Queries 20001 to 20141

Query header

Description
Estimated PPV, description

Biological process
Estimated PPV, GO-id, description

Molecular function
Estimated PPV, GO-i d, description

Cellular component
Estimated PPV, GO-id, description

Inverse ec2go, kegg2go

sp|Q95153|BRCA1_CANLF
Breast cancer type 1 susceptibility protein homolog
Search

BRCA1

0.91	Breast cancer type 1 susceptibility protein homolog

0.81	GO:0085020	protein K6-linked ubiquitination
0.76	GO:0051865	protein autoubiquitination
0.64	GO:0006281	DNA repair
0.61	GO:0007049	cell cycle
0.59	GO:0006310	DNA recombination
0.57	GO:0009048	dosage compensation by inactivation of X chromosome
0.55	GO:0045717	negative regulation of fatty acid biosynthetic process
0.55	GO:0035067	negative regulation of histone acetylation
0.55	GO:0071158	positive regulation of cell cycle arrest
0.55	GO:0035066	positive regulation of histone acetylation

0.72	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0001105	RNA polymerase II transcription coactivator activity
0.54	GO:0003677	DNA binding
0.51	GO:0070063	RNA polymerase binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0003723	RNA binding
0.37	GO:0015631	tubulin binding
0.36	GO:0050681	androgen receptor binding

0.79	GO:0031436	BRCA1-BARD1 complex
0.61	GO:0005694	chromosome
0.54	GO:0070531	BRCA1-A complex
0.44	GO:0031981	nuclear lumen
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0005886	plasma membrane
0.39	GO:0008274	gamma-tubulin ring complex

0.72

KEGG:R03876

GO:0004842

sp|Q95154|OLF1_CANLF
Olfactory receptor-like protein OLF1
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007283	spermatogenesis

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.51	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q95155|OLF2_CANLF
Olfactory receptor-like protein OLF2
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.55	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q95156|OLF3_CANLF
Olfactory receptor-like protein OLF3
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005549	odorant binding
0.32	GO:0003677	DNA binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q95157|OLF4_CANLF
Olfactory receptor-like protein OLF4
Search

0.45	Olfactory receptor

0.73	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.68	GO:0007186	G-protein coupled receptor signaling pathway

0.73	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q95158|GBGT1_CANLF
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
Search

GBGT1

0.95	Ral guanine nucleotide dissociation stimulator

0.60	GO:0005975	carbohydrate metabolic process
0.46	GO:0030259	lipid glycosylation
0.45	GO:0009247	glycolipid biosynthetic process
0.38	GO:0006486	protein glycosylation
0.33	GO:0006687	glycosphingolipid metabolic process
0.33	GO:0030148	sphingolipid biosynthetic process
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0065009	regulation of molecular function

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.47	GO:0008194	UDP-glycosyltransferase activity
0.36	GO:0140103	catalytic activity, acting on a glycoprotein
0.35	GO:0046872	metal ion binding
0.34	GO:0003823	antigen binding
0.33	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0005515	protein binding
0.32	GO:0098772	molecular function regulator
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.44	GO:0031982	vesicle
0.44	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.33	GO:0016592	mediator complex
0.33	GO:0005903	brush border
0.32	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.69

EC:2.4.1

GO:0016758

sp|Q95165|SCNNB_CANLF
Amiloride-sensitive sodium channel subunit beta
Search

SCNN1B

0.96	Amiloride-sensitive sodium channel subunit gamma

0.77	GO:0035725	sodium ion transmembrane transport
0.68	GO:0055078	sodium ion homeostasis
0.67	GO:0050891	multicellular organismal water homeostasis
0.47	GO:0050909	sensory perception of taste
0.39	GO:0050896	response to stimulus
0.38	GO:0007588	excretion
0.38	GO:0090504	epiboly
0.36	GO:0016477	cell migration
0.36	GO:0002028	regulation of sodium ion transport

0.85	GO:0015280	ligand-gated sodium channel activity
0.68	GO:0050699	WW domain binding

0.66	GO:0034706	sodium channel complex
0.63	GO:0009897	external side of plasma membrane
0.63	GO:0070062	extracellular exosome
0.54	GO:0005887	integral component of plasma membrane
0.48	GO:0016324	apical plasma membrane
0.45	GO:0030659	cytoplasmic vesicle membrane
0.41	GO:0005654	nucleoplasm

sp|Q95167|KCNB2_CANLF
Potassium voltage-gated channel subfamily B member 2 (Fragment)
Search

KCNB2

0.93	LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily B member 1

0.73	GO:0071805	potassium ion transmembrane transport
0.72	GO:0051260	protein homooligomerization
0.72	GO:0034765	regulation of ion transmembrane transport
0.45	GO:0072659	protein localization to plasma membrane
0.42	GO:0021591	ventricular system development
0.42	GO:0090504	epiboly
0.40	GO:1900454	positive regulation of long term synaptic depression
0.40	GO:0090314	positive regulation of protein targeting to membrane
0.40	GO:0046676	negative regulation of insulin secretion
0.39	GO:0098900	regulation of action potential

0.78	GO:0005249	voltage-gated potassium channel activity
0.42	GO:0046982	protein heterodimerization activity
0.41	GO:0044325	ion channel binding
0.35	GO:0047485	protein N-terminus binding
0.35	GO:0000149	SNARE binding
0.34	GO:0042162	telomeric DNA binding
0.34	GO:0042803	protein homodimerization activity

0.78	GO:0008076	voltage-gated potassium channel complex
0.48	GO:0032809	neuronal cell body membrane
0.46	GO:0043204	perikaryon
0.45	GO:0030425	dendrite
0.37	GO:0016328	lateral plasma membrane
0.37	GO:0042383	sarcolemma
0.36	GO:0030424	axon
0.36	GO:0045211	postsynaptic membrane
0.36	GO:0030054	cell junction
0.35	GO:0044214	spanning component of plasma membrane

sp|Q95168|ZO2_CANLF
Tight junction protein ZO-2
Search

TJP2

0.95	LOW QUALITY PROTEIN: tight junction protein ZO-2

0.56	GO:0090557	establishment of endothelial intestinal barrier
0.56	GO:2001205	negative regulation of osteoclast development
0.55	GO:0071847	TNFSF11-mediated signaling pathway
0.55	GO:0050892	intestinal absorption
0.53	GO:0090559	regulation of membrane permeability
0.36	GO:0016226	iron-sulfur cluster assembly
0.35	GO:0035329	hippo signaling
0.35	GO:0046710	GDP metabolic process
0.35	GO:0046037	GMP metabolic process
0.32	GO:0055114	oxidation-reduction process

0.52	GO:0045296	cadherin binding
0.51	GO:0030674	protein binding, bridging
0.50	GO:0019904	protein domain specific binding
0.39	GO:0008022	protein C-terminus binding
0.36	GO:0008199	ferric iron binding
0.35	GO:0004385	guanylate kinase activity
0.34	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor

0.80	GO:0005923	bicellular tight junction
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.36	GO:0009986	cell surface
0.35	GO:0005921	gap junction
0.35	GO:0005912	adherens junction
0.33	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.35

EC:2.7.4.8

GO:0004385

sp|Q95J76|IL5_CANLF
Interleukin-5
Search

IL5

0.97	Interleukin-5

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.70	GO:0051024	positive regulation of immunoglobulin secretion
0.69	GO:0071803	positive regulation of podosome assembly
0.65	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.64	GO:0051091	positive regulation of DNA binding transcription factor activity
0.58	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0045645	positive regulation of eosinophil differentiation
0.43	GO:0030890	positive regulation of B cell proliferation
0.43	GO:0046427	positive regulation of JAK-STAT cascade

0.87	GO:0005137	interleukin-5 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity

0.73	GO:0005615	extracellular space
0.32	GO:0005622	intracellular

0.36

EC:2.7.10

GO:0004713

sp|Q95JD5|ST1B1_CANLF
Sulfotransferase family cytosolic 1B member 1
Search

0.55	Sulfotransferase

0.70	GO:0042403	thyroid hormone metabolic process
0.67	GO:0051923	sulfation
0.63	GO:0006805	xenobiotic metabolic process
0.56	GO:0006068	ethanol catabolic process
0.56	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.53	GO:0009812	flavonoid metabolic process
0.49	GO:0030855	epithelial cell differentiation
0.43	GO:0008202	steroid metabolic process
0.40	GO:0006584	catecholamine metabolic process
0.36	GO:0034754	cellular hormone metabolic process

0.78	GO:0008146	sulfotransferase activity
0.36	GO:0005515	protein binding
0.35	GO:0043199	sulfate binding
0.34	GO:0005496	steroid binding

0.39	GO:0005829	cytosol
0.35	GO:0031965	nuclear membrane

0.78

EC:2.8.2

GO:0008146

sp|Q95KM5|CLD3_CANLF
Claudin-3
Search

CLDN3

0.69

Claudin c

0.57	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.57	GO:0045216	cell-cell junction organization
0.54	GO:0070293	renal absorption
0.53	GO:0003382	epithelial cell morphogenesis
0.53	GO:0051291	protein heterooligomerization
0.53	GO:0061436	establishment of skin barrier
0.52	GO:0034329	cell junction assembly
0.51	GO:0001666	response to hypoxia
0.50	GO:0051260	protein homooligomerization
0.49	GO:1902476	chloride transmembrane transport

0.62	GO:0005198	structural molecule activity
0.49	GO:0042802	identical protein binding
0.49	GO:0005254	chloride channel activity
0.48	GO:0104005	hijacked molecular function
0.35	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0016787	hydrolase activity

0.81	GO:0005923	bicellular tight junction
0.65	GO:0016327	apicolateral plasma membrane
0.56	GO:0016328	lateral plasma membrane
0.45	GO:0005887	integral component of plasma membrane
0.40	GO:0045178	basal part of cell
0.39	GO:0045177	apical part of cell
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0034707	chloride channel complex
0.37	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle

0.32

EC:3

GO:0016787

sp|Q95KM6|CLD2_CANLF
Claudin-2
Search

CLDN2

0.69

Claudin

0.64	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.33	GO:0006461	protein complex assembly

0.62	GO:0005198	structural molecule activity
0.54	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|Q95KN1|CLUL1_CANLF
Clusterin-like protein 1
Search

CLUL1

0.94

Clusterin

sp|Q95LA1|FMO3_CANLF
Dimethylaniline monooxygenase [N-oxide-forming] 3
Search

FMO3

0.60	Flavin-containing monooxygenase

0.52	GO:0055114	oxidation-reduction process
0.41	GO:0042737	drug catabolic process
0.40	GO:0006739	NADP metabolic process
0.39	GO:0009404	toxin metabolic process
0.36	GO:0006805	xenobiotic metabolic process
0.36	GO:0006082	organic acid metabolic process
0.35	GO:0032496	response to lipopolysaccharide
0.35	GO:0006970	response to osmotic stress
0.35	GO:0072592	oxygen metabolic process

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.70	GO:0050661	NADP binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.46	GO:0034899	trimethylamine monooxygenase activity
0.34	GO:0016597	amino acid binding
0.34	GO:0005515	protein binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.14.13.8	GO:0004499
0.46	KEGG:R05623	GO:0034899

sp|Q95LA2|FMO1_CANLF
Dimethylaniline monooxygenase [N-oxide-forming] 1
Search

FMO1

0.60	Flavin-containing monooxygenase

0.62	GO:0070995	NADPH oxidation
0.51	GO:0009404	toxin metabolic process
0.46	GO:0017144	drug metabolic process
0.43	GO:0006082	organic acid metabolic process
0.40	GO:0006805	xenobiotic metabolic process
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:0006970	response to osmotic stress
0.38	GO:0044248	cellular catabolic process

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.70	GO:0050661	NADP binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0034899	trimethylamine monooxygenase activity
0.33	GO:0005515	protein binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.78	EC:1.14.13.8	GO:0004499
0.37	KEGG:R05623	GO:0034899

sp|Q95LF0|I13R2_CANLF
Interleukin-13 receptor subunit alpha-2
Search

IL13RA2

0.96	Interleukin-13 receptor subunit alpha-2

0.75	GO:0019221	cytokine-mediated signaling pathway
0.71	GO:0043305	negative regulation of mast cell degranulation
0.70	GO:0002638	negative regulation of immunoglobulin production
0.66	GO:0016064	immunoglobulin mediated immune response
0.38	GO:0071260	cellular response to mechanical stimulus

0.77	GO:0004896	cytokine receptor activity
0.35	GO:0005515	protein binding

0.38	GO:0005576	extracellular region
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q95MM9|SLAF1_CANLF
Signaling lymphocytic activation molecule
Search

SLAMF1

0.97	Signaling lymphocyte activation molecule SLAM

0.81	GO:0046649	lymphocyte activation
0.61	GO:0002232	leukocyte chemotaxis involved in inflammatory response
0.61	GO:1902714	negative regulation of interferon-gamma secretion
0.61	GO:0035744	T-helper 1 cell cytokine production
0.60	GO:1902715	positive regulation of interferon-gamma secretion
0.60	GO:0002725	negative regulation of T cell cytokine production
0.60	GO:2000510	positive regulation of dendritic cell chemotaxis
0.60	GO:0010759	positive regulation of macrophage chemotaxis
0.59	GO:0042104	positive regulation of activated T cell proliferation
0.57	GO:0032943	mononuclear cell proliferation

0.64	GO:0004872	receptor activity
0.52	GO:0042802	identical protein binding
0.36	GO:0001618	virus receptor activity
0.36	GO:0003823	antigen binding
0.34	GO:0004871	signal transducer activity

0.75	GO:0009986	cell surface
0.56	GO:0045335	phagocytic vesicle
0.52	GO:0098552	side of membrane
0.46	GO:0044459	plasma membrane part
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q95MP7|FRIH_CANLF
Ferritin heavy chain
Search

FTH1

0.53	Ferritin heavy chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.50	GO:0051238	sequestering of metal ion
0.47	GO:0051651	maintenance of location in cell
0.44	GO:0008285	negative regulation of cell proliferation
0.42	GO:0006955	immune response
0.40	GO:0048145	regulation of fibroblast proliferation
0.38	GO:0055114	oxidation-reduction process
0.35	GO:0060547	negative regulation of necrotic cell death
0.35	GO:0002446	neutrophil mediated immunity

0.76	GO:0008199	ferric iron binding
0.46	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.35	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding

0.40	GO:0044754	autolysosome
0.36	GO:0005739	mitochondrion
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0070288	ferritin complex
0.35	GO:0005615	extracellular space
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0044446	intracellular organelle part

