Queries 3001 to 4000

GO:0016787

sp|P25843|PROF_DROME
Profilin
Search

0.71

Profilin

0.51	GO:0035193	larval central nervous system remodeling
0.50	GO:0048842	positive regulation of axon extension involved in axon guidance
0.50	GO:0007436	larval salivary gland morphogenesis
0.49	GO:0007488	histoblast morphogenesis
0.49	GO:0036098	male germ-line stem cell population maintenance
0.49	GO:0048680	positive regulation of axon regeneration
0.49	GO:0030717	karyosome formation
0.48	GO:0016322	neuron remodeling
0.48	GO:0051491	positive regulation of filopodium assembly
0.48	GO:0035019	somatic stem cell population maintenance

0.74	GO:0003779	actin binding
0.34	GO:0070064	proline-rich region binding
0.34	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.33	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0004004	ATP-dependent RNA helicase activity
0.32	GO:0003743	translation initiation factor activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005856	cytoskeleton
0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0043005	neuron projection
0.38	GO:0005938	cell cortex
0.33	GO:0051286	cell tip
0.33	GO:0043332	mating projection tip
0.33	GO:0005794	Golgi apparatus
0.33	GO:0032155	cell division site part
0.33	GO:0019897	extrinsic component of plasma membrane
0.33	GO:0005829	cytosol

sp|P25867|UBCD1_DROME
Ubiquitin-conjugating enzyme E2-17 kDa
Search

0.47	Ubiquitin-conjugating enzyme

0.48	GO:0000209	protein polyubiquitination
0.45	GO:0051865	protein autoubiquitination
0.44	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.44	GO:0045676	regulation of R7 cell differentiation
0.43	GO:0048132	female germ-line stem cell asymmetric division
0.43	GO:0016322	neuron remodeling
0.43	GO:0030718	germ-line stem cell population maintenance
0.42	GO:0001751	compound eye photoreceptor cell differentiation
0.42	GO:0007140	male meiotic nuclear division
0.42	GO:0031145	anaphase-promoting complex-dependent catabolic process

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0061631	ubiquitin conjugating enzyme activity
0.43	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0016874	ligase activity

0.42	GO:0000151	ubiquitin ligase complex
0.38	GO:0043234	protein complex
0.35	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0005694	chromosome
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.37

GO:0016874

sp|P25931|RYAR_DROME
RYamide receptor
Search

0.38	Queuine tRNA-ribosyltransferase

0.75	GO:0007218	neuropeptide signaling pathway
0.39	GO:0007217	tachykinin receptor signaling pathway
0.36	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0007211	octopamine or tyramine signaling pathway
0.34	GO:0071875	adrenergic receptor signaling pathway
0.34	GO:1901652	response to peptide
0.34	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.34	GO:0032870	cellular response to hormone stimulus
0.34	GO:0002027	regulation of heart rate
0.34	GO:0098664	G-protein coupled serotonin receptor signaling pathway

0.78	GO:0004983	neuropeptide Y receptor activity
0.40	GO:0004995	tachykinin receptor activity
0.36	GO:0008227	G-protein coupled amine receptor activity
0.35	GO:0050254	rhodopsin kinase activity
0.34	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.34	GO:0042277	peptide binding
0.34	GO:0051378	serotonin binding
0.34	GO:0099589	serotonin receptor activity
0.33	GO:0051379	epinephrine binding

0.37	GO:0005886	plasma membrane
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.11.14

GO:0050254

sp|P25932|ESCA_DROME
Protein escargot
Search

0.69	Escargot/snail protein homolog

0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0007489	maintenance of imaginal histoblast diploidy
0.54	GO:0048076	regulation of compound eye pigmentation
0.54	GO:0035921	desmosome disassembly
0.54	GO:0055059	asymmetric neuroblast division
0.54	GO:0070563	negative regulation of vitamin D receptor signaling pathway
0.53	GO:0035147	branch fusion, open tracheal system
0.53	GO:0007427	epithelial cell migration, open tracheal system
0.53	GO:0042332	gravitaxis
0.53	GO:0032876	negative regulation of DNA endoreduplication

0.59	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.41	GO:0003682	chromatin binding
0.37	GO:0005507	copper ion binding
0.34	GO:0005515	protein binding

0.48	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.38	GO:0005667	transcription factor complex
0.35	GO:0005737	cytoplasm

sp|P25991|SUF_DROME
Protein suppressor of forked
Search

0.74	Cleavage stimulation factor

0.70	GO:0006397	mRNA processing
0.51	GO:1903220	positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity
0.42	GO:0006379	mRNA cleavage
0.41	GO:0031123	RNA 3'-end processing
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0043631	RNA polyadenylation
0.33	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.33	GO:0055085	transmembrane transport
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.41	GO:0003729	mRNA binding
0.34	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.39	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P25992|YEMA_DROME
yemanuclein
Search

0.93	yemanuclein-alpha

0.69	GO:0006325	chromatin organization
0.62	GO:0035039	male pronucleus assembly
0.60	GO:0007143	female meiotic nuclear division
0.55	GO:0071824	protein-DNA complex subunit organization
0.36	GO:0006323	DNA packaging
0.35	GO:0034622	cellular macromolecular complex assembly
0.34	GO:0090501	RNA phosphodiester bond hydrolysis
0.33	GO:0006396	RNA processing

0.43	GO:0003677	DNA binding
0.40	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0.39	GO:0046872	metal ion binding
0.34	GO:0004540	ribonuclease activity
0.33	GO:0003723	RNA binding

0.63	GO:0042585	germinal vesicle
0.63	GO:0001940	male pronucleus
0.56	GO:0000777	condensed chromosome kinetochore
0.52	GO:0005654	nucleoplasm
0.37	GO:0005923	bicellular tight junction

0.40

EC:3.6.1

GO:0016818

sp|P26016|FUR11_DROME
Furin-like protease 1, isoforms 1/1-X/2
Search

0.88	Vitellogenin convertase

0.60	GO:0006508	proteolysis
0.39	GO:0097688	glutamate receptor clustering
0.39	GO:0097090	presynaptic membrane organization
0.39	GO:0008039	synaptic target recognition
0.39	GO:0001941	postsynaptic membrane organization

0.69	GO:0004252	serine-type endopeptidase activity
0.32	GO:0046872	metal ion binding

0.37	GO:0000139	Golgi membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P26017|PC_DROME
Polycomb group protein Pc
Search

0.75	Polycomb group protein Pc

0.69	GO:0007385	specification of segmental identity, abdomen
0.68	GO:2001229	negative regulation of response to gamma radiation
0.67	GO:0035186	syncytial blastoderm mitotic cell cycle
0.64	GO:0016322	neuron remodeling
0.60	GO:0042060	wound healing
0.58	GO:0016458	gene silencing
0.55	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0007419	ventral cord development

0.62	GO:0140034	methylation-dependent protein binding
0.59	GO:0042393	histone binding
0.58	GO:0003682	chromatin binding
0.32	GO:0016874	ligase activity

0.64	GO:0035102	PRC1 complex
0.55	GO:0005730	nucleolus
0.55	GO:0000785	chromatin
0.39	GO:0044454	nuclear chromosome part
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016874

sp|P26019|DPOLA_DROME
DNA polymerase alpha catalytic subunit
Search

POLA1

0.47	DNA polymerase alpha catalytic subunit

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0022616	DNA strand elongation
0.41	GO:0006303	double-strand break repair via nonhomologous end joining
0.35	GO:0016070	RNA metabolic process
0.34	GO:0070914	UV-damage excision repair
0.34	GO:0008283	cell proliferation
0.34	GO:0045596	negative regulation of cell differentiation
0.34	GO:0032981	mitochondrial respiratory chain complex I assembly

0.72	GO:0008408	3'-5' exonuclease activity
0.71	GO:0003887	DNA-directed DNA polymerase activity
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.64	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.37	GO:0046982	protein heterodimerization activity
0.37	GO:0008852	exodeoxyribonuclease I activity
0.34	GO:0030337	DNA polymerase processivity factor activity

0.60	GO:0005634	nucleus
0.50	GO:0000428	DNA-directed RNA polymerase complex
0.50	GO:0030894	replisome
0.47	GO:0031974	membrane-enclosed lumen
0.36	GO:0005829	cytosol
0.33	GO:0000785	chromatin
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.30	GO:0016020	membrane

0.71

GO:0003887

sp|P26023|PIG1_DROME
Pre-intermoult gene 1 protein
Search

0.64	GO:0006413	translational initiation
0.44	GO:0016071	mRNA metabolic process
0.44	GO:0006396	RNA processing
0.42	GO:0006401	RNA catabolic process
0.41	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.41	GO:0016072	rRNA metabolic process
0.40	GO:0010629	negative regulation of gene expression
0.40	GO:0042254	ribosome biogenesis
0.39	GO:0006399	tRNA metabolic process
0.38	GO:0018993	somatic sex determination

0.64	GO:0003743	translation initiation factor activity
0.61	GO:0003924	GTPase activity
0.59	GO:0032550	purine ribonucleoside binding
0.59	GO:0019001	guanyl nucleotide binding
0.50	GO:0032555	purine ribonucleotide binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0008995	ribonuclease E activity
0.41	GO:0004521	endoribonuclease activity
0.39	GO:0000287	magnesium ion binding
0.39	GO:0008270	zinc ion binding

0.46	GO:0005737	cytoplasm
0.43	GO:0009898	cytoplasmic side of plasma membrane
0.36	GO:0005576	extracellular region
0.34	GO:0005634	nucleus

sp|P26270|PSMD7_DROME
26S proteasome non-ATPase regulatory subunit 7
Search

0.70	Maintenance of mitochondrial structure and function

0.43	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:0021551	central nervous system morphogenesis
0.40	GO:1904888	cranial skeletal system development
0.35	GO:0008063	Toll signaling pathway
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0016567	protein ubiquitination
0.35	GO:0038095	Fc-epsilon receptor signaling pathway

0.45	GO:0042803	protein homodimerization activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0003779	actin binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.81	GO:0005838	proteasome regulatory particle
0.43	GO:0005654	nucleoplasm
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005829	cytosol
0.34	GO:0030425	dendrite
0.34	GO:0070062	extracellular exosome
0.34	GO:0016459	myosin complex
0.30	GO:0016020	membrane

sp|P26308|GBB1_DROME
Guanine nucleotide-binding protein subunit beta-1
Search

0.68	Heterotrimeric guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.46	GO:0003371	establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration
0.46	GO:0003379	establishment of cell polarity involved in gastrulation cell migration
0.46	GO:0048383	mesectoderm development
0.46	GO:0043519	regulation of myosin II filament organization
0.45	GO:0061343	cell adhesion involved in heart morphogenesis
0.45	GO:0055059	asymmetric neuroblast division
0.45	GO:0060027	convergent extension involved in gastrulation
0.44	GO:0010470	regulation of gastrulation
0.41	GO:0046662	regulation of oviposition

0.35	GO:0004402	histone acetyltransferase activity
0.35	GO:0004871	signal transducer activity
0.34	GO:0005516	calmodulin binding
0.34	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0003743	translation initiation factor activity

0.43	GO:1905360	GTPase complex
0.43	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0098797	plasma membrane protein complex
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004402

sp|P26675|SOS_DROME
Protein son of sevenless
Search

0.85	Ras GTP exchange factor, son of sevenless

0.77	GO:0035023	regulation of Rho protein signal transduction
0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.56	GO:0035022	positive regulation of Rac protein signal transduction
0.55	GO:0007426	tracheal outgrowth, open tracheal system
0.55	GO:0016199	axon midline choice point recognition
0.54	GO:0007480	imaginal disc-derived leg morphogenesis
0.53	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.40	GO:0001654	eye development
0.40	GO:1904693	midbrain morphogenesis

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.73	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.53	GO:0048365	Rac GTPase binding
0.34	GO:0017124	SH3 domain binding
0.33	GO:0016831	carboxy-lyase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.33	GO:0003735	structural constituent of ribosome

0.59	GO:0000786	nucleosome
0.51	GO:0005634	nucleus
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0005737	cytoplasm
0.34	GO:0014069	postsynaptic density
0.34	GO:0043025	neuronal cell body
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.33

EC:4.1.1

GO:0016831

sp|P26686|SRR55_DROME
Serine-arginine protein 55
Search

0.39	Arginine/serine-rich splicing factor

0.37	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.37	GO:0031440	regulation of mRNA 3'-end processing
0.36	GO:0044819	mitotic G1/S transition checkpoint
0.36	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.35	GO:0051607	defense response to virus
0.35	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation

0.58	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.37	GO:0035062	omega speckle
0.36	GO:0035327	transcriptionally active chromatin
0.36	GO:0071011	precatalytic spliceosome
0.36	GO:0005700	polytene chromosome
0.36	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.3

GO:0008138

sp|P26802|DDX51_DROME
Probable ATP-dependent RNA helicase Dbp73D
Search

0.39	DEAD/DEAH box helicase

0.41	GO:0010501	RNA secondary structure unwinding
0.37	GO:0006364	rRNA processing
0.35	GO:1902626	assembly of large subunit precursor of preribosome
0.34	GO:0042273	ribosomal large subunit biogenesis
0.34	GO:0030522	intracellular receptor signaling pathway
0.34	GO:0043401	steroid hormone mediated signaling pathway
0.34	GO:0034471	ncRNA 5'-end processing
0.33	GO:0042274	ribosomal small subunit biogenesis
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.32	GO:0006351	transcription, DNA-templated

0.66	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0008186	RNA-dependent ATPase activity
0.38	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0004887	thyroid hormone receptor activity
0.34	GO:0042802	identical protein binding
0.34	GO:0003707	steroid hormone receptor activity

0.40	GO:0005730	nucleolus
0.35	GO:0030687	preribosome, large subunit precursor
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P27091|60A_DROME
Protein 60A
Search

0.72	TGF-beta propeptide

0.75	GO:0010469	regulation of receptor activity
0.55	GO:0030855	epithelial cell differentiation
0.54	GO:0060562	epithelial tube morphogenesis
0.54	GO:0051094	positive regulation of developmental process
0.54	GO:0007389	pattern specification process
0.54	GO:0048468	cell development
0.54	GO:0035107	appendage morphogenesis
0.54	GO:0009887	animal organ morphogenesis
0.53	GO:0036099	female germ-line stem cell population maintenance
0.53	GO:0051960	regulation of nervous system development

0.78	GO:0008083	growth factor activity
0.49	GO:0070700	BMP receptor binding
0.46	GO:0005160	transforming growth factor beta receptor binding
0.45	GO:0005125	cytokine activity
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0008201	heparin binding
0.35	GO:0047453	ATP-dependent NAD(P)H-hydrate dehydratase activity
0.34	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.55	GO:0097467	type III terminal bouton
0.53	GO:0031045	dense core granule
0.30	GO:0016020	membrane

0.35	EC:4.2.1.93	GO:0047453
0.35	KEGG:R00129	GO:0047453

sp|P27398|CAND_DROME
Calpain-D
Search

LOC108092791

0.71

Calpain-D

0.60	GO:0006508	proteolysis
0.47	GO:0007399	nervous system development
0.40	GO:0080009	mRNA methylation
0.39	GO:0006370	7-methylguanosine mRNA capping
0.37	GO:0007601	visual perception
0.34	GO:0050896	response to stimulus
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0006355	regulation of transcription, DNA-templated

0.81	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.52	GO:0046872	metal ion binding
0.41	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
0.35	GO:0003676	nucleic acid binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005622	intracellular
0.33	GO:0043226	organelle
0.33	GO:1990904	ribonucleoprotein complex
0.30	GO:0016020	membrane

0.41

EC:2.1.1.57

GO:0004483

sp|P27619|DYN_DROME
Dynamin
Search

0.67

Dynamin

0.52	GO:0072583	clathrin-dependent endocytosis
0.37	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.36	GO:0000266	mitochondrial fission
0.36	GO:0046667	compound eye retinal cell programmed cell death
0.36	GO:0048499	synaptic vesicle membrane organization
0.36	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane
0.36	GO:0007637	proboscis extension reflex
0.35	GO:0001661	conditioned taste aversion
0.35	GO:0035186	syncytial blastoderm mitotic cell cycle
0.35	GO:0007296	vitellogenesis

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.35	GO:0008017	microtubule binding
0.34	GO:0003779	actin binding
0.33	GO:0004721	phosphoprotein phosphatase activity

0.35	GO:0070864	sperm individualization complex
0.34	GO:0072686	mitotic spindle
0.34	GO:0098793	presynapse
0.34	GO:0005874	microtubule
0.34	GO:0031966	mitochondrial membrane
0.32	GO:0005886	plasma membrane

0.33

GO:0004721

sp|P27716|INX1_DROME
Innexin inx1
Search

INX

0.66

Innexin

0.59	GO:0006811	ion transport
0.46	GO:0007602	phototransduction
0.42	GO:0010496	intercellular transport
0.41	GO:0036098	male germ-line stem cell population maintenance
0.41	GO:0030727	germarium-derived female germ-line cyst formation
0.41	GO:0007440	foregut morphogenesis
0.40	GO:0016331	morphogenesis of embryonic epithelium
0.39	GO:0007283	spermatogenesis
0.36	GO:0055085	transmembrane transport
0.36	GO:0007632	visual behavior

0.43

GO:0005243

gap junction channel activity

0.81	GO:0005921	gap junction
0.56	GO:0005886	plasma membrane
0.39	GO:0045177	apical part of cell
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P27779|CUP7_DROME
Pupal cuticle protein Edg-78E
Search

0.97	Pupal cuticle protein Edg-78E

0.41

GO:0040003

chitin-based cuticle development

0.79

GO:0042302

structural constituent of cuticle

0.39	GO:0031012	extracellular matrix
0.30	GO:0044425	membrane part

sp|P27780|CUP8_DROME
Pupal cuticle protein Edg-84A
Search

0.55	Pupal cuticle protein Edg-84A

0.39	GO:0040003	chitin-based cuticle development
0.34	GO:0048598	embryonic morphogenesis

0.78

GO:0042302

structural constituent of cuticle

0.37	GO:0031012	extracellular matrix
0.34	GO:0072669	tRNA-splicing ligase complex
0.30	GO:0044425	membrane part

sp|P27781|CUP9_DROME
Pupal cuticle protein Edg-91
Search

0.50	GO:0010466	negative regulation of peptidase activity
0.42	GO:0061059	positive regulation of peptidoglycan recognition protein signaling pathway
0.41	GO:0002252	immune effector process
0.41	GO:0061057	peptidoglycan recognition protein signaling pathway
0.41	GO:0051260	protein homooligomerization
0.40	GO:0050830	defense response to Gram-positive bacterium
0.40	GO:0050829	defense response to Gram-negative bacterium
0.39	GO:0061436	establishment of skin barrier
0.39	GO:0050728	negative regulation of inflammatory response
0.39	GO:0009615	response to virus

0.51	GO:0008011	structural constituent of pupal chitin-based cuticle
0.51	GO:0030414	peptidase inhibitor activity
0.43	GO:0003723	RNA binding
0.40	GO:0030280	structural constituent of epidermis
0.39	GO:0004386	helicase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0032553	ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004812	aminoacyl-tRNA ligase activity

0.48	GO:0005576	extracellular region
0.40	GO:0005581	collagen trimer
0.39	GO:0001533	cornified envelope
0.38	GO:0045095	keratin filament
0.37	GO:0005618	cell wall
0.36	GO:0005680	anaphase-promoting complex
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.37	EC:6.1.1	GO:0004812
0.37	KEGG:R02133	GO:0050334

sp|P27864|RRP1_DROME
Recombination repair protein 1
Search

0.52	Recombination repair protein 1

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.51	GO:0043247	telomere maintenance in response to DNA damage
0.51	GO:0080111	DNA demethylation
0.51	GO:0043488	regulation of mRNA stability
0.47	GO:0042981	regulation of apoptotic process
0.44	GO:0045454	cell redox homeostasis
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:0055114	oxidation-reduction process
0.40	GO:0014912	negative regulation of smooth muscle cell migration

0.75	GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) lyase activity
0.75	GO:0140078	class I DNA-(apurinic or apyrimidinic site) lyase activity
0.66	GO:0004519	endonuclease activity
0.55	GO:0003677	DNA binding
0.54	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.53	GO:0046872	metal ion binding
0.48	GO:0008408	3'-5' exonuclease activity
0.48	GO:0003713	transcription coactivator activity
0.48	GO:0003682	chromatin binding
0.46	GO:0008081	phosphoric diester hydrolase activity

0.49	GO:0005634	nucleus
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005739	mitochondrion
0.48	GO:0005813	centrosome
0.44	GO:0031974	membrane-enclosed lumen
0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0005667	transcription factor complex
0.34	GO:0000781	chromosome, telomeric region
0.33	GO:0005840	ribosome

0.46

EC:3.1.4

GO:0008081

sp|P28159|SUH_DROME
Suppressor of hairless protein
Search

0.74	Recombination signal binding protein for immunoglobulin kappa J region

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0048645	animal organ formation
0.49	GO:0045165	cell fate commitment
0.49	GO:0003002	regionalization
0.48	GO:0035295	tube development
0.48	GO:0007219	Notch signaling pathway
0.48	GO:0042688	crystal cell differentiation
0.48	GO:0060429	epithelium development
0.47	GO:0007423	sensory organ development
0.47	GO:0048729	tissue morphogenesis

0.80	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.80	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0001085	RNA polymerase II transcription factor binding
0.48	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.45	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.42	GO:0070491	repressing transcription factor binding
0.42	GO:0047485	protein N-terminus binding
0.40	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.48	GO:0017053	transcriptional repressor complex
0.46	GO:0005700	polytene chromosome
0.43	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.39	GO:0005667	transcription factor complex
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0005737	cytoplasm
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P28166|ZFH1_DROME
Zinc finger protein 1
Search

0.56	Zinc finger protein 1

0.52	GO:2001141	regulation of RNA biosynthetic process
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.46	GO:0007411	axon guidance
0.44	GO:0061321	garland nephrocyte differentiation
0.44	GO:0007516	hemocyte development
0.44	GO:0007280	pole cell migration
0.43	GO:0048542	lymph gland development
0.43	GO:0048103	somatic stem cell division
0.42	GO:0045773	positive regulation of axon extension

0.59	GO:0043565	sequence-specific DNA binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.36	GO:0046872	metal ion binding

0.60

GO:0005634

nucleus

sp|P28167|ZFH2_DROME
Zinc finger protein 2
Search

0.48	LOW QUALITY PROTEIN: zinc finger protein 2

0.61	GO:0007476	imaginal disc-derived wing morphogenesis
0.55	GO:0007399	nervous system development
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression

0.62	GO:0043565	sequence-specific DNA binding
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0003690	double-stranded DNA binding
0.53	GO:0008270	zinc ion binding

0.60

GO:0005634

nucleus

sp|P28285|5HT2A_DROME
5-hydroxytryptamine receptor 2A
Search

0.54	5-hydroxytryptamine receptor 2A

0.74	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway
0.73	GO:0007615	anesthesia-resistant memory
0.72	GO:0002121	inter-male aggressive behavior
0.72	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway
0.70	GO:0008049	male courtship behavior
0.70	GO:0045187	regulation of circadian sleep/wake cycle, sleep

0.72	GO:0004930	G-protein coupled receptor activity
0.68	GO:0099589	serotonin receptor activity
0.62	GO:0030594	neurotransmitter receptor activity

0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P28286|5HT2B_DROME
5-hydroxytryptamine receptor 2B
Search

0.58	5-hydroxytryptamine receptor 1A-beta

0.75	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway
0.73	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway
0.67	GO:0042752	regulation of circadian rhythm
0.54	GO:0007615	anesthesia-resistant memory
0.53	GO:0002121	inter-male aggressive behavior
0.52	GO:0008049	male courtship behavior
0.51	GO:0009605	response to external stimulus
0.50	GO:0050795	regulation of behavior
0.46	GO:0051239	regulation of multicellular organismal process
0.36	GO:0071928	tyramine signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.68	GO:0099589	serotonin receptor activity
0.62	GO:0030594	neurotransmitter receptor activity
0.32	GO:0003677	DNA binding

0.36	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P28465|WNT2_DROME
Protein Wnt-2
Search

0.10	Proto-oncogene Wnt-3

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.55	GO:0009653	anatomical structure morphogenesis
0.54	GO:0030154	cell differentiation
0.54	GO:0120036	plasma membrane bounded cell projection organization
0.50	GO:0045596	negative regulation of cell differentiation
0.50	GO:0016049	cell growth
0.50	GO:0045597	positive regulation of cell differentiation
0.50	GO:0048589	developmental growth
0.50	GO:0061061	muscle structure development

0.73	GO:0005102	receptor binding
0.49	GO:0030545	receptor regulator activity
0.45	GO:0019904	protein domain specific binding
0.34	GO:0039706	co-receptor binding
0.34	GO:0019992	diacylglycerol binding
0.34	GO:0003713	transcription coactivator activity
0.32	GO:0005543	phospholipid binding
0.32	GO:0046872	metal ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.44	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.35	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.34	GO:1990909	Wnt signalosome
0.34	GO:0005796	Golgi lumen
0.34	GO:0030666	endocytic vesicle membrane
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P28466|WNT5_DROME
Protein Wnt-5
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.59	GO:0050919	negative chemotaxis
0.58	GO:0061387	regulation of extent of cell growth
0.58	GO:0050921	positive regulation of chemotaxis
0.57	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.56	GO:0060560	developmental growth involved in morphogenesis
0.56	GO:0016358	dendrite development
0.56	GO:0031346	positive regulation of cell projection organization
0.56	GO:0048588	developmental cell growth

0.72	GO:0005102	receptor binding
0.37	GO:0044212	transcription regulatory region DNA binding
0.37	GO:0019904	protein domain specific binding
0.36	GO:0030545	receptor regulator activity
0.35	GO:0003700	DNA binding transcription factor activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.55	GO:0030425	dendrite
0.42	GO:0005615	extracellular space
0.36	GO:0009986	cell surface
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P28518|XPA_DROME
DNA repair protein complementing XP-A cells homolog
Search

XPA

0.78	DNA repair protein complementing XP-A cells

0.73	GO:0006289	nucleotide-excision repair
0.45	GO:0009411	response to UV
0.42	GO:0071482	cellular response to light stimulus
0.41	GO:0036297	interstrand cross-link repair
0.40	GO:0006284	base-excision repair
0.39	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.39	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.39	GO:0035264	multicellular organism growth
0.39	GO:0034504	protein localization to nucleus
0.38	GO:0051276	chromosome organization

0.73	GO:0003684	damaged DNA binding
0.38	GO:0019904	protein domain specific binding
0.38	GO:0042803	protein homodimerization activity
0.34	GO:0003690	double-stranded DNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003779	actin binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.61	GO:0005634	nucleus
0.40	GO:1990391	DNA repair complex
0.40	GO:0045171	intercellular bridge
0.39	GO:0043234	protein complex
0.38	GO:0030894	replisome
0.38	GO:0031974	membrane-enclosed lumen
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0044430	cytoskeletal part
0.30	GO:0031224	intrinsic component of membrane

sp|P28668|SYEP_DROME
Bifunctional glutamate/proline--tRNA ligase
Search

0.52	Bifunctional aminoacyl-trna synthetase

0.77	GO:0006433	prolyl-tRNA aminoacylation
0.72	GO:0006424	glutamyl-tRNA aminoacylation
0.38	GO:0051276	chromosome organization
0.38	GO:0071346	cellular response to interferon-gamma
0.36	GO:0017148	negative regulation of translation
0.33	GO:0007165	signal transduction
0.32	GO:0006351	transcription, DNA-templated

0.77	GO:0004827	proline-tRNA ligase activity
0.73	GO:0004818	glutamate-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0035613	RNA stem-loop binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0051020	GTPase binding
0.35	GO:0008270	zinc ion binding
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.49	GO:0005737	cytoplasm
0.43	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.38	GO:0097452	GAIT complex
0.38	GO:0005694	chromosome
0.34	GO:0030529	intracellular ribonucleoprotein complex

0.77

EC:6.1.1.15

GO:0004827

sp|P28750|EXU_DROME
Maternal protein exuperantia
Search

0.44	Maternal protein exuperantia

0.86	GO:0045450	bicoid mRNA localization
0.61	GO:0007317	regulation of pole plasm oskar mRNA localization
0.42	GO:0045451	pole plasm oskar mRNA localization
0.42	GO:0007300	ovarian nurse cell to oocyte transport
0.41	GO:0001700	embryonic development via the syncytial blastoderm
0.40	GO:0007283	spermatogenesis
0.39	GO:0000398	mRNA splicing, via spliceosome

0.75	GO:0042803	protein homodimerization activity
0.59	GO:0003723	RNA binding
0.38	GO:0004527	exonuclease activity

0.56	GO:0000932	P-body
0.41	GO:0071011	precatalytic spliceosome

sp|P29052|TF2B_DROME
Transcription initiation factor IIB
Search

0.53	Transcription initiation factor tFIIB

0.81	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.60	GO:0006413	translational initiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0051101	regulation of DNA binding
0.47	GO:0006367	transcription initiation from RNA polymerase II promoter
0.46	GO:0001173	DNA-templated transcriptional start site selection
0.42	GO:0051099	positive regulation of binding
0.41	GO:0050434	positive regulation of viral transcription

0.82	GO:0017025	TBP-class protein binding
0.61	GO:0003743	translation initiation factor activity
0.53	GO:0046872	metal ion binding
0.43	GO:0046966	thyroid hormone receptor binding
0.42	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding

0.44	GO:0097550	transcriptional preinitiation complex
0.41	GO:0005634	nucleus
0.40	GO:0000428	DNA-directed RNA polymerase complex
0.40	GO:0005667	transcription factor complex
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0000145	exocyst
0.30	GO:0016020	membrane

sp|P29310|1433Z_DROME
14-3-3 protein zeta
Search

0.87	Multifunctional chaperone

0.35	GO:0008103	oocyte microtubule cytoskeleton polarization
0.35	GO:0045448	mitotic cell cycle, embryonic
0.35	GO:0007294	germarium-derived oocyte fate determination
0.35	GO:0040040	thermosensory behavior
0.35	GO:0008355	olfactory learning
0.35	GO:0046579	positive regulation of Ras protein signal transduction
0.34	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.34	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.34	GO:0050821	protein stabilization
0.34	GO:0007399	nervous system development

0.77	GO:0019904	protein domain specific binding
0.35	GO:0008426	protein kinase C inhibitor activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0016301	kinase activity

0.35	GO:0045172	germline ring canal
0.34	GO:0005769	early endosome
0.34	GO:0031965	nuclear membrane
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane

sp|P29327|RS6_DROME
40S ribosomal protein S6
Search

RPS6

0.67	Ribosomal protein 6 (Fragment)

0.60	GO:0006518	peptide metabolic process
0.60	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0002309	T cell proliferation involved in immune response
0.50	GO:0022605	oogenesis stage
0.50	GO:0006924	activation-induced cell death of T cells
0.48	GO:0048821	erythrocyte development

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0019901	protein kinase binding
0.35	GO:0003676	nucleic acid binding

0.61	GO:0005840	ribosome
0.48	GO:0030425	dendrite
0.47	GO:0005844	polysome
0.46	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0044445	cytosolic part
0.45	GO:0044297	cell body
0.45	GO:0036464	cytoplasmic ribonucleoprotein granule
0.43	GO:0005730	nucleolus
0.42	GO:0005783	endoplasmic reticulum
0.35	GO:0000786	nucleosome

sp|P29349|CSW_DROME
Tyrosine-protein phosphatase corkscrew
Search

CSW

0.40	Tyrosine-protein phosphatase non-receptor type

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.43	GO:0007362	terminal region determination
0.43	GO:0008293	torso signaling pathway
0.40	GO:0045500	sevenless signaling pathway
0.40	GO:0007428	primary branching, open tracheal system
0.39	GO:0045314	regulation of compound eye photoreceptor development
0.39	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.39	GO:0007418	ventral midline development
0.39	GO:0007427	epithelial cell migration, open tracheal system
0.39	GO:0006911	phagocytosis, engulfment

0.73	GO:0004725	protein tyrosine phosphatase activity
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0005515	protein binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0016740	transferase activity
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005737	cytoplasm
0.33	GO:0043005	neuron projection
0.30	GO:0016020	membrane

0.73

GO:0004725

sp|P29413|CALR_DROME
Calreticulin
Search

0.78	Calreticulin

0.69	GO:0006457	protein folding
0.39	GO:0030431	sleep
0.39	GO:0042048	olfactory behavior
0.38	GO:0007417	central nervous system development
0.32	GO:0007422	peripheral nervous system development

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.34	GO:0030246	carbohydrate binding

0.70	GO:0005783	endoplasmic reticulum
0.39	GO:0045169	fusome
0.37	GO:0005615	extracellular space
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P29503|NEUR_DROME
Protein neuralized
Search

0.86	GO:0016360	sensory organ precursor cell fate determination
0.85	GO:0045614	negative regulation of plasmatocyte differentiation
0.85	GO:0035203	regulation of lamellocyte differentiation
0.84	GO:0045314	regulation of compound eye photoreceptor development
0.82	GO:0007422	peripheral nervous system development
0.81	GO:0007498	mesoderm development
0.80	GO:0030718	germ-line stem cell population maintenance
0.79	GO:0007616	long-term memory
0.79	GO:0048581	negative regulation of post-embryonic development
0.78	GO:0008356	asymmetric cell division

0.73	GO:1901981	phosphatidylinositol phosphate binding
0.71	GO:0004842	ubiquitin-protein transferase activity
0.70	GO:0061659	ubiquitin-like protein ligase activity
0.45	GO:0008270	zinc ion binding
0.45	GO:0003677	DNA binding
0.45	GO:0005515	protein binding
0.40	GO:0016874	ligase activity

0.73	GO:0048471	perinuclear region of cytoplasm
0.69	GO:0005768	endosome
0.54	GO:0005886	plasma membrane
0.49	GO:0005634	nucleus
0.47	GO:0005829	cytosol

0.40	EC:6	GO:0016874
0.71	KEGG:R03876	GO:0004842

sp|P29555|ABDA_DROME
Homeobox protein abdominal-A
Search

ABD-A

0.89	Homeobox protein abdominal-A

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0035053	dorsal vessel heart proper cell fate commitment
0.51	GO:0007438	oenocyte development
0.51	GO:0035224	genital disc anterior/posterior pattern formation
0.51	GO:0035225	determination of genital disc primordium
0.51	GO:0007506	gonadal mesoderm development
0.51	GO:0042694	muscle cell fate specification
0.50	GO:0014019	neuroblast development

0.64	GO:0043565	sequence-specific DNA binding
0.48	GO:0033613	activating transcription factor binding
0.48	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex

0.33

EC:2.4.2.30

GO:0003950

sp|P29613|TPIS_DROME
Triosephosphate isomerase
Search

TPI

0.47	Triosephosphate isomerase

0.73	GO:0019319	hexose biosynthetic process
0.72	GO:0006098	pentose-phosphate shunt
0.71	GO:0006006	glucose metabolic process
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.38	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.36	GO:0046174	polyol catabolic process
0.36	GO:0006071	glycerol metabolic process
0.35	GO:0007525	somatic muscle development

0.78	GO:0004807	triose-phosphate isomerase activity
0.34	GO:0042803	protein homodimerization activity
0.32	GO:0046872	metal ion binding

0.35	GO:0031430	M band
0.35	GO:0030018	Z disc
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78	EC:5.3.1.1	GO:0004807
0.78	KEGG:R01015	GO:0004807

sp|P29615|LYSP_DROME
Lysozyme P
Search

0.53	Lysozyme P

0.42	GO:0050830	defense response to Gram-positive bacterium
0.42	GO:0050829	defense response to Gram-negative bacterium
0.41	GO:0019835	cytolysis
0.41	GO:0016998	cell wall macromolecule catabolic process
0.34	GO:0045824	negative regulation of innate immune response

0.77	GO:0003796	lysozyme activity
0.34	GO:0004568	chitinase activity

0.40	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0003796

sp|P29617|PROS_DROME
Homeobox protein prospero
Search

0.75	Homeobox protein prospero

0.45	GO:0055060	asymmetric neuroblast division resulting in ganglion mother cell formation
0.44	GO:0042673	regulation of retinal cone cell fate specification
0.44	GO:0042676	compound eye cone cell fate commitment
0.44	GO:0007402	ganglion mother cell fate determination
0.44	GO:0007465	R7 cell fate commitment
0.43	GO:0060385	axonogenesis involved in innervation
0.43	GO:0070314	G1 to G0 transition
0.43	GO:0045676	regulation of R7 cell differentiation
0.43	GO:0007400	neuroblast fate determination
0.43	GO:0070983	dendrite guidance

0.55	GO:0003677	DNA binding
0.43	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.43	GO:0045180	basal cortex
0.43	GO:0045179	apical cortex
0.38	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane

sp|P29673|APTE_DROME
Protein apterous
Search

LHX2

0.86	Bmptp-Z and Bmap-A fusion protein alpha

0.61	GO:0007481	haltere disc morphogenesis
0.59	GO:0007479	leg disc proximal/distal pattern formation
0.59	GO:0007482	haltere development
0.58	GO:0036011	imaginal disc-derived leg segmentation
0.58	GO:0007526	larval somatic muscle development
0.57	GO:0048190	wing disc dorsal/ventral pattern formation
0.57	GO:0060033	anatomical structure regression
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0046872	metal ion binding
0.51	GO:0003690	double-stranded DNA binding
0.39	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.38	GO:0003682	chromatin binding
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0003714	transcription corepressor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0004725

sp|P29681|IMPE2_DROME
20-hydroxyecdysone protein
Search

IMPE2

0.97	20-hydroxyecdysone protein (Fragment)

0.52	GO:0007561	imaginal disc eversion
0.38	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.36	GO:0006413	translational initiation
0.35	GO:0065007	biological regulation
0.34	GO:0000226	microtubule cytoskeleton organization
0.34	GO:0023052	signaling
0.34	GO:0007154	cell communication
0.34	GO:0051716	cellular response to stimulus
0.34	GO:0018106	peptidyl-histidine phosphorylation
0.34	GO:0006508	proteolysis

0.39	GO:0003924	GTPase activity
0.39	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.37	GO:0003743	translation initiation factor activity
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0042834	peptidoglycan binding

0.64	GO:0005576	extracellular region
0.48	GO:0005737	cytoplasm
0.46	GO:0019898	extrinsic component of membrane
0.37	GO:0031226	intrinsic component of plasma membrane
0.35	GO:1990913	sperm head plasma membrane
0.35	GO:0005856	cytoskeleton
0.34	GO:0016592	mediator complex
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0099512	supramolecular fiber
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.35

GO:0004222

sp|P29742|CLH_DROME
Clathrin heavy chain
Search

0.66	Clathrin heavy chain

0.83	GO:0048268	clathrin coat assembly
0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.46	GO:0007594	puparial adhesion
0.46	GO:0046667	compound eye retinal cell programmed cell death
0.45	GO:2000366	positive regulation of STAT protein import into nucleus
0.45	GO:0035002	liquid clearance, open tracheal system
0.45	GO:0008103	oocyte microtubule cytoskeleton polarization
0.44	GO:0045451	pole plasm oskar mRNA localization
0.44	GO:0035159	regulation of tube length, open tracheal system

0.85	GO:0032051	clathrin light chain binding
0.61	GO:0005198	structural molecule activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0071439	clathrin complex
0.82	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.81	GO:0030132	clathrin coat of coated pit
0.42	GO:0005802	trans-Golgi network
0.42	GO:0030141	secretory granule
0.42	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0098793	presynapse
0.41	GO:0019028	viral capsid
0.41	GO:0005938	cell cortex
0.35	GO:0005819	spindle

sp|P29746|BNB_DROME
Protein bangles and beads
Search

BNB

0.97	Bangles and beads protein (Fragment)

0.78	GO:0042063	gliogenesis
0.37	GO:0018106	peptidyl-histidine phosphorylation
0.37	GO:0006935	chemotaxis
0.36	GO:0023014	signal transduction by protein phosphorylation
0.36	GO:0072594	establishment of protein localization to organelle
0.36	GO:0000160	phosphorelay signal transduction system
0.35	GO:0006613	cotranslational protein targeting to membrane
0.35	GO:0070972	protein localization to endoplasmic reticulum
0.35	GO:0016570	histone modification
0.35	GO:0051301	cell division

0.36	GO:0000155	phosphorelay sensor kinase activity
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003924	GTPase activity
0.35	GO:0008144	drug binding
0.34	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.34	GO:0008939	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
0.34	GO:0003723	RNA binding
0.34	GO:0004842	ubiquitin-protein transferase activity

0.35	GO:0044459	plasma membrane part
0.34	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.33	GO:0098562	cytoplasmic side of membrane
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0044165	host cell endoplasmic reticulum
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0033644	host cell membrane
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

0.36	EC:2.7.3	GO:0000155
0.34	KEGG:R04148	GO:0008939

sp|P29747|CREBA_DROME
Cyclic AMP response element-binding protein A
Search

0.78	Cyclic AMP response element-binding protein A

0.59	GO:0035293	chitin-based larval cuticle pattern formation
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0007431	salivary gland development
0.55	GO:0009953	dorsal/ventral pattern formation
0.52	GO:0030968	endoplasmic reticulum unfolded protein response
0.40	GO:0042981	regulation of apoptotic process
0.38	GO:0022612	gland morphogenesis
0.37	GO:0002062	chondrocyte differentiation
0.36	GO:0006888	ER to Golgi vesicle-mediated transport
0.36	GO:0006351	transcription, DNA-templated

0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.56	GO:0035326	enhancer binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0042803	protein homodimerization activity
0.33	GO:0003697	single-stranded DNA binding

0.56	GO:0005700	polytene chromosome
0.53	GO:0005634	nucleus
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0031224	intrinsic component of membrane

sp|P29774|ETS3_DROME
DNA-binding protein D-ETS-3
Search

0.76	DNA-binding protein D-ETS-3

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0030154	cell differentiation
0.41	GO:0001525	angiogenesis
0.36	GO:0030097	hemopoiesis
0.35	GO:0042742	defense response to bacterium
0.34	GO:0060348	bone development
0.34	GO:0008015	blood circulation
0.34	GO:0006468	protein phosphorylation

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0003682	chromatin binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0005840	ribosome
0.32	GO:0044446	intracellular organelle part

0.33

GO:0016758

sp|P29775|ETS4_DROME
DNA-binding protein D-ETS-4
Search

0.76	DNA-binding protein D-ETS-4

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0060480	lung goblet cell differentiation
0.47	GO:0060576	intestinal epithelial cell development
0.47	GO:0010455	positive regulation of cell fate commitment
0.47	GO:0010454	negative regulation of cell fate commitment
0.45	GO:0043065	positive regulation of apoptotic process
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:1902679	negative regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

sp|P29776|ETS6_DROME
DNA-binding protein D-ETS-6
Search

0.91	DNA-binding protein D-ETS-6

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0042742	defense response to bacterium
0.43	GO:0032502	developmental process
0.42	GO:0032501	multicellular organismal process
0.40	GO:0048518	positive regulation of biological process
0.39	GO:0002376	immune system process
0.38	GO:0044093	positive regulation of molecular function
0.37	GO:0006366	transcription by RNA polymerase II

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.40	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.37	GO:0003682	chromatin binding
0.35	GO:0005230	extracellular ligand-gated ion channel activity
0.35	GO:0004888	transmembrane signaling receptor activity

0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P29829|GBB2_DROME
Guanine nucleotide-binding protein subunit beta-2
Search

0.83	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.49	GO:0016059	deactivation of rhodopsin mediated signaling
0.48	GO:0007202	activation of phospholipase C activity
0.45	GO:0071482	cellular response to light stimulus
0.45	GO:0009584	detection of visible light
0.35	GO:0032501	multicellular organismal process
0.34	GO:0006413	translational initiation
0.34	GO:0071377	cellular response to glucagon stimulus
0.34	GO:0016573	histone acetylation
0.34	GO:0006928	movement of cell or subcellular component

0.43	GO:0005515	protein binding
0.35	GO:0004871	signal transducer activity
0.34	GO:0003743	translation initiation factor activity
0.34	GO:0004402	histone acetyltransferase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0044877	macromolecular complex binding

0.48	GO:0016028	rhabdomere
0.45	GO:1905360	GTPase complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0030425	dendrite
0.41	GO:0098797	plasma membrane protein complex
0.36	GO:0005737	cytoplasm
0.34	GO:0030286	dynein complex
0.33	GO:0070062	extracellular exosome
0.33	GO:0044297	cell body
0.30	GO:0016021	integral component of membrane

0.34

GO:0004402

sp|P29843|HSP7A_DROME
Heat shock 70 kDa protein cognate 1
Search

0.61	Heat shock protein cognate 1

0.43	GO:0061738	late endosomal microautophagy
0.42	GO:0070868	heterochromatin organization involved in chromatin silencing
0.42	GO:0007413	axonal fasciculation
0.42	GO:0001700	embryonic development via the syncytial blastoderm
0.42	GO:0016246	RNA interference
0.41	GO:0030707	ovarian follicle cell development
0.41	GO:0099643	signal release from synapse
0.41	GO:0035967	cellular response to topologically incorrect protein
0.41	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.41	GO:0007411	axon guidance

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0051087	chaperone binding
0.38	GO:0004672	protein kinase activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0051082	unfolded protein binding

0.43	GO:0005726	perichromatin fibrils
0.41	GO:0030018	Z disc
0.40	GO:0098793	presynapse
0.37	GO:0005739	mitochondrion
0.37	GO:0019866	organelle inner membrane
0.34	GO:0071011	precatalytic spliceosome
0.34	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0032440

sp|P29844|HSP7C_DROME
Heat shock 70 kDa protein cognate 3
Search

0.40	Delta-aminolevulinic acid dehydratase

0.46	GO:0036335	intestinal stem cell homeostasis
0.44	GO:0016246	RNA interference
0.43	GO:0034976	response to endoplasmic reticulum stress
0.35	GO:0030431	sleep
0.35	GO:0006779	porphyrin-containing compound biosynthetic process
0.33	GO:0006457	protein folding
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004655	porphobilinogen synthase activity
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.41	GO:0005615	extracellular space
0.41	GO:0005783	endoplasmic reticulum
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.37	EC:4.2.1.24	GO:0004655
0.37	KEGG:R00036	GO:0004655

sp|P29845|HSP7E_DROME
Heat shock 70 kDa protein cognate 5
Search

0.46	Molecular chaperone DnaK

0.68	GO:0006457	protein folding
0.47	GO:0010918	positive regulation of mitochondrial membrane potential
0.46	GO:0070584	mitochondrion morphogenesis
0.45	GO:0000422	autophagy of mitochondrion
0.39	GO:0030097	hemopoiesis
0.39	GO:0031101	fin regeneration
0.37	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.37	GO:0045647	negative regulation of erythrocyte differentiation
0.36	GO:0006611	protein export from nucleus
0.36	GO:0034101	erythrocyte homeostasis

0.70	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0016887	ATPase activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.38	GO:0005759	mitochondrial matrix
0.36	GO:0043209	myelin sheath
0.35	GO:0009295	nucleoid
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.35

GO:0016887

sp|P29993|ITPR_DROME
Inositol 1,4,5-trisphosphate receptor
Search

0.77	Inositol 1,4,5-trisphosphate receptor type 1

0.83	GO:0048016	inositol phosphate-mediated signaling
0.77	GO:0006816	calcium ion transport
0.61	GO:0098662	inorganic cation transmembrane transport
0.53	GO:0046000	positive regulation of ecdysteroid secretion
0.50	GO:0030536	larval feeding behavior
0.50	GO:0007629	flight behavior
0.50	GO:0035071	salivary gland cell autophagic cell death
0.50	GO:0055089	fatty acid homeostasis
0.50	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.49	GO:0030322	stabilization of membrane potential

0.84	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.83	GO:0070679	inositol 1,4,5 trisphosphate binding
0.37	GO:0005509	calcium ion binding

0.68	GO:0005783	endoplasmic reticulum
0.49	GO:0044295	axonal growth cone
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P30052|SCAL_DROME
Protein scalloped
Search

0.71	Transcriptional enhancer factor

0.81	GO:0035329	hippo signaling
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.40	GO:0048568	embryonic organ development
0.39	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0035331	negative regulation of hippo signaling
0.36	GO:0007480	imaginal disc-derived leg morphogenesis
0.36	GO:0007525	somatic muscle development

0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003677	DNA binding
0.40	GO:0001085	RNA polymerase II transcription factor binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0019904	protein domain specific binding
0.33	GO:0001223	transcription coactivator binding
0.33	GO:0046872	metal ion binding
0.33	GO:0001134	transcription factor activity, transcription factor recruiting
0.32	GO:0046982	protein heterodimerization activity

0.55	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P30189|TOP1_DROME
DNA topoisomerase 1
Search

TOP1

0.39	Eukaryotic DNA topoisomerase I

0.72	GO:0006265	DNA topological change
0.34	GO:0006338	chromatin remodeling
0.34	GO:0007059	chromosome segregation
0.33	GO:0006260	DNA replication
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0002168	instar larval development
0.32	GO:0045995	regulation of embryonic development
0.32	GO:0048477	oogenesis
0.32	GO:0008283	cell proliferation
0.32	GO:0030261	chromosome condensation

0.77	GO:0003917	DNA topoisomerase type I activity
0.55	GO:0003677	DNA binding
0.42	GO:0061505	DNA topoisomerase II activity
0.41	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0008270	zinc ion binding

0.68	GO:0005694	chromosome
0.36	GO:0042645	mitochondrial nucleoid
0.35	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.32	GO:0000428	DNA-directed RNA polymerase complex
0.31	GO:0005829	cytosol

0.77

EC:5.99.1.2

GO:0003917

sp|P30432|FUR2_DROME
Furin-like protease 2
Search

FUR2

0.96	Furin protease

0.60	GO:0006508	proteolysis
0.30	GO:0051051	negative regulation of transport
0.30	GO:0051046	regulation of secretion

0.68

GO:0004252

serine-type endopeptidase activity

0.40	GO:0005604	basement membrane
0.30	GO:0071944	cell periphery
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004252

sp|P30974|TLR1_DROME
Tachykinin-like peptides receptor 86C
Search

0.77	Class a rhodopsin g-protein coupled receptor gprllk

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0002121	inter-male aggressive behavior
0.33	GO:0006468	protein phosphorylation

0.77	GO:0008188	neuropeptide receptor activity
0.35	GO:0050254	rhodopsin kinase activity

0.45	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.35

EC:2.7.11.14

GO:0050254

sp|P30975|TLR2_DROME
Tachykinin-like peptides receptor 99D
Search

0.56	G protein-coupled receptor

0.83	GO:0007217	tachykinin receptor signaling pathway
0.46	GO:0007218	neuropeptide signaling pathway
0.38	GO:1904058	positive regulation of sensory perception of pain
0.37	GO:0050804	modulation of chemical synaptic transmission
0.37	GO:0042048	olfactory behavior
0.36	GO:0007600	sensory perception
0.36	GO:0009593	detection of chemical stimulus
0.36	GO:0023057	negative regulation of signaling
0.36	GO:0010648	negative regulation of cell communication
0.35	GO:0046878	positive regulation of saliva secretion

0.84	GO:0004995	tachykinin receptor activity
0.44	GO:0004983	neuropeptide Y receptor activity
0.36	GO:0050254	rhodopsin kinase activity

0.54	GO:0005886	plasma membrane
0.34	GO:0061827	sperm head
0.34	GO:0097225	sperm midpiece
0.34	GO:0030425	dendrite
0.34	GO:0044297	cell body
0.33	GO:0009986	cell surface
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.36

EC:2.7.11.14

GO:0050254

sp|P31007|DLG1_DROME
Disks large 1 tumor suppressor protein
Search

LOC108091061

0.75	Putative calcium/calmodulin-dependent serine protein kinase/membrane-associated guanylate kinase

0.57	GO:0030710	regulation of border follicle cell delamination
0.57	GO:0030714	anterior/posterior axis specification, follicular epithelium
0.55	GO:0016336	establishment or maintenance of polarity of larval imaginal disc epithelium
0.55	GO:0006796	phosphate-containing compound metabolic process
0.55	GO:0016332	establishment or maintenance of polarity of embryonic epithelium
0.54	GO:0046956	positive phototaxis
0.54	GO:0045175	basal protein localization
0.54	GO:0007318	pole plasm protein localization
0.53	GO:0045196	establishment or maintenance of neuroblast polarity
0.53	GO:0045167	asymmetric protein localization involved in cell fate determination

0.60	GO:0016301	kinase activity
0.53	GO:0035255	ionotropic glutamate receptor binding
0.52	GO:0005154	epidermal growth factor receptor binding
0.50	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.43	GO:0004871	signal transducer activity
0.42	GO:0005198	structural molecule activity

0.54	GO:0005920	smooth septate junction
0.54	GO:0061176	type Ib terminal bouton
0.54	GO:0071212	subsynaptic reticulum
0.53	GO:0061689	tricellular tight junction
0.52	GO:0016327	apicolateral plasma membrane
0.52	GO:0045179	apical cortex
0.51	GO:0042734	presynaptic membrane
0.51	GO:0008328	ionotropic glutamate receptor complex
0.51	GO:0016328	lateral plasma membrane
0.51	GO:0031594	neuromuscular junction

0.50

EC:2.7.4

GO:0016776

sp|P31009|RS2_DROME
40S ribosomal protein S2
Search

0.56	Ribosomal protein S5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0007275	multicellular organism development
0.34	GO:0048477	oogenesis

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding

0.70	GO:0015935	small ribosomal subunit
0.40	GO:0000228	nuclear chromosome
0.40	GO:0005730	nucleolus
0.37	GO:0022626	cytosolic ribosome

sp|P31264|HMPB_DROME
Homeotic protein proboscipedia
Search

0.92	Homeotic protein proboscipedia

0.65	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0060322	head development
0.44	GO:0060429	epithelium development

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

GO:0004000

sp|P31368|PDM1_DROME
Protein nubbin
Search

0.44	POU domain protein (Fragment)

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0048863	stem cell differentiation
0.42	GO:0007398	ectoderm development
0.42	GO:0007417	central nervous system development
0.41	GO:0048699	generation of neurons
0.41	GO:0048468	cell development
0.41	GO:0051254	positive regulation of RNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|P31396|HR3_DROME
Probable nuclear hormone receptor HR3
Search

HR3

0.92	Molt-regulating transcription factor HaHR3

0.76	GO:0043401	steroid hormone mediated signaling pathway
0.75	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0016319	mushroom body development
0.36	GO:0040034	regulation of development, heterochronic
0.36	GO:0007552	metamorphosis
0.35	GO:0051254	positive regulation of RNA metabolic process

0.81	GO:0004887	thyroid hormone receptor activity
0.77	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P31409|VATB_DROME
V-type proton ATPase subunit B
Search

0.70	ATP synthase subunit beta vacuolar

0.74	GO:0015991	ATP hydrolysis coupled proton transport
0.61	GO:0046034	ATP metabolic process
0.42	GO:0007035	vacuolar acidification

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0036442	proton-exporting ATPase activity
0.39	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.38	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

0.79	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.43	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.42	GO:0005903	brush border
0.41	GO:0005769	early endosome
0.41	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.33	GO:0005829	cytosol

sp|P32027|CROC_DROME
Fork head domain-containing protein crocodile
Search

0.73	Fork head domain-containing protein crocodile

0.59	GO:0007380	specification of segmental identity, head
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0072010	glomerular epithelium development
0.46	GO:0014032	neural crest cell development
0.46	GO:0001756	somitogenesis
0.45	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis
0.45	GO:0003018	vascular process in circulatory system
0.45	GO:0043010	camera-type eye development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.43	GO:1990841	promoter-specific chromatin binding
0.43	GO:0001223	transcription coactivator binding
0.41	GO:0044212	transcription regulatory region DNA binding
0.41	GO:0008301	DNA binding, bending
0.40	GO:0003713	transcription coactivator activity
0.38	GO:0003690	double-stranded DNA binding
0.36	GO:0031490	chromatin DNA binding
0.35	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.40	GO:0000792	heterochromatin
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P32028|FD4_DROME
Fork head domain-containing protein FD4
Search

0.79	Winged helix transcription factor Forkhead-1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0061381	cell migration in diencephalon
0.49	GO:0061374	mammillothalamic axonal tract development
0.49	GO:0061379	inferior colliculus development
0.48	GO:0021855	hypothalamus cell migration
0.48	GO:0007412	axon target recognition
0.48	GO:0033504	floor plate development
0.47	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P32029|FD5_DROME
Fork head domain-containing protein FD5
Search

0.71	Fork head domain-containing protein FD5

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0061381	cell migration in diencephalon
0.51	GO:0061374	mammillothalamic axonal tract development
0.50	GO:0061379	inferior colliculus development
0.49	GO:0021855	hypothalamus cell migration
0.49	GO:0007412	axon target recognition
0.49	GO:0033504	floor plate development
0.48	GO:0008542	visual learning

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P32030|SLP1_DROME
Fork head domain transcription factor slp1
Search

0.87	Fork head domain transcription factor slp1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0007380	specification of segmental identity, head
0.48	GO:0060914	heart formation
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0030154	cell differentiation
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:0007365	periodic partitioning
0.37	GO:0007351	tripartite regional subdivision

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.47	GO:0035326	enhancer binding
0.43	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0042025	host cell nucleus

sp|P32031|SLP2_DROME
Fork head domain transcription factor slp2
Search

0.82	Transforming protein Qin

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0030154	cell differentiation
0.43	GO:0009653	anatomical structure morphogenesis
0.42	GO:0043584	nose development
0.41	GO:0009790	embryo development
0.41	GO:0060041	retina development in camera-type eye
0.40	GO:0006351	transcription, DNA-templated
0.40	GO:0007399	nervous system development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003779	actin binding

0.61	GO:0005634	nucleus
0.34	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P32100|RL7_DROME
60S ribosomal protein L7
Search

0.67	Ribosomal protein L7 isoform A

0.49	GO:0035073	pupariation
0.39	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.39	GO:0002181	cytoplasmic translation
0.34	GO:0007076	mitotic chromosome condensation
0.34	GO:0051726	regulation of cell cycle

0.36	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding

0.59	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part
0.34	GO:0000793	condensed chromosome
0.34	GO:0044815	DNA packaging complex
0.33	GO:0043234	protein complex

sp|P32234|128UP_DROME
GTP-binding protein 128up
Search

128UP

0.41	Developmentally-regulated GTP-binding protein 1

0.66	GO:0001883	purine nucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0042802	identical protein binding

0.40	GO:0005844	polysome
0.39	GO:0016604	nuclear body
0.37	GO:0005829	cytosol

sp|P32392|ARP3_DROME
Actin-related protein 3
Search

0.52

Actin

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.47	GO:0030589	pseudocleavage involved in syncytial blastoderm formation
0.47	GO:0030713	ovarian follicle cell stalk formation
0.47	GO:0030037	actin filament reorganization involved in cell cycle
0.47	GO:0072553	terminal button organization
0.47	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.46	GO:0010592	positive regulation of lamellipodium assembly
0.46	GO:0022416	chaeta development
0.46	GO:0007413	axonal fasciculation
0.46	GO:0051491	positive regulation of filopodium assembly

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003779	actin binding
0.38	GO:0005200	structural constituent of cytoskeleton
0.37	GO:0032403	protein complex binding

0.80	GO:0005885	Arp2/3 protein complex
0.46	GO:0030027	lamellipodium
0.37	GO:0005903	brush border
0.36	GO:0005911	cell-cell junction
0.34	GO:0005884	actin filament
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P32748|PYRD_DROME
Dihydroorotate dehydrogenase (quinone), mitochondrial
Search

0.79	Dihydroorotate dehydrogenase (quinone), mitochondrial

0.74	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.71	GO:0006222	UMP biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0000390	spliceosomal complex disassembly
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0000278	mitotic cell cycle
0.33	GO:0006869	lipid transport
0.32	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway
0.32	GO:0006508	proteolysis

0.79	GO:0004152	dihydroorotate dehydrogenase activity
0.34	GO:0005549	odorant binding
0.34	GO:0005319	lipid transporter activity
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0004163	diphosphomevalonate decarboxylase activity
0.32	GO:0004252	serine-type endopeptidase activity

0.58	GO:0031966	mitochondrial membrane
0.58	GO:0019866	organelle inner membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.37	GO:0005886	plasma membrane
0.35	GO:0044428	nuclear part
0.34	GO:0005829	cytosol
0.34	GO:0000775	chromosome, centromeric region
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.79	EC:1.3.5.2	GO:0004152
0.79	KEGG:R01868	GO:0004152

sp|P32845|NULLO_DROME
Protein nullo
Search

0.87	GO:0036089	cleavage furrow formation
0.84	GO:0007043	cell-cell junction assembly
0.83	GO:0016331	morphogenesis of embryonic epithelium
0.69	GO:0008360	regulation of cell shape
0.51	GO:0007349	cellularization
0.50	GO:0044837	actomyosin contractile ring organization
0.50	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.43	GO:0008104	protein localization

0.46

GO:0003779

actin binding

0.48	GO:0005912	adherens junction
0.47	GO:0005911	cell-cell junction

sp|P32865|GPRK1_DROME
G protein-coupled receptor kinase 1
Search

0.70	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0007165	signal transduction
0.51	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.50	GO:0003108	negative regulation of the force of heart contraction by chemical signal
0.48	GO:0045988	negative regulation of striated muscle contraction
0.48	GO:0022401	negative adaptation of signaling pathway
0.48	GO:0048513	animal organ development
0.47	GO:0031623	receptor internalization
0.47	GO:0060048	cardiac muscle contraction
0.46	GO:0018210	peptidyl-threonine modification

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.45	GO:0050254	rhodopsin kinase activity
0.41	GO:0035091	phosphatidylinositol binding
0.41	GO:0047696	beta-adrenergic receptor kinase activity
0.37	GO:0031694	alpha-2A adrenergic receptor binding
0.34	GO:0016868	intramolecular transferase activity, phosphotransferases

0.36	GO:0005737	cytoplasm
0.36	GO:0120025	plasma membrane bounded cell projection
0.35	GO:0005886	plasma membrane
0.34	GO:0098857	membrane microdomain
0.34	GO:0045177	apical part of cell
0.34	GO:0036477	somatodendritic compartment
0.34	GO:0098794	postsynapse
0.33	GO:0044463	cell projection part
0.33	GO:0043226	organelle

0.85

EC:2.7.11.16

GO:0004703

sp|P32866|GPRK2_DROME
G protein-coupled receptor kinase 2
Search

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0007165	signal transduction
0.52	GO:0048601	oocyte morphogenesis
0.51	GO:0003384	apical constriction involved in gastrulation
0.50	GO:0008592	regulation of Toll signaling pathway
0.50	GO:0043950	positive regulation of cAMP-mediated signaling
0.50	GO:0002805	regulation of antimicrobial peptide biosynthetic process
0.50	GO:0007474	imaginal disc-derived wing vein specification
0.49	GO:0045879	negative regulation of smoothened signaling pathway
0.48	GO:0050830	defense response to Gram-positive bacterium

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0047696	beta-adrenergic receptor kinase activity
0.34	GO:0008289	lipid binding
0.34	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.34	GO:0005080	protein kinase C binding

0.44	GO:0016607	nuclear speck
0.44	GO:0031965	nuclear membrane
0.41	GO:0005886	plasma membrane
0.41	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.85

EC:2.7.11.16

GO:0004703

sp|P32870|CYA1_DROME
Ca(2+)/calmodulin-responsive adenylate cyclase
Search

RUT

0.60	Ca(2+)/calmodulin-responsive adenylate cyclase

0.77	GO:0006171	cAMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.60	GO:0090328	regulation of olfactory learning
0.60	GO:0007615	anesthesia-resistant memory
0.60	GO:0072375	medium-term memory
0.60	GO:0001661	conditioned taste aversion
0.58	GO:0007614	short-term memory
0.58	GO:0030431	sleep
0.57	GO:0048149	behavioral response to ethanol
0.57	GO:0007591	molting cycle, chitin-based cuticle

0.77	GO:0004016	adenylate cyclase activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.42	GO:0004383	guanylate cyclase activity
0.40	GO:0005516	calmodulin binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0046872	metal ion binding
0.35	GO:0043168	anion binding

0.54	GO:0005886	plasma membrane
0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.77

EC:4.6.1.1

GO:0004016

sp|P33085|SHAKB_DROME
Innexin shaking-B
Search

INX

0.66	Innexin shaking-B

0.59	GO:0006811	ion transport
0.40	GO:0016264	gap junction assembly
0.39	GO:0010496	intercellular transport
0.38	GO:0009416	response to light stimulus
0.37	GO:0007630	jump response
0.37	GO:0036098	male germ-line stem cell population maintenance
0.36	GO:0030727	germarium-derived female germ-line cyst formation
0.36	GO:0007440	foregut morphogenesis
0.36	GO:0010644	cell communication by electrical coupling
0.36	GO:0003254	regulation of membrane depolarization

0.41	GO:0005243	gap junction channel activity
0.38	GO:0009881	photoreceptor activity

0.81	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.35	GO:0045177	apical part of cell
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P33244|FTZF1_DROME
Nuclear hormone receptor FTZ-F1
Search

0.71	Nuclear hormone receptor FTZ-F1

0.76	GO:0043401	steroid hormone mediated signaling pathway
0.64	GO:0035074	pupation
0.64	GO:0035626	juvenile hormone mediated signaling pathway
0.63	GO:0035073	pupariation
0.61	GO:0007365	periodic partitioning
0.61	GO:0016322	neuron remodeling
0.61	GO:0016319	mushroom body development
0.61	GO:0007480	imaginal disc-derived leg morphogenesis
0.59	GO:0048813	dendrite morphogenesis
0.58	GO:0006351	transcription, DNA-templated

0.77	GO:0003707	steroid hormone receptor activity
0.61	GO:0043565	sequence-specific DNA binding
0.59	GO:0008270	zinc ion binding
0.58	GO:0003700	DNA binding transcription factor activity
0.55	GO:0044212	transcription regulatory region DNA binding
0.54	GO:0046982	protein heterodimerization activity
0.53	GO:0003690	double-stranded DNA binding
0.53	GO:0008134	transcription factor binding
0.41	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P33269|CP4D1_DROME
Cytochrome P450 4d1
Search

0.41	p450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0050830	defense response to Gram-positive bacterium
0.33	GO:0055085	transmembrane transport
0.32	GO:0061774	cohesin unloading
0.32	GO:0007062	sister chromatid cohesion
0.32	GO:0000278	mitotic cell cycle
0.32	GO:0006325	chromatin organization

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.34	GO:0043190	ATP-binding cassette (ABC) transporter complex
0.32	GO:0005700	polytene chromosome
0.31	GO:0005634	nucleus

0.68

GO:0016705

sp|P33270|CP6A2_DROME
Cytochrome P450 6a2
Search

0.10	Cytochrome P450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0017085	response to insecticide
0.50	GO:0031000	response to caffeine
0.41	GO:0048252	lauric acid metabolic process
0.38	GO:0006805	xenobiotic metabolic process
0.37	GO:0009404	toxin metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0009055	electron transfer activity

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P33438|GLT_DROME
Glutactin
Search

0.22	Carboxylesterase

0.80	GO:0016201	synaptic target inhibition
0.75	GO:0008045	motor neuron axon guidance
0.66	GO:0098542	defense response to other organism
0.53	GO:0097105	presynaptic membrane assembly
0.53	GO:0097104	postsynaptic membrane assembly
0.53	GO:0007158	neuron cell-cell adhesion
0.51	GO:0048488	synaptic vesicle endocytosis
0.49	GO:0050804	modulation of chemical synaptic transmission
0.40	GO:0006937	regulation of muscle contraction
0.38	GO:0000226	microtubule cytoskeleton organization

0.51	GO:0042043	neurexin family protein binding
0.45	GO:0052689	carboxylic ester hydrolase activity
0.43	GO:0004872	receptor activity
0.37	GO:0005509	calcium ion binding
0.36	GO:0005525	GTP binding
0.36	GO:0003924	GTPase activity
0.35	GO:0003743	translation initiation factor activity
0.35	GO:0046914	transition metal ion binding
0.34	GO:0003779	actin binding
0.34	GO:0140096	catalytic activity, acting on a protein

0.72	GO:0005604	basement membrane
0.47	GO:0009986	cell surface
0.47	GO:0045202	synapse
0.44	GO:0031226	intrinsic component of plasma membrane
0.41	GO:0005856	cytoskeleton
0.40	GO:0036379	myofilament
0.40	GO:0030017	sarcomere
0.37	GO:0044446	intracellular organelle part
0.37	GO:0005794	Golgi apparatus
0.36	GO:0043234	protein complex

0.45	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.45	KEGG:R00630	GO:0052689

sp|P33450|FAT_DROME
Cadherin-related tumor suppressor
Search

0.56	Cadherin-related tumor suppressor fat

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0016336	establishment or maintenance of polarity of larval imaginal disc epithelium
0.52	GO:0045317	equator specification
0.52	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.52	GO:0045571	negative regulation of imaginal disc growth
0.51	GO:0048105	establishment of body hair planar orientation
0.51	GO:0007446	imaginal disc growth
0.51	GO:0035209	pupal development
0.51	GO:0044331	cell-cell adhesion mediated by cadherin
0.51	GO:0001737	establishment of imaginal disc-derived wing hair orientation

0.69	GO:0005509	calcium ion binding
0.47	GO:0045296	cadherin binding
0.32	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.32	GO:0004022	alcohol dehydrogenase (NAD) activity
0.32	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.31	GO:0004693	cyclin-dependent protein serine/threonine kinase activity

0.55	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.30	GO:0045177	apical part of cell
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.32

EC:2.7.11.23

GO:0008353

sp|P34021|ECR_DROME
Ecdysone receptor
Search

ECR

0.74	Ecdysone receptor

0.86	GO:0035076	ecdysone receptor-mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0035053	dorsal vessel heart proper cell fate commitment
0.53	GO:0035180	larval wandering behavior
0.52	GO:0035193	larval central nervous system remodeling
0.52	GO:0035297	regulation of Malpighian tubule diameter
0.52	GO:1904799	regulation of neuron remodeling

0.86	GO:0004884	ecdysteroid hormone receptor activity
0.82	GO:0005496	steroid binding
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.52	GO:0001225	RNA polymerase II transcription coactivator binding
0.49	GO:0070491	repressing transcription factor binding
0.49	GO:0042562	hormone binding
0.48	GO:0001047	core promoter binding
0.48	GO:0043178	alcohol binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.49	GO:0005700	polytene chromosome
0.47	GO:0030425	dendrite
0.47	GO:0043235	receptor complex
0.45	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm

sp|P34082|FAS2_DROME
Fasciclin-2
Search

FAS2

0.76	Neural cell adhesion molecule

0.67	GO:0007155	cell adhesion
0.38	GO:1904800	negative regulation of neuron remodeling
0.38	GO:0001746	Bolwig's organ morphogenesis
0.37	GO:0035158	regulation of tube diameter, open tracheal system
0.37	GO:0072553	terminal button organization
0.37	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.37	GO:0072499	photoreceptor cell axon guidance
0.37	GO:0008355	olfactory learning
0.37	GO:0007614	short-term memory
0.37	GO:0016319	mushroom body development

0.34	GO:0005515	protein binding
0.32	GO:0004672	protein kinase activity
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0008144	drug binding

0.37	GO:0036062	presynaptic periactive zone
0.37	GO:0097482	muscle cell postsynaptic specialization
0.37	GO:0061174	type I terminal bouton
0.36	GO:0048786	presynaptic active zone
0.36	GO:0031225	anchored component of membrane
0.36	GO:0045211	postsynaptic membrane
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P34739|TTF2_DROME
Transcription termination factor 2
Search

0.59	Transcription termination factor 2

0.55	GO:0034454	microtubule anchoring at centrosome
0.55	GO:0007143	female meiotic nuclear division
0.52	GO:0007283	spermatogenesis
0.49	GO:0006353	DNA-templated transcription, termination
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0035082	axoneme assembly
0.32	GO:0006259	DNA metabolic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008094	DNA-dependent ATPase activity
0.37	GO:0004386	helicase activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0003677	DNA binding
0.33	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.32	GO:0003723	RNA binding

0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

EC:3.1.21

GO:0016888

sp|P35004|TRYB_DROME
Trypsin beta
Search

0.46	trypsin epsilon

0.61	GO:0006508	proteolysis
0.38	GO:0042060	wound healing
0.38	GO:0007599	hemostasis
0.38	GO:0050817	coagulation
0.33	GO:0007586	digestion

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005509	calcium ion binding

0.43	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P35005|TRYE_DROME
Trypsin epsilon
Search

0.46	Trypsin epsilon

0.61	GO:0006508	proteolysis
0.38	GO:0007596	blood coagulation

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005509	calcium ion binding

0.42	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P35122|UCHL_DROME
Ubiquitin carboxyl-terminal hydrolase
Search

0.55	Ubiquitin carboxyl-terminal hydrolase

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.45	GO:0016579	protein deubiquitination
0.36	GO:1904888	cranial skeletal system development
0.36	GO:0007219	Notch signaling pathway

0.80	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.32	GO:0046983	protein dimerization activity

0.45	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|P35128|UBE2N_DROME
Ubiquitin-conjugating enzyme E2 N
Search

0.47	Ubiquitin-conjugating enzyme

0.46	GO:0000209	protein polyubiquitination
0.44	GO:0007630	jump response
0.44	GO:0045977	positive regulation of mitotic cell cycle, embryonic
0.44	GO:0007629	flight behavior
0.44	GO:0007412	axon target recognition
0.44	GO:0061057	peptidoglycan recognition protein signaling pathway
0.44	GO:0060074	synapse maturation
0.44	GO:1902916	positive regulation of protein polyubiquitination
0.44	GO:0008594	photoreceptor cell morphogenesis
0.44	GO:0007625	grooming behavior

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.43	GO:0031624	ubiquitin conjugating enzyme binding
0.41	GO:0061659	ubiquitin-like protein ligase activity
0.36	GO:0016874	ligase activity

0.44	GO:0035370	UBC13-UEV1A complex
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005634	nucleus
0.34	GO:0000151	ubiquitin ligase complex
0.33	GO:0005829	cytosol

0.36	EC:6	GO:0016874
0.44	KEGG:R03876	GO:0004842

sp|P35220|CTNA_DROME
Catenin alpha
Search

0.74	Catenin alpha

0.72	GO:0007155	cell adhesion
0.47	GO:0046664	dorsal closure, amnioserosa morphology change
0.46	GO:0060322	head development
0.46	GO:0003383	apical constriction
0.45	GO:0034333	adherens junction assembly
0.45	GO:0010171	body morphogenesis
0.40	GO:0007417	central nervous system development
0.40	GO:0009887	animal organ morphogenesis
0.37	GO:0007010	cytoskeleton organization
0.37	GO:0097435	supramolecular fiber organization

0.82	GO:0045296	cadherin binding
0.78	GO:0051015	actin filament binding
0.57	GO:0005198	structural molecule activity
0.42	GO:0042802	identical protein binding
0.38	GO:0008013	beta-catenin binding

0.68	GO:0015629	actin cytoskeleton
0.48	GO:0005912	adherens junction
0.45	GO:0005911	cell-cell junction
0.45	GO:0016342	catenin complex
0.36	GO:0005829	cytosol

sp|P35381|ATPA_DROME
ATP synthase subunit alpha, mitochondrial
Search

0.45	ATP synthase subunit alpha

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.43	GO:1902769	regulation of choline O-acetyltransferase activity
0.41	GO:0019915	lipid storage
0.40	GO:0040007	growth
0.36	GO:0022900	electron transport chain

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.34	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.30	GO:0016021	integral component of membrane

sp|P35415|MYSP1_DROME
Paramyosin, long form
Search

0.73	Myosin class II heavy chain

0.48	GO:0030239	myofibril assembly
0.47	GO:0007498	mesoderm development

0.73

GO:0003774

motor activity

0.77	GO:0016459	myosin complex
0.38	GO:0030016	myofibril
0.30	GO:0031224	intrinsic component of membrane

sp|P35421|PUR4_DROME
Phosphoribosylformylglycinamidine synthase
Search

PFAS

0.44	Phosphoribosylformylglycinamidine synthase

0.70	GO:0006189	'de novo' IMP biosynthetic process
0.39	GO:0006541	glutamine metabolic process
0.36	GO:0042493	response to drug

0.77	GO:0004642	phosphoribosylformylglycinamidine synthase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.33	GO:0016740	transferase activity

0.36	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:6.3.5.3	GO:0004642
0.77	KEGG:R04463	GO:0004642

sp|P35500|SCNA_DROME
Sodium channel protein para
Search

0.69	Sodium channel protein para

0.78	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0035725	sodium ion transmembrane transport
0.36	GO:0045433	male courtship behavior, veined wing generated song production
0.36	GO:0007638	mechanosensory behavior
0.36	GO:0019228	neuronal action potential
0.35	GO:0086010	membrane depolarization during action potential
0.35	GO:0001666	response to hypoxia
0.35	GO:0060078	regulation of postsynaptic membrane potential

0.84	GO:0005248	voltage-gated sodium channel activity
0.75	GO:0022832	voltage-gated channel activity
0.73	GO:0022839	ion gated channel activity
0.72	GO:0008381	mechanosensitive ion channel activity
0.70	GO:0005509	calcium ion binding

0.84

GO:0001518

voltage-gated sodium channel complex

sp|P35554|FTN_DROME
Flightin
Search

FLN

0.97

Flightin

0.89	GO:0014703	oscillatory muscle contraction
0.87	GO:0030241	skeletal muscle myosin thick filament assembly
0.87	GO:0007527	adult somatic muscle development
0.85	GO:0045214	sarcomere organization

0.87	GO:0097493	structural molecule activity conferring elasticity
0.86	GO:0008307	structural constituent of muscle

0.87	GO:0005863	striated muscle myosin thick filament
0.85	GO:0031672	A band

sp|P35600|RFC1_DROME
Replication factor C subunit 1
Search

RFC1

0.72	Replication factor C subunit 1

0.66	GO:0006260	DNA replication
0.65	GO:0006281	DNA repair
0.37	GO:0048813	dendrite morphogenesis
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0042769	DNA damage response, detection of DNA damage
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0007004	telomere maintenance via telomerase
0.34	GO:0043085	positive regulation of catalytic activity
0.33	GO:0022402	cell cycle process

0.84	GO:0003689	DNA clamp loader activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0019904	protein domain specific binding
0.36	GO:0003690	double-stranded DNA binding
0.35	GO:0043565	sequence-specific DNA binding
0.34	GO:0008047	enzyme activator activity

0.84	GO:0005663	DNA replication factor C complex
0.57	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm

sp|P35820|PSC_DROME
Polycomb group protein Psc
Search

0.67	polycomb group protein Psc

0.78	GO:0035186	syncytial blastoderm mitotic cell cycle
0.72	GO:0006325	chromatin organization
0.71	GO:0048731	system development
0.71	GO:0009653	anatomical structure morphogenesis
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.70	GO:0045814	negative regulation of gene expression, epigenetic
0.67	GO:0016458	gene silencing
0.66	GO:0120036	plasma membrane bounded cell projection organization
0.65	GO:0048468	cell development
0.62	GO:0070301	cellular response to hydrogen peroxide

0.77	GO:0003682	chromatin binding
0.50	GO:0003677	DNA binding
0.43	GO:0097027	ubiquitin-protein transferase activator activity
0.38	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity

0.84	GO:0035102	PRC1 complex
0.77	GO:0005704	polytene chromosome band
0.66	GO:0001739	sex chromatin
0.59	GO:0016604	nuclear body
0.34	GO:0070701	mucus layer
0.30	GO:0005725	intercalary heterochromatin
0.30	GO:0016020	membrane

sp|P35832|PTP99_DROME
Tyrosine-protein phosphatase 99A
Search

0.39	S-adenosyl-methyl transferase mraw

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.39	GO:0007415	defasciculation of motor neuron axon
0.38	GO:0007409	axonogenesis
0.37	GO:0097485	neuron projection guidance
0.35	GO:0070445	regulation of oligodendrocyte progenitor proliferation
0.35	GO:0048709	oligodendrocyte differentiation
0.35	GO:0002244	hematopoietic progenitor cell differentiation
0.34	GO:0007611	learning or memory
0.34	GO:0006468	protein phosphorylation
0.33	GO:0032259	methylation

0.74	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0019198	transmembrane receptor protein phosphatase activity
0.37	GO:0050254	rhodopsin kinase activity
0.35	GO:0016162	cellulose 1,4-beta-cellobiosidase activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding

0.37	GO:0030424	axon
0.35	GO:0072534	perineuronal net
0.34	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74

GO:0004725

sp|P35875|PARP_DROME
Poly [ADP-ribose] polymerase
Search

0.57	Poly [ADP-ribose] polymerase

0.83	GO:0006471	protein ADP-ribosylation
0.50	GO:1990966	ATP generation from poly-ADP-D-ribose
0.50	GO:1903827	regulation of cellular protein localization
0.50	GO:0035080	heat shock-mediated polytene chromosome puffing
0.49	GO:1903518	positive regulation of single strand break repair
0.49	GO:2001170	negative regulation of ATP biosynthetic process
0.49	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.49	GO:0006963	positive regulation of antibacterial peptide biosynthetic process
0.48	GO:0030576	Cajal body organization
0.48	GO:0043504	mitochondrial DNA repair

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.64	GO:0051287	NAD binding
0.61	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.50	GO:1990404	protein ADP-ribosylase activity
0.47	GO:0047485	protein N-terminus binding
0.45	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0042393	histone binding
0.45	GO:0019901	protein kinase binding
0.44	GO:0001067	regulatory region nucleic acid binding

0.58	GO:0005634	nucleus
0.48	GO:0005703	polytene chromosome puff
0.47	GO:0000791	euchromatin
0.46	GO:0070013	intracellular organelle lumen
0.44	GO:0005667	transcription factor complex
0.43	GO:0032993	protein-DNA complex
0.42	GO:0012505	endomembrane system
0.40	GO:0031967	organelle envelope
0.39	GO:0005739	mitochondrion
0.33	GO:0000781	chromosome, telomeric region

0.81

EC:2.4.2.30

GO:0003950

sp|P35992|PTP10_DROME
Tyrosine-protein phosphatase 10D
Search

0.37	Receptor protein-tyrosine phosphatase 10d

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.56	GO:0008045	motor neuron axon guidance
0.55	GO:0007424	open tracheal system development
0.52	GO:0007417	central nervous system development
0.52	GO:0007616	long-term memory

0.74	GO:0004725	protein tyrosine phosphatase activity
0.43	GO:0019198	transmembrane receptor protein phosphatase activity

0.53	GO:0045177	apical part of cell
0.53	GO:0030424	axon
0.43	GO:0043025	neuronal cell body
0.42	GO:0098590	plasma membrane region
0.30	GO:0016021	integral component of membrane

0.74

GO:0004725

sp|P36179|2AAA_DROME
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit
Search

0.84	Serine/threonine protein phosphatase 2a regulatory subunit a

0.58	GO:0007099	centriole replication
0.56	GO:0051225	spindle assembly
0.56	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.56	GO:0007623	circadian rhythm
0.55	GO:0060561	apoptotic process involved in morphogenesis
0.54	GO:0043666	regulation of phosphoprotein phosphatase activity
0.54	GO:0006914	autophagy
0.51	GO:0007059	chromosome segregation
0.51	GO:0006629	lipid metabolic process
0.51	GO:0006470	protein dephosphorylation

0.56	GO:0052689	carboxylic ester hydrolase activity
0.55	GO:0019888	protein phosphatase regulator activity
0.48	GO:0008408	3'-5' exonuclease activity
0.39	GO:0003676	nucleic acid binding

0.56	GO:0005814	centriole
0.55	GO:0000159	protein phosphatase type 2A complex
0.53	GO:0005576	extracellular region
0.52	GO:0045121	membrane raft
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol

0.56	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.56	KEGG:R00630	GO:0052689

sp|P36188|TNNI_DROME
Troponin I
Search

WUPA

0.87	Troponin I

0.37	GO:0046716	muscle cell cellular homeostasis
0.37	GO:0045214	sarcomere organization
0.37	GO:0060047	heart contraction
0.37	GO:0048738	cardiac muscle tissue development
0.37	GO:0007519	skeletal muscle tissue development
0.36	GO:0006936	muscle contraction
0.36	GO:0000280	nuclear division
0.36	GO:0007399	nervous system development

0.34	GO:0003779	actin binding
0.33	GO:0046872	metal ion binding

0.84	GO:0005861	troponin complex
0.34	GO:0005634	nucleus

sp|P36192|DEFI_DROME
Defensin
Search

0.71	Defensin B J

0.72	GO:0006952	defense response
0.53	GO:0019730	antimicrobial humoral response
0.52	GO:0009617	response to bacterium
0.35	GO:0009620	response to fungus
0.35	GO:0031640	killing of cells of other organism

0.52	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P36193|DROS_DROME
Drosocin
Search

0.85	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.83	GO:0019731	antibacterial humoral response
0.81	GO:0050830	defense response to Gram-positive bacterium
0.80	GO:0050829	defense response to Gram-negative bacterium
0.52	GO:0045087	innate immune response

0.66

GO:0005576

extracellular region

sp|P36241|RL19_DROME
60S ribosomal protein L19
Search

0.67	Ribosomal protein L19

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.33	GO:0006289	nucleotide-excision repair

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding
0.33	GO:0003684	damaged DNA binding
0.33	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

0.79	GO:0022625	cytosolic large ribosomal subunit
0.33	GO:0005634	nucleus

0.33

EC:6.3.5.5

GO:0004088

sp|P36872|2ABA_DROME
Protein phosphatase PP2A 55 kDa regulatory subunit
Search

0.66	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.49	GO:0045201	maintenance of neuroblast polarity
0.48	GO:0007091	metaphase/anaphase transition of mitotic cell cycle
0.48	GO:0007406	negative regulation of neuroblast proliferation
0.47	GO:0007447	imaginal disc pattern formation
0.46	GO:0001700	embryonic development via the syncytial blastoderm
0.46	GO:0007099	centriole replication
0.46	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.45	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.45	GO:0050821	protein stabilization

0.80	GO:0019888	protein phosphatase regulator activity
0.45	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0004386	helicase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.39	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P36951|HYI_DROME
Putative hydroxypyruvate isomerase
Search

0.54	Hydroxypyruvate isomerase

0.36	GO:0046487	glyoxylate metabolic process
0.34	GO:0050909	sensory perception of taste

0.70	GO:0008903	hydroxypyruvate isomerase activity
0.35	GO:0047610	acetylsalicylate deacetylase activity

0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.70	EC:5.3.1.22	GO:0008903
0.70	KEGG:R01394	GO:0008903

sp|P36958|RPB9_DROME
DNA-directed RNA polymerase II subunit RPB9
Search

0.51	DNA-directed RNA polymerase subunit

0.81	GO:0006379	mRNA cleavage
0.58	GO:0006351	transcription, DNA-templated
0.44	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0030329	prenylcysteine metabolic process
0.34	GO:0000098	sulfur amino acid catabolic process
0.34	GO:0035019	somatic stem cell population maintenance
0.34	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0000278	mitotic cell cycle

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.34	GO:0001735	prenylcysteine oxidase activity

0.70	GO:0005730	nucleolus
0.54	GO:0005665	DNA-directed RNA polymerase II, core complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

sp|P36975|SNP25_DROME
Synaptosomal-associated protein 25
Search

0.77	Synaptosomal-associated protein 25

0.78	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane
0.77	GO:0016082	synaptic vesicle priming
0.72	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.70	GO:0007274	neuromuscular synaptic transmission
0.47	GO:0006893	Golgi to plasma membrane transport
0.45	GO:0016081	synaptic vesicle docking

0.71	GO:0000149	SNARE binding
0.71	GO:0005484	SNAP receptor activity

0.72	GO:0031201	SNARE complex
0.69	GO:0043195	terminal bouton
0.66	GO:0030667	secretory granule membrane
0.44	GO:0031083	BLOC-1 complex
0.42	GO:0005886	plasma membrane
0.41	GO:0030054	cell junction

sp|P37159|LYSE_DROME
Lysozyme E
Search

0.53	Lysozyme E

0.43	GO:0050830	defense response to Gram-positive bacterium
0.43	GO:0050829	defense response to Gram-negative bacterium
0.42	GO:0019835	cytolysis
0.42	GO:0016998	cell wall macromolecule catabolic process
0.34	GO:0045824	negative regulation of innate immune response

0.77	GO:0003796	lysozyme activity
0.35	GO:0004568	chitinase activity

0.41	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0003796

sp|P37160|LYSS_DROME
Lysozyme S
Search

0.54	Lysozyme S

0.43	GO:0050830	defense response to Gram-positive bacterium
0.42	GO:0050829	defense response to Gram-negative bacterium
0.42	GO:0019835	cytolysis
0.41	GO:0016998	cell wall macromolecule catabolic process
0.34	GO:0045824	negative regulation of innate immune response
0.33	GO:0031640	killing of cells of other organism

0.77	GO:0003796	lysozyme activity
0.35	GO:0004568	chitinase activity
0.33	GO:0042802	identical protein binding

0.40	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0003796

sp|P37161|LYSX_DROME
Lysozyme X
Search

0.53	Lysozyme X

0.42	GO:0050830	defense response to Gram-positive bacterium
0.42	GO:0050829	defense response to Gram-negative bacterium
0.41	GO:0019835	cytolysis
0.41	GO:0016998	cell wall macromolecule catabolic process
0.34	GO:0045824	negative regulation of innate immune response

