75	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport

0.78	GO:0005249	voltage-gated potassium channel activity
0.67	GO:0030955	potassium ion binding
0.36	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.46	GO:0030424	axon
0.37	GO:0098889	intrinsic component of presynaptic membrane
0.36	GO:0098936	intrinsic component of postsynaptic membrane
0.36	GO:0099699	integral component of synaptic membrane
0.36	GO:0045121	membrane raft
0.36	GO:0043198	dendritic shaft
0.36	GO:0043197	dendritic spine
0.35	GO:0032279	asymmetric synapse
0.35	GO:0009986	cell surface

sp|P15387|KCNB1_RAT
Potassium voltage-gated channel subfamily B member 1
Search

KCNB1

0.94	Potassium voltage-gated channel subfamily B member 1

0.74	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0051260	protein homooligomerization
0.73	GO:0071805	potassium ion transmembrane transport
0.67	GO:1900454	positive regulation of long term synaptic depression
0.65	GO:0090314	positive regulation of protein targeting to membrane
0.64	GO:0046676	negative regulation of insulin secretion
0.64	GO:0098900	regulation of action potential
0.63	GO:0071333	cellular response to glucose stimulus
0.63	GO:0001508	action potential
0.49	GO:0010701	positive regulation of norepinephrine secretion

0.78	GO:0005249	voltage-gated potassium channel activity
0.61	GO:0044325	ion channel binding
0.43	GO:0046982	protein heterodimerization activity
0.38	GO:0047485	protein N-terminus binding
0.37	GO:0000149	SNARE binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.65	GO:0032809	neuronal cell body membrane
0.60	GO:0030425	dendrite
0.46	GO:0043204	perikaryon
0.46	GO:0016328	lateral plasma membrane
0.46	GO:0042383	sarcolemma
0.45	GO:0030424	axon
0.44	GO:0045211	postsynaptic membrane
0.43	GO:0030054	cell junction
0.38	GO:0032589	neuron projection membrane

sp|P15389|SCN5A_RAT
Sodium channel protein type 5 subunit alpha
Search

SCN5A

0.66	Sodium voltage-gated channel alpha subunit 5

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0035725	sodium ion transmembrane transport
0.54	GO:0001508	action potential
0.53	GO:0035637	multicellular organismal signaling
0.53	GO:0019233	sensory perception of pain
0.51	GO:0051899	membrane depolarization
0.49	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.47	GO:0055117	regulation of cardiac muscle contraction
0.47	GO:0002027	regulation of heart rate
0.44	GO:0007267	cell-cell signaling

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.72	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.47	GO:0044325	ion channel binding
0.40	GO:0050998	nitric-oxide synthase binding
0.40	GO:0030506	ankyrin binding
0.40	GO:0017134	fibroblast growth factor binding
0.40	GO:0097110	scaffold protein binding
0.38	GO:0031625	ubiquitin protein ligase binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.40	GO:0030315	T-tubule
0.40	GO:0014704	intercalated disc
0.40	GO:0016328	lateral plasma membrane
0.39	GO:0005901	caveola
0.39	GO:0030018	Z disc
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0009986	cell surface
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0044299	C-fiber

sp|P15390|SCN4A_RAT
Sodium channel protein type 4 subunit alpha
Search

SCN4A

0.57	Sodium channel protein type 4 subunit alpha

0.77	GO:0035725	sodium ion transmembrane transport
0.75	GO:0034765	regulation of ion transmembrane transport
0.53	GO:0019228	neuronal action potential
0.53	GO:0086010	membrane depolarization during action potential
0.37	GO:0015871	choline transport
0.37	GO:0006936	muscle contraction
0.37	GO:0006813	potassium ion transport
0.33	GO:0010469	regulation of receptor activity

0.84	GO:0005248	voltage-gated sodium channel activity
0.72	GO:0022832	voltage-gated channel activity
0.70	GO:0022839	ion gated channel activity
0.70	GO:0008381	mechanosensitive ion channel activity
0.39	GO:0005509	calcium ion binding
0.34	GO:0005267	potassium channel activity
0.33	GO:0005179	hormone activity

0.84	GO:0001518	voltage-gated sodium channel complex
0.34	GO:0008076	voltage-gated potassium channel complex
0.33	GO:0005576	extracellular region

sp|P15393|C11B1_RAT
Cytochrome P450 11B1, mitochondrial
Search

0.78	Cholesterol side-chain cleavage enzyme, mitochondrial

0.67	GO:0006700	C21-steroid hormone biosynthetic process
0.60	GO:0032341	aldosterone metabolic process
0.60	GO:0006705	mineralocorticoid biosynthetic process
0.59	GO:0008211	glucocorticoid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0008203	cholesterol metabolic process
0.51	GO:0046184	aldehyde biosynthetic process
0.50	GO:1901617	organic hydroxy compound biosynthetic process
0.50	GO:0042181	ketone biosynthetic process
0.50	GO:0002017	regulation of blood volume by renal aldosterone

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0008395	steroid hydroxylase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.37	GO:0008289	lipid binding
0.36	GO:0043178	alcohol binding
0.35	GO:0033293	monocarboxylic acid binding
0.34	GO:0019842	vitamin binding
0.32	GO:0005515	protein binding

0.54	GO:0005739	mitochondrion
0.47	GO:0031967	organelle envelope
0.47	GO:0031090	organelle membrane
0.36	GO:0036477	somatodendritic compartment
0.35	GO:0030176	integral component of endoplasmic reticulum membrane
0.35	GO:0043005	neuron projection
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0044297	cell body
0.33	GO:0070013	intracellular organelle lumen

0.68

GO:0016705

sp|P15399|PBAS_RAT
Probasin
Search

PBSN

0.97

Probasin

0.51

GO:0036094

small molecule binding

0.55	GO:0005576	extracellular region
0.42	GO:0005634	nucleus

sp|P15429|ENOB_RAT
Beta-enolase
Search

ENO3

0.83	Beta-enolase 3 transcript variant 1

0.71	GO:0006096	glycolytic process
0.39	GO:0061718	glucose catabolic process to pyruvate
0.39	GO:0006735	NADH regeneration
0.38	GO:0043403	skeletal muscle tissue regeneration
0.37	GO:0007568	aging
0.37	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.37	GO:0010756	positive regulation of plasminogen activation
0.37	GO:2001171	positive regulation of ATP biosynthetic process
0.37	GO:0021762	substantia nigra development
0.37	GO:0019319	hexose biosynthetic process

