Queries 6001 to 7000

GO:0004177

tr|Q8SWX6|Q8SWX6_DROME
GH08893p
Search

0.37	thioredoxin domain-containing protein isoform X1

0.64	GO:0045454	cell redox homeostasis
0.40	GO:0043277	apoptotic cell clearance
0.40	GO:0034976	response to endoplasmic reticulum stress
0.38	GO:0006457	protein folding
0.33	GO:0007017	microtubule-based process

0.43	GO:0016853	isomerase activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0003676	nucleic acid binding

0.39	GO:0012505	endomembrane system
0.37	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0044444	cytoplasmic part
0.36	GO:0019866	organelle inner membrane
0.34	GO:0005869	dynactin complex
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0016853

tr|Q8SWZ1|Q8SWZ1_DROME
RH55021p
Search

0.69	Cys-loop ligand-gated ion channel subunit

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.52	GO:1904456	negative regulation of neuronal action potential
0.51	GO:0060012	synaptic transmission, glycinergic
0.48	GO:0042752	regulation of circadian rhythm
0.38	GO:0006821	chloride transport

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity
0.38	GO:0005254	chloride channel activity
0.37	GO:0099095	ligand-gated anion channel activity

0.55	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8SWZ6|Q8SWZ6_DROME
RH51312p
Search

0.88	Fas apoptotic inhibitory molecule a

0.78	GO:0043066	negative regulation of apoptotic process
0.36	GO:0000387	spliceosomal snRNP assembly
0.34	GO:0006915	apoptotic process
0.33	GO:0006468	protein phosphorylation
0.33	GO:0015031	protein transport

0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0046872	metal ion binding

0.36	GO:0005681	spliceosomal complex
0.32	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.32

EC:2.3

GO:0016746

tr|Q8SX06|Q8SX06_DROME
GEO08318p1
Search

0.56	immunoglobulin domain-containing protein oig-1

0.41	GO:0006508	proteolysis
0.39	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0006468	protein phosphorylation
0.38	GO:0006979	response to oxidative stress
0.37	GO:0098869	cellular oxidant detoxification
0.35	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0055114	oxidation-reduction process

0.42	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0004930	G-protein coupled receptor activity
0.38	GO:0004601	peroxidase activity
0.38	GO:0016787	hydrolase activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0016301	kinase activity
0.36	GO:0020037	heme binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0008144	drug binding

0.30

GO:0016020

membrane

0.38	EC:1.11.1.7	GO:0004601
0.38	KEGG:R03532	GO:0004601

tr|Q8SX21|Q8SX21_DROME
HIF prolyl hydroxylase, isoform C
Search

EGLN1

0.95	Hypoxia-inducible factor prolyl hydroxylase 2

0.60	GO:0019511	peptidyl-proline hydroxylation
0.58	GO:0001666	response to hypoxia
0.54	GO:0019471	4-hydroxyproline metabolic process
0.53	GO:0006611	protein export from nucleus
0.53	GO:0036294	cellular response to decreased oxygen levels
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0030307	positive regulation of cell growth
0.52	GO:0032364	oxygen homeostasis
0.51	GO:0060347	heart trabecula formation
0.51	GO:0071731	response to nitric oxide

0.79	GO:0031418	L-ascorbic acid binding
0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.62	GO:0005506	iron ion binding
0.52	GO:0051213	dioxygenase activity
0.45	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0008270	zinc ion binding
0.34	GO:0019826	oxygen sensor activity
0.34	GO:0019899	enzyme binding

0.47	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.33	GO:0000145	exocyst

0.68

GO:0016705

tr|Q8SX23|Q8SX23_DROME
RE67967p
Search

0.62	GO:0032504	multicellular organism reproduction
0.48	GO:0001558	regulation of cell growth

0.50

GO:0005520

insulin-like growth factor binding

0.43	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|Q8SX24|Q8SX24_DROME
RE67941p
Search

0.80	Coiled-coil domain-containing protein 76

0.66	GO:0008033	tRNA processing
0.63	GO:0032259	methylation
0.41	GO:0009451	RNA modification
0.36	GO:0044260	cellular macromolecule metabolic process
0.33	GO:0006520	cellular amino acid metabolic process

0.63	GO:0008168	methyltransferase activity
0.41	GO:0140101	catalytic activity, acting on a tRNA
0.35	GO:0004046	aminoacylase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0016853	isomerase activity

0.34	GO:0005730	nucleolus
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0008168

tr|Q8SX25|Q8SX25_DROME
CG1463, isoform A
Search

0.76	Zinc finger HIT domain-containing protein 6

0.35	GO:0048254	snoRNA localization
0.35	GO:0097359	UDP-glucosylation
0.35	GO:0000492	box C/D snoRNP assembly
0.34	GO:0006486	protein glycosylation
0.34	GO:0098655	cation transmembrane transport
0.34	GO:0051259	protein oligomerization

0.54	GO:0046872	metal ion binding
0.35	GO:0001094	TFIID-class transcription factor binding
0.35	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity
0.34	GO:0051117	ATPase binding
0.34	GO:0008324	cation transmembrane transporter activity
0.34	GO:0042802	identical protein binding
0.32	GO:0003676	nucleic acid binding

0.35	GO:0070761	pre-snoRNP complex
0.30	GO:0016020	membrane

0.35

GO:0003980

tr|Q8SX32|Q8SX32_DROME
Arginine methyltransferase 8
Search

0.36	Arginine n-methyltransferase

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.51	GO:0018195	peptidyl-arginine modification
0.48	GO:0016570	histone modification
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0090398	cellular senescence
0.35	GO:0016049	cell growth
0.34	GO:0042254	ribosome biogenesis

0.63	GO:0008168	methyltransferase activity
0.42	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0005515	protein binding
0.35	GO:0043022	ribosome binding
0.34	GO:0003682	chromatin binding
0.34	GO:0016301	kinase activity
0.34	GO:0004649	poly(ADP-ribose) glycohydrolase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0008565	protein transporter activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.42	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.34	GO:0015935	small ribosomal subunit
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.63

GO:0008168

tr|Q8SX35|Q8SX35_DROME
GEO07743p1
Search

RNF11

0.45	RING finger protein 11

0.73	GO:0051865	protein autoubiquitination
0.70	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.61	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.37	GO:0046856	phosphatidylinositol dephosphorylation

0.68	GO:0004842	ubiquitin-protein transferase activity
0.60	GO:0061659	ubiquitin-like protein ligase activity
0.44	GO:0016874	ligase activity
0.41	GO:0008270	zinc ion binding
0.38	GO:0005515	protein binding
0.34	GO:0003677	DNA binding
0.33	GO:0016787	hydrolase activity

0.66	GO:0000151	ubiquitin ligase complex
0.45	GO:0055037	recycling endosome
0.44	GO:0005769	early endosome
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome

0.44	EC:6	GO:0016874
0.68	KEGG:R03876	GO:0004842

tr|Q8SX37|Q8SX37_DROME
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Search

0.69	CDP-diacylglycerol--inositol 3-phosphatidyltransferase

0.68	GO:0008654	phospholipid biosynthetic process
0.50	GO:0071711	basement membrane organization
0.47	GO:0046488	phosphatidylinositol metabolic process
0.47	GO:0007602	phototransduction
0.47	GO:0045017	glycerolipid biosynthetic process
0.38	GO:0071788	endoplasmic reticulum tubular network maintenance
0.37	GO:0072576	liver morphogenesis
0.37	GO:0060729	intestinal epithelial structure maintenance
0.37	GO:0060219	camera-type eye photoreceptor cell differentiation
0.37	GO:0010842	retina layer formation

0.81	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity
0.36	GO:0019992	diacylglycerol binding
0.35	GO:0043178	alcohol binding
0.35	GO:0017171	serine hydrolase activity
0.34	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.34	GO:0030145	manganese ion binding
0.34	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.67	GO:0005794	Golgi apparatus
0.39	GO:0005741	mitochondrial outer membrane
0.34	GO:0019866	organelle inner membrane
0.33	GO:0012510	trans-Golgi network transport vesicle membrane
0.33	GO:0030132	clathrin coat of coated pit
0.33	GO:0030125	clathrin vesicle coat
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.81	EC:2.7.8.11	GO:0003881
0.81	KEGG:R01802	GO:0003881

tr|Q8SX38|Q8SX38_DROME
RE27552p
Search

DUSP11

0.50	Tyrosine-protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.49	GO:0098507	polynucleotide 5' dephosphorylation
0.39	GO:0016070	RNA metabolic process
0.33	GO:0006413	translational initiation

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.49	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides
0.49	GO:0004651	polynucleotide 5'-phosphatase activity
0.40	GO:0003723	RNA binding
0.35	GO:0016779	nucleotidyltransferase activity

0.49	GO:0045171	intercellular bridge
0.48	GO:0001650	fibrillar center
0.47	GO:0016607	nuclear speck
0.33	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.1.3

GO:0008138

tr|Q8SX40|Q8SX40_DROME
RE19693p
Search

0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.38	GO:0061332	Malpighian tubule bud morphogenesis
0.38	GO:0007400	neuroblast fate determination
0.38	GO:0035206	regulation of hemocyte proliferation
0.37	GO:0048749	compound eye development
0.36	GO:0007411	axon guidance
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0006325	chromatin organization

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003682	chromatin binding
0.32	GO:0005515	protein binding
0.32	GO:0004672	protein kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005634	nucleus
0.33	GO:0032133	chromosome passenger complex
0.32	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

tr|Q8SX44|Q8SX44_DROME
RE11703p
Search

0.73	F-box/WD repeat-containing protein 4

0.75	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.49	GO:0006468	protein phosphorylation

0.50	GO:0004672	protein kinase activity
0.44	GO:0030554	adenyl nucleotide binding
0.44	GO:0097367	carbohydrate derivative binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding

0.74

GO:0019005

SCF ubiquitin ligase complex

tr|Q8SX47|Q8SX47_DROME
RE06583p
Search

0.31	Inactive hydroxysteroid dehydrogenase protein 1

0.47	GO:0007030	Golgi organization
0.47	GO:0055114	oxidation-reduction process
0.46	GO:0008285	negative regulation of cell proliferation
0.45	GO:0030497	fatty acid elongation
0.35	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0006702	androgen biosynthetic process
0.34	GO:0061370	testosterone biosynthetic process
0.34	GO:0000056	ribosomal small subunit export from nucleus
0.34	GO:0030539	male genitalia development
0.34	GO:0000055	ribosomal large subunit export from nucleus

0.48	GO:0016491	oxidoreductase activity
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0050661	NADP binding
0.34	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0017056	structural constituent of nuclear pore
0.33	GO:0004012	phospholipid-translocating ATPase activity
0.33	GO:0005216	ion channel activity
0.33	GO:0016831	carboxy-lyase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0000287	magnesium ion binding

0.47	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.33	GO:0044431	Golgi apparatus part
0.30	GO:0016021	integral component of membrane

0.48

GO:0016491

tr|Q8SX54|Q8SX54_DROME
CG3505
Search

0.30	serine protease easter

0.61	GO:0006508	proteolysis
0.40	GO:0009620	response to fungus
0.40	GO:0035006	melanization defense response
0.38	GO:0002816	regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
0.37	GO:0002804	positive regulation of antifungal peptide production
0.37	GO:0045752	positive regulation of Toll signaling pathway
0.37	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.37	GO:0008063	Toll signaling pathway
0.37	GO:0050830	defense response to Gram-positive bacterium
0.36	GO:0050829	defense response to Gram-negative bacterium

0.69	GO:0004252	serine-type endopeptidase activity
0.32	GO:0005509	calcium ion binding
0.31	GO:0016301	kinase activity
0.31	GO:0003676	nucleic acid binding

0.36	GO:0005576	extracellular region
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004252

tr|Q8SX57|Q8SX57_DROME
LD44221p
Search

0.26	Short-chain dehydrogenease/reductase

0.52

GO:0055114

oxidation-reduction process

0.53	GO:0016491	oxidoreductase activity
0.34	GO:0004312	fatty acid synthase activity
0.32	GO:0003677	DNA binding

0.53

GO:0016491

sp|Q8SX68|Y0915_DROME
Uncharacterized protein CG10915
Search

0.11	CTTNBP2 N-terminal protein (Fragment)

0.42

GO:0006030

chitin metabolic process

0.42	GO:0008061	chitin binding
0.40	GO:0016887	ATPase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0032553	ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0016887

tr|Q8SX76|Q8SX76_DROME
LD24646p
Search

0.78	Pachytene checkpoint protein 2

0.55	GO:1903046	meiotic cell cycle process
0.50	GO:0045835	negative regulation of meiotic nuclear division
0.48	GO:0000280	nuclear division
0.47	GO:0000075	cell cycle checkpoint
0.47	GO:0035825	homologous recombination
0.46	GO:0098813	nuclear chromosome segregation
0.43	GO:0051276	chromosome organization
0.41	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:0051013	microtubule severing
0.34	GO:0001556	oocyte maturation

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008568	microtubule-severing ATPase activity
0.33	GO:0005515	protein binding
0.33	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.44	GO:0005694	chromosome
0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.36

EC:3.6.4.3

GO:0008568

tr|Q8SX78|Q8SX78_DROME
LD05679p
Search

0.70	Lipoyltransferase mitochondrial

0.77	GO:0009249	protein lipoylation
0.37	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c

0.46	GO:0016874	ligase activity
0.40	GO:0016740	transferase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0140096	catalytic activity, acting on a protein

0.39	GO:0005750	mitochondrial respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.46

GO:0016874

tr|Q8SX81|Q8SX81_DROME
LD20292p
Search

0.72	GO:0097352	autophagosome maturation
0.69	GO:0007041	lysosomal transport
0.65	GO:0009267	cellular response to starvation
0.60	GO:0016192	vesicle-mediated transport
0.60	GO:0046907	intracellular transport
0.57	GO:0034613	cellular protein localization
0.55	GO:0015031	protein transport
0.50	GO:0035542	regulation of SNARE complex assembly
0.49	GO:0007032	endosome organization
0.49	GO:0007040	lysosome organization

0.48	GO:0030674	protein binding, bridging
0.44	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0008270	zinc ion binding

0.72	GO:0030897	HOPS complex
0.50	GO:0033263	CORVET complex
0.30	GO:0016021	integral component of membrane

0.44

GO:0004842

sp|Q8SX83|SPEN_DROME
Protein split ends
Search

0.71	GO:0048106	establishment of thoracic bristle planar orientation
0.69	GO:0035321	maintenance of imaginal disc-derived wing hair orientation
0.68	GO:0007403	glial cell fate determination
0.67	GO:0007400	neuroblast fate determination
0.66	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.65	GO:0007379	segment specification
0.65	GO:0035222	wing disc pattern formation
0.64	GO:0007173	epidermal growth factor receptor signaling pathway
0.63	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.63	GO:0007422	peripheral nervous system development

0.59	GO:0003723	RNA binding
0.32	GO:0033904	dextranase activity

0.49	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:3.2.1.11

GO:0033904

sp|Q8SX86|NUTC_DROME
Protein nutcracker
Search

0.85	GO:0007291	sperm individualization
0.84	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.79	GO:0050821	protein stabilization
0.61	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.54	GO:0016567	protein ubiquitination
0.40	GO:0031532	actin cytoskeleton reorganization

0.55	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0005515	protein binding

0.82	GO:0019005	SCF ubiquitin ligase complex
0.41	GO:0005737	cytoplasm
0.37	GO:0005634	nucleus

0.55

GO:0004842

tr|Q8SX87|Q8SX87_DROME
Atf6, isoform C
Search

0.83	GO:0030968	endoplasmic reticulum unfolded protein response
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.64	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:0043620	regulation of DNA-templated transcription in response to stress
0.39	GO:0001666	response to hypoxia
0.36	GO:0001654	eye development
0.36	GO:0043065	positive regulation of apoptotic process
0.36	GO:0007601	visual perception

0.85	GO:0035497	cAMP response element binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0042802	identical protein binding
0.44	GO:0046983	protein dimerization activity
0.38	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding

0.67	GO:0012505	endomembrane system
0.61	GO:0005634	nucleus
0.60	GO:0031984	organelle subcompartment
0.49	GO:0044444	cytoplasmic part
0.37	GO:0005667	transcription factor complex
0.36	GO:0032993	protein-DNA complex
0.36	GO:0043233	organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SX89|Q8SX89_DROME
Kugelkern, isoform A
Search

0.64	Kugelkern, isoform A

0.85	GO:0007349	cellularization
0.84	GO:0008344	adult locomotory behavior
0.83	GO:0016331	morphogenesis of embryonic epithelium
0.83	GO:0007569	cell aging
0.82	GO:0006997	nucleus organization
0.33	GO:0022900	electron transport chain
0.33	GO:0055085	transmembrane transport

0.83	GO:0005637	nuclear inner membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SX97|Q8SX97_DROME
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Search

0.48	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.39	GO:0009061	anaerobic respiration
0.36	GO:0019637	organophosphate metabolic process
0.36	GO:0006796	phosphate-containing compound metabolic process
0.36	GO:0072521	purine-containing compound metabolic process
0.35	GO:0008610	lipid biosynthetic process
0.35	GO:0017144	drug metabolic process
0.35	GO:0044255	cellular lipid metabolic process
0.35	GO:0055086	nucleobase-containing small molecule metabolic process

0.77	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.38	GO:0004609	phosphatidylserine decarboxylase activity
0.36	GO:0009055	electron transfer activity
0.33	GO:0004177	aminopeptidase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0016874	ligase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.56	GO:0031966	mitochondrial membrane
0.56	GO:0019866	organelle inner membrane
0.42	GO:0005886	plasma membrane
0.41	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.41	GO:0045283	fumarate reductase complex
0.38	GO:0098798	mitochondrial protein complex
0.34	GO:0031301	integral component of organelle membrane

0.77	EC:1.3.5.1	GO:0008177
0.77	KEGG:R02164	GO:0008177

tr|Q8SXB0|Q8SXB0_DROME
ADAM metallopeptidase with thrombospondin type 1 motif A, isoform B
Search

0.71	A disintegrin and metalloproteinase with thrombospondin motifs 9

0.61	GO:0006508	proteolysis
0.61	GO:0007436	larval salivary gland morphogenesis
0.60	GO:0007280	pole cell migration
0.60	GO:0007427	epithelial cell migration, open tracheal system
0.59	GO:0008078	mesodermal cell migration
0.58	GO:0007229	integrin-mediated signaling pathway
0.55	GO:0030198	extracellular matrix organization
0.43	GO:1990798	pancreas regeneration
0.41	GO:0031018	endocrine pancreas development
0.35	GO:0090673	endothelial cell-matrix adhesion

0.70	GO:0004222	metalloendopeptidase activity
0.61	GO:0008270	zinc ion binding
0.35	GO:0002020	protease binding
0.34	GO:0009673	low-affinity phosphate transmembrane transporter activity
0.33	GO:0005178	integrin binding
0.33	GO:0008201	heparin binding

0.64	GO:0005576	extracellular region
0.35	GO:0016607	nuclear speck
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.70

GO:0004222

tr|Q8SXB3|Q8SXB3_DROME
GH12334p
Search

0.44	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

0.49	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.45	GO:0017001	antibiotic catabolic process
0.45	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0019878	lysine biosynthetic process via aminoadipic acid
0.38	GO:0021682	nerve maturation
0.38	GO:0072553	terminal button organization
0.38	GO:0060857	establishment of glial blood-brain barrier
0.38	GO:0061343	cell adhesion involved in heart morphogenesis
0.38	GO:0097105	presynaptic membrane assembly
0.37	GO:0019991	septate junction assembly

0.78	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.64	GO:0000287	magnesium ion binding
0.50	GO:0000213	tRNA-intron endonuclease activity
0.45	GO:0008800	beta-lactamase activity
0.40	GO:0008270	zinc ion binding
0.38	GO:0003676	nucleic acid binding

0.38	GO:0005919	pleated septate junction
0.37	GO:0048786	presynaptic active zone
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:2.7.8.7

GO:0008897

tr|Q8SXC0|Q8SXC0_DROME
CG5577, isoform A
Search

0.29	Phosphoglycolate phosphatase

0.64	GO:0016311	dephosphorylation
0.38	GO:0006464	cellular protein modification process
0.33	GO:0016310	phosphorylation

0.65	GO:0016791	phosphatase activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0016301	kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.35	GO:0005615	extracellular space

0.65

GO:0016791

tr|Q8SXC2|Q8SXC2_DROME
CG6950, isoform A
Search

0.78	Kynurenine--oxoglutarate transaminase

0.59	GO:0097052	L-kynurenine metabolic process
0.49	GO:0009058	biosynthetic process
0.42	GO:0006575	cellular modified amino acid metabolic process
0.35	GO:0006103	2-oxoglutarate metabolic process

0.67	GO:0030170	pyridoxal phosphate binding
0.63	GO:0036137	kynurenine aminotransferase activity
0.50	GO:0047804	cysteine-S-conjugate beta-lyase activity
0.46	GO:0070548	L-glutamine aminotransferase activity
0.35	GO:0042803	protein homodimerization activity

0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.50

EC:4.4.1.13

GO:0047804

tr|Q8SXC9|Q8SXC9_DROME
GH05933p
Search

0.49	pyridoxal phosphate phosphatase

0.65	GO:0016311	dephosphorylation
0.38	GO:0006464	cellular protein modification process
0.34	GO:0044262	cellular carbohydrate metabolic process

0.66	GO:0016791	phosphatase activity
0.37	GO:0140096	catalytic activity, acting on a protein

0.39	GO:0005829	cytosol
0.36	GO:0005634	nucleus

0.66

GO:0016791

tr|Q8SXD1|Q8SXD1_DROME
Elongation of very long chain fatty acids protein
Search

0.48	Elongation of very long chain fatty acids protein (Fragment)

0.70	GO:0006633	fatty acid biosynthetic process
0.45	GO:0000038	very long-chain fatty acid metabolic process
0.42	GO:0030148	sphingolipid biosynthetic process
0.39	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.38	GO:0033559	unsaturated fatty acid metabolic process
0.34	GO:0006270	DNA replication initiation

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.46	GO:0009922	fatty acid elongase activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.3.1.199

GO:0102338

sp|Q8SXD4|MIDN_DROME
Midnolin homolog
Search

0.11	Midnolin homolog

0.81	GO:0010499	proteasomal ubiquitin-independent protein catabolic process
0.36	GO:0032259	methylation
0.35	GO:0033132	negative regulation of glucokinase activity
0.34	GO:0000128	flocculation
0.34	GO:0046676	negative regulation of insulin secretion
0.33	GO:0061088	regulation of sequestering of zinc ion
0.33	GO:0010043	response to zinc ion
0.33	GO:0071577	zinc II ion transmembrane transport
0.32	GO:0023014	signal transduction by protein phosphorylation
0.32	GO:0000160	phosphorelay signal transduction system

0.36	GO:0008168	methyltransferase activity
0.34	GO:0019900	kinase binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005385	zinc ion transmembrane transporter activity
0.32	GO:0000155	phosphorelay sensor kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.38	GO:0005829	cytosol
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008168

tr|Q8SXE1|Q8SXE1_DROME
RH69521p
Search

CFB

0.45	CLIP-domain serine protease

0.61	GO:0006508	proteolysis
0.35	GO:0007597	blood coagulation, intrinsic pathway
0.35	GO:0009058	biosynthetic process
0.34	GO:0035235	ionotropic glutamate receptor signaling pathway
0.34	GO:0051919	positive regulation of fibrinolysis
0.33	GO:0001867	complement activation, lectin pathway
0.33	GO:0006958	complement activation, classical pathway
0.33	GO:0006629	lipid metabolic process
0.33	GO:0051604	protein maturation

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004970	ionotropic glutamate receptor activity
0.33	GO:0008081	phosphoric diester hydrolase activity
0.33	GO:0004180	carboxypeptidase activity
0.32	GO:0005509	calcium ion binding

0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.69

GO:0004252

tr|Q8SXF0|Q8SXF0_DROME
Mitochondrial ribosomal protein S9
Search

0.81	Mitochondrial ribosomal protein S9

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.41	GO:0042274	ribosomal small subunit biogenesis
0.40	GO:0016072	rRNA metabolic process
0.35	GO:0034220	ion transmembrane transport
0.34	GO:0042769	DNA damage response, detection of DNA damage
0.33	GO:0043624	cellular protein complex disassembly
0.33	GO:0043039	tRNA aminoacylation

0.63	GO:0003735	structural constituent of ribosome
0.38	GO:0003723	RNA binding
0.37	GO:0005216	ion channel activity
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.43	GO:0005730	nucleolus
0.41	GO:0005759	mitochondrial matrix
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:6.1

GO:0016875

tr|Q8SXF2|Q8SXF2_DROME
CG5612
Search

tr|Q8SXG2|Q8SXG2_DROME
CG32711-PA long isoform
Search

0.44	GO:0005102	receptor binding
0.37	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.37	GO:0140101	catalytic activity, acting on a tRNA
0.37	GO:0019843	rRNA binding
0.36	GO:0016829	lyase activity

0.73	GO:0005703	polytene chromosome puff
0.73	GO:0005705	polytene chromosome interband
0.36	GO:0005634	nucleus
0.36	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:6.1

GO:0016875

tr|Q8SXG7|Q8SXG7_DROME
RE72132p
Search

0.37	tRNA selenocysteine 1-associated protein 1

0.33	GO:0034605	cellular response to heat
0.32	GO:0006397	mRNA processing

0.59

GO:0003723

RNA binding

0.33	GO:0031011	Ino80 complex
0.33	GO:0010494	cytoplasmic stress granule
0.32	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SXG9|Q8SXG9_DROME
RE65335p
Search

0.10	cell wall protein DAN4

0.53	GO:0006030	chitin metabolic process
0.40	GO:0032501	multicellular organismal process
0.39	GO:0051930	regulation of sensory perception of pain
0.38	GO:0010466	negative regulation of peptidase activity
0.38	GO:0019538	protein metabolic process
0.38	GO:0005975	carbohydrate metabolic process
0.38	GO:0060249	anatomical structure homeostasis
0.37	GO:2000683	regulation of cellular response to X-ray
0.37	GO:0052548	regulation of endopeptidase activity
0.37	GO:0065004	protein-DNA complex assembly

0.53	GO:0008061	chitin binding
0.39	GO:0030247	polysaccharide binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0030414	peptidase inhibitor activity
0.38	GO:0005509	calcium ion binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0004568	chitinase activity
0.37	GO:0061135	endopeptidase regulator activity
0.37	GO:0017171	serine hydrolase activity
0.37	GO:0016301	kinase activity

0.51	GO:0005576	extracellular region
0.35	GO:0000124	SAGA complex
0.35	GO:0005669	transcription factor TFIID complex
0.35	GO:0000786	nucleosome
0.35	GO:0031410	cytoplasmic vesicle
0.30	GO:0016020	membrane

0.38

GO:0016773

tr|Q8SXH1|Q8SXH1_DROME
RE54320p
Search

0.48	GO:0006030	chitin metabolic process
0.41	GO:0005975	carbohydrate metabolic process

0.48	GO:0016787	hydrolase activity
0.47	GO:0008061	chitin binding

0.78	GO:0070701	mucus layer
0.46	GO:0005615	extracellular space
0.43	GO:0046695	SLIK (SAGA-like) complex
0.43	GO:0000124	SAGA complex
0.42	GO:0005669	transcription factor TFIID complex
0.30	GO:0031224	intrinsic component of membrane

0.48

GO:0016787

tr|Q8SXH7|Q8SXH7_DROME
GEO09915p1
Search

0.54	Protein with signal anchor

0.39	GO:0006420	arginyl-tRNA aminoacylation
0.37	GO:0016579	protein deubiquitination
0.36	GO:0006511	ubiquitin-dependent protein catabolic process

0.39	GO:0004814	arginine-tRNA ligase activity
0.37	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.39

EC:6.1.1.19

GO:0004814

tr|Q8SXI2|Q8SXI2_DROME
RE36623p
Search

0.11	craniofacial development protein 1

0.85	GO:0010032	meiotic chromosome condensation
0.85	GO:2000615	regulation of histone H3-K9 acetylation
0.84	GO:0051570	regulation of histone H3-K9 methylation
0.84	GO:0051569	regulation of histone H3-K4 methylation
0.80	GO:0007076	mitotic chromosome condensation
0.40	GO:0016569	covalent chromatin modification
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.83	GO:0019894	kinesin binding
0.39	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.36	GO:0005506	iron ion binding

0.82	GO:0005700	polytene chromosome
0.60	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39

EC:1.13.11

GO:0016702

tr|Q8SXK0|Q8SXK0_DROME
RE18748p
Search

0.80	mTERF domain-containing protein 2

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0042255	ribosome assembly
0.39	GO:0008380	RNA splicing
0.38	GO:0006886	intracellular protein transport
0.38	GO:0032502	developmental process

0.72	GO:0003690	double-stranded DNA binding
0.40	GO:0003727	single-stranded RNA binding
0.37	GO:0019843	rRNA binding

0.33

GO:0005622

intracellular

tr|Q8SXK2|Q8SXK2_DROME
RE18459p
Search

0.41	Mitochondrial arginyl-tRNA synthetase

0.77	GO:0006420	arginyl-tRNA aminoacylation
0.39	GO:0032543	mitochondrial translation
0.33	GO:0048268	clathrin coat assembly
0.33	GO:0008299	isoprenoid biosynthetic process

0.78	GO:0004814	arginine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003735	structural constituent of ribosome
0.34	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0004826	phenylalanine-tRNA ligase activity
0.34	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.33	GO:0005545	1-phosphatidylinositol binding
0.33	GO:0030276	clathrin binding

0.43	GO:0005737	cytoplasm
0.40	GO:0043227	membrane-bounded organelle
0.40	GO:0043229	intracellular organelle
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.78	EC:6.1.1.19	GO:0004814
0.34	KEGG:R01978	GO:0004421

sp|Q8SXL2|CCHA2_DROME
Neuropeptide CCHamide-2
Search

0.81	Neuropeptide CCHamide-2

0.80	GO:0007218	neuropeptide signaling pathway
0.75	GO:0010469	regulation of receptor activity

0.84

GO:0005184

neuropeptide hormone activity

0.59	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

tr|Q8SXL5|Q8SXL5_DROME
RE09177p
Search

0.79	Peritrophin-48

0.78

GO:0006030

chitin metabolic process

0.77

GO:0008061

chitin binding

0.66

GO:0005576

extracellular region

tr|Q8SXP0|Q8SXP0_DROME
GH19076p
Search

0.65	Phosphatidate phosphatase LPIN3

0.86	GO:0007474	imaginal disc-derived wing vein specification
0.85	GO:0030514	negative regulation of BMP signaling pathway
0.82	GO:0019217	regulation of fatty acid metabolic process
0.82	GO:0055088	lipid homeostasis
0.82	GO:0019432	triglyceride biosynthetic process
0.78	GO:0042594	response to starvation
0.55	GO:0016311	dephosphorylation
0.42	GO:0009062	fatty acid catabolic process
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II

0.67	GO:0008195	phosphatidate phosphatase activity
0.62	GO:0003713	transcription coactivator activity

0.88	GO:0035183	female germline ring canal inner rim
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.67

EC:3.1.3.4

GO:0008195

tr|Q8SXP1|Q8SXP1_DROME
GH14656p
Search

0.30

GO:0044425

membrane part

tr|Q8SXP8|Q8SXP8_DROME
GH09868p
Search

0.72	RNA-binding protein musashi

0.48	GO:0072553	terminal button organization
0.48	GO:2000331	regulation of terminal button organization
0.48	GO:0008345	larval locomotory behavior
0.48	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.47	GO:0033119	negative regulation of RNA splicing
0.47	GO:0007628	adult walking behavior
0.47	GO:1900006	positive regulation of dendrite development
0.47	GO:0007274	neuromuscular synaptic transmission
0.47	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway
0.46	GO:0007528	neuromuscular junction development

0.59	GO:0003723	RNA binding
0.47	GO:0003677	DNA binding

0.49	GO:0031673	H zone
0.45	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005634	nucleus

tr|Q8SXQ1|Q8SXQ1_DROME
CG9629
Search

0.35	Alpha-aminoadipic semialdehyde dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0042426	choline catabolic process
0.34	GO:0006081	cellular aldehyde metabolic process
0.34	GO:0007605	sensory perception of sound
0.34	GO:0019285	glycine betaine biosynthetic process from choline
0.34	GO:0009269	response to desiccation
0.34	GO:0009737	response to abscisic acid
0.34	GO:0006554	lysine catabolic process
0.34	GO:0009651	response to salt stress
0.33	GO:0006886	intracellular protein transport

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0070003	threonine-type peptidase activity
0.33	GO:0005198	structural molecule activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0004175	endopeptidase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.37	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.35	GO:0031982	vesicle
0.34	GO:0030132	clathrin coat of coated pit
0.34	GO:0043230	extracellular organelle
0.33	GO:0044431	Golgi apparatus part
0.33	GO:0005615	extracellular space
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0005839	proteasome core complex
0.33	GO:0031974	membrane-enclosed lumen

0.69

EC:1.2.1

GO:0016620

tr|Q8SXQ5|Q8SXQ5_DROME
RH03087p
Search

0.47	Glutaredoxin

0.69	GO:0045454	cell redox homeostasis
0.61	GO:0022900	electron transport chain
0.45	GO:0009249	protein lipoylation
0.43	GO:0030097	hemopoiesis
0.41	GO:0031163	metallo-sulfur cluster assembly
0.39	GO:0006790	sulfur compound metabolic process
0.38	GO:0051188	cofactor biosynthetic process
0.34	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly
0.32	GO:0044281	small molecule metabolic process

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.65	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.51	GO:0046872	metal ion binding
0.35	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.34	GO:0001187	RNA polymerase I CORE element sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.44	GO:0005759	mitochondrial matrix
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.35	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.35

EC:1.2.1.27

GO:0004491

sp|Q8SXQ7|PGPLF_DROME
Peptidoglycan-recognition protein LF
Search

0.77	Peptidoglycan-recognition protein LF

0.74	GO:0009253	peptidoglycan catabolic process
0.63	GO:0006955	immune response
0.61	GO:0006952	defense response
0.57	GO:0046329	negative regulation of JNK cascade
0.55	GO:0008340	determination of adult lifespan
0.52	GO:0009617	response to bacterium
0.49	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0061059	positive regulation of peptidoglycan recognition protein signaling pathway
0.34	GO:0098581	detection of external biotic stimulus
0.33	GO:0010243	response to organonitrogen compound

0.76	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.65	GO:0042834	peptidoglycan binding
0.63	GO:0008270	zinc ion binding
0.33	GO:0005272	sodium channel activity

0.47	GO:0005887	integral component of plasma membrane
0.33	GO:0005615	extracellular space

0.76

GO:0008745

tr|Q8SXQ8|Q8SXQ8_DROME
RE72485p
Search

0.10	Ester hydrolase (Fragment)

0.34	GO:0032447	protein urmylation
0.34	GO:0034227	tRNA thio-modification
0.34	GO:0002098	tRNA wobble uridine modification
0.32	GO:0015074	DNA integration

0.42	GO:0008270	zinc ion binding
0.41	GO:0016787	hydrolase activity
0.33	GO:0000049	tRNA binding
0.33	GO:0016779	nucleotidyltransferase activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.35	GO:0070062	extracellular exosome
0.32	GO:0015630	microtubule cytoskeleton
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.41

GO:0016787

tr|Q8SXR4|Q8SXR4_DROME
RE54230p
Search

0.50	Nuclear transcription factor Tfp1

0.62	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0044719	regulation of imaginal disc-derived wing size
0.54	GO:0008039	synaptic target recognition
0.53	GO:0016203	muscle attachment

0.62	GO:0004930	G-protein coupled receptor activity
0.46	GO:0005509	calcium ion binding
0.41	GO:0016787	hydrolase activity

0.54	GO:0005927	muscle tendon junction
0.30	GO:0016020	membrane

0.41

GO:0016787

tr|Q8SXR5|Q8SXR5_DROME
CG8366
Search

EXO

0.37	Exonuclease

0.46

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.51

GO:0016787

hydrolase activity

0.51

GO:0016787

tr|Q8SXR7|Q8SXR7_DROME
CG3394, isoform A
Search

0.43	Very-long-chain acyl-CoA synthetase

0.40	GO:0015908	fatty acid transport
0.39	GO:0001676	long-chain fatty acid metabolic process
0.37	GO:0016192	vesicle-mediated transport
0.34	GO:0009253	peptidoglycan catabolic process

0.41	GO:0031957	very long-chain fatty acid-CoA ligase activity
0.39	GO:0004467	long-chain fatty acid-CoA ligase activity
0.34	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.33	GO:0008270	zinc ion binding

0.35	GO:0030008	TRAPP complex
0.30	GO:0016021	integral component of membrane

0.39

EC:6.2.1.3

GO:0004467

tr|Q8SXS0|Q8SXS0_DROME
CG7071, isoform A
Search

0.72	Endoplasmic reticulum-based factor for assembly of V-ATPase

0.84	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.36	GO:0030968	endoplasmic reticulum unfolded protein response
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II

0.36	GO:0035497	cAMP response element binding
0.36	GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity
0.34	GO:0003700	DNA binding transcription factor activity

0.45	GO:0031083	BLOC-1 complex
0.43	GO:0030133	transport vesicle
0.30	GO:0016020	membrane

0.36

EC:3.1.2.4

GO:0003860

tr|Q8SXS2|Q8SXS2_DROME
GEO07737p1
Search

0.30

GO:0044425

membrane part

tr|Q8SXS4|Q8SXS4_DROME
GEO07727p1
Search

0.30

GO:0044425

membrane part

tr|Q8SXS7|Q8SXS7_DROME
CG3734, isoform A
Search

0.53	thymus-specific serine protease

0.61

GO:0006508

proteolysis

0.67	GO:0008236	serine-type peptidase activity
0.41	GO:0008238	exopeptidase activity

0.30

GO:0016020

membrane

sp|Q8SXT3|HFW2_DROME
Protein singed wings 2
Search

0.91	Protein singed wings 2

0.52	GO:0035073	pupariation
0.51	GO:0035075	response to ecdysone
0.42	GO:0035556	intracellular signal transduction

0.36	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|Q8SXU0|Q8SXU0_DROME
RE22315p
Search

tr|Q8SXU3|Q8SXU3_DROME
CG8207
Search

0.41	GDP-mannose pyrophosphorylase Ab

0.49	GO:0009058	biosynthetic process
0.35	GO:0019673	GDP-mannose metabolic process
0.34	GO:0005991	trehalose metabolic process
0.33	GO:0006468	protein phosphorylation

0.63	GO:0016779	nucleotidyltransferase activity
0.34	GO:0005515	protein binding
0.34	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.35	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm
0.33	GO:0019028	viral capsid
0.30	GO:0016020	membrane

0.63

GO:0016779

tr|Q8SXV2|Q8SXV2_DROME
RE19849p
Search

0.30

GO:0044425

membrane part

tr|Q8SXV4|Q8SXV4_DROME
CG7296, isoform A
Search

0.67	glycine-rich protein 5

0.52	GO:0006413	translational initiation
0.47	GO:0032980	keratinocyte activation
0.45	GO:0051546	keratinocyte migration
0.45	GO:0045104	intermediate filament cytoskeleton organization
0.45	GO:0043616	keratinocyte proliferation
0.45	GO:0003334	keratinocyte development
0.44	GO:0031424	keratinization
0.43	GO:0018149	peptide cross-linking
0.41	GO:0097435	supramolecular fiber organization
0.40	GO:0006913	nucleocytoplasmic transport

0.52	GO:0003743	translation initiation factor activity
0.50	GO:0003924	GTPase activity
0.49	GO:0005525	GTP binding
0.46	GO:0005198	structural molecule activity
0.40	GO:0008092	cytoskeletal protein binding
0.36	GO:0097110	scaffold protein binding
0.34	GO:0030414	peptidase inhibitor activity
0.34	GO:0008312	7S RNA binding
0.34	GO:0031071	cysteine desulfurase activity
0.33	GO:0070279	vitamin B6 binding

0.55	GO:0005882	intermediate filament
0.44	GO:0001533	cornified envelope
0.42	GO:0005635	nuclear envelope
0.40	GO:0005737	cytoplasm
0.38	GO:0005654	nucleoplasm
0.37	GO:0043234	protein complex
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0005703	polytene chromosome puff
0.36	GO:0031984	organelle subcompartment
0.35	GO:0070062	extracellular exosome

0.34

EC:2.8.1.7

GO:0031071

tr|Q8SXV9|Q8SXV9_DROME
RH61745p
Search

0.10	keratin, type II cytoskeletal 68 kDa, component IB

0.52	GO:0006260	DNA replication
0.45	GO:0032784	regulation of DNA-templated transcription, elongation
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0001745	compound eye morphogenesis
0.42	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.41	GO:0006979	response to oxidative stress
0.41	GO:0098869	cellular oxidant detoxification
0.40	GO:0003006	developmental process involved in reproduction
0.40	GO:0006414	translational elongation
0.40	GO:0036099	female germ-line stem cell population maintenance

0.56	GO:0003697	single-stranded DNA binding
0.48	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.43	GO:0003723	RNA binding
0.42	GO:0004386	helicase activity
0.42	GO:0004601	peroxidase activity
0.39	GO:0020037	heme binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding

0.43	GO:0005703	polytene chromosome puff
0.42	GO:0005634	nucleus
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0000792	heterochromatin
0.37	GO:0019013	viral nucleocapsid
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0012505	endomembrane system
0.35	GO:0005581	collagen trimer
0.34	GO:0005737	cytoplasm
0.34	GO:0031984	organelle subcompartment

0.42	EC:1.11.1.7	GO:0004601
0.42	KEGG:R03532	GO:0004601

tr|Q8SXX0|Q8SXX0_DROME
RH08992p
Search

0.69	GO:0006364	rRNA processing
0.35	GO:0035556	intracellular signal transduction

0.33

GO:0046872

metal ion binding

0.32

GO:0005622

intracellular

tr|Q8SXX1|Q8SXX1_DROME
Phosphatidylinositol 5-phosphate 4-kinase, isoform A
Search

0.60	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.52	GO:1900186	negative regulation of clathrin-dependent endocytosis
0.49	GO:0040018	positive regulation of multicellular organism growth
0.48	GO:0030307	positive regulation of cell growth
0.47	GO:0032006	regulation of TOR signaling
0.43	GO:2000786	positive regulation of autophagosome assembly
0.43	GO:0035855	megakaryocyte development
0.39	GO:0048634	regulation of muscle organ development
0.34	GO:0006367	transcription initiation from RNA polymerase II promoter
0.33	GO:0005975	carbohydrate metabolic process

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004563	beta-N-acetylhexosaminidase activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.47	GO:0005769	early endosome
0.42	GO:0005776	autophagosome
0.39	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.82

GO:0016307

tr|Q8SXX2|Q8SXX2_DROME
Ance-3, isoform B
Search

0.66	Angiotensin-converting enzyme

0.61	GO:0006508	proteolysis
0.34	GO:1903597	negative regulation of gap junction assembly
0.34	GO:0071838	cell proliferation in bone marrow
0.34	GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation
0.34	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.34	GO:0003084	positive regulation of systemic arterial blood pressure
0.34	GO:1902033	regulation of hematopoietic stem cell proliferation
0.34	GO:0002446	neutrophil mediated immunity
0.34	GO:0061098	positive regulation of protein tyrosine kinase activity
0.34	GO:0043248	proteasome assembly

0.84	GO:0008241	peptidyl-dipeptidase activity
0.71	GO:0004180	carboxypeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.53	GO:0046872	metal ion binding

0.34	GO:0008541	proteasome regulatory particle, lid subcomplex
0.34	GO:0001669	acrosomal vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:3.4.15

GO:0008241

sp|Q8SXX4|CAPON_DROME
Capon-like protein
Search

0.73	Nitric oxide synthase 1 (neuronal) adaptor protein a

0.74	GO:0003062	regulation of heart rate by chemical signal
0.72	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.45	GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation
0.45	GO:0010750	positive regulation of nitric oxide mediated signal transduction
0.45	GO:1903947	positive regulation of ventricular cardiac muscle cell action potential
0.45	GO:1905033	positive regulation of membrane repolarization during cardiac muscle cell action potential
0.44	GO:1902261	positive regulation of delayed rectifier potassium channel activity
0.44	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
0.43	GO:0051000	positive regulation of nitric-oxide synthase activity
0.43	GO:1901841	regulation of high voltage-gated calcium channel activity

0.66	GO:0050998	nitric-oxide synthase binding
0.43	GO:0004672	protein kinase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003676	nucleic acid binding
0.37	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.64	GO:0030315	T-tubule
0.64	GO:0033017	sarcoplasmic reticulum membrane
0.62	GO:0005901	caveola
0.62	GO:0030018	Z disc
0.48	GO:0005739	mitochondrion
0.44	GO:1902937	inward rectifier potassium channel complex
0.41	GO:0005891	voltage-gated calcium channel complex
0.41	GO:0031965	nuclear membrane
0.41	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005829	cytosol

0.37

GO:0004553

tr|Q8SXX5|Q8SXX5_DROME
GEO12594p1
Search

0.37	transmembrane protein 203

0.36

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

0.37	GO:0004526	ribonuclease P activity
0.34	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.37

EC:3.1.26.5

GO:0004526

tr|Q8SXX8|Q8SXX8_DROME
RE67729p
Search

0.10	induced stolen tip protein TUB8

0.58	GO:0006413	translational initiation
0.41	GO:0051016	barbed-end actin filament capping
0.40	GO:0044718	siderophore transmembrane transport
0.40	GO:0051301	cell division
0.40	GO:0007049	cell cycle
0.39	GO:0032787	monocarboxylic acid metabolic process
0.39	GO:0007059	chromosome segregation
0.39	GO:0032505	reproduction of a single-celled organism
0.39	GO:0019954	asexual reproduction
0.38	GO:0018106	peptidyl-histidine phosphorylation

0.58	GO:0003743	translation initiation factor activity
0.55	GO:0003924	GTPase activity
0.54	GO:0032550	purine ribonucleoside binding
0.54	GO:0019001	guanyl nucleotide binding
0.47	GO:0032555	purine ribonucleotide binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042834	peptidoglycan binding
0.41	GO:0031992	energy transducer activity
0.40	GO:0015343	siderophore transmembrane transporter activity
0.40	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity

0.44	GO:0005737	cytoplasm
0.40	GO:0071944	cell periphery
0.39	GO:0015629	actin cytoskeleton
0.39	GO:1902494	catalytic complex
0.39	GO:0032153	cell division site
0.38	GO:0044430	cytoskeletal part
0.38	GO:0030288	outer membrane-bounded periplasmic space
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:2.3.1.12

GO:0004742

tr|Q8SXY2|Q8SXY2_DROME
Fatty acid 2-hydroxylase
Search

0.93	Fatty acid 2-hydroxylase

0.64	GO:0008610	lipid biosynthetic process
0.60	GO:0006631	fatty acid metabolic process
0.59	GO:0072330	monocarboxylic acid biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.42	GO:0001949	sebaceous gland cell differentiation
0.41	GO:0032286	central nervous system myelin maintenance
0.41	GO:0032287	peripheral nervous system myelin maintenance
0.40	GO:0042634	regulation of hair cycle
0.38	GO:0042127	regulation of cell proliferation
0.38	GO:0030258	lipid modification

0.76	GO:0080132	fatty acid alpha-hydroxylase activity
0.62	GO:0005506	iron ion binding
0.55	GO:0052722	fatty acid in-chain hydroxylase activity
0.53	GO:0020037	heme binding
0.35	GO:0030515	snoRNA binding
0.33	GO:0004601	peroxidase activity
0.33	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding

0.62	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.33	EC:1.11.1.7	GO:0004601
0.33	KEGG:R03532	GO:0004601

tr|Q8SXY5|Q8SXY5_DROME
RE54525p
Search

0.64	GO:0007099	centriole replication
0.46	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0009888	tissue development
0.40	GO:0043588	skin development
0.40	GO:0035107	appendage morphogenesis
0.39	GO:0009887	animal organ morphogenesis
0.39	GO:0009790	embryo development
0.38	GO:0001957	intramembranous ossification
0.38	GO:0051239	regulation of multicellular organismal process
0.38	GO:0032964	collagen biosynthetic process

0.47	GO:0004867	serine-type endopeptidase inhibitor activity
0.47	GO:0005201	extracellular matrix structural constituent
0.38	GO:0048407	platelet-derived growth factor binding
0.37	GO:0002020	protease binding
0.36	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding
0.35	GO:0016491	oxidoreductase activity
0.34	GO:0016209	antioxidant activity
0.34	GO:0005319	lipid transporter activity
0.34	GO:0020037	heme binding

0.46	GO:0005886	plasma membrane
0.45	GO:0005581	collagen trimer
0.44	GO:0044420	extracellular matrix component
0.43	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0005615	extracellular space
0.36	GO:0099512	supramolecular fiber
0.34	GO:0090665	glycoprotein complex
0.34	GO:0005737	cytoplasm
0.33	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.35

GO:0016491

sp|Q8SXY6|TMEDA_DROME
Transmembrane emp24 domain-containing protein bai
Search

0.64	Transmembrane emp24 domain-containing protein bai

0.47	GO:0048042	regulation of post-mating oviposition
0.47	GO:0061355	Wnt protein secretion
0.45	GO:0009953	dorsal/ventral pattern formation
0.39	GO:0035964	COPI-coated vesicle budding
0.39	GO:1902003	regulation of amyloid-beta formation
0.38	GO:0045055	regulated exocytosis
0.38	GO:0007030	Golgi organization
0.36	GO:0006886	intracellular protein transport
0.36	GO:0007309	oocyte axis specification
0.34	GO:0016567	protein ubiquitination

0.41	GO:0008565	protein transporter activity
0.38	GO:0019905	syntaxin binding
0.36	GO:0043130	ubiquitin binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0004842	ubiquitin-protein transferase activity

0.45	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.39	GO:0042589	zymogen granule membrane
0.39	GO:0070765	gamma-secretase complex
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0044431	Golgi apparatus part
0.30	GO:0016021	integral component of membrane

0.34

GO:0004842

tr|Q8SXY8|Q8SXY8_DROME
RE49901p
Search

0.26	Glucose-methanol-choline oxidoreductase

0.53	GO:0055114	oxidation-reduction process
0.39	GO:0045455	ecdysteroid metabolic process
0.38	GO:0006012	galactose metabolic process
0.36	GO:0006508	proteolysis

0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.40	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.39	GO:0003978	UDP-glucose 4-epimerase activity
0.33	GO:0043885	carbon-monoxide dehydrogenase (ferredoxin) activity

0.33	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:1.1

GO:0016614

tr|Q8SXZ5|Q8SXZ5_DROME
RE39957p
Search

0.55	GO:0019226	transmission of nerve impulse
0.54	GO:0042552	myelination
0.54	GO:0007422	peripheral nervous system development
0.53	GO:0050808	synapse organization
0.53	GO:0007411	axon guidance
0.46	GO:0002175	protein localization to paranode region of axon
0.45	GO:0045162	clustering of voltage-gated sodium channels
0.45	GO:0071205	protein localization to juxtaparanode region of axon
0.45	GO:0034113	heterotypic cell-cell adhesion
0.43	GO:0007043	cell-cell junction assembly

0.46	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.40	GO:0008061	chitin binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0046872	metal ion binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0016301	kinase activity
0.36	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0061783	peptidoglycan muralytic activity

0.45	GO:0033010	paranodal junction
0.45	GO:0043194	axon initial segment
0.45	GO:0033270	paranode region of axon
0.44	GO:0005576	extracellular region
0.44	GO:0036338	viral membrane
0.43	GO:0043209	myelin sheath
0.38	GO:0005618	cell wall
0.37	GO:0030425	dendrite
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.38

GO:0004553

tr|Q8SXZ6|Q8SXZ6_DROME
RE39769p
Search

0.11	gastrula zinc finger protein xFG20-1

0.42

GO:0006357

regulation of transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.42	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0046872	metal ion binding

0.39

GO:0005634

nucleus

tr|Q8SY02|Q8SY02_DROME
Solute carrier organic anion transporter family member
Search

0.62	Solute carrier organic anion transporter family member

0.57	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.41	GO:0070327	thyroid hormone transport
0.39	GO:0071702	organic substance transport
0.34	GO:0042403	thyroid hormone metabolic process
0.32	GO:0016310	phosphorylation

0.56	GO:0005215	transporter activity
0.32	GO:0016301	kinase activity

0.54	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8SY05|Q8SY05_DROME
RE26721p
Search

0.46	Lipoteichoic acid synthase 2

0.42	GO:0032504	multicellular organism reproduction
0.30	GO:0008152	metabolic process

0.33	GO:0005509	calcium ion binding
0.30	GO:0003824	catalytic activity

0.40	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

tr|Q8SY13|Q8SY13_DROME
Beat-IIIc, isoform A
Search

BEAT-IIIC

0.57	Muscle M-line assembly protein unc-89 (Fragment)

0.60	GO:0016201	synaptic target inhibition
0.56	GO:0008045	motor neuron axon guidance
0.45	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0051028	mRNA transport

0.32

GO:0003676

nucleic acid binding

0.35	GO:0005643	nuclear pore
0.30	GO:0016020	membrane

tr|Q8SY19|Q8SY19_DROME
Microsomal glutathione S-transferase-like, isoform A
Search

0.82	Glutathione transferase microsomal

0.35

GO:0006749

glutathione metabolic process

0.42

GO:0016740

transferase activity

0.37	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0016740

tr|Q8SY25|Q8SY25_DROME
RE05944p
Search

0.38	Sodium-coupled neutral amino acid transporter

0.39	GO:0003333	amino acid transmembrane transport
0.34	GO:0005980	glycogen catabolic process
0.34	GO:0005978	glycogen biosynthetic process
0.32	GO:0006413	translational initiation

0.39	GO:0015171	amino acid transmembrane transporter activity
0.35	GO:0004135	amylo-alpha-1,6-glucosidase activity
0.34	GO:0004134	4-alpha-glucanotransferase activity
0.32	GO:0003676	nucleic acid binding

0.30

GO:0016020

membrane

0.35

EC:3.2.1.33

GO:0004135

sp|Q8SY33|GAWKY_DROME
Protein Gawky
Search

0.85	GO:0035278	miRNA mediated inhibition of translation
0.61	GO:0045475	locomotor rhythm
0.60	GO:0001700	embryonic development via the syncytial blastoderm
0.54	GO:0032880	regulation of protein localization
0.54	GO:0006402	mRNA catabolic process

0.50	GO:0003676	nucleic acid binding
0.36	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.57	GO:0000932	P-body
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

tr|Q8SY34|Q8SY34_DROME
LD46604p
Search

0.57	Phosphatase 1 regulatory inhibitor subunit 16B

0.76	GO:0043666	regulation of phosphoprotein phosphatase activity
0.73	GO:0007476	imaginal disc-derived wing morphogenesis
0.42	GO:0006470	protein dephosphorylation
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0009058	biosynthetic process
0.32	GO:0006629	lipid metabolic process

0.82	GO:0017020	myosin phosphatase regulator activity
0.75	GO:0008157	protein phosphatase 1 binding
0.42	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0004622	lysophospholipase activity
0.37	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.35	GO:0070279	vitamin B6 binding
0.34	GO:0050662	coenzyme binding
0.33	GO:0043168	anion binding

0.41	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.42

GO:0004721

tr|Q8SY39|Q8SY39_DROME
LD28101p
Search

DDX54

0.54	DEAD box ATP-dependent RNA helicase

0.42	GO:0010501	RNA secondary structure unwinding
0.37	GO:1903507	negative regulation of nucleic acid-templated transcription
0.36	GO:0006396	RNA processing
0.32	GO:0035725	sodium ion transmembrane transport
0.31	GO:0006468	protein phosphorylation

0.76	GO:0004004	ATP-dependent RNA helicase activity
0.58	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0030331	estrogen receptor binding
0.39	GO:0003714	transcription corepressor activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0005272	sodium channel activity

0.60	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005794	Golgi apparatus
0.37	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q8SY41|BCAS3_DROME
Breast carcinoma-amplified sequence 3 homolog
Search

0.73	GO:0042594	response to starvation
0.71	GO:0044351	macropinocytosis
0.45	GO:0051895	negative regulation of focal adhesion assembly
0.45	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.45	GO:0071391	cellular response to estrogen stimulus
0.45	GO:0034260	negative regulation of GTPase activity
0.44	GO:0051491	positive regulation of filopodium assembly
0.44	GO:0010595	positive regulation of endothelial cell migration
0.44	GO:0090630	activation of GTPase activity
0.43	GO:0090316	positive regulation of intracellular protein transport

0.45	GO:0010698	acetyltransferase activator activity
0.45	GO:0035035	histone acetyltransferase binding
0.44	GO:0035257	nuclear hormone receptor binding
0.44	GO:0048487	beta-tubulin binding
0.43	GO:0042393	histone binding
0.42	GO:0003682	chromatin binding

0.56	GO:0005829	cytosol
0.44	GO:0035327	transcriptionally active chromatin
0.43	GO:0005881	cytoplasmic microtubule
0.43	GO:0031252	cell leading edge
0.42	GO:0045111	intermediate filament cytoskeleton
0.41	GO:0005730	nucleolus
0.36	GO:0071944	cell periphery
0.30	GO:0016020	membrane

tr|Q8SY49|Q8SY49_DROME
GH17676p
Search

0.37

GO:0003723

RNA binding

tr|Q8SY52|Q8SY52_DROME
Elastin-like, isoform A
Search

LOC108099655

0.86	collagen alpha-1(III) chain isoform X2

0.76	GO:0035094	response to nicotine
0.38	GO:0043149	stress fiber assembly
0.37	GO:0048513	animal organ development
0.37	GO:0014706	striated muscle tissue development
0.37	GO:0030198	extracellular matrix organization
0.37	GO:0061061	muscle structure development
0.37	GO:0030833	regulation of actin filament polymerization
0.36	GO:0050673	epithelial cell proliferation
0.36	GO:0007155	cell adhesion
0.36	GO:0006508	proteolysis

0.46	GO:0005201	extracellular matrix structural constituent
0.39	GO:0005544	calcium-dependent phospholipid binding
0.37	GO:0050840	extracellular matrix binding
0.37	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005509	calcium ion binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005581	collagen trimer
0.44	GO:0031012	extracellular matrix
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.37

GO:0004252

tr|Q8SY53|Q8SY53_DROME
GH11935p
Search

0.68	Oligosaccharyltransferase gamma subunit

0.50	GO:0018279	protein N-linked glycosylation via asparagine
0.48	GO:0035010	encapsulation of foreign target
0.46	GO:0050890	cognition
0.44	GO:1903830	magnesium ion transmembrane transport
0.44	GO:0016477	cell migration

0.45	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.45	GO:0015095	magnesium ion transmembrane transporter activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.49	GO:0008250	oligosaccharyltransferase complex
0.39	GO:0005739	mitochondrion
0.33	GO:0005887	integral component of plasma membrane

0.45

EC:2.4.1.119

GO:0004579

tr|Q8SY58|Q8SY58_DROME
CG4872
Search

0.37	Thiomorpholine-carboxylate dehydrogenase

0.61	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0055114	oxidation-reduction process

0.72	GO:0042562	hormone binding
0.65	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.63	GO:0003714	transcription corepressor activity
0.43	GO:0008473	ornithine cyclodeaminase activity

0.44	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.65	EC:1.4.1	GO:0016639
0.43	KEGG:R00671	GO:0008473

sp|Q8SY61|OB56D_DROME
General odorant-binding protein 56d
Search

0.97	General odorant-binding protein 56d

0.53	GO:0007606	sensory perception of chemical stimulus
0.40	GO:0042048	olfactory behavior
0.39	GO:0032504	multicellular organism reproduction
0.39	GO:0019236	response to pheromone

0.80

GO:0005549

odorant binding

0.41	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SY67|Q8SY67_DROME
CG6429
Search

0.37	Destabilase

0.41	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0032504	multicellular organism reproduction
0.34	GO:0009306	protein secretion
0.30	GO:0008152	metabolic process

0.79

GO:0003796

lysozyme activity

0.39	GO:0005615	extracellular space
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.2.1.17

GO:0003796

tr|Q8SY68|Q8SY68_DROME
RH62830p
Search

tr|Q8SY69|Q8SY69_DROME
MICOS complex subunit MIC10
Search

0.59	MICOS complex subunit MIC10

0.83

GO:0061617

MICOS complex

sp|Q8SY72|SMCO4_DROME
Single-pass membrane and coiled-coil domain-containing protein 4 homolog
Search

0.76	Single-pass membrane and coiled-coil domain-containing protein 4

0.30

GO:0008152

metabolic process

0.35

GO:0016829

lyase activity

0.30

GO:0044425

membrane part

0.35

EC:4

GO:0016829

tr|Q8SY76|Q8SY76_DROME
RH45738p
Search

sp|Q8SY96|NFU1_DROME
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
Search

0.89	Putative nifu-like domain-containing-containing protein (Fragment)

0.74	GO:0031163	metallo-sulfur cluster assembly
0.65	GO:0006790	sulfur compound metabolic process
0.63	GO:0051188	cofactor biosynthetic process
0.33	GO:0006470	protein dephosphorylation

0.64	GO:0051540	metal cluster binding
0.63	GO:0005506	iron ion binding
0.56	GO:0048037	cofactor binding
0.33	GO:0005515	protein binding
0.33	GO:0004721	phosphoprotein phosphatase activity
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005739	mitochondrion
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004721

tr|Q8SYA4|Q8SYA4_DROME
FI01448p
Search

0.97	immune-induced peptide 2

0.72	GO:0009617	response to bacterium
0.68	GO:0006952	defense response
0.64	GO:0019730	antimicrobial humoral response
0.42	GO:0008063	Toll signaling pathway

0.63	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|Q8SYC1|Q8SYC1_DROME
GEO08067p1
Search

0.30

GO:0044425

membrane part

tr|Q8SYC3|Q8SYC3_DROME
RE68569p
Search

0.70	Scavenger receptor class B member

0.34

GO:0006468

protein phosphorylation

0.34	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|Q8SYC4|Q8SYC4_DROME
RE68566p
Search

0.44	Putative phosphatidylinositol transfer protein sec14

0.30

GO:0044425

membrane part

tr|Q8SYC5|Q8SYC5_DROME
RE68347p
Search

0.21	Protein translocase subunit SecA

0.30

GO:0044425

membrane part

sp|Q8SYD0|TTC19_DROME
Tetratricopeptide repeat protein 19 homolog, mitochondrial
Search

0.77	Tetratricopeptide repeat protein 19, mitochondrial

0.86	GO:0007630	jump response
0.86	GO:0071632	optomotor response
0.81	GO:0034551	mitochondrial respiratory chain complex III assembly
0.35	GO:0055114	oxidation-reduction process

0.36

GO:0016491

oxidoreductase activity

0.59	GO:0005739	mitochondrion
0.41	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0016491

tr|Q8SYD9|Q8SYD9_DROME
Endophilin B, isoform A
Search

ENDOB

0.88	Endophilin B

0.51	GO:0061883	clathrin-dependent endocytosis involved in vitellogenesis
0.43	GO:0061024	membrane organization
0.40	GO:0010256	endomembrane system organization

0.41	GO:0042171	lysophosphatidic acid acyltransferase activity
0.39	GO:0005543	phospholipid binding

0.49	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SYF5|Q8SYF5_DROME
RE64043p
Search

0.48	GO:0048731	system development
0.47	GO:0035583	sequestering of TGFbeta in extracellular matrix
0.46	GO:0061430	bone trabecula morphogenesis
0.45	GO:0048468	cell development
0.45	GO:0008037	cell recognition
0.45	GO:0070167	regulation of biomineral tissue development
0.45	GO:0045669	positive regulation of osteoblast differentiation
0.44	GO:0030326	embryonic limb morphogenesis
0.42	GO:0048646	anatomical structure formation involved in morphogenesis
0.38	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.70	GO:0005509	calcium ion binding
0.54	GO:0005201	extracellular matrix structural constituent
0.35	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.35	GO:0030296	protein tyrosine kinase activator activity
0.34	GO:0001786	phosphatidylserine binding
0.34	GO:0030971	receptor tyrosine kinase binding
0.34	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0008061	chitin binding
0.34	GO:0060090	molecular adaptor activity
0.34	GO:0048018	receptor ligand activity

0.52	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0001527	microfibril
0.35	GO:0005737	cytoplasm
0.33	GO:0005615	extracellular space
0.33	GO:0031526	brush border membrane
0.33	GO:0009897	external side of plasma membrane
0.33	GO:0016324	apical plasma membrane
0.33	GO:0005905	clathrin-coated pit
0.33	GO:0030425	dendrite
0.33	GO:0030424	axon

0.33

EC:2.7.10.1

GO:0004714

tr|Q8SYF7|Q8SYF7_DROME
LP09246p
Search

0.39	Transmembrane protein 65

0.35	GO:0006030	chitin metabolic process
0.33	GO:0005975	carbohydrate metabolic process

0.36	GO:0005509	calcium ion binding
0.34	GO:0008061	chitin binding

0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q8SYG2|CSN3_DROME
COP9 signalosome complex subunit 3
Search

COPS3

0.73	COP9 signalosome complex subunit

0.51	GO:0048140	male germ-line cyst encapsulation
0.51	GO:0048142	germarium-derived cystoblast division
0.50	GO:0036099	female germ-line stem cell population maintenance
0.47	GO:0050821	protein stabilization
0.44	GO:0000338	protein deneddylation
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.37	GO:0001701	in utero embryonic development
0.33	GO:0065009	regulation of molecular function
0.32	GO:0016310	phosphorylation

0.33	GO:0005085	guanyl-nucleotide exchange factor activity
0.32	GO:0016301	kinase activity

0.81	GO:0008180	COP9 signalosome
0.39	GO:1905369	endopeptidase complex
0.38	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SYG3|Q8SYG3_DROME
RE63412p
Search

0.53	Ubiquitin-conjugating enzyme

0.44	GO:0000209	protein polyubiquitination
0.40	GO:0044257	cellular protein catabolic process
0.38	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0006508	proteolysis
0.35	GO:0071897	DNA biosynthetic process
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0006468	protein phosphorylation

0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.39	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0016874	ligase activity
0.35	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0003677	DNA binding

0.35	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39	EC:6	GO:0016874
0.42	KEGG:R03876	GO:0004842

tr|Q8SYH1|Q8SYH1_DROME
ACAT-related protein required for viability 1, isoform A
Search

0.38	ACAT-related protein required for viability 1, isoform A

0.73	GO:0051781	positive regulation of cell division
0.47	GO:0097036	regulation of plasma membrane sterol distribution
0.45	GO:0032366	intracellular sterol transport
0.43	GO:0006665	sphingolipid metabolic process
0.43	GO:0016125	sterol metabolic process

0.46	GO:0032541	cortical endoplasmic reticulum
0.41	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|Q8SYI7|Q8SYI7_DROME
RE57135p
Search

0.85	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
0.63	GO:0006974	cellular response to DNA damage stimulus
0.42	GO:0006414	translational elongation
0.40	GO:0055114	oxidation-reduction process
0.40	GO:0010883	regulation of lipid storage
0.37	GO:0006631	fatty acid metabolic process

0.48	GO:0051213	dioxygenase activity
0.42	GO:0003746	translation elongation factor activity
0.41	GO:0003924	GTPase activity
0.40	GO:0001883	purine nucleoside binding
0.40	GO:0019001	guanyl nucleotide binding
0.40	GO:0032549	ribonucleoside binding
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SYJ2|Q8SYJ2_DROME
GEO09626p1
Search

0.39	NADH ubiquinone dehydrogenase

0.38	GO:1902600	hydrogen ion transmembrane transport
0.37	GO:0022900	electron transport chain
0.36	GO:0046034	ATP metabolic process
0.35	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.34	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.34	GO:0045333	cellular respiration
0.34	GO:0016310	phosphorylation

0.37	GO:0015002	heme-copper terminal oxidase activity
0.37	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.37	GO:0015078	hydrogen ion transmembrane transporter activity
0.37	GO:0009055	electron transfer activity
0.36	GO:0003954	NADH dehydrogenase activity
0.34	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005751	mitochondrial respiratory chain complex IV
0.37	GO:0005747	mitochondrial respiratory chain complex I
0.36	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.30	GO:0016021	integral component of membrane

0.37

GO:0016676

tr|Q8SYJ9|Q8SYJ9_DROME
RE55868p
Search

YRDC

0.85	yrdC domain-containing protein, mitochondrial

0.44	GO:0051051	negative regulation of transport
0.43	GO:0002949	tRNA threonylcarbamoyladenosine modification
0.42	GO:0006379	mRNA cleavage
0.42	GO:0006450	regulation of translational fidelity
0.38	GO:0032774	RNA biosynthetic process
0.36	GO:0034645	cellular macromolecule biosynthetic process
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0009152	purine ribonucleotide biosynthetic process
0.34	GO:0046944	protein carbamoylation
0.33	GO:0034033	purine nucleoside bisphosphate biosynthetic process

0.77	GO:0003725	double-stranded RNA binding
0.45	GO:0016779	nucleotidyltransferase activity
0.41	GO:0000049	tRNA binding
0.39	GO:0140098	catalytic activity, acting on RNA
0.38	GO:0008270	zinc ion binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0034023	5-(carboxyamino)imidazole ribonucleotide mutase activity

0.37	GO:0005737	cytoplasm
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.45	EC:2.7.7	GO:0016779
0.34	KEGG:R00130	GO:0004140

tr|Q8SYK4|Q8SYK4_DROME
RE55691p
Search

sp|Q8SYK5|INSV_DROME
Protein insensitive
Search

0.12	Protein insensitive

0.78	GO:0045746	negative regulation of Notch signaling pathway
0.68	GO:0045892	negative regulation of transcription, DNA-templated
0.54	GO:0031937	positive regulation of chromatin silencing
0.53	GO:0001700	embryonic development via the syncytial blastoderm
0.47	GO:0045814	negative regulation of gene expression, epigenetic
0.46	GO:0016458	gene silencing
0.45	GO:0006325	chromatin organization
0.39	GO:0006351	transcription, DNA-templated
0.34	GO:0045666	positive regulation of neuron differentiation
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.87	GO:0043035	chromatin insulator sequence binding
0.74	GO:0003714	transcription corepressor activity
0.65	GO:0043565	sequence-specific DNA binding
0.40	GO:0005515	protein binding
0.35	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.34	GO:0001104	RNA polymerase II transcription cofactor activity

0.61	GO:0005634	nucleus
0.57	GO:0017053	transcriptional repressor complex
0.51	GO:0005704	polytene chromosome band
0.50	GO:0031974	membrane-enclosed lumen

tr|Q8SYL0|Q8SYL0_DROME
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
Search

0.40	Cdp-diacylglycerol--serine o-phosphatidyltransferase

0.79	GO:0032049	cardiolipin biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.33	GO:0005507	copper ion binding

0.36	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:2.7.8.5	GO:0008444
0.79	KEGG:R01801	GO:0008444

tr|Q8SYL1|Q8SYL1_DROME
Lethal (2) 09851, isoform A
Search

0.76	glutamate-rich WD repeat-containing protein 1

0.34	GO:0016573	histone acetylation
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.35	GO:0019904	protein domain specific binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0004402	histone acetyltransferase activity
0.34	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.34	GO:0005840	ribosome
0.30	GO:0044425	membrane part

0.34

GO:0004402

tr|Q8SYL7|Q8SYL7_DROME
UDP-glucuronosyltransferase
Search

0.52	UDP-glucuronosyltransferase

0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.30	GO:0008152	metabolic process

0.77	GO:0015020	glucuronosyltransferase activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003677	DNA binding

0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044425	membrane part

0.77

EC:2.4.1.17

GO:0015020

tr|Q8SYM0|Q8SYM0_DROME
Putative noncoding RNA 004:X
Search

tr|Q8SYM5|Q8SYM5_DROME
CG4324, isoform A
Search

SVOP

0.72	synaptic vesicle 2-related protein isoform X1

0.55	GO:0055085	transmembrane transport
0.34	GO:0008643	carbohydrate transport
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0022857	transmembrane transporter activity
0.32	GO:0016491	oxidoreductase activity

0.38	GO:0030672	synaptic vesicle membrane
0.37	GO:0030054	cell junction
0.30	GO:0044425	membrane part

0.32

GO:0016491

tr|Q8SYM9|Q8SYM9_DROME
CG5147
Search

RPC4

0.60	DNA-directed RNA polymerase III subunit RPC4

0.81

GO:0006383

transcription by RNA polymerase III

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding

0.81

GO:0005666

DNA-directed RNA polymerase III complex

0.70

EC:2.7.7.6

GO:0003899

tr|Q8SYN0|Q8SYN0_DROME
RE52086p
Search

0.77	Calmodulin-4

0.34	GO:0033036	macromolecule localization
0.33	GO:1990395	meiotic spindle pole body organization
0.33	GO:0009612	response to mechanical stimulus
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0065007	biological regulation
0.33	GO:0071702	organic substance transport
0.33	GO:0090307	mitotic spindle assembly
0.33	GO:0042886	amide transport
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0051641	cellular localization

0.70	GO:0005509	calcium ion binding
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0004012	phospholipid-translocating ATPase activity
0.33	GO:0003677	DNA binding
0.32	GO:0000287	magnesium ion binding
0.32	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005634	nucleus
0.33	GO:0035840	old growing cell tip
0.33	GO:0035841	new growing cell tip
0.33	GO:0035974	meiotic spindle pole body
0.33	GO:0000935	division septum
0.33	GO:0044732	mitotic spindle pole body
0.33	GO:0043332	mating projection tip
0.33	GO:0005802	trans-Golgi network
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0032440

tr|Q8SYP1|Q8SYP1_DROME
RE49668p
Search

0.38	Urokinase plasminogen activator surface receptor

0.35	GO:0016310	phosphorylation
0.34	GO:0055114	oxidation-reduction process

0.36	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.35	GO:0016301	kinase activity

0.30

GO:0031224

intrinsic component of membrane

0.36

EC:1.1

GO:0016614

tr|Q8SYP8|Q8SYP8_DROME
RE47911p
Search

0.11	Serendipity alpha

0.85	GO:0007349	cellularization
0.41	GO:0007015	actin filament organization
0.35	GO:0007155	cell adhesion

0.35

GO:0051015

actin filament binding

0.71	GO:0031941	filamentous actin
0.70	GO:0032154	cleavage furrow
0.49	GO:0005737	cytoplasm
0.37	GO:0005886	plasma membrane

tr|Q8SYP9|Q8SYP9_DROME
Mitochondrial ribosomal protein S5, isoform A
Search

0.93	Mitochondrial ribosomal protein S5, isoform A

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.33	GO:0006508	proteolysis
0.32	GO:0006259	DNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0008270	zinc ion binding
0.31	GO:0003677	DNA binding

0.61	GO:0005840	ribosome
0.39	GO:0005759	mitochondrial matrix
0.39	GO:0044445	cytosolic part
0.30	GO:0016020	membrane

tr|Q8SYQ4|Q8SYQ4_DROME
RE42475p
Search

0.44	DNA topoisomerase 2-alpha

0.41

GO:0016853

isomerase activity

0.49	GO:0005615	extracellular space
0.47	GO:0005829	cytosol
0.43	GO:0019867	outer membrane
0.30	GO:0044425	membrane part

0.41

GO:0016853

tr|Q8SYQ8|Q8SYQ8_DROME
CG3420, isoform A
Search

CISD3

0.71	CDGSH iron sulfur domain-containing protein 3

0.54	GO:0006537	glutamate biosynthetic process
0.42	GO:0055114	oxidation-reduction process
0.38	GO:0006508	proteolysis
0.33	GO:0007041	lysosomal transport

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.54	GO:0015930	glutamate synthase activity
0.40	GO:0008238	exopeptidase activity
0.37	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.33	GO:0051219	phosphoprotein binding
0.32	GO:0004872	receptor activity

0.56	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:1.4

GO:0015930

tr|Q8SYR5|Q8SYR5_DROME
GEO07715p1
Search

sp|Q8SYS7|NARF_DROME
Probable cytosolic Fe-S cluster assembly factor CG17683
Search

0.83	cytosolic Fe-S cluster assembly factor NARFL

0.71	GO:0016226	iron-sulfur cluster assembly
0.64	GO:0032364	oxygen homeostasis
0.58	GO:0002244	hematopoietic progenitor cell differentiation
0.58	GO:0001666	response to hypoxia
0.44	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0055114	oxidation-reduction process
0.38	GO:0002040	sprouting angiogenesis
0.37	GO:0006030	chitin metabolic process
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0032259	methylation

0.60	GO:0051536	iron-sulfur cluster binding
0.51	GO:0003954	NADH dehydrogenase activity
0.49	GO:0046872	metal ion binding
0.37	GO:0008061	chitin binding
0.36	GO:0008168	methyltransferase activity
0.36	GO:0004871	signal transducer activity
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.61	GO:0097361	CIA complex
0.38	GO:1905360	GTPase complex
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0098797	plasma membrane protein complex
0.35	GO:0005576	extracellular region

0.51

EC:1.6.99.3

GO:0003954

tr|Q8SYS8|Q8SYS8_DROME
RE37218p2
Search

0.40	Trypsin epsilon

0.61	GO:0006508	proteolysis
0.38	GO:0042060	wound healing
0.38	GO:0007599	hemostasis
0.38	GO:0050817	coagulation
0.34	GO:0044537	regulation of circulating fibrinogen levels
0.34	GO:1901552	positive regulation of endothelial cell development
0.34	GO:1903140	regulation of establishment of endothelial barrier
0.34	GO:0030195	negative regulation of blood coagulation
0.33	GO:0050728	negative regulation of inflammatory response
0.33	GO:0001889	liver development

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0008237	metallopeptidase activity
0.37	GO:0005509	calcium ion binding
0.33	GO:0005044	scavenger receptor activity

0.34	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0019897	extrinsic component of plasma membrane
0.32	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|Q8SYU5|Q8SYU5_DROME
RE33762p
Search

0.58	arrestin domain-containing protein 5

0.61

GO:0007165

signal transduction

0.30

GO:0044425

membrane part

sp|Q8SYV9|MTH14_DROME
Probable G-protein coupled receptor Mth-like 14
Search

MTH14

0.97	LOW QUALITY PROTEIN: probable G-protein coupled receptor Mth-like 14

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0006950	response to stress

0.71

GO:0004930

G-protein coupled receptor activity

0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q8SYY6|Q8SYY6_DROME
GEO09675p1
Search

SERP2

0.70	stress-associated endoplasmic reticulum protein 2

0.55	GO:0015031	protein transport
0.51	GO:0030968	endoplasmic reticulum unfolded protein response
0.47	GO:0060124	positive regulation of growth hormone secretion
0.45	GO:0046622	positive regulation of organ growth
0.45	GO:0032024	positive regulation of insulin secretion
0.45	GO:0006486	protein glycosylation
0.45	GO:0048644	muscle organ morphogenesis
0.45	GO:0010259	multicellular organism aging
0.44	GO:0001501	skeletal system development
0.43	GO:0009791	post-embryonic development

0.35	GO:0017056	structural constituent of nuclear pore
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.70	GO:0005783	endoplasmic reticulum
0.59	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.56	GO:0031984	organelle subcompartment
0.45	GO:0005881	cytoplasmic microtubule
0.34	GO:0015935	small ribosomal subunit
0.34	GO:0005643	nuclear pore
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SYY7|Q8SYY7_DROME
RE27547p
Search

0.16

alaserpin

0.44

GO:0004867

serine-type endopeptidase inhibitor activity

0.73

GO:0005615

extracellular space

tr|Q8SZ13|Q8SZ13_DROME
RE24163p
Search

0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0010468	regulation of gene expression

0.62	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

tr|Q8SZ15|Q8SZ15_DROME
RE23670p
Search

NOA1

0.73	nitric oxide-associated protein 1

0.38	GO:0042254	ribosome biogenesis
0.37	GO:0043457	regulation of cellular respiration
0.36	GO:0032543	mitochondrial translation
0.35	GO:0010941	regulation of cell death
0.32	GO:0006508	proteolysis

0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003924	GTPase activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0004252	serine-type endopeptidase activity

0.37	GO:0005739	mitochondrion
0.36	GO:0031312	extrinsic component of organelle membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0004252

sp|Q8SZ16|SDHF3_DROME
Succinate dehydrogenase assembly factor 3, mitochondrial
Search