0.77	GO:0003796	lysozyme activity
0.35	GO:0004568	chitinase activity

0.40	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0003796

sp|P37193|ADXH_DROME
Adrenodoxin-like protein, mitochondrial
Search

0.37	Adrenodoxin protein, mitochondrial

0.61	GO:0022900	electron transport chain
0.49	GO:0045966	positive regulation of ecdysteroid metabolic process
0.49	GO:0007554	regulation of ecdysteroid biosynthetic process
0.49	GO:0090031	positive regulation of steroid hormone biosynthetic process
0.48	GO:0035073	pupariation
0.34	GO:0006700	C21-steroid hormone biosynthetic process
0.33	GO:0016125	sterol metabolic process
0.32	GO:0006508	proteolysis
0.32	GO:0044281	small molecule metabolic process

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.34	GO:0046872	metal ion binding
0.33	GO:0016805	dipeptidase activity
0.33	GO:0008237	metallopeptidase activity
0.32	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.37

GO:0005759

mitochondrial matrix

0.33

EC:3.4.13

GO:0016805

sp|P37236|FREQ_DROME
Frequenin-1
Search

0.53

Frequenin

0.51	GO:0007528	neuromuscular junction development
0.48	GO:0007268	chemical synaptic transmission
0.46	GO:0046928	regulation of neurotransmitter secretion
0.46	GO:0031284	positive regulation of guanylate cyclase activity
0.45	GO:0099643	signal release from synapse
0.43	GO:0006836	neurotransmitter transport
0.41	GO:0051649	establishment of localization in cell
0.38	GO:0048752	semicircular canal morphogenesis
0.37	GO:0010446	response to alkaline pH
0.37	GO:0007635	chemosensory behavior

0.70	GO:0005509	calcium ion binding
0.46	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.36	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0016174	NAD(P)H oxidase activity
0.33	GO:0008236	serine-type peptidase activity
0.33	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.33	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity

0.45	GO:0097458	neuron part
0.44	GO:0044456	synapse part
0.36	GO:0044297	cell body
0.36	GO:0032279	asymmetric synapse
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0012505	endomembrane system
0.35	GO:0098590	plasma membrane region
0.35	GO:0030054	cell junction
0.34	GO:0099503	secretory vesicle
0.34	GO:0120038	plasma membrane bounded cell projection part

0.34

EC:1.6.3.1

GO:0016174

sp|P37276|DYHC_DROME
Dynein heavy chain, cytoplasmic
Search

0.59	Dynein heavy chain, cytoplasmic

0.74	GO:0007018	microtubule-based movement
0.38	GO:0099518	vesicle cytoskeletal trafficking
0.37	GO:0031122	cytoplasmic microtubule organization
0.36	GO:1904801	positive regulation of neuron remodeling
0.36	GO:0051237	maintenance of RNA location
0.36	GO:0007312	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification
0.36	GO:0030723	ovarian fusome organization
0.36	GO:0007279	pole cell formation
0.36	GO:0007282	cystoblast division
0.36	GO:0051683	establishment of Golgi localization

0.75	GO:0003777	microtubule motor activity
0.60	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0045503	dynein light chain binding
0.38	GO:0051959	dynein light intermediate chain binding
0.38	GO:0045505	dynein intermediate chain binding
0.35	GO:0003993	acid phosphatase activity

0.77	GO:0030286	dynein complex
0.35	GO:0045169	fusome
0.35	GO:1904115	axon cytoplasm
0.34	GO:0000776	kinetochore
0.34	GO:0005938	cell cortex
0.34	GO:0005874	microtubule
0.34	GO:0005794	Golgi apparatus
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.60

GO:0016887

sp|P38040|GBG1_DROME
Guanine nucleotide-binding protein subunit gamma-1
Search

0.59	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0003371	establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration
0.51	GO:0003379	establishment of cell polarity involved in gastrulation cell migration
0.51	GO:0048383	mesectoderm development
0.50	GO:0007637	proboscis extension reflex
0.50	GO:0043519	regulation of myosin II filament organization
0.50	GO:0061343	cell adhesion involved in heart morphogenesis
0.49	GO:0055059	asymmetric neuroblast division
0.49	GO:0060027	convergent extension involved in gastrulation
0.48	GO:0007391	dorsal closure

0.64	GO:0004871	signal transducer activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0036094	small molecule binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0043168	anion binding
0.34	GO:0008144	drug binding
0.33	GO:0008408	3'-5' exonuclease activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.36	GO:0005874	microtubule
0.36	GO:0016035	zeta DNA polymerase complex
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0003887

sp|P38979|RSSA_DROME
40S ribosomal protein SA
Search

0.60	40S ribosomal protein SA

0.77	GO:0000028	ribosomal small subunit assembly
0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.44	GO:0007275	multicellular organism development
0.39	GO:0006407	rRNA export from nucleus
0.36	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.36	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0043022	ribosome binding

0.73	GO:0022627	cytosolic small ribosomal subunit
0.41	GO:0005634	nucleus
0.38	GO:0030686	90S preribosome
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|P39018|RS19A_DROME
40S ribosomal protein S19a
Search

0.50	Ribosomal protein S19

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.39	GO:0000028	ribosomal small subunit assembly
0.35	GO:0035283	central nervous system segmentation
0.34	GO:0020027	hemoglobin metabolic process
0.34	GO:0048821	erythrocyte development
0.34	GO:0045646	regulation of erythrocyte differentiation
0.34	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003677	DNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part
0.34	GO:0030008	TRAPP complex
0.33	GO:0005794	Golgi apparatus
0.33	GO:0099512	supramolecular fiber
0.33	GO:0015630	microtubule cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|P39205|CIN_DROME
Molybdenum cofactor synthesis protein cinnamon
Search

CIN

0.47	Molybdenum cofactor synthesis protein cinnamon

0.78	GO:0032324	molybdopterin cofactor biosynthetic process
0.69	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.41	GO:0018315	molybdenum incorporation into molybdenum-molybdopterin complex
0.39	GO:0072579	glycine receptor clustering
0.38	GO:0006486	protein glycosylation
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:0006508	proteolysis

0.40	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.40	GO:0061598	molybdopterin adenylyltransferase activity
0.40	GO:0061599	molybdopterin molybdotransferase activity
0.36	GO:0046872	metal ion binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0000139	Golgi membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40

EC:2.4.1.135

GO:0015018

sp|P39413|AEF1_DROME
Adult enhancer factor 1
Search

0.84	Adult enhancer factor 1

0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.34	GO:0040034	regulation of development, heterochronic
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0007010	cytoskeleton organization
0.33	GO:0022604	regulation of cell morphogenesis
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0060041	retina development in camera-type eye
0.32	GO:0016567	protein ubiquitination

0.51	GO:0003676	nucleic acid binding
0.42	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0061630	ubiquitin protein ligase activity

0.38	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle
0.34	GO:0019013	viral nucleocapsid
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:1902493	acetyltransferase complex
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043234	protein complex
0.32	GO:0044422	organelle part

sp|P39572|GIANT_DROME
Protein giant
Search

0.71	GO:0007381	specification of segmental identity, labial segment
0.69	GO:0035271	ring gland development
0.69	GO:0044324	regulation of transcription involved in anterior/posterior axis specification
0.67	GO:0007362	terminal region determination
0.67	GO:0008293	torso signaling pathway
0.66	GO:0040015	negative regulation of multicellular organism growth
0.61	GO:0008361	regulation of cell size
0.61	GO:0007411	axon guidance
0.59	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0007431	salivary gland development

0.64	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.63	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity
0.33	GO:0043425	bHLH transcription factor binding
0.33	GO:0008239	dipeptidyl-peptidase activity
0.33	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0003735	structural constituent of ribosome

0.56	GO:0005634	nucleus
0.33	GO:0005700	polytene chromosome
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0005938	cell cortex
0.32	GO:0032991	macromolecular complex
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

sp|P39736|BX42_DROME
Puff-specific protein Bx42
Search

0.86	Nuclear protein skip

0.75	GO:0000398	mRNA splicing, via spliceosome
0.47	GO:0035214	eye-antennal disc development
0.47	GO:0001700	embryonic development via the syncytial blastoderm
0.39	GO:0014029	neural crest formation
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.38	GO:0090287	regulation of cellular response to growth factor stimulus
0.37	GO:0022618	ribonucleoprotein complex assembly
0.35	GO:0014010	Schwann cell proliferation
0.34	GO:0006072	glycerol-3-phosphate metabolic process

0.37	GO:0003712	transcription cofactor activity
0.34	GO:0005515	protein binding
0.34	GO:0004370	glycerol kinase activity
0.34	GO:0070403	NAD+ binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0003677	DNA binding
0.32	GO:0005524	ATP binding

0.76	GO:0005681	spliceosomal complex
0.46	GO:0000974	Prp19 complex
0.41	GO:0071141	SMAD protein complex
0.37	GO:0031981	nuclear lumen
0.35	GO:1902494	catalytic complex
0.35	GO:0000785	chromatin
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34	EC:2.7.1.30	GO:0004370
0.34	KEGG:R00847	GO:0004370

sp|P39768|OPA_DROME
Pair-rule protein odd-paired
Search

0.90	Pair-rule protein odd-paired

0.47	GO:0008101	decapentaplegic signaling pathway
0.47	GO:0007455	eye-antennal disc morphogenesis
0.47	GO:0007494	midgut development
0.47	GO:0008354	germ cell migration
0.44	GO:0006366	transcription by RNA polymerase II
0.44	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0007420	brain development
0.40	GO:0009790	embryo development
0.40	GO:0007389	pattern specification process
0.39	GO:0061351	neural precursor cell proliferation

0.51	GO:0003676	nucleic acid binding
0.47	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.41	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P39769|PHP_DROME
Polyhomeotic-proximal chromatin protein
Search

0.93	polyhomeotic-proximal chromatin protein-like

0.62	GO:0035186	syncytial blastoderm mitotic cell cycle
0.52	GO:0016458	gene silencing
0.51	GO:0045892	negative regulation of transcription, DNA-templated
0.50	GO:0030708	germarium-derived female germ-line cyst encapsulation
0.50	GO:0030713	ovarian follicle cell stalk formation
0.48	GO:0035075	response to ecdysone
0.47	GO:0021954	central nervous system neuron development
0.47	GO:0045814	negative regulation of gene expression, epigenetic
0.47	GO:0051276	chromosome organization
0.45	GO:0140014	mitotic nuclear division

0.62	GO:0008270	zinc ion binding
0.54	GO:0051087	chaperone binding
0.54	GO:0003682	chromatin binding
0.50	GO:0044547	DNA topoisomerase binding
0.37	GO:0003677	DNA binding
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0001095	TFIIE-class transcription factor binding
0.33	GO:0001088	transcription factor activity, TFIIE-class binding
0.33	GO:0003743	translation initiation factor activity

0.61	GO:0005634	nucleus
0.54	GO:0000151	ubiquitin ligase complex
0.49	GO:0070013	intracellular organelle lumen
0.45	GO:0043234	protein complex
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.32	GO:0031248	protein acetyltransferase complex
0.32	GO:1905368	peptidase complex
0.30	GO:0016020	membrane

0.33	EC:3.1	GO:0004518
0.34	KEGG:R03876	GO:0004842

sp|P39770|SALM_DROME
Homeotic protein spalt-major
Search

0.63	Homeotic protein spalt-major

0.52	GO:0035155	negative regulation of terminal cell fate specification, open tracheal system
0.51	GO:0035310	notum cell fate specification
0.51	GO:0048098	antennal joint development
0.51	GO:0007438	oenocyte development
0.51	GO:0045465	R8 cell differentiation
0.50	GO:0035277	spiracle morphogenesis, open tracheal system
0.50	GO:0045466	R7 cell differentiation
0.49	GO:0030539	male genitalia development
0.49	GO:0007525	somatic muscle development
0.48	GO:0048644	muscle organ morphogenesis

0.51	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding
0.30	GO:0003700	DNA binding transcription factor activity

0.41

GO:0005634

nucleus

sp|P40139|NG2_DROME
Protein new-glue 2
Search

0.41	GO:0030245	cellulose catabolic process
0.41	GO:0007264	small GTPase mediated signal transduction
0.39	GO:0016573	histone acetylation
0.39	GO:0065009	regulation of molecular function
0.38	GO:0071555	cell wall organization
0.37	GO:0006508	proteolysis
0.36	GO:0034765	regulation of ion transmembrane transport
0.36	GO:0006629	lipid metabolic process
0.36	GO:0070588	calcium ion transmembrane transport
0.35	GO:0006355	regulation of transcription, DNA-templated

0.45	GO:0030248	cellulose binding
0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.41	GO:0005085	guanyl-nucleotide exchange factor activity
0.39	GO:0004402	histone acetyltransferase activity
0.39	GO:0003712	transcription cofactor activity
0.38	GO:0008270	zinc ion binding
0.37	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.37	GO:0045330	aspartyl esterase activity
0.37	GO:0030599	pectinesterase activity
0.37	GO:0005245	voltage-gated calcium channel activity

0.50	GO:0005576	extracellular region
0.38	GO:0005618	cell wall
0.37	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0009897	external side of plasma membrane
0.37	GO:0005891	voltage-gated calcium channel complex
0.36	GO:0005634	nucleus
0.36	GO:0031982	vesicle

0.42

EC:3.2.1

GO:0004553

sp|P40140|NG3_DROME
Protein new-glue 3
Search

0.42	GO:0006367	transcription initiation from RNA polymerase II promoter
0.42	GO:0007264	small GTPase mediated signal transduction
0.40	GO:0005975	carbohydrate metabolic process
0.39	GO:0065009	regulation of molecular function
0.39	GO:0007399	nervous system development
0.38	GO:0030154	cell differentiation
0.37	GO:0016192	vesicle-mediated transport
0.37	GO:0009057	macromolecule catabolic process
0.36	GO:0006629	lipid metabolic process

0.42	GO:0005085	guanyl-nucleotide exchange factor activity
0.40	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0008081	phosphoric diester hydrolase activity
0.36	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.35	GO:0003723	RNA binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0005576	extracellular region
0.43	GO:0005672	transcription factor TFIIA complex
0.40	GO:0030008	TRAPP complex
0.30	GO:0016020	membrane

0.40

EC:3.2.1

GO:0004553

sp|P40141|NG4_DROME
Protein new-glue 4
Search

0.66

GO:0005576

extracellular region

sp|P40301|PSA2_DROME
Proteasome subunit alpha type-2
Search

0.48	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.68	GO:0043632	modification-dependent macromolecule catabolic process
0.35	GO:0008063	Toll signaling pathway
0.35	GO:0007623	circadian rhythm

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.58	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P40304|PSB1_DROME
Proteasome subunit beta type-1
Search

0.47	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.42	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0008063	Toll signaling pathway
0.35	GO:0009817	defense response to fungus, incompatible interaction
0.35	GO:0007623	circadian rhythm

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.76	GO:0005839	proteasome core complex
0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.35	GO:0048046	apoplast
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P40320|METK_DROME
S-adenosylmethionine synthase
Search

0.57	S-adenosylmethionine synthase

0.79	GO:0006556	S-adenosylmethionine biosynthetic process
0.72	GO:0006730	one-carbon metabolic process
0.47	GO:0008340	determination of adult lifespan

0.79	GO:0004478	methionine adenosyltransferase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding

0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.5.1.6

GO:0004478

sp|P40417|ERKA_DROME
Mitogen-activated protein kinase ERK-A
Search

0.58	Mitogen-activated protein kinase ERK-A

0.79	GO:0000165	MAPK cascade
0.53	GO:0071276	cellular response to cadmium ion
0.52	GO:2000656	regulation of apolipoprotein binding
0.51	GO:0016241	regulation of macroautophagy
0.51	GO:0031098	stress-activated protein kinase signaling cascade
0.50	GO:0033129	positive regulation of histone phosphorylation
0.50	GO:0060440	trachea formation
0.50	GO:1905050	positive regulation of metallopeptidase activity
0.50	GO:0006975	DNA damage induced protein phosphorylation
0.50	GO:0002741	positive regulation of cytokine secretion involved in immune response

0.81	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.49	GO:0004708	MAP kinase kinase activity
0.48	GO:0001784	phosphotyrosine residue binding
0.47	GO:0019902	phosphatase binding
0.44	GO:0042802	identical protein binding
0.41	GO:0019901	protein kinase binding

0.49	GO:0031143	pseudopodium
0.46	GO:0005829	cytosol
0.45	GO:0005635	nuclear envelope
0.45	GO:0030054	cell junction
0.43	GO:0005901	caveola
0.43	GO:0031594	neuromuscular junction
0.42	GO:0005770	late endosome
0.42	GO:0005769	early endosome
0.40	GO:0005794	Golgi apparatus
0.39	GO:0005856	cytoskeleton

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P40421|RDGC_DROME
Serine/threonine-protein phosphatase rdgC
Search

0.51	Serine/threonine-protein phosphatase rdgC

0.72	GO:0050906	detection of stimulus involved in sensory perception
0.71	GO:0006470	protein dephosphorylation
0.37	GO:0016059	deactivation of rhodopsin mediated signaling
0.37	GO:0043052	thermotaxis
0.36	GO:0019722	calcium-mediated signaling
0.36	GO:0007602	phototransduction
0.36	GO:0007601	visual perception
0.35	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.35	GO:0043409	negative regulation of MAPK cascade
0.32	GO:0055114	oxidation-reduction process

0.72	GO:0004721	phosphoprotein phosphatase activity
0.70	GO:0030145	manganese ion binding
0.69	GO:0005509	calcium ion binding
0.60	GO:0005506	iron ion binding
0.36	GO:0005516	calmodulin binding
0.36	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.36	GO:0051879	Hsp90 protein binding
0.36	GO:0030544	Hsp70 protein binding
0.32	GO:0016491	oxidoreductase activity

0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.72

GO:0004721

sp|P40423|SQH_DROME
Myosin regulatory light chain sqh
Search

0.67	Myosin regulatory light chain sqh

0.50	GO:0019749	cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte
0.49	GO:0031036	myosin II filament assembly
0.49	GO:0035191	nuclear axial expansion
0.49	GO:0060288	formation of a compartment boundary
0.49	GO:0060289	compartment boundary maintenance
0.48	GO:0090254	cell elongation involved in imaginal disc-derived wing morphogenesis
0.48	GO:0003384	apical constriction involved in gastrulation
0.48	GO:0035277	spiracle morphogenesis, open tracheal system
0.48	GO:0035159	regulation of tube length, open tracheal system
0.47	GO:0035317	imaginal disc-derived wing hair organization

0.70	GO:0005509	calcium ion binding
0.48	GO:0032036	myosin heavy chain binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0004721	phosphoprotein phosphatase activity

0.49	GO:0106037	apicomedial cortex
0.49	GO:0035183	female germline ring canal inner rim
0.47	GO:0016460	myosin II complex
0.47	GO:0031941	filamentous actin
0.46	GO:0032154	cleavage furrow
0.46	GO:0051233	spindle midzone
0.46	GO:0030496	midbody
0.45	GO:0016324	apical plasma membrane
0.45	GO:0005912	adherens junction
0.44	GO:0048471	perinuclear region of cytoplasm

0.33

GO:0004721

sp|P40427|EXD_DROME
Homeobox protein extradenticle
Search

EXD

0.90	Pre-B-cell leukemia transcription factor

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0007438	oenocyte development
0.46	GO:0000060	protein import into nucleus, translocation
0.46	GO:0007525	somatic muscle development
0.46	GO:0042659	regulation of cell fate specification
0.45	GO:0007422	peripheral nervous system development
0.44	GO:0001654	eye development
0.43	GO:0007420	brain development

0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.45	GO:0033613	activating transcription factor binding
0.45	GO:0035326	enhancer binding
0.43	GO:0003713	transcription coactivator activity
0.42	GO:0046982	protein heterodimerization activity
0.33	GO:0004801	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.41	GO:0032993	protein-DNA complex
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

EC:2.2.1.2

GO:0004801

sp|P40589|WNT4_DROME
Protein Wnt-4
Search

0.74	GO:0016055	Wnt signaling pathway
0.68	GO:0007275	multicellular organism development
0.62	GO:0035206	regulation of hemocyte proliferation
0.60	GO:0050919	negative chemotaxis
0.59	GO:0001736	establishment of planar polarity
0.57	GO:0007548	sex differentiation
0.56	GO:0008037	cell recognition
0.56	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.56	GO:0000904	cell morphogenesis involved in differentiation
0.55	GO:0016477	cell migration

0.70	GO:0005102	receptor binding
0.37	GO:0003743	translation initiation factor activity
0.36	GO:0140110	transcription regulator activity
0.36	GO:0004871	signal transducer activity
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0017076	purine nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding

0.73	GO:0005578	proteinaceous extracellular matrix
0.54	GO:0009986	cell surface
0.38	GO:0005615	extracellular space
0.36	GO:0005669	transcription factor TFIID complex
0.33	GO:0016592	mediator complex
0.32	GO:0030286	dynein complex
0.32	GO:0008076	voltage-gated potassium channel complex
0.32	GO:0005789	endoplasmic reticulum membrane
0.31	GO:0005739	mitochondrion

0.32

EC:3.1.1.5

GO:0004622

sp|P40656|SOX14_DROME
Putative transcription factor SOX-14
Search

0.69	Sox box protein 14, isoform C

0.58	GO:1904799	regulation of neuron remodeling
0.56	GO:0016322	neuron remodeling
0.55	GO:0048813	dendrite morphogenesis
0.54	GO:0007552	metamorphosis
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0048598	embryonic morphogenesis
0.40	GO:0048729	tissue morphogenesis
0.40	GO:0045165	cell fate commitment
0.40	GO:0006366	transcription by RNA polymerase II
0.39	GO:0048646	anatomical structure formation involved in morphogenesis

0.55	GO:0008301	DNA binding, bending
0.46	GO:0043565	sequence-specific DNA binding
0.42	GO:0140110	transcription regulator activity
0.37	GO:0001047	core promoter binding
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0005739	mitochondrion
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P40657|SOX15_DROME
Putative transcription factor SOX-15
Search

SOX15

0.82	Putative transcription factor SOX-15

0.64	GO:0022416	chaeta development
0.62	GO:0035220	wing disc development
0.60	GO:0000122	negative regulation of transcription by RNA polymerase II
0.59	GO:0042127	regulation of cell proliferation
0.58	GO:0043066	negative regulation of apoptotic process
0.44	GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification
0.44	GO:0003142	cardiogenic plate morphogenesis
0.44	GO:0060913	cardiac cell fate determination
0.44	GO:0001828	inner cell mass cellular morphogenesis
0.44	GO:0007493	endodermal cell fate determination

0.55	GO:0003677	DNA binding
0.42	GO:0008013	beta-catenin binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.41	GO:0003713	transcription coactivator activity
0.40	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0008134	transcription factor binding
0.40	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part

sp|P40688|SWA_DROME
Protein swallow
Search

0.87	GO:0007317	regulation of pole plasm oskar mRNA localization
0.86	GO:0019094	pole plasm mRNA localization
0.75	GO:0007015	actin filament organization
0.60	GO:0045450	bicoid mRNA localization
0.51	GO:0051301	cell division
0.51	GO:0007049	cell cycle

0.57	GO:0070840	dynein complex binding
0.53	GO:0003729	mRNA binding

0.48

GO:0005634

nucleus

sp|P40689|TSL_DROME
Torso-like protein
Search

LOC108744444

0.45

Torso

0.87	GO:0007278	pole cell fate determination
0.86	GO:0003384	apical constriction involved in gastrulation
0.86	GO:0007370	ventral furrow formation
0.86	GO:0007362	terminal region determination
0.86	GO:0008293	torso signaling pathway
0.85	GO:1902875	regulation of embryonic pattern specification
0.84	GO:0008358	maternal determination of anterior/posterior axis, embryo
0.84	GO:0040018	positive regulation of multicellular organism growth

0.65	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P40791|MEF2_DROME
Myocyte-specific enhancer factor 2
Search

0.81	Myocyte-specific enhancer factor

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.39	GO:0052576	carbohydrate storage
0.39	GO:0007496	anterior midgut development
0.38	GO:0045475	locomotor rhythm
0.38	GO:0007520	myoblast fusion
0.38	GO:0019730	antimicrobial humoral response
0.38	GO:0048747	muscle fiber development
0.37	GO:0016202	regulation of striated muscle tissue development
0.37	GO:0030707	ovarian follicle cell development

0.76	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.38	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.38	GO:0001158	enhancer sequence-specific DNA binding
0.37	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0004222	metalloendopeptidase activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.61

GO:0005634

nucleus

0.34

GO:0004222

sp|P40792|RAC1_DROME
Ras-related protein Rac1
Search

0.60	ADP ribosylation factor

0.77	GO:0007264	small GTPase mediated signal transduction
0.50	GO:0007394	dorsal closure, elongation of leading edge cells
0.50	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
0.50	GO:0035099	hemocyte migration
0.49	GO:0007426	tracheal outgrowth, open tracheal system
0.49	GO:0007390	germ-band shortening
0.49	GO:0035011	melanotic encapsulation of foreign target
0.49	GO:0034334	adherens junction maintenance
0.49	GO:0008258	head involution
0.49	GO:0046843	dorsal appendage formation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.45	GO:0019901	protein kinase binding
0.42	GO:0032794	GTPase activating protein binding
0.36	GO:0004003	ATP-dependent DNA helicase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0008144	drug binding

0.45	GO:0005622	intracellular
0.42	GO:0016028	rhabdomere
0.41	GO:0001726	ruffle
0.39	GO:0019897	extrinsic component of plasma membrane
0.39	GO:0099512	supramolecular fiber
0.36	GO:0043234	protein complex
0.36	GO:0043228	non-membrane-bounded organelle
0.36	GO:0044422	organelle part

sp|P40793|CDC42_DROME
Cdc42 homolog
Search

0.43	ADP ribosylation factor

0.77	GO:0007264	small GTPase mediated signal transduction
0.49	GO:0051301	cell division
0.49	GO:0051491	positive regulation of filopodium assembly
0.48	GO:0010592	positive regulation of lamellipodium assembly
0.47	GO:0048813	dendrite morphogenesis
0.47	GO:0006909	phagocytosis
0.46	GO:0009913	epidermal cell differentiation
0.46	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.46	GO:0030010	establishment of cell polarity
0.46	GO:0038189	neuropilin signaling pathway

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.46	GO:0032427	GBD domain binding
0.45	GO:0051022	Rho GDP-dissociation inhibitor binding
0.45	GO:0034191	apolipoprotein A-I receptor binding
0.45	GO:0019901	protein kinase binding
0.44	GO:0031996	thioesterase binding
0.44	GO:0030742	GTP-dependent protein binding
0.42	GO:0032794	GTPase activating protein binding
0.41	GO:0061630	ubiquitin protein ligase activity

0.46	GO:0045177	apical part of cell
0.45	GO:0005622	intracellular
0.45	GO:0043005	neuron projection
0.45	GO:0030054	cell junction
0.44	GO:0120038	plasma membrane bounded cell projection part
0.43	GO:0031256	leading edge membrane
0.43	GO:0030496	midbody
0.43	GO:0030175	filopodium
0.43	GO:0043209	myelin sheath
0.42	GO:0043025	neuronal cell body

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P40794|BNK_DROME
Protein bottleneck
Search

0.86	GO:0016476	regulation of embryonic cell shape
0.83	GO:0061572	actin filament bundle organization
0.51	GO:0007349	cellularization
0.50	GO:0044837	actomyosin contractile ring organization
0.50	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.44	GO:0061024	membrane organization

0.85	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.85	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.46	GO:0003779	actin binding

0.85	GO:0001725	stress fiber
0.83	GO:0005884	actin filament
0.37	GO:0005737	cytoplasm

sp|P40795|FOG_DROME
Protein folded gastrulation
Search

FOG

0.92	Folded gastrulation, isoform B

0.88	GO:0007374	posterior midgut invagination
0.87	GO:0048383	mesectoderm development
0.87	GO:0003384	apical constriction involved in gastrulation
0.87	GO:0060662	salivary gland cavitation
0.87	GO:0043519	regulation of myosin II filament organization
0.87	GO:0007509	mesoderm migration involved in gastrulation
0.86	GO:0007370	ventral furrow formation
0.86	GO:0007362	terminal region determination
0.86	GO:0008293	torso signaling pathway
0.85	GO:0040034	regulation of development, heterochronic

0.80	GO:0001664	G-protein coupled receptor binding
0.34	GO:0004222	metalloendopeptidase activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0046872	metal ion binding

0.51	GO:0005578	proteinaceous extracellular matrix
0.49	GO:0005737	cytoplasm
0.35	GO:0000131	incipient cellular bud site
0.35	GO:0009277	fungal-type cell wall
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004222

sp|P40796|LA_DROME
La protein homolog
Search

0.87	Sjogren syndrome antigen B (autoantigen La)

0.63	GO:0006396	RNA processing
0.35	GO:0031047	gene silencing by RNA
0.33	GO:0036093	germ cell proliferation
0.33	GO:0035562	negative regulation of chromatin binding
0.33	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.33	GO:0000122	negative regulation of transcription by RNA polymerase II
0.32	GO:0032259	methylation
0.32	GO:0006351	transcription, DNA-templated

0.61	GO:0008098	5S rRNA primary transcript binding
0.37	GO:0003729	mRNA binding
0.34	GO:0003677	DNA binding
0.32	GO:0008168	methyltransferase activity

0.61	GO:0005634	nucleus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.55	GO:0000791	euchromatin
0.34	GO:0019013	viral nucleocapsid
0.32	GO:0005737	cytoplasm
0.32	GO:0031974	membrane-enclosed lumen

0.32

GO:0008168

sp|P40797|PNUT_DROME
Protein peanut
Search

0.61

Septin

0.47	GO:0000281	mitotic cytokinesis
0.46	GO:0043065	positive regulation of apoptotic process
0.46	GO:0006915	apoptotic process
0.37	GO:0072114	pronephros morphogenesis
0.36	GO:0060271	cilium assembly
0.36	GO:0007349	cellularization
0.36	GO:0044837	actomyosin contractile ring organization
0.36	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0042803	protein homodimerization activity
0.45	GO:0008017	microtubule binding
0.44	GO:0003779	actin binding
0.42	GO:0003924	GTPase activity
0.33	GO:0003677	DNA binding

0.63	GO:0031105	septin complex
0.48	GO:0032154	cleavage furrow
0.48	GO:0045171	intercellular bridge
0.48	GO:0070938	contractile ring
0.39	GO:0005886	plasma membrane
0.35	GO:0005940	septin ring
0.35	GO:0045177	apical part of cell
0.33	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|P40798|STC_DROME
Protein shuttle craft
Search

0.74	Nuclear transcription factor, X-box-binding 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0045347	negative regulation of MHC class II biosynthetic process
0.39	GO:0006366	transcription by RNA polymerase II

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003676	nucleic acid binding

0.61	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P40807|DCOR1_DROME
Ornithine decarboxylase 1
Search

0.45	Pyridoxal-dependent decarboxylase

0.76	GO:0006596	polyamine biosynthetic process
0.48	GO:0009445	putrescine metabolic process
0.47	GO:0006591	ornithine metabolic process
0.45	GO:0048513	animal organ development
0.45	GO:0072001	renal system development
0.44	GO:0008284	positive regulation of cell proliferation
0.44	GO:0042176	regulation of protein catabolic process
0.44	GO:0009615	response to virus
0.41	GO:0042461	photoreceptor cell development
0.38	GO:0009653	anatomical structure morphogenesis

0.51	GO:0004586	ornithine decarboxylase activity
0.43	GO:0042803	protein homodimerization activity
0.37	GO:0018024	histone-lysine N-methyltransferase activity
0.35	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0008270	zinc ion binding

0.41	GO:0005829	cytosol
0.36	GO:0005694	chromosome
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005634	nucleus

0.51	EC:4.1.1.17	GO:0004586
0.51	KEGG:R00670	GO:0004586

sp|P40808|DCOR2_DROME
Ornithine decarboxylase 2
Search

0.42	Pyridoxal-dependent decarboxylase

0.76	GO:0006596	polyamine biosynthetic process
0.42	GO:0034968	histone lysine methylation
0.41	GO:0006470	protein dephosphorylation
0.40	GO:0009445	putrescine metabolic process
0.39	GO:0006591	ornithine metabolic process

0.43	GO:0004586	ornithine decarboxylase activity
0.42	GO:0018024	histone-lysine N-methyltransferase activity
0.41	GO:0004721	phosphoprotein phosphatase activity
0.38	GO:0008270	zinc ion binding

0.39	GO:0005694	chromosome
0.38	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.43	EC:4.1.1.17	GO:0004586
0.43	KEGG:R00670	GO:0004586

sp|P40809|RG84C_DROME
GTPase-activating protein RacGAP84C
Search

0.59	Rac GTPase-activating protein 1 (Fragment)

0.67	GO:0007266	Rho protein signal transduction
0.61	GO:0001745	compound eye morphogenesis
0.58	GO:0007283	spermatogenesis
0.57	GO:0043087	regulation of GTPase activity
0.57	GO:0051345	positive regulation of hydrolase activity
0.52	GO:0007525	somatic muscle development
0.51	GO:2000736	regulation of stem cell differentiation
0.51	GO:0048813	dendrite morphogenesis
0.50	GO:0000281	mitotic cytokinesis
0.49	GO:0001709	cell fate determination

0.58	GO:0005096	GTPase activator activity
0.57	GO:0017048	Rho GTPase binding
0.53	GO:0046872	metal ion binding
0.39	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0001565	phorbol ester receptor activity
0.33	GO:0046983	protein dimerization activity

0.52	GO:0055028	cortical microtubule
0.50	GO:0030496	midbody
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005819	spindle
0.41	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P40945|ARF2_DROME
ADP-ribosylation factor 2
Search

ARF4

0.66	ADP-ribosylation factor

0.53	GO:0006471	protein ADP-ribosylation
0.51	GO:0031584	activation of phospholipase D activity
0.51	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.50	GO:0060996	dendritic spine development
0.49	GO:0045176	apical protein localization
0.49	GO:0061512	protein localization to cilium
0.49	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.48	GO:2000377	regulation of reactive oxygen species metabolic process
0.48	GO:0007612	learning
0.46	GO:0043066	negative regulation of apoptotic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005154	epidermal growth factor receptor binding
0.47	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.36	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.33	GO:0003924	GTPase activity

0.49	GO:0032587	ruffle membrane
0.49	GO:0043197	dendritic spine
0.45	GO:0005622	intracellular
0.43	GO:0012505	endomembrane system
0.39	GO:0043227	membrane-bounded organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.35	GO:0031012	extracellular matrix
0.34	GO:0098793	presynapse
0.30	GO:0016021	integral component of membrane

0.47

EC:2.4.2.31

GO:0003956

sp|P40946|ARF3_DROME
ADP-ribosylation factor 3
Search

ARF6

0.67	ADP-ribosylation factor

0.54	GO:0035020	regulation of Rac protein signal transduction
0.54	GO:0036010	protein localization to endosome
0.54	GO:0033028	myeloid cell apoptotic process
0.53	GO:0001889	liver development
0.53	GO:0097178	ruffle assembly
0.53	GO:0097284	hepatocyte apoptotic process
0.52	GO:0051489	regulation of filopodium assembly
0.52	GO:0034394	protein localization to cell surface
0.51	GO:0032456	endocytic recycling
0.51	GO:0060998	regulation of dendritic spine development

0.66	GO:0005525	GTP binding
0.54	GO:0031996	thioesterase binding
0.51	GO:0047485	protein N-terminus binding
0.44	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.35	GO:0031681	G-protein beta-subunit binding
0.34	GO:0003924	GTPase activity
0.32	GO:0003723	RNA binding

0.56	GO:0032154	cleavage furrow
0.55	GO:0055037	recycling endosome
0.54	GO:0031527	filopodium membrane
0.54	GO:0090543	Flemming body
0.52	GO:0001726	ruffle
0.51	GO:0030139	endocytic vesicle
0.50	GO:0010008	endosome membrane
0.49	GO:0043209	myelin sheath
0.48	GO:0005938	cell cortex
0.44	GO:0005769	early endosome

0.44

EC:2.4.2.31

GO:0003956

sp|P41042|RS4_DROME
40S ribosomal protein S4
Search

0.65	40S ribosomal protein S4

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.35	GO:0044445	cytosolic part
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P41043|GSTS1_DROME
Glutathione S-transferase S1
Search

0.40	Glutathione-requiring prostaglandin D synthase

0.41	GO:0098869	cellular oxidant detoxification
0.38	GO:0006749	glutathione metabolic process
0.37	GO:0006979	response to oxidative stress
0.36	GO:0097354	prenylation
0.35	GO:0055114	oxidation-reduction process
0.34	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0007018	microtubule-based movement

0.50	GO:0016740	transferase activity
0.44	GO:0004602	glutathione peroxidase activity
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0003777	microtubule motor activity
0.32	GO:0016887	ATPase activity
0.32	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005861	troponin complex
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0030286	dynein complex

0.50

GO:0016740

sp|P41044|CAB32_DROME
Calbindin-32
Search

0.72

Calbindin

0.43	GO:1903035	negative regulation of response to wounding
0.41	GO:0055074	calcium ion homeostasis
0.40	GO:0072503	cellular divalent inorganic cation homeostasis
0.39	GO:0006875	cellular metal ion homeostasis
0.33	GO:0007165	signal transduction

0.70

GO:0005509

calcium ion binding

0.46	GO:0061175	type II terminal bouton
0.45	GO:0097467	type III terminal bouton
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P41046|CORTO_DROME
Centrosomal and chromosomal factor
Search

0.76	Centrosomal and chromosomal factor

0.80	GO:0045433	male courtship behavior, veined wing generated song production
0.77	GO:0007474	imaginal disc-derived wing vein specification
0.72	GO:0007076	mitotic chromosome condensation
0.51	GO:0060255	regulation of macromolecule metabolic process
0.45	GO:0006325	chromatin organization
0.44	GO:0031327	negative regulation of cellular biosynthetic process
0.44	GO:0045934	negative regulation of nucleobase-containing compound metabolic process
0.43	GO:0007018	microtubule-based movement
0.43	GO:0051301	cell division
0.40	GO:0007064	mitotic sister chromatid cohesion

0.68	GO:0003682	chromatin binding
0.66	GO:0042803	protein homodimerization activity
0.43	GO:0003777	microtubule motor activity
0.40	GO:0003676	nucleic acid binding
0.35	GO:0000175	3'-5'-exoribonuclease activity
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0008483	transaminase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016887	ATPase activity
0.33	GO:0008270	zinc ion binding

0.76	GO:0035102	PRC1 complex
0.74	GO:0035098	ESC/E(Z) complex
0.74	GO:0005700	polytene chromosome
0.69	GO:0005813	centrosome
0.44	GO:0005911	cell-cell junction
0.37	GO:0005737	cytoplasm
0.35	GO:0030015	CCR4-NOT core complex
0.35	GO:0016593	Cdc73/Paf1 complex
0.34	GO:0035770	ribonucleoprotein granule
0.34	GO:0030286	dynein complex

0.35

EC:3.1.13

GO:0000175

sp|P41073|PEP_DROME
Zinc finger protein on ecdysone puffs
Search

0.96	Zinc finger protein on ecdysone puffs

0.59	GO:0048024	regulation of mRNA splicing, via spliceosome
0.37	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0007034	vacuolar transport
0.32	GO:0080040	positive regulation of cellular response to phosphate starvation
0.32	GO:0042766	nucleosome mobilization
0.32	GO:0016584	nucleosome positioning
0.32	GO:0000722	telomere maintenance via recombination
0.32	GO:0060303	regulation of nucleosome density
0.32	GO:0043486	histone exchange
0.32	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress

0.57	GO:0003727	single-stranded RNA binding
0.53	GO:0003697	single-stranded DNA binding
0.51	GO:0046872	metal ion binding
0.32	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.32	GO:0070180	large ribosomal subunit rRNA binding
0.31	GO:0003743	translation initiation factor activity
0.31	GO:0003684	damaged DNA binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003924	GTPase activity

0.62	GO:0005703	polytene chromosome puff
0.38	GO:0071011	precatalytic spliceosome
0.38	GO:0071013	catalytic step 2 spliceosome
0.32	GO:0031011	Ino80 complex
0.32	GO:0000781	chromosome, telomeric region
0.32	GO:0005819	spindle
0.31	GO:0005874	microtubule
0.31	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|P41092|RL27A_DROME
60S ribosomal protein L27a
Search

0.45	60S ribosomal protein L27a (inferred by orthology to a human protein)

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.33	GO:0008299	isoprenoid biosynthetic process

0.63	GO:0003735	structural constituent of ribosome
0.38	GO:0003723	RNA binding
0.34	GO:0004452	isopentenyl-diphosphate delta-isomerase activity
0.32	GO:0016787	hydrolase activity

0.69	GO:0015934	large ribosomal subunit
0.43	GO:0022626	cytosolic ribosome
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:5.3.3.2	GO:0004452
0.34	KEGG:R01123	GO:0004452

sp|P41093|RL18A_DROME
60S ribosomal protein L18a
Search

0.10	Similar to Drosophila melanogaster RpL18A (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0097327	response to antineoplastic agent
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0033014	tetrapyrrole biosynthetic process
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0003723	RNA binding
0.34	GO:0003870	5-aminolevulinate synthase activity
0.33	GO:0005515	protein binding
0.33	GO:0030170	pyridoxal phosphate binding

0.61	GO:0005840	ribosome
0.43	GO:0005844	polysome
0.42	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34	EC:2.3.1.37	GO:0003870
0.34	KEGG:R00830	GO:0003870

sp|P41094|RS18_DROME
40S ribosomal protein S18
Search

RPS18

0.56	40S ribosomal protein S18 (inferred by orthology to a human protein)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0042254	ribosome biogenesis
0.32	GO:0006508	proteolysis

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005840	ribosome
0.41	GO:0000228	nuclear chromosome
0.41	GO:0005730	nucleolus
0.38	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.33

GO:0004222

sp|P41126|RL13_DROME
60S ribosomal protein L13
Search

0.65	Ribosomal protein L13

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.40	GO:0051726	regulation of cell cycle
0.32	GO:0006508	proteolysis

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.38	GO:0044445	cytosolic part
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0004222

sp|P41374|IF2A_DROME
Eukaryotic translation initiation factor 2 subunit 1
Search

0.71	Eukaryotic translation initiation factor

0.72	GO:0006413	translational initiation
0.46	GO:0032057	negative regulation of translational initiation in response to stress
0.44	GO:0034198	cellular response to amino acid starvation
0.43	GO:1901216	positive regulation of neuron death
0.43	GO:0034644	cellular response to UV
0.42	GO:0034976	response to endoplasmic reticulum stress
0.42	GO:0046777	protein autophosphorylation
0.38	GO:2000676	positive regulation of type B pancreatic cell apoptotic process
0.38	GO:0071287	cellular response to manganese ion
0.38	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity

0.73	GO:0003743	translation initiation factor activity
0.42	GO:0043022	ribosome binding
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0005515	protein binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005850	eukaryotic translation initiation factor 2 complex
0.46	GO:0005851	eukaryotic translation initiation factor 2B complex
0.42	GO:0010494	cytoplasmic stress granule
0.42	GO:0043614	multi-eIF complex
0.41	GO:0033290	eukaryotic 48S preinitiation complex
0.38	GO:0044207	translation initiation ternary complex
0.38	GO:0097451	glial limiting end-foot
0.37	GO:0005634	nucleus
0.37	GO:0005840	ribosome
0.35	GO:0005829	cytosol

sp|P41375|IF2B_DROME
Eukaryotic translation initiation factor 2 subunit 2
Search

0.78	Eukaryotic translation initiation factor

0.72	GO:0006413	translational initiation
0.52	GO:0016199	axon midline choice point recognition
0.48	GO:0034976	response to endoplasmic reticulum stress
0.38	GO:0016567	protein ubiquitination
0.35	GO:0002181	cytoplasmic translation
0.35	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0018022	peptidyl-lysine methylation
0.34	GO:0001522	pseudouridine synthesis
0.33	GO:0006396	RNA processing

0.73	GO:0003743	translation initiation factor activity
0.38	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0016279	protein-lysine N-methyltransferase activity
0.34	GO:0009982	pseudouridine synthase activity
0.33	GO:0046872	metal ion binding

0.38	GO:0005850	eukaryotic translation initiation factor 2 complex
0.36	GO:0043614	multi-eIF complex
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0005829	cytosol
0.34	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.34	EC:2.1.1	GO:0016279
0.38	KEGG:R03876	GO:0004842

sp|P41572|6PGD_DROME
6-phosphogluconate dehydrogenase, decarboxylating
Search

0.64	6-phosphogluconate dehydrogenase, decarboxylating

0.80	GO:0019521	D-gluconate metabolic process
0.73	GO:0006098	pentose-phosphate shunt
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0042593	glucose homeostasis

0.76

GO:0004616

phosphogluconate dehydrogenase (decarboxylating) activity

0.34

GO:0005739

mitochondrion

0.76

EC:1.1.1.44

GO:0004616

sp|P41596|DOPR1_DROME
Dopamine receptor 1
Search

0.96	Dopamine receptor I

0.71	GO:0007212	dopamine receptor signaling pathway
0.38	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.38	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration
0.38	GO:0019933	cAMP-mediated signaling
0.38	GO:0090328	regulation of olfactory learning
0.38	GO:1990834	response to odorant
0.38	GO:0071329	cellular response to sucrose stimulus
0.38	GO:0043052	thermotaxis
0.38	GO:0040040	thermosensory behavior
0.37	GO:0008355	olfactory learning

0.72	GO:0004952	dopamine neurotransmitter receptor activity
0.42	GO:0008227	G-protein coupled amine receptor activity
0.41	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.36	GO:0099589	serotonin receptor activity
0.36	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.34	GO:0004977	melanocortin receptor activity
0.34	GO:0051379	epinephrine binding
0.32	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.57	GO:0005887	integral component of plasma membrane
0.36	GO:0098793	presynapse
0.33	GO:0005622	intracellular
0.31	GO:0043227	membrane-bounded organelle

0.36

EC:2.7.10.2

GO:0004715

sp|P41894|DEI_DROME
Helix-loop-helix protein delilah
Search

0.91	Helix-loop-helix protein delilah

0.63	GO:0016203	muscle attachment
0.63	GO:0007474	imaginal disc-derived wing vein specification
0.63	GO:0033627	cell adhesion mediated by integrin
0.60	GO:0007498	mesoderm development
0.42	GO:0007525	somatic muscle development
0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated

0.68	GO:0046983	protein dimerization activity
0.63	GO:0043425	bHLH transcription factor binding
0.63	GO:0070888	E-box binding
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0005509	calcium ion binding

0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P41900|T2FB_DROME
General transcription factor IIF subunit 2
Search

0.91	General transcription factor IIF subunit 2

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.45	GO:0006368	transcription elongation from RNA polymerase II promoter
0.44	GO:0006413	translational initiation
0.41	GO:0031334	positive regulation of protein complex assembly
0.40	GO:0051254	positive regulation of RNA metabolic process
0.39	GO:0010557	positive regulation of macromolecule biosynthetic process
0.39	GO:0031328	positive regulation of cellular biosynthetic process

0.64	GO:0004386	helicase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0003677	DNA binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0001096	TFIIF-class transcription factor binding
0.44	GO:0003743	translation initiation factor activity
0.43	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.35	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
0.34	GO:0003826	alpha-ketoacid dehydrogenase activity

0.85	GO:0005674	transcription factor TFIIF complex
0.43	GO:0097550	transcriptional preinitiation complex
0.39	GO:0015630	microtubule cytoskeleton
0.33	GO:0005675	holo TFIIH complex
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.2.4

GO:0016624

sp|P41964|DMYC_DROME
Drosomycin
Search

0.97	Drosomycin

0.72	GO:0006952	defense response
0.71	GO:0009620	response to fungus
0.66	GO:0001562	response to protozoan
0.60	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.58	GO:0051715	cytolysis in other organism
0.54	GO:0009617	response to bacterium

0.63	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P42003|MAD_DROME
Protein mothers against dpp
Search

0.65	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0061352	cell chemotaxis involved in Malpighian tubule morphogenesis
0.51	GO:0048100	wing disc anterior/posterior pattern formation
0.51	GO:0071773	cellular response to BMP stimulus
0.50	GO:0007488	histoblast morphogenesis
0.50	GO:0035290	trunk segmentation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.48	GO:0001105	RNA polymerase II transcription coactivator activity
0.48	GO:0001102	RNA polymerase II activating transcription factor binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0022857	transmembrane transporter activity

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0016021	integral component of membrane

0.34	EC:3.2.1.113	GO:0004571
0.34	KEGG:R05982 KEGG:R06722	GO:0004571

sp|P42124|EZ_DROME
Histone-lysine N-methyltransferase E(z)
Search

0.77	Histone-lysine N-methyltransferase E

0.70	GO:0034968	histone lysine methylation
0.48	GO:1904772	response to tetrachloromethane
0.48	GO:0036333	hepatocyte homeostasis
0.47	GO:0035983	response to trichostatin A
0.47	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
0.47	GO:0070314	G1 to G0 transition
0.46	GO:0045814	negative regulation of gene expression, epigenetic
0.46	GO:0045605	negative regulation of epidermal cell differentiation
0.46	GO:0097421	liver regeneration
0.46	GO:0071236	cellular response to antibiotic

0.71	GO:0018024	histone-lysine N-methyltransferase activity
0.49	GO:1990841	promoter-specific chromatin binding
0.46	GO:0070878	primary miRNA binding
0.45	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.44	GO:0031490	chromatin DNA binding
0.44	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0043021	ribonucleoprotein complex binding
0.37	GO:0005515	protein binding
0.36	GO:0003700	DNA binding transcription factor activity

0.51	GO:0035098	ESC/E(Z) complex
0.46	GO:0045120	pronucleus
0.45	GO:0000790	nuclear chromatin
0.32	GO:0005737	cytoplasm

0.71

GO:0018024

sp|P42207|SEPT1_DROME
Septin-1
Search

0.66

Septin

0.61	GO:0051301	cell division
0.61	GO:0007049	cell cycle
0.45	GO:0002036	regulation of L-glutamate transport
0.43	GO:0007224	smoothened signaling pathway
0.43	GO:0043065	positive regulation of apoptotic process
0.42	GO:0060271	cilium assembly
0.40	GO:0032880	regulation of protein localization
0.39	GO:0050790	regulation of catalytic activity
0.35	GO:0007349	cellularization
0.34	GO:0007283	spermatogenesis

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0045296	cadherin binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0032947	protein complex scaffold activity
0.40	GO:0003924	GTPase activity
0.39	GO:0030234	enzyme regulator activity

0.50	GO:0031105	septin complex
0.44	GO:0097227	sperm annulus
0.44	GO:0060170	ciliary membrane
0.43	GO:0032391	photoreceptor connecting cilium
0.42	GO:0043209	myelin sheath
0.42	GO:0005930	axoneme
0.41	GO:0009986	cell surface
0.41	GO:0045202	synapse
0.37	GO:0005634	nucleus
0.36	GO:0030496	midbody

0.32

EC:2.7.11.19

GO:0004689

sp|P42271|TBG2_DROME
Tubulin gamma-2 chain
Search

0.70	Tubulin gamma chain

0.84	GO:0031122	cytoplasmic microtubule organization
0.81	GO:0007020	microtubule nucleation
0.49	GO:0000212	meiotic spindle organization
0.48	GO:0007312	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification
0.47	GO:0000280	nuclear division
0.46	GO:0098813	nuclear chromosome segregation
0.44	GO:0051225	spindle assembly
0.44	GO:0010457	centriole-centriole cohesion
0.42	GO:1903047	mitotic cell cycle process
0.41	GO:0051304	chromosome separation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0051011	microtubule minus-end binding
0.41	GO:0042802	identical protein binding
0.37	GO:0005200	structural constituent of cytoskeleton

0.84	GO:0000930	gamma-tubulin complex
0.73	GO:0005874	microtubule
0.51	GO:0005813	centrosome
0.51	GO:0005819	spindle
0.43	GO:0055037	recycling endosome
0.41	GO:0036064	ciliary basal body
0.41	GO:0097730	non-motile cilium
0.41	GO:0005814	centriole
0.41	GO:0045177	apical part of cell
0.41	GO:0031252	cell leading edge

sp|P42278|TRYT_DROME
Trypsin theta
Search

0.34	Midgut-specific serine protease 2

0.61	GO:0006508	proteolysis
0.37	GO:0007596	blood coagulation
0.37	GO:0007586	digestion
0.33	GO:0016192	vesicle-mediated transport
0.33	GO:0036211	protein modification process
0.33	GO:0032940	secretion by cell
0.32	GO:0098657	import into cell
0.32	GO:0044267	cellular protein metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005509	calcium ion binding
0.34	GO:0097655	serpin family protein binding
0.34	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.33	GO:0005044	scavenger receptor activity

0.41	GO:0005615	extracellular space
0.34	GO:0097180	serine protease inhibitor complex
0.34	GO:0005737	cytoplasm
0.33	GO:0099023	tethering complex
0.32	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P42279|TRYU_DROME
Trypsin eta
Search

0.39	Posterior midgut digestive trypsin

0.61	GO:0006508	proteolysis
0.41	GO:0007596	blood coagulation
0.34	GO:0007586	digestion
0.34	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006457	protein folding
0.33	GO:0050890	cognition

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005509	calcium ion binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0004177	aminopeptidase activity

0.39	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm
0.32	GO:0005887	integral component of plasma membrane

0.69

GO:0004252

sp|P42280|TRYZ_DROME
Trypsin zeta
Search

0.38	Digestive serine protease I

0.61	GO:0006508	proteolysis
0.45	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.44	GO:0007306	eggshell chorion assembly
0.42	GO:0007343	egg activation
0.39	GO:0051604	protein maturation
0.35	GO:0007596	blood coagulation
0.34	GO:0008063	Toll signaling pathway
0.33	GO:0032324	molybdopterin cofactor biosynthetic process
0.33	GO:0036211	protein modification process
0.33	GO:0006898	receptor-mediated endocytosis

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.33	GO:0005044	scavenger receptor activity

0.40	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm
0.33	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P42281|ACBP_DROME
Acyl-CoA-binding protein homolog
Search

0.57	Benzodiazepine receptor ligand

0.38	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.37	GO:0042049	cellular acyl-CoA homeostasis
0.36	GO:0021670	lateral ventricle development
0.36	GO:0001662	behavioral fear response
0.36	GO:0032228	regulation of synaptic transmission, GABAergic
0.36	GO:0060291	long-term synaptic potentiation
0.36	GO:0001942	hair follicle development
0.35	GO:0007611	learning or memory
0.35	GO:0006641	triglyceride metabolic process
0.35	GO:0006497	protein lipidation

0.82	GO:0000062	fatty-acyl-CoA binding
0.39	GO:0008289	lipid binding
0.35	GO:0046983	protein dimerization activity
0.35	GO:0030156	benzodiazepine receptor binding
0.34	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity

0.36	GO:0097038	perinuclear endoplasmic reticulum
0.35	GO:0008021	synaptic vesicle
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005576	extracellular region
0.34	GO:0034464	BBSome
0.34	GO:0043292	contractile fiber
0.33	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.3.1.97

GO:0004379

sp|P42282|TTKA_DROME
Protein tramtrack, alpha isoform
Search

TTK

0.73	Tramtrack, isoform G

0.61	GO:0048053	R1/R6 development
0.61	GO:0048750	compound eye corneal lens morphogenesis
0.61	GO:0048626	myoblast fate specification
0.60	GO:0045467	R7 cell development
0.59	GO:0042682	regulation of compound eye cone cell fate specification
0.59	GO:0035001	dorsal trunk growth, open tracheal system
0.58	GO:0042675	compound eye cone cell differentiation
0.58	GO:0060446	branching involved in open tracheal system development
0.58	GO:0007426	tracheal outgrowth, open tracheal system
0.58	GO:0035146	tube fusion

0.58	GO:0031208	POZ domain binding
0.56	GO:1990841	promoter-specific chromatin binding
0.56	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0042803	protein homodimerization activity
0.35	GO:0046872	metal ion binding

0.55	GO:0005700	polytene chromosome
0.53	GO:0017053	transcriptional repressor complex
0.47	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P42286|THR_DROME
Protein three rows
Search

0.82	GO:0007443	Malpighian tubule morphogenesis
0.73	GO:0000070	mitotic sister chromatid segregation
0.72	GO:0007502	digestive tract mesoderm development
0.69	GO:0007440	foregut morphogenesis
0.69	GO:0008258	head involution
0.66	GO:0007424	open tracheal system development
0.66	GO:0051298	centrosome duplication
0.65	GO:0007422	peripheral nervous system development
0.64	GO:0008406	gonad development
0.63	GO:0000281	mitotic cytokinesis

0.52

GO:0005515

protein binding

0.47	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P42287|GRK_DROME
Protein gurken
Search

0.84	GO:0008070	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded
0.78	GO:0016325	oocyte microtubule cytoskeleton organization
0.78	GO:0090110	cargo loading into COPII-coated vesicle
0.78	GO:0007310	oocyte dorsal/ventral axis specification
0.77	GO:0046843	dorsal appendage formation
0.75	GO:0007298	border follicle cell migration
0.53	GO:0008314	gurken signaling pathway
0.53	GO:0030714	anterior/posterior axis specification, follicular epithelium
0.50	GO:0030381	chorion-containing eggshell pattern formation
0.48	GO:0007314	oocyte anterior/posterior axis specification

0.49

GO:0005154

epidermal growth factor receptor binding

0.65	GO:0000139	Golgi membrane
0.51	GO:0005886	plasma membrane
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P42325|NCAH_DROME
Neurocalcin homolog
Search

0.75	Guanylyl cyclase-activating protein 2

0.36	GO:0048841	regulation of axon extension involved in axon guidance
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.35	GO:0016174	NAD(P)H oxidase activity
0.33	GO:0005515	protein binding

0.30

GO:0016020

membrane

0.35

EC:1.6.3.1

GO:0016174

sp|P42519|STAR_DROME
Protein Star
Search

0.74	GO:0038004	epidermal growth factor receptor ligand maturation
0.74	GO:0007421	stomatogastric nervous system development
0.73	GO:0046667	compound eye retinal cell programmed cell death
0.72	GO:0035225	determination of genital disc primordium
0.72	GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis
0.71	GO:0045467	R7 cell development
0.70	GO:0016318	ommatidial rotation
0.69	GO:0048865	stem cell fate commitment
0.68	GO:0048149	behavioral response to ethanol
0.66	GO:0007476	imaginal disc-derived wing morphogenesis

0.39	GO:0004402	histone acetyltransferase activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0003712	transcription cofactor activity
0.36	GO:0003676	nucleic acid binding
0.35	GO:0004672	protein kinase activity
0.34	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0046983	protein dimerization activity

0.68	GO:0097038	perinuclear endoplasmic reticulum
0.58	GO:0005794	Golgi apparatus
0.47	GO:0005886	plasma membrane
0.40	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0098588	bounding membrane of organelle
0.38	GO:0005634	nucleus
0.33	GO:0000786	nucleosome
0.32	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

0.39

GO:0004402

sp|P42570|PLU_DROME
DNA replication inhibitor plutonium
Search

PLU

0.97	DNA replication inhibitor plutonium

0.86	GO:0007343	egg activation
0.81	GO:0008156	negative regulation of DNA replication
0.44	GO:0007346	regulation of mitotic cell cycle
0.41	GO:0006260	DNA replication

0.80

GO:1902554

serine/threonine protein kinase complex

sp|P42787|CBPD_DROME
Carboxypeptidase D
Search

0.42	Zinc carboxypeptidase

0.61	GO:0006508	proteolysis
0.39	GO:0051604	protein maturation
0.39	GO:0007616	long-term memory
0.39	GO:0007476	imaginal disc-derived wing morphogenesis
0.38	GO:0030838	positive regulation of actin filament polymerization
0.37	GO:0001933	negative regulation of protein phosphorylation
0.37	GO:0006518	peptide metabolic process
0.33	GO:0016998	cell wall macromolecule catabolic process
0.33	GO:0009253	peptidoglycan catabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.47	GO:0004185	serine-type carboxypeptidase activity
0.38	GO:0042302	structural constituent of cuticle
0.33	GO:0003796	lysozyme activity

0.40	GO:0005615	extracellular space
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0012505	endomembrane system
0.34	GO:1903561	extracellular vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:3.4.17

GO:0004181

sp|P43125|RDGB_DROME
Protein retinal degeneration B
Search

0.80	Membrane-associated phosphatidylinositol transfer protein 3

0.78	GO:0015914	phospholipid transport
0.43	GO:0070588	calcium ion transmembrane transport
0.41	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.37	GO:0016059	deactivation of rhodopsin mediated signaling
0.36	GO:0016056	rhodopsin mediated signaling pathway
0.35	GO:0007601	visual perception
0.35	GO:0007608	sensory perception of smell
0.35	GO:0046488	phosphatidylinositol metabolic process

0.79	GO:0005548	phospholipid transporter activity
0.54	GO:0046872	metal ion binding
0.44	GO:0005388	calcium-transporting ATPase activity
0.36	GO:0070300	phosphatidic acid binding
0.35	GO:0035091	phosphatidylinositol binding
0.31	GO:0016740	transferase activity

0.45	GO:0005622	intracellular
0.36	GO:0016028	rhabdomere
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0012505	endomembrane system
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle

0.44

EC:3.6.3.8

GO:0005388

sp|P43248|MSH2_DROME
DNA mismatch repair protein spellchecker 1
Search

0.53	DNA mismatch repair protein spellchecker 1

0.75	GO:0006298	mismatch repair
0.50	GO:0043570	maintenance of DNA repeat elements
0.50	GO:0036297	interstrand cross-link repair
0.44	GO:0035822	gene conversion
0.41	GO:0045128	negative regulation of reciprocal meiotic recombination
0.40	GO:0022414	reproductive process
0.39	GO:0006312	mitotic recombination
0.39	GO:0000280	nuclear division
0.39	GO:0010165	response to X-ray
0.39	GO:0006301	postreplication repair

0.76	GO:0030983	mismatched DNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0000406	double-strand/single-strand DNA junction binding
0.41	GO:0000403	Y-form DNA binding
0.41	GO:0000400	four-way junction DNA binding
0.38	GO:0003684	damaged DNA binding
0.37	GO:0008094	DNA-dependent ATPase activity
0.32	GO:0008121	ubiquinol-cytochrome-c reductase activity

0.82	GO:0032300	mismatch repair complex
0.38	GO:0044428	nuclear part
0.34	GO:0005694	chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005886	plasma membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.32

EC:1.10.2.2

GO:0008121

sp|P43332|SNRPA_DROME
U1 small nuclear ribonucleoprotein A
Search

0.78	U2 small nuclear ribonucleoprotein B''

0.48	GO:0070868	heterochromatin organization involved in chromatin silencing
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.46	GO:0048477	oogenesis
0.38	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0019099	female germ-line sex determination
0.36	GO:0007539	primary sex determination, soma

0.55	GO:0003723	RNA binding
0.44	GO:0042802	identical protein binding

0.50	GO:0019013	viral nucleocapsid
0.48	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0120114	Sm-like protein family complex
0.43	GO:0044428	nuclear part
0.39	GO:0043234	protein complex
0.33	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

sp|P45437|COPB_DROME
Coatomer subunit beta
Search

0.62	Coatomer subunit beta

0.68	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.46	GO:0010883	regulation of lipid storage
0.43	GO:0048856	anatomical structure development
0.41	GO:0048869	cellular developmental process
0.38	GO:0016043	cellular component organization
0.38	GO:0032501	multicellular organismal process
0.35	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0045089	positive regulation of innate immune response
0.33	GO:0007165	signal transduction

0.61	GO:0005198	structural molecule activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0030126	COPI vesicle coat
0.73	GO:0000139	Golgi membrane
0.41	GO:0005829	cytosol
0.36	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P45447|E78C_DROME
Ecdysone-induced protein 78C
Search

EIP78C

0.68	Ecdysone-induced protein 78C

0.75	GO:0043401	steroid hormone mediated signaling pathway
0.61	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0051253	negative regulation of RNA metabolic process
0.39	GO:0010558	negative regulation of macromolecule biosynthetic process
0.39	GO:0031327	negative regulation of cellular biosynthetic process
0.38	GO:0006030	chitin metabolic process

0.76	GO:0003707	steroid hormone receptor activity
0.63	GO:0004879	nuclear receptor activity
0.59	GO:0043565	sequence-specific DNA binding
0.58	GO:0008270	zinc ion binding
0.45	GO:0005496	steroid binding
0.38	GO:0008061	chitin binding

0.61	GO:0005634	nucleus
0.37	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P45594|CADF_DROME
Cofilin/actin-depolymerizing factor homolog
Search

0.68	Actin depolymerization factor

0.84	GO:0030042	actin filament depolymerization
0.47	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.47	GO:0036011	imaginal disc-derived leg segmentation
0.47	GO:0042052	rhabdomere development
0.47	GO:0042067	establishment of ommatidial planar polarity
0.47	GO:0051299	centrosome separation
0.47	GO:0033206	meiotic cytokinesis
0.47	GO:0010591	regulation of lamellipodium assembly
0.47	GO:0016319	mushroom body development
0.47	GO:0030032	lamellipodium assembly

0.74

GO:0003779

actin binding

0.74	GO:0015629	actin cytoskeleton
0.35	GO:0016363	nuclear matrix
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P45843|SCRT_DROME
Protein scarlet
Search

0.53	ABC transporter scarlet

0.55	GO:0006856	eye pigment precursor transport
0.54	GO:0033060	ocellus pigmentation
0.54	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.54	GO:0006726	eye pigment biosynthetic process
0.48	GO:0044550	secondary metabolite biosynthetic process
0.44	GO:0055085	transmembrane transport
0.40	GO:0018130	heterocycle biosynthetic process
0.40	GO:1901362	organic cyclic compound biosynthetic process
0.40	GO:0019438	aromatic compound biosynthetic process
0.33	GO:0043547	positive regulation of GTPase activity

0.60	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005275	amine transmembrane transporter activity
0.37	GO:0015399	primary active transmembrane transporter activity
0.37	GO:0031409	pigment binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity

0.55	GO:0090740	integral component of pigment granule membrane
0.49	GO:0098793	presynapse
0.35	GO:0005886	plasma membrane
0.33	GO:0000786	nucleosome
0.33	GO:0005634	nucleus

0.60

GO:0016887

sp|P45884|ATTA_DROME
Attacin-A
Search

0.95	Antimicrobial peptide Attacin B

0.78	GO:0042742	defense response to bacterium
0.40	GO:0019730	antimicrobial humoral response
0.39	GO:0045087	innate immune response
0.30	GO:0055093	response to hyperoxia

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P45888|ARP2_DROME
Actin-related protein 2
Search

0.53	Actin-related protein ARP2/3 complex subunit ARP2

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.48	GO:0016344	meiotic chromosome movement towards spindle pole
0.46	GO:0033206	meiotic cytokinesis
0.46	GO:0071346	cellular response to interferon-gamma
0.45	GO:0008356	asymmetric cell division
0.45	GO:0051653	spindle localization
0.45	GO:0072553	terminal button organization
0.44	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.44	GO:0016482	cytosolic transport
0.44	GO:0007163	establishment or maintenance of cell polarity

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003779	actin binding
0.44	GO:0005200	structural constituent of cytoskeleton
0.43	GO:0032403	protein complex binding

0.80	GO:0005885	Arp2/3 protein complex
0.47	GO:0030478	actin cap
0.41	GO:0005829	cytosol
0.38	GO:0042995	cell projection
0.37	GO:0061825	podosome core
0.36	GO:0014069	postsynaptic density
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031252	cell leading edge
0.35	GO:1904813	ficolin-1-rich granule lumen

sp|P45889|ACTZ_DROME
Actin-related protein 1
Search

0.49	Alpha-centractin

0.46	GO:0019896	axonal transport of mitochondrion
0.46	GO:0008090	retrograde axonal transport
0.46	GO:0008089	anterograde axonal transport
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0000278	mitotic cell cycle
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0044839	cell cycle G2/M phase transition
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0007283	spermatogenesis

0.50	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0005515	protein binding

0.82	GO:0005869	dynactin complex
0.49	GO:0005813	centrosome
0.47	GO:0099568	cytoplasmic region
0.44	GO:0033267	axon part
0.43	GO:0043209	myelin sheath
0.37	GO:0071944	cell periphery
0.37	GO:0070062	extracellular exosome
0.35	GO:0005680	anaphase-promoting complex
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0002177	manchette

sp|P45890|ARP6_DROME
Actin-related protein 6
Search

0.50

Actin

0.78	GO:0006338	chromatin remodeling
0.41	GO:0006348	chromatin silencing at telomere
0.40	GO:0034728	nucleosome organization
0.37	GO:0070828	heterochromatin organization
0.36	GO:0097354	prenylation
0.34	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process
0.32	GO:0043632	modification-dependent macromolecule catabolic process
0.32	GO:0030163	protein catabolic process
0.32	GO:0006508	proteolysis

0.36	GO:0003682	chromatin binding
0.36	GO:0008318	protein prenyltransferase activity
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003676	nucleic acid binding

0.61	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.40	GO:0000781	chromosome, telomeric region
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:1904949	ATPase complex
0.35	GO:0005856	cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

EC:2.5.1

GO:0008318

sp|P45891|ACTY_DROME
Actin-like protein 53D
Search

0.51	Cytosolic actin

0.42	GO:0048768	root hair cell tip growth
0.39	GO:0010114	response to red light
0.39	GO:0010218	response to far red light
0.39	GO:0009644	response to high light intensity
0.39	GO:0009735	response to cytokinin
0.38	GO:0007010	cytoskeleton organization
0.38	GO:0009651	response to salt stress
0.36	GO:0036213	contractile ring contraction
0.36	GO:0000011	vacuole inheritance
0.36	GO:1902407	assembly of actomyosin apparatus involved in mitotic cytokinesis

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005200	structural constituent of cytoskeleton
0.37	GO:0003729	mRNA binding
0.36	GO:0005507	copper ion binding
0.36	GO:0004402	histone acetyltransferase activity
0.35	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity
0.35	GO:0005515	protein binding

0.46	GO:0005856	cytoskeleton
0.40	GO:0044446	intracellular organelle part
0.39	GO:0043234	protein complex
0.38	GO:0009506	plasmodesma
0.37	GO:0099512	supramolecular fiber
0.37	GO:0005829	cytosol
0.37	GO:0005773	vacuole
0.36	GO:0005628	prospore membrane
0.36	GO:0070938	contractile ring
0.36	GO:0005634	nucleus

0.36

GO:0004402

sp|P45975|SUV39_DROME
Histone-lysine N-methyltransferase Su(var)3-9
Search

0.62	Eukaryotic translation initiation factor 2 subunit 3

0.69	GO:0034968	histone lysine methylation
0.60	GO:2001229	negative regulation of response to gamma radiation
0.58	GO:0048132	female germ-line stem cell asymmetric division
0.58	GO:0061647	histone H3-K9 modification
0.57	GO:0031507	heterochromatin assembly
0.57	GO:0070868	heterochromatin organization involved in chromatin silencing
0.50	GO:0006413	translational initiation
0.50	GO:0006306	DNA methylation
0.43	GO:0030702	chromatin silencing at centromere
0.42	GO:0006348	chromatin silencing at telomere

0.70	GO:0018024	histone-lysine N-methyltransferase activity
0.59	GO:0003924	GTPase activity
0.57	GO:0032550	purine ribonucleoside binding
0.57	GO:0019001	guanyl nucleotide binding
0.56	GO:0008270	zinc ion binding
0.51	GO:0003743	translation initiation factor activity
0.48	GO:0032555	purine ribonucleotide binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005515	protein binding
0.34	GO:0000049	tRNA binding

0.60	GO:0005694	chromosome
0.55	GO:0005634	nucleus
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005850	eukaryotic translation initiation factor 2 complex
0.36	GO:0043614	multi-eIF complex
0.36	GO:0016282	eukaryotic 43S preinitiation complex
0.35	GO:0033290	eukaryotic 48S preinitiation complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0018024

sp|P46150|MOEH_DROME
Moesin/ezrin/radixin homolog 1
Search

0.78	Ezrin-moesin-radixin

0.42	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.36	GO:0016336	establishment or maintenance of polarity of larval imaginal disc epithelium
0.36	GO:0045313	rhabdomere membrane biogenesis
0.36	GO:0016057	regulation of membrane potential in photoreceptor cell
0.36	GO:0110028	positive regulation of mitotic spindle organization
0.36	GO:0007318	pole plasm protein localization
0.36	GO:0045433	male courtship behavior, veined wing generated song production
0.36	GO:0072499	photoreceptor cell axon guidance
0.36	GO:0035149	lumen formation, open tracheal system
0.36	GO:0032888	regulation of mitotic spindle elongation

0.73	GO:0003779	actin binding
0.36	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0008017	microtubule binding

0.69	GO:0005856	cytoskeleton
0.40	GO:0005912	adherens junction
0.36	GO:0035003	subapical complex
0.36	GO:0045169	fusome
0.36	GO:0005703	polytene chromosome puff
0.36	GO:0032154	cleavage furrow
0.36	GO:0035327	transcriptionally active chromatin
0.35	GO:0016324	apical plasma membrane
0.35	GO:0005938	cell cortex
0.34	GO:0099512	supramolecular fiber

sp|P46222|RL11_DROME
60S ribosomal protein L11
Search

0.63	Ribosomal protein L11

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0000027	ribosomal large subunit assembly
0.35	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.35	GO:2000435	negative regulation of protein neddylation
0.35	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.34	GO:1901796	regulation of signal transduction by p53 class mediator

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0005549	odorant binding
0.35	GO:0004984	olfactory receptor activity
0.35	GO:0019843	rRNA binding
0.35	GO:1990948	ubiquitin ligase inhibitor activity
0.34	GO:0031625	ubiquitin protein ligase binding

0.61	GO:0005840	ribosome
0.45	GO:0005703	polytene chromosome puff
0.42	GO:0005730	nucleolus
0.41	GO:0000228	nuclear chromosome
0.36	GO:0044445	cytosolic part
0.34	GO:0005844	polysome
0.33	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P46223|RL7A_DROME
60S ribosomal protein L7a
Search

RPL7A

0.51	Ribosomal protein L7Ae

0.65	GO:0042254	ribosome biogenesis
0.36	GO:0016072	rRNA metabolic process
0.35	GO:0034470	ncRNA processing
0.35	GO:0006412	translation

0.35	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.61	GO:1990904	ribonucleoprotein complex
0.54	GO:0043232	intracellular non-membrane-bounded organelle
0.50	GO:0044444	cytoplasmic part
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P46415|ADHX_DROME
Alcohol dehydrogenase class-3
Search

0.59	S-(Hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase

0.80	GO:0006069	ethanol oxidation
0.48	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation
0.47	GO:0008542	visual learning
0.41	GO:0018119	peptidyl-cysteine S-nitrosylation
0.41	GO:0003016	respiratory system process
0.41	GO:0045777	positive regulation of blood pressure
0.40	GO:0001523	retinoid metabolic process
0.40	GO:0051409	response to nitrosative stress
0.40	GO:0032496	response to lipopolysaccharide
0.40	GO:0051775	response to redox state

0.80	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.63	GO:0008270	zinc ion binding
0.52	GO:0004552	octanol dehydrogenase activity
0.50	GO:0080007	S-nitrosoglutathione reductase activity
0.48	GO:0004022	alcohol dehydrogenase (NAD) activity
0.41	GO:0018467	formaldehyde dehydrogenase activity
0.40	GO:0005504	fatty acid binding
0.38	GO:0042803	protein homodimerization activity
0.34	GO:0008083	growth factor activity
0.33	GO:0008173	RNA methyltransferase activity

0.36	GO:0005739	mitochondrion
0.35	GO:0005730	nucleolus
0.33	GO:0005576	extracellular region

0.80	EC:1.1.1.284	GO:0051903
0.80	KEGG:R06983 KEGG:R07140	GO:0051903

sp|P46461|NSF1_DROME
Vesicle-fusing ATPase 1
Search

0.72	N-ethylmaleimide-sensitive factor

0.53	GO:0007274	neuromuscular synaptic transmission
0.48	GO:0035494	SNARE complex disassembly
0.48	GO:0090160	Golgi to lysosome transport
0.48	GO:1900073	regulation of neuromuscular synaptic transmission
0.48	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.48	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane
0.48	GO:0070050	neuron cellular homeostasis
0.46	GO:0060439	trachea morphogenesis
0.46	GO:0007030	Golgi organization
0.46	GO:0008582	regulation of synaptic growth at neuromuscular junction

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016887	ATPase activity
0.35	GO:0052689	carboxylic ester hydrolase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.50	GO:0098527	neuromuscular junction of somatic muscle
0.47	GO:0043195	terminal bouton
0.45	GO:0008021	synaptic vesicle
0.42	GO:0005829	cytosol
0.34	GO:0005576	extracellular region
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.36	EC:3.6.1.3	GO:0016887
0.35	KEGG:R00630	GO:0052689

sp|P46824|KLC_DROME
Kinesin light chain
Search

KLC

0.67	Kinesin light chain

0.51	GO:0046843	dorsal appendage formation
0.46	GO:0007018	microtubule-based movement
0.38	GO:0040038	polar body extrusion after meiotic divisions
0.38	GO:0051295	establishment of meiotic spindle localization
0.38	GO:0048675	axon extension
0.38	GO:0002119	nematode larval development
0.37	GO:0007097	nuclear migration
0.37	GO:0097480	establishment of synaptic vesicle localization
0.37	GO:0099003	vesicle-mediated transport in synapse
0.37	GO:0030705	cytoskeleton-dependent intracellular transport

0.75	GO:0003777	microtubule motor activity
0.37	GO:0019894	kinesin binding
0.33	GO:0003729	mRNA binding

0.81	GO:0005871	kinesin complex
0.36	GO:0005635	nuclear envelope
0.36	GO:0045202	synapse
0.35	GO:0005874	microtubule
0.33	GO:0005685	U1 snRNP
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P46863|KL61_DROME
Kinesin-like protein Klp61F
Search

KLP61F

0.97	Bipolar kinesin

0.74	GO:0007018	microtubule-based movement
0.55	GO:0007100	mitotic centrosome separation
0.55	GO:0045478	fusome organization
0.54	GO:0007052	mitotic spindle organization
0.54	GO:0048085	adult chitin-containing cuticle pigmentation
0.53	GO:0042998	positive regulation of Golgi to plasma membrane protein transport
0.52	GO:0051289	protein homotetramerization
0.51	GO:0001578	microtubule bundle formation
0.51	GO:0007030	Golgi organization
0.46	GO:0009306	protein secretion

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042623	ATPase activity, coupled
0.38	GO:0019901	protein kinase binding
0.37	GO:0032403	protein complex binding
0.33	GO:0005509	calcium ion binding

0.55	GO:0005874	microtubule
0.53	GO:0045169	fusome
0.53	GO:0005818	aster
0.53	GO:0097431	mitotic spindle pole
0.52	GO:0005871	kinesin complex
0.49	GO:0005813	centrosome
0.46	GO:0005794	Golgi apparatus
0.46	GO:0005783	endoplasmic reticulum
0.42	GO:0005634	nucleus
0.36	GO:0005829	cytosol

sp|P46867|KLP68_DROME
Kinesin-like protein Klp68D
Search

0.38	Eukaryotic translation initiation factor 3 subunit K

0.74	GO:0007018	microtubule-based movement
0.53	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.52	GO:0030705	cytoskeleton-dependent intracellular transport
0.48	GO:0007608	sensory perception of smell
0.41	GO:0036334	epidermal stem cell homeostasis
0.41	GO:0060271	cilium assembly
0.40	GO:0010457	centriole-centriole cohesion
0.40	GO:0034454	microtubule anchoring at centrosome
0.40	GO:0022008	neurogenesis
0.40	GO:0021542	dentate gyrus development

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016887	ATPase activity
0.35	GO:0043022	ribosome binding
0.35	GO:0003743	translation initiation factor activity

0.72	GO:0005874	microtubule
0.53	GO:1904115	axon cytoplasm
0.52	GO:0005875	microtubule associated complex
0.39	GO:0032391	photoreceptor connecting cilium
0.39	GO:0005814	centriole
0.39	GO:0030990	intraciliary transport particle
0.38	GO:0031514	motile cilium
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.35	GO:0033290	eukaryotic 48S preinitiation complex
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex

0.37

GO:0016887

sp|P47825|TAF4_DROME
Transcription initiation factor TFIID subunit 4
Search

TAF4

0.60	Transcription initiation factor TFIID subunit 4

0.69	GO:0006352	DNA-templated transcription, initiation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006413	translational initiation
0.38	GO:0065004	protein-DNA complex assembly
0.38	GO:0006366	transcription by RNA polymerase II
0.38	GO:0051254	positive regulation of RNA metabolic process
0.38	GO:0010557	positive regulation of macromolecule biosynthetic process
0.38	GO:0031328	positive regulation of cellular biosynthetic process

0.74	GO:0046982	protein heterodimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0003743	translation initiation factor activity
0.40	GO:0001092	TFIIA-class transcription factor binding
0.39	GO:0003713	transcription coactivator activity
0.35	GO:0003677	DNA binding

0.80	GO:0005669	transcription factor TFIID complex
0.34	GO:0070461	SAGA-type complex
0.30	GO:0016020	membrane

sp|P47938|THIO1_DROME
Thioredoxin-1
Search

0.41	Thioredoxin

0.73	GO:0006662	glycerol ether metabolic process
0.69	GO:0045454	cell redox homeostasis
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0007143	female meiotic nuclear division
0.44	GO:0060322	head development
0.44	GO:0098869	cellular oxidant detoxification
0.39	GO:0034599	cellular response to oxidative stress
0.34	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress
0.34	GO:0008340	determination of adult lifespan
0.34	GO:0043433	negative regulation of DNA binding transcription factor activity

0.70	GO:0015035	protein disulfide oxidoreductase activity
0.44	GO:0016209	antioxidant activity
0.41	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
0.39	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.35	GO:0016853	isomerase activity
0.33	GO:0019239	deaminase activity
0.33	GO:0005509	calcium ion binding

0.39	GO:0005634	nucleus
0.34	GO:0097730	non-motile cilium
0.34	GO:0005737	cytoplasm
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.33	GO:0043233	organelle lumen
0.32	GO:0005886	plasma membrane
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.41

EC:1.8.1

GO:0016668

sp|P47947|TNNC1_DROME
Troponin C, isoform 1
Search

0.75	Troponin C type IIIa

0.33	GO:0001172	transcription, RNA-templated
0.33	GO:0039694	viral RNA genome replication

0.70	GO:0005509	calcium ion binding
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity

0.30

GO:0031224

intrinsic component of membrane

0.33

EC:2.7.7.48

GO:0003968

sp|P47948|TNNC2_DROME
Troponin C, isoform 2
Search

0.53	Troponin C type Ib

0.32	GO:0055114	oxidation-reduction process
0.32	GO:0055085	transmembrane transport

0.70	GO:0005509	calcium ion binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.30

GO:0044425

membrane part

0.34

GO:0032440

sp|P47949|TNNC3_DROME
Troponin C, isoform 3
Search

0.51	Troponin C type Ia

0.32	GO:0055114	oxidation-reduction process
0.32	GO:0055085	transmembrane transport

0.70	GO:0005509	calcium ion binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.30

GO:0044425

membrane part

0.34

GO:0032440

sp|P47980|TIS11_DROME
Protein TIS11
Search

0.71	Butyrate response factor 2

0.58	GO:0061158	3'-UTR-mediated mRNA destabilization
0.55	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.53	GO:0016246	RNA interference
0.39	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.39	GO:0070371	ERK1 and ERK2 cascade
0.39	GO:0045577	regulation of B cell differentiation
0.39	GO:0071364	cellular response to epidermal growth factor stimulus
0.39	GO:0071385	cellular response to glucocorticoid stimulus
0.39	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.39	GO:0045598	regulation of fat cell differentiation

0.57	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.54	GO:0046872	metal ion binding
0.36	GO:0071889	14-3-3 protein binding
0.35	GO:0003677	DNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding

0.40	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.35	GO:0000932	P-body
0.30	GO:0016020	membrane

sp|P48148|RHO1_DROME
Ras-like GTP-binding protein Rho1
Search

0.59	ADP ribosylation factor

0.76	GO:0007264	small GTPase mediated signal transduction
0.48	GO:0042060	wound healing
0.48	GO:0002009	morphogenesis of an epithelium
0.47	GO:0016477	cell migration
0.47	GO:0035026	leading edge cell differentiation
0.47	GO:0030589	pseudocleavage involved in syncytial blastoderm formation
0.47	GO:1904059	regulation of locomotor rhythm
0.47	GO:0007377	germ-band extension
0.46	GO:0071896	protein localization to adherens junction
0.46	GO:0070593	dendrite self-avoidance

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.43	GO:0019900	kinase binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0003779	actin binding

0.47	GO:0070451	cell hair
0.45	GO:0045179	apical cortex
0.45	GO:0044291	cell-cell contact zone
0.44	GO:0016324	apical plasma membrane
0.33	GO:0005856	cytoskeleton
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.34

EC:1.2.1

GO:0016620

sp|P48149|RS15A_DROME
40S ribosomal protein S15Aa
Search

RPS15A

0.52	Ribosomal protein S15

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006399	tRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0000213	tRNA-intron endonuclease activity
0.34	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.33	GO:0000287	magnesium ion binding
0.32	GO:0003676	nucleic acid binding

0.61	GO:0005840	ribosome
0.38	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.27.9

GO:0000213

sp|P48159|RL23_DROME
60S ribosomal protein L23
Search

RPL23

0.55	Ribosomal protein L23

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0017022	myosin binding
0.37	GO:0070180	large ribosomal subunit rRNA binding

0.61	GO:0005840	ribosome
0.36	GO:0044445	cytosolic part
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P48375|FKB12_DROME
12 kDa FK506-binding protein
Search

0.44	Peptidylprolyl isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.46	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.46	GO:0060347	heart trabecula formation
0.46	GO:0031000	response to caffeine
0.45	GO:0042098	T cell proliferation
0.45	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.44	GO:0051209	release of sequestered calcium ion into cytosol
0.44	GO:0006936	muscle contraction
0.43	GO:1990000	amyloid fibril formation
0.43	GO:0007183	SMAD protein complex assembly

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.48	GO:0005528	FK506 binding
0.45	GO:0044325	ion channel binding
0.43	GO:0048185	activin binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0046332	SMAD binding
0.37	GO:0034713	type I transforming growth factor beta receptor binding
0.37	GO:0019855	calcium channel inhibitor activity
0.37	GO:0030544	Hsp70 protein binding
0.35	GO:0019899	enzyme binding

0.46	GO:0033017	sarcoplasmic reticulum membrane
0.42	GO:0030018	Z disc
0.39	GO:0005829	cytosol
0.39	GO:0014802	terminal cisterna
0.37	GO:0005891	voltage-gated calcium channel complex
0.37	GO:0031312	extrinsic component of organelle membrane
0.37	GO:0043679	axon terminus
0.37	GO:0098562	cytoplasmic side of membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0043204	perikaryon

0.72

EC:5.2.1.8

GO:0003755

sp|P48423|GAP1_DROME
GTPase-activating protein
Search

0.50	GTPase-activating protein 1

0.75	GO:0043087	regulation of GTPase activity
0.72	GO:0051345	positive regulation of hydrolase activity
0.62	GO:0035556	intracellular signal transduction
0.59	GO:0046580	negative regulation of Ras protein signal transduction
0.55	GO:0045678	positive regulation of R7 cell differentiation
0.54	GO:0007426	tracheal outgrowth, open tracheal system
0.51	GO:0007476	imaginal disc-derived wing morphogenesis
0.43	GO:0051209	release of sequestered calcium ion into cytosol
0.41	GO:0043363	nucleate erythrocyte differentiation
0.40	GO:0002574	thrombocyte differentiation

0.74	GO:0005096	GTPase activator activity
0.43	GO:0015278	calcium-release channel activity
0.36	GO:0016849	phosphorus-oxygen lyase activity
0.34	GO:0046872	metal ion binding

0.46	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.45	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.36

EC:4.6

GO:0016849

sp|P48451|CANB1_DROME
Calcineurin subunit B type 1
Search

0.71	Calcineurin subunit B type

0.50	GO:0030431	sleep
0.46	GO:0030241	skeletal muscle myosin thick filament assembly
0.44	GO:0045214	sarcomere organization
0.42	GO:0051321	meiotic cell cycle
0.39	GO:0051531	NFAT protein import into nucleus
0.39	GO:0006470	protein dephosphorylation
0.39	GO:0033173	calcineurin-NFAT signaling cascade
0.38	GO:0060487	lung epithelial cell differentiation
0.38	GO:0001569	branching involved in blood vessel morphogenesis
0.38	GO:0022011	myelination in peripheral nervous system

0.70	GO:0005509	calcium ion binding
0.38	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity
0.37	GO:0016018	cyclosporin A binding
0.36	GO:0005515	protein binding
0.34	GO:0003684	damaged DNA binding

0.39	GO:0005955	calcineurin complex
0.38	GO:0042383	sarcolemma
0.36	GO:0008021	synaptic vesicle
0.34	GO:0000796	condensin complex
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.38

GO:0004721

sp|P48456|PP2B1_DROME
Serine/threonine-protein phosphatase 2B catalytic subunit 1
Search

PPP3CA

0.50	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.55	GO:1905205	positive regulation of connective tissue replacement
0.54	GO:1903244	positive regulation of cardiac muscle hypertrophy in response to stress
0.54	GO:0033173	calcineurin-NFAT signaling cascade
0.54	GO:0051533	positive regulation of NFAT protein import into nucleus
0.54	GO:0097366	response to bronchodilator
0.54	GO:0014883	transition between fast and slow fiber
0.53	GO:0035562	negative regulation of chromatin binding
0.53	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA
0.53	GO:0050774	negative regulation of dendrite morphogenesis