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.39	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0045296	cadherin binding
0.36	GO:0019899	enzyme binding
0.35	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0005212	structural constituent of eye lens

0.77	GO:0000015	phosphopyruvate hydratase complex
0.42	GO:0001917	photoreceptor inner segment
0.42	GO:0043204	perikaryon
0.42	GO:0005886	plasma membrane
0.42	GO:0043209	myelin sheath
0.37	GO:0044448	cell cortex part
0.37	GO:0070062	extracellular exosome
0.36	GO:0009986	cell surface
0.34	GO:0030426	growth cone
0.34	GO:0098857	membrane microdomain

0.78

EC:4.2.1.11

GO:0004634

sp|P15431|GBRB1_RAT
Gamma-aminobutyric acid receptor subunit beta-1
Search

GABRB1

0.89	Gamma-aminobutyric acid A receptor

0.59	GO:0007165	signal transduction
0.59	GO:0034220	ion transmembrane transport
0.51	GO:0006821	chloride transport
0.50	GO:0060384	innervation
0.50	GO:0090102	cochlea development
0.49	GO:0060119	inner ear receptor cell development
0.49	GO:0043524	negative regulation of neuron apoptotic process
0.48	GO:0007605	sensory perception of sound
0.46	GO:0071420	cellular response to histamine
0.41	GO:0032570	response to progesterone

0.82	GO:0004890	GABA-A receptor activity
0.74	GO:0005230	extracellular ligand-gated ion channel activity
0.55	GO:0099095	ligand-gated anion channel activity
0.52	GO:0005254	chloride channel activity
0.50	GO:0022835	transmitter-gated channel activity
0.41	GO:0050811	GABA receptor binding
0.32	GO:0003676	nucleic acid binding

0.60	GO:1902711	GABA-A receptor complex
0.55	GO:0005886	plasma membrane
0.42	GO:0034707	chloride channel complex
0.41	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.40	GO:0030425	dendrite
0.39	GO:0005635	nuclear envelope
0.36	GO:0031410	cytoplasmic vesicle
0.36	GO:0012506	vesicle membrane
0.36	GO:0070062	extracellular exosome

sp|P15473|IBP3_RAT
Insulin-like growth factor-binding protein 3
Search

IGFBP3

0.94	Insulin like growth factor binding protein 3

0.70	GO:0001558	regulation of cell growth
0.59	GO:0014912	negative regulation of smooth muscle cell migration
0.59	GO:0044342	type B pancreatic cell proliferation
0.58	GO:0045663	positive regulation of myoblast differentiation
0.58	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
0.58	GO:0048662	negative regulation of smooth muscle cell proliferation
0.56	GO:0001649	osteoblast differentiation
0.55	GO:0010906	regulation of glucose metabolic process
0.54	GO:0043666	regulation of phosphoprotein phosphatase activity
0.54	GO:0043065	positive regulation of apoptotic process

0.83	GO:0005520	insulin-like growth factor binding
0.60	GO:0008160	protein tyrosine phosphatase activator activity
0.58	GO:0001968	fibronectin binding
0.33	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.60	GO:0036454	growth factor complex
0.46	GO:0005634	nucleus
0.37	GO:0031091	platelet alpha granule
0.36	GO:0000792	heterochromatin
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044432	endoplasmic reticulum part

sp|P15589|STS_RAT
Steryl-sulfatase
Search

STS

0.93	Steroid sulfatase

0.39	GO:0007565	female pregnancy
0.38	GO:0008202	steroid metabolic process
0.36	GO:0043627	response to estrogen
0.36	GO:0009268	response to pH
0.36	GO:0043588	skin development
0.36	GO:0007611	learning or memory
0.36	GO:0043434	response to peptide hormone
0.35	GO:0008284	positive regulation of cell proliferation
0.35	GO:0014070	response to organic cyclic compound
0.35	GO:0006687	glycosphingolipid metabolic process

0.75	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005635	nuclear envelope
0.35	GO:0005794	Golgi apparatus
0.35	GO:0031982	vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0031090	organelle membrane
0.34	GO:0005764	lysosome
0.34	GO:0043230	extracellular organelle
0.33	GO:0005615	extracellular space
0.32	GO:0005886	plasma membrane

0.75

EC:3.1.6

GO:0008484

sp|P15650|ACADL_RAT
Long-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADL

0.96	Acyl-CoA dehydrogenase long chain

0.85	GO:0042758	long-chain fatty acid catabolic process
0.53	GO:0055114	oxidation-reduction process

0.86	GO:0004466	long-chain-acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding

0.30

GO:0031224

intrinsic component of membrane

0.86

EC:1.3.99.13

GO:0004466

sp|P15651|ACADS_RAT
Short-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADS

0.83	Mitochondrial short-chain specific acyl-CoA dehydrogenase

0.54	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.36	GO:0046359	butyrate catabolic process
0.35	GO:0051384	response to glucocorticoid
0.35	GO:0051289	protein homotetramerization
0.35	GO:0006508	proteolysis
0.34	GO:0042594	response to starvation

0.75	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.41	GO:0004085	butyryl-CoA dehydrogenase activity
0.36	GO:0008235	metalloexopeptidase activity
0.36	GO:0030145	manganese ion binding
0.36	GO:0004177	aminopeptidase activity
0.35	GO:0000062	fatty-acyl-CoA binding

0.48	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.33	GO:0031967	organelle envelope
0.33	GO:0031090	organelle membrane

0.75	EC:1.3.99.3	GO:0003995
0.41	KEGG:R01178	GO:0004085

sp|P15684|AMPN_RAT
Aminopeptidase N
Search

ANPEP

0.51	Aminopeptidase Ey

0.60	GO:0006508	proteolysis
0.48	GO:0008217	regulation of blood pressure
0.46	GO:0043171	peptide catabolic process
0.45	GO:0007267	cell-cell signaling
0.43	GO:0001525	angiogenesis
0.41	GO:0030154	cell differentiation
0.41	GO:0007165	signal transduction
0.38	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.38	GO:0044409	entry into host
0.37	GO:0019058	viral life cycle

0.70	GO:0004177	aminopeptidase activity
0.66	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.47	GO:0042277	peptide binding
0.42	GO:0104005	hijacked molecular function
0.33	GO:0004872	receptor activity