0.46

EC:1.16.3

GO:0016724

sp|Q95N01|CCL17_CANLF
C-C motif chemokine 17
Search

CCL17

0.69	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.71	GO:0045662	negative regulation of myoblast differentiation
0.71	GO:0010469	regulation of receptor activity
0.56	GO:0071674	mononuclear cell migration
0.55	GO:0072676	lymphocyte migration
0.55	GO:1990266	neutrophil migration
0.54	GO:0071347	cellular response to interleukin-1
0.54	GO:0071356	cellular response to tumor necrosis factor
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0008009	chemokine activity
0.57	GO:0048020	CCR chemokine receptor binding

0.69

GO:0005615

extracellular space

tr|Q95N05|Q95N05_CANLF
Carboxylic ester hydrolase
Search

0.52	Liver carboxylesterase

0.58	GO:0051791	medium-chain fatty acid metabolic process
0.57	GO:0034377	plasma lipoprotein particle assembly
0.56	GO:0006695	cholesterol biosynthetic process
0.53	GO:0030855	epithelial cell differentiation
0.52	GO:0046464	acylglycerol catabolic process
0.49	GO:0090122	cholesterol ester hydrolysis involved in cholesterol transport
0.49	GO:0019626	short-chain fatty acid catabolic process
0.48	GO:0090320	regulation of chylomicron remnant clearance
0.45	GO:0090207	regulation of triglyceride metabolic process
0.44	GO:0009636	response to toxic substance

0.70	GO:0052689	carboxylic ester hydrolase activity
0.51	GO:0016298	lipase activity
0.46	GO:0016290	palmitoyl-CoA hydrolase activity
0.42	GO:0019213	deacetylase activity

0.79	GO:0005788	endoplasmic reticulum lumen
0.50	GO:0005811	lipid droplet
0.48	GO:0005829	cytosol
0.41	GO:0005576	extracellular region

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

sp|Q95N78|PPARA_CANLF
Peroxisome proliferator-activated receptor alpha
Search

PPARA

0.96	Peroxisome proliferator-activated receptor alpha

0.78	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
0.59	GO:0072363	regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
0.58	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
0.58	GO:0010887	negative regulation of cholesterol storage
0.58	GO:0010871	negative regulation of receptor biosynthetic process
0.58	GO:0010891	negative regulation of sequestering of triglyceride
0.58	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.57	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II

0.80	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.56	GO:0001103	RNA polymerase II repressing transcription factor binding
0.56	GO:0031624	ubiquitin conjugating enzyme binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.53	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding

0.60	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part

sp|Q9BDP4|VA0E1_CANLF
V-type proton ATPase subunit e 1
Search

ATP6V0E1

0.67	V-type proton ATPase subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.37	GO:0090383	phagosome acidification
0.37	GO:0010243	response to organonitrogen compound
0.37	GO:0033572	transferrin transport
0.36	GO:0007035	vacuolar acidification
0.36	GO:0016241	regulation of macroautophagy
0.36	GO:1901700	response to oxygen-containing compound
0.36	GO:1901699	cellular response to nitrogen compound
0.36	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.35	GO:0032870	cellular response to hormone stimulus

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.56	GO:0036442	proton-exporting ATPase activity
0.51	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.33	GO:0046983	protein dimerization activity
0.32	GO:0003676	nucleic acid binding

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.37	GO:0030670	phagocytic vesicle membrane
0.36	GO:0010008	endosome membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|Q9BDQ4|Q9BDQ4_CANLF
B2 bradykinin receptor
Search

BDKRB2

0.97	Bradykinin receptor, beta 2

0.80	GO:0006939	smooth muscle contraction
0.79	GO:0042310	vasoconstriction
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:1902238	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
0.60	GO:0006950	response to stress
0.60	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.59	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.58	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.58	GO:0042311	vasodilation
0.56	GO:0050482	arachidonic acid secretion

0.86	GO:0004947	bradykinin receptor activity
0.62	GO:0031702	type 1 angiotensin receptor binding
0.58	GO:0002020	protease binding
0.52	GO:0046982	protein heterodimerization activity
0.40	GO:0008188	neuropeptide receptor activity
0.39	GO:0042277	peptide binding
0.38	GO:0042562	hormone binding
0.36	GO:0004945	angiotensin type II receptor activity
0.36	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity

0.53	GO:0005768	endosome
0.44	GO:0005886	plasma membrane
0.37	GO:0097730	non-motile cilium
0.34	GO:0043005	neuron projection
0.33	GO:0045095	keratin filament
0.32	GO:0005802	trans-Golgi network
0.32	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0030659	cytoplasmic vesicle membrane
0.32	GO:0005635	nuclear envelope
0.32	GO:0005783	endoplasmic reticulum

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|Q9BDQ5|BKRB1_CANLF
B1 bradykinin receptor
Search

BDKRB1

0.97	Bradykinin receptor, beta 1

0.75	GO:0009612	response to mechanical stimulus
0.73	GO:0006954	inflammatory response
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0032496	response to lipopolysaccharide
0.46	GO:0003008	system process
0.45	GO:0002685	regulation of leukocyte migration
0.44	GO:0007602	phototransduction
0.44	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.44	GO:2000147	positive regulation of cell motility
0.43	GO:0051928	positive regulation of calcium ion transport

0.82	GO:0004947	bradykinin receptor activity
0.56	GO:0042277	peptide binding
0.44	GO:0009881	photoreceptor activity
0.39	GO:0004950	chemokine receptor activity
0.39	GO:0004875	complement receptor activity
0.37	GO:0019957	C-C chemokine binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0001847	opsonin receptor activity
0.32	GO:0004935	adrenergic receptor activity

0.43	GO:0043005	neuron projection
0.42	GO:0005886	plasma membrane
0.37	GO:0005654	nucleoplasm
0.35	GO:0009986	cell surface
0.35	GO:0098552	side of membrane
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0097225	sperm midpiece
0.34	GO:0097228	sperm principal piece
0.33	GO:0035579	specific granule membrane
0.33	GO:0035577	azurophil granule membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|Q9BDX4|IL3_CANLF
Interleukin-3
Search

0.64	Interleukin-3

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.69	GO:0001660	fever generation
0.62	GO:0019221	cytokine-mediated signaling pathway
0.59	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.56	GO:0008284	positive regulation of cell proliferation

0.88	GO:0005135	interleukin-3 receptor binding
0.78	GO:0008083	growth factor activity
0.67	GO:0005149	interleukin-1 receptor binding
0.62	GO:0005125	cytokine activity

0.66

GO:0005576

extracellular region

sp|Q9BEA0|EGF_CANLF
Pro-epidermal growth factor
Search

EGF

0.97	Pro-epidermal growth factor

0.72	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification
0.66	GO:0060070	canonical Wnt signaling pathway
0.62	GO:0010469	regulation of receptor activity
0.60	GO:0007262	STAT protein import into nucleus
0.59	GO:1900127	positive regulation of hyaluronan biosynthetic process
0.59	GO:0090370	negative regulation of cholesterol efflux
0.58	GO:0035413	positive regulation of catenin import into nucleus
0.58	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation
0.57	GO:0070371	ERK1 and ERK2 cascade
0.57	GO:0002092	positive regulation of receptor internalization

0.70	GO:0005509	calcium ion binding
0.68	GO:0017147	Wnt-protein binding
0.67	GO:0042813	Wnt-activated receptor activity
0.64	GO:0008083	growth factor activity
0.56	GO:0005154	epidermal growth factor receptor binding
0.38	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.38	GO:0004713	protein tyrosine kinase activity
0.38	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.33	GO:0009881	photoreceptor activity

0.63	GO:0043235	receptor complex
0.54	GO:0070062	extracellular exosome
0.43	GO:0005886	plasma membrane
0.39	GO:0005765	lysosomal membrane
0.38	GO:0031093	platelet alpha granule lumen
0.37	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0031429	box H/ACA snoRNP complex
0.32	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016021	integral component of membrane

0.38	EC:2.7.10	GO:0004713
0.38	KEGG:R04545	GO:0046934

sp|Q9BEF8|GHRL_CANLF
Appetite-regulating hormone
Search

GHRL

0.97	Ghrelin and obestatin prepropeptide

0.76	GO:0010469	regulation of receptor activity
0.64	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process
0.64	GO:0032097	positive regulation of response to food
0.64	GO:0045409	negative regulation of interleukin-6 biosynthetic process
0.64	GO:0060124	positive regulation of growth hormone secretion
0.63	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep
0.63	GO:0032691	negative regulation of interleukin-1 beta production
0.63	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
0.62	GO:0046697	decidualization
0.62	GO:0051461	positive regulation of corticotropin secretion

0.87	GO:0016608	growth hormone-releasing hormone activity
0.62	GO:0030296	protein tyrosine kinase activator activity
0.56	GO:0031768	ghrelin receptor binding

0.66	GO:0005576	extracellular region
0.57	GO:0030424	axon
0.53	GO:0098794	postsynapse
0.39	GO:0005737	cytoplasm
0.36	GO:0031983	vesicle lumen
0.35	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|Q9BEH0|IL1RA_CANLF
Interleukin-1 receptor antagonist protein
Search

IL1RN

0.81	Interleukin 1 receptor antagonist

0.79	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.73	GO:0006955	immune response
0.67	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.65	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.62	GO:0030073	insulin secretion
0.62	GO:0051384	response to glucocorticoid
0.53	GO:0031649	heat generation
0.50	GO:0019221	cytokine-mediated signaling pathway
0.48	GO:0006629	lipid metabolic process

0.86	GO:0005149	interleukin-1 receptor binding
0.80	GO:0005125	cytokine activity
0.68	GO:0045352	interleukin-1 Type I receptor antagonist activity
0.68	GO:0045353	interleukin-1 Type II receptor antagonist activity
0.34	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.73	GO:0005615	extracellular space
0.53	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.34	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane

sp|Q9BGL8|PE2R1_CANLF
Prostaglandin E2 receptor EP1 subtype
Search

PTGER1

0.97	Prostaglandin E receptor 1

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0032496	response to lipopolysaccharide
0.48	GO:0071798	response to prostaglandin D
0.47	GO:0071379	cellular response to prostaglandin stimulus
0.47	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.46	GO:0032355	response to estradiol
0.44	GO:0008284	positive regulation of cell proliferation
0.44	GO:0043066	negative regulation of apoptotic process
0.42	GO:0010628	positive regulation of gene expression
0.34	GO:0007567	parturition

0.85	GO:0004955	prostaglandin receptor activity
0.53	GO:0004960	thromboxane receptor activity

0.41	GO:0005886	plasma membrane
0.40	GO:0005576	extracellular region
0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9GJU1|DRD2_CANLF
D(2) dopamine receptor
Search

DRD2

0.95	Dopamine receptor 2 protein transcript variant 1

0.86	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway
0.64	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.63	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway
0.63	GO:0048148	behavioral response to cocaine
0.62	GO:0014059	regulation of dopamine secretion
0.62	GO:0048149	behavioral response to ethanol
0.62	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.61	GO:1900166	regulation of glial cell-derived neurotrophic factor secretion
0.61	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.61	GO:0035815	positive regulation of renal sodium excretion

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.63	GO:0035240	dopamine binding
0.52	GO:0042802	identical protein binding
0.49	GO:0004935	adrenergic receptor activity
0.41	GO:0035255	ionotropic glutamate receptor binding
0.38	GO:0046982	protein heterodimerization activity
0.35	GO:0015459	potassium channel regulator activity

0.66	GO:0005887	integral component of plasma membrane
0.57	GO:0060170	ciliary membrane
0.56	GO:0097730	non-motile cilium
0.55	GO:0097458	neuron part
0.50	GO:0099501	exocytic vesicle membrane
0.46	GO:0044456	synapse part
0.40	GO:0016328	lateral plasma membrane
0.40	GO:0036126	sperm flagellum
0.40	GO:0001669	acrosomal vesicle
0.40	GO:0032279	asymmetric synapse

sp|Q9GK08|MSX2_CANLF
Homeobox protein MSX-2
Search

MSX2

0.94	Muscle segment homeobox 3

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.51	GO:0051253	negative regulation of RNA metabolic process
0.51	GO:0010558	negative regulation of macromolecule biosynthetic process
0.51	GO:0031327	negative regulation of cellular biosynthetic process
0.50	GO:2001055	positive regulation of mesenchymal cell apoptotic process
0.50	GO:0090427	activation of meiosis
0.50	GO:0035880	embryonic nail plate morphogenesis
0.50	GO:0060364	frontal suture morphogenesis

0.62	GO:0043565	sequence-specific DNA binding
0.46	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0044212	transcription regulatory region DNA binding
0.44	GO:0003712	transcription cofactor activity
0.43	GO:0003690	double-stranded DNA binding
0.43	GO:0008134	transcription factor binding
0.35	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0002039	p53 binding
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.59	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.33	GO:0005667	transcription factor complex

sp|Q9GKK4|GALK1_CANLF
Galactokinase
Search

GALK1

0.51	Epididymis secretory protein Li 19

0.76	GO:0006012	galactose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.61	GO:0061622	glycolytic process through glucose-1-phosphate
0.56	GO:0019402	galactitol metabolic process
0.53	GO:0019320	hexose catabolic process
0.34	GO:0051260	protein homooligomerization

0.81	GO:0004335	galactokinase activity
0.75	GO:0005534	galactose binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81	EC:2.7.1.6	GO:0004335
0.81	KEGG:R01092	GO:0004335

sp|Q9GKK5|TBG1_CANLF
Tubulin gamma-1 chain
Search

TUBG1

0.70	Tubulin gamma chain

0.84	GO:0031122	cytoplasmic microtubule organization
0.81	GO:0007020	microtubule nucleation
0.47	GO:0000212	meiotic spindle organization
0.35	GO:0007346	regulation of mitotic cell cycle
0.35	GO:1903047	mitotic cell cycle process
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0010564	regulation of cell cycle process
0.35	GO:0044839	cell cycle G2/M phase transition
0.34	GO:0051783	regulation of nuclear division

0.68	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042802	identical protein binding
0.35	GO:0005200	structural constituent of cytoskeleton

0.84	GO:0000930	gamma-tubulin complex
0.73	GO:0005874	microtubule
0.54	GO:0000242	pericentriolar material
0.51	GO:0005819	spindle
0.47	GO:0055037	recycling endosome
0.46	GO:0036064	ciliary basal body
0.46	GO:0097730	non-motile cilium
0.46	GO:0005814	centriole
0.45	GO:0045177	apical part of cell
0.45	GO:0031252	cell leading edge

tr|Q9GKP2|Q9GKP2_CANLF
Costimulatory molecule B7 receptor CD152
Search

CTLA4

0.97	Soluble form of cytotoxic T-lymphocyte antigen 4

0.74	GO:0006955	immune response
0.69	GO:0045590	negative regulation of regulatory T cell differentiation
0.67	GO:0030889	negative regulation of B cell proliferation
0.65	GO:0050853	B cell receptor signaling pathway
0.60	GO:0043065	positive regulation of apoptotic process
0.51	GO:0006974	cellular response to DNA damage stimulus
0.43	GO:0042130	negative regulation of T cell proliferation
0.40	GO:0050777	negative regulation of immune response
0.36	GO:0031295	T cell costimulation