0.72	GO:0004721	phosphoprotein phosphatase activity
0.54	GO:0016018	cyclosporin A binding
0.50	GO:0005516	calmodulin binding
0.46	GO:0019899	enzyme binding
0.45	GO:0046983	protein dimerization activity
0.35	GO:0046872	metal ion binding
0.31	GO:0046873	metal ion transmembrane transporter activity
0.31	GO:0003676	nucleic acid binding

0.55	GO:0005955	calcineurin complex
0.51	GO:0030018	Z disc
0.48	GO:0044456	synapse part
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0042383	sarcolemma
0.36	GO:0031982	vesicle
0.36	GO:0097458	neuron part
0.35	GO:0043230	extracellular organelle

0.72

GO:0004721

sp|P48461|PP11_DROME
Serine/threonine-protein phosphatase alpha-1 isoform
Search

0.52	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.46	GO:0043153	entrainment of circadian clock by photoperiod
0.45	GO:0007623	circadian rhythm
0.45	GO:0032501	multicellular organismal process
0.44	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.44	GO:0046822	regulation of nucleocytoplasmic transport
0.44	GO:0019953	sexual reproduction
0.41	GO:0042048	olfactory behavior
0.41	GO:0007080	mitotic metaphase plate congression
0.40	GO:0051225	spindle assembly

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.53	GO:0046872	metal ion binding
0.45	GO:0047485	protein N-terminus binding
0.43	GO:0019901	protein kinase binding
0.36	GO:0005521	lamin binding
0.36	GO:0008157	protein phosphatase 1 binding
0.36	GO:0008022	protein C-terminus binding
0.35	GO:0019904	protein domain specific binding
0.35	GO:0032403	protein complex binding
0.33	GO:0003723	RNA binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.58	GO:0072357	PTW/PP1 phosphatase complex
0.44	GO:0000784	nuclear chromosome, telomeric region
0.43	GO:0005741	mitochondrial outer membrane
0.42	GO:0005730	nucleolus
0.41	GO:0005700	polytene chromosome
0.39	GO:0097610	cell surface furrow
0.39	GO:0030496	midbody
0.39	GO:0043234	protein complex
0.39	GO:0032155	cell division site part

sp|P48462|PP1B_DROME
Serine/threonine-protein phosphatase beta isoform
Search

0.53	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.36	GO:0007623	circadian rhythm
0.36	GO:1904886	beta-catenin destruction complex disassembly
0.36	GO:0007312	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification
0.36	GO:0007301	female germline ring canal formation
0.35	GO:0046329	negative regulation of JNK cascade
0.35	GO:0031991	regulation of actomyosin contractile ring contraction
0.35	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.35	GO:0007476	imaginal disc-derived wing morphogenesis
0.35	GO:0007498	mesoderm development

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.54	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.65	GO:0072357	PTW/PP1 phosphatase complex
0.35	GO:0020036	Maurer's cleft
0.34	GO:0005730	nucleolus
0.34	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P48554|RAC2_DROME
Ras-related protein Rac2
Search

0.60	ADP ribosylation factor

0.77	GO:0007264	small GTPase mediated signal transduction
0.51	GO:0007394	dorsal closure, elongation of leading edge cells
0.50	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
0.50	GO:0035099	hemocyte migration
0.50	GO:0007426	tracheal outgrowth, open tracheal system
0.50	GO:0007390	germ-band shortening
0.50	GO:0035011	melanotic encapsulation of foreign target
0.50	GO:0034334	adherens junction maintenance
0.49	GO:0008258	head involution
0.49	GO:0046843	dorsal appendage formation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.46	GO:0019901	protein kinase binding
0.42	GO:0032794	GTPase activating protein binding
0.36	GO:0004003	ATP-dependent DNA helicase activity
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0008144	drug binding

0.45	GO:0005622	intracellular
0.42	GO:0016028	rhabdomere
0.41	GO:0001726	ruffle
0.39	GO:0019897	extrinsic component of plasma membrane
0.38	GO:0099512	supramolecular fiber
0.36	GO:0043234	protein complex
0.36	GO:0043228	non-membrane-bounded organelle
0.36	GO:0044422	organelle part

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P48555|RALA_DROME
Ras-related protein Ral-a
Search

RALA

0.73	Putative rab subfamily protein of small gtpase

0.64	GO:0007265	Ras protein signal transduction
0.46	GO:0002009	morphogenesis of an epithelium
0.46	GO:0048056	R3/R4 cell differentiation
0.45	GO:0001752	compound eye photoreceptor fate commitment
0.45	GO:0046329	negative regulation of JNK cascade
0.44	GO:0007298	border follicle cell migration
0.44	GO:0051665	membrane raft localization
0.44	GO:0007164	establishment of tissue polarity
0.44	GO:0008593	regulation of Notch signaling pathway
0.43	GO:0051491	positive regulation of filopodium assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.44	GO:0030165	PDZ domain binding
0.42	GO:0051117	ATPase binding
0.42	GO:0017022	myosin binding
0.41	GO:0031625	ubiquitin protein ligase binding

0.47	GO:0005886	plasma membrane
0.44	GO:0097610	cell surface furrow
0.43	GO:0032155	cell division site part
0.42	GO:0043209	myelin sheath
0.41	GO:0030139	endocytic vesicle
0.39	GO:0090543	Flemming body
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome
0.34	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0005829	cytosol

0.34

GO:0004713

sp|P48588|RS25_DROME
40S ribosomal protein S25
Search

0.69	Small ribosomal subunit S25

0.36	GO:0006811	ion transport
0.35	GO:0002181	cytoplasmic translation

0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0032553	ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003735	structural constituent of ribosome

0.60	GO:0005840	ribosome
0.41	GO:0005921	gap junction
0.35	GO:0005886	plasma membrane
0.35	GO:0044445	cytosolic part
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P48591|RIR1_DROME
Ribonucleoside-diphosphate reductase large subunit
Search

0.55	Ribonucleoside-diphosphate reductase large subunit

0.66	GO:0006260	DNA replication
0.53	GO:0055114	oxidation-reduction process
0.45	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.45	GO:0042246	tissue regeneration
0.38	GO:0051290	protein heterotetramerization
0.37	GO:0009263	deoxyribonucleotide biosynthetic process

0.77	GO:0061731	ribonucleoside-diphosphate reductase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0097718	disordered domain specific binding
0.36	GO:0042802	identical protein binding

0.37	GO:0005971	ribonucleoside-diphosphate reductase complex
0.30	GO:0016021	integral component of membrane

sp|P48592|RIR2_DROME
Ribonucleoside-diphosphate reductase subunit M2
Search

RRM2

0.64	Ribonucleoside diphosphate reductase small subunit

0.74	GO:0009263	deoxyribonucleotide biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0042981	regulation of apoptotic process
0.46	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.45	GO:0006264	mitochondrial DNA replication
0.44	GO:1901797	negative regulation of signal transduction by p53 class mediator
0.44	GO:0043068	positive regulation of programmed cell death
0.44	GO:0003014	renal system process
0.43	GO:0051290	protein heterotetramerization
0.43	GO:0001822	kidney development

0.54	GO:0016491	oxidoreductase activity
0.44	GO:0046872	metal ion binding
0.40	GO:0042803	protein homodimerization activity

0.48	GO:0005971	ribonucleoside-diphosphate reductase complex
0.40	GO:0005654	nucleoplasm
0.38	GO:0005739	mitochondrion
0.34	GO:0070062	extracellular exosome
0.34	GO:0005635	nuclear envelope
0.30	GO:0016021	integral component of membrane

0.54

GO:0016491

sp|P48593|E631_DROME
Calcium-binding protein E63-1
Search

0.42	Calcium-binding protein E63-1

0.38	GO:0006468	protein phosphorylation
0.35	GO:1901002	positive regulation of response to salt stress
0.35	GO:0009738	abscisic acid-activated signaling pathway
0.34	GO:0050832	defense response to fungus
0.34	GO:0018209	peptidyl-serine modification
0.34	GO:0000266	mitochondrial fission
0.34	GO:0016559	peroxisome fission
0.33	GO:0035556	intracellular signal transduction
0.32	GO:0001522	pseudouridine synthesis
0.32	GO:0006351	transcription, DNA-templated

0.70	GO:0005509	calcium ion binding
0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding
0.34	GO:0005516	calmodulin binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.43	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.38	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

GO:0032440

sp|P48596|GCH1_DROME
GTP cyclohydrolase 1
Search

0.39	GTP cyclohydrolase I

0.75	GO:0046654	tetrahydrofolate biosynthetic process
0.47	GO:0043095	regulation of GTP cyclohydrolase I activity
0.47	GO:0035185	preblastoderm mitotic cell cycle
0.46	GO:0046146	tetrahydrobiopterin metabolic process
0.46	GO:0006728	pteridine biosynthetic process
0.46	GO:0034312	diol biosynthetic process
0.46	GO:0048072	compound eye pigmentation
0.46	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.45	GO:0008363	larval chitin-based cuticle development
0.45	GO:0048067	cuticle pigmentation

0.79	GO:0003934	GTP cyclohydrolase I activity
0.47	GO:0060308	GTP cyclohydrolase I regulator activity
0.41	GO:0051019	mitogen-activated protein kinase binding
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.38	GO:0008270	zinc ion binding
0.37	GO:0003924	GTPase activity
0.36	GO:0030742	GTP-dependent protein binding
0.36	GO:0032555	purine ribonucleotide binding

0.49	GO:0005737	cytoplasm
0.40	GO:0031965	nuclear membrane
0.38	GO:0097708	intracellular vesicle
0.38	GO:0005654	nucleoplasm
0.36	GO:0043234	protein complex
0.34	GO:0044306	neuron projection terminus
0.30	GO:0016021	integral component of membrane

0.79	EC:3.5.4.16	GO:0003934
0.79	KEGG:R00424	GO:0003934

sp|P48598|IF4E_DROME
Eukaryotic translation initiation factor 4E
Search

0.59	Eukaryotic translation initiation factor 4E

0.72	GO:0006413	translational initiation
0.51	GO:0048136	male germ-line cyst formation
0.50	GO:0007060	male meiosis chromosome segregation
0.50	GO:0048137	spermatocyte division
0.50	GO:0010032	meiotic chromosome condensation
0.49	GO:0007112	male meiosis cytokinesis
0.47	GO:0045995	regulation of embryonic development
0.47	GO:0048515	spermatid differentiation
0.46	GO:0001558	regulation of cell growth
0.46	GO:0002181	cytoplasmic translation

0.73	GO:0003743	translation initiation factor activity
0.61	GO:0031370	eukaryotic initiation factor 4G binding
0.60	GO:0000340	RNA 7-methylguanosine cap binding
0.36	GO:0003700	DNA binding transcription factor activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0046872	metal ion binding

0.60	GO:0016281	eukaryotic translation initiation factor 4F complex
0.50	GO:0097482	muscle cell postsynaptic specialization
0.47	GO:0000932	P-body
0.36	GO:0005634	nucleus
0.36	GO:0005845	mRNA cap binding complex
0.34	GO:0005829	cytosol

sp|P48601|PRS4_DROME
26S protease regulatory subunit 4
Search

0.70	Regulatory particle triple-A ATPase 2, isoform B

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.52	GO:0006508	proteolysis
0.43	GO:0043632	modification-dependent macromolecule catabolic process
0.40	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.39	GO:0034976	response to endoplasmic reticulum stress
0.39	GO:0010243	response to organonitrogen compound
0.38	GO:0044267	cellular protein metabolic process
0.36	GO:0006383	transcription by RNA polymerase III
0.35	GO:0008063	Toll signaling pathway

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.40	GO:0017025	TBP-class protein binding
0.35	GO:0008568	microtubule-severing ATPase activity
0.34	GO:0008271	secondary active sulfate transmembrane transporter activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.53	GO:1905369	endopeptidase complex
0.48	GO:0005737	cytoplasm
0.46	GO:0043234	protein complex
0.39	GO:0031981	nuclear lumen
0.35	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.30	GO:0016020	membrane

0.50

GO:0008233

sp|P48602|VATA1_DROME
V-type proton ATPase catalytic subunit A isoform 1
Search

0.50	Vacuolar ATP synthase catalytic subunit A

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.62	GO:0046034	ATP metabolic process
0.45	GO:0071453	cellular response to oxygen levels
0.44	GO:0008593	regulation of Notch signaling pathway
0.44	GO:0048388	endosomal lumen acidification
0.44	GO:0007446	imaginal disc growth
0.44	GO:0001666	response to hypoxia
0.44	GO:0035149	lumen formation, open tracheal system
0.41	GO:0016197	endosomal transport
0.39	GO:0033554	cellular response to stress

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0005096	GTPase activator activity
0.32	GO:0046872	metal ion binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.44	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.39	GO:0005765	lysosomal membrane
0.37	GO:0016324	apical plasma membrane
0.36	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.34	GO:0005902	microvillus
0.34	GO:0043209	myelin sheath
0.33	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion

sp|P48603|CAPZB_DROME
F-actin-capping protein subunit beta
Search

0.72	F-actin-capping protein subunit beta

0.84	GO:0051016	barbed-end actin filament capping
0.73	GO:0030036	actin cytoskeleton organization
0.52	GO:0051490	negative regulation of filopodium assembly
0.51	GO:0010591	regulation of lamellipodium assembly
0.48	GO:0031115	negative regulation of microtubule polymerization
0.48	GO:0048468	cell development
0.47	GO:0090036	regulation of protein kinase C signaling
0.47	GO:0030032	lamellipodium assembly
0.47	GO:0048731	system development
0.46	GO:0045887	positive regulation of synaptic growth at neuromuscular junction

0.73	GO:0003779	actin binding
0.46	GO:0048487	beta-tubulin binding
0.46	GO:0032403	protein complex binding
0.42	GO:0046982	protein heterodimerization activity
0.35	GO:0045296	cadherin binding

0.84	GO:0008290	F-actin capping protein complex
0.49	GO:0005737	cytoplasm
0.48	GO:0030054	cell junction
0.46	GO:0005903	brush border
0.46	GO:0097223	sperm part
0.46	GO:0030027	lamellipodium
0.45	GO:0099512	supramolecular fiber
0.43	GO:0031982	vesicle
0.41	GO:0012505	endomembrane system
0.38	GO:0071944	cell periphery

sp|P48604|GRPE_DROME
GrpE protein homolog, mitochondrial
Search

0.75	GrpE protein like protein 1, mitochondrial

0.69	GO:0006457	protein folding
0.69	GO:0050790	regulation of catalytic activity
0.43	GO:0030150	protein import into mitochondrial matrix
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.33	GO:0030329	prenylcysteine metabolic process
0.33	GO:0000098	sulfur amino acid catabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0042219	cellular modified amino acid catabolic process

0.79	GO:0000774	adenyl-nucleotide exchange factor activity
0.77	GO:0051087	chaperone binding
0.75	GO:0042803	protein homodimerization activity
0.44	GO:0051082	unfolded protein binding
0.35	GO:0003735	structural constituent of ribosome
0.33	GO:0001735	prenylcysteine oxidase activity
0.33	GO:0016853	isomerase activity

0.73	GO:0005759	mitochondrial matrix
0.45	GO:0001405	presequence translocase-associated import motor
0.34	GO:0005840	ribosome
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

EC:1.8.3.5

GO:0001735

sp|P48605|TCPG_DROME
T-complex protein 1 subunit gamma
Search

0.69	T-complex protein 1 subunit gamma

0.69	GO:0006457	protein folding
0.39	GO:0046671	negative regulation of retinal cell programmed cell death
0.38	GO:0048048	embryonic eye morphogenesis
0.35	GO:0007430	terminal branching, open tracheal system
0.35	GO:0035149	lumen formation, open tracheal system
0.34	GO:0042981	regulation of apoptotic process

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0044183	protein binding involved in protein folding
0.33	GO:0042623	ATPase activity, coupled

0.48	GO:0005737	cytoplasm
0.41	GO:0101031	chaperone complex
0.30	GO:0016020	membrane

sp|P48607|SPZ_DROME
Protein spaetzle
Search

SPZ

0.81

Spatzle

0.85	GO:0002816	regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
0.84	GO:0002810	regulation of antifungal peptide biosynthetic process
0.83	GO:0002804	positive regulation of antifungal peptide production
0.83	GO:0045752	positive regulation of Toll signaling pathway
0.82	GO:0006963	positive regulation of antibacterial peptide biosynthetic process
0.81	GO:0007526	larval somatic muscle development
0.81	GO:0019732	antifungal humoral response
0.80	GO:0007310	oocyte dorsal/ventral axis specification
0.78	GO:0008063	Toll signaling pathway
0.78	GO:0008045	motor neuron axon guidance

0.84	GO:0005121	Toll binding
0.71	GO:0008083	growth factor activity
0.68	GO:0042803	protein homodimerization activity
0.62	GO:0016015	morphogen activity
0.55	GO:0005125	cytokine activity

0.61	GO:0005576	extracellular region
0.55	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P48608|DIA_DROME
Protein diaphanous
Search

0.87	Diaphanous

0.74	GO:0007015	actin filament organization
0.66	GO:0007049	cell cycle
0.38	GO:0106036	assembly of apicomedial cortex actomyosin
0.38	GO:0030589	pseudocleavage involved in syncytial blastoderm formation
0.38	GO:0007279	pole cell formation
0.37	GO:0035011	melanotic encapsulation of foreign target
0.37	GO:0003383	apical constriction
0.37	GO:0016476	regulation of embryonic cell shape
0.37	GO:0097320	plasma membrane tubulation
0.37	GO:0051489	regulation of filopodium assembly

0.75	GO:0017048	Rho GTPase binding
0.74	GO:0003779	actin binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.30	GO:0003824	catalytic activity

0.38	GO:0035230	cytoneme
0.37	GO:0032154	cleavage furrow
0.36	GO:0005884	actin filament
0.36	GO:0016324	apical plasma membrane
0.36	GO:0005912	adherens junction
0.36	GO:0012506	vesicle membrane
0.36	GO:0005938	cell cortex
0.34	GO:0043234	protein complex

sp|P48609|CDK5_DROME
Cyclin-dependent kinase 5 homolog
Search

CDK5

0.58	Cell division protein kinase

0.63	GO:0006468	protein phosphorylation
0.50	GO:0048666	neuron development
0.49	GO:0051726	regulation of cell cycle
0.48	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.48	GO:0000904	cell morphogenesis involved in differentiation
0.48	GO:0050807	regulation of synapse organization
0.48	GO:0030534	adult behavior
0.47	GO:0006915	apoptotic process
0.47	GO:0120036	plasma membrane bounded cell projection organization
0.47	GO:0035011	melanotic encapsulation of foreign target

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0097472	cyclin-dependent protein kinase activity
0.43	GO:0035173	histone kinase activity
0.42	GO:0030549	acetylcholine receptor activator activity
0.42	GO:0043125	ErbB-3 class receptor binding
0.41	GO:0005176	ErbB-2 class receptor binding

0.47	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.42	GO:0045202	synapse
0.40	GO:0030175	filopodium
0.40	GO:0005829	cytosol
0.40	GO:0030027	lamellipodium
0.40	GO:0030424	axon
0.39	GO:0030054	cell junction
0.38	GO:0005634	nucleus
0.36	GO:0030426	growth cone
0.36	GO:0043025	neuronal cell body

0.68

GO:0004674

sp|P48610|KARG_DROME
Arginine kinase
Search

0.72	ATP:guanido phosphotransferase

0.57	GO:0016310	phosphorylation
0.39	GO:0019509	L-methionine salvage from methylthioadenosine
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0055114	oxidation-reduction process
0.32	GO:0006508	proteolysis

0.60	GO:0016301	kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity
0.38	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.37	GO:0016868	intramolecular transferase activity, phosphotransferases
0.36	GO:0005506	iron ion binding
0.36	GO:0000287	magnesium ion binding
0.32	GO:0004222	metalloendopeptidase activity

0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40	EC:1.13.11.54	GO:0010309
0.40	KEGG:R07364	GO:0010309

sp|P48611|PTPS_DROME
6-pyruvoyl tetrahydrobiopterin synthase
Search

0.60	6-pyruvoyl tetrahydrobiopterin synthase

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.64	GO:0009108	coenzyme biosynthetic process
0.51	GO:0019889	pteridine metabolic process
0.43	GO:0046148	pigment biosynthetic process
0.34	GO:0008616	queuosine biosynthetic process
0.34	GO:0043604	amide biosynthetic process
0.34	GO:0046655	folic acid metabolic process
0.33	GO:0006979	response to oxidative stress

0.85	GO:0003874	6-pyruvoyltetrahydropterin synthase activity
0.42	GO:0046872	metal ion binding
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0004831	tyrosine-tRNA ligase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0022625	cytosolic large ribosomal subunit
0.33	GO:0005739	mitochondrion

0.85	EC:4.2.3.12	GO:0003874
0.85	KEGG:R04286	GO:0003874

sp|P48612|PELO_DROME
Protein pelota
Search

0.10	Putative meiotic cell division protein pelota/dom34 (Fragment)

0.85	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay
0.84	GO:0070481	nuclear-transcribed mRNA catabolic process, non-stop decay
0.83	GO:0071025	RNA surveillance
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.51	GO:0019827	stem cell population maintenance
0.49	GO:0051078	meiotic nuclear envelope disassembly
0.47	GO:0048132	female germ-line stem cell asymmetric division
0.47	GO:0048137	spermatocyte division
0.46	GO:0000212	meiotic spindle organization
0.46	GO:0060231	mesenchymal to epithelial transition

0.64	GO:0004519	endonuclease activity
0.52	GO:0046872	metal ion binding
0.42	GO:0043022	ribosome binding
0.34	GO:0098639	collagen binding involved in cell-matrix adhesion
0.34	GO:0019903	protein phosphatase binding

0.59	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.48	GO:1990533	Dom34-Hbs1 complex
0.35	GO:0034665	integrin alpha1-beta1 complex
0.34	GO:0045178	basal part of cell
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0005925	focal adhesion

sp|P48613|TIPE_DROME
Protein tipE
Search

0.68	GO:0045433	male courtship behavior, veined wing generated song production
0.65	GO:0002028	regulation of sodium ion transport
0.62	GO:0034605	cellular response to heat
0.53	GO:0065009	regulation of molecular function
0.39	GO:0035725	sodium ion transmembrane transport

0.66	GO:0017080	sodium channel regulator activity
0.41	GO:0005248	voltage-gated sodium channel activity

0.53

GO:0005887

integral component of plasma membrane

sp|P48809|RB27C_DROME
Heterogeneous nuclear ribonucleoprotein 27C
Search

0.76	RNA-binding protein musashi

0.52	GO:0045451	pole plasm oskar mRNA localization
0.51	GO:0007298	border follicle cell migration
0.50	GO:0048024	regulation of mRNA splicing, via spliceosome
0.49	GO:0007411	axon guidance
0.48	GO:0045727	positive regulation of translation
0.37	GO:0007319	negative regulation of oskar mRNA translation

0.59	GO:0003723	RNA binding
0.46	GO:0003697	single-stranded DNA binding
0.34	GO:0005515	protein binding

0.54	GO:0019013	viral nucleocapsid
0.51	GO:0043186	P granule
0.45	GO:0005654	nucleoplasm
0.41	GO:0043234	protein complex
0.35	GO:0005730	nucleolus

sp|P48810|RB87F_DROME
Heterogeneous nuclear ribonucleoprotein 87F
Search

0.70	Putative rna-binding protein musashi/mrna cleavage and polyadenylation factor i complex

0.53	GO:0001745	compound eye morphogenesis
0.53	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.49	GO:0003006	developmental process involved in reproduction
0.46	GO:0061458	reproductive system development
0.46	GO:0042594	response to starvation
0.45	GO:0036099	female germ-line stem cell population maintenance
0.45	GO:0009408	response to heat
0.45	GO:0033119	negative regulation of RNA splicing
0.43	GO:0007292	female gamete generation
0.42	GO:0022412	cellular process involved in reproduction in multicellular organism

0.59	GO:0003723	RNA binding
0.45	GO:0043565	sequence-specific DNA binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005703	polytene chromosome puff
0.53	GO:0019013	viral nucleocapsid
0.52	GO:0030529	intracellular ribonucleoprotein complex
0.51	GO:0035062	omega speckle
0.47	GO:0000792	heterochromatin
0.33	GO:0030286	dynein complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P48987|ATO_DROME
Protein atonal
Search

0.11

Atonal

0.64	GO:0048801	antennal joint morphogenesis
0.62	GO:0007438	oenocyte development
0.62	GO:0001748	optic lobe placode development
0.62	GO:0007460	R8 cell fate commitment
0.62	GO:0001746	Bolwig's organ morphogenesis
0.61	GO:0045433	male courtship behavior, veined wing generated song production
0.61	GO:0016360	sensory organ precursor cell fate determination
0.58	GO:0007173	epidermal growth factor receptor signaling pathway
0.58	GO:0008038	neuron recognition
0.57	GO:0007224	smoothened signaling pathway

0.68	GO:0046983	protein dimerization activity
0.52	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0003677	DNA binding
0.30	GO:0003824	catalytic activity

0.46

GO:0005634

nucleus

sp|P48994|TRPL_DROME
Transient-receptor-potential-like protein
Search

TRPL

0.59	Short transient receptor potential channel

0.77	GO:0070588	calcium ion transmembrane transport
0.53	GO:0071454	cellular response to anoxia
0.53	GO:0007603	phototransduction, visible light
0.50	GO:0007605	sensory perception of sound
0.50	GO:0007589	body fluid secretion
0.49	GO:0019722	calcium-mediated signaling
0.42	GO:0050908	detection of light stimulus involved in visual perception
0.41	GO:0006828	manganese ion transport
0.41	GO:0051480	regulation of cytosolic calcium ion concentration
0.40	GO:0008355	olfactory learning

0.80	GO:0005262	calcium channel activity
0.52	GO:0010461	light-activated ion channel activity
0.47	GO:0005516	calmodulin binding
0.47	GO:0046982	protein heterodimerization activity
0.47	GO:0042802	identical protein binding
0.32	GO:0016740	transferase activity

0.55	GO:0035997	rhabdomere microvillus membrane
0.54	GO:0016027	inaD signaling complex
0.48	GO:0034703	cation channel complex
0.48	GO:0030425	dendrite
0.38	GO:0005887	integral component of plasma membrane
0.35	GO:0005622	intracellular

0.32

GO:0016740

sp|P49021|TIM_DROME
Protein timeless
Search

TIM

0.68

Timeless

0.77	GO:0048511	rhythmic process
0.75	GO:0052129	negative energy taxis
0.75	GO:0007562	eclosion
0.72	GO:0042331	phototaxis
0.71	GO:0007620	copulation
0.70	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.70	GO:0030431	sleep
0.70	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.70	GO:0001659	temperature homeostasis
0.70	GO:0009649	entrainment of circadian clock

0.60	GO:0046982	protein heterodimerization activity
0.59	GO:0008134	transcription factor binding
0.42	GO:0016853	isomerase activity

0.76	GO:0048471	perinuclear region of cytoplasm
0.59	GO:0005634	nucleus
0.57	GO:0005829	cytosol
0.56	GO:0043233	organelle lumen
0.50	GO:0043234	protein complex
0.49	GO:0044446	intracellular organelle part

0.42

EC:5

GO:0016853

sp|P49028|MGN_DROME
Protein mago nashi
Search

0.85	Exon-exon junction complex magoh component

0.45	GO:0000335	negative regulation of transposition, DNA-mediated
0.45	GO:0008103	oocyte microtubule cytoskeleton polarization
0.45	GO:0007317	regulation of pole plasm oskar mRNA localization
0.43	GO:0007173	epidermal growth factor receptor signaling pathway
0.42	GO:0008380	RNA splicing
0.38	GO:0008104	protein localization
0.36	GO:0046594	maintenance of pole plasm mRNA location
0.35	GO:0045451	pole plasm oskar mRNA localization
0.35	GO:0046579	positive regulation of Ras protein signal transduction
0.35	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.33	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.43	GO:0045495	pole plasm
0.38	GO:0043234	protein complex
0.38	GO:0044446	intracellular organelle part
0.36	GO:1902494	catalytic complex
0.35	GO:0030529	intracellular ribonucleoprotein complex

sp|P49071|MAPK2_DROME
MAP kinase-activated protein kinase 2
Search

0.49	Mitogen-activated protein kinase-activated protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.48	GO:0018209	peptidyl-serine modification
0.47	GO:0044351	macropinocytosis
0.46	GO:0080134	regulation of response to stress
0.46	GO:0045793	positive regulation of cell size
0.45	GO:0034097	response to cytokine
0.45	GO:0032496	response to lipopolysaccharide
0.44	GO:0002757	immune response-activating signal transduction
0.44	GO:0009651	response to salt stress
0.44	GO:0043408	regulation of MAPK cascade

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0051019	mitogen-activated protein kinase binding
0.46	GO:0010857	calcium-dependent protein kinase activity
0.44	GO:0005516	calmodulin binding
0.41	GO:0004871	signal transducer activity
0.35	GO:0004872	receptor activity
0.35	GO:0043565	sequence-specific DNA binding

0.42	GO:0005654	nucleoplasm
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.67

GO:0004674

sp|P49258|CALL_DROME
Calmodulin-related protein 97A
Search

0.45	Calmoduline

0.37	GO:0061122	positive regulation of positive chemotaxis to cAMP
0.37	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.37	GO:1903665	negative regulation of asexual reproduction
0.36	GO:0072666	establishment of protein localization to vacuole
0.36	GO:0032781	positive regulation of ATPase activity
0.36	GO:0000281	mitotic cytokinesis
0.35	GO:0030048	actin filament-based movement
0.35	GO:0045861	negative regulation of proteolysis
0.35	GO:0043549	regulation of kinase activity
0.34	GO:0008218	bioluminescence

0.70	GO:0005509	calcium ion binding
0.47	GO:0070855	myosin VI head/neck binding
0.37	GO:0017024	myosin I binding
0.37	GO:0031013	troponin I binding
0.36	GO:0050839	cell adhesion molecule binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.47	GO:0031476	myosin VI complex
0.46	GO:0070865	investment cone
0.39	GO:0005634	nucleus
0.37	GO:0000331	contractile vacuole
0.35	GO:0031012	extracellular matrix
0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0032440

sp|P49283|MVL_DROME
Protein Malvolio
Search

MVL

0.89	Divalent metal transporter

0.66	GO:0030001	metal ion transport
0.38	GO:0060586	multicellular organismal iron ion homeostasis
0.37	GO:0051050	positive regulation of transport
0.36	GO:0045342	MHC class II biosynthetic process
0.36	GO:0032632	interleukin-3 production
0.36	GO:0006879	cellular iron ion homeostasis
0.36	GO:0006876	cellular cadmium ion homeostasis
0.36	GO:0034759	regulation of iron ion transmembrane transport
0.36	GO:0002309	T cell proliferation involved in immune response
0.36	GO:0002606	positive regulation of dendritic cell antigen processing and presentation

0.69	GO:0046873	metal ion transmembrane transporter activity
0.35	GO:0015291	secondary active transmembrane transporter activity
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.36	GO:0005768	endosome
0.36	GO:0070821	tertiary granule membrane
0.36	GO:0030670	phagocytic vesicle membrane
0.35	GO:0005764	lysosome
0.34	GO:0005887	integral component of plasma membrane

sp|P49415|SDC_DROME
Syndecan
Search

0.60

Syndecan

0.79	GO:0007411	axon guidance
0.40	GO:0007427	epithelial cell migration, open tracheal system
0.40	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.40	GO:0097009	energy homeostasis
0.40	GO:0050908	detection of light stimulus involved in visual perception
0.40	GO:2000637	positive regulation of gene silencing by miRNA
0.40	GO:0044246	regulation of multicellular organismal metabolic process
0.39	GO:0021782	glial cell development
0.38	GO:0007517	muscle organ development
0.38	GO:0006487	protein N-linked glycosylation

0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0016849	phosphorus-oxygen lyase activity
0.32	GO:0046872	metal ion binding

0.40	GO:0098595	perivitelline space
0.39	GO:0034998	oligosaccharyltransferase I complex
0.39	GO:0009986	cell surface
0.39	GO:0031594	neuromuscular junction
0.39	GO:0005925	focal adhesion
0.35	GO:0005861	troponin complex
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:4.6

GO:0016849

sp|P49455|TPM4_DROME
Tropomyosin-1, isoforms 33/34
Search

0.48	Tropomyosin

0.72	GO:0045451	pole plasm oskar mRNA localization
0.71	GO:0055093	response to hyperoxia
0.70	GO:0043149	stress fiber assembly
0.70	GO:0010591	regulation of lamellipodium assembly
0.68	GO:0048813	dendrite morphogenesis
0.66	GO:0006936	muscle contraction
0.52	GO:0060298	positive regulation of sarcomere organization
0.48	GO:0007507	heart development

0.69	GO:0008307	structural constituent of muscle
0.67	GO:0019894	kinesin binding
0.63	GO:0051015	actin filament binding
0.52	GO:0004813	alanine-tRNA ligase activity
0.38	GO:0019901	protein kinase binding

0.74	GO:0070865	investment cone
0.72	GO:0005862	muscle thin filament tropomyosin
0.69	GO:0031941	filamentous actin
0.68	GO:0016529	sarcoplasmic reticulum
0.68	GO:0043186	P granule
0.67	GO:0097517	contractile actin filament bundle
0.67	GO:0042641	actomyosin
0.64	GO:0030864	cortical actin cytoskeleton
0.57	GO:0005829	cytosol

0.52

EC:6.1.1.7

GO:0004813

sp|P49630|RL36_DROME
60S ribosomal protein L36
Search

0.70	60S ribosomal protein L36

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process

0.63	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.43	GO:0005730	nucleolus
0.42	GO:0000228	nuclear chromosome
0.38	GO:0044445	cytosolic part
0.38	GO:0005844	polysome
0.30	GO:0031224	intrinsic component of membrane

sp|P49657|MNB_DROME
Serine/threonine-protein kinase minibrain
Search

0.81	Serine/threonine-protein kinase minibrain

0.77	GO:0046777	protein autophosphorylation
0.49	GO:0018108	peptidyl-tyrosine phosphorylation
0.38	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.38	GO:0035332	positive regulation of hippo signaling
0.38	GO:2000253	positive regulation of feeding behavior
0.38	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.38	GO:0008355	olfactory learning
0.38	GO:0007632	visual behavior
0.37	GO:0007623	circadian rhythm
0.37	GO:0045666	positive regulation of neuron differentiation

0.77	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004674	protein serine/threonine kinase activity
0.49	GO:0004713	protein tyrosine kinase activity
0.35	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity

0.37	GO:0043195	terminal bouton
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77

EC:2.7.12.1

GO:0004712

sp|P49735|MCM2_DROME
DNA replication licensing factor Mcm2
Search

0.44	DNA replication licensing factor Mcm2

0.75	GO:0006270	DNA replication initiation
0.70	GO:0032392	DNA geometric change
0.47	GO:0071353	cellular response to interleukin-4
0.47	GO:0090102	cochlea development
0.47	GO:0006323	DNA packaging
0.44	GO:0006333	chromatin assembly or disassembly
0.44	GO:0034728	nucleosome organization
0.44	GO:0006915	apoptotic process
0.44	GO:0065004	protein-DNA complex assembly
0.40	GO:0048538	thymus development

0.71	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042393	histone binding
0.42	GO:0019899	enzyme binding
0.39	GO:0003682	chromatin binding
0.34	GO:0003883	CTP synthase activity
0.34	GO:0046872	metal ion binding

0.80	GO:0042555	MCM complex
0.61	GO:0005634	nucleus
0.45	GO:0000808	origin recognition complex
0.43	GO:0000785	chromatin
0.42	GO:0015630	microtubule cytoskeleton
0.42	GO:0031974	membrane-enclosed lumen
0.36	GO:0005737	cytoplasm
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0005667	transcription factor complex
0.34	GO:0000781	chromosome, telomeric region

0.34

EC:6.3.4.2

GO:0003883

sp|P49762|DOA_DROME
Serine/threonine-protein kinase Doa
Search

0.10	Serine/threonine-protein kinase Doa

0.63	GO:0006468	protein phosphorylation
0.49	GO:0034125	negative regulation of MyD88-dependent toll-like receptor signaling pathway
0.48	GO:2000255	negative regulation of male germ cell proliferation
0.47	GO:0030717	karyosome formation
0.47	GO:0042051	compound eye photoreceptor development
0.46	GO:0007350	blastoderm segmentation
0.45	GO:0007548	sex differentiation
0.42	GO:0009306	protein secretion
0.32	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.31	GO:0007601	visual perception

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.42	GO:0005783	endoplasmic reticulum
0.39	GO:0005634	nucleus
0.31	GO:0005829	cytosol

sp|P49846|TAF5_DROME
Transcription initiation factor TFIID subunit 5
Search

0.50	Transcription initiation factor TFIID subunit

0.62	GO:0006413	translational initiation
0.60	GO:0006367	transcription initiation from RNA polymerase II promoter
0.58	GO:0007221	positive regulation of transcription of Notch receptor target
0.54	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.50	GO:0016573	histone acetylation
0.35	GO:0042795	snRNA transcription by RNA polymerase II
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0006368	transcription elongation from RNA polymerase II promoter
0.33	GO:0016032	viral process

0.63	GO:0003743	translation initiation factor activity
0.58	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.50	GO:0004402	histone acetyltransferase activity
0.48	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0042802	identical protein binding
0.45	GO:0046983	protein dimerization activity
0.34	GO:0032947	protein complex scaffold activity
0.34	GO:0043130	ubiquitin binding
0.34	GO:0003682	chromatin binding

0.60	GO:0005669	transcription factor TFIID complex
0.52	GO:0033276	transcription factor TFTC complex
0.47	GO:0000790	nuclear chromatin
0.47	GO:0015629	actin cytoskeleton
0.36	GO:0005730	nucleolus
0.34	GO:0019013	viral nucleocapsid
0.34	GO:0046695	SLIK (SAGA-like) complex
0.34	GO:0000124	SAGA complex
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.50

GO:0004402

sp|P49847|TAF6_DROME
Transcription initiation factor TFIID subunit 6
Search

TAF6

0.59	Transcription initiation factor TFIID subunit

0.80	GO:0051090	regulation of DNA binding transcription factor activity
0.69	GO:0006352	DNA-templated transcription, initiation
0.53	GO:0006413	translational initiation
0.48	GO:0007221	positive regulation of transcription of Notch receptor target
0.48	GO:0006366	transcription by RNA polymerase II
0.44	GO:0065004	protein-DNA complex assembly
0.41	GO:0045786	negative regulation of cell cycle
0.36	GO:0008285	negative regulation of cell proliferation
0.34	GO:0009301	snRNA transcription
0.34	GO:1901796	regulation of signal transduction by p53 class mediator

0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003743	translation initiation factor activity
0.48	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.45	GO:0017162	aryl hydrocarbon receptor binding
0.37	GO:0003677	DNA binding

0.82	GO:0046695	SLIK (SAGA-like) complex
0.80	GO:0000124	SAGA complex
0.80	GO:0005669	transcription factor TFIID complex
0.44	GO:0033276	transcription factor TFTC complex
0.43	GO:0071339	MLL1 complex
0.40	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P49858|CNI_DROME
Protein cornichon
Search

0.80	Putative er vesicle integral membrane protein involved in establishing cell polarity

0.69	GO:0016192	vesicle-mediated transport
0.48	GO:0007310	oocyte dorsal/ventral axis specification
0.48	GO:0046843	dorsal appendage formation
0.46	GO:0007350	blastoderm segmentation
0.45	GO:0009952	anterior/posterior pattern specification
0.42	GO:0046907	intracellular transport
0.36	GO:0008314	gurken signaling pathway
0.35	GO:0000578	embryonic axis specification
0.34	GO:0015031	protein transport
0.34	GO:0006468	protein phosphorylation

0.34	GO:0005515	protein binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0044877	macromolecular complex binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0000139	Golgi membrane
0.34	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0012507	ER to Golgi transport vesicle membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0016758

sp|P49866|HNF4_DROME
Transcription factor HNF-4 homolog
Search

HNF4

0.92	Transcription factor HNF-4

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0030522	intracellular receptor signaling pathway
0.44	GO:2000189	positive regulation of cholesterol homeostasis
0.43	GO:0055091	phospholipid homeostasis
0.43	GO:0070328	triglyceride homeostasis
0.43	GO:0010470	regulation of gastrulation

0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0001102	RNA polymerase II activating transcription factor binding
0.42	GO:0005504	fatty acid binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0003690	double-stranded DNA binding
0.39	GO:0005102	receptor binding

0.61	GO:0005634	nucleus
0.39	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P49869|HR38_DROME
Probable nuclear hormone receptor HR38
Search

0.66	Nuclear receptor subfamily 4 group A member 2

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.74	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.53	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.51	GO:0042335	cuticle development
0.46	GO:0051866	general adaptation syndrome
0.45	GO:0071376	cellular response to corticotropin-releasing hormone stimulus

0.80	GO:0003707	steroid hormone receptor activity
0.76	GO:0004879	nuclear receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0001047	core promoter binding
0.50	GO:0046982	protein heterodimerization activity
0.49	GO:0005102	receptor binding
0.49	GO:0003690	double-stranded DNA binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm

sp|P49905|TAF12_DROME
Transcription initiation factor TFIID subunit 12
Search

TAF12

0.62	Transcription initiation factor TFIID subunit

0.69	GO:0006352	DNA-templated transcription, initiation
0.57	GO:0006413	translational initiation
0.56	GO:0043966	histone H3 acetylation
0.52	GO:0006366	transcription by RNA polymerase II
0.49	GO:0065004	protein-DNA complex assembly
0.46	GO:0051091	positive regulation of DNA binding transcription factor activity
0.36	GO:0007221	positive regulation of transcription of Notch receptor target
0.34	GO:1901796	regulation of signal transduction by p53 class mediator
0.33	GO:0006354	DNA-templated transcription, elongation
0.33	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA

0.74	GO:0046982	protein heterodimerization activity
0.58	GO:0003743	translation initiation factor activity
0.54	GO:0004402	histone acetyltransferase activity
0.50	GO:0008134	transcription factor binding
0.49	GO:0000989	transcription factor activity, transcription factor binding
0.48	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.44	GO:0042803	protein homodimerization activity
0.40	GO:0003677	DNA binding
0.31	GO:0016787	hydrolase activity

0.82	GO:0046695	SLIK (SAGA-like) complex
0.80	GO:0000124	SAGA complex
0.80	GO:0005669	transcription factor TFIID complex
0.48	GO:0030914	STAGA complex
0.47	GO:0033276	transcription factor TFTC complex
0.38	GO:0000125	PCAF complex
0.30	GO:0016020	membrane

0.54

GO:0004402

sp|P49906|TAF11_DROME
Transcription initiation factor TFIID subunit 11
Search

TAF11

0.66	Transcription initiation factor TFIID subunit

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.58	GO:0006413	translational initiation
0.52	GO:1901092	positive regulation of protein tetramerization
0.51	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.51	GO:1900370	positive regulation of RNA interference
0.47	GO:0043923	positive regulation by host of viral transcription
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:1901796	regulation of signal transduction by p53 class mediator

0.74	GO:0046982	protein heterodimerization activity
0.58	GO:0003743	translation initiation factor activity
0.50	GO:0008134	transcription factor binding
0.50	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.48	GO:0003713	transcription coactivator activity
0.46	GO:0047485	protein N-terminus binding
0.45	GO:0051427	hormone receptor binding
0.35	GO:0003677	DNA binding
0.34	GO:0070006	metalloaminopeptidase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.51	GO:0000428	DNA-directed RNA polymerase complex
0.51	GO:0005667	transcription factor complex
0.50	GO:0070578	RISC-loading complex
0.48	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005794	Golgi apparatus
0.37	GO:0030529	intracellular ribonucleoprotein complex

sp|P49963|SRP19_DROME
Signal recognition particle 19 kDa protein
Search

SRP19

0.39	Signal recognition particle

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.40	GO:0065002	intracellular protein transmembrane transport
0.39	GO:0043623	cellular protein complex assembly
0.34	GO:0006730	one-carbon metabolic process

0.78	GO:0008312	7S RNA binding
0.34	GO:0004089	carbonate dehydratase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016787	hydrolase activity

0.77	GO:0048500	signal recognition particle
0.30	GO:0016021	integral component of membrane

0.34

EC:4.2.1.1

GO:0004089

sp|P50245|SAHH2_DROME
Putative adenosylhomocysteinase 2
Search

0.56	Adenosylhomocysteinase

0.72	GO:0006730	one-carbon metabolic process
0.38	GO:0033353	S-adenosylmethionine cycle
0.33	GO:0006030	chitin metabolic process
0.33	GO:0006508	proteolysis

0.80	GO:0004013	adenosylhomocysteinase activity
0.33	GO:0008061	chitin binding
0.33	GO:0008236	serine-type peptidase activity

0.37	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.80

EC:3.3.1.1

GO:0004013

sp|P50445|RUX_DROME
Cell cycle negative regulator roughex
Search

sp|P50534|MSL2_DROME
E3 ubiquitin-protein ligase msl-2
Search

MSL2

0.97	Male-specific lethal 2

0.73	GO:0016567	protein ubiquitination
0.60	GO:0007549	dosage compensation
0.42	GO:0043984	histone H4-K16 acetylation
0.39	GO:0065004	protein-DNA complex assembly

0.76	GO:0061630	ubiquitin protein ligase activity
0.54	GO:0003682	chromatin binding
0.52	GO:0008134	transcription factor binding
0.43	GO:0003677	DNA binding
0.39	GO:0016874	ligase activity
0.35	GO:0046872	metal ion binding

0.85	GO:0072487	MSL complex
0.62	GO:0046536	dosage compensation complex
0.60	GO:0000805	X chromosome
0.52	GO:0000228	nuclear chromosome
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016874

sp|P50535|MSL1_DROME
Protein male-specific lethal-1
Search

MSL-1

0.78	Male-specific lethal 1

0.86	GO:0043984	histone H4-K16 acetylation
0.71	GO:0007549	dosage compensation
0.70	GO:0031936	negative regulation of chromatin silencing
0.40	GO:0065004	protein-DNA complex assembly
0.32	GO:0007155	cell adhesion
0.32	GO:0016567	protein ubiquitination

0.65	GO:0031625	ubiquitin protein ligase binding
0.63	GO:0003682	chromatin binding
0.62	GO:0044212	transcription regulatory region DNA binding
0.57	GO:0046983	protein dimerization activity
0.32	GO:0004842	ubiquitin-protein transferase activity

0.85	GO:0072487	MSL complex
0.75	GO:0046536	dosage compensation complex
0.60	GO:0000228	nuclear chromosome
0.42	GO:0000805	X chromosome
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.32

GO:0004842

sp|P50536|MSL3_DROME
Protein male-specific lethal-3
Search

MSL3

0.83	Male specific lethal 3

0.74	GO:0016569	covalent chromatin modification
0.73	GO:0035206	regulation of hemocyte proliferation
0.72	GO:0007549	dosage compensation
0.71	GO:0031936	negative regulation of chromatin silencing
0.58	GO:0006351	transcription, DNA-templated
0.40	GO:0006476	protein deacetylation
0.40	GO:0018393	internal peptidyl-lysine acetylation
0.39	GO:0006338	chromatin remodeling
0.34	GO:0006342	chromatin silencing
0.33	GO:0016024	CDP-diacylglycerol biosynthetic process

0.69	GO:0035064	methylated histone binding
0.64	GO:0003682	chromatin binding
0.51	GO:0003723	RNA binding
0.33	GO:0016740	transferase activity
0.33	GO:0003779	actin binding
0.32	GO:0017111	nucleoside-triphosphatase activity
0.32	GO:0003677	DNA binding

0.73	GO:0000805	X chromosome
0.71	GO:0010369	chromocenter
0.70	GO:0072487	MSL complex
0.69	GO:0005700	polytene chromosome
0.61	GO:0000228	nuclear chromosome
0.41	GO:0046536	dosage compensation complex
0.40	GO:0035267	NuA4 histone acetyltransferase complex
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.33

GO:0016740

sp|P50882|RL9_DROME
60S ribosomal protein L9
Search

0.72	Sogatella furcifera 60S ribosomal protein L9 mRNA

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0031047	gene silencing by RNA
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:0009100	glycoprotein metabolic process
0.33	GO:0043039	tRNA aminoacylation
0.32	GO:1901137	carbohydrate derivative biosynthetic process
0.32	GO:0036211	protein modification process

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0004813	alanine-tRNA ligase activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.35	GO:0044445	cytosolic part
0.34	GO:0044446	intracellular organelle part
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:6.1.1.7

GO:0004813

sp|P50887|RL22_DROME
60S ribosomal protein L22
Search

0.43	Ribosomal protein L22

0.57	GO:0043043	peptide biosynthetic process
0.53	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.50	GO:0009059	macromolecule biosynthetic process
0.37	GO:0006334	nucleosome assembly
0.34	GO:0009234	menaquinone biosynthetic process
0.34	GO:0045905	positive regulation of translational termination
0.34	GO:0045901	positive regulation of translational elongation
0.34	GO:0006879	cellular iron ion homeostasis
0.33	GO:0006099	tricarboxylic acid cycle

0.60	GO:0003735	structural constituent of ribosome
0.36	GO:0003723	RNA binding
0.35	GO:0003677	DNA binding
0.35	GO:0102955	S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity
0.34	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity
0.34	GO:0008199	ferric iron binding
0.33	GO:0009002	serine-type D-Ala-D-Ala carboxypeptidase activity
0.33	GO:0030976	thiamine pyrophosphate binding
0.33	GO:0043022	ribosome binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.58	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.36	GO:0000786	nucleosome
0.32	GO:0005634	nucleus
0.32	GO:0005769	early endosome
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.2.4.2

GO:0004591

sp|P51023|PNT2_DROME
ETS-like protein pointed, isoform P2/D
Search

0.87	Transforming protein p54/c-ets-1

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0007429	secondary branching, open tracheal system
0.52	GO:0007428	primary branching, open tracheal system
0.52	GO:0009997	negative regulation of cardioblast cell fate specification
0.52	GO:0035225	determination of genital disc primordium
0.52	GO:0061320	pericardial nephrocyte differentiation
0.52	GO:0007464	R3/R4 cell fate commitment
0.52	GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0070491	repressing transcription factor binding
0.47	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.38	GO:0042802	identical protein binding
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0035035	histone acetyltransferase binding
0.33	GO:0005249	voltage-gated potassium channel activity

0.61	GO:0005634	nucleus
0.38	GO:0005667	transcription factor complex
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.33	GO:0008076	voltage-gated potassium channel complex
0.32	GO:0005737	cytoplasm

sp|P51123|TAF1_DROME
Transcription initiation factor TFIID subunit 1
Search

0.64	Transcription initiation factor TFIID subunit

0.63	GO:0006352	DNA-templated transcription, initiation
0.56	GO:0006413	translational initiation
0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.51	GO:0006468	protein phosphorylation
0.39	GO:0016573	histone acetylation
0.39	GO:0065004	protein-DNA complex assembly
0.38	GO:0006366	transcription by RNA polymerase II
0.38	GO:0051254	positive regulation of RNA metabolic process

0.57	GO:0003743	translation initiation factor activity
0.56	GO:0004674	protein serine/threonine kinase activity
0.51	GO:0003677	DNA binding
0.41	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.41	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.39	GO:0017025	TBP-class protein binding
0.39	GO:0004402	histone acetyltransferase activity
0.37	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding

0.72	GO:0005669	transcription factor TFIID complex
0.38	GO:0035102	PRC1 complex
0.36	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.56

GO:0004674

sp|P51140|DSH_DROME
Segment polarity protein dishevelled
Search

0.80	Segment polarity protein dishevelled

0.77	GO:0016055	Wnt signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.54	GO:0090163	establishment of epithelial cell planar polarity
0.53	GO:0048076	regulation of compound eye pigmentation
0.53	GO:0016201	synaptic target inhibition
0.53	GO:0035309	wing and notum subfield formation
0.53	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.53	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.52	GO:1902669	positive regulation of axon guidance
0.52	GO:0035159	regulation of tube length, open tracheal system

0.52	GO:0070300	phosphatidic acid binding
0.51	GO:0030159	receptor signaling complex scaffold activity
0.51	GO:0005112	Notch binding
0.47	GO:0019904	protein domain specific binding
0.39	GO:0005109	frizzled binding

0.51	GO:0045179	apical cortex
0.40	GO:0005886	plasma membrane
0.36	GO:0005829	cytosol
0.36	GO:0005576	extracellular region
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P51406|BYS_DROME
Bystin
Search

0.77	Bystin like

0.71	GO:0001829	trophectodermal cell differentiation
0.68	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.66	GO:0008283	cell proliferation
0.38	GO:0007155	cell adhesion
0.38	GO:0007565	female pregnancy
0.38	GO:0071347	cellular response to interleukin-1
0.37	GO:0071222	cellular response to lipopolysaccharide
0.37	GO:1902476	chloride transmembrane transport
0.37	GO:0071363	cellular response to growth factor stimulus
0.37	GO:0007420	brain development

0.37	GO:0005254	chloride channel activity
0.36	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.67	GO:0045177	apical part of cell
0.63	GO:0005730	nucleolus
0.44	GO:0005737	cytoplasm
0.38	GO:0034707	chloride channel complex
0.36	GO:0005874	microtubule
0.36	GO:0005654	nucleoplasm
0.35	GO:0042995	cell projection

sp|P51521|OVO_DROME
Protein ovo
Search

0.59	GO:0070896	positive regulation of transposon integration
0.57	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.57	GO:0018992	germ-line sex determination
0.56	GO:0035017	cuticle pattern formation
0.56	GO:0048067	cuticle pigmentation
0.56	GO:0035316	non-sensory hair organization
0.56	GO:0008343	adult feeding behavior
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0007010	cytoskeleton organization

0.51	GO:0003676	nucleic acid binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0046872	metal ion binding

0.44	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm

sp|P51592|HYD_DROME
E3 ubiquitin-protein ligase hyd
Search

0.76	E3 ubiquitin-protein ligase hyd

0.70	GO:0016567	protein ubiquitination
0.64	GO:0007446	imaginal disc growth
0.63	GO:0007455	eye-antennal disc morphogenesis
0.63	GO:0007112	male meiosis cytokinesis
0.62	GO:0007289	spermatid nucleus differentiation
0.60	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.60	GO:0008585	female gonad development
0.59	GO:0035220	wing disc development
0.41	GO:0045879	negative regulation of smoothened signaling pathway
0.40	GO:0048749	compound eye development

0.78	GO:0043130	ubiquitin binding
0.71	GO:0004842	ubiquitin-protein transferase activity
0.61	GO:0008270	zinc ion binding
0.57	GO:0003723	RNA binding
0.49	GO:0016874	ligase activity
0.40	GO:0061659	ubiquitin-like protein ligase activity

0.47	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm

0.49	EC:6	GO:0016874
0.71	KEGG:R03876	GO:0004842

sp|P51905|SC6A4_DROME
Sodium-dependent serotonin transporter
Search

0.49	Sodium-and chloride-dependent GABA transporter

0.76	GO:0006836	neurotransmitter transport
0.63	GO:0015844	monoamine transport
0.58	GO:0015850	organic hydroxy compound transport
0.56	GO:0015696	ammonium transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0090067	regulation of thalamus size
0.52	GO:0001505	regulation of neurotransmitter levels
0.51	GO:0098657	import into cell
0.50	GO:0051649	establishment of localization in cell
0.48	GO:0046621	negative regulation of organ growth

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.64	GO:0015222	serotonin transmembrane transporter activity
0.49	GO:0050998	nitric-oxide synthase binding
0.48	GO:0005329	dopamine transmembrane transporter activity
0.46	GO:0005261	cation channel activity
0.46	GO:0017137	Rab GTPase binding
0.36	GO:0019811	cocaine binding
0.36	GO:0051015	actin filament binding
0.35	GO:0017075	syntaxin-1 binding
0.35	GO:0017022	myosin binding

0.55	GO:0098793	presynapse
0.51	GO:0043005	neuron projection
0.47	GO:0005887	integral component of plasma membrane
0.47	GO:0120038	plasma membrane bounded cell projection part
0.46	GO:0045121	membrane raft
0.42	GO:0005829	cytosol
0.42	GO:0012505	endomembrane system
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0098588	bounding membrane of organelle

sp|P52029|G6PI_DROME
Glucose-6-phosphate isomerase
Search

PGI

0.53	Glucose-6-phosphate isomerase

0.73	GO:0019319	hexose biosynthetic process
0.71	GO:0006006	glucose metabolic process
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.46	GO:0042593	glucose homeostasis

0.78

GO:0004347

glucose-6-phosphate isomerase activity

0.33

GO:0005737

cytoplasm

0.78

EC:5.3.1.9

GO:0004347

sp|P52034|PFKA_DROME
ATP-dependent 6-phosphofructokinase
Search

0.45	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.35	GO:0007525	somatic muscle development
0.35	GO:0009744	response to sucrose
0.35	GO:0007520	myoblast fusion
0.35	GO:0042593	glucose homeostasis
0.33	GO:0046835	carbohydrate phosphorylation

0.79	GO:0003872	6-phosphofructokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding

0.49	GO:0005737	cytoplasm
0.34	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.30	GO:0016020	membrane

0.79

EC:2.7.1.11

GO:0003872

sp|P52168|PNR_DROME
GATA-binding factor A
Search

0.69	GATA transcription factor GATAd

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0007510	cardioblast cell fate determination
0.52	GO:0061320	pericardial nephrocyte differentiation
0.50	GO:0002805	regulation of antimicrobial peptide biosynthetic process
0.50	GO:0048542	lymph gland development
0.50	GO:0022416	chaeta development
0.49	GO:0035050	embryonic heart tube development
0.49	GO:0060047	heart contraction

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001103	RNA polymerase II repressing transcription factor binding
0.45	GO:0046982	protein heterodimerization activity
0.41	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0003682	chromatin binding
0.39	GO:0003690	double-stranded DNA binding
0.38	GO:0070410	co-SMAD binding
0.36	GO:0003713	transcription coactivator activity

0.43	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome

sp|P52172|SRP_DROME
Box A-binding factor
Search

LOC108096858

0.95	Box A-binding factor

0.61	GO:0046665	amnioserosa maintenance
0.61	GO:0007516	hemocyte development
0.61	GO:0007503	fat body development
0.60	GO:0035162	embryonic hemopoiesis
0.60	GO:0007390	germ-band shortening
0.59	GO:0035167	larval lymph gland hemopoiesis
0.59	GO:0001710	mesodermal cell fate commitment
0.58	GO:0008354	germ cell migration
0.57	GO:0007435	salivary gland morphogenesis
0.57	GO:2001141	regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0001085	RNA polymerase II transcription factor binding
0.45	GO:0003682	chromatin binding
0.43	GO:0003690	double-stranded DNA binding
0.43	GO:0070742	C2H2 zinc finger domain binding
0.42	GO:0008301	DNA binding, bending
0.41	GO:0002039	p53 binding

0.44	GO:0005667	transcription factor complex
0.42	GO:0005634	nucleus
0.41	GO:0017053	transcriptional repressor complex
0.39	GO:0032993	protein-DNA complex
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0005694	chromosome
0.32	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.33

GO:0004222

sp|P52295|IMA_DROME
Importin subunit alpha
Search

0.61	Importin subunit alpha

0.80	GO:0006606	protein import into nucleus
0.51	GO:0007301	female germline ring canal formation
0.50	GO:0042332	gravitaxis
0.50	GO:0048542	lymph gland development
0.50	GO:0007291	sperm individualization
0.33	GO:0006468	protein phosphorylation

0.83	GO:0061608	nuclear import signal receptor activity
0.69	GO:0008565	protein transporter activity
0.44	GO:0008139	nuclear localization sequence binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.39	GO:0012505	endomembrane system
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0031967	organelle envelope
0.37	GO:0043234	protein complex

sp|P52302|MBN_DROME
Protein lethal(3)malignant blood neoplasm 1
Search

0.89	Lethal (3) malignant blood neoplasm, isoform E

0.51	GO:0040003	chitin-based cuticle development
0.39	GO:0018106	peptidyl-histidine phosphorylation
0.37	GO:0000160	phosphorelay signal transduction system
0.35	GO:0001957	intramembranous ossification
0.33	GO:0042255	ribosome assembly
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.77	GO:0042302	structural constituent of cuticle
0.38	GO:0004673	protein histidine kinase activity
0.37	GO:0004871	signal transducer activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005199	structural constituent of cell wall
0.34	GO:0004004	ATP-dependent RNA helicase activity
0.32	GO:0003676	nucleic acid binding

0.48	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0031012	extracellular matrix
0.39	GO:0005886	plasma membrane
0.33	GO:0005618	cell wall
0.30	GO:0016021	integral component of membrane

0.38

EC:2.7.13.3

GO:0004673

sp|P52304|POLO_DROME
Serine/threonine-protein kinase polo
Search

0.57	Serine threonine-protein kinase polo

0.63	GO:0006468	protein phosphorylation
0.53	GO:0048600	oocyte fate commitment
0.52	GO:0030954	astral microtubule nucleation
0.52	GO:0030726	male germline ring canal formation
0.52	GO:0035044	sperm aster formation
0.52	GO:0007344	pronuclear fusion
0.52	GO:0007058	spindle assembly involved in female meiosis II
0.51	GO:0051257	meiotic spindle midzone assembly
0.51	GO:0035046	pronuclear migration
0.50	GO:0007406	negative regulation of neuroblast proliferation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0004605	phosphatidate cytidylyltransferase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0019001	guanyl nucleotide binding

0.49	GO:0005828	kinetochore microtubule
0.49	GO:1990023	mitotic spindle midzone
0.48	GO:0030496	midbody
0.48	GO:0005814	centriole
0.47	GO:0000940	condensed chromosome outer kinetochore
0.47	GO:0000922	spindle pole
0.47	GO:0005813	centrosome
0.46	GO:0005635	nuclear envelope
0.30	GO:0016020	membrane

0.34

EC:2.7.7.41

GO:0004605

sp|P52485|UBCD2_DROME
Ubiquitin-conjugating enzyme E2-24 kDa
Search

UBCD2

0.54	Ubiquitin-conjugating enzyme

0.47	GO:0070979	protein K11-linked ubiquitination
0.46	GO:0070534	protein K63-linked ubiquitination
0.46	GO:0070936	protein K48-linked ubiquitination
0.41	GO:0019915	lipid storage
0.35	GO:0040008	regulation of growth
0.34	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.34	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0061631	ubiquitin conjugating enzyme activity
0.37	GO:0016874	ligase activity
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0005515	protein binding

0.39	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0030687	preribosome, large subunit precursor
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016874

sp|P52486|UBCD4_DROME
Ubiquitin-conjugating enzyme E2-22 kDa
Search

0.52	Ubiquitin protein ligase

0.49	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.49	GO:0010994	free ubiquitin chain polymerization
0.49	GO:0000209	protein polyubiquitination
0.49	GO:0035458	cellular response to interferon-beta
0.48	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.47	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.41	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0034450	ubiquitin-ubiquitin ligase activity
0.46	GO:0070628	proteasome binding
0.37	GO:0016874	ligase activity

0.49	GO:0032433	filopodium tip
0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37

GO:0016874

sp|P52487|UBC84_DROME
Ubiquitin-conjugating enzyme E2-18 kDa
Search

0.55	Ubiquitin-conjugating enzyme

0.48	GO:0000209	protein polyubiquitination
0.46	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.46	GO:0071385	cellular response to glucocorticoid stimulus
0.45	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.44	GO:1903955	positive regulation of protein targeting to mitochondrion
0.44	GO:0044770	cell cycle phase transition
0.44	GO:0008283	cell proliferation
0.38	GO:0048557	embryonic digestive tract morphogenesis
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:1903506	regulation of nucleic acid-templated transcription

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0061631	ubiquitin conjugating enzyme activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0097027	ubiquitin-protein transferase activator activity
0.43	GO:0003713	transcription coactivator activity
0.38	GO:0016874	ligase activity
0.35	GO:0050662	coenzyme binding
0.34	GO:0016491	oxidoreductase activity

0.39	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome
0.33	GO:0098793	presynapse
0.33	GO:0000151	ubiquitin ligase complex
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.38

GO:0016874

sp|P52654|TF2AA_DROME
Transcription initiation factor IIA subunit 1
Search

LOC108088537

0.84	Transcription initiation factor IIA subunit

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.60	GO:0006413	translational initiation
0.50	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0030100	regulation of endocytosis
0.33	GO:0006897	endocytosis

0.61	GO:0003743	translation initiation factor activity
0.54	GO:0001128	RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly
0.54	GO:0001094	TFIID-class transcription factor binding
0.53	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.50	GO:0017025	TBP-class protein binding

0.83	GO:0005672	transcription factor TFIIA complex
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P52656|T2AG_DROME
Transcription initiation factor IIA subunit 2
Search

0.73	Transcription initiation factor IIA subunit 2

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.59	GO:0006413	translational initiation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.49	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.46	GO:0051254	positive regulation of RNA metabolic process
0.46	GO:0010557	positive regulation of macromolecule biosynthetic process
0.46	GO:0031328	positive regulation of cellular biosynthetic process
0.42	GO:0044093	positive regulation of molecular function

0.59	GO:0003743	translation initiation factor activity
0.48	GO:0003713	transcription coactivator activity
0.45	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.45	GO:0017025	TBP-class protein binding
0.45	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.43	GO:0001103	RNA polymerase II repressing transcription factor binding
0.43	GO:0001104	RNA polymerase II transcription cofactor activity
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.35	GO:0008146	sulfotransferase activity

0.83	GO:0005672	transcription factor TFIIA complex
0.42	GO:0005669	transcription factor TFIID complex
0.40	GO:0030054	cell junction
0.35	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:2.8.2

GO:0008146

sp|P52905|TRYI_DROME
Trypsin iota
Search

0.45	trypsin epsilon

0.61	GO:0006508	proteolysis
0.36	GO:0007596	blood coagulation
0.35	GO:0006898	receptor-mediated endocytosis
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006956	complement activation
0.33	GO:0040008	regulation of growth
0.33	GO:0006629	lipid metabolic process
0.32	GO:0000413	protein peptidyl-prolyl isomerization
0.31	GO:0055114	oxidation-reduction process

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005044	scavenger receptor activity
0.36	GO:0004222	metalloendopeptidase activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0016500	protein-hormone receptor activity
0.34	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.32	GO:0003723	RNA binding
0.31	GO:0016491	oxidoreductase activity

0.42	GO:0005576	extracellular region
0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0005737	cytoplasm
0.33	GO:0009986	cell surface
0.33	GO:0031982	vesicle

0.69

GO:0004252

sp|P53034|RFC2_DROME
Replication factor C subunit 2
Search

RFC2

0.73	Replication factor C subunit

0.65	GO:0006260	DNA replication
0.46	GO:0000076	DNA replication checkpoint
0.45	GO:1900262	regulation of DNA-directed DNA polymerase activity
0.44	GO:0000077	DNA damage checkpoint
0.44	GO:2000573	positive regulation of DNA biosynthetic process
0.42	GO:0051347	positive regulation of transferase activity
0.39	GO:0006281	DNA repair
0.35	GO:0016321	female meiosis chromosome segregation
0.35	GO:0006468	protein phosphorylation
0.35	GO:0007076	mitotic chromosome condensation

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0033170	protein-DNA loading ATPase activity
0.44	GO:0043142	single-stranded DNA-dependent ATPase activity
0.40	GO:0019899	enzyme binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding

0.47	GO:0005663	DNA replication factor C complex
0.46	GO:0031391	Elg1 RFC-like complex
0.43	GO:0031390	Ctf18 RFC-like complex
0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.36

GO:0004674

sp|P53403|GTR3_DROME
Glucose transporter type 3
Search

0.87	Glucose transporter type 3

0.55	GO:0055085	transmembrane transport
0.47	GO:0008643	carbohydrate transport
0.42	GO:0015747	urate transport
0.41	GO:0046415	urate metabolic process
0.38	GO:0015992	proton transport
0.32	GO:0055114	oxidation-reduction process

0.57	GO:0022857	transmembrane transporter activity
0.41	GO:0005536	glucose binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.39	GO:0005887	integral component of plasma membrane
0.35	GO:0005635	nuclear envelope

0.34

GO:0032440

sp|P53501|ACT3_DROME
Actin-57B
Search

0.46	Muscle actin

0.47	GO:0098529	neuromuscular junction development, skeletal muscle fiber
0.43	GO:0043486	histone exchange
0.43	GO:0050807	regulation of synapse organization
0.43	GO:0000281	mitotic cytokinesis
0.42	GO:0016573	histone acetylation
0.36	GO:0007010	cytoskeleton organization
0.34	GO:0007507	heart development

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005200	structural constituent of cytoskeleton

0.42	GO:0035267	NuA4 histone acetyltransferase complex
0.39	GO:0005856	cytoskeleton
0.36	GO:0099512	supramolecular fiber
0.34	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P53624|MA1A1_DROME
Mannosyl-oligosaccharide alpha-1,2-mannosidase IA
Search

0.47	Mannosyl-oligosaccharide alpha-1,2-mannosidase IA

0.42	GO:0006491	N-glycan processing
0.37	GO:0035010	encapsulation of foreign target
0.36	GO:0072347	response to anesthetic
0.36	GO:0008340	determination of adult lifespan
0.35	GO:0006486	protein glycosylation
0.33	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.82	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.70	GO:0005509	calcium ion binding
0.34	GO:0005549	odorant binding
0.33	GO:0004984	olfactory receptor activity

0.40	GO:0000139	Golgi membrane
0.39	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.82	EC:3.2.1.113	GO:0004571
0.82	KEGG:R05982 KEGG:R06722	GO:0004571

sp|P53777|MLP1_DROME
Muscle LIM protein 1
Search

0.60	Muscle LIM protein 1

0.44	GO:0030239	myofibril assembly
0.44	GO:0060537	muscle tissue development
0.43	GO:0090175	regulation of establishment of planar polarity
0.37	GO:0035995	detection of muscle stretch
0.37	GO:0003300	cardiac muscle hypertrophy
0.36	GO:0048513	animal organ development
0.36	GO:0060048	cardiac muscle contraction
0.35	GO:0002026	regulation of the force of heart contraction
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0033365	protein localization to organelle

0.54	GO:0046872	metal ion binding
0.45	GO:0008307	structural constituent of muscle
0.37	GO:0031433	telethonin binding
0.35	GO:0042802	identical protein binding
0.35	GO:0042805	actinin binding

0.45	GO:0030018	Z disc
0.41	GO:0015629	actin cytoskeleton
0.38	GO:0005634	nucleus

sp|P53997|SET_DROME
Protein SET
Search

0.83	Template-activating factor I

0.79	GO:0006334	nucleosome assembly
0.36	GO:0048884	neuromast development
0.36	GO:0043524	negative regulation of neuron apoptotic process
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0035067	negative regulation of histone acetylation
0.34	GO:0031498	chromatin disassembly
0.34	GO:0032986	protein-DNA complex disassembly
0.34	GO:0043488	regulation of mRNA stability
0.34	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.34	GO:0006030	chitin metabolic process

0.37	GO:0005509	calcium ion binding
0.34	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0042393	histone binding
0.34	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.34	GO:0008061	chitin binding
0.33	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0005811	lipid droplet
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005576	extracellular region

sp|P54185|OBA5_DROME
Putative odorant-binding protein A5
Search

0.48	Phosphatidylethanolamine-binding protein 4 (inferred by orthology to a human protein)

0.62	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P54191|OB69A_DROME
General odorant-binding protein 69a
Search

OBP69A

0.97	General odorant-binding protein 69a

0.44	GO:0007608	sensory perception of smell
0.42	GO:0010469	regulation of receptor activity

0.80	GO:0005549	odorant binding
0.50	GO:0008145	phenylalkylamine binding
0.43	GO:0005179	hormone activity

0.44	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P54192|OB19D_DROME
General odorant-binding protein 19d
Search

OBP19D

0.97	General odorant-binding protein 19d

0.42

GO:0007608

sensory perception of smell

0.80

GO:0005549

odorant binding

0.41	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|P54193|OB83A_DROME
General odorant-binding protein 83a
Search

0.79	Olfactory Specific F

0.36

GO:0007608

sensory perception of smell

0.80

GO:0005549

odorant binding

0.36	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|P54194|OB84A_DROME
General odorant-binding protein 84a
Search

OBP84A

0.97	General odorant-binding protein 84a

0.42

GO:0007606

sensory perception of chemical stimulus

0.80

GO:0005549

odorant binding

0.40	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P54195|OB28A_DROME
General odorant-binding protein 28a
Search

0.66	General odorant-binding protein 28a

0.41

GO:0007608

sensory perception of smell

0.80

GO:0005549

odorant binding

0.40	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|P54269|CAUP_DROME
Homeobox protein caupolican
Search

0.77	Homeobox protein caupolican

0.61	GO:0001745	compound eye morphogenesis
0.61	GO:0007476	imaginal disc-derived wing morphogenesis
0.61	GO:0042693	muscle cell fate commitment
0.59	GO:0045926	negative regulation of growth
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0003002	regionalization
0.50	GO:0007346	regulation of mitotic cell cycle
0.48	GO:0048859	formation of anatomical boundary

0.64	GO:0043565	sequence-specific DNA binding
0.47	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.41	GO:0042803	protein homodimerization activity
0.36	GO:0005057	signal transducer activity, downstream of receptor

0.61	GO:0005634	nucleus
0.34	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

sp|P54350|WEE1_DROME
Wee1-like protein kinase
Search

0.88	Putative mitosis inhibitor protein kinase (Fragment)

0.67	GO:0018108	peptidyl-tyrosine phosphorylation
0.66	GO:0000278	mitotic cell cycle
0.56	GO:0051299	centrosome separation
0.56	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.55	GO:0051642	centrosome localization
0.53	GO:0051225	spindle assembly
0.51	GO:0045930	negative regulation of mitotic cell cycle
0.51	GO:0000075	cell cycle checkpoint
0.38	GO:0001700	embryonic development via the syncytial blastoderm
0.35	GO:0051301	cell division

0.71	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.57	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0005515	protein binding

0.55	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.71

EC:2.7.10.2

GO:0004715

sp|P54351|NSF2_DROME
Vesicle-fusing ATPase 2
Search

0.72	N-ethylmaleimide-sensitive factor

0.53	GO:0007274	neuromuscular synaptic transmission
0.48	GO:0060439	trachea morphogenesis
0.47	GO:0035494	SNARE complex disassembly
0.47	GO:0090160	Golgi to lysosome transport
0.47	GO:1900073	regulation of neuromuscular synaptic transmission
0.47	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.47	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane
0.47	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.47	GO:0070050	neuron cellular homeostasis
0.45	GO:0007030	Golgi organization

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016887	ATPase activity
0.35	GO:0052689	carboxylic ester hydrolase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0003676	nucleic acid binding

0.48	GO:0098527	neuromuscular junction of somatic muscle
0.46	GO:0043195	terminal bouton
0.45	GO:0008021	synaptic vesicle
0.41	GO:0005829	cytosol
0.34	GO:0005576	extracellular region
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.36	EC:3.6.1.3	GO:0016887
0.35	KEGG:R00630	GO:0052689

sp|P54352|EAS_DROME
Ethanolamine kinase
Search

0.43	Ethanolamine kinase

0.55	GO:0016310	phosphorylation
0.54	GO:0006646	phosphatidylethanolamine biosynthetic process
0.41	GO:0006657	CDP-choline pathway
0.40	GO:0046959	habituation
0.40	GO:0007638	mechanosensory behavior
0.40	GO:0055059	asymmetric neuroblast division
0.39	GO:0016319	mushroom body development
0.39	GO:0007616	long-term memory
0.39	GO:0008306	associative learning
0.39	GO:0001666	response to hypoxia

0.60	GO:0004305	ethanolamine kinase activity
0.41	GO:0004103	choline kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.60	EC:2.7.1.82	GO:0004305
0.60	KEGG:R01468	GO:0004305

sp|P54353|DOD_DROME
Putative peptidyl-prolyl cis-trans isomerase dodo
Search

0.49	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.50	GO:1904059	regulation of locomotor rhythm
0.48	GO:0007173	epidermal growth factor receptor signaling pathway
0.37	GO:2000749	positive regulation of chromatin silencing at rDNA
0.37	GO:0031064	negative regulation of histone deacetylation
0.37	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.37	GO:0080182	histone H3-K4 trimethylation
0.37	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain
0.36	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.36	GO:0035307	positive regulation of protein dephosphorylation

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0000993	RNA polymerase II core binding
0.34	GO:0008378	galactosyltransferase activity

0.40	GO:0005634	nucleus
0.33	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.72

EC:5.2.1.8

GO:0003755

sp|P54356|TSG_DROME
Protein twisted gastrulation
Search

0.68	Twisted gastrulation protein-A

0.66	GO:0007362	terminal region determination
0.66	GO:0008293	torso signaling pathway
0.66	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.62	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus
0.60	GO:0007630	jump response
0.56	GO:0048636	positive regulation of muscle organ development
0.55	GO:0010629	negative regulation of gene expression
0.52	GO:0007378	amnioserosa formation
0.47	GO:0009953	dorsal/ventral pattern formation
0.46	GO:0009967	positive regulation of signal transduction

0.61	GO:0008201	heparin binding
0.39	GO:0050431	transforming growth factor beta binding

0.53	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|P54357|MLC2_DROME
Myosin-2 essential light chain
Search

0.83	Myosin II essential light chain

0.35	GO:0030048	actin filament-based movement
0.35	GO:0043086	negative regulation of catalytic activity
0.33	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.36	GO:0008073	ornithine decarboxylase inhibitor activity
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.35	GO:0032036	myosin heavy chain binding
0.32	GO:0003676	nucleic acid binding

0.36	GO:0031477	myosin VII complex
0.36	GO:0031476	myosin VI complex
0.35	GO:0031475	myosin V complex
0.35	GO:0016460	myosin II complex
0.33	GO:0005829	cytosol

0.36

GO:0032440

sp|P54358|DPOD1_DROME
DNA polymerase delta catalytic subunit
Search

0.48	DNA polymerase delta catalytic subunit

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.37	GO:0006287	base-excision repair, gap-filling
0.37	GO:0006297	nucleotide-excision repair, DNA gap filling

0.72	GO:0008408	3'-5' exonuclease activity
0.71	GO:0003887	DNA-directed DNA polymerase activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.43	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters

0.60	GO:0005634	nucleus
0.43	GO:0030894	replisome
0.42	GO:0042575	DNA polymerase complex
0.41	GO:0031974	membrane-enclosed lumen

0.71

GO:0003887

sp|P54359|SEPT2_DROME
Septin-2
Search

0.63

Septin

0.49	GO:0007444	imaginal disc development
0.48	GO:0007295	growth of a germarium-derived egg chamber
0.46	GO:0051726	regulation of cell cycle
0.45	GO:0000281	mitotic cytokinesis
0.35	GO:0007349	cellularization
0.34	GO:0007283	spermatogenesis

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042803	protein homodimerization activity
0.41	GO:0003924	GTPase activity

0.48	GO:0031105	septin complex
0.37	GO:0005940	septin ring
0.35	GO:0005819	spindle
0.35	GO:0032173	septin collar
0.35	GO:0097227	sperm annulus
0.34	GO:0032154	cleavage furrow
0.34	GO:0043679	axon terminus
0.34	GO:0030496	midbody
0.34	GO:0008021	synaptic vesicle
0.34	GO:0000777	condensed chromosome kinetochore

sp|P54360|FOJO_DROME
Extracellular serine/threonine protein kinase four-jointed
Search

0.87	Extracellular serine/threonine protein kinase four-jointed

0.66	GO:0007446	imaginal disc growth
0.65	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.65	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.64	GO:0044719	regulation of imaginal disc-derived wing size
0.64	GO:0035159	regulation of tube length, open tracheal system
0.64	GO:0045198	establishment of epithelial cell apical/basal polarity
0.64	GO:0007474	imaginal disc-derived wing vein specification
0.63	GO:0042067	establishment of ommatidial planar polarity
0.60	GO:0043393	regulation of protein binding
0.57	GO:0007267	cell-cell signaling

0.62	GO:0017147	Wnt-protein binding
0.50	GO:0004672	protein kinase activity

0.45	GO:0005886	plasma membrane
0.43	GO:0005615	extracellular space
0.39	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

sp|P54361|OAZ_DROME
Ornithine decarboxylase antizyme
Search

ODA

0.74	Ornithine decarboxylase antizyme

0.72	GO:0043086	negative regulation of catalytic activity
0.55	GO:0006595	polyamine metabolic process
0.50	GO:1902268	negative regulation of polyamine transmembrane transport
0.49	GO:0045732	positive regulation of protein catabolic process
0.47	GO:0090316	positive regulation of intracellular protein transport
0.37	GO:0007275	multicellular organism development
0.35	GO:0042401	cellular biogenic amine biosynthetic process
0.33	GO:0006521	regulation of cellular amino acid metabolic process
0.33	GO:0007165	signal transduction
0.32	GO:2001141	regulation of RNA biosynthetic process

0.85	GO:0008073	ornithine decarboxylase inhibitor activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0008270	zinc ion binding

0.51	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P54362|AP3D_DROME
AP-3 complex subunit delta
Search

0.54	Cystathionine beta-synthase

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.54	GO:0048072	compound eye pigmentation
0.54	GO:0008057	eye pigment granule organization
0.53	GO:0033060	ocellus pigmentation
0.53	GO:0007220	Notch receptor processing
0.53	GO:0006726	eye pigment biosynthetic process
0.51	GO:0008340	determination of adult lifespan
0.51	GO:0060967	negative regulation of gene silencing by RNA
0.47	GO:0044550	secondary metabolite biosynthetic process

0.35	GO:0004122	cystathionine beta-synthase activity
0.35	GO:0008565	protein transporter activity
0.32	GO:0016301	kinase activity

0.83	GO:0030123	AP-3 adaptor complex
0.62	GO:0005794	Golgi apparatus
0.50	GO:0005770	late endosome
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0031984	organelle subcompartment
0.36	GO:0030665	clathrin-coated vesicle membrane
0.36	GO:0005798	Golgi-associated vesicle
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.35

EC:4.2.1.22

GO:0004122

sp|P54366|GSC_DROME
Homeobox protein goosecoid
Search

0.66	Homeobox protein goosecoid

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0007275	multicellular organism development
0.34	GO:0048033	heme o metabolic process
0.33	GO:0006783	heme biosynthetic process

0.62	GO:0043565	sequence-specific DNA binding
0.39	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0008495	protoheme IX farnesyltransferase activity
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:2.5.1

GO:0008495

sp|P54367|KC1A_DROME
Casein kinase I isoform alpha
Search

CSNK1A1

0.49	Casein kinase I alpha S

0.63	GO:0006468	protein phosphorylation
0.47	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.44	GO:0018209	peptidyl-serine modification
0.44	GO:0045879	negative regulation of smoothened signaling pathway
0.44	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.43	GO:0000902	cell morphogenesis
0.43	GO:0042593	glucose homeostasis
0.42	GO:0016055	Wnt signaling pathway
0.42	GO:0045104	intermediate filament cytoskeleton organization
0.41	GO:0006909	phagocytosis

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.34	GO:0042277	peptide binding
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0000287	magnesium ion binding

0.42	GO:0005634	nucleus
0.41	GO:0030877	beta-catenin destruction complex
0.41	GO:0045095	keratin filament
0.40	GO:0036064	ciliary basal body
0.39	GO:0005813	centrosome
0.38	GO:0005829	cytosol
0.38	GO:0000777	condensed chromosome kinetochore
0.38	GO:0043233	organelle lumen
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0000139	Golgi membrane

0.67

GO:0004674

sp|P54385|DHE3_DROME
Glutamate dehydrogenase, mitochondrial
Search

0.40	Glutamate dehydrogenase

0.60	GO:0006520	cellular amino acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.46	GO:0006734	NADH metabolic process
0.41	GO:0043648	dicarboxylic acid metabolic process
0.36	GO:0046693	sperm storage
0.33	GO:0046395	carboxylic acid catabolic process
0.33	GO:1901565	organonitrogen compound catabolic process

0.76	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.42	GO:0042802	identical protein binding
0.34	GO:0036439	glycerol-3-phosphate dehydrogenase [NADP+] activity
0.34	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
0.34	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.39	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.76	EC:1.4.1	GO:0016639
0.34	KEGG:R00844	GO:0036439

sp|P54397|FKB39_DROME
39 kDa FK506-binding nuclear protein
Search

0.28	Peptidylprolyl isomerase

0.79	GO:0000412	histone peptidyl-prolyl isomerization
0.59	GO:0035626	juvenile hormone mediated signaling pathway
0.56	GO:0016242	negative regulation of macroautophagy
0.39	GO:0006457	protein folding
0.35	GO:0051598	meiotic recombination checkpoint
0.34	GO:0006334	nucleosome assembly
0.34	GO:0071897	DNA biosynthetic process
0.34	GO:0043086	negative regulation of catalytic activity
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006814	sodium ion transport

0.78	GO:0005528	FK506 binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.61	GO:0070594	juvenile hormone response element binding
0.36	GO:0005515	protein binding
0.35	GO:0008073	ornithine decarboxylase inhibitor activity
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0009678	hydrogen-translocating pyrophosphatase activity
0.33	GO:0004427	inorganic diphosphatase activity
0.33	GO:0030955	potassium ion binding
0.33	GO:0004965	G-protein coupled GABA receptor activity

0.67	GO:0005730	nucleolus
0.54	GO:0000792	heterochromatin
0.32	GO:0005887	integral component of plasma membrane

0.72	EC:5.2.1.8	GO:0003755
0.33	KEGG:R00004	GO:0004427

sp|P54398|FBP2_DROME
Fat body protein 2
Search

0.97	LOW QUALITY PROTEIN: fat body protein 2

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0006066	alcohol metabolic process
0.32	GO:0006633	fatty acid biosynthetic process

0.80	GO:0004022	alcohol dehydrogenase (NAD) activity
0.37	GO:0045735	nutrient reservoir activity
0.32	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.32	GO:0051287	NAD binding

0.80

EC:1.1.1.1

GO:0004022

sp|P54399|PDI_DROME
Protein disulfide-isomerase
Search

0.48	Protein disulfide-isomerase

0.69	GO:0045454	cell redox homeostasis
0.49	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.48	GO:0019511	peptidyl-proline hydroxylation
0.47	GO:0034976	response to endoplasmic reticulum stress
0.47	GO:0019471	4-hydroxyproline metabolic process
0.46	GO:0046598	positive regulation of viral entry into host cell
0.45	GO:0071456	cellular response to hypoxia
0.40	GO:0006457	protein folding
0.37	GO:0055114	oxidation-reduction process
0.35	GO:0034378	chylomicron assembly

0.82	GO:0003756	protein disulfide isomerase activity
0.48	GO:0031545	peptidyl-proline 4-dioxygenase activity
0.45	GO:0019798	procollagen-proline dioxygenase activity
0.45	GO:0005178	integrin binding
0.44	GO:0015037	peptide disulfide oxidoreductase activity
0.43	GO:0046982	protein heterodimerization activity
0.34	GO:0019899	enzyme binding
0.32	GO:0003723	RNA binding

0.70	GO:0005783	endoplasmic reticulum
0.50	GO:0070732	spindle envelope
0.49	GO:0060187	cell pole
0.48	GO:0045169	fusome
0.46	GO:0043025	neuronal cell body
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005635	nuclear envelope
0.44	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.44	GO:0009897	external side of plasma membrane
0.44	GO:0005615	extracellular space

0.82

EC:5.3.4.1

GO:0003756

sp|P54611|VATE_DROME
V-type proton ATPase subunit E
Search

0.54	Vacuolar ATP synthethase subunit E

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.48	GO:0007430	terminal branching, open tracheal system
0.47	GO:0045176	apical protein localization
0.41	GO:0060036	notochord cell vacuolation
0.41	GO:0033336	caudal fin development
0.40	GO:0031101	fin regeneration
0.39	GO:0060041	retina development in camera-type eye
0.36	GO:0035002	liquid clearance, open tracheal system
0.35	GO:0032790	ribosome disassembly
0.34	GO:0032543	mitochondrial translation

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.41	GO:0008900	potassium:proton exchanging ATPase activity
0.38	GO:0051117	ATPase binding
0.38	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
0.48	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.37	GO:0016324	apical plasma membrane
0.37	GO:0005902	microvillus
0.37	GO:0005768	endosome
0.36	GO:0005829	cytosol
0.35	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.35	GO:0005739	mitochondrion

0.41

EC:3.6.3.10

GO:0008900

sp|P54622|SSBP_DROME
Single-stranded DNA-binding protein, mitochondrial
Search

0.43	Single-stranded DNA-binding protein, mitochondrial

0.66	GO:0006260	DNA replication
0.54	GO:0032042	mitochondrial DNA metabolic process
0.35	GO:0006310	DNA recombination
0.35	GO:0006281	DNA repair

0.74	GO:0003697	single-stranded DNA binding
0.36	GO:0017134	fibroblast growth factor binding

0.54

GO:0000262

mitochondrial chromosome

sp|P54623|CNN_DROME
Centrosomin
Search

0.32	Centrosomin

0.41	GO:0007099	centriole replication
0.41	GO:0046605	regulation of centrosome cycle
0.41	GO:0007279	pole cell formation
0.40	GO:0008594	photoreceptor cell morphogenesis
0.40	GO:0040016	embryonic cleavage
0.40	GO:0016321	female meiosis chromosome segregation
0.40	GO:0007494	midgut development
0.40	GO:0055059	asymmetric neuroblast division
0.40	GO:0007417	central nervous system development
0.39	GO:0007422	peripheral nervous system development