0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.54	GO:0070062	extracellular exosome
0.53	GO:0009897	external side of plasma membrane
0.41	GO:0005765	lysosomal membrane
0.36	GO:0012506	vesicle membrane
0.36	GO:0031983	vesicle lumen
0.35	GO:0030141	secretory granule
0.34	GO:0044433	cytoplasmic vesicle part
0.30	GO:0016021	integral component of membrane

0.70

EC:3.4.11

GO:0004177

sp|P15693|PPBI1_RAT
Intestinal-type alkaline phosphatase 1
Search

0.47	Intestinal-type alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.41	GO:0071773	cellular response to BMP stimulus
0.37	GO:0006501	C-terminal protein lipidation
0.37	GO:0009612	response to mechanical stimulus
0.35	GO:0036342	post-anal tail morphogenesis
0.35	GO:0035264	multicellular organism growth
0.35	GO:0021915	neural tube development
0.35	GO:0007586	digestion
0.35	GO:0006654	phosphatidic acid biosynthetic process
0.34	GO:0022008	neurogenesis

0.79	GO:0004035	alkaline phosphatase activity
0.45	GO:0002020	protease binding
0.39	GO:0000287	magnesium ion binding
0.39	GO:0008270	zinc ion binding
0.35	GO:0042803	protein homodimerization activity

0.43	GO:0009986	cell surface
0.42	GO:0031225	anchored component of membrane
0.41	GO:0005886	plasma membrane
0.39	GO:0098552	side of membrane
0.38	GO:0030016	myofibril
0.35	GO:0005903	brush border
0.35	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.79

EC:3.1.3.1

GO:0004035

sp|P15709|ST2A1_RAT
Bile salt sulfotransferase
Search

0.55	Bile salt sulfotransferase

0.55	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.53	GO:0008202	steroid metabolic process
0.49	GO:0006068	ethanol catabolic process
0.48	GO:0051923	sulfation
0.46	GO:0045606	positive regulation of epidermal cell differentiation
0.43	GO:0008285	negative regulation of cell proliferation
0.43	GO:1902652	secondary alcohol metabolic process
0.42	GO:0000103	sulfate assimilation
0.42	GO:0071305	cellular response to vitamin D
0.42	GO:0017085	response to insecticide

0.78	GO:0008146	sulfotransferase activity
0.46	GO:1990239	steroid hormone binding
0.44	GO:0015485	cholesterol binding
0.43	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.36	GO:0003676	nucleic acid binding
0.35	GO:0008144	drug binding
0.34	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.48	GO:0005829	cytosol
0.37	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0070062	extracellular exosome
0.35	GO:0012505	endomembrane system
0.32	GO:0005840	ribosome

0.78

GO:0008146

sp|P15725|TNR4_RAT
Tumor necrosis factor receptor superfamily member 4
Search

TNFRSF4

0.96	Tumor necrosis factor receptor superfamily member 4

0.60	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.58	GO:0032496	response to lipopolysaccharide
0.55	GO:0006954	inflammatory response
0.54	GO:0097190	apoptotic signaling pathway
0.54	GO:0002376	immune system process
0.53	GO:0042127	regulation of cell proliferation
0.53	GO:0042981	regulation of apoptotic process
0.51	GO:0007275	multicellular organism development
0.50	GO:0051047	positive regulation of secretion
0.50	GO:0051090	regulation of DNA binding transcription factor activity

0.62	GO:0005031	tumor necrosis factor-activated receptor activity
0.42	GO:0019955	cytokine binding
0.40	GO:0001618	virus receptor activity
0.32	GO:0046872	metal ion binding

0.50	GO:0009986	cell surface
0.49	GO:0005887	integral component of plasma membrane
0.46	GO:0098552	side of membrane
0.39	GO:0005829	cytosol

sp|P15791|KCC2D_RAT
Calcium/calmodulin-dependent protein kinase type II subunit delta
Search

CAMK2D

0.94	Calcium/calmodulin-dependent protein kinase type II subunit delta

0.63	GO:0006468	protein phosphorylation
0.44	GO:0018210	peptidyl-threonine modification
0.43	GO:0018209	peptidyl-serine modification
0.41	GO:0061049	cell growth involved in cardiac muscle cell development
0.41	GO:1901897	regulation of relaxation of cardiac muscle
0.41	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
0.41	GO:0035022	positive regulation of Rac protein signal transduction
0.41	GO:0010666	positive regulation of cardiac muscle cell apoptotic process
0.41	GO:0010649	regulation of cell communication by electrical coupling
0.41	GO:0055119	relaxation of cardiac muscle

0.81	GO:0004683	calmodulin-dependent protein kinase activity
0.78	GO:0005516	calmodulin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.41	GO:0050998	nitric-oxide synthase binding
0.40	GO:0044325	ion channel binding
0.36	GO:0031432	titin binding
0.36	GO:0019871	sodium channel inhibitor activity

0.41	GO:0043005	neuron projection
0.39	GO:0034704	calcium channel complex
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0033017	sarcoplasmic reticulum membrane
0.38	GO:0042383	sarcolemma
0.37	GO:0005829	cytosol
0.36	GO:0014704	intercalated disc
0.36	GO:0031594	neuromuscular junction
0.36	GO:0005634	nucleus
0.35	GO:0043025	neuronal cell body

0.81

EC:2.7.11.17

GO:0004683

sp|P15800|LAMB2_RAT
Laminin subunit beta-2
Search

LAMB2

0.86	Laminin subunit beta-2

0.87	GO:0072274	metanephric glomerular basement membrane development
0.87	GO:0048677	axon extension involved in regeneration
0.86	GO:0072313	metanephric glomerular epithelial cell development
0.86	GO:0072248	metanephric glomerular visceral epithelial cell differentiation
0.85	GO:0072015	glomerular visceral epithelial cell development
0.85	GO:0014002	astrocyte development
0.84	GO:0014044	Schwann cell development
0.82	GO:0007528	neuromuscular junction development
0.80	GO:0060041	retina development in camera-type eye
0.78	GO:0007411	axon guidance

0.82	GO:0005178	integrin binding
0.40	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.39	GO:0005198	structural molecule activity
0.33	GO:0043208	glycosphingolipid binding
0.32	GO:0019899	enzyme binding

0.86	GO:0005608	laminin-3 complex
0.85	GO:0043083	synaptic cleft
0.71	GO:0005615	extracellular space
0.47	GO:0043260	laminin-11 complex
0.43	GO:0005788	endoplasmic reticulum lumen
0.43	GO:1903561	extracellular vesicle
0.39	GO:0043257	laminin-8 complex
0.39	GO:0005607	laminin-2 complex
0.38	GO:0005606	laminin-1 complex
0.38	GO:0043259	laminin-10 complex

