Queries 19001 to 20000

GO:0004252

tr|J9PB64|J9PB64_CANLF
Uncharacterized protein
Search

TOR1AIP2

0.84	Torsin-1A-interacting protein 2

0.69	GO:0090435	protein localization to nuclear envelope
0.65	GO:0007029	endoplasmic reticulum organization
0.64	GO:0032781	positive regulation of ATPase activity

0.67	GO:0051117	ATPase binding
0.64	GO:0001671	ATPase activator activity

0.56	GO:0005783	endoplasmic reticulum
0.53	GO:0005635	nuclear envelope
0.51	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.49	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.30	GO:0044425	membrane part

tr|J9PB65|J9PB65_CANLF
Uncharacterized protein
Search

BMF

0.97	Bcl-2-modifying factor

0.78	GO:0006915	apoptotic process
0.55	GO:0034644	cellular response to UV
0.52	GO:0043065	positive regulation of apoptotic process
0.51	GO:0010507	negative regulation of autophagy
0.46	GO:0032464	positive regulation of protein homooligomerization
0.45	GO:1904093	negative regulation of autophagic cell death
0.45	GO:0090199	regulation of release of cytochrome c from mitochondria
0.44	GO:0010822	positive regulation of mitochondrion organization
0.42	GO:0009967	positive regulation of signal transduction
0.41	GO:2001234	negative regulation of apoptotic signaling pathway

0.38	GO:0030942	endoplasmic reticulum signal peptide binding
0.37	GO:0005515	protein binding
0.37	GO:0008312	7S RNA binding

0.42	GO:0016459	myosin complex
0.42	GO:0001669	acrosomal vesicle
0.38	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.38	GO:0005741	mitochondrial outer membrane
0.36	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane

tr|J9PB66|J9PB66_CANLF
Uncharacterized protein
Search

ZNF684

0.72	Zinc finger imprinted 3

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:1902679	negative regulation of RNA biosynthetic process

0.50	GO:0046872	metal ion binding
0.49	GO:0003676	nucleic acid binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0046982	protein heterodimerization activity

0.42	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.33	GO:0043233	organelle lumen
0.33	GO:0043228	non-membrane-bounded organelle

tr|J9PB67|J9PB67_CANLF
Uncharacterized protein
Search

tr|J9PB70|J9PB70_CANLF
Uncharacterized protein
Search

0.66	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0009653	anatomical structure morphogenesis
0.47	GO:0006351	transcription, DNA-templated
0.46	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0030154	cell differentiation
0.37	GO:0008283	cell proliferation
0.37	GO:0016477	cell migration

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0003700	DNA binding transcription factor activity
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.53	GO:0016235	aggresome
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0015630	microtubule cytoskeleton
0.45	GO:0044446	intracellular organelle part

tr|J9PB72|J9PB72_CANLF
Uncharacterized protein
Search

NDUFS4

0.90	Mitochondrial NADH dehydrogenase Fe-S protein 4

0.61	GO:0022900	electron transport chain
0.57	GO:0048146	positive regulation of fibroblast proliferation
0.56	GO:0051591	response to cAMP
0.56	GO:0032981	mitochondrial respiratory chain complex I assembly
0.55	GO:0019933	cAMP-mediated signaling
0.53	GO:0007420	brain development
0.50	GO:0072593	reactive oxygen species metabolic process
0.49	GO:0001932	regulation of protein phosphorylation
0.45	GO:0045333	cellular respiration
0.33	GO:0006119	oxidative phosphorylation

0.67

GO:0016651

oxidoreductase activity, acting on NAD(P)H

0.56	GO:0045271	respiratory chain complex I
0.55	GO:0005746	mitochondrial respiratory chain
0.53	GO:0098800	inner mitochondrial membrane protein complex
0.50	GO:1990204	oxidoreductase complex

0.67

EC:1.6

GO:0016651

tr|J9PB73|J9PB73_CANLF
Uncharacterized protein
Search

tr|J9PB75|J9PB75_CANLF
Uncharacterized protein
Search

0.44	GO:0009247	glycolipid biosynthetic process
0.32	GO:0005975	carbohydrate metabolic process

0.49	GO:0050694	galactose 3-O-sulfotransferase activity
0.32	GO:0030246	carbohydrate binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.31	GO:0003677	DNA binding

0.73	GO:0005815	microtubule organizing center
0.56	GO:0043231	intracellular membrane-bounded organelle
0.54	GO:0005886	plasma membrane
0.42	GO:0012505	endomembrane system
0.38	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:2.8.2

GO:0050694

tr|J9PB76|J9PB76_CANLF
Acyl-coenzyme A oxidase
Search

ACOXL

0.39	Acyl-coenzyme A oxidase

0.75	GO:0006635	fatty acid beta-oxidation
0.34	GO:0051791	medium-chain fatty acid metabolic process

0.81	GO:0003997	acyl-CoA oxidase activity
0.69	GO:0071949	FAD binding
0.46	GO:0003995	acyl-CoA dehydrogenase activity
0.35	GO:0004085	butyryl-CoA dehydrogenase activity

0.74	GO:0042579	microbody
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

0.81	EC:1.3.3.6	GO:0003997
0.35	KEGG:R01178	GO:0004085

tr|J9PB77|J9PB77_CANLF
Uncharacterized protein
Search

MYCBP2

0.73	MYC-binding protein 2, E3 ubiquitin protein ligase

0.47	GO:0021785	branchiomotor neuron axon guidance
0.46	GO:0021952	central nervous system projection neuron axonogenesis
0.45	GO:0042177	negative regulation of protein catabolic process
0.43	GO:0051493	regulation of cytoskeleton organization
0.42	GO:0032880	regulation of protein localization
0.36	GO:0016567	protein ubiquitination
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.61	GO:0016874	ligase activity
0.43	GO:0042803	protein homodimerization activity
0.34	GO:0046872	metal ion binding
0.33	GO:0016740	transferase activity

0.44	GO:0030424	axon
0.41	GO:0015630	microtubule cytoskeleton
0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.61

GO:0016874

tr|J9PB79|J9PB79_CANLF
Uncharacterized protein
Search

0.43	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|J9PB80|J9PB80_CANLF
Uncharacterized protein
Search

URAD

0.51	Parahox neighbor B

0.84	GO:0019428	allantoin biosynthetic process
0.43	GO:0019628	urate catabolic process
0.41	GO:0006144	purine nucleobase metabolic process
0.32	GO:0005975	carbohydrate metabolic process
0.32	GO:0006355	regulation of transcription, DNA-templated

0.50	GO:0016831	carboxy-lyase activity
0.38	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
0.35	GO:0033971	hydroxyisourate hydrolase activity
0.34	GO:0004099	chitin deacetylase activity
0.34	GO:0050538	N-carbamoyl-L-amino-acid hydrolase activity
0.33	GO:0043565	sequence-specific DNA binding

0.41	GO:0005777	peroxisome
0.32	GO:0005634	nucleus

0.50	EC:4.1.1	GO:0016831
0.35	KEGG:R06601	GO:0033971

tr|J9PB81|J9PB81_CANLF
Uncharacterized protein
Search

CTSG

0.94	Endogenous granzyme B

0.65	GO:0001909	leukocyte mediated cytotoxicity
0.62	GO:0002443	leukocyte mediated immunity
0.61	GO:0006508	proteolysis
0.60	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.56	GO:0006952	defense response
0.55	GO:0006955	immune response
0.53	GO:0051851	modification by host of symbiont morphology or physiology
0.52	GO:0044130	negative regulation of growth of symbiont in host
0.51	GO:0009620	response to fungus
0.51	GO:0051883	killing of cells in other organism involved in symbiotic interaction

0.69	GO:0004252	serine-type endopeptidase activity
0.50	GO:0008201	heparin binding
0.35	GO:0005515	protein binding
0.34	GO:0042277	peptide binding

0.64	GO:0030141	secretory granule
0.49	GO:0010494	cytoplasmic stress granule
0.48	GO:0031012	extracellular matrix
0.47	GO:0005615	extracellular space
0.40	GO:0005886	plasma membrane
0.36	GO:0005764	lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.35	GO:1903561	extracellular vesicle
0.34	GO:0005882	intermediate filament

0.69

GO:0004252

tr|J9PB82|J9PB82_CANLF
Uncharacterized protein
Search

BRD3

0.91	Bromodomain containing 3

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0002574	thrombocyte differentiation

0.84	GO:0140033	acetylation-dependent protein binding
0.79	GO:0042393	histone binding
0.77	GO:0003682	chromatin binding

tr|J9PB83|J9PB83_CANLF
Uncharacterized protein
Search

FABP4

0.84	Adipocyte fatty acid-binding protein 4

0.72	GO:0050727	regulation of inflammatory response
0.61	GO:0050872	white fat cell differentiation
0.61	GO:0071285	cellular response to lithium ion
0.61	GO:0042632	cholesterol homeostasis
0.58	GO:0050873	brown fat cell differentiation
0.58	GO:0001816	cytokine production
0.57	GO:0071356	cellular response to tumor necrosis factor
0.56	GO:0032103	positive regulation of response to external stimulus
0.56	GO:0006469	negative regulation of protein kinase activity
0.56	GO:0031349	positive regulation of defense response

0.79	GO:0005504	fatty acid binding
0.41	GO:0008092	cytoskeletal protein binding

0.46	GO:0043209	myelin sheath
0.43	GO:0005615	extracellular space
0.38	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.37	GO:0005811	lipid droplet
0.37	GO:1903561	extracellular vesicle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

tr|J9PB86|J9PB86_CANLF
Uncharacterized protein
Search

BLM

0.91	Bloom syndrome RecQ like helicase

0.69	GO:0032508	DNA duplex unwinding
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.64	GO:0006281	DNA repair
0.62	GO:0072757	cellular response to camptothecin
0.61	GO:0061820	telomeric D-loop disassembly
0.61	GO:0072711	cellular response to hydroxyurea
0.60	GO:0035786	protein complex oligomerization
0.60	GO:0044806	G-quadruplex DNA unwinding
0.59	GO:0010165	response to X-ray

0.79	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.63	GO:0061749	forked DNA-dependent helicase activity
0.62	GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding
0.62	GO:0061821	telomeric D-loop binding
0.60	GO:0000405	bubble DNA binding
0.60	GO:0051880	G-quadruplex DNA binding
0.59	GO:0036310	annealing helicase activity
0.59	GO:0000403	Y-form DNA binding
0.59	GO:0000400	four-way junction DNA binding
0.58	GO:0002039	p53 binding

0.60	GO:0005634	nucleus
0.55	GO:0000781	chromosome, telomeric region
0.53	GO:0000793	condensed chromosome
0.49	GO:0005829	cytosol
0.49	GO:0070013	intracellular organelle lumen
0.38	GO:0005657	replication fork
0.30	GO:0016020	membrane

0.33

GO:0004674

tr|J9PB87|J9PB87_CANLF
Uncharacterized protein
Search

ZC3HC1

0.90	Nuclear-interacting partner of ALK

0.52	GO:1901099	negative regulation of signal transduction in absence of ligand
0.51	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.50	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.42	GO:0016567	protein ubiquitination
0.41	GO:0051301	cell division
0.41	GO:0007049	cell cycle

0.63	GO:0008270	zinc ion binding
0.49	GO:0019901	protein kinase binding

0.61	GO:0005634	nucleus
0.45	GO:0012505	endomembrane system
0.43	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane

tr|J9PB88|J9PB88_CANLF
Flap endonuclease 1
Search

FEN1

0.64	Flap endonuclease 1

0.81	GO:0043137	DNA replication, removal of RNA primer
0.69	GO:0006284	base-excision repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.58	GO:0045876	positive regulation of sister chromatid cohesion
0.39	GO:0007613	memory
0.36	GO:0033260	nuclear DNA replication
0.36	GO:0009411	response to UV
0.35	GO:0006302	double-strand break repair
0.34	GO:0098502	DNA dephosphorylation
0.34	GO:0000734	gene conversion at mating-type locus, DNA repair synthesis

0.79	GO:0017108	5'-flap endonuclease activity
0.74	GO:0008409	5'-3' exonuclease activity
0.62	GO:0000287	magnesium ion binding
0.55	GO:0003677	DNA binding
0.50	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.36	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.35	GO:0030145	manganese ion binding
0.34	GO:0008297	single-stranded DNA exodeoxyribonuclease activity
0.33	GO:0005515	protein binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.71	GO:0005730	nucleolus
0.68	GO:0005654	nucleoplasm
0.60	GO:0005739	mitochondrion
0.54	GO:0000784	nuclear chromosome, telomeric region
0.44	GO:0043234	protein complex
0.34	GO:0035861	site of double-strand break
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.50

EC:3.1.26.4

GO:0004523

tr|J9PB90|J9PB90_CANLF
Uncharacterized protein
Search

GLUL

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.49	GO:0008283	cell proliferation
0.49	GO:0009749	response to glucose
0.47	GO:0009267	cellular response to starvation
0.39	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.39	GO:0019676	ammonia assimilation cycle
0.39	GO:0032024	positive regulation of insulin secretion
0.38	GO:0050679	positive regulation of epithelial cell proliferation
0.38	GO:0051260	protein homooligomerization
0.35	GO:0001504	neurotransmitter uptake

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042802	identical protein binding
0.43	GO:0004351	glutamate decarboxylase activity
0.40	GO:0016595	glutamate binding
0.39	GO:0045503	dynein light chain binding
0.37	GO:0030145	manganese ion binding
0.36	GO:0000287	magnesium ion binding

0.51	GO:0097386	glial cell projection
0.48	GO:0043209	myelin sheath
0.47	GO:0044297	cell body
0.45	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0036477	somatodendritic compartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

tr|J9PB91|J9PB91_CANLF
Uncharacterized protein
Search

0.10	Transcription factor SOX-4 (Fragment)

0.55	GO:0072395	signal transduction involved in cell cycle checkpoint
0.54	GO:0003357	noradrenergic neuron differentiation
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0014009	glial cell proliferation
0.54	GO:0003211	cardiac ventricle formation
0.54	GO:0016331	morphogenesis of embryonic epithelium
0.54	GO:0060174	limb bud formation
0.54	GO:0021510	spinal cord development
0.53	GO:0048485	sympathetic nervous system development
0.53	GO:0006366	transcription by RNA polymerase II

0.58	GO:0140110	transcription regulator activity
0.54	GO:0001046	core promoter sequence-specific DNA binding
0.50	GO:0001158	enhancer sequence-specific DNA binding
0.47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.44	GO:0008135	translation factor activity, RNA binding
0.41	GO:0046982	protein heterodimerization activity

0.60	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.41	GO:0005667	transcription factor complex
0.39	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.38	GO:0032993	protein-DNA complex

tr|J9PB92|J9PB92_CANLF
Uncharacterized protein
Search

CARD8

0.93	Caspase recruitment domain-containing protein 8

0.74	GO:0042981	regulation of apoptotic process
0.56	GO:0050713	negative regulation of interleukin-1 beta secretion
0.56	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.56	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.55	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.55	GO:0050718	positive regulation of interleukin-1 beta secretion
0.54	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.53	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.51	GO:0043068	positive regulation of programmed cell death

0.59	GO:0032089	NACHT domain binding
0.56	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.56	GO:0050700	CARD domain binding
0.49	GO:0042803	protein homodimerization activity

0.59	GO:0072559	NLRP3 inflammasome complex
0.47	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|J9PB97|J9PB97_CANLF
Uncharacterized protein
Search

NMRAL1

0.86	NmrA like redox sensor 1

0.43

GO:0000050

urea cycle

0.73

GO:0042802

identical protein binding

0.61	GO:0005634	nucleus
0.47	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005829	cytosol

tr|J9PB98|J9PB98_CANLF
Uncharacterized protein
Search

CLIC3

0.79	Chloride intracellular channel a

0.76	GO:1902476	chloride transmembrane transport
0.70	GO:0034765	regulation of ion transmembrane transport
0.55	GO:0051284	positive regulation of sequestering of calcium ion
0.54	GO:0050849	negative regulation of calcium-mediated signaling
0.54	GO:0010523	negative regulation of calcium ion transport into cytosol
0.53	GO:0032410	negative regulation of transporter activity
0.53	GO:0034763	negative regulation of transmembrane transport
0.51	GO:0022898	regulation of transmembrane transporter activity
0.48	GO:0006749	glutathione metabolic process
0.46	GO:0060088	auditory receptor cell stereocilium organization

0.77	GO:0005254	chloride channel activity
0.66	GO:0022832	voltage-gated channel activity
0.64	GO:0022839	ion gated channel activity
0.64	GO:0008381	mechanosensitive ion channel activity
0.49	GO:0004364	glutathione transferase activity
0.43	GO:0004602	glutathione peroxidase activity
0.35	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.34	GO:0005515	protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding

0.72	GO:0034707	chloride channel complex
0.49	GO:0016604	nuclear body
0.46	GO:0005737	cytoplasm
0.43	GO:0032420	stereocilium
0.42	GO:0015629	actin cytoskeleton
0.37	GO:0070062	extracellular exosome
0.36	GO:0005815	microtubule organizing center
0.35	GO:0012505	endomembrane system
0.33	GO:0097708	intracellular vesicle
0.32	GO:0071944	cell periphery

0.49

EC:2.5.1.18

GO:0004364

tr|J9PBA0|J9PBA0_CANLF
Uncharacterized protein
Search

C1QTNF5

0.95	Adiponectin 2

0.58	GO:0070206	protein trimerization
0.58	GO:0048839	inner ear development
0.51	GO:0009306	protein secretion
0.38	GO:0009405	pathogenesis
0.34	GO:0050673	epithelial cell proliferation
0.34	GO:0048593	camera-type eye morphogenesis
0.33	GO:0007160	cell-matrix adhesion

0.53	GO:0042802	identical protein binding
0.34	GO:0005201	extracellular matrix structural constituent
0.33	GO:0008201	heparin binding
0.31	GO:0046872	metal ion binding

0.74	GO:0005581	collagen trimer
0.64	GO:0005576	extracellular region
0.60	GO:0016328	lateral plasma membrane
0.58	GO:0016324	apical plasma membrane
0.57	GO:0005923	bicellular tight junction
0.55	GO:0030133	transport vesicle
0.50	GO:0042995	cell projection
0.37	GO:0019867	outer membrane
0.32	GO:0099512	supramolecular fiber
0.30	GO:0016021	integral component of membrane

tr|J9PBA1|J9PBA1_CANLF
Autophagy-related protein 3
Search

ATG3

0.74	Autophagy-related protein 3

0.76	GO:0006914	autophagy
0.64	GO:0015031	protein transport
0.57	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.56	GO:0050765	negative regulation of phagocytosis
0.55	GO:1902017	regulation of cilium assembly
0.54	GO:0007033	vacuole organization
0.50	GO:0070925	organelle assembly
0.49	GO:0016567	protein ubiquitination
0.46	GO:0061726	mitochondrion disassembly
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0019776	Atg8 ligase activity
0.58	GO:0019777	Atg12 transferase activity
0.48	GO:0019899	enzyme binding
0.32	GO:0005507	copper ion binding
0.32	GO:0016491	oxidoreductase activity

0.57	GO:0000153	cytoplasmic ubiquitin ligase complex
0.49	GO:0005829	cytosol

0.32

GO:0016491

tr|J9PBA3|J9PBA3_CANLF
Uncharacterized protein
Search

GAPDH

0.53	Glyceraldehyde-3-phosphate dehydrogenase

0.65	GO:0006006	glucose metabolic process
0.65	GO:0006757	ATP generation from ADP
0.63	GO:0006090	pyruvate metabolic process
0.62	GO:0016052	carbohydrate catabolic process
0.62	GO:0019362	pyridine nucleotide metabolic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.48	GO:0051402	neuron apoptotic process
0.46	GO:0051873	killing by host of symbiont cells
0.46	GO:0050821	protein stabilization

0.76	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.64	GO:0050661	NADP binding
0.63	GO:0051287	NAD binding
0.51	GO:0035605	peptidyl-cysteine S-nitrosylase activity
0.47	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.46	GO:0097718	disordered domain specific binding
0.44	GO:0008017	microtubule binding
0.42	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding

0.53	GO:0097452	GAIT complex
0.45	GO:0005829	cytosol
0.44	GO:0005811	lipid droplet
0.43	GO:0031965	nuclear membrane
0.43	GO:0015630	microtubule cytoskeleton
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome

0.76

EC:1.2.1.12

GO:0004365

tr|J9PBA5|J9PBA5_CANLF
Uncharacterized protein
Search

0.54	GO:0006413	translational initiation
0.50	GO:0045596	negative regulation of cell differentiation
0.50	GO:0045112	integrin biosynthetic process
0.50	GO:0002009	morphogenesis of an epithelium
0.49	GO:0051241	negative regulation of multicellular organismal process
0.49	GO:0009887	animal organ morphogenesis
0.49	GO:0035989	tendon development
0.49	GO:0032964	collagen biosynthetic process
0.48	GO:2000026	regulation of multicellular organismal development
0.47	GO:0030199	collagen fibril organization

0.54	GO:0003743	translation initiation factor activity
0.49	GO:0003924	GTPase activity
0.48	GO:0048407	platelet-derived growth factor binding
0.48	GO:0005525	GTP binding
0.47	GO:0043394	proteoglycan binding
0.46	GO:0008201	heparin binding
0.46	GO:0005201	extracellular matrix structural constituent
0.46	GO:0042302	structural constituent of cuticle
0.42	GO:0003887	DNA-directed DNA polymerase activity
0.40	GO:0003677	DNA binding

0.49	GO:0005588	collagen type V trimer
0.47	GO:0035060	brahma complex
0.46	GO:0005604	basement membrane
0.43	GO:0005615	extracellular space
0.43	GO:0009360	DNA polymerase III complex
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.42

EC:2.7.7.7

GO:0003887

tr|J9PBA7|J9PBA7_CANLF
Uncharacterized protein
Search

PKDREJ

0.95	Polycystic kidney disease and receptor for egg jelly-related protein isoform A

0.54	GO:0050982	detection of mechanical stimulus
0.50	GO:0070588	calcium ion transmembrane transport
0.40	GO:0007340	acrosome reaction
0.40	GO:0060046	regulation of acrosome reaction
0.34	GO:0098869	cellular oxidant detoxification
0.33	GO:0001822	kidney development
0.33	GO:0055114	oxidation-reduction process

0.65	GO:0005509	calcium ion binding
0.51	GO:0005262	calcium channel activity
0.35	GO:0004096	catalase activity
0.34	GO:0020037	heme binding

0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:1.11.1.6

GO:0004096

tr|J9PBA9|J9PBA9_CANLF
Peptidylprolyl isomerase
Search

FKBP3

0.55	Peptidyl-prolyl cis-trans isomerase FKBP3

0.68	GO:0061077	chaperone-mediated protein folding
0.68	GO:0000413	protein peptidyl-prolyl isomerization

0.73	GO:0005528	FK506 binding
0.68	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.51	GO:0005515	protein binding
0.46	GO:0004872	receptor activity
0.43	GO:0003723	RNA binding

0.58	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.68

EC:5.2.1.8

GO:0003755

tr|J9PBB0|J9PBB0_CANLF
Uncharacterized protein
Search

0.77	Membrane-spanning 4-domains subfamily A member 10

0.39

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|J9PBB2|J9PBB2_CANLF
Uncharacterized protein
Search

0.94	Immunoglobulin kappa variable 2-30

0.72	GO:0002250	adaptive immune response
0.70	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.69	GO:0038095	Fc-epsilon receptor signaling pathway
0.68	GO:0002377	immunoglobulin production
0.67	GO:0030449	regulation of complement activation
0.65	GO:0002449	lymphocyte mediated immunity
0.65	GO:0006956	complement activation
0.64	GO:0050900	leukocyte migration
0.57	GO:0006898	receptor-mediated endocytosis
0.50	GO:0006508	proteolysis

0.79	GO:0003823	antigen binding
0.55	GO:0004252	serine-type endopeptidase activity
0.36	GO:0046872	metal ion binding

0.65	GO:0005615	extracellular space
0.53	GO:1903561	extracellular vesicle
0.50	GO:0005886	plasma membrane

0.55

GO:0004252

tr|J9PBB4|J9PBB4_CANLF
Uncharacterized protein
Search

0.36	GO:0006468	protein phosphorylation
0.35	GO:0035372	protein localization to microtubule
0.35	GO:0031134	sister chromatid biorientation
0.35	GO:0051315	attachment of mitotic spindle microtubules to kinetochore
0.35	GO:0034501	protein localization to kinetochore
0.35	GO:0006182	cGMP biosynthetic process
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0005975	carbohydrate metabolic process

0.36	GO:0004672	protein kinase activity
0.35	GO:0004383	guanylate cyclase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003779	actin binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0003676	nucleic acid binding

0.35	GO:0090543	Flemming body
0.34	GO:0000777	condensed chromosome kinetochore
0.34	GO:0005819	spindle
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.35

EC:4.6.1.2

GO:0004383

tr|J9PBB5|J9PBB5_CANLF
Uncharacterized protein
Search

tr|J9PBB6|J9PBB6_CANLF
Uncharacterized protein
Search

tr|J9PBB8|J9PBB8_CANLF
Uncharacterized protein
Search

PCSK5

0.74	Proprotein convertase subtilisin kexin type 5 variant 3

0.61	GO:0006508	proteolysis
0.55	GO:0002001	renin secretion into blood stream
0.53	GO:0042089	cytokine biosynthetic process
0.52	GO:0048566	embryonic digestive tract development
0.52	GO:0060976	coronary vasculature development
0.51	GO:0003279	cardiac septum development
0.50	GO:0007566	embryo implantation
0.50	GO:0048706	embryonic skeletal system development
0.50	GO:0035108	limb morphogenesis
0.50	GO:0007368	determination of left/right symmetry

0.69	GO:0004252	serine-type endopeptidase activity
0.48	GO:0042277	peptide binding
0.33	GO:0048406	nerve growth factor binding
0.33	GO:0008201	heparin binding

0.49	GO:0030141	secretory granule
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005615	extracellular space
0.32	GO:0009986	cell surface
0.32	GO:0031012	extracellular matrix
0.32	GO:1990635	proximal dendrite
0.32	GO:0043233	organelle lumen
0.32	GO:0043204	perikaryon
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005783	endoplasmic reticulum

0.69

GO:0004252

tr|J9PBB9|J9PBB9_CANLF
Elongation of very long chain fatty acids protein 4
Search

ELOVL4

0.55	Elongation of very long chain fatty acids protein 4

0.75	GO:0019367	fatty acid elongation, saturated fatty acid
0.74	GO:0042761	very long-chain fatty acid biosynthetic process
0.73	GO:0034626	fatty acid elongation, polyunsaturated fatty acid
0.72	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.69	GO:0006636	unsaturated fatty acid biosynthetic process
0.50	GO:0034625	fatty acid elongation, monounsaturated fatty acid
0.48	GO:0030148	sphingolipid biosynthetic process
0.35	GO:0009584	detection of visible light

0.81	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.81	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.81	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.81	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.73	GO:0009922	fatty acid elongase activity
0.35	GO:0008020	G-protein coupled photoreceptor activity
0.33	GO:0005515	protein binding

0.62	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.81

EC:2.3.1.199

GO:0102338

tr|J9PBC0|J9PBC0_CANLF
Uncharacterized protein
Search

MSANTD4

0.69	Myb/SANT DNA binding domain containing 4 with coiled-coils

0.50

GO:0003677

DNA binding

0.49

GO:0005634

nucleus

tr|J9PBC1|J9PBC1_CANLF
Uncharacterized protein
Search

0.79	probable G-protein coupled receptor 141

0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0009755	hormone-mediated signaling pathway
0.40	GO:0032467	positive regulation of cytokinesis
0.39	GO:0050796	regulation of insulin secretion
0.38	GO:0042593	glucose homeostasis
0.37	GO:0071385	cellular response to glucocorticoid stimulus
0.36	GO:0008285	negative regulation of cell proliferation
0.36	GO:0007268	chemical synaptic transmission
0.34	GO:0045454	cell redox homeostasis

0.69	GO:0004930	G-protein coupled receptor activity
0.54	GO:0001653	peptide receptor activity
0.37	GO:0042923	neuropeptide binding
0.33	GO:0005515	protein binding

0.36	GO:0043005	neuron projection
0.35	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|J9PBC5|J9PBC5_CANLF
40S ribosomal protein S3a
Search

tr|J9PBC6|J9PBC6_CANLF
Uncharacterized protein
Search

INO80B

0.97	LOW QUALITY PROTEIN: INO80 complex subunit B

0.77	GO:0006338	chromatin remodeling
0.36	GO:0006310	DNA recombination
0.36	GO:0006281	DNA repair
0.35	GO:0016579	protein deubiquitination
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0006355	regulation of transcription, DNA-templated

0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.32	GO:0016874	ligase activity

0.79	GO:0031011	Ino80 complex
0.37	GO:0005730	nucleolus
0.35	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016874

tr|J9PBC8|J9PBC8_CANLF
Uncharacterized protein
Search

TAZ

0.76	Tafazzin (Predicted)

0.67	GO:0006644	phospholipid metabolic process
0.58	GO:0007507	heart development
0.57	GO:0007007	inner mitochondrial membrane organization
0.56	GO:0060048	cardiac muscle contraction
0.56	GO:0032981	mitochondrial respiratory chain complex I assembly
0.55	GO:0007519	skeletal muscle tissue development
0.53	GO:0030097	hemopoiesis
0.51	GO:0046486	glycerolipid metabolic process
0.50	GO:0042775	mitochondrial ATP synthesis coupled electron transport
0.46	GO:0008610	lipid biosynthetic process

0.63

GO:0016746

transferase activity, transferring acyl groups

0.48	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.45	GO:0005634	nucleus
0.40	GO:0031967	organelle envelope
0.40	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.63

EC:2.3

GO:0016746

tr|J9PBC9|J9PBC9_CANLF
Uncharacterized protein
Search

ATP5J2

0.91	mitochondrial ATP synthase subunit F

0.42	GO:0006754	ATP biosynthetic process
0.40	GO:0015992	proton transport
0.37	GO:0042407	cristae formation
0.36	GO:0006839	mitochondrial transport
0.35	GO:0046907	intracellular transport
0.34	GO:0098662	inorganic cation transmembrane transport
0.33	GO:0006355	regulation of transcription, DNA-templated

0.43	GO:0016887	ATPase activity
0.34	GO:0022857	transmembrane transporter activity
0.33	GO:0003676	nucleic acid binding

0.51	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.43	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.39	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.43

GO:0016887

tr|J9PBD0|J9PBD0_CANLF
Uncharacterized protein
Search

XAF1

0.87	XIAP associated factor 1

0.78	GO:0006915	apoptotic process
0.62	GO:0034097	response to cytokine

0.49

GO:0008270

zinc ion binding

0.46	GO:0005634	nucleus
0.46	GO:0005739	mitochondrion

tr|J9PBD1|J9PBD1_CANLF
Uncharacterized protein
Search

0.10	Nuclear envelope pore membrane protein POM 121

0.62	GO:0006606	protein import into nucleus
0.59	GO:0051028	mRNA transport
0.58	GO:0006405	RNA export from nucleus
0.57	GO:0007077	mitotic nuclear envelope disassembly
0.55	GO:1900034	regulation of cellular response to heat
0.54	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.54	GO:0006110	regulation of glycolytic process
0.54	GO:0051031	tRNA transport
0.53	GO:0060964	regulation of gene silencing by miRNA
0.51	GO:0016925	protein sumoylation

0.65	GO:0008139	nuclear localization sequence binding
0.61	GO:0017056	structural constituent of nuclear pore
0.46	GO:0005515	protein binding
0.42	GO:0035091	phosphatidylinositol binding

0.67	GO:0044613	nuclear pore central transport channel
0.66	GO:0044615	nuclear pore nuclear basket
0.65	GO:0031965	nuclear membrane
0.54	GO:0005789	endoplasmic reticulum membrane
0.53	GO:0005654	nucleoplasm
0.44	GO:0044216	other organism cell
0.44	GO:0018995	host
0.43	GO:0030136	clathrin-coated vesicle
0.30	GO:0016021	integral component of membrane

tr|J9PBD2|J9PBD2_CANLF
Uncharacterized protein
Search

LOC257642

0.77	rRNA promoter binding protein

0.85	GO:0009303	rRNA transcription
0.80	GO:0008283	cell proliferation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.73	GO:0008134	transcription factor binding
0.72	GO:0003690	double-stranded DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

tr|J9PBD3|J9PBD3_CANLF
Uncharacterized protein
Search

RPL10

0.42	Ribosomal protein 10

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.51	GO:1990403	embryonic brain development
0.49	GO:0000027	ribosomal large subunit assembly
0.48	GO:0007283	spermatogenesis
0.45	GO:0006417	regulation of translation
0.42	GO:0007420	brain development
0.38	GO:0043066	negative regulation of apoptotic process

0.64	GO:0003735	structural constituent of ribosome
0.48	GO:0045182	translation regulator activity
0.41	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0005092	GDP-dissociation inhibitor activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.51	GO:0044445	cytosolic part
0.50	GO:0005783	endoplasmic reticulum
0.47	GO:0005844	polysome
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

tr|J9PBD4|J9PBD4_CANLF
Uncharacterized protein
Search

IGLON5

0.92	Opioid binding protein/cell adhesion molecule like

0.51	GO:0035641	locomotory exploration behavior
0.47	GO:0007155	cell adhesion
0.40	GO:0006501	C-terminal protein lipidation
0.40	GO:0008038	neuron recognition
0.37	GO:0032355	response to estradiol
0.37	GO:0021549	cerebellum development
0.37	GO:0010977	negative regulation of neuron projection development

0.42	GO:0005515	protein binding
0.35	GO:0030246	carbohydrate binding

0.50	GO:0031225	anchored component of membrane
0.44	GO:0005829	cytosol
0.42	GO:0005576	extracellular region
0.41	GO:0005886	plasma membrane
0.37	GO:0031982	vesicle
0.37	GO:0060076	excitatory synapse
0.36	GO:0030424	axon
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

tr|J9PBD5|J9PBD5_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.56	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBD6|J9PBD6_CANLF
Uncharacterized protein
Search

0.75	regulator of cell cycle RGCC

0.73	GO:0051726	regulation of cell cycle
0.68	GO:0072537	fibroblast activation
0.67	GO:0003331	positive regulation of extracellular matrix constituent secretion
0.67	GO:0090272	negative regulation of fibroblast growth factor production
0.67	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin
0.66	GO:1901203	positive regulation of extracellular matrix assembly
0.65	GO:2000353	positive regulation of endothelial cell apoptotic process
0.64	GO:0032967	positive regulation of collagen biosynthetic process
0.64	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.63	GO:0001937	negative regulation of endothelial cell proliferation

0.64	GO:0070412	R-SMAD binding
0.63	GO:0030295	protein kinase activator activity
0.60	GO:0019901	protein kinase binding
0.34	GO:0005507	copper ion binding
0.34	GO:0003735	structural constituent of ribosome

0.58	GO:0005813	centrosome
0.55	GO:0005730	nucleolus
0.42	GO:0005737	cytoplasm
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|J9PBD8|J9PBD8_CANLF
Uncharacterized protein
Search

TNXB

0.60	Tenascin XB

0.85	GO:0030199	collagen fibril organization
0.58	GO:0043506	regulation of JUN kinase activity
0.56	GO:0007160	cell-matrix adhesion
0.56	GO:0006641	triglyceride metabolic process
0.54	GO:0098609	cell-cell adhesion
0.50	GO:0048251	elastic fiber assembly
0.50	GO:0006631	fatty acid metabolic process
0.49	GO:0032963	collagen metabolic process
0.42	GO:0030036	actin cytoskeleton organization
0.39	GO:0045785	positive regulation of cell adhesion

0.60	GO:0008201	heparin binding
0.57	GO:0005518	collagen binding
0.45	GO:0005178	integrin binding
0.36	GO:0019838	growth factor binding
0.35	GO:0045545	syndecan binding
0.34	GO:0090729	toxin activity
0.32	GO:0005201	extracellular matrix structural constituent

0.74	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0005615	extracellular space
0.48	GO:0044420	extracellular matrix component
0.47	GO:0005581	collagen trimer
0.44	GO:0099512	supramolecular fiber
0.38	GO:1903561	extracellular vesicle
0.35	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|J9PBD9|J9PBD9_CANLF
Uncharacterized protein
Search

0.34	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse
0.33	GO:1903955	positive regulation of protein targeting to mitochondrion
0.33	GO:0007018	microtubule-based movement
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0006646	phosphatidylethanolamine biosynthetic process
0.33	GO:0006420	arginyl-tRNA aminoacylation
0.32	GO:0050790	regulation of catalytic activity
0.32	GO:0055085	transmembrane transport

0.33	GO:0004307	ethanolaminephosphotransferase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0004814	arginine-tRNA ligase activity
0.33	GO:0030234	enzyme regulator activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:1905369	endopeptidase complex
0.32	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:2.7.8.1

GO:0004307

tr|J9PBE0|J9PBE0_CANLF
Uncharacterized protein
Search

UQCRB

0.74	Cytochrome b-c1 complex subunit 7

0.72	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.46	GO:0017062	respiratory chain complex III assembly
0.46	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.45	GO:0033108	mitochondrial respiratory chain complex assembly
0.40	GO:0009060	aerobic respiration
0.39	GO:0001525	angiogenesis
0.37	GO:0007406	negative regulation of neuroblast proliferation
0.35	GO:0051291	protein heterooligomerization
0.34	GO:0008340	determination of adult lifespan
0.34	GO:0000302	response to reactive oxygen species

0.43	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.39	GO:0009055	electron transfer activity
0.34	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.81

GO:0005750

mitochondrial respiratory chain complex III

0.43

EC:1.10.2

GO:0016681

tr|J9PBE1|J9PBE1_CANLF
Uncharacterized protein
Search

HNRNPA1

0.76	Heterogeneous nuclear ribonucleoprotein A1

0.52	GO:1903936	cellular response to sodium arsenite
0.50	GO:0032211	negative regulation of telomere maintenance via telomerase
0.49	GO:0032212	positive regulation of telomere maintenance via telomerase
0.49	GO:0042149	cellular response to glucose starvation
0.49	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.47	GO:0051168	nuclear export
0.45	GO:0051170	nuclear import
0.43	GO:0033036	macromolecule localization
0.42	GO:0071705	nitrogen compound transport
0.42	GO:0071702	organic substance transport

0.59	GO:0003723	RNA binding
0.51	GO:0098505	G-rich strand telomeric DNA binding
0.46	GO:0019904	protein domain specific binding
0.38	GO:0042802	identical protein binding
0.36	GO:0036310	annealing helicase activity
0.34	GO:0008134	transcription factor binding

0.65	GO:0019013	viral nucleocapsid
0.57	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0005654	nucleoplasm
0.42	GO:0030117	membrane coat
0.41	GO:1902494	catalytic complex
0.40	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBE3|J9PBE3_CANLF
Uncharacterized protein
Search

tr|J9PBE4|J9PBE4_CANLF
Uncharacterized protein
Search

0.10	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3-like protein (Fragment)

0.76	GO:0043547	positive regulation of GTPase activity
0.73	GO:0016477	cell migration
0.58	GO:0051492	regulation of stress fiber assembly
0.44	GO:1903527	positive regulation of membrane tubulation
0.43	GO:0061000	negative regulation of dendritic spine development
0.43	GO:0071803	positive regulation of podosome assembly
0.41	GO:0060271	cilium assembly
0.33	GO:0006351	transcription, DNA-templated

0.76	GO:0005096	GTPase activator activity
0.52	GO:0046872	metal ion binding
0.42	GO:0001786	phosphatidylserine binding
0.42	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.42	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.41	GO:0045296	cadherin binding

0.76	GO:0005925	focal adhesion
0.57	GO:0001726	ruffle
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.42	GO:0002102	podosome
0.42	GO:0043197	dendritic spine
0.41	GO:0031253	cell projection membrane

tr|J9PBE5|J9PBE5_CANLF
Uncharacterized protein
Search

0.62	Sesquipedalian-1

0.81	GO:0001881	receptor recycling
0.78	GO:0007032	endosome organization
0.74	GO:0042147	retrograde transport, endosome to Golgi
0.46	GO:0006465	signal peptide processing
0.42	GO:0032101	regulation of response to external stimulus
0.42	GO:1905303	positive regulation of macropinocytosis
0.41	GO:0044351	macropinocytosis
0.41	GO:0043327	chemotaxis to cAMP
0.41	GO:0050765	negative regulation of phagocytosis
0.41	GO:0043085	positive regulation of catalytic activity

0.42	GO:0017171	serine hydrolase activity
0.42	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity
0.41	GO:0004691	cAMP-dependent protein kinase activity
0.41	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.40	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.39	GO:0004049	anthranilate synthase activity
0.38	GO:0005096	GTPase activator activity
0.38	GO:0051015	actin filament binding
0.38	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding

0.76	GO:0055037	recycling endosome
0.74	GO:0005769	early endosome
0.73	GO:0005802	trans-Golgi network
0.64	GO:0005829	cytosol
0.47	GO:0005787	signal peptidase complex
0.41	GO:0005950	anthranilate synthase complex
0.39	GO:0005938	cell cortex
0.38	GO:0016459	myosin complex
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.42

EC:3.1.3.66

GO:0016316

tr|J9PBE9|J9PBE9_CANLF
Uncharacterized protein
Search

GPN1

0.79	GPN-loop GTPase 1

0.52	GO:1990022	RNA polymerase III complex localization to nucleus
0.52	GO:0044376	RNA polymerase II complex import to nucleus

0.68	GO:0003924	GTPase activity
0.35	GO:0001883	purine nucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.35	GO:0032549	ribonucleoside binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032555	purine ribonucleotide binding
0.33	GO:0005515	protein binding

0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|J9PBF0|J9PBF0_CANLF
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
Search

POMGNT2

0.97	Glycosyltransferase-like domain-containing protein 2

0.58	GO:0035269	protein O-linked mannosylation
0.57	GO:0001764	neuron migration
0.35	GO:0048747	muscle fiber development
0.35	GO:0060041	retina development in camera-type eye
0.34	GO:0007420	brain development

0.61	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0005515	protein binding

0.51	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016757

tr|J9PBF1|J9PBF1_CANLF
Uncharacterized protein
Search

ODF1

0.96	LOW QUALITY PROTEIN: outer dense fiber protein 1

0.47	GO:0007283	spermatogenesis
0.44	GO:0030154	cell differentiation
0.43	GO:0007275	multicellular organism development

0.40

GO:0019904

protein domain specific binding

0.87	GO:0001520	outer dense fiber
0.37	GO:0005634	nucleus

tr|J9PBF2|J9PBF2_CANLF
Uncharacterized protein
Search

0.55	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.70	GO:0010469	regulation of receptor activity
0.50	GO:0071674	mononuclear cell migration
0.50	GO:0072676	lymphocyte migration
0.49	GO:1990266	neutrophil migration
0.49	GO:0071347	cellular response to interleukin-1
0.48	GO:0071356	cellular response to tumor necrosis factor
0.48	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.48	GO:0070098	chemokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.50	GO:0048020	CCR chemokine receptor binding

0.68

GO:0005615

extracellular space

tr|J9PBF3|J9PBF3_CANLF
Uncharacterized protein
Search

GPR61

0.95	G protein-coupled receptor 61

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.58	GO:0043950	positive regulation of cAMP-mediated signaling

0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.53	GO:0043235	receptor complex
0.42	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|J9PBF4|J9PBF4_CANLF
Uncharacterized protein
Search

RPL23A

0.83	Ribosomal protein L23A, pseudogene 3

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0000027	ribosomal large subunit assembly
0.41	GO:0008283	cell proliferation
0.39	GO:0031016	pancreas development
0.37	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0007250	activation of NF-kappaB-inducing kinase activity

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0003723	RNA binding
0.41	GO:0045296	cadherin binding
0.32	GO:0005216	ion channel activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.42	GO:0031932	TORC2 complex
0.38	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBF5|J9PBF5_CANLF
Uncharacterized protein
Search

PASD1

0.81	PAS domain containing repressor 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0042754	negative regulation of circadian rhythm
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.49	GO:1902679	negative regulation of RNA biosynthetic process

0.63	GO:0046983	protein dimerization activity
0.57	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001223	transcription coactivator binding
0.51	GO:0003677	DNA binding

0.69	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.53	GO:0017053	transcriptional repressor complex
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005737	cytoplasm
0.42	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBF7|J9PBF7_CANLF
Uncharacterized protein
Search

tr|J9PBF8|J9PBF8_CANLF
Uncharacterized protein
Search

VGLL3

0.96	Cilia and flagella-associated protein 70

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0007519	skeletal muscle tissue development
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0048703	embryonic viscerocranium morphogenesis
0.34	GO:0014032	neural crest cell development

0.53	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0008022	protein C-terminus binding
0.41	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|J9PBG0|J9PBG0_CANLF
Uncharacterized protein
Search

0.86	BUD31 homolog (S. cerevisiae)

0.48	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:2000825	positive regulation of androgen receptor activity

0.43	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.43	GO:0035257	nuclear hormone receptor binding

0.61	GO:0005634	nucleus
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0044446	intracellular organelle part
0.39	GO:0005694	chromosome
0.39	GO:0031974	membrane-enclosed lumen
0.35	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBG1|J9PBG1_CANLF
Uncharacterized protein
Search

ZBTB5

0.97	Zinc finger and BTB domain-containing protein 5

0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.60	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.48	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:2.7.7.6

GO:0003899

tr|J9PBG2|J9PBG2_CANLF
Uncharacterized protein
Search

YBX2

0.95	Y-box binding protein 2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0048477	oogenesis
0.41	GO:0007283	spermatogenesis
0.39	GO:0034248	regulation of cellular amide metabolic process
0.39	GO:1902369	negative regulation of RNA catabolic process
0.39	GO:0051100	negative regulation of binding
0.39	GO:0032268	regulation of cellular protein metabolic process
0.37	GO:1903312	negative regulation of mRNA metabolic process

0.54	GO:0003677	DNA binding
0.39	GO:0003730	mRNA 3'-UTR binding
0.38	GO:0045182	translation regulator activity
0.38	GO:0003682	chromatin binding
0.37	GO:0043021	ribonucleoprotein complex binding
0.37	GO:0008289	lipid binding

0.67	GO:0001650	fibrillar center
0.38	GO:0005844	polysome
0.34	GO:0005737	cytoplasm

tr|J9PBG4|J9PBG4_CANLF
PAB-dependent poly(A)-specific ribonuclease subunit PAN3
Search

PAN3

0.56	Putative polya ribonuclease subunit (Fragment)

0.84	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.70	GO:0006397	mRNA processing
0.63	GO:0006468	protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.59	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0046872	metal ion binding

0.85	GO:0031251	PAN complex
0.30	GO:0016020	membrane

tr|J9PBG5|J9PBG5_CANLF
Uncharacterized protein
Search

0.36	GO:0031047	gene silencing by RNA
0.36	GO:0006367	transcription initiation from RNA polymerase II promoter
0.35	GO:0001522	pseudouridine synthesis
0.33	GO:0019538	protein metabolic process

0.58	GO:0016874	ligase activity
0.52	GO:0046872	metal ion binding
0.37	GO:0003682	chromatin binding
0.36	GO:0031177	phosphopantetheine binding
0.35	GO:0005515	protein binding
0.35	GO:0009982	pseudouridine synthase activity
0.35	GO:0003723	RNA binding

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.58

GO:0016874

tr|J9PBG6|J9PBG6_CANLF
Uncharacterized protein
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBG9|J9PBG9_CANLF
Uncharacterized protein
Search

tr|J9PBH1|J9PBH1_CANLF
Uncharacterized protein
Search

POGZ

0.97	Pogo transposable element derived with ZNF domain

0.58	GO:0051382	kinetochore assembly
0.57	GO:0007064	mitotic sister chromatid cohesion
0.36	GO:0051301	cell division

0.53	GO:0003677	DNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.54	GO:0000790	nuclear chromatin
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBH2|J9PBH2_CANLF
Uncharacterized protein
Search

0.45	GO:0006334	nucleosome assembly
0.41	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.41	GO:0006487	protein N-linked glycosylation
0.40	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0042125	protein galactosylation
0.38	GO:0009272	fungal-type cell wall biogenesis
0.38	GO:0019673	GDP-mannose metabolic process
0.38	GO:0006355	regulation of transcription, DNA-templated
0.37	GO:0006260	DNA replication
0.37	GO:0006281	DNA repair

0.60	GO:0000062	fatty-acyl-CoA binding
0.50	GO:0008270	zinc ion binding
0.45	GO:0003676	nucleic acid binding
0.43	GO:0003779	actin binding
0.41	GO:0004984	olfactory receptor activity
0.40	GO:0005198	structural molecule activity
0.40	GO:0031278	alpha-1,2-galactosyltransferase activity
0.40	GO:0004930	G-protein coupled receptor activity
0.39	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
0.38	GO:0008446	GDP-mannose 4,6-dehydratase activity

0.43	GO:0043229	intracellular organelle
0.43	GO:0043228	non-membrane-bounded organelle
0.43	GO:0033186	CAF-1 complex
0.41	GO:0043227	membrane-bounded organelle
0.40	GO:0044815	DNA packaging complex
0.40	GO:0032993	protein-DNA complex
0.39	GO:0009986	cell surface
0.38	GO:0044422	organelle part
0.37	GO:0044444	cytoplasmic part
0.36	GO:0012505	endomembrane system

0.40	EC:2.4.1	GO:0031278
0.38	KEGG:R00888	GO:0008446

tr|J9PBH7|J9PBH7_CANLF
Uncharacterized protein
Search

MFSD3

0.35	LOW QUALITY PROTEIN: major facilitator superfamily domain-containing protein 3

0.55	GO:0015876	acetyl-CoA transport
0.52	GO:0055085	transmembrane transport
0.43	GO:0015992	proton transport

0.55	GO:0008521	acetyl-CoA transmembrane transporter activity
0.49	GO:0015295	solute:proton symporter activity

0.45

GO:0005887

integral component of plasma membrane

tr|J9PBH8|J9PBH8_CANLF
Uncharacterized protein
Search

APOL3

0.73	Apolipoprotein L3

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.44	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.43	GO:0006954	inflammatory response
0.38	GO:0007165	signal transduction
0.33	GO:0055114	oxidation-reduction process

0.72	GO:0008289	lipid binding
0.42	GO:0005319	lipid transporter activity
0.39	GO:0004871	signal transducer activity
0.35	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.34	GO:0016853	isomerase activity

0.66	GO:0005576	extracellular region
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:1.3

GO:0016627

tr|J9PBI0|J9PBI0_CANLF
Uncharacterized protein
Search

RNF125

0.47	E3 ubiquitin-protein ligase

0.70	GO:0039536	negative regulation of RIG-I signaling pathway
0.68	GO:0032480	negative regulation of type I interferon production
0.64	GO:0000209	protein polyubiquitination
0.63	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.53	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:1990830	cellular response to leukemia inhibitory factor
0.44	GO:0006955	immune response
0.43	GO:0046597	negative regulation of viral entry into host cell
0.42	GO:1902187	negative regulation of viral release from host cell
0.41	GO:0051091	positive regulation of DNA binding transcription factor activity

0.67	GO:0031624	ubiquitin conjugating enzyme binding
0.65	GO:0002039	p53 binding
0.61	GO:0061630	ubiquitin protein ligase activity
0.54	GO:0008270	zinc ion binding
0.51	GO:0016874	ligase activity
0.35	GO:0001784	phosphotyrosine residue binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0004519	endonuclease activity

0.68	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.59	GO:0000139	Golgi membrane
0.36	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.51

GO:0016874

tr|J9PBI5|J9PBI5_CANLF
Uncharacterized protein
Search

0.10	Zinc finger protein 25 (Fragment)

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0022900	electron transport chain
0.32	GO:0044267	cellular protein metabolic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.39	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity

0.44	GO:0005622	intracellular
0.42	GO:0043233	organelle lumen
0.41	GO:0043227	membrane-bounded organelle
0.34	GO:0012505	endomembrane system
0.34	GO:0031975	envelope
0.33	GO:0070469	respiratory chain
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.9

GO:0016675

tr|J9PBI6|J9PBI6_CANLF
Uncharacterized protein
Search

RPL31

0.69	Ribosomal protein L31

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0006298	mismatch repair
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0042254	ribosome biogenesis

0.62	GO:0003735	structural constituent of ribosome
0.35	GO:0003796	lysozyme activity
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0004519	endonuclease activity

0.60	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.47	GO:0005844	polysome
0.42	GO:0044446	intracellular organelle part
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.35	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098588	bounding membrane of organelle

0.35

GO:0003796

tr|J9PBI7|J9PBI7_CANLF
Uncharacterized protein
Search

0.88	Mitochondrial calcium uniporter regulator 1

0.85	GO:0006851	mitochondrial calcium ion transmembrane transport
0.64	GO:0051561	positive regulation of mitochondrial calcium ion concentration
0.60	GO:0070509	calcium ion import
0.56	GO:0060401	cytosolic calcium ion transport
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0005515	protein binding
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.58

GO:0031305

integral component of mitochondrial inner membrane

0.33

EC:1.1.1

GO:0016616

tr|J9PBI8|J9PBI8_CANLF
Uncharacterized protein
Search

GPR132

0.81	G protein-coupled receptor 4

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.56	GO:0000082	G1/S transition of mitotic cell cycle
0.48	GO:0009268	response to pH
0.46	GO:0072144	glomerular mesangial cell development
0.46	GO:0051239	regulation of multicellular organismal process
0.45	GO:0060055	angiogenesis involved in wound healing
0.44	GO:0051093	negative regulation of developmental process
0.43	GO:0051047	positive regulation of secretion
0.42	GO:0035590	purinergic nucleotide receptor signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.42	GO:0016502	nucleotide receptor activity
0.41	GO:0035586	purinergic receptor activity
0.32	GO:0001653	peptide receptor activity
0.32	GO:0030594	neurotransmitter receptor activity
0.32	GO:0008233	peptidase activity

0.37

GO:0005887

integral component of plasma membrane

0.32

GO:0008233

tr|J9PBI9|J9PBI9_CANLF
Uncharacterized protein
Search

0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0065009	regulation of molecular function

0.33

GO:0005085

guanyl-nucleotide exchange factor activity

0.34	GO:0035102	PRC1 complex
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBJ0|J9PBJ0_CANLF
Uncharacterized protein
Search

SMYD3

0.80	SET and MYND domain-containing protein 3

0.67	GO:0071549	cellular response to dexamethasone stimulus
0.66	GO:0034968	histone lysine methylation
0.65	GO:0014904	myotube cell development
0.64	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.61	GO:0006469	negative regulation of protein kinase activity
0.60	GO:0006334	nucleosome assembly
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0045184	establishment of protein localization
0.42	GO:0060538	skeletal muscle organ development
0.42	GO:0003007	heart morphogenesis

0.68	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
0.67	GO:0018024	histone-lysine N-methyltransferase activity
0.65	GO:0000993	RNA polymerase II core binding
0.61	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.32	GO:0015299	solute:proton antiporter activity
0.32	GO:0003723	RNA binding

0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol
0.35	GO:0034708	methyltransferase complex
0.33	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

0.67

EC:2.1.1.43

GO:0018024

tr|J9PBJ6|J9PBJ6_CANLF
Uncharacterized protein
Search

0.59	GO:0039693	viral DNA genome replication
0.47	GO:0006508	proteolysis
0.41	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.41	GO:0006754	ATP biosynthetic process
0.39	GO:0030036	actin cytoskeleton organization
0.38	GO:0071456	cellular response to hypoxia
0.38	GO:0042177	negative regulation of protein catabolic process
0.37	GO:0030838	positive regulation of actin filament polymerization
0.37	GO:0043066	negative regulation of apoptotic process
0.37	GO:0097435	supramolecular fiber organization

0.61	GO:0019784	NEDD8-specific protease activity
0.46	GO:0005199	structural constituent of cell wall
0.41	GO:0003779	actin binding
0.41	GO:0003723	RNA binding
0.39	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0046872	metal ion binding
0.37	GO:0008017	microtubule binding
0.37	GO:0017048	Rho GTPase binding
0.36	GO:0003677	DNA binding
0.35	GO:0003700	DNA binding transcription factor activity

0.60	GO:0019033	viral tegument
0.43	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.38	GO:0005884	actin filament
0.37	GO:0036338	viral membrane
0.36	GO:0005730	nucleolus
0.36	GO:0005829	cytosol

tr|J9PBJ7|J9PBJ7_CANLF
Uncharacterized protein
Search

SYT15

0.81	Synaptotagmin XV

0.58	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.57	GO:0017158	regulation of calcium ion-dependent exocytosis
0.55	GO:0006906	vesicle fusion
0.46	GO:0046580	negative regulation of Ras protein signal transduction
0.44	GO:0043087	regulation of GTPase activity
0.43	GO:0051345	positive regulation of hydrolase activity
0.40	GO:0035556	intracellular signal transduction
0.32	GO:0023014	signal transduction by protein phosphorylation

0.56	GO:0019905	syntaxin binding
0.55	GO:0005543	phospholipid binding
0.54	GO:0030276	clathrin binding
0.49	GO:0005509	calcium ion binding
0.44	GO:0005096	GTPase activator activity

0.59	GO:0019898	extrinsic component of membrane
0.54	GO:0098793	presynapse
0.43	GO:0005886	plasma membrane
0.36	GO:0098562	cytoplasmic side of membrane
0.35	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|J9PBJ8|J9PBJ8_CANLF
Uncharacterized protein
Search

BUD13

0.95	BUD13 homolog (Predicted)

0.40	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.39	GO:0051028	mRNA transport
0.39	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:0006405	RNA export from nucleus

0.37	GO:0003723	RNA binding
0.37	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.36	GO:0043234	protein complex
0.36	GO:0044446	intracellular organelle part

tr|J9PBK1|J9PBK1_CANLF
Uncharacterized protein
Search

IGSF6

0.97	Immunoglobulin superfamily member 6

0.38	GO:0006955	immune response
0.38	GO:0007166	cell surface receptor signaling pathway

0.37	GO:0099600	transmembrane receptor activity
0.37	GO:0038023	signaling receptor activity

0.37

GO:0005887

integral component of plasma membrane

tr|J9PBK2|J9PBK2_CANLF
Uncharacterized protein
Search

0.11	Microtubule-associated serine/threonine-protein kinase 4 (Fragment)

0.61	GO:0006468	protein phosphorylation
0.47	GO:0045075	regulation of interleukin-12 biosynthetic process
0.46	GO:0018209	peptidyl-serine modification
0.42	GO:0007010	cytoskeleton organization
0.40	GO:0035556	intracellular signal transduction

0.67	GO:0004674	protein serine/threonine kinase activity
0.60	GO:0000287	magnesium ion binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.67

GO:0004674

tr|J9PBK3|J9PBK3_CANLF
Uncharacterized protein
Search

SETMAR

0.64	SET domain and mariner transposase fusion gene

0.77	GO:0034968	histone lysine methylation
0.45	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
0.44	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining
0.44	GO:0071157	negative regulation of cell cycle arrest
0.44	GO:0000729	DNA double-strand break processing
0.43	GO:0018027	peptidyl-lysine dimethylation
0.43	GO:0031297	replication fork processing
0.43	GO:0044774	mitotic DNA integrity checkpoint
0.43	GO:0000737	DNA catabolic process, endonucleolytic
0.42	GO:0006303	double-strand break repair via nonhomologous end joining

0.77	GO:0018024	histone-lysine N-methyltransferase activity
0.61	GO:0008270	zinc ion binding
0.45	GO:0044547	DNA topoisomerase binding
0.43	GO:0000014	single-stranded DNA endodeoxyribonuclease activity
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0003697	single-stranded DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.36	GO:0002039	p53 binding
0.33	GO:0010429	methyl-CpNpN binding
0.33	GO:0010428	methyl-CpNpG binding

0.65	GO:0005694	chromosome
0.60	GO:0005634	nucleus
0.39	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.33	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex
0.32	GO:0034708	methyltransferase complex
0.32	GO:0009507	chloroplast
0.32	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.77

EC:2.1.1.43

GO:0018024

tr|J9PBK4|J9PBK4_CANLF
Uncharacterized protein
Search

RPL23A

0.89	Ribosomal protein L23A, pseudogene 3

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000027	ribosomal large subunit assembly
0.43	GO:0008283	cell proliferation
0.39	GO:0031016	pancreas development
0.37	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0007250	activation of NF-kappaB-inducing kinase activity

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0045296	cadherin binding
0.42	GO:0003723	RNA binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.42	GO:0031932	TORC2 complex
0.41	GO:0044446	intracellular organelle part
0.39	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen

tr|J9PBK5|J9PBK5_CANLF
Uncharacterized protein
Search

tr|J9PBK6|J9PBK6_CANLF
Uncharacterized protein
Search

0.33	Tyrosine-protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.53	GO:0051463	negative regulation of cortisol secretion
0.53	GO:0060125	negative regulation of growth hormone secretion
0.52	GO:0061582	intestinal epithelial cell migration
0.52	GO:0033277	abortive mitotic cell cycle
0.52	GO:0001501	skeletal system development
0.52	GO:0036302	atrioventricular canal development
0.52	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.51	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.51	GO:0060020	Bergmann glial cell differentiation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0005158	insulin receptor binding
0.51	GO:0051428	peptide hormone receptor binding
0.50	GO:0005070	SH3/SH2 adaptor activity
0.49	GO:0030971	receptor tyrosine kinase binding
0.47	GO:0050839	cell adhesion molecule binding
0.38	GO:0031748	D1 dopamine receptor binding
0.38	GO:0043274	phospholipase binding
0.38	GO:0043560	insulin receptor substrate binding
0.36	GO:0019904	protein domain specific binding

0.44	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.75	EC:3.1.3.48	GO:0004725
0.35	KEGG:R04545	GO:0046934

tr|J9PBK7|J9PBK7_CANLF
Uncharacterized protein
Search

POLG2

0.97	Mitochondrial DNA polymerase subunit gamma-2

0.66	GO:0006260	DNA replication
0.65	GO:0070584	mitochondrion morphogenesis
0.65	GO:0032042	mitochondrial DNA metabolic process
0.65	GO:0006281	DNA repair
0.59	GO:0001701	in utero embryonic development
0.53	GO:0070150	mitochondrial glycyl-tRNA aminoacylation
0.53	GO:0022904	respiratory electron transport chain
0.53	GO:0071897	DNA biosynthetic process

0.57	GO:0042802	identical protein binding
0.55	GO:0003887	DNA-directed DNA polymerase activity
0.48	GO:0004820	glycine-tRNA ligase activity
0.35	GO:0003677	DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0042645	mitochondrial nucleoid
0.38	GO:0070062	extracellular exosome
0.37	GO:0000229	cytoplasmic chromosome

0.55

EC:2.7.7.7

GO:0003887

tr|J9PBK8|J9PBK8_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBK9|J9PBK9_CANLF
Uncharacterized protein
Search

RBBP5

0.93	RB binding protein 5, histone lysine methyltransferase complex subunit

0.77	GO:0043627	response to estrogen
0.74	GO:0051568	histone H3-K4 methylation
0.59	GO:0006974	cellular response to DNA damage stimulus

0.76	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.76	GO:0140034	methylation-dependent protein binding
0.72	GO:0042393	histone binding
0.69	GO:0044212	transcription regulatory region DNA binding

0.81	GO:0048188	Set1C/COMPASS complex
0.77	GO:0044666	MLL3/4 complex
0.74	GO:0071339	MLL1 complex
0.66	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBL0|J9PBL0_CANLF
Uncharacterized protein
Search

ZNF311

0.91	Zinc finger protein 311

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0044092	negative regulation of molecular function
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0051239	regulation of multicellular organismal process
0.34	GO:0045596	negative regulation of cell differentiation
0.34	GO:0030154	cell differentiation
0.34	GO:1902680	positive regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.38	GO:0042826	histone deacetylase binding
0.37	GO:0003682	chromatin binding
0.34	GO:0004402	histone acetyltransferase activity
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0004252	serine-type endopeptidase activity

0.42	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

EC:2.3.1.48

GO:0004402

tr|J9PBL4|J9PBL4_CANLF
Uncharacterized protein
Search

tr|J9PBL7|J9PBL7_CANLF
Uncharacterized protein
Search

FBXO42

0.95	F-box only protein 42

0.39	GO:0043043	peptide biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:0010467	gene expression
0.37	GO:0009059	macromolecule biosynthetic process

0.53	GO:0005515	protein binding
0.41	GO:0019843	rRNA binding
0.40	GO:0003735	structural constituent of ribosome

0.40

GO:0005840

ribosome

tr|J9PBL8|J9PBL8_CANLF
Uncharacterized protein
Search

EIF4E2

0.78	Eukaryotic translation initiation factor 4E

0.72	GO:0006413	translational initiation
0.49	GO:0001701	in utero embryonic development
0.47	GO:0017148	negative regulation of translation
0.34	GO:0055114	oxidation-reduction process

0.73	GO:0003743	translation initiation factor activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0020037	heme binding
0.35	GO:0005506	iron ion binding
0.34	GO:0000339	RNA cap binding

0.51	GO:0005845	mRNA cap binding complex
0.49	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

GO:0016705

tr|J9PBM2|J9PBM2_CANLF
Uncharacterized protein
Search

0.11	Doublesex-and mab-3-related transcription factor C2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0007290	spermatid nucleus elongation
0.45	GO:1900114	positive regulation of histone H3-K9 trimethylation
0.45	GO:1900111	positive regulation of histone H3-K9 dimethylation
0.44	GO:0007141	male meiosis I
0.36	GO:0007548	sex differentiation
0.36	GO:0010467	gene expression
0.36	GO:0009059	macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0043565	sequence-specific DNA binding
0.50	GO:0046872	metal ion binding
0.41	GO:0042803	protein homodimerization activity
0.36	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.45	GO:0001741	XY body
0.36	GO:0005840	ribosome

tr|J9PBM3|J9PBM3_CANLF
Uncharacterized protein
Search

tr|J9PBM4|J9PBM4_CANLF
Uncharacterized protein
Search

RFWD3

0.91	RING finger and WD repeat domain-containing protein 3

0.83	GO:0036297	interstrand cross-link repair
0.73	GO:0016567	protein ubiquitination
0.72	GO:2000001	regulation of DNA damage checkpoint
0.71	GO:0031571	mitotic G1 DNA damage checkpoint
0.69	GO:0031297	replication fork processing
0.68	GO:0010212	response to ionizing radiation
0.64	GO:0000724	double-strand break repair via homologous recombination
0.37	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0006468	protein phosphorylation

0.75	GO:0097371	MDM2/MDM4 family protein binding
0.74	GO:0004842	ubiquitin-protein transferase activity
0.70	GO:0002039	p53 binding
0.36	GO:0004871	signal transducer activity
0.36	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0035861	site of double-strand break
0.61	GO:0005634	nucleus
0.57	GO:0031974	membrane-enclosed lumen

0.74

KEGG:R03876

GO:0004842

tr|J9PBM5|J9PBM5_CANLF
Uncharacterized protein
Search

0.10	Putative conserved plasma membrane protein (Fragment)

0.35	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse
0.34	GO:0007218	neuropeptide signaling pathway
0.34	GO:0030100	regulation of endocytosis
0.34	GO:0070588	calcium ion transmembrane transport
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0007018	microtubule-based movement
0.33	GO:0050790	regulation of catalytic activity
0.33	GO:0006897	endocytosis
0.30	GO:0008152	metabolic process

0.34	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0051015	actin filament binding
0.33	GO:0030234	enzyme regulator activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005891	voltage-gated calcium channel complex
0.33	GO:1905369	endopeptidase complex
0.33	GO:0016459	myosin complex

0.33

GO:0016758

tr|J9PBM6|J9PBM6_CANLF
Uncharacterized protein
Search

RABIF

0.95	RAB interacting factor

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.49	GO:0006892	post-Golgi vesicle-mediated transport
0.43	GO:0061865	polarized secretion of basement membrane proteins in epithelium
0.36	GO:0015031	protein transport
0.34	GO:0061025	membrane fusion
0.33	GO:0007017	microtubule-based process
0.33	GO:0007010	cytoskeleton organization
0.32	GO:0000956	nuclear-transcribed mRNA catabolic process
0.32	GO:0000398	mRNA splicing, via spliceosome

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.48	GO:0008270	zinc ion binding
0.40	GO:0017137	Rab GTPase binding
0.33	GO:0003677	DNA binding
0.33	GO:0005200	structural constituent of cytoskeleton
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.41	GO:0045178	basal part of cell
0.35	GO:0071944	cell periphery
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0099512	supramolecular fiber
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.32	GO:1990904	ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|J9PBM7|J9PBM7_CANLF
Uncharacterized protein
Search

STAG2

0.94	cohesin subunit SA-2

0.86	GO:0032876	negative regulation of DNA endoreduplication
0.85	GO:1901673	regulation of mitotic spindle assembly
0.78	GO:0007062	sister chromatid cohesion
0.49	GO:0019827	stem cell population maintenance
0.46	GO:0006366	transcription by RNA polymerase II
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0051321	meiotic cell cycle
0.41	GO:0051301	cell division
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process

0.48	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding
0.34	GO:0003735	structural constituent of ribosome

0.85	GO:0097431	mitotic spindle pole
0.84	GO:0016363	nuclear matrix
0.84	GO:0008278	cohesin complex
0.72	GO:0000785	chromatin
0.44	GO:0000775	chromosome, centromeric region
0.42	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|J9PBM8|J9PBM8_CANLF
Uncharacterized protein
Search

RGS8

0.97	Regulator of G protein signaling 8

0.70	GO:0043547	positive regulation of GTPase activity
0.65	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0060159	regulation of dopamine receptor signaling pathway
0.39	GO:0009968	negative regulation of signal transduction
0.39	GO:0095500	acetylcholine receptor signaling pathway
0.34	GO:0008591	regulation of Wnt signaling pathway, calcium modulating pathway
0.33	GO:0061053	somite development
0.33	GO:0007601	visual perception

0.70	GO:0005096	GTPase activator activity
0.35	GO:0001965	G-protein alpha-subunit binding
0.33	GO:0005516	calmodulin binding

0.40	GO:0032809	neuronal cell body membrane
0.39	GO:0043204	perikaryon
0.38	GO:0030425	dendrite
0.38	GO:0005737	cytoplasm
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0005634	nucleus
0.33	GO:0045121	membrane raft
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBN1|J9PBN1_CANLF
Uncharacterized protein
Search

0.40	Protein tyrosine phosphatase, non-receptor type 18 (Fragment)

tr|J9PBN2|J9PBN2_CANLF
Uncharacterized protein
Search

FBXL17

0.85	F-box and leucine rich repeat protein 17

0.50	GO:0007009	plasma membrane organization
0.50	GO:0006886	intracellular protein transport
0.42	GO:0043486	histone exchange
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.35	GO:0006518	peptide metabolic process
0.35	GO:0090150	establishment of protein localization to membrane
0.35	GO:0043604	amide biosynthetic process

0.55	GO:0008536	Ran GTPase binding
0.47	GO:0003779	actin binding
0.36	GO:0003735	structural constituent of ribosome
0.35	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005622	intracellular
0.36	GO:0043226	organelle
0.35	GO:1990904	ribonucleoprotein complex
0.34	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

tr|J9PBN4|J9PBN4_CANLF
Uncharacterized protein
Search

tr|J9PBN9|J9PBN9_CANLF
Uncharacterized protein
Search

0.74	Zinc finger protein 786

0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0045773	positive regulation of axon extension
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0007411	axon guidance

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding

0.46	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|J9PBP0|J9PBP0_CANLF
5-hydroxytryptamine receptor 2C
Search

HTR2C

0.97	5-hydroxytryptamine (Serotonin) receptor 2C long isoform

0.78	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.77	GO:0007631	feeding behavior
0.75	GO:0007626	locomotory behavior
0.63	GO:0043397	regulation of corticotropin-releasing hormone secretion
0.62	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.60	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.60	GO:0001662	behavioral fear response
0.59	GO:0032098	regulation of appetite
0.59	GO:0051209	release of sequestered calcium ion into cytosol
0.59	GO:0031644	regulation of neurological system process

0.78	GO:0099589	serotonin receptor activity
0.75	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.75	GO:0008227	G-protein coupled amine receptor activity
0.64	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
0.61	GO:0051378	serotonin binding
0.33	GO:0005515	protein binding

0.62	GO:0005887	integral component of plasma membrane
0.37	GO:0009897	external side of plasma membrane
0.32	GO:0005622	intracellular

tr|J9PBP1|J9PBP1_CANLF
Uncharacterized protein
Search

tr|J9PBP2|J9PBP2_CANLF
Uncharacterized protein
Search

tr|J9PBP3|J9PBP3_CANLF
Katanin p60 ATPase-containing subunit A-like 2
Search

KATNAL2

0.93	Katanin p60 ATPase-containing subunit A-like 2

0.78

GO:0051013

microtubule severing

0.79	GO:0008568	microtubule-severing ATPase activity
0.68	GO:0008017	microtubule binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0000922	spindle pole
0.68	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.6.4.3

GO:0008568

tr|J9PBP4|J9PBP4_CANLF
Uncharacterized protein
Search

tr|J9PBP5|J9PBP5_CANLF
Uncharacterized protein
Search

tr|J9PBP6|J9PBP6_CANLF
Uncharacterized protein
Search

MSI1

0.93	Musashi RNA binding protein 1

0.42	GO:0007417	central nervous system development
0.36	GO:0050482	arachidonic acid secretion
0.35	GO:0030855	epithelial cell differentiation
0.35	GO:0016042	lipid catabolic process
0.35	GO:0009725	response to hormone
0.34	GO:0006644	phospholipid metabolic process

0.59	GO:0003723	RNA binding
0.51	GO:0042802	identical protein binding
0.36	GO:0004623	phospholipase A2 activity
0.34	GO:0005509	calcium ion binding

0.55	GO:0005844	polysome
0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.36

EC:3.1.1.4

GO:0004623

tr|J9PBP7|J9PBP7_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|J9PBP8|J9PBP8_CANLF
Uncharacterized protein
Search

PCP4

0.97	Brain-specific polypeptide PEP-19

0.62	GO:0099004	calmodulin dependent kinase signaling pathway
0.56	GO:0045666	positive regulation of neuron differentiation
0.38	GO:1904009	cellular response to monosodium glutamate
0.37	GO:0033603	positive regulation of dopamine secretion
0.36	GO:0001649	osteoblast differentiation
0.36	GO:0043524	negative regulation of neuron apoptotic process
0.36	GO:0031346	positive regulation of cell projection organization
0.36	GO:0010975	regulation of neuron projection development
0.36	GO:0006469	negative regulation of protein kinase activity
0.35	GO:0006970	response to osmotic stress

0.79	GO:0005516	calmodulin binding
0.50	GO:0005509	calcium ion binding
0.33	GO:0003723	RNA binding

0.45	GO:0043234	protein complex
0.36	GO:0005883	neurofilament
0.36	GO:0005829	cytosol
0.36	GO:0030424	axon
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|K9J6N9|K9J6N9_CANLF
U1 small nuclear ribonucleoprotein C
Search

SNRPC

0.74	Small nuclear ribonucleoprotein polypeptide C variant (Fragment)

0.80	GO:0000387	spliceosomal snRNP assembly
0.79	GO:0000395	mRNA 5'-splice site recognition
0.41	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.76	GO:0030619	U1 snRNA binding
0.67	GO:0003729	mRNA binding
0.62	GO:0008270	zinc ion binding
0.51	GO:0030627	pre-mRNA 5'-splice site binding
0.50	GO:0003727	single-stranded RNA binding
0.49	GO:0042803	protein homodimerization activity
0.39	GO:1990446	U1 snRNP binding
0.32	GO:0003677	DNA binding

0.81	GO:0005685	U1 snRNP
0.77	GO:0000243	commitment complex
0.76	GO:0071010	prespliceosome
0.57	GO:0019013	viral nucleocapsid
0.53	GO:0015030	Cajal body

tr|K9J6P0|K9J6P0_CANLF
Nuclear receptor subfamily 4 group A member 1
Search

0.88	Nuclear receptor subfamily 4 group A member 2 variant TINUR

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.52	GO:0045444	fat cell differentiation
0.50	GO:0043066	negative regulation of apoptotic process
0.49	GO:0051866	general adaptation syndrome

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.51	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0035259	glucocorticoid receptor binding
0.48	GO:0046982	protein heterodimerization activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.42	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.42	GO:0044446	intracellular organelle part
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0005829	cytosol
0.41	GO:0012505	endomembrane system
0.39	GO:0031090	organelle membrane
0.39	GO:0031975	envelope

tr|K9J6P1|K9J6P1_CANLF
Uncharacterized protein
Search

SMN1

0.87	Survival of motor neuron

0.69	GO:0006397	mRNA processing
0.49	GO:0007399	nervous system development
0.48	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.48	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.48	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.48	GO:0000904	cell morphogenesis involved in differentiation
0.48	GO:0051960	regulation of nervous system development
0.48	GO:0060284	regulation of cell development
0.47	GO:0007019	microtubule depolymerization
0.47	GO:0033120	positive regulation of RNA splicing

0.59	GO:0003723	RNA binding
0.39	GO:0042802	identical protein binding
0.37	GO:0017134	fibroblast growth factor binding

0.61	GO:0005634	nucleus
0.50	GO:0032797	SMN complex
0.49	GO:0043204	perikaryon
0.49	GO:0034719	SMN-Sm protein complex
0.49	GO:0030018	Z disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0043005	neuron projection
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0005829	cytosol
0.41	GO:0044446	intracellular organelle part

tr|K9J6P2|K9J6P2_CANLF
HORMA domain-containing protein 1
Search

HORMAD1

0.94	LOW QUALITY PROTEIN: HORMA domain-containing protein 2

0.85	GO:0051177	meiotic sister chromatid cohesion
0.83	GO:0060629	regulation of homologous chromosome segregation
0.80	GO:0051598	meiotic recombination checkpoint
0.78	GO:0042138	meiotic DNA double-strand break formation
0.78	GO:0007130	synaptonemal complex assembly
0.75	GO:0001824	blastocyst development
0.73	GO:0048477	oogenesis
0.72	GO:0007283	spermatogenesis

0.36

GO:0005515

protein binding

0.82	GO:0000795	synaptonemal complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|K9J8H5|K9J8H5_CANLF
Uncharacterized protein
Search

AKR1D1

0.97	3-oxo-5-beta-steroid 4-dehydrogenase

0.59	GO:0006707	cholesterol catabolic process
0.58	GO:0006699	bile acid biosynthetic process
0.58	GO:0008209	androgen metabolic process
0.58	GO:0008207	C21-steroid hormone metabolic process
0.56	GO:0007586	digestion
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0030573	bile acid catabolic process
0.34	GO:0008284	positive regulation of cell proliferation
0.34	GO:0042446	hormone biosynthetic process
0.34	GO:0006836	neurotransmitter transport

0.54	GO:0016491	oxidoreductase activity
0.35	GO:0005496	steroid binding
0.34	GO:0005328	neurotransmitter:sodium symporter activity

0.48	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.54

GO:0016491

tr|L7N047|L7N047_CANLF
Uncharacterized protein
Search

SERF2

0.68	Huntingtin interacting protein K

0.46	GO:0000413	protein peptidyl-prolyl isomerization
0.41	GO:0007399	nervous system development

0.46	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.45	GO:0005515	protein binding

0.52	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.46

EC:5.2.1.8

GO:0003755

tr|L7N048|L7N048_CANLF
Uncharacterized protein
Search

ADGB

0.95	Androglobin

0.59	GO:0006508	proteolysis
0.36	GO:0015671	oxygen transport

0.78	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.44	GO:0020037	heme binding
0.36	GO:0005344	oxygen carrier activity

0.44	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

tr|L7N050|L7N050_CANLF
Uncharacterized protein
Search

0.62	Epididymis secretory protein Li 103

0.53	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0010638	positive regulation of organelle organization
0.52	GO:0042026	protein refolding
0.51	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.51	GO:1903214	regulation of protein targeting to mitochondrion
0.51	GO:0090316	positive regulation of intracellular protein transport
0.47	GO:0010968	regulation of microtubule nucleation
0.46	GO:1901673	regulation of mitotic spindle assembly
0.44	GO:0032273	positive regulation of protein polymerization
0.44	GO:1902905	positive regulation of supramolecular fiber organization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0031072	heat shock protein binding
0.47	GO:0051082	unfolded protein binding
0.41	GO:0055131	C3HC4-type RING finger domain binding
0.41	GO:0031249	denatured protein binding
0.41	GO:0001106	RNA polymerase II transcription corepressor activity

0.54	GO:0002199	zona pellucida receptor complex
0.50	GO:0044297	cell body
0.50	GO:0008180	COP9 signalosome
0.46	GO:0005829	cytosol
0.43	GO:0005813	centrosome
0.41	GO:0072562	blood microparticle
0.40	GO:0016235	aggresome
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0005814	centriole
0.39	GO:0070062	extracellular exosome

0.35	EC:6.1.1.9	GO:0004832
0.35	KEGG:R03665	GO:0004832

tr|L7N052|L7N052_CANLF
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.60	GO:0050922	negative regulation of chemotaxis
0.60	GO:0007498	mesoderm development
0.60	GO:0072089	stem cell proliferation
0.60	GO:0060322	head development
0.60	GO:0001649	osteoblast differentiation
0.59	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.59	GO:0061387	regulation of extent of cell growth
0.59	GO:0048640	negative regulation of developmental growth

0.73	GO:0005102	receptor binding
0.55	GO:0019904	protein domain specific binding
0.55	GO:0030545	receptor regulator activity
0.53	GO:0039706	co-receptor binding
0.48	GO:0003713	transcription coactivator activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.53	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.50	GO:0005615	extracellular space
0.47	GO:0009986	cell surface
0.38	GO:0005788	endoplasmic reticulum lumen
0.37	GO:1990909	Wnt signalosome
0.37	GO:0005796	Golgi lumen
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0030139	endocytic vesicle

tr|L7N053|L7N053_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N054|L7N054_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N055|L7N055_CANLF
Adenosylhomocysteinase
Search

AHCYL2

0.55	Adenosylhomocysteinase

0.72	GO:0006730	one-carbon metabolic process
0.47	GO:0033353	S-adenosylmethionine cycle
0.39	GO:0042045	epithelial fluid transport
0.39	GO:0010765	positive regulation of sodium ion transport
0.39	GO:0038166	angiotensin-activated signaling pathway
0.39	GO:0031440	regulation of mRNA 3'-end processing
0.38	GO:0006611	protein export from nucleus
0.38	GO:0044070	regulation of anion transport
0.38	GO:0051592	response to calcium ion
0.38	GO:0032412	regulation of ion transmembrane transporter activity

0.80	GO:0004013	adenosylhomocysteinase activity
0.37	GO:0042802	identical protein binding
0.32	GO:0003723	RNA binding

0.47	GO:0043005	neuron projection
0.47	GO:0005829	cytosol
0.40	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0012505	endomembrane system
0.34	GO:0016324	apical plasma membrane
0.34	GO:0070062	extracellular exosome

0.80

EC:3.3.1.1

GO:0004013

tr|L7N056|L7N056_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.48	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.47	GO:0001963	synaptic transmission, dopaminergic
0.47	GO:0048148	behavioral response to cocaine
0.47	GO:0014059	regulation of dopamine secretion
0.47	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.47	GO:0007194	negative regulation of adenylate cyclase activity
0.47	GO:0048149	behavioral response to ethanol

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.47	GO:0035240	dopamine binding
0.43	GO:0030594	neurotransmitter receptor activity
0.35	GO:0005549	odorant binding

0.56	GO:0005886	plasma membrane
0.46	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

tr|L7N057|L7N057_CANLF
Uncharacterized protein
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:1903955	positive regulation of protein targeting to mitochondrion

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N058|L7N058_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:1903955	positive regulation of protein targeting to mitochondrion

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N060|L7N060_CANLF
Uncharacterized protein
Search

RPL37

0.72	Ribosomal protein L37

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.63	GO:0019843	rRNA binding
0.62	GO:0003735	structural constituent of ribosome
0.52	GO:0046872	metal ion binding
0.34	GO:0019838	growth factor binding

0.60	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|L7N062|L7N062_CANLF
Uncharacterized protein
Search

RP9

0.97	Retinitis pigmentosa 9 (autosomal dominant)

0.74	GO:0008380	RNA splicing
0.49	GO:0050890	cognition
0.34	GO:0098789	pre-mRNA cleavage required for polyadenylation
0.34	GO:0006378	mRNA polyadenylation

0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.45	GO:0005829	cytosol
0.43	GO:0005785	signal recognition particle receptor complex
0.43	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

tr|L7N064|L7N064_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N065|L7N065_CANLF
40S ribosomal protein S24
Search

RPS24

0.68	40S ribosomal protein S24

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.46	GO:0042274	ribosomal small subunit biogenesis
0.44	GO:0016072	rRNA metabolic process
0.42	GO:0034101	erythrocyte homeostasis
0.35	GO:0048513	animal organ development
0.34	GO:0061008	hepaticobiliary system development
0.34	GO:0031099	regeneration

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0031369	translation initiation factor binding
0.34	GO:0032403	protein complex binding
0.33	GO:0003743	translation initiation factor activity

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

tr|L7N066|L7N066_CANLF
Uncharacterized protein
Search

HNRNPA1

0.85	Heterogeneous nuclear ribonucleoprotein A1

0.51	GO:1903936	cellular response to sodium arsenite
0.46	GO:0051028	mRNA transport
0.46	GO:0032211	negative regulation of telomere maintenance via telomerase
0.46	GO:0032212	positive regulation of telomere maintenance via telomerase
0.45	GO:0008380	RNA splicing
0.45	GO:0042149	cellular response to glucose starvation
0.45	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.44	GO:0006397	mRNA processing
0.42	GO:0051168	nuclear export
0.42	GO:0051170	nuclear import

0.59	GO:0003723	RNA binding
0.47	GO:0098505	G-rich strand telomeric DNA binding
0.43	GO:0019904	protein domain specific binding
0.39	GO:0036310	annealing helicase activity
0.37	GO:0042802	identical protein binding
0.36	GO:0008134	transcription factor binding

0.64	GO:0019013	viral nucleocapsid
0.57	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0044428	nuclear part
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:1902494	catalytic complex
0.38	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|L7N067|L7N067_CANLF
Uncharacterized protein
Search

0.95	GTPase IMAP family member 5

0.38	GO:0033955	mitochondrial DNA inheritance
0.38	GO:0002729	positive regulation of natural killer cell cytokine production
0.38	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.38	GO:0045588	positive regulation of gamma-delta T cell differentiation
0.38	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin
0.37	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.37	GO:0045838	positive regulation of membrane potential
0.37	GO:0050995	negative regulation of lipid catabolic process
0.37	GO:0043011	myeloid dendritic cell differentiation
0.37	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding

0.49	GO:0005811	lipid droplet
0.42	GO:0005741	mitochondrial outer membrane
0.41	GO:0005764	lysosome
0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0005829	cytosol
0.35	GO:0000139	Golgi membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0031224	intrinsic component of membrane

tr|L7N070|L7N070_CANLF
Uncharacterized protein
Search

0.97	Felis catus cytochrome P450, family 2, subfamily A, polypeptide 13

0.53	GO:0055114	oxidation-reduction process
0.53	GO:0019373	epoxygenase P450 pathway

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.53	GO:0008392	arachidonic acid epoxygenase activity
0.51	GO:0008395	steroid hydroxylase activity
0.39	GO:0005515	protein binding

0.30

GO:0031224

intrinsic component of membrane

0.78

GO:0016712

tr|L7N072|L7N072_CANLF
Uncharacterized protein
Search

0.40	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N073|L7N073_CANLF
Uncharacterized protein
Search

0.61	Zinc finger protein 793

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:1900112	regulation of histone H3-K9 trimethylation
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0043392	negative regulation of DNA binding

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.33	GO:0003714	transcription corepressor activity

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0043233	organelle lumen
0.34	GO:0043228	non-membrane-bounded organelle

tr|L7N074|L7N074_CANLF
Uncharacterized protein
Search

0.67	Heterogeneous nuclear ribonucleoprotein A1 (Fragment)

0.51	GO:1903936	cellular response to sodium arsenite
0.47	GO:0032211	negative regulation of telomere maintenance via telomerase
0.46	GO:0032212	positive regulation of telomere maintenance via telomerase
0.46	GO:0042149	cellular response to glucose starvation
0.46	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.44	GO:0051028	mRNA transport
0.43	GO:0008380	RNA splicing
0.43	GO:0051168	nuclear export
0.43	GO:0051170	nuclear import
0.42	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.48	GO:0098505	G-rich strand telomeric DNA binding
0.43	GO:0019904	protein domain specific binding
0.36	GO:0042802	identical protein binding
0.35	GO:0004930	G-protein coupled receptor activity

0.64	GO:0019013	viral nucleocapsid
0.57	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0044428	nuclear part
0.44	GO:0031974	membrane-enclosed lumen
0.39	GO:1902494	catalytic complex
0.37	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0048475	coated membrane
0.34	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|L7N075|L7N075_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0015671	oxygen transport

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005344	oxygen carrier activity
0.33	GO:0019825	oxygen binding
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.55	GO:0005886	plasma membrane
0.34	GO:0005833	hemoglobin complex
0.30	GO:0031224	intrinsic component of membrane

tr|L7N076|L7N076_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N079|L7N079_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N080|L7N080_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0008270	zinc ion binding

0.55	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

tr|L7N081|L7N081_CANLF
Olfactory receptor
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N082|L7N082_CANLF
Olfactory receptor
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N083|L7N083_CANLF
Olfactory receptor
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N085|L7N085_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N086|L7N086_CANLF
Uncharacterized protein
Search

0.96	Olfactory receptor family 56 subfamily A member 3

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.50	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.49	GO:0001963	synaptic transmission, dopaminergic
0.49	GO:0048148	behavioral response to cocaine
0.49	GO:0014059	regulation of dopamine secretion
0.49	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.49	GO:0007194	negative regulation of adenylate cyclase activity
0.49	GO:0048149	behavioral response to ethanol

0.76	GO:0004984	olfactory receptor activity
0.68	GO:0004930	G-protein coupled receptor activity
0.49	GO:0035240	dopamine binding
0.45	GO:0030594	neurotransmitter receptor activity

0.53	GO:0005886	plasma membrane
0.48	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

tr|L7N087|L7N087_CANLF
Uncharacterized protein
Search

0.97	Olfactory receptor family 56 subfamily A member 1

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.53	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.52	GO:0001963	synaptic transmission, dopaminergic
0.52	GO:0048148	behavioral response to cocaine
0.52	GO:0014059	regulation of dopamine secretion
0.52	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.52	GO:0007194	negative regulation of adenylate cyclase activity
0.52	GO:0048149	behavioral response to ethanol

0.76	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity
0.52	GO:0035240	dopamine binding
0.47	GO:0030594	neurotransmitter receptor activity

0.54	GO:0005886	plasma membrane
0.51	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

tr|L7N088|L7N088_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N089|L7N089_CANLF
Uncharacterized protein
Search

EP400

0.96	E1A-binding protein p400 isoform E

0.57	GO:0043968	histone H2A acetylation
0.56	GO:0043967	histone H4 acetylation

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:1990405	protein antigen binding
0.39	GO:0003682	chromatin binding
0.35	GO:0004386	helicase activity
0.34	GO:0003677	DNA binding

0.56	GO:0000812	Swr1 complex
0.54	GO:0035267	NuA4 histone acetyltransferase complex
0.54	GO:0016607	nuclear speck

tr|L7N091|L7N091_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0043666	regulation of phosphoprotein phosphatase activity

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.34	GO:0019888	protein phosphatase regulator activity

0.54	GO:0005886	plasma membrane
0.34	GO:0000159	protein phosphatase type 2A complex
0.30	GO:0031224	intrinsic component of membrane

tr|L7N092|L7N092_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.40	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N094|L7N094_CANLF
Uncharacterized protein
Search

0.88	keratin, type II cytoskeletal 2 epidermal

0.53	GO:0045103	intermediate filament-based process
0.52	GO:0043588	skin development
0.52	GO:0008544	epidermis development
0.49	GO:0007010	cytoskeleton organization
0.48	GO:0043473	pigmentation
0.47	GO:0030154	cell differentiation
0.47	GO:0048732	gland development
0.46	GO:0060429	epithelium development
0.43	GO:0032980	keratinocyte activation
0.43	GO:0030097	hemopoiesis

0.62	GO:0005198	structural molecule activity
0.43	GO:0097110	scaffold protein binding
0.38	GO:0008092	cytoskeletal protein binding
0.33	GO:0046982	protein heterodimerization activity

0.83	GO:0045095	keratin filament
0.41	GO:0001533	cornified envelope
0.40	GO:0070062	extracellular exosome
0.39	GO:0009986	cell surface
0.37	GO:0005739	mitochondrion
0.36	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0036338	viral membrane

tr|L7N099|L7N099_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.49	GO:0005549	odorant binding

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0A0|L7N0A0_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.53	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0A1|L7N0A1_CANLF
Ribosomal protein L37
Search

RPL37

0.73	Ribosomal protein L37

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.63	GO:0019843	rRNA binding
0.62	GO:0003735	structural constituent of ribosome
0.52	GO:0046872	metal ion binding
0.34	GO:0019838	growth factor binding

0.60	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0A2|L7N0A2_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.53	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0A3|L7N0A3_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.36	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0A4|L7N0A4_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0007210	serotonin receptor signaling pathway
0.38	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.38	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.38	GO:0001963	synaptic transmission, dopaminergic
0.38	GO:0048148	behavioral response to cocaine
0.38	GO:0014059	regulation of dopamine secretion
0.38	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.38	GO:0007194	negative regulation of adenylate cyclase activity

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.50	GO:0099589	serotonin receptor activity
0.48	GO:0030594	neurotransmitter receptor activity
0.38	GO:0035240	dopamine binding
0.36	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.38	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

tr|L7N0A5|L7N0A5_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0007210	serotonin receptor signaling pathway
0.38	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.38	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.38	GO:0001963	synaptic transmission, dopaminergic
0.38	GO:0048148	behavioral response to cocaine
0.38	GO:0014059	regulation of dopamine secretion
0.38	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.38	GO:0007194	negative regulation of adenylate cyclase activity

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.50	GO:0099589	serotonin receptor activity
0.48	GO:0030594	neurotransmitter receptor activity
0.38	GO:0035240	dopamine binding
0.34	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.38	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

tr|L7N0A6|L7N0A6_CANLF
Olfactory receptor
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.52	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0A7|L7N0A7_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0A8|L7N0A8_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0A9|L7N0A9_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0055114	oxidation-reduction process

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.32	GO:0016491	oxidoreductase activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

tr|L7N0B0|L7N0B0_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0B1|L7N0B1_CANLF
40S ribosomal protein S24
Search

RPS24

0.69	40S ribosomal protein S24

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.46	GO:0042274	ribosomal small subunit biogenesis
0.44	GO:0016072	rRNA metabolic process
0.42	GO:0034101	erythrocyte homeostasis
0.35	GO:0048513	animal organ development
0.34	GO:0061008	hepaticobiliary system development
0.34	GO:0031099	regeneration

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0031369	translation initiation factor binding
0.34	GO:0032403	protein complex binding
0.33	GO:0003743	translation initiation factor activity

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

tr|L7N0B2|L7N0B2_CANLF
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.45	GO:0071353	cellular response to interleukin-4
0.36	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0021634	optic nerve formation
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0018410	C-terminal protein amino acid modification
0.34	GO:0051301	cell division

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0003725	double-stranded RNA binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0046872	metal ion binding

0.73	GO:0005874	microtubule
0.48	GO:0043209	myelin sheath
0.48	GO:0005737	cytoplasm
0.43	GO:0035770	ribonucleoprotein granule
0.42	GO:0031982	vesicle
0.40	GO:0012505	endomembrane system
0.39	GO:0045121	membrane raft
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space
0.34	GO:0030496	midbody

tr|L7N0B3|L7N0B3_CANLF
Uncharacterized protein
Search

0.82	Disintegrin and metalloproteinase domain-containing protein 1

0.60	GO:0006508	proteolysis
0.60	GO:0007229	integrin-mediated signaling pathway
0.39	GO:0007338	single fertilization
0.39	GO:0009988	cell-cell recognition
0.37	GO:0032501	multicellular organismal process
0.36	GO:0051094	positive regulation of developmental process
0.36	GO:0051240	positive regulation of multicellular organismal process
0.36	GO:0034239	regulation of macrophage fusion
0.36	GO:0042117	monocyte activation
0.36	GO:0033631	cell-cell adhesion mediated by integrin

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.41	GO:0017124	SH3 domain binding
0.35	GO:0043236	laminin binding
0.35	GO:0005178	integrin binding
0.35	GO:0005518	collagen binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.33	GO:0004672	protein kinase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.38	GO:0045121	membrane raft
0.37	GO:0005794	Golgi apparatus
0.34	GO:0005615	extracellular space
0.34	GO:0005654	nucleoplasm
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.70

EC:3.4.24

GO:0004222

tr|L7N0B5|L7N0B5_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0B6|L7N0B6_CANLF
Uncharacterized protein
Search

DONSON

0.95	Downstream neighbor of SON

0.79	GO:0007095	mitotic G2 DNA damage checkpoint
0.77	GO:0048478	replication fork protection
0.63	GO:0033260	nuclear DNA replication
0.44	GO:0048856	anatomical structure development
0.44	GO:0032501	multicellular organismal process
0.42	GO:0006277	DNA amplification
0.39	GO:0008283	cell proliferation
0.39	GO:0019953	sexual reproduction
0.39	GO:0003006	developmental process involved in reproduction
0.38	GO:0030154	cell differentiation

0.36	GO:0005515	protein binding
0.35	GO:0016491	oxidoreductase activity
0.35	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism

0.68	GO:0030894	replisome
0.60	GO:0005634	nucleus
0.34	GO:0043209	myelin sheath
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016491

tr|L7N0B8|L7N0B8_CANLF
Uncharacterized protein
Search

CBR1

0.57	Carbonyl reductase 1

0.51	GO:0055114	oxidation-reduction process
0.50	GO:0050890	cognition
0.48	GO:0042373	vitamin K metabolic process
0.42	GO:0030855	epithelial cell differentiation
0.42	GO:1901662	quinone catabolic process
0.40	GO:0042374	phylloquinone metabolic process
0.39	GO:0009111	vitamin catabolic process
0.38	GO:0017144	drug metabolic process
0.37	GO:0006692	prostanoid metabolic process
0.35	GO:1901523	icosanoid catabolic process

0.59	GO:0004090	carbonyl reductase (NADPH) activity
0.49	GO:0070402	NADPH binding
0.43	GO:0047021	15-hydroxyprostaglandin dehydrogenase (NADP+) activity
0.43	GO:0050221	prostaglandin-E2 9-reductase activity
0.40	GO:0000253	3-keto sterol reductase activity
0.40	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.35	GO:0005515	protein binding
0.34	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity
0.33	GO:0003735	structural constituent of ribosome

0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005902	microvillus
0.33	GO:0005840	ribosome
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.59	EC:1.1.1.184	GO:0004090
0.43	KEGG:R04552	GO:0047021

tr|L7N0B9|L7N0B9_CANLF
Uncharacterized protein
Search

0.75	Carbonyl reductase

0.52	GO:0055114	oxidation-reduction process
0.50	GO:0050890	cognition
0.48	GO:0042373	vitamin K metabolic process
0.42	GO:0030855	epithelial cell differentiation
0.42	GO:1901662	quinone catabolic process
0.40	GO:0042374	phylloquinone metabolic process
0.39	GO:0009111	vitamin catabolic process
0.39	GO:0017144	drug metabolic process
0.36	GO:0006692	prostanoid metabolic process
0.35	GO:1901523	icosanoid catabolic process

0.59	GO:0004090	carbonyl reductase (NADPH) activity
0.49	GO:0070402	NADPH binding
0.44	GO:0047021	15-hydroxyprostaglandin dehydrogenase (NADP+) activity
0.44	GO:0050221	prostaglandin-E2 9-reductase activity
0.40	GO:0000253	3-keto sterol reductase activity
0.39	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.35	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.34	GO:0005902	microvillus
0.33	GO:0005840	ribosome
0.32	GO:0005886	plasma membrane

0.59	EC:1.1.1.184	GO:0004090
0.44	KEGG:R04552	GO:0047021

tr|L7N0C0|L7N0C0_CANLF
Uncharacterized protein
Search

GABRB2

0.90	Gamma-aminobutyric acid A receptor

0.61	GO:0060384	innervation
0.60	GO:0090102	cochlea development
0.60	GO:0060119	inner ear receptor cell development
0.59	GO:0007165	signal transduction
0.59	GO:0034220	ion transmembrane transport
0.59	GO:0043524	negative regulation of neuron apoptotic process
0.57	GO:0007605	sensory perception of sound
0.51	GO:0071420	cellular response to histamine
0.45	GO:0006821	chloride transport
0.45	GO:0060021	palate development

0.81	GO:0004890	GABA-A receptor activity
0.73	GO:0005230	extracellular ligand-gated ion channel activity
0.46	GO:0099095	ligand-gated anion channel activity
0.46	GO:0005254	chloride channel activity
0.43	GO:0022835	transmitter-gated channel activity
0.42	GO:0042802	identical protein binding
0.35	GO:0035612	AP-2 adaptor complex binding

0.54	GO:1902711	GABA-A receptor complex
0.54	GO:0005886	plasma membrane
0.45	GO:0098794	postsynapse
0.41	GO:0034707	chloride channel complex
0.40	GO:0030054	cell junction
0.39	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.35	GO:0060077	inhibitory synapse
0.35	GO:0043195	terminal bouton

tr|L7N0C1|L7N0C1_CANLF
Uncharacterized protein
Search

0.97	IQ domain-containing protein F5

0.63	GO:2000344	positive regulation of acrosome reaction
0.62	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.75	GO:0005516	calmodulin binding
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0003676	nucleic acid binding

0.66	GO:0001669	acrosomal vesicle
0.34	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|L7N0C2|L7N0C2_CANLF
Uncharacterized protein
Search

HNRNPA1

0.84	Heterogeneous nuclear ribonucleoprotein A1

0.53	GO:1903936	cellular response to sodium arsenite
0.48	GO:0032211	negative regulation of telomere maintenance via telomerase
0.48	GO:0032212	positive regulation of telomere maintenance via telomerase
0.48	GO:0042149	cellular response to glucose starvation
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.44	GO:0051168	nuclear export
0.44	GO:0051170	nuclear import
0.43	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.49	GO:0098505	G-rich strand telomeric DNA binding
0.45	GO:0019904	protein domain specific binding
0.38	GO:0036310	annealing helicase activity
0.38	GO:0042802	identical protein binding
0.36	GO:0008134	transcription factor binding

0.64	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0044428	nuclear part
0.45	GO:0031974	membrane-enclosed lumen
0.40	GO:1902494	catalytic complex
0.39	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.34	GO:0048475	coated membrane
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0C3|L7N0C3_CANLF
Histone H2B
Search

tr|L7N0C4|L7N0C4_CANLF
Uncharacterized protein
Search

REG4

0.97	Regenerating islet-derived protein 4

0.42	GO:0008284	positive regulation of cell proliferation
0.42	GO:0044278	cell wall disruption in other organism
0.42	GO:0048583	regulation of response to stimulus
0.41	GO:0050678	regulation of epithelial cell proliferation
0.41	GO:0045617	negative regulation of keratinocyte differentiation
0.40	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.40	GO:0010646	regulation of cell communication
0.40	GO:0023051	regulation of signaling
0.40	GO:0016126	sterol biosynthetic process
0.40	GO:0050830	defense response to Gram-positive bacterium

0.86	GO:2001065	mannan binding
0.77	GO:0008201	heparin binding
0.42	GO:0008083	growth factor activity
0.42	GO:0005509	calcium ion binding
0.41	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.40	GO:0070492	oligosaccharide binding
0.38	GO:0042834	peptidoglycan binding
0.37	GO:0019903	protein phosphatase binding
0.36	GO:0042803	protein homodimerization activity

0.47	GO:0005737	cytoplasm
0.46	GO:0005576	extracellular region
0.42	GO:0031982	vesicle
0.38	GO:0012505	endomembrane system
0.38	GO:0032809	neuronal cell body membrane
0.38	GO:0032590	dendrite membrane
0.38	GO:0045178	basal part of cell
0.37	GO:0030426	growth cone
0.36	GO:0044216	other organism cell
0.35	GO:0043229	intracellular organelle

0.41	EC:2.3.3.10	GO:0004421
0.41	KEGG:R01978	GO:0004421

tr|L7N0C5|L7N0C5_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.51	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0C6|L7N0C6_CANLF
Olfactory receptor
Search

0.42	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.60	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0C7|L7N0C7_CANLF
Uncharacterized protein
Search

0.38	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0C9|L7N0C9_CANLF
Uncharacterized protein
Search

0.93	T-cell surface glycoprotein CD1e, membrane-associated

0.61	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib
0.55	GO:0019884	antigen processing and presentation of exogenous antigen
0.49	GO:0019883	antigen processing and presentation of endogenous antigen
0.48	GO:0042102	positive regulation of T cell proliferation
0.44	GO:0006955	immune response
0.38	GO:0042110	T cell activation
0.37	GO:0006952	defense response
0.36	GO:0002252	immune effector process
0.35	GO:0034113	heterotypic cell-cell adhesion
0.35	GO:0016045	detection of bacterium

0.62	GO:0030884	exogenous lipid antigen binding
0.57	GO:0030883	endogenous lipid antigen binding
0.57	GO:0071723	lipopeptide binding
0.56	GO:0030881	beta-2-microglobulin binding
0.47	GO:0050839	cell adhesion molecule binding
0.46	GO:0042393	histone binding
0.38	GO:0051861	glycolipid binding

0.46	GO:0012505	endomembrane system
0.45	GO:0009986	cell surface
0.43	GO:0005764	lysosome
0.42	GO:0005886	plasma membrane
0.42	GO:0031410	cytoplasmic vesicle
0.42	GO:0044437	vacuolar part
0.42	GO:0098588	bounding membrane of organelle
0.41	GO:0098805	whole membrane
0.37	GO:0031984	organelle subcompartment
0.34	GO:0043233	organelle lumen

tr|L7N0D2|L7N0D2_CANLF
Uncharacterized protein
Search

0.84	Zinc finger with KRAB and SCAN domains 4 isoform 3

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.42	GO:0015074	DNA integration
0.41	GO:2000773	negative regulation of cellular senescence
0.40	GO:0007040	lysosome organization
0.38	GO:0010507	negative regulation of autophagy
0.38	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:1902679	negative regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0046872	metal ion binding
0.49	GO:0003676	nucleic acid binding
0.39	GO:0042802	identical protein binding
0.39	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.42	GO:0005829	cytosol
0.40	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0D4|L7N0D4_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0D5|L7N0D5_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0D7|L7N0D7_CANLF
Uncharacterized protein
Search

0.97	Interferon gamma-induced GTPase

0.53	GO:0035458	cellular response to interferon-beta
0.49	GO:0075071	autophagy involved in symbiotic interaction
0.49	GO:0060332	positive regulation of response to interferon-gamma
0.49	GO:1901098	positive regulation of autophagosome maturation
0.48	GO:0061762	CAMKK-AMPK signaling cascade
0.48	GO:0060334	regulation of interferon-gamma-mediated signaling pathway
0.48	GO:0061739	protein lipidation involved in autophagosome assembly
0.48	GO:0061635	regulation of protein complex stability
0.48	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.48	GO:0006952	defense response

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0051434	BH3 domain binding
0.48	GO:0050700	CARD domain binding
0.47	GO:0003924	GTPase activity
0.46	GO:0043539	protein serine/threonine kinase activator activity
0.44	GO:0019901	protein kinase binding

0.46	GO:0031984	organelle subcompartment
0.46	GO:0012505	endomembrane system
0.44	GO:0005829	cytosol
0.43	GO:0098588	bounding membrane of organelle
0.41	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0001891	phagocytic cup
0.40	GO:0045335	phagocytic vesicle
0.39	GO:0020003	symbiont-containing vacuole
0.39	GO:0030659	cytoplasmic vesicle membrane
0.38	GO:0098805	whole membrane

tr|L7N0D8|L7N0D8_CANLF
Uncharacterized protein
Search

LHX3

0.95	Lim homeobox protein 3 splice variant

0.70	GO:0021526	medial motor column neuron differentiation
0.67	GO:0021521	ventral spinal cord interneuron specification
0.65	GO:0008045	motor neuron axon guidance
0.63	GO:0021527	spinal cord association neuron differentiation
0.62	GO:0021520	spinal cord motor neuron cell fate specification
0.62	GO:0001890	placenta development
0.61	GO:0021983	pituitary gland development
0.60	GO:0043066	negative regulation of apoptotic process
0.59	GO:0048839	inner ear development
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II

0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0001085	RNA polymerase II transcription factor binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0046872	metal ion binding
0.53	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.54	GO:0005667	transcription factor complex

tr|L7N0D9|L7N0D9_CANLF
Histone H2A
Search

tr|L7N0E0|L7N0E0_CANLF
Uncharacterized protein
Search

DOCK1

0.83	Dedicator of cytokinesis protein 1

0.77	GO:0016477	cell migration
0.76	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.71	GO:0007010	cytoskeleton organization
0.56	GO:0002244	hematopoietic progenitor cell differentiation
0.41	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.41	GO:0010634	positive regulation of epithelial cell migration
0.39	GO:0006909	phagocytosis
0.38	GO:0006915	apoptotic process
0.37	GO:0002431	Fc receptor mediated stimulatory signaling pathway

0.76	GO:0005096	GTPase activator activity
0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.38	GO:0017124	SH3 domain binding
0.36	GO:0017048	Rho GTPase binding
0.34	GO:0020037	heme binding

0.54	GO:0016607	nuclear speck
0.49	GO:0005829	cytosol
0.41	GO:0032045	guanyl-nucleotide exchange factor complex
0.30	GO:0016020	membrane

tr|L7N0E1|L7N0E1_CANLF
Uncharacterized protein
Search

0.97	small integral membrane protein 10

0.48	GO:0032012	regulation of ARF protein signal transduction
0.42	GO:0065009	regulation of molecular function

0.48

GO:0005086

ARF guanyl-nucleotide exchange factor activity

0.30

GO:0044425

membrane part

tr|L7N0E3|L7N0E3_CANLF
Uncharacterized protein
Search

0.41	GO:0006968	cellular defense response
0.36	GO:0007165	signal transduction
0.35	GO:0050776	regulation of immune response

0.64	GO:0030246	carbohydrate binding
0.52	GO:0023024	MHC class I protein complex binding
0.37	GO:1990405	protein antigen binding
0.37	GO:0099600	transmembrane receptor activity
0.36	GO:0038023	signaling receptor activity

0.46	GO:0043235	receptor complex
0.43	GO:0009897	external side of plasma membrane
0.34	GO:0005887	integral component of plasma membrane

tr|L7N0E4|L7N0E4_CANLF
Olfactory receptor
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0E5|L7N0E5_CANLF
Uncharacterized protein
Search

0.87	Ig lambda chain V region 4A

0.85

GO:0003823

antigen binding

tr|L7N0E6|L7N0E6_CANLF
Uncharacterized protein
Search

0.92	Immunoglobulin lambda variable 1-40

0.83	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.81	GO:0038095	Fc-epsilon receptor signaling pathway
0.79	GO:0030449	regulation of complement activation
0.79	GO:0002250	adaptive immune response
0.76	GO:0002449	lymphocyte mediated immunity
0.76	GO:0006956	complement activation
0.75	GO:0050900	leukocyte migration
0.66	GO:0006898	receptor-mediated endocytosis
0.60	GO:0002377	immunoglobulin production
0.56	GO:0006508	proteolysis

0.82	GO:0003823	antigen binding
0.63	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005576	extracellular region
0.54	GO:0005886	plasma membrane
0.53	GO:0031982	vesicle

0.63

GO:0004252

tr|L7N0E7|L7N0E7_CANLF
Uncharacterized protein
Search

0.90	Immunoglobulin lambda variable 1-40

0.83	GO:0002250	adaptive immune response
0.83	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.82	GO:0038095	Fc-epsilon receptor signaling pathway
0.79	GO:0030449	regulation of complement activation
0.76	GO:0002449	lymphocyte mediated immunity
0.76	GO:0006956	complement activation
0.75	GO:0050900	leukocyte migration
0.66	GO:0006898	receptor-mediated endocytosis
0.60	GO:0002377	immunoglobulin production
0.56	GO:0006508	proteolysis

0.85	GO:0003823	antigen binding
0.63	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005576	extracellular region
0.56	GO:0005886	plasma membrane
0.52	GO:0031982	vesicle

0.63

GO:0004252

tr|L7N0E8|L7N0E8_CANLF
Uncharacterized protein
Search

0.96	Anti-staphylococcal enterotoxin D variable region lambda chain (Fragment)

0.85	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response

0.70

GO:0003823

antigen binding

0.73	GO:0005615	extracellular space
0.48	GO:0005886	plasma membrane

tr|L7N0E9|L7N0E9_CANLF
Ferritin
Search

FTH1

0.52	Ferritin heavy chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.54	GO:0051238	sequestering of metal ion
0.50	GO:0051651	maintenance of location in cell
0.42	GO:0042127	regulation of cell proliferation
0.41	GO:0055114	oxidation-reduction process
0.40	GO:0006955	immune response
0.39	GO:0048523	negative regulation of cellular process
0.36	GO:1904229	regulation of succinate dehydrogenase activity
0.36	GO:1904234	positive regulation of aconitate hydratase activity

0.76	GO:0008199	ferric iron binding
0.55	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.35	GO:0005515	protein binding

0.38	GO:0044754	autolysosome
0.37	GO:0005739	mitochondrion
0.35	GO:0031982	vesicle
0.35	GO:0043230	extracellular organelle
0.35	GO:0070288	ferritin complex
0.35	GO:0005615	extracellular space
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol

0.55

EC:1.16.3

GO:0016724

tr|L7N0F1|L7N0F1_CANLF
Uncharacterized protein
Search

IGLL1

0.96	Immunoglobulin lambda like polypeptide 1

0.83	GO:0002250	adaptive immune response
0.80	GO:0006910	phagocytosis, recognition
0.79	GO:0006911	phagocytosis, engulfment
0.79	GO:0050853	B cell receptor signaling pathway
0.78	GO:0050871	positive regulation of B cell activation
0.77	GO:0002449	lymphocyte mediated immunity
0.77	GO:0006956	complement activation
0.72	GO:0045087	innate immune response
0.71	GO:0042742	defense response to bacterium
0.62	GO:0050900	leukocyte migration

0.85	GO:0003823	antigen binding
0.80	GO:0034987	immunoglobulin receptor binding

0.80	GO:0042571	immunoglobulin complex, circulating
0.79	GO:0072562	blood microparticle
0.75	GO:0009897	external side of plasma membrane
0.74	GO:0070062	extracellular exosome

tr|L7N0F2|L7N0F2_CANLF
Uncharacterized protein
Search

0.81	Ig lambda chain C regions

0.85

GO:0003823

antigen binding

tr|L7N0F3|L7N0F3_CANLF
Uncharacterized protein
Search

0.10	melanoma antigen preferentially expressed in tumors

0.77	GO:0045596	negative regulation of cell differentiation
0.77	GO:0008284	positive regulation of cell proliferation
0.76	GO:0043066	negative regulation of apoptotic process
0.70	GO:0045892	negative regulation of transcription, DNA-templated
0.46	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.35	GO:0040008	regulation of growth
0.35	GO:0006915	apoptotic process
0.34	GO:0030154	cell differentiation
0.33	GO:0006351	transcription, DNA-templated

0.45

GO:0042974

retinoic acid receptor binding

0.35	GO:0001669	acrosomal vesicle
0.33	GO:0005634	nucleus
0.33	GO:0042995	cell projection
0.33	GO:0005886	plasma membrane

tr|L7N0F4|L7N0F4_CANLF
Uncharacterized protein
Search

0.91	Integrin subunit alpha D

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.61	GO:0043315	positive regulation of neutrophil degranulation
0.59	GO:0010668	ectodermal cell differentiation
0.59	GO:0032930	positive regulation of superoxide anion generation
0.53	GO:0050798	activated T cell proliferation
0.50	GO:2000361	regulation of prostaglandin-E synthase activity
0.50	GO:1903533	regulation of protein targeting
0.49	GO:0045963	negative regulation of dopamine metabolic process
0.49	GO:0090316	positive regulation of intracellular protein transport

0.53	GO:0031072	heat shock protein binding
0.49	GO:0001851	complement component C3b binding
0.46	GO:0043395	heparan sulfate proteoglycan binding
0.44	GO:0008201	heparin binding
0.43	GO:0046982	protein heterodimerization activity
0.38	GO:0046872	metal ion binding
0.35	GO:0004872	receptor activity
0.34	GO:0003735	structural constituent of ribosome

0.81	GO:0008305	integrin complex
0.57	GO:0009986	cell surface
0.56	GO:0044853	plasma membrane raft
0.51	GO:0005615	extracellular space
0.49	GO:0098552	side of membrane
0.44	GO:1903561	extracellular vesicle
0.41	GO:0070821	tertiary granule membrane
0.39	GO:0005634	nucleus
0.38	GO:0101003	ficolin-1-rich granule membrane
0.38	GO:0035579	specific granule membrane

tr|L7N0F5|L7N0F5_CANLF
Uncharacterized protein
Search

REG4

0.97	Regenerating islet-derived protein 4

0.42	GO:0008284	positive regulation of cell proliferation
0.42	GO:0016126	sterol biosynthetic process
0.42	GO:0048583	regulation of response to stimulus
0.42	GO:0044278	cell wall disruption in other organism
0.41	GO:0050678	regulation of epithelial cell proliferation
0.41	GO:0045617	negative regulation of keratinocyte differentiation
0.40	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.40	GO:0010646	regulation of cell communication
0.40	GO:0023051	regulation of signaling
0.40	GO:0008299	isoprenoid biosynthetic process

0.85	GO:2001065	mannan binding
0.76	GO:0008201	heparin binding
0.43	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.42	GO:0008083	growth factor activity
0.42	GO:0005509	calcium ion binding
0.40	GO:0070492	oligosaccharide binding
0.38	GO:0042834	peptidoglycan binding
0.37	GO:0019903	protein phosphatase binding
0.36	GO:0042803	protein homodimerization activity

0.47	GO:0005737	cytoplasm
0.46	GO:0005576	extracellular region
0.42	GO:0031982	vesicle
0.38	GO:0012505	endomembrane system
0.38	GO:0032809	neuronal cell body membrane
0.38	GO:0032590	dendrite membrane
0.38	GO:0045178	basal part of cell
0.37	GO:0030426	growth cone
0.36	GO:0044216	other organism cell
0.35	GO:0043229	intracellular organelle

0.43	EC:2.3.3.10	GO:0004421
0.43	KEGG:R01978	GO:0004421

tr|L7N0F6|L7N0F6_CANLF
Uncharacterized protein
Search

GPBAR1

0.97	G protein-coupled bile acid receptor

0.75	GO:0038183	bile acid signaling pathway
0.72	GO:2000810	regulation of bicellular tight junction assembly
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.44	GO:0030041	actin filament polymerization
0.43	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.36	GO:0007166	cell surface receptor signaling pathway

0.75	GO:0038181	bile acid receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.48	GO:0005886	plasma membrane
0.43	GO:0005737	cytoplasm
0.43	GO:0005885	Arp2/3 protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0F7|L7N0F7_CANLF
Uncharacterized protein
Search

tr|L7N0F9|L7N0F9_CANLF
Uncharacterized protein
Search

0.73	RB associated KRAB zinc finger

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding

0.48

GO:0005654

nucleoplasm

tr|L7N0G0|L7N0G0_CANLF
Uncharacterized protein
Search

0.86	GO:0040015	negative regulation of multicellular organism growth
0.86	GO:0060259	regulation of feeding behavior
0.85	GO:0046621	negative regulation of organ growth
0.85	GO:0046627	negative regulation of insulin receptor signaling pathway
0.85	GO:0045599	negative regulation of fat cell differentiation
0.85	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.83	GO:0019217	regulation of fatty acid metabolic process
0.81	GO:0042593	glucose homeostasis

0.54

GO:0005515

protein binding

0.83	GO:0005884	actin filament
0.78	GO:0005813	centrosome
0.59	GO:0005829	cytosol

tr|L7N0G1|L7N0G1_CANLF
Uncharacterized protein
Search

0.93	Small nuclear ribonucleoprotein-associated protein N

0.62	GO:0002377	immunoglobulin production
0.55	GO:0006955	immune response
0.46	GO:0043043	peptide biosynthetic process
0.44	GO:0044267	cellular protein metabolic process
0.43	GO:0010467	gene expression
0.42	GO:0009059	macromolecule biosynthetic process
0.39	GO:2001141	regulation of RNA biosynthetic process
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression

0.48

GO:0003735

structural constituent of ribosome

0.55	GO:0005615	extracellular space
0.54	GO:0030529	intracellular ribonucleoprotein complex
0.53	GO:0019013	viral nucleocapsid
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044444	cytoplasmic part

tr|L7N0G2|L7N0G2_CANLF
Uncharacterized protein
Search

0.96	Cytochrome P450, subfamily IIIA (Niphedipine oxidase), polypeptide 4

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0002933	lipid hydroxylation
0.48	GO:0008202	steroid metabolic process
0.48	GO:0009822	alkaloid catabolic process
0.44	GO:0070988	demethylation
0.43	GO:0042445	hormone metabolic process
0.42	GO:0016098	monoterpenoid metabolic process
0.41	GO:1901615	organic hydroxy compound metabolic process
0.41	GO:0042738	exogenous drug catabolic process
0.41	GO:0042362	fat-soluble vitamin biosynthetic process

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.53	GO:0008395	steroid hydroxylase activity
0.42	GO:0030343	vitamin D3 25-hydroxylase activity
0.42	GO:0034875	caffeine oxidase activity
0.42	GO:0070576	vitamin D 24-hydroxylase activity
0.40	GO:0005496	steroid binding
0.38	GO:0019899	enzyme binding
0.36	GO:0019825	oxygen binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

GO:0016712

tr|L7N0G3|L7N0G3_CANLF
Uncharacterized protein
Search

RDM1

0.97	RAD52 motif-containing protein 1

0.63	GO:0006310	DNA recombination
0.63	GO:0006281	DNA repair

0.57	GO:0003723	RNA binding
0.36	GO:0003677	DNA binding
0.35	GO:0005515	protein binding

0.54	GO:0005730	nucleolus
0.51	GO:0005829	cytosol
0.42	GO:0015030	Cajal body
0.42	GO:0016605	PML body

tr|L7N0G4|L7N0G4_CANLF
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.45	GO:0071353	cellular response to interleukin-4
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0002576	platelet degranulation
0.34	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0018410	C-terminal protein amino acid modification
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0030705	cytoskeleton-dependent intracellular transport
0.33	GO:0051301	cell division

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0019899	enzyme binding
0.42	GO:0003725	double-stranded RNA binding
0.32	GO:0046872	metal ion binding

0.73	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.43	GO:0043209	myelin sheath
0.39	GO:0070062	extracellular exosome
0.37	GO:0045121	membrane raft
0.34	GO:0030496	midbody

tr|L7N0G5|L7N0G5_CANLF
Uncharacterized protein
Search

0.93	Immunoglobulin kappa variable 2-29

0.70	GO:0002377	immunoglobulin production
0.69	GO:0006955	immune response
0.64	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.63	GO:0038095	Fc-epsilon receptor signaling pathway
0.62	GO:0030449	regulation of complement activation
0.60	GO:0002449	lymphocyte mediated immunity
0.60	GO:0072376	protein activation cascade
0.59	GO:0050900	leukocyte migration
0.53	GO:0006898	receptor-mediated endocytosis
0.47	GO:0006508	proteolysis

0.78	GO:0003823	antigen binding
0.52	GO:0004252	serine-type endopeptidase activity

0.65	GO:0005615	extracellular space
0.50	GO:1903561	extracellular vesicle
0.49	GO:0005886	plasma membrane

0.52

GO:0004252

tr|L7N0G6|L7N0G6_CANLF
Uncharacterized protein
Search

0.97	Small integral membrane protein 10

0.43	GO:0032012	regulation of ARF protein signal transduction
0.39	GO:0065009	regulation of molecular function

0.43

GO:0005086

ARF guanyl-nucleotide exchange factor activity

0.30

GO:0044425

membrane part

tr|L7N0G7|L7N0G7_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0G8|L7N0G8_CANLF
Uncharacterized protein
Search

0.94	Keratin 36

0.62	GO:0045616	regulation of keratinocyte differentiation
0.42	GO:0042633	hair cycle
0.41	GO:0007568	aging

0.64

GO:0030280

structural constituent of epidermis

0.79	GO:0005882	intermediate filament
0.40	GO:0070062	extracellular exosome

tr|L7N0G9|L7N0G9_CANLF
Uncharacterized protein
Search

0.92	Keratin 32

0.54

GO:0045616

regulation of keratinocyte differentiation

0.62

GO:0005198

structural molecule activity

0.79	GO:0005882	intermediate filament
0.43	GO:0070062	extracellular exosome

tr|L7N0H0|L7N0H0_CANLF
Uncharacterized protein
Search

0.96	Type I wool keratin intermediate filament 8c1

0.42	GO:0042633	hair cycle
0.41	GO:0007568	aging
0.40	GO:0070268	cornification
0.39	GO:0045616	regulation of keratinocyte differentiation
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0009653	anatomical structure morphogenesis

0.62	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding

0.79	GO:0005882	intermediate filament
0.39	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol

tr|L7N0H2|L7N0H2_CANLF
Uncharacterized protein
Search

FHAD1

0.73	Forkhead-associated phosphopeptide-binding domain 1

0.61

GO:0005509

calcium ion binding

0.30

GO:0031224

intrinsic component of membrane

tr|L7N0H6|L7N0H6_CANLF
Uncharacterized protein
Search

RPL23A

0.82	Ribosomal protein L23a

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.51	GO:0000027	ribosomal large subunit assembly
0.41	GO:0008283	cell proliferation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0003723	RNA binding
0.42	GO:0045296	cadherin binding

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.43	GO:0031932	TORC2 complex
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0H7|L7N0H7_CANLF
Glyceraldehyde-3-phosphate dehydrogenase
Search

GAPDH

0.53	Glyceraldehyde-3-phosphate dehydrogenase

0.66	GO:0006006	glucose metabolic process
0.65	GO:0006757	ATP generation from ADP
0.64	GO:0006090	pyruvate metabolic process
0.63	GO:0016052	carbohydrate catabolic process
0.62	GO:0019362	pyridine nucleotide metabolic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.48	GO:0051402	neuron apoptotic process
0.46	GO:0051873	killing by host of symbiont cells
0.46	GO:0050821	protein stabilization

0.76	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.65	GO:0050661	NADP binding
0.63	GO:0051287	NAD binding
0.52	GO:0035605	peptidyl-cysteine S-nitrosylase activity
0.47	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.46	GO:0097718	disordered domain specific binding
0.44	GO:0008017	microtubule binding
0.42	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding

0.53	GO:0097452	GAIT complex
0.45	GO:0005829	cytosol
0.44	GO:0005811	lipid droplet
0.43	GO:0031965	nuclear membrane
0.43	GO:0015630	microtubule cytoskeleton
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome

0.76

EC:1.2.1.12

GO:0004365

tr|L7N0H8|L7N0H8_CANLF
Uncharacterized protein
Search

RPS24

0.69	40S ribosomal protein S24

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.45	GO:0042274	ribosomal small subunit biogenesis
0.43	GO:0016072	rRNA metabolic process
0.42	GO:0034101	erythrocyte homeostasis
0.35	GO:0048513	animal organ development
0.34	GO:0061008	hepaticobiliary system development
0.34	GO:0031099	regeneration

0.63	GO:0003735	structural constituent of ribosome
0.36	GO:0031369	translation initiation factor binding
0.34	GO:0032403	protein complex binding
0.33	GO:0003743	translation initiation factor activity

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

tr|L7N0H9|L7N0H9_CANLF
Uncharacterized protein
Search

0.96	Brain expressed X-linked 1

0.64	GO:0051091	positive regulation of DNA binding transcription factor activity
0.60	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0042981	regulation of apoptotic process
0.53	GO:0051726	regulation of cell cycle
0.43	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors

0.67	GO:0001102	RNA polymerase II activating transcription factor binding
0.54	GO:0042802	identical protein binding
0.44	GO:0005123	death receptor binding

0.60	GO:0005667	transcription factor complex
0.51	GO:0005829	cytosol

tr|L7N0I0|L7N0I0_CANLF
Uncharacterized protein
Search

0.58	Ig heavy chain V-III region GAL

0.84	GO:0006958	complement activation, classical pathway
0.83	GO:0006910	phagocytosis, recognition
0.82	GO:0006911	phagocytosis, engulfment
0.82	GO:0050853	B cell receptor signaling pathway
0.81	GO:0050871	positive regulation of B cell activation
0.75	GO:0045087	innate immune response
0.74	GO:0042742	defense response to bacterium
0.47	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.46	GO:0038095	Fc-epsilon receptor signaling pathway
0.46	GO:0030449	regulation of complement activation

0.85	GO:0003823	antigen binding
0.84	GO:0034987	immunoglobulin receptor binding
0.41	GO:0004252	serine-type endopeptidase activity

0.83	GO:0042571	immunoglobulin complex, circulating
0.83	GO:0072562	blood microparticle
0.78	GO:0009897	external side of plasma membrane
0.38	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.41

GO:0004252

tr|L7N0I1|L7N0I1_CANLF
Uncharacterized protein
Search

MYL12B

0.89	Myosin regulatory light chain

0.49	GO:0008360	regulation of cell shape
0.46	GO:0072659	protein localization to plasma membrane
0.36	GO:0070527	platelet aggregation
0.36	GO:0006936	muscle contraction
0.34	GO:0048013	ephrin receptor signaling pathway
0.34	GO:0031032	actomyosin structure organization

0.70	GO:0005509	calcium ion binding
0.53	GO:0032036	myosin heavy chain binding
0.48	GO:0035254	glutamate receptor binding
0.35	GO:0030898	actin-dependent ATPase activity
0.34	GO:0051015	actin filament binding
0.34	GO:0051020	GTPase binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0016460	myosin II complex
0.57	GO:0097517	contractile actin filament bundle
0.57	GO:0042641	actomyosin
0.56	GO:0030018	Z disc
0.50	GO:0005903	brush border
0.50	GO:0099738	cell cortex region
0.49	GO:0045177	apical part of cell
0.37	GO:0070062	extracellular exosome
0.35	GO:0097513	myosin II filament
0.34	GO:0005829	cytosol

tr|L7N0I2|L7N0I2_CANLF
Uncharacterized protein
Search

0.63	Lewis alpha-3-fucosyltransferase

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.43	GO:0006672	ceramide metabolic process
0.39	GO:0042355	L-fucose catabolic process
0.37	GO:0009312	oligosaccharide biosynthetic process
0.35	GO:0009988	cell-cell recognition
0.35	GO:0002522	leukocyte migration involved in immune response
0.34	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.33	GO:0031047	gene silencing by RNA

0.81	GO:0008417	fucosyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.81	GO:0032580	Golgi cisterna membrane
0.43	GO:0009986	cell surface
0.37	GO:0071944	cell periphery
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

tr|L7N0I4|L7N0I4_CANLF
Uncharacterized protein
Search

ATP5I

0.80	Mitochondrial ATP synthase subunit e

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0042407	cristae formation
0.37	GO:0006839	mitochondrial transport
0.37	GO:0001666	response to hypoxia
0.36	GO:0046907	intracellular transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.50	GO:0016887	ATPase activity
0.39	GO:0033142	progesterone receptor binding
0.39	GO:0047624	adenosine-tetraphosphatase activity
0.38	GO:0031490	chromatin DNA binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.36	GO:0000790	nuclear chromatin
0.36	GO:0032993	protein-DNA complex
0.30	GO:0016021	integral component of membrane

0.50

GO:0016887

tr|L7N0I5|L7N0I5_CANLF
Uncharacterized protein
Search

0.89	Melanoma-associated antigen 8

0.61	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0045746	negative regulation of Notch signaling pathway
0.41	GO:0033234	negative regulation of protein sumoylation
0.41	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.41	GO:0090398	cellular senescence
0.41	GO:1901984	negative regulation of protein acetylation
0.41	GO:0010955	negative regulation of protein processing
0.41	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.40	GO:0072331	signal transduction by p53 class mediator
0.40	GO:0051443	positive regulation of ubiquitin-protein transferase activity

0.65	GO:0042826	histone deacetylase binding
0.42	GO:0089720	caspase binding
0.41	GO:0070491	repressing transcription factor binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0008528	G-protein coupled peptide receptor activity

0.50	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005783	endoplasmic reticulum
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|L7N0I6|L7N0I6_CANLF
Claudin
Search

0.69

Claudin

0.60	GO:0045216	cell-cell junction organization
0.52	GO:0070293	renal absorption
0.51	GO:0061436	establishment of skin barrier
0.51	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.49	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.49	GO:0044409	entry into host
0.48	GO:0019058	viral life cycle
0.47	GO:1902476	chloride transmembrane transport
0.45	GO:0003382	epithelial cell morphogenesis
0.44	GO:0051291	protein heterooligomerization

0.62	GO:0005198	structural molecule activity
0.60	GO:0104005	hijacked molecular function
0.48	GO:0005254	chloride channel activity
0.45	GO:0042802	identical protein binding
0.34	GO:0004888	transmembrane signaling receptor activity
0.31	GO:0016787	hydrolase activity

0.81	GO:0005923	bicellular tight junction
0.64	GO:0016327	apicolateral plasma membrane
0.47	GO:0016328	lateral plasma membrane
0.43	GO:0005887	integral component of plasma membrane
0.39	GO:0043227	membrane-bounded organelle
0.39	GO:0009925	basal plasma membrane
0.38	GO:0043229	intracellular organelle
0.38	GO:0016324	apical plasma membrane
0.37	GO:0034707	chloride channel complex
0.34	GO:0043230	extracellular organelle

0.31

GO:0016787

tr|L7N0I7|L7N0I7_CANLF
Tubulin beta chain
Search

TUBB4B

0.50	Tubulin beta chain

0.71	GO:0007017	microtubule-based process
0.70	GO:0007010	cytoskeleton organization
0.47	GO:0031115	negative regulation of microtubule polymerization
0.39	GO:0060271	cilium assembly
0.36	GO:0000086	G2/M transition of mitotic cell cycle
0.36	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.36	GO:0140056	organelle localization by membrane tethering
0.35	GO:0006955	immune response
0.35	GO:0001909	leukocyte mediated cytotoxicity
0.35	GO:0002446	neutrophil mediated immunity

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003725	double-stranded RNA binding
0.41	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding

0.73	GO:0005874	microtubule
0.53	GO:0043209	myelin sheath
0.48	GO:0033269	internode region of axon
0.46	GO:0005737	cytoplasm
0.45	GO:0043025	neuronal cell body
0.44	GO:0044441	ciliary part
0.38	GO:0070062	extracellular exosome
0.36	GO:0031012	extracellular matrix
0.35	GO:0005634	nucleus
0.35	GO:0045298	tubulin complex

tr|L7N0I9|L7N0I9_CANLF
D-3-phosphoglycerate dehydrogenase
Search

PHGDH

0.53	Phosphoglycerate dehydrogenase

0.71	GO:0006564	L-serine biosynthetic process
0.57	GO:0070314	G1 to G0 transition
0.55	GO:0019530	taurine metabolic process
0.54	GO:0021510	spinal cord development
0.54	GO:0021782	glial cell development
0.53	GO:0021915	neural tube development
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0009448	gamma-aminobutyric acid metabolic process
0.51	GO:0031175	neuron projection development
0.49	GO:0006566	threonine metabolic process

0.73	GO:0004617	phosphoglycerate dehydrogenase activity
0.67	GO:0051287	NAD binding
0.41	GO:0030060	L-malate dehydrogenase activity
0.33	GO:0000287	magnesium ion binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0046983	protein dimerization activity

0.53	GO:0043209	myelin sheath
0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.32	GO:0005634	nucleus

0.73

EC:1.1.1.95

GO:0004617

tr|L7N0J0|L7N0J0_CANLF
Uncharacterized protein
Search

0.92	Immunoglobulin lambda variable 1-40

0.83	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.81	GO:0038095	Fc-epsilon receptor signaling pathway
0.79	GO:0002250	adaptive immune response
0.79	GO:0030449	regulation of complement activation
0.76	GO:0002449	lymphocyte mediated immunity
0.76	GO:0006956	complement activation
0.75	GO:0050900	leukocyte migration
0.66	GO:0006898	receptor-mediated endocytosis
0.60	GO:0002377	immunoglobulin production
0.56	GO:0006508	proteolysis

0.82	GO:0003823	antigen binding
0.63	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005576	extracellular region
0.54	GO:0005886	plasma membrane
0.52	GO:0031982	vesicle

0.63

GO:0004252

tr|L7N0J1|L7N0J1_CANLF
Uncharacterized protein
Search

0.92	Pregnancy-associated glycoprotein 7 (Fragment)

0.61	GO:0006508	proteolysis
0.49	GO:0002803	positive regulation of antibacterial peptide production
0.49	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.42	GO:0007586	digestion
0.34	GO:0051604	protein maturation
0.33	GO:0007565	female pregnancy
0.33	GO:0006629	lipid metabolic process
0.33	GO:0044265	cellular macromolecule catabolic process
0.32	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.44	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.32

GO:0016705

tr|L7N0J2|L7N0J2_CANLF
Uncharacterized protein
Search

0.86	Immunoglobulin lambda variable 2-8

0.80	GO:0002250	adaptive immune response
0.70	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.70	GO:0002377	immunoglobulin production
0.69	GO:0038095	Fc-epsilon receptor signaling pathway
0.68	GO:0030449	regulation of complement activation
0.65	GO:0002449	lymphocyte mediated immunity
0.65	GO:0006956	complement activation
0.65	GO:0050900	leukocyte migration
0.57	GO:0006898	receptor-mediated endocytosis
0.50	GO:0006508	proteolysis

0.83	GO:0003823	antigen binding
0.55	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005576	extracellular region
0.54	GO:0005886	plasma membrane
0.49	GO:0031982	vesicle

0.55

GO:0004252

tr|L7N0J3|L7N0J3_CANLF
Uncharacterized protein
Search

0.64	Ankyrin repeat domain-containing protein 26 (Fragment)

0.64	GO:0045599	negative regulation of fat cell differentiation
0.59	GO:0040015	negative regulation of multicellular organism growth
0.58	GO:0060259	regulation of feeding behavior
0.58	GO:0046621	negative regulation of organ growth
0.58	GO:0046627	negative regulation of insulin receptor signaling pathway
0.57	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.55	GO:0019217	regulation of fatty acid metabolic process
0.55	GO:0042593	glucose homeostasis

0.46

GO:0005515

protein binding

0.75	GO:0005813	centrosome
0.56	GO:0005884	actin filament
0.43	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0J4|L7N0J4_CANLF
Histone H2A
Search

0.65	GO:0006342	chromatin silencing
0.63	GO:0099643	signal release from synapse
0.63	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.59	GO:0006836	neurotransmitter transport
0.56	GO:0001505	regulation of neurotransmitter levels
0.54	GO:0051649	establishment of localization in cell
0.38	GO:0007018	microtubule-based movement

0.61	GO:0046982	protein heterodimerization activity
0.47	GO:0003677	DNA binding
0.42	GO:0030554	adenyl nucleotide binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003777	microtubule motor activity
0.38	GO:0008017	microtubule binding
0.34	GO:0016740	transferase activity

0.62	GO:0008021	synaptic vesicle
0.62	GO:0000790	nuclear chromatin
0.61	GO:0000786	nucleosome
0.50	GO:0099501	exocytic vesicle membrane
0.49	GO:0014069	postsynaptic density
0.38	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016740

tr|L7N0J5|L7N0J5_CANLF
Uncharacterized protein
Search

0.86	Immunoglobulin lambda variable 8-61

0.80	GO:0002377	immunoglobulin production
0.77	GO:0002250	adaptive immune response
0.58	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.57	GO:0038095	Fc-epsilon receptor signaling pathway
0.56	GO:0030449	regulation of complement activation
0.54	GO:0002449	lymphocyte mediated immunity
0.54	GO:0006956	complement activation
0.54	GO:0050900	leukocyte migration
0.49	GO:0006898	receptor-mediated endocytosis
0.44	GO:0006508	proteolysis

0.80	GO:0003823	antigen binding
0.48	GO:0004252	serine-type endopeptidase activity

0.69	GO:0005615	extracellular space
0.53	GO:0005886	plasma membrane

0.48

GO:0004252

tr|L7N0J6|L7N0J6_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0031492	nucleosomal DNA binding
0.33	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.33	GO:0000785	chromatin
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0J8|L7N0J8_CANLF
Uncharacterized protein
Search

MUM1

0.89	PWWP domain-containing protein MUM1L1

0.60	GO:0006325	chromatin organization
0.55	GO:0006281	DNA repair

0.68

GO:0031491

nucleosome binding

0.52	GO:0005634	nucleus
0.45	GO:0070062	extracellular exosome

tr|L7N0J9|L7N0J9_CANLF
Uncharacterized protein
Search

0.40	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0K0|L7N0K0_CANLF
Olfactory receptor
Search

0.43	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0K1|L7N0K1_CANLF
Uncharacterized protein
Search

0.93	Immunoglobulin lambda variable 1-40

0.78	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.77	GO:0002250	adaptive immune response
0.77	GO:0038095	Fc-epsilon receptor signaling pathway
0.75	GO:0030449	regulation of complement activation
0.72	GO:0002449	lymphocyte mediated immunity
0.72	GO:0006956	complement activation
0.71	GO:0050900	leukocyte migration
0.66	GO:0002377	immunoglobulin production
0.63	GO:0006898	receptor-mediated endocytosis
0.54	GO:0006508	proteolysis

0.80	GO:0003823	antigen binding
0.60	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005576	extracellular region
0.53	GO:0005886	plasma membrane
0.49	GO:0031982	vesicle

0.60

GO:0004252

tr|L7N0K2|L7N0K2_CANLF
Uncharacterized protein
Search

0.69	Immunoglobulin heavy variable 3-7

0.85	GO:0006958	complement activation, classical pathway
0.84	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.84	GO:0006909	phagocytosis
0.73	GO:0099024	plasma membrane invagination
0.72	GO:0050871	positive regulation of B cell activation
0.70	GO:0038094	Fc-gamma receptor signaling pathway
0.70	GO:0038095	Fc-epsilon receptor signaling pathway
0.68	GO:0008037	cell recognition
0.68	GO:0030449	regulation of complement activation
0.67	GO:0045087	innate immune response

0.85	GO:0003823	antigen binding
0.74	GO:0034987	immunoglobulin receptor binding
0.56	GO:0004252	serine-type endopeptidase activity

0.78	GO:0072562	blood microparticle
0.74	GO:0042571	immunoglobulin complex, circulating
0.69	GO:0009897	external side of plasma membrane
0.50	GO:0070062	extracellular exosome

0.56

GO:0004252

tr|L7N0K3|L7N0K3_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0K4|L7N0K4_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0015671	oxygen transport

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005344	oxygen carrier activity
0.33	GO:0019825	oxygen binding
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.55	GO:0005886	plasma membrane
0.33	GO:0005833	hemoglobin complex
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0K5|L7N0K5_CANLF
Elongation factor 1-alpha
Search

EEF1A1

0.35	Eukaryotic translation elongation factor 1 alpha 1

0.67	GO:0006414	translational elongation
0.48	GO:0071364	cellular response to epidermal growth factor stimulus
0.34	GO:1904714	regulation of chaperone-mediated autophagy
0.34	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.34	GO:0043312	neutrophil degranulation
0.34	GO:1990090	cellular response to nerve growth factor stimulus
0.34	GO:0010976	positive regulation of neuron projection development
0.34	GO:0035690	cellular response to drug
0.34	GO:0007568	aging
0.33	GO:0010942	positive regulation of cell death

0.68	GO:0003746	translation elongation factor activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.65	GO:0003924	GTPase activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005516	calmodulin binding
0.44	GO:0019901	protein kinase binding
0.41	GO:0000049	tRNA binding
0.33	GO:0003729	mRNA binding

0.46	GO:0032587	ruffle membrane
0.46	GO:0043209	myelin sheath
0.45	GO:0005737	cytoplasm
0.43	GO:0005730	nucleolus
0.43	GO:0015629	actin cytoskeleton
0.42	GO:0044430	cytoskeletal part
0.36	GO:0070062	extracellular exosome
0.34	GO:0031983	vesicle lumen
0.33	GO:0098562	cytoplasmic side of membrane
0.33	GO:0097708	intracellular vesicle

tr|L7N0K6|L7N0K6_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.69	GO:0007186	G-protein coupled receptor signaling pathway

0.74	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0K7|L7N0K7_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0K8|L7N0K8_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0K9|L7N0K9_CANLF
Uncharacterized protein
Search

RPL37

0.72	Ribosomal protein L37

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.63	GO:0019843	rRNA binding
0.62	GO:0003735	structural constituent of ribosome
0.52	GO:0046872	metal ion binding
0.34	GO:0019838	growth factor binding

0.60	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0L1|L7N0L1_CANLF
Uncharacterized protein
Search

0.39	Seven transmembrane helix receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0007210	serotonin receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity
0.50	GO:0099589	serotonin receptor activity
0.46	GO:0030594	neurotransmitter receptor activity
0.38	GO:0005549	odorant binding

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0L2|L7N0L2_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0006596	polyamine biosynthetic process

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.32	GO:0016740	transferase activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

tr|L7N0L3|L7N0L3_CANLF
Histone H4
Search

tr|L7N0L4|L7N0L4_CANLF
Uncharacterized protein
Search

0.70	Immunoglobulin heavy constant mu

0.85	GO:0006958	complement activation, classical pathway
0.84	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.84	GO:0006909	phagocytosis
0.75	GO:0099024	plasma membrane invagination
0.74	GO:0050871	positive regulation of B cell activation
0.70	GO:0008037	cell recognition
0.69	GO:0045087	innate immune response
0.68	GO:0042742	defense response to bacterium
0.67	GO:0038094	Fc-gamma receptor signaling pathway
0.67	GO:0038095	Fc-epsilon receptor signaling pathway

0.85	GO:0003823	antigen binding
0.77	GO:0034987	immunoglobulin receptor binding
0.54	GO:0004252	serine-type endopeptidase activity

0.79	GO:0072562	blood microparticle
0.76	GO:0042571	immunoglobulin complex, circulating
0.71	GO:0009897	external side of plasma membrane
0.48	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.54

GO:0004252

tr|L7N0L5|L7N0L5_CANLF
Histone H2B
Search

0.92	Histone H2B type 3-B

0.53	GO:0006334	nucleosome assembly
0.38	GO:0002227	innate immune response in mucosa
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.36	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0031640	killing of cells of other organism
0.35	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.35	GO:0097677	STAT family protein binding
0.34	GO:0001530	lipopolysaccharide binding
0.34	GO:0044389	ubiquitin-like protein ligase binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.36	GO:0005615	extracellular space
0.33	GO:1903561	extracellular vesicle
0.33	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane

tr|L7N0L6|L7N0L6_CANLF
Uncharacterized protein
Search

tr|L7N0L7|L7N0L7_CANLF
Uncharacterized protein
Search

USP6NL

0.71	USP6 N-terminal like

0.81	GO:0031338	regulation of vesicle fusion
0.81	GO:0090630	activation of GTPase activity
0.67	GO:0006886	intracellular protein transport
0.48	GO:0035526	retrograde transport, plasma membrane to Golgi
0.47	GO:0048227	plasma membrane to endosome transport
0.47	GO:1903358	regulation of Golgi organization
0.45	GO:0007030	Golgi organization
0.42	GO:0019068	virion assembly

0.78	GO:0017137	Rab GTPase binding
0.74	GO:0005096	GTPase activator activity
0.36	GO:0003723	RNA binding

0.65	GO:0012505	endomembrane system
0.44	GO:0005622	intracellular
0.42	GO:0031982	vesicle
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|L7N0L8|L7N0L8_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0008270	zinc ion binding

0.55	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0L9|L7N0L9_CANLF
Uncharacterized protein
Search

0.55	Creatine kinase B-type

0.56	GO:0016310	phosphorylation
0.41	GO:0030644	cellular chloride ion homeostasis
0.39	GO:0007420	brain development
0.38	GO:0032091	negative regulation of protein binding
0.37	GO:0043066	negative regulation of apoptotic process
0.36	GO:0006600	creatine metabolic process
0.36	GO:0048857	neural nucleus development
0.33	GO:0006754	ATP biosynthetic process

0.59	GO:0016301	kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor

0.49	GO:0043209	myelin sheath
0.46	GO:0005615	extracellular space
0.43	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.37	GO:0043230	extracellular organelle
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.35	GO:0031982	vesicle
0.34	GO:0005634	nucleus
0.34	GO:0019866	organelle inner membrane

0.45

EC:2.7.3

GO:0016775

tr|L7N0M0|L7N0M0_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0M1|L7N0M1_CANLF
Uncharacterized protein
Search

0.61	GO:0045599	negative regulation of fat cell differentiation
0.56	GO:0040015	negative regulation of multicellular organism growth
0.55	GO:0060259	regulation of feeding behavior
0.55	GO:0046621	negative regulation of organ growth
0.55	GO:0046627	negative regulation of insulin receptor signaling pathway
0.54	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:0019217	regulation of fatty acid metabolic process
0.52	GO:0042593	glucose homeostasis

0.44

GO:0005515

protein binding

0.67	GO:0005813	centrosome
0.53	GO:0005884	actin filament
0.41	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0M2|L7N0M2_CANLF
UDP-glucuronosyltransferase
Search

0.54	UDP-glucuronosyltransferase

0.49	GO:0052695	cellular glucuronidation
0.40	GO:0008202	steroid metabolic process
0.38	GO:0006805	xenobiotic metabolic process
0.37	GO:0034754	cellular hormone metabolic process
0.37	GO:0018879	biphenyl metabolic process
0.37	GO:0071394	cellular response to testosterone stimulus
0.36	GO:0071361	cellular response to ethanol
0.36	GO:0071378	cellular response to growth hormone stimulus
0.36	GO:0071385	cellular response to glucocorticoid stimulus
0.36	GO:0032496	response to lipopolysaccharide

0.80	GO:0015020	glucuronosyltransferase activity
0.40	GO:0001972	retinoic acid binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0005635	nuclear envelope
0.33	GO:0098805	whole membrane
0.33	GO:0019867	outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.4.1.17

GO:0015020

tr|L7N0M3|L7N0M3_CANLF
UDP-glucuronosyltransferase
Search

0.54	UDP-glucuronosyltransferase

0.49	GO:0052695	cellular glucuronidation
0.40	GO:0008202	steroid metabolic process
0.38	GO:0006805	xenobiotic metabolic process
0.37	GO:0034754	cellular hormone metabolic process
0.37	GO:0018879	biphenyl metabolic process
0.37	GO:0071394	cellular response to testosterone stimulus
0.36	GO:0071361	cellular response to ethanol
0.36	GO:0071378	cellular response to growth hormone stimulus
0.36	GO:0071385	cellular response to glucocorticoid stimulus
0.36	GO:0032496	response to lipopolysaccharide

0.81	GO:0015020	glucuronosyltransferase activity
0.40	GO:0001972	retinoic acid binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0005635	nuclear envelope
0.33	GO:0098805	whole membrane
0.33	GO:0019867	outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.4.1.17

GO:0015020

tr|L7N0M6|L7N0M6_CANLF
Uncharacterized protein
Search

EEF1A1

0.43	Translation elongation factor EF-1 subunit alpha

0.68	GO:0006414	translational elongation
0.51	GO:0071364	cellular response to epidermal growth factor stimulus
0.35	GO:1904714	regulation of chaperone-mediated autophagy
0.35	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.35	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0010976	positive regulation of neuron projection development
0.34	GO:0035690	cellular response to drug
0.34	GO:0007568	aging
0.34	GO:0010942	positive regulation of cell death

0.69	GO:0003746	translation elongation factor activity
0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0005516	calmodulin binding
0.43	GO:0000049	tRNA binding
0.34	GO:0003729	mRNA binding

0.49	GO:0032587	ruffle membrane
0.47	GO:0005737	cytoplasm
0.47	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.45	GO:0015629	actin cytoskeleton
0.43	GO:0044430	cytoskeletal part
0.37	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0097708	intracellular vesicle

tr|L7N0M7|L7N0M7_CANLF
Histone H2B
Search

tr|L7N0M8|L7N0M8_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0M9|L7N0M9_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.51	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0N0|L7N0N0_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0N1|L7N0N1_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0N2|L7N0N2_CANLF
Uncharacterized protein
Search

0.91	Tumor antigen MAGE-N

0.59	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0045746	negative regulation of Notch signaling pathway
0.53	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.48	GO:0044257	cellular protein catabolic process
0.35	GO:0006351	transcription, DNA-templated

0.63	GO:0042826	histone deacetylase binding
0.51	GO:0031625	ubiquitin protein ligase binding

0.56	GO:0005829	cytosol
0.56	GO:0031981	nuclear lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0005886	plasma membrane

tr|L7N0N3|L7N0N3_CANLF
Uncharacterized protein
Search

0.91	Melanoma-associated antigen 8

0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.53	GO:0045746	negative regulation of Notch signaling pathway
0.48	GO:0044257	cellular protein catabolic process
0.35	GO:0006351	transcription, DNA-templated

0.62	GO:0042826	histone deacetylase binding
0.51	GO:0031625	ubiquitin protein ligase binding

0.57	GO:0005829	cytosol
0.57	GO:0031981	nuclear lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0005886	plasma membrane

tr|L7N0N4|L7N0N4_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.47	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0N5|L7N0N5_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0N6|L7N0N6_CANLF
Alpha-amylase
Search

0.43	Pancreatic alpha-amylase

0.60	GO:0005975	carbohydrate metabolic process
0.37	GO:0007586	digestion
0.36	GO:1901575	organic substance catabolic process

0.81	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.80	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding
0.41	GO:0031404	chloride ion binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.41	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.2.1.1

GO:0004556

tr|L7N0N7|L7N0N7_CANLF
Olfactory receptor
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0N9|L7N0N9_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0P1|L7N0P1_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.35	GO:0090543	Flemming body
0.34	GO:0097431	mitotic spindle pole
0.34	GO:0032154	cleavage furrow
0.34	GO:1990023	mitotic spindle midzone
0.34	GO:0055037	recycling endosome
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0P2|L7N0P2_CANLF
Uncharacterized protein
Search

RPL31

0.67	Ribosomal protein L31

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0006298	mismatch repair
0.34	GO:0042254	ribosome biogenesis

0.63	GO:0003735	structural constituent of ribosome
0.35	GO:0003796	lysozyme activity
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0004519	endonuclease activity

0.60	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.43	GO:0005844	polysome
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098588	bounding membrane of organelle

0.35

GO:0003796

tr|L7N0P4|L7N0P4_CANLF
Uncharacterized protein
Search

0.96	Keratin, type II cytoskeletal 74

0.57	GO:0045104	intermediate filament cytoskeleton organization
0.51	GO:0031069	hair follicle morphogenesis
0.46	GO:0097435	supramolecular fiber organization
0.40	GO:0031424	keratinization
0.38	GO:0012501	programmed cell death
0.35	GO:0032980	keratinocyte activation
0.34	GO:0051546	keratinocyte migration
0.34	GO:0043616	keratinocyte proliferation
0.34	GO:0003334	keratinocyte development
0.34	GO:0050680	negative regulation of epithelial cell proliferation

0.62	GO:0005198	structural molecule activity
0.50	GO:1990254	keratin filament binding
0.33	GO:0008092	cytoskeletal protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.34	GO:0001533	cornified envelope
0.34	GO:0005634	nucleus
0.33	GO:0009986	cell surface

tr|L7N0P5|L7N0P5_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.51	GO:0005549	odorant binding

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0P7|L7N0P7_CANLF
Uncharacterized protein
Search

0.97	Olfactory receptor family 56 subfamily A member 5

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.54	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.53	GO:0001963	synaptic transmission, dopaminergic
0.53	GO:0048148	behavioral response to cocaine
0.52	GO:0014059	regulation of dopamine secretion
0.52	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.52	GO:0007194	negative regulation of adenylate cyclase activity
0.52	GO:0048149	behavioral response to ethanol

0.76	GO:0004984	olfactory receptor activity
0.67	GO:0004930	G-protein coupled receptor activity
0.53	GO:0035240	dopamine binding
0.48	GO:0030594	neurotransmitter receptor activity

0.53	GO:0005886	plasma membrane
0.51	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

tr|L7N0P8|L7N0P8_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.53	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0P9|L7N0P9_CANLF
Uncharacterized protein
Search

0.96	Immunoglobulin kappa variable 2-30

0.71	GO:0002250	adaptive immune response
0.69	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.69	GO:0002377	immunoglobulin production
0.68	GO:0038095	Fc-epsilon receptor signaling pathway
0.66	GO:0030449	regulation of complement activation
0.64	GO:0002449	lymphocyte mediated immunity
0.64	GO:0006956	complement activation
0.64	GO:0050900	leukocyte migration
0.57	GO:0006898	receptor-mediated endocytosis
0.49	GO:0006508	proteolysis

0.80	GO:0003823	antigen binding
0.55	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005615	extracellular space
0.53	GO:1903561	extracellular vesicle
0.50	GO:0005886	plasma membrane

0.55

GO:0004252

tr|L7N0Q0|L7N0Q0_CANLF
Olfactory receptor
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0Q1|L7N0Q1_CANLF
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.51	GO:0005549	odorant binding

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O02662|ADRB3_CANLF
Beta-3 adrenergic receptor
Search

ADRB3

0.96	Beta-3 adrenergic receptor

0.84	GO:0071875	adrenergic receptor signaling pathway
0.82	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.68	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.64	GO:0001659	temperature homeostasis
0.64	GO:0002024	diet induced thermogenesis
0.63	GO:0040015	negative regulation of multicellular organism growth
0.61	GO:0007190	activation of adenylate cyclase activity
0.60	GO:0045823	positive regulation of heart contraction
0.60	GO:0050873	brown fat cell differentiation
0.59	GO:1902533	positive regulation of intracellular signal transduction

0.85	GO:0004939	beta-adrenergic receptor activity
0.66	GO:0051380	norepinephrine binding
0.63	GO:0031690	adrenergic receptor binding
0.56	GO:0051379	epinephrine binding
0.53	GO:0042803	protein homodimerization activity
0.48	GO:0005057	signal transducer activity, downstream of receptor
0.47	GO:0030165	PDZ domain binding
0.47	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.44	GO:0046982	protein heterodimerization activity
0.36	GO:0050824	water binding

0.55	GO:0043235	receptor complex
0.54	GO:0005886	plasma membrane
0.48	GO:0005769	early endosome
0.37	GO:0005634	nucleus
0.35	GO:0045177	apical part of cell
0.34	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

0.35

EC:2.6.1

GO:0008483

sp|O02678|PGS1_CANLF
Biglycan
Search

BGN

0.96

Biglycan

0.60	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.49	GO:0046426	negative regulation of JAK-STAT cascade
0.47	GO:0006469	negative regulation of protein kinase activity
0.47	GO:0019221	cytokine-mediated signaling pathway
0.41	GO:0001974	blood vessel remodeling
0.37	GO:0030207	chondroitin sulfate catabolic process
0.37	GO:0030208	dermatan sulfate biosynthetic process
0.36	GO:0030206	chondroitin sulfate biosynthetic process
0.35	GO:0030198	extracellular matrix organization

0.57	GO:0050840	extracellular matrix binding
0.53	GO:0005539	glycosaminoglycan binding
0.48	GO:0004860	protein kinase inhibitor activity
0.35	GO:0005201	extracellular matrix structural constituent
0.31	GO:0005515	protein binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.56	GO:0042383	sarcolemma
0.54	GO:0030133	transport vesicle
0.53	GO:0009986	cell surface
0.51	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen

sp|O02720|LEP_CANLF
Leptin
Search

LEP

0.97

Leptin

0.74	GO:0010469	regulation of receptor activity
0.63	GO:1990051	activation of protein kinase C activity
0.62	GO:0032615	interleukin-12 production
0.62	GO:0072604	interleukin-6 secretion
0.62	GO:0032310	prostaglandin secretion
0.62	GO:0072606	interleukin-8 secretion
0.61	GO:0032868	response to insulin
0.61	GO:0032817	regulation of natural killer cell proliferation
0.61	GO:0090335	regulation of brown fat cell differentiation
0.60	GO:1900745	positive regulation of p38MAPK cascade

0.78	GO:0005179	hormone activity
0.48	GO:0051428	peptide hormone receptor binding
0.34	GO:0005125	cytokine activity

0.65	GO:0005576	extracellular region
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O02771|SMN_CANLF
Survival motor neuron protein
Search

SMN1

0.87	Survival of motor neuron

0.69	GO:0006397	mRNA processing
0.49	GO:0007399	nervous system development
0.48	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.48	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.48	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.48	GO:0000904	cell morphogenesis involved in differentiation
0.48	GO:0051960	regulation of nervous system development
0.48	GO:0060284	regulation of cell development
0.47	GO:0007019	microtubule depolymerization
0.47	GO:0033120	positive regulation of RNA splicing

0.59	GO:0003723	RNA binding
0.39	GO:0042802	identical protein binding
0.37	GO:0017134	fibroblast growth factor binding

0.61	GO:0005634	nucleus
0.50	GO:0032797	SMN complex
0.49	GO:0043204	perikaryon
0.49	GO:0034719	SMN-Sm protein complex
0.49	GO:0030018	Z disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0043005	neuron projection
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0005829	cytosol
0.41	GO:0044446	intracellular organelle part

sp|O02812|MK14_CANLF
Mitogen-activated protein kinase 14
Search

MAPK14

0.57	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.59	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration
0.59	GO:2001184	positive regulation of interleukin-12 secretion
0.58	GO:0090336	positive regulation of brown fat cell differentiation
0.58	GO:1905050	positive regulation of metallopeptidase activity
0.58	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.58	GO:0090400	stress-induced premature senescence
0.58	GO:1901741	positive regulation of myoblast fusion
0.58	GO:0071223	cellular response to lipoteichoic acid
0.57	GO:0010759	positive regulation of macrophage chemotaxis

0.81	GO:0004707	MAP kinase activity
0.59	GO:0048273	mitogen-activated protein kinase p38 binding
0.59	GO:0051525	NFAT protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0019903	protein phosphatase binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004708	MAP kinase kinase activity
0.34	GO:0008022	protein C-terminus binding

0.53	GO:0016607	nuclear speck
0.52	GO:0000922	spindle pole
0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|O02813|NPY1R_CANLF
Neuropeptide Y receptor type 1
Search

NPY1R

0.97	Neuropeptide Y receptor type 1

0.78	GO:0007218	neuropeptide signaling pathway
0.58	GO:0003151	outflow tract morphogenesis
0.58	GO:0007631	feeding behavior
0.57	GO:0019233	sensory perception of pain
0.56	GO:0040014	regulation of multicellular organism growth
0.56	GO:0008015	blood circulation
0.55	GO:0007626	locomotory behavior
0.50	GO:0006006	glucose metabolic process
0.46	GO:0065008	regulation of biological quality
0.46	GO:0007268	chemical synaptic transmission

0.83	GO:0004983	neuropeptide Y receptor activity
0.42	GO:0042923	neuropeptide binding
0.34	GO:0017046	peptide hormone binding
0.33	GO:0005515	protein binding

0.37	GO:0005886	plasma membrane
0.35	GO:0008021	synaptic vesicle
0.35	GO:0030424	axon
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|O18733|MMP9_CANLF
Matrix metalloproteinase-9
Search

0.56	Matrix metalloproteinase

0.80	GO:0030574	collagen catabolic process
0.75	GO:0001503	ossification
0.75	GO:0050900	leukocyte migration
0.61	GO:0006508	proteolysis
0.53	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.53	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.53	GO:1900122	positive regulation of receptor binding
0.53	GO:0051549	positive regulation of keratinocyte migration
0.52	GO:0035987	endodermal cell differentiation
0.52	GO:0090200	positive regulation of release of cytochrome c from mitochondria

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.46	GO:0042802	identical protein binding
0.32	GO:0005518	collagen binding
0.32	GO:0004252	serine-type endopeptidase activity

0.74	GO:0031012	extracellular matrix
0.47	GO:0005615	extracellular space
0.37	GO:0030017	sarcomere
0.35	GO:0005581	collagen trimer
0.34	GO:0005739	mitochondrion
0.34	GO:0005886	plasma membrane
0.33	GO:1904724	tertiary granule lumen
0.33	GO:1904813	ficolin-1-rich granule lumen
0.32	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.70

EC:3.4.24

GO:0004222

sp|O18735|ERBB2_CANLF
Receptor tyrosine-protein kinase erbB-2
Search

ERBB2

0.66	Receptor protein-tyrosine kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.76	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.63	GO:0023014	signal transduction by protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.60	GO:0033088	negative regulation of immature T cell proliferation in thymus
0.59	GO:0090314	positive regulation of protein targeting to membrane
0.58	GO:0042552	myelination
0.58	GO:0045945	positive regulation of transcription by RNA polymerase III
0.58	GO:0007422	peripheral nervous system development
0.58	GO:0071364	cellular response to epidermal growth factor stimulus

0.83	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.79	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.60	GO:0001042	RNA polymerase I core binding
0.55	GO:0019903	protein phosphatase binding
0.55	GO:0008022	protein C-terminus binding
0.54	GO:0019838	growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0043209	myelin sheath
0.54	GO:0016323	basolateral plasma membrane
0.54	GO:0016324	apical plasma membrane
0.53	GO:0043235	receptor complex
0.52	GO:0010008	endosome membrane
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.41	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0045178	basal part of cell
0.36	GO:0005902	microvillus

0.83	EC:2.7.10	GO:0004716
0.36	KEGG:R04545	GO:0046934

sp|O18740|K1C9_CANLF
Keratin, type I cytoskeletal 9
Search

0.92	LOW QUALITY PROTEIN: keratin, type I cytoskeletal 9

0.56	GO:0043588	skin development
0.53	GO:0045109	intermediate filament organization
0.47	GO:0009913	epidermal cell differentiation
0.46	GO:0018149	peptide cross-linking
0.38	GO:0007283	spermatogenesis
0.37	GO:0043627	response to estrogen
0.37	GO:0045214	sarcomere organization
0.37	GO:0012501	programmed cell death
0.36	GO:0042633	hair cycle
0.36	GO:0007568	aging

0.61	GO:0005198	structural molecule activity
0.39	GO:0097110	scaffold protein binding
0.37	GO:1990254	keratin filament binding
0.34	GO:0008092	cytoskeletal protein binding
0.34	GO:0009982	pseudouridine synthase activity
0.33	GO:0003723	RNA binding
0.32	GO:0005230	extracellular ligand-gated ion channel activity
0.32	GO:0030246	carbohydrate binding
0.32	GO:0004386	helicase activity
0.32	GO:0099600	transmembrane receptor activity

0.78	GO:0005882	intermediate filament
0.47	GO:0001533	cornified envelope
0.40	GO:0070062	extracellular exosome
0.37	GO:0043034	costamere
0.36	GO:1990357	terminal web
0.36	GO:0016327	apicolateral plasma membrane
0.36	GO:0045178	basal part of cell
0.36	GO:0005634	nucleus
0.36	GO:0042383	sarcolemma
0.36	GO:0030018	Z disc

0.34

EC:5.4.99.12

GO:0009982

sp|O18806|FA8_CANLF
Coagulation factor VIII
Search

0.57	Coagulation factor VIII

0.85	GO:0030168	platelet activation
0.49	GO:0055114	oxidation-reduction process
0.40	GO:0006953	acute-phase response
0.34	GO:0007597	blood coagulation, intrinsic pathway

0.66	GO:0005507	copper ion binding
0.49	GO:0016491	oxidoreductase activity

0.38	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0016491

sp|O18835|BGLR_CANLF
Beta-glucuronidase
Search

GUSB

0.51	Beta-glucuronidase

0.60	GO:0005975	carbohydrate metabolic process
0.36	GO:0046677	response to antibiotic
0.36	GO:0006027	glycosaminoglycan catabolic process
0.36	GO:0006907	pinocytosis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008333	endosome to lysosome transport
0.35	GO:0030212	hyaluronan metabolic process
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0046395	carboxylic acid catabolic process
0.32	GO:0006334	nucleosome assembly

0.81	GO:0004566	beta-glucuronidase activity
0.50	GO:0019904	protein domain specific binding
0.49	GO:0005102	receptor binding
0.34	GO:0030246	carbohydrate binding
0.31	GO:0003677	DNA binding

0.74	GO:0005764	lysosome
0.49	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:0009986	cell surface
0.34	GO:0005783	endoplasmic reticulum
0.32	GO:0000786	nucleosome
0.31	GO:0005634	nucleus

0.81

EC:3.2.1.31

GO:0004566

sp|O18840|ACTB_CANLF
Actin, cytoplasmic 1
Search

ACTB

0.64	Beta-actin variant 2

0.53	GO:0098974	postsynaptic actin cytoskeleton organization
0.52	GO:0072749	cellular response to cytochalasin B
0.49	GO:0032091	negative regulation of protein binding
0.46	GO:0045214	sarcomere organization
0.46	GO:0071346	cellular response to interferon-gamma
0.44	GO:0048870	cell motility
0.39	GO:0070527	platelet aggregation
0.39	GO:0001895	retina homeostasis
0.37	GO:0021762	substantia nigra development
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.53	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0030957	Tat protein binding
0.51	GO:0050998	nitric-oxide synthase binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008144	drug binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019894	kinesin binding
0.49	GO:0005522	profilin binding

0.76	GO:0097433	dense body
0.70	GO:0005925	focal adhesion
0.61	GO:0005856	cytoskeleton
0.53	GO:0043209	myelin sheath
0.50	GO:0005886	plasma membrane
0.47	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0070062	extracellular exosome
0.46	GO:0044448	cell cortex part
0.45	GO:0005829	cytosol

sp|O18873|ALL1_CANLF
Major allergen Can f 1
Search

LCN1

0.97	Late lactation protein B

0.44	GO:0050909	sensory perception of taste
0.39	GO:0001895	retina homeostasis
0.38	GO:0015909	long-chain fatty acid transport
0.37	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0050896	response to stimulus
0.35	GO:0006508	proteolysis

0.56	GO:0031404	chloride ion binding
0.51	GO:0036094	small molecule binding
0.49	GO:0005102	receptor binding
0.45	GO:0008270	zinc ion binding
0.38	GO:0004869	cysteine-type endopeptidase inhibitor activity

0.50	GO:0005576	extracellular region
0.36	GO:0031982	vesicle

sp|O18874|ALL2_CANLF
Minor allergen Can f 2
Search

0.18	Minor allergen Can f 2

0.51	GO:0036094	small molecule binding
0.43	GO:0005501	retinoid binding

0.56

GO:0005576

extracellular region

sp|O18914|OPSR_CANLF
Long-wave-sensitive opsin 1
Search

0.91	Red-green sensitive cone visual pigment

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0009584	detection of visible light
0.39	GO:0032467	positive regulation of cytokinesis
0.36	GO:0001523	retinoid metabolic process

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.39	GO:0042802	identical protein binding

0.53	GO:0001750	photoreceptor outer segment
0.37	GO:0060170	ciliary membrane
0.34	GO:0005887	integral component of plasma membrane

sp|O18921|RENBP_CANLF
N-acylglucosamine 2-epimerase (Fragment)
Search

0.57	N-acylglucosamine 2-epimerase (Fragment)

0.60	GO:0006044	N-acetylglucosamine metabolic process
0.49	GO:0010951	negative regulation of endopeptidase activity
0.46	GO:0019262	N-acetylneuraminate catabolic process
0.43	GO:0006050	mannosamine metabolic process
0.38	GO:0008217	regulation of blood pressure
0.37	GO:0006048	UDP-N-acetylglucosamine biosynthetic process
0.35	GO:0006468	protein phosphorylation

0.69	GO:0050121	N-acylglucosamine 2-epimerase activity
0.49	GO:0004866	endopeptidase inhibitor activity
0.41	GO:0042803	protein homodimerization activity
0.39	GO:0008080	N-acetyltransferase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004672	protein kinase activity
0.34	GO:0003676	nucleic acid binding

0.42	GO:0071339	MLL1 complex
0.41	GO:0048188	Set1C/COMPASS complex
0.40	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol

0.69

EC:5.1.3.8

GO:0050121

sp|O19000|MT1_CANLF
Metallothionein-1
Search

0.74	Metallothionein-II, hippocampal

0.65	GO:0071294	cellular response to zinc ion
0.57	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.48	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.41	GO:0035690	cellular response to drug
0.41	GO:0046688	response to copper ion
0.40	GO:0007263	nitric oxide mediated signal transduction
0.40	GO:0097501	stress response to metal ion
0.39	GO:0006882	cellular zinc ion homeostasis

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.55	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0005764	lysosome

sp|O19133|G6PC_CANLF
Glucose-6-phosphatase
Search

G6PC

0.84	Acipenser baerii glucose-6-phosphatase mRNA

0.67	GO:0016311	dephosphorylation
0.63	GO:0019319	hexose biosynthetic process
0.62	GO:0006006	glucose metabolic process
0.57	GO:0015712	hexose phosphate transport
0.54	GO:0042593	glucose homeostasis
0.54	GO:0046415	urate metabolic process
0.53	GO:0035264	multicellular organism growth
0.53	GO:0042632	cholesterol homeostasis
0.52	GO:0006641	triglyceride metabolic process
0.51	GO:0005980	glycogen catabolic process

0.85	GO:0004346	glucose-6-phosphatase activity
0.51	GO:0042301	phosphate ion binding
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0008131	primary amine oxidase activity
0.34	GO:0048038	quinone binding
0.34	GO:0005507	copper ion binding
0.33	GO:0097371	MDM2/MDM4 family protein binding
0.33	GO:0061133	endopeptidase activator activity
0.33	GO:0002039	p53 binding
0.32	GO:0042802	identical protein binding

0.61	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0008537	proteasome activator complex
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.85	EC:3.1.3.9	GO:0004346
0.85	KEGG:R00303	GO:0004346

sp|O19177|U119A_CANLF
Protein unc-119 homolog A
Search

UNC119

0.97	Unc-119 lipid binding chaperone

0.74	GO:0007399	nervous system development
0.57	GO:0061098	positive regulation of protein tyrosine kinase activity
0.54	GO:0042953	lipoprotein transport
0.53	GO:0000281	mitotic cytokinesis
0.46	GO:0070121	Kupffer's vesicle development
0.46	GO:0007601	visual perception
0.44	GO:0030154	cell differentiation
0.43	GO:2001287	negative regulation of caveolin-mediated endocytosis
0.43	GO:1900186	negative regulation of clathrin-dependent endocytosis
0.38	GO:0006897	endocytosis

0.49	GO:0008289	lipid binding
0.35	GO:0005515	protein binding

0.55	GO:0045171	intercellular bridge
0.55	GO:0051233	spindle midzone
0.52	GO:0000922	spindle pole
0.52	GO:0005813	centrosome
0.34	GO:0005737	cytoplasm
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:1902494	catalytic complex
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|O19179|GUC2D_CANLF
Retinal guanylyl cyclase 1
Search

GUCY2D

0.57	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.47	GO:0007601	visual perception
0.45	GO:0050962	detection of light stimulus involved in sensory perception
0.44	GO:0035845	photoreceptor cell outer segment organization
0.43	GO:0009584	detection of visible light

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004016	adenylate cyclase activity

0.49	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:4.6.1.2

GO:0004383

sp|O46392|CO1A2_CANLF
Collagen alpha-2(I) chain
Search

COL1A2

0.83	Type IIA procollagen

0.67	GO:0009612	response to mechanical stimulus
0.40	GO:0043589	skin morphogenesis
0.39	GO:0033339	pectoral fin development
0.39	GO:0033334	fin morphogenesis
0.39	GO:0031101	fin regeneration
0.39	GO:0030199	collagen fibril organization
0.39	GO:0007266	Rho protein signal transduction
0.38	GO:0030278	regulation of ossification
0.38	GO:0007179	transforming growth factor beta receptor signaling pathway
0.38	GO:0008217	regulation of blood pressure

0.82	GO:0005201	extracellular matrix structural constituent
0.39	GO:0048407	platelet-derived growth factor binding
0.39	GO:0002020	protease binding
0.38	GO:0030674	protein binding, bridging
0.37	GO:0042802	identical protein binding

0.62	GO:0005581	collagen trimer
0.39	GO:0098643	banded collagen fibril
0.37	GO:0005615	extracellular space
0.36	GO:0005783	endoplasmic reticulum

sp|O46501|PRIO_CANLF
Major prion protein
Search

PRNP

0.89	Major prion protein

0.78	GO:0051260	protein homooligomerization
0.39	GO:1902938	regulation of intracellular calcium activated chloride channel activity
0.39	GO:0071280	cellular response to copper ion
0.39	GO:1904646	cellular response to amyloid-beta
0.39	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.39	GO:0043525	positive regulation of neuron apoptotic process
0.38	GO:0031648	protein destabilization
0.38	GO:0061098	positive regulation of protein tyrosine kinase activity
0.37	GO:1902951	negative regulation of dendritic spine maintenance
0.37	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade

0.54	GO:0046872	metal ion binding
0.45	GO:0008017	microtubule binding
0.39	GO:0031802	type 5 metabotropic glutamate receptor binding
0.38	GO:0001540	amyloid-beta binding
0.37	GO:0032403	protein complex binding
0.37	GO:0042802	identical protein binding
0.36	GO:0002020	protease binding
0.35	GO:0005539	glycosaminoglycan binding
0.34	GO:0004872	receptor activity
0.34	GO:0004871	signal transducer activity

0.56	GO:0005886	plasma membrane
0.47	GO:0098857	membrane microdomain
0.46	GO:0031225	anchored component of membrane
0.44	GO:0005794	Golgi apparatus
0.39	GO:0106003	amyloid-beta complex
0.38	GO:0016234	inclusion body
0.38	GO:0030425	dendrite
0.37	GO:0031965	nuclear membrane
0.37	GO:0009986	cell surface
0.36	GO:0005829	cytosol

sp|O46550|CAV2_CANLF
Caveolin-2
Search

CAV2

0.83

Caveolin

0.85	GO:0070836	caveola assembly
0.70	GO:0060161	positive regulation of dopamine receptor signaling pathway
0.67	GO:0001937	negative regulation of endothelial cell proliferation
0.67	GO:0048741	skeletal muscle fiber development
0.64	GO:0007029	endoplasmic reticulum organization
0.64	GO:0006906	vesicle fusion
0.63	GO:0044789	modulation by host of viral release from host cell
0.62	GO:0048278	vesicle docking
0.61	GO:1902188	positive regulation of viral release from host cell
0.61	GO:0044794	positive regulation by host of viral process

0.63	GO:0031748	D1 dopamine receptor binding
0.60	GO:0097110	scaffold protein binding
0.57	GO:0032947	protein complex scaffold activity
0.56	GO:0030674	protein binding, bridging
0.55	GO:0019901	protein kinase binding
0.54	GO:0042803	protein homodimerization activity
0.53	GO:0046982	protein heterodimerization activity
0.35	GO:0051219	phosphoprotein binding
0.35	GO:0019905	syntaxin binding
0.33	GO:0044325	ion channel binding

0.84	GO:0005901	caveola
0.73	GO:0000139	Golgi membrane
0.62	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.62	GO:0048471	perinuclear region of cytoplasm
0.61	GO:0002080	acrosomal membrane
0.57	GO:0005925	focal adhesion
0.55	GO:0030133	transport vesicle
0.49	GO:0005887	integral component of plasma membrane
0.46	GO:0005634	nucleus
0.46	GO:0043234	protein complex

sp|O46607|GPX5_CANLF
Epididymal secretory glutathione peroxidase
Search

0.47	Epididymal secretory glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0051289	protein homotetramerization
0.45	GO:0033554	cellular response to stress
0.43	GO:0042744	hydrogen peroxide catabolic process
0.35	GO:0010269	response to selenium ion
0.35	GO:0051412	response to corticosterone
0.35	GO:0002238	response to molecule of fungal origin
0.34	GO:0006749	glutathione metabolic process

0.79	GO:0004602	glutathione peroxidase activity
0.50	GO:0008430	selenium binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.33	GO:0004556	alpha-amylase activity
0.32	GO:0043169	cation binding

0.56	GO:0097524	sperm plasma membrane
0.54	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.79

EC:1.11.1.9

GO:0004602

sp|O46612|IL1A_CANLF
Interleukin-1 alpha
Search

IL1A

0.83	Interleukin-1 alpha

0.86	GO:0001660	fever generation
0.83	GO:0051781	positive regulation of cell division
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.64	GO:0046688	response to copper ion
0.64	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.64	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.64	GO:0034605	cellular response to heat
0.64	GO:2000391	positive regulation of neutrophil extravasation
0.63	GO:0071639	positive regulation of monocyte chemotactic protein-1 production

0.86	GO:0005149	interleukin-1 receptor binding
0.80	GO:0005125	cytokine activity
0.58	GO:0005507	copper ion binding

0.73	GO:0005615	extracellular space
0.68	GO:0005829	cytosol
0.35	GO:0009986	cell surface
0.33	GO:0005886	plasma membrane

sp|O46634|CD166_CANLF
CD166 antigen (Fragment)
Search

ALCAM

0.97	Activated leukocyte cell adhesion molecule

0.66	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.61	GO:0008045	motor neuron axon guidance

0.57

GO:0042802

identical protein binding

0.67	GO:0042101	T cell receptor complex
0.66	GO:0001772	immunological synapse
0.59	GO:0009897	external side of plasma membrane
0.59	GO:0043025	neuronal cell body
0.58	GO:0030424	axon
0.53	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O46635|5HT2A_CANLF
5-hydroxytryptamine receptor 2A
Search

HTR2A

0.97	5-hydroxytryptamine (Serotonin) receptor 2 A

0.81	GO:0006939	smooth muscle contraction
0.80	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.79	GO:0050795	regulation of behavior
0.78	GO:0046883	regulation of hormone secretion
0.60	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.59	GO:0007202	activation of phospholipase C activity
0.57	GO:0051209	release of sequestered calcium ion into cytosol
0.57	GO:0014065	phosphatidylinositol 3-kinase signaling
0.56	GO:0045821	positive regulation of glycolytic process
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.80	GO:0099589	serotonin receptor activity
0.77	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.77	GO:0008227	G-protein coupled amine receptor activity
0.61	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
0.59	GO:0051378	serotonin binding
0.40	GO:0001965	G-protein alpha-subunit binding
0.38	GO:0032403	protein complex binding
0.36	GO:0018738	S-formylglutathione hydrolase activity
0.36	GO:0104005	hijacked molecular function

0.82	GO:0043198	dendritic shaft
0.63	GO:0005887	integral component of plasma membrane
0.45	GO:0005901	caveola
0.44	GO:0030424	axon
0.42	GO:0031410	cytoplasmic vesicle
0.41	GO:0070852	cell body fiber
0.39	GO:0043025	neuronal cell body
0.37	GO:0005829	cytosol

0.36	EC:3.1.2.12	GO:0018738
0.36	KEGG:R00527	GO:0018738

sp|O46669|SCNAA_CANLF
Sodium channel protein type 10 subunit alpha
Search

SCN10A

0.62	Sodium channel protein type 10 subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0035725	sodium ion transmembrane transport
0.75	GO:0019233	sensory perception of pain
0.65	GO:0086043	bundle of His cell action potential
0.64	GO:0086016	AV node cell action potential
0.64	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.61	GO:0055117	regulation of cardiac muscle contraction
0.60	GO:0002027	regulation of heart rate
0.55	GO:0019228	neuronal action potential
0.55	GO:0086010	membrane depolarization during action potential

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.72	GO:0022839	ion gated channel activity
0.72	GO:0008381	mechanosensitive ion channel activity
0.60	GO:0044325	ion channel binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.42	GO:0044299	C-fiber
0.41	GO:0071439	clathrin complex
0.39	GO:0070062	extracellular exosome

sp|O46674|AT2A2_CANLF
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Search

ATP2A2

0.53	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.57	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration
0.57	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter
0.56	GO:0033292	T-tubule organization
0.56	GO:0014883	transition between fast and slow fiber
0.55	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.55	GO:0008016	regulation of heart contraction
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0014887	cardiac muscle adaptation

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0044548	S100 protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019899	enzyme binding
0.47	GO:0005509	calcium ion binding
0.39	GO:0031775	lutropin-choriogonadotropic hormone receptor binding
0.37	GO:0008022	protein C-terminus binding

0.56	GO:0097470	ribbon synapse
0.54	GO:0016529	sarcoplasmic reticulum
0.48	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005654	nucleoplasm
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0090534	calcium ion-transporting ATPase complex
0.38	GO:0014704	intercalated disc
0.37	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0012506	vesicle membrane

0.80

EC:3.6.3.8

GO:0005388

sp|O62671|CP241_CANLF
Cytochrome P450 2C41
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.57	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0042738	exogenous drug catabolic process
0.43	GO:0008202	steroid metabolic process
0.43	GO:0016098	monoterpenoid metabolic process
0.42	GO:0002933	lipid hydroxylation
0.42	GO:0070988	demethylation
0.41	GO:0043651	linoleic acid metabolic process
0.37	GO:0006805	xenobiotic metabolic process
0.37	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.47	GO:0034875	caffeine oxidase activity
0.38	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|O62682|FGF8_CANLF
Fibroblast growth factor 8 (Fragment)
Search

FGF8

0.50	Fibroblast growth factor (Fragment)

0.83	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.55	GO:0030917	midbrain-hindbrain boundary development
0.55	GO:0030916	otic vesicle formation
0.54	GO:0090133	mesendoderm migration
0.54	GO:0030878	thyroid gland development
0.54	GO:0060037	pharyngeal system development
0.54	GO:0060128	corticotropin hormone secreting cell differentiation
0.54	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation
0.53	GO:0021798	forebrain dorsal/ventral pattern formation

0.84	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0042056	chemoattractant activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.39	GO:0005764	lysosome
0.36	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|O62683|ZO3_CANLF
Tight junction protein ZO-3
Search

TJP3

0.94	Tight junction protein ZO-3

0.40	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.38	GO:0001825	blastocyst formation
0.37	GO:0007605	sensory perception of sound
0.34	GO:0007043	cell-cell junction assembly
0.34	GO:1901350	cell-cell signaling involved in cell-cell junction organization
0.33	GO:0071000	response to magnetism
0.33	GO:0090557	establishment of endothelial intestinal barrier
0.33	GO:0043116	negative regulation of vascular permeability
0.33	GO:0071277	cellular response to calcium ion
0.33	GO:2000810	regulation of bicellular tight junction assembly

0.38	GO:0071253	connexin binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0005516	calmodulin binding
0.33	GO:0008022	protein C-terminus binding
0.33	GO:0045296	cadherin binding

0.80	GO:0005923	bicellular tight junction
0.47	GO:0005634	nucleus
0.42	GO:0016324	apical plasma membrane
0.38	GO:0009986	cell surface
0.38	GO:0046581	intercellular canaliculus
0.38	GO:0016327	apicolateral plasma membrane
0.38	GO:0014704	intercalated disc
0.38	GO:0005913	cell-cell adherens junction
0.36	GO:0005829	cytosol
0.34	GO:0043234	protein complex

sp|O62699|NOS2_CANLF
Nitric oxide synthase, inducible
Search

NOS2

0.72	Nitric oxide synthase

0.83	GO:0006809	nitric oxide biosynthetic process
0.62	GO:0072604	interleukin-6 secretion
0.62	GO:0032310	prostaglandin secretion
0.62	GO:0072606	interleukin-8 secretion
0.61	GO:0018119	peptidyl-cysteine S-nitrosylation
0.60	GO:1900015	regulation of cytokine production involved in inflammatory response
0.57	GO:0009617	response to bacterium
0.56	GO:0071346	cellular response to interferon-gamma
0.55	GO:0050796	regulation of insulin secretion
0.55	GO:0098542	defense response to other organism

0.84	GO:0004517	nitric-oxide synthase activity
0.77	GO:0005516	calmodulin binding
0.69	GO:0010181	FMN binding
0.68	GO:0050661	NADP binding
0.64	GO:0050660	flavin adenine dinucleotide binding
0.62	GO:0020037	heme binding
0.61	GO:0005506	iron ion binding
0.60	GO:0034617	tetrahydrobiopterin binding
0.54	GO:0034618	arginine binding
0.51	GO:0042803	protein homodimerization activity

0.53	GO:0030863	cortical cytoskeleton
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.34	GO:0012506	vesicle membrane
0.34	GO:0005634	nucleus
0.34	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.84

EC:1.14.13.39

GO:0004517

sp|O62729|NPY5R_CANLF
Neuropeptide Y receptor type 5
Search

NPY5R

0.97	Neuropeptide Y receptor type 5

0.80	GO:0007218	neuropeptide signaling pathway
0.70	GO:0003214	cardiac left ventricle morphogenesis
0.67	GO:0003151	outflow tract morphogenesis
0.63	GO:0007268	chemical synaptic transmission
0.56	GO:0007631	feeding behavior
0.53	GO:0008015	blood circulation
0.49	GO:0060112	generation of ovulation cycle rhythm
0.48	GO:0014050	negative regulation of glutamate secretion
0.48	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.48	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus

0.84	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0016494	C-X-C chemokine receptor activity
0.33	GO:0050254	rhodopsin kinase activity
0.32	GO:0042923	neuropeptide binding

0.61	GO:0043005	neuron projection
0.38	GO:0005886	plasma membrane
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.11.14

GO:0050254

sp|O62732|SYN1_CANLF
Synapsin-1 (Fragment)
Search

SYN2

0.65	Synapsin II

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0051649	establishment of localization in cell
0.54	GO:0097479	synaptic vesicle localization
0.39	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.34	GO:0051588	regulation of neurotransmitter transport
0.33	GO:1902803	regulation of synaptic vesicle transport
0.33	GO:1903530	regulation of secretion by cell

0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.41	GO:0048306	calcium-dependent protein binding
0.41	GO:0003779	actin binding
0.36	GO:0046983	protein dimerization activity
0.33	GO:0046872	metal ion binding
0.32	GO:0005215	transporter activity

0.82	GO:0008021	synaptic vesicle
0.59	GO:0099501	exocytic vesicle membrane
0.57	GO:0014069	postsynaptic density
0.57	GO:0043209	myelin sheath
0.55	GO:0000795	synaptonemal complex
0.54	GO:0048786	presynaptic active zone
0.53	GO:0030424	axon
0.48	GO:0005856	cytoskeleton
0.43	GO:0031201	SNARE complex
0.41	GO:0030054	cell junction

sp|O62802|IL2RA_CANLF
Interleukin-2 receptor subunit alpha
Search

IL2RA

0.97	Interleukin-2 receptor subunit alpha

0.87	GO:0038110	interleukin-2-mediated signaling pathway
0.69	GO:0002664	regulation of T cell tolerance induction
0.65	GO:0046013	regulation of T cell homeostatic proliferation
0.65	GO:0006924	activation-induced cell death of T cells
0.63	GO:0042104	positive regulation of activated T cell proliferation
0.61	GO:0042130	negative regulation of T cell proliferation
0.60	GO:0050728	negative regulation of inflammatory response
0.59	GO:0007219	Notch signaling pathway
0.52	GO:0006954	inflammatory response
0.49	GO:0006955	immune response

0.87	GO:0004911	interleukin-2 receptor activity
0.87	GO:0019976	interleukin-2 binding
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0008144	drug binding
0.34	GO:0003735	structural constituent of ribosome

0.58	GO:0009897	external side of plasma membrane
0.34	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

sp|O77559|ADML_CANLF
ADM
Search

ADM

0.97	Adrenomedullin a

0.76	GO:0010469	regulation of receptor activity
0.67	GO:1990410	adrenomedullin receptor signaling pathway
0.67	GO:0097647	amylin receptor signaling pathway
0.67	GO:0045906	negative regulation of vasoconstriction
0.67	GO:0002031	G-protein coupled receptor internalization
0.66	GO:0035809	regulation of urine volume
0.65	GO:2001214	positive regulation of vasculogenesis
0.65	GO:0097084	vascular smooth muscle cell development
0.65	GO:0010460	positive regulation of heart rate
0.65	GO:0043116	negative regulation of vascular permeability

0.79	GO:0005179	hormone activity
0.70	GO:0031700	adrenomedullin receptor binding

0.66	GO:0005576	extracellular region
0.41	GO:0005737	cytoplasm

sp|O77560|PHOS_CANLF
Phosducin
Search

PDC

0.72	Phosducin b

0.57	GO:0008616	queuosine biosynthetic process
0.52	GO:0007601	visual perception
0.42	GO:0050896	response to stimulus
0.37	GO:0043086	negative regulation of catalytic activity
0.35	GO:0023052	signaling
0.35	GO:0007154	cell communication
0.34	GO:0050789	regulation of biological process

0.61	GO:0008479	queuine tRNA-ribosyltransferase activity
0.40	GO:0004859	phospholipase inhibitor activity

0.84	GO:0001750	photoreceptor outer segment
0.56	GO:0001917	photoreceptor inner segment
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus

0.61

EC:2.4.2.29

GO:0008479

sp|O77592|S35A3_CANLF
UDP-N-acetylglucosamine transporter
Search

SLC35A3

0.91	UDP-N-acetylglucosamine transporter

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.56	GO:1990569	UDP-N-acetylglucosamine transmembrane transport
0.34	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0005351	sugar:proton symporter activity
0.35	GO:0005462	UDP-N-acetylglucosamine transmembrane transporter activity
0.33	GO:0005515	protein binding

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O77616|MSHR_CANLF
Melanocyte-stimulating hormone receptor
Search

MC1R

0.69	Melanocyte-stimulating hormone receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0090037	positive regulation of protein kinase C signaling
0.39	GO:0010739	positive regulation of protein kinase A signaling
0.39	GO:0042438	melanin biosynthetic process
0.38	GO:0019233	sensory perception of pain
0.38	GO:0051897	positive regulation of protein kinase B signaling
0.38	GO:0043473	pigmentation
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0035556	intracellular signal transduction

0.85

GO:0004980

melanocyte-stimulating hormone receptor activity

0.56	GO:0005886	plasma membrane
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|O77621|ADA1A_CANLF
Alpha-1A adrenergic receptor (Fragment)
Search

ADRA1A

0.94	Alpha-1a adrenoceptor transcript variant 1

0.85	GO:0071875	adrenergic receptor signaling pathway
0.80	GO:0055117	regulation of cardiac muscle contraction
0.80	GO:0019229	regulation of vasoconstriction
0.69	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
0.66	GO:0045987	positive regulation of smooth muscle contraction
0.64	GO:1903524	positive regulation of blood circulation
0.64	GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
0.64	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.63	GO:1903995	regulation of non-membrane spanning protein tyrosine kinase activity
0.62	GO:0003057	regulation of the force of heart contraction by chemical signal

0.85	GO:0004935	adrenergic receptor activity
0.58	GO:0046982	protein heterodimerization activity

0.62	GO:0031965	nuclear membrane
0.56	GO:0005886	plasma membrane
0.42	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|O77645|STP2_CANLF
Nuclear transition protein 2
Search