0.41	GO:0003796	lysozyme activity
0.39	GO:0008017	microtubule binding
0.36	GO:0043015	gamma-tubulin binding
0.36	GO:0005516	calmodulin binding
0.36	GO:0019901	protein kinase binding
0.36	GO:0044212	transcription regulatory region DNA binding

0.76	GO:0005815	microtubule organizing center
0.40	GO:0000922	spindle pole
0.39	GO:0031514	motile cilium
0.38	GO:0005875	microtubule associated complex
0.37	GO:0035371	microtubule plus-end
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0072686	mitotic spindle
0.36	GO:0030054	cell junction
0.35	GO:0005794	Golgi apparatus
0.32	GO:0044421	extracellular region part

0.41

GO:0003796

sp|P54631|SCW_DROME
Protein screw
Search

SCREW

0.61	Bone morphogenetic protein (Fragment)

0.76	GO:0010469	regulation of receptor activity
0.60	GO:0007502	digestive tract mesoderm development
0.56	GO:0007389	pattern specification process
0.55	GO:0048608	reproductive structure development
0.54	GO:0045137	development of primary sexual characteristics
0.54	GO:0048513	animal organ development
0.50	GO:0010629	negative regulation of gene expression
0.49	GO:0010562	positive regulation of phosphorus metabolic process
0.49	GO:0031401	positive regulation of protein modification process
0.49	GO:0060395	SMAD protein signal transduction

0.78	GO:0008083	growth factor activity
0.51	GO:0046982	protein heterodimerization activity
0.44	GO:0005160	transforming growth factor beta receptor binding
0.43	GO:0005125	cytokine activity
0.42	GO:0070700	BMP receptor binding
0.36	GO:0008201	heparin binding
0.34	GO:0042803	protein homodimerization activity

0.66	GO:0005576	extracellular region
0.44	GO:0071595	Nem1-Spo7 phosphatase complex
0.35	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P54733|CCNE_DROME
G1/S-specific cyclin-E
Search

0.84	Cyclin E, isoform C

0.60	GO:0000082	G1/S transition of mitotic cell cycle
0.55	GO:0051726	regulation of cell cycle
0.45	GO:0007129	synapsis
0.45	GO:0045859	regulation of protein kinase activity
0.44	GO:0000723	telomere maintenance
0.44	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0016055	Wnt signaling pathway
0.43	GO:1903827	regulation of cellular protein localization
0.43	GO:0006270	DNA replication initiation
0.40	GO:0035736	cell proliferation involved in compound eye morphogenesis

0.47	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.44	GO:0019901	protein kinase binding
0.39	GO:0016301	kinase activity
0.34	GO:0050681	androgen receptor binding
0.33	GO:0003713	transcription coactivator activity
0.33	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.48	GO:0097134	cyclin E1-CDK2 complex
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.33	GO:0015630	microtubule cytoskeleton
0.33	GO:0005829	cytosol

0.47

GO:0016538

sp|P55035|PSMD4_DROME
26S proteasome non-ATPase regulatory subunit 4
Search

0.54	LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 4

0.49	GO:0006511	ubiquitin-dependent protein catabolic process
0.49	GO:0000070	mitotic sister chromatid segregation
0.49	GO:0010498	proteasomal protein catabolic process
0.38	GO:0043248	proteasome assembly
0.37	GO:0008063	Toll signaling pathway
0.37	GO:0007623	circadian rhythm
0.34	GO:0006629	lipid metabolic process
0.33	GO:0006468	protein phosphorylation
0.33	GO:0055114	oxidation-reduction process

0.52	GO:0031624	ubiquitin conjugating enzyme binding
0.43	GO:0008270	zinc ion binding
0.39	GO:0031593	polyubiquitin modification-dependent protein binding
0.36	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.36	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.35	GO:0003995	acyl-CoA dehydrogenase activity
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding

0.71	GO:1905369	endopeptidase complex
0.58	GO:0043234	protein complex
0.44	GO:0044424	intracellular part
0.35	GO:0043233	organelle lumen
0.34	GO:0043227	membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.3.99.3

GO:0003995

sp|P55162|HEM_DROME
Membrane-associated protein Hem
Search

0.88	Membrane-associated protein Hem

0.72	GO:0008407	chaeta morphogenesis
0.71	GO:0033627	cell adhesion mediated by integrin
0.70	GO:0007520	myoblast fusion
0.69	GO:0007528	neuromuscular junction development
0.68	GO:0001764	neuron migration
0.67	GO:0030866	cortical actin cytoskeleton organization
0.65	GO:0007409	axonogenesis
0.64	GO:0007417	central nervous system development
0.61	GO:0030031	cell projection assembly
0.58	GO:0051128	regulation of cellular component organization

0.53	GO:0048365	Rac GTPase binding
0.48	GO:0032403	protein complex binding
0.44	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.44	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0031209	SCAR complex
0.40	GO:0031258	lamellipodium membrane
0.40	GO:0031941	filamentous actin
0.39	GO:0001726	ruffle
0.39	GO:0005925	focal adhesion
0.39	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.44

GO:0032440

sp|P55824|FAF_DROME
Probable ubiquitin carboxyl-terminal hydrolase FAF
Search

0.44	Ubiquitin carboxyl-terminal hydrolase FAF-X

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.57	GO:0035192	nuclear cortical migration
0.57	GO:0008583	mystery cell differentiation
0.53	GO:0007349	cellularization
0.53	GO:0009950	dorsal/ventral axis specification
0.39	GO:0008354	germ cell migration
0.38	GO:0050829	defense response to Gram-negative bacterium
0.38	GO:0048477	oogenesis
0.37	GO:0007601	visual perception

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.76

GO:0036459

sp|P55828|RS20_DROME
40S ribosomal protein S20
Search

RPS20

0.59	Ribosomal protein S20

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis
0.32	GO:0036211	protein modification process

0.64	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0015935	small ribosomal subunit
0.47	GO:0022626	cytosolic ribosome
0.36	GO:0031012	extracellular matrix
0.35	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.33

GO:0004674

sp|P55830|RS3A_DROME
40S ribosomal protein S3a
Search

0.39	Ribosomal protein (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.45	GO:0048477	oogenesis
0.42	GO:0007275	multicellular organism development

0.64

GO:0003735

structural constituent of ribosome

0.72	GO:0022627	cytosolic small ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

sp|P55841|RL14_DROME
60S ribosomal protein L14
Search

RPL14

0.56	Ribosomal protein L14

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0043524	negative regulation of neuron apoptotic process
0.46	GO:0042273	ribosomal large subunit biogenesis
0.39	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.42	GO:0045296	cadherin binding
0.38	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.42	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.35	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.33	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|P55935|RS9_DROME
40S ribosomal protein S9
Search

0.69	Ribosomal protein S9

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.45	GO:0045903	positive regulation of translational fidelity
0.44	GO:0008284	positive regulation of cell proliferation
0.34	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.34	GO:0034660	ncRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0045182	translation regulator activity
0.35	GO:0000213	tRNA-intron endonuclease activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0015935	small ribosomal subunit
0.46	GO:0022626	cytosolic ribosome
0.46	GO:0005730	nucleolus
0.40	GO:0000228	nuclear chromosome
0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.1.27.9

GO:0000213

sp|P55965|BYN_DROME
T-related protein
Search

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0060562	epithelial tube morphogenesis
0.55	GO:0048598	embryonic morphogenesis
0.54	GO:0007494	midgut development
0.54	GO:0072002	Malpighian tubule development
0.54	GO:0007442	hindgut morphogenesis
0.53	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.50	GO:0001102	RNA polymerase II activating transcription factor binding
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.43	GO:0043233	organelle lumen
0.36	GO:0005737	cytoplasm

sp|P56079|CDSA_DROME
Phosphatidate cytidylyltransferase, photoreceptor-specific
Search

0.48	Phosphatidate cytidylyltransferase, photoreceptor-specific

0.78	GO:0016024	CDP-diacylglycerol biosynthetic process
0.48	GO:0043052	thermotaxis
0.48	GO:0016056	rhodopsin mediated signaling pathway
0.48	GO:0007291	sperm individualization
0.47	GO:0010883	regulation of lipid storage
0.46	GO:0019915	lipid storage
0.45	GO:0016049	cell growth
0.40	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway
0.40	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.39	GO:0001525	angiogenesis

0.79	GO:0004605	phosphatidate cytidylyltransferase activity
0.34	GO:0042578	phosphoric ester hydrolase activity
0.33	GO:0008270	zinc ion binding

0.39	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.79

EC:2.7.7.41

GO:0004605

sp|P56175|RCL1_DROME
Probable RNA 3'-terminal phosphate cyclase-like protein
Search

RCL1

0.56	RNA terminal phosphate cyclase like 1

0.67	GO:0042254	ribosome biogenesis
0.62	GO:0006396	RNA processing
0.48	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.47	GO:0016072	rRNA metabolic process
0.38	GO:0006069	ethanol oxidation
0.33	GO:0043085	positive regulation of catalytic activity
0.33	GO:0019538	protein metabolic process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0044260	cellular macromolecule metabolic process

0.48	GO:0003963	RNA-3'-phosphate cyclase activity
0.43	GO:0004521	endoribonuclease activity
0.38	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.36	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0008047	enzyme activator activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding

0.73	GO:0005730	nucleolus
0.35	GO:0005654	nucleoplasm
0.34	GO:0090575	RNA polymerase II transcription factor complex
0.34	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.34	GO:0030686	90S preribosome
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.48	EC:6.5.1.4	GO:0003963
0.38	KEGG:R06983 KEGG:R07140	GO:0051903

sp|P56538|IF6_DROME
Eukaryotic translation initiation factor 6
Search

EIF6

0.69	Eukaryotic translation initiation factor 6

0.79	GO:0042256	mature ribosome assembly
0.75	GO:0042273	ribosomal large subunit biogenesis
0.71	GO:0006413	translational initiation
0.60	GO:0000054	ribosomal subunit export from nucleus
0.43	GO:0045652	regulation of megakaryocyte differentiation
0.43	GO:0006110	regulation of glycolytic process
0.42	GO:0042304	regulation of fatty acid biosynthetic process
0.42	GO:0032868	response to insulin
0.42	GO:2000377	regulation of reactive oxygen species metabolic process
0.42	GO:1902626	assembly of large subunit precursor of preribosome

0.77	GO:0043023	ribosomal large subunit binding
0.74	GO:0043022	ribosome binding
0.72	GO:0003743	translation initiation factor activity
0.33	GO:0005515	protein binding

0.72	GO:0005730	nucleolus
0.48	GO:0005737	cytoplasm
0.43	GO:0005638	lamin filament
0.40	GO:0030687	preribosome, large subunit precursor
0.36	GO:0070062	extracellular exosome
0.35	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|P56544|ACYP1_DROME
Acylphosphatase-1
Search

0.58	Acylphosphatase

0.30	GO:0009987	cellular process
0.30	GO:0008152	metabolic process

0.81	GO:0003998	acylphosphatase activity
0.33	GO:0004659	prenyltransferase activity
0.32	GO:0000287	magnesium ion binding

0.36	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.6.1.7

GO:0003998

sp|P56672|OTP_DROME
Homeobox protein orthopedia
Search

0.89	Homeobox protein orthopedia B

0.67	GO:0007275	multicellular organism development
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.46	GO:2000648	positive regulation of stem cell proliferation
0.46	GO:0060322	head development
0.46	GO:2000179	positive regulation of neural precursor cell proliferation
0.44	GO:0010720	positive regulation of cell development
0.44	GO:0051962	positive regulation of nervous system development
0.43	GO:0030154	cell differentiation

0.62

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P56721|COLL_DROME
Transcription factor collier
Search

0.61	Transcription factor collier

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.41	GO:0051960	regulation of nervous system development
0.41	GO:0060284	regulation of cell development
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0043065	positive regulation of apoptotic process

0.67	GO:0046983	protein dimerization activity
0.59	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.42	GO:0035035	histone acetyltransferase binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.39	GO:0000785	chromatin
0.38	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P58950|GR10A_DROME
Gustatory receptor 10a
Search

0.52	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.58	GO:0007165	signal transduction
0.47	GO:0010037	response to carbon dioxide
0.46	GO:0008049	male courtship behavior
0.45	GO:0007635	chemosensory behavior
0.43	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.61	GO:0004871	signal transducer activity
0.41	GO:0099600	transmembrane receptor activity

0.54	GO:0005886	plasma membrane
0.44	GO:0043025	neuronal cell body
0.44	GO:0030425	dendrite
0.44	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P58951|GR22A_DROME
Putative gustatory receptor 22a
Search

0.56	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction
0.51	GO:0010037	response to carbon dioxide
0.50	GO:0008049	male courtship behavior
0.49	GO:0007635	chemosensory behavior
0.46	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.63	GO:0004871	signal transducer activity
0.44	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.47	GO:0043025	neuronal cell body
0.47	GO:0030425	dendrite
0.47	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P58952|GR22C_DROME
Putative gustatory receptor 22c
Search

0.49	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction
0.58	GO:0010037	response to carbon dioxide
0.57	GO:0008049	male courtship behavior
0.56	GO:0007635	chemosensory behavior
0.51	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.63	GO:0004871	signal transducer activity
0.49	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.54	GO:0043025	neuronal cell body
0.54	GO:0030425	dendrite
0.54	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P58953|GR22E_DROME
Gustatory receptor for bitter taste 22e
Search

0.56	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction
0.50	GO:0010037	response to carbon dioxide
0.49	GO:0008049	male courtship behavior
0.48	GO:0007635	chemosensory behavior
0.45	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.63	GO:0004871	signal transducer activity
0.43	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.47	GO:0043025	neuronal cell body
0.46	GO:0030425	dendrite
0.46	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P58954|GR22F_DROME
Putative gustatory receptor 22f
Search

0.49	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction
0.54	GO:0010037	response to carbon dioxide
0.53	GO:0008049	male courtship behavior
0.52	GO:0007635	chemosensory behavior
0.48	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.64	GO:0004871	signal transducer activity
0.46	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.51	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.50	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P58955|GR36A_DROME
Putative gustatory receptor 36a
Search

0.51	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction
0.56	GO:0010037	response to carbon dioxide
0.55	GO:0008049	male courtship behavior
0.53	GO:0007635	chemosensory behavior
0.49	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.63	GO:0004871	signal transducer activity
0.47	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.52	GO:0043025	neuronal cell body
0.51	GO:0030425	dendrite
0.51	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P58957|G39AB_DROME
Gustatory and pheromone receptor 39a, isoform C
Search

0.44	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.73	GO:0008049	male courtship behavior
0.60	GO:0007165	signal transduction
0.46	GO:0010037	response to carbon dioxide
0.45	GO:0007635	chemosensory behavior
0.42	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.35	GO:0019236	response to pheromone

0.64	GO:0004871	signal transducer activity
0.44	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.44	GO:0043025	neuronal cell body
0.44	GO:0030425	dendrite
0.43	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P58960|GR39B_DROME
Putative gustatory receptor 39b
Search

0.45	Gustatory receptor

0.81	GO:0050909	sensory perception of taste
0.58	GO:0007165	signal transduction
0.51	GO:0010037	response to carbon dioxide
0.50	GO:0008049	male courtship behavior
0.49	GO:0007635	chemosensory behavior
0.46	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.61	GO:0004871	signal transducer activity
0.44	GO:0099600	transmembrane receptor activity

0.54	GO:0005886	plasma membrane
0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.47	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P58961|GR47B_DROME
Putative gustatory receptor 47b
Search

0.41	Gustatory receptor

0.59	GO:0050909	sensory perception of taste
0.49	GO:0010037	response to carbon dioxide
0.48	GO:0008049	male courtship behavior
0.47	GO:0007635	chemosensory behavior
0.46	GO:0007165	signal transduction
0.44	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.49	GO:0033041	sweet taste receptor activity
0.44	GO:0004984	olfactory receptor activity

0.46	GO:0043025	neuronal cell body
0.46	GO:0030425	dendrite
0.46	GO:0030424	axon
0.43	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P58962|GR58A_DROME
Putative gustatory receptor 58a
Search

0.49	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction

0.63	GO:0004871	signal transducer activity
0.45	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P58985|GR59D_DROME
Putative gustatory receptor 59d
Search

0.49	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction
0.53	GO:0010037	response to carbon dioxide
0.52	GO:0008049	male courtship behavior
0.51	GO:0050907	detection of chemical stimulus involved in sensory perception
0.51	GO:0007635	chemosensory behavior
0.47	GO:0007608	sensory perception of smell

0.64	GO:0004871	signal transducer activity
0.49	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.49	GO:0043025	neuronal cell body
0.49	GO:0030425	dendrite
0.49	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P61209|ARF1_DROME
ADP-ribosylation factor 1
Search

0.65	ADP-ribosylation factor B

0.40	GO:0032011	ARF protein signal transduction
0.40	GO:1904801	positive regulation of neuron remodeling
0.40	GO:1990386	mitotic cleavage furrow ingression
0.39	GO:1902036	regulation of hematopoietic stem cell differentiation
0.39	GO:0007112	male meiosis cytokinesis
0.39	GO:0030100	regulation of endocytosis
0.39	GO:0010883	regulation of lipid storage
0.39	GO:0043001	Golgi to plasma membrane protein transport
0.38	GO:0001745	compound eye morphogenesis
0.37	GO:0051050	positive regulation of transport

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003924	GTPase activity

0.45	GO:0005622	intracellular
0.38	GO:0097610	cell surface furrow
0.38	GO:0032155	cell division site part
0.38	GO:0045177	apical part of cell
0.37	GO:0012505	endomembrane system
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0044422	organelle part
0.34	GO:0098793	presynapse
0.30	GO:0031224	intrinsic component of membrane

sp|P61849|NEMS_DROME
Dromyosuppressin
Search

0.88	Leucomyosuppressin

0.83	GO:0010459	negative regulation of heart rate
0.83	GO:0060457	negative regulation of digestive system process
0.82	GO:0045986	negative regulation of smooth muscle contraction
0.77	GO:0008344	adult locomotory behavior
0.75	GO:0007218	neuropeptide signaling pathway
0.43	GO:0010469	regulation of receptor activity

0.80	GO:0071855	neuropeptide receptor binding
0.46	GO:0005184	neuropeptide hormone activity

0.67	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|P61851|SODC_DROME
Superoxide dismutase [Cu-Zn]
Search

SOD

0.52	Cu/Zn-superoxide dismutase

0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.43	GO:0071457	cellular response to ozone
0.43	GO:0071486	cellular response to high light intensity
0.42	GO:0071493	cellular response to UV-B
0.41	GO:0071472	cellular response to salt stress
0.37	GO:0007568	aging

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.35	GO:0042802	identical protein binding
0.35	GO:0030346	protein phosphatase 2B binding
0.34	GO:0048365	Rac GTPase binding
0.34	GO:0046983	protein dimerization activity
0.34	GO:0051087	chaperone binding
0.33	GO:0004601	peroxidase activity

0.41	GO:0005777	peroxisome
0.39	GO:0005773	vacuole
0.36	GO:0005615	extracellular space
0.34	GO:0032839	dendrite cytoplasm
0.34	GO:1904115	axon cytoplasm
0.34	GO:0005829	cytosol
0.34	GO:0043209	myelin sheath
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0043025	neuronal cell body
0.33	GO:0031012	extracellular matrix

0.77	EC:1.15.1.1	GO:0004784
0.33	KEGG:R03532	GO:0004601

sp|P61855|AKH_DROME
Adipokinetic hormone
Search

0.88	Adipokinetic hormone

0.76	GO:0010469	regulation of receptor activity
0.64	GO:0055088	lipid homeostasis
0.63	GO:0042593	glucose homeostasis
0.63	GO:0007218	neuropeptide signaling pathway
0.61	GO:0042594	response to starvation

0.79	GO:0005179	hormone activity
0.75	GO:0097005	adipokinetic hormone receptor binding

0.66

GO:0005576

extracellular region

sp|P61857|TBB2_DROME
Tubulin beta-2 chain
Search

0.57	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.47	GO:0007435	salivary gland morphogenesis
0.35	GO:0016203	muscle attachment
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003725	double-stranded RNA binding
0.33	GO:0004930	G-protein coupled receptor activity

0.73	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P62152|CALM_DROME
Calmodulin
Search

0.48	Calmodulin-A

0.40	GO:0051296	establishment of meiotic spindle orientation
0.39	GO:0016061	regulation of light-activated channel activity
0.39	GO:0043277	apoptotic cell clearance
0.39	GO:0016060	metarhodopsin inactivation
0.38	GO:0072499	photoreceptor cell axon guidance
0.38	GO:0035071	salivary gland cell autophagic cell death
0.38	GO:0016056	rhodopsin mediated signaling pathway
0.38	GO:0042052	rhabdomere development
0.37	GO:0046716	muscle cell cellular homeostasis
0.37	GO:2001259	positive regulation of cation channel activity

0.70	GO:0005509	calcium ion binding
0.39	GO:0070855	myosin VI head/neck binding
0.38	GO:0031489	myosin V binding
0.36	GO:0031418	L-ascorbic acid binding
0.35	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0005506	iron ion binding
0.34	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0003707	steroid hormone receptor activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding

0.40	GO:0072686	mitotic spindle
0.39	GO:0005813	centrosome
0.39	GO:0031476	myosin VI complex
0.38	GO:0031475	myosin V complex
0.38	GO:0016028	rhabdomere
0.37	GO:0031965	nuclear membrane
0.37	GO:0030496	midbody
0.37	GO:0005814	centriole
0.36	GO:0000922	spindle pole
0.34	GO:0071944	cell periphery

0.35

GO:0016705

sp|P80455|RS12_DROME
40S ribosomal protein S12
Search

0.67	40S ribosomal protein S12

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part

sp|P81160|DEJP_DROME
Ductus ejaculatorius peptide 99B
Search

ACP70A

0.97	Sex peptide

0.87	GO:0046008	regulation of female receptivity, post-mating
0.76	GO:0010469	regulation of receptor activity
0.69	GO:0007621	negative regulation of female receptivity
0.67	GO:0018991	oviposition
0.55	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0046662	regulation of oviposition
0.45	GO:0007556	regulation of juvenile hormone metabolic process
0.45	GO:0006718	juvenile hormone biosynthetic process
0.44	GO:0045297	post-mating behavior
0.43	GO:0008343	adult feeding behavior

0.79	GO:0005179	hormone activity
0.61	GO:0001664	G-protein coupled receptor binding

0.66

GO:0005576

extracellular region

sp|P81641|AMYB_DROME
Alpha-amylase B
Search

0.43	Alpha-amylase B

0.60

GO:0005975

carbohydrate metabolic process

0.71	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.70	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding

0.33

GO:0005576

extracellular region

0.70

EC:3.2.1.1

GO:0004556

sp|P81829|LCK_DROME
Leucokinin
Search

0.97	Leucokinin

0.85	GO:2000252	negative regulation of feeding behavior
0.83	GO:0007589	body fluid secretion
0.78	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.72	GO:0010469	regulation of receptor activity
0.47	GO:0007218	neuropeptide signaling pathway

0.85	GO:0008613	diuretic hormone activity
0.81	GO:0005184	neuropeptide hormone activity

0.44	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005623	cell

sp|P81900|KAPR2_DROME
cAMP-dependent protein kinase type II regulatory subunit
Search

0.43	cAMP-dependent protein kinase type II regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.51	GO:0016310	phosphorylation
0.50	GO:0048148	behavioral response to cocaine
0.50	GO:0048149	behavioral response to ethanol
0.50	GO:0045475	locomotor rhythm
0.47	GO:0007411	axon guidance
0.42	GO:0033673	negative regulation of kinase activity
0.40	GO:0001933	negative regulation of protein phosphorylation
0.40	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process

0.85	GO:0008603	cAMP-dependent protein kinase regulator activity
0.84	GO:0030552	cAMP binding
0.53	GO:0016301	kinase activity
0.43	GO:0034236	protein kinase A catalytic subunit binding
0.43	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.42	GO:0060089	molecular transducer activity
0.41	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0019904	protein domain specific binding
0.40	GO:0140096	catalytic activity, acting on a protein

0.84	GO:0005952	cAMP-dependent protein kinase complex
0.43	GO:0031588	nucleotide-activated protein kinase complex
0.42	GO:0044853	plasma membrane raft
0.42	GO:0005930	axoneme
0.41	GO:0005813	centrosome
0.34	GO:0097546	ciliary base
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.41

GO:0016773

sp|P81909|OR22A_DROME
Odorant receptor 22a
Search

0.56	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction
0.43	GO:0042048	olfactory behavior

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.53	GO:0005886	plasma membrane
0.48	GO:0030425	dendrite
0.48	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81910|OR22B_DROME
Odorant receptor 22b
Search

0.58	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction
0.42	GO:0042048	olfactory behavior

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.53	GO:0005886	plasma membrane
0.48	GO:0030425	dendrite
0.48	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81911|OR22C_DROME
Odorant receptor 22c
Search

0.45	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.60	GO:0007165	signal transduction
0.37	GO:0016567	protein ubiquitination

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity
0.37	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0016874	ligase activity

0.52	GO:0005886	plasma membrane
0.43	GO:0030425	dendrite
0.43	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:6	GO:0016874
0.37	KEGG:R03876	GO:0004842

sp|P81912|OR23A_DROME
Odorant receptor 23a
Search

0.48	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.73	GO:0043025	neuronal cell body
0.73	GO:0030425	dendrite
0.56	GO:0005886	plasma membrane
0.47	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81913|OR24A_DROME
Odorant receptor 24a
Search

0.46	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.55	GO:0005886	plasma membrane
0.42	GO:0030425	dendrite
0.42	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81914|OR33A_DROME
Odorant receptor 33a
Search

0.50	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.55	GO:0005886	plasma membrane
0.44	GO:0030425	dendrite
0.44	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81915|OR33B_DROME
Odorant receptor 33b
Search

0.50	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.55	GO:0005886	plasma membrane
0.43	GO:0030425	dendrite
0.42	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81916|OR33C_DROME
Odorant receptor 33c
Search

0.46	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.52	GO:0005886	plasma membrane
0.44	GO:0030425	dendrite
0.43	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81917|OR43A_DROME
Odorant receptor 43a
Search

OR43A

0.51	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction
0.57	GO:0051291	protein heterooligomerization
0.35	GO:0042048	olfactory behavior

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity
0.35	GO:0005515	protein binding

0.58	GO:0032590	dendrite membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P81918|OR43B_DROME
Odorant receptor 43b
Search

0.45	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction
0.53	GO:0042048	olfactory behavior

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.55	GO:0005886	plasma membrane
0.44	GO:0030425	dendrite
0.44	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81921|OR47A_DROME
Odorant receptor 47a
Search

OR47A

0.50	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.52	GO:0005886	plasma membrane
0.40	GO:0030425	dendrite
0.40	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81922|OR47B_DROME
Odorant receptor 47b
Search

0.46	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.55	GO:0005886	plasma membrane
0.45	GO:0030425	dendrite
0.45	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81923|OR59A_DROME
Odorant receptor 59a
Search

0.45	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.54	GO:0005886	plasma membrane
0.42	GO:0030425	dendrite
0.42	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P81928|140U_DROME
RPII140-upstream gene protein
Search

0.37	Putative complex i assembly factor timmdc1 mitochondrial (Fragment)

0.51	GO:0007275	multicellular organism development
0.35	GO:0097659	nucleic acid-templated transcription
0.34	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.37	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.36	GO:0001882	nucleoside binding
0.35	GO:0003677	DNA binding

0.30

GO:0031224

intrinsic component of membrane

0.37

GO:0003899

sp|P82147|L2EFL_DROME
Protein lethal(2)essential for life
Search

0.43	Crystallin alpha B

0.65	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation
0.64	GO:0045214	sarcomere organization
0.59	GO:0042026	protein refolding
0.58	GO:0009408	response to heat
0.39	GO:0061077	chaperone-mediated protein folding
0.38	GO:0007275	multicellular organism development
0.34	GO:0007165	signal transduction

0.73	GO:0005212	structural constituent of eye lens
0.38	GO:0051082	unfolded protein binding
0.37	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.35	GO:0046872	metal ion binding

0.63	GO:0030018	Z disc
0.60	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

0.37

EC:3.1.4.17

GO:0004114

sp|P82295|PROML_DROME
Prominin-like protein
Search

0.34	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0044425	membrane part

sp|P82384|LCP9_DROME
Larval cuticle protein 9
Search

0.96	Larval cuticle protein 9

0.41	GO:0040003	chitin-based cuticle development
0.40	GO:0002168	instar larval development
0.39	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.38	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|P82701|IM18_DROME
Immune-induced peptide 18
Search

0.93	Immune-induced peptide 18

0.77	GO:0009617	response to bacterium
0.75	GO:0098542	defense response to other organism
0.52	GO:0045087	innate immune response

0.66

GO:0005576

extracellular region

sp|P82705|IM04_DROME
Immune-induced peptide 4
Search

IM4

0.97	Immune-induced molecule 4

0.82	GO:0006959	humoral immune response
0.77	GO:0009617	response to bacterium
0.75	GO:0000902	cell morphogenesis
0.72	GO:0006952	defense response

0.73

GO:0005615

extracellular space

sp|P82706|IM01_DROME
Immune-induced peptide 1
Search

0.72	GO:0009617	response to bacterium
0.68	GO:0006952	defense response
0.63	GO:0019730	antimicrobial humoral response
0.42	GO:0008063	Toll signaling pathway

0.63	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P82711|C6A19_DROME
Probable cytochrome P450 6a19
Search

0.37	Cytochrome P450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.41	GO:0048252	lauric acid metabolic process
0.41	GO:0017143	insecticide metabolic process
0.40	GO:0031000	response to caffeine
0.40	GO:0040040	thermosensory behavior
0.36	GO:0002118	aggressive behavior
0.35	GO:0050829	defense response to Gram-negative bacterium
0.33	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0009055	electron transfer activity

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P82712|CCD1P_DROME
Probable cytochrome P450 12d1 proximal, mitochondrial
Search

0.95	Probable cytochrome P450 12d1 proximal, mitochondrial

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0017085	response to insecticide
0.37	GO:0014070	response to organic cyclic compound
0.36	GO:0042493	response to drug
0.32	GO:1904668	positive regulation of ubiquitin protein ligase activity

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.37	GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0097027	ubiquitin-protein transferase activator activity
0.32	GO:0010997	anaphase-promoting complex binding

0.36	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P82713|CP392_DROME
Probable cytochrome P450 309a2
Search

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0044550	secondary metabolite biosynthetic process
0.33	GO:0040009	regulation of growth rate
0.33	GO:0046622	positive regulation of organ growth
0.33	GO:0048437	floral organ development
0.33	GO:0035265	organ growth
0.32	GO:0008284	positive regulation of cell proliferation
0.32	GO:0046222	aflatoxin metabolic process
0.32	GO:1901378	organic heteropentacyclic compound biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0030976	thiamine pyrophosphate binding
0.32	GO:0000287	magnesium ion binding

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P82804|PYM_DROME
Partner of Y14 and mago
Search

0.84	Within bgcn

0.86	GO:1903259	exon-exon junction complex disassembly
0.62	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.50	GO:0002191	cap-dependent translational initiation

0.86	GO:1990448	exon-exon junction complex binding
0.57	GO:0003723	RNA binding
0.51	GO:0031370	eukaryotic initiation factor 4G binding
0.50	GO:0008190	eukaryotic initiation factor 4E binding
0.50	GO:0043024	ribosomal small subunit binding

0.85	GO:0035145	exon-exon junction complex
0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P82890|PPAC1_DROME
Low molecular weight phosphotyrosine protein phosphatase 1
Search

0.38	Low molecular weight phosphotyrosine protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.36	GO:0098628	peptidyl-N-phospho-arginine dephosphorylation
0.34	GO:0048793	pronephros development
0.34	GO:0006265	DNA topological change
0.33	GO:0007268	chemical synaptic transmission
0.31	GO:0016310	phosphorylation

0.74	GO:0004725	protein tyrosine phosphatase activity
0.67	GO:0003993	acid phosphatase activity
0.39	GO:0004045	aminoacyl-tRNA hydrolase activity
0.36	GO:0098627	protein arginine phosphatase activity
0.34	GO:0003917	DNA topoisomerase type I activity
0.33	GO:0017124	SH3 domain binding
0.32	GO:0003676	nucleic acid binding
0.31	GO:0016301	kinase activity

0.44	GO:0005737	cytoplasm
0.41	GO:0042383	sarcolemma
0.40	GO:0009898	cytoplasmic side of plasma membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome
0.33	GO:0005634	nucleus
0.33	GO:0043005	neuron projection
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0004725

sp|P82891|PPAC2_DROME
Low molecular weight phosphotyrosine protein phosphatase 2
Search

ACP1

0.39	Low molecular weight phosphotyrosine protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0048793	pronephros development
0.34	GO:0007268	chemical synaptic transmission

0.80	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity
0.73	GO:0003993	acid phosphatase activity
0.34	GO:0003963	RNA-3'-phosphate cyclase activity
0.34	GO:0017124	SH3 domain binding

0.46	GO:0005737	cytoplasm
0.46	GO:0042383	sarcolemma
0.44	GO:0009898	cytoplasmic side of plasma membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0043005	neuron projection
0.33	GO:0005634	nucleus

0.73

EC:3.1.3.2

GO:0003993

sp|P82910|HSP70_DROME
Major heat shock 70 kDa protein Aa
Search

0.58	Major heat shock 70 kDa protein Bbb

0.43	GO:0008340	determination of adult lifespan
0.43	GO:0035080	heat shock-mediated polytene chromosome puffing
0.42	GO:0042594	response to starvation
0.40	GO:0001666	response to hypoxia
0.39	GO:0006986	response to unfolded protein
0.34	GO:0010918	positive regulation of mitochondrial membrane potential
0.34	GO:0070584	mitochondrion morphogenesis
0.34	GO:0000422	autophagy of mitochondrion
0.33	GO:0009636	response to toxic substance
0.33	GO:0006457	protein folding

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0051082	unfolded protein binding
0.33	GO:0043565	sequence-specific DNA binding

0.33

GO:0005739

mitochondrion

0.34

GO:0032440

sp|P82982|OR65A_DROME
Odorant receptor 65a
Search

0.54	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.53	GO:0005886	plasma membrane
0.40	GO:0030425	dendrite
0.40	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P82983|OR65B_DROME
Putative odorant receptor 65b
Search

0.54	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.60	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.53	GO:0005886	plasma membrane
0.41	GO:0030425	dendrite
0.41	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P82984|OR65C_DROME
Putative odorant receptor 65c
Search

0.54	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.52	GO:0005886	plasma membrane
0.41	GO:0030425	dendrite
0.41	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

sp|P82985|OR69B_DROME
Putative odorant receptor 69a, isoform B
Search

0.42	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.46	GO:0032590	dendrite membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P82986|OR82A_DROME
Odorant receptor 82a
Search

0.45	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction
0.40	GO:0032504	multicellular organism reproduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.49	GO:0005886	plasma membrane
0.41	GO:0030425	dendrite
0.41	GO:0031252	cell leading edge
0.39	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|P83088|FUCTC_DROME
Alpha-(1,3)-fucosyltransferase C
Search

FUCTC

0.36	Glycosyl transferase

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.33	GO:0016051	carbohydrate biosynthetic process

0.81	GO:0008417	fucosyltransferase activity
0.36	GO:0140103	catalytic activity, acting on a glycoprotein

0.81	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

sp|P83094|STIM_DROME
Stromal interaction molecule homolog
Search

0.55	Stromal interaction molecule

0.66	GO:0065009	regulation of molecular function
0.46	GO:0002115	store-operated calcium entry
0.45	GO:0005513	detection of calcium ion
0.45	GO:1904427	positive regulation of calcium ion transmembrane transport
0.44	GO:0022416	chaeta development
0.44	GO:0007476	imaginal disc-derived wing morphogenesis
0.44	GO:0051209	release of sequestered calcium ion into cytosol
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.85	GO:0005246	calcium channel regulator activity
0.46	GO:0048763	calcium-induced calcium release activity
0.45	GO:0015279	store-operated calcium channel activity
0.41	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding

0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P83097|WSCK_DROME
Putative tyrosine-protein kinase Wsck
Search

WSCK

0.46	Putative tyrosine-protein kinase Wsck

0.63	GO:0006468	protein phosphorylation
0.41	GO:0045087	innate immune response
0.41	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.40	GO:0042127	regulation of cell proliferation
0.39	GO:0030154	cell differentiation
0.38	GO:0018212	peptidyl-tyrosine modification
0.33	GO:0007346	regulation of mitotic cell cycle
0.32	GO:0031098	stress-activated protein kinase signaling cascade
0.32	GO:0032147	activation of protein kinase activity
0.32	GO:0035335	peptidyl-tyrosine dephosphorylation

0.63	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005102	receptor binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0004725	protein tyrosine phosphatase activity

0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0005856	cytoskeleton
0.31	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.32

GO:0004725

sp|P83098|STLK_DROME
Putative serine/threonine-protein kinase STE20-like
Search

STLK

0.97	LOW QUALITY PROTEIN: putative serine/threonine-protein kinase STE20-like

0.63	GO:0006468	protein phosphorylation
0.45	GO:0031098	stress-activated protein kinase signaling cascade
0.43	GO:0032147	activation of protein kinase activity
0.43	GO:0042981	regulation of apoptotic process
0.42	GO:0006611	protein export from nucleus
0.42	GO:0007346	regulation of mitotic cell cycle
0.40	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.36	GO:1901099	negative regulation of signal transduction in absence of ligand
0.35	GO:0043405	regulation of MAP kinase activity
0.35	GO:0043410	positive regulation of MAPK cascade

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0030295	protein kinase activator activity
0.38	GO:0019900	kinase binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0004383	guanylate cyclase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor

0.40	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.37	GO:0043233	organelle lumen
0.36	GO:0016235	aggresome
0.35	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:4.6.1.2

GO:0004383

sp|P83099|KPC4_DROME
Putative protein kinase C delta type homolog
Search

0.60	Putative protein kinase C delta type homolog

0.63	GO:0006468	protein phosphorylation
0.53	GO:0035556	intracellular signal transduction
0.41	GO:0018209	peptidyl-serine modification
0.36	GO:0006915	apoptotic process
0.35	GO:2000570	positive regulation of T-helper 2 cell activation
0.35	GO:2000318	positive regulation of T-helper 17 type immune response
0.35	GO:0007049	cell cycle
0.35	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.35	GO:0032740	positive regulation of interleukin-17 production
0.35	GO:1904355	positive regulation of telomere capping

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0046872	metal ion binding

0.41	GO:0005622	intracellular
0.35	GO:0005886	plasma membrane
0.34	GO:0043226	organelle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|P83100|MK14C_DROME
Putative mitogen-activated protein kinase 14C
Search

0.55	Mitogen-activated protein kinase

0.77	GO:0000165	MAPK cascade
0.57	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.53	GO:1902882	regulation of response to oxidative stress
0.52	GO:0038001	paracrine signaling
0.52	GO:0009617	response to bacterium
0.52	GO:0071243	cellular response to arsenic-containing substance
0.51	GO:0050832	defense response to fungus
0.51	GO:0045793	positive regulation of cell size
0.51	GO:0006970	response to osmotic stress
0.51	GO:0071276	cellular response to cadmium ion

0.79	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004386	helicase activity
0.35	GO:0003723	RNA binding
0.35	GO:0005516	calmodulin binding
0.34	GO:0003682	chromatin binding
0.34	GO:0017137	Rab GTPase binding

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.38	GO:0031970	organelle envelope lumen
0.36	GO:0019866	organelle inner membrane
0.34	GO:0098793	presynapse
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

0.79	EC:2.7.11.24	GO:0004707
0.79	KEGG:R00162	GO:0004707

sp|P83101|GSK3H_DROME
Putative glycogen synthase kinase-3 homolog
Search

0.44	Glycogen synthase kinase

0.63	GO:0006468	protein phosphorylation
0.45	GO:0048232	male gamete generation
0.37	GO:0051984	positive regulation of chromosome segregation
0.36	GO:0033047	regulation of mitotic sister chromatid segregation
0.36	GO:1905342	positive regulation of protein localization to kinetochore
0.35	GO:0090163	establishment of epithelial cell planar polarity
0.35	GO:0030589	pseudocleavage involved in syncytial blastoderm formation
0.35	GO:0035309	wing and notum subfield formation
0.35	GO:0035293	chitin-based larval cuticle pattern formation
0.35	GO:0046959	habituation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.33	GO:0008320	protein transmembrane transporter activity
0.33	GO:0005515	protein binding

0.35	GO:0035324	female germline ring canal
0.35	GO:0045169	fusome
0.34	GO:0031594	neuromuscular junction
0.34	GO:0072686	mitotic spindle
0.34	GO:0030424	axon
0.34	GO:0005813	centrosome
0.34	GO:0005938	cell cortex
0.34	GO:0030054	cell junction
0.34	GO:0005741	mitochondrial outer membrane
0.33	GO:0005654	nucleoplasm

sp|P83102|DYRK3_DROME
Putative dual specificity tyrosine-phosphorylation-regulated kinase 3 homolog
Search

0.65	Dual specificity tyrosine-phosphorylation-regulated kinase 2

0.63	GO:0006468	protein phosphorylation
0.38	GO:0018212	peptidyl-tyrosine modification
0.37	GO:0051534	negative regulation of NFAT protein import into nucleus
0.36	GO:0045725	positive regulation of glycogen biosynthetic process
0.36	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.36	GO:0007224	smoothened signaling pathway
0.35	GO:1903864	P granule disassembly
0.35	GO:0045167	asymmetric protein localization involved in cell fate determination
0.34	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.34	GO:0018210	peptidyl-threonine modification

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0030145	manganese ion binding
0.34	GO:0000287	magnesium ion binding

0.35	GO:0000151	ubiquitin ligase complex
0.34	GO:0005654	nucleoplasm
0.34	GO:0043186	P granule
0.34	GO:0005829	cytosol
0.34	GO:0072686	mitotic spindle
0.34	GO:0005813	centrosome
0.34	GO:0000793	condensed chromosome
0.34	GO:0005938	cell cortex
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|P83103|HASP_DROME
Putative serine/threonine-protein kinase haspin homolog
Search

0.64	Serine/threonine-protein kinase haspin

0.60	GO:0006468	protein phosphorylation
0.52	GO:0072356	chromosome passenger complex localization to kinetochore
0.50	GO:0018210	peptidyl-threonine modification
0.47	GO:0007064	mitotic sister chromatid cohesion
0.46	GO:0016570	histone modification
0.43	GO:0035556	intracellular signal transduction
0.36	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.35	GO:0006413	translational initiation
0.32	GO:0018212	peptidyl-tyrosine modification
0.32	GO:0006351	transcription, DNA-templated

0.60	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0001965	G-protein alpha-subunit binding
0.33	GO:0003677	DNA binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0008270	zinc ion binding

0.46	GO:0005813	centrosome
0.46	GO:0005819	spindle
0.42	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.35	GO:0005694	chromosome

sp|P83104|M3K7L_DROME
Putative mitogen-activated protein kinase kinase kinase 7-like
Search

0.86	Putative mitogen-activated protein kinase kinase kinase 7-like

0.63	GO:0006468	protein phosphorylation
0.49	GO:0035556	intracellular signal transduction
0.39	GO:0048584	positive regulation of response to stimulus
0.38	GO:0048232	male gamete generation
0.38	GO:0043405	regulation of MAP kinase activity
0.38	GO:0032147	activation of protein kinase activity
0.38	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.37	GO:0023056	positive regulation of signaling
0.37	GO:0010647	positive regulation of cell communication
0.37	GO:0018212	peptidyl-tyrosine modification

0.64	GO:0004672	protein kinase activity
0.57	GO:0005057	signal transducer activity, downstream of receptor
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.35	GO:0004383	guanylate cyclase activity
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.39	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0012505	endomembrane system
0.33	GO:1902554	serine/threonine protein kinase complex
0.33	GO:0044422	organelle part
0.33	GO:0043228	non-membrane-bounded organelle
0.32	GO:0099512	supramolecular fiber
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043234	protein complex
0.32	GO:0071944	cell periphery

0.35	EC:4.6.1.2	GO:0004383
0.32	KEGG:R00104	GO:0003951

sp|P83118|MTH11_DROME
Probable G-protein coupled receptor Mth-like 11
Search

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0006950	response to stress
0.46	GO:0008340	determination of adult lifespan
0.44	GO:0031667	response to nutrient levels
0.36	GO:0016079	synaptic vesicle exocytosis
0.35	GO:0042221	response to chemical
0.35	GO:0009266	response to temperature stimulus
0.35	GO:0007608	sensory perception of smell
0.35	GO:0050906	detection of stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.35	GO:0042277	peptide binding
0.35	GO:0001653	peptide receptor activity
0.35	GO:0005549	odorant binding
0.35	GO:0004984	olfactory receptor activity
0.34	GO:0005515	protein binding

0.39	GO:0005886	plasma membrane
0.35	GO:0098793	presynapse
0.30	GO:0016021	integral component of membrane

sp|P83119|MTH12_DROME
Probable G-protein coupled receptor Mth-like 12
Search

0.95	Probable G-protein coupled receptor Mth-like 7

0.71	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0006950	response to stress
0.53	GO:0008340	determination of adult lifespan
0.50	GO:0031667	response to nutrient levels

0.71

GO:0004930

G-protein coupled receptor activity

0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|P83262|P83262_DROME
Brother of bearded A
Search

0.92	Brother of Bearded protein A

0.87	GO:0016360	sensory organ precursor cell fate determination
0.84	GO:0001708	cell fate specification
0.82	GO:0007219	Notch signaling pathway
0.78	GO:0042742	defense response to bacterium

0.63

GO:0005515

protein binding

sp|P83293|GR64A_DROME
Gustatory receptor for sugar taste 64a
Search

0.45	Gustatory receptor

0.85	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.67	GO:0050916	sensory perception of sweet taste
0.64	GO:0034289	detection of maltose stimulus
0.63	GO:0009731	detection of sucrose stimulus
0.63	GO:0007637	proboscis extension reflex
0.61	GO:0051594	detection of glucose
0.61	GO:0007165	signal transduction
0.36	GO:0010353	response to trehalose

0.85

GO:0008527

taste receptor activity

0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P83294|GR64B_DROME
Gustatory receptor for sugar taste 64b
Search

0.46	Gustatory receptor

0.85	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.75	GO:0050916	sensory perception of sweet taste
0.61	GO:0007165	signal transduction

0.85

GO:0008527

taste receptor activity

0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P83295|GR64C_DROME
Gustatory receptor for sugar taste 64c
Search

0.54	Gustatory receptor

0.85	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.75	GO:0050916	sensory perception of sweet taste
0.61	GO:0007165	signal transduction
0.36	GO:0007637	proboscis extension reflex
0.36	GO:0010353	response to trehalose

0.85

GO:0008527

taste receptor activity

0.37	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P83296|GR64E_DROME
Gustatory receptor for sugar taste 64e
Search

0.53	Gustatory receptor

0.85	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.61	GO:0007165	signal transduction
0.59	GO:0050916	sensory perception of sweet taste
0.49	GO:0034289	detection of maltose stimulus
0.49	GO:0007637	proboscis extension reflex
0.49	GO:0009731	detection of sucrose stimulus
0.48	GO:0051594	detection of glucose
0.36	GO:0010353	response to trehalose

0.85

GO:0008527

taste receptor activity

0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P83297|GR64F_DROME
Gustatory receptor for sugar taste 64f
Search

0.56	Gustatory receptor

0.85	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.67	GO:0050916	sensory perception of sweet taste
0.61	GO:0007165	signal transduction
0.51	GO:0007637	proboscis extension reflex
0.49	GO:0034285	response to disaccharide
0.45	GO:0051594	detection of glucose

0.85

GO:0008527

taste receptor activity

0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P83474|Y818_DROME
Uncharacterized protein CG42266
Search

0.36	GO:0030198	extracellular matrix organization
0.35	GO:0007275	multicellular organism development
0.35	GO:0001886	endothelial cell morphogenesis
0.35	GO:2000353	positive regulation of endothelial cell apoptotic process
0.35	GO:0007155	cell adhesion
0.34	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.34	GO:0010171	body morphogenesis
0.34	GO:0030335	positive regulation of cell migration
0.34	GO:0008284	positive regulation of cell proliferation
0.34	GO:0048646	anatomical structure formation involved in morphogenesis

0.70	GO:0005201	extracellular matrix structural constituent
0.41	GO:0042302	structural constituent of cuticle

0.72	GO:0005581	collagen trimer
0.66	GO:0005604	basement membrane
0.35	GO:0060108	annular furrow extracellular matrix
0.35	GO:0098645	collagen network
0.34	GO:0005938	cell cortex
0.34	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P83548|VNNL3_DROME
Vanin-like protein 3
Search

0.40	Carbon-nitrogen hydrolase

0.45	GO:0006807	nitrogen compound metabolic process
0.40	GO:0009408	response to heat
0.40	GO:0016569	covalent chromatin modification
0.34	GO:0044260	cellular macromolecule metabolic process
0.34	GO:0006629	lipid metabolic process
0.34	GO:0035556	intracellular signal transduction
0.32	GO:0022900	electron transport chain

0.62	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.36	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0008121	ubiquinol-cytochrome-c reductase activity
0.32	GO:0008270	zinc ion binding

0.34	GO:0019898	extrinsic component of membrane
0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.62	EC:3.5.1	GO:0016811
0.36	KEGG:R03435	GO:0004435

sp|P83740|SC5A6_DROME
Putative sodium-dependent multivitamin transporter
Search

0.43	Multivitamin transporter

0.55	GO:0055085	transmembrane transport
0.37	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.37	GO:0051028	mRNA transport
0.37	GO:0006405	RNA export from nucleus
0.35	GO:0006814	sodium ion transport
0.34	GO:0010467	gene expression
0.33	GO:0042891	antibiotic transport

0.57	GO:0022857	transmembrane transporter activity
0.34	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P83869|IM14_DROME
Immune-induced peptide 14
Search

0.93	Immune-induced peptide 14

0.77	GO:0009617	response to bacterium
0.72	GO:0006952	defense response
0.61	GO:0006955	immune response

0.66

GO:0005576

extracellular region

sp|P83949|UBX_DROME
Homeotic protein ultrabithorax
Search

UBX

0.92	Homeotic protein ultrabithorax

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0007275	multicellular organism development
0.42	GO:0042694	muscle cell fate specification
0.41	GO:0045570	regulation of imaginal disc growth
0.41	GO:0007525	somatic muscle development
0.41	GO:0042659	regulation of cell fate specification
0.41	GO:0048636	positive regulation of muscle organ development
0.40	GO:0048332	mesoderm morphogenesis

0.63	GO:0043565	sequence-specific DNA binding
0.50	GO:0003700	DNA binding transcription factor activity
0.41	GO:0001221	transcription cofactor binding
0.40	GO:0035326	enhancer binding
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0019904	protein domain specific binding
0.38	GO:0003690	double-stranded DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.40	GO:0017053	transcriptional repressor complex
0.38	GO:0005667	transcription factor complex
0.38	GO:0032993	protein-DNA complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0004000

sp|P83967|ACT6_DROME
Actin, indirect flight muscle
Search

0.51	Actin, indirect flight muscle

0.47	GO:0071689	muscle thin filament assembly
0.46	GO:0014866	skeletal myofibril assembly
0.42	GO:0043486	histone exchange
0.41	GO:0016573	histone acetylation

0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0005515	protein binding

0.41	GO:0035267	NuA4 histone acetyltransferase complex
0.37	GO:0005856	cytoskeleton
0.34	GO:0099512	supramolecular fiber
0.33	GO:0005737	cytoplasm

sp|P83971|LYSA_DROME
Lysozyme A/C
Search

0.53	Lysozyme D

0.43	GO:0050830	defense response to Gram-positive bacterium
0.43	GO:0050829	defense response to Gram-negative bacterium
0.41	GO:0016998	cell wall macromolecule catabolic process
0.41	GO:0019835	cytolysis
0.34	GO:0045824	negative regulation of innate immune response

0.77	GO:0003796	lysozyme activity
0.35	GO:0004568	chitinase activity

0.40	GO:0005615	extracellular space
0.33	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0003796

sp|P83972|LYSD_DROME
Lysozyme D
Search

0.54	Lysozyme D

0.43	GO:0050830	defense response to Gram-positive bacterium
0.42	GO:0050829	defense response to Gram-negative bacterium
0.41	GO:0019835	cytolysis
0.41	GO:0016998	cell wall macromolecule catabolic process
0.34	GO:0045824	negative regulation of innate immune response

0.77	GO:0003796	lysozyme activity
0.35	GO:0004568	chitinase activity

0.40	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0003796

sp|P84029|CYC2_DROME
Cytochrome c-2
Search

0.40	Mitochondrial cytochrome c

0.61	GO:0022900	electron transport chain
0.40	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.37	GO:0006886	intracellular protein transport
0.37	GO:0006119	oxidative phosphorylation
0.37	GO:0016192	vesicle-mediated transport
0.36	GO:0098657	import into cell
0.36	GO:0009060	aerobic respiration
0.34	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.34	GO:0006915	apoptotic process
0.34	GO:0042743	hydrogen peroxide metabolic process

0.63	GO:0020037	heme binding
0.62	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding
0.39	GO:0035615	clathrin adaptor activity
0.36	GO:0008565	protein transporter activity

0.62	GO:0070469	respiratory chain
0.60	GO:0005739	mitochondrion
0.46	GO:0031970	organelle envelope lumen
0.40	GO:0005829	cytosol
0.38	GO:0005905	clathrin-coated pit
0.38	GO:0030117	membrane coat
0.33	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P84040|H4_DROME
Histone H4
Search

sp|P84051|H2A_DROME
Histone H2A
Search

0.43	GO:0007526	larval somatic muscle development
0.37	GO:0006342	chromatin silencing
0.35	GO:0006334	nucleosome assembly
0.32	GO:0055114	oxidation-reduction process

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0004497	monooxygenase activity
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.43	GO:0005704	polytene chromosome band
0.35	GO:0031974	membrane-enclosed lumen

0.33

GO:0016705

sp|P84180|GR22B_DROME
Putative gustatory receptor 22b
Search

0.51	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.60	GO:0007165	signal transduction
0.56	GO:0010037	response to carbon dioxide
0.55	GO:0008049	male courtship behavior
0.54	GO:0007635	chemosensory behavior
0.50	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.63	GO:0004871	signal transducer activity
0.47	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.52	GO:0043025	neuronal cell body
0.52	GO:0030425	dendrite
0.51	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P84181|GR22D_DROME
Putative gustatory receptor 22d
Search

0.53	Gustatory receptor

0.82	GO:0050909	sensory perception of taste
0.59	GO:0007165	signal transduction
0.52	GO:0010037	response to carbon dioxide
0.51	GO:0008049	male courtship behavior
0.50	GO:0007635	chemosensory behavior
0.47	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.63	GO:0004871	signal transducer activity
0.45	GO:0099600	transmembrane receptor activity

0.55	GO:0005886	plasma membrane
0.49	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.48	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

sp|P84249|H33_DROME
Histone H3.3
Search

0.43	GO:0006334	nucleosome assembly
0.37	GO:0007140	male meiotic nuclear division
0.36	GO:0034724	DNA replication-independent nucleosome organization
0.36	GO:0030307	positive regulation of cell growth

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.39	GO:0098770	FBXO family protein binding
0.35	GO:0001067	regulatory region nucleic acid binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0005700	polytene chromosome
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex

sp|P84345|ATP8_DROME
ATP synthase protein 8
Search

ATP8

0.48	ATP synthase protein 8

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016787	hydrolase activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.34

GO:0016787

sp|P91615|ADHR_DROME
Alcohol dehydrogenase-related 31 kDa protein
Search

ADHR

0.96	Alcohol dehydrogenase related

0.53	GO:0055114	oxidation-reduction process
0.39	GO:0006633	fatty acid biosynthetic process
0.34	GO:1901441	poly(hydroxyalkanoate) biosynthetic process
0.34	GO:0042618	poly-hydroxybutyrate metabolic process

0.74	GO:0004022	alcohol dehydrogenase (NAD) activity
0.43	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.40	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.40	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.40	GO:0051287	NAD binding
0.34	GO:0003858	3-hydroxybutyrate dehydrogenase activity
0.34	GO:0018454	acetoacetyl-CoA reductase activity

0.32

GO:0005737

cytoplasm

0.74	EC:1.1.1.1	GO:0004022
0.34	KEGG:R01361	GO:0003858

sp|P91621|SIF1_DROME
Protein still life, isoform SIF type 1
Search

SIF

0.84	T-lymphoma invasion and metastasis-inducing protein 2

0.76	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.40	GO:0051491	positive regulation of filopodium assembly
0.39	GO:0050770	regulation of axonogenesis
0.39	GO:0050803	regulation of synapse structure or activity
0.38	GO:0030036	actin cytoskeleton organization

0.77	GO:0005057	signal transducer activity, downstream of receptor
0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.40	GO:0048365	Rac GTPase binding

0.44	GO:0005622	intracellular
0.38	GO:0045202	synapse
0.38	GO:0030054	cell junction

sp|P91622|PDK_DROME
[Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial
Search

PDK

0.46	Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

0.57	GO:0016310	phosphorylation
0.47	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway
0.47	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.47	GO:0035357	peroxisome proliferator activated receptor signaling pathway
0.46	GO:0071398	cellular response to fatty acid
0.44	GO:2000377	regulation of reactive oxygen species metabolic process
0.44	GO:0010906	regulation of glucose metabolic process
0.44	GO:0018209	peptidyl-serine modification
0.36	GO:0006006	glucose metabolic process
0.35	GO:0006090	pyruvate metabolic process

0.60	GO:0016301	kinase activity
0.43	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005730	nucleolus
0.39	GO:0005739	mitochondrion

0.43

GO:0016773

sp|P91623|GATAC_DROME
GATA-binding factor C
Search

0.67	Endothelial transcription factor GATA-2

0.64	GO:0045582	positive regulation of T cell differentiation
0.57	GO:0006355	regulation of transcription, DNA-templated
0.54	GO:0030097	hemopoiesis
0.51	GO:0035898	parathyroid hormone secretion
0.51	GO:2000702	regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
0.51	GO:2000733	regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
0.51	GO:2000607	negative regulation of cell proliferation involved in mesonephros development
0.51	GO:1905277	negative regulation of epithelial tube formation
0.51	GO:2000611	positive regulation of thyroid hormone generation
0.51	GO:0061290	canonical Wnt signaling pathway involved in metanephric kidney development

0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0044212	transcription regulatory region DNA binding
0.57	GO:0003690	double-stranded DNA binding
0.50	GO:0071837	HMG box domain binding
0.50	GO:0005134	interleukin-2 receptor binding
0.48	GO:0001085	RNA polymerase II transcription factor binding
0.46	GO:0003713	transcription coactivator activity
0.46	GO:0003682	chromatin binding

0.53	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.44	GO:0000785	chromatin
0.42	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

tr|P91634|P91634_DROME
PI-3 kinase
Search

0.72	Phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta

0.81	GO:0048015	phosphatidylinositol-mediated signaling
0.80	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.53	GO:0055115	entry into diapause
0.53	GO:0045572	positive regulation of imaginal disc growth
0.53	GO:0051823	regulation of synapse structural plasticity
0.53	GO:0007436	larval salivary gland morphogenesis
0.53	GO:0030536	larval feeding behavior
0.53	GO:0035212	cell competition in a multicellular organism
0.53	GO:0060074	synapse maturation

0.81	GO:0035004	phosphatidylinositol 3-kinase activity
0.80	GO:0052742	phosphatidylinositol kinase activity
0.59	GO:0052813	phosphatidylinositol bisphosphate kinase activity
0.54	GO:0016307	phosphatidylinositol phosphate kinase activity
0.51	GO:0001727	lipid kinase activity
0.49	GO:0017124	SH3 domain binding
0.46	GO:0043560	insulin receptor substrate binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding

0.54	GO:0005942	phosphatidylinositol 3-kinase complex
0.46	GO:0030496	midbody
0.45	GO:0005622	intracellular
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0043228	non-membrane-bounded organelle
0.38	GO:0044422	organelle part
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0005886	plasma membrane
0.34	GO:0005903	brush border
0.33	GO:0120038	plasma membrane bounded cell projection part

0.81

GO:0035004

sp|P91641|MED20_DROME
Mediator of RNA polymerase II transcription subunit 20
Search

MED20

0.97	Mediator of RNA polymerase II transcription subunit 20

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.36	GO:0006629	lipid metabolic process
0.34	GO:0055114	oxidation-reduction process

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.39	GO:0003713	transcription coactivator activity
0.37	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.35	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.77	GO:0016592	mediator complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:1.3

GO:0016627

sp|P91645|CAC1A_DROME
Voltage-dependent calcium channel type A subunit alpha-1
Search

0.59	Voltage-dependent L-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.37	GO:0086010	membrane depolarization during action potential
0.36	GO:0016057	regulation of membrane potential in photoreceptor cell
0.36	GO:0045433	male courtship behavior, veined wing generated song production
0.36	GO:0042045	epithelial fluid transport
0.36	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.36	GO:0070050	neuron cellular homeostasis
0.36	GO:0050908	detection of light stimulus involved in visual perception
0.36	GO:0016322	neuron remodeling

0.82	GO:0005245	voltage-gated calcium channel activity
0.68	GO:0005509	calcium ion binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.35	GO:0031594	neuromuscular junction
0.35	GO:0048786	presynaptic active zone
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0016324	apical plasma membrane
0.32	GO:0005622	intracellular

sp|P91657|OPS5_DROME
Opsin Rh5
Search

0.60	Blue-sensitive visual pigment

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.71	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0043052	thermotaxis
0.48	GO:0016038	absorption of visible light
0.48	GO:0043153	entrainment of circadian clock by photoperiod
0.46	GO:0009584	detection of visible light
0.46	GO:0007605	sensory perception of sound
0.34	GO:0051938	L-glutamate import

0.76	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005314	high-affinity glutamate transmembrane transporter activity
0.34	GO:0015321	sodium-dependent phosphate transmembrane transporter activity

0.48	GO:0016028	rhabdomere
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|P91659|P91659_DROME
CG2187, isoform A
Search

0.40	Sodium-dependent multivitamin transporter

0.55	GO:0055085	transmembrane transport
0.32	GO:0016310	phosphorylation

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0046872	metal ion binding
0.32	GO:0016301	kinase activity

0.47	GO:0016323	basolateral plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P91660|L259_DROME
Probable multidrug resistance-associated protein lethal(2)03659
Search

0.67	Multidrug resistance protein 4

0.55	GO:0055085	transmembrane transport
0.48	GO:0034059	response to anoxia
0.48	GO:0007275	multicellular organism development
0.46	GO:0001666	response to hypoxia
0.45	GO:0007568	aging
0.44	GO:0060429	epithelium development
0.43	GO:0015711	organic anion transport
0.42	GO:0006979	response to oxidative stress
0.34	GO:0042060	wound healing

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0015562	efflux transmembrane transporter activity
0.44	GO:0008514	organic anion transmembrane transporter activity

0.40

GO:0005887

integral component of plasma membrane

sp|P91664|MAX_DROME
Protein max
Search

0.73	Transcription factor Max

0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0006351	transcription, DNA-templated

0.68	GO:0046983	protein dimerization activity
0.49	GO:0003700	DNA binding transcription factor activity
0.35	GO:0070888	E-box binding
0.34	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.77	GO:0090575	RNA polymerase II transcription factor complex
0.34	GO:0000790	nuclear chromatin
0.34	GO:0032993	protein-DNA complex
0.30	GO:0031224	intrinsic component of membrane

sp|P91679|PEPT1_DROME
Peptide transporter family 1
Search

0.54	Proton-dependent oligopeptide transporter

0.78	GO:0006857	oligopeptide transport
0.55	GO:0055085	transmembrane transport
0.34	GO:0015031	protein transport

0.57	GO:0022857	transmembrane transporter activity
0.43	GO:0015197	peptide transporter activity

0.37	GO:0030670	phagocytic vesicle membrane
0.35	GO:0005887	integral component of plasma membrane

sp|P91682|SMO_DROME
Protein smoothened
Search

0.87	Smoothened receptor

0.83	GO:0007224	smoothened signaling pathway
0.68	GO:0007275	multicellular organism development
0.55	GO:0002066	columnar/cuboidal epithelial cell development
0.54	GO:0002009	morphogenesis of an epithelium
0.53	GO:0009967	positive regulation of signal transduction
0.51	GO:0002385	mucosal immune response
0.51	GO:1903829	positive regulation of cellular protein localization
0.51	GO:0035019	somatic stem cell population maintenance
0.51	GO:0045746	negative regulation of Notch signaling pathway
0.51	GO:0042981	regulation of apoptotic process

0.70	GO:0004888	transmembrane signaling receptor activity
0.52	GO:0005113	patched binding
0.46	GO:0042802	identical protein binding
0.45	GO:0017147	Wnt-protein binding
0.41	GO:0008142	oxysterol binding
0.38	GO:0008144	drug binding
0.32	GO:0046872	metal ion binding

0.53	GO:0005929	cilium
0.51	GO:0120038	plasma membrane bounded cell projection part
0.49	GO:0043025	neuronal cell body
0.49	GO:0097447	dendritic tree
0.48	GO:0030424	axon
0.47	GO:0005901	caveola
0.43	GO:0005887	integral component of plasma membrane
0.43	GO:0005794	Golgi apparatus
0.42	GO:0098588	bounding membrane of organelle
0.36	GO:0031982	vesicle

sp|P91685|GRM_DROME
Metabotropic glutamate receptor
Search

0.64	Metabotropic glutamate receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0051966	regulation of synaptic transmission, glutamatergic
0.50	GO:0072553	terminal button organization
0.49	GO:0007614	short-term memory
0.49	GO:0007215	glutamate receptor signaling pathway
0.49	GO:0008049	male courtship behavior
0.49	GO:0007616	long-term memory
0.48	GO:0007528	neuromuscular junction development
0.48	GO:0007612	learning
0.42	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration

0.72	GO:0004930	G-protein coupled receptor activity
0.51	GO:0016595	glutamate binding
0.49	GO:0008066	glutamate receptor activity
0.48	GO:0015485	cholesterol binding
0.42	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.33	GO:0010855	adenylate cyclase inhibitor activity
0.33	GO:0070905	serine binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0005246	calcium channel regulator activity
0.32	GO:0005245	voltage-gated calcium channel activity

0.53	GO:0005886	plasma membrane
0.47	GO:0098857	membrane microdomain
0.41	GO:0043235	receptor complex
0.41	GO:0032279	asymmetric synapse
0.41	GO:0099572	postsynaptic specialization
0.40	GO:0097458	neuron part
0.39	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0005634	nucleus
0.33	GO:0005938	cell cortex
0.31	GO:0005791	rough endoplasmic reticulum

0.33

EC:2.3

GO:0016746

sp|P91875|RPA1_DROME
DNA-directed RNA polymerase I subunit RPA1
Search

0.47	DNA-directed RNA polymerase subunit

0.58	GO:0006351	transcription, DNA-templated
0.48	GO:1904750	negative regulation of protein localization to nucleolus
0.37	GO:0048703	embryonic viscerocranium morphogenesis
0.37	GO:0014032	neural crest cell development
0.36	GO:0007098	centrosome cycle
0.36	GO:0007051	spindle organization
0.36	GO:0006325	chromatin organization
0.35	GO:0040029	regulation of gene expression, epigenetic
0.33	GO:0016458	gene silencing
0.33	GO:0010628	positive regulation of gene expression

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.43	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.44	GO:0000428	DNA-directed RNA polymerase complex
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.36	GO:0017053	transcriptional repressor complex
0.34	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

0.70

GO:0003899

sp|P91891|MO25_DROME
Protein Mo25
Search

0.32	Calcium binding protein 39

0.84	GO:0001700	embryonic development via the syncytial blastoderm
0.41	GO:0006357	regulation of transcription by RNA polymerase II

0.43

GO:0001104

RNA polymerase II transcription cofactor activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0043234	protein complex
0.37	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P91926|AP2A_DROME
AP-2 complex subunit alpha
Search

0.71	AP-2 complex subunit alpha

0.71	GO:0072583	clathrin-dependent endocytosis
0.69	GO:0006886	intracellular protein transport
0.38	GO:0048488	synaptic vesicle endocytosis
0.36	GO:1990386	mitotic cleavage furrow ingression
0.35	GO:0008356	asymmetric cell division
0.35	GO:0045807	positive regulation of endocytosis
0.35	GO:0030707	ovarian follicle cell development
0.35	GO:0097480	establishment of synaptic vesicle localization
0.35	GO:0022900	electron transport chain

0.84	GO:0035615	clathrin adaptor activity
0.68	GO:0008565	protein transporter activity
0.35	GO:0020037	heme binding
0.35	GO:0009055	electron transfer activity
0.34	GO:0046872	metal ion binding

0.78	GO:0030131	clathrin adaptor complex
0.77	GO:0005905	clathrin-coated pit
0.37	GO:0045202	synapse
0.35	GO:0005794	Golgi apparatus
0.35	GO:0030128	clathrin coat of endocytic vesicle
0.34	GO:0005886	plasma membrane

sp|P91927|A60DA_DROME
LETM1 and EF-hand domain-containing protein anon-60Da, mitochondrial
Search

0.71	LETM1 and EF-hand domain-containing protein 1, mitochondrial

0.54	GO:0070584	mitochondrion morphogenesis
0.54	GO:0006851	mitochondrial calcium ion transmembrane transport
0.53	GO:0071456	cellular response to hypoxia
0.52	GO:0099643	signal release from synapse
0.52	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.50	GO:0035725	sodium ion transmembrane transport
0.49	GO:0006836	neurotransmitter transport
0.48	GO:0071805	potassium ion transmembrane transport
0.48	GO:0001505	regulation of neurotransmitter levels
0.46	GO:0051649	establishment of localization in cell

0.74	GO:0043022	ribosome binding
0.66	GO:0005509	calcium ion binding
0.54	GO:0005432	calcium:sodium antiporter activity
0.53	GO:0015386	potassium:proton antiporter activity
0.42	GO:0004531	deoxyribonuclease II activity

0.61	GO:0005739	mitochondrion
0.51	GO:0098793	presynapse
0.44	GO:0031967	organelle envelope
0.44	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.42

EC:3.1.22.1

GO:0004531

sp|P91928|MIC60_DROME
MICOS complex subunit Mic60
Search

0.63	MICOS complex subunit MIC60

0.61	GO:0070584	mitochondrion morphogenesis
0.38	GO:0000160	phosphorelay signal transduction system
0.30	GO:0008152	metabolic process

0.38	GO:0004871	signal transducer activity
0.34	GO:0003723	RNA binding
0.30	GO:0003824	catalytic activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.32	GO:0005761	mitochondrial ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|P91929|NDUAA_DROME
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
Search

0.66	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

0.74	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.40	GO:0032981	mitochondrial respiratory chain complex I assembly
0.34	GO:0006270	DNA replication initiation
0.33	GO:0007029	endoplasmic reticulum organization
0.33	GO:0006493	protein O-linked glycosylation
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0042493	response to drug
0.32	GO:0009165	nucleotide biosynthetic process

0.38	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.34	GO:0008408	3'-5' exonuclease activity
0.34	GO:0016301	kinase activity
0.32	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0003676	nucleic acid binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005747	mitochondrial respiratory chain complex I
0.70	GO:0005759	mitochondrial matrix
0.38	GO:0043209	myelin sheath
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:1.6.5.3

GO:0008137

sp|P91931|DCAM_DROME
S-adenosylmethionine decarboxylase proenzyme
Search

0.55	S-adenosylmethionine decarboxylase proenzyme

0.85	GO:0006597	spermine biosynthetic process
0.78	GO:0008295	spermidine biosynthetic process
0.72	GO:0006557	S-adenosylmethioninamine biosynthetic process
0.48	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0001701	in utero embryonic development
0.34	GO:0046500	S-adenosylmethionine metabolic process

0.82	GO:0004014	adenosylmethionine decarboxylase activity
0.43	GO:0019810	putrescine binding
0.33	GO:0005515	protein binding

0.40	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.82	EC:4.1.1.50	GO:0004014
0.82	KEGG:R00178	GO:0004014

sp|P91938|TRXR1_DROME
Thioredoxin reductase 1, mitochondrial
Search

0.32	Pyridine nucleotide-disulfide oxidoreductase

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.59	GO:0022900	electron transport chain
0.46	GO:0008340	determination of adult lifespan
0.45	GO:0001666	response to hypoxia
0.39	GO:0000305	response to oxygen radical
0.34	GO:0042395	ecdysis, collagen and cuticulin-based cuticle
0.34	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.78	GO:0004791	thioredoxin-disulfide reductase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.60	GO:0009055	electron transfer activity
0.45	GO:0004362	glutathione-disulfide reductase activity
0.43	GO:0042803	protein homodimerization activity
0.41	GO:0015035	protein disulfide oxidoreductase activity
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0046872	metal ion binding

0.40	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78	EC:1.8.1.9	GO:0004791
0.78	KEGG:R02016	GO:0004791

tr|P91939|P91939_DROME
Cuticle protein LCP65Ad
Search

0.84	larval cuticle protein 8

0.42	GO:0040003	chitin-based cuticle development
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.79	GO:0042302	structural constituent of cuticle
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0003676	nucleic acid binding

0.39	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.33

GO:0004523

tr|P91940|P91940_DROME
Cuticle protein LCP65Aa
Search

0.63	Endocuticle structural glycoprotein SgAbd-1

0.42

GO:0040003

chitin-based cuticle development

0.79

GO:0042302

structural constituent of cuticle

0.39	GO:0031012	extracellular matrix
0.30	GO:0044425	membrane part

tr|P91941|P91941_DROME
Adult cuticle protein 65Aa
Search

0.81	LOW QUALITY PROTEIN: endocuticle structural protein SgAbd-6

0.42	GO:0040003	chitin-based cuticle development
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.79	GO:0042302	structural constituent of cuticle
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0003676	nucleic acid binding

0.39	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.33

GO:0004523

tr|P91942|P91942_DROME
Cuticle protein LCP65Ae
Search

0.93	Larval cuticle protein 8

0.43	GO:0040003	chitin-based cuticle development
0.35	GO:0002168	instar larval development
0.35	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.40	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|P92029|DNJ60_DROME
DnaJ-like protein 60
Search

0.59	GO:0007283	spermatogenesis
0.38	GO:0030154	cell differentiation
0.38	GO:0007275	multicellular organism development
0.38	GO:0006457	protein folding
0.34	GO:0031204	posttranslational protein targeting to membrane, translocation
0.34	GO:0017182	peptidyl-diphthamide metabolic process
0.34	GO:1900247	regulation of cytoplasmic translational elongation
0.32	GO:0009058	biosynthetic process

0.38	GO:0051082	unfolded protein binding
0.35	GO:0046872	metal ion binding

0.34	GO:0010598	NAD(P)H dehydrogenase complex (plastoquinone)
0.34	GO:0031984	organelle subcompartment
0.34	GO:0009536	plastid
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0044432	endoplasmic reticulum part
0.33	GO:0042651	thylakoid membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P92177|1433E_DROME
14-3-3 protein epsilon
Search

0.79	Multifunctional chaperone

0.48	GO:1905912	regulation of calcium ion export across plasma membrane
0.47	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.47	GO:0016477	cell migration
0.46	GO:0008103	oocyte microtubule cytoskeleton polarization
0.46	GO:0048699	generation of neurons
0.46	GO:0007294	germarium-derived oocyte fate determination
0.46	GO:0009628	response to abiotic stimulus
0.46	GO:0046827	positive regulation of protein export from nucleus
0.46	GO:0060306	regulation of membrane repolarization
0.46	GO:0048190	wing disc dorsal/ventral pattern formation

0.77	GO:0019904	protein domain specific binding
0.52	GO:0050815	phosphoserine residue binding
0.47	GO:0046982	protein heterodimerization activity
0.45	GO:0015459	potassium channel regulator activity
0.45	GO:0097110	scaffold protein binding
0.45	GO:0005246	calcium channel regulator activity
0.45	GO:0044325	ion channel binding
0.45	GO:0042826	histone deacetylase binding
0.44	GO:0045296	cadherin binding
0.43	GO:0031625	ubiquitin protein ligase binding

0.46	GO:0045172	germline ring canal
0.42	GO:0005634	nucleus
0.41	GO:0090724	central region of growth cone
0.40	GO:0005694	chromosome
0.39	GO:0042470	melanosome
0.38	GO:0005871	kinesin complex
0.38	GO:0030424	axon
0.38	GO:0005739	mitochondrion
0.37	GO:0005886	plasma membrane
0.37	GO:0005829	cytosol

0.34

EC:3.5.1.98

GO:0032041

tr|P92181|P92181_DROME
Cuticle protein DCP2
Search

0.95	larval cuticle protein 8

0.41	GO:0040003	chitin-based cuticle development
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.79	GO:0042302	structural constituent of cuticle
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0003676	nucleic acid binding

0.38	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.33

GO:0004523

sp|P92189|STIL_DROME
Protein stand still
Search

0.80	Protein stand still

0.87	GO:0030237	female sex determination
0.84	GO:0046660	female sex differentiation
0.50	GO:0048477	oogenesis
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.75

GO:0000790

nuclear chromatin

sp|P92192|LCP5_DROME
Larval cuticle protein 5
Search

0.95	Larval cuticle protein 5

0.42	GO:0040003	chitin-based cuticle development
0.37	GO:0002168	instar larval development
0.37	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.41	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

tr|P92194|P92194_DROME
Cuticle protein DCP7
Search

0.91	Larval cuticle protein 8

0.42	GO:0040003	chitin-based cuticle development
0.36	GO:0002168	instar larval development
0.36	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.40	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|P92201|LCP8_DROME
Larval cuticle protein 8
Search

0.92	Larval cuticle protein 8

0.42	GO:0040003	chitin-based cuticle development
0.37	GO:0002168	instar larval development
0.37	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.39	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|P92204|NELFE_DROME
Negative elongation factor E
Search

0.89	Negative elongation factor E

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006414	translational elongation
0.52	GO:0006368	transcription elongation from RNA polymerase II promoter
0.49	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process
0.48	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0009982	pseudouridine synthase activity
0.34	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0032021	NELF complex
0.52	GO:0017053	transcriptional repressor complex
0.37	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:5.4.99.12

GO:0009982

sp|P92208|JNK_DROME
Stress-activated protein kinase JNK
Search

0.59	Stress-activated protein kinase JNK

0.79	GO:0000165	MAPK cascade
0.48	GO:1903688	positive regulation of border follicle cell migration
0.48	GO:1904801	positive regulation of neuron remodeling
0.48	GO:0048674	collateral sprouting of injured axon
0.48	GO:0048615	embryonic anterior midgut (ectodermal) morphogenesis
0.48	GO:0046844	micropyle formation
0.48	GO:0007395	dorsal closure, spreading of leading edge cells
0.47	GO:0031098	stress-activated protein kinase signaling cascade
0.47	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.47	GO:0046528	imaginal disc fusion

0.81	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.35	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.45	GO:0043005	neuron projection
0.45	GO:0005622	intracellular
0.44	GO:0036477	somatodendritic compartment
0.43	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0044297	cell body
0.35	GO:0043227	membrane-bounded organelle
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P98081|DAB_DROME
Protein disabled
Search

0.69	GO:0045500	sevenless signaling pathway
0.65	GO:0042051	compound eye photoreceptor development
0.64	GO:0007391	dorsal closure
0.64	GO:0048488	synaptic vesicle endocytosis
0.64	GO:0007349	cellularization
0.64	GO:0008045	motor neuron axon guidance
0.55	GO:0072583	clathrin-dependent endocytosis

0.67	GO:0005118	sevenless binding
0.65	GO:0042169	SH2 domain binding
0.60	GO:0017124	SH3 domain binding

0.60	GO:0030424	axon
0.57	GO:0045202	synapse
0.41	GO:0005737	cytoplasm

sp|P98149|DIF_DROME
Dorsal-related immunity factor Dif
Search

0.59	Embryonic polarity protein dorsal

0.66	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.53	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.51	GO:0071224	cellular response to peptidoglycan
0.51	GO:0071316	cellular response to nicotine
0.51	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
0.51	GO:2000630	positive regulation of miRNA metabolic process
0.51	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.51	GO:0071223	cellular response to lipoteichoic acid

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0071532	ankyrin repeat binding
0.50	GO:0051059	NF-kappaB binding
0.49	GO:0070491	repressing transcription factor binding
0.49	GO:0047485	protein N-terminus binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0033613	activating transcription factor binding
0.49	GO:0042826	histone deacetylase binding
0.48	GO:0003682	chromatin binding

0.70	GO:0071159	NF-kappaB complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.47	GO:0033256	I-kappaB/NF-kappaB complex
0.46	GO:0005667	transcription factor complex
0.44	GO:0000785	chromatin
0.43	GO:0070013	intracellular organelle lumen

sp|P98159|NUDEL_DROME
Serine protease nudel
Search

0.10	Serine protease nudel

0.84	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.81	GO:0007306	eggshell chorion assembly
0.69	GO:0007343	egg activation
0.59	GO:0016485	protein processing
0.42	GO:0006898	receptor-mediated endocytosis
0.36	GO:0034436	glycoprotein transport
0.36	GO:0034447	very-low-density lipoprotein particle clearance
0.36	GO:0038026	reelin-mediated signaling pathway
0.35	GO:1900006	positive regulation of dendrite development
0.35	GO:0021517	ventral spinal cord development

0.67	GO:0004252	serine-type endopeptidase activity
0.44	GO:0038024	cargo receptor activity
0.41	GO:0005509	calcium ion binding
0.36	GO:0038025	reelin receptor activity
0.36	GO:0034437	glycoprotein transporter activity
0.36	GO:0034189	very-low-density lipoprotein particle binding
0.36	GO:0034185	apolipoprotein binding
0.35	GO:0048306	calcium-dependent protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0016491	oxidoreductase activity

0.36	GO:0005576	extracellular region
0.35	GO:0043235	receptor complex
0.33	GO:0036338	viral membrane
0.33	GO:1990777	lipoprotein particle
0.33	GO:0005905	clathrin-coated pit
0.30	GO:0016021	integral component of membrane

0.67

GO:0004252

sp|P98163|YL_DROME
Putative vitellogenin receptor
Search

0.52	Low-density lipoprotein receptor domain class A

0.43	GO:0048477	oogenesis
0.42	GO:0006898	receptor-mediated endocytosis
0.36	GO:0051239	regulation of multicellular organismal process
0.36	GO:0007417	central nervous system development
0.36	GO:0022008	neurogenesis
0.36	GO:1904447	folic acid import across plasma membrane
0.35	GO:0003223	ventricular compact myocardium morphogenesis
0.35	GO:0060982	coronary artery morphogenesis
0.35	GO:0061156	pulmonary artery morphogenesis
0.35	GO:0003139	secondary heart field specification

0.69	GO:0005509	calcium ion binding
0.49	GO:0008196	vitellogenin receptor activity
0.35	GO:0034185	apolipoprotein binding
0.35	GO:0030228	lipoprotein particle receptor activity
0.34	GO:0016964	alpha-2 macroglobulin receptor activity
0.34	GO:0038025	reelin receptor activity
0.34	GO:0032050	clathrin heavy chain binding
0.34	GO:0008144	drug binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0003677	DNA binding

0.53	GO:0030135	coated vesicle
0.38	GO:0005886	plasma membrane
0.36	GO:0043235	receptor complex
0.36	GO:0098589	membrane region
0.35	GO:0005768	endosome
0.35	GO:0005903	brush border
0.35	GO:0030425	dendrite
0.35	GO:0030139	endocytic vesicle
0.35	GO:0030424	axon
0.35	GO:0045177	apical part of cell

sp|Q00168|KCC2A_DROME
Calcium/calmodulin-dependent protein kinase type II alpha chain
Search

LOC108095014

0.47	Calcium/calmodulin-dependent protein kinase type II subunit beta

0.63	GO:0006468	protein phosphorylation
0.37	GO:0018210	peptidyl-threonine modification
0.37	GO:0018209	peptidyl-serine modification
0.36	GO:0060278	regulation of ovulation
0.36	GO:0008049	male courtship behavior
0.36	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.36	GO:0007616	long-term memory
0.36	GO:0051489	regulation of filopodium assembly
0.36	GO:0030154	cell differentiation
0.36	GO:0007528	neuromuscular junction development

0.77	GO:0004683	calmodulin-dependent protein kinase activity
0.72	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005954	calcium- and calmodulin-dependent protein kinase complex
0.37	GO:0043005	neuron projection
0.36	GO:0048786	presynaptic active zone
0.35	GO:0036477	somatodendritic compartment
0.35	GO:0045211	postsynaptic membrane
0.35	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.77

EC:2.7.11.17

GO:0004683

sp|Q00174|LAMA_DROME
Laminin subunit alpha
Search

0.78	laminin subunit alpha

0.81	GO:0045995	regulation of embryonic development
0.77	GO:0030334	regulation of cell migration
0.74	GO:0030155	regulation of cell adhesion
0.71	GO:0007155	cell adhesion
0.50	GO:0035001	dorsal trunk growth, open tracheal system
0.49	GO:0035011	melanotic encapsulation of foreign target
0.48	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.47	GO:0007498	mesoderm development
0.46	GO:0007411	axon guidance
0.45	GO:0007507	heart development

0.71	GO:0005102	receptor binding
0.36	GO:0004714	transmembrane receptor protein tyrosine kinase activity

0.50	GO:0036062	presynaptic periactive zone
0.48	GO:0005605	basal lamina
0.34	GO:0008021	synaptic vesicle
0.34	GO:0030424	axon
0.34	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.36

EC:2.7.10.1

GO:0004714

sp|Q00449|MDR49_DROME
Multidrug resistance protein homolog 49
Search

MDR49

0.25	ATP-binding cassette transporter

0.57	GO:0097254	renal tubular secretion
0.55	GO:0055085	transmembrane transport
0.54	GO:0008354	germ cell migration
0.52	GO:0001666	response to hypoxia
0.47	GO:0009636	response to toxic substance
0.47	GO:0048058	compound eye corneal lens development
0.43	GO:0042391	regulation of membrane potential
0.40	GO:0042908	xenobiotic transport
0.38	GO:0015893	drug transport
0.38	GO:0010038	response to metal ion

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0015562	efflux transmembrane transporter activity
0.40	GO:0042910	xenobiotic transmembrane transporter activity
0.39	GO:0015238	drug transmembrane transporter activity
0.31	GO:0004601	peroxidase activity
0.31	GO:0020037	heme binding

0.41	GO:0005887	integral component of plasma membrane
0.37	GO:0016324	apical plasma membrane
0.37	GO:0043190	ATP-binding cassette (ABC) transporter complex
0.36	GO:0005919	pleated septate junction

0.31	EC:1.11.1.7	GO:0004601
0.31	KEGG:R03532	GO:0004601

sp|Q00637|SODM_DROME
Superoxide dismutase [Mn], mitochondrial
Search

0.47	Mn-superoxide dismutase

0.75	GO:0019430	removal of superoxide radicals
0.52	GO:0055114	oxidation-reduction process
0.44	GO:0051597	response to methylmercury
0.44	GO:0001780	neutrophil homeostasis
0.42	GO:0046686	response to cadmium ion
0.41	GO:0045087	innate immune response
0.36	GO:0007568	aging
0.36	GO:0007507	heart development
0.36	GO:0038001	paracrine signaling
0.36	GO:0035206	regulation of hemocyte proliferation

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0042803	protein homodimerization activity

0.38	GO:0097249	mitochondrial respiratory chain supercomplex
0.36	GO:0005759	mitochondrial matrix
0.34	GO:0043209	myelin sheath

0.77

EC:1.15.1.1

GO:0004784

sp|Q00725|SGS4_DROME
Salivary glue protein Sgs-4
Search

0.73	Salivary glue protein Sgs-4

0.58	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q00748|MDR65_DROME
Multidrug resistance protein homolog 65
Search

0.22	ABC transporter

0.68	GO:0097254	renal tubular secretion
0.55	GO:0055085	transmembrane transport
0.53	GO:0009636	response to toxic substance
0.49	GO:0060857	establishment of glial blood-brain barrier
0.48	GO:0042908	xenobiotic transport
0.46	GO:0008354	germ cell migration
0.45	GO:0015893	drug transport
0.44	GO:0001666	response to hypoxia
0.35	GO:0048058	compound eye corneal lens development
0.35	GO:1901998	toxin transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042910	xenobiotic transmembrane transporter activity
0.47	GO:0015562	efflux transmembrane transporter activity
0.45	GO:0015238	drug transmembrane transporter activity
0.35	GO:0019534	toxin transmembrane transporter activity
0.35	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity

0.50	GO:0005919	pleated septate junction
0.43	GO:0043190	ATP-binding cassette (ABC) transporter complex
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0016324	apical plasma membrane

sp|Q00805|GIL_DROME
Protein giant-lens
Search

0.88	GO:0060233	oenocyte delamination
0.86	GO:0007482	haltere development
0.86	GO:0016318	ommatidial rotation
0.86	GO:0007455	eye-antennal disc morphogenesis
0.85	GO:0035215	genital disc development
0.85	GO:0007474	imaginal disc-derived wing vein specification
0.85	GO:2000737	negative regulation of stem cell differentiation
0.81	GO:0050768	negative regulation of neurogenesis
0.78	GO:0043065	positive regulation of apoptotic process
0.52	GO:0009996	negative regulation of cell fate specification

0.73	GO:0042802	identical protein binding
0.52	GO:0048019	receptor antagonist activity
0.51	GO:0005154	epidermal growth factor receptor binding