0.87	Succinate dehydrogenase complex assembly factor 3

0.55	GO:0055093	response to hyperoxia
0.54	GO:0050881	musculoskeletal movement
0.52	GO:0006105	succinate metabolic process
0.48	GO:0006979	response to oxidative stress
0.45	GO:0097032	mitochondrial respiratory chain complex II biogenesis
0.45	GO:0034552	respiratory chain complex II assembly
0.44	GO:0006111	regulation of gluconeogenesis
0.43	GO:0033108	mitochondrial respiratory chain complex assembly
0.39	GO:0015976	carbon utilization
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.33	GO:0005506	iron ion binding
0.32	GO:0016787	hydrolase activity

0.60	GO:0005739	mitochondrion
0.43	GO:0031970	organelle envelope lumen

0.34

EC:1.13.11

GO:0016702

tr|Q8SZ23|Q8SZ23_DROME
CG8160
Search

0.74	glycine-rich protein DOT1

0.54	GO:0006260	DNA replication
0.36	GO:0006310	DNA recombination
0.36	GO:0006281	DNA repair
0.32	GO:0032774	RNA biosynthetic process

0.59	GO:0003697	single-stranded DNA binding
0.49	GO:0003723	RNA binding
0.36	GO:0004386	helicase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0042302	structural constituent of cuticle
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003896	DNA primase activity

0.39	GO:0019013	viral nucleocapsid
0.37	GO:0005576	extracellular region
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005581	collagen trimer
0.33	GO:1990077	primosome complex
0.33	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0003896

tr|Q8SZ30|Q8SZ30_DROME
RE19845p
Search

SPN-D

0.97	DNA repair protein RAD51 homolog 3 isoform X1

0.65	GO:0006281	DNA repair
0.56	GO:0009951	polarity specification of dorsal/ventral axis
0.56	GO:0030720	oocyte localization involved in germarium-derived egg chamber formation
0.55	GO:0009949	polarity specification of anterior/posterior axis
0.55	GO:0007294	germarium-derived oocyte fate determination
0.55	GO:0030717	karyosome formation
0.54	GO:0046843	dorsal appendage formation
0.53	GO:0008298	intracellular mRNA localization
0.51	GO:0031023	microtubule organizing center organization
0.51	GO:0007131	reciprocal meiotic recombination

0.69	GO:0008094	DNA-dependent ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0000150	recombinase activity
0.37	GO:0004520	endodeoxyribonuclease activity

0.40	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex
0.38	GO:0005657	replication fork
0.30	GO:0016020	membrane

tr|Q8SZ38|Q8SZ38_DROME
RE18076p
Search

tr|Q8SZ46|Q8SZ46_DROME
RE17220p
Search

0.18	Short-chain dehydrogenase

0.44

GO:0055114

oxidation-reduction process

0.45	GO:0016491	oxidoreductase activity
0.35	GO:0004312	fatty acid synthase activity
0.32	GO:0016787	hydrolase activity

0.30

GO:0044425

membrane part

0.45

GO:0016491

tr|Q8SZ49|Q8SZ49_DROME
GEO07444p1
Search

0.86	vitelline membrane protein Vm26Ab

0.41

GO:0007218

neuropeptide signaling pathway

0.43

GO:0042302

structural constituent of cuticle

0.30

GO:0044425

membrane part

tr|Q8SZ60|Q8SZ60_DROME
RE16127p
Search

0.54	CLIP-domain serine protease

0.61	GO:0006508	proteolysis
0.33	GO:0016569	covalent chromatin modification
0.32	GO:0007018	microtubule-based movement

0.69	GO:0004252	serine-type endopeptidase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003777	microtubule motor activity
0.31	GO:0016887	ATPase activity
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0000812	Swr1 complex
0.34	GO:0035267	NuA4 histone acetyltransferase complex
0.32	GO:0030286	dynein complex
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|Q8SZ63|GOGA5_DROME
Golgin-84
Search

0.89

Golgin-84

0.81	GO:0007030	Golgi organization
0.49	GO:0048193	Golgi vesicle transport
0.37	GO:0007018	microtubule-based movement
0.34	GO:0007165	signal transduction
0.34	GO:0006468	protein phosphorylation
0.33	GO:0006606	protein import into nucleus
0.33	GO:0007094	mitotic spindle assembly checkpoint
0.33	GO:0000226	microtubule cytoskeleton organization
0.32	GO:0007162	negative regulation of cell adhesion
0.32	GO:0006281	DNA repair

0.49	GO:0017137	Rab GTPase binding
0.48	GO:0042803	protein homodimerization activity
0.38	GO:0003774	motor activity
0.38	GO:0003779	actin binding
0.37	GO:0008017	microtubule binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0032403	protein complex binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0030674	protein binding, bridging

0.51	GO:0031985	Golgi cisterna
0.48	GO:0000139	Golgi membrane
0.48	GO:0005801	cis-Golgi network
0.39	GO:0016459	myosin complex
0.34	GO:0031410	cytoplasmic vesicle
0.33	GO:0012506	vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0005929	cilium
0.32	GO:0030870	Mre11 complex
0.32	GO:0030915	Smc5-Smc6 complex

0.32

EC:2.7.3

GO:0016775

tr|Q8SZ72|Q8SZ72_DROME
CG8646
Search

0.41	Arylsulfatase Jlike [Megachile rotundata]

0.33	GO:0098655	cation transmembrane transport
0.30	GO:0008152	metabolic process

0.75	GO:0008484	sulfuric ester hydrolase activity
0.33	GO:0008324	cation transmembrane transporter activity

0.34	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0044425	membrane part

0.75

EC:3.1.6

GO:0008484

tr|Q8SZ78|Q8SZ78_DROME
RE14222p
Search

0.55	adhesion G-protein coupled receptor G7

0.71	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0016525	negative regulation of angiogenesis

0.71	GO:0004930	G-protein coupled receptor activity
0.33	GO:0030246	carbohydrate binding

0.30

GO:0044425

membrane part

tr|Q8SZ87|Q8SZ87_DROME
Dim1
Search

TXNL4A

0.77	Mitosis protein dim1

0.75	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0051301	cell division
0.34	GO:0007049	cell cycle
0.34	GO:0009264	deoxyribonucleotide catabolic process

0.34	GO:0004139	deoxyribose-phosphate aldolase activity
0.33	GO:0005515	protein binding

0.76	GO:0005681	spliceosomal complex
0.48	GO:0031965	nuclear membrane
0.46	GO:0005682	U5 snRNP
0.45	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.44	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm

0.34	EC:4.1.2.4	GO:0004139
0.34	KEGG:R01066	GO:0004139

tr|Q8SZA1|Q8SZA1_DROME
GEO07330p1
Search

tr|Q8SZA8|Q8SZA8_DROME
Ferredoxin 2
Search

0.52	Adrenodoxin, mitochondrial

0.61	GO:0022900	electron transport chain
0.51	GO:0045966	positive regulation of ecdysteroid metabolic process
0.51	GO:0007554	regulation of ecdysteroid biosynthetic process
0.50	GO:0090031	positive regulation of steroid hormone biosynthetic process
0.50	GO:0035073	pupariation
0.45	GO:1904321	response to forskolin
0.44	GO:0071320	cellular response to cAMP
0.44	GO:1901655	cellular response to ketone
0.44	GO:0008203	cholesterol metabolic process
0.43	GO:0035690	cellular response to drug

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.34	GO:0008022	protein C-terminus binding
0.33	GO:0046872	metal ion binding
0.33	GO:0042803	protein homodimerization activity

0.39	GO:0005739	mitochondrion
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SZB7|Q8SZB7_DROME
RE07960p
Search

0.74	pyroglutamyl-peptidase 1

0.61	GO:0006508	proteolysis
0.34	GO:0006486	protein glycosylation
0.33	GO:0015937	coenzyme A biosynthetic process
0.32	GO:0016310	phosphorylation

0.83	GO:0016920	pyroglutamyl-peptidase activity
0.37	GO:0008234	cysteine-type peptidase activity
0.34	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.33	GO:0004140	dephospho-CoA kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0005829	cytosol
0.34	GO:0008250	oligosaccharyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.83	EC:3.4.19	GO:0016920
0.33	KEGG:R00130	GO:0004140

tr|Q8SZC2|Q8SZC2_DROME
GEO07280p1
Search

tr|Q8SZF4|Q8SZF4_DROME
RE02548p
Search

0.59	Leukocyte elastase inhibitor C

0.46	GO:0045861	negative regulation of proteolysis
0.44	GO:0052548	regulation of endopeptidase activity
0.44	GO:0051346	negative regulation of hydrolase activity
0.39	GO:0006508	proteolysis
0.35	GO:0045751	negative regulation of Toll signaling pathway
0.35	GO:0019732	antifungal humoral response
0.34	GO:0043362	nucleate erythrocyte maturation
0.33	GO:0030261	chromosome condensation
0.33	GO:0016569	covalent chromatin modification

0.45	GO:0004867	serine-type endopeptidase inhibitor activity
0.39	GO:0008233	peptidase activity
0.34	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.33	GO:0031490	chromatin DNA binding

0.73	GO:0005615	extracellular space
0.33	GO:0000790	nuclear chromatin
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.39

GO:0008233

tr|Q8SZI8|Q8SZI8_DROME
GEO05129p1
Search

0.76

GO:0010951

negative regulation of endopeptidase activity

0.79

GO:0004867

serine-type endopeptidase inhibitor activity

tr|Q8SZK5|Q8SZK5_DROME
RH26533p
Search

tr|Q8SZK9|Q8SZK9_DROME
C-type lectin 27kD, isoform A
Search

0.23	Peptidyl-prolyl cis-trans isomerase

0.69

GO:0030246

carbohydrate binding

0.30

GO:0044425

membrane part

tr|Q8SZM2|Q8SZM2_DROME
RH04334p
Search

0.61	Putative serine/threonine-protein kinase kinX

0.40	GO:0016310	phosphorylation
0.39	GO:0032392	DNA geometric change

0.46	GO:0004386	helicase activity
0.41	GO:0016301	kinase activity
0.40	GO:0003677	DNA binding
0.39	GO:0008094	DNA-dependent ATPase activity
0.37	GO:0140097	catalytic activity, acting on DNA
0.36	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|Q8SZN1|Q8SZN1_DROME
GEO08217p1
Search

0.76	GO:0010951	negative regulation of endopeptidase activity
0.45	GO:0006508	proteolysis

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.50	GO:0008234	cysteine-type peptidase activity

0.50

GO:0008234

tr|Q8SZN4|Q8SZN4_DROME
RH01588p
Search

0.76	LisH dimerization motif

0.71	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.54	GO:0051028	mRNA transport

0.41

GO:0003676

nucleic acid binding

0.61	GO:0005634	nucleus
0.49	GO:0012505	endomembrane system
0.46	GO:0031967	organelle envelope
0.46	GO:0005737	cytoplasm
0.45	GO:0043234	protein complex

tr|Q8SZP2|Q8SZP2_DROME
RE71854p
Search

0.46	Tweedle motif cuticular

0.67	GO:0040003	chitin-based cuticle development
0.53	GO:0010171	body morphogenesis
0.50	GO:0007018	microtubule-based movement
0.42	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0055085	transmembrane transport

0.69	GO:0005214	structural constituent of chitin-based cuticle
0.51	GO:0003777	microtubule motor activity
0.51	GO:0008017	microtubule binding
0.43	GO:0004930	G-protein coupled receptor activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0022857	transmembrane transporter activity
0.37	GO:0003676	nucleic acid binding

0.59	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0019013	viral nucleocapsid
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|Q8SZR6|Q8SZR6_DROME
LD44220p
Search

0.70	zinc finger HIT domain-containing protein 2

0.30

GO:0008152

metabolic process

0.54	GO:0046872	metal ion binding
0.30	GO:0003824	catalytic activity

tr|Q8SZT1|Q8SZT1_DROME
GH27708p
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0042023	DNA endoreduplication
0.53	GO:0007584	response to nutrient
0.53	GO:0007623	circadian rhythm
0.52	GO:0019216	regulation of lipid metabolic process
0.51	GO:0040007	growth
0.50	GO:0006366	transcription by RNA polymerase II
0.50	GO:0000278	mitotic cell cycle

0.61	GO:0003700	DNA binding transcription factor activity
0.45	GO:0043565	sequence-specific DNA binding
0.45	GO:0042803	protein homodimerization activity
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.33	GO:0016301	kinase activity

0.44	GO:0005634	nucleus
0.31	GO:0005840	ribosome

tr|Q8SZU0|Q8SZU0_DROME
CG9331, isoform C
Search

0.42	Glyoxylate reductase/hydroxypyruvate reductase a

0.53	GO:0055114	oxidation-reduction process
0.33	GO:1902679	negative regulation of RNA biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:0001510	RNA methylation

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.33	GO:0003714	transcription corepressor activity
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005829	cytosol
0.36	GO:0005576	extracellular region
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.66

EC:1.1.1

GO:0016616

tr|Q8SZU6|Q8SZU6_DROME
GH08896p
Search

0.56	CUE domain-containing protein 1

tr|Q8SZV0|Q8SZV0_DROME
GH07338p
Search

LOC108090270

0.69	sodium/potassium/calcium exchanger 6, mitochondrial

0.55	GO:0055085	transmembrane transport
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.35	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005509	calcium ion binding

0.30

GO:0016020

membrane

tr|Q8SZW5|Q8SZW5_DROME
Alpha-Esterase-3, isoform A
Search

0.31	Carboxylic ester hydrolase

0.32

GO:0009058

biosynthetic process

0.57	GO:0004104	cholinesterase activity
0.33	GO:0004386	helicase activity
0.33	GO:0016779	nucleotidyltransferase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.57

EC:3.1.1.8

GO:0004104

tr|Q8SZX1|Q8SZX1_DROME
CG7387
Search

0.61	DnaJ subfamily A member 3, mitochondrial

0.69	GO:0006457	protein folding
0.42	GO:0009408	response to heat
0.37	GO:0006260	DNA replication
0.32	GO:0000160	phosphorelay signal transduction system
0.32	GO:0045454	cell redox homeostasis

0.76	GO:0031072	heat shock protein binding
0.71	GO:0051082	unfolded protein binding
0.53	GO:0046872	metal ion binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003677	DNA binding

0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q8SZY4|Q8SZY4_DROME
Ecto-5'-nucleotidase 2, isoform A
Search

0.38	Nucleotidase

0.75	GO:0009166	nucleotide catabolic process
0.45	GO:0016311	dephosphorylation
0.38	GO:0046086	adenosine biosynthetic process
0.37	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.37	GO:0007159	leukocyte cell-cell adhesion
0.37	GO:0050728	negative regulation of inflammatory response
0.36	GO:0046688	response to copper ion
0.36	GO:0072523	purine-containing compound catabolic process
0.36	GO:0046033	AMP metabolic process
0.35	GO:0042737	drug catabolic process

0.59	GO:0016788	hydrolase activity, acting on ester bonds
0.53	GO:1901265	nucleoside phosphate binding
0.52	GO:0046872	metal ion binding
0.51	GO:0036094	small molecule binding
0.34	GO:0008768	UDP-sugar diphosphatase activity

0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.59

GO:0016788

tr|Q8SZY7|Q8SZY7_DROME
CG5026, isoform A
Search

MTMR9

0.71	Myotubularin

0.76	GO:0060304	regulation of phosphatidylinositol dephosphorylation
0.74	GO:0010922	positive regulation of phosphatase activity
0.67	GO:0050821	protein stabilization
0.64	GO:0010507	negative regulation of autophagy
0.59	GO:0046856	phosphatidylinositol dephosphorylation
0.45	GO:0006907	pinocytosis
0.42	GO:0030334	regulation of cell migration
0.41	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.41	GO:0006754	ATP biosynthetic process
0.41	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.72	GO:0019902	phosphatase binding
0.62	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.58	GO:0030234	enzyme regulator activity
0.55	GO:0004725	protein tyrosine phosphatase activity
0.41	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism

0.54	GO:0043234	protein complex
0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.62

EC:3.1.3.64

GO:0004438

tr|Q8SZY9|Q8SZY9_DROME
LD47413p
Search

LAS1L

0.56	Ribosomal biogenesis protein LAS1L

0.81	GO:0000478	endonucleolytic cleavage involved in rRNA processing
0.80	GO:0000470	maturation of LSU-rRNA
0.79	GO:0000460	maturation of 5.8S rRNA
0.70	GO:0006325	chromatin organization
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated

0.45

GO:0001104

RNA polymerase II transcription cofactor activity

0.78	GO:0030687	preribosome, large subunit precursor
0.45	GO:0016592	mediator complex

sp|Q8SZZ8|ICE2_DROME
Little elongation complex subunit 2
Search

0.87	Little elongation complex subunit 2

0.39	GO:0006351	transcription, DNA-templated
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression

0.79

GO:0008023

transcription elongation factor complex

tr|Q8T007|Q8T007_DROME
CG6791, isoform B
Search

0.12	zinc finger protein Xfin

0.39	GO:0097659	nucleic acid-templated transcription
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:0010467	gene expression
0.37	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.48	GO:0001134	transcription factor activity, transcription factor recruiting

0.40

GO:0005634

nucleus

tr|Q8T016|Q8T016_DROME
LD40049p
Search

0.42	cocaine esterase

0.41	GO:0097105	presynaptic membrane assembly
0.41	GO:0097104	postsynaptic membrane assembly
0.41	GO:0007158	neuron cell-cell adhesion
0.40	GO:0048488	synaptic vesicle endocytosis
0.39	GO:0050804	modulation of chemical synaptic transmission
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0006629	lipid metabolic process

0.53	GO:0004104	cholinesterase activity
0.40	GO:0042043	neurexin family protein binding
0.36	GO:0004872	receptor activity
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.32	GO:0016887	ATPase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0009986	cell surface
0.38	GO:0045202	synapse
0.37	GO:0005887	integral component of plasma membrane

0.53

EC:3.1.1.8

GO:0004104

tr|Q8T017|Q8T017_DROME
Double hit, isoform B
Search

0.80	regulator of G-protein signaling 17

0.72	GO:0043547	positive regulation of GTPase activity
0.40	GO:0009968	negative regulation of signal transduction

0.75	GO:0001965	G-protein alpha-subunit binding
0.73	GO:0005096	GTPase activator activity
0.71	GO:0005092	GDP-dissociation inhibitor activity

0.50	GO:0005802	trans-Golgi network
0.49	GO:0031410	cytoplasmic vesicle
0.45	GO:0005886	plasma membrane
0.38	GO:0043005	neuron projection
0.38	GO:0045202	synapse
0.38	GO:0030054	cell junction
0.38	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|Q8T043|Q8T043_DROME
CG3409, isoform A
Search

0.46	Monocarboxylate transporter

0.55	GO:0055085	transmembrane transport
0.39	GO:0015718	monocarboxylic acid transport

0.39

GO:0008028

monocarboxylic acid transmembrane transporter activity

0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|Q8T045|RUMI_DROME
O-glucosyltransferase rumi
Search

POGLUT1

0.82	O-glucosyltransferase rumi

0.59	GO:0045747	positive regulation of Notch signaling pathway
0.55	GO:0060537	muscle tissue development
0.54	GO:0043413	macromolecule glycosylation
0.53	GO:0009101	glycoprotein biosynthetic process
0.53	GO:2000035	regulation of stem cell division
0.52	GO:0042052	rhabdomere development
0.51	GO:0045746	negative regulation of Notch signaling pathway
0.50	GO:0007030	Golgi organization
0.50	GO:0007219	Notch signaling pathway
0.48	GO:0048318	axial mesoderm development

0.54	GO:0046527	glucosyltransferase activity
0.53	GO:0035252	UDP-xylosyltransferase activity
0.33	GO:0020037	heme binding
0.33	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding

0.58	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005576	extracellular region
0.34	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0046527

tr|Q8T051|Q8T051_DROME
LD28458p
Search

LOC108091664

0.86	zinc finger protein with KRAB and SCAN domains 8 isoform X1

0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.38	GO:0003700	DNA binding transcription factor activity
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0042802	identical protein binding
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.58

GO:0005634

nucleus

0.32

GO:0016705

sp|Q8T053|Y678_DROME
Uncharacterized zinc finger protein CG2678
Search

0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:0010468	regulation of gene expression
0.33	GO:0032259	methylation
0.33	GO:0007275	multicellular organism development

0.59	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008168	methyltransferase activity

0.57	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

0.33

GO:0008168

tr|Q8T062|Q8T062_DROME
LD25753p
Search

0.45	Endothelin-converting enzyme 1

0.61

GO:0006508

proteolysis

0.70	GO:0004222	metalloendopeptidase activity
0.33	GO:0046872	metal ion binding

0.49	GO:0016529	sarcoplasmic reticulum
0.45	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

sp|Q8T079|GLYR1_DROME
Putative oxidoreductase GLYR1 homolog
Search

0.38	NAD binding domain of 6-phosphogluconate dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.31	GO:0006098	pentose-phosphate shunt

0.75	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.67	GO:0051287	NAD binding
0.33	GO:0008679	2-hydroxy-3-oxopropionate reductase activity
0.31	GO:0008137	NADH dehydrogenase (ubiquinone) activity

0.37	GO:0005705	polytene chromosome interband
0.31	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:1.1.1.44

GO:0004616

sp|Q8T088|WDR55_DROME
WD repeat-containing protein 55 homolog
Search

0.57	WD repeat-containing protein 55

0.76	GO:0050829	defense response to Gram-negative bacterium
0.46	GO:0042273	ribosomal large subunit biogenesis
0.44	GO:0006364	rRNA processing
0.39	GO:0005975	carbohydrate metabolic process
0.38	GO:0031642	negative regulation of myelination
0.37	GO:0045746	negative regulation of Notch signaling pathway
0.37	GO:0001525	angiogenesis
0.37	GO:0032006	regulation of TOR signaling
0.34	GO:0035725	sodium ion transmembrane transport
0.34	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay

0.41	GO:0016757	transferase activity, transferring glycosyl groups
0.35	GO:0005272	sodium channel activity
0.34	GO:0016905	myosin heavy chain kinase activity
0.33	GO:0003964	RNA-directed DNA polymerase activity

0.30

GO:0016020

membrane

0.41

GO:0016757

tr|Q8T092|Q8T092_DROME
CG4282
Search

0.51	transcription factor grauzone

0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.34	GO:0031167	rRNA methylation

0.60	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0003700	DNA binding transcription factor activity
0.35	GO:0016433	rRNA (adenine) methyltransferase activity

0.58

GO:0005634

nucleus

0.35

GO:0016433

sp|Q8T0B1|NEPR1_DROME
Nuclear envelope phosphatase-regulatory subunit 1 homolog
Search

0.80	Nuclear envelope phosphatase-regulatory subunit

0.85	GO:0035307	positive regulation of protein dephosphorylation
0.51	GO:0010867	positive regulation of triglyceride biosynthetic process
0.46	GO:0034504	protein localization to nucleus
0.37	GO:0006629	lipid metabolic process
0.35	GO:0007077	mitotic nuclear envelope disassembly

0.33

GO:0005515

protein binding

0.86	GO:0071595	Nem1-Spo7 phosphatase complex
0.47	GO:0031965	nuclear membrane
0.42	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q8T0D1|Q8T0D1_DROME
LD10183p
Search

0.37

GO:0010951

negative regulation of endopeptidase activity

0.74	GO:0008157	protein phosphatase 1 binding
0.63	GO:0008270	zinc ion binding
0.41	GO:0003676	nucleic acid binding
0.37	GO:0004867	serine-type endopeptidase inhibitor activity

0.61	GO:0005634	nucleus
0.37	GO:0005578	proteinaceous extracellular matrix

tr|Q8T0D3|Q8T0D3_DROME
Dek, isoform B
Search

DEK

0.93	Putative chromatin-associated protein dek

0.53	GO:2000779	regulation of double-strand break repair
0.50	GO:0006338	chromatin remodeling
0.39	GO:0042254	ribosome biogenesis
0.39	GO:0016072	rRNA metabolic process
0.38	GO:0006396	RNA processing
0.37	GO:0035023	regulation of Rho protein signal transduction
0.37	GO:0065009	regulation of molecular function
0.36	GO:0032784	regulation of DNA-templated transcription, elongation
0.36	GO:0043412	macromolecule modification
0.35	GO:0044267	cellular protein metabolic process

0.51	GO:0042393	histone binding
0.50	GO:0003682	chromatin binding
0.41	GO:0003677	DNA binding
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0003723	RNA binding
0.35	GO:0090736	MATH domain binding
0.35	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0008047	enzyme activator activity
0.35	GO:0016301	kinase activity

0.61	GO:0005654	nucleoplasm
0.42	GO:0034457	Mpp10 complex
0.41	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0032040	small-subunit processome
0.35	GO:0031430	M band
0.34	GO:0044427	chromosomal part
0.34	GO:0043614	multi-eIF complex
0.34	GO:0030687	preribosome, large subunit precursor
0.34	GO:0033202	DNA helicase complex
0.34	GO:0022627	cytosolic small ribosomal subunit

0.35

GO:0016773

sp|Q8T0D4|TANT_DROME
Protein tantalus
Search

0.79

GO:0007423

sensory organ development

0.43	GO:0005515	protein binding
0.40	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.44	GO:0005694	chromosome

tr|Q8T0D9|Q8T0D9_DROME
LD08718p
Search

0.41	GO:0061158	3'-UTR-mediated mRNA destabilization
0.41	GO:2000625	regulation of miRNA catabolic process
0.41	GO:1904636	response to ionomycin
0.40	GO:1903936	cellular response to sodium arsenite
0.40	GO:0071362	cellular response to ether
0.40	GO:1902714	negative regulation of interferon-gamma secretion
0.40	GO:0044828	negative regulation by host of viral genome replication
0.40	GO:0055118	negative regulation of cardiac muscle contraction
0.40	GO:0050713	negative regulation of interleukin-1 beta secretion
0.40	GO:1904468	negative regulation of tumor necrosis factor secretion

0.53	GO:0046872	metal ion binding
0.40	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.40	GO:0035613	RNA stem-loop binding
0.40	GO:0035198	miRNA binding
0.39	GO:0009378	four-way junction helicase activity
0.38	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.38	GO:0003682	chromatin binding
0.38	GO:0004532	exoribonuclease activity
0.37	GO:0043022	ribosome binding
0.37	GO:0004521	endoribonuclease activity

0.45	GO:0000932	P-body
0.42	GO:0005654	nucleoplasm
0.40	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.39	GO:0009379	Holliday junction helicase complex
0.39	GO:0005791	rough endoplasmic reticulum
0.37	GO:0005856	cytoskeleton
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

tr|Q8T0G1|Q8T0G1_DROME
LD05335p
Search

0.46	UDP glucose:glycoprotein glucosyltransferase

0.61	GO:0098655	cation transmembrane transport
0.57	GO:0010043	response to zinc ion
0.53	GO:0097501	stress response to metal ion
0.52	GO:0061088	regulation of sequestering of zinc ion
0.46	GO:0009636	response to toxic substance
0.45	GO:0006829	zinc II ion transport
0.44	GO:0051050	positive regulation of transport
0.39	GO:0098660	inorganic ion transmembrane transport
0.36	GO:0043044	ATP-dependent chromatin remodeling
0.35	GO:0046686	response to cadmium ion

0.61	GO:0008324	cation transmembrane transporter activity
0.39	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.36	GO:0031491	nucleosome binding
0.34	GO:0004386	helicase activity
0.34	GO:0016887	ATPase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0030672	synaptic vesicle membrane
0.45	GO:0005770	late endosome
0.44	GO:0043005	neuron projection
0.37	GO:0005765	lysosomal membrane
0.36	GO:0016589	NURF complex
0.36	GO:0010008	endosome membrane
0.36	GO:0030054	cell junction
0.35	GO:0044841	gut granule membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

tr|Q8T0G4|Q8T0G4_DROME
Conundrum, isoform A
Search

0.65	Rho GTPase-activating protein conundrum

0.60	GO:0007165	signal transduction
0.54	GO:0034260	negative regulation of GTPase activity
0.50	GO:0008284	positive regulation of cell proliferation
0.49	GO:0043547	positive regulation of GTPase activity
0.40	GO:0007018	microtubule-based movement
0.35	GO:0030042	actin filament depolymerization
0.34	GO:1902531	regulation of intracellular signal transduction
0.34	GO:2000145	regulation of cell motility
0.33	GO:0030833	regulation of actin filament polymerization
0.33	GO:0001934	positive regulation of protein phosphorylation

0.49	GO:0005096	GTPase activator activity
0.40	GO:0003779	actin binding
0.40	GO:0003777	microtubule motor activity
0.40	GO:0008017	microtubule binding
0.36	GO:0005524	ATP binding
0.35	GO:0046872	metal ion binding
0.33	GO:0045296	cadherin binding
0.32	GO:0016301	kinase activity

0.54	GO:0045179	apical cortex
0.40	GO:0015629	actin cytoskeleton
0.39	GO:0044430	cytoskeletal part
0.38	GO:0030054	cell junction
0.37	GO:0043234	protein complex
0.35	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.33	GO:0016607	nuclear speck
0.30	GO:0016021	integral component of membrane

tr|Q8T0J9|Q8T0J9_DROME
GEO09379p1
Search

tr|Q8T0L3|Q8T0L3_DROME
GH24511p
Search

0.69	Ubiquitin modifier-activating enzyme

0.60	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process
0.50	GO:0035096	larval midgut cell programmed cell death
0.49	GO:0016322	neuron remodeling
0.49	GO:0016319	mushroom body development
0.48	GO:0030707	ovarian follicle cell development
0.47	GO:0019915	lipid storage
0.46	GO:0008283	cell proliferation
0.46	GO:0040008	regulation of growth
0.45	GO:0006914	autophagy

0.76	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003777	microtubule motor activity
0.38	GO:0008017	microtubule binding
0.34	GO:0016881	acid-amino acid ligase activity
0.34	GO:0003910	DNA ligase (ATP) activity
0.34	GO:0016740	transferase activity
0.33	GO:0003676	nucleic acid binding

0.46	GO:0030425	dendrite
0.43	GO:0030057	desmosome
0.42	GO:0030867	rough endoplasmic reticulum membrane
0.42	GO:0000792	heterochromatin
0.42	GO:0005765	lysosomal membrane
0.41	GO:0010008	endosome membrane
0.39	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion
0.35	GO:0070062	extracellular exosome

0.34

EC:6.3.2

GO:0016881

tr|Q8T0M4|Q8T0M4_DROME
GH22493p
Search

0.85	Twin of eyg, isoform B

0.68	GO:0007275	multicellular organism development
0.61	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0006351	transcription, DNA-templated
0.48	GO:0060429	epithelium development
0.46	GO:0009653	anatomical structure morphogenesis
0.35	GO:0016310	phosphorylation

0.57	GO:0043565	sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q8T0N5|Q8T0N5_DROME
CG8768
Search

0.38	Nucleoside diphosphate sugar epimerase

0.37	GO:0051301	cell division
0.33	GO:0055114	oxidation-reduction process

0.60	GO:0050662	coenzyme binding
0.33	GO:0016491	oxidoreductase activity

0.30

GO:0044425

membrane part

0.33

GO:0016491

tr|Q8T0P4|Q8T0P4_DROME
GH15428p
Search

0.70	GO:0030163	protein catabolic process
0.67	GO:0051301	cell division
0.60	GO:0006508	proteolysis

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.60	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|Q8T0Q4|Q8T0Q4_DROME
GH13992p
Search

0.73	Charged multivesicular body protein 4b

0.79	GO:0007034	vacuolar transport
0.49	GO:0048132	female germ-line stem cell asymmetric division
0.48	GO:0044130	negative regulation of growth of symbiont in host
0.48	GO:0016322	neuron remodeling
0.48	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.47	GO:0045746	negative regulation of Notch signaling pathway
0.47	GO:0048813	dendrite morphogenesis
0.47	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.46	GO:0032509	endosome transport via multivesicular body sorting pathway
0.46	GO:0000281	mitotic cytokinesis

0.33	GO:0005515	protein binding
0.33	GO:0005215	transporter activity
0.33	GO:0003700	DNA binding transcription factor activity

0.50	GO:1990635	proximal dendrite
0.48	GO:0045169	fusome
0.47	GO:0005771	multivesicular body
0.47	GO:0070938	contractile ring
0.46	GO:0030496	midbody
0.46	GO:0043025	neuronal cell body
0.36	GO:0000815	ESCRT III complex
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|Q8T0Q8|Q8T0Q8_DROME
Delta-1-Pyrroline-5-carboxylate dehydrogenase 2, isoform A
Search

0.31	Pyrroline-5-carboxylate dehydrogenase

0.75	GO:0010133	proline catabolic process to glutamate
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0007005	mitochondrion organization
0.37	GO:0006368	transcription elongation from RNA polymerase II promoter
0.36	GO:0016570	histone modification
0.35	GO:0019470	4-hydroxyproline catabolic process
0.33	GO:0046487	glyoxylate metabolic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0006091	generation of precursor metabolites and energy

0.76	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity
0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.43	GO:0042802	identical protein binding
0.33	GO:0005198	structural molecule activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0009055	electron transfer activity

0.42	GO:0005739	mitochondrion
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.37	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0005634	nucleus
0.35	GO:0045111	intermediate filament cytoskeleton
0.34	GO:0043234	protein complex
0.34	GO:0099512	supramolecular fiber
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:1.5.1.12

GO:0003842

tr|Q8T0R3|Q8T0R3_DROME
GH12815p
Search

0.68	GO:0006099	tricarboxylic acid cycle
0.35	GO:0006102	isocitrate metabolic process
0.32	GO:0032259	methylation

0.81	GO:0004449	isocitrate dehydrogenase (NAD+) activity
0.68	GO:0051287	NAD binding
0.64	GO:0000287	magnesium ion binding
0.32	GO:0008168	methyltransferase activity

0.58	GO:0005739	mitochondrion
0.39	GO:0043209	myelin sheath
0.36	GO:0045242	isocitrate dehydrogenase complex (NAD+)
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:1.1.1.41

GO:0004449

sp|Q8T0R7|IDGF5_DROME
Chitinase-like protein Idgf5
Search

0.35	Glycosyl hydrolase

0.61	GO:0040003	chitin-based cuticle development
0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0007444	imaginal disc development
0.57	GO:0042060	wound healing
0.55	GO:0018990	ecdysis, chitin-based cuticle
0.40	GO:0006032	chitin catabolic process
0.39	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043066	negative regulation of apoptotic process
0.35	GO:0006034	cuticle chitin metabolic process

0.77	GO:0008061	chitin binding
0.63	GO:0008084	imaginal disc growth factor receptor binding
0.55	GO:0004568	chitinase activity
0.33	GO:0030246	carbohydrate binding

0.43	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.55

GO:0004568

tr|Q8T0S3|Q8T0S3_DROME
CG7149, isoform A
Search

EPT1

0.43	CDP-alcohol phosphatidyltransferase

0.68	GO:0008654	phospholipid biosynthetic process
0.35	GO:1903955	positive regulation of protein targeting to mitochondrion
0.35	GO:0046337	phosphatidylethanolamine metabolic process
0.34	GO:0045017	glycerolipid biosynthetic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.72	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.34	GO:0008080	N-acetyltransferase activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003723	RNA binding

0.33	GO:0071203	WASH complex
0.30	GO:0016020	membrane

0.72

EC:2.7.8

GO:0016780

sp|Q8T0S6|HIPPO_DROME
Serine/threonine-protein kinase hippo
Search

0.40	Serine/threonine-protein kinase hippo

0.65	GO:0045464	R8 cell fate specification
0.64	GO:0046666	retinal cell programmed cell death
0.63	GO:0060253	negative regulation of glial cell proliferation
0.63	GO:0006468	protein phosphorylation
0.63	GO:0097202	activation of cysteine-type endopeptidase activity
0.63	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.62	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.61	GO:0007298	border follicle cell migration
0.60	GO:0002011	morphogenesis of an epithelial sheet
0.60	GO:0072089	stem cell proliferation

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0042803	protein homodimerization activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005057	signal transducer activity, downstream of receptor

0.41	GO:0005737	cytoplasm
0.39	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.67

GO:0004674

tr|Q8T0T9|Q8T0T9_DROME
GH07209p
Search

0.41	Ubiquitinyl hydrolase 1

0.33	GO:0006508	proteolysis
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
0.34	GO:0008236	serine-type peptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.34

EC:1.6.2.2

GO:0004128

tr|Q8T0U2|Q8T0U2_DROME
CG5089
Search

tr|Q8T0V8|Q8T0V8_DROME
GH01042p
Search

0.59	transforming growth factor beta-1-induced transcript 1 protein isoform X1

0.72	GO:0007160	cell-matrix adhesion
0.48	GO:0046843	dorsal appendage formation
0.48	GO:1901739	regulation of myoblast fusion
0.47	GO:0035218	leg disc development
0.46	GO:0035220	wing disc development
0.44	GO:0043087	regulation of GTPase activity
0.43	GO:0010506	regulation of autophagy
0.40	GO:0007016	cytoskeletal anchoring at plasma membrane
0.36	GO:0050859	negative regulation of B cell receptor signaling pathway
0.35	GO:0033628	regulation of cell adhesion mediated by integrin

0.54	GO:0046872	metal ion binding
0.34	GO:0003712	transcription cofactor activity

0.61	GO:0005856	cytoskeleton
0.48	GO:0005927	muscle tendon junction
0.46	GO:0005925	focal adhesion
0.38	GO:0005829	cytosol
0.35	GO:0016607	nuclear speck
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane

tr|Q8T0X8|Q8T0X8_DROME
Chemosensory protein A 29a
Search

0.92	Chemosensory protein A 29a

0.85	GO:0043695	detection of pheromone
0.73	GO:0007606	sensory perception of chemical stimulus
0.43	GO:0032367	intracellular cholesterol transport

0.51	GO:0005576	extracellular region
0.34	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q8T390|SH3G3_DROME
Endophilin-A
Search

0.32	Fatty alcohol acetyltransferase

0.71	GO:0006897	endocytosis
0.53	GO:0097753	membrane bending
0.53	GO:0097749	membrane tubulation
0.50	GO:0097320	plasma membrane tubulation
0.50	GO:0036465	synaptic vesicle recycling
0.49	GO:0000045	autophagosome assembly
0.49	GO:0050803	regulation of synapse structure or activity
0.48	GO:0099003	vesicle-mediated transport in synapse
0.47	GO:0009267	cellular response to starvation

0.48	GO:0042171	lysophosphatidic acid acyltransferase activity
0.46	GO:0005543	phospholipid binding
0.33	GO:0005515	protein binding

0.51	GO:0061174	type I terminal bouton
0.49	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q8T3J1|Q8T3J1_DROME
SD02419p
Search

sp|Q8T3L6|FABD_DROME
Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial
Search

0.40	Malonyl CoA-acyl carrier protein transacylase

0.43	GO:0042967	acyl-carrier-protein biosynthetic process
0.40	GO:0006633	fatty acid biosynthetic process
0.36	GO:0032447	protein urmylation
0.36	GO:0034227	tRNA thio-modification
0.36	GO:0002098	tRNA wobble uridine modification
0.34	GO:0000387	spliceosomal snRNP assembly
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:0055114	oxidation-reduction process

0.50	GO:0016740	transferase activity
0.35	GO:0000049	tRNA binding
0.34	GO:0031177	phosphopantetheine binding
0.32	GO:0016788	hydrolase activity, acting on ester bonds
0.32	GO:0016491	oxidoreductase activity

0.38	GO:0005739	mitochondrion
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.50

GO:0016740

tr|Q8T3P2|Q8T3P2_DROME
GM01014p
Search

tr|Q8T3P5|Q8T3P5_DROME
AT26438p
Search

0.30

GO:0044425

membrane part

tr|Q8T3Q4|Q8T3Q4_DROME
AT11120p
Search

0.64	outer dense fiber protein 3-B

0.44	GO:0051260	protein homooligomerization
0.43	GO:0006289	nucleotide-excision repair
0.42	GO:0008654	phospholipid biosynthetic process

0.45	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity
0.43	GO:0003684	damaged DNA binding
0.37	GO:0046872	metal ion binding

0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:2.3.1.51

GO:0003841

tr|Q8T3R9|Q8T3R9_DROME
AT03531p
Search

0.86	cilia- and flagella-associated protein 161

0.49

GO:0006508

proteolysis

0.53

GO:0004252

serine-type endopeptidase activity

0.56

GO:0031514

motile cilium

0.53

GO:0004252

sp|Q8T3U2|RS23_DROME
40S ribosomal protein S23
Search

0.53	Small subunit ribosomal protein S23e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64

GO:0003735

structural constituent of ribosome

0.70	GO:0015935	small ribosomal subunit
0.46	GO:0022626	cytosolic ribosome
0.38	GO:0042788	polysomal ribosome
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

tr|Q8T3V6|Q8T3V6_DROME
AT29239p
Search

0.89	Mitochondrial/chloroplast ribosomal protein L4/L29

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.33	GO:0098869	cellular oxidant detoxification
0.33	GO:0045454	cell redox homeostasis
0.33	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.33	GO:0006754	ATP biosynthetic process
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0051920	peroxiredoxin activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.79	GO:0005761	mitochondrial ribosome
0.46	GO:0000315	organellar large ribosomal subunit
0.34	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.11.1.15

GO:0051920

tr|Q8T3V7|Q8T3V7_DROME
AT29119p
Search

0.79	Radial spoke head protein 9

0.86	GO:0060294	cilium movement involved in cell motility
0.85	GO:0044458	motile cilium assembly
0.84	GO:0035082	axoneme assembly

tr|Q8T3W3|Q8T3W3_DROME
AT27838p
Search

0.30

GO:0044425

membrane part

tr|Q8T3W6|Q8T3W6_DROME
AT27166p
Search

0.38

GO:0032259

methylation

0.62	GO:0005515	protein binding
0.38	GO:0008168	methyltransferase activity

0.38

GO:0008168

tr|Q8T3W8|Q8T3W8_DROME
AT27079p
Search

0.78	SCP-containing protein A

0.61

GO:0032504

multicellular organism reproduction

0.66

GO:0005576

extracellular region

sp|Q8T3X9|ISCA1_DROME
Iron-sulfur cluster assembly 1 homolog, mitochondrial
Search

ISCA1

0.89	Iron-sulfur cluster assembly

0.78	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.42	GO:0016226	iron-sulfur cluster assembly
0.39	GO:0006783	heme biosynthetic process
0.36	GO:0071000	response to magnetism
0.34	GO:0050886	endocrine process
0.33	GO:0016579	protein deubiquitination
0.32	GO:0044281	small molecule metabolic process

0.64	GO:0051536	iron-sulfur cluster binding
0.62	GO:0005198	structural molecule activity
0.43	GO:0008198	ferrous iron binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0016779	nucleotidyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.42

GO:0005759

mitochondrial matrix

0.34

EC:3.4.19.12

GO:0036459

sp|Q8T3Y0|SINAL_DROME
Probable E3 ubiquitin-protein ligase sinah
Search

0.53	E3 ubiquitin-protein ligase sina

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination
0.70	GO:0007275	multicellular organism development
0.51	GO:0010498	proteasomal protein catabolic process
0.46	GO:2000027	regulation of organ morphogenesis
0.45	GO:0051960	regulation of nervous system development
0.45	GO:0060284	regulation of cell development
0.43	GO:0030154	cell differentiation
0.37	GO:0007601	visual perception
0.34	GO:0050896	response to stimulus

0.63	GO:0008270	zinc ion binding
0.45	GO:0043621	protein self-association
0.42	GO:0042802	identical protein binding
0.40	GO:0016874	ligase activity
0.36	GO:0004842	ubiquitin-protein transferase activity

0.61	GO:0005634	nucleus
0.43	GO:0000151	ubiquitin ligase complex
0.36	GO:0005737	cytoplasm

0.40	EC:6	GO:0016874
0.36	KEGG:R03876	GO:0004842

tr|Q8T3Y1|Q8T3Y1_DROME
AT26187p
Search

0.43	GO:0051568	histone H3-K4 methylation
0.37	GO:1903474	anchoring of the mitotic actomyosin contractile ring to the plasma membrane
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0016070	RNA metabolic process
0.34	GO:0033363	secretory granule organization
0.34	GO:0010467	gene expression
0.33	GO:0007162	negative regulation of cell adhesion
0.33	GO:0007030	Golgi organization

0.82	GO:0045322	unmethylated CpG binding
0.57	GO:0008270	zinc ion binding
0.34	GO:0042302	structural constituent of cuticle
0.33	GO:1990380	Lys48-specific deubiquitinase activity
0.33	GO:0008452	RNA ligase activity
0.33	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0030145	manganese ion binding
0.33	GO:0003723	RNA binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0017111	nucleoside-triphosphatase activity

0.75	GO:0048188	Set1C/COMPASS complex
0.34	GO:0035145	exon-exon junction complex
0.34	GO:0070971	endoplasmic reticulum exit site
0.33	GO:0000137	Golgi cis cisterna
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:6.5.1

GO:0008452

tr|Q8T3Z0|Q8T3Z0_DROME
AT25102p
Search

TEKT1

0.73

Tektin C

0.60	GO:0070588	calcium ion transmembrane transport
0.54	GO:0006468	protein phosphorylation
0.51	GO:0060294	cilium movement involved in cell motility
0.50	GO:0030317	flagellated sperm motility
0.47	GO:0060271	cilium assembly

0.61	GO:0005262	calcium channel activity
0.58	GO:0004674	protein serine/threonine kinase activity
0.48	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0005515	protein binding

0.49	GO:0036126	sperm flagellum
0.41	GO:0005634	nucleus
0.38	GO:0005840	ribosome
0.30	GO:0005875	microtubule associated complex
0.30	GO:0031224	intrinsic component of membrane

0.58

GO:0004674

tr|Q8T3Z4|Q8T3Z4_DROME
AT24727p
Search

0.10	MYND finger protein

0.49	GO:0010629	negative regulation of gene expression
0.45	GO:0001522	pseudouridine synthesis
0.42	GO:0006396	RNA processing
0.38	GO:0006898	receptor-mediated endocytosis
0.35	GO:0006334	nucleosome assembly
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0007165	signal transduction

0.58	GO:0042826	histone deacetylase binding
0.47	GO:0046872	metal ion binding
0.45	GO:0009982	pseudouridine synthase activity
0.41	GO:0003723	RNA binding
0.40	GO:0005044	scavenger receptor activity
0.39	GO:0031418	L-ascorbic acid binding
0.37	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0003677	DNA binding

0.35	GO:0000786	nucleosome
0.30	GO:0016020	membrane

0.45

EC:5.4.99.12

GO:0009982

tr|Q8T403|Q8T403_DROME
AT23551p
Search

0.11	male-specific sperm protein Mst84Dd

0.66	GO:0007283	spermatogenesis
0.59	GO:0007281	germ cell development
0.59	GO:0030317	flagellated sperm motility
0.59	GO:0035082	axoneme assembly
0.50	GO:0007275	multicellular organism development
0.43	GO:0001558	regulation of cell growth

0.44	GO:0005520	insulin-like growth factor binding
0.42	GO:0019904	protein domain specific binding
0.36	GO:0005198	structural molecule activity

0.66	GO:0036126	sperm flagellum
0.55	GO:0044441	ciliary part
0.52	GO:0099513	polymeric cytoskeletal fiber
0.40	GO:0005581	collagen trimer
0.39	GO:0005576	extracellular region
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q8T414|Q8T414_DROME
AT22731p
Search

tr|Q8T415|Q8T415_DROME
AT22559p
Search

CETN2

0.65	Centrin, EF-hand protein, 2

0.41	GO:0007099	centriole replication
0.40	GO:0032465	regulation of cytokinesis
0.39	GO:0006289	nucleotide-excision repair
0.39	GO:0007283	spermatogenesis
0.36	GO:0022027	interkinetic nuclear migration
0.36	GO:0060271	cilium assembly
0.35	GO:0051301	cell division
0.34	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0034605	cellular response to heat

0.70	GO:0005509	calcium ion binding
0.45	GO:0032795	heterotrimeric G-protein binding
0.42	GO:0031683	G-protein beta/gamma-subunit complex binding
0.38	GO:0008017	microtubule binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.44	GO:0005814	centriole
0.43	GO:0071942	XPC complex
0.42	GO:0036064	ciliary basal body
0.41	GO:0032391	photoreceptor connecting cilium
0.40	GO:0005813	centrosome
0.34	GO:0030008	TRAPP complex
0.34	GO:0000922	spindle pole
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

GO:0032440

tr|Q8T419|Q8T419_DROME
AT21920p
Search

0.54

GO:0003677

DNA binding

0.30

GO:0044425

membrane part

tr|Q8T421|Q8T421_DROME
AT21561p
Search

tr|Q8T429|Q8T429_DROME
AT20289p
Search

0.92	Salivary expressed trypsin

0.61	GO:0006508	proteolysis
0.46	GO:0032504	multicellular organism reproduction
0.44	GO:0007620	copulation
0.43	GO:0051604	protein maturation
0.43	GO:0006898	receptor-mediated endocytosis
0.42	GO:0044706	multi-multicellular organism process
0.41	GO:0007610	behavior
0.40	GO:0006887	exocytosis
0.38	GO:0065008	regulation of biological quality
0.35	GO:0050817	coagulation

0.69	GO:0004252	serine-type endopeptidase activity
0.45	GO:0005044	scavenger receptor activity
0.36	GO:0008201	heparin binding
0.35	GO:0005509	calcium ion binding
0.32	GO:0008237	metallopeptidase activity
0.32	GO:0016301	kinase activity

0.44	GO:0005576	extracellular region
0.41	GO:0031410	cytoplasmic vesicle
0.41	GO:0030424	axon
0.40	GO:0043679	axon terminus
0.40	GO:0030425	dendrite
0.37	GO:0097223	sperm part
0.37	GO:0012505	endomembrane system
0.37	GO:0005886	plasma membrane
0.36	GO:0005766	primary lysosome
0.36	GO:0031983	vesicle lumen

0.69

GO:0004252

tr|Q8T452|Q8T452_DROME
AT16729p
Search

tr|Q8T465|Q8T465_DROME
AT13777p
Search

tr|Q8T481|Q8T481_DROME
AT11343p
Search

0.12	Tail-anchored protein insertion receptor WRB

0.85	GO:0071816	tail-anchored membrane protein insertion into ER membrane
0.73	GO:0048477	oogenesis
0.38	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation
0.38	GO:0032543	mitochondrial translation

0.37	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
0.37	GO:0004040	amidase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.37

EC:6.3.5.7

GO:0050567

tr|Q8T485|Q8T485_DROME
AT10995p
Search

0.50

GO:0055114

oxidation-reduction process

0.51

GO:0016491

oxidoreductase activity

0.51

GO:0016491

tr|Q8T490|Q8T490_DROME
Aminoacylase
Search

0.60	Aminoacylase

0.60	GO:0006520	cellular amino acid metabolic process
0.53	GO:0006508	proteolysis
0.33	GO:0008033	tRNA processing
0.33	GO:0030163	protein catabolic process
0.33	GO:0032259	methylation

0.85	GO:0004046	aminoacylase activity
0.58	GO:0008237	metallopeptidase activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.49	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus

0.85

EC:3.5.1.14

GO:0004046

sp|Q8T498|GAP2_DROME
Probable Ras GTPase-activating protein
Search

LOC108092777

0.86	probable Ras GTPase-activating protein isoform X7

0.75	GO:0043087	regulation of GTPase activity
0.72	GO:0051345	positive regulation of hydrolase activity
0.60	GO:0007165	signal transduction
0.40	GO:0046580	negative regulation of Ras protein signal transduction

0.73

GO:0005096

GTPase activator activity

0.39	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.39	GO:0045179	apical cortex
0.30	GO:0016021	integral component of membrane

tr|Q8T4A3|Q8T4A3_DROME
AT08308p
Search

0.48	Cyclin-dependent kinase 2

0.44

GO:0016310

phosphorylation

0.46

GO:0016301

kinase activity

tr|Q8T4A5|Q8T4A5_DROME
AT07857p
Search

TPK1

0.46	Thiamine pyrophosphokinase

0.75	GO:0042357	thiamine diphosphate metabolic process
0.72	GO:0006772	thiamine metabolic process
0.68	GO:0072528	pyrimidine-containing compound biosynthetic process
0.67	GO:0044272	sulfur compound biosynthetic process
0.65	GO:0009108	coenzyme biosynthetic process
0.61	GO:0090407	organophosphate biosynthetic process
0.54	GO:0019438	aromatic compound biosynthetic process
0.50	GO:0016310	phosphorylation
0.33	GO:0000413	protein peptidyl-prolyl isomerization

0.81	GO:0004788	thiamine diphosphokinase activity
0.81	GO:0030975	thiamine binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0016301	kinase activity
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.81

EC:2.7.6.2

GO:0004788

tr|Q8T4A8|Q8T4A8_DROME
AT07769p
Search

0.43	Chymotrypsin BI

0.61	GO:0006508	proteolysis
0.38	GO:0006898	receptor-mediated endocytosis
0.36	GO:0030574	collagen catabolic process
0.33	GO:0032504	multicellular organism reproduction
0.33	GO:0006030	chitin metabolic process
0.33	GO:0007620	copulation
0.33	GO:0002002	regulation of angiotensin levels in blood
0.33	GO:0009166	nucleotide catabolic process
0.32	GO:0044706	multi-multicellular organism process
0.32	GO:0007610	behavior

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005044	scavenger receptor activity
0.33	GO:0008061	chitin binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0016788	hydrolase activity, acting on ester bonds
0.32	GO:0016301	kinase activity
0.31	GO:1901265	nucleoside phosphate binding
0.31	GO:0036094	small molecule binding

0.36	GO:0005576	extracellular region
0.34	GO:0005581	collagen trimer
0.32	GO:0030141	secretory granule
0.30	GO:0016020	membrane

0.69

GO:0004252

tr|Q8T4A9|Q8T4A9_DROME
AT07738p
Search

0.61	Exosome component 9

0.62	GO:0006396	RNA processing
0.46	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process
0.46	GO:0071047	polyadenylation-dependent mRNA catabolic process
0.46	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process
0.46	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.45	GO:0071028	nuclear mRNA surveillance
0.45	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
0.45	GO:0016073	snRNA metabolic process
0.44	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0042254	ribosome biogenesis

0.46	GO:0017091	AU-rich element binding
0.42	GO:0004527	exonuclease activity
0.36	GO:0051082	unfolded protein binding
0.35	GO:0009022	tRNA nucleotidyltransferase activity
0.33	GO:0004519	endonuclease activity
0.32	GO:0000049	tRNA binding

0.79	GO:0000178	exosome (RNase complex)
0.41	GO:0031981	nuclear lumen
0.37	GO:0016272	prefoldin complex
0.37	GO:0044444	cytoplasmic part
0.34	GO:0043232	intracellular non-membrane-bounded organelle

0.35

EC:2.7.7.56

GO:0009022

tr|Q8T4B6|Q8T4B6_DROME
AT06885p
Search

STOM

0.59	Mechanosensory protein 2

0.41	GO:0007638	mechanosensory behavior
0.41	GO:1905792	positive regulation of mechanosensory behavior
0.41	GO:1905789	positive regulation of detection of mechanical stimulus involved in sensory perception of touch
0.40	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.35	GO:0006508	proteolysis
0.35	GO:1901585	regulation of acid-sensing ion channel activity
0.34	GO:0044829	positive regulation by host of viral genome replication
0.34	GO:0090314	positive regulation of protein targeting to membrane
0.34	GO:0051260	protein homooligomerization

0.39	GO:0015485	cholesterol binding
0.35	GO:0008233	peptidase activity
0.33	GO:0070063	RNA polymerase binding
0.33	GO:0042803	protein homodimerization activity

0.44	GO:0005887	integral component of plasma membrane
0.41	GO:0032589	neuron projection membrane
0.34	GO:0045121	membrane raft
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005856	cytoskeleton
0.32	GO:0005739	mitochondrion

0.35

GO:0008233

tr|Q8T4C4|Q8T4C4_DROME
ATP synthase subunit beta
Search

ATPD

0.43	ATP synthase subunit beta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.46	GO:0010155	regulation of proton transport
0.45	GO:0008340	determination of adult lifespan
0.45	GO:0048515	spermatid differentiation
0.33	GO:0048388	endosomal lumen acidification
0.32	GO:0003014	renal system process
0.32	GO:1902476	chloride transmembrane transport

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.32	GO:0005247	voltage-gated chloride channel activity

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0005886	plasma membrane
0.39	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.32	GO:0055037	recycling endosome
0.32	GO:0005769	early endosome
0.30	GO:0016021	integral component of membrane

tr|Q8T4C5|Q8T4C5_DROME
AT04450p
Search

0.39	GO:0055070	copper ion homeostasis
0.36	GO:0032259	methylation
0.35	GO:0016310	phosphorylation

0.49	GO:0016740	transferase activity
0.36	GO:0017022	myosin binding
0.35	GO:0016829	lyase activity

0.34	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0016740

tr|Q8T4C9|Q8T4C9_DROME
AT03632p
Search

0.47	Putative conserved protein with signal anchor

0.30

GO:0044425

membrane part

tr|Q8T4D4|Q8T4D4_DROME
AT03158p
Search

0.78	Testis-specific serine kinase

0.63	GO:0006468	protein phosphorylation
0.47	GO:0007286	spermatid development
0.41	GO:0007165	signal transduction
0.35	GO:0007275	multicellular organism development
0.34	GO:0030010	establishment of cell polarity
0.34	GO:0000226	microtubule cytoskeleton organization
0.33	GO:0043066	negative regulation of apoptotic process
0.33	GO:0018210	peptidyl-threonine modification
0.33	GO:0010133	proline catabolic process to glutamate
0.33	GO:0018209	peptidyl-serine modification

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding
0.33	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity
0.32	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0005509	calcium ion binding

0.44	GO:0001669	acrosomal vesicle
0.42	GO:0005814	centriole
0.42	GO:0031514	motile cilium
0.39	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004674

tr|Q8T4D6|Q8T4D6_DROME
Aconitate hydratase, mitochondrial
Search

0.69	Aconitate hydratase, mitochondrial

0.71	GO:0006099	tricarboxylic acid cycle
0.34	GO:0032504	multicellular organism reproduction
0.33	GO:0007165	signal transduction

0.79	GO:0003994	aconitate hydratase activity
0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.33	GO:0003924	GTPase activity
0.33	GO:0001883	purine nucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032549	ribonucleoside binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032555	purine ribonucleotide binding

0.59	GO:0005739	mitochondrion
0.34	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.79

EC:4.2.1.3

GO:0003994

tr|Q8T4D9|Q8T4D9_DROME
AT02704p
Search

sp|Q8T4E1|GPI8_DROME
Putative GPI-anchor transamidase
Search

0.56	Phosphatidylinositol glycan

0.82	GO:0016255	attachment of GPI anchor to protein
0.61	GO:0006508	proteolysis
0.47	GO:0034394	protein localization to cell surface
0.41	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.35	GO:0006030	chitin metabolic process
0.34	GO:0034968	histone lysine methylation
0.33	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0034220	ion transmembrane transport

0.85	GO:0003923	GPI-anchor transamidase activity
0.61	GO:0008233	peptidase activity
0.35	GO:0008061	chitin binding
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0005216	ion channel activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0003677	DNA binding

0.81	GO:0042765	GPI-anchor transamidase complex
0.34	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.33	GO:0005694	chromosome
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.85

GO:0003923

tr|Q8T4E7|Q8T4E7_DROME
AT02038p
Search

0.82	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.71	GO:0016567	protein ubiquitination
0.41	GO:0006468	protein phosphorylation

0.71	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0004672	protein kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0019005	SCF ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0004842

tr|Q8T4F2|Q8T4F2_DROME
AT01806p
Search

0.55	Mitochondrial outer membrane protein metaxin 2 metaxin 1-binding protein

0.79

GO:0006626

protein targeting to mitochondrion

0.35	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0005741	mitochondrial outer membrane
0.34	GO:0005730	nucleolus

sp|Q8T4F7|ENA_DROME
Protein enabled
Search

0.84	GO:0007396	suture of dorsal opening
0.82	GO:0060288	formation of a compartment boundary
0.81	GO:1990255	subsynaptic reticulum organization
0.80	GO:0007303	cytoplasmic transport, nurse cell to oocyte
0.79	GO:0007390	germ-band shortening
0.78	GO:0035262	gonad morphogenesis
0.77	GO:0008258	head involution
0.77	GO:0046847	filopodium assembly
0.77	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.76	GO:0010591	regulation of lamellipodium assembly

0.70	GO:0017124	SH3 domain binding
0.43	GO:0003779	actin binding

0.80	GO:0071212	subsynaptic reticulum
0.77	GO:0032433	filopodium tip
0.72	GO:0030027	lamellipodium
0.70	GO:0030425	dendrite
0.69	GO:0005912	adherens junction
0.67	GO:0005911	cell-cell junction
0.61	GO:0005829	cytosol
0.42	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

tr|Q8T4G5|Q8T4G5_DROME
CG6512, isoform A
Search

0.75	Paraplegin

0.61

GO:0006508

proteolysis

0.70	GO:0004222	metalloendopeptidase activity
0.61	GO:0008270	zinc ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|Q8T4G7|Q8T4G7_DROME
AT13439p
Search

0.30

GO:0044425

membrane part

tr|Q8T4H6|Q8T4H6_DROME
AT08210p
Search

tr|Q8T4H8|Q8T4H8_DROME
AT07685p
Search

0.48	Cytochrome c oxidase polypeptide IV

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.38	GO:0006119	oxidative phosphorylation
0.38	GO:0009060	aerobic respiration
0.36	GO:0006508	proteolysis

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.37	GO:0004175	endopeptidase activity
0.36	GO:0017171	serine hydrolase activity
0.36	GO:0008234	cysteine-type peptidase activity
0.34	GO:0016874	ligase activity

0.42	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

tr|Q8T4I0|Q8T4I0_DROME
AT07524p
Search

0.53	Ketohexokinase

0.81	GO:0006000	fructose metabolic process
0.73	GO:0046835	carbohydrate phosphorylation
0.43	GO:0019303	D-ribose catabolic process

0.86	GO:0004454	ketohexokinase activity
0.43	GO:0004747	ribokinase activity
0.42	GO:0008865	fructokinase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008144	drug binding
0.36	GO:0046872	metal ion binding

0.36	GO:0005737	cytoplasm
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.7.1.3

GO:0004454

tr|Q8T4I5|Q8T4I5_DROME
AT04449p
Search

0.30

GO:0044425

membrane part

tr|Q8T5S8|Q8T5S8_DROME
FI23978p1
Search

0.47	Prolyl 4-hydroxylase subunit alpha-2

0.82	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0032504	multicellular organism reproduction

0.83	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.73	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.63	GO:0005506	iron ion binding

0.68	GO:0005783	endoplasmic reticulum
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005576	extracellular region
0.32	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.83	EC:1.14.11.2	GO:0004656
0.83	KEGG:R03219	GO:0004656

sp|Q8T626|DLT_DROME
Protein disks lost
Search

0.85	GO:0042048	olfactory behavior
0.83	GO:0007560	imaginal disc morphogenesis
0.76	GO:0042127	regulation of cell proliferation
0.50	GO:0001738	morphogenesis of a polarized epithelium

0.35

GO:0005509

calcium ion binding

0.49

GO:0005737

cytoplasm

sp|Q8T6B9|PUF68_DROME
Poly(U)-binding-splicing factor half pint
Search

0.68	Poly(U)-binding-splicing factor half pint

0.59	GO:0007282	cystoblast division
0.58	GO:0000380	alternative mRNA splicing, via spliceosome
0.56	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.55	GO:0006376	mRNA splice site selection
0.55	GO:0045926	negative regulation of growth
0.54	GO:0001558	regulation of cell growth
0.53	GO:0008285	negative regulation of cell proliferation
0.37	GO:0048477	oogenesis
0.35	GO:0007275	multicellular organism development

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.45	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.34	GO:1902494	catalytic complex
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0044446	intracellular organelle part

sp|Q8T8L8|ALG10_DROME
Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
Search

ALG10

0.79	Alpha-1,2-glucosyltransferase

0.83	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.45	GO:0006487	protein N-linked glycosylation
0.43	GO:0048366	leaf development
0.43	GO:0009651	response to salt stress
0.34	GO:0060117	auditory receptor cell development
0.34	GO:0007605	sensory perception of sound
0.32	GO:0055114	oxidation-reduction process

0.85	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
0.40	GO:0106073	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

GO:0004583

sp|Q8T8R1|Y3800_DROME
CCHC-type zinc finger protein CG3800
Search

0.42	DNA-binding protein HEXBP

0.40	GO:0032259	methylation
0.37	GO:2000767	positive regulation of cytoplasmic translation
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0006182	cGMP biosynthetic process
0.32	GO:0006413	translational initiation
0.32	GO:0035556	intracellular signal transduction

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.45	GO:0016874	ligase activity
0.40	GO:0005201	extracellular matrix structural constituent
0.40	GO:0008168	methyltransferase activity
0.37	GO:0004930	G-protein coupled receptor activity
0.36	GO:0045182	translation regulator activity
0.33	GO:0004383	guanylate cyclase activity
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding

0.39	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0042788	polysomal ribosome
0.36	GO:0000932	P-body
0.36	GO:0010494	cytoplasmic stress granule
0.34	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

0.45

GO:0016874

tr|Q8T8R6|Q8T8R6_DROME
AT31822p
Search

0.43	GO:0030150	protein import into mitochondrial matrix
0.41	GO:0048666	neuron development
0.41	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0044085	cellular component biogenesis
0.40	GO:0060042	retina morphogenesis in camera-type eye
0.40	GO:0035553	oxidative single-stranded RNA demethylation
0.40	GO:0001754	eye photoreceptor cell differentiation
0.40	GO:0098840	protein transport along microtubule
0.40	GO:0019538	protein metabolic process
0.40	GO:0031503	protein complex localization

0.42	GO:0051087	chaperone binding
0.41	GO:1901265	nucleoside phosphate binding
0.41	GO:0036094	small molecule binding
0.40	GO:0035515	oxidative RNA demethylase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0008270	zinc ion binding
0.38	GO:0003676	nucleic acid binding
0.37	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0003713	transcription coactivator activity

0.40	GO:0032391	photoreceptor connecting cilium
0.40	GO:0001750	photoreceptor outer segment
0.40	GO:0036126	sperm flagellum
0.40	GO:0036064	ciliary basal body
0.39	GO:0005813	centrosome
0.39	GO:0097361	CIA complex
0.39	GO:0005883	neurofilament
0.38	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0009425	bacterial-type flagellum basal body
0.37	GO:0012505	endomembrane system

0.37

EC:2.7

GO:0016772

tr|Q8T8R7|Q8T8R7_DROME
AT31812p
Search

0.30

GO:0044425

membrane part

tr|Q8T8S1|Q8T8S1_DROME
Defective in cullin neddylation protein
Search

0.62	Defective in cullin neddylation protein (Fragment)

0.83	GO:2000436	positive regulation of protein neddylation
0.61	GO:0010225	response to UV-C
0.60	GO:0030308	negative regulation of cell growth
0.59	GO:0010332	response to gamma radiation
0.58	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.58	GO:0043065	positive regulation of apoptotic process
0.54	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.51	GO:0045116	protein neddylation
0.38	GO:0045905	positive regulation of translational termination
0.38	GO:0045901	positive regulation of translational elongation

0.57	GO:0097602	cullin family protein binding
0.56	GO:0031624	ubiquitin conjugating enzyme binding
0.53	GO:0032182	ubiquitin-like protein binding
0.36	GO:0043022	ribosome binding
0.36	GO:0003746	translation elongation factor activity
0.34	GO:0016491	oxidoreductase activity
0.33	GO:0016787	hydrolase activity

0.58	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0000151	ubiquitin ligase complex
0.51	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0016491

tr|Q8T8S2|Q8T8S2_DROME
Uridine phosphorylase
Search

0.48	Uridine phosphorylase

0.75	GO:0009166	nucleotide catabolic process
0.66	GO:0009116	nucleoside metabolic process
0.57	GO:0032262	pyrimidine nucleotide salvage
0.53	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process
0.52	GO:0009218	pyrimidine ribonucleotide metabolic process
0.51	GO:1901659	glycosyl compound biosynthetic process
0.49	GO:0009260	ribonucleotide biosynthetic process
0.44	GO:0042332	gravitaxis
0.34	GO:0006000	fructose metabolic process
0.33	GO:0046835	carbohydrate phosphorylation

0.82	GO:0004850	uridine phosphorylase activity
0.34	GO:0004454	ketohexokinase activity
0.33	GO:0031418	L-ascorbic acid binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0005506	iron ion binding

0.49	GO:0005737	cytoplasm
0.33	GO:0048475	coated membrane
0.32	GO:0098796	membrane protein complex

0.82

EC:2.4.2.3

GO:0004850

tr|Q8T8S5|Q8T8S5_DROME
AT30929p
Search

tr|Q8T8T9|Q8T8T9_DROME
AT30094p
Search

0.80	Presqualene diphosphate phosphatase

0.33	GO:0098869	cellular oxidant detoxification
0.32	GO:0006796	phosphate-containing compound metabolic process

0.33	GO:0004601	peroxidase activity
0.33	GO:0003951	NAD+ kinase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003993	acid phosphatase activity

0.32	GO:0030288	outer membrane-bounded periplasmic space
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:1.11.1.7	GO:0004601
0.33	KEGG:R03532	GO:0004601

tr|Q8T8U1|Q8T8U1_DROME
Proteasome subunit beta type
Search

0.45	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.46	GO:0043632	modification-dependent macromolecule catabolic process

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0016887	ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm

0.34

GO:0016887

tr|Q8T8W0|Q8T8W0_DROME
AT21693p
Search

0.10	DNA polymerase zeta processivity subunit

tr|Q8T8W2|Q8T8W2_DROME
AT21555p
Search

0.83	N-methyl-D-aspartate receptor glutamate-binding subunit

0.40	GO:0005544	calcium-dependent phospholipid binding
0.38	GO:0005509	calcium ion binding

0.30

GO:0044425

membrane part

tr|Q8T8W3|Q8T8W3_DROME
AT21416p
Search

0.66	EH domain-containing protein 1, membrane trafficking

0.77	GO:0032456	endocytic recycling
0.50	GO:1990255	subsynaptic reticulum organization
0.48	GO:0048052	R1/R6 cell differentiation
0.48	GO:0007291	sperm individualization
0.48	GO:0007474	imaginal disc-derived wing vein specification
0.48	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.47	GO:0042670	retinal cone cell differentiation
0.47	GO:0045466	R7 cell differentiation
0.46	GO:0048477	oogenesis
0.43	GO:0060990	lipid tube assembly involved in organelle fission

0.66	GO:0005509	calcium ion binding
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0019904	protein domain specific binding
0.36	GO:0016887	ATPase activity

0.49	GO:0071212	subsynaptic reticulum
0.40	GO:0055037	recycling endosome
0.35	GO:0010008	endosome membrane

0.36

GO:0016887

tr|Q8T8W6|Q8T8W6_DROME
Phosphoglycerate mutase
Search

0.46	Phosphoglycerate mutase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.53	GO:0019319	hexose biosynthetic process
0.52	GO:0006006	glucose metabolic process
0.40	GO:0043456	regulation of pentose-phosphate shunt

0.78	GO:0004619	phosphoglycerate mutase activity
0.76	GO:0004082	bisphosphoglycerate mutase activity

0.36	GO:0005829	cytosol
0.34	GO:0009277	fungal-type cell wall

0.78

EC:5.4.2.1

GO:0004619

tr|Q8T8Y5|Q8T8Y5_DROME
AT16536p
Search

0.88	Proapoptotic Bcl-2 family protein Debcl

0.74	GO:0042981	regulation of apoptotic process
0.61	GO:0035234	ectopic germ cell programmed cell death
0.58	GO:0016239	positive regulation of macroautophagy
0.55	GO:0009267	cellular response to starvation
0.55	GO:0043069	negative regulation of programmed cell death
0.52	GO:0043068	positive regulation of programmed cell death
0.47	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.46	GO:0060561	apoptotic process involved in morphogenesis
0.46	GO:0070050	neuron cellular homeostasis
0.44	GO:1901215	negative regulation of neuron death

0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005783	endoplasmic reticulum
0.40	GO:0005740	mitochondrial envelope
0.40	GO:0031968	organelle outer membrane
0.30	GO:0016021	integral component of membrane

tr|Q8T8Y8|Q8T8Y8_DROME
AT15826p
Search

tr|Q8T8Z2|Q8T8Z2_DROME
AT14535p
Search

0.66	polycystic kidney disease protein 1-like 3

0.78	GO:0050960	detection of temperature stimulus involved in thermoception
0.74	GO:0009409	response to cold
0.55	GO:0033554	cellular response to stress
0.52	GO:0070588	calcium ion transmembrane transport
0.48	GO:0050982	detection of mechanical stimulus
0.35	GO:0016311	dephosphorylation

0.70	GO:0005509	calcium ion binding
0.53	GO:0005262	calcium channel activity
0.37	GO:0003993	acid phosphatase activity

0.30

GO:0031224

intrinsic component of membrane

0.37

EC:3.1.3.2

GO:0003993

tr|Q8T908|Q8T908_DROME
AT12868p
Search

tr|Q8T913|Q8T913_DROME
AT07283p
Search

FANCL

0.60	E3 ubiquitin-protein ligase FANCL

0.76	GO:0006513	protein monoubiquitination
0.65	GO:0006281	DNA repair

0.74	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0016874	ligase activity
0.36	GO:0046872	metal ion binding

0.85

GO:0043240

Fanconi anaemia nuclear complex

0.40	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|Q8T915|Q8T915_DROME
AT05866p
Search

0.12	proteasome subunit beta type-7

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.50	GO:0043632	modification-dependent macromolecule catabolic process

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.76	GO:0005839	proteasome core complex
0.46	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

tr|Q8T956|Q8T956_DROME
AT29956p
Search

tr|Q8T959|Q8T959_DROME
AT26083p
Search

0.86	male-specific sperm protein Mst84Db

tr|Q8T965|Q8T965_DROME
Prefoldin subunit 3
Search

0.40	Prefoldin subunit 3

0.69	GO:0006457	protein folding
0.56	GO:0007021	tubulin complex assembly
0.50	GO:0007017	microtubule-based process

0.51

GO:0015631

tubulin binding

0.80	GO:0016272	prefoldin complex
0.55	GO:0005844	polysome
0.39	GO:0005737	cytoplasm

tr|Q8T969|Q8T969_DROME
AT21341p
Search

tr|Q8T975|Q8T975_DROME
AT18358p
Search

0.30

GO:0044425

membrane part

tr|Q8T983|Q8T983_DROME
AT08725p
Search

0.12	outer dense fiber protein 3-B

sp|Q8T9B6|MESD_DROME
LDLR chaperone boca
Search

0.82	Chaperone for wingless signaling and trafficking of LDL receptor

0.69	GO:0006457	protein folding
0.45	GO:0006888	ER to Golgi vesicle-mediated transport
0.44	GO:0006612	protein targeting to membrane
0.36	GO:0016925	protein sumoylation
0.35	GO:0032981	mitochondrial respiratory chain complex I assembly
0.35	GO:0016055	Wnt signaling pathway
0.34	GO:0008033	tRNA processing
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.44	GO:0042802	identical protein binding
0.36	GO:0019789	SUMO transferase activity
0.34	GO:0016783	sulfurtransferase activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005788	endoplasmic reticulum lumen
0.46	GO:0045177	apical part of cell
0.30	GO:0016020	membrane

0.34

EC:2.8.1

GO:0016783

tr|Q8T9E6|Q8T9E6_DROME
SD03967p
Search

0.38	ABC-2 type transporter

0.53	GO:0006641	triglyceride metabolic process
0.41	GO:0030301	cholesterol transport

0.60	GO:0016887	ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0017127	cholesterol transporter activity
0.40	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.37	GO:0015399	primary active transmembrane transporter activity

0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.60

GO:0016887

tr|Q8T9E9|Q8T9E9_DROME
SD03580p
Search

tr|Q8T9G7|Q8T9G7_DROME
SD01558p
Search

0.40	alpha-tocopherol transfer protein isoform X1

0.62	GO:0031210	phosphatidylcholine binding
0.55	GO:0035091	phosphatidylinositol binding
0.48	GO:0016787	hydrolase activity

0.47

GO:0005634

nucleus

0.48

GO:0016787

tr|Q8T9H8|Q8T9H8_DROME
GM14337p
Search

0.10	enhancer of mRNA-decapping protein 1

0.45	GO:0009113	purine nucleobase biosynthetic process
0.44	GO:0006189	'de novo' IMP biosynthetic process
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.40	GO:0048518	positive regulation of biological process
0.40	GO:0016310	phosphorylation
0.39	GO:0061328	posterior Malpighian tubule development
0.38	GO:0051276	chromosome organization
0.38	GO:0035212	cell competition in a multicellular organism

0.46	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity
0.46	GO:0004637	phosphoribosylamine-glycine ligase activity
0.46	GO:0004644	phosphoribosylglycinamide formyltransferase activity
0.42	GO:0046872	metal ion binding
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0043565	sequence-specific DNA binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008144	drug binding
0.41	GO:0140110	transcription regulator activity

0.45	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.37	GO:1990234	transferase complex
0.35	GO:0005694	chromosome
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.46	EC:6.3.3.1	GO:0004641
0.46	KEGG:R04208	GO:0004641

tr|Q8T9L5|Q8T9L5_DROME
GM01569p
Search

STK11

0.37	Serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.53	GO:0007163	establishment or maintenance of cell polarity
0.52	GO:0030709	border follicle cell delamination
0.51	GO:0007399	nervous system development
0.51	GO:0045451	pole plasm oskar mRNA localization
0.51	GO:0001932	regulation of protein phosphorylation
0.50	GO:0072697	protein localization to cell cortex
0.50	GO:0036445	neuronal stem cell division
0.50	GO:1902531	regulation of intracellular signal transduction
0.50	GO:0098722	asymmetric stem cell division

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0030295	protein kinase activator activity
0.48	GO:0030275	LRR domain binding
0.47	GO:0002039	p53 binding
0.40	GO:0000287	magnesium ion binding
0.34	GO:0019901	protein kinase binding

0.49	GO:0036398	TCR signalosome
0.46	GO:0005938	cell cortex
0.45	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0005739	mitochondrion
0.39	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|Q8WS79|Q8WS79_DROME
Estrogen-related receptor splice variant
Search

0.88	Steroid hormone receptor ERR2

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0007283	spermatogenesis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0005975	carbohydrate metabolic process
0.41	GO:0030522	intracellular receptor signaling pathway
0.33	GO:0045454	cell redox homeostasis
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0005496	steroid binding
0.80	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016491

sp|Q8WSF3|FDL_DROME
Probable beta-hexosaminidase fdl
Search

0.46	Beta-hexosaminidase fdl

0.60	GO:0005975	carbohydrate metabolic process
0.53	GO:0016063	rhodopsin biosynthetic process
0.51	GO:0006517	protein deglycosylation
0.50	GO:0006491	N-glycan processing
0.48	GO:0007420	brain development
0.40	GO:0044130	negative regulation of growth of symbiont in host
0.36	GO:0006032	chitin catabolic process
0.33	GO:0007166	cell surface receptor signaling pathway
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0032504	multicellular organism reproduction

0.79	GO:0004563	beta-N-acetylhexosaminidase activity
0.75	GO:0102148	N-acetyl-beta-D-galactosaminidase activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0043565	sequence-specific DNA binding

0.49	GO:0005770	late endosome
0.45	GO:0005794	Golgi apparatus
0.45	GO:0005783	endoplasmic reticulum
0.41	GO:0005886	plasma membrane
0.33	GO:0005615	extracellular space
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.79

EC:3.2.1.52

GO:0004563

sp|Q8WTC1|RT15_DROME
28S ribosomal protein S15, mitochondrial
Search

0.63	28s ribosomal protein mitochondrial

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0040008	regulation of growth

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005840	ribosome
0.45	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q8WTI6|Q8WTI6_DROME
PFTAIRE-interacting factor 2
Search

0.41	PFTAIRE-interacting factor 2

0.41	GO:0007283	spermatogenesis
0.39	GO:0030154	cell differentiation
0.39	GO:0007017	microtubule-based process
0.39	GO:0007275	multicellular organism development
0.39	GO:0006928	movement of cell or subcellular component
0.37	GO:0008544	epidermis development
0.37	GO:0060271	cilium assembly
0.37	GO:0022412	cellular process involved in reproduction in multicellular organism
0.37	GO:0003006	developmental process involved in reproduction
0.36	GO:0060429	epithelium development