TNP2

0.97	Nuclear transition protein 2

0.80	GO:0007283	spermatogenesis
0.68	GO:0030154	cell differentiation
0.66	GO:0007275	multicellular organism development
0.61	GO:0007341	penetration of zona pellucida
0.60	GO:0010954	positive regulation of protein processing
0.58	GO:0007340	acrosome reaction
0.57	GO:0043486	histone exchange
0.56	GO:0006997	nucleus organization
0.55	GO:0022412	cellular process involved in reproduction in multicellular organism
0.54	GO:0003006	developmental process involved in reproduction

0.55	GO:0003677	DNA binding
0.52	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen

sp|O77746|PDE5A_CANLF
cGMP-specific 3',5'-cyclic phosphodiesterase
Search

PDE5A

0.58	Phosphodiesterase

0.61	GO:0046069	cGMP catabolic process
0.60	GO:0007165	signal transduction
0.57	GO:0055118	negative regulation of cardiac muscle contraction
0.57	GO:0055119	relaxation of cardiac muscle
0.56	GO:0060282	positive regulation of oocyte development
0.55	GO:0014742	positive regulation of muscle hypertrophy
0.55	GO:0010611	regulation of cardiac muscle hypertrophy
0.55	GO:0030823	regulation of cGMP metabolic process
0.54	GO:0042130	negative regulation of T cell proliferation
0.52	GO:0043406	positive regulation of MAP kinase activity

0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.55	GO:0030553	cGMP binding
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.36

GO:0005829

cytosol

0.78

GO:0004114

sp|O77762|IL4_CANLF
Interleukin-4
Search

IL4

0.93	Interleukin-4

0.75	GO:0010469	regulation of receptor activity
0.75	GO:0042113	B cell activation
0.74	GO:0006955	immune response
0.56	GO:1903660	negative regulation of complement-dependent cytotoxicity
0.55	GO:0032736	positive regulation of interleukin-13 production
0.54	GO:0043011	myeloid dendritic cell differentiation
0.54	GO:1902105	regulation of leukocyte differentiation
0.54	GO:2000352	negative regulation of endothelial cell apoptotic process
0.53	GO:0010633	negative regulation of epithelial cell migration
0.52	GO:0002440	production of molecular mediator of immune response

0.86	GO:0005136	interleukin-4 receptor binding
0.78	GO:0008083	growth factor activity
0.72	GO:0005125	cytokine activity

0.66

GO:0005576

extracellular region

sp|O77808|V2R_CANLF
Vasopressin V2 receptor
Search

AVPR2

0.97	Vasopressin V2 receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0032609	interferon-gamma production
0.55	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.52	GO:0001992	regulation of systemic arterial blood pressure by vasopressin
0.52	GO:0034097	response to cytokine
0.49	GO:0045907	positive regulation of vasoconstriction
0.47	GO:1901652	response to peptide
0.45	GO:0032870	cellular response to hormone stimulus
0.42	GO:0035814	negative regulation of renal sodium excretion
0.42	GO:0035811	negative regulation of urine volume

0.85	GO:0005000	vasopressin receptor activity
0.46	GO:0042277	peptide binding
0.35	GO:0042562	hormone binding
0.34	GO:0005515	protein binding

0.48	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.35	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

sp|O97492|CATA_CANLF
Catalase
Search

CAT

0.54

Catalase

0.76	GO:0042744	hydrogen peroxide catabolic process
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.55	GO:0009650	UV protection
0.55	GO:0020027	hemoglobin metabolic process
0.53	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.53	GO:0051289	protein homotetramerization
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.77	GO:0004096	catalase activity
0.63	GO:0020037	heme binding
0.53	GO:0004046	aminoacylase activity
0.53	GO:0046872	metal ion binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0005102	receptor binding
0.47	GO:0019899	enzyme binding
0.47	GO:0050661	NADP binding
0.35	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity

0.52	GO:0005777	peroxisome
0.51	GO:0031903	microbody membrane
0.44	GO:0005739	mitochondrion
0.37	GO:0031970	organelle envelope lumen
0.37	GO:0005764	lysosome
0.36	GO:0005615	extracellular space
0.36	GO:0005925	focal adhesion
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum

0.77

EC:1.11.1.6

GO:0004096

sp|O97555|GDIA_CANLF
Rab GDP dissociation inhibitor alpha
Search

GDI1

0.68	Rab GDP dissociation inhibitor alpha

0.77	GO:0007264	small GTPase mediated signal transduction
0.76	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.55	GO:0090315	negative regulation of protein targeting to membrane
0.43	GO:0050771	negative regulation of axonogenesis
0.39	GO:0045773	positive regulation of axon extension
0.39	GO:0051592	response to calcium ion
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0043312	neutrophil degranulation

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.76	GO:0005096	GTPase activator activity
0.39	GO:0031267	small GTPase binding
0.33	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.53	GO:0043209	myelin sheath
0.50	GO:0030496	midbody
0.49	GO:0005737	cytoplasm
0.42	GO:0012505	endomembrane system
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0043025	neuronal cell body
0.38	GO:0030424	axon
0.35	GO:0043234	protein complex
0.35	GO:0031983	vesicle lumen
0.34	GO:0005925	focal adhesion

0.32

GO:0016740

sp|O97556|GDIB_CANLF
Rab GDP dissociation inhibitor beta
Search

GDI2

0.68	Rab GDP dissociation inhibitor beta

0.76	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.51	GO:0090315	negative regulation of protein targeting to membrane
0.43	GO:0050771	negative regulation of axonogenesis
0.39	GO:0045773	positive regulation of axon extension
0.38	GO:0051592	response to calcium ion
0.36	GO:0016192	vesicle-mediated transport
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0002283	neutrophil activation involved in immune response

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.76	GO:0005096	GTPase activator activity
0.40	GO:0031267	small GTPase binding
0.33	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.53	GO:0043209	myelin sheath
0.49	GO:0005737	cytoplasm
0.46	GO:0030496	midbody
0.44	GO:0012505	endomembrane system
0.40	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0043025	neuronal cell body
0.38	GO:0030424	axon
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen

sp|O97564|GBGT2_CANLF
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
Search

GNGT2

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0042462	eye photoreceptor cell development
0.42	GO:0007602	phototransduction
0.38	GO:0008104	protein localization
0.35	GO:0071377	cellular response to glucagon stimulus
0.32	GO:0055114	oxidation-reduction process

0.64	GO:0004871	signal transducer activity
0.45	GO:0003924	GTPase activity
0.33	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0005515	protein binding

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex

0.33

EC:1.3.99.3

GO:0003995

sp|O97571|CXCR2_CANLF
C-X-C chemokine receptor type 2
Search

0.97	High affinity interleukin-8 receptor B

0.84	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.71	GO:0006935	chemotaxis
0.56	GO:0038112	interleukin-8-mediated signaling pathway
0.52	GO:0031623	receptor internalization
0.49	GO:0045321	leukocyte activation
0.48	GO:0006968	cellular defense response
0.48	GO:1990266	neutrophil migration
0.45	GO:0008284	positive regulation of cell proliferation
0.44	GO:0043066	negative regulation of apoptotic process

0.85	GO:0016494	C-X-C chemokine receptor activity
0.80	GO:0019959	interleukin-8 binding
0.44	GO:0016493	C-C chemokine receptor activity
0.38	GO:0051916	granulocyte colony-stimulating factor binding
0.36	GO:0005044	scavenger receptor activity
0.33	GO:0008289	lipid binding

0.48	GO:0042629	mast cell granule
0.46	GO:0009986	cell surface
0.39	GO:0005886	plasma membrane
0.37	GO:0030667	secretory granule membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|O97578|CATC_CANLF
Dipeptidyl peptidase 1 (Fragment)
Search

CTSC

0.85	Prepro-cathepsin C

0.68	GO:0001913	T cell mediated cytotoxicity
0.63	GO:2001235	positive regulation of apoptotic signaling pathway
0.61	GO:0006508	proteolysis
0.59	GO:0006915	apoptotic process
0.46	GO:0044257	cellular protein catabolic process
0.37	GO:0007568	aging
0.37	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process
0.36	GO:0010033	response to organic substance

0.72	GO:0008234	cysteine-type peptidase activity
0.67	GO:0016505	peptidase activator activity involved in apoptotic process
0.54	GO:0004252	serine-type endopeptidase activity
0.38	GO:0031404	chloride ion binding
0.37	GO:0043621	protein self-association
0.37	GO:0019902	phosphatase binding
0.36	GO:0051087	chaperone binding
0.36	GO:0042802	identical protein binding

0.60	GO:0005813	centrosome
0.55	GO:0005654	nucleoplasm
0.49	GO:0005764	lysosome
0.46	GO:0005615	extracellular space
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0008234

sp|O97592|DMD_CANLF
Dystrophin
Search

DMD

0.70	Dystrophin

0.52	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
0.51	GO:0021629	olfactory nerve structural organization
0.51	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.51	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.50	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.50	GO:0008065	establishment of blood-nerve barrier
0.50	GO:0035994	response to muscle stretch
0.50	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.50	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.49	GO:0045213	neurotransmitter receptor metabolic process

0.86	GO:0002162	dystroglycan binding
0.74	GO:0003779	actin binding
0.59	GO:0008270	zinc ion binding
0.50	GO:0050998	nitric-oxide synthase binding
0.43	GO:0017166	vinculin binding
0.43	GO:0005521	lamin binding
0.42	GO:0008307	structural constituent of muscle
0.42	GO:0030165	PDZ domain binding
0.42	GO:0005178	integrin binding
0.42	GO:0017022	myosin binding

0.63	GO:0045211	postsynaptic membrane
0.60	GO:0030054	cell junction
0.56	GO:0005856	cytoskeleton
0.50	GO:0042383	sarcolemma
0.48	GO:0044306	neuron projection terminus
0.48	GO:0030018	Z disc
0.48	GO:0016010	dystrophin-associated glycoprotein complex
0.47	GO:0098857	membrane microdomain
0.44	GO:0099617	matrix side of mitochondrial inner membrane
0.43	GO:0097449	astrocyte projection

sp|O97626|CD40L_CANLF
CD40 ligand
Search

0.82	GO:0042100	B cell proliferation
0.79	GO:0030168	platelet activation
0.75	GO:0006954	inflammatory response
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.73	GO:0032753	positive regulation of interleukin-4 production
0.72	GO:0007257	activation of JUN kinase activity
0.72	GO:0032733	positive regulation of interleukin-10 production
0.72	GO:0048305	immunoglobulin secretion
0.70	GO:2000353	positive regulation of endothelial cell apoptotic process

0.85	GO:0005174	CD40 receptor binding
0.84	GO:0005164	tumor necrosis factor receptor binding
0.79	GO:0005125	cytokine activity

0.72	GO:0005615	extracellular space
0.65	GO:0009897	external side of plasma membrane
0.41	GO:0005622	intracellular
0.36	GO:0044297	cell body
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0042995	cell projection

sp|O97758|ZO1_CANLF
Tight junction protein ZO-1
Search

TJP1

0.88	Tight junction protein ZO-1

0.53	GO:0007605	sensory perception of sound
0.53	GO:0001825	blastocyst formation
0.40	GO:0071000	response to magnetism
0.40	GO:0090557	establishment of endothelial intestinal barrier
0.40	GO:0043116	negative regulation of vascular permeability
0.39	GO:0071333	cellular response to glucose stimulus
0.39	GO:0045471	response to ethanol
0.38	GO:0032496	response to lipopolysaccharide
0.38	GO:0007043	cell-cell junction assembly
0.38	GO:0042981	regulation of apoptotic process

0.57	GO:0071253	connexin binding
0.51	GO:0019904	protein domain specific binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0045296	cadherin binding
0.38	GO:0005516	calmodulin binding
0.33	GO:0016301	kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005923	bicellular tight junction
0.58	GO:0046581	intercellular canaliculus
0.56	GO:0016327	apicolateral plasma membrane
0.56	GO:0014704	intercalated disc
0.55	GO:0005913	cell-cell adherens junction
0.53	GO:0045177	apical part of cell
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.40	GO:0005921	gap junction

sp|O97799|KIT_CANLF
Mast/stem cell growth factor receptor Kit
Search

KIT

0.68	KIT proto-oncogene receptor tyrosine kinase

0.86	GO:0038109	Kit signaling pathway
0.85	GO:0038093	Fc receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0023014	signal transduction by protein phosphorylation
0.64	GO:0097326	melanocyte adhesion
0.63	GO:0002371	dendritic cell cytokine production
0.63	GO:0060374	mast cell differentiation
0.62	GO:0038162	erythropoietin-mediated signaling pathway
0.62	GO:0097324	melanocyte migration
0.62	GO:0032762	mast cell cytokine production

0.85	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.82	GO:0019955	cytokine binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.57	GO:0002020	protease binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.52	GO:0042803	protein homodimerization activity

0.59	GO:0042629	mast cell granule
0.55	GO:0009897	external side of plasma membrane
0.53	GO:0005911	cell-cell junction
0.51	GO:0005615	extracellular space
0.40	GO:0001669	acrosomal vesicle
0.39	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.10	GO:0004716
0.36	KEGG:R04545	GO:0046934

sp|O97863|IL33_CANLF
Interleukin-33
Search

IL33

0.97	Interleukin-33

0.76	GO:0010469	regulation of receptor activity
0.68	GO:0090197	positive regulation of chemokine secretion
0.67	GO:0043032	positive regulation of macrophage activation
0.61	GO:0002282	microglial cell activation involved in immune response
0.60	GO:0051025	negative regulation of immunoglobulin secretion
0.60	GO:0061518	microglial cell proliferation
0.60	GO:0050729	positive regulation of inflammatory response
0.59	GO:0002826	negative regulation of T-helper 1 type immune response
0.59	GO:0051024	positive regulation of immunoglobulin secretion
0.58	GO:0032736	positive regulation of interleukin-13 production

0.81	GO:0005125	cytokine activity
0.37	GO:0046556	alpha-L-arabinofuranosidase activity

0.45	GO:0030133	transport vesicle
0.44	GO:0005615	extracellular space
0.42	GO:0005694	chromosome
0.40	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

0.37

EC:3.2.1.55

GO:0046556

sp|O97945|IFNA3_CANLF
Interferon alpha-3
Search

0.87	Interferon-alpha

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.52	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.52	GO:0002323	natural killer cell activation involved in immune response
0.51	GO:0042100	B cell proliferation
0.51	GO:0002286	T cell activation involved in immune response
0.50	GO:0043330	response to exogenous dsRNA
0.50	GO:0030183	B cell differentiation
0.49	GO:0002250	adaptive immune response
0.49	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.46	GO:0032403	protein complex binding
0.33	GO:0005179	hormone activity

0.73

GO:0005615

extracellular space

sp|P00011|CYC_CANLF
Cytochrome c
Search

CYCS

0.72	Somatic cytochrome c

0.61	GO:0022900	electron transport chain
0.56	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0006119	oxidative phosphorylation
0.46	GO:0009060	aerobic respiration
0.43	GO:0006915	apoptotic process
0.43	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process
0.43	GO:0042743	hydrogen peroxide metabolic process
0.43	GO:0034465	response to carbon monoxide
0.42	GO:1901857	positive regulation of cellular respiration
0.42	GO:0002931	response to ischemia

0.65	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.38	GO:0019899	enzyme binding

0.62	GO:0070469	respiratory chain
0.61	GO:0005739	mitochondrion
0.60	GO:0031970	organelle envelope lumen
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.45	GO:0043209	myelin sheath

sp|P01002|IPSG_CANLF
Double-headed protease inhibitor, submandibular gland
Search

0.76	Double-headed protease inhibitor, submandibular gland

0.73	GO:0010951	negative regulation of endopeptidase activity
0.50	GO:1902572	negative regulation of serine-type peptidase activity
0.50	GO:1900003	regulation of serine-type endopeptidase activity
0.50	GO:0060046	regulation of acrosome reaction
0.42	GO:0006508	proteolysis
0.35	GO:0043113	receptor clustering
0.35	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.35	GO:0007422	peripheral nervous system development
0.35	GO:0009952	anterior/posterior pattern specification
0.35	GO:0007409	axonogenesis

0.76	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0008233	peptidase activity
0.36	GO:0005509	calcium ion binding
0.36	GO:0043236	laminin binding
0.34	GO:0017171	serine hydrolase activity
0.32	GO:0016740	transferase activity

0.60	GO:0005576	extracellular region
0.48	GO:0001669	acrosomal vesicle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.42

GO:0008233

sp|P01299|PAHO_CANLF
Pancreatic prohormone
Search

PPY

0.97	Pancreatic polypeptide

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0032098	regulation of appetite
0.56	GO:0007631	feeding behavior
0.56	GO:0007586	digestion
0.54	GO:0007218	neuropeptide signaling pathway
0.51	GO:0007267	cell-cell signaling
0.37	GO:0009306	protein secretion

0.79	GO:0005179	hormone activity
0.63	GO:0001664	G-protein coupled receptor binding

0.66	GO:0005576	extracellular region
0.41	GO:0005737	cytoplasm

sp|P01321|INS_CANLF
Insulin
Search

INS

0.96

Insulin

0.76	GO:0010469	regulation of receptor activity
0.70	GO:0006006	glucose metabolic process
0.50	GO:0045818	negative regulation of glycogen catabolic process
0.50	GO:0010243	response to organonitrogen compound
0.50	GO:0050995	negative regulation of lipid catabolic process
0.50	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.50	GO:1902952	positive regulation of dendritic spine maintenance
0.50	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.49	GO:2000252	negative regulation of feeding behavior
0.49	GO:0046628	positive regulation of insulin receptor signaling pathway

0.79	GO:0005179	hormone activity
0.53	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0005158	insulin receptor binding
0.49	GO:0002020	protease binding
0.44	GO:0042802	identical protein binding
0.36	GO:0051087	chaperone binding

0.66	GO:0005576	extracellular region
0.41	GO:0030141	secretory granule
0.39	GO:0060205	cytoplasmic vesicle lumen
0.37	GO:0005829	cytosol
0.36	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0031904	endosome lumen
0.36	GO:0005796	Golgi lumen
0.36	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0030133	transport vesicle

sp|P01353|GAST_CANLF
Gastrin
Search

GAST

0.97

Gastrin

0.74	GO:0010469	regulation of receptor activity
0.63	GO:0032094	response to food
0.50	GO:0007186	G-protein coupled receptor signaling pathway

0.78

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P01618|KV1_CANLF
Ig kappa chain V region GOM
Search

0.96	Ig kappa chain V region GOM

0.69	GO:0002250	adaptive immune response
0.68	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.67	GO:0038095	Fc-epsilon receptor signaling pathway
0.66	GO:0002377	immunoglobulin production
0.65	GO:0030449	regulation of complement activation
0.63	GO:0002449	lymphocyte mediated immunity
0.63	GO:0006956	complement activation
0.62	GO:0050900	leukocyte migration
0.55	GO:0006898	receptor-mediated endocytosis
0.49	GO:0006508	proteolysis

0.77	GO:0003823	antigen binding
0.54	GO:0004252	serine-type endopeptidase activity
0.39	GO:0046872	metal ion binding

0.63	GO:0005615	extracellular space
0.52	GO:1903561	extracellular vesicle
0.49	GO:0005886	plasma membrane

0.54

GO:0004252

sp|P01784|HV01_CANLF
Ig heavy chain V region GOM
Search

0.86	Myosin-reactive immunoglobulin heavy chain variable region (Fragment)

0.83	GO:0006958	complement activation, classical pathway
0.81	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.81	GO:0006909	phagocytosis
0.76	GO:0038094	Fc-gamma receptor signaling pathway
0.75	GO:0038095	Fc-epsilon receptor signaling pathway
0.73	GO:0030449	regulation of complement activation
0.70	GO:0050900	leukocyte migration
0.63	GO:0099024	plasma membrane invagination
0.62	GO:0050871	positive regulation of B cell activation
0.62	GO:0006898	receptor-mediated endocytosis

0.85	GO:0003823	antigen binding
0.64	GO:0034987	immunoglobulin receptor binding
0.59	GO:0004252	serine-type endopeptidase activity

0.68	GO:0072562	blood microparticle
0.64	GO:0042571	immunoglobulin complex, circulating
0.60	GO:0009897	external side of plasma membrane
0.54	GO:0070062	extracellular exosome

0.59

GO:0004252

sp|P01785|HV02_CANLF
Ig heavy chain V region MOO
Search

IGHM

0.70	Pterin-mimicking anti-idiotope heavy chain variable region (Fragment)

sp|P01874|IGHM_CANLF
Ig mu chain C region
Search

IGHM

0.93	Immunoglobulin heavy constant mu

0.72	GO:0002250	adaptive immune response
0.71	GO:0006959	humoral immune response
0.69	GO:0045087	innate immune response
0.68	GO:0006910	phagocytosis, recognition
0.68	GO:0042742	defense response to bacterium
0.67	GO:0006911	phagocytosis, engulfment
0.67	GO:0050853	B cell receptor signaling pathway
0.66	GO:0050871	positive regulation of B cell activation
0.66	GO:0002449	lymphocyte mediated immunity
0.65	GO:0072376	protein activation cascade

0.76	GO:0034987	immunoglobulin receptor binding
0.67	GO:0003823	antigen binding
0.66	GO:0031210	phosphatidylcholine binding
0.59	GO:0042834	peptidoglycan binding
0.57	GO:0003697	single-stranded DNA binding

0.76	GO:0042571	immunoglobulin complex, circulating
0.70	GO:0071753	IgM immunoglobulin complex
0.67	GO:0072562	blood microparticle
0.66	GO:0009986	cell surface
0.60	GO:0098552	side of membrane
0.52	GO:0044459	plasma membrane part
0.43	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P02648|APOA1_CANLF
Apolipoprotein A-I
Search

APOA1

0.97	apolipoprotein A-I precursor

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.73	GO:0008203	cholesterol metabolic process
0.72	GO:0030300	regulation of intestinal cholesterol absorption
0.72	GO:0034380	high-density lipoprotein particle assembly
0.72	GO:0010873	positive regulation of cholesterol esterification
0.72	GO:0060354	negative regulation of cell adhesion molecule production
0.71	GO:0018158	protein oxidation
0.70	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
0.70	GO:0034369	plasma lipoprotein particle remodeling

0.73	GO:0070653	high-density lipoprotein particle receptor binding
0.72	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.72	GO:0008289	lipid binding
0.70	GO:0008035	high-density lipoprotein particle binding
0.70	GO:0034191	apolipoprotein A-I receptor binding
0.70	GO:0017127	cholesterol transporter activity
0.69	GO:0045499	chemorepellent activity
0.67	GO:0001540	amyloid-beta binding
0.66	GO:0043178	alcohol binding
0.60	GO:0031072	heat shock protein binding

0.76	GO:0034364	high-density lipoprotein particle
0.67	GO:0034385	triglyceride-rich plasma lipoprotein particle
0.62	GO:0030139	endocytic vesicle
0.58	GO:0031012	extracellular matrix
0.52	GO:0042627	chylomicron
0.51	GO:0072562	blood microparticle
0.42	GO:0034362	low-density lipoprotein particle
0.39	GO:0009986	cell surface
0.38	GO:0070062	extracellular exosome
0.37	GO:0034774	secretory granule lumen

sp|P02677|FIBB_CANLF
Fibrinogen beta chain (Fragment)
Search

0.41	Fibrinogen beta chain (Fragment)

0.82	GO:0007596	blood coagulation
0.77	GO:0043152	induction of bacterial agglutination
0.76	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.75	GO:0001775	cell activation
0.75	GO:0042730	fibrinolysis
0.74	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.74	GO:0045907	positive regulation of vasoconstriction
0.74	GO:2000352	negative regulation of endothelial cell apoptotic process
0.74	GO:0031639	plasminogen activation
0.73	GO:0051258	protein polymerization

0.76	GO:0030674	protein binding, bridging
0.69	GO:0005102	receptor binding
0.68	GO:0050839	cell adhesion molecule binding
0.65	GO:0051087	chaperone binding
0.54	GO:0005198	structural molecule activity

0.83	GO:0005577	fibrinogen complex
0.74	GO:0031091	platelet alpha granule
0.69	GO:0009897	external side of plasma membrane
0.64	GO:0005938	cell cortex
0.60	GO:0005783	endoplasmic reticulum

sp|P02727|GLPA_CANLF
Glycophorin-A
Search

0.76	Glycophorin-A

0.30

GO:0044425

membrane part

sp|P04542|ISK1_CANLF
Serine protease inhibitor Kazal-type 1
Search

SPINK1

0.77	pancreatic secretory trypsin inhibitor

0.54	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:1902572	negative regulation of serine-type peptidase activity
0.49	GO:1900003	regulation of serine-type endopeptidase activity
0.49	GO:0006811	ion transport
0.48	GO:0043113	receptor clustering
0.47	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.47	GO:0055085	transmembrane transport
0.47	GO:0060046	regulation of acrosome reaction
0.41	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.40	GO:0090281	negative regulation of calcium ion import

0.55	GO:0004867	serine-type endopeptidase inhibitor activity
0.49	GO:0005215	transporter activity
0.48	GO:0043236	laminin binding
0.39	GO:0008233	peptidase activity
0.36	GO:0004969	histamine receptor activity
0.36	GO:0002162	dystroglycan binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0005520	insulin-like growth factor binding
0.33	GO:0005198	structural molecule activity

0.48	GO:0005886	plasma membrane
0.44	GO:0001669	acrosomal vesicle
0.43	GO:0044421	extracellular region part
0.34	GO:0043005	neuron projection
0.34	GO:0015629	actin cytoskeleton
0.30	GO:0016021	integral component of membrane

0.39

GO:0008233

sp|P04813|CTR2_CANLF
Chymotrypsinogen 2
Search

0.83	Chymotrypsinogen B

0.61	GO:0006508	proteolysis
0.43	GO:0007586	digestion
0.37	GO:0022617	extracellular matrix disassembly
0.35	GO:0009235	cobalamin metabolic process
0.35	GO:0032094	response to food
0.35	GO:0007584	response to nutrient
0.35	GO:0043434	response to peptide hormone
0.34	GO:0043065	positive regulation of apoptotic process
0.34	GO:0034097	response to cytokine
0.34	GO:0030163	protein catabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0097655	serpin family protein binding

0.40	GO:0005615	extracellular space
0.35	GO:0097180	serine protease inhibitor complex
0.34	GO:0005764	lysosome

0.69

GO:0004252

sp|P05123|KCRM_CANLF
Creatine kinase M-type
Search

CKM

0.95	Brain-subtype creatine kinase

0.57	GO:0016310	phosphorylation
0.56	GO:0046314	phosphocreatine biosynthetic process
0.49	GO:0009408	response to heat
0.35	GO:0006600	creatine metabolic process

0.64	GO:0004111	creatine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.49	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.34	GO:0043209	myelin sheath
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.64	EC:2.7.3.2	GO:0004111
0.64	KEGG:R01881	GO:0004111

sp|P05124|KCRB_CANLF
Creatine kinase B-type
Search

CKB

0.93	Brain-subtype creatine kinase

0.56	GO:0016310	phosphorylation
0.44	GO:0030644	cellular chloride ion homeostasis
0.43	GO:0046314	phosphocreatine biosynthetic process
0.41	GO:0007420	brain development
0.40	GO:0009408	response to heat
0.37	GO:0048857	neural nucleus development
0.35	GO:0006600	creatine metabolic process
0.34	GO:0006754	ATP biosynthetic process

0.61	GO:0004111	creatine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031625	ubiquitin protein ligase binding

0.50	GO:0043209	myelin sheath
0.49	GO:0005615	extracellular space
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.37	GO:0043230	extracellular organelle
0.35	GO:0005634	nucleus
0.35	GO:0031982	vesicle

0.61	EC:2.7.3.2	GO:0004111
0.61	KEGG:R01881	GO:0004111

sp|P06583|AT1B1_CANLF
Sodium/potassium-transporting ATPase subunit beta-1
Search

ATP1B1

0.80	Sodium/potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.61	GO:1903281	positive regulation of calcium:sodium antiporter activity
0.61	GO:1903288	positive regulation of potassium ion import
0.61	GO:1903275	positive regulation of sodium ion export
0.61	GO:1903276	regulation of sodium ion export across plasma membrane
0.60	GO:0055119	relaxation of cardiac muscle
0.60	GO:0006883	cellular sodium ion homeostasis
0.60	GO:0086009	membrane repolarization
0.59	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.58	GO:0005391	sodium:potassium-exchanging ATPase activity
0.58	GO:0051117	ATPase binding
0.56	GO:0008022	protein C-terminus binding
0.55	GO:0001671	ATPase activator activity
0.55	GO:0031402	sodium ion binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0030955	potassium ion binding
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0097367	carbohydrate derivative binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.58	GO:0014704	intercalated disc
0.57	GO:0042383	sarcolemma
0.56	GO:0043209	myelin sheath
0.56	GO:0016323	basolateral plasma membrane
0.55	GO:0016324	apical plasma membrane
0.41	GO:0005901	caveola
0.37	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome

0.58

GO:0005391

sp|P06596|PA21B_CANLF
Phospholipase A2
Search

PLA2G1B

0.68	Phospholipase A2, major isoenzyme

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.55	GO:0002227	innate immune response in mucosa
0.55	GO:0044241	lipid digestion
0.54	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.54	GO:0044243	multicellular organismal catabolic process
0.54	GO:0019731	antibacterial humoral response
0.54	GO:0045740	positive regulation of DNA replication
0.53	GO:0050830	defense response to Gram-positive bacterium

0.82	GO:0004623	phospholipase A2 activity
0.80	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.80	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.70	GO:0005509	calcium ion binding
0.48	GO:0005102	receptor binding
0.42	GO:0090729	toxin activity
0.37	GO:0032052	bile acid binding
0.34	GO:0008061	chitin binding
0.33	GO:0003723	RNA binding

0.66	GO:0005576	extracellular region
0.49	GO:0009986	cell surface
0.46	GO:0005829	cytosol
0.38	GO:0030141	secretory granule
0.30	GO:0016020	membrane

0.82

EC:3.1.1.4

GO:0004623

sp|P06625|SRPRA_CANLF
Signal recognition particle receptor subunit alpha
Search

SRPRA

0.87	Signal recognition particle receptor subunit alpha

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.36	GO:0036498	IRE1-mediated unfolded protein response

0.84	GO:0005047	signal recognition particle binding
0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003723	RNA binding

0.84	GO:0005785	signal recognition particle receptor complex
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P06857|LIPR1_CANLF
Inactive pancreatic lipase-related protein 1
Search

0.58	Pancreatic triacylglycerol lipase

0.68	GO:0016042	lipid catabolic process
0.57	GO:0007586	digestion
0.54	GO:0061365	positive regulation of triglyceride lipase activity
0.51	GO:0030301	cholesterol transport
0.49	GO:0006968	cellular defense response
0.47	GO:0003008	system process
0.36	GO:0042750	hibernation
0.35	GO:0001523	retinoid metabolic process
0.34	GO:0043434	response to peptide hormone
0.34	GO:0009791	post-embryonic development

0.77	GO:0004806	triglyceride lipase activity
0.36	GO:0046872	metal ion binding

0.65

GO:0005576

extracellular region

0.77

EC:3.1.1.3

GO:0004806

sp|P06871|TRY1_CANLF
Cationic trypsin
Search

0.47	Cationic trypsinogen

0.61	GO:0006508	proteolysis
0.51	GO:0007586	digestion
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.38	GO:0030574	collagen catabolic process
0.38	GO:0035094	response to nicotine
0.35	GO:0022617	extracellular matrix disassembly
0.34	GO:0043542	endothelial cell migration
0.33	GO:0051604	protein maturation
0.33	GO:0009235	cobalamin metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0005509	calcium ion binding
0.35	GO:0097655	serpin family protein binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0097180	serine protease inhibitor complex
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P06872|TRY2_CANLF
Anionic trypsin
Search

0.46	Pancreatic anionic trypsinogen

0.61	GO:0006508	proteolysis
0.52	GO:0007586	digestion
0.40	GO:0030574	collagen catabolic process
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.38	GO:0035094	response to nicotine
0.36	GO:0043542	endothelial cell migration
0.35	GO:0022617	extracellular matrix disassembly
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0019730	antimicrobial humoral response

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity

0.51	GO:0005615	extracellular space
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005766	primary lysosome
0.35	GO:0005775	vacuolar lumen
0.34	GO:0031012	extracellular matrix
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P06908|SFTPA_CANLF
Pulmonary surfactant-associated protein A
Search

SFTPA1

0.91	Pulmonary surfactant-associated protein A

0.62	GO:0007585	respiratory gaseous exchange
0.53	GO:0008228	opsonization
0.46	GO:0002253	activation of immune response
0.44	GO:0033189	response to vitamin A
0.44	GO:0071732	cellular response to nitric oxide
0.43	GO:0055093	response to hyperoxia
0.43	GO:0070741	response to interleukin-6
0.43	GO:0070849	response to epidermal growth factor
0.43	GO:0050766	positive regulation of phagocytosis
0.43	GO:0071260	cellular response to mechanical stimulus

0.54	GO:0030246	carbohydrate binding
0.48	GO:0005201	extracellular matrix structural constituent
0.43	GO:0046872	metal ion binding
0.42	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0005319	lipid transporter activity
0.38	GO:0005515	protein binding
0.36	GO:0004478	methionine adenosyltransferase activity
0.36	GO:0036094	small molecule binding
0.35	GO:0042302	structural constituent of cuticle
0.33	GO:0044877	macromolecular complex binding

0.74	GO:0005581	collagen trimer
0.60	GO:0005578	proteinaceous extracellular matrix
0.55	GO:0005615	extracellular space
0.48	GO:0044420	extracellular matrix component
0.44	GO:0042599	lamellar body
0.43	GO:0005783	endoplasmic reticulum
0.43	GO:0005771	multivesicular body
0.43	GO:0045334	clathrin-coated endocytic vesicle
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment

0.36

EC:2.5.1.6

GO:0004478

sp|P07499|ANF_CANLF
Natriuretic peptides A
Search

NPPA

0.97	Atrial natriuretic peptide hormone

0.76	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.68	GO:0007168	receptor guanylyl cyclase signaling pathway
0.67	GO:1903766	positive regulation of potassium ion export across plasma membrane
0.66	GO:1902261	positive regulation of delayed rectifier potassium channel activity
0.66	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization
0.65	GO:0060452	positive regulation of cardiac muscle contraction
0.64	GO:0010460	positive regulation of heart rate
0.63	GO:0007565	female pregnancy
0.63	GO:0008217	regulation of blood pressure

0.79	GO:0005179	hormone activity
0.63	GO:0071855	neuropeptide receptor binding
0.60	GO:0051427	hormone receptor binding

0.66	GO:0005576	extracellular region
0.47	GO:0043234	protein complex
0.42	GO:0042629	mast cell granule
0.40	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P08989|GRP_CANLF
Gastrin-releasing peptide
Search

GRP

0.72	Gastrin-releasing peptide

0.80	GO:0007218	neuropeptide signaling pathway
0.72	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
0.72	GO:0010469	regulation of receptor activity
0.68	GO:0036343	psychomotor behavior
0.64	GO:0035176	social behavior
0.54	GO:0043207	response to external biotic stimulus
0.51	GO:0090277	positive regulation of peptide hormone secretion
0.38	GO:0048565	digestive tract development

0.81

GO:0005184

neuropeptide hormone activity

0.60	GO:0005615	extracellular space
0.52	GO:0034774	secretory granule lumen
0.38	GO:0070852	cell body fiber
0.36	GO:0044297	cell body

sp|P09582|ESTA_CANLF
Arginine esterase
Search

0.96	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.41	GO:0002778	antibacterial peptide production
0.38	GO:0009405	pathogenesis
0.38	GO:0048584	positive regulation of response to stimulus
0.38	GO:0051604	protein maturation
0.37	GO:0032101	regulation of response to external stimulus
0.37	GO:0008015	blood circulation
0.37	GO:0072376	protein activation cascade
0.36	GO:0007584	response to nutrient
0.36	GO:0031347	regulation of defense response

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.39	GO:0090729	toxin activity
0.36	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0008083	growth factor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004222	metalloendopeptidase activity

0.47	GO:0005576	extracellular region
0.40	GO:0043234	protein complex
0.38	GO:0031982	vesicle
0.37	GO:0005634	nucleus
0.36	GO:0097223	sperm part
0.36	GO:0045177	apical part of cell
0.36	GO:0012505	endomembrane system
0.34	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P09910|SECR_CANLF
Secretin
Search

SCT

0.46

Secretin

0.76	GO:0010469	regulation of receptor activity
0.51	GO:1903640	negative regulation of gastrin-induced gastric acid secretion
0.50	GO:0090274	positive regulation of somatostatin secretion
0.50	GO:0090187	positive regulation of pancreatic juice secretion
0.48	GO:0043950	positive regulation of cAMP-mediated signaling
0.48	GO:0007420	brain development
0.47	GO:0097150	neuronal stem cell population maintenance
0.47	GO:0048566	embryonic digestive tract development
0.47	GO:0008542	visual learning
0.46	GO:0043524	negative regulation of neuron apoptotic process

0.79	GO:0005179	hormone activity
0.47	GO:0047485	protein N-terminus binding

0.66

GO:0005576

extracellular region

sp|P0C5H0|GLOD5_CANLF
Glyoxalase domain-containing protein 5
Search

GLOD5

0.47	Glyoxalase domain-containing protein 5

0.48	GO:0055114	oxidation-reduction process
0.34	GO:0071897	DNA biosynthetic process
0.34	GO:0019439	aromatic compound catabolic process
0.34	GO:0006260	DNA replication

0.62	GO:0051213	dioxygenase activity
0.53	GO:0004462	lactoylglutathione lyase activity
0.41	GO:0046872	metal ion binding
0.35	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0003677	DNA binding
0.33	GO:0016787	hydrolase activity

0.53	EC:4.4.1.5	GO:0004462
0.53	KEGG:R02530	GO:0004462

sp|P0C8R9|ECSCR_CANLF
Endothelial cell-specific chemotaxis regulator
Search

ECSCR

0.97	Endothelial cell surface-expressed chemotaxis and apoptosis regulator

0.53	GO:0016525	negative regulation of angiogenesis
0.51	GO:0001525	angiogenesis
0.49	GO:2000353	positive regulation of endothelial cell apoptotic process
0.49	GO:0006915	apoptotic process
0.47	GO:0030154	cell differentiation
0.46	GO:0006935	chemotaxis
0.46	GO:1901800	positive regulation of proteasomal protein catabolic process

0.36

GO:0005515

protein binding

0.46	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.41	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|P0CAN6|CD79A_CANLF
B-cell antigen receptor complex-associated protein alpha chain
Search

CD79A

0.97	B-cell antigen receptor complex-associated protein alpha chain

0.69	GO:0007166	cell surface receptor signaling pathway
0.68	GO:0051289	protein homotetramerization
0.66	GO:0030183	B cell differentiation
0.66	GO:0042100	B cell proliferation
0.63	GO:0002757	immune response-activating signal transduction
0.45	GO:0002250	adaptive immune response
0.37	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0065009	regulation of molecular function
0.34	GO:0006518	peptide metabolic process
0.34	GO:0043604	amide biosynthetic process

0.68	GO:0004888	transmembrane signaling receptor activity
0.61	GO:0042803	protein homodimerization activity
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0046872	metal ion binding

0.70	GO:0019815	B cell receptor complex
0.65	GO:0005771	multivesicular body
0.63	GO:0009897	external side of plasma membrane
0.61	GO:0045121	membrane raft
0.46	GO:0005887	integral component of plasma membrane
0.34	GO:0005840	ribosome
0.34	GO:0005634	nucleus

sp|P10463|CAYP1_CANLF
Calcyphosin
Search

CAPS

0.95	Calcyphosine like

0.33	GO:0035556	intracellular signal transduction
0.32	GO:0016310	phosphorylation

0.70	GO:0005509	calcium ion binding
0.32	GO:0016301	kinase activity

0.35	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

sp|P10673|NEUT_CANLF
Neurotensin/neuromedin N
Search

NTS

0.97	Neurotensin/neuromedin N

0.76	GO:0010469	regulation of receptor activity
0.43	GO:0050880	regulation of blood vessel size
0.37	GO:0097332	response to antipsychotic drug
0.37	GO:0051412	response to corticosterone
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0071285	cellular response to lithium ion
0.37	GO:0071549	cellular response to dexamethasone stimulus
0.37	GO:0001975	response to amphetamine
0.37	GO:1990090	cellular response to nerve growth factor stimulus
0.36	GO:0042220	response to cocaine

0.85

GO:0005184

neuropeptide hormone activity

0.66	GO:0005576	extracellular region
0.51	GO:0043679	axon terminus
0.42	GO:0030133	transport vesicle
0.36	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|P11613|ACKR3_CANLF
Atypical chemokine receptor 3
Search

ACKR3

0.97	C-X-C chemokine receptor type 7

0.83	GO:0001570	vasculogenesis
0.79	GO:0001525	angiogenesis
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0006935	chemotaxis
0.60	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.59	GO:0031623	receptor internalization
0.59	GO:0070098	chemokine-mediated signaling pathway
0.57	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.46	GO:0048920	posterior lateral line neuromast primordium migration
0.41	GO:1905320	regulation of mesenchymal stem cell migration

0.85	GO:0019956	chemokine binding
0.84	GO:0015026	coreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.58	GO:0004896	cytokine receptor activity
0.56	GO:0001653	peptide receptor activity
0.56	GO:0005044	scavenger receptor activity
0.35	GO:0016502	nucleotide receptor activity
0.35	GO:0035586	purinergic receptor activity
0.34	GO:0008289	lipid binding
0.33	GO:0042277	peptide binding

0.56	GO:0005905	clathrin-coated pit
0.53	GO:0005768	endosome
0.53	GO:0009986	cell surface
0.43	GO:0005886	plasma membrane
0.43	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0043005	neuron projection
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P11614|5HT1D_CANLF
5-hydroxytryptamine receptor 1D
Search

HTR1D

0.97	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled

0.85	GO:0042310	vasoconstriction
0.85	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.84	GO:0050795	regulation of behavior
0.78	GO:0007268	chemical synaptic transmission
0.76	GO:0006939	smooth muscle contraction
0.69	GO:0040012	regulation of locomotion
0.63	GO:0046849	bone remodeling
0.62	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.62	GO:0007631	feeding behavior
0.51	GO:0014063	negative regulation of serotonin secretion

0.85	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.61	GO:0051378	serotonin binding
0.37	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.36	GO:0005737	cytoplasm

sp|P11615|ADA1B_CANLF
Alpha-1B adrenergic receptor (Fragment)
Search

ADRA1B

0.95	Melanopsin

0.85	GO:0071875	adrenergic receptor signaling pathway
0.84	GO:0055117	regulation of cardiac muscle contraction
0.83	GO:0019229	regulation of vasoconstriction
0.55	GO:0043410	positive regulation of MAPK cascade
0.52	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
0.50	GO:0045987	positive regulation of smooth muscle contraction
0.50	GO:1903524	positive regulation of blood circulation
0.49	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.49	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.48	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.86	GO:0004937	alpha1-adrenergic receptor activity
0.52	GO:0046982	protein heterodimerization activity

0.55	GO:0031965	nuclear membrane
0.55	GO:0005886	plasma membrane
0.40	GO:0045121	membrane raft
0.40	GO:0005737	cytoplasm
0.35	GO:0014704	intercalated disc
0.30	GO:0016021	integral component of membrane

sp|P11616|AA1R_CANLF
Adenosine receptor A1
Search

ADORA1

0.97	Adenosine receptor A1

0.85	GO:0001973	adenosine receptor signaling pathway
0.61	GO:0070256	negative regulation of mucus secretion
0.61	GO:1900453	negative regulation of long term synaptic depression
0.60	GO:0003093	regulation of glomerular filtration
0.59	GO:0051930	regulation of sensory perception of pain
0.58	GO:0002686	negative regulation of leukocyte migration
0.57	GO:0050728	negative regulation of inflammatory response
0.54	GO:0060079	excitatory postsynaptic potential
0.41	GO:0097756	negative regulation of blood vessel diameter
0.41	GO:0032242	regulation of nucleoside transport

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.40	GO:0032795	heterotrimeric G-protein binding
0.38	GO:0031683	G-protein beta/gamma-subunit complex binding
0.38	GO:0001664	G-protein coupled receptor binding
0.38	GO:0004629	phospholipase C activity
0.37	GO:0031072	heat shock protein binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0001883	purine nucleoside binding

0.57	GO:0043197	dendritic spine
0.55	GO:0005886	plasma membrane
0.39	GO:0043195	terminal bouton
0.38	GO:0044304	main axon
0.38	GO:0014069	postsynaptic density
0.38	GO:0048786	presynaptic active zone
0.38	GO:0043025	neuronal cell body
0.38	GO:0031252	cell leading edge
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|P11617|AA2AR_CANLF
Adenosine receptor A2a
Search

ADORA2A

0.95	Adenosine receptor A2

0.85	GO:0001973	adenosine receptor signaling pathway
0.59	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.59	GO:0060080	inhibitory postsynaptic potential
0.58	GO:0001963	synaptic transmission, dopaminergic
0.58	GO:0001975	response to amphetamine
0.58	GO:0042755	eating behavior
0.58	GO:0046636	negative regulation of alpha-beta T cell activation
0.57	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.56	GO:0050728	negative regulation of inflammatory response
0.55	GO:2001235	positive regulation of apoptotic signaling pathway

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.51	GO:0042802	identical protein binding
0.50	GO:0019899	enzyme binding
0.42	GO:0031802	type 5 metabotropic glutamate receptor binding
0.41	GO:0051393	alpha-actinin binding
0.38	GO:0046982	protein heterodimerization activity
0.34	GO:0016519	gastric inhibitory peptide receptor activity

0.55	GO:0005886	plasma membrane
0.52	GO:0098794	postsynapse
0.40	GO:0044304	main axon
0.40	GO:0032279	asymmetric synapse
0.40	GO:0048786	presynaptic active zone
0.40	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.39	GO:0031252	cell leading edge
0.39	GO:0005882	intermediate filament
0.37	GO:0012505	endomembrane system

sp|P12064|EDN2_CANLF
Endothelin-2
Search

EDN2

0.96	Endothelin-2

0.85	GO:0019229	regulation of vasoconstriction
0.79	GO:0042310	vasoconstriction
0.68	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity
0.67	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.67	GO:0014820	tonic smooth muscle contraction
0.66	GO:0014821	phasic smooth muscle contraction
0.66	GO:0010460	positive regulation of heart rate
0.64	GO:0046457	prostanoid biosynthetic process
0.64	GO:0006693	prostaglandin metabolic process
0.63	GO:0051353	positive regulation of oxidoreductase activity

0.68	GO:0031708	endothelin B receptor binding
0.59	GO:0005179	hormone activity
0.49	GO:0031707	endothelin A receptor binding
0.44	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.39	GO:0005622	intracellular
0.37	GO:0045178	basal part of cell
0.36	GO:0031982	vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

0.63

EC:1.97.1

GO:0051353

sp|P12278|APOC2_CANLF
Apolipoprotein C-II
Search

APOC2

0.97	Apolipoprotein C-II

0.74	GO:0006869	lipid transport
0.73	GO:0043085	positive regulation of catalytic activity
0.67	GO:0060697	positive regulation of phospholipid catabolic process
0.66	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.66	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.65	GO:0034384	high-density lipoprotein particle clearance
0.65	GO:0010985	negative regulation of lipoprotein particle clearance
0.64	GO:0032375	negative regulation of cholesterol transport
0.64	GO:0048261	negative regulation of receptor-mediated endocytosis
0.64	GO:0051004	regulation of lipoprotein lipase activity

0.75	GO:0008047	enzyme activator activity
0.65	GO:0043274	phospholipase binding
0.63	GO:0055102	lipase inhibitor activity
0.56	GO:0042803	protein homodimerization activity
0.54	GO:0008289	lipid binding

0.86	GO:0042627	chylomicron
0.78	GO:0034362	low-density lipoprotein particle
0.75	GO:0034361	very-low-density lipoprotein particle
0.75	GO:0034364	high-density lipoprotein particle
0.65	GO:0034363	intermediate-density lipoprotein particle
0.41	GO:0070062	extracellular exosome
0.38	GO:0005769	early endosome
0.36	GO:0005829	cytosol

sp|P12279|APOC3_CANLF
Apolipoprotein C-III
Search

APOC3

0.97	Apolipoprotein C-III

0.80	GO:0010987	negative regulation of high-density lipoprotein particle clearance
0.79	GO:0010897	negative regulation of triglyceride catabolic process
0.79	GO:0010989	negative regulation of low-density lipoprotein particle clearance
0.79	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.78	GO:0051005	negative regulation of lipoprotein lipase activity
0.77	GO:0060621	negative regulation of cholesterol import
0.77	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
0.76	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.75	GO:0042157	lipoprotein metabolic process
0.75	GO:0032489	regulation of Cdc42 protein signal transduction

0.79	GO:0070653	high-density lipoprotein particle receptor binding
0.74	GO:0055102	lipase inhibitor activity
0.72	GO:0008289	lipid binding
0.47	GO:0043168	anion binding
0.38	GO:0043178	alcohol binding
0.33	GO:0097159	organic cyclic compound binding

0.77	GO:0034363	intermediate-density lipoprotein particle
0.77	GO:0034366	spherical high-density lipoprotein particle
0.76	GO:0042627	chylomicron
0.76	GO:0034361	very-low-density lipoprotein particle
0.62	GO:0031012	extracellular matrix
0.38	GO:0070062	extracellular exosome
0.38	GO:0005769	early endosome
0.36	GO:0005829	cytosol

sp|P12637|CASQ2_CANLF
Calsequestrin-2
Search

CASQ2

0.91	Calsequestrin

0.58	GO:0051208	sequestering of calcium ion
0.58	GO:0071313	cellular response to caffeine
0.58	GO:0010649	regulation of cell communication by electrical coupling
0.58	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.58	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.57	GO:1901017	negative regulation of potassium ion transmembrane transporter activity
0.56	GO:0060306	regulation of membrane repolarization
0.55	GO:0060048	cardiac muscle contraction
0.55	GO:0002027	regulation of heart rate
0.55	GO:0045214	sarcomere organization

0.70	GO:0005509	calcium ion binding
0.56	GO:0048306	calcium-dependent protein binding
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0005080	protein kinase C binding
0.32	GO:0016887	ATPase activity
0.32	GO:0005524	ATP binding

0.60	GO:0033018	sarcoplasmic reticulum lumen
0.57	GO:0030314	junctional membrane complex
0.54	GO:0030018	Z disc
0.42	GO:0014802	terminal cisterna
0.36	GO:0005891	voltage-gated calcium channel complex
0.36	GO:0014701	junctional sarcoplasmic reticulum membrane

0.32

GO:0016887

sp|P12800|FIBG_CANLF
Fibrinogen gamma chain (Fragment)
Search

0.61	Fibrinogen gamma chain (Fragment)

0.85	GO:0030168	platelet activation
0.77	GO:0051258	protein polymerization
0.68	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.67	GO:0072378	blood coagulation, fibrin clot formation
0.67	GO:0042730	fibrinolysis
0.66	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.66	GO:0045907	positive regulation of vasoconstriction
0.66	GO:2000352	negative regulation of endothelial cell apoptotic process
0.66	GO:0031639	plasminogen activation
0.66	GO:0034109	homotypic cell-cell adhesion

0.80	GO:0030674	protein binding, bridging
0.72	GO:0005102	receptor binding
0.61	GO:0050839	cell adhesion molecule binding
0.50	GO:0005198	structural molecule activity
0.40	GO:0042803	protein homodimerization activity
0.37	GO:0046872	metal ion binding

0.86	GO:0005577	fibrinogen complex
0.66	GO:0031091	platelet alpha granule
0.62	GO:0009897	external side of plasma membrane
0.42	GO:0072562	blood microparticle
0.39	GO:0070062	extracellular exosome
0.38	GO:0005938	cell cortex
0.37	GO:0034774	secretory granule lumen
0.37	GO:0005788	endoplasmic reticulum lumen

sp|P13206|EDN1_CANLF
Endothelin-1
Search

EDN1

0.95	Preproendothelin

0.85	GO:0019229	regulation of vasoconstriction
0.69	GO:0042310	vasoconstriction
0.68	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity
0.67	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.67	GO:0014820	tonic smooth muscle contraction
0.65	GO:0014821	phasic smooth muscle contraction
0.65	GO:0010460	positive regulation of heart rate
0.65	GO:0042313	protein kinase C deactivation
0.64	GO:0030185	nitric oxide transport
0.64	GO:0046457	prostanoid biosynthetic process

0.68	GO:0031708	endothelin B receptor binding
0.66	GO:0031707	endothelin A receptor binding
0.59	GO:0005179	hormone activity
0.57	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.44	GO:0048237	rough endoplasmic reticulum lumen
0.43	GO:0033093	Weibel-Palade body
0.42	GO:0045178	basal part of cell
0.35	GO:0030133	transport vesicle

0.63

EC:1.97.1

GO:0051353

sp|P13679|SC11C_CANLF
Signal peptidase complex catalytic subunit SEC11C
Search

SEC11C

0.72	Signal peptidase complex catalytic subunit SEC11

0.79

GO:0006465

signal peptide processing

0.67

GO:0008236

serine-type peptidase activity

0.82	GO:0005787	signal peptidase complex
0.38	GO:0031090	organelle membrane
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P14763|TSHR_CANLF
Thyrotropin receptor
Search

TSHR

0.95	Thyrotropin receptor

0.86	GO:0038194	thyroid-stimulating hormone signaling pathway
0.59	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.57	GO:0090103	cochlea morphogenesis
0.57	GO:0071542	dopaminergic neuron differentiation
0.56	GO:0060122	inner ear receptor cell stereocilium organization
0.56	GO:0040018	positive regulation of multicellular organism growth
0.56	GO:0030183	B cell differentiation
0.55	GO:0008344	adult locomotory behavior
0.52	GO:0040012	regulation of locomotion
0.51	GO:0007190	activation of adenylate cyclase activity

0.86	GO:0004996	thyroid-stimulating hormone receptor activity
0.48	GO:0008528	G-protein coupled peptide receptor activity
0.42	GO:0032403	protein complex binding

0.54	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.38	GO:0043235	receptor complex
0.35	GO:0045121	membrane raft
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P15881|ITF2_CANLF
Transcription factor 4
Search

TCF4

0.92	Transcription factor 4

0.51	GO:0045666	positive regulation of neuron differentiation
0.50	GO:0042118	endothelial cell activation
0.50	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.48	GO:0016525	negative regulation of angiogenesis
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0006367	transcription initiation from RNA polymerase II promoter
0.46	GO:0065004	protein-DNA complex assembly
0.46	GO:0000122	negative regulation of transcription by RNA polymerase II

0.66	GO:0046983	protein dimerization activity
0.53	GO:0001087	transcription factor activity, TFIIB-class binding
0.53	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting
0.52	GO:0001093	TFIIB-class transcription factor binding
0.51	GO:0070888	E-box binding
0.49	GO:0043621	protein self-association
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0003714	transcription corepressor activity
0.47	GO:0043425	bHLH transcription factor binding
0.46	GO:0003682	chromatin binding

0.48	GO:0005667	transcription factor complex
0.43	GO:0005634	nucleus
0.36	GO:0000785	chromatin
0.36	GO:0043233	organelle lumen
0.34	GO:0032993	protein-DNA complex
0.30	GO:0016021	integral component of membrane

sp|P15944|TRYT_CANLF
Tryptase
Search

0.79	Mast cell tryptase beta III

0.61	GO:0006508	proteolysis
0.41	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.41	GO:0060672	epithelial cell morphogenesis involved in placental branching
0.40	GO:0030216	keratinocyte differentiation
0.39	GO:0001843	neural tube closure
0.38	GO:0050878	regulation of body fluid levels
0.37	GO:0022617	extracellular matrix disassembly
0.37	GO:0050819	negative regulation of coagulation
0.37	GO:0061045	negative regulation of wound healing
0.37	GO:0050817	coagulation

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0008201	heparin binding
0.35	GO:0005515	protein binding
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0017080	sodium channel regulator activity

0.45	GO:0005576	extracellular region
0.38	GO:0019897	extrinsic component of plasma membrane
0.37	GO:0042629	mast cell granule
0.35	GO:0016323	basolateral plasma membrane
0.34	GO:0031225	anchored component of membrane
0.33	GO:0031226	intrinsic component of plasma membrane
0.32	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P16255|SRP14_CANLF
Signal recognition particle 14 kDa protein
Search

SRP14

0.44	Signal recognition particle 14

0.72	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.46	GO:0042493	response to drug
0.35	GO:0043312	neutrophil degranulation

0.81	GO:0030942	endoplasmic reticulum signal peptide binding
0.75	GO:0008312	7S RNA binding
0.35	GO:0050825	ice binding
0.33	GO:0005515	protein binding

0.78	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.43	GO:0005634	nucleus
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P16859|ANFB_CANLF
Natriuretic peptides B
Search

NPPB

0.94	B-type natriuretic peptide

0.81	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.63	GO:0007168	receptor guanylyl cyclase signaling pathway
0.59	GO:0006182	cGMP biosynthetic process
0.47	GO:0006457	protein folding
0.38	GO:0035815	positive regulation of renal sodium excretion
0.38	GO:0035810	positive regulation of urine volume
0.38	GO:0043114	regulation of vascular permeability
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0007589	body fluid secretion

0.79	GO:0005179	hormone activity
0.54	GO:0051427	hormone receptor binding

0.66	GO:0005576	extracellular region
0.43	GO:0043234	protein complex

sp|P16967|SSRA_CANLF
Translocon-associated protein subunit alpha
Search

SSR1

0.83	Translocon-associated protein subunit alpha

0.44	GO:0006613	cotranslational protein targeting to membrane
0.43	GO:0071391	cellular response to estrogen stimulus
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0008284	positive regulation of cell proliferation

0.33

GO:0005515

protein binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P17124|HRH2_CANLF
Histamine H2 receptor
Search

HRH2

0.97	Histamine H2 receptor

0.83	GO:0001696	gastric acid secretion
0.81	GO:0045907	positive regulation of vasoconstriction
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0008542	visual learning
0.54	GO:0003382	epithelial cell morphogenesis
0.53	GO:0007613	memory
0.53	GO:0048167	regulation of synaptic plasticity
0.52	GO:0048565	digestive tract development
0.51	GO:0048732	gland development
0.51	GO:1901998	toxin transport

0.81	GO:0004969	histamine receptor activity
0.45	GO:0004952	dopamine neurotransmitter receptor activity
0.38	GO:0099589	serotonin receptor activity
0.35	GO:0051378	serotonin binding
0.35	GO:0004935	adrenergic receptor activity
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.33	GO:0009881	photoreceptor activity
0.33	GO:0001609	G-protein coupled adenosine receptor activity
0.33	GO:0004983	neuropeptide Y receptor activity

0.41

GO:0005887

integral component of plasma membrane

0.34

EC:2.7.10.2

GO:0004715

sp|P17129|PSPB_CANLF
Pulmonary surfactant-associated protein B (Fragment)
Search

SFTPB

0.96	Pulmonary surfactant-associated protein B

0.70	GO:0006665	sphingolipid metabolic process
0.59	GO:0007585	respiratory gaseous exchange
0.52	GO:0009887	animal organ morphogenesis
0.50	GO:0043085	positive regulation of catalytic activity
0.43	GO:0050828	regulation of liquid surface tension
0.42	GO:0033189	response to vitamin A
0.42	GO:0071732	cellular response to nitric oxide
0.42	GO:0055093	response to hyperoxia
0.42	GO:0070741	response to interleukin-6
0.41	GO:0070849	response to epidermal growth factor

0.53	GO:0001664	G-protein coupled receptor binding
0.51	GO:0008047	enzyme activator activity

0.70	GO:0005764	lysosome
0.59	GO:0097208	alveolar lamellar body
0.56	GO:0005771	multivesicular body
0.52	GO:0005615	extracellular space
0.44	GO:0031906	late endosome lumen
0.41	GO:0045334	clathrin-coated endocytic vesicle
0.38	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005654	nucleoplasm

sp|P17716|IAPP_CANLF
Islet amyloid polypeptide
Search

IAPP

0.94	islet amyloid polypeptide precursor

0.76	GO:0010469	regulation of receptor activity
0.66	GO:0045779	negative regulation of bone resorption
0.63	GO:0019233	sensory perception of pain
0.59	GO:0045596	negative regulation of cell differentiation
0.46	GO:0097647	amylin receptor signaling pathway
0.45	GO:0042755	eating behavior
0.40	GO:0030816	positive regulation of cAMP metabolic process
0.38	GO:1905907	negative regulation of amyloid fibril formation
0.38	GO:1900019	regulation of protein kinase C activity
0.38	GO:1990000	amyloid fibril formation

0.79	GO:0005179	hormone activity
0.55	GO:0042802	identical protein binding
0.37	GO:0001540	amyloid-beta binding

0.66	GO:0005576	extracellular region
0.60	GO:0043025	neuronal cell body
0.37	GO:0016234	inclusion body
0.36	GO:0030141	secretory granule
0.35	GO:0005829	cytosol

sp|P18066|RAB5A_CANLF
Ras-related protein Rab-5A
Search

RAB5A

0.88	Putative rab subfamily protein of small gtpase

0.54	GO:0051489	regulation of filopodium assembly
0.53	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway
0.52	GO:0060627	regulation of vesicle-mediated transport
0.52	GO:0051036	regulation of endosome size
0.51	GO:0045056	transcytosis
0.51	GO:0045022	early endosome to late endosome transport
0.51	GO:0098693	regulation of synaptic vesicle cycle
0.50	GO:0046928	regulation of neurotransmitter secretion
0.50	GO:0036465	synaptic vesicle recycling
0.49	GO:1903532	positive regulation of secretion by cell

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.51	GO:0019003	GDP binding
0.35	GO:0051021	GDP-dissociation inhibitor binding
0.34	GO:0004402	histone acetyltransferase activity
0.32	GO:0046872	metal ion binding

0.54	GO:0005769	early endosome
0.54	GO:0030139	endocytic vesicle
0.52	GO:0001726	ruffle
0.51	GO:0010009	cytoplasmic side of endosome membrane
0.50	GO:0098857	membrane microdomain
0.50	GO:0043195	terminal bouton
0.48	GO:0036477	somatodendritic compartment
0.48	GO:0015629	actin cytoskeleton
0.44	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane

0.34

EC:2.3.1.48

GO:0004402

sp|P18067|RAB7A_CANLF
Ras-related protein Rab-7a
Search

RAB7A

0.94	RAB7A, member RAS oncogene family

0.58	GO:0061724	lipophagy
0.57	GO:0007174	epidermal growth factor catabolic process
0.56	GO:0090383	phagosome acidification
0.56	GO:0090385	phagosome-lysosome fusion
0.56	GO:1903542	negative regulation of exosomal secretion
0.55	GO:0022615	protein to membrane docking
0.55	GO:0045022	early endosome to late endosome transport
0.54	GO:1903543	positive regulation of exosomal secretion
0.54	GO:0006622	protein targeting to lysosome
0.53	GO:0008333	endosome to lysosome transport

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.56	GO:1905394	retromer complex binding
0.53	GO:0019003	GDP binding
0.40	GO:0048365	Rac GTPase binding

0.57	GO:0032419	extrinsic component of lysosome membrane
0.55	GO:0005770	late endosome
0.53	GO:0045335	phagocytic vesicle
0.52	GO:0005811	lipid droplet
0.52	GO:0034045	phagophore assembly site membrane
0.51	GO:0010008	endosome membrane
0.51	GO:0030904	retromer complex
0.47	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.42	GO:0033162	melanosome membrane

sp|P18174|INVO_CANLF
Involucrin
Search

IVL

0.81	Involucrin

0.82	GO:0030216	keratinocyte differentiation
0.54	GO:0010224	response to UV-B
0.53	GO:0018149	peptide cross-linking
0.38	GO:0018199	peptidyl-glutamine modification
0.37	GO:0012501	programmed cell death
0.37	GO:0018205	peptidyl-lysine modification
0.34	GO:0043087	regulation of GTPase activity
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007165	signal transduction
0.34	GO:1902476	chloride transmembrane transport

0.52	GO:0030674	protein binding, bridging
0.44	GO:0005198	structural molecule activity
0.34	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0005254	chloride channel activity
0.34	GO:0046872	metal ion binding
0.34	GO:0009982	pseudouridine synthase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding

0.73	GO:0001533	cornified envelope
0.45	GO:0005737	cytoplasm
0.41	GO:0005813	centrosome
0.41	GO:0016604	nuclear body
0.38	GO:0070062	extracellular exosome
0.36	GO:0032777	Piccolo NuA4 histone acetyltransferase complex
0.35	GO:0031213	RSF complex
0.34	GO:0034707	chloride channel complex
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.34

GO:0000179

sp|P18466|HA19_CANLF
DLA class I histocompatibility antigen, A9/A9 alpha chain
Search

0.40	DLA class I molecule

0.81	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.72	GO:0006955	immune response

0.45	GO:0042605	peptide antigen binding
0.41	GO:0005102	receptor binding

0.80	GO:0042612	MHC class I protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P18470|HB2D_CANLF
DLA class II histocompatibility antigen, DR-1 beta chain
Search

0.44	Leukocyte antigen

0.83	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.74	GO:0006955	immune response

0.76	GO:0042613	MHC class II protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P18649|APOE_CANLF
Apolipoprotein E
Search

APOE

0.97	Apolipoprotein E

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.70	GO:1903000	regulation of lipid transport across blood brain barrier
0.70	GO:1905860	positive regulation of heparan sulfate proteoglycan binding
0.70	GO:1905890	regulation of cellular response to very-low-density lipoprotein particle stimulus
0.70	GO:1901630	negative regulation of presynaptic membrane organization
0.70	GO:1905853	regulation of heparan sulfate binding
0.70	GO:0034372	very-low-density lipoprotein particle remodeling
0.70	GO:1902994	regulation of phospholipid efflux
0.70	GO:0010873	positive regulation of cholesterol esterification

0.73	GO:0008201	heparin binding
0.72	GO:0008289	lipid binding
0.70	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.70	GO:0070326	very-low-density lipoprotein particle receptor binding
0.70	GO:0046911	metal chelating activity
0.69	GO:0001540	amyloid-beta binding
0.68	GO:0048156	tau protein binding
0.67	GO:0050750	low-density lipoprotein particle receptor binding
0.67	GO:0017127	cholesterol transporter activity
0.66	GO:0071813	lipoprotein particle binding

0.77	GO:0042627	chylomicron
0.77	GO:0034361	very-low-density lipoprotein particle
0.76	GO:0034364	high-density lipoprotein particle
0.70	GO:0034363	intermediate-density lipoprotein particle
0.68	GO:0034362	low-density lipoprotein particle
0.66	GO:0106003	amyloid-beta complex
0.57	GO:0031012	extracellular matrix
0.55	GO:0005794	Golgi apparatus
0.54	GO:0005783	endoplasmic reticulum
0.47	GO:0072562	blood microparticle

sp|P18651|FGF1_CANLF
Fibroblast growth factor 1 (Fragment)
Search

0.10	Fibroblast growth factor 1 (Fragment)

0.30	GO:0061333	renal tubule morphogenesis
0.30	GO:0001525	angiogenesis
0.30	GO:0045893	positive regulation of transcription, DNA-templated
0.30	GO:0051272	positive regulation of cellular component movement
0.30	GO:0001657	ureteric bud development
0.30	GO:0040012	regulation of locomotion
0.30	GO:0042221	response to chemical
0.30	GO:0009987	cellular process
0.30	GO:0009967	positive regulation of signal transduction
0.30	GO:0010893	positive regulation of steroid biosynthetic process

0.30	GO:0050839	cell adhesion molecule binding
0.30	GO:0098772	molecular function regulator
0.30	GO:1901681	sulfur compound binding
0.30	GO:0032403	protein complex binding
0.30	GO:0043167	ion binding
0.30	GO:0097367	carbohydrate derivative binding
0.30	GO:0044548	S100 protein binding
0.30	GO:0005102	receptor binding

0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0044464	cell part
0.30	GO:0005576	extracellular region

sp|P18842|LSHB_CANLF
Lutropin subunit beta (Fragment)
Search

LHB

0.92	LOW QUALITY PROTEIN: lutropin subunit beta

0.76	GO:0010469	regulation of receptor activity
0.59	GO:0030728	ovulation
0.52	GO:0009755	hormone-mediated signaling pathway
0.52	GO:0007267	cell-cell signaling
0.50	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0030823	regulation of cGMP metabolic process
0.40	GO:0006701	progesterone biosynthetic process
0.39	GO:0009914	hormone transport
0.38	GO:0016486	peptide hormone processing
0.38	GO:0008584	male gonad development

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm
0.39	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P19006|HPT_CANLF
Haptoglobin
Search

0.84	Haptoglobin

0.59	GO:0006508	proteolysis
0.52	GO:0007219	Notch signaling pathway
0.49	GO:0006953	acute-phase response
0.46	GO:0042742	defense response to bacterium
0.44	GO:0002376	immune system process
0.43	GO:0098869	cellular oxidant detoxification
0.40	GO:0007596	blood coagulation
0.39	GO:2000296	negative regulation of hydrogen peroxide catabolic process
0.38	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.38	GO:0051354	negative regulation of oxidoreductase activity

0.77	GO:0030492	hemoglobin binding
0.66	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016209	antioxidant activity
0.39	GO:0004152	dihydroorotate dehydrogenase activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0005509	calcium ion binding
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0005044	scavenger receptor activity
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.60	GO:0005576	extracellular region
0.39	GO:0031838	haptoglobin-hemoglobin complex
0.36	GO:0031982	vesicle
0.35	GO:1990777	lipoprotein particle
0.34	GO:0005794	Golgi apparatus
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.66	EC:3.4.21	GO:0004252
0.39	KEGG:R01868	GO:0004152

sp|P19090|COL_CANLF
Colipase
Search

CLPS

0.97	Pancreatic colipase

0.84	GO:0007586	digestion
0.73	GO:0043085	positive regulation of catalytic activity
0.72	GO:0016042	lipid catabolic process
0.54	GO:0032094	response to food
0.37	GO:0050821	protein stabilization
0.37	GO:0001523	retinoid metabolic process
0.36	GO:0009791	post-embryonic development

0.75

GO:0008047

enzyme activator activity

0.66	GO:0005576	extracellular region
0.37	GO:0031982	vesicle

sp|P19236|TRYM_CANLF
Mastin
Search

0.74	Mast cell-restricted serine protease 7

0.61	GO:0006508	proteolysis
0.47	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.38	GO:0050878	regulation of body fluid levels
0.37	GO:0050817	coagulation
0.37	GO:0050819	negative regulation of coagulation
0.37	GO:0061045	negative regulation of wound healing
0.37	GO:0042060	wound healing
0.37	GO:0022617	extracellular matrix disassembly
0.36	GO:0048771	tissue remodeling
0.35	GO:0001835	blastocyst hatching

0.69	GO:0004252	serine-type endopeptidase activity
0.45	GO:0008201	heparin binding
0.35	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0017080	sodium channel regulator activity

0.45	GO:0005576	extracellular region
0.37	GO:0042629	mast cell granule
0.33	GO:0031225	anchored component of membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P19341|B2MG_CANLF
Beta-2-microglobulin (Fragment)
Search

0.48	Beta-2-microglobulin (Fragment)

0.81	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.74	GO:0006955	immune response
0.56	GO:1904440	positive regulation of ferrous iron import across plasma membrane
0.56	GO:1904435	regulation of transferrin receptor binding
0.56	GO:1904434	positive regulation of ferrous iron binding
0.55	GO:0071283	cellular response to iron(III) ion
0.55	GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
0.55	GO:1900122	positive regulation of receptor binding
0.54	GO:0002726	positive regulation of T cell cytokine production
0.54	GO:1900121	negative regulation of receptor binding

0.48	GO:0042802	identical protein binding
0.32	GO:0046872	metal ion binding

0.81	GO:0042612	MHC class I protein complex
0.66	GO:0005576	extracellular region
0.54	GO:1990712	HFE-transferrin receptor complex
0.50	GO:0009897	external side of plasma membrane
0.47	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.37	GO:0030670	phagocytic vesicle membrane
0.36	GO:0005925	focal adhesion
0.36	GO:0031905	early endosome lumen
0.36	GO:1904724	tertiary granule lumen

sp|P19540|FA9_CANLF
Coagulation factor IX
Search

0.85	Coagulation factor IXb

0.80	GO:0007596	blood coagulation
0.64	GO:0031638	zymogen activation
0.46	GO:0051897	positive regulation of protein kinase B signaling
0.37	GO:0017187	peptidyl-glutamic acid carboxylation
0.37	GO:0072376	protein activation cascade
0.36	GO:0006465	signal peptide processing
0.36	GO:0006888	ER to Golgi vesicle-mediated transport
0.35	GO:0030335	positive regulation of cell migration
0.33	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.33	GO:0050927	positive regulation of positive chemotaxis

0.67	GO:0004252	serine-type endopeptidase activity
0.67	GO:0005509	calcium ion binding
0.43	GO:0005543	phospholipid binding
0.34	GO:0005515	protein binding
0.34	GO:0000287	magnesium ion binding

0.63	GO:0005576	extracellular region
0.38	GO:0005796	Golgi lumen
0.37	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0031982	vesicle
0.34	GO:0031233	intrinsic component of external side of plasma membrane
0.33	GO:1905286	serine-type peptidase complex
0.30	GO:0016021	integral component of membrane

0.67

GO:0004252

sp|P19708|SAA_CANLF
Serum amyloid A protein
Search

0.94	Serum amyloid A protein (Fragment)

0.85	GO:0006953	acute-phase response
0.54	GO:0050918	positive chemotaxis
0.52	GO:0060326	cell chemotaxis
0.42	GO:0010739	positive regulation of protein kinase A signaling
0.42	GO:0050996	positive regulation of lipid catabolic process
0.42	GO:0043410	positive regulation of MAPK cascade
0.42	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.41	GO:0070372	regulation of ERK1 and ERK2 cascade
0.40	GO:0035634	response to stilbenoid
0.39	GO:0044242	cellular lipid catabolic process

0.55	GO:0042056	chemoattractant activity
0.39	GO:0035662	Toll-like receptor 4 binding
0.38	GO:0008201	heparin binding
0.36	GO:0001664	G-protein coupled receptor binding
0.34	GO:0042802	identical protein binding

0.85	GO:0034364	high-density lipoprotein particle
0.36	GO:0005881	cytoplasmic microtubule
0.36	GO:0070062	extracellular exosome
0.35	GO:0071682	endocytic vesicle lumen
0.30	GO:0016020	membrane

sp|P19863|MOTI_CANLF
Motilin
Search

0.75

Motilin

0.75

GO:0010469

regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P21262|SRP09_CANLF
Signal recognition particle 9 kDa protein
Search

SRP9

0.90	Signal recognition particle 9

0.79	GO:0045900	negative regulation of translational elongation
0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.44	GO:0065002	intracellular protein transmembrane transport

0.78	GO:0008312	7S RNA binding
0.48	GO:0005047	signal recognition particle binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.76	GO:0048500	signal recognition particle
0.48	GO:0005785	signal recognition particle receptor complex
0.37	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol

0.32

GO:0016787

sp|P21842|CMA1_CANLF
Chymase
Search

CMA1

0.95	Skeletal muscle neutral protease mekratin

0.61	GO:0006508	proteolysis
0.57	GO:0042222	interleukin-1 biosynthetic process
0.55	GO:0034769	basement membrane disassembly
0.54	GO:0032611	interleukin-1 beta production
0.44	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.41	GO:0001909	leukocyte mediated cytotoxicity
0.40	GO:0002228	natural killer cell mediated immunity
0.39	GO:0030901	midbrain development
0.39	GO:0071333	cellular response to glucose stimulus
0.39	GO:0045766	positive regulation of angiogenesis

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0042277	peptide binding
0.36	GO:0008201	heparin binding
0.33	GO:0005515	protein binding

0.54	GO:0030141	secretory granule
0.48	GO:0031012	extracellular matrix
0.37	GO:0005615	extracellular space
0.35	GO:0010494	cytoplasmic stress granule
0.35	GO:0044194	cytolytic granule
0.34	GO:0005769	early endosome
0.33	GO:0005886	plasma membrane

0.69

GO:0004252

sp|P22397|PSPC_CANLF
Pulmonary surfactant-associated protein C
Search

SP-C

0.97	Surfactant protein C (Fragment)

0.78

GO:0007585

respiratory gaseous exchange

0.51

GO:0042802

identical protein binding

0.60	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P23294|MYPR_CANLF
Myelin proteolipid protein
Search

PLP1

0.93	Myelin proteolipid protein B

0.62	GO:0022010	central nervous system myelination
0.62	GO:0014002	astrocyte development
0.61	GO:0042759	long-chain fatty acid biosynthetic process
0.58	GO:0048469	cell maturation
0.57	GO:0006954	inflammatory response
0.57	GO:0061564	axon development
0.53	GO:0010628	positive regulation of gene expression
0.41	GO:0007229	integrin-mediated signaling pathway
0.39	GO:0021762	substantia nigra development
0.35	GO:0007268	chemical synaptic transmission

0.43	GO:0019911	structural constituent of myelin sheath
0.38	GO:0042802	identical protein binding

0.60	GO:0043209	myelin sheath
0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P23438|SSRB_CANLF
Translocon-associated protein subunit beta
Search

SSR2

0.88	Translocon-associated protein subunit beta

0.44

GO:0006613

cotranslational protein targeting to membrane

0.37

GO:0051087

chaperone binding

0.65	GO:0005783	endoplasmic reticulum
0.62	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.59	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|P23685|NAC1_CANLF
Sodium/calcium exchanger 1
Search

SLC8A1

0.84	Solute carrier family 8 sodium/calcium exchanger member 1 splicing variant 1.41

0.76	GO:0035725	sodium ion transmembrane transport
0.76	GO:0006816	calcium ion transport
0.66	GO:0098735	positive regulation of the force of heart contraction
0.65	GO:0006883	cellular sodium ion homeostasis
0.65	GO:0035994	response to muscle stretch
0.63	GO:0030501	positive regulation of bone mineralization
0.60	GO:0007154	cell communication
0.43	GO:0045214	sarcomere organization
0.42	GO:0006874	cellular calcium ion homeostasis

0.85	GO:0005432	calcium:sodium antiporter activity
0.65	GO:0030506	ankyrin binding

0.53	GO:0005654	nucleoplasm
0.51	GO:0005887	integral component of plasma membrane

sp|P24406|RHOA_CANLF
Transforming protein RhoA
Search

RHOA

0.87	Transforming protein RhoA

0.78	GO:1902766	skeletal muscle satellite cell migration
0.77	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0090505	epiboly involved in wound healing
0.52	GO:0043149	stress fiber assembly
0.52	GO:1904695	positive regulation of vascular smooth muscle contraction
0.52	GO:0001998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
0.51	GO:0043366	beta selection
0.51	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.51	GO:0090324	negative regulation of oxidative phosphorylation
0.51	GO:0021861	forebrain radial glial cell differentiation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.45	GO:0017022	myosin binding
0.44	GO:0051022	Rho GDP-dissociation inhibitor binding
0.42	GO:0019003	GDP binding
0.40	GO:0004602	glutathione peroxidase activity
0.40	GO:0019904	protein domain specific binding

0.50	GO:0030027	lamellipodium
0.49	GO:0032587	ruffle membrane
0.48	GO:0097610	cell surface furrow
0.46	GO:0032155	cell division site part
0.46	GO:0043296	apical junction complex
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0030496	midbody
0.45	GO:0043197	dendritic spine
0.45	GO:0005938	cell cortex
0.44	GO:0005829	cytosol

0.40

EC:1.11.1.9

GO:0004602

sp|P24408|RAB9A_CANLF
Ras-related protein Rab-9A
Search

RAB9A

0.93	Ras-related protein Rab-9A

0.44	GO:0052405	negative regulation by host of symbiont molecular function
0.43	GO:0042147	retrograde transport, endosome to Golgi
0.42	GO:0045921	positive regulation of exocytosis
0.40	GO:0032880	regulation of protein localization
0.38	GO:0015031	protein transport
0.33	GO:0006351	transcription, DNA-templated

0.66	GO:0003924	GTPase activity
0.64	GO:0005525	GTP binding
0.46	GO:0019003	GDP binding
0.42	GO:0042802	identical protein binding

0.45	GO:0045335	phagocytic vesicle
0.43	GO:0030666	endocytic vesicle membrane
0.42	GO:0042470	melanosome
0.41	GO:0005770	late endosome
0.41	GO:0005764	lysosome
0.40	GO:0005829	cytosol
0.39	GO:0000139	Golgi membrane
0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane

sp|P24409|RAB10_CANLF
Ras-related protein Rab-10
Search

RAB10

0.83	Putative rab subfamily protein of small gtpase

0.59	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane
0.57	GO:0071786	endoplasmic reticulum tubular network organization
0.55	GO:0032869	cellular response to insulin stimulus
0.52	GO:0016197	endosomal transport
0.52	GO:0072659	protein localization to plasma membrane
0.51	GO:0098609	cell-cell adhesion
0.50	GO:0019882	antigen processing and presentation
0.49	GO:0016192	vesicle-mediated transport
0.47	GO:0017157	regulation of exocytosis
0.47	GO:0048468	cell development

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.56	GO:0098641	cadherin binding involved in cell-cell adhesion
0.56	GO:0031489	myosin V binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0051021	GDP-dissociation inhibitor binding

0.60	GO:0032593	insulin-responsive compartment
0.56	GO:0071782	endoplasmic reticulum tubular network
0.55	GO:0055037	recycling endosome
0.53	GO:0005913	cell-cell adherens junction
0.53	GO:0070382	exocytic vesicle
0.51	GO:0005929	cilium
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0005886	plasma membrane
0.42	GO:0030670	phagocytic vesicle membrane

sp|P24460|CP2BB_CANLF
Cytochrome P450 2B11
Search

CYP2B

0.97	Cytochrome P450 family 2 subfamily B member 6

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0019373	epoxygenase P450 pathway
0.48	GO:0042738	exogenous drug catabolic process
0.45	GO:0006805	xenobiotic metabolic process
0.44	GO:0008202	steroid metabolic process
0.42	GO:0042180	cellular ketone metabolic process
0.37	GO:0014070	response to organic cyclic compound
0.36	GO:0051592	response to calcium ion
0.36	GO:0010477	response to sulfur dioxide
0.35	GO:0018933	nicotine metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.52	GO:0008392	arachidonic acid epoxygenase activity
0.51	GO:0008395	steroid hydroxylase activity
0.37	GO:0019825	oxygen binding
0.34	GO:0004721	phosphoprotein phosphatase activity

0.41	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0016712

sp|P24463|CP3AC_CANLF
Cytochrome P450 3A12
Search

0.96	Cytochrome P450, subfamily IIIA (Niphedipine oxidase), polypeptide 4

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0002933	lipid hydroxylation
0.48	GO:0008202	steroid metabolic process
0.48	GO:0009822	alkaloid catabolic process
0.44	GO:0070988	demethylation
0.44	GO:0042445	hormone metabolic process
0.42	GO:0016098	monoterpenoid metabolic process
0.42	GO:1901615	organic hydroxy compound metabolic process
0.41	GO:0042738	exogenous drug catabolic process
0.41	GO:0042362	fat-soluble vitamin biosynthetic process

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.53	GO:0008395	steroid hydroxylase activity
0.42	GO:0030343	vitamin D3 25-hydroxylase activity
0.42	GO:0034875	caffeine oxidase activity
0.42	GO:0070576	vitamin D 24-hydroxylase activity
0.40	GO:0005496	steroid binding
0.38	GO:0019899	enzyme binding
0.37	GO:0019825	oxygen binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0016712

sp|P24643|CALX_CANLF
Calnexin
Search

CANX

0.86	LOW QUALITY PROTEIN: calnexin

0.69	GO:0006457	protein folding
0.56	GO:0048488	synaptic vesicle endocytosis
0.50	GO:0072583	clathrin-dependent endocytosis
0.42	GO:0048916	posterior lateral line development
0.38	GO:0007568	aging
0.36	GO:0070757	interleukin-35-mediated signaling pathway
0.36	GO:0070106	interleukin-27-mediated signaling pathway
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.34	GO:0007339	binding of sperm to zona pellucida

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.40	GO:0034185	apolipoprotein binding
0.40	GO:0035255	ionotropic glutamate receptor binding
0.38	GO:0030246	carbohydrate binding
0.34	GO:0044183	protein binding involved in protein folding
0.34	GO:0003723	RNA binding
0.33	GO:0005198	structural molecule activity

0.70	GO:0005783	endoplasmic reticulum
0.54	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.54	GO:0044233	ER-mitochondrion membrane contact site
0.53	GO:0043209	myelin sheath
0.52	GO:0031984	organelle subcompartment
0.51	GO:0045202	synapse
0.40	GO:0042470	melanosome
0.40	GO:0032839	dendrite cytoplasm
0.39	GO:0044309	neuron spine
0.39	GO:0043025	neuronal cell body

sp|P25291|GP2_CANLF
Pancreatic secretory granule membrane major glycoprotein GP2
Search

UMOD

0.94	Pancreatic zymogen granule membrane protein GP-2

0.57	GO:0072233	metanephric thick ascending limb development
0.56	GO:0072221	metanephric distal convoluted tubule development
0.56	GO:0072021	ascending thin limb development
0.55	GO:0072236	metanephric loop of Henle development
0.53	GO:0007588	excretion
0.53	GO:0007159	leukocyte cell-cell adhesion
0.53	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.53	GO:1990266	neutrophil migration
0.51	GO:2000021	regulation of ion homeostasis
0.47	GO:0048878	chemical homeostasis

0.56	GO:0005509	calcium ion binding
0.55	GO:0019864	IgG binding
0.38	GO:0003823	antigen binding
0.36	GO:0051537	2 iron, 2 sulfur cluster binding

0.64	GO:0005576	extracellular region
0.53	GO:0031225	anchored component of membrane
0.53	GO:0016324	apical plasma membrane
0.52	GO:0016323	basolateral plasma membrane
0.51	GO:0000922	spindle pole
0.50	GO:0005929	cilium
0.41	GO:0031253	cell projection membrane
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0031982	vesicle
0.35	GO:0005796	Golgi lumen

sp|P25473|CLUS_CANLF
Clusterin
Search

CLU

0.96

Clusterin

0.75	GO:0032463	negative regulation of protein homooligomerization
0.75	GO:1902847	regulation of neuronal signal transduction
0.75	GO:1905895	negative regulation of cellular response to tunicamycin
0.75	GO:1905892	negative regulation of cellular response to thapsigargin
0.75	GO:1902998	positive regulation of neurofibrillary tangle assembly
0.74	GO:0061518	microglial cell proliferation
0.73	GO:1902949	positive regulation of tau-protein kinase activity
0.73	GO:1905907	negative regulation of amyloid fibril formation
0.73	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.73	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

0.72	GO:0051787	misfolded protein binding
0.70	GO:0050750	low-density lipoprotein particle receptor binding
0.68	GO:0001540	amyloid-beta binding
0.66	GO:0031625	ubiquitin protein ligase binding
0.60	GO:0032403	protein complex binding
0.42	GO:0016887	ATPase activity
0.40	GO:0051087	chaperone binding
0.38	GO:0047485	protein N-terminus binding
0.37	GO:0097099	structural constituent of albumen

0.74	GO:0034366	spherical high-density lipoprotein particle
0.72	GO:0097418	neurofibrillary tangle
0.71	GO:0097440	apical dendrite
0.70	GO:0106003	amyloid-beta complex
0.66	GO:0048471	perinuclear region of cytoplasm
0.62	GO:0031012	extracellular matrix
0.61	GO:0009986	cell surface
0.55	GO:0042583	chromaffin granule
0.53	GO:0005739	mitochondrion
0.47	GO:0071944	cell periphery

0.42

GO:0016887

sp|P27597|CD3E_CANLF
T-cell surface glycoprotein CD3 epsilon chain
Search

CD3E

0.97	T-cell surface glycoprotein CD3 epsilon chain

0.69	GO:0007166	cell surface receptor signaling pathway
0.64	GO:0002913	positive regulation of lymphocyte anergy
0.63	GO:0002666	positive regulation of T cell tolerance induction
0.63	GO:0002667	regulation of T cell anergy
0.63	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.63	GO:0045060	negative thymic T cell selection
0.62	GO:0046641	positive regulation of alpha-beta T cell proliferation
0.62	GO:0032753	positive regulation of interleukin-4 production
0.62	GO:0031295	T cell costimulation
0.61	GO:0045879	negative regulation of smoothened signaling pathway

0.68	GO:0004888	transmembrane signaling receptor activity
0.57	GO:0017124	SH3 domain binding
0.55	GO:0042803	protein homodimerization activity
0.54	GO:0046982	protein heterodimerization activity
0.39	GO:0042608	T cell receptor binding
0.36	GO:0030159	receptor signaling complex scaffold activity
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0019901	protein kinase binding

0.64	GO:0042105	alpha-beta T cell receptor complex
0.61	GO:0001772	immunological synapse
0.60	GO:0043197	dendritic spine
0.58	GO:0009897	external side of plasma membrane
0.57	GO:0044297	cell body
0.55	GO:0005911	cell-cell junction
0.34	GO:0005887	integral component of plasma membrane

sp|P27799|S6A12_CANLF
Sodium- and chloride-dependent betaine transporter
Search

SLC6A12

0.49	Sodium- and chloride-dependent betaine transporter

0.74	GO:0015812	gamma-aminobutyric acid transport
0.54	GO:0055085	transmembrane transport
0.36	GO:0009992	cellular water homeostasis
0.35	GO:0071474	cellular hyperosmotic response
0.34	GO:0010033	response to organic substance
0.34	GO:0032259	methylation

0.78	GO:0005332	gamma-aminobutyric acid:sodium symporter activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.60	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

0.34

GO:0008168

sp|P27869|TMD11_CANLF
Transmembrane emp24 domain-containing protein 11
Search

0.91	Transmembrane emp24 protein transport domain-containing 11

0.34	GO:0009953	dorsal/ventral pattern formation
0.32	GO:0055114	oxidation-reduction process

0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0004497	monooxygenase activity
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.62	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016705

sp|P28228|CXG1_CANLF
Gap junction gamma-1 protein
Search

GJC1

0.64	Gap junction gamma-1 protein (Fragment)

0.61	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling
0.61	GO:0016264	gap junction assembly
0.57	GO:0001570	vasculogenesis
0.56	GO:0048738	cardiac muscle tissue development
0.54	GO:0007601	visual perception
0.53	GO:0007268	chemical synaptic transmission
0.52	GO:0048468	cell development
0.45	GO:0034220	ion transmembrane transport
0.37	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling
0.36	GO:0086014	atrial cardiac muscle cell action potential

0.61	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
0.49	GO:0005216	ion channel activity
0.37	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling
0.33	GO:0005515	protein binding

0.83	GO:0005922	connexin complex
0.37	GO:0043209	myelin sheath
0.35	GO:0014704	intercalated disc
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|P28490|CALR_CANLF
Calreticulin (Fragment)
Search

0.46	Calreticulin (Fragment)

0.75	GO:0002502	peptide antigen assembly with MHC class I protein complex
0.72	GO:1901164	negative regulation of trophoblast cell migration
0.71	GO:2000510	positive regulation of dendritic cell chemotaxis
0.71	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.70	GO:0090398	cellular senescence
0.69	GO:0050766	positive regulation of phagocytosis
0.69	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.69	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.69	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway
0.69	GO:0071157	negative regulation of cell cycle arrest

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.69	GO:0050681	androgen receptor binding
0.67	GO:0005178	integrin binding
0.63	GO:0031625	ubiquitin protein ligase binding
0.61	GO:0003729	mRNA binding
0.61	GO:0030246	carbohydrate binding
0.42	GO:0042562	hormone binding
0.41	GO:0042277	peptide binding
0.40	GO:0001849	complement component C1q binding

0.71	GO:0005788	endoplasmic reticulum lumen
0.70	GO:0042824	MHC class I peptide loading complex
0.65	GO:0009897	external side of plasma membrane
0.65	GO:0005844	polysome
0.64	GO:0048471	perinuclear region of cytoplasm
0.61	GO:0005635	nuclear envelope
0.60	GO:0005615	extracellular space
0.56	GO:0016529	sarcoplasmic reticulum
0.56	GO:0005829	cytosol
0.43	GO:0005790	smooth endoplasmic reticulum

sp|P29794|GLUC_CANLF
Glucagon
Search

GCG

0.97	Preproglucagon B

0.76	GO:0010469	regulation of receptor activity
0.61	GO:0010737	protein kinase A signaling
0.61	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.61	GO:1900118	negative regulation of execution phase of apoptosis
0.60	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.60	GO:0090280	positive regulation of calcium ion import
0.60	GO:0051571	positive regulation of histone H3-K4 methylation
0.60	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.60	GO:0032099	negative regulation of appetite
0.58	GO:0033138	positive regulation of peptidyl-serine phosphorylation

0.79	GO:0005179	hormone activity
0.53	GO:0042802	identical protein binding
0.50	GO:0031769	glucagon receptor binding
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.33	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.66	GO:0005576	extracellular region
0.40	GO:0005737	cytoplasm
0.38	GO:0031983	vesicle lumen
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P30552|GASR_CANLF
Gastrin/cholecystokinin type B receptor
Search

CCKBR

0.95	Cholecystokinin B receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0001696	gastric acid secretion
0.55	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0048565	digestive tract development
0.52	GO:0048732	gland development
0.38	GO:0001764	neuron migration
0.38	GO:0030900	forebrain development
0.37	GO:0007409	axonogenesis
0.37	GO:0007610	behavior

0.85	GO:0015054	gastrin receptor activity
0.60	GO:0031741	type B gastrin/cholecystokinin receptor binding
0.55	GO:0004951	cholecystokinin receptor activity
0.36	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0042277	peptide binding

0.37	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P30803|ADCY5_CANLF
Adenylate cyclase type 5
Search

ADCY5

0.92	Adenylyl cyclase type V

0.79	GO:0006171	cAMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.60	GO:1904321	response to forskolin
0.58	GO:1901655	cellular response to ketone
0.57	GO:0007212	dopamine receptor signaling pathway
0.56	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.55	GO:0035690	cellular response to drug
0.54	GO:0071396	cellular response to lipid
0.54	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.54	GO:0071407	cellular response to organic cyclic compound

0.80	GO:0004016	adenylate cyclase activity
0.55	GO:0008179	adenylate cyclase binding
0.54	GO:0097110	scaffold protein binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0008144	drug binding
0.49	GO:0043168	anion binding
0.49	GO:0004383	guanylate cyclase activity
0.48	GO:0046982	protein heterodimerization activity

0.56	GO:0005886	plasma membrane
0.51	GO:0005929	cilium
0.50	GO:0008074	guanylate cyclase complex, soluble
0.50	GO:0045111	intermediate filament cytoskeleton
0.36	GO:0098857	membrane microdomain
0.35	GO:0005768	endosome
0.34	GO:0005902	microvillus
0.34	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

0.80

EC:4.6.1.1

GO:0004016

sp|P30804|ADCY6_CANLF
Adenylate cyclase type 6
Search

ADCY6

0.79	Adenylate cyclase type 6

0.79	GO:0006171	cAMP biosynthetic process
0.66	GO:1904321	response to forskolin
0.63	GO:1901655	cellular response to ketone
0.62	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.62	GO:0007212	dopamine receptor signaling pathway
0.60	GO:0035690	cellular response to drug
0.58	GO:0071379	cellular response to prostaglandin stimulus
0.58	GO:0034695	response to prostaglandin E
0.58	GO:0071870	cellular response to catecholamine stimulus
0.56	GO:0097306	cellular response to alcohol

0.79	GO:0004016	adenylate cyclase activity
0.57	GO:0005080	protein kinase C binding
0.52	GO:0030554	adenyl nucleotide binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0097110	scaffold protein binding
0.51	GO:0008179	adenylate cyclase binding
0.50	GO:0004383	guanylate cyclase activity
0.45	GO:0046982	protein heterodimerization activity

0.55	GO:0005886	plasma membrane
0.51	GO:0008074	guanylate cyclase complex, soluble
0.48	GO:0005929	cilium
0.46	GO:0045111	intermediate filament cytoskeleton
0.36	GO:0098857	membrane microdomain
0.35	GO:0005768	endosome
0.35	GO:0005902	microvillus
0.34	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

0.79

EC:4.6.1.1

GO:0004016

sp|P30955|OLFD_CANLF
Olfactory receptor-like protein DTMT
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P30992|C5AR1_CANLF
C5a anaphylatoxin chemotactic receptor 1
Search

C5AR1

0.93	G protein-coupled receptor 77

0.85	GO:0038178	complement component C5a signaling pathway
0.67	GO:0006935	chemotaxis
0.66	GO:0050679	positive regulation of epithelial cell proliferation
0.66	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.63	GO:0090022	regulation of neutrophil chemotaxis
0.63	GO:0042789	mRNA transcription by RNA polymerase II
0.60	GO:0010759	positive regulation of macrophage chemotaxis
0.60	GO:0050900	leukocyte migration
0.60	GO:0032494	response to peptidoglycan
0.59	GO:0071624	positive regulation of granulocyte chemotaxis

0.85	GO:0004878	complement component C5a receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.40	GO:0001856	complement component C5a binding
0.34	GO:0042923	neuropeptide binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0001653	peptide receptor activity

0.62	GO:0016323	basolateral plasma membrane
0.61	GO:0045177	apical part of cell
0.46	GO:0045178	basal part of cell
0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0031410	cytoplasmic vesicle
0.37	GO:0009986	cell surface
0.35	GO:0012506	vesicle membrane
0.35	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system

sp|P31236|CASQ1_CANLF
Calsequestrin-1 (Fragment)
Search

0.58	Calsequestrin (Fragment)

0.66	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
0.65	GO:1901341	positive regulation of store-operated calcium channel activity
0.63	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.63	GO:2001256	regulation of store-operated calcium entry
0.60	GO:0045214	sarcomere organization
0.58	GO:0007029	endoplasmic reticulum organization
0.56	GO:0051258	protein polymerization
0.54	GO:0009408	response to heat
0.42	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation
0.40	GO:0007519	skeletal muscle tissue development