0.37	GO:0005515	protein binding
0.36	GO:0004872	receptor activity

0.64	GO:0045334	clathrin-coated endocytic vesicle
0.62	GO:0009897	external side of plasma membrane
0.62	GO:0098636	protein complex involved in cell adhesion
0.60	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0005794	Golgi apparatus
0.54	GO:0005887	integral component of plasma membrane

tr|Q9GKP3|Q9GKP3_CANLF
Costimulatory molecule B7 receptor CD28
Search

CD28

0.96	T-cell-specific surface glycoprotein CD28

0.73	GO:0006955	immune response
0.67	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.64	GO:0042102	positive regulation of T cell proliferation
0.64	GO:0045840	positive regulation of mitotic nuclear division
0.62	GO:0032753	positive regulation of interleukin-4 production
0.61	GO:0045066	regulatory T cell differentiation
0.61	GO:0032733	positive regulation of interleukin-10 production
0.60	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.60	GO:0002863	positive regulation of inflammatory response to antigenic stimulus
0.60	GO:0045060	negative thymic T cell selection

0.58	GO:0005070	SH3/SH2 adaptor activity
0.57	GO:0002020	protease binding
0.54	GO:0019901	protein kinase binding
0.38	GO:0015026	coreceptor activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0042802	identical protein binding
0.34	GO:0046983	protein dimerization activity

0.58	GO:0001772	immunological synapse
0.56	GO:0009897	external side of plasma membrane
0.56	GO:0098636	protein complex involved in cell adhesion
0.40	GO:0044214	spanning component of plasma membrane
0.35	GO:0045121	membrane raft
0.34	GO:0005829	cytosol

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|Q9GKQ8|DSG1_CANLF
Desmoglein-1
Search

DSG1

0.82	Desmosomal glycoprotein 1

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0030216	keratinocyte differentiation
0.56	GO:0001942	hair follicle development
0.55	GO:0030509	BMP signaling pathway
0.49	GO:0050821	protein stabilization
0.38	GO:0003165	Purkinje myocyte development
0.38	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.37	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.37	GO:0002934	desmosome organization
0.37	GO:0086091	regulation of heart rate by cardiac conduction

0.70	GO:0005509	calcium ion binding
0.53	GO:0045295	gamma-catenin binding
0.36	GO:0050839	cell adhesion molecule binding
0.32	GO:0015643	toxic substance binding

0.58	GO:0005911	cell-cell junction
0.55	GO:0005886	plasma membrane
0.54	GO:0070161	anchoring junction
0.47	GO:0098562	cytoplasmic side of membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0031012	extracellular matrix
0.34	GO:0005829	cytosol
0.34	GO:0045177	apical part of cell
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0101003	ficolin-1-rich granule membrane

sp|Q9GL21|UACA_CANLF
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Search

UACA

0.97	Uveal autoantigen with coiled-coil domains and ankyrin repeats

0.84	GO:1901222	regulation of NIK/NF-kappaB signaling
0.80	GO:0097190	apoptotic signaling pathway
0.40	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.39	GO:0036473	cell death in response to oxidative stress
0.39	GO:0050728	negative regulation of inflammatory response
0.39	GO:0042307	positive regulation of protein import into nucleus
0.39	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.38	GO:0009411	response to UV
0.36	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0035556	intracellular signal transduction

0.35

GO:0005515

protein binding

0.49	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005856	cytoskeleton
0.36	GO:0012505	endomembrane system
0.35	GO:0031967	organelle envelope
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9GL23|APAF_CANLF
Apoptotic protease-activating factor 1 (Fragment)
Search

0.55	Apoptotic protease-activating factor 1 (Fragment)

0.75	GO:0097190	apoptotic signaling pathway
0.74	GO:0042981	regulation of apoptotic process
0.63	GO:1903624	regulation of DNA catabolic process
0.60	GO:0051402	neuron apoptotic process
0.60	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.59	GO:0001843	neural tube closure
0.57	GO:0030900	forebrain development
0.56	GO:0043068	positive regulation of programmed cell death
0.56	GO:0034976	response to endoplasmic reticulum stress
0.54	GO:0009967	positive regulation of signal transduction

0.74	GO:0043531	ADP binding
0.63	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.53	GO:0042802	identical protein binding
0.50	GO:0005524	ATP binding
0.50	GO:0008233	peptidase activity
0.39	GO:0031072	heat shock protein binding

0.83	GO:0043293	apoptosome
0.46	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.37	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen

0.50

EC:3.4

GO:0008233

sp|Q9GL24|CATL1_CANLF
Cathepsin L1
Search

0.71	Cathepsin V

0.61	GO:0006508	proteolysis
0.49	GO:0010839	negative regulation of keratinocyte proliferation
0.49	GO:0046697	decidualization
0.49	GO:0031069	hair follicle morphogenesis
0.48	GO:2000249	regulation of actin cytoskeleton reorganization
0.47	GO:0044257	cellular protein catabolic process
0.45	GO:0097067	cellular response to thyroid hormone stimulus
0.44	GO:0030574	collagen catabolic process
0.43	GO:0051604	protein maturation
0.43	GO:0002250	adaptive immune response

0.72	GO:0008234	cysteine-type peptidase activity
0.50	GO:0042393	histone binding
0.47	GO:0097655	serpin family protein binding
0.45	GO:0004175	endopeptidase activity
0.45	GO:0001968	fibronectin binding
0.44	GO:0043394	proteoglycan binding
0.44	GO:0004180	carboxypeptidase activity
0.43	GO:0005518	collagen binding
0.41	GO:0030984	kininogen binding
0.38	GO:0042277	peptide binding

0.55	GO:0005764	lysosome
0.51	GO:0005615	extracellular space
0.44	GO:0031410	cytoplasmic vesicle
0.44	GO:0005730	nucleolus
0.40	GO:0043204	perikaryon
0.39	GO:0005902	microvillus
0.39	GO:0009897	external side of plasma membrane
0.39	GO:0045177	apical part of cell
0.38	GO:0043005	neuron projection
0.37	GO:0012505	endomembrane system

0.72

EC:3.4

GO:0008234

sp|Q9GL25|ESPB1_CANLF
Epididymal sperm-binding protein 1
Search

ELSPBP1

0.97	Epididymal sperm-binding protein 1

0.68	GO:0048240	sperm capacitation
0.64	GO:0030574	collagen catabolic process
0.61	GO:0050900	leukocyte migration
0.61	GO:0001503	ossification
0.51	GO:0006508	proteolysis
0.50	GO:0007338	single fertilization
0.48	GO:0050729	positive regulation of inflammatory response
0.47	GO:0006954	inflammatory response
0.47	GO:0042060	wound healing
0.46	GO:0051919	positive regulation of fibrinolysis

0.64	GO:0008201	heparin binding
0.54	GO:0004222	metalloendopeptidase activity
0.50	GO:0008270	zinc ion binding
0.43	GO:0004252	serine-type endopeptidase activity
0.42	GO:0005509	calcium ion binding
0.38	GO:0005178	integrin binding

0.59	GO:0009986	cell surface
0.59	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.54

EC:3.4.24

GO:0004222

sp|Q9GL27|BRAC_CANLF
Brachyury protein
Search

0.96	T-box transcription factor Brachyury

0.62	GO:0014028	notochord formation
0.61	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.60	GO:0036342	post-anal tail morphogenesis
0.59	GO:0007341	penetration of zona pellucida
0.59	GO:0007509	mesoderm migration involved in gastrulation
0.59	GO:0001839	neural plate morphogenesis
0.59	GO:0001756	somitogenesis
0.59	GO:0061371	determination of heart left/right asymmetry
0.58	GO:0023019	signal transduction involved in regulation of gene expression
0.58	GO:0003007	heart morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0001158	enhancer sequence-specific DNA binding
0.58	GO:0001102	RNA polymerase II activating transcription factor binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.36	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.51	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9GLD3|TFR1_CANLF
Transferrin receptor protein 1
Search

TFRC

0.93	Transferrin receptor

0.85	GO:0033572	transferrin transport
0.73	GO:0006879	cellular iron ion homeostasis
0.69	GO:0006898	receptor-mediated endocytosis
0.59	GO:0045830	positive regulation of isotype switching
0.59	GO:0030890	positive regulation of B cell proliferation
0.58	GO:0042102	positive regulation of T cell proliferation
0.57	GO:0097286	iron ion import
0.57	GO:0046852	positive regulation of bone remodeling
0.56	GO:0045124	regulation of bone resorption
0.56	GO:0030316	osteoclast differentiation

0.85	GO:0033570	transferrin transmembrane transporter activity
0.85	GO:0004998	transferrin receptor activity
0.51	GO:0003725	double-stranded RNA binding
0.51	GO:0042803	protein homodimerization activity
0.35	GO:0104005	hijacked molecular function
0.35	GO:0030544	Hsp70 protein binding
0.34	GO:0051087	chaperone binding

0.57	GO:1990712	HFE-transferrin receptor complex
0.55	GO:0055037	recycling endosome
0.54	GO:0016323	basolateral plasma membrane
0.54	GO:0009897	external side of plasma membrane
0.54	GO:0005905	clathrin-coated pit
0.53	GO:0070062	extracellular exosome
0.53	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005769	early endosome
0.52	GO:0010008	endosome membrane
0.47	GO:0005887	integral component of plasma membrane

sp|Q9GLF6|OREX_CANLF
Orexin
Search

HCRT

0.92	Hypocretin neuropeptide precursor

0.84	GO:0007631	feeding behavior
0.80	GO:0007218	neuropeptide signaling pathway
0.60	GO:0042746	circadian sleep/wake cycle, wakefulness
0.56	GO:0030431	sleep
0.55	GO:0033555	multicellular organismal response to stress
0.51	GO:0042594	response to starvation
0.35	GO:0035556	intracellular signal transduction

0.50	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0005783	endoplasmic reticulum
0.30	GO:0030054	cell junction
0.30	GO:0045202	synapse
0.30	GO:0031982	vesicle

sp|Q9GLJ9|SCAMP_CANLF
Putative protein SCAMPER
Search

SCAMPER

0.97

SCAMPER

0.85	GO:0033017	sarcoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9GLK0|TGM1_CANLF
Protein-glutamine gamma-glutamyltransferase K
Search

TGM1

0.97	Glutamine gamma-glutamyltransferase K

0.84	GO:0018149	peptide cross-linking
0.61	GO:0010838	positive regulation of keratinocyte proliferation
0.58	GO:0030216	keratinocyte differentiation
0.55	GO:0045787	positive regulation of cell cycle
0.37	GO:0009887	animal organ morphogenesis
0.36	GO:0043163	cell envelope organization
0.35	GO:0012501	programmed cell death
0.34	GO:0051262	protein tetramerization
0.34	GO:0072378	blood coagulation, fibrin clot formation
0.33	GO:0098869	cellular oxidant detoxification

0.84	GO:0003810	protein-glutamine gamma-glutamyltransferase activity
0.36	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.33	GO:0004096	catalase activity
0.32	GO:0020037	heme binding
0.32	GO:0003677	DNA binding

0.38	GO:0005913	cell-cell adherens junction
0.37	GO:0070062	extracellular exosome
0.36	GO:0001533	cornified envelope
0.35	GO:0005737	cytoplasm
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.3.2.13

GO:0003810

sp|Q9GLW0|PRGR_CANLF
Progesterone receptor
Search

PGR

0.96	Progesterone receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0038001	paracrine signaling
0.57	GO:0030728	ovulation
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0002070	epithelial cell maturation
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048286	lung alveolus development

0.79	GO:0003707	steroid hormone receptor activity
0.72	GO:0005496	steroid binding
0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.59	GO:0003700	DNA binding transcription factor activity
0.56	GO:0051117	ATPase binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0042802	identical protein binding
0.49	GO:0003690	double-stranded DNA binding
0.38	GO:0005102	receptor binding

0.61	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.36	GO:0043204	perikaryon
0.36	GO:0043197	dendritic spine
0.36	GO:0043679	axon terminus
0.36	GO:0030424	axon
0.35	GO:0031968	organelle outer membrane
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0012505	endomembrane system
0.34	GO:0043235	receptor complex

sp|Q9GMY1|QKI_CANLF
Protein quaking
Search

QKI

0.96	Quaking homolog, KH domain RNA binding

0.46	GO:0061158	3'-UTR-mediated mRNA destabilization
0.45	GO:0030154	cell differentiation
0.45	GO:0042759	long-chain fatty acid biosynthetic process
0.45	GO:0007275	multicellular organism development
0.44	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.43	GO:0007283	spermatogenesis
0.43	GO:0061061	muscle structure development
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.42	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.46	GO:0017124	SH3 domain binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

sp|Q9GMY6|PEPA_CANLF
Pepsin A
Search

0.91	Pepsinogen III

0.61	GO:0006508	proteolysis
0.49	GO:0007586	digestion
0.48	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.45	GO:0051604	protein maturation
0.43	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.40	GO:0042803	protein homodimerization activity

0.43	GO:0005576	extracellular region
0.42	GO:0005768	endosome
0.37	GO:0044433	cytoplasmic vesicle part
0.36	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9GMZ1|UCP1_CANLF
Mitochondrial brown fat uncoupling protein 1
Search

UCP1

0.93	Mitochondrial brown fat uncoupling protein 1

0.77	GO:0006839	mitochondrial transport
0.62	GO:1990845	adaptive thermogenesis
0.56	GO:0070542	response to fatty acid
0.55	GO:1903426	regulation of reactive oxygen species biosynthetic process
0.54	GO:0009628	response to abiotic stimulus
0.53	GO:0002021	response to dietary excess
0.53	GO:0071229	cellular response to acid chemical
0.53	GO:0050873	brown fat cell differentiation
0.52	GO:0000302	response to reactive oxygen species
0.52	GO:0032870	cellular response to hormone stimulus

0.64	GO:0017077	oxidative phosphorylation uncoupler activity
0.57	GO:0036041	long-chain fatty acid binding
0.48	GO:1901612	cardiolipin binding
0.41	GO:0032555	purine ribonucleotide binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0031966	mitochondrial membrane
0.47	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9MYU8|E41L5_CANLF
Band 4.1-like protein 5
Search

EPB41L5

0.94	Erythrocyte membrane protein band 4.1 like 5

0.57	GO:0006931	substrate-dependent cell migration, cell attachment to substrate
0.56	GO:0048319	axial mesoderm morphogenesis
0.56	GO:0007509	mesoderm migration involved in gastrulation
0.56	GO:0048617	embryonic foregut morphogenesis
0.56	GO:0001839	neural plate morphogenesis
0.56	GO:0032525	somite rostral/caudal axis specification
0.55	GO:0003383	apical constriction
0.55	GO:0031032	actomyosin structure organization
0.55	GO:0070986	left/right axis specification
0.55	GO:0051894	positive regulation of focal adhesion assembly