0.43	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q00963|SPTCB_DROME
Spectrin beta chain
Search

0.77	Spectrin beta chain

0.79	GO:0051693	actin filament capping
0.70	GO:0007010	cytoskeleton organization
0.36	GO:0042062	long-term strengthening of neuromuscular junction
0.36	GO:0048790	maintenance of presynaptic active zone structure
0.36	GO:0072499	photoreceptor cell axon guidance
0.36	GO:0016199	axon midline choice point recognition
0.35	GO:0007026	negative regulation of microtubule depolymerization
0.35	GO:0007274	neuromuscular synaptic transmission
0.35	GO:0007009	plasma membrane organization

0.76	GO:0005200	structural constituent of cytoskeleton
0.73	GO:0003779	actin binding
0.67	GO:0005543	phospholipid binding
0.35	GO:0030506	ankyrin binding
0.35	GO:0005516	calmodulin binding
0.34	GO:0008017	microtubule binding
0.32	GO:0016787	hydrolase activity

0.85	GO:0008091	spectrin
0.36	GO:0045170	spectrosome
0.35	GO:0045169	fusome
0.35	GO:0016327	apicolateral plasma membrane
0.35	GO:0016328	lateral plasma membrane
0.35	GO:0031594	neuromuscular junction
0.35	GO:0030424	axon

0.32

GO:0016787

tr|Q00G30|Q00G30_DROME
Sno oncogene, isoform B
Search

SNOO

0.92	Sno oncogene, isoform B

0.84	GO:0090099	negative regulation of decapentaplegic signaling pathway
0.77	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.76	GO:0048813	dendrite morphogenesis
0.46	GO:0030514	negative regulation of BMP signaling pathway
0.45	GO:0045596	negative regulation of cell differentiation
0.36	GO:0001947	heart looping
0.36	GO:0051216	cartilage development
0.36	GO:0009953	dorsal/ventral pattern formation
0.34	GO:0060079	excitatory postsynaptic potential
0.34	GO:0035235	ionotropic glutamate receptor signaling pathway

0.77	GO:0046332	SMAD binding
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity
0.34	GO:0004970	ionotropic glutamate receptor activity
0.32	GO:0043531	ADP binding

0.56	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.34	GO:0098794	postsynapse
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q01068|ESM3_DROME
Enhancer of split m3 protein
Search

0.78	Enhancer of split region protein HLHmb

0.62	GO:1902692	regulation of neuroblast proliferation
0.60	GO:2000648	positive regulation of stem cell proliferation
0.60	GO:2000179	positive regulation of neural precursor cell proliferation
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0050769	positive regulation of neurogenesis
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0051253	negative regulation of RNA metabolic process
0.49	GO:0010558	negative regulation of macromolecule biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.57	GO:1990837	sequence-specific double-stranded DNA binding
0.44	GO:0008134	transcription factor binding
0.43	GO:0003700	DNA binding transcription factor activity
0.43	GO:0035326	enhancer binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q01069|ESMB_DROME
Enhancer of split mbeta protein
Search

0.82	Enhancer of split region protein HLHmb

0.59	GO:0002052	positive regulation of neuroblast proliferation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0051253	negative regulation of RNA metabolic process
0.49	GO:0010558	negative regulation of macromolecule biosynthetic process
0.49	GO:0031327	negative regulation of cellular biosynthetic process
0.45	GO:0048190	wing disc dorsal/ventral pattern formation
0.45	GO:0097150	neuronal stem cell population maintenance

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.44	GO:0008134	transcription factor binding
0.42	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q01070|ESMC_DROME
Enhancer of split mgamma protein
Search

0.85	Enhancer of split region protein HLHmg

0.59	GO:0002052	positive regulation of neuroblast proliferation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0048190	wing disc dorsal/ventral pattern formation
0.51	GO:0097150	neuronal stem cell population maintenance
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process
0.50	GO:0031327	negative regulation of cellular biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.48	GO:0008134	transcription factor binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q01071|ESMD_DROME
Enhancer of split mdelta protein
Search

0.92	Enhancer of split region protein HLHmd

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:1902692	regulation of neuroblast proliferation
0.53	GO:0048052	R1/R6 cell differentiation
0.51	GO:0045466	R7 cell differentiation
0.51	GO:0007525	somatic muscle development
0.45	GO:0051253	negative regulation of RNA metabolic process
0.45	GO:0010558	negative regulation of macromolecule biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.54	GO:0003677	DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q01083|SPITZ_DROME
Protein spitz
Search

0.61	GO:0008355	olfactory learning
0.60	GO:0007421	stomatogastric nervous system development
0.60	GO:0007298	border follicle cell migration
0.59	GO:0007438	oenocyte development
0.58	GO:0035225	determination of genital disc primordium
0.58	GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis
0.57	GO:0035277	spiracle morphogenesis, open tracheal system
0.56	GO:0048865	stem cell fate commitment
0.56	GO:0048149	behavioral response to ethanol
0.56	GO:0007391	dorsal closure

0.42

GO:0005154

epidermal growth factor receptor binding

0.51	GO:0005783	endoplasmic reticulum
0.49	GO:0005794	Golgi apparatus
0.38	GO:0005576	extracellular region
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.34	GO:0005886	plasma membrane
0.33	GO:0016607	nuclear speck
0.30	GO:0016021	integral component of membrane

sp|Q01583|DGK1_DROME
Diacylglycerol kinase 1
Search

0.38	Diacylglycerol kinase

0.80	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.59	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation

0.80	GO:0004143	diacylglycerol kinase activity
0.72	GO:0003951	NAD+ kinase activity
0.66	GO:0005509	calcium ion binding
0.52	GO:0030554	adenyl nucleotide binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding

0.44

GO:0005622

intracellular

0.80	EC:2.7.1.107	GO:0004143
0.72	KEGG:R00104	GO:0003951

sp|Q01603|PERO_DROME
Peroxidase
Search

0.41	Animal heme peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0045471	response to ethanol
0.37	GO:0007306	eggshell chorion assembly
0.36	GO:0042744	hydrogen peroxide catabolic process
0.35	GO:0048013	ephrin receptor signaling pathway
0.33	GO:0006468	protein phosphorylation

0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.35	GO:0005003	ephrin receptor activity
0.33	GO:0046872	metal ion binding
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0042600	chorion
0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.72	EC:1.11.1.7	GO:0004601
0.72	KEGG:R03532	GO:0004601

sp|Q01604|PGK_DROME
Phosphoglycerate kinase
Search

0.47	Phosphoglycerate kinase

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.46	GO:0007525	somatic muscle development
0.46	GO:0046716	muscle cell cellular homeostasis
0.46	GO:0007520	myoblast fusion
0.44	GO:0007268	chemical synaptic transmission
0.35	GO:0019319	hexose biosynthetic process
0.35	GO:0006006	glucose metabolic process

0.78	GO:0004618	phosphoglycerate kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008483	transaminase activity
0.33	GO:0019842	vitamin binding
0.33	GO:0050662	coenzyme binding

0.46	GO:0031430	M band
0.45	GO:0030018	Z disc
0.34	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:2.7.2.3	GO:0004618
0.78	KEGG:R01512	GO:0004618

sp|Q01617|CPO_DROME
Protein couch potato
Search

CPO

0.97	Couch potato, isoform O

0.42	GO:0035206	regulation of hemocyte proliferation
0.42	GO:0022611	dormancy process
0.40	GO:0098916	anterograde trans-synaptic signaling
0.38	GO:0007275	multicellular organism development

0.58

GO:0003723

RNA binding

0.37

GO:0005634

nucleus

sp|Q01637|UMPS_DROME
Uridine 5'-monophosphate synthase
Search

0.40	Uridine monophosphate synthetase

0.74	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.73	GO:0044205	'de novo' UMP biosynthetic process
0.41	GO:0006397	mRNA processing
0.41	GO:0090501	RNA phosphodiester bond hydrolysis
0.39	GO:0006468	protein phosphorylation
0.38	GO:0046686	response to cadmium ion
0.38	GO:0016036	cellular response to phosphate starvation
0.36	GO:0043547	positive regulation of GTPase activity
0.34	GO:0032259	methylation
0.34	GO:0006420	arginyl-tRNA aminoacylation

0.79	GO:0004588	orotate phosphoribosyltransferase activity
0.78	GO:0004590	orotidine-5'-phosphate decarboxylase activity
0.41	GO:0004540	ribonuclease activity
0.39	GO:0004672	protein kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005096	GTPase activator activity
0.34	GO:0008168	methyltransferase activity
0.34	GO:0004814	arginine-tRNA ligase activity

0.36	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:2.4.2.10	GO:0004588
0.78	KEGG:R00965	GO:0004590

sp|Q01642|MS84A_DROME
Male-specific sperm protein Mst84Da
Search

0.97	Testis-specific RNA

0.79	GO:0007288	sperm axoneme assembly
0.54	GO:0007275	multicellular organism development
0.42	GO:0003096	renal sodium ion transport
0.39	GO:1902476	chloride transmembrane transport
0.39	GO:0035725	sodium ion transmembrane transport
0.38	GO:0006768	biotin metabolic process
0.37	GO:0072330	monocarboxylic acid biosynthetic process
0.37	GO:0044272	sulfur compound biosynthetic process
0.37	GO:0042364	water-soluble vitamin biosynthetic process
0.36	GO:0009108	coenzyme biosynthetic process

0.40	GO:0015385	sodium:proton antiporter activity
0.39	GO:0015108	chloride transmembrane transporter activity
0.39	GO:0004076	biotin synthase activity
0.37	GO:0005198	structural molecule activity
0.37	GO:0051537	2 iron, 2 sulfur cluster binding
0.37	GO:0051539	4 iron, 4 sulfur cluster binding
0.36	GO:0005506	iron ion binding

0.52	GO:0036126	sperm flagellum
0.41	GO:0005903	brush border
0.30	GO:0016020	membrane

0.39	EC:2.8.1.6	GO:0004076
0.39	KEGG:R01078	GO:0004076

sp|Q01643|MS84B_DROME
Male-specific sperm protein Mst84Db
Search

0.95	Male-specific sperm protein Mst84Db

0.68	GO:0007283	spermatogenesis
0.65	GO:0007281	germ cell development
0.56	GO:0030317	flagellated sperm motility
0.56	GO:0035082	axoneme assembly
0.47	GO:0007275	multicellular organism development
0.42	GO:0001558	regulation of cell growth
0.38	GO:0007018	microtubule-based movement
0.36	GO:0060070	canonical Wnt signaling pathway
0.36	GO:0006457	protein folding
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.43	GO:0005520	insulin-like growth factor binding
0.40	GO:0019904	protein domain specific binding
0.38	GO:0003777	microtubule motor activity
0.36	GO:0051082	unfolded protein binding
0.36	GO:0008013	beta-catenin binding
0.36	GO:0005198	structural molecule activity
0.35	GO:0003713	transcription coactivator activity

0.71	GO:0036126	sperm flagellum
0.53	GO:0044441	ciliary part
0.51	GO:0099513	polymeric cytoskeletal fiber
0.39	GO:0005576	extracellular region
0.38	GO:0005581	collagen trimer
0.38	GO:0016272	prefoldin complex
0.36	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q01644|MS84C_DROME
Male-specific sperm protein Mst84Dc
Search

0.41	Testis-specific RNA

0.70	GO:0007283	spermatogenesis
0.66	GO:0007281	germ cell development
0.58	GO:0030317	flagellated sperm motility
0.57	GO:0035082	axoneme assembly
0.48	GO:0007275	multicellular organism development
0.43	GO:0001558	regulation of cell growth
0.37	GO:0007018	microtubule-based movement

0.44	GO:0005520	insulin-like growth factor binding
0.40	GO:0019904	protein domain specific binding
0.37	GO:0003777	microtubule motor activity
0.36	GO:0005198	structural molecule activity

0.69	GO:0036126	sperm flagellum
0.50	GO:0044441	ciliary part
0.48	GO:0099513	polymeric cytoskeletal fiber
0.40	GO:0005576	extracellular region
0.38	GO:0005581	collagen trimer
0.36	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q01645|MS84D_DROME
Male-specific sperm protein Mst84Dd
Search

0.96	Male-specific sperm protein Mst84Dd

0.69	GO:0007283	spermatogenesis
0.64	GO:0007281	germ cell development
0.58	GO:0030317	flagellated sperm motility
0.58	GO:0035082	axoneme assembly
0.49	GO:0007275	multicellular organism development
0.44	GO:0001558	regulation of cell growth

0.46	GO:0005520	insulin-like growth factor binding
0.40	GO:0019904	protein domain specific binding
0.37	GO:0005198	structural molecule activity

0.69	GO:0036126	sperm flagellum
0.51	GO:0044441	ciliary part
0.49	GO:0099513	polymeric cytoskeletal fiber
0.41	GO:0005576	extracellular region
0.39	GO:0005581	collagen trimer
0.36	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q01819|CONN_DROME
Connectin
Search

0.83

Connectin

0.64	GO:0016200	synaptic target attraction
0.59	GO:0007413	axonal fasciculation
0.54	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.40	GO:0007165	signal transduction
0.40	GO:0033563	dorsal/ventral axon guidance
0.40	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb
0.39	GO:1902284	neuron projection extension involved in neuron projection guidance
0.39	GO:0006955	immune response
0.39	GO:0031290	retinal ganglion cell axon guidance
0.39	GO:0050919	negative chemotaxis

0.40	GO:0048495	Roundabout binding
0.38	GO:0005509	calcium ion binding
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0044295	axonal growth cone
0.58	GO:0031594	neuromuscular junction
0.55	GO:0031225	anchored component of membrane
0.53	GO:0009986	cell surface
0.43	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|Q01820|GCL_DROME
Protein germ cell-less
Search

GCL

0.57	Germ cell-less, isoform B

0.86	GO:0007278	pole cell fate determination
0.85	GO:1902875	regulation of embryonic pattern specification
0.81	GO:0016480	negative regulation of transcription by RNA polymerase III
0.80	GO:0048599	oocyte development
0.80	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.77	GO:0000209	protein polyubiquitination
0.47	GO:0007279	pole cell formation
0.46	GO:0007028	cytoplasm organization
0.46	GO:0008358	maternal determination of anterior/posterior axis, embryo
0.44	GO:0048469	cell maturation

0.75	GO:0060090	molecular adaptor activity
0.36	GO:0042802	identical protein binding

0.78	GO:0031463	Cul3-RING ubiquitin ligase complex
0.77	GO:0034399	nuclear periphery
0.75	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.73	GO:0005643	nuclear pore
0.72	GO:0005938	cell cortex
0.37	GO:0017053	transcriptional repressor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q01842|POK_DROME
Ets DNA-binding protein pokkuri
Search

0.83	Ets DNA-binding protein pokkuri

0.82	GO:0001709	cell fate determination
0.76	GO:0045596	negative regulation of cell differentiation
0.75	GO:0000122	negative regulation of transcription by RNA polymerase II
0.66	GO:0060233	oenocyte delamination
0.64	GO:0045678	positive regulation of R7 cell differentiation
0.64	GO:0007464	R3/R4 cell fate commitment
0.64	GO:2000051	negative regulation of non-canonical Wnt signaling pathway
0.63	GO:0045610	regulation of hemocyte differentiation
0.61	GO:0042659	regulation of cell fate specification
0.61	GO:0007298	border follicle cell migration

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0019904	protein domain specific binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.61	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0016757

sp|Q01989|MYS9_DROME
Myosin heavy chain 95F
Search

0.74	Unconventional myosin-VI

0.74	GO:0007018	microtubule-based movement
0.37	GO:0019749	cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte
0.36	GO:0030589	pseudocleavage involved in syncytial blastoderm formation
0.36	GO:0045175	basal protein localization
0.36	GO:0045167	asymmetric protein localization involved in cell fate determination
0.36	GO:0008363	larval chitin-based cuticle development
0.36	GO:0045217	cell-cell junction maintenance
0.36	GO:0016333	morphogenesis of follicular epithelium
0.36	GO:0007291	sperm individualization
0.36	GO:0055059	asymmetric neuroblast division

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0032403	protein complex binding
0.37	GO:0070856	myosin VI light chain binding
0.36	GO:0016887	ATPase activity
0.36	GO:0000146	microfilament motor activity

0.77	GO:0016459	myosin complex
0.36	GO:0070865	investment cone
0.36	GO:0045172	germline ring canal
0.36	GO:0031941	filamentous actin
0.36	GO:0045178	basal part of cell
0.36	GO:0030426	growth cone
0.35	GO:0030139	endocytic vesicle
0.35	GO:0005875	microtubule associated complex
0.35	GO:0005938	cell cortex
0.34	GO:0005829	cytosol

0.36

GO:0016887

sp|Q02280|KCNAE_DROME
Potassium voltage-gated channel protein eag
Search

0.86	Potassium voltage-gated channel protein eag

0.73	GO:0071804	cellular potassium ion transport
0.70	GO:0034765	regulation of ion transmembrane transport
0.63	GO:0023014	signal transduction by protein phosphorylation
0.62	GO:0098662	inorganic cation transmembrane transport
0.60	GO:0000160	phosphorelay signal transduction system
0.39	GO:0042391	regulation of membrane potential
0.38	GO:0048150	behavioral response to ether
0.37	GO:0042066	perineurial glial growth
0.37	GO:0007619	courtship behavior
0.36	GO:0007612	learning

0.77	GO:0005249	voltage-gated potassium channel activity
0.63	GO:0000155	phosphorelay sensor kinase activity
0.34	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0034705	potassium channel complex

0.63

EC:2.7.3

GO:0000155

sp|Q02308|HLES_DROME
Protein hairless
Search

0.85	GO:0016360	sensory organ precursor cell fate determination
0.85	GO:0044719	regulation of imaginal disc-derived wing size
0.85	GO:0036335	intestinal stem cell homeostasis
0.84	GO:0048190	wing disc dorsal/ventral pattern formation
0.84	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.84	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.82	GO:0035019	somatic stem cell population maintenance
0.70	GO:0010941	regulation of cell death
0.68	GO:1903507	negative regulation of nucleic acid-templated transcription
0.36	GO:0099139	cheating during chimeric sorocarp development

0.77	GO:0003714	transcription corepressor activity
0.39	GO:0003723	RNA binding
0.34	GO:0035091	phosphatidylinositol binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.35	GO:0042641	actomyosin
0.35	GO:0005771	multivesicular body
0.35	GO:0031594	neuromuscular junction
0.35	GO:0005769	early endosome
0.30	GO:0016020	membrane
0.30	GO:0043231	intracellular membrane-bounded organelle

0.32

GO:0016787

sp|Q02360|FD2_DROME
Fork head domain-containing protein FD2
Search

0.89	Fork head domain-containing protein FD2

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0010604	positive regulation of macromolecule metabolic process
0.44	GO:0030154	cell differentiation
0.44	GO:0009653	anatomical structure morphogenesis
0.43	GO:0006351	transcription, DNA-templated
0.38	GO:0007275	multicellular organism development
0.37	GO:0032275	luteinizing hormone secretion
0.36	GO:0061448	connective tissue development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0008301	DNA binding, bending
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0042302	structural constituent of cuticle
0.34	GO:0001106	RNA polymerase II transcription corepressor activity
0.32	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|Q02361|FD3_DROME
Fork head domain-containing protein FD3
Search

0.70	Fork head domain-containing protein FD3

0.57	GO:0006355	regulation of transcription, DNA-templated
0.45	GO:0009653	anatomical structure morphogenesis
0.44	GO:0030154	cell differentiation
0.42	GO:0007275	multicellular organism development
0.42	GO:0009888	tissue development
0.40	GO:1903508	positive regulation of nucleic acid-templated transcription
0.40	GO:0010628	positive regulation of gene expression
0.40	GO:0006351	transcription, DNA-templated
0.38	GO:1903507	negative regulation of nucleic acid-templated transcription
0.38	GO:2000113	negative regulation of cellular macromolecule biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0008301	DNA binding, bending
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0001106	RNA polymerase II transcription corepressor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q02427|RBP1_DROME
RNA-binding protein 1
Search

0.38	RNA-binding protein 1

0.48	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.47	GO:0031440	regulation of mRNA 3'-end processing
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.43	GO:0045292	mRNA cis splicing, via spliceosome
0.34	GO:0007163	establishment or maintenance of cell polarity
0.33	GO:0006468	protein phosphorylation
0.33	GO:0035556	intracellular signal transduction

0.59	GO:0003723	RNA binding
0.38	GO:0008270	zinc ion binding
0.34	GO:0004697	protein kinase C activity
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0035327	transcriptionally active chromatin
0.39	GO:0005634	nucleus
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.11.13

GO:0004697

sp|Q02637|CEBP_DROME
CCAAT/enhancer-binding protein
Search

SLBO

0.91	Slow border cells

0.60	GO:0007298	border follicle cell migration
0.60	GO:0046427	positive regulation of JAK-STAT cascade
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.39	GO:0030097	hemopoiesis
0.39	GO:0001708	cell fate specification

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.40	GO:0046982	protein heterodimerization activity
0.39	GO:0000987	proximal promoter sequence-specific DNA binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity
0.33	GO:0004601	peroxidase activity
0.33	GO:0004677	DNA-dependent protein kinase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0030554	adenyl nucleotide binding

0.48	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:1.11.1.12	GO:0047066
0.33	KEGG:R03532	GO:0004601

sp|Q02645|HTS_DROME
Protein hu-li tai shao
Search

0.65	Protein hu-li tai shao

0.67	GO:0007264	small GTPase mediated signal transduction
0.64	GO:0030724	testicular fusome organization
0.64	GO:0008302	female germline ring canal formation, actin assembly
0.60	GO:0030723	ovarian fusome organization
0.60	GO:0007527	adult somatic muscle development
0.60	GO:0007282	cystoblast division
0.59	GO:0072499	photoreceptor cell axon guidance
0.59	GO:0048135	female germ-line cyst formation
0.59	GO:0007294	germarium-derived oocyte fate determination
0.58	GO:0065009	regulation of molecular function

0.66	GO:0005085	guanyl-nucleotide exchange factor activity
0.51	GO:0003779	actin binding

0.61	GO:0035183	female germline ring canal inner rim
0.60	GO:0045170	spectrosome
0.58	GO:0045169	fusome
0.57	GO:0016328	lateral plasma membrane
0.55	GO:0005884	actin filament
0.30	GO:0031224	intrinsic component of membrane

sp|Q02748|IF4A_DROME
Eukaryotic initiation factor 4A
Search

0.37	DEAD box ATP-dependent RNA helicase

0.70	GO:0006413	translational initiation
0.45	GO:0007279	pole cell formation
0.45	GO:0048132	female germ-line stem cell asymmetric division
0.44	GO:0030718	germ-line stem cell population maintenance
0.43	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.37	GO:0010501	RNA secondary structure unwinding
0.35	GO:0007446	imaginal disc growth
0.35	GO:0002168	instar larval development
0.35	GO:0002181	cytoplasmic translation
0.34	GO:0000278	mitotic cell cycle

0.76	GO:0004004	ATP-dependent RNA helicase activity
0.71	GO:0003743	translation initiation factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0005515	protein binding
0.33	GO:0016779	nucleotidyltransferase activity
0.33	GO:0003746	translation elongation factor activity
0.32	GO:0003677	DNA binding

0.43	GO:0043186	P granule
0.36	GO:0005730	nucleolus
0.35	GO:0016281	eukaryotic translation initiation factor 4F complex
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7

GO:0016779

sp|Q02870|ERCC3_DROME
DNA excision repair protein haywire
Search

0.39	General transcription and DNA repair factor IIH helicase subunit XPB

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.73	GO:0006289	nucleotide-excision repair
0.70	GO:0032392	DNA geometric change
0.48	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.47	GO:0007064	mitotic sister chromatid cohesion
0.46	GO:0009411	response to UV
0.45	GO:0040008	regulation of growth
0.45	GO:0042127	regulation of cell proliferation
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.72	GO:0004003	ATP-dependent DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0043138	3'-5' DNA helicase activity
0.34	GO:0000990	transcription factor activity, core RNA polymerase binding

0.47	GO:0031390	Ctf18 RFC-like complex
0.47	GO:0005675	holo TFIIH complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q02910|CPN_DROME
Calphotin
Search

0.85

Calphotin

0.53	GO:0051208	sequestering of calcium ion
0.52	GO:0042052	rhabdomere development
0.41	GO:0007601	visual perception
0.36	GO:0050896	response to stimulus
0.34	GO:0006413	translational initiation
0.34	GO:0010466	negative regulation of peptidase activity
0.34	GO:0071897	DNA biosynthetic process
0.34	GO:0009306	protein secretion
0.33	GO:0006260	DNA replication
0.33	GO:0046856	phosphatidylinositol dephosphorylation

0.65	GO:0005509	calcium ion binding
0.36	GO:0042834	peptidoglycan binding
0.34	GO:0003743	translation initiation factor activity
0.34	GO:0017076	purine nucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032553	ribonucleotide binding
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0030414	peptidase inhibitor activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding

0.49	GO:0044297	cell body
0.49	GO:0030424	axon
0.43	GO:0016028	rhabdomere
0.42	GO:0005791	rough endoplasmic reticulum
0.37	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.34	GO:0005576	extracellular region
0.34	GO:0009360	DNA polymerase III complex
0.33	GO:0030313	cell envelope
0.33	GO:0019867	outer membrane

0.34

GO:0003887

sp|Q02926|RB97D_DROME
Ribonucleoprotein RB97D
Search

RB97D

0.71	RNA-binding protein musashi

0.46	GO:0001745	compound eye morphogenesis
0.46	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.43	GO:0022414	reproductive process
0.41	GO:0061458	reproductive system development
0.41	GO:0042594	response to starvation
0.41	GO:0009408	response to heat
0.41	GO:0032504	multicellular organism reproduction
0.40	GO:0036099	female germ-line stem cell population maintenance
0.40	GO:0033119	negative regulation of RNA splicing
0.39	GO:0030154	cell differentiation

0.59	GO:0003723	RNA binding
0.40	GO:0043565	sequence-specific DNA binding
0.33	GO:0051082	unfolded protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005215	transporter activity

0.48	GO:0019013	viral nucleocapsid
0.47	GO:0005703	polytene chromosome puff
0.46	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0035062	omega speckle
0.42	GO:0000792	heterochromatin
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q02936|HH_DROME
Protein hedgehog
Search

0.74	Sonic hedgehog

0.74	GO:0016539	intein-mediated protein splicing
0.73	GO:0007267	cell-cell signaling
0.69	GO:0007275	multicellular organism development
0.60	GO:0007228	positive regulation of hh target transcription factor activity
0.56	GO:0045165	cell fate commitment
0.56	GO:0007498	mesoderm development
0.55	GO:0001667	ameboidal-type cell migration
0.55	GO:0007548	sex differentiation
0.55	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.55	GO:0002009	morphogenesis of an epithelium

0.59	GO:0008233	peptidase activity
0.56	GO:0016015	morphogen activity
0.52	GO:0005113	patched binding
0.50	GO:0043237	laminin-1 binding
0.49	GO:0046872	metal ion binding
0.45	GO:0005539	glycosaminoglycan binding
0.38	GO:0005119	smoothened binding
0.34	GO:0003856	3-dehydroquinate synthase activity
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0015078	hydrogen ion transmembrane transporter activity

0.67	GO:0005615	extracellular space
0.52	GO:0005886	plasma membrane
0.49	GO:0030139	endocytic vesicle
0.47	GO:0005768	endosome
0.46	GO:0098857	membrane microdomain
0.44	GO:0005578	proteinaceous extracellular matrix
0.44	GO:0009986	cell surface
0.43	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.34	GO:0005788	endoplasmic reticulum lumen

0.59	EC:3.4	GO:0008233
0.34	KEGG:R03083	GO:0003856

sp|Q03017|CACT_DROME
NF-kappa-B inhibitor cactus
Search

CACT

0.39	NF-kappa-B inhibitor cactus

0.87	GO:0002810	regulation of antifungal peptide biosynthetic process
0.86	GO:0002804	positive regulation of antifungal peptide production
0.86	GO:0002807	positive regulation of antimicrobial peptide biosynthetic process
0.85	GO:0019732	antifungal humoral response
0.84	GO:0009950	dorsal/ventral axis specification
0.72	GO:0007399	nervous system development
0.53	GO:0046843	dorsal appendage formation
0.46	GO:0008063	Toll signaling pathway
0.44	GO:0030097	hemopoiesis
0.44	GO:0045087	innate immune response

0.42	GO:0008134	transcription factor binding
0.35	GO:0005216	ion channel activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0005524	ATP binding
0.32	GO:0046872	metal ion binding

0.83	GO:0031594	neuromuscular junction
0.48	GO:0005737	cytoplasm
0.35	GO:1905369	endopeptidase complex
0.34	GO:0043234	protein complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0032440

sp|Q03019|TWINE_DROME
Cdc25-like protein phosphatase twine
Search

0.56	M-phase inducer phosphatase

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:0051078	meiotic nuclear envelope disassembly
0.57	GO:0007348	regulation of syncytial blastoderm mitotic cell cycle
0.53	GO:0007140	male meiotic nuclear division
0.52	GO:0051445	regulation of meiotic cell cycle
0.51	GO:0007283	spermatogenesis
0.41	GO:0051301	cell division
0.41	GO:0044839	cell cycle G2/M phase transition
0.40	GO:0044771	meiotic cell cycle phase transition

0.75	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.37	GO:0005515	protein binding
0.34	GO:0004792	thiosulfate sulfurtransferase activity
0.32	GO:0003676	nucleic acid binding

0.50	GO:0005819	spindle
0.44	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005813	centrosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.75	EC:3.1.3.48	GO:0004725
0.34	KEGG:R01931	GO:0004792

sp|Q03042|KGP1_DROME
cGMP-dependent protein kinase, isozyme 1
Search

PRKG2

0.82	cGMP-dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.52	GO:0007526	larval somatic muscle development
0.35	GO:2001226	negative regulation of chloride transport
0.34	GO:0072659	protein localization to plasma membrane
0.34	GO:0018209	peptidyl-serine modification
0.34	GO:0055085	transmembrane transport

0.85	GO:0004692	cGMP-dependent protein kinase activity
0.71	GO:0030553	cGMP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.34	GO:0042803	protein homodimerization activity

0.37	GO:0005737	cytoplasm
0.34	GO:0031965	nuclear membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.7.11.12

GO:0004692

sp|Q03043|KGP24_DROME
cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B
Search

0.61	cGMP-dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.49	GO:0030536	larval feeding behavior
0.48	GO:0046959	habituation
0.48	GO:0008345	larval locomotory behavior
0.48	GO:0007614	short-term memory
0.48	GO:0032095	regulation of response to food
0.47	GO:0009744	response to sucrose
0.47	GO:0007616	long-term memory
0.47	GO:0008045	motor neuron axon guidance
0.46	GO:0030510	regulation of BMP signaling pathway

0.85	GO:0004692	cGMP-dependent protein kinase activity
0.67	GO:0030553	cGMP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008603	cAMP-dependent protein kinase regulator activity

0.38	GO:0005886	plasma membrane
0.36	GO:0005737	cytoplasm
0.34	GO:0005952	cAMP-dependent protein kinase complex
0.30	GO:0016021	integral component of membrane

0.85

EC:2.7.11.12

GO:0004692

sp|Q03334|RS13_DROME
40S ribosomal protein S13
Search

RPS13

0.65	Ribosomal protein S13

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.40	GO:0033119	negative regulation of RNA splicing
0.34	GO:0048015	phosphatidylinositol-mediated signaling
0.34	GO:0046854	phosphatidylinositol phosphorylation

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0070181	small ribosomal subunit rRNA binding
0.39	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0016301	kinase activity

0.61	GO:0005840	ribosome
0.44	GO:0005730	nucleolus
0.40	GO:0000228	nuclear chromosome
0.40	GO:0044445	cytosolic part
0.30	GO:0031224	intrinsic component of membrane

sp|Q03372|HMSH_DROME
Muscle segmentation homeobox
Search

0.72	Muscle segmentation homeobox

0.57	GO:0035309	wing and notum subfield formation
0.56	GO:0007485	imaginal disc-derived male genitalia development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007450	dorsal/ventral pattern formation, imaginal disc
0.55	GO:0035222	wing disc pattern formation
0.55	GO:0042659	regulation of cell fate specification
0.54	GO:0021782	glial cell development
0.54	GO:0007476	imaginal disc-derived wing morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.36	GO:0002039	p53 binding
0.34	GO:0035326	enhancer binding
0.34	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0001012	RNA polymerase II regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q03427|LAMC_DROME
Lamin-C
Search

0.88	Nuclear envelope protein lamin

0.46	GO:0007112	male meiosis cytokinesis
0.46	GO:0031081	nuclear pore distribution
0.46	GO:0070870	heterochromatin maintenance involved in chromatin silencing
0.46	GO:1905832	positive regulation of spindle assembly
0.45	GO:0007110	meiosis I cytokinesis
0.45	GO:0007430	terminal branching, open tracheal system
0.45	GO:0048137	spermatocyte division
0.45	GO:2000433	positive regulation of cytokinesis, actomyosin contractile ring assembly
0.45	GO:0071763	nuclear membrane organization
0.45	GO:0035262	gonad morphogenesis

0.62	GO:0005198	structural molecule activity
0.41	GO:0005102	receptor binding

0.79	GO:0005882	intermediate filament
0.48	GO:0070732	spindle envelope
0.46	GO:0005652	nuclear lamina
0.43	GO:0005635	nuclear envelope
0.37	GO:0036338	viral membrane
0.34	GO:0000922	spindle pole
0.33	GO:0019866	organelle inner membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q03445|GLR1_DROME
Glutamate receptor 1
Search

0.68	Glutamate receptor 1

0.76	GO:0060079	excitatory postsynaptic potential
0.74	GO:0035235	ionotropic glutamate receptor signaling pathway
0.56	GO:0006811	ion transport
0.42	GO:0055085	transmembrane transport
0.34	GO:0009253	peptidoglycan catabolic process
0.33	GO:0006396	RNA processing

0.78	GO:0005234	extracellularly glutamate-gated ion channel activity
0.74	GO:0004970	ionotropic glutamate receptor activity
0.54	GO:0099094	ligand-gated cation channel activity
0.54	GO:0005272	sodium channel activity
0.52	GO:0098782	mechanosensitived potassium channel activity
0.34	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.34	GO:0061783	peptidoglycan muralytic activity
0.33	GO:0019239	deaminase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003723	RNA binding

0.75	GO:0045211	postsynaptic membrane
0.70	GO:0030054	cell junction
0.42	GO:0008328	ionotropic glutamate receptor complex
0.38	GO:0034703	cation channel complex

0.34

EC:3.5

GO:0016810

sp|Q03720|SLO_DROME
Calcium-activated potassium channel slowpoke
Search

SLO

0.91	Calcium-activated potassium channel slowpoke

0.73	GO:0071804	cellular potassium ion transport
0.62	GO:0098662	inorganic cation transmembrane transport
0.37	GO:1900074	negative regulation of neuromuscular synaptic transmission
0.37	GO:0045433	male courtship behavior, veined wing generated song production
0.36	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.36	GO:0048512	circadian behavior
0.35	GO:0034765	regulation of ion transmembrane transport
0.34	GO:0042493	response to drug

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.78	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0043025	neuronal cell body
0.35	GO:0043005	neuron projection

sp|Q03751|DNJC5_DROME
DnaJ homolog subfamily C member 5 homolog
Search

0.44	Molecular chaperone

0.47	GO:1900073	regulation of neuromuscular synaptic transmission
0.46	GO:0070050	neuron cellular homeostasis
0.45	GO:1903035	negative regulation of response to wounding
0.45	GO:0016079	synaptic vesicle exocytosis
0.41	GO:0006457	protein folding
0.38	GO:0006413	translational initiation
0.37	GO:0006811	ion transport
0.36	GO:0055085	transmembrane transport
0.36	GO:0006508	proteolysis
0.35	GO:0007165	signal transduction

0.41	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0003743	translation initiation factor activity
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0099600	transmembrane receptor activity
0.36	GO:0038023	signaling receptor activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0003677	DNA binding

0.48	GO:0061177	type Is terminal bouton
0.47	GO:0061176	type Ib terminal bouton
0.44	GO:0008021	synaptic vesicle
0.37	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.37

GO:0004252

sp|Q04047|NONA_DROME
Protein no-on-transient A
Search

NONA

0.89	Splicing factor proline-and glutamine-rich

0.46	GO:0045433	male courtship behavior, veined wing generated song production
0.43	GO:0007601	visual perception
0.40	GO:0000398	mRNA splicing, via spliceosome
0.38	GO:0042331	phototaxis
0.38	GO:0007632	visual behavior
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0051028	mRNA transport

0.58	GO:0003723	RNA binding
0.38	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.32	GO:0008186	RNA-dependent ATPase activity
0.32	GO:0004540	ribonuclease activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005634	nucleus
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0044446	intracellular organelle part
0.34	GO:1902494	catalytic complex
0.33	GO:0005856	cytoskeleton
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q04164|SAS_DROME
Putative epidermal cell surface receptor
Search

0.65	Putative epidermal cell surface receptor

0.51	GO:0002168	instar larval development
0.48	GO:0007411	axon guidance
0.37	GO:0007162	negative regulation of cell adhesion
0.32	GO:0006508	proteolysis
0.32	GO:0006030	chitin metabolic process

0.33	GO:0005509	calcium ion binding
0.32	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity
0.32	GO:0008061	chitin binding
0.30	GO:0004872	receptor activity

0.48	GO:0016324	apical plasma membrane
0.35	GO:0048188	Set1C/COMPASS complex
0.32	GO:0009277	fungal-type cell wall
0.31	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane
0.30	GO:0031226	intrinsic component of plasma membrane

sp|Q04448|MTDC_DROME
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
Search

0.38	Methylenetetrahydrofolate dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.44	GO:0046653	tetrahydrofolate metabolic process
0.43	GO:0006730	one-carbon metabolic process
0.38	GO:0009086	methionine biosynthetic process
0.38	GO:0000105	histidine biosynthetic process
0.38	GO:0072522	purine-containing compound biosynthetic process
0.37	GO:0009165	nucleotide biosynthetic process
0.36	GO:0006163	purine nucleotide metabolic process
0.34	GO:0043648	dicarboxylic acid metabolic process
0.34	GO:0006144	purine nucleobase metabolic process

0.79	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.50	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity
0.47	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity
0.43	GO:0042301	phosphate ion binding
0.41	GO:0004329	formate-tetrahydrofolate ligase activity
0.39	GO:0000287	magnesium ion binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005739	mitochondrion
0.39	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.79	EC:1.5.1.5	GO:0004488
0.79	KEGG:R01220	GO:0004488

sp|Q04499|PROD_DROME
Proline dehydrogenase 1, mitochondrial
Search

0.56	Proline dehydrogenase

0.79	GO:0006562	proline catabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0042331	phototaxis
0.41	GO:0007626	locomotory behavior
0.37	GO:0006536	glutamate metabolic process
0.34	GO:0043650	dicarboxylic acid biosynthetic process
0.34	GO:0009084	glutamine family amino acid biosynthetic process

0.80	GO:0004657	proline dehydrogenase activity
0.37	GO:0071949	FAD binding
0.34	GO:0005509	calcium ion binding

0.38	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.80

EC:1.5.99.8

GO:0004657

sp|Q04652|KELC_DROME
Ring canal kelch protein
Search

KEL

0.49	Ring canal kelch homolog

0.76	GO:0007301	female germline ring canal formation
0.76	GO:0030723	ovarian fusome organization
0.74	GO:0030717	karyosome formation
0.71	GO:0007349	cellularization
0.61	GO:0030036	actin cytoskeleton organization
0.60	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.53	GO:0072156	distal tubule morphogenesis
0.53	GO:0070294	renal sodium ion absorption
0.50	GO:0070936	protein K48-linked ubiquitination
0.45	GO:0050801	ion homeostasis

0.69	GO:0003779	actin binding
0.54	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0042802	identical protein binding

0.75	GO:0035324	female germline ring canal
0.67	GO:0031463	Cul3-RING ubiquitin ligase complex
0.53	GO:0005856	cytoskeleton
0.45	GO:0005829	cytosol
0.37	GO:0001726	ruffle
0.37	GO:0030027	lamellipodium
0.30	GO:0016020	membrane

0.54

GO:0004842

sp|Q04688|ELG_DROME
DNA-binding protein Ets97D
Search

0.67	GA binding protein transcription factor alpha subunit

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0045653	negative regulation of megakaryocyte differentiation
0.42	GO:1903351	cellular response to dopamine
0.42	GO:0032502	developmental process
0.40	GO:0006366	transcription by RNA polymerase II
0.39	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0032501	multicellular organismal process
0.38	GO:1902679	negative regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.41	GO:0033613	activating transcription factor binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003682	chromatin binding
0.39	GO:0046982	protein heterodimerization activity
0.39	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0000785	chromatin
0.38	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q04691|FBP1_DROME
Fat-body protein 1
Search

0.95	Fat-body protein 1

0.86	GO:0015032	storage protein import into fat body
0.40	GO:0055114	oxidation-reduction process
0.33	GO:0006508	proteolysis

0.67	GO:0008565	protein transporter activity
0.40	GO:0016491	oxidoreductase activity
0.40	GO:0046872	metal ion binding
0.34	GO:0004198	calcium-dependent cysteine-type endopeptidase activity

0.32

GO:0005622

intracellular

0.40

GO:0016491

sp|Q04787|BSH_DROME
Brain-specific homeobox protein
Search

0.76	Brain-specific homeobox protein, putative

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048663	neuron fate commitment
0.54	GO:0048513	animal organ development
0.53	GO:0060322	head development
0.53	GO:0007417	central nervous system development
0.49	GO:0042755	eating behavior
0.47	GO:0007626	locomotory behavior
0.47	GO:0048771	tissue remodeling

0.65	GO:0043565	sequence-specific DNA binding
0.41	GO:0003700	DNA binding transcription factor activity
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding
0.33	GO:0030545	receptor regulator activity

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q05192|FTF1B_DROME
Nuclear hormone receptor FTZ-F1 beta
Search

0.84	Nuclear hormone receptor FTZ-F1 beta

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.62	GO:0035211	spermathecum morphogenesis
0.60	GO:0045433	male courtship behavior, veined wing generated song production
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.56	GO:0030522	intracellular receptor signaling pathway
0.44	GO:0009888	tissue development
0.43	GO:1902680	positive regulation of RNA biosynthetic process

0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.43	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding
0.34	GO:0005543	phospholipid binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

0.61	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.38	GO:0044446	intracellular organelle part
0.32	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0016705

sp|Q05201|EYA_DROME
Developmental protein eyes absent
Search

0.70	Developmental protein eyes absent

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.69	GO:0007275	multicellular organism development
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0001744	optic lobe placode formation
0.56	GO:0070285	pigment cell development
0.54	GO:0009996	negative regulation of cell fate specification
0.53	GO:0007525	somatic muscle development
0.53	GO:0007498	mesoderm development
0.52	GO:0030707	ovarian follicle cell development
0.51	GO:0002009	morphogenesis of an epithelium

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0046872	metal ion binding
0.53	GO:0001105	RNA polymerase II transcription coactivator activity
0.47	GO:0008134	transcription factor binding
0.35	GO:0003723	RNA binding

0.46	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0032993	protein-DNA complex
0.35	GO:0044446	intracellular organelle part
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.75

GO:0004725

sp|Q05319|STUB_DROME
Serine proteinase stubble
Search

0.44	Clip-domain serine protease

0.60	GO:0006508	proteolysis
0.52	GO:0035220	wing disc development
0.52	GO:0051017	actin filament bundle assembly
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.32	GO:0006030	chitin metabolic process
0.31	GO:0005975	carbohydrate metabolic process

0.68	GO:0004252	serine-type endopeptidase activity
0.32	GO:0003677	DNA binding
0.32	GO:0008061	chitin binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0004872	receptor activity

0.34	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.68

GO:0004252

sp|Q05337|GNAF_DROME
Guanine nucleotide-binding protein G(f) subunit alpha
Search

0.63	GTP binding regulatory protein Gs alpha S chain

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0035208	positive regulation of hemocyte proliferation
0.51	GO:0051489	regulation of filopodium assembly
0.50	GO:0007498	mesoderm development
0.40	GO:0019933	cAMP-mediated signaling
0.39	GO:1900195	positive regulation of oocyte maturation
0.39	GO:0032501	multicellular organismal process
0.38	GO:2000292	regulation of defecation
0.38	GO:0090038	negative regulation of protein kinase C signaling
0.37	GO:0071695	anatomical structure maturation

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0019001	guanyl nucleotide binding
0.65	GO:0032550	purine ribonucleoside binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0001664	G-protein coupled receptor binding
0.34	GO:0046872	metal ion binding
0.33	GO:0003896	DNA primase activity

0.41	GO:1905360	GTPase complex
0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0098797	plasma membrane protein complex
0.34	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7

GO:0003896

sp|Q05344|SSRP1_DROME
FACT complex subunit Ssrp1
Search

0.76	FACT complex subunit SSRP1

0.65	GO:0006260	DNA replication
0.64	GO:0006281	DNA repair
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0001672	regulation of chromatin assembly or disassembly
0.36	GO:0030707	ovarian follicle cell development
0.36	GO:0051101	regulation of DNA binding
0.35	GO:0030838	positive regulation of actin filament polymerization

0.55	GO:0003677	DNA binding
0.41	GO:0003682	chromatin binding
0.37	GO:0070087	chromo shadow domain binding
0.36	GO:0043621	protein self-association
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0044877	macromolecular complex binding
0.34	GO:0031072	heat shock protein binding
0.33	GO:0051082	unfolded protein binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0030554	adenyl nucleotide binding

0.67	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part

0.32

GO:0016491

sp|Q05547|PP13_DROME
Serine/threonine-protein phosphatase alpha-3 isoform
Search

0.52	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.45	GO:0046692	sperm competition
0.44	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.42	GO:0008355	olfactory learning
0.41	GO:0008542	visual learning
0.41	GO:0007080	mitotic metaphase plate congression
0.41	GO:0008344	adult locomotory behavior
0.40	GO:0051225	spindle assembly
0.40	GO:0048477	oogenesis
0.40	GO:0007411	axon guidance

0.76	GO:0004722	protein serine/threonine phosphatase activity
0.54	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.33	GO:0050661	NADP binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0051287	NAD binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.54	GO:0072357	PTW/PP1 phosphatase complex
0.41	GO:0005700	polytene chromosome
0.35	GO:0005829	cytosol
0.35	GO:0020036	Maurer's cleft
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.2.1

GO:0016620

sp|Q05652|KPEL_DROME
Serine/threonine-protein kinase pelle
Search

0.55	Serine/threonine-protein kinase pelle

0.63	GO:0006468	protein phosphorylation
0.59	GO:0007352	zygotic specification of dorsal/ventral axis
0.57	GO:0007526	larval somatic muscle development
0.57	GO:0019732	antifungal humoral response
0.57	GO:0048262	determination of dorsal/ventral asymmetry
0.51	GO:0007154	cell communication
0.51	GO:0023052	signaling
0.49	GO:0051716	cellular response to stimulus
0.46	GO:0065007	biological regulation
0.39	GO:0035172	hemocyte proliferation

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0019904	protein domain specific binding
0.47	GO:0030246	carbohydrate binding
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0001871	pattern binding
0.33	GO:0004842	ubiquitin-protein transferase activity

0.42	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33	EC:3.2.1	GO:0004553
0.33	KEGG:R03876	GO:0004842

sp|Q05733|DCHS_DROME
Histidine decarboxylase
Search

0.61	Aromatic amino acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.49	GO:0001694	histamine biosynthetic process
0.48	GO:0043052	thermotaxis
0.44	GO:0052805	imidazole-containing compound catabolic process
0.41	GO:0046395	carboxylic acid catabolic process
0.39	GO:0042423	catecholamine biosynthetic process
0.35	GO:1903818	positive regulation of voltage-gated potassium channel activity
0.35	GO:0032222	regulation of synaptic transmission, cholinergic
0.35	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.35	GO:0030431	sleep

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0070279	vitamin B6 binding
0.60	GO:0050662	coenzyme binding
0.53	GO:0043168	anion binding
0.35	GO:0051861	glycolipid binding
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0043177	organic acid binding
0.33	GO:0016874	ligase activity

0.34	GO:0031225	anchored component of membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane

0.68

EC:4.1.1

GO:0016831

sp|Q05783|HMGD_DROME
High mobility group protein D
Search

0.95	High mobility group protein D

0.49	GO:0006260	DNA replication
0.48	GO:0006281	DNA repair
0.46	GO:0006325	chromatin organization
0.45	GO:0006351	transcription, DNA-templated
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.39	GO:0001672	regulation of chromatin assembly or disassembly
0.38	GO:0030707	ovarian follicle cell development
0.38	GO:0051101	regulation of DNA binding

0.55	GO:0003677	DNA binding
0.39	GO:0070087	chromo shadow domain binding
0.38	GO:0043621	protein self-association
0.38	GO:0031491	nucleosome binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0001026	TFIIIB-type transcription factor activity
0.34	GO:0031072	heat shock protein binding
0.33	GO:0001156	TFIIIC-class transcription factor binding
0.33	GO:0051082	unfolded protein binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.54	GO:0005694	chromosome
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005829	cytosol
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.32

GO:0003887

sp|Q05825|ATPB_DROME
ATP synthase subunit beta, mitochondrial
Search

0.43	ATP synthase subunit beta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration
0.34	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.34	GO:0051453	regulation of intracellular pH
0.34	GO:0001525	angiogenesis
0.33	GO:0030163	protein catabolic process
0.33	GO:0006629	lipid metabolic process

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.35	GO:0043532	angiostatin binding
0.35	GO:0042288	MHC class I protein binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.35	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0042645	mitochondrial nucleoid
0.34	GO:0043209	myelin sheath
0.34	GO:0009986	cell surface
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q05856|RSMB_DROME
Small nuclear ribonucleoprotein-associated protein B
Search

0.84	Small nuclear ribonucleoprotein-associated protein B

0.46	GO:0008406	gonad development
0.46	GO:0007283	spermatogenesis
0.45	GO:0007281	germ cell development
0.42	GO:0006367	transcription initiation from RNA polymerase II promoter
0.41	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0022618	ribonucleoprotein complex assembly
0.36	GO:0008213	protein alkylation
0.35	GO:0043414	macromolecule methylation
0.34	GO:0008334	histone mRNA metabolic process
0.34	GO:0006369	termination of RNA polymerase II transcription

0.53	GO:0003723	RNA binding
0.41	GO:0046982	protein heterodimerization activity
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0004518	nuclease activity
0.33	GO:0008270	zinc ion binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.57	GO:0019013	viral nucleocapsid
0.56	GO:0005634	nucleus
0.47	GO:0045495	pole plasm
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0120114	Sm-like protein family complex
0.41	GO:0044446	intracellular organelle part
0.38	GO:1902494	catalytic complex
0.35	GO:0005829	cytosol
0.34	GO:0043234	protein complex

0.33

EC:3.1

GO:0004518

tr|Q058X1|Q058X1_DROME
IP13351p
Search

0.61	endoplasmic reticulum metallopeptidase 1

0.30

GO:0044425

membrane part

tr|Q058Y4|Q058Y4_DROME
IP10855p
Search

0.30

GO:0044425

membrane part

tr|Q058Z8|Q058Z8_DROME
GEO11848p1
Search

sp|Q05913|T2FA_DROME
General transcription factor IIF subunit 1
Search

GTF2F1

0.83	Transcription initiation factor TFIIF subunit alpha

0.81	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.51	GO:0006368	transcription elongation from RNA polymerase II promoter
0.44	GO:0006413	translational initiation
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0006508	proteolysis

0.57	GO:0001096	TFIIF-class transcription factor binding
0.55	GO:0003677	DNA binding
0.44	GO:0003743	translation initiation factor activity
0.34	GO:0005549	odorant binding
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0016740	transferase activity

0.61	GO:0005634	nucleus
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.48	GO:0005667	transcription factor complex
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016491

tr|Q059A4|Q059A4_DROME
CG4627
Search

LOC108087785

0.86	transmembrane protein 186 isoform X1

0.34

GO:0006508

proteolysis

0.34

GO:0008233

peptidase activity

0.30

GO:0044425

membrane part

0.34

GO:0008233

tr|Q059A6|Q059A6_DROME
GEO11841p1
Search

sp|Q06003|GOLI_DROME
Protein goliath
Search

RNF149

0.55	Ring finger protein 130

0.42	GO:0043409	negative regulation of MAPK cascade
0.42	GO:0035690	cellular response to drug
0.42	GO:0031647	regulation of protein stability
0.41	GO:0016567	protein ubiquitination
0.37	GO:0001707	mesoderm formation
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0010469	regulation of receptor activity

0.42	GO:0061630	ubiquitin protein ligase activity
0.40	GO:0016874	ligase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003677	DNA binding
0.33	GO:0005125	cytokine activity
0.33	GO:0008376	acetylgalactosaminyltransferase activity
0.33	GO:0005126	cytokine receptor binding

0.36	GO:0031982	vesicle
0.35	GO:0012505	endomembrane system
0.34	GO:0005615	extracellular space
0.34	GO:0043230	extracellular organelle
0.34	GO:0005634	nucleus
0.33	GO:0044444	cytoplasmic part
0.32	GO:0098588	bounding membrane of organelle
0.32	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.40

GO:0016874

sp|Q06453|AL_DROME
Homeobox protein aristaless
Search

0.71	Homeobox protein aristaless

0.62	GO:0007275	multicellular organism development
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.54	GO:0045747	positive regulation of Notch signaling pathway
0.53	GO:0060560	developmental growth involved in morphogenesis
0.51	GO:0002009	morphogenesis of an epithelium
0.48	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process
0.47	GO:0031327	negative regulation of cellular biosynthetic process

0.62	GO:0043565	sequence-specific DNA binding
0.36	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.43	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q06521|VTU3_DROME
Vitelline membrane protein Vm34Ca
Search

0.97	Vitelline membrane protein Vm34Ca

0.85	GO:0007305	vitelline membrane formation involved in chorion-containing eggshell formation
0.61	GO:0007343	egg activation
0.55	GO:0009617	response to bacterium
0.46	GO:0009950	dorsal/ventral axis specification
0.36	GO:0048208	COPII vesicle coating
0.36	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.35	GO:0006914	autophagy
0.34	GO:0015031	protein transport
0.34	GO:0006950	response to stress
0.34	GO:0006468	protein phosphorylation

0.66	GO:0008316	structural constituent of vitelline membrane
0.35	GO:0042302	structural constituent of cuticle
0.35	GO:0005509	calcium ion binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0060388	vitelline envelope
0.52	GO:0005615	extracellular space
0.40	GO:0042600	chorion
0.35	GO:0000139	Golgi membrane
0.35	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|Q06559|RS3_DROME
40S ribosomal protein S3
Search

RPS3

0.57	Ribosomal protein S3

0.60	GO:0006518	peptide metabolic process
0.60	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:0042981	regulation of apoptotic process
0.47	GO:0061481	response to TNF agonist
0.47	GO:1905051	regulation of base-excision repair
0.47	GO:1902546	positive regulation of DNA N-glycosylase activity

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.54	GO:0032357	oxidized purine DNA binding
0.49	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.48	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.47	GO:0032358	oxidized pyrimidine DNA binding
0.46	GO:0097100	supercoiled DNA binding
0.45	GO:0051879	Hsp90 protein binding
0.45	GO:0030544	Hsp70 protein binding
0.45	GO:0044390	ubiquitin-like protein conjugating enzyme binding

0.70	GO:0015935	small ribosomal subunit
0.46	GO:0016363	nuclear matrix
0.45	GO:0071159	NF-kappaB complex
0.45	GO:0022626	cytosolic ribosome
0.44	GO:0032587	ruffle membrane
0.44	GO:0005844	polysome
0.43	GO:0072686	mitotic spindle
0.42	GO:0005730	nucleolus
0.42	GO:0005759	mitochondrial matrix
0.40	GO:0005783	endoplasmic reticulum

0.49

EC:4.2.99.18

GO:0003906

sp|Q06849|ARL2_DROME
ADP-ribosylation factor-like protein 2
Search

ARL2

0.63	ADP-ribosylation factor

0.47	GO:0000226	microtubule cytoskeleton organization
0.47	GO:0045196	establishment or maintenance of neuroblast polarity
0.45	GO:0051653	spindle localization
0.44	GO:0051457	maintenance of protein location in nucleus
0.44	GO:0034260	negative regulation of GTPase activity
0.44	GO:0031116	positive regulation of microtubule polymerization
0.44	GO:0030010	establishment of cell polarity
0.43	GO:0051656	establishment of organelle localization
0.42	GO:1903047	mitotic cell cycle process
0.41	GO:0051649	establishment of localization in cell

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003924	GTPase activity
0.35	GO:0005095	GTPase inhibitor activity
0.34	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.45	GO:0005622	intracellular
0.43	GO:0005925	focal adhesion
0.40	GO:0012505	endomembrane system
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0043228	non-membrane-bounded organelle
0.38	GO:0031975	envelope
0.37	GO:0044422	organelle part
0.37	GO:0043227	membrane-bounded organelle
0.36	GO:0016328	lateral plasma membrane
0.34	GO:0098793	presynapse

0.32

GO:0016491

sp|Q06943|HMGZ_DROME
High mobility group protein Z
Search

0.78	high mobility group protein Z

0.47	GO:0006325	chromatin organization
0.42	GO:0006260	DNA replication
0.41	GO:0006281	DNA repair
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.35	GO:0001672	regulation of chromatin assembly or disassembly
0.34	GO:0030707	ovarian follicle cell development
0.34	GO:0051101	regulation of DNA binding

0.55	GO:0003677	DNA binding
0.35	GO:0070087	chromo shadow domain binding
0.35	GO:0043621	protein self-association
0.34	GO:0031491	nucleosome binding
0.34	GO:0031072	heat shock protein binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0051082	unfolded protein binding
0.33	GO:0070003	threonine-type peptidase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.61	GO:0005634	nucleus
0.50	GO:0005694	chromosome
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.33	GO:0043234	protein complex
0.32	GO:1905369	endopeptidase complex
0.30	GO:0016020	membrane

sp|Q07093|GCYH_DROME
Head-specific guanylate cyclase
Search

0.89	Guanylate cyclase soluble subunit alpha

0.82	GO:0006182	cGMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.54	GO:0046956	positive phototaxis
0.53	GO:0016056	rhodopsin mediated signaling pathway
0.47	GO:0052565	response to defense-related host nitric oxide production
0.46	GO:0060087	relaxation of vascular smooth muscle
0.45	GO:0030828	positive regulation of cGMP biosynthetic process
0.44	GO:0008217	regulation of blood pressure
0.36	GO:0007601	visual perception
0.34	GO:0090594	inflammatory response to wounding

0.83	GO:0004383	guanylate cyclase activity
0.60	GO:0020037	heme binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.42	GO:0004016	adenylate cyclase activity
0.34	GO:0047805	cytidylate cyclase activity
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0043168	anion binding
0.33	GO:0008772	[isocitrate dehydrogenase (NADP+)] kinase activity
0.33	GO:0005515	protein binding

0.57	GO:0008074	guanylate cyclase complex, soluble
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.83	EC:4.6.1.2	GO:0004383
0.34	KEGG:R00574	GO:0047805

sp|Q07152|IMDH_DROME
Inosine-5'-monophosphate dehydrogenase
Search

0.54	Inosine-5'-monophosphate dehydrogenase

0.76	GO:0006177	GMP biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.45	GO:0007411	axon guidance
0.40	GO:0006183	GTP biosynthetic process
0.39	GO:0046651	lymphocyte proliferation
0.37	GO:0007623	circadian rhythm
0.34	GO:0071353	cellular response to interleukin-4
0.34	GO:0051289	protein homotetramerization
0.34	GO:0060041	retina development in camera-type eye

0.78	GO:0003938	IMP dehydrogenase activity
0.53	GO:0046872	metal ion binding
0.51	GO:1901265	nucleoside phosphate binding
0.49	GO:0036094	small molecule binding
0.34	GO:0018580	nitronate monooxygenase activity
0.34	GO:0003677	DNA binding

0.47	GO:0005737	cytoplasm
0.43	GO:0005634	nucleus

0.78

EC:1.1.1.205

GO:0003938

sp|Q07171|GELS_DROME
Gelsolin
Search

0.64	Villin protein quail

0.50	GO:0051014	actin filament severing
0.50	GO:0051016	barbed-end actin filament capping
0.48	GO:0045010	actin nucleation
0.36	GO:0030041	actin filament polymerization
0.34	GO:0007041	lysosomal transport

0.78	GO:0051015	actin filament binding
0.45	GO:0005509	calcium ion binding
0.34	GO:0051219	phosphoprotein binding
0.33	GO:0004872	receptor activity

0.54	GO:0005884	actin filament
0.47	GO:0005829	cytosol
0.46	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q07327|ROP_DROME
Protein ROP
Search

0.71	Syntaxin-binding protein 1

0.80	GO:0006904	vesicle docking involved in exocytosis
0.47	GO:0007269	neurotransmitter secretion
0.46	GO:0007317	regulation of pole plasm oskar mRNA localization
0.45	GO:1900006	positive regulation of dendrite development
0.45	GO:0048468	cell development
0.44	GO:0002065	columnar/cuboidal epithelial cell differentiation
0.43	GO:0000281	mitotic cytokinesis
0.43	GO:0007292	female gamete generation
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.43	GO:0032229	negative regulation of synaptic transmission, GABAergic

0.41	GO:0017075	syntaxin-1 binding
0.35	GO:0043274	phospholipase binding
0.34	GO:0047485	protein N-terminus binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0004055	argininosuccinate synthase activity
0.34	GO:0042802	identical protein binding
0.33	GO:0022857	transmembrane transporter activity
0.32	GO:0003723	RNA binding
0.32	GO:0030554	adenyl nucleotide binding

0.46	GO:0030424	axon
0.46	GO:0098793	presynapse
0.45	GO:0044306	neuron projection terminus
0.43	GO:0005829	cytosol
0.42	GO:0019898	extrinsic component of membrane
0.41	GO:0031091	platelet alpha granule
0.40	GO:0045335	phagocytic vesicle
0.40	GO:0043209	myelin sheath
0.40	GO:0097060	synaptic membrane
0.38	GO:0005654	nucleoplasm

0.34

EC:6.3.4.5

GO:0004055

sp|Q07407|FGFR1_DROME
Fibroblast growth factor receptor homolog 1
Search

0.44	Fibroblast growth factor receptor

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0008543	fibroblast growth factor receptor signaling pathway
0.69	GO:0008284	positive regulation of cell proliferation
0.56	GO:0008347	glial cell migration
0.54	GO:0007500	mesodermal cell fate determination
0.54	GO:0090130	tissue migration
0.54	GO:0007493	endodermal cell fate determination
0.54	GO:0061320	pericardial nephrocyte differentiation
0.54	GO:0007506	gonadal mesoderm development
0.53	GO:0007523	larval visceral muscle development

0.77	GO:0004713	protein tyrosine kinase activity
0.71	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0003677	DNA binding

0.46	GO:0035230	cytoneme
0.37	GO:0005886	plasma membrane
0.35	GO:0005777	peroxisome
0.35	GO:0005634	nucleus
0.33	GO:0098562	cytoplasmic side of membrane
0.33	GO:0019898	extrinsic component of membrane
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

sp|Q07436|EXPA_DROME
Protein expanded
Search

0.96	Putative membrane-associated protein tyrosine phosphatase ptp-bas (Fragment)

0.71	GO:0045571	negative regulation of imaginal disc growth
0.69	GO:0035331	negative regulation of hippo signaling
0.69	GO:0008101	decapentaplegic signaling pathway
0.66	GO:0007298	border follicle cell migration
0.66	GO:0001751	compound eye photoreceptor cell differentiation
0.65	GO:0035329	hippo signaling
0.65	GO:0032456	endocytic recycling
0.64	GO:0007096	regulation of exit from mitosis
0.64	GO:0007050	cell cycle arrest
0.61	GO:0008285	negative regulation of cell proliferation

0.42	GO:0017124	SH3 domain binding
0.32	GO:0003735	structural constituent of ribosome

0.71	GO:0036375	Kibra-Ex-Mer complex
0.69	GO:0005856	cytoskeleton
0.63	GO:0016324	apical plasma membrane
0.45	GO:0005915	zonula adherens
0.32	GO:0005840	ribosome

sp|Q07553|GCY3E_DROME
Guanylate cyclase 32E
Search

0.46	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.46	GO:0045792	negative regulation of cell size
0.44	GO:0007030	Golgi organization
0.44	GO:0045931	positive regulation of mitotic cell cycle
0.43	GO:0008284	positive regulation of cell proliferation
0.37	GO:0007020	microtubule nucleation
0.35	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004016	adenylate cyclase activity
0.38	GO:0004872	receptor activity
0.37	GO:0043015	gamma-tubulin binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding

0.46	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005887	integral component of plasma membrane
0.37	GO:0000922	spindle pole
0.37	GO:0005815	microtubule organizing center
0.33	GO:0043204	perikaryon
0.33	GO:0097730	non-motile cilium
0.33	GO:0030425	dendrite

0.82

EC:4.6.1.2

GO:0004383

sp|Q07886|DDX49_DROME
Probable ATP-dependent RNA helicase Dbp45A
Search

0.49	P-loop containing nucleosidetriphosphatehydrolases

0.42	GO:0010501	RNA secondary structure unwinding
0.38	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.38	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.38	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.37	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0015698	inorganic anion transport
0.33	GO:1902626	assembly of large subunit precursor of preribosome
0.33	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.32	GO:0006303	double-strand break repair via nonhomologous end joining

0.66	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0008186	RNA-dependent ATPase activity
0.38	GO:0140098	catalytic activity, acting on RNA
0.35	GO:0005452	inorganic anion exchanger activity
0.32	GO:0042802	identical protein binding

0.42	GO:0005730	nucleolus
0.34	GO:0005737	cytoplasm
0.33	GO:0030687	preribosome, large subunit precursor
0.30	GO:0031224	intrinsic component of membrane

sp|Q07892|ECLH_DROME
Eclosion hormone
Search

0.97	Eclosion hormone

0.86	GO:0018990	ecdysis, chitin-based cuticle
0.80	GO:0007218	neuropeptide signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.42	GO:0007562	eclosion
0.42	GO:0007563	regulation of eclosion

0.87	GO:0008255	ecdysis-triggering hormone activity
0.43	GO:0008031	eclosion hormone activity

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q07DP5|Q07DP5_DROME
TATA box binding protein-related factor 2, isoform E
Search

TRF2

0.92	TATA box binding protein-related factor 2, isoform E

0.69	GO:0006352	DNA-templated transcription, initiation
0.55	GO:0035209	pupal development
0.55	GO:0035277	spiracle morphogenesis, open tracheal system
0.55	GO:0035071	salivary gland cell autophagic cell death
0.55	GO:0060963	positive regulation of ribosomal protein gene transcription by RNA polymerase II
0.54	GO:0035075	response to ecdysone
0.49	GO:0065004	protein-DNA complex assembly
0.49	GO:0006366	transcription by RNA polymerase II
0.34	GO:0006413	translational initiation
0.33	GO:0055114	oxidation-reduction process

0.55	GO:0003677	DNA binding
0.54	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.49	GO:0003682	chromatin binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0004871	signal transducer activity

0.55	GO:0001674	female germ cell nucleus
0.54	GO:0001673	male germ cell nucleus
0.52	GO:0005700	polytene chromosome
0.50	GO:0005669	transcription factor TFIID complex
0.30	GO:0016020	membrane

0.36

GO:0032440

sp|Q08012|DRK_DROME
Protein enhancer of sevenless 2B
Search

0.96	Downstream of receptor kinase

0.82	GO:0007265	Ras protein signal transduction
0.51	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.50	GO:0002009	morphogenesis of an epithelium
0.50	GO:0009792	embryo development ending in birth or egg hatching
0.50	GO:0043408	regulation of MAPK cascade
0.50	GO:0003006	developmental process involved in reproduction
0.49	GO:0009967	positive regulation of signal transduction
0.49	GO:0045678	positive regulation of R7 cell differentiation
0.49	GO:0007465	R7 cell fate commitment
0.48	GO:0008355	olfactory learning

0.53	GO:0005070	SH3/SH2 adaptor activity
0.49	GO:0005102	receptor binding
0.48	GO:0043560	insulin receptor substrate binding
0.47	GO:0001784	phosphotyrosine residue binding
0.46	GO:0019903	protein phosphatase binding
0.45	GO:0017124	SH3 domain binding
0.44	GO:0019901	protein kinase binding
0.43	GO:0042802	identical protein binding
0.42	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.34	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.49	GO:0070436	Grb2-EGFR complex
0.45	GO:0008180	COP9 signalosome
0.44	GO:0005911	cell-cell junction
0.44	GO:0012506	vesicle membrane
0.43	GO:0005768	endosome
0.43	GO:0005730	nucleolus
0.42	GO:0005654	nucleoplasm
0.42	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0005794	Golgi apparatus
0.35	GO:0070062	extracellular exosome

0.42	EC:2.7.10.2	GO:0004715
0.34	KEGG:R04545	GO:0046934

sp|Q08180|ICCR_DROME
Irregular chiasm C-roughest protein
Search

0.82	Cell adhesion molecule RST

0.58	GO:0001745	compound eye morphogenesis
0.58	GO:0016202	regulation of striated muscle tissue development
0.55	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.48	GO:0061321	garland nephrocyte differentiation
0.48	GO:0036059	nephrocyte diaphragm assembly
0.48	GO:0097206	nephrocyte filtration
0.47	GO:0007523	larval visceral muscle development
0.47	GO:0007520	myoblast fusion
0.46	GO:1901739	regulation of myoblast fusion
0.46	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

0.54	GO:0030165	PDZ domain binding
0.49	GO:0042802	identical protein binding
0.44	GO:0050839	cell adhesion molecule binding

0.56	GO:0005912	adherens junction
0.54	GO:0005911	cell-cell junction
0.53	GO:0016324	apical plasma membrane
0.43	GO:0009986	cell surface
0.41	GO:0030176	integral component of endoplasmic reticulum membrane

sp|Q08473|SQD_DROME
RNA-binding protein squid
Search

SQD

0.78	RNA-binding protein musashi

0.49	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.49	GO:0030720	oocyte localization involved in germarium-derived egg chamber formation
0.48	GO:0045451	pole plasm oskar mRNA localization
0.48	GO:0016325	oocyte microtubule cytoskeleton organization
0.48	GO:0033119	negative regulation of RNA splicing
0.47	GO:0007297	ovarian follicle cell migration
0.36	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0017148	negative regulation of translation

0.59

GO:0003723

RNA binding

0.49	GO:0035062	omega speckle
0.48	GO:0005703	polytene chromosome puff
0.43	GO:0000785	chromatin
0.39	GO:0019013	viral nucleocapsid
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0005730	nucleolus
0.34	GO:1902494	catalytic complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q08605|GAGA_DROME
Transcription factor GAGA
Search

TRL

0.97	Transcription factor GAGA

0.39	GO:0035186	syncytial blastoderm mitotic cell cycle
0.39	GO:1990000	amyloid fibril formation
0.39	GO:0031937	positive regulation of chromatin silencing
0.39	GO:0007549	dosage compensation
0.39	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.39	GO:0035075	response to ecdysone
0.38	GO:0007476	imaginal disc-derived wing morphogenesis
0.38	GO:0043044	ATP-dependent chromatin remodeling
0.38	GO:0048477	oogenesis
0.38	GO:0007283	spermatogenesis

0.51	GO:0003676	nucleic acid binding
0.40	GO:0031208	POZ domain binding
0.37	GO:0003682	chromatin binding
0.37	GO:0046982	protein heterodimerization activity
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0008134	transcription factor binding
0.36	GO:0008270	zinc ion binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004622	lysophospholipase activity
0.34	GO:0004672	protein kinase activity

0.38	GO:0005721	pericentric heterochromatin
0.38	GO:0000791	euchromatin
0.38	GO:0005700	polytene chromosome
0.36	GO:0005634	nucleus
0.33	GO:0031248	protein acetyltransferase complex
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005667	transcription factor complex
0.33	GO:1905368	peptidase complex
0.32	GO:0016459	myosin complex

0.35

EC:3.1.1.5

GO:0004622

sp|Q08694|LYSB_DROME
Lysozyme B
Search

0.53	Lysozyme B

0.43	GO:0050830	defense response to Gram-positive bacterium
0.43	GO:0050829	defense response to Gram-negative bacterium
0.41	GO:0016998	cell wall macromolecule catabolic process
0.41	GO:0019835	cytolysis
0.34	GO:0045824	negative regulation of innate immune response

0.77	GO:0003796	lysozyme activity
0.35	GO:0004568	chitinase activity

0.40	GO:0005615	extracellular space
0.33	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0003796

sp|Q08832|GBRB3_DROME
Gamma-aminobutyric acid receptor subunit beta-like
Search

0.87	Gamma-aminobutyric acid receptor subunit beta

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.46	GO:0006821	chloride transport
0.34	GO:0007268	chemical synaptic transmission
0.32	GO:0055114	oxidation-reduction process

0.83	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.47	GO:0099095	ligand-gated anion channel activity
0.45	GO:0005254	chloride channel activity
0.44	GO:0022835	transmitter-gated channel activity
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.33	GO:0005507	copper ion binding

0.55	GO:0005886	plasma membrane
0.42	GO:1902711	GABA-A receptor complex
0.38	GO:0034707	chloride channel complex
0.37	GO:0098794	postsynapse
0.37	GO:0030054	cell junction

0.34

EC:1.14.17

GO:0016715

sp|Q09024|IMPL2_DROME
Neural/ectodermal development factor IMP-L2
Search

IMPL2

0.85	Neural/ectodermal development factor IMP-L2

0.86	GO:0046628	positive regulation of insulin receptor signaling pathway
0.86	GO:0010888	negative regulation of lipid storage
0.85	GO:0046627	negative regulation of insulin receptor signaling pathway
0.84	GO:0008340	determination of adult lifespan
0.42	GO:0007155	cell adhesion

0.83

GO:0005520

insulin-like growth factor binding

0.72	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|Q09101|HIG_DROME
Locomotion-related protein Hikaru genki
Search

HIG

0.79	Locomotion-related protein Hikaru genki

0.84	GO:0008039	synaptic target recognition
0.45	GO:0007155	cell adhesion
0.37	GO:0010466	negative regulation of peptidase activity

0.41	GO:0030246	carbohydrate binding
0.41	GO:0005515	protein binding
0.38	GO:0005509	calcium ion binding
0.37	GO:0030414	peptidase inhibitor activity
0.35	GO:0003682	chromatin binding

0.83	GO:0043083	synaptic cleft
0.76	GO:0043025	neuronal cell body
0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q09103|DGK2_DROME
Eye-specific diacylglycerol kinase
Search

0.40	Eye-specific diacylglycerol kinase

0.82	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.60	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.38	GO:0016059	deactivation of rhodopsin mediated signaling
0.37	GO:0043052	thermotaxis
0.37	GO:0016056	rhodopsin mediated signaling pathway
0.37	GO:0045494	photoreceptor cell maintenance
0.36	GO:0007605	sensory perception of sound
0.36	GO:0006654	phosphatidic acid biosynthetic process
0.36	GO:0007601	visual perception

0.79	GO:0004143	diacylglycerol kinase activity
0.74	GO:0003951	NAD+ kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.44	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.79	EC:2.7.1.107	GO:0004143
0.74	KEGG:R00104	GO:0003951

sp|Q09147|FGFR2_DROME
Fibroblast growth factor receptor homolog 2
Search

0.37	Fibroblast growth factor receptor

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.68	GO:0008543	fibroblast growth factor receptor signaling pathway
0.64	GO:0008284	positive regulation of cell proliferation
0.58	GO:0007429	secondary branching, open tracheal system
0.58	GO:0008347	glial cell migration
0.57	GO:0007428	primary branching, open tracheal system
0.57	GO:0035153	epithelial cell type specification, open tracheal system
0.56	GO:0090130	tissue migration
0.56	GO:0007430	terminal branching, open tracheal system
0.56	GO:0007426	tracheal outgrowth, open tracheal system

0.77	GO:0004713	protein tyrosine kinase activity
0.68	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0017134	fibroblast growth factor binding
0.33	GO:1901681	sulfur compound binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.57	GO:0035230	cytoneme
0.41	GO:0005886	plasma membrane
0.36	GO:0005777	peroxisome
0.33	GO:0030133	transport vesicle
0.33	GO:0005911	cell-cell junction
0.33	GO:0005634	nucleus
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

sp|Q09332|UGGG_DROME
UDP-glucose:glycoprotein glucosyltransferase
Search

0.72	UDP-glucose glycoprotein glucosyltransferase 2

0.85	GO:0097359	UDP-glucosylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.42	GO:0071218	cellular response to misfolded protein
0.42	GO:0030968	endoplasmic reticulum unfolded protein response
0.42	GO:0051084	'de novo' posttranslational protein folding
0.41	GO:0010243	response to organonitrogen compound
0.39	GO:0030163	protein catabolic process

0.85	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity
0.39	GO:0051082	unfolded protein binding
0.35	GO:0008324	cation transmembrane transporter activity
0.32	GO:0016301	kinase activity

0.48	GO:0005791	rough endoplasmic reticulum
0.46	GO:0005635	nuclear envelope
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.85

GO:0003980

sp|Q0E8C8|SP77B_DROME
Serine protease inhibitor 77Ba
Search

0.50	Serine protease inhibitor

0.70	GO:0035009	negative regulation of melanization defense response
0.43	GO:0042438	melanin biosynthetic process
0.42	GO:0010951	negative regulation of endopeptidase activity
0.38	GO:0035490	regulation of leukotriene production involved in inflammatory response
0.38	GO:1901331	positive regulation of odontoblast differentiation
0.38	GO:0061044	negative regulation of vascular wound healing
0.38	GO:0097187	dentinogenesis
0.38	GO:2000098	negative regulation of smooth muscle cell-matrix adhesion
0.37	GO:0010757	negative regulation of plasminogen activation
0.37	GO:0033629	negative regulation of cell adhesion mediated by integrin

0.42	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0008233	peptidase activity
0.37	GO:0002020	protease binding
0.35	GO:0005102	receptor binding

0.73	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.37

GO:0008233

tr|Q0E8D0|Q0E8D0_DROME
IP21319p
Search

0.55

GO:0003677

DNA binding

tr|Q0E8E1|Q0E8E1_DROME
GH08173p
Search

0.36	proton-coupled folate transporter

0.54	GO:0055085	transmembrane transport
0.39	GO:0009190	cyclic nucleotide biosynthetic process
0.39	GO:0046058	cAMP metabolic process
0.37	GO:0009152	purine ribonucleotide biosynthetic process
0.33	GO:0035556	intracellular signal transduction

0.39	GO:0004016	adenylate cyclase activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding
0.31	GO:0005215	transporter activity

0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:4.6.1.1

GO:0004016

tr|Q0E8E2|Q0E8E2_DROME
CG4998, isoform B
Search

0.10	Serine proteinase stubble

0.60	GO:0006508	proteolysis
0.34	GO:0007017	microtubule-based process
0.34	GO:0007010	cytoskeleton organization

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

tr|Q0E8E7|Q0E8E7_DROME
tRNA-splicing endonuclease subunit Sen34
Search

0.62	tRNA-splicing endonuclease subunit Sen34

0.85	GO:0000379	tRNA-type intron splice site recognition and cleavage
0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006397	mRNA processing
0.33	GO:0042147	retrograde transport, endosome to Golgi
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.83	GO:0000213	tRNA-intron endonuclease activity
0.59	GO:0016829	lyase activity
0.51	GO:0003676	nucleic acid binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding

0.83	GO:0000214	tRNA-intron endonuclease complex
0.34	GO:0005730	nucleolus
0.33	GO:0015935	small ribosomal subunit
0.33	GO:0005654	nucleoplasm
0.32	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:3.1.27.9

GO:0000213

tr|Q0E8E8|Q0E8E8_DROME
MIP08013p1
Search

0.40	phosphate carrier protein, mitochondrial

0.48	GO:0048190	wing disc dorsal/ventral pattern formation
0.41	GO:0006506	GPI anchor biosynthetic process
0.41	GO:0035435	phosphate ion transmembrane transport
0.40	GO:0006839	mitochondrial transport
0.34	GO:1902358	sulfate transmembrane transport

0.43	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.41	GO:0015114	phosphate ion transmembrane transporter activity
0.34	GO:0008271	secondary active sulfate transmembrane transporter activity

0.37	GO:0005740	mitochondrial envelope
0.37	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.43

EC:2.4.1.198

GO:0017176

tr|Q0E8F2|Q0E8F2_DROME
FI05451p
Search

0.63	Calcium-binding mitochondrial carrier protein SCaMC-2

0.55	GO:0055085	transmembrane transport
0.42	GO:0015866	ADP transport
0.42	GO:0015867	ATP transport
0.40	GO:0006839	mitochondrial transport
0.36	GO:0032094	response to food
0.36	GO:0002021	response to dietary excess
0.36	GO:0014823	response to activity
0.36	GO:0060612	adipose tissue development
0.36	GO:0035264	multicellular organism growth
0.35	GO:0043010	camera-type eye development

0.62	GO:0005509	calcium ion binding
0.42	GO:0015217	ADP transmembrane transporter activity
0.42	GO:0005347	ATP transmembrane transporter activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.55	GO:0031966	mitochondrial membrane
0.55	GO:0019866	organelle inner membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0032440

tr|Q0E8G6|Q0E8G6_DROME
CG3689, isoform C
Search

0.71	Cleavage and polyadenylation specificity factor subunit

0.81	GO:0006378	mRNA polyadenylation
0.42	GO:0031439	positive regulation of mRNA cleavage
0.41	GO:1900365	positive regulation of mRNA polyadenylation
0.40	GO:0051290	protein heterotetramerization
0.40	GO:0098789	pre-mRNA cleavage required for polyadenylation
0.38	GO:1901800	positive regulation of proteasomal protein catabolic process
0.36	GO:0030163	protein catabolic process
0.35	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.35	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.76	GO:0003729	mRNA binding
0.51	GO:0016787	hydrolase activity
0.40	GO:0017091	AU-rich element binding
0.39	GO:0042826	histone deacetylase binding
0.38	GO:0003682	chromatin binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0043021	ribonucleoprotein complex binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding

0.81	GO:0005849	mRNA cleavage factor complex
0.41	GO:0042382	paraspeckles
0.38	GO:0005813	centrosome
0.35	GO:0030687	preribosome, large subunit precursor
0.35	GO:0005737	cytoplasm
0.34	GO:0036038	MKS complex
0.34	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016787

tr|Q0E8H7|Q0E8H7_DROME
FI19426p1
Search

0.53	Major facilitator superfamily domain-containing protein 6-A

0.33	GO:0016539	intein-mediated protein splicing
0.32	GO:0007267	cell-cell signaling
0.32	GO:0007275	multicellular organism development
0.31	GO:0006468	protein phosphorylation

0.32	GO:0008270	zinc ion binding
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0016787	hydrolase activity
0.31	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.31	GO:0016301	kinase activity

0.30

GO:0031224

intrinsic component of membrane

0.32

GO:0016787

tr|Q0E8H8|Q0E8H8_DROME
BG642312, isoform A
Search

0.13	Male accessory gland protein

0.85	GO:0048042	regulation of post-mating oviposition
0.48	GO:0032504	multicellular organism reproduction

0.46	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|Q0E8H9|Q0E8H9_DROME
Hexosaminidase 1, isoform A
Search

0.46	Chitooligosaccharidolytic beta-N-acetylglucosaminidase

0.60	GO:0005975	carbohydrate metabolic process
0.54	GO:0016063	rhodopsin biosynthetic process
0.52	GO:0006517	protein deglycosylation
0.51	GO:0006491	N-glycan processing
0.37	GO:0006367	transcription initiation from RNA polymerase II promoter
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0006032	chitin catabolic process
0.34	GO:0046854	phosphatidylinositol phosphorylation

0.79	GO:0004563	beta-N-acetylhexosaminidase activity
0.74	GO:0102148	N-acetyl-beta-D-galactosaminidase activity
0.34	GO:0016307	phosphatidylinositol phosphate kinase activity
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0003677	DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005886	plasma membrane
0.35	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.79

EC:3.2.1.52

GO:0004563

tr|Q0E8J0|Q0E8J0_DROME
MEP-1, isoform A
Search

0.81	MOG interacting and ectopic P-granules protein 1

0.53

GO:0000122

negative regulation of transcription by RNA polymerase II

0.59	GO:0070615	nucleosome-dependent ATPase activity
0.53	GO:0003682	chromatin binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding

0.57	GO:0090545	CHD-type complex
0.56	GO:0005700	polytene chromosome
0.56	GO:0090568	nuclear transcriptional repressor complex
0.55	GO:0000118	histone deacetylase complex

tr|Q0E8K5|Q0E8K5_DROME
AT10158p
Search

0.52	BTB/POZ domain-containing protein 10

0.80	GO:0050975	sensory perception of touch
0.47	GO:0043413	macromolecule glycosylation
0.47	GO:0009101	glycoprotein biosynthetic process
0.41	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0006313	transposition, DNA-mediated
0.37	GO:0065009	regulation of molecular function

0.50	GO:0004576	oligosaccharyl transferase activity
0.50	GO:0004370	glycerol kinase activity
0.39	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0004803	transposase activity
0.35	GO:0003677	DNA binding

0.30

GO:0016020

membrane

0.50	EC:2.4.1	GO:0004576
0.50	KEGG:R00847	GO:0004370

tr|Q0E8K6|Q0E8K6_DROME
tRNA pseudouridine synthase
Search

0.50	tRNA pseudouridine synthase

0.72	GO:0001522	pseudouridine synthesis
0.64	GO:0008033	tRNA processing
0.52	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0006468	protein phosphorylation
0.34	GO:0001510	RNA methylation

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding
0.54	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.52	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0031515	tRNA (m1A) methyltransferase complex
0.33	GO:0043231	intracellular membrane-bounded organelle

0.72

EC:5.4.99.12

GO:0009982

tr|Q0E8K8|Q0E8K8_DROME
FI21816p1
Search

0.62	arrestin domain-containing protein 4

0.61	GO:0007165	signal transduction
0.44	GO:0010629	negative regulation of gene expression
0.33	GO:0006486	protein glycosylation

0.33	GO:0030246	carbohydrate binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016757

tr|Q0E8L1|Q0E8L1_DROME
Uncharacterized protein
Search

tr|Q0E8M3|Q0E8M3_DROME
MIP14022p
Search

tr|Q0E8N2|Q0E8N2_DROME
MIP16918p
Search

0.92	Putative pattern-formation protein/guanine nucleotide exchange factor

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.47	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.47	GO:0040018	positive regulation of multicellular organism growth
0.47	GO:0001700	embryonic development via the syncytial blastoderm
0.46	GO:0030100	regulation of endocytosis
0.45	GO:0110020	regulation of actomyosin structure organization
0.45	GO:0016331	morphogenesis of embryonic epithelium
0.45	GO:0043410	positive regulation of MAPK cascade
0.38	GO:0046579	positive regulation of Ras protein signal transduction

0.81	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.47	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.43	GO:0042803	protein homodimerization activity
0.35	GO:0034450	ubiquitin-ubiquitin ligase activity
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0008061	chitin binding
0.33	GO:0016791	phosphatase activity
0.33	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.49	GO:1904269	cell leading edge cell cortex
0.46	GO:0032154	cleavage furrow
0.46	GO:0070938	contractile ring
0.45	GO:0005913	cell-cell adherens junction
0.38	GO:0005886	plasma membrane
0.36	GO:0000139	Golgi membrane
0.36	GO:0005829	cytosol
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0000151	ubiquitin ligase complex
0.33	GO:0005576	extracellular region

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|Q0E8N3|Q0E8N3_DROME
No long nerve cord, isoform C
Search

0.10	No long nerve cord, isoform C

0.60	GO:0007229	integrin-mediated signaling pathway
0.54	GO:0006508	proteolysis
0.46	GO:0007419	ventral cord development
0.34	GO:0006814	sodium ion transport
0.34	GO:0006813	potassium ion transport

0.55

GO:0008233

peptidase activity

0.36

GO:0005890

sodium:potassium-exchanging ATPase complex

0.55

GO:0008233

tr|Q0E8N6|Q0E8N6_DROME
Clumsy, isoform B
Search

0.64	Ionotropic glutamate receptor

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.47	GO:0007274	neuromuscular synaptic transmission
0.47	GO:0060025	regulation of synaptic activity
0.46	GO:0030510	regulation of BMP signaling pathway
0.46	GO:0019722	calcium-mediated signaling
0.44	GO:0006816	calcium ion transport
0.43	GO:0035249	synaptic transmission, glutamatergic
0.43	GO:0060074	synapse maturation

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.48	GO:0099094	ligand-gated cation channel activity
0.45	GO:0005262	calcium channel activity
0.41	GO:0005272	sodium channel activity
0.40	GO:0098782	mechanosensitived potassium channel activity

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.49	GO:0097482	muscle cell postsynaptic specialization
0.47	GO:0008328	ionotropic glutamate receptor complex
0.35	GO:0005622	intracellular

tr|Q0E8P0|Q0E8P0_DROME
(6-4)-photolyase, isoform A
Search

0.57	Cryptochrome circadian clock 5

0.55	GO:0009416	response to light stimulus
0.47	GO:0006950	response to stress
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0009649	entrainment of circadian clock
0.44	GO:0051716	cellular response to stimulus
0.44	GO:0006259	DNA metabolic process
0.41	GO:0048511	rhythmic process
0.41	GO:1901700	response to oxygen-containing compound
0.40	GO:0010035	response to inorganic substance
0.39	GO:0042493	response to drug