0.70	GO:0005509	calcium ion binding
0.55	GO:0042802	identical protein binding
0.36	GO:0005391	sodium:potassium-exchanging ATPase activity
0.36	GO:0030955	potassium ion binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0000287	magnesium ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0033018	sarcoplasmic reticulum lumen
0.56	GO:0005759	mitochondrial matrix
0.46	GO:0031674	I band
0.45	GO:0033017	sarcoplasmic reticulum membrane
0.42	GO:0014802	terminal cisterna
0.41	GO:0030315	T-tubule
0.38	GO:0005794	Golgi apparatus
0.37	GO:0005790	smooth endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0005391

sp|P31637|SC5A3_CANLF
Sodium/myo-inositol cotransporter
Search

SLC5A3

0.96	Sodium/myo-inositol cotransporter

0.57	GO:0015798	myo-inositol transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0043576	regulation of respiratory gaseous exchange
0.50	GO:0006020	inositol metabolic process
0.50	GO:0007422	peripheral nervous system development
0.38	GO:0006814	sodium ion transport
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.57	GO:0022857	transmembrane transporter activity
0.34	GO:0019843	rRNA binding
0.33	GO:0003735	structural constituent of ribosome

0.41	GO:0005887	integral component of plasma membrane
0.33	GO:0005840	ribosome

sp|P32308|OPSD_CANLF
Rhodopsin
Search

RHO

0.58

Rhodopsin

0.79	GO:0007602	phototransduction
0.75	GO:0007601	visual perception
0.72	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0016037	light absorption
0.59	GO:0071482	cellular response to light stimulus
0.56	GO:0045494	photoreceptor cell maintenance
0.55	GO:0060041	retina development in camera-type eye
0.52	GO:0009584	detection of visible light
0.47	GO:0070207	protein homotrimerization

0.76	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005502	11-cis retinal binding
0.43	GO:0042802	identical protein binding
0.41	GO:0046983	protein dimerization activity
0.39	GO:0046872	metal ion binding
0.38	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0030507	spectrin binding
0.35	GO:0002046	opsin binding
0.35	GO:1990763	arrestin family protein binding

0.66	GO:0060342	photoreceptor inner segment membrane
0.65	GO:0097381	photoreceptor disc membrane
0.64	GO:0042622	photoreceptor outer segment membrane
0.52	GO:0005911	cell-cell junction
0.50	GO:0005794	Golgi apparatus
0.36	GO:0031984	organelle subcompartment
0.35	GO:0097648	G-protein coupled receptor complex
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0030660	Golgi-associated vesicle membrane
0.34	GO:0000786	nucleosome

sp|P32750|CHLE_CANLF
Cholinesterase (Fragment)
Search

BCHE

0.76	Cholinesterase (Fragment)

0.55	GO:0051593	response to folic acid
0.54	GO:0014016	neuroblast differentiation
0.53	GO:0050805	negative regulation of synaptic transmission
0.53	GO:0043279	response to alkaloid
0.52	GO:0051384	response to glucocorticoid
0.52	GO:0007612	learning
0.50	GO:0050783	cocaine metabolic process
0.50	GO:0019695	choline metabolic process
0.50	GO:0008285	negative regulation of cell proliferation

0.85	GO:0003990	acetylcholinesterase activity
0.53	GO:0042802	identical protein binding
0.52	GO:0033265	choline binding
0.46	GO:0001540	amyloid-beta binding
0.42	GO:0019899	enzyme binding

0.64	GO:0005576	extracellular region
0.61	GO:0005641	nuclear envelope lumen
0.52	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.85

EC:3.1.1.7

GO:0003990

sp|P33685|LACB1_CANLF
Beta-lactoglobulin-1
Search

0.97	Major allergen beta-lactoglobulin

0.51	GO:1902491	negative regulation of sperm capacitation
0.50	GO:2000359	regulation of binding of sperm to zona pellucida
0.50	GO:2000667	positive regulation of interleukin-13 secretion
0.49	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production
0.48	GO:2000778	positive regulation of interleukin-6 secretion
0.45	GO:0006915	apoptotic process
0.35	GO:0007275	multicellular organism development

0.59	GO:0019841	retinol binding
0.38	GO:0042802	identical protein binding
0.38	GO:0036041	long-chain fatty acid binding

0.50

GO:0005576

extracellular region

sp|P33686|LACB2_CANLF
Beta-lactoglobulin-2
Search

0.96	Major allergen beta-lactoglobulin

0.50	GO:1902491	negative regulation of sperm capacitation
0.49	GO:2000359	regulation of binding of sperm to zona pellucida
0.49	GO:2000667	positive regulation of interleukin-13 secretion
0.48	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production
0.47	GO:2000778	positive regulation of interleukin-6 secretion
0.44	GO:0006915	apoptotic process
0.35	GO:0007275	multicellular organism development

0.59	GO:0019841	retinol binding
0.38	GO:0042802	identical protein binding
0.38	GO:0036041	long-chain fatty acid binding

0.50

GO:0005576

extracellular region

sp|P33703|APOH_CANLF
Beta-2-glycoprotein 1
Search

APOH

0.95	Apolipoprotein H

0.86	GO:0007597	blood coagulation, intrinsic pathway
0.86	GO:0034392	negative regulation of smooth muscle cell apoptotic process
0.86	GO:0051918	negative regulation of fibrinolysis
0.86	GO:0051006	positive regulation of lipoprotein lipase activity
0.86	GO:0033033	negative regulation of myeloid cell apoptotic process
0.85	GO:0031639	plasminogen activation
0.85	GO:0001937	negative regulation of endothelial cell proliferation
0.84	GO:0010596	negative regulation of endothelial cell migration
0.84	GO:0030195	negative regulation of blood coagulation
0.82	GO:0016525	negative regulation of angiogenesis

0.87	GO:0060230	lipoprotein lipase activator activity
0.73	GO:0005543	phospholipid binding
0.72	GO:0042802	identical protein binding
0.54	GO:0008201	heparin binding
0.33	GO:0030246	carbohydrate binding

0.85	GO:0042627	chylomicron
0.85	GO:0034361	very-low-density lipoprotein particle
0.84	GO:0034364	high-density lipoprotein particle
0.74	GO:0009986	cell surface
0.73	GO:0031012	extracellular matrix
0.44	GO:0070062	extracellular exosome
0.43	GO:0031089	platelet dense granule lumen
0.36	GO:0072562	blood microparticle
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P33704|ATP4B_CANLF
Potassium-transporting ATPase subunit beta
Search

ATP4B

0.81	Potassium-transporting ATPase subunit beta

0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.40	GO:0032496	response to lipopolysaccharide
0.40	GO:0007155	cell adhesion
0.40	GO:0010243	response to organonitrogen compound
0.40	GO:0048923	posterior lateral line neuromast hair cell differentiation
0.39	GO:0048840	otolith development
0.39	GO:0033577	protein glycosylation in endoplasmic reticulum
0.39	GO:0001964	startle response
0.38	GO:0010155	regulation of proton transport

0.42	GO:0008900	potassium:proton exchanging ATPase activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0051117	ATPase binding
0.33	GO:0005391	sodium:potassium-exchanging ATPase activity
0.33	GO:0001671	ATPase activator activity

0.84	GO:0005890	sodium:potassium-exchanging ATPase complex
0.36	GO:0005783	endoplasmic reticulum

0.42

EC:3.6.3.10

GO:0008900

sp|P33705|CD4_CANLF
T-cell surface glycoprotein CD4
Search

CD4

0.93	T-cell surface glycoprotein CD4 variant

0.73	GO:0006955	immune response
0.71	GO:0007155	cell adhesion
0.60	GO:0007165	signal transduction
0.58	GO:0045058	T cell selection
0.57	GO:0006948	induction by virus of host cell-cell fusion
0.56	GO:0071350	cellular response to interleukin-15
0.55	GO:0046598	positive regulation of viral entry into host cell
0.55	GO:0045657	positive regulation of monocyte differentiation
0.55	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.85	GO:0015026	coreceptor activity
0.57	GO:0042012	interleukin-16 receptor activity
0.57	GO:0042011	interleukin-16 binding
0.55	GO:0042289	MHC class II protein binding
0.53	GO:1990782	protein tyrosine kinase binding
0.48	GO:0042803	protein homodimerization activity
0.44	GO:0008270	zinc ion binding
0.37	GO:0019865	immunoglobulin binding
0.35	GO:0001618	virus receptor activity
0.35	GO:0005201	extracellular matrix structural constituent

0.51	GO:0009897	external side of plasma membrane
0.51	GO:0098857	membrane microdomain
0.47	GO:0005788	endoplasmic reticulum lumen
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0042101	T cell receptor complex
0.35	GO:0030665	clathrin-coated vesicle membrane
0.35	GO:0005769	early endosome

sp|P33706|CD8A_CANLF
T-cell surface glycoprotein CD8 alpha chain
Search

CD8A

0.82	T-cell surface glycoprotein CD8 alpha chain

0.58	GO:0045065	cytotoxic T cell differentiation
0.55	GO:0002456	T cell mediated immunity
0.47	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0050850	positive regulation of calcium-mediated signaling
0.39	GO:0051607	defense response to virus
0.36	GO:0019882	antigen processing and presentation
0.36	GO:0050776	regulation of immune response
0.36	GO:0006954	inflammatory response

0.38	GO:0019901	protein kinase binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0042288	MHC class I protein binding
0.37	GO:0015026	coreceptor activity

0.62	GO:0009897	external side of plasma membrane
0.59	GO:0044853	plasma membrane raft
0.42	GO:0044214	spanning component of plasma membrane
0.38	GO:0042101	T cell receptor complex
0.35	GO:0005576	extracellular region

sp|P33707|EPO_CANLF
Erythropoietin
Search

EPO

0.97	Erythropoietin

0.83	GO:0043249	erythrocyte maturation
0.76	GO:0010469	regulation of receptor activity
0.75	GO:0038162	erythropoietin-mediated signaling pathway
0.73	GO:1902250	regulation of erythrocyte apoptotic process
0.70	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.70	GO:0033033	negative regulation of myeloid cell apoptotic process
0.68	GO:0042541	hemoglobin biosynthetic process
0.67	GO:0010523	negative regulation of calcium ion transport into cytosol
0.67	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.67	GO:2001258	negative regulation of cation channel activity

0.87	GO:0005128	erythropoietin receptor binding
0.79	GO:0005179	hormone activity
0.63	GO:0030295	protein kinase activator activity
0.62	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.59	GO:0009986	cell surface
0.44	GO:0044297	cell body
0.30	GO:0016020	membrane

sp|P33710|GALA_CANLF
Galanin peptides (Fragment)
Search

0.74	Galanin peptides (Fragment)

0.76	GO:0010469	regulation of receptor activity
0.63	GO:1902891	negative regulation of root hair elongation
0.62	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
0.61	GO:0051795	positive regulation of timing of catagen
0.61	GO:0051464	positive regulation of cortisol secretion
0.60	GO:0010737	protein kinase A signaling
0.60	GO:0007218	neuropeptide signaling pathway
0.57	GO:0019933	cAMP-mediated signaling
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0007399	nervous system development

0.79	GO:0005179	hormone activity
0.67	GO:0031763	galanin receptor binding
0.63	GO:0004966	galanin receptor activity

0.66	GO:0005576	extracellular region
0.55	GO:0043025	neuronal cell body
0.49	GO:0030141	secretory granule
0.38	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

sp|P33711|SOMA_CANLF
Somatotropin
Search

0.76	somatotropin precursor

0.76	GO:0010469	regulation of receptor activity
0.56	GO:1903408	positive regulation of sodium:potassium-exchanging ATPase activity
0.56	GO:0030073	insulin secretion
0.55	GO:0032930	positive regulation of superoxide anion generation
0.54	GO:0032094	response to food
0.54	GO:0010960	magnesium ion homeostasis
0.53	GO:0055078	sodium ion homeostasis
0.53	GO:0042538	hyperosmotic salinity response
0.50	GO:0040018	positive regulation of multicellular organism growth
0.50	GO:0055074	calcium ion homeostasis

0.85	GO:0005131	growth hormone receptor binding
0.79	GO:0005179	hormone activity
0.40	GO:0046872	metal ion binding
0.35	GO:0005148	prolactin receptor binding
0.35	GO:0004346	glucose-6-phosphatase activity
0.34	GO:0005248	voltage-gated sodium channel activity
0.34	GO:0008083	growth factor activity
0.33	GO:0004888	transmembrane signaling receptor activity

0.73	GO:0005615	extracellular space
0.48	GO:0030141	secretory granule
0.48	GO:0005802	trans-Golgi network
0.41	GO:0005634	nucleus
0.39	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.35	GO:0070195	growth hormone receptor complex
0.35	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.34	GO:0034706	sodium channel complex

0.35	EC:3.1.3.9	GO:0004346
0.35	KEGG:R00303	GO:0004346

sp|P33712|IGF1_CANLF
Insulin-like growth factor I
Search

IGF1

0.89	IGF-I splicing variant class 1

0.76	GO:0010469	regulation of receptor activity
0.59	GO:0045725	positive regulation of glycogen biosynthetic process
0.59	GO:0048009	insulin-like growth factor receptor signaling pathway
0.58	GO:0046326	positive regulation of glucose import
0.56	GO:1904073	regulation of trophectodermal cell proliferation
0.56	GO:2001234	negative regulation of apoptotic signaling pathway
0.56	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development
0.55	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process
0.55	GO:0010560	positive regulation of glycoprotein biosynthetic process
0.55	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.59	GO:0005159	insulin-like growth factor receptor binding
0.53	GO:0005158	insulin receptor binding
0.52	GO:0005178	integrin binding
0.35	GO:0043539	protein serine/threonine kinase activator activity
0.34	GO:0005496	steroid binding

0.73	GO:0005615	extracellular space
0.60	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.55	GO:0036454	growth factor complex
0.46	GO:0070382	exocytic vesicle
0.39	GO:0005829	cytosol
0.37	GO:0031091	platelet alpha granule
0.35	GO:0005614	interstitial matrix
0.35	GO:0034774	secretory granule lumen
0.34	GO:0043025	neuronal cell body
0.30	GO:0031224	intrinsic component of membrane

sp|P33724|CAV1_CANLF
Caveolin-1
Search

CAV1

0.82

Caveolin

0.85	GO:0070836	caveola assembly
0.66	GO:0031295	T cell costimulation
0.64	GO:0031623	receptor internalization
0.63	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.62	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation
0.62	GO:1903609	negative regulation of inward rectifier potassium channel activity
0.61	GO:0033484	nitric oxide homeostasis
0.61	GO:0086098	angiotensin-activated signaling pathway involved in heart process
0.61	GO:0060355	positive regulation of cell adhesion molecule production
0.61	GO:0048550	negative regulation of pinocytosis

0.62	GO:0070320	inward rectifier potassium channel inhibitor activity
0.60	GO:0050998	nitric-oxide synthase binding
0.58	GO:0044325	ion channel binding
0.57	GO:0048365	Rac GTPase binding
0.57	GO:0051117	ATPase binding
0.56	GO:0016504	peptidase activator activity
0.56	GO:0032947	protein complex scaffold activity
0.54	GO:0030674	protein binding, bridging
0.54	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.58	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.58	GO:0002080	acrosomal membrane
0.57	GO:0005768	endosome
0.55	GO:0005925	focal adhesion
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005929	cilium
0.52	GO:0005938	cell cortex
0.48	GO:0005887	integral component of plasma membrane

sp|P33725|CXA5_CANLF
Gap junction alpha-5 protein
Search

GJA5

0.64	Gap junction alpha-5 protein (Fragment)

0.64	GO:0086044	atrial cardiac muscle cell to AV node cell communication by electrical coupling
0.63	GO:0086054	bundle of His cell to Purkinje myocyte communication by electrical coupling
0.63	GO:0098906	regulation of Purkinje myocyte action potential
0.63	GO:0098905	regulation of bundle of His cell action potential
0.63	GO:0098904	regulation of AV node cell action potential
0.63	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling
0.63	GO:0003193	pulmonary valve formation
0.62	GO:0098910	regulation of atrial cardiac muscle cell action potential
0.62	GO:0016264	gap junction assembly
0.62	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization

0.66	GO:0005243	gap junction channel activity
0.41	GO:0071253	connexin binding
0.40	GO:0097718	disordered domain specific binding
0.32	GO:0003677	DNA binding

0.83	GO:0005922	connexin complex
0.59	GO:0014704	intercalated disc
0.49	GO:0005887	integral component of plasma membrane
0.37	GO:0042995	cell projection

sp|P33726|PDE6B_CANLF
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Search

PDE6B

0.54	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

0.61	GO:0007165	signal transduction
0.58	GO:0051480	regulation of cytosolic calcium ion concentration
0.56	GO:0007601	visual perception
0.55	GO:0046037	GMP metabolic process
0.49	GO:0060041	retina development in camera-type eye
0.47	GO:0009583	detection of light stimulus
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0045494	photoreceptor cell maintenance
0.36	GO:0071482	cellular response to light stimulus
0.35	GO:0198738	cell-cell signaling by wnt

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding

0.50	GO:0001750	photoreceptor outer segment
0.39	GO:0060170	ciliary membrane

0.79

GO:0004114

sp|P33729|ICAM1_CANLF
Intercellular adhesion molecule 1 (Fragment)
Search

ICAM1

0.96	Intercellular adhesion molecule

0.76	GO:0098609	cell-cell adhesion
0.61	GO:0002457	T cell antigen processing and presentation
0.60	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.59	GO:0022614	membrane to membrane docking
0.58	GO:0002693	positive regulation of cellular extravasation
0.57	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.57	GO:0033627	cell adhesion mediated by integrin
0.57	GO:1900027	regulation of ruffle assembly
0.57	GO:0061028	establishment of endothelial barrier
0.57	GO:2000352	negative regulation of endothelial cell apoptotic process

0.64	GO:0005178	integrin binding
0.37	GO:0001618	virus receptor activity
0.35	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0003735	structural constituent of ribosome

0.57	GO:0001772	immunological synapse
0.54	GO:0070062	extracellular exosome
0.54	GO:0009897	external side of plasma membrane
0.54	GO:0098857	membrane microdomain
0.51	GO:0031012	extracellular matrix
0.47	GO:0005887	integral component of plasma membrane
0.38	GO:0005925	focal adhesion
0.34	GO:0005840	ribosome
0.33	GO:0001931	uropod
0.33	GO:0097610	cell surface furrow

sp|P33730|LYAM2_CANLF
E-selectin
Search

SELE

0.78	E-selectin

0.72	GO:0007155	cell adhesion
0.66	GO:0050900	leukocyte migration
0.50	GO:0033198	response to ATP
0.48	GO:0007202	activation of phospholipase C activity
0.47	GO:0002092	positive regulation of receptor internalization
0.46	GO:0070555	response to interleukin-1
0.43	GO:0030029	actin filament-based process
0.39	GO:0007165	signal transduction
0.37	GO:0097241	hematopoietic stem cell migration to bone marrow
0.36	GO:0070543	response to linoleic acid

0.63	GO:0030246	carbohydrate binding
0.53	GO:0005509	calcium ion binding
0.50	GO:0002020	protease binding
0.48	GO:0033691	sialic acid binding
0.48	GO:0050839	cell adhesion molecule binding
0.48	GO:0043274	phospholipase binding
0.42	GO:0004888	transmembrane signaling receptor activity
0.38	GO:0051861	glycolipid binding
0.36	GO:0046625	sphingolipid binding
0.35	GO:0008201	heparin binding

0.49	GO:0009897	external side of plasma membrane
0.49	GO:0005887	integral component of plasma membrane
0.46	GO:0005901	caveola
0.45	GO:0005905	clathrin-coated pit
0.45	GO:0030863	cortical cytoskeleton
0.44	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005615	extracellular space
0.35	GO:0030667	secretory granule membrane

sp|P33731|SRP72_CANLF
Signal recognition particle subunit SRP72
Search

SRP72

0.74	Signal recognition particle 72

0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.49	GO:0042493	response to drug
0.44	GO:0065002	intracellular protein transmembrane transport

0.74	GO:0008312	7S RNA binding
0.60	GO:0030911	TPR domain binding
0.56	GO:0005047	signal recognition particle binding
0.51	GO:0043022	ribosome binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0048500	signal recognition particle
0.49	GO:0005783	endoplasmic reticulum
0.37	GO:0005730	nucleolus
0.35	GO:0005829	cytosol

sp|P34819|BMP7_CANLF
Bone morphogenetic protein 7 (Fragment)
Search

0.65	Bone morphogenetic protein 7 (Fragment)

0.74	GO:0010469	regulation of receptor activity
0.61	GO:1905069	allantois development
0.60	GO:0072134	nephrogenic mesenchyme morphogenesis
0.60	GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development
0.60	GO:0072125	negative regulation of glomerular mesangial cell proliferation
0.60	GO:0072040	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
0.60	GO:0021502	neural fold elevation formation
0.60	GO:0072133	metanephric mesenchyme morphogenesis
0.60	GO:1905294	positive regulation of neural crest cell differentiation
0.60	GO:1905310	regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

0.77	GO:0008083	growth factor activity
0.50	GO:0070700	BMP receptor binding
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.40	GO:0008201	heparin binding

0.65	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P34962|NMU_CANLF
Neuromedin-U-25
Search

NMU

0.90	Neuromedin-U-25

0.85	GO:0006940	regulation of smooth muscle contraction
0.51	GO:0007218	neuropeptide signaling pathway
0.49	GO:2000821	regulation of grooming behavior
0.49	GO:0010469	regulation of receptor activity
0.48	GO:0097009	energy homeostasis
0.47	GO:0060259	regulation of feeding behavior
0.47	GO:0001659	temperature homeostasis

0.59	GO:0031839	type 1 neuromedin U receptor binding
0.59	GO:0031840	type 2 neuromedin U receptor binding
0.50	GO:0005179	hormone activity

0.45

GO:0005576

extracellular region

sp|P35521|ICLN_CANLF
Methylosome subunit pICln
Search

CLNS1A

0.93	Methylosome subunit pICln

0.84	GO:0006884	cell volume homeostasis
0.80	GO:0000387	spliceosomal snRNP assembly
0.76	GO:0006821	chloride transport
0.44	GO:0048675	axon extension
0.34	GO:0071805	potassium ion transmembrane transport
0.34	GO:0098661	inorganic anion transmembrane transport
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.50	GO:0046982	protein heterodimerization activity
0.37	GO:1990935	splicing factor binding
0.36	GO:0061778	intracellular chloride channel activity
0.34	GO:0005267	potassium channel activity
0.34	GO:0022839	ion gated channel activity
0.34	GO:0008381	mechanosensitive ion channel activity
0.34	GO:0003723	RNA binding

0.85	GO:0034709	methylosome
0.85	GO:0034715	pICln-Sm protein complex
0.68	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.48	GO:0005654	nucleoplasm
0.39	GO:0005856	cytoskeleton
0.34	GO:0031213	RSF complex
0.30	GO:0016021	integral component of membrane

sp|P35834|CSF3_CANLF
Granulocyte colony-stimulating factor
Search

CSF3

0.96	Colony stimulating factor

0.80	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.79	GO:0042993	positive regulation of transcription factor import into nucleus
0.78	GO:0045639	positive regulation of myeloid cell differentiation
0.78	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.77	GO:0051897	positive regulation of protein kinase B signaling
0.77	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.77	GO:0032092	positive regulation of protein binding
0.76	GO:0010469	regulation of receptor activity
0.75	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.74	GO:0006955	immune response

0.85	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.81	GO:0005125	cytokine activity
0.65	GO:0019899	enzyme binding
0.48	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P38377|S61A1_CANLF
Protein transport protein Sec61 subunit alpha isoform 1
Search

SEC61A1

0.89	Transport protein Sec61 subunit alpha 1

0.64	GO:0015031	protein transport
0.58	GO:0039019	pronephric nephron development
0.52	GO:0007029	endoplasmic reticulum organization
0.51	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.51	GO:0016049	cell growth
0.48	GO:0046907	intracellular transport
0.48	GO:0090150	establishment of protein localization to membrane
0.39	GO:0034341	response to interferon-gamma
0.37	GO:0021986	habenula development
0.35	GO:0036498	IRE1-mediated unfolded protein response

0.48	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding
0.33	GO:0022857	transmembrane transporter activity

0.50	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005791	rough endoplasmic reticulum
0.35	GO:0030670	phagocytic vesicle membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P38400|GNAI2_CANLF
Guanine nucleotide-binding protein G(i) subunit alpha-2
Search

GNAI2

0.93	Guanine nucleotide binding protein alpha inhibiting 2

0.81	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.51	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.49	GO:0008283	cell proliferation
0.48	GO:0001973	adenosine receptor signaling pathway
0.47	GO:0007214	gamma-aminobutyric acid signaling pathway
0.46	GO:0051301	cell division
0.38	GO:0050805	negative regulation of synaptic transmission
0.38	GO:0007049	cell cycle
0.37	GO:0000186	activation of MAPKK activity
0.37	GO:0051924	regulation of calcium ion transport

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0001664	G-protein coupled receptor binding
0.35	GO:0046872	metal ion binding

0.54	GO:0030496	midbody
0.51	GO:0005813	centrosome
0.50	GO:0030425	dendrite
0.50	GO:0044297	cell body
0.47	GO:1905360	GTPase complex
0.47	GO:0005654	nucleoplasm
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0005829	cytosol
0.42	GO:0098797	plasma membrane protein complex
0.37	GO:0045121	membrane raft

sp|P38486|LEG3_CANLF
Galectin-3
Search

LGALS3

0.61

Galectin

0.59	GO:0048246	macrophage chemotaxis
0.59	GO:0048245	eosinophil chemotaxis
0.58	GO:0090280	positive regulation of calcium ion import
0.58	GO:0002548	monocyte chemotaxis
0.58	GO:0071677	positive regulation of mononuclear cell migration
0.58	GO:0070232	regulation of T cell apoptotic process
0.57	GO:0045806	negative regulation of endocytosis
0.57	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.57	GO:0030593	neutrophil chemotaxis
0.57	GO:0050918	positive chemotaxis

0.66	GO:0030246	carbohydrate binding
0.61	GO:0019863	IgE binding
0.58	GO:0042056	chemoattractant activity
0.57	GO:0043236	laminin binding
0.37	GO:0050785	advanced glycation end-product receptor activity
0.36	GO:0034988	Fc-gamma receptor I complex binding
0.36	GO:0005544	calcium-dependent phospholipid binding
0.36	GO:0005509	calcium ion binding
0.34	GO:0003676	nucleic acid binding
0.33	GO:0045296	cadherin binding

0.57	GO:0001772	immunological synapse
0.51	GO:0031012	extracellular matrix
0.46	GO:0005634	nucleus
0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.38	GO:0097386	glial cell projection
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005615	extracellular space
0.37	GO:0009897	external side of plasma membrane
0.37	GO:1903561	extracellular vesicle

0.32

EC:2.7.1

GO:0016773

sp|P39881|CUX1_CANLF
Homeobox protein cut-like 1 (Fragment)
Search

0.51	Homeobox protein cut-like

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.44	GO:0048193	Golgi vesicle transport
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.42	GO:0007275	multicellular organism development
0.40	GO:1900006	positive regulation of dendrite development
0.40	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.39	GO:0031346	positive regulation of cell projection organization

0.62	GO:0043565	sequence-specific DNA binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.39	GO:0030674	protein binding, bridging
0.38	GO:0004713	protein tyrosine kinase activity

0.61	GO:0005634	nucleus
0.52	GO:0005794	Golgi apparatus
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.42	GO:0098588	bounding membrane of organelle
0.37	GO:0005829	cytosol

0.38

EC:2.7.10

GO:0004713

sp|P40321|IL2RG_CANLF
Cytokine receptor common subunit gamma
Search

IL2RG

0.93	Cytokine receptor common subunit gamma

0.79	GO:0019221	cytokine-mediated signaling pathway
0.48	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.47	GO:0033089	positive regulation of T cell differentiation in thymus
0.47	GO:0045579	positive regulation of B cell differentiation
0.42	GO:0010628	positive regulation of gene expression
0.39	GO:0098756	response to interleukin-21
0.39	GO:0071355	cellular response to interleukin-9
0.39	GO:0098761	cellular response to interleukin-7
0.39	GO:0071350	cellular response to interleukin-15
0.38	GO:0071352	cellular response to interleukin-2

0.81	GO:0004896	cytokine receptor activity
0.49	GO:0019976	interleukin-2 binding
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.46	GO:0009897	external side of plasma membrane
0.36	GO:0005768	endosome
0.35	GO:0005829	cytosol
0.35	GO:0005887	integral component of plasma membrane

sp|P40765|COPA_CANLF
Coatomer subunit alpha (Fragment)
Search

0.61	Coatomer subunit alpha (Fragment)

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.53	GO:0030157	pancreatic juice secretion
0.46	GO:0030903	notochord development
0.45	GO:0061053	somite development
0.41	GO:1905345	protein localization to cleavage furrow
0.40	GO:0007112	male meiosis cytokinesis
0.39	GO:0010883	regulation of lipid storage
0.38	GO:0000902	cell morphogenesis
0.37	GO:0010469	regulation of receptor activity

0.61	GO:0005198	structural molecule activity
0.37	GO:0005179	hormone activity
0.32	GO:0005215	transporter activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0016740	transferase activity

0.79	GO:0030126	COPI vesicle coat
0.70	GO:0000139	Golgi membrane
0.46	GO:0005615	extracellular space
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:1903561	extracellular vesicle
0.34	GO:0030133	transport vesicle
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

sp|P41148|ENPL_CANLF
Endoplasmin
Search

HSP90B1

0.84	Heat shock protein HSP 90-alpha

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.58	GO:0031247	actin rod assembly
0.57	GO:0071318	cellular response to ATP
0.55	GO:1903513	endoplasmic reticulum to cytosol transport
0.55	GO:0032527	protein exit from endoplasmic reticulum
0.53	GO:0036293	response to decreased oxygen levels
0.52	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.51	GO:0043666	regulation of phosphoprotein phosphatase activity
0.51	GO:0043066	negative regulation of apoptotic process

0.71	GO:0051082	unfolded protein binding
0.55	GO:0050750	low-density lipoprotein particle receptor binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0019903	protein phosphatase binding
0.43	GO:0003723	RNA binding
0.34	GO:0019104	DNA N-glycosylase activity
0.34	GO:0005509	calcium ion binding

0.55	GO:0005788	endoplasmic reticulum lumen
0.53	GO:0030496	midbody
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0034663	endoplasmic reticulum chaperone complex
0.48	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005829	cytosol
0.43	GO:0042470	melanosome
0.39	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.34

EC:3.2.2

GO:0019104

sp|P41323|IL6_CANLF
Interleukin-6
Search

IL6

0.95	Interleukin 6 (Interferon, beta 2)

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.60	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment
0.60	GO:0006954	inflammatory response
0.58	GO:0002252	immune effector process
0.56	GO:0001781	neutrophil apoptotic process
0.55	GO:0032966	negative regulation of collagen biosynthetic process
0.54	GO:0071354	cellular response to interleukin-6
0.54	GO:0051024	positive regulation of immunoglobulin secretion
0.53	GO:0002675	positive regulation of acute inflammatory response

0.86	GO:0005138	interleukin-6 receptor binding
0.80	GO:0005125	cytokine activity
0.59	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.55	GO:0005896	interleukin-6 receptor complex
0.35	GO:0005788	endoplasmic reticulum lumen

sp|P41324|IL8_CANLF
Interleukin-8
Search

CXCL8

0.45	Multifunctional fusion protein (Fragment)

0.85	GO:0030593	neutrophil chemotaxis
0.85	GO:0042119	neutrophil activation
0.79	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.60	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.59	GO:0050930	induction of positive chemotaxis
0.58	GO:2000535	regulation of entry of bacterium into host cell
0.56	GO:0048566	embryonic digestive tract development
0.56	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway

0.86	GO:0005153	interleukin-8 receptor binding
0.84	GO:0008009	chemokine activity
0.36	GO:0048020	CCR chemokine receptor binding
0.34	GO:0008083	growth factor activity
0.32	GO:0046983	protein dimerization activity

0.73	GO:0005615	extracellular space
0.37	GO:0005622	intracellular

sp|P41547|CALC_CANLF
Calcitonin
Search

CALCA

0.94	Salmon calcitonin-IV

0.76	GO:0010469	regulation of receptor activity
0.49	GO:0001984	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
0.48	GO:0045779	negative regulation of bone resorption
0.48	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.48	GO:0007190	activation of adenylate cyclase activity
0.47	GO:0002548	monocyte chemotaxis
0.47	GO:0031645	negative regulation of neurological system process
0.47	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.47	GO:0045986	negative regulation of smooth muscle contraction
0.47	GO:1990090	cellular response to nerve growth factor stimulus

0.79	GO:0005179	hormone activity
0.51	GO:0031716	calcitonin receptor binding
0.43	GO:0042802	identical protein binding
0.34	GO:0032403	protein complex binding

0.66	GO:0005576	extracellular region
0.46	GO:0043195	terminal bouton
0.44	GO:0043025	neuronal cell body
0.36	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P42161|IFNG_CANLF
Interferon gamma
Search

IFNG

0.94	Interferon gamma

0.74	GO:0006955	immune response
0.72	GO:0040008	regulation of growth
0.71	GO:0051607	defense response to virus
0.69	GO:0010469	regulation of receptor activity
0.62	GO:0060552	positive regulation of fructose 1,6-bisphosphate metabolic process
0.62	GO:0060549	regulation of fructose 1,6-bisphosphate 1-phosphatase activity
0.62	GO:0032834	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
0.62	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.61	GO:0060557	positive regulation of vitamin D biosynthetic process
0.61	GO:0032747	positive regulation of interleukin-23 production

0.86	GO:0005133	interferon-gamma receptor binding
0.74	GO:0005125	cytokine activity

0.68	GO:0005615	extracellular space
0.38	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P42705|TPO_CANLF
Thrombopoietin
Search

THPO

0.97	Thrombopoietin

0.80	GO:0008283	cell proliferation
0.77	GO:0038163	thrombopoietin-mediated signaling pathway
0.76	GO:0045654	positive regulation of megakaryocyte differentiation
0.76	GO:0010469	regulation of receptor activity
0.75	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.71	GO:0051897	positive regulation of protein kinase B signaling
0.70	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.67	GO:0030099	myeloid cell differentiation
0.38	GO:0071222	cellular response to lipopolysaccharide

0.81	GO:0005125	cytokine activity
0.79	GO:0005179	hormone activity
0.38	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

sp|P42929|HSPB1_CANLF
Heat shock protein beta-1
Search

HSPB1

0.90	LOW QUALITY PROTEIN: heat shock protein beta-1

0.85	GO:0099641	anterograde axonal protein transport
0.80	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
0.79	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.78	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.77	GO:0032731	positive regulation of interleukin-1 beta production
0.75	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.72	GO:0045766	positive regulation of angiogenesis
0.72	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.71	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.71	GO:0061077	chaperone-mediated protein folding

0.82	GO:0008426	protein kinase C inhibitor activity
0.78	GO:0044183	protein binding involved in protein folding
0.76	GO:0005080	protein kinase C binding
0.69	GO:0042803	protein homodimerization activity
0.44	GO:0043130	ubiquitin binding
0.40	GO:0005212	structural constituent of eye lens
0.37	GO:0003723	RNA binding
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0046872	metal ion binding

0.77	GO:1904115	axon cytoplasm
0.73	GO:0030018	Z disc
0.61	GO:0005634	nucleus
0.51	GO:0005819	spindle
0.50	GO:0005886	plasma membrane
0.42	GO:0031012	extracellular matrix
0.42	GO:1905369	endopeptidase complex
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome
0.40	GO:0070013	intracellular organelle lumen

0.34

GO:0004114

sp|P43240|AGTR1_CANLF
Type-1 angiotensin II receptor
Search

AGTR1

0.97	Type-1 angiotensin II receptor

0.82	GO:0038166	angiotensin-activated signaling pathway
0.79	GO:0019229	regulation of vasoconstriction
0.41	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.41	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.40	GO:0042756	drinking behavior
0.40	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure
0.40	GO:0071549	cellular response to dexamethasone stimulus
0.40	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.40	GO:0045777	positive regulation of blood pressure

0.84	GO:0004945	angiotensin type II receptor activity
0.43	GO:0001596	angiotensin type I receptor activity
0.40	GO:0031711	bradykinin receptor binding
0.40	GO:0017046	peptide hormone binding
0.39	GO:0043621	protein self-association
0.38	GO:0031748	D1 dopamine receptor binding
0.37	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0019901	protein kinase binding

0.40	GO:0031983	vesicle lumen
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0012506	vesicle membrane
0.36	GO:0055037	recycling endosome
0.36	GO:0030425	dendrite
0.36	GO:0031968	organelle outer membrane
0.35	GO:0005794	Golgi apparatus
0.33	GO:0005887	integral component of plasma membrane

sp|P43698|TITF1_CANLF
Thyroid transcription factor 1
Search

NKX2-1

0.90	Thyroid transcription factor 1

0.62	GO:0021536	diencephalon development
0.62	GO:0021761	limbic system development
0.59	GO:0060486	Clara cell differentiation
0.58	GO:0030878	thyroid gland development
0.58	GO:0060510	Type II pneumocyte differentiation
0.58	GO:0021798	forebrain dorsal/ventral pattern formation
0.58	GO:0060430	lung saccule development
0.58	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.58	GO:0021892	cerebral cortex GABAergic interneuron differentiation
0.58	GO:0060441	epithelial tube branching involved in lung morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0044213	intronic transcription regulatory region DNA binding
0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0001047	core promoter binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.50	GO:0019899	enzyme binding
0.37	GO:0008134	transcription factor binding
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part

sp|P47240|PAX8_CANLF
Paired box protein Pax-8
Search

PAX8

0.83	Paired box protein Pax-8

0.69	GO:0007275	multicellular organism development
0.61	GO:2000611	positive regulation of thyroid hormone generation
0.60	GO:2000612	regulation of thyroid-stimulating hormone secretion
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1900217	regulation of apoptotic process involved in metanephric nephron tubule development
0.57	GO:0071371	cellular response to gonadotropin stimulus
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0060231	mesenchymal to epithelial transition
0.56	GO:1900211	regulation of mesenchymal cell apoptotic process involved in metanephros development

0.56	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.40	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0004996	thyroid-stimulating hormone receptor activity
0.36	GO:0035326	enhancer binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex

sp|P47842|GTR3_CANLF
Solute carrier family 2, facilitated glucose transporter member 3
Search

SLC2A3

0.75	Glucose transporter

0.69	GO:1904659	glucose transmembrane transport
0.53	GO:0070837	dehydroascorbic acid transport
0.36	GO:0046323	glucose import
0.36	GO:0007275	multicellular organism development
0.35	GO:1904016	response to Thyroglobulin triiodothyronine
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019852	L-ascorbic acid metabolic process
0.35	GO:0030154	cell differentiation
0.35	GO:0009749	response to glucose

0.70	GO:0005355	glucose transmembrane transporter activity
0.53	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.44	GO:0005536	glucose binding
0.36	GO:0033222	xylose binding
0.35	GO:0016936	galactoside binding
0.34	GO:0019900	kinase binding

0.51	GO:0002080	acrosomal membrane
0.41	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0030672	synaptic vesicle membrane
0.34	GO:0045121	membrane raft
0.33	GO:0005634	nucleus

sp|P47983|ZP2_CANLF
Zona pellucida sperm-binding protein 2
Search

ZP2

0.97	Zona pellucida protein subunit A

0.70	GO:0060468	prevention of polyspermy
0.66	GO:0007339	binding of sperm to zona pellucida
0.39	GO:0060046	regulation of acrosome reaction
0.38	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.34	GO:0007165	signal transduction

0.67	GO:0032190	acrosin binding
0.56	GO:0042802	identical protein binding
0.37	GO:0015026	coreceptor activity

0.65	GO:0005771	multivesicular body
0.59	GO:0005576	extracellular region
0.55	GO:0005783	endoplasmic reticulum
0.46	GO:0005886	plasma membrane
0.38	GO:0016234	inclusion body
0.35	GO:0042597	periplasmic space
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P48300|FUCO_CANLF
Tissue alpha-L-fucosidase
Search

FUCA1

0.91	Tissue alpha-L-fucosidase

0.79	GO:0006004	fucose metabolic process
0.57	GO:0016139	glycoside catabolic process
0.37	GO:0019377	glycolipid catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006027	glycosaminoglycan catabolic process
0.32	GO:0038171	cannabinoid signaling pathway

0.80	GO:0004560	alpha-L-fucosidase activity
0.35	GO:0004419	hydroxymethylglutaryl-CoA lyase activity
0.34	GO:0030246	carbohydrate binding
0.32	GO:0004949	cannabinoid receptor activity
0.32	GO:0003676	nucleic acid binding

0.40	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:3.2.1.51	GO:0004560
0.35	KEGG:R01360	GO:0004419

sp|P48411|IL10_CANLF
Interleukin-10
Search

IL10

0.92	Viral interleukin-10 homolog

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.64	GO:0002904	positive regulation of B cell apoptotic process
0.63	GO:0032800	receptor biosynthetic process
0.63	GO:0002740	negative regulation of cytokine secretion involved in immune response
0.63	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.62	GO:0030889	negative regulation of B cell proliferation
0.62	GO:0032715	negative regulation of interleukin-6 production
0.60	GO:0051384	response to glucocorticoid
0.59	GO:0050715	positive regulation of cytokine secretion

0.80	GO:0005125	cytokine activity
0.44	GO:0005141	interleukin-10 receptor binding
0.34	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

sp|P48749|CSF2_CANLF
Granulocyte-macrophage colony-stimulating factor
Search

CSF2

0.97	Granulocyte-macrophage colony-stimulating factor

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.69	GO:0045918	negative regulation of cytolysis
0.68	GO:0032747	positive regulation of interleukin-23 production
0.68	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.68	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.67	GO:0071803	positive regulation of podosome assembly
0.67	GO:0043011	myeloid dendritic cell differentiation
0.66	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.65	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein

0.87	GO:0005129	granulocyte macrophage colony-stimulating factor receptor binding
0.78	GO:0008083	growth factor activity
0.65	GO:0005125	cytokine activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.46	GO:0043227	membrane-bounded organelle
0.44	GO:0043229	intracellular organelle

0.36

EC:2.7.10

GO:0004713

sp|P48831|ZP3_CANLF
Zona pellucida sperm-binding protein 3
Search

ZP3

0.92	Zona pellucida protein subunit C

0.63	GO:0001809	positive regulation of type IV hypersensitivity
0.63	GO:2000387	regulation of antral ovarian follicle growth
0.63	GO:2000386	positive regulation of ovarian follicle development
0.62	GO:0035803	egg coat formation
0.61	GO:2000344	positive regulation of acrosome reaction
0.61	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.59	GO:0007339	binding of sperm to zona pellucida
0.59	GO:0032753	positive regulation of interleukin-4 production
0.59	GO:0001825	blastocyst formation
0.59	GO:0090280	positive regulation of calcium ion import

0.55	GO:0035804	structural constituent of egg coat
0.53	GO:0048018	receptor ligand activity
0.52	GO:0032190	acrosin binding
0.45	GO:0030246	carbohydrate binding
0.40	GO:0042802	identical protein binding

0.63	GO:0005576	extracellular region
0.45	GO:0045177	apical part of cell
0.43	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.34	GO:0043234	protein complex
0.33	GO:0035805	egg coat
0.30	GO:0016021	integral component of membrane

sp|P49256|LMAN2_CANLF
Vesicular integral-membrane protein VIP36
Search

LMAN2

0.94	Vesicular integral-membrane protein VIP36

0.58	GO:0050766	positive regulation of phagocytosis
0.55	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.37	GO:0015031	protein transport
0.34	GO:0005975	carbohydrate metabolic process

0.58	GO:0005537	mannose binding
0.53	GO:0031072	heat shock protein binding
0.34	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0046872	metal ion binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0009986	cell surface
0.51	GO:0005794	Golgi apparatus
0.51	GO:0005615	extracellular space
0.48	GO:0005887	integral component of plasma membrane
0.38	GO:0031984	organelle subcompartment
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0044432	endoplasmic reticulum part
0.37	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle

0.34

GO:0016757

sp|P49670|SMS_CANLF
Somatostatin
Search

SST

0.97	Preprosomatostatin I

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0030334	regulation of cell migration
0.45	GO:0007267	cell-cell signaling
0.44	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0010447	response to acidic pH
0.40	GO:0006972	hyperosmotic response
0.40	GO:0043200	response to amino acid
0.39	GO:0048545	response to steroid hormone
0.38	GO:0009408	response to heat
0.37	GO:0042493	response to drug

0.79	GO:0005179	hormone activity
0.34	GO:0031878	type 1 somatostatin receptor binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.39	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|P49818|CH60_CANLF
60 kDa heat shock protein, mitochondrial (Fragment)
Search

0.10	60 kDa heat shock protein, mitochondrial (Fragment)

0.30	GO:0030554	adenyl nucleotide binding
0.30	GO:0043167	ion binding
0.30	GO:0097367	carbohydrate derivative binding
0.30	GO:0008144	drug binding
0.30	GO:0016787	hydrolase activity

0.30	GO:0070013	intracellular organelle lumen
0.30	GO:0005739	mitochondrion
0.30	GO:0043234	protein complex
0.30	GO:0044446	intracellular organelle part

0.30

GO:0016787

sp|P49819|DLDH_CANLF
Dihydrolipoyl dehydrogenase, mitochondrial
Search

DLD

0.46	Dihydrolipoyl dehydrogenase

0.68	GO:0045454	cell redox homeostasis
0.59	GO:0022900	electron transport chain
0.59	GO:0018335	protein succinylation
0.55	GO:0048240	sperm capacitation
0.52	GO:0007369	gastrulation
0.52	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.50	GO:0042391	regulation of membrane potential
0.44	GO:0006119	oxidative phosphorylation
0.43	GO:0045333	cellular respiration
0.43	GO:0060047	heart contraction

0.77	GO:0004148	dihydrolipoyl dehydrogenase activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.61	GO:0009055	electron transfer activity
0.56	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.41	GO:0043544	lipoamide binding
0.36	GO:0051287	NAD binding
0.33	GO:0005515	protein binding

0.56	GO:0043159	acrosomal matrix
0.53	GO:0045252	oxoglutarate dehydrogenase complex
0.52	GO:0043209	myelin sheath
0.52	GO:0045254	pyruvate dehydrogenase complex
0.51	GO:0005929	cilium
0.48	GO:0031974	membrane-enclosed lumen
0.46	GO:0044428	nuclear part
0.45	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:1.8.1.4	GO:0004148
0.56	KEGG:R00209	GO:0034604

sp|P49820|NDUV2_CANLF
NADH dehydrogenase [ubiquinone] flavoprotein 2 (Fragment)
Search

0.10	NADH dehydrogenase [ubiquinone] flavoprotein 2 (Fragment)

0.30

GO:0055114

oxidation-reduction process

0.30	GO:0050136	NADH dehydrogenase (quinone) activity
0.30	GO:0051540	metal cluster binding
0.30	GO:0043167	ion binding
0.30	GO:0048037	cofactor binding

0.30	GO:0031975	envelope
0.30	GO:0070469	respiratory chain
0.30	GO:0005737	cytoplasm
0.30	GO:0031090	organelle membrane
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044446	intracellular organelle part

0.30

EC:1.6.99.5

GO:0050136

sp|P49822|ALBU_CANLF
Serum albumin
Search

ALB

0.95	Serum albumin

0.60	GO:0051659	maintenance of mitochondrion location
0.57	GO:0019836	hemolysis by symbiont of host erythrocytes
0.53	GO:0009267	cellular response to starvation
0.53	GO:0043066	negative regulation of apoptotic process
0.49	GO:0001542	ovulation from ovarian follicle
0.49	GO:0042448	progesterone metabolic process
0.48	GO:0060395	SMAD protein signal transduction
0.37	GO:0070541	response to platinum ion
0.37	GO:0007584	response to nutrient
0.37	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep

0.57	GO:0005504	fatty acid binding
0.55	GO:0015643	toxic substance binding
0.53	GO:0019825	oxygen binding
0.49	GO:0051087	chaperone binding
0.47	GO:0042802	identical protein binding
0.47	GO:0030170	pyridoxal phosphate binding
0.42	GO:0003677	DNA binding
0.39	GO:0046872	metal ion binding
0.35	GO:0019899	enzyme binding

0.73	GO:0005615	extracellular space
0.51	GO:0043209	myelin sheath
0.50	GO:1903561	extracellular vesicle
0.46	GO:0005794	Golgi apparatus
0.46	GO:0005783	endoplasmic reticulum
0.44	GO:0043234	protein complex
0.36	GO:0060417	yolk
0.36	GO:0005604	basement membrane
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen

sp|P49823|ODPA_CANLF
Pyruvate dehydrogenase E1 component subunit alpha, somatic form (Fragment)
Search

0.10	Pyruvate dehydrogenase E1 component subunit alpha, somatic form (Fragment)

0.30	GO:0051188	cofactor biosynthetic process
0.30	GO:0072350	tricarboxylic acid metabolic process
0.30	GO:0009060	aerobic respiration
0.30	GO:0044272	sulfur compound biosynthetic process
0.30	GO:1901576	organic substance biosynthetic process
0.30	GO:0032787	monocarboxylic acid metabolic process
0.30	GO:0005996	monosaccharide metabolic process
0.30	GO:0006637	acyl-CoA metabolic process

0.30

GO:0016491

oxidoreductase activity

0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:1902494	catalytic complex
0.30	GO:0005737	cytoplasm
0.30	GO:0043229	intracellular organelle
0.30	GO:0044422	organelle part

0.30

GO:0016491

sp|P49824|MYH7_CANLF
Myosin-7
Search

MYH7

0.90	Cardiac myosin heavy chain-alpha

0.74	GO:0007018	microtubule-based movement
0.56	GO:0030049	muscle filament sliding
0.55	GO:0007512	adult heart development
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0014887	cardiac muscle adaptation
0.54	GO:0003300	cardiac muscle hypertrophy
0.54	GO:0002026	regulation of the force of heart contraction
0.54	GO:0006941	striated muscle contraction
0.53	GO:0055008	cardiac muscle tissue morphogenesis
0.53	GO:0003229	ventricular cardiac muscle tissue development

0.76	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030898	actin-dependent ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.44	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.53	GO:0030016	myofibril
0.53	GO:0044449	contractile fiber part
0.53	GO:0097517	contractile actin filament bundle
0.53	GO:0042641	actomyosin
0.33	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.33

EC:3.4.23

GO:0004190

sp|P49894|IOD1_CANLF
Type I iodothyronine deiodinase
Search

DIO1

0.75	Type I iodothyronine deiodinase

0.78	GO:0042446	hormone biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.37	GO:0061074	regulation of neural retina development
0.37	GO:0006590	thyroid hormone generation
0.35	GO:0045454	cell redox homeostasis
0.34	GO:0006091	generation of precursor metabolites and energy

0.85	GO:0004800	thyroxine 5'-deiodinase activity
0.41	GO:0008430	selenium binding

0.45	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:1.97.1.10

GO:0004800

sp|P49926|CRF_CANLF
Corticoliberin
Search

CRH

0.97	Corticotoropin releasing hormone

0.75	GO:0010469	regulation of receptor activity
0.66	GO:2000851	positive regulation of glucocorticoid secretion
0.65	GO:0051461	positive regulation of corticotropin secretion
0.65	GO:0051462	regulation of cortisol secretion
0.64	GO:0001963	synaptic transmission, dopaminergic
0.62	GO:1900449	regulation of glutamate receptor signaling pathway
0.62	GO:2001025	positive regulation of response to drug
0.61	GO:0006704	glucocorticoid biosynthetic process
0.60	GO:2001257	regulation of cation channel activity
0.59	GO:0035641	locomotory exploration behavior

0.79	GO:0005179	hormone activity
0.43	GO:0051430	corticotropin-releasing hormone receptor 1 binding
0.43	GO:0051431	corticotropin-releasing hormone receptor 2 binding
0.33	GO:0004601	peroxidase activity
0.33	GO:0004849	uridine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding

0.66	GO:0005576	extracellular region
0.43	GO:0043196	varicosity
0.42	GO:0043204	perikaryon
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33	EC:1.11.1.7	GO:0004601
0.33	KEGG:R03532	GO:0004601

sp|P50551|VASP_CANLF
Vasodilator-stimulated phosphoprotein
Search

VASP

0.95	Vasodilator-stimulated phosphoprotein b

0.81	GO:0008154	actin polymerization or depolymerization
0.74	GO:0051289	protein homotetramerization
0.63	GO:0030838	positive regulation of actin filament polymerization
0.51	GO:0001843	neural tube closure
0.50	GO:0007411	axon guidance
0.46	GO:1900028	negative regulation of ruffle assembly
0.45	GO:0051496	positive regulation of stress fiber assembly
0.44	GO:0010633	negative regulation of epithelial cell migration
0.44	GO:0071346	cellular response to interferon-gamma
0.36	GO:0034329	cell junction assembly

0.70	GO:0017124	SH3 domain binding
0.65	GO:0003779	actin binding
0.57	GO:0005522	profilin binding
0.49	GO:0045296	cadherin binding

0.61	GO:0005856	cytoskeleton
0.56	GO:0042995	cell projection
0.54	GO:0005925	focal adhesion
0.53	GO:0031252	cell leading edge
0.45	GO:0005829	cytosol
0.43	GO:0045335	phagocytic vesicle
0.40	GO:0005886	plasma membrane
0.39	GO:0005923	bicellular tight junction
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P50994|ANXA4_CANLF
Annexin A4
Search

ANXA4

0.60

Annexin

0.57	GO:2000483	negative regulation of interleukin-8 secretion
0.54	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.54	GO:0007219	Notch signaling pathway
0.52	GO:0030855	epithelial cell differentiation
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0050819	negative regulation of coagulation
0.35	GO:2000145	regulation of cell motility
0.35	GO:0001822	kidney development
0.35	GO:0043066	negative regulation of apoptotic process
0.34	GO:0006887	exocytosis

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.56	GO:0051059	NF-kappaB binding
0.55	GO:0048306	calcium-dependent protein binding
0.49	GO:0042802	identical protein binding
0.36	GO:0035374	chondroitin sulfate binding
0.35	GO:0004859	phospholipase inhibitor activity
0.35	GO:0008201	heparin binding
0.34	GO:0030246	carbohydrate binding

0.52	GO:0031965	nuclear membrane
0.52	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0012506	vesicle membrane
0.50	GO:0009986	cell surface
0.41	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0045177	apical part of cell
0.36	GO:0042583	chromaffin granule
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0098805	whole membrane

sp|P50996|ATP4A_CANLF
Potassium-transporting ATPase alpha chain 1
Search

ATP4A

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.83	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.74	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.71	GO:0006814	sodium ion transport
0.70	GO:0006813	potassium ion transport
0.63	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.57	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient
0.41	GO:0006885	regulation of pH
0.41	GO:0055075	potassium ion homeostasis
0.38	GO:0010155	regulation of proton transport
0.36	GO:0001696	gastric acid secretion

0.83	GO:0005391	sodium:potassium-exchanging ATPase activity
0.68	GO:0008900	potassium:proton exchanging ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.36	GO:0046982	protein heterodimerization activity

0.40	GO:0016323	basolateral plasma membrane
0.36	GO:0016324	apical plasma membrane
0.36	GO:0005615	extracellular space
0.34	GO:0005887	integral component of plasma membrane

0.83

GO:0005391

sp|P50997|AT1A1_CANLF
Sodium/potassium-transporting ATPase subunit alpha-1
Search

ATP1A1

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.54	GO:1903416	response to glycoside
0.53	GO:0006883	cellular sodium ion homeostasis
0.53	GO:0086009	membrane repolarization
0.53	GO:0031947	negative regulation of glucocorticoid biosynthetic process
0.52	GO:0045989	positive regulation of striated muscle contraction
0.52	GO:0045822	negative regulation of heart contraction

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0046872	metal ion binding
0.53	GO:1990239	steroid hormone binding
0.47	GO:0051087	chaperone binding
0.44	GO:0016791	phosphatase activity
0.38	GO:0030506	ankyrin binding

0.53	GO:0042383	sarcolemma
0.51	GO:0005890	sodium:potassium-exchanging ATPase complex
0.49	GO:0014069	postsynaptic density
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0043209	myelin sheath
0.49	GO:0016324	apical plasma membrane
0.41	GO:0043234	protein complex
0.38	GO:0014704	intercalated disc
0.37	GO:0005901	caveola
0.37	GO:0031410	cytoplasmic vesicle

0.85

GO:0005391

sp|P51147|RAB5C_CANLF
Ras-related protein Rab-5C
Search

RAB5C

0.93	Lysine acetyltransferase 2A

0.57	GO:0048227	plasma membrane to endosome transport
0.49	GO:0030100	regulation of endocytosis
0.41	GO:0007032	endosome organization
0.40	GO:0001702	gastrulation with mouth forming second
0.39	GO:0001525	angiogenesis
0.38	GO:0098609	cell-cell adhesion
0.38	GO:0019882	antigen processing and presentation
0.37	GO:0015031	protein transport
0.36	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0023014	signal transduction by protein phosphorylation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0030742	GTP-dependent protein binding
0.36	GO:0005216	ion channel activity
0.35	GO:0022832	voltage-gated channel activity
0.35	GO:0000155	phosphorelay sensor kinase activity
0.35	GO:0015079	potassium ion transmembrane transporter activity

0.54	GO:0005768	endosome
0.51	GO:0005811	lipid droplet
0.48	GO:0030139	endocytic vesicle
0.40	GO:0044433	cytoplasmic vesicle part
0.40	GO:0070062	extracellular exosome
0.40	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0042470	melanosome
0.38	GO:0005886	plasma membrane
0.38	GO:0070382	exocytic vesicle

0.35

EC:2.7.3

GO:0000155

sp|P51152|RAB12_CANLF
Ras-related protein Rab-12 (Fragment)
Search

RAB12

0.96	RAB12, member RAS oncogene family

0.54	GO:0008333	endosome to lysosome transport
0.53	GO:0071346	cellular response to interferon-gamma
0.53	GO:0016239	positive regulation of macroautophagy
0.48	GO:0044257	cellular protein catabolic process
0.38	GO:0006914	autophagy
0.37	GO:0015031	protein transport
0.33	GO:0032869	cellular response to insulin stimulus
0.33	GO:0017157	regulation of exocytosis
0.33	GO:0006904	vesicle docking involved in exocytosis
0.33	GO:0002790	peptide secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.54	GO:0055038	recycling endosome membrane
0.53	GO:0005776	autophagosome
0.53	GO:0045335	phagocytic vesicle
0.51	GO:0005764	lysosome
0.43	GO:0005794	Golgi apparatus
0.39	GO:0098852	lytic vacuole membrane
0.37	GO:0031984	organelle subcompartment
0.35	GO:0030141	secretory granule
0.34	GO:0005829	cytosol
0.33	GO:0005769	early endosome

sp|P51154|RB22A_CANLF
Ras-related protein Rab-22A
Search

RAB22A

0.97	Ras-related protein Rab-22A isoform B

0.58	GO:0097494	regulation of vesicle size
0.54	GO:0007032	endosome organization
0.53	GO:0006897	endocytosis
0.45	GO:0043001	Golgi to plasma membrane protein transport
0.45	GO:0090382	phagosome maturation
0.44	GO:0032869	cellular response to insulin stimulus
0.44	GO:0045055	regulated exocytosis
0.43	GO:0043112	receptor metabolic process
0.33	GO:0006662	glycerol ether metabolic process
0.33	GO:0045454	cell redox homeostasis

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0015035	protein disulfide oxidoreductase activity

0.58	GO:0045335	phagocytic vesicle
0.58	GO:0005769	early endosome
0.49	GO:0015629	actin cytoskeleton
0.45	GO:0032588	trans-Golgi network membrane
0.42	GO:0005886	plasma membrane
0.39	GO:0030666	endocytic vesicle membrane
0.38	GO:0005770	late endosome
0.38	GO:0001726	ruffle
0.37	GO:0070062	extracellular exosome
0.37	GO:0010008	endosome membrane

sp|P51666|NR4A1_CANLF
Nuclear receptor subfamily 4 group A member 1
Search

NR4A1

0.96	Orphan nuclear receptor HMR

0.80	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.64	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.60	GO:0045444	fat cell differentiation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0043066	negative regulation of apoptotic process
0.55	GO:0035914	skeletal muscle cell differentiation

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0046982	protein heterodimerization activity
0.50	GO:0035259	glucocorticoid receptor binding
0.50	GO:0042803	protein homodimerization activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.49	GO:0005829	cytosol
0.48	GO:0012505	endomembrane system
0.46	GO:0044446	intracellular organelle part
0.45	GO:0031090	organelle membrane
0.45	GO:0031975	envelope
0.42	GO:0070013	intracellular organelle lumen

sp|P51742|TNFA_CANLF
Tumor necrosis factor
Search

TNF

0.93	Tumor necrosis factor-alpha

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.71	GO:0097527	necroptotic signaling pathway
0.62	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.62	GO:0043507	positive regulation of JUN kinase activity
0.60	GO:0061048	negative regulation of branching involved in lung morphogenesis
0.60	GO:1904999	positive regulation of leukocyte adhesion to arterial endothelial cell
0.60	GO:0045994	positive regulation of translational initiation by iron
0.60	GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus
0.60	GO:0043243	positive regulation of protein complex disassembly

0.84	GO:0005164	tumor necrosis factor receptor binding
0.80	GO:0005125	cytokine activity
0.55	GO:0002020	protease binding
0.51	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0042802	identical protein binding

0.73	GO:0005615	extracellular space
0.57	GO:0001891	phagocytic cup
0.55	GO:0055037	recycling endosome
0.54	GO:0009897	external side of plasma membrane
0.54	GO:0098857	membrane microdomain
0.47	GO:0005887	integral component of plasma membrane
0.34	GO:0030141	secretory granule

sp|P52203|CCL2_CANLF
C-C motif chemokine 2
Search

0.75	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.66	GO:0097529	myeloid leukocyte migration
0.62	GO:0071674	mononuclear cell migration
0.61	GO:0071347	cellular response to interleukin-1
0.60	GO:0071356	cellular response to tumor necrosis factor
0.59	GO:0006954	inflammatory response
0.59	GO:2000501	regulation of natural killer cell chemotaxis
0.57	GO:0019221	cytokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.62	GO:0048020	CCR chemokine receptor binding
0.48	GO:0016004	phospholipase activator activity
0.41	GO:0046983	protein dimerization activity
0.40	GO:0004672	protein kinase activity
0.40	GO:0008201	heparin binding
0.35	GO:0005153	interleukin-8 receptor binding

0.71	GO:0005615	extracellular space
0.36	GO:0005622	intracellular

sp|P52204|PRPH2_CANLF
Peripherin-2
Search

PRPH2

0.97	Retinal degeneration, slow (Retinitis pigmentosa 7)

0.78	GO:0007601	visual perception
0.55	GO:0060041	retina development in camera-type eye
0.44	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0007155	cell adhesion
0.35	GO:1903525	regulation of membrane tubulation
0.35	GO:0009645	response to low light intensity stimulus
0.35	GO:0051289	protein homotetramerization
0.34	GO:0051258	protein polymerization

0.34	GO:0042803	protein homodimerization activity
0.34	GO:0015631	tubulin binding

0.56	GO:0001750	photoreceptor outer segment
0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0055037	recycling endosome
0.34	GO:0005795	Golgi stack
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0043234	protein complex

sp|P52206|GNA11_CANLF
Guanine nucleotide-binding protein subunit alpha-11 (Fragment)
Search

GNA11

0.88	Guanine nucleotide-binding protein subunit alpha-11

0.67	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0007603	phototransduction, visible light
0.48	GO:0009649	entrainment of circadian clock
0.48	GO:0001508	action potential
0.47	GO:0095500	acetylcholine receptor signaling pathway
0.47	GO:0045634	regulation of melanocyte differentiation
0.46	GO:0071467	cellular response to pH
0.45	GO:0048066	developmental pigmentation
0.44	GO:0001501	skeletal system development
0.44	GO:0007507	heart development

0.76	GO:0031683	G-protein beta/gamma-subunit complex binding
0.75	GO:0001664	G-protein coupled receptor binding
0.64	GO:0003924	GTPase activity
0.62	GO:0032550	purine ribonucleoside binding
0.62	GO:0019001	guanyl nucleotide binding
0.61	GO:0004871	signal transducer activity
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.37	GO:0046872	metal ion binding

0.49	GO:0001750	photoreceptor outer segment
0.44	GO:1905360	GTPase complex
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0098797	plasma membrane protein complex
0.38	GO:0005765	lysosomal membrane
0.38	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.39

GO:0047391

sp|P52211|PTHR_CANLF
Parathyroid hormone-related protein
Search

PTHLH

0.97	Parathyroid hormone like hormone

0.85	GO:0032330	regulation of chondrocyte differentiation
0.75	GO:0010469	regulation of receptor activity
0.61	GO:0061037	negative regulation of cartilage development
0.60	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.60	GO:0030819	positive regulation of cAMP biosynthetic process
0.56	GO:0045596	negative regulation of cell differentiation
0.56	GO:0001501	skeletal system development
0.52	GO:0002076	osteoblast development
0.44	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0042127	regulation of cell proliferation

0.79	GO:0005179	hormone activity
0.64	GO:0051428	peptide hormone receptor binding

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol

sp|P52212|PTHY_CANLF
Parathyroid hormone
Search

PTH

0.97	Parathyroid hormone

0.80	GO:0006874	cellular calcium ion homeostasis
0.80	GO:0046326	positive regulation of glucose import
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0090290	positive regulation of osteoclast proliferation
0.73	GO:0071866	negative regulation of apoptotic process in bone marrow
0.73	GO:0060732	positive regulation of inositol phosphate biosynthetic process
0.73	GO:0045725	positive regulation of glycogen biosynthetic process
0.72	GO:0071864	positive regulation of cell proliferation in bone marrow
0.72	GO:0007202	activation of phospholipase C activity
0.71	GO:0030819	positive regulation of cAMP biosynthetic process

0.79	GO:0005179	hormone activity
0.77	GO:0031856	parathyroid hormone receptor binding
0.72	GO:0051428	peptide hormone receptor binding
0.69	GO:0047485	protein N-terminus binding
0.68	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.66	GO:0005576	extracellular region
0.40	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P52784|PFKAM_CANLF
ATP-dependent 6-phosphofructokinase, muscle type
Search

PFKM

0.46	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.57	GO:0061718	glucose catabolic process to pyruvate
0.57	GO:0006735	NADH regeneration
0.55	GO:0046716	muscle cell cellular homeostasis
0.55	GO:0032024	positive regulation of insulin secretion
0.52	GO:0042593	glucose homeostasis
0.52	GO:0005980	glycogen catabolic process
0.50	GO:0046835	carbohydrate phosphorylation
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II

0.79	GO:0003872	6-phosphofructokinase activity
0.58	GO:0070061	fructose binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008022	protein C-terminus binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0019900	kinase binding
0.50	GO:0046872	metal ion binding
0.50	GO:0042803	protein homodimerization activity
0.37	GO:0070095	fructose-6-phosphate binding

0.57	GO:0005945	6-phosphofructokinase complex
0.55	GO:0097228	sperm principal piece
0.53	GO:0016324	apical plasma membrane
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.7.1.11

GO:0003872

sp|P54712|SODM_CANLF
Superoxide dismutase [Mn], mitochondrial (Fragment)
Search

0.10	Superoxide dismutase [Mn], mitochondrial (Fragment)

0.76	GO:0071450	cellular response to oxygen radical
0.76	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.59	GO:0001306	age-dependent response to oxidative stress
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0003070	regulation of systemic arterial blood pressure by neurotransmitter
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0048773	erythrophore differentiation
0.49	GO:0003085	negative regulation of systemic arterial blood pressure

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.40	GO:0042802	identical protein binding
0.40	GO:0019825	oxygen binding
0.38	GO:0019899	enzyme binding
0.35	GO:0003677	DNA binding

0.50	GO:0005759	mitochondrial matrix
0.45	GO:0043209	myelin sheath
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.39	GO:0009295	nucleoid
0.38	GO:0070062	extracellular exosome
0.36	GO:0043232	intracellular non-membrane-bounded organelle

0.77

EC:1.15.1.1

GO:0004784

sp|P54713|NDUAA_CANLF
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10 (Fragment)
Search

0.10	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10 (Fragment)

0.30	GO:0033108	mitochondrial respiratory chain complex assembly
0.30	GO:0055114	oxidation-reduction process
0.30	GO:0010257	NADH dehydrogenase complex assembly
0.30	GO:0097031	mitochondrial respiratory chain complex I biogenesis

0.30	GO:0030964	NADH dehydrogenase complex
0.30	GO:0044422	organelle part
0.30	GO:0031975	envelope
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0005737	cytoplasm
0.30	GO:1990204	oxidoreductase complex
0.30	GO:0070469	respiratory chain
0.30	GO:0043234	protein complex
0.30	GO:0043229	intracellular organelle

sp|P54714|TPIS_CANLF
Triosephosphate isomerase
Search

TPI1

0.47	Triosephosphate isomerase

0.73	GO:0019319	hexose biosynthetic process
0.72	GO:0006098	pentose-phosphate shunt
0.71	GO:0006006	glucose metabolic process
0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.50	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.45	GO:0046174	polyol catabolic process
0.45	GO:0006071	glycerol metabolic process
0.45	GO:0007275	multicellular organism development

0.78	GO:0004807	triose-phosphate isomerase activity
0.48	GO:0031625	ubiquitin protein ligase binding

0.43	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.78	EC:5.3.1.1	GO:0004807
0.78	KEGG:R01015	GO:0004807

sp|P54804|GALC_CANLF
Galactocerebrosidase
Search

GALC

0.93	galactocerebrosidase precursor

0.86	GO:0006683	galactosylceramide catabolic process
0.34	GO:0045859	regulation of protein kinase activity

0.86	GO:0004336	galactosylceramidase activity
0.35	GO:0019887	protein kinase regulator activity

0.46	GO:0005764	lysosome
0.44	GO:0005739	mitochondrion
0.38	GO:0070062	extracellular exosome
0.35	GO:0005775	vacuolar lumen
0.35	GO:0005956	protein kinase CK2 complex
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:3.2.1.46

GO:0004336

sp|P54827|CNRG_CANLF
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Search

PDE6G

0.96	Retinal rod rhodopsin-sensitive cgmp 3'5'-cyclic phosphodiesterase subunit gamma

0.77	GO:0007601	visual perception
0.52	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.52	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.50	GO:0000187	activation of MAPK activity
0.38	GO:0050896	response to stimulus
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0043086	negative regulation of catalytic activity
0.35	GO:0198738	cell-cell signaling by wnt

0.85	GO:0030553	cGMP binding
0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.39	GO:0030507	spectrin binding
0.36	GO:0004857	enzyme inhibitor activity
0.34	GO:0008270	zinc ion binding

0.38	GO:0097381	photoreceptor disc membrane
0.36	GO:0042622	photoreceptor outer segment membrane

0.78

GO:0004114

sp|P54828|TSHB_CANLF
Thyrotropin subunit beta
Search

TSHB

0.88	Thyroid stimulating hormone beta subunit

0.76	GO:0010469	regulation of receptor activity
0.40	GO:0010033	response to organic substance
0.39	GO:0071495	cellular response to endogenous stimulus
0.39	GO:0007267	cell-cell signaling
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0033273	response to vitamin
0.37	GO:0043627	response to estrogen
0.37	GO:0051592	response to calcium ion
0.37	GO:0070887	cellular response to chemical stimulus

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|P54831|TGFB1_CANLF
Transforming growth factor beta-1
Search

TGFB1

0.92	Transforming growth factor beta

0.79	GO:0016049	cell growth
0.77	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.76	GO:1901664	regulation of NAD+ ADP-ribosyltransferase activity
0.76	GO:0043932	ossification involved in bone remodeling
0.75	GO:0048298	positive regulation of isotype switching to IgA isotypes
0.75	GO:0007182	common-partner SMAD protein phosphorylation
0.75	GO:0010936	negative regulation of macrophage cytokine production
0.75	GO:0007183	SMAD protein complex assembly
0.75	GO:0010763	positive regulation of fibroblast migration
0.74	GO:0032740	positive regulation of interleukin-17 production

0.84	GO:0005160	transforming growth factor beta receptor binding
0.75	GO:0008083	growth factor activity
0.71	GO:0003823	antigen binding
0.58	GO:0043539	protein serine/threonine kinase activator activity
0.53	GO:0042802	identical protein binding
0.51	GO:0019899	enzyme binding
0.48	GO:0005125	cytokine activity
0.41	GO:0047485	protein N-terminus binding
0.39	GO:0046982	protein heterodimerization activity
0.34	GO:0001540	amyloid-beta binding

0.72	GO:0005615	extracellular space
0.63	GO:0009986	cell surface
0.61	GO:0005902	microvillus
0.56	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.38	GO:0097708	intracellular vesicle
0.37	GO:0012505	endomembrane system

sp|P54832|PON2_CANLF
Serum paraoxonase/arylesterase 2
Search

PON2

0.92	Serum paraoxonase/arylesterase 2

0.44	GO:0009636	response to toxic substance
0.44	GO:0019439	aromatic compound catabolic process
0.43	GO:0010875	positive regulation of cholesterol efflux
0.42	GO:0032411	positive regulation of transporter activity
0.42	GO:0051099	positive regulation of binding
0.42	GO:0008203	cholesterol metabolic process
0.42	GO:0046470	phosphatidylcholine metabolic process
0.41	GO:0016311	dephosphorylation
0.41	GO:1902617	response to fluoride
0.40	GO:0070542	response to fatty acid

0.85	GO:0004064	arylesterase activity
0.50	GO:0102007	acyl-L-homoserine-lactone lactonohydrolase activity
0.48	GO:0004063	aryldialkylphosphatase activity
0.46	GO:0042802	identical protein binding
0.40	GO:0005543	phospholipid binding
0.40	GO:0005509	calcium ion binding
0.39	GO:0046983	protein dimerization activity
0.36	GO:0008035	high-density lipoprotein particle binding
0.34	GO:0016209	antioxidant activity

0.61	GO:0005576	extracellular region
0.43	GO:1990777	lipoprotein particle
0.40	GO:0005764	lysosome
0.37	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.36	GO:0005739	mitochondrion
0.36	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

0.85

EC:3.1.1.2

GO:0004064

sp|P54833|ADRB2_CANLF
Beta-2 adrenergic receptor
Search

ADRB2

0.87	Beta-2 adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.85	GO:0006940	regulation of smooth muscle contraction
0.84	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.82	GO:0097746	regulation of blood vessel diameter
0.54	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin
0.52	GO:0007190	activation of adenylate cyclase activity
0.51	GO:1904502	regulation of lipophagy
0.51	GO:1901098	positive regulation of autophagosome maturation
0.50	GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine
0.50	GO:0061885	positive regulation of mini excitatory postsynaptic potential

0.86	GO:0004941	beta2-adrenergic receptor activity
0.53	GO:0051380	norepinephrine binding
0.49	GO:0008179	adenylate cyclase binding
0.48	GO:0015459	potassium channel regulator activity
0.47	GO:0001540	amyloid-beta binding
0.47	GO:0042803	protein homodimerization activity
0.46	GO:0051379	epinephrine binding
0.44	GO:0032403	protein complex binding
0.36	GO:0031713	B2 bradykinin receptor binding
0.36	GO:0090722	receptor-receptor interaction

0.48	GO:0043235	receptor complex
0.46	GO:0016324	apical plasma membrane
0.45	GO:0005769	early endosome
0.42	GO:0005887	integral component of plasma membrane
0.40	GO:0005634	nucleus
0.36	GO:0032809	neuronal cell body membrane
0.35	GO:0098805	whole membrane
0.35	GO:0043197	dendritic spine
0.35	GO:0042383	sarcolemma
0.35	GO:0030424	axon

sp|P54834|TYRO_CANLF
Tyrosinase
Search

TYR

0.61	Truncated tyrosinase

0.58	GO:0042438	melanin biosynthetic process
0.56	GO:0048538	thymus development
0.54	GO:0043473	pigmentation
0.53	GO:0008283	cell proliferation
0.51	GO:0055114	oxidation-reduction process
0.42	GO:0033280	response to vitamin D
0.42	GO:0051591	response to cAMP
0.41	GO:0009411	response to UV
0.35	GO:0007601	visual perception
0.35	GO:0006570	tyrosine metabolic process

0.69	GO:0004503	monophenol monooxygenase activity
0.52	GO:0046872	metal ion binding
0.51	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity

0.58	GO:0042470	melanosome
0.53	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0090741	pigment granule membrane
0.42	GO:0045009	chitosome
0.42	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0098805	whole membrane
0.38	GO:0005829	cytosol
0.35	GO:0005798	Golgi-associated vesicle
0.30	GO:0016021	integral component of membrane

0.69

EC:1.14.18.1

GO:0004503

sp|P54835|EFTU_CANLF
Elongation factor Tu, mitochondrial (Fragment)
Search

0.10	Elongation factor Tu, mitochondrial (Fragment)

0.30	GO:0044237	cellular metabolic process
0.30	GO:0006807	nitrogen compound metabolic process
0.30	GO:0010467	gene expression
0.30	GO:1901576	organic substance biosynthetic process
0.30	GO:0044238	primary metabolic process

0.30	GO:0032550	purine ribonucleoside binding
0.30	GO:0043167	ion binding
0.30	GO:0019001	guanyl nucleotide binding
0.30	GO:0003746	translation elongation factor activity
0.30	GO:0032555	purine ribonucleotide binding

0.30	GO:0005737	cytoplasm
0.30	GO:0043231	intracellular membrane-bounded organelle

sp|P54836|IDH3A_CANLF
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (Fragment)
Search

0.10	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (Fragment)

0.30	GO:0072350	tricarboxylic acid metabolic process
0.30	GO:0009060	aerobic respiration
0.30	GO:0044238	primary metabolic process

0.30	GO:0004448	isocitrate dehydrogenase activity
0.30	GO:0046872	metal ion binding

0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0005737	cytoplasm
0.30	GO:0043229	intracellular organelle

0.30

EC:1.1.1

GO:0004448

sp|P55261|CBPB1_CANLF
Carboxypeptidase B
Search

CPB1

0.79	Pancreatic carboxypeptidase B

0.59	GO:0006508	proteolysis
0.42	GO:0002002	regulation of angiotensin levels in blood
0.35	GO:0071466	cellular response to xenobiotic stimulus
0.34	GO:0042730	fibrinolysis

0.75	GO:0004181	metallocarboxypeptidase activity
0.61	GO:0008270	zinc ion binding

0.47

GO:0044421

extracellular region part

0.75

EC:3.4.17

GO:0004181

sp|P55745|RAB21_CANLF
Ras-related protein Rab-21
Search

RAB21

0.95	RAB21, member RAS oncogene family

0.54	GO:2000643	positive regulation of early endosome to late endosome transport
0.54	GO:0030100	regulation of endocytosis
0.53	GO:0050775	positive regulation of dendrite morphogenesis
0.50	GO:0017157	regulation of exocytosis
0.41	GO:0008089	anterograde axonal transport
0.40	GO:0030516	regulation of axon extension
0.37	GO:0015031	protein transport
0.32	GO:0043547	positive regulation of GTPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding
0.32	GO:0005096	GTPase activator activity

0.55	GO:0098559	cytoplasmic side of early endosome membrane
0.50	GO:0032580	Golgi cisterna membrane
0.49	GO:0005802	trans-Golgi network
0.49	GO:0012506	vesicle membrane
0.49	GO:0043005	neuron projection
0.48	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0032154	cleavage furrow
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005925	focal adhesion

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P56497|EDNRB_CANLF
Endothelin B receptor
Search

EDNRB

0.97	Endothelin receptor type B

0.82	GO:0086100	endothelin receptor signaling pathway
0.81	GO:0048484	enteric nervous system development
0.79	GO:0042310	vasoconstriction
0.77	GO:0008217	regulation of blood pressure
0.61	GO:0035645	enteric smooth muscle cell differentiation
0.61	GO:0007497	posterior midgut development
0.60	GO:0014043	negative regulation of neuron maturation
0.59	GO:0050931	pigment cell differentiation
0.59	GO:0048246	macrophage chemotaxis
0.59	GO:0014821	phasic smooth muscle contraction

0.83	GO:0004962	endothelin receptor activity
0.58	GO:0017046	peptide hormone binding
0.42	GO:0031702	type 1 angiotensin receptor binding

0.43	GO:0005886	plasma membrane
0.39	GO:0098857	membrane microdomain
0.39	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

sp|P56513|PLM_CANLF
Phospholemman
Search

FXYD1

0.78	FXYD domain-containing ion transport regulator

0.62	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.61	GO:1903278	positive regulation of sodium ion export across plasma membrane
0.61	GO:0086036	regulation of cardiac muscle cell membrane potential
0.60	GO:0034220	ion transmembrane transport
0.36	GO:0051414	response to cortisol
0.36	GO:0042538	hyperosmotic salinity response
0.36	GO:0060416	response to growth hormone

0.70	GO:0005216	ion channel activity
0.62	GO:0017080	sodium channel regulator activity
0.36	GO:0051117	ATPase binding

0.57	GO:0042383	sarcolemma
0.42	GO:0005887	integral component of plasma membrane

sp|P56535|UHA3_CANLF
Unknown protein from spot 7520 of 2D-PAGE of heart tissue (Fragment)
Search

sp|P56590|CP1A1_CANLF
Cytochrome P450 1A1
Search

sp|P56592|CP1A2_CANLF
Cytochrome P450 1A2
Search

sp|P56594|CP2CL_CANLF
Cytochrome P450 2C21 (Fragment)
Search

0.95	Cytochrome P450 family 2 subfamily C member 9

0.59	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.46	GO:0042738	exogenous drug catabolic process
0.44	GO:0043651	linoleic acid metabolic process
0.42	GO:0002933	lipid hydroxylation
0.42	GO:0008202	steroid metabolic process
0.41	GO:0070988	demethylation
0.41	GO:0016098	monoterpenoid metabolic process
0.37	GO:0006805	xenobiotic metabolic process
0.35	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0034875	caffeine oxidase activity
0.37	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding

0.45	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P56595|APOC1_CANLF
Apolipoprotein C-I
Search

APOC1

0.97	Apolipoprotein C-I, acidic form

0.75	GO:0042157	lipoprotein metabolic process
0.68	GO:0006869	lipid transport
0.65	GO:0010900	negative regulation of phosphatidylcholine catabolic process
0.63	GO:0034447	very-low-density lipoprotein particle clearance
0.63	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.63	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.62	GO:0051005	negative regulation of lipoprotein lipase activity
0.62	GO:0010985	negative regulation of lipoprotein particle clearance
0.62	GO:0032375	negative regulation of cholesterol transport
0.61	GO:0048261	negative regulation of receptor-mediated endocytosis

0.60	GO:0004859	phospholipase inhibitor activity
0.60	GO:0005504	fatty acid binding
0.39	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.38	GO:0031210	phosphatidylcholine binding

0.69	GO:0034361	very-low-density lipoprotein particle
0.59	GO:0034364	high-density lipoprotein particle
0.50	GO:0005783	endoplasmic reticulum
0.40	GO:0070062	extracellular exosome
0.38	GO:0042627	chylomicron

sp|P56950|MDM2_CANLF
E3 ubiquitin-protein ligase Mdm2
Search

MDM2

0.92	E3 ubiquitin-protein ligase Mdm2 isoform C

0.85	GO:0071157	negative regulation of cell cycle arrest
0.76	GO:0043066	negative regulation of apoptotic process
0.76	GO:0000122	negative regulation of transcription by RNA polymerase II
0.71	GO:0016567	protein ubiquitination
0.57	GO:0072717	cellular response to actinomycin D
0.56	GO:1990000	amyloid fibril formation
0.55	GO:0007089	traversing start control point of mitotic cell cycle
0.55	GO:0003283	atrial septum development
0.55	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.55	GO:0003181	atrioventricular valve morphogenesis

0.57	GO:0061663	NEDD8 ligase activity
0.55	GO:0016874	ligase activity
0.55	GO:0097110	scaffold protein binding
0.54	GO:0097718	disordered domain specific binding
0.54	GO:0002039	p53 binding
0.53	GO:0047485	protein N-terminus binding
0.52	GO:0008097	5S rRNA binding
0.52	GO:0046872	metal ion binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0043021	ribonucleoprotein complex binding

0.60	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.42	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm
0.39	GO:0045202	synapse
0.35	GO:0005886	plasma membrane
0.35	GO:0012506	vesicle membrane
0.34	GO:0097708	intracellular vesicle

0.55

GO:0016874

sp|P58027|AOFA_CANLF
Amine oxidase [flavin-containing] A
Search

MAOA

0.48	Amine oxidase [flavin-containing] A

0.55	GO:0042420	dopamine catabolic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0042135	neurotransmitter catabolic process
0.38	GO:0014063	negative regulation of serotonin secretion
0.38	GO:0010269	response to selenium ion
0.38	GO:0045915	positive regulation of catecholamine metabolic process
0.38	GO:0051412	response to corticosterone
0.38	GO:0010044	response to aluminum ion
0.38	GO:0042053	regulation of dopamine metabolic process
0.37	GO:0045471	response to ethanol

0.54	GO:0016491	oxidoreductase activity
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0051378	serotonin binding

0.48	GO:0005739	mitochondrion
0.45	GO:0031967	organelle envelope
0.45	GO:0031090	organelle membrane
0.43	GO:0098805	whole membrane
0.41	GO:0019867	outer membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.54

GO:0016491

sp|P60058|SC61G_CANLF
Protein transport protein Sec61 subunit gamma
Search

SEC61G

0.96	Transport protein Sec61 subunit gamma

0.71	GO:0006605	protein targeting
0.70	GO:0071806	protein transmembrane transport
0.41	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.39	GO:0001555	oocyte growth
0.38	GO:0030728	ovulation
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0016310	phosphorylation
0.34	GO:0022406	membrane docking
0.33	GO:0007275	multicellular organism development

0.75	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.35	GO:0016301	kinase activity
0.34	GO:0005543	phospholipid binding
0.33	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0044422	organelle part
0.36	GO:0043227	membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|P60467|SC61B_CANLF
Protein transport protein Sec61 subunit beta
Search

SEC61B

0.75	Transport protein Sec61 subunit beta (Fragment)

0.69	GO:0006886	intracellular protein transport
0.54	GO:1903513	endoplasmic reticulum to cytosol transport
0.51	GO:0030433	ubiquitin-dependent ERAD pathway
0.51	GO:0006606	protein import into nucleus
0.46	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.45	GO:0090150	establishment of protein localization to membrane
0.44	GO:0071806	protein transmembrane transport
0.43	GO:0065009	regulation of molecular function
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0051103	DNA ligation involved in DNA repair

0.56	GO:0048408	epidermal growth factor binding
0.48	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.46	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.35	GO:0043022	ribosome binding
0.34	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.34	GO:0003723	RNA binding
0.34	GO:0003910	DNA ligase (ATP) activity
0.34	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.33	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.85	GO:0005784	Sec61 translocon complex
0.51	GO:0031205	endoplasmic reticulum Sec complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004675

sp|P60483|PTEN_CANLF
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Search

PTEN

0.83	Phosphatase and tensin homolog A

0.86	GO:0051895	negative regulation of focal adhesion assembly
0.85	GO:0051898	negative regulation of protein kinase B signaling
0.83	GO:0030336	negative regulation of cell migration
0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.80	GO:0046855	inositol phosphate dephosphorylation
0.79	GO:0008285	negative regulation of cell proliferation
0.79	GO:0031647	regulation of protein stability
0.78	GO:2000808	negative regulation of synaptic vesicle clustering
0.77	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.76	GO:1903689	regulation of wound healing, spreading of epidermal cells

0.87	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
0.87	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
0.85	GO:0030165	PDZ domain binding
0.79	GO:0051717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.74	GO:1990381	ubiquitin-specific protease binding
0.73	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.70	GO:0010997	anaphase-promoting complex binding
0.65	GO:0019901	protein kinase binding

0.75	GO:0035749	myelin sheath adaxonal region
0.74	GO:0043220	Schmidt-Lanterman incisure
0.68	GO:0016324	apical plasma membrane
0.65	GO:0043005	neuron projection
0.64	GO:0009898	cytoplasmic side of plasma membrane
0.60	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol
0.38	GO:0036477	somatodendritic compartment
0.38	GO:0045211	postsynaptic membrane
0.38	GO:0120038	plasma membrane bounded cell projection part

0.87

EC:3.1.3.67

GO:0016314

sp|P60524|HBB_CANLF
Hemoglobin subunit beta
Search

HBB

0.61	Hemoglobin subunit delta

0.79	GO:0015671	oxygen transport
0.44	GO:0070293	renal absorption
0.43	GO:0051291	protein heterooligomerization
0.42	GO:0042542	response to hydrogen peroxide
0.41	GO:0010942	positive regulation of cell death
0.41	GO:0042744	hydrogen peroxide catabolic process
0.39	GO:0098869	cellular oxidant detoxification
0.35	GO:0030185	nitric oxide transport
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070527	platelet aggregation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0031720	haptoglobin binding
0.44	GO:0030492	hemoglobin binding
0.40	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.45	GO:0031838	haptoglobin-hemoglobin complex
0.40	GO:0005615	extracellular space
0.35	GO:0071682	endocytic vesicle lumen
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:1903561	extracellular vesicle

0.40	EC:1.11.1.7	GO:0004601
0.40	KEGG:R03532	GO:0004601

sp|P60529|HBA_CANLF
Hemoglobin subunit alpha
Search

HBA

0.60	Hemoglobin subunit alpha

0.79	GO:0015671	oxygen transport
0.36	GO:0051291	protein heterooligomerization
0.36	GO:0042542	response to hydrogen peroxide
0.35	GO:0010942	positive regulation of cell death
0.35	GO:0042744	hydrogen peroxide catabolic process
0.35	GO:0098869	cellular oxidant detoxification
0.35	GO:0035634	response to stilbenoid
0.35	GO:0015701	bicarbonate transport
0.34	GO:0048821	erythrocyte development
0.34	GO:0001701	in utero embryonic development

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.39	GO:0031720	haptoglobin binding
0.36	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.39	GO:0031838	haptoglobin-hemoglobin complex
0.37	GO:0022627	cytosolic small ribosomal subunit
0.36	GO:0005615	extracellular space
0.35	GO:0071682	endocytic vesicle lumen
0.34	GO:0043209	myelin sheath
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.36	EC:1.11.1.7	GO:0004601
0.36	KEGG:R03532	GO:0004601

sp|P60952|CDC42_CANLF
Cell division control protein 42 homolog
Search

CDC42

0.83	Cell division control protein 42

0.75	GO:0007264	small GTPase mediated signal transduction
0.60	GO:0051301	cell division
0.54	GO:0046847	filopodium assembly
0.53	GO:0038189	neuropilin signaling pathway
0.53	GO:0071338	positive regulation of hair follicle cell proliferation
0.53	GO:0051489	regulation of filopodium assembly
0.52	GO:0060684	epithelial-mesenchymal cell signaling
0.52	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.52	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly
0.51	GO:0048664	neuron fate determination

0.66	GO:0003924	GTPase activity
0.64	GO:0005525	GTP binding
0.53	GO:0051022	Rho GDP-dissociation inhibitor binding
0.52	GO:0032427	GBD domain binding
0.51	GO:0034191	apolipoprotein A-I receptor binding
0.51	GO:0030742	GTP-dependent protein binding
0.50	GO:0031996	thioesterase binding
0.47	GO:0019901	protein kinase binding
0.46	GO:0061630	ubiquitin protein ligase activity
0.45	GO:0042802	identical protein binding

0.50	GO:0031256	leading edge membrane
0.49	GO:0051233	spindle midzone
0.49	GO:0045335	phagocytic vesicle
0.49	GO:0030496	midbody
0.49	GO:0043197	dendritic spine
0.48	GO:0043209	myelin sheath
0.48	GO:0030175	filopodium
0.48	GO:0072686	mitotic spindle
0.48	GO:0045177	apical part of cell
0.47	GO:0000322	storage vacuole

0.34

GO:0004674

sp|P61007|RAB8A_CANLF
Ras-related protein Rab-8A
Search

RAB8A

0.92	Oncogene c-mel

0.58	GO:0048210	Golgi vesicle fusion to target membrane
0.54	GO:0006904	vesicle docking involved in exocytosis
0.52	GO:0060271	cilium assembly
0.50	GO:0010506	regulation of autophagy
0.49	GO:0072659	protein localization to plasma membrane
0.47	GO:0017157	regulation of exocytosis
0.45	GO:0048666	neuron development
0.44	GO:0009306	protein secretion
0.43	GO:0032402	melanosome transport
0.43	GO:0032869	cellular response to insulin stimulus

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.56	GO:0031489	myosin V binding
0.56	GO:0019003	GDP binding
0.40	GO:0017137	Rab GTPase binding
0.38	GO:0019901	protein kinase binding
0.36	GO:0071532	ankyrin repeat binding
0.36	GO:0032794	GTPase activating protein binding
0.35	GO:0030911	TPR domain binding
0.35	GO:0005102	receptor binding

0.56	GO:0055038	recycling endosome membrane
0.55	GO:0045335	phagocytic vesicle
0.54	GO:0097546	ciliary base
0.53	GO:0097730	non-motile cilium
0.53	GO:0030133	transport vesicle
0.52	GO:0036064	ciliary basal body
0.51	GO:0005813	centrosome
0.51	GO:0030136	clathrin-coated vesicle
0.50	GO:0005798	Golgi-associated vesicle
0.48	GO:0030667	secretory granule membrane

sp|P61008|SPCS3_CANLF
Signal peptidase complex subunit 3
Search

SPCS3

0.93	Signal peptidase complex subunit 3

0.76	GO:0006465	signal peptide processing
0.44	GO:0045047	protein targeting to ER

0.59

GO:0008233

peptidase activity

0.79	GO:0005787	signal peptidase complex
0.37	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.59

GO:0008233

sp|P61010|SRP54_CANLF
Signal recognition particle 54 kDa protein
Search

SRP54

0.62	Signal recognition particle 54 kDa protein (Fragment)

0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.47	GO:0042493	response to drug
0.35	GO:0065002	intracellular protein transmembrane transport
0.35	GO:0043623	cellular protein complex assembly

0.78	GO:0008312	7S RNA binding
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0030942	endoplasmic reticulum signal peptide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0043021	ribonucleoprotein complex binding
0.40	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.80	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle

sp|P61012|PPLA_CANLF
Cardiac phospholamban
Search

PLN

0.97	Cardiac phospholamban

0.77	GO:0006816	calcium ion transport
0.72	GO:0043086	negative regulation of catalytic activity
0.69	GO:1901877	negative regulation of calcium ion binding
0.68	GO:0086023	adrenergic receptor signaling pathway involved in heart process
0.68	GO:0086092	regulation of the force of heart contraction by cardiac conduction
0.66	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.66	GO:1901894	regulation of calcium-transporting ATPase activity
0.66	GO:1901077	regulation of relaxation of muscle
0.65	GO:0010459	negative regulation of heart rate
0.65	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity

0.85	GO:0005246	calcium channel regulator activity
0.82	GO:0042030	ATPase inhibitor activity
0.39	GO:0051117	ATPase binding
0.37	GO:0042802	identical protein binding

0.83	GO:0033017	sarcoplasmic reticulum membrane
0.68	GO:0090534	calcium ion-transporting ATPase complex
0.59	GO:0031966	mitochondrial membrane
0.39	GO:0031982	vesicle
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0043234	protein complex

sp|P61017|RAB4B_CANLF
Ras-related protein Rab-4B
Search

RAB4B

0.76	RAB4A, member RAS oncogene family variant (Fragment)

0.51	GO:0030100	regulation of endocytosis
0.50	GO:0001944	vasculature development
0.46	GO:0019882	antigen processing and presentation
0.42	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0008565	protein transporter activity

0.48	GO:0005768	endosome
0.48	GO:0070062	extracellular exosome
0.48	GO:0032593	insulin-responsive compartment
0.47	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|P61105|RAB2A_CANLF
Ras-related protein Rab-2A
Search

RAB2A

0.95	RAB2, member RAS oncogene family

0.63

GO:0007030

Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58

GO:0005794

Golgi apparatus

sp|P61162|ACTZ_CANLF
Alpha-centractin
Search

ACTR1A

0.90	Alpha-centractin

0.37	GO:0007283	spermatogenesis
0.37	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0006888	ER to Golgi vesicle-mediated transport

0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.82	GO:0005869	dynactin complex
0.56	GO:0005813	centrosome
0.53	GO:0099738	cell cortex region
0.52	GO:0043209	myelin sheath
0.38	GO:0002177	manchette
0.38	GO:0070062	extracellular exosome
0.37	GO:0005814	centriole
0.37	GO:0030137	COPI-coated vesicle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

sp|P61797|APTX_CANLF
Aprataxin
Search

APTX

0.94

Aprataxin

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.54	GO:0042542	response to hydrogen peroxide
0.51	GO:0031647	regulation of protein stability
0.49	GO:0006266	DNA ligation
0.47	GO:0016311	dephosphorylation

0.85	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity
0.55	GO:0003677	DNA binding
0.54	GO:0047485	protein N-terminus binding
0.54	GO:0051219	phosphoprotein binding
0.53	GO:0008967	phosphoglycolate phosphatase activity
0.51	GO:0003682	chromatin binding
0.50	GO:0003725	double-stranded RNA binding
0.49	GO:0120108	DNA-3'-diphospho-5'-guanosine diphosphatase
0.39	GO:0046403	polynucleotide 3'-phosphatase activity
0.37	GO:0046872	metal ion binding

0.52	GO:0005730	nucleolus
0.50	GO:0000790	nuclear chromatin
0.50	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm

0.53	EC:3.1.3.18	GO:0008967
0.53	KEGG:R01334	GO:0008967

sp|P61900|CX6A2_CANLF
Cytochrome c oxidase subunit 6A2, mitochondrial (Fragment)
Search