0.44	GO:0005515	protein binding
0.38	GO:0003777	microtubule motor activity
0.34	GO:0005198	structural molecule activity

0.71	GO:0045095	keratin filament
0.39	GO:0036126	sperm flagellum
0.35	GO:0005829	cytosol
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q94511|NDUS1_DROME
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Search

0.44	NADH-ubiquinone oxidoreductase subunit A

0.69	GO:0042773	ATP synthesis coupled electron transport
0.42	GO:0008637	apoptotic mitochondrial changes
0.36	GO:0072593	reactive oxygen species metabolic process
0.36	GO:0051881	regulation of mitochondrial membrane potential
0.34	GO:0032784	regulation of DNA-templated transcription, elongation
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.64	GO:0051536	iron-sulfur cluster binding
0.61	GO:0009055	electron transfer activity
0.35	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.43	GO:0045272	plasma membrane respiratory chain complex I
0.41	GO:0005747	mitochondrial respiratory chain complex I
0.35	GO:0043209	myelin sheath
0.35	GO:0005758	mitochondrial intermembrane space
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:1.6.5.3

GO:0008137

sp|Q94514|COX5A_DROME
Cytochrome c oxidase subunit 5A, mitochondrial
Search

0.77	Mitochondrial cytochrome c oxidase subunit Va

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.50	GO:0007406	negative regulation of neuroblast proliferation
0.47	GO:0045787	positive regulation of cell cycle
0.36	GO:0006119	oxidative phosphorylation
0.36	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.33	GO:0046872	metal ion binding
0.31	GO:0003676	nucleic acid binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.38	GO:0045277	respiratory chain complex IV
0.38	GO:0098798	mitochondrial protein complex
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

tr|Q94515|Q94515_DROME
Des-1 protein
Search

0.40	Fatty acid desaturase

0.81	GO:0030148	sphingolipid biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.49	GO:0007053	spindle assembly involved in male meiosis
0.42	GO:0006672	ceramide metabolic process
0.37	GO:0043604	amide biosynthetic process
0.35	GO:0007283	spermatogenesis

0.84	GO:0042284	sphingolipid delta-4 desaturase activity
0.34	GO:0019706	protein-cysteine S-palmitoyltransferase activity

0.48	GO:0016006	Nebenkern
0.46	GO:0070938	contractile ring
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:2.3.1.225

GO:0019706

sp|Q94516|AT5F1_DROME
ATP synthase subunit b, mitochondrial
Search

0.40	Mitochondrial ATP synthase subunit b

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.37	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.36	GO:0050909	sensory perception of taste
0.34	GO:0007165	signal transduction
0.33	GO:0006518	peptide metabolic process
0.33	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.37	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.37	GO:0019829	cation-transporting ATPase activity
0.34	GO:0004871	signal transducer activity
0.33	GO:0003735	structural constituent of ribosome

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0005761	mitochondrial ribosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q94517|HDAC1_DROME
Histone deacetylase Rpd3
Search

RPD3

0.51	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.48	GO:2001229	negative regulation of response to gamma radiation
0.47	GO:0061086	negative regulation of histone H3-K27 methylation
0.47	GO:0070983	dendrite guidance
0.46	GO:0045879	negative regulation of smoothened signaling pathway
0.46	GO:1902692	regulation of neuroblast proliferation

0.81	GO:0004407	histone deacetylase activity
0.74	GO:0034979	NAD-dependent protein deacetylase activity
0.53	GO:0046872	metal ion binding
0.44	GO:0003714	transcription corepressor activity
0.42	GO:0051059	NF-kappaB binding
0.42	GO:0001103	RNA polymerase II repressing transcription factor binding
0.41	GO:0042826	histone deacetylase binding
0.37	GO:0043565	sequence-specific DNA binding

0.58	GO:0005634	nucleus
0.48	GO:0017053	transcriptional repressor complex
0.47	GO:0031523	Myb complex
0.46	GO:0005705	polytene chromosome interband
0.46	GO:0034708	methyltransferase complex
0.45	GO:0000785	chromatin
0.43	GO:0031974	membrane-enclosed lumen
0.43	GO:1904949	ATPase complex
0.34	GO:0005737	cytoplasm

0.81

EC:3.5.1.98

GO:0004407

sp|Q94518|NACA_DROME
Nascent polypeptide-associated complex subunit alpha
Search

0.60	Nascent polypeptide associated complex protein alpha subunit

0.46	GO:0048477	oogenesis
0.36	GO:0070588	calcium ion transmembrane transport
0.35	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.34	GO:0015031	protein transport
0.34	GO:0030239	myofibril assembly
0.34	GO:0007275	multicellular organism development
0.33	GO:0007018	microtubule-based movement

0.36	GO:0005388	calcium-transporting ATPase activity
0.34	GO:0005515	protein binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.84	GO:0005854	nascent polypeptide-associated complex
0.33	GO:0016459	myosin complex
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.36

EC:3.6.3.8

GO:0005388

sp|Q94519|ACPM_DROME
Acyl carrier protein, mitochondrial
Search

0.46	Acyl carrier protein, mitochondrial

0.70	GO:0006633	fatty acid biosynthetic process
0.38	GO:0009245	lipid A biosynthetic process
0.36	GO:0032981	mitochondrial respiratory chain complex I assembly
0.35	GO:0006338	chromatin remodeling
0.35	GO:0009249	protein lipoylation
0.35	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.41	GO:0000035	acyl binding
0.39	GO:0000036	acyl carrier activity
0.38	GO:0031177	phosphopantetheine binding
0.35	GO:0042393	histone binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0016887	ATPase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005829	cytosol
0.36	GO:0031981	nuclear lumen
0.35	GO:0005747	mitochondrial respiratory chain complex I
0.34	GO:0000785	chromatin
0.34	GO:1904949	ATPase complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0016887

sp|Q94521|DNAT_DROME
Dopamine N-acetyltransferase
Search

0.40	Dopamine N-acetyltransferase

0.64	GO:0006584	catecholamine metabolic process
0.44	GO:0046334	octopamine catabolic process
0.43	GO:0042429	serotonin catabolic process
0.42	GO:0030187	melatonin biosynthetic process
0.41	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.41	GO:0030431	sleep
0.41	GO:0048066	developmental pigmentation
0.40	GO:0019614	catechol-containing compound catabolic process
0.38	GO:0042737	drug catabolic process

0.66	GO:0004059	aralkylamine N-acetyltransferase activity
0.66	GO:0004060	arylamine N-acetyltransferase activity

0.41	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.66

EC:2.3.1.87

GO:0004059

sp|Q94522|SUCA_DROME
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
Search

0.88	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

0.67	GO:0006099	tricarboxylic acid cycle
0.48	GO:0061621	canonical glycolysis
0.35	GO:0006104	succinyl-CoA metabolic process
0.34	GO:0006030	chitin metabolic process
0.34	GO:0006518	peptide metabolic process
0.34	GO:0043604	amide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:1901566	organonitrogen compound biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.81	GO:0004776	succinate-CoA ligase (GDP-forming) activity
0.73	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.55	GO:0048037	cofactor binding
0.50	GO:1901265	nucleoside phosphate binding
0.49	GO:0004778	succinyl-CoA hydrolase activity
0.49	GO:0036094	small molecule binding
0.37	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0019843	rRNA binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0008061	chitin binding

0.58	GO:0005739	mitochondrion
0.36	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0042709	succinate-CoA ligase complex
0.36	GO:0005829	cytosol
0.34	GO:0031090	organelle membrane
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0031975	envelope
0.34	GO:0005886	plasma membrane
0.34	GO:0030529	intracellular ribonucleoprotein complex

0.81	EC:6.2.1.4	GO:0004776
0.81	KEGG:R00432	GO:0004776

sp|Q94523|SDHA_DROME
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Search

0.49	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.42	GO:0006105	succinate metabolic process
0.40	GO:0009061	anaerobic respiration
0.40	GO:0007399	nervous system development
0.38	GO:0006119	oxidative phosphorylation

0.78	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0009055	electron transfer activity

0.59	GO:0031966	mitochondrial membrane
0.59	GO:0019866	organelle inner membrane
0.44	GO:0045282	plasma membrane succinate dehydrogenase complex
0.43	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.43	GO:0045283	fumarate reductase complex
0.41	GO:0043209	myelin sheath
0.40	GO:0098798	mitochondrial protein complex
0.39	GO:0005730	nucleolus

0.78	EC:1.3.5.1	GO:0008177
0.78	KEGG:R02164	GO:0008177

sp|Q94524|DYLT_DROME
Dynein light chain Tctex-type
Search

0.64	Dynein light chain Tctex-type

0.77	GO:0019060	intracellular transport of viral protein in host cell
0.65	GO:0008090	retrograde axonal transport
0.62	GO:0008340	determination of adult lifespan
0.61	GO:0007286	spermatid development
0.47	GO:0000132	establishment of mitotic spindle orientation
0.46	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.46	GO:0050768	negative regulation of neurogenesis
0.44	GO:0010976	positive regulation of neuron projection development
0.44	GO:1905709	negative regulation of membrane permeability
0.44	GO:0035022	positive regulation of Rac protein signal transduction

0.73	GO:0042802	identical protein binding
0.64	GO:0051959	dynein light intermediate chain binding
0.64	GO:0097718	disordered domain specific binding
0.63	GO:0045505	dynein intermediate chain binding
0.53	GO:0046983	protein dimerization activity
0.45	GO:0003774	motor activity
0.42	GO:0008022	protein C-terminus binding
0.39	GO:0031681	G-protein beta-subunit binding
0.39	GO:0030742	GTP-dependent protein binding
0.36	GO:0042623	ATPase activity, coupled

0.78	GO:0030286	dynein complex
0.73	GO:0005881	cytoplasmic microtubule
0.69	GO:0099503	secretory vesicle
0.63	GO:1904115	axon cytoplasm
0.56	GO:0043657	host cell
0.44	GO:0030426	growth cone
0.44	GO:0005819	spindle
0.43	GO:0044297	cell body
0.43	GO:0005794	Golgi apparatus
0.42	GO:0030027	lamellipodium

sp|Q94526|ORK1_DROME
Open rectifier potassium channel protein 1
Search

ORK1

0.90	Open rectifier potassium channel protein 1

0.72	GO:0071805	potassium ion transmembrane transport
0.44	GO:0030322	stabilization of membrane potential
0.41	GO:0045475	locomotor rhythm
0.41	GO:0002027	regulation of heart rate
0.32	GO:0006508	proteolysis
0.32	GO:0008610	lipid biosynthetic process
0.31	GO:0055114	oxidation-reduction process

0.75	GO:0005267	potassium channel activity
0.44	GO:0022842	narrow pore channel activity
0.39	GO:0042803	protein homodimerization activity
0.36	GO:0004386	helicase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004252	serine-type endopeptidase activity
0.31	GO:0016491	oxidoreductase activity

0.39	GO:0034705	potassium channel complex
0.39	GO:0005887	integral component of plasma membrane

0.33

GO:0004252

sp|Q94527|NFKB1_DROME
Nuclear factor NF-kappa-B p110 subunit
Search

0.81	Nuclear factor NF-kappa-B p110 subunit

0.73	GO:0002810	regulation of antifungal peptide biosynthetic process
0.73	GO:0002804	positive regulation of antifungal peptide production
0.72	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.71	GO:0061057	peptidoglycan recognition protein signaling pathway
0.70	GO:2000647	negative regulation of stem cell proliferation
0.70	GO:0048935	peripheral nervous system neuron development
0.69	GO:0002230	positive regulation of defense response to virus by host
0.69	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.68	GO:0034198	cellular response to amino acid starvation
0.67	GO:0048813	dendrite morphogenesis

0.65	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.41	GO:0008134	transcription factor binding
0.37	GO:0003682	chromatin binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0042802	identical protein binding
0.34	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity

0.68	GO:0005719	nuclear euchromatin
0.49	GO:0005737	cytoplasm
0.39	GO:0033256	I-kappaB/NF-kappaB complex
0.36	GO:0005654	nucleoplasm
0.34	GO:1905369	endopeptidase complex

0.34	EC:1.5.1.5	GO:0004488
0.34	KEGG:R01220	GO:0004488

sp|Q94529|GS1_DROME
Probable pseudouridine-5'-phosphatase
Search

0.81	Haloacid dehalogenase hydrolase domain-containing protein 1A

0.41	GO:0016311	dephosphorylation
0.36	GO:0006114	glycerol biosynthetic process
0.36	GO:0042060	wound healing
0.34	GO:0009117	nucleotide metabolic process
0.34	GO:0043097	pyrimidine nucleoside salvage
0.32	GO:0016310	phosphorylation

0.51	GO:0016787	hydrolase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0008531	riboflavin kinase activity
0.33	GO:0003676	nucleic acid binding

0.36	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.51	EC:3	GO:0016787
0.34	KEGG:R00549	GO:0008531

tr|Q94533|Q94533_DROME
Ribosomal protein S6 kinase
Search

0.65	Ribosomal protein S6 kinase beta-1

0.63	GO:0006468	protein phosphorylation
0.58	GO:0007165	signal transduction
0.50	GO:0016239	positive regulation of macroautophagy
0.50	GO:0030536	larval feeding behavior
0.50	GO:0008340	determination of adult lifespan
0.50	GO:2000331	regulation of terminal button organization
0.49	GO:0051124	synaptic growth at neuromuscular junction
0.49	GO:0045793	positive regulation of cell size
0.49	GO:0007525	somatic muscle development
0.48	GO:0007520	myoblast fusion

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.47	GO:0048786	presynaptic active zone
0.37	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0005840	ribosome
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043204	perikaryon
0.34	GO:0030424	axon

0.70

GO:0004674

sp|Q94535|U2AF1_DROME
Splicing factor U2af 38 kDa subunit
Search

0.86	U2 small nuclear riboprotein auxiliary factor 38, isoform B

0.75	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.35	GO:0050733	RS domain binding

0.84	GO:0089701	U2AF
0.39	GO:0005681	spliceosomal complex
0.34	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

sp|Q94545|ASH2_DROME
Set1/Ash2 histone methyltransferase complex subunit ASH2
Search

0.78	Absent small or homeotic discs 2

0.83	GO:0051568	histone H3-K4 methylation
0.50	GO:0033128	negative regulation of histone phosphorylation
0.50	GO:0035209	pupal development
0.49	GO:0048096	chromatin-mediated maintenance of transcription
0.49	GO:0007474	imaginal disc-derived wing vein specification
0.49	GO:0051571	positive regulation of histone H3-K4 methylation
0.49	GO:0002168	instar larval development
0.48	GO:0035075	response to ecdysone
0.48	GO:0048813	dendrite morphogenesis
0.46	GO:0006357	regulation of transcription by RNA polymerase II

0.53	GO:0008168	methyltransferase activity
0.49	GO:0046872	metal ion binding
0.45	GO:1990188	euchromatin binding
0.44	GO:0044212	transcription regulatory region DNA binding
0.44	GO:0008013	beta-catenin binding
0.43	GO:0019899	enzyme binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding

0.81	GO:0048188	Set1C/COMPASS complex
0.52	GO:0044666	MLL3/4 complex
0.50	GO:0044665	MLL1/2 complex
0.49	GO:0005703	polytene chromosome puff
0.43	GO:0005719	nuclear euchromatin
0.30	GO:0016020	membrane

0.53

GO:0008168

sp|Q94546|ATU_DROME
Another transcription unit protein
Search

0.83	Another transcription unit proteinlike [Bombus impatiens]

0.81	GO:0006368	transcription elongation from RNA polymerase II promoter
0.74	GO:0016570	histone modification
0.51	GO:0035206	regulation of hemocyte proliferation
0.42	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.39	GO:0050936	xanthophore differentiation
0.39	GO:0021529	spinal cord oligodendrocyte cell differentiation
0.38	GO:0031442	positive regulation of mRNA 3'-end processing
0.38	GO:0030318	melanocyte differentiation
0.38	GO:0014032	neural crest cell development
0.38	GO:0048701	embryonic cranial skeleton morphogenesis

0.42	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding
0.34	GO:0005523	tropomyosin binding
0.33	GO:0016768	spermine synthase activity
0.32	GO:0046982	protein heterodimerization activity
0.31	GO:0003677	DNA binding

0.82	GO:0016593	Cdc73/Paf1 complex
0.37	GO:0001650	fibrillar center
0.36	GO:0005813	centrosome
0.33	GO:0005739	mitochondrion
0.32	GO:0000786	nucleosome
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.5.1.22

GO:0016768

sp|Q94547|RGA_DROME
Regulator of gene activity
Search

RGA

0.37	Regulator of gene activity

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0034249	negative regulation of cellular amide metabolic process
0.52	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.50	GO:0006401	RNA catabolic process
0.50	GO:0032269	negative regulation of cellular protein metabolic process
0.49	GO:0010558	negative regulation of macromolecule biosynthetic process
0.49	GO:0031327	negative regulation of cellular biosynthetic process
0.48	GO:0016071	mRNA metabolic process

0.57	GO:0004535	poly(A)-specific ribonuclease activity
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.55	GO:0030014	CCR4-NOT complex
0.40	GO:0000932	P-body
0.30	GO:0016020	membrane

0.57

EC:3.1.13.4

GO:0004535

tr|Q94883|Q94883_DROME
DNA replication-related element factor, isoform A
Search

DREF

0.71	Zinc finger BED domain-containing protein 1

0.81	GO:2000495	regulation of cell proliferation involved in compound eye morphogenesis
0.80	GO:0045035	sensory organ precursor cell division
0.77	GO:0051900	regulation of mitochondrial depolarization
0.77	GO:0042023	DNA endoreduplication
0.76	GO:0022416	chaeta development
0.74	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly
0.74	GO:0048813	dendrite morphogenesis
0.73	GO:0001745	compound eye morphogenesis
0.73	GO:2000278	regulation of DNA biosynthetic process
0.65	GO:0042981	regulation of apoptotic process

0.77	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.67	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0005509	calcium ion binding
0.33	GO:0046983	protein dimerization activity

0.73	GO:0005700	polytene chromosome
0.66	GO:0005667	transcription factor complex
0.55	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q94887|NRX4_DROME
Neurexin-4
Search

0.71	Contactin-associated protein 1 precursor,putative

0.48	GO:0021682	nerve maturation
0.47	GO:0072553	terminal button organization
0.47	GO:0060857	establishment of glial blood-brain barrier
0.47	GO:0061343	cell adhesion involved in heart morphogenesis
0.47	GO:0097105	presynaptic membrane assembly
0.47	GO:0019991	septate junction assembly
0.47	GO:0008039	synaptic target recognition
0.47	GO:0035151	regulation of tube size, open tracheal system
0.46	GO:0007391	dorsal closure
0.45	GO:0003015	heart process

0.35	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.34	GO:0000287	magnesium ion binding

0.48	GO:0005919	pleated septate junction
0.45	GO:0048786	presynaptic active zone
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.8.7

GO:0008897

sp|Q94890|H15_DROME
T-box protein H15
Search

0.92	LOW QUALITY PROTEIN: T-box protein H15

0.62	GO:0042684	cardioblast cell fate commitment
0.61	GO:0030381	chorion-containing eggshell pattern formation
0.61	GO:0035223	leg disc pattern formation
0.59	GO:0042659	regulation of cell fate specification
0.59	GO:0035050	embryonic heart tube development
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0003015	heart process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.49	GO:0001226	RNA polymerase II transcription corepressor binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0001105	RNA polymerase II transcription coactivator activity
0.38	GO:0001102	RNA polymerase II activating transcription factor binding

0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q94899|CSN2_DROME
COP9 signalosome complex subunit 2
Search

COPS2

0.70	Cop9 signalosome complex subunit

0.78	GO:0000338	protein deneddylation
0.77	GO:0008283	cell proliferation
0.75	GO:0035914	skeletal muscle cell differentiation
0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.62	GO:0048140	male germ-line cyst encapsulation
0.61	GO:0007282	cystoblast division
0.60	GO:0036099	female germ-line stem cell population maintenance
0.59	GO:0007293	germarium-derived egg chamber formation
0.56	GO:0022008	neurogenesis
0.55	GO:0050821	protein stabilization

0.81	GO:0003714	transcription corepressor activity
0.60	GO:0016922	ligand-dependent nuclear receptor binding
0.53	GO:0042803	protein homodimerization activity
0.35	GO:0004871	signal transducer activity

0.81	GO:0008180	COP9 signalosome
0.63	GO:0008231	repressor ecdysone receptor complex
0.48	GO:0005737	cytoplasm
0.36	GO:0005654	nucleoplasm

sp|Q94900|GLUCL_DROME
Glutamate-gated chloride channel
Search

0.76	Glutamate-gated chloride channel subunit type A

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.35	GO:0006821	chloride transport
0.34	GO:0060078	regulation of postsynaptic membrane potential
0.34	GO:0007268	chemical synaptic transmission

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0005254	chloride channel activity
0.35	GO:0099095	ligand-gated anion channel activity

0.56	GO:0005886	plasma membrane
0.34	GO:0034707	chloride channel complex
0.34	GO:0098794	postsynapse
0.34	GO:0030054	cell junction

sp|Q94901|LARK_DROME
RNA-binding protein lark
Search

0.66	RNA binding motif protein 4,lark

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding

0.30

GO:0044425

membrane part

sp|Q94913|REG5_DROME
Rhythmically expressed gene 5 protein
Search

0.84	Rhythmically expressed gene 5

0.68

GO:0048511

rhythmic process

0.30

GO:0044425

membrane part

sp|Q94915|REG2_DROME
Rhythmically expressed gene 2 protein
Search

0.43	rhythmically expressed gene 2 protein-like

0.37	GO:0000338	protein deneddylation
0.32	GO:0008654	phospholipid biosynthetic process

0.51	GO:0016787	hydrolase activity
0.33	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.32	GO:0003677	DNA binding

0.36	GO:0008180	COP9 signalosome
0.30	GO:0044425	membrane part

0.51

GO:0016787

sp|Q94918|VEIN_DROME
Protein vein
Search

0.78	GO:0035310	notum cell fate specification
0.76	GO:0007477	notum development
0.76	GO:0007482	haltere development
0.74	GO:0008355	olfactory learning
0.74	GO:0007494	midgut development
0.74	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.72	GO:0007298	border follicle cell migration
0.71	GO:2000736	regulation of stem cell differentiation
0.71	GO:0007173	epidermal growth factor receptor signaling pathway
0.70	GO:0007422	peripheral nervous system development

0.72	GO:0005154	epidermal growth factor receptor binding
0.69	GO:0008201	heparin binding
0.44	GO:0008083	growth factor activity
0.37	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005509	calcium ion binding

0.43	GO:0005615	extracellular space
0.37	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.33	GO:0097610	cell surface furrow
0.33	GO:0005604	basement membrane
0.33	GO:0032155	cell division site part
0.33	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q94920|VDAC_DROME
Voltage-dependent anion-selective channel
Search

0.44	Mitochondrial voltage-dependent anion channel

0.69	GO:0098656	anion transmembrane transport
0.55	GO:1902017	regulation of cilium assembly
0.49	GO:0030382	sperm mitochondrion organization
0.48	GO:0007291	sperm individualization
0.45	GO:0007602	phototransduction
0.37	GO:0031101	fin regeneration
0.34	GO:0006839	mitochondrial transport
0.34	GO:0007270	neuron-neuron synaptic transmission
0.34	GO:0001662	behavioral fear response
0.34	GO:0007612	learning

0.78	GO:0008308	voltage-gated anion channel activity
0.34	GO:0015288	porin activity

0.78	GO:0005741	mitochondrial outer membrane
0.49	GO:0016006	Nebenkern
0.34	GO:0046930	pore complex
0.34	GO:0008180	COP9 signalosome
0.33	GO:0019866	organelle inner membrane

sp|Q94981|ARI1_DROME
Potential E3 ubiquitin-protein ligase ariadne-1
Search

0.58	Potential E3 ubiquitin-protein ligase ariadne-1

0.72	GO:0016567	protein ubiquitination
0.45	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0007029	endoplasmic reticulum organization
0.44	GO:0048477	oogenesis
0.44	GO:0050769	positive regulation of neurogenesis
0.41	GO:1901800	positive regulation of proteasomal protein catabolic process
0.40	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.32	GO:0055085	transmembrane transport

0.73	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0046872	metal ion binding
0.50	GO:0031624	ubiquitin conjugating enzyme binding
0.49	GO:0016874	ligase activity
0.44	GO:0061659	ubiquitin-like protein ligase activity
0.40	GO:0046983	protein dimerization activity
0.39	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0036402	proteasome-activating ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.42	GO:0097413	Lewy body
0.41	GO:0000151	ubiquitin ligase complex
0.40	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.37	GO:0005737	cytoplasm
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.49	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q95028|LDH_DROME
L-lactate dehydrogenase
Search

0.56	L-lactate dehydrogenase

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0007525	somatic muscle development
0.47	GO:0007520	myoblast fusion

0.81

GO:0004459

L-lactate dehydrogenase activity

0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:1.1.1.27

GO:0004459

sp|Q95029|CATL_DROME
Cathepsin L
Search

0.52	Digestive cysteine protease

0.61	GO:0006508	proteolysis
0.35	GO:0007586	digestion
0.35	GO:0044257	cellular protein catabolic process
0.35	GO:0007275	multicellular organism development
0.34	GO:0030154	cell differentiation
0.34	GO:0006415	translational termination

0.72	GO:0008234	cysteine-type peptidase activity
0.40	GO:0004175	endopeptidase activity
0.34	GO:0003747	translation release factor activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0045169	fusome
0.45	GO:0005764	lysosome
0.35	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.72

GO:0008234

sp|Q95078|CP18A_DROME
Cytochrome P450 18a1
Search

0.38	Cytochrome P450 monooxygenase

0.53	GO:0046344	ecdysteroid catabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0035074	pupation
0.51	GO:0035210	prepupal development
0.49	GO:0007480	imaginal disc-derived leg morphogenesis
0.49	GO:0007304	chorion-containing eggshell formation
0.37	GO:0042572	retinol metabolic process
0.36	GO:0006805	xenobiotic metabolic process
0.35	GO:0019369	arachidonic acid metabolic process
0.35	GO:0002930	trabecular meshwork development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0004252	serine-type endopeptidase activity
0.31	GO:0003676	nucleic acid binding

0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031090	organelle membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q95083|PSA5_DROME
Proteasome subunit alpha type-5
Search

0.49	Proteasome endopeptidase complex

0.77	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0008063	Toll signaling pathway
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0007623	circadian rhythm
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0070062	extracellular exosome
0.34	GO:0044446	intracellular organelle part
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|Q95NH6|ATTC_DROME
Attacin-C
Search

0.97	Antibacterial peptide attacin A

0.78	GO:0042742	defense response to bacterium
0.43	GO:0019730	antimicrobial humoral response
0.42	GO:0045087	innate immune response
0.37	GO:0055093	response to hyperoxia

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|Q95NU8|Q95NU8_DROME
GH16255p
Search

0.86	GO:1900074	negative regulation of neuromuscular synaptic transmission
0.86	GO:0042694	muscle cell fate specification
0.86	GO:0007522	visceral muscle development
0.86	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.85	GO:0051124	synaptic growth at neuromuscular junction
0.85	GO:0042051	compound eye photoreceptor development
0.84	GO:0007435	salivary gland morphogenesis
0.79	GO:0007411	axon guidance
0.78	GO:0043410	positive regulation of MAPK cascade
0.50	GO:0007509	mesoderm migration involved in gastrulation

0.86	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.36	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.34	GO:0008233	peptidase activity

0.87	GO:0061177	type Is terminal bouton
0.86	GO:0061176	type Ib terminal bouton
0.80	GO:0008021	synaptic vesicle
0.72	GO:0005615	extracellular space
0.35	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0008233

tr|Q95PE4|Q95PE4_DROME
GEO07784p1
Search

0.72	M-phase phosphoprotein 6

0.81

GO:0000460

maturation of 5.8S rRNA

0.84

GO:0000176

nuclear exosome (RNase complex)

tr|Q95R29|Q95R29_DROME
HL03650p
Search

0.86	GO:0042754	negative regulation of circadian rhythm
0.72	GO:0045892	negative regulation of transcription, DNA-templated

tr|Q95R34|Q95R34_DROME
CG3191, isoform A
Search

0.54	Retinaldehyde-binding protein 1

0.30

GO:0044425

membrane part

tr|Q95R35|Q95R35_DROME
AT09752p
Search

0.51	cytosol aminopeptidase

0.61	GO:0006508	proteolysis
0.43	GO:0007498	mesoderm development
0.34	GO:0032504	multicellular organism reproduction
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0006468	protein phosphorylation

0.74	GO:0008235	metalloexopeptidase activity
0.73	GO:0030145	manganese ion binding
0.71	GO:0004177	aminopeptidase activity
0.36	GO:0003995	acyl-CoA dehydrogenase activity
0.35	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0016874	ligase activity

0.49	GO:0005737	cytoplasm
0.42	GO:0030496	midbody
0.39	GO:0005654	nucleoplasm
0.35	GO:0005615	extracellular space
0.33	GO:0005925	focal adhesion
0.33	GO:1903561	extracellular vesicle
0.33	GO:0031984	organelle subcompartment
0.32	GO:0012505	endomembrane system

0.71

GO:0004177

sp|Q95R48|OCTL_DROME
Organic cation transporter-like protein
Search

0.40	Organic cation transporter

0.55	GO:0055085	transmembrane transport
0.49	GO:0007390	germ-band shortening
0.48	GO:0040018	positive regulation of multicellular organism growth
0.47	GO:0030307	positive regulation of cell growth
0.39	GO:0015711	organic anion transport
0.38	GO:0015695	organic cation transport
0.36	GO:0015696	ammonium transport
0.36	GO:0015837	amine transport
0.36	GO:0030317	flagellated sperm motility
0.36	GO:0007338	single fertilization

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0016603	glutaminyl-peptide cyclotransferase activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0030165	PDZ domain binding
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding
0.32	GO:0003677	DNA binding

0.38	GO:0005887	integral component of plasma membrane
0.33	GO:0009705	plant-type vacuole membrane
0.32	GO:0016324	apical plasma membrane
0.32	GO:0005739	mitochondrion

0.33

EC:2.3.2.5

GO:0016603

tr|Q95R73|Q95R73_DROME
SD03412p
Search

0.40	N-acetylglucosamine-6-sulfatase

0.63	GO:0030203	glycosaminoglycan metabolic process
0.42	GO:0018958	phenol-containing compound metabolic process
0.34	GO:0032781	positive regulation of ATPase activity
0.34	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.34	GO:0051259	protein oligomerization
0.33	GO:0006672	ceramide metabolic process
0.31	GO:0055085	transmembrane transport

0.82	GO:0008449	N-acetylglucosamine-6-sulfatase activity
0.44	GO:0004065	arylsulfatase activity
0.38	GO:0046872	metal ion binding
0.34	GO:0001671	ATPase activator activity
0.34	GO:0051087	chaperone binding
0.33	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.31	GO:0003676	nucleic acid binding

0.52	GO:0005764	lysosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.82

EC:3.1.6.14

GO:0008449

tr|Q95R98|Q95R98_DROME
Protein phosphatase methylesterase 1
Search

0.73	Phosphatase methylesterase (Fragment)

0.84	GO:0006482	protein demethylation
0.40	GO:0043666	regulation of phosphoprotein phosphatase activity
0.33	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0022900	electron transport chain

0.79	GO:0051723	protein methylesterase activity
0.40	GO:0019888	protein phosphatase regulator activity
0.35	GO:0051721	protein phosphatase 2A binding
0.34	GO:0045296	cadherin binding
0.33	GO:0016740	transferase activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0046872	metal ion binding

0.33

GO:0016740

tr|Q95RA0|Q95RA0_DROME
GEO09367p1
Search

0.10	NADH-quinone oxidoreductase subunit D

0.30

GO:0008152

metabolic process

0.30

GO:0003824

catalytic activity

0.30

GO:0044425

membrane part

sp|Q95RA8|MOB1_DROME
MOB kinase activator-like 1
Search

0.77	Mps one binder kinase activator

0.53	GO:0016310	phosphorylation
0.53	GO:0031952	regulation of protein autophosphorylation
0.52	GO:0035329	hippo signaling
0.49	GO:0030707	ovarian follicle cell development
0.49	GO:0042327	positive regulation of phosphorylation
0.48	GO:0008283	cell proliferation
0.47	GO:0006915	apoptotic process
0.45	GO:0007059	chromosome segregation
0.45	GO:0007275	multicellular organism development
0.35	GO:0048646	anatomical structure formation involved in morphogenesis

0.56	GO:0016301	kinase activity
0.55	GO:0019900	kinase binding
0.51	GO:0019209	kinase activator activity
0.35	GO:0046872	metal ion binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005829	cytosol
0.47	GO:0005730	nucleolus
0.47	GO:0005813	centrosome
0.39	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016773

sp|Q95RA9|GILT1_DROME
GILT-like protein 1
Search

0.66	Gamma-interferon-inducible lysosomal thiol reductase

0.71	GO:1900426	positive regulation of defense response to bacterium
0.39	GO:0002376	immune system process
0.35	GO:0055114	oxidation-reduction process

0.39

GO:0015036

disulfide oxidoreductase activity

0.48	GO:0005886	plasma membrane
0.38	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q95RB1|Q95RB1_DROME
LD46870p
Search

RBM22

0.81	RNA binding motif protein 22

0.52	GO:0033120	positive regulation of RNA splicing
0.50	GO:0046827	positive regulation of protein export from nucleus
0.50	GO:0045292	mRNA cis splicing, via spliceosome
0.50	GO:0000060	protein import into nucleus, translocation
0.49	GO:0042307	positive regulation of protein import into nucleus
0.48	GO:0035690	cellular response to drug
0.46	GO:0000387	spliceosomal snRNP assembly
0.40	GO:0043009	chordate embryonic development
0.35	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0090316	positive regulation of intracellular protein transport

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.49	GO:0048306	calcium-dependent protein binding
0.34	GO:0005487	structural constituent of nuclear pore

0.54	GO:0071007	U2-type catalytic step 2 spliceosome
0.48	GO:0071006	U2-type catalytic step 1 spliceosome
0.47	GO:0000974	Prp19 complex
0.37	GO:0005737	cytoplasm
0.35	GO:0071011	precatalytic spliceosome
0.33	GO:0005654	nucleoplasm

tr|Q95RB2|Q95RB2_DROME
Cuticular protein 49Ae
Search

0.65	Endocuticle structural glycoprotein SgAbd-1

0.39	GO:0040003	chitin-based cuticle development
0.34	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.32	GO:0007165	signal transduction

0.79	GO:0042302	structural constituent of cuticle
0.34	GO:0008527	taste receptor activity

0.37	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|Q95RC0|NAA30_DROME
N-alpha-acetyltransferase 30
Search

NAA30

0.77	N-terminal acetyltransferase C complex catalytic subunit Mak3

0.52	GO:0006473	protein acetylation
0.51	GO:0018206	peptidyl-methionine modification
0.49	GO:0031365	N-terminal protein amino acid modification
0.47	GO:0051604	protein maturation
0.42	GO:0016570	histone modification
0.42	GO:0018205	peptidyl-lysine modification

0.68	GO:0008080	N-acetyltransferase activity
0.33	GO:0005515	protein binding

0.52	GO:0031417	NatC complex
0.48	GO:0005844	polysome
0.43	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.68

GO:0008080

tr|Q95RC5|Q95RC5_DROME
CG5745
Search

0.69	Ypt/rab specific gtpase activating protein gyp1

0.75	GO:0031338	regulation of vesicle fusion
0.74	GO:0090630	activation of GTPase activity
0.62	GO:0006886	intracellular protein transport
0.50	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:1902017	regulation of cilium assembly

0.71	GO:0017137	Rab GTPase binding
0.67	GO:0005096	GTPase activator activity
0.62	GO:0071889	14-3-3 protein binding
0.51	GO:0042803	protein homodimerization activity
0.35	GO:0003723	RNA binding

0.60	GO:0012505	endomembrane system
0.50	GO:0005681	spliceosomal complex

tr|Q95RC8|Q95RC8_DROME
LD44171p
Search

0.87	GO:0090052	regulation of chromatin silencing at centromere
0.75	GO:0006366	transcription by RNA polymerase II
0.75	GO:0006302	double-strand break repair
0.75	GO:0045944	positive regulation of transcription by RNA polymerase II

0.85	GO:0001105	RNA polymerase II transcription coactivator activity
0.43	GO:0042802	identical protein binding
0.34	GO:0003677	DNA binding

0.85	GO:0005719	nuclear euchromatin
0.77	GO:0000775	chromosome, centromeric region

tr|Q95RE4|Q95RE4_DROME
LD37574p
Search

0.83	Ypsilon schachtel

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0009967	positive regulation of signal transduction
0.33	GO:0007165	signal transduction
0.32	GO:0006351	transcription, DNA-templated
0.30	GO:0007276	gamete generation
0.30	GO:0008380	RNA splicing
0.30	GO:0022412	cellular process involved in reproduction in multicellular organism

0.55	GO:0003677	DNA binding
0.35	GO:0005096	GTPase activator activity
0.35	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003723	RNA binding

0.33	GO:0005634	nucleus
0.30	GO:0044422	organelle part
0.30	GO:0016020	membrane
0.30	GO:0032991	macromolecular complex

tr|Q95RF3|Q95RF3_DROME
LD34806p
Search

0.10	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

0.80	GO:0006487	protein N-linked glycosylation
0.37	GO:0006488	dolichol-linked oligosaccharide biosynthetic process

0.85	GO:0003830	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
0.37	GO:0003975	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
0.36	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity

0.30

GO:0031224

intrinsic component of membrane

0.85

EC:2.4.1.144

GO:0003830

tr|Q95RF6|Q95RF6_DROME
LD34461p
Search

TOMM20

0.77	Mitochondrial import receptor subunit

0.71	GO:0006605	protein targeting
0.48	GO:0072655	establishment of protein localization to mitochondrion
0.48	GO:0016031	tRNA import into mitochondrion
0.47	GO:0070096	mitochondrial outer membrane translocase complex assembly
0.45	GO:0071806	protein transmembrane transport
0.43	GO:0017038	protein import
0.41	GO:1905242	response to 3,3',5-triiodo-L-thyronine
0.40	GO:0014850	response to muscle activity
0.34	GO:0016236	macroautophagy
0.34	GO:0016579	protein deubiquitination

0.48	GO:0030943	mitochondrion targeting sequence binding
0.47	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.43	GO:0051082	unfolded protein binding
0.33	GO:0005198	structural molecule activity
0.32	GO:0003723	RNA binding

0.84	GO:0005742	mitochondrial outer membrane translocase complex
0.47	GO:0044233	ER-mitochondrion membrane contact site
0.45	GO:0031307	integral component of mitochondrial outer membrane
0.36	GO:0031012	extracellular matrix
0.33	GO:0005840	ribosome
0.32	GO:0005581	collagen trimer

tr|Q95RF7|Q95RF7_DROME
GEO09362p1
Search

tr|Q95RG8|Q95RG8_DROME
G protein-coupled receptor kinase interacting ArfGAP
Search

GIT1

0.81	G protein-coupled receptor kinase interacting ArfGAP

0.76	GO:0043547	positive regulation of GTPase activity
0.56	GO:1905383	protein localization to presynapse
0.54	GO:0035332	positive regulation of hippo signaling
0.53	GO:0016319	mushroom body development
0.53	GO:0007525	somatic muscle development
0.52	GO:0036465	synaptic vesicle recycling
0.51	GO:0046620	regulation of organ growth
0.44	GO:0048013	ephrin receptor signaling pathway
0.43	GO:0032465	regulation of cytokinesis
0.39	GO:0001525	angiogenesis

0.76	GO:0005096	GTPase activator activity
0.53	GO:0046872	metal ion binding
0.50	GO:0032947	protein complex scaffold activity
0.42	GO:0032403	protein complex binding
0.35	GO:0016301	kinase activity
0.33	GO:0031267	small GTPase binding
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0016787	hydrolase activity

0.54	GO:0048788	cytoskeleton of presynaptic active zone
0.50	GO:0031252	cell leading edge
0.44	GO:0005925	focal adhesion
0.41	GO:0005829	cytosol
0.34	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0098590	plasma membrane region
0.33	GO:0044463	cell projection part
0.30	GO:0016021	integral component of membrane

0.32

GO:0016787

tr|Q95RH3|Q95RH3_DROME
LD29716p
Search

0.75	GO:0006302	double-strand break repair
0.35	GO:0006468	protein phosphorylation
0.34	GO:0007165	signal transduction

0.35	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0004871	signal transducer activity
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q95RI2|Q95RI2_DROME
LD28549p
Search

0.11	hsp70 nucleotide exchange factor fes1

0.67	GO:0050790	regulation of catalytic activity
0.64	GO:0044092	negative regulation of molecular function
0.54	GO:0071629	cytoplasm protein quality control by the ubiquitin-proteasome system
0.48	GO:0006417	regulation of translation

0.69	GO:0030234	enzyme regulator activity
0.41	GO:0030554	adenyl nucleotide binding

0.46

GO:0005829

cytosol

sp|Q95RI5|FAXC_DROME
Failed axon connections
Search

0.36	Glutathione S-transferase

0.63

GO:0007409

axonogenesis

0.46	GO:0016740	transferase activity
0.37	GO:0005515	protein binding

0.36	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm

0.46

GO:0016740

tr|Q95RI7|Q95RI7_DROME
LD28068p
Search

0.74	Putative survival motor neuron protein aedes aegypti splicing factor

0.69	GO:0006397	mRNA processing
0.38	GO:0008380	RNA splicing
0.38	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0006915	apoptotic process
0.33	GO:0032988	ribonucleoprotein complex disassembly

0.58	GO:0003723	RNA binding
0.32	GO:0005515	protein binding
0.32	GO:0016831	carboxy-lyase activity
0.31	GO:0016787	hydrolase activity

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0044446	intracellular organelle part
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:4.1.1

GO:0016831

sp|Q95RJ9|EBI_DROME
F-box-like/WD repeat-containing protein ebi
Search

EBI

0.88	F-box-like/WD repeat-containing protein ebi

0.84	GO:0045572	positive regulation of imaginal disc growth
0.81	GO:0031065	positive regulation of histone deacetylation
0.81	GO:0070050	neuron cellular homeostasis
0.81	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.80	GO:0022416	chaeta development
0.80	GO:0046329	negative regulation of JNK cascade
0.78	GO:0045747	positive regulation of Notch signaling pathway
0.78	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.77	GO:0042461	photoreceptor cell development
0.77	GO:0043524	negative regulation of neuron apoptotic process

0.79	GO:0001106	RNA polymerase II transcription corepressor activity
0.78	GO:0070491	repressing transcription factor binding
0.70	GO:0003682	chromatin binding
0.40	GO:0004402	histone acetyltransferase activity

0.77	GO:0005700	polytene chromosome
0.74	GO:0017053	transcriptional repressor complex
0.60	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.46	GO:1902494	catalytic complex
0.44	GO:0044446	intracellular organelle part
0.38	GO:0019013	viral nucleocapsid
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0004402

tr|Q95RM0|Q95RM0_DROME
LD20362p
Search

0.42

GO:0006468

protein phosphorylation

0.42	GO:0004672	protein kinase activity
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003676	nucleic acid binding

sp|Q95RN0|U528_DROME
UPF0528 protein CG10038
Search

0.44	GO:0016192	vesicle-mediated transport
0.39	GO:0006885	regulation of pH
0.38	GO:0035725	sodium ion transmembrane transport

0.50	GO:0016788	hydrolase activity, acting on ester bonds
0.40	GO:0035091	phosphatidylinositol binding
0.39	GO:0015385	sodium:proton antiporter activity

0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.50

GO:0016788

tr|Q95RP1|Q95RP1_DROME
LD18295p
Search

0.11	Riboflavin biosynthesis protein RibD

0.76

GO:0006030

chitin metabolic process

0.75

GO:0008061

chitin binding

0.65	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q95RP8|Q95RP8_DROME
Hexosyltransferase
Search

0.55	Hexosyltransferase

0.74

GO:0006486

protein glycosylation

0.81

GO:0008378

galactosyltransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008378

tr|Q95RQ1|Q95RQ1_DROME
LD16414p
Search

0.83	Epidermal growth factor-like protein 8

0.69	GO:0044719	regulation of imaginal disc-derived wing size
0.69	GO:0008039	synaptic target recognition
0.68	GO:0016203	muscle attachment
0.45	GO:0007219	Notch signaling pathway
0.41	GO:0050793	regulation of developmental process
0.37	GO:0097111	endoplasmic reticulum-Golgi intermediate compartment organization
0.36	GO:0097352	autophagosome maturation
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:0060854	branching involved in lymph vessel morphogenesis
0.33	GO:0060855	venous endothelial cell migration involved in lymph vessel development

0.68	GO:0005509	calcium ion binding
0.36	GO:0000149	SNARE binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.32	GO:0005201	extracellular matrix structural constituent
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0005507	copper ion binding
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.69	GO:0005927	muscle tendon junction
0.34	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0044420	extracellular matrix component
0.32	GO:0005737	cytoplasm
0.32	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.33

GO:0004222

tr|Q95RQ4|Q95RQ4_DROME
LD16074p
Search

ERI2

0.42	3' histone mRNA exonuclease 1

0.42	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0006259	DNA metabolic process
0.39	GO:0071044	histone mRNA catabolic process
0.32	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.32	GO:0008299	isoprenoid biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.46	GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity
0.46	GO:0008270	zinc ion binding
0.45	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity
0.43	GO:0000175	3'-5'-exoribonuclease activity
0.33	GO:0004654	polyribonucleotide nucleotidyltransferase activity
0.32	GO:0005509	calcium ion binding

0.30

GO:0016020

membrane

0.43

EC:3.1.13

GO:0000175

tr|Q95RQ7|Q95RQ7_DROME
LD15658p
Search

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.79	GO:0008097	5S rRNA binding
0.64	GO:0003735	structural constituent of ribosome

0.61

GO:0005840

ribosome

tr|Q95RQ8|Q95RQ8_DROME
LD15650p
Search

0.62	gastrula zinc finger protein 5-1

0.64	GO:0042023	DNA endoreduplication
0.60	GO:0060968	regulation of gene silencing
0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0006457	protein folding
0.33	GO:0035914	skeletal muscle cell differentiation
0.32	GO:0006366	transcription by RNA polymerase II
0.31	GO:0007165	signal transduction

0.65	GO:0043035	chromatin insulator sequence binding
0.56	GO:0008270	zinc ion binding
0.50	GO:0043565	sequence-specific DNA binding
0.39	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0044212	transcription regulatory region DNA binding

0.62	GO:0005700	polytene chromosome
0.55	GO:0005634	nucleus

sp|Q95RR8|PAN3_DROME
PAB-dependent poly(A)-specific ribonuclease subunit PAN3
Search

PAN3

0.75	PAB-dependent poly(A)-specific ribonuclease subunit 3 (Fragment)

0.84	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.83	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.69	GO:0006397	mRNA processing
0.48	GO:0006468	protein phosphorylation
0.39	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.37	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic

0.58	GO:0003723	RNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0004672	protein kinase activity
0.39	GO:0004535	poly(A)-specific ribonuclease activity
0.36	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.84	GO:0031251	PAN complex
0.78	GO:0000932	P-body
0.30	GO:0016020	membrane

0.39

EC:3.1.13.4

GO:0004535

tr|Q95RS6|Q95RS6_DROME
IP12536p
Search

0.38	Prophenoloxidase activating factor

0.61	GO:0006508	proteolysis
0.32	GO:0055114	oxidation-reduction process

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004503	monophenol monooxygenase activity

0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|Q95RU0|CUE_DROME
Protein cueball
Search

0.10	Low-density lipoprotein receptor repeat class B

0.68	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.66	GO:0070328	triglyceride homeostasis
0.61	GO:0048477	oogenesis
0.60	GO:0007283	spermatogenesis
0.39	GO:0030509	BMP signaling pathway
0.38	GO:0060828	regulation of canonical Wnt signaling pathway
0.37	GO:0007275	multicellular organism development
0.36	GO:1990709	presynaptic active zone organization
0.35	GO:0007219	Notch signaling pathway
0.32	GO:0006030	chitin metabolic process

0.53	GO:0005509	calcium ion binding
0.32	GO:0008061	chitin binding
0.30	GO:0003824	catalytic activity

0.45	GO:0005886	plasma membrane
0.35	GO:0043679	axon terminus
0.32	GO:0005739	mitochondrion
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q95RV2|CAV_DROME
Telomere-binding protein cav
Search

CAV

0.97	Telomere-binding protein cav

0.85

GO:0016233

telomere capping

0.82	GO:0042162	telomeric DNA binding
0.48	GO:0005515	protein binding

0.85	GO:0000782	telomere cap complex
0.82	GO:0000784	nuclear chromosome, telomeric region
0.77	GO:0000775	chromosome, centromeric region

tr|Q95RV3|Q95RV3_DROME
LD09786p
Search

LHR

0.97	Lethal hybrid rescue protein

0.60	GO:0010529	negative regulation of transposition
0.59	GO:0070868	heterochromatin organization involved in chromatin silencing
0.55	GO:0000070	mitotic sister chromatid segregation
0.55	GO:0000723	telomere maintenance

0.55	GO:0003677	DNA binding
0.35	GO:0005515	protein binding

0.61	GO:0035012	polytene chromosome, telomeric region
0.61	GO:0005634	nucleus
0.59	GO:0010369	chromocenter
0.56	GO:0000792	heterochromatin
0.54	GO:0000775	chromosome, centromeric region

tr|Q95RV5|Q95RV5_DROME
Ribulose-phosphate 3-epimerase
Search

0.42	Ribulose-phosphate 3-epimerase

0.71	GO:0006098	pentose-phosphate shunt
0.60	GO:0005975	carbohydrate metabolic process
0.40	GO:0060271	cilium assembly
0.38	GO:0044282	small molecule catabolic process
0.37	GO:1901575	organic substance catabolic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.78	GO:0004750	ribulose-phosphate 3-epimerase activity
0.53	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.38

GO:0005829

cytosol

0.78	EC:5.1.3.1	GO:0004750
0.78	KEGG:R01529	GO:0004750

sp|Q95RW8|OPTIX_DROME
Protein Optix
Search

0.70	Homeobox protein SIX3

0.62	GO:0001654	eye development
0.58	GO:0007399	nervous system development
0.55	GO:0090596	sensory organ morphogenesis
0.55	GO:0060322	head development
0.52	GO:0048468	cell development
0.51	GO:0016358	dendrite development
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0097402	neuroblast migration
0.49	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.49	GO:1990086	lens fiber cell apoptotic process

0.55	GO:0003677	DNA binding
0.52	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.48	GO:0001222	transcription corepressor binding
0.46	GO:0042826	histone deacetylase binding
0.45	GO:0003713	transcription coactivator activity
0.43	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0005102	receptor binding

0.61

GO:0005634

nucleus

tr|Q95RX5|Q95RX5_DROME
LD03515p
Search

KCMF1

0.66	Zinc finger, ZZ type

0.37	GO:0006486	protein glycosylation
0.34	GO:0043312	neutrophil degranulation
0.33	GO:0016567	protein ubiquitination

0.62	GO:0008270	zinc ion binding
0.48	GO:0016874	ligase activity
0.43	GO:0003676	nucleic acid binding
0.38	GO:0008378	galactosyltransferase activity
0.34	GO:0061630	ubiquitin protein ligase activity

0.41	GO:0005829	cytosol
0.35	GO:1904813	ficolin-1-rich granule lumen
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.48

GO:0016874

tr|Q95RY2|Q95RY2_DROME
CG7945, isoform A
Search

BAG2

0.82	BAG family molecular chaperone regulator 2

0.68	GO:0050790	regulation of catalytic activity
0.36	GO:0006457	protein folding
0.32	GO:0016310	phosphorylation

0.79	GO:0000774	adenyl-nucleotide exchange factor activity
0.77	GO:0051087	chaperone binding
0.32	GO:0016301	kinase activity

0.30

GO:0044425

membrane part

tr|Q95SH0|Q95SH0_DROME
GH26463p
Search

0.11	PAS domain-containing serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.46	GO:0070092	regulation of glucagon secretion
0.45	GO:0045719	negative regulation of glycogen biosynthetic process
0.45	GO:2000505	regulation of energy homeostasis
0.45	GO:0043576	regulation of respiratory gaseous exchange
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:0043066	negative regulation of apoptotic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0035091	phosphatidylinositol binding
0.33	GO:0003690	double-stranded DNA binding
0.33	GO:0004930	G-protein coupled receptor activity

0.40	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q95SH2|Q95SH2_DROME
Charged multivesicular body protein 1, isoform A
Search

0.79	Charged multivesicular body protein 1, isoform A

0.78	GO:0007034	vacuolar transport
0.46	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.37	GO:1901673	regulation of mitotic spindle assembly
0.37	GO:0045184	establishment of protein localization
0.37	GO:0000920	cell separation after cytokinesis
0.37	GO:0007080	mitotic metaphase plate congression
0.37	GO:0010824	regulation of centrosome duplication
0.37	GO:0042886	amide transport
0.36	GO:0006997	nucleus organization
0.36	GO:0039702	viral budding via host ESCRT complex

0.36	GO:0019904	protein domain specific binding
0.35	GO:0042802	identical protein binding

0.47	GO:0005770	late endosome
0.44	GO:0045177	apical part of cell
0.40	GO:0010008	endosome membrane
0.37	GO:0036452	ESCRT complex
0.37	GO:0005829	cytosol
0.36	GO:0030117	membrane coat
0.35	GO:0030496	midbody
0.35	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

tr|Q95SH7|Q95SH7_DROME
GH26007p
Search

0.12	osteopetrosis-associated transmembrane protein 1

0.45	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|Q95SI7|Q95SI7_DROME
CG6028
Search

0.39	fumarylacetoacetate hydrolase domain-containing protein 2

0.34	GO:0055114	oxidation-reduction process
0.32	GO:0005975	carbohydrate metabolic process

0.44	GO:0016853	isomerase activity
0.40	GO:0016787	hydrolase activity
0.38	GO:0016829	lyase activity
0.37	GO:0051213	dioxygenase activity
0.34	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016853

sp|Q95SK3|CK5P3_DROME
CDK5RAP3-like protein
Search

0.63	CDK5 regulatory subunit-associated protein 3

0.74	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.73	GO:0007346	regulation of mitotic cell cycle
0.73	GO:1901798	positive regulation of signal transduction by p53 class mediator
0.73	GO:0071569	protein ufmylation
0.72	GO:0071900	regulation of protein serine/threonine kinase activity
0.71	GO:0030262	apoptotic nuclear changes
0.70	GO:0031572	G2 DNA damage checkpoint
0.70	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.70	GO:1903363	negative regulation of cellular protein catabolic process
0.68	GO:1902750	negative regulation of cell cycle G2/M phase transition

0.74	GO:0097371	MDM2/MDM4 family protein binding
0.71	GO:0051019	mitogen-activated protein kinase binding
0.71	GO:0051059	NF-kappaB binding
0.67	GO:0030332	cyclin binding
0.65	GO:0044389	ubiquitin-like protein ligase binding
0.37	GO:0032403	protein complex binding

0.64	GO:0005813	centrosome
0.61	GO:0005874	microtubule
0.60	GO:0005730	nucleolus
0.56	GO:0005829	cytosol
0.55	GO:0012505	endomembrane system
0.51	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|Q95SM8|Q95SM8_DROME
GH13859p
Search

0.64	fibrinogen C domain-containing protein 1

0.75	GO:0001525	angiogenesis
0.71	GO:0043066	negative regulation of apoptotic process
0.53	GO:0051005	negative regulation of lipoprotein lipase activity
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.51	GO:0070328	triglyceride homeostasis
0.50	GO:1902262	apoptotic process involved in blood vessel morphogenesis
0.45	GO:0009617	response to bacterium
0.40	GO:0030154	cell differentiation
0.40	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0048014	Tie signaling pathway

0.46	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.42	GO:0001664	G-protein coupled receptor binding
0.41	GO:0008061	chitin binding
0.37	GO:0030971	receptor tyrosine kinase binding

0.67	GO:0005615	extracellular space
0.53	GO:0030141	secretory granule
0.39	GO:1903561	extracellular vesicle
0.37	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016020	membrane

tr|Q95SN8|Q95SN8_DROME
GH12395p
Search

0.13	serine protease easter

0.61

GO:0006508

proteolysis

0.69

GO:0004252

serine-type endopeptidase activity

0.69

GO:0004252

sp|Q95SP2|HRD1_DROME
E3 ubiquitin-protein ligase HRD1
Search

0.65	Synovial apoptosis inhibitor 1, synoviolin

0.82	GO:0030433	ubiquitin-dependent ERAD pathway
0.73	GO:0016567	protein ubiquitination
0.53	GO:0030968	endoplasmic reticulum unfolded protein response
0.51	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.50	GO:0018279	protein N-linked glycosylation via asparagine
0.50	GO:0036490	regulation of translation in response to endoplasmic reticulum stress
0.50	GO:0030970	retrograde protein transport, ER to cytosol
0.50	GO:0036335	intestinal stem cell homeostasis
0.48	GO:0050821	protein stabilization
0.37	GO:0001701	in utero embryonic development

0.76	GO:0061630	ubiquitin protein ligase activity
0.54	GO:1990381	ubiquitin-specific protease binding
0.50	GO:0051117	ATPase binding
0.48	GO:0016874	ligase activity
0.48	GO:0002039	p53 binding
0.47	GO:0051087	chaperone binding
0.47	GO:0051082	unfolded protein binding
0.35	GO:0046872	metal ion binding
0.34	GO:0033613	activating transcription factor binding

0.85	GO:0000836	Hrd1p ubiquitin ligase complex
0.53	GO:0036513	Derlin-1 retrotranslocation complex
0.51	GO:0005790	smooth endoplasmic reticulum
0.48	GO:0044322	endoplasmic reticulum quality control compartment
0.44	GO:0005654	nucleoplasm
0.34	GO:0030176	integral component of endoplasmic reticulum membrane

0.48

GO:0016874

tr|Q95SR0|Q95SR0_DROME
GH07390p
Search

0.51	Aminopeptidase N

0.61	GO:0006508	proteolysis
0.40	GO:0043171	peptide catabolic process
0.37	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.35	GO:0008217	regulation of blood pressure
0.34	GO:0007267	cell-cell signaling
0.33	GO:0060177	regulation of angiotensin metabolic process
0.33	GO:0050886	endocrine process
0.33	GO:0042445	hormone metabolic process
0.33	GO:0007165	signal transduction
0.32	GO:0051604	protein maturation

0.70	GO:0004177	aminopeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding
0.40	GO:0042277	peptide binding

0.35	GO:0005783	endoplasmic reticulum
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.70

GO:0004177

sp|Q95SS8|TMM70_DROME
Transmembrane protein 70 homolog, mitochondrial
Search

0.56	Transmembrane protein 70, mitochondrial

0.42	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly
0.37	GO:0032447	protein urmylation
0.36	GO:0034227	tRNA thio-modification
0.36	GO:0002098	tRNA wobble uridine modification

0.40	GO:0032592	integral component of mitochondrial membrane
0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol

sp|Q95ST2|WLS_DROME
Protein wntless
Search

0.39	G protein-coupled receptor

0.77	GO:0016055	Wnt signaling pathway
0.60	GO:0061355	Wnt protein secretion
0.60	GO:0061357	positive regulation of Wnt protein secretion
0.59	GO:0035017	cuticle pattern formation
0.59	GO:0007367	segment polarity determination
0.58	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.58	GO:0007480	imaginal disc-derived leg morphogenesis
0.57	GO:0043001	Golgi to plasma membrane protein transport
0.56	GO:0001745	compound eye morphogenesis
0.56	GO:0030177	positive regulation of Wnt signaling pathway

0.85	GO:0017147	Wnt-protein binding
0.38	GO:0015078	hydrogen ion transmembrane transporter activity

0.61	GO:0031302	intrinsic component of endosome membrane
0.59	GO:0030285	integral component of synaptic vesicle membrane
0.57	GO:0005771	multivesicular body
0.57	GO:0042734	presynaptic membrane
0.56	GO:0031594	neuromuscular junction
0.55	GO:0031228	intrinsic component of Golgi membrane
0.54	GO:0070062	extracellular exosome
0.54	GO:0005769	early endosome
0.54	GO:0045211	postsynaptic membrane
0.53	GO:0031227	intrinsic component of endoplasmic reticulum membrane

sp|Q95SX8|NAA60_DROME
N-alpha-acetyltransferase 60
Search

0.64	N-alpha-acetyltransferase 60

0.59	GO:0017196	N-terminal peptidyl-methionine acetylation
0.53	GO:0016573	histone acetylation
0.48	GO:0007059	chromosome segregation
0.47	GO:0006334	nucleosome assembly
0.45	GO:0008283	cell proliferation
0.35	GO:0016055	Wnt signaling pathway
0.34	GO:0016567	protein ubiquitination

0.67	GO:0008080	N-acetyltransferase activity
0.43	GO:0042803	protein homodimerization activity
0.36	GO:0072572	poly-ADP-D-ribose binding
0.35	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.67

GO:0008080

tr|Q95T08|Q95T08_DROME
CG9636, isoform C
Search

0.77	CUE domain-containing protein 2

0.87

GO:0010936

negative regulation of macrophage cytokine production

0.70

GO:0005654

nucleoplasm

sp|Q95T10|XYLK_DROME
Glycosaminoglycan xylosylkinase homolog
Search

0.48	Glycosaminoglycan xylosylkinase

0.49	GO:0016310	phosphorylation
0.42	GO:1903955	positive regulation of protein targeting to mitochondrion
0.41	GO:0048701	embryonic cranial skeleton morphogenesis
0.41	GO:0030166	proteoglycan biosynthetic process
0.40	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.33	GO:0055085	transmembrane transport

0.50	GO:0016301	kinase activity
0.43	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.33	GO:0022857	transmembrane transporter activity

0.48	GO:0005794	Golgi apparatus
0.45	GO:0005783	endoplasmic reticulum
0.39	GO:0005615	extracellular space
0.39	GO:0005654	nucleoplasm
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.43

GO:0016773

sp|Q95T12|FLOWR_DROME
Calcium channel flower
Search

FLOWER

0.65	Calcium channel flower

0.60	GO:0099533	positive regulation of presynaptic cytosolic calcium concentration
0.57	GO:0035212	cell competition in a multicellular organism
0.56	GO:0043525	positive regulation of neuron apoptotic process
0.55	GO:0048488	synaptic vesicle endocytosis
0.52	GO:0046530	photoreceptor cell differentiation
0.51	GO:0070588	calcium ion transmembrane transport
0.35	GO:0006914	autophagy
0.34	GO:0015031	protein transport

0.52	GO:0005262	calcium channel activity
0.49	GO:0042802	identical protein binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0044214	spanning component of plasma membrane
0.57	GO:0030285	integral component of synaptic vesicle membrane
0.48	GO:0030054	cell junction

sp|Q95T19|SLIMP_DROME
Serine--tRNA synthetase-like protein Slimp
Search

0.75	Serine--tRNA ligase, mitochondrial

0.79	GO:0006434	seryl-tRNA aminoacylation
0.70	GO:0070584	mitochondrion morphogenesis
0.52	GO:0045333	cellular respiration

0.79	GO:0004828	serine-tRNA ligase activity
0.57	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding

0.51	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus

0.79

EC:6.1.1.11

GO:0004828

tr|Q95T35|Q95T35_DROME
GH27234p
Search

0.67	Oxoglutarate dehydrogenase

0.71	GO:0006099	tricarboxylic acid cycle
0.32	GO:0016579	protein deubiquitination

0.80	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity
0.73	GO:0030976	thiamine pyrophosphate binding
0.32	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.42	GO:0009353	mitochondrial oxoglutarate dehydrogenase complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:1.2.4.2

GO:0004591

sp|Q95T64|PGPLA_DROME
Peptidoglycan-recognition protein LA
Search

0.32	Peptidoglycan-recognition protein LA

0.72	GO:0009253	peptidoglycan catabolic process
0.50	GO:0009617	response to bacterium
0.38	GO:0045087	innate immune response
0.34	GO:0006743	ubiquinone metabolic process
0.34	GO:1901663	quinone biosynthetic process
0.34	GO:0061059	positive regulation of peptidoglycan recognition protein signaling pathway
0.34	GO:0035007	regulation of melanization defense response
0.34	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.33	GO:0019730	antimicrobial humoral response
0.33	GO:0048167	regulation of synaptic plasticity

0.74	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.62	GO:0008270	zinc ion binding
0.38	GO:0042834	peptidoglycan binding
0.34	GO:0016019	peptidoglycan receptor activity
0.32	GO:0046983	protein dimerization activity

0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0031314	extrinsic component of mitochondrial inner membrane
0.33	GO:0016327	apicolateral plasma membrane
0.33	GO:0098793	presynapse

0.74

GO:0008745

tr|Q95T98|Q95T98_DROME
Elongation of very long chain fatty acids protein
Search

0.56	Elongation of very long chain fatty acids protein (Fragment)

0.70	GO:0006633	fatty acid biosynthetic process
0.37	GO:0000038	very long-chain fatty acid metabolic process
0.37	GO:0030148	sphingolipid biosynthetic process

0.83	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.83	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.83	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.83	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.40	GO:0009922	fatty acid elongase activity

0.37

GO:0030176

integral component of endoplasmic reticulum membrane

0.83

EC:2.3.1.199

GO:0102338

tr|Q95TA8|Q95TA8_DROME
AT05092p1
Search

tr|Q95TF4|Q95TF4_DROME
GH01326p
Search

0.74	GO:0006836	neurotransmitter transport
0.54	GO:0055085	transmembrane transport
0.53	GO:0015844	monoamine transport
0.51	GO:0090067	regulation of thalamus size
0.49	GO:0015850	organic hydroxy compound transport
0.48	GO:0015696	ammonium transport
0.45	GO:0046621	negative regulation of organ growth
0.45	GO:0035176	social behavior
0.45	GO:0048854	brain morphogenesis
0.43	GO:0045787	positive regulation of cell cycle

0.76	GO:0005328	neurotransmitter:sodium symporter activity
0.54	GO:0015222	serotonin transmembrane transporter activity
0.47	GO:0050998	nitric-oxide synthase binding
0.44	GO:0017137	Rab GTPase binding
0.42	GO:0005329	dopamine transmembrane transporter activity
0.37	GO:0019811	cocaine binding
0.36	GO:0017075	syntaxin-1 binding
0.36	GO:0051015	actin filament binding
0.36	GO:0017022	myosin binding
0.36	GO:0042302	structural constituent of cuticle

0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0098857	membrane microdomain
0.44	GO:0098793	presynapse
0.42	GO:0120025	plasma membrane bounded cell projection
0.41	GO:0005829	cytosol
0.41	GO:0012505	endomembrane system
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0098588	bounding membrane of organelle

sp|Q95TJ9|CYCG_DROME
Cyclin G
Search

0.47

Cyclin G

0.86	GO:0000711	meiotic DNA repair synthesis
0.84	GO:0007143	female meiotic nuclear division
0.82	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.81	GO:0008593	regulation of Notch signaling pathway
0.79	GO:0045927	positive regulation of growth
0.74	GO:0060429	epithelium development
0.73	GO:0006302	double-strand break repair
0.44	GO:0045859	regulation of protein kinase activity
0.43	GO:0007275	multicellular organism development
0.42	GO:0051301	cell division

0.46	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.40	GO:0005515	protein binding
0.38	GO:0003677	DNA binding
0.36	GO:0001104	RNA polymerase II transcription cofactor activity
0.32	GO:0046872	metal ion binding
0.30	GO:0003824	catalytic activity

0.82	GO:0005700	polytene chromosome
0.40	GO:0005965	protein farnesyltransferase complex
0.36	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043234	protein complex
0.34	GO:0044446	intracellular organelle part
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.30	GO:0016020	membrane

0.46

GO:0016538

tr|Q95TK5|Q95TK5_DROME
CG1635
Search

0.30	Acyl-coa thioesterase

0.59	GO:0006637	acyl-CoA metabolic process
0.49	GO:0006986	response to unfolded protein

0.64

GO:0047617

acyl-CoA hydrolase activity

0.50	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:3.1.2 EC:3.1.2.20

GO:0047617

tr|Q95TL8|Q95TL8_DROME
CG9911, isoform A
Search

ERP44

0.52	Thiol-disulfide isomerase

0.68	GO:0045454	cell redox homeostasis
0.39	GO:0034976	response to endoplasmic reticulum stress
0.37	GO:0006457	protein folding
0.33	GO:0008033	tRNA processing
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0008299	isoprenoid biosynthetic process

0.40	GO:0016853	isomerase activity
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0016783	sulfurtransferase activity
0.34	GO:0008408	3'-5' exonuclease activity
0.32	GO:0003676	nucleic acid binding

0.37	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.40

GO:0016853

sp|Q95TN1|TPC13_DROME
Probable trafficking protein particle complex subunit 13 homolog
Search

TRAPPC13

0.76	Trafficking protein particle complex subunit 13

0.47

GO:0065009

regulation of molecular function

0.55

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.48

GO:0005829

cytosol

sp|Q95TN4|COG4_DROME
Conserved oligomeric Golgi complex subunit 4
Search

0.62	Oligomeric Golgi complex subunit

0.61	GO:0048213	Golgi vesicle prefusion complex stabilization
0.59	GO:0000301	retrograde transport, vesicle recycling within Golgi
0.56	GO:0007030	Golgi organization
0.56	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.41	GO:0048278	vesicle docking
0.40	GO:0006887	exocytosis
0.40	GO:0015031	protein transport
0.35	GO:0006631	fatty acid metabolic process
0.33	GO:0055114	oxidation-reduction process

0.36

GO:0003857

3-hydroxyacyl-CoA dehydrogenase activity

0.80	GO:0017119	Golgi transport complex
0.42	GO:0000139	Golgi membrane
0.34	GO:0005783	endoplasmic reticulum

0.36

EC:1.1.1.35

GO:0003857

tr|Q95TN8|Q95TN8_DROME
Greatwall, isoform A
Search

0.76	Serine/threonine-protein kinase greatwall

0.66	GO:0007144	female meiosis I
0.65	GO:0046602	regulation of mitotic centrosome separation
0.63	GO:0006468	protein phosphorylation
0.62	GO:0040020	regulation of meiotic nuclear division
0.61	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.57	GO:0030261	chromosome condensation
0.56	GO:0000278	mitotic cell cycle
0.41	GO:0018209	peptidyl-serine modification
0.37	GO:0035556	intracellular signal transduction
0.32	GO:0043043	peptide biosynthetic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.65	GO:0071889	14-3-3 protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0048037	cofactor binding
0.32	GO:0003735	structural constituent of ribosome

0.57	GO:0005635	nuclear envelope
0.41	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.69

GO:0004674

tr|Q95TP0|Q95TP0_DROME
LD34582p
Search

0.67	Beta-tubulin folding cofactor C

0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.40	GO:0007021	tubulin complex assembly
0.34	GO:0043461	proton-transporting ATP synthase complex assembly
0.34	GO:0046854	phosphatidylinositol phosphorylation

0.73	GO:0015631	tubulin binding
0.53	GO:0032550	purine ribonucleoside binding
0.53	GO:0019001	guanyl nucleotide binding
0.45	GO:0032555	purine ribonucleotide binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003924	GTPase activity

0.36	GO:0032391	photoreceptor connecting cilium
0.34	GO:0005829	cytosol
0.34	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016020	membrane

sp|Q95TS5|INT9_DROME
Integrator complex subunit 9
Search

0.67	Cleavage and polyadenylation specificity factor

0.83	GO:0016180	snRNA processing
0.45	GO:0043628	ncRNA 3'-end processing
0.35	GO:0006379	mRNA cleavage
0.35	GO:0006378	mRNA polyadenylation
0.34	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.34	GO:0005549	odorant binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.84	GO:0032039	integrator complex
0.37	GO:0005829	cytosol
0.35	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.30	GO:0016020	membrane

tr|Q95TS8|Q95TS8_DROME
LD25288p
Search

0.30

GO:0044425

membrane part

tr|Q95TU2|Q95TU2_DROME
CG6686, isoform A
Search

SNUT1

0.85	Hypoxia associated factor

0.75	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0046579	positive regulation of Ras protein signal transduction
0.42	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.41	GO:0000481	maturation of 5S rRNA
0.38	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0006635	fatty acid beta-oxidation
0.33	GO:0006486	protein glycosylation

0.37	GO:0003723	RNA binding
0.35	GO:0003997	acyl-CoA oxidase activity
0.33	GO:0008378	galactosyltransferase activity

0.42	GO:0071011	precatalytic spliceosome
0.39	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.34	GO:0005777	peroxisome
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.3.3.6

GO:0003997

sp|Q95TU8|UNC5_DROME
Netrin receptor unc-5
Search

0.83	Netrin receptor unc-5

0.85	GO:0038007	netrin-activated signaling pathway
0.69	GO:0007432	salivary gland boundary specification
0.65	GO:0008347	glial cell migration
0.64	GO:0008045	motor neuron axon guidance
0.41	GO:0050919	negative chemotaxis
0.39	GO:0033564	anterior/posterior axon guidance
0.37	GO:0007420	brain development
0.37	GO:0030334	regulation of cell migration
0.37	GO:0043065	positive regulation of apoptotic process
0.34	GO:1901099	negative regulation of signal transduction in absence of ligand

0.85	GO:0005042	netrin receptor activity
0.36	GO:0005515	protein binding

0.34	GO:0005886	plasma membrane
0.33	GO:0043005	neuron projection
0.33	GO:0045202	synapse
0.33	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|Q95TV5|Q95TV5_DROME
Serine/threonine-protein phosphatase
Search

PPP6C

0.46	Serine/threonine-protein phosphatase 6 catalytic subunit

0.70	GO:0006470	protein dephosphorylation
0.49	GO:0061509	asymmetric protein localization to old mitotic spindle pole body
0.49	GO:0031030	negative regulation of septation initiation signaling
0.40	GO:0005977	glycogen metabolic process
0.40	GO:0001878	response to yeast
0.38	GO:2001210	regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway
0.38	GO:1900490	positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity
0.37	GO:0045828	positive regulation of isoprenoid metabolic process
0.37	GO:0051176	positive regulation of sulfur metabolic process
0.37	GO:0051197	positive regulation of coenzyme metabolic process

0.71	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0005515	protein binding
0.32	GO:0008324	cation transmembrane transporter activity
0.31	GO:0016301	kinase activity

0.49	GO:0090443	FAR/SIN/STRIPAK complex
0.42	GO:0005829	cytosol
0.38	GO:0000159	protein phosphatase type 2A complex
0.36	GO:0000790	nuclear chromatin
0.34	GO:0000235	astral microtubule
0.33	GO:0005938	cell cortex
0.33	GO:0000139	Golgi membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.71

GO:0004721

tr|Q95TY2|Q95TY2_DROME
GH22790p
Search

LOC108094005

0.82	sine oculis-binding protein homolog isoform X2

0.77	GO:0007423	sensory organ development
0.55	GO:0050890	cognition
0.55	GO:0007605	sensory perception of sound
0.55	GO:0007626	locomotory behavior
0.55	GO:0048562	embryonic organ morphogenesis
0.34	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:0006024	glycosaminoglycan biosynthetic process
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.66	GO:0008134	transcription factor binding
0.61	GO:0032184	SUMO polymer binding
0.36	GO:0046872	metal ion binding
0.35	GO:0003677	DNA binding
0.34	GO:0015020	glucuronosyltransferase activity

0.46	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:2.4.1.17

GO:0015020

tr|Q95TY8|Q95TY8_DROME
CG6661
Search

0.57	delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.75	GO:0010133	proline catabolic process to glutamate
0.53	GO:0055114	oxidation-reduction process
0.39	GO:0006537	glutamate biosynthetic process
0.34	GO:0007005	mitochondrion organization
0.32	GO:0009450	gamma-aminobutyric acid catabolic process

0.76	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity
0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.41

GO:0005759

mitochondrial matrix

0.76

EC:1.5.1.12

GO:0003842

tr|Q95TZ4|Q95TZ4_DROME
Citrate synthase
Search

0.46	Citrate synthase, mitochondrial

0.70	GO:0006101	citrate metabolic process
0.63	GO:0009060	aerobic respiration
0.36	GO:0005975	carbohydrate metabolic process

0.77

GO:0004108

citrate (Si)-synthase activity

0.41	GO:0005759	mitochondrial matrix
0.30	GO:0044425	membrane part

0.77

EC:2.3.3.1

GO:0004108

tr|Q95U06|Q95U06_DROME
GH16763p
Search

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.45	GO:0010951	negative regulation of endopeptidase activity

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.45	GO:0004867	serine-type endopeptidase inhibitor activity

0.30

GO:0031224

intrinsic component of membrane

0.72

GO:0003755

tr|Q95U32|Q95U32_DROME
GH11867p
Search

0.35	GO:0048869	cellular developmental process
0.30	GO:0008152	metabolic process

0.30

GO:0003824

catalytic activity

0.30

GO:0044425

membrane part

tr|Q95U34|Q95U34_DROME
GH11113p
Search

0.43	N-acetylgalactosamine kinase

0.75	GO:0006012	galactose metabolic process
0.73	GO:0046835	carbohydrate phosphorylation
0.34	GO:0006508	proteolysis

0.80	GO:0004335	galactokinase activity
0.78	GO:0005534	galactose binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0033858	N-acetylgalactosamine kinase activity
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0005509	calcium ion binding
0.33	GO:0008270	zinc ion binding

0.48	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:2.7.1.6	GO:0004335
0.80	KEGG:R01092	GO:0004335

tr|Q95U38|Q95U38_DROME
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Search

0.71	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

0.71	GO:0006099	tricarboxylic acid cycle
0.49	GO:0007291	sperm individualization
0.48	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.75	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.62	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003735	structural constituent of ribosome

0.58	GO:0005739	mitochondrion
0.47	GO:0031463	Cul3-RING ubiquitin ligase complex
0.43	GO:0009361	succinate-CoA ligase complex (ADP-forming)
0.32	GO:0005840	ribosome

0.75	EC:6.2.1.5	GO:0004775
0.75	KEGG:R00405	GO:0004775

tr|Q95U54|Q95U54_DROME
GH06271p
Search

MMS19

0.42	MMS19 nucleotide excision repair protein homolog

0.57	GO:0008643	carbohydrate transport
0.53	GO:0055085	transmembrane transport
0.52	GO:0015992	proton transport
0.42	GO:0016226	iron-sulfur cluster assembly
0.39	GO:0006281	DNA repair
0.38	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0007059	chromosome segregation

0.63	GO:0005351	sugar:proton symporter activity
0.41	GO:0030331	estrogen receptor binding
0.39	GO:0003713	transcription coactivator activity
0.38	GO:0019899	enzyme binding

0.60	GO:0000139	Golgi membrane
0.45	GO:0097361	CIA complex
0.43	GO:0005819	spindle
0.38	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q95U58|Q95U58_DROME
GH05885p
Search

0.97	Monkey king protein (Fragment)

0.44

GO:0006388

tRNA splicing, via endonucleolytic cleavage and ligation

0.62	GO:0016779	nucleotidyltransferase activity
0.42	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.62

GO:0016779

tr|Q95U65|Q95U65_DROME
GH03217p
Search

sp|Q95UN8|M3KSL_DROME
Mitogen-activated protein kinase kinase kinase
Search

SLPR

0.45	Mitogen-activated protein kinase kinase kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0000186	activation of MAPKK activity
0.57	GO:0043507	positive regulation of JUN kinase activity
0.56	GO:0031098	stress-activated protein kinase signaling cascade
0.49	GO:0000187	activation of MAPK activity
0.46	GO:0048804	imaginal disc-derived female genitalia morphogenesis
0.45	GO:0007394	dorsal closure, elongation of leading edge cells
0.45	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.45	GO:0046528	imaginal disc fusion
0.45	GO:0071361	cellular response to ethanol

0.64	GO:0004672	protein kinase activity
0.58	GO:0005057	signal transducer activity, downstream of receptor
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0043425	bHLH transcription factor binding
0.43	GO:0003714	transcription corepressor activity
0.38	GO:0042803	protein homodimerization activity
0.33	GO:0005267	potassium channel activity