0.60	GO:0003914	DNA (6-4) photolyase activity
0.39	GO:0009881	photoreceptor activity
0.37	GO:0005515	protein binding
0.37	GO:0001046	core promoter sequence-specific DNA binding
0.37	GO:1901265	nucleoside phosphate binding
0.36	GO:0036094	small molecule binding
0.36	GO:0000989	transcription factor activity, transcription factor binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0008144	drug binding
0.33	GO:0097367	carbohydrate derivative binding

0.50	GO:0097381	photoreceptor disc membrane
0.50	GO:0042622	photoreceptor outer segment membrane
0.43	GO:0005829	cytosol
0.43	GO:0005667	transcription factor complex
0.42	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion

0.60

EC:4.1.99.13

GO:0003914

tr|Q0E8P5|Q0E8P5_DROME
CG5758, isoform A
Search

0.38	Transforming growth factor-beta-induced protein ig-h3

0.86	GO:0008039	synaptic target recognition
0.47	GO:0030198	extracellular matrix organization
0.44	GO:0007155	cell adhesion

0.46	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0005615	extracellular space

tr|Q0E8P6|Q0E8P6_DROME
Beethoven
Search

0.54	cytoplasmic dynein 2 heavy chain 1

0.74	GO:0007018	microtubule-based movement
0.59	GO:0045433	male courtship behavior, veined wing generated song production
0.59	GO:0031223	auditory behavior
0.57	GO:0007628	adult walking behavior
0.55	GO:0030705	cytoskeleton-dependent intracellular transport
0.55	GO:0031503	protein complex localization
0.54	GO:0007605	sensory perception of sound
0.54	GO:0044782	cilium organization
0.49	GO:0006886	intracellular protein transport
0.42	GO:0120031	plasma membrane bounded cell projection assembly

0.75	GO:0003777	microtubule motor activity
0.59	GO:0016887	ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0045503	dynein light chain binding
0.44	GO:0051959	dynein light intermediate chain binding
0.44	GO:0045505	dynein intermediate chain binding
0.40	GO:0005509	calcium ion binding

0.75	GO:0030286	dynein complex
0.55	GO:0005930	axoneme
0.36	GO:0005914	spot adherens junction
0.36	GO:0097730	non-motile cilium
0.35	GO:0016342	catenin complex
0.35	GO:0030175	filopodium
0.35	GO:0055037	recycling endosome
0.35	GO:0031514	motile cilium
0.35	GO:0043296	apical junction complex
0.34	GO:0060170	ciliary membrane

0.59

GO:0016887

tr|Q0E8Q6|Q0E8Q6_DROME
Uncharacterized protein, isoform B
Search

0.44

GO:0006357

regulation of transcription by RNA polymerase II

0.54	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.39	GO:0046983	protein dimerization activity

0.41

GO:0005634

nucleus

tr|Q0E8Q7|Q0E8Q7_DROME
Uncharacterized protein, isoform B
Search

0.61	ATP-binding cassette sub-family A member 3

0.55	GO:0055085	transmembrane transport
0.42	GO:0006869	lipid transport
0.40	GO:0032374	regulation of cholesterol transport
0.39	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.39	GO:0034380	high-density lipoprotein particle assembly
0.38	GO:0002040	sprouting angiogenesis
0.37	GO:0097035	regulation of membrane lipid distribution
0.37	GO:0015850	organic hydroxy compound transport
0.37	GO:0015748	organophosphate ester transport
0.36	GO:0042632	cholesterol homeostasis

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0090556	phosphatidylserine-translocating ATPase activity
0.39	GO:0034188	apolipoprotein A-I receptor activity
0.39	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.36	GO:0034186	apolipoprotein A-I binding
0.35	GO:0017127	cholesterol transporter activity

0.37	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0005886	plasma membrane
0.36	GO:0012505	endomembrane system
0.35	GO:0030054	cell junction
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0098857	membrane microdomain
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0034364	high-density lipoprotein particle
0.34	GO:0009986	cell surface
0.34	GO:0098552	side of membrane

0.33

EC:1.4.3.5

GO:0004733

tr|Q0E8R1|Q0E8R1_DROME
FI07211p
Search

0.43

nucleolin

0.78	GO:0051607	defense response to virus
0.33	GO:0034220	ion transmembrane transport

0.33

GO:0005216

ion channel activity

0.30

GO:0016021

integral component of membrane

tr|Q0E8R3|Q0E8R3_DROME
Bruno-2, isoform E
Search

0.63	CUGBP Elav family member 2

0.47	GO:0017148	negative regulation of translation
0.43	GO:0046835	carbohydrate phosphorylation

0.59	GO:0003723	RNA binding
0.44	GO:0004747	ribokinase activity

0.30

GO:0031224

intrinsic component of membrane

0.44

EC:2.7.1.15

GO:0004747

tr|Q0E8S7|Q0E8S7_DROME
Homer, isoform E
Search

0.83	Homer protein like protein 2

0.85	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.83	GO:0048149	behavioral response to ethanol
0.73	GO:0040012	regulation of locomotion
0.43	GO:0018094	protein polyglycylation
0.36	GO:0007229	integrin-mediated signaling pathway
0.34	GO:0006486	protein glycosylation
0.34	GO:0006508	proteolysis
0.34	GO:0006396	RNA processing

0.52	GO:0035256	G-protein coupled glutamate receptor binding
0.45	GO:0008022	protein C-terminus binding
0.45	GO:0070737	protein-glycine ligase activity, elongating
0.44	GO:0070736	protein-glycine ligase activity, initiating
0.43	GO:0042802	identical protein binding
0.43	GO:0019904	protein domain specific binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004222	metalloendopeptidase activity

0.76	GO:0030425	dendrite
0.67	GO:0005783	endoplasmic reticulum
0.45	GO:0045178	basal part of cell
0.45	GO:0014069	postsynaptic density
0.41	GO:0005829	cytosol
0.39	GO:0015630	microtubule cytoskeleton
0.35	GO:0005576	extracellular region
0.34	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:6.3.2

GO:0070737

tr|Q0E8T1|Q0E8T1_DROME
Uncharacterized protein, isoform B
Search

0.45	pancreatic triacylglycerol lipase

0.60	GO:0006629	lipid metabolic process
0.53	GO:0032504	multicellular organism reproduction
0.35	GO:1901575	organic substance catabolic process
0.35	GO:0019637	organophosphate metabolic process
0.34	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0015992	proton transport
0.32	GO:0055085	transmembrane transport

0.70	GO:0052689	carboxylic ester hydrolase activity
0.48	GO:0016298	lipase activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.66	GO:0005576	extracellular region
0.34	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.30	GO:0031224	intrinsic component of membrane

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

tr|Q0E8T4|Q0E8T4_DROME
GH26238p1
Search

0.54

GO:0005201

extracellular matrix structural constituent

0.54	GO:0005604	basement membrane
0.53	GO:0005581	collagen trimer

tr|Q0E8T6|Q0E8T6_DROME
Uncharacterized protein
Search

0.42	Carboxypeptidase D

0.53	GO:0019673	GDP-mannose metabolic process
0.42	GO:0006508	proteolysis

0.54	GO:0008446	GDP-mannose 4,6-dehydratase activity
0.46	GO:0004180	carboxypeptidase activity
0.41	GO:0003723	RNA binding

0.54	EC:4.2.1.47	GO:0008446
0.54	KEGG:R00888	GO:0008446

tr|Q0E8T7|Q0E8T7_DROME
FI23230p1
Search

0.69	cilia- and flagella-associated protein 44

0.67	GO:0060285	cilium-dependent cell motility
0.36	GO:0090307	mitotic spindle assembly
0.35	GO:0090116	C-5 methylation of cytosine
0.35	GO:0000413	protein peptidyl-prolyl isomerization

0.37	GO:0004381	fucosylgalactoside 3-alpha-galactosyltransferase activity
0.36	GO:0008663	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity
0.35	GO:0003886	DNA (cytosine-5-)-methyltransferase activity
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.63	GO:0031514	motile cilium
0.30	GO:0016020	membrane

0.37

EC:2.4.1.37

GO:0004381

tr|Q0E8U2|Q0E8U2_DROME
CG9664, isoform A
Search

0.25	Abc transporter

0.55	GO:0042048	olfactory behavior
0.43	GO:0030301	cholesterol transport
0.34	GO:0055085	transmembrane transport
0.34	GO:0033060	ocellus pigmentation
0.34	GO:0006726	eye pigment biosynthetic process
0.33	GO:0015716	organic phosphonate transport
0.33	GO:0015748	organophosphate ester transport
0.33	GO:0099133	ATP hydrolysis coupled anion transmembrane transport
0.33	GO:0015888	thiamine transport
0.33	GO:0044550	secondary metabolite biosynthetic process

0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0017127	cholesterol transporter activity
0.41	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.39	GO:0015399	primary active transmembrane transporter activity
0.33	GO:0015604	organic phosphonate transmembrane transporter activity
0.33	GO:0015605	organophosphate ester transmembrane transporter activity
0.33	GO:0033897	ribonuclease T2 activity

0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.61

GO:0016887

tr|Q0E8U4|Q0E8U4_DROME
FI09636p
Search

UPP1

0.47	Uridine phosphorylase

0.75	GO:0009166	nucleotide catabolic process
0.66	GO:0009116	nucleoside metabolic process
0.64	GO:0032262	pyrimidine nucleotide salvage
0.59	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process
0.58	GO:0009218	pyrimidine ribonucleotide metabolic process
0.56	GO:1901659	glycosyl compound biosynthetic process
0.54	GO:0009260	ribonucleotide biosynthetic process
0.43	GO:0072529	pyrimidine-containing compound catabolic process
0.43	GO:0042332	gravitaxis
0.43	GO:1901658	glycosyl compound catabolic process

0.82	GO:0004850	uridine phosphorylase activity
0.33	GO:0015299	solute:proton antiporter activity

0.49	GO:0005737	cytoplasm
0.41	GO:0005654	nucleoplasm
0.34	GO:0045098	type III intermediate filament
0.30	GO:0016020	membrane

0.82

EC:2.4.2.3

GO:0004850

tr|Q0E8U8|Q0E8U8_DROME
Uncharacterized protein, isoform B
Search

0.47	GO:0032793	positive regulation of CREB transcription factor activity
0.46	GO:0051289	protein homotetramerization
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0042594	response to starvation
0.41	GO:1902476	chloride transmembrane transport
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:0006979	response to oxidative stress
0.39	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0002009	morphogenesis of an epithelium
0.38	GO:0007424	open tracheal system development

0.47	GO:0008140	cAMP response element binding protein binding
0.43	GO:0003676	nucleic acid binding
0.43	GO:0008270	zinc ion binding
0.41	GO:0005254	chloride channel activity
0.40	GO:0001104	RNA polymerase II transcription cofactor activity
0.39	GO:0004930	G-protein coupled receptor activity
0.38	GO:0016301	kinase activity
0.38	GO:0003700	DNA binding transcription factor activity
0.38	GO:0050825	ice binding
0.37	GO:0046983	protein dimerization activity

0.48	GO:0005634	nucleus
0.42	GO:0034707	chloride channel complex
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0043234	protein complex
0.38	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.37	GO:0005886	plasma membrane
0.36	GO:0005927	muscle tendon junction
0.36	GO:0015629	actin cytoskeleton
0.35	GO:0045177	apical part of cell

0.37

GO:0016773

tr|Q0E8V6|Q0E8V6_DROME
Serpin 28Da
Search

0.10	Serine protease inhibitor (Serpin-3)

0.50	GO:0032504	multicellular organism reproduction
0.44	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0050829	defense response to Gram-negative bacterium
0.38	GO:0006508	proteolysis

0.44	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.38

GO:0008233

tr|Q0E8V7|Q0E8V7_DROME
GEO11073p1
Search

0.83	Mitochondrial import inner membrane translocase subunit 13

0.65	GO:0015031	protein transport
0.46	GO:0090151	establishment of protein localization to mitochondrial membrane
0.46	GO:0007007	inner mitochondrial membrane organization
0.45	GO:1990542	mitochondrial transmembrane transport
0.42	GO:0046907	intracellular transport
0.34	GO:0007605	sensory perception of sound
0.34	GO:1990884	RNA acetylation
0.33	GO:0042274	ribosomal small subunit biogenesis
0.33	GO:0000154	rRNA modification
0.33	GO:0006400	tRNA modification

0.54	GO:0046872	metal ion binding
0.42	GO:0008565	protein transporter activity
0.34	GO:1904680	peptide transmembrane transporter activity
0.33	GO:0022884	macromolecule transmembrane transporter activity
0.33	GO:0015399	primary active transmembrane transporter activity
0.33	GO:0008080	N-acetyltransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005739	mitochondrion
0.46	GO:0001650	fibrillar center
0.44	GO:0031970	organelle envelope lumen
0.41	GO:1990351	transporter complex
0.40	GO:0019866	organelle inner membrane
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008080

tr|Q0E8V8|Q0E8V8_DROME
CG9380, isoform G
Search

0.11	N-acetylmuramoyl-L-alanine amidase

0.63	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.36	GO:0017134	fibroblast growth factor binding
0.34	GO:0003676	nucleic acid binding

0.30

GO:0044425

membrane part

0.63

EC:3.5.1.28

GO:0008745

tr|Q0E8W5|Q0E8W5_DROME
Ion transport peptide, isoform C
Search

0.92	Ion Transport Peptide like

0.75	GO:0010469	regulation of receptor activity
0.57	GO:0042745	circadian sleep/wake cycle
0.56	GO:0045475	locomotor rhythm
0.52	GO:0007218	neuropeptide signaling pathway

0.84	GO:0005184	neuropeptide hormone activity
0.34	GO:0003924	GTPase activity
0.33	GO:0001883	purine nucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032549	ribonucleoside binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|Q0E8W6|Q0E8W6_DROME
IP15630p
Search

0.45	small integral membrane protein 14

0.30

GO:0044425

membrane part

tr|Q0E8W8|Q0E8W8_DROME
CG3494, isoform A
Search

0.51	leucine-rich repeat-containing protein 40

0.42	GO:0007165	signal transduction
0.41	GO:0006468	protein phosphorylation
0.41	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0065009	regulation of molecular function
0.34	GO:0055114	oxidation-reduction process

0.41	GO:0004672	protein kinase activity
0.41	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.39	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0030246	carbohydrate binding

0.38	GO:0005886	plasma membrane
0.34	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.39

GO:0032440

tr|Q0E8X7|Q0E8X7_DROME
Uncharacterized protein, isoform A
Search

0.11	Putative conserved plasma membrane protein (Fragment)

0.59

GO:0016063

rhodopsin biosynthetic process

0.30

GO:0031224

intrinsic component of membrane

tr|Q0E8X8|Q0E8X8_DROME
FI01416p
Search

0.82	Mitochondrial ATPase inhibitor IATP

0.81	GO:0032780	negative regulation of ATPase activity
0.49	GO:0050830	defense response to Gram-positive bacterium
0.39	GO:0006783	heme biosynthetic process
0.38	GO:0035999	tetrahydrofolate interconversion
0.38	GO:0009396	folic acid-containing compound biosynthetic process
0.36	GO:0007275	multicellular organism development
0.36	GO:0034101	erythrocyte homeostasis
0.36	GO:0051882	mitochondrial depolarization
0.35	GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
0.35	GO:0001937	negative regulation of endothelial cell proliferation

0.82	GO:0042030	ATPase inhibitor activity
0.41	GO:0051117	ATPase binding
0.40	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity
0.38	GO:0004386	helicase activity
0.36	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008144	drug binding
0.35	GO:0043532	angiostatin binding
0.35	GO:0003676	nucleic acid binding

0.61	GO:0005739	mitochondrion
0.34	GO:0009986	cell surface
0.33	GO:0045259	proton-transporting ATP synthase complex
0.33	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.40	EC:6.3.3.2	GO:0030272
0.40	KEGG:R02301	GO:0030272

tr|Q0E8X9|Q0E8X9_DROME
FI08136p
Search

0.52	proteasome subunit beta type-2

0.72

GO:0051603

proteolysis involved in cellular protein catabolic process

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.76

GO:0005839

proteasome core complex

tr|Q0E8Y1|Q0E8Y1_DROME
Phosphatidylinositol 4-phosphate 5-kinase at 59B, isoform I
Search

0.71	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.50	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.49	GO:0007603	phototransduction, visible light
0.48	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.46	GO:0071482	cellular response to light stimulus

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0035997	rhabdomere microvillus membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0016307

tr|Q0E906|Q0E906_DROME
GEO11031p1
Search

0.32	Putative secreted protein (Fragment)

0.30

GO:0044425

membrane part

sp|Q0E908|HIL_DROME
Hillarin
Search

0.78	Tgc transglutaminase/protease like domain containing protein involved in cytokinesis

0.39	GO:0006508	proteolysis
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.53	GO:0046872	metal ion binding
0.39	GO:0008233	peptidase activity
0.34	GO:0005515	protein binding

0.51	GO:0097610	cell surface furrow
0.49	GO:0032155	cell division site part
0.47	GO:0005938	cell cortex
0.34	GO:0005911	cell-cell junction
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0008233

tr|Q0E910|Q0E910_DROME
CG8920, isoform B
Search

0.87	GO:1990511	piRNA biosynthetic process
0.86	GO:0010529	negative regulation of transposition

0.85	GO:0043186	P granule
0.79	GO:0048471	perinuclear region of cytoplasm

tr|Q0E931|Q0E931_DROME
Dgp-1, isoform A
Search

0.38	Elongation factor Tu

0.40	GO:0006414	translational elongation
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0006508	proteolysis

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003746	translation elongation factor activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0004803	transposase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003677	DNA binding

0.33

GO:0005840

ribosome

0.33

GO:0004222

tr|Q0E938|Q0E938_DROME
CG6424, isoform A
Search

0.50

GO:0007165

signal transduction

0.37	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|Q0E940|EIF3B_DROME
Eukaryotic translation initiation factor 3 subunit B
Search

0.69	Eukaryotic translation initiation factor 3 subunit B

0.76	GO:0006446	regulation of translational initiation
0.74	GO:0001731	formation of translation preinitiation complex
0.47	GO:0030707	ovarian follicle cell development
0.46	GO:0075525	viral translational termination-reinitiation
0.46	GO:0075522	IRES-dependent viral translational initiation
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.83	GO:0031369	translation initiation factor binding
0.73	GO:0003743	translation initiation factor activity
0.35	GO:0003729	mRNA binding
0.34	GO:0032947	protein complex scaffold activity
0.33	GO:0046872	metal ion binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.73	GO:0016282	eukaryotic 43S preinitiation complex
0.73	GO:0033290	eukaryotic 48S preinitiation complex
0.35	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol

tr|Q0E949|Q0E949_DROME
CG5522, isoform A
Search

RALGPS2

0.81	Ral guanine nucleotide exchange factor

0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0032485	regulation of Ral protein signal transduction

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.41	GO:0017160	Ral GTPase binding

0.45	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane

sp|Q0E959|RM34_DROME
39S ribosomal protein L34, mitochondrial
Search

0.83	39S ribosomal protein L34, mitochondrial

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005840	ribosome
0.39	GO:0005759	mitochondrial matrix

tr|Q0E960|Q0E960_DROME
CG8389, isoform A
Search

0.52	Monocarboxylate transporter 12

0.55	GO:0055085	transmembrane transport
0.39	GO:0015718	monocarboxylic acid transport
0.35	GO:0006468	protein phosphorylation

0.39	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

tr|Q0E961|Q0E961_DROME
Bedraggled, isoform A
Search

0.67	Sodium/chloride dependent transporter

0.76	GO:0006836	neurotransmitter transport
0.68	GO:0007464	R3/R4 cell fate commitment
0.54	GO:0055085	transmembrane transport

0.78	GO:0005328	neurotransmitter:sodium symporter activity
0.32	GO:0046872	metal ion binding

0.37

GO:0005887

integral component of plasma membrane

tr|Q0E980|Q0E980_DROME
CG8547, isoform C
Search

0.66	GO:0006457	protein folding
0.40	GO:0016575	histone deacetylation

0.68	GO:0051082	unfolded protein binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.47

GO:0005581

collagen trimer

tr|Q0E981|Q0E981_DROME
CG8485, isoform A
Search

SNRK

0.54	Snf-related serine threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.38	GO:0035556	intracellular signal transduction
0.34	GO:0042981	regulation of apoptotic process
0.34	GO:0060217	hemangioblast cell differentiation
0.34	GO:1901214	regulation of neuron death
0.34	GO:0006885	regulation of pH
0.34	GO:0035725	sodium ion transmembrane transport
0.33	GO:0043069	negative regulation of programmed cell death
0.33	GO:1902600	hydrogen ion transmembrane transport

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0000287	magnesium ion binding
0.34	GO:0015385	sodium:proton antiporter activity

0.37	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q0E985|Q0E985_DROME
RH74701p
Search

0.69

GO:0035167

larval lymph gland hemopoiesis

0.35	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|Q0E9A0|Q0E9A0_DROME
FI21293p1
Search

0.11	Trihelix transcription factor GT-1

0.30

GO:0008152

metabolic process

0.35	GO:0003676	nucleic acid binding
0.30	GO:0003824	catalytic activity

tr|Q0E9A5|Q0E9A5_DROME
FI21269p1
Search

MKLN1

0.86

muskelin

0.77	GO:0001556	oocyte maturation
0.59	GO:0007160	cell-matrix adhesion
0.56	GO:0031532	actin cytoskeleton reorganization
0.53	GO:0001952	regulation of cell-matrix adhesion
0.52	GO:0008360	regulation of cell shape
0.34	GO:0007165	signal transduction

0.54	GO:0042802	identical protein binding
0.39	GO:0008017	microtubule binding

0.60	GO:0001726	ruffle
0.56	GO:0005938	cell cortex
0.52	GO:0005829	cytosol
0.39	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

tr|Q0E9A7|Q0E9A7_DROME
Uncharacterized protein, isoform E
Search

0.67	Heterotrimeric GTP-binding protein alpha subunit G-alpha-q

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0007603	phototransduction, visible light
0.41	GO:0009649	entrainment of circadian clock
0.41	GO:1905145	cellular response to acetylcholine
0.41	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.41	GO:0035412	regulation of catenin import into nucleus
0.40	GO:0045634	regulation of melanocyte differentiation
0.40	GO:0042711	maternal behavior
0.40	GO:0001508	action potential
0.40	GO:0019933	cAMP-mediated signaling

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.80	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.39	GO:0005096	GTPase activator activity
0.35	GO:0002046	opsin binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016874	ligase activity

0.42	GO:1905360	GTPase complex
0.41	GO:0001750	photoreceptor outer segment
0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0030425	dendrite
0.38	GO:0044297	cell body
0.38	GO:0098797	plasma membrane protein complex
0.35	GO:0097232	lamellar body membrane
0.35	GO:0016028	rhabdomere
0.34	GO:0005765	lysosomal membrane
0.34	GO:0070062	extracellular exosome

0.33

GO:0016874

tr|Q0E9B1|Q0E9B1_DROME
Uncharacterized protein
Search

0.39	GO:0042387	plasmatocyte differentiation
0.39	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.38	GO:0035206	regulation of hemocyte proliferation
0.38	GO:0035006	melanization defense response
0.38	GO:0007017	microtubule-based process
0.38	GO:0007010	cytoskeleton organization
0.38	GO:0048935	peripheral nervous system neuron development
0.36	GO:0006366	transcription by RNA polymerase II
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0010629	negative regulation of gene expression

0.40	GO:0070379	high mobility group box 1 binding
0.39	GO:0005200	structural constituent of cytoskeleton
0.38	GO:0070491	repressing transcription factor binding
0.38	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.38	GO:0003924	GTPase activity
0.37	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0032561	guanyl ribonucleotide binding
0.37	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.36	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.39	GO:0071212	subsynaptic reticulum
0.39	GO:0005874	microtubule
0.38	GO:0031594	neuromuscular junction
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.36

GO:0016747

tr|Q0E9B5|Q0E9B5_DROME
CG8841, isoform A
Search

0.10	HID1 domain containing

0.68	GO:0031001	response to brefeldin A
0.64	GO:0006886	intracellular protein transport
0.43	GO:0006413	translational initiation

0.34

GO:0005515

protein binding

0.81	GO:0000138	Golgi trans cisterna
0.79	GO:0005797	Golgi medial cisterna
0.64	GO:0090498	extrinsic component of Golgi membrane
0.60	GO:0005881	cytoplasmic microtubule
0.52	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q0E9B6|RS11_DROME
40S ribosomal protein S11
Search

RPS11

0.53	Ribosomal protein 4

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.33	GO:0045454	cell redox homeostasis

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0019843	rRNA binding

0.61	GO:0005840	ribosome
0.44	GO:0000228	nuclear chromosome
0.44	GO:0005730	nucleolus
0.38	GO:0044445	cytosolic part
0.30	GO:0031224	intrinsic component of membrane

tr|Q0E9B7|Q0E9B7_DROME
DNAation factor-related protein 3, isoform A
Search

0.11	DNAation factor-related protein 3, isoform A

0.78	GO:0006915	apoptotic process
0.39	GO:0042981	regulation of apoptotic process
0.34	GO:0000737	DNA catabolic process, endonucleolytic
0.33	GO:0022411	cellular component disassembly
0.33	GO:0055085	transmembrane transport

0.37	GO:0005515	protein binding
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

tr|Q0E9E0|Q0E9E0_DROME
FI05255p
Search

LOC108093896

0.95	SPARC-related modular calcium-binding protein 2 isoform X2

0.70	GO:0044719	regulation of imaginal disc-derived wing size
0.68	GO:0030718	germ-line stem cell population maintenance
0.67	GO:0030513	positive regulation of BMP signaling pathway
0.66	GO:0008340	determination of adult lifespan
0.61	GO:0007165	signal transduction
0.32	GO:0010951	negative regulation of endopeptidase activity

0.70	GO:0005509	calcium ion binding
0.68	GO:0043395	heparan sulfate proteoglycan binding
0.32	GO:0004867	serine-type endopeptidase inhibitor activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.64	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q0E9E2|Q0E9E2_DROME
Pyruvate carboxylase
Search

0.54	Pyruvate carboxylase, mitochondrial

0.72	GO:0006094	gluconeogenesis
0.68	GO:0006090	pyruvate metabolic process

0.82	GO:0009374	biotin binding
0.81	GO:0004736	pyruvate carboxylase activity
0.76	GO:0004075	biotin carboxylase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.33	GO:0016829	lyase activity

0.36	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:6.4.1.1	GO:0004736
0.81	KEGG:R00344	GO:0004736

tr|Q0E9F2|Q0E9F2_DROME
Sticks and stones, isoform B
Search

0.55	Sticks and stones, isoform B

0.40	GO:0061321	garland nephrocyte differentiation
0.40	GO:0036059	nephrocyte diaphragm assembly
0.40	GO:0097206	nephrocyte filtration
0.40	GO:0007523	larval visceral muscle development
0.39	GO:0007520	myoblast fusion
0.39	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0001745	compound eye morphogenesis
0.38	GO:0007286	spermatid development
0.38	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0030036	actin cytoskeleton organization

0.33

GO:0005515

protein binding

0.40	GO:0005917	nephrocyte diaphragm
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q0E9F9|Q0E9F9_DROME
CG2915, isoform A
Search

0.38	zinc carboxypeptidase

0.61	GO:0006508	proteolysis
0.39	GO:0042730	fibrinolysis
0.36	GO:0008057	eye pigment granule organization
0.36	GO:0032483	regulation of Rab protein signal transduction
0.36	GO:0033060	ocellus pigmentation
0.35	GO:0006726	eye pigment biosynthetic process
0.35	GO:0010883	regulation of lipid storage
0.35	GO:0060967	negative regulation of gene silencing by RNA
0.34	GO:0010506	regulation of autophagy
0.34	GO:0044550	secondary metabolite biosynthetic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.35	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.32	GO:0003779	actin binding
0.32	GO:0005509	calcium ion binding

0.47	GO:0031982	vesicle
0.41	GO:0005615	extracellular space
0.36	GO:0012505	endomembrane system
0.33	GO:0008305	integrin complex
0.33	GO:0031012	extracellular matrix

0.78

EC:3.4.17

GO:0004181

sp|Q0E9G3|KTU_DROME
Protein kintoun
Search

0.85	GO:0070286	axonemal dynein complex assembly
0.78	GO:0060285	cilium-dependent cell motility
0.35	GO:0032526	response to retinoic acid
0.34	GO:0007016	cytoskeletal anchoring at plasma membrane
0.33	GO:0071897	DNA biosynthetic process
0.33	GO:0006260	DNA replication
0.33	GO:0007155	cell adhesion
0.33	GO:0000492	box C/D snoRNP assembly
0.32	GO:0006457	protein folding
0.32	GO:0006364	rRNA processing

0.63	GO:0008157	protein phosphatase 1 binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0051015	actin filament binding
0.33	GO:0005200	structural constituent of cytoskeleton
0.32	GO:0003677	DNA binding

0.48	GO:0005737	cytoplasm
0.34	GO:0001726	ruffle
0.34	GO:0005925	focal adhesion
0.33	GO:0005856	cytoskeleton
0.32	GO:0097255	R2TP complex
0.32	GO:0005732	small nucleolar ribonucleoprotein complex
0.30	GO:0016020	membrane

0.33

GO:0003887

tr|Q0E9N0|Q0E9N0_DROME
FI03272p
Search

0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0015937	coenzyme A biosynthetic process
0.47	GO:0006351	transcription, DNA-templated
0.43	GO:0034220	ion transmembrane transport
0.41	GO:0016310	phosphorylation

0.61	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.54	GO:0008270	zinc ion binding
0.52	GO:0050825	ice binding
0.50	GO:0004594	pantothenate kinase activity
0.48	GO:0008381	mechanosensitive ion channel activity
0.48	GO:0003677	DNA binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.50

EC:2.7.1.33

GO:0004594

tr|Q0E9N4|Q0E9N4_DROME
CG9422, isoform A
Search

0.74	Putative ribonuclease p protein (Fragment)

0.39	GO:0001682	tRNA 5'-leader removal
0.38	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.58	GO:0003723	RNA binding
0.54	GO:0003677	DNA binding
0.39	GO:0004526	ribonuclease P activity

0.48	GO:0005737	cytoplasm
0.40	GO:0030681	multimeric ribonuclease P complex
0.40	GO:0000172	ribonuclease MRP complex

0.39

EC:3.1.26.5

GO:0004526

tr|Q0IGP7|Q0IGP7_DROME
SD20656p
Search

0.35	GO:0000413	protein peptidyl-prolyl isomerization
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0070417	cellular response to cold
0.34	GO:0000027	ribosomal large subunit assembly
0.34	GO:0006353	DNA-templated transcription, termination
0.33	GO:0000271	polysaccharide biosynthetic process
0.33	GO:0006898	receptor-mediated endocytosis
0.33	GO:0006401	RNA catabolic process
0.32	GO:0055085	transmembrane transport

0.57	GO:0003723	RNA binding
0.36	GO:0046872	metal ion binding
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0008186	RNA-dependent ATPase activity
0.35	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0004386	helicase activity
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.34	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:5.2.1.8

GO:0003755

tr|Q0IGQ2|Q0IGQ2_DROME
Bteb2
Search

0.52	Krueppel-like factor 6

0.57	GO:0061318	renal filtration cell differentiation
0.54	GO:0010272	response to silver ion
0.54	GO:0036059	nephrocyte diaphragm assembly
0.51	GO:0001700	embryonic development via the syncytial blastoderm
0.47	GO:0003299	muscle hypertrophy in response to stress
0.47	GO:0014887	cardiac muscle adaptation
0.47	GO:0003300	cardiac muscle hypertrophy
0.47	GO:2000757	negative regulation of peptidyl-lysine acetylation
0.47	GO:0072311	glomerular epithelial cell differentiation
0.45	GO:0010001	glial cell differentiation

0.51	GO:0003676	nucleic acid binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.40	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|Q0IGR3|Q0IGR3_DROME
CG2120
Search

0.10	zinc finger protein 239

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0035914	skeletal muscle cell differentiation
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0051052	regulation of DNA metabolic process
0.33	GO:0031167	rRNA methylation
0.32	GO:0006974	cellular response to DNA damage stimulus

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.37	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0016433	rRNA (adenine) methyltransferase activity
0.33	GO:0042803	protein homodimerization activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.49	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.32	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0016433

tr|Q0IGS7|Q0IGS7_DROME
Palmitoyltransferase
Search

0.53	Palmitoyltransferase

0.44	GO:0018345	protein palmitoylation
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.32	GO:0016491	oxidoreductase activity

0.54	GO:0005783	endoplasmic reticulum
0.35	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.3.1.225

GO:0019706

tr|Q0IGT4|Q0IGT4_DROME
Cousin of atonal
Search

0.67	Basic helix-loop-helix transcription factor amos

0.50	GO:0007423	sensory organ development
0.40	GO:0045138	nematode male tail tip morphogenesis
0.38	GO:0030182	neuron differentiation
0.38	GO:0009792	embryo development ending in birth or egg hatching
0.38	GO:0048468	cell development
0.34	GO:0051179	localization
0.34	GO:0060563	neuroepithelial cell differentiation
0.34	GO:0009913	epidermal cell differentiation
0.32	GO:0032774	RNA biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.37	GO:0042802	identical protein binding
0.36	GO:0043565	sequence-specific DNA binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0003899

tr|Q0IGU7|Q0IGU7_DROME
HLH54F
Search

0.10	neurogenic differentiation factor 1

0.64	GO:0007517	muscle organ development
0.57	GO:0006357	regulation of transcription by RNA polymerase II
0.56	GO:0060021	palate development
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0014706	striated muscle tissue development
0.54	GO:0060541	respiratory system development
0.54	GO:0072277	metanephric glomerular capillary formation
0.54	GO:0072162	metanephric mesenchymal cell differentiation
0.53	GO:0060766	negative regulation of androgen receptor signaling pathway
0.51	GO:0001658	branching involved in ureteric bud morphogenesis

0.68	GO:0046983	protein dimerization activity
0.55	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.51	GO:0043425	bHLH transcription factor binding
0.51	GO:0050681	androgen receptor binding
0.50	GO:0042826	histone deacetylase binding
0.49	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0000987	proximal promoter sequence-specific DNA binding
0.47	GO:0001158	enhancer sequence-specific DNA binding
0.47	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.47	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

tr|Q0IGX4|Q0IGX4_DROME
CG7882, isoform A
Search

0.47	Glucose transporter

0.55	GO:0055085	transmembrane transport
0.53	GO:0008643	carbohydrate transport
0.36	GO:0001889	liver development
0.36	GO:0042593	glucose homeostasis
0.36	GO:0007420	brain development
0.35	GO:0032869	cellular response to insulin stimulus
0.35	GO:0010021	amylopectin biosynthetic process
0.34	GO:0050873	brown fat cell differentiation
0.34	GO:0071356	cellular response to tumor necrosis factor
0.34	GO:0071470	cellular response to osmotic stress

0.57	GO:0022857	transmembrane transporter activity
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0032593	insulin-responsive compartment
0.34	GO:0042383	sarcolemma
0.34	GO:0030140	trans-Golgi network transport vesicle
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0045121	membrane raft
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005768	endosome
0.33	GO:0005829	cytosol

0.32

GO:0004674

tr|Q0IGY6|Q0IGY6_DROME
IP07646p
Search

0.36

GO:0022008

neurogenesis

0.32	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|Q0IGY7|Q0IGY7_DROME
CG5267
Search

0.76	GO:0032504	multicellular organism reproduction
0.73	GO:0007620	copulation
0.66	GO:0044706	multi-multicellular organism process
0.63	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0051260	protein homooligomerization
0.43	GO:0007610	behavior

0.65	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0042803	protein homodimerization activity

0.72	GO:0005615	extracellular space
0.41	GO:0005783	endoplasmic reticulum

tr|Q0IGZ2|Q0IGZ2_DROME
IP05237p
Search

0.54	GO:0030521	androgen receptor signaling pathway
0.47	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.41	GO:0048813	dendrite morphogenesis
0.41	GO:0006367	transcription initiation from RNA polymerase II promoter
0.41	GO:0018108	peptidyl-tyrosine phosphorylation
0.41	GO:1902275	regulation of chromatin organization

0.55	GO:0004882	androgen receptor activity
0.52	GO:0005496	steroid binding
0.43	GO:0003677	DNA binding
0.42	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.40	GO:0003712	transcription cofactor activity
0.40	GO:0046982	protein heterodimerization activity
0.39	GO:0004386	helicase activity
0.38	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.38	GO:0016757	transferase activity, transferring glycosyl groups
0.38	GO:0140101	catalytic activity, acting on a tRNA

0.49	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.44	GO:0005667	transcription factor complex
0.42	GO:0044446	intracellular organelle part
0.42	GO:1902494	catalytic complex
0.38	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.42

EC:2.7.10.2

GO:0004715

tr|Q0KHN6|Q0KHN6_DROME
Uncharacterized protein, isoform C
Search

0.54

chaoptin

0.34	GO:0036211	protein modification process
0.33	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:1903077	negative regulation of protein localization to plasma membrane
0.33	GO:0009554	megasporogenesis
0.33	GO:0009556	microsporogenesis
0.33	GO:0048658	anther wall tapetum development
0.33	GO:0046813	receptor-mediated virion attachment to host cell
0.33	GO:0030335	positive regulation of cell migration
0.32	GO:0022904	respiratory electron transport chain

0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0001968	fibronectin binding
0.33	GO:0043236	laminin binding
0.33	GO:0005518	collagen binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0016791	phosphatase activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005634	nucleus
0.32	GO:0005750	mitochondrial respiratory chain complex III
0.32	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

0.33

GO:0016773

tr|Q0KHQ1|Q0KHQ1_DROME
GEO13361p1
Search

0.24	SRA stem-loop-interacting RNA-binding protein, mitochondrial

0.45	GO:0007281	germ cell development
0.44	GO:0045727	positive regulation of translation
0.39	GO:0006972	hyperosmotic response
0.39	GO:0008340	determination of adult lifespan
0.38	GO:0009408	response to heat
0.38	GO:0007147	female meiosis II
0.37	GO:0045836	positive regulation of meiotic nuclear division
0.37	GO:0071695	anatomical structure maturation
0.37	GO:0048469	cell maturation
0.36	GO:0006446	regulation of translational initiation

0.59	GO:0003723	RNA binding
0.48	GO:0008494	translation activator activity
0.36	GO:0042802	identical protein binding

0.37	GO:0005844	polysome
0.36	GO:0005634	nucleus
0.35	GO:0030014	CCR4-NOT complex
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q0KHQ5|TAO_DROME
Serine/threonine-protein kinase Tao
Search

0.55	Serine/threonine-protein kinase SULU

0.65	GO:0048036	central complex development
0.64	GO:0035332	positive regulation of hippo signaling
0.63	GO:0036335	intestinal stem cell homeostasis
0.63	GO:0006468	protein phosphorylation
0.62	GO:0042220	response to cocaine
0.62	GO:0016319	mushroom body development
0.62	GO:0035094	response to nicotine
0.62	GO:0046621	negative regulation of organ growth
0.60	GO:0035329	hippo signaling
0.60	GO:0045471	response to ethanol

0.63	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0005515	protein binding
0.32	GO:0004725	protein tyrosine phosphatase activity
0.31	GO:0003735	structural constituent of ribosome
0.31	GO:0046872	metal ion binding

0.61	GO:0045178	basal part of cell
0.56	GO:0005819	spindle
0.54	GO:0005874	microtubule
0.44	GO:0005886	plasma membrane
0.40	GO:0030424	axon
0.40	GO:0036477	somatodendritic compartment
0.39	GO:0044297	cell body
0.38	GO:0005938	cell cortex
0.36	GO:0030426	growth cone
0.35	GO:0043235	receptor complex

0.32

GO:0004725

tr|Q0KHR2|Q0KHR2_DROME
Forked, isoform F
Search

0.97	Forked, isoform F

0.86	GO:0048800	antennal morphogenesis
0.85	GO:0035017	cuticle pattern formation
0.85	GO:0008407	chaeta morphogenesis
0.85	GO:0035317	imaginal disc-derived wing hair organization
0.80	GO:0051017	actin filament bundle assembly
0.79	GO:0007605	sensory perception of sound
0.39	GO:0016310	phosphorylation
0.39	GO:0097017	renal protein absorption
0.39	GO:0097206	nephrocyte filtration

0.64	GO:0003779	actin binding
0.45	GO:0032403	protein complex binding
0.40	GO:0016301	kinase activity

0.84	GO:0031941	filamentous actin
0.36	GO:0005737	cytoplasm

tr|Q0KHR3|Q0KHR3_DROME
Bazooka, isoform B
Search

0.92	partitioning defective 3 homolog isoform X3

0.88	GO:0007299	ovarian follicle cell-cell adhesion
0.87	GO:0030709	border follicle cell delamination
0.87	GO:0045186	zonula adherens assembly
0.87	GO:0051490	negative regulation of filopodium assembly
0.87	GO:0007377	germ-band extension
0.87	GO:0090250	cell-cell adhesion involved in establishment of planar polarity
0.87	GO:0045167	asymmetric protein localization involved in cell fate determination
0.86	GO:0008594	photoreceptor cell morphogenesis
0.86	GO:0007294	germarium-derived oocyte fate determination
0.86	GO:0016325	oocyte microtubule cytoskeleton organization

0.86	GO:0070300	phosphatidic acid binding
0.76	GO:0035091	phosphatidylinositol binding
0.50	GO:0005515	protein binding

0.87	GO:0005914	spot adherens junction
0.86	GO:0005915	zonula adherens
0.85	GO:0098592	cytoplasmic side of apical plasma membrane
0.68	GO:0035003	subapical complex
0.65	GO:0016327	apicolateral plasma membrane
0.65	GO:0045179	apical cortex

tr|Q0KHR4|Q0KHR4_DROME
FI21203p1
Search

0.85	GO:0016321	female meiosis chromosome segregation
0.79	GO:0007131	reciprocal meiotic recombination
0.45	GO:0006270	DNA replication initiation
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.38	GO:0003677	DNA binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003713	transcription coactivator activity

0.48

GO:0005737

cytoplasm

tr|Q0KHR7|Q0KHR7_DROME
Septin 4, isoform A
Search

0.63

Septin

0.46	GO:0051301	cell division
0.45	GO:0007049	cell cycle
0.36	GO:0016311	dephosphorylation
0.35	GO:0005975	carbohydrate metabolic process
0.34	GO:0090163	establishment of epithelial cell planar polarity
0.34	GO:0060271	cilium assembly
0.34	GO:0060031	mediolateral intercalation
0.34	GO:0016476	regulation of embryonic cell shape
0.33	GO:0072114	pronephros morphogenesis

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity
0.37	GO:0003924	GTPase activity

0.44	GO:0032156	septin cytoskeleton
0.42	GO:0044448	cell cortex part
0.40	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.34	GO:0032154	cleavage furrow
0.33	GO:0030496	midbody
0.33	GO:0097014	ciliary plasm
0.33	GO:0016324	apical plasma membrane
0.33	GO:0000779	condensed chromosome, centromeric region
0.33	GO:0015630	microtubule cytoskeleton

0.37

EC:3.1.3.11

GO:0042132

tr|Q0KHS0|Q0KHS0_DROME
Katanin p80 WD40 repeat-containing subunit B1
Search

0.75	Katanin p80 WD40 repeat-containing subunit B1

0.83	GO:0051013	microtubule severing
0.61	GO:0046843	dorsal appendage formation
0.60	GO:0051301	cell division
0.60	GO:0007049	cell cycle
0.35	GO:0045943	positive regulation of transcription by RNA polymerase I
0.35	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.34	GO:0043622	cortical microtubule organization
0.32	GO:0070682	proteasome regulatory particle assembly
0.32	GO:0006468	protein phosphorylation
0.32	GO:0006511	ubiquitin-dependent protein catabolic process

0.73	GO:0008017	microtubule binding
0.35	GO:0030515	snoRNA binding
0.34	GO:0043531	ADP binding
0.32	GO:0016740	transferase activity
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0003677	DNA binding
0.31	GO:0005524	ATP binding

0.85	GO:0008352	katanin complex
0.71	GO:0005874	microtubule
0.70	GO:0000922	spindle pole
0.69	GO:0005813	centrosome
0.43	GO:0005829	cytosol
0.35	GO:0034455	t-UTP complex
0.35	GO:0033553	rDNA heterochromatin
0.34	GO:0032040	small-subunit processome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|Q0KHT7|DAPKR_DROME
Death-associated protein kinase related
Search

0.75	Death-associated protein kinase related

0.63	GO:0006468	protein phosphorylation
0.55	GO:0007480	imaginal disc-derived leg morphogenesis
0.54	GO:0007476	imaginal disc-derived wing morphogenesis
0.41	GO:0035023	regulation of Rho protein signal transduction
0.39	GO:0065009	regulation of molecular function
0.37	GO:0045599	negative regulation of fat cell differentiation
0.34	GO:1905905	pharyngeal gland morphogenesis
0.34	GO:0030241	skeletal muscle myosin thick filament assembly
0.34	GO:0045989	positive regulation of striated muscle contraction
0.33	GO:0040017	positive regulation of locomotion

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0090736	MATH domain binding
0.33	GO:0019902	phosphatase binding

0.37	GO:0005634	nucleus
0.33	GO:0031430	M band
0.30	GO:0031224	intrinsic component of membrane

tr|Q0KHU0|Q0KHU0_DROME
Myosin 10A, isoform D
Search

MYO15

0.48	Unconventional myosin-XV

0.80	GO:0007605	sensory perception of sound
0.68	GO:0007018	microtubule-based movement
0.51	GO:0046847	filopodium assembly
0.50	GO:0007391	dorsal closure
0.44	GO:0006886	intracellular protein transport
0.33	GO:0006364	rRNA processing
0.33	GO:0032259	methylation

0.72	GO:0003779	actin binding
0.69	GO:0003777	microtubule motor activity
0.69	GO:0008017	microtubule binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0042623	ATPase activity, coupled
0.33	GO:0008168	methyltransferase activity

0.75	GO:0016459	myosin complex
0.49	GO:0030175	filopodium
0.48	GO:0043025	neuronal cell body
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0008168

tr|Q0KHU4|Q0KHU4_DROME
RhoU, isoform B
Search

0.11	RhoU, isoform B

0.75	GO:0007264	small GTPase mediated signal transduction
0.42	GO:0036302	atrioventricular canal development
0.39	GO:0030155	regulation of cell adhesion
0.36	GO:0071896	protein localization to adherens junction
0.36	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.36	GO:1903955	positive regulation of protein targeting to mitochondrion
0.34	GO:0007010	cytoskeleton organization
0.34	GO:0008360	regulation of cell shape
0.33	GO:0051056	regulation of small GTPase mediated signal transduction

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.36	GO:0031982	vesicle
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0012505	endomembrane system
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q0KHU5|PCAT_DROME
Lysophosphatidylcholine acyltransferase
Search

0.38	Lysophosphatidylcholine acyltransferase

0.47	GO:0030258	lipid modification
0.41	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.40	GO:2001246	negative regulation of phosphatidylcholine biosynthetic process
0.40	GO:0043129	surfactant homeostasis
0.39	GO:0008654	phospholipid biosynthetic process
0.39	GO:0060041	retina development in camera-type eye
0.38	GO:0045732	positive regulation of protein catabolic process

0.63	GO:0016746	transferase activity, transferring acyl groups
0.60	GO:0005509	calcium ion binding

0.52	GO:0005811	lipid droplet
0.39	GO:0005783	endoplasmic reticulum
0.39	GO:0005794	Golgi apparatus
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:2.3

GO:0016746

tr|Q0KHV6|Q0KHV6_DROME
FI19430p1
Search

PINK1

0.21	Serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.62	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone
0.60	GO:0048078	positive regulation of compound eye pigmentation
0.60	GO:0090140	regulation of mitochondrial fission
0.60	GO:0030382	sperm mitochondrion organization
0.60	GO:0010637	negative regulation of mitochondrial fusion
0.59	GO:0035234	ectopic germ cell programmed cell death
0.58	GO:0061726	mitochondrion disassembly
0.58	GO:0010822	positive regulation of mitochondrion organization
0.57	GO:0047497	mitochondrion transport along microtubule

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0055131	C3HC4-type RING finger domain binding
0.40	GO:0043422	protein kinase B binding
0.39	GO:0002020	protease binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0000287	magnesium ion binding

0.60	GO:0016006	Nebenkern
0.40	GO:0097449	astrocyte projection
0.38	GO:0005742	mitochondrial outer membrane translocase complex
0.38	GO:0031307	integral component of mitochondrial outer membrane
0.38	GO:0031932	TORC2 complex
0.38	GO:0044297	cell body
0.38	GO:0030424	axon
0.38	GO:0005758	mitochondrial intermembrane space
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005829	cytosol

tr|Q0KHW3|Q0KHW3_DROME
Pickpocket 8, isoform H
Search

0.61	pickpocket protein 28

0.77	GO:0035725	sodium ion transmembrane transport
0.33	GO:0035199	salt aversion
0.33	GO:0050914	sensory perception of salty taste
0.33	GO:0035002	liquid clearance, open tracheal system
0.33	GO:0060025	regulation of synaptic activity
0.32	GO:0055078	sodium ion homeostasis
0.32	GO:0009651	response to salt stress
0.32	GO:0050891	multicellular organismal water homeostasis

0.81	GO:0005272	sodium channel activity
0.37	GO:0099094	ligand-gated cation channel activity
0.32	GO:0050699	WW domain binding

0.32	GO:0060170	ciliary membrane
0.32	GO:0034706	sodium channel complex
0.32	GO:0016324	apical plasma membrane
0.32	GO:0070062	extracellular exosome
0.32	GO:0031514	motile cilium
0.32	GO:0005887	integral component of plasma membrane
0.31	GO:0005737	cytoplasm

tr|Q0KHX4|Q0KHX4_DROME
GH03322p1
Search

0.86	venom peptide CtAPI

0.78	GO:0042381	hemolymph coagulation
0.45	GO:0006898	receptor-mediated endocytosis

0.65	GO:0042803	protein homodimerization activity
0.49	GO:0005044	scavenger receptor activity
0.48	GO:0001871	pattern binding
0.45	GO:0030246	carbohydrate binding

0.58	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|Q0KHX7|Q0KHX7_DROME
FI18193p1
Search

0.68	Cytospin-A

0.82	GO:0048734	proboscis morphogenesis
0.79	GO:0048802	notum morphogenesis
0.78	GO:0007527	adult somatic muscle development
0.73	GO:0045214	sarcomere organization
0.43	GO:0051301	cell division
0.43	GO:0007049	cell cycle
0.42	GO:0009966	regulation of signal transduction
0.42	GO:0007026	negative regulation of microtubule depolymerization
0.41	GO:0065009	regulation of molecular function
0.40	GO:0030835	negative regulation of actin filament depolymerization

0.43	GO:0004386	helicase activity
0.42	GO:0098772	molecular function regulator
0.40	GO:0005102	receptor binding
0.39	GO:0017048	Rho GTPase binding
0.39	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0003676	nucleic acid binding

0.47	GO:0005921	gap junction
0.46	GO:0005819	spindle
0.41	GO:0031941	filamentous actin
0.39	GO:0005815	microtubule organizing center
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

GO:0004725

sp|Q0KHY3|MESH_DROME
Protein mesh
Search

Y1004

0.95	Extracellular domains-containing protein CG31004

0.81	GO:0007160	cell-matrix adhesion
0.48	GO:0090528	smooth septate junction assembly
0.34	GO:0007275	multicellular organism development

0.34

GO:0005515

protein binding

0.47	GO:0005920	smooth septate junction
0.36	GO:0016327	apicolateral plasma membrane
0.34	GO:0016328	lateral plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q0KHY5|Q0KHY5_DROME
Uncharacterized protein
Search

tr|Q0KHY7|Q0KHY7_DROME
Uncharacterized protein, isoform B
Search

0.69	prolyl 4-hydroxylase subunit alpha-2-like

0.81	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0032504	multicellular organism reproduction
0.34	GO:0051321	meiotic cell cycle

0.82	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.72	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding

0.68	GO:0005783	endoplasmic reticulum
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.14.11.2	GO:0004656
0.82	KEGG:R03219	GO:0004656

tr|Q0KHY8|Q0KHY8_DROME
Uncharacterized protein, isoform B
Search

VAS1

0.66	Lysosome-associated membrane glycoprotein (Lamp)

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.42	GO:0006801	superoxide metabolic process
0.32	GO:0033554	cellular response to stress

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.37	GO:0046872	metal ion binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.33	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

tr|Q0KHZ2|Q0KHZ2_DROME
GEO05146p1
Search

0.52	GO:0046146	tetrahydrobiopterin metabolic process
0.52	GO:0034312	diol biosynthetic process
0.49	GO:0042559	pteridine-containing compound biosynthetic process
0.45	GO:0009108	coenzyme biosynthetic process
0.40	GO:0055114	oxidation-reduction process

0.57

GO:0004757

sepiapterin reductase activity

0.57

EC:1.1.1.153

GO:0004757

tr|Q0KHZ6|Q0KHZ6_DROME
CG7834, isoform A
Search

0.41	Electron-transfer-flavoprotein beta polypeptide

0.61	GO:0022900	electron transport chain
0.48	GO:0007406	negative regulation of neuroblast proliferation
0.36	GO:0000338	protein deneddylation
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.34	GO:0007034	vacuolar transport

0.62

GO:0009055

electron transfer activity

0.39	GO:0005829	cytosol
0.38	GO:0045251	electron transfer flavoprotein complex
0.36	GO:0005759	mitochondrial matrix
0.36	GO:0008180	COP9 signalosome
0.35	GO:0098798	mitochondrial protein complex
0.30	GO:0016020	membrane

tr|Q0KI00|Q0KI00_DROME
FI20034p1
Search

0.51	Aminopeptidase N

0.61	GO:0006508	proteolysis
0.40	GO:0043171	peptide catabolic process
0.37	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.36	GO:1990947	exit from meiosis
0.35	GO:0030590	first cell cycle pseudocleavage
0.35	GO:1900195	positive regulation of oocyte maturation
0.35	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation
0.35	GO:0051661	maintenance of centrosome location
0.35	GO:0046662	regulation of oviposition
0.35	GO:0008595	anterior/posterior axis specification, embryo

0.69	GO:0004177	aminopeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding
0.40	GO:0042277	peptide binding
0.33	GO:0004126	cytidine deaminase activity

0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0097431	mitotic spindle pole
0.34	GO:0000793	condensed chromosome
0.32	GO:0005938	cell cortex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

EC:3.4.11

GO:0004177

tr|Q0KI05|Q0KI05_DROME
CG3339
Search

0.10	dynein beta chain, ciliary

0.74	GO:0007018	microtubule-based movement
0.43	GO:0007605	sensory perception of sound
0.35	GO:0030030	cell projection organization
0.33	GO:0006518	peptide metabolic process
0.33	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:1901566	organonitrogen compound biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process
0.31	GO:0006508	proteolysis

0.75	GO:0003777	microtubule motor activity
0.60	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0045503	dynein light chain binding
0.47	GO:0051959	dynein light intermediate chain binding
0.46	GO:0045505	dynein intermediate chain binding
0.33	GO:0003735	structural constituent of ribosome
0.31	GO:0004252	serine-type endopeptidase activity

0.78	GO:0030286	dynein complex
0.46	GO:0005930	axoneme
0.45	GO:0031514	motile cilium
0.36	GO:0005874	microtubule
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.60

GO:0016887

tr|Q0KI06|Q0KI06_DROME
CG5938, isoform A
Search

0.87	Cysteine-rich hydrophobic domain

0.34

GO:0007186

G-protein coupled receptor signaling pathway

0.34

GO:0004930

G-protein coupled receptor activity

0.35	GO:0005622	intracellular
0.34	GO:0031982	vesicle
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q0KI07|Q0KI07_DROME
IP19836p
Search

0.10	hypodermin-B

0.61	GO:0006508	proteolysis
0.51	GO:0032504	multicellular organism reproduction

0.69

GO:0004252

serine-type endopeptidase activity

0.49

GO:0005615

extracellular space

0.69

GO:0004252

tr|Q0KI14|Q0KI14_DROME
FI03229p
Search

ABCG8

0.19	Abc transporter

0.35

GO:0055085

transmembrane transport

0.60	GO:0016887	ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0015399	primary active transmembrane transporter activity

0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.60

GO:0016887

tr|Q0KI15|Q0KI15_DROME
GEO11096p1
Search

LYRM7

0.71	LYR motif-containing protein 7

0.60

GO:0019706

protein-cysteine S-palmitoyltransferase activity

0.30

GO:0031224

intrinsic component of membrane

0.60

EC:2.3.1.225

GO:0019706

tr|Q0KI22|Q0KI22_DROME
Uncharacterized protein, isoform B
Search

0.50

GO:0019216

regulation of lipid metabolic process

0.43	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|Q0KI25|Q0KI25_DROME
CG4467, isoform B
Search

0.68	Endoplasmic reticulum aminopeptidase 2

0.61	GO:0006508	proteolysis
0.42	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.39	GO:0008217	regulation of blood pressure
0.39	GO:0043171	peptide catabolic process
0.34	GO:0060177	regulation of angiotensin metabolic process
0.34	GO:0050886	endocrine process
0.33	GO:0042445	hormone metabolic process
0.33	GO:0051604	protein maturation
0.32	GO:0060395	SMAD protein signal transduction
0.32	GO:0007267	cell-cell signaling

0.67	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.48	GO:0004177	aminopeptidase activity
0.39	GO:0042277	peptide binding

0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.32	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0030659	cytoplasmic vesicle membrane
0.31	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.48

EC:3.4.11

GO:0004177

tr|Q0KI27|Q0KI27_DROME
Uncharacterized protein, isoform A
Search

0.91	Protein suppressor of variegation 3-7

0.55

GO:0003677

DNA binding

0.61

GO:0005634

nucleus

sp|Q0KI28|BL1S5_DROME
Biogenesis of lysosome-related organelles complex 1 subunit 5
Search

MUTED

0.62	Biogenesis of lysosome-related organelles complex 1 subunit 5

0.48	GO:0016197	endosomal transport
0.42	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly

0.84	GO:0031083	BLOC-1 complex
0.77	GO:0030133	transport vesicle
0.30	GO:0031224	intrinsic component of membrane

tr|Q0KI29|Q0KI29_DROME
Uncharacterized protein
Search

0.39

GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

0.30

GO:0044425

membrane part

0.39

GO:0016747

tr|Q0KI33|Q0KI33_DROME
CG7956, isoform F
Search

0.74	phosphatidylinositide phosphatase SAC2

0.32

GO:0055114

oxidation-reduction process

0.68	GO:0042578	phosphoric ester hydrolase activity
0.35	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.35	GO:0031418	L-ascorbic acid binding
0.33	GO:0005506	iron ion binding

0.30

GO:0031224

intrinsic component of membrane

0.68

EC:3.1

GO:0042578

tr|Q0KI42|Q0KI42_DROME
FI04462p
Search

0.63	Ionotropic receptor GluIID

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.55	GO:0007274	neuromuscular synaptic transmission
0.54	GO:0030510	regulation of BMP signaling pathway
0.53	GO:0019722	calcium-mediated signaling
0.50	GO:0006816	calcium ion transport
0.49	GO:0043179	rhythmic excitation
0.41	GO:0060025	regulation of synaptic activity
0.39	GO:0035249	synaptic transmission, glutamatergic

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.54	GO:0099604	ligand-gated calcium channel activity
0.38	GO:0005272	sodium channel activity
0.38	GO:0098782	mechanosensitived potassium channel activity
0.34	GO:0046332	SMAD binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.57	GO:0097482	muscle cell postsynaptic specialization
0.55	GO:0008328	ionotropic glutamate receptor complex
0.37	GO:0005622	intracellular

tr|Q0KI77|Q0KI77_DROME
Lipase
Search

0.46	Triacylglycerol lipase (Fragment)

0.64	GO:0016042	lipid catabolic process
0.40	GO:0007586	digestion
0.35	GO:0002213	defense response to insect
0.35	GO:0032504	multicellular organism reproduction

0.59

GO:0016788

hydrolase activity, acting on ester bonds

0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.59

EC:3.1

GO:0016788

tr|Q0KI81|Q0KI81_DROME
IP14232p
Search

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0000272	polysaccharide catabolic process
0.32	GO:0007399	nervous system development
0.32	GO:0030154	cell differentiation
0.32	GO:0045491	xylan metabolic process
0.32	GO:1902476	chloride transmembrane transport
0.32	GO:0006468	protein phosphorylation

0.73	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0050254	rhodopsin kinase activity
0.32	GO:0015377	cation:chloride symporter activity
0.32	GO:0030248	cellulose binding
0.32	GO:0031176	endo-1,4-beta-xylanase activity

0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.73

GO:0004725

tr|Q0KI85|Q0KI85_DROME
Uncharacterized protein, isoform B
Search

0.49	synaptogenesis protein syg-2 isoform X3

0.36

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|Q0KI89|Q0KI89_DROME
GEO10781p1
Search

tr|Q0KI91|Q0KI91_DROME
Uncharacterized protein
Search

MCFD2

0.67	Multiple coagulation factor deficiency protein 2

0.70

GO:0005509

calcium ion binding

tr|Q0KI93|Q0KI93_DROME
Whamy, isoform B
Search

WHAMY

0.97	Whamy, isoform B

0.77	GO:0007520	myoblast fusion
0.76	GO:0051127	positive regulation of actin nucleation
0.74	GO:0001578	microtubule bundle formation
0.69	GO:0016477	cell migration
0.41	GO:0006078	(1->6)-beta-D-glucan biosynthetic process
0.37	GO:0042546	cell wall biogenesis
0.37	GO:0030036	actin cytoskeleton organization
0.37	GO:0097435	supramolecular fiber organization
0.35	GO:0071420	cellular response to histamine
0.35	GO:0035372	protein localization to microtubule

0.76	GO:0048365	Rac GTPase binding
0.73	GO:0003779	actin binding
0.35	GO:0044325	ion channel binding

0.73	GO:0055037	recycling endosome
0.73	GO:0030027	lamellipodium
0.56	GO:0005634	nucleus
0.55	GO:0005739	mitochondrion
0.35	GO:0005856	cytoskeleton
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

tr|Q0KI97|Q0KI97_DROME
GEO13368p1
Search

0.10	Formation of mitochondrial complex V assembly factor 1 homolog

0.64	GO:0006397	mRNA processing
0.62	GO:0061469	regulation of type B pancreatic cell proliferation
0.62	GO:0050995	negative regulation of lipid catabolic process

0.78	GO:0000445	THO complex part of transcription export complex
0.46	GO:0005739	mitochondrion

tr|Q0KI98|Q0KI98_DROME
FI06027p
Search

0.52	Cytoplasmic tryptophanyl-tRNA synthetase

0.78	GO:0006436	tryptophanyl-tRNA aminoacylation
0.47	GO:0048813	dendrite morphogenesis
0.38	GO:0010835	regulation of protein ADP-ribosylation
0.36	GO:0045765	regulation of angiogenesis
0.36	GO:0006469	negative regulation of protein kinase activity
0.36	GO:0031334	positive regulation of protein complex assembly
0.35	GO:0010628	positive regulation of gene expression
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.79	GO:0004830	tryptophan-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0046983	protein dimerization activity
0.37	GO:0019210	kinase inhibitor activity
0.36	GO:0019901	protein kinase binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0042802	identical protein binding
0.33	GO:0004930	G-protein coupled receptor activity

0.49	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.79

EC:6.1.1.2

GO:0004830

sp|Q0KIA2|Y9801_DROME
PP2C-like domain-containing protein CG9801
Search

0.86	Putative serine/threonine protein phosphatase signal transduction mechanism

0.36	GO:0016579	protein deubiquitination
0.36	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0006886	intracellular protein transport
0.34	GO:0016192	vesicle-mediated transport

0.36

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

0.36	GO:0008023	transcription elongation factor complex
0.35	GO:0030117	membrane coat

0.36

GO:0036459

tr|Q0KIB0|Q0KIB0_DROME
Uncharacterized protein, isoform O
Search

0.40	GO:0005515	protein binding
0.36	GO:0005549	odorant binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|Q0KIB3|Q0KIB3_DROME
CG2051, isoform A
Search

0.70	Histone acetyltransferase type B catalytic subunit

0.83	GO:0006348	chromatin silencing at telomere
0.78	GO:0016573	histone acetylation
0.51	GO:0034080	CENP-A containing nucleosome assembly
0.36	GO:0050829	defense response to Gram-negative bacterium
0.36	GO:0045089	positive regulation of innate immune response
0.34	GO:0006335	DNA replication-dependent nucleosome assembly
0.33	GO:0042176	regulation of protein catabolic process
0.33	GO:0006177	GMP biosynthetic process
0.32	GO:0050790	regulation of catalytic activity
0.32	GO:0006281	DNA repair

0.80	GO:0004402	histone acetyltransferase activity
0.79	GO:0042393	histone binding
0.33	GO:0003682	chromatin binding
0.33	GO:0003938	IMP dehydrogenase activity
0.33	GO:0030234	enzyme regulator activity
0.32	GO:0046872	metal ion binding
0.31	GO:1901265	nucleoside phosphate binding
0.31	GO:0036094	small molecule binding

0.79	GO:0000781	chromosome, telomeric region
0.61	GO:0005634	nucleus
0.39	GO:0000785	chromatin
0.38	GO:0031974	membrane-enclosed lumen
0.33	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex
0.33	GO:0031248	protein acetyltransferase complex
0.33	GO:1905369	endopeptidase complex

0.80

GO:0004402

sp|Q0KIC3|Y3427_DROME
Uncharacterized protein CG43427
Search

0.37	GO:0060079	excitatory postsynaptic potential
0.37	GO:0035235	ionotropic glutamate receptor signaling pathway
0.36	GO:0036211	protein modification process
0.35	GO:0044267	cellular protein metabolic process
0.34	GO:0034220	ion transmembrane transport

0.52	GO:0046872	metal ion binding
0.37	GO:0005234	extracellularly glutamate-gated ion channel activity
0.37	GO:0004970	ionotropic glutamate receptor activity
0.34	GO:0004077	biotin-[acetyl-CoA-carboxylase] ligase activity

0.37	GO:0045211	postsynaptic membrane
0.36	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.34

EC:6.3.4.15

GO:0004077

tr|Q0KIE7|Q0KIE7_DROME
Ankyrin, isoform B
Search

0.37

Ankyrin

0.60	GO:0007165	signal transduction
0.50	GO:0007016	cytoskeletal anchoring at plasma membrane
0.37	GO:0042157	lipoprotein metabolic process
0.37	GO:0006869	lipid transport

0.40	GO:0008092	cytoskeletal protein binding
0.37	GO:0008289	lipid binding
0.36	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.36	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.36	GO:0004623	phospholipase A2 activity

0.53	GO:0045170	spectrosome
0.43	GO:0045169	fusome
0.39	GO:0005886	plasma membrane
0.36	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.36

EC:3.1.1.4

GO:0004623

tr|Q0KIF2|Q0KIF2_DROME
Eye-enriched kainate receptor, isoform B
Search

0.70	Ionotropic glutamate receptor

0.78	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.56	GO:0016057	regulation of membrane potential in photoreceptor cell
0.56	GO:0071632	optomotor response
0.55	GO:0071484	cellular response to light intensity
0.54	GO:0035249	synaptic transmission, glutamatergic
0.46	GO:0060025	regulation of synaptic activity

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.43	GO:0099094	ligand-gated cation channel activity
0.43	GO:0005272	sodium channel activity
0.42	GO:0098782	mechanosensitived potassium channel activity

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|Q0KIG0|Q0KIG0_DROME
Uncharacterized protein
Search

0.58

GO:0006508

proteolysis

0.65

GO:0004252

serine-type endopeptidase activity

0.48

GO:0005615

extracellular space

0.65

GO:0004252

sp|Q10714|ACE_DROME
Angiotensin-converting enzyme
Search

0.74	Angiotensin-converting enzyme

0.61	GO:0006508	proteolysis
0.48	GO:0009609	response to symbiotic bacterium
0.46	GO:0007291	sperm individualization
0.46	GO:0007289	spermatid nucleus differentiation
0.44	GO:0007552	metamorphosis
0.42	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.42	GO:0030431	sleep
0.41	GO:0002027	regulation of heart rate
0.40	GO:0003007	heart morphogenesis
0.33	GO:0006351	transcription, DNA-templated

0.84	GO:0008241	peptidyl-dipeptidase activity
0.72	GO:0004180	carboxypeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.54	GO:0046872	metal ion binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.34	GO:0005515	protein binding
0.33	GO:0004175	endopeptidase activity
0.33	GO:0003677	DNA binding

0.45	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:3.4.15

GO:0008241

tr|Q107I8|Q107I8_DROME
CHKov1
Search

0.59	Hemoglobin subunit alpha-A

0.44

GO:0016310

phosphorylation

0.50

GO:0016740

transferase activity

0.30

GO:0044425

membrane part

0.50

GO:0016740

sp|Q11002|CANA_DROME
Calpain-A
Search

0.69	Calpain family cysteine protease

0.61	GO:0006508	proteolysis
0.39	GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning
0.38	GO:0008345	larval locomotory behavior
0.38	GO:0016322	neuron remodeling
0.38	GO:0007520	myoblast fusion
0.38	GO:0042335	cuticle development
0.37	GO:0008340	determination of adult lifespan
0.37	GO:0050832	defense response to fungus
0.36	GO:0051604	protein maturation

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.65	GO:0005509	calcium ion binding
0.32	GO:0016887	ATPase activity

0.45	GO:0005622	intracellular
0.37	GO:0043025	neuronal cell body
0.34	GO:0043228	non-membrane-bounded organelle

0.32

GO:0016887

tr|Q1EC10|Q1EC10_DROME
IP12271p
Search

0.34	proton-coupled folate transporter

0.55	GO:0055085	transmembrane transport
0.54	GO:0097254	renal tubular secretion
0.45	GO:0009636	response to toxic substance
0.35	GO:0007034	vacuolar transport

0.50

GO:0005215

transporter activity

0.33	GO:1990904	ribonucleoprotein complex
0.32	GO:0044424	intracellular part
0.30	GO:0016020	membrane

tr|Q1EC11|Q1EC11_DROME
IP11267p
Search

0.64	proto-oncogene serine/threonine-protein kinase mos

0.63	GO:0006468	protein phosphorylation
0.57	GO:0048599	oocyte development
0.56	GO:0007050	cell cycle arrest
0.55	GO:0032008	positive regulation of TOR signaling
0.55	GO:0043410	positive regulation of MAPK cascade
0.41	GO:1902103	negative regulation of metaphase/anaphase transition of meiotic cell cycle
0.38	GO:0007154	cell communication
0.38	GO:0009856	pollination
0.38	GO:0008037	cell recognition
0.37	GO:0023052	signaling

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004871	signal transducer activity
0.33	GO:0003725	double-stranded RNA binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0005078	MAP-kinase scaffold activity
0.32	GO:0045182	translation regulator activity

0.34	GO:0005737	cytoplasm
0.33	GO:1990315	Mcs4 RR-MAPKKK complex
0.32	GO:0005934	cellular bud tip
0.32	GO:0005935	cellular bud neck
0.32	GO:0005634	nucleus
0.32	GO:0035770	ribonucleoprotein granule
0.32	GO:0031248	protein acetyltransferase complex
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.32

EC:2.3.1.88

GO:0004596

tr|Q1EC46|Q1EC46_DROME
Tetraspanin
Search

0.40	Tetraspanin

0.45

GO:0007166

cell surface receptor signaling pathway

0.43

GO:0005887

integral component of plasma membrane

tr|Q1ECA0|Q1ECA0_DROME
IP09280p
Search

0.10	type-2 histone deacetylase 1

0.40	GO:0060255	regulation of macromolecule metabolic process
0.39	GO:0031326	regulation of cellular biosynthetic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0006397	mRNA processing
0.38	GO:0034477	U6 snRNA 3'-end processing
0.38	GO:0032501	multicellular organismal process
0.38	GO:0007018	microtubule-based movement
0.37	GO:0071456	cellular response to hypoxia
0.37	GO:0046580	negative regulation of Ras protein signal transduction

0.40	GO:0050825	ice binding
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003676	nucleic acid binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0003777	microtubule motor activity
0.37	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.37	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.37	GO:0004788	thiamine diphosphokinase activity
0.37	GO:0004107	chorismate synthase activity
0.36	GO:0016887	ATPase activity

0.40	GO:0005634	nucleus
0.38	GO:0043234	protein complex
0.37	GO:0044447	axoneme part
0.36	GO:0031248	protein acetyltransferase complex
0.36	GO:0016282	eukaryotic 43S preinitiation complex
0.36	GO:0033290	eukaryotic 48S preinitiation complex
0.36	GO:0015630	microtubule cytoskeleton
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044459	plasma membrane part
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.6.2	GO:0004788
0.37	KEGG:R01714	GO:0004107

tr|Q1ECC3|Q1ECC3_DROME
IP01956p
Search

0.30

GO:0044425

membrane part

tr|Q1JUZ1|Q1JUZ1_DROME
Neverland
Search

NVD

0.77	Rieske-domain protein Neverland

0.52	GO:0055114	oxidation-reduction process
0.45	GO:0045456	ecdysteroid biosynthetic process
0.44	GO:0002168	instar larval development
0.43	GO:0035264	multicellular organism growth
0.43	GO:0007552	metamorphosis
0.34	GO:0008203	cholesterol metabolic process

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.54	GO:0016491	oxidoreductase activity
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.33	GO:0005615	extracellular space
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

sp|Q1LZ08|WDR48_DROME
WD repeat-containing protein 48 homolog
Search

WDR48

0.63	WD repeat-containing protein 48

0.75	GO:1902525	regulation of protein monoubiquitination
0.73	GO:0072520	seminiferous tubule development
0.69	GO:0035264	multicellular organism growth
0.68	GO:0016579	protein deubiquitination
0.68	GO:0050679	positive regulation of epithelial cell proliferation
0.68	GO:0043588	skin development
0.68	GO:0007338	single fertilization
0.67	GO:0048705	skeletal system morphogenesis
0.65	GO:0007283	spermatogenesis
0.65	GO:0048568	embryonic organ development

0.46	GO:0043130	ubiquitin binding
0.44	GO:0016905	myosin heavy chain kinase activity
0.42	GO:0003924	GTPase activity
0.41	GO:0032550	purine ribonucleoside binding
0.41	GO:0019001	guanyl nucleotide binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003677	DNA binding

0.56	GO:0005634	nucleus
0.46	GO:0005770	late endosome
0.45	GO:0005764	lysosome
0.30	GO:0016020	membrane

0.44

EC:2.7.11.7

GO:0016905

tr|Q1LZ24|Q1LZ24_DROME
CG1603, isoform A
Search

LOC108094041

0.86	PR domain zinc finger protein 5 isoform X2

0.50	GO:0006351	transcription, DNA-templated
0.50	GO:1903506	regulation of nucleic acid-templated transcription
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.45	GO:0046579	positive regulation of Ras protein signal transduction
0.45	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.39	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0032259	methylation
0.33	GO:0016567	protein ubiquitination
0.33	GO:0000154	rRNA modification

0.51	GO:0003676	nucleic acid binding
0.40	GO:0003713	transcription coactivator activity
0.35	GO:0046872	metal ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0140102	catalytic activity, acting on a rRNA

0.53	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0008168

tr|Q1RKU8|Q1RKU8_DROME
IP10415p
Search

0.48	WD repeat-containing protein 5

0.59	GO:0051568	histone H3-K4 methylation
0.44	GO:0006468	protein phosphorylation
0.43	GO:0043966	histone H3 acetylation
0.41	GO:0051649	establishment of localization in cell
0.41	GO:0016458	gene silencing
0.41	GO:0016192	vesicle-mediated transport
0.41	GO:0070727	cellular macromolecule localization
0.40	GO:0060290	transdifferentiation
0.40	GO:0015031	protein transport
0.40	GO:1903341	regulation of meiotic DNA double-strand break formation

0.46	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.44	GO:0004672	protein kinase activity
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.40	GO:0043168	anion binding
0.39	GO:0008144	drug binding
0.39	GO:0005198	structural molecule activity
0.39	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0043565	sequence-specific DNA binding
0.35	GO:0043130	ubiquitin binding

0.58	GO:0035097	histone methyltransferase complex
0.44	GO:0030663	COPI-coated vesicle membrane
0.43	GO:0030117	membrane coat
0.42	GO:0000139	Golgi membrane
0.41	GO:0000123	histone acetyltransferase complex
0.39	GO:0036064	ciliary basal body
0.38	GO:0000781	chromosome, telomeric region
0.34	GO:0005730	nucleolus
0.34	GO:0072357	PTW/PP1 phosphatase complex
0.33	GO:0000922	spindle pole

0.34	EC:4.2.1.68	GO:0050023
0.34	KEGG:R03688	GO:0050023

tr|Q1RKX9|Q1RKX9_DROME
IP14890p
Search

tr|Q1RKZ2|Q1RKZ2_DROME
IP15503p2
Search

tr|Q1RL13|Q1RL13_DROME
Glutaminase, isoform H
Search

0.42	Glutaminase kidney isoform, mitochondrial

0.71	GO:0006541	glutamine metabolic process
0.36	GO:0006537	glutamate biosynthetic process
0.35	GO:0009065	glutamine family amino acid catabolic process

0.79	GO:0004359	glutaminase activity
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005739	mitochondrion
0.35	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.79

EC:3.5.1.2

GO:0004359

tr|Q1W9P9|Q1W9P9_DROME
Echinus splice form 3
Search

0.72	Echinus splice form 3

0.69	GO:0016579	protein deubiquitination
0.60	GO:0046667	compound eye retinal cell programmed cell death
0.59	GO:0046672	positive regulation of compound eye retinal cell programmed cell death
0.58	GO:0016318	ommatidial rotation
0.35	GO:0032012	regulation of ARF protein signal transduction
0.34	GO:0006457	protein folding
0.34	GO:0090286	cytoskeletal anchoring at nuclear membrane
0.34	GO:0065009	regulation of molecular function
0.34	GO:0006281	DNA repair
0.34	GO:0006857	oligopeptide transport

0.69	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.56	GO:0008157	protein phosphatase 1 binding
0.35	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.35	GO:0031072	heat shock protein binding
0.35	GO:0003684	damaged DNA binding
0.34	GO:0051082	unfolded protein binding
0.34	GO:0004519	endonuclease activity
0.34	GO:0051015	actin filament binding
0.33	GO:0046872	metal ion binding
0.32	GO:0022857	transmembrane transporter activity

0.34	GO:0005634	nucleus
0.33	GO:0012505	endomembrane system
0.33	GO:0098796	membrane protein complex
0.32	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

0.69

GO:0036459

tr|Q1WWA2|Q1WWA2_DROME
GEO11554p1
Search

tr|Q1WWB7|Q1WWB7_DROME
IP10750p
Search

GNB1L

0.58	guanine nucleotide-binding protein subunit beta-like protein 1

0.64	GO:0035176	social behavior
0.46	GO:0016310	phosphorylation
0.45	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.38	GO:0006428	isoleucyl-tRNA aminoacylation
0.38	GO:0006338	chromatin remodeling
0.37	GO:0016569	covalent chromatin modification
0.37	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.48	GO:0005515	protein binding
0.48	GO:0016301	kinase activity
0.47	GO:0005549	odorant binding
0.46	GO:0004984	olfactory receptor activity
0.38	GO:0004822	isoleucine-tRNA ligase activity
0.37	GO:0002161	aminoacyl-tRNA editing activity
0.37	GO:0000049	tRNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005737	cytoplasm
0.40	GO:0070209	ASTRA complex
0.30	GO:0016020	membrane

0.38	EC:6.1.1.5	GO:0004822
0.38	KEGG:R03656	GO:0004822

tr|Q1WWC1|Q1WWC1_DROME
IP12064p
Search

0.13	BEACH domain-containing protein lvsB

0.64	GO:0032008	positive regulation of TOR signaling
0.54	GO:0065009	regulation of molecular function

0.64	GO:0032947	protein complex scaffold activity
0.60	GO:0005085	guanyl-nucleotide exchange factor activity

sp|Q23970|PBP6_DROME
Pheromone-binding protein-related protein 6
Search

0.79	Olfactory Specific E

0.37

GO:0007608

sensory perception of smell

0.80

GO:0005549

odorant binding

0.36	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|Q23971|OSC_DROME
Antennal-specific protein OS-C
Search

sp|Q23972|SMG_DROME
Protein Smaug
Search

0.83	GO:0043488	regulation of mRNA stability
0.76	GO:0017148	negative regulation of translation
0.54	GO:2001141	regulation of RNA biosynthetic process
0.47	GO:0007275	multicellular organism development
0.42	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.42	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.39	GO:0051236	establishment of RNA localization
0.33	GO:0045727	positive regulation of translation

0.85	GO:0030371	translation repressor activity
0.59	GO:0003723	RNA binding
0.41	GO:0090079	translation regulator activity, nucleic acid binding
0.41	GO:0017022	myosin binding
0.31	GO:0008270	zinc ion binding

0.41	GO:0000932	P-body
0.34	GO:0045202	synapse
0.34	GO:0001650	fibrillar center
0.33	GO:0030054	cell junction
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q23973|MTRM_DROME
Protein matrimony
Search

0.86	GO:0032837	distributive segregation
0.85	GO:0016321	female meiosis chromosome segregation
0.81	GO:0045143	homologous chromosome segregation
0.81	GO:0007050	cell cycle arrest
0.81	GO:0051445	regulation of meiotic cell cycle
0.45	GO:0006887	exocytosis

0.45	GO:0008013	beta-catenin binding
0.40	GO:0003677	DNA binding

0.60	GO:0005634	nucleus
0.45	GO:0000145	exocyst
0.45	GO:0005694	chromosome

sp|Q23976|KU70_DROME
ATP-dependent DNA helicase 2 subunit 1
Search

IRBP

0.94	ATP-dependent DNA helicase 2 subunit 1

0.81	GO:0006303	double-strand break repair via nonhomologous end joining
0.78	GO:0000723	telomere maintenance
0.63	GO:0032392	DNA geometric change
0.36	GO:0006310	DNA recombination
0.33	GO:0016310	phosphorylation
0.33	GO:0007165	signal transduction

0.82	GO:0042162	telomeric DNA binding
0.73	GO:0003684	damaged DNA binding
0.64	GO:0004003	ATP-dependent DNA helicase activity
0.57	GO:0046982	protein heterodimerization activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016301	kinase activity

0.84	GO:0043564	Ku70:Ku80 complex
0.39	GO:0000784	nuclear chromosome, telomeric region

sp|Q23977|HEP_DROME
Dual specificity mitogen-activated protein kinase kinase hemipterous
Search

0.84	Dual specificity mitogen-activated protein kinase kinase hemipterous

0.63	GO:0006468	protein phosphorylation
0.58	GO:0031098	stress-activated protein kinase signaling cascade
0.56	GO:0046844	micropyle formation
0.56	GO:0007561	imaginal disc eversion
0.56	GO:0043406	positive regulation of MAP kinase activity
0.55	GO:0007395	dorsal closure, spreading of leading edge cells
0.55	GO:0030381	chorion-containing eggshell pattern formation
0.55	GO:0034769	basement membrane disassembly
0.55	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.54	GO:0046528	imaginal disc fusion

0.63	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0019901	protein kinase binding
0.54	GO:0005078	MAP-kinase scaffold activity
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004871	signal transducer activity
0.41	GO:0000287	magnesium ion binding
0.37	GO:0019903	protein phosphatase binding

0.50	GO:0030424	axon
0.38	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q23978|MY31D_DROME
Myosin-IA
Search

0.65	Unconventional myosin-Ih

0.74	GO:0007018	microtubule-based movement
0.50	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.49	GO:0071907	determination of digestive tract left/right asymmetry
0.47	GO:0007498	mesoderm development
0.41	GO:0010923	negative regulation of phosphatase activity
0.37	GO:0051641	cellular localization
0.36	GO:0071976	cell gliding
0.36	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.36	GO:0072678	T cell migration
0.36	GO:0002456	T cell mediated immunity

0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019904	protein domain specific binding
0.36	GO:0005516	calmodulin binding
0.36	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding

0.77	GO:0016459	myosin complex
0.45	GO:0005938	cell cortex
0.41	GO:0005903	brush border
0.40	GO:0043209	myelin sheath
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.36	GO:0001891	phagocytic cup
0.35	GO:0005902	microvillus
0.35	GO:0030175	filopodium
0.35	GO:0031256	leading edge membrane

0.34

GO:0016887

sp|Q23979|MY61F_DROME
Myosin-IB
Search

0.66	Unconventional myosin-Ih

0.74	GO:0007018	microtubule-based movement
0.42	GO:0032835	glomerulus development
0.36	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.36	GO:0071907	determination of digestive tract left/right asymmetry
0.36	GO:0032528	microvillus organization
0.35	GO:0007498	mesoderm development
0.35	GO:0042742	defense response to bacterium

0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005516	calmodulin binding
0.34	GO:0042623	ATPase activity, coupled

0.77	GO:0016459	myosin complex
0.36	GO:0031941	filamentous actin
0.35	GO:0005903	brush border
0.35	GO:0005938	cell cortex
0.34	GO:0016012	sarcoglycan complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q23982|PEB2_DROME
Ejaculatory bulb-specific protein 2
Search

EBPII

0.92	Ejaculatory bulb-specific protein 2

0.87	GO:0045434	negative regulation of female receptivity, post-mating
0.61	GO:0045297	post-mating behavior

0.51

GO:0005615

extracellular space

sp|Q23983|SNAP_DROME
Alpha-soluble NSF attachment protein
Search

0.40	Soluble nsf attachment protein (Snap)

0.69	GO:0006886	intracellular protein transport
0.51	GO:0035494	SNARE complex disassembly
0.47	GO:0048526	imaginal disc-derived wing expansion
0.46	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane
0.46	GO:0034214	protein hexamerization
0.45	GO:0007274	neuromuscular synaptic transmission
0.45	GO:0001745	compound eye morphogenesis
0.44	GO:0006891	intra-Golgi vesicle-mediated transport
0.44	GO:0000281	mitotic cytokinesis
0.43	GO:0051260	protein homooligomerization

0.51	GO:0005483	soluble NSF attachment protein activity
0.49	GO:0000149	SNARE binding
0.35	GO:0001671	ATPase activator activity
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004871	signal transducer activity

0.45	GO:0005622	intracellular
0.45	GO:0043195	terminal bouton
0.41	GO:0031982	vesicle
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.38	GO:0098796	membrane protein complex
0.37	GO:0043209	myelin sheath
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

sp|Q23985|DTX_DROME
Protein deltex
Search

0.69	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.67	GO:0007220	Notch receptor processing
0.65	GO:0045746	negative regulation of Notch signaling pathway
0.65	GO:0045747	positive regulation of Notch signaling pathway
0.64	GO:0035220	wing disc development
0.62	GO:0007219	Notch signaling pathway
0.57	GO:0016567	protein ubiquitination
0.56	GO:0006897	endocytosis
0.35	GO:0060255	regulation of macromolecule metabolic process
0.34	GO:0031326	regulation of cellular biosynthetic process

0.66	GO:0005112	Notch binding
0.61	GO:0008270	zinc ion binding
0.59	GO:0061630	ubiquitin protein ligase activity
0.41	GO:0017124	SH3 domain binding
0.35	GO:0003676	nucleic acid binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0016874	ligase activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0031151	histone methyltransferase activity (H3-K79 specific)

0.42	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.34	GO:0031461	cullin-RING ubiquitin ligase complex
0.33	GO:0005815	microtubule organizing center
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0043234	protein complex
0.33	GO:0032433	filopodium tip
0.32	GO:0000785	chromatin
0.32	GO:0045178	basal part of cell
0.32	GO:0045177	apical part of cell

0.34

GO:0004725

sp|Q23989|QUAI_DROME
Villin-like protein quail
Search

0.97	Villin-like protein quail

0.86	GO:0007300	ovarian nurse cell to oocyte transport
0.75	GO:0007015	actin filament organization
0.40	GO:0035317	imaginal disc-derived wing hair organization
0.39	GO:0051693	actin filament capping

0.78	GO:0051015	actin filament binding
0.37	GO:0005509	calcium ion binding

0.39	GO:0005884	actin filament
0.33	GO:0005737	cytoplasm

sp|Q23997|C5210_DROME
Chitinase-like protein CG5210
Search

0.33	Imaginal disc growth factor

0.60	GO:0040003	chitin-based cuticle development
0.60	GO:0018990	ecdysis, chitin-based cuticle
0.60	GO:0005975	carbohydrate metabolic process
0.56	GO:0042060	wound healing
0.56	GO:0007444	imaginal disc development
0.42	GO:0008284	positive regulation of cell proliferation
0.42	GO:0043066	negative regulation of apoptotic process
0.40	GO:0006032	chitin catabolic process
0.36	GO:0006034	cuticle chitin metabolic process

0.76	GO:0008061	chitin binding
0.62	GO:0008084	imaginal disc growth factor receptor binding
0.56	GO:0004568	chitinase activity

0.47	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.56

EC:3.2.1.14

GO:0004568

sp|Q24008|INAD_DROME
Inactivation-no-after-potential D protein
Search

INAD

0.63	Inactivation no afterpotential D, isoform B

0.81	GO:0016059	deactivation of rhodopsin mediated signaling
0.77	GO:0050962	detection of light stimulus involved in sensory perception
0.72	GO:0007605	sensory perception of sound
0.71	GO:0071482	cellular response to light stimulus
0.70	GO:0007602	phototransduction
0.69	GO:0007601	visual perception
0.58	GO:0008104	protein localization
0.39	GO:0030001	metal ion transport
0.37	GO:0046916	cellular transition metal ion homeostasis
0.34	GO:0055114	oxidation-reduction process