0.87	Cytochrome c oxidase subunit 6A2, mitochondrial (Fragment)

0.70	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen
0.58	GO:1902600	hydrogen ion transmembrane transport
0.57	GO:0050790	regulation of catalytic activity

0.60	GO:0015002	heme-copper terminal oxidase activity
0.60	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.58	GO:0015078	hydrogen ion transmembrane transporter activity
0.58	GO:0030234	enzyme regulator activity
0.57	GO:0009055	electron transfer activity

0.76	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.60

EC:1.9.3

GO:0016676

sp|P61902|CX6A1_CANLF
Cytochrome c oxidase subunit 6A1, mitochondrial (Fragment)
Search

COX6A1

0.92	Cytochrome c oxidase subunit 6A1, mitochondrial (Fragment)

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.46	GO:0050790	regulation of catalytic activity
0.44	GO:0006119	oxidative phosphorylation
0.44	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.47	GO:0030234	enzyme regulator activity

0.83	GO:0005751	mitochondrial respiratory chain complex IV
0.40	GO:0043209	myelin sheath
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9

GO:0016675

sp|P61904|COX8B_CANLF
Cytochrome c oxidase subunit 8B, mitochondrial (Fragment)
Search

0.10	Cytochrome c oxidase subunit 8B, mitochondrial (Fragment)

0.30	GO:0031975	envelope
0.30	GO:0005737	cytoplasm
0.30	GO:0031090	organelle membrane
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044446	intracellular organelle part

sp|P61905|COX8A_CANLF
Cytochrome c oxidase subunit 8A, mitochondrial (Fragment)
Search

0.10	Cytochrome c oxidase subunit 8A, mitochondrial (Fragment)

0.30	GO:0031975	envelope
0.30	GO:0005737	cytoplasm
0.30	GO:0031090	organelle membrane
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044446	intracellular organelle part

sp|P62286|ASPM_CANLF
Abnormal spindle-like microcephaly-associated protein homolog
Search

ASPM

0.66	Abnormal spindle microtubule assembly

0.80	GO:0007051	spindle organization
0.59	GO:0045769	negative regulation of asymmetric cell division
0.57	GO:0051661	maintenance of centrosome location
0.57	GO:0021873	forebrain neuroblast division
0.56	GO:0002052	positive regulation of neuroblast proliferation
0.56	GO:0097150	neuronal stem cell population maintenance
0.54	GO:0051653	spindle localization
0.54	GO:0021987	cerebral cortex development
0.54	GO:0008584	male gonad development
0.54	GO:0090263	positive regulation of canonical Wnt signaling pathway

0.56	GO:0005516	calmodulin binding
0.36	GO:0019901	protein kinase binding

0.57	GO:0036449	microtubule minus-end
0.56	GO:0097431	mitotic spindle pole
0.55	GO:0072687	meiotic spindle
0.53	GO:0030496	midbody
0.47	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.36	GO:0016324	apical plasma membrane
0.36	GO:0005813	centrosome
0.30	GO:0016021	integral component of membrane

sp|P62490|RB11A_CANLF
Ras-related protein Rab-11A
Search

RAB11A

0.88	Novel protein similar to vertebrate Ras family

0.66	GO:0032402	melanosome transport
0.57	GO:0006887	exocytosis
0.57	GO:0010796	regulation of multivesicular body size
0.57	GO:0060627	regulation of vesicle-mediated transport
0.57	GO:0097734	extracellular exosome biogenesis
0.56	GO:0030953	astral microtubule organization
0.56	GO:0036258	multivesicular body assembly
0.56	GO:0045773	positive regulation of axon extension
0.55	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.54	GO:0007080	mitotic metaphase plate congression

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.62	GO:0031489	myosin V binding
0.49	GO:0008017	microtubule binding
0.49	GO:0019003	GDP binding
0.47	GO:0045296	cadherin binding
0.34	GO:0019905	syntaxin binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0016874	ligase activity

0.62	GO:0055037	recycling endosome
0.60	GO:0045335	phagocytic vesicle
0.55	GO:0005771	multivesicular body
0.55	GO:0032154	cleavage furrow
0.54	GO:0005828	kinetochore microtubule
0.53	GO:0070062	extracellular exosome
0.52	GO:0030424	axon
0.52	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005802	trans-Golgi network
0.52	GO:0000922	spindle pole

0.33

GO:0016874

sp|P62822|RAB1A_CANLF
Ras-related protein Rab-1A
Search

RAB1A

0.86	Ras-associated binding-GTPase 1a4

0.53	GO:0072606	interleukin-8 secretion
0.53	GO:0030252	growth hormone secretion
0.52	GO:0032402	melanosome transport
0.51	GO:0034446	substrate adhesion-dependent cell spreading
0.51	GO:0090110	cargo loading into COPII-coated vesicle
0.51	GO:1903020	positive regulation of glycoprotein metabolic process
0.50	GO:0047496	vesicle transport along microtubule
0.49	GO:0000045	autophagosome assembly
0.49	GO:0016477	cell migration
0.48	GO:0007030	Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045296	cadherin binding

0.51	GO:0042470	melanosome
0.49	GO:0000139	Golgi membrane
0.43	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005769	early endosome
0.37	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0030133	transport vesicle
0.34	GO:0043025	neuronal cell body
0.34	GO:0099503	secretory vesicle
0.34	GO:0098793	presynapse

sp|P62825|RAN_CANLF
GTP-binding nuclear protein Ran
Search

RAN

0.69	GTP-binding nuclear protein Ran

0.72	GO:0006913	nucleocytoplasmic transport
0.65	GO:0015031	protein transport
0.52	GO:0051030	snRNA transport
0.51	GO:0006404	RNA import into nucleus
0.51	GO:0034504	protein localization to nucleus
0.50	GO:0033750	ribosome localization
0.49	GO:0071166	ribonucleoprotein complex localization
0.49	GO:0051169	nuclear transport
0.49	GO:0051656	establishment of organelle localization
0.48	GO:0072594	establishment of protein localization to organelle

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.46	GO:0019003	GDP binding
0.45	GO:0070883	pre-miRNA binding
0.44	GO:0045296	cadherin binding
0.43	GO:0000287	magnesium ion binding
0.42	GO:0046982	protein heterodimerization activity
0.38	GO:0061676	importin-alpha family protein binding
0.38	GO:0045505	dynein intermediate chain binding
0.36	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.47	GO:0042565	RNA nuclear export complex
0.45	GO:0030496	midbody
0.45	GO:0055037	recycling endosome
0.45	GO:0005814	centriole
0.42	GO:0000785	chromatin
0.41	GO:0031967	organelle envelope
0.41	GO:0042470	melanosome
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0002177	manchette

sp|P62872|GBB1_CANLF
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Search

GNB1

0.91	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.52	GO:0060041	retina development in camera-type eye
0.51	GO:0050909	sensory perception of taste
0.50	GO:0008283	cell proliferation
0.41	GO:0010659	cardiac muscle cell apoptotic process
0.40	GO:0070208	protein heterotrimerization
0.39	GO:0071456	cellular response to hypoxia
0.39	GO:0048920	posterior lateral line neuromast primordium migration
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071417	cellular response to organonitrogen compound

0.52	GO:0032403	protein complex binding
0.50	GO:0051020	GTPase binding
0.46	GO:0003924	GTPase activity
0.41	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.41	GO:0031702	type 1 angiotensin receptor binding
0.40	GO:0030507	spectrin binding
0.39	GO:0004871	signal transducer activity
0.36	GO:0005246	calcium channel regulator activity

0.55	GO:0043209	myelin sheath
0.52	GO:0001750	photoreceptor outer segment
0.52	GO:1905360	GTPase complex
0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0098797	plasma membrane protein complex
0.41	GO:0060170	ciliary membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0044297	cell body
0.40	GO:0001917	photoreceptor inner segment
0.39	GO:0005765	lysosomal membrane

0.41

GO:0047391

sp|P62999|RAC1_CANLF
Ras-related C3 botulinum toxin substrate 1
Search

RAC1

0.81	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

0.76	GO:0007264	small GTPase mediated signal transduction
0.52	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.52	GO:0032707	negative regulation of interleukin-23 production
0.51	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.51	GO:0010592	positive regulation of lamellipodium assembly
0.51	GO:0060263	regulation of respiratory burst
0.50	GO:0051894	positive regulation of focal adhesion assembly
0.50	GO:0090023	positive regulation of neutrophil chemotaxis
0.50	GO:0097178	ruffle assembly
0.50	GO:0030032	lamellipodium assembly

0.67	GO:0003924	GTPase activity
0.65	GO:0005525	GTP binding
0.51	GO:0031996	thioesterase binding
0.47	GO:0019901	protein kinase binding
0.44	GO:0051022	Rho GDP-dissociation inhibitor binding
0.40	GO:0048306	calcium-dependent protein binding
0.40	GO:0030742	GTP-dependent protein binding
0.39	GO:0051117	ATPase binding
0.39	GO:0042826	histone deacetylase binding
0.38	GO:0017137	Rab GTPase binding

0.50	GO:0005884	actin filament
0.49	GO:0043197	dendritic spine
0.49	GO:0055038	recycling endosome membrane
0.49	GO:0032587	ruffle membrane
0.48	GO:0030027	lamellipodium
0.47	GO:0005802	trans-Golgi network
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0042470	melanosome
0.40	GO:0097732	9+2 non-motile cilium
0.40	GO:0030426	growth cone

0.34

EC:2.3.1.48

GO:0004402

sp|P63050|RL40_CANLF
Ubiquitin-60S ribosomal protein L40
Search

UBA52

0.63	Anopheles stephensi ubiquitin

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.38	GO:0017085	response to insecticide
0.36	GO:0007623	circadian rhythm
0.35	GO:0035635	entry of bacterium into host cell
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0031386	protein tag
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.46	GO:0005829	cytosol
0.43	GO:0005783	endoplasmic reticulum
0.43	GO:0005654	nucleoplasm
0.38	GO:0005886	plasma membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0030666	endocytic vesicle membrane

sp|P63091|GNAS_CANLF
Guanine nucleotide-binding protein G(s) subunit alpha
Search

GNAS

0.79	Guanine nucleotide-binding protein alpha-stimulating activity polypeptide 1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0043950	positive regulation of cAMP-mediated signaling
0.53	GO:0030819	positive regulation of cAMP biosynthetic process
0.53	GO:0019933	cAMP-mediated signaling
0.50	GO:0060789	hair follicle placode formation
0.49	GO:2000828	regulation of parathyroid hormone secretion
0.48	GO:0040032	post-embryonic body morphogenesis
0.48	GO:0043547	positive regulation of GTPase activity
0.48	GO:0070527	platelet aggregation
0.47	GO:0045672	positive regulation of osteoclast differentiation

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.50	GO:0031852	mu-type opioid receptor binding
0.50	GO:0051430	corticotropin-releasing hormone receptor 1 binding
0.50	GO:0031698	beta-2 adrenergic receptor binding
0.50	GO:0031748	D1 dopamine receptor binding
0.49	GO:0035255	ionotropic glutamate receptor binding
0.48	GO:0005159	insulin-like growth factor receptor binding

0.48	GO:1905360	GTPase complex
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0032588	trans-Golgi network membrane
0.45	GO:0030425	dendrite
0.43	GO:0098797	plasma membrane protein complex
0.42	GO:0070062	extracellular exosome
0.42	GO:0005829	cytosol
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0016324	apical plasma membrane
0.39	GO:0042383	sarcolemma

0.44

GO:0047391

sp|P63113|MYG_CANLF
Myoglobin
Search

0.84

Myoglobin

0.79	GO:0015671	oxygen transport
0.46	GO:0043353	enucleate erythrocyte differentiation
0.44	GO:0050873	brown fat cell differentiation
0.44	GO:0001666	response to hypoxia
0.43	GO:0007507	heart development
0.41	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.39	GO:0042542	response to hydrogen peroxide
0.37	GO:0009725	response to hormone

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

sp|P63210|GBG1_CANLF
Guanine nucleotide-binding protein G(T) subunit gamma-T1
Search

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0042462	eye photoreceptor cell development
0.50	GO:0007602	phototransduction
0.44	GO:0008104	protein localization
0.40	GO:0010659	cardiac muscle cell apoptotic process
0.38	GO:0071456	cellular response to hypoxia
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0071482	cellular response to light stimulus
0.35	GO:0009584	detection of visible light

0.64	GO:0004871	signal transducer activity
0.41	GO:0003924	GTPase activity
0.34	GO:0005515	protein binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.81	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.39	GO:0001750	photoreceptor outer segment
0.38	GO:0001917	photoreceptor inner segment
0.37	GO:0060170	ciliary membrane

0.34

EC:1.3.99.3

GO:0003995

sp|P63273|RS17_CANLF
40S ribosomal protein S17
Search

RPS17

0.71	Ribosomal protein S17

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000028	ribosomal small subunit assembly
0.47	GO:0034101	erythrocyte homeostasis
0.42	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0045182	translation regulator activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

sp|P63289|VIP_CANLF
Vasoactive intestinal peptide
Search

VIP

0.92	Vasoactive intestinal peptide

0.76	GO:0010469	regulation of receptor activity
0.73	GO:0070459	prolactin secretion
0.69	GO:0048255	mRNA stabilization
0.56	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.55	GO:0019933	cAMP-mediated signaling
0.50	GO:0032880	regulation of protein localization
0.49	GO:0045732	positive regulation of protein catabolic process
0.46	GO:0007218	neuropeptide signaling pathway
0.43	GO:0007399	nervous system development
0.42	GO:0010562	positive regulation of phosphorus metabolic process

0.79	GO:0005179	hormone activity
0.42	GO:0051428	peptide hormone receptor binding
0.36	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding

0.66	GO:0005576	extracellular region
0.37	GO:0097458	neuron part
0.37	GO:0005622	intracellular
0.36	GO:0120025	plasma membrane bounded cell projection
0.36	GO:0044297	cell body
0.34	GO:0044456	synapse part
0.33	GO:0044463	cell projection part
0.30	GO:0016020	membrane

sp|P67780|COX2_CANLF
Cytochrome c oxidase subunit 2
Search

COX2

0.43	Cytochrome c oxidase subunit 2

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.45	GO:0070069	cytochrome complex
0.42	GO:0098796	membrane protein complex
0.34	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9

GO:0016675

sp|P67811|SC11A_CANLF
Signal peptidase complex catalytic subunit SEC11A
Search

SEC11A

0.72	Signal peptidase complex catalytic subunit SEC11

0.80

GO:0006465

signal peptide processing

0.67

GO:0008236

serine-type peptidase activity

0.82	GO:0005787	signal peptidase complex
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P68004|PYY_CANLF
Peptide YY
Search

PYY

0.64	Peptide YY

0.76	GO:0010469	regulation of receptor activity
0.61	GO:0032098	regulation of appetite
0.61	GO:0007631	feeding behavior
0.59	GO:0007586	digestion
0.58	GO:0007218	neuropeptide signaling pathway
0.54	GO:0007267	cell-cell signaling
0.40	GO:0032096	negative regulation of response to food
0.38	GO:0008283	cell proliferation
0.37	GO:0007010	cytoskeleton organization

0.79	GO:0005179	hormone activity
0.57	GO:0001664	G-protein coupled receptor binding

0.66

GO:0005576

extracellular region

sp|P68213|FIBA_CANLF
Fibrinogen alpha chain (Fragment)
Search

0.51	Fibrinogen alpha chain (Fragment)

0.83	GO:0030168	platelet activation
0.76	GO:0072377	blood coagulation, common pathway
0.76	GO:0051258	protein polymerization
0.74	GO:0043152	induction of bacterial agglutination
0.73	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.72	GO:0042730	fibrinolysis
0.71	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.71	GO:0045907	positive regulation of vasoconstriction
0.71	GO:2000352	negative regulation of endothelial cell apoptotic process
0.71	GO:0031639	plasminogen activation

0.79	GO:0030674	protein binding, bridging
0.71	GO:0005102	receptor binding
0.65	GO:0050839	cell adhesion molecule binding
0.52	GO:0005198	structural molecule activity
0.36	GO:0046872	metal ion binding

0.85	GO:0005577	fibrinogen complex
0.71	GO:0031091	platelet alpha granule
0.66	GO:0009897	external side of plasma membrane
0.62	GO:0005938	cell cortex
0.41	GO:0034774	secretory granule lumen
0.40	GO:0072562	blood microparticle
0.40	GO:0005788	endoplasmic reticulum lumen
0.39	GO:0070062	extracellular exosome

sp|P68280|CRYAA_CANLF
Alpha-crystallin A chain
Search

CRYAA

0.97	Alpha-crystallin A chain

0.53	GO:0070309	lens fiber cell morphogenesis
0.53	GO:0070141	response to UV-A
0.52	GO:0060561	apoptotic process involved in morphogenesis
0.52	GO:0048596	embryonic camera-type eye morphogenesis
0.51	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.50	GO:0007021	tubulin complex assembly
0.50	GO:0042542	response to hydrogen peroxide
0.50	GO:0030307	positive regulation of cell growth
0.50	GO:0001666	response to hypoxia
0.48	GO:0001934	positive regulation of protein phosphorylation

0.85	GO:0005212	structural constituent of eye lens
0.44	GO:0046872	metal ion binding
0.39	GO:0051082	unfolded protein binding
0.35	GO:0042802	identical protein binding

0.47	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.36	GO:0043233	organelle lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part

sp|P79143|AMPN_CANLF
Aminopeptidase N
Search

ANPEP

0.52	Aminopeptidase Ey

0.60	GO:0006508	proteolysis
0.48	GO:0008217	regulation of blood pressure
0.46	GO:0043171	peptide catabolic process
0.45	GO:0007267	cell-cell signaling
0.43	GO:0001525	angiogenesis
0.41	GO:0030154	cell differentiation
0.41	GO:0007165	signal transduction
0.38	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.38	GO:0044409	entry into host
0.37	GO:0019058	viral life cycle

0.70	GO:0004177	aminopeptidase activity
0.66	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.47	GO:0042277	peptide binding
0.42	GO:0104005	hijacked molecular function
0.33	GO:0004872	receptor activity

0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.54	GO:0070062	extracellular exosome
0.53	GO:0009897	external side of plasma membrane
0.41	GO:0005765	lysosomal membrane
0.36	GO:0012506	vesicle membrane
0.35	GO:0031983	vesicle lumen
0.35	GO:0030141	secretory granule
0.34	GO:0044433	cytoplasmic vesicle part
0.30	GO:0016021	integral component of membrane

0.70

EC:3.4.11

GO:0004177

sp|P79144|AQP2_CANLF
Aquaporin-2 (Fragment)
Search

AQP

0.87	ADH water channel (Fragment)

0.57	GO:0071288	cellular response to mercury ion
0.55	GO:0071280	cellular response to copper ion
0.55	GO:0015793	glycerol transport
0.55	GO:0072205	metanephric collecting duct development
0.55	GO:0003097	renal water transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0042631	cellular response to water deprivation
0.38	GO:0006811	ion transport
0.35	GO:0030157	pancreatic juice secretion
0.35	GO:0015670	carbon dioxide transport

0.69	GO:0022803	passive transmembrane transporter activity
0.56	GO:0015168	glycerol transmembrane transporter activity
0.54	GO:0005372	water transmembrane transporter activity
0.35	GO:0005515	protein binding

0.56	GO:0016324	apical plasma membrane
0.51	GO:0055037	recycling endosome
0.51	GO:0070062	extracellular exosome
0.46	GO:0016323	basolateral plasma membrane
0.44	GO:0030659	cytoplasmic vesicle membrane
0.43	GO:0005794	Golgi apparatus
0.40	GO:0005887	integral component of plasma membrane
0.35	GO:0030133	transport vesicle
0.35	GO:0046930	pore complex
0.35	GO:0031303	integral component of endosome membrane

sp|P79145|CREM_CANLF
cAMP-responsive element modulator
Search

CREM

0.92	cAMP-responsive element modulator

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0006687	glycosphingolipid metabolic process
0.44	GO:0007283	spermatogenesis
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0048384	retinoic acid receptor signaling pathway
0.39	GO:0042752	regulation of circadian rhythm
0.38	GO:0048511	rhythmic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0008140	cAMP response element binding protein binding

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P79147|GBB3_CANLF
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Search

GNB3

0.97	GTP-binding protein beta-3 subunit

0.61	GO:0007165	signal transduction
0.46	GO:0060041	retina development in camera-type eye
0.45	GO:0050909	sensory perception of taste
0.45	GO:0008283	cell proliferation
0.38	GO:0010659	cardiac muscle cell apoptotic process
0.38	GO:0070208	protein heterotrimerization
0.37	GO:0071456	cellular response to hypoxia
0.37	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071417	cellular response to organonitrogen compound
0.36	GO:0033762	response to glucagon

0.53	GO:0051020	GTPase binding
0.44	GO:0032403	protein complex binding
0.42	GO:0003924	GTPase activity
0.42	GO:0030507	spectrin binding
0.39	GO:0004871	signal transducer activity
0.38	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.38	GO:0031702	type 1 angiotensin receptor binding
0.36	GO:0005246	calcium channel regulator activity

0.55	GO:0043005	neuron projection
0.54	GO:0120038	plasma membrane bounded cell projection part
0.53	GO:0036477	somatodendritic compartment
0.47	GO:1905360	GTPase complex
0.46	GO:0043209	myelin sheath
0.46	GO:0097731	9+0 non-motile cilium
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0044297	cell body
0.42	GO:0098797	plasma membrane protein complex
0.39	GO:0044422	organelle part

0.38

GO:0047391

sp|P79148|ADRB1_CANLF
Beta-1 adrenergic receptor
Search

0.96	Beta-1 adrenergic receptor

0.84	GO:0071875	adrenergic receptor signaling pathway
0.82	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.72	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.72	GO:0045823	positive regulation of heart contraction
0.69	GO:0001659	temperature homeostasis
0.68	GO:0002024	diet induced thermogenesis
0.67	GO:0040015	negative regulation of multicellular organism growth
0.65	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine
0.64	GO:0043950	positive regulation of cAMP-mediated signaling
0.64	GO:0050873	brown fat cell differentiation

0.85	GO:0004939	beta-adrenergic receptor activity
0.67	GO:0031690	adrenergic receptor binding
0.65	GO:0051380	norepinephrine binding
0.59	GO:0051379	epinephrine binding
0.58	GO:0005057	signal transducer activity, downstream of receptor
0.57	GO:0030165	PDZ domain binding
0.57	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.55	GO:0046983	protein dimerization activity
0.48	GO:0042802	identical protein binding
0.37	GO:0050824	water binding

0.59	GO:0005769	early endosome
0.55	GO:0005886	plasma membrane
0.50	GO:0043235	receptor complex
0.36	GO:0005634	nucleus
0.35	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

0.34

EC:2.6.1

GO:0008483

sp|P79149|PININ_CANLF
Pinin
Search

0.80	Pinin, desmosome associated protein (Fragment)

0.55	GO:0014033	neural crest cell differentiation
0.52	GO:0007155	cell adhesion
0.45	GO:0008380	RNA splicing
0.44	GO:0006397	mRNA processing
0.40	GO:0006351	transcription, DNA-templated
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression

0.45	GO:0003677	DNA binding
0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.73	GO:0035145	exon-exon junction complex
0.70	GO:0071013	catalytic step 2 spliceosome
0.67	GO:0016607	nuclear speck
0.55	GO:0005911	cell-cell junction
0.47	GO:0070161	anchoring junction
0.35	GO:0005882	intermediate filament
0.34	GO:0030424	axon
0.33	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane

sp|P79150|FGF7_CANLF
Fibroblast growth factor 7
Search

FGF7

0.63	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.66	GO:0061033	secretion by lung epithelial cell involved in lung growth
0.65	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.64	GO:0010838	positive regulation of keratinocyte proliferation
0.64	GO:0051549	positive regulation of keratinocyte migration
0.64	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
0.63	GO:0010463	mesenchymal cell proliferation
0.63	GO:0034394	protein localization to cell surface
0.62	GO:0060445	branching involved in salivary gland morphogenesis

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.63	GO:0042056	chemoattractant activity
0.45	GO:0008201	heparin binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0004335	galactokinase activity
0.34	GO:0005534	galactose binding

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P79250|5HT1B_CANLF
5-hydroxytryptamine receptor 1B
Search

HTR1B

0.97	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

0.81	GO:0046849	bone remodeling
0.80	GO:0042310	vasoconstriction
0.80	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.79	GO:0050795	regulation of behavior
0.79	GO:0007631	feeding behavior
0.73	GO:0007268	chemical synaptic transmission
0.63	GO:0014063	negative regulation of serotonin secretion
0.61	GO:0071312	cellular response to alkaloid
0.59	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.59	GO:0071502	cellular response to temperature stimulus

0.80	GO:0099589	serotonin receptor activity
0.77	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.77	GO:0008227	G-protein coupled amine receptor activity
0.58	GO:0051378	serotonin binding
0.41	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.63	GO:0005887	integral component of plasma membrane
0.39	GO:0005737	cytoplasm

sp|P80009|PLMN_CANLF
Plasminogen (Fragment)
Search

0.55	Plasminogen

0.67	GO:0042730	fibrinolysis
0.64	GO:0048771	tissue remodeling
0.63	GO:0007596	blood coagulation
0.61	GO:0006508	proteolysis
0.54	GO:0071674	mononuclear cell migration
0.54	GO:0045445	myoblast differentiation
0.54	GO:0046716	muscle cell cellular homeostasis
0.53	GO:0042246	tissue regeneration
0.51	GO:0060707	trophoblast giant cell differentiation
0.51	GO:0060716	labyrinthine layer blood vessel development

0.69	GO:0004252	serine-type endopeptidase activity
0.50	GO:0019900	kinase binding
0.45	GO:1904854	proteasome core complex binding
0.44	GO:1990405	protein antigen binding
0.44	GO:0034185	apolipoprotein binding
0.41	GO:0051087	chaperone binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0005102	receptor binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0030545	receptor regulator activity

0.53	GO:0005576	extracellular region
0.50	GO:0019897	extrinsic component of plasma membrane
0.42	GO:0009897	external side of plasma membrane
0.38	GO:0044218	other organism cell membrane
0.35	GO:0031982	vesicle
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P80035|LIPG_CANLF
Gastric triacylglycerol lipase
Search

0.49	Gastric triacylglycerol lipase

0.68	GO:0016042	lipid catabolic process
0.49	GO:0048873	homeostasis of number of cells within a tissue
0.48	GO:0048771	tissue remodeling
0.48	GO:0001816	cytokine production
0.47	GO:0030324	lung development
0.46	GO:0006954	inflammatory response
0.46	GO:0008283	cell proliferation
0.45	GO:0000902	cell morphogenesis
0.38	GO:0006108	malate metabolic process
0.35	GO:0070268	cornification

0.59	GO:0016788	hydrolase activity, acting on ester bonds
0.37	GO:0016615	malate dehydrogenase activity
0.34	GO:0008289	lipid binding

0.48	GO:0001650	fibrillar center
0.39	GO:0005576	extracellular region
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.59

EC:3.1

GO:0016788

sp|P81255|IFNA1_CANLF
Interferon alpha-1/2
Search

0.87	Interferon-alpha

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.52	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.52	GO:0002323	natural killer cell activation involved in immune response
0.51	GO:0042100	B cell proliferation
0.50	GO:0002286	T cell activation involved in immune response
0.50	GO:0043330	response to exogenous dsRNA
0.50	GO:0030183	B cell differentiation
0.49	GO:0002250	adaptive immune response
0.49	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.46	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P81455|OSTCN_CANLF
Osteocalcin
Search

BGLAP

0.85	Osteocalcin

0.83	GO:0030500	regulation of bone mineralization
0.63	GO:0031214	biomineral tissue development
0.62	GO:0033280	response to vitamin D
0.60	GO:0001649	osteoblast differentiation
0.41	GO:0033594	response to hydroxyisoflavone
0.40	GO:0032571	response to vitamin K
0.40	GO:0033574	response to testosterone
0.40	GO:0071295	cellular response to vitamin
0.40	GO:0014823	response to activity
0.39	GO:0009629	response to gravity

0.70	GO:0005509	calcium ion binding
0.42	GO:0008147	structural constituent of bone
0.38	GO:0046848	hydroxyapatite binding
0.36	GO:0042803	protein homodimerization activity
0.34	GO:0046914	transition metal ion binding

0.66	GO:0005576	extracellular region
0.43	GO:0005737	cytoplasm
0.39	GO:0043204	perikaryon
0.38	GO:0030425	dendrite
0.37	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part

sp|P81546|TIMP1_CANLF
Metalloproteinase inhibitor 1
Search

TIMP1

0.97	Tissue inhibitor of metalloproteinase 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.73	GO:2001044	regulation of integrin-mediated signaling pathway
0.72	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.69	GO:1901164	negative regulation of trophoblast cell migration
0.68	GO:1905049	negative regulation of metallopeptidase activity
0.65	GO:0008284	positive regulation of cell proliferation
0.62	GO:0010469	regulation of receptor activity
0.51	GO:0034097	response to cytokine
0.50	GO:0009725	response to hormone
0.44	GO:0051216	cartilage development

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.66	GO:0005125	cytokine activity
0.54	GO:0002020	protease binding
0.52	GO:0008083	growth factor activity
0.50	GO:0008270	zinc ion binding
0.35	GO:0008237	metallopeptidase activity

0.66	GO:0005576	extracellular region
0.39	GO:0031093	platelet alpha granule lumen
0.37	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005581	collagen trimer

sp|P81708|LYSC1_CANLF
Lysozyme C, milk isozyme
Search

LYZ

0.50	Lysozyme C, spleen isozyme

0.74	GO:0042742	defense response to bacterium
0.72	GO:0019835	cytolysis
0.45	GO:0016998	cell wall macromolecule catabolic process
0.43	GO:0031640	killing of cells of other organism
0.40	GO:0007586	digestion
0.39	GO:0009566	fertilization
0.35	GO:0045026	plasma membrane fusion
0.35	GO:0005989	lactose biosynthetic process
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism
0.34	GO:0043312	neutrophil degranulation

0.78	GO:0003796	lysozyme activity
0.41	GO:0042802	identical protein binding
0.35	GO:0004461	lactose synthase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0046983	protein dimerization activity

0.47	GO:0005576	extracellular region
0.36	GO:0097223	sperm part
0.36	GO:0030141	secretory granule
0.35	GO:0097729	9+2 motile cilium
0.34	GO:0044437	vacuolar part
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0005766	primary lysosome
0.34	GO:0031983	vesicle lumen
0.33	GO:0012506	vesicle membrane
0.33	GO:0098805	whole membrane

0.78

GO:0003796

sp|P81709|LYSC2_CANLF
Lysozyme C, spleen isozyme
Search

LYZ

0.52	Lysozyme C, spleen isozyme

0.78	GO:0042742	defense response to bacterium
0.77	GO:0019835	cytolysis
0.47	GO:0031640	killing of cells of other organism
0.45	GO:0016998	cell wall macromolecule catabolic process
0.43	GO:0007586	digestion
0.36	GO:0001895	retina homeostasis
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0019730	antimicrobial humoral response
0.34	GO:0006954	inflammatory response
0.32	GO:0044267	cellular protein metabolic process

0.78	GO:0003796	lysozyme activity
0.46	GO:0042802	identical protein binding

0.49	GO:0005576	extracellular region
0.36	GO:0030141	secretory granule
0.35	GO:0048237	rough endoplasmic reticulum lumen
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:0000137	Golgi cis cisterna
0.34	GO:0005902	microvillus
0.34	GO:0030140	trans-Golgi network transport vesicle

0.78

GO:0003796

sp|P81999|DJB11_CANLF
DnaJ homolog subfamily B member 11
Search

DNAJB11

0.94	DnaJ like protein subfamily B member 11

0.69	GO:0006457	protein folding
0.50	GO:0016556	mRNA modification
0.45	GO:0032781	positive regulation of ATPase activity
0.40	GO:0060250	germ-line stem-cell niche homeostasis
0.40	GO:0036098	male germ-line stem cell population maintenance
0.40	GO:0090129	positive regulation of synapse maturation
0.40	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0010951	negative regulation of endopeptidase activity
0.33	GO:0007155	cell adhesion

0.71	GO:0051082	unfolded protein binding
0.39	GO:0005178	integrin binding
0.34	GO:0004869	cysteine-type endopeptidase inhibitor activity

0.43	GO:0005634	nucleus
0.43	GO:0005783	endoplasmic reticulum
0.39	GO:0031594	neuromuscular junction
0.38	GO:0005615	extracellular space
0.37	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.34	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P82008|SEC63_CANLF
Translocation protein SEC63 homolog (Fragments)
Search

0.11	Translocation protein SEC63 homolog (Fragments)

0.83	GO:0031204	posttranslational protein targeting to membrane, translocation
0.60	GO:0001889	liver development
0.53	GO:0010259	multicellular organism aging
0.52	GO:0072001	renal system development
0.51	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.49	GO:0030968	endoplasmic reticulum unfolded protein response
0.49	GO:0042552	myelination
0.37	GO:0006807	nitrogen compound metabolic process

0.35	GO:0003723	RNA binding
0.34	GO:0004872	receptor activity
0.34	GO:0005515	protein binding

0.77	GO:0030176	integral component of endoplasmic reticulum membrane
0.34	GO:0005829	cytosol

sp|P82009|SEC62_CANLF
Translocation protein SEC62 (Fragments)
Search

0.11	Translocation protein SEC62 (Fragments)

0.65	GO:0015031	protein transport
0.49	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.48	GO:0090150	establishment of protein localization to membrane
0.46	GO:0046907	intracellular transport
0.36	GO:0036498	IRE1-mediated unfolded protein response
0.33	GO:0060255	regulation of macromolecule metabolic process

0.34	GO:0004872	receptor activity
0.33	GO:0003677	DNA binding

0.77	GO:0030176	integral component of endoplasmic reticulum membrane
0.42	GO:0005791	rough endoplasmic reticulum
0.34	GO:0005829	cytosol

sp|P82179|TRDN_CANLF
Triadin
Search

TRDN

0.95

Triadin

0.56	GO:0060047	heart contraction
0.55	GO:0051282	regulation of sequestering of calcium ion
0.54	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0086036	regulation of cardiac muscle cell membrane potential
0.54	GO:0010649	regulation of cell communication by electrical coupling
0.53	GO:1901021	positive regulation of calcium ion transmembrane transporter activity
0.52	GO:0050850	positive regulation of calcium-mediated signaling
0.52	GO:2001259	positive regulation of cation channel activity
0.52	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.51	GO:0010522	regulation of calcium ion transport into cytosol

0.71	GO:0005102	receptor binding
0.51	GO:0044325	ion channel binding
0.40	GO:0030674	protein binding, bridging
0.32	GO:0046812	host cell surface binding
0.31	GO:0008270	zinc ion binding
0.31	GO:0003723	RNA binding
0.31	GO:0016301	kinase activity

0.83	GO:0016529	sarcoplasmic reticulum
0.47	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0098588	bounding membrane of organelle
0.45	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.42	GO:0034704	calcium channel complex
0.40	GO:0030314	junctional membrane complex
0.37	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0020008	rhoptry
0.32	GO:0005634	nucleus

sp|P82539|DNJC1_CANLF
DnaJ homolog subfamily C member 1 (Fragment)
Search

0.84	DnaJ homolog subfamily C member 1 (Fragment)

0.65	GO:0050708	regulation of protein secretion
0.59	GO:0006417	regulation of translation
0.57	GO:0006457	protein folding
0.38	GO:0032781	positive regulation of ATPase activity
0.37	GO:0045861	negative regulation of proteolysis

0.62	GO:0051087	chaperone binding
0.55	GO:0003677	DNA binding
0.38	GO:0001671	ATPase activator activity
0.37	GO:0043022	ribosome binding

0.58	GO:0005634	nucleus
0.58	GO:0005783	endoplasmic reticulum
0.48	GO:0005886	plasma membrane
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.38	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.36	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P83286|OPT_CANLF
Opticin
Search

OPTC

0.96	LOW QUALITY PROTEIN: opticin

0.62	GO:0007409	axonogenesis
0.54	GO:0016525	negative regulation of angiogenesis
0.45	GO:0022617	extracellular matrix disassembly
0.40	GO:0007565	female pregnancy

0.49	GO:0005201	extracellular matrix structural constituent
0.40	GO:0005518	collagen binding
0.38	GO:0005539	glycosaminoglycan binding

0.73	GO:0005578	proteinaceous extracellular matrix
0.58	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P83362|SPCS1_CANLF
Signal peptidase complex subunit 1 (Fragments)
Search

0.11	Signal peptidase complex subunit 1 (Fragments)

0.80	GO:0006465	signal peptide processing
0.52	GO:0045047	protein targeting to ER

0.61	GO:0008233	peptidase activity
0.58	GO:0043022	ribosome binding
0.35	GO:0005515	protein binding

0.82	GO:0005787	signal peptidase complex
0.55	GO:0030176	integral component of endoplasmic reticulum membrane
0.42	GO:0031090	organelle membrane

0.61

GO:0008233

sp|P83509|RHG35_CANLF
Rho GTPase-activating protein 35
Search

ARHGAP35

0.96	Rho GTPase-activating protein 35

0.58	GO:0007165	signal transduction
0.56	GO:0043116	negative regulation of vascular permeability
0.56	GO:0045724	positive regulation of cilium assembly
0.56	GO:0090505	epiboly involved in wound healing
0.56	GO:0007413	axonal fasciculation
0.55	GO:0021955	central nervous system neuron axonogenesis
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0035024	negative regulation of Rho protein signal transduction
0.55	GO:0043087	regulation of GTPase activity
0.55	GO:0030950	establishment or maintenance of actin cytoskeleton polarity

0.67	GO:0003924	GTPase activity
0.65	GO:0005525	GTP binding
0.58	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0005096	GTPase activator activity
0.54	GO:0005543	phospholipid binding
0.36	GO:0032794	GTPase activating protein binding
0.36	GO:0003714	transcription corepressor activity
0.35	GO:0032403	protein complex binding

0.53	GO:0036064	ciliary basal body
0.49	GO:0015629	actin cytoskeleton
0.39	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.35	GO:0005886	plasma membrane

sp|P83762|MUCSM_CANLF
Submaxillary mucin (Fragment)
Search

0.86	Submaxillary mucin (Fragment)

0.42	GO:0097264	self proteolysis
0.41	GO:0001522	pseudouridine synthesis
0.39	GO:0006468	protein phosphorylation

0.43	GO:0005201	extracellular matrix structural constituent
0.42	GO:0042302	structural constituent of cuticle
0.41	GO:0009982	pseudouridine synthase activity
0.40	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0003723	RNA binding
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005576	extracellular region
0.42	GO:0005581	collagen trimer
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:5.4.99.12

GO:0009982

sp|P86218|OSTC_CANLF
Oligosaccharyltransferase complex subunit OSTC
Search

OSTC

0.94	Oligosaccharyltransferase complex non-catalytic subunit

0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.36	GO:0006464	cellular protein modification process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.44	GO:0016740	transferase activity
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.53	GO:0008250	oligosaccharyltransferase complex
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016740

sp|P86229|KTAP2_CANLF
Keratinocyte-associated protein 2
Search

KRTCAP2

0.97	LOW QUALITY PROTEIN: keratinocyte-associated protein 2

0.61	GO:0042543	protein N-linked glycosylation via arginine
0.35	GO:0018279	protein N-linked glycosylation via asparagine
0.34	GO:0010951	negative regulation of endopeptidase activity

0.35	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity

0.54	GO:0008250	oligosaccharyltransferase complex
0.34	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.4.1.119

GO:0004579

sp|P92604|NU1M_CANLF
NADH-ubiquinone oxidoreductase chain 1
Search

ND1

0.47	NADH-ubiquinone oxidoreductase chain 1

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0006091	generation of precursor metabolites and energy

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.37	GO:0045271	respiratory chain complex I
0.36	GO:0098798	mitochondrial protein complex
0.35	GO:1990204	oxidoreductase complex
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:1.6.5.3

GO:0008137

sp|P99501|COX5A_CANLF
Cytochrome c oxidase subunit 5A, mitochondrial (Fragment)
Search

0.10	Cytochrome c oxidase subunit 5A, mitochondrial (Fragment)

0.30

GO:0043167

ion binding

0.30	GO:0031975	envelope
0.30	GO:0005737	cytoplasm
0.30	GO:0031090	organelle membrane
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044446	intracellular organelle part

sp|P99502|GRP75_CANLF
Stress-70 protein, mitochondrial (Fragment)
Search

0.10	Stress-70 protein, mitochondrial (Fragment)

0.30	GO:0002683	negative regulation of immune system process
0.30	GO:2000737	negative regulation of stem cell differentiation
0.30	GO:0009987	cellular process
0.30	GO:0048731	system development
0.30	GO:0008152	metabolic process
0.30	GO:0065008	regulation of biological quality
0.30	GO:0051239	regulation of multicellular organismal process
0.30	GO:0071840	cellular component organization or biogenesis
0.30	GO:0002376	immune system process

0.30	GO:0032559	adenyl ribonucleotide binding
0.30	GO:0043167	ion binding
0.30	GO:0008144	drug binding

0.30	GO:0044464	cell part
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0043228	non-membrane-bounded organelle
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0044422	organelle part

sp|P99503|UHA1_CANLF
Unknown protein from spot 11 of 2D-PAGE of heart tissue (Fragment)
Search

sp|P99504|ATPB_CANLF
ATP synthase subunit beta, mitochondrial (Fragment)
Search

0.67	ATP synthase subunit beta, mitochondrial (Fragment)

0.70	GO:0006754	ATP biosynthetic process
0.62	GO:0015992	proton transport

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0016787	hydrolase activity

0.77	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.71	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)

0.51

GO:0016787

sp|P99505|THIO_CANLF
Thioredoxin (Fragment)
Search

0.43	Thioredoxin (Fragment)

0.75	GO:0006662	glycerol ether metabolic process
0.68	GO:0045454	cell redox homeostasis
0.61	GO:0046822	regulation of nucleocytoplasmic transport
0.59	GO:0051223	regulation of protein transport
0.57	GO:0043388	positive regulation of DNA binding
0.55	GO:1900180	regulation of protein localization to nucleus
0.55	GO:0032386	regulation of intracellular transport
0.55	GO:0051457	maintenance of protein location in nucleus
0.53	GO:0055114	oxidation-reduction process
0.52	GO:1904950	negative regulation of establishment of protein localization

0.71	GO:0015035	protein disulfide oxidoreductase activity
0.54	GO:0047134	protein-disulfide reductase activity
0.53	GO:0004791	thioredoxin-disulfide reductase activity
0.52	GO:0015037	peptide disulfide oxidoreductase activity
0.51	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

0.49	GO:0005634	nucleus
0.48	GO:0005576	extracellular region
0.46	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.54	EC:1.8.1.8	GO:0047134
0.53	KEGG:R02016	GO:0004791

sp|P99506|UHA2_CANLF
Unknown protein from spot 6109 of 2D-PAGE of heart tissue (Fragment)
Search

sp|P99507|SUCB1_CANLF
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (Fragment)
Search

0.86	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (Fragment)

0.70	GO:0006099	tricarboxylic acid cycle
0.42	GO:0006104	succinyl-CoA metabolic process
0.40	GO:0006105	succinate metabolic process
0.36	GO:0006780	uroporphyrinogen III biosynthetic process

0.67	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.55	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.58	GO:0005739	mitochondrion
0.50	GO:0043209	myelin sheath
0.37	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.67	EC:6.2.1.5	GO:0004775
0.67	KEGG:R00405	GO:0004775

sp|Q00004|SRP68_CANLF
Signal recognition particle subunit SRP68
Search

SRP68

0.73	Signal recognition particle 68

0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.48	GO:0042493	response to drug

0.84	GO:0030942	endoplasmic reticulum signal peptide binding
0.84	GO:0005047	signal recognition particle binding
0.78	GO:0008312	7S RNA binding
0.51	GO:0019904	protein domain specific binding
0.50	GO:0043022	ribosome binding

0.81	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.53	GO:0005925	focal adhesion
0.48	GO:0005829	cytosol
0.43	GO:0005783	endoplasmic reticulum
0.37	GO:0005730	nucleolus
0.33	GO:0005840	ribosome

tr|Q004B2|Q004B2_CANLF
Carcinoembryonic antigen-related cell adhesion molecule 1 isoform 4L
Search

0.74	Carcinoembryonic antigen-related cell adhesion molecule 1

0.56	GO:0043317	regulation of cytotoxic T cell degranulation
0.55	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.54	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.53	GO:0043301	negative regulation of leukocyte degranulation
0.52	GO:0050860	negative regulation of T cell receptor signaling pathway
0.52	GO:0030334	regulation of cell migration
0.52	GO:0090505	epiboly involved in wound healing
0.51	GO:0016477	cell migration
0.51	GO:0050868	negative regulation of T cell activation
0.50	GO:0042127	regulation of cell proliferation

0.55	GO:0031005	filamin binding
0.53	GO:1990782	protein tyrosine kinase binding
0.53	GO:0019903	protein phosphatase binding
0.51	GO:0042803	protein homodimerization activity
0.49	GO:0003779	actin binding
0.48	GO:0015125	bile acid transmembrane transporter activity
0.45	GO:0005516	calmodulin binding
0.44	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.43	GO:0046790	virion binding
0.43	GO:0035325	Toll-like receptor binding

0.55	GO:0042101	T cell receptor complex
0.51	GO:0009986	cell surface
0.50	GO:0005615	extracellular space
0.50	GO:0005911	cell-cell junction
0.49	GO:0016323	basolateral plasma membrane
0.48	GO:0031528	microvillus membrane
0.47	GO:0045178	basal part of cell
0.47	GO:0016328	lateral plasma membrane
0.47	GO:0031982	vesicle
0.46	GO:0016324	apical plasma membrane

sp|Q00589|SC6A6_CANLF
Sodium- and chloride-dependent taurine transporter
Search

SLC6A6

0.47	Sodium- and chloride-dependent taurine transporter

0.82	GO:0015734	taurine transport
0.76	GO:0006836	neurotransmitter transport
0.54	GO:0055085	transmembrane transport
0.42	GO:0006865	amino acid transport
0.33	GO:0006520	cellular amino acid metabolic process

0.86	GO:0005369	taurine:sodium symporter activity
0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.35	GO:0043210	alkanesulfonate binding
0.34	GO:0015171	amino acid transmembrane transporter activity

0.66

GO:0005887

integral component of plasma membrane

tr|Q005W6|Q005W6_CANLF
BNIP3 (Fragment)
Search

BNIP3

0.66	BCL2 interacting protein 3

0.79	GO:0043065	positive regulation of apoptotic process
0.59	GO:0035694	mitochondrial protein catabolic process
0.58	GO:0097345	mitochondrial outer membrane permeabilization
0.57	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia
0.56	GO:0045837	negative regulation of membrane potential
0.56	GO:0071279	cellular response to cobalt ion
0.55	GO:0016239	positive regulation of macroautophagy
0.55	GO:0010637	negative regulation of mitochondrial fusion
0.55	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.55	GO:0043653	mitochondrial fragmentation involved in apoptotic process

0.51	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.48	GO:0051020	GTPase binding
0.44	GO:0005521	lamin binding
0.33	GO:0019888	protein phosphatase regulator activity

0.62	GO:0005740	mitochondrial envelope
0.53	GO:0031968	organelle outer membrane
0.53	GO:0005635	nuclear envelope
0.51	GO:0014069	postsynaptic density
0.49	GO:0031301	integral component of organelle membrane
0.45	GO:0005783	endoplasmic reticulum
0.42	GO:0016607	nuclear speck
0.38	GO:0030425	dendrite
0.35	GO:0005829	cytosol
0.33	GO:0000159	protein phosphatase type 2A complex

sp|Q00LT9|PRCD_CANLF
Progressive rod-cone degeneration protein
Search

PRCD

0.94	Progressive rod-cone degeneration protein homolog

0.78	GO:0007601	visual perception
0.56	GO:0050896	response to stimulus

0.85	GO:0001750	photoreceptor outer segment
0.71	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.66	GO:0005576	extracellular region

sp|Q00M95|RHDF2_CANLF
Inactive rhomboid protein 2
Search

RHBDF2

0.92	Inactive rhomboid protein 2

0.61	GO:0006508	proteolysis
0.57	GO:0050709	negative regulation of protein secretion
0.50	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.45	GO:0051604	protein maturation
0.37	GO:0015031	protein transport
0.34	GO:0015671	oxygen transport
0.34	GO:0061136	regulation of proteasomal protein catabolic process
0.34	GO:0008283	cell proliferation
0.34	GO:0016477	cell migration

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0019838	growth factor binding
0.34	GO:0005344	oxygen carrier activity
0.34	GO:0019825	oxygen binding
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.51	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0005886	plasma membrane
0.33	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|Q01634|IDUA_CANLF
Alpha-L-iduronidase
Search

IDUA

0.97	Alpha-L-iduronidase

0.62	GO:0030209	dermatan sulfate catabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.37	GO:0007040	lysosome organization
0.37	GO:0035108	limb morphogenesis
0.37	GO:0048705	skeletal system morphogenesis
0.37	GO:0030207	chondroitin sulfate catabolic process
0.36	GO:0000902	cell morphogenesis
0.36	GO:0048878	chemical homeostasis

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.37	GO:0005102	receptor binding

0.41	GO:0005764	lysosome
0.38	GO:0030135	coated vesicle
0.37	GO:0070062	extracellular exosome
0.36	GO:0005775	vacuolar lumen

0.66

EC:3.2.1

GO:0004553

sp|Q01685|TRAM1_CANLF
Translocating chain-associated membrane protein 1
Search

TRAM1

0.88	Translocating chain-associated membrane protein 1

0.56	GO:0015031	protein transport
0.35	GO:0090150	establishment of protein localization to membrane
0.35	GO:0046907	intracellular transport
0.34	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.33	GO:0016032	viral process
0.32	GO:0055085	transmembrane transport

0.33	GO:0004872	receptor activity
0.33	GO:0005515	protein binding

0.44	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|Q01988|UBP11_CANLF
Ubiquitin carboxyl-terminal hydrolase 11 (Fragment)
Search

USP11

0.85	Ubiquitin specific peptidase 11

0.75	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.46	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.45	GO:0030509	BMP signaling pathway
0.45	GO:0007179	transforming growth factor beta receptor signaling pathway
0.42	GO:0016570	histone modification
0.36	GO:0034394	protein localization to cell surface
0.36	GO:0000244	spliceosomal tri-snRNP complex assembly
0.36	GO:0031397	negative regulation of protein ubiquitination
0.35	GO:0031647	regulation of protein stability

0.75	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.47	GO:0061649	ubiquitin modification-dependent histone binding
0.45	GO:0005160	transforming growth factor beta receptor binding
0.45	GO:0046332	SMAD binding
0.44	GO:0004197	cysteine-type endopeptidase activity
0.43	GO:0042802	identical protein binding
0.37	GO:0031685	adenosine receptor binding
0.32	GO:0004672	protein kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding

0.52	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.38	GO:0005694	chromosome
0.34	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.4.19.12

GO:0036459

sp|Q05052|OST48_CANLF
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Search

DDOST

0.78	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

0.85	GO:0018279	protein N-linked glycosylation via asparagine
0.53	GO:0042110	T cell activation
0.51	GO:0034097	response to cytokine
0.38	GO:0006334	nucleosome assembly
0.37	GO:0007018	microtubule-based movement
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070828	heterochromatin organization
0.32	GO:0006355	regulation of transcription, DNA-templated

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0003682	chromatin binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0043234	protein complex
0.41	GO:1990234	transferase complex
0.37	GO:0000786	nucleosome
0.35	GO:0035577	azurophil granule membrane
0.35	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

sp|Q06220|SCF_CANLF
Kit ligand
Search

KITLG

0.97	Kit ligand

0.71	GO:0007155	cell adhesion
0.65	GO:0010469	regulation of receptor activity
0.63	GO:0033026	negative regulation of mast cell apoptotic process
0.63	GO:0070668	positive regulation of mast cell proliferation
0.62	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.62	GO:0045636	positive regulation of melanocyte differentiation
0.61	GO:0035162	embryonic hemopoiesis
0.61	GO:0035234	ectopic germ cell programmed cell death
0.61	GO:0045740	positive regulation of DNA replication
0.60	GO:0008584	male gonad development

0.86	GO:0005173	stem cell factor receptor binding
0.67	GO:0008083	growth factor activity
0.56	GO:0005125	cytokine activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.64	GO:0030175	filopodium
0.62	GO:0030027	lamellipodium
0.52	GO:0005615	extracellular space
0.50	GO:0005886	plasma membrane
0.44	GO:0005856	cytoskeleton
0.42	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|Q075B4|CASPC_CANLF
Caspase-12
Search

0.87	Pro-caspase-12 splice variant

0.68	GO:0042981	regulation of apoptotic process
0.61	GO:0006508	proteolysis
0.57	GO:0012501	programmed cell death
0.55	GO:0050727	regulation of inflammatory response
0.51	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.49	GO:0050718	positive regulation of interleukin-1 beta secretion
0.48	GO:0071310	cellular response to organic substance
0.47	GO:0071260	cellular response to mechanical stimulus
0.47	GO:0034976	response to endoplasmic reticulum stress
0.45	GO:0010243	response to organonitrogen compound

0.75	GO:0004197	cysteine-type endopeptidase activity
0.50	GO:0050700	CARD domain binding
0.42	GO:0019900	kinase binding
0.41	GO:0042802	identical protein binding
0.35	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.35	GO:0002020	protease binding
0.34	GO:0097110	scaffold protein binding

0.61	GO:0097169	AIM2 inflammasome complex
0.61	GO:0072559	NLRP3 inflammasome complex
0.61	GO:0072557	IPAF inflammasome complex
0.52	GO:0072558	NLRP1 inflammasome complex
0.46	GO:0097179	protease inhibitor complex
0.45	GO:0005783	endoplasmic reticulum
0.40	GO:0005739	mitochondrion
0.39	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.75

EC:3.4.22

GO:0004197

sp|Q076A3|MYH13_CANLF
Myosin-13
Search

0.70	Fast myosin heavy chain HCIII

0.74	GO:0007018	microtubule-based movement
0.52	GO:0006936	muscle contraction
0.51	GO:0033275	actin-myosin filament sliding
0.49	GO:0050881	musculoskeletal movement
0.48	GO:0014823	response to activity
0.42	GO:0009267	cellular response to starvation
0.41	GO:0046034	ATP metabolic process
0.37	GO:0001778	plasma membrane repair
0.37	GO:0031034	myosin filament assembly
0.35	GO:0035994	response to muscle stretch

0.77	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0000146	microfilament motor activity
0.43	GO:0005516	calmodulin binding
0.41	GO:0016887	ATPase activity
0.37	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.52	GO:0043292	contractile fiber
0.42	GO:0014704	intercalated disc
0.40	GO:0036464	cytoplasmic ribonucleoprotein granule
0.36	GO:0005826	actomyosin contractile ring
0.35	GO:0005794	Golgi apparatus
0.34	GO:0070062	extracellular exosome
0.34	GO:0005882	intermediate filament
0.33	GO:0005829	cytosol

0.41

GO:0016887

sp|Q076A4|MYH8_CANLF
Myosin-8
Search

0.78	Myosin, heavy polypeptide 8, skeletal muscle, perinatal

0.74	GO:0007018	microtubule-based movement
0.58	GO:0006936	muscle contraction
0.55	GO:0070252	actin-mediated cell contraction
0.53	GO:0014823	response to activity
0.51	GO:0050881	musculoskeletal movement
0.46	GO:0001778	plasma membrane repair
0.42	GO:0046034	ATP metabolic process
0.39	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.77	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0000146	microfilament motor activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005516	calmodulin binding
0.43	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.50	GO:0014704	intercalated disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0005826	actomyosin contractile ring
0.41	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.43

GO:0016887

sp|Q076A5|MYH4_CANLF
Myosin-4
Search

0.76	Myosin, heavy polypeptide 8, skeletal muscle, perinatal

0.74	GO:0007018	microtubule-based movement
0.56	GO:0006936	muscle contraction
0.54	GO:0070252	actin-mediated cell contraction
0.53	GO:0014823	response to activity
0.50	GO:0050881	musculoskeletal movement
0.45	GO:0001778	plasma membrane repair
0.41	GO:0046034	ATP metabolic process
0.38	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0000146	microfilament motor activity
0.46	GO:0005516	calmodulin binding
0.42	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.48	GO:0014704	intercalated disc
0.45	GO:0036464	cytoplasmic ribonucleoprotein granule
0.43	GO:0005826	actomyosin contractile ring
0.40	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.42

GO:0016887

sp|Q076A6|MYH1_CANLF
Myosin-1
Search

0.78	Myosin, heavy polypeptide 1, skeletal muscle, adult

0.74	GO:0007018	microtubule-based movement
0.57	GO:0006936	muscle contraction
0.55	GO:0070252	actin-mediated cell contraction
0.53	GO:0014823	response to activity
0.50	GO:0050881	musculoskeletal movement
0.45	GO:0001778	plasma membrane repair
0.41	GO:0046034	ATP metabolic process
0.38	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005516	calmodulin binding
0.42	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.49	GO:0014704	intercalated disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0005826	actomyosin contractile ring
0.40	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.42

GO:0016887

sp|Q076A7|MYH2_CANLF
Myosin-2
Search

0.77	Myosin, heavy polypeptide 8, skeletal muscle, perinatal

0.74	GO:0007018	microtubule-based movement
0.57	GO:0006936	muscle contraction
0.55	GO:0070252	actin-mediated cell contraction
0.53	GO:0014823	response to activity
0.50	GO:0050881	musculoskeletal movement
0.45	GO:0001778	plasma membrane repair
0.42	GO:0046034	ATP metabolic process
0.38	GO:0031034	myosin filament assembly
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0035994	response to muscle stretch

0.77	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0000146	microfilament motor activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005516	calmodulin binding
0.42	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.59	GO:0043292	contractile fiber
0.49	GO:0014704	intercalated disc
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0005826	actomyosin contractile ring
0.40	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.42

GO:0016887

tr|Q076A8|Q076A8_CANLF
Developmental myosin heavy chain embryonic
Search

0.73	Developmental myosin heavy chain embryonic

0.74	GO:0007018	microtubule-based movement
0.61	GO:0006936	muscle contraction
0.57	GO:0050881	musculoskeletal movement
0.52	GO:0070252	actin-mediated cell contraction
0.49	GO:0014823	response to activity
0.45	GO:0046034	ATP metabolic process
0.43	GO:0001778	plasma membrane repair
0.37	GO:0031034	myosin filament assembly
0.35	GO:0061061	muscle structure development
0.35	GO:0035994	response to muscle stretch

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.60	GO:0000146	microfilament motor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0016887	ATPase activity
0.45	GO:0005516	calmodulin binding
0.39	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.60	GO:0043292	contractile fiber
0.46	GO:0014704	intercalated disc
0.43	GO:0036464	cytoplasmic ribonucleoprotein granule
0.42	GO:0005826	actomyosin contractile ring
0.39	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.45

GO:0016887

sp|Q0Q0E4|GATA4_CANLF
Transcription factor GATA-4
Search

GATA4

0.94	Transcription factor GATA-4

0.68	GO:0045893	positive regulation of transcription, DNA-templated
0.62	GO:0003290	atrial septum secundum morphogenesis
0.61	GO:0060575	intestinal epithelial cell differentiation
0.59	GO:0003197	endocardial cushion development
0.57	GO:0008584	male gonad development
0.55	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0042493	response to drug
0.48	GO:0061026	cardiac muscle tissue regeneration
0.48	GO:0048738	cardiac muscle tissue development
0.47	GO:0003208	cardiac ventricle morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0070410	co-SMAD binding
0.57	GO:0044212	transcription regulatory region DNA binding
0.55	GO:0003713	transcription coactivator activity
0.54	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.53	GO:0008134	transcription factor binding
0.48	GO:0003690	double-stranded DNA binding
0.47	GO:0003682	chromatin binding

0.58	GO:0005634	nucleus
0.54	GO:0005667	transcription factor complex
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.36	GO:0005694	chromosome

0.33

EC:4.2.99.18

GO:0003906

sp|Q0V8T0|CNTP5_CANLF
Contactin-associated protein-like 5
Search

CNTNAP5

0.89	Contactin associated protein like 5

0.44	GO:2000821	regulation of grooming behavior
0.44	GO:0032225	regulation of synaptic transmission, dopaminergic
0.43	GO:0032228	regulation of synaptic transmission, GABAergic
0.38	GO:0007155	cell adhesion

0.44	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding

0.43	GO:0042734	presynaptic membrane
0.41	GO:0030425	dendrite
0.35	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q0X0E5|NB5R3_CANLF
NADH-cytochrome b5 reductase 3
Search

CYB5R3

0.64	NADH-cytochrome b5 reductase

0.52	GO:0055114	oxidation-reduction process
0.42	GO:0006695	cholesterol biosynthetic process
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0008015	blood circulation
0.34	GO:0006805	xenobiotic metabolic process

0.79	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
0.37	GO:0016208	AMP binding
0.37	GO:0043531	ADP binding
0.37	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0051287	NAD binding
0.34	GO:0005515	protein binding

0.50	GO:0005811	lipid droplet
0.47	GO:0005783	endoplasmic reticulum
0.44	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.40	GO:0031968	organelle outer membrane
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0035578	azurophil granule lumen
0.35	GO:0005833	hemoglobin complex

0.79

EC:1.6.2.2

GO:0004128

sp|Q0ZAQ8|PPARD_CANLF
Peroxisome proliferator-activated receptor delta
Search

PPARD

0.96	Peroxisome proliferator-activated receptor delta b

0.79	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0051546	keratinocyte migration
0.59	GO:0043415	positive regulation of skeletal muscle tissue regeneration
0.59	GO:2000288	positive regulation of myoblast proliferation
0.58	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.58	GO:0043616	keratinocyte proliferation
0.58	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.57	GO:0045662	negative regulation of myoblast differentiation
0.57	GO:0006351	transcription, DNA-templated

0.81	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.62	GO:0070539	linoleic acid binding
0.55	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0008134	transcription factor binding
0.51	GO:0046982	protein heterodimerization activity
0.42	GO:0008144	drug binding
0.40	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.50	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen

sp|Q0ZFW8|OOEP_CANLF
Oocyte-expressed protein
Search

OOEP

0.97	Oocyte expressed protein isoform 1

0.59

GO:0003723

RNA binding

0.56

GO:0043234

protein complex

tr|Q1AG03|Q1AG03_CANLF
Calsarcin 2
Search

MYOZ1

0.97	Calsarcin 2

0.63

GO:0030239

myofibril assembly

0.87	GO:0051373	FATZ binding
0.68	GO:0031433	telethonin binding
0.57	GO:0003779	actin binding
0.33	GO:0042302	structural constituent of cuticle
0.32	GO:0003677	DNA binding

0.73	GO:0015629	actin cytoskeleton
0.63	GO:0030018	Z disc
0.50	GO:0031143	pseudopodium
0.41	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q1HE58|RB27A_CANLF
Ras-related protein Rab-27A
Search

RAB27A

0.91	Putative rab subfamily protein of small gtpase

0.62	GO:0045921	positive regulation of exocytosis
0.61	GO:0032400	melanosome localization
0.60	GO:0097278	complement-dependent cytotoxicity
0.60	GO:1903433	regulation of constitutive secretory pathway
0.59	GO:0051904	pigment granule transport
0.58	GO:1990182	exosomal secretion
0.58	GO:0043316	cytotoxic T cell degranulation
0.58	GO:0071985	multivesicular body sorting pathway
0.57	GO:0036257	multivesicular body organization
0.57	GO:0043320	natural killer cell degranulation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.61	GO:0031489	myosin V binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0019904	protein domain specific binding

0.63	GO:0032585	multivesicular body membrane
0.62	GO:0042470	melanosome
0.56	GO:0099503	secretory vesicle
0.56	GO:0030133	transport vesicle
0.54	GO:0001750	photoreceptor outer segment
0.53	GO:0030425	dendrite
0.53	GO:0005764	lysosome
0.52	GO:0005794	Golgi apparatus
0.47	GO:0030136	clathrin-coated vesicle
0.44	GO:0005798	Golgi-associated vesicle

sp|Q1HG70|MP2K2_CANLF
Dual specificity mitogen-activated protein kinase kinase 2
Search

MAP2K2

0.92	Dual specificity mitogen-activated protein kinase kinase 2

0.63	GO:0006468	protein phosphorylation
0.51	GO:0060502	epithelial cell proliferation involved in lung morphogenesis
0.50	GO:0060440	trachea formation
0.49	GO:0030878	thyroid gland development
0.49	GO:0048679	regulation of axon regeneration
0.48	GO:0048538	thymus development
0.48	GO:0060324	face development
0.48	GO:0050772	positive regulation of axonogenesis
0.48	GO:0090170	regulation of Golgi inheritance
0.47	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0004708	MAP kinase kinase activity
0.46	GO:0097110	scaffold protein binding
0.46	GO:0043539	protein serine/threonine kinase activator activity
0.45	GO:0004713	protein tyrosine kinase activity
0.44	GO:0004728	signal transducer, downstream of receptor, with protein tyrosine phosphatase activity

0.44	GO:0005925	focal adhesion
0.43	GO:0005770	late endosome
0.43	GO:0005769	early endosome
0.42	GO:0015630	microtubule cytoskeleton
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0044430	cytoskeletal part
0.41	GO:0005794	Golgi apparatus
0.41	GO:0005829	cytosol
0.41	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0099512	supramolecular fiber

0.70

GO:0004674

sp|Q1HGE8|HSF4_CANLF
Heat shock factor protein 4
Search

HSF4

0.94	Heat shock transcription factor 4

0.62	GO:0070207	protein homotrimerization
0.62	GO:0033169	histone H3-K9 demethylation
0.59	GO:0043010	camera-type eye development
0.57	GO:0008284	positive regulation of cell proliferation
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.57	GO:0045597	positive regulation of cell differentiation
0.56	GO:0007601	visual perception
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0048468	cell development
0.40	GO:0006366	transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.41	GO:0019903	protein phosphatase binding
0.41	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.36	GO:0003714	transcription corepressor activity
0.36	GO:0046983	protein dimerization activity
0.36	GO:0042802	identical protein binding
0.34	GO:0061770	translation elongation factor binding
0.34	GO:0051879	Hsp90 protein binding

0.60	GO:0005634	nucleus
0.52	GO:0070013	intracellular organelle lumen
0.46	GO:0044446	intracellular organelle part
0.34	GO:0005694	chromosome
0.34	GO:0005667	transcription factor complex
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0035770	ribonucleoprotein granule
0.33	GO:0015630	microtubule cytoskeleton
0.33	GO:0005829	cytosol

sp|Q1M199|EPM2A_CANLF
Laforin
Search

EPM2A

0.95	Epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)

0.72	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:0046959	habituation
0.55	GO:0016239	positive regulation of macroautophagy
0.53	GO:0046838	phosphorylated carbohydrate dephosphorylation
0.51	GO:0005977	glycogen metabolic process
0.50	GO:0007399	nervous system development
0.39	GO:0006914	autophagy
0.39	GO:0010923	negative regulation of phosphatase activity
0.38	GO:0032007	negative regulation of TOR signaling
0.36	GO:0016567	protein ubiquitination

0.77	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.72	GO:0004725	protein tyrosine phosphatase activity
0.66	GO:0001871	pattern binding
0.61	GO:0030246	carbohydrate binding
0.52	GO:0019203	carbohydrate phosphatase activity
0.51	GO:0004722	protein serine/threonine phosphatase activity
0.50	GO:0042803	protein homodimerization activity
0.36	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0004386	helicase activity

0.59	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.54	GO:0005844	polysome
0.49	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:3.1.3

GO:0008138

sp|Q1PCT2|APR_CANLF
Phorbol-12-myristate-13-acetate-induced protein 1
Search

PMAIP1

0.97	Phorbol-12-myristate-13-acetate-induced protein 1

0.86	GO:0001836	release of cytochrome c from mitochondria
0.85	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.68	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.68	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.67	GO:0032461	positive regulation of protein oligomerization
0.67	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.66	GO:0010907	positive regulation of glucose metabolic process
0.66	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.66	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.65	GO:0046902	regulation of mitochondrial membrane permeability

0.38

GO:0005515

protein binding

0.54	GO:0005829	cytosol
0.51	GO:0005739	mitochondrion
0.50	GO:0005634	nucleus
0.41	GO:0031968	organelle outer membrane

tr|Q1W2J9|Q1W2J9_CANLF
Major prion protein (Fragment)
Search

PRNP

0.85	Major prion protein (Fragment)

0.78	GO:0051260	protein homooligomerization
0.41	GO:1902938	regulation of intracellular calcium activated chloride channel activity
0.40	GO:0071280	cellular response to copper ion
0.40	GO:1904646	cellular response to amyloid-beta
0.40	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0043525	positive regulation of neuron apoptotic process
0.40	GO:1902951	negative regulation of dendritic spine maintenance
0.40	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade
0.40	GO:0031648	protein destabilization
0.40	GO:1990535	neuron projection maintenance

0.54	GO:0046872	metal ion binding
0.41	GO:0008017	microtubule binding
0.41	GO:0031802	type 5 metabotropic glutamate receptor binding
0.40	GO:0001540	amyloid-beta binding
0.38	GO:0002020	protease binding
0.38	GO:0032403	protein complex binding
0.38	GO:0042802	identical protein binding
0.37	GO:0005539	glycosaminoglycan binding
0.36	GO:0004872	receptor activity
0.35	GO:0004871	signal transducer activity

0.55	GO:0005886	plasma membrane
0.47	GO:0098857	membrane microdomain
0.44	GO:0031225	anchored component of membrane
0.43	GO:0005794	Golgi apparatus
0.40	GO:0106003	amyloid-beta complex
0.39	GO:0016234	inclusion body
0.39	GO:0030425	dendrite
0.38	GO:0031965	nuclear membrane
0.38	GO:0009986	cell surface
0.37	GO:0005829	cytosol

sp|Q1ZZS1|LGSN_CANLF
Lengsin
Search

LGSN

0.97	Lengsin, lens protein with glutamine synthetase domain

0.77	GO:0006542	glutamine biosynthetic process
0.46	GO:0002089	lens morphogenesis in camera-type eye
0.41	GO:0030154	cell differentiation
0.33	GO:0009399	nitrogen fixation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.33	GO:0005515	protein binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005884	actin filament
0.41	GO:0005886	plasma membrane
0.31	GO:0005737	cytoplasm

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|Q20FD0|FGF5_CANLF
Fibroblast growth factor 5
Search

FGF5

0.61	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.74	GO:0010469	regulation of receptor activity
0.61	GO:0023019	signal transduction involved in regulation of gene expression
0.57	GO:0010001	glial cell differentiation
0.56	GO:0008284	positive regulation of cell proliferation
0.45	GO:0061550	cranial ganglion development
0.41	GO:0051781	positive regulation of cell division
0.37	GO:0001502	cartilage condensation
0.37	GO:0045445	myoblast differentiation
0.37	GO:0008283	cell proliferation

0.83	GO:0005104	fibroblast growth factor receptor binding
0.77	GO:0008083	growth factor activity
0.36	GO:0005163	nerve growth factor receptor binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.65	GO:0005576	extracellular region
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|Q258K2|MYH9_CANLF
Myosin-9
Search

MYH9

0.93	Nonmuscle myosin II heavy chain A

0.73	GO:0007018	microtubule-based movement
0.61	GO:1903923	positive regulation of protein processing in phagocytic vesicle
0.60	GO:1903919	negative regulation of actin filament severing
0.58	GO:0032796	uropod organization
0.57	GO:0006911	phagocytosis, engulfment
0.57	GO:0001768	establishment of T cell polarity
0.57	GO:1903131	mononuclear cell differentiation
0.57	GO:0051295	establishment of meiotic spindle localization
0.57	GO:0030220	platelet formation
0.56	GO:0043534	blood vessel endothelial cell migration

0.75	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.56	GO:0000146	microfilament motor activity
0.56	GO:0030898	actin-dependent ATPase activity
0.56	GO:0043495	protein membrane anchor
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0016459	myosin complex
0.57	GO:0001931	uropod
0.56	GO:0001725	stress fiber
0.55	GO:0001772	immunological synapse
0.55	GO:0005925	focal adhesion
0.55	GO:0032154	cleavage furrow
0.55	GO:0005826	actomyosin contractile ring
0.54	GO:0001726	ruffle
0.54	GO:0031594	neuromuscular junction
0.54	GO:0005903	brush border

0.35

GO:0005391

sp|Q28247|CO4A5_CANLF
Collagen alpha-5(IV) chain
Search

COL4A5

0.74	Collagen type IV alpha 5 transcript variant 2

0.60	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.59	GO:0007528	neuromuscular junction development
0.50	GO:0061304	retinal blood vessel morphogenesis
0.48	GO:0001569	branching involved in blood vessel morphogenesis
0.48	GO:0071711	basement membrane organization
0.47	GO:0061333	renal tubule morphogenesis
0.47	GO:0071230	cellular response to amino acid stimulus
0.46	GO:0007420	brain development
0.36	GO:0030855	epithelial cell differentiation
0.35	GO:0030574	collagen catabolic process

0.80	GO:0005201	extracellular matrix structural constituent
0.49	GO:0048407	platelet-derived growth factor binding

0.80	GO:0005604	basement membrane
0.77	GO:0005581	collagen trimer
0.62	GO:0098645	collagen network
0.53	GO:0031594	neuromuscular junction
0.44	GO:0005615	extracellular space
0.34	GO:0005788	endoplasmic reticulum lumen

sp|Q28250|SPCS2_CANLF
Signal peptidase complex subunit 2
Search

SPCS2

0.92	Signal peptidase complex subunit 2

0.80	GO:0006465	signal peptide processing
0.45	GO:0045047	protein targeting to ER
0.35	GO:0032367	intracellular cholesterol transport
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.61	GO:0008233	peptidase activity
0.35	GO:0017127	cholesterol transporter activity
0.34	GO:0004308	exo-alpha-sialidase activity
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005787	signal peptidase complex
0.37	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.61

GO:0008233

sp|Q28256|GP1BA_CANLF
Platelet glycoprotein Ib alpha chain
Search

GP1BA

0.91	Glycoprotein Ib platelet alpha subunit

0.56	GO:0007596	blood coagulation
0.56	GO:0042730	fibrinolysis
0.52	GO:0046426	negative regulation of JAK-STAT cascade
0.52	GO:0007155	cell adhesion
0.50	GO:0006469	negative regulation of protein kinase activity
0.49	GO:0019221	cytokine-mediated signaling pathway
0.45	GO:0000902	cell morphogenesis
0.39	GO:0001775	cell activation
0.39	GO:0006030	chitin metabolic process
0.37	GO:0071526	semaphorin-plexin signaling pathway

0.51	GO:0004860	protein kinase inhibitor activity
0.39	GO:0008061	chitin binding
0.38	GO:0004872	receptor activity
0.37	GO:0004871	signal transducer activity
0.35	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0005515	protein binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0030246	carbohydrate binding
0.34	GO:0003993	acid phosphatase activity
0.34	GO:0050840	extracellular matrix binding

0.56	GO:0031362	anchored component of external side of plasma membrane
0.41	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.37	GO:0005737	cytoplasm
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0097482	muscle cell postsynaptic specialization
0.33	GO:0016328	lateral plasma membrane
0.33	GO:0016607	nuclear speck
0.33	GO:0005884	actin filament
0.33	GO:0005925	focal adhesion

0.35

GO:0004674

sp|Q28259|G3P_CANLF
Glyceraldehyde-3-phosphate dehydrogenase
Search

GAPDH

0.52	Glyceraldehyde-3-phosphate dehydrogenase

0.67	GO:0006006	glucose metabolic process
0.66	GO:0006757	ATP generation from ADP
0.64	GO:0006090	pyruvate metabolic process
0.64	GO:0016052	carbohydrate catabolic process
0.63	GO:0019362	pyridine nucleotide metabolic process
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.48	GO:0051402	neuron apoptotic process
0.46	GO:0051873	killing by host of symbiont cells
0.46	GO:0050821	protein stabilization

0.78	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.65	GO:0050661	NADP binding
0.64	GO:0051287	NAD binding
0.51	GO:0035605	peptidyl-cysteine S-nitrosylase activity
0.47	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.46	GO:0097718	disordered domain specific binding
0.44	GO:0008017	microtubule binding
0.41	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding

0.53	GO:0097452	GAIT complex
0.45	GO:0005829	cytosol
0.44	GO:0005811	lipid droplet
0.43	GO:0031965	nuclear membrane
0.43	GO:0015630	microtubule cytoskeleton
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome

0.78

EC:1.2.1.12

GO:0004365

sp|Q28260|VCAM1_CANLF
Vascular cell adhesion protein 1
Search

0.10	Vascular cell adhesion protein 1

0.77

GO:0098609

cell-cell adhesion

0.30

GO:0031224

intrinsic component of membrane

sp|Q28262|PAFA_CANLF
Platelet-activating factor acetylhydrolase
Search

PLA2G7

0.92	Platelet-activating factor acetylhydrolase

0.69	GO:0016042	lipid catabolic process
0.63	GO:0034441	plasma lipoprotein particle oxidation
0.61	GO:0046469	platelet activating factor metabolic process
0.60	GO:0034374	low-density lipoprotein particle remodeling
0.59	GO:0090026	positive regulation of monocyte chemotaxis
0.54	GO:0034440	lipid oxidation
0.35	GO:0050729	positive regulation of inflammatory response
0.35	GO:0006954	inflammatory response

0.78	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.61	GO:0047499	calcium-independent phospholipase A2 activity
0.52	GO:0005543	phospholipid binding

0.60	GO:0034362	low-density lipoprotein particle
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.78

EC:3.1.1.47

GO:0003847

sp|Q28263|PDE6A_CANLF
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
Search

PDE6A

0.54	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

0.61	GO:0007165	signal transduction
0.60	GO:0007601	visual perception
0.59	GO:0051480	regulation of cytosolic calcium ion concentration
0.55	GO:0046037	GMP metabolic process
0.47	GO:0060041	retina development in camera-type eye
0.45	GO:0009583	detection of light stimulus
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.37	GO:0045494	photoreceptor cell maintenance
0.36	GO:0071482	cellular response to light stimulus
0.35	GO:0198738	cell-cell signaling by wnt

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding

0.48	GO:0001750	photoreceptor outer segment
0.39	GO:0060170	ciliary membrane

0.80

GO:0004114

sp|Q28265|KCMA1_CANLF
Calcium-activated potassium channel subunit alpha-1 (Fragment)
Search

KCNMA1

0.87	Calcium activated potassium channel

0.73	GO:0071805	potassium ion transmembrane transport
0.45	GO:0034465	response to carbon monoxide
0.44	GO:0060083	smooth muscle contraction involved in micturition
0.44	GO:0045794	negative regulation of cell volume
0.42	GO:0030007	cellular potassium ion homeostasis
0.42	GO:0051592	response to calcium ion
0.42	GO:0001666	response to hypoxia
0.41	GO:0042391	regulation of membrane potential
0.41	GO:0006970	response to osmotic stress
0.41	GO:0060082	eye blink reflex

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.77	GO:0005249	voltage-gated potassium channel activity
0.40	GO:0003779	actin binding
0.36	GO:0046872	metal ion binding
0.35	GO:0042802	identical protein binding
0.34	GO:0032403	protein complex binding
0.33	GO:0046983	protein dimerization activity

0.77	GO:0008076	voltage-gated potassium channel complex
0.43	GO:0016324	apical plasma membrane
0.42	GO:0005901	caveola
0.39	GO:0043195	terminal bouton
0.38	GO:0009897	external side of plasma membrane
0.38	GO:0045211	postsynaptic membrane
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0070062	extracellular exosome
0.35	GO:0048787	presynaptic active zone membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

sp|Q28266|KCMB1_CANLF
Calcium-activated potassium channel subunit beta-1
Search

KCNMB1

0.97	Calcium-activated potassium channel beta subunit

0.73	GO:0071805	potassium ion transmembrane transport
0.55	GO:0005513	detection of calcium ion
0.50	GO:0007268	chemical synaptic transmission
0.45	GO:0065009	regulation of molecular function
0.43	GO:1903413	cellular response to bile acid
0.42	GO:0071361	cellular response to ethanol
0.41	GO:0097755	positive regulation of blood vessel diameter
0.41	GO:1901381	positive regulation of potassium ion transmembrane transport
0.41	GO:0071456	cellular response to hypoxia
0.40	GO:0007568	aging

0.84	GO:0015269	calcium-activated potassium channel activity
0.55	GO:0015459	potassium channel regulator activity
0.34	GO:0005515	protein binding

0.50

GO:0008076

voltage-gated potassium channel complex

sp|Q28267|IL12A_CANLF
Interleukin-12 subunit alpha
Search

IL12A

0.97	Interleukin-12 subunit alpha

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.66	GO:0051135	positive regulation of NK T cell activation
0.66	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell
0.66	GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.66	GO:2000510	positive regulation of dendritic cell chemotaxis
0.65	GO:0034393	positive regulation of smooth muscle cell apoptotic process
0.65	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.65	GO:0032700	negative regulation of interleukin-17 production
0.64	GO:0032816	positive regulation of natural killer cell activation

0.87	GO:0005143	interleukin-12 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.71	GO:0042163	interleukin-12 beta subunit binding
0.68	GO:0019975	interleukin-17 binding
0.57	GO:0046982	protein heterodimerization activity

0.73	GO:0005615	extracellular space
0.48	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.37	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|Q28268|IL12B_CANLF
Interleukin-12 subunit beta
Search

IL12B

0.96	Interleukin-12 subunit beta

0.78	GO:0019221	cytokine-mediated signaling pathway
0.74	GO:0010469	regulation of receptor activity
0.64	GO:0010536	positive regulation of activation of Janus kinase activity
0.64	GO:0051140	regulation of NK T cell proliferation
0.64	GO:0032819	positive regulation of natural killer cell proliferation
0.64	GO:0051135	positive regulation of NK T cell activation
0.64	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell
0.64	GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.64	GO:0042104	positive regulation of activated T cell proliferation
0.63	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production

0.80	GO:0004896	cytokine receptor activity
0.79	GO:0005125	cytokine activity
0.67	GO:0042164	interleukin-12 alpha subunit binding
0.65	GO:0045519	interleukin-23 receptor binding
0.56	GO:0008083	growth factor activity
0.55	GO:0046982	protein heterodimerization activity
0.54	GO:0042802	identical protein binding
0.39	GO:0005143	interleukin-12 receptor binding

0.72	GO:0005615	extracellular space
0.46	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q28269|OCLN_CANLF
Occludin
Search

OCLN

0.95	Occludin antigen

0.85	GO:0070830	bicellular tight junction assembly
0.42	GO:0070673	response to interleukin-18
0.41	GO:0071356	cellular response to tumor necrosis factor
0.36	GO:2000810	regulation of bicellular tight junction assembly
0.35	GO:0007605	sensory perception of sound
0.34	GO:0006461	protein complex assembly
0.34	GO:0006414	translational elongation
0.34	GO:0032259	methylation

0.54	GO:0019904	protein domain specific binding
0.36	GO:0008119	thiopurine S-methyltransferase activity
0.34	GO:0003746	translation elongation factor activity

0.79	GO:0005923	bicellular tight junction
0.61	GO:0016327	apicolateral plasma membrane
0.57	GO:0016324	apical plasma membrane
0.57	GO:0030139	endocytic vesicle
0.41	GO:0016328	lateral plasma membrane
0.37	GO:0009986	cell surface
0.36	GO:0061689	tricellular tight junction
0.30	GO:0016021	integral component of membrane

0.36

EC:2.1.1.67

GO:0008119

sp|Q28270|CD34_CANLF
Hematopoietic progenitor cell antigen CD34
Search

CD34

0.97	Hematopoietic progenitor cell antigen CD34

0.72	GO:0007155	cell adhesion
0.71	GO:1900035	negative regulation of cellular response to heat
0.71	GO:0071971	extracellular exosome assembly
0.70	GO:2001214	positive regulation of vasculogenesis
0.69	GO:1901258	positive regulation of macrophage colony-stimulating factor production
0.69	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.69	GO:1900041	negative regulation of interleukin-2 secretion
0.69	GO:0042482	positive regulation of odontogenesis
0.69	GO:0071636	positive regulation of transforming growth factor beta production
0.69	GO:1900038	negative regulation of cellular response to hypoxia

0.64	GO:0043199	sulfate binding
0.56	GO:0030246	carbohydrate binding
0.54	GO:0008134	transcription factor binding
0.34	GO:0003735	structural constituent of ribosome

0.66	GO:0045171	intercellular bridge
0.64	GO:0009897	external side of plasma membrane
0.62	GO:0036053	glomerular endothelium fenestra
0.62	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0009925	basal plasma membrane
0.54	GO:0016324	apical plasma membrane
0.53	GO:0005764	lysosome
0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0005840	ribosome

sp|Q28275|FINC_CANLF
Fibronectin (Fragment)
Search

FN1

0.66	Fibronectin splice variant E (Fragment)

0.60	GO:1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate
0.60	GO:2001202	negative regulation of transforming growth factor-beta secretion
0.59	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction
0.59	GO:0007161	calcium-independent cell-matrix adhesion
0.58	GO:0033622	integrin activation
0.56	GO:0048146	positive regulation of fibroblast proliferation
0.56	GO:0035987	endodermal cell differentiation
0.56	GO:0034446	substrate adhesion-dependent cell spreading
0.56	GO:0051702	interaction with symbiont
0.56	GO:0045773	positive regulation of axon extension

0.56	GO:0097718	disordered domain specific binding
0.55	GO:0005178	integrin binding
0.55	GO:0002020	protease binding
0.55	GO:0008022	protein C-terminus binding
0.54	GO:0016504	peptidase activator activity
0.52	GO:0051087	chaperone binding
0.50	GO:0042802	identical protein binding
0.44	GO:0008201	heparin binding
0.36	GO:0005518	collagen binding
0.36	GO:0045340	mercury ion binding

0.66	GO:0005576	extracellular region
0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.53	GO:0016324	apical plasma membrane
0.49	GO:0031982	vesicle
0.44	GO:0043234	protein complex
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0045178	basal part of cell
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0009986	cell surface
0.34	GO:0099512	supramolecular fiber

sp|Q28278|PROC_CANLF
Vitamin K-dependent protein C
Search

PROC

0.91	Vitamin K-dependent protein C

0.77	GO:0007596	blood coagulation
0.61	GO:1901552	positive regulation of endothelial cell development
0.60	GO:0006508	proteolysis
0.60	GO:1903140	regulation of establishment of endothelial barrier
0.60	GO:0050819	negative regulation of coagulation
0.59	GO:1900047	negative regulation of hemostasis
0.58	GO:0061045	negative regulation of wound healing
0.58	GO:0044537	regulation of circulating fibrinogen levels
0.58	GO:0030193	regulation of blood coagulation
0.57	GO:0050728	negative regulation of inflammatory response

0.69	GO:0004252	serine-type endopeptidase activity
0.67	GO:0005509	calcium ion binding
0.37	GO:0070012	oligopeptidase activity
0.36	GO:0043621	protein self-association
0.35	GO:0016504	peptidase activator activity
0.34	GO:0090729	toxin activity
0.34	GO:0004143	diacylglycerol kinase activity
0.34	GO:0003951	NAD+ kinase activity
0.33	GO:0003677	DNA binding
0.33	GO:0005543	phospholipid binding

0.64	GO:0005576	extracellular region
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005783	endoplasmic reticulum
0.36	GO:1905286	serine-type peptidase complex
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005634	nucleus
0.33	GO:0031982	vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69	EC:3.4.21	GO:0004252
0.34	KEGG:R00104	GO:0003951

sp|Q28279|CNGA1_CANLF
cGMP-gated cation channel alpha-1
Search

CNGA1

0.97	Cyclic nucleotide-gated channel rod photoreceptor subunit alpha

0.73	GO:0007601	visual perception
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0006812	cation transport
0.46	GO:0042391	regulation of membrane potential
0.36	GO:0050896	response to stimulus
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0051480	regulation of cytosolic calcium ion concentration
0.35	GO:0007283	spermatogenesis
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication

0.83	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.51	GO:0005249	voltage-gated potassium channel activity
0.44	GO:0030553	cGMP binding
0.36	GO:0030552	cAMP binding
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.52	GO:0042622	photoreceptor outer segment membrane
0.42	GO:0005887	integral component of plasma membrane
0.37	GO:1902495	transmembrane transporter complex
0.35	GO:0043195	terminal bouton
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|Q28280|A4_CANLF
Amyloid beta A4 protein (Fragment)
Search

APP

0.65	Amyloid-beta A4 protein (Fragment)

0.72	GO:0007399	nervous system development
0.66	GO:0010951	negative regulation of endopeptidase activity
0.54	GO:1905908	positive regulation of amyloid fibril formation
0.54	GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis
0.53	GO:0032640	tumor necrosis factor production
0.53	GO:0150003	regulation of spontaneous synaptic transmission
0.53	GO:1903980	positive regulation of microglial cell activation
0.53	GO:1990535	neuron projection maintenance
0.53	GO:1900272	negative regulation of long-term synaptic potentiation
0.53	GO:0090647	modulation of age-related behavioral decline

0.77	GO:0008201	heparin binding
0.69	GO:0004867	serine-type endopeptidase inhibitor activity
0.55	GO:0046914	transition metal ion binding
0.53	GO:0051425	PTB domain binding
0.46	GO:0042802	identical protein binding
0.46	GO:0005102	receptor binding
0.45	GO:0019899	enzyme binding
0.40	GO:0003677	DNA binding
0.38	GO:0016504	peptidase activator activity
0.36	GO:0097645	amylin binding

0.52	GO:0035253	ciliary rootlet
0.52	GO:0005790	smooth endoplasmic reticulum
0.52	GO:0005641	nuclear envelope lumen
0.51	GO:0043198	dendritic shaft
0.50	GO:0043197	dendritic spine
0.50	GO:0031594	neuromuscular junction
0.50	GO:0051233	spindle midzone
0.50	GO:0030424	axon
0.49	GO:0098589	membrane region
0.49	GO:0045177	apical part of cell

0.34

GO:0008233

sp|Q28281|ARRS_CANLF
S-arrestin
Search

SAG

0.97	S-antigen visual arrestin

0.61	GO:0007165	signal transduction
0.37	GO:0031399	regulation of protein modification process
0.37	GO:0019220	regulation of phosphate metabolic process
0.37	GO:0007601	visual perception
0.36	GO:0006897	endocytosis
0.36	GO:0009416	response to light stimulus
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0071478	cellular response to radiation
0.34	GO:0009582	detection of abiotic stimulus
0.34	GO:0009581	detection of external stimulus

0.60	GO:0002046	opsin binding
0.55	GO:0051219	phosphoprotein binding
0.37	GO:0030507	spectrin binding
0.35	GO:0042802	identical protein binding
0.35	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0004143	diacylglycerol kinase activity
0.34	GO:0003951	NAD+ kinase activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.57	GO:0001750	photoreceptor outer segment
0.57	GO:0001917	photoreceptor inner segment
0.37	GO:0045202	synapse
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.1.107	GO:0004143
0.34	KEGG:R00104	GO:0003951

sp|Q28283|TRIB2_CANLF
Tribbles homolog 2
Search

TRIB2

0.40	Serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0045081	negative regulation of interleukin-10 biosynthetic process
0.59	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0045599	negative regulation of fat cell differentiation
0.50	GO:0050790	regulation of catalytic activity
0.49	GO:0043408	regulation of MAPK cascade
0.45	GO:0045643	regulation of eosinophil differentiation
0.45	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.45	GO:0045659	negative regulation of neutrophil differentiation
0.45	GO:0014912	negative regulation of smooth muscle cell migration

0.64	GO:0004672	protein kinase activity
0.56	GO:0055106	ubiquitin-protein transferase regulator activity
0.54	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0031434	mitogen-activated protein kinase kinase binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008134	transcription factor binding
0.46	GO:0004860	protein kinase inhibitor activity

0.42	GO:0005634	nucleus
0.37	GO:0005856	cytoskeleton
0.36	GO:0005737	cytoplasm

sp|Q28284|CD44_CANLF
CD44 antigen (Fragment)
Search

CD44

0.89	CD44 molecule (Indian blood group)

0.71	GO:0007155	cell adhesion
0.60	GO:2000392	regulation of lamellipodium morphogenesis
0.59	GO:0044319	wound healing, spreading of cells
0.56	GO:1900623	regulation of monocyte aggregation
0.55	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.55	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.55	GO:0030214	hyaluronan catabolic process
0.54	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.53	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.53	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.83	GO:0005540	hyaluronic acid binding
0.51	GO:0004896	cytokine receptor activity
0.38	GO:0005114	type II transforming growth factor beta receptor binding
0.37	GO:0019955	cytokine binding
0.35	GO:0005154	epidermal growth factor receptor binding
0.35	GO:0005518	collagen binding
0.35	GO:0051219	phosphoprotein binding
0.35	GO:0019901	protein kinase binding

0.60	GO:0031258	lamellipodium membrane
0.56	GO:0035692	macrophage migration inhibitory factor receptor complex
0.55	GO:0016324	apical plasma membrane
0.49	GO:0009986	cell surface
0.48	GO:0005902	microvillus
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.41	GO:0016323	basolateral plasma membrane
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome

sp|Q28288|STXB2_CANLF
Syntaxin-binding protein 2
Search

STXBP2

0.90	Syntaxin-binding protein 2

0.80	GO:0006904	vesicle docking involved in exocytosis
0.56	GO:0043312	neutrophil degranulation
0.55	GO:0001909	leukocyte mediated cytotoxicity
0.54	GO:0071346	cellular response to interferon-gamma
0.43	GO:0002576	platelet degranulation
0.42	GO:0070527	platelet aggregation
0.42	GO:0007412	axon target recognition
0.42	GO:1903305	regulation of regulated secretory pathway
0.41	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.41	GO:0016188	synaptic vesicle maturation

0.59	GO:0030348	syntaxin-3 binding
0.56	GO:0017075	syntaxin-1 binding
0.35	GO:0043274	phospholipase binding
0.35	GO:0098772	molecular function regulator
0.34	GO:0047485	protein N-terminus binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0005102	receptor binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0042802	identical protein binding
0.32	GO:0003723	RNA binding

0.57	GO:0044194	cytolytic granule
0.56	GO:0070820	tertiary granule
0.56	GO:0042582	azurophil granule
0.56	GO:0042581	specific granule
0.54	GO:0042589	zymogen granule membrane
0.53	GO:0045335	phagocytic vesicle
0.53	GO:0031201	SNARE complex
0.51	GO:0016324	apical plasma membrane
0.49	GO:0005829	cytosol
0.42	GO:0031091	platelet alpha granule

sp|Q28292|IL1B_CANLF
Interleukin-1 beta
Search

IL1B

0.46	Interleukin-1 beta

0.86	GO:0001660	fever generation
0.84	GO:0051781	positive regulation of cell division
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.59	GO:0035504	regulation of myosin light chain kinase activity
0.58	GO:0070487	monocyte aggregation
0.58	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity
0.57	GO:0030730	sequestering of triglyceride
0.57	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.57	GO:0045086	positive regulation of interleukin-2 biosynthetic process

0.86	GO:0005149	interleukin-1 receptor binding
0.80	GO:0005125	cytokine activity
0.50	GO:0019904	protein domain specific binding

0.83	GO:0005776	autophagosome
0.81	GO:0070062	extracellular exosome
0.78	GO:0005764	lysosome
0.72	GO:0031410	cytoplasmic vesicle
0.68	GO:0005829	cytosol
0.41	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|Q28293|KCNA2_CANLF
Potassium voltage-gated channel subfamily A member 2
Search

KCNA2

0.97	Potassium voltage-gated channel subfamily A member 2

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.58	GO:0021633	optic nerve structural organization
0.57	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep
0.55	GO:0014059	regulation of dopamine secretion
0.46	GO:0019228	neuronal action potential
0.45	GO:0019233	sensory perception of pain
0.42	GO:0071286	cellular response to magnesium ion
0.42	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch

0.78	GO:0005249	voltage-gated potassium channel activity
0.41	GO:0097718	disordered domain specific binding
0.38	GO:0019894	kinesin binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.59	GO:0044224	juxtaparanode region of axon
0.56	GO:0043679	axon terminus
0.56	GO:0032809	neuronal cell body membrane
0.55	GO:0043204	perikaryon
0.54	GO:0030425	dendrite
0.42	GO:0030054	cell junction
0.42	GO:0033270	paranode region of axon
0.41	GO:0042734	presynaptic membrane
0.41	GO:0031258	lamellipodium membrane

sp|Q28294|GNAQ_CANLF
Guanine nucleotide-binding protein G(q) subunit alpha
Search

GNAQ

0.79	Guanine nucleotide binding protein q polypeptide

0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0007603	phototransduction, visible light
0.52	GO:0009649	entrainment of circadian clock
0.51	GO:1905145	cellular response to acetylcholine
0.51	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.47	GO:0001508	action potential
0.47	GO:0045634	regulation of melanocyte differentiation
0.46	GO:0042711	maternal behavior
0.46	GO:0019933	cAMP-mediated signaling
0.46	GO:0021884	forebrain neuron development

0.78	GO:0031683	G-protein beta/gamma-subunit complex binding
0.77	GO:0001664	G-protein coupled receptor binding
0.65	GO:0003924	GTPase activity
0.63	GO:0005525	GTP binding
0.62	GO:0004871	signal transducer activity
0.43	GO:0005096	GTPase activator activity
0.38	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.36	GO:0046872	metal ion binding

0.52	GO:0001750	photoreceptor outer segment
0.44	GO:1905360	GTPase complex
0.44	GO:0030425	dendrite
0.44	GO:0044297	cell body
0.43	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0031965	nuclear membrane
0.40	GO:0098797	plasma membrane protein complex
0.37	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005901	caveola