0.69	GO:0008092	cytoskeletal protein binding
0.50	GO:0019904	protein domain specific binding
0.45	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003735	structural constituent of ribosome

0.79	GO:0005912	adherens junction
0.68	GO:0005856	cytoskeleton
0.53	GO:0032587	ruffle membrane
0.52	GO:0030055	cell-substrate junction
0.47	GO:0005829	cytosol
0.45	GO:0005923	bicellular tight junction
0.44	GO:0005634	nucleus
0.39	GO:0043234	protein complex
0.33	GO:0005840	ribosome

sp|Q9MYV1|CALCA_CANLF
Calcitonin gene-related peptide 1
Search

0.96	Calcitonin receptor-stimulating peptide 1

0.76	GO:0010469	regulation of receptor activity
0.43	GO:0055074	calcium ion homeostasis
0.40	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure
0.40	GO:0007190	activation of adenylate cyclase activity
0.39	GO:0045776	negative regulation of blood pressure
0.39	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.39	GO:0097755	positive regulation of blood vessel diameter
0.39	GO:0072503	cellular divalent inorganic cation homeostasis
0.39	GO:1990408	calcitonin gene-related peptide receptor signaling pathway
0.38	GO:0045779	negative regulation of bone resorption

0.79	GO:0005179	hormone activity
0.39	GO:0031716	calcitonin receptor binding
0.36	GO:0032403	protein complex binding
0.35	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.38	GO:0043195	terminal bouton
0.37	GO:0043025	neuronal cell body
0.33	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9MYV3|VEGFA_CANLF
Vascular endothelial growth factor A
Search

VEGFA

0.93	Vascular endothelial growth factor A

0.75	GO:0010469	regulation of receptor activity
0.56	GO:1903570	regulation of protein kinase D signaling
0.56	GO:0050927	positive regulation of positive chemotaxis
0.55	GO:0001938	positive regulation of endothelial cell proliferation
0.55	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
0.55	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.55	GO:0038091	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
0.54	GO:0045766	positive regulation of angiogenesis
0.54	GO:0090037	positive regulation of protein kinase C signaling
0.54	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway

0.78	GO:0008083	growth factor activity
0.77	GO:0008201	heparin binding
0.58	GO:0043183	vascular endothelial growth factor receptor 1 binding
0.57	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.53	GO:0001968	fibronectin binding
0.53	GO:0005161	platelet-derived growth factor receptor binding
0.53	GO:0042056	chemoattractant activity
0.50	GO:0005125	cytokine activity
0.40	GO:0038191	neuropilin binding
0.39	GO:0050840	extracellular matrix binding

0.50	GO:0030141	secretory granule
0.48	GO:0009986	cell surface
0.48	GO:0005615	extracellular space
0.36	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0044420	extracellular matrix component
0.34	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9MYY9|KCNJ2_CANLF
Inward rectifier potassium channel 2
Search

KCNJ2

0.86	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.62	GO:0014861	regulation of skeletal muscle contraction via regulation of action potential
0.62	GO:0090076	relaxation of skeletal muscle
0.61	GO:0098655	cation transmembrane transport
0.61	GO:0055119	relaxation of cardiac muscle
0.60	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.59	GO:0086002	cardiac muscle cell action potential involved in contraction
0.59	GO:0086091	regulation of heart rate by cardiac conduction
0.58	GO:0051289	protein homotetramerization

0.84	GO:0005242	inward rectifier potassium channel activity
0.60	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
0.57	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.51	GO:0042802	identical protein binding

0.53	GO:0008076	voltage-gated potassium channel complex
0.39	GO:0005790	smooth endoplasmic reticulum
0.39	GO:0030315	T-tubule
0.39	GO:0014704	intercalated disc
0.39	GO:0043197	dendritic spine
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0043025	neuronal cell body
0.37	GO:0005794	Golgi apparatus

sp|Q9MZF4|DUOX1_CANLF
Dual oxidase 1
Search

DUOX1

0.95	Dual oxidase 1

0.85	GO:0050665	hydrogen peroxide biosynthetic process
0.70	GO:0006979	response to oxidative stress
0.68	GO:0098869	cellular oxidant detoxification
0.61	GO:0051591	response to cAMP
0.57	GO:0019221	cytokine-mediated signaling pathway
0.55	GO:0042335	cuticle development
0.54	GO:0042403	thyroid hormone metabolic process
0.52	GO:0048855	adenohypophysis morphogenesis
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0030878	thyroid gland development

0.85	GO:0016174	NAD(P)H oxidase activity
0.71	GO:0004601	peroxidase activity
0.69	GO:0005509	calcium ion binding
0.62	GO:0020037	heme binding
0.36	GO:0050661	NADP binding
0.34	GO:0005515	protein binding

0.42	GO:0016324	apical plasma membrane
0.36	GO:0030054	cell junction
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.85	EC:1.6.3.1	GO:0016174
0.71	KEGG:R03532	GO:0004601

sp|Q9MZI6|GNRHR_CANLF
Gonadotropin-releasing hormone receptor
Search

GNRHR

0.87	Pituitary gonadotropin releasing hormone receptor

0.78	GO:0097211	cellular response to gonadotropin-releasing hormone
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0021764	amygdala development
0.36	GO:0060996	dendritic spine development
0.36	GO:0021766	hippocampus development
0.36	GO:0007612	learning
0.36	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.36	GO:0007626	locomotory behavior
0.36	GO:0007623	circadian rhythm
0.35	GO:0008285	negative regulation of cell proliferation

0.83	GO:0016500	protein-hormone receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.45	GO:0042277	peptide binding
0.38	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.36	GO:0001653	peptide receptor activity
0.34	GO:0005515	protein binding

0.42	GO:0005887	integral component of plasma membrane
0.32	GO:0005737	cytoplasm

sp|Q9MZT1|CLCN1_CANLF
Chloride channel protein 1
Search

CLCN1

0.51	Chloride voltage-gated channel 1

0.77	GO:1902476	chloride transmembrane transport
0.63	GO:0098870	action potential propagation
0.60	GO:0019226	transmission of nerve impulse
0.58	GO:0006936	muscle contraction
0.43	GO:0060689	cell differentiation involved in salivary gland development
0.41	GO:0060041	retina development in camera-type eye
0.40	GO:0034765	regulation of ion transmembrane transport

0.78	GO:0005247	voltage-gated chloride channel activity
0.54	GO:0042803	protein homodimerization activity

0.59	GO:0042383	sarcolemma
0.50	GO:0005887	integral component of plasma membrane
0.41	GO:0034707	chloride channel complex
0.37	GO:0030054	cell junction
0.32	GO:0005622	intracellular

sp|Q9MZV7|CASP1_CANLF
Caspase-1
Search

0.87	Caspase 4, apoptosis-related cysteine peptidase

0.69	GO:0042981	regulation of apoptotic process
0.61	GO:0006508	proteolysis
0.57	GO:0012501	programmed cell death
0.55	GO:0050727	regulation of inflammatory response
0.53	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.51	GO:0050718	positive regulation of interleukin-1 beta secretion
0.49	GO:0071310	cellular response to organic substance
0.49	GO:0071260	cellular response to mechanical stimulus
0.47	GO:0010243	response to organonitrogen compound
0.47	GO:0034976	response to endoplasmic reticulum stress

0.75	GO:0004197	cysteine-type endopeptidase activity
0.53	GO:0050700	CARD domain binding
0.44	GO:0019900	kinase binding
0.43	GO:0042802	identical protein binding
0.36	GO:0097110	scaffold protein binding
0.35	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.34	GO:0002020	protease binding

0.62	GO:0061702	inflammasome complex
0.48	GO:0097179	protease inhibitor complex
0.44	GO:0005783	endoplasmic reticulum
0.41	GO:0005739	mitochondrion
0.40	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.35	GO:0043005	neuron projection
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.34	GO:0043025	neuronal cell body

0.75

EC:3.4.22

GO:0004197

sp|Q9MZY0|CP2E1_CANLF
Cytochrome P450 2E1
Search

CYP2E1

0.86	Cytochrome P450 family 2 subfamily e polypeptide 1

0.56	GO:0019373	epoxygenase P450 pathway
0.54	GO:0016098	monoterpenoid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0008202	steroid metabolic process
0.41	GO:0017144	drug metabolic process
0.39	GO:0010193	response to ozone
0.38	GO:0045471	response to ethanol
0.38	GO:0006805	xenobiotic metabolic process
0.38	GO:0043651	linoleic acid metabolic process
0.38	GO:0006641	triglyceride metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0019899	enzyme binding
0.39	GO:0019825	oxygen binding
0.34	GO:0010181	FMN binding

0.47	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.36	GO:0044431	Golgi apparatus part
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:1.14

GO:0016705

sp|Q9N0W9|IL13_CANLF
Interleukin-13
Search

IL13

0.97	Interleukin 13 (Predicted)

0.74	GO:0006955	immune response
0.69	GO:1903660	negative regulation of complement-dependent cytotoxicity
0.65	GO:2000352	negative regulation of endothelial cell apoptotic process
0.64	GO:0043306	positive regulation of mast cell degranulation
0.63	GO:0043032	positive regulation of macrophage activation
0.62	GO:0002639	positive regulation of immunoglobulin production
0.58	GO:0006954	inflammatory response
0.57	GO:0071345	cellular response to cytokine stimulus
0.49	GO:0010469	regulation of receptor activity
0.42	GO:0032643	regulation of connective tissue growth factor production

0.79	GO:0005126	cytokine receptor binding
0.51	GO:0005125	cytokine activity
0.35	GO:0016887	ATPase activity
0.34	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.59	GO:0009897	external side of plasma membrane
0.41	GO:0005737	cytoplasm
0.38	GO:0030870	Mre11 complex
0.30	GO:0016021	integral component of membrane

0.35

EC:3.6.1.3

GO:0016887

sp|Q9N0Y2|MX2_CANLF
Interferon-induced GTP-binding protein Mx2
Search

MX2

0.95	Myxovirus resistance protein 2

0.43	GO:0035455	response to interferon-alpha
0.42	GO:0051607	defense response to virus
0.42	GO:0046822	regulation of nucleocytoplasmic transport
0.40	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.40	GO:0051726	regulation of cell cycle
0.39	GO:0000266	mitochondrial fission
0.38	GO:0045087	innate immune response
0.37	GO:0061025	membrane fusion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008017	microtubule binding

0.41	GO:0005643	nuclear pore
0.36	GO:0031966	mitochondrial membrane

sp|Q9N0Y3|MX1_CANLF
Interferon-induced GTP-binding protein Mx1
Search

MX1

0.82	Myxovirus resistance protein 1

0.41	GO:0035455	response to interferon-alpha
0.41	GO:0051607	defense response to virus
0.40	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.40	GO:0046822	regulation of nucleocytoplasmic transport
0.39	GO:0000266	mitochondrial fission
0.38	GO:0045087	innate immune response
0.38	GO:0051726	regulation of cell cycle
0.37	GO:0061025	membrane fusion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008017	microtubule binding

0.39	GO:0005643	nuclear pore
0.36	GO:0031966	mitochondrial membrane

sp|Q9N1R2|EAA4_CANLF
Excitatory amino acid transporter 4
Search

SLC1A6

0.45	Amino acid transporter

0.56	GO:0089711	L-glutamate transmembrane transport
0.50	GO:0042391	regulation of membrane potential
0.49	GO:0089718	amino acid import across plasma membrane
0.49	GO:1903802	L-glutamate(1-) import across plasma membrane
0.49	GO:0001504	neurotransmitter uptake
0.47	GO:0089712	L-aspartate transmembrane transport
0.47	GO:0070779	D-aspartate import
0.47	GO:0009449	gamma-aminobutyric acid biosynthetic process
0.46	GO:0031223	auditory behavior
0.45	GO:0021545	cranial nerve development

0.72	GO:0015293	symporter activity
0.56	GO:0005313	L-glutamate transmembrane transporter activity
0.46	GO:0016595	glutamate binding
0.44	GO:0015081	sodium ion transmembrane transporter activity
0.41	GO:0022853	active ion transmembrane transporter activity
0.36	GO:0015183	L-aspartate transmembrane transporter activity
0.35	GO:0046872	metal ion binding

0.51	GO:0045111	intermediate filament cytoskeleton
0.47	GO:0005794	Golgi apparatus
0.43	GO:0043025	neuronal cell body
0.42	GO:0043005	neuron projection
0.42	GO:0009986	cell surface
0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0098794	postsynapse
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0019866	organelle inner membrane

sp|Q9N1T2|RPGR_CANLF
X-linked retinitis pigmentosa GTPase regulator
Search

RPGR

0.92	X-linked retinitis pigmentosa GTPase regulator

0.80	GO:0060271	cilium assembly
0.77	GO:0042073	intraciliary transport
0.73	GO:0007601	visual perception
0.61	GO:0065009	regulation of molecular function
0.60	GO:0042462	eye photoreceptor cell development
0.60	GO:0060042	retina morphogenesis in camera-type eye
0.59	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.56	GO:0003407	neural retina development
0.53	GO:0050896	response to stimulus
0.51	GO:0048646	anatomical structure formation involved in morphogenesis

0.69	GO:0005085	guanyl-nucleotide exchange factor activity
0.46	GO:0003723	RNA binding

0.78	GO:0036126	sperm flagellum
0.76	GO:0036064	ciliary basal body
0.73	GO:0005813	centrosome
0.67	GO:0005794	Golgi apparatus
0.63	GO:0001750	photoreceptor outer segment
0.46	GO:0032391	photoreceptor connecting cilium

tr|Q9N280|Q9N280_CANLF
Amino acid transporter
Search

SLC1A3

0.45	Amino acid transporter

0.59	GO:0140016	D-aspartate import across plasma membrane
0.59	GO:0140009	L-aspartate import across plasma membrane
0.59	GO:0009449	gamma-aminobutyric acid biosynthetic process
0.58	GO:0098712	L-glutamate import across plasma membrane
0.57	GO:0031223	auditory behavior
0.56	GO:0021545	cranial nerve development
0.55	GO:0050885	neuromuscular process controlling balance
0.55	GO:0050806	positive regulation of synaptic transmission
0.53	GO:0007605	sensory perception of sound
0.52	GO:0048667	cell morphogenesis involved in neuron differentiation