0.41	GO:0005938	cell cortex
0.30	GO:0016020	membrane

tr|Q95V50|Q95V50_DROME
Ppr-Y
Search

0.38	dynein regulatory complex subunit 3

0.49	GO:0016336	establishment or maintenance of polarity of larval imaginal disc epithelium
0.47	GO:0016334	establishment or maintenance of polarity of follicular epithelium
0.44	GO:0008285	negative regulation of cell proliferation
0.40	GO:0007165	signal transduction
0.36	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.35	GO:0043666	regulation of phosphoprotein phosphatase activity
0.35	GO:0051457	maintenance of protein location in nucleus
0.35	GO:0060285	cilium-dependent cell motility
0.34	GO:0035308	negative regulation of protein dephosphorylation
0.34	GO:0010923	negative regulation of phosphatase activity

0.37	GO:0072542	protein phosphatase activator activity
0.35	GO:0004865	protein serine/threonine phosphatase inhibitor activity
0.33	GO:0035091	phosphatidylinositol binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.74	GO:0005929	cilium
0.44	GO:0045177	apical part of cell
0.36	GO:0072357	PTW/PP1 phosphatase complex
0.36	GO:0000164	protein phosphatase type 1 complex
0.34	GO:0005634	nucleus
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005856	cytoskeleton
0.33	GO:0005829	cytosol
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0016757

sp|Q95V55|FOXO_DROME
Forkhead box protein O
Search

FOXO

0.66	Forkhead box subgroup O

0.57	GO:0006355	regulation of transcription, DNA-templated
0.54	GO:0006351	transcription, DNA-templated
0.52	GO:0046627	negative regulation of insulin receptor signaling pathway
0.52	GO:0042593	glucose homeostasis
0.51	GO:0010259	multicellular organism aging
0.51	GO:0030308	negative regulation of cell growth
0.50	GO:0042127	regulation of cell proliferation
0.49	GO:0019216	regulation of lipid metabolic process
0.49	GO:0030154	cell differentiation
0.47	GO:0071455	cellular response to hyperoxia

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.44	GO:0008013	beta-catenin binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0051721	protein phosphatase 2A binding
0.38	GO:0000989	transcription factor activity, transcription factor binding
0.38	GO:0003682	chromatin binding
0.38	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|Q95WY3|Q95WY3_DROME
FI04781p
Search

0.71	nucleolar protein 56

0.59	GO:0000154	rRNA modification
0.45	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.45	GO:0006367	transcription initiation from RNA polymerase II promoter
0.43	GO:0007507	heart development

0.66	GO:0030515	snoRNA binding
0.44	GO:0003924	GTPase activity
0.44	GO:0032550	purine ribonucleoside binding
0.43	GO:0019001	guanyl nucleotide binding
0.39	GO:0032555	purine ribonucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008270	zinc ion binding
0.38	GO:0003677	DNA binding

0.71	GO:0031428	box C/D snoRNP complex
0.66	GO:0032040	small-subunit processome
0.30	GO:0031224	intrinsic component of membrane

sp|Q95YI5|US74C_DROME
UDP-sugar transporter UST74c
Search

0.90	UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter

0.51	GO:0015787	UDP-glucuronic acid transmembrane transport
0.49	GO:0008643	carbohydrate transport
0.49	GO:0015790	UDP-xylose transmembrane transport
0.49	GO:1990569	UDP-N-acetylglucosamine transmembrane transport
0.48	GO:0072334	UDP-galactose transmembrane transport
0.48	GO:0015786	UDP-glucose transmembrane transport
0.48	GO:0007367	segment polarity determination
0.47	GO:0007447	imaginal disc pattern formation
0.47	GO:0001745	compound eye morphogenesis
0.47	GO:0007476	imaginal disc-derived wing morphogenesis

0.51	GO:0005461	UDP-glucuronic acid transmembrane transporter activity
0.49	GO:0005464	UDP-xylose transmembrane transporter activity
0.49	GO:0005460	UDP-glucose transmembrane transporter activity
0.49	GO:0005462	UDP-N-acetylglucosamine transmembrane transporter activity
0.48	GO:0005459	UDP-galactose transmembrane transporter activity
0.43	GO:0015297	antiporter activity
0.37	GO:0005458	GDP-mannose transmembrane transporter activity
0.36	GO:0005457	GDP-fucose transmembrane transporter activity
0.35	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.34	GO:0005463	UDP-N-acetylgalactosamine transmembrane transporter activity

0.47	GO:0005797	Golgi medial cisterna
0.47	GO:0031314	extrinsic component of mitochondrial inner membrane
0.35	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0008745

tr|Q960D4|Q960D4_DROME
CG4199, isoform B
Search

0.50	Disulfide oxidoreductase

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0097194	execution phase of apoptosis
0.36	GO:0072114	pronephros morphogenesis
0.32	GO:0007165	signal transduction
0.32	GO:1902600	hydrogen ion transmembrane transport
0.32	GO:0006091	generation of precursor metabolites and energy

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.54	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0015078	hydrogen ion transmembrane transporter activity

0.39	GO:0005783	endoplasmic reticulum
0.39	GO:0005829	cytosol
0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.33	GO:0045277	respiratory chain complex IV
0.33	GO:0098798	mitochondrial protein complex
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

tr|Q960E4|Q960E4_DROME
CG8929, isoform A
Search

0.38	basic salivary proline-rich protein 2 isoform X2

0.44	GO:0006397	mRNA processing
0.43	GO:0018993	somatic sex determination
0.42	GO:0048806	genitalia development
0.42	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.42	GO:0048749	compound eye development
0.41	GO:0042752	regulation of circadian rhythm
0.41	GO:0035082	axoneme assembly
0.40	GO:0043068	positive regulation of programmed cell death
0.39	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

0.56	GO:0003723	RNA binding
0.37	GO:0008270	zinc ion binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005681	spliceosomal complex
0.30	GO:0016020	membrane

sp|Q960E8|TF2H1_DROME
General transcription factor IIH subunit 1
Search

0.75	General transcription factor IIH subunit

0.73	GO:0006289	nucleotide-excision repair
0.58	GO:0006351	transcription, DNA-templated
0.52	GO:0009411	response to UV
0.41	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain
0.38	GO:0001120	protein-DNA complex remodeling
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II

0.40	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.38	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0000990	transcription factor activity, core RNA polymerase binding

0.81	GO:0000439	core TFIIH complex
0.54	GO:0005675	holo TFIIH complex

0.40

EC:2.7.11.23

GO:0008353

tr|Q960E9|Q960E9_DROME
SD04526p
Search

0.53	GO:0006397	mRNA processing
0.39	GO:0000028	ribosomal small subunit assembly
0.39	GO:0007411	axon guidance
0.37	GO:0000413	protein peptidyl-prolyl isomerization
0.35	GO:0006468	protein phosphorylation

0.38	GO:0003723	RNA binding
0.37	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0003735	structural constituent of ribosome
0.35	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0022627	cytosolic small ribosomal subunit
0.38	GO:0016607	nuclear speck
0.37	GO:0000790	nuclear chromatin

0.37

GO:0003755

tr|Q960F7|Q960F7_DROME
CG2017, isoform A
Search

0.37	Elongation factor Tu

0.42	GO:0006414	translational elongation
0.34	GO:0002576	platelet degranulation
0.33	GO:0009116	nucleoside metabolic process
0.33	GO:0009165	nucleotide biosynthetic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003746	translation elongation factor activity
0.34	GO:0004749	ribose phosphate diphosphokinase activity
0.33	GO:0005515	protein binding
0.33	GO:0000287	magnesium ion binding

0.39	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0031093	platelet alpha granule lumen
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.34	EC:2.7.6.1	GO:0004749
0.34	KEGG:R01049	GO:0004749

tr|Q960G1|Q960G1_DROME
CG1074
Search

0.32	Methyltransferase

0.63	GO:0032259	methylation
0.34	GO:0048193	Golgi vesicle transport
0.34	GO:0043087	regulation of GTPase activity
0.34	GO:0051382	kinetochore assembly
0.33	GO:0000278	mitotic cell cycle

0.63	GO:0008168	methyltransferase activity
0.51	GO:0003676	nucleic acid binding
0.33	GO:0046982	protein heterodimerization activity
0.32	GO:0016787	hydrolase activity

0.30

GO:0016020

membrane

0.63

GO:0008168

tr|Q960J7|Q960J7_DROME
LD47616p
Search

0.55

GO:0003677

DNA binding

tr|Q960J9|Q960J9_DROME
LD47544p
Search

0.53	GO:0032259	methylation
0.43	GO:0005975	carbohydrate metabolic process

0.53	GO:0008168	methyltransferase activity
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.43	GO:0016788	hydrolase activity, acting on ester bonds

0.53

GO:0008168

tr|Q960K3|Q960K3_DROME
CG1103, isoform A
Search

0.19	Putative conserved plasma membrane protein (Fragment)

0.36	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|Q960M4|Q960M4_DROME
LD45324p
Search

0.38	Peroxiredoxin, mitochondrial

0.68	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0008340	determination of adult lifespan
0.45	GO:0043066	negative regulation of apoptotic process
0.45	GO:0042744	hydrogen peroxide catabolic process
0.43	GO:0045824	negative regulation of innate immune response
0.43	GO:0006979	response to oxidative stress
0.43	GO:0098869	cellular oxidant detoxification
0.40	GO:0031101	fin regeneration
0.37	GO:0006606	protein import into nucleus

0.54	GO:0016491	oxidoreductase activity
0.43	GO:0016209	antioxidant activity
0.37	GO:0061608	nuclear import signal receptor activity
0.36	GO:0008565	protein transporter activity
0.36	GO:0001016	RNA polymerase III regulatory region DNA binding
0.36	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.34	GO:0005102	receptor binding
0.34	GO:0046983	protein dimerization activity
0.34	GO:0003707	steroid hormone receptor activity
0.33	GO:0051082	unfolded protein binding

0.42	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.40	GO:0005739	mitochondrion
0.36	GO:0005777	peroxisome
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0031410	cytoplasmic vesicle

0.54

GO:0016491

sp|Q960N3|CORT_DROME
Protein cortex
Search

0.83	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.73	GO:0007147	female meiosis II
0.73	GO:0051440	regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle
0.72	GO:0007144	female meiosis I
0.70	GO:0007343	egg activation
0.66	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.45	GO:0007279	pole cell formation
0.43	GO:0045143	homologous chromosome segregation
0.42	GO:0048477	oogenesis
0.36	GO:0007062	sister chromatid cohesion

0.83	GO:0010997	anaphase-promoting complex binding
0.82	GO:0097027	ubiquitin-protein transferase activator activity
0.36	GO:0031491	nucleosome binding
0.35	GO:0003714	transcription corepressor activity

0.43	GO:0005737	cytoplasm
0.37	GO:0030915	Smc5-Smc6 complex
0.35	GO:0000790	nuclear chromatin
0.30	GO:0016020	membrane

tr|Q960Q8|Q960Q8_DROME
CG3511, isoform A
Search

PPWD1

0.66	Peptidylprolyl isomerase domain and WD repeat-containing protein 1

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.36	GO:0008380	RNA splicing
0.36	GO:0006397	mRNA processing
0.33	GO:0006457	protein folding

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0008289	lipid binding

0.48	GO:0071013	catalytic step 2 spliceosome
0.47	GO:0016604	nuclear body
0.30	GO:0044425	membrane part

0.72

GO:0003755

tr|Q960Q9|Q960Q9_DROME
CG2712
Search

0.42	zinc finger protein 26

0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0007050	cell cycle arrest
0.33	GO:0008285	negative regulation of cell proliferation
0.33	GO:1902680	positive regulation of RNA biosynthetic process
0.32	GO:0032259	methylation
0.32	GO:0006468	protein phosphorylation

0.51	GO:0003676	nucleic acid binding
0.47	GO:0008270	zinc ion binding
0.40	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding
0.36	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.47	GO:0005634	nucleus
0.39	GO:0000785	chromatin
0.38	GO:0031974	membrane-enclosed lumen
0.33	GO:0015630	microtubule cytoskeleton
0.32	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008168

sp|Q960T2|SAP47_DROME
Synapse-associated protein of 47 kDa
Search

LOC108096643

0.88	Synapse-associated protein of 47 kDa

0.78	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.74	GO:0008306	associative learning
0.43	GO:0098916	anterograde trans-synaptic signaling

0.52	GO:0008270	zinc ion binding
0.44	GO:0003676	nucleic acid binding

0.66

GO:0045202

synapse

tr|Q960U8|Q960U8_DROME
O-acyltransferase
Search

0.62	O-acyltransferase

0.82	GO:0019432	triglyceride biosynthetic process
0.55	GO:0045477	regulation of nurse cell apoptotic process
0.53	GO:0010888	negative regulation of lipid storage
0.38	GO:0048477	oogenesis
0.34	GO:0006418	tRNA aminoacylation for protein translation
0.33	GO:0006508	proteolysis

0.81	GO:0004144	diacylglycerol O-acyltransferase activity
0.34	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003676	nucleic acid binding

0.65	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.81

EC:2.3.1.20

GO:0004144

sp|Q960V3|MILT_DROME
Trafficking kinesin-binding protein milt
Search

0.80	Trafficking kinesin-binding protein milt

0.89	GO:0007287	Nebenkern assembly
0.87	GO:0030382	sperm mitochondrion organization
0.87	GO:0019896	axonal transport of mitochondrion
0.86	GO:0007310	oocyte dorsal/ventral axis specification
0.84	GO:0048311	mitochondrion distribution

0.85	GO:0017022	myosin binding
0.75	GO:0003777	microtubule motor activity

0.85	GO:1904115	axon cytoplasm
0.61	GO:0005739	mitochondrion

tr|Q960W0|Q960W0_DROME
LD32258p
Search

0.71	FAST kinase domain-containing protein 1

0.61

GO:0006468

protein phosphorylation

0.62

GO:0004672

protein kinase activity

0.30

GO:0031224

intrinsic component of membrane

sp|Q960W6|FACR3_DROME
Putative fatty acyl-CoA reductase CG8306
Search

0.56	Fatty acyl-CoA reductase

0.63	GO:0006629	lipid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0010025	wax biosynthetic process
0.39	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.38	GO:0016310	phosphorylation
0.33	GO:0006397	mRNA processing
0.33	GO:0090501	RNA phosphodiester bond hydrolysis
0.32	GO:0006464	cellular protein modification process

0.83	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.83	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.39	GO:0016301	kinase activity
0.33	GO:0050062	long-chain-fatty-acyl-CoA reductase activity
0.33	GO:0004540	ribonuclease activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005777	peroxisome
0.34	GO:0012505	endomembrane system
0.33	GO:0031903	microbody membrane
0.33	GO:0031301	integral component of organelle membrane

0.33

EC:1.2.1.50

GO:0050062

sp|Q960X4|TIP60_DROME
Histone acetyltransferase Tip60
Search

KAT5

0.55	Histone acetyltransferase

0.78	GO:0016573	histone acetylation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.49	GO:2000331	regulation of terminal button organization
0.49	GO:0032703	negative regulation of interleukin-2 production
0.48	GO:0071392	cellular response to estradiol stimulus
0.48	GO:1901985	positive regulation of protein acetylation
0.47	GO:0043524	negative regulation of neuron apoptotic process

0.80	GO:0004402	histone acetyltransferase activity
0.47	GO:0070491	repressing transcription factor binding
0.46	GO:0003713	transcription coactivator activity
0.35	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity
0.35	GO:0050681	androgen receptor binding
0.34	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding

0.79	GO:0035267	NuA4 histone acetyltransferase complex
0.48	GO:0005705	polytene chromosome interband
0.47	GO:0000812	Swr1 complex
0.44	GO:0005667	transcription factor complex
0.44	GO:0005730	nucleolus
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

0.80

GO:0004402

sp|Q960X8|HRS_DROME
Hepatocyte growth factor-regulated tyrosine kinase substrate
Search

0.90	Hepatocyte growth factor-regulated tyrosine kinase substrate

0.67	GO:0046907	intracellular transport
0.66	GO:0070727	cellular macromolecule localization
0.63	GO:0015031	protein transport
0.55	GO:2000366	positive regulation of STAT protein import into nucleus
0.55	GO:0045752	positive regulation of Toll signaling pathway
0.55	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.55	GO:0061357	positive regulation of Wnt protein secretion
0.55	GO:1990182	exosomal secretion
0.54	GO:0008293	torso signaling pathway
0.54	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway

0.53	GO:0046872	metal ion binding
0.50	GO:0043130	ubiquitin binding
0.47	GO:0016301	kinase activity
0.33	GO:0044389	ubiquitin-like protein ligase binding
0.33	GO:0019904	protein domain specific binding
0.32	GO:0016853	isomerase activity
0.32	GO:0003676	nucleic acid binding

0.70	GO:0048471	perinuclear region of cytoplasm
0.67	GO:0005938	cell cortex
0.55	GO:0033565	ESCRT-0 complex
0.46	GO:0005829	cytosol
0.39	GO:0010008	endosome membrane
0.37	GO:0008021	synaptic vesicle
0.34	GO:0005771	multivesicular body
0.33	GO:0005769	early endosome
0.33	GO:0005764	lysosome
0.33	GO:0005819	spindle

0.32

GO:0016853

tr|Q960Y8|Q960Y8_DROME
Aluminum tubes, isoform G
Search

RRBP1

0.60	Ribosome-binding protein 1

0.48	GO:0015031	protein transport
0.41	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process
0.36	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation
0.36	GO:0001649	osteoblast differentiation
0.33	GO:0007165	signal transduction
0.33	GO:0007062	sister chromatid cohesion
0.33	GO:0030261	chromosome condensation

0.42	GO:0004872	receptor activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0005545	1-phosphatidylinositol binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.58	GO:0030176	integral component of endoplasmic reticulum membrane
0.41	GO:0005840	ribosome
0.35	GO:0030141	secretory granule
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005615	extracellular space
0.33	GO:0030014	CCR4-NOT complex
0.33	GO:0005634	nucleus
0.32	GO:0030136	clathrin-coated vesicle

0.33

GO:0004674

sp|Q960Z0|KI10A_DROME
Kinesin-like protein Klp10A
Search

0.74	GO:0007018	microtubule-based movement
0.60	GO:0007019	microtubule depolymerization
0.57	GO:0051303	establishment of chromosome localization
0.55	GO:0007163	establishment or maintenance of cell polarity
0.55	GO:0000070	mitotic sister chromatid segregation
0.54	GO:0061867	establishment of mitotic spindle asymmetry
0.52	GO:0007057	spindle assembly involved in female meiosis I
0.52	GO:0051295	establishment of meiotic spindle localization
0.52	GO:0045167	asymmetric protein localization involved in cell fate determination
0.49	GO:0008608	attachment of spindle microtubules to kinetochore

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0016887	ATPase activity
0.35	GO:0019237	centromeric DNA binding

0.73	GO:0005874	microtubule
0.54	GO:0000775	chromosome, centromeric region
0.52	GO:0090619	meiotic spindle pole
0.51	GO:0030981	cortical microtubule cytoskeleton
0.50	GO:0005818	aster
0.50	GO:0097431	mitotic spindle pole
0.47	GO:0005813	centrosome
0.44	GO:0005871	kinesin complex
0.36	GO:0000793	condensed chromosome
0.34	GO:0005634	nucleus

0.43

GO:0016887

tr|Q961B3|Q961B3_DROME
CG2277, isoform A
Search

0.89	5'-nucleotidase domain-containing protein 1

0.54

GO:0016311

dephosphorylation

0.61

GO:0008253

5'-nucleotidase activity

0.53	GO:1990904	ribonucleoprotein complex
0.41	GO:0044424	intracellular part

0.61

EC:3.1.3.5

GO:0008253

tr|Q961B9|Q961B9_DROME
CG5027
Search

0.33	Thioredoxin domain-containing protein 10

0.68	GO:0045454	cell redox homeostasis
0.39	GO:0034976	response to endoplasmic reticulum stress
0.38	GO:0006457	protein folding
0.34	GO:0030097	hemopoiesis
0.32	GO:0001510	RNA methylation
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0036508	protein alpha-1,2-demannosylation
0.32	GO:0035977	protein deglycosylation involved in glycoprotein catabolic process
0.32	GO:1904587	response to glycoprotein
0.32	GO:0006396	RNA processing

0.49	GO:0016853	isomerase activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0019153	protein-disulfide reductase (glutathione) activity
0.33	GO:0015036	disulfide oxidoreductase activity
0.32	GO:0008173	RNA methyltransferase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0051082	unfolded protein binding

0.38	GO:0005783	endoplasmic reticulum
0.33	GO:0009986	cell surface
0.32	GO:0005774	vacuolar membrane
0.32	GO:0043233	organelle lumen
0.32	GO:0009507	chloroplast
0.31	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0016853

tr|Q961C5|Q961C5_DROME
Alphabet, isoform E
Search

ALPH

0.37	Putative serine/threonine protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.50	GO:0045678	positive regulation of R7 cell differentiation
0.50	GO:1901562	response to paraquat
0.49	GO:0046528	imaginal disc fusion
0.49	GO:0010225	response to UV-C
0.48	GO:1902532	negative regulation of intracellular signal transduction
0.48	GO:1900744	regulation of p38MAPK cascade
0.48	GO:0007391	dorsal closure
0.47	GO:0001745	compound eye morphogenesis
0.47	GO:0007476	imaginal disc-derived wing morphogenesis

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.72	GO:0030145	manganese ion binding
0.64	GO:0000287	magnesium ion binding
0.34	GO:0003972	RNA ligase (ATP) activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005730	nucleolus
0.39	GO:0005829	cytosol
0.34	GO:0072669	tRNA-splicing ligase complex
0.33	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.34

EC:6.5.1.3

GO:0003972

tr|Q961C8|Q961C8_DROME
LD22649p
Search

LOC108092142

0.32	homeobox protein 5 isoform X1

0.58	GO:0060271	cilium assembly
0.39	GO:0006368	transcription elongation from RNA polymerase II promoter
0.38	GO:0016570	histone modification

0.55	GO:0008017	microtubule binding
0.49	GO:0003677	DNA binding

0.39	GO:0016593	Cdc73/Paf1 complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q961C9|TNG11_DROME
Transport and Golgi organization protein 11
Search

0.88	Mitochondrial and peroxisomal fission factor Mff

0.56	GO:0009306	protein secretion
0.36	GO:0006104	succinyl-CoA metabolic process
0.35	GO:0006099	tricarboxylic acid cycle

0.36	GO:0004776	succinate-CoA ligase (GDP-forming) activity
0.35	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0000287	magnesium ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0005741	mitochondrial outer membrane
0.39	GO:0042579	microbody
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:6.2.1.4	GO:0004776
0.36	KEGG:R00432	GO:0004776

tr|Q961D1|Q961D1_DROME
Cyclin K, isoform A
Search

0.78	CDK9 kinase-activating protein cyclin T

0.51	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.48	GO:0045787	positive regulation of cell cycle
0.47	GO:0044828	negative regulation by host of viral genome replication
0.47	GO:2001163	regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues
0.45	GO:0071156	regulation of cell cycle arrest
0.45	GO:1904031	positive regulation of cyclin-dependent protein kinase activity
0.44	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.44	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.44	GO:0010948	negative regulation of cell cycle process
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II

0.45	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.45	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.45	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.43	GO:0019901	protein kinase binding

0.60	GO:0005634	nucleus
0.49	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.45

EC:2.7.11.22

GO:0004693

tr|Q961D3|Q961D3_DROME
LD17001p
Search

0.25	multidrug resistance-associated protein 4

0.55	GO:0055085	transmembrane transport
0.44	GO:0010043	response to zinc ion
0.42	GO:0046688	response to copper ion
0.40	GO:0042060	wound healing
0.38	GO:0034059	response to anoxia
0.37	GO:0001666	response to hypoxia
0.37	GO:0048190	wing disc dorsal/ventral pattern formation
0.37	GO:0008340	determination of adult lifespan
0.37	GO:0006260	DNA replication
0.35	GO:0006979	response to oxidative stress

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.38

GO:0005887

integral component of plasma membrane

sp|Q961D9|BCL9_DROME
Protein BCL9 homolog
Search

0.88	GO:0007491	sternite morphogenesis
0.86	GO:0035223	leg disc pattern formation
0.86	GO:0035293	chitin-based larval cuticle pattern formation
0.86	GO:0007367	segment polarity determination
0.85	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.83	GO:0060070	canonical Wnt signaling pathway
0.83	GO:0030177	positive regulation of Wnt signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.45	GO:0005515	protein binding
0.36	GO:0003713	transcription coactivator activity
0.32	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.86	GO:1990907	beta-catenin-TCF complex
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.39	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

sp|Q961G1|COG3_DROME
Conserved oligomeric Golgi complex subunit 3
Search

COG3

0.83	Component of oligomeric golgi complex 3

0.69	GO:0006886	intracellular protein transport
0.52	GO:0007112	male meiosis cytokinesis
0.51	GO:0033227	dsRNA transport
0.49	GO:0006891	intra-Golgi vesicle-mediated transport
0.48	GO:0007030	Golgi organization
0.46	GO:0006888	ER to Golgi vesicle-mediated transport
0.45	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.44	GO:0050821	protein stabilization
0.43	GO:0043413	macromolecule glycosylation
0.43	GO:0009101	glycoprotein biosynthetic process

0.45	GO:0008565	protein transporter activity
0.32	GO:0003677	DNA binding

0.82	GO:0005801	cis-Golgi network
0.55	GO:0017119	Golgi transport complex
0.41	GO:0005829	cytosol
0.38	GO:0000139	Golgi membrane
0.37	GO:0005886	plasma membrane
0.34	GO:0031985	Golgi cisterna
0.30	GO:0016021	integral component of membrane

tr|Q961H2|Q961H2_DROME
GH23453p
Search

0.33	proton-coupled folate transporter

0.57	GO:0097254	renal tubular secretion
0.55	GO:0055085	transmembrane transport
0.46	GO:0009636	response to toxic substance
0.35	GO:0007034	vacuolar transport

0.50

GO:0005215

transporter activity

0.33	GO:1990904	ribonucleoprotein complex
0.32	GO:0044424	intracellular part
0.30	GO:0044425	membrane part

tr|Q961I8|Q961I8_DROME
GH21465p
Search

0.11	prolyl 4-hydroxylase subunit alpha-1

0.83	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0032504	multicellular organism reproduction

0.84	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.74	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.63	GO:0005506	iron ion binding

0.69	GO:0005783	endoplasmic reticulum
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:1.14.11.2	GO:0004656
0.84	KEGG:R03219	GO:0004656

tr|Q961J0|Q961J0_DROME
GH21160p
Search

0.46	Glyoxylase

0.51	GO:0048337	positive regulation of mesodermal cell fate specification
0.50	GO:0045138	nematode male tail tip morphogenesis
0.49	GO:0040018	positive regulation of multicellular organism growth
0.47	GO:0007179	transforming growth factor beta receptor signaling pathway
0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:0031929	TOR signaling
0.46	GO:0030522	intracellular receptor signaling pathway
0.45	GO:0009410	response to xenobiotic stimulus
0.45	GO:0006366	transcription by RNA polymerase II
0.44	GO:1902680	positive regulation of RNA biosynthetic process

0.57	GO:0003713	transcription coactivator activity
0.49	GO:0001106	RNA polymerase II transcription corepressor activity
0.49	GO:0004874	aryl hydrocarbon receptor activity
0.48	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.44	GO:0016874	ligase activity
0.42	GO:0046983	protein dimerization activity
0.42	GO:0003676	nucleic acid binding
0.40	GO:0003700	DNA binding transcription factor activity

0.48	GO:0034751	aryl hydrocarbon receptor complex
0.47	GO:0031931	TORC1 complex
0.44	GO:0005634	nucleus
0.43	GO:0019013	viral nucleocapsid
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.44

GO:0016874

tr|Q961J5|Q961J5_DROME
CG3790
Search

0.63	Organic cation transporter

0.55	GO:0055085	transmembrane transport
0.52	GO:0045471	response to ethanol
0.37	GO:0015711	organic anion transport
0.35	GO:0006508	proteolysis
0.33	GO:0030001	metal ion transport
0.32	GO:0008643	carbohydrate transport
0.31	GO:0006351	transcription, DNA-templated

0.57	GO:0022857	transmembrane transporter activity
0.36	GO:0004222	metalloendopeptidase activity
0.34	GO:0046872	metal ion binding
0.31	GO:0003677	DNA binding

0.31	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004222

tr|Q961J8|Q961J8_DROME
CG8560, isoform A
Search

0.45	Zinc carboxypeptidase

0.61	GO:0006508	proteolysis
0.32	GO:0006836	neurotransmitter transport
0.31	GO:0055085	transmembrane transport

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.32	GO:0005328	neurotransmitter:sodium symporter activity

0.37	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.4.17

GO:0004181

tr|Q961K4|Q961K4_DROME
GH19118p
Search

0.10	Hexose transporter HXT17

0.53	GO:0055085	transmembrane transport
0.33	GO:0051301	cell division
0.33	GO:0007049	cell cycle
0.33	GO:0019538	protein metabolic process
0.32	GO:0050896	response to stimulus
0.32	GO:0023052	signaling
0.32	GO:0007154	cell communication
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0043412	macromolecule modification
0.32	GO:0016310	phosphorylation

0.55	GO:0022857	transmembrane transporter activity
0.37	GO:0005544	calcium-dependent phospholipid binding
0.36	GO:0005509	calcium ion binding
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016853	isomerase activity
0.32	GO:0008658	penicillin binding
0.32	GO:0003743	translation initiation factor activity
0.32	GO:0017171	serine hydrolase activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0016301	kinase activity

0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0016853

tr|Q961K6|Q961K6_DROME
CG3829, isoform A
Search

0.57	scavenger receptor class B member 1

0.35

GO:0060089

molecular transducer activity

0.37	GO:0005764	lysosome
0.30	GO:0044425	membrane part

tr|Q961L4|Q961L4_DROME
Death resistor Adh domain containing target, isoform C
Search

0.43	Zinc-dependent alcohol dehydrogenase

0.55	GO:0071361	cellular response to ethanol
0.52	GO:0001666	response to hypoxia
0.52	GO:0055114	oxidation-reduction process

0.53

GO:0016491

oxidoreductase activity

0.30

GO:0031224

intrinsic component of membrane

0.53

GO:0016491

tr|Q961L5|Q961L5_DROME
GH17930p
Search

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.36	GO:0042981	regulation of apoptotic process

0.72

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

0.30

GO:0031224

intrinsic component of membrane

0.72

GO:0003755

tr|Q961L8|Q961L8_DROME
GH17661p
Search

0.13	O-acetyl-ADP-ribose deacetylase 1

0.64	GO:0042278	purine nucleoside metabolic process
0.46	GO:0080009	mRNA methylation
0.44	GO:0006508	proteolysis
0.43	GO:0001172	transcription, RNA-templated
0.43	GO:0039694	viral RNA genome replication
0.41	GO:0006396	RNA processing
0.39	GO:0006351	transcription, DNA-templated

0.60	GO:0001883	purine nucleoside binding
0.48	GO:0070001	aspartic-type peptidase activity
0.46	GO:0008174	mRNA methyltransferase activity
0.45	GO:0004175	endopeptidase activity
0.43	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.40	GO:0003723	RNA binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.46

GO:0008174

tr|Q961N0|Q961N0_DROME
Alpha-Esterase-2, isoform A
Search

0.33	Carboxylic ester hydrolase

0.30

GO:0008152

metabolic process

0.59

GO:0052689

carboxylic ester hydrolase activity

0.30

GO:0044425

membrane part

0.59	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.59	KEGG:R00630	GO:0052689

tr|Q961Q8|Q961Q8_DROME
GH10454p
Search

0.58	Hemoglobin subunit alpha-A

0.43

GO:0016310

phosphorylation

0.50

GO:0016740

transferase activity

0.30

GO:0044425

membrane part

0.50

GO:0016740

tr|Q961Q9|Q961Q9_DROME
CG5687, isoform A
Search

0.39	Sodium-coupled monocarboxylate transporter

0.55	GO:0055085	transmembrane transport
0.37	GO:0051780	behavioral response to nutrient
0.36	GO:0008343	adult feeding behavior
0.32	GO:0006812	cation transport
0.32	GO:0045666	positive regulation of neuron differentiation
0.32	GO:0035023	regulation of Rho protein signal transduction
0.32	GO:0043547	positive regulation of GTPase activity
0.32	GO:0000902	cell morphogenesis
0.32	GO:0000910	cytokinesis

0.57	GO:0022857	transmembrane transporter activity
0.32	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.32	GO:0008144	drug binding
0.32	GO:0046872	metal ion binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005096	GTPase activator activity
0.31	GO:0003677	DNA binding

0.31	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32

GO:0016887

tr|Q961R9|Q961R9_DROME
CG6126
Search

0.59	Organic Cation Transporter

0.55	GO:0055085	transmembrane transport
0.36	GO:0071702	organic substance transport
0.36	GO:0006820	anion transport
0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0008340	determination of adult lifespan
0.32	GO:0006836	neurotransmitter transport
0.32	GO:0006812	cation transport

0.57	GO:0022857	transmembrane transporter activity
0.35	GO:0005044	scavenger receptor activity
0.32	GO:0005326	neurotransmitter transporter activity
0.30	GO:0003824	catalytic activity

0.35

GO:0005887

integral component of plasma membrane

tr|Q961T8|Q961T8_DROME
Defective proboscis extension response 5, isoform A
Search

0.50	Defective proboscis extension response

0.70	GO:0050808	synapse organization
0.44	GO:0007606	sensory perception of chemical stimulus
0.34	GO:0016310	phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.37	GO:0005515	protein binding
0.35	GO:0016301	kinase activity
0.32	GO:0016491	oxidoreductase activity

0.40	GO:0005887	integral component of plasma membrane
0.36	GO:0032589	neuron projection membrane

0.32

GO:0016491

tr|Q961T9|Q961T9_DROME
GH07914p
Search

tr|Q961U0|Q961U0_DROME
GH07804p
Search

0.71	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

0.73	GO:0009312	oligosaccharide biosynthetic process
0.55	GO:0006487	protein N-linked glycosylation

0.86

GO:0008455

alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

0.80	GO:0005795	Golgi stack
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.4.1.143

GO:0008455

tr|Q961W5|Q961W5_DROME
GH02452p
Search

0.51	cytosol aminopeptidase

0.61	GO:0006508	proteolysis
0.44	GO:0007498	mesoderm development
0.34	GO:0032504	multicellular organism reproduction
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0006468	protein phosphorylation

0.74	GO:0008235	metalloexopeptidase activity
0.73	GO:0030145	manganese ion binding
0.71	GO:0004177	aminopeptidase activity
0.37	GO:0003995	acyl-CoA dehydrogenase activity
0.35	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0004672	protein kinase activity

0.49	GO:0005737	cytoplasm
0.34	GO:0005615	extracellular space

0.71

GO:0004177

tr|Q961W9|Q961W9_DROME
GH01761p
Search

tr|Q962I0|Q962I0_DROME
LD47926p
Search

0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.56	GO:0007525	somatic muscle development
0.55	GO:0007520	myoblast fusion
0.54	GO:0007519	skeletal muscle tissue development
0.50	GO:0045893	positive regulation of transcription, DNA-templated
0.50	GO:0010817	regulation of hormone levels
0.37	GO:1990798	pancreas regeneration
0.37	GO:0003323	type B pancreatic cell development
0.37	GO:0006366	transcription by RNA polymerase II
0.36	GO:0045892	negative regulation of transcription, DNA-templated

0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.37	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0000987	proximal promoter sequence-specific DNA binding
0.33	GO:0046872	metal ion binding

0.58	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.33	GO:0005667	transcription factor complex

tr|Q962S2|Q962S2_DROME
GEO12578p1
Search

RPL41

0.97	Ribosomal protein L41 containing protein, expressed

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0016070	RNA metabolic process
0.34	GO:0034654	nucleobase-containing compound biosynthetic process
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0034655	nucleobase-containing compound catabolic process
0.33	GO:0044265	cellular macromolecule catabolic process

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003730	mRNA 3'-UTR binding
0.40	GO:0048027	mRNA 5'-UTR binding
0.37	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0003677	DNA binding
0.32	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.40	GO:0044445	cytosolic part
0.40	GO:0005844	polysome
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005694	chromosome
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:2.7.7.6

GO:0003899

sp|Q967D7|TUTL_DROME
Protein turtle
Search

0.41	GO:0045467	R7 cell development
0.41	GO:0007414	axonal defasciculation
0.41	GO:0007629	flight behavior
0.41	GO:0070593	dendrite self-avoidance
0.40	GO:0016199	axon midline choice point recognition
0.40	GO:0008039	synaptic target recognition
0.40	GO:0007638	mechanosensory behavior
0.40	GO:0030537	larval behavior
0.40	GO:0048814	regulation of dendrite morphogenesis
0.38	GO:0098609	cell-cell adhesion

0.40	GO:0098632	cell-cell adhesion mediator activity
0.31	GO:0008168	methyltransferase activity

0.37	GO:0005887	integral component of plasma membrane
0.33	GO:0005576	extracellular region

0.31

GO:0008168

tr|Q967S0|Q967S0_DROME
Amidophosphoribosyltransferase
Search

0.52	Amidophosphoribosyltransferase

0.75	GO:0009113	purine nucleobase biosynthetic process
0.68	GO:0006189	'de novo' IMP biosynthetic process
0.66	GO:0009116	nucleoside metabolic process
0.45	GO:0040016	embryonic cleavage
0.44	GO:0008340	determination of adult lifespan
0.43	GO:0048477	oogenesis
0.36	GO:0006541	glutamine metabolic process
0.35	GO:0007595	lactation
0.35	GO:0031100	animal organ regeneration
0.35	GO:0060135	maternal process involved in female pregnancy

0.79	GO:0004044	amidophosphoribosyltransferase activity
0.62	GO:0051536	iron-sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.32	GO:0003723	RNA binding

0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:2.4.2.14	GO:0004044
0.79	KEGG:R01072	GO:0004044

sp|Q99323|MYSN_DROME
Myosin heavy chain, non-muscle
Search

0.61	Myosin heavy chain, non-muscle

0.71	GO:0007018	microtubule-based movement
0.43	GO:0046663	dorsal closure, leading edge cell differentiation
0.43	GO:0031036	myosin II filament assembly
0.43	GO:0007496	anterior midgut development
0.43	GO:0060289	compartment boundary maintenance
0.43	GO:0046664	dorsal closure, amnioserosa morphology change
0.43	GO:0007395	dorsal closure, spreading of leading edge cells
0.42	GO:0035277	spiracle morphogenesis, open tracheal system
0.42	GO:0016318	ommatidial rotation
0.42	GO:0035017	cuticle pattern formation

0.73	GO:0003779	actin binding
0.73	GO:0003774	motor activity
0.72	GO:0008017	microtubule binding
0.63	GO:0032403	protein complex binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0032027	myosin light chain binding
0.39	GO:0042802	identical protein binding

0.77	GO:0016459	myosin complex
0.42	GO:0045179	apical cortex
0.41	GO:0032154	cleavage furrow
0.41	GO:0044291	cell-cell contact zone
0.41	GO:0005826	actomyosin contractile ring
0.41	GO:0030018	Z disc
0.40	GO:0031252	cell leading edge
0.36	GO:0030117	membrane coat
0.32	GO:0005929	cilium
0.31	GO:0005829	cytosol

0.32

GO:0016887

sp|Q9BIR7|HSP75_DROME
Major heat shock 70 kDa protein Bc
Search

0.58	Major heat shock 70 kDa protein Bbb

0.43	GO:0008340	determination of adult lifespan
0.43	GO:0035080	heat shock-mediated polytene chromosome puffing
0.42	GO:0042594	response to starvation
0.40	GO:0001666	response to hypoxia
0.39	GO:0006986	response to unfolded protein
0.34	GO:0010918	positive regulation of mitochondrial membrane potential
0.34	GO:0070584	mitochondrion morphogenesis
0.34	GO:0000422	autophagy of mitochondrion
0.33	GO:0009636	response to toxic substance
0.33	GO:0006457	protein folding

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0051082	unfolded protein binding
0.33	GO:0043565	sequence-specific DNA binding

0.33

GO:0005739

mitochondrion

0.34

GO:0032440

sp|Q9BIS2|HSP73_DROME
Major heat shock 70 kDa protein Bb
Search

0.58	Major heat shock 70 kDa protein Bbb

0.43	GO:0008340	determination of adult lifespan
0.43	GO:0035080	heat shock-mediated polytene chromosome puffing
0.42	GO:0042594	response to starvation
0.40	GO:0001666	response to hypoxia
0.39	GO:0006986	response to unfolded protein
0.34	GO:0010918	positive regulation of mitochondrial membrane potential
0.34	GO:0070584	mitochondrion morphogenesis
0.34	GO:0000422	autophagy of mitochondrion
0.33	GO:0009636	response to toxic substance
0.33	GO:0006457	protein folding

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0051082	unfolded protein binding
0.33	GO:0043565	sequence-specific DNA binding

0.33

GO:0005739

mitochondrion

0.34

GO:0032440

sp|Q9BJZ5|FUSIL_DROME
RNA-binding protein fusilli
Search

0.86	RNA-binding protein fusilli

0.62	GO:0007173	epidermal growth factor receptor signaling pathway
0.60	GO:0043484	regulation of RNA splicing
0.38	GO:0008380	RNA splicing
0.38	GO:0006397	mRNA processing

0.59

GO:0003723

RNA binding

0.36	GO:0005634	nucleus
0.34	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0044425	membrane part

tr|Q9BMG9|Q9BMG9_DROME
Beaten path IIa
Search

0.78	Beaten path IIa

0.56

GO:0007157

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

0.42

GO:0005515

protein binding

0.42

GO:0005887

integral component of plasma membrane

sp|Q9GN97|PGPLD_DROME
Peptidoglycan-recognition protein LD
Search

0.97	Peptidoglycan-recognition protein LD

0.74	GO:0009253	peptidoglycan catabolic process
0.44	GO:0045087	innate immune response

0.76	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.63	GO:0008270	zinc ion binding
0.44	GO:0042834	peptidoglycan binding

0.41

GO:0005887

integral component of plasma membrane

0.76

GO:0008745

sp|Q9GNK5|PGPLC_DROME
Peptidoglycan-recognition protein LC
Search

0.92	Peptidoglycan-recognition protein LC

0.74	GO:0009253	peptidoglycan catabolic process
0.56	GO:0061059	positive regulation of peptidoglycan recognition protein signaling pathway
0.55	GO:0035007	regulation of melanization defense response
0.54	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.54	GO:0061057	peptidoglycan recognition protein signaling pathway
0.53	GO:0006955	immune response
0.51	GO:0048167	regulation of synaptic plasticity
0.51	GO:0050829	defense response to Gram-negative bacterium
0.50	GO:0002221	pattern recognition receptor signaling pathway
0.48	GO:0051607	defense response to virus

0.76	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0042834	peptidoglycan binding
0.55	GO:0016019	peptidoglycan receptor activity
0.45	GO:0046983	protein dimerization activity
0.39	GO:0001875	lipopolysaccharide receptor activity

0.52	GO:0016327	apicolateral plasma membrane
0.49	GO:0098793	presynapse
0.44	GO:0005887	integral component of plasma membrane
0.40	GO:0089717	spanning component of membrane
0.37	GO:0005737	cytoplasm
0.34	GO:0005576	extracellular region

0.76

GO:0008745

sp|Q9GNL3|FEND_DROME
Transmembrane protein fend
Search

0.95	Transmembrane protein fend

0.66

GO:0008045

motor neuron axon guidance

0.30

GO:0044425

membrane part

sp|Q9GPJ1|SKEL2_DROME
Protein Skeletor, isoforms D/E
Search

0.63	Protein Skeletor, isoforms D/E

0.74	GO:0051225	spindle assembly
0.30	GO:0051321	meiotic cell cycle
0.30	GO:0006997	nucleus organization
0.30	GO:0051301	cell division

0.56

GO:0005198

structural molecule activity

0.76	GO:0005700	polytene chromosome
0.56	GO:0005634	nucleus
0.30	GO:0044422	organelle part
0.30	GO:0005737	cytoplasm
0.30	GO:0099081	supramolecular polymer
0.30	GO:0005856	cytoskeleton
0.30	GO:0044425	membrane part
0.30	GO:0031974	membrane-enclosed lumen

sp|Q9GQF1|JIP3_DROME
JNK-interacting protein 3
Search

0.95	JNK-interacting protein 3

0.84	GO:0008088	axo-dendritic transport
0.67	GO:0016192	vesicle-mediated transport
0.52	GO:0046328	regulation of JNK cascade
0.51	GO:0043410	positive regulation of MAPK cascade
0.48	GO:0007254	JNK cascade
0.47	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade
0.46	GO:0043405	regulation of MAP kinase activity
0.46	GO:0032147	activation of protein kinase activity
0.46	GO:0071902	positive regulation of protein serine/threonine kinase activity

0.84	GO:0019894	kinesin binding
0.55	GO:0005078	MAP-kinase scaffold activity
0.50	GO:0008432	JUN kinase binding
0.48	GO:0030159	receptor signaling complex scaffold activity
0.38	GO:0046982	protein heterodimerization activity
0.36	GO:0016301	kinase activity
0.35	GO:0003677	DNA binding

0.80	GO:0030140	trans-Golgi network transport vesicle
0.75	GO:0043005	neuron projection
0.47	GO:0000139	Golgi membrane
0.38	GO:0000786	nucleosome
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q9GQN0|RBP16_DROME
Ran-binding protein 16
Search

0.79	Ran-binding protein 16

0.68	GO:0006886	intracellular protein transport
0.46	GO:0006611	protein export from nucleus
0.37	GO:0051028	mRNA transport
0.34	GO:0007020	microtubule nucleation
0.34	GO:0006606	protein import into nucleus

0.79	GO:0008536	Ran GTPase binding
0.47	GO:0005049	nuclear export signal receptor activity
0.34	GO:0043015	gamma-tubulin binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005634	nucleus
0.41	GO:0012505	endomembrane system
0.39	GO:0031967	organelle envelope
0.39	GO:0043234	protein complex
0.36	GO:0005737	cytoplasm
0.34	GO:0000922	spindle pole
0.34	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

sp|Q9GQN5|ATRX_DROME
Transcriptional regulator ATRX homolog
Search

0.38	Transcriptional regulator ATRX

0.50	GO:0070868	heterochromatin organization involved in chromatin silencing
0.49	GO:0008347	glial cell migration
0.49	GO:0006336	DNA replication-independent nucleosome assembly
0.48	GO:0097193	intrinsic apoptotic signaling pathway
0.48	GO:0046328	regulation of JNK cascade
0.47	GO:0007411	axon guidance
0.35	GO:0006281	DNA repair

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016887	ATPase activity
0.37	GO:0004386	helicase activity
0.33	GO:0003677	DNA binding

0.53	GO:0005722	beta-heterochromatin
0.51	GO:0042585	germinal vesicle

0.41

GO:0016887

sp|Q9GQQ0|SPIN_DROME
Protein spinster
Search

0.38	Integral membrane efflux protein efpa

0.55	GO:0055085	transmembrane transport
0.39	GO:0008643	carbohydrate transport
0.38	GO:0003376	sphingosine-1-phosphate signaling pathway
0.37	GO:0035193	larval central nervous system remodeling
0.37	GO:0090099	negative regulation of decapentaplegic signaling pathway
0.37	GO:0045477	regulation of nurse cell apoptotic process
0.37	GO:0045476	nurse cell apoptotic process
0.37	GO:0045924	regulation of female receptivity
0.37	GO:0051124	synaptic growth at neuromuscular junction
0.37	GO:0007619	courtship behavior

0.38

GO:0046624

sphingolipid transporter activity

0.37	GO:0005765	lysosomal membrane
0.36	GO:0031902	late endosome membrane
0.35	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

tr|Q9GSR1|Q9GSR1_DROME
DNA polymerase zeta catalytic subunit
Search

0.30	DNA polymerase zeta catalytic subunit

0.84	GO:0019985	translesion synthesis
0.61	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0006260	DNA replication
0.54	GO:0000724	double-strand break repair via homologous recombination
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.70	GO:0008408	3'-5' exonuclease activity
0.55	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0003677	DNA binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.46	GO:0046872	metal ion binding
0.34	GO:0004871	signal transducer activity

0.85	GO:0016035	zeta DNA polymerase complex
0.52	GO:0005634	nucleus
0.36	GO:1905360	GTPase complex
0.36	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.34	GO:0098797	plasma membrane protein complex
0.33	GO:0043233	organelle lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.71

EC:2.7.7.7

GO:0003887

tr|Q9GU23|Q9GU23_DROME
Beta-galactoside alpha-2,6-sialyltransferase
Search

ST6GAL

0.45	Sialyltransferase

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0007528	neuromuscular junction development
0.53	GO:0009311	oligosaccharide metabolic process
0.35	GO:0006054	N-acetylneuraminate metabolic process
0.34	GO:2000110	negative regulation of macrophage apoptotic process
0.33	GO:0050922	negative regulation of chemotaxis

0.83	GO:0008373	sialyltransferase activity
0.31	GO:0050662	coenzyme binding
0.31	GO:0005515	protein binding

0.54	GO:0005794	Golgi apparatus
0.46	GO:0005576	extracellular region
0.41	GO:0098588	bounding membrane of organelle
0.41	GO:0031984	organelle subcompartment
0.33	GO:0031982	vesicle
0.32	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.99

GO:0008373

tr|Q9GU50|Q9GU50_DROME
GH09802p
Search

0.85	GO:0046579	positive regulation of Ras protein signal transduction
0.35	GO:0007165	signal transduction

0.35

GO:0005737

cytoplasm

tr|Q9GU54|Q9GU54_DROME
LD15753p
Search

0.13	Leucine-rich repeat-containing protein C10orf11

0.68	GO:0046579	positive regulation of Ras protein signal transduction
0.49	GO:0006270	DNA replication initiation

0.46	GO:0004386	helicase activity
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0003677	DNA binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008144	drug binding

0.51	GO:0042555	MCM complex
0.43	GO:0005634	nucleus

sp|Q9GU68|IF5A_DROME
Eukaryotic translation initiation factor 5A
Search

0.65	Eukaryotic translation initiation factor 5A

0.84	GO:0045905	positive regulation of translational termination
0.84	GO:0045901	positive regulation of translational elongation
0.83	GO:0006452	translational frameshifting
0.62	GO:0006413	translational initiation
0.44	GO:0032504	multicellular organism reproduction
0.42	GO:0042981	regulation of apoptotic process
0.36	GO:0019953	sexual reproduction
0.36	GO:0035262	gonad morphogenesis
0.36	GO:0045138	nematode male tail tip morphogenesis
0.35	GO:0002119	nematode larval development

0.74	GO:0043022	ribosome binding
0.70	GO:0003746	translation elongation factor activity
0.63	GO:0003743	translation initiation factor activity
0.32	GO:0005515	protein binding

0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9GYU7|MED10_DROME
Mediator of RNA polymerase II transcription subunit 10
Search

MED10

0.94	Mediator of RNA polymerase II transcription subunit 10

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.46	GO:0007406	negative regulation of neuroblast proliferation
0.45	GO:0019827	stem cell population maintenance
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:1905072	cardiac jelly development
0.39	GO:0036302	atrioventricular canal development
0.34	GO:0016567	protein ubiquitination
0.33	GO:0006508	proteolysis
0.32	GO:0005975	carbohydrate metabolic process

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0004563	beta-N-acetylhexosaminidase activity
0.34	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.77	GO:0016592	mediator complex
0.46	GO:0070847	core mediator complex
0.34	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

0.34

EC:3.2.1.52

GO:0004563

sp|Q9GYU8|NUP88_DROME
Nuclear pore complex protein Nup88
Search

0.61	Nuclear pore complex protein Nup88

0.85	GO:0000056	ribosomal small subunit export from nucleus
0.84	GO:0000055	ribosomal large subunit export from nucleus
0.73	GO:0046826	negative regulation of protein export from nucleus
0.72	GO:0006913	nucleocytoplasmic transport
0.69	GO:0019730	antimicrobial humoral response
0.62	GO:0017038	protein import
0.60	GO:0072594	establishment of protein localization to organelle
0.44	GO:0035147	branch fusion, open tracheal system
0.42	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.41	GO:0051028	mRNA transport

0.80	GO:0017056	structural constituent of nuclear pore
0.63	GO:0003682	chromatin binding
0.38	GO:0005515	protein binding
0.36	GO:0005215	transporter activity
0.34	GO:0009881	photoreceptor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0003676	nucleic acid binding

0.63	GO:0005643	nuclear pore
0.59	GO:0000785	chromatin
0.58	GO:0005654	nucleoplasm
0.41	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

sp|Q9GYV5|NEMO_DROME
NF-kappa-B essential modulator
Search

KEY

0.90	NF-kappa-B essential modulator

0.50	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.50	GO:0061057	peptidoglycan recognition protein signaling pathway
0.49	GO:2000647	negative regulation of stem cell proliferation
0.49	GO:0002230	positive regulation of defense response to virus by host
0.49	GO:0008063	Toll signaling pathway
0.47	GO:0050829	defense response to Gram-negative bacterium
0.47	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.47	GO:0045089	positive regulation of innate immune response
0.46	GO:0045087	innate immune response
0.46	GO:0051607	defense response to virus

0.85	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.38	GO:0046872	metal ion binding
0.35	GO:0003676	nucleic acid binding

0.43	GO:0005829	cytosol
0.40	GO:0005634	nucleus

sp|Q9GYV9|MED7_DROME
Mediator of RNA polymerase II transcription subunit 7
Search

0.70	Mediator of RNA polymerase II transcription subunit 7

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.41	GO:0019827	stem cell population maintenance

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.37	GO:0003713	transcription coactivator activity
0.33	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.42	GO:0005667	transcription factor complex
0.40	GO:0016604	nuclear body
0.38	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.30	GO:0031224	intrinsic component of membrane

tr|Q9I7C6|Q9I7C6_DROME
Cuticular protein 65Ax1
Search

0.94	Larval cuticle protein 5

0.42	GO:0040003	chitin-based cuticle development
0.37	GO:0002168	instar larval development
0.37	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.39	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

tr|Q9I7D0|Q9I7D0_DROME
GH22314p
Search

0.76	Phosphorylase kinase gamma

0.72	GO:0005978	glycogen biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.52	GO:0048598	embryonic morphogenesis
0.43	GO:0006007	glucose catabolic process
0.40	GO:0018210	peptidyl-threonine modification
0.40	GO:0018209	peptidyl-serine modification
0.38	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.37	GO:0006289	nucleotide-excision repair
0.36	GO:0035556	intracellular signal transduction

0.83	GO:0004689	phosphorylase kinase activity
0.74	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003684	damaged DNA binding
0.36	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity

0.82	GO:0005964	phosphorylase kinase complex
0.36	GO:0005634	nucleus
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0005667	transcription factor complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.7.11.19

GO:0004689

sp|Q9I7D3|CAPR1_DROME
Caprin homolog
Search

0.92	caprin homolog

0.85	GO:0045571	negative regulation of imaginal disc growth
0.84	GO:0009794	regulation of mitotic cell cycle, embryonic
0.81	GO:0007349	cellularization
0.38	GO:0045498	sex comb development
0.38	GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death
0.37	GO:0036011	imaginal disc-derived leg segmentation
0.37	GO:0007406	negative regulation of neuroblast proliferation
0.37	GO:0022416	chaeta development
0.37	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.37	GO:0048749	compound eye development

0.57	GO:0003723	RNA binding
0.38	GO:0005509	calcium ion binding
0.37	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0017111	nucleoside-triphosphatase activity
0.36	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.36	GO:0050825	ice binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008144	drug binding

0.58	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0005737	cytoplasm
0.37	GO:0070847	core mediator complex
0.37	GO:0005700	polytene chromosome
0.37	GO:0016592	mediator complex
0.34	GO:0099023	tethering complex
0.34	GO:0031312	extrinsic component of organelle membrane
0.33	GO:0071944	cell periphery
0.33	GO:0005730	nucleolus
0.33	GO:0019013	viral nucleocapsid

0.36

EC:3.6.1.15

GO:0017111

sp|Q9I7F7|PR2_DROME
Tyrosine-protein kinase PR2
Search

0.59	Tyrosine-protein kinase PR2

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.42	GO:0046777	protein autophosphorylation
0.42	GO:0045087	innate immune response
0.41	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.41	GO:0016477	cell migration
0.41	GO:0042127	regulation of cell proliferation
0.40	GO:0030154	cell differentiation

0.76	GO:0004713	protein tyrosine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005102	receptor binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding

0.42

GO:0031234

extrinsic component of cytoplasmic side of plasma membrane

0.76

EC:2.7.10

GO:0004713

tr|Q9I7H4|Q9I7H4_DROME
CG9717
Search

S2611

0.42	sodium-independent sulfate anion transporter

0.75	GO:1902358	sulfate transmembrane transport
0.44	GO:0045434	negative regulation of female receptivity, post-mating
0.40	GO:0015701	bicarbonate transport
0.40	GO:0019532	oxalate transport
0.40	GO:0051453	regulation of intracellular pH
0.39	GO:0042391	regulation of membrane potential
0.38	GO:1902476	chloride transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.78	GO:0008271	secondary active sulfate transmembrane transporter activity
0.40	GO:0015106	bicarbonate transmembrane transporter activity
0.40	GO:0019531	oxalate transmembrane transporter activity
0.40	GO:0015301	anion:anion antiporter activity
0.39	GO:0005254	chloride channel activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.37

GO:0005887

integral component of plasma membrane

0.33

GO:0016705

tr|Q9I7H5|Q9I7H5_DROME
Prolyl 4-hydroxylase alpha-related protein PH4[alpha]SG2
Search

0.44	prolyl 4-hydroxylase subunit alpha-1

0.83	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0007435	salivary gland morphogenesis
0.53	GO:0055114	oxidation-reduction process
0.39	GO:0019471	4-hydroxyproline metabolic process
0.38	GO:0030199	collagen fibril organization
0.35	GO:0051321	meiotic cell cycle
0.33	GO:0050482	arachidonic acid secretion
0.33	GO:0016042	lipid catabolic process
0.32	GO:0006644	phospholipid metabolic process
0.32	GO:0006091	generation of precursor metabolites and energy

0.84	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.73	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.63	GO:0005506	iron ion binding
0.37	GO:0042802	identical protein binding
0.33	GO:0016787	hydrolase activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0009055	electron transfer activity

0.70	GO:0005783	endoplasmic reticulum
0.37	GO:0043233	organelle lumen
0.37	GO:0005829	cytosol
0.36	GO:0044446	intracellular organelle part
0.36	GO:1990204	oxidoreductase complex
0.35	GO:0005634	nucleus
0.35	GO:0005739	mitochondrion
0.32	GO:0005581	collagen trimer
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.84	EC:1.14.11.2	GO:0004656
0.84	KEGG:R03219	GO:0004656

tr|Q9I7H8|Q9I7H8_DROME
LD37276p
Search

0.12	Transcription factor Gt-2

0.55

GO:0003677

DNA binding

sp|Q9I7H9|OGFD1_DROME
Prolyl 3-hydroxylase sudestada1
Search

0.80	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1

0.59	GO:0016255	attachment of GPI anchor to protein
0.55	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006417	regulation of translation
0.39	GO:0043244	regulation of protein complex disassembly
0.38	GO:0016310	phosphorylation
0.34	GO:0045313	rhabdomere membrane biogenesis

0.80	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.79	GO:0031418	L-ascorbic acid binding
0.63	GO:0005506	iron ion binding
0.43	GO:0003951	NAD+ kinase activity
0.43	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0042578	phosphoric ester hydrolase activity

0.58	GO:0042765	GPI-anchor transamidase complex
0.44	GO:0005634	nucleus
0.32	GO:0070013	intracellular organelle lumen

0.80	EC:1.14.11	GO:0016706
0.43	KEGG:R00104	GO:0003951

sp|Q9I7I0|CCNB3_DROME
G2/mitotic-specific cyclin-B3
Search

0.84	G2/mitotic-specific cyclin-B3

0.82	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.81	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.53	GO:0035186	syncytial blastoderm mitotic cell cycle
0.52	GO:0035561	regulation of chromatin binding
0.49	GO:0000281	mitotic cytokinesis
0.33	GO:0006397	mRNA processing

0.78

GO:0019901

protein kinase binding

0.61	GO:0005634	nucleus
0.32	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|Q9I7I1|Q9I7I1_DROME
Uncharacterized protein, isoform B
Search

0.59	venom protease

0.61	GO:0006508	proteolysis
0.43	GO:0035008	positive regulation of melanization defense response
0.41	GO:0035006	melanization defense response
0.35	GO:0007596	blood coagulation
0.34	GO:0006956	complement activation
0.33	GO:0010466	negative regulation of peptidase activity
0.33	GO:0006281	DNA repair
0.33	GO:0006898	receptor-mediated endocytosis
0.32	GO:0055114	oxidation-reduction process

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0030414	peptidase inhibitor activity

0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.69

GO:0004252

tr|Q9I7I3|Q9I7I3_DROME
GH12831p
Search

0.14	vitamin K-dependent protein C

0.61

GO:0006508

proteolysis

0.69

GO:0004252

serine-type endopeptidase activity

0.69

GO:0004252

tr|Q9I7I6|Q9I7I6_DROME
CG5191, isoform B
Search

0.33	Fatty-acid amide hydrolase 2

0.37	GO:0034227	tRNA thio-modification
0.36	GO:0032447	protein urmylation
0.36	GO:0002098	tRNA wobble uridine modification
0.34	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0007165	signal transduction
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0006468	protein phosphorylation
0.32	GO:0009059	macromolecule biosynthetic process

0.50	GO:0016874	ligase activity
0.47	GO:0004040	amidase activity
0.35	GO:0000049	tRNA binding
0.34	GO:0016779	nucleotidyltransferase activity
0.34	GO:0000213	tRNA-intron endonuclease activity
0.32	GO:0004707	MAP kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005634	nucleus
0.33	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.50	EC:6	GO:0016874
0.32	KEGG:R00162	GO:0004707

sp|Q9I7I7|SIRT2_DROME
NAD-dependent protein deacetylase Sirt2
Search

SIRT2

0.59	NAD-dependent protein deacetylase

0.77	GO:0016575	histone deacetylation
0.49	GO:0034983	peptidyl-lysine deacetylation
0.47	GO:0008340	determination of adult lifespan
0.46	GO:0061433	cellular response to caloric restriction
0.46	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
0.46	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly
0.46	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.46	GO:0090042	tubulin deacetylation
0.46	GO:1900195	positive regulation of oocyte maturation
0.45	GO:0071872	cellular response to epinephrine stimulus

0.78	GO:0017136	NAD-dependent histone deacetylase activity
0.77	GO:0070403	NAD+ binding
0.61	GO:0008270	zinc ion binding
0.46	GO:0042903	tubulin deacetylase activity
0.45	GO:0034739	histone deacetylase activity (H4-K16 specific)
0.45	GO:0035035	histone acetyltransferase binding
0.44	GO:0042826	histone deacetylase binding
0.43	GO:0043130	ubiquitin binding
0.42	GO:0003682	chromatin binding
0.41	GO:0008134	transcription factor binding

0.46	GO:0033010	paranodal junction
0.45	GO:0043220	Schmidt-Lanterman incisure
0.44	GO:0072687	meiotic spindle
0.44	GO:0043204	perikaryon
0.43	GO:0030496	midbody
0.43	GO:0005814	centriole
0.43	GO:0072686	mitotic spindle
0.42	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005813	centrosome
0.41	GO:0005874	microtubule

0.34

EC:2.4.2.30

GO:0003950

tr|Q9I7J0|Q9I7J0_DROME
CG5023
Search

0.77	Calponin/transgelin

0.74	GO:0031032	actomyosin structure organization
0.34	GO:0043535	regulation of blood vessel endothelial cell migration
0.34	GO:0051764	actin crosslink formation
0.34	GO:0043408	regulation of MAPK cascade
0.33	GO:0000281	mitotic cytokinesis
0.33	GO:0006298	mismatch repair
0.33	GO:0001300	chronological cell aging
0.32	GO:0006468	protein phosphorylation
0.32	GO:0005975	carbohydrate metabolic process

0.67	GO:0003779	actin binding
0.60	GO:0005516	calmodulin binding
0.34	GO:0008017	microtubule binding
0.34	GO:0032403	protein complex binding
0.33	GO:0030983	mismatched DNA binding
0.33	GO:0030674	protein binding, bridging
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004672	protein kinase activity

0.34	GO:0005856	cytoskeleton
0.34	GO:0061645	endocytic patch
0.33	GO:0032300	mismatch repair complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0004553

tr|Q9I7J1|Q9I7J1_DROME
CG4733, isoform B
Search

0.54	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

0.42	GO:0090249	regulation of cell motility involved in somitogenic axis elongation
0.41	GO:0007525	somatic muscle development
0.40	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.40	GO:0001754	eye photoreceptor cell differentiation
0.40	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.39	GO:0045732	positive regulation of protein catabolic process
0.35	GO:0090244	Wnt signaling pathway involved in somitogenesis
0.34	GO:0006470	protein dephosphorylation
0.34	GO:0043666	regulation of phosphoprotein phosphatase activity

0.70	GO:0005509	calcium ion binding
0.39	GO:0030674	protein binding, bridging
0.34	GO:0019888	protein phosphatase regulator activity
0.33	GO:0004721	phosphoprotein phosphatase activity

0.45

GO:0000159

protein phosphatase type 2A complex

0.33

GO:0004721

tr|Q9I7J2|Q9I7J2_DROME
FI19351p1
Search

0.42	Sex-determining protein fem-1

0.67	GO:0016567	protein ubiquitination
0.38	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0007165	signal transduction
0.34	GO:0009116	nucleoside metabolic process

0.68	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0004867	serine-type endopeptidase inhibitor activity

0.30

GO:0031224

intrinsic component of membrane

0.68

GO:0004842

tr|Q9I7J8|Q9I7J8_DROME
FI01424p
Search

0.10	transcription factor Ouib

0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0006366	transcription by RNA polymerase II
0.40	GO:0045998	positive regulation of ecdysteroid biosynthetic process
0.39	GO:0002168	instar larval development
0.37	GO:0022412	cellular process involved in reproduction in multicellular organism
0.37	GO:0007276	gamete generation
0.36	GO:0002066	columnar/cuboidal epithelial cell development

0.51	GO:0003676	nucleic acid binding
0.48	GO:0008270	zinc ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding

0.49	GO:0005634	nucleus
0.38	GO:0043233	organelle lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9I7K0|JUPIT_DROME
Microtubule-associated protein Jupiter
Search

0.94	Microtubule-associated protein Jupiter

0.85	GO:0031116	positive regulation of microtubule polymerization
0.71	GO:0007010	cytoskeleton organization

0.77	GO:0005200	structural constituent of cytoskeleton
0.74	GO:0008017	microtubule binding

0.76	GO:0005875	microtubule associated complex
0.74	GO:0005819	spindle
0.71	GO:0005874	microtubule
0.68	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.34	GO:0012505	endomembrane system
0.34	GO:0043233	organelle lumen
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane

tr|Q9I7K3|Q9I7K3_DROME
Aminoacylase
Search

0.49	N-acyl-L-amino-acid amidohydrolase

0.59	GO:0006520	cellular amino acid metabolic process
0.54	GO:0006508	proteolysis

0.85	GO:0004046	aminoacylase activity
0.59	GO:0008237	metallopeptidase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.49	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus

0.85

EC:3.5.1.14

GO:0004046

tr|Q9I7K4|Q9I7K4_DROME
LD18367p
Search

0.40	Acetyltransferase YpeA

0.58

GO:0008080

N-acetyltransferase activity

0.30

GO:0044425

membrane part

0.58

GO:0008080

sp|Q9I7K5|TMEDE_DROME
Transmembrane emp24 domain-containing protein eca
Search

ECA

0.42	Transmembrane emp24 domain-containing protein eca

0.45	GO:0009953	dorsal/ventral pattern formation
0.38	GO:0048042	regulation of post-mating oviposition
0.36	GO:0048193	Golgi vesicle transport
0.36	GO:0061355	Wnt protein secretion
0.35	GO:0034389	lipid particle organization
0.35	GO:0035220	wing disc development
0.35	GO:0007030	Golgi organization
0.34	GO:0046907	intracellular transport

0.35	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0005215	transporter activity

0.67	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016757

sp|Q9I7K6|NASP_DROME
Protein NASP homolog
Search

0.11	Tetratricopeptide repeat protein

0.45	GO:0042176	regulation of protein catabolic process
0.45	GO:0006413	translational initiation
0.44	GO:0000056	ribosomal small subunit export from nucleus
0.44	GO:0016973	poly(A)+ mRNA export from nucleus
0.44	GO:0000055	ribosomal large subunit export from nucleus
0.42	GO:0050790	regulation of catalytic activity
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.45	GO:0003743	translation initiation factor activity
0.43	GO:0005487	structural constituent of nuclear pore
0.43	GO:0030234	enzyme regulator activity
0.36	GO:0003700	DNA binding transcription factor activity

0.57	GO:0005634	nucleus
0.47	GO:0005852	eukaryotic translation initiation factor 3 complex
0.44	GO:1905369	endopeptidase complex
0.40	GO:0012505	endomembrane system
0.38	GO:0031967	organelle envelope

tr|Q9I7K7|Q9I7K7_DROME
Uncharacterized protein
Search

0.13	arrestin domain-containing protein 5

0.61

GO:0007165

signal transduction

tr|Q9I7K8|Q9I7K8_DROME
FI07222p
Search

0.57	arrestin domain-containing protein 3

0.61

GO:0007165

signal transduction

tr|Q9I7L0|Q9I7L0_DROME
LP01847p
Search

0.64	arrestin domain-containing protein 3

0.61	GO:0007165	signal transduction
0.34	GO:0006303	double-strand break repair via nonhomologous end joining

0.32

GO:0003677

DNA binding

tr|Q9I7L1|Q9I7L1_DROME
Uncharacterized protein
Search

0.63	arrestin domain-containing protein 3

0.61	GO:0007165	signal transduction
0.33	GO:0006303	double-strand break repair via nonhomologous end joining

0.32

GO:0003677

DNA binding

tr|Q9I7L3|Q9I7L3_DROME
Uncharacterized protein
Search

0.53	Phosphatidylethanolamine-binding protein transcript variant X1

0.69	GO:0002759	regulation of antimicrobial humoral response
0.67	GO:0050830	defense response to Gram-positive bacterium
0.66	GO:0050829	defense response to Gram-negative bacterium

0.38

GO:0005840

ribosome

tr|Q9I7L4|Q9I7L4_DROME
MAGE
Search

MAGE

0.88	melanoma-associated antigen B16

0.86	GO:0031000	response to caffeine
0.86	GO:0007406	negative regulation of neuroblast proliferation
0.84	GO:0043524	negative regulation of neuron apoptotic process
0.64	GO:0006974	cellular response to DNA damage stimulus
0.54	GO:0016925	protein sumoylation
0.44	GO:0006259	DNA metabolic process

0.55	GO:0019789	SUMO transferase activity
0.41	GO:0005515	protein binding

0.54	GO:0030915	Smc5-Smc6 complex
0.45	GO:0005634	nucleus

tr|Q9I7L6|Q9I7L6_DROME
Torn and diminished rhabdomeres, isoform D
Search

0.56	Torn and diminished rhabdomeres, isoform D

0.41	GO:1902475	L-alpha-amino acid transmembrane transport
0.40	GO:1990822	basic amino acid transmembrane transport

0.41	GO:0015179	L-amino acid transmembrane transporter activity
0.40	GO:0015174	basic amino acid transmembrane transporter activity
0.39	GO:0015297	antiporter activity

0.38

GO:0005887

integral component of plasma membrane

tr|Q9I7L7|Q9I7L7_DROME
Palmitoyltransferase
Search

0.30	Palmitoyltransferase

0.52	GO:0018345	protein palmitoylation
0.48	GO:0072659	protein localization to plasma membrane
0.33	GO:0048193	Golgi vesicle transport

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.32	GO:0005515	protein binding

0.53	GO:0012505	endomembrane system
0.46	GO:0043231	intracellular membrane-bounded organelle
0.45	GO:0044444	cytoplasmic part
0.39	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.3.1.225

GO:0019706

tr|Q9I7L8|Q9I7L8_DROME
Cell division cycle 23 ortholog, isoform A
Search

CDC23

0.78	Anaphase-promoting complex subunit 8

0.79	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.54	GO:0051301	cell division
0.51	GO:0070979	protein K11-linked ubiquitination
0.50	GO:0007080	mitotic metaphase plate congression
0.37	GO:0007113	endomitotic cell cycle
0.36	GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle
0.36	GO:1901970	positive regulation of mitotic sister chromatid separation
0.36	GO:1901992	positive regulation of mitotic cell cycle phase transition
0.35	GO:0016579	protein deubiquitination
0.35	GO:0090175	regulation of establishment of planar polarity

0.36	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.79	GO:0005680	anaphase-promoting complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.35	EC:3.4.19.12	GO:0036459
0.36	KEGG:R03876	GO:0004842

tr|Q9I7L9|Q9I7L9_DROME
Uncharacterized protein, isoform A
Search

0.65	Phosphatidylcholine-sterol acyltransferase

0.63	GO:0006629	lipid metabolic process
0.32	GO:0006468	protein phosphorylation

0.74	GO:0008374	O-acyltransferase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

0.74

GO:0008374

tr|Q9I7M1|Q9I7M1_DROME
Olfactory-specific 9
Search

OS9

0.93	Olfactory-specific 9

0.72

GO:0007608

sensory perception of smell

0.61

GO:0005634

nucleus

sp|Q9I7M2|GTPBA_DROME
GTP-binding protein 10 homolog
Search

0.71	GTP-binding protein 10

0.39

GO:0042254

ribosome biogenesis

0.66	GO:0001883	purine nucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003924	GTPase activity
0.36	GO:0000287	magnesium ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding
0.32	GO:0030554	adenyl nucleotide binding

0.39	GO:0005739	mitochondrion
0.38	GO:0005730	nucleolus
0.33	GO:0005694	chromosome

tr|Q9I7M5|Q9I7M5_DROME
Uncharacterized protein
Search

0.83	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.80	GO:0030071	regulation of mitotic metaphase/anaphase transition

0.80

GO:0005680

anaphase-promoting complex

tr|Q9I7M8|Q9I7M8_DROME
ATP-dependent DNA helicase II subunit 2
Search

0.68	ATP-dependent DNA helicase II subunit 2

0.81	GO:0006303	double-strand break repair via nonhomologous end joining
0.79	GO:0000723	telomere maintenance
0.72	GO:0071480	cellular response to gamma radiation
0.72	GO:0045471	response to ethanol
0.65	GO:0006310	DNA recombination

0.82	GO:0042162	telomeric DNA binding
0.73	GO:0003684	damaged DNA binding
0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0043564	Ku70:Ku80 complex
0.43	GO:0000784	nuclear chromosome, telomeric region

tr|Q9I7N1|Q9I7N1_DROME
Uncharacterized protein
Search

0.10	putative inorganic phosphate cotransporter

0.55	GO:0055085	transmembrane transport
0.45	GO:0051938	L-glutamate import
0.42	GO:0044341	sodium-dependent phosphate transport
0.41	GO:0007005	mitochondrion organization
0.40	GO:0006541	glutamine metabolic process
0.35	GO:0048190	wing disc dorsal/ventral pattern formation
0.35	GO:0001666	response to hypoxia
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.45	GO:0005314	high-affinity glutamate transmembrane transporter activity
0.42	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.36	GO:0015319	sodium:inorganic phosphate symporter activity
0.33	GO:0004930	G-protein coupled receptor activity

0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q9I7N2|Q9I7N2_DROME
Uncharacterized protein
Search

AMO1

0.73	mastermind-like protein 2

0.39	GO:0090114	COPII-coated vesicle budding
0.38	GO:0015031	protein transport
0.38	GO:0070727	cellular macromolecule localization
0.38	GO:0043547	positive regulation of GTPase activity
0.37	GO:0050789	regulation of biological process
0.36	GO:0019538	protein metabolic process
0.36	GO:0043412	macromolecule modification
0.36	GO:0016310	phosphorylation
0.35	GO:0023052	signaling
0.35	GO:0007154	cell communication

0.51	GO:0046872	metal ion binding
0.39	GO:0003712	transcription cofactor activity
0.38	GO:0005096	GTPase activator activity
0.37	GO:0017137	Rab GTPase binding
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0016301	kinase activity
0.36	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0003676	nucleic acid binding
0.35	GO:0050825	ice binding
0.35	GO:0004402	histone acetyltransferase activity

0.39	GO:0030127	COPII vesicle coat
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0031248	protein acetyltransferase complex
0.37	GO:0031984	organelle subcompartment
0.37	GO:1905368	peptidase complex
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0008021	synaptic vesicle

0.36	EC:2.7.1	GO:0016773
0.35	KEGG:R03165	GO:0004852

tr|Q9I7N3|Q9I7N3_DROME
Uncharacterized protein
Search

AMO1

0.73	mastermind-like protein 2

0.40	GO:0090114	COPII-coated vesicle budding
0.39	GO:0015031	protein transport
0.38	GO:0070727	cellular macromolecule localization
0.37	GO:0043547	positive regulation of GTPase activity
0.37	GO:0036211	protein modification process
0.37	GO:0016569	covalent chromatin modification
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0050789	regulation of biological process
0.36	GO:0023052	signaling
0.36	GO:0007154	cell communication

0.51	GO:0046872	metal ion binding
0.38	GO:0005096	GTPase activator activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0017137	Rab GTPase binding
0.36	GO:0016278	lysine N-methyltransferase activity
0.36	GO:0016301	kinase activity
0.36	GO:0003712	transcription cofactor activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0003676	nucleic acid binding
0.35	GO:0004402	histone acetyltransferase activity

0.39	GO:0030127	COPII vesicle coat
0.38	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0031984	organelle subcompartment
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:1990234	transferase complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0097458	neuron part
0.34	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0005839	proteasome core complex
0.34	GO:0030529	intracellular ribonucleoprotein complex

0.36	EC:2.1.1	GO:0016278
0.35	KEGG:R03165	GO:0004852

tr|Q9I7N9|Q9I7N9_DROME
FI18149p1
Search

SC6A9

0.48	Sodium-and chloride-dependent glycine transporter 1

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0015844	monoamine transport
0.50	GO:0090067	regulation of thalamus size
0.48	GO:0015850	organic hydroxy compound transport
0.47	GO:0015696	ammonium transport
0.45	GO:0046621	negative regulation of organ growth
0.45	GO:0035176	social behavior
0.45	GO:0048854	brain morphogenesis
0.43	GO:0045787	positive regulation of cell cycle

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.53	GO:0015222	serotonin transmembrane transporter activity
0.46	GO:0050998	nitric-oxide synthase binding
0.44	GO:0017137	Rab GTPase binding
0.42	GO:0005329	dopamine transmembrane transporter activity
0.37	GO:0019811	cocaine binding
0.36	GO:0017075	syntaxin-1 binding
0.36	GO:0051015	actin filament binding
0.36	GO:0017022	myosin binding
0.35	GO:0042803	protein homodimerization activity

0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0098857	membrane microdomain
0.43	GO:0098793	presynapse
0.40	GO:0120025	plasma membrane bounded cell projection
0.40	GO:0005829	cytosol
0.40	GO:0012505	endomembrane system
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0098588	bounding membrane of organelle

tr|Q9I7P2|Q9I7P2_DROME
AT24795p
Search

tr|Q9I7P3|Q9I7P3_DROME
CG1126
Search

BBS5

0.91	Bardet-Biedl syndrome 5 protein homolog

0.54	GO:0060271	cilium assembly
0.46	GO:0072116	pronephros formation
0.45	GO:0051877	pigment granule aggregation in cell center
0.44	GO:0070121	Kupffer's vesicle development
0.43	GO:0032402	melanosome transport
0.43	GO:0001947	heart looping
0.42	GO:0048749	compound eye development
0.42	GO:0007369	gastrulation
0.37	GO:0006368	transcription elongation from RNA polymerase II promoter
0.37	GO:0035914	skeletal muscle cell differentiation

0.48	GO:0032266	phosphatidylinositol-3-phosphate binding
0.43	GO:0001103	RNA polymerase II repressing transcription factor binding
0.35	GO:0015129	lactate transmembrane transporter activity
0.33	GO:0005216	ion channel activity