0.86	GO:0031473	myosin III binding
0.76	GO:0030159	receptor signaling complex scaffold activity
0.70	GO:0009881	photoreceptor activity
0.70	GO:0005516	calmodulin binding
0.37	GO:0046872	metal ion binding
0.34	GO:0016491	oxidoreductase activity

0.81	GO:0016027	inaD signaling complex
0.42	GO:0005923	bicellular tight junction
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0016491

sp|Q24009|BICC_DROME
Protein bicaudal C
Search

0.53	Bicaudal-c

0.50	GO:0000226	microtubule cytoskeleton organization
0.49	GO:0030036	actin cytoskeleton organization
0.45	GO:0008104	protein localization
0.45	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.44	GO:0007368	determination of left/right symmetry
0.43	GO:0007507	heart development
0.39	GO:0007319	negative regulation of oskar mRNA translation
0.38	GO:0007297	ovarian follicle cell migration
0.36	GO:0000278	mitotic cell cycle
0.33	GO:0018108	peptidyl-tyrosine phosphorylation

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.33	GO:0004713	protein tyrosine kinase activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.31	GO:0003924	GTPase activity
0.31	GO:0032550	purine ribonucleoside binding
0.31	GO:0019001	guanyl nucleotide binding

0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0004713

sp|Q24020|FLII_DROME
Protein flightless-1
Search

0.73	Flightless-1

0.84	GO:0051014	actin filament severing
0.74	GO:0030036	actin cytoskeleton organization
0.56	GO:0007527	adult somatic muscle development
0.55	GO:0001703	gastrulation with mouth forming first
0.52	GO:0055002	striated muscle cell development
0.51	GO:0010927	cellular component assembly involved in morphogenesis
0.48	GO:0097435	supramolecular fiber organization
0.47	GO:0070925	organelle assembly
0.35	GO:0006470	protein dephosphorylation
0.33	GO:0006886	intracellular protein transport

0.78	GO:0051015	actin filament binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0004721	phosphoprotein phosphatase activity

0.33	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004721

sp|Q24025|SOG_DROME
Dorsal-ventral patterning protein Sog
Search

SOG

0.74	Dorsal-ventral patterning protein Sog

0.69	GO:0007275	multicellular organism development
0.57	GO:0008293	torso signaling pathway
0.55	GO:0007308	oocyte construction
0.51	GO:0002009	morphogenesis of an epithelium
0.39	GO:0007398	ectoderm development
0.39	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.38	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.38	GO:0030509	BMP signaling pathway
0.38	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.38	GO:0030510	regulation of BMP signaling pathway

0.53	GO:0005518	collagen binding
0.37	GO:0008083	growth factor activity
0.31	GO:0003676	nucleic acid binding

0.37	GO:0000139	Golgi membrane
0.36	GO:0005576	extracellular region
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q24039|BRO_DROME
Protein brother
Search

BGB

0.93	Transcription factor CBF beta subunit

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:0035206	regulation of hemocyte proliferation
0.45	GO:0030097	hemopoiesis
0.44	GO:0048468	cell development
0.43	GO:0001649	osteoblast differentiation
0.42	GO:0000209	protein polyubiquitination
0.42	GO:0046649	lymphocyte activation
0.42	GO:0021700	developmental maturation
0.41	GO:0060047	heart contraction
0.40	GO:0031032	actomyosin structure organization

0.79	GO:0003713	transcription coactivator activity
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.36	GO:0003677	DNA binding
0.36	GO:0008134	transcription factor binding
0.33	GO:0008378	galactosyltransferase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.41	GO:0030018	Z disc
0.39	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

0.33

GO:0008378

sp|Q24040|BGB_DROME
Protein big brother
Search

BGB

0.90	Transcription factor CBF beta subunit

0.57	GO:2001141	regulation of RNA biosynthetic process
0.48	GO:0035206	regulation of hemocyte proliferation
0.43	GO:0048769	sarcomerogenesis
0.41	GO:0045214	sarcomere organization
0.41	GO:0060047	heart contraction
0.40	GO:0030097	hemopoiesis
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.34	GO:0048749	compound eye development
0.34	GO:0001649	osteoblast differentiation

0.79	GO:0003713	transcription coactivator activity
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.35	GO:0008134	transcription factor binding
0.35	GO:0003677	DNA binding
0.33	GO:0008378	galactosyltransferase activity

0.61	GO:0005634	nucleus
0.41	GO:0030018	Z disc
0.39	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0008378

tr|Q24044|Q24044_DROME
FI02843p
Search

CDC20

0.66	Cell division cycle 20, cofactor of APC complex

0.83	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.77	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.51	GO:0051301	cell division
0.50	GO:0007147	female meiosis II
0.49	GO:0007144	female meiosis I
0.49	GO:0060547	negative regulation of necrotic cell death
0.49	GO:0097150	neuronal stem cell population maintenance
0.48	GO:0030718	germ-line stem cell population maintenance
0.48	GO:0031915	positive regulation of synaptic plasticity
0.48	GO:0090129	positive regulation of synapse maturation

0.84	GO:0097027	ubiquitin-protein transferase activator activity
0.83	GO:0010997	anaphase-promoting complex binding
0.47	GO:0008022	protein C-terminus binding
0.45	GO:0061630	ubiquitin protein ligase activity
0.43	GO:0019899	enzyme binding
0.34	GO:0004402	histone acetyltransferase activity
0.33	GO:0004896	cytokine receptor activity
0.33	GO:0043531	ADP binding
0.33	GO:0003743	translation initiation factor activity

0.52	GO:0005680	anaphase-promoting complex
0.46	GO:0005813	centrosome
0.46	GO:0005819	spindle
0.46	GO:0000776	kinetochore
0.43	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0004402

sp|Q24046|ATPB1_DROME
Sodium/potassium-transporting ATPase subunit beta-1
Search

0.64	Sodium/potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.54	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.50	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.45	GO:0035158	regulation of tube diameter, open tracheal system
0.45	GO:0060857	establishment of glial blood-brain barrier
0.45	GO:0061343	cell adhesion involved in heart morphogenesis
0.44	GO:0019991	septate junction assembly
0.43	GO:0098655	cation transmembrane transport
0.42	GO:0007605	sensory perception of sound

0.54	GO:0005391	sodium:potassium-exchanging ATPase activity
0.34	GO:0005515	protein binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.44	GO:0005918	septate junction
0.42	GO:0030424	axon

0.54

EC:3.6.3.9

GO:0005391

sp|Q24048|ATPB2_DROME
Sodium/potassium-transporting ATPase subunit beta-2
Search

0.66	Sodium/potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.50	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.49	GO:0035158	regulation of tube diameter, open tracheal system
0.49	GO:0060857	establishment of glial blood-brain barrier
0.49	GO:0061343	cell adhesion involved in heart morphogenesis
0.49	GO:0019991	septate junction assembly
0.46	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.46	GO:0007605	sensory perception of sound
0.40	GO:0098655	cation transmembrane transport

0.50	GO:0005391	sodium:potassium-exchanging ATPase activity
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0005515	protein binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.48	GO:0005918	septate junction
0.46	GO:0030424	axon

0.50	EC:3.6.3.9	GO:0005391
0.34	KEGG:R05982 KEGG:R06722	GO:0004571

sp|Q24049|AMN_DROME
Amnesiac neuropeptides
Search

0.93	LOW QUALITY PROTEIN: amnesiac neuropeptides

0.72	GO:0042066	perineurial glial growth
0.71	GO:0007615	anesthesia-resistant memory
0.71	GO:0072375	medium-term memory
0.70	GO:0040040	thermosensory behavior
0.70	GO:0008355	olfactory learning
0.70	GO:0048266	behavioral response to pain
0.69	GO:0007190	activation of adenylate cyclase activity
0.68	GO:0008049	male courtship behavior
0.68	GO:0048149	behavioral response to ethanol
0.68	GO:0007218	neuropeptide signaling pathway

0.66	GO:0005184	neuropeptide hormone activity
0.63	GO:0001664	G-protein coupled receptor binding

0.59	GO:0005615	extracellular space
0.40	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|Q24050|Q24050_DROME
Anon-i1 protein
Search

0.51	elongator complex protein 5

0.77	GO:0002098	tRNA wobble uridine modification
0.35	GO:0016310	phosphorylation
0.35	GO:0030335	positive regulation of cell migration
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.35

GO:0016301

kinase activity

0.82	GO:0033588	Elongator holoenzyme complex
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

tr|Q24062|Q24062_DROME
Black, isoform A
Search

0.40	cysteine sulfinic acid decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.51	GO:0007632	visual behavior
0.42	GO:0045213	neurotransmitter receptor metabolic process
0.42	GO:0008355	olfactory learning
0.42	GO:0008345	larval locomotory behavior
0.41	GO:0042136	neurotransmitter biosynthetic process
0.41	GO:0007528	neuromuscular junction development
0.41	GO:0007416	synapse assembly
0.40	GO:0009612	response to mechanical stimulus
0.39	GO:1901565	organonitrogen compound catabolic process

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.35	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0017048	Rho GTPase binding
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding

0.34	GO:0000786	nucleosome
0.33	GO:0005634	nucleus
0.33	GO:0005829	cytosol

0.68

EC:4.1.1

GO:0016831

tr|Q24077|Q24077_DROME
Eig71Ej
Search

0.83	GO:0007552	metamorphosis
0.58	GO:0042742	defense response to bacterium

0.51

GO:0005576

extracellular region

sp|Q24087|XPF_DROME
DNA repair endonuclease XPF
Search

ERCC4

0.85	Excision repair cross-complementing rodent repair deficiency, complementation group 4

0.63	GO:0000712	resolution of meiotic recombination intermediates
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.62	GO:0016321	female meiosis chromosome segregation
0.62	GO:0030716	oocyte fate determination
0.61	GO:0006281	DNA repair
0.51	GO:1905768	negative regulation of double-stranded telomeric DNA binding
0.50	GO:0061819	telomeric DNA-containing double minutes formation
0.50	GO:1905765	negative regulation of protection from non-homologous end joining at telomere
0.48	GO:1904357	negative regulation of telomere maintenance via telomere lengthening
0.47	GO:0034644	cellular response to UV

0.66	GO:0003697	single-stranded DNA binding
0.65	GO:0004520	endodeoxyribonuclease activity
0.54	GO:0046982	protein heterodimerization activity
0.48	GO:0047485	protein N-terminus binding
0.47	GO:0008022	protein C-terminus binding
0.46	GO:0001094	TFIID-class transcription factor binding
0.46	GO:0003684	damaged DNA binding
0.44	GO:0042802	identical protein binding

0.52	GO:0000110	nucleotide-excision repair factor 1 complex
0.49	GO:0070522	ERCC4-ERCC1 complex
0.47	GO:0000784	nuclear chromosome, telomeric region
0.43	GO:0005669	transcription factor TFIID complex
0.30	GO:0016020	membrane

tr|Q24090|Q24090_DROME
GH08712p
Search

0.88	Swi snf-related matrix-associated actin-dependent regulator

0.78	GO:0006338	chromatin remodeling
0.47	GO:0070983	dendrite guidance
0.47	GO:0043697	cell dedifferentiation
0.47	GO:0007406	negative regulation of neuroblast proliferation
0.47	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.47	GO:0007474	imaginal disc-derived wing vein specification
0.47	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.47	GO:0097150	neuronal stem cell population maintenance
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0006357	regulation of transcription by RNA polymerase II

0.49	GO:0070984	SET domain binding
0.48	GO:0030957	Tat protein binding
0.34	GO:0001164	RNA polymerase I CORE element sequence-specific DNA binding
0.34	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.34	GO:0031492	nucleosomal DNA binding
0.34	GO:0002039	p53 binding
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003713	transcription coactivator activity

0.73	GO:0000228	nuclear chromosome
0.42	GO:0000785	chromatin
0.41	GO:1904949	ATPase complex
0.35	GO:0001741	XY body
0.34	GO:0097458	neuron part
0.33	GO:0005730	nucleolus
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q24093|ABHD2_DROME
Abhydrolase domain-containing protein 2
Search

0.31	Abhydrolase domain-containing protein 2

0.47	GO:0046464	acylglycerol catabolic process
0.47	GO:0048240	sperm capacitation
0.45	GO:0043401	steroid hormone mediated signaling pathway
0.44	GO:0032570	response to progesterone
0.44	GO:0007340	acrosome reaction
0.43	GO:0030336	negative regulation of cell migration
0.42	GO:0009611	response to wounding
0.34	GO:0022900	electron transport chain
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.52	GO:0016298	lipase activity
0.43	GO:0042562	hormone binding
0.42	GO:0052689	carboxylic ester hydrolase activity
0.42	GO:0003707	steroid hormone receptor activity
0.35	GO:0008121	ubiquinol-cytochrome-c reductase activity
0.35	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0003677	DNA binding

0.48	GO:0097524	sperm plasma membrane
0.46	GO:0036126	sperm flagellum
0.43	GO:0001669	acrosomal vesicle
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.52	EC:3.1.1	GO:0016298
0.42	KEGG:R00630	GO:0052689

sp|Q24106|HID_DROME
Cell death protein hid
Search

HID

0.96	Cell death protein hid

0.84	GO:2000685	positive regulation of cellular response to X-ray
0.84	GO:2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.83	GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death
0.83	GO:0048800	antennal morphogenesis
0.81	GO:0035096	larval midgut cell programmed cell death
0.81	GO:0008258	head involution
0.80	GO:0010114	response to red light
0.80	GO:0043153	entrainment of circadian clock by photoperiod
0.79	GO:0071480	cellular response to gamma radiation
0.77	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage

0.85	GO:1990525	BIR domain binding
0.72	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0030983	mismatched DNA binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.33	GO:0101005	ubiquitinyl hydrolase activity

0.56	GO:0005739	mitochondrion
0.36	GO:0032300	mismatch repair complex
0.30	GO:0016020	membrane

tr|Q24113|Q24113_DROME
FI21126p1
Search

NONA

0.84	Splicing factor proline-and glutamine-rich

0.43	GO:0045433	male courtship behavior, veined wing generated song production
0.41	GO:0000398	mRNA splicing, via spliceosome
0.41	GO:0007601	visual perception
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0051028	mRNA transport
0.34	GO:0006405	RNA export from nucleus
0.33	GO:0050896	response to stimulus

0.58	GO:0003723	RNA binding
0.38	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.31	GO:0032550	purine ribonucleoside binding
0.31	GO:0019001	guanyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005681	spliceosomal complex
0.34	GO:0005856	cytoskeleton
0.32	GO:0005737	cytoplasm
0.32	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q24114|DALY_DROME
Division abnormally delayed protein
Search

0.82	Division abnormally delayed, isoform B

0.86	GO:0008101	decapentaplegic signaling pathway
0.77	GO:0016055	Wnt signaling pathway
0.71	GO:2001261	negative regulation of semaphorin-plexin signaling pathway
0.67	GO:0048132	female germ-line stem cell asymmetric division
0.67	GO:0008052	sensory organ boundary specification
0.66	GO:0045570	regulation of imaginal disc growth
0.66	GO:0048085	adult chitin-containing cuticle pigmentation
0.66	GO:0008407	chaeta morphogenesis
0.66	GO:0007367	segment polarity determination
0.66	GO:0048190	wing disc dorsal/ventral pattern formation

0.38	GO:0005515	protein binding
0.35	GO:1901681	sulfur compound binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0043168	anion binding
0.32	GO:0005509	calcium ion binding

0.82	GO:0046658	anchored component of plasma membrane
0.75	GO:0005578	proteinaceous extracellular matrix
0.57	GO:0009986	cell surface
0.43	GO:0098595	perivitelline space
0.30	GO:0016021	integral component of membrane

sp|Q24117|DYL1_DROME
Dynein light chain 1, cytoplasmic
Search

0.66	Dynein light chain cytoplasmic

0.72	GO:0007017	microtubule-based process
0.47	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.47	GO:2000576	positive regulation of microtubule motor activity
0.45	GO:0030705	cytoskeleton-dependent intracellular transport
0.45	GO:0060271	cilium assembly
0.44	GO:0032781	positive regulation of ATPase activity
0.41	GO:0006928	movement of cell or subcellular component
0.37	GO:1904801	positive regulation of neuron remodeling
0.37	GO:0007290	spermatid nucleus elongation
0.37	GO:0035071	salivary gland cell autophagic cell death

0.47	GO:0045505	dynein intermediate chain binding
0.46	GO:0051959	dynein light intermediate chain binding
0.46	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.42	GO:0008092	cytoskeletal protein binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0097718	disordered domain specific binding
0.36	GO:0097110	scaffold protein binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0008022	protein C-terminus binding

0.79	GO:0030286	dynein complex
0.45	GO:0031475	myosin V complex
0.43	GO:0005815	microtubule organizing center
0.38	GO:0005874	microtubule
0.36	GO:0005929	cilium
0.35	GO:0008180	COP9 signalosome
0.35	GO:0072686	mitotic spindle
0.35	GO:0000776	kinetochore
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0044444	cytoplasmic part

0.46

EC:3.6.4.4

GO:0008574

sp|Q24118|PIGE_DROME
Protein pigeon
Search

0.96	Pigeon protein (linotte protein)

0.37	GO:0001731	formation of translation preinitiation complex
0.36	GO:0006446	regulation of translational initiation

0.36

GO:0003743

translation initiation factor activity

0.37	GO:0016282	eukaryotic 43S preinitiation complex
0.37	GO:0033290	eukaryotic 48S preinitiation complex
0.36	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0016020	membrane

sp|Q24119|TRH_DROME
Protein trachealess
Search

TRH

0.77	Trachealess, isoform D

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0007425	epithelial cell fate determination, open tracheal system
0.54	GO:0035277	spiracle morphogenesis, open tracheal system
0.53	GO:0007443	Malpighian tubule morphogenesis
0.52	GO:0007435	salivary gland morphogenesis
0.51	GO:0072175	epithelial tube formation
0.51	GO:0060173	limb development

0.68	GO:0046983	protein dimerization activity
0.53	GO:0003677	DNA binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.31	GO:0005829	cytosol
0.31	GO:0043233	organelle lumen
0.31	GO:0044446	intracellular organelle part

sp|Q24120|CAPU_DROME
Protein cappuccino
Search

CAPU

0.96	Cappuccino, isoform E

0.79	GO:0045010	actin nucleation
0.60	GO:0007316	pole plasm RNA localization
0.38	GO:0060811	intracellular mRNA localization involved in anterior/posterior axis specification
0.38	GO:0007304	chorion-containing eggshell formation
0.35	GO:0015031	protein transport
0.32	GO:0007049	cell cycle

0.73	GO:0008017	microtubule binding
0.37	GO:0003779	actin binding
0.33	GO:0017048	Rho GTPase binding

0.81	GO:0005884	actin filament
0.53	GO:0005938	cell cortex
0.37	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q24133|DNAJ1_DROME
DnaJ protein homolog 1
Search

0.64	Heat shock protein 40

0.69	GO:0006457	protein folding
0.48	GO:0009408	response to heat
0.33	GO:0045892	negative regulation of transcription, DNA-templated

0.71

GO:0051082

unfolded protein binding

0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q24134|NELFD_DROME
Negative elongation factor D
Search

0.91	Negative elongation factor D

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.57	GO:0006414	translational elongation
0.46	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter
0.34	GO:0050434	positive regulation of viral transcription
0.33	GO:0006457	protein folding
0.33	GO:0006413	translational initiation

0.57	GO:0003746	translation elongation factor activity
0.34	GO:0005515	protein binding
0.33	GO:0003743	translation initiation factor activity

0.61	GO:0005634	nucleus
0.48	GO:0005703	polytene chromosome puff
0.48	GO:0005705	polytene chromosome interband
0.46	GO:0017053	transcriptional repressor complex
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q24139|COMM_DROME
Protein commissureless 1
Search

0.94	Commissureless, isoform B

0.81	GO:0007411	axon guidance
0.72	GO:0090160	Golgi to lysosome transport
0.72	GO:0070983	dendrite guidance
0.70	GO:0002092	positive regulation of receptor internalization
0.69	GO:0031623	receptor internalization
0.68	GO:0008038	neuron recognition
0.67	GO:0007416	synapse assembly
0.67	GO:0050773	regulation of dendrite development

0.73	GO:0048495	Roundabout binding
0.70	GO:0050699	WW domain binding

0.66	GO:0031902	late endosome membrane
0.65	GO:0005765	lysosomal membrane
0.65	GO:0030139	endocytic vesicle
0.58	GO:0005794	Golgi apparatus
0.56	GO:0005829	cytosol
0.47	GO:0005886	plasma membrane
0.42	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|Q24141|SGO1_DROME
Shugoshin
Search

MEI-S332

0.84

Shugoshin

0.85	GO:0007065	male meiosis sister chromatid cohesion
0.78	GO:0007143	female meiotic nuclear division
0.45	GO:0007275	multicellular organism development
0.44	GO:0051301	cell division

0.77	GO:0000775	chromosome, centromeric region
0.74	GO:0000792	heterochromatin
0.72	GO:0000794	condensed nuclear chromosome
0.67	GO:0044454	nuclear chromosome part

sp|Q24142|HR78_DROME
Nuclear hormone receptor HR78
Search

0.88	Nuclear hormone receptor HR78

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:0035002	liquid clearance, open tracheal system
0.56	GO:0010468	regulation of gene expression
0.52	GO:0030522	intracellular receptor signaling pathway
0.39	GO:0050829	defense response to Gram-negative bacterium
0.39	GO:0045089	positive regulation of innate immune response
0.34	GO:0006468	protein phosphorylation

0.75	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q24143|HR96_DROME
Nuclear hormone receptor HR96
Search

0.84	Nuclear hormone receptor HR96

0.75	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0070873	regulation of glycogen metabolic process
0.59	GO:0070328	triglyceride homeostasis
0.58	GO:0042632	cholesterol homeostasis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0042594	response to starvation
0.48	GO:0030522	intracellular receptor signaling pathway

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003707	steroid hormone receptor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.33	GO:0003993	acid phosphatase activity

0.61

GO:0005634

nucleus

0.33

EC:3.1.3.2

GO:0003993

sp|Q24145|SHARK_DROME
Tyrosine-protein kinase shark
Search

0.56	Tyrosine-protein kinase shark

0.74	GO:0007394	dorsal closure, elongation of leading edge cells
0.71	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.71	GO:0046843	dorsal appendage formation
0.70	GO:0043277	apoptotic cell clearance
0.69	GO:0018108	peptidyl-tyrosine phosphorylation
0.69	GO:0007254	JNK cascade
0.65	GO:0046777	protein autophosphorylation
0.64	GO:0045087	innate immune response
0.63	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.63	GO:0016477	cell migration

0.69	GO:0004713	protein tyrosine kinase activity
0.59	GO:0005102	receptor binding
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.62	GO:0005938	cell cortex

0.69

GO:0004713

sp|Q24151|STAT_DROME
Signal transducer and transcription activator
Search

0.69	Signal transducer and activator of transcription

0.64	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.38	GO:0035171	lamellocyte differentiation
0.38	GO:0007425	epithelial cell fate determination, open tracheal system
0.38	GO:0035172	hemocyte proliferation
0.38	GO:0008348	negative regulation of antimicrobial humoral response
0.38	GO:0030720	oocyte localization involved in germarium-derived egg chamber formation
0.38	GO:0030713	ovarian follicle cell stalk formation
0.38	GO:0007538	primary sex determination

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.36	GO:0042393	histone binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.38	GO:0098592	cytoplasmic side of apical plasma membrane
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|Q24152|CKS1_DROME
Cyclin-dependent kinases regulatory subunit
Search

0.67	Cyclin-dependent kinases regulatory subunit

0.76	GO:0045859	regulation of protein kinase activity
0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.51	GO:0016310	phosphorylation
0.47	GO:0000280	nuclear division
0.46	GO:0045787	positive regulation of cell cycle
0.45	GO:0022414	reproductive process
0.45	GO:0033674	positive regulation of kinase activity
0.45	GO:0001934	positive regulation of protein phosphorylation
0.45	GO:0007488	histoblast morphogenesis

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.52	GO:0016301	kinase activity
0.47	GO:0043539	protein serine/threonine kinase activator activity
0.46	GO:0043130	ubiquitin binding
0.46	GO:0042393	histone binding
0.45	GO:0019901	protein kinase binding
0.43	GO:0003682	chromatin binding

0.48	GO:0019005	SCF ubiquitin ligase complex
0.47	GO:0000307	cyclin-dependent protein kinase holoenzyme complex

0.82

GO:0016538

sp|Q24154|RL29_DROME
60S ribosomal protein L29
Search

0.70	60S ribosomal protein L29

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0003682	chromatin binding

0.61	GO:0005840	ribosome
0.41	GO:0044445	cytosolic part
0.37	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q24155|TRUNK_DROME
Protein trunk
Search

0.13

Trunk

0.86	GO:0007362	terminal region determination
0.86	GO:0008293	torso signaling pathway
0.49	GO:0008358	maternal determination of anterior/posterior axis, embryo

0.54

GO:0005122

torso binding

0.42	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q24157|BRN_DROME
Beta-1,3-galactosyltransferase brn
Search

0.48	Beta-1,3-galactosyltransferase brn

0.75	GO:0042248	maintenance of polarity of follicular epithelium
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.74	GO:0001744	optic lobe placode formation
0.73	GO:0007299	ovarian follicle cell-cell adhesion
0.69	GO:0006688	glycosphingolipid biosynthetic process
0.68	GO:0007293	germarium-derived egg chamber formation
0.68	GO:0007298	border follicle cell migration
0.65	GO:0007219	Notch signaling pathway
0.60	GO:0036211	protein modification process

0.81	GO:0008378	galactosyltransferase activity
0.76	GO:0046981	beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity

0.72	GO:0005794	Golgi apparatus
0.57	GO:0098588	bounding membrane of organelle
0.55	GO:0031984	organelle subcompartment
0.54	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.81

GO:0008378

sp|Q24167|SIMA_DROME
Protein similar
Search

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0071456	cellular response to hypoxia
0.45	GO:0060541	respiratory system development
0.44	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.44	GO:0048468	cell development

0.68	GO:0046983	protein dimerization activity
0.48	GO:0003700	DNA binding transcription factor activity
0.48	GO:0003677	DNA binding
0.43	GO:0035035	histone acetyltransferase binding
0.40	GO:0008134	transcription factor binding
0.36	GO:0051879	Hsp90 protein binding
0.36	GO:0002039	p53 binding
0.36	GO:0042826	histone deacetylase binding
0.35	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0051427	hormone receptor binding

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.40	GO:0005737	cytoplasm
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0033267	axon part
0.35	GO:0031514	motile cilium
0.30	GO:0016020	membrane

0.32

EC:6.4.1.2

GO:0003989

sp|Q24168|ORC2_DROME
Origin recognition complex subunit 2
Search

ORC2

0.72	Origin recognition complex subunit

0.66	GO:0006260	DNA replication
0.55	GO:0007307	eggshell chorion gene amplification
0.51	GO:0007052	mitotic spindle organization
0.51	GO:0007076	mitotic chromosome condensation
0.50	GO:0008283	cell proliferation
0.32	GO:0055114	oxidation-reduction process

0.49	GO:0003682	chromatin binding
0.44	GO:0003688	DNA replication origin binding
0.34	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.82	GO:0000808	origin recognition complex
0.61	GO:0005634	nucleus
0.57	GO:0005723	alpha-heterochromatin
0.48	GO:0031974	membrane-enclosed lumen
0.42	GO:0000939	condensed chromosome inner kinetochore
0.40	GO:0000781	chromosome, telomeric region
0.40	GO:0005813	centrosome
0.30	GO:0016020	membrane

0.32

GO:0016491

sp|Q24169|ORC5_DROME
Origin recognition complex subunit 5
Search

ORC5

0.67	Origin recognition complex subunit 5

0.66	GO:0006260	DNA replication
0.56	GO:0007052	mitotic spindle organization
0.56	GO:0007076	mitotic chromosome condensation
0.34	GO:0000055	ribosomal large subunit export from nucleus
0.34	GO:0042273	ribosomal large subunit biogenesis
0.33	GO:0030036	actin cytoskeleton organization
0.33	GO:0006355	regulation of transcription, DNA-templated

0.40	GO:0003688	DNA replication origin binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.82	GO:0000808	origin recognition complex
0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q24171|Q24171_DROME
AT08303p
Search

KSR

0.76	Kinase suppressor of ras

0.67	GO:0007426	tracheal outgrowth, open tracheal system
0.63	GO:0007476	imaginal disc-derived wing morphogenesis
0.63	GO:0006468	protein phosphorylation
0.62	GO:0007265	Ras protein signal transduction
0.54	GO:0008293	torso signaling pathway
0.52	GO:0007351	tripartite regional subdivision
0.52	GO:0046579	positive regulation of Ras protein signal transduction
0.52	GO:0000578	embryonic axis specification
0.51	GO:0009948	anterior/posterior axis specification
0.51	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0046872	metal ion binding
0.37	GO:0004871	signal transducer activity
0.34	GO:0030246	carbohydrate binding
0.33	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.44	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane

0.66

GO:0004674

tr|Q24173|Q24173_DROME
Beta subunit of type I geranylgeranyl transferase, isoform A
Search

0.78	Geranylgeranyl transferase beta-subunit type I

0.53	GO:0072359	circulatory system development
0.51	GO:0018344	protein geranylgeranylation
0.51	GO:0048568	embryonic organ development
0.50	GO:0035295	tube development
0.49	GO:0060429	epithelium development
0.43	GO:0071695	anatomical structure maturation
0.40	GO:0046579	positive regulation of Ras protein signal transduction
0.40	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.37	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
0.36	GO:0045787	positive regulation of cell cycle

0.53	GO:0004661	protein geranylgeranyltransferase activity
0.36	GO:0019840	isoprenoid binding
0.36	GO:0042277	peptide binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0008144	drug binding
0.33	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.53	GO:0005953	CAAX-protein geranylgeranyltransferase complex
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.53

EC:2.5.1

GO:0004661

sp|Q24174|ABRU_DROME
Protein abrupt
Search

0.32	Abrupt, isoform B

0.63	GO:0044719	regulation of imaginal disc-derived wing size
0.62	GO:0008039	synaptic target recognition
0.62	GO:0016203	muscle attachment
0.62	GO:0016319	mushroom body development
0.61	GO:0007298	border follicle cell migration
0.60	GO:0048813	dendrite morphogenesis
0.56	GO:0007423	sensory organ development
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0016198	axon choice point recognition
0.35	GO:0006351	transcription, DNA-templated

0.50	GO:0003676	nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0046872	metal ion binding

0.47	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q24175|Q24175_DROME
Discontinuous actin hexagon
Search

DAH

0.73	Discontinuous actin hexagon

0.48	GO:0007349	cellularization
0.47	GO:0044837	actomyosin contractile ring organization
0.47	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.34	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0065009	regulation of molecular function
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0006468	protein phosphorylation
0.33	GO:0007041	lysosomal transport
0.32	GO:0071985	multivesicular body sorting pathway

0.63	GO:0008270	zinc ion binding
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0003779	actin binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0051219	phosphoprotein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004872	receptor activity

0.44	GO:0019898	extrinsic component of membrane
0.32	GO:0000814	ESCRT II complex

sp|Q24178|PSA72_DROME
Proteasome subunit alpha type-7-1A
Search

0.48	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.71	GO:0043632	modification-dependent macromolecule catabolic process
0.35	GO:0008063	Toll signaling pathway
0.34	GO:0007623	circadian rhythm

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.60	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|Q24179|SLY1_DROME
Protein sly1 homolog
Search

0.74	Vesicle protein sorting-associated

0.80	GO:0006904	vesicle docking involved in exocytosis
0.48	GO:0048190	wing disc dorsal/ventral pattern formation
0.45	GO:0009653	anatomical structure morphogenesis
0.43	GO:0048869	cellular developmental process
0.42	GO:0034436	glycoprotein transport
0.42	GO:1902902	negative regulation of autophagosome assembly
0.41	GO:0031101	fin regeneration
0.40	GO:0048193	Golgi vesicle transport
0.40	GO:1904888	cranial skeletal system development
0.40	GO:0051216	cartilage development

0.37	GO:0019905	syntaxin binding
0.36	GO:0030580	quinone cofactor methyltransferase activity
0.36	GO:0003735	structural constituent of ribosome
0.35	GO:0047485	protein N-terminus binding
0.34	GO:0004395	hexaprenyldihydroxybenzoate methyltransferase activity
0.34	GO:0008689	3-demethylubiquinone-9 3-O-methyltransferase activity
0.33	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005801	cis-Golgi network
0.39	GO:0005763	mitochondrial small ribosomal subunit
0.37	GO:0017119	Golgi transport complex
0.36	GO:0005798	Golgi-associated vesicle
0.35	GO:0032580	Golgi cisterna membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005886	plasma membrane
0.33	GO:0031314	extrinsic component of mitochondrial inner membrane
0.33	GO:0098533	ATPase dependent transmembrane transport complex
0.33	GO:0098796	membrane protein complex

0.34

EC:2.1.1.114

GO:0004395

sp|Q24180|DEAF1_DROME
Deformed epidermal autoregulatory factor 1
Search

DEAF1

0.85	Deformed epidermal autoregulatory factor 1

0.55	GO:0009792	embryo development ending in birth or egg hatching
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0050776	regulation of immune response
0.48	GO:0033599	regulation of mammary gland epithelial cell proliferation
0.47	GO:0001662	behavioral fear response
0.47	GO:0008542	visual learning
0.46	GO:0060606	tube closure
0.46	GO:0001838	embryonic epithelial tube formation
0.45	GO:0001501	skeletal system development

0.55	GO:0003677	DNA binding
0.46	GO:0003700	DNA binding transcription factor activity
0.44	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0008270	zinc ion binding
0.32	GO:0005515	protein binding

0.53	GO:0005700	polytene chromosome
0.46	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.33	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm

sp|Q24185|HOOK_DROME
Protein hook
Search

0.47	Putative golgi-associated microtubule-binding protein hook3

0.80	GO:0030705	cytoskeleton-dependent intracellular transport
0.79	GO:0008340	determination of adult lifespan
0.69	GO:0006897	endocytosis
0.50	GO:0031122	cytoplasmic microtubule organization
0.47	GO:0045467	R7 cell development
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0015031	protein transport

0.76	GO:0017137	Rab GTPase binding
0.73	GO:0008017	microtubule binding
0.51	GO:0051959	dynein light intermediate chain binding
0.38	GO:0046983	protein dimerization activity
0.35	GO:0003677	DNA binding
0.33	GO:0051019	mitogen-activated protein kinase binding
0.33	GO:0070840	dynein complex binding
0.33	GO:0005487	structural constituent of nuclear pore
0.33	GO:0031072	heat shock protein binding
0.33	GO:0003682	chromatin binding

0.74	GO:0005768	endosome
0.71	GO:0045202	synapse
0.70	GO:0005874	microtubule
0.69	GO:0030054	cell junction
0.48	GO:0005813	centrosome
0.36	GO:0005634	nucleus
0.33	GO:0016234	inclusion body
0.33	GO:0005868	cytoplasmic dynein complex
0.33	GO:0072686	mitotic spindle
0.33	GO:0000776	kinetochore

sp|Q24186|RS5A_DROME
40S ribosomal protein S5a
Search

RPS5

0.42	Ribosomal protein S5 isoform A

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.44	GO:0000028	ribosomal small subunit assembly
0.44	GO:0006450	regulation of translational fidelity
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.58	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.70	GO:0015935	small ribosomal subunit
0.48	GO:0022626	cytosolic ribosome
0.41	GO:0000228	nuclear chromosome
0.41	GO:0005730	nucleolus
0.36	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.35	GO:0031012	extracellular matrix
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|Q24188|LBM_DROME
Protein late bloomer
Search

0.41	Tetraspanin

0.75	GO:0007416	synapse assembly
0.40	GO:0007166	cell surface receptor signaling pathway

0.60	GO:0005576	extracellular region
0.41	GO:0045202	synapse
0.41	GO:0030054	cell junction
0.39	GO:0005887	integral component of plasma membrane

sp|Q24192|RHOL_DROME
Ras-like GTP-binding protein RhoL
Search

0.91	Gtpase rho

0.76	GO:0007264	small GTPase mediated signal transduction
0.52	GO:0032949	regulation of alpha-glucan biosynthetic process
0.51	GO:0071963	establishment or maintenance of cell polarity regulating cell shape
0.50	GO:0030950	establishment or maintenance of actin cytoskeleton polarity
0.36	GO:0007516	hemocyte development
0.36	GO:0035099	hemocyte migration
0.36	GO:0035011	melanotic encapsulation of foreign target
0.35	GO:0007298	border follicle cell migration
0.35	GO:0007498	mesoderm development
0.34	GO:0022409	positive regulation of cell-cell adhesion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0047824	D-iditol 2-dehydrogenase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0004402	histone acetyltransferase activity
0.33	GO:0003855	3-dehydroquinate dehydratase activity

0.49	GO:0051286	cell tip
0.48	GO:0030427	site of polarized growth
0.46	GO:0032153	cell division site
0.45	GO:0005622	intracellular
0.33	GO:0005886	plasma membrane
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.35	EC:1.1.1.15	GO:0047824
0.34	KEGG:R02541	GO:0004767

sp|Q24206|BRC4_DROME
Broad-complex core protein isoform 6
Search

0.69	Broad-complex core protein isoform 6

0.60	GO:0007562	eclosion
0.59	GO:0007458	progression of morphogenetic furrow involved in compound eye morphogenesis
0.58	GO:0009608	response to symbiont
0.58	GO:0042332	gravitaxis
0.58	GO:0035070	salivary gland histolysis
0.58	GO:0048808	male genitalia morphogenesis
0.57	GO:0001752	compound eye photoreceptor fate commitment
0.57	GO:0071390	cellular response to ecdysone
0.56	GO:0040034	regulation of development, heterochronic
0.55	GO:0048747	muscle fiber development

0.52	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.38	GO:0003700	DNA binding transcription factor activity
0.36	GO:0046872	metal ion binding

0.44	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q24207|BOULE_DROME
Protein boule
Search

BOLL

0.78	Boule protein transcript variant 2

0.80	GO:0007281	germ cell development
0.52	GO:0008315	G2/MI transition of meiotic cell cycle
0.50	GO:0048137	spermatocyte division
0.50	GO:0045924	regulation of female receptivity
0.46	GO:0006417	regulation of translation
0.42	GO:0070935	3'-UTR-mediated mRNA stabilization
0.41	GO:0034250	positive regulation of cellular amide metabolic process
0.40	GO:0032270	positive regulation of cellular protein metabolic process
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process

0.76	GO:0003729	mRNA binding
0.44	GO:0008494	translation activator activity
0.37	GO:0046983	protein dimerization activity

0.49	GO:0043204	perikaryon
0.40	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0019013	viral nucleocapsid
0.35	GO:0030529	intracellular ribonucleoprotein complex

sp|Q24208|IF2G_DROME
Eukaryotic translation initiation factor 2 subunit 3
Search

0.41	Eukaryotic translation initiation factor

0.64	GO:0006413	translational initiation
0.45	GO:0045903	positive regulation of translational fidelity
0.43	GO:0002181	cytoplasmic translation
0.42	GO:0022618	ribonucleoprotein complex assembly
0.38	GO:0034968	histone lysine methylation
0.36	GO:0006414	translational elongation
0.32	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.65	GO:0003743	translation initiation factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0031369	translation initiation factor binding
0.40	GO:0000049	tRNA binding
0.38	GO:0018024	histone-lysine N-methyltransferase activity
0.36	GO:0045296	cadherin binding

0.47	GO:0005850	eukaryotic translation initiation factor 2 complex
0.45	GO:0043614	multi-eIF complex
0.43	GO:0016282	eukaryotic 43S preinitiation complex
0.43	GO:0033290	eukaryotic 48S preinitiation complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0005694	chromosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.38

GO:0018024

sp|Q24210|CSKP_DROME
Peripheral plasma membrane protein CASK
Search

0.54	Peripheral plasma membrane protein CASK

0.62	GO:0006468	protein phosphorylation
0.39	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.39	GO:0016080	synaptic vesicle targeting
0.38	GO:0007615	anesthesia-resistant memory
0.38	GO:0072375	medium-term memory
0.38	GO:1900073	regulation of neuromuscular synaptic transmission
0.38	GO:2000331	regulation of terminal button organization
0.38	GO:0016081	synaptic vesicle docking
0.38	GO:0008049	male courtship behavior
0.38	GO:0048149	behavioral response to ethanol

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0042043	neurexin family protein binding
0.37	GO:0005516	calmodulin binding
0.34	GO:0004385	guanylate kinase activity

0.38	GO:0061174	type I terminal bouton
0.37	GO:0031594	neuromuscular junction
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:2.7.4.8

GO:0004385

sp|Q24211|STNA_DROME
Protein stoned-A
Search

0.12

StnA

0.71	GO:0006897	endocytosis
0.70	GO:0036465	synaptic vesicle recycling
0.65	GO:0046907	intracellular transport
0.63	GO:0097480	establishment of synaptic vesicle localization
0.63	GO:0099003	vesicle-mediated transport in synapse
0.55	GO:0034613	cellular protein localization
0.53	GO:0015031	protein transport
0.36	GO:0051301	cell division

0.30

GO:0005515

protein binding

0.65	GO:0098793	presynapse
0.62	GO:0030131	clathrin adaptor complex
0.62	GO:0070382	exocytic vesicle
0.62	GO:0030139	endocytic vesicle
0.30	GO:0030054	cell junction

sp|Q24212|STNB_DROME
Protein stoned-B
Search

STNB

0.76	AP-1 complex subunit mu

0.75	GO:0030100	regulation of endocytosis
0.71	GO:0006897	endocytosis
0.63	GO:0036465	synaptic vesicle recycling
0.58	GO:0046907	intracellular transport
0.53	GO:1903421	regulation of synaptic vesicle recycling
0.53	GO:0034613	cellular protein localization
0.52	GO:0015031	protein transport
0.50	GO:0097480	establishment of synaptic vesicle localization
0.50	GO:0099003	vesicle-mediated transport in synapse
0.48	GO:0007268	chemical synaptic transmission

0.52	GO:0097110	scaffold protein binding
0.32	GO:0005044	scavenger receptor activity
0.31	GO:0004175	endopeptidase activity
0.31	GO:0008234	cysteine-type peptidase activity
0.31	GO:0017171	serine hydrolase activity

0.60	GO:0030131	clathrin adaptor complex
0.59	GO:0098793	presynapse
0.50	GO:0099738	cell cortex region
0.50	GO:0070382	exocytic vesicle
0.50	GO:0030139	endocytic vesicle
0.49	GO:0030863	cortical cytoskeleton
0.37	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.31

GO:0008234

sp|Q24214|CANB2_DROME
Calcineurin subunit B type 2
Search

0.71	Calcineurin subunit B type

0.50	GO:0030431	sleep
0.45	GO:0030241	skeletal muscle myosin thick filament assembly
0.44	GO:0045214	sarcomere organization
0.42	GO:0051321	meiotic cell cycle
0.37	GO:0006470	protein dephosphorylation
0.36	GO:0099643	signal release from synapse
0.36	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.35	GO:0043666	regulation of phosphoprotein phosphatase activity
0.35	GO:0016192	vesicle-mediated transport
0.35	GO:0006836	neurotransmitter transport

0.70	GO:0005509	calcium ion binding
0.37	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity
0.36	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0005516	calmodulin binding
0.34	GO:0043130	ubiquitin binding
0.34	GO:0003684	damaged DNA binding

0.37	GO:0005955	calcineurin complex
0.36	GO:0055120	striated muscle dense body
0.36	GO:0008021	synaptic vesicle
0.35	GO:0030017	sarcomere
0.34	GO:0000796	condensin complex
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus

0.36

GO:0004721

tr|Q24216|Q24216_DROME
Cyclin-dependent kinase 7
Search

CDK7

0.59	Cyclin-dependent kinase

0.63	GO:0006468	protein phosphorylation
0.52	GO:0006366	transcription by RNA polymerase II
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0050821	protein stabilization
0.49	GO:0001109	promoter clearance during DNA-templated transcription
0.48	GO:0051726	regulation of cell cycle
0.47	GO:0051301	cell division
0.45	GO:0071900	regulation of protein serine/threonine kinase activity
0.44	GO:0012501	programmed cell death
0.44	GO:0000278	mitotic cell cycle

0.84	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.51	GO:0008022	protein C-terminus binding
0.45	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.35	GO:0000988	transcription factor activity, protein binding

0.84	GO:0070985	TFIIK complex
0.53	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.38	GO:0005737	cytoplasm
0.37	GO:0031312	extrinsic component of organelle membrane
0.35	GO:0042585	germinal vesicle
0.34	GO:0019866	organelle inner membrane
0.33	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.84

EC:2.7.11.23

GO:0008353

sp|Q24238|APH4_DROME
Alkaline phosphatase 4
Search

0.46	Alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.54	GO:0042045	epithelial fluid transport
0.49	GO:0032504	multicellular organism reproduction
0.47	GO:0007399	nervous system development
0.36	GO:0033280	response to vitamin D
0.36	GO:0001958	endochondral ossification
0.35	GO:0071407	cellular response to organic cyclic compound
0.35	GO:0003006	developmental process involved in reproduction
0.34	GO:0046677	response to antibiotic
0.34	GO:0009612	response to mechanical stimulus

0.77	GO:0004035	alkaline phosphatase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0016462	pyrophosphatase activity

0.37	GO:0031225	anchored component of membrane
0.37	GO:0044421	extracellular region part
0.36	GO:0009986	cell surface
0.34	GO:0005886	plasma membrane
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.77

EC:3.1.3.1

GO:0004035

sp|Q24239|ANGEL_DROME
Protein angel
Search

0.69	Carbon catabolite repressor protein

0.42	GO:0007275	multicellular organism development
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:0016070	RNA metabolic process

0.83	GO:0008190	eukaryotic initiation factor 4E binding
0.72	GO:0019904	protein domain specific binding
0.39	GO:0004527	exonuclease activity
0.37	GO:0004519	endonuclease activity
0.36	GO:0004540	ribonuclease activity

0.77	GO:0005801	cis-Golgi network
0.75	GO:0048471	perinuclear region of cytoplasm
0.67	GO:0005783	endoplasmic reticulum
0.65	GO:0005829	cytosol
0.58	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q24246|DYIN_DROME
Cytoplasmic dynein 1 intermediate chain
Search

LOC108088619

0.77	Cytoplasmic dynein intermediate chain

0.73	GO:0007018	microtubule-based movement
0.40	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.40	GO:2000576	positive regulation of microtubule motor activity
0.39	GO:0030705	cytoskeleton-dependent intracellular transport
0.39	GO:0032781	positive regulation of ATPase activity
0.35	GO:0007291	sperm individualization
0.35	GO:0051642	centrosome localization
0.35	GO:0034501	protein localization to kinetochore
0.35	GO:0001754	eye photoreceptor cell differentiation
0.35	GO:0007051	spindle organization

0.40	GO:0045504	dynein heavy chain binding
0.40	GO:0045503	dynein light chain binding
0.40	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.36	GO:0034452	dynactin binding

0.82	GO:0005868	cytoplasmic dynein complex
0.38	GO:0036126	sperm flagellum
0.35	GO:0005765	lysosomal membrane
0.35	GO:0031965	nuclear membrane
0.34	GO:0043005	neuron projection
0.34	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:3.6.4.4

GO:0008574

sp|Q24247|ITA1_DROME
Integrin alpha-PS1
Search

0.93	Multiple edematous wings, isoform F

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.39	GO:0007432	salivary gland boundary specification
0.39	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.39	GO:0048567	ectodermal digestive tract morphogenesis
0.39	GO:0007414	axonal defasciculation
0.39	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.39	GO:0007426	tracheal outgrowth, open tracheal system
0.39	GO:0007427	epithelial cell migration, open tracheal system
0.39	GO:0007494	midgut development

0.38	GO:0050840	extracellular matrix binding
0.37	GO:0050839	cell adhesion molecule binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0004872	receptor activity
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004621	glycosylphosphatidylinositol phospholipase D activity

0.80	GO:0008305	integrin complex
0.38	GO:0009925	basal plasma membrane
0.38	GO:0016328	lateral plasma membrane
0.38	GO:0005925	focal adhesion
0.38	GO:0016324	apical plasma membrane

0.32

EC:3.1.4.50

GO:0004621

sp|Q24248|ARA_DROME
Homeobox protein araucan
Search

0.84	Homeobox protein caupolican

0.57	GO:0001745	compound eye morphogenesis
0.57	GO:0007476	imaginal disc-derived wing morphogenesis
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0042693	muscle cell fate commitment
0.56	GO:0010468	regulation of gene expression
0.55	GO:0045926	negative regulation of growth
0.54	GO:0035310	notum cell fate specification
0.51	GO:0048667	cell morphogenesis involved in neuron differentiation
0.51	GO:0048812	neuron projection morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.51	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.40	GO:0042803	protein homodimerization activity
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.61	GO:0005634	nucleus
0.33	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

sp|Q24251|ATP5H_DROME
ATP synthase subunit d, mitochondrial
Search

0.73	ATP synthase subunit d, mitochondrial

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.51	GO:0051881	regulation of mitochondrial membrane potential
0.51	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.51	GO:0008340	determination of adult lifespan
0.51	GO:0032007	negative regulation of TOR signaling
0.46	GO:0006979	response to oxidative stress
0.42	GO:0007287	Nebenkern assembly
0.36	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.33	GO:0007165	signal transduction

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.36	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0019829	cation-transporting ATPase activity
0.33	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.39	GO:0045265	proton-transporting ATP synthase, stator stalk

tr|Q24253|Q24253_DROME
AP complex subunit beta
Search

0.64	AP complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.45	GO:0048749	compound eye development
0.36	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0098657	import into cell
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0007368	determination of left/right symmetry
0.33	GO:0007507	heart development
0.33	GO:0035556	intracellular signal transduction

0.80	GO:0030276	clathrin binding
0.35	GO:0008565	protein transporter activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0019901	protein kinase binding
0.32	GO:0046872	metal ion binding

0.78	GO:0030131	clathrin adaptor complex
0.44	GO:0005905	clathrin-coated pit
0.44	GO:0005802	trans-Golgi network
0.44	GO:0030136	clathrin-coated vesicle
0.37	GO:0005886	plasma membrane
0.36	GO:0030666	endocytic vesicle membrane
0.36	GO:0030120	vesicle coat
0.32	GO:0005829	cytosol

0.34

GO:0004725

sp|Q24255|BARH1_DROME
Homeobox protein B-H1
Search

0.94	Homeobox protein B-H1

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0007479	leg disc proximal/distal pattern formation
0.53	GO:0008057	eye pigment granule organization
0.53	GO:0008052	sensory organ boundary specification
0.53	GO:0007455	eye-antennal disc morphogenesis
0.53	GO:0008407	chaeta morphogenesis
0.51	GO:0001751	compound eye photoreceptor cell differentiation
0.46	GO:1902679	negative regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.51	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.45	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.34	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0004000

sp|Q24256|BARH2_DROME
Homeobox protein B-H2
Search

0.83	Homeobox protein B-H2

0.57	GO:0007479	leg disc proximal/distal pattern formation
0.57	GO:0008057	eye pigment granule organization
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0008052	sensory organ boundary specification
0.56	GO:0007455	eye-antennal disc morphogenesis
0.56	GO:0008407	chaeta morphogenesis
0.56	GO:0010468	regulation of gene expression
0.55	GO:0001751	compound eye photoreceptor cell differentiation
0.48	GO:1902679	negative regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.36	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0004000

sp|Q24266|BTD_DROME
Transcription factor btd
Search

BTD

0.93	Transcription factor btd

0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.54	GO:0007376	cephalic furrow formation
0.51	GO:0042127	regulation of cell proliferation
0.51	GO:0007480	imaginal disc-derived leg morphogenesis
0.50	GO:2000026	regulation of multicellular organismal development
0.50	GO:0045893	positive regulation of transcription, DNA-templated
0.48	GO:0060284	regulation of cell development
0.48	GO:0030154	cell differentiation
0.46	GO:0007399	nervous system development
0.46	GO:1904828	positive regulation of hydrogen sulfide biosynthetic process

0.53	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003713	transcription coactivator activity
0.51	GO:0003676	nucleic acid binding
0.49	GO:0008134	transcription factor binding
0.45	GO:0071837	HMG box domain binding
0.44	GO:0042826	histone deacetylase binding
0.43	GO:0008022	protein C-terminus binding
0.41	GO:0042803	protein homodimerization activity
0.37	GO:0017151	DEAD/H-box RNA helicase binding
0.36	GO:0035035	histone acetyltransferase binding

0.50	GO:0005634	nucleus
0.43	GO:0017053	transcriptional repressor complex
0.42	GO:0070013	intracellular organelle lumen
0.40	GO:0000785	chromatin
0.38	GO:0005829	cytosol
0.34	GO:0032993	protein-DNA complex
0.32	GO:0031248	protein acetyltransferase complex
0.32	GO:1905368	peptidase complex
0.32	GO:1904949	ATPase complex
0.31	GO:0043234	protein complex

0.32

EC:1.2.1.27

GO:0004491

sp|Q24270|CAC1D_DROME
Voltage-dependent calcium channel type D subunit alpha-1
Search

0.55	Voltage-dependent L-type calcium channel subunit alpha

0.75	GO:0034765	regulation of ion transmembrane transport
0.75	GO:0070588	calcium ion transmembrane transport
0.36	GO:0086010	membrane depolarization during action potential
0.30	GO:0006936	muscle contraction
0.30	GO:0009987	cellular process
0.30	GO:0048731	system development
0.30	GO:0023052	signaling
0.30	GO:0050896	response to stimulus
0.30	GO:0070633	transepithelial transport
0.30	GO:0021700	developmental maturation

0.79	GO:0005245	voltage-gated calcium channel activity
0.33	GO:0005509	calcium ion binding

0.78	GO:0005891	voltage-gated calcium channel complex
0.30	GO:0098590	plasma membrane region
0.30	GO:0045177	apical part of cell
0.30	GO:0005622	intracellular

sp|Q24276|CDC37_DROME
Hsp90 co-chaperone Cdc37
Search

CDC37

0.73	Cell division cycle 37

0.44	GO:0051301	cell division
0.39	GO:0050821	protein stabilization
0.37	GO:0006457	protein folding
0.36	GO:0061098	positive regulation of protein tyrosine kinase activity
0.36	GO:0046579	positive regulation of Ras protein signal transduction
0.35	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.35	GO:0051321	meiotic cell cycle
0.35	GO:0032501	multicellular organismal process
0.34	GO:0007059	chromosome segregation
0.34	GO:0048856	anatomical structure development

0.78	GO:0019901	protein kinase binding
0.38	GO:0031072	heat shock protein binding
0.38	GO:0051087	chaperone binding
0.37	GO:0051082	unfolded protein binding
0.36	GO:0030296	protein tyrosine kinase activator activity

0.34	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q24278|CNGA_DROME
Cyclic nucleotide-gated cation channel subunit A
Search

0.76	Cyclic nucleotide-gated cation channel subunit A

0.60	GO:0034220	ion transmembrane transport
0.51	GO:0007601	visual perception
0.48	GO:0071804	cellular potassium ion transport
0.43	GO:0042391	regulation of membrane potential
0.37	GO:0070482	response to oxygen levels
0.36	GO:0019932	second-messenger-mediated signaling
0.35	GO:0009454	aerotaxis
0.35	GO:0003031	detection of carbon dioxide
0.35	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
0.35	GO:0010754	negative regulation of cGMP-mediated signaling

0.70	GO:0005216	ion channel activity
0.54	GO:0022836	gated channel activity
0.48	GO:0015079	potassium ion transmembrane transporter activity
0.38	GO:0030553	cGMP binding
0.34	GO:0004692	cGMP-dependent protein kinase activity
0.32	GO:0005515	protein binding

0.40	GO:0042622	photoreceptor outer segment membrane
0.40	GO:0005887	integral component of plasma membrane
0.36	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.35	GO:0097543	ciliary inversin compartment
0.34	GO:0030425	dendrite
0.32	GO:0005622	intracellular

0.34

EC:2.7.11.12

GO:0004692

sp|Q24292|DS_DROME
Protein dachsous
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.50	GO:0045317	equator specification
0.49	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.49	GO:0044331	cell-cell adhesion mediated by cadherin
0.49	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.48	GO:0035159	regulation of tube length, open tracheal system
0.48	GO:0045198	establishment of epithelial cell apical/basal polarity
0.48	GO:0035222	wing disc pattern formation
0.48	GO:0007480	imaginal disc-derived leg morphogenesis
0.48	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.46	GO:0045296	cadherin binding
0.35	GO:0004022	alcohol dehydrogenase (NAD) activity
0.31	GO:0004872	receptor activity
0.31	GO:0004871	signal transducer activity

0.55	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:1.1.1.1

GO:0004022

sp|Q24297|RUXF_DROME
Small nuclear ribonucleoprotein F
Search

SNRPF

0.81	Small nuclear ribonucleoprotein polypeptide F

0.81	GO:0000387	spliceosomal snRNP assembly
0.35	GO:0043606	formamide metabolic process
0.35	GO:0006548	histidine catabolic process
0.35	GO:0008334	histone mRNA metabolic process
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0006536	glutamate metabolic process
0.34	GO:0008217	regulation of blood pressure
0.34	GO:0097746	regulation of blood vessel diameter
0.34	GO:0051170	nuclear import
0.33	GO:0006836	neurotransmitter transport

0.56	GO:0003723	RNA binding
0.35	GO:0001604	urotensin II receptor activity
0.34	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.33	GO:0005515	protein binding

0.79	GO:0005732	small nucleolar ribonucleoprotein complex
0.76	GO:0005681	spliceosomal complex
0.57	GO:0019013	viral nucleocapsid
0.52	GO:0005683	U7 snRNP
0.52	GO:0005685	U1 snRNP
0.52	GO:0005687	U4 snRNP
0.51	GO:0034709	methylosome
0.51	GO:0034715	pICln-Sm protein complex
0.51	GO:0034719	SMN-Sm protein complex
0.44	GO:0005829	cytosol

0.34

EC:3.5.2

GO:0016812

sp|Q24298|CADE_DROME
DE-cadherin
Search

0.70	DE-cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0001748	optic lobe placode development
0.56	GO:0098729	germline stem cell symmetric division
0.56	GO:0045186	zonula adherens assembly
0.56	GO:0007506	gonadal mesoderm development
0.56	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.56	GO:0090254	cell elongation involved in imaginal disc-derived wing morphogenesis
0.56	GO:0044331	cell-cell adhesion mediated by cadherin
0.55	GO:0035099	hemocyte migration
0.55	GO:0007370	ventral furrow formation

0.70	GO:0005509	calcium ion binding
0.53	GO:0017022	myosin binding
0.52	GO:0008013	beta-catenin binding
0.49	GO:0042803	protein homodimerization activity
0.37	GO:0050839	cell adhesion molecule binding
0.35	GO:0004022	alcohol dehydrogenase (NAD) activity
0.35	GO:0004872	receptor activity
0.35	GO:0005179	hormone activity

0.56	GO:0005914	spot adherens junction
0.55	GO:0005886	plasma membrane
0.53	GO:0030175	filopodium
0.52	GO:0055037	recycling endosome
0.51	GO:0043296	apical junction complex
0.49	GO:0005938	cell cortex
0.49	GO:0019898	extrinsic component of membrane
0.43	GO:0098796	membrane protein complex
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.35

EC:1.1.1.1

GO:0004022

sp|Q24306|DIAP1_DROME
Death-associated inhibitor of apoptosis 1
Search

0.88	Death-associated inhibitor of apoptosis 1

0.85	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process
0.84	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.84	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.83	GO:0045035	sensory organ precursor cell division
0.83	GO:0048800	antennal morphogenesis
0.79	GO:0007289	spermatid nucleus differentiation
0.79	GO:0022416	chaeta development
0.79	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.78	GO:0070936	protein K48-linked ubiquitination
0.78	GO:0007298	border follicle cell migration

0.85	GO:0061663	NEDD8 ligase activity
0.84	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.82	GO:0089720	caspase binding
0.81	GO:1990381	ubiquitin-specific protease binding
0.78	GO:0031624	ubiquitin conjugating enzyme binding
0.72	GO:0031625	ubiquitin protein ligase binding
0.69	GO:0061630	ubiquitin protein ligase activity
0.41	GO:0008270	zinc ion binding
0.38	GO:0042802	identical protein binding
0.36	GO:0016874	ligase activity

0.58	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.36

GO:0016874

sp|Q24307|DIAP2_DROME
Death-associated inhibitor of apoptosis 2
Search

0.96	Death-associated inhibitor of apoptosis 2

0.86	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.86	GO:0061057	peptidoglycan recognition protein signaling pathway
0.85	GO:0033160	positive regulation of protein import into nucleus, translocation
0.85	GO:0022416	chaeta development
0.84	GO:0070534	protein K63-linked ubiquitination
0.84	GO:0070936	protein K48-linked ubiquitination
0.83	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.81	GO:0050829	defense response to Gram-negative bacterium
0.80	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.76	GO:0006915	apoptotic process

0.86	GO:0089720	caspase binding
0.85	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.77	GO:0031625	ubiquitin protein ligase binding
0.74	GO:0061630	ubiquitin protein ligase activity
0.41	GO:0016874	ligase activity
0.40	GO:0008270	zinc ion binding

0.77	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.41

GO:0016874

sp|Q24311|CUL1_DROME
Cullin homolog 1
Search

CUL1

0.70	Putative e3 ubiquitin ligase cullin 1 component

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.48	GO:0048731	system development
0.48	GO:0046627	negative regulation of insulin receptor signaling pathway
0.47	GO:0006513	protein monoubiquitination
0.47	GO:0032007	negative regulation of TOR signaling
0.47	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.47	GO:0071695	anatomical structure maturation
0.47	GO:0048469	cell maturation
0.46	GO:0008283	cell proliferation
0.45	GO:0006915	apoptotic process

0.79	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0016874	ligase activity
0.33	GO:0005484	SNAP receptor activity

0.76	GO:0031461	cullin-RING ubiquitin ligase complex
0.50	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex
0.41	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.36

GO:0016874

sp|Q24312|EWG_DROME
DNA-binding protein Ewg
Search

EWG

0.66	DNA-binding protein Ewg

0.57	GO:0007527	adult somatic muscle development
0.56	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.54	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.53	GO:0007560	imaginal disc morphogenesis
0.52	GO:0007517	muscle organ development
0.51	GO:0007417	central nervous system development
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0006351	transcription, DNA-templated

0.54	GO:0003677	DNA binding
0.30	GO:0003824	catalytic activity

0.44

GO:0005634

nucleus

sp|Q24314|VPS18_DROME
Vacuolar protein sorting-associated protein 18 homolog
Search

0.68	Vacuolar protein sorting-associated protein 18

0.68	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.61	GO:0007032	endosome organization
0.60	GO:0007041	lysosomal transport
0.60	GO:0006728	pteridine biosynthetic process
0.58	GO:0048072	compound eye pigmentation
0.58	GO:2000366	positive regulation of STAT protein import into nucleus
0.58	GO:0008057	eye pigment granule organization
0.58	GO:0061357	positive regulation of Wnt protein secretion
0.57	GO:0046158	ocellus pigment metabolic process

0.59	GO:0019905	syntaxin binding
0.44	GO:0003779	actin binding
0.42	GO:0030674	protein binding, bridging
0.35	GO:0008270	zinc ion binding
0.34	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0008408	3'-5' exonuclease activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding

0.62	GO:0030897	HOPS complex
0.57	GO:0005764	lysosome
0.55	GO:0005768	endosome
0.51	GO:0045202	synapse
0.47	GO:0005829	cytosol
0.47	GO:0005884	actin filament
0.47	GO:0030123	AP-3 adaptor complex
0.46	GO:0044433	cytoplasmic vesicle part
0.39	GO:0098852	lytic vacuole membrane
0.36	GO:0005776	autophagosome

sp|Q24317|PRI1_DROME
DNA primase small subunit
Search

0.45	DNA primase small subunit

0.75	GO:0006269	DNA replication, synthesis of RNA primer
0.34	GO:0071897	DNA biosynthetic process
0.32	GO:0006508	proteolysis

0.78	GO:0003896	DNA primase activity
0.41	GO:0003697	single-stranded DNA binding
0.35	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0046872	metal ion binding

0.55	GO:0044454	nuclear chromosome part
0.49	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.49	GO:0030894	replisome
0.47	GO:0000785	chromatin
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.7.7

GO:0003896

sp|Q24318|TFDP_DROME
Transcription factor Dp
Search

0.74	Transcription factor Dp

0.67	GO:0007049	cell cycle
0.60	GO:0045850	positive regulation of nurse cell apoptotic process
0.59	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.50	GO:0051726	regulation of cell cycle
0.49	GO:0010604	positive regulation of macromolecule metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.54	GO:0008134	transcription factor binding
0.45	GO:0003712	transcription cofactor activity
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0015299	solute:proton antiporter activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.58	GO:0031523	Myb complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0016705

sp|Q24319|OST48_DROME
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Search

0.78	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

0.85	GO:0018279	protein N-linked glycosylation via asparagine
0.48	GO:0034389	lipid particle organization
0.46	GO:0007030	Golgi organization
0.35	GO:0006814	sodium ion transport
0.33	GO:0055085	transmembrane transport

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0005215	transporter activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.33	GO:1990234	transferase complex
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

sp|Q24320|RPAB2_DROME
DNA-directed RNA polymerases I, II, and III subunit RPABC2
Search

0.66	DNA-directed RNA polymerase I

0.58	GO:0006351	transcription, DNA-templated
0.34	GO:0035019	somatic stem cell population maintenance
0.34	GO:0032481	positive regulation of type I interferon production
0.34	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0045815	positive regulation of gene expression, epigenetic
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.33	GO:0000398	mRNA splicing, via spliceosome

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0005665	DNA-directed RNA polymerase II, core complex
0.44	GO:0005736	DNA-directed RNA polymerase I complex
0.44	GO:0005666	DNA-directed RNA polymerase III complex
0.35	GO:0001650	fibrillar center
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.70

GO:0003899

sp|Q24322|SEM1A_DROME
Semaphorin-1A
Search

0.82	Semaphorin

0.38	GO:2000305	semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance
0.37	GO:0016199	axon midline choice point recognition
0.37	GO:0008039	synaptic target recognition
0.37	GO:0045792	negative regulation of cell size
0.37	GO:0008045	motor neuron axon guidance
0.36	GO:0048813	dendrite morphogenesis
0.36	GO:0007416	synapse assembly

0.37	GO:0030215	semaphorin receptor binding
0.36	GO:0008201	heparin binding

0.37

GO:0005887

integral component of plasma membrane

sp|Q24323|SEM2A_DROME
Semaphorin-2A
Search

0.83	Semaphorin

0.79	GO:0071678	olfactory bulb axon guidance
0.77	GO:0070983	dendrite guidance
0.75	GO:0008039	synaptic target recognition
0.65	GO:0042756	drinking behavior
0.65	GO:0097374	sensory neuron axon guidance
0.64	GO:0007629	flight behavior
0.62	GO:0050919	negative chemotaxis
0.62	GO:0070593	dendrite self-avoidance
0.62	GO:0007632	visual behavior
0.60	GO:0050918	positive chemotaxis

0.36

GO:0005515

protein binding

0.43	GO:0005887	integral component of plasma membrane
0.38	GO:0005576	extracellular region
0.37	GO:0005829	cytosol
0.37	GO:0012505	endomembrane system

sp|Q24324|DSOR1_DROME
Dual specificity mitogen-activated protein kinase kinase dSOR1
Search

0.72	Dual specificity mitogen-activated protein kinase kinase

0.63	GO:0006468	protein phosphorylation
0.48	GO:0071481	cellular response to X-ray
0.48	GO:0042386	hemocyte differentiation
0.48	GO:0007362	terminal region determination
0.47	GO:0070372	regulation of ERK1 and ERK2 cascade
0.47	GO:0007095	mitotic G2 DNA damage checkpoint
0.47	GO:0007298	border follicle cell migration
0.47	GO:0033314	mitotic DNA replication checkpoint
0.46	GO:0042461	photoreceptor cell development
0.42	GO:0032147	activation of protein kinase activity

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004708	MAP kinase kinase activity
0.38	GO:0004728	signal transducer, downstream of receptor, with protein tyrosine phosphatase activity
0.38	GO:0097110	scaffold protein binding
0.38	GO:0047485	protein N-terminus binding
0.38	GO:0043539	protein serine/threonine kinase activator activity

0.44	GO:0000793	condensed chromosome
0.44	GO:0005635	nuclear envelope
0.37	GO:0005829	cytosol
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|Q24325|TAF2_DROME
Transcription initiation factor TFIID subunit 2
Search

TAF2

0.32	Transcription initiation factor TFIID subunit

0.57	GO:0006508	proteolysis
0.52	GO:0006413	translational initiation
0.52	GO:0007221	positive regulation of transcription of Notch receptor target
0.52	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly
0.50	GO:0046427	positive regulation of JAK-STAT cascade
0.50	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter
0.36	GO:0000086	G2/M transition of mitotic cell cycle
0.35	GO:0014070	response to organic cyclic compound
0.34	GO:1901796	regulation of signal transduction by p53 class mediator
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter

0.63	GO:0008237	metallopeptidase activity
0.59	GO:0008270	zinc ion binding
0.53	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.53	GO:0003743	translation initiation factor activity
0.53	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.48	GO:0044212	transcription regulatory region DNA binding
0.46	GO:0008134	transcription factor binding
0.44	GO:0043565	sequence-specific DNA binding
0.39	GO:0003682	chromatin binding
0.34	GO:0004177	aminopeptidase activity

0.80	GO:0005669	transcription factor TFIID complex
0.36	GO:0033276	transcription factor TFTC complex
0.34	GO:0005730	nucleolus

0.34

EC:3.4.11

GO:0004177

sp|Q24337|ER_DROME
Protein enhancer of rudimentary
Search

0.85	Enhancer of rudimentary homolog

0.85	GO:0045747	positive regulation of Notch signaling pathway
0.70	GO:0006221	pyrimidine nucleotide biosynthetic process
0.67	GO:0007049	cell cycle
0.34	GO:0001649	osteoblast differentiation
0.34	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.33	GO:0006213	pyrimidine nucleoside metabolic process

0.48	GO:0008327	methyl-CpG binding
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.47	GO:0034709	methylosome
0.46	GO:0030496	midbody
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q24338|ESC_DROME
Polycomb protein esc
Search

0.90	Embryonic ectoderm development

0.78	GO:0016571	histone methylation
0.56	GO:0031062	positive regulation of histone methylation
0.56	GO:0018022	peptidyl-lysine methylation
0.53	GO:0040029	regulation of gene expression, epigenetic
0.49	GO:0045892	negative regulation of transcription, DNA-templated
0.49	GO:2000011	regulation of adaxial/abaxial pattern formation
0.48	GO:0061085	regulation of histone H3-K27 methylation
0.48	GO:0071514	genetic imprinting
0.47	GO:0016458	gene silencing
0.47	GO:1990823	response to leukemia inhibitory factor

0.59	GO:0046976	histone methyltransferase activity (H3-K27 specific)
0.52	GO:0003682	chromatin binding
0.51	GO:0042802	identical protein binding
0.46	GO:0008047	enzyme activator activity
0.45	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0044877	macromolecular complex binding
0.37	GO:0046974	histone methyltransferase activity (H3-K9 specific)
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0046872	metal ion binding

0.84	GO:0035098	ESC/E(Z) complex
0.50	GO:0005700	polytene chromosome
0.49	GO:0001739	sex chromatin
0.48	GO:0045120	pronucleus
0.42	GO:0005829	cytosol

0.35

EC:3.1.4.17

GO:0004114

sp|Q24342|FNG_DROME
Fringe glycosyltransferase
Search

0.75	Fringe glycosyltransferase

0.54	GO:0007389	pattern specification process
0.52	GO:0036099	female germ-line stem cell population maintenance
0.51	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.51	GO:0007480	imaginal disc-derived leg morphogenesis
0.51	GO:0007293	germarium-derived egg chamber formation
0.50	GO:0042335	cuticle development
0.50	GO:0001745	compound eye morphogenesis
0.50	GO:0008593	regulation of Notch signaling pathway
0.49	GO:0007219	Notch signaling pathway
0.48	GO:0006493	protein O-linked glycosylation

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.39	GO:0046872	metal ion binding
0.33	GO:0051015	actin filament binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0005524	ATP binding

0.55	GO:0030173	integral component of Golgi membrane
0.51	GO:0005797	Golgi medial cisterna
0.45	GO:0005783	endoplasmic reticulum
0.33	GO:0016459	myosin complex
0.33	GO:0005634	nucleus

0.65

GO:0016757

sp|Q24352|GBRAL_DROME
Gamma-aminobutyric acid receptor alpha-like
Search

0.85	Glycine receptor

0.68	GO:1904456	negative regulation of neuronal action potential
0.65	GO:0060012	synaptic transmission, glycinergic
0.61	GO:0007165	signal transduction
0.61	GO:0042752	regulation of circadian rhythm
0.60	GO:0034220	ion transmembrane transport
0.57	GO:0006821	chloride transport
0.47	GO:0006812	cation transport
0.40	GO:0060078	regulation of postsynaptic membrane potential

0.72	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.63	GO:0099095	ligand-gated anion channel activity
0.57	GO:0022835	transmitter-gated channel activity
0.57	GO:0005254	chloride channel activity
0.55	GO:0005261	cation channel activity

0.51	GO:0005886	plasma membrane
0.40	GO:0034707	chloride channel complex
0.39	GO:0098794	postsynapse
0.39	GO:0030054	cell junction

sp|Q24368|ISWI_DROME
Chromatin-remodeling complex ATPase chain Iswi
Search

ISWI

0.39	Chromatin-remodeling complex ATPase chain Iswi

0.81	GO:0043044	ATP-dependent chromatin remodeling
0.74	GO:0016569	covalent chromatin modification
0.46	GO:0035063	nuclear speck organization
0.46	GO:0016584	nucleosome positioning
0.45	GO:0035041	sperm chromatin decondensation
0.44	GO:0035092	sperm chromatin condensation
0.44	GO:0035076	ecdysone receptor-mediated signaling pathway
0.44	GO:0042766	nucleosome mobilization
0.43	GO:0006334	nucleosome assembly
0.43	GO:0042752	regulation of circadian rhythm

0.83	GO:0031491	nucleosome binding
0.67	GO:0004386	helicase activity
0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008134	transcription factor binding
0.37	GO:0042393	histone binding

0.84	GO:0016589	NURF complex
0.46	GO:0031213	RSF complex
0.46	GO:0016590	ACF complex
0.45	GO:0008623	CHRAC
0.43	GO:0005700	polytene chromosome
0.41	GO:0005667	transcription factor complex
0.38	GO:0005677	chromatin silencing complex
0.37	GO:0001650	fibrillar center
0.37	GO:0043596	nuclear replication fork
0.36	GO:0000793	condensed chromosome

0.61	EC:3.6.1.3	GO:0016887
0.33	KEGG:R03648	GO:0004816

sp|Q24371|L2DTL_DROME
Protein lethal(2)denticleless
Search

0.14	Lethal(2)denticleless

0.50	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.48	GO:0016567	protein ubiquitination
0.48	GO:0019985	translesion synthesis
0.48	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.47	GO:0009411	response to UV
0.47	GO:0006508	proteolysis
0.47	GO:0045732	positive regulation of protein catabolic process
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.44	GO:0044257	cellular protein catabolic process
0.44	GO:0015031	protein transport

0.47	GO:0004252	serine-type endopeptidase activity
0.45	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0046872	metal ion binding
0.39	GO:0005164	tumor necrosis factor receptor binding
0.36	GO:0016758	transferase activity, transferring hexosyl groups
0.36	GO:0031490	chromatin DNA binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0042393	histone binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0043531	ADP binding

0.58	GO:0005634	nucleus
0.50	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex
0.49	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.46	GO:0005813	centrosome
0.42	GO:0005829	cytosol
0.42	GO:0043233	organelle lumen
0.42	GO:0005739	mitochondrion
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.47	EC:3.4.21	GO:0004252
0.45	KEGG:R03876	GO:0004842

sp|Q24372|LACH_DROME
Lachesin
Search

0.63	Fibroblast growth factor receptor

0.59	GO:0019991	septate junction assembly
0.58	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.57	GO:0061343	cell adhesion involved in heart morphogenesis
0.56	GO:0035151	regulation of tube size, open tracheal system
0.54	GO:0016331	morphogenesis of embryonic epithelium
0.52	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation

0.50	GO:0042803	protein homodimerization activity
0.35	GO:0004725	protein tyrosine phosphatase activity

0.58	GO:0005918	septate junction
0.39	GO:0031225	anchored component of membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0004725

sp|Q24388|LSP2_DROME
Larval serum protein 2
Search

LSP2

0.87	Arylphorin subunit alpha

0.86	GO:0016201	synaptic target inhibition
0.84	GO:0008045	motor neuron axon guidance
0.34	GO:0055114	oxidation-reduction process

0.46	GO:0045735	nutrient reservoir activity
0.36	GO:0004503	monophenol monooxygenase activity
0.34	GO:0046872	metal ion binding

0.87

GO:0005616

larval serum protein complex

0.36

EC:1.14.18.1

GO:0004503

sp|Q24395|MTK_DROME
Metchnikowin
Search

0.96	Metchnikowin

0.86	GO:0019732	antifungal humoral response
0.85	GO:0019731	antibacterial humoral response
0.85	GO:0050830	defense response to Gram-positive bacterium
0.84	GO:0050829	defense response to Gram-negative bacterium
0.50	GO:0031640	killing of cells of other organism
0.50	GO:0045087	innate immune response

0.66

GO:0005576

extracellular region

sp|Q24400|MLP2_DROME
Muscle LIM protein Mlp84B
Search

0.66	Muscle LIM protein isoform 1

0.30	GO:0048869	cellular developmental process
0.30	GO:0050793	regulation of developmental process
0.30	GO:0007517	muscle organ development
0.30	GO:0070925	organelle assembly
0.30	GO:0007010	cytoskeleton organization
0.30	GO:0097435	supramolecular fiber organization
0.30	GO:0009888	tissue development
0.30	GO:0051239	regulation of multicellular organismal process
0.30	GO:0009653	anatomical structure morphogenesis
0.30	GO:0030029	actin filament-based process

0.54	GO:0046872	metal ion binding
0.30	GO:0008307	structural constituent of muscle

0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0043292	contractile fiber
0.30	GO:0005856	cytoskeleton
0.30	GO:0044422	organelle part

tr|Q24404|Q24404_DROME
LP10995p
Search

0.90	DBF4-type zinc finger-containing protein 2 homolog

0.76	GO:0007286	spermatid development
0.42	GO:0001558	regulation of cell growth
0.39	GO:0030317	flagellated sperm motility
0.39	GO:0035082	axoneme assembly
0.38	GO:0006457	protein folding
0.35	GO:0007275	multicellular organism development
0.35	GO:0060070	canonical Wnt signaling pathway
0.35	GO:0007018	microtubule-based movement
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.43	GO:0005520	insulin-like growth factor binding
0.39	GO:0051082	unfolded protein binding
0.35	GO:0008013	beta-catenin binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0003713	transcription coactivator activity
0.34	GO:0005201	extracellular matrix structural constituent

0.78	GO:0036126	sperm flagellum
0.41	GO:0016272	prefoldin complex
0.40	GO:0044441	ciliary part
0.40	GO:0099513	polymeric cytoskeletal fiber
0.39	GO:0005576	extracellular region
0.39	GO:0005581	collagen trimer
0.34	GO:0045111	intermediate filament cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q24407|ATP5J_DROME
ATP synthase-coupling factor 6, mitochondrial
Search

0.92	Mitochondrial ATP synthase coupling factor

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.37	GO:1904263	positive regulation of TORC1 signaling
0.37	GO:0090114	COPII-coated vesicle budding
0.35	GO:0015031	protein transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0005198	structural molecule activity
0.34	GO:0016887	ATPase activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.37	GO:0005756	mitochondrial proton-transporting ATP synthase, central stalk
0.37	GO:0030127	COPII vesicle coat
0.36	GO:0000139	Golgi membrane

0.34

GO:0016887

sp|Q24418|NMDA1_DROME
Glutamate [NMDA] receptor subunit 1
Search

NMDAR1

0.79	Ionotropic glutamate receptor

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.53	GO:0072375	medium-term memory
0.52	GO:0042331	phototaxis
0.52	GO:0050975	sensory perception of touch
0.52	GO:0008355	olfactory learning
0.51	GO:0048149	behavioral response to ethanol
0.51	GO:0007616	long-term memory
0.48	GO:0055074	calcium ion homeostasis

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.49	GO:0099094	ligand-gated cation channel activity
0.47	GO:0022843	voltage-gated cation channel activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004383	guanylate cyclase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.52	GO:0017146	NMDA selective glutamate receptor complex
0.48	GO:0014069	postsynaptic density

0.33

EC:4.6.1.2

GO:0004383

sp|Q24423|NOC_DROME
Zinc finger protein Noc
Search

NOC

0.53	Zinc finger protein Noc

0.62	GO:0008056	ocellus development
0.60	GO:0007430	terminal branching, open tracheal system
0.60	GO:0001752	compound eye photoreceptor fate commitment
0.58	GO:0035218	leg disc development
0.56	GO:0035220	wing disc development
0.55	GO:0007420	brain development
0.54	GO:0008283	cell proliferation
0.51	GO:0010629	negative regulation of gene expression
0.44	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.44	GO:0060644	mammary gland epithelial cell differentiation

0.51	GO:0003676	nucleic acid binding
0.42	GO:0070491	repressing transcription factor binding
0.35	GO:0046872	metal ion binding

0.43	GO:0016363	nuclear matrix
0.37	GO:0043234	protein complex
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q24432|OMB_DROME
Optomotor-blind protein
Search

0.90	optomotor-blind protein isoform X2

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0048100	wing disc anterior/posterior pattern formation
0.39	GO:0035265	organ growth
0.39	GO:0048066	developmental pigmentation
0.39	GO:0001745	compound eye morphogenesis
0.39	GO:0007476	imaginal disc-derived wing morphogenesis
0.37	GO:0051253	negative regulation of RNA metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0005515	protein binding
0.35	GO:0031419	cobalamin binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q24434|ORD_DROME
Protein ORD
Search

0.88	GO:0007065	male meiosis sister chromatid cohesion
0.88	GO:0007066	female meiosis sister chromatid cohesion
0.87	GO:0007060	male meiosis chromosome segregation
0.86	GO:0051457	maintenance of protein location in nucleus
0.75	GO:0000278	mitotic cell cycle

0.43

GO:0005515

protein binding

0.86	GO:0001674	female germ cell nucleus
0.86	GO:0001673	male germ cell nucleus
0.80	GO:0000779	condensed chromosome, centromeric region
0.76	GO:0005635	nuclear envelope
0.75	GO:0000790	nuclear chromatin
0.30	GO:0031224	intrinsic component of membrane

sp|Q24437|MST40_DROME
Protein male-specific 40
Search

0.56	Protein male-specific 40

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

sp|Q24439|ATPO_DROME
ATP synthase subunit O, mitochondrial
Search

0.79	F-type H+-transporting ATPase subunit O

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.36	GO:0006839	mitochondrial transport
0.35	GO:0046907	intracellular transport
0.34	GO:0006334	nucleosome assembly
0.33	GO:0006418	tRNA aminoacylation for protein translation

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.35	GO:0005496	steroid binding
0.34	GO:0032403	protein complex binding
0.34	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism
0.33	GO:0003677	DNA binding
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0008144	drug binding
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.38	GO:0043209	myelin sheath
0.36	GO:0045269	proton-transporting ATP synthase, central stalk
0.34	GO:0031012	extracellular matrix
0.34	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:3.6.3.6

GO:0008553

sp|Q24451|MAN2_DROME
Alpha-mannosidase 2
Search

0.47	Alpha-mannosidase

0.81	GO:0006013	mannose metabolic process
0.43	GO:0006517	protein deglycosylation
0.43	GO:0006491	N-glycan processing
0.37	GO:0016063	rhodopsin biosynthetic process
0.37	GO:0035010	encapsulation of foreign target
0.37	GO:0006486	protein glycosylation
0.37	GO:0007585	respiratory gaseous exchange
0.37	GO:0048286	lung alveolus development
0.36	GO:0060042	retina morphogenesis in camera-type eye
0.36	GO:0042538	hyperosmotic salinity response

0.79	GO:0004559	alpha-mannosidase activity
0.70	GO:0030246	carbohydrate binding
0.53	GO:0046872	metal ion binding
0.36	GO:0004970	ionotropic glutamate receptor activity
0.36	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds
0.34	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0051287	NAD binding
0.32	GO:0005515	protein binding

0.41	GO:0098791	Golgi subcompartment
0.40	GO:0098588	bounding membrane of organelle
0.36	GO:0005801	cis-Golgi network
0.35	GO:0005615	extracellular space
0.35	GO:0005768	endosome
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.79	EC:3.2.1.24	GO:0004559
0.34	KEGG:R00214	GO:0004471

tr|Q24454|Q24454_DROME
LD16810p
Search

0.85	GO:0007502	digestive tract mesoderm development
0.83	GO:0051306	mitotic sister chromatid separation
0.81	GO:0007443	Malpighian tubule morphogenesis
0.77	GO:0051298	centrosome duplication
0.76	GO:0008406	gonad development
0.74	GO:0002064	epithelial cell development
0.74	GO:0000281	mitotic cytokinesis
0.68	GO:0007399	nervous system development

0.42

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

sp|Q24459|PCL_DROME
Polycomb protein Pcl
Search

0.94	Polycomb protein Pcl

0.65	GO:0050832	defense response to fungus
0.59	GO:0045892	negative regulation of transcription, DNA-templated
0.58	GO:0006325	chromatin organization
0.44	GO:0007419	ventral cord development
0.40	GO:0061086	negative regulation of histone H3-K27 methylation
0.40	GO:0061087	positive regulation of histone H3-K27 methylation
0.40	GO:0007379	segment specification
0.39	GO:1990823	response to leukemia inhibitory factor
0.39	GO:0019827	stem cell population maintenance
0.39	GO:0048863	stem cell differentiation

0.62	GO:0003682	chromatin binding
0.54	GO:0046872	metal ion binding
0.51	GO:0003700	DNA binding transcription factor activity
0.47	GO:0003677	DNA binding
0.46	GO:0140034	methylation-dependent protein binding
0.45	GO:0042393	histone binding
0.38	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0003723	RNA binding
0.33	GO:0005199	structural constituent of cell wall
0.32	GO:0140096	catalytic activity, acting on a protein

0.68	GO:0035098	ESC/E(Z) complex
0.39	GO:0005694	chromosome
0.39	GO:0005925	focal adhesion
0.33	GO:0005737	cytoplasm
0.32	GO:0005813	centrosome
0.30	GO:0016020	membrane

0.32

EC:2.6.1

GO:0008483

sp|Q24472|RBF_DROME
Retinoblastoma family protein
Search

RBF

0.90	Retinoblastoma family protein

0.73	GO:0051726	regulation of cell cycle
0.71	GO:0034088	maintenance of mitotic sister chromatid cohesion
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.70	GO:1905634	regulation of protein localization to chromatin
0.70	GO:0042023	DNA endoreduplication
0.69	GO:1900117	regulation of execution phase of apoptosis
0.69	GO:1904262	negative regulation of TORC1 signaling
0.67	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.66	GO:0051101	regulation of DNA binding
0.65	GO:0008361	regulation of cell size

0.62	GO:0001012	RNA polymerase II regulatory region DNA binding
0.60	GO:0008134	transcription factor binding
0.34	GO:0061676	importin-alpha family protein binding
0.34	GO:1990841	promoter-specific chromatin binding
0.34	GO:0019899	enzyme binding
0.33	GO:0097718	disordered domain specific binding
0.33	GO:0051219	phosphoprotein binding
0.33	GO:0001047	core promoter binding
0.33	GO:0042802	identical protein binding

0.72	GO:0035189	Rb-E2F complex
0.71	GO:0031523	Myb complex
0.58	GO:0000785	chromatin
0.40	GO:0005654	nucleoplasm
0.34	GO:0005819	spindle
0.33	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex
0.33	GO:0032806	carboxy-terminal domain protein kinase complex

sp|Q24475|RPR_DROME
Cell death protein rpr
Search

0.87	GO:2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.87	GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death
0.87	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.86	GO:0035096	larval midgut cell programmed cell death
0.86	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.86	GO:0071480	cellular response to gamma radiation
0.85	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.84	GO:0043524	negative regulation of neuron apoptotic process
0.52	GO:0035193	larval central nervous system remodeling
0.51	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress

0.85	GO:0031624	ubiquitin conjugating enzyme binding
0.79	GO:0031625	ubiquitin protein ligase binding
0.75	GO:0005543	phospholipid binding
0.75	GO:0042803	protein homodimerization activity

0.78

GO:0005741

mitochondrial outer membrane

sp|Q24478|CP190_DROME
Centrosome-associated zinc finger protein CP190
Search

0.71	Centrosome-associated zinc finger protein CP190

0.75	GO:0035191	nuclear axial expansion
0.73	GO:0090202	gene looping
0.71	GO:0031937	positive regulation of chromatin silencing
0.62	GO:0051493	regulation of cytoskeleton organization
0.41	GO:0016569	covalent chromatin modification
0.41	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0007017	microtubule-based process
0.37	GO:0006351	transcription, DNA-templated
0.32	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.32	GO:0055085	transmembrane transport