0.72	GO:0015293	symporter activity
0.58	GO:0016595	glutamate binding
0.55	GO:0005313	L-glutamate transmembrane transporter activity
0.50	GO:0015081	sodium ion transmembrane transporter activity
0.48	GO:0022853	active ion transmembrane transporter activity
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.53	GO:0043025	neuronal cell body
0.51	GO:0043005	neuron projection
0.51	GO:0009986	cell surface
0.47	GO:0005887	integral component of plasma membrane
0.35	GO:0016323	basolateral plasma membrane
0.34	GO:0098794	postsynapse
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0045111	intermediate filament cytoskeleton
0.33	GO:0005794	Golgi apparatus
0.33	GO:0019866	organelle inner membrane

sp|Q9N281|COHA1_CANLF
Collagen alpha-1(XVII) chain
Search

COL17A1

0.96	Collagen type XVII alpha 1 chain

0.61	GO:0031581	hemidesmosome assembly
0.40	GO:0048925	lateral line system development
0.38	GO:0008544	epidermis development
0.36	GO:0007160	cell-matrix adhesion
0.35	GO:0050776	regulation of immune response

0.35

GO:0005515

protein binding

0.63	GO:0005581	collagen trimer
0.62	GO:0030056	hemidesmosome
0.42	GO:0005604	basement membrane
0.37	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0005911	cell-cell junction
0.35	GO:0005887	integral component of plasma membrane

sp|Q9N2G9|LALBA_CANLF
Alpha-lactalbumin
Search

LALBA

0.91	Alpha-lactalbumin protein variant D

0.86	GO:0005989	lactose biosynthetic process
0.45	GO:0042742	defense response to bacterium
0.44	GO:1903496	response to 11-deoxycorticosterone
0.44	GO:1903494	response to dehydroepiandrosterone
0.42	GO:0032570	response to progesterone
0.42	GO:0016998	cell wall macromolecule catabolic process
0.42	GO:0032355	response to estradiol
0.34	GO:0006915	apoptotic process
0.34	GO:0007267	cell-cell signaling
0.33	GO:0019835	cytolysis

0.86	GO:0004461	lactose synthase activity
0.68	GO:0005509	calcium ion binding
0.49	GO:0003796	lysozyme activity
0.34	GO:0005515	protein binding

0.45	GO:0005576	extracellular region
0.35	GO:0005796	Golgi lumen
0.34	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.4.1.22

GO:0004461

sp|Q9N2I9|UCP3_CANLF
Mitochondrial uncoupling protein 3
Search

UCP3

0.86	Mitochondrial uncoupling protein A

0.77	GO:0006839	mitochondrial transport
0.53	GO:0001666	response to hypoxia
0.53	GO:1990845	adaptive thermogenesis
0.52	GO:0051881	regulation of mitochondrial membrane potential
0.50	GO:0000303	response to superoxide
0.50	GO:0009409	response to cold
0.47	GO:0015992	proton transport
0.46	GO:0006631	fatty acid metabolic process
0.43	GO:0032868	response to insulin
0.42	GO:0007568	aging

0.62	GO:0017077	oxidative phosphorylation uncoupler activity
0.34	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.61	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9N2J1|UCP2_CANLF
Mitochondrial uncoupling protein 2
Search

UCP2

0.91	Mitochondrial uncoupling protein B

0.76	GO:0006839	mitochondrial transport
0.55	GO:0051881	regulation of mitochondrial membrane potential
0.55	GO:0001666	response to hypoxia
0.51	GO:1990845	adaptive thermogenesis
0.48	GO:0009409	response to cold
0.44	GO:0000303	response to superoxide
0.43	GO:0015992	proton transport
0.42	GO:0032868	response to insulin
0.42	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.41	GO:0007568	aging

0.55	GO:0017077	oxidative phosphorylation uncoupler activity
0.34	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.61	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9N2J4|AQP1_CANLF
Aquaporin-1
Search

AQP1

0.89	Aquaporin FA-CHIP

0.59	GO:0085018	maintenance of symbiont-containing vacuole by host
0.57	GO:0003097	renal water transport
0.57	GO:0072230	metanephric proximal straight tubule development
0.57	GO:0072232	metanephric proximal convoluted tubule segment 2 development
0.57	GO:0072220	metanephric descending thin limb development
0.56	GO:0021670	lateral ventricle development
0.56	GO:0051458	corticotropin secretion
0.55	GO:0072239	metanephric glomerulus vasculature development
0.55	GO:0055085	transmembrane transport
0.55	GO:0044241	lipid digestion

0.69	GO:0015267	channel activity
0.56	GO:0005372	water transmembrane transporter activity
0.54	GO:0035379	carbon dioxide transmembrane transporter activity
0.53	GO:0046875	ephrin receptor binding
0.49	GO:0015079	potassium ion transmembrane transporter activity
0.48	GO:0030184	nitric oxide transmembrane transporter activity
0.47	GO:0015168	glycerol transmembrane transporter activity
0.47	GO:0008519	ammonium transmembrane transporter activity
0.39	GO:0042802	identical protein binding

0.55	GO:0020003	symbiont-containing vacuole
0.55	GO:0009925	basal plasma membrane
0.54	GO:0005903	brush border
0.52	GO:0016324	apical plasma membrane
0.52	GO:0005901	caveola
0.51	GO:0070062	extracellular exosome
0.50	GO:0030424	axon
0.44	GO:0042383	sarcolemma
0.44	GO:0031253	cell projection membrane
0.43	GO:0031965	nuclear membrane

tr|Q9TQX1|Q9TQX1_CANLF
B7-1 protein
Search

CD80

0.97	T-cell specific surface glycoprotein B7-1

0.86	GO:0031295	T cell costimulation
0.63	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.60	GO:0007165	signal transduction
0.48	GO:0046635	positive regulation of alpha-beta T cell activation
0.47	GO:0046640	regulation of alpha-beta T cell proliferation
0.46	GO:0042102	positive regulation of T cell proliferation
0.45	GO:0071222	cellular response to lipopolysaccharide
0.38	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
0.38	GO:0045625	regulation of T-helper 1 cell differentiation
0.38	GO:0045086	positive regulation of interleukin-2 biosynthetic process

0.85	GO:0015026	coreceptor activity
0.38	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0104005	hijacked molecular function
0.36	GO:0005515	protein binding

0.59	GO:0098636	protein complex involved in cell adhesion
0.45	GO:0009897	external side of plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.38	EC:2.7.1.153	GO:0046934
0.38	KEGG:R04545	GO:0046934

sp|Q9TQX6|ACBP_CANLF
Acyl-CoA-binding protein
Search

DBI

0.61	Benzodiazepine receptor ligand

0.46	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.35	GO:0021670	lateral ventricle development
0.35	GO:0006952	defense response
0.34	GO:0042596	fear response
0.34	GO:0018345	protein palmitoylation
0.34	GO:0032228	regulation of synaptic transmission, GABAergic
0.34	GO:0060291	long-term synaptic potentiation
0.34	GO:0030242	autophagy of peroxisome
0.34	GO:0001942	hair follicle development
0.34	GO:0007611	learning or memory

0.82	GO:0000062	fatty-acyl-CoA binding
0.40	GO:0046983	protein dimerization activity
0.39	GO:0008289	lipid binding
0.35	GO:0030156	benzodiazepine receptor binding
0.32	GO:0016853	isomerase activity
0.32	GO:0016746	transferase activity, transferring acyl groups

0.39	GO:0005794	Golgi apparatus
0.39	GO:0005783	endoplasmic reticulum
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005615	extracellular space
0.35	GO:0031982	vesicle
0.34	GO:0043230	extracellular organelle
0.34	GO:0098793	presynapse
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.33	GO:0005739	mitochondrion

0.32

EC:5

GO:0016853

sp|Q9TR29|CX7A2_CANLF
Cytochrome c oxidase subunit 7A2, mitochondrial (Fragment)
Search

0.90	Cytochrome c oxidase subunit VIIa 1 (Fragment)

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.62	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity

0.78	GO:0005746	mitochondrial respiratory chain
0.37	GO:0070062	extracellular exosome
0.34	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9

GO:0016675

sp|Q9TRM8|RELX_CANLF
Prorelaxin
Search

RLN

0.96	Prorelaxin

0.76	GO:0010469	regulation of receptor activity
0.51	GO:2000344	positive regulation of acrosome reaction
0.51	GO:0001832	blastocyst growth
0.51	GO:0001556	oocyte maturation
0.50	GO:0046326	positive regulation of glucose import
0.49	GO:0030317	flagellated sperm motility
0.49	GO:0050679	positive regulation of epithelial cell proliferation

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|Q9TRY9|BGAL_CANLF
Beta-galactosidase
Search

GLB1

0.40	Beta-galactosidase

0.60	GO:0005975	carbohydrate metabolic process
0.42	GO:0051413	response to cortisone
0.41	GO:1904016	response to Thyroglobulin triiodothyronine
0.36	GO:0044282	small molecule catabolic process
0.36	GO:0042340	keratan sulfate catabolic process
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0006687	glycosphingolipid metabolic process

0.77	GO:0004565	beta-galactosidase activity
0.41	GO:0016936	galactoside binding
0.34	GO:0004308	exo-alpha-sialidase activity
0.33	GO:0005515	protein binding

0.48	GO:0005615	extracellular space
0.48	GO:0005794	Golgi apparatus
0.46	GO:0005773	vacuole
0.36	GO:1903561	extracellular vesicle
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:3.2.1.23

GO:0004565

sp|Q9TRZ8|CX7A1_CANLF
Cytochrome c oxidase subunit 7A1, mitochondrial (Fragment)
Search

0.91	Cytochrome c oxidase subunit 7A1, mitochondrial (Fragment)

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.34	GO:0006879	cellular iron ion homeostasis
0.34	GO:0006826	iron ion transport
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.34	GO:0008199	ferric iron binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005746	mitochondrial respiratory chain
0.35	GO:0070062	extracellular exosome
0.35	GO:0045277	respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:1.9.3

GO:0016676

sp|Q9TS44|CCKN_CANLF
Cholecystokinins
Search

0.49	Cholecystokinin (Fragment)

0.76	GO:0010469	regulation of receptor activity
0.73	GO:0042755	eating behavior
0.70	GO:0001764	neuron migration
0.66	GO:0007409	axonogenesis
0.49	GO:0031667	response to nutrient levels
0.46	GO:0014049	positive regulation of glutamate secretion
0.46	GO:0051901	positive regulation of mitochondrial depolarization
0.46	GO:0051930	regulation of sensory perception of pain
0.46	GO:0001836	release of cytochrome c from mitochondria
0.45	GO:0032096	negative regulation of response to food

0.79

GO:0005179

hormone activity

0.67	GO:0030424	axon
0.66	GO:0005576	extracellular region
0.45	GO:0043204	perikaryon
0.44	GO:0043679	axon terminus
0.43	GO:0030425	dendrite

sp|Q9TSX8|VNN1_CANLF
Pantetheinase
Search

VNN1

0.96	Vascular non-inflammatory molecule 2

0.55	GO:0002544	chronic inflammatory response
0.54	GO:0033089	positive regulation of T cell differentiation in thymus
0.54	GO:0015939	pantothenate metabolic process
0.54	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.52	GO:0002526	acute inflammatory response
0.49	GO:0045087	innate immune response
0.49	GO:0098609	cell-cell adhesion
0.38	GO:0006501	C-terminal protein lipidation
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.68	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.36	GO:0001594	trace-amine receptor activity
0.35	GO:0034235	GPI anchor binding

0.41	GO:0031225	anchored component of membrane
0.41	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005886	plasma membrane
0.36	GO:0035577	azurophil granule membrane
0.30	GO:0016021	integral component of membrane

0.68

EC:3.5.1

GO:0016811

sp|Q9TSZ2|HEY1_CANLF
Hairy/enhancer-of-split related with YRPW motif protein 1
Search

HEY1

0.94	Hairy/enhancer-of-split related with YRPW motif protein 1

0.62	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
0.59	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.58	GO:0045746	negative regulation of Notch signaling pathway
0.58	GO:0007219	Notch signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0048514	blood vessel morphogenesis
0.53	GO:0048646	anatomical structure formation involved in morphogenesis
0.45	GO:0060842	arterial endothelial cell differentiation
0.44	GO:0061027	umbilical cord development
0.44	GO:0035907	dorsal aorta development

0.67	GO:0046983	protein dimerization activity
0.62	GO:0035939	microsatellite binding
0.52	GO:0000989	transcription factor activity, transcription factor binding
0.46	GO:0003700	DNA binding transcription factor activity
0.40	GO:0042802	identical protein binding
0.39	GO:0001102	RNA polymerase II activating transcription factor binding
0.39	GO:0042826	histone deacetylase binding
0.35	GO:0043425	bHLH transcription factor binding

0.61	GO:0005634	nucleus
0.38	GO:0017053	transcriptional repressor complex
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0000785	chromatin
0.35	GO:1902494	catalytic complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9TSZ3|KCNH2_CANLF
Potassium voltage-gated channel subfamily H member 2
Search

KCNH2

0.57	Potassium voltage-gated channel subfamily H member 2

0.75	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0071805	potassium ion transmembrane transport
0.59	GO:0086091	regulation of heart rate by cardiac conduction
0.59	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.58	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.57	GO:0086005	ventricular cardiac muscle cell action potential
0.57	GO:0043267	negative regulation of potassium ion transport
0.56	GO:0086010	membrane depolarization during action potential
0.55	GO:0043268	positive regulation of potassium ion transport
0.55	GO:0055075	potassium ion homeostasis

0.76	GO:0005249	voltage-gated potassium channel activity
0.59	GO:0055131	C3HC4-type RING finger domain binding
0.56	GO:0097110	scaffold protein binding
0.54	GO:0099094	ligand-gated cation channel activity
0.54	GO:0000155	phosphorelay sensor kinase activity
0.53	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0042803	protein homodimerization activity
0.34	GO:0008237	metallopeptidase activity

0.59	GO:1902937	inward rectifier potassium channel complex
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0009986	cell surface
0.37	GO:0005635	nuclear envelope

0.54

EC:2.7.3

GO:0000155

sp|Q9TSZ6|DAG1_CANLF
Dystroglycan
Search

DAG1

0.92	Dystroglycan 1 (Dystrophin-associated glycoprotein 1)

0.85	GO:0007016	cytoskeletal anchoring at plasma membrane
0.61	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis
0.58	GO:0021682	nerve maturation
0.58	GO:0010470	regulation of gastrulation
0.58	GO:0006509	membrane protein ectodomain proteolysis
0.58	GO:0051898	negative regulation of protein kinase B signaling
0.58	GO:0006607	NLS-bearing protein import into nucleus
0.58	GO:0010717	regulation of epithelial to mesenchymal transition
0.57	GO:0034453	microtubule anchoring
0.57	GO:0071679	commissural neuron axon guidance

0.70	GO:0005509	calcium ion binding
0.60	GO:0017166	vinculin binding
0.59	GO:0051393	alpha-actinin binding
0.59	GO:0042169	SH2 domain binding
0.59	GO:0008307	structural constituent of muscle
0.55	GO:0002162	dystroglycan binding
0.52	GO:0015631	tubulin binding
0.52	GO:0003779	actin binding
0.48	GO:0043236	laminin binding
0.37	GO:0043395	heparan sulfate proteoglycan binding