0.84	GO:0034464	BBSome
0.48	GO:0036064	ciliary basal body
0.43	GO:0005930	axoneme
0.37	GO:0016593	Cdc73/Paf1 complex
0.36	GO:0060170	ciliary membrane
0.36	GO:0031430	M band
0.36	GO:0033017	sarcoplasmic reticulum membrane
0.35	GO:0031463	Cul3-RING ubiquitin ligase complex
0.34	GO:0005829	cytosol
0.34	GO:0005887	integral component of plasma membrane

tr|Q9I7P6|Q9I7P6_DROME
Globin 3
Search

0.86

Globin 3

0.77	GO:0015671	oxygen transport
0.38	GO:0055085	transmembrane transport

0.77	GO:0005344	oxygen carrier activity
0.63	GO:0020037	heme binding
0.56	GO:0019825	oxygen binding
0.38	GO:0022857	transmembrane transporter activity

0.40	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|Q9I7Q5|Q9I7Q5_DROME
Cuticular protein 65Au, isoform A
Search

0.72	Endocuticle structural glycoprotein SgAbd-5

0.42	GO:0040003	chitin-based cuticle development
0.35	GO:0002168	instar larval development
0.35	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.39	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

tr|Q9I7Q6|Q9I7Q6_DROME
FI01403p
Search

0.90	Larval cuticle protein 8

0.43	GO:0040003	chitin-based cuticle development
0.37	GO:0002168	instar larval development
0.37	GO:0007591	molting cycle, chitin-based cuticle
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.79	GO:0042302	structural constituent of cuticle
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0003676	nucleic acid binding

0.40	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.33

EC:3.1.26.4

GO:0004523

tr|Q9I7Q9|Q9I7Q9_DROME
Ribosomal protein
Search

0.51	Ribosomal protein (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005840	ribosome
0.41	GO:0005759	mitochondrial matrix
0.39	GO:0016604	nuclear body
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

tr|Q9I7R3|Q9I7R3_DROME
Alcohol dehydrogenase
Search

0.25	Short chain dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.47	GO:0006066	alcohol metabolic process
0.34	GO:0006633	fatty acid biosynthetic process

0.71	GO:0004022	alcohol dehydrogenase (NAD) activity
0.37	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.37	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.37	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.34	GO:0051287	NAD binding
0.33	GO:0055041	cyclopentanol dehydrogenase activity
0.33	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity
0.33	GO:0050574	2-(R)-hydroxypropyl-CoM dehydrogenase activity
0.32	GO:0031177	phosphopantetheine binding

0.30

GO:0031224

intrinsic component of membrane

0.71	EC:1.1.1.1	GO:0004022
0.33	KEGG:R02553	GO:0055041

tr|Q9I7R5|Q9I7R5_DROME
Uncharacterized protein, isoform A
Search

0.46	Importin beta-4

0.68	GO:0006886	intracellular protein transport
0.43	GO:0006610	ribosomal protein import into nucleus
0.43	GO:0006607	NLS-bearing protein import into nucleus
0.38	GO:0043248	proteasome assembly
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.79	GO:0008536	Ran GTPase binding
0.43	GO:0008139	nuclear localization sequence binding
0.39	GO:0008565	protein transporter activity
0.34	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.55	GO:0005634	nucleus
0.38	GO:0012505	endomembrane system
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q9I7R7|Q9I7R7_DROME
GH15549p
Search

LOC108097541

0.69	arginine/serine-rich coiled-coil protein 2 isoform X1

0.63	GO:0008340	determination of adult lifespan
0.46	GO:0006397	mRNA processing
0.40	GO:0008380	RNA splicing
0.37	GO:0006325	chromatin organization
0.36	GO:0006464	cellular protein modification process
0.35	GO:0006368	transcription elongation from RNA polymerase II promoter
0.35	GO:0031098	stress-activated protein kinase signaling cascade
0.35	GO:0007219	Notch signaling pathway
0.35	GO:0060255	regulation of macromolecule metabolic process
0.35	GO:0010501	RNA secondary structure unwinding

0.44	GO:0003723	RNA binding
0.39	GO:0008270	zinc ion binding
0.36	GO:0016972	thiol oxidase activity
0.36	GO:0043168	anion binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0003682	chromatin binding
0.35	GO:0008289	lipid binding
0.35	GO:0004386	helicase activity
0.34	GO:0140096	catalytic activity, acting on a protein

0.43	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0044444	cytoplasmic part
0.35	GO:0043233	organelle lumen
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0044446	intracellular organelle part
0.33	GO:0043234	protein complex
0.33	GO:0019867	outer membrane
0.33	GO:0043232	intracellular non-membrane-bounded organelle

0.36

EC:1.8.3.2

GO:0016972

tr|Q9I7S2|Q9I7S2_DROME
RH22417p
Search

0.43	Pyrimidine-specific ribonucleoside hydrolase RihA

0.47	GO:0009164	nucleoside catabolic process
0.46	GO:0072523	purine-containing compound catabolic process
0.44	GO:0042278	purine nucleoside metabolic process
0.38	GO:0046108	uridine metabolic process
0.38	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.37	GO:0019358	nicotinate nucleotide salvage
0.37	GO:0046087	cytidine metabolic process
0.36	GO:0072529	pyrimidine-containing compound catabolic process
0.36	GO:0008655	pyrimidine-containing compound salvage
0.33	GO:0055085	transmembrane transport

0.51	GO:0016787	hydrolase activity
0.34	GO:0022857	transmembrane transporter activity

0.43	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.51

GO:0016787

tr|Q9I7S5|Q9I7S5_DROME
CG2209
Search

sp|Q9I7S6|PDE9A_DROME
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Search

0.34	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.46	GO:0046069	cGMP catabolic process
0.39	GO:0014742	positive regulation of muscle hypertrophy
0.39	GO:0010611	regulation of cardiac muscle hypertrophy
0.39	GO:0035041	sperm chromatin decondensation
0.38	GO:0007143	female meiotic nuclear division
0.37	GO:1902275	regulation of chromatin organization
0.36	GO:0006357	regulation of transcription by RNA polymerase II

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.52	GO:0046872	metal ion binding
0.37	GO:0003682	chromatin binding
0.35	GO:0043565	sequence-specific DNA binding
0.33	GO:0042802	identical protein binding

0.38	GO:0042383	sarcolemma
0.36	GO:0000228	nuclear chromosome
0.34	GO:0043204	perikaryon
0.34	GO:0032587	ruffle membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.1.4.17

GO:0004114

sp|Q9I7S8|PUR6_DROME
Multifunctional protein ADE2
Search

0.62	Phosphoribosylamidoimidazole-succinocarboxamide synthase

0.70	GO:0006189	'de novo' IMP biosynthetic process
0.37	GO:0043473	pigmentation
0.37	GO:0060041	retina development in camera-type eye
0.37	GO:0043009	chordate embryonic development
0.32	GO:0016310	phosphorylation

0.78	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
0.39	GO:0004638	phosphoribosylaminoimidazole carboxylase activity
0.34	GO:0045296	cadherin binding
0.33	GO:0042802	identical protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016301	kinase activity

0.34	GO:0042721	mitochondrial inner membrane protein insertion complex
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.78	EC:6.3.2.6	GO:0004639
0.78	KEGG:R04591	GO:0004639

tr|Q9I7S9|Q9I7S9_DROME
CG1924
Search

0.70

Calnexin

0.69	GO:0006457	protein folding
0.46	GO:0016063	rhodopsin biosynthetic process
0.44	GO:0001895	retina homeostasis
0.44	GO:0010522	regulation of calcium ion transport into cytosol
0.38	GO:0048916	posterior lateral line development
0.37	GO:0050821	protein stabilization
0.36	GO:0048488	synaptic vesicle endocytosis
0.34	GO:0072583	clathrin-dependent endocytosis
0.34	GO:0007339	binding of sperm to zona pellucida
0.33	GO:0006461	protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.34	GO:0044183	protein binding involved in protein folding
0.33	GO:0030246	carbohydrate binding

0.70	GO:0005783	endoplasmic reticulum
0.42	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005886	plasma membrane
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0044233	ER-mitochondrion membrane contact site
0.35	GO:0043209	myelin sheath
0.35	GO:0045202	synapse
0.32	GO:0005634	nucleus
0.32	GO:0031975	envelope

tr|Q9I7T1|Q9I7T1_DROME
Uncharacterized protein
Search

MDH

0.28	Malate dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.35	GO:0006457	protein folding
0.32	GO:0006486	protein glycosylation

0.54	GO:0016491	oxidoreductase activity
0.36	GO:0051082	unfolded protein binding
0.32	GO:0016758	transferase activity, transferring hexosyl groups

0.32	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

tr|Q9I7T3|Q9I7T3_DROME
Uncharacterized protein, isoform A
Search

0.10	UDP-glucuronosyltransferase 1-8

0.30

GO:0008152

metabolic process

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.52	GO:0008194	UDP-glycosyltransferase activity

0.37	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044425	membrane part

0.69

GO:0016758

tr|Q9I7T6|Q9I7T6_DROME
FI16911p1
Search

0.10	ubiquitin-conjugating enzyme E2 D3

0.42	GO:0000209	protein polyubiquitination
0.39	GO:0032504	multicellular organism reproduction
0.39	GO:1902426	deactivation of mitotic spindle assembly checkpoint
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0006301	postreplication repair
0.35	GO:0010498	proteasomal protein catabolic process

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0061659	ubiquitin-like protein ligase activity
0.38	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.38	GO:0016874	ligase activity
0.38	GO:0031625	ubiquitin protein ligase binding

0.38	GO:0005615	extracellular space
0.35	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.38	EC:6	GO:0016874
0.40	KEGG:R03876	GO:0004842

sp|Q9I7T7|Y1505_DROME
La-related protein CG11505
Search

0.34	GO:0045727	positive regulation of translation
0.34	GO:0007010	cytoskeleton organization
0.34	GO:0007266	Rho protein signal transduction
0.34	GO:0022604	regulation of cell morphogenesis
0.33	GO:0007155	cell adhesion
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.33	GO:0051015	actin filament binding
0.32	GO:0003735	structural constituent of ribosome

0.41	GO:0019013	viral nucleocapsid
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0044445	cytosolic part
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q9I7U1|Q9I7U1_DROME
CG1275, isoform A
Search

0.28	Integral to membrane

0.57	GO:0010039	response to iron ion
0.52	GO:0055114	oxidation-reduction process
0.33	GO:0036260	RNA capping
0.33	GO:0001510	RNA methylation
0.32	GO:0005975	carbohydrate metabolic process

0.58	GO:0000293	ferric-chelate reductase activity
0.35	GO:0046872	metal ion binding
0.33	GO:0008061	chitin binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0008168	methyltransferase activity

0.57	GO:0031526	brush border membrane
0.42	GO:0005765	lysosomal membrane
0.40	GO:0031902	late endosome membrane
0.30	GO:0016021	integral component of membrane

0.58

EC:1.16.1.7

GO:0000293

sp|Q9I7U4|TITIN_DROME
Titin
Search

SLS

0.52	Sallimus, isoform R

0.57	GO:0016539	intein-mediated protein splicing
0.48	GO:0007522	visceral muscle development
0.47	GO:0035206	regulation of hemocyte proliferation
0.47	GO:0016203	muscle attachment
0.46	GO:0007525	somatic muscle development
0.46	GO:0007520	myoblast fusion
0.46	GO:0045214	sarcomere organization
0.45	GO:0007498	mesoderm development
0.45	GO:0007519	skeletal muscle tissue development
0.45	GO:0007076	mitotic chromosome condensation

0.47	GO:0008307	structural constituent of muscle
0.43	GO:0003779	actin binding
0.37	GO:0016301	kinase activity
0.36	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005863	striated muscle myosin thick filament
0.45	GO:0030018	Z disc
0.44	GO:0000794	condensed nuclear chromosome
0.30	GO:0016020	membrane

0.36

GO:0016773

tr|Q9I7U5|Q9I7U5_DROME
Centrobin, isoform A
Search

0.13	Centrobin, isoform A

0.88	GO:0031024	interphase microtubule organizing center assembly
0.85	GO:0071539	protein localization to centrosome
0.54	GO:0007099	centriole replication
0.34	GO:0007018	microtubule-based movement
0.33	GO:0051276	chromosome organization

0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0051015	actin filament binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005814	centriole
0.34	GO:0016459	myosin complex
0.33	GO:0005694	chromosome
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|Q9I7U7|Q9I7U7_DROME
CG1233, isoform B
Search

0.10	methyl-CpG-binding domain protein 6

0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0010729	positive regulation of hydrogen peroxide biosynthetic process
0.38	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0071222	cellular response to lipopolysaccharide
0.33	GO:0034605	cellular response to heat
0.32	GO:0006508	proteolysis

0.51	GO:0003676	nucleic acid binding
0.44	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.43	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0046872	metal ion binding
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0005515	protein binding
0.32	GO:0015075	ion transmembrane transporter activity

0.39	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion
0.32	GO:0031012	extracellular matrix
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004222

tr|Q9I7V0|Q9I7V0_DROME
Mid1 ortholog, isoform A
Search

0.82	GO:0045475	locomotor rhythm
0.82	GO:0035176	social behavior
0.53	GO:0098703	calcium ion import across plasma membrane
0.38	GO:0007586	digestion
0.37	GO:0006275	regulation of DNA replication
0.37	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0043085	positive regulation of catalytic activity
0.36	GO:0016042	lipid catabolic process
0.36	GO:0006260	DNA replication
0.34	GO:0016998	cell wall macromolecule catabolic process

0.49	GO:0005262	calcium channel activity
0.37	GO:0003688	DNA replication origin binding
0.37	GO:0008047	enzyme activator activity
0.34	GO:0003796	lysozyme activity
0.33	GO:0140135	mechanosensitive cation channel activity

0.36	GO:0042025	host cell nucleus
0.35	GO:0005576	extracellular region
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:3.2.1.17

GO:0003796

tr|Q9I7V4|Q9I7V4_DROME
MIP24941p
Search

0.50	Serine proteinase stubble

0.61	GO:0006508	proteolysis
0.48	GO:0007596	blood coagulation
0.33	GO:0050890	cognition

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0005509	calcium ion binding

0.35	GO:0046658	anchored component of plasma membrane
0.35	GO:0005576	extracellular region
0.34	GO:0019897	extrinsic component of plasma membrane
0.33	GO:0005887	integral component of plasma membrane

0.69

GO:0004252

tr|Q9I7V5|Q9I7V5_DROME
LD43412p
Search

0.49	Low-density lipoprotein receptor domain class A

0.35

GO:0016310

phosphorylation

0.37	GO:0030246	carbohydrate binding
0.35	GO:0016301	kinase activity

0.30

GO:0044425

membrane part

tr|Q9I7W2|Q9I7W2_DROME
RE09151p
Search

0.68	COMM domain-containing protein 3

0.73

GO:0006814

sodium ion transport

tr|Q9I7W3|Q9I7W3_DROME
Uncharacterized protein
Search

tr|Q9I7W4|Q9I7W4_DROME
IP21505p
Search

0.63

GO:0006397

mRNA processing

0.47

GO:0003723

RNA binding

sp|Q9I7W5|SAS10_DROME
Something about silencing protein 10
Search

0.68	Something about silencing protein 10

0.77	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.62	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.61	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.60	GO:0000967	rRNA 5'-end processing
0.54	GO:0007275	multicellular organism development
0.54	GO:0016569	covalent chromatin modification
0.44	GO:0060322	head development
0.38	GO:0035690	cellular response to drug

0.56	GO:0042802	identical protein binding
0.46	GO:0003723	RNA binding

0.75	GO:0032040	small-subunit processome
0.71	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9I7X6|CARME_DROME
Carnosine N-methyltransferase
Search

0.72	Carnosine N-methyltransferase

0.66	GO:0035498	carnosine metabolic process
0.61	GO:0032259	methylation

0.68

GO:0030735

carnosine N-methyltransferase activity

0.53	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.40	GO:0030014	CCR4-NOT complex
0.30	GO:0031224	intrinsic component of membrane

0.68	EC:2.1.1.22	GO:0030735
0.68	KEGG:R02144	GO:0030735

tr|Q9I7Y5|Q9I7Y5_DROME
Uncharacterized protein
Search

0.42	GO:0016055	Wnt signaling pathway
0.40	GO:0007275	multicellular organism development

0.59	GO:0003723	RNA binding
0.40	GO:0099600	transmembrane receptor activity
0.39	GO:0038023	signaling receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|Q9I7Z8|Q9I7Z8_DROME
LD21943p
Search

tr|Q9I7Z9|Q9I7Z9_DROME
CG3176, isoform A
Search

sp|Q9I816|OR19A_DROME
Odorant receptor 19a
Search

0.48	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.60	GO:0032590	dendrite membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9N2M8|HDC_DROME
Headcase protein
Search

0.87	GO:1904799	regulation of neuron remodeling
0.86	GO:0007430	terminal branching, open tracheal system
0.86	GO:0035071	salivary gland cell autophagic cell death
0.84	GO:0048675	axon extension
0.84	GO:0016246	RNA interference
0.81	GO:0050768	negative regulation of neurogenesis
0.59	GO:0035155	negative regulation of terminal cell fate specification, open tracheal system
0.56	GO:0035147	branch fusion, open tracheal system
0.34	GO:0034729	histone H3-K79 methylation
0.34	GO:0055085	transmembrane transport

0.44	GO:0005515	protein binding
0.34	GO:0031151	histone methyltransferase activity (H3-K79 specific)
0.34	GO:0022857	transmembrane transporter activity

0.79	GO:0030425	dendrite
0.79	GO:0030424	axon
0.78	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

sp|Q9N2P6|VEPD_DROME
Ventrally expressed gene D protein
Search

0.95	Ventrally-expressed protein D, isoform B

0.70

GO:0007275

multicellular organism development

tr|Q9N2Q3|Q9N2Q3_DROME
Scavenger receptor class C, type III
Search

SR-CIII

0.97	Scavenger receptor class C, type III

0.66	GO:0006955	immune response
0.64	GO:0006898	receptor-mediated endocytosis
0.50	GO:0050829	defense response to Gram-negative bacterium
0.50	GO:0006909	phagocytosis

0.72	GO:0005044	scavenger receptor activity
0.69	GO:0030247	polysaccharide binding

0.30

GO:0044425

membrane part

sp|Q9N658|GFI1_DROME
Zinc finger protein sens
Search

0.94	Zinc finger protein sens

0.58	GO:0051569	regulation of histone H3-K4 methylation
0.58	GO:0045872	positive regulation of rhodopsin gene expression
0.57	GO:0048513	animal organ development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0008594	photoreceptor cell morphogenesis
0.57	GO:0060582	cell fate determination involved in pattern specification
0.55	GO:0048859	formation of anatomical boundary
0.54	GO:0002520	immune system development
0.54	GO:0007422	peripheral nervous system development

0.56	GO:0043425	bHLH transcription factor binding
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0001085	RNA polymerase II transcription factor binding
0.35	GO:0008013	beta-catenin binding
0.34	GO:0046872	metal ion binding
0.33	GO:0016788	hydrolase activity, acting on ester bonds

0.54	GO:0005700	polytene chromosome
0.45	GO:0005634	nucleus
0.38	GO:0005667	transcription factor complex
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0016788

tr|Q9N675|Q9N675_DROME
Zyx102 protein
Search

0.67	Lipoma-preferred partner

0.59	GO:0045805	positive regulation of eclosion
0.58	GO:0048526	imaginal disc-derived wing expansion
0.57	GO:0035002	liquid clearance, open tracheal system
0.57	GO:0045572	positive regulation of imaginal disc growth
0.57	GO:0007430	terminal branching, open tracheal system
0.56	GO:0007593	chitin-based cuticle sclerotization
0.54	GO:0035329	hippo signaling
0.43	GO:0060030	dorsal convergence
0.42	GO:0007155	cell adhesion
0.35	GO:0008588	release of cytoplasmic sequestered NF-kappaB

0.54	GO:0046872	metal ion binding
0.41	GO:0005515	protein binding
0.34	GO:0004317	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
0.34	GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity
0.34	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity
0.34	GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity
0.34	GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity
0.34	GO:0004319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity

0.57	GO:0035003	subapical complex
0.54	GO:0097517	contractile actin filament bundle
0.54	GO:0042641	actomyosin
0.45	GO:0005925	focal adhesion
0.35	GO:0045323	interleukin-1 receptor complex
0.33	GO:0005829	cytosol

0.34	EC:4.2.1.61	GO:0004317
0.34	KEGG:R04462	GO:0004317

sp|Q9NB04|PATJ_DROME
Patj homolog
Search

0.67	Patj homolog

0.87	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity
0.87	GO:0035209	pupal development
0.87	GO:0008594	photoreceptor cell morphogenesis
0.86	GO:0016334	establishment or maintenance of polarity of follicular epithelium
0.86	GO:0034334	adherens junction maintenance
0.85	GO:0045494	photoreceptor cell maintenance
0.85	GO:0035088	establishment or maintenance of apical/basal cell polarity
0.85	GO:0001736	establishment of planar polarity
0.50	GO:0016332	establishment or maintenance of polarity of embryonic epithelium
0.50	GO:0045186	zonula adherens assembly

0.88	GO:0032033	myosin II light chain binding
0.85	GO:0005080	protein kinase C binding

0.87	GO:0035003	subapical complex
0.86	GO:0016327	apicolateral plasma membrane
0.82	GO:0016324	apical plasma membrane
0.80	GO:0005912	adherens junction
0.48	GO:0005918	septate junction
0.48	GO:0045179	apical cortex
0.44	GO:0005635	nuclear envelope

tr|Q9NB13|Q9NB13_DROME
Tetraspanin
Search

0.60	Tetraspanin

0.42

GO:0007166

cell surface receptor signaling pathway

0.41

GO:0005887

integral component of plasma membrane

sp|Q9NB71|HIW_DROME
E3 ubiquitin-protein ligase highwire
Search

HIW

0.87	E3 ubiquitin-protein ligase highwire

0.70	GO:2000331	regulation of terminal button organization
0.69	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.68	GO:0048678	response to axon injury
0.68	GO:0007616	long-term memory
0.67	GO:0030514	negative regulation of BMP signaling pathway
0.66	GO:0030509	BMP signaling pathway
0.64	GO:0050808	synapse organization
0.61	GO:0006914	autophagy
0.55	GO:0010629	negative regulation of gene expression
0.53	GO:0007628	adult walking behavior

0.51	GO:0016874	ligase activity
0.51	GO:0004842	ubiquitin-protein transferase activity
0.45	GO:0005515	protein binding
0.43	GO:0008270	zinc ion binding

0.58	GO:0031410	cytoplasmic vesicle
0.50	GO:0030424	axon
0.48	GO:0045202	synapse
0.48	GO:0030054	cell junction
0.47	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.34	GO:0015630	microtubule cytoskeleton

0.51	EC:6	GO:0016874
0.51	KEGG:R03876	GO:0004842

tr|Q9NBC8|Q9NBC8_DROME
Allatostatin A receptor 2, isoform A
Search

0.78	Sl allatostatin A receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0007194	negative regulation of adenylate cyclase activity
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.36	GO:0009755	hormone-mediated signaling pathway
0.35	GO:0006468	protein phosphorylation
0.34	GO:0051464	positive regulation of cortisol secretion
0.34	GO:0051173	positive regulation of nitrogen compound metabolic process
0.34	GO:0010604	positive regulation of macromolecule metabolic process
0.34	GO:0031325	positive regulation of cellular metabolic process
0.33	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.72	GO:0004930	G-protein coupled receptor activity
0.60	GO:0001653	peptide receptor activity
0.39	GO:0050254	rhodopsin kinase activity
0.36	GO:0042562	hormone binding
0.36	GO:0042277	peptide binding

0.47

GO:0005887

integral component of plasma membrane

0.39

EC:2.7.11.14

GO:0050254

sp|Q9NBD7|CLASP_DROME
CLIP-associating protein
Search

0.72	Putative microtubule associated-protein orbit

0.60	GO:0030723	ovarian fusome organization
0.59	GO:0007282	cystoblast division
0.59	GO:0035099	hemocyte migration
0.59	GO:0016325	oocyte microtubule cytoskeleton organization
0.59	GO:0046602	regulation of mitotic centrosome separation
0.58	GO:0000022	mitotic spindle elongation
0.58	GO:0051315	attachment of mitotic spindle microtubules to kinetochore
0.57	GO:0031116	positive regulation of microtubule polymerization
0.56	GO:0040001	establishment of mitotic spindle localization
0.56	GO:0090307	mitotic spindle assembly

0.85	GO:0043515	kinetochore binding
0.85	GO:0051010	microtubule plus-end binding
0.47	GO:0005525	GTP binding
0.34	GO:0002162	dystroglycan binding
0.32	GO:0005198	structural molecule activity

0.85	GO:0005828	kinetochore microtubule
0.83	GO:0005881	cytoplasmic microtubule
0.59	GO:0005827	polar microtubule
0.59	GO:0045172	germline ring canal
0.58	GO:0045169	fusome
0.57	GO:0035371	microtubule plus-end
0.56	GO:0030426	growth cone
0.53	GO:0000776	kinetochore
0.53	GO:0005813	centrosome
0.52	GO:0005875	microtubule associated complex

sp|Q9NBK5|TRC_DROME
Serine/threonine-protein kinase tricorner
Search

0.55	Serine/threonine-protein kinase tricorner

0.63	GO:0006468	protein phosphorylation
0.47	GO:0048800	antennal morphogenesis
0.47	GO:0070593	dendrite self-avoidance
0.47	GO:0035317	imaginal disc-derived wing hair organization
0.46	GO:0022416	chaeta development
0.46	GO:0048814	regulation of dendrite morphogenesis
0.45	GO:0048813	dendrite morphogenesis
0.41	GO:0035556	intracellular signal transduction
0.40	GO:0018209	peptidyl-serine modification

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.48	GO:0070451	cell hair
0.44	GO:0030425	dendrite
0.44	GO:0044297	cell body
0.44	GO:0030424	axon
0.43	GO:0005938	cell cortex
0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.70

GO:0004674

sp|Q9NBW1|FRIZ4_DROME
Frizzled-4
Search

0.63	Frizzled-4

0.77	GO:0016055	Wnt signaling pathway
0.51	GO:0007275	multicellular organism development
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.85	GO:0042813	Wnt-activated receptor activity
0.53	GO:0017147	Wnt-protein binding
0.36	GO:0004930	G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|Q9NCC3|Q9NCC3_DROME
Sorting nexin
Search

0.70	Sorting nexin 9 variant

0.65	GO:0000278	mitotic cell cycle
0.58	GO:0015031	protein transport
0.55	GO:1990709	presynaptic active zone organization
0.55	GO:0001956	positive regulation of neurotransmitter secretion
0.54	GO:0030032	lamellipodium assembly
0.53	GO:0071456	cellular response to hypoxia
0.52	GO:0000045	autophagosome assembly
0.43	GO:0061640	cytoskeleton-dependent cytokinesis
0.41	GO:0006897	endocytosis
0.40	GO:0046907	intracellular transport

0.76	GO:0035091	phosphatidylinositol binding
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0071212	subsynaptic reticulum
0.53	GO:0042734	presynaptic membrane
0.51	GO:0043025	neuronal cell body
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005938	cell cortex
0.38	GO:0031410	cytoplasmic vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex

0.33

GO:0016758

sp|Q9NDJ2|DOM_DROME
Helicase domino
Search

0.69	Helicase domino

0.43	GO:0035207	negative regulation of hemocyte proliferation
0.43	GO:0036098	male germ-line stem cell population maintenance
0.43	GO:0070983	dendrite guidance
0.42	GO:2000637	positive regulation of gene silencing by miRNA
0.42	GO:0035222	wing disc pattern formation
0.42	GO:0035019	somatic stem cell population maintenance
0.41	GO:0045747	positive regulation of Notch signaling pathway
0.41	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.41	GO:0043486	histone exchange
0.41	GO:0002165	instar larval or pupal development

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004386	helicase activity
0.40	GO:0004402	histone acetyltransferase activity
0.40	GO:0003677	DNA binding
0.38	GO:0008094	DNA-dependent ATPase activity
0.37	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.31	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

0.40	GO:0035267	NuA4 histone acetyltransferase complex
0.30	GO:0016020	membrane

0.40

GO:0004402

sp|Q9NDM2|GUTR1_DROME
Protein trapped in endoderm-1
Search

0.52	G protein-coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0007280	pole cell migration
0.39	GO:0035234	ectopic germ cell programmed cell death
0.37	GO:0007281	germ cell development
0.33	GO:0035590	purinergic nucleotide receptor signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016787	hydrolase activity
0.33	GO:0001653	peptide receptor activity
0.33	GO:0016502	nucleotide receptor activity
0.33	GO:0035586	purinergic receptor activity

0.37	GO:0005938	cell cortex
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

sp|Q9NEF6|VATD2_DROME
Probable V-type proton ATPase subunit D 2
Search

0.67	V-type proton ATPase subunit D

0.55	GO:0055085	transmembrane transport
0.40	GO:0061512	protein localization to cilium
0.39	GO:0060271	cilium assembly
0.35	GO:0015992	proton transport
0.35	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.34	GO:0006281	DNA repair
0.33	GO:0055114	oxidation-reduction process

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0022853	active ion transmembrane transporter activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016491	oxidoreductase activity
0.33	GO:0005515	protein binding

0.45	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.39	GO:0005813	centrosome
0.38	GO:0005929	cilium
0.36	GO:0005774	vacuolar membrane
0.35	GO:0005764	lysosome
0.34	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.34

GO:0016491

sp|Q9NFP1|VNNL1_DROME
Vanin-like protein 1
Search

0.41	Carbon-nitrogen hydrolase

0.45	GO:0006807	nitrogen compound metabolic process
0.40	GO:0009408	response to heat
0.40	GO:0016569	covalent chromatin modification
0.35	GO:0006629	lipid metabolic process
0.35	GO:0035556	intracellular signal transduction
0.34	GO:0044260	cellular macromolecule metabolic process
0.32	GO:0022900	electron transport chain
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.63	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.37	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0008121	ubiquinol-cytochrome-c reductase activity
0.33	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0043565	sequence-specific DNA binding

0.36	GO:0019898	extrinsic component of membrane
0.33	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.63	EC:3.5.1	GO:0016811
0.37	KEGG:R03435	GO:0004435

sp|Q9NFP5|SH3BG_DROME
SH3 domain-binding glutamic acid-rich protein homolog
Search

0.73	SH3 domain-binding glutamic acid-rich protein homolog

0.66	GO:0045454	cell redox homeostasis
0.58	GO:0022900	electron transport chain
0.36	GO:0006508	proteolysis
0.36	GO:0016310	phosphorylation
0.34	GO:0055085	transmembrane transport

0.69	GO:0015035	protein disulfide oxidoreductase activity
0.59	GO:0009055	electron transfer activity
0.41	GO:0017124	SH3 domain binding
0.38	GO:0008234	cysteine-type peptidase activity
0.36	GO:0016301	kinase activity

0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0008234

sp|Q9NFT7|HXK2_DROME
Hexokinase type 2
Search

0.56	Phosphotransferase

0.82	GO:0001678	cellular glucose homeostasis
0.74	GO:0046835	carbohydrate phosphorylation
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.48	GO:0060361	flight
0.37	GO:0051156	glucose 6-phosphate metabolic process
0.36	GO:0006000	fructose metabolic process
0.35	GO:0006013	mannose metabolic process

0.83	GO:0005536	glucose binding
0.79	GO:0004396	hexokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:2.7.1.1

GO:0004396

sp|Q9NFT9|HXK1_DROME
Hexokinase type 1
Search

0.40	Phosphotransferase

0.82	GO:0001678	cellular glucose homeostasis
0.74	GO:0046835	carbohydrate phosphorylation
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.43	GO:0051156	glucose 6-phosphate metabolic process
0.40	GO:0019318	hexose metabolic process
0.37	GO:0006113	fermentation
0.37	GO:0006002	fructose 6-phosphate metabolic process

0.83	GO:0005536	glucose binding
0.79	GO:0004396	hexokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0042562	hormone binding
0.33	GO:0019899	enzyme binding

0.41	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.35	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0034774	secretory granule lumen
0.33	GO:0005576	extracellular region
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.79

EC:2.7.1.1

GO:0004396

sp|Q9NFU0|FMR1_DROME
Synaptic functional regulator FMR1
Search

FMR1

0.83	Synaptic functional regulator FMR1

0.38	GO:0097091	synaptic vesicle clustering
0.38	GO:0070142	synaptic vesicle budding
0.38	GO:0090328	regulation of olfactory learning
0.38	GO:0045571	negative regulation of imaginal disc growth
0.37	GO:0050802	circadian sleep/wake cycle, sleep
0.37	GO:0072375	medium-term memory
0.37	GO:0051823	regulation of synapse structural plasticity
0.37	GO:0007279	pole cell formation
0.37	GO:0072553	terminal button organization
0.37	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch

0.59	GO:0003723	RNA binding
0.37	GO:0043621	protein self-association
0.36	GO:0045182	translation regulator activity
0.35	GO:0042802	identical protein binding

0.38	GO:0005844	polysome
0.37	GO:0071598	neuronal ribonucleoprotein granule
0.37	GO:0035068	micro-ribonucleoprotein complex
0.37	GO:0043186	P granule
0.37	GO:0043204	perikaryon
0.37	GO:0016442	RISC complex
0.36	GO:0010494	cytoplasmic stress granule
0.36	GO:0098793	presynapse
0.35	GO:0030054	cell junction
0.35	GO:0005634	nucleus

tr|Q9NFV7|Q9NFV7_DROME
GH01829p
Search

0.97	Thioester-containing protein 2

0.76	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:0050829	defense response to Gram-negative bacterium

0.77

GO:0004866

endopeptidase inhibitor activity

0.73	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|Q9NFV8|Q9NFV8_DROME
TEP1 protein
Search

TEPI

0.96	Thioester-containing protein 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.44	GO:0050829	defense response to Gram-negative bacterium

0.77

GO:0004866

endopeptidase inhibitor activity

0.73	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q9NFZ3|GBGE_DROME
Guanine nucleotide-binding protein subunit gamma-e
Search

0.69	Guanine nucleotide-binding protein subunit gamma-e

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0007601	visual perception
0.37	GO:0071244	cellular response to carbon dioxide
0.36	GO:0007602	phototransduction
0.35	GO:0006030	chitin metabolic process
0.33	GO:0005975	carbohydrate metabolic process

0.64	GO:0004871	signal transducer activity
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0008061	chitin binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.37	GO:0016028	rhabdomere
0.34	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0004553

tr|Q9NG60|Q9NG60_DROME
Eukaryotic translation initiation factor 2D
Search

0.62	Eukaryotic translation initiation factor 2D

0.71	GO:0006413	translational initiation
0.44	GO:0032790	ribosome disassembly
0.43	GO:0002181	cytoplasmic translation
0.42	GO:0022618	ribonucleoprotein complex assembly
0.39	GO:0075522	IRES-dependent viral translational initiation
0.33	GO:0006182	cGMP biosynthetic process
0.32	GO:0006468	protein phosphorylation
0.32	GO:0035556	intracellular signal transduction
0.31	GO:0006355	regulation of transcription, DNA-templated

0.71	GO:0003743	translation initiation factor activity
0.33	GO:0004383	guanylate cyclase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0003690	double-stranded DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0022627	cytosolic small ribosomal subunit
0.37	GO:0016604	nuclear body
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:4.6.1.2

GO:0004383

sp|Q9NG98|TOP3A_DROME
DNA topoisomerase 3-alpha
Search

0.38	DNA topoisomerase

0.72	GO:0006265	DNA topological change
0.57	GO:0042246	tissue regeneration
0.55	GO:0000002	mitochondrial genome maintenance
0.53	GO:0000724	double-strand break repair via homologous recombination
0.35	GO:0045892	negative regulation of transcription, DNA-templated

0.77	GO:0003917	DNA topoisomerase type I activity
0.56	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding

0.60	GO:0005694	chromosome
0.46	GO:0005634	nucleus
0.45	GO:0005739	mitochondrion
0.32	GO:0031974	membrane-enclosed lumen
0.31	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.77

EC:5.99.1.2

GO:0003917

sp|Q9NGC3|CEG1A_DROME
Centaurin-gamma-1A
Search

0.75	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3

0.73	GO:0043547	positive regulation of GTPase activity
0.56	GO:0072375	medium-term memory
0.48	GO:0007165	signal transduction
0.30	GO:0008152	metabolic process

0.74	GO:0005096	GTPase activator activity
0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032553	ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding

0.30

GO:0016020

membrane

tr|Q9NGK5|Q9NGK5_DROME
FI21425p1
Search

0.53	Neuroligin

0.69	GO:0048499	synaptic vesicle membrane organization
0.69	GO:0002121	inter-male aggressive behavior
0.69	GO:0045433	male courtship behavior, veined wing generated song production
0.68	GO:0060074	synapse maturation
0.68	GO:0048790	maintenance of presynaptic active zone structure
0.67	GO:0051124	synaptic growth at neuromuscular junction
0.66	GO:2000331	regulation of terminal button organization
0.66	GO:0007628	adult walking behavior
0.66	GO:0035176	social behavior
0.66	GO:0008345	larval locomotory behavior

0.67	GO:0042043	neurexin family protein binding
0.39	GO:0052689	carboxylic ester hydrolase activity
0.38	GO:0004872	receptor activity
0.34	GO:0015299	solute:proton antiporter activity

0.63	GO:0031594	neuromuscular junction
0.60	GO:0045211	postsynaptic membrane
0.40	GO:0009986	cell surface
0.38	GO:0005887	integral component of plasma membrane

0.39	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.39	KEGG:R00630	GO:0052689

tr|Q9NGL1|Q9NGL1_DROME
MAP kinase phosphatase-1
Search

DUSP19

0.76	MAP kinase-specific phosphatase

0.72	GO:0006470	protein dephosphorylation
0.48	GO:0001522	pseudouridine synthesis
0.46	GO:0043407	negative regulation of MAP kinase activity
0.41	GO:0008033	tRNA processing
0.36	GO:0046329	negative regulation of JNK cascade
0.36	GO:0043507	positive regulation of JUN kinase activity
0.36	GO:0032147	activation of protein kinase activity
0.35	GO:0007254	JNK cascade
0.34	GO:0001510	RNA methylation

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.66	GO:0004725	protein tyrosine phosphatase activity
0.48	GO:0009982	pseudouridine synthase activity
0.45	GO:0033549	MAP kinase phosphatase activity
0.42	GO:0003723	RNA binding
0.37	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.37	GO:0005078	MAP-kinase scaffold activity
0.36	GO:0004860	protein kinase inhibitor activity
0.36	GO:0030295	protein kinase activator activity
0.36	GO:0008330	protein tyrosine/threonine phosphatase activity

0.36	GO:0031515	tRNA (m1A) methyltransferase complex
0.30	GO:0016020	membrane

0.79

EC:3.1.3

GO:0008138

sp|Q9NGX9|CP302_DROME
Cytochrome P450 302a1, mitochondrial
Search

DIB

0.97	Disembodied

0.56	GO:0006697	ecdysone biosynthetic process
0.55	GO:0008362	chitin-based embryonic cuticle biosynthetic process
0.55	GO:0008258	head involution
0.55	GO:0007494	midgut development
0.54	GO:0007391	dorsal closure
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0007417	central nervous system development
0.34	GO:0006091	generation of precursor metabolites and energy
0.33	GO:0006518	peptide metabolic process
0.33	GO:0043604	amide biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0003958	NADPH-hemoprotein reductase activity
0.34	GO:0010181	FMN binding
0.34	GO:0009055	electron transfer activity
0.33	GO:0003735	structural constituent of ribosome

0.43	GO:0005739	mitochondrion
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9NHA8|BGBP3_DROME
Gram-negative bacteria-binding protein 3
Search

0.37	Gram-negative bacteria-binding protein 3

0.61	GO:0032491	detection of molecule of fungal origin
0.58	GO:0005975	carbohydrate metabolic process
0.43	GO:0006952	defense response
0.41	GO:0006955	immune response
0.41	GO:0045088	regulation of innate immune response
0.38	GO:0002757	immune response-activating signal transduction
0.38	GO:0031349	positive regulation of defense response
0.34	GO:0009617	response to bacterium
0.34	GO:0006438	valyl-tRNA aminoacylation
0.34	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.65	GO:0030246	carbohydrate binding
0.64	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.54	GO:0001530	lipopolysaccharide binding
0.52	GO:0001871	pattern binding
0.39	GO:0008329	signaling pattern recognition receptor activity
0.34	GO:0004832	valine-tRNA ligase activity
0.34	GO:0002161	aminoacyl-tRNA editing activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.51	GO:0009986	cell surface
0.40	GO:0005576	extracellular region
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.64	EC:3.2.1	GO:0004553
0.34	KEGG:R03665	GO:0004832

sp|Q9NHB0|BGBP1_DROME
Gram-negative bacteria-binding protein 1
Search

0.85	Gram-negative bacteria-binding protein 1

0.64	GO:0045752	positive regulation of Toll signaling pathway
0.60	GO:0050830	defense response to Gram-positive bacterium
0.60	GO:0005975	carbohydrate metabolic process
0.59	GO:0002221	pattern recognition receptor signaling pathway
0.54	GO:0006955	immune response
0.54	GO:0009253	peptidoglycan catabolic process
0.38	GO:0050829	defense response to Gram-negative bacterium
0.38	GO:0050832	defense response to fungus

0.67	GO:0001872	(1->3)-beta-D-glucan binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.61	GO:0008329	signaling pattern recognition receptor activity
0.61	GO:0001530	lipopolysaccharide binding
0.56	GO:0042834	peptidoglycan binding
0.35	GO:0005515	protein binding
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.59	GO:0046658	anchored component of plasma membrane
0.50	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.66

GO:0004553

sp|Q9NHD5|SAN_DROME
Probable N-acetyltransferase san
Search

0.35	N-acetyl transferase separation anxiety

0.53	GO:0007064	mitotic sister chromatid cohesion
0.52	GO:0006474	N-terminal protein amino acid acetylation
0.52	GO:0016573	histone acetylation
0.48	GO:0070601	centromeric sister chromatid cohesion
0.48	GO:0034085	establishment of sister chromatid cohesion

0.68	GO:0008080	N-acetyltransferase activity
0.34	GO:0005515	protein binding

0.56	GO:0031415	NatA complex
0.46	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.68

GO:0008080

sp|Q9NHE5|CAPS_DROME
Calcium-dependent secretion activator
Search

LOC108101969

0.63	Calcium-dependent secretion activator

0.85	GO:1990504	dense core granule exocytosis
0.84	GO:0016079	synaptic vesicle exocytosis
0.38	GO:0045956	positive regulation of calcium ion-dependent exocytosis
0.38	GO:0035249	synaptic transmission, glutamatergic
0.35	GO:0015031	protein transport
0.34	GO:0006629	lipid metabolic process
0.34	GO:0035556	intracellular signal transduction

0.36	GO:0008289	lipid binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0004871	signal transducer activity

0.79	GO:0098793	presynapse
0.37	GO:0070382	exocytic vesicle
0.37	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:3.1.4.11	GO:0004435
0.36	KEGG:R03435	GO:0004435

tr|Q9NHN2|Q9NHN2_DROME
Fumble
Search

FBL

0.43	Panthotenate kinase

0.75	GO:0015937	coenzyme A biosynthetic process
0.57	GO:0016310	phosphorylation
0.50	GO:0071480	cellular response to gamma radiation
0.50	GO:0045475	locomotor rhythm
0.50	GO:0070328	triglyceride homeostasis
0.49	GO:0007476	imaginal disc-derived wing morphogenesis
0.48	GO:0048477	oogenesis
0.47	GO:0007283	spermatogenesis
0.47	GO:0032465	regulation of cytokinesis
0.46	GO:0051321	meiotic cell cycle

0.79	GO:0004594	pantothenate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005819	spindle
0.40	GO:0031514	motile cilium
0.40	GO:0055037	recycling endosome
0.40	GO:0071944	cell periphery
0.39	GO:0030118	clathrin coat
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus

0.79

EC:2.7.1.33

GO:0004594

tr|Q9NHP8|Q9NHP8_DROME
GTX/Nkx6B-like homeodomain protein
Search

0.77

sericin 1

0.62	GO:0048699	generation of neurons
0.58	GO:0007417	central nervous system development
0.57	GO:0006357	regulation of transcription by RNA polymerase II
0.56	GO:0031018	endocrine pancreas development
0.55	GO:0035883	enteroendocrine cell differentiation
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.53	GO:0045892	negative regulation of transcription, DNA-templated
0.52	GO:0061387	regulation of extent of cell growth
0.52	GO:0050796	regulation of insulin secretion
0.51	GO:0010769	regulation of cell morphogenesis involved in differentiation

0.62	GO:0043565	sequence-specific DNA binding
0.60	GO:0070491	repressing transcription factor binding
0.59	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.38	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9NHV9|VAV_DROME
Protein vav
Search

0.57	Guanine nucleotide exchange factor VAV

0.77	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.61	GO:0035556	intracellular signal transduction
0.39	GO:0072499	photoreceptor cell axon guidance
0.39	GO:0035011	melanotic encapsulation of foreign target
0.38	GO:0007391	dorsal closure
0.38	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.38	GO:0007520	myoblast fusion
0.38	GO:1903391	regulation of adherens junction organization
0.38	GO:0007424	open tracheal system development

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.51	GO:0046872	metal ion binding
0.38	GO:0048365	Rac GTPase binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0003779	actin binding
0.32	GO:0016740	transferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005622	intracellular
0.33	GO:0043234	protein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|Q9NHX0|RBX1B_DROME
RING-box protein 1B
Search

0.54	Ubiquitin ligase subunit

0.51	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0016567	protein ubiquitination
0.44	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0030317	flagellated sperm motility
0.44	GO:0019915	lipid storage
0.42	GO:0000082	G1/S transition of mitotic cell cycle
0.41	GO:0045116	protein neddylation
0.35	GO:0008283	cell proliferation
0.33	GO:0016569	covalent chromatin modification
0.33	GO:0051301	cell division

0.62	GO:0008270	zinc ion binding
0.50	GO:0004842	ubiquitin-protein transferase activity
0.48	GO:0061659	ubiquitin-like protein ligase activity
0.48	GO:0097602	cullin family protein binding
0.42	GO:0019788	NEDD8 transferase activity
0.42	GO:0030674	protein binding, bridging
0.41	GO:0016874	ligase activity

0.52	GO:0031461	cullin-RING ubiquitin ligase complex
0.47	GO:0000152	nuclear ubiquitin ligase complex
0.37	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.32	GO:1905369	endopeptidase complex
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.41	EC:6	GO:0016874
0.50	KEGG:R03876	GO:0004842

sp|Q9NI63|PMYT1_DROME
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Search

0.90	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0007284	spermatogonial cell division
0.60	GO:0048142	germarium-derived cystoblast division
0.59	GO:0048137	spermatocyte division
0.57	GO:0045793	positive regulation of cell size
0.57	GO:0007143	female meiotic nuclear division
0.56	GO:0000086	G2/M transition of mitotic cell cycle
0.56	GO:0007140	male meiotic nuclear division
0.53	GO:0045930	negative regulation of mitotic cell cycle
0.37	GO:0009866	induced systemic resistance, ethylene mediated signaling pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.36	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0046872	metal ion binding
0.32	GO:0030246	carbohydrate binding
0.31	GO:0016787	hydrolase activity

0.50	GO:0005794	Golgi apparatus
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.35	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.31

GO:0016787

sp|Q9NII1|ADAR_DROME
Double-stranded RNA-specific editase Adar
Search

ADARB1

0.42	Double-stranded RNA-specific editase Adar

0.63	GO:0006396	RNA processing
0.46	GO:0006382	adenosine to inosine editing
0.46	GO:0007610	behavior
0.46	GO:0021618	hypoglossal nerve morphogenesis
0.45	GO:0097049	motor neuron apoptotic process
0.45	GO:0021965	spinal cord ventral commissure morphogenesis
0.44	GO:0021610	facial nerve morphogenesis
0.44	GO:0050884	neuromuscular process controlling posture
0.44	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.44	GO:0060384	innervation

0.78	GO:0004000	adenosine deaminase activity
0.59	GO:0003723	RNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0005272	sodium channel activity
0.33	GO:0042803	protein homodimerization activity

0.40	GO:0005730	nucleolus
0.39	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78

EC:3.5.4.4

GO:0004000

sp|Q9NIP6|CP2B_DROME
Cardio acceleratory peptide 2b
Search

0.65

Pyrokinin

sp|Q9NIV1|E2AK3_DROME
Eukaryotic translation initiation factor 2-alpha kinase
Search

0.64	Eukaryotic translation initiation factor 2 alpha kinase PEK

0.63	GO:0006468	protein phosphorylation
0.62	GO:0036499	PERK-mediated unfolded protein response
0.57	GO:0046330	positive regulation of JNK cascade
0.56	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.54	GO:0010508	positive regulation of autophagy
0.54	GO:0006413	translational initiation
0.48	GO:0036491	regulation of translation initiation in response to endoplasmic reticulum stress
0.47	GO:0006983	ER overload response
0.46	GO:0010575	positive regulation of vascular endothelial growth factor production
0.46	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0003743	translation initiation factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0019903	protein phosphatase binding
0.45	GO:0045182	translation regulator activity
0.42	GO:0042802	identical protein binding
0.36	GO:0051879	Hsp90 protein binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9NIV2|STEL8_DROME
Stellate orphon protein at 12D
Search

0.43	Casein kinase II subunit beta

0.76	GO:0045859	regulation of protein kinase activity
0.54	GO:0080163	regulation of protein serine/threonine phosphatase activity
0.42	GO:0016310	phosphorylation
0.39	GO:0043433	negative regulation of DNA binding transcription factor activity
0.38	GO:0048232	male gamete generation
0.38	GO:0033674	positive regulation of kinase activity
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0001934	positive regulation of protein phosphorylation
0.37	GO:0045132	meiotic chromosome segregation
0.36	GO:0022412	cellular process involved in reproduction in multicellular organism

0.79	GO:0019887	protein kinase regulator activity
0.43	GO:0016301	kinase activity
0.39	GO:0019209	kinase activator activity
0.35	GO:0016151	nickel cation binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0140096	catalytic activity, acting on a protein

0.83	GO:0005956	protein kinase CK2 complex
0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0016773

sp|Q9NJB5|ONEC_DROME
Homeobox protein onecut
Search

0.48	Homeobox protein onecut

0.56	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0035622	intrahepatic bile duct development
0.36	GO:0030154	cell differentiation

0.59	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003677	DNA binding

0.57

GO:0005634

nucleus

sp|Q9NJG9|SUZ12_DROME
Polycomb protein Su(z)12
Search

SUZ12

0.89	SUZ12 polycomb repressive complex 2 subunit

0.71	GO:0016571	histone methylation
0.70	GO:2001229	negative regulation of response to gamma radiation
0.58	GO:0022008	neurogenesis
0.57	GO:0016574	histone ubiquitination
0.56	GO:0045596	negative regulation of cell differentiation
0.56	GO:0018022	peptidyl-lysine methylation
0.55	GO:0008284	positive regulation of cell proliferation
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0070317	negative regulation of G0 to G1 transition
0.36	GO:0045814	negative regulation of gene expression, epigenetic

0.71	GO:0042054	histone methyltransferase activity
0.69	GO:0003682	chromatin binding
0.59	GO:0140034	methylation-dependent protein binding
0.57	GO:0042393	histone binding
0.56	GO:0016279	protein-lysine N-methyltransferase activity
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0044877	macromolecular complex binding
0.45	GO:0003723	RNA binding
0.34	GO:0046872	metal ion binding

0.77	GO:0035098	ESC/E(Z) complex
0.61	GO:0001739	sex chromatin
0.56	GO:0016604	nuclear body
0.54	GO:0005730	nucleolus
0.52	GO:0016586	RSC-type complex
0.51	GO:0032993	protein-DNA complex

0.56

GO:0016279

sp|Q9NJH0|EF1G_DROME
Elongation factor 1-gamma
Search

EF-1G

0.68	Translation elongation factor EF-1 gamma

0.70	GO:0006414	translational elongation
0.35	GO:0006749	glutathione metabolic process

0.71	GO:0003746	translation elongation factor activity
0.35	GO:0004364	glutathione transferase activity

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex

0.35

EC:2.5.1.18

GO:0004364

sp|Q9NK54|CHIF_DROME
Protein chiffon
Search

0.85	Chiffon, isoform D

0.82	GO:0007307	eggshell chorion gene amplification
0.81	GO:0072499	photoreceptor cell axon guidance
0.77	GO:0046716	muscle cell cellular homeostasis
0.76	GO:0045740	positive regulation of DNA replication
0.71	GO:0032147	activation of protein kinase activity
0.41	GO:0006260	DNA replication

0.74	GO:0030295	protein kinase activator activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

0.79

GO:0031431

Dbf4-dependent protein kinase complex

sp|Q9NK57|NIF3L_DROME
NIF3-like protein 1
Search

0.44	Putative GTP cyclohydrolase 1 type 2

0.41	GO:0016573	histone acetylation
0.39	GO:0016226	iron-sulfur cluster assembly
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.35	GO:0030182	neuron differentiation
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:1902679	negative regulation of RNA biosynthetic process

0.59	GO:0042802	identical protein binding
0.42	GO:0004402	histone acetyltransferase activity
0.37	GO:0016787	hydrolase activity
0.35	GO:0008134	transcription factor binding

0.49	GO:0005739	mitochondrion
0.43	GO:0072487	MSL complex
0.41	GO:0097361	CIA complex

0.42

GO:0004402

sp|Q9NKV0|MLF_DROME
Myeloid leukemia factor
Search

MLF

0.62	Myeloid leukemia factor

0.87	GO:2000495	regulation of cell proliferation involved in compound eye morphogenesis
0.79	GO:0050821	protein stabilization
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0006886	intracellular protein transport
0.34	GO:0006414	translational elongation

0.34

GO:0003746

translation elongation factor activity

0.85	GO:0005705	polytene chromosome interband
0.78	GO:0048471	perinuclear region of cytoplasm
0.61	GO:0005634	nucleus

sp|Q9NLA6|OAF_DROME
Out at first protein
Search

OAF

0.70	Out at first

0.54	GO:0016321	female meiosis chromosome segregation
0.50	GO:0007275	multicellular organism development
0.35	GO:0001678	cellular glucose homeostasis
0.34	GO:0060322	head development
0.34	GO:0016310	phosphorylation
0.34	GO:0046488	phosphatidylinositol metabolic process
0.34	GO:0030258	lipid modification
0.34	GO:0046031	ADP metabolic process
0.34	GO:0006090	pyruvate metabolic process
0.34	GO:0016052	carbohydrate catabolic process

0.35	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.35	GO:0005536	glucose binding
0.34	GO:0004396	hexokinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity

0.42	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane
0.30	GO:0005623	cell

0.35	EC:2.7.1.150	GO:0000285
0.35	KEGG:R05802	GO:0000285

tr|Q9TVI0|Q9TVI0_DROME
FI23915p1
Search

GRIK2

0.64	Ionotropic glutamate receptor subunit ia

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0007274	neuromuscular synaptic transmission
0.54	GO:0030510	regulation of BMP signaling pathway
0.54	GO:0019722	calcium-mediated signaling
0.53	GO:0043179	rhythmic excitation
0.51	GO:0006816	calcium ion transport
0.39	GO:0035249	synaptic transmission, glutamatergic
0.37	GO:0060025	regulation of synaptic activity

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.55	GO:0099604	ligand-gated calcium channel activity
0.37	GO:0005272	sodium channel activity
0.37	GO:0098782	mechanosensitived potassium channel activity
0.34	GO:0046332	SMAD binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.58	GO:0097482	muscle cell postsynaptic specialization
0.55	GO:0008328	ionotropic glutamate receptor complex
0.37	GO:0005622	intracellular

sp|Q9TVM2|XPO1_DROME
Exportin-1
Search

XPO1

0.75	Putative nuclear transport receptor crm1/msn5 importin beta superfamily

0.69	GO:0006886	intracellular protein transport
0.56	GO:0006611	protein export from nucleus
0.54	GO:0033750	ribosome localization
0.53	GO:0071166	ribonucleoprotein complex localization
0.53	GO:0051169	nuclear transport
0.52	GO:0051656	establishment of organelle localization
0.50	GO:0051236	establishment of RNA localization
0.50	GO:0050657	nucleic acid transport
0.50	GO:0046825	regulation of protein export from nucleus
0.47	GO:1900037	regulation of cellular response to hypoxia

0.79	GO:0008536	Ran GTPase binding
0.52	GO:0005049	nuclear export signal receptor activity
0.47	GO:0008565	protein transporter activity
0.35	GO:0005487	structural constituent of nuclear pore
0.35	GO:0019904	protein domain specific binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.49	GO:0005642	annulate lamellae
0.45	GO:0000776	kinetochore
0.43	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane
0.42	GO:0005829	cytosol
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0030529	intracellular ribonucleoprotein complex

sp|Q9TVP3|JDP_DROME
J domain-containing protein
Search

0.43	Molecular chaperone

0.54	GO:0006457	protein folding
0.48	GO:0009408	response to heat
0.40	GO:0006260	DNA replication
0.39	GO:0006886	intracellular protein transport
0.37	GO:0072594	establishment of protein localization to organelle
0.37	GO:0071806	protein transmembrane transport
0.37	GO:0032781	positive regulation of ATPase activity
0.36	GO:1990542	mitochondrial transmembrane transport
0.36	GO:0070585	protein localization to mitochondrion
0.36	GO:0016192	vesicle-mediated transport

0.56	GO:0051082	unfolded protein binding
0.53	GO:0031072	heat shock protein binding
0.48	GO:0046872	metal ion binding
0.42	GO:0003676	nucleic acid binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004222	metalloendopeptidase activity
0.37	GO:0001671	ATPase activator activity
0.35	GO:0005198	structural molecule activity

0.38	GO:0098805	whole membrane
0.38	GO:0030140	trans-Golgi network transport vesicle
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0030118	clathrin coat
0.37	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0044431	Golgi apparatus part
0.36	GO:0032592	integral component of mitochondrial membrane
0.36	GO:0098797	plasma membrane protein complex
0.36	GO:0030176	integral component of endoplasmic reticulum membrane
0.35	GO:0019867	outer membrane

0.37

GO:0004222

sp|Q9TVQ5|SPT4H_DROME
Transcription elongation factor SPT4
Search

0.68	Transcription elongation factor SPT4

0.79	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0006414	translational elongation
0.47	GO:0032785	negative regulation of DNA-templated transcription, elongation
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0006325	chromatin organization
0.39	GO:0006850	mitochondrial pyruvate transmembrane transport
0.38	GO:0006397	mRNA processing
0.37	GO:0042254	ribosome biogenesis
0.37	GO:0090262	regulation of transcription-coupled nucleotide-excision repair

0.62	GO:0008270	zinc ion binding
0.56	GO:0003746	translation elongation factor activity
0.48	GO:0000993	RNA polymerase II core binding
0.40	GO:0003727	single-stranded RNA binding
0.37	GO:0000182	rDNA binding
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.46	GO:0005703	polytene chromosome puff
0.46	GO:0005705	polytene chromosome interband
0.42	GO:0043233	organelle lumen
0.40	GO:0043234	protein complex
0.37	GO:0031933	telomeric heterochromatin
0.37	GO:0031934	mating-type region heterochromatin
0.36	GO:0033553	rDNA heterochromatin
0.36	GO:0005840	ribosome
0.35	GO:0000775	chromosome, centromeric region

tr|Q9TW27|Q9TW27_DROME
DISCO interacting protein 1, isoform D
Search

DIP1

0.92	Chromatin component KLETT

0.70	GO:0098586	cellular response to virus
0.65	GO:0051607	defense response to virus

0.69	GO:0070883	pre-miRNA binding
0.64	GO:0003725	double-stranded RNA binding
0.51	GO:0005515	protein binding

0.53	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

sp|Q9U1H0|CIC_DROME
Putative transcription factor capicua
Search

0.75	Putative transcription factor capicua

0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.50	GO:0007362	terminal region determination
0.49	GO:0046843	dorsal appendage formation
0.49	GO:0048190	wing disc dorsal/ventral pattern formation
0.49	GO:0007474	imaginal disc-derived wing vein specification
0.47	GO:0030308	negative regulation of cell growth
0.47	GO:0048592	eye morphogenesis
0.43	GO:0048286	lung alveolus development
0.43	GO:0035176	social behavior

0.55	GO:0003677	DNA binding
0.48	GO:0070491	repressing transcription factor binding
0.47	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.39	GO:0043233	organelle lumen
0.38	GO:0043234	protein complex
0.37	GO:0044446	intracellular organelle part
0.36	GO:0000428	DNA-directed RNA polymerase complex

sp|Q9U1H8|FACE2_DROME
CAAX prenyl protease 2
Search

0.77	Prenyl protein peptidase

0.51	GO:0006508	proteolysis
0.49	GO:0080120	CAAX-box protein maturation
0.36	GO:0042138	meiotic DNA double-strand break formation
0.33	GO:0032328	alanine transport
0.33	GO:0006814	sodium ion transport
0.33	GO:0070647	protein modification by small protein conjugation or removal
0.33	GO:0071432	peptide mating pheromone maturation involved in conjugation with cellular fusion

0.51	GO:0008233	peptidase activity
0.33	GO:0015655	alanine:sodium symporter activity

0.45	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0070461	SAGA-type complex
0.33	GO:0005829	cytosol
0.33	GO:0005887	integral component of plasma membrane

0.51

GO:0008233

sp|Q9U1H9|NXF1_DROME
Nuclear RNA export factor 1
Search

LOC108091189

0.64	Nuclear RNA export factor

0.80	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0051028	mRNA transport
0.74	GO:0006405	RNA export from nucleus
0.57	GO:0046833	positive regulation of RNA export from nucleus
0.53	GO:0010467	gene expression
0.52	GO:0043631	RNA polyadenylation
0.47	GO:0016071	mRNA metabolic process
0.32	GO:0055085	transmembrane transport

0.59	GO:0003723	RNA binding
0.54	GO:0047485	protein N-terminus binding
0.33	GO:0022857	transmembrane transporter activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.46	GO:0012505	endomembrane system
0.46	GO:0031974	membrane-enclosed lumen
0.44	GO:0031967	organelle envelope
0.44	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|Q9U1I1|ESN_DROME
Protein espinas
Search

0.54	GO:0070593	dendrite self-avoidance
0.46	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.46	GO:0001736	establishment of planar polarity
0.46	GO:0009948	anterior/posterior axis specification
0.46	GO:1902669	positive regulation of axon guidance
0.45	GO:0035317	imaginal disc-derived wing hair organization
0.45	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.45	GO:0045773	positive regulation of axon extension
0.45	GO:0098930	axonal transport
0.45	GO:0045746	negative regulation of Notch signaling pathway

0.62	GO:0008270	zinc ion binding
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0005515	protein binding

0.43	GO:0030424	axon
0.38	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004222

sp|Q9U1K1|SPIR_DROME
Protein spire
Search

0.80	GO:0045010	actin nucleation
0.69	GO:0016192	vesicle-mediated transport
0.58	GO:0051639	actin filament network formation
0.58	GO:0030717	karyosome formation
0.58	GO:0007316	pole plasm RNA localization
0.40	GO:0060811	intracellular mRNA localization involved in anterior/posterior axis specification
0.40	GO:0007304	chorion-containing eggshell formation
0.37	GO:0015031	protein transport
0.34	GO:0045454	cell redox homeostasis
0.33	GO:0016310	phosphorylation

0.74	GO:0003779	actin binding
0.51	GO:0008017	microtubule binding
0.33	GO:0016301	kinase activity

0.51	GO:0005938	cell cortex
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005856	cytoskeleton
0.35	GO:0005886	plasma membrane
0.32	GO:0005829	cytosol

tr|Q9U1K7|Q9U1K7_DROME
CG3939, isoform A
Search

0.30	thioredoxin domain-containing protein 17

0.49

GO:0055114

oxidation-reduction process

0.73	GO:0047134	protein-disulfide reductase activity
0.43	GO:0008270	zinc ion binding
0.40	GO:0003677	DNA binding
0.38	GO:0016787	hydrolase activity

0.62

GO:0005829

cytosol

0.73

EC:1.8.1.8

GO:0047134

tr|Q9U1L2|Q9U1L2_DROME
CG3699
Search

0.22	Cyclopentanol dehydrogenase

0.51	GO:0055114	oxidation-reduction process
0.38	GO:0009062	fatty acid catabolic process
0.38	GO:0030258	lipid modification

0.52	GO:0016491	oxidoreductase activity
0.37	GO:0004312	fatty acid synthase activity
0.35	GO:0031177	phosphopantetheine binding
0.32	GO:0003677	DNA binding

0.33	GO:0005615	extracellular space
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016491

tr|Q9U1L6|Q9U1L6_DROME
EG:BACR42I17.8 protein
Search

0.34

GO:0098655

cation transmembrane transport

0.34

GO:0008324

cation transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|Q9U1M2|TM120_DROME
Transmembrane protein 120 homolog
Search

0.39	Transmembrane protein 120

0.36	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0045089	positive regulation of innate immune response
0.34	GO:0045444	fat cell differentiation
0.32	GO:0055114	oxidation-reduction process

0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0004497	monooxygenase activity
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.30

GO:0044425

membrane part

0.32

GO:0016705

sp|Q9U3V5|TIPT_DROME
Protein tiptop
Search

0.85	GO:0048730	epidermis morphogenesis
0.84	GO:0048749	compound eye development
0.78	GO:0000122	negative regulation of transcription by RNA polymerase II
0.68	GO:0061330	Malpighian tubule stellate cell differentiation
0.67	GO:0007380	specification of segmental identity, head
0.40	GO:0007384	specification of segmental identity, thorax
0.40	GO:2000497	positive regulation of cell proliferation involved in compound eye morphogenesis
0.40	GO:0007473	wing disc proximal/distal pattern formation
0.39	GO:0007479	leg disc proximal/distal pattern formation
0.39	GO:0008258	head involution

0.51	GO:0003676	nucleic acid binding
0.45	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0003682	chromatin binding
0.40	GO:0046872	metal ion binding
0.32	GO:0005515	protein binding

0.48	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.32	GO:0043233	organelle lumen
0.31	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q9U3V8|XMAS1_DROME
Protein xmas-1
Search

0.61	GO:0048477	oogenesis
0.61	GO:0007283	spermatogenesis
0.54	GO:0007275	multicellular organism development

0.30

GO:0031224

intrinsic component of membrane

sp|Q9U3V9|XMAS2_DROME
Protein xmas-2
Search

0.54	GO:0016973	poly(A)+ mRNA export from nucleus
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0048477	oogenesis
0.39	GO:0007283	spermatogenesis
0.37	GO:0007275	multicellular organism development
0.34	GO:0002376	immune system process
0.34	GO:0006606	protein import into nucleus
0.33	GO:0043401	steroid hormone mediated signaling pathway
0.32	GO:0006351	transcription, DNA-templated

0.50	GO:0003676	nucleic acid binding
0.36	GO:0005515	protein binding
0.34	GO:0016866	intramolecular transferase activity
0.32	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.55	GO:0070390	transcription export complex 2
0.54	GO:0005635	nuclear envelope
0.53	GO:0034399	nuclear periphery
0.41	GO:0005829	cytosol
0.39	GO:0031090	organelle membrane
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.34

EC:5.4

GO:0016866

sp|Q9U3W6|MAB21_DROME
Protein mab-21
Search

0.78	Cell fate determining protein mab21l2

0.77	GO:0010172	embryonic body morphogenesis
0.76	GO:0001654	eye development
0.73	GO:0008284	positive regulation of cell proliferation
0.41	GO:0048701	embryonic cranial skeleton morphogenesis
0.40	GO:0090596	sensory organ morphogenesis

0.60	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q9U3Z7|NH2L1_DROME
NHP2-like protein 1 homolog
Search

0.42	Small nuclear ribonucleoprotein 13

0.67	GO:0042254	ribosome biogenesis
0.45	GO:0060415	muscle tissue morphogenesis
0.44	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0045727	positive regulation of translation
0.42	GO:0007399	nervous system development
0.42	GO:0016072	rRNA metabolic process
0.41	GO:0034470	ncRNA processing
0.39	GO:0000492	box C/D snoRNP assembly
0.38	GO:0007338	single fertilization
0.37	GO:0043043	peptide biosynthetic process

0.59	GO:0003723	RNA binding
0.38	GO:0051117	ATPase binding
0.34	GO:0046872	metal ion binding
0.33	GO:0008094	DNA-dependent ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005730	nucleolus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0120114	Sm-like protein family complex
0.41	GO:0044444	cytoplasmic part
0.37	GO:0019013	viral nucleocapsid
0.35	GO:0043234	protein complex
0.33	GO:0005654	nucleoplasm

sp|Q9U405|GRAU_DROME
Transcription factor grauzone
Search

GRAU

0.76	Transcription factor grauzone

0.61	GO:0007343	egg activation
0.60	GO:0007143	female meiotic nuclear division
0.54	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0007279	pole cell formation
0.38	GO:0045143	homologous chromosome segregation
0.33	GO:0006486	protein glycosylation
0.32	GO:0000122	negative regulation of transcription by RNA polymerase II
0.32	GO:0006383	transcription by RNA polymerase III

0.59	GO:0008270	zinc ion binding
0.56	GO:0000987	proximal promoter sequence-specific DNA binding
0.35	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008375	acetylglucosaminyltransferase activity
0.32	GO:0140098	catalytic activity, acting on RNA

0.58	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion
0.32	GO:0000428	DNA-directed RNA polymerase complex
0.32	GO:0031974	membrane-enclosed lumen
0.31	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.35

EC:2.7

GO:0016772

sp|Q9U4F3|SURF1_DROME
SURF1-like protein
Search

0.52	GO:0042331	phototaxis
0.51	GO:0002168	instar larval development
0.50	GO:0007632	visual behavior
0.45	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.43	GO:0021522	spinal cord motor neuron differentiation
0.41	GO:0048568	embryonic organ development
0.40	GO:1902600	hydrogen ion transmembrane transport
0.40	GO:0022900	electron transport chain
0.39	GO:0006754	ATP biosynthetic process
0.38	GO:0006119	oxidative phosphorylation

0.41	GO:0015002	heme-copper terminal oxidase activity
0.41	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.41	GO:0015078	hydrogen ion transmembrane transporter activity
0.40	GO:0009055	electron transfer activity
0.37	GO:0051287	NAD binding
0.37	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.34	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
0.33	GO:0000049	tRNA binding
0.33	GO:0005515	protein binding

0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0070469	respiratory chain
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.41

GO:0016676

tr|Q9U4F8|Q9U4F8_DROME
BcDNA.LD34475
Search

UBE4A

0.81	Ubiquitin elongating factor core

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination
0.42	GO:0036503	ERAD pathway
0.34	GO:0032012	regulation of ARF protein signal transduction
0.33	GO:0065009	regulation of molecular function

0.85	GO:0034450	ubiquitin-ubiquitin ligase activity
0.34	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.76	GO:0000151	ubiquitin ligase complex
0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q9U4G1|BDL_DROME
Protein borderless
Search

0.59	Neuronal cell adhesion molecule

0.55	GO:0045467	R7 cell development
0.55	GO:0042065	glial cell growth
0.54	GO:0007158	neuron cell-cell adhesion
0.52	GO:0008366	axon ensheathment
0.49	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0007414	axonal defasciculation
0.33	GO:0032989	cellular component morphogenesis
0.33	GO:0007629	flight behavior
0.33	GO:0070593	dendrite self-avoidance
0.33	GO:0008039	synaptic target recognition

0.54	GO:0098632	cell-cell adhesion mediator activity
0.33	GO:0052689	carboxylic ester hydrolase activity
0.33	GO:0097493	structural molecule activity conferring elasticity
0.33	GO:0051371	muscle alpha-actinin binding
0.33	GO:0008307	structural constituent of muscle
0.33	GO:0004672	protein kinase activity
0.33	GO:0008168	methyltransferase activity
0.32	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.32	GO:0051015	actin filament binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.45	GO:0005887	integral component of plasma membrane
0.37	GO:0030424	axon
0.33	GO:0005576	extracellular region
0.33	GO:0005859	muscle myosin complex
0.33	GO:0031430	M band
0.33	GO:0030018	Z disc

0.33	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.33	KEGG:R00630	GO:0052689

tr|Q9U4G5|Q9U4G5_DROME
Axud1, isoform A
Search

0.71	GO:0008285	negative regulation of cell proliferation
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0010923	negative regulation of phosphatase activity
0.53	GO:0006366	transcription by RNA polymerase II
0.41	GO:0060215	primitive hemopoiesis
0.39	GO:0030901	midbrain development
0.39	GO:0021536	diencephalon development
0.37	GO:0006915	apoptotic process

0.55	GO:0019902	phosphatase binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0043565	sequence-specific DNA binding
0.37	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9U4H5|AMX_DROME
TM2 domain-containing protein almondex
Search

0.51	TM2 domain-containing protein almondex

0.54	GO:0001713	ectodermal cell fate determination
0.52	GO:0046331	lateral inhibition
0.51	GO:0007220	Notch receptor processing
0.50	GO:0045747	positive regulation of Notch signaling pathway
0.49	GO:0007498	mesoderm development
0.36	GO:0007219	Notch signaling pathway
0.34	GO:0006030	chitin metabolic process
0.33	GO:0006435	threonyl-tRNA aminoacylation
0.33	GO:0043412	macromolecule modification
0.32	GO:0016310	phosphorylation

0.34	GO:0008061	chitin binding
0.33	GO:0004829	threonine-tRNA ligase activity
0.33	GO:0019239	deaminase activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008168	methyltransferase activity

0.37	GO:0044214	spanning component of plasma membrane
0.33	GO:0005576	extracellular region
0.33	GO:0033588	Elongator holoenzyme complex
0.32	GO:0005737	cytoplasm

0.33

EC:6.1.1.3

GO:0004829

sp|Q9U4L6|TO401_DROME
Mitochondrial import receptor subunit TOM40 homolog 1
Search

0.78	Eukaryotic porin

0.82	GO:0030150	protein import into mitochondrial matrix
0.46	GO:0071456	cellular response to hypoxia
0.35	GO:0006468	protein phosphorylation
0.34	GO:0006811	ion transport
0.34	GO:0016236	macroautophagy

0.74	GO:0008320	protein transmembrane transporter activity
0.37	GO:0015288	porin activity
0.36	GO:0044877	macromolecular complex binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0015399	primary active transmembrane transporter activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.78	GO:0005741	mitochondrial outer membrane
0.44	GO:0098798	mitochondrial protein complex
0.44	GO:0044455	mitochondrial membrane part
0.42	GO:0042719	mitochondrial intermembrane space protein transporter complex
0.40	GO:0098796	membrane protein complex
0.40	GO:0031301	integral component of organelle membrane
0.39	GO:0005829	cytosol
0.38	GO:0019866	organelle inner membrane
0.34	GO:0070062	extracellular exosome

0.35

GO:0004674

tr|Q9U599|Q9U599_DROME
AT01821p
Search

0.49	GO:0007018	microtubule-based movement
0.42	GO:0045022	early endosome to late endosome transport
0.42	GO:0001919	regulation of receptor recycling
0.42	GO:0007173	epidermal growth factor receptor signaling pathway
0.42	GO:0071346	cellular response to interferon-gamma
0.42	GO:0006895	Golgi to endosome transport
0.42	GO:0007492	endoderm development
0.41	GO:0001704	formation of primary germ layer
0.41	GO:0008543	fibroblast growth factor receptor signaling pathway
0.41	GO:0032801	receptor catabolic process

0.49	GO:0003777	microtubule motor activity
0.48	GO:0008017	microtubule binding
0.47	GO:0035091	phosphatidylinositol binding
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008144	drug binding
0.41	GO:0017137	Rab GTPase binding
0.38	GO:0016887	ATPase activity
0.37	GO:0004519	endonuclease activity

0.44	GO:0005811	lipid droplet
0.41	GO:0045335	phagocytic vesicle
0.40	GO:0005769	early endosome
0.40	GO:0005871	kinesin complex
0.39	GO:0005829	cytosol
0.37	GO:0005666	DNA-directed RNA polymerase III complex
0.36	GO:0016459	myosin complex
0.34	GO:0009706	chloroplast inner membrane
0.34	GO:0010008	endosome membrane
0.34	GO:0005681	spliceosomal complex

0.38

GO:0016887

sp|Q9U5L1|SRPRA_DROME
Signal recognition particle receptor subunit alpha homolog
Search

0.80	Signal recognition particle receptor alpha subunit

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.45	GO:0007409	axonogenesis
0.45	GO:0050708	regulation of protein secretion

0.82	GO:0005047	signal recognition particle binding
0.66	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003723	RNA binding

0.83	GO:0005785	signal recognition particle receptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9U5V6|GDLO_DROME
Gonadal protein gdl-ORF39
Search

sp|Q9U5W9|TAF10_DROME
Transcription initiation factor TFIID subunit 10
Search

0.67	Transcription initiation factor TFIID subunit

0.67	GO:0006352	DNA-templated transcription, initiation
0.59	GO:0006413	translational initiation
0.51	GO:0006366	transcription by RNA polymerase II
0.50	GO:2001141	regulation of RNA biosynthetic process
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.49	GO:0070365	hepatocyte differentiation
0.48	GO:0034622	cellular macromolecular complex assembly
0.47	GO:0035264	multicellular organism growth
0.47	GO:0043966	histone H3 acetylation

0.59	GO:0003743	translation initiation factor activity
0.51	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.48	GO:0030331	estrogen receptor binding
0.45	GO:0004402	histone acetyltransferase activity
0.45	GO:0003713	transcription coactivator activity
0.45	GO:0070063	RNA polymerase binding
0.38	GO:0003677	DNA binding
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.59	GO:0005634	nucleus
0.51	GO:0000428	DNA-directed RNA polymerase complex
0.51	GO:0005667	transcription factor complex
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0031248	protein acetyltransferase complex
0.43	GO:0044446	intracellular organelle part

0.45

GO:0004402

sp|Q9U616|GCSH_DROME
Glycine cleavage system H protein, mitochondrial
Search

0.46	Glycine cleavage system H protein, mitochondrial

0.77	GO:0019464	glycine decarboxylation via glycine cleavage system
0.34	GO:0035246	peptidyl-arginine N-methylation

0.33

GO:0008168

methyltransferase activity

0.78	GO:0005960	glycine cleavage complex
0.55	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.33

GO:0008168

tr|Q9U622|Q9U622_DROME
GH25507p
Search

0.55	Solute carrier family 2 facilitated glucose transporter member 3

0.55	GO:0055085	transmembrane transport
0.53	GO:0008643	carbohydrate transport
0.42	GO:0042593	glucose homeostasis
0.36	GO:0032502	developmental process
0.36	GO:0032869	cellular response to insulin stimulus
0.35	GO:0010021	amylopectin biosynthetic process
0.35	GO:0032501	multicellular organismal process
0.35	GO:0071356	cellular response to tumor necrosis factor
0.34	GO:0071470	cellular response to osmotic stress
0.34	GO:0015798	myo-inositol transport

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0004435	phosphatidylinositol phospholipase C activity
0.32	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0004871	signal transducer activity
0.31	GO:0003676	nucleic acid binding

0.35	GO:0032593	insulin-responsive compartment
0.35	GO:0042383	sarcolemma
0.35	GO:0098805	whole membrane
0.35	GO:0030140	trans-Golgi network transport vesicle
0.35	GO:0009897	external side of plasma membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005768	endosome
0.34	GO:0000325	plant-type vacuole

0.33	EC:3.1.4.11	GO:0004435
0.33	KEGG:R03435	GO:0004435

sp|Q9U6A0|NCKX_DROME
Sodium/potassium/calcium exchanger Nckx30C
Search

0.92	Sodium/potassium/calcium exchanger Nckx30C

0.74	GO:0035725	sodium ion transmembrane transport
0.50	GO:0048749	compound eye development
0.47	GO:0070588	calcium ion transmembrane transport
0.37	GO:0006874	cellular calcium ion homeostasis
0.36	GO:0007601	visual perception
0.36	GO:0006813	potassium ion transport

0.84	GO:0008273	calcium, potassium:sodium antiporter activity
0.37	GO:0031402	sodium ion binding
0.37	GO:0005262	calcium channel activity
0.37	GO:0030955	potassium ion binding
0.36	GO:0015293	symporter activity
0.36	GO:0005509	calcium ion binding