0.38

GO:0047391

sp|Q28295|VWF_CANLF
von Willebrand factor
Search

0.10	von Willebrand factor

0.56	GO:0030168	platelet activation
0.55	GO:0031589	cell-substrate adhesion
0.53	GO:0051260	protein homooligomerization
0.36	GO:0007597	blood coagulation, intrinsic pathway
0.36	GO:0002576	platelet degranulation
0.36	GO:0001890	placenta development
0.36	GO:0001889	liver development
0.35	GO:0030198	extracellular matrix organization

0.58	GO:0019865	immunoglobulin binding
0.57	GO:0047485	protein N-terminus binding
0.56	GO:0005178	integrin binding
0.56	GO:0002020	protease binding
0.55	GO:0005518	collagen binding
0.53	GO:0051087	chaperone binding
0.52	GO:0042803	protein homodimerization activity

0.66	GO:0005576	extracellular region
0.60	GO:0033093	Weibel-Palade body
0.49	GO:0005783	endoplasmic reticulum
0.36	GO:0031093	platelet alpha granule lumen
0.36	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q28296|MAL_CANLF
Myelin and lymphocyte protein
Search

MAL

0.96	myelin and lymphocyte protein isoform X1

0.57	GO:0001766	membrane raft polarization
0.54	GO:0045056	transcytosis
0.53	GO:0042552	myelination
0.51	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.45	GO:0008104	protein localization
0.35	GO:0007417	central nervous system development
0.35	GO:0006915	apoptotic process
0.34	GO:0030154	cell differentiation
0.34	GO:0046907	intracellular transport
0.34	GO:0070727	cellular macromolecule localization

0.64	GO:0019911	structural constituent of myelin sheath
0.36	GO:0016505	peptidase activator activity involved in apoptotic process
0.34	GO:0008289	lipid binding
0.34	GO:0005515	protein binding

0.64	GO:0045121	membrane raft
0.48	GO:0005783	endoplasmic reticulum
0.40	GO:0016324	apical plasma membrane
0.36	GO:0019898	extrinsic component of membrane
0.34	GO:0000139	Golgi membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q28298|RRBP1_CANLF
Ribosome-binding protein 1
Search

RRBP1

0.84	Ribosome-binding protein 1

0.63	GO:0015031	protein transport
0.54	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation
0.41	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process
0.37	GO:0001649	osteoblast differentiation
0.35	GO:0007165	signal transduction

0.42	GO:0004872	receptor activity
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.75	GO:0030176	integral component of endoplasmic reticulum membrane
0.50	GO:0030141	secretory granule
0.50	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005615	extracellular space
0.41	GO:0005840	ribosome

sp|Q28300|GNAT1_CANLF
Guanine nucleotide-binding protein G(t) subunit alpha-1
Search

GNAT1

0.79	Short photoreceptor transducin-alpha subunit

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.62	GO:0050917	sensory perception of umami taste
0.58	GO:0050908	detection of light stimulus involved in visual perception
0.56	GO:0042462	eye photoreceptor cell development
0.55	GO:0071257	cellular response to electrical stimulus
0.55	GO:0060041	retina development in camera-type eye
0.55	GO:0007603	phototransduction, visible light
0.51	GO:0050913	sensory perception of bitter taste
0.50	GO:0008283	cell proliferation
0.48	GO:0050916	sensory perception of sweet taste

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0001664	G-protein coupled receptor binding
0.37	GO:0000035	acyl binding
0.36	GO:0019901	protein kinase binding

0.60	GO:0001917	photoreceptor inner segment
0.58	GO:0001750	photoreceptor outer segment
0.53	GO:0032391	photoreceptor connecting cilium
0.49	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0098797	plasma membrane protein complex
0.41	GO:0016324	apical plasma membrane
0.38	GO:0030141	secretory granule
0.38	GO:0043025	neuronal cell body
0.38	GO:0097223	sperm part

sp|Q28309|AA3R_CANLF
Adenosine receptor A3
Search

ADORA3

0.74	Adenosine receptor A3

0.85	GO:0001973	adenosine receptor signaling pathway
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0030336	negative regulation of cell migration
0.50	GO:0008285	negative regulation of cell proliferation
0.39	GO:0002441	histamine secretion involved in inflammatory response
0.38	GO:0043306	positive regulation of mast cell degranulation
0.38	GO:0070257	positive regulation of mucus secretion
0.38	GO:0043303	mast cell degranulation
0.38	GO:0050850	positive regulation of calcium-mediated signaling
0.38	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.33	GO:0042803	protein homodimerization activity

0.55	GO:0005886	plasma membrane
0.38	GO:0042629	mast cell granule
0.35	GO:0098793	presynapse
0.30	GO:0016021	integral component of membrane

sp|Q28343|PGCA_CANLF
Aggrecan core protein
Search

ACAN

0.91

Aggrecan

0.72	GO:0007155	cell adhesion
0.64	GO:0001502	cartilage condensation
0.64	GO:0002063	chondrocyte development
0.63	GO:0030199	collagen fibril organization
0.62	GO:0030166	proteoglycan biosynthetic process
0.59	GO:0007507	heart development
0.50	GO:0007417	central nervous system development
0.38	GO:0060591	chondroblast differentiation
0.37	GO:0009629	response to gravity
0.37	GO:0010447	response to acidic pH

0.84	GO:0005540	hyaluronic acid binding
0.60	GO:0005509	calcium ion binding
0.51	GO:0005201	extracellular matrix structural constituent
0.42	GO:0030246	carbohydrate binding
0.37	GO:0005515	protein binding

0.60	GO:0005604	basement membrane
0.55	GO:0005615	extracellular space
0.38	GO:0072534	perineuronal net
0.37	GO:0043025	neuronal cell body
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen
0.36	GO:0043005	neuron projection
0.30	GO:0016020	membrane

sp|Q28346|RL4_CANLF
60S ribosomal protein L4
Search

RPL4

0.70	Ribosomal protein L4

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0003360	brainstem development
0.35	GO:0045773	positive regulation of axon extension
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0071417	cellular response to organonitrogen compound
0.34	GO:0007420	brain development
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.48	GO:0005791	rough endoplasmic reticulum
0.43	GO:0044445	cytosolic part
0.41	GO:0005634	nucleus
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031672	A band
0.35	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q28350|MYC_CANLF
Myc proto-oncogene protein
Search

MYC

0.92	MYC proto-oncogene, bHLH transcription factor

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0045656	negative regulation of monocyte differentiation
0.56	GO:0010468	regulation of gene expression
0.56	GO:0048146	positive regulation of fibroblast proliferation
0.54	GO:0010332	response to gamma radiation
0.54	GO:0060070	canonical Wnt signaling pathway
0.54	GO:2001022	positive regulation of response to DNA damage stimulus
0.53	GO:0032204	regulation of telomere maintenance
0.53	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0046983	protein dimerization activity
0.55	GO:0070888	E-box binding
0.49	GO:0032403	protein complex binding
0.39	GO:0070491	repressing transcription factor binding
0.38	GO:0033613	activating transcription factor binding
0.38	GO:0071074	eukaryotic initiation factor eIF2 binding
0.36	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0003729	mRNA binding

0.61	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005791	rough endoplasmic reticulum
0.36	GO:0042025	host cell nucleus
0.36	GO:0030424	axon
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005739	mitochondrion
0.35	GO:0043234	protein complex

tr|Q28874|Q28874_CANLF
Tissue factor pathway inhibitor
Search

0.43	Tissue factor pathway inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.72	GO:0050878	regulation of body fluid levels
0.71	GO:0050817	coagulation
0.69	GO:0042060	wound healing
0.62	GO:0050819	negative regulation of coagulation
0.62	GO:0061045	negative regulation of wound healing
0.58	GO:0071383	cellular response to steroid hormone stimulus
0.37	GO:0007166	cell surface receptor signaling pathway
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0032355	response to estradiol

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0004948	calcitonin receptor activity
0.34	GO:0008233	peptidase activity
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0005576	extracellular region
0.61	GO:0005901	caveola
0.56	GO:0009986	cell surface
0.36	GO:0031225	anchored component of membrane
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0008233

sp|Q28894|WFDC2_CANLF
WAP four-disulfide core domain protein 2
Search

WFDC2

0.94	WAP four-disulfide core domain protein 2

0.76	GO:0010466	negative regulation of peptidase activity
0.63	GO:0052548	regulation of endopeptidase activity
0.42	GO:0006508	proteolysis
0.37	GO:0007283	spermatogenesis
0.36	GO:0006030	chitin metabolic process
0.35	GO:0007229	integrin-mediated signaling pathway

0.76	GO:0030414	peptidase inhibitor activity
0.64	GO:0061135	endopeptidase regulator activity
0.41	GO:0008233	peptidase activity
0.36	GO:0008061	chitin binding

0.66	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.30	GO:0016020	membrane

0.41

GO:0008233

sp|Q28895|NPC2_CANLF
Epididymal secretory protein E1
Search

NPC2

0.89	NPC intracellular cholesterol transporter 2

0.85	GO:0032367	intracellular cholesterol transport
0.76	GO:0033344	cholesterol efflux
0.74	GO:0042632	cholesterol homeostasis
0.67	GO:0009615	response to virus

0.76	GO:0017127	cholesterol transporter activity
0.73	GO:0015485	cholesterol binding
0.63	GO:0019899	enzyme binding

0.69	GO:0005764	lysosome
0.64	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle

sp|Q28896|CD52_CANLF
CAMPATH-1 antigen
Search

CD52

0.97	CAMPATH-1 antigen

0.63	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.47	GO:0045730	respiratory burst
0.47	GO:0006501	C-terminal protein lipidation

0.62	GO:0031225	anchored component of membrane
0.46	GO:0005886	plasma membrane
0.44	GO:0097225	sperm midpiece
0.41	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q28923|YES_CANLF
Tyrosine-protein kinase Yes
Search

YES1

0.58	Tyrosine-protein kinase Yes

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.50	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.50	GO:0046777	protein autophosphorylation
0.49	GO:0071300	cellular response to retinoic acid
0.48	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.48	GO:0071560	cellular response to transforming growth factor beta stimulus
0.47	GO:0015758	glucose transport
0.46	GO:0045087	innate immune response
0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.46	GO:0016477	cell migration

0.81	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0001784	phosphotyrosine residue binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0044325	ion channel binding
0.47	GO:0019899	enzyme binding
0.44	GO:0005102	receptor binding
0.33	GO:0032403	protein complex binding

0.48	GO:0005884	actin filament
0.47	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0005815	microtubule organizing center
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0016235	aggresome
0.34	GO:0032587	ruffle membrane
0.30	GO:0016021	integral component of membrane

0.81

EC:2.7.10.2

GO:0004715

sp|Q29393|PGS2_CANLF
Decorin
Search

DCN

0.97

Decorin

0.61	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.60	GO:0051901	positive regulation of mitochondrial depolarization
0.60	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.59	GO:0090141	positive regulation of mitochondrial fission
0.58	GO:0010596	negative regulation of endothelial cell migration
0.58	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.57	GO:0016239	positive regulation of macroautophagy
0.56	GO:0016525	negative regulation of angiogenesis
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0046426	negative regulation of JAK-STAT cascade

0.83	GO:0005518	collagen binding
0.56	GO:0050840	extracellular matrix binding
0.52	GO:0005539	glycosaminoglycan binding
0.48	GO:0004860	protein kinase inhibitor activity
0.40	GO:0047485	protein N-terminus binding
0.36	GO:0098633	collagen fibril binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0003723	RNA binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0005615	extracellular space
0.43	GO:0098647	collagen beaded filament
0.39	GO:0005581	collagen trimer
0.36	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|Q29416|IL2_CANLF
Interleukin-2
Search

IL2

0.96	Interleukin-2

0.83	GO:0002250	adaptive immune response
0.76	GO:0010469	regulation of receptor activity
0.61	GO:0046013	regulation of T cell homeostatic proliferation
0.60	GO:0002903	negative regulation of B cell apoptotic process
0.60	GO:0042104	positive regulation of activated T cell proliferation
0.60	GO:0032740	positive regulation of interleukin-17 production
0.60	GO:0051024	positive regulation of immunoglobulin secretion
0.60	GO:2000320	negative regulation of T-helper 17 cell differentiation
0.59	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.59	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein

0.87	GO:0005134	interleukin-2 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.41	GO:0031851	kappa-type opioid receptor binding
0.40	GO:0043208	glycosphingolipid binding
0.37	GO:0019209	kinase activator activity
0.36	GO:0030246	carbohydrate binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.73	GO:0005615	extracellular space
0.32	GO:0005622	intracellular

sp|Q29467|I5P1_CANLF
Type I inositol 1,4,5-trisphosphate 5-phosphatase
Search

INPP5A

0.92	Inositol polyphosphate-5-phosphatase A

0.80	GO:0046856	phosphatidylinositol dephosphorylation
0.49	GO:0046855	inositol phosphate dephosphorylation
0.49	GO:0048016	inositol phosphate-mediated signaling

0.57	GO:0042731	PH domain binding
0.54	GO:0004445	inositol-polyphosphate 5-phosphatase activity
0.38	GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
0.38	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity

0.37	GO:0070062	extracellular exosome
0.35	GO:0005622	intracellular
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.54	EC:3.1.3.56	GO:0004445
0.38	KEGG:R03430	GO:0052659

sp|Q29471|ANX13_CANLF
Annexin A13
Search

ANXA13

0.57

Annexin

0.39	GO:0042997	negative regulation of Golgi to plasma membrane protein transport
0.38	GO:0042998	positive regulation of Golgi to plasma membrane protein transport
0.38	GO:0043652	engulfment of apoptotic cell
0.36	GO:0043086	negative regulation of catalytic activity
0.34	GO:0030154	cell differentiation
0.34	GO:0050819	negative regulation of coagulation
0.33	GO:0007017	microtubule-based process
0.33	GO:0007010	cytoskeleton organization
0.33	GO:2000145	regulation of cell motility

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.42	GO:0001786	phosphatidylserine binding
0.40	GO:1901611	phosphatidylglycerol binding
0.38	GO:0031210	phosphatidylcholine binding
0.38	GO:0004859	phospholipase inhibitor activity
0.38	GO:0008429	phosphatidylethanolamine binding
0.37	GO:0005545	1-phosphatidylinositol binding
0.37	GO:0008201	heparin binding
0.35	GO:0005198	structural molecule activity

0.50	GO:0005654	nucleoplasm
0.44	GO:0005886	plasma membrane
0.37	GO:0070382	exocytic vesicle
0.37	GO:0045121	membrane raft
0.37	GO:0045177	apical part of cell
0.37	GO:0070062	extracellular exosome
0.37	GO:0005882	intermediate filament
0.33	GO:0005874	microtubule

sp|Q29473|CP2DF_CANLF
Cytochrome P450 2D15
Search

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0019369	arachidonic acid metabolic process
0.37	GO:0090349	negative regulation of cellular organohalogen metabolic process
0.37	GO:0090348	regulation of cellular organofluorine metabolic process
0.37	GO:0009822	alkaloid catabolic process
0.37	GO:0033076	isoquinoline alkaloid metabolic process
0.37	GO:0009804	coumarin metabolic process
0.37	GO:0006587	serotonin biosynthetic process from tryptophan
0.37	GO:0016098	monoterpenoid metabolic process
0.36	GO:0042416	dopamine biosynthetic process

0.80	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.47	GO:0008395	steroid hydroxylase activity
0.36	GO:0008391	arachidonic acid monooxygenase activity
0.34	GO:0019825	oxygen binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0016712

sp|Q29476|ST1A1_CANLF
Sulfotransferase 1A1
Search

0.56	Sulfotransferase

0.50	GO:0051923	sulfation
0.46	GO:0018958	phenol-containing compound metabolic process
0.46	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.45	GO:0006068	ethanol catabolic process
0.44	GO:0006805	xenobiotic metabolic process
0.42	GO:0008202	steroid metabolic process
0.42	GO:0042445	hormone metabolic process
0.42	GO:0009812	flavonoid metabolic process
0.39	GO:0000103	sulfate assimilation
0.39	GO:0006575	cellular modified amino acid metabolic process

0.77	GO:0008146	sulfotransferase activity
0.35	GO:0005515	protein binding
0.35	GO:0043199	sulfate binding
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding

0.37

GO:0005829

cytosol

0.77

EC:2.8.2

GO:0008146

sp|Q29536|KPYR_CANLF
Pyruvate kinase PKLR
Search

PKLR

0.47	Pyruvate kinase PKLR

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.47	GO:0032869	cellular response to insulin stimulus
0.40	GO:0012501	programmed cell death
0.39	GO:0071872	cellular response to epinephrine stimulus
0.39	GO:0010226	response to lithium ion
0.38	GO:0051591	response to cAMP
0.38	GO:0033198	response to ATP

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.41	GO:0045296	cadherin binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005248	voltage-gated sodium channel activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.41	GO:0043209	myelin sheath
0.41	GO:0005829	cytosol
0.40	GO:0005929	cilium
0.37	GO:0005634	nucleus
0.36	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.78

EC:2.7.1.40

GO:0004743

sp|Q29537|P53_CANLF
Cellular tumor antigen p53
Search

TP53

0.84	Cellular tumor antigen p53

0.78	GO:0006915	apoptotic process
0.75	GO:0051262	protein tetramerization
0.67	GO:0007049	cell cycle
0.61	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.61	GO:0000733	DNA strand renaturation
0.59	GO:0030308	negative regulation of cell growth
0.58	GO:0007569	cell aging
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.57	GO:0072717	cellular response to actinomycin D

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001084	transcription factor activity, TFIID-class binding
0.55	GO:0001094	TFIID-class transcription factor binding
0.55	GO:0002039	p53 binding
0.55	GO:0035035	histone acetyltransferase binding
0.54	GO:0051721	protein phosphatase 2A binding
0.54	GO:0097718	disordered domain specific binding
0.54	GO:1990837	sequence-specific double-stranded DNA binding
0.54	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.51	GO:0005667	transcription factor complex
0.49	GO:0000785	chromatin
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0005737	cytoplasm
0.45	GO:0012505	endomembrane system
0.42	GO:0005657	replication fork
0.36	GO:0035861	site of double-strand break
0.33	GO:0005886	plasma membrane

sp|Q29611|CLN3_CANLF
Battenin
Search

CLN3

0.88

Battenin

0.60	GO:0007040	lysosome organization
0.57	GO:0097352	autophagosome maturation
0.57	GO:0043524	negative regulation of neuron apoptotic process
0.56	GO:0050885	neuromuscular process controlling balance
0.56	GO:0051489	regulation of filopodium assembly
0.56	GO:0008306	associative learning
0.56	GO:0001508	action potential
0.54	GO:0072659	protein localization to plasma membrane
0.54	GO:0051480	regulation of cytosolic calcium ion concentration
0.52	GO:0035235	ionotropic glutamate receptor signaling pathway

0.56	GO:0048306	calcium-dependent protein binding
0.34	GO:0051082	unfolded protein binding

0.81	GO:0005765	lysosomal membrane
0.55	GO:0005769	early endosome
0.55	GO:0005776	autophagosome
0.55	GO:0005770	late endosome
0.43	GO:0005901	caveola
0.43	GO:0008021	synaptic vesicle
0.42	GO:0005802	trans-Golgi network
0.42	GO:0030176	integral component of endoplasmic reticulum membrane
0.42	GO:0043005	neuron projection
0.41	GO:0005795	Golgi stack

tr|Q2A652|Q2A652_CANLF
G-protein coupled receptor
Search

PTGDR2

0.59	G-protein coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:2000255	negative regulation of male germ cell proliferation
0.59	GO:0019722	calcium-mediated signaling
0.59	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.53	GO:0006935	chemotaxis
0.48	GO:0007268	chemical synaptic transmission
0.46	GO:0002430	complement receptor mediated signaling pathway
0.44	GO:1904646	cellular response to amyloid-beta
0.44	GO:0050900	leukocyte migration
0.44	GO:0090026	positive regulation of monocyte chemotaxis

0.72	GO:0004930	G-protein coupled receptor activity
0.56	GO:0001653	peptide receptor activity
0.52	GO:0042923	neuropeptide binding
0.46	GO:0004875	complement receptor activity
0.45	GO:0005124	scavenger receptor binding
0.36	GO:0050786	RAGE receptor binding
0.35	GO:0038024	cargo receptor activity

0.48	GO:0043005	neuron projection
0.47	GO:0005887	integral component of plasma membrane
0.38	GO:0005622	intracellular
0.33	GO:0012506	vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system

tr|Q2ABC6|Q2ABC6_CANLF
Taste receptor type 2
Search

0.67	Taste receptor type 2 member 7

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0050907	detection of chemical stimulus involved in sensory perception
0.34	GO:0032467	positive regulation of cytokinesis

0.72	GO:0004930	G-protein coupled receptor activity
0.65	GO:0033038	bitter taste receptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q2ABC7|Q2ABC7_CANLF
Taste receptor type 2
Search

0.67	Taste receptor type 2 member 7

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0050907	detection of chemical stimulus involved in sensory perception
0.41	GO:0032467	positive regulation of cytokinesis

0.72	GO:0004930	G-protein coupled receptor activity
0.63	GO:0033038	bitter taste receptor activity

0.35	GO:0060170	ciliary membrane
0.33	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

tr|Q2ABC8|Q2ABC8_CANLF
Taste receptor type 2
Search

0.67	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0050907	detection of chemical stimulus involved in sensory perception
0.34	GO:0032467	positive regulation of cytokinesis

0.72	GO:0004930	G-protein coupled receptor activity
0.53	GO:0033038	bitter taste receptor activity

0.40	GO:0060170	ciliary membrane
0.36	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

tr|Q2ABC9|Q2ABC9_CANLF
Taste receptor type 2
Search

0.65	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0050907	detection of chemical stimulus involved in sensory perception
0.35	GO:0007585	respiratory gaseous exchange

0.72	GO:0004930	G-protein coupled receptor activity
0.53	GO:0033038	bitter taste receptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q2ABD0|Q2ABD0_CANLF
Taste receptor type 2
Search

0.68	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.67	GO:0033038	bitter taste receptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q2ABD3|Q2ABD3_CANLF
Taste receptor type 2
Search

0.66	Taste receptor type 2 member 8

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.59	GO:0033038	bitter taste receptor activity

0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q2ABD4|Q2ABD4_CANLF
Taste receptor type 2
Search

0.67	Taste receptor type 2 member 7

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.69	GO:0033038	bitter taste receptor activity

0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q2ABD5|Q2ABD5_CANLF
Taste receptor type 2
Search

0.67	Taste receptor type 2 member 7

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0050907	detection of chemical stimulus involved in sensory perception

0.79	GO:0033038	bitter taste receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q2ABD6|Q2ABD6_CANLF
Taste receptor type 2
Search

TAS2R5

0.60	Taste receptor type 2 member 5

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0050907	detection of chemical stimulus involved in sensory perception
0.38	GO:0007635	chemosensory behavior
0.35	GO:0006260	DNA replication

0.72	GO:0004930	G-protein coupled receptor activity
0.59	GO:0033038	bitter taste receptor activity
0.36	GO:0003697	single-stranded DNA binding

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q2ABD8|Q2ABD8_CANLF
Taste receptor type 2
Search

TAS2R3

0.67	Taste receptor type 2 member 3

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.60	GO:0033038	bitter taste receptor activity

0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q2ABD9|Q2ABD9_CANLF
Taste receptor type 2
Search

0.55	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0050907	detection of chemical stimulus involved in sensory perception
0.36	GO:0032467	positive regulation of cytokinesis

0.72	GO:0004930	G-protein coupled receptor activity
0.54	GO:0033038	bitter taste receptor activity

0.30

GO:0044425

membrane part

tr|Q2ABE0|Q2ABE0_CANLF
Taste receptor type 2
Search

TAS2R1

0.65	Taste receptor type 2 member 1

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.65	GO:0033038	bitter taste receptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q2KL21|EPOR_CANLF
Erythropoietin receptor
Search

EPOR

0.97	Erythropoietin receptor

0.77	GO:0019221	cytokine-mediated signaling pathway
0.72	GO:0036018	cellular response to erythropoietin
0.69	GO:0046697	decidualization
0.63	GO:0007507	heart development
0.62	GO:0007420	brain development
0.39	GO:1904374	cellular response to kainic acid
0.38	GO:0030154	cell differentiation
0.38	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.38	GO:1903206	negative regulation of hydrogen peroxide-induced cell death
0.37	GO:0060415	muscle tissue morphogenesis

0.79	GO:0004896	cytokine receptor activity
0.59	GO:0042802	identical protein binding
0.36	GO:0005085	guanyl-nucleotide exchange factor activity

0.37	GO:0005576	extracellular region
0.37	GO:0009897	external side of plasma membrane
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

tr|Q2KM13|Q2KM13_CANLF
Eukaryotic translation initiation factor 2-alpha kinase 2
Search

EIF2AK2

0.92	Interferon-induced double-stranded RNA-activated protein kinase

0.85	GO:0045071	negative regulation of viral genome replication
0.85	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation
0.78	GO:0008285	negative regulation of cell proliferation
0.78	GO:0045087	innate immune response
0.77	GO:0009615	response to virus
0.74	GO:0042981	regulation of apoptotic process
0.67	GO:0009636	response to toxic substance
0.57	GO:0035455	response to interferon-alpha
0.57	GO:0033688	regulation of osteoblast proliferation
0.56	GO:1902033	regulation of hematopoietic stem cell proliferation

0.76	GO:0003725	double-stranded RNA binding
0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0045182	translation regulator activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.52	GO:0003743	translation initiation factor activity
0.50	GO:0042802	identical protein binding
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.53	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|Q2KM14|Q2KM14_CANLF
Oligoadenylate synthetase-like 2
Search

0.85	Oligoadenylate synthetase 1

0.75	GO:0051607	defense response to virus
0.71	GO:0006955	immune response
0.58	GO:0045071	negative regulation of viral genome replication
0.43	GO:0060700	regulation of ribonuclease activity
0.43	GO:0042593	glucose homeostasis
0.41	GO:0035457	cellular response to interferon-alpha
0.41	GO:0006006	glucose metabolic process
0.40	GO:0006164	purine nucleotide biosynthetic process

0.74	GO:0003725	double-stranded RNA binding
0.58	GO:0016779	nucleotidyltransferase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003677	DNA binding
0.37	GO:0008270	zinc ion binding

0.46	GO:0005829	cytosol
0.44	GO:0005730	nucleolus
0.43	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.58

EC:2.7.7

GO:0016779

tr|Q2KM15|Q2KM15_CANLF
2'-5' oligoadenylate synthetase-like 1
Search

OASL

0.80	2'-5'-oligoadenylate synthetase like

0.78	GO:0051607	defense response to virus
0.74	GO:0006955	immune response
0.73	GO:0045071	negative regulation of viral genome replication
0.42	GO:0018377	protein myristoylation
0.40	GO:0043413	macromolecule glycosylation
0.40	GO:0009101	glycoprotein biosynthetic process
0.39	GO:0006401	RNA catabolic process

0.77	GO:0003725	double-stranded RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0016740	transferase activity
0.49	GO:0003677	DNA binding

0.63	GO:0005730	nucleolus
0.62	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.41	GO:0048471	perinuclear region of cytoplasm

0.51

GO:0016740

sp|Q2KNA0|CYTSA_CANLF
Cytospin-A
Search

SPECC1L

0.85	Sperm antigen with calponin homology and coiled-coil domains 1 like

0.62	GO:0007155	cell adhesion
0.56	GO:0051301	cell division
0.56	GO:0007049	cell cycle
0.50	GO:0007026	negative regulation of microtubule depolymerization
0.48	GO:0097095	frontonasal suture morphogenesis
0.48	GO:0030835	negative regulation of actin filament depolymerization
0.47	GO:0060325	face morphogenesis
0.46	GO:0016477	cell migration
0.46	GO:0035023	regulation of Rho protein signal transduction
0.45	GO:0043547	positive regulation of GTPase activity

0.46	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.45	GO:0005096	GTPase activator activity
0.44	GO:0004674	protein serine/threonine kinase activity

0.66	GO:0005921	gap junction
0.65	GO:0005856	cytoskeleton
0.58	GO:0005829	cytosol
0.49	GO:0044446	intracellular organelle part
0.44	GO:0099512	supramolecular fiber
0.40	GO:0043234	protein complex

0.44

GO:0004674

sp|Q2LEC2|CRBB2_CANLF
Beta-crystallin B2
Search

CRYBB2

0.97	Beta B2-crystallin short isoform

0.73	GO:0007601	visual perception
0.53	GO:0043010	camera-type eye development
0.34	GO:0006468	protein phosphorylation
0.34	GO:0050896	response to stimulus
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.33	GO:0050789	regulation of biological process

0.80	GO:0005212	structural constituent of eye lens
0.51	GO:0042803	protein homodimerization activity
0.38	GO:0047696	beta-adrenergic receptor kinase activity
0.36	GO:0004703	G-protein coupled receptor kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38

EC:2.7.11.15

GO:0047696

sp|Q2PQH8|GDE_CANLF
Glycogen debranching enzyme
Search

AGL

0.56	Glycogen debranching enzyme

0.80	GO:0005980	glycogen catabolic process
0.75	GO:0005978	glycogen biosynthetic process
0.40	GO:0051384	response to glucocorticoid
0.39	GO:0007584	response to nutrient
0.35	GO:0043312	neutrophil degranulation

0.84	GO:0004135	amylo-alpha-1,6-glucosidase activity
0.80	GO:0004134	4-alpha-glucanotransferase activity
0.56	GO:0031593	polyubiquitin modification-dependent protein binding
0.52	GO:0001871	pattern binding
0.49	GO:0030246	carbohydrate binding
0.39	GO:0102500	beta-maltose 4-alpha-glucanotransferase activity

0.55	GO:0016234	inclusion body
0.45	GO:0005634	nucleus
0.40	GO:0016529	sarcoplasmic reticulum
0.36	GO:0043033	isoamylase complex
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005829	cytosol
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:3.2.1.33

GO:0004135

sp|Q2PT31|MYOC_CANLF
Myocilin
Search

MYOC

0.97	Myocilin, trabecular meshwork-inducible glucocorticoid response

0.84	GO:0051492	regulation of stress fiber assembly
0.84	GO:0001952	regulation of cell-matrix adhesion
0.80	GO:0030335	positive regulation of cell migration
0.65	GO:0038133	ERBB2-ERBB3 signaling pathway
0.65	GO:0014734	skeletal muscle hypertrophy
0.63	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade
0.63	GO:0051901	positive regulation of mitochondrial depolarization
0.62	GO:0045162	clustering of voltage-gated sodium channels
0.61	GO:0032232	negative regulation of actin filament bundle assembly
0.61	GO:1903393	positive regulation of adherens junction organization

0.61	GO:0032027	myosin light chain binding
0.60	GO:0001968	fibronectin binding
0.59	GO:0005109	frizzled binding
0.58	GO:0030971	receptor tyrosine kinase binding
0.37	GO:0004930	G-protein coupled receptor activity
0.37	GO:0046872	metal ion binding
0.37	GO:0030246	carbohydrate binding
0.35	GO:0045296	cadherin binding
0.34	GO:0042803	protein homodimerization activity

0.72	GO:0005615	extracellular space
0.62	GO:0033268	node of Ranvier
0.56	GO:0005758	mitochondrial intermembrane space
0.55	GO:0005741	mitochondrial outer membrane
0.53	GO:0031012	extracellular matrix
0.53	GO:0031410	cytoplasmic vesicle
0.52	GO:0005794	Golgi apparatus
0.52	GO:0005783	endoplasmic reticulum
0.47	GO:0019866	organelle inner membrane
0.44	GO:1903561	extracellular vesicle

tr|Q2Q420|Q2Q420_CANLF
EMR3
Search

ADGRE3

0.96	LOW QUALITY PROTEIN: EGF-like module-containing mucin-like hormone receptor-like 3

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.71	GO:0007166	cell surface receptor signaling pathway
0.43	GO:0071621	granulocyte chemotaxis
0.42	GO:0043304	regulation of mast cell degranulation
0.40	GO:0007155	cell adhesion
0.37	GO:0006954	inflammatory response
0.36	GO:0043312	neutrophil degranulation
0.33	GO:0007264	small GTPase mediated signal transduction
0.32	GO:0065009	regulation of molecular function
0.32	GO:0006355	regulation of transcription, DNA-templated

0.72	GO:0004930	G-protein coupled receptor activity
0.65	GO:0005509	calcium ion binding
0.44	GO:0035374	chondroitin sulfate binding
0.33	GO:0005085	guanyl-nucleotide exchange factor activity
0.31	GO:0003676	nucleic acid binding

0.42	GO:0031256	leading edge membrane
0.37	GO:0001726	ruffle
0.37	GO:0031253	cell projection membrane
0.37	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0009986	cell surface
0.35	GO:0005576	extracellular region
0.34	GO:0005639	integral component of nuclear inner membrane

sp|Q2Q421|AGRE2_CANLF
Adhesion G protein-coupled receptor E2
Search

ADGRE2

0.94	Adhesion G protein-coupled receptor E2

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0071621	granulocyte chemotaxis
0.45	GO:0043304	regulation of mast cell degranulation
0.43	GO:0007155	cell adhesion
0.40	GO:0006954	inflammatory response
0.37	GO:0043312	neutrophil degranulation
0.34	GO:0007267	cell-cell signaling
0.32	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.32	GO:0006355	regulation of transcription, DNA-templated

0.72	GO:0004930	G-protein coupled receptor activity
0.66	GO:0005509	calcium ion binding
0.49	GO:0035374	chondroitin sulfate binding
0.33	GO:0005515	protein binding
0.32	GO:0004984	olfactory receptor activity
0.31	GO:0003676	nucleic acid binding

0.46	GO:0031256	leading edge membrane
0.40	GO:0001726	ruffle
0.40	GO:0031253	cell projection membrane
0.36	GO:0030667	secretory granule membrane
0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.34	GO:0101002	ficolin-1-rich granule
0.34	GO:0070820	tertiary granule
0.34	GO:0005639	integral component of nuclear inner membrane
0.34	GO:0005887	integral component of plasma membrane

tr|Q2Q423|Q2Q423_CANLF
CD97 large isoform
Search

ADGRE5

0.97	Adhesion G protein-coupled receptor E5

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.71	GO:0007166	cell surface receptor signaling pathway
0.43	GO:0071621	granulocyte chemotaxis
0.42	GO:0007155	cell adhesion
0.41	GO:0043304	regulation of mast cell degranulation
0.39	GO:0006954	inflammatory response
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0051965	positive regulation of synapse assembly
0.35	GO:0007267	cell-cell signaling
0.34	GO:0006468	protein phosphorylation

0.72	GO:0004930	G-protein coupled receptor activity
0.69	GO:0005509	calcium ion binding
0.44	GO:0035374	chondroitin sulfate binding
0.37	GO:0017049	GTP-Rho binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0005524	ATP binding
0.32	GO:0004984	olfactory receptor activity
0.32	GO:0005201	extracellular matrix structural constituent
0.31	GO:0030247	polysaccharide binding

0.42	GO:0031256	leading edge membrane
0.38	GO:0001726	ruffle
0.38	GO:0031253	cell projection membrane
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0030667	secretory granule membrane
0.34	GO:0005887	integral component of plasma membrane
0.31	GO:0005578	proteinaceous extracellular matrix

0.35

GO:0004674

sp|Q2TFN9|HSP74_CANLF
Heat shock 70 kDa protein 4
Search

HSPA4

0.94	Epididymis secretory sperm binding protein Li 5a

0.55	GO:0045040	protein import into mitochondrial outer membrane
0.54	GO:0051131	chaperone-mediated protein complex assembly
0.35	GO:0043392	negative regulation of DNA binding
0.35	GO:0032092	positive regulation of protein binding
0.35	GO:0045766	positive regulation of angiogenesis
0.35	GO:0006986	response to unfolded protein
0.35	GO:0001822	kidney development
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0009408	response to heat
0.34	GO:0001933	negative regulation of protein phosphorylation

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0046872	metal ion binding

0.53	GO:0070062	extracellular exosome
0.47	GO:0005829	cytosol
0.35	GO:0005811	lipid droplet
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q2THW8|ZDHC8_CANLF
Probable palmitoyltransferase ZDHHC8
Search

ZDHHC8

0.57	Palmitoyltransferase

0.85	GO:0018345	protein palmitoylation
0.57	GO:1903146	regulation of autophagy of mitochondrion
0.56	GO:1903955	positive regulation of protein targeting to mitochondrion
0.53	GO:0007626	locomotory behavior
0.37	GO:0034380	high-density lipoprotein particle assembly

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0005515	protein binding

0.51	GO:0005794	Golgi apparatus
0.44	GO:0005739	mitochondrion
0.40	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005829	cytosol
0.34	GO:0030425	dendrite
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.3.1.225

GO:0019706

sp|Q2THW9|ZDHC5_CANLF
Palmitoyltransferase ZDHHC5
Search

ZDHHC5

0.54	Palmitoyltransferase

0.65	GO:0018345	protein palmitoylation
0.37	GO:1903146	regulation of autophagy of mitochondrion
0.37	GO:1903955	positive regulation of protein targeting to mitochondrion
0.36	GO:0007626	locomotory behavior
0.32	GO:0045454	cell redox homeostasis

0.79	GO:0019707	protein-cysteine S-acyltransferase activity
0.79	GO:0016409	palmitoyltransferase activity
0.33	GO:0005515	protein binding

0.55	GO:0030425	dendrite
0.44	GO:0005886	plasma membrane
0.37	GO:0005737	cytoplasm
0.36	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.79

EC:2.3.1

GO:0019707

sp|Q2TLZ1|MACOI_CANLF
Macoilin
Search

TMEM57

0.96	Transmembrane protein 57

0.61	GO:0023041	neuronal signal transduction
0.52	GO:0007420	brain development

0.56	GO:0030867	rough endoplasmic reticulum membrane
0.55	GO:0044306	neuron projection terminus
0.54	GO:0031965	nuclear membrane
0.53	GO:0030424	axon
0.51	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

tr|Q2VCE2|Q2VCE2_CANLF
Interleukin-1 beta
Search

IL1B

0.46	Interleukin-1 beta

0.86	GO:0001660	fever generation
0.84	GO:0051781	positive regulation of cell division
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.59	GO:0035504	regulation of myosin light chain kinase activity
0.58	GO:0070487	monocyte aggregation
0.58	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity
0.57	GO:0030730	sequestering of triglyceride
0.57	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.57	GO:0045086	positive regulation of interleukin-2 biosynthetic process

0.86	GO:0005149	interleukin-1 receptor binding
0.80	GO:0005125	cytokine activity
0.50	GO:0019904	protein domain specific binding

0.83	GO:0005776	autophagosome
0.81	GO:0070062	extracellular exosome
0.78	GO:0005764	lysosome
0.72	GO:0031410	cytoplasmic vesicle
0.68	GO:0005829	cytosol
0.41	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|Q2VLG6|C163A_CANLF
Scavenger receptor cysteine-rich type 1 protein M130
Search

0.10	Scavenger receptor cysteine-rich type 1 protein M130

0.72	GO:0006898	receptor-mediated endocytosis
0.43	GO:0002365	gamma-delta T cell lineage commitment
0.41	GO:0032620	interleukin-17 production
0.30	GO:0006950	response to stress

0.81

GO:0005044

scavenger receptor activity

0.39	GO:0009897	external side of plasma membrane
0.39	GO:0005576	extracellular region
0.38	GO:0005903	brush border
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q2XNS1|RN141_CANLF
RING finger protein 141
Search

RNF141

0.73	RING finger protein 141

0.83	GO:0051865	protein autoubiquitination
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.32	GO:0016310	phosphorylation
0.32	GO:0006281	DNA repair

0.72	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0003677	DNA binding
0.41	GO:0046872	metal ion binding
0.34	GO:0016874	ligase activity
0.32	GO:0016301	kinase activity

0.32	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.34	EC:6	GO:0016874
0.72	KEGG:R03876	GO:0004842

tr|Q2XPT7|Q2XPT7_CANLF
VEGFR2
Search

KDR

0.58	Vascular endothelial growth factor receptor

0.85	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.85	GO:0038084	vascular endothelial growth factor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.66	GO:1904881	cellular response to hydrogen sulfide
0.64	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
0.64	GO:0051901	positive regulation of mitochondrial depolarization
0.63	GO:2001028	positive regulation of endothelial cell chemotaxis
0.62	GO:0090141	positive regulation of mitochondrial fission
0.62	GO:0050927	positive regulation of positive chemotaxis
0.62	GO:0051894	positive regulation of focal adhesion assembly

0.85	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.80	GO:0019838	growth factor binding
0.60	GO:0005178	integrin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0042802	identical protein binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.36	GO:0051879	Hsp90 protein binding
0.36	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity

0.58	GO:0098857	membrane microdomain
0.55	GO:0005768	endosome
0.53	GO:0005794	Golgi apparatus
0.53	GO:0005783	endoplasmic reticulum
0.51	GO:0005887	integral component of plasma membrane
0.39	GO:0030054	cell junction
0.37	GO:0009897	external side of plasma membrane
0.36	GO:0005634	nucleus
0.35	GO:0005576	extracellular region
0.35	GO:0043025	neuronal cell body

0.36

EC:2.7.10

GO:0004716

tr|Q2Z1P8|Q2Z1P8_CANLF
Anion exchange protein
Search

SLC4A1

0.64	Anion exchange protein (Fragment)

0.69	GO:0015698	inorganic anion transport
0.68	GO:0098656	anion transmembrane transport
0.60	GO:0015701	bicarbonate transport
0.50	GO:0051453	regulation of intracellular pH
0.47	GO:0098660	inorganic ion transmembrane transport
0.45	GO:0006814	sodium ion transport
0.41	GO:0098655	cation transmembrane transport
0.36	GO:0010037	response to carbon dioxide
0.36	GO:0010446	response to alkaline pH
0.36	GO:0014823	response to activity

0.82	GO:0005452	inorganic anion exchanger activity
0.60	GO:0015106	bicarbonate transmembrane transporter activity
0.59	GO:0015301	anion:anion antiporter activity
0.58	GO:0030506	ankyrin binding
0.53	GO:0015108	chloride transmembrane transporter activity
0.51	GO:0042803	protein homodimerization activity
0.46	GO:0015296	anion:cation symporter activity
0.45	GO:0015081	sodium ion transmembrane transporter activity
0.36	GO:0043495	protein membrane anchor
0.35	GO:0008022	protein C-terminus binding

0.56	GO:0016323	basolateral plasma membrane
0.55	GO:0030863	cortical cytoskeleton
0.49	GO:0005887	integral component of plasma membrane
0.43	GO:0030018	Z disc
0.38	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome
0.35	GO:0014704	intercalated disc
0.34	GO:0009986	cell surface
0.34	GO:0016324	apical plasma membrane

tr|Q30437|Q30437_CANLF
MHC class II DR alpha chain
Search

0.39	Mamu class II histocompatibility antigen, DR alpha chain

0.83	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.74	GO:0006955	immune response
0.49	GO:0065006	protein-carbohydrate complex assembly
0.49	GO:0002399	MHC class II protein complex assembly
0.49	GO:0002501	peptide antigen assembly with MHC protein complex
0.45	GO:0050890	cognition
0.35	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.35	GO:0031295	T cell costimulation
0.35	GO:0050852	T cell receptor signaling pathway
0.34	GO:0019221	cytokine-mediated signaling pathway

0.47	GO:0042605	peptide antigen binding
0.35	GO:0032395	MHC class II receptor activity
0.35	GO:0023026	MHC class II protein complex binding

0.76	GO:0042613	MHC class II protein complex
0.45	GO:0031902	late endosome membrane
0.45	GO:0005765	lysosomal membrane
0.43	GO:0009986	cell surface
0.35	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.35	GO:0032588	trans-Golgi network membrane
0.34	GO:0030669	clathrin-coated endocytic vesicle membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0012507	ER to Golgi transport vesicle membrane
0.33	GO:0005887	integral component of plasma membrane

sp|Q30DN6|KDM5D_CANLF
Lysine-specific demethylase 5D
Search

KDM5C

0.96	Jumonji AT rich interactive domain 1D

0.57	GO:0034720	histone H3-K4 demethylation
0.52	GO:0032259	methylation
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0060765	regulation of androgen receptor signaling pathway
0.40	GO:0002457	T cell antigen processing and presentation
0.39	GO:0043524	negative regulation of neuron apoptotic process
0.37	GO:0048511	rhythmic process
0.37	GO:0009636	response to toxic substance
0.36	GO:0032012	regulation of ARF protein signal transduction
0.36	GO:0055114	oxidation-reduction process

0.58	GO:0032453	histone demethylase activity (H3-K4 specific)
0.54	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.53	GO:0008168	methyltransferase activity
0.40	GO:0050681	androgen receptor binding
0.40	GO:0051213	dioxygenase activity
0.36	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.35	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.42	GO:0044446	intracellular organelle part
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0008168

tr|Q30KR2|Q30KR2_CANLF
Sperm-associated antigen 11 variant E
Search

0.96	Sperm-associated antigen 11 variant E

0.71	GO:0006952	defense response
0.48	GO:0009617	response to bacterium

0.66	GO:0005576	extracellular region
0.44	GO:0001669	acrosomal vesicle

tr|Q30KR3|Q30KR3_CANLF
Sperm-associated antigen 11 variant C
Search

0.95	Sperm-associated antigen 11 variant C

0.70	GO:0006952	defense response
0.53	GO:0006955	immune response
0.49	GO:0051715	cytolysis in other organism
0.45	GO:0051707	response to other organism

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|Q30KS5|Q30KS5_CANLF
Beta-defensin 129
Search

DEFB129

0.68	Beta-defensin

0.79	GO:0045087	innate immune response
0.66	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.51	GO:0009986	cell surface

tr|Q30KS6|Q30KS6_CANLF
Beta-defensin
Search

DEFB128

0.63	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium
0.65	GO:0031640	killing of cells of other organism

0.66	GO:0005576	extracellular region
0.51	GO:0009986	cell surface

tr|Q30KS7|Q30KS7_CANLF
Beta-defensin
Search

DEFB127

0.62	Beta-defensin

0.79	GO:0045087	innate immune response
0.76	GO:0042742	defense response to bacterium
0.69	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

0.37

GO:0005515

protein binding

0.66	GO:0005576	extracellular region
0.47	GO:0009986	cell surface

tr|Q30KS9|Q30KS9_CANLF
Beta-defensin
Search

DEFB125

0.64	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.53	GO:0009986	cell surface

tr|Q30KT0|Q30KT0_CANLF
Beta-defensin
Search

DEFB124

0.64	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium
0.42	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion
0.41	GO:2001184	positive regulation of interleukin-12 secretion
0.41	GO:0071224	cellular response to peptidoglycan
0.41	GO:1900042	positive regulation of interleukin-2 secretion
0.41	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.41	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.41	GO:0090197	positive regulation of chemokine secretion
0.41	GO:2000778	positive regulation of interleukin-6 secretion

0.66	GO:0005576	extracellular region
0.55	GO:0009986	cell surface
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|Q30KT1|Q30KT1_CANLF
Beta-defensin
Search

DEFB123

0.71	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.55	GO:0009986	cell surface

tr|Q30KT2|Q30KT2_CANLF
Beta-defensin
Search

0.62	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium
0.36	GO:0031640	killing of cells of other organism

0.66	GO:0005576	extracellular region
0.55	GO:0009986	cell surface

tr|Q30KT3|Q30KT3_CANLF
Beta-defensin
Search

DEFB121

0.45	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.59	GO:0009986	cell surface

sp|Q30KT5|DB119_CANLF
Beta-defensin 119
Search

DEFB119

0.67	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium
0.41	GO:0050832	defense response to fungus

0.41

GO:0001530

lipopolysaccharide binding

0.66	GO:0005576	extracellular region
0.55	GO:0009986	cell surface

tr|Q30KT6|Q30KT6_CANLF
Beta-defensin
Search

DEFB118

0.64	Beta-defensin

0.79	GO:0045087	innate immune response
0.75	GO:0042742	defense response to bacterium
0.69	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.63	GO:0031640	killing of cells of other organism
0.60	GO:0051673	membrane disruption in other organism
0.47	GO:0007160	cell-matrix adhesion
0.46	GO:0007283	spermatogenesis

0.66	GO:0005576	extracellular region
0.54	GO:0009986	cell surface

tr|Q30KT8|Q30KT8_CANLF
Beta-defensin
Search

DEFB116

0.56	Beta-defensin

0.79	GO:0045087	innate immune response
0.75	GO:0042742	defense response to bacterium

0.66	GO:0005576	extracellular region
0.59	GO:0009986	cell surface

tr|Q30KU2|Q30KU2_CANLF
Beta-defensin
Search

DEFB110

0.64	Beta-defensin

0.79	GO:0045087	innate immune response
0.76	GO:0042742	defense response to bacterium
0.38	GO:0060046	regulation of acrosome reaction
0.38	GO:0007339	binding of sperm to zona pellucida
0.35	GO:0065009	regulation of molecular function

0.37

GO:0005246

calcium channel regulator activity

0.66	GO:0005576	extracellular region
0.53	GO:0009986	cell surface
0.30	GO:0044425	membrane part

sp|Q30KU3|DB110_CANLF
Beta-defensin 110
Search

DEFB110

0.63	Beta-defensin

0.79	GO:0045087	innate immune response
0.71	GO:0042742	defense response to bacterium
0.38	GO:0060046	regulation of acrosome reaction
0.38	GO:0007339	binding of sperm to zona pellucida
0.35	GO:0065009	regulation of molecular function

0.38

GO:0005246

calcium channel regulator activity

0.66	GO:0005576	extracellular region
0.51	GO:0009986	cell surface
0.30	GO:0044425	membrane part

tr|Q30KV0|Q30KV0_CANLF
Beta-defensin 103
Search

0.92	Prepro-beta-defensin 3

0.72	GO:0006952	defense response
0.57	GO:0050918	positive chemotaxis
0.57	GO:0009617	response to bacterium
0.54	GO:0060326	cell chemotaxis
0.43	GO:0031640	killing of cells of other organism
0.40	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.40	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.39	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.39	GO:0019933	cAMP-mediated signaling
0.38	GO:0009620	response to fungus

0.58	GO:0042056	chemoattractant activity
0.40	GO:0031731	CCR6 chemokine receptor binding
0.37	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.40	GO:0005796	Golgi lumen
0.39	GO:0097225	sperm midpiece
0.37	GO:0019898	extrinsic component of membrane
0.37	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

tr|Q30KV1|Q30KV1_CANLF
Beta-defensin 102
Search

0.48	Beta-defensin 102

0.72

GO:0006952

defense response

0.66

GO:0005576

extracellular region

tr|Q30KV2|Q30KV2_CANLF
Beta-defensin 1
Search

DEFB1

0.89	Beta-defensin 1

0.72	GO:0006952	defense response
0.66	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.63	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.60	GO:0019933	cAMP-mediated signaling
0.60	GO:0002385	mucosal immune response
0.59	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.56	GO:0009617	response to bacterium
0.41	GO:0006935	chemotaxis
0.41	GO:0007186	G-protein coupled receptor signaling pathway

0.66	GO:0031731	CCR6 chemokine receptor binding
0.55	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.63	GO:0097225	sperm midpiece
0.55	GO:0019898	extrinsic component of membrane
0.54	GO:0031982	vesicle
0.46	GO:0005796	Golgi lumen

sp|Q32KH0|ARSK_CANLF
Arylsulfatase K
Search

ARSK

0.97	Arylsulfatase K

0.35	GO:0006687	glycosphingolipid metabolic process
0.35	GO:0043687	post-translational protein modification
0.31	GO:0030203	glycosaminoglycan metabolic process

0.74	GO:0008484	sulfuric ester hydrolase activity
0.36	GO:0046872	metal ion binding
0.31	GO:0016740	transferase activity

0.39	GO:0005576	extracellular region
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0008484

tr|Q32KH1|Q32KH1_CANLF
Sulfatase 2
Search

SULF2

0.94	Extracellular sulfatase Sulf-2

0.60	GO:0014846	esophagus smooth muscle contraction
0.59	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway
0.58	GO:2000345	regulation of hepatocyte proliferation
0.58	GO:0035413	positive regulation of catenin import into nucleus
0.58	GO:0097421	liver regeneration
0.58	GO:0032836	glomerular basement membrane development
0.58	GO:0003094	glomerular filtration
0.58	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.57	GO:0010575	positive regulation of vascular endothelial growth factor production
0.57	GO:0060384	innervation

0.74	GO:0008484	sulfuric ester hydrolase activity
0.66	GO:0005509	calcium ion binding
0.33	GO:0046983	protein dimerization activity

0.71	GO:0009986	cell surface
0.67	GO:0005794	Golgi apparatus
0.67	GO:0005783	endoplasmic reticulum
0.42	GO:0005886	plasma membrane
0.35	GO:0005615	extracellular space
0.35	GO:0031984	organelle subcompartment
0.33	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0008484

sp|Q32KH5|GALNS_CANLF
N-acetylgalactosamine-6-sulfatase
Search

GALNS

0.83	N-acetylgalactosamine-6-sulfatase

0.36	GO:0042340	keratan sulfate catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0019083	viral transcription
0.33	GO:0001172	transcription, RNA-templated
0.33	GO:0009116	nucleoside metabolic process

0.83	GO:0043890	N-acetylgalactosamine-6-sulfatase activity
0.36	GO:0003943	N-acetylgalactosamine-4-sulfatase activity
0.35	GO:0046872	metal ion binding
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.32	GO:0003723	RNA binding

0.39	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen

0.83

EC:3.1.6.4

GO:0043890

tr|Q32KH6|Q32KH6_CANLF
Arylsulfatase J
Search

ARSJ

0.97	Arylsulfatase J

0.35	GO:0006687	glycosphingolipid metabolic process
0.35	GO:0043687	post-translational protein modification

0.74	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0046872	metal ion binding

0.36	GO:0005576	extracellular region
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.74

GO:0008484

sp|Q32KH7|ARSI_CANLF
Arylsulfatase I
Search

ARSI

0.97	Arylsulfatase I

0.36	GO:0006687	glycosphingolipid metabolic process
0.36	GO:0043687	post-translational protein modification

0.74	GO:0008484	sulfuric ester hydrolase activity
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0005576	extracellular region
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0008484

sp|Q32KH8|ARSH_CANLF
Arylsulfatase H
Search

ARSH

0.45	Arylsulfatase H

0.39	GO:0006687	glycosphingolipid metabolic process
0.39	GO:0043687	post-translational protein modification
0.34	GO:0001501	skeletal system development

0.73	GO:0008484	sulfuric ester hydrolase activity
0.35	GO:0046872	metal ion binding

0.43	GO:0005794	Golgi apparatus
0.39	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0070062	extracellular exosome
0.34	GO:0031984	organelle subcompartment
0.34	GO:0005764	lysosome
0.30	GO:0044425	membrane part

0.73

GO:0008484

sp|Q32KH9|ARSG_CANLF
Arylsulfatase G
Search

ARSG

0.97	Arylsulfatase G

0.47	GO:0006790	sulfur compound metabolic process
0.36	GO:0006687	glycosphingolipid metabolic process
0.35	GO:0043687	post-translational protein modification

0.75	GO:0008484	sulfuric ester hydrolase activity
0.35	GO:0046872	metal ion binding

0.54	GO:0005764	lysosome
0.51	GO:0005615	extracellular space
0.50	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.75

GO:0008484

tr|Q32KI1|Q32KI1_CANLF
Arylsulfatase E
Search

ARSE

0.45	Arylsulfatase E

0.38	GO:0006687	glycosphingolipid metabolic process
0.38	GO:0043687	post-translational protein modification
0.35	GO:0001501	skeletal system development

0.73	GO:0008484	sulfuric ester hydrolase activity
0.35	GO:0046872	metal ion binding

0.45	GO:0005794	Golgi apparatus
0.38	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

0.73

GO:0008484

tr|Q32KI4|Q32KI4_CANLF
Arylsulfatase B
Search

ARSB

0.89	Arylsulfatase B

0.60	GO:0061580	colon epithelial cell migration
0.54	GO:0010632	regulation of epithelial cell migration
0.42	GO:0010976	positive regulation of neuron projection development
0.41	GO:0051597	response to methylmercury
0.40	GO:0043627	response to estrogen
0.40	GO:0009268	response to pH
0.39	GO:0007584	response to nutrient
0.39	GO:0007417	central nervous system development
0.38	GO:0006914	autophagy
0.36	GO:0030207	chondroitin sulfate catabolic process

0.74	GO:0008484	sulfuric ester hydrolase activity
0.35	GO:0046872	metal ion binding
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0005515	protein binding

0.41	GO:0005764	lysosome
0.40	GO:0009986	cell surface
0.39	GO:0005791	rough endoplasmic reticulum
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005576	extracellular region
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.36	GO:0005739	mitochondrion
0.36	GO:0005775	vacuolar lumen

0.74

GO:0008484

sp|Q34101|CYB_CANLF
Cytochrome b
Search

CYTB

0.41	Cytochrome b

0.72

GO:0006122

mitochondrial electron transport, ubiquinol to cytochrome c

0.72	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding

0.71	GO:0045275	respiratory chain complex III
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.35	GO:0031301	integral component of organelle membrane

0.72

EC:1.10.2

GO:0016681

sp|Q38HS3|KLRD1_CANLF
Natural killer cells antigen CD94
Search

KLRD1

0.96	Killer cell lectin like receptor D1

0.59	GO:0002228	natural killer cell mediated immunity
0.36	GO:0050776	regulation of immune response
0.36	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.62	GO:0023024	MHC class I protein complex binding
0.61	GO:0023025	MHC class Ib protein complex binding
0.61	GO:0023029	MHC class Ib protein binding
0.61	GO:1990405	protein antigen binding
0.36	GO:0099600	transmembrane receptor activity
0.35	GO:0038023	signaling receptor activity

0.53	GO:0043235	receptor complex
0.51	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q38IV1|Q38IV1_CANLF
Baculoviral IAP-repeat containing protein 4
Search

XIAP

0.93	Baculoviral IAP-repeat containing protein 4

0.80	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process
0.73	GO:0006915	apoptotic process
0.72	GO:0070997	neuron death
0.71	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.69	GO:1902530	positive regulation of protein linear polyubiquitination
0.63	GO:0016567	protein ubiquitination
0.57	GO:0090307	mitotic spindle assembly
0.50	GO:0006974	cellular response to DNA damage stimulus
0.40	GO:0006518	peptide metabolic process
0.40	GO:0043604	amide biosynthetic process

0.74	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.63	GO:0004842	ubiquitin-protein transferase activity
0.56	GO:0042802	identical protein binding
0.41	GO:0003735	structural constituent of ribosome
0.41	GO:0016874	ligase activity
0.40	GO:0046872	metal ion binding

0.54	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0043233	organelle lumen
0.36	GO:0045121	membrane raft
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043234	protein complex

0.41	EC:6	GO:0016874
0.63	KEGG:R03876	GO:0004842

sp|Q38JA7|KDM5C_CANLF
Lysine-specific demethylase 5C
Search

KDM5C

0.96	Jumonji AT rich interactive domain 1D

0.58	GO:0034720	histone H3-K4 demethylation
0.53	GO:0032259	methylation
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0060765	regulation of androgen receptor signaling pathway
0.40	GO:0002457	T cell antigen processing and presentation
0.38	GO:0043524	negative regulation of neuron apoptotic process
0.38	GO:0048511	rhythmic process
0.38	GO:0009636	response to toxic substance
0.36	GO:0055114	oxidation-reduction process
0.36	GO:0006351	transcription, DNA-templated

0.59	GO:0032453	histone demethylase activity (H3-K4 specific)
0.54	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.53	GO:0008168	methyltransferase activity
0.40	GO:0050681	androgen receptor binding
0.39	GO:0051213	dioxygenase activity
0.37	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.35	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.42	GO:0044446	intracellular organelle part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0008168

tr|Q38JA9|Q38JA9_CANLF
Caspase 8
Search

CASP8

0.91	Caspase 8 splice variant

0.77	GO:0006915	apoptotic process
0.73	GO:0042981	regulation of apoptotic process
0.61	GO:0045651	positive regulation of macrophage differentiation
0.61	GO:0097202	activation of cysteine-type endopeptidase activity
0.59	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.59	GO:0071260	cellular response to mechanical stimulus
0.58	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0034612	response to tumor necrosis factor
0.52	GO:0007166	cell surface receptor signaling pathway
0.52	GO:0051603	proteolysis involved in cellular protein catabolic process

0.75	GO:0004197	cysteine-type endopeptidase activity
0.64	GO:0035877	death effector domain binding
0.60	GO:0097110	scaffold protein binding
0.56	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0042802	identical protein binding
0.51	GO:0004871	signal transducer activity
0.38	GO:0005123	death receptor binding
0.37	GO:0005164	tumor necrosis factor receptor binding
0.36	GO:0032403	protein complex binding
0.36	GO:0046982	protein heterodimerization activity

0.67	GO:0097342	ripoptosome
0.63	GO:0031265	CD95 death-inducing signaling complex
0.51	GO:0005654	nucleoplasm
0.38	GO:0030690	Noc1p-Noc2p complex
0.37	GO:0044297	cell body
0.37	GO:0098857	membrane microdomain
0.37	GO:0043005	neuron projection
0.35	GO:0005739	mitochondrion
0.35	GO:0031968	organelle outer membrane
0.34	GO:0005856	cytoskeleton

0.75

EC:3.4.22

GO:0004197

sp|Q3BCQ4|RHCG_CANLF
Ammonium transporter Rh type C
Search

RHCG

0.85	Rhesus blood group-associated glycoprotein C

0.77	GO:0072488	ammonium transmembrane transport
0.61	GO:0070634	transepithelial ammonium transport
0.52	GO:0006885	regulation of pH
0.51	GO:0006873	cellular ion homeostasis
0.47	GO:0015695	organic cation transport
0.42	GO:0097272	ammonia homeostasis
0.36	GO:0006814	sodium ion transport
0.35	GO:0015837	amine transport
0.34	GO:0030855	epithelial cell differentiation

0.77	GO:0008519	ammonium transmembrane transporter activity
0.59	GO:0030506	ankyrin binding
0.50	GO:0042802	identical protein binding

0.57	GO:0016324	apical plasma membrane
0.56	GO:0016323	basolateral plasma membrane
0.49	GO:0005887	integral component of plasma membrane
0.41	GO:0031410	cytoplasmic vesicle
0.36	GO:0016327	apicolateral plasma membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0012506	vesicle membrane
0.35	GO:0045178	basal part of cell
0.34	GO:0044446	intracellular organelle part

sp|Q3BCQ5|RHAG_CANLF
Ammonium transporter Rh type A
Search

RHAG

0.96	Ammonium transporter Rh type A

0.77	GO:0072488	ammonium transmembrane transport
0.59	GO:0015670	carbon dioxide transport
0.55	GO:0060586	multicellular organismal iron ion homeostasis
0.54	GO:0048821	erythrocyte development
0.52	GO:0006873	cellular ion homeostasis
0.45	GO:0015672	monovalent inorganic cation transport
0.45	GO:0015695	organic cation transport
0.43	GO:0015840	urea transport
0.35	GO:0015701	bicarbonate transport
0.34	GO:0030001	metal ion transport

0.77	GO:0008519	ammonium transmembrane transporter activity
0.59	GO:0030506	ankyrin binding
0.58	GO:0022842	narrow pore channel activity
0.36	GO:0035379	carbon dioxide transmembrane transporter activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.44	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.34	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

0.33

GO:0016705

sp|Q3C2E2|CD20_CANLF
B-lymphocyte antigen CD20
Search

MS4A1

0.96	Membrane spanning 4-domains A1

0.44	GO:0023026	MHC class II protein complex binding
0.43	GO:0005154	epidermal growth factor receptor binding

0.73	GO:0009897	external side of plasma membrane
0.67	GO:0005887	integral component of plasma membrane
0.56	GO:0005634	nucleus
0.42	GO:0070062	extracellular exosome

sp|Q3LSL6|CXCR4_CANLF
C-X-C chemokine receptor type 4
Search

CXCR4

0.71	C-X-C motif chemokine receptor 4

0.81	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.69	GO:0006935	chemotaxis
0.52	GO:0019722	calcium-mediated signaling
0.51	GO:0001666	response to hypoxia
0.51	GO:0050920	regulation of chemotaxis
0.38	GO:0048714	positive regulation of oligodendrocyte differentiation
0.38	GO:0043217	myelin maintenance
0.37	GO:0016477	cell migration
0.37	GO:0007409	axonogenesis

0.82	GO:0004950	chemokine receptor activity
0.79	GO:0019955	cytokine binding
0.55	GO:0032027	myosin light chain binding
0.51	GO:0043130	ubiquitin binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0003779	actin binding
0.35	GO:0001618	virus receptor activity
0.35	GO:0015026	coreceptor activity
0.32	GO:0008144	drug binding

0.54	GO:0005770	late endosome
0.54	GO:0005769	early endosome
0.53	GO:0005764	lysosome
0.51	GO:0031252	cell leading edge
0.49	GO:0009986	cell surface
0.44	GO:0030054	cell junction
0.42	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.36	GO:0030426	growth cone
0.36	GO:0070062	extracellular exosome

sp|Q3YIX4|PEBP1_CANLF
Phosphatidylethanolamine-binding protein 1
Search

PEBP1

0.63	Phosphatidylethanolamine-binding protein 1

0.55	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:0060409	positive regulation of acetylcholine metabolic process
0.51	GO:0048240	sperm capacitation
0.49	GO:0051412	response to corticosterone
0.49	GO:0010243	response to organonitrogen compound
0.49	GO:0043950	positive regulation of cAMP-mediated signaling
0.48	GO:0051602	response to electrical stimulus
0.48	GO:0042755	eating behavior
0.48	GO:0002026	regulation of the force of heart contraction
0.48	GO:0014823	response to activity

0.70	GO:0019901	protein kinase binding
0.56	GO:0004867	serine-type endopeptidase inhibitor activity
0.53	GO:0008289	lipid binding
0.44	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005102	receptor binding
0.40	GO:0019210	kinase inhibitor activity
0.38	GO:0003723	RNA binding

0.49	GO:0043209	myelin sheath
0.47	GO:0043679	axon terminus
0.47	GO:0009986	cell surface
0.46	GO:0005791	rough endoplasmic reticulum
0.46	GO:0008021	synaptic vesicle
0.46	GO:0043025	neuronal cell body
0.46	GO:0045177	apical part of cell
0.45	GO:0005615	extracellular space
0.45	GO:0005741	mitochondrial outer membrane
0.43	GO:1903561	extracellular vesicle

sp|Q3ZKN1|CATK_CANLF
Cathepsin K
Search

CTSK

0.93	Cathepsin K (Pycnodysostosis)

0.61	GO:0006508	proteolysis
0.59	GO:0030574	collagen catabolic process
0.58	GO:1903146	regulation of autophagy of mitochondrion
0.57	GO:1903955	positive regulation of protein targeting to mitochondrion
0.53	GO:0044257	cellular protein catabolic process
0.43	GO:0060348	bone development
0.43	GO:0009612	response to mechanical stimulus
0.43	GO:0051216	cartilage development
0.40	GO:0001957	intramembranous ossification
0.40	GO:0045453	bone resorption

0.72	GO:0008234	cysteine-type peptidase activity
0.59	GO:0001968	fibronectin binding
0.58	GO:0043394	proteoglycan binding
0.56	GO:0005518	collagen binding
0.50	GO:0004175	endopeptidase activity
0.37	GO:0046983	protein dimerization activity
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0043236	laminin binding
0.35	GO:0003677	DNA binding
0.34	GO:0070273	phosphatidylinositol-4-phosphate binding

0.54	GO:0005615	extracellular space
0.50	GO:0005764	lysosome
0.49	GO:0005654	nucleoplasm
0.39	GO:0005667	transcription factor complex
0.36	GO:0031904	endosome lumen
0.35	GO:0005775	vacuolar lumen
0.30	GO:0016020	membrane

0.72

GO:0008234

tr|Q45FF7|Q45FF7_CANLF
Protease serine 25
Search

HTRA2

0.77	HtrA serine peptidase 2

0.63	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization
0.61	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.61	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.61	GO:0035458	cellular response to interferon-beta
0.61	GO:0006508	proteolysis
0.60	GO:0070207	protein homotrimerization
0.59	GO:0071300	cellular response to retinoic acid
0.59	GO:0007628	adult walking behavior
0.59	GO:1903955	positive regulation of protein targeting to mitochondrion
0.58	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage

0.69	GO:0004252	serine-type endopeptidase activity
0.52	GO:0042802	identical protein binding
0.38	GO:0005520	insulin-like growth factor binding
0.35	GO:0051082	unfolded protein binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.34	GO:0005507	copper ion binding

0.63	GO:1905370	serine-type endopeptidase complex
0.61	GO:0035631	CD40 receptor complex
0.55	GO:0005758	mitochondrial intermembrane space
0.53	GO:0009898	cytoplasmic side of plasma membrane
0.52	GO:0000785	chromatin
0.50	GO:0005856	cytoskeleton
0.50	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.35	GO:0005576	extracellular region
0.35	GO:0031966	mitochondrial membrane

0.69

GO:0004252

tr|Q45FN0|Q45FN0_CANLF
Prostaglandin F2-alpha receptor
Search

PTGFR

0.97	Ovarian prostaglandin F receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0071798	response to prostaglandin D
0.61	GO:0071379	cellular response to prostaglandin stimulus
0.61	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.60	GO:0032355	response to estradiol
0.59	GO:0032496	response to lipopolysaccharide
0.56	GO:0008284	positive regulation of cell proliferation
0.55	GO:0043066	negative regulation of apoptotic process
0.52	GO:0010628	positive regulation of gene expression
0.36	GO:0007567	parturition

0.85	GO:0004958	prostaglandin F receptor activity
0.54	GO:0004960	thromboxane receptor activity
0.53	GO:0004957	prostaglandin E receptor activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.49	GO:0005576	extracellular region
0.44	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

EC:1.2.1

GO:0016620

sp|Q45T69|B2CL2_CANLF
Bcl-2-like protein 2
Search

BCL2L2

0.95

BCL-WEL

0.76	GO:0006915	apoptotic process
0.74	GO:0042981	regulation of apoptotic process
0.64	GO:0038034	signal transduction in absence of ligand
0.63	GO:0060011	Sertoli cell proliferation
0.60	GO:0043069	negative regulation of programmed cell death
0.54	GO:0007166	cell surface receptor signaling pathway
0.51	GO:1902532	negative regulation of intracellular signal transduction
0.50	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
0.45	GO:0006974	cellular response to DNA damage stimulus
0.44	GO:0035556	intracellular signal transduction

0.63	GO:0097718	disordered domain specific binding
0.57	GO:0046982	protein heterodimerization activity
0.57	GO:0042802	identical protein binding
0.46	GO:0051400	BH domain binding
0.42	GO:0003723	RNA binding

0.65	GO:0097136	Bcl-2 family protein complex
0.50	GO:0005741	mitochondrial outer membrane
0.50	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.36	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

sp|Q49HH9|TS1R3_CANLF
Taste receptor type 1 member 3
Search

TAS1R3

0.97	Taste receptor type 1 member 3

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0050917	sensory perception of umami taste
0.58	GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste

0.71	GO:0004930	G-protein coupled receptor activity
0.58	GO:0033041	sweet taste receptor activity
0.36	GO:0046982	protein heterodimerization activity

0.60	GO:1903767	sweet taste receptor complex
0.55	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q49HI0|TS1R2_CANLF
Taste receptor type 1 member 2
Search

TAS1R2

0.95	Taste receptor type 1 member 2

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0050909	sensory perception of taste
0.54	GO:0032467	positive regulation of cytokinesis
0.50	GO:0050907	detection of chemical stimulus involved in sensory perception
0.35	GO:0055114	oxidation-reduction process
0.35	GO:0010133	proline catabolic process to glutamate

0.71	GO:0004930	G-protein coupled receptor activity
0.56	GO:0033041	sweet taste receptor activity
0.36	GO:0016491	oxidoreductase activity
0.35	GO:0005515	protein binding

0.58	GO:1903767	sweet taste receptor complex
0.53	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0016491

sp|Q49LX5|SSR1_CANLF
Somatostatin receptor type 1
Search

SSTR1

0.97	Somatostatin receptor type 1 subtype A

0.86	GO:0038169	somatostatin receptor signaling pathway
0.77	GO:0009755	hormone-mediated signaling pathway
0.56	GO:0007218	neuropeptide signaling pathway
0.54	GO:1990823	response to leukemia inhibitory factor
0.53	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.51	GO:0071345	cellular response to cytokine stimulus
0.51	GO:0007215	glutamate receptor signaling pathway
0.50	GO:0071392	cellular response to estradiol stimulus
0.49	GO:0008285	negative regulation of cell proliferation
0.45	GO:0071385	cellular response to glucocorticoid stimulus

0.86	GO:0004994	somatostatin receptor activity
0.53	GO:0042923	neuropeptide binding
0.45	GO:0030165	PDZ domain binding
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0017046	peptide hormone binding
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0004985	opioid receptor activity

0.48	GO:0043005	neuron projection
0.45	GO:0005886	plasma membrane
0.40	GO:0005829	cytosol
0.36	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

sp|Q49LX6|SSR2_CANLF
Somatostatin receptor type 2
Search

SSTR2

0.97	Somatostatin receptor type 2

0.85	GO:0038169	somatostatin receptor signaling pathway
0.76	GO:0009755	hormone-mediated signaling pathway
0.56	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.53	GO:0007218	neuropeptide signaling pathway
0.50	GO:0071385	cellular response to glucocorticoid stimulus
0.50	GO:0071392	cellular response to estradiol stimulus
0.47	GO:0008285	negative regulation of cell proliferation
0.39	GO:0030432	peristalsis
0.38	GO:0021549	cerebellum development
0.38	GO:0006937	regulation of muscle contraction

0.85	GO:0004994	somatostatin receptor activity
0.56	GO:0030165	PDZ domain binding
0.51	GO:0042923	neuropeptide binding
0.35	GO:0017046	peptide hormone binding
0.34	GO:0046982	protein heterodimerization activity

0.48	GO:0005829	cytosol
0.47	GO:0043005	neuron projection
0.43	GO:0005887	integral component of plasma membrane
0.35	GO:0098802	plasma membrane receptor complex

tr|Q49RC1|Q49RC1_CANLF
NADH-ubiquinone oxidoreductase chain 5
Search

ND5

0.48	NADH-ubiquinone oxidoreductase chain 5

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0030964	NADH dehydrogenase complex
0.34	GO:0098798	mitochondrial protein complex
0.33	GO:1990204	oxidoreductase complex
0.33	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

EC:1.6.5.3

GO:0008137

tr|Q49RC5|Q49RC5_CANLF
Cytochrome c oxidase subunit 3
Search

COX3

0.44	Cytochrome c oxidase subunit 3

0.76	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport
0.38	GO:0008535	respiratory chain complex IV assembly

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.37	GO:0045277	respiratory chain complex IV
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

tr|Q4JIV8|Q4JIV8_CANLF
Melanocortin-4 receptor
Search

MC4R

0.94	Melanocortin 4 receptor variant

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0045780	positive regulation of bone resorption
0.54	GO:0019933	cAMP-mediated signaling
0.48	GO:0030073	insulin secretion
0.47	GO:0007631	feeding behavior
0.46	GO:0032868	response to insulin
0.38	GO:2000821	regulation of grooming behavior
0.38	GO:2000252	negative regulation of feeding behavior
0.38	GO:0002024	diet induced thermogenesis
0.38	GO:0019222	regulation of metabolic process

0.84	GO:0004977	melanocortin receptor activity
0.57	GO:0042923	neuropeptide binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0017046	peptide hormone binding

0.55	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

tr|Q4L144|Q4L144_CANLF
Somatostatin receptor subtype 3
Search

SSTR3

0.94	Type-three somatostatin receptor subtype B

0.86	GO:0038169	somatostatin receptor signaling pathway
0.77	GO:0009755	hormone-mediated signaling pathway
0.50	GO:0090276	regulation of peptide hormone secretion
0.49	GO:0032467	positive regulation of cytokinesis
0.49	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.48	GO:0007268	chemical synaptic transmission
0.47	GO:0042593	glucose homeostasis
0.47	GO:0050708	regulation of protein secretion
0.45	GO:0007218	neuropeptide signaling pathway
0.45	GO:0071385	cellular response to glucocorticoid stimulus

0.86	GO:0004994	somatostatin receptor activity
0.52	GO:0042923	neuropeptide binding
0.50	GO:0005102	receptor binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0060170	ciliary membrane
0.55	GO:0097730	non-motile cilium
0.48	GO:0043005	neuron projection
0.44	GO:0005887	integral component of plasma membrane
0.36	GO:0005581	collagen trimer
0.34	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm

tr|Q4LAL8|Q4LAL8_CANLF
Chloride channel protein
Search

CLCN3

0.52	Chloride channel protein (Fragment)

0.76	GO:1902476	chloride transmembrane transport
0.56	GO:0045794	negative regulation of cell volume

0.77	GO:0005247	voltage-gated chloride channel activity
0.57	GO:0072320	volume-sensitive chloride channel activity
0.53	GO:0030165	PDZ domain binding
0.48	GO:0046982	protein heterodimerization activity

0.54	GO:0042581	specific granule
0.52	GO:0045335	phagocytic vesicle
0.51	GO:0005770	late endosome
0.51	GO:0005769	early endosome
0.51	GO:0008021	synaptic vesicle
0.51	GO:0009897	external side of plasma membrane
0.49	GO:0012506	vesicle membrane
0.47	GO:0005794	Golgi apparatus
0.39	GO:0005887	integral component of plasma membrane

sp|Q4LAL9|CATD_CANLF
Cathepsin D
Search

CTSD

0.84	Cathepsin D preproprotein (Predicted)

0.61	GO:0006508	proteolysis
0.42	GO:0006914	autophagy
0.40	GO:0030163	protein catabolic process
0.39	GO:0003406	retinal pigment epithelium development
0.38	GO:0009607	response to biotic stimulus
0.37	GO:0061061	muscle structure development
0.37	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.36	GO:0009605	response to external stimulus
0.36	GO:0007033	vacuole organization
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0042277	peptide binding
0.34	GO:0008234	cysteine-type peptidase activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0005515	protein binding

0.73	GO:0005764	lysosome
0.42	GO:0042470	melanosome
0.39	GO:0005615	extracellular space
0.37	GO:0045121	membrane raft
0.36	GO:0031012	extracellular matrix
0.36	GO:1903561	extracellular vesicle
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen

0.34

GO:0008234

tr|Q4PLA8|Q4PLA8_CANLF
Multidrug resistance protein 1
Search

0.52	Multi-drug resistance protein 1 transcript variant 2

0.58	GO:1903793	positive regulation of anion transport
0.55	GO:0045332	phospholipid translocation
0.55	GO:0099040	ceramide translocation
0.55	GO:0055085	transmembrane transport
0.55	GO:1901557	response to fenofibrate
0.54	GO:1903413	cellular response to bile acid
0.53	GO:0032782	bile acid secretion
0.53	GO:0061091	regulation of phospholipid translocation
0.52	GO:0032376	positive regulation of cholesterol transport
0.51	GO:2001225	regulation of chloride transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.62	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.55	GO:0099038	ceramide-translocating ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0090555	phosphatidylethanolamine-translocating ATPase activity
0.48	GO:0042910	xenobiotic transmembrane transporter activity
0.44	GO:0015238	drug transmembrane transporter activity

0.57	GO:0046581	intercellular canaliculus
0.56	GO:0016324	apical plasma membrane
0.48	GO:0005925	focal adhesion
0.46	GO:0009986	cell surface
0.45	GO:0015629	actin cytoskeleton
0.44	GO:0005654	nucleoplasm
0.44	GO:0031526	brush border membrane
0.43	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.39	GO:0098857	membrane microdomain

sp|Q4PPC4|SCN1B_CANLF
Sodium channel subunit beta-1
Search

SCN1B

0.96	Voltage-gated sodium channel beta 1 subunit splice variant B

0.72	GO:0006814	sodium ion transport
0.65	GO:0065009	regulation of molecular function
0.65	GO:0086012	membrane depolarization during cardiac muscle cell action potential
0.64	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.63	GO:0086019	cell-cell signaling involved in cardiac conduction
0.62	GO:0086002	cardiac muscle cell action potential involved in contraction
0.62	GO:0010765	positive regulation of sodium ion transport
0.62	GO:0086091	regulation of heart rate by cardiac conduction
0.61	GO:1902305	regulation of sodium ion transmembrane transport
0.59	GO:0021966	corticospinal neuron axon guidance

0.85	GO:0017080	sodium channel regulator activity
0.66	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential
0.54	GO:0008200	ion channel inhibitor activity
0.49	GO:0044325	ion channel binding
0.44	GO:0022832	voltage-gated channel activity
0.43	GO:0022839	ion gated channel activity
0.43	GO:0008381	mechanosensitive ion channel activity
0.38	GO:0070008	serine-type exopeptidase activity
0.37	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016758	transferase activity, transferring hexosyl groups

0.82	GO:0001518	voltage-gated sodium channel complex
0.57	GO:0033268	node of Ranvier
0.56	GO:0030315	T-tubule
0.55	GO:0014704	intercalated disc
0.49	GO:0030018	Z disc
0.36	GO:0043209	myelin sheath
0.35	GO:0043025	neuronal cell body
0.34	GO:0005576	extracellular region

0.38

GO:0070008

sp|Q4PRC2|DCE2_CANLF
Glutamate decarboxylase 2
Search

GAD2

0.54	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.46	GO:0042136	neurotransmitter biosynthetic process
0.42	GO:0035641	locomotory exploration behavior
0.41	GO:0035176	social behavior
0.39	GO:0042493	response to drug
0.38	GO:0016053	organic acid biosynthetic process
0.37	GO:0016054	organic acid catabolic process
0.37	GO:1901565	organonitrogen compound catabolic process
0.36	GO:1901566	organonitrogen compound biosynthetic process
0.36	GO:0007268	chemical synaptic transmission

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.43	GO:0016595	glutamate binding
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0047485	protein N-terminus binding
0.33	GO:0070003	threonine-type peptidase activity
0.32	GO:0004175	endopeptidase activity

0.54	GO:0030424	axon
0.52	GO:0045202	synapse
0.41	GO:0044306	neuron projection terminus
0.41	GO:0099501	exocytic vesicle membrane
0.40	GO:0031225	anchored component of membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005938	cell cortex
0.39	GO:0098590	plasma membrane region
0.39	GO:0005829	cytosol
0.39	GO:0030054	cell junction

0.68

EC:4.1.1

GO:0016831

sp|Q4TUC0|RTBDN_CANLF
Retbindin
Search

RTBDN

0.97	LOW QUALITY PROTEIN: retbindin

0.45

GO:0048741

skeletal muscle fiber development

0.64

GO:1902444

riboflavin binding

0.73	GO:0033165	interphotoreceptor matrix
0.55	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q4U3Q4|PPARG_CANLF
Peroxisome proliferator-activated receptor gamma
Search

PPARG

0.93	Peroxisome proliferator-activated receptor gamma

0.80	GO:0048511	rhythmic process
0.79	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0010742	macrophage derived foam cell differentiation
0.60	GO:0045713	low-density lipoprotein particle receptor biosynthetic process
0.59	GO:1905563	negative regulation of vascular endothelial cell proliferation
0.59	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.59	GO:0010887	negative regulation of cholesterol storage
0.59	GO:0060331	negative regulation of response to interferon-gamma
0.59	GO:0010871	negative regulation of receptor biosynthetic process

0.82	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.59	GO:0050692	DBD domain binding
0.59	GO:0050693	LBD domain binding
0.58	GO:0046965	retinoid X receptor binding
0.57	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.57	GO:0051393	alpha-actinin binding
0.56	GO:0043621	protein self-association

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.48	GO:0005737	cytoplasm
0.43	GO:0044446	intracellular organelle part
0.35	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

sp|Q4VSN4|DUSTY_CANLF
Dual serine/threonine and tyrosine protein kinase
Search

DSTYK

0.96	Dual serine/threonine and tyrosine protein kinase

0.62	GO:0006468	protein phosphorylation
0.61	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.57	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.57	GO:0044344	cellular response to fibroblast growth factor stimulus
0.54	GO:0033674	positive regulation of kinase activity
0.54	GO:0043066	negative regulation of apoptotic process
0.45	GO:0018212	peptidyl-tyrosine modification
0.44	GO:0048568	embryonic organ development
0.41	GO:0035556	intracellular signal transduction

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0016323	basolateral plasma membrane
0.58	GO:0016324	apical plasma membrane
0.44	GO:0030054	cell junction
0.43	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q4VUI0|RHBG_CANLF
Ammonium transporter Rh type B
Search

RHBG

0.91	Rhesus blood group-associated glycoprotein b

0.77	GO:0072488	ammonium transmembrane transport
0.66	GO:0070634	transepithelial ammonium transport
0.48	GO:0015695	organic cation transport
0.48	GO:0048878	chemical homeostasis
0.43	GO:0019725	cellular homeostasis
0.34	GO:0015837	amine transport
0.34	GO:0030855	epithelial cell differentiation

0.77	GO:0008519	ammonium transmembrane transporter activity
0.64	GO:0030506	ankyrin binding
0.45	GO:0042802	identical protein binding
0.35	GO:0051087	chaperone binding

0.62	GO:0016323	basolateral plasma membrane
0.59	GO:0014731	spectrin-associated cytoskeleton
0.53	GO:0046658	anchored component of plasma membrane
0.52	GO:0005887	integral component of plasma membrane
0.49	GO:0016324	apical plasma membrane
0.46	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0016327	apicolateral plasma membrane
0.34	GO:0070062	extracellular exosome

sp|Q4W1W1|HACD1_CANLF
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
Search

HACD1

0.70	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

0.69	GO:0006633	fatty acid biosynthetic process
0.52	GO:0035335	peptidyl-tyrosine dephosphorylation
0.51	GO:0000038	very long-chain fatty acid metabolic process
0.51	GO:0030148	sphingolipid biosynthetic process
0.42	GO:0071529	cementum mineralization
0.39	GO:0010811	positive regulation of cell-substrate adhesion
0.38	GO:0014902	myotube differentiation
0.38	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.38	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.37	GO:0034622	cellular macromolecular complex assembly

0.84	GO:0102158	very-long-chain 3-hydroxyacyl-CoA dehydratase activity
0.84	GO:0102343	3-hydroxy-arachidoyl-CoA dehydratase activity
0.84	GO:0102345	3-hydroxy-lignoceroyl-CoA dehydratase activity
0.84	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity
0.54	GO:0018812	3-hydroxyacyl-CoA dehydratase activity
0.52	GO:0004725	protein tyrosine phosphatase activity
0.42	GO:0080023	3R-hydroxyacyl-CoA dehydratase activity
0.41	GO:0046848	hydroxyapatite binding
0.41	GO:0019899	enzyme binding
0.35	GO:0004864	protein phosphatase inhibitor activity

0.71	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:4.2.1.134

GO:0102343

tr|Q4W6L5|Q4W6L5_CANLF
Tissue factor
Search

0.97	Coagulation factor III, tissue factor

0.82	GO:0007596	blood coagulation
0.80	GO:0002541	activation of plasma proteins involved in acute inflammatory response
0.77	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.72	GO:0001938	positive regulation of endothelial cell proliferation
0.72	GO:0051897	positive regulation of protein kinase B signaling
0.72	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.71	GO:0045766	positive regulation of angiogenesis
0.50	GO:0019221	cytokine-mediated signaling pathway
0.40	GO:0002543	activation of blood coagulation via clotting cascade
0.40	GO:0030335	positive regulation of cell migration

0.68	GO:0002020	protease binding
0.64	GO:0005543	phospholipid binding
0.57	GO:0004252	serine-type endopeptidase activity
0.51	GO:0004896	cytokine receptor activity

0.74	GO:1905286	serine-type peptidase complex
0.64	GO:0009986	cell surface
0.63	GO:0031012	extracellular matrix
0.63	GO:0005615	extracellular space
0.41	GO:0005886	plasma membrane
0.40	GO:1903561	extracellular vesicle
0.37	GO:0098552	side of membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.57

GO:0004252

sp|Q4ZHR9|GCYB1_CANLF
Guanylate cyclase soluble subunit beta-1
Search

GUCY1B3

0.95	Guanylate cyclase soluble subunit beta-1

0.81	GO:0006182	cGMP biosynthetic process
0.61	GO:0035556	intracellular signal transduction
0.56	GO:0099555	trans-synaptic signaling by nitric oxide, modulating synaptic transmission
0.41	GO:0071732	cellular response to nitric oxide
0.36	GO:0006171	cAMP biosynthetic process
0.35	GO:0008015	blood circulation

0.81	GO:0004383	guanylate cyclase activity
0.62	GO:0020037	heme binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.46	GO:0004016	adenylate cyclase activity
0.40	GO:0047805	cytidylate cyclase activity
0.38	GO:0051879	Hsp90 protein binding
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0046872	metal ion binding

0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.38	GO:0048786	presynaptic active zone

0.81	EC:4.6.1.2	GO:0004383
0.40	KEGG:R00574	GO:0047805

sp|Q4ZHS0|GCYA3_CANLF
Guanylate cyclase soluble subunit alpha-3
Search

GUCY1A3

0.97	Guanylate cyclase soluble subunit alpha-3

0.80	GO:0006182	cGMP biosynthetic process
0.63	GO:0052565	response to defense-related host nitric oxide production
0.62	GO:0060087	relaxation of vascular smooth muscle
0.61	GO:0035556	intracellular signal transduction
0.61	GO:0030828	positive regulation of cGMP biosynthetic process
0.57	GO:0008217	regulation of blood pressure
0.42	GO:0090594	inflammatory response to wounding
0.35	GO:0009635	response to herbicide
0.35	GO:0006171	cAMP biosynthetic process
0.35	GO:0014070	response to organic cyclic compound

0.81	GO:0004383	guanylate cyclase activity
0.60	GO:0020037	heme binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.47	GO:0004016	adenylate cyclase activity
0.37	GO:0047805	cytidylate cyclase activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0043168	anion binding
0.35	GO:0005515	protein binding
0.34	GO:0004872	receptor activity

0.62	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81	EC:4.6.1.2	GO:0004383
0.37	KEGG:R00574	GO:0047805

tr|Q50DZ8|Q50DZ8_CANLF
Serotonin 5HT2B receptor
Search

HTR2B

0.97	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

0.85	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.80	GO:0006939	smooth muscle contraction
0.79	GO:0042310	vasoconstriction
0.78	GO:0050795	regulation of behavior
0.74	GO:0007507	heart development
0.63	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.61	GO:0071502	cellular response to temperature stimulus
0.61	GO:0070528	protein kinase C signaling
0.61	GO:0007202	activation of phospholipase C activity
0.61	GO:0051000	positive regulation of nitric-oxide synthase activity

0.85	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.63	GO:0051378	serotonin binding
0.60	GO:0001965	G-protein alpha-subunit binding
0.53	GO:0005096	GTPase activator activity
0.43	GO:0008144	drug binding

0.65	GO:0005887	integral component of plasma membrane
0.50	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm
0.39	GO:0043005	neuron projection
0.38	GO:0045202	synapse
0.38	GO:0030054	cell junction
0.36	GO:0036477	somatodendritic compartment
0.36	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0044297	cell body

sp|Q50KA8|NDKB_CANLF
Nucleoside diphosphate kinase B
Search

0.46	Nucleoside diphosphate kinase B

0.78	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.48	GO:0050679	positive regulation of epithelial cell proliferation
0.48	GO:0042981	regulation of apoptotic process
0.46	GO:0007595	lactation
0.46	GO:0043388	positive regulation of DNA binding
0.44	GO:2000026	regulation of multicellular organismal development
0.42	GO:0045597	positive regulation of cell differentiation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.46	GO:0043024	ribosomal small subunit binding
0.42	GO:0042802	identical protein binding
0.41	GO:0004536	deoxyribonuclease activity
0.41	GO:0019215	intermediate filament binding
0.40	GO:0046872	metal ion binding

0.50	GO:0001726	ruffle
0.46	GO:0043209	myelin sheath
0.45	GO:0031256	leading edge membrane
0.44	GO:0031253	cell projection membrane
0.43	GO:0030027	lamellipodium
0.42	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005925	focal adhesion
0.40	GO:0005739	mitochondrion
0.39	GO:0070062	extracellular exosome

0.79

EC:2.7.4.6

GO:0004550

sp|Q50KA9|NDKA_CANLF
Nucleoside diphosphate kinase A
Search

0.46	Nucleoside diphosphate kinase A

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.49	GO:0042981	regulation of apoptotic process
0.48	GO:0050679	positive regulation of epithelial cell proliferation
0.46	GO:0007595	lactation
0.46	GO:0043388	positive regulation of DNA binding
0.44	GO:2000026	regulation of multicellular organismal development
0.42	GO:0045597	positive regulation of cell differentiation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0043024	ribosomal small subunit binding
0.42	GO:0042802	identical protein binding
0.41	GO:0004536	deoxyribonuclease activity
0.41	GO:0019215	intermediate filament binding
0.40	GO:0019001	guanyl nucleotide binding

0.50	GO:0001726	ruffle
0.46	GO:0043209	myelin sheath
0.45	GO:0031256	leading edge membrane
0.45	GO:0031253	cell projection membrane
0.43	GO:0030027	lamellipodium
0.42	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005925	focal adhesion
0.40	GO:0005739	mitochondrion
0.39	GO:0070062	extracellular exosome

0.79

EC:2.7.4.6

GO:0004550

sp|Q52MQ7|KTDAP_CANLF
Keratinocyte differentiation-associated protein
Search

KRTDAP

0.97	Keratinocyte differentiation-associated protein isoform 2

0.41

GO:0030154

cell differentiation

0.79	GO:0042599	lamellar body
0.66	GO:0005576	extracellular region

sp|Q52S86|PODXL_CANLF
Podocalyxin
Search

PODXL

0.97	Podocalyxin like

0.77	GO:0016477	cell migration
0.76	GO:0022407	regulation of cell-cell adhesion
0.63	GO:0007162	negative regulation of cell adhesion
0.56	GO:0007155	cell adhesion
0.53	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.49	GO:0030335	positive regulation of cell migration
0.49	GO:0032534	regulation of microvillus assembly
0.46	GO:0032835	glomerulus development
0.45	GO:0061318	renal filtration cell differentiation
0.45	GO:0035850	epithelial cell differentiation involved in kidney development

0.36

GO:0005515

protein binding

0.62	GO:0016324	apical plasma membrane
0.54	GO:0042995	cell projection
0.49	GO:0031252	cell leading edge
0.46	GO:0036057	slit diaphragm
0.46	GO:0070062	extracellular exosome
0.44	GO:0045121	membrane raft
0.43	GO:0005815	microtubule organizing center
0.43	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.35	GO:0044297	cell body

sp|Q53VB8|FRIL_CANLF
Ferritin light chain
Search

FTL

0.55	Ferritin light chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.57	GO:0051238	sequestering of metal ion
0.53	GO:0051651	maintenance of location in cell
0.35	GO:0010288	response to lead ion
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0055114	oxidation-reduction process

0.75	GO:0008199	ferric iron binding
0.38	GO:0042802	identical protein binding
0.36	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor

0.49	GO:0070288	ferritin complex
0.41	GO:0044754	autolysosome
0.37	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0005766	primary lysosome
0.35	GO:0005775	vacuolar lumen
0.35	GO:0030141	secretory granule
0.35	GO:0030139	endocytic vesicle
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.16.3

GO:0016724

sp|Q5CAZ6|B3GA2_CANLF
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2
Search

B3GAT2

0.77	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase

0.74	GO:0006486	protein glycosylation
0.51	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.51	GO:0030204	chondroitin sulfate metabolic process
0.41	GO:0005975	carbohydrate metabolic process
0.34	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.34	GO:0051216	cartilage development
0.34	GO:0030198	extracellular matrix organization

0.85	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.54	GO:0046872	metal ion binding
0.39	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.4.1.135

GO:0015018

sp|Q5CB03|B3GA1_CANLF
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1
Search

B3GAT1

0.77	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase

0.74	GO:0006486	protein glycosylation
0.49	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.49	GO:0030204	chondroitin sulfate metabolic process
0.40	GO:0005975	carbohydrate metabolic process
0.34	GO:0007005	mitochondrion organization

0.85	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.54	GO:0046872	metal ion binding
0.53	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
0.33	GO:0005515	protein binding

0.74	GO:0000139	Golgi membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0005576	extracellular region
0.35	GO:0005796	Golgi lumen
0.34	GO:0031305	integral component of mitochondrial inner membrane

0.85

EC:2.4.1.135

GO:0015018

sp|Q5D0K2|CCKAR_CANLF
Cholecystokinin receptor type A
Search

CCKAR

0.96	Cholecystokinin receptor type A

0.79	GO:0038188	cholecystokinin signaling pathway
0.57	GO:0001764	neuron migration
0.55	GO:0030900	forebrain development
0.54	GO:0007409	axonogenesis
0.47	GO:0007631	feeding behavior
0.47	GO:0007586	digestion
0.46	GO:0046883	regulation of hormone secretion
0.46	GO:1901652	response to peptide
0.44	GO:0032870	cellular response to hormone stimulus
0.37	GO:0007584	response to nutrient

0.79	GO:0004951	cholecystokinin receptor activity
0.69	GO:0015054	gastrin receptor activity
0.45	GO:0042277	peptide binding

0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0043195	terminal bouton
0.34	GO:0005764	lysosome
0.34	GO:0005768	endosome
0.34	GO:0005783	endoplasmic reticulum

sp|Q5DUB2|NK2R_CANLF
Substance-K receptor
Search

TACR2

0.97	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.65	GO:1902093	positive regulation of flagellated sperm motility
0.61	GO:0070472	regulation of uterine smooth muscle contraction
0.49	GO:0045987	positive regulation of smooth muscle contraction
0.43	GO:0007267	cell-cell signaling
0.42	GO:0033685	negative regulation of luteinizing hormone secretion
0.42	GO:0035106	operant conditioning
0.42	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission
0.42	GO:0014827	intestine smooth muscle contraction
0.41	GO:0043117	positive regulation of vascular permeability