0.40

EC:3.4.19.12

GO:0036459

sp|P15823|ADA1B_RAT
Alpha-1B adrenergic receptor
Search

ADRA1B

0.97	Alpha-1B adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.82	GO:0055117	regulation of cardiac muscle contraction
0.82	GO:0019229	regulation of vasoconstriction
0.55	GO:0043410	positive regulation of MAPK cascade
0.52	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
0.50	GO:0045987	positive regulation of smooth muscle contraction
0.49	GO:1903524	positive regulation of blood circulation
0.49	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.48	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.48	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.86	GO:0004937	alpha1-adrenergic receptor activity
0.52	GO:0046982	protein heterodimerization activity

0.55	GO:0031965	nuclear membrane
0.55	GO:0005886	plasma membrane
0.40	GO:0045121	membrane raft
0.40	GO:0005737	cytoplasm
0.36	GO:0014704	intercalated disc
0.30	GO:0016021	integral component of membrane

sp|P15865|H14_RAT
Histone H1.4
Search

0.97	Histone cluster 1 H1 family member e

0.79	GO:0006334	nucleosome assembly
0.56	GO:0098532	histone H3-K27 trimethylation
0.55	GO:0080182	histone H3-K4 trimethylation
0.54	GO:0016584	nucleosome positioning
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0071169	establishment of protein localization to chromatin
0.46	GO:0051574	positive regulation of histone H3-K9 methylation
0.44	GO:0030307	positive regulation of cell growth
0.43	GO:0050821	protein stabilization
0.43	GO:0048260	positive regulation of receptor-mediated endocytosis

0.66	GO:0031490	chromatin DNA binding
0.45	GO:0042826	histone deacetylase binding
0.42	GO:0032564	dATP binding
0.42	GO:0008201	heparin binding
0.39	GO:0016208	AMP binding
0.38	GO:0043531	ADP binding
0.37	GO:0003690	double-stranded DNA binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0003723	RNA binding
0.36	GO:0032550	purine ribonucleoside binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.58	GO:0000791	euchromatin
0.55	GO:0031974	membrane-enclosed lumen
0.53	GO:0000792	heterochromatin
0.48	GO:0035327	transcriptionally active chromatin
0.41	GO:0031982	vesicle
0.40	GO:0009986	cell surface
0.38	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|P15887|ARRS_RAT
S-arrestin
Search

SAG

0.97	S-antigen visual arrestin

0.61	GO:0007165	signal transduction
0.38	GO:0031399	regulation of protein modification process
0.38	GO:0019220	regulation of phosphate metabolic process
0.37	GO:0007601	visual perception
0.36	GO:0006897	endocytosis
0.36	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.36	GO:0009416	response to light stimulus
0.35	GO:0010563	negative regulation of phosphorus metabolic process
0.35	GO:0032269	negative regulation of cellular protein metabolic process
0.35	GO:0071478	cellular response to radiation

0.60	GO:0002046	opsin binding
0.56	GO:0051219	phosphoprotein binding
0.37	GO:0030507	spectrin binding
0.35	GO:0042802	identical protein binding
0.35	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0004143	diacylglycerol kinase activity
0.34	GO:0043422	protein kinase B binding
0.34	GO:0003951	NAD+ kinase activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.58	GO:0001750	photoreceptor outer segment
0.57	GO:0001917	photoreceptor inner segment
0.37	GO:0045202	synapse
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.1.107	GO:0004143
0.34	KEGG:R00104	GO:0003951

sp|P15943|APLP2_RAT
Amyloid-like protein 2
Search

APLP2

0.87	Amyloid beta precursor like protein 2

0.73

GO:0010951

negative regulation of endopeptidase activity

0.82	GO:0008201	heparin binding
0.76	GO:0004867	serine-type endopeptidase inhibitor activity
0.58	GO:0046914	transition metal ion binding
0.54	GO:0042802	identical protein binding

0.48	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|P15950|KLK3_RAT
Glandular kallikrein-3, submandibular (Fragment)
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.41	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0007584	response to nutrient
0.39	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043065	positive regulation of apoptotic process
0.38	GO:0002778	antibacterial peptide production
0.38	GO:0008015	blood circulation
0.38	GO:0051604	protein maturation
0.37	GO:0009405	pathogenesis
0.36	GO:0072672	neutrophil extravasation

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.38	GO:0090729	toxin activity
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0005102	receptor binding
0.35	GO:0030545	receptor regulator activity
0.34	GO:0046872	metal ion binding
0.34	GO:0019899	enzyme binding
0.33	GO:0043395	heparan sulfate proteoglycan binding
0.33	GO:0008201	heparin binding

0.47	GO:0005615	extracellular space
0.42	GO:0030141	secretory granule
0.40	GO:1903561	extracellular vesicle
0.39	GO:0043234	protein complex
0.39	GO:0097223	sperm part
0.39	GO:0005634	nucleus
0.39	GO:0045177	apical part of cell
0.36	GO:0005766	primary lysosome
0.36	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P15978|HA11_RAT
Class I histocompatibility antigen, Non-RT1.A alpha-1 chain
Search

0.38	Major histocompatibility complex class I

0.73	GO:0048002	antigen processing and presentation of peptide antigen
0.66	GO:0006955	immune response
0.51	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.47	GO:0019883	antigen processing and presentation of endogenous antigen
0.45	GO:0051239	regulation of multicellular organismal process
0.45	GO:0007275	multicellular organism development
0.45	GO:0031345	negative regulation of cell projection organization
0.44	GO:0010721	negative regulation of cell development
0.44	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.44	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity

0.54	GO:0042605	peptide antigen binding
0.52	GO:0030881	beta-2-microglobulin binding
0.49	GO:0046977	TAP binding
0.48	GO:0042608	T cell receptor binding
0.39	GO:0046982	protein heterodimerization activity
0.37	GO:0046703	natural killer cell lectin-like receptor binding
0.36	GO:0042288	MHC class I protein binding