0.35

GO:0005887

integral component of plasma membrane

sp|Q9U6B8|CRCM1_DROME
Calcium release-activated calcium channel protein 1
Search

0.78	Calcium release-activated calcium channel protein 1

0.45	GO:0002115	store-operated calcium entry
0.40	GO:0070509	calcium ion import
0.39	GO:0070588	calcium ion transmembrane transport
0.38	GO:0061180	mammary gland epithelium development
0.37	GO:0051928	positive regulation of calcium ion transport
0.37	GO:0051533	positive regulation of NFAT protein import into nucleus
0.35	GO:0007399	nervous system development
0.33	GO:0002250	adaptive immune response
0.32	GO:0006508	proteolysis

0.42	GO:0015279	store-operated calcium channel activity
0.35	GO:0042802	identical protein binding
0.34	GO:0016787	hydrolase activity
0.32	GO:0140096	catalytic activity, acting on a protein

0.40	GO:0016323	basolateral plasma membrane
0.37	GO:0005829	cytosol
0.36	GO:0043234	protein complex
0.35	GO:0005887	integral component of plasma membrane

0.34

GO:0016787

sp|Q9U6L4|TTY1_DROME
Protein tweety
Search

0.76	GO:1902476	chloride transmembrane transport
0.34	GO:0032793	positive regulation of CREB transcription factor activity
0.33	GO:0051289	protein homotetramerization
0.33	GO:0042594	response to starvation
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006979	response to oxidative stress
0.32	GO:0032259	methylation
0.32	GO:0061332	Malpighian tubule bud morphogenesis
0.32	GO:0060288	formation of a compartment boundary
0.32	GO:0048098	antennal joint development

0.76	GO:0005254	chloride channel activity
0.34	GO:0008140	cAMP response element binding protein binding
0.33	GO:0004521	endoribonuclease activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding
0.31	GO:0004672	protein kinase activity

0.81	GO:0034707	chloride channel complex
0.53	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.32	GO:1905369	endopeptidase complex
0.31	GO:0098588	bounding membrane of organelle
0.31	GO:0031984	organelle subcompartment
0.31	GO:0012505	endomembrane system
0.31	GO:0043234	protein complex

0.32

GO:0008168

sp|Q9U6L5|PEB1_DROME
Ejaculatory bulb-specific protein 1
Search

EBP

0.92	Ejaculatory bulb-specific protein 1

0.63	GO:0045297	post-mating behavior
0.53	GO:0030036	actin cytoskeleton organization
0.47	GO:0000395	mRNA 5'-splice site recognition
0.47	GO:0007320	insemination
0.46	GO:0007617	mating behavior
0.45	GO:0000387	spliceosomal snRNP assembly
0.43	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.42	GO:0060271	cilium assembly
0.42	GO:0030334	regulation of cell migration
0.41	GO:0035335	peptidyl-tyrosine dephosphorylation

0.54	GO:0017048	Rho GTPase binding
0.53	GO:0003779	actin binding
0.46	GO:0030619	U1 snRNA binding
0.44	GO:0042802	identical protein binding
0.44	GO:0003729	mRNA binding
0.42	GO:0008270	zinc ion binding
0.41	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0004402	histone acetyltransferase activity
0.39	GO:0003712	transcription cofactor activity
0.37	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor

0.50	GO:0005576	extracellular region
0.48	GO:0001725	stress fiber
0.47	GO:0036064	ciliary basal body
0.46	GO:0000243	commitment complex
0.46	GO:0071004	U2-type prespliceosome
0.46	GO:0031514	motile cilium
0.45	GO:0005685	U1 snRNP
0.42	GO:0005829	cytosol
0.39	GO:0005581	collagen trimer
0.39	GO:0071944	cell periphery

0.41

EC:3.1.3.48

GO:0004725

sp|Q9U6M0|ECSIT_DROME
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
Search

ECSIT

0.89	Intermediate in Toll signal transduction pathway

0.76	GO:0045087	innate immune response
0.51	GO:0051341	regulation of oxidoreductase activity
0.39	GO:0055114	oxidation-reduction process

0.44	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.40	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.37	GO:0005829	cytosol
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.44

EC:1.6

GO:0016651

tr|Q9U6P7|Q9U6P7_DROME
FI18813p1
Search

SYT11

0.57	synaptotagmin-4

0.49	GO:0031340	positive regulation of vesicle fusion
0.48	GO:0046928	regulation of neurotransmitter secretion
0.47	GO:0048167	regulation of synaptic plasticity
0.44	GO:0006887	exocytosis
0.41	GO:0048489	synaptic vesicle transport
0.40	GO:0099504	synaptic vesicle cycle
0.40	GO:0099643	signal release from synapse
0.40	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.39	GO:0006836	neurotransmitter transport
0.39	GO:0017158	regulation of calcium ion-dependent exocytosis

0.49	GO:0001786	phosphatidylserine binding
0.48	GO:0005544	calcium-dependent phospholipid binding
0.48	GO:0000149	SNARE binding
0.38	GO:0030276	clathrin binding
0.37	GO:0005509	calcium ion binding
0.35	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity
0.32	GO:0016763	transferase activity, transferring pentosyl groups

0.48	GO:0031594	neuromuscular junction
0.47	GO:0016324	apical plasma membrane
0.46	GO:0045211	postsynaptic membrane
0.44	GO:0031982	vesicle
0.40	GO:0098793	presynapse
0.36	GO:0012505	endomembrane system
0.34	GO:0044444	cytoplasmic part
0.34	GO:0043229	intracellular organelle
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.154	GO:0035005
0.35	KEGG:R05795	GO:0035005

tr|Q9U6R9|Q9U6R9_DROME
GH13039p
Search

0.39	Gamma-soluble nsf attachment protein (Snap)

0.69	GO:0006886	intracellular protein transport
0.43	GO:0048190	wing disc dorsal/ventral pattern formation
0.40	GO:0061025	membrane fusion
0.38	GO:0016192	vesicle-mediated transport
0.37	GO:0097480	establishment of synaptic vesicle localization
0.37	GO:0099504	synaptic vesicle cycle
0.37	GO:0099643	signal release from synapse
0.37	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.36	GO:0006836	neurotransmitter transport
0.36	GO:0006461	protein complex assembly

0.45	GO:0005483	soluble NSF attachment protein activity
0.43	GO:0019905	syntaxin binding
0.30	GO:0003824	catalytic activity

0.45	GO:0005622	intracellular
0.44	GO:0043209	myelin sheath
0.41	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.37	GO:0098796	membrane protein complex
0.36	GO:0098793	presynapse
0.34	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q9U6Y9|ANM5_DROME
Protein arginine N-methyltransferase 5
Search

0.65	Protein arginine N-methyltransferase

0.84	GO:0035246	peptidyl-arginine N-methylation
0.57	GO:0007318	pole plasm protein localization
0.57	GO:0030719	P granule organization
0.55	GO:0035076	ecdysone receptor-mediated signaling pathway
0.54	GO:0008298	intracellular mRNA localization
0.54	GO:0034969	histone arginine methylation
0.51	GO:0040007	growth
0.47	GO:1903359	lateral cortical node assembly
0.47	GO:1903360	protein localization to lateral cortical node
0.47	GO:0061246	establishment or maintenance of bipolar cell polarity regulating cell shape

0.63	GO:0008168	methyltransferase activity
0.46	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0016301	kinase activity
0.33	GO:0010181	FMN binding
0.32	GO:0004003	ATP-dependent DNA helicase activity
0.32	GO:0016491	oxidoreductase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0003677	DNA binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005634	nucleus
0.47	GO:1990463	lateral cortical node
0.46	GO:0071521	Cdc42 GTPase complex
0.46	GO:0005829	cytosol
0.44	GO:0051286	cell tip
0.30	GO:0016020	membrane

0.63

GO:0008168

tr|Q9U721|Q9U721_DROME
Allatostatin A receptor 1, isoform B
Search

0.71	A-type allatostatin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0009755	hormone-mediated signaling pathway
0.36	GO:0006468	protein phosphorylation

0.72	GO:0004930	G-protein coupled receptor activity
0.54	GO:0001653	peptide receptor activity
0.40	GO:0050254	rhodopsin kinase activity
0.35	GO:0042923	neuropeptide binding
0.35	GO:0042562	hormone binding

0.45

GO:0005887

integral component of plasma membrane

0.40

EC:2.7.11.14

GO:0050254

tr|Q9U8L5|Q9U8L5_DROME
Dorsocross1, isoform A
Search

0.76	T-box transcription factor TBX6

0.63	GO:0061327	anterior Malpighian tubule development
0.59	GO:0035051	cardiocyte differentiation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0035294	determination of wing disc primordium
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.51	GO:0001700	embryonic development via the syncytial blastoderm
0.34	GO:0072045	convergent extension involved in nephron morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9U915|KAD2_DROME
Adenylate kinase
Search

ADK2

0.46	Adenylate kinase

0.83	GO:0006172	ADP biosynthetic process
0.69	GO:0046939	nucleotide phosphorylation
0.68	GO:0046033	AMP metabolic process
0.57	GO:0046034	ATP metabolic process
0.35	GO:0035172	hemocyte proliferation
0.34	GO:0060218	hematopoietic stem cell differentiation
0.34	GO:0015949	nucleobase-containing small molecule interconversion
0.34	GO:0016049	cell growth
0.34	GO:0002521	leukocyte differentiation

0.78	GO:0004017	adenylate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0005758	mitochondrial intermembrane space
0.62	GO:0005829	cytosol
0.43	GO:0097226	sperm mitochondrial sheath
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.34	GO:0070062	extracellular exosome

0.78

EC:2.7.4.3

GO:0004017

sp|Q9U969|SWS_DROME
Neuropathy target esterase sws
Search

0.77	Neuropathy target esterase sws

0.77	GO:0046470	phosphatidylcholine metabolic process
0.71	GO:0016042	lipid catabolic process
0.52	GO:0034349	glial cell apoptotic process
0.51	GO:2000480	negative regulation of cAMP-dependent protein kinase activity
0.51	GO:0051402	neuron apoptotic process
0.50	GO:0045494	photoreceptor cell maintenance
0.49	GO:0007272	ensheathment of neurons
0.46	GO:0007608	sensory perception of smell
0.45	GO:0006643	membrane lipid metabolic process
0.45	GO:0072657	protein localization to membrane

0.78	GO:0004622	lysophospholipase activity
0.50	GO:0034236	protein kinase A catalytic subunit binding

0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:3.1.1.5

GO:0004622

sp|Q9U9P7|PITC1_DROME
Cytoplasmic phosphatidylinositol transfer protein 1
Search

0.79	Cytoplasmic phosphatidylinositol transfer protein 1

0.79	GO:0015914	phospholipid transport
0.36	GO:0007165	signal transduction
0.33	GO:0046488	phosphatidylinositol metabolic process

0.80	GO:0005548	phospholipid transporter activity
0.41	GO:1901611	phosphatidylglycerol binding
0.40	GO:0070300	phosphatidic acid binding
0.38	GO:0035091	phosphatidylinositol binding
0.33	GO:0005515	protein binding
0.32	GO:0016740	transferase activity

0.45	GO:0005622	intracellular
0.37	GO:0043233	organelle lumen
0.35	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.32

GO:0016740

tr|Q9U9Q1|Q9U9Q1_DROME
Replication factor C 38kD subunit, isoform A
Search

RFC3

0.71	Replication factor C subunit

0.66	GO:0006260	DNA replication
0.52	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
0.50	GO:0046683	response to organophosphorus
0.41	GO:0006281	DNA repair
0.37	GO:0022616	DNA strand elongation
0.36	GO:0007062	sister chromatid cohesion
0.35	GO:0042769	DNA damage response, detection of DNA damage
0.34	GO:1901796	regulation of signal transduction by p53 class mediator
0.34	GO:0071897	DNA biosynthetic process
0.34	GO:0000723	telomere maintenance

0.54	GO:0003677	DNA binding
0.53	GO:0033170	protein-DNA loading ATPase activity
0.50	GO:0043142	single-stranded DNA-dependent ATPase activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0005515	protein binding

0.53	GO:0005663	DNA replication factor C complex
0.50	GO:0031390	Ctf18 RFC-like complex
0.48	GO:0031391	Elg1 RFC-like complex
0.40	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7.7

GO:0003887

tr|Q9U9Q2|Q9U9Q2_DROME
Neosin, isoform A
Search

0.58	nuclear receptor coactivator 5

0.41	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0019358	nicotinate nucleotide salvage
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0009435	NAD biosynthetic process
0.33	GO:0006351	transcription, DNA-templated

0.59	GO:0003723	RNA binding
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0004516	nicotinate phosphoribosyltransferase activity
0.34	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity

0.43	GO:0071011	precatalytic spliceosome
0.35	GO:0016592	mediator complex
0.34	GO:0005840	ribosome

0.35	EC:2.4.2.11	GO:0004516
0.35	KEGG:R01724	GO:0004516

sp|Q9U9Q4|EIF3H_DROME
Eukaryotic translation initiation factor 3 subunit H
Search

0.71	Eukaryotic translation initiation factor 3 subunit H

0.72	GO:0006413	translational initiation
0.69	GO:0002181	cytoplasmic translation
0.65	GO:0022618	ribonucleoprotein complex assembly
0.47	GO:0045747	positive regulation of Notch signaling pathway
0.33	GO:0006508	proteolysis

0.73	GO:0003743	translation initiation factor activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008233	peptidase activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.69	GO:0016282	eukaryotic 43S preinitiation complex
0.69	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0008233

sp|Q9UAS6|CMTR2_DROME
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2
Search

0.77	FtsJ methyltransferase domain-containing protein 1

0.63	GO:0032259	methylation
0.54	GO:0007424	open tracheal system development
0.47	GO:0016556	mRNA modification
0.47	GO:0006370	7-methylguanosine mRNA capping
0.37	GO:0035239	tube morphogenesis
0.37	GO:0016477	cell migration
0.37	GO:0044260	cellular macromolecule metabolic process

0.63	GO:0008168	methyltransferase activity
0.41	GO:0140098	catalytic activity, acting on RNA

0.47	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0008168

sp|Q9V333|KDM4A_DROME
Probable lysine-specific demethylase 4A
Search

0.81	JmjC domain-containing histone demethylation protein 3C

0.52	GO:0070544	histone H3-K36 demethylation
0.51	GO:0033169	histone H3-K9 demethylation
0.45	GO:0032259	methylation
0.43	GO:0010628	positive regulation of gene expression
0.35	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.34	GO:0006351	transcription, DNA-templated

0.52	GO:0051864	histone demethylase activity (H3-K36 specific)
0.51	GO:0032454	histone demethylase activity (H3-K9 specific)
0.45	GO:0008168	methyltransferase activity
0.40	GO:0046872	metal ion binding
0.38	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.47	GO:0000792	heterochromatin
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:1.14.11.27

GO:0051864

sp|Q9V345|CSN4_DROME
COP9 signalosome complex subunit 4
Search

COPS4

0.74	COP9 signalosome complex subunit

0.51	GO:0000338	protein deneddylation
0.48	GO:0048140	male germ-line cyst encapsulation
0.47	GO:0036099	female germ-line stem cell population maintenance
0.46	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.46	GO:0001751	compound eye photoreceptor cell differentiation
0.44	GO:0050821	protein stabilization
0.44	GO:0007281	germ cell development
0.37	GO:0098656	anion transmembrane transport
0.35	GO:0007292	female gamete generation
0.34	GO:0043687	post-translational protein modification

0.52	GO:0019784	NEDD8-specific protease activity
0.43	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0008308	voltage-gated anion channel activity
0.35	GO:0005515	protein binding

0.81	GO:0008180	COP9 signalosome
0.42	GO:0008021	synaptic vesicle
0.41	GO:0005829	cytosol
0.40	GO:0030054	cell junction
0.38	GO:0005741	mitochondrial outer membrane
0.36	GO:0016607	nuclear speck
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q9V359|VPS28_DROME
Vacuolar protein sorting-associated protein 28 homolog
Search

0.86	Vacuolar protein sorting-associated protein 28 homolog

0.81	GO:0032509	endosome transport via multivesicular body sorting pathway
0.80	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.79	GO:0045324	late endosome to vacuole transport
0.79	GO:0072666	establishment of protein localization to vacuole
0.66	GO:0006886	intracellular protein transport
0.47	GO:0010796	regulation of multivesicular body size
0.47	GO:0044130	negative regulation of growth of symbiont in host
0.47	GO:0007291	sperm individualization
0.46	GO:0016322	neuron remodeling
0.46	GO:0097352	autophagosome maturation

0.41	GO:0043130	ubiquitin binding
0.40	GO:0032403	protein complex binding

0.82	GO:0000813	ESCRT I complex
0.41	GO:0005769	early endosome
0.38	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|Q9V392|Q9V392_DROME
FI01909p
Search

0.10	multiple epidermal growth factor-like domains protein 11

0.80	GO:0043652	engulfment of apoptotic cell
0.35	GO:0006910	phagocytosis, recognition
0.35	GO:0050766	positive regulation of phagocytosis
0.35	GO:0010811	positive regulation of cell-substrate adhesion
0.35	GO:0050830	defense response to Gram-positive bacterium
0.34	GO:0006955	immune response
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0010952	positive regulation of peptidase activity
0.34	GO:0030198	extracellular matrix organization
0.32	GO:0055114	oxidation-reduction process

0.78	GO:0001786	phosphatidylserine binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0005201	extracellular matrix structural constituent
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0042834	peptidoglycan binding
0.34	GO:0016504	peptidase activator activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0004497	monooxygenase activity
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.51	GO:0005886	plasma membrane
0.35	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.34

GO:0016705

tr|Q9V393|Q9V393_DROME
Kurtz arrestin
Search

0.65	Kurtz arrestin

0.61	GO:0007165	signal transduction
0.52	GO:0060189	positive regulation of protein desumoylation
0.50	GO:0045614	negative regulation of plasmatocyte differentiation
0.50	GO:0035203	regulation of lamellocyte differentiation
0.50	GO:0045751	negative regulation of Toll signaling pathway
0.49	GO:0035641	locomotory exploration behavior
0.49	GO:0002168	instar larval development
0.48	GO:0061099	negative regulation of protein tyrosine kinase activity
0.48	GO:0045746	negative regulation of Notch signaling pathway
0.48	GO:0048581	negative regulation of post-embryonic development

0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0016301	kinase activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q9V395|Q9V395_DROME
BcDNA.LD28419
Search

0.38	Tetracycline resistance

0.55	GO:0055085	transmembrane transport
0.47	GO:0015904	tetracycline transport
0.47	GO:0043252	sodium-independent organic anion transport
0.46	GO:0048477	oogenesis
0.40	GO:0016578	histone deubiquitination
0.38	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0006915	apoptotic process

0.52	GO:0005215	transporter activity
0.39	GO:0003713	transcription coactivator activity
0.36	GO:0008270	zinc ion binding

0.50	GO:0031526	brush border membrane
0.43	GO:0030659	cytoplasmic vesicle membrane
0.40	GO:0071819	DUBm complex
0.39	GO:0000124	SAGA complex
0.36	GO:0032040	small-subunit processome
0.30	GO:0016021	integral component of membrane

tr|Q9V396|Q9V396_DROME
Carbonic anhydrase 1
Search

0.40	Eukaryotic-type carbonic anhydrase

0.72	GO:0006730	one-carbon metabolic process
0.43	GO:0044070	regulation of anion transport
0.42	GO:0032849	positive regulation of cellular pH reduction
0.42	GO:0038166	angiotensin-activated signaling pathway
0.42	GO:2000878	positive regulation of oligopeptide transport
0.42	GO:2001148	regulation of dipeptide transmembrane transport
0.42	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.41	GO:0015670	carbon dioxide transport
0.40	GO:0034764	positive regulation of transmembrane transport
0.39	GO:0002009	morphogenesis of an epithelium

0.78	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding
0.42	GO:0004064	arylesterase activity
0.32	GO:0005515	protein binding

0.41	GO:0045177	apical part of cell
0.40	GO:0043209	myelin sheath
0.38	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.35	GO:0005902	microvillus
0.35	GO:0030424	axon
0.34	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.78

EC:4.2.1.1

GO:0004089

tr|Q9V397|Q9V397_DROME
BcDNA.GH12558
Search

0.41	Fatty acid oxidation complex subunit alpha

0.75	GO:0006635	fatty acid beta-oxidation
0.47	GO:0008340	determination of adult lifespan
0.45	GO:0042060	wound healing
0.45	GO:0042594	response to starvation
0.35	GO:0032868	response to insulin
0.33	GO:0042493	response to drug
0.32	GO:0055085	transmembrane transport

0.76	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.76	GO:0004300	enoyl-CoA hydratase activity
0.35	GO:0016508	long-chain-enoyl-CoA hydratase activity
0.34	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0003988	acetyl-CoA C-acyltransferase activity
0.34	GO:0051287	NAD binding
0.33	GO:0032403	protein complex binding
0.33	GO:0016853	isomerase activity

0.85	GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex
0.44	GO:0005777	peroxisome
0.35	GO:0042645	mitochondrial nucleoid
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.33	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:1.1.1.35

GO:0003857

sp|Q9V399|CP303_DROME
Probable cytochrome P450 303a1
Search

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0007423	sensory organ development
0.33	GO:0044550	secondary metabolite biosynthetic process
0.33	GO:0006696	ergosterol biosynthetic process
0.33	GO:0099120	socially cooperative development
0.32	GO:0032259	methylation

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.63	GO:0020037	heme binding
0.63	GO:0004497	monooxygenase activity
0.63	GO:0005506	iron ion binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.36	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|Q9V3A0|Q9V3A0_DROME
CG8997 protein
Search

0.30	Hemolymph juvenile hormone binding protein (JHBP)

0.46

GO:0016310

phosphorylation

0.56	GO:0008289	lipid binding
0.48	GO:0016301	kinase activity

tr|Q9V3A3|Q9V3A3_DROME
CG11379-PA
Search

0.30

GO:0044425

membrane part

sp|Q9V3A4|CSUP_DROME
Protein catecholamines up
Search

0.48	Zinc transporter

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.50	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.50	GO:0010312	detoxification of zinc ion
0.49	GO:0042069	regulation of catecholamine metabolic process
0.48	GO:0007298	border follicle cell migration
0.42	GO:0050790	regulation of catalytic activity
0.40	GO:0006882	cellular zinc ion homeostasis
0.38	GO:0072511	divalent inorganic cation transport
0.36	GO:0007300	ovarian nurse cell to oocyte transport

0.69	GO:0046873	metal ion transmembrane transporter activity
0.43	GO:0030234	enzyme regulator activity
0.39	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0097038	perinuclear endoplasmic reticulum
0.46	GO:0008021	synaptic vesicle
0.46	GO:0043025	neuronal cell body
0.46	GO:0030424	axon
0.34	GO:0030904	retromer complex
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q9V3A6|ERO1L_DROME
Ero1-like protein
Search

0.73	Endoplasmic reticulum oxidoreduction 1

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0034975	protein folding in endoplasmic reticulum
0.48	GO:0008593	regulation of Notch signaling pathway
0.42	GO:0022417	protein maturation by protein folding
0.42	GO:0019471	4-hydroxyproline metabolic process
0.42	GO:0051085	chaperone cofactor-dependent protein refolding
0.42	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.41	GO:0051209	release of sequestered calcium ion into cytosol
0.41	GO:0030968	endoplasmic reticulum unfolded protein response
0.40	GO:0030198	extracellular matrix organization

0.83	GO:0003756	protein disulfide isomerase activity
0.76	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.41	GO:0015035	protein disulfide oxidoreductase activity
0.35	GO:0016301	kinase activity

0.70	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.35	GO:0030425	dendrite
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:5.3.4.1

GO:0003756

tr|Q9V3A7|Q9V3A7_DROME
Structural maintenance of chromosomes protein
Search

0.10	Putative structural maintenance of chromosome protein 2 chromosome condensation complex condensin (Fragment)

0.66	GO:0051276	chromosome organization
0.50	GO:0140014	mitotic nuclear division
0.50	GO:0051304	chromosome separation
0.49	GO:0098813	nuclear chromosome segregation
0.43	GO:0007419	ventral cord development
0.42	GO:0007422	peripheral nervous system development
0.34	GO:0140013	meiotic nuclear division
0.33	GO:0071822	protein complex subunit organization
0.32	GO:0055085	transmembrane transport

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003682	chromatin binding
0.40	GO:0046982	protein heterodimerization activity
0.37	GO:0016887	ATPase activity
0.36	GO:0003677	DNA binding

0.67	GO:0005694	chromosome
0.57	GO:0005634	nucleus
0.48	GO:0044815	DNA packaging complex
0.42	GO:0043234	protein complex
0.41	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016887

tr|Q9V3A8|Q9V3A8_DROME
Ergic53, isoform A
Search

0.48	Truncated ER mannose-binding lectin

0.74	GO:0006888	ER to Golgi vesicle-mediated transport
0.41	GO:0007030	Golgi organization
0.40	GO:0007029	endoplasmic reticulum organization
0.40	GO:0010638	positive regulation of organelle organization
0.35	GO:0030001	metal ion transport
0.34	GO:0042256	mature ribosome assembly
0.34	GO:0034498	early endosome to Golgi transport
0.34	GO:0042273	ribosomal large subunit biogenesis
0.34	GO:0032527	protein exit from endoplasmic reticulum
0.34	GO:0055085	transmembrane transport

0.82	GO:0005537	mannose binding
0.35	GO:0046873	metal ion transmembrane transporter activity
0.34	GO:0043023	ribosomal large subunit binding
0.34	GO:0043022	ribosome binding
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0051082	unfolded protein binding
0.32	GO:0046872	metal ion binding
0.32	GO:0032555	purine ribonucleotide binding

0.47	GO:0005737	cytoplasm
0.41	GO:0044220	host cell perinuclear region of cytoplasm
0.38	GO:0097708	intracellular vesicle
0.38	GO:0099512	supramolecular fiber
0.38	GO:0012505	endomembrane system
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044422	organelle part
0.36	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0070062	extracellular exosome

tr|Q9V3A9|Q9V3A9_DROME
CG4218, isoform A
Search

tr|Q9V3B1|Q9V3B1_DROME
AT09889p
Search

sp|Q9V3B4|FADD_DROME
Fas-associated death domain protein
Search

0.73	Death domain-containing adapter protein BG4

0.82	GO:0061057	peptidoglycan recognition protein signaling pathway
0.80	GO:0007291	sperm individualization
0.79	GO:0002230	positive regulation of defense response to virus by host
0.77	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.75	GO:0050829	defense response to Gram-negative bacterium
0.70	GO:0006915	apoptotic process
0.67	GO:0006955	immune response
0.47	GO:0006963	positive regulation of antibacterial peptide biosynthetic process
0.44	GO:0045089	positive regulation of innate immune response

0.82

GO:0050700

CARD domain binding

0.46

GO:0005737

cytoplasm

tr|Q9V3B5|Q9V3B5_DROME
FI14826p
Search

0.39	Ubiquitin-conjugating enzyme variant

0.43	GO:0016567	protein ubiquitination
0.35	GO:0006301	postreplication repair
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.45	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0080132	fatty acid alpha-hydroxylase activity
0.33	GO:0003735	structural constituent of ribosome

0.39	GO:0005783	endoplasmic reticulum
0.35	GO:0005654	nucleoplasm
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V3B6|CWC15_DROME
Protein CWC15 homolog
Search

0.62	CWC15 spliceosome-associated protein homolog (S. cerevisiae)

0.75

GO:0000398

mRNA splicing, via spliceosome

0.36

GO:0003723

RNA binding

0.76	GO:0005681	spliceosomal complex
0.43	GO:0016607	nuclear speck
0.39	GO:1902494	catalytic complex
0.38	GO:0005739	mitochondrion

tr|Q9V3B8|Q9V3B8_DROME
LD18634p
Search

0.63	insulinoma-associated protein 1

0.51	GO:0007411	axon guidance
0.50	GO:0045666	positive regulation of neuron differentiation
0.40	GO:0031536	positive regulation of exit from mitosis
0.40	GO:0055057	neuroblast division
0.39	GO:0001764	neuron migration
0.39	GO:0045165	cell fate commitment
0.39	GO:0060290	transdifferentiation
0.38	GO:0003310	pancreatic A cell differentiation
0.38	GO:0003309	type B pancreatic cell differentiation
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.39	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0003682	chromatin binding
0.36	GO:0042826	histone deacetylase binding
0.35	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0030332	cyclin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0003714	transcription corepressor activity

0.38	GO:0005634	nucleus
0.37	GO:0017053	transcriptional repressor complex
0.32	GO:0005737	cytoplasm

sp|Q9V3C0|DDX41_DROME
ATP-dependent RNA helicase abstrakt
Search

0.41	ATP-dependent RNA helicase abstrakt

0.41	GO:0010501	RNA secondary structure unwinding
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006334	nucleosome assembly
0.33	GO:0006468	protein phosphorylation

0.59	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.50	GO:0008270	zinc ion binding
0.40	GO:0008186	RNA-dependent ATPase activity
0.37	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0004672	protein kinase activity

0.41	GO:0071013	catalytic step 2 spliceosome
0.39	GO:0005730	nucleolus
0.35	GO:0071011	precatalytic spliceosome
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V3C1|VHL_DROME
Protein Vhl
Search

0.85	Putative e3 ubiquitin ligase vhl component von hippel-lindau tumor suppressor in s

0.86	GO:0035149	lumen formation, open tracheal system
0.86	GO:0007427	epithelial cell migration, open tracheal system
0.86	GO:0016334	establishment or maintenance of polarity of follicular epithelium
0.86	GO:1900037	regulation of cellular response to hypoxia
0.85	GO:0060438	trachea development
0.85	GO:0007026	negative regulation of microtubule depolymerization
0.85	GO:0006611	protein export from nucleus
0.84	GO:0090307	mitotic spindle assembly
0.82	GO:0007098	centrosome cycle
0.72	GO:0016567	protein ubiquitination

0.73	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0005515	protein binding
0.36	GO:0016874	ligase activity

0.87

GO:0030891

VCB complex

0.36	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

tr|Q9V3C2|Q9V3C2_DROME
LD47384p
Search

0.44	Vacuolar protein sorting-associated protein 21

0.49	GO:0007422	peripheral nervous system development
0.37	GO:0032482	Rab protein signal transduction
0.36	GO:0042546	cell wall biogenesis
0.36	GO:1903024	positive regulation of ascospore-type prospore membrane assembly
0.36	GO:1990896	protein localization to cell cortex of cell tip
0.35	GO:1902441	protein localization to meiotic spindle pole body
0.35	GO:0016192	vesicle-mediated transport
0.35	GO:0045921	positive regulation of exocytosis
0.35	GO:0042144	vacuole fusion, non-autophagic
0.35	GO:0000281	mitotic cytokinesis

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0071949	FAD binding
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0046872	metal ion binding

0.43	GO:0005768	endosome
0.39	GO:0005794	Golgi apparatus
0.39	GO:0009504	cell plate
0.35	GO:0090619	meiotic spindle pole
0.35	GO:0090726	cortical dynamic polarity patch
0.35	GO:0005628	prospore membrane
0.35	GO:0045202	synapse
0.35	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0030139	endocytic vesicle

0.32

GO:0004222

tr|Q9V3C4|Q9V3C4_DROME
BcDNA.LD05563
Search

0.54	GO:0007629	flight behavior
0.52	GO:0007528	neuromuscular junction development
0.47	GO:0022618	ribonucleoprotein complex assembly
0.45	GO:0010501	RNA secondary structure unwinding
0.43	GO:0016973	poly(A)+ mRNA export from nucleus
0.43	GO:0009737	response to abscisic acid
0.42	GO:0009409	response to cold
0.41	GO:0009408	response to heat
0.40	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0050810	regulation of steroid biosynthetic process

0.55	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0008186	RNA-dependent ATPase activity
0.39	GO:0140098	catalytic activity, acting on RNA
0.37	GO:0016779	nucleotidyltransferase activity
0.34	GO:0070491	repressing transcription factor binding
0.34	GO:0042826	histone deacetylase binding

0.54	GO:0071254	cytoplasmic U snRNP body
0.53	GO:0032797	SMN complex
0.52	GO:0015030	Cajal body
0.42	GO:0005730	nucleolus
0.41	GO:0005635	nuclear envelope
0.36	GO:0005886	plasma membrane
0.34	GO:0034719	SMN-Sm protein complex
0.34	GO:0090571	RNA polymerase II transcription repressor complex
0.33	GO:0035098	ESC/E(Z) complex
0.33	GO:0005829	cytosol

0.37

GO:0016779

sp|Q9V3C5|RIC1_DROME
Guanine nucleotide exchange factor subunit Rich
Search

0.94	Guanine nucleotide exchange factor subunit Rich

0.75	GO:0045467	R7 cell development
0.74	GO:0032483	regulation of Rab protein signal transduction
0.73	GO:0043087	regulation of GTPase activity
0.72	GO:0035418	protein localization to synapse
0.67	GO:0050808	synapse organization
0.66	GO:0007411	axon guidance
0.66	GO:0060078	regulation of postsynaptic membrane potential
0.65	GO:0051345	positive regulation of hydrolase activity
0.54	GO:0042147	retrograde transport, endosome to Golgi
0.52	GO:1903363	negative regulation of cellular protein catabolic process

0.72	GO:0017137	Rab GTPase binding
0.52	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.64	GO:0005794	Golgi apparatus
0.60	GO:0031410	cytoplasmic vesicle
0.56	GO:0032045	guanyl-nucleotide exchange factor complex
0.48	GO:0005829	cytosol
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|Q9V3C6|Q9V3C6_DROME
EG:BACR42I17.10 protein
Search

0.13

hornerin

0.45	GO:0006351	transcription, DNA-templated
0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.41	GO:0006468	protein phosphorylation
0.40	GO:0006508	proteolysis

0.48	GO:0005544	calcium-dependent phospholipid binding
0.47	GO:0003700	DNA binding transcription factor activity
0.46	GO:0003779	actin binding
0.44	GO:0005509	calcium ion binding
0.44	GO:0003677	DNA binding
0.44	GO:0004180	carboxypeptidase activity
0.43	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.43

GO:0004674

tr|Q9V3C8|Q9V3C8_DROME
DShc protein
Search

0.76	Adaptor protein SHC

0.62	GO:0035556	intracellular signal transduction
0.57	GO:0007426	tracheal outgrowth, open tracheal system
0.57	GO:0008293	torso signaling pathway
0.57	GO:0035011	melanotic encapsulation of foreign target
0.55	GO:0007173	epidermal growth factor receptor signaling pathway
0.47	GO:0000187	activation of MAPK activity
0.36	GO:0001525	angiogenesis
0.36	GO:0006383	transcription by RNA polymerase III
0.35	GO:0048863	stem cell differentiation
0.35	GO:0008284	positive regulation of cell proliferation

0.52	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0008484	sulfuric ester hydrolase activity
0.32	GO:0003723	RNA binding

0.45	GO:0005622	intracellular
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.7.6

GO:0003899

tr|Q9V3D0|Q9V3D0_DROME
LD33485p
Search

0.40	Mitogen-activated protein kinase kinase kinase kinase

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.33	GO:0043624	cellular protein complex disassembly
0.33	GO:0042254	ribosome biogenesis
0.32	GO:0016070	RNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.61	GO:0005840	ribosome
0.43	GO:0005759	mitochondrial matrix
0.42	GO:0044445	cytosolic part
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.33	GO:0005730	nucleolus
0.33	GO:0009507	chloroplast

sp|Q9V3D2|HEM6_DROME
Oxygen-dependent coproporphyrinogen-III oxidase
Search

0.41	Oxygen-dependent coproporphyrinogen-III oxidase

0.71	GO:0006779	porphyrin-containing compound biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0042168	heme metabolic process
0.41	GO:0046148	pigment biosynthetic process
0.36	GO:0006397	mRNA processing
0.35	GO:0046501	protoporphyrinogen IX metabolic process
0.35	GO:0010288	response to lead ion
0.35	GO:0042541	hemoglobin biosynthetic process
0.35	GO:0051597	response to methylmercury
0.35	GO:0017085	response to insecticide

0.78	GO:0004109	coproporphyrinogen oxidase activity
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0005212	structural constituent of eye lens
0.34	GO:0003723	RNA binding
0.34	GO:0003909	DNA ligase activity

0.41	GO:0005829	cytosol
0.36	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0031970	organelle envelope lumen
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.78	EC:1.3.3.3	GO:0004109
0.78	KEGG:R03220	GO:0004109

sp|Q9V3D4|IDGF2_DROME
Chitinase-like protein Idgf2
Search

0.38	Glycosyl hydrolase

0.61	GO:0018990	ecdysis, chitin-based cuticle
0.60	GO:0005975	carbohydrate metabolic process
0.60	GO:0040003	chitin-based cuticle development
0.59	GO:0007444	imaginal disc development
0.56	GO:0042060	wound healing
0.46	GO:0008284	positive regulation of cell proliferation
0.45	GO:0043066	negative regulation of apoptotic process
0.40	GO:0006032	chitin catabolic process
0.35	GO:0006034	cuticle chitin metabolic process

0.76	GO:0008061	chitin binding
0.66	GO:0008084	imaginal disc growth factor receptor binding
0.57	GO:0004568	chitinase activity

0.47	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.57

GO:0004568

sp|Q9V3D5|DYRK2_DROME
Dual specificity tyrosine-phosphorylation-regulated kinase 2
Search

0.52	Dual specificity tyrosine-phosphorylation-regulated kinase

0.63	GO:0006468	protein phosphorylation
0.37	GO:0042048	olfactory behavior
0.37	GO:0030177	positive regulation of Wnt signaling pathway
0.36	GO:0009416	response to light stimulus
0.36	GO:0007608	sensory perception of smell
0.36	GO:0018212	peptidyl-tyrosine modification

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q9V3D6|CPSF2_DROME
Probable cleavage and polyadenylation specificity factor subunit 2
Search

0.69	Cleavage and polyadenylation specificity factor subunit

0.81	GO:0006379	mRNA cleavage
0.81	GO:0006378	mRNA polyadenylation
0.56	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0051028	mRNA transport
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006405	RNA export from nucleus

0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0004527	exonuclease activity

0.83	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.30	GO:0016020	membrane

tr|Q9V3D7|Q9V3D7_DROME
CG3713, isoform A
Search

tr|Q9V3D9|Q9V3D9_DROME
Signal recognition particle 54 kDa protein
Search

SRP54

0.62	Signal recognition particle 54 kDa protein (Fragment)

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0090114	COPII-coated vesicle budding
0.34	GO:0046146	tetrahydrobiopterin metabolic process
0.34	GO:0034312	diol biosynthetic process
0.33	GO:0042559	pteridine-containing compound biosynthetic process
0.33	GO:0009108	coenzyme biosynthetic process
0.33	GO:0006396	RNA processing
0.33	GO:0006508	proteolysis

0.78	GO:0008312	7S RNA binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0030942	endoplasmic reticulum signal peptide binding
0.34	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0017110	nucleoside-diphosphatase activity

0.80	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.34	GO:0030127	COPII vesicle coat
0.33	GO:0000139	Golgi membrane
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:4.2.1.96	GO:0008124
0.34	KEGG:R04734	GO:0008124

tr|Q9V3E0|Q9V3E0_DROME
CG3706
Search

0.11	C-X-C chemokine receptor type 7

0.30

GO:0044425

membrane part

tr|Q9V3E3|Q9V3E3_DROME
GM06185p
Search

0.91	Mitochondrial ribosomal protein L50

0.37

GO:0032543

mitochondrial translation

0.37	GO:0008270	zinc ion binding
0.35	GO:0003676	nucleic acid binding
0.35	GO:0003735	structural constituent of ribosome

0.57	GO:0005739	mitochondrion
0.51	GO:0005840	ribosome
0.37	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V3E4|Q9V3E4_DROME
EG:BACR42I17.3 protein
Search

0.37

GO:0006491

N-glycan processing

0.39

GO:0016740

transferase activity

0.33	GO:0043229	intracellular organelle
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016740

tr|Q9V3E5|Q9V3E5_DROME
Tetraspanin
Search

0.64	Tetraspanin

0.38	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0007283	spermatogenesis
0.32	GO:0060255	regulation of macromolecule metabolic process

0.46	GO:0005886	plasma membrane
0.34	GO:0009986	cell surface
0.30	GO:0044425	membrane part

tr|Q9V3E7|Q9V3E7_DROME
LD24793p
Search

ALYREF

0.71	RNA and export factor-binding protein 2

0.38	GO:0008380	RNA splicing
0.38	GO:0006397	mRNA processing
0.37	GO:0051028	mRNA transport
0.35	GO:0050790	regulation of catalytic activity

0.59	GO:0003723	RNA binding
0.37	GO:0005094	Rho GDP-dissociation inhibitor activity
0.33	GO:0003697	single-stranded DNA binding

0.48	GO:0031965	nuclear membrane
0.47	GO:0005654	nucleoplasm
0.37	GO:0005681	spliceosomal complex
0.36	GO:0000346	transcription export complex
0.34	GO:0005737	cytoplasm
0.34	GO:1902494	catalytic complex

tr|Q9V3E9|Q9V3E9_DROME
FI17138p1
Search

0.45	LOW QUALITY PROTEIN: RNA polymerase II-associated protein 3

0.80	GO:1904059	regulation of locomotor rhythm
0.80	GO:2000672	negative regulation of motor neuron apoptotic process
0.55	GO:0016567	protein ubiquitination
0.53	GO:0090035	positive regulation of chaperone-mediated protein complex assembly
0.52	GO:0030579	ubiquitin-dependent SMAD protein catabolic process
0.52	GO:0031943	regulation of glucocorticoid metabolic process
0.50	GO:0071218	cellular response to misfolded protein
0.50	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.49	GO:0032091	negative regulation of protein binding
0.49	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process

0.62	GO:0051879	Hsp90 protein binding
0.61	GO:0030544	Hsp70 protein binding
0.56	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0030911	TPR domain binding
0.50	GO:0051787	misfolded protein binding
0.49	GO:0046332	SMAD binding
0.48	GO:0001664	G-protein coupled receptor binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0019900	kinase binding
0.47	GO:0061659	ubiquitin-like protein ligase activity

0.51	GO:0042405	nuclear inclusion body
0.49	GO:0030018	Z disc
0.46	GO:0000151	ubiquitin ligase complex
0.44	GO:0005829	cytosol
0.44	GO:0005783	endoplasmic reticulum
0.44	GO:0005654	nucleoplasm
0.36	GO:0031371	ubiquitin conjugating enzyme complex
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.40	EC:6	GO:0016874
0.56	KEGG:R03876	GO:0004842

tr|Q9V3F2|Q9V3F2_DROME
LD36009p
Search

0.66	Serine palmitoyltransferase

0.56	GO:0030148	sphingolipid biosynthetic process
0.54	GO:0006667	sphinganine metabolic process
0.53	GO:1904502	regulation of lipophagy
0.52	GO:0006670	sphingosine metabolic process
0.51	GO:0006684	sphingomyelin metabolic process
0.50	GO:0016239	positive regulation of macroautophagy
0.49	GO:0006672	ceramide metabolic process
0.49	GO:0034312	diol biosynthetic process
0.46	GO:0007444	imaginal disc development
0.44	GO:0008654	phospholipid biosynthetic process

0.67	GO:0030170	pyridoxal phosphate binding
0.59	GO:0004758	serine C-palmitoyltransferase activity
0.34	GO:0008483	transaminase activity

0.51	GO:0017059	serine C-palmitoyltransferase complex
0.41	GO:0005739	mitochondrion
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.59	EC:2.3.1.50	GO:0004758
0.59	KEGG:R01281	GO:0004758

sp|Q9V3F3|MTTF_DROME
Transcription termination factor, mitochondrial
Search

0.92	Transcription termination factor, mitochondrial

0.72	GO:0006393	termination of mitochondrial transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0006260	DNA replication
0.37	GO:0043461	proton-transporting ATP synthase complex assembly

0.72

GO:0003690

double-stranded DNA binding

0.50	GO:0005739	mitochondrion
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

tr|Q9V3F8|Q9V3F8_DROME
Pyrroline-5-carboxylate reductase
Search

0.47	Methionine aminopeptidase

0.75	GO:0006561	proline biosynthetic process
0.57	GO:0017144	drug metabolic process
0.53	GO:0055114	oxidation-reduction process
0.36	GO:1901032	negative regulation of response to reactive oxygen species
0.36	GO:2001039	negative regulation of cellular response to drug
0.35	GO:1903205	regulation of hydrogen peroxide-induced cell death
0.35	GO:1903202	negative regulation of oxidative stress-induced cell death
0.35	GO:0051881	regulation of mitochondrial membrane potential
0.34	GO:0034599	cellular response to oxidative stress
0.32	GO:0006351	transcription, DNA-templated

0.79	GO:0004735	pyrroline-5-carboxylate reductase activity
0.34	GO:0042802	identical protein binding
0.32	GO:0030170	pyridoxal phosphate binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.41	GO:0005737	cytoplasm
0.33	GO:0043231	intracellular membrane-bounded organelle

0.79

EC:1.5.1.2

GO:0004735

tr|Q9V3F9|Q9V3F9_DROME
BcDNA.LD28120
Search

0.45	Monocarboxylate transporter

0.54	GO:0055085	transmembrane transport
0.54	GO:0007281	germ cell development
0.40	GO:0035234	ectopic germ cell programmed cell death
0.40	GO:0015718	monocarboxylic acid transport
0.37	GO:0070327	thyroid hormone transport

0.40	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.37	GO:0015349	thyroid hormone transmembrane transporter activity

0.36

GO:0005887

integral component of plasma membrane

sp|Q9V3G1|RL8_DROME
60S ribosomal protein L8
Search

0.52	Ribosomal Protein L2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.45	GO:0008286	insulin receptor signaling pathway
0.44	GO:0048749	compound eye development
0.44	GO:0008361	regulation of cell size

0.64	GO:0003735	structural constituent of ribosome
0.42	GO:0003723	RNA binding
0.33	GO:0004386	helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.43	GO:0044446	intracellular organelle part
0.40	GO:0005694	chromosome
0.40	GO:0043233	organelle lumen
0.38	GO:0005634	nucleus
0.36	GO:0044445	cytosolic part
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V3G3|PPIE_DROME
Peptidyl-prolyl cis-trans isomerase E
Search

0.43	Peptidyl-prolyl cis-trans isomerase E

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.69	GO:0006457	protein folding
0.45	GO:0045070	positive regulation of viral genome replication
0.43	GO:0000398	mRNA splicing, via spliceosome
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006309	apoptotic DNA fragmentation
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.58	GO:0003723	RNA binding
0.35	GO:0016018	cyclosporin A binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004518	nuclease activity

0.46	GO:0000974	Prp19 complex
0.44	GO:0071007	U2-type catalytic step 2 spliceosome
0.42	GO:0016607	nuclear speck
0.40	GO:0005829	cytosol
0.35	GO:0071011	precatalytic spliceosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.33	GO:0005576	extracellular region
0.33	GO:0005739	mitochondrion

0.72

GO:0003755

sp|Q9V3G6|CNO10_DROME
CCR4-NOT transcription complex subunit 10
Search

0.66	CCR4-NOT transcription complex subunit 10

0.69	GO:0017148	negative regulation of translation
0.68	GO:0006402	mRNA catabolic process
0.45	GO:0031047	gene silencing by RNA
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006457	protein folding

0.48	GO:0042802	identical protein binding
0.44	GO:0016603	glutaminyl-peptide cyclotransferase activity
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.75	GO:0030014	CCR4-NOT complex
0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.44

EC:2.3.2.5

GO:0016603

sp|Q9V3G7|PSMD6_DROME
26S proteasome non-ATPase regulatory subunit 6
Search

0.66	26S proteasome non-ATPase regulatory subunit

0.69	GO:0050790	regulation of catalytic activity
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0008063	Toll signaling pathway
0.35	GO:0007623	circadian rhythm
0.35	GO:0070306	lens fiber cell differentiation
0.33	GO:0019441	tryptophan catabolic process to kynurenine
0.33	GO:0006869	lipid transport

0.70	GO:0030234	enzyme regulator activity
0.33	GO:0004061	arylformamidase activity
0.33	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.66	GO:1905369	endopeptidase complex
0.55	GO:0043234	protein complex
0.43	GO:0044424	intracellular part
0.33	GO:0043233	organelle lumen
0.33	GO:0043227	membrane-bounded organelle

0.33

EC:3.5.1.9

GO:0004061

tr|Q9V3G8|Q9V3G8_DROME
RH73259p
Search

0.54	Cell surface glycoprotein 1

0.30

GO:0044425

membrane part

tr|Q9V3G9|Q9V3G9_DROME
AT18705p
Search

0.12	Collagen-like protein 6

0.73

GO:0048515

spermatid differentiation

0.46

GO:0005581

collagen trimer

tr|Q9V3H0|Q9V3H0_DROME
DNAation factor-related protein 4
Search

0.83	DNAation factor subunit beta

0.86	GO:0006309	apoptotic DNA fragmentation
0.34	GO:0006364	rRNA processing
0.33	GO:0006520	cellular amino acid metabolic process
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0009058	biosynthetic process

0.51	GO:0016787	hydrolase activity
0.36	GO:0140097	catalytic activity, acting on DNA
0.35	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.34	GO:0070546	L-phenylalanine aminotransferase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.38	GO:0000785	chromatin
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0030688	preribosome, small subunit precursor
0.30	GO:0031224	intrinsic component of membrane

0.51	EC:3	GO:0016787
0.35	KEGG:R00355	GO:0004069

sp|Q9V3H2|PSDE_DROME
26S proteasome non-ATPase regulatory subunit 14
Search

0.44	Proteasome subunit alpha type

0.85	GO:0070536	protein K63-linked deubiquitination
0.48	GO:0010950	positive regulation of endopeptidase activity
0.47	GO:0006303	double-strand break repair via nonhomologous end joining
0.47	GO:0061136	regulation of proteasomal protein catabolic process
0.46	GO:0000724	double-strand break repair via homologous recombination
0.43	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:0001878	response to yeast
0.37	GO:0045471	response to ethanol
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0.85	GO:0061578	Lys63-specific deubiquitinase activity
0.50	GO:0061133	endopeptidase activator activity
0.48	GO:0070628	proteasome binding
0.46	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0008237	metallopeptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0004175	endopeptidase activity

0.66	GO:1905369	endopeptidase complex
0.54	GO:0043234	protein complex
0.42	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0048786	presynaptic active zone
0.33	GO:0012505	endomembrane system

0.46

EC:3.4.19.12

GO:0036459

tr|Q9V3H5|Q9V3H5_DROME
Cdk5 activator-like protein, isoform A
Search

0.68	Cyclin-dependent kinase 5 activator

0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.56	GO:0007411	axon guidance
0.53	GO:0035011	melanotic encapsulation of foreign target
0.52	GO:0021722	superior olivary nucleus maturation
0.52	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.52	GO:0042501	serine phosphorylation of STAT protein
0.51	GO:0008340	determination of adult lifespan
0.51	GO:0008344	adult locomotory behavior
0.51	GO:0007158	neuron cell-cell adhesion
0.51	GO:0021819	layer formation in cerebral cortex

0.86	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.50	GO:0035255	ionotropic glutamate receptor binding
0.49	GO:0016301	kinase activity
0.49	GO:0002020	protease binding
0.47	GO:0019901	protein kinase binding
0.46	GO:0051015	actin filament binding
0.38	GO:0045296	cadherin binding
0.38	GO:0046875	ephrin receptor binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0043014	alpha-tubulin binding

0.86	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.52	GO:0030426	growth cone
0.51	GO:0043025	neuronal cell body
0.51	GO:0030425	dendrite
0.51	GO:0030424	axon
0.47	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005654	nucleoplasm
0.38	GO:0044309	neuron spine
0.38	GO:0031594	neuromuscular junction
0.38	GO:0014069	postsynaptic density

0.32

GO:0016773

tr|Q9V3H6|Q9V3H6_DROME
CG7968
Search

tr|Q9V3H7|Q9V3H7_DROME
SR-CI
Search

SR-CI

0.96	Scavenger receptor CI

0.73	GO:0006955	immune response
0.71	GO:0006898	receptor-mediated endocytosis
0.59	GO:0050829	defense response to Gram-negative bacterium
0.59	GO:0006909	phagocytosis
0.33	GO:0006030	chitin metabolic process
0.32	GO:0000272	polysaccharide catabolic process
0.32	GO:0071390	cellular response to ecdysone
0.32	GO:1901072	glucosamine-containing compound catabolic process
0.32	GO:0006026	aminoglycan catabolic process
0.32	GO:0035335	peptidyl-tyrosine dephosphorylation

0.80	GO:0005044	scavenger receptor activity
0.77	GO:0001871	pattern binding
0.69	GO:0030246	carbohydrate binding
0.32	GO:0008061	chitin binding
0.32	GO:0004568	chitinase activity
0.32	GO:0005201	extracellular matrix structural constituent
0.32	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0005509	calcium ion binding

0.33	GO:0005576	extracellular region
0.33	GO:0005618	cell wall
0.32	GO:0031225	anchored component of membrane
0.32	GO:0051286	cell tip
0.31	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0004568

sp|Q9V3H8|NXT1_DROME
NTF2-related export protein
Search

0.80	Similar to Drosophila melanogaster Nxt1 (Fragment)

0.81	GO:0016973	poly(A)+ mRNA export from nucleus
0.47	GO:0050829	defense response to Gram-negative bacterium
0.44	GO:0045824	negative regulation of innate immune response
0.37	GO:0032259	methylation

0.37

GO:0008168

methyltransferase activity

0.74	GO:0005635	nuclear envelope
0.68	GO:0005654	nucleoplasm
0.48	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.37

GO:0008168

tr|Q9V3H9|Q9V3H9_DROME
BcDNA.LD27873
Search

0.10	zinc finger CCCH domain-containing protein 14

0.67	GO:1900364	negative regulation of mRNA polyadenylation
0.46	GO:0043488	regulation of mRNA stability
0.35	GO:0006397	mRNA processing
0.33	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.32	GO:0006334	nucleosome assembly
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.65	GO:1990825	sequence-specific mRNA binding
0.64	GO:0008143	poly(A) binding
0.53	GO:0046872	metal ion binding
0.34	GO:0051015	actin filament binding
0.32	GO:0003735	structural constituent of ribosome
0.31	GO:0003677	DNA binding

0.62	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.60	GO:0043005	neuron projection
0.50	GO:0005634	nucleus
0.43	GO:0036477	somatodendritic compartment
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0044446	intracellular organelle part
0.32	GO:0044815	DNA packaging complex
0.32	GO:0032993	protein-DNA complex

tr|Q9V3I0|Q9V3I0_DROME
EG:BACR42I17.2 protein
Search

P27K

0.42	27 kDa hemolymph protein (Fragment)

0.30

GO:0044425

membrane part

tr|Q9V3I1|Q9V3I1_DROME
BcDNA.LD08534
Search

DUT

0.40	deoxyuridine 5'-triphosphate nucleotidohydrolase

0.78	GO:0046080	dUTP metabolic process
0.43	GO:0009213	pyrimidine deoxyribonucleoside triphosphate catabolic process
0.43	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.40	GO:0006226	dUMP biosynthetic process
0.34	GO:0035863	dITP catabolic process
0.33	GO:1902476	chloride transmembrane transport
0.33	GO:0006281	DNA repair

0.80	GO:0004170	dUTP diphosphatase activity
0.43	GO:0042802	identical protein binding
0.38	GO:0000287	magnesium ion binding
0.34	GO:0035870	dITP diphosphatase activity
0.34	GO:0015377	cation:chloride symporter activity
0.34	GO:0003682	chromatin binding

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80	EC:3.6.1.23	GO:0004170
0.80	KEGG:R02100	GO:0004170

tr|Q9V3I2|Q9V3I2_DROME
Drab5
Search

0.64	Rab GTPase

0.52	GO:0060627	regulation of vesicle-mediated transport
0.51	GO:0099504	synaptic vesicle cycle
0.50	GO:0032386	regulation of intracellular transport
0.49	GO:0016197	endosomal transport
0.49	GO:0051050	positive regulation of transport
0.49	GO:0061883	clathrin-dependent endocytosis involved in vitellogenesis
0.48	GO:0046664	dorsal closure, amnioserosa morphology change
0.48	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway
0.48	GO:0048227	plasma membrane to endosome transport
0.48	GO:0051489	regulation of filopodium assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.47	GO:0019003	GDP binding
0.35	GO:0051021	GDP-dissociation inhibitor binding
0.32	GO:0046872	metal ion binding

0.53	GO:0005769	early endosome
0.50	GO:0098793	presynapse
0.48	GO:0030139	endocytic vesicle
0.47	GO:0010009	cytoplasmic side of endosome membrane
0.45	GO:0001726	ruffle
0.45	GO:0044306	neuron projection terminus
0.45	GO:0033267	axon part
0.45	GO:0036477	somatodendritic compartment
0.44	GO:0098857	membrane microdomain
0.43	GO:0005938	cell cortex

tr|Q9V3I3|Q9V3I3_DROME
FI03282p
Search

0.52	A-kinase anchor protein 10, mitochondrial

0.44	GO:0016310	phosphorylation
0.41	GO:0008104	protein localization
0.35	GO:0016539	intein-mediated protein splicing
0.33	GO:0007018	microtubule-based movement

0.83	GO:0051018	protein kinase A binding
0.46	GO:0016301	kinase activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.33	GO:0043234	protein complex
0.33	GO:0015630	microtubule cytoskeleton
0.33	GO:0044430	cytoskeletal part
0.32	GO:0005886	plasma membrane
0.32	GO:1902494	catalytic complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0008745

sp|Q9V3I5|JIL1_DROME
Chromosomal serine/threonine-protein kinase JIL-1
Search

JIL-1

0.37	Chromosomal serine/threonine-protein kinase JIL-1

0.63	GO:0006468	protein phosphorylation
0.56	GO:0018209	peptidyl-serine modification
0.55	GO:1902275	regulation of chromatin organization
0.55	GO:0035556	intracellular signal transduction
0.52	GO:0016570	histone modification
0.51	GO:0045893	positive regulation of transcription, DNA-templated
0.50	GO:0045815	positive regulation of gene expression, epigenetic
0.50	GO:0060969	negative regulation of gene silencing
0.49	GO:0070498	interleukin-1-mediated signaling pathway
0.49	GO:2000758	positive regulation of peptidyl-lysine acetylation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0000287	magnesium ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0035173	histone kinase activity
0.36	GO:0005515	protein binding
0.33	GO:0005057	signal transducer activity, downstream of receptor
0.32	GO:0003676	nucleic acid binding

0.54	GO:0016456	X chromosome located dosage compensation complex, transcription activating
0.52	GO:0005703	polytene chromosome puff
0.51	GO:0005705	polytene chromosome interband
0.49	GO:0031981	nuclear lumen
0.45	GO:0000785	chromatin
0.40	GO:0005829	cytosol
0.34	GO:0005840	ribosome

0.70

GO:0004674

tr|Q9V3I6|Q9V3I6_DROME
CG5861
Search

0.35	Seven transmembrane domain protein tMEM147

0.48	GO:0031648	protein destabilization
0.34	GO:0045727	positive regulation of translation
0.34	GO:0035235	ionotropic glutamate receptor signaling pathway
0.33	GO:0006006	glucose metabolic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0004970	ionotropic glutamate receptor activity
0.34	GO:0043022	ribosome binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0050661	NADP binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0051287	NAD binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005759	mitochondrial matrix
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:1.2.1

GO:0016620

sp|Q9V3I8|OGG1_DROME
N-glycosylase/DNA lyase
Search

OGG1

0.74	Mitochondrial N-glycosylase/DNA lyase

0.73	GO:0006284	base-excision repair
0.72	GO:0006289	nucleotide-excision repair
0.43	GO:0006979	response to oxidative stress
0.41	GO:1901291	negative regulation of double-strand break repair via single-strand annealing
0.41	GO:0070887	cellular response to chemical stimulus
0.40	GO:0033158	regulation of protein import into nucleus, translocation
0.38	GO:0009314	response to radiation
0.37	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.78	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.72	GO:0003684	damaged DNA binding
0.51	GO:0016829	lyase activity
0.38	GO:0008017	microtubule binding
0.35	GO:0004518	nuclease activity
0.32	GO:0046872	metal ion binding

0.39	GO:0016363	nuclear matrix
0.39	GO:0016607	nuclear speck
0.36	GO:0005739	mitochondrion
0.35	GO:0043234	protein complex
0.32	GO:0000775	chromosome, centromeric region
0.30	GO:0016020	membrane

0.78

EC:3.2.2.23

GO:0008534

tr|Q9V3I9|Q9V3I9_DROME
FI22161p1
Search

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0034249	negative regulation of cellular amide metabolic process
0.46	GO:0006401	RNA catabolic process
0.46	GO:0032269	negative regulation of cellular protein metabolic process
0.46	GO:0010558	negative regulation of macromolecule biosynthetic process
0.46	GO:0031327	negative regulation of cellular biosynthetic process
0.45	GO:0016071	mRNA metabolic process

0.43

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.51	GO:0030015	CCR4-NOT core complex
0.50	GO:0000932	P-body

sp|Q9V3J1|VATH_DROME
V-type proton ATPase subunit H
Search

0.74	Vacuolar ATP synthase subunit h

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.38	GO:0007035	vacuolar acidification
0.37	GO:0033227	dsRNA transport
0.36	GO:0008340	determination of adult lifespan

0.81

GO:0046961

proton-transporting ATPase activity, rotational mechanism

0.84	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain
0.37	GO:0005765	lysosomal membrane
0.37	GO:0033181	plasma membrane proton-transporting V-type ATPase complex

sp|Q9V3J3|MS57C_DROME
Accessory gland-specific peptide 57Dc
Search

0.26	Accessory gland-specific peptide 57Dc

0.88	GO:0045297	post-mating behavior
0.86	GO:0018991	oviposition

0.73

GO:0005615

extracellular space

sp|Q9V3J4|SEC13_DROME
Protein SEC13 homolog
Search

SEC13

0.66	Cleavage stimulation factor subunit

0.84	GO:1904263	positive regulation of TORC1 signaling
0.83	GO:0090114	COPII-coated vesicle budding
0.65	GO:0015031	protein transport
0.52	GO:0035077	ecdysone-mediated polytene chromosome puffing
0.50	GO:0035293	chitin-based larval cuticle pattern formation
0.48	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter
0.46	GO:0034605	cellular response to heat
0.46	GO:0035459	cargo loading into vesicle
0.46	GO:0034504	protein localization to nucleus
0.45	GO:0051668	localization within membrane

0.62	GO:0005198	structural molecule activity
0.45	GO:0003682	chromatin binding
0.42	GO:0042802	identical protein binding
0.33	GO:0005179	hormone activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0015078	hydrogen ion transmembrane transporter activity

0.80	GO:0030127	COPII vesicle coat
0.74	GO:0000139	Golgi membrane
0.53	GO:0035859	Seh1-associated complex
0.49	GO:0098687	chromosomal region
0.48	GO:0005700	polytene chromosome
0.47	GO:0005654	nucleoplasm
0.46	GO:0031080	nuclear pore outer ring
0.45	GO:0005765	lysosomal membrane
0.44	GO:0000785	chromatin
0.38	GO:0070971	endoplasmic reticulum exit site

tr|Q9V3J5|Q9V3J5_DROME
CG3690, isoform A
Search

0.37	synaptic vesicle glycoprotein 2B

0.55	GO:0055085	transmembrane transport
0.36	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0006629	lipid metabolic process
0.32	GO:0015711	organic anion transport

0.46	GO:0022857	transmembrane transporter activity
0.36	GO:0016298	lipase activity
0.35	GO:0005509	calcium ion binding

0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.1.1

GO:0016298

tr|Q9V3J7|Q9V3J7_DROME
EG:BACR7A4.3 protein
Search

0.11	trypsin alpha-3

0.63	GO:0016486	peptide hormone processing
0.51	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide
0.50	GO:0035813	regulation of renal sodium excretion
0.46	GO:0007565	female pregnancy
0.43	GO:0006898	receptor-mediated endocytosis
0.41	GO:0032504	multicellular organism reproduction
0.34	GO:1903779	regulation of cardiac conduction
0.34	GO:0006956	complement activation
0.34	GO:0030182	neuron differentiation
0.33	GO:0019953	sexual reproduction

0.69	GO:0004252	serine-type endopeptidase activity
0.46	GO:0005044	scavenger receptor activity
0.33	GO:0005509	calcium ion binding

0.46	GO:0016604	nuclear body
0.45	GO:0015629	actin cytoskeleton
0.45	GO:0009986	cell surface
0.40	GO:0005576	extracellular region
0.39	GO:0005886	plasma membrane
0.38	GO:0001669	acrosomal vesicle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|Q9V3J8|WDS_DROME
Protein will die slowly
Search

0.47	WD repeat-containing protein 5

0.74	GO:0051568	histone H3-K4 methylation
0.71	GO:0016573	histone acetylation
0.65	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.62	GO:0007482	haltere development
0.59	GO:0001501	skeletal system development
0.58	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0001654	eye development
0.54	GO:0006338	chromatin remodeling
0.54	GO:0060271	cilium assembly
0.42	GO:0031175	neuron projection development

0.72	GO:0004402	histone acetyltransferase activity
0.65	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.65	GO:0035064	methylated histone binding
0.44	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.36	GO:0003743	translation initiation factor activity
0.35	GO:0050660	flavin adenine dinucleotide binding

0.75	GO:0044666	MLL3/4 complex
0.75	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.72	GO:0048188	Set1C/COMPASS complex
0.65	GO:0044665	MLL1/2 complex
0.62	GO:0044545	NSL complex
0.56	GO:0036064	ciliary basal body
0.41	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.72

GO:0004402

tr|Q9V3J9|Q9V3J9_DROME
Down and out, isoform A
Search

DAO

0.92	Down and out, isoform A

0.53	GO:0042051	compound eye photoreceptor development
0.37	GO:0010629	negative regulation of gene expression

0.39

GO:0042826

histone deacetylase binding

0.54	GO:0005886	plasma membrane
0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|Q9V3K3|RUVB2_DROME
RuvB-like helicase 2
Search

0.66	RuvB-like helicase

0.70	GO:0032508	DNA duplex unwinding
0.66	GO:0016569	covalent chromatin modification
0.61	GO:0006281	DNA repair
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0018393	internal peptidyl-lysine acetylation
0.49	GO:0006338	chromatin remodeling
0.47	GO:0006310	DNA recombination

0.81	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.44	GO:0001094	TFIID-class transcription factor binding
0.44	GO:0003714	transcription corepressor activity
0.44	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.44	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.44	GO:0004402	histone acetyltransferase activity

0.83	GO:0097255	R2TP complex
0.79	GO:0035267	NuA4 histone acetyltransferase complex
0.79	GO:0031011	Ino80 complex
0.47	GO:0000812	Swr1 complex
0.45	GO:0035102	PRC1 complex
0.44	GO:0005719	nuclear euchromatin
0.43	GO:0071339	MLL1 complex
0.42	GO:0005813	centrosome
0.40	GO:0005829	cytosol
0.37	GO:0030529	intracellular ribonucleoprotein complex

0.81

EC:3.6.1

GO:0043141

tr|Q9V3K5|Q9V3K5_DROME
CG4691
Search

0.72	DNA polymerase zeta processivity subunit

tr|Q9V3K9|Q9V3K9_DROME
Carnitine palmitoyltransferase I
Search

0.82	Carnitine palmitoyltransferase I

0.48	GO:0045471	response to ethanol
0.46	GO:0042594	response to starvation
0.45	GO:0010038	response to metal ion
0.43	GO:0006979	response to oxidative stress

0.63	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0003676	nucleic acid binding

0.35	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:2.3

GO:0016746

tr|Q9V3L0|Q9V3L0_DROME
Bc10
Search

0.89	Bladder cancer associated protein log

0.50	GO:0030262	apoptotic nuclear changes
0.37	GO:0007049	cell cycle

0.32

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q9V3L1|NDST_DROME
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase
Search

0.93	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase

0.53	GO:0090098	positive regulation of decapentaplegic signaling pathway
0.52	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
0.52	GO:0007509	mesoderm migration involved in gastrulation
0.52	GO:0007427	epithelial cell migration, open tracheal system
0.52	GO:0045570	regulation of imaginal disc growth
0.51	GO:0007367	segment polarity determination
0.51	GO:0007474	imaginal disc-derived wing vein specification
0.51	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.50	GO:0048312	intracellular distribution of mitochondria
0.50	GO:0048488	synaptic vesicle endocytosis

0.85	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity
0.51	GO:0016787	hydrolase activity
0.35	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity

0.50	GO:0000137	Golgi cis cisterna
0.46	GO:0045202	synapse
0.44	GO:0005783	endoplasmic reticulum
0.35	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:2.8.2.8

GO:0015016

sp|Q9V3L6|NCBP2_DROME
Nuclear cap-binding protein subunit 2
Search

0.70	Nuclear cap-binding protein subunit 2-A

0.81	GO:0045292	mRNA cis splicing, via spliceosome
0.47	GO:0031047	gene silencing by RNA
0.45	GO:0045071	negative regulation of viral genome replication
0.44	GO:0031050	dsRNA fragmentation
0.44	GO:0016441	posttranscriptional gene silencing
0.42	GO:0048523	negative regulation of cellular process
0.42	GO:0006417	regulation of translation
0.42	GO:0010824	regulation of centrosome duplication
0.41	GO:0060271	cilium assembly
0.41	GO:0051248	negative regulation of protein metabolic process

0.82	GO:0000339	RNA cap binding
0.37	GO:0017069	snRNA binding
0.37	GO:0003729	mRNA binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005846	nuclear cap binding complex
0.60	GO:0005634	nucleus
0.42	GO:0036038	MKS complex
0.34	GO:0005845	mRNA cap binding complex
0.33	GO:0044446	intracellular organelle part
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005737	cytoplasm
0.33	GO:1902494	catalytic complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V3L7|Q9V3L7_DROME
GEO04710p1
Search

0.78	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

0.38

GO:0022904

respiratory electron transport chain

0.41	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V3L8|Q9V3L8_DROME
Ccp84Aa
Search

0.51	larval cuticle protein A2B

0.45	GO:0040003	chitin-based cuticle development
0.35	GO:0032504	multicellular organism reproduction
0.32	GO:0007218	neuropeptide signaling pathway

0.78

GO:0042302

structural constituent of cuticle

0.41	GO:0031012	extracellular matrix
0.35	GO:0005615	extracellular space
0.33	GO:0070701	mucus layer
0.30	GO:0016020	membrane

tr|Q9V3M2|Q9V3M2_DROME
Uncharacterized protein, isoform A
Search

FRA10AC1

0.97	Fragile site, folic acid type, rare, candidate 1

0.40

GO:0006508

proteolysis

0.43	GO:0004252	serine-type endopeptidase activity
0.41	GO:0005515	protein binding

0.43

GO:0005634

nucleus

0.43

GO:0004252

tr|Q9V3M3|Q9V3M3_DROME
Metalloendopeptidase
Search

0.59	Metalloendopeptidase

0.61	GO:0006508	proteolysis
0.34	GO:0018996	molting cycle, collagen and cuticulin-based cuticle

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding

0.30

GO:0031224

intrinsic component of membrane

0.70

GO:0004222

tr|Q9V3M9|Q9V3M9_DROME
GH16413p
Search

0.78	Testis specific tektin

0.84	GO:0060294	cilium movement involved in cell motility
0.79	GO:0030317	flagellated sperm motility
0.73	GO:0060271	cilium assembly

0.61

GO:0008017

microtubule binding

0.78	GO:0036126	sperm flagellum
0.63	GO:0005875	microtubule associated complex
0.58	GO:0005634	nucleus
0.49	GO:0005747	mitochondrial respiratory chain complex I
0.44	GO:0005874	microtubule

sp|Q9V3N1|SP27A_DROME
Serine protease inhibitor 27A
Search

0.56	Leukocyte elastase inhibitor A

0.61	GO:0035009	negative regulation of melanization defense response
0.60	GO:0002213	defense response to insect
0.59	GO:0035011	melanotic encapsulation of foreign target
0.58	GO:0048149	behavioral response to ethanol
0.57	GO:0008063	Toll signaling pathway
0.57	GO:0009950	dorsal/ventral axis specification
0.55	GO:0050832	defense response to fungus
0.53	GO:0009611	response to wounding
0.53	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0006508	proteolysis

0.54	GO:0004867	serine-type endopeptidase inhibitor activity
0.43	GO:0008233	peptidase activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0002020	protease binding
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0016740	transferase activity

0.73	GO:0005615	extracellular space
0.33	GO:0009986	cell surface
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.43

GO:0008233

sp|Q9V3N2|OR46B_DROME
Odorant receptor 46a, isoform B
Search

0.43	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.54	GO:0005886	plasma membrane
0.47	GO:0030425	dendrite
0.46	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V3N4|Q9V3N4_DROME
Huntingtin, isoform A
Search

0.86	GO:0033697	positive regulation of extent of heterochromatin assembly
0.84	GO:0008088	axo-dendritic transport
0.83	GO:0000132	establishment of mitotic spindle orientation
0.81	GO:0048489	synaptic vesicle transport
0.32	GO:0055085	transmembrane transport
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.31	GO:0044267	cellular protein metabolic process
0.31	GO:1901566	organonitrogen compound biosynthetic process
0.31	GO:0010467	gene expression

0.33	GO:0016887	ATPase activity
0.32	GO:0005524	ATP binding
0.32	GO:0003735	structural constituent of ribosome
0.31	GO:0003700	DNA binding transcription factor activity

0.75	GO:0043005	neuron projection
0.74	GO:0045202	synapse
0.49	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.33	GO:0043190	ATP-binding cassette (ABC) transporter complex
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.33

GO:0016887

tr|Q9V3N5|Q9V3N5_DROME
FI21292p1
Search

0.39	Aaa atpase

0.48	GO:0051013	microtubule severing
0.43	GO:0030163	protein catabolic process
0.41	GO:0051301	cell division
0.41	GO:0006508	proteolysis
0.33	GO:0072662	protein localization to peroxisome
0.33	GO:0043574	peroxisomal transport
0.33	GO:0072594	establishment of protein localization to organelle
0.33	GO:0006605	protein targeting

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0008568	microtubule-severing ATPase activity
0.44	GO:0004222	metalloendopeptidase activity
0.41	GO:0008270	zinc ion binding
0.39	GO:0008017	microtubule binding
0.34	GO:0004176	ATP-dependent peptidase activity
0.32	GO:0004252	serine-type endopeptidase activity

0.40	GO:0000922	spindle pole
0.39	GO:0005874	microtubule
0.38	GO:0005886	plasma membrane
0.37	GO:0005634	nucleus
0.34	GO:1905369	endopeptidase complex
0.34	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:3.6.4.3

GO:0008568

tr|Q9V3N6|Q9V3N6_DROME
Transmembrane 9 superfamily member
Search

0.54	Transmembrane 9 superfamily member

0.52	GO:0006909	phagocytosis
0.50	GO:0061060	negative regulation of peptidoglycan recognition protein signaling pathway
0.49	GO:0035010	encapsulation of foreign target
0.47	GO:0070863	positive regulation of protein exit from endoplasmic reticulum
0.47	GO:0050829	defense response to Gram-negative bacterium
0.46	GO:2000010	positive regulation of protein localization to cell surface
0.46	GO:0072659	protein localization to plasma membrane
0.45	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.45	GO:0051453	regulation of intracellular pH
0.44	GO:0001666	response to hypoxia

0.40	GO:0003917	DNA topoisomerase type I activity
0.36	GO:0003677	DNA binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.44	GO:0005769	early endosome
0.41	GO:0005794	Golgi apparatus
0.38	GO:0005886	plasma membrane
0.37	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.40

EC:5.99.1.2

GO:0003917

sp|Q9V3N8|THG1_DROME
Probable tRNA(His) guanylyltransferase
Search

0.73	tRNA(His) guanylyltransferase

0.68	GO:0006400	tRNA modification
0.48	GO:0051289	protein homotetramerization
0.35	GO:0070932	histone H3 deacetylation
0.35	GO:0048015	phosphatidylinositol-mediated signaling
0.34	GO:0046854	phosphatidylinositol phosphorylation
0.34	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.34	GO:0006754	ATP biosynthetic process
0.34	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0006355	regulation of transcription, DNA-templated

0.85	GO:0008193	tRNA guanylyltransferase activity
0.64	GO:0000287	magnesium ion binding
0.61	GO:0032550	purine ribonucleoside binding
0.61	GO:0019001	guanyl nucleotide binding
0.51	GO:0032555	purine ribonucleotide binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042802	identical protein binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0008144	drug binding
0.35	GO:0035091	phosphatidylinositol binding

0.40	GO:0005739	mitochondrion
0.34	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.33	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.85

GO:0008193

tr|Q9V3N9|Q9V3N9_DROME
B6
Search

PTX3

0.65	Pentaxin family

0.54

GO:0046872

metal ion binding

0.66

GO:0005576

extracellular region

sp|Q9V3P0|PRDX1_DROME
Peroxiredoxin 1
Search

0.39	Thioredoxin-dependent peroxidase

0.69	GO:0098869	cellular oxidant detoxification
0.69	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0008354	germ cell migration
0.46	GO:0008340	determination of adult lifespan
0.45	GO:0072593	reactive oxygen species metabolic process
0.45	GO:0007281	germ cell development
0.44	GO:0042594	response to starvation
0.44	GO:0006979	response to oxidative stress
0.43	GO:0051187	cofactor catabolic process

0.74	GO:0051920	peroxiredoxin activity
0.53	GO:0004601	peroxidase activity
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0016972	thiol oxidase activity

0.42	GO:0005829	cytosol
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005739	mitochondrion
0.33	GO:1905369	endopeptidase complex
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.74	EC:1.11.1.15	GO:0051920
0.53	KEGG:R03532	GO:0004601

tr|Q9V3P2|Q9V3P2_DROME
LD41558p
Search

NOL10

0.76	LOW QUALITY PROTEIN: nucleolar protein 10

0.34	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.34	GO:0006402	mRNA catabolic process

0.35	GO:0004535	poly(A)-specific ribonuclease activity
0.34	GO:0003723	RNA binding
0.33	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:3.1.13.4

GO:0004535

tr|Q9V3P3|Q9V3P3_DROME
LD45860p
Search

0.73	Proteasome activator complex subunit

0.47	GO:0010950	positive regulation of endopeptidase activity
0.47	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.46	GO:0061136	regulation of proteasomal protein catabolic process
0.43	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0000398	mRNA splicing, via spliceosome

0.49	GO:0061133	endopeptidase activator activity
0.44	GO:0004866	endopeptidase inhibitor activity

0.85	GO:0008537	proteasome activator complex
0.47	GO:0005703	polytene chromosome puff
0.47	GO:0005705	polytene chromosome interband
0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V3P4|Q9V3P4_DROME
CG7953 protein
Search

0.87	Putative juvenile hormone binding protein in insects

0.72

GO:0008289

lipid binding

sp|Q9V3P6|PSMD1_DROME
26S proteasome non-ATPase regulatory subunit 1
Search

0.63	26S proteasome non-ATPase regulatory subunit

0.76	GO:0042176	regulation of protein catabolic process
0.69	GO:0050790	regulation of catalytic activity
0.38	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.37	GO:0008063	Toll signaling pathway
0.36	GO:0007623	circadian rhythm
0.33	GO:0006757	ATP generation from ADP
0.33	GO:0006090	pyruvate metabolic process
0.33	GO:0016052	carbohydrate catabolic process
0.33	GO:0019362	pyridine nucleotide metabolic process

0.70	GO:0030234	enzyme regulator activity
0.36	GO:0004175	endopeptidase activity
0.34	GO:0004082	bisphosphoglycerate mutase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0004619	phosphoglycerate mutase activity

0.72	GO:1905369	endopeptidase complex
0.59	GO:0043234	protein complex
0.45	GO:0044424	intracellular part
0.35	GO:0043233	organelle lumen
0.35	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

EC:5.4.2.4

GO:0004082

tr|Q9V3P9|Q9V3P9_DROME
Cuticular protein 35B
Search

CUP8

0.49	Pupal cuticle protein Edg-84A

0.41	GO:0040003	chitin-based cuticle development
0.35	GO:0019646	aerobic electron transport chain
0.35	GO:0006812	cation transport
0.35	GO:0098660	inorganic ion transmembrane transport
0.33	GO:0006461	protein complex assembly
0.33	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.32	GO:0042773	ATP synthesis coupled electron transport