0.86	GO:0004995	tachykinin receptor activity
0.35	GO:0050254	rhodopsin kinase activity
0.34	GO:0005515	protein binding

0.63	GO:0097225	sperm midpiece
0.59	GO:0061827	sperm head
0.56	GO:0005886	plasma membrane
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.36	GO:0031252	cell leading edge
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.7.11.14

GO:0050254

sp|Q5DUB3|NK1R_CANLF
Substance-P receptor
Search

TACR1

0.97	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.61	GO:1902093	positive regulation of flagellated sperm motility
0.55	GO:0070472	regulation of uterine smooth muscle contraction
0.53	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.53	GO:0048265	response to pain
0.48	GO:0045987	positive regulation of smooth muscle contraction
0.44	GO:0007268	chemical synaptic transmission
0.42	GO:0072347	response to anesthetic
0.41	GO:0043279	response to alkaloid
0.41	GO:0060359	response to ammonium ion

0.86	GO:0004995	tachykinin receptor activity
0.34	GO:0050254	rhodopsin kinase activity
0.33	GO:0005515	protein binding

0.59	GO:0097225	sperm midpiece
0.58	GO:0061827	sperm head
0.56	GO:0005886	plasma membrane
0.38	GO:0030425	dendrite
0.37	GO:0044297	cell body
0.37	GO:0009986	cell surface
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.11.14

GO:0050254

sp|Q5DWN0|GFI1_CANLF
Zinc finger protein Gfi-1
Search

GFI1

0.91	Growth factor independent 1 transcriptional repressor

0.82	GO:0051569	regulation of histone H3-K4 methylation
0.76	GO:0030097	hemopoiesis
0.75	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway
0.73	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity
0.68	GO:0034121	regulation of toll-like receptor signaling pathway
0.67	GO:0010977	negative regulation of neuron projection development
0.66	GO:0071222	cellular response to lipopolysaccharide
0.62	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0007422	peripheral nervous system development
0.47	GO:0034101	erythrocyte homeostasis

0.67	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0044212	transcription regulatory region DNA binding
0.49	GO:0001085	RNA polymerase II transcription factor binding

0.72	GO:0016363	nuclear matrix
0.65	GO:0017053	transcriptional repressor complex
0.63	GO:0016604	nuclear body
0.46	GO:0005667	transcription factor complex

sp|Q5ECR9|CCR5_CANLF
C-C chemokine receptor type 5
Search

CCR5

0.87	G-protein coupled chemokine receptor

0.84	GO:0070098	chemokine-mediated signaling pathway
0.80	GO:0006954	inflammatory response
0.74	GO:0006955	immune response
0.71	GO:0006935	chemotaxis
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.46	GO:0070723	response to cholesterol
0.46	GO:0090026	positive regulation of monocyte chemotaxis
0.46	GO:0001974	blood vessel remodeling
0.45	GO:0071222	cellular response to lipopolysaccharide

0.85	GO:0016493	C-C chemokine receptor activity
0.50	GO:0019957	C-C chemokine binding
0.42	GO:0003779	actin binding
0.41	GO:0031727	CCR2 chemokine receptor binding
0.35	GO:0104005	hijacked molecular function
0.34	GO:0015026	coreceptor activity
0.34	GO:0004435	phosphatidylinositol phospholipase C activity

0.47	GO:0009897	external side of plasma membrane
0.42	GO:0005768	endosome
0.33	GO:0005887	integral component of plasma membrane

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

sp|Q5F2N4|FUT10_CANLF
Alpha-(1,3)-fucosyltransferase 10
Search

FUT10

0.79	Fucosyltransferase 10

0.80	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.53	GO:0097150	neuronal stem cell population maintenance
0.53	GO:0021799	cerebral cortex radially oriented cell migration
0.35	GO:0042355	L-fucose catabolic process
0.35	GO:0009566	fertilization
0.35	GO:0042060	wound healing
0.35	GO:0030097	hemopoiesis
0.34	GO:0006605	protein targeting
0.34	GO:0006457	protein folding

0.84	GO:0046920	alpha-(1->3)-fucosyltransferase activity
0.33	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.80	GO:0032580	Golgi cisterna membrane
0.47	GO:0005783	endoplasmic reticulum
0.47	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.84

GO:0046920

sp|Q5FBR4|RARA_CANLF
Retinoic acid receptor alpha
Search

RARA

0.93	Retinoic acid receptor alpha

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0003417	growth plate cartilage development
0.57	GO:0055012	ventricular cardiac muscle cell differentiation
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0061037	negative regulation of cartilage development
0.56	GO:0003148	outflow tract septum morphogenesis
0.56	GO:0002068	glandular epithelial cell development

0.85	GO:0003708	retinoic acid receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.54	GO:0043422	protein kinase B binding
0.53	GO:0001972	retinoic acid binding
0.53	GO:0051393	alpha-actinin binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0051018	protein kinase A binding
0.51	GO:0031490	chromatin DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.47	GO:0015629	actin cytoskeleton
0.47	GO:0070013	intracellular organelle lumen
0.46	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.39	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

sp|Q5FZI9|URIC_CANLF
Uricase
Search

0.66

Uricase

0.77	GO:0019628	urate catabolic process
0.73	GO:0006144	purine nucleobase metabolic process
0.52	GO:0055114	oxidation-reduction process
0.41	GO:0007031	peroxisome organization
0.35	GO:0046113	nucleobase catabolic process
0.33	GO:0009877	nodulation

0.84

GO:0004846

urate oxidase activity

0.69	GO:0042579	microbody
0.43	GO:0005739	mitochondrion
0.34	GO:0043233	organelle lumen
0.33	GO:0045335	phagocytic vesicle
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.84

EC:1.7.3.3

GO:0004846

sp|Q5I2M8|TLR9_CANLF
Toll-like receptor 9
Search

TLR9

0.79	Pattern recognition receptor

0.86	GO:0034162	toll-like receptor 9 signaling pathway
0.82	GO:0050729	positive regulation of inflammatory response
0.82	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.81	GO:0050707	regulation of cytokine secretion
0.80	GO:0002237	response to molecule of bacterial origin
0.78	GO:0045087	innate immune response
0.53	GO:0034163	regulation of toll-like receptor 9 signaling pathway
0.52	GO:0032728	positive regulation of interferon-beta production
0.52	GO:0032741	positive regulation of interleukin-18 production
0.52	GO:0034123	positive regulation of toll-like receptor signaling pathway

0.69	GO:0004888	transmembrane signaling receptor activity
0.48	GO:0035197	siRNA binding
0.47	GO:0045322	unmethylated CpG binding
0.46	GO:0005149	interleukin-1 receptor binding
0.43	GO:0038187	pattern recognition receptor activity
0.43	GO:0003779	actin binding
0.42	GO:0042803	protein homodimerization activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity

0.53	GO:0032009	early phagosome
0.51	GO:0036019	endolysosome
0.45	GO:0005783	endoplasmic reticulum
0.42	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005615	extracellular space
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.40	GO:0016323	basolateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.35	GO:0005765	lysosomal membrane

0.35	EC:2.7.1.137	GO:0016303
0.35	KEGG:R03362	GO:0016303

sp|Q5IFP1|3BHS_CANLF
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
Search

0.50	3 beta-hydroxysteroid dehydrogenase isomerase VI

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0034754	cellular hormone metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.38	GO:0014070	response to organic cyclic compound
0.38	GO:0008211	glucocorticoid metabolic process
0.37	GO:0010288	response to lead ion
0.37	GO:0033327	Leydig cell differentiation
0.37	GO:0034698	response to gonadotropin
0.37	GO:0021766	hippocampus development

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.54	GO:0102294	cholesterol dehydrogenase activity
0.53	GO:0004769	steroid delta-isomerase activity
0.38	GO:0010181	FMN binding
0.36	GO:0005496	steroid binding
0.36	GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity
0.35	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.35	GO:0051287	NAD binding
0.35	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.33	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.45	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.43	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.39	GO:0097425	smooth endoplasmic reticulum part
0.36	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.1.1.145

GO:0003854

tr|Q5J2F2|Q5J2F2_CANLF
NKX2-5
Search

NKX2-5

0.96	Cardiac homeobox transcription factor

0.82	GO:1903779	regulation of cardiac conduction
0.79	GO:0060048	cardiac muscle contraction
0.75	GO:0007507	heart development
0.66	GO:0006357	regulation of transcription by RNA polymerase II
0.65	GO:0060037	pharyngeal system development
0.64	GO:0014855	striated muscle cell proliferation
0.64	GO:0048536	spleen development
0.64	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.63	GO:0014706	striated muscle tissue development
0.63	GO:0010832	negative regulation of myotube differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.58	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.57	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003682	chromatin binding
0.55	GO:0001104	RNA polymerase II transcription cofactor activity
0.54	GO:0003690	double-stranded DNA binding
0.53	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.55	GO:0005667	transcription factor complex
0.53	GO:0032993	protein-DNA complex
0.45	GO:0044446	intracellular organelle part
0.40	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q5J7U3|Q5J7U3_CANLF
Endothelin receptor type A
Search

EDNRA

0.97	Endothelin receptor type A

0.86	GO:0086100	endothelin receptor signaling pathway
0.85	GO:0048484	enteric nervous system development
0.85	GO:0042310	vasoconstriction
0.83	GO:0008217	regulation of blood pressure
0.60	GO:0014820	tonic smooth muscle contraction
0.58	GO:0001569	branching involved in blood vessel morphogenesis
0.58	GO:0007585	respiratory gaseous exchange
0.56	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.56	GO:0014032	neural crest cell development
0.55	GO:0015758	glucose transport

0.86	GO:0004962	endothelin receptor activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding
0.32	GO:0003735	structural constituent of ribosome

0.36	GO:0005886	plasma membrane
0.34	GO:0098857	membrane microdomain
0.34	GO:0031965	nuclear membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|Q5JZQ7|CLN8_CANLF
Protein CLN8
Search

CLN8

0.97	Ceroid-lipofuscinosis, neuronal 8 (Epilepsy, progressive with mental retardation)

0.51	GO:0051933	amino acid neurotransmitter reuptake
0.50	GO:0098712	L-glutamate import across plasma membrane
0.50	GO:0021523	somatic motor neuron differentiation
0.49	GO:0060052	neurofilament cytoskeleton organization
0.49	GO:0050884	neuromuscular process controlling posture
0.48	GO:0007628	adult walking behavior
0.48	GO:0050881	musculoskeletal movement
0.48	GO:0001306	age-dependent response to oxidative stress
0.48	GO:0035176	social behavior
0.48	GO:0045494	photoreceptor cell maintenance

0.46	GO:0098793	presynapse
0.43	GO:0005783	endoplasmic reticulum
0.40	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q5JZQ8|CLN6_CANLF
Ceroid-lipofuscinosis neuronal protein 6 homolog
Search

CLN6

0.68	Ceroid-lipofuscinosis neuronal protein 6

0.60	GO:0007042	lysosomal lumen acidification
0.60	GO:0031987	locomotion involved in locomotory behavior
0.58	GO:0001573	ganglioside metabolic process
0.56	GO:0008203	cholesterol metabolic process
0.54	GO:0045862	positive regulation of proteolysis
0.53	GO:0007601	visual perception
0.49	GO:0044265	cellular macromolecule catabolic process
0.48	GO:0030203	glycosaminoglycan metabolic process
0.37	GO:0007229	integrin-mediated signaling pathway
0.36	GO:0007155	cell adhesion

0.52	GO:0042803	protein homodimerization activity
0.35	GO:0005509	calcium ion binding
0.32	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0008305	integrin complex
0.35	GO:0005789	endoplasmic reticulum membrane

sp|Q5JZQ9|CLN5_CANLF
Ceroid-lipofuscinosis neuronal protein 5
Search

CLN5

0.97	Ceroid-lipofuscinosis neuronal protein 5

0.46	GO:1904426	positive regulation of GTP binding
0.45	GO:0007040	lysosome organization
0.43	GO:0042147	retrograde transport, endosome to Golgi
0.43	GO:0007035	vacuolar acidification
0.43	GO:0006465	signal peptide processing
0.42	GO:0007601	visual perception
0.41	GO:0007420	brain development
0.41	GO:0070085	glycosylation
0.40	GO:0022008	neurogenesis
0.36	GO:0071695	anatomical structure maturation

0.45	GO:0005537	mannose binding
0.35	GO:0005515	protein binding
0.34	GO:0016829	lyase activity

0.78	GO:0005764	lysosome
0.44	GO:0005775	vacuolar lumen
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0098852	lytic vacuole membrane
0.40	GO:0005829	cytosol
0.40	GO:0005794	Golgi apparatus
0.39	GO:0005783	endoplasmic reticulum
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.34

EC:4

GO:0016829

tr|Q5JZR0|Q5JZR0_CANLF
Palmitoyl-protein thioesterase 1
Search

PPT1

0.84	Palmitoyl-protein thioesterase

0.84	GO:0002084	protein depalmitoylation
0.57	GO:0032429	regulation of phospholipase A2 activity
0.56	GO:0007625	grooming behavior
0.55	GO:0007040	lysosome organization
0.54	GO:0008306	associative learning
0.54	GO:0008344	adult locomotory behavior
0.53	GO:0099643	signal release from synapse
0.53	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.52	GO:0007601	visual perception
0.50	GO:0006836	neurotransmitter transport

0.83	GO:0008474	palmitoyl-(protein) hydrolase activity
0.43	GO:0016290	palmitoyl-CoA hydrolase activity
0.34	GO:0005515	protein binding

0.54	GO:0005764	lysosome
0.53	GO:0030424	axon
0.53	GO:0098793	presynapse
0.52	GO:0043025	neuronal cell body
0.52	GO:0030425	dendrite
0.49	GO:0005615	extracellular space
0.42	GO:0070382	exocytic vesicle
0.41	GO:0045121	membrane raft
0.39	GO:0005794	Golgi apparatus
0.39	GO:0005829	cytosol

0.83

EC:3.1.2.22

GO:0008474

sp|Q5KSK8|CXCR3_CANLF
C-X-C chemokine receptor type 3
Search

CXCR3

0.96	LOW QUALITY PROTEIN: C-X-C chemokine receptor type 3

0.82	GO:0070098	chemokine-mediated signaling pathway
0.74	GO:0002685	regulation of leukocyte migration
0.72	GO:0006954	inflammatory response
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0006935	chemotaxis
0.47	GO:0071954	chemokine (C-C motif) ligand 11 production
0.45	GO:1900118	negative regulation of execution phase of apoptosis
0.45	GO:0002376	immune system process
0.45	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.44	GO:0050921	positive regulation of chemotaxis

0.83	GO:0004950	chemokine receptor activity
0.61	GO:0019956	chemokine binding
0.42	GO:0005044	scavenger receptor activity
0.34	GO:0015026	coreceptor activity
0.32	GO:0008188	neuropeptide receptor activity

0.53	GO:0009897	external side of plasma membrane
0.38	GO:0005887	integral component of plasma membrane
0.36	GO:0005884	actin filament
0.35	GO:0031965	nuclear membrane
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol

sp|Q5KSU9|EDNRA_CANLF
Endothelin-1 receptor
Search

EDNRA

0.97	Endothelin receptor type A

0.86	GO:0086100	endothelin receptor signaling pathway
0.85	GO:0048484	enteric nervous system development
0.85	GO:0042310	vasoconstriction
0.83	GO:0008217	regulation of blood pressure
0.61	GO:0014820	tonic smooth muscle contraction
0.59	GO:0001569	branching involved in blood vessel morphogenesis
0.59	GO:0007585	respiratory gaseous exchange
0.57	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.57	GO:0014032	neural crest cell development
0.56	GO:0015758	glucose transport

0.86	GO:0004962	endothelin receptor activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding
0.32	GO:0003735	structural constituent of ribosome

0.36	GO:0005886	plasma membrane
0.35	GO:0098857	membrane microdomain
0.34	GO:0031965	nuclear membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|Q5KSV9|CXL10_CANLF
C-X-C motif chemokine 10
Search

CXCL10

0.85	C-X-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.72	GO:0006952	defense response
0.71	GO:1901740	negative regulation of myoblast fusion
0.70	GO:0043950	positive regulation of cAMP-mediated signaling
0.69	GO:1901509	regulation of endothelial tube morphogenesis
0.69	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.68	GO:0030816	positive regulation of cAMP metabolic process
0.68	GO:0072678	T cell migration

0.84	GO:0008009	chemokine activity
0.72	GO:0048248	CXCR3 chemokine receptor binding
0.62	GO:0008201	heparin binding
0.37	GO:0008603	cAMP-dependent protein kinase regulator activity
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0005509	calcium ion binding

0.71	GO:0005615	extracellular space
0.63	GO:0009897	external side of plasma membrane
0.32	GO:0005622	intracellular

0.33

EC:3.1.3.16

GO:0004721

tr|Q5KU49|Q5KU49_CANLF
K-Cl cotransporter
Search

SLC12A4

0.96	Potassium-chloride cotransporter-1

0.77	GO:1902476	chloride transmembrane transport
0.69	GO:0071477	cellular hypotonic salinity response
0.46	GO:0007268	chemical synaptic transmission
0.44	GO:0071805	potassium ion transmembrane transport
0.35	GO:0006508	proteolysis
0.35	GO:0006884	cell volume homeostasis
0.34	GO:0034975	protein folding in endoplasmic reticulum
0.33	GO:0006629	lipid metabolic process
0.33	GO:0006879	cellular iron ion homeostasis

0.85	GO:0015379	potassium:chloride symporter activity
0.51	GO:0019901	protein kinase binding
0.47	GO:0022820	potassium ion symporter activity
0.37	GO:0008239	dipeptidyl-peptidase activity
0.37	GO:0016805	dipeptidase activity
0.37	GO:0008235	metalloexopeptidase activity
0.34	GO:0008374	O-acyltransferase activity
0.33	GO:0008199	ferric iron binding

0.54	GO:0005887	integral component of plasma membrane
0.37	GO:0005765	lysosomal membrane
0.34	GO:0072546	ER membrane protein complex

0.37

EC:3.4.13

GO:0016805

sp|Q5NDE9|PMGT2_CANLF
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
Search

POMGNT2

0.97	Glycosyltransferase-like domain-containing protein 2

0.58	GO:0035269	protein O-linked mannosylation
0.57	GO:0001764	neuron migration
0.35	GO:0048747	muscle fiber development
0.35	GO:0060041	retina development in camera-type eye
0.34	GO:0007420	brain development

0.61	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0005515	protein binding

0.51	GO:0005783	endoplasmic reticulum
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016757

sp|Q5NDL9|EOGT_CANLF
EGF domain-specific O-linked N-acetylglucosamine transferase
Search

EOGT

0.96	EGF domain-specific O-linked N-acetylglucosamine transferase

0.56

GO:0006493

protein O-linked glycosylation

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.44	GO:0140096	catalytic activity, acting on a protein

0.44	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.65

GO:0016757

sp|Q5PU49|KPCD_CANLF
Protein kinase C delta type
Search

PRKCD

0.97	Protein kinase C delta type

0.68	GO:0006915	apoptotic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.60	GO:2000753	positive regulation of glucosylceramide catabolic process
0.60	GO:2000755	positive regulation of sphingomyelin catabolic process
0.60	GO:1900163	positive regulation of phospholipid scramblase activity
0.59	GO:0023021	termination of signal transduction
0.59	GO:2000304	positive regulation of ceramide biosynthetic process
0.59	GO:0051490	negative regulation of filopodium assembly
0.58	GO:0032613	interleukin-10 production

0.82	GO:0004697	protein kinase C activity
0.57	GO:0043560	insulin receptor substrate binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0008047	enzyme activator activity
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.67	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0005634	nucleus
0.51	GO:0005911	cell-cell junction
0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0042582	azurophil granule

0.82

EC:2.7.11.13

GO:0004697

sp|Q5Q9Z2|VHL_CANLF
Von Hippel-Lindau disease tumor suppressor
Search

VHL

0.95	von Hippel-Lindau disease tumor suppressor

0.80	GO:1902072	negative regulation of hypoxia-inducible factor-1alpha signaling pathway
0.80	GO:0048877	homeostasis of number of retina cells
0.78	GO:0061073	ciliary body morphogenesis
0.77	GO:0070244	negative regulation of thymocyte apoptotic process
0.77	GO:0061072	iris morphogenesis
0.77	GO:0045602	negative regulation of endothelial cell differentiation
0.76	GO:0003310	pancreatic A cell differentiation
0.74	GO:0043534	blood vessel endothelial cell migration
0.74	GO:0048069	eye pigmentation
0.74	GO:0003309	type B pancreatic cell differentiation

0.66	GO:0032403	protein complex binding
0.63	GO:0061630	ubiquitin protein ligase activity
0.51	GO:0008134	transcription factor binding
0.51	GO:0019899	enzyme binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.37	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0004984	olfactory receptor activity
0.36	GO:0004930	G-protein coupled receptor activity
0.34	GO:0016874	ligase activity

0.74	GO:0031462	Cul2-RING ubiquitin ligase complex
0.68	GO:0030891	VCB complex
0.65	GO:0005929	cilium
0.63	GO:0005730	nucleolus
0.62	GO:0005654	nucleoplasm
0.44	GO:0031209	SCAR complex
0.43	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.37	GO:0005667	transcription factor complex
0.37	GO:0005783	endoplasmic reticulum

0.37

GO:0004674

sp|Q5QQ50|XYLT2_CANLF
Xylosyltransferase 2
Search

XYLT2

0.97	Xylosyltransferase II

0.69	GO:0006024	glycosaminoglycan biosynthetic process
0.60	GO:0030202	heparin metabolic process
0.59	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.59	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.49	GO:0044272	sulfur compound biosynthetic process
0.44	GO:0030204	chondroitin sulfate metabolic process
0.34	GO:0048701	embryonic cranial skeleton morphogenesis

0.86	GO:0030158	protein xylosyltransferase activity
0.77	GO:0008375	acetylglucosaminyltransferase activity

0.44	GO:0000139	Golgi membrane
0.40	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.86

EC:2.4.2.26

GO:0030158

sp|Q5QQ56|XYLT1_CANLF
Xylosyltransferase 1
Search

XYLT1

0.91	Xylosyltransferase I

0.68	GO:0006024	glycosaminoglycan biosynthetic process
0.49	GO:0030166	proteoglycan biosynthetic process
0.47	GO:0030201	heparan sulfate proteoglycan metabolic process
0.47	GO:0050654	chondroitin sulfate proteoglycan metabolic process
0.45	GO:1903510	mucopolysaccharide metabolic process
0.41	GO:0044272	sulfur compound biosynthetic process
0.40	GO:0048701	embryonic cranial skeleton morphogenesis
0.38	GO:0043436	oxoacid metabolic process
0.37	GO:0034605	cellular response to heat
0.36	GO:0048681	negative regulation of axon regeneration

0.85	GO:0030158	protein xylosyltransferase activity
0.75	GO:0008375	acetylglucosaminyltransferase activity

0.48	GO:0000139	Golgi membrane
0.40	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.2.26

GO:0030158

sp|Q5QQX7|CP19A_CANLF
Aromatase
Search

CYP19A1

0.81

Aromatase

0.62	GO:2000866	positive regulation of estradiol secretion
0.61	GO:0006710	androgen catabolic process
0.61	GO:0002677	negative regulation of chronic inflammatory response
0.61	GO:0010760	negative regulation of macrophage chemotaxis
0.60	GO:0061370	testosterone biosynthetic process
0.60	GO:0060736	prostate gland growth
0.59	GO:0030540	female genitalia development
0.59	GO:0060065	uterus development
0.57	GO:0008585	female gonad development
0.55	GO:0030879	mammary gland development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0019825	oxygen binding
0.33	GO:0009055	electron transfer activity

0.50	GO:0005783	endoplasmic reticulum
0.38	GO:0044297	cell body
0.38	GO:0043195	terminal bouton
0.37	GO:0030425	dendrite
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.35	GO:0044309	neuron spine
0.34	GO:0008021	synaptic vesicle
0.34	GO:0098794	postsynapse
0.33	GO:0005829	cytosol

0.68

GO:0016705

sp|Q5R1P0|NMDZ1_CANLF
Glutamate receptor ionotropic, NMDA 1
Search

GRIN1

0.95	Glutamate ionotropic receptor NMDA type subunit 1

0.79	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.58	GO:0018964	propylene metabolic process
0.57	GO:0021586	pons maturation
0.56	GO:1905429	response to glycine
0.56	GO:0001661	conditioned taste aversion
0.55	GO:0060134	prepulse inhibition
0.55	GO:0043278	response to morphine
0.55	GO:0008355	olfactory learning

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.76	GO:0004970	ionotropic glutamate receptor activity
0.57	GO:0016594	glycine binding
0.55	GO:0099094	ligand-gated cation channel activity
0.55	GO:0016595	glutamate binding
0.53	GO:0022843	voltage-gated cation channel activity
0.52	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.52	GO:0005262	calcium channel activity
0.51	GO:0005516	calmodulin binding
0.49	GO:0005102	receptor binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.58	GO:0017146	NMDA selective glutamate receptor complex
0.53	GO:0043197	dendritic spine
0.53	GO:0014069	postsynaptic density
0.53	GO:0008021	synaptic vesicle
0.49	GO:0009986	cell surface
0.47	GO:0005783	endoplasmic reticulum
0.41	GO:0044422	organelle part
0.38	GO:0043083	synaptic cleft

sp|Q5R1P3|NMDE2_CANLF
Glutamate receptor ionotropic, NMDA 2B
Search

GRIN2B

0.94	Glutamate ionotropic receptor NMDA type subunit 2B

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.59	GO:0045471	response to ethanol
0.59	GO:0060402	calcium ion transport into cytosol
0.59	GO:0019722	calcium-mediated signaling
0.42	GO:0051290	protein heterotetramerization
0.42	GO:0007611	learning or memory
0.42	GO:1900273	positive regulation of long-term synaptic potentiation
0.41	GO:0001964	startle response

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.60	GO:0016594	glycine binding
0.59	GO:0099604	ligand-gated calcium channel activity
0.55	GO:0022843	voltage-gated cation channel activity
0.42	GO:0016595	glutamate binding
0.37	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.37	GO:0031749	D2 dopamine receptor binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

0.77	GO:0098794	postsynapse
0.74	GO:0097060	synaptic membrane
0.70	GO:0030054	cell junction
0.63	GO:0017146	NMDA selective glutamate receptor complex
0.43	GO:0032279	asymmetric synapse
0.41	GO:0097458	neuron part
0.41	GO:0070382	exocytic vesicle
0.40	GO:0120025	plasma membrane bounded cell projection
0.40	GO:0009986	cell surface
0.36	GO:0043083	synaptic cleft

sp|Q5TJE1|DAXX_CANLF
Death domain-associated protein 6
Search

DAXX

0.89	Death domain-associated protein 6

0.88	GO:0072738	cellular response to diamide
0.87	GO:1903936	cellular response to sodium arsenite
0.86	GO:0071280	cellular response to copper ion
0.85	GO:0071276	cellular response to cadmium ion
0.85	GO:0030521	androgen receptor signaling pathway
0.84	GO:1901216	positive regulation of neuron death
0.83	GO:0034620	cellular response to unfolded protein
0.80	GO:0034605	cellular response to heat
0.80	GO:0031396	regulation of protein ubiquitination
0.77	GO:0032147	activation of protein kinase activity

0.85	GO:0050681	androgen receptor binding
0.85	GO:0032183	SUMO binding
0.83	GO:0047485	protein N-terminus binding
0.82	GO:0002039	p53 binding
0.80	GO:0030295	protein kinase activator activity
0.80	GO:0003714	transcription corepressor activity
0.79	GO:0003713	transcription coactivator activity
0.77	GO:0042393	histone binding
0.77	GO:0031625	ubiquitin protein ligase binding
0.76	GO:0019901	protein kinase binding

0.84	GO:0016605	PML body
0.76	GO:0000775	chromosome, centromeric region
0.73	GO:0070603	SWI/SNF superfamily-type complex
0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.44	GO:0000792	heterochromatin
0.41	GO:0001741	XY body
0.40	GO:0044297	cell body
0.39	GO:0043005	neuron projection
0.39	GO:0005938	cell cortex

sp|Q5TJE2|ZBT22_CANLF
Zinc finger and BTB domain-containing protein 22
Search

ZBTB22

0.45	Zinc finger and BTB domain containing 9

0.37	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.33	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.33	GO:0007018	microtubule-based movement

0.54	GO:0003677	DNA binding
0.36	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.33	GO:0003777	microtubule motor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q5TJE4|TPSN_CANLF
Tapasin
Search

TAPBP

0.93	TAP binding protein (Tapasin)

0.85

GO:0019885

antigen processing and presentation of endogenous peptide antigen via MHC class I

0.34

GO:0003676

nucleic acid binding

0.30

GO:0044425

membrane part

sp|Q5TJE5|RGL2_CANLF
Ral guanine nucleotide dissociation stimulator-like 2
Search

RGL2

0.90	Ral guanine nucleotide dissociation stimulator

0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.64	GO:0032485	regulation of Ral protein signal transduction
0.64	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.61	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.41	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.56	GO:0017048	Rho GTPase binding
0.37	GO:0030695	GTPase regulator activity
0.36	GO:0017160	Ral GTPase binding

0.45	GO:0005622	intracellular
0.38	GO:0005903	brush border
0.34	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q5TJE6|PFD6_CANLF
Prefoldin subunit 6
Search

PFDN6

0.93	HLA class II region expressed gene KE2

0.69	GO:0006457	protein folding
0.57	GO:0051131	chaperone-mediated protein complex assembly
0.34	GO:0007021	tubulin complex assembly
0.33	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.33	GO:0006470	protein dephosphorylation
0.32	GO:0006508	proteolysis

0.71	GO:0051082	unfolded protein binding
0.55	GO:0051087	chaperone binding
0.34	GO:0003723	RNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0015631	tubulin binding
0.33	GO:0004252	serine-type endopeptidase activity

0.80	GO:0016272	prefoldin complex
0.37	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus

0.33

GO:0004252

sp|Q5TJE7|WDR46_CANLF
WD repeat-containing protein 46
Search

WDR46

0.93	WD repeat-containing protein 46

0.78	GO:1903955	positive regulation of protein targeting to mitochondrion
0.63	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.41	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.40	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.40	GO:0000967	rRNA 5'-end processing
0.33	GO:0051638	barbed-end actin filament uncapping
0.33	GO:2000813	negative regulation of barbed-end actin filament capping
0.33	GO:1902745	positive regulation of lamellipodium organization
0.33	GO:0030335	positive regulation of cell migration
0.32	GO:0030001	metal ion transport

0.38	GO:0003723	RNA binding
0.32	GO:0046873	metal ion transmembrane transporter activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0016491	oxidoreductase activity

0.62	GO:0030686	90S preribosome
0.62	GO:0032040	small-subunit processome
0.58	GO:0005730	nucleolus
0.41	GO:0030688	preribosome, small subunit precursor
0.40	GO:0005581	collagen trimer
0.38	GO:0005654	nucleoplasm
0.37	GO:0005840	ribosome
0.33	GO:0030027	lamellipodium
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

sp|Q5TJE8|B3GT4_CANLF
Beta-1,3-galactosyltransferase 4
Search

B3GALT4

0.46	Hexosyltransferase

0.74	GO:0006486	protein glycosylation
0.68	GO:0001574	ganglioside biosynthetic process
0.36	GO:0035235	ionotropic glutamate receptor signaling pathway
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0034220	ion transmembrane transport
0.33	GO:0010467	gene expression
0.33	GO:0051307	meiotic chromosome separation
0.33	GO:0007194	negative regulation of adenylate cyclase activity
0.32	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0009086	methionine biosynthetic process

0.81	GO:0008378	galactosyltransferase activity
0.57	GO:0008194	UDP-glycosyltransferase activity
0.36	GO:0030594	neurotransmitter receptor activity
0.36	GO:0008066	glutamate receptor activity
0.36	GO:0005230	extracellular ligand-gated ion channel activity
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.33	GO:0008227	G-protein coupled amine receptor activity
0.33	GO:0047150	betaine-homocysteine S-methyltransferase activity
0.33	GO:0004197	cysteine-type endopeptidase activity

0.72	GO:0000139	Golgi membrane
0.34	GO:0005840	ribosome
0.33	GO:0072686	mitotic spindle
0.33	GO:0005813	centrosome
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:2.4.1	GO:0008378
0.33	KEGG:R02821	GO:0047150

sp|Q5TJE9|RS18_CANLF
40S ribosomal protein S18
Search

RPS18

0.43	Ribosomal protein S18

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.43	GO:0042254	ribosome biogenesis
0.41	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0043413	macromolecule glycosylation
0.34	GO:0009100	glycoprotein metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0008378	galactosyltransferase activity
0.33	GO:0046873	metal ion transmembrane transporter activity
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005840	ribosome
0.46	GO:0005829	cytosol
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.34

GO:0008378

sp|Q5TJF0|VPS52_CANLF
Vacuolar protein sorting-associated protein 52 homolog
Search

VPS52

0.93	VPS52, GARP complex subunit

0.84	GO:0007041	lysosomal transport
0.84	GO:0032456	endocytic recycling
0.74	GO:0048611	embryonic ectodermal digestive tract development
0.73	GO:0010668	ectodermal cell differentiation
0.61	GO:0006896	Golgi to vacuole transport
0.58	GO:0042147	retrograde transport, endosome to Golgi

0.83	GO:0019905	syntaxin binding
0.58	GO:0017137	Rab GTPase binding

0.85	GO:1990745	EARP complex
0.85	GO:0000938	GARP complex
0.76	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q5TJF3|RING1_CANLF
E3 ubiquitin-protein ligase RING1
Search

RING1

0.51	Ring finger protein 1

0.65	GO:0035518	histone H2A monoubiquitination
0.59	GO:0048593	camera-type eye morphogenesis
0.57	GO:0009952	anterior/posterior pattern specification
0.55	GO:0045892	negative regulation of transcription, DNA-templated
0.50	GO:0050790	regulation of catalytic activity
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0070317	negative regulation of G0 to G1 transition

0.58	GO:0097027	ubiquitin-protein transferase activator activity
0.55	GO:0003682	chromatin binding
0.50	GO:0016874	ligase activity
0.38	GO:0046872	metal ion binding
0.37	GO:0016740	transferase activity
0.35	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.85	GO:0035102	PRC1 complex
0.63	GO:0001739	sex chromatin
0.57	GO:0016604	nuclear body
0.53	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.50

GO:0016874

sp|Q5TJF5|DHB8_CANLF
Estradiol 17-beta-dehydrogenase 8
Search

HSD17B8

0.37	Beta-ketoacyl-ACP reductase

0.58	GO:0008210	estrogen metabolic process
0.57	GO:0051290	protein heterotetramerization
0.57	GO:0008209	androgen metabolic process
0.53	GO:0042446	hormone biosynthetic process
0.52	GO:0006694	steroid biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0006633	fatty acid biosynthetic process
0.35	GO:0030001	metal ion transport
0.35	GO:0046949	fatty-acyl-CoA biosynthetic process
0.34	GO:0055085	transmembrane transport

0.60	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.60	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity
0.60	GO:0070404	NADH binding
0.58	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.51	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.46	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.43	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.43	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.36	GO:0046873	metal ion transmembrane transporter activity
0.34	GO:0050034	L-rhamnose 1-dehydrogenase activity

0.51	GO:0005759	mitochondrial matrix
0.45	GO:0005740	mitochondrial envelope
0.42	GO:0005886	plasma membrane
0.36	GO:0035102	PRC1 complex
0.30	GO:0031224	intrinsic component of membrane

0.60	EC:1.1.1.239	GO:0047035
0.60	KEGG:R01836	GO:0047035

sp|Q5TJF6|S39A7_CANLF
Zinc transporter SLC39A7
Search

SLC39A7

0.57	Zinc transporter

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.44	GO:0006882	cellular zinc ion homeostasis
0.41	GO:0072511	divalent inorganic cation transport
0.33	GO:0055114	oxidation-reduction process

0.68	GO:0046873	metal ion transmembrane transporter activity
0.42	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.33	GO:0016491	oxidoreductase activity

0.42	GO:0005783	endoplasmic reticulum
0.42	GO:0005654	nucleoplasm
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005794	Golgi apparatus
0.33	GO:0031984	organelle subcompartment
0.33	GO:0035102	PRC1 complex
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016491

sp|Q5TJF7|RXRB_CANLF
Retinoic acid receptor RXR-beta
Search

RXRB

0.97	Retinoid X nuclear receptor beta

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0030522	intracellular receptor signaling pathway
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0060038	cardiac muscle cell proliferation

0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.37	GO:0042809	vitamin D receptor binding
0.37	GO:0035326	enhancer binding
0.36	GO:0003713	transcription coactivator activity
0.36	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.35	GO:0005581	collagen trimer
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0043235	receptor complex
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005667	transcription factor complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

tr|Q5TJG5|Q5TJG5_CANLF
MHC class II antigen DO alpha
Search

0.40	HLA class II histocompatibility antigen, DO alpha chain

0.80	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.67	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.64	GO:0045580	regulation of T cell differentiation
0.49	GO:0002587	negative regulation of antigen processing and presentation of peptide antigen via MHC class II
0.42	GO:0045621	positive regulation of lymphocyte differentiation
0.40	GO:0050870	positive regulation of T cell activation
0.36	GO:0034097	response to cytokine
0.35	GO:0006952	defense response
0.34	GO:0071385	cellular response to glucocorticoid stimulus

0.54	GO:0023026	MHC class II protein complex binding
0.43	GO:0042605	peptide antigen binding
0.36	GO:0032395	MHC class II receptor activity
0.34	GO:0046982	protein heterodimerization activity

0.75	GO:0042613	MHC class II protein complex
0.42	GO:0005764	lysosome
0.41	GO:0009897	external side of plasma membrane
0.35	GO:0005581	collagen trimer
0.34	GO:0098852	lytic vacuole membrane
0.34	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

sp|Q5TJG6|BRD2_CANLF
Bromodomain-containing protein 2
Search

BRD2

0.83	Bromodomain containing 2

0.77	GO:0006334	nucleosome assembly
0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0002574	thrombocyte differentiation
0.46	GO:0030917	midbrain-hindbrain boundary development
0.45	GO:0021510	spinal cord development
0.44	GO:0030902	hindbrain development
0.42	GO:0042981	regulation of apoptotic process

0.83	GO:0070577	lysine-acetylated histone binding
0.76	GO:0003682	chromatin binding

0.79	GO:0016607	nuclear speck
0.47	GO:0005737	cytoplasm

tr|Q5TJG8|Q5TJG8_CANLF
MHC class II antigen DM alpha
Search

HLA-DMA

0.65	Histocompatibility antigen DM heterodimer heavy chain

0.79	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.57	GO:0002399	MHC class II protein complex assembly
0.57	GO:0002501	peptide antigen assembly with MHC protein complex
0.38	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.36	GO:0002636	positive regulation of germinal center formation
0.36	GO:0045059	positive thymic T cell selection
0.35	GO:0002922	positive regulation of humoral immune response
0.35	GO:0045582	positive regulation of T cell differentiation
0.35	GO:0002449	lymphocyte mediated immunity

0.56	GO:0023026	MHC class II protein complex binding
0.36	GO:0032395	MHC class II receptor activity

0.75	GO:0042613	MHC class II protein complex
0.49	GO:0009986	cell surface
0.42	GO:0043227	membrane-bounded organelle
0.40	GO:0043229	intracellular organelle
0.37	GO:0043230	extracellular organelle
0.37	GO:0005581	collagen trimer
0.36	GO:0005615	extracellular space
0.36	GO:0098805	whole membrane
0.35	GO:0012505	endomembrane system
0.34	GO:0044422	organelle part

sp|Q5U820|CFTR_CANLF
Cystic fibrosis transmembrane conductance regulator
Search

CFTR

0.93	Cystic fibrosis transmembrane conductance regulator

0.76	GO:1902476	chloride transmembrane transport
0.71	GO:0035377	transepithelial water transport
0.70	GO:0060081	membrane hyperpolarization
0.69	GO:0045852	pH elevation
0.69	GO:1904321	response to forskolin
0.68	GO:0048240	sperm capacitation
0.68	GO:0015701	bicarbonate transport
0.67	GO:0071320	cellular response to cAMP
0.66	GO:0050891	multicellular organismal water homeostasis
0.65	GO:1901655	cellular response to ketone

0.86	GO:0005260	intracellularly ATP-gated chloride channel activity
0.68	GO:0019869	chloride channel inhibitor activity
0.68	GO:0015106	bicarbonate transmembrane transporter activity
0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0030165	PDZ domain binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0019899	enzyme binding

0.81	GO:0034707	chloride channel complex
0.64	GO:0016324	apical plasma membrane
0.64	GO:0055037	recycling endosome
0.62	GO:0005769	early endosome
0.57	GO:0005789	endoplasmic reticulum membrane
0.56	GO:0098588	bounding membrane of organelle
0.55	GO:0044440	endosomal part
0.54	GO:0005887	integral component of plasma membrane
0.53	GO:0005791	rough endoplasmic reticulum
0.52	GO:0098805	whole membrane

0.86

EC:3.6.3.49

GO:0005260

tr|Q5U9D0|Q5U9D0_CANLF
Sodium-glucose cotransporter-like 1
Search

SLC5A1

0.85	Low-affinity Na-dependent glucose cotransporter (Predicted)

0.57	GO:0015758	glucose transport
0.56	GO:1905950	monosaccharide transmembrane transport
0.48	GO:0006814	sodium ion transport
0.47	GO:0106001	intestinal hexose absorption
0.37	GO:0001656	metanephros development
0.35	GO:0098655	cation transmembrane transport
0.34	GO:0015992	proton transport
0.34	GO:0098660	inorganic ion transmembrane transport

0.62	GO:0005412	glucose:sodium symporter activity
0.35	GO:0005402	cation:sugar symporter activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.45	GO:0005887	integral component of plasma membrane
0.38	GO:0005903	brush border
0.37	GO:0016324	apical plasma membrane
0.36	GO:0031253	cell projection membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0005911	cell-cell junction

sp|Q5U9D2|HEPC_CANLF
Hepcidin
Search

HAMP

0.96	Hepcidin antimicrobial peptide

0.76	GO:0006879	cellular iron ion homeostasis
0.65	GO:1904479	negative regulation of intestinal absorption
0.64	GO:0060586	multicellular organismal iron ion homeostasis
0.61	GO:0010039	response to iron ion
0.56	GO:0034760	negative regulation of iron ion transmembrane transport
0.49	GO:0042742	defense response to bacterium
0.45	GO:0010469	regulation of receptor activity
0.43	GO:0050832	defense response to fungus
0.42	GO:1903413	cellular response to bile acid
0.41	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development

0.47	GO:0005179	hormone activity
0.39	GO:0097690	iron channel inhibitor activity
0.37	GO:0005507	copper ion binding

0.66	GO:0005576	extracellular region
0.40	GO:0045179	apical cortex
0.40	GO:0014704	intercalated disc
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q5UK76|ASIP_CANLF
Agouti-signaling protein
Search

ASIP

0.97	Agouti signaling protein transcript variant 1A

0.76	GO:0009755	hormone-mediated signaling pathway
0.43	GO:0048023	positive regulation of melanin biosynthetic process
0.43	GO:0040030	regulation of molecular function, epigenetic
0.42	GO:0032438	melanosome organization
0.42	GO:0008343	adult feeding behavior
0.42	GO:0032402	melanosome transport
0.42	GO:0071514	genetic imprinting
0.41	GO:0042438	melanin biosynthetic process
0.36	GO:0006091	generation of precursor metabolites and energy

0.70

GO:0005102

receptor binding

0.66	GO:0005576	extracellular region
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q5VK71|AKAP8_CANLF
A-kinase anchor protein 8
Search

AKAP8

0.96	A-kinase anchoring protein 8

0.67	GO:0033127	regulation of histone phosphorylation
0.66	GO:0071380	cellular response to prostaglandin E stimulus
0.66	GO:0031065	positive regulation of histone deacetylation
0.65	GO:0032720	negative regulation of tumor necrosis factor production
0.64	GO:0044839	cell cycle G2/M phase transition
0.62	GO:0071222	cellular response to lipopolysaccharide
0.62	GO:0007076	mitotic chromosome condensation
0.47	GO:0016310	phosphorylation
0.41	GO:0045087	innate immune response
0.38	GO:0015031	protein transport

0.66	GO:0034237	protein kinase A regulatory subunit binding
0.66	GO:0051059	NF-kappaB binding
0.63	GO:0042826	histone deacetylase binding
0.55	GO:0003677	DNA binding
0.53	GO:0017151	DEAD/H-box RNA helicase binding
0.49	GO:0016301	kinase activity
0.37	GO:0008270	zinc ion binding
0.35	GO:0003682	chromatin binding
0.35	GO:0003723	RNA binding
0.35	GO:0005521	lamin binding

0.67	GO:0001939	female pronucleus
0.65	GO:0016363	nuclear matrix
0.58	GO:0000793	condensed chromosome
0.54	GO:0005654	nucleoplasm
0.40	GO:0005730	nucleolus
0.39	GO:0005794	Golgi apparatus
0.37	GO:0005739	mitochondrion
0.36	GO:0000785	chromatin
0.35	GO:0044454	nuclear chromosome part
0.33	GO:0030529	intracellular ribonucleoprotein complex

tr|Q5W412|Q5W412_CANLF
Proteasome subunit beta type
Search

PSMB9

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.67	GO:0002376	immune system process
0.54	GO:2000116	regulation of cysteine-type endopeptidase activity
0.45	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0071347	cellular response to interleukin-1
0.36	GO:1901423	response to benzene
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0071257	cellular response to electrical stimulus
0.35	GO:0014889	muscle atrophy

0.77	GO:0004298	threonine-type endopeptidase activity
0.35	GO:0045296	cadherin binding
0.35	GO:0070628	proteasome binding

0.76	GO:0005839	proteasome core complex
0.59	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.44	GO:1990111	spermatoproteasome complex
0.36	GO:0070062	extracellular exosome
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part

0.77

EC:3.4.25

GO:0004298

sp|Q5W416|PSB8_CANLF
Proteasome subunit beta type-8
Search

PSMB8

0.53	Proteasome subunit beta type

0.71	GO:0051603	proteolysis involved in cellular protein catabolic process
0.53	GO:0045444	fat cell differentiation
0.49	GO:0019882	antigen processing and presentation
0.49	GO:0052548	regulation of endopeptidase activity
0.36	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0060337	type I interferon signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway

0.77	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.75	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.56	GO:1990111	spermatoproteasome complex
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

tr|Q5W418|Q5W418_CANLF
MHC class II DO beta
Search

0.61	Patr class II histocompatibility antigen, DO beta chain

0.80	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.52	GO:0002587	negative regulation of antigen processing and presentation of peptide antigen via MHC class II
0.42	GO:0048002	antigen processing and presentation of peptide antigen
0.41	GO:0019883	antigen processing and presentation of endogenous antigen
0.38	GO:0019884	antigen processing and presentation of exogenous antigen
0.37	GO:0042886	amide transport
0.36	GO:0071702	organic substance transport
0.36	GO:0002377	immunoglobulin production
0.36	GO:0002449	lymphocyte mediated immunity

0.58	GO:0023026	MHC class II protein complex binding
0.41	GO:0042287	MHC protein binding
0.41	GO:0015440	peptide-transporting ATPase activity
0.36	GO:0042605	peptide antigen binding
0.36	GO:0032395	MHC class II receptor activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0042613	MHC class II protein complex
0.52	GO:0005764	lysosome
0.41	GO:0042825	TAP complex
0.38	GO:0005768	endosome
0.37	GO:0098852	lytic vacuole membrane
0.36	GO:0044433	cytoplasmic vesicle part
0.36	GO:0009897	external side of plasma membrane
0.34	GO:0005794	Golgi apparatus
0.34	GO:0016607	nuclear speck

0.41

EC:3.6.3.43

GO:0015440

sp|Q5W7P8|TRBM_CANLF
Thrombomodulin
Search

THBD

0.96	Thrombomodulin

0.82	GO:0030195	negative regulation of blood coagulation
0.64	GO:0007565	female pregnancy
0.60	GO:0007165	signal transduction
0.47	GO:0010165	response to X-ray
0.47	GO:0007596	blood coagulation
0.46	GO:0051591	response to cAMP
0.45	GO:0032496	response to lipopolysaccharide
0.39	GO:0051918	negative regulation of fibrinolysis
0.39	GO:0010543	regulation of platelet activation
0.38	GO:0050866	negative regulation of cell activation

0.70	GO:0005509	calcium ion binding
0.69	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0005515	protein binding
0.34	GO:0005201	extracellular matrix structural constituent
0.33	GO:0001871	pattern binding
0.32	GO:0030246	carbohydrate binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0005887	integral component of plasma membrane
0.59	GO:0009986	cell surface
0.47	GO:0016327	apicolateral plasma membrane
0.43	GO:0005774	vacuolar membrane
0.43	GO:0005615	extracellular space
0.33	GO:0005578	proteinaceous extracellular matrix

sp|Q5WR07|TNFB_CANLF
Lymphotoxin-alpha
Search

LTA

0.89	Tumor necrosis factor alpha

0.74	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.73	GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus
0.72	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin
0.70	GO:0048535	lymph node development
0.70	GO:0044130	negative regulation of growth of symbiont in host
0.68	GO:0032729	positive regulation of interferon-gamma production
0.66	GO:0050830	defense response to Gram-positive bacterium
0.45	GO:0060252	positive regulation of glial cell proliferation
0.44	GO:0048147	negative regulation of fibroblast proliferation

0.83	GO:0005164	tumor necrosis factor receptor binding
0.79	GO:0005125	cytokine activity

0.72	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.33	GO:1903561	extracellular vesicle
0.33	GO:0009986	cell surface
0.33	GO:0098552	side of membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|Q5WR08|Q5WR08_CANLF
NFKBIL1
Search

NFKBIL1

0.97	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

0.86	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.85	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.84	GO:0032720	negative regulation of tumor necrosis factor production
0.84	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.83	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.81	GO:0071222	cellular response to lipopolysaccharide
0.41	GO:0042994	cytoplasmic sequestering of transcription factor
0.40	GO:0006915	apoptotic process
0.39	GO:0010469	regulation of receptor activity
0.39	GO:0006955	immune response

0.40	GO:0005164	tumor necrosis factor receptor binding
0.40	GO:0005125	cytokine activity
0.38	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0046872	metal ion binding

0.65	GO:0005829	cytosol
0.60	GO:0005634	nucleus
0.38	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.38

GO:0004674

sp|Q5WR09|VATG1_CANLF
V-type proton ATPase subunit G 1
Search

ATP6V1G2

0.68	V-type proton ATPase subunit G

0.62	GO:0015992	proton transport
0.55	GO:0055085	transmembrane transport
0.47	GO:0036295	cellular response to increased oxygen levels
0.44	GO:0006879	cellular iron ion homeostasis
0.37	GO:0090383	phagosome acidification
0.37	GO:0033572	transferrin transport
0.36	GO:0008286	insulin receptor signaling pathway
0.36	GO:0016241	regulation of macroautophagy

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.48	GO:0022853	active ion transmembrane transporter activity
0.47	GO:0051117	ATPase binding
0.46	GO:0015078	hydrogen ion transmembrane transporter activity

0.82	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.54	GO:0030285	integral component of synaptic vesicle membrane
0.44	GO:0005765	lysosomal membrane
0.42	GO:0005829	cytosol
0.41	GO:0042470	melanosome
0.39	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome

sp|Q5WR10|DX39B_CANLF
Spliceosome RNA helicase DDX39B
Search

DDX39B

0.86	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

0.78	GO:0046784	viral mRNA export from host cell nucleus
0.77	GO:2000002	negative regulation of DNA damage checkpoint
0.73	GO:0010501	RNA secondary structure unwinding
0.71	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.70	GO:0000245	spliceosomal complex assembly
0.69	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.68	GO:0051028	mRNA transport
0.67	GO:0006405	RNA export from nucleus
0.43	GO:0006974	cellular response to DNA damage stimulus

0.78	GO:0043008	ATP-dependent protein binding
0.76	GO:0030621	U4 snRNA binding
0.73	GO:0017070	U6 snRNA binding
0.69	GO:0004004	ATP-dependent RNA helicase activity
0.64	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005687	U4 snRNP
0.72	GO:0000346	transcription export complex
0.71	GO:0005688	U6 snRNP
0.69	GO:0016607	nuclear speck
0.68	GO:0005681	spliceosomal complex
0.46	GO:0005730	nucleolus
0.45	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q5WR11|Q5WR11_CANLF
MHC class I antigen
Search

0.41	Classical MHC class I antigen

0.75	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.68	GO:0006955	immune response

0.41	GO:0042605	peptide antigen binding
0.38	GO:0005102	receptor binding

0.74	GO:0042612	MHC class I protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q5XFN2|DESM_CANLF
Desmin
Search

DES

0.97	Muscle-specific intermediate filament desmin (Predicted)

0.58	GO:0045109	intermediate filament organization
0.47	GO:0006936	muscle contraction
0.47	GO:0007517	muscle organ development
0.46	GO:0007626	locomotory behavior
0.44	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.43	GO:0045214	sarcomere organization
0.43	GO:0060047	heart contraction
0.42	GO:0014706	striated muscle tissue development
0.36	GO:0045107	intermediate filament polymerization
0.36	GO:0033275	actin-myosin filament sliding

0.62	GO:0005198	structural molecule activity
0.50	GO:0042802	identical protein binding
0.49	GO:0008092	cytoskeletal protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0005882	intermediate filament
0.59	GO:0030018	Z disc
0.58	GO:0005916	fascia adherens
0.58	GO:0097512	cardiac myofibril
0.56	GO:0042383	sarcolemma
0.56	GO:0031594	neuromuscular junction
0.45	GO:0005634	nucleus
0.44	GO:0097433	dense body
0.36	GO:0070062	extracellular exosome
0.35	GO:0005921	gap junction

0.33

GO:0004674

sp|Q5XM32|RXFP2_CANLF
Relaxin receptor 2
Search

RXFP2

0.91	Leucine-rich repeat-containing G protein-coupled receptor 8

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0008584	male gonad development
0.55	GO:0019933	cAMP-mediated signaling
0.47	GO:0060427	lung connective tissue development
0.46	GO:0007567	parturition
0.45	GO:0060658	nipple morphogenesis
0.43	GO:0030198	extracellular matrix organization
0.43	GO:0030154	cell differentiation
0.40	GO:0043950	positive regulation of cAMP-mediated signaling
0.39	GO:0071695	anatomical structure maturation

0.72	GO:0004930	G-protein coupled receptor activity
0.57	GO:0016500	protein-hormone receptor activity
0.46	GO:0042562	hormone binding
0.38	GO:0042277	peptide binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.40	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q5XNR9|LIFR_CANLF
Leukemia inhibitory factor receptor
Search

LIFR

0.95	Leukemia inhibitory factor receptor alpha

0.79	GO:0019221	cytokine-mediated signaling pathway
0.54	GO:0048861	leukemia inhibitory factor signaling pathway
0.48	GO:0008284	positive regulation of cell proliferation
0.38	GO:0010656	negative regulation of muscle cell apoptotic process
0.38	GO:0031100	animal organ regeneration
0.37	GO:0048812	neuron projection morphogenesis
0.37	GO:0001959	regulation of cytokine-mediated signaling pathway
0.37	GO:0014070	response to organic cyclic compound

0.80	GO:0004896	cytokine receptor activity
0.54	GO:0005127	ciliary neurotrophic factor receptor binding
0.50	GO:0019838	growth factor binding
0.38	GO:0019955	cytokine binding
0.36	GO:0046982	protein heterodimerization activity

0.48	GO:0043235	receptor complex
0.45	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q5XNS0|TBX19_CANLF
T-box transcription factor TBX19
Search

TBX19

0.97	T-box-containing protein TBXT (Fragment)

0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding

0.61

GO:0005634

nucleus

sp|Q5XWD5|IF_CANLF
Gastric intrinsic factor
Search

GIF

0.97	Gastric intrinsic factor

0.78	GO:0015889	cobalamin transport
0.44	GO:0006824	cobalt ion transport
0.39	GO:0043043	peptide biosynthetic process
0.38	GO:0009235	cobalamin metabolic process
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0010467	gene expression
0.37	GO:0009059	macromolecule biosynthetic process

0.75	GO:0031419	cobalamin binding
0.40	GO:0003735	structural constituent of ribosome
0.36	GO:0019843	rRNA binding

0.70	GO:0005902	microvillus
0.67	GO:0016324	apical plasma membrane
0.63	GO:0005768	endosome
0.61	GO:0005615	extracellular space
0.39	GO:0005840	ribosome
0.39	GO:0043202	lysosomal lumen

tr|Q5XX73|Q5XX73_CANLF
Purinergic receptor P2Y1 variant 1
Search

P2RY1

0.97	Purinergic receptor P2Y, G-protein coupled 1

0.85	GO:0090075	relaxation of muscle
0.85	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.83	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.81	GO:0030168	platelet activation
0.57	GO:0043270	positive regulation of ion transport
0.55	GO:0071407	cellular response to organic cyclic compound
0.45	GO:0097746	regulation of blood vessel diameter
0.44	GO:0051047	positive regulation of secretion
0.43	GO:0070255	regulation of mucus secretion
0.43	GO:0051240	positive regulation of multicellular organismal process

0.85	GO:0001608	G-protein coupled nucleotide receptor activity
0.83	GO:0001614	purinergic nucleotide receptor activity
0.43	GO:0045031	ATP-activated adenosine receptor activity
0.43	GO:0045032	ADP-activated adenosine receptor activity
0.42	GO:0031686	A1 adenosine receptor binding
0.40	GO:0097110	scaffold protein binding
0.38	GO:0043531	ADP binding
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0045125	bioactive lipid receptor activity
0.35	GO:0005524	ATP binding

0.44	GO:0005886	plasma membrane
0.40	GO:0014069	postsynaptic density
0.39	GO:0030425	dendrite
0.39	GO:0044297	cell body
0.39	GO:0045177	apical part of cell
0.36	GO:0009986	cell surface
0.36	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|Q5XXR2|MCH_CANLF
Pro-MCH
Search

PMCH

0.97	Pro-melanin concentrating hormone

0.78	GO:0007268	chemical synaptic transmission
0.76	GO:0010469	regulation of receptor activity
0.62	GO:0007631	feeding behavior
0.41	GO:0007218	neuropeptide signaling pathway
0.37	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep
0.37	GO:0032227	negative regulation of synaptic transmission, dopaminergic
0.36	GO:0007595	lactation
0.36	GO:0045776	negative regulation of blood pressure
0.36	GO:0048168	regulation of neuronal synaptic plasticity
0.36	GO:0002027	regulation of heart rate

0.87	GO:0030354	melanin-concentrating hormone activity
0.38	GO:0031777	type 1 melanin-concentrating hormone receptor binding

0.49	GO:0005634	nucleus
0.40	GO:0005576	extracellular region
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q60F97|5HT2C_CANLF
5-hydroxytryptamine receptor 2C
Search

HTR2C

0.97	5-hydroxytryptamine (Serotonin) receptor 2C long isoform

0.78	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.77	GO:0007631	feeding behavior
0.75	GO:0007626	locomotory behavior
0.63	GO:0043397	regulation of corticotropin-releasing hormone secretion
0.62	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.60	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.60	GO:0001662	behavioral fear response
0.59	GO:0032098	regulation of appetite
0.59	GO:0051209	release of sequestered calcium ion into cytosol
0.59	GO:0031644	regulation of neurological system process

0.78	GO:0099589	serotonin receptor activity
0.75	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.75	GO:0008227	G-protein coupled amine receptor activity
0.63	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
0.61	GO:0051378	serotonin binding
0.33	GO:0005515	protein binding

0.62	GO:0005887	integral component of plasma membrane
0.37	GO:0009897	external side of plasma membrane
0.34	GO:0043198	dendritic shaft
0.32	GO:0005622	intracellular

sp|Q60FC1|ANGP1_CANLF
Angiopoietin-1
Search

ANGPT1

0.91	Angiopoietin-1

0.85	GO:0048014	Tie signaling pathway
0.79	GO:0001525	angiogenesis
0.61	GO:2000446	regulation of macrophage migration inhibitory factor signaling pathway
0.60	GO:0030210	heparin biosynthetic process
0.60	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.59	GO:0043116	negative regulation of vascular permeability
0.59	GO:0002740	negative regulation of cytokine secretion involved in immune response
0.59	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.59	GO:0043535	regulation of blood vessel endothelial cell migration
0.58	GO:0002092	positive regulation of receptor internalization

0.85	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0005172	vascular endothelial growth factor receptor binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.57	GO:0005902	microvillus
0.54	GO:0098857	membrane microdomain
0.52	GO:0005615	extracellular space
0.42	GO:0005886	plasma membrane
0.37	GO:1903561	extracellular vesicle
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q64H34|CCR3_CANLF
C-C chemokine receptor type 3
Search

CCR3

0.97	C-C motif chemokine receptor 3

0.83	GO:0070098	chemokine-mediated signaling pathway
0.79	GO:0006954	inflammatory response
0.70	GO:0006935	chemotaxis
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0006955	immune response
0.64	GO:0090026	positive regulation of monocyte chemotaxis
0.56	GO:0051094	positive regulation of developmental process
0.56	GO:0051240	positive regulation of multicellular organismal process
0.55	GO:2000026	regulation of multicellular organismal development
0.53	GO:0001938	positive regulation of endothelial cell proliferation

0.85	GO:0016493	C-C chemokine receptor activity
0.66	GO:0019957	C-C chemokine binding
0.48	GO:0004435	phosphatidylinositol phospholipase C activity
0.38	GO:0003779	actin binding
0.37	GO:0031727	CCR2 chemokine receptor binding

0.51	GO:0009897	external side of plasma membrane
0.40	GO:0005768	endosome
0.36	GO:0043025	neuronal cell body
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005615	extracellular space

0.48	EC:3.1.4.11	GO:0004435
0.48	KEGG:R03435	GO:0004435

sp|Q64H35|CCL26_CANLF
C-C motif chemokine 26
Search

0.65	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.69	GO:0097529	myeloid leukocyte migration
0.68	GO:0010469	regulation of receptor activity
0.63	GO:0072676	lymphocyte migration
0.63	GO:0071674	mononuclear cell migration
0.60	GO:0001938	positive regulation of endothelial cell proliferation
0.60	GO:0070098	chemokine-mediated signaling pathway
0.58	GO:0043547	positive regulation of GTPase activity
0.58	GO:0032103	positive regulation of response to external stimulus

0.84	GO:0008009	chemokine activity
0.66	GO:0048020	CCR chemokine receptor binding
0.44	GO:0005153	interleukin-8 receptor binding
0.40	GO:0031737	CX3C chemokine receptor binding
0.38	GO:0005178	integrin binding
0.36	GO:0030276	clathrin binding
0.36	GO:0016004	phospholipase activator activity
0.35	GO:0035091	phosphatidylinositol binding
0.35	GO:0003779	actin binding
0.34	GO:0046983	protein dimerization activity

0.66	GO:0005576	extracellular region
0.37	GO:0009986	cell surface
0.36	GO:0030136	clathrin-coated vesicle
0.30	GO:0016020	membrane

sp|Q64HP0|CCND1_CANLF
G1/S-specific cyclin-D1
Search

CCND1

0.97	G1/S-specific cyclin-D1

0.67	GO:0007049	cell cycle
0.58	GO:0070141	response to UV-A
0.56	GO:0044783	G1 DNA damage checkpoint
0.56	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.56	GO:0071157	negative regulation of cell cycle arrest
0.56	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.56	GO:1902807	negative regulation of cell cycle G1/S phase transition
0.56	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.55	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.55	GO:0097421	liver regeneration

0.55	GO:0070064	proline-rich region binding
0.53	GO:0003714	transcription corepressor activity
0.53	GO:0042826	histone deacetylase binding
0.51	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.51	GO:0019901	protein kinase binding
0.48	GO:0008134	transcription factor binding
0.44	GO:0004672	protein kinase activity
0.38	GO:0032403	protein complex binding
0.35	GO:0060089	molecular transducer activity

0.61	GO:0005634	nucleus
0.56	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.53	GO:0017053	transcriptional repressor complex
0.51	GO:0005923	bicellular tight junction
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.35	GO:0005694	chromosome
0.35	GO:0012505	endomembrane system
0.34	GO:0031090	organelle membrane

0.51

EC:2.7.1

GO:0016538

sp|Q659K0|CCNB3_CANLF
G2/mitotic-specific cyclin-B3
Search

CCNB3

0.64	G2/mitotic-specific cyclin-B3

0.82	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.81	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.35	GO:0051301	cell division
0.35	GO:0051321	meiotic cell cycle
0.33	GO:0006397	mRNA processing

0.78

GO:0019901

protein kinase binding

0.60	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q659L1|FUT9_CANLF
Alpha-(1,3)-fucosyltransferase 9
Search

FUT9

0.74	Fucosyltransferase 9

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.38	GO:0007399	nervous system development
0.35	GO:0042355	L-fucose catabolic process

0.81

GO:0008417

fucosyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

sp|Q659X0|FUT8_CANLF
Alpha-(1,6)-fucosyltransferase
Search

FUT8

0.90	Alpha-(1,6)-fucosyltransferase

0.85	GO:0033578	protein glycosylation in Golgi
0.85	GO:0036071	N-glycan fucosylation
0.57	GO:0018279	protein N-linked glycosylation via asparagine
0.55	GO:0046368	GDP-L-fucose metabolic process
0.55	GO:0007585	respiratory gaseous exchange
0.54	GO:1900407	regulation of cellular response to oxidative stress
0.53	GO:0006491	N-glycan processing
0.53	GO:0007179	transforming growth factor beta receptor signaling pathway
0.52	GO:0043112	receptor metabolic process
0.51	GO:0007229	integrin-mediated signaling pathway

0.85	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity
0.42	GO:0017124	SH3 domain binding

0.77	GO:0032580	Golgi cisterna membrane
0.48	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.85	EC:2.4.1.68	GO:0008424
0.85	KEGG:R05988	GO:0008424

sp|Q689D1|TLR2_CANLF
Toll-like receptor 2
Search

TLR2

0.87	Pattern recognition receptor

0.86	GO:0034134	toll-like receptor 2 signaling pathway
0.84	GO:0050729	positive regulation of inflammatory response
0.84	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.82	GO:0050707	regulation of cytokine secretion
0.82	GO:0002237	response to molecule of bacterial origin
0.80	GO:0006954	inflammatory response
0.79	GO:0045087	innate immune response
0.57	GO:0071216	cellular response to biotic stimulus
0.57	GO:0002374	cytokine secretion involved in immune response
0.56	GO:0032613	interleukin-10 production

0.58	GO:0042497	triacyl lipopeptide binding
0.55	GO:0035325	Toll-like receptor binding
0.54	GO:0038187	pattern recognition receptor activity
0.52	GO:0001530	lipopolysaccharide binding
0.50	GO:0042834	peptidoglycan binding
0.49	GO:0032403	protein complex binding
0.48	GO:0046982	protein heterodimerization activity
0.45	GO:0038023	signaling receptor activity
0.39	GO:0042498	diacyl lipopeptide binding
0.38	GO:0070891	lipoteichoic acid binding

0.57	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex
0.56	GO:0098857	membrane microdomain
0.51	GO:0005794	Golgi apparatus
0.50	GO:0030670	phagocytic vesicle membrane
0.49	GO:0009986	cell surface
0.47	GO:0031226	intrinsic component of plasma membrane
0.39	GO:0106003	amyloid-beta complex
0.39	GO:0044297	cell body
0.39	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex
0.37	GO:0042995	cell projection

sp|Q68A91|CCL28_CANLF
C-C motif chemokine 28
Search

CCL28

0.68	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.77	GO:1903237	negative regulation of leukocyte tethering or rolling
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.73	GO:0001954	positive regulation of cell-matrix adhesion
0.68	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.47	GO:0007584	response to nutrient
0.41	GO:0031640	killing of cells of other organism
0.39	GO:0043207	response to external biotic stimulus
0.38	GO:0019835	cytolysis

0.84

GO:0008009

chemokine activity

0.72	GO:0005615	extracellular space
0.45	GO:1903561	extracellular vesicle
0.38	GO:0030141	secretory granule

sp|Q68A92|CCL3_CANLF
C-C motif chemokine 3
Search

0.76	C-C motif chemokine

0.81	GO:0060326	cell chemotaxis
0.74	GO:0010469	regulation of receptor activity
0.73	GO:0006955	immune response
0.62	GO:0097529	myeloid leukocyte migration
0.61	GO:0043615	astrocyte cell migration
0.60	GO:0071674	mononuclear cell migration
0.60	GO:0072676	lymphocyte migration
0.59	GO:0050718	positive regulation of interleukin-1 beta secretion
0.58	GO:0043525	positive regulation of neuron apoptotic process
0.58	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.83	GO:0008009	chemokine activity
0.58	GO:0004698	calcium-dependent protein kinase C activity
0.57	GO:0048020	CCR chemokine receptor binding
0.56	GO:0016004	phospholipase activator activity
0.55	GO:0042056	chemoattractant activity
0.39	GO:0042802	identical protein binding
0.35	GO:0008201	heparin binding
0.34	GO:0003735	structural constituent of ribosome

0.71	GO:0005615	extracellular space
0.46	GO:0005829	cytosol
0.34	GO:0015934	large ribosomal subunit
0.30	GO:0016020	membrane

0.58

GO:0004698

sp|Q68A93|CCL25_CANLF
C-C motif chemokine 25
Search

CCL25

0.97	C-C motif chemokine ligand 25

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.65	GO:1903237	negative regulation of leukocyte tethering or rolling
0.62	GO:0001954	positive regulation of cell-matrix adhesion
0.60	GO:0071674	mononuclear cell migration
0.60	GO:0072676	lymphocyte migration
0.59	GO:1990266	neutrophil migration
0.59	GO:0071347	cellular response to interleukin-1
0.58	GO:0071356	cellular response to tumor necrosis factor
0.58	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0008009	chemokine activity
0.68	GO:0048020	CCR chemokine receptor binding
0.39	GO:0005179	hormone activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q68AM8|SOCS3_CANLF
Suppressor of cytokine signaling 3
Search

SOCS3

0.97	Suppressor of cytokine signaling 3

0.85	GO:0007259	JAK-STAT cascade
0.78	GO:0043066	negative regulation of apoptotic process
0.68	GO:0016567	protein ubiquitination
0.64	GO:0060708	spongiotrophoblast differentiation
0.64	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.64	GO:0046627	negative regulation of insulin receptor signaling pathway
0.63	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.63	GO:0060707	trophoblast giant cell differentiation
0.62	GO:0060674	placenta blood vessel development
0.61	GO:0050728	negative regulation of inflammatory response

0.62	GO:0001784	phosphotyrosine residue binding
0.49	GO:0004860	protein kinase inhibitor activity
0.36	GO:0008269	JAK pathway signal transduction adaptor activity
0.36	GO:0005159	insulin-like growth factor receptor binding

0.45

GO:0005622

intracellular

sp|Q68AY9|CCL8_CANLF
C-C motif chemokine 8
Search

0.74	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.64	GO:0097529	myeloid leukocyte migration
0.60	GO:0071674	mononuclear cell migration
0.59	GO:0071347	cellular response to interleukin-1
0.58	GO:2000501	regulation of natural killer cell chemotaxis
0.58	GO:0071356	cellular response to tumor necrosis factor
0.57	GO:0006954	inflammatory response
0.56	GO:0019221	cytokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.61	GO:0048020	CCR chemokine receptor binding
0.52	GO:0016004	phospholipase activator activity
0.42	GO:0004672	protein kinase activity
0.42	GO:0008201	heparin binding
0.40	GO:0046983	protein dimerization activity
0.33	GO:0005153	interleukin-8 receptor binding

0.71	GO:0005615	extracellular space
0.36	GO:0005622	intracellular

sp|Q68AZ0|CCL4_CANLF
C-C motif chemokine 4
Search

CCL4

0.74	C-C motif chemokine

0.80	GO:0060326	cell chemotaxis
0.73	GO:0006955	immune response
0.71	GO:0010469	regulation of receptor activity
0.55	GO:0006954	inflammatory response
0.54	GO:0071674	mononuclear cell migration
0.54	GO:0097529	myeloid leukocyte migration
0.54	GO:0070098	chemokine-mediated signaling pathway
0.53	GO:0072676	lymphocyte migration
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:0071347	cellular response to interleukin-1

0.82	GO:0008009	chemokine activity
0.57	GO:0048020	CCR chemokine receptor binding
0.47	GO:0004698	calcium-dependent protein kinase C activity
0.47	GO:0016004	phospholipase activator activity
0.46	GO:0042056	chemoattractant activity
0.40	GO:0042802	identical protein binding
0.35	GO:0046817	chemokine receptor antagonist activity
0.34	GO:0030298	receptor signaling protein tyrosine kinase activator activity
0.34	GO:0008201	heparin binding
0.34	GO:0043621	protein self-association

0.70	GO:0005615	extracellular space
0.40	GO:0005829	cytosol
0.33	GO:0015934	large ribosomal subunit
0.30	GO:0016020	membrane

0.47	EC:2.7.11	GO:0004698
0.34	KEGG:R03435	GO:0004435

sp|Q68CI2|DOPO_CANLF
Dopamine beta-hydroxylase
Search

DBH

0.97	Dopamine beta-hydroxylase

0.62	GO:0042420	dopamine catabolic process
0.62	GO:0042421	norepinephrine biosynthetic process
0.61	GO:0042309	homoiothermy
0.59	GO:0042711	maternal behavior
0.58	GO:0001975	response to amphetamine
0.58	GO:0045907	positive regulation of vasoconstriction
0.58	GO:0048265	response to pain
0.57	GO:0001974	blood vessel remodeling
0.57	GO:0042596	fear response
0.57	GO:0048149	behavioral response to ethanol

0.84	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.72	GO:0005507	copper ion binding
0.41	GO:0031418	L-ascorbic acid binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding
0.32	GO:0003677	DNA binding

0.59	GO:0034774	secretory granule lumen
0.59	GO:0030667	secretory granule membrane
0.53	GO:0005615	extracellular space
0.52	GO:0005815	microtubule organizing center
0.49	GO:0005783	endoplasmic reticulum
0.44	GO:0042583	chromaffin granule
0.41	GO:0030658	transport vesicle membrane
0.36	GO:0043005	neuron projection
0.35	GO:0043025	neuronal cell body
0.35	GO:0045177	apical part of cell

0.84

EC:1.14.17

GO:0016715

sp|Q68Y86|CCL24_CANLF
C-C motif chemokine 24
Search

CCL24

0.63	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.76	GO:2000418	positive regulation of eosinophil migration
0.76	GO:0072677	eosinophil migration
0.74	GO:0006955	immune response
0.73	GO:0001938	positive regulation of endothelial cell proliferation
0.69	GO:0050729	positive regulation of inflammatory response
0.69	GO:0045766	positive regulation of angiogenesis
0.68	GO:0030838	positive regulation of actin filament polymerization
0.66	GO:0043547	positive regulation of GTPase activity
0.65	GO:0010469	regulation of receptor activity

0.84	GO:0008009	chemokine activity
0.79	GO:0031728	CCR3 chemokine receptor binding
0.37	GO:0031732	CCR7 chemokine receptor binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q68Y87|Q68Y87_CANLF
Cutaneous T cell attracting chemokine
Search

CCL27

0.97	C-C motif chemokine ligand 27

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.45	GO:0010820	positive regulation of T cell chemotaxis
0.44	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.44	GO:0071677	positive regulation of mononuclear cell migration
0.43	GO:0010469	regulation of receptor activity
0.39	GO:0031640	killing of cells of other organism
0.38	GO:0007267	cell-cell signaling
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0043207	response to external biotic stimulus

0.84	GO:0008009	chemokine activity
0.77	GO:0031728	CCR3 chemokine receptor binding

0.66	GO:0005576	extracellular region
0.38	GO:0005634	nucleus

sp|Q68Y88|CCL13_CANLF
C-C motif chemokine 13
Search

0.75	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.68	GO:0097529	myeloid leukocyte migration
0.61	GO:0071674	mononuclear cell migration
0.60	GO:0071347	cellular response to interleukin-1
0.59	GO:0071356	cellular response to tumor necrosis factor
0.59	GO:0006954	inflammatory response
0.58	GO:0019221	cytokine-mediated signaling pathway
0.57	GO:0072676	lymphocyte migration

0.84	GO:0008009	chemokine activity
0.63	GO:0048020	CCR chemokine receptor binding
0.47	GO:0016004	phospholipase activator activity
0.41	GO:0046983	protein dimerization activity
0.40	GO:0031737	CX3C chemokine receptor binding
0.40	GO:0004672	protein kinase activity
0.39	GO:0008201	heparin binding
0.39	GO:0005153	interleukin-8 receptor binding
0.38	GO:0005178	integrin binding

0.70	GO:0005615	extracellular space
0.37	GO:0009986	cell surface
0.36	GO:0005622	intracellular
0.33	GO:0098794	postsynapse
0.32	GO:0042995	cell projection
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q697L1|TRPV1_CANLF
Transient receptor potential cation channel subfamily V member 1
Search

TRPV1

0.95	Transient receptor potential vanilloid 1

0.62	GO:1901594	response to capsazepine
0.60	GO:0034220	ion transmembrane transport
0.60	GO:0050960	detection of temperature stimulus involved in thermoception
0.60	GO:0050968	detection of chemical stimulus involved in sensory perception of pain
0.59	GO:0060083	smooth muscle contraction involved in micturition
0.59	GO:0002024	diet induced thermogenesis
0.58	GO:1902656	calcium ion import into cytosol
0.58	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.58	GO:0071468	cellular response to acidic pH
0.58	GO:0001660	fever generation

0.70	GO:0005216	ion channel activity
0.56	GO:0051219	phosphoprotein binding
0.54	GO:0015085	calcium ion transmembrane transporter activity
0.52	GO:0022834	ligand-gated channel activity
0.41	GO:0005516	calmodulin binding
0.40	GO:0035091	phosphatidylinositol binding
0.40	GO:0017081	chloride channel regulator activity
0.39	GO:0004888	transmembrane signaling receptor activity
0.37	GO:0042802	identical protein binding
0.36	GO:0030554	adenyl nucleotide binding

0.53	GO:0043005	neuron projection
0.44	GO:0005886	plasma membrane
0.41	GO:0031252	cell leading edge
0.41	GO:0036477	somatodendritic compartment
0.41	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.39	GO:0044297	cell body
0.38	GO:0009986	cell surface
0.37	GO:0098552	side of membrane

sp|Q6A548|TERT_CANLF
Telomerase reverse transcriptase
Search

TERT

0.68	Telomerase reverse transcriptase

0.70	GO:0006278	RNA-dependent DNA biosynthetic process
0.67	GO:0010833	telomere maintenance via telomere lengthening
0.67	GO:1903704	negative regulation of production of siRNA involved in RNA interference
0.65	GO:1904751	positive regulation of protein localization to nucleolus
0.64	GO:0070200	establishment of protein localization to telomere
0.63	GO:2000773	negative regulation of cellular senescence
0.63	GO:0051000	positive regulation of nitric-oxide synthase activity
0.63	GO:0090399	replicative senescence
0.63	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.62	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.85	GO:0003721	telomerase RNA reverse transcriptase activity
0.67	GO:0070034	telomerase RNA binding
0.67	GO:0098680	template-free RNA nucleotidyltransferase
0.63	GO:0001223	transcription coactivator binding
0.61	GO:0047485	protein N-terminus binding
0.59	GO:0008022	protein C-terminus binding
0.56	GO:0051087	chaperone binding
0.55	GO:0042803	protein homodimerization activity
0.55	GO:0003677	DNA binding
0.53	GO:0003968	RNA-directed 5'-3' RNA polymerase activity

0.69	GO:0000333	telomerase catalytic core complex
0.66	GO:1990572	TERT-RMRP complex
0.63	GO:0016605	PML body
0.60	GO:0000781	chromosome, telomeric region
0.59	GO:0042645	mitochondrial nucleoid
0.58	GO:0016607	nuclear speck
0.56	GO:0005730	nucleolus
0.54	GO:0044454	nuclear chromosome part
0.51	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane

0.53

EC:2.7.7.48

GO:0003968

sp|Q6AW47|EST5A_CANLF
Carboxylesterase 5A
Search

CES5A

0.51	Carboxylesterase 5A

0.64

GO:0052689

carboxylic ester hydrolase activity

0.61	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.64	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.64	KEGG:R00630	GO:0052689

sp|Q6DYE7|RENI_CANLF
Renin
Search

REN

0.97

Renin

0.61	GO:0006508	proteolysis
0.60	GO:0002002	regulation of angiotensin levels in blood
0.59	GO:0002018	renin-angiotensin regulation of aldosterone production
0.58	GO:0042756	drinking behavior
0.55	GO:0001823	mesonephros development
0.54	GO:0008584	male gonad development
0.53	GO:0042445	hormone metabolic process
0.53	GO:0048469	cell maturation
0.52	GO:0051604	protein maturation
0.52	GO:0043408	regulation of MAPK cascade

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.49	GO:0005102	receptor binding
0.35	GO:0070492	oligosaccharide binding
0.35	GO:0097718	disordered domain specific binding
0.33	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0045177	apical part of cell
0.50	GO:0005615	extracellular space
0.37	GO:0005622	intracellular
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.33

EC:2.4.1.119

GO:0004579

sp|Q6EE22|UNK_CANLF
RING finger protein unkempt homolog
Search

UNK

0.92	RING finger protein unkempt

0.68	GO:2000766	negative regulation of cytoplasmic translation
0.64	GO:0001764	neuron migration
0.61	GO:0048667	cell morphogenesis involved in neuron differentiation

0.71	GO:1990715	mRNA CDS binding
0.54	GO:0046872	metal ion binding

0.63	GO:0005844	polysome
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q6EIY9|K2C1_CANLF
Keratin, type II cytoskeletal 1
Search

0.91	Keratin, type II cytoskeletal 2 epidermal

0.55	GO:0043588	skin development
0.53	GO:0018149	peptide cross-linking
0.51	GO:0033561	regulation of water loss via skin
0.51	GO:0001867	complement activation, lectin pathway
0.50	GO:0050728	negative regulation of inflammatory response
0.48	GO:0045104	intermediate filament cytoskeleton organization
0.47	GO:0008544	epidermis development
0.45	GO:0032980	keratinocyte activation
0.45	GO:0060429	epithelium development
0.44	GO:0051546	keratinocyte migration

0.62	GO:0005198	structural molecule activity
0.45	GO:0097110	scaffold protein binding
0.44	GO:0030246	carbohydrate binding
0.39	GO:0008092	cytoskeletal protein binding
0.36	GO:1990254	keratin filament binding
0.34	GO:0019899	enzyme binding
0.33	GO:0004872	receptor activity

0.83	GO:0045095	keratin filament
0.54	GO:0001533	cornified envelope
0.40	GO:0070062	extracellular exosome
0.38	GO:0005739	mitochondrion
0.37	GO:0072562	blood microparticle
0.37	GO:0031012	extracellular matrix
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0009986	cell surface
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus

sp|Q6EIZ0|K1C10_CANLF
Keratin, type I cytoskeletal 10
Search

0.87	Keratin 10 (Epidermolytic hyperkeratosis; keratosis palmaris et plantaris)

0.56	GO:0030216	keratinocyte differentiation
0.52	GO:0018149	peptide cross-linking
0.44	GO:0045104	intermediate filament cytoskeleton organization
0.42	GO:0051798	positive regulation of hair follicle development
0.42	GO:0042633	hair cycle
0.42	GO:0048730	epidermis morphogenesis
0.42	GO:0098773	skin epidermis development
0.41	GO:0022404	molting cycle process
0.41	GO:0030307	positive regulation of cell growth
0.41	GO:0097435	supramolecular fiber organization

0.62	GO:0005198	structural molecule activity
0.45	GO:0032395	MHC class II receptor activity
0.44	GO:0042289	MHC class II protein binding
0.36	GO:0008092	cytoskeletal protein binding
0.35	GO:0097110	scaffold protein binding

0.79	GO:0005882	intermediate filament
0.53	GO:0001533	cornified envelope
0.40	GO:0070062	extracellular exosome
0.39	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.33	GO:0036338	viral membrane

sp|Q6EIZ1|K22E_CANLF
Keratin, type II cytoskeletal 2 epidermal
Search

0.93	Keratin, type II cytoskeletal 2 epidermal

0.57	GO:0043588	skin development
0.55	GO:0045104	intermediate filament cytoskeleton organization
0.53	GO:0008544	epidermis development
0.53	GO:0032980	keratinocyte activation
0.53	GO:0018149	peptide cross-linking
0.52	GO:0051546	keratinocyte migration
0.51	GO:0043616	keratinocyte proliferation
0.49	GO:0030855	epithelial cell differentiation
0.45	GO:0048468	cell development
0.45	GO:0097435	supramolecular fiber organization

0.62	GO:0005198	structural molecule activity
0.44	GO:0008092	cytoskeletal protein binding
0.40	GO:0030246	carbohydrate binding
0.36	GO:0097110	scaffold protein binding
0.35	GO:1990254	keratin filament binding
0.33	GO:0004872	receptor activity

0.83	GO:0045095	keratin filament
0.54	GO:0001533	cornified envelope
0.40	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.35	GO:0031012	extracellular matrix
0.35	GO:0072562	blood microparticle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.33	GO:0009986	cell surface
0.33	GO:0005739	mitochondrion

sp|Q6F3J0|NFKB1_CANLF
Nuclear factor NF-kappa-B p105 subunit
Search

NFKB1

0.96	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0045083	negative regulation of interleukin-12 biosynthetic process
0.61	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity
0.61	GO:1900127	positive regulation of hyaluronan biosynthetic process
0.61	GO:0071316	cellular response to nicotine
0.60	GO:2000630	positive regulation of miRNA metabolic process
0.59	GO:0007165	signal transduction
0.59	GO:0071354	cellular response to interleukin-6
0.59	GO:0035994	response to muscle stretch
0.58	GO:1904385	cellular response to angiotensin

0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.56	GO:0042805	actinin binding
0.54	GO:0003682	chromatin binding
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.51	GO:0008134	transcription factor binding
0.33	GO:0031072	heat shock protein binding

0.61	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0070013	intracellular organelle lumen
0.48	GO:0033256	I-kappaB/NF-kappaB complex
0.45	GO:0005739	mitochondrion
0.44	GO:0044446	intracellular organelle part
0.36	GO:0042581	specific granule
0.36	GO:0031983	vesicle lumen
0.34	GO:0005576	extracellular region
0.33	GO:0043005	neuron projection

sp|Q6J3Q7|COX17_CANLF
Cytochrome c oxidase copper chaperone
Search

COX17

0.94	Mitochondrial cytochrome c oxidase copper chaperone

0.78	GO:0006825	copper ion transport
0.54	GO:1904734	positive regulation of electron transfer activity
0.54	GO:1904959	regulation of cytochrome-c oxidase activity
0.53	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.50	GO:0032414	positive regulation of ion transmembrane transporter activity
0.50	GO:1904064	positive regulation of cation transmembrane transport
0.48	GO:0008284	positive regulation of cell proliferation
0.43	GO:0046688	response to copper ion
0.39	GO:0007507	heart development
0.39	GO:0007420	brain development

0.85	GO:0016531	copper chaperone activity
0.53	GO:1903136	cuprous ion binding
0.37	GO:0008047	enzyme activator activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016874	ligase activity

0.79	GO:0005758	mitochondrial intermembrane space
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016874

sp|Q6JAN1|INVS_CANLF
Inversin
Search

INVS

0.64

Inversin

0.82	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.48	GO:0016055	Wnt signaling pathway
0.46	GO:0007275	multicellular organism development
0.40	GO:0060429	epithelium development

0.49

GO:0005516

calmodulin binding

0.45	GO:0005856	cytoskeleton
0.43	GO:0097543	ciliary inversin compartment
0.42	GO:0097546	ciliary base
0.41	GO:0099512	supramolecular fiber
0.38	GO:0005634	nucleus
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q6JLC9|ZN331_CANLF
Zinc finger protein 331
Search

0.59	LOW QUALITY PROTEIN: zinc finger protein 331

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.39	GO:0097659	nucleic acid-templated transcription
0.38	GO:0010467	gene expression
0.37	GO:0034645	cellular macromolecule biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|Q6K1J1|UDB31_CANLF
UDP-glucuronosyltransferase 2B31
Search

0.54	UDP-glucuronosyltransferase

0.49	GO:0052695	cellular glucuronidation
0.40	GO:0008202	steroid metabolic process
0.38	GO:0006805	xenobiotic metabolic process
0.37	GO:0034754	cellular hormone metabolic process
0.37	GO:0018879	biphenyl metabolic process
0.37	GO:0071394	cellular response to testosterone stimulus
0.37	GO:0071361	cellular response to ethanol
0.36	GO:0071378	cellular response to growth hormone stimulus
0.36	GO:0071385	cellular response to glucocorticoid stimulus
0.36	GO:0032496	response to lipopolysaccharide

0.81	GO:0015020	glucuronosyltransferase activity
0.40	GO:0001972	retinoic acid binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0005635	nuclear envelope
0.33	GO:0098805	whole membrane
0.33	GO:0019867	outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.4.1.17

GO:0015020

sp|Q6L7I9|IL21_CANLF
Interleukin-21
Search

IL21

0.86	Interleukin

0.74	GO:0007260	tyrosine phosphorylation of STAT protein
0.74	GO:0006955	immune response
0.74	GO:0032740	positive regulation of interleukin-17 production
0.73	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
0.72	GO:0030890	positive regulation of B cell proliferation
0.71	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.70	GO:0042102	positive regulation of T cell proliferation
0.70	GO:0010469	regulation of receptor activity
0.68	GO:0048469	cell maturation
0.45	GO:0045078	positive regulation of interferon-gamma biosynthetic process

0.79	GO:0005126	cytokine receptor binding
0.75	GO:0005125	cytokine activity
0.68	GO:0070851	growth factor receptor binding

0.73	GO:0005615	extracellular space
0.41	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q6Q308|PLEK_CANLF
Pleckstrin
Search

PLEK

0.97	Pleckstrin

0.63	GO:0010925	positive regulation of inositol-polyphosphate 5-phosphatase activity
0.63	GO:0010920	negative regulation of inositol phosphate biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.62	GO:0030845	phospholipase C-inhibiting G-protein coupled receptor signaling pathway
0.62	GO:0060305	regulation of cell diameter
0.61	GO:0070560	protein secretion by platelet
0.60	GO:0033625	positive regulation of integrin activation
0.60	GO:0010572	positive regulation of platelet activation
0.59	GO:0070493	thrombin-activated receptor signaling pathway
0.58	GO:0031529	ruffle organization

0.59	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.59	GO:0005080	protein kinase C binding
0.52	GO:0042803	protein homodimerization activity

0.58	GO:0032587	ruffle membrane
0.45	GO:0005622	intracellular
0.33	GO:0005576	extracellular region

sp|Q6Q7I7|PDGFB_CANLF
Platelet-derived growth factor subunit B
Search

PDGFB

0.97	Platelet-derived growth factor subunit B

0.75	GO:0010469	regulation of receptor activity
0.66	GO:0072126	positive regulation of glomerular mesangial cell proliferation
0.65	GO:1900238	regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
0.65	GO:2000591	positive regulation of metanephric mesenchymal cell migration
0.65	GO:1900127	positive regulation of hyaluronan biosynthetic process
0.64	GO:1905176	positive regulation of vascular smooth muscle cell dedifferentiation
0.64	GO:1905064	negative regulation of vascular smooth muscle cell differentiation
0.63	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
0.63	GO:0010544	negative regulation of platelet activation
0.63	GO:0031954	positive regulation of protein autophosphorylation

0.78	GO:0008083	growth factor activity
0.63	GO:0005161	platelet-derived growth factor receptor binding
0.63	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.62	GO:0048407	platelet-derived growth factor binding
0.61	GO:0042056	chemoattractant activity
0.58	GO:0005518	collagen binding
0.55	GO:0042803	protein homodimerization activity
0.53	GO:0046982	protein heterodimerization activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.55	GO:0009986	cell surface
0.45	GO:0005615	extracellular space
0.42	GO:0016323	basolateral plasma membrane
0.38	GO:0005622	intracellular
0.37	GO:0031012	extracellular matrix
0.36	GO:0031983	vesicle lumen
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|Q6Q7P4|41_CANLF
Protein 4.1
Search

EPB41

0.97	Erythrocyte membrane protein band 4.1

0.83	GO:0030866	cortical actin cytoskeleton organization
0.67	GO:1904778	positive regulation of protein localization to cell cortex
0.63	GO:0032092	positive regulation of protein binding
0.54	GO:0008360	regulation of cell shape
0.48	GO:0031032	actomyosin structure organization
0.42	GO:0006461	protein complex assembly

0.72	GO:0003779	actin binding
0.63	GO:0047485	protein N-terminus binding
0.62	GO:0051219	phosphoprotein binding
0.62	GO:0005545	1-phosphatidylinositol binding
0.62	GO:0008022	protein C-terminus binding
0.61	GO:0005198	structural molecule activity
0.37	GO:0030507	spectrin binding

0.69	GO:0005856	cytoskeleton
0.62	GO:0099738	cell cortex region
0.54	GO:0030054	cell junction
0.50	GO:0005829	cytosol
0.48	GO:0043234	protein complex
0.46	GO:0014069	postsynaptic density
0.46	GO:0005886	plasma membrane
0.44	GO:0098562	cytoplasmic side of membrane
0.30	GO:0016021	integral component of membrane

sp|Q6QMY5|ERR1_CANLF
Steroid hormone receptor ERR1
Search

ESRRA

0.97	Steroid hormone receptor ERR1

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.42	GO:0019827	stem cell population maintenance
0.41	GO:1900078	positive regulation of cellular response to insulin stimulus
0.41	GO:0032355	response to estradiol

0.80	GO:0003707	steroid hormone receptor activity
0.79	GO:0005496	steroid binding
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0019904	protein domain specific binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.34	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.34	GO:0000993	RNA polymerase II core binding

0.61	GO:0005634	nucleus
0.56	GO:0045171	intercellular bridge
0.49	GO:0015630	microtubule cytoskeleton
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.34	GO:0000793	condensed chromosome
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.32	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32

GO:0016491

sp|Q6QNF3|PGFRB_CANLF
Platelet-derived growth factor receptor beta
Search

PDGFRB

0.67	Platelet-derived growth factor receptor alpha

0.76	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.59	GO:0014911	positive regulation of smooth muscle cell migration
0.59	GO:0010863	positive regulation of phospholipase C activity
0.59	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.58	GO:0006935	chemotaxis
0.58	GO:0048661	positive regulation of smooth muscle cell proliferation
0.57	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.57	GO:0007275	multicellular organism development

0.78	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.61	GO:0038085	vascular endothelial growth factor binding
0.59	GO:0048407	platelet-derived growth factor binding
0.59	GO:0005161	platelet-derived growth factor receptor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0019901	protein kinase binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0043548	phosphatidylinositol 3-kinase binding

0.70	GO:0043202	lysosomal lumen
0.58	GO:0031410	cytoplasmic vesicle
0.50	GO:0005794	Golgi apparatus
0.48	GO:0031226	intrinsic component of plasma membrane
0.40	GO:0016324	apical plasma membrane
0.38	GO:0009986	cell surface
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.78	EC:2.7.10.1	GO:0004714
0.36	KEGG:R04545	GO:0046934

sp|Q6QNF4|HGFA_CANLF
Hepatocyte growth factor activator
Search

HGFAC

0.96	Hepatocyte growth factor activator

0.61	GO:0006508	proteolysis
0.44	GO:0050878	regulation of body fluid levels
0.43	GO:0050817	coagulation
0.43	GO:0042060	wound healing
0.37	GO:0050819	negative regulation of coagulation
0.37	GO:0061045	negative regulation of wound healing
0.36	GO:0006898	receptor-mediated endocytosis
0.35	GO:0030514	negative regulation of BMP signaling pathway
0.35	GO:0002542	Factor XII activation
0.35	GO:0010756	positive regulation of plasminogen activation

0.69	GO:0004252	serine-type endopeptidase activity
0.45	GO:0005509	calcium ion binding
0.37	GO:0005044	scavenger receptor activity
0.35	GO:0002020	protease binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0030695	GTPase regulator activity

0.62	GO:0005576	extracellular region
0.52	GO:0005791	rough endoplasmic reticulum
0.38	GO:0097180	serine protease inhibitor complex
0.35	GO:0005829	cytosol
0.34	GO:0031982	vesicle
0.33	GO:0005886	plasma membrane
0.33	GO:0031225	anchored component of membrane
0.33	GO:0097223	sperm part
0.32	GO:0019898	extrinsic component of membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|Q6R755|BCL2_CANLF
Apoptosis regulator Bcl-2
Search

BCL2

0.87	3-ketodihydrosphingosine reductase

0.78	GO:0043066	negative regulation of apoptotic process
0.74	GO:0006915	apoptotic process
0.64	GO:0032848	negative regulation of cellular pH reduction
0.63	GO:0043375	CD8-positive, alpha-beta T cell lineage commitment
0.62	GO:0014042	positive regulation of neuron maturation
0.62	GO:0021747	cochlear nucleus development
0.62	GO:0002326	B cell lineage commitment
0.62	GO:0046671	negative regulation of retinal cell programmed cell death
0.62	GO:0045636	positive regulation of melanocyte differentiation
0.61	GO:0038034	signal transduction in absence of ligand