0.73	GO:0042612	MHC class I protein complex
0.47	GO:0009986	cell surface
0.46	GO:0070971	endoplasmic reticulum exit site
0.46	GO:0005797	Golgi medial cisterna
0.45	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.45	GO:0030670	phagocytic vesicle membrane
0.37	GO:0032398	MHC class Ib protein complex
0.37	GO:0045121	membrane raft
0.36	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle

sp|P15999|ATPA_RAT
ATP synthase subunit alpha, mitochondrial
Search

ATP5A1

0.45	ATP synthase subunit alpha

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.52	GO:0001937	negative regulation of endothelial cell proliferation
0.51	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.43	GO:0006629	lipid metabolic process
0.35	GO:0042407	cristae formation
0.34	GO:0006839	mitochondrial transport
0.33	GO:0046907	intracellular transport

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0043532	angiostatin binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0042288	MHC class I protein binding
0.34	GO:0003723	RNA binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0043209	myelin sheath
0.49	GO:0008180	COP9 signalosome
0.49	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.41	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0045121	membrane raft
0.34	GO:0005759	mitochondrial matrix

sp|P16036|MPCP_RAT
Phosphate carrier protein, mitochondrial
Search

SLC25A3

0.84	Mitochondrial inorganic phosphate carrier

0.45	GO:0006839	mitochondrial transport
0.45	GO:0035435	phosphate ion transmembrane transport
0.34	GO:1902600	hydrogen ion transmembrane transport

0.48	GO:0032403	protein complex binding
0.45	GO:0015114	phosphate ion transmembrane transporter activity
0.38	GO:0015317	phosphate:proton symporter activity

0.52	GO:0043209	myelin sheath
0.45	GO:0005743	mitochondrial inner membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

sp|P16067|ANPRB_RAT
Atrial natriuretic peptide receptor 2
Search

NPR2

0.56	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.64	GO:0007168	receptor guanylyl cyclase signaling pathway
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.61	GO:1900194	negative regulation of oocyte maturation
0.60	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.57	GO:0051447	negative regulation of meiotic cell cycle
0.56	GO:0060348	bone development
0.50	GO:0022414	reproductive process
0.45	GO:0060038	cardiac muscle cell proliferation

0.82	GO:0004383	guanylate cyclase activity
0.66	GO:0016941	natriuretic peptide receptor activity
0.63	GO:0004672	protein kinase activity
0.61	GO:0017046	peptide hormone binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.46	GO:0004016	adenylate cyclase activity
0.35	GO:0019901	protein kinase binding

0.48	GO:0005887	integral component of plasma membrane
0.48	GO:0008074	guanylate cyclase complex, soluble
0.40	GO:0043235	receptor complex

0.82

EC:4.6.1.2

GO:0004383

sp|P16086|SPTN1_RAT
Spectrin alpha chain, non-erythrocytic 1
Search

SPTAN1

0.96	Spectrin alpha chain, non-erythrocytic 1

0.42	GO:0051693	actin filament capping
0.38	GO:0043312	neutrophil degranulation
0.38	GO:0007010	cytoskeleton organization
0.37	GO:0046907	intracellular transport
0.37	GO:0007411	axon guidance
0.37	GO:0000165	MAPK cascade
0.37	GO:0071166	ribonucleoprotein complex localization
0.36	GO:0051028	mRNA transport
0.36	GO:0048193	Golgi vesicle transport
0.36	GO:0006405	RNA export from nucleus

0.70	GO:0005509	calcium ion binding
0.56	GO:0045296	cadherin binding
0.41	GO:0005516	calmodulin binding
0.41	GO:0030507	spectrin binding
0.40	GO:0003779	actin binding
0.38	GO:0046982	protein heterodimerization activity
0.38	GO:0047485	protein N-terminus binding
0.37	GO:0019905	syntaxin binding
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0005200	structural constituent of cytoskeleton

0.51	GO:0015630	microtubule cytoskeleton
0.44	GO:0043227	membrane-bounded organelle
0.42	GO:0032437	cuticular plate
0.41	GO:0005916	fascia adherens
0.41	GO:0033270	paranode region of axon
0.41	GO:0008091	spectrin
0.41	GO:0016328	lateral plasma membrane
0.40	GO:0030018	Z disc
0.40	GO:0043209	myelin sheath
0.40	GO:0043230	extracellular organelle

sp|P16177|NK3R_RAT
Neuromedin-K receptor
Search

TACR3

0.97	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.58	GO:1902093	positive regulation of flagellated sperm motility
0.41	GO:0070472	regulation of uterine smooth muscle contraction
0.39	GO:0043278	response to morphine
0.39	GO:0042053	regulation of dopamine metabolic process
0.39	GO:0010460	positive regulation of heart rate
0.39	GO:0045777	positive regulation of blood pressure
0.39	GO:0045987	positive regulation of smooth muscle contraction
0.39	GO:0042220	response to cocaine
0.39	GO:0060259	regulation of feeding behavior

0.86	GO:0004995	tachykinin receptor activity
0.35	GO:0050254	rhodopsin kinase activity
0.33	GO:0005515	protein binding

0.57	GO:0097225	sperm midpiece
0.56	GO:0005886	plasma membrane
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0031252	cell leading edge
0.36	GO:0061827	sperm head
0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.35

GO:0050254

sp|P16221|COX8B_RAT
Cytochrome c oxidase subunit 8B, mitochondrial
Search

0.95	Cytochrome c oxidase, subunit VIIIb

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.46	GO:0006119	oxidative phosphorylation
0.46	GO:0009060	aerobic respiration
0.39	GO:0042493	response to drug

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.56	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P16228|CATE_RAT
Cathepsin E
Search

CTSE

0.94	Cathepsin E-B

0.74	GO:0016540	protein autoprocessing
0.59	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.45	GO:0030163	protein catabolic process
0.44	GO:0007586	digestion
0.42	GO:0006914	autophagy
0.33	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.50	GO:0042803	protein homodimerization activity

0.52	GO:0005768	endosome
0.40	GO:0005576	extracellular region
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|P16232|DHI1_RAT
Corticosteroid 11-beta-dehydrogenase isozyme 1
Search

HSD11B1

0.97	Corticosteroid 11-beta-dehydrogenase isozyme 1

0.56	GO:0030324	lung development
0.52	GO:0055114	oxidation-reduction process
0.42	GO:0008202	steroid metabolic process
0.37	GO:0042445	hormone metabolic process
0.36	GO:0043456	regulation of pentose-phosphate shunt
0.36	GO:0071392	cellular response to estradiol stimulus
0.35	GO:0031667	response to nutrient levels
0.35	GO:0008610	lipid biosynthetic process
0.34	GO:0016042	lipid catabolic process
0.34	GO:1901361	organic cyclic compound catabolic process