0.77	GO:0042302	structural constituent of cuticle
0.37	GO:0008827	cytochrome o ubiquinol oxidase activity
0.34	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0009055	electron transfer activity
0.34	GO:0016151	nickel cation binding
0.32	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.32	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.39	GO:0031012	extracellular matrix
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37

EC:1.10.3

GO:0008827

tr|Q9V3Q0|Q9V3Q0_DROME
IP06404p
Search

0.55	Dynein light chain

0.60	GO:0007017	microtubule-based process
0.55	GO:0060271	cilium assembly
0.51	GO:0006928	movement of cell or subcellular component
0.50	GO:0043623	cellular protein complex assembly
0.50	GO:0007010	cytoskeleton organization
0.45	GO:0043666	regulation of phosphoprotein phosphatase activity
0.41	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.39	GO:0007165	signal transduction
0.36	GO:0055114	oxidation-reduction process

0.60	GO:0045504	dynein heavy chain binding
0.59	GO:0043014	alpha-tubulin binding
0.49	GO:0017111	nucleoside-triphosphatase activity
0.45	GO:0019888	protein phosphatase regulator activity
0.42	GO:0008312	7S RNA binding
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.36	GO:0016491	oxidoreductase activity
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0030286	dynein complex
0.48	GO:0031514	motile cilium
0.45	GO:0000159	protein phosphatase type 2A complex
0.44	GO:0044447	axoneme part
0.43	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.41	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:3.6.1.15

GO:0017111

tr|Q9V3Q1|Q9V3Q1_DROME
CG4701
Search

0.47	ATPase family AAA domain-containing protein 1-A

0.46	GO:0048190	wing disc dorsal/ventral pattern formation
0.36	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.36	GO:0002092	positive regulation of receptor internalization
0.36	GO:0007286	spermatid development
0.36	GO:0007613	memory
0.36	GO:0007612	learning
0.34	GO:0051013	microtubule severing

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016887	ATPase activity
0.34	GO:0070273	phosphatidylinositol-4-phosphate binding
0.32	GO:0140096	catalytic activity, acting on a protein

0.39	GO:1905369	endopeptidase complex
0.37	GO:0005634	nucleus
0.36	GO:0043234	protein complex
0.35	GO:0045211	postsynaptic membrane
0.34	GO:0031903	microbody membrane
0.34	GO:0044439	peroxisomal part
0.33	GO:0030054	cell junction
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.37

GO:0016887

sp|Q9V3Q2|OR35A_DROME
Odorant receptor 35a
Search

0.52	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.60	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.55	GO:0005886	plasma membrane
0.42	GO:0030425	dendrite
0.42	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V3Q4|Q9V3Q4_DROME
GH25379p
Search

PRDX4

0.37	Thioredoxin dependent peroxide reductase

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.48	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.46	GO:0046427	positive regulation of JAK-STAT cascade
0.46	GO:0072593	reactive oxygen species metabolic process
0.45	GO:0070417	cellular response to cold
0.45	GO:0097190	apoptotic signaling pathway
0.44	GO:0042742	defense response to bacterium
0.43	GO:0051187	cofactor catabolic process

0.74	GO:0051920	peroxiredoxin activity
0.50	GO:0004601	peroxidase activity
0.39	GO:0042803	protein homodimerization activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0004791	thioredoxin-disulfide reductase activity
0.32	GO:0003677	DNA binding

0.44	GO:0005783	endoplasmic reticulum
0.43	GO:0005829	cytosol
0.43	GO:0005615	extracellular space
0.36	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.74	EC:1.11.1.15	GO:0051920
0.50	KEGG:R03532	GO:0004601

sp|Q9V3Q6|M3K7_DROME
Mitogen-activated protein kinase kinase kinase 7
Search

0.52	Mitogen-activated protein kinase kinase kinase 7

0.83	GO:0000186	activation of MAPKK activity
0.79	GO:0000165	MAPK cascade
0.62	GO:0043507	positive regulation of JUN kinase activity
0.61	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.57	GO:0002702	positive regulation of production of molecular mediator of immune response
0.56	GO:0031098	stress-activated protein kinase signaling cascade
0.55	GO:0048802	notum morphogenesis
0.54	GO:0002813	regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.54	GO:0061057	peptidoglycan recognition protein signaling pathway
0.54	GO:0050778	positive regulation of immune response

0.84	GO:0004709	MAP kinase kinase kinase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0097110	scaffold protein binding
0.43	GO:0042802	identical protein binding
0.35	GO:0004708	MAP kinase kinase activity

0.48	GO:0008385	IkappaB kinase complex
0.46	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.40	GO:0005886	plasma membrane
0.35	GO:0014069	postsynaptic density
0.33	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.7.11 EC:2.7.11.25

GO:0004709

tr|Q9V3Q7|Q9V3Q7_DROME
Na/K-ATPase beta subunit isoform 4
Search

0.57	sodium/potassium-transporting ATPase subunit beta-2

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport

0.85

GO:0005890

sodium:potassium-exchanging ATPase complex

tr|Q9V3Q9|Q9V3Q9_DROME
IP03705p
Search

0.85	Gamma-aminobutyric acid type B receptor subunit

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0032223	negative regulation of synaptic transmission, cholinergic
0.33	GO:0042493	response to drug

0.85	GO:0004965	G-protein coupled GABA receptor activity
0.46	GO:0046982	protein heterodimerization activity

0.52

GO:0038039

G-protein coupled receptor heterodimeric complex

tr|Q9V3R0|Q9V3R0_DROME
Metalloendopeptidase
Search

0.61	Metalloendopeptidase

0.60	GO:0006508	proteolysis
0.39	GO:0018996	molting cycle, collagen and cuticulin-based cuticle

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0005509	calcium ion binding

0.30

GO:0031224

intrinsic component of membrane

0.70

GO:0004222

sp|Q9V3R1|A36DE_DROME
Accessory gland protein Acp36DE
Search

0.10	Accessory gland protein Acp36DE

0.87	GO:0046693	sperm storage
0.30	GO:0048583	regulation of response to stimulus
0.30	GO:0065008	regulation of biological quality
0.30	GO:0045297	post-mating behavior
0.30	GO:0060180	female mating behavior
0.30	GO:0065009	regulation of molecular function
0.30	GO:0050794	regulation of cellular process
0.30	GO:0023051	regulation of signaling

0.30	GO:0005102	receptor binding
0.30	GO:0098772	molecular function regulator

0.73

GO:0005615

extracellular space

tr|Q9V3R3|Q9V3R3_DROME
CG3704
Search

0.77	GPN-loop GTPase

0.49	GO:0034504	protein localization to nucleus
0.47	GO:0007064	mitotic sister chromatid cohesion
0.45	GO:0017038	protein import
0.44	GO:0051170	nuclear import
0.44	GO:0072594	establishment of protein localization to organelle
0.43	GO:0044376	RNA polymerase II complex import to nucleus
0.42	GO:0034629	cellular protein complex localization
0.36	GO:1901800	positive regulation of proteasomal protein catabolic process
0.34	GO:0030163	protein catabolic process
0.33	GO:0051301	cell division

0.67	GO:0003924	GTPase activity
0.41	GO:0016887	ATPase activity
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding
0.32	GO:0005515	protein binding

0.46	GO:0005665	DNA-directed RNA polymerase II, core complex
0.33	GO:0005874	microtubule
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.41

GO:0016887

sp|Q9V3R6|ADAT1_DROME
tRNA-specific adenosine deaminase 1
Search

0.24	tRNA-specific adenosine deaminase

0.63	GO:0006396	RNA processing
0.47	GO:0009451	RNA modification
0.45	GO:0006399	tRNA metabolic process
0.42	GO:0007268	chemical synaptic transmission
0.40	GO:0021566	hypoglossal nerve development
0.40	GO:0009887	animal organ morphogenesis
0.40	GO:0097049	motor neuron apoptotic process
0.40	GO:0021965	spinal cord ventral commissure morphogenesis
0.40	GO:0061744	motor behavior
0.40	GO:0009888	tissue development

0.79	GO:0004000	adenosine deaminase activity
0.59	GO:0003723	RNA binding
0.41	GO:0019992	diacylglycerol binding
0.39	GO:0005543	phospholipid binding
0.39	GO:0008528	G-protein coupled peptide receptor activity
0.38	GO:0005509	calcium ion binding
0.33	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.33	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.32	GO:0016491	oxidoreductase activity

0.37	GO:0005730	nucleolus
0.36	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:3.5.4.4

GO:0004000

sp|Q9V3R8|UBIA1_DROME
UbiA prenyltransferase domain-containing protein 1 homolog
Search

0.43	UbiA prenyltransferase domain-containing protein 1

0.50	GO:0035207	negative regulation of hemocyte proliferation
0.50	GO:0045614	negative regulation of plasmatocyte differentiation
0.50	GO:0035203	regulation of lamellocyte differentiation
0.49	GO:0008592	regulation of Toll signaling pathway
0.49	GO:0035167	larval lymph gland hemopoiesis
0.48	GO:0009234	menaquinone biosynthetic process
0.48	GO:0070584	mitochondrion morphogenesis
0.48	GO:0042371	vitamin K biosynthetic process
0.48	GO:0048581	negative regulation of post-embryonic development
0.47	GO:1903707	negative regulation of hemopoiesis

0.70	GO:0004659	prenyltransferase activity
0.40	GO:0016209	antioxidant activity
0.36	GO:0004517	nitric-oxide synthase activity

0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0030173	integral component of Golgi membrane
0.40	GO:0005739	mitochondrion
0.37	GO:0005634	nucleus
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031967	organelle envelope

0.70

EC:2.5.1

GO:0004659

sp|Q9V3S0|CP4G1_DROME
Cytochrome P450 4g1
Search

0.38	Cytochrome P450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0006723	cuticle hydrocarbon biosynthetic process
0.35	GO:0048036	central complex development
0.35	GO:0007629	flight behavior
0.35	GO:0007614	short-term memory
0.35	GO:0016319	mushroom body development
0.33	GO:0006886	intracellular protein transport
0.32	GO:0055085	transmembrane transport

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.50	GO:0071771	aldehyde decarbonylase activity
0.34	GO:0008536	Ran GTPase binding

0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|Q9V3S3|Q9V3S3_DROME
Protamine A, isoform A
Search

0.90

Protamine

0.86	GO:0035092	sperm chromatin condensation
0.66	GO:0043486	histone exchange

0.59	GO:0000785	chromatin
0.42	GO:0044454	nuclear chromosome part

tr|Q9V3S6|Q9V3S6_DROME
BARBU
Search

0.96	Enhancer of split malpha protein (Fragment)

0.82	GO:0007219	Notch signaling pathway
0.79	GO:0007423	sensory organ development
0.69	GO:0060582	cell fate determination involved in pattern specification
0.68	GO:0010160	formation of animal organ boundary
0.66	GO:0045746	negative regulation of Notch signaling pathway
0.65	GO:0001736	establishment of planar polarity
0.65	GO:0001708	cell fate specification

0.40

GO:0031625

ubiquitin protein ligase binding

0.42

GO:0005737

cytoplasm

tr|Q9V3S7|Q9V3S7_DROME
BcDNA.GH12326
Search

0.38	GO:0016311	dephosphorylation
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression
0.33	GO:0009967	positive regulation of signal transduction
0.32	GO:0007165	signal transduction

0.38	GO:0016791	phosphatase activity
0.33	GO:0035591	signaling adaptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016791

sp|Q9V3S9|BGM_DROME
Very long-chain-fatty-acid--CoA ligase bubblegum
Search

0.43	Very long-chain-fatty-acid--CoA ligase bubblegum

0.55	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.54	GO:0070050	neuron cellular homeostasis
0.52	GO:0001676	long-chain fatty acid metabolic process
0.48	GO:0034976	response to endoplasmic reticulum stress
0.42	GO:0070328	triglyceride homeostasis
0.42	GO:0007498	mesoderm development
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.53	GO:0016874	ligase activity
0.35	GO:0047617	acyl-CoA hydrolase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding

0.34	GO:0005829	cytosol
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.53

GO:0016874

tr|Q9V3T1|Q9V3T1_DROME
EG:BACR7A4.16 protein
Search

MUS81

0.61	crossover junction endonuclease MUS81

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.47	GO:0006281	DNA repair
0.46	GO:0000712	resolution of meiotic recombination intermediates
0.45	GO:0031573	intra-S DNA damage checkpoint
0.43	GO:0031297	replication fork processing
0.42	GO:0044818	mitotic G2/M transition checkpoint
0.40	GO:0031572	G2 DNA damage checkpoint
0.38	GO:0010520	regulation of reciprocal meiotic recombination
0.38	GO:0000076	DNA replication checkpoint
0.36	GO:0006308	DNA catabolic process

0.64	GO:0004518	nuclease activity
0.55	GO:0003677	DNA binding
0.39	GO:0140097	catalytic activity, acting on DNA
0.33	GO:0046872	metal ion binding
0.33	GO:0004857	enzyme inhibitor activity

0.43	GO:0048476	Holliday junction resolvase complex
0.38	GO:0005634	nucleus

0.64

GO:0004518

tr|Q9V3T2|Q9V3T2_DROME
CG5254, isoform A
Search

SLC25A21

0.59	Mitochondrial oxodicarboxylate carrier

0.43	GO:0006839	mitochondrial transport
0.43	GO:0006835	dicarboxylic acid transport
0.42	GO:0055085	transmembrane transport
0.34	GO:0006554	lysine catabolic process
0.33	GO:0051181	cofactor transport
0.33	GO:0006468	protein phosphorylation

0.44	GO:0005310	dicarboxylic acid transmembrane transporter activity
0.34	GO:0051184	cofactor transmembrane transporter activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V3T7|Q9V3T7_DROME
Uncharacterized protein
Search

tr|Q9V3T8|Q9V3T8_DROME
LD32469p
Search

0.39	Serine and arginine rich splicing factor 2

0.63	GO:0043484	regulation of RNA splicing
0.48	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.47	GO:0031440	regulation of mRNA 3'-end processing
0.34	GO:0050482	arachidonic acid secretion
0.33	GO:0006644	phospholipid metabolic process

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0004623	phospholipase A2 activity

0.45	GO:0016607	nuclear speck
0.43	GO:0000785	chromatin
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

EC:3.1.1.4

GO:0004623

sp|Q9V3T9|ADRO_DROME
NADPH:adrenodoxin oxidoreductase, mitochondrial
Search

0.77	NADPH:adrenodoxin oxidoreductase, mitochondrial

0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035073	pupariation
0.49	GO:0007591	molting cycle, chitin-based cuticle
0.49	GO:0042048	olfactory behavior
0.48	GO:0007552	metamorphosis
0.47	GO:0008202	steroid metabolic process
0.42	GO:0008610	lipid biosynthetic process
0.42	GO:0006744	ubiquinone biosynthetic process
0.38	GO:1901362	organic cyclic compound biosynthetic process
0.38	GO:1902652	secondary alcohol metabolic process

0.82	GO:0015039	NADPH-adrenodoxin reductase activity
0.37	GO:0003713	transcription coactivator activity
0.35	GO:0008168	methyltransferase activity
0.35	GO:0004324	ferredoxin-NADP+ reductase activity
0.35	GO:0050661	NADP binding
0.35	GO:0005515	protein binding
0.34	GO:0009055	electron transfer activity
0.33	GO:0043168	anion binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding

0.71	GO:0005759	mitochondrial matrix
0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.33	GO:0015935	small ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:1.18.1.6

GO:0015039

sp|Q9V3U0|BGML_DROME
Long-chain-fatty-acid--CoA ligase bubblegum-like
Search

0.47	Very long-chain-fatty-acid--CoA ligase bubblegum

0.60	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.59	GO:0070050	neuron cellular homeostasis
0.55	GO:0001676	long-chain fatty acid metabolic process
0.53	GO:0070328	triglyceride homeostasis
0.52	GO:0007498	mesoderm development
0.44	GO:0034976	response to endoplasmic reticulum stress

0.55	GO:0004467	long-chain fatty acid-CoA ligase activity
0.39	GO:0102391	decanoate--CoA ligase activity
0.36	GO:0047617	acyl-CoA hydrolase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046983	protein dimerization activity

0.34	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.55

EC:6.2.1.3

GO:0004467

sp|Q9V3U2|NHP2_DROME
H/ACA ribonucleoprotein complex subunit 2-like protein
Search

0.55	H/ACA ribonucleoprotein complex subunit

0.52	GO:0042254	ribosome biogenesis
0.43	GO:0031120	snRNA pseudouridine synthesis
0.41	GO:0043043	peptide biosynthetic process
0.40	GO:0034470	ncRNA processing
0.40	GO:0090501	RNA phosphodiester bond hydrolysis
0.40	GO:0016072	rRNA metabolic process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0009059	macromolecule biosynthetic process
0.36	GO:0006399	tRNA metabolic process

0.49	GO:0003723	RNA binding
0.41	GO:0003735	structural constituent of ribosome
0.37	GO:0004526	ribonuclease P activity

0.60	GO:0019013	viral nucleocapsid
0.59	GO:0030529	intracellular ribonucleoprotein complex
0.58	GO:0005730	nucleolus
0.40	GO:0044444	cytoplasmic part
0.37	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.1.26.5

GO:0004526

tr|Q9V3U5|Q9V3U5_DROME
CG7916
Search

0.59	Hemolymph juvenile hormone binding protein (JHBP)

0.72

GO:0008289

lipid binding

tr|Q9V3U6|Q9V3U6_DROME
26-29kD-proteinase
Search

0.56	Counting factor associated protein D

0.61	GO:0006508	proteolysis
0.35	GO:0044257	cellular protein catabolic process
0.34	GO:0007017	microtubule-based process
0.34	GO:0007010	cytoskeleton organization

0.72	GO:0008234	cysteine-type peptidase activity
0.34	GO:0008289	lipid binding
0.34	GO:0004175	endopeptidase activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005764	lysosome
0.35	GO:0005615	extracellular space
0.34	GO:0005874	microtubule
0.30	GO:0016020	membrane

0.72

GO:0008234

tr|Q9V3U7|Q9V3U7_DROME
GEO12036p1
Search

sp|Q9V3U9|SLMO_DROME
Protein slowmo
Search

0.58	Member of the intramitochondrial sorting protein family

0.50	GO:0030432	peristalsis
0.50	GO:0030706	germarium-derived oocyte differentiation
0.50	GO:0008345	larval locomotory behavior
0.46	GO:0007283	spermatogenesis
0.39	GO:0015914	phospholipid transport
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0007275	multicellular organism development
0.32	GO:0006260	DNA replication

0.41	GO:1990050	phosphatidic acid transporter activity
0.32	GO:0016787	hydrolase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0005758	mitochondrial intermembrane space
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q9V3V0|Q9V3V0_DROME
DXl6 protein
Search

0.83	Serine/arginine-rich splicing factor

0.53	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.52	GO:0031440	regulation of mRNA 3'-end processing
0.51	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.47	GO:0008380	RNA splicing
0.38	GO:0006397	mRNA processing
0.34	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.33	GO:0032392	DNA geometric change
0.33	GO:0006260	DNA replication
0.32	GO:0016310	phosphorylation

0.61	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.34	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.33	GO:0003678	DNA helicase activity
0.32	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.36	GO:1902494	catalytic complex
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.33	GO:0019898	extrinsic component of membrane
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016021	integral component of membrane

tr|Q9V3V1|Q9V3V1_DROME
EG:BACR42I17.12 protein
Search

0.47	GO:0016055	Wnt signaling pathway
0.45	GO:0007275	multicellular organism development

0.59	GO:0003723	RNA binding
0.45	GO:0099600	transmembrane receptor activity
0.43	GO:0038023	signaling receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|Q9V3V3|Q9V3V3_DROME
Pez, isoform A
Search

0.95	Protein tyrosine phosphatase PTPpez

0.69	GO:0035335	peptidyl-tyrosine dephosphorylation
0.68	GO:0035331	negative regulation of hippo signaling
0.67	GO:2000647	negative regulation of stem cell proliferation
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.70	GO:0004725	protein tyrosine phosphatase activity
0.41	GO:0008092	cytoskeletal protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0003735	structural constituent of ribosome

0.68	GO:0005856	cytoskeleton
0.62	GO:0045177	apical part of cell
0.59	GO:0005938	cell cortex
0.33	GO:0015934	large ribosomal subunit

0.70

EC:3.1.3.48

GO:0004725

tr|Q9V3V6|Q9V3V6_DROME
26S proteasome regulatory complex subunit p50
Search

0.64	Tat-binding protein-1

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.53	GO:0006508	proteolysis
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.40	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.39	GO:0034976	response to endoplasmic reticulum stress
0.39	GO:0010243	response to organonitrogen compound
0.39	GO:0052472	modulation by host of symbiont transcription

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008233	peptidase activity
0.39	GO:0017025	TBP-class protein binding
0.37	GO:0042802	identical protein binding
0.34	GO:0008568	microtubule-severing ATPase activity

0.50	GO:1905369	endopeptidase complex
0.48	GO:0005737	cytoplasm
0.44	GO:0043234	protein complex
0.37	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.36	GO:0035770	ribonucleoprotein granule
0.35	GO:0044446	intracellular organelle part

0.51

GO:0008233

sp|Q9V3V7|SPC25_DROME
Kinetochore protein Spc25
Search

SPC25

0.78	Kinetochore protein Spc25

0.86	GO:0051311	meiotic metaphase plate congression
0.85	GO:0000212	meiotic spindle organization
0.85	GO:0007080	mitotic metaphase plate congression
0.67	GO:0051301	cell division

0.41

GO:0005515

protein binding

0.86	GO:0031262	Ndc80 complex
0.80	GO:0000777	condensed chromosome kinetochore
0.61	GO:0005634	nucleus

tr|Q9V3V9|Q9V3V9_DROME
Endonuclease G inhibitor, isoform A
Search

0.65	GO:0008045	motor neuron axon guidance
0.64	GO:0045747	positive regulation of Notch signaling pathway
0.64	GO:0060702	negative regulation of endoribonuclease activity
0.30	GO:0006950	response to stress
0.30	GO:0044237	cellular metabolic process
0.30	GO:0051276	chromosome organization
0.30	GO:1901360	organic cyclic compound metabolic process
0.30	GO:0044238	primary metabolic process
0.30	GO:0042592	homeostatic process
0.30	GO:0006807	nitrogen compound metabolic process

0.62	GO:0008428	ribonuclease inhibitor activity
0.58	GO:0016817	hydrolase activity, acting on acid anhydrides
0.30	GO:1901363	heterocyclic compound binding
0.30	GO:0016788	hydrolase activity, acting on ester bonds
0.30	GO:0097159	organic cyclic compound binding

0.49	GO:0005634	nucleus
0.30	GO:0032991	macromolecular complex
0.30	GO:0000781	chromosome, telomeric region
0.30	GO:0043233	organelle lumen

0.58

EC:3.6

GO:0016817

sp|Q9V3W0|UK114_DROME
RutC family protein UK114
Search

0.39	Reactive intermediate/imine deaminase

0.62

GO:0006457

protein folding

0.41

GO:0016787

hydrolase activity

0.30

GO:0044425

membrane part

0.41

GO:0016787

tr|Q9V3W1|Q9V3W1_DROME
Tetratricopeptide repeat protein 2
Search

0.66	Tetratricopeptide repeat protein 2

0.71	GO:0051085	chaperone cofactor-dependent protein refolding
0.40	GO:0016310	phosphorylation

0.67	GO:0031072	heat shock protein binding
0.50	GO:0051082	unfolded protein binding
0.41	GO:0016301	kinase activity
0.41	GO:0005509	calcium ion binding

0.59	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol
0.44	GO:0070062	extracellular exosome
0.37	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

tr|Q9V3W2|Q9V3W2_DROME
GM23292p
Search

0.44	Phosphatidylethanolamine-binding protein 1

0.38	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.36	GO:0006401	RNA catabolic process

0.37	GO:0003724	RNA helicase activity
0.37	GO:0003954	NADH dehydrogenase activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0003723	RNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0003724

sp|Q9V3W6|INX7_DROME
Innexin inx7
Search

INX

0.64

Innexin

0.59	GO:0006811	ion transport
0.51	GO:0072375	medium-term memory
0.45	GO:0010496	intercellular transport
0.41	GO:0016331	morphogenesis of embryonic epithelium
0.40	GO:0036098	male germ-line stem cell population maintenance
0.40	GO:0030727	germarium-derived female germ-line cyst formation
0.40	GO:0007440	foregut morphogenesis
0.38	GO:0007283	spermatogenesis
0.38	GO:0001700	embryonic development via the syncytial blastoderm
0.36	GO:0055085	transmembrane transport

0.43

GO:0005243

gap junction channel activity

0.81	GO:0005921	gap junction
0.56	GO:0005886	plasma membrane
0.40	GO:0005634	nucleus
0.39	GO:0045177	apical part of cell
0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|Q9V3W7|Q9V3W7_DROME
LD40489p
Search

0.81	Arginine/serine-rich splicing factor

0.48	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.48	GO:0031440	regulation of mRNA 3'-end processing
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0006069	ethanol oxidation
0.35	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0042254	ribosome biogenesis
0.34	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.33	GO:0019079	viral genome replication

0.59	GO:0003723	RNA binding
0.38	GO:0003677	DNA binding
0.36	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.35	GO:0044446	intracellular organelle part
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005770	late endosome
0.34	GO:0045121	membrane raft
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:1902494	catalytic complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0098588	bounding membrane of organelle
0.32	GO:0098796	membrane protein complex

0.36	EC:1.1.1.284	GO:0051903
0.36	KEGG:R06983 KEGG:R07140	GO:0051903

tr|Q9V3W9|Q9V3W9_DROME
DNA repair protein Rad23
Search

0.64	UV excision repair protein RAD23 like protein B

0.77	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.73	GO:0006289	nucleotide-excision repair
0.51	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.44	GO:0051276	chromosome organization
0.44	GO:0007283	spermatogenesis
0.36	GO:0048568	embryonic organ development
0.33	GO:0065004	protein-DNA complex assembly
0.33	GO:0016579	protein deubiquitination
0.33	GO:0006457	protein folding
0.32	GO:0043043	peptide biosynthetic process

0.73	GO:0003684	damaged DNA binding
0.52	GO:0031593	polyubiquitin modification-dependent protein binding
0.33	GO:0003697	single-stranded DNA binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.43	GO:1990391	DNA repair complex
0.41	GO:0005829	cytosol
0.41	GO:0043233	organelle lumen
0.39	GO:0043234	protein complex
0.38	GO:0044446	intracellular organelle part
0.36	GO:1905369	endopeptidase complex
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V3X3|Q9V3X3_DROME
EG:BACR43E12.1 protein
Search

0.13	RNA polymerase-associated protein Rtf1

0.81	GO:0006368	transcription elongation from RNA polymerase II promoter
0.74	GO:0016570	histone modification
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0006414	translational elongation

0.55	GO:0003677	DNA binding
0.53	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding
0.48	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.37	GO:0003746	translation elongation factor activity
0.33	GO:0046872	metal ion binding

0.81

GO:0016593

Cdc73/Paf1 complex

sp|Q9V3X4|BSCL2_DROME
Seipin
Search

0.93	Adipose regulatory protein (Fragment)

0.84	GO:0019915	lipid storage
0.55	GO:0048687	positive regulation of sprouting of injured axon
0.55	GO:0048690	regulation of axon extension involved in regeneration
0.54	GO:0046339	diacylglycerol metabolic process
0.53	GO:0010884	positive regulation of lipid storage
0.53	GO:0045773	positive regulation of axon extension
0.53	GO:0090207	regulation of triglyceride metabolic process
0.53	GO:0032469	endoplasmic reticulum calcium ion homeostasis
0.51	GO:0046473	phosphatidic acid metabolic process
0.50	GO:0046890	regulation of lipid biosynthetic process

0.33	GO:0016491	oxidoreductase activity
0.33	GO:0003735	structural constituent of ribosome

0.46	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.34	GO:0015934	large ribosomal subunit
0.30	GO:0016021	integral component of membrane

0.33

GO:0016491

sp|Q9V3X5|TMTC2_DROME
Transmembrane and TPR repeat-containing protein CG4341
Search

0.87	Transmembrane and TPR repeat-containing protein CG4341

0.42	GO:0006396	RNA processing
0.34	GO:0006493	protein O-linked glycosylation
0.34	GO:0097502	mannosylation

0.36	GO:0042802	identical protein binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003676	nucleic acid binding
0.34	GO:0000030	mannosyltransferase activity
0.33	GO:0008270	zinc ion binding

0.30

GO:0031224

intrinsic component of membrane

0.34

GO:0000030

tr|Q9V3X8|Q9V3X8_DROME
EG:BACR42I17.11 protein
Search

0.11	gastrula zinc finger protein XlCGF8.2DB

0.67	GO:0048813	dendrite morphogenesis
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0006508	proteolysis
0.34	GO:0006281	DNA repair

0.51	GO:0003676	nucleic acid binding
0.50	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0008270	zinc ion binding
0.34	GO:0004252	serine-type endopeptidase activity

0.48

GO:0005634

nucleus

0.34

GO:0004252

tr|Q9V3Y0|Q9V3Y0_DROME
Lethal (2) 35Be
Search

ANKRD49

0.46	ankyrin repeat domain-containing protein 49

0.64	GO:0045893	positive regulation of transcription, DNA-templated
0.54	GO:0016559	peroxisome fission
0.42	GO:0007283	spermatogenesis
0.40	GO:0030154	cell differentiation
0.38	GO:0015031	protein transport

0.39	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.35	GO:0005515	protein binding

0.53	GO:0005779	integral component of peroxisomal membrane
0.43	GO:0005829	cytosol
0.39	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005634	nucleus

0.39

EC:2.3.1.225

GO:0019706

sp|Q9V3Y2|DRE2_DROME
Anamorsin homolog
Search

0.83

Anamorsin

0.77	GO:0006915	apoptotic process
0.74	GO:0031163	metallo-sulfur cluster assembly
0.73	GO:0043066	negative regulation of apoptotic process
0.65	GO:0006790	sulfur compound metabolic process
0.63	GO:0051188	cofactor biosynthetic process
0.57	GO:0022900	electron transport chain
0.52	GO:0048856	anatomical structure development
0.51	GO:0032501	multicellular organismal process
0.48	GO:0019953	sexual reproduction
0.48	GO:0003006	developmental process involved in reproduction

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.58	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding
0.43	GO:0008168	methyltransferase activity
0.32	GO:0005515	protein binding

0.79	GO:0005758	mitochondrial intermembrane space
0.43	GO:0005634	nucleus
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0008168

sp|Q9V3Y3|DFP_DROME
Defense protein l(2)34Fc
Search

0.91	Defense protein l(2)34Fc

0.86	GO:0042832	defense response to protozoan
0.72	GO:0050777	negative regulation of immune response
0.44	GO:0045087	innate immune response
0.44	GO:0042742	defense response to bacterium
0.34	GO:0055114	oxidation-reduction process

0.41	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|Q9V3Y4|Q9V3Y4_DROME
LD43650p
Search

0.48	Mitochondrial carrier like protein 2

0.41	GO:0070585	protein localization to mitochondrion
0.40	GO:0043065	positive regulation of apoptotic process
0.36	GO:0045444	fat cell differentiation
0.36	GO:0001889	liver development
0.36	GO:0048565	digestive tract development
0.33	GO:0015711	organic anion transport
0.32	GO:0055085	transmembrane transport

0.33	GO:0008514	organic anion transmembrane transporter activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005739	mitochondrion
0.34	GO:0070062	extracellular exosome
0.33	GO:0019866	organelle inner membrane
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus

tr|Q9V3Y5|Q9V3Y5_DROME
BcDNA.LD23634
Search

0.11	RNA-binding protein 25

0.69	GO:0006397	mRNA processing
0.46	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.38	GO:0042981	regulation of apoptotic process
0.38	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.33	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006457	protein folding
0.32	GO:0055114	oxidation-reduction process

0.54	GO:0003723	RNA binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0004497	monooxygenase activity

0.42	GO:0005681	spliceosomal complex
0.40	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0003755

tr|Q9V3Y7|Q9V3Y7_DROME
Uncharacterized protein, isoform A
Search

0.66

GO:0005576

extracellular region

tr|Q9V3Y8|Q9V3Y8_DROME
FI05319p
Search

0.59	Inhibitor of nuclear factor kappa-B kinase subunit epsilon

0.63	GO:0006468	protein phosphorylation
0.55	GO:0045035	sensory organ precursor cell division
0.55	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.54	GO:0008407	chaeta morphogenesis
0.53	GO:0016322	neuron remodeling
0.53	GO:0007314	oocyte anterior/posterior axis specification
0.52	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.52	GO:0032456	endocytic recycling
0.52	GO:0018209	peptidyl-serine modification
0.51	GO:0001578	microtubule bundle formation

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0017137	Rab GTPase binding
0.34	GO:0004871	signal transducer activity

0.51	GO:0051286	cell tip
0.38	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|Q9V3Z1|Q9V3Z1_DROME
RH69304p
Search

0.64

Tribbles

0.65	GO:0007370	ventral furrow formation
0.64	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.63	GO:0006468	protein phosphorylation
0.63	GO:0046627	negative regulation of insulin receptor signaling pathway
0.59	GO:0045839	negative regulation of mitotic nuclear division
0.45	GO:1903507	negative regulation of nucleic acid-templated transcription
0.44	GO:0035556	intracellular signal transduction
0.41	GO:0033129	positive regulation of histone phosphorylation
0.41	GO:0070498	interleukin-1-mediated signaling pathway
0.41	GO:0035066	positive regulation of histone acetylation

0.64	GO:0004672	protein kinase activity
0.56	GO:0042803	protein homodimerization activity
0.55	GO:0046982	protein heterodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0003714	transcription corepressor activity
0.44	GO:0000287	magnesium ion binding
0.41	GO:0031434	mitogen-activated protein kinase kinase binding
0.33	GO:0010181	FMN binding

0.49	GO:0005634	nucleus
0.38	GO:0005938	cell cortex
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.32	GO:0005829	cytosol
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.33

EC:1.6.5.3

GO:0008137

sp|Q9V3Z2|SER7_DROME
Serine protease 7
Search

0.37	Prophenoloxidase activating protease I

0.61	GO:0006508	proteolysis
0.58	GO:0035008	positive regulation of melanization defense response
0.57	GO:0035006	melanization defense response
0.41	GO:0009620	response to fungus
0.37	GO:0042381	hemolymph coagulation

0.69	GO:0004252	serine-type endopeptidase activity
0.32	GO:0003677	DNA binding

0.36	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|Q9V3Z3|Q9V3Z3_DROME
LD26007p
Search

0.66	Caspase recruitment domain-containing protein 11

0.84

GO:0007498

mesoderm development

tr|Q9V3Z4|Q9V3Z4_DROME
GH11341p
Search

PSD12

0.56	26S proteasome non-ATPase regulatory subunit 12

0.43	GO:0008063	Toll signaling pathway
0.43	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.42	GO:0007623	circadian rhythm

0.73	GO:1905369	endopeptidase complex
0.60	GO:0043234	protein complex
0.45	GO:0044424	intracellular part
0.40	GO:0043233	organelle lumen
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q9V3Z6|MYO7A_DROME
Myosin-VIIa
Search

0.75	Myosin class v heavy chain

0.74	GO:0007018	microtubule-based movement
0.46	GO:0048800	antennal morphogenesis
0.45	GO:0008407	chaeta morphogenesis
0.45	GO:0035317	imaginal disc-derived wing hair organization
0.45	GO:0032529	follicle cell microvillus organization
0.44	GO:0030048	actin filament-based movement
0.44	GO:0035293	chitin-based larval cuticle pattern formation
0.43	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.43	GO:0007605	sensory perception of sound
0.40	GO:0007015	actin filament organization

0.76	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0032027	myosin light chain binding
0.45	GO:0030898	actin-dependent ATPase activity
0.42	GO:0045296	cadherin binding

0.77	GO:0016459	myosin complex
0.46	GO:0070825	micropyle
0.46	GO:0035182	female germline ring canal outer rim
0.44	GO:0045180	basal cortex
0.43	GO:0045179	apical cortex
0.43	GO:0031941	filamentous actin
0.43	GO:0005902	microvillus
0.30	GO:0016020	membrane

tr|Q9V3Z7|Q9V3Z7_DROME
CG4161, isoform A
Search

0.43	protein-glutamate O-methyltransferase

0.55	GO:0032259	methylation
0.54	GO:0008213	protein alkylation
0.49	GO:0016311	dephosphorylation
0.45	GO:2001020	regulation of response to DNA damage stimulus
0.34	GO:0007165	signal transduction

0.53	GO:0051998	protein carboxyl O-methyltransferase activity
0.49	GO:0016791	phosphatase activity
0.43	GO:0019899	enzyme binding
0.38	GO:0003723	RNA binding
0.36	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.34	GO:0071949	FAD binding

0.35

GO:0005576

extracellular region

0.49

GO:0016791

tr|Q9V3Z8|Q9V3Z8_DROME
AT18988p
Search

0.10	E3 ubiquitin-protein ligase RFWD3

0.83	GO:0036297	interstrand cross-link repair
0.72	GO:0016567	protein ubiquitination
0.53	GO:2000001	regulation of DNA damage checkpoint
0.53	GO:0031571	mitotic G1 DNA damage checkpoint
0.52	GO:0031297	replication fork processing
0.51	GO:0010212	response to ionizing radiation
0.49	GO:0000724	double-strand break repair via homologous recombination
0.37	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0006468	protein phosphorylation
0.34	GO:0032008	positive regulation of TOR signaling

0.73	GO:0004842	ubiquitin-protein transferase activity
0.55	GO:0097371	MDM2/MDM4 family protein binding
0.52	GO:0002039	p53 binding
0.48	GO:0016874	ligase activity
0.38	GO:0008270	zinc ion binding
0.36	GO:0004672	protein kinase activity
0.36	GO:0004871	signal transducer activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.51	GO:0090734	site of DNA damage
0.45	GO:0031974	membrane-enclosed lumen
0.34	GO:0061700	GATOR2 complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.48	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

tr|Q9V3Z9|Q9V3Z9_DROME
HL02234p
Search

0.54	Neurofilament heavy polypeptide (Fragment)

0.76

GO:0035220

wing disc development

0.30

GO:0044425

membrane part

tr|Q9V400|Q9V400_DROME
Integrin linked kinase, isoform A
Search

ILK

0.49	integrin-linked protein kinase

0.64	GO:0007229	integrin-mediated signaling pathway
0.63	GO:0006468	protein phosphorylation
0.47	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.47	GO:0016203	muscle attachment
0.46	GO:0007160	cell-matrix adhesion
0.39	GO:0034446	substrate adhesion-dependent cell spreading
0.37	GO:0018212	peptidyl-tyrosine modification
0.37	GO:0007016	cytoskeletal anchoring at plasma membrane
0.34	GO:0035556	intracellular signal transduction
0.34	GO:0035989	tendon development

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004871	signal transducer activity
0.34	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.34	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.34	GO:0005515	protein binding
0.34	GO:0004623	phospholipase A2 activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.46	GO:0005925	focal adhesion
0.39	GO:0097517	contractile actin filament bundle
0.39	GO:0042641	actomyosin
0.34	GO:0042383	sarcolemma
0.34	GO:0030018	Z disc

0.34

EC:3.1.1.4

GO:0004623

tr|Q9V401|Q9V401_DROME
RE43371p
Search

0.41	Chromosomal replication initiator protein DnaA (Fragment)

0.44	GO:0007605	sensory perception of sound
0.44	GO:0007165	signal transduction
0.43	GO:0000413	protein peptidyl-prolyl isomerization
0.43	GO:0010466	negative regulation of peptidase activity
0.40	GO:0005975	carbohydrate metabolic process
0.37	GO:0055085	transmembrane transport

0.45	GO:0004871	signal transducer activity
0.43	GO:0030246	carbohydrate binding
0.43	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.43	GO:0030414	peptidase inhibitor activity
0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.39	GO:0008270	zinc ion binding
0.39	GO:0003723	RNA binding
0.38	GO:0022857	transmembrane transporter activity
0.36	GO:0016740	transferase activity

0.45	GO:0005576	extracellular region
0.44	GO:0019028	viral capsid
0.30	GO:0016020	membrane

0.43

GO:0003755

tr|Q9V402|Q9V402_DROME
Metalloendopeptidase
Search

0.52	Metalloendopeptidase

0.61	GO:0006508	proteolysis
0.49	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.40	GO:0032447	protein urmylation
0.39	GO:0034227	tRNA thio-modification
0.38	GO:0002098	tRNA wobble uridine modification
0.34	GO:0006629	lipid metabolic process
0.34	GO:0006030	chitin metabolic process
0.33	GO:0051604	protein maturation
0.32	GO:0090407	organophosphate biosynthetic process
0.32	GO:0006796	phosphate-containing compound metabolic process

0.70	GO:0004222	metalloendopeptidase activity
0.62	GO:0008270	zinc ion binding
0.37	GO:0000049	tRNA binding
0.36	GO:0016779	nucleotidyltransferase activity
0.34	GO:0004609	phosphatidylserine decarboxylase activity
0.34	GO:0008061	chitin binding

0.35	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm
0.33	GO:0031301	integral component of organelle membrane
0.32	GO:0019866	organelle inner membrane
0.32	GO:0043231	intracellular membrane-bounded organelle

0.70	EC:3.4.24	GO:0004222
0.34	KEGG:R02055	GO:0004609

tr|Q9V404|Q9V404_DROME
EG:BACR43E12.6 protein
Search

tr|Q9V405|Q9V405_DROME
26S proteasome regulatory complex subunit p48A
Search

0.67	26S protease regulatory subunit

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.69	GO:0030163	protein catabolic process
0.53	GO:0006508	proteolysis
0.39	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.38	GO:0034976	response to endoplasmic reticulum stress
0.37	GO:0010243	response to organonitrogen compound
0.37	GO:0043632	modification-dependent macromolecule catabolic process
0.35	GO:0008063	Toll signaling pathway
0.34	GO:0051013	microtubule severing
0.34	GO:0007623	circadian rhythm

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008233	peptidase activity
0.38	GO:0017025	TBP-class protein binding
0.34	GO:0008568	microtubule-severing ATPase activity

0.48	GO:0005737	cytoplasm
0.44	GO:1905369	endopeptidase complex
0.40	GO:0001673	male germ cell nucleus
0.40	GO:0043234	protein complex
0.36	GO:0031981	nuclear lumen
0.30	GO:0016020	membrane

0.53

GO:0008233

tr|Q9V406|Q9V406_DROME
Activator protein 4
Search

0.47	Transcription factor AP-4

0.72	GO:0007526	larval somatic muscle development
0.41	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.39	GO:0043922	negative regulation by host of viral transcription
0.39	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.39	GO:0043923	positive regulation by host of viral transcription
0.39	GO:0071549	cellular response to dexamethasone stimulus
0.39	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.39	GO:0071157	negative regulation of cell cycle arrest
0.39	GO:0043392	negative regulation of DNA binding

0.69	GO:0017022	myosin binding
0.68	GO:0046983	protein dimerization activity
0.55	GO:0043565	sequence-specific DNA binding
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0042826	histone deacetylase binding
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0042802	identical protein binding
0.37	GO:0003690	double-stranded DNA binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0035064	methylated histone binding

0.53	GO:0005634	nucleus
0.38	GO:0017053	transcriptional repressor complex
0.35	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|Q9V407|AXN_DROME
Axin
Search

AXN

0.95	Putative regulator of g protein signaling

0.77	GO:0016055	Wnt signaling pathway
0.60	GO:0035293	chitin-based larval cuticle pattern formation
0.59	GO:0007455	eye-antennal disc morphogenesis
0.59	GO:0007367	segment polarity determination
0.59	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.59	GO:0007450	dorsal/ventral pattern formation, imaginal disc
0.58	GO:0035019	somatic stem cell population maintenance
0.57	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.56	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.55	GO:0048477	oogenesis

0.62	GO:0032947	protein complex scaffold activity
0.56	GO:0008013	beta-catenin binding
0.53	GO:0019901	protein kinase binding
0.51	GO:0005102	receptor binding
0.38	GO:0005096	GTPase activator activity

0.66	GO:0030877	beta-catenin destruction complex
0.45	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.37	GO:0005829	cytosol

sp|Q9V411|NOG1_DROME
Nucleolar GTP-binding protein 1
Search

0.72	Nucleolar GTP-binding protein 1

0.63	GO:0042254	ribosome biogenesis
0.47	GO:0090307	mitotic spindle assembly
0.34	GO:0051301	cell division

0.66	GO:0001883	purine nucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V412|U428_DROME
UPF0428 protein CG16865
Search

0.68

GO:0000398

mRNA splicing, via spliceosome

0.49

GO:0016846

carbon-sulfur lyase activity

0.74	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0044425	membrane part

0.49

EC:4.4

GO:0016846

tr|Q9V414|Q9V414_DROME
LD36341p
Search

0.83	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.56	GO:0016246	RNA interference
0.55	GO:0035195	gene silencing by miRNA
0.49	GO:0007004	telomere maintenance via telomerase
0.48	GO:0043487	regulation of RNA stability
0.47	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.45	GO:0051028	mRNA transport
0.45	GO:0006405	RNA export from nucleus
0.43	GO:0090501	RNA phosphodiester bond hydrolysis
0.38	GO:0010467	gene expression

0.49	GO:0070034	telomerase RNA binding
0.47	GO:0042162	telomeric DNA binding
0.44	GO:0043021	ribonucleoprotein complex binding
0.43	GO:0004540	ribonuclease activity

0.49	GO:0005697	telomerase holoenzyme complex
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q9V415|Q9V415_DROME
Hrd3, isoform A
Search

0.80	HMG-coA reductase degradation 3, isoform A

0.51	GO:1903513	endoplasmic reticulum to cytosol transport
0.51	GO:0032527	protein exit from endoplasmic reticulum
0.50	GO:0036503	ERAD pathway
0.49	GO:0006641	triglyceride metabolic process
0.45	GO:0009306	protein secretion
0.38	GO:0007219	Notch signaling pathway
0.36	GO:0045746	negative regulation of Notch signaling pathway
0.35	GO:1904380	endoplasmic reticulum mannose trimming
0.34	GO:0050821	protein stabilization
0.34	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.34	GO:0008800	beta-lactamase activity
0.34	GO:0005515	protein binding
0.33	GO:0032217	riboflavin transmembrane transporter activity
0.32	GO:0036402	proteasome-activating ATPase activity
0.32	GO:0004252	serine-type endopeptidase activity
0.31	GO:0016740	transferase activity

0.51	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex
0.51	GO:0036513	Derlin-1 retrotranslocation complex
0.35	GO:0044322	endoplasmic reticulum quality control compartment
0.35	GO:0031410	cytoplasmic vesicle
0.32	GO:0005887	integral component of plasma membrane

0.34

EC:3.5.2.6

GO:0008800

tr|Q9V416|Q9V416_DROME
Anoctamin
Search

0.42

Anoctamin

0.40	GO:0007316	pole plasm RNA localization
0.39	GO:0007293	germarium-derived egg chamber formation
0.39	GO:0007076	mitotic chromosome condensation
0.38	GO:0045727	positive regulation of translation
0.38	GO:1902476	chloride transmembrane transport
0.36	GO:0008104	protein localization
0.35	GO:0098655	cation transmembrane transport
0.34	GO:0006508	proteolysis
0.32	GO:0006275	regulation of DNA replication
0.32	GO:0045893	positive regulation of transcription, DNA-templated

0.40	GO:0061778	intracellular chloride channel activity
0.39	GO:0003730	mRNA 3'-UTR binding
0.39	GO:0005227	calcium activated cation channel activity
0.38	GO:0004004	ATP-dependent RNA helicase activity
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003688	DNA replication origin binding
0.31	GO:0046872	metal ion binding

0.40	GO:0045170	spectrosome
0.39	GO:0043186	P granule
0.38	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005886	plasma membrane
0.32	GO:0042025	host cell nucleus
0.30	GO:0016021	integral component of membrane

0.34

GO:0004252

sp|Q9V419|C28A5_DROME
Probable cytochrome P450 28a5
Search

0.53	GO:0055114	oxidation-reduction process
0.32	GO:1900561	dehydroaustinol metabolic process
0.32	GO:1900558	austinol metabolic process
0.32	GO:0032259	methylation
0.32	GO:0044550	secondary metabolite biosynthetic process
0.32	GO:0016114	terpenoid biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0008168	methyltransferase activity

0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|Q9V420|Q9V420_DROME
FI02878p
Search

0.82	prostaglandin E synthase 2

0.68	GO:0045454	cell redox homeostasis
0.60	GO:0022900	electron transport chain
0.35	GO:0071929	alpha-tubulin acetylation
0.35	GO:0070507	regulation of microtubule cytoskeleton organization
0.34	GO:0048666	neuron development

0.85	GO:0050220	prostaglandin-E synthase activity
0.71	GO:0015035	protein disulfide oxidoreductase activity
0.62	GO:0009055	electron transfer activity
0.37	GO:0016740	transferase activity
0.33	GO:0003723	RNA binding
0.32	GO:0070403	NAD+ binding

0.34	GO:0005874	microtubule
0.30	GO:0016020	membrane

0.85	EC:5.3.99.3	GO:0050220
0.85	KEGG:R02265	GO:0050220

tr|Q9V421|Q9V421_DROME
Metalloendopeptidase
Search

0.59	Metalloendopeptidase

0.59	GO:0006508	proteolysis
0.43	GO:0018996	molting cycle, collagen and cuticulin-based cuticle

0.68	GO:0004222	metalloendopeptidase activity
0.61	GO:0008270	zinc ion binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004222

sp|Q9V422|RYK2_DROME
Tyrosine-protein kinase Dnt
Search

RYK

0.57	Tyrosine-protein kinase Dnt

0.63	GO:0006468	protein phosphorylation
0.54	GO:0016204	determination of muscle attachment site
0.53	GO:0007411	axon guidance
0.51	GO:0007435	salivary gland morphogenesis
0.48	GO:0018212	peptidyl-tyrosine modification
0.44	GO:0048843	negative regulation of axon extension involved in axon guidance
0.44	GO:1904948	midbrain dopaminergic neuron differentiation
0.44	GO:0022038	corpus callosum development
0.44	GO:0007165	signal transduction
0.43	GO:0050919	negative chemotaxis

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0046982	protein heterodimerization activity
0.43	GO:0017147	Wnt-protein binding
0.43	GO:0005109	frizzled binding
0.43	GO:0042813	Wnt-activated receptor activity
0.32	GO:0016791	phosphatase activity

0.49	GO:0043235	receptor complex
0.37	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.32

GO:0016791

tr|Q9V426|Q9V426_DROME
LD07162p
Search

0.63	ribosome-binding protein 1

0.79	GO:0070828	heterochromatin organization
0.77	GO:0016246	RNA interference
0.44	GO:0070417	cellular response to cold
0.44	GO:0051567	histone H3-K9 methylation
0.43	GO:0000027	ribosomal large subunit assembly
0.42	GO:0031935	regulation of chromatin silencing
0.42	GO:0006401	RNA catabolic process
0.38	GO:0006413	translational initiation
0.34	GO:0006886	intracellular protein transport
0.34	GO:0016192	vesicle-mediated transport

0.44	GO:0003729	mRNA binding
0.43	GO:0008186	RNA-dependent ATPase activity
0.43	GO:0003724	RNA helicase activity
0.41	GO:0070035	purine NTP-dependent helicase activity
0.38	GO:0003743	translation initiation factor activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008144	drug binding
0.36	GO:0004427	inorganic diphosphatase activity
0.35	GO:0070008	serine-type exopeptidase activity

0.81	GO:0005703	polytene chromosome puff
0.78	GO:0016442	RISC complex
0.57	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.44	GO:0005701	polytene chromosome chromocenter
0.35	GO:0048475	coated membrane
0.33	GO:0098796	membrane protein complex

0.43	EC:2.7.7	GO:0003724
0.36	KEGG:R00004	GO:0004427

sp|Q9V427|INX2_DROME
Innexin inx2
Search

INX

0.66

Innexin

0.59	GO:0006811	ion transport
0.47	GO:0036098	male germ-line stem cell population maintenance
0.46	GO:0010496	intercellular transport
0.46	GO:0030727	germarium-derived female germ-line cyst formation
0.46	GO:0007440	foregut morphogenesis
0.44	GO:0016331	morphogenesis of embryonic epithelium
0.44	GO:0007283	spermatogenesis
0.38	GO:0007154	cell communication
0.37	GO:0055085	transmembrane transport
0.31	GO:0055114	oxidation-reduction process

0.47	GO:0005243	gap junction channel activity
0.32	GO:0016491	oxidoreductase activity

0.81	GO:0005921	gap junction
0.56	GO:0005886	plasma membrane
0.44	GO:0045177	apical part of cell
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.32

GO:0016491

tr|Q9V428|Q9V428_DROME
Icarus, isoform A
Search

0.49	ras suppressor protein 1

0.84	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.84	GO:0043508	negative regulation of JUN kinase activity
0.74	GO:0007229	integrin-mediated signaling pathway
0.39	GO:0045087	innate immune response
0.39	GO:0006470	protein dephosphorylation
0.37	GO:0006281	DNA repair
0.34	GO:0055114	oxidation-reduction process

0.39	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0003677	DNA binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016491	oxidoreductase activity

0.30

GO:0016020

membrane

0.39

GO:0004721

sp|Q9V429|THIO2_DROME
Thioredoxin-2
Search

0.48	Thioredoxin

0.75	GO:0006662	glycerol ether metabolic process
0.69	GO:0045454	cell redox homeostasis
0.52	GO:0055114	oxidation-reduction process
0.38	GO:0034599	cellular response to oxidative stress
0.37	GO:0098869	cellular oxidant detoxification
0.36	GO:0008340	determination of adult lifespan
0.36	GO:0050832	defense response to fungus
0.33	GO:0051276	chromosome organization
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:2001141	regulation of RNA biosynthetic process

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.39	GO:0047134	protein-disulfide reductase activity
0.38	GO:0004791	thioredoxin-disulfide reductase activity
0.38	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome

0.39	EC:1.8.1.8	GO:0047134
0.38	KEGG:R02016	GO:0004791

tr|Q9V430|Q9V430_DROME
IP22191p
Search

0.34	GO:0006470	protein dephosphorylation
0.32	GO:0045087	innate immune response
0.32	GO:0007165	signal transduction

0.34

GO:0004721

phosphoprotein phosphatase activity

0.39

GO:0005887

integral component of plasma membrane

0.34

GO:0004721

sp|Q9V431|API5_DROME
Apoptosis inhibitor 5 homolog
Search

API5

0.84	Apoptosis inhibitor

0.77	GO:0043066	negative regulation of apoptotic process
0.66	GO:2000269	regulation of fibroblast apoptotic process
0.46	GO:0006915	apoptotic process

0.67	GO:0017134	fibroblast growth factor binding
0.36	GO:0003723	RNA binding

0.63	GO:0016607	nuclear speck
0.58	GO:0005681	spliceosomal complex
0.35	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|Q9V433|Q9V433_DROME
DNA helicase RECQE
Search

0.31	DNA helicase RECQE

0.65	GO:0006310	DNA recombination
0.53	GO:0010165	response to X-ray
0.53	GO:0045002	double-strand break repair via single-strand annealing
0.50	GO:0000070	mitotic sister chromatid segregation
0.50	GO:0045930	negative regulation of mitotic cell cycle
0.47	GO:0032392	DNA geometric change
0.41	GO:0045950	negative regulation of mitotic recombination
0.35	GO:0070407	oxidation-dependent protein catabolic process
0.35	GO:0090296	regulation of mitochondrial DNA replication
0.35	GO:0051131	chaperone-mediated protein complex assembly

0.70	GO:0070035	purine NTP-dependent helicase activity
0.63	GO:0042623	ATPase activity, coupled
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.47	GO:0003678	DNA helicase activity
0.45	GO:0003924	GTPase activity
0.44	GO:0032550	purine ribonucleoside binding
0.44	GO:0019001	guanyl nucleotide binding

0.51	GO:0005634	nucleus
0.36	GO:0005694	chromosome
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.1.1.43

GO:0018024

tr|Q9V434|Q9V434_DROME
Asparaginyl-tRNA synthetase, isoform A
Search

0.51	Asparaginyl-tRNA synthetase

0.80	GO:0006421	asparaginyl-tRNA aminoacylation
0.36	GO:0006260	DNA replication
0.35	GO:0006281	DNA repair
0.34	GO:0006783	heme biosynthetic process
0.34	GO:0042357	thiamine diphosphate metabolic process
0.33	GO:0006772	thiamine metabolic process
0.33	GO:0032392	DNA geometric change
0.33	GO:0072528	pyrimidine-containing compound biosynthetic process
0.33	GO:0044272	sulfur compound biosynthetic process
0.33	GO:0006310	DNA recombination

0.80	GO:0004816	asparagine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0017108	5'-flap endonuclease activity
0.35	GO:0004325	ferrochelatase activity
0.34	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.34	GO:0004788	thiamine diphosphokinase activity
0.33	GO:1901681	sulfur compound binding

0.49	GO:0005737	cytoplasm
0.37	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0044427	chromosomal part
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043234	protein complex
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:6.1.1.22	GO:0004816
0.80	KEGG:R03648	GO:0004816

tr|Q9V435|Q9V435_DROME
Yuri gagarin, isoform B
Search

LOC108098441

0.88	centromere-associated protein E isoform X2

0.87	GO:0032053	ciliary basal body organization
0.86	GO:0042332	gravitaxis
0.86	GO:0007291	sperm individualization
0.34	GO:2000845	positive regulation of testosterone secretion
0.34	GO:0032275	luteinizing hormone secretion
0.34	GO:0033327	Leydig cell differentiation
0.34	GO:0001675	acrosome assembly
0.34	GO:0007289	spermatid nucleus differentiation
0.33	GO:0030317	flagellated sperm motility
0.33	GO:0001819	positive regulation of cytokine production

0.33

GO:0003779

actin binding

0.88	GO:0070865	investment cone
0.85	GO:0016529	sarcoplasmic reticulum
0.76	GO:0005635	nuclear envelope
0.33	GO:0005794	Golgi apparatus

tr|Q9V436|Q9V436_DROME
26S proteasome regulatory complex subunit p30
Search

0.66	26S proteasome non-ATPase regulatory subunit

0.61	GO:0006508	proteolysis
0.48	GO:1903955	positive regulation of protein targeting to mitochondrion
0.46	GO:0043632	modification-dependent macromolecule catabolic process
0.46	GO:0044257	cellular protein catabolic process
0.46	GO:0031647	regulation of protein stability
0.44	GO:0043248	proteasome assembly
0.39	GO:0009405	pathogenesis
0.35	GO:0008063	Toll signaling pathway
0.35	GO:0007623	circadian rhythm
0.34	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.40

GO:0090729

toxin activity

0.81	GO:0005838	proteasome regulatory particle
0.40	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|Q9V437|Q9V437_DROME
LD21120p
Search

0.59	Pre-mrna processing factor

0.74	GO:0008380	RNA splicing
0.44	GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription
0.40	GO:0022618	ribonucleoprotein complex assembly
0.39	GO:0006397	mRNA processing
0.34	GO:0006270	DNA replication initiation

0.43	GO:0000386	second spliceosomal transesterification activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0005681	spliceosomal complex
0.42	GO:0005682	U5 snRNP
0.41	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.35	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V438|PDIA6_DROME
Protein disulfide-isomerase A6 homolog
Search

0.40	Thioredoxin/protein disulfide isomerase

0.69	GO:0045454	cell redox homeostasis
0.49	GO:2000427	positive regulation of apoptotic cell clearance
0.39	GO:0006909	phagocytosis
0.39	GO:0034976	response to endoplasmic reticulum stress
0.37	GO:0006457	protein folding
0.32	GO:0055114	oxidation-reduction process

0.63	GO:0016853	isomerase activity
0.36	GO:0033741	adenylyl-sulfate reductase (glutathione) activity
0.36	GO:0140096	catalytic activity, acting on a protein

0.44	GO:0005783	endoplasmic reticulum
0.35	GO:0043233	organelle lumen
0.35	GO:0009986	cell surface
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.63	EC:5	GO:0016853
0.36	KEGG:R05717	GO:0033741

sp|Q9V439|MED22_DROME
Mediator of RNA polymerase II transcription subunit 22
Search

MED22

0.75	Mediator of RNA polymerase II transcription subunit

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0007406	negative regulation of neuroblast proliferation
0.39	GO:0007283	spermatogenesis
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0000278	mitotic cell cycle

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.38	GO:0005730	nucleolus
0.38	GO:0000785	chromatin

tr|Q9V444|Q9V444_DROME
Chromatin accessibility complex 14kD protein
Search

POLE3

0.69	DNA polymerase epsilon subunit

0.53	GO:0016573	histone acetylation
0.49	GO:0034080	CENP-A containing nucleosome assembly
0.49	GO:0071480	cellular response to gamma radiation
0.48	GO:0042766	nucleosome mobilization
0.41	GO:0006974	cellular response to DNA damage stimulus
0.36	GO:0071897	DNA biosynthetic process
0.35	GO:0032201	telomere maintenance via semi-conservative replication
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.33	GO:0006270	DNA replication initiation
0.32	GO:0016310	phosphorylation

0.74	GO:0046982	protein heterodimerization activity
0.46	GO:0004402	histone acetyltransferase activity
0.37	GO:0003887	DNA-directed DNA polymerase activity
0.36	GO:0070615	nucleosome-dependent ATPase activity
0.34	GO:0003677	DNA binding
0.34	GO:0031491	nucleosome binding
0.33	GO:0004386	helicase activity
0.32	GO:0016301	kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0052689	carboxylic ester hydrolase activity

0.60	GO:0005634	nucleus
0.52	GO:0031248	protein acetyltransferase complex
0.49	GO:0044427	chromosomal part
0.48	GO:0031974	membrane-enclosed lumen
0.46	GO:0042575	DNA polymerase complex
0.44	GO:0043234	protein complex
0.42	GO:1904949	ATPase complex
0.32	GO:0005576	extracellular region

0.46	EC:2.3.1.48	GO:0004402
0.32	KEGG:R00630	GO:0052689

tr|Q9V445|Q9V445_DROME
Metalloendopeptidase
Search

0.58	Metalloendopeptidase

0.60	GO:0006508	proteolysis
0.37	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.35	GO:0016477	cell migration
0.34	GO:0051604	protein maturation

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding

0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

sp|Q9V447|KRH2_DROME
Krueppel homolog 2
Search

0.46	Transmembrane protein 33

0.52	GO:1903896	positive regulation of IRE1-mediated unfolded protein response
0.52	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.52	GO:1903371	regulation of endoplasmic reticulum tubular network organization
0.47	GO:0034976	response to endoplasmic reticulum stress
0.47	GO:0051292	nuclear pore complex assembly
0.47	GO:0071786	endoplasmic reticulum tubular network organization
0.41	GO:0034613	cellular protein localization
0.35	GO:0006457	protein folding
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.45	GO:0017056	structural constituent of nuclear pore
0.36	GO:0051082	unfolded protein binding
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003723	RNA binding

0.49	GO:0042470	melanosome
0.48	GO:0005635	nuclear envelope
0.47	GO:0030176	integral component of endoplasmic reticulum membrane
0.39	GO:0043234	protein complex
0.35	GO:0070062	extracellular exosome

tr|Q9V449|Q9V449_DROME
MET75Ca protein
Search

0.77

GO:0032504

multicellular organism reproduction

0.73

GO:0005615

extracellular space

tr|Q9V451|Q9V451_DROME
Mst85C, isoform A
Search

tr|Q9V452|Q9V452_DROME
Chromatin accessibility complex 16kD protein, isoform A
Search

CHRC1

0.75	chromatin accessibility complex protein 1

0.64	GO:0042766	nucleosome mobilization
0.37	GO:0001503	ossification
0.36	GO:0007155	cell adhesion
0.35	GO:0000055	ribosomal large subunit export from nucleus
0.34	GO:0042273	ribosomal large subunit biogenesis
0.34	GO:0030036	actin cytoskeleton organization
0.34	GO:0007059	chromosome segregation
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.73	GO:0046982	protein heterodimerization activity
0.42	GO:0070615	nucleosome-dependent ATPase activity
0.36	GO:0042393	histone binding
0.34	GO:0005524	ATP binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0003677	DNA binding

0.66	GO:0008623	CHRAC
0.37	GO:0016514	SWI/SNF complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q9V453|Q9V453_DROME
CG3491
Search

LOC108100989

0.54	RING/FYVE/PHD zinc finger superfamily protein

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.33	GO:0050727	regulation of inflammatory response

0.42	GO:0046872	metal ion binding
0.34	GO:0004386	helicase activity

0.30

GO:0044425

membrane part

tr|Q9V455|Q9V455_DROME
Importin subunit alpha
Search

0.61	Importin subunit alpha

0.80	GO:0006606	protein import into nucleus
0.46	GO:0009411	response to UV
0.37	GO:0042542	response to hydrogen peroxide

0.83	GO:0061608	nuclear import signal receptor activity
0.69	GO:0008565	protein transporter activity
0.48	GO:0005112	Notch binding
0.47	GO:0017022	myosin binding
0.42	GO:0008139	nuclear localization sequence binding
0.38	GO:0008022	protein C-terminus binding
0.33	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.39	GO:0012505	endomembrane system
0.38	GO:0031967	organelle envelope
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0043234	protein complex
0.35	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q9V457|Q9V457_DROME
BIP1 protein
Search

0.86

GO:0035167

larval lymph gland hemopoiesis

0.87	GO:0031208	POZ domain binding
0.45	GO:0003676	nucleic acid binding

0.34

GO:0005634

nucleus

tr|Q9V458|Q9V458_DROME
FI08601p
Search

0.30

GO:0044425

membrane part

tr|Q9V459|Q9V459_DROME
EG:BACR43E12.7 protein
Search

0.10	activating signal cointegrator 1 complex subunit 2 homolog

0.44	GO:0006030	chitin metabolic process
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0007155	cell adhesion
0.41	GO:0007399	nervous system development
0.41	GO:0000272	polysaccharide catabolic process
0.40	GO:0030154	cell differentiation
0.39	GO:0055114	oxidation-reduction process
0.39	GO:0006508	proteolysis
0.39	GO:0045491	xylan metabolic process
0.39	GO:0006351	transcription, DNA-templated

0.46	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.45	GO:0001104	RNA polymerase II transcription cofactor activity
0.43	GO:0008061	chitin binding
0.41	GO:0046872	metal ion binding
0.40	GO:0004175	endopeptidase activity
0.39	GO:0031176	endo-1,4-beta-xylanase activity
0.39	GO:0008236	serine-type peptidase activity
0.39	GO:0005518	collagen binding
0.39	GO:0005272	sodium channel activity
0.37	GO:0004725	protein tyrosine phosphatase activity

0.45	GO:0005576	extracellular region
0.44	GO:0016592	mediator complex
0.37	GO:0005618	cell wall
0.30	GO:0031224	intrinsic component of membrane

0.46

EC:1.13.11

GO:0016702

sp|Q9V460|SPT5H_DROME
Transcription elongation factor SPT5
Search

0.65	Transcription elongation factor SPT5

0.71	GO:0032784	regulation of DNA-templated transcription, elongation
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0006414	translational elongation
0.54	GO:0006351	transcription, DNA-templated
0.52	GO:0007549	dosage compensation
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.37	GO:0006397	mRNA processing
0.32	GO:1902038	positive regulation of hematopoietic stem cell differentiation
0.32	GO:1900364	negative regulation of mRNA polyadenylation

0.57	GO:0003746	translation elongation factor activity
0.51	GO:0000993	RNA polymerase II core binding
0.48	GO:0003729	mRNA binding
0.47	GO:0003682	chromatin binding
0.35	GO:0003677	DNA binding
0.35	GO:0046982	protein heterodimerization activity
0.31	GO:0000339	RNA cap binding
0.31	GO:0003743	translation initiation factor activity

0.57	GO:0005634	nucleus
0.52	GO:0005703	polytene chromosome puff
0.52	GO:0005705	polytene chromosome interband
0.48	GO:0000178	exosome (RNase complex)
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0043234	protein complex
0.36	GO:0000428	DNA-directed RNA polymerase complex
0.31	GO:0016282	eukaryotic 43S preinitiation complex
0.31	GO:0033290	eukaryotic 48S preinitiation complex

sp|Q9V461|MCM6_DROME
DNA replication licensing factor Mcm6
Search

0.43	Zygotic DNA replication licensing factor mcm6-B

0.75	GO:0006270	DNA replication initiation
0.70	GO:0032392	DNA geometric change
0.47	GO:0007307	eggshell chorion gene amplification
0.37	GO:0007049	cell cycle
0.36	GO:0071918	urea transmembrane transport
0.36	GO:0051301	cell division
0.34	GO:0030174	regulation of DNA-dependent DNA replication initiation
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.70	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.45	GO:0070035	purine NTP-dependent helicase activity
0.45	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0015204	urea transmembrane transporter activity
0.34	GO:0046872	metal ion binding

0.79	GO:0042555	MCM complex
0.61	GO:0005634	nucleus
0.44	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|Q9V463|Q9V463_DROME
Nucleoporin 154kD, isoform A
Search

0.61	Nuclear pore complex protein Nup154

0.72	GO:0006913	nucleocytoplasmic transport
0.67	GO:0055049	astral spindle assembly
0.67	GO:0030715	oocyte growth in germarium-derived egg chamber
0.66	GO:1905938	positive regulation of germ cell proliferation
0.66	GO:0036228	protein localization to nuclear inner membrane
0.65	GO:0007053	spindle assembly involved in male meiosis
0.65	GO:0045477	regulation of nurse cell apoptotic process
0.65	GO:0007303	cytoplasmic transport, nurse cell to oocyte
0.63	GO:0030717	karyosome formation
0.60	GO:0042307	positive regulation of protein import into nucleus

0.80	GO:0017056	structural constituent of nuclear pore
0.56	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding
0.35	GO:0004038	allantoinase activity
0.35	GO:0050897	cobalt ion binding
0.33	GO:0015288	porin activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0004386	helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.78	GO:0005643	nuclear pore
0.58	GO:0034399	nuclear periphery
0.51	GO:0005829	cytosol
0.45	GO:0031965	nuclear membrane
0.37	GO:0005694	chromosome
0.33	GO:0046930	pore complex

0.35

EC:3.5.2.5

GO:0004038

sp|Q9V464|ASF1_DROME
Histone chaperone asf1
Search

0.69	Histone chaperone

0.78	GO:0006333	chromatin assembly or disassembly
0.51	GO:0034728	nucleosome organization
0.50	GO:0065004	protein-DNA complex assembly
0.49	GO:0006323	DNA packaging
0.47	GO:0032986	protein-DNA complex disassembly
0.47	GO:0045746	negative regulation of Notch signaling pathway
0.46	GO:0048024	regulation of mRNA splicing, via spliceosome
0.45	GO:0016573	histone acetylation
0.44	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0016311	dephosphorylation

0.47	GO:0001103	RNA polymerase II repressing transcription factor binding
0.46	GO:0042393	histone binding
0.42	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides
0.33	GO:0003910	DNA ligase (ATP) activity
0.33	GO:0004180	carboxypeptidase activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.48	GO:0033186	CAF-1 complex
0.46	GO:0005700	polytene chromosome
0.45	GO:0017053	transcriptional repressor complex
0.39	GO:0044446	intracellular organelle part
0.33	GO:0031974	membrane-enclosed lumen

0.33

EC:6.5.1.1

GO:0003910

tr|Q9V466|Q9V466_DROME
BcDNA.LD18761
Search

0.56	Nuclear pore complex protein Nup107

0.64	GO:0006606	protein import into nucleus
0.62	GO:0007110	meiosis I cytokinesis
0.62	GO:0048137	spermatocyte division
0.61	GO:0000724	double-strand break repair via homologous recombination
0.61	GO:0007112	male meiosis cytokinesis
0.59	GO:0030703	eggshell formation
0.59	GO:0008585	female gonad development
0.58	GO:1900182	positive regulation of protein localization to nucleus
0.53	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.51	GO:0051028	mRNA transport

0.80	GO:0017056	structural constituent of nuclear pore
0.34	GO:0005549	odorant binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005643	nuclear pore
0.51	GO:0000776	kinetochore
0.38	GO:0034399	nuclear periphery
0.38	GO:0031965	nuclear membrane
0.36	GO:0005819	spindle
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9V468|Y9776_DROME
Zinc finger matrin-type protein CG9776
Search

0.89	Zinc finger matrin-type protein CG9776

0.34	GO:0006464	cellular protein modification process
0.33	GO:0016310	phosphorylation
0.33	GO:0035082	axoneme assembly
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0043484	regulation of RNA splicing
0.32	GO:0006396	RNA processing
0.32	GO:0051726	regulation of cell cycle
0.32	GO:0016071	mRNA metabolic process

0.60	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0016853	isomerase activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.40	GO:0005634	nucleus
0.32	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.34

GO:0016853

tr|Q9V470|Q9V470_DROME
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
Search

0.86	Succinate-CoA ligase subunit beta

0.78	GO:0006104	succinyl-CoA metabolic process
0.71	GO:0006099	tricarboxylic acid cycle
0.47	GO:0048085	adult chitin-containing cuticle pigmentation

0.76	GO:0004776	succinate-CoA ligase (GDP-forming) activity
0.74	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.62	GO:0000287	magnesium ion binding
0.57	GO:0032550	purine ribonucleoside binding
0.57	GO:0019001	guanyl nucleotide binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005739	mitochondrion
0.36	GO:0042709	succinate-CoA ligase complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.76	EC:6.2.1.4	GO:0004776
0.76	KEGG:R00432	GO:0004776

tr|Q9V471|Q9V471_DROME
RE54080p
Search

LOC108098440

0.94	zinc transporter 2 isoform X1

0.67	GO:0010312	detoxification of zinc ion
0.62	GO:0006882	cellular zinc ion homeostasis
0.61	GO:0098655	cation transmembrane transport
0.59	GO:0006829	zinc II ion transport
0.48	GO:0098660	inorganic ion transmembrane transport
0.44	GO:0061088	regulation of sequestering of zinc ion
0.36	GO:0043044	ATP-dependent chromatin remodeling
0.35	GO:0016569	covalent chromatin modification
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.66	GO:0022883	zinc efflux transmembrane transporter activity
0.36	GO:0031491	nucleosome binding
0.34	GO:0004386	helicase activity
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0016887	ATPase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0016324	apical plasma membrane
0.40	GO:0031410	cytoplasmic vesicle
0.39	GO:0016323	basolateral plasma membrane
0.36	GO:0016589	NURF complex
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

tr|Q9V472|Q9V472_DROME
DLim1
Search

0.71	Insulin gene enhancer protein ISL-2

0.59	GO:0007479	leg disc proximal/distal pattern formation
0.57	GO:0007480	imaginal disc-derived leg morphogenesis
0.55	GO:0048749	compound eye development
0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.50	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process
0.49	GO:0051253	negative regulation of RNA metabolic process

0.59	GO:0043565	sequence-specific DNA binding
0.50	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.32	GO:0016740	transferase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.58	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016740

tr|Q9V474|Q9V474_DROME
BcDNA.LD26519
Search

0.79

GO:0007616

long-term memory

0.62	GO:0008270	zinc ion binding
0.39	GO:0030246	carbohydrate binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005771	multivesicular body
0.60	GO:0005634	nucleus

sp|Q9V477|TOLL8_DROME
Toll-like receptor Tollo
Search

0.80	Vasorin precursor

0.60	GO:0007165	signal transduction
0.57	GO:0002227	innate immune response in mucosa
0.56	GO:0060049	regulation of protein glycosylation
0.55	GO:0048935	peripheral nervous system neuron development
0.55	GO:0003401	axis elongation
0.54	GO:0060026	convergent extension
0.34	GO:0006470	protein dephosphorylation

0.34

GO:0004721

phosphoprotein phosphatase activity

0.36	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0004721

tr|Q9V481|Q9V481_DROME
Forkhead domain 102C
Search

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.41	GO:0097659	nucleic acid-templated transcription
0.40	GO:0030154	cell differentiation
0.40	GO:0009653	anatomical structure morphogenesis
0.40	GO:0010467	gene expression
0.39	GO:0034645	cellular macromolecule biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0050825	ice binding

0.61

GO:0005634

nucleus

tr|Q9V490|Q9V490_DROME
GH14454p
Search

0.60	Transcription factor Toy

0.69	GO:0007275	multicellular organism development
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0060322	head development
0.53	GO:0060429	epithelium development
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.50	GO:0009653	anatomical structure morphogenesis
0.34	GO:0043524	negative regulation of neuron apoptotic process

0.58	GO:0043565	sequence-specific DNA binding
0.56	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.32	GO:0016491	oxidoreductase activity

0.61

GO:0005634

nucleus

0.32

GO:0016491

tr|Q9V491|Q9V491_DROME
Plexin A, isoform A
Search

PLEXA

0.96	Plexin A [Tribolium castaneum]

0.83	GO:0071526	semaphorin-plexin signaling pathway
0.54	GO:0097374	sensory neuron axon guidance
0.54	GO:2000289	regulation of photoreceptor cell axon guidance
0.52	GO:0016199	axon midline choice point recognition
0.51	GO:0031284	positive regulation of guanylate cyclase activity
0.49	GO:0007265	Ras protein signal transduction
0.47	GO:0043547	positive regulation of GTPase activity
0.45	GO:0008045	motor neuron axon guidance
0.40	GO:0048841	regulation of axon extension involved in axon guidance

0.84	GO:0017154	semaphorin receptor activity
0.52	GO:0010853	cyclase activator activity
0.52	GO:0071889	14-3-3 protein binding
0.52	GO:0030249	guanylate cyclase regulator activity
0.49	GO:0008201	heparin binding
0.47	GO:0005096	GTPase activator activity

0.39	GO:0005887	integral component of plasma membrane
0.36	GO:0005622	intracellular

sp|Q9V492|MPV17_DROME
Mpv17-like protein
Search

0.11	Integral membrane mpv17 pmp22

0.46	GO:0006067	ethanol metabolic process
0.42	GO:0000002	mitochondrial genome maintenance
0.42	GO:0034614	cellular response to reactive oxygen species
0.39	GO:0042592	homeostatic process

0.43	GO:0005739	mitochondrion
0.42	GO:0019866	organelle inner membrane
0.41	GO:0005778	peroxisomal membrane
0.30	GO:0044425	membrane part

tr|Q9V493|Q9V493_DROME
GM15303p
Search

sp|Q9V496|APLP_DROME
Apolipophorins
Search

0.73	Apolipophorins

0.74	GO:0006869	lipid transport
0.66	GO:0045880	positive regulation of smoothened signaling pathway
0.64	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.41	GO:0016055	Wnt signaling pathway
0.37	GO:0016192	vesicle-mediated transport
0.34	GO:0007605	sensory perception of sound
0.34	GO:0006836	neurotransmitter transport
0.32	GO:0055085	transmembrane transport

0.77	GO:0005319	lipid transporter activity
0.68	GO:0019841	retinol binding
0.65	GO:0005504	fatty acid binding
0.57	GO:0008017	microtubule binding
0.56	GO:0005102	receptor binding
0.50	GO:0020037	heme binding
0.36	GO:0046872	metal ion binding
0.34	GO:0005328	neurotransmitter:sodium symporter activity

0.65	GO:0045178	basal part of cell
0.62	GO:0030139	endocytic vesicle
0.57	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|Q9V498|CSTN1_DROME
Calsyntenin-1
Search

0.71	Calsyntenin-1

0.76	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.43	GO:0051965	positive regulation of synapse assembly
0.43	GO:0050806	positive regulation of synaptic transmission
0.42	GO:0001558	regulation of cell growth
0.38	GO:0044331	cell-cell adhesion mediated by cadherin
0.38	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.35	GO:1990126	retrograde transport, endosome to plasma membrane
0.35	GO:0051609	inhibition of neurotransmitter uptake
0.35	GO:0050770	regulation of axonogenesis
0.34	GO:0008361	regulation of cell size

0.70	GO:0005509	calcium ion binding
0.45	GO:0042988	X11-like protein binding
0.43	GO:0001540	amyloid-beta binding
0.43	GO:0019894	kinesin binding
0.37	GO:0008013	beta-catenin binding
0.34	GO:0090729	toxin activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0003735	structural constituent of ribosome

0.43	GO:0045211	postsynaptic membrane
0.42	GO:0014069	postsynaptic density
0.41	GO:0009986	cell surface
0.40	GO:0005576	extracellular region
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0030054	cell junction
0.33	GO:0000139	Golgi membrane
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0031982	vesicle
0.32	GO:0042995	cell projection