0.61	GO:0051434	BH3 domain binding
0.59	GO:0051721	protein phosphatase 2A binding
0.57	GO:0002020	protease binding
0.57	GO:0016248	channel inhibitor activity
0.54	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0046982	protein heterodimerization activity
0.53	GO:0042803	protein homodimerization activity
0.52	GO:0008134	transcription factor binding
0.49	GO:0022803	passive transmembrane transporter activity
0.47	GO:0043565	sequence-specific DNA binding

0.57	GO:0043209	myelin sheath
0.57	GO:0031965	nuclear membrane
0.56	GO:0005741	mitochondrial outer membrane
0.53	GO:0046930	pore complex
0.52	GO:0005789	endoplasmic reticulum membrane
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0097136	Bcl-2 family protein complex
0.33	GO:0005813	centrosome

0.31

GO:0016491

sp|Q6RH31|PSN1_CANLF
Presenilin-1
Search

PSEN1

0.80	Presenilin

0.81	GO:0007219	Notch signaling pathway
0.78	GO:0042987	amyloid precursor protein catabolic process
0.75	GO:0016485	protein processing
0.60	GO:0050435	amyloid-beta metabolic process
0.60	GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis
0.59	GO:1904797	negative regulation of core promoter binding
0.59	GO:0006509	membrane protein ectodomain proteolysis
0.59	GO:0021870	Cajal-Retzius cell differentiation
0.59	GO:1905908	positive regulation of amyloid fibril formation
0.58	GO:0002265	astrocyte activation involved in immune response

0.77	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving
0.55	GO:0008013	beta-catenin binding
0.55	GO:0030165	PDZ domain binding
0.54	GO:0045296	cadherin binding
0.52	GO:0005262	calcium channel activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0003723	RNA binding

0.73	GO:0000139	Golgi membrane
0.71	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.71	GO:0098827	endoplasmic reticulum subcompartment
0.59	GO:0070765	gamma-secretase complex
0.58	GO:0005790	smooth endoplasmic reticulum
0.57	GO:0035253	ciliary rootlet
0.57	GO:0016235	aggresome
0.57	GO:0043198	dendritic shaft
0.55	GO:0030426	growth cone
0.54	GO:0098857	membrane microdomain

0.77

EC:3.4.23

GO:0042500

sp|Q6S9C0|CXA1_CANLF
Gap junction alpha-1 protein
Search

GJA1

0.64	Gap junction alpha-1 protein (Fragment)

0.80	GO:0007507	heart development
0.75	GO:0007267	cell-cell signaling
0.55	GO:0055085	transmembrane transport
0.55	GO:0010644	cell communication by electrical coupling
0.52	GO:0060156	milk ejection reflex
0.51	GO:0010643	cell communication by chemical coupling
0.50	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization
0.50	GO:0030308	negative regulation of cell growth
0.50	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.49	GO:0002070	epithelial cell maturation

0.57	GO:0022857	transmembrane transporter activity
0.49	GO:0097110	scaffold protein binding
0.48	GO:1990782	protein tyrosine kinase binding
0.48	GO:0048487	beta-tubulin binding
0.44	GO:0004871	signal transducer activity
0.44	GO:0005102	receptor binding
0.39	GO:0030165	PDZ domain binding
0.38	GO:0071253	connexin binding
0.38	GO:0017124	SH3 domain binding
0.38	GO:0097718	disordered domain specific binding

0.84	GO:0005922	connexin complex
0.56	GO:0014704	intercalated disc
0.48	GO:0016328	lateral plasma membrane
0.47	GO:0005913	cell-cell adherens junction
0.47	GO:0016324	apical plasma membrane
0.46	GO:0043292	contractile fiber
0.46	GO:0005654	nucleoplasm
0.46	GO:0005882	intermediate filament
0.44	GO:0012505	endomembrane system
0.43	GO:0005739	mitochondrion

sp|Q6SLL5|CDN1B_CANLF
Cyclin-dependent kinase inhibitor 1B
Search

CDKN1B

0.85	Cyclin dependent kinase inhibitor

0.84	GO:0007050	cell cycle arrest
0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.76	GO:0042127	regulation of cell proliferation
0.65	GO:1902746	regulation of lens fiber cell differentiation
0.64	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.63	GO:0071236	cellular response to antibiotic
0.63	GO:0071285	cellular response to lithium ion
0.62	GO:0048102	autophagic cell death
0.61	GO:0031116	positive regulation of microtubule polymerization
0.60	GO:0000082	G1/S transition of mitotic cell cycle

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.59	GO:0019903	protein phosphatase binding
0.58	GO:0030332	cyclin binding
0.56	GO:0019901	protein kinase binding
0.55	GO:0032403	protein complex binding
0.52	GO:0016301	kinase activity
0.42	GO:0030544	Hsp70 protein binding
0.40	GO:0051087	chaperone binding
0.37	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity
0.36	GO:0060089	molecular transducer activity

0.61	GO:0005634	nucleus
0.61	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.51	GO:0005829	cytosol
0.41	GO:0005768	endosome
0.36	GO:0043234	protein complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:1902554	serine/threonine protein kinase complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.36

EC:2.7.1

GO:0016773

sp|Q6TDU1|MGMT_CANLF
Methylated-DNA--protein-cysteine methyltransferase
Search

MGMT

0.46	Methylated-DNA--protein-cysteine methyltransferase

0.65	GO:0006281	DNA repair
0.63	GO:0032259	methylation
0.55	GO:0035510	DNA dealkylation
0.55	GO:2000781	positive regulation of double-strand break repair
0.53	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.51	GO:0060548	negative regulation of cell death
0.43	GO:0051593	response to folic acid
0.42	GO:0060644	mammary gland epithelial cell differentiation
0.42	GO:0071479	cellular response to ionizing radiation
0.41	GO:0045471	response to ethanol

0.78	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity
0.38	GO:0005509	calcium ion binding
0.37	GO:0003677	DNA binding
0.35	GO:0009008	DNA-methyltransferase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.48	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.1.1.63

GO:0003908

sp|Q6TEQ7|ANXA2_CANLF
Annexin A2
Search

ANXA2

0.60

Annexin

0.72	GO:0043086	negative regulation of catalytic activity
0.59	GO:0052362	catabolism by host of symbiont protein
0.59	GO:0044147	negative regulation of development of symbiont involved in interaction with host
0.59	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding
0.59	GO:1905599	positive regulation of low-density lipoprotein receptor activity
0.59	GO:1905581	positive regulation of low-density lipoprotein particle clearance
0.59	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport
0.59	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.58	GO:0036035	osteoclast development
0.58	GO:0052405	negative regulation by host of symbiont molecular function

0.85	GO:0004859	phospholipase inhibitor activity
0.81	GO:0005544	calcium-dependent phospholipid binding
0.71	GO:0008092	cytoskeletal protein binding
0.69	GO:0005509	calcium ion binding
0.57	GO:0098641	cadherin binding involved in cell-cell adhesion
0.56	GO:0044548	S100 protein binding
0.55	GO:0048306	calcium-dependent protein binding
0.55	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.54	GO:0002020	protease binding
0.50	GO:0042802	identical protein binding

0.58	GO:1990667	PCSK9-AnxA2 complex
0.54	GO:0005913	cell-cell adherens junction
0.54	GO:0035749	myelin sheath adaxonal region
0.54	GO:0031902	late endosome membrane
0.54	GO:0030496	midbody
0.53	GO:0005811	lipid droplet
0.53	GO:0070062	extracellular exosome
0.53	GO:0005765	lysosomal membrane
0.53	GO:0043220	Schmidt-Lanterman incisure
0.52	GO:0098857	membrane microdomain

tr|Q6TN20|Q6TN20_CANLF
Cathelicidin
Search

CAMP

0.93	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.61	GO:0009617	response to bacterium
0.49	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.47	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.47	GO:0044130	negative regulation of growth of symbiont in host
0.46	GO:0051851	modification by host of symbiont morphology or physiology
0.45	GO:0031640	killing of cells of other organism
0.44	GO:0051818	disruption of cells of other organism involved in symbiotic interaction
0.38	GO:0019835	cytolysis
0.37	GO:0009620	response to fungus

0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.47	GO:0042581	specific granule
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0034774	secretory granule lumen
0.33	GO:0042995	cell projection
0.30	GO:0016020	membrane

sp|Q6UKI2|AMNLS_CANLF
Protein amnionless
Search

AMN

0.95	Amnion associated transmembrane protein

0.80	GO:0043001	Golgi to plasma membrane protein transport
0.78	GO:0007588	excretion
0.72	GO:0015889	cobalamin transport
0.67	GO:0006898	receptor-mediated endocytosis

0.68

GO:0005102

receptor binding

0.76	GO:0016324	apical plasma membrane
0.75	GO:0030139	endocytic vesicle
0.68	GO:0005615	extracellular space
0.45	GO:0031526	brush border membrane
0.44	GO:1903561	extracellular vesicle
0.38	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q6UKZ8|GDF8_CANLF
Growth/differentiation factor 8
Search

MSTN

0.94	Growth differentiation factor 8

0.76	GO:2000818	negative regulation of myoblast proliferation
0.76	GO:0010469	regulation of receptor activity
0.75	GO:0014859	negative regulation of skeletal muscle cell proliferation
0.75	GO:0048642	negative regulation of skeletal muscle tissue development
0.74	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.73	GO:2001014	regulation of skeletal muscle cell differentiation
0.67	GO:0045596	negative regulation of cell differentiation
0.59	GO:0033002	muscle cell proliferation
0.59	GO:0014732	skeletal muscle atrophy
0.59	GO:0048631	regulation of skeletal muscle tissue growth

0.78	GO:0008083	growth factor activity
0.59	GO:0008201	heparin binding
0.55	GO:0042802	identical protein binding
0.53	GO:0005125	cytokine activity
0.47	GO:0046983	protein dimerization activity
0.45	GO:0005160	transforming growth factor beta receptor binding

0.66	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q6UR05|MRP1_CANLF
Multidrug resistance-associated protein 1
Search

ABCC1

0.80	LOW QUALITY PROTEIN: multidrug resistance-associated protein 1

0.55	GO:0055085	transmembrane transport
0.48	GO:0099039	sphingolipid translocation
0.45	GO:0042908	xenobiotic transport
0.45	GO:0034635	glutathione transport
0.44	GO:0045332	phospholipid translocation
0.42	GO:0015893	drug transport
0.41	GO:0071585	detoxification of cadmium ion
0.37	GO:0060326	cell chemotaxis
0.36	GO:1905701	positive regulation of drug transmembrane export
0.35	GO:0033700	phospholipid efflux

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046623	sphingolipid-translocating ATPase activity
0.48	GO:0034634	glutathione transmembrane transporter activity
0.45	GO:0042910	xenobiotic transmembrane transporter activity
0.44	GO:0004012	phospholipid-translocating ATPase activity
0.43	GO:0015238	drug transmembrane transporter activity
0.35	GO:0005324	long-chain fatty acid transporter activity

0.50	GO:0016323	basolateral plasma membrane
0.44	GO:0005887	integral component of plasma membrane
0.36	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm

0.44	EC:3.6.3.1	GO:0004012
0.34	KEGG:R04371	GO:0004409

sp|Q6URC2|HMGA1_CANLF
High mobility group protein HMG-I/HMG-Y
Search

HMGA1

0.97	High mobility group protein HMG-I/HMG-Y

0.60	GO:0090402	oncogene-induced cell senescence
0.59	GO:0035986	senescence-associated heterochromatin focus assembly
0.58	GO:2000774	positive regulation of cellular senescence
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0042127	regulation of cell proliferation
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:1902679	negative regulation of RNA biosynthetic process
0.48	GO:0009615	response to virus

0.57	GO:0042975	peroxisome proliferator activated receptor binding
0.56	GO:0046965	retinoid X receptor binding
0.55	GO:0003680	AT DNA binding
0.53	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.52	GO:0001158	enhancer sequence-specific DNA binding
0.47	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.46	GO:0019899	enzyme binding
0.44	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.43	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0003682	chromatin binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.40	GO:0071141	SMAD protein complex
0.40	GO:0005667	transcription factor complex
0.37	GO:0070013	intracellular organelle lumen
0.37	GO:0005925	focal adhesion
0.37	GO:0032993	protein-DNA complex
0.34	GO:0005829	cytosol

0.47

EC:4.2.99.18

GO:0003906

sp|Q6W3F4|AA2BR_CANLF
Adenosine receptor A2b
Search

ADORA2B

0.91	Adenosine receptor A2

0.85	GO:0001973	adenosine receptor signaling pathway
0.56	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.56	GO:0002880	regulation of chronic inflammatory response to non-antigenic stimulus
0.54	GO:0002678	positive regulation of chronic inflammatory response
0.54	GO:0060087	relaxation of vascular smooth muscle
0.53	GO:0033008	positive regulation of mast cell activation involved in immune response
0.53	GO:0043302	positive regulation of leukocyte degranulation
0.53	GO:0002888	positive regulation of myeloid leukocyte mediated immunity
0.53	GO:0031284	positive regulation of guanylate cyclase activity
0.53	GO:0043304	regulation of mast cell degranulation

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.42	GO:0042802	identical protein binding
0.42	GO:0019899	enzyme binding
0.39	GO:0031802	type 5 metabotropic glutamate receptor binding
0.38	GO:0051393	alpha-actinin binding
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0016519	gastric inhibitory peptide receptor activity

0.55	GO:0005886	plasma membrane
0.43	GO:0098794	postsynapse
0.38	GO:0044304	main axon
0.38	GO:0032279	asymmetric synapse
0.38	GO:0048786	presynaptic active zone
0.37	GO:0043025	neuronal cell body
0.37	GO:0005622	intracellular
0.37	GO:0030425	dendrite
0.37	GO:0031252	cell leading edge
0.36	GO:0099512	supramolecular fiber

sp|Q6WIT9|HPRT_CANLF
Hypoxanthine-guanine phosphoribosyltransferase
Search

HPRT1

0.50	Hypoxanthine-guanine phosphoribosyltransferase

0.78	GO:0032264	IMP salvage
0.75	GO:0006166	purine ribonucleoside salvage
0.59	GO:0046038	GMP catabolic process
0.58	GO:0006178	guanine salvage
0.58	GO:0045964	positive regulation of dopamine metabolic process
0.54	GO:0051289	protein homotetramerization
0.54	GO:0046100	hypoxanthine metabolic process
0.54	GO:0007625	grooming behavior
0.54	GO:0021756	striatum development
0.54	GO:0001975	response to amphetamine

0.79	GO:0004422	hypoxanthine phosphoribosyltransferase activity
0.79	GO:0052657	guanine phosphoribosyltransferase activity
0.53	GO:0046872	metal ion binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.50	GO:0042803	protein homodimerization activity

0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome

0.79	EC:2.4.2.8	GO:0004422
0.79	KEGG:R01132	GO:0004422

sp|Q6WZ18|NGB_CANLF
Neuroglobin
Search

NGB

0.96	Neuroglobin

0.79	GO:0015671	oxygen transport
0.42	GO:0001666	response to hypoxia
0.37	GO:0006493	protein O-linked glycosylation
0.37	GO:0097502	mannosylation
0.36	GO:0006915	apoptotic process
0.35	GO:1903206	negative regulation of hydrogen peroxide-induced cell death
0.35	GO:0010039	response to iron ion
0.35	GO:0055114	oxidation-reduction process
0.35	GO:0007568	aging
0.34	GO:0007601	visual perception

0.79	GO:0005344	oxygen carrier activity
0.63	GO:0020037	heme binding
0.53	GO:0046872	metal ion binding
0.49	GO:0019825	oxygen binding
0.40	GO:0098809	nitrite reductase activity
0.37	GO:0000030	mannosyltransferase activity
0.34	GO:0005515	protein binding

0.46	GO:0043204	perikaryon
0.35	GO:0005739	mitochondrion
0.34	GO:0043005	neuron projection
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.37

GO:0000030

sp|Q6X7V3|INSL3_CANLF
Insulin-like 3
Search

INSL3

0.90	Insulin like 3

0.75	GO:0010469	regulation of receptor activity
0.50	GO:0090303	positive regulation of wound healing
0.49	GO:0010634	positive regulation of epithelial cell migration
0.45	GO:0008584	male gonad development
0.44	GO:0007276	gamete generation
0.44	GO:2000018	regulation of male gonad development
0.44	GO:0043950	positive regulation of cAMP-mediated signaling
0.43	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.42	GO:0071695	anatomical structure maturation
0.42	GO:0048469	cell maturation

0.78	GO:0005179	hormone activity
0.49	GO:0002020	protease binding
0.42	GO:0001664	G-protein coupled receptor binding
0.41	GO:0005158	insulin receptor binding

0.66	GO:0005576	extracellular region
0.41	GO:0048471	perinuclear region of cytoplasm

sp|Q6XPZ3|PAG15_CANLF
Group XV phospholipase A2
Search

PLA2G15

0.93	Putative lecithin:cholesterol acyltransferase lcat/acyl-ceramide synthase

0.63	GO:0006629	lipid metabolic process
0.50	GO:0097164	ammonium ion metabolic process
0.48	GO:0046434	organophosphate catabolic process
0.45	GO:1901565	organonitrogen compound catabolic process
0.44	GO:0044248	cellular catabolic process
0.43	GO:0043603	cellular amide metabolic process
0.42	GO:0006796	phosphate-containing compound metabolic process
0.39	GO:0034372	very-low-density lipoprotein particle remodeling
0.38	GO:0034375	high-density lipoprotein particle remodeling
0.38	GO:0043691	reverse cholesterol transport

0.74	GO:0008374	O-acyltransferase activity
0.56	GO:0047499	calcium-independent phospholipase A2 activity
0.39	GO:0034186	apolipoprotein A-I binding
0.38	GO:0004622	lysophospholipase activity
0.34	GO:0005543	phospholipid binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.51	GO:0005615	extracellular space
0.48	GO:0005654	nucleoplasm
0.43	GO:0005739	mitochondrion
0.39	GO:0005764	lysosome
0.38	GO:1990777	lipoprotein particle
0.36	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:2.3.1

GO:0008374

sp|Q6XXX9|5HT1A_CANLF
5-hydroxytryptamine receptor 1A
Search

HTR1A

0.93	5-hydroxytryptamine receptor

0.84	GO:0042310	vasoconstriction
0.84	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.84	GO:0050795	regulation of behavior
0.82	GO:0046883	regulation of hormone secretion
0.79	GO:0008283	cell proliferation
0.64	GO:0014062	regulation of serotonin secretion
0.62	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.62	GO:0042053	regulation of dopamine metabolic process
0.62	GO:0042428	serotonin metabolic process
0.61	GO:0035640	exploration behavior

0.85	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.63	GO:0090722	receptor-receptor interaction
0.51	GO:0051378	serotonin binding
0.35	GO:0001965	G-protein alpha-subunit binding
0.32	GO:0008144	drug binding

0.67	GO:0005887	integral component of plasma membrane
0.36	GO:0043203	axon hillock
0.31	GO:0005622	intracellular

sp|Q6Y4Q5|MMP3_CANLF
Stromelysin-1
Search

0.71	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.58	GO:0032461	positive regulation of protein oligomerization
0.57	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.53	GO:0030574	collagen catabolic process
0.48	GO:0030334	regulation of cell migration
0.43	GO:0022617	extracellular matrix disassembly
0.43	GO:0042060	wound healing
0.41	GO:0009888	tissue development
0.41	GO:1902741	positive regulation of interferon-alpha secretion
0.41	GO:0060340	positive regulation of type I interferon-mediated signaling pathway

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.43	GO:0005518	collagen binding
0.40	GO:0001047	core promoter binding
0.40	GO:0005509	calcium ion binding
0.37	GO:0004252	serine-type endopeptidase activity
0.37	GO:0043565	sequence-specific DNA binding

0.74	GO:0031012	extracellular matrix
0.41	GO:0005615	extracellular space
0.40	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.37	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0030425	dendrite
0.35	GO:0044297	cell body
0.34	GO:0005581	collagen trimer
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.70

EC:3.4.24

GO:0004222

sp|Q6YKA4|HMGB1_CANLF
High mobility group protein B1
Search

HMGB1

0.82	High mobility group box 1

0.57	GO:0032392	DNA geometric change
0.57	GO:0051103	DNA ligation involved in DNA repair
0.52	GO:0097350	neutrophil clearance
0.52	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.51	GO:0002643	regulation of tolerance induction
0.51	GO:1990774	tumor necrosis factor secretion
0.51	GO:0032072	regulation of restriction endodeoxyribonuclease activity
0.51	GO:0050716	positive regulation of interleukin-1 secretion
0.51	GO:0035711	T-helper 1 cell activation
0.50	GO:0032425	positive regulation of mismatch repair

0.72	GO:0097100	supercoiled DNA binding
0.71	GO:0000405	bubble DNA binding
0.69	GO:0008301	DNA binding, bending
0.68	GO:0000400	four-way junction DNA binding
0.49	GO:0019958	C-X-C chemokine binding
0.49	GO:0001786	phosphatidylserine binding
0.49	GO:0070182	DNA polymerase binding
0.48	GO:0070491	repressing transcription factor binding
0.47	GO:0005178	integrin binding
0.46	GO:0001530	lipopolysaccharide binding

0.58	GO:0005634	nucleus
0.50	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.47	GO:0005694	chromosome
0.46	GO:0017053	transcriptional repressor complex
0.46	GO:0005768	endosome
0.45	GO:0005615	extracellular space
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.44	GO:0009986	cell surface
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0043005	neuron projection

0.40

EC:4

GO:0016829

sp|Q711A6|HMGN2_CANLF
Non-histone chromosomal protein HMG-17
Search

HMGN2

0.94	High mobility group nucleosome-binding domain-containing protein 4

0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0031640	killing of cells of other organism
0.36	GO:0040034	regulation of development, heterochronic
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0061098	positive regulation of protein tyrosine kinase activity
0.34	GO:0008154	actin polymerization or depolymerization
0.33	GO:0006334	nucleosome assembly
0.33	GO:0019538	protein metabolic process
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:1901566	organonitrogen compound biosynthetic process

0.85	GO:0031492	nucleosomal DNA binding
0.34	GO:0030296	protein tyrosine kinase activator activity
0.34	GO:0004181	metallocarboxypeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0008270	zinc ion binding
0.33	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.36	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.34

EC:3.4.17

GO:0004181

sp|Q712G9|ID3_CANLF
DNA-binding protein inhibitor ID-3
Search

ID3

0.97	DNA-binding protein inhibitor ID-3-A

0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.66	GO:0072750	cellular response to leptomycin B
0.62	GO:0045667	regulation of osteoblast differentiation
0.62	GO:0045662	negative regulation of myoblast differentiation
0.61	GO:0030903	notochord development
0.61	GO:0048511	rhythmic process
0.60	GO:0030279	negative regulation of ossification
0.60	GO:0001656	metanephros development
0.59	GO:0043433	negative regulation of DNA binding transcription factor activity
0.59	GO:0042476	odontogenesis

0.68	GO:0046983	protein dimerization activity
0.66	GO:1901707	leptomycin B binding
0.56	GO:0008134	transcription factor binding
0.55	GO:0019904	protein domain specific binding
0.47	GO:0003700	DNA binding transcription factor activity
0.45	GO:0003677	DNA binding
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex

0.34

EC:1.8.4 EC:1.8.4.11

GO:0008113

sp|Q71DR4|CNTFR_CANLF
Ciliary neurotrophic factor receptor subunit alpha
Search

CNTFR

0.97	Ciliary neurotrophic factor receptor subunit alpha

0.77	GO:0019221	cytokine-mediated signaling pathway
0.64	GO:0003360	brainstem development
0.62	GO:0001967	suckling behavior
0.59	GO:0043524	negative regulation of neuron apoptotic process
0.58	GO:0060538	skeletal muscle organ development
0.57	GO:0007548	sex differentiation
0.56	GO:0008284	positive regulation of cell proliferation
0.42	GO:0048680	positive regulation of axon regeneration

0.79	GO:0004896	cytokine receptor activity
0.59	GO:0019955	cytokine binding
0.52	GO:0005102	receptor binding

0.64	GO:0097059	CNTFR-CLCF1 complex
0.63	GO:0070110	ciliary neurotrophic factor receptor complex
0.57	GO:0016324	apical plasma membrane
0.41	GO:0031225	anchored component of membrane
0.35	GO:0019898	extrinsic component of membrane

sp|Q75V93|CRSP2_CANLF
Calcitonin receptor-stimulating peptide 2
Search

0.92	Calcitonin receptor-stimulating peptide 2

0.76	GO:0010469	regulation of receptor activity
0.47	GO:0001984	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
0.47	GO:0045779	negative regulation of bone resorption
0.47	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.47	GO:0007190	activation of adenylate cyclase activity
0.46	GO:0031645	negative regulation of neurological system process
0.46	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.45	GO:0045986	negative regulation of smooth muscle contraction
0.45	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.45	GO:1990090	cellular response to nerve growth factor stimulus

0.79	GO:0005179	hormone activity
0.47	GO:0031716	calcitonin receptor binding
0.41	GO:0042802	identical protein binding
0.36	GO:0032403	protein complex binding

0.66	GO:0005576	extracellular region
0.44	GO:0043195	terminal bouton
0.43	GO:0043025	neuronal cell body
0.35	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q75V94|CRSP1_CANLF
Calcitonin receptor-stimulating peptide 1
Search

0.92	Calcitonin receptor-stimulating peptide 1

0.76	GO:0010469	regulation of receptor activity
0.49	GO:0001984	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
0.48	GO:0007190	activation of adenylate cyclase activity
0.47	GO:0045779	negative regulation of bone resorption
0.47	GO:0031645	negative regulation of neurological system process
0.47	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.47	GO:0045986	negative regulation of smooth muscle contraction
0.47	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.47	GO:1990090	cellular response to nerve growth factor stimulus
0.47	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway

0.79	GO:0005179	hormone activity
0.49	GO:0031716	calcitonin receptor binding
0.41	GO:0042802	identical protein binding
0.38	GO:0032403	protein complex binding

0.66	GO:0005576	extracellular region
0.46	GO:0043195	terminal bouton
0.44	GO:0043025	neuronal cell body
0.36	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q75W64|AICDA_CANLF
Single-stranded DNA cytosine deaminase
Search

AICDA

0.96	Single-stranded DNA cytosine deaminase

0.55	GO:0016445	somatic diversification of immunoglobulins
0.55	GO:0090310	negative regulation of methylation-dependent chromatin silencing
0.55	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response
0.55	GO:0009972	cytidine deamination
0.54	GO:0002312	B cell activation involved in immune response
0.54	GO:0097752	regulation of DNA stability
0.54	GO:0002566	somatic diversification of immune receptors via somatic mutation
0.53	GO:0071222	cellular response to lipopolysaccharide
0.53	GO:0016444	somatic cell DNA recombination
0.51	GO:0080111	DNA demethylation

0.71	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.63	GO:0008270	zinc ion binding
0.51	GO:0019239	deaminase activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0042802	identical protein binding

0.49	GO:0000178	exosome (RNase complex)
0.43	GO:0005634	nucleus
0.39	GO:0001527	microfibril
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.71

EC:3.5.4

GO:0016814

sp|Q75ZY9|MET_CANLF
Hepatocyte growth factor receptor
Search

MET

0.95	Hepatocyte growth factor receptor

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.75	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.73	GO:2001028	positive regulation of endothelial cell chemotaxis
0.70	GO:0050918	positive chemotaxis
0.67	GO:0071526	semaphorin-plexin signaling pathway
0.58	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.58	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.57	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death
0.57	GO:0001886	endothelial cell morphogenesis
0.56	GO:0051497	negative regulation of stress fiber assembly

0.77	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0019903	protein phosphatase binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0043274	phospholipase binding
0.36	GO:0043548	phosphatidylinositol 3-kinase binding

0.55	GO:0009925	basal plasma membrane
0.37	GO:0098794	postsynapse
0.37	GO:0009986	cell surface
0.36	GO:0060076	excitatory synapse
0.36	GO:0036126	sperm flagellum
0.36	GO:0032279	asymmetric synapse
0.36	GO:0008290	F-actin capping protein complex
0.36	GO:0005576	extracellular region
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite

0.77	EC:2.7.10.1	GO:0004714
0.37	KEGG:R04545	GO:0046934

sp|Q765Z4|EDN3_CANLF
Endothelin-3
Search

EDN3

0.97	Endothelin-3

0.85	GO:0019229	regulation of vasoconstriction
0.51	GO:0042310	vasoconstriction
0.51	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.50	GO:0008284	positive regulation of cell proliferation
0.50	GO:0030334	regulation of cell migration
0.50	GO:0051050	positive regulation of transport
0.50	GO:0014821	phasic smooth muscle contraction
0.50	GO:0010460	positive regulation of heart rate
0.49	GO:0014033	neural crest cell differentiation
0.49	GO:0014031	mesenchymal cell development

0.51	GO:0031708	endothelin B receptor binding
0.46	GO:0005179	hormone activity
0.42	GO:0031707	endothelin A receptor binding
0.39	GO:0005125	cytokine activity
0.34	GO:0004459	L-lactate dehydrogenase activity
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.35	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

EC:1.1.1.27

GO:0004459

sp|Q767J3|DNAS1_CANLF
Deoxyribonuclease-1
Search

DNASE1

0.63	Deoxyribonuclease

0.76	GO:0006308	DNA catabolic process
0.61	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.59	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.59	GO:0002283	neutrophil activation involved in immune response
0.58	GO:0002673	regulation of acute inflammatory response
0.50	GO:0003335	corneocyte development
0.47	GO:0001942	hair follicle development
0.43	GO:0006915	apoptotic process
0.34	GO:0010623	programmed cell death involved in cell development
0.33	GO:0022411	cellular component disassembly

0.71	GO:0004536	deoxyribonuclease activity
0.61	GO:0004519	endonuclease activity
0.42	GO:0003779	actin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.43	GO:0005634	nucleus
0.40	GO:0012505	endomembrane system
0.40	GO:0005576	extracellular region
0.39	GO:0031967	organelle envelope
0.36	GO:0031982	vesicle
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q76HI7|AP2B_CANLF
Transcription factor AP-2-beta
Search

TFAP2B

0.96	Transcription factor AP-2-beta

0.61	GO:0097276	cellular creatinine homeostasis
0.61	GO:0097277	cellular urea homeostasis
0.61	GO:0097275	cellular ammonia homeostasis
0.60	GO:0097070	ductus arteriosus closure
0.59	GO:0043525	positive regulation of neuron apoptotic process
0.59	GO:0035810	positive regulation of urine volume
0.59	GO:0072044	collecting duct development
0.59	GO:0003091	renal water homeostasis
0.59	GO:0072017	distal tubule development
0.58	GO:0048485	sympathetic nervous system development

0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.57	GO:0001106	RNA polymerase II transcription corepressor activity
0.57	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.57	GO:0001105	RNA polymerase II transcription coactivator activity
0.56	GO:0001158	enhancer sequence-specific DNA binding
0.53	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.39	GO:0003682	chromatin binding
0.39	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q76IQ3|TY3H_CANLF
Tyrosine 3-monooxygenase
Search

0.88	Tyrosine hydroxylase

0.80	GO:0042423	catecholamine biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.62	GO:0007617	mating behavior
0.60	GO:0042417	dopamine metabolic process
0.57	GO:0007625	grooming behavior
0.57	GO:0071625	vocalization behavior
0.56	GO:0035176	social behavior
0.56	GO:0042414	epinephrine metabolic process
0.55	GO:0060416	response to growth hormone
0.54	GO:0001963	synaptic transmission, dopaminergic

0.83	GO:0004511	tyrosine 3-monooxygenase activity
0.62	GO:0005506	iron ion binding
0.46	GO:0019899	enzyme binding
0.42	GO:0004510	tryptophan 5-monooxygenase activity
0.38	GO:0034617	tetrahydrobiopterin binding
0.38	GO:0035240	dopamine binding
0.37	GO:0019825	oxygen binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0016597	amino acid binding
0.34	GO:0005179	hormone activity

0.54	GO:0033162	melanosome membrane
0.53	GO:0005790	smooth endoplasmic reticulum
0.53	GO:0043204	perikaryon
0.50	GO:0030424	axon
0.48	GO:0009898	cytoplasmic side of plasma membrane
0.43	GO:0005634	nucleus
0.37	GO:0043679	axon terminus
0.37	GO:0008021	synaptic vesicle
0.37	GO:0030425	dendrite
0.35	GO:0070852	cell body fiber

0.83

EC:1.14.16.2

GO:0004511

tr|Q76LT7|Q76LT7_CANLF
Bcl-xL
Search

0.97	Anti-apoptotic regulator Bcl-xL

0.74	GO:0042981	regulation of apoptotic process
0.74	GO:0006915	apoptotic process
0.63	GO:0043069	negative regulation of programmed cell death
0.62	GO:0038034	signal transduction in absence of ligand
0.60	GO:0046902	regulation of mitochondrial membrane permeability
0.60	GO:0051881	regulation of mitochondrial membrane potential
0.60	GO:0070997	neuron death
0.60	GO:0010332	response to gamma radiation
0.59	GO:0001541	ovarian follicle development
0.59	GO:0060154	cellular process regulating host cell cycle in response to virus

0.63	GO:0051434	BH3 domain binding
0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0042802	identical protein binding
0.52	GO:0019901	protein kinase binding
0.46	GO:0051721	protein phosphatase 2A binding
0.45	GO:0002020	protease binding
0.44	GO:0016248	channel inhibitor activity
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0008134	transcription factor binding
0.40	GO:0022803	passive transmembrane transporter activity

0.58	GO:0097136	Bcl-2 family protein complex
0.56	GO:0005741	mitochondrial outer membrane
0.53	GO:0005813	centrosome
0.51	GO:0005783	endoplasmic reticulum
0.51	GO:0005829	cytosol
0.47	GO:0031965	nuclear membrane
0.45	GO:0043209	myelin sheath
0.43	GO:0046930	pore complex
0.42	GO:0070013	intracellular organelle lumen
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

sp|Q7YQC6|HSP71_CANLF
Heat shock 70 kDa protein 1
Search

0.53	Inducible heat shock protein 70

0.52	GO:0042026	protein refolding
0.52	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0010638	positive regulation of organelle organization
0.51	GO:0010821	regulation of mitochondrion organization
0.51	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.50	GO:1903533	regulation of protein targeting
0.50	GO:0090316	positive regulation of intracellular protein transport
0.48	GO:0010968	regulation of microtubule nucleation
0.47	GO:1901673	regulation of mitotic spindle assembly
0.44	GO:0032273	positive regulation of protein polymerization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0031072	heat shock protein binding
0.47	GO:0051082	unfolded protein binding
0.41	GO:0055131	C3HC4-type RING finger domain binding
0.41	GO:0031249	denatured protein binding
0.41	GO:0001106	RNA polymerase II transcription corepressor activity

0.53	GO:0002199	zona pellucida receptor complex
0.50	GO:0008180	COP9 signalosome
0.49	GO:0044297	cell body
0.46	GO:0005829	cytosol
0.44	GO:0005815	microtubule organizing center
0.41	GO:0072562	blood microparticle
0.40	GO:0016235	aggresome
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0070062	extracellular exosome
0.39	GO:0048471	perinuclear region of cytoplasm

0.34	EC:6.1.1.9	GO:0004832
0.34	KEGG:R03665	GO:0004832

sp|Q7YR70|AAMP_CANLF
Angio-associated migratory cell protein
Search

AAMP

0.92	Angio-associated migratory protein (Predicted)

0.61	GO:0042273	ribosomal large subunit biogenesis
0.54	GO:0014909	smooth muscle cell migration
0.48	GO:0010595	positive regulation of endothelial cell migration
0.47	GO:0001525	angiogenesis
0.44	GO:0030154	cell differentiation
0.39	GO:0045766	positive regulation of angiogenesis

0.57	GO:0051082	unfolded protein binding
0.53	GO:0008201	heparin binding

0.81	GO:0045171	intercellular bridge
0.68	GO:0015630	microtubule cytoskeleton
0.65	GO:0005829	cytosol
0.63	GO:0030687	preribosome, large subunit precursor
0.54	GO:0009986	cell surface
0.39	GO:0005886	plasma membrane

sp|Q7YR73|ICOS_CANLF
Inducible T-cell costimulator
Search

ICOS

0.97	Inducible T-cell co-stimulator

0.52	GO:0002517	T cell tolerance induction
0.50	GO:0031295	T cell costimulation
0.46	GO:0098609	cell-cell adhesion
0.39	GO:0051897	positive regulation of protein kinase B signaling
0.37	GO:0046854	phosphatidylinositol phosphorylation
0.37	GO:0006955	immune response

0.40	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005515	protein binding

0.68	GO:0009897	external side of plasma membrane
0.57	GO:0005887	integral component of plasma membrane
0.36	GO:0005576	extracellular region

0.40	EC:2.7.1.153	GO:0046934
0.40	KEGG:R04545	GO:0046934

sp|Q7YRB4|BDNF_CANLF
Brain-derived neurotrophic factor
Search

BDNF

0.59	Brain-derived neurotrophic factor

0.75	GO:0010469	regulation of receptor activity
0.51	GO:1900122	positive regulation of receptor binding
0.51	GO:0048672	positive regulation of collateral sprouting
0.51	GO:0048668	collateral sprouting
0.49	GO:0051965	positive regulation of synapse assembly
0.49	GO:0007416	synapse assembly
0.43	GO:0043524	negative regulation of neuron apoptotic process
0.41	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.40	GO:0007267	cell-cell signaling
0.37	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway

0.78	GO:0008083	growth factor activity
0.45	GO:0005169	neurotrophin TRKB receptor binding

0.66	GO:0005576	extracellular region
0.47	GO:0016607	nuclear speck
0.41	GO:0005739	mitochondrion
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0031410	cytoplasmic vesicle
0.36	GO:0030425	dendrite
0.36	GO:0030424	axon
0.36	GO:0098794	postsynapse
0.35	GO:0043204	perikaryon
0.35	GO:0043679	axon terminus

sp|Q7YRB7|AOFB_CANLF
Amine oxidase [flavin-containing] B
Search

MAOB

0.49	Amine oxidase [flavin-containing] B

0.52	GO:0055114	oxidation-reduction process
0.52	GO:0042420	dopamine catabolic process
0.41	GO:0042135	neurotransmitter catabolic process
0.39	GO:0014063	negative regulation of serotonin secretion
0.39	GO:0010269	response to selenium ion
0.39	GO:0045964	positive regulation of dopamine metabolic process
0.39	GO:0051412	response to corticosterone
0.39	GO:0010044	response to aluminum ion
0.38	GO:0045471	response to ethanol
0.37	GO:0032496	response to lipopolysaccharide

0.54	GO:0016491	oxidoreductase activity
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0051378	serotonin binding

0.48	GO:0005739	mitochondrion
0.46	GO:0031967	organelle envelope
0.46	GO:0031090	organelle membrane
0.43	GO:0098805	whole membrane
0.41	GO:0019867	outer membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

sp|Q7YRF1|AP3B1_CANLF
AP-3 complex subunit beta-1
Search

AP3B1

0.81	AP-3 complex subunit beta

0.68	GO:0006886	intracellular protein transport
0.67	GO:0016192	vesicle-mediated transport
0.54	GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib
0.54	GO:0051138	positive regulation of NK T cell differentiation
0.54	GO:0008089	anterograde axonal transport
0.53	GO:0047496	vesicle transport along microtubule
0.53	GO:0032438	melanosome organization
0.52	GO:0061462	protein localization to lysosome
0.52	GO:0097480	establishment of synaptic vesicle localization
0.51	GO:0007041	lysosomal transport

0.53	GO:0030742	GTP-dependent protein binding
0.50	GO:0019903	protein phosphatase binding
0.38	GO:0030276	clathrin binding
0.35	GO:0048487	beta-tubulin binding

0.80	GO:0030123	AP-3 adaptor complex
0.68	GO:0030131	clathrin adaptor complex
0.53	GO:1904115	axon cytoplasm
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0005764	lysosome
0.37	GO:0044437	vacuolar part
0.36	GO:0030136	clathrin-coated vesicle
0.35	GO:0005802	trans-Golgi network
0.35	GO:0030659	cytoplasmic vesicle membrane

sp|Q7YRJ7|SOX9_CANLF
Transcription factor SOX-9
Search

SOX9

0.94	SRY sex determining region Y-box 9

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.66	GO:0060767	epithelial cell proliferation involved in prostate gland development
0.65	GO:0060784	regulation of cell proliferation involved in tissue homeostasis
0.65	GO:0060516	primary prostatic bud elongation
0.64	GO:2000741	positive regulation of mesenchymal stem cell differentiation
0.64	GO:0072289	metanephric nephron tubule formation
0.64	GO:0019100	male germ-line sex determination
0.64	GO:0060221	retinal rod cell differentiation
0.64	GO:0071504	cellular response to heparin
0.64	GO:0072034	renal vesicle induction

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.60	GO:0035326	enhancer binding
0.60	GO:0001046	core promoter sequence-specific DNA binding
0.58	GO:0097157	pre-mRNA intronic binding
0.58	GO:0034236	protein kinase A catalytic subunit binding
0.57	GO:0003682	chromatin binding
0.55	GO:0008013	beta-catenin binding
0.51	GO:0046982	protein heterodimerization activity
0.48	GO:0004672	protein kinase activity
0.41	GO:0043425	bHLH transcription factor binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q7YRL5|TNR5_CANLF
Tumor necrosis factor receptor superfamily member 5
Search

CD40

0.97	Tumor necrosis factor receptor superfamily member 5

0.84	GO:0042113	B cell activation
0.72	GO:0050776	regulation of immune response
0.66	GO:0090037	positive regulation of protein kinase C signaling
0.65	GO:2000353	positive regulation of endothelial cell apoptotic process
0.65	GO:0051023	regulation of immunoglobulin secretion
0.64	GO:0042832	defense response to protozoan
0.64	GO:0032735	positive regulation of interleukin-12 production
0.63	GO:0043491	protein kinase B signaling
0.63	GO:0002639	positive regulation of immunoglobulin production
0.63	GO:0030890	positive regulation of B cell proliferation

0.65	GO:0004872	receptor activity
0.59	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0003823	antigen binding
0.43	GO:0004871	signal transducer activity
0.41	GO:0019904	protein domain specific binding

0.82	GO:0009897	external side of plasma membrane
0.65	GO:0035631	CD40 receptor complex
0.45	GO:0043196	varicosity
0.45	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0043025	neuronal cell body
0.41	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.35	GO:0005737	cytoplasm

sp|Q7YRU7|DSG3_CANLF
Desmoglein-3
Search

0.95	LOW QUALITY PROTEIN: desmoglein-4

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0030216	keratinocyte differentiation
0.53	GO:0001942	hair follicle development
0.52	GO:0030509	BMP signaling pathway
0.39	GO:0050821	protein stabilization
0.37	GO:0012501	programmed cell death
0.36	GO:0003165	Purkinje myocyte development
0.35	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.35	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.35	GO:0002934	desmosome organization

0.70	GO:0005509	calcium ion binding
0.41	GO:0045295	gamma-catenin binding
0.35	GO:0050839	cell adhesion molecule binding
0.32	GO:0015643	toxic substance binding

0.57	GO:0030057	desmosome
0.55	GO:0005886	plasma membrane
0.40	GO:0070062	extracellular exosome
0.39	GO:0098562	cytoplasmic side of membrane
0.37	GO:0005914	spot adherens junction
0.35	GO:0014704	intercalated disc
0.35	GO:0005829	cytosol
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0045177	apical part of cell
0.32	GO:0031012	extracellular matrix

sp|Q861Q9|TBX4_CANLF
T-box transcription factor TBX4
Search

TBX4

0.97	T-box transcription factor TBX4

0.62	GO:0035108	limb morphogenesis
0.61	GO:0035113	embryonic appendage morphogenesis
0.57	GO:0030324	lung development
0.57	GO:0048705	skeletal system morphogenesis
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0001525	angiogenesis
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0002009	morphogenesis of an epithelium

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.36	GO:0030274	LIM domain binding

0.61	GO:0005634	nucleus
0.35	GO:0097517	contractile actin filament bundle
0.35	GO:0042641	actomyosin
0.35	GO:0005884	actin filament
0.32	GO:0005737	cytoplasm

sp|Q861Y6|NICN1_CANLF
Nicolin-1
Search

NICN1

0.97	Macrophage stimulating 1 receptor (C-met-related tyrosine kinase)

0.55	GO:0006546	glycine catabolic process
0.50	GO:0018095	protein polyglutamylation
0.48	GO:0032259	methylation
0.41	GO:0016310	phosphorylation

0.57	GO:0004047	aminomethyltransferase activity
0.44	GO:0008483	transaminase activity
0.42	GO:0016301	kinase activity

0.57	GO:0005874	microtubule
0.54	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion

0.57

EC:2.1.2.10

GO:0004047

sp|Q862Z3|UROM_CANLF
Uromodulin
Search

0.92	Pancreatic zymogen granule membrane protein GP-2

0.61	GO:0072233	metanephric thick ascending limb development
0.60	GO:0072221	metanephric distal convoluted tubule development
0.60	GO:0072021	ascending thin limb development
0.60	GO:0072236	metanephric loop of Henle development
0.57	GO:0007588	excretion
0.57	GO:0007159	leukocyte cell-cell adhesion
0.57	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.57	GO:1990266	neutrophil migration
0.55	GO:2000021	regulation of ion homeostasis
0.50	GO:0048878	chemical homeostasis

0.62	GO:0005509	calcium ion binding
0.59	GO:0019864	IgG binding
0.40	GO:0005201	extracellular matrix structural constituent
0.37	GO:0003823	antigen binding
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0051537	2 iron, 2 sulfur cluster binding
0.32	GO:0016301	kinase activity
0.32	GO:0050431	transforming growth factor beta binding
0.32	GO:0008061	chitin binding
0.32	GO:0005112	Notch binding

0.64	GO:0005576	extracellular region
0.57	GO:0016324	apical plasma membrane
0.56	GO:0016323	basolateral plasma membrane
0.56	GO:0031225	anchored component of membrane
0.55	GO:0000922	spindle pole
0.53	GO:0005929	cilium
0.42	GO:0031253	cell projection membrane
0.40	GO:0098588	bounding membrane of organelle
0.37	GO:0031982	vesicle
0.36	GO:0045121	membrane raft

0.31

GO:0004252

sp|Q863A2|TBX2_CANLF
T-box transcription factor TBX2
Search

TBX2

0.95

T-box 2

0.83	GO:1901211	negative regulation of cardiac chamber formation
0.83	GO:1901208	negative regulation of heart looping
0.80	GO:0007521	muscle cell fate determination
0.80	GO:0060596	mammary placode formation
0.79	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.79	GO:0060465	pharynx development
0.79	GO:0036302	atrioventricular canal development
0.78	GO:0090398	cellular senescence
0.77	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.77	GO:0003148	outflow tract septum morphogenesis

0.74	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.71	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.66	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus

sp|Q863B4|TFF3_CANLF
Trefoil factor 3
Search

TFF3

0.93	Trefoil factor 3

0.72	GO:0010906	regulation of glucose metabolic process
0.70	GO:0007586	digestion
0.63	GO:0042060	wound healing
0.51	GO:0010669	epithelial structure maintenance
0.46	GO:0003008	system process
0.44	GO:0060455	negative regulation of gastric acid secretion
0.42	GO:0043031	negative regulation of macrophage activation
0.41	GO:0050728	negative regulation of inflammatory response
0.41	GO:0010033	response to organic substance
0.41	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.45	GO:0031723	CXCR4 chemokine receptor binding
0.40	GO:0008083	growth factor activity
0.35	GO:0005198	structural molecule activity

0.70	GO:0030141	secretory granule
0.58	GO:0005615	extracellular space
0.52	GO:0005578	proteinaceous extracellular matrix
0.46	GO:1903561	extracellular vesicle

sp|Q863H1|SFRP2_CANLF
Secreted frizzled-related protein 2
Search

SFRP2

0.97	Testicular tissue protein Li 170

0.74	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.64	GO:0030510	regulation of BMP signaling pathway
0.63	GO:0061185	negative regulation of dermatome development
0.62	GO:2000041	negative regulation of planar cell polarity pathway involved in axis elongation
0.62	GO:0042662	negative regulation of mesodermal cell fate specification
0.61	GO:0071481	cellular response to X-ray
0.61	GO:2000035	regulation of stem cell division
0.61	GO:0043508	negative regulation of JUN kinase activity
0.61	GO:0035412	regulation of catenin import into nucleus

0.61	GO:0017147	Wnt-protein binding
0.60	GO:0061133	endopeptidase activator activity
0.53	GO:0048018	receptor ligand activity
0.50	GO:0042813	Wnt-activated receptor activity
0.45	GO:0004930	G-protein coupled receptor activity
0.37	GO:0001968	fibronectin binding
0.37	GO:0005178	integrin binding

0.65	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q863J2|TFF2_CANLF
Trefoil factor 2
Search

TFF2

0.92	Trefoil factor 2

0.73	GO:0007586	digestion
0.65	GO:0042060	wound healing
0.60	GO:0010906	regulation of glucose metabolic process
0.54	GO:0010669	epithelial structure maintenance
0.48	GO:0003008	system process
0.47	GO:0008285	negative regulation of cell proliferation
0.44	GO:0030154	cell differentiation
0.43	GO:0010469	regulation of receptor activity
0.42	GO:0005975	carbohydrate metabolic process
0.36	GO:0006952	defense response

0.46	GO:0030246	carbohydrate binding
0.45	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.43	GO:0008083	growth factor activity

0.60	GO:0005615	extracellular space
0.59	GO:0030141	secretory granule
0.44	GO:0005578	proteinaceous extracellular matrix
0.38	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:3.2.1

GO:0004553

sp|Q863T4|TFF1_CANLF
Trefoil factor 1
Search

TFF1

0.88	Trefoil factor 1

0.86	GO:0030277	maintenance of gastrointestinal epithelium
0.70	GO:0008285	negative regulation of cell proliferation
0.64	GO:0030154	cell differentiation
0.60	GO:0042060	wound healing
0.48	GO:0010469	regulation of receptor activity
0.46	GO:0035902	response to immobilization stress
0.44	GO:0010039	response to iron ion
0.43	GO:0043434	response to peptide hormone
0.38	GO:0005975	carbohydrate metabolic process

0.49

GO:0008083

growth factor activity

0.56

GO:0005615

extracellular space

sp|Q863Z4|MTPN_CANLF
Myotrophin
Search

MTPN

0.96	Myotrophin

0.80	GO:0014742	positive regulation of muscle hypertrophy
0.79	GO:0010611	regulation of cardiac muscle hypertrophy
0.78	GO:2000812	regulation of barbed-end actin filament capping
0.73	GO:0008361	regulation of cell size
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.51	GO:0030307	positive regulation of cell growth
0.49	GO:0021684	cerebellar granular layer formation
0.48	GO:0043403	skeletal muscle tissue regeneration
0.48	GO:0021533	cell differentiation in hindbrain
0.47	GO:0051247	positive regulation of protein metabolic process

0.46	GO:0002039	p53 binding
0.44	GO:0018024	histone-lysine N-methyltransferase activity
0.41	GO:0043565	sequence-specific DNA binding
0.39	GO:0008270	zinc ion binding
0.37	GO:0019901	protein kinase binding
0.36	GO:0008318	protein prenyltransferase activity
0.34	GO:0008081	phosphoric diester hydrolase activity

0.74	GO:0008290	F-actin capping protein complex
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0030424	axon
0.47	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.41	GO:0070062	extracellular exosome
0.40	GO:0005694	chromosome
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.44

EC:2.1.1.43

GO:0018024

sp|Q864L3|SCN2B_CANLF
Sodium channel subunit beta-2
Search

SCN2B

0.97	Sodium voltage-gated channel beta subunit 2

0.66	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.66	GO:0086012	membrane depolarization during cardiac muscle cell action potential
0.66	GO:0065009	regulation of molecular function
0.64	GO:0086002	cardiac muscle cell action potential involved in contraction
0.64	GO:0086091	regulation of heart rate by cardiac conduction
0.63	GO:1902305	regulation of sodium ion transmembrane transport
0.59	GO:0035725	sodium ion transmembrane transport
0.47	GO:0046684	response to pyrethroid
0.41	GO:0007399	nervous system development
0.39	GO:0046629	gamma-delta T cell activation

0.85	GO:0017080	sodium channel regulator activity
0.67	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential
0.40	GO:0022832	voltage-gated channel activity
0.40	GO:0022839	ion gated channel activity
0.40	GO:0008381	mechanosensitive ion channel activity
0.34	GO:0005515	protein binding

0.83

GO:0001518

voltage-gated sodium channel complex

sp|Q865C0|CAH6_CANLF
Carbonic anhydrase 6
Search

CA6

0.85	Stress-inducible intra-cellular carbonic anhydrase isozyme VI

0.71	GO:0006730	one-carbon metabolic process
0.60	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.37	GO:0015701	bicarbonate transport
0.32	GO:0006414	translational elongation

0.77	GO:0004089	carbonate dehydratase activity
0.62	GO:0008270	zinc ion binding
0.32	GO:0003746	translation elongation factor activity

0.52	GO:0005615	extracellular space
0.41	GO:0005829	cytosol
0.38	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.77

EC:4.2.1.1

GO:0004089

sp|Q865S0|RCAS1_CANLF
Receptor-binding cancer antigen expressed on SiSo cells
Search

EBAG9

0.97	Receptor-binding cancer antigen expressed on SiSo cells

0.76	GO:0006915	apoptotic process
0.35	GO:0001558	regulation of cell growth

0.36	GO:0016505	peptidase activator activity involved in apoptotic process
0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.72	GO:0000139	Golgi membrane
0.38	GO:0030141	secretory granule
0.30	GO:0031224	intrinsic component of membrane

sp|Q865S3|ARHG2_CANLF
Rho guanine nucleotide exchange factor 2
Search

ARHGEF2

0.92	Rho guanine nucleotide exchange factor 2

0.77	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.59	GO:0071802	negative regulation of podosome assembly
0.59	GO:0071225	cellular response to muramyl dipeptide
0.58	GO:2001224	positive regulation of neuron migration
0.58	GO:0055059	asymmetric neuroblast division
0.57	GO:0007026	negative regulation of microtubule depolymerization
0.57	GO:0032760	positive regulation of tumor necrosis factor production
0.56	GO:0032755	positive regulation of interleukin-6 production

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.57	GO:0048365	Rac GTPase binding
0.52	GO:0046872	metal ion binding
0.51	GO:0008017	microtubule binding
0.37	GO:0008134	transcription factor binding

0.56	GO:0032587	ruffle membrane
0.55	GO:0002102	podosome
0.55	GO:0043198	dendritic shaft
0.53	GO:0014069	postsynaptic density
0.52	GO:0043025	neuronal cell body
0.50	GO:0005874	microtubule
0.50	GO:0031982	vesicle
0.42	GO:0005923	bicellular tight junction
0.41	GO:0005819	spindle
0.40	GO:0005794	Golgi apparatus

sp|Q866G7|TSCOT_CANLF
Thymic stromal cotransporter homolog
Search

SLC46A2

0.97	Thymic stromal cotransporter

0.65	GO:0070233	negative regulation of T cell apoptotic process
0.64	GO:0043029	T cell homeostasis
0.63	GO:0048538	thymus development
0.62	GO:0045580	regulation of T cell differentiation
0.53	GO:0055085	transmembrane transport
0.34	GO:0006281	DNA repair

0.46

GO:0005215

transporter activity

0.57	GO:0009986	cell surface
0.37	GO:0070876	SOSS complex
0.37	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q866Y9|ZACN_CANLF
Zinc-activated ligand-gated ion channel
Search

ZACN

0.97	Zinc-activated ligand-gated ion channel

0.79	GO:0010043	response to zinc ion
0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.45	GO:0006812	cation transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity
0.52	GO:0140135	mechanosensitive cation channel activity
0.36	GO:0008270	zinc ion binding

0.52	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q867B0|CELA1_CANLF
Chymotrypsin-like elastase family member 1
Search

CELA1

0.93	Pancreatic elastase

0.61	GO:0006508	proteolysis
0.57	GO:0060309	elastin catabolic process
0.55	GO:0061113	pancreas morphogenesis
0.54	GO:0031017	exocrine pancreas development
0.52	GO:0035264	multicellular organism growth
0.52	GO:0048771	tissue remodeling
0.52	GO:0045766	positive regulation of angiogenesis
0.50	GO:0006954	inflammatory response
0.50	GO:0009791	post-embryonic development
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0016740	transferase activity

0.44	GO:0005615	extracellular space
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|Q867B7|HGF_CANLF
Hepatocyte growth factor
Search

HGF

0.95	Hepatocyte growth factor a

0.69	GO:0010469	regulation of receptor activity
0.69	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.66	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
0.66	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death
0.65	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.65	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.64	GO:1902947	regulation of tau-protein kinase activity
0.63	GO:0051450	myoblast proliferation
0.63	GO:0050918	positive chemotaxis
0.62	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.71	GO:0048018	receptor ligand activity
0.69	GO:0004252	serine-type endopeptidase activity
0.55	GO:0042802	identical protein binding
0.39	GO:0046982	protein heterodimerization activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity

0.48	GO:0005615	extracellular space
0.37	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

0.69	EC:3.4.21	GO:0004252
0.37	KEGG:R04545	GO:0046934

sp|Q8HX86|TPMT_CANLF
Thiopurine S-methyltransferase
Search

TPMT

0.67	Thiopurine S-methyltransferase

0.63	GO:0032259	methylation
0.35	GO:0033574	response to testosterone
0.35	GO:0010038	response to metal ion
0.32	GO:0046483	heterocycle metabolic process
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process
0.32	GO:0006807	nitrogen compound metabolic process
0.30	GO:0044238	primary metabolic process

0.85	GO:0008119	thiopurine S-methyltransferase activity
0.32	GO:0016874	ligase activity

0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome

0.85

EC:2.1.1.67

GO:0008119

sp|Q8HXG3|RHPN2_CANLF
Rhophilin-2
Search

RHPN2

0.62	Rhophilin Rho GTPase binding protein 2

0.59

GO:0007165

signal transduction

0.41	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005829	cytosol

sp|Q8HY39|PRAF1_CANLF
Prenylated Rab acceptor protein 1
Search

RABAC1

0.97	Prenylated Rab acceptor protein 1

0.46

GO:0016192

vesicle-mediated transport

0.72	GO:0070064	proline-rich region binding
0.68	GO:0008022	protein C-terminus binding
0.66	GO:0042802	identical protein binding
0.51	GO:0030674	protein binding, bridging

0.82	GO:0008021	synaptic vesicle
0.75	GO:0030054	cell junction
0.72	GO:0005794	Golgi apparatus
0.56	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q8HY67|AN32A_CANLF
Acidic leucine-rich nuclear phosphoprotein 32 family member A
Search

ANP32A

0.91	Acidic leucine-rich nuclear phosphoprotein 32 family member A

0.71	GO:0006913	nucleocytoplasmic transport
0.68	GO:0043486	histone exchange
0.65	GO:0006334	nucleosome assembly
0.62	GO:0042981	regulation of apoptotic process
0.45	GO:0006351	transcription, DNA-templated
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.44	GO:0035067	negative regulation of histone acetylation
0.43	GO:0010977	negative regulation of neuron projection development

0.65	GO:0042393	histone binding
0.43	GO:0005178	integrin binding
0.43	GO:0008022	protein C-terminus binding
0.40	GO:0003723	RNA binding

0.75	GO:0048471	perinuclear region of cytoplasm
0.67	GO:0005783	endoplasmic reticulum
0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol

sp|Q8HY81|CATS_CANLF
Cathepsin S
Search

CTSS

0.89	LOW QUALITY PROTEIN: cathepsin S

0.62	GO:0034769	basement membrane disassembly
0.61	GO:0006508	proteolysis
0.58	GO:0030574	collagen catabolic process
0.58	GO:0097067	cellular response to thyroid hormone stimulus
0.57	GO:2001259	positive regulation of cation channel activity
0.56	GO:0010447	response to acidic pH
0.54	GO:0002250	adaptive immune response
0.54	GO:0048002	antigen processing and presentation of peptide antigen
0.52	GO:0044257	cellular protein catabolic process
0.50	GO:0051604	protein maturation

0.72	GO:0008234	cysteine-type peptidase activity
0.59	GO:0001968	fibronectin binding
0.57	GO:0043394	proteoglycan binding
0.57	GO:0043236	laminin binding
0.56	GO:0005518	collagen binding
0.48	GO:0004175	endopeptidase activity
0.35	GO:0017171	serine hydrolase activity
0.35	GO:0070273	phosphatidylinositol-4-phosphate binding

0.56	GO:0005764	lysosome
0.53	GO:0005615	extracellular space
0.38	GO:0031904	endosome lumen
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen
0.35	GO:0005654	nucleoplasm
0.34	GO:0005769	early endosome
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.72

GO:0008234

tr|Q8HYB0|Q8HYB0_CANLF
5-hydroxytryptamine receptor 1A
Search

HTR1A

0.93	5-hydroxytryptamine receptor

0.84	GO:0042310	vasoconstriction
0.84	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.84	GO:0050795	regulation of behavior
0.82	GO:0046883	regulation of hormone secretion
0.79	GO:0008283	cell proliferation
0.64	GO:0014062	regulation of serotonin secretion
0.62	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.62	GO:0042053	regulation of dopamine metabolic process
0.62	GO:0042428	serotonin metabolic process
0.61	GO:0035640	exploration behavior

0.85	GO:0099589	serotonin receptor activity
0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.63	GO:0090722	receptor-receptor interaction
0.51	GO:0051378	serotonin binding
0.35	GO:0001965	G-protein alpha-subunit binding
0.32	GO:0008144	drug binding

0.67	GO:0005887	integral component of plasma membrane
0.36	GO:0043203	axon hillock
0.31	GO:0005622	intracellular

sp|Q8HYB7|PERT_CANLF
Thyroid peroxidase
Search

TPO

0.93	Myeloid-specific peroxidase

0.83	GO:0006590	thyroid hormone generation
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.56	GO:0035162	embryonic hemopoiesis
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0006952	defense response
0.50	GO:0018969	thiocyanate metabolic process
0.48	GO:0002149	hypochlorous acid biosynthetic process
0.46	GO:0009617	response to bacterium
0.45	GO:0042744	hydrogen peroxide catabolic process

0.84	GO:0004447	iodide peroxidase activity
0.63	GO:0020037	heme binding
0.61	GO:0005509	calcium ion binding
0.50	GO:0036393	thiocyanate peroxidase activity
0.42	GO:0008201	heparin binding
0.33	GO:0003682	chromatin binding

0.48	GO:0005615	extracellular space
0.45	GO:0005739	mitochondrion
0.44	GO:0005766	primary lysosome
0.42	GO:0030141	secretory granule
0.37	GO:0005634	nucleus
0.36	GO:0009986	cell surface
0.35	GO:1903561	extracellular vesicle
0.35	GO:0016323	basolateral plasma membrane
0.34	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen

0.84

EC:1.11.1.8

GO:0004447

sp|Q8HYS0|CCL5_CANLF
C-C motif chemokine 5
Search

CCL5

0.76	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.82	GO:0070098	chemokine-mediated signaling pathway
0.78	GO:0006954	inflammatory response
0.75	GO:0009615	response to virus
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.63	GO:0010820	positive regulation of T cell chemotaxis
0.62	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin
0.62	GO:2000503	positive regulation of natural killer cell chemotaxis
0.62	GO:0031584	activation of phospholipase D activity

0.86	GO:0031729	CCR4 chemokine receptor binding
0.86	GO:0031726	CCR1 chemokine receptor binding
0.86	GO:0031730	CCR5 chemokine receptor binding
0.84	GO:0008009	chemokine activity
0.63	GO:0046817	chemokine receptor antagonist activity
0.61	GO:0030298	receptor signaling protein tyrosine kinase activator activity
0.61	GO:0016004	phospholipase activator activity
0.60	GO:0042056	chemoattractant activity
0.58	GO:0043621	protein self-association
0.56	GO:0004435	phosphatidylinositol phospholipase C activity

0.73	GO:0005615	extracellular space
0.39	GO:0005737	cytoplasm

0.56	EC:3.1.4.11	GO:0004435
0.56	KEGG:R03435	GO:0004435

sp|Q8HYS5|MCL1_CANLF
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Search

MCL1

0.91	MCL1, BCL2 family apoptosis regulator b

0.80	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
0.77	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.76	GO:2000811	negative regulation of anoikis
0.75	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.73	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.72	GO:0008637	apoptotic mitochondrial changes
0.67	GO:2001020	regulation of response to DNA damage stimulus
0.67	GO:0034097	response to cytokine
0.65	GO:0010507	negative regulation of autophagy
0.51	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway

0.78	GO:0051434	BH3 domain binding
0.66	GO:0046982	protein heterodimerization activity
0.47	GO:0042803	protein homodimerization activity

0.77	GO:0097136	Bcl-2 family protein complex
0.63	GO:0005759	mitochondrial matrix
0.58	GO:0005829	cytosol
0.54	GO:0005634	nucleus
0.48	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

sp|Q8HYV8|ASB17_CANLF
Ankyrin repeat and SOCS box protein 17
Search

ASB17

0.97	Ankyrin repeat and SOCS box containing protein 17

0.72	GO:0016567	protein ubiquitination
0.60	GO:0035556	intracellular signal transduction
0.39	GO:0043687	post-translational protein modification

0.44

GO:0005622

intracellular

sp|Q8HZM5|GLNA_CANLF
Glutamine synthetase
Search

GLUL

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.49	GO:0008283	cell proliferation
0.49	GO:0009749	response to glucose
0.46	GO:0009267	cellular response to starvation
0.39	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.39	GO:0019676	ammonia assimilation cycle
0.39	GO:0032024	positive regulation of insulin secretion
0.38	GO:0050679	positive regulation of epithelial cell proliferation
0.37	GO:0051260	protein homooligomerization
0.35	GO:0001504	neurotransmitter uptake

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042802	identical protein binding
0.43	GO:0004351	glutamate decarboxylase activity
0.40	GO:0016595	glutamate binding
0.39	GO:0045503	dynein light chain binding
0.37	GO:0030145	manganese ion binding
0.35	GO:0000287	magnesium ion binding

0.51	GO:0097386	glial cell projection
0.48	GO:0043209	myelin sheath
0.47	GO:0044297	cell body
0.45	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0036477	somatodendritic compartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|Q8HZR1|PGH1_CANLF
Prostaglandin G/H synthase 1
Search

PTGS1

0.94	Prostaglandin-endoperoxide synthase 1 (Prostaglandin G/H synthase and cyclooxygenase)

0.86	GO:0019371	cyclooxygenase pathway
0.83	GO:0008217	regulation of blood pressure
0.80	GO:0006954	inflammatory response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0042127	regulation of cell proliferation
0.40	GO:0071471	cellular response to non-ionic osmotic stress
0.40	GO:0031394	positive regulation of prostaglandin biosynthetic process
0.40	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

0.86	GO:0004666	prostaglandin-endoperoxide synthase activity
0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.40	GO:0051213	dioxygenase activity
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0019899	enzyme binding
0.36	GO:0046872	metal ion binding
0.32	GO:0008144	drug binding

0.53	GO:0001750	photoreceptor outer segment
0.48	GO:0012505	endomembrane system
0.43	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0044444	cytoplasmic part
0.40	GO:0031984	organelle subcompartment
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

0.86	EC:1.14.99.1	GO:0004666
0.72	KEGG:R03532	GO:0004601

sp|Q8HZV4|TBD_CANLF
Tubulin delta chain
Search

TUBD1

0.96	Tubulin delta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.39	GO:0007283	spermatogenesis
0.38	GO:0030154	cell differentiation
0.38	GO:0007275	multicellular organism development

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005874	microtubule
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.41	GO:0005814	centriole
0.30	GO:0031224	intrinsic component of membrane

sp|Q8I009|BIRC5_CANLF
Baculoviral IAP repeat-containing protein 5
Search

BIRC5

0.96	Baculoviral IAP repeat-containing protein 5

0.76	GO:0043066	negative regulation of apoptotic process
0.74	GO:0043523	regulation of neuron apoptotic process
0.73	GO:0061469	regulation of type B pancreatic cell proliferation
0.70	GO:0000226	microtubule cytoskeleton organization
0.70	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.68	GO:0007346	regulation of mitotic cell cycle
0.68	GO:1901215	negative regulation of neuron death
0.67	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.64	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.62	GO:0140014	mitotic nuclear division

0.64	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.56	GO:0004842	ubiquitin-protein transferase activity
0.55	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0008017	microtubule binding
0.46	GO:0008536	Ran GTPase binding
0.45	GO:0008270	zinc ion binding
0.43	GO:0046965	retinoid X receptor binding
0.42	GO:0051087	chaperone binding
0.41	GO:0048037	cofactor binding

0.59	GO:0032133	chromosome passenger complex
0.58	GO:0030496	midbody
0.56	GO:0031021	interphase microtubule organizing center
0.56	GO:0000777	condensed chromosome kinetochore
0.55	GO:0005819	spindle
0.54	GO:0005881	cytoplasmic microtubule
0.53	GO:0005814	centriole
0.51	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.40	GO:0070013	intracellular organelle lumen

0.34	EC:3	GO:0016787
0.56	KEGG:R03876	GO:0004842

sp|Q8MIH6|RECO_CANLF
Recoverin
Search

RCVRN

0.97	Recoverin a

0.57	GO:0009416	response to light stimulus
0.53	GO:0051924	regulation of calcium ion transport
0.52	GO:0007601	visual perception
0.51	GO:0009582	detection of abiotic stimulus
0.51	GO:0009581	detection of external stimulus
0.44	GO:0007165	signal transduction
0.36	GO:0010562	positive regulation of phosphorus metabolic process
0.35	GO:0043085	positive regulation of catalytic activity
0.35	GO:0031282	regulation of guanylate cyclase activity
0.35	GO:1904063	negative regulation of cation transmembrane transport

0.70	GO:0005509	calcium ion binding
0.35	GO:0008047	enzyme activator activity
0.35	GO:0010853	cyclase activator activity
0.35	GO:0030249	guanylate cyclase regulator activity
0.34	GO:0019207	kinase regulator activity
0.34	GO:0004354	glutamate dehydrogenase (NADP+) activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0030425	dendrite
0.34	GO:0000139	Golgi membrane
0.34	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:1.4.1.4

GO:0004354

sp|Q8MJ04|RP1_CANLF
Oxygen-regulated protein 1
Search

RP1

0.96	Oxygen-regulated protein 1

0.82	GO:0042461	photoreceptor cell development
0.76	GO:0007601	visual perception
0.69	GO:0042670	retinal cone cell differentiation
0.67	GO:0045494	photoreceptor cell maintenance
0.67	GO:0035082	axoneme assembly
0.65	GO:1902857	positive regulation of non-motile cilium assembly
0.62	GO:0035556	intracellular signal transduction
0.59	GO:0071482	cellular response to light stimulus
0.41	GO:0098869	cellular oxidant detoxification
0.40	GO:0007603	phototransduction, visible light

0.72	GO:0008017	microtubule binding
0.43	GO:0004096	catalase activity
0.39	GO:0020037	heme binding
0.33	GO:0005262	calcium channel activity
0.32	GO:0008083	growth factor activity
0.32	GO:0003677	DNA binding

0.82	GO:0001750	photoreceptor outer segment
0.65	GO:0001917	photoreceptor inner segment
0.64	GO:0097542	ciliary tip
0.63	GO:0005930	axoneme
0.62	GO:0032391	photoreceptor connecting cilium
0.60	GO:0005875	microtubule associated complex
0.40	GO:0005874	microtubule
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:1.11.1.6

GO:0004096

sp|Q8MJ36|HSPB8_CANLF
Heat shock protein beta-8
Search

HSPB8

0.97	LOW QUALITY PROTEIN: heat shock protein beta-8

0.41

GO:1900034

regulation of cellular response to heat

0.72	GO:0042802	identical protein binding
0.39	GO:0004672	protein kinase activity

0.67	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

sp|Q8MJ44|KAPCA_CANLF
cAMP-dependent protein kinase catalytic subunit alpha
Search

PRKACA

0.83	cAMP-dependent protein kinase catalytic subunit alpha

0.62	GO:0006468	protein phosphorylation
0.59	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.56	GO:0001843	neural tube closure
0.56	GO:0070613	regulation of protein processing
0.51	GO:2000810	regulation of bicellular tight junction assembly
0.50	GO:0071374	cellular response to parathyroid hormone stimulus
0.50	GO:0048240	sperm capacitation
0.49	GO:0034605	cellular response to heat
0.49	GO:0071333	cellular response to glucose stimulus
0.49	GO:0071158	positive regulation of cell cycle arrest

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.51	GO:0034237	protein kinase A regulatory subunit binding
0.49	GO:0060089	molecular transducer activity
0.48	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.47	GO:0000287	magnesium ion binding

0.57	GO:0097546	ciliary base
0.57	GO:0045171	intercellular bridge
0.53	GO:0005813	centrosome
0.51	GO:0005952	cAMP-dependent protein kinase complex
0.50	GO:0036126	sperm flagellum
0.50	GO:0001669	acrosomal vesicle
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005829	cytosol
0.48	GO:0044853	plasma membrane raft
0.48	GO:0043197	dendritic spine

0.69

GO:0004674

sp|Q8MJ46|PP1G_CANLF
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Search

PPP1CC

0.49	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.59	GO:0043153	entrainment of circadian clock by photoperiod
0.58	GO:0032922	circadian regulation of gene expression
0.50	GO:0046822	regulation of nucleocytoplasmic transport
0.49	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.47	GO:0048754	branching morphogenesis of an epithelial tube
0.47	GO:0030324	lung development
0.44	GO:0098609	cell-cell adhesion
0.42	GO:0005977	glycogen metabolic process
0.40	GO:0051301	cell division

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.54	GO:0046872	metal ion binding
0.51	GO:0047485	protein N-terminus binding
0.48	GO:0098641	cadherin binding involved in cell-cell adhesion
0.48	GO:0019901	protein kinase binding
0.42	GO:0008157	protein phosphatase 1 binding
0.40	GO:0032403	protein complex binding
0.39	GO:0005521	lamin binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.66	GO:0072357	PTW/PP1 phosphatase complex
0.55	GO:0000784	nuclear chromosome, telomeric region
0.49	GO:0005730	nucleolus
0.48	GO:0005741	mitochondrial outer membrane
0.46	GO:0005913	cell-cell adherens junction
0.46	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.42	GO:0043234	protein complex
0.42	GO:0097610	cell surface furrow

sp|Q8MJ47|PP1B_CANLF
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Search

PPP1CB

0.49	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.51	GO:0042752	regulation of circadian rhythm
0.49	GO:0030155	regulation of cell adhesion
0.46	GO:0032922	circadian regulation of gene expression
0.46	GO:0009648	photoperiodism
0.46	GO:0060028	convergent extension involved in axis elongation
0.41	GO:0005977	glycogen metabolic process
0.41	GO:0001889	liver development
0.40	GO:0009605	response to external stimulus
0.39	GO:0051301	cell division

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.57	GO:0050115	myosin-light-chain-phosphatase activity
0.54	GO:0046872	metal ion binding
0.48	GO:0019901	protein kinase binding
0.42	GO:0046982	protein heterodimerization activity

0.85	GO:0072357	PTW/PP1 phosphatase complex
0.84	GO:0000164	protein phosphatase type 1 complex
0.49	GO:0000784	nuclear chromosome, telomeric region
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0005730	nucleolus
0.39	GO:0005654	nucleoplasm
0.37	GO:0042587	glycogen granule
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.57

EC:3.1.3.53

GO:0050115

tr|Q8MJD1|Q8MJD1_CANLF
Neutrophil elastase
Search

ELANE

0.92	Neutrophil elastase

0.61	GO:0002812	biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.61	GO:0006508	proteolysis
0.61	GO:0070947	neutrophil mediated killing of fungus
0.60	GO:0045079	negative regulation of chemokine biosynthetic process
0.60	GO:0045415	negative regulation of interleukin-8 biosynthetic process
0.60	GO:0070945	neutrophil mediated killing of gram-negative bacterium
0.59	GO:0002438	acute inflammatory response to antigenic stimulus
0.59	GO:0050900	leukocyte migration
0.59	GO:0045416	positive regulation of interleukin-8 biosynthetic process
0.58	GO:0006909	phagocytosis

0.69	GO:0004252	serine-type endopeptidase activity
0.57	GO:0001106	RNA polymerase II transcription corepressor activity
0.56	GO:0002020	protease binding
0.55	GO:0019955	cytokine binding
0.55	GO:0008201	heparin binding
0.43	GO:0005102	receptor binding
0.34	GO:0005509	calcium ion binding

0.59	GO:0030141	secretory granule
0.54	GO:0044421	extracellular region part
0.54	GO:0017053	transcriptional repressor complex
0.51	GO:0009986	cell surface
0.49	GO:0005766	primary lysosome
0.49	GO:0060205	cytoplasmic vesicle lumen
0.48	GO:0005775	vacuolar lumen
0.46	GO:0044853	plasma membrane raft
0.42	GO:0005829	cytosol
0.32	GO:0005634	nucleus

0.69

GO:0004252

sp|Q8MJD7|CNGB3_CANLF
Cyclic nucleotide-gated cation channel beta-3
Search

CNGB3

0.88	cGMP-gated cation channel beta-X

0.77	GO:0007601	visual perception
0.61	GO:0098655	cation transmembrane transport
0.46	GO:0042391	regulation of membrane potential
0.44	GO:0071804	cellular potassium ion transport
0.40	GO:0098660	inorganic ion transmembrane transport
0.38	GO:0035845	photoreceptor cell outer segment organization
0.38	GO:0050962	detection of light stimulus involved in sensory perception
0.37	GO:0045494	photoreceptor cell maintenance
0.37	GO:0009584	detection of visible light
0.36	GO:0007602	phototransduction

0.85	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.58	GO:0030553	cGMP binding
0.45	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0005515	protein binding
0.34	GO:0003777	microtubule motor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding

0.55	GO:0001750	photoreceptor outer segment
0.47	GO:1902495	transmembrane transporter complex
0.42	GO:0005887	integral component of plasma membrane

sp|Q8MJU5|FETA_CANLF
Alpha-fetoprotein
Search

0.76	Serum albumin

0.63	GO:0001542	ovulation from ovarian follicle
0.63	GO:0042448	progesterone metabolic process
0.60	GO:0060395	SMAD protein signal transduction
0.42	GO:0051659	maintenance of mitochondrion location
0.41	GO:0019836	hemolysis by symbiont of host erythrocytes
0.39	GO:0009267	cellular response to starvation
0.39	GO:0043066	negative regulation of apoptotic process
0.36	GO:0031100	animal organ regeneration
0.36	GO:0043687	post-translational protein modification
0.35	GO:0031016	pancreas development

0.41	GO:0005504	fatty acid binding
0.40	GO:0015643	toxic substance binding
0.39	GO:0019825	oxygen binding
0.38	GO:0046872	metal ion binding
0.37	GO:0019842	vitamin binding
0.36	GO:0051087	chaperone binding
0.36	GO:0050662	coenzyme binding
0.36	GO:0042802	identical protein binding
0.35	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.40	GO:0005737	cytoplasm
0.37	GO:0043209	myelin sheath
0.37	GO:1903561	extracellular vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0043234	protein complex
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q8MJW8|CCR4_CANLF
C-C chemokine receptor type 4
Search

CCR4

0.97	C-C motif chemokine receptor 4

0.84	GO:0070098	chemokine-mediated signaling pathway
0.79	GO:0006954	inflammatory response
0.73	GO:0006955	immune response
0.71	GO:0006935	chemotaxis
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0090026	positive regulation of monocyte chemotaxis
0.59	GO:0002507	tolerance induction
0.56	GO:0001764	neuron migration
0.53	GO:0048872	homeostasis of number of cells
0.42	GO:0050927	positive regulation of positive chemotaxis

0.85	GO:0016493	C-C chemokine receptor activity
0.38	GO:0019957	C-C chemokine binding
0.35	GO:0004535	poly(A)-specific ribonuclease activity
0.34	GO:0003779	actin binding
0.33	GO:0008270	zinc ion binding

0.55	GO:0009897	external side of plasma membrane
0.40	GO:0043025	neuronal cell body
0.35	GO:0005768	endosome
0.34	GO:0005887	integral component of plasma membrane

0.35

EC:3.1.13.4

GO:0004535

sp|Q8MKD5|TNNI3_CANLF
Troponin I, cardiac muscle
Search

TNNI3

0.90	High Mr cardiac troponin I

0.60	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions
0.60	GO:0006941	striated muscle contraction
0.58	GO:0060047	heart contraction
0.56	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.55	GO:0001570	vasculogenesis
0.55	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.52	GO:0006874	cellular calcium ion homeostasis
0.52	GO:0050881	musculoskeletal movement
0.52	GO:0032780	negative regulation of ATPase activity
0.41	GO:0006940	regulation of smooth muscle contraction

0.60	GO:0031014	troponin T binding
0.57	GO:0030172	troponin C binding
0.56	GO:0019855	calcium channel inhibitor activity
0.54	GO:0048306	calcium-dependent protein binding
0.53	GO:0003779	actin binding
0.51	GO:0019901	protein kinase binding
0.50	GO:0019904	protein domain specific binding
0.49	GO:0032403	protein complex binding
0.38	GO:0046872	metal ion binding
0.33	GO:0016887	ATPase activity

0.83	GO:0005861	troponin complex
0.56	GO:0097512	cardiac myofibril
0.36	GO:0005634	nucleus
0.34	GO:0005829	cytosol

0.33

GO:0016887

sp|Q8MKI5|CASP3_CANLF
Caspase-3
Search

CASP3

0.94	Caspase 3, apoptosis-related cysteine peptidase a

0.61	GO:0006508	proteolysis
0.59	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress
0.59	GO:0030216	keratinocyte differentiation
0.59	GO:0097194	execution phase of apoptosis
0.58	GO:0030218	erythrocyte differentiation
0.58	GO:0072733	response to staurosporine
0.57	GO:0034349	glial cell apoptotic process
0.57	GO:0046007	negative regulation of activated T cell proliferation
0.56	GO:0030889	negative regulation of B cell proliferation
0.56	GO:0071312	cellular response to alkaloid

0.75	GO:0004197	cysteine-type endopeptidase activity
0.54	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.47	GO:0004190	aspartic-type endopeptidase activity
0.40	GO:0016005	phospholipase A2 activator activity
0.39	GO:0005123	death receptor binding
0.38	GO:0002020	protease binding
0.37	GO:0032403	protein complex binding
0.36	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.35	GO:1990525	BIR domain binding
0.34	GO:0004252	serine-type endopeptidase activity

0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.39	GO:0031264	death-inducing signaling complex
0.38	GO:0098857	membrane microdomain
0.35	GO:0097179	protease inhibitor complex
0.34	GO:0043197	dendritic spine
0.34	GO:0014069	postsynaptic density
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.75

EC:3.4.22

GO:0004197

sp|Q8MKI8|RAD51_CANLF
DNA repair protein RAD51 homolog 1
Search

RAD51

0.74	DNA repair protein RAD51 homolog A

0.84	GO:1990426	mitotic recombination-dependent replication fork processing
0.75	GO:0000724	double-strand break repair via homologous recombination
0.55	GO:0090735	DNA repair complex assembly
0.55	GO:0072757	cellular response to camptothecin
0.54	GO:0051106	positive regulation of DNA ligation
0.54	GO:0072711	cellular response to hydroxyurea
0.53	GO:0010212	response to ionizing radiation
0.53	GO:0006312	mitotic recombination
0.53	GO:0010569	regulation of double-strand break repair via homologous recombination
0.52	GO:0070192	chromosome organization involved in meiotic cell cycle

0.72	GO:0000150	recombinase activity
0.71	GO:0003697	single-stranded DNA binding
0.70	GO:0003690	double-stranded DNA binding
0.69	GO:0008094	DNA-dependent ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0070182	DNA polymerase binding
0.50	GO:0008022	protein C-terminus binding

0.60	GO:0005634	nucleus
0.50	GO:0035861	site of double-strand break
0.50	GO:0000793	condensed chromosome
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0000781	chromosome, telomeric region
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.41	GO:0043234	protein complex

tr|Q8SPQ9|Q8SPQ9_CANLF
Cyclooxygenase 2
Search

PTGS2

0.96	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase)

0.86	GO:0019371	cyclooxygenase pathway
0.83	GO:0008217	regulation of blood pressure
0.80	GO:0006954	inflammatory response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.59	GO:0071471	cellular response to non-ionic osmotic stress
0.59	GO:0031394	positive regulation of prostaglandin biosynthetic process
0.58	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.58	GO:0031622	positive regulation of fever generation
0.57	GO:0090336	positive regulation of brown fat cell differentiation

0.86	GO:0004666	prostaglandin-endoperoxide synthase activity
0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0019899	enzyme binding
0.40	GO:0051213	dioxygenase activity
0.36	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
0.36	GO:0046872	metal ion binding

0.52	GO:0043005	neuron projection
0.50	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.38	GO:0031090	organelle membrane
0.38	GO:0005901	caveola
0.34	GO:0043234	protein complex
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

0.86	EC:1.14.99.1	GO:0004666
0.72	KEGG:R03532	GO:0004601

sp|Q8SPS9|DYLT3_CANLF
Dynein light chain Tctex-type 3
Search

DYNLT3

0.94	Dynein light chain Tctex-type 3

0.58	GO:0019060	intracellular transport of viral protein in host cell
0.49	GO:0007346	regulation of mitotic cell cycle
0.46	GO:0045787	positive regulation of cell cycle
0.43	GO:0051301	cell division
0.43	GO:0007049	cell cycle

0.72	GO:0042802	identical protein binding
0.45	GO:0003774	motor activity

0.83	GO:0005868	cytoplasmic dynein complex
0.73	GO:0000776	kinetochore
0.60	GO:0005881	cytoplasmic microtubule
0.53	GO:0099503	secretory vesicle
0.48	GO:0005818	aster
0.48	GO:0000779	condensed chromosome, centromeric region
0.46	GO:0005876	spindle microtubule
0.46	GO:0072686	mitotic spindle
0.46	GO:0044217	other organism part
0.46	GO:0018995	host

sp|Q8SQ03|CRX_CANLF
Cone-rod homeobox protein
Search

CRX

0.97	Cone-rod homeobox containing gene

0.75	GO:0007623	circadian rhythm
0.72	GO:0007601	visual perception
0.69	GO:0007275	multicellular organism development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0006366	transcription by RNA polymerase II
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0043522	leucine zipper domain binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.41	GO:0035257	nuclear hormone receptor binding
0.36	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex

sp|Q8SQ41|PEPB_CANLF
Pepsin B
Search

PGC

0.92	Progastricsin

0.61	GO:0006508	proteolysis
0.52	GO:0002803	positive regulation of antibacterial peptide production
0.49	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.44	GO:0007586	digestion

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.46	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

sp|Q8SQ72|SGCG_CANLF
Gamma-sarcoglycan
Search

SGCG

0.97	Gamma-sarcoglycan

0.51	GO:0060047	heart contraction
0.50	GO:0048738	cardiac muscle tissue development
0.49	GO:0061061	muscle structure development
0.46	GO:0048468	cell development
0.43	GO:0061024	membrane organization
0.40	GO:0048798	swim bladder inflation
0.39	GO:0007368	determination of left/right symmetry

0.34

GO:0005515

protein binding

0.85	GO:0016012	sarcoglycan complex
0.57	GO:0042383	sarcolemma
0.49	GO:0005654	nucleoplasm
0.38	GO:0005856	cytoskeleton
0.34	GO:0005737	cytoplasm
0.33	GO:0005887	integral component of plasma membrane

sp|Q8WMD0|COMD1_CANLF
COMM domain-containing protein 1
Search

COMMD1

0.97	Copper metabolism domain containing 1

0.80	GO:0055070	copper ion homeostasis
0.61	GO:1902306	negative regulation of sodium ion transmembrane transport
0.61	GO:2000009	negative regulation of protein localization to cell surface
0.57	GO:0048227	plasma membrane to endosome transport
0.57	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.56	GO:0031398	positive regulation of protein ubiquitination
0.56	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.54	GO:0006893	Golgi to plasma membrane transport
0.39	GO:1905751	positive regulation of endosome to plasma membrane protein transport
0.39	GO:1904109	positive regulation of cholesterol import

0.56	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.56	GO:0070300	phosphatidic acid binding
0.56	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.55	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.55	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0005507	copper ion binding
0.36	GO:0019871	sodium channel inhibitor activity
0.36	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0008378	galactosyltransferase activity

0.57	GO:0031462	Cul2-RING ubiquitin ligase complex
0.55	GO:0055037	recycling endosome
0.54	GO:0005769	early endosome
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.39	GO:0010008	endosome membrane
0.37	GO:0070062	extracellular exosome
0.33	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.34

GO:0008378

tr|Q8WMR9|Q8WMR9_CANLF
CMP-sialic acid transporter
Search

SLC35A1

0.91	CMP-sialic acid transporter

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.39	GO:0015782	CMP-N-acetylneuraminate transmembrane transport
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.79	GO:0005351	sugar:proton symporter activity
0.39	GO:0005456	CMP-N-acetylneuraminate transmembrane transporter activity

0.74	GO:0000139	Golgi membrane
0.35	GO:0005887	integral component of plasma membrane

sp|Q8WMS0|S35A2_CANLF
UDP-galactose translocator
Search

SLC35A2

0.94	Solute carrier family 35 (UDP-galactose transporter), member 2

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport

0.79

GO:0005351

sugar:proton symporter activity

0.74	GO:0000139	Golgi membrane
0.53	GO:0005783	endoplasmic reticulum
0.48	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q8WMS3|PPR1A_CANLF
Protein phosphatase 1 regulatory subunit 1A
Search

PPP1R1A

0.97	Phosphatase 1, regulatory (Inhibitor) subunit 1B

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.49	GO:0006469	negative regulation of protein kinase activity
0.41	GO:0005977	glycogen metabolic process
0.35	GO:0006470	protein dephosphorylation

0.83	GO:0004864	protein phosphatase inhibitor activity
0.35	GO:0005515	protein binding
0.35	GO:0004721	phosphoprotein phosphatase activity

0.38	GO:0005615	extracellular space
0.37	GO:0005737	cytoplasm
0.35	GO:0099512	supramolecular fiber
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

EC:3.1.3.16

GO:0004721

sp|Q8WMS6|PP1A_CANLF
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Search

PPP1CA

0.50	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.55	GO:0043153	entrainment of circadian clock by photoperiod
0.53	GO:0032922	circadian regulation of gene expression
0.52	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.50	GO:0002009	morphogenesis of an epithelium
0.50	GO:0030324	lung development
0.49	GO:0001763	morphogenesis of a branching structure
0.48	GO:0035239	tube morphogenesis
0.47	GO:0098609	cell-cell adhesion
0.40	GO:0005977	glycogen metabolic process

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.53	GO:0046872	metal ion binding
0.51	GO:0098641	cadherin binding involved in cell-cell adhesion
0.40	GO:0008157	protein phosphatase 1 binding
0.39	GO:0047485	protein N-terminus binding
0.38	GO:0019901	protein kinase binding
0.38	GO:0032403	protein complex binding
0.37	GO:0043021	ribonucleoprotein complex binding
0.35	GO:0072542	protein phosphatase activator activity
0.35	GO:0005521	lamin binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.71	GO:0072357	PTW/PP1 phosphatase complex
0.50	GO:0000784	nuclear chromosome, telomeric region
0.49	GO:0005913	cell-cell adherens junction
0.46	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.41	GO:0005730	nucleolus
0.40	GO:0042587	glycogen granule
0.39	GO:0005886	plasma membrane
0.39	GO:0043197	dendritic spine

sp|Q8WMU5|FZD6_CANLF
Frizzled-6
Search

FZD6

0.96	Frizzled class receptor 6

0.77	GO:0016055	Wnt signaling pathway
0.67	GO:0007275	multicellular organism development
0.59	GO:0048105	establishment of body hair planar orientation
0.57	GO:0090175	regulation of establishment of planar polarity
0.57	GO:0061351	neural precursor cell proliferation
0.57	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.56	GO:0043433	negative regulation of DNA binding transcription factor activity
0.56	GO:0030168	platelet activation
0.55	GO:0022405	hair cycle process
0.54	GO:0060322	head development

0.85	GO:0042813	Wnt-activated receptor activity
0.59	GO:0017147	Wnt-protein binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0004930	G-protein coupled receptor activity
0.35	GO:0001540	amyloid-beta binding
0.35	GO:0030165	PDZ domain binding

0.58	GO:0016327	apicolateral plasma membrane
0.56	GO:0045177	apical part of cell
0.39	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0009986	cell surface
0.36	GO:0032433	filopodium tip
0.35	GO:0016328	lateral plasma membrane
0.35	GO:0048786	presynaptic active zone
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite

sp|Q8WMX5|S15A1_CANLF
Solute carrier family 15 member 1
Search

SLC15A1

0.55	Proton-dependent gastrointestinal peptide transporter

0.78	GO:0006857	oligopeptide transport
0.55	GO:0055085	transmembrane transport
0.41	GO:0015804	neutral amino acid transport
0.37	GO:0015031	protein transport
0.35	GO:0051956	negative regulation of amino acid transport
0.35	GO:0007586	digestion
0.34	GO:0042121	alginic acid biosynthetic process
0.34	GO:0065009	regulation of molecular function
0.34	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0015992	proton transport

0.71	GO:0035673	oligopeptide transmembrane transporter activity
0.49	GO:0015291	secondary active transmembrane transporter activity
0.41	GO:0015175	neutral amino acid transmembrane transporter activity
0.35	GO:0016248	channel inhibitor activity
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.56	GO:0005903	brush border
0.33	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

sp|Q8WN22|PRKDC_CANLF
DNA-dependent protein kinase catalytic subunit
Search

PRKDC

0.84	DNA-dependent protein kinase catalytic subunit

0.80	GO:0006303	double-strand break repair via nonhomologous end joining
0.65	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint
0.64	GO:0002328	pro-B cell differentiation
0.64	GO:0002326	B cell lineage commitment
0.64	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint
0.63	GO:0033152	immunoglobulin V(D)J recombination
0.63	GO:0031571	mitotic G1 DNA damage checkpoint
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035234	ectopic germ cell programmed cell death
0.62	GO:0033153	T cell receptor V(D)J recombination

0.86	GO:0004677	DNA-dependent protein kinase activity
0.56	GO:0019904	protein domain specific binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0008134	transcription factor binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019899	enzyme binding
0.35	GO:0003723	RNA binding

0.65	GO:0070419	nonhomologous end joining complex
0.61	GO:0005634	nucleus
0.55	GO:0005667	transcription factor complex
0.53	GO:0032993	protein-DNA complex
0.52	GO:0070013	intracellular organelle lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0044446	intracellular organelle part
0.39	GO:0031012	extracellular matrix
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.86

GO:0004677

tr|Q8WN71|Q8WN71_CANLF
Ventricular myosin light chain 2
Search

MYL2

0.96	Cardiac ventricular myosin light chain-2

0.59	GO:0098735	positive regulation of the force of heart contraction
0.58	GO:0042694	muscle cell fate specification
0.57	GO:0055003	cardiac myofibril assembly
0.56	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.56	GO:0060047	heart contraction
0.55	GO:0048747	muscle fiber development
0.55	GO:0006941	striated muscle contraction
0.54	GO:0030308	negative regulation of cell growth
0.52	GO:0009791	post-embryonic development
0.36	GO:0061049	cell growth involved in cardiac muscle cell development

0.69	GO:0005509	calcium ion binding
0.55	GO:0003785	actin monomer binding
0.35	GO:0032036	myosin heavy chain binding
0.35	GO:0008307	structural constituent of muscle

0.57	GO:0097512	cardiac myofibril
0.51	GO:0015629	actin cytoskeleton
0.40	GO:0031672	A band
0.38	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.35	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q8WNN6|SODC_CANLF
Superoxide dismutase [Cu-Zn]
Search

SOD1

0.54	Superoxide dismutase [Cu-Zn]

0.75	GO:0006801	superoxide metabolic process
0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.69	GO:0098869	cellular oxidant detoxification
0.58	GO:0045541	negative regulation of cholesterol biosynthetic process
0.57	GO:0060087	relaxation of vascular smooth muscle
0.57	GO:0050665	hydrogen peroxide biosynthetic process
0.57	GO:0060088	auditory receptor cell stereocilium organization
0.56	GO:0032287	peripheral nervous system myelin maintenance
0.56	GO:0060052	neurofilament cytoskeleton organization

0.77	GO:0004784	superoxide dismutase activity
0.58	GO:0030346	protein phosphatase 2B binding
0.54	GO:0046872	metal ion binding
0.52	GO:0048365	Rac GTPase binding
0.51	GO:0051087	chaperone binding
0.48	GO:0042802	identical protein binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0004842	ubiquitin-protein transferase activity

0.57	GO:0032839	dendrite cytoplasm
0.53	GO:0043025	neuronal cell body
0.52	GO:1904115	axon cytoplasm
0.51	GO:0005615	extracellular space
0.50	GO:0043209	myelin sheath
0.50	GO:0031012	extracellular matrix
0.49	GO:0031410	cytoplasmic vesicle
0.49	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.46	GO:0005654	nucleoplasm

0.77	EC:1.15.1.1	GO:0004784
0.34	KEGG:R03876	GO:0004842

sp|Q8WNW0|CP21A_CANLF
Steroid 21-hydroxylase
Search

CYP21A2

0.97	Mutant 21-hydroxylase B

0.53	GO:0055114	oxidation-reduction process
0.44	GO:0006694	steroid biosynthetic process
0.39	GO:0008212	mineralocorticoid metabolic process
0.37	GO:0042446	hormone biosynthetic process
0.36	GO:0008211	glucocorticoid metabolic process
0.36	GO:0042448	progesterone metabolic process
0.35	GO:0006956	complement activation
0.35	GO:0071375	cellular response to peptide hormone stimulus
0.35	GO:0016125	sterol metabolic process
0.35	GO:0006954	inflammatory response

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0005496	steroid binding
0.34	GO:0004866	endopeptidase inhibitor activity

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.68