0.62	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
0.48	GO:0070524	11-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.35	GO:0005496	steroid binding
0.34	GO:0050661	NADP binding
0.34	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.34	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.34	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

0.41	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0044428	nuclear part
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0045177	apical part of cell
0.34	GO:0031090	organelle membrane
0.33	GO:0031967	organelle envelope
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.48

EC:1.1.1.146

GO:0070524

sp|P16235|LSHR_RAT
Lutropin-choriogonadotropic hormone receptor
Search

LHCGR

0.95	Lutropin-choriogonadotropic hormone receptor

0.85	GO:0042700	luteinizing hormone signaling pathway
0.67	GO:0071371	cellular response to gonadotropin stimulus
0.67	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.67	GO:0046544	development of secondary male sexual characteristics
0.66	GO:0007190	activation of adenylate cyclase activity
0.64	GO:0090030	regulation of steroid hormone biosynthetic process
0.64	GO:0072520	seminiferous tubule development
0.64	GO:0008585	female gonad development
0.63	GO:0022602	ovulation cycle process
0.63	GO:0060065	uterus development

0.85	GO:0004964	luteinizing hormone receptor activity
0.68	GO:0035472	choriogonadotropin hormone receptor activity
0.68	GO:0038106	choriogonadotropin hormone binding
0.53	GO:0004963	follicle-stimulating hormone receptor activity
0.49	GO:0008528	G-protein coupled peptide receptor activity
0.37	GO:0017046	peptide hormone binding
0.37	GO:0051117	ATPase binding
0.36	GO:0042803	protein homodimerization activity

0.53	GO:0005886	plasma membrane
0.39	GO:0005622	intracellular
0.37	GO:0031982	vesicle
0.37	GO:0012505	endomembrane system
0.36	GO:0043235	receptor complex
0.36	GO:0009986	cell surface
0.36	GO:0098552	side of membrane
0.36	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P16257|TSPO_RAT
Translocator protein
Search

TSPO

0.93	Translocator protein isoform PBR (Fragment)

0.61	GO:0072656	maintenance of protein location in mitochondrion
0.60	GO:1903147	negative regulation of autophagy of mitochondrion
0.60	GO:1903579	negative regulation of ATP metabolic process
0.58	GO:0031397	negative regulation of protein ubiquitination
0.58	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.54	GO:0072655	establishment of protein localization to mitochondrion
0.44	GO:0060319	primitive erythrocyte differentiation
0.41	GO:0010266	response to vitamin B1
0.41	GO:0014012	peripheral nervous system axon regeneration
0.41	GO:0051901	positive regulation of mitochondrial depolarization

0.58	GO:0044325	ion channel binding
0.41	GO:0008503	benzodiazepine receptor activity
0.41	GO:0005497	androgen binding
0.37	GO:0015485	cholesterol binding
0.36	GO:0017127	cholesterol transporter activity

0.46	GO:0005739	mitochondrion
0.38	GO:0031968	organelle outer membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|P16259|CAN3_RAT
Calpain-3
Search

CAPN3

0.94	Calpain 3 transcription variant 10

0.85	GO:0045214	sarcomere organization
0.65	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration
0.63	GO:0033234	negative regulation of protein sumoylation
0.61	GO:0070315	G1 to G0 transition involved in cell differentiation
0.61	GO:0006508	proteolysis
0.60	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.60	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.59	GO:0071472	cellular response to salt stress
0.59	GO:0071277	cellular response to calcium ion
0.59	GO:2001015	negative regulation of skeletal muscle cell differentiation

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.69	GO:0005509	calcium ion binding
0.66	GO:0055103	ligase regulator activity
0.63	GO:0031432	titin binding
0.62	GO:0008307	structural constituent of muscle
0.58	GO:0032947	protein complex scaffold activity
0.58	GO:0031402	sodium ion binding
0.34	GO:0005102	receptor binding
0.34	GO:0019899	enzyme binding
0.34	GO:0004871	signal transducer activity

0.54	GO:0030315	T-tubule
0.53	GO:0030018	Z disc
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.46	GO:0043234	protein complex

sp|P16261|GDC_RAT
Graves disease carrier protein (Fragment)
Search

SLC25A16

0.89	Graves disease carrier protein homolog

0.54	GO:0055085	transmembrane transport
0.45	GO:0006839	mitochondrial transport
0.36	GO:0006264	mitochondrial DNA replication
0.36	GO:0043504	mitochondrial DNA repair
0.35	GO:0000729	DNA double-strand break processing
0.35	GO:0045740	positive regulation of DNA replication
0.35	GO:0000076	DNA replication checkpoint
0.35	GO:0043137	DNA replication, removal of RNA primer
0.34	GO:0009108	coenzyme biosynthetic process
0.34	GO:0006284	base-excision repair

0.39	GO:0022857	transmembrane transporter activity
0.36	GO:0016890	site-specific endodeoxyribonuclease activity, specific for altered base
0.35	GO:0043142	single-stranded DNA-dependent ATPase activity
0.35	GO:0017108	5'-flap endonuclease activity
0.35	GO:0043139	5'-3' DNA helicase activity
0.33	GO:0003677	DNA binding

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.35	GO:0005760	gamma DNA polymerase complex
0.35	GO:0042645	mitochondrial nucleoid
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.1.25

GO:0016890

sp|P16290|PGAM2_RAT
Phosphoglycerate mutase 2
Search

PGAM2

0.48	Phosphoglycerate mutase

0.69	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.66	GO:0019362	pyridine nucleotide metabolic process
0.55	GO:0043456	regulation of pentose-phosphate shunt
0.53	GO:0006941	striated muscle contraction
0.51	GO:0007219	Notch signaling pathway
0.47	GO:0019319	hexose biosynthetic process
0.47	GO:0006006	glucose metabolic process
0.41	GO:0045730	respiratory burst

0.83	GO:0004082	bisphosphoglycerate mutase activity
0.77	GO:0004619	phosphoglycerate mutase activity
0.39	GO:0019901	protein kinase binding
0.35	GO:0016787	hydrolase activity
0.34	GO:0048037	cofactor binding
0.33	GO:0034061	DNA polymerase activity
0.32	GO:0003677	DNA binding