0.33

GO:0004222

tr|Q9V4A0|Q9V4A0_DROME
FI01405p
Search

0.71	Glutamate receptor ionotropic, kainate

0.78	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.58	GO:0006811	ion transport
0.51	GO:0055085	transmembrane transport
0.47	GO:0016057	regulation of membrane potential in photoreceptor cell
0.47	GO:0071632	optomotor response
0.46	GO:0071484	cellular response to light intensity
0.45	GO:0035249	synaptic transmission, glutamatergic
0.45	GO:0060025	regulation of synaptic activity

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.42	GO:0099094	ligand-gated cation channel activity
0.42	GO:0005272	sodium channel activity
0.41	GO:0098782	mechanosensitived potassium channel activity

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|Q9V4A1|Q9V4A1_DROME
Kinesin-like protein
Search

sp|Q9V4A7|PLXB_DROME
Plexin-B
Search

0.77	Putative plexins functional semaphorin receptor

0.83	GO:0071526	semaphorin-plexin signaling pathway
0.60	GO:0071678	olfactory bulb axon guidance
0.59	GO:0097374	sensory neuron axon guidance
0.59	GO:0070593	dendrite self-avoidance
0.57	GO:0008045	motor neuron axon guidance
0.42	GO:0043087	regulation of GTPase activity
0.41	GO:0050772	positive regulation of axonogenesis
0.40	GO:0007162	negative regulation of cell adhesion
0.39	GO:0035021	negative regulation of Rac protein signal transduction
0.39	GO:0035025	positive regulation of Rho protein signal transduction

0.84	GO:0017154	semaphorin receptor activity
0.35	GO:0005515	protein binding

0.54	GO:0030425	dendrite
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q9V4B6|Q9V4B6_DROME
Uncharacterized protein, isoform A
Search

0.33	GO:0016310	phosphorylation
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.34	GO:0016301	kinase activity

0.30

GO:0031224

intrinsic component of membrane

0.34

EC:1.1.1

GO:0016616

tr|Q9V4B8|Q9V4B8_DROME
RE68558p
Search

0.47	Putative latent-transforming growth factor beta-binding protein 4

0.48	GO:0006030	chitin metabolic process
0.38	GO:0090287	regulation of cellular response to growth factor stimulus
0.38	GO:0071694	maintenance of protein location in extracellular region
0.38	GO:0035581	sequestering of extracellular ligand from receptor
0.37	GO:0060346	bone trabecula formation
0.37	GO:0030501	positive regulation of bone mineralization
0.37	GO:0030198	extracellular matrix organization
0.37	GO:0006334	nucleosome assembly
0.37	GO:0048048	embryonic eye morphogenesis
0.37	GO:0045669	positive regulation of osteoblast differentiation

0.70	GO:0005509	calcium ion binding
0.53	GO:0005201	extracellular matrix structural constituent
0.48	GO:0008061	chitin binding
0.35	GO:0016504	peptidase activator activity
0.33	GO:0099600	transmembrane receptor activity
0.33	GO:0003677	DNA binding
0.33	GO:0038023	signaling receptor activity
0.33	GO:0004447	iodide peroxidase activity
0.32	GO:0004713	protein tyrosine kinase activity
0.31	GO:0016787	hydrolase activity

0.52	GO:0005576	extracellular region
0.35	GO:0099512	supramolecular fiber
0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

EC:1.11.1.8

GO:0004447

tr|Q9V4C0|Q9V4C0_DROME
Yellow-h
Search

0.80

Yellow-h

0.65	GO:0042438	melanin biosynthetic process
0.58	GO:0060179	male mating behavior
0.53	GO:0048067	cuticle pigmentation
0.39	GO:0035725	sodium ion transmembrane transport
0.39	GO:0000413	protein peptidyl-prolyl isomerization

0.40	GO:0005272	sodium channel activity
0.39	GO:0016853	isomerase activity
0.36	GO:0140096	catalytic activity, acting on a protein

0.30

GO:0016020

membrane

0.39

GO:0016853

tr|Q9V4C4|Q9V4C4_DROME
Synaptotagmin 7, isoform A
Search

0.83	Synaptotagmin VIIa

0.76	GO:0006887	exocytosis
0.45	GO:0099643	signal release from synapse
0.45	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.43	GO:0006836	neurotransmitter transport
0.42	GO:0001505	regulation of neurotransmitter levels
0.42	GO:0048489	synaptic vesicle transport
0.42	GO:0099504	synaptic vesicle cycle
0.40	GO:0017158	regulation of calcium ion-dependent exocytosis
0.40	GO:0006906	vesicle fusion
0.36	GO:0090119	vesicle-mediated cholesterol transport

0.81	GO:0005544	calcium-dependent phospholipid binding
0.40	GO:0000149	SNARE binding
0.38	GO:0030276	clathrin binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0001786	phosphatidylserine binding
0.35	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0005516	calmodulin binding
0.32	GO:0005319	lipid transporter activity
0.31	GO:0003676	nucleic acid binding

0.50	GO:0016528	sarcoplasm
0.48	GO:0005764	lysosome
0.47	GO:0031982	vesicle
0.44	GO:0098793	presynapse
0.39	GO:0012505	endomembrane system
0.35	GO:0044306	neuron projection terminus
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0005886	plasma membrane
0.35	GO:0005777	peroxisome

tr|Q9V4C6|Q9V4C6_DROME
Zinc/iron regulated transporter-related protein 102B, isoform E
Search

0.50	Zinc transporter

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.33	GO:0006629	lipid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.69	GO:0046873	metal ion transmembrane transporter activity
0.35	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.35	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0003676	nucleic acid binding

0.30

GO:0044425

membrane part

sp|Q9V4C8|HCF_DROME
Host cell factor
Search

0.71	Host cell factor

0.51	GO:0043967	histone H4 acetylation
0.50	GO:0043966	histone H3 acetylation
0.49	GO:0045927	positive regulation of growth
0.47	GO:0006338	chromatin remodeling
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0019045	latent virus replication
0.39	GO:0051568	histone H3-K4 methylation
0.38	GO:0050821	protein stabilization
0.37	GO:0006366	transcription by RNA polymerase II
0.37	GO:0006357	regulation of transcription by RNA polymerase II

0.50	GO:0004402	histone acetyltransferase activity
0.49	GO:0003682	chromatin binding
0.41	GO:0003713	transcription coactivator activity
0.39	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.38	GO:0033613	activating transcription factor binding
0.38	GO:0045296	cadherin binding
0.37	GO:0030674	protein binding, bridging
0.37	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.81	GO:0048188	Set1C/COMPASS complex
0.52	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.50	GO:0044666	MLL3/4 complex
0.38	GO:0043025	neuronal cell body
0.37	GO:0070461	SAGA-type complex
0.33	GO:0005737	cytoplasm

0.50

GO:0004402

tr|Q9V4D4|Q9V4D4_DROME
Bip2
Search

0.62	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0006413	translational initiation
0.32	GO:0032259	methylation

0.75	GO:0031208	POZ domain binding
0.70	GO:0046982	protein heterodimerization activity
0.69	GO:0002039	p53 binding
0.63	GO:0003682	chromatin binding
0.60	GO:0008134	transcription factor binding
0.50	GO:0046872	metal ion binding
0.43	GO:0003743	translation initiation factor activity
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.71	GO:0005669	transcription factor TFIID complex
0.30	GO:0016020	membrane

0.32

GO:0008168

tr|Q9V4D8|Q9V4D8_DROME
FI14922p
Search

0.65	GO:0006281	DNA repair
0.53	GO:1902544	regulation of DNA N-glycosylase activity
0.52	GO:0035562	negative regulation of chromatin binding
0.50	GO:0032091	negative regulation of protein binding
0.49	GO:0080111	DNA demethylation
0.48	GO:0040029	regulation of gene expression, epigenetic
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0009790	embryo development
0.37	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.35	GO:0016569	covalent chromatin modification

0.74	GO:0019104	DNA N-glycosylase activity
0.51	GO:0031404	chloride ion binding
0.51	GO:0032183	SUMO binding
0.51	GO:0005080	protein kinase C binding
0.51	GO:0003690	double-stranded DNA binding
0.50	GO:0043621	protein self-association
0.49	GO:0031402	sodium ion binding
0.47	GO:0001104	RNA polymerase II transcription cofactor activity
0.46	GO:0042803	protein homodimerization activity
0.43	GO:0000287	magnesium ion binding

0.50	GO:0016605	PML body
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74

EC:3.2.2

GO:0019104

tr|Q9V4D9|Q9V4D9_DROME
Purine-rich binding protein-alpha, isoform B
Search

0.75	Transcriptional activator protein Pur-alpha

0.72

GO:0031935

regulation of chromatin silencing

0.65	GO:0003729	mRNA binding
0.57	GO:0043565	sequence-specific DNA binding
0.39	GO:0042802	identical protein binding
0.38	GO:0004019	adenylosuccinate synthase activity

0.77	GO:1990124	messenger ribonucleoprotein complex
0.54	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:6.3.4.4	GO:0004019
0.38	KEGG:R01135	GO:0004019

tr|Q9V4E0|Q9V4E0_DROME
LD47962p
Search

0.74	Mitochondrial NADH dehydrogenase iron-sulfur protein 2

0.53	GO:0055114	oxidation-reduction process
0.38	GO:0006979	response to oxidative stress
0.37	GO:0006119	oxidative phosphorylation
0.34	GO:0032981	mitochondrial respiratory chain complex I assembly

0.72	GO:0048038	quinone binding
0.68	GO:0051287	NAD binding
0.67	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.39	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0051539	4 iron, 4 sulfur cluster binding
0.34	GO:0005549	odorant binding
0.33	GO:0046872	metal ion binding
0.33	GO:0004872	receptor activity
0.33	GO:0009055	electron transfer activity

0.41	GO:0005747	mitochondrial respiratory chain complex I
0.37	GO:0005654	nucleoplasm
0.34	GO:0005764	lysosome
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.67

EC:1.6

GO:0016651

tr|Q9V4E1|Q9V4E1_DROME
Ephrin
Search

0.70	Putative ephrin ligand for eph receptor tyrosine kinase (Fragment)

0.62	GO:0035011	melanotic encapsulation of foreign target
0.60	GO:0016319	mushroom body development
0.58	GO:0007422	peripheral nervous system development
0.57	GO:0007411	axon guidance
0.41	GO:0048013	ephrin receptor signaling pathway
0.33	GO:0016310	phosphorylation
0.33	GO:0055085	transmembrane transport

0.60	GO:0046875	ephrin receptor binding
0.33	GO:0016301	kinase activity

0.49

GO:0005887

integral component of plasma membrane

tr|Q9V4E5|Q9V4E5_DROME
Eph receptor tyrosine kinase, isoform C
Search

EPH

0.54	Eph receptor tyrosine kinase

0.82	GO:0048013	ephrin receptor signaling pathway
0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.57	GO:0035011	melanotic encapsulation of foreign target
0.56	GO:0016319	mushroom body development
0.54	GO:0007422	peripheral nervous system development
0.47	GO:0046777	protein autophosphorylation
0.35	GO:0071260	cellular response to mechanical stimulus
0.34	GO:0006836	neurotransmitter transport
0.33	GO:0055085	transmembrane transport

0.84	GO:0005003	ephrin receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005328	neurotransmitter:sodium symporter activity
0.33	GO:0004568	chitinase activity

0.59	GO:0005887	integral component of plasma membrane
0.36	GO:0097386	glial cell projection

0.33

GO:0004568

tr|Q9V4E6|Q9V4E6_DROME
Maverick
Search

0.58	inhibin beta A chain

0.75	GO:0010469	regulation of receptor activity
0.70	GO:0007179	transforming growth factor beta receptor signaling pathway
0.46	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.46	GO:0060395	SMAD protein signal transduction
0.45	GO:0030509	BMP signaling pathway
0.44	GO:0043408	regulation of MAPK cascade
0.43	GO:0048468	cell development
0.43	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.46	GO:0005160	transforming growth factor beta receptor binding
0.44	GO:0005125	cytokine activity

0.74	GO:0043083	synaptic cleft
0.42	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

tr|Q9V4E7|Q9V4E7_DROME
Transporter
Search

0.49	Sodium-and chloride-dependent neurotransmitter transporter (Fragment)

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.48	GO:0071260	cellular response to mechanical stimulus
0.41	GO:0015718	monocarboxylic acid transport
0.40	GO:0006865	amino acid transport
0.38	GO:0007268	chemical synaptic transmission
0.37	GO:0015734	taurine transport
0.35	GO:0048013	ephrin receptor signaling pathway
0.33	GO:0006468	protein phosphorylation
0.32	GO:0006265	DNA topological change

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.44	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.44	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.43	GO:0005343	organic acid:sodium symporter activity
0.43	GO:0015296	anion:cation symporter activity
0.42	GO:0005416	amino acid:cation symporter activity
0.37	GO:0005368	taurine transmembrane transporter activity
0.35	GO:0005003	ephrin receptor activity
0.33	GO:0003917	DNA topoisomerase type I activity
0.33	GO:0003676	nucleic acid binding

0.49	GO:0097386	glial cell projection
0.40	GO:0005886	plasma membrane
0.38	GO:0043005	neuron projection
0.32	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.33

EC:5.99.1.2

GO:0003917

tr|Q9V4F3|Q9V4F3_DROME
LD09246p1
Search

MEX3B

0.89	RING finger and KH domain-containing protein 3 (Fragment)

0.39	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0072697	protein localization to cell cortex
0.36	GO:0050766	positive regulation of phagocytosis
0.35	GO:0022409	positive regulation of cell-cell adhesion
0.35	GO:0043547	positive regulation of GTPase activity
0.35	GO:0046777	protein autophosphorylation

0.59	GO:0003723	RNA binding
0.37	GO:0032794	GTPase activating protein binding
0.36	GO:0008270	zinc ion binding
0.35	GO:0016874	ligase activity
0.34	GO:0005509	calcium ion binding

0.44	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.36	GO:0000932	P-body
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016874

tr|Q9V4F4|Q9V4F4_DROME
LD29161p
Search

0.85	Myoglianin

0.75	GO:0010469	regulation of receptor activity
0.71	GO:0016319	mushroom body development
0.46	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.46	GO:0060395	SMAD protein signal transduction
0.44	GO:0030509	BMP signaling pathway
0.44	GO:0043408	regulation of MAPK cascade
0.43	GO:0048468	cell development
0.43	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.46	GO:0005160	transforming growth factor beta receptor binding
0.44	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q9V4F9|MED26_DROME
Mediator of RNA polymerase II transcription subunit 26
Search

0.10	Mediator of RNA polymerase II transcription subunit 26

0.67	GO:0010628	positive regulation of gene expression
0.66	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0006351	transcription, DNA-templated

0.37

GO:0001104

RNA polymerase II transcription cofactor activity

0.84	GO:0005701	polytene chromosome chromocenter
0.80	GO:0070847	core mediator complex
0.80	GO:0031618	nuclear pericentric heterochromatin
0.68	GO:0005730	nucleolus
0.37	GO:0016592	mediator complex

sp|Q9V4I0|CP9B1_DROME
Cytochrome P450 9b1
Search

0.10	Microsomal cytochrome P450

0.53

GO:0055114

oxidation-reduction process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V4I1|CP9B2_DROME
Cytochrome P450 9b2
Search

0.10	Microsomal cytochrome P450

0.53	GO:0055114	oxidation-reduction process
0.36	GO:0007608	sensory perception of smell

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.39	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V4K2|GR43A_DROME
Gustatory receptor for sugar taste 43a
Search

0.49	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction
0.45	GO:0008049	male courtship behavior
0.43	GO:0010037	response to carbon dioxide
0.42	GO:0007635	chemosensory behavior
0.41	GO:0071332	cellular response to fructose stimulus
0.40	GO:0008343	adult feeding behavior
0.40	GO:0060259	regulation of feeding behavior
0.40	GO:0032098	regulation of appetite
0.40	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.63	GO:0004871	signal transducer activity
0.39	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|Q9V4L4|KBRAS_DROME
NF-kappa-B inhibitor-interacting Ras-like protein
Search

0.84	NF-kappa-B inhibitor-interacting Ras protein isoform 1

0.61	GO:0007165	signal transduction
0.37	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling

0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.34	GO:0005515	protein binding

0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9V4M2|WECH_DROME
Protein wech
Search

0.11

Dappled

0.58	GO:0033632	regulation of cell-cell adhesion mediated by integrin
0.57	GO:0016203	muscle attachment
0.57	GO:0002168	instar larval development
0.48	GO:0061158	3'-UTR-mediated mRNA destabilization
0.47	GO:0035196	production of miRNAs involved in gene silencing by miRNA
0.45	GO:0010586	miRNA metabolic process
0.45	GO:0060964	regulation of gene silencing by miRNA
0.45	GO:0035278	miRNA mediated inhibition of translation
0.44	GO:0048598	embryonic morphogenesis
0.44	GO:0060148	positive regulation of posttranscriptional gene silencing

0.61	GO:0008270	zinc ion binding
0.53	GO:0030674	protein binding, bridging
0.48	GO:0035198	miRNA binding
0.47	GO:0030371	translation repressor activity
0.44	GO:0016874	ligase activity
0.41	GO:0061630	ubiquitin protein ligase activity

0.57	GO:0005927	muscle tendon junction
0.46	GO:0000932	P-body

0.44

GO:0016874

sp|Q9V4N3|CYB5_DROME
Cytochrome b5
Search

CYB5A

0.56	Cytochrome b5A microsomal variant

0.46	GO:0045610	regulation of hemocyte differentiation
0.46	GO:0035206	regulation of hemocyte proliferation
0.39	GO:0055114	oxidation-reduction process
0.37	GO:0042128	nitrate assimilation
0.37	GO:0006809	nitric oxide biosynthetic process
0.36	GO:0046686	response to cadmium ion
0.35	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.34	GO:0072662	protein localization to peroxisome
0.34	GO:0043574	peroxisomal transport
0.34	GO:0005996	monosaccharide metabolic process

0.61	GO:0020037	heme binding
0.52	GO:0046872	metal ion binding
0.42	GO:0019899	enzyme binding
0.38	GO:0016491	oxidoreductase activity
0.37	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0043546	molybdopterin cofactor binding
0.33	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0008047	enzyme activator activity

0.41	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.39	GO:0031090	organelle membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031967	organelle envelope
0.35	GO:0098805	whole membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0019867	outer membrane
0.34	GO:0044438	microbody part
0.33	GO:0005777	peroxisome

0.38	EC:1	GO:0016491
0.33	KEGG:R00955	GO:0008108

sp|Q9V4P1|ANLN_DROME
Anillin
Search

0.60	Actin-binding protein anillin

0.86	GO:0030726	male germline ring canal formation
0.85	GO:0045035	sensory organ precursor cell division
0.85	GO:0007279	pole cell formation
0.83	GO:0007112	male meiosis cytokinesis
0.83	GO:0032189	maintenance of actomyosin contractile ring localization
0.80	GO:0000281	mitotic cytokinesis
0.79	GO:0044837	actomyosin contractile ring organization
0.79	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.78	GO:0031106	septin ring organization
0.77	GO:0007009	plasma membrane organization

0.79	GO:0017022	myosin binding
0.73	GO:0003779	actin binding
0.70	GO:0032403	protein complex binding
0.69	GO:0008017	microtubule binding
0.51	GO:0045296	cadherin binding

0.85	GO:0035323	male germline ring canal
0.84	GO:0005826	actomyosin contractile ring
0.80	GO:0032154	cleavage furrow
0.61	GO:0005634	nucleus
0.56	GO:0032059	bleb
0.52	GO:0099738	cell cortex region
0.52	GO:0030496	midbody
0.46	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V4Q0|Y1339_DROME
Uncharacterized protein CG1339
Search

0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0018108	peptidyl-tyrosine phosphorylation

0.49	GO:0008527	taste receptor activity
0.45	GO:0004930	G-protein coupled receptor activity
0.40	GO:0004713	protein tyrosine kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.40

EC:2.7.10

GO:0004713

sp|Q9V4Q8|RU2A_DROME
Probable U2 small nuclear ribonucleoprotein A'
Search

0.68	U2 small nuclear ribonucleoprotein A'

0.53	GO:0007283	spermatogenesis
0.49	GO:0006325	chromatin organization
0.43	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0000278	mitotic cell cycle
0.36	GO:0001731	formation of translation preinitiation complex
0.36	GO:0006446	regulation of translational initiation
0.34	GO:0006886	intracellular protein transport
0.34	GO:0006629	lipid metabolic process

0.47	GO:0030620	U2 snRNA binding
0.36	GO:0004806	triglyceride lipase activity
0.35	GO:0003743	translation initiation factor activity

0.65	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0120114	Sm-like protein family complex
0.41	GO:0044428	nuclear part
0.37	GO:1902494	catalytic complex
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005852	eukaryotic translation initiation factor 3 complex
0.35	GO:0030176	integral component of endoplasmic reticulum membrane
0.34	GO:0005576	extracellular region

0.36

EC:3.1.1.3

GO:0004806

sp|Q9V4S8|CSN7_DROME
COP9 signalosome complex subunit 7
Search

0.75	COP9 signalosome complex subunit

0.53	GO:0048140	male germ-line cyst encapsulation
0.53	GO:0048142	germarium-derived cystoblast division
0.52	GO:0036099	female germ-line stem cell population maintenance
0.48	GO:0050821	protein stabilization
0.45	GO:0000338	protein deneddylation
0.35	GO:0007275	multicellular organism development
0.34	GO:0006030	chitin metabolic process
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.35	GO:0005515	protein binding
0.34	GO:0008061	chitin binding

0.80	GO:0008180	COP9 signalosome
0.48	GO:0034399	nuclear periphery
0.36	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region

sp|Q9V4T3|C4AD1_DROME
Probable cytochrome P450 4ad1
Search

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0006270	DNA replication initiation
0.33	GO:0032392	DNA geometric change
0.32	GO:0044550	secondary metabolite biosynthetic process
0.32	GO:0055085	transmembrane transport

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0003678	DNA helicase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0008144	drug binding

0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.33	GO:0042555	MCM complex
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q9V4T5|CP4E1_DROME
Probable cytochrome P450 4e1
Search

0.42	Cytochrome P450 monooxygenase CYP4BR7

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0030258	lipid modification
0.32	GO:0006631	fatty acid metabolic process
0.32	GO:0006508	proteolysis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0008236	serine-type peptidase activity

0.41	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.35	GO:0031090	organelle membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V4U7|C6A14_DROME
Probable cytochrome P450 6a14
Search

0.41	p450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.41	GO:0042742	defense response to bacterium
0.41	GO:0048252	lauric acid metabolic process
0.40	GO:0017143	insecticide metabolic process
0.39	GO:0031000	response to caffeine
0.35	GO:0002118	aggressive behavior
0.33	GO:0045892	negative regulation of transcription, DNA-templated
0.32	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0003714	transcription corepressor activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q9V4U9|C6A13_DROME
Probable cytochrome P450 6a13
Search

0.11	Putative cytochrome

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0042742	defense response to bacterium

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.36	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V4W1|GLE1_DROME
Nucleoporin GLE1
Search

0.57	Nucleoporin GLE1

0.83	GO:0016973	poly(A)+ mRNA export from nucleus
0.43	GO:0006449	regulation of translational termination
0.42	GO:0006446	regulation of translational initiation
0.40	GO:0071985	multivesicular body sorting pathway
0.36	GO:0032467	positive regulation of cytokinesis
0.32	GO:0006508	proteolysis

0.45	GO:0000822	inositol hexakisphosphate binding
0.44	GO:0031369	translation initiation factor binding
0.42	GO:0005543	phospholipid binding
0.32	GO:0008234	cysteine-type peptidase activity

0.77	GO:0005643	nuclear pore
0.41	GO:0000814	ESCRT II complex
0.35	GO:0000922	spindle pole
0.35	GO:0005813	centrosome
0.35	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.32

GO:0008234

sp|Q9V4X2|PGSC2_DROME
Peptidoglycan-recognition protein SC2
Search

0.79	Peptidoglycan-recognition protein SC2

0.74	GO:0009253	peptidoglycan catabolic process
0.73	GO:0045087	innate immune response
0.48	GO:0045088	regulation of innate immune response
0.48	GO:0031348	negative regulation of defense response
0.48	GO:0050777	negative regulation of immune response
0.38	GO:0042742	defense response to bacterium
0.37	GO:0019730	antimicrobial humoral response
0.37	GO:0061059	positive regulation of peptidoglycan recognition protein signaling pathway
0.36	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.36	GO:0002757	immune response-activating signal transduction

0.76	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.72	GO:0042834	peptidoglycan binding
0.63	GO:0008270	zinc ion binding
0.38	GO:0016019	peptidoglycan receptor activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0001875	lipopolysaccharide receptor activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.38	GO:0005576	extracellular region
0.36	GO:0016327	apicolateral plasma membrane
0.35	GO:0098793	presynapse
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0089717	spanning component of membrane
0.33	GO:0031314	extrinsic component of mitochondrial inner membrane

0.76

GO:0008745

sp|Q9V4Z9|LINES_DROME
Protein lines
Search

0.11

Lines

0.87	GO:0009946	proximal/distal axis specification
0.86	GO:0048617	embryonic foregut morphogenesis
0.86	GO:0035277	spiracle morphogenesis, open tracheal system
0.86	GO:0007362	terminal region determination
0.86	GO:0008293	torso signaling pathway
0.86	GO:0048619	embryonic hindgut morphogenesis
0.84	GO:0035220	wing disc development
0.82	GO:0008544	epidermis development
0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0007367	segment polarity determination

0.39	GO:0005515	protein binding
0.33	GO:0008168	methyltransferase activity

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

sp|Q9V521|PPO2_DROME
Phenoloxidase 2
Search

0.85	Prophenoloxidase-II

0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035011	melanotic encapsulation of foreign target
0.46	GO:0050830	defense response to Gram-positive bacterium
0.45	GO:0050832	defense response to fungus
0.39	GO:0042438	melanin biosynthetic process
0.37	GO:0042417	dopamine metabolic process
0.34	GO:0006570	tyrosine metabolic process
0.33	GO:0006508	proteolysis

0.53	GO:0016491	oxidoreductase activity
0.53	GO:0046872	metal ion binding
0.35	GO:0008241	peptidyl-dipeptidase activity
0.34	GO:0008237	metallopeptidase activity
0.32	GO:0004180	carboxypeptidase activity

0.43	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0016491

sp|Q9V535|RBM8A_DROME
RNA-binding protein 8A
Search

0.89	RNA-binding protein 8A

0.76	GO:0051028	mRNA transport
0.73	GO:0008380	RNA splicing
0.70	GO:0006397	mRNA processing
0.52	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.51	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.49	GO:0051663	oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
0.49	GO:0000335	negative regulation of transposition, DNA-mediated
0.48	GO:0007317	regulation of pole plasm oskar mRNA localization
0.48	GO:0007294	germarium-derived oocyte fate determination
0.47	GO:0007314	oocyte anterior/posterior axis specification

0.75	GO:0003729	mRNA binding
0.35	GO:0008488	gamma-glutamyl carboxylase activity
0.35	GO:0005515	protein binding
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0016607	nuclear speck
0.57	GO:0035145	exon-exon junction complex
0.49	GO:0005737	cytoplasm
0.49	GO:0071013	catalytic step 2 spliceosome
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.34	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.35

EC:4.1.1

GO:0008488

sp|Q9V557|CP4P2_DROME
Probable cytochrome P450 4p2
Search

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0007596	blood coagulation
0.33	GO:0006508	proteolysis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0004252	serine-type endopeptidase activity

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V558|CP4P1_DROME
Cytochrome P450 4p1
Search

0.11	Putative cytochrome

0.53	GO:0055114	oxidation-reduction process
0.38	GO:0030258	lipid modification
0.38	GO:0006631	fatty acid metabolic process
0.34	GO:0001523	retinoid metabolic process
0.33	GO:0007601	visual perception
0.33	GO:0016125	sterol metabolic process
0.33	GO:0055085	transmembrane transport
0.32	GO:0050896	response to stimulus

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.34	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.68

GO:0016705

sp|Q9V559|CP4P3_DROME
Probable cytochrome P450 4p3
Search

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0055085	transmembrane transport
0.33	GO:0030258	lipid modification
0.33	GO:0006631	fatty acid metabolic process
0.32	GO:0007165	signal transduction

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.35	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.68

GO:0016705

sp|Q9V564|COG6_DROME
Conserved oligomeric Golgi complex subunit 6
Search

0.71	Oligomeric Golgi complex subunit

0.82	GO:0006891	intra-Golgi vesicle-mediated transport
0.36	GO:0070085	glycosylation
0.34	GO:0015031	protein transport
0.33	GO:0006508	proteolysis
0.33	GO:0065007	biological regulation
0.33	GO:0006468	protein phosphorylation
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.32	GO:0051716	cellular response to stimulus

0.34	GO:0017049	GTP-Rho binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0003723	RNA binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0016301	kinase activity
0.32	GO:0003677	DNA binding

0.81	GO:0017119	Golgi transport complex
0.35	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016773

sp|Q9V568|OR45A_DROME
Odorant receptor 45a
Search

0.50	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.56	GO:0005886	plasma membrane
0.46	GO:0030425	dendrite
0.46	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V574|L2K1_DROME
Protein lethal(2)k10201
Search

0.61

GO:0007275

multicellular organism development

0.51	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding

sp|Q9V576|WUN_DROME
Putative phosphatidate phosphatase
Search

0.79	Lipid phosphate phosphohydrolase

0.57	GO:0035233	germ cell repulsion
0.56	GO:0016311	dephosphorylation
0.51	GO:0019991	septate junction assembly
0.50	GO:0007424	open tracheal system development
0.48	GO:0006629	lipid metabolic process
0.45	GO:0007280	pole cell migration
0.43	GO:0007277	pole cell development
0.42	GO:0035234	ectopic germ cell programmed cell death
0.41	GO:0007281	germ cell development
0.39	GO:0006869	lipid transport

0.62	GO:0008195	phosphatidate phosphatase activity
0.52	GO:0042577	lipid phosphatase activity
0.40	GO:0005319	lipid transporter activity
0.36	GO:0042803	protein homodimerization activity
0.34	GO:0042392	sphingosine-1-phosphate phosphatase activity

0.51	GO:0005918	septate junction
0.51	GO:0045177	apical part of cell
0.45	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.62

EC:3.1.3.4

GO:0008195

sp|Q9V579|PREL_DROME
Protein preli-like
Search

0.80	PRELI domain-containing protein 1, mitochondrial

0.55	GO:0070584	mitochondrion morphogenesis
0.54	GO:0048813	dendrite morphogenesis
0.39	GO:0015914	phospholipid transport

0.41

GO:1990050

phosphatidic acid transporter activity

0.79	GO:0005758	mitochondrial intermembrane space
0.55	GO:0030061	mitochondrial crista

sp|Q9V589|OR45B_DROME
Odorant receptor 45b
Search

0.47	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.55	GO:0005886	plasma membrane
0.45	GO:0030425	dendrite
0.44	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V595|DCUP_DROME
Uroporphyrinogen decarboxylase
Search

0.49	Uroporphyrinogen decarboxylase

0.72	GO:0006782	protoporphyrinogen IX biosynthetic process
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.79	GO:0004853	uroporphyrinogen decarboxylase activity
0.34	GO:0003735	structural constituent of ribosome

0.36	GO:0005829	cytosol
0.34	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:4.1.1.37

GO:0004853

sp|Q9V597|RL31_DROME
60S ribosomal protein L31
Search

0.57	Large subunit ribosomal protein L31e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0006782	protoporphyrinogen IX biosynthetic process
0.34	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0004853	uroporphyrinogen decarboxylase activity
0.34	GO:0004416	hydroxyacylglutathione hydrolase activity

0.61	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005844	polysome
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:4.1.1.37

GO:0004853

sp|Q9V5C6|PSA3_DROME
Proteasome subunit alpha type-3
Search

0.48	Proteasome endopeptidase complex

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.43	GO:0030707	ovarian follicle cell development
0.42	GO:0010498	proteasomal protein catabolic process
0.39	GO:0052548	regulation of endopeptidase activity
0.36	GO:0008063	Toll signaling pathway
0.35	GO:0007623	circadian rhythm
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway

0.77	GO:0004298	threonine-type endopeptidase activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0005515	protein binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.35	GO:0045202	synapse
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0070062	extracellular exosome
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.77

EC:3.4.25

GO:0004298

sp|Q9V5E1|PAL1_DROME
Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 1
Search

0.74	Peptidyl-glycine alpha-amidating monooxygenase

0.59	GO:0006518	peptide metabolic process
0.52	GO:0044719	regulation of imaginal disc-derived wing size
0.45	GO:0055114	oxidation-reduction process
0.38	GO:0007619	courtship behavior
0.33	GO:0010951	negative regulation of endopeptidase activity
0.33	GO:0035556	intracellular signal transduction

0.63	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.56	GO:0004598	peptidylamidoglycolate lyase activity
0.50	GO:0005507	copper ion binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0046983	protein dimerization activity
0.32	GO:0003676	nucleic acid binding

0.49	GO:0043025	neuronal cell body
0.34	GO:0005886	plasma membrane
0.32	GO:0005576	extracellular region
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.63

EC:1.14.17

GO:0016715

sp|Q9V5L3|C49A1_DROME
Probable cytochrome P450 49a1
Search

0.53

GO:0055114

oxidation-reduction process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.63	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0003723	RNA binding

0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V5N8|STAN_DROME
Protocadherin-like wing polarity protein stan
Search

STAN

0.56	Neural-cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0048057	R3/R4 development
0.57	GO:0070593	dendrite self-avoidance
0.57	GO:0016318	ommatidial rotation
0.57	GO:1902669	positive regulation of axon guidance
0.57	GO:0035159	regulation of tube length, open tracheal system
0.57	GO:0007367	segment polarity determination
0.56	GO:0016319	mushroom body development

0.71	GO:0004930	G-protein coupled receptor activity
0.70	GO:0005509	calcium ion binding
0.52	GO:0005057	signal transducer activity, downstream of receptor
0.38	GO:0050839	cell adhesion molecule binding

0.55	GO:0005886	plasma membrane
0.51	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|Q9V5P6|NOP10_DROME
H/ACA ribonucleoprotein complex subunit 3
Search

0.52	H/ACA ribonucleoprotein complex subunit

0.72	GO:0001522	pseudouridine synthesis
0.67	GO:0042254	ribosome biogenesis
0.51	GO:0040031	snRNA modification
0.47	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.46	GO:0007004	telomere maintenance via telomerase
0.45	GO:0016072	rRNA metabolic process
0.44	GO:0034470	ncRNA processing
0.42	GO:0010197	polar nucleus fusion
0.40	GO:0090501	RNA phosphodiester bond hydrolysis
0.39	GO:0060215	primitive hemopoiesis

0.83	GO:0030515	snoRNA binding
0.46	GO:0070034	telomerase RNA binding
0.35	GO:0000250	lanosterol synthase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0004822	isoleucine-tRNA ligase activity
0.33	GO:0005506	iron ion binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0002161	aminoacyl-tRNA editing activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0030554	adenyl nucleotide binding

0.52	GO:0019013	viral nucleocapsid
0.50	GO:0030529	intracellular ribonucleoprotein complex
0.49	GO:0015030	Cajal body
0.48	GO:0005730	nucleolus
0.41	GO:1902494	catalytic complex
0.33	GO:0005811	lipid droplet
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:5.4.99.7	GO:0000250
0.35	KEGG:R03199	GO:0000250

sp|Q9V5Q4|SYF2_DROME
Pre-mRNA-splicing factor Syf2
Search

SYF2

0.75	Pre-mRNA-splicing factor Syf2

0.63	GO:0007095	mitotic G2 DNA damage checkpoint
0.60	GO:0007369	gastrulation
0.59	GO:0001701	in utero embryonic development
0.59	GO:0048568	embryonic organ development
0.52	GO:0008380	RNA splicing
0.50	GO:0006397	mRNA processing
0.43	GO:0008284	positive regulation of cell proliferation
0.39	GO:0032781	positive regulation of ATPase activity
0.38	GO:0072488	ammonium transmembrane transport
0.37	GO:0008610	lipid biosynthetic process

0.39	GO:0001671	ATPase activator activity
0.39	GO:0003723	RNA binding
0.38	GO:0051087	chaperone binding
0.38	GO:0008519	ammonium transmembrane transporter activity
0.37	GO:0005506	iron ion binding
0.37	GO:0016853	isomerase activity
0.35	GO:0016491	oxidoreductase activity
0.33	GO:0140096	catalytic activity, acting on a protein

0.77	GO:0071013	catalytic step 2 spliceosome
0.71	GO:0000974	Prp19 complex
0.71	GO:0071014	post-mRNA release spliceosomal complex
0.65	GO:0005684	U2-type spliceosomal complex
0.63	GO:0016607	nuclear speck
0.42	GO:0071012	catalytic step 1 spliceosome
0.42	GO:0071011	precatalytic spliceosome
0.41	GO:0071010	prespliceosome
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016853

sp|Q9V5Z7|AQP_DROME
Aquaporin
Search

0.49	Aquaporin-1 transcript variant B

0.55	GO:0055085	transmembrane transport
0.46	GO:0006833	water transport
0.42	GO:0019755	one-carbon compound transport
0.40	GO:0048235	pollen sperm cell differentiation
0.39	GO:0030157	pancreatic juice secretion
0.39	GO:0046541	saliva secretion
0.38	GO:0042476	odontogenesis
0.38	GO:0048593	camera-type eye morphogenesis
0.37	GO:0015669	gas transport
0.36	GO:0006811	ion transport

0.69	GO:0022803	passive transmembrane transporter activity
0.46	GO:0005372	water transmembrane transporter activity
0.39	GO:0015204	urea transmembrane transporter activity
0.36	GO:0042802	identical protein binding
0.33	GO:0015168	glycerol transmembrane transporter activity
0.32	GO:0003676	nucleic acid binding

0.40	GO:0120025	plasma membrane bounded cell projection
0.38	GO:0009925	basal plasma membrane
0.38	GO:0042807	central vacuole
0.38	GO:0005887	integral component of plasma membrane
0.38	GO:0016324	apical plasma membrane
0.37	GO:0009705	plant-type vacuole membrane
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005739	mitochondrion
0.33	GO:0070062	extracellular exosome
0.33	GO:0016328	lateral plasma membrane

sp|Q9V629|CUFF_DROME
Protein cutoff
Search

0.87	GO:0030723	ovarian fusome organization
0.87	GO:0030719	P granule organization
0.87	GO:0030727	germarium-derived female germ-line cyst formation
0.86	GO:0030717	karyosome formation
0.86	GO:0034587	piRNA metabolic process
0.85	GO:0030422	production of siRNA involved in RNA interference
0.83	GO:0009953	dorsal/ventral pattern formation

0.45

GO:0005515

protein binding

0.79	GO:0048471	perinuclear region of cytoplasm
0.61	GO:0005634	nucleus
0.47	GO:0005694	chromosome

sp|Q9V637|PSMF1_DROME
Proteasome inhibitor PI31 subunit
Search

0.77	Proteasome inhibitor

0.69	GO:0007140	male meiotic nuclear division
0.69	GO:0008584	male gonad development
0.69	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.66	GO:0043248	proteasome assembly
0.36	GO:0006511	ubiquitin-dependent protein catabolic process

0.39

GO:0005515

protein binding

0.75	GO:0070864	sperm individualization complex
0.62	GO:1905369	endopeptidase complex
0.52	GO:0043234	protein complex
0.41	GO:0044424	intracellular part

sp|Q9V668|S61G1_DROME
Protein transport protein Sec61 gamma-1 subunit
Search

SEC61G

0.91	Preprotein translocase gamma subunit

0.71	GO:0006605	protein targeting
0.70	GO:0071806	protein transmembrane transport
0.41	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.37	GO:0010507	negative regulation of autophagy
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.35	GO:0001555	oocyte growth
0.35	GO:0030728	ovulation
0.34	GO:0022406	membrane docking

0.75	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.34	GO:0005543	phospholipid binding
0.33	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0044422	organelle part
0.37	GO:0043227	membrane-bounded organelle
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V674|CP6G1_DROME
Cytochrome P450 6g1
Search

0.45	Cytochrome P450 monooxygenase 6g2

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0046680	response to DDT
0.51	GO:0046701	insecticide catabolic process
0.47	GO:0046683	response to organophosphorus
0.46	GO:0046689	response to mercury ion
0.39	GO:0007608	sensory perception of smell
0.39	GO:0009822	alkaloid catabolic process
0.38	GO:0002933	lipid hydroxylation
0.37	GO:0008202	steroid metabolic process
0.37	GO:0070988	demethylation

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0030343	vitamin D3 25-hydroxylase activity
0.35	GO:0034875	caffeine oxidase activity
0.34	GO:0070576	vitamin D 24-hydroxylase activity
0.34	GO:0032947	protein complex scaffold activity
0.34	GO:0005496	steroid binding
0.33	GO:0019899	enzyme binding

0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V675|CP6G2_DROME
Probable cytochrome P450 6g2
Search

0.40	Cytochrome P450 monooxygenase 6g2

0.57	GO:0017085	response to insecticide
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0046683	response to organophosphorus
0.41	GO:0046689	response to mercury ion
0.41	GO:0042178	xenobiotic catabolic process
0.41	GO:0014070	response to organic cyclic compound
0.40	GO:0009407	toxin catabolic process
0.39	GO:0042493	response to drug
0.36	GO:0007608	sensory perception of smell
0.36	GO:0043248	proteasome assembly

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.36	GO:0032947	protein complex scaffold activity
0.34	GO:0031418	L-ascorbic acid binding
0.33	GO:0003958	NADPH-hemoprotein reductase activity

0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q9V676|CP6T3_DROME
Probable cytochrome P450 6t3
Search

0.53	GO:0006697	ecdysone biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0048638	regulation of developmental growth
0.33	GO:0021661	rhombomere 4 morphogenesis
0.33	GO:0055014	atrial cardiac muscle cell development
0.33	GO:0033339	pectoral fin development
0.33	GO:0042573	retinoic acid metabolic process
0.33	GO:0003151	outflow tract morphogenesis
0.33	GO:0070988	demethylation
0.33	GO:0001944	vasculature development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0032451	demethylase activity
0.32	GO:0008168	methyltransferase activity
0.31	GO:0016787	hydrolase activity

0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.35	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V677|ECM29_DROME
Proteasome-associated protein ECM29 homolog
Search

0.70	Proteasome stabiliser

0.81	GO:0043248	proteasome assembly
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0016255	attachment of GPI anchor to protein

0.81	GO:0032947	protein complex scaffold activity
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.36	GO:0004497	monooxygenase activity
0.35	GO:0020037	heme binding
0.35	GO:0005506	iron ion binding

0.55	GO:1905369	endopeptidase complex
0.47	GO:0043234	protein complex
0.39	GO:0044424	intracellular part
0.35	GO:0043227	membrane-bounded organelle
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.36

GO:0016705

sp|Q9V6A9|OR49A_DROME
Odorant receptor 49a
Search

0.49	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.73	GO:0042048	olfactory behavior
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.56	GO:0005886	plasma membrane
0.47	GO:0030425	dendrite
0.47	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V6B9|NUP54_DROME
Probable nucleoporin Nup54
Search

NUP54

0.85	Nuclear pore complex protein Nup54

0.54	GO:0006607	NLS-bearing protein import into nucleus
0.46	GO:0036228	protein localization to nuclear inner membrane
0.45	GO:0006999	nuclear pore organization
0.38	GO:0051028	mRNA transport
0.37	GO:0006605	protein targeting
0.35	GO:0007077	mitotic nuclear envelope disassembly
0.35	GO:0070208	protein heterotrimerization
0.35	GO:1900034	regulation of cellular response to heat
0.35	GO:0051290	protein heterotetramerization
0.35	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus

0.53	GO:0005487	structural constituent of nuclear pore
0.35	GO:0005515	protein binding
0.33	GO:0008139	nuclear localization sequence binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0004872	receptor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding

0.77	GO:0005643	nuclear pore
0.34	GO:0031965	nuclear membrane
0.33	GO:0005764	lysosome
0.33	GO:0044215	other organism
0.30	GO:0016021	integral component of membrane

sp|Q9V6D6|CP301_DROME
Probable cytochrome P450 301a1, mitochondrial
Search

0.37	Cytochrome P450 monooxygenase

0.53	GO:0007490	tergite morphogenesis
0.53	GO:0055114	oxidation-reduction process
0.32	GO:0006281	DNA repair

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.52	GO:0004497	monooxygenase activity

0.34	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V6G5|TAZ_DROME
Tafazzin homolog
Search

0.71	Tafazzin homolog

0.67	GO:0006644	phospholipid metabolic process
0.51	GO:0007291	sperm individualization
0.49	GO:0007006	mitochondrial membrane organization
0.46	GO:0046486	glycerolipid metabolic process
0.43	GO:0008610	lipid biosynthetic process
0.41	GO:0090407	organophosphate biosynthetic process
0.40	GO:0016579	protein deubiquitination
0.39	GO:0006511	ubiquitin-dependent protein catabolic process
0.37	GO:0044249	cellular biosynthetic process
0.36	GO:0045823	positive regulation of heart contraction

0.63	GO:0016746	transferase activity, transferring acyl groups
0.40	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.42	GO:0005739	mitochondrion
0.36	GO:0031967	organelle envelope
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.63

EC:2.3

GO:0016746

sp|Q9V6H1|CP9H1_DROME
Probable cytochrome P450 9h1
Search

0.45	Putative cytochrome

0.53

GO:0055114

oxidation-reduction process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0003958	NADPH-hemoprotein reductase activity

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V6H2|OR49B_DROME
Odorant receptor 49b
Search

0.52	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction
0.36	GO:0006013	mannose metabolic process

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity
0.35	GO:0004559	alpha-mannosidase activity
0.35	GO:0030246	carbohydrate binding

0.52	GO:0005886	plasma membrane
0.40	GO:0030425	dendrite
0.40	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.2.1.24

GO:0004559

sp|Q9V6K1|TPP2_DROME
Tripeptidyl-peptidase 2
Search

0.68	Tripeptidyl-peptidase

0.60	GO:0006508	proteolysis
0.50	GO:0051260	protein homooligomerization
0.32	GO:0055114	oxidation-reduction process

0.75	GO:0008240	tripeptidyl-peptidase activity
0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0042802	identical protein binding
0.36	GO:0004177	aminopeptidase activity
0.32	GO:0016491	oxidoreductase activity

0.34	GO:0005739	mitochondrion
0.34	GO:0022626	cytosolic ribosome
0.34	GO:0005774	vacuolar membrane
0.33	GO:0009507	chloroplast
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.4.14

GO:0008240

sp|Q9V6K3|ROR2_DROME
Tyrosine-protein kinase transmembrane receptor Ror2
Search

0.67	Tyrosine-protein kinase transmembrane receptor Ror2

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.52	GO:0072499	photoreceptor cell axon guidance
0.52	GO:0042052	rhabdomere development
0.51	GO:0046716	muscle cell cellular homeostasis
0.49	GO:0007528	neuromuscular junction development
0.44	GO:0001934	positive regulation of protein phosphorylation
0.42	GO:0001941	postsynaptic membrane organization
0.42	GO:0043113	receptor clustering
0.41	GO:0007165	signal transduction
0.41	GO:0048638	regulation of developmental growth

0.77	GO:0004713	protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0019199	transmembrane receptor protein kinase activity
0.39	GO:0005515	protein binding
0.39	GO:0003777	microtubule motor activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0046872	metal ion binding

0.44	GO:0043235	receptor complex
0.41	GO:0045211	postsynaptic membrane
0.36	GO:0031594	neuromuscular junction
0.35	GO:0030054	cell junction
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0009897	external side of plasma membrane
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0042995	cell projection

0.77

EC:2.7.10

GO:0004713

sp|Q9V6L0|KDM4B_DROME
Probable lysine-specific demethylase 4B
Search

0.85	JmjC domain-containing histone demethylation protein 3C

0.47	GO:0070544	histone H3-K36 demethylation
0.45	GO:0033169	histone H3-K9 demethylation
0.45	GO:0032259	methylation
0.38	GO:0010628	positive regulation of gene expression
0.35	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0055114	oxidation-reduction process
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.34	GO:0006351	transcription, DNA-templated

0.48	GO:0051864	histone demethylase activity (H3-K36 specific)
0.45	GO:0032454	histone demethylase activity (H3-K9 specific)
0.45	GO:0008168	methyltransferase activity
0.40	GO:0046872	metal ion binding
0.39	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.40	GO:0000792	heterochromatin
0.30	GO:0016020	membrane

0.48

EC:1.14.11.27

GO:0051864

sp|Q9V6L9|FBSP1_DROME
F-box/SPRY domain-containing protein 1
Search

FSN

0.91	F-box/SPRY domain-containing protein 1

0.83	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.80	GO:0007274	neuromuscular synaptic transmission
0.73	GO:0016567	protein ubiquitination
0.73	GO:0007399	nervous system development
0.70	GO:0045732	positive regulation of protein catabolic process
0.60	GO:0010629	negative regulation of gene expression
0.52	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.50	GO:0050808	synapse organization
0.49	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.49	GO:0060322	head development

0.42	GO:0005515	protein binding
0.41	GO:0004842	ubiquitin-protein transferase activity

0.79	GO:0031594	neuromuscular junction
0.76	GO:0045495	pole plasm
0.75	GO:0019005	SCF ubiquitin ligase complex
0.72	GO:0030054	cell junction
0.67	GO:0005938	cell cortex
0.55	GO:0005634	nucleus
0.51	GO:0014069	postsynaptic density
0.49	GO:0042734	presynaptic membrane
0.47	GO:0045211	postsynaptic membrane
0.44	GO:0043204	perikaryon

0.41

GO:0004842

sp|Q9V6Q2|CID_DROME
Histone H3-like centromeric protein cid
Search

CID

0.97	Centromeric histone Cid

0.55	GO:0031937	positive regulation of chromatin silencing
0.53	GO:0007080	mitotic metaphase plate congression
0.53	GO:0051382	kinetochore assembly
0.52	GO:0051225	spindle assembly
0.41	GO:0061641	CENP-A containing chromatin organization
0.37	GO:0006334	nucleosome assembly
0.32	GO:0051205	protein insertion into membrane
0.32	GO:0006468	protein phosphorylation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.49	GO:0003777	microtubule motor activity
0.37	GO:0031491	nucleosome binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.57	GO:0061638	CENP-A containing chromatin
0.54	GO:0000939	condensed chromosome inner kinetochore
0.47	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V6U8|UBA3_DROME
Nedd8-activating enzyme E1 catalytic subunit
Search

UBA3

0.76	Ubiquitin like modifier activating enzyme 3

0.84	GO:0045116	protein neddylation
0.48	GO:0045879	negative regulation of smoothened signaling pathway
0.35	GO:0007113	endomitotic cell cycle
0.34	GO:0006465	signal peptide processing
0.33	GO:0051726	regulation of cell cycle
0.33	GO:0006629	lipid metabolic process

0.84	GO:0019781	NEDD8 activating enzyme activity
0.71	GO:0016881	acid-amino acid ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0052689	carboxylic ester hydrolase activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0042802	identical protein binding
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.39	GO:0043234	protein complex
0.39	GO:0005576	extracellular region
0.35	GO:0005737	cytoplasm
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.71	EC:6.3.2	GO:0016881
0.38	KEGG:R00630	GO:0052689

sp|Q9V6U9|MECR_DROME
Enoyl-[acyl-carrier-protein] reductase, mitochondrial
Search

0.37	Zinc binding dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.35	GO:0006633	fatty acid biosynthetic process
0.33	GO:0032392	DNA geometric change

0.53	GO:0016491	oxidoreductase activity
0.36	GO:0008270	zinc ion binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0003678	DNA helicase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.34	GO:0005739	mitochondrion
0.32	GO:0005634	nucleus

0.53

GO:0016491

sp|Q9V6X7|OFUT1_DROME
GDP-fucose protein O-fucosyltransferase 1
Search

0.75	GDP-fucose protein O-fucosyltransferase

0.79	GO:0006004	fucose metabolic process
0.59	GO:0036066	protein O-linked fucosylation
0.55	GO:0008593	regulation of Notch signaling pathway
0.48	GO:0001756	somitogenesis
0.48	GO:0007219	Notch signaling pathway
0.47	GO:0001525	angiogenesis
0.46	GO:0007507	heart development
0.46	GO:0098609	cell-cell adhesion
0.45	GO:0009967	positive regulation of signal transduction
0.45	GO:0007399	nervous system development

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.49	GO:0005112	Notch binding
0.44	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0019211	phosphatase activator activity
0.34	GO:0000150	recombinase activity
0.34	GO:0003697	single-stranded DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.33	GO:0008094	DNA-dependent ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.49	GO:0005783	endoplasmic reticulum
0.44	GO:0031410	cytoplasmic vesicle
0.37	GO:0005794	Golgi apparatus
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005634	nucleus
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.65

GO:0016757

sp|Q9V6Y3|RT16_DROME
Probable 28S ribosomal protein S16, mitochondrial
Search

0.93	28S ribosomal protein S16, mitochondrial

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.33	GO:0035176	social behavior
0.33	GO:0032781	positive regulation of ATPase activity
0.33	GO:0043624	cellular protein complex disassembly
0.33	GO:0016311	dephosphorylation
0.32	GO:0036211	protein modification process

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
0.33	GO:0031072	heat shock protein binding
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.61	GO:0005840	ribosome
0.45	GO:0005759	mitochondrial matrix
0.39	GO:0005829	cytosol
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.33	GO:0005615	extracellular space
0.33	GO:0005654	nucleoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.2.1.96

GO:0033925

sp|Q9V719|SIN1_DROME
Stress-activated map kinase-interacting protein 1
Search

SIN1

0.76	Stress-activated map kinase-interacting protein 1

0.67	GO:0051124	synaptic growth at neuromuscular junction
0.66	GO:0034063	stress granule assembly
0.64	GO:0048813	dendrite morphogenesis
0.57	GO:0001932	regulation of protein phosphorylation
0.44	GO:0038203	TORC2 signaling
0.44	GO:0030950	establishment or maintenance of actin cytoskeleton polarity
0.43	GO:0006915	apoptotic process
0.43	GO:0031098	stress-activated protein kinase signaling cascade
0.41	GO:0016310	phosphorylation
0.34	GO:0090133	mesendoderm migration

0.43	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.42	GO:0016301	kinase activity
0.40	GO:0019901	protein kinase binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.82	GO:0031932	TORC2 complex
0.36	GO:0005886	plasma membrane
0.35	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34

GO:0004553

sp|Q9V726|CPSF1_DROME
Cleavage and polyadenylation specificity factor subunit 1
Search

CPSF1

0.88	Cleavage and polyadenylation specificity factor cpsf

0.51	GO:0006378	mRNA polyadenylation
0.44	GO:0006379	mRNA cleavage
0.43	GO:0060216	definitive hemopoiesis
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0051028	mRNA transport
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006405	RNA export from nucleus

0.54	GO:0017022	myosin binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0019899	enzyme binding
0.37	GO:0005509	calcium ion binding

0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043234	protein complex
0.40	GO:0044446	intracellular organelle part

sp|Q9V727|ASX_DROME
Polycomb protein Asx
Search

0.87	Polycomb protein Asx

0.74	GO:2000158	positive regulation of ubiquitin-specific protease activity
0.73	GO:0035186	syncytial blastoderm mitotic cell cycle
0.72	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.72	GO:0007469	antennal development
0.71	GO:0035522	monoubiquitinated histone H2A deubiquitination
0.68	GO:0001709	cell fate determination
0.48	GO:0010468	regulation of gene expression
0.47	GO:0045498	sex comb development
0.41	GO:1903508	positive regulation of nucleic acid-templated transcription
0.41	GO:1903507	negative regulation of nucleic acid-templated transcription

0.74	GO:0035800	deubiquitinase activator activity
0.63	GO:0003682	chromatin binding
0.53	GO:0003677	DNA binding
0.39	GO:0005515	protein binding
0.36	GO:0046872	metal ion binding
0.32	GO:0004842	ubiquitin-protein transferase activity

0.74	GO:0035517	PR-DUB complex
0.59	GO:0000785	chromatin
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.32

GO:0004842

sp|Q9V730|EXT1_DROME
Exostosin-1
Search

0.85	Exostosin like glycosyltransferase 1

0.73	GO:0009101	glycoprotein biosynthetic process
0.73	GO:0043413	macromolecule glycosylation
0.59	GO:0036211	protein modification process
0.57	GO:0030201	heparan sulfate proteoglycan metabolic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0090098	positive regulation of decapentaplegic signaling pathway
0.53	GO:0030210	heparin biosynthetic process
0.51	GO:0008354	germ cell migration
0.51	GO:0045880	positive regulation of smoothened signaling pathway
0.51	GO:0048312	intracellular distribution of mitochondria

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.35	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.49	GO:0005783	endoplasmic reticulum
0.47	GO:0045202	synapse
0.46	GO:0005794	Golgi apparatus
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.65

GO:0016757

sp|Q9V751|ATTB_DROME
Attacin-B
Search

0.95	Antimicrobial peptide Attacin B

0.78	GO:0042742	defense response to bacterium
0.40	GO:0019730	antimicrobial humoral response
0.39	GO:0045087	innate immune response

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q9V769|C6A22_DROME
Cytochrome P450 6a22
Search

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0017085	response to insecticide
0.45	GO:0031000	response to caffeine
0.39	GO:0048252	lauric acid metabolic process
0.36	GO:0006805	xenobiotic metabolic process
0.36	GO:0009404	toxin metabolic process
0.35	GO:0002118	aggressive behavior
0.34	GO:0050829	defense response to Gram-negative bacterium
0.33	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0009055	electron transfer activity
0.32	GO:0016787	hydrolase activity

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q9V770|C6A17_DROME
Probable cytochrome P450 6a17
Search

0.48	p450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.42	GO:0040040	thermosensory behavior
0.35	GO:0048252	lauric acid metabolic process
0.35	GO:0017143	insecticide metabolic process
0.35	GO:0002118	aggressive behavior
0.35	GO:0031000	response to caffeine
0.34	GO:0050829	defense response to Gram-negative bacterium
0.32	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0009055	electron transfer activity
0.32	GO:0016787	hydrolase activity

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q9V771|C6A23_DROME
Probable cytochrome P450 6a23
Search

0.48	p450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.41	GO:0040040	thermosensory behavior
0.35	GO:0002118	aggressive behavior
0.34	GO:0050829	defense response to Gram-negative bacterium
0.32	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0009055	electron transfer activity

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V773|C6A20_DROME
Probable cytochrome P450 6a20
Search

0.48	p450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.41	GO:0048252	lauric acid metabolic process
0.40	GO:0017143	insecticide metabolic process
0.39	GO:0031000	response to caffeine
0.39	GO:0040040	thermosensory behavior
0.36	GO:0002118	aggressive behavior
0.36	GO:0050829	defense response to Gram-negative bacterium
0.33	GO:0006091	generation of precursor metabolites and energy
0.33	GO:0045892	negative regulation of transcription, DNA-templated

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0003714	transcription corepressor activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0003700	DNA binding transcription factor activity

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q9V774|C6A21_DROME
Probable cytochrome P450 6a21
Search

0.37	Cytochrome P450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0017085	response to insecticide
0.47	GO:0031000	response to caffeine
0.41	GO:0048252	lauric acid metabolic process
0.38	GO:0006805	xenobiotic metabolic process
0.37	GO:0009404	toxin metabolic process
0.34	GO:0002118	aggressive behavior
0.34	GO:0050829	defense response to Gram-negative bacterium
0.34	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0009055	electron transfer activity
0.32	GO:0016787	hydrolase activity

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|Q9V776|CP317_DROME
Probable cytochrome P450 317a1
Search

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0042742	defense response to bacterium
0.32	GO:0044550	secondary metabolite biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0016829	lyase activity
0.31	GO:0016787	hydrolase activity

0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V778|ADAS_DROME
Alkyldihydroxyacetonephosphate synthase
Search

0.76	Alkyldihydroxyacetonephosphate synthase

0.85	GO:0008611	ether lipid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0005975	carbohydrate metabolic process
0.32	GO:0006811	ion transport
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.86	GO:0008609	alkylglycerone-phosphate synthase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.34	GO:0008061	chitin binding
0.33	GO:0046872	metal ion binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0003735	structural constituent of ribosome

0.76	GO:0005777	peroxisome
0.40	GO:0005730	nucleolus
0.34	GO:0005921	gap junction
0.34	GO:0031903	microbody membrane
0.33	GO:0005739	mitochondrion
0.33	GO:0005840	ribosome
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.5.1.26

GO:0008609

sp|Q9V780|LAP1_DROME
Protein lap1
Search

0.72	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.60	GO:0007165	signal transduction
0.58	GO:0010976	positive regulation of neuron projection development
0.52	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
0.51	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.51	GO:0032495	response to muramyl dipeptide
0.50	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.49	GO:0071356	cellular response to tumor necrosis factor
0.48	GO:0032496	response to lipopolysaccharide
0.47	GO:0015031	protein transport

0.76	GO:0005176	ErbB-2 class receptor binding
0.42	GO:0005178	integrin binding
0.39	GO:0008022	protein C-terminus binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016740	transferase activity

0.56	GO:0098590	plasma membrane region
0.55	GO:0030054	cell junction
0.55	GO:0043005	neuron projection
0.47	GO:0016607	nuclear speck
0.45	GO:0014069	postsynaptic density
0.43	GO:0005737	cytoplasm
0.40	GO:0012505	endomembrane system
0.40	GO:0031983	vesicle lumen
0.39	GO:0030175	filopodium
0.38	GO:0036477	somatodendritic compartment

0.32

GO:0016740

sp|Q9V784|SAM50_DROME
SAM50-like protein CG7639
Search

0.38	Surface antigen

0.34	GO:0003924	GTPase activity
0.34	GO:0001883	purine nucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0032549	ribonucleoside binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0019867	outer membrane
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0031966	mitochondrial membrane
0.30	GO:0044425	membrane part

sp|Q9V785|3BP5H_DROME
SH3 domain-binding protein 5 homolog
Search

0.77	SH3 domain-binding protein 5 homolog

0.63	GO:0035556	intracellular signal transduction
0.54	GO:0061099	negative regulation of protein tyrosine kinase activity
0.51	GO:0007301	female germline ring canal formation
0.51	GO:0042694	muscle cell fate specification
0.48	GO:0048644	muscle organ morphogenesis
0.48	GO:0007498	mesoderm development
0.47	GO:0009952	anterior/posterior pattern specification
0.33	GO:0006629	lipid metabolic process

0.44	GO:0004860	protein kinase inhibitor activity
0.44	GO:0017124	SH3 domain binding
0.34	GO:0042302	structural constituent of cuticle

0.45	GO:0005622	intracellular
0.39	GO:0005886	plasma membrane

sp|Q9V7A4|ITA4_DROME
Integrin alpha-PS4
Search

0.82	Putative vitronectin receptor alpha subunit

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.64	GO:0001555	oocyte growth
0.54	GO:0007508	larval heart development
0.53	GO:0035001	dorsal trunk growth, open tracheal system
0.53	GO:0003344	pericardium morphogenesis
0.52	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.51	GO:0048149	behavioral response to ethanol
0.51	GO:0007391	dorsal closure
0.51	GO:0043277	apoptotic cell clearance

0.49	GO:0046982	protein heterodimerization activity
0.42	GO:0050839	cell adhesion molecule binding
0.38	GO:0004872	receptor activity
0.34	GO:0070006	metalloaminopeptidase activity
0.33	GO:0050840	extracellular matrix binding
0.32	GO:0042802	identical protein binding
0.32	GO:0032403	protein complex binding
0.32	GO:0005102	receptor binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0046872	metal ion binding

0.81	GO:0008305	integrin complex
0.51	GO:0009925	basal plasma membrane
0.49	GO:0016324	apical plasma membrane
0.37	GO:0005737	cytoplasm
0.37	GO:0005925	focal adhesion
0.37	GO:0016328	lateral plasma membrane
0.34	GO:0009897	external side of plasma membrane
0.33	GO:0031982	vesicle
0.33	GO:0032587	ruffle membrane
0.33	GO:0043230	extracellular organelle

sp|Q9V7A7|GPAN1_DROME
G patch domain and ankyrin repeat-containing protein 1 homolog
Search

0.78	G patch domain and ankyrin repeat-containing protein 1

0.51	GO:0003676	nucleic acid binding
0.37	GO:0008270	zinc ion binding
0.33	GO:0043531	ADP binding

sp|Q9V7D2|VATD1_DROME
V-type proton ATPase subunit D 1
Search

0.64	Vacuolar ATP synthase subunit D

0.55	GO:0055085	transmembrane transport
0.38	GO:0061512	protein localization to cilium
0.37	GO:0060271	cilium assembly
0.35	GO:0015992	proton transport
0.35	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.34	GO:0006281	DNA repair
0.34	GO:0055114	oxidation-reduction process

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0022853	active ion transmembrane transporter activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016491	oxidoreductase activity
0.33	GO:0005515	protein binding

0.46	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.37	GO:0005813	centrosome
0.37	GO:0005929	cilium
0.35	GO:0005774	vacuolar membrane
0.34	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.34	GO:0005764	lysosome
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.34

GO:0016491

sp|Q9V7G5|C4AA1_DROME
Probable cytochrome P450 4aa1
Search

0.11	Putative cytochrome

0.53	GO:0055114	oxidation-reduction process
0.32	GO:0006629	lipid metabolic process
0.32	GO:0006508	proteolysis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0004252	serine-type endopeptidase activity

0.36	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q9V7H4|TM131_DROME
Transmembrane protein 131 homolog
Search

0.30

GO:0008152

metabolic process

0.42	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
0.37	GO:0048037	cofactor binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.42

EC:2.3.3

GO:0046912

sp|Q9V7N5|VATC_DROME
V-type proton ATPase subunit C
Search

0.42	V-type proton ATPase subunit C

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.34	GO:0090383	phagosome acidification
0.34	GO:0033572	transferrin transport
0.34	GO:0008286	insulin receptor signaling pathway
0.34	GO:0016241	regulation of macroautophagy
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.46	GO:0036442	proton-exporting ATPase activity
0.45	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.39	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.50	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.42	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.42	GO:0005765	lysosomal membrane
0.37	GO:0045177	apical part of cell
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V7P1|UTP18_DROME
U3 small nucleolar RNA-associated protein 18 homolog
Search

0.59	U3 small nucleolar RNA-associated protein 18

0.86	GO:0048132	female germ-line stem cell asymmetric division
0.85	GO:0007405	neuroblast proliferation
0.68	GO:0006364	rRNA processing
0.46	GO:0042274	ribosomal small subunit biogenesis
0.37	GO:0034471	ncRNA 5'-end processing
0.36	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.34	GO:0051568	histone H3-K4 methylation

0.34	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.33	GO:0003723	RNA binding

0.87	GO:0042585	germinal vesicle
0.78	GO:0030532	small nuclear ribonucleoprotein complex
0.73	GO:0005730	nucleolus
0.48	GO:0030686	90S preribosome
0.47	GO:0032040	small-subunit processome
0.41	GO:0043234	protein complex

sp|Q9V7S5|PICO_DROME
Putative inorganic phosphate cotransporter
Search

0.38	Inorganic phosphate co-transporter

0.55	GO:0055085	transmembrane transport
0.50	GO:0006817	phosphate ion transport
0.36	GO:0006814	sodium ion transport
0.32	GO:0006508	proteolysis

0.52	GO:0015114	phosphate ion transmembrane transporter activity
0.36	GO:0015293	symporter activity
0.33	GO:0008236	serine-type peptidase activity

0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V7U0|RESIL_DROME
Pro-resilin
Search

0.56	Pro-resilin

0.41	GO:0040003	chitin-based cuticle development
0.36	GO:0006030	chitin metabolic process
0.33	GO:0006508	proteolysis
0.32	GO:0001522	pseudouridine synthesis
0.32	GO:0010951	negative regulation of endopeptidase activity
0.32	GO:0006413	translational initiation
0.32	GO:1902600	hydrogen ion transmembrane transport
0.32	GO:0022900	electron transport chain
0.32	GO:0005975	carbohydrate metabolic process

0.74	GO:0042302	structural constituent of cuticle
0.70	GO:0030023	extracellular matrix constituent conferring elasticity
0.59	GO:0008061	chitin binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0003723	RNA binding
0.32	GO:0009982	pseudouridine synthase activity
0.32	GO:0004867	serine-type endopeptidase inhibitor activity
0.32	GO:0015002	heme-copper terminal oxidase activity
0.32	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor

0.70	GO:0032992	protein-carbohydrate complex
0.39	GO:0031012	extracellular matrix
0.32	GO:0005746	mitochondrial respiratory chain
0.32	GO:0019028	viral capsid
0.32	GO:0005615	extracellular space
0.31	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

GO:0004222

sp|Q9V7W1|PIGV_DROME
GPI mannosyltransferase 2
Search

0.58	GPI mannosyltransferase 2

0.78	GO:0006506	GPI anchor biosynthetic process
0.78	GO:0097502	mannosylation
0.61	GO:0045052	protein insertion into ER membrane by GPI attachment sequence
0.60	GO:0045313	rhabdomere membrane biogenesis

0.83

GO:0004584

dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity

0.71	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0031501	mannosyltransferase complex
0.30	GO:0016021	integral component of membrane

0.83

EC:2.4.1.130

GO:0004584

tr|Q9V7W9|Q9V7W9_DROME
Nuclear inhibitor of protein phosphatase 1
Search

0.86	Nuclear inhibitor of protein phosphatase

0.77	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.73	GO:0007411	axon guidance
0.54	GO:0031204	posttranslational protein targeting to membrane, translocation
0.35	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.35	GO:0016311	dephosphorylation
0.33	GO:0007165	signal transduction

0.80	GO:0004865	protein serine/threonine phosphatase inhibitor activity
0.78	GO:0008157	protein phosphatase 1 binding
0.70	GO:0003729	mRNA binding
0.36	GO:0008253	5'-nucleotidase activity
0.35	GO:0008527	taste receptor activity
0.34	GO:0000287	magnesium ion binding

0.75	GO:0016607	nuclear speck
0.51	GO:0030176	integral component of endoplasmic reticulum membrane

0.36

EC:3.1.3.5

GO:0008253

sp|Q9V7Y2|SGPL_DROME
Sphingosine-1-phosphate lyase
Search

0.60	Pyridoxal-dependent decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.49	GO:0007527	adult somatic muscle development
0.48	GO:0030149	sphingolipid catabolic process
0.37	GO:0001553	luteinization
0.37	GO:0033327	Leydig cell differentiation
0.37	GO:0010761	fibroblast migration
0.37	GO:0008209	androgen metabolic process
0.37	GO:0008210	estrogen metabolic process
0.37	GO:0060325	face morphogenesis
0.37	GO:0048008	platelet-derived growth factor receptor signaling pathway

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.51	GO:0008117	sphinganine-1-phosphate aldolase activity
0.33	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.33	GO:0070546	L-phenylalanine aminotransferase activity

0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.68	EC:4.1.1	GO:0016831
0.33	KEGG:R00355	GO:0004069

sp|Q9V813|MTAP_DROME
S-methyl-5'-thioadenosine phosphorylase
Search

MTAP

0.54	Purine nucleoside phosphorylase

0.72	GO:0006166	purine ribonucleoside salvage
0.71	GO:0019509	L-methionine salvage from methylthioadenosine
0.34	GO:0032259	methylation
0.33	GO:0015991	ATP hydrolysis coupled proton transport

0.82	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity
0.44	GO:0042802	identical protein binding
0.34	GO:0004104	cholinesterase activity
0.32	GO:0015078	hydrogen ion transmembrane transporter activity

0.58	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.33	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.30	GO:0016021	integral component of membrane

0.82

EC:2.4.2.28

GO:0017061

sp|Q9V817|MTH4_DROME
Probable G-protein coupled receptor Mth-like 4
Search

0.73	G-protein coupled receptor Mth

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0007166	cell surface receptor signaling pathway
0.61	GO:0006950	response to stress
0.46	GO:0008340	determination of adult lifespan
0.44	GO:0031667	response to nutrient levels
0.36	GO:0016079	synaptic vesicle exocytosis
0.35	GO:0009266	response to temperature stimulus
0.35	GO:0042221	response to chemical
0.34	GO:0007608	sensory perception of smell
0.34	GO:0050906	detection of stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.35	GO:0042277	peptide binding
0.35	GO:0001653	peptide receptor activity
0.35	GO:0005549	odorant binding
0.34	GO:0004984	olfactory receptor activity
0.34	GO:0005515	protein binding

0.38	GO:0005886	plasma membrane
0.35	GO:0098793	presynapse
0.30	GO:0016021	integral component of membrane

sp|Q9V818|MTH3_DROME
Probable G-protein coupled receptor Mth-like 3
Search

0.74	G-protein coupled receptor Mth

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0007166	cell surface receptor signaling pathway
0.61	GO:0006950	response to stress
0.46	GO:0008340	determination of adult lifespan
0.43	GO:0031667	response to nutrient levels
0.36	GO:0016079	synaptic vesicle exocytosis
0.35	GO:0009266	response to temperature stimulus
0.35	GO:0042221	response to chemical
0.34	GO:0007608	sensory perception of smell
0.34	GO:0050906	detection of stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.35	GO:0042277	peptide binding
0.35	GO:0001653	peptide receptor activity
0.35	GO:0005549	odorant binding
0.34	GO:0004984	olfactory receptor activity
0.34	GO:0005515	protein binding
0.32	GO:0043565	sequence-specific DNA binding

0.38	GO:0005886	plasma membrane
0.35	GO:0098793	presynapse
0.31	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q9V831|APC10_DROME
Anaphase-promoting complex subunit 10
Search

0.78	Anaphase-promoting complex subunit 10

0.83	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.64	GO:0051301	cell division
0.64	GO:0007049	cell cycle
0.53	GO:0070979	protein K11-linked ubiquitination
0.46	GO:2000736	regulation of stem cell differentiation
0.45	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.36	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.34	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.34	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.43	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0016853	isomerase activity
0.33	GO:0004518	nuclease activity
0.32	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.80	GO:0005680	anaphase-promoting complex
0.37	GO:0005737	cytoplasm
0.35	GO:0031248	protein acetyltransferase complex
0.33	GO:0005654	nucleoplasm

0.33

GO:0016853

sp|Q9V853|SMUF1_DROME
E3 ubiquitin-protein ligase Smurf1
Search

0.47	SMAD specific E3 ubiquitin protein ligase, isoform B

0.73	GO:0016567	protein ubiquitination
0.68	GO:0006511	ubiquitin-dependent protein catabolic process
0.54	GO:0030514	negative regulation of BMP signaling pathway
0.54	GO:0008101	decapentaplegic signaling pathway
0.53	GO:0048619	embryonic hindgut morphogenesis
0.52	GO:0007293	germarium-derived egg chamber formation
0.52	GO:0001700	embryonic development via the syncytial blastoderm
0.50	GO:0040008	regulation of growth
0.45	GO:0010629	negative regulation of gene expression
0.40	GO:0061753	substrate localization to autophagosome

0.73	GO:0004842	ubiquitin-protein transferase activity
0.68	GO:0061659	ubiquitin-like protein ligase activity
0.53	GO:0016874	ligase activity
0.39	GO:0070411	I-SMAD binding
0.39	GO:0070412	R-SMAD binding
0.34	GO:0051920	peroxiredoxin activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.38	GO:0005737	cytoplasm
0.37	GO:0000151	ubiquitin ligase complex
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.34	GO:0045121	membrane raft
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q9V877|SUB_DROME
Kinesin-like protein subito
Search

SUB

0.96	Kinesin-like protein subito

0.74	GO:0007018	microtubule-based movement
0.60	GO:0051257	meiotic spindle midzone assembly
0.60	GO:0007091	metaphase/anaphase transition of mitotic cell cycle
0.59	GO:0040016	embryonic cleavage
0.59	GO:0016321	female meiosis chromosome segregation
0.57	GO:0000212	meiotic spindle organization
0.57	GO:0007140	male meiotic nuclear division
0.55	GO:0007052	mitotic spindle organization
0.40	GO:0018108	peptidyl-tyrosine phosphorylation
0.35	GO:0044837	actomyosin contractile ring organization

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004713	protein tyrosine kinase activity
0.36	GO:0016887	ATPase activity
0.33	GO:0003873	6-phosphofructo-2-kinase activity
0.32	GO:0003938	IMP dehydrogenase activity
0.31	GO:0046872	metal ion binding

0.66	GO:0005874	microtubule
0.56	GO:0051233	spindle midzone
0.54	GO:0000922	spindle pole
0.53	GO:0005875	microtubule associated complex
0.34	GO:0009524	phragmoplast
0.30	GO:0031224	intrinsic component of membrane

0.40	EC:2.7.10	GO:0004713
0.33	KEGG:R02732	GO:0003873

sp|Q9V895|AN32A_DROME
Acidic leucine-rich nuclear phosphoprotein 32 family member A
Search

0.83	Acidic leucine-rich nuclear phosphoprotein 32 family member A

0.64	GO:0043486	histone exchange
0.61	GO:0006334	nucleosome assembly
0.59	GO:0006913	nucleocytoplasmic transport
0.58	GO:0042981	regulation of apoptotic process
0.43	GO:0007017	microtubule-based process
0.38	GO:0035556	intracellular signal transduction

0.61	GO:0042393	histone binding
0.44	GO:0008017	microtubule binding
0.36	GO:0046872	metal ion binding
0.35	GO:0003676	nucleic acid binding

0.53	GO:0005634	nucleus
0.51	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005783	endoplasmic reticulum
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0005875	microtubule associated complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9V8F3|U279_DROME
UPF0279 protein CG14505
Search

0.82

GO:0060828

regulation of canonical Wnt signaling pathway

0.85

GO:0051018

protein kinase A binding

sp|Q9V8F5|IM23_DROME
Immune-induced peptide 23
Search

0.96	Immune-induced peptide 23

0.85	GO:0019731	antibacterial humoral response
0.85	GO:0050830	defense response to Gram-positive bacterium
0.51	GO:0008063	Toll signaling pathway
0.48	GO:0045087	innate immune response

0.66

GO:0005576

extracellular region

sp|Q9V8G0|IM03_DROME
Immune-induced peptide 3
Search

0.73	GO:0019731	antibacterial humoral response
0.50	GO:0045087	innate immune response
0.45	GO:0008063	Toll signaling pathway

0.64	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q9V8I2|LTOR2_DROME
Ragulator complex protein LAMTOR2 homolog
Search

LAMTOR2

0.92	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

0.81	GO:0032008	positive regulation of TOR signaling
0.66	GO:0065009	regulation of molecular function
0.57	GO:0071230	cellular response to amino acid stimulus
0.49	GO:0001558	regulation of cell growth
0.47	GO:0043410	positive regulation of MAPK cascade
0.45	GO:0034613	cellular protein localization
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0016241	regulation of macroautophagy
0.34	GO:0007050	cell cycle arrest
0.34	GO:0000165	MAPK cascade

0.81	GO:0032947	protein complex scaffold activity
0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.53	GO:0071986	Ragulator complex
0.41	GO:0005765	lysosomal membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004553

sp|Q9V8K2|EXOC3_DROME
Exocyst complex component 3
Search

0.62	Exocyst complex component

0.77	GO:0006887	exocytosis
0.51	GO:0045313	rhabdomere membrane biogenesis
0.49	GO:0072697	protein localization to cell cortex
0.49	GO:0007298	border follicle cell migration
0.49	GO:0043001	Golgi to plasma membrane protein transport
0.48	GO:0032456	endocytic recycling
0.47	GO:0007009	plasma membrane organization
0.45	GO:0051601	exocyst localization
0.36	GO:0006903	vesicle targeting
0.36	GO:0097480	establishment of synaptic vesicle localization

0.43	GO:0000149	SNARE binding
0.40	GO:0045296	cadherin binding
0.32	GO:0003677	DNA binding
0.32	GO:0016491	oxidoreductase activity

0.79	GO:0000145	exocyst
0.50	GO:0016028	rhabdomere
0.50	GO:0005915	zonula adherens
0.36	GO:0097458	neuron part
0.35	GO:0044456	synapse part
0.33	GO:0030496	midbody
0.33	GO:0030427	site of polarized growth
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005794	Golgi apparatus

0.32