0.73	GO:0031208	POZ domain binding
0.72	GO:0043035	chromatin insulator sequence binding
0.61	GO:0042803	protein homodimerization activity
0.61	GO:0008017	microtubule binding
0.36	GO:0046872	metal ion binding
0.32	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0022857	transmembrane transporter activity

0.72	GO:0005704	polytene chromosome band
0.70	GO:0000242	pericentriolar material
0.66	GO:0005876	spindle microtubule
0.62	GO:0000793	condensed chromosome
0.52	GO:0005634	nucleus
0.42	GO:0005875	microtubule associated complex
0.32	GO:0031463	Cul3-RING ubiquitin ligase complex
0.30	GO:0016020	membrane

0.32

GO:0004842

sp|Q24488|ROR1_DROME
Tyrosine-protein kinase transmembrane receptor Ror
Search

0.53	Tyrosine-protein kinase transmembrane receptor Ror

0.76	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.73	GO:0018108	peptidyl-tyrosine phosphorylation
0.49	GO:0048731	system development
0.45	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.45	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.45	GO:0007605	sensory perception of sound
0.43	GO:0016055	Wnt signaling pathway
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0006950	response to stress

0.74	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0017147	Wnt-protein binding
0.46	GO:0042813	Wnt-activated receptor activity
0.35	GO:0004930	G-protein coupled receptor activity
0.32	GO:0016787	hydrolase activity

0.46	GO:0043679	axon terminus
0.44	GO:0043235	receptor complex
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74

EC:2.7.10.1

GO:0004714

sp|Q24491|RX21_DROME
RNA-binding protein Rsf1
Search

0.38	Repressor splicing factor 1

0.39	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.39	GO:0031440	regulation of mRNA 3'-end processing
0.39	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.38	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.34	GO:0008380	RNA splicing
0.33	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.41	GO:0008270	zinc ion binding

0.35	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q24492|RFA1_DROME
Replication protein A 70 kDa DNA-binding subunit
Search

0.68	Replication protein A subunit

0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.64	GO:0006281	DNA repair
0.39	GO:0034502	protein localization to chromosome
0.38	GO:0000723	telomere maintenance
0.38	GO:0007507	heart development
0.34	GO:0030491	heteroduplex formation
0.33	GO:0007127	meiosis I
0.33	GO:0043934	sporulation
0.33	GO:0016567	protein ubiquitination

0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.31	GO:0016491	oxidoreductase activity

0.61	GO:0005634	nucleus
0.47	GO:0030894	replisome
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043234	protein complex
0.33	GO:0000781	chromosome, telomeric region
0.33	GO:0000793	condensed chromosome
0.33	GO:0005829	cytosol

0.31

GO:0016491

sp|Q24498|RYR_DROME
Ryanodine receptor
Search

LOC108090257

0.88	Ryanodine receptor

0.84	GO:0051209	release of sequestered calcium ion into cytosol
0.35	GO:0035206	regulation of hemocyte proliferation
0.35	GO:0072347	response to anesthetic
0.35	GO:0060047	heart contraction
0.34	GO:0006936	muscle contraction
0.33	GO:0007275	multicellular organism development

0.85	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.35	GO:0005509	calcium ion binding

0.35	GO:0033017	sarcoplasmic reticulum membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q24509|STX5_DROME
Syntaxin-5
Search

0.68

Syntaxin

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.52	GO:0060305	regulation of cell diameter
0.52	GO:0007030	Golgi organization
0.51	GO:0035167	larval lymph gland hemopoiesis
0.51	GO:0007112	male meiosis cytokinesis
0.48	GO:0000281	mitotic cytokinesis
0.48	GO:0006878	cellular copper ion homeostasis
0.47	GO:0007283	spermatogenesis

0.80	GO:0005484	SNAP receptor activity
0.46	GO:0042803	protein homodimerization activity
0.43	GO:0047485	protein N-terminus binding
0.42	GO:0045296	cadherin binding
0.42	GO:0000149	SNARE binding
0.34	GO:0031625	ubiquitin protein ligase binding

0.48	GO:0005794	Golgi apparatus
0.48	GO:0005801	cis-Golgi network
0.42	GO:0031201	SNARE complex
0.40	GO:0031982	vesicle
0.39	GO:0005829	cytosol
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0031984	organelle subcompartment
0.36	GO:0098793	presynapse
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment

sp|Q24523|BUN2_DROME
Protein bunched, class 2/F/G isoform
Search

LOC108094493

0.94	protein bunched, class 2/F/G isoform isoform X1

0.59	GO:0008101	decapentaplegic signaling pathway
0.58	GO:0036335	intestinal stem cell homeostasis
0.58	GO:0009996	negative regulation of cell fate specification
0.58	GO:0046843	dorsal appendage formation
0.58	GO:0002052	positive regulation of neuroblast proliferation
0.57	GO:0016319	mushroom body development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0001751	compound eye photoreceptor cell differentiation
0.57	GO:0045746	negative regulation of Notch signaling pathway

0.61	GO:0003700	DNA binding transcription factor activity
0.41	GO:0042803	protein homodimerization activity
0.34	GO:0008061	chitin binding

0.40	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q24524|SING_DROME
Protein singed
Search

0.82	Fascinlike [Tribolium castaneum]

0.75	GO:0007015	actin filament organization
0.50	GO:0048800	antennal morphogenesis
0.50	GO:0035099	hemocyte migration
0.49	GO:0030033	microvillus assembly
0.49	GO:0035017	cuticle pattern formation
0.49	GO:0008407	chaeta morphogenesis
0.49	GO:0046847	filopodium assembly
0.49	GO:0035317	imaginal disc-derived wing hair organization
0.48	GO:0007163	establishment or maintenance of cell polarity
0.47	GO:0016358	dendrite development

0.80	GO:0030674	protein binding, bridging
0.78	GO:0051015	actin filament binding
0.34	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity

0.58	GO:0005856	cytoskeleton
0.46	GO:0034399	nuclear periphery
0.46	GO:0043025	neuronal cell body
0.46	GO:0043005	neuron projection
0.45	GO:0099512	supramolecular fiber
0.44	GO:0005737	cytoplasm
0.41	GO:0043234	protein complex
0.35	GO:0032421	stereocilium bundle
0.34	GO:0098858	actin-based cell projection
0.30	GO:0016020	membrane

0.34

EC:1.1.1.35

GO:0003857

sp|Q24533|DICH_DROME
SOX domain-containing protein dichaete
Search

0.96	SOX domain-containing protein dichaete

0.52	GO:0014019	neuroblast development
0.52	GO:0070983	dendrite guidance
0.51	GO:0002168	instar larval development
0.51	GO:0060810	intracellular mRNA localization involved in pattern specification process
0.51	GO:0007442	hindgut morphogenesis
0.51	GO:0009950	dorsal/ventral axis specification
0.50	GO:0007350	blastoderm segmentation
0.50	GO:0035120	post-embryonic appendage morphogenesis
0.49	GO:0007411	axon guidance
0.48	GO:0007420	brain development

0.55	GO:0003677	DNA binding
0.50	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.50	GO:0003730	mRNA 3'-UTR binding
0.46	GO:0008134	transcription factor binding
0.36	GO:0003682	chromatin binding
0.36	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.36	GO:0005667	transcription factor complex
0.34	GO:0044446	intracellular organelle part

sp|Q24535|SRF_DROME
Serum response factor homolog
Search

0.61	SRF-type transcription factor (DNA-binding and dimerization domain)

0.73	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.54	GO:0035209	pupal development
0.54	GO:0007430	terminal branching, open tracheal system
0.54	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.53	GO:0007614	short-term memory
0.53	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.53	GO:0002168	instar larval development
0.53	GO:0030431	sleep
0.46	GO:0030154	cell differentiation

0.78	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.77	GO:0000987	proximal promoter sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.52	GO:0033613	activating transcription factor binding
0.50	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0016301	kinase activity
0.32	GO:0032555	purine ribonucleotide binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q24536|SSL_DROME
Suppressor-of-stellate-like protein
Search

0.51	Casein kinase II subunit beta'

0.76	GO:0045859	regulation of protein kinase activity
0.47	GO:0016310	phosphorylation
0.42	GO:0080163	regulation of protein serine/threonine phosphatase activity
0.41	GO:0018210	peptidyl-threonine modification
0.40	GO:0006356	regulation of transcription by RNA polymerase I
0.39	GO:0006359	regulation of transcription by RNA polymerase III
0.39	GO:0018209	peptidyl-serine modification
0.39	GO:0033673	negative regulation of kinase activity
0.39	GO:0051172	negative regulation of nitrogen compound metabolic process
0.38	GO:0010605	negative regulation of macromolecule metabolic process

0.79	GO:0019887	protein kinase regulator activity
0.48	GO:0016301	kinase activity
0.39	GO:0019210	kinase inhibitor activity
0.37	GO:0019209	kinase activator activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0003682	chromatin binding
0.35	GO:0019904	protein domain specific binding
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0042802	identical protein binding
0.34	GO:0008134	transcription factor binding

0.83	GO:0005956	protein kinase CK2 complex
0.40	GO:0034456	UTP-C complex
0.35	GO:0031519	PcG protein complex
0.35	GO:0032545	CURI complex
0.35	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.35

GO:0016773

sp|Q24537|HMG2_DROME
High mobility group protein DSP1
Search

0.67	High mobility group protein DSP1

0.41	GO:0002437	inflammatory response to antigenic stimulus
0.40	GO:0050830	defense response to Gram-positive bacterium
0.40	GO:0050829	defense response to Gram-negative bacterium
0.40	GO:0032392	DNA geometric change
0.40	GO:0032496	response to lipopolysaccharide
0.38	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.38	GO:0008348	negative regulation of antimicrobial humoral response
0.38	GO:0043388	positive regulation of DNA binding
0.37	GO:0042493	response to drug
0.37	GO:0048856	anatomical structure development

0.54	GO:0003677	DNA binding
0.37	GO:0008134	transcription factor binding
0.36	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0008144	drug binding
0.34	GO:0010181	FMN binding
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0050786	RAGE receptor binding
0.34	GO:0042056	chemoattractant activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.38	GO:0005615	extracellular space
0.37	GO:0005694	chromosome
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

sp|Q24546|SYN_DROME
Synapsin
Search

SYN

0.64

Synapsin

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.41	GO:0071632	optomotor response
0.40	GO:0072553	terminal button organization
0.40	GO:0008355	olfactory learning
0.40	GO:0051124	synaptic growth at neuromuscular junction
0.40	GO:0008049	male courtship behavior

0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0046872	metal ion binding

0.82	GO:0008021	synaptic vesicle
0.39	GO:0043195	terminal bouton
0.38	GO:0030054	cell junction
0.34	GO:0099501	exocytic vesicle membrane
0.34	GO:0014069	postsynaptic density
0.30	GO:0031224	intrinsic component of membrane

sp|Q24547|STX1A_DROME
Syntaxin-1A
Search

SYX1A

0.73	Snare protein syntaxin 1

0.82	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.66	GO:0006886	intracellular protein transport
0.66	GO:0061025	membrane fusion
0.38	GO:0097480	establishment of synaptic vesicle localization
0.38	GO:0099504	synaptic vesicle cycle
0.38	GO:0099643	signal release from synapse
0.38	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.37	GO:0048284	organelle fusion
0.37	GO:0006413	translational initiation

0.82	GO:0000149	SNARE binding
0.77	GO:0005484	SNAP receptor activity
0.37	GO:0003743	translation initiation factor activity
0.33	GO:0003746	translation elongation factor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005622	intracellular
0.37	GO:0098793	presynapse
0.36	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.35	GO:0044306	neuron projection terminus
0.35	GO:0033267	axon part
0.35	GO:0098796	membrane protein complex
0.34	GO:0030054	cell junction
0.34	GO:0098805	whole membrane
0.34	GO:0005886	plasma membrane

sp|Q24558|EXO1_DROME
Exonuclease 1
Search

0.37	Exonuclease

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0016446	somatic hypermutation of immunoglobulin genes
0.48	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.48	GO:0002312	B cell activation involved in immune response
0.47	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.35	GO:0051321	meiotic cell cycle
0.35	GO:0000732	strand displacement
0.34	GO:0001325	formation of extrachromosomal circular DNA
0.34	GO:0090737	telomere maintenance via telomere trimming

0.84	GO:0035312	5'-3' exodeoxyribonuclease activity
0.55	GO:0003677	DNA binding
0.50	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.49	GO:0008297	single-stranded DNA exodeoxyribonuclease activity
0.48	GO:0048256	flap endonuclease activity
0.44	GO:0003682	chromatin binding
0.35	GO:0046872	metal ion binding
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding

0.60	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0004523

sp|Q24560|TBB1_DROME
Tubulin beta-1 chain
Search

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.35	GO:0016203	muscle attachment

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm

sp|Q24562|U2AF2_DROME
Splicing factor U2AF 50 kDa subunit
Search

0.71	U2 snRNP auxiliary factor large subunit

0.71	GO:0008380	RNA splicing
0.68	GO:0006397	mRNA processing
0.36	GO:0046833	positive regulation of RNA export from nucleus
0.35	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0032958	inositol phosphate biosynthetic process
0.34	GO:0051168	nuclear export
0.33	GO:0016192	vesicle-mediated transport
0.33	GO:0006508	proteolysis
0.33	GO:0016310	phosphorylation

0.59	GO:0003723	RNA binding
0.34	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.60	GO:0005634	nucleus
0.37	GO:0019013	viral nucleocapsid
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043234	protein complex
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

GO:0008234

sp|Q24563|DOPR2_DROME
Dopamine receptor 2
Search

0.85	Octopamine receptor oamb

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0019933	cAMP-mediated signaling
0.40	GO:0007267	cell-cell signaling
0.40	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration
0.39	GO:0060359	response to ammonium ion
0.39	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep
0.39	GO:1990834	response to odorant
0.39	GO:0071870	cellular response to catecholamine stimulus
0.39	GO:1903223	positive regulation of oxidative stress-induced neuron death
0.39	GO:0035690	cellular response to drug

0.72	GO:0004930	G-protein coupled receptor activity
0.41	GO:0030594	neurotransmitter receptor activity
0.35	GO:0070405	ammonium ion binding
0.35	GO:0005272	sodium channel activity
0.35	GO:0099589	serotonin receptor activity
0.35	GO:0043176	amine binding
0.34	GO:0042165	neurotransmitter binding
0.34	GO:0001653	peptide receptor activity
0.33	GO:1901338	catecholamine binding
0.32	GO:0008144	drug binding

0.44	GO:0005886	plasma membrane
0.39	GO:0030285	integral component of synaptic vesicle membrane
0.33	GO:0005903	brush border
0.33	GO:0097730	non-motile cilium
0.33	GO:0044441	ciliary part
0.32	GO:0030286	dynein complex

sp|Q24564|MERH_DROME
Moesin/ezrin/radixin homolog 2
Search

0.79	Neurofibromin 2 (Bilateral acoustic neuroma)

0.77	GO:0008285	negative regulation of cell proliferation
0.57	GO:0046669	regulation of compound eye retinal cell programmed cell death
0.57	GO:0008101	decapentaplegic signaling pathway
0.57	GO:0019094	pole plasm mRNA localization
0.56	GO:0007112	male meiosis cytokinesis
0.56	GO:0060251	regulation of glial cell proliferation
0.56	GO:0007291	sperm individualization
0.56	GO:0035330	regulation of hippo signaling
0.56	GO:0014014	negative regulation of gliogenesis
0.56	GO:0046621	negative regulation of organ growth

0.72	GO:0003779	actin binding
0.49	GO:0042802	identical protein binding
0.36	GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity
0.34	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.69	GO:0005856	cytoskeleton
0.59	GO:0036375	Kibra-Ex-Mer complex
0.58	GO:0016006	Nebenkern
0.53	GO:0016324	apical plasma membrane
0.52	GO:0005912	adherens junction
0.50	GO:0005938	cell cortex
0.38	GO:0045169	fusome
0.30	GO:0016021	integral component of membrane

0.36

EC:3.6.1

GO:0008796

sp|Q24567|NETA_DROME
Netrin-A
Search

0.84	Putative netrin axonal chemotropic factor

0.65	GO:2000289	regulation of photoreceptor cell axon guidance
0.63	GO:0070983	dendrite guidance
0.61	GO:0008347	glial cell migration
0.61	GO:0008045	motor neuron axon guidance
0.59	GO:0048749	compound eye development
0.36	GO:0007432	salivary gland boundary specification
0.36	GO:0008039	synaptic target recognition
0.33	GO:0009190	cyclic nucleotide biosynthetic process
0.33	GO:0050918	positive chemotaxis
0.33	GO:0035556	intracellular signal transduction

0.34	GO:0005102	receptor binding
0.33	GO:0016849	phosphorus-oxygen lyase activity

0.66	GO:0005576	extracellular region
0.62	GO:0044295	axonal growth cone
0.38	GO:0005829	cytosol
0.34	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.33

EC:4.6

GO:0016849

sp|Q24568|NETB_DROME
Netrin-B
Search

NETB

0.97

Netrin-B

0.70	GO:2000289	regulation of photoreceptor cell axon guidance
0.68	GO:0070983	dendrite guidance
0.67	GO:0007432	salivary gland boundary specification
0.65	GO:0008347	glial cell migration
0.65	GO:0008045	motor neuron axon guidance
0.64	GO:0008039	synaptic target recognition
0.63	GO:0048749	compound eye development
0.43	GO:0050918	positive chemotaxis
0.34	GO:0055085	transmembrane transport

0.38

GO:0005515

protein binding

0.66	GO:0044295	axonal growth cone
0.66	GO:0005576	extracellular region
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q24570|GRIM_DROME
Cell death protein Grim
Search

0.86	GO:2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.85	GO:0035006	melanization defense response
0.84	GO:0010623	programmed cell death involved in cell development
0.84	GO:1901216	positive regulation of neuron death
0.82	GO:0008340	determination of adult lifespan
0.82	GO:0043524	negative regulation of neuron apoptotic process
0.79	GO:0097190	apoptotic signaling pathway
0.51	GO:0035193	larval central nervous system remodeling
0.49	GO:1902742	apoptotic process involved in development
0.47	GO:0048477	oogenesis

0.73	GO:0042803	protein homodimerization activity
0.38	GO:1902557	5'-adenylyl sulfate transmembrane transporter activity
0.38	GO:0050825	ice binding
0.38	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0016887	ATPase activity

0.59	GO:0005739	mitochondrion
0.37	GO:0005858	axonemal dynein complex
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

sp|Q24572|CAF1_DROME
Probable histone-binding protein Caf1
Search

0.72	Chromatin assembly factor 1 subunit

0.44	GO:0031497	chromatin assembly
0.43	GO:0006338	chromatin remodeling
0.43	GO:0034728	nucleosome organization
0.42	GO:0065004	protein-DNA complex assembly
0.42	GO:0016569	covalent chromatin modification
0.40	GO:0045814	negative regulation of gene expression, epigenetic
0.40	GO:0007379	segment specification
0.40	GO:0018393	internal peptidyl-lysine acetylation
0.39	GO:0016458	gene silencing
0.39	GO:0000281	mitotic cytokinesis

0.44	GO:0042826	histone deacetylase binding
0.40	GO:0031491	nucleosome binding
0.39	GO:0042393	histone binding
0.39	GO:0042054	histone methyltransferase activity
0.39	GO:0008094	DNA-dependent ATPase activity
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0016279	protein-lysine N-methyltransferase activity
0.35	GO:0004402	histone acetyltransferase activity
0.35	GO:0070615	nucleosome-dependent ATPase activity
0.35	GO:0035035	histone acetyltransferase binding

0.61	GO:0005634	nucleus
0.47	GO:0033186	CAF-1 complex
0.44	GO:0034708	methyltransferase complex
0.43	GO:0017053	transcriptional repressor complex
0.41	GO:0000785	chromatin
0.41	GO:0070013	intracellular organelle lumen
0.40	GO:0031523	Myb complex
0.40	GO:1904949	ATPase complex
0.39	GO:0005700	polytene chromosome
0.38	GO:0005829	cytosol

0.35

GO:0016279

sp|Q24573|DRI_DROME
Protein dead ringer
Search

RETN

0.87	Retained, isoform C

0.59	GO:0045924	regulation of female receptivity
0.58	GO:0008049	male courtship behavior
0.57	GO:0048813	dendrite morphogenesis
0.56	GO:0009880	embryonic pattern specification
0.55	GO:0042063	gliogenesis
0.55	GO:0009952	anterior/posterior pattern specification
0.55	GO:0007517	muscle organ development
0.55	GO:0007411	axon guidance
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0045893	positive regulation of transcription, DNA-templated

0.57	GO:0070491	repressing transcription factor binding
0.55	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.44	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003682	chromatin binding
0.40	GO:0042803	protein homodimerization activity
0.33	GO:0004930	G-protein coupled receptor activity

0.61	GO:0005634	nucleus
0.41	GO:0045121	membrane raft
0.38	GO:0005829	cytosol
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|Q24574|UBPE_DROME
Ubiquitin carboxyl-terminal hydrolase 64E
Search

0.39	Ubiquitin carboxyl-terminal hydrolase

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.59	GO:0042675	compound eye cone cell differentiation
0.56	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.56	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.55	GO:0031935	regulation of chromatin silencing
0.53	GO:0050821	protein stabilization
0.40	GO:0006284	base-excision repair
0.40	GO:0042981	regulation of apoptotic process
0.37	GO:2000117	negative regulation of cysteine-type endopeptidase activity

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.38	GO:0071987	WD40-repeat domain binding

0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.37	GO:0019005	SCF ubiquitin ligase complex
0.30	GO:0016021	integral component of membrane

0.77

GO:0036459

sp|Q24583|VATF1_DROME
V-type proton ATPase subunit F 1
Search

0.73	V-type proton ATPase subunit F

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.39	GO:1901207	regulation of heart looping
0.39	GO:0060036	notochord cell vacuolation
0.38	GO:0070121	Kupffer's vesicle development
0.38	GO:1902017	regulation of cilium assembly
0.37	GO:0060041	retina development in camera-type eye
0.36	GO:0042127	regulation of cell proliferation
0.35	GO:0090383	phagosome acidification
0.34	GO:0033572	transferrin transport
0.34	GO:0008286	insulin receptor signaling pathway

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.34	GO:0042624	ATPase activity, uncoupled
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.81	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.46	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.40	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.34	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q24592|JAK_DROME
Tyrosine-protein kinase hopscotch
Search

0.59	Tyrosine-protein kinase hopscotch

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0045317	equator specification
0.64	GO:0060031	mediolateral intercalation
0.63	GO:0030713	ovarian follicle cell stalk formation
0.63	GO:0007538	primary sex determination
0.63	GO:0042386	hemocyte differentiation
0.63	GO:0045610	regulation of hemocyte differentiation
0.63	GO:0016318	ommatidial rotation
0.63	GO:0031453	positive regulation of heterochromatin assembly
0.62	GO:0003383	apical constriction

0.76	GO:0004713	protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0019199	transmembrane receptor protein kinase activity
0.41	GO:0005102	receptor binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0019903	protein phosphatase binding
0.33	GO:0004190	aspartic-type endopeptidase activity

0.61	GO:0005856	cytoskeleton
0.55	GO:0009898	cytoplasmic side of plasma membrane
0.51	GO:0005829	cytosol
0.42	GO:0019897	extrinsic component of plasma membrane
0.40	GO:0005887	integral component of plasma membrane
0.39	GO:0012505	endomembrane system
0.34	GO:0043005	neuron projection
0.33	GO:0044433	cytoplasmic vesicle part
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

0.76

GO:0004713

sp|Q24595|XPC_DROME
DNA repair protein complementing XP-C cells homolog
Search

0.10	DNA repair protein complementing XP-C cells homolog

0.73	GO:0006289	nucleotide-excision repair
0.47	GO:0010224	response to UV-B
0.47	GO:0031573	intra-S DNA damage checkpoint
0.47	GO:0070914	UV-damage excision repair
0.45	GO:1901990	regulation of mitotic cell cycle phase transition
0.41	GO:0051276	chromosome organization
0.41	GO:0006298	mismatch repair
0.39	GO:0010996	response to auditory stimulus
0.36	GO:0042493	response to drug
0.34	GO:0065004	protein-DNA complex assembly

0.73	GO:0003684	damaged DNA binding
0.45	GO:0003697	single-stranded DNA binding
0.35	GO:0000405	bubble DNA binding
0.35	GO:0000404	heteroduplex DNA loop binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:1990391	DNA repair complex
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.40	GO:0044446	intracellular organelle part
0.40	GO:0005739	mitochondrion
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q26263|DPN_DROME
Protein deadpan
Search

0.61	GO:0007540	sex determination, establishment of X:A ratio
0.60	GO:0048864	stem cell development
0.58	GO:0007219	Notch signaling pathway
0.58	GO:0045931	positive regulation of mitotic cell cycle
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0050767	regulation of neurogenesis
0.57	GO:0010720	positive regulation of cell development
0.57	GO:0051962	positive regulation of nervous system development
0.57	GO:0008345	larval locomotory behavior
0.57	GO:0014016	neuroblast differentiation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0035326	enhancer binding
0.54	GO:1990837	sequence-specific double-stranded DNA binding
0.46	GO:0042826	histone deacetylase binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0051087	chaperone binding
0.43	GO:0042802	identical protein binding
0.35	GO:0008134	transcription factor binding
0.34	GO:0008432	JUN kinase binding

0.61	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|Q26307|ANA_DROME
Protein anachronism
Search

ANA

0.95	Anachronism, isoform B

0.72	GO:0007399	nervous system development
0.69	GO:0030154	cell differentiation
0.42	GO:0007026	negative regulation of microtubule depolymerization
0.42	GO:1900006	positive regulation of dendrite development
0.41	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.41	GO:0030307	positive regulation of cell growth
0.41	GO:0048639	positive regulation of developmental growth
0.41	GO:0031346	positive regulation of cell projection organization
0.41	GO:0051962	positive regulation of nervous system development
0.40	GO:0120035	regulation of plasma membrane bounded cell projection organization

0.40	GO:0043565	sequence-specific DNA binding
0.37	GO:0008168	methyltransferase activity
0.37	GO:0008270	zinc ion binding

0.64	GO:0005576	extracellular region
0.39	GO:0005634	nucleus

0.37

GO:0008168

sp|Q26365|ADT_DROME
ADP,ATP carrier protein
Search

0.51	Adenine nucleotide translocase

0.55	GO:0055085	transmembrane transport
0.48	GO:0015866	ADP transport
0.48	GO:2001171	positive regulation of ATP biosynthetic process
0.47	GO:0015867	ATP transport
0.47	GO:0051900	regulation of mitochondrial depolarization
0.47	GO:0051124	synaptic growth at neuromuscular junction
0.47	GO:0070050	neuron cellular homeostasis
0.46	GO:0051560	mitochondrial calcium ion homeostasis
0.46	GO:0046716	muscle cell cellular homeostasis
0.46	GO:0006839	mitochondrial transport

0.57	GO:0022857	transmembrane transporter activity
0.40	GO:0003779	actin binding
0.34	GO:0031625	ubiquitin protein ligase binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.43	GO:0045202	synapse
0.34	GO:0071817	MMXD complex
0.34	GO:0042645	mitochondrial nucleoid
0.34	GO:0043209	myelin sheath
0.30	GO:0031224	intrinsic component of membrane

sp|Q26366|VG_DROME
Protein vestigial
Search

0.70	GO:0007451	dorsal/ventral lineage restriction, imaginal disc
0.70	GO:0007473	wing disc proximal/distal pattern formation
0.68	GO:0016204	determination of muscle attachment site
0.67	GO:0090254	cell elongation involved in imaginal disc-derived wing morphogenesis
0.67	GO:0007482	haltere development
0.66	GO:0044719	regulation of imaginal disc-derived wing size
0.65	GO:0048190	wing disc dorsal/ventral pattern formation
0.65	GO:0007480	imaginal disc-derived leg morphogenesis
0.64	GO:0007525	somatic muscle development
0.63	GO:0001745	compound eye morphogenesis

0.63	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.62	GO:0008022	protein C-terminus binding
0.35	GO:0003677	DNA binding
0.35	GO:0008312	7S RNA binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.35	GO:0048500	signal recognition particle
0.32	GO:0043590	bacterial nucleoid

sp|Q26377|CORZ_DROME
Pro-corazonin
Search

CRZ

0.82	Preprocorazonin

0.85	GO:0045823	positive regulation of heart contraction
0.73	GO:0006117	acetaldehyde metabolic process
0.69	GO:0071361	cellular response to ethanol
0.68	GO:0048149	behavioral response to ethanol
0.64	GO:0007218	neuropeptide signaling pathway
0.51	GO:0010469	regulation of receptor activity

0.87	GO:0071858	corazonin receptor binding
0.56	GO:0005184	neuropeptide hormone activity

0.58	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|Q26416|CUA1_DROME
Adult cuticle protein 1
Search

0.97	Adult cuticle protein 1

0.55	GO:0006836	neurotransmitter transport
0.44	GO:0035521	monoubiquitinated histone deubiquitination
0.44	GO:0055085	transmembrane transport

0.63	GO:0042302	structural constituent of cuticle
0.56	GO:0005328	neurotransmitter:sodium symporter activity
0.42	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.36	GO:0003677	DNA binding

0.30

GO:0044425

membrane part

sp|Q26454|MCM4_DROME
DNA replication licensing factor MCM4
Search

0.44	DNA replication licensing factor mcm4-A

0.75	GO:0006270	DNA replication initiation
0.70	GO:0032392	DNA geometric change
0.46	GO:0007052	mitotic spindle organization
0.36	GO:0030174	regulation of DNA-dependent DNA replication initiation
0.35	GO:0001878	response to yeast

0.71	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0070035	purine NTP-dependent helicase activity
0.38	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.80	GO:0042555	MCM complex
0.61	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.34	GO:0005694	chromosome

sp|Q27237|TID_DROME
Protein tumorous imaginal discs, mitochondrial
Search

0.37	Chaperone protein dnaj

0.75	GO:0009408	response to heat
0.69	GO:0006457	protein folding
0.42	GO:0007224	smoothened signaling pathway
0.36	GO:0007005	mitochondrion organization
0.35	GO:0007275	multicellular organism development
0.32	GO:0008285	negative regulation of cell proliferation
0.32	GO:0000122	negative regulation of transcription by RNA polymerase II

0.78	GO:0031072	heat shock protein binding
0.71	GO:0051082	unfolded protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0046872	metal ion binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0005113	patched binding

0.39	GO:0005829	cytosol
0.38	GO:0005739	mitochondrion
0.36	GO:0031968	organelle outer membrane
0.32	GO:0005884	actin filament
0.32	GO:0009295	nucleoid
0.32	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q27241|Q27241_DROME
Ecdysone-induced gene 71Ed
Search

0.92	Ecdysone-induced gene 71Ed

0.77	GO:0007552	metamorphosis
0.64	GO:0042742	defense response to bacterium

0.56

GO:0005576

extracellular region

sp|Q27268|DX39B_DROME
ATP-dependent RNA helicase WM6
Search

0.39	ATP-dependent RNA helicase

0.50	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.48	GO:0051028	mRNA transport
0.48	GO:0006405	RNA export from nucleus
0.45	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.43	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0006338	chromatin remodeling
0.42	GO:0010501	RNA secondary structure unwinding
0.38	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0046784	viral mRNA export from host cell nucleus
0.35	GO:2000002	negative regulation of DNA damage checkpoint

0.57	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0008186	RNA-dependent ATPase activity
0.40	GO:0042802	identical protein binding
0.37	GO:0140098	catalytic activity, acting on RNA
0.35	GO:0043008	ATP-dependent protein binding
0.33	GO:0008134	transcription factor binding

0.45	GO:0005700	polytene chromosome
0.43	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0005737	cytoplasm
0.34	GO:0043234	protein complex
0.34	GO:0120114	Sm-like protein family complex
0.30	GO:0016020	membrane

sp|Q27272|TAF9_DROME
Transcription initiation factor TFIID subunit 9
Search

0.62	Transcription initiation factor TFIID subunit

0.69	GO:0006352	DNA-templated transcription, initiation
0.55	GO:0006413	translational initiation
0.51	GO:0043966	histone H3 acetylation
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0065004	protein-DNA complex assembly
0.47	GO:0006366	transcription by RNA polymerase II
0.45	GO:0030707	ovarian follicle cell development
0.44	GO:0030307	positive regulation of cell growth
0.44	GO:0007219	Notch signaling pathway
0.43	GO:0050821	protein stabilization

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003743	translation initiation factor activity
0.52	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.49	GO:0004402	histone acetyltransferase activity
0.46	GO:0008134	transcription factor binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0070742	C2H2 zinc finger domain binding
0.39	GO:0051117	ATPase binding
0.39	GO:0002039	p53 binding
0.38	GO:0003713	transcription coactivator activity

0.51	GO:0005669	transcription factor TFIID complex
0.51	GO:0070461	SAGA-type complex
0.46	GO:1905368	peptidase complex
0.40	GO:0070761	pre-snoRNP complex
0.38	GO:0071339	MLL1 complex

0.49

GO:0004402

sp|Q27294|CAZ_DROME
RNA-binding protein cabeza
Search

0.37	RNA-binding protein cabeza

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.50	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.50	GO:0008345	larval locomotory behavior
0.50	GO:0051124	synaptic growth at neuromuscular junction
0.48	GO:0008344	adult locomotory behavior
0.48	GO:0048749	compound eye development
0.37	GO:0006367	transcription initiation from RNA polymerase II promoter
0.37	GO:0000398	mRNA splicing, via spliceosome

0.58	GO:0003723	RNA binding
0.51	GO:0046872	metal ion binding
0.35	GO:0016874	ligase activity
0.34	GO:0003712	transcription cofactor activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.33	GO:0031072	heat shock protein binding
0.33	GO:0003677	DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.48	GO:0035327	transcriptionally active chromatin
0.44	GO:0005654	nucleoplasm
0.37	GO:0071013	catalytic step 2 spliceosome
0.37	GO:0090575	RNA polymerase II transcription factor complex
0.36	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.33	GO:0009507	chloroplast
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016021	integral component of membrane

0.35

GO:0016874

sp|Q27297|RAD51_DROME
DNA repair protein Rad51 homolog
Search

0.74	DNA repair protein RAD51 homolog B

0.85	GO:1990426	mitotic recombination-dependent replication fork processing
0.76	GO:0000724	double-strand break repair via homologous recombination
0.51	GO:0010569	regulation of double-strand break repair via homologous recombination
0.50	GO:0043279	response to alkaloid
0.49	GO:1903046	meiotic cell cycle process
0.48	GO:0009951	polarity specification of dorsal/ventral axis
0.48	GO:0009949	polarity specification of anterior/posterior axis
0.48	GO:0000280	nuclear division
0.48	GO:0007294	germarium-derived oocyte fate determination
0.47	GO:0030717	karyosome formation

0.73	GO:0000150	recombinase activity
0.72	GO:0003697	single-stranded DNA binding
0.71	GO:0003690	double-stranded DNA binding
0.69	GO:0008094	DNA-dependent ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0070182	DNA polymerase binding
0.43	GO:0000400	four-way junction DNA binding

0.60	GO:0005634	nucleus
0.43	GO:0000793	condensed chromosome
0.43	GO:0035861	site of double-strand break
0.41	GO:0000781	chromosome, telomeric region
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0043233	organelle lumen
0.40	GO:0000785	chromatin
0.39	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion
0.37	GO:0043234	protein complex

sp|Q27324|RYK1_DROME
Tyrosine-protein kinase Drl
Search

0.52	Tyrosine-protein kinase Drl

0.63	GO:0006468	protein phosphorylation
0.61	GO:0016204	determination of muscle attachment site
0.58	GO:0061643	chemorepulsion of axon
0.58	GO:0007435	salivary gland morphogenesis
0.56	GO:0007482	haltere development
0.55	GO:0070983	dendrite guidance
0.55	GO:0016199	axon midline choice point recognition
0.55	GO:0008355	olfactory learning
0.53	GO:0007613	memory
0.48	GO:0007165	signal transduction

0.64	GO:0004672	protein kinase activity
0.55	GO:0017147	Wnt-protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046982	protein heterodimerization activity
0.50	GO:0019901	protein kinase binding
0.49	GO:0042803	protein homodimerization activity
0.43	GO:0004888	transmembrane signaling receptor activity

0.54	GO:0043235	receptor complex
0.51	GO:0030425	dendrite
0.51	GO:0030424	axon
0.45	GO:0005887	integral component of plasma membrane
0.36	GO:0001725	stress fiber
0.35	GO:0005634	nucleus
0.35	GO:0005773	vacuole
0.32	GO:0005576	extracellular region

sp|Q27331|VATA2_DROME
V-type proton ATPase catalytic subunit A isoform 2
Search

0.51	Vacuolar ATP synthase catalytic subunit A

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.62	GO:0046034	ATP metabolic process
0.45	GO:0048388	endosomal lumen acidification
0.44	GO:0007446	imaginal disc growth
0.44	GO:0071456	cellular response to hypoxia
0.44	GO:0035149	lumen formation, open tracheal system
0.44	GO:0008593	regulation of Notch signaling pathway
0.41	GO:0016197	endosomal transport
0.34	GO:0007035	vacuolar acidification
0.34	GO:0043547	positive regulation of GTPase activity

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0005096	GTPase activator activity
0.32	GO:0046872	metal ion binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.44	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.42	GO:0016324	apical plasma membrane
0.39	GO:0005765	lysosomal membrane
0.36	GO:0016471	vacuolar proton-transporting V-type ATPase complex

sp|Q27333|NT56_DROME
Lethal(2)neighbour of tid protein
Search

0.58	Alpha-1,3-mannosyltransferase

0.42	GO:0097502	mannosylation
0.41	GO:0006955	immune response
0.39	GO:0007275	multicellular organism development
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.36	GO:0036211	protein modification process
0.35	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.34	GO:0015031	protein transport
0.33	GO:0006508	proteolysis

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.43	GO:0005164	tumor necrosis factor receptor binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding

0.70	GO:0005783	endoplasmic reticulum
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0031984	organelle subcompartment
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016758

sp|Q27350|SO_DROME
Protein sine oculis
Search

SIX1

0.91	Sine oculis Homeobox like 1

0.63	GO:0008283	cell proliferation
0.63	GO:0048513	animal organ development
0.61	GO:0006915	apoptotic process
0.58	GO:0060788	ectodermal placode formation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0035270	endocrine system development
0.53	GO:0016477	cell migration
0.52	GO:0022008	neurogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0003700	DNA binding transcription factor activity
0.46	GO:0008134	transcription factor binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003682	chromatin binding
0.44	GO:0003690	double-stranded DNA binding
0.33	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.42	GO:0043233	organelle lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q27364|Q27364_DROME
Ecdysone-induced gene 71Eb, isoform A
Search

0.19	Ecdysone-induced gene 71Eb, isoform A

0.78

GO:0042742

defense response to bacterium

0.66

GO:0005576

extracellular region

sp|Q27367|CRQ_DROME
Protein croquemort
Search

0.79	Scavenger receptor class B

0.56	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
0.55	GO:0090382	phagosome maturation
0.51	GO:0006915	apoptotic process
0.37	GO:0060099	regulation of phagocytosis, engulfment
0.37	GO:0048102	autophagic cell death
0.37	GO:0006911	phagocytosis, engulfment
0.36	GO:0042116	macrophage activation
0.35	GO:0006955	immune response
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006457	protein folding

0.40	GO:0004872	receptor activity
0.34	GO:0051082	unfolded protein binding
0.33	GO:0048038	quinone binding
0.32	GO:0051287	NAD binding
0.32	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.42	GO:0005764	lysosome
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:1.6

GO:0016651

sp|Q27368|E2F1_DROME
Transcription factor E2f1
Search

E2F1

0.82	E2F transcription factor 1, isoform F

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0008284	positive regulation of cell proliferation
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0043065	positive regulation of apoptotic process
0.43	GO:0006915	apoptotic process
0.43	GO:0045477	regulation of nurse cell apoptotic process
0.43	GO:0007307	eggshell chorion gene amplification

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0008134	transcription factor binding
0.34	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0016740	transferase activity

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.35	GO:0005694	chromosome
0.34	GO:0015630	microtubule cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0016740

sp|Q27377|OB10_DROME
Putative odorant-binding protein A10
Search

0.62	Chemosensory protein 2

0.39

GO:0016310

phosphorylation

0.40

GO:0016301

kinase activity

0.49	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q27403|GCM_DROME
Transcription factor glial cells missing
Search

GCM

0.86	Transcription factor glial cells missing

0.70	GO:0007275	multicellular organism development
0.61	GO:0042690	negative regulation of crystal cell differentiation
0.60	GO:0042387	plasmatocyte differentiation
0.60	GO:0042688	crystal cell differentiation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060856	establishment of blood-brain barrier
0.53	GO:0050764	regulation of phagocytosis

0.55	GO:0003677	DNA binding
0.52	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0015035	protein disulfide oxidoreductase activity
0.33	GO:0003777	microtubule motor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.33	GO:0016459	myosin complex

tr|Q27411|Q27411_DROME
Rlb1
Search

0.12

triadin

0.46	GO:0030490	maturation of SSU-rRNA
0.37	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.36	GO:0006401	RNA catabolic process

0.37	GO:0000175	3'-5'-exoribonuclease activity
0.35	GO:0046872	metal ion binding
0.34	GO:0008484	sulfuric ester hydrolase activity
0.33	GO:0016779	nucleotidyltransferase activity
0.33	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.47	GO:0030686	90S preribosome
0.37	GO:0000178	exosome (RNase complex)
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37

EC:3.1.13

GO:0000175

sp|Q27415|NLP_DROME
Nucleoplasmin-like protein
Search

0.90	Nucleoplasmin

0.87	GO:0035041	sperm chromatin decondensation
0.78	GO:0006338	chromatin remodeling

0.80

GO:0042393

histone binding

0.80	GO:0005705	polytene chromosome interband
0.67	GO:0005730	nucleolus
0.49	GO:0005737	cytoplasm
0.41	GO:0005654	nucleoplasm

sp|Q27421|OSP_DROME
Protein outspread
Search

0.35

GO:0008270

zinc ion binding

0.37	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|Q27571|NOS_DROME
Nitric oxide synthase
Search

0.69	Nitric oxide salivary gland

0.83	GO:0006809	nitric oxide biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0008016	regulation of heart contraction
0.48	GO:0007399	nervous system development
0.44	GO:0007263	nitric oxide mediated signal transduction
0.42	GO:0031284	positive regulation of guanylate cyclase activity
0.40	GO:1901206	positive regulation of adrenergic receptor signaling pathway involved in heart process
0.40	GO:0098923	retrograde trans-synaptic signaling by soluble gas
0.40	GO:0099548	trans-synaptic signaling by nitric oxide
0.40	GO:0051612	negative regulation of serotonin uptake

0.84	GO:0004517	nitric-oxide synthase activity
0.76	GO:0005516	calmodulin binding
0.70	GO:0010181	FMN binding
0.68	GO:0050661	NADP binding
0.64	GO:0050660	flavin adenine dinucleotide binding
0.61	GO:0020037	heme binding
0.61	GO:0005506	iron ion binding
0.41	GO:0003958	NADPH-hemoprotein reductase activity

0.39	GO:0030315	T-tubule
0.39	GO:0033017	sarcoplasmic reticulum membrane
0.38	GO:0005901	caveola
0.38	GO:0030018	Z disc
0.37	GO:0045202	synapse
0.36	GO:0005654	nucleoplasm
0.36	GO:0005856	cytoskeleton
0.36	GO:0005777	peroxisome
0.35	GO:0005739	mitochondrion

0.84

EC:1.14.13.39

GO:0004517

sp|Q27575|PSA73_DROME
Proteasome subunit alpha type-7-1B
Search

0.51	Proteasome subunit alpha type

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0010498	proteasomal protein catabolic process
0.34	GO:0008063	Toll signaling pathway
0.34	GO:0007623	circadian rhythm

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.33	GO:0042802	identical protein binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.60	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.34	GO:0098794	postsynapse
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

sp|Q27580|SAHH_DROME
Adenosylhomocysteinase
Search

0.56	Adenosylhomocysteinase A

0.78	GO:0019510	S-adenosylhomocysteine catabolic process
0.72	GO:0006730	one-carbon metabolic process
0.46	GO:0033353	S-adenosylmethionine cycle
0.34	GO:0048033	heme o metabolic process
0.34	GO:0007163	establishment or maintenance of cell polarity
0.33	GO:0006783	heme biosynthetic process

0.80	GO:0004013	adenosylhomocysteinase activity
0.66	GO:0051287	NAD binding
0.34	GO:0030552	cAMP binding
0.34	GO:0008495	protoheme IX farnesyltransferase activity

0.44	GO:0005829	cytosol
0.36	GO:0042470	melanosome
0.35	GO:0031002	actin rod
0.34	GO:0031941	filamentous actin
0.34	GO:0045335	phagocytic vesicle
0.34	GO:0031252	cell leading edge
0.34	GO:0005938	cell cortex
0.33	GO:0005615	extracellular space
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80

EC:3.3.1.1

GO:0004013

sp|Q27589|CP4D2_DROME
Cytochrome P450 4d2
Search

0.40	Putative cytochrome

0.53

GO:0055114

oxidation-reduction process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q27591|ITBN_DROME
Integrin beta-nu
Search

0.59	Integrin beta-nu

0.79	GO:0007229	integrin-mediated signaling pathway
0.71	GO:0007155	cell adhesion
0.60	GO:0035011	melanotic encapsulation of foreign target
0.59	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.58	GO:0043277	apoptotic cell clearance
0.58	GO:0046716	muscle cell cellular homeostasis
0.39	GO:0030199	collagen fibril organization
0.37	GO:0007044	cell-substrate junction assembly
0.35	GO:0048870	cell motility
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.52	GO:0046982	protein heterodimerization activity
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0004872	receptor activity
0.34	GO:0008201	heparin binding
0.33	GO:0016740	transferase activity
0.33	GO:0032403	protein complex binding
0.32	GO:0003682	chromatin binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0005102	receptor binding
0.32	GO:0004222	metalloendopeptidase activity

0.56	GO:0008305	integrin complex
0.37	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0032777	Piccolo NuA4 histone acetyltransferase complex
0.33	GO:0005615	extracellular space
0.33	GO:0044420	extracellular matrix component
0.33	GO:0035003	subapical complex
0.33	GO:0009986	cell surface
0.32	GO:0031982	vesicle
0.32	GO:0099512	supramolecular fiber
0.32	GO:0005912	adherens junction

0.33

GO:0016740

sp|Q27593|CP6A8_DROME
Cytochrome P450 6a8
Search

0.10	Cytochrome P450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0017085	response to insecticide
0.49	GO:0031000	response to caffeine
0.45	GO:0048252	lauric acid metabolic process
0.40	GO:0006805	xenobiotic metabolic process
0.39	GO:0009404	toxin metabolic process
0.34	GO:0002118	aggressive behavior
0.34	GO:0050829	defense response to Gram-negative bacterium
0.34	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0009055	electron transfer activity

0.40	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q27594|CP6A9_DROME
Cytochrome P450 6a9
Search

0.37	Cytochrome P450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0017085	response to insecticide
0.47	GO:0031000	response to caffeine
0.41	GO:0048252	lauric acid metabolic process
0.38	GO:0006805	xenobiotic metabolic process
0.37	GO:0009404	toxin metabolic process
0.34	GO:0002118	aggressive behavior
0.34	GO:0050829	defense response to Gram-negative bacterium
0.34	GO:0006091	generation of precursor metabolites and energy

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0009055	electron transfer activity

0.39	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q27597|NCPR_DROME
NADPH--cytochrome P450 reductase
Search

0.68	NADPH--cytochrome P450 reductase

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006723	cuticle hydrocarbon biosynthetic process

0.81	GO:0003958	NADPH-hemoprotein reductase activity
0.70	GO:0010181	FMN binding
0.66	GO:0050661	NADP binding
0.62	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:1.6.2.4

GO:0003958

sp|Q27601|PUR1_DROME
Amidophosphoribosyltransferase
Search

0.52	Amidophosphoribosyltransferase

0.75	GO:0009113	purine nucleobase biosynthetic process
0.67	GO:0006189	'de novo' IMP biosynthetic process
0.66	GO:0009116	nucleoside metabolic process
0.47	GO:0040016	embryonic cleavage
0.45	GO:0008340	determination of adult lifespan
0.44	GO:0048477	oogenesis
0.35	GO:0006541	glutamine metabolic process

0.79	GO:0004044	amidophosphoribosyltransferase activity
0.62	GO:0051536	iron-sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.32	GO:0003723	RNA binding

0.30

GO:0031224

intrinsic component of membrane

0.79	EC:2.4.2.14	GO:0004044
0.79	KEGG:R01072	GO:0004044

sp|Q27606|CP4E2_DROME
Cytochrome P450 4e2
Search

0.42	Cytochrome P450 monooxygenase CYP4BR7

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0030258	lipid modification
0.32	GO:0006631	fatty acid metabolic process
0.32	GO:0006508	proteolysis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0008236	serine-type peptidase activity

0.42	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0031090	organelle membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q27607|DPOG1_DROME
DNA polymerase subunit gamma-1, mitochondrial
Search

0.82	Dna polymerase subunit gamma-mitochondrial

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.58	GO:0019896	axonal transport of mitochondrion
0.58	GO:0032042	mitochondrial DNA metabolic process
0.39	GO:0006287	base-excision repair, gap-filling
0.39	GO:0007562	eclosion
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.38	GO:0007568	aging
0.35	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation
0.35	GO:0032543	mitochondrial translation

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0003677	DNA binding
0.40	GO:0008408	3'-5' exonuclease activity
0.38	GO:0002020	protease binding
0.37	GO:0003682	chromatin binding
0.35	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

0.85	GO:0005760	gamma DNA polymerase complex
0.56	GO:1904115	axon cytoplasm
0.38	GO:0042645	mitochondrial nucleoid
0.36	GO:0043234	protein complex
0.34	GO:0043195	terminal bouton
0.34	GO:0048475	coated membrane
0.33	GO:0070062	extracellular exosome
0.32	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0003887

sp|Q27869|PIMT_DROME
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Search

0.31	L-isoaspartate(D-aspartate) O-methyltransferase

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.44	GO:0042742	defense response to bacterium
0.33	GO:0001522	pseudouridine synthesis

0.79	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
0.35	GO:0005509	calcium ion binding
0.33	GO:0009982	pseudouridine synthase activity
0.32	GO:0003723	RNA binding

0.34	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.1.1.77

GO:0004719

sp|Q27884|PPP6_DROME
Serine/threonine-protein phosphatase 6 catalytic subunit
Search

0.52	Serine/threonine-protein phosphatase 6 catalytic subunit

0.71	GO:0006470	protein dephosphorylation
0.46	GO:0046329	negative regulation of JNK cascade
0.45	GO:0000082	G1/S transition of mitotic cell cycle
0.40	GO:0001878	response to yeast
0.36	GO:0045087	innate immune response
0.34	GO:0048208	COPII vesicle coating

0.72	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005829	cytosol
0.34	GO:0000139	Golgi membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0004721

sp|Q27889|PP2B2_DROME
Serine/threonine-protein phosphatase 2B catalytic subunit 2
Search

0.51	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.47	GO:0030431	sleep
0.39	GO:0007143	female meiotic nuclear division
0.39	GO:0035220	wing disc development
0.39	GO:0045995	regulation of embryonic development

0.72	GO:0004721	phosphoprotein phosphatase activity
0.36	GO:0005516	calmodulin binding
0.33	GO:0046872	metal ion binding

0.36	GO:0005955	calcineurin complex
0.30	GO:0016020	membrane

0.72

GO:0004721

sp|Q27896|TRF_DROME
TBP-related factor
Search

0.54	TATA box binding protein like 2

0.69	GO:0006352	DNA-templated transcription, initiation
0.41	GO:0009880	embryonic pattern specification
0.41	GO:0009792	embryo development ending in birth or egg hatching
0.40	GO:0030097	hemopoiesis
0.38	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0006366	transcription by RNA polymerase II
0.35	GO:0007369	gastrulation
0.35	GO:0006359	regulation of transcription by RNA polymerase III
0.35	GO:0006383	transcription by RNA polymerase III
0.33	GO:0006413	translational initiation

0.55	GO:0003677	DNA binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0003743	translation initiation factor activity
0.30	GO:0001093	TFIIB-class transcription factor binding
0.30	GO:0001092	TFIIA-class transcription factor binding

0.42	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0005667	transcription factor complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0043228	non-membrane-bounded organelle

0.36

GO:0032440

sp|Q27934|PHYL_DROME
Protein phyllopod
Search

0.12

Phyl

0.85	GO:0007462	R1/R6 cell fate commitment
0.83	GO:0007465	R7 cell fate commitment
0.81	GO:0016360	sensory organ precursor cell fate determination
0.77	GO:0045746	negative regulation of Notch signaling pathway
0.75	GO:0007422	peripheral nervous system development
0.75	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.74	GO:0007265	Ras protein signal transduction
0.69	GO:0010498	proteasomal protein catabolic process
0.50	GO:0045467	R7 cell development
0.47	GO:0007219	Notch signaling pathway

0.77	GO:0043621	protein self-association
0.72	GO:0030674	protein binding, bridging
0.49	GO:0008270	zinc ion binding
0.34	GO:0003723	RNA binding

0.69	GO:0000151	ubiquitin ligase complex
0.61	GO:0005634	nucleus

tr|Q29QL9|Q29QL9_DROME
IP07080p
Search

PEBPH

0.89	Phosphatidylethanolamine-binding protein homolog F40A3.3

tr|Q29QN4|Q29QN4_DROME
CG7849
Search

0.59	probable tRNA pseudouridine synthase 2

0.72	GO:0001522	pseudouridine synthesis
0.63	GO:0006396	RNA processing

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding

0.38

GO:0005829

cytosol

0.72

EC:5.4.99.12

GO:0009982

tr|Q29QP4|Q29QP4_DROME
CG13178
Search

0.45

GO:0060271

cilium assembly

0.75

GO:0042803

protein homodimerization activity

0.72	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.61	GO:0005634	nucleus
0.61	GO:0005739	mitochondrion
0.56	GO:0005886	plasma membrane

tr|Q29QP5|Q29QP5_DROME
IP09539p
Search

0.30

GO:0044425

membrane part

tr|Q29QQ9|Q29QQ9_DROME
IP10364p
Search

EXOSC7

0.66	Exosome component 7

0.58	GO:0034473	U1 snRNA 3'-end processing
0.58	GO:0071047	polyadenylation-dependent mRNA catabolic process
0.58	GO:0034476	U5 snRNA 3'-end processing
0.57	GO:0034475	U4 snRNA 3'-end processing
0.57	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.57	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process
0.57	GO:0000467	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.57	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process
0.57	GO:0071028	nuclear mRNA surveillance
0.56	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'

0.57	GO:0017091	AU-rich element binding
0.51	GO:0004527	exonuclease activity
0.37	GO:0004540	ribonuclease activity

0.72	GO:0000178	exosome (RNase complex)
0.65	GO:0005652	nuclear lamina
0.44	GO:0005737	cytoplasm
0.36	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|Q29QS8|Q29QS8_DROME
IP11711p
Search

0.38

GO:0003677

DNA binding

0.41

GO:0005634

nucleus

tr|Q29QT4|Q29QT4_DROME
IP12060p
Search

0.13	Cysteine--tRNA ligase

0.40

GO:0016874

ligase activity

0.30

GO:0044425

membrane part

0.40

GO:0016874

tr|Q29QW0|Q29QW0_DROME
IP14311p
Search

0.57	GO:0006413	translational initiation
0.43	GO:0032793	positive regulation of CREB transcription factor activity
0.43	GO:0051289	protein homotetramerization
0.42	GO:0061098	positive regulation of protein tyrosine kinase activity
0.40	GO:0007166	cell surface receptor signaling pathway
0.39	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.39	GO:1903474	anchoring of the mitotic actomyosin contractile ring to the plasma membrane
0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0007500	mesodermal cell fate determination

0.58	GO:0003743	translation initiation factor activity
0.44	GO:0008140	cAMP response element binding protein binding
0.42	GO:0030296	protein tyrosine kinase activator activity
0.39	GO:0004930	G-protein coupled receptor activity
0.39	GO:0003712	transcription cofactor activity
0.38	GO:0046983	protein dimerization activity
0.38	GO:0003677	DNA binding
0.37	GO:0003682	chromatin binding
0.37	GO:0042802	identical protein binding
0.36	GO:0042393	histone binding

0.43	GO:0005634	nucleus
0.41	GO:0005912	adherens junction
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0005700	polytene chromosome
0.37	GO:0044446	intracellular organelle part
0.37	GO:1990234	transferase complex
0.35	GO:1905368	peptidase complex
0.35	GO:0043234	protein complex
0.35	GO:0005737	cytoplasm
0.34	GO:1904949	ATPase complex

0.36

GO:0008168

tr|Q29R09|Q29R09_DROME
CG2924, isoform A
Search

0.49	Ubiquitin-conjugating enzyme

0.67	GO:0070936	protein K48-linked ubiquitination
0.63	GO:0070459	prolactin secretion
0.59	GO:0007617	mating behavior
0.58	GO:0009566	fertilization
0.56	GO:0061458	reproductive system development
0.53	GO:0001967	suckling behavior
0.52	GO:0007566	embryo implantation

0.66	GO:0004842	ubiquitin-protein transferase activity
0.60	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.45	GO:0016874	ligase activity

0.30

GO:0031224

intrinsic component of membrane

0.45	EC:6	GO:0016874
0.66	KEGG:R03876	GO:0004842

tr|Q29R10|Q29R10_DROME
CG7987, isoform A
Search

0.47	Zinc finger protein Xfin

0.38

GO:0000122

negative regulation of transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.39	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding

0.35

GO:0005634

nucleus

tr|Q29R14|Q29R14_DROME
LP01683p
Search

LOC108099768

0.67	Transcriptional repressor scratch 2

0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:2001222	regulation of neuron migration
0.38	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator
0.38	GO:2000177	regulation of neural precursor cell proliferation
0.37	GO:0043523	regulation of neuron apoptotic process
0.36	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.34	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.33	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.40	GO:0001133	RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding
0.35	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0046872	metal ion binding

0.37	GO:0005634	nucleus
0.34	GO:0000785	chromatin
0.34	GO:0031974	membrane-enclosed lumen

tr|Q29R15|Q29R15_DROME
LP17019p
Search

LOC108087535

0.80	mediator of RNA polymerase II transcription subunit 15 isoform X2

0.45	GO:0070887	cellular response to chemical stimulus
0.45	GO:0006979	response to oxidative stress
0.44	GO:0098754	detoxification
0.40	GO:0031323	regulation of cellular metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0080090	regulation of primary metabolic process
0.39	GO:0009889	regulation of biosynthetic process
0.39	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.39	GO:0005987	sucrose catabolic process

0.48	GO:0004602	glutathione peroxidase activity
0.39	GO:0003677	DNA binding
0.38	GO:0003700	DNA binding transcription factor activity
0.38	GO:0015616	DNA translocase activity
0.38	GO:0001102	RNA polymerase II activating transcription factor binding
0.38	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.36	GO:0003730	mRNA 3'-UTR binding
0.36	GO:0046872	metal ion binding
0.35	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.35	GO:0031625	ubiquitin protein ligase binding

0.40	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:1902494	catalytic complex
0.36	GO:0000785	chromatin
0.36	GO:0035324	female germline ring canal
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.48

EC:1.11.1.9

GO:0004602

tr|Q2MGK0|Q2MGK0_DROME
Chemosensory protein A 84a
Search

0.18	Chemosensory protein A 84a

0.75

GO:0007606

sensory perception of chemical stimulus

0.66

GO:0005576

extracellular region

tr|Q2MGK1|Q2MGK1_DROME
Uncharacterized protein, isoform C
Search

0.37

GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

0.30

GO:0044425

membrane part

0.37

GO:0016747

tr|Q2MGK5|Q2MGK5_DROME
CG4970
Search

tr|Q2MGK7|Q2MGK7_DROME
GEO13330p1
Search

0.11	Ankyrin repeat domain-containing protein

0.69	GO:0009890	negative regulation of biosynthetic process
0.39	GO:0000165	MAPK cascade

0.39	GO:0004707	MAP kinase activity
0.37	GO:0005509	calcium ion binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008144	drug binding

0.33	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.39	EC:2.7.11.24	GO:0004707
0.39	KEGG:R00162	GO:0004707

sp|Q2MGL3|POP7_DROME
Ribonuclease P protein subunit p20
Search

POP7

0.92	Ribonuclease P protein subunit like protein (Fragment)

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.66	GO:0008033	tRNA processing
0.38	GO:0006364	rRNA processing

0.79	GO:0004526	ribonuclease P activity
0.51	GO:0003676	nucleic acid binding
0.42	GO:0000171	ribonuclease MRP activity
0.37	GO:0005515	protein binding

0.62	GO:0005730	nucleolus
0.61	GO:0030681	multimeric ribonuclease P complex
0.60	GO:0000172	ribonuclease MRP complex
0.46	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

0.79

EC:3.1.26.5

GO:0004526

tr|Q2MGL5|Q2MGL5_DROME
Uncharacterized protein
Search

0.39	GO:0007017	microtubule-based process
0.39	GO:0007010	cytoskeleton organization

0.41	GO:0005200	structural constituent of cytoskeleton
0.38	GO:0003924	GTPase activity
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.35	GO:0032553	ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

tr|Q2MGL7|Q2MGL7_DROME
Uncharacterized protein, isoform A
Search

tr|Q2MGL8|Q2MGL8_DROME
Uncharacterized protein
Search

0.49	alpha-tocopherol transfer protein isoform X1

0.67	GO:0030036	actin cytoskeleton organization
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.44	GO:0044719	regulation of imaginal disc-derived wing size
0.44	GO:0008039	synaptic target recognition
0.44	GO:0016203	muscle attachment

0.71	GO:0017048	Rho GTPase binding
0.69	GO:0003779	actin binding
0.44	GO:0004930	G-protein coupled receptor activity
0.39	GO:0005509	calcium ion binding

0.44	GO:0005927	muscle tendon junction
0.30	GO:0016020	membrane

tr|Q2MGL9|Q2MGL9_DROME
RT07682p
Search

0.56	Phosphatidylinositol transfer protein SEC14

0.74

GO:0030036

actin cytoskeleton organization

0.77	GO:0017048	Rho GTPase binding
0.74	GO:0003779	actin binding

tr|Q2MGM0|Q2MGM0_DROME
Ionotropic receptor 62a
Search

0.17	Ionotropic receptor 62a

0.48	GO:0009593	detection of chemical stimulus
0.40	GO:0055085	transmembrane transport

0.48	GO:0022834	ligand-gated channel activity
0.47	GO:0022839	ion gated channel activity
0.46	GO:0008381	mechanosensitive ion channel activity
0.42	GO:0015318	inorganic molecular entity transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|Q2MGN0|Q2MGN0_DROME
CG3065, isoform A
Search

0.52	zinc finger protein Xfin

0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.39	GO:1902070	positive regulation of sphingolipid mediated signaling pathway
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0007010	cytoskeleton organization
0.34	GO:0022604	regulation of cell morphogenesis
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.44	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.37	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.33	GO:0008201	heparin binding

0.42	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.37	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0031090	organelle membrane
0.32	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

tr|Q2MGP2|Q2MGP2_DROME
Uncharacterized protein
Search

tr|Q2MGP3|Q2MGP3_DROME
Uncharacterized protein
Search

tr|Q2MGP4|Q2MGP4_DROME
Uncharacterized protein
Search

tr|Q2MGP5|Q2MGP5_DROME
Uncharacterized protein
Search

tr|Q2MGP6|Q2MGP6_DROME
Uncharacterized protein
Search

tr|Q2MGP7|Q2MGP7_DROME
Uncharacterized protein
Search

tr|Q2PDM3|Q2PDM3_DROME
Uncharacterized protein, isoform C
Search

0.34	GO:0016310	phosphorylation
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.68	GO:0005509	calcium ion binding
0.34	GO:0016301	kinase activity
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0003676	nucleic acid binding

0.48	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004523

tr|Q2PDP5|Q2PDP5_DROME
Uncharacterized protein, isoform F
Search

0.84	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.39	GO:0032504	multicellular organism reproduction

0.85	GO:0004656	procollagen-proline 4-dioxygenase activity
0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.48	GO:0031418	L-ascorbic acid binding
0.42	GO:0005506	iron ion binding

0.70	GO:0005783	endoplasmic reticulum
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.85	EC:1.14.11.2	GO:0004656
0.85	KEGG:R03219	GO:0004656

tr|Q2PDP6|Q2PDP6_DROME
FI18136p1
Search

0.58	RNA exonuclease 1

0.51	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:0006265	DNA topological change
0.34	GO:0006744	ubiquinone biosynthetic process
0.33	GO:0006414	translational elongation
0.33	GO:0032259	methylation
0.32	GO:0006468	protein phosphorylation
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0007155	cell adhesion
0.32	GO:0002168	instar larval development

0.54	GO:0004527	exonuclease activity
0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.35	GO:0003917	DNA topoisomerase type I activity
0.34	GO:0004395	hexaprenyldihydroxybenzoate methyltransferase activity
0.34	GO:0008689	3-demethylubiquinone-9 3-O-methyltransferase activity
0.34	GO:0008425	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
0.33	GO:0061505	DNA topoisomerase II activity
0.33	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0004540	ribonuclease activity

0.41	GO:0016604	nuclear body
0.34	GO:0005694	chromosome
0.34	GO:0031314	extrinsic component of mitochondrial inner membrane
0.32	GO:0005665	DNA-directed RNA polymerase II, core complex
0.32	GO:0005618	cell wall
0.32	GO:0005730	nucleolus
0.32	GO:0005829	cytosol
0.32	GO:0005576	extracellular region
0.31	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:5.99.1.2

GO:0003917

tr|Q2PDQ0|Q2PDQ0_DROME
Uncharacterized protein
Search

0.44	GO:0045746	negative regulation of Notch signaling pathway
0.42	GO:0006493	protein O-linked glycosylation
0.42	GO:0006508	proteolysis

0.46	GO:0004222	metalloendopeptidase activity
0.44	GO:0042285	xylosyltransferase activity
0.33	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

0.46

GO:0004222

tr|Q2PDQ6|Q2PDQ6_DROME
Uncharacterized protein
Search

tr|Q2PDQ7|Q2PDQ7_DROME
GEO02541p1
Search

0.13	salivary glue protein Sgs-5

0.77

GO:0032504

multicellular organism reproduction

0.48

GO:0005615

extracellular space

tr|Q2PDR0|Q2PDR0_DROME
GEO11137p1
Search

0.59	Dolichol-phosphate mannosyltransferase subunit

0.74	GO:0006486	protein glycosylation
0.41	GO:0006506	GPI anchor biosynthetic process
0.41	GO:0097502	mannosylation
0.33	GO:0055085	transmembrane transport

0.48	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0033185	dolichol-phosphate-mannose synthase complex
0.39	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.48

GO:0016757

tr|Q2PDS0|Q2PDS0_DROME
Uncharacterized protein, isoform A
Search

tr|Q2PDT4|Q2PDT4_DROME
Paxillin, isoform F
Search

0.77	Focal contact protein paxillin

0.82	GO:0007160	cell-matrix adhesion
0.57	GO:0046843	dorsal appendage formation
0.57	GO:1901739	regulation of myoblast fusion
0.57	GO:0035218	leg disc development
0.55	GO:0035220	wing disc development
0.51	GO:0043087	regulation of GTPase activity
0.50	GO:0010506	regulation of autophagy
0.47	GO:0007016	cytoskeletal anchoring at plasma membrane

0.54	GO:0046872	metal ion binding
0.31	GO:0016740	transferase activity

0.69	GO:0005856	cytoskeleton
0.58	GO:0005927	muscle tendon junction
0.54	GO:0005925	focal adhesion
0.42	GO:0005829	cytosol

0.31

GO:0016740

tr|Q2PDU0|Q2PDU0_DROME
GEO11169p1
Search

0.53	nephronectin

0.63

GO:0042742

defense response to bacterium

0.55	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|Q2PDV0|Q2PDV0_DROME
Uncharacterized protein
Search

0.68

GO:0008080

N-acetyltransferase activity

0.68

GO:0008080

tr|Q2PDV5|Q2PDV5_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|Q2PDW6|Q2PDW6_DROME
Cp110, isoform B
Search

0.85	GO:0007099	centriole replication
0.79	GO:0032465	regulation of cytokinesis
0.70	GO:1903723	negative regulation of centriole elongation

0.83

GO:0005814

centriole

tr|Q2PDX2|Q2PDX2_DROME
Uncharacterized protein, isoform B
Search

0.79	GO:0007064	mitotic sister chromatid cohesion
0.54	GO:0006367	transcription initiation from RNA polymerase II promoter
0.51	GO:0006289	nucleotide-excision repair
0.49	GO:0032392	DNA geometric change
0.43	GO:0009226	nucleotide-sugar biosynthetic process
0.37	GO:0055114	oxidation-reduction process
0.35	GO:0042147	retrograde transport, endosome to Golgi
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.50	GO:0004003	ATP-dependent DNA helicase activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0003677	DNA binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0050662	coenzyme binding
0.37	GO:0016491	oxidoreductase activity
0.35	GO:0035091	phosphatidylinositol binding
0.34	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity

0.81	GO:0031390	Ctf18 RFC-like complex
0.34	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.37

GO:0016491

tr|Q2PDY3|Q2PDY3_DROME
CG7255, isoform F
Search

0.52	High affinity cationic amino acid transporter 1

0.55	GO:0055085	transmembrane transport
0.44	GO:0006865	amino acid transport
0.42	GO:0055088	lipid homeostasis
0.41	GO:0040007	growth
0.34	GO:0050829	defense response to Gram-negative bacterium
0.33	GO:0045824	negative regulation of innate immune response

0.57	GO:0022857	transmembrane transporter activity
0.32	GO:0016787	hydrolase activity

0.33

GO:0005887

integral component of plasma membrane

0.32

GO:0016787

tr|Q2PDY6|Q2PDY6_DROME
MIP32234p1
Search

0.77

GO:0006030

chitin metabolic process

0.76	GO:0008061	chitin binding
0.33	GO:0003677	DNA binding
0.30	GO:0003824	catalytic activity

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q2PDY7|Q2PDY7_DROME
Uncharacterized protein
Search

0.10	Peritrophin-1

0.78

GO:0006030

chitin metabolic process

0.77

GO:0008061

chitin binding

0.66

GO:0005576

extracellular region

tr|Q2PDY8|Q2PDY8_DROME
Uncharacterized protein
Search

0.11	probable chitinase 3

0.78

GO:0006030

chitin metabolic process

0.77

GO:0008061

chitin binding

0.66

GO:0005576

extracellular region

tr|Q2PDZ1|Q2PDZ1_DROME
Uncharacterized protein, isoform B
Search

0.78

GO:0006030

chitin metabolic process

0.77

GO:0008061

chitin binding

0.66

GO:0005576

extracellular region

tr|Q2PDZ4|Q2PDZ4_DROME
Uncharacterized protein
Search

0.11	venom allergen 5

0.66	GO:0032504	multicellular organism reproduction
0.41	GO:0098656	anion transmembrane transport
0.41	GO:0015698	inorganic anion transport
0.35	GO:0007229	integrin-mediated signaling pathway
0.35	GO:0007155	cell adhesion

0.44	GO:0005452	inorganic anion exchanger activity
0.35	GO:0008658	penicillin binding
0.34	GO:0003723	RNA binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016829	lyase activity
0.33	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding

0.46	GO:0005615	extracellular space
0.35	GO:0008305	integrin complex
0.34	GO:0005634	nucleus

0.33

EC:4

GO:0016829

tr|Q2PE06|Q2PE06_DROME
Uncharacterized protein
Search

0.84	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination

0.74

GO:0004842

ubiquitin-protein transferase activity

0.83

GO:0019005

SCF ubiquitin ligase complex

0.74

GO:0004842

tr|Q2PE08|Q2PE08_DROME
Uncharacterized protein, isoform A
Search

0.66	Glycoprotein-N-acetylgalactosamine

0.77	GO:0016266	O-glycan processing
0.43	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.43	GO:0021551	central nervous system morphogenesis
0.42	GO:0051489	regulation of filopodium assembly
0.42	GO:0007528	neuromuscular junction development
0.41	GO:0055001	muscle cell development
0.39	GO:0009247	glycolipid biosynthetic process
0.38	GO:0032504	multicellular organism reproduction
0.32	GO:0005975	carbohydrate metabolic process

0.81	GO:0048531	beta-1,3-galactosyltransferase activity
0.74	GO:0140103	catalytic activity, acting on a glycoprotein
0.37	GO:0046872	metal ion binding
0.34	GO:0008146	sulfotransferase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.30

GO:0016020

membrane

0.34

EC:2.8.2

GO:0008146

tr|Q2PE11|Q2PE11_DROME
Uncharacterized protein, isoform B
Search

0.10	Carcinoembryonic antigen-related cell adhesion molecule 1

0.46	GO:0032259	methylation
0.45	GO:0043043	peptide biosynthetic process
0.42	GO:0044267	cellular protein metabolic process
0.42	GO:0010467	gene expression
0.41	GO:0009059	macromolecule biosynthetic process

0.46	GO:0008168	methyltransferase activity
0.34	GO:0016874	ligase activity

0.30

GO:0031224

intrinsic component of membrane

0.46

GO:0008168

tr|Q2PE13|Q2PE13_DROME
Activating transcription factor-2
Search

0.53	cyclic AMP-dependent transcription factor ATF-2

0.73	GO:0070829	heterochromatin maintenance
0.73	GO:0031453	positive regulation of heterochromatin assembly
0.72	GO:0010866	regulation of triglyceride biosynthetic process
0.72	GO:0002385	mucosal immune response
0.71	GO:0030431	sleep
0.69	GO:0051403	stress-activated MAPK cascade
0.67	GO:0009651	response to salt stress
0.66	GO:0071470	cellular response to osmotic stress
0.66	GO:0034605	cellular response to heat
0.62	GO:0006366	transcription by RNA polymerase II

0.67	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.62	GO:0042803	protein homodimerization activity
0.55	GO:0043565	sequence-specific DNA binding
0.34	GO:0003747	translation release factor activity
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0005198	structural molecule activity

0.73	GO:0005704	polytene chromosome band
0.73	GO:0005701	polytene chromosome chromocenter
0.70	GO:0031618	nuclear pericentric heterochromatin
0.35	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.35	GO:0030132	clathrin coat of coated pit
0.30	GO:0016021	integral component of membrane

0.34

EC:1.2.1

GO:0016620

sp|Q2PE14|ZCHC8_DROME
Zinc finger CCHC domain-containing protein 8 homolog
Search

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0005515	protein binding

0.44

GO:0005654

nucleoplasm

tr|Q2PE16|Q2PE16_DROME
FI16615p1
Search

0.62	lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog

0.43	GO:0006915	apoptotic process
0.39	GO:0007165	signal transduction

0.40

GO:0004871

signal transducer activity

0.42	GO:0005794	Golgi apparatus
0.41	GO:0005654	nucleoplasm
0.30	GO:0044425	membrane part

tr|Q2PE19|Q2PE19_DROME
Uncharacterized protein
Search

0.10	threonine-rich protein

0.49	GO:0006508	proteolysis
0.46	GO:0006030	chitin metabolic process
0.39	GO:0006898	receptor-mediated endocytosis
0.36	GO:0007605	sensory perception of sound
0.34	GO:0007155	cell adhesion
0.33	GO:0005975	carbohydrate metabolic process

0.53	GO:0004252	serine-type endopeptidase activity
0.45	GO:0008061	chitin binding
0.41	GO:0005044	scavenger receptor activity
0.38	GO:0070001	aspartic-type peptidase activity
0.35	GO:0030248	cellulose binding
0.34	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding

0.44	GO:0005576	extracellular region
0.38	GO:0045095	keratin filament
0.34	GO:0005618	cell wall
0.30	GO:0016020	membrane

0.53

GO:0004252

tr|Q2PE22|Q2PE22_DROME
GEO11136p1
Search

0.30

GO:0044425

membrane part

tr|Q32KC6|Q32KC6_DROME
GH08757p
Search

0.49	GO:0007638	mechanosensory behavior
0.45	GO:0042391	regulation of membrane potential

0.30

GO:0031224

intrinsic component of membrane

sp|Q32KD2|SETB1_DROME
Histone-lysine N-methyltransferase eggless
Search

0.85	Histone-lysine N-methyltransferase eggless

0.78	GO:0034968	histone lysine methylation
0.69	GO:0044026	DNA hypermethylation
0.69	GO:0090309	positive regulation of methylation-dependent chromatin silencing
0.68	GO:0051038	negative regulation of transcription involved in meiotic cell cycle
0.68	GO:0048132	female germ-line stem cell asymmetric division
0.66	GO:0061647	histone H3-K9 modification
0.61	GO:0045814	negative regulation of gene expression, epigenetic
0.42	GO:0007275	multicellular organism development
0.39	GO:0006351	transcription, DNA-templated
0.35	GO:0045454	cell redox homeostasis

0.78	GO:0018024	histone-lysine N-methyltransferase activity
0.67	GO:0010385	double-stranded methylated DNA binding
0.62	GO:0008270	zinc ion binding
0.38	GO:0005515	protein binding
0.34	GO:1990841	promoter-specific chromatin binding
0.33	GO:0008233	peptidase activity

0.67	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.47	GO:0044446	intracellular organelle part
0.42	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0018024

tr|Q32KD4|Q32KD4_DROME
Argonaute-1, isoform A
Search

0.73	Eukaryotic translation initiation factor 2c

0.79	GO:0031047	gene silencing by RNA
0.46	GO:0090328	regulation of olfactory learning
0.46	GO:0098795	mRNA cleavage involved in gene silencing
0.46	GO:0046959	habituation
0.46	GO:0030727	germarium-derived female germ-line cyst formation
0.46	GO:0007294	germarium-derived oocyte fate determination
0.45	GO:0036099	female germ-line stem cell population maintenance
0.45	GO:0007367	segment polarity determination
0.44	GO:0016441	posttranscriptional gene silencing
0.44	GO:0031050	dsRNA fragmentation

0.51	GO:0003676	nucleic acid binding
0.41	GO:0019899	enzyme binding

0.43	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005634	nucleus
0.38	GO:0030529	intracellular ribonucleoprotein complex

tr|Q3HKQ0|Q3HKQ0_DROME
BG642163, isoform A
Search

0.59	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.55	GO:0007528	neuromuscular junction development
0.44	GO:0044718	siderophore transmembrane transport
0.43	GO:0072577	endothelial cell apoptotic process
0.43	GO:0030198	extracellular matrix organization
0.42	GO:0032835	glomerulus development
0.42	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0016525	negative regulation of angiogenesis
0.41	GO:0015031	protein transport
0.40	GO:0008283	cell proliferation

0.72	GO:0005201	extracellular matrix structural constituent
0.44	GO:0031992	energy transducer activity
0.44	GO:0015343	siderophore transmembrane transporter activity
0.41	GO:0005178	integrin binding
0.38	GO:0003682	chromatin binding
0.38	GO:0008061	chitin binding
0.36	GO:0004521	endoribonuclease activity
0.36	GO:0008134	transcription factor binding
0.36	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding

0.73	GO:0005604	basement membrane
0.70	GO:0005581	collagen trimer
0.61	GO:0098645	collagen network
0.55	GO:0031594	neuromuscular junction
0.41	GO:0030288	outer membrane-bounded periplasmic space
0.41	GO:0012505	endomembrane system
0.38	GO:0001725	stress fiber
0.37	GO:0005925	focal adhesion
0.37	GO:0043227	membrane-bounded organelle
0.37	GO:0005886	plasma membrane

tr|Q3HKQ1|Q3HKQ1_DROME
BG642167
Search

0.77

GO:0032504

multicellular organism reproduction

0.73

GO:0005615

extracellular space

tr|Q3HKQ3|Q3HKQ3_DROME
Male accessory gland protein
Search

0.86	Male accessory gland protein

0.47

GO:0032504

multicellular organism reproduction

0.48

GO:0004867

serine-type endopeptidase inhibitor activity

0.73

GO:0005615

extracellular space

sp|Q3LHL9|WGE_DROME
Protein winged eye
Search

0.72	GO:0030154	cell differentiation
0.43	GO:0031507	heterochromatin assembly
0.41	GO:0006342	chromatin silencing
0.41	GO:0007560	imaginal disc morphogenesis
0.32	GO:0006886	intracellular protein transport

0.77	GO:0003682	chromatin binding
0.40	GO:0000976	transcription regulatory region sequence-specific DNA binding

0.43	GO:0005677	chromatin silencing complex
0.39	GO:0000785	chromatin

tr|Q3YMU0|Q3YMU0_DROME
Protein disulfide-isomerase (Fragment)
Search

0.48	Disulfide-isomerase A3

0.69	GO:0045454	cell redox homeostasis
0.37	GO:0034976	response to endoplasmic reticulum stress
0.36	GO:0006457	protein folding

0.78	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds
0.55	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.67

GO:0005783

endoplasmic reticulum

0.78

EC:5.3.4

GO:0016864

tr|Q3ZAK6|Q3ZAK6_DROME
Chemosensory protein B 42a
Search

0.87	GO:0043695	detection of pheromone
0.83	GO:0008049	male courtship behavior
0.72	GO:0007606	sensory perception of chemical stimulus
0.63	GO:0065009	regulation of molecular function

0.80	GO:0044325	ion channel binding
0.77	GO:0016247	channel regulator activity
0.51	GO:0008289	lipid binding

0.70	GO:0005615	extracellular space
0.57	GO:0043234	protein complex

tr|Q3ZAL3|Q3ZAL3_DROME
IP12925p
Search

tr|Q3ZAL6|Q3ZAL6_DROME
IP13257p
Search

0.55

Spondin-1

0.75

GO:0010951

negative regulation of endopeptidase activity

0.78	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0004064	arylesterase activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1.1.2

GO:0004064

tr|Q3ZAN1|Q3ZAN1_DROME
Golgi pH regulator
Search

0.53	G protein coupled receptor

0.49	GO:0051452	intracellular pH reduction
0.46	GO:0007030	Golgi organization
0.43	GO:0098656	anion transmembrane transport
0.42	GO:0032940	secretion by cell
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0034765	regulation of ion transmembrane transport
0.34	GO:0043588	skin development
0.34	GO:0015031	protein transport

0.46	GO:0008308	voltage-gated anion channel activity
0.38	GO:0043565	sequence-specific DNA binding

0.43	GO:0012505	endomembrane system
0.41	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0044444	cytoplasmic part
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.33	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q3ZAP0|Q3ZAP0_DROME
GEO09975p1
Search

0.10

formin-2

0.46	GO:0007015	actin filament organization
0.43	GO:0007049	cell cycle
0.43	GO:0035023	regulation of Rho protein signal transduction
0.41	GO:0007160	cell-matrix adhesion
0.40	GO:0043044	ATP-dependent chromatin remodeling
0.40	GO:0065009	regulation of molecular function
0.39	GO:0045087	innate immune response
0.39	GO:0009405	pathogenesis
0.38	GO:0006265	DNA topological change
0.36	GO:0006468	protein phosphorylation

0.52	GO:0005509	calcium ion binding
0.52	GO:0003779	actin binding
0.51	GO:0017048	Rho GTPase binding
0.43	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.41	GO:0030246	carbohydrate binding
0.40	GO:0042393	histone binding
0.39	GO:0003723	RNA binding
0.39	GO:0003917	DNA topoisomerase type I activity
0.37	GO:0005524	ATP binding
0.37	GO:0004672	protein kinase activity

0.41	GO:0016514	SWI/SNF complex
0.38	GO:0005856	cytoskeleton
0.38	GO:0044462	external encapsulating structure part
0.38	GO:0019867	outer membrane
0.38	GO:0030313	cell envelope
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.39

EC:5.99.1.2

GO:0003917

tr|Q400N2|Q400N2_DROME
Pericentrin-like protein, isoform F
Search

PLP

0.97	A-kinase anchor protein 9 isoform X5

0.85	GO:0060285	cilium-dependent cell motility
0.80	GO:0007098	centrosome cycle
0.79	GO:0007605	sensory perception of sound
0.79	GO:0007020	microtubule nucleation
0.76	GO:0048598	embryonic morphogenesis
0.37	GO:0016310	phosphorylation
0.36	GO:0007165	signal transduction
0.34	GO:0032465	regulation of cytokinesis
0.34	GO:0006914	autophagy
0.33	GO:0006897	endocytosis

0.54	GO:0005515	protein binding
0.38	GO:0016301	kinase activity
0.36	GO:0005198	structural molecule activity
0.32	GO:0005549	odorant binding
0.32	GO:0003677	DNA binding
0.32	GO:0004984	olfactory receptor activity

0.80	GO:0005814	centriole
0.30	GO:0031224	intrinsic component of membrane

sp|Q45VV3|YAP1_DROME
Transcriptional coactivator yorkie
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0.95	Transcriptional coactivator yorkie

0.71	GO:0035329	hippo signaling
0.69	GO:0003007	heart morphogenesis
0.68	GO:0045927	positive regulation of growth
0.66	GO:0030855	epithelial cell differentiation
0.66	GO:0043066	negative regulation of apoptotic process
0.66	GO:0002009	morphogenesis of an epithelium
0.66	GO:0008284	positive regulation of cell proliferation
0.65	GO:0051094	positive regulation of developmental process
0.64	GO:0051240	positive regulation of multicellular organismal process
0.64	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation

0.66	GO:0003713	transcription coactivator activity
0.62	GO:0070064	proline-rich region binding
0.59	GO:0008022	protein C-terminus binding
0.58	GO:0008134	transcription factor binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.56	GO:0003682	chromatin binding
0.52	GO:0003714	transcription corepressor activity
0.49	GO:0046982	protein heterodimerization activity
0.41	GO:0016874	ligase activity

0.58	GO:0005829	cytosol
0.58	GO:0071148	TEAD-1-YAP complex
0.57	GO:0071149	TEAD-2-YAP complex
0.55	GO:0005770	late endosome
0.54	GO:0005764	lysosome
0.51	GO:0005654	nucleoplasm
0.36	GO:0000785	chromatin
0.30	GO:0016020	membrane

0.41	EC:6	GO:0016874
0.39	KEGG:R03876	GO:0004842

tr|Q45WI1|Q45WI1_DROME
ACP54A1
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tr|Q494G1|Q494G1_DROME
CG9864, isoform A
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0.38	Sodium-dependent phosphate transporter

0.55	GO:0055085	transmembrane transport
0.37	GO:0006820	anion transport
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.35	GO:0022857	transmembrane transporter activity
0.35	GO:0042302	structural constituent of cuticle
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.35	GO:0005886	plasma membrane
0.33	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|Q494G7|Q494G7_DROME
Major facilitator superfamily transporter 17, isoform F
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0.46	Sodium-dependent phosphate transporter

0.54	GO:0055085	transmembrane transport
0.36	GO:0006820	anion transport

0.38

GO:0005215

transporter activity

0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q494G8|Q494G8_DROME
F-box and leucine-rich repeat protein 6, isoform A
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0.43	F-box and leucine-rich repeat protein 6, isoform A

0.83	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.74	GO:0031647	regulation of protein stability
0.53	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.48	GO:0016567	protein ubiquitination
0.46	GO:0006030	chitin metabolic process

0.85	GO:0032093	SAM domain binding
0.48	GO:0004842	ubiquitin-protein transferase activity
0.46	GO:0008061	chitin binding

0.52	GO:0019005	SCF ubiquitin ligase complex
0.47	GO:0005654	nucleoplasm
0.43	GO:0005576	extracellular region
0.36	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.48

GO:0004842

tr|Q494K2|Q494K2_DROME
Ctf4
Search

WDHD1

0.56	WD repeat and HMG-box DNA-binding protein 1

0.85	GO:0035185	preblastoderm mitotic cell cycle
0.79	GO:0042023	DNA endoreduplication
0.35	GO:0009063	cellular amino acid catabolic process
0.34	GO:0055085	transmembrane transport
0.33	GO:0016485	protein processing
0.32	GO:0055114	oxidation-reduction process

0.43	GO:0003677	DNA binding
0.35	GO:0022857	transmembrane transporter activity
0.34	GO:0008942	nitrite reductase [NAD(P)H] activity

0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34	EC:1.7.1.4	GO:0008942
0.34	KEGG:R00787 KEGG:R00789	GO:0008942

tr|Q4AB20|Q4AB20_DROME
Uncharacterized protein
Search

0.39	GO:0007017	microtubule-based process
0.39	GO:0007010	cytoskeleton organization

0.40	GO:0005200	structural constituent of cytoskeleton
0.38	GO:0003924	GTPase activity
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.37	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.35	GO:0032553	ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016747

tr|Q4AB21|Q4AB21_DROME
FI12029p
Search

0.41	GO:0007017	microtubule-based process
0.41	GO:0007010	cytoskeleton organization

0.42	GO:0005200	structural constituent of cytoskeleton
0.40	GO:0003924	GTPase activity
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.36	GO:0032553	ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

tr|Q4AB23|Q4AB23_DROME
Uncharacterized protein
Search

0.35	GO:0006260	DNA replication
0.35	GO:0006281	DNA repair
0.34	GO:0097659	nucleic acid-templated transcription
0.34	GO:0006355	regulation of transcription, DNA-templated
0.33	GO:0010467	gene expression

0.37	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.33	GO:0003677	DNA binding

0.35	GO:0005694	chromosome
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.37