0.46	GO:0005829	cytosol
0.45	GO:0043209	myelin sheath
0.38	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

0.83

EC:5.4.2.4

GO:0004082

sp|P16296|FA9_RAT
Coagulation factor IX
Search

0.85	Coagulation factor IXb

0.80	GO:0007596	blood coagulation
0.63	GO:0031638	zymogen activation
0.45	GO:0051897	positive regulation of protein kinase B signaling
0.36	GO:0017187	peptidyl-glutamic acid carboxylation
0.36	GO:0072376	protein activation cascade
0.35	GO:0006465	signal peptide processing
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0010952	positive regulation of peptidase activity
0.34	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.33	GO:0050927	positive regulation of positive chemotaxis

0.67	GO:0004252	serine-type endopeptidase activity
0.66	GO:0005509	calcium ion binding
0.42	GO:0005543	phospholipid binding
0.34	GO:0016504	peptidase activator activity
0.34	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0090729	toxin activity

0.63	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.36	GO:0005796	Golgi lumen
0.36	GO:0005788	endoplasmic reticulum lumen
0.34	GO:1905286	serine-type peptidase complex
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0004252

sp|P16303|CES1D_RAT
Carboxylesterase 1D
Search

0.53	Liver carboxylesterase

0.58	GO:0051791	medium-chain fatty acid metabolic process
0.58	GO:0034377	plasma lipoprotein particle assembly
0.56	GO:0006695	cholesterol biosynthetic process
0.53	GO:0030855	epithelial cell differentiation
0.53	GO:0019626	short-chain fatty acid catabolic process
0.53	GO:0046464	acylglycerol catabolic process
0.48	GO:0090122	cholesterol ester hydrolysis involved in cholesterol transport
0.47	GO:0090320	regulation of chylomicron remnant clearance
0.44	GO:0090207	regulation of triglyceride metabolic process
0.44	GO:0009636	response to toxic substance

0.70	GO:0052689	carboxylic ester hydrolase activity
0.51	GO:0016298	lipase activity
0.45	GO:0016290	palmitoyl-CoA hydrolase activity
0.42	GO:0019213	deacetylase activity

0.78	GO:0005788	endoplasmic reticulum lumen
0.54	GO:0005811	lipid droplet
0.50	GO:0005829	cytosol
0.41	GO:0005576	extracellular region

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

sp|P16310|GHR_RAT
Growth hormone receptor
Search

GHR

0.56	Growth hormone receptor

0.78	GO:0060396	growth hormone receptor signaling pathway
0.76	GO:0019221	cytokine-mediated signaling pathway
0.73	GO:0042976	activation of Janus kinase activity
0.71	GO:0048009	insulin-like growth factor receptor signaling pathway
0.71	GO:0043278	response to morphine
0.71	GO:0032094	response to food
0.70	GO:0046449	creatinine metabolic process
0.70	GO:0006600	creatine metabolic process
0.70	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.69	GO:0019530	taurine metabolic process

0.85	GO:0004903	growth hormone receptor activity
0.70	GO:0042169	SH2 domain binding
0.69	GO:0017046	peptide hormone binding
0.67	GO:0019903	protein phosphatase binding
0.66	GO:0019838	growth factor binding
0.63	GO:0019901	protein kinase binding
0.61	GO:0042803	protein homodimerization activity

0.77	GO:0070195	growth hormone receptor complex
0.70	GO:0036464	cytoplasmic ribonucleoprotein granule
0.66	GO:0005615	extracellular space
0.65	GO:0043025	neuronal cell body
0.62	GO:0005829	cytosol
0.61	GO:0009986	cell surface
0.61	GO:0019898	extrinsic component of membrane
0.56	GO:0005634	nucleus
0.55	GO:0005887	integral component of plasma membrane
0.51	GO:0005739	mitochondrion

sp|P16391|HA12_RAT
RT1 class I histocompatibility antigen, AA alpha chain
Search

0.33	Major histocompatibility complex class I

0.73	GO:0048002	antigen processing and presentation of peptide antigen
0.66	GO:0006955	immune response
0.52	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.48	GO:0019883	antigen processing and presentation of endogenous antigen
0.46	GO:0010977	negative regulation of neuron projection development
0.44	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.43	GO:0002655	regulation of tolerance induction to nonself antigen
0.43	GO:0002517	T cell tolerance induction
0.43	GO:0002654	positive regulation of tolerance induction dependent upon immune response
0.42	GO:0019884	antigen processing and presentation of exogenous antigen

0.53	GO:0042605	peptide antigen binding
0.51	GO:0030881	beta-2-microglobulin binding
0.48	GO:0046977	TAP binding
0.48	GO:0042608	T cell receptor binding
0.39	GO:0046982	protein heterodimerization activity
0.37	GO:0046703	natural killer cell lectin-like receptor binding
0.36	GO:0042288	MHC class I protein binding

0.73	GO:0042612	MHC class I protein complex
0.47	GO:0009986	cell surface
0.46	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.46	GO:0030670	phagocytic vesicle membrane
0.45	GO:0070971	endoplasmic reticulum exit site
0.45	GO:0005797	Golgi medial cisterna
0.37	GO:0045121	membrane raft
0.37	GO:0032398	MHC class Ib protein complex
0.36	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle

sp|P16409|MYL3_RAT
Myosin light chain 3
Search

MYL3

0.91	Myosin light chain 1, cardiac muscle

0.65	GO:0002026	regulation of the force of heart contraction
0.64	GO:0060048	cardiac muscle contraction
0.56	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.55	GO:0006942	regulation of striated muscle contraction
0.50	GO:0032781	positive regulation of ATPase activity
0.39	GO:0007519	skeletal muscle tissue development
0.37	GO:0030049	muscle filament sliding
0.34	GO:0060055	angiogenesis involved in wound healing
0.34	GO:0070527	platelet aggregation
0.34	GO:0007044	cell-substrate junction assembly

0.70	GO:0005509	calcium ion binding
0.63	GO:0003785	actin monomer binding
0.49	GO:0051015	actin filament binding
0.37	GO:0032038	myosin II heavy chain binding
0.37	GO:0003774	motor activity
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004872	receptor activity

0.64	GO:0031672	A band
0.55	GO:0031674	I band
0.42	GO:0016459	myosin complex
0.35	GO:0005829	cytosol
0.34	GO:0008305	integrin complex

0.33

GO:0004252

sp|P16443|DBP_RAT
D site-binding protein
Search

0.93	D-box binding PAR bZIP transcription factor

0.72	GO:0007623	circadian rhythm
0.71	GO:0006366	transcription by RNA polymerase II
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.62	GO:0035914	skeletal muscle cell differentiation