0.83	GO:0016010	dystrophin-associated glycoprotein complex
0.57	GO:0042383	sarcolemma
0.57	GO:0030175	filopodium
0.57	GO:0070938	contractile ring
0.56	GO:0033268	node of Ranvier
0.56	GO:0030027	lamellipodium
0.56	GO:0005604	basement membrane
0.55	GO:0005925	focal adhesion
0.53	GO:0009897	external side of plasma membrane
0.52	GO:0098857	membrane microdomain

sp|Q9TSZ7|GCST_CANLF
Aminomethyltransferase, mitochondrial
Search

AMT

0.56	Aminomethyltransferase

0.73	GO:0006546	glycine catabolic process
0.61	GO:0032259	methylation
0.33	GO:0007049	cell cycle
0.32	GO:0006351	transcription, DNA-templated

0.77	GO:0004047	aminomethyltransferase activity
0.67	GO:0008483	transaminase activity

0.59	GO:0005739	mitochondrion
0.49	GO:0005654	nucleoplasm
0.35	GO:0005960	glycine cleavage complex
0.34	GO:0017053	transcriptional repressor complex
0.30	GO:0016020	membrane

0.77

EC:2.1.2.10

GO:0004047

sp|Q9TT90|ANDR_CANLF
Androgen receptor
Search

0.80	Androgen receptor

0.82	GO:0030521	androgen receptor signaling pathway
0.61	GO:0045720	negative regulation of integrin biosynthetic process
0.57	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903076	regulation of protein localization to plasma membrane
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0045726	positive regulation of integrin biosynthetic process
0.54	GO:0019102	male somatic sex determination

0.84	GO:0004882	androgen receptor activity
0.76	GO:0005496	steroid binding
0.61	GO:0005497	androgen binding
0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.56	GO:0008013	beta-catenin binding
0.55	GO:0070974	POU domain binding
0.52	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0051117	ATPase binding
0.51	GO:0001085	RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.50	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen
0.42	GO:0043234	protein complex
0.40	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|Q9TT99|ATOX1_CANLF
Copper transport protein ATOX1
Search

ATOX1

0.97	Antioxidant 1 copper chaperone

0.66	GO:0030001	metal ion transport
0.52	GO:0006878	cellular copper ion homeostasis
0.43	GO:0006979	response to oxidative stress
0.42	GO:0046907	intracellular transport
0.38	GO:0006801	superoxide metabolic process
0.35	GO:0098662	inorganic cation transmembrane transport
0.35	GO:0019730	antimicrobial humoral response
0.33	GO:0043085	positive regulation of catalytic activity

0.56	GO:0032767	copper-dependent protein binding
0.55	GO:0016531	copper chaperone activity
0.39	GO:0051117	ATPase binding
0.38	GO:0005375	copper ion transmembrane transporter activity
0.35	GO:0047760	butyrate-CoA ligase activity
0.33	GO:0008047	enzyme activator activity
0.32	GO:0008270	zinc ion binding

0.36	GO:0005737	cytoplasm
0.33	GO:0005615	extracellular space
0.32	GO:0044446	intracellular organelle part
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

EC:6.2.1.2

GO:0047760

sp|Q9TTD8|PROP1_CANLF
Homeobox protein prophet of Pit-1
Search

PROP1

0.94	Pituitary specific homeodomain factor

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0048850	hypophysis morphogenesis
0.55	GO:0060126	somatotropin secreting cell differentiation
0.54	GO:0010468	regulation of gene expression
0.54	GO:0021979	hypothalamus cell differentiation
0.51	GO:0060070	canonical Wnt signaling pathway
0.51	GO:0009953	dorsal/ventral pattern formation
0.51	GO:0072359	circulatory system development
0.50	GO:0016477	cell migration

0.62	GO:0043565	sequence-specific DNA binding
0.55	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0035326	enhancer binding
0.51	GO:0008013	beta-catenin binding
0.51	GO:0008022	protein C-terminus binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003682	chromatin binding
0.48	GO:0003690	double-stranded DNA binding
0.40	GO:0001103	RNA polymerase II repressing transcription factor binding

0.61	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.37	GO:0000785	chromatin
0.37	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

0.33

EC:3.5.4.4

GO:0004000

tr|Q9TTF2|Q9TTF2_CANLF
B7-2 protein
Search

CD86

0.94	T-lymphocyte activation antigen CD86

0.42	GO:0034138	toll-like receptor 3 signaling pathway
0.42	GO:0042102	positive regulation of T cell proliferation
0.42	GO:0042113	B cell activation
0.42	GO:0071222	cellular response to lipopolysaccharide
0.41	GO:0002912	negative regulation of lymphocyte anergy
0.41	GO:0002665	negative regulation of T cell tolerance induction
0.41	GO:0006955	immune response
0.40	GO:0051607	defense response to virus
0.40	GO:0002667	regulation of T cell anergy
0.39	GO:0071345	cellular response to cytokine stimulus

0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0104005	hijacked molecular function
0.37	GO:0015026	coreceptor activity
0.37	GO:0005102	receptor binding

0.59	GO:0070062	extracellular exosome
0.41	GO:0009897	external side of plasma membrane
0.36	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|Q9TTI7|PIT1_CANLF
Pituitary-specific positive transcription factor 1
Search

POU1F1

0.60	Pituitary-specific positive transcription factor 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0010468	regulation of gene expression
0.54	GO:0060133	somatotropin secreting cell development
0.54	GO:0001708	cell fate specification
0.53	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.52	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.51	GO:0040018	positive regulation of multicellular organism growth
0.51	GO:1902680	positive regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001105	RNA polymerase II transcription coactivator activity
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0003682	chromatin binding
0.41	GO:0003714	transcription corepressor activity
0.41	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q9TTQ9|GPR83_CANLF
Probable G-protein coupled receptor 83
Search

GPR83

0.85	G protein-coupled receptor 83

0.79	GO:0007218	neuropeptide signaling pathway
0.53	GO:0051384	response to glucocorticoid
0.33	GO:0006302	double-strand break repair
0.32	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.84	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0030145	manganese ion binding
0.33	GO:0004519	endonuclease activity

0.52	GO:0097730	non-motile cilium
0.34	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q9TTW3|TEKT1_CANLF
Tektin-1
Search

TEKT1

0.96

Tektin

0.70	GO:0060294	cilium movement involved in cell motility
0.67	GO:0030317	flagellated sperm motility
0.64	GO:0060271	cilium assembly
0.45	GO:0080154	regulation of fertilization
0.35	GO:0001578	microtubule bundle formation
0.34	GO:0043623	cellular protein complex assembly

0.35

GO:0005515

protein binding

0.68	GO:0036126	sperm flagellum
0.64	GO:0015630	microtubule cytoskeleton
0.51	GO:0005634	nucleus
0.45	GO:0099513	polymeric cytoskeletal fiber
0.38	GO:0002080	acrosomal membrane
0.30	GO:0016021	integral component of membrane

sp|Q9TTY1|TIMP2_CANLF
Metalloproteinase inhibitor 2
Search

TIMP2

0.92	Tissue inhibitor of metalloproteinase 2

0.75	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:1905049	negative regulation of metallopeptidase activity
0.48	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.45	GO:0034097	response to cytokine
0.43	GO:0009725	response to hormone
0.42	GO:0032487	regulation of Rap protein signal transduction
0.42	GO:0030814	regulation of cAMP metabolic process
0.41	GO:0051349	positive regulation of lyase activity
0.41	GO:0031281	positive regulation of cyclase activity
0.41	GO:0045664	regulation of neuron differentiation

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.51	GO:0002020	protease binding
0.42	GO:0005178	integrin binding
0.42	GO:0098770	FBXO family protein binding
0.42	GO:0008270	zinc ion binding
0.37	GO:0008047	enzyme activator activity
0.36	GO:0008237	metallopeptidase activity

0.65	GO:0005576	extracellular region
0.40	GO:0030426	growth cone
0.40	GO:0009986	cell surface
0.40	GO:0043025	neuronal cell body
0.37	GO:1904724	tertiary granule lumen
0.37	GO:0035580	specific granule lumen
0.37	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005634	nucleus

sp|Q9TTY2|FER_CANLF
Tyrosine-protein kinase Fer
Search

FER

0.61	Tyrosine-protein kinase

0.81	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.80	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.77	GO:0030335	positive regulation of cell migration
0.76	GO:0008283	cell proliferation
0.73	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0031532	actin cytoskeleton reorganization
0.61	GO:0050904	diapedesis
0.61	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase
0.60	GO:0036005	response to macrophage colony-stimulating factor
0.60	GO:0033006	regulation of mast cell activation involved in immune response

0.83	GO:0005154	epidermal growth factor receptor binding
0.77	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.57	GO:0008157	protein phosphatase 1 binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008289	lipid binding

0.63	GO:0005856	cytoskeleton
0.56	GO:0030027	lamellipodium
0.55	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.52	GO:0000790	nuclear chromatin
0.52	GO:0030054	cell junction
0.49	GO:0005829	cytosol

0.77

EC:2.7.10.2

GO:0004715

sp|Q9TTY4|MAGBA_CANLF
Melanoma-associated antigen B10
Search

0.96	Melanoma-associated antigen B1

0.44

GO:0005515

protein binding

0.48

GO:0005737

cytoplasm

tr|Q9TU16|Q9TU16_CANLF
Prostaglandin E2 receptor EP4 subtype
Search

PTGER4

0.88	Prostaglandin E receptor 4

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:2000419	regulation of eosinophil extravasation
0.67	GO:2000417	negative regulation of eosinophil migration
0.66	GO:0033624	negative regulation of integrin activation
0.65	GO:0002692	negative regulation of cellular extravasation
0.62	GO:0050728	negative regulation of inflammatory response
0.61	GO:0042093	T-helper cell differentiation
0.60	GO:0050710	negative regulation of cytokine secretion
0.60	GO:0071260	cellular response to mechanical stimulus
0.59	GO:0050715	positive regulation of cytokine secretion

0.85	GO:0004957	prostaglandin E receptor activity
0.34	GO:0005515	protein binding

0.37	GO:0005886	plasma membrane
0.36	GO:0044306	neuron projection terminus
0.36	GO:0043025	neuronal cell body
0.35	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

sp|Q9TU19|NPHP1_CANLF
Nephrocystin-1 (Fragment)
Search

NPHP1

0.97	LOW QUALITY PROTEIN: nephrocystin-1

0.84	GO:1903348	positive regulation of bicellular tight junction assembly
0.54	GO:0048793	pronephros development
0.47	GO:0007283	spermatogenesis
0.46	GO:0035845	photoreceptor cell outer segment organization
0.44	GO:0060041	retina development in camera-type eye
0.44	GO:0030030	cell projection organization
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.42	GO:0003006	developmental process involved in reproduction
0.40	GO:0034613	cellular protein localization
0.37	GO:0070588	calcium ion transmembrane transport

0.41	GO:0005515	protein binding
0.38	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0005528	FK506 binding
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.32	GO:0043021	ribonucleoprotein complex binding

0.72	GO:0031514	motile cilium
0.70	GO:0005911	cell-cell junction
0.45	GO:0097546	ciliary base
0.45	GO:0032391	photoreceptor connecting cilium
0.45	GO:0005912	adherens junction
0.41	GO:0005856	cytoskeleton
0.37	GO:0005891	voltage-gated calcium channel complex
0.37	GO:0005737	cytoplasm
0.35	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005730	nucleolus

0.32

EC:5.2.1.8

GO:0003755

sp|Q9TU31|PTH1R_CANLF
Parathyroid hormone/parathyroid hormone-related peptide receptor
Search

PTH1R

0.92	Parathyroid hormone 1 receptor a

0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0002076	osteoblast development
0.59	GO:0045453	bone resorption
0.58	GO:0030282	bone mineralization
0.58	GO:0019933	cAMP-mediated signaling
0.58	GO:0002062	chondrocyte differentiation
0.56	GO:0048469	cell maturation
0.55	GO:0006874	cellular calcium ion homeostasis
0.54	GO:0008285	negative regulation of cell proliferation

0.86	GO:0004991	parathyroid hormone receptor activity
0.64	GO:0017046	peptide hormone binding
0.59	GO:0043621	protein self-association
0.53	GO:0042803	protein homodimerization activity

0.51	GO:0005886	plasma membrane
0.40	GO:0005903	brush border
0.39	GO:0045177	apical part of cell
0.39	GO:0043235	receptor complex
0.39	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9TU53|CUBN_CANLF
Cubilin
Search

CUBN

0.47

Cubilin

0.50	GO:0042953	lipoprotein transport
0.47	GO:0006898	receptor-mediated endocytosis
0.40	GO:0008203	cholesterol metabolic process
0.39	GO:0042366	cobalamin catabolic process
0.39	GO:0020028	hemoglobin import
0.39	GO:0006508	proteolysis
0.37	GO:0070207	protein homotrimerization
0.37	GO:0007584	response to nutrient
0.36	GO:0001701	in utero embryonic development
0.36	GO:0015889	cobalamin transport

0.69	GO:0005509	calcium ion binding
0.48	GO:0042803	protein homodimerization activity
0.41	GO:0004222	metalloendopeptidase activity
0.38	GO:0031419	cobalamin binding
0.37	GO:0030492	hemoglobin binding
0.36	GO:0004872	receptor activity
0.32	GO:0008168	methyltransferase activity
0.31	GO:0005215	transporter activity

0.52	GO:0005903	brush border
0.51	GO:0016324	apical plasma membrane
0.51	GO:0030139	endocytic vesicle
0.51	GO:0070062	extracellular exosome
0.51	GO:0005905	clathrin-coated pit
0.49	GO:0005768	endosome
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005783	endoplasmic reticulum
0.40	GO:0031253	cell projection membrane
0.40	GO:0005765	lysosomal membrane

0.41

EC:3.4.24

GO:0004222

sp|Q9TU69|GHR_CANLF
Growth hormone receptor
Search

GHR

0.62	Growth hormone receptor

0.79	GO:0019221	cytokine-mediated signaling pathway
0.47	GO:0006897	endocytosis
0.47	GO:0060396	growth hormone receptor signaling pathway
0.44	GO:0046427	positive regulation of JAK-STAT cascade
0.44	GO:0001934	positive regulation of protein phosphorylation
0.43	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.42	GO:0007259	JAK-STAT cascade
0.41	GO:0009410	response to xenobiotic stimulus
0.41	GO:0051094	positive regulation of developmental process
0.41	GO:0033993	response to lipid

0.81	GO:0004896	cytokine receptor activity
0.43	GO:0017046	peptide hormone binding
0.41	GO:0042169	SH2 domain binding
0.40	GO:0019901	protein kinase binding
0.40	GO:0019903	protein phosphatase binding
0.40	GO:0019838	growth factor binding
0.40	GO:0070064	proline-rich region binding
0.38	GO:0042803	protein homodimerization activity