0.76	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.71	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.70	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61

GO:0005634

nucleus

sp|P16446|PIPNA_RAT
Phosphatidylinositol transfer protein alpha isoform
Search

PITPNA

0.96	Phosphatidylinositol transfer protein alpha

0.77	GO:0015914	phospholipid transport
0.52	GO:0007409	axonogenesis
0.36	GO:0043009	chordate embryonic development
0.36	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0035845	photoreceptor cell outer segment organization
0.34	GO:0007601	visual perception
0.33	GO:0006629	lipid metabolic process

0.78	GO:0005548	phospholipid transporter activity
0.56	GO:0031210	phosphatidylcholine binding
0.50	GO:0035091	phosphatidylinositol binding
0.36	GO:0070540	stearic acid binding
0.35	GO:1901611	phosphatidylglycerol binding
0.35	GO:0000062	fatty-acyl-CoA binding

0.52	GO:0043209	myelin sheath
0.44	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.36	GO:0012505	endomembrane system
0.34	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|P16453|DCHS_RAT
Histidine decarboxylase
Search

HDC

0.80	Histidine decarboxylase

0.60	GO:0001694	histamine biosynthetic process
0.60	GO:0006520	cellular amino acid metabolic process
0.52	GO:0052805	imidazole-containing compound catabolic process
0.47	GO:0046395	carboxylic acid catabolic process
0.43	GO:0009628	response to abiotic stimulus
0.42	GO:0042330	taxis
0.42	GO:0007409	axonogenesis
0.41	GO:0007420	brain development
0.41	GO:0007268	chemical synaptic transmission
0.41	GO:0042423	catecholamine biosynthetic process

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.35	GO:0016597	amino acid binding
0.35	GO:0042803	protein homodimerization activity
0.32	GO:0016874	ligase activity

0.35	GO:0005829	cytosol
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite

0.68

EC:4.1.1

GO:0016831

sp|P16573|CEAM1_RAT
Carcinoembryonic antigen-related cell adhesion molecule 1
Search

0.85	Pregnancy-specific beta-1-glycoprotein 8

0.52	GO:0043317	regulation of cytotoxic T cell degranulation
0.51	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.50	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.49	GO:0043301	negative regulation of leukocyte degranulation
0.49	GO:0050860	negative regulation of T cell receptor signaling pathway
0.48	GO:0044319	wound healing, spreading of cells
0.47	GO:0050868	negative regulation of T cell activation
0.47	GO:2000346	negative regulation of hepatocyte proliferation
0.47	GO:0038016	insulin receptor internalization
0.47	GO:1903385	regulation of homophilic cell adhesion

0.50	GO:0031005	filamin binding
0.49	GO:1990782	protein tyrosine kinase binding
0.48	GO:0019903	protein phosphatase binding
0.46	GO:0042803	protein homodimerization activity
0.46	GO:0015125	bile acid transmembrane transporter activity
0.45	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.45	GO:0003779	actin binding
0.44	GO:0046790	virion binding
0.44	GO:0035325	Toll-like receptor binding
0.44	GO:0001618	virus receptor activity

0.50	GO:0042101	T cell receptor complex
0.47	GO:0005615	extracellular space
0.47	GO:0009986	cell surface
0.46	GO:0005911	cell-cell junction
0.46	GO:0031528	microvillus membrane
0.45	GO:0009925	basal plasma membrane
0.45	GO:0016328	lateral plasma membrane
0.44	GO:0016324	apical plasma membrane
0.44	GO:0031982	vesicle
0.43	GO:0043230	extracellular organelle

sp|P16598|IL1A_RAT
Interleukin-1 alpha
Search

IL1A

0.82	Interleukin-1 alpha

0.86	GO:0001660	fever generation
0.83	GO:0051781	positive regulation of cell division
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.65	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.65	GO:2000391	positive regulation of neutrophil extravasation
0.64	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.64	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.64	GO:0046688	response to copper ion
0.64	GO:0035234	ectopic germ cell programmed cell death

0.86	GO:0005149	interleukin-1 receptor binding
0.80	GO:0005125	cytokine activity
0.58	GO:0005507	copper ion binding

0.73	GO:0005615	extracellular space
0.68	GO:0005829	cytosol
0.37	GO:0009986	cell surface
0.34	GO:0005886	plasma membrane

sp|P16599|TNFA_RAT
Tumor necrosis factor
Search

TNF

0.93	Tumor necrosis factor-alpha

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.71	GO:0097527	necroptotic signaling pathway
0.61	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.61	GO:0043507	positive regulation of JUN kinase activity
0.60	GO:0061048	negative regulation of branching involved in lung morphogenesis
0.60	GO:1904999	positive regulation of leukocyte adhesion to arterial endothelial cell
0.60	GO:0045994	positive regulation of translational initiation by iron
0.60	GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus
0.60	GO:2000332	regulation of blood microparticle formation

0.84	GO:0005164	tumor necrosis factor receptor binding
0.80	GO:0005125	cytokine activity
0.55	GO:0002020	protease binding
0.51	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0042802	identical protein binding

0.73	GO:0005615	extracellular space
0.57	GO:0001891	phagocytic cup
0.55	GO:0055037	recycling endosome
0.54	GO:0009897	external side of plasma membrane
0.53	GO:0098857	membrane microdomain
0.47	GO:0005887	integral component of plasma membrane
0.35	GO:0030141	secretory granule

sp|P16610|NK2R_RAT
Substance-K receptor
Search

TACR2

0.92	Substance-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.66	GO:1902093	positive regulation of flagellated sperm motility
0.63	GO:0070472	regulation of uterine smooth muscle contraction
0.51	GO:0045987	positive regulation of smooth muscle contraction
0.46	GO:0048265	response to pain
0.46	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.45	GO:0007267	cell-cell signaling
0.43	GO:0035106	operant conditioning
0.43	GO:0032224	positive regulation of synaptic transmission, cholinergic
0.43	GO:0043117	positive regulation of vascular permeability

0.86	GO:0004995	tachykinin receptor activity
0.34	GO:0005515	protein binding
0.34	GO:0050254	rhodopsin kinase activity

0.65	GO:0097225	sperm midpiece
0.63	GO:0061827	sperm head
0.56	GO:0005886	plasma membrane
0.38	GO:0030425	dendrite
0.38	GO:0044297	cell body
0.36	GO:0031252	cell leading edge
0.35	GO:0009986	cell surface
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34