0.54	GO:0036464	cytoplasmic ribonucleoprotein granule
0.50	GO:0005829	cytosol
0.46	GO:0005576	extracellular region
0.46	GO:0005886	plasma membrane
0.43	GO:0070195	growth hormone receptor complex
0.40	GO:0043025	neuronal cell body
0.39	GO:0009986	cell surface
0.37	GO:0031904	endosome lumen
0.37	GO:0019898	extrinsic component of membrane
0.37	GO:0005634	nucleus

sp|Q9TUB3|FOSB_CANLF
Protein fosB
Search

FOSB

0.63	FBJ osteosarcoma oncogene B

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.61	GO:0071277	cellular response to calcium ion
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0051412	response to corticosterone
0.45	GO:0043278	response to morphine
0.44	GO:0032570	response to progesterone
0.44	GO:0051591	response to cAMP
0.44	GO:0007565	female pregnancy
0.43	GO:0009612	response to mechanical stimulus

0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0008134	transcription factor binding

0.60	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.37	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q9TUI5|MT4_CANLF
Metallothionein-4
Search

0.73	Metallothionein-II, hippocampal

0.57	GO:0071294	cellular response to zinc ion
0.51	GO:0045926	negative regulation of growth
0.48	GO:0006875	cellular metal ion homeostasis
0.45	GO:0036018	cellular response to erythropoietin
0.44	GO:0071276	cellular response to cadmium ion
0.41	GO:0036015	response to interleukin-3
0.39	GO:0035690	cellular response to drug
0.37	GO:0071280	cellular response to copper ion
0.36	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.34	GO:0042117	monocyte activation

0.54	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.34	GO:0008144	drug binding

0.50	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005634	nucleus
0.35	GO:0005829	cytosol

sp|Q9TUP7|OX2R_CANLF
Orexin receptor type 2
Search

HCRTR2

0.92	Hypocretin receptor 2

0.84	GO:0007631	feeding behavior
0.82	GO:0022410	circadian sleep/wake cycle process
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0051480	regulation of cytosolic calcium ion concentration
0.62	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.54	GO:0030186	melatonin metabolic process
0.53	GO:1901652	response to peptide
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.51	GO:0032870	cellular response to hormone stimulus

0.87	GO:0016499	orexin receptor activity
0.52	GO:0042277	peptide binding

0.60	GO:0005887	integral component of plasma membrane
0.44	GO:0045177	apical part of cell
0.44	GO:0048471	perinuclear region of cytoplasm

sp|Q9TUX8|NOS3_CANLF
Nitric oxide synthase, endothelial
Search

NOS3

0.72	Nitric oxide synthase

0.84	GO:0006809	nitric oxide biosynthetic process
0.62	GO:0043267	negative regulation of potassium ion transport
0.61	GO:0002026	regulation of the force of heart contraction
0.61	GO:0031284	positive regulation of guanylate cyclase activity
0.61	GO:0014900	muscle hyperplasia
0.61	GO:0014740	negative regulation of muscle hyperplasia
0.61	GO:0014805	smooth muscle adaptation
0.60	GO:0051926	negative regulation of calcium ion transport
0.60	GO:0002028	regulation of sodium ion transport
0.59	GO:0050880	regulation of blood vessel size

0.84	GO:0004517	nitric-oxide synthase activity
0.77	GO:0005516	calmodulin binding
0.70	GO:0010181	FMN binding
0.68	GO:0050661	NADP binding
0.64	GO:0050660	flavin adenine dinucleotide binding
0.62	GO:0020037	heme binding
0.61	GO:0005506	iron ion binding
0.60	GO:0034617	tetrahydrobiopterin binding
0.57	GO:0097110	scaffold protein binding
0.55	GO:0003785	actin monomer binding

0.60	GO:0005901	caveola
0.47	GO:0005634	nucleus
0.46	GO:0042383	sarcolemma
0.45	GO:0033017	sarcoplasmic reticulum membrane
0.45	GO:0030018	Z disc
0.44	GO:0005856	cytoskeleton
0.43	GO:0045202	synapse
0.41	GO:0070013	intracellular organelle lumen
0.40	GO:0005794	Golgi apparatus
0.39	GO:0005739	mitochondrion

0.84

EC:1.14.13.39

GO:0004517

sp|Q9TV56|S10A4_CANLF
Protein S100-A4
Search

sp|Q9TV68|DHDH_CANLF
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
Search

DHDH

0.80	Dihydrodiol dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.49	GO:0042843	D-xylose catabolic process
0.36	GO:0042981	regulation of apoptotic process
0.33	GO:0006091	generation of precursor metabolites and energy
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.54	GO:0016491	oxidoreductase activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0005544	calcium-dependent phospholipid binding

0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.54

EC:1

GO:0016491

sp|Q9TVB8|RPE65_CANLF
Retinoid isomerohydrolase
Search

RPE65

0.97	Retinal Mueller cells isomerohydrolase

0.66	GO:0001523	retinoid metabolic process
0.62	GO:1901827	zeaxanthin biosynthetic process
0.61	GO:0034308	primary alcohol metabolic process
0.61	GO:0034754	cellular hormone metabolic process
0.57	GO:0007468	regulation of rhodopsin gene expression
0.56	GO:0050908	detection of light stimulus involved in visual perception
0.56	GO:0071257	cellular response to electrical stimulus
0.55	GO:0001895	retina homeostasis
0.54	GO:0008286	insulin receptor signaling pathway
0.54	GO:0060042	retina morphogenesis in camera-type eye

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.71	GO:0052885	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
0.68	GO:1901612	cardiolipin binding
0.67	GO:0031210	phosphatidylcholine binding
0.66	GO:0001786	phosphatidylserine binding
0.60	GO:0004744	retinal isomerase activity
0.53	GO:0046872	metal ion binding
0.50	GO:0052884	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
0.36	GO:0050251	retinol isomerase activity
0.34	GO:0005515	protein binding

0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0044297	cell body
0.37	GO:0031090	organelle membrane
0.37	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol

0.75	EC:1.13.11	GO:0016702
0.71	KEGG:R08388	GO:0052885

sp|Q9XS65|PTGDS_CANLF
Prostaglandin-H2 D-isomerase
Search

PTGDS

0.49	Chondrogenesis associated lipocalin

0.72	GO:0046457	prostanoid biosynthetic process
0.71	GO:0006693	prostaglandin metabolic process
0.68	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.65	GO:2000255	negative regulation of male germ cell proliferation
0.40	GO:0051384	response to glucocorticoid
0.38	GO:0044793	negative regulation by host of viral process
0.38	GO:0045071	negative regulation of viral genome replication
0.38	GO:0019369	arachidonic acid metabolic process
0.36	GO:0006303	double-strand break repair via nonhomologous end joining

0.76	GO:0004667	prostaglandin-D synthase activity
0.66	GO:0005501	retinoid binding
0.51	GO:0036094	small molecule binding
0.36	GO:0005515	protein binding
0.35	GO:0043168	anion binding

0.58	GO:0005791	rough endoplasmic reticulum
0.56	GO:0005576	extracellular region
0.53	GO:0031965	nuclear membrane
0.53	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005794	Golgi apparatus
0.38	GO:0031982	vesicle
0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.76	EC:5.3.99.2	GO:0004667
0.76	KEGG:R02266	GO:0004667

sp|Q9XSB8|TPP1_CANLF
Tripeptidyl-peptidase 1
Search

TPP1

0.93	Tripeptidyl peptidase I

0.62	GO:0045453	bone resorption
0.61	GO:0006508	proteolysis
0.58	GO:0050885	neuromuscular process controlling balance
0.57	GO:0007040	lysosome organization
0.56	GO:0007399	nervous system development
0.56	GO:0043171	peptide catabolic process
0.55	GO:0030855	epithelial cell differentiation
0.42	GO:0007626	locomotory behavior
0.36	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0030163	protein catabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.63	GO:0008240	tripeptidyl-peptidase activity
0.49	GO:0046872	metal ion binding
0.37	GO:0042277	peptide binding
0.35	GO:0005515	protein binding

0.56	GO:0005764	lysosome
0.45	GO:0005739	mitochondrion
0.45	GO:0042470	melanosome
0.37	GO:0070062	extracellular exosome
0.36	GO:0005775	vacuolar lumen
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:3.4.21

GO:0004252

sp|Q9XSI1|CTLA4_CANLF
Cytotoxic T-lymphocyte protein 4
Search

CTLA4

0.97	Soluble form of cytotoxic T-lymphocyte antigen 4

0.74	GO:0006955	immune response
0.69	GO:0045590	negative regulation of regulatory T cell differentiation
0.67	GO:0030889	negative regulation of B cell proliferation
0.65	GO:0050853	B cell receptor signaling pathway
0.60	GO:0043065	positive regulation of apoptotic process
0.51	GO:0006974	cellular response to DNA damage stimulus
0.43	GO:0042130	negative regulation of T cell proliferation
0.40	GO:0050777	negative regulation of immune response
0.36	GO:0031295	T cell costimulation

0.37	GO:0005515	protein binding
0.36	GO:0004872	receptor activity

0.64	GO:0045334	clathrin-coated endocytic vesicle
0.62	GO:0009897	external side of plasma membrane
0.62	GO:0098636	protein complex involved in cell adhesion
0.60	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0005794	Golgi apparatus
0.54	GO:0005887	integral component of plasma membrane

sp|Q9XSJ7|CO1A1_CANLF
Collagen alpha-1(I) chain
Search

COL1A1

0.84	Collagen type II alpha 1 chain

0.61	GO:0030199	collagen fibril organization
0.60	GO:0001958	endochondral ossification
0.60	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.59	GO:0032964	collagen biosynthetic process
0.59	GO:0034505	tooth mineralization
0.59	GO:0048706	embryonic skeletal system development
0.59	GO:0043589	skin morphogenesis
0.58	GO:0007605	sensory perception of sound
0.58	GO:0001957	intramembranous ossification
0.58	GO:0060346	bone trabecula formation

0.78	GO:0005201	extracellular matrix structural constituent
0.63	GO:0048407	platelet-derived growth factor binding
0.56	GO:0002020	protease binding
0.53	GO:0042802	identical protein binding
0.46	GO:0042289	MHC class II protein binding
0.37	GO:0046872	metal ion binding

0.72	GO:0005581	collagen trimer
0.62	GO:0098643	banded collagen fibril
0.55	GO:0005615	extracellular space
0.43	GO:0005604	basement membrane
0.40	GO:0005737	cytoplasm
0.38	GO:0097708	intracellular vesicle
0.38	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q9XSR0|IL18_CANLF
Interleukin-18
Search

IL18

0.97	Interleukin-18

0.80	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.64	GO:0042095	interferon-gamma biosynthetic process
0.61	GO:0035655	interleukin-18-mediated signaling pathway
0.61	GO:0051140	regulation of NK T cell proliferation
0.61	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.61	GO:0032819	positive regulation of natural killer cell proliferation
0.61	GO:0051135	positive regulation of NK T cell activation
0.61	GO:0042104	positive regulation of activated T cell proliferation

0.80

GO:0005125

cytokine activity

0.73	GO:0005615	extracellular space
0.38	GO:0005622	intracellular
0.37	GO:1903561	extracellular vesicle
0.35	GO:0016324	apical plasma membrane

sp|Q9XSR1|ZN252_CANLF
Zinc finger protein 252
Search

0.58	Zinc finger protein 135

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.36	GO:0007010	cytoskeleton organization
0.36	GO:0022604	regulation of cell morphogenesis
0.36	GO:0045321	leukocyte activation
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0030154	cell differentiation
0.35	GO:0007275	multicellular organism development

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.47	GO:0042802	identical protein binding
0.42	GO:0003700	DNA binding transcription factor activity
0.35	GO:0046982	protein heterodimerization activity

0.43	GO:0005622	intracellular
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0044422	organelle part
0.34	GO:0043228	non-membrane-bounded organelle
0.33	GO:0005886	plasma membrane

sp|Q9XSR3|RBM47_CANLF
RNA-binding protein 47
Search

RBM47

0.96	LOW QUALITY PROTEIN: RNA-binding protein 47

0.86	GO:0016554	cytidine to uridine editing
0.53	GO:0002244	hematopoietic progenitor cell differentiation
0.47	GO:2000742	regulation of anterior head development
0.43	GO:0060322	head development
0.34	GO:0016567	protein ubiquitination
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0046872	metal ion binding

0.44	GO:0005634	nucleus
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0019013	viral nucleocapsid
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.34

KEGG:R03876

GO:0004842

sp|Q9XST2|GTR4_CANLF
Solute carrier family 2, facilitated glucose transporter member 4 (Fragment)
Search

0.64	Solute carrier family 2, facilitated glucose transporter member 4 (Fragment)

0.70	GO:1904659	glucose transmembrane transport
0.67	GO:0032869	cellular response to insulin stimulus
0.56	GO:0010021	amylopectin biosynthetic process
0.54	GO:0050873	brown fat cell differentiation
0.53	GO:0046323	glucose import
0.52	GO:0071356	cellular response to tumor necrosis factor
0.51	GO:0071470	cellular response to osmotic stress
0.51	GO:0042593	glucose homeostasis
0.38	GO:0045471	response to ethanol
0.38	GO:0071456	cellular response to hypoxia

0.70	GO:0005355	glucose transmembrane transporter activity
0.39	GO:0005536	glucose binding
0.37	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.36	GO:0009679	hexose:proton symporter activity
0.35	GO:0005515	protein binding

0.56	GO:0032593	insulin-responsive compartment
0.53	GO:0042383	sarcolemma
0.52	GO:0030140	trans-Golgi network transport vesicle
0.51	GO:0070062	extracellular exosome
0.51	GO:0009897	external side of plasma membrane
0.51	GO:0045121	membrane raft
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0030659	cytoplasmic vesicle membrane
0.49	GO:0005768	endosome
0.47	GO:0005887	integral component of plasma membrane

sp|Q9XST5|MT2_CANLF
Metallothionein-2
Search

0.75	Metallothionein-I, hippocampal

0.65	GO:0071294	cellular response to zinc ion
0.56	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.47	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.41	GO:0035690	cellular response to drug
0.40	GO:0046688	response to copper ion
0.39	GO:0007263	nitric oxide mediated signal transduction
0.39	GO:0097501	stress response to metal ion
0.38	GO:0006882	cellular zinc ion homeostasis

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.55	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.35	GO:0005829	cytosol

sp|Q9XSU0|RL13A_CANLF
60S ribosomal protein L13a
Search

RPL13A

0.92	Ribosomal protein 13A, pseudogene 1

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:1901194	negative regulation of formation of translation preinitiation complex
0.44	GO:0071346	cellular response to interferon-gamma
0.39	GO:0010469	regulation of receptor activity
0.38	GO:0048246	macrophage chemotaxis
0.38	GO:0060425	lung morphogenesis
0.37	GO:0032496	response to lipopolysaccharide

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0003729	mRNA binding
0.40	GO:0005125	cytokine activity
0.35	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.71	GO:0015934	large ribosomal subunit
0.49	GO:0097452	GAIT complex
0.45	GO:0022626	cytosolic ribosome
0.36	GO:0005925	focal adhesion
0.35	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.2.1

GO:0016620

sp|Q9XSU3|RL23_CANLF
60S ribosomal protein L23
Search

RPL23

0.64	Ribosomal protein L23

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.47	GO:0072717	cellular response to actinomycin D
0.46	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.46	GO:1901798	positive regulation of signal transduction by p53 class mediator
0.46	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.45	GO:0071157	negative regulation of cell cycle arrest
0.45	GO:0071158	positive regulation of cell cycle arrest

0.62	GO:0003735	structural constituent of ribosome
0.47	GO:1990948	ubiquitin ligase inhibitor activity
0.46	GO:0001223	transcription coactivator binding
0.44	GO:0070180	large ribosomal subunit rRNA binding
0.43	GO:0031625	ubiquitin protein ligase binding

0.59	GO:0005840	ribosome
0.45	GO:0005730	nucleolus
0.43	GO:0044445	cytosolic part
0.41	GO:0005654	nucleoplasm
0.38	GO:0043234	protein complex
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9XSU4|RS11_CANLF
40S ribosomal protein S11
Search

RPS11

0.60	Ribosomal protein S11

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0010469	regulation of receptor activity
0.35	GO:0001649	osteoblast differentiation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0019843	rRNA binding
0.36	GO:0005125	cytokine activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.61	GO:0005840	ribosome
0.51	GO:0044445	cytosolic part
0.44	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.2.1

GO:0016620

sp|Q9XSU7|RL27_CANLF
60S ribosomal protein L27
Search

RPL27

0.75	60S ribosomal protein L27

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.44	GO:0030218	erythrocyte differentiation
0.42	GO:0016072	rRNA metabolic process
0.42	GO:0042254	ribosome biogenesis
0.35	GO:1904044	response to aldosterone
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.47	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.44	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.32

EC:3

GO:0016787

sp|Q9XSV3|TMM47_CANLF
Transmembrane protein 47
Search

TMEM47

0.96	transmembrane protein 47

0.33

GO:0005515

protein binding

0.49	GO:0030054	cell junction
0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q9XSV4|Q9XSV4_CANLF
CE10 protein
Search

sp|Q9XSV5|LY65C_CANLF
Lymphocyte antigen 6 complex locus protein G5c
Search

LY6G5C

0.97	Lymphocyte antigen 6 family member G5C

0.71

GO:0051260

protein homooligomerization

0.68	GO:0042802	identical protein binding
0.34	GO:0016787	hydrolase activity

0.75	GO:0009897	external side of plasma membrane
0.55	GO:0043234	protein complex
0.45	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3

GO:0016787

sp|Q9XSW8|GLHA_CANLF
Glycoprotein hormones alpha chain
Search

CGA

0.93	Glycoprotein hormones alpha chain

0.76	GO:0010469	regulation of receptor activity
0.54	GO:0046884	follicle-stimulating hormone secretion
0.54	GO:0032275	luteinizing hormone secretion
0.53	GO:0006590	thyroid hormone generation
0.52	GO:0030878	thyroid gland development
0.51	GO:0046621	negative regulation of organ growth
0.50	GO:0008406	gonad development
0.49	GO:0048589	developmental growth
0.47	GO:0032870	cellular response to hormone stimulus
0.34	GO:0006702	androgen biosynthetic process

0.79	GO:0005179	hormone activity
0.44	GO:0046982	protein heterodimerization activity
0.35	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q9XT54|PDE6D_CANLF
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Search

PDE6D

0.91	Phosphodiesterase 6D

0.78	GO:0007601	visual perception
0.75	GO:0034260	negative regulation of GTPase activity
0.43	GO:0001822	kidney development
0.42	GO:0001654	eye development

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.78	GO:0005095	GTPase inhibitor activity
0.71	GO:0017137	Rab GTPase binding

0.64	GO:0031410	cytoplasmic vesicle
0.61	GO:0005829	cytosol

0.80

EC:3.1.4.17

GO:0004114

sp|Q9XT60|SRY_CANLF
Sex-determining region Y protein
Search

SRY

0.82	Sex-determining region Y protein (Fragment)

0.85	GO:0030238	male sex determination
0.81	GO:0007548	sex differentiation
0.72	GO:0030154	cell differentiation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:2000020	positive regulation of male gonad development
0.36	GO:0051254	positive regulation of RNA metabolic process
0.36	GO:0010557	positive regulation of macromolecule biosynthetic process

0.79	GO:0005516	calmodulin binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.36	GO:0008134	transcription factor binding

0.80	GO:0016607	nuclear speck
0.38	GO:0005737	cytoplasm

sp|Q9XT74|NRAM1_CANLF
Natural resistance-associated macrophage protein 1
Search

SLC11A1

0.96	Natural resistance-associated macrophages protein 1

0.66	GO:0030001	metal ion transport
0.59	GO:0045342	MHC class II biosynthetic process
0.59	GO:0032632	interleukin-3 production
0.58	GO:0002309	T cell proliferation involved in immune response
0.58	GO:0006876	cellular cadmium ion homeostasis
0.58	GO:0002606	positive regulation of dendritic cell antigen processing and presentation
0.57	GO:0032623	interleukin-2 production
0.57	GO:0060586	multicellular organismal iron ion homeostasis
0.57	GO:0002369	T cell cytokine production
0.57	GO:0043091	L-arginine import

0.69	GO:0046873	metal ion transmembrane transporter activity
0.50	GO:0015491	cation:cation antiporter activity
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0015299	solute:proton antiporter activity
0.34	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.33	GO:0016791	phosphatase activity

0.57	GO:0070821	tertiary granule membrane
0.56	GO:0030670	phagocytic vesicle membrane
0.52	GO:0005770	late endosome
0.52	GO:0005764	lysosome
0.51	GO:0010008	endosome membrane
0.41	GO:0005886	plasma membrane
0.36	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0009986	cell surface
0.34	GO:0005635	nuclear envelope
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q9XT82|PE2R2_CANLF
Prostaglandin E2 receptor EP2 subtype
Search

PTGER2

0.94	Prostacyclin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:0071379	cellular response to prostaglandin stimulus
0.63	GO:0034695	response to prostaglandin E
0.60	GO:1901655	cellular response to ketone
0.60	GO:0097306	cellular response to alcohol
0.57	GO:0019933	cAMP-mediated signaling
0.57	GO:0032570	response to progesterone
0.56	GO:0032496	response to lipopolysaccharide
0.53	GO:0042127	regulation of cell proliferation
0.44	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway

0.84	GO:0004955	prostaglandin receptor activity
0.42	GO:0004960	thromboxane receptor activity
0.32	GO:0005515	protein binding

0.41	GO:0005886	plasma membrane
0.39	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q9ZZ56|NU6M_CANLF
NADH-ubiquinone oxidoreductase chain 6
Search

ND6

0.49	NADH-ubiquinone oxidoreductase chain 6

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.34	GO:0070469	respiratory chain
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:1.6.5.3

GO:0008137

sp|Q9ZZ57|NU5M_CANLF
NADH-ubiquinone oxidoreductase chain 5
Search

ND5

0.48	NADH-ubiquinone oxidoreductase chain 5

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0030964	NADH dehydrogenase complex
0.34	GO:0098798	mitochondrial protein complex
0.33	GO:1990204	oxidoreductase complex
0.33	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

EC:1.6.5.3

GO:0008137

sp|Q9ZZ58|NU4M_CANLF
NADH-ubiquinone oxidoreductase chain 4
Search

ND4

0.45	NADH-ubiquinone oxidoreductase chain 4

0.75

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.36	GO:0045271	respiratory chain complex I
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.69

EC:1.6.5.3

GO:0008137

sp|Q9ZZ59|NU4LM_CANLF
NADH-ubiquinone oxidoreductase chain 4L
Search

ND4L

0.50	NADH-ubiquinone oxidoreductase chain 4L

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.43	GO:0070469	respiratory chain
0.43	GO:0031967	organelle envelope
0.42	GO:0031090	organelle membrane
0.37	GO:0030964	NADH dehydrogenase complex
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

EC:1.6.5.3

GO:0008137

sp|Q9ZZ60|NU3M_CANLF
NADH-ubiquinone oxidoreductase chain 3
Search

ND3

0.47	NADH-ubiquinone oxidoreductase chain 3

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.38	GO:0030964	NADH dehydrogenase complex
0.37	GO:0098798	mitochondrial protein complex
0.36	GO:1990204	oxidoreductase complex
0.35	GO:0098796	membrane protein complex
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:1.6.5.3

GO:0008137

sp|Q9ZZ61|COX3_CANLF
Cytochrome c oxidase subunit 3
Search

COX3

0.44	Cytochrome c oxidase subunit 3

0.76	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport
0.38	GO:0008535	respiratory chain complex IV assembly

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.37	GO:0045277	respiratory chain complex IV
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|Q9ZZ62|ATP6_CANLF
ATP synthase subunit a
Search

ATP6

0.43	ATP synthase subunit a

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016887	ATPase activity

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.38	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.34

EC:3.6.1.3

GO:0016887

sp|Q9ZZ63|ATP8_CANLF
ATP synthase protein 8
Search

ATP8

0.48	ATP synthase protein 8

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.34	GO:0055093	response to hyperoxia
0.32	GO:0055114	oxidation-reduction process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016887	ATPase activity
0.32	GO:0016491	oxidoreductase activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.34

EC:3.6.1.3

GO:0016887

sp|Q9ZZ64|COX1_CANLF
Cytochrome c oxidase subunit 1
Search

COX1

0.43	Cytochrome c oxidase subunit 1

0.64	GO:0006119	oxidative phosphorylation
0.64	GO:0009060	aerobic respiration
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0020037	heme binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.63	GO:0005506	iron ion binding
0.62	GO:0009055	electron transfer activity

0.74	GO:0045277	respiratory chain complex IV
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.38	GO:0098798	mitochondrial protein complex
0.37	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|Q9ZZ65|NU2M_CANLF
NADH-ubiquinone oxidoreductase chain 2
Search

ND2

0.44	NADH-ubiquinone oxidoreductase chain 2

0.75	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.35	GO:0072593	reactive oxygen species metabolic process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.36	GO:0030964	NADH dehydrogenase complex
0.35	GO:0098798	mitochondrial protein complex
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

EC:1.6.5.3

GO:0008137

tr|R4GDM1|R4GDM1_CANLF
EGF domain-specific O-linked N-acetylglucosamine transferase
Search

EOGT

0.96	EGF domain-specific O-linked N-acetylglucosamine transferase

0.56

GO:0006493

protein O-linked glycosylation

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.44	GO:0140096	catalytic activity, acting on a protein

0.44	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.65

EC:2.4

GO:0016757

tr|S4R144|S4R144_CANLF
Single-stranded DNA cytosine deaminase
Search

AICDA

0.96	Single-stranded DNA cytosine deaminase

0.56	GO:0016445	somatic diversification of immunoglobulins
0.55	GO:0090310	negative regulation of methylation-dependent chromatin silencing
0.55	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response
0.55	GO:0009972	cytidine deamination
0.54	GO:0002312	B cell activation involved in immune response
0.54	GO:0097752	regulation of DNA stability
0.54	GO:0002566	somatic diversification of immune receptors via somatic mutation
0.53	GO:0071222	cellular response to lipopolysaccharide
0.53	GO:0016444	somatic cell DNA recombination
0.52	GO:0080111	DNA demethylation

0.71	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.63	GO:0008270	zinc ion binding
0.51	GO:0019239	deaminase activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0042802	identical protein binding

0.49	GO:0000178	exosome (RNase complex)
0.43	GO:0005634	nucleus
0.39	GO:0001527	microfibril
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.71

EC:3.5.4

GO:0016814

tr|T1ECS1|T1ECS1_CANLF
Alpha-(1,3)-fucosyltransferase 9
Search

FUT9

0.74	Fucosyltransferase 9

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.38	GO:0007399	nervous system development
0.35	GO:0042355	L-fucose catabolic process

0.81

GO:0008417

fucosyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.4.1

GO:0008417

tr|U3JA26|U3JA26_CANLF
Small integral membrane protein 12
Search

SMIM12

0.97	Small integral membrane protein 12-A

0.30

GO:0044425

membrane part

tr|Z4YHH2|Z4YHH2_CANLF
Tripeptidyl-peptidase 1
Search

TPP1

0.93	Tripeptidyl peptidase I

0.62	GO:0045453	bone resorption
0.61	GO:0006508	proteolysis
0.58	GO:0050885	neuromuscular process controlling balance
0.57	GO:0007040	lysosome organization
0.56	GO:0007399	nervous system development
0.56	GO:0043171	peptide catabolic process
0.55	GO:0030855	epithelial cell differentiation
0.42	GO:0007626	locomotory behavior
0.36	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0030163	protein catabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.63	GO:0008240	tripeptidyl-peptidase activity
0.49	GO:0046872	metal ion binding
0.37	GO:0042277	peptide binding
0.35	GO:0005515	protein binding

0.56	GO:0005764	lysosome
0.45	GO:0005739	mitochondrion
0.45	GO:0042470	melanosome
0.37	GO:0070062	extracellular exosome
0.36	GO:0005775	vacuolar lumen
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:3.4.21

GO:0004252

tr|Z4YHI2|Z4YHI2_CANLF
Uncharacterized protein
Search

ACTB

0.84	Actin cytoplasmic 1

0.53	GO:0098974	postsynaptic actin cytoskeleton organization
0.52	GO:0072749	cellular response to cytochalasin B
0.49	GO:0032091	negative regulation of protein binding
0.46	GO:0045214	sarcomere organization
0.46	GO:0071346	cellular response to interferon-gamma
0.44	GO:0048870	cell motility
0.39	GO:0070527	platelet aggregation
0.39	GO:0001895	retina homeostasis
0.37	GO:0021762	substantia nigra development
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.53	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0030957	Tat protein binding
0.51	GO:0050998	nitric-oxide synthase binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008144	drug binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019894	kinesin binding
0.49	GO:0005522	profilin binding

0.75	GO:0097433	dense body
0.69	GO:0005925	focal adhesion
0.60	GO:0005856	cytoskeleton
0.54	GO:0043209	myelin sheath
0.50	GO:0005886	plasma membrane
0.48	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0070062	extracellular exosome
0.46	GO:0044448	cell cortex part
0.45	GO:0005829	